WorldWideScience

Sample records for bin framework search

  1. An adaptive bin framework search method for a beta-sheet protein homopolymer model

    Directory of Open Access Journals (Sweden)

    Hoos Holger H

    2007-04-01

    Full Text Available Abstract Background The problem of protein structure prediction consists of predicting the functional or native structure of a protein given its linear sequence of amino acids. This problem has played a prominent role in the fields of biomolecular physics and algorithm design for over 50 years. Additionally, its importance increases continually as a result of an exponential growth over time in the number of known protein sequences in contrast to a linear increase in the number of determined structures. Our work focuses on the problem of searching an exponentially large space of possible conformations as efficiently as possible, with the goal of finding a global optimum with respect to a given energy function. This problem plays an important role in the analysis of systems with complex search landscapes, and particularly in the context of ab initio protein structure prediction. Results In this work, we introduce a novel approach for solving this conformation search problem based on the use of a bin framework for adaptively storing and retrieving promising locally optimal solutions. Our approach provides a rich and general framework within which a broad range of adaptive or reactive search strategies can be realized. Here, we introduce adaptive mechanisms for choosing which conformations should be stored, based on the set of conformations already stored in memory, and for biasing choices when retrieving conformations from memory in order to overcome search stagnation. Conclusion We show that our bin framework combined with a widely used optimization method, Monte Carlo search, achieves significantly better performance than state-of-the-art generalized ensemble methods for a well-known protein-like homopolymer model on the face-centered cubic lattice.

  2. optBINS: Optimal Binning for histograms

    Science.gov (United States)

    Knuth, Kevin H.

    2018-03-01

    optBINS (optimal binning) determines the optimal number of bins in a uniform bin-width histogram by deriving the posterior probability for the number of bins in a piecewise-constant density model after assigning a multinomial likelihood and a non-informative prior. The maximum of the posterior probability occurs at a point where the prior probability and the the joint likelihood are balanced. The interplay between these opposing factors effectively implements Occam's razor by selecting the most simple model that best describes the data.

  3. Evaluation Framework for Search Instruments

    International Nuclear Information System (INIS)

    Warren, Glen A.; Smith, Leon E.; Cooper, Matt W.; Kaye, William R.

    2005-01-01

    A framework for quantitatively evaluating current and proposed gamma-ray search instrument designs has been developed. The framework is designed to generate a large library of ''virtual neighborhoods'' that can be used to test and evaluate nearly any gamma-ray sensor type. Calculating nuisance-source emissions and combining various sources to create a large number of random virtual scenes places a significant computational burden on the development of the framework. To reduce this burden, a number of radiation transport simplifications have been made which maintain the essential physics ingredients for the quantitative assessment of search instruments while significantly reducing computational times. The various components of the framework, from the simulation and benchmarking of nuisance source emissions to the computational engine for generating the gigabytes of simulated search scenes, are discussed

  4. Combining resummed Higgs predictions across jet bins

    Energy Technology Data Exchange (ETDEWEB)

    Boughezal, Radja [Argonne National Laboratory, IL (United States). High Energy Physics Division; Liu, Xiaohui; Petriello, Frank [Argonne National Laboratory, IL (United States). High Energy Physics Division; Northwestern Univ., Evanston, IL (United States). Dept. of Physics and Astronomy; Tackmann, Frank J. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Walsh, Jonathan R. [California Univ., Berkeley, CA (United States). Ernest Orlando Lawrence Berkeley Laboratory; California Univ., Berkeley, CA (United States). Center for Theoretical Physics

    2013-12-15

    Experimental analyses often use jet binning to distinguish between different kinematic regimes and separate contributions from background processes. To accurately model theoretical uncertainties in these measurements, a consistent description of the jet bins is required. We present a complete framework for the combination of resummed results for production processes in different exclusive jet bins, focusing on Higgs production in gluon fusion as an example. We extend the resummation of the H+1-jet cross section into the challenging low transverse momentum region, lowering the uncertainties considerably. We provide combined predictions with resummation for cross sections in the H+0-jet and H+1-jet bins, and give an improved theory covariance matrix for use in experimental studies. We estimate that the relevant theoretical uncertainties on the signal strength in the H{yields}WW{sup *} analysis are reduced by nearly a factor of 2 compared to the current value.

  5. BIOMedical Search Engine Framework: Lightweight and customized implementation of domain-specific biomedical search engines.

    Science.gov (United States)

    Jácome, Alberto G; Fdez-Riverola, Florentino; Lourenço, Anália

    2016-07-01

    Text mining and semantic analysis approaches can be applied to the construction of biomedical domain-specific search engines and provide an attractive alternative to create personalized and enhanced search experiences. Therefore, this work introduces the new open-source BIOMedical Search Engine Framework for the fast and lightweight development of domain-specific search engines. The rationale behind this framework is to incorporate core features typically available in search engine frameworks with flexible and extensible technologies to retrieve biomedical documents, annotate meaningful domain concepts, and develop highly customized Web search interfaces. The BIOMedical Search Engine Framework integrates taggers for major biomedical concepts, such as diseases, drugs, genes, proteins, compounds and organisms, and enables the use of domain-specific controlled vocabulary. Technologies from the Typesafe Reactive Platform, the AngularJS JavaScript framework and the Bootstrap HTML/CSS framework support the customization of the domain-oriented search application. Moreover, the RESTful API of the BIOMedical Search Engine Framework allows the integration of the search engine into existing systems or a complete web interface personalization. The construction of the Smart Drug Search is described as proof-of-concept of the BIOMedical Search Engine Framework. This public search engine catalogs scientific literature about antimicrobial resistance, microbial virulence and topics alike. The keyword-based queries of the users are transformed into concepts and search results are presented and ranked accordingly. The semantic graph view portraits all the concepts found in the results, and the researcher may look into the relevance of different concepts, the strength of direct relations, and non-trivial, indirect relations. The number of occurrences of the concept shows its importance to the query, and the frequency of concept co-occurrence is indicative of biological relations

  6. Optimizing 4DCBCT projection allocation to respiratory bins

    International Nuclear Information System (INIS)

    O’Brien, Ricky T; Kipritidis, John; Shieh, Chun-Chien; Keall, Paul J

    2014-01-01

    4D cone beam computed tomography (4DCBCT) is an emerging image guidance strategy used in radiotherapy where projections acquired during a scan are sorted into respiratory bins based on the respiratory phase or displacement. 4DCBCT reduces the motion blur caused by respiratory motion but increases streaking artefacts due to projection under-sampling as a result of the irregular nature of patient breathing and the binning algorithms used. For displacement binning the streak artefacts are so severe that displacement binning is rarely used clinically. The purpose of this study is to investigate if sharing projections between respiratory bins and adjusting the location of respiratory bins in an optimal manner can reduce or eliminate streak artefacts in 4DCBCT images. We introduce a mathematical optimization framework and a heuristic solution method, which we will call the optimized projection allocation algorithm, to determine where to position the respiratory bins and which projections to source from neighbouring respiratory bins. Five 4DCBCT datasets from three patients were used to reconstruct 4DCBCT images. Projections were sorted into respiratory bins using equispaced, equal density and optimized projection allocation. The standard deviation of the angular separation between projections was used to assess streaking and the consistency of the segmented volume of a fiducial gold marker was used to assess motion blur. The standard deviation of the angular separation between projections using displacement binning and optimized projection allocation was 30%–50% smaller than conventional phase based binning and 59%–76% smaller than conventional displacement binning indicating more uniformly spaced projections and fewer streaking artefacts. The standard deviation in the marker volume was 20%–90% smaller when using optimized projection allocation than using conventional phase based binning suggesting more uniform marker segmentation and less motion blur. Images

  7. Molecule database framework: a framework for creating database applications with chemical structure search capability.

    Science.gov (United States)

    Kiener, Joos

    2013-12-11

    Research in organic chemistry generates samples of novel chemicals together with their properties and other related data. The involved scientists must be able to store this data and search it by chemical structure. There are commercial solutions for common needs like chemical registration systems or electronic lab notebooks. However for specific requirements of in-house databases and processes no such solutions exist. Another issue is that commercial solutions have the risk of vendor lock-in and may require an expensive license of a proprietary relational database management system. To speed up and simplify the development for applications that require chemical structure search capabilities, I have developed Molecule Database Framework. The framework abstracts the storing and searching of chemical structures into method calls. Therefore software developers do not require extensive knowledge about chemistry and the underlying database cartridge. This decreases application development time. Molecule Database Framework is written in Java and I created it by integrating existing free and open-source tools and frameworks. The core functionality includes:•Support for multi-component compounds (mixtures)•Import and export of SD-files•Optional security (authorization)For chemical structure searching Molecule Database Framework leverages the capabilities of the Bingo Cartridge for PostgreSQL and provides type-safe searching, caching, transactions and optional method level security. Molecule Database Framework supports multi-component chemical compounds (mixtures).Furthermore the design of entity classes and the reasoning behind it are explained. By means of a simple web application I describe how the framework could be used. I then benchmarked this example application to create some basic performance expectations for chemical structure searches and import and export of SD-files. By using a simple web application it was shown that Molecule Database Framework

  8. Generalizing Backtrack-Free Search: A Framework for Search-Free Constraint Satisfaction

    Science.gov (United States)

    Jonsson, Ari K.; Frank, Jeremy

    2000-01-01

    Tractable classes of constraint satisfaction problems are of great importance in artificial intelligence. Identifying and taking advantage of such classes can significantly speed up constraint problem solving. In addition, tractable classes are utilized in applications where strict worst-case performance guarantees are required, such as constraint-based plan execution. In this work, we present a formal framework for search-free (backtrack-free) constraint satisfaction. The framework is based on general procedures, rather than specific propagation techniques, and thus generalizes existing techniques in this area. We also relate search-free problem solving to the notion of decision sets and use the result to provide a constructive criterion that is sufficient to guarantee search-free problem solving.

  9. The grumpy bin

    DEFF Research Database (Denmark)

    Altarriba, Ferran; Funk, Mathias; Lanzani, Stefano Eugenio

    2017-01-01

    Domestic food waste is a world-wide problem that is complex and difficult to tackle as it touches diverse habits and social behaviors. This paper introduces the Grumpy Bin, a smart food waste bin designed for the context of student housing. The Grumpy Bin1 contributes to the state of the art...

  10. Flexible patient information search and retrieval framework: pilot implementation

    Science.gov (United States)

    Erdal, Selnur; Catalyurek, Umit V.; Saltz, Joel; Kamal, Jyoti; Gurcan, Metin N.

    2007-03-01

    Medical centers collect and store significant amount of valuable data pertaining to patients' visit in the form of medical free-text. In addition, standardized diagnosis codes (International Classification of Diseases, Ninth Revision, Clinical Modification: ICD9-CM) related to those dictated reports are usually available. In this work, we have created a framework where image searches could be initiated through a combination of free-text reports as well as ICD9 codes. This framework enables more comprehensive search on existing large sets of patient data in a systematic way. The free text search is enriched by computer-aided inclusion of additional search terms enhanced by a thesaurus. This combination of enriched search allows users to access to a larger set of relevant results from a patient-centric PACS in a simpler way. Therefore, such framework is of particular use in tasks such as gathering images for desired patient populations, building disease models, and so on. As the motivating application of our framework, we implemented a search engine. This search engine processed two years of patient data from the OSU Medical Center's Information Warehouse and identified lung nodule location information using a combination of UMLS Meta-Thesaurus enhanced text report searches along with ICD9 code searches on patients that have been discharged. Five different queries with various ICD9 codes involving lung cancer were carried out on 172552 cases. Each search was completed under a minute on average per ICD9 code and the inclusion of UMLS thesaurus increased the number of relevant cases by 45% on average.

  11. PDE-Foam - a probability-density estimation method using self-adapting phase-space binning

    CERN Document Server

    Dannheim, Dominik; Voigt, Alexander; Grahn, Karl-Johan; Speckmayer, Peter

    2009-01-01

    Probability-Density Estimation (PDE) is a multivariate discrimination technique based on sampling signal and background densities defined by event samples from data or Monte-Carlo (MC) simulations in a multi-dimensional phase space. To efficiently use large event samples to estimate the probability density, a binary search tree (range searching) is used in the PDE-RS implementation. It is a generalisation of standard likelihood methods and a powerful classification tool for problems with highly non-linearly correlated observables. In this paper, we present an innovative improvement of the PDE method that uses a self-adapting binning method to divide the multi-dimensional phase space in a finite number of hyper-rectangles (cells). The binning algorithm adjusts the size and position of a predefined number of cells inside the multidimensional phase space, minimizing the variance of the signal and background densities inside the cells. The binned density information is stored in binary trees, allowing for a very ...

  12. MaxBin 2.0: an automated binning algorithm to recover genomes from multiple metagenomic datasets

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Yu-Wei [Joint BioEnergy Inst. (JBEI), Emeryville, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Simmons, Blake A. [Joint BioEnergy Inst. (JBEI), Emeryville, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Singer, Steven W. [Joint BioEnergy Inst. (JBEI), Emeryville, CA (United States); Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States)

    2015-10-29

    The recovery of genomes from metagenomic datasets is a critical step to defining the functional roles of the underlying uncultivated populations. We previously developed MaxBin, an automated binning approach for high-throughput recovery of microbial genomes from metagenomes. Here, we present an expanded binning algorithm, MaxBin 2.0, which recovers genomes from co-assembly of a collection of metagenomic datasets. Tests on simulated datasets revealed that MaxBin 2.0 is highly accurate in recovering individual genomes, and the application of MaxBin 2.0 to several metagenomes from environmental samples demonstrated that it could achieve two complementary goals: recovering more bacterial genomes compared to binning a single sample as well as comparing the microbial community composition between different sampling environments. Availability and implementation: MaxBin 2.0 is freely available at http://sourceforge.net/projects/maxbin/ under BSD license. Supplementary information: Supplementary data are available at Bioinformatics online.

  13. The Maximum Resource Bin Packing Problem

    DEFF Research Database (Denmark)

    Boyar, J.; Epstein, L.; Favrholdt, L.M.

    2006-01-01

    Usually, for bin packing problems, we try to minimize the number of bins used or in the case of the dual bin packing problem, maximize the number or total size of accepted items. This paper presents results for the opposite problems, where we would like to maximize the number of bins used...... algorithms, First-Fit-Increasing and First-Fit-Decreasing for the maximum resource variant of classical bin packing. For the on-line variant, we define maximum resource variants of classical and dual bin packing. For dual bin packing, no on-line algorithm is competitive. For classical bin packing, we find...

  14. Radio Frequency Identification (RFID) and communication technologies for solid waste bin and truck monitoring system.

    Science.gov (United States)

    Hannan, M A; Arebey, Maher; Begum, R A; Basri, Hassan

    2011-12-01

    This paper deals with a system of integration of Radio Frequency Identification (RFID) and communication technologies for solid waste bin and truck monitoring system. RFID, GPS, GPRS and GIS along with camera technologies have been integrated and developed the bin and truck intelligent monitoring system. A new kind of integrated theoretical framework, hardware architecture and interface algorithm has been introduced between the technologies for the successful implementation of the proposed system. In this system, bin and truck database have been developed such a way that the information of bin and truck ID, date and time of waste collection, bin status, amount of waste and bin and truck GPS coordinates etc. are complied and stored for monitoring and management activities. The results showed that the real-time image processing, histogram analysis, waste estimation and other bin information have been displayed in the GUI of the monitoring system. The real-time test and experimental results showed that the performance of the developed system was stable and satisfied the monitoring system with high practicability and validity. Copyright © 2011 Elsevier Ltd. All rights reserved.

  15. A Framework to Develop Persuasive Smart Environments

    Science.gov (United States)

    Lobo, Pedro; Romão, Teresa; Dias, A. Eduardo; Danado, José Carlos

    This paper presents a framework for the creation of context-sensitive persuasive applications. The framework allows the authoring of new persuasive smart environments producing the appropriate feedback to the users based on different sensors spread throughout the environment to capture contextual information. Using this framework, we created an application, Smart Bins, aimed at promoting users' behavioural changes regarding the recycling of waste materials. Furthermore, to evaluate the usability of our authoring tool, we performed user tests to analyze if developers could successfully create the Smart Bins application using the framework. A description of the Smart Bins application, as well as the results of the user tests, are also presented in this paper.

  16. Consistency Check for the Bin Packing Constraint Revisited

    Science.gov (United States)

    Dupuis, Julien; Schaus, Pierre; Deville, Yves

    The bin packing problem (BP) consists in finding the minimum number of bins necessary to pack a set of items so that the total size of the items in each bin does not exceed the bin capacity C. The bin capacity is common for all the bins.

  17. Mohammed A Bin Hussain

    Indian Academy of Sciences (India)

    Home; Journals; Bulletin of Materials Science. Mohammed A Bin Hussain. Articles written in Bulletin of Materials Science. Volume 38 Issue 7 December 2015 pp 1731-1736. Sintered gahnite–cordierite glass-ceramic based on raw materials with different fluorine sources · Esmat M A Hamzawy Mohammed A Bin Hussain.

  18. COCACOLA: binning metagenomic contigs using sequence COmposition, read CoverAge, CO-alignment and paired-end read LinkAge.

    Science.gov (United States)

    Lu, Yang Young; Chen, Ting; Fuhrman, Jed A; Sun, Fengzhu

    2017-03-15

    The advent of next-generation sequencing technologies enables researchers to sequence complex microbial communities directly from the environment. Because assembly typically produces only genome fragments, also known as contigs, instead of an entire genome, it is crucial to group them into operational taxonomic units (OTUs) for further taxonomic profiling and down-streaming functional analysis. OTU clustering is also referred to as binning. We present COCACOLA, a general framework automatically bin contigs into OTUs based on sequence composition and coverage across multiple samples. The effectiveness of COCACOLA is demonstrated in both simulated and real datasets in comparison with state-of-art binning approaches such as CONCOCT, GroopM, MaxBin and MetaBAT. The superior performance of COCACOLA relies on two aspects. One is using L 1 distance instead of Euclidean distance for better taxonomic identification during initialization. More importantly, COCACOLA takes advantage of both hard clustering and soft clustering by sparsity regularization. In addition, the COCACOLA framework seamlessly embraces customized knowledge to facilitate binning accuracy. In our study, we have investigated two types of additional knowledge, the co-alignment to reference genomes and linkage of contigs provided by paired-end reads, as well as the ensemble of both. We find that both co-alignment and linkage information further improve binning in the majority of cases. COCACOLA is scalable and faster than CONCOCT, GroopM, MaxBin and MetaBAT. The software is available at https://github.com/younglululu/COCACOLA . fsun@usc.edu. Supplementary data are available at Bioinformatics online. © The Author 2016. Published by Oxford University Press. All rights reserved. For Permissions, please e-mail: journals.permissions@oup.com

  19. Signal Region Optimisation Studies Based on BDT and Multi-Bin Approaches in the Context of Supersymmetry Searches in Hadronic Final States with the ATLAS Detector

    CERN Document Server

    AUTHOR|(CDS)2097636; Makovec, Nikola; Rúriková, Zuzana

    The searches for supersymmetric phenomena are mostly based on simple Cut & Count methods. One example is the search for squarks and gluinos in final states with multiple jets, missing transverse momentum and without leptons. This analysis, based on $36.1\\,\\text{fb}^{−1}$ of $pp$ collision data at $\\sqrt{s}$ = 13 TeV recorded with the ATLAS detector, uses Cut & Count based methods in the signal regions. In order to improve the analysis sensitivity, the use of sophisticated techniques, such as boosted decision trees (BDT) and Multi-Bin, is being investigated in this thesis. The focus of the study lies on squarks and gluino searches. These techniques are evaluated using Monte Carlo simulation. The goal is to find a new approach which is on the one hand simple but allows for a significant improvement. A gain up to approximately 200 GeV in the neutralino mass and an enhancement of about 200 GeV in the squark and gluino mass is achieved with these new techniques.

  20. Bin mode estimation methods for Compton camera imaging

    International Nuclear Information System (INIS)

    Ikeda, S.; Odaka, H.; Uemura, M.; Takahashi, T.; Watanabe, S.; Takeda, S.

    2014-01-01

    We study the image reconstruction problem of a Compton camera which consists of semiconductor detectors. The image reconstruction is formulated as a statistical estimation problem. We employ a bin-mode estimation (BME) and extend an existing framework to a Compton camera with multiple scatterers and absorbers. Two estimation algorithms are proposed: an accelerated EM algorithm for the maximum likelihood estimation (MLE) and a modified EM algorithm for the maximum a posteriori (MAP) estimation. Numerical simulations demonstrate the potential of the proposed methods

  1. PALNS - A software framework for parallel large neighborhood search

    DEFF Research Database (Denmark)

    Røpke, Stefan

    2009-01-01

    This paper propose a simple, parallel, portable software framework for the metaheuristic named large neighborhood search (LNS). The aim is to provide a framework where the user has to set up a few data structures and implement a few functions and then the framework provides a metaheuristic where ...... parallelization "comes for free". We apply the parallel LNS heuristic to two different problems: the traveling salesman problem with pickup and delivery (TSPPD) and the capacitated vehicle routing problem (CVRP)....

  2. SPHINX--an algorithm for taxonomic binning of metagenomic sequences.

    Science.gov (United States)

    Mohammed, Monzoorul Haque; Ghosh, Tarini Shankar; Singh, Nitin Kumar; Mande, Sharmila S

    2011-01-01

    Compared with composition-based binning algorithms, the binning accuracy and specificity of alignment-based binning algorithms is significantly higher. However, being alignment-based, the latter class of algorithms require enormous amount of time and computing resources for binning huge metagenomic datasets. The motivation was to develop a binning approach that can analyze metagenomic datasets as rapidly as composition-based approaches, but nevertheless has the accuracy and specificity of alignment-based algorithms. This article describes a hybrid binning approach (SPHINX) that achieves high binning efficiency by utilizing the principles of both 'composition'- and 'alignment'-based binning algorithms. Validation results with simulated sequence datasets indicate that SPHINX is able to analyze metagenomic sequences as rapidly as composition-based algorithms. Furthermore, the binning efficiency (in terms of accuracy and specificity of assignments) of SPHINX is observed to be comparable with results obtained using alignment-based algorithms. A web server for the SPHINX algorithm is available at http://metagenomics.atc.tcs.com/SPHINX/.

  3. Efficient use of design-based binning methodology in a DRAM fab

    Science.gov (United States)

    Karsenti, Laurent; Wehner, Arno; Fischer, Andreas; Seifert, Uwe; Goeckeritz, Jens; Geshel, Mark; Gscheidlen, Dieter; Bartov, Avishai

    2009-03-01

    It is a well established fact that as design rules and printed features shrink, sophisticated techniques are required to ensure the design intent is indeed printed on the wafer. Techniques of this kind are Optical Proximity Correction (OPC), Resolution Enhancement Techniques (RET) and DFM Design for Manufacturing (DFM). As these methods are applied to the overall chip and rely on complex modeling and simulations, they increase the risk of creating local areas or layouts with a limiting process window. Hence, it is necessary to verify the manufacturability (sufficient depth of focus) of the overall die and not only of a pre-defined set of metrology structures. The verification process is commonly based on full chip defect density inspection of a Focus Exposure Matrix (FEM) wafer, combined with appropriate post processing of the inspection data. This is necessary to avoid time consuming search for the Defects of Interest (DOI's) as defect counts are usually too high to be handled by manual SEM review. One way to post process defect density data is the so called design based binning (DBB). The Litho Qualification Monitor (LQM) system allows to classify and also to bin defects based on design information. In this paper we will present an efficient way to combine classification and binning in order to check design rules and to determine the marginal features (layout with low depth of focus). The Design Based Binning has been connected to the Yield Management System (YMS) to allow new process monitoring approaches towards Design Based SPC. This could dramatically cut the time to detect systematic defects inline.

  4. Integrality gap analysis for bin packing games

    NARCIS (Netherlands)

    Kern, Walter; Qui, X.

    A cooperative bin packing game is an $N$-person game, where the player set $N$ consists of $k$ bins of capacity 1 each and $n$ items of sizes $a_1,\\dots,a_n$. The value $v(S)$ of a coalition $S$ of players is defined to be the maximum total size of items in $S$ that can be packed into the bins of

  5. Design and Development of a Smart Waste Bin

    Directory of Open Access Journals (Sweden)

    Michael E.

    2017-10-01

    Full Text Available For years waste bin has been part of our lives this has necessitated many inventions and innovations to make it automated. In this light much research was channeled towards the opening and closing of the bin when the presence of human is sensed. However this may be considered less smart since the bin will operate when the presence of human is sensed even though there is no intention to use it. To avert this ill this paper presents the design and development of a smart waste bin. The objective of this paper is to develop a smart waste bin that detects the presence of man at a particular distance 1 meter for usage so as not to spill the dirt and obeys voice command to open or close the lid. This is achieved by the use of PIR ultrasonic module voice recognition module Arduino and servo motor. Results gotten after testing the developed system shows that the performance of the waste bin attains a better level of smartness compared to existing waste bin.

  6. Improved Taxation Rate for Bin Packing Games

    Science.gov (United States)

    Kern, Walter; Qiu, Xian

    A cooperative bin packing game is a N-person game, where the player set N consists of k bins of capacity 1 each and n items of sizes a 1, ⋯ ,a n . The value of a coalition of players is defined to be the maximum total size of items in the coalition that can be packed into the bins of the coalition. We present an alternative proof for the non-emptiness of the 1/3-core for all bin packing games and show how to improve this bound ɛ= 1/3 (slightly). We conjecture that the true best possible value is ɛ= 1/7.

  7. Sorting, Searching, and Simulation in the MapReduce Framework

    DEFF Research Database (Denmark)

    Goodrich, Michael T.; Sitchinava, Nodar; Zhang, Qin

    2011-01-01

    We study the MapReduce framework from an algorithmic standpoint, providing a generalization of the previous algorithmic models for MapReduce. We present optimal solutions for the fundamental problems of all-prefix-sums, sorting and multi-searching. Additionally, we design optimal simulations...

  8. TH-E-17A-05: Optimizing Four Dimensional Cone Beam Computed Tomography Projection Allocation to Respiratory Bins

    International Nuclear Information System (INIS)

    OBrien, R; Shieh, C; Kipritidis, J; Keall, P

    2014-01-01

    Purpose: Four dimensional cone beam computed tomography (4DCBCT) is an emerging image guidance strategy but it can suffer from poor image quality. To avoid repeating scans it is beneficial to make the best use of the imaging data obtained. For conventional 4DCBCT the location and size of respiratory bins is fixed and projections are allocated to the respiratory bin within which it falls. Strictly adhering to this rule is unnecessary and can compromise image quality. In this study we optimize the size and location of respiratory bins and allow projections to be sourced from adjacent phases of the respiratory cycle. Methods: A mathematical optimization framework using mixed integer quadratic programming has been developed that determines when to source projections from adjacent respiratory bins and optimizes the size and location of the bins. The method, which we will call projection sharing, runs in under 2 seconds of CPU time. Five 4DCBCT datasets of stage III-IV lung cancer patients were used to test the algorithm. The standard deviation of the angular separation between projections (SD-A) and the standard deviation in the volume of the reconstructed fiducial gold coil (SD-V) were used as proxies to measure streaking artefacts and motion blur respectively. Results: The SD-A using displacement binning and projection sharing was 30%–50% smaller than conventional phase based binning and 59%–76% smaller than conventional displacement binning indicating more uniformly spaced projections and fewer streaking artefacts. The SD-V was 20–90% smaller when using projection sharing than using conventional phase based binning suggesting more uniform marker segmentation and less motion blur. Conclusion: Image quality was visibly and significantly improved with projection sharing. Projection sharing does not require any modifications to existing hardware and offers a more robust replacement to phase based binning, or, an option if phase based reconstruction is not of a

  9. Efficient binning for bitmap indices on high-cardinality attributes

    Energy Technology Data Exchange (ETDEWEB)

    Rotem, Doron; Stockinger, Kurt; Wu, Kesheng

    2004-11-17

    Bitmap indexing is a common technique for indexing high-dimensional data in data warehouses and scientific applications. Though efficient for low-cardinality attributes, query processing can be rather costly for high-cardinality attributes due to the large storage requirements for the bitmap indices. Binning is a common technique for reducing storage costs of bitmap indices. This technique partitions the attribute values into a number of ranges, called bins, and uses bitmap vectors to represent bins (attribute ranges) rather than distinct values. Although binning may reduce storage costs, it may increase the access costs of queries that do not fall on exact bin boundaries (edge bins). For this kind of queries the original data values associated with edge bins must be accessed, in order to check them against the query constraints.In this paper we study the problem of finding optimal locations for the bin boundaries in order to minimize these access costs subject to storage constraints. We propose a dynamic programming algorithm for optimal partitioning of attribute values into bins that takes into account query access patterns as well as data distribution statistics. Mathematical analysis and experiments on real life data sets show that the optimal partitioning achieved by this algorithm can lead to a significant improvement in the access costs of bitmap indexing systems for high-cardinality attributes.

  10. Bin Set 1 Calcine Retrieval Feasibility Study

    International Nuclear Information System (INIS)

    Adams, R.D.; Berry, S.M.; Galloway, K.J.; Langenwalter, T.A.; Lopez, D.A.; Noakes, C.M.; Peterson, H.K.; Pope, M.I.; Turk, R.J.

    1999-01-01

    At the Department of Energy's Idaho Nuclear Technology and Engineering Center, as an interim waste management measure, both mixed high-level liquid waste and sodium bearing waste have been solidified by a calculation process and are stored in the Calcine Solids Storage Facilities. This calcined product will eventually be treated to allow final disposal in a national geologic repository. The Calcine Solids Storage Facilities comprise seven ''bit sets.'' Bin Set 1, the first to be constructed, was completed in 1959, and has been in service since 1963. It is the only bin set that does not meet current safe-shutdown earthquake seismic criteria. In addition, it is the only bin set that lacks built-in features to aid in calcine retrieval. One option to alleviate the seismic compliance issue is to transport the calcine from Bin Set 1 to another bin set which has the required capacity and which is seismically qualified. This report studies the feasibility of retrieving the calcine from Bi n Set 1 and transporting it into Bin Set 6 which is located approximately 650 feet away. Because Bin Set 1 was not designed for calcine retrieval, and because of the high radiation levels and potential contamination spread from the calcined material, this is a challenging engineering task. This report presents preconceptual design studies for remotely-operated, low-density, pneumatic vacuum retrieval and transport systems and equipment that are based on past work performed by the Raytheon Engineers and Constructors architectural engineering firm. The designs presented are considered feasible; however, future development work will be needed in several areas during the subsequent conceptual design phase

  11. Bin Set 1 Calcine Retrieval Feasibility Study

    Energy Technology Data Exchange (ETDEWEB)

    R. D. Adams; S. M. Berry; K. J. Galloway; T. A. Langenwalter; D. A. Lopez; C. M. Noakes; H. K. Peterson; M. I. Pope; R. J. Turk

    1999-10-01

    At the Department of Energy's Idaho Nuclear Technology and Engineering Center, as an interim waste management measure, both mixed high-level liquid waste and sodium bearing waste have been solidified by a calculation process and are stored in the Calcine Solids Storage Facilities. This calcined product will eventually be treated to allow final disposal in a national geologic repository. The Calcine Solids Storage Facilities comprise seven ''bit sets.'' Bin Set 1, the first to be constructed, was completed in 1959, and has been in service since 1963. It is the only bin set that does not meet current safe-shutdown earthquake seismic criteria. In addition, it is the only bin set that lacks built-in features to aid in calcine retrieval. One option to alleviate the seismic compliance issue is to transport the calcine from Bin Set 1 to another bin set which has the required capacity and which is seismically qualified. This report studies the feasibility of retrieving the calcine from Bi n Set 1 and transporting it into Bin Set 6 which is located approximately 650 feet away. Because Bin Set 1 was not designed for calcine retrieval, and because of the high radiation levels and potential contamination spread from the calcined material, this is a challenging engineering task. This report presents preconceptual design studies for remotely-operated, low-density, pneumatic vacuum retrieval and transport systems and equipment that are based on past work performed by the Raytheon Engineers and Constructors architectural engineering firm. The designs presented are considered feasible; however, future development work will be needed in several areas during the subsequent conceptual design phase.

  12. Bioinformatics and Astrophysics Cluster (BinAc)

    Science.gov (United States)

    Krüger, Jens; Lutz, Volker; Bartusch, Felix; Dilling, Werner; Gorska, Anna; Schäfer, Christoph; Walter, Thomas

    2017-09-01

    BinAC provides central high performance computing capacities for bioinformaticians and astrophysicists from the state of Baden-Württemberg. The bwForCluster BinAC is part of the implementation concept for scientific computing for the universities in Baden-Württemberg. Community specific support is offered through the bwHPC-C5 project.

  13. Multifractal diffusion entropy analysis: Optimal bin width of probability histograms

    Science.gov (United States)

    Jizba, Petr; Korbel, Jan

    2014-11-01

    In the framework of Multifractal Diffusion Entropy Analysis we propose a method for choosing an optimal bin-width in histograms generated from underlying probability distributions of interest. The method presented uses techniques of Rényi’s entropy and the mean squared error analysis to discuss the conditions under which the error in the multifractal spectrum estimation is minimal. We illustrate the utility of our approach by focusing on a scaling behavior of financial time series. In particular, we analyze the S&P500 stock index as sampled at a daily rate in the time period 1950-2013. In order to demonstrate a strength of the method proposed we compare the multifractal δ-spectrum for various bin-widths and show the robustness of the method, especially for large values of q. For such values, other methods in use, e.g., those based on moment estimation, tend to fail for heavy-tailed data or data with long correlations. Connection between the δ-spectrum and Rényi’s q parameter is also discussed and elucidated on a simple example of multiscale time series.

  14. BinQuasi: a peak detection method for ChIP-sequencing data with biological replicates.

    Science.gov (United States)

    Goren, Emily; Liu, Peng; Wang, Chao; Wang, Chong

    2018-04-19

    ChIP-seq experiments that are aimed at detecting DNA-protein interactions require biological replication to draw inferential conclusions, however there is no current consensus on how to analyze ChIP-seq data with biological replicates. Very few methodologies exist for the joint analysis of replicated ChIP-seq data, with approaches ranging from combining the results of analyzing replicates individually to joint modeling of all replicates. Combining the results of individual replicates analyzed separately can lead to reduced peak classification performance compared to joint modeling. Currently available methods for joint analysis may fail to control the false discovery rate at the nominal level. We propose BinQuasi, a peak caller for replicated ChIP-seq data, that jointly models biological replicates using a generalized linear model framework and employs a one-sided quasi-likelihood ratio test to detect peaks. When applied to simulated data and real datasets, BinQuasi performs favorably compared to existing methods, including better control of false discovery rate than existing joint modeling approaches. BinQuasi offers a flexible approach to joint modeling of replicated ChIP-seq data which is preferable to combining the results of replicates analyzed individually. Source code is freely available for download at https://cran.r-project.org/package=BinQuasi, implemented in R. pliu@iastate.edu or egoren@iastate.edu. Supplementary material is available at Bioinformatics online.

  15. Soft-collinear factorization and zero-bin subtractions

    International Nuclear Information System (INIS)

    Chiu Juiyu; Fuhrer, Andreas; Kelley, Randall; Manohar, Aneesh V.; Hoang, Andre H.

    2009-01-01

    We study the Sudakov form factor for a spontaneously broken gauge theory using a (new) Δ-regulator. To be well defined, the effective theory requires zero-bin subtractions for the collinear sectors. The zero-bin subtractions depend on the gauge boson mass M and are not scaleless. They have both finite and 1/ε contributions and are needed to give the correct anomalous dimension and low-scale matching contributions. We also demonstrate the necessity of zero-bin subtractions for soft-collinear factorization. We find that after zero-bin subtractions the form factor is the sum of the collinear contributions minus a soft mass-mode contribution, in agreement with a previous result of Idilbi and Mehen in QCD. This appears to conflict with the method-of-regions approach, where one gets the sum of contributions from different regions.

  16. Implementation of Bin Packing Model for Reed Switch Production Planning

    Energy Technology Data Exchange (ETDEWEB)

    Parra, Rainier Romero [Polytechnic University of Baja California, Calle de la Claridad S/N, Col Plutarco Elias Calles, Mexicali, B. C., 21376 (Mexico); Burtseva, Larysa [Engineering Institute, Autonomous University of Baja California, Calle de la Normal S/N, Col. Insurgentes Este, Mexicali, BC, 21280 (Mexico)

    2010-06-17

    This paper presents a form to resolve a real problem of efficient material election in reed switch manufacturing. The carrying out of the consumer demands depends on the stochastic results of the classification process where each lot of switches is distributed into bins according to an electric measure value. Various glass types are employed for the switch manufacturing. The effect caused by the glass type variation on the switch classification results was investigated. Based on real data statistic analysis, the problem is reduced to the lot number minimizing taking into consideration the glass type, and interpreted as a bin packing problem generalization. On difference to the classic bin packing problem, in the considered case, an item represents a set of pieces; a container is divided into a number of bins (sub-containers); the bin capacity is variable; there are the assignment restrictions between bins and sets of pieces; the items are allowed to be fragmented into bins and containers. The problem has a high complexity. A heuristic offline algorithm is proposed to find the quantity, types and packing sequence of containers, the item fragments associated with containers and bins. The bin capacities do not affect the algorithm.

  17. Implementation of Bin Packing Model for Reed Switch Production Planning

    International Nuclear Information System (INIS)

    Parra, Rainier Romero; Burtseva, Larysa

    2010-01-01

    This paper presents a form to resolve a real problem of efficient material election in reed switch manufacturing. The carrying out of the consumer demands depends on the stochastic results of the classification process where each lot of switches is distributed into bins according to an electric measure value. Various glass types are employed for the switch manufacturing. The effect caused by the glass type variation on the switch classification results was investigated. Based on real data statistic analysis, the problem is reduced to the lot number minimizing taking into consideration the glass type, and interpreted as a bin packing problem generalization. On difference to the classic bin packing problem, in the considered case, an item represents a set of pieces; a container is divided into a number of bins (sub-containers); the bin capacity is variable; there are the assignment restrictions between bins and sets of pieces; the items are allowed to be fragmented into bins and containers. The problem has a high complexity. A heuristic offline algorithm is proposed to find the quantity, types and packing sequence of containers, the item fragments associated with containers and bins. The bin capacities do not affect the algorithm.

  18. Segmentation and Location Computation of Bin Objects

    Directory of Open Access Journals (Sweden)

    C.R. Hema

    2008-11-01

    Full Text Available In this paper we present a stereo vision based system for segmentation and location computation of partially occluded objects in bin picking environments. Algorithms to segment partially occluded objects and to find the object location [midpoint,x, y and z coordinates] with respect to the bin area are proposed. The z co ordinate is computed using stereo images and neural networks. The proposed algorithms is tested using two neural network architectures namely the Radial Basis Function nets and Simple Feedforward nets. The training results fo feedforward nets are found to be more suitable for the current application.The proposed stereo vision system is interfaced with an Adept SCARA Robot to perform bin picking operations. The vision system is found to be effective for partially occluded objects, in the absence of albedo effects. The results are validated through real time bin picking experiments on the Adept Robot.

  19. Refractory bin for burning

    Energy Technology Data Exchange (ETDEWEB)

    McPherson, D.L.; McPherson, T.L.

    1989-12-26

    This patent describes a refractory bin. It has a generally rectangular horizontal cross sectional configuration. It has wall structures each comprising an upper and a lower pair of elongated horizontal vertically spaced generally parallel support beams each having a vertical flange defining a support edge along its upper surface, a first generally rectangular refractory panel arranged with its lower edge at the bottom of the bin and with its outer surface in flat face contacting relation with the vertical flanges of the lower pair of support beams, a plurality of brackets each having a horizontal part and a vertical part and being secured to the outer surface of the first refractory panel.

  20. Sorting, Searching, and Simulation in the MapReduce Framework

    DEFF Research Database (Denmark)

    Goodrich, Michael T.; Sitchinava, Nodari; Zhang, Qin

    2011-01-01

    usefulness of our approach by designing and analyzing efficient MapReduce algorithms for fundamental sorting, searching, and simulation problems. This study is motivated by a goal of ultimately putting the MapReduce framework on an equal theoretical footing with the well-known PRAM and BSP parallel...... in parallel computational geometry for the MapReduce framework, which result in efficient MapReduce algorithms for sorting, 2- and 3-dimensional convex hulls, and fixed-dimensional linear programming. For the case when mappers and reducers have a memory/message-I/O size of M = (N), for a small constant > 0...

  1. The volatile compound BinBase mass spectral database.

    Science.gov (United States)

    Skogerson, Kirsten; Wohlgemuth, Gert; Barupal, Dinesh K; Fiehn, Oliver

    2011-08-04

    Volatile compounds comprise diverse chemical groups with wide-ranging sources and functions. These compounds originate from major pathways of secondary metabolism in many organisms and play essential roles in chemical ecology in both plant and animal kingdoms. In past decades, sampling methods and instrumentation for the analysis of complex volatile mixtures have improved; however, design and implementation of database tools to process and store the complex datasets have lagged behind. The volatile compound BinBase (vocBinBase) is an automated peak annotation and database system developed for the analysis of GC-TOF-MS data derived from complex volatile mixtures. The vocBinBase DB is an extension of the previously reported metabolite BinBase software developed to track and identify derivatized metabolites. The BinBase algorithm uses deconvoluted spectra and peak metadata (retention index, unique ion, spectral similarity, peak signal-to-noise ratio, and peak purity) from the Leco ChromaTOF software, and annotates peaks using a multi-tiered filtering system with stringent thresholds. The vocBinBase algorithm assigns the identity of compounds existing in the database. Volatile compound assignments are supported by the Adams mass spectral-retention index library, which contains over 2,000 plant-derived volatile compounds. Novel molecules that are not found within vocBinBase are automatically added using strict mass spectral and experimental criteria. Users obtain fully annotated data sheets with quantitative information for all volatile compounds for studies that may consist of thousands of chromatograms. The vocBinBase database may also be queried across different studies, comprising currently 1,537 unique mass spectra generated from 1.7 million deconvoluted mass spectra of 3,435 samples (18 species). Mass spectra with retention indices and volatile profiles are available as free download under the CC-BY agreement (http://vocbinbase.fiehnlab.ucdavis.edu). The Bin

  2. The volatile compound BinBase mass spectral database

    Directory of Open Access Journals (Sweden)

    Barupal Dinesh K

    2011-08-01

    Full Text Available Abstract Background Volatile compounds comprise diverse chemical groups with wide-ranging sources and functions. These compounds originate from major pathways of secondary metabolism in many organisms and play essential roles in chemical ecology in both plant and animal kingdoms. In past decades, sampling methods and instrumentation for the analysis of complex volatile mixtures have improved; however, design and implementation of database tools to process and store the complex datasets have lagged behind. Description The volatile compound BinBase (vocBinBase is an automated peak annotation and database system developed for the analysis of GC-TOF-MS data derived from complex volatile mixtures. The vocBinBase DB is an extension of the previously reported metabolite BinBase software developed to track and identify derivatized metabolites. The BinBase algorithm uses deconvoluted spectra and peak metadata (retention index, unique ion, spectral similarity, peak signal-to-noise ratio, and peak purity from the Leco ChromaTOF software, and annotates peaks using a multi-tiered filtering system with stringent thresholds. The vocBinBase algorithm assigns the identity of compounds existing in the database. Volatile compound assignments are supported by the Adams mass spectral-retention index library, which contains over 2,000 plant-derived volatile compounds. Novel molecules that are not found within vocBinBase are automatically added using strict mass spectral and experimental criteria. Users obtain fully annotated data sheets with quantitative information for all volatile compounds for studies that may consist of thousands of chromatograms. The vocBinBase database may also be queried across different studies, comprising currently 1,537 unique mass spectra generated from 1.7 million deconvoluted mass spectra of 3,435 samples (18 species. Mass spectra with retention indices and volatile profiles are available as free download under the CC-BY agreement (http

  3. Corrosion monitoring of storage bins for radioactive calcines

    International Nuclear Information System (INIS)

    Hoffman, T.L.

    1975-01-01

    Highly radioactive liquid waste produced at the Idaho Chemical Processing Plant is calcined to a granular solid for long term storage in stainless steel bins. Corrosion evaluation of coupons withdrawn from these bins indicates excellent performance for the materials of construction of the bins. At exposure periods of up to six years the average penetration rates are 0.01 and 0.05 mils per year for Types 304 and 405 stainless steels, respectively. (auth)

  4. Fast Search and Adaptive Resolution for Complex Particle Kinetics

    Science.gov (United States)

    Larson, David J.

    2005-10-01

    A new plasma simulation algorithm, intended to bridge the gap between Eulerian fluid and kinetic regimes, is now being used for a variety of applications in ICF and weapon effects. The CPK method (Complex Particle Kinetic) concept [1] uses an ensemble of macro-particles with a Gaussian spatial profile and a Mawellian velocity distribution to represent particle distributions in phase space. Time evolution is modeled by a combination of Lagrangian motion and internal evolution within each individual macro-particle. Collisional particle-particle interactions [2] are facilitated by sorting particles into bins depending of the particle size. Different bin levels are connected by a linked list. Searching for neighboring particles is highly efficient because the search is limited to particles in neighboring bins with the possibility of interaction. The bin structure also allows the computation of various spatial moments at different resolutions. Combining the results of the moment calculations yields information on where and when increased resolution is necessary. We will present details of the particle binning process along with progress towards our goal of simulating the transition from continuum to fully kinetic physics. [1] D. W. Hewett, J. Comp. Phys. 189 (2003). [2] D. J. Larson, J. Comp. Phys. 188 (2003).

  5. ISART: A Generic Framework for Searching Books with Social Information.

    Science.gov (United States)

    Yin, Xu-Cheng; Zhang, Bo-Wen; Cui, Xiao-Ping; Qu, Jiao; Geng, Bin; Zhou, Fang; Song, Li; Hao, Hong-Wei

    2016-01-01

    Effective book search has been discussed for decades and is still future-proof in areas as diverse as computer science, informatics, e-commerce and even culture and arts. A variety of social information contents (e.g, ratings, tags and reviews) emerge with the huge number of books on the Web, but how they are utilized for searching and finding books is seldom investigated. Here we develop an Integrated Search And Recommendation Technology (IsArt), which breaks new ground by providing a generic framework for searching books with rich social information. IsArt comprises a search engine to rank books with book contents and professional metadata, a Generalized Content-based Filtering model to thereafter rerank books with user-generated social contents, and a learning-to-rank technique to finally combine a wide range of diverse reranking results. Experiments show that this technology permits embedding social information to promote book search effectiveness, and IsArt, by making use of it, has the best performance on CLEF/INEX Social Book Search Evaluation datasets of all 4 years (from 2011 to 2014), compared with some other state-of-the-art methods.

  6. Solar Radiation Pressure Binning for the Geosynchronous Orbit

    Science.gov (United States)

    Hejduk, M. D.; Ghrist, R. W.

    2011-01-01

    Orbital maintenance parameters for individual satellites or groups of satellites have traditionally been set by examining orbital parameters alone, such as through apogee and perigee height binning; this approach ignored the other factors that governed an individual satellite's susceptibility to non-conservative forces. In the atmospheric drag regime, this problem has been addressed by the introduction of the "energy dissipation rate," a quantity that represents the amount of energy being removed from the orbit; such an approach is able to consider both atmospheric density and satellite frontal area characteristics and thus serve as a mechanism for binning satellites of similar behavior. The geo-synchronous orbit (of broader definition than the geostationary orbit -- here taken to be from 1300 to 1800 minutes in orbital period) is not affected by drag; rather, its principal non-conservative force is that of solar radiation pressure -- the momentum imparted to the satellite by solar radiometric energy. While this perturbation is solved for as part of the orbit determination update, no binning or division scheme, analogous to the drag regime, has been developed for the geo-synchronous orbit. The present analysis has begun such an effort by examining the behavior of geosynchronous rocket bodies and non-stabilized payloads as a function of solar radiation pressure susceptibility. A preliminary examination of binning techniques used in the drag regime gives initial guidance regarding the criteria for useful bin divisions. Applying these criteria to the object type, solar radiation pressure, and resultant state vector accuracy for the analyzed dataset, a single division of "large" satellites into two bins for the purposes of setting related sensor tasking and orbit determination (OD) controls is suggested. When an accompanying analysis of high area-to-mass objects is complete, a full set of binning recommendations for the geosynchronous orbit will be available.

  7. Bin Ratio-Based Histogram Distances and Their Application to Image Classification.

    Science.gov (United States)

    Hu, Weiming; Xie, Nianhua; Hu, Ruiguang; Ling, Haibin; Chen, Qiang; Yan, Shuicheng; Maybank, Stephen

    2014-12-01

    Large variations in image background may cause partial matching and normalization problems for histogram-based representations, i.e., the histograms of the same category may have bins which are significantly different, and normalization may produce large changes in the differences between corresponding bins. In this paper, we deal with this problem by using the ratios between bin values of histograms, rather than bin values' differences which are used in the traditional histogram distances. We propose a bin ratio-based histogram distance (BRD), which is an intra-cross-bin distance, in contrast with previous bin-to-bin distances and cross-bin distances. The BRD is robust to partial matching and histogram normalization, and captures correlations between bins with only a linear computational complexity. We combine the BRD with the ℓ1 histogram distance and the χ(2) histogram distance to generate the ℓ1 BRD and the χ(2) BRD, respectively. These combinations exploit and benefit from the robustness of the BRD under partial matching and the robustness of the ℓ1 and χ(2) distances to small noise. We propose a method for assessing the robustness of histogram distances to partial matching. The BRDs and logistic regression-based histogram fusion are applied to image classification. The experimental results on synthetic data sets show the robustness of the BRDs to partial matching, and the experiments on seven benchmark data sets demonstrate promising results of the BRDs for image classification.

  8. Potential fitting biases resulting from grouping data into variable width bins

    International Nuclear Information System (INIS)

    Towers, S.

    2014-01-01

    When reading peer-reviewed scientific literature describing any analysis of empirical data, it is natural and correct to proceed with the underlying assumption that experiments have made good faith efforts to ensure that their analyses yield unbiased results. However, particle physics experiments are expensive and time consuming to carry out, thus if an analysis has inherent bias (even if unintentional), much money and effort can be wasted trying to replicate or understand the results, particularly if the analysis is fundamental to our understanding of the universe. In this note we discuss the significant biases that can result from data binning schemes. As we will show, if data are binned such that they provide the best comparison to a particular (but incorrect) model, the resulting model parameter estimates when fitting to the binned data can be significantly biased, leading us to too often accept the model hypothesis when it is not in fact true. When using binned likelihood or least squares methods there is of course no a priori requirement that data bin sizes need to be constant, but we show that fitting to data grouped into variable width bins is particularly prone to produce biased results if the bin boundaries are chosen to optimize the comparison of the binned data to a wrong model. The degree of bias that can be achieved simply with variable binning can be surprisingly large. Fitting the data with an unbinned likelihood method, when possible to do so, is the best way for researchers to show that their analyses are not biased by binning effects. Failing that, equal bin widths should be employed as a cross-check of the fitting analysis whenever possible

  9. Potential fitting biases resulting from grouping data into variable width bins

    Energy Technology Data Exchange (ETDEWEB)

    Towers, S., E-mail: smtowers@asu.edu

    2014-07-30

    When reading peer-reviewed scientific literature describing any analysis of empirical data, it is natural and correct to proceed with the underlying assumption that experiments have made good faith efforts to ensure that their analyses yield unbiased results. However, particle physics experiments are expensive and time consuming to carry out, thus if an analysis has inherent bias (even if unintentional), much money and effort can be wasted trying to replicate or understand the results, particularly if the analysis is fundamental to our understanding of the universe. In this note we discuss the significant biases that can result from data binning schemes. As we will show, if data are binned such that they provide the best comparison to a particular (but incorrect) model, the resulting model parameter estimates when fitting to the binned data can be significantly biased, leading us to too often accept the model hypothesis when it is not in fact true. When using binned likelihood or least squares methods there is of course no a priori requirement that data bin sizes need to be constant, but we show that fitting to data grouped into variable width bins is particularly prone to produce biased results if the bin boundaries are chosen to optimize the comparison of the binned data to a wrong model. The degree of bias that can be achieved simply with variable binning can be surprisingly large. Fitting the data with an unbinned likelihood method, when possible to do so, is the best way for researchers to show that their analyses are not biased by binning effects. Failing that, equal bin widths should be employed as a cross-check of the fitting analysis whenever possible.

  10. Waste Isolation Pilot Plant Dry Bin-Scale Integrated Systems Checkout Plan

    International Nuclear Information System (INIS)

    1991-04-01

    In order to determine the long-term performance of the Waste Isolation Pilot Plant (WIPP) disposal system, in accordance with the requirements of the US Environmental Protection Agency (EPA) Standard 40 CFR 191, Subpart B, Sections 13 and 15, two performance assessment tests will be conducted. The tests are titled WIPP Bin-Scale Contact Handled (CH) Transuranic (TRU) Waste Tests and WIPP In Situ Alcove CH TRU Waste Tests. These tests are designed to measure the gas generation characteristics of CH TRU waste. Much of the waste will be specially prepared to provide data for a better understanding of the interactions due to differing degradation modes, waste forms, and repository environmental affects. The bin-scale test is designed to emplace nominally 146 bins. The majority of the bins will contain various forms of waste. Eight bins will be used as reference bins and will contain no waste. This checkout plan exercises the systems, operating procedures, and training readiness of personnel to safely carry out those specifically dedicated activities associated with conducting the bin-scale test plan for dry bins only. The plan does not address the entire WIPP facility readiness state. 18 refs., 6 figs., 3 tabs

  11. Brassinosteroids regulate pavement cell growth by mediating BIN2-induced microtubule stabilization.

    Science.gov (United States)

    Liu, Xiaolei; Yang, Qin; Wang, Yuan; Wang, Linhai; Fu, Ying; Wang, Xuelu

    2018-02-23

    Brassinosteroids (BRs), a group of plant steroid hormones, play important roles in regulating plant development. The cytoskeleton also affects key developmental processes and a deficiency in BR biosynthesis or signaling leads to abnormal phenotypes similar to those of microtubule-defective mutants. However, how BRs regulate microtubule and cell morphology remains unknown. Here, using liquid chromatography-tandem mass spectrometry, we identified tubulin proteins that interact with Arabidopsis BRASSINOSTEROID INSENSITIVE2 (BIN2), a negative regulator of BR responses in plants. In vitro and in vivo pull-down assays confirmed that BIN2 interacts with tubulin proteins. High-speed co-sedimentation assays demonstrated that BIN2 also binds microtubules. The Arabidopsis genome also encodes two BIN2 homologs, BIN2-LIKE 1 (BIL1) and BIL2, which function redundantly with BIN2. In the bin2-3 bil1 bil2 triple mutant, cortical microtubules were more sensitive to treatment with the microtubule-disrupting drug oryzalin than in wild-type, whereas in the BIN2 gain-of-function mutant bin2-1, cortical microtubules were insensitive to oryzalin treatment. These results provide important insight into how BR regulates plant pavement cell and leaf growth by mediating the stabilization of microtubules by BIN2.

  12. The grumpy bin : reducing food waste through playful social interactions

    NARCIS (Netherlands)

    Altarriba, F.; Funk, M.; Lanzani, S.E.; Torralba, A.

    2017-01-01

    Domestic food waste is a world-wide problem that is complex and difficult to tackle as it touches diverse habits and social behaviors. This paper introduces the Grumpy Bin, a smart food waste bin designed for the context of student housing. The Grumpy Bin1 contributes to the state of the art of food

  13. Pakistan andis Osama bin Ladeni jahtimisel alla / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2004-01-01

    Pakistani president Pervez Musharrafi sõnul on Osama bin Ladeni otsingud Lõuna-Waziristanis tulemusteta. Edaspidi keskendutakse otsingutel Põhja-Waziristani, oletatakse, et bin Laden võib olla ka Tora Bora koobastikus. Lisa: USA hambutu luureteenistus

  14. An experimental comparison of some heuristics for cardinality constrained bin packing problem

    Directory of Open Access Journals (Sweden)

    Maja Remic

    2012-01-01

    Full Text Available Background: Bin packing is an NPhard optimization problem of packing items of given sizes into minimum number of capacitylimited bins. Besides the basic problem, numerous other variants of bin packing exist. The cardinality constrained bin packing adds an additional constraint that the number of items in a bin must not exceed a given limit Nmax. Objectives: Goal of the paper is to present a preliminary experimental study which demostrates adaptations of the new algorithms to the general cardinality constrained bin packing problem. Methods/Approach: Straightforward modifications of First Fit Decreasing (FFD, Refined First Fit (RFF and the algorithm by Zhang et al. for the bin packing problem are compared to four cardinality constrained bin packing problem specific algorithms on random lists of items with 0%, 10%, 30% and 50% of large items. The behaviour of all algorithms when cardinality constraint Nmax increases is also studied. Results: Results show that all specific algorithms outperform the general algorithms on lists with low percentage of big items. Conclusions: One of the specific algorithms performs better or equally well even on lists with high percentage of big items and is therefore of significant interest. The behaviour when Nmax increases shows that specific algorithms can be used for solving the general bin packing problem as well.

  15. Pylogeny: an open-source Python framework for phylogenetic tree reconstruction and search space heuristics

    Directory of Open Access Journals (Sweden)

    Alexander Safatli

    2015-06-01

    Full Text Available Summary. Pylogeny is a cross-platform library for the Python programming language that provides an object-oriented application programming interface for phylogenetic heuristic searches. Its primary function is to permit both heuristic search and analysis of the phylogenetic tree search space, as well as to enable the design of novel algorithms to search this space. To this end, the framework supports the structural manipulation of phylogenetic trees, in particular using rearrangement operators such as NNI, SPR, and TBR, the scoring of trees using parsimony and likelihood methods, the construction of a tree search space graph, and the programmatic execution of a few existing heuristic programs. The library supports a range of common phylogenetic file formats and can be used for both nucleotide and protein data. Furthermore, it is also capable of supporting GPU likelihood calculation on nucleotide character data through the BEAGLE library.Availability. Existing development and source code is available for contribution and for download by the public from GitHub (http://github.com/AlexSafatli/Pylogeny. A stable release of this framework is available for download through PyPi (Python Package Index at http://pypi.python.org/pypi/pylogeny.

  16. Multi-dimensional Bin Packing Problems with Guillotine Constraints

    DEFF Research Database (Denmark)

    Amossen, Rasmus Resen; Pisinger, David

    2010-01-01

    The problem addressed in this paper is the decision problem of determining if a set of multi-dimensional rectangular boxes can be orthogonally packed into a rectangular bin while satisfying the requirement that the packing should be guillotine cuttable. That is, there should exist a series of face...... parallel straight cuts that can recursively cut the bin into pieces so that each piece contains a box and no box has been intersected by a cut. The unrestricted problem is known to be NP-hard. In this paper we present a generalization of a constructive algorithm for the multi-dimensional bin packing...... problem, with and without the guillotine constraint, based on constraint programming....

  17. 30 CFR 56.16002 - Bins, hoppers, silos, tanks, and surge piles.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bins, hoppers, silos, tanks, and surge piles... MINES Materials Storage and Handling § 56.16002 Bins, hoppers, silos, tanks, and surge piles. (a) Bins, hoppers, silos, tanks, and surge piles, where loose unconsolidated materials are stored, handled or...

  18. 30 CFR 57.16002 - Bins, hoppers, silos, tanks, and surge piles.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Bins, hoppers, silos, tanks, and surge piles... NONMETAL MINES Materials Storage and Handling § 57.16002 Bins, hoppers, silos, tanks, and surge piles. (a) Bins, hoppers, silos, tanks, and surge piles, where loose unconsolidated materials are stored, handled...

  19. The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles.

    Directory of Open Access Journals (Sweden)

    Bing Xu

    2017-08-01

    Full Text Available Microparticles (MPs are cell-cell communication vesicles derived from the cell surface plasma membrane, although they are not known to originate from cardiac ventricular muscle. In ventricular cardiomyocytes, the membrane deformation protein cardiac bridging integrator 1 (cBIN1 or BIN1+13+17 creates transverse-tubule (t-tubule membrane microfolds, which facilitate ion channel trafficking and modulate local ionic concentrations. The microfold-generated microdomains continuously reorganize, adapting in response to stress to modulate the calcium signaling apparatus. We explored the possibility that cBIN1-microfolds are externally released from cardiomyocytes. Using electron microscopy imaging with immunogold labeling, we found in mouse plasma that cBIN1 exists in membrane vesicles about 200 nm in size, which is consistent with the size of MPs. In mice with cardiac-specific heterozygous Bin1 deletion, flow cytometry identified 47% less cBIN1-MPs in plasma, supporting cardiac origin. Cardiac release was also evidenced by the detection of cBIN1-MPs in medium bathing a pure population of isolated adult mouse cardiomyocytes. In human plasma, osmotic shock increased cBIN1 detection by enzyme-linked immunosorbent assay (ELISA, and cBIN1 level decreased in humans with heart failure, a condition with reduced cardiac muscle cBIN1, both of which support cBIN1 release in MPs from human hearts. Exploring putative mechanisms of MP release, we found that the membrane fission complex endosomal sorting complexes required for transport (ESCRT-III subunit charged multivesicular body protein 4B (CHMP4B colocalizes and coimmunoprecipitates with cBIN1, an interaction enhanced by actin stabilization. In HeLa cells with cBIN1 overexpression, knockdown of CHMP4B reduced the release of cBIN1-MPs. Using truncation mutants, we identified that the N-terminal BAR (N-BAR domain in cBIN1 is required for CHMP4B binding and MP release. This study links the BAR protein superfamily

  20. The ESCRT-III pathway facilitates cardiomyocyte release of cBIN1-containing microparticles.

    Science.gov (United States)

    Xu, Bing; Fu, Ying; Liu, Yan; Agvanian, Sosse; Wirka, Robert C; Baum, Rachel; Zhou, Kang; Shaw, Robin M; Hong, TingTing

    2017-08-01

    Microparticles (MPs) are cell-cell communication vesicles derived from the cell surface plasma membrane, although they are not known to originate from cardiac ventricular muscle. In ventricular cardiomyocytes, the membrane deformation protein cardiac bridging integrator 1 (cBIN1 or BIN1+13+17) creates transverse-tubule (t-tubule) membrane microfolds, which facilitate ion channel trafficking and modulate local ionic concentrations. The microfold-generated microdomains continuously reorganize, adapting in response to stress to modulate the calcium signaling apparatus. We explored the possibility that cBIN1-microfolds are externally released from cardiomyocytes. Using electron microscopy imaging with immunogold labeling, we found in mouse plasma that cBIN1 exists in membrane vesicles about 200 nm in size, which is consistent with the size of MPs. In mice with cardiac-specific heterozygous Bin1 deletion, flow cytometry identified 47% less cBIN1-MPs in plasma, supporting cardiac origin. Cardiac release was also evidenced by the detection of cBIN1-MPs in medium bathing a pure population of isolated adult mouse cardiomyocytes. In human plasma, osmotic shock increased cBIN1 detection by enzyme-linked immunosorbent assay (ELISA), and cBIN1 level decreased in humans with heart failure, a condition with reduced cardiac muscle cBIN1, both of which support cBIN1 release in MPs from human hearts. Exploring putative mechanisms of MP release, we found that the membrane fission complex endosomal sorting complexes required for transport (ESCRT)-III subunit charged multivesicular body protein 4B (CHMP4B) colocalizes and coimmunoprecipitates with cBIN1, an interaction enhanced by actin stabilization. In HeLa cells with cBIN1 overexpression, knockdown of CHMP4B reduced the release of cBIN1-MPs. Using truncation mutants, we identified that the N-terminal BAR (N-BAR) domain in cBIN1 is required for CHMP4B binding and MP release. This study links the BAR protein superfamily to the ESCRT

  1. Miks Osama bin Ladenit pole siiani tabatud? / Peeter Ernits

    Index Scriptorium Estoniae

    Ernits, Peeter, 1953-

    2008-01-01

    Afganistanis viibinud ajakirjaniku eesmärgiks oli teada saada, miks vaatamata kõigile püüdlustele vägivald Afganistanis siiski ei vähene ning kus varjab ennast Al Qaeda liider Osama bin Laden. Lisad: Osama bin Laden; 11. september 2001

  2. BinMag: Widget for comparing stellar observed with theoretical spectra

    Science.gov (United States)

    Kochukhov, O.

    2018-05-01

    BinMag examines theoretical stellar spectra computed with Synth/SynthMag/Synmast/Synth3/SME spectrum synthesis codes and compare them to observations. An IDL widget program, BinMag applies radial velocity shift and broadening to the theoretical spectra to account for the effects of stellar rotation, radial-tangential macroturbulence, instrumental smearing. The code can also simulate spectra of spectroscopic binary stars by appropriate coaddition of two synthetic spectra. Additionally, BinMag can be used to measure equivalent width, fit line profile shapes with analytical functions, and to automatically determine radial velocity and broadening parameters. BinMag interfaces with the Synth3 (ascl:1212.010) and SME (ascl:1202.013) codes, allowing the user to determine chemical abundances and stellar atmospheric parameters from the observed spectra.

  3. Vicarious revenge and the death of Osama bin Laden.

    Science.gov (United States)

    Gollwitzer, Mario; Skitka, Linda J; Wisneski, Daniel; Sjöström, Arne; Liberman, Peter; Nazir, Syed Javed; Bushman, Brad J

    2014-05-01

    Three hypotheses were derived from research on vicarious revenge and tested in the context of the assassination of Osama bin Laden in 2011. In line with the notion that revenge aims at delivering a message (the "message hypothesis"), Study 1 shows that Americans' vengeful desires in the aftermath of 9/11 predicted a sense of justice achieved after bin Laden's death, and that this effect was mediated by perceptions that his assassination sent a message to the perpetrators to not "mess" with the United States. In line with the "blood lust hypothesis," his assassination also sparked a desire to take further revenge and to continue the "war on terror." Finally, in line with the "intent hypothesis," Study 2 shows that Americans (but not Pakistanis or Germans) considered the fact that bin Laden was killed intentionally more satisfactory than the possibility of bin Laden being killed accidentally (e.g., in an airplane crash).

  4. Harmony Search Based Parameter Ensemble Adaptation for Differential Evolution

    Directory of Open Access Journals (Sweden)

    Rammohan Mallipeddi

    2013-01-01

    Full Text Available In differential evolution (DE algorithm, depending on the characteristics of the problem at hand and the available computational resources, different strategies combined with a different set of parameters may be effective. In addition, a single, well-tuned combination of strategies and parameters may not guarantee optimal performance because different strategies combined with different parameter settings can be appropriate during different stages of the evolution. Therefore, various adaptive/self-adaptive techniques have been proposed to adapt the DE strategies and parameters during the course of evolution. In this paper, we propose a new parameter adaptation technique for DE based on ensemble approach and harmony search algorithm (HS. In the proposed method, an ensemble of parameters is randomly sampled which form the initial harmony memory. The parameter ensemble evolves during the course of the optimization process by HS algorithm. Each parameter combination in the harmony memory is evaluated by testing them on the DE population. The performance of the proposed adaptation method is evaluated using two recently proposed strategies (DE/current-to-pbest/bin and DE/current-to-gr_best/bin as basic DE frameworks. Numerical results demonstrate the effectiveness of the proposed adaptation technique compared to the state-of-the-art DE based algorithms on a set of challenging test problems (CEC 2005.

  5. MetaBAT: Metagenome Binning based on Abundance and Tetranucleotide frequence

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Dongwan; Froula, Jeff; Egan, Rob; Wang, Zhong

    2014-03-21

    Grouping large fragments assembled from shotgun metagenomic sequences to deconvolute complex microbial communities, or metagenome binning, enables the study of individual organisms and their interactions. Here we developed automated metagenome binning software, called MetaBAT, which integrates empirical probabilistic distances of genome abundance and tetranucleotide frequency. On synthetic datasets MetaBAT on average achieves 98percent precision and 90percent recall at the strain level with 281 near complete unique genomes. Applying MetaBAT to a human gut microbiome data set we recovered 176 genome bins with 92percent precision and 80percent recall. Further analyses suggest MetaBAT is able to recover genome fragments missed in reference genomes up to 19percent, while 53 genome bins are novel. In summary, we believe MetaBAT is a powerful tool to facilitate comprehensive understanding of complex microbial communities.

  6. Strong Production SUSY Searches at ATLAS and CMS

    CERN Document Server

    Marshall, Z L

    2015-01-01

    The results of searches for strongly-produced supersymmetry at the Large Hadron Collider by the ATLAS and CMS collaborations are presented. Several of the historically strongest zero-and one-lepton final state searches have been updated to include multi-bin fits and combinations. In addition, new two-lepton final state search results are shown from CMS and ATLAS, which show 2.6 and 3.0 standard deviation excesses, respectively, above the standard model expectation, albeit in different regions of phase space. Both collaborations have also shown new searches that cover areas uncovered by previous searches, in both searches for light stops and searches for stealth supersymmetry.

  7. OERScout Technology Framework: A Novel Approach to Open Educational Resources Search

    Directory of Open Access Journals (Sweden)

    Ishan Sudeera Abeywardena

    2013-09-01

    Full Text Available The open educational resources (OER movement has gained momentum in the past few years. With this new drive towards making knowledge open and accessible, a large number of OER repositories have been established and made available online throughout the world. However, the inability of existing search engines such as Google, Yahoo!, and Bing to effectively search for useful OER which are of acceptable academic standard for teaching purposes is a major factor contributing to the slow uptake of the entire movement. As a major step towards solving this issue, this paper proposes OERScout, a technology framework based on text mining solutions. The objectives of our work are to (i develop a technology framework which will parametrically measure the usefulness of an OER for a particular academic purpose based on the openness, accessibility, and relevance attributes; and (ii provide academics with a mechanism to locate OER which are of an acceptable academic standard. From our user tests, we have identified that OERScout is a sound solution for effectively zeroing in on OER which can be readily used for teaching and learning purposes.

  8. Quantitative image quality evaluation of pixel-binning in a flat-panel detector for x-ray fluoroscopy

    International Nuclear Information System (INIS)

    Srinivas, Yogesh; Wilson, David L.

    2004-01-01

    X-ray fluoroscopy places stringent design requirements on new flat-panel (FP) detectors, requiring both low-noise electronics and high data transfer rates. Pixel-binning, wherein data from more that one detector pixel are collected simultaneously, not only lowers the data transfer rate but also increases x-ray counts and pixel signal-to-noise ratio (SNR). In this study, we quantitatively assessed image quality of image sequences from four acquisition methods; no-binning and three types of binning; in synthetic images using a clinically relevant task of detecting an extended guidewire in a four-alternative forced-choice paradigm. Binning methods were conventional data-line (D) and gate-line (G) binning, and a novel method in which alternate frames in an image sequence used D and G binning. Two detector orientations placed the data lines either parallel or perpendicular to the guide wire. At a low exposure of 0.6 μR (1.548x10 -10 C/kg) per frame, irrespective of detector orientation, D binning with its reduced electronic noise was significantly (p -10 C/kg) per frame, with data lines parallel to the guidewire, detection with D binning was significantly (p<0.1) better than G binning. However, with data lines perpendicular to the guidewire, G binning was significantly (p<0.1) better than D binning because the partial area effect was reduced. Alternate binning was the best binning method when results were averaged over both orientations, and it was as good as the best binning method at either orientation. In addition, at low and high exposures, alternate binning gave a temporally fused image with a smooth guidewire, an important image quality feature not assessed in a detection experiment. While at high exposure, detection with no binning was as good, or better, than the best binning method, it might be impractical at fluoroscopy imaging rates. A computational observer model based on signal detection theory successfully fit data and was used to predict effects of

  9. Solid waste bin detection and classification using Dynamic Time Warping and MLP classifier

    Energy Technology Data Exchange (ETDEWEB)

    Islam, Md. Shafiqul, E-mail: shafique@eng.ukm.my [Dept. of Electrical, Electronic and Systems Engineering, Universiti Kebangsaan Malaysia, Bangi 43600, Selangore (Malaysia); Hannan, M.A., E-mail: hannan@eng.ukm.my [Dept. of Electrical, Electronic and Systems Engineering, Universiti Kebangsaan Malaysia, Bangi 43600, Selangore (Malaysia); Basri, Hassan [Dept. of Civil and Structural Engineering, Universiti Kebangsaan Malaysia, Bangi 43600, Selangore (Malaysia); Hussain, Aini; Arebey, Maher [Dept. of Electrical, Electronic and Systems Engineering, Universiti Kebangsaan Malaysia, Bangi 43600, Selangore (Malaysia)

    2014-02-15

    Highlights: • Solid waste bin level detection using Dynamic Time Warping (DTW). • Gabor wavelet filter is used to extract the solid waste image features. • Multi-Layer Perceptron classifier network is used for bin image classification. • The classification performance evaluated by ROC curve analysis. - Abstract: The increasing requirement for Solid Waste Management (SWM) has become a significant challenge for municipal authorities. A number of integrated systems and methods have introduced to overcome this challenge. Many researchers have aimed to develop an ideal SWM system, including approaches involving software-based routing, Geographic Information Systems (GIS), Radio-frequency Identification (RFID), or sensor intelligent bins. Image processing solutions for the Solid Waste (SW) collection have also been developed; however, during capturing the bin image, it is challenging to position the camera for getting a bin area centralized image. As yet, there is no ideal system which can correctly estimate the amount of SW. This paper briefly discusses an efficient image processing solution to overcome these problems. Dynamic Time Warping (DTW) was used for detecting and cropping the bin area and Gabor wavelet (GW) was introduced for feature extraction of the waste bin image. Image features were used to train the classifier. A Multi-Layer Perceptron (MLP) classifier was used to classify the waste bin level and estimate the amount of waste inside the bin. The area under the Receiver Operating Characteristic (ROC) curves was used to statistically evaluate classifier performance. The results of this developed system are comparable to previous image processing based system. The system demonstration using DTW with GW for feature extraction and an MLP classifier led to promising results with respect to the accuracy of waste level estimation (98.50%). The application can be used to optimize the routing of waste collection based on the estimated bin level.

  10. Surface contamination of hazardous drug pharmacy storage bins and pharmacy distributor shipping containers.

    Science.gov (United States)

    Redic, Kimberly A; Fang, Kayleen; Christen, Catherine; Chaffee, Bruce W

    2018-03-01

    Purpose This study was conducted to determine whether there is contamination on exterior drug packaging using shipping totes from the distributor and carousel storage bins as surrogate markers of external packaging contamination. Methods A two-part study was conducted to measure the presence of 5-fluorouracil, ifosfamide, cyclophosphamide, docetaxel and paclitaxel using surrogate markers for external drug packaging. In Part I, 10 drug distributor shipping totes designated for transport of hazardous drugs provided a snapshot view of contamination from regular use and transit in and out of the pharmacy. An additional two totes designated for transport of non-hazardous drugs served as controls. In Part II, old carousel storage bins (i.e. those in use pre-study) were wiped for snapshot view of hazardous drug contamination on storage bins. New carousel storage bins were then put into use for storage of the five tested drugs and used for routine storage and inventory maintenance activities. Carousel bins were wiped at time intervals 0, 8, 16 and 52 weeks to measure surface contamination. Results Two of the 10 hazardous shipping totes were contaminated. Three of the five-old carousel bins were contaminated with cyclophosphamide. One of the old carousel bins was also contaminated with ifosfamide. There were no detectable levels of hazardous drugs on any of the new storage bins at time 0, 8 or 16 weeks. However, at the Week 52, there was a detectable level of 5-FU present in the 5-FU carousel bin. Conclusions Contamination of the surrogate markers suggests that external packaging for hazardous drugs is contaminated, either during the manufacturing process or during routine chain of custody activities. These results demonstrate that occupational exposure may occur due to contamination from shipping totes and storage bins, and that handling practices including use of personal protective equipment is warranted.

  11. Osama bin Laden võib olla uues piiramisrõngas / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2004-01-01

    Briti ajakirjanduse andmeil on suudetud tuvastada bin Ladeni asukoht. 1993. aastal CIA peakorteri ees kaks USA luureagenti tapnud pakistanlase Mir Aimal Kasi ja bin Ladeni tagaotsimisest. Vt. samas: Taliban kogub uut jõudu

  12. A swarm intelligence framework for reconstructing gene networks: searching for biologically plausible architectures.

    Science.gov (United States)

    Kentzoglanakis, Kyriakos; Poole, Matthew

    2012-01-01

    In this paper, we investigate the problem of reverse engineering the topology of gene regulatory networks from temporal gene expression data. We adopt a computational intelligence approach comprising swarm intelligence techniques, namely particle swarm optimization (PSO) and ant colony optimization (ACO). In addition, the recurrent neural network (RNN) formalism is employed for modeling the dynamical behavior of gene regulatory systems. More specifically, ACO is used for searching the discrete space of network architectures and PSO for searching the corresponding continuous space of RNN model parameters. We propose a novel solution construction process in the context of ACO for generating biologically plausible candidate architectures. The objective is to concentrate the search effort into areas of the structure space that contain architectures which are feasible in terms of their topological resemblance to real-world networks. The proposed framework is initially applied to the reconstruction of a small artificial network that has previously been studied in the context of gene network reverse engineering. Subsequently, we consider an artificial data set with added noise for reconstructing a subnetwork of the genetic interaction network of S. cerevisiae (yeast). Finally, the framework is applied to a real-world data set for reverse engineering the SOS response system of the bacterium Escherichia coli. Results demonstrate the relative advantage of utilizing problem-specific knowledge regarding biologically plausible structural properties of gene networks over conducting a problem-agnostic search in the vast space of network architectures.

  13. Binning sequences using very sparse labels within a metagenome

    Directory of Open Access Journals (Sweden)

    Halgamuge Saman K

    2008-04-01

    Full Text Available Abstract Background In metagenomic studies, a process called binning is necessary to assign contigs that belong to multiple species to their respective phylogenetic groups. Most of the current methods of binning, such as BLAST, k-mer and PhyloPythia, involve assigning sequence fragments by comparing sequence similarity or sequence composition with already-sequenced genomes that are still far from comprehensive. We propose a semi-supervised seeding method for binning that does not depend on knowledge of completed genomes. Instead, it extracts the flanking sequences of highly conserved 16S rRNA from the metagenome and uses them as seeds (labels to assign other reads based on their compositional similarity. Results The proposed seeding method is implemented on an unsupervised Growing Self-Organising Map (GSOM, and called Seeded GSOM (S-GSOM. We compared it with four well-known semi-supervised learning methods in a preliminary test, separating random-length prokaryotic sequence fragments sampled from the NCBI genome database. We identified the flanking sequences of the highly conserved 16S rRNA as suitable seeds that could be used to group the sequence fragments according to their species. S-GSOM showed superior performance compared to the semi-supervised methods tested. Additionally, S-GSOM may also be used to visually identify some species that do not have seeds. The proposed method was then applied to simulated metagenomic datasets using two different confidence threshold settings and compared with PhyloPythia, k-mer and BLAST. At the reference taxonomic level Order, S-GSOM outperformed all k-mer and BLAST results and showed comparable results with PhyloPythia for each of the corresponding confidence settings, where S-GSOM performed better than PhyloPythia in the ≥ 10 reads datasets and comparable in the ≥ 8 kb benchmark tests. Conclusion In the task of binning using semi-supervised learning methods, results indicate S-GSOM to be the best of

  14. Increasing Donations to Supermarket Food-Bank Bins Using Proximal Prompts

    OpenAIRE

    Farrimond, Samantha J; Leland, Louis S

    2006-01-01

    There has been little research into interventions to increase participation in donating items to food-bank bins. In New Zealand, there has been an increased demand from food banks (Stewart, 2002). This study demonstrated that point-of-sale prompts can be an effective method of increasing donations to a supermarket food-bank bin.

  15. Lanthanide metal-organic frameworks

    International Nuclear Information System (INIS)

    Cheng, Peng

    2015-01-01

    This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

  16. Lanthanide metal-organic frameworks

    Energy Technology Data Exchange (ETDEWEB)

    Cheng, Peng (ed.) [Nankai Univ., Tianjin (China). Dept. of Chemistry

    2015-03-01

    This book contains the following nine chapters: lanthanide metal-organic frameworks: syntheses, properties, and potential applications (Stephen Fordham, Xuan Wang, Mathieu Bosch, Hong-Cai Zhou); 2. chiral lanthanide metal-organic frameworks (Weisheng Liu, Xiaoliang Tang); 3. Porous lanthanide metal-organic frameworks for gas storage and separation (Bin Li, Banglin Chen); 4. Luminescent lanthanide metal-organic frameworks (Xue-Zhi Song, Shu-Yan Song, Hong-Jie Zhang); 5. Metal-organic frameworks based on lanthanide clusters (Lian Chen, Feilong Jiang, Kang Zhou, Mingyan Wu, Maochun Hong); 6. metal-organic frameworks with d-f cyanide bridges: structural diversity, bonding regime, and magnetism (Marilena Ferbinteanu, Fanica Cimpoesu, Stefania Tanase); 7. transition-lanthanide heterometal-organic frameworks: synthesis, structures, and properties (Wei Shi, Ke Liu, Peng Cheng); 8: MOFs of uranium and the actinides (Juan Su, Jiesheng Chen); 9. Nanostructured and/or nanoscale lanthanide metal-organic frameworks (Zhonghao Zhang, Zhiping Zheng).

  17. Bin-packing problems with load balancing and stability constraints

    DEFF Research Database (Denmark)

    Trivella, Alessio; Pisinger, David

    apper in a wide range of disciplines, including transportation and logistics, computer science, engineering, economics and manufacturing. The problem is well-known to be N P-hard and difficult to solve in practice, especially when dealing with the multi-dimensional cases. Closely connected to the BPP...... realistic constraints related to e.g. load balancing, cargo stability and weight limits, in the multi-dimensional BPP. The BPP poses additional challenges compared to the CLP due to the supplementary objective of minimizing the number of bins. In particular, in section 2 we discuss how to integrate bin......-packing and load balancing of items. The problem has only been considered in the literature in simplified versions, e.g. balancing a single bin or introducing a feasible region for the barycenter. In section 3 we generalize the problem to handle cargo stability and weight constraints....

  18. Increasing Donations to Supermarket Food-Bank Bins Using Proximal Prompts

    Science.gov (United States)

    Farrimond, Samantha J.; Leland, Louis S., Jr.

    2006-01-01

    There has been little research into interventions to increase participation in donating items to food-bank bins. In New Zealand, there has been an increased demand from food banks (Stewart, 2002). This study demonstrated that point-of-sale prompts can be an effective method of increasing donations to a supermarket food-bank bin. (Contains 1…

  19. Efficient visibility-driven medical image visualisation via adaptive binned visibility histogram.

    Science.gov (United States)

    Jung, Younhyun; Kim, Jinman; Kumar, Ashnil; Feng, David Dagan; Fulham, Michael

    2016-07-01

    'Visibility' is a fundamental optical property that represents the observable, by users, proportion of the voxels in a volume during interactive volume rendering. The manipulation of this 'visibility' improves the volume rendering processes; for instance by ensuring the visibility of regions of interest (ROIs) or by guiding the identification of an optimal rendering view-point. The construction of visibility histograms (VHs), which represent the distribution of all the visibility of all voxels in the rendered volume, enables users to explore the volume with real-time feedback about occlusion patterns among spatially related structures during volume rendering manipulations. Volume rendered medical images have been a primary beneficiary of VH given the need to ensure that specific ROIs are visible relative to the surrounding structures, e.g. the visualisation of tumours that may otherwise be occluded by neighbouring structures. VH construction and its subsequent manipulations, however, are computationally expensive due to the histogram binning of the visibilities. This limits the real-time application of VH to medical images that have large intensity ranges and volume dimensions and require a large number of histogram bins. In this study, we introduce an efficient adaptive binned visibility histogram (AB-VH) in which a smaller number of histogram bins are used to represent the visibility distribution of the full VH. We adaptively bin medical images by using a cluster analysis algorithm that groups the voxels according to their intensity similarities into a smaller subset of bins while preserving the distribution of the intensity range of the original images. We increase efficiency by exploiting the parallel computation and multiple render targets (MRT) extension of the modern graphical processing units (GPUs) and this enables efficient computation of the histogram. We show the application of our method to single-modality computed tomography (CT), magnetic resonance

  20. Hydra: a scalable proteomic search engine which utilizes the Hadoop distributed computing framework.

    Science.gov (United States)

    Lewis, Steven; Csordas, Attila; Killcoyne, Sarah; Hermjakob, Henning; Hoopmann, Michael R; Moritz, Robert L; Deutsch, Eric W; Boyle, John

    2012-12-05

    For shotgun mass spectrometry based proteomics the most computationally expensive step is in matching the spectra against an increasingly large database of sequences and their post-translational modifications with known masses. Each mass spectrometer can generate data at an astonishingly high rate, and the scope of what is searched for is continually increasing. Therefore solutions for improving our ability to perform these searches are needed. We present a sequence database search engine that is specifically designed to run efficiently on the Hadoop MapReduce distributed computing framework. The search engine implements the K-score algorithm, generating comparable output for the same input files as the original implementation. The scalability of the system is shown, and the architecture required for the development of such distributed processing is discussed. The software is scalable in its ability to handle a large peptide database, numerous modifications and large numbers of spectra. Performance scales with the number of processors in the cluster, allowing throughput to expand with the available resources.

  1. Tensor network states in time-bin quantum optics

    Science.gov (United States)

    Lubasch, Michael; Valido, Antonio A.; Renema, Jelmer J.; Kolthammer, W. Steven; Jaksch, Dieter; Kim, M. S.; Walmsley, Ian; García-Patrón, Raúl

    2018-06-01

    The current shift in the quantum optics community towards experiments with many modes and photons necessitates new classical simulation techniques that efficiently encode many-body quantum correlations and go beyond the usual phase-space formulation. To address this pressing demand we formulate linear quantum optics in the language of tensor network states. We extensively analyze the quantum and classical correlations of time-bin interference in a single fiber loop. We then generalize our results to more complex time-bin quantum setups and identify different classes of architectures for high-complexity and low-overhead boson sampling experiments.

  2. Model-independent search for $CP$ violation in $D^{0} \\to K^{-}K^{+}\\pi^{-}\\pi^{+}$ and $D^{0} \\to \\pi^{-}\\pi^{+}\\pi^{+}\\pi^{-}$ decays

    CERN Document Server

    Aaij, R; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves Jr, A A; Amato, S; Amerio, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Baesso, C; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Bauer, Th; Bay, A; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M -O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Burducea, I; Bursche, A; Busetto, G; Buytaert, J; Cadeddu, S; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casse, G; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cenci, R; Charles, M; Charpentier, Ph; Chen, P; Chiapolini, N; Chrzaszcz, M; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Couturier, B; Cowan, G A; Cowie, E; Craik, D C; Cunliffe, S; Currie, R; D'Ambrosio, C; David, P; David, P N Y; Davis, A; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Dijkstra, H; Dogaru, M; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Falabella, A; Färber, C; Fardell, G; Farinelli, C; Farry, S; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furcas, S; Furfaro, E; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garosi, P; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gorbounov, P; Gordon, H; Gotti, C; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hartmann, T; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Hess, M; Hicheur, A; Hicks, E; Hill, D; Hoballah, M; Hombach, C; Hopchev, P; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jans, E; Jaton, P; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Kaballo, M; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Kenyon, I R; Ketel, T; Keune, A; Khanji, B; Kochebina, O; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudryavtsev, V; Kurek, K; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J -P; Lefèvre, R; Leflat, A; Lefrançois, J; Leo, S; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Li Gioi, L; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; Lohn, S; Longstaff, I; Lopes, J H; Lopez-March, N; Lu, H; Lucchesi, D; Luisier, J; Luo, H; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Manca, G; Mancinelli, G; Maratas, J; Marconi, U; Marino, P; Märki, R; Marks, J; Martellotti, G; Martens, A; Martín Sánchez, A; Martinelli, M; Martinez Santos, D; Martins Tostes, D; Martynov, A; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Maurice, E; Mazurov, A; McCarthy, J; McNab, A; McNulty, R; McSkelly, B; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M -N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mordà, A; Morello, M J; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; Neubert, S; Neufeld, N; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Nicol, M; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Orlandea, M; Otalora Goicochea, J M; Owen, P; Oyanguren, A; Pal, B K; Palano, A; Palczewski, T; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Patrick, G N; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pescatore, L; Pesen, E; Petridis, K; Petrolini, A; Phan, A; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Playfer, S; Plo Casasus, M; Polci, F; Polok, G; Poluektov, A; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redford, S; Reid, M M; dos Reis, A C; Ricciardi, S; Richards, A; Rinnert, K; Rives Molina, V; Roa Romero, D A; Robbe, P; Roberts, D A; Rodrigues, E; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Rouvinet, J; Ruf, T; Ruffini, F; Ruiz, H; Ruiz Valls, P; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Sanmartin Sedes, B; Sannino, M; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schaack, P; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M -H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shatalov, P; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, N A; Smith, E; Smith, J; Smith, M; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Straticiuc, M; Straumann, U; Subbiah, V K; Sun, L; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szumlak, T; T'Jampens, S; Teklishyn, M; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tresch, M; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Urner, D; Ustyuzhanin, A; Uwer, U; Vagnoni, V; Valenti, G; Vallier, A; Van Dijk, M; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; Voss, H; Waldi, R; Wallace, C; Wallace, R; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wicht, J; Wiechczynski, J; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wotton, S A; Wright, S; Wu, S; Wyllie, K; Xie, Y; Xing, Z; Yang, Z; Young, R; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L; Zvyagin, A

    2013-11-04

    A search for $CP$ violation in the phase-space structures of $D^{0}$ and $\\bar{D^{0}}$ decays to the final states $K^{-}K^{+}\\pi^{-}\\pi^{+}$ and $\\pi^{-}\\pi^{+}\\pi^{+}\\pi^{-}$ is presented. The search is carried out with a data set corresponding to an integrated luminosity of 1.0 fb$^{−1}$ collected in 2011 by the LHCb experiment in $pp$ collisions at a centre-of-mass energy of 7 TeV. For the $K^{-}K^{+}\\pi^{-}\\pi^{+}$ final state, the four-body phase space is divided into 32 bins, each bin with approximately 1800 decays. The $p$-value under the hypothesis of no $CP$ violation is 9.1 %, and in no bin is a $CP$ asymmetry greater than 6.5 % observed. The phase space of the $\\pi^{-}\\pi^{+}\\pi^{+}\\pi^{-}$ final state is partitioned into 128 bins, each bin with approximately 2500 decays. The p-value under the hypothesis of no $CP$ violation is 41 %, and in no bin is a $CP$ asymmetry greater than 5.5 % observed. All results are consistent with the hypothesis of no $CP$ violation at the current sensitivity.

  3. Max–min Bin Packing Algorithm and its application in nano-particles filling

    International Nuclear Information System (INIS)

    Zhu, Dingju

    2016-01-01

    With regard to existing bin packing algorithms, higher packing efficiency often leads to lower packing speed while higher packing speed leads to lower packing efficiency. Packing speed and packing efficiency of existing bin packing algorithms including NFD, NF, FF, FFD, BF and BFD correlates negatively with each other, thus resulting in the failure of existing bin packing algorithms to satisfy the demand of nano-particles filling for both high speed and high efficiency. The paper provides a new bin packing algorithm, Max–min Bin Packing Algorithm (MM), which realizes both high packing speed and high packing efficiency. MM has the same packing speed as NFD (whose packing speed ranks no. 1 among existing bin packing algorithms); in case that the size repetition rate of objects to be packed is over 5, MM can realize almost the same packing efficiency as BFD (whose packing efficiency ranks No. 1 among existing bin packing algorithms), and in case that the size repetition rate of objects to be packed is over 500, MM can achieve exactly the same packing efficiency as BFD. With respect to application of nano-particles filling, the size repetition rate of nano particles to be packed is usually in thousands or ten thousands, far higher than 5 or 500. Consequently, in application of nano-particles filling, the packing efficiency of MM is exactly equal to that of BFD. Thus the irreconcilable conflict between packing speed and packing efficiency is successfully removed by MM, which leads to MM having better packing effect than any existing bin packing algorithm. In practice, there are few cases when the size repetition of objects to be packed is lower than 5. Therefore the MM is not necessarily limited to nano-particles filling, and can also be widely used in other applications besides nano-particles filling. Especially, MM has significant value in application of nano-particles filling such as nano printing and nano tooth filling.

  4. Meeting the EU recycling targets by introducing a 2-compartment bin to households

    DEFF Research Database (Denmark)

    Jensen, Morten Bang; Scheutz, Charlotte; Møller, Jacob

    A Danish municipality has introduced a 2-compartment bin in the waste collection scheme, this bin should increase recycling of dry household recyclables. An excessive waste sorting campaign was conducted and the efficiency of the bin assessed. The waste sorting campaign yielded a full waste...... targets can be fulfilled, there is still room for improvement (increase source separation), especially for hard plastic and metals....

  5. Fast and accurate taxonomic assignments of metagenomic sequences using MetaBin.

    Directory of Open Access Journals (Sweden)

    Vineet K Sharma

    Full Text Available Taxonomic assignment of sequence reads is a challenging task in metagenomic data analysis, for which the present methods mainly use either composition- or homology-based approaches. Though the homology-based methods are more sensitive and accurate, they suffer primarily due to the time needed to generate the Blast alignments. We developed the MetaBin program and web server for better homology-based taxonomic assignments using an ORF-based approach. By implementing Blat as the faster alignment method in place of Blastx, the analysis time has been reduced by severalfold. It is benchmarked using both simulated and real metagenomic datasets, and can be used for both single and paired-end sequence reads of varying lengths (≥45 bp. To our knowledge, MetaBin is the only available program that can be used for the taxonomic binning of short reads (<100 bp with high accuracy and high sensitivity using a homology-based approach. The MetaBin web server can be used to carry out the taxonomic analysis, by either submitting reads or Blastx output. It provides several options including construction of taxonomic trees, creation of a composition chart, functional analysis using COGs, and comparative analysis of multiple metagenomic datasets. MetaBin web server and a standalone version for high-throughput analysis are available freely at http://metabin.riken.jp/.

  6. Integrated technologies for solid waste bin monitoring system.

    Science.gov (United States)

    Arebey, Maher; Hannan, M A; Basri, Hassan; Begum, R A; Abdullah, Huda

    2011-06-01

    The integration of communication technologies such as radio frequency identification (RFID), global positioning system (GPS), general packet radio system (GPRS), and geographic information system (GIS) with a camera are constructed for solid waste monitoring system. The aim is to improve the way of responding to customer's inquiry and emergency cases and estimate the solid waste amount without any involvement of the truck driver. The proposed system consists of RFID tag mounted on the bin, RFID reader as in truck, GPRS/GSM as web server, and GIS as map server, database server, and control server. The tracking devices mounted in the trucks collect location information in real time via the GPS. This information is transferred continuously through GPRS to a central database. The users are able to view the current location of each truck in the collection stage via a web-based application and thereby manage the fleet. The trucks positions and trash bin information are displayed on a digital map, which is made available by a map server. Thus, the solid waste of the bin and the truck are being monitored using the developed system.

  7. Automatic Grasp Generation and Improvement for Industrial Bin-Picking

    DEFF Research Database (Denmark)

    Kraft, Dirk; Ellekilde, Lars-Peter; Rytz, Jimmy Alison

    2014-01-01

    and achieve comparable results and that our learning approach can improve system performance significantly. Automatic bin-picking is an important industrial process that can lead to significant savings and potentially keep production in countries with high labour cost rather than outsourcing it. The presented......This paper presents work on automatic grasp generation and grasp learning for reducing the manual setup time and increase grasp success rates within bin-picking applications. We propose an approach that is able to generate good grasps automatically using a dynamic grasp simulator, a newly developed...

  8. Grasp Densities for Grasp Refinement in Industrial Bin Picking

    DEFF Research Database (Denmark)

    Hupfauf, Benedikt; Hahn, Heiko; Bodenhagen, Leon

    in terms of object-relative gripper pose, can be learned from empirical experience, and allow the automatic choice of optimal grasps in a given scene context (object pose, workspace constraints, etc.). We will show grasp densities extracted from empirical data in a real industrial bin picking context...... generated in industrial bin-picking for grasp learning. This aim is achieved by using the novel concept of grasp densities (Detry et al., 2010). Grasp densities can describe the full variety of grasps that apply to specific objects using specific grippers. They represent the likelihood of grasp success...

  9. Evaluation Of Plutonium Oxide Destructive Chemical Analyses For Validity Of Original 3013 Container Binning

    International Nuclear Information System (INIS)

    Mcclard, J.; Kessinger, G.

    2010-01-01

    The surveillance program for 3013 containers is based, in part, on the separation of containers into various bins related to potential container failure mechanisms. The containers are assigned to bins based on moisture content and pre-storage estimates of content chemistry. While moisture content is measured during the packaging of each container, chemistry estimates are made by using a combination of process knowledge, packaging data and prompt gamma analyses to establish the moisture and chloride/fluoride content of the materials. Packages with high moisture and chloride/fluoride contents receive more detailed surveillances than packages with less chloride/fluoride and/or moisture. Moisture verification measurements and chemical analyses performed during the surveillance program provided an opportunity to validate the binning process. Validation results demonstrated that the binning effort was generally successful in placing the containers in the appropriate bin for surveillance and analysis.

  10. A compost bin for handling privy wastes: its fabrication and use

    Science.gov (United States)

    R.E. Leonard; S.C. Fay

    1978-01-01

    A 24-ft3 (6.8-m3) fiberglass bin was constructed and tested for its effectiveness in composting privy wastes. A mixture of ground hardwood bark and raw sewage was used for composting. Temperatures in excess of 60°C for 36 hours were produced in the bin by aerobic, thermophilic composting. This temperature is...

  11. Conceptual and mathematical advances in the search for a unified framework

    CERN Document Server

    Müller, Olaf; Nardmann, Marc; Tolksdorf, Jürgen; Zeidler, Eberhard; Quantum field theory and gravity

    2012-01-01

    One of the most challenging problems of contemporary theoretical physics is the mathematically rigorous construction of a theory which describes gravitation and the other fundamental physical interactions within a common framework. The physical ideas which grew from attempts to develop such a theory require highly advanced mathematical methods and radically new physical concepts. This book presents different approaches to a rigorous unified description of quantum fields and gravity. It contains a carefully selected cross-section of lively discussions which took place in autumn 2010 at the fifth conference "Quantum field theory and gravity - Conceptual and mathematical advances in the search for a unified framework" in Regensburg, Germany. In the tradition of the other proceedings covering this series of conferences, a special feature of this book is the exposition of a wide variety of approaches, with the intention to facilitate a comparison. The book is mainly addressed to mathematicians and physicis...

  12. Binning metagenomic contigs by coverage and composition

    NARCIS (Netherlands)

    Alneberg, J.; Bjarnason, B.S.; Bruijn, de I.; Schirmer, M.; Quick, J.; Ijaz, U.Z.; Lahti, L.M.; Loman, N.J.; Andersson, A.F.; Quince, C.

    2014-01-01

    Shotgun sequencing enables the reconstruction of genomes from complex microbial communities, but because assembly does not reconstruct entire genomes, it is necessary to bin genome fragments. Here we present CONCOCT, a new algorithm that combines sequence composition and coverage across multiple

  13. Monitoring household waste recycling centres performance using mean bin weight analyses.

    Science.gov (United States)

    Maynard, Sarah; Cherrett, Tom; Waterson, Ben

    2009-02-01

    This paper describes a modelling approach used to investigate the significance of key factors (vehicle type, compaction type, site design, temporal effects) in influencing the variability in observed nett amenity bin weights produced by household waste recycling centres (HWRCs). This new method can help to quickly identify sites that are producing significantly lighter bins, enabling detailed back-end analyses to be efficiently targeted and best practice in HWRC operation identified. Tested on weigh ticket data from nine HWRCs across West Sussex, UK, the model suggests that compaction technique, vehicle type, month and site design explained 76% of the variability in the observed nett amenity weights. For each factor, a weighting coefficient was calculated to generate a predicted nett weight for each bin transaction and three sites were subsequently identified as having similar characteristics but returned significantly different mean nett bin weights. Waste and site audits were then conducted at the three sites to try and determine the possible sources of the remaining variability. Significant differences were identified in the proportions of contained waste (bagged), wood, and dry recyclables entering the amenity waste stream, particularly at one site where significantly less contaminated waste and dry recyclables were observed.

  14. Genetic patterns in European geometrid moths revealed by the Barcode Index Number (BIN system.

    Directory of Open Access Journals (Sweden)

    Axel Hausmann

    Full Text Available BACKGROUND: The geometrid moths of Europe are one of the best investigated insect groups in traditional taxonomy making them an ideal model group to test the accuracy of the Barcode Index Number (BIN system of BOLD (Barcode of Life Datasystems, a method that supports automated, rapid species delineation and identification. METHODOLOGY/PRINCIPAL FINDINGS: This study provides a DNA barcode library for 219 of the 249 European geometrid moth species (88% in five selected subfamilies. The data set includes COI sequences for 2130 specimens. Most species (93% were found to possess diagnostic barcode sequences at the European level while only three species pairs (3% were genetically indistinguishable in areas of sympatry. As a consequence, 97% of the European species we examined were unequivocally discriminated by barcodes within their natural areas of distribution. We found a 1:1 correspondence between BINs and traditionally recognized species for 67% of these species. Another 17% of the species (15 pairs, three triads shared BINs, while specimens from the remaining species (18% were divided among two or more BINs. Five of these species are mixtures, both sharing and splitting BINs. For 82% of the species with two or more BINs, the genetic splits involved allopatric populations, many of which have previously been hypothesized to represent distinct species or subspecies. CONCLUSIONS/SIGNIFICANCE: This study confirms the effectiveness of DNA barcoding as a tool for species identification and illustrates the potential of the BIN system to characterize formal genetic units independently of an existing classification. This suggests the system can be used to efficiently assess the biodiversity of large, poorly known assemblages of organisms. For the moths examined in this study, cases of discordance between traditionally recognized species and BINs arose from several causes including overlooked species, synonymy, and cases where DNA barcodes revealed

  15. Development of a tiered and binned genetic counseling model for informed consent in the era of multiplex testing for cancer susceptibility.

    Science.gov (United States)

    Bradbury, Angela R; Patrick-Miller, Linda; Long, Jessica; Powers, Jacquelyn; Stopfer, Jill; Forman, Andrea; Rybak, Christina; Mattie, Kristin; Brandt, Amanda; Chambers, Rachelle; Chung, Wendy K; Churpek, Jane; Daly, Mary B; Digiovanni, Laura; Farengo-Clark, Dana; Fetzer, Dominique; Ganschow, Pamela; Grana, Generosa; Gulden, Cassandra; Hall, Michael; Kohler, Lynne; Maxwell, Kara; Merrill, Shana; Montgomery, Susan; Mueller, Rebecca; Nielsen, Sarah; Olopade, Olufunmilayo; Rainey, Kimberly; Seelaus, Christina; Nathanson, Katherine L; Domchek, Susan M

    2015-06-01

    Multiplex genetic testing, including both moderate- and high-penetrance genes for cancer susceptibility, is associated with greater uncertainty than traditional testing, presenting challenges to informed consent and genetic counseling. We sought to develop a new model for informed consent and genetic counseling for four ongoing studies. Drawing from professional guidelines, literature, conceptual frameworks, and clinical experience, a multidisciplinary group developed a tiered-binned genetic counseling approach proposed to facilitate informed consent and improve outcomes of cancer susceptibility multiplex testing. In this model, tier 1 "indispensable" information is presented to all patients. More specific tier 2 information is provided to support variable informational needs among diverse patient populations. Clinically relevant information is "binned" into groups to minimize information overload, support informed decision making, and facilitate adaptive responses to testing. Seven essential elements of informed consent are provided to address the unique limitations, risks, and uncertainties of multiplex testing. A tiered-binned model for informed consent and genetic counseling has the potential to address the challenges of multiplex testing for cancer susceptibility and to support informed decision making and adaptive responses to testing. Future prospective studies including patient-reported outcomes are needed to inform how to best incorporate multiplex testing for cancer susceptibility into clinical practice.Genet Med 17 6, 485-492.

  16. Robotic vision system for random bin picking with dual-arm robots

    Directory of Open Access Journals (Sweden)

    Kang Sangseung

    2016-01-01

    Full Text Available Random bin picking is one of the most challenging industrial robotics applications available. It constitutes a complicated interaction between the vision system, robot, and control system. For a packaging operation requiring a pick-and-place task, the robot system utilized should be able to perform certain functions for recognizing the applicable target object from randomized objects in a bin. In this paper, we introduce a robotic vision system for bin picking using industrial dual-arm robots. The proposed system recognizes the best object from randomized target candidates based on stereo vision, and estimates the position and orientation of the object. It then sends the result to the robot control system. The system was developed for use in the packaging process of cell phone accessories using dual-arm robots.

  17. ATLAS (Automatic Tool for Local Assembly Structures) - A Comprehensive Infrastructure for Assembly, Annotation, and Genomic Binning of Metagenomic and Metaranscripomic Data

    Energy Technology Data Exchange (ETDEWEB)

    White, Richard A.; Brown, Joseph M.; Colby, Sean M.; Overall, Christopher C.; Lee, Joon-Yong; Zucker, Jeremy D.; Glaesemann, Kurt R.; Jansson, Georg C.; Jansson, Janet K.

    2017-03-02

    ATLAS (Automatic Tool for Local Assembly Structures) is a comprehensive multiomics data analysis pipeline that is massively parallel and scalable. ATLAS contains a modular analysis pipeline for assembly, annotation, quantification and genome binning of metagenomics and metatranscriptomics data and a framework for reference metaproteomic database construction. ATLAS transforms raw sequence data into functional and taxonomic data at the microbial population level and provides genome-centric resolution through genome binning. ATLAS provides robust taxonomy based on majority voting of protein coding open reading frames rolled-up at the contig level using modified lowest common ancestor (LCA) analysis. ATLAS provides robust taxonomy based on majority voting of protein coding open reading frames rolled-up at the contig level using modified lowest common ancestor (LCA) analysis. ATLAS is user-friendly, easy install through bioconda maintained as open-source on GitHub, and is implemented in Snakemake for modular customizable workflows.

  18. Osama bin Ladeni uus imidzh / Urmas Kiil

    Index Scriptorium Estoniae

    Kiil, Urmas

    2007-01-01

    Pärast kolm aastat kestnud pausi ilmus terroriorganisatsiooni al-Qaeda liider Osama bin Laden kahel korral taas maailma avalikkuse ette. Enamik asjatundjad on seisukohal, et maailma esiterroristi videopöördumised olid autentsed ja tõenäoliselt olid need salvestatud juulis või augustis

  19. Test Plan Addendum No. 1: Waste Isolation Pilot Plant bin-scale CH TRU waste tests

    International Nuclear Information System (INIS)

    Molecke, M.A.; Lappin, A.R.

    1990-12-01

    This document is the first major revision to the Test Plan: WIPP Bin-Scale CH TRU Waste Tests. Factors that make this revision necessary are described and justified in Section 1, and elaborated upon in Section 4. This addendum contains recommended estimates of, and details for: (1) The total separation of waste leaching/solubility tests from bin-scale gas tests, including preliminary details and quantities of leaching tests required for testing of Levels 1, 2, and 3 WIPP CH TRU wastes; (2) An initial description and quantification of bin-scale gas test Phase 0, added to provide a crucial tie to pretest waste characterization representatives and overall test statistical validation; (3) A revision to the number of test bins required for Phases 1 and 2 of the bin gas test program, and specification of the numbers of additional bin tests required for incorporating gas testing of Level 2 wastes into test Phase 3. Contingencies are stated for the total number of test bins required, both positive and negative, including the supporting assumptions, logic, and decision points. (4) Several other general test detail updates occurring since the Test Plan was approved and published in January, 1990. Possible impacts of recommended revisions included in this Addendum on WIPP site operations are called out and described. 56 refs., 12 tabs

  20. Deterministically swapping frequency-bin entanglement from photon-photon to atom-photon hybrid systems

    Science.gov (United States)

    Ou, Bao-Quan; Liu, Chang; Sun, Yuan; Chen, Ping-Xing

    2018-02-01

    Inspired by the recent developments of the research on the atom-photon quantum interface and energy-time entanglement between single-photon pulses, we are motivated to study the deterministic protocol for the frequency-bin entanglement of the atom-photon hybrid system, which is analogous to the frequency-bin entanglement between single-photon pulses. We show that such entanglement arises naturally in considering the interaction between a frequency-bin entangled single-photon pulse pair and a single atom coupled to an optical cavity, via straightforward atom-photon phase gate operations. Its anticipated properties and preliminary examples of its potential application in quantum networking are also demonstrated. Moreover, we construct a specific quantum entanglement witness tool to detect such extended frequency-bin entanglement from a reasonably general set of separable states, and prove its capability theoretically. We focus on the energy-time considerations throughout the analysis.

  1. The binning of metagenomic contigs for microbial physiology of mixed cultures.

    Science.gov (United States)

    Strous, Marc; Kraft, Beate; Bisdorf, Regina; Tegetmeyer, Halina E

    2012-01-01

    So far, microbial physiology has dedicated itself mainly to pure cultures. In nature, cross feeding and competition are important aspects of microbial physiology and these can only be addressed by studying complete communities such as enrichment cultures. Metagenomic sequencing is a powerful tool to characterize such mixed cultures. In the analysis of metagenomic data, well established algorithms exist for the assembly of short reads into contigs and for the annotation of predicted genes. However, the binning of the assembled contigs or unassembled reads is still a major bottleneck and required to understand how the overall metabolism is partitioned over different community members. Binning consists of the clustering of contigs or reads that apparently originate from the same source population. In the present study eight metagenomic samples from the same habitat, a laboratory enrichment culture, were sequenced. Each sample contained 13-23 Mb of assembled contigs and up to eight abundant populations. Binning was attempted with existing methods but they were found to produce poor results, were slow, dependent on non-standard platforms or produced errors. A new binning procedure was developed based on multivariate statistics of tetranucleotide frequencies combined with the use of interpolated Markov models. Its performance was evaluated by comparison of the results between samples with BLAST and in comparison to existing algorithms for four publicly available metagenomes and one previously published artificial metagenome. The accuracy of the new approach was comparable or higher than existing methods. Further, it was up to a 100 times faster. It was implemented in Java Swing as a complete open source graphical binning application available for download and further development (http://sourceforge.net/projects/metawatt).

  2. The binning of metagenomic contigs for microbial physiology of mixed cultures

    Directory of Open Access Journals (Sweden)

    Marc eStrous

    2012-12-01

    Full Text Available So far, microbial physiology has dedicated itself mainly to pure cultures. In nature, cross feeding and competition are important aspects of microbial physiology and these can only be addressed by studying complete communities such as enrichment cultures. Metagenomic sequencing is a powerful tool to characterize such mixed cultures. In the analysis of metagenomic data, well established algorithms exist for the assembly of short reads into contigs and for the annotation of predicted genes. However, the binning of the assembled contigs or unassembled reads is still a major bottleneck and required to understand how the overall metabolism is partitioned over different community members. Binning consists of the clustering of contigs or reads that apparently originate from the same source population.In the present study eight metagenomic samples originating from the same habitat, a laboratory enrichment culture, were sequenced. Each sample contained 13-23 Mb of assembled contigs and up to eight abundant populations. Binning was attempted with existing methods but they were found to produce poor results, were slow, dependent on non-standard platforms or produced errors. A new binning procedure was developed based on multivariate statistics of tetranucleotide frequencies combined with the use of interpolated Markov models. Its performance was evaluated by comparison of the results between samples with BLAST and in comparison to exisiting algorithms for four publicly available metagenomes and one previously published artificial metagenome. The accuracy of the new approach was comparable or higher than existing methods. Further, it was up to a hunderd times faster. It was implemented in Java Swing as a complete open source graphical binning application available for download and further development (http://sourceforge.net/projects/metawatt.

  3. Optimization of Network Topology in Computer-Aided Detection Schemes Using Phased Searching with NEAT in a Time-Scaled Framework.

    Science.gov (United States)

    Tan, Maxine; Pu, Jiantao; Zheng, Bin

    2014-01-01

    In the field of computer-aided mammographic mass detection, many different features and classifiers have been tested. Frequently, the relevant features and optimal topology for the artificial neural network (ANN)-based approaches at the classification stage are unknown, and thus determined by trial-and-error experiments. In this study, we analyzed a classifier that evolves ANNs using genetic algorithms (GAs), which combines feature selection with the learning task. The classifier named "Phased Searching with NEAT in a Time-Scaled Framework" was analyzed using a dataset with 800 malignant and 800 normal tissue regions in a 10-fold cross-validation framework. The classification performance measured by the area under a receiver operating characteristic (ROC) curve was 0.856 ± 0.029. The result was also compared with four other well-established classifiers that include fixed-topology ANNs, support vector machines (SVMs), linear discriminant analysis (LDA), and bagged decision trees. The results show that Phased Searching outperformed the LDA and bagged decision tree classifiers, and was only significantly outperformed by SVM. Furthermore, the Phased Searching method required fewer features and discarded superfluous structure or topology, thus incurring a lower feature computational and training and validation time requirement. Analyses performed on the network complexities evolved by Phased Searching indicate that it can evolve optimal network topologies based on its complexification and simplification parameter selection process. From the results, the study also concluded that the three classifiers - SVM, fixed-topology ANN, and Phased Searching with NeuroEvolution of Augmenting Topologies (NEAT) in a Time-Scaled Framework - are performing comparably well in our mammographic mass detection scheme.

  4. Improving the Bin Packing Heuristic through Grammatical Evolution Based on Swarm Intelligence

    Directory of Open Access Journals (Sweden)

    Marco Aurelio Sotelo-Figueroa

    2014-01-01

    Full Text Available In recent years Grammatical Evolution (GE has been used as a representation of Genetic Programming (GP which has been applied to many optimization problems such as symbolic regression, classification, Boolean functions, constructed problems, and algorithmic problems. GE can use a diversity of searching strategies including Swarm Intelligence (SI. Particle Swarm Optimisation (PSO is an algorithm of SI that has two main problems: premature convergence and poor diversity. Particle Evolutionary Swarm Optimization (PESO is a recent and novel algorithm which is also part of SI. PESO uses two perturbations to avoid PSO’s problems. In this paper we propose using PESO and PSO in the frame of GE as strategies to generate heuristics that solve the Bin Packing Problem (BPP; it is possible however to apply this methodology to other kinds of problems using another Grammar designed for that problem. A comparison between PESO, PSO, and BPP’s heuristics is performed through the nonparametric Friedman test. The main contribution of this paper is proposing a Grammar to generate online and offline heuristics depending on the test instance trying to improve the heuristics generated by other grammars and humans; it also proposes a way to implement different algorithms as search strategies in GE like PESO to obtain better results than those obtained by PSO.

  5. A robust and accurate binning algorithm for metagenomic sequences with arbitrary species abundance ratio.

    Science.gov (United States)

    Leung, Henry C M; Yiu, S M; Yang, Bin; Peng, Yu; Wang, Yi; Liu, Zhihua; Chen, Jingchi; Qin, Junjie; Li, Ruiqiang; Chin, Francis Y L

    2011-06-01

    With the rapid development of next-generation sequencing techniques, metagenomics, also known as environmental genomics, has emerged as an exciting research area that enables us to analyze the microbial environment in which we live. An important step for metagenomic data analysis is the identification and taxonomic characterization of DNA fragments (reads or contigs) resulting from sequencing a sample of mixed species. This step is referred to as 'binning'. Binning algorithms that are based on sequence similarity and sequence composition markers rely heavily on the reference genomes of known microorganisms or phylogenetic markers. Due to the limited availability of reference genomes and the bias and low availability of markers, these algorithms may not be applicable in all cases. Unsupervised binning algorithms which can handle fragments from unknown species provide an alternative approach. However, existing unsupervised binning algorithms only work on datasets either with balanced species abundance ratios or rather different abundance ratios, but not both. In this article, we present MetaCluster 3.0, an integrated binning method based on the unsupervised top--down separation and bottom--up merging strategy, which can bin metagenomic fragments of species with very balanced abundance ratios (say 1:1) to very different abundance ratios (e.g. 1:24) with consistently higher accuracy than existing methods. MetaCluster 3.0 can be downloaded at http://i.cs.hku.hk/~alse/MetaCluster/.

  6. Regulation of the interaction between the neuronal BIN1 isoform 1 and Tau proteins - role of the SH3 domain.

    Science.gov (United States)

    Malki, Idir; Cantrelle, François-Xavier; Sottejeau, Yoann; Lippens, Guy; Lambert, Jean-Charles; Landrieu, Isabelle

    2017-10-01

    Bridging integrator 1 (bin1) gene is a genetic determinant of Alzheimer's disease (AD) and has been reported to modulate Alzheimer's pathogenesis through pathway(s) involving Tau. The functional impact of Tau/BIN1 interaction as well as the molecular details of this interaction are still not fully resolved. As a consequence, how BIN1 through its interaction with Tau affects AD risk is also still not determined. To progress in this understanding, interaction of Tau with two BIN1 isoforms was investigated using Nuclear Magnetic Resonance spectroscopy. 1 H, 15 N spectra showed that the C-terminal SH3 domain of BIN1 isoform 1 (BIN1Iso1) is not mobile in solution but locked with the core of the protein. In contrast, the SH3 domain of BIN1 isoform 9 (BIN1Iso9) behaves as an independent mobile domain. This reveals an equilibrium between close and open conformations for the SH3 domain. Interestingly, a 334-376 peptide from the clathrin and AP-2-binding domain (CLAP) domain of BIN1Iso1, which contains a SH3-binding site, is able to compete with BIN1-SH3 intramolecular interaction. For both BIN1 isoforms, the SH3 domain can interact with Tau(210-240) sequence. Tau(210-240) peptide can indeed displace the intramolecular interaction of the BIN1-SH3 of BIN1Iso1 and form a complex with the released domain. The measured K d were in agreement with a stronger affinity of Tau peptide. Both CLAP and Tau peptides occupied the same surface on the BIN1-SH3 domain, showing that their interaction is mutually exclusive. These results emphasize an additional level of complexity in the regulation of the interaction between BIN1 and Tau dependent of the BIN1 isoforms. © 2017 Federation of European Biochemical Societies.

  7. Exploiting jet binning to identify the initial state of high-mass resonances

    Science.gov (United States)

    Ebert, Markus A.; Liebler, Stefan; Moult, Ian; Stewart, Iain W.; Tackmann, Frank J.; Tackmann, Kerstin; Zeune, Lisa

    2016-09-01

    If a new high-mass resonance is discovered at the Large Hadron Collider, model-independent techniques to identify the production mechanism will be crucial to understand its nature and effective couplings to Standard Model particles. We present a powerful and model-independent method to infer the initial state in the production of any high-mass color-singlet system by using a tight veto on accompanying hadronic jets to divide the data into two mutually exclusive event samples (jet bins). For a resonance of several hundred GeV, the jet binning cut needed to discriminate quark and gluon initial states is in the experimentally accessible range of several tens of GeV. It also yields comparable cross sections for both bins, making this method viable already with the small event samples available shortly after a discovery. Theoretically, the method is made feasible by utilizing an effective field theory setup to compute the jet cut dependence precisely and model independently and to systematically control all sources of theoretical uncertainties in the jet binning, as well as their correlations. We use a 750 GeV scalar resonance as an example to demonstrate the viability of our method.

  8. Exploiting jet binning to identify the initial state of high-mass resonances

    International Nuclear Information System (INIS)

    Ebert, Markus A.; Liebler, Stefan; Tackmann, Frank J.; Tackmann, Kerstin; Moult, Ian; Stewart, Iain W.; Zeune, Lisa

    2016-05-01

    If a new high-mass resonance is discovered at the Large Hadron Collider, model-independent techniques to identify the production mechanism will be crucial to understand its nature and effective couplings to Standard Model particles. We present a powerful and model-independent method to infer the initial state in the production of any high-mass color-singlet system by using a tight veto on accompanying hadronic jets to divide the data into two mutually exclusive event samples (jet bins). For a resonance of several hundred GeV, the jet binning cut needed to discriminate quark and gluon initial states is in the experimentally accessible range of several tens of GeV. It also yields comparable cross sections for both bins, making this method viable already with the small event samples available shortly after a discovery. Theoretically, the method is made feasible by utilizing an effective field theory setup to compute the jet cut dependence precisely and model-independently and to systematically control all sources of theoretical uncertainties in the jet binning, as well as their correlations. We use a 750 GeV scalar resonance as an example to demonstrate the viability of our method.

  9. Benchmarking motion planning algorithms for bin-picking applications

    DEFF Research Database (Denmark)

    Iversen, Thomas Fridolin; Ellekilde, Lars-Peter

    2017-01-01

    Purpose For robot motion planning there exists a large number of different algorithms, each appropriate for a certain domain, and the right choice of planner depends on the specific use case. The purpose of this paper is to consider the application of bin picking and benchmark a set of motion...... planning algorithms to identify which are most suited in the given context. Design/methodology/approach The paper presents a selection of motion planning algorithms and defines benchmarks based on three different bin-picking scenarios. The evaluation is done based on a fixed set of tasks, which are planned...... and executed on a real and a simulated robot. Findings The benchmarking shows a clear difference between the planners and generally indicates that algorithms integrating optimization, despite longer planning time, perform better due to a faster execution. Originality/value The originality of this work lies...

  10. Fungal volatiles associated with moldy grain in ventilated and non-ventilated bin-stored wheat.

    Science.gov (United States)

    Sinha, R N; Tuma, D; Abramson, D; Muir, W E

    1988-01-01

    The fungal odor compounds 3-methyl-1-butanol, 1-octen-3-ol and 3-octanone were monitored in nine experimental bins in Winnipeg, Manitoba containing a hard red spring wheat during the autumn, winter and summer seasons of 1984-85. Quality changes were associated with seed-borne microflora and moisture content in both ventilated and non-ventilated bins containing wheat of 15.6 and 18.2% initial moisture content. All three odor compounds occurred in considerably greater amounts in bulk wheat in non-ventilated than in ventilated bins, particularly in those with wheat having 18.2% moisture content. The presence of these compounds usually coincided with infection of the seeds by the fungi Alternaria alternata (Fr.) Keissler, Aspergillus repens DeBarry, A. versicolor (Vuill.) Tiraboschi, Penicillium crustosum Thom, P. oxalicum Currie and Thom, P. aurantiogriesum Dierckx, and P. citrinum Thom. High production of all three odor compounds in damp wheat stored in non-ventilated bins was associated with heavy fungal infection of the seeds and reduction in seed germinability. High initial moisture content of the harvested grain accelerated the production of all three fungal volatiles in non-ventilated bins.

  11. Afghanistan, the Taliban, and Osama bin Laden: The Background to September 11

    Science.gov (United States)

    Social Education, 2011

    2011-01-01

    On May 1, 2011, a group of U.S. soldiers boarded helicopters at a base in Afghanistan, hoping to find a man named Osama bin Laden. Bin Laden, the leader of the al Qaeda terrorist network, was responsible for a number of terrorist attacks around the world, including those of September 11, 2001, that killed nearly 3,000 people in the United States.…

  12. High-visibility time-bin entanglement for testing chained Bell inequalities

    Science.gov (United States)

    Tomasin, Marco; Mantoan, Elia; Jogenfors, Jonathan; Vallone, Giuseppe; Larsson, Jan-Åke; Villoresi, Paolo

    2017-03-01

    The violation of Bell's inequality requires a well-designed experiment to validate the result. In experiments using energy-time and time-bin entanglement, initially proposed by Franson in 1989, there is an intrinsic loophole due to the high postselection. To obtain a violation in this type of experiment, a chained Bell inequality must be used. However, the local realism bound requires a high visibility in excess of 94.63% in the time-bin entangled state. In this work, we show how such a high visibility can be reached in order to violate a chained Bell inequality with six, eight, and ten terms.

  13. Histogram bin width selection for time-dependent Poisson processes

    International Nuclear Information System (INIS)

    Koyama, Shinsuke; Shinomoto, Shigeru

    2004-01-01

    In constructing a time histogram of the event sequences derived from a nonstationary point process, we wish to determine the bin width such that the mean squared error of the histogram from the underlying rate of occurrence is minimized. We find that the optimal bin widths obtained for a doubly stochastic Poisson process and a sinusoidally regulated Poisson process exhibit different scaling relations with respect to the number of sequences, time scale and amplitude of rate modulation, but both diverge under similar parametric conditions. This implies that under these conditions, no determination of the time-dependent rate can be made. We also apply the kernel method to these point processes, and find that the optimal kernels do not exhibit any critical phenomena, unlike the time histogram method

  14. Histogram bin width selection for time-dependent Poisson processes

    Energy Technology Data Exchange (ETDEWEB)

    Koyama, Shinsuke; Shinomoto, Shigeru [Department of Physics, Graduate School of Science, Kyoto University, Sakyo-ku, Kyoto 606-8502 (Japan)

    2004-07-23

    In constructing a time histogram of the event sequences derived from a nonstationary point process, we wish to determine the bin width such that the mean squared error of the histogram from the underlying rate of occurrence is minimized. We find that the optimal bin widths obtained for a doubly stochastic Poisson process and a sinusoidally regulated Poisson process exhibit different scaling relations with respect to the number of sequences, time scale and amplitude of rate modulation, but both diverge under similar parametric conditions. This implies that under these conditions, no determination of the time-dependent rate can be made. We also apply the kernel method to these point processes, and find that the optimal kernels do not exhibit any critical phenomena, unlike the time histogram method.

  15. Propagation and survival of frequency-bin entangled photons in metallic nanostructures

    Directory of Open Access Journals (Sweden)

    Olislager Laurent

    2015-01-01

    Full Text Available We report on the design of two plasmonic nanostructures and the propagation of frequency-bin entangled photons through them. The experimental findings clearly show the robustness of frequency-bin entanglement, which survives after interactions with both a hybrid plasmo-photonic structure, and a nano-pillar array. These results confirm that quantum states can be encoded into the collective motion of a many-body electronic system without demolishing their quantum nature, and pave the way towards applications of plasmonic structures in quantum information.

  16. Utilization of deletion bins to anchor and order sequences along the wheat 7B chromosome.

    Science.gov (United States)

    Belova, Tatiana; Grønvold, Lars; Kumar, Ajay; Kianian, Shahryar; He, Xinyao; Lillemo, Morten; Springer, Nathan M; Lien, Sigbjørn; Olsen, Odd-Arne; Sandve, Simen R

    2014-09-01

    A total of 3,671 sequence contigs and scaffolds were mapped to deletion bins on wheat chromosome 7B providing a foundation for developing high-resolution integrated physical map for this chromosome. Bread wheat (Triticum aestivum L.) has a large, complex and highly repetitive genome which is challenging to assemble into high quality pseudo-chromosomes. As part of the international effort to sequence the hexaploid bread wheat genome by the international wheat genome sequencing consortium (IWGSC) we are focused on assembling a reference sequence for chromosome 7B. The successful completion of the reference chromosome sequence is highly dependent on the integration of genetic and physical maps. To aid the integration of these two types of maps, we have constructed a high-density deletion bin map of chromosome 7B. Using the 270 K Nimblegen comparative genomic hybridization (CGH) array on a set of cv. Chinese spring deletion lines, a total of 3,671 sequence contigs and scaffolds (~7.8 % of chromosome 7B physical length) were mapped into nine deletion bins. Our method of genotyping deletions on chromosome 7B relied on a model-based clustering algorithm (Mclust) to accurately predict the presence or absence of a given genomic sequence in a deletion line. The bin mapping results were validated using three different approaches, viz. (a) PCR-based amplification of randomly selected bin mapped sequences (b) comparison with previously mapped ESTs and (c) comparison with a 7B genetic map developed in the present study. Validation of the bin mapping results suggested a high accuracy of the assignment of 7B sequence contigs and scaffolds to the 7B deletion bins.

  17. Unsupervised binning of environmental genomic fragments based on an error robust selection of l-mers.

    Science.gov (United States)

    Yang, Bin; Peng, Yu; Leung, Henry Chi-Ming; Yiu, Siu-Ming; Chen, Jing-Chi; Chin, Francis Yuk-Lun

    2010-04-16

    With the rapid development of genome sequencing techniques, traditional research methods based on the isolation and cultivation of microorganisms are being gradually replaced by metagenomics, which is also known as environmental genomics. The first step, which is still a major bottleneck, of metagenomics is the taxonomic characterization of DNA fragments (reads) resulting from sequencing a sample of mixed species. This step is usually referred as "binning". Existing binning methods are based on supervised or semi-supervised approaches which rely heavily on reference genomes of known microorganisms and phylogenetic marker genes. Due to the limited availability of reference genomes and the bias and instability of marker genes, existing binning methods may not be applicable in many cases. In this paper, we present an unsupervised binning method based on the distribution of a carefully selected set of l-mers (substrings of length l in DNA fragments). From our experiments, we show that our method can accurately bin DNA fragments with various lengths and relative species abundance ratios without using any reference and training datasets. Another feature of our method is its error robustness. The binning accuracy decreases by less than 1% when the sequencing error rate increases from 0% to 5%. Note that the typical sequencing error rate of existing commercial sequencing platforms is less than 2%. We provide a new and effective tool to solve the metagenome binning problem without using any reference datasets or markers information of any known reference genomes (species). The source code of our software tool, the reference genomes of the species for generating the test datasets and the corresponding test datasets are available at http://i.cs.hku.hk/~alse/MetaCluster/.

  18. Comparison of an alternative and existing binning methods to reduce the acquisition duration of 4D PET/CT

    International Nuclear Information System (INIS)

    Didierlaurent, David; Ribes, Sophie; Caselles, Olivier; Jaudet, Cyril; Dierickx, Lawrence O.; Zerdoud, Slimane; Brillouet, Severine; Weits, Kathleen; Batatia, Hadj; Courbon, Frédéric

    2014-01-01

    Purpose: Respiratory motion is a source of artifacts that reduce image quality in PET. Four dimensional (4D) PET/CT is one approach to overcome this problem. Existing techniques to limiting the effects of respiratory motions are based on prospective phase binning which requires a long acquisition duration (15–25 min). This time is uncomfortable for the patients and limits the clinical exploitation of 4D PET/CT. In this work, the authors evaluated an existing method and an alternative retrospective binning method to reduce the acquisition duration of 4D PET/CT. Methods: The authors studied an existing mixed-amplitude binning (MAB) method and an alternative binning method by mixed-phases (MPhB). Before implementing MPhB, they analyzed the regularity of the breathing patterns in patients. They studied the breathing signal drift and missing CT slices that could be challenging for implementing MAB. They compared the performance of MAB and MPhB with current binning methods to measure the maximum uptake, internal volume, and maximal range of tumor motion. Results: MPhB can be implemented depending on an optimal phase (in average, the exhalation peak phase −4.1% of the entire breathing cycle duration). Signal drift of patients was in average 35% relative to the breathing amplitude. Even after correcting this drift, MAB was feasible in 4D CT for only 64% of patients. No significant differences appeared between the different binning methods to measure the maximum uptake, internal volume, and maximal range of tumor motion. The authors also determined the inaccuracies of MAB and MPhB to measure the maximum amplitude of tumor motion with three bins (less than 3 mm for movement inferior to 12 mm, up to 6.4 mm for a 21 mm movement). Conclusions: The authors proposed an alternative binning method by mixed-phase binning that halves the acquisition duration of 4D PET/CT. Mixed-amplitude binning was challenging because of signal drift and missing CT slices. They showed that more

  19. Demonstration of analyzers for multimode photonic time-bin qubits

    Science.gov (United States)

    Jin, Jeongwan; Agne, Sascha; Bourgoin, Jean-Philippe; Zhang, Yanbao; Lütkenhaus, Norbert; Jennewein, Thomas

    2018-04-01

    We demonstrate two approaches for unbalanced interferometers as time-bin qubit analyzers for quantum communication, robust against mode distortions and polarization effects as expected from free-space quantum communication systems including wavefront deformations, path fluctuations, pointing errors, and optical elements. Despite strong spatial and temporal distortions of the optical mode of a time-bin qubit, entangled with a separate polarization qubit, we verify entanglement using the Negative Partial Transpose, with the measured visibility of up to 0.85 ±0.01 . The robustness of the analyzers is further demonstrated for various angles of incidence up to 0 .2∘ . The output of the interferometers is coupled into multimode fiber yielding a high system throughput of 0.74. Therefore, these analyzers are suitable and efficient for quantum communication over multimode optical channels.

  20. Vision guided robot bin picking of cylindrical objects

    DEFF Research Database (Denmark)

    Christensen, Georg Kronborg; Dyhr-Nielsen, Carsten

    1997-01-01

    In order to achieve increased flexibility on robotic production lines an investigation of the rovbot bin-picking problem is presented. In the paper, the limitations related to previous attempts to solve the problem are pointed uot and a set of innovative methods are presented. The main elements...

  1. Market Dominance and Search Quality in the Search Engine Market

    NARCIS (Netherlands)

    Lianos, I.; Motchenkova, E.I.

    2013-01-01

    We analyze a search engine market from a law and economics perspective and incorporate the choice of quality-improving innovations by a search engine platform in a two-sided model of Internet search engine. In the proposed framework, we first discuss the legal issues the search engine market raises

  2. Smart Bin: Internet-of-Things Garbage Monitoring System

    Directory of Open Access Journals (Sweden)

    Mustafa M.R

    2017-01-01

    Full Text Available This work introduces the design and development of smart green environment of garbage monitoring system by measuring the garbage level in real time and to alert the municipality where never the bin is full based on the types of garbage. The proposed system consisted the ultrasonic sensors which measure the garbage level, an ARM microcontroller which controls system operation whereas everything will be connected to ThingSpeak. This work demonstrates a system that allows the waste management to monitor based on the level of the garbage depth inside the dustbin. The system shows the status of different four types of garbage; domestic waste, paper, glass and plastic through LCD and ThingSpeak in a real time to store the data for future use and analysis, such as prediction of peak level of garbage bin fullness. It is expected that this system can create greener environment by monitoring and controlling the collection of garbage smartly through Internet-of-Things.

  3. Quantum secret sharing based on modulated high-dimensional time-bin entanglement

    International Nuclear Information System (INIS)

    Takesue, Hiroki; Inoue, Kyo

    2006-01-01

    We propose a scheme for quantum secret sharing (QSS) that uses a modulated high-dimensional time-bin entanglement. By modulating the relative phase randomly by {0,π}, a sender with the entanglement source can randomly change the sign of the correlation of the measurement outcomes obtained by two distant recipients. The two recipients must cooperate if they are to obtain the sign of the correlation, which is used as a secret key. We show that our scheme is secure against intercept-and-resend (IR) and beam splitting attacks by an outside eavesdropper thanks to the nonorthogonality of high-dimensional time-bin entangled states. We also show that a cheating attempt based on an IR attack by one of the recipients can be detected by changing the dimension of the time-bin entanglement randomly and inserting two 'vacant' slots between the packets. Then, cheating attempts can be detected by monitoring the count rate in the vacant slots. The proposed scheme has better experimental feasibility than previously proposed entanglement-based QSS schemes

  4. Using a combination of binning strategies and taxonomic approaches to unravel the anaerobic digestion microbiome

    DEFF Research Database (Denmark)

    Campanaro, Stefano; Treu, Laura; Kougias, Panagiotis

    of scaffolds comprehensive of thousands genome sequences, but the binning of these scaffolds into OTUs representative of microbial genomes is still challenging. In the attempt to obtain a deep characterization of the anaerobic digestion microbiome, different metagenomic binning approaches were integrated...

  5. A Framework for Similarity Search with Space-Time Tradeoffs using Locality Sensitive Filtering

    DEFF Research Database (Denmark)

    Christiani, Tobias Lybecker

    2017-01-01

    that satisfies certain locality-sensitivity properties, we can construct a dynamic data structure that solves the approximate near neighbor problem in $d$-dimensional space with query time $dn^{\\rho_q + o(1)}$, update time $dn^{\\rho_u + o(1)}$, and space usage $dn + n^{1 + \\rho_u + o(1)}$ where $n$ denotes......We present a framework for similarity search based on Locality-Sensitive Filtering~(LSF),generalizing the Indyk-Motwani (STOC 1998) Locality-Sensitive Hashing~(LSH) framework to support space-time tradeoffs. Given a family of filters, defined as a distribution over pairs of subsets of space...... the number of points in the data structure.The space-time tradeoff is tied to the tradeoff between query time and update time (insertions/deletions), controlled by the exponents $\\rho_q, \\rho_u$ that are determined by the filter family. \\\\ Locality-sensitive filtering was introduced by Becker et al. (SODA...

  6. Search costs and efficiency : Do unemployed workers search enough?

    NARCIS (Netherlands)

    Gautier, Pieter A.; Moraga González, José; Wolthoff, Ronald P.

    Many labor market policies affect the marginal benefits and costs of job search. The impact and desirability of such policies depend on the distribution of search costs. In this paper, we provide an equilibrium framework for identifying the distribution of search costs and we apply it to the Dutch

  7. Optimizing the search for transiting planets in long time series

    Science.gov (United States)

    Ofir, Aviv

    2014-01-01

    Context. Transit surveys, both ground- and space-based, have already accumulated a large number of light curves that span several years. Aims: The search for transiting planets in these long time series is computationally intensive. We wish to optimize the search for both detection and computational efficiencies. Methods: We assume that the searched systems can be described well by Keplerian orbits. We then propagate the effects of different system parameters to the detection parameters. Results: We show that the frequency information content of the light curve is primarily determined by the duty cycle of the transit signal, and thus the optimal frequency sampling is found to be cubic and not linear. Further optimization is achieved by considering duty-cycle dependent binning of the phased light curve. By using the (standard) BLS, one is either fairly insensitive to long-period planets or less sensitive to short-period planets and computationally slower by a significant factor of ~330 (for a 3 yr long dataset). We also show how the physical system parameters, such as the host star's size and mass, directly affect transit detection. This understanding can then be used to optimize the search for every star individually. Conclusions: By considering Keplerian dynamics explicitly rather than implicitly one can optimally search the BLS parameter space. The presented Optimal BLS enhances the detectability of both very short and very long period planets, while allowing such searches to be done with much reduced resources and time. The Matlab/Octave source code for Optimal BLS is made available. The MATLAB code is only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (ftp://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/561/A138

  8. Heuristics for the Variable Sized Bin Packing Problem Using a Hybrid P-System and CUDA Architecture

    OpenAIRE

    AlEnezi, Qadha'a; AboElFotoh, Hosam; AlBdaiwi, Bader; AlMulla, Mohammad Ali

    2016-01-01

    The Variable Sized Bin Packing Problem has a wide range of application areas including packing, scheduling, and manufacturing. Given a list of items and variable sized bin types, the objective is to minimize the total size of the used bins. This problem is known to be NP-hard. In this article, we present two new heuristics for solving the problem using a new variation of P systems with active membranes, which we call a hybrid P system, implemented in CUDA. Our hybrid P-system model allows usi...

  9. A Fast Framework for Abrupt Change Detection Based on Binary Search Trees and Kolmogorov Statistic

    Science.gov (United States)

    Qi, Jin-Peng; Qi, Jie; Zhang, Qing

    2016-01-01

    Change-Point (CP) detection has attracted considerable attention in the fields of data mining and statistics; it is very meaningful to discuss how to quickly and efficiently detect abrupt change from large-scale bioelectric signals. Currently, most of the existing methods, like Kolmogorov-Smirnov (KS) statistic and so forth, are time-consuming, especially for large-scale datasets. In this paper, we propose a fast framework for abrupt change detection based on binary search trees (BSTs) and a modified KS statistic, named BSTKS (binary search trees and Kolmogorov statistic). In this method, first, two binary search trees, termed as BSTcA and BSTcD, are constructed by multilevel Haar Wavelet Transform (HWT); second, three search criteria are introduced in terms of the statistic and variance fluctuations in the diagnosed time series; last, an optimal search path is detected from the root to leaf nodes of two BSTs. The studies on both the synthetic time series samples and the real electroencephalograph (EEG) recordings indicate that the proposed BSTKS can detect abrupt change more quickly and efficiently than KS, t-statistic (t), and Singular-Spectrum Analyses (SSA) methods, with the shortest computation time, the highest hit rate, the smallest error, and the highest accuracy out of four methods. This study suggests that the proposed BSTKS is very helpful for useful information inspection on all kinds of bioelectric time series signals. PMID:27413364

  10. A Fast Framework for Abrupt Change Detection Based on Binary Search Trees and Kolmogorov Statistic.

    Science.gov (United States)

    Qi, Jin-Peng; Qi, Jie; Zhang, Qing

    2016-01-01

    Change-Point (CP) detection has attracted considerable attention in the fields of data mining and statistics; it is very meaningful to discuss how to quickly and efficiently detect abrupt change from large-scale bioelectric signals. Currently, most of the existing methods, like Kolmogorov-Smirnov (KS) statistic and so forth, are time-consuming, especially for large-scale datasets. In this paper, we propose a fast framework for abrupt change detection based on binary search trees (BSTs) and a modified KS statistic, named BSTKS (binary search trees and Kolmogorov statistic). In this method, first, two binary search trees, termed as BSTcA and BSTcD, are constructed by multilevel Haar Wavelet Transform (HWT); second, three search criteria are introduced in terms of the statistic and variance fluctuations in the diagnosed time series; last, an optimal search path is detected from the root to leaf nodes of two BSTs. The studies on both the synthetic time series samples and the real electroencephalograph (EEG) recordings indicate that the proposed BSTKS can detect abrupt change more quickly and efficiently than KS, t-statistic (t), and Singular-Spectrum Analyses (SSA) methods, with the shortest computation time, the highest hit rate, the smallest error, and the highest accuracy out of four methods. This study suggests that the proposed BSTKS is very helpful for useful information inspection on all kinds of bioelectric time series signals.

  11. INTERFACING GOOGLE SEARCH ENGINE TO CAPTURE USER WEB SEARCH BEHAVIOR

    OpenAIRE

    Fadhilah Mat Yamin; T. Ramayah

    2013-01-01

    The behaviour of the searcher when using the search engine especially during the query formulation is crucial. Search engines capture users’ activities in the search log, which is stored at the search engine server. Due to the difficulty of obtaining this search log, this paper proposed and develops an interface framework to interface a Google search engine. This interface will capture users’ queries before redirect them to Google. The analysis of the search log will show that users are utili...

  12. Discovering bin-Laden’s Replacement in al-Qaeda, using Social Network Analysis: A Methodological Investigation

    Directory of Open Access Journals (Sweden)

    Edith Wu

    2014-02-01

    Full Text Available The removal of Osama bin-Laden created a leadership void within al-Qaeda. Despite the group’s autonomous cell structure, an authorative figure remains essential for promoting and disseminating al-Qaeda’s ideology. An appropriate replacement should exhibit traits comparable to bin-Laden and have similar positioning within the structure of the group. Using a media-based sample and social network analysis, this study attempts to uncover the most probable successor for bin-Laden by examining the dynamics within al-Qaeda. The results indicate how the differential embeddedness of al-Qaeda members affects social capital, which in turn provides insights for leadership potiential.

  13. GeneBins: a database for classifying gene expression data, with application to plant genome arrays

    Directory of Open Access Journals (Sweden)

    Weiller Georg

    2007-03-01

    Full Text Available Abstract Background To interpret microarray experiments, several ontological analysis tools have been developed. However, current tools are limited to specific organisms. Results We developed a bioinformatics system to assign the probe set sequences of any organism to a hierarchical functional classification modelled on KEGG ontology. The GeneBins database currently supports the functional classification of expression data from four Affymetrix arrays; Arabidopsis thaliana, Oryza sativa, Glycine max and Medicago truncatula. An online analysis tool to identify relevant functions is also provided. Conclusion GeneBins provides resources to interpret gene expression results from microarray experiments. It is available at http://bioinfoserver.rsbs.anu.edu.au/utils/GeneBins/

  14. Klasifikasi Ilmu Pengetahuan Dalam Perspektif Jābir Bin Ḥayyān

    Directory of Open Access Journals (Sweden)

    Asep N. Musadad

    2015-12-01

    Full Text Available Abstract : The central purpose of this article is to provide a preliminary exploration on epistemological background of the classical Islamic sciences through the investigation on the classification of knowledge. One of the earliest exponent to turn to this problem is Jābir bin Ḥayyān (Geber (721 - 815 AD, known as the Father of Arabic and – indirectly – Latin Alchemy. Start on describing  Jābir’s  profile  and  his  significance  in  Islamic  philosophy,  this  article  discusses the  classification  of  knowledge  according  to  him  in  his  book  “Kitāb  al-Ḥudūd”  (Book  of Limits, in which he make his own classification of various knowledge. It finally deals with the philosophical basis of the classification and the intellectual perspective of its author. Keywords : Jabir bin Hayyan, classification of knowledge, Islamic philosophy, natural sciences.   Abstrak : Artikel ini bertujuan untuk melakukan eksplorasi singkat terkait latar epistemologis dalam pengetahuan  Islam  klasik  melalui  analisis  terhadap  konsep  klasifikasi  ilmu  pengetahuan. Salah satu eksponen awal yang berbicara hal tersebut adalah Jābir bin Ḥayyān (Geber (721 - 815 M, dikenal sebagai Bapak Ilmu Kimia Arab dan – secara tidak langsung – Eropa-Latin. Diawali  dengan  penjelasan  tentang  signifikansi  Jābir  bin  Ḥayyān  dalam  wacana  filsafat Islam,  artikel  ini  mendiskusikan  klasifikasi  ilmu  pengetahuan  dalam  perspektifnya  yang terdapat  dalam  karyanya,  “Kitāb  al-Ḥudūd”  (Buku  tentang  Batas-Batas,  yang  membuat klasifikasi versinya sendiri dari berbagai macam ilmu pengetahuan. Pada akhirnya, tulisan ini juga akan menjelaskan basis filosofis dari klasifikasi tersebut dan perspektif intelektual pembuatnya. Kata-Kata Kunci : Jabir bin Hayyan, klasifikasi pengetahuan, filsafat Islam, ilmu-ilmu alam.

  15. SA-Search: a web tool for protein structure mining based on a Structural Alphabet.

    Science.gov (United States)

    Guyon, Frédéric; Camproux, Anne-Claude; Hochez, Joëlle; Tufféry, Pierre

    2004-07-01

    SA-Search is a web tool that can be used to mine for protein structures and extract structural similarities. It is based on a hidden Markov model derived Structural Alphabet (SA) that allows the compression of three-dimensional (3D) protein conformations into a one-dimensional (1D) representation using a limited number of prototype conformations. Using such a representation, classical methods developed for amino acid sequences can be employed. Currently, SA-Search permits the performance of fast 3D similarity searches such as the extraction of exact words using a suffix tree approach, and the search for fuzzy words viewed as a simple 1D sequence alignment problem. SA-Search is available at http://bioserv.rpbs.jussieu.fr/cgi-bin/SA-Search.

  16. Markov chain Monte Carlo linkage analysis: effect of bin width on the probability of linkage.

    Science.gov (United States)

    Slager, S L; Juo, S H; Durner, M; Hodge, S E

    2001-01-01

    We analyzed part of the Genetic Analysis Workshop (GAW) 12 simulated data using Monte Carlo Markov chain (MCMC) methods that are implemented in the computer program Loki. The MCMC method reports the "probability of linkage" (PL) across the chromosomal regions of interest. The point of maximum PL can then be taken as a "location estimate" for the location of the quantitative trait locus (QTL). However, Loki does not provide a formal statistical test of linkage. In this paper, we explore how the bin width used in the calculations affects the max PL and the location estimate. We analyzed age at onset (AO) and quantitative trait number 5, Q5, from 26 replicates of the general simulated data in one region where we knew a major gene, MG5, is located. For each trait, we found the max PL and the corresponding location estimate, using four different bin widths. We found that bin width, as expected, does affect the max PL and the location estimate, and we recommend that users of Loki explore how their results vary with different bin widths.

  17. Search for Gravitational Waves from Intermediate Mass Binary Black Holes

    Science.gov (United States)

    Blackburn, L.; Camp, J. B.; Cannizzo, J.; Stroeer, A. S.

    2012-01-01

    We present the results of a weakly modeled burst search for gravitational waves from mergers of non-spinning intermediate mass black holes (IMBH) in the total mass range 100-450 solar Mass and with the component mass ratios between 1:1 and 4:1. The search was conducted on data collected by the LIGO and Virgo detectors between November of 2005 and October of 2007. No plausible signals were observed by the search which constrains the astrophysical rates of the IMBH mergers as a function of the component masses. In the most efficiently detected bin centered on 88 + 88 solar Mass , for non-spinning sources, the rate density upper limit is 0.13 per Mpc(exp 3) per Myr at the 90% confidence level.

  18. the Ĝ infrared search for extraterrestrial civilizations with large energy supplies. II. Framework, strategy, and first result

    International Nuclear Information System (INIS)

    Wright, J. T.; Griffith, R. L.; Sigurdsson, S.; Povich, M. S.; Mullan, B.

    2014-01-01

    We describe the framework and strategy of the Ĝ infrared search for extraterrestrial civilizations with large energy supplies, which will use the wide-field infrared surveys of WISE and Spitzer to search for these civilizations' waste heat. We develop a formalism for translating mid-infrared photometry into quantitative upper limits on extraterrestrial energy supplies. We discuss the likely sources of false positives, how dust can and will contaminate our search, and prospects for distinguishing dust from alien waste heat. We argue that galaxy-spanning civilizations may be easier to distinguish from natural sources than circumstellar civilizations (i.e., Dyson spheres), although GAIA will significantly improve our capability to identify the latter. We present a zeroth order null result of our search based on the WISE all-sky catalog: we show, for the first time, that Kardashev Type III civilizations (as Kardashev originally defined them) are very rare in the local universe. More sophisticated searches can extend our methodology to smaller waste heat luminosities, and potentially entirely rule out (or detect) both Kardashev Type III civilizations and new physics that allows for unlimited 'free' energy generation.

  19. the Ĝ infrared search for extraterrestrial civilizations with large energy supplies. II. Framework, strategy, and first result

    Energy Technology Data Exchange (ETDEWEB)

    Wright, J. T.; Griffith, R. L.; Sigurdsson, S. [Department of Astronomy and Astrophysics, 525 Davey Lab, The Pennsylvania State University, University Park, PA, 16802 (United States); Povich, M. S. [Department of Physics and Astronomy, California State Polytechnic University, Pomona, 3801 West Temple Avenue, Pomona, CA 91768 (United States); Mullan, B. [Blue Marble Space Institution of Science, P.O. Box 85561, Seattle, WA 98145-1561 (United States)

    2014-09-01

    We describe the framework and strategy of the Ĝ infrared search for extraterrestrial civilizations with large energy supplies, which will use the wide-field infrared surveys of WISE and Spitzer to search for these civilizations' waste heat. We develop a formalism for translating mid-infrared photometry into quantitative upper limits on extraterrestrial energy supplies. We discuss the likely sources of false positives, how dust can and will contaminate our search, and prospects for distinguishing dust from alien waste heat. We argue that galaxy-spanning civilizations may be easier to distinguish from natural sources than circumstellar civilizations (i.e., Dyson spheres), although GAIA will significantly improve our capability to identify the latter. We present a zeroth order null result of our search based on the WISE all-sky catalog: we show, for the first time, that Kardashev Type III civilizations (as Kardashev originally defined them) are very rare in the local universe. More sophisticated searches can extend our methodology to smaller waste heat luminosities, and potentially entirely rule out (or detect) both Kardashev Type III civilizations and new physics that allows for unlimited 'free' energy generation.

  20. The Ĝ Infrared Search for Extraterrestrial Civilizations with Large Energy Supplies. II. Framework, Strategy, and First Result

    Science.gov (United States)

    Wright, J. T.; Griffith, R. L.; Sigurdsson, S.; Povich, M. S.; Mullan, B.

    2014-09-01

    We describe the framework and strategy of the Ĝ infrared search for extraterrestrial civilizations with large energy supplies, which will use the wide-field infrared surveys of WISE and Spitzer to search for these civilizations' waste heat. We develop a formalism for translating mid-infrared photometry into quantitative upper limits on extraterrestrial energy supplies. We discuss the likely sources of false positives, how dust can and will contaminate our search, and prospects for distinguishing dust from alien waste heat. We argue that galaxy-spanning civilizations may be easier to distinguish from natural sources than circumstellar civilizations (i.e., Dyson spheres), although GAIA will significantly improve our capability to identify the latter. We present a zeroth order null result of our search based on the WISE all-sky catalog: we show, for the first time, that Kardashev Type III civilizations (as Kardashev originally defined them) are very rare in the local universe. More sophisticated searches can extend our methodology to smaller waste heat luminosities, and potentially entirely rule out (or detect) both Kardashev Type III civilizations and new physics that allows for unlimited "free" energy generation.

  1. Model-independent search for CP violation in D{sup 0}→K{sup −}K{sup +}π{sup −}π{sup +} and D{sup 0}→π{sup −}π{sup +}π{sup +}π{sup −} decays

    Energy Technology Data Exchange (ETDEWEB)

    Aaij, R. [Nikhef National Institute for Subatomic Physics, Amsterdam (Netherlands); Adeva, B. [Universidad de Santiago de Compostela, Santiago de Compostela (Spain); Adinolfi, M. [H.H. Wills Physics Laboratory, University of Bristol, Bristol (United Kingdom); Adrover, C. [CPPM, Aix-Marseille Université, CNRS/IN2P3, Marseille (France); Affolder, A. [Oliver Lodge Laboratory, University of Liverpool, Liverpool (United Kingdom); Ajaltouni, Z. [Clermont Université, Université Blaise Pascal, CNRS/IN2P3, LPC, Clermont-Ferrand (France); Albrecht, J. [Fakultät Physik, Technische Universit ät Dortmund, Dortmund (Germany); Alessio, F. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Alexander, M. [School of Physics and Astronomy, University of Glasgow, Glasgow (United Kingdom); Ali, S. [Nikhef National Institute for Subatomic Physics, Amsterdam (Netherlands); Alkhazov, G. [Petersburg Nuclear Physics Institute (PNPI), Gatchina (Russian Federation); Alvarez Cartelle, P. [Universidad de Santiago de Compostela, Santiago de Compostela (Spain); Alves, A.A. [Sezione INFN di Roma La Sapienza, Roma (Italy); European Organization for Nuclear Research (CERN), Geneva (Switzerland); Amato, S. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro (Brazil); Amerio, S. [Sezione INFN di Padova, Padova (Italy); Amhis, Y. [LAL, Université Paris-Sud, CNRS/IN2P3, Orsay (France); Anderlini, L. [Sezione INFN di Firenze, Firenze (Italy); Anderson, J. [Physik-Institut, Universität Zürich, Zürich (Switzerland); Andreassen, R. [University of Cincinnati, Cincinnati, OH (United States); Andrews, J.E. [University of Maryland, College Park, MD (United States); and others

    2013-11-04

    A search for CP violation in the phase-space structures of D{sup 0} and D{sup ¯0} decays to the final states K{sup −}K{sup +}π{sup −}π{sup +} and π{sup −}π{sup +}π{sup +}π{sup −} is presented. The search is carried out with a data set corresponding to an integrated luminosity of 1.0 fb{sup −1} collected in 2011 by the LHCb experiment in pp collisions at a centre-of-mass energy of 7 TeV. For the K{sup −}K{sup +}π{sup −}π{sup +} final state, the four-body phase space is divided into 32 bins, each bin with approximately 1800 decays. The p-value under the hypothesis of no CP violation is 9.1%, and in no bin is a CP asymmetry greater than 6.5% observed. The phase space of the π{sup −}π{sup +}π{sup +}π{sup −} final state is partitioned into 128 bins, each bin with approximately 2500 decays. The p-value under the hypothesis of no CP violation is 41%, and in no bin is a CP asymmetry greater than 5.5% observed. All results are consistent with the hypothesis of no CP violation at the current sensitivity.

  2. Global OpenSearch

    Science.gov (United States)

    Newman, D. J.; Mitchell, A. E.

    2015-12-01

    At AGU 2014, NASA EOSDIS demonstrated a case-study of an OpenSearch framework for Earth science data discovery. That framework leverages the IDN and CWIC OpenSearch API implementations to provide seamless discovery of data through the 'two-step' discovery process as outlined by the Federation for Earth Sciences (ESIP) OpenSearch Best Practices. But how would an Earth Scientist leverage this framework and what are the benefits? Using a client that understands the OpenSearch specification and, for further clarity, the various best practices and extensions, a scientist can discovery a plethora of data not normally accessible either by traditional methods (NASA Earth Data Search, Reverb, etc) or direct methods (going to the source of the data) We will demonstrate, via the CWICSmart web client, how an earth scientist can access regional data on a regional phenomena in a uniform and aggregated manner. We will demonstrate how an earth scientist can 'globalize' their discovery. You want to find local data on 'sea surface temperature of the Indian Ocean'? We can help you with that. 'European meteorological data'? Yes. 'Brazilian rainforest satellite imagery'? That too. CWIC allows you to get earth science data in a uniform fashion from a large number of disparate, world-wide agencies. This is what we mean by Global OpenSearch.

  3. ANALISIS TINGKAT OPTIMASI ALGORITMA GENETIKA DALAM HUKUM KETETAPAN HARDY-WEINBERG PADA BIN PACKING PROBLEM

    Directory of Open Access Journals (Sweden)

    Terry Noviar Panggabean

    2016-08-01

    Full Text Available Abstrak—Karna representasi abstrak dari beberapa sistem pengambilan keputusan yang nyata dalam kehidupan sehari hari membuat masalah optimasi kombinatorial umumnya sangat sulit untuk dipecahkan. Bin packing problem ialah solusi terbaik dalam mengatasi masalah optimasi kombinatorial, yang digunakan untuk mencari sebuah objek secara optimal dari sekelompok himpunan objek yang berhingga. Serangkaian pendekatan hybrid telah dikembangkan dalam hal ini untuk memecahkan masalah Bin Packing. Metaheuristik adalah salah satu pendekatan tingkat tinggi dalam memandu dalam memodifikasi beberapa metode heuristik lainnya untuk mencari tingkat optimasi yang lebih baik. Genetic Algorithm atau Algoritma Genetika juga merupakan metode metaheuristik yang digunakan untuk menyelesaikan berbagai masalah dalam hal peningkatan optimasi. Dalam algoritma genetika terdapat bermacam-macam varian. Dalam penelitian dipaparkan mengenai taksonomi dari algoritma genetika parallel (Parallel Genetic Algorithm yang memiliki kemampuan yang lebih baik dari algoritma genetika konvensional dalam hal kinerja dan skalabilitasnya. Tetapi algoritma genetika paralel ini hanya cocok untuk permasalahan jaringan komputer heterogen dan sistem terdistribusi. Berdasarkan penelitian yang sudah pernah dilakukan sebelumnya dan dari uraian diatas maka penulis tertarik untuk melakukan penelitian bagaimana menerapkan hukum ketetapan Hardy-Weinberg dari bidang biologi kedalam algoritma genetika melakukan analisis tingkat optimasi terhadap Bin Packing Problem..   Keywords— Genetic Algortihm, Hardy-Weinberg, Bin Packing Problem.

  4. Rumsfeld: Osama bin Ladenil polnud sidemeid Saddamiga / Heiki Suurkask

    Index Scriptorium Estoniae

    Suurkask, Heiki, 1972-

    2004-01-01

    Valeks on osutunud väide, et Saddam Husseini ja bin Ladeni vahel oli tihe koostöö. Autori sõnul uurisid Richard Cheney, Donald Rumsfeld ja USA praegune asekaitseminister Paul Wolfowitz juba 1990-ndate keskel võimalusi uueks sõjaks Iraagi vastu. Lisa: Bremer süüdistab Valget Maja

  5. Comparability of outcome frameworks in medical education: Implications for framework development.

    Science.gov (United States)

    Hautz, Stefanie C; Hautz, Wolf E; Feufel, Markus A; Spies, Claudia D

    2015-01-01

    Given the increasing mobility of medical students and practitioners, there is a growing need for harmonization of medical education and qualifications. Although several initiatives have sought to compare national outcome frameworks, this task has proven a challenge. Drawing on an analysis of existing outcome frameworks, we identify factors that hinder comparability and suggest ways of facilitating comparability during framework development and revisions. We searched MedLine, EmBase and the Internet for outcome frameworks in medical education published by national or governmental organizations. We analyzed these frameworks for differences and similarities that influence comparability. Of 1816 search results, 13 outcome frameworks met our inclusion criteria. These frameworks differ in five core features: history and origins, formal structure, medical education system, target audience and key terms. Many frameworks reference other frameworks without acknowledging these differences. Importantly, the level of detail of the outcomes specified differs both within and between frameworks. The differences identified explain some of the challenges involved in comparing outcome frameworks and medical qualifications. We propose a two-level model distinguishing between "core" competencies and culture-specific "secondary" competencies. This approach could strike a balance between local specifics and cross-national comparability of outcome frameworks and medical education.

  6. User's manual for BINIAC: A computer code to translate APET bins

    International Nuclear Information System (INIS)

    Gough, S.T.

    1994-03-01

    This report serves as the user's manual for the FORTRAN code BINIAC. BINIAC is a utility code designed to format the output from the Defense Waste Processing Facility (DWPF) Accident Progression Event Tree (APET) methodology. BINIAC inputs the accident progression bins from the APET methodology, converts the frequency from occurrences per hour to occurrences per year, sorts the progression bins, and converts the individual dimension character codes into facility attributes. Without the use of BINIAC, this process would be done manually at great time expense. BINIAC was written under the quality assurance control of IQ34 QAP IV-1, revision 0, section 4.1.4. Configuration control is established through the use of a proprietor and a cognizant users list

  7. SeaWiFS technical report series. Volume 32: Level-3 SeaWiFS data products. Spatial and temporal binning algorithms

    Science.gov (United States)

    Hooker, Stanford B. (Editor); Firestone, Elaine R. (Editor); Acker, James G. (Editor); Campbell, Janet W.; Blaisdell, John M.; Darzi, Michael

    1995-01-01

    The level-3 data products from the Sea-viewing Wide Field-of-view Sensor (SeaWiFS) are statistical data sets derived from level-2 data. Each data set will be based on a fixed global grid of equal-area bins that are approximately 9 x 9 sq km. Statistics available for each bin include the sum and sum of squares of the natural logarithm of derived level-2 geophysical variables where sums are accumulated over a binning period. Operationally, products with binning periods of 1 day, 8 days, 1 month, and 1 year will be produced and archived. From these accumulated values and for each bin, estimates of the mean, standard deviation, median, and mode may be derived for each geophysical variable. This report contains two major parts: the first (Section 2) is intended as a users' guide for level-3 SeaWiFS data products. It contains an overview of level-0 to level-3 data processing, a discussion of important statistical considerations when using level-3 data, and details of how to use the level-3 data. The second part (Section 3) presents a comparative statistical study of several binning algorithms based on CZCS and moored fluorometer data. The operational binning algorithms were selected based on the results of this study.

  8. Augmented neural networks and problem structure-based heuristics for the bin-packing problem

    Science.gov (United States)

    Kasap, Nihat; Agarwal, Anurag

    2012-08-01

    In this article, we report on a research project where we applied augmented-neural-networks (AugNNs) approach for solving the classical bin-packing problem (BPP). AugNN is a metaheuristic that combines a priority rule heuristic with the iterative search approach of neural networks to generate good solutions fast. This is the first time this approach has been applied to the BPP. We also propose a decomposition approach for solving harder BPP, in which subproblems are solved using a combination of AugNN approach and heuristics that exploit the problem structure. We discuss the characteristics of problems on which such problem structure-based heuristics could be applied. We empirically show the effectiveness of the AugNN and the decomposition approach on many benchmark problems in the literature. For the 1210 benchmark problems tested, 917 problems were solved to optimality and the average gap between the obtained solution and the upper bound for all the problems was reduced to under 0.66% and computation time averaged below 33 s per problem. We also discuss the computational complexity of our approach.

  9. Application of Genetic Algorithm for the Bin Packing Problem with a New Representation Scheme

    Directory of Open Access Journals (Sweden)

    N. Mohamadi

    2010-10-01

    Full Text Available The Bin Packing Problem (BPP is to find the minimum number of binsneeded to pack a given set of objects of known sizes so that they donot exceed the capacity of each bin. This problem is known to beNP-Hard [5]; hence many heuristic procedures for its solution havebeen suggested. In this paper we propose a new representation schemeand solve the problem by a Genetic Algorithm. Limited computationalresults show the efficiency of this scheme.

  10. Test Plan: WIPP bin-scale CH TRU waste tests

    International Nuclear Information System (INIS)

    Molecke, M.A.

    1990-08-01

    This WIPP Bin-Scale CH TRU Waste Test program described herein will provide relevant composition and kinetic rate data on gas generation and consumption resulting from TRU waste degradation, as impacted by synergistic interactions due to multiple degradation modes, waste form preparation, long-term repository environmental effects, engineered barrier materials, and, possibly, engineered modifications to be developed. Similar data on waste-brine leachate compositions and potentially hazardous volatile organic compounds released by the wastes will also be provided. The quantitative data output from these tests and associated technical expertise are required by the WIPP Performance Assessment (PA) program studies, and for the scientific benefit of the overall WIPP project. This Test Plan describes the necessary scientific and technical aspects, justifications, and rational for successfully initiating and conducting the WIPP Bin-Scale CH TRU Waste Test program. This Test Plan is the controlling scientific design definition and overall requirements document for this WIPP in situ test, as defined by Sandia National Laboratories (SNL), scientific advisor to the US Department of Energy, WIPP Project Office (DOE/WPO). 55 refs., 16 figs., 19 tabs

  11. Osama bin Laden - elus või siiski ammu surnud? / Aadu Hiietamm

    Index Scriptorium Estoniae

    Hiietamm, Aadu, 1954-

    2009-01-01

    USA on terrorivõrgustiku al Qaeda juhti Osama bin Ladenit jahitud juba kaheksa aastat, kuid tulemusteta. Vandenõuteoreetikute arvates on ta ammu surnud, kuid USA Luure Keskagentuuri juhi arvates varjab ta end Pakistanis

  12. Moleculo Long-Read Sequencing Facilitates Assembly and Genomic Binning from Complex Soil Metagenomes

    Energy Technology Data Exchange (ETDEWEB)

    White, Richard Allen; Bottos, Eric M.; Roy Chowdhury, Taniya; Zucker, Jeremy D.; Brislawn, Colin J.; Nicora, Carrie D.; Fansler, Sarah J.; Glaesemann, Kurt R.; Glass, Kevin; Jansson, Janet K.; Langille, Morgan

    2016-06-28

    ABSTRACT

    Soil metagenomics has been touted as the “grand challenge” for metagenomics, as the high microbial diversity and spatial heterogeneity of soils make them unamenable to current assembly platforms. Here, we aimed to improve soil metagenomic sequence assembly by applying the Moleculo synthetic long-read sequencing technology. In total, we obtained 267 Gbp of raw sequence data from a native prairie soil; these data included 109.7 Gbp of short-read data (~100 bp) from the Joint Genome Institute (JGI), an additional 87.7 Gbp of rapid-mode read data (~250 bp), plus 69.6 Gbp (>1.5 kbp) from Moleculo sequencing. The Moleculo data alone yielded over 5,600 reads of >10 kbp in length, and over 95% of the unassembled reads mapped to contigs of >1.5 kbp. Hybrid assembly of all data resulted in more than 10,000 contigs over 10 kbp in length. We mapped three replicate metatranscriptomes derived from the same parent soil to the Moleculo subassembly and found that 95% of the predicted genes, based on their assignments to Enzyme Commission (EC) numbers, were expressed. The Moleculo subassembly also enabled binning of >100 microbial genome bins. We obtained via direct binning the first complete genome, that of “CandidatusPseudomonas sp. strain JKJ-1” from a native soil metagenome. By mapping metatranscriptome sequence reads back to the bins, we found that several bins corresponding to low-relative-abundanceAcidobacteriawere highly transcriptionally active, whereas bins corresponding to high-relative-abundanceVerrucomicrobiawere not. These results demonstrate that Moleculo sequencing provides a significant advance for resolving complex soil microbial communities.

    IMPORTANCESoil microorganisms carry out key processes for life on our planet, including cycling of carbon and other nutrients and supporting growth of plants. However, there is poor molecular-level understanding of their

  13. Search Advertising

    OpenAIRE

    Cornière (de), Alexandre

    2016-01-01

    Search engines enable advertisers to target consumers based on the query they have entered. In a framework with horizontal product differentiation, imperfect product information and in which consumers incur search costs, I study a game in which advertisers have to choose a price and a set of relevant keywords. The targeting mechanism brings about three kinds of efficiency gains, namely lower search costs, better matching, and more intense product market price-competition. A monopolistic searc...

  14. Osama bin Ladeni tapmine toonuks tuumapõrgu / Kaivo Kopli

    Index Scriptorium Estoniae

    Kopli, Kaivo

    2011-01-01

    Wikileaksi kaudu on avalikustatud märkmeid Guantánamo vangide ülekuulamistest. Ühe al-Qaida komandöri väitel on terroristidel kuhugi Euroopasse peidetud tuumapomm, mis oleks pandud plahvatama, kui Osama bin Laden oleks vangistatud või tapetud. Selgub, et Guantanamos oli umbes 150 kinnipeetut täiesti süütud

  15. A FRAMEWORK FOR INTERPRETING FAST RADIO TRANSIENTS SEARCH EXPERIMENTS: APPLICATION TO THE V-FASTR EXPERIMENT

    International Nuclear Information System (INIS)

    Trott, Cathryn M.; Tingay, Steven J.; Wayth, Randall B.; Macquart, Jean-Pierre R.; Palaniswamy, Divya; Thompson, David R.; Wagstaff, Kiri L.; Majid, Walid A.; Burke-Spolaor, Sarah; Deller, Adam T.; Brisken, Walter F.

    2013-01-01

    We define a framework for determining constraints on the detection rate of fast transient events from a population of underlying sources, with a view to incorporate beam shape, frequency effects, scattering effects, and detection efficiency into the metric. We then demonstrate a method for combining independent data sets into a single event rate constraint diagram, using a probabilistic approach to the limits on parameter space. We apply this new framework to present the latest results from the V-FASTR experiment, a commensal fast transients search using the Very Long Baseline Array (VLBA). In the 20 cm band, V-FASTR now has the ability to probe the regions of parameter space of importance for the observed Lorimer and Keane fast radio transient candidates by combining the information from observations with differing bandwidths, and properly accounting for the source dispersion measure, VLBA antenna beam shape, experiment time sampling, and stochastic nature of events. We then apply the framework to combine the results of the V-FASTR and Allen Telescope Array Fly's Eye experiments, demonstrating their complementarity. Expectations for fast transients experiments for the SKA Phase I dish array are then computed, and the impact of large differential bandwidths is discussed.

  16. Comparing Online Algorithms for Bin Packing Problems

    DEFF Research Database (Denmark)

    Epstein, Leah; Favrholdt, Lene Monrad; Kohrt, Jens Svalgaard

    2012-01-01

    The relative worst-order ratio is a measure of the quality of online algorithms. In contrast to the competitive ratio, this measure compares two online algorithms directly instead of using an intermediate comparison with an optimal offline algorithm. In this paper, we apply the relative worst-ord......-order ratio to online algorithms for several common variants of the bin packing problem. We mainly consider pairs of algorithms that are not distinguished by the competitive ratio and show that the relative worst-order ratio prefers the intuitively better algorithm of each pair....

  17. A Secured Cognitive Agent based Multi-strategic Intelligent Search System

    Directory of Open Access Journals (Sweden)

    Neha Gulati

    2018-04-01

    Full Text Available Search Engine (SE is the most preferred information retrieval tool ubiquitously used. In spite of vast scale involvement of users in SE’s, their limited capabilities to understand the user/searcher context and emotions places high cognitive, perceptual and learning load on the user to maintain the search momentum. In this regard, the present work discusses a Cognitive Agent (CA based approach to support the user in Web-based search process. The work suggests a framework called Secured Cognitive Agent based Multi-strategic Intelligent Search System (CAbMsISS to assist the user in search process. It helps to reduce the contextual and emotional mismatch between the SE’s and user. After implementation of the proposed framework, performance analysis shows that CAbMsISS framework improves Query Retrieval Time (QRT and effectiveness for retrieving relevant results as compared to Present Search Engine (PSE. Supplementary to this, it also provides search suggestions when user accesses a resource previously tagged with negative emotions. Overall, the goal of the system is to enhance the search experience for keeping the user motivated. The framework provides suggestions through the search log that tracks the queries searched, resources accessed and emotions experienced during the search. The implemented framework also considers user security. Keywords: BDI model, Cognitive Agent, Emotion, Information retrieval, Intelligent search, Search Engine

  18. LHCb: Search for CP violation in $D^+ \\to K^-K^+\\pi^+$ decays at LHCb

    CERN Multimedia

    Gordon, Hamish

    2012-01-01

    A model-independent search for direct CP violation in the Cabibbo suppressed decay $D^+ \\to K^-K^+\\pi^+$ in a sample of approximately 370,000 decays is described. The normalized Dalitz plot distributions for $D^+$ and $D^-$ are compared using four different binning schemes that are sensitive to different manifestations of CP violation. No evidence for CP asymmetry is found.

  19. PhyloPythiaS+: a self-training method for the rapid reconstruction of low-ranking taxonomic bins from metagenomes.

    Science.gov (United States)

    Gregor, Ivan; Dröge, Johannes; Schirmer, Melanie; Quince, Christopher; McHardy, Alice C

    2016-01-01

    Background. Metagenomics is an approach for characterizing environmental microbial communities in situ, it allows their functional and taxonomic characterization and to recover sequences from uncultured taxa. This is often achieved by a combination of sequence assembly and binning, where sequences are grouped into 'bins' representing taxa of the underlying microbial community. Assignment to low-ranking taxonomic bins is an important challenge for binning methods as is scalability to Gb-sized datasets generated with deep sequencing techniques. One of the best available methods for species bins recovery from deep-branching phyla is the expert-trained PhyloPythiaS package, where a human expert decides on the taxa to incorporate in the model and identifies 'training' sequences based on marker genes directly from the sample. Due to the manual effort involved, this approach does not scale to multiple metagenome samples and requires substantial expertise, which researchers who are new to the area do not have. Results. We have developed PhyloPythiaS+, a successor to our PhyloPythia(S) software. The new (+) component performs the work previously done by the human expert. PhyloPythiaS+ also includes a new k-mer counting algorithm, which accelerated the simultaneous counting of 4-6-mers used for taxonomic binning 100-fold and reduced the overall execution time of the software by a factor of three. Our software allows to analyze Gb-sized metagenomes with inexpensive hardware, and to recover species or genera-level bins with low error rates in a fully automated fashion. PhyloPythiaS+ was compared to MEGAN, taxator-tk, Kraken and the generic PhyloPythiaS model. The results showed that PhyloPythiaS+ performs especially well for samples originating from novel environments in comparison to the other methods. Availability. PhyloPythiaS+ in a virtual machine is available for installation under Windows, Unix systems or OS X on: https://github.com/algbioi/ppsp/wiki.

  20. Independent technical review of the Bin and Alcove test programs at the Waste Isolation Pilot Plant

    International Nuclear Information System (INIS)

    1993-12-01

    This Independent Technical Review (ITR) assessed the need for and technical validity of the proposed Bin and Alcove test programs using TRU-waste at the WIPP site. The ITR Team recommends that the planned Bin and Alcove tests be abandoned, and that new activities be initiated in support of the WIPP regulatory compliance processes. Recommendations in this report offer an alternate path for expeditiously attaining disposal certification and permitting

  1. Development of a new bin filler for apple harvesting and infield sorting with a review of existing technologies

    Science.gov (United States)

    The bin filler, which receives apples from the sorting system and then places them in the bin evenly without causing bruise damage, plays a critical role for the self-propelled apple harvest and infield sorting (HIS) machine that is being developed in our laboratory. Two major technical challenges ...

  2. Numerical simulation of turbulent flows past the RoBin helicopter with a four-bladed rotor

    Energy Technology Data Exchange (ETDEWEB)

    Xu, H.; Mamou, M.; Khalid, M. [National Research Council, Inst. for Aerospace Research, Ottawa, Ontario (Canada)]. E-mail: Hongyi.Xu@nrc.ca

    2003-07-01

    The current paper presents a turbulent flow simulation study past a generic helicopter RoBin with a four-bladed rotor using the Chimera moving grid approach. The aerodynamic performance of the rotor blades and their interactions with the RoBin fuselage are investigated using the k - {omega} SST turbulence model contained in the WIND code. The rotor is configured as a Chimera moving grid in a quasisteady flow field. The rotor blades are rectangular, untapered, linearly twisted and are made from NACA 0012 airfoil profile. The blade motion (rotation and cyclic pitching) schedule is specified in the NASA wind tunnel testing of a generic helicopter RoBin. The aerodynamic radial load distributions in the rotor plane are generated by integrating the pressure on each blade surfaces along the blade chordwise direction. The rotor flow interacts strongly with the flow coming off from the fuselage and thus has a significant impact on helicopter aerodynamic performance. (author)

  3. Improving a Spectral Bin Microphysical Scheme Using TRMM Satellite Observations

    Science.gov (United States)

    Li, Xiaowen; Tao, Wei-Kuo; Matsui, Toshihisa; Liu, Chuntao; Masunaga, Hirohiko

    2010-01-01

    Comparisons between cloud model simulations and observations are crucial in validating model performance and improving physical processes represented in the mod Tel.hese modeled physical processes are idealized representations and almost always have large rooms for improvements. In this study, we use data from two different sensors onboard TRMM (Tropical Rainfall Measurement Mission) satellite to improve the microphysical scheme in the Goddard Cumulus Ensemble (GCE) model. TRMM observed mature-stage squall lines during late spring, early summer in central US over a 9-year period are compiled and compared with a case simulation by GCE model. A unique aspect of the GCE model is that it has a state-of-the-art spectral bin microphysical scheme, which uses 33 different bins to represent particle size distribution of each of the seven hydrometeor species. A forward radiative transfer model calculates TRMM Precipitation Radar (PR) reflectivity and TRMM Microwave Imager (TMI) 85 GHz brightness temperatures from simulated particle size distributions. Comparisons between model outputs and observations reveal that the model overestimates sizes of snow/aggregates in the stratiform region of the squall line. After adjusting temperature-dependent collection coefficients among ice-phase particles, PR comparisons become good while TMI comparisons worsen. Further investigations show that the partitioning between graupel (a high-density form of aggregate), and snow (a low-density form of aggregate) needs to be adjusted in order to have good comparisons in both PR reflectivity and TMI brightness temperature. This study shows that long-term satellite observations, especially those with multiple sensors, can be very useful in constraining model microphysics. It is also the first study in validating and improving a sophisticated spectral bin microphysical scheme according to long-term satellite observations.

  4. Solar-Powered Compaction Garbage Bins in Public Areas: A Preliminary Economic and Environmental Evaluation

    Directory of Open Access Journals (Sweden)

    Long Duc Nghiem

    2010-02-01

    Full Text Available An excel-based model was developed to evaluate economic and environmental benefits of the solar-powered compaction garbage bins in public areas in Australia. Input data were collected from Brisbane and Wollongong City councils, and Sydney Olympic Park. The results demonstrate that solar-powered compaction garbage bins would provide environmental benefits in all scenarios. However, results of the economic analysis of the three studied areas varied significantly. The unique situation of Sydney Olympic Park made implementation in that facility particularly appealing. A lower monthly rental cost is needed for the implementation of this novel waste management practice.

  5. A framework for intelligent data acquisition and real-time database searching for shotgun proteomics.

    Science.gov (United States)

    Graumann, Johannes; Scheltema, Richard A; Zhang, Yong; Cox, Jürgen; Mann, Matthias

    2012-03-01

    In the analysis of complex peptide mixtures by MS-based proteomics, many more peptides elute at any given time than can be identified and quantified by the mass spectrometer. This makes it desirable to optimally allocate peptide sequencing and narrow mass range quantification events. In computer science, intelligent agents are frequently used to make autonomous decisions in complex environments. Here we develop and describe a framework for intelligent data acquisition and real-time database searching and showcase selected examples. The intelligent agent is implemented in the MaxQuant computational proteomics environment, termed MaxQuant Real-Time. It analyzes data as it is acquired on the mass spectrometer, constructs isotope patterns and SILAC pair information as well as controls MS and tandem MS events based on real-time and prior MS data or external knowledge. Re-implementing a top10 method in the intelligent agent yields similar performance to the data dependent methods running on the mass spectrometer itself. We demonstrate the capabilities of MaxQuant Real-Time by creating a real-time search engine capable of identifying peptides "on-the-fly" within 30 ms, well within the time constraints of a shotgun fragmentation "topN" method. The agent can focus sequencing events onto peptides of specific interest, such as those originating from a specific gene ontology (GO) term, or peptides that are likely modified versions of already identified peptides. Finally, we demonstrate enhanced quantification of SILAC pairs whose ratios were poorly defined in survey spectra. MaxQuant Real-Time is flexible and can be applied to a large number of scenarios that would benefit from intelligent, directed data acquisition. Our framework should be especially useful for new instrument types, such as the quadrupole-Orbitrap, that are currently becoming available.

  6. Odor volatiles associated with microflora in damp ventilated and non-ventilated bin-stored bulk wheat.

    Science.gov (United States)

    Tuma, D; Sinha, R N; Muir, W E; Abramson, D

    1989-05-01

    Western hard red spring wheat, stored at 20 and 25% moisture contents for 10 months during 1985-86, was monitored for biotic and abiotic variables in 10 unheated bins in Winnipeg, Manitoba. The major odor volatiles identified were 3-methyl-1-butanol, 3-octanone and 1-octen-3-ol. The production of these volatiles was associated and correlated with microfloral infection. Ventilation, used for cooling and drying of grain, disrupted microfloral growth patterns and production of volatiles. The highest levels of 3-methyl-1-butanol occurred in 25% moisture content wheat infected with bacteria, Penicillium spp. and Fusarium spp. In non-ventilated (control) bins with 20% moisture content wheat, 3-methyl-1-butanol was correlated with infection by members of the Aspergillus glaucus group and bacteria. In control bins, 1-octen-3-ol production was correlated with infection of wheat of both moisture contents by Penicillium spp. The fungal species, isolated from damp bin-stored wheat and tested for production of odor volatiles on wheat substrate, included Alternaria alternata (Fr.) Keissler, Aspergillus repens (Corda) Saccardo, A. flavus Link ex Fries, A. versicolor (Vuill.) Tiraboschi, Penicillium chrysogenum Thom, P. cyclopium Westling, Fusarium moniliforme Sheldon, F. semitectum (Cooke) Sacc. In the laboratory, fungus-inoculated wheat produced 3-methyl-1-butanol; 3-octanone and 1-octen-3-ol were also produced, but less frequently. Two unidentified bacterial species isolated from damp wheat and inoculated on agar produced 3-methyl-1-butanol.

  7. The effect of stocking density and bin feeder space on performance ...

    African Journals Online (AJOL)

    The effect of stocking density and bin feeder space on performance in pigs. G.A. Lavers, N.S. Ferguson. Abstract. (South African J of Animal Science, 2000, 30, Supplement 1: 70-71). Full Text: EMAIL FREE FULL TEXT EMAIL FREE FULL TEXT · DOWNLOAD FULL TEXT DOWNLOAD FULL TEXT.

  8. Time-bin quantum RAM

    Science.gov (United States)

    Moiseev, E. S.; Moiseev, S. A.

    2016-11-01

    We have proposed a compact scheme of quantum random access memory (qRAM) based on the impedance matched multi-qubit photon echo quantum memory incorporated with the control four-level atom in two coupled QED cavities. A set of matching conditions for basic physical parameters of the qRAM scheme that provides an efficient quantum control of the fast single photon storage and readout has been found. In particular, it has been discovered that the efficient qRAM operations are determined by the specific properties of the excited photonic molecule coupling the two QED cavities. Herein, the maximal efficiency of the qRAM is realized when the cooperativity parameter of the photonic molecule equals to unity that can be experimentally achievable. We have also elaborated upon the new quantum address scheme where the multi-time-bin photon state is used for the control of the four-level atom during the readout of the photonic qubits from the quantum memory. The scheme reduces the required number of logical elements to one. Experimental implementation by means of current quantum technologies in the optical and microwave domains is also discussed.

  9. Search for CP violation in $D^{+} \\to K^{-}K^{+}\\pi^{+}$ decays

    CERN Document Server

    Aaij, R.; Adinolfi, M.; Adrover, C.; Affolder, A.; Ajaltouni, Z.; Albrecht, J.; Alessio, F.; Alexander, M.; Alkhazov, G.; Alvarez Cartelle, P.; Alves, A.A.; Amato, S.; Amhis, Y.; Anderson, J.; Appleby, R.B.; Aquines Gutierrez, O.; Archilli, F.; Arrabito, L.; Artamonov, A.; Artuso, M.; Aslanides, E.; Auriemma, G.; Bachmann, S.; Back, J.J.; Bailey, D.S.; Balagura, V.; Baldini, W.; Barlow, R.J.; Barschel, C.; Barsuk, S.; Barter, W.; Bates, A.; Bauer, C.; Bauer, Th.; Bay, A.; Bediaga, I.; Belous, K.; Belyaev, I.; Ben-Haim, E.; Benayoun, M.; Bencivenni, G.; Benson, S.; Benton, J.; Bernet, R.; Bettler, M.O.; van Beuzekom, M.; Bien, A.; Bifani, S.; Bizzeti, A.; Bjornstad, P.M.; Blake, T.; Blanc, F.; Blanks, C.; Blouw, J.; Blusk, S.; Bobrov, A.; Bocci, V.; Bondar, A.; Bondar, N.; Bonivento, W.; Borghi, S.; Borgia, A.; Bowcock, T.J.V.; Bozzi, C.; Brambach, T.; van den Brand, J.; Bressieux, J.; Brett, D.; Brisbane, S.; Britsch, M.; Britton, T.; Brook, N.H.; Brown, H.; Buchler-Germann, A.; Burducea, I.; Bursche, A.; Buytaert, J.; Cadeddu, S.; Caicedo Carvajal, J.M.; Callot, O.; Calvi, M.; Calvo Gomez, M.; Camboni, A.; Campana, P.; Carbone, A.; Carboni, G.; Cardinale, R.; Cardini, A.; Carson, L.; Carvalho Akiba, K.; Casse, G.; Cattaneo, M.; Charles, M.; Charpentier, Ph.; Chiapolini, N.; Ciba, K.; Cid Vidal, X.; Ciezarek, G.; Clarke, P.E.L.; Clemencic, M.; Cliff, H.V.; Closier, J.; Coca, C.; Coco, V.; Cogan, J.; Collins, P.; Constantin, F.; Conti, G.; Contu, A.; Cook, A.; Coombes, M.; Corti, G.; Cowan, G.A.; Currie, R.; D'Almagne, B.; D'Ambrosio, C.; David, P.; De Bonis, I.; De Capua, S.; De Cian, M.; De Lorenzi, F.; De Miranda, J.M.; De Paula, L.; De Simone, P.; Decamp, D.; Deckenhoff, M.; Degaudenzi, H.; Deissenroth, M.; Del Buono, L.; Deplano, C.; Deschamps, O.; Dettori, F.; Dickens, J.; Dijkstra, H.; Diniz Batista, P.; Donleavy, S.; Dordei, F.; Dosil Suarez, A.; Dossett, D.; Dovbnya, A.; Dupertuis, F.; Dzhelyadin, R.; Eames, C.; Easo, S.; Egede, U.; Egorychev, V.; Eidelman, S.; van Eijk, D.; Eisele, F.; Eisenhardt, S.; Ekelhof, R.; Eklund, L.; Elsasser, Ch.; d'Enterria, D.G.; Esperante Pereira, D.; Esteve, L.; Falabella, A.; Fanchini, E.; Farber, C.; Fardell, G.; Farinelli, C.; Farry, S.; Fave, V.; Fernandez Albor, V.; Ferro-Luzzi, M.; Filippov, S.; Fitzpatrick, C.; Fontana, M.; Fontanelli, F.; Forty, R.; Frank, M.; Frei, C.; Frosini, M.; Furcas, S.; Gallas Torreira, A.; Galli, D.; Gandelman, M.; Gandini, P.; Gao, Y.; Garnier, J-C.; Garofoli, J.; Garra Tico, J.; Garrido, L.; Gaspar, C.; Gauvin, N.; Gersabeck, M.; Gershon, T.; Ghez, Ph.; Gibson, V.; Gligorov, V.V.; Gobel, C.; Golubkov, D.; Golutvin, A.; Gomes, A.; Gordon, H.; Grabalosa Gandara, M.; Graciani Diaz, R.; Granado Cardoso, L.A.; Grauges, E.; Graziani, G.; Grecu, A.; Gregson, S.; Gui, B.; Gushchin, E.; Guz, Yu.; Gys, T.; Haefeli, G.; Haen, C.; Haines, S.C.; Hampson, T.; Hansmann-Menzemer, S.; Harji, R.; Harnew, N.; Harrison, J.; Harrison, P.F.; He, J.; Heijne, V.; Hennessy, K.; Henrard, P.; Hernando Morata, J.A.; van Herwijnen, E.; Hicks, E.; Hofmann, W.; Holubyev, K.; Hopchev, P.; Hulsbergen, W.; Hunt, P.; Huse, T.; Huston, R.S.; Hutchcroft, D.; Hynds, D.; Iakovenko, V.; Ilten, P.; Imong, J.; Jacobsson, R.; Jaeger, A.; Jahjah Hussein, M.; Jans, E.; Jansen, F.; Jaton, P.; Jean-Marie, B.; Jing, F.; John, M.; Johnson, D.; Jones, C.R.; Jost, B.; Kandybei, S.; Karacson, M.; Karbach, T.M.; Keaveney, J.; Kerzel, U.; Ketel, T.; Keune, A.; Khanji, B.; Kim, Y.M.; Knecht, M.; Koblitz, S.; Koppenburg, P.; Kozlinskiy, A.; Kravchuk, L.; Kreplin, K.; Kreps, M.; Krocker, G.; Krokovny, P.; Kruse, F.; Kruzelecki, K.; Kucharczyk, M.; Kukulak, S.; Kumar, R.; Kvaratskheliya, T.; La Thi, V.N.; Lacarrere, D.; Lafferty, G.; Lai, A.; Lambert, D.; Lambert, R.W.; Lanciotti, E.; Lanfranchi, G.; Langenbruch, C.; Latham, T.; Le Gac, R.; van Leerdam, J.; Lees, J.P.; Lefevre, R.; Leflat, A.; Lefrancois, J.; Leroy, O.; Lesiak, T.; Li, L.; Li Gioi, L.; Lieng, M.; Liles, M.; Lindner, R.; Linn, C.; Liu, B.; Liu, G.; Lopes, J.H.; Lopez Asamar, E.; Lopez-March, N.; Luisier, J.; Machefert, F.; Machikhiliyan, I.V.; Maciuc, F.; Maev, O.; Magnin, J.; Malde, S.; Mamunur, R.M.D.; Manca, G.; Mancinelli, G.; Mangiafave, N.; Marconi, U.; Marki, R.; Marks, J.; Martellotti, G.; Martens, A.; Martin, L.; Martin Sanchez, A.; Martinez Santos, D.; Martins Tostes, D.; Massafferri, A.; Mathe, Z.; Matteuzzi, C.; Matveev, M.; Maurice, E.; Maynard, B.; Mazurov, A.; McGregor, G.; McNulty, R.; Mclean, C.; Meissner, M.; Merk, M.; Merkel, J.; Messi, R.; Miglioranzi, S.; Milanes, D.A.; Minard, M.N.; Molina Rodriguez, J.; Monteil, S.; Moran, D.; Morawski, P.; Mountain, R.; Mous, I.; Muheim, F.; Muller, K.; Muresan, R.; Muryn, B.; Musy, M.; Mylroie-Smith, J.; Naik, P.; Nakada, T.; Nandakumar, R.; Nardulli, J.; Nasteva, I.; Nedos, M.; Needham, M.; Neufeld, N.; Nguyen-Mau, C.; Nicol, M.; Nies, S.; Niess, V.; Nikitin, N.; Oblakowska-Mucha, A.; Obraztsov, V.; Oggero, S.; Ogilvy, S.; Okhrimenko, O.; Oldeman, R.; Orlandea, M.; Otalora Goicochea, J.M.; Owen, P.; Pal, B.; Palacios, J.; Palutan, M.; Panman, J.; Papanestis, A.; Pappagallo, M.; Parkes, C.; Parkinson, C.J.; Passaleva, G.; Patel, G.D.; Patel, M.; Paterson, S.K.; Patrick, G.N.; Patrignani, C.; Pavel-Nicorescu, C.; Pazos Alvarez, A.; Pellegrino, A.; Penso, G.; Pepe Altarelli, M.; Perazzini, S.; Perego, D.L.; Perez Trigo, E.; Perez-Calero Yzquierdo, A.; Perret, P.; Perrin-Terrin, M.; Pessina, G.; Petrella, A.; Petrolini, A.; Pie Valls, B.; Pietrzyk, B.; Pilar, T.; Pinci, D.; Plackett, R.; Playfer, S.; Plo Casasus, M.; Polok, G.; Poluektov, A.; Polycarpo, E.; Popov, D.; Popovici, B.; Potterat, C.; Powell, A.; du Pree, T.; Prisciandaro, J.; Pugatch, V.; Puig Navarro, A.; Qian, W.; Rademacker, J.H.; Rakotomiaramanana, B.; Rangel, M.S.; Raniuk, I.; Raven, G.; Redford, S.; Reid, M.M.; dos Reis, A.C.; Ricciardi, S.; Rinnert, K.; Roa Romero, D.A.; Robbe, P.; Rodrigues, E.; Rodrigues, F.; Rodriguez Perez, P.; Rogers, G.J.; Roiser, S.; Romanovsky, V.; Rouvinet, J.; Ruf, T.; Ruiz, H.; Sabatino, G.; Saborido Silva, J.J.; Sagidova, N.; Sail, P.; Saitta, B.; Salzmann, C.; Sannino, M.; Santacesaria, R.; Santamarina Rios, C.; Santinelli, R.; Santovetti, E.; Sapunov, M.; Sarti, A.; Satriano, C.; Satta, A.; Savrie, M.; Savrina, D.; Schaack, P.; Schiller, M.; Schleich, S.; Schmelling, M.; Schmidt, B.; Schneider, O.; Schopper, A.; Schune, M.H.; Schwemmer, R.; Sciubba, A.; Seco, M.; Semennikov, A.; Senderowska, K.; Sepp, I.; Serra, N.; Serrano, J.; Seyfert, P.; Shao, B.; Shapkin, M.; Shapoval, I.; Shatalov, P.; Shcheglov, Y.; Shears, T.; Shekhtman, L.; Shevchenko, O.; Shevchenko, V.; Shires, A.; Silva Coutinho, R.; Skottowe, H.P.; Skwarnicki, T.; Smith, A.C.; Smith, N.A.; Sobczak, K.; Soler, F.J.P.; Solomin, A.; Soomro, F.; Souza De Paula, B.; Spaan, B.; Sparkes, A.; Spradlin, P.; Stagni, F.; Stahl, S.; Steinkamp, O.; Stoica, S.; Stone, S.; Storaci, B.; Straticiuc, M.; Straumann, U.; Styles, N.; Subbiah, V.K.; Swientek, S.; Szczekowski, M.; Szczypka, P.; Szumlak, T.; T'Jampens, S.; Teodorescu, E.; Teubert, F.; Thomas, C.; Thomas, E.; van Tilburg, J.; Tisserand, V.; Tobin, M.; Topp-Joergensen, S.; Tran, M.T.; Tsaregorodtsev, A.; Tuning, N.; Ubeda Garcia, M.; Ukleja, A.; Urquijo, P.; Uwer, U.; Vagnoni, V.; Valenti, G.; Vazquez Gomez, R.; Vazquez Regueiro, P.; Vecchi, S.; Velthuis, J.J.; Veltri, M.; Vervink, K.; Viaud, B.; Videau, I.; Vieira, D.; Vilasis-Cardona, X.; Visniakov, J.; Vollhardt, A.; Voong, D.; Vorobyev, A.; Voss, H.; Wacker, K.; Wandernoth, S.; Wang, J.; Ward, D.R.; Webber, A.D.; Websdale, D.; Whitehead, M.; Wiedner, D.; Wiggers, L.; Wilkinson, G.; Williams, M.P.; Williams, M.; Wilson, F.F.; Wishahi, J.; Witek, M.; Witzeling, W.; Wotton, S.A.; Wyllie, K.; Xie, Y.; Xing, F.; Yang, Z.; Young, R.; Yushchenko, O.; Zavertyaev, M.; Zhang, F.; Zhang, L.; Zhang, W.C.; Zhang, Y.; Zhelezov, A.; Zhong, L.; Zverev, E.; Zvyagin, A.

    2011-01-01

    A model-independent search for direct CP violation in the Cabibbo suppressed decay $D^+ \\to K^- K^+\\pi^+$ in a sample of approximately 370,000 decays is carried out. The data were collected by the LHCb experiment in 2010 and correspond to an integrated luminosity of 35 pb$^{-1}$. The normalized Dalitz plot distributions for $D^+$ and $D^-$ are compared using four different binning schemes that are sensitive to different manifestations of CP violation. No evidence for CP asymmetry is found.

  10. An approach in building a chemical compound search engine in oracle database.

    Science.gov (United States)

    Wang, H; Volarath, P; Harrison, R

    2005-01-01

    A searching or identifying of chemical compounds is an important process in drug design and in chemistry research. An efficient search engine involves a close coupling of the search algorithm and database implementation. The database must process chemical structures, which demands the approaches to represent, store, and retrieve structures in a database system. In this paper, a general database framework for working as a chemical compound search engine in Oracle database is described. The framework is devoted to eliminate data type constrains for potential search algorithms, which is a crucial step toward building a domain specific query language on top of SQL. A search engine implementation based on the database framework is also demonstrated. The convenience of the implementation emphasizes the efficiency and simplicity of the framework.

  11. Using Growing Self-Organising Maps to Improve the Binning Process in Environmental Whole-Genome Shotgun Sequencing

    Science.gov (United States)

    Chan, Chon-Kit Kenneth; Hsu, Arthur L.; Tang, Sen-Lin; Halgamuge, Saman K.

    2008-01-01

    Metagenomic projects using whole-genome shotgun (WGS) sequencing produces many unassembled DNA sequences and small contigs. The step of clustering these sequences, based on biological and molecular features, is called binning. A reported strategy for binning that combines oligonucleotide frequency and self-organising maps (SOM) shows high potential. We improve this strategy by identifying suitable training features, implementing a better clustering algorithm, and defining quantitative measures for assessing results. We investigated the suitability of each of di-, tri-, tetra-, and pentanucleotide frequencies. The results show that dinucleotide frequency is not a sufficiently strong signature for binning 10 kb long DNA sequences, compared to the other three. Furthermore, we observed that increased order of oligonucleotide frequency may deteriorate the assignment result in some cases, which indicates the possible existence of optimal species-specific oligonucleotide frequency. We replaced SOM with growing self-organising map (GSOM) where comparable results are obtained while gaining 7%–15% speed improvement. PMID:18288261

  12. An adaptive-binning method for generating constant-uncertainty/constant-significance light curves with Fermi-LAT data

    International Nuclear Information System (INIS)

    Lott, B.; Escande, L.; Larsson, S.; Ballet, J.

    2012-01-01

    Here, we present a method enabling the creation of constant-uncertainty/constant-significance light curves with the data of the Fermi-Large Area Telescope (LAT). The adaptive-binning method enables more information to be encapsulated within the light curve than with the fixed-binning method. Although primarily developed for blazar studies, it can be applied to any sources. Furthermore, this method allows the starting and ending times of each interval to be calculated in a simple and quick way during a first step. The reported mean flux and spectral index (assuming the spectrum is a power-law distribution) in the interval are calculated via the standard LAT analysis during a second step. In the absence of major caveats associated with this method Monte-Carlo simulations have been established. We present the performance of this method in determining duty cycles as well as power-density spectra relative to the traditional fixed-binning method.

  13. Search for CP violation in the decay $D^+ \\to \\pi^-\\pi^+\\pi^+$

    CERN Document Server

    Aaij, R; Adinolfi, M; Adrover, C; Affolder, A; Ajaltouni, Z; Albrecht, J; Alessio, F; Alexander, M; Ali, S; Alkhazov, G; Alvarez Cartelle, P; Alves Jr, A A; Amato, S; Amerio, S; Amhis, Y; Anderlini, L; Anderson, J; Andreassen, R; Andreotti, M; Andrews, J E; Appleby, R B; Aquines Gutierrez, O; Archilli, F; Artamonov, A; Artuso, M; Aslanides, E; Auriemma, G; Baalouch, M; Bachmann, S; Back, J J; Badalov, A; Baesso, C; Balagura, V; Baldini, W; Barlow, R J; Barschel, C; Barsuk, S; Barter, W; Batozskaya, V; Bauer, Th; Bay, A; Beddow, J; Bedeschi, F; Bediaga, I; Belogurov, S; Belous, K; Belyaev, I; Ben-Haim, E; Bencivenni, G; Benson, S; Benton, J; Berezhnoy, A; Bernet, R; Bettler, M -O; van Beuzekom, M; Bien, A; Bifani, S; Bird, T; Bizzeti, A; Bjørnstad, P M; Blake, T; Blanc, F; Blouw, J; Blusk, S; Bocci, V; Bondar, A; Bondar, N; Bonivento, W; Borghi, S; Borgia, A; Bowcock, T J V; Bowen, E; Bozzi, C; Brambach, T; van den Brand, J; Bressieux, J; Brett, D; Britsch, M; Britton, T; Brook, N H; Brown, H; Bursche, A; Busetto, G; Buytaert, J; Cadeddu, S; Calabrese, R; Callot, O; Calvi, M; Calvo Gomez, M; Camboni, A; Campana, P; Campora Perez, D; Carbone, A; Carboni, G; Cardinale, R; Cardini, A; Carranza-Mejia, H; Carson, L; Carvalho Akiba, K; Casse, G; Castillo Garcia, L; Cattaneo, M; Cauet, Ch; Cenci, R; Charles, M; Charpentier, Ph; Cheung, S -F; Chiapolini, N; Chrzaszcz, M; Ciba, K; Cid Vidal, X; Ciezarek, G; Clarke, P E L; Clemencic, M; Cliff, H V; Closier, J; Coca, C; Coco, V; Cogan, J; Cogneras, E; Collins, P; Comerma-Montells, A; Contu, A; Cook, A; Coombes, M; Coquereau, S; Corti, G; Couturier, B; Cowan, G A; Craik, D C; Cruz Torres, M; Cunliffe, S; Currie, R; D'Ambrosio, C; Dalseno, J; David, P; David, P N Y; Davis, A; De Bonis, I; De Bruyn, K; De Capua, S; De Cian, M; De Miranda, J M; De Paula, L; De Silva, W; De Simone, P; Decamp, D; Deckenhoff, M; Del Buono, L; Déléage, N; Derkach, D; Deschamps, O; Dettori, F; Di Canto, A; Dijkstra, H; Dogaru, M; Donleavy, S; Dordei, F; Dosil Suárez, A; Dossett, D; Dovbnya, A; Dupertuis, F; Durante, P; Dzhelyadin, R; Dziurda, A; Dzyuba, A; Easo, S; Egede, U; Egorychev, V; Eidelman, S; van Eijk, D; Eisenhardt, S; Eitschberger, U; Ekelhof, R; Eklund, L; El Rifai, I; Elsasser, Ch; Falabella, A; Färber, C; Farinelli, C; Farry, S; Ferguson, D; Fernandez Albor, V; Ferreira Rodrigues, F; Ferro-Luzzi, M; Filippov, S; Fiore, M; Fiorini, M; Fitzpatrick, C; Fontana, M; Fontanelli, F; Forty, R; Francisco, O; Frank, M; Frei, C; Frosini, M; Furfaro, E; Gallas Torreira, A; Galli, D; Gandelman, M; Gandini, P; Gao, Y; Garofoli, J; Garosi, P; Garra Tico, J; Garrido, L; Gaspar, C; Gauld, R; Gersabeck, E; Gersabeck, M; Gershon, T; Ghez, Ph; Gibson, V; Giubega, L; Gligorov, V V; Göbel, C; Golubkov, D; Golutvin, A; Gomes, A; Gorbounov, P; Gordon, H; Grabalosa Gándara, M; Graciani Diaz, R; Granado Cardoso, L A; Graugés, E; Graziani, G; Grecu, A; Greening, E; Gregson, S; Griffith, P; Grillo, L; Grünberg, O; Gui, B; Gushchin, E; Guz, Yu; Gys, T; Hadjivasiliou, C; Haefeli, G; Haen, C; Hafkenscheid, T W; Haines, S C; Hall, S; Hamilton, B; Hampson, T; Hansmann-Menzemer, S; Harnew, N; Harnew, S T; Harrison, J; Hartmann, T; He, J; Head, T; Heijne, V; Hennessy, K; Henrard, P; Hernando Morata, J A; van Herwijnen, E; Heß, M; Hicheur, A; Hicks, E; Hill, D; Hoballah, M; Hombach, C; Hulsbergen, W; Hunt, P; Huse, T; Hussain, N; Hutchcroft, D; Hynds, D; Iakovenko, V; Idzik, M; Ilten, P; Jacobsson, R; Jaeger, A; Jans, E; Jaton, P; Jawahery, A; Jing, F; John, M; Johnson, D; Jones, C R; Joram, C; Jost, B; Kaballo, M; Kandybei, S; Kanso, W; Karacson, M; Karbach, T M; Kenyon, I R; Ketel, T; Khanji, B; Kochebina, O; Komarov, I; Koopman, R F; Koppenburg, P; Korolev, M; Kozlinskiy, A; Kravchuk, L; Kreplin, K; Kreps, M; Krocker, G; Krokovny, P; Kruse, F; Kucharczyk, M; Kudryavtsev, V; Kurek, K; Kvaratskheliya, T; La Thi, V N; Lacarrere, D; Lafferty, G; Lai, A; Lambert, D; Lambert, R W; Lanciotti, E; Lanfranchi, G; Langenbruch, C; Latham, T; Lazzeroni, C; Le Gac, R; van Leerdam, J; Lees, J -P; Lefèvre, R; Leflat, A; Lefrançois, J; Leo, S; Leroy, O; Lesiak, T; Leverington, B; Li, Y; Li Gioi, L; Liles, M; Lindner, R; Linn, C; Liu, B; Liu, G; Lohn, S; Longstaff, I; Lopes, J H; Lopez-March, N; Lu, H; Lucchesi, D; Luisier, J; Luo, H; Luppi, E; Lupton, O; Machefert, F; Machikhiliyan, I V; Maciuc, F; Maev, O; Malde, S; Manca, G; Mancinelli, G; Maratas, J; Marconi, U; Marino, P; Märki, R; Marks, J; Martellotti, G; Martens, A; Martín Sánchez, A; Martinelli, M; Martinez Santos, D; Martins Tostes, D; Martynov, A; Massafferri, A; Matev, R; Mathe, Z; Matteuzzi, C; Maurice, E; Mazurov, A; McCann, M; McCarthy, J; McNab, A; McNulty, R; McSkelly, B; Meadows, B; Meier, F; Meissner, M; Merk, M; Milanes, D A; Minard, M -N; Molina Rodriguez, J; Monteil, S; Moran, D; Morawski, P; Mordà, A; Morello, M J; Mountain, R; Mous, I; Muheim, F; Müller, K; Muresan, R; Muryn, B; Muster, B; Naik, P; Nakada, T; Nandakumar, R; Nasteva, I; Needham, M; Neubert, S; Neufeld, N; Nguyen, A D; Nguyen, T D; Nguyen-Mau, C; Nicol, M; Niess, V; Niet, R; Nikitin, N; Nikodem, T; Nomerotski, A; Novoselov, A; Oblakowska-Mucha, A; Obraztsov, V; Oggero, S; Ogilvy, S; Okhrimenko, O; Oldeman, R; Onderwater, G; Orlandea, M; Otalora Goicochea, J M; Owen, P; Oyanguren, A; Pal, B K; Palano, A; Palutan, M; Panman, J; Papanestis, A; Pappagallo, M; Parkes, C; Parkinson, C J; Passaleva, G; Patel, G D; Patel, M; Patrignani, C; Pavel-Nicorescu, C; Pazos Alvarez, A; Pearce, A; Pellegrino, A; Penso, G; Pepe Altarelli, M; Perazzini, S; Perez Trigo, E; Pérez-Calero Yzquierdo, A; Perret, P; Perrin-Terrin, M; Pescatore, L; Pesen, E; Pessina, G; Petridis, K; Petrolini, A; Picatoste Olloqui, E; Pietrzyk, B; Pilař, T; Pinci, D; Playfer, S; Plo Casasus, M; Polci, F; Polok, G; Poluektov, A; Polycarpo, E; Popov, A; Popov, D; Popovici, B; Potterat, C; Powell, A; Prisciandaro, J; Pritchard, A; Prouve, C; Pugatch, V; Puig Navarro, A; Punzi, G; Qian, W; Rachwal, B; Rademacker, J H; Rakotomiaramanana, B; Rangel, M S; Raniuk, I; Rauschmayr, N; Raven, G; Redford, S; Reichert, S; Reid, M M; dos Reis, A C; Ricciardi, S; Richards, A; Rinnert, K; Rives Molina, V; Roa Romero, D A; Robbe, P; Roberts, D A; Rodrigues, A B; Rodrigues, E; Rodriguez Perez, P; Roiser, S; Romanovsky, V; Romero Vidal, A; Rotondo, M; Rouvinet, J; Ruf, T; Ruffini, F; Ruiz, H; Ruiz Valls, P; Sabatino, G; Saborido Silva, J J; Sagidova, N; Sail, P; Saitta, B; Salustino Guimaraes, V; Sanmartin Sedes, B; Santacesaria, R; Santamarina Rios, C; Santovetti, E; Sapunov, M; Sarti, A; Satriano, C; Satta, A; Savrie, M; Savrina, D; Schiller, M; Schindler, H; Schlupp, M; Schmelling, M; Schmidt, B; Schneider, O; Schopper, A; Schune, M -H; Schwemmer, R; Sciascia, B; Sciubba, A; Seco, M; Semennikov, A; Senderowska, K; Sepp, I; Serra, N; Serrano, J; Seyfert, P; Shapkin, M; Shapoval, I; Shcheglov, Y; Shears, T; Shekhtman, L; Shevchenko, O; Shevchenko, V; Shires, A; Silva Coutinho, R; Sirendi, M; Skidmore, N; Skwarnicki, T; Smith, N A; Smith, E; Smith, E; Smith, J; Smith, M; Sokoloff, M D; Soler, F J P; Soomro, F; Souza, D; Souza De Paula, B; Spaan, B; Sparkes, A; Spradlin, P; Stagni, F; Stahl, S; Steinkamp, O; Stevenson, S; Stoica, S; Stone, S; Storaci, B; Stracka, S; Straticiuc, M; Straumann, U; Subbiah, V K; Sun, L; Sutcliffe, W; Swientek, S; Syropoulos, V; Szczekowski, M; Szczypka, P; Szilard, D; Szumlak, T; T'Jampens, S; Teklishyn, M; Tellarini, G; Teodorescu, E; Teubert, F; Thomas, C; Thomas, E; van Tilburg, J; Tisserand, V; Tobin, M; Tolk, S; Tomassetti, L; Tonelli, D; Topp-Joergensen, S; Torr, N; Tournefier, E; Tourneur, S; Tran, M T; Tresch, M; Tsaregorodtsev, A; Tsopelas, P; Tuning, N; Ubeda Garcia, M; Ukleja, A; Ustyuzhanin, A; Uwer, U; Vagnoni, V; Valenti, G; Vallier, A; Vazquez Gomez, R; Vazquez Regueiro, P; Vázquez Sierra, C; Vecchi, S; Velthuis, J J; Veltri, M; Veneziano, G; Vesterinen, M; Viaud, B; Vieira, D; Vilasis-Cardona, X; Vollhardt, A; Volyanskyy, D; Voong, D; Vorobyev, A; Vorobyev, V; Voß, C; Voss, H; Waldi, R; Wallace, C; Wallace, R; Wandernoth, S; Wang, J; Ward, D R; Watson, N K; Webber, A D; Websdale, D; Whitehead, M; Wicht, J; Wiechczynski, J; Wiedner, D; Wiggers, L; Wilkinson, G; Williams, M P; Williams, M; Wilson, F F; Wimberley, J; Wishahi, J; Wislicki, W; Witek, M; Wormser, G; Wotton, S A; Wright, S; Wu, S; Wyllie, K; Xie, Y; Xing, Z; Yang, Z; Yuan, X; Yushchenko, O; Zangoli, M; Zavertyaev, M; Zhang, F; Zhang, L; Zhang, W C; Zhang, Y; Zhelezov, A; Zhokhov, A; Zhong, L; Zvyagin, A

    2014-01-01

    A search for CP violation in the phase space of the decay $D^+\\to\\pi^-\\pi^+\\pi^+$ is reported using $pp$ collision data, corresponding to an integrated luminosity of 1.0 fb$^{-1}$, collected by the LHCb experiment at a centre-of-mass energy of 7 TeV. The Dalitz plot distributions for $3.1\\times 10^6$ $D^+$ and $D^-$ candidates are compared with binned and unbinned model-independent techniques. No evidence for CP violation is found.

  14. The effect of stocking density and bin feeder space on performance ...

    African Journals Online (AJOL)

    Unknown

    The effect of stocking density and bin feeder space on performance in pigs. G.A. Lavers# and N.S. Ferguson. School of Agricultural Sciences & Agribusiness, University of Natal, P Bag X01, Scottsville 3209. #Email: lavers@agric.unp.ac.za. Introduction. Pigs housed individually have been shown to have higher feed intakes ...

  15. Matriz binária RiC: classificação filogenética da informação arquivística

    OpenAIRE

    Macedo, Laureano Secundino Ascensão de

    2017-01-01

    Ascensão de Macedo, L. S., 2017, "Matriz binária RiC: classificação filogenética da informação arquivística", doi:10.7910/DVN/ERE8HL, Harvard Dataverse, V1 Constam três folhas: 1 - matriz binária com propriedades RiC e taxa (tipologias documentais); 2 - matriz binária simples (processamento em DendroUPGMA); 3 - 3 outputs de DendroUPGMA: matriz bicaudal de similaridade, de distâncias e formato Newick. (2017-01-18)

  16. Single-Cell-Genomics-Facilitated Read Binning of Candidate Phylum EM19 Genomes from Geothermal Spring Metagenomes.

    Science.gov (United States)

    Becraft, Eric D; Dodsworth, Jeremy A; Murugapiran, Senthil K; Ohlsson, J Ingemar; Briggs, Brandon R; Kanbar, Jad; De Vlaminck, Iwijn; Quake, Stephen R; Dong, Hailiang; Hedlund, Brian P; Swingley, Wesley D

    2016-02-15

    The vast majority of microbial life remains uncatalogued due to the inability to cultivate these organisms in the laboratory. This "microbial dark matter" represents a substantial portion of the tree of life and of the populations that contribute to chemical cycling in many ecosystems. In this work, we leveraged an existing single-cell genomic data set representing the candidate bacterial phylum "Calescamantes" (EM19) to calibrate machine learning algorithms and define metagenomic bins directly from pyrosequencing reads derived from Great Boiling Spring in the U.S. Great Basin. Compared to other assembly-based methods, taxonomic binning with a read-based machine learning approach yielded final assemblies with the highest predicted genome completeness of any method tested. Read-first binning subsequently was used to extract Calescamantes bins from all metagenomes with abundant Calescamantes populations, including metagenomes from Octopus Spring and Bison Pool in Yellowstone National Park and Gongxiaoshe Spring in Yunnan Province, China. Metabolic reconstruction suggests that Calescamantes are heterotrophic, facultative anaerobes, which can utilize oxidized nitrogen sources as terminal electron acceptors for respiration in the absence of oxygen and use proteins as their primary carbon source. Despite their phylogenetic divergence, the geographically separate Calescamantes populations were highly similar in their predicted metabolic capabilities and core gene content, respiring O2, or oxidized nitrogen species for energy conservation in distant but chemically similar hot springs. Copyright © 2016, American Society for Microbiology. All Rights Reserved.

  17. PhyloPythiaS+: a self-training method for the rapid reconstruction of low-ranking taxonomic bins from metagenomes

    Directory of Open Access Journals (Sweden)

    Ivan Gregor

    2016-02-01

    Full Text Available Background. Metagenomics is an approach for characterizing environmental microbial communities in situ, it allows their functional and taxonomic characterization and to recover sequences from uncultured taxa. This is often achieved by a combination of sequence assembly and binning, where sequences are grouped into ‘bins’ representing taxa of the underlying microbial community. Assignment to low-ranking taxonomic bins is an important challenge for binning methods as is scalability to Gb-sized datasets generated with deep sequencing techniques. One of the best available methods for species bins recovery from deep-branching phyla is the expert-trained PhyloPythiaS package, where a human expert decides on the taxa to incorporate in the model and identifies ‘training’ sequences based on marker genes directly from the sample. Due to the manual effort involved, this approach does not scale to multiple metagenome samples and requires substantial expertise, which researchers who are new to the area do not have. Results. We have developed PhyloPythiaS+, a successor to our PhyloPythia(S software. The new (+ component performs the work previously done by the human expert. PhyloPythiaS+ also includes a new k-mer counting algorithm, which accelerated the simultaneous counting of 4–6-mers used for taxonomic binning 100-fold and reduced the overall execution time of the software by a factor of three. Our software allows to analyze Gb-sized metagenomes with inexpensive hardware, and to recover species or genera-level bins with low error rates in a fully automated fashion. PhyloPythiaS+ was compared to MEGAN, taxator-tk, Kraken and the generic PhyloPythiaS model. The results showed that PhyloPythiaS+ performs especially well for samples originating from novel environments in comparison to the other methods. Availability. PhyloPythiaS+ in a virtual machine is available for installation under Windows, Unix systems or OS X on: https://github.com/algbioi/ppsp/wiki.

  18. Search for supersymmetry with jets, missing transverse momentum, tau leptons and one light lepton at the ATLAS detector

    Energy Technology Data Exchange (ETDEWEB)

    Bechtle, Philip; Desch, Klaus; Schaepe, Steffen; Schultens, Martin [University of Bonn (Germany)

    2015-07-01

    The search for supersymmetric extensions of the Standard Model of particle physics (SUSY) is one of the main objectives in the physics program of the ATLAS experiment at the Large Hadron Collider (LHC). However, there has been no evidence for Supersymmetry during the first data taking period in 2010 and 2012 and stringent exclusion limits could be set in various signal models. For the second run of the LHC improved analysis methods will be important. One possibility to reach better exclusion power is using a multi-bin shape fit approach rather than a simple one-bin exclusion fit. The gain from such binned signal regions has been studied for an analysis using final states with tau leptons and one lighter lepton (electron or muon). The analysis was performed on the full 2012 LHC dataset with an integrated luminosity of 21 fb{sup -1} and the results were interpreted in four different SUSY scenarios: Gauge-Mediated Supersymmetry Breaking (GMSB), Natural Gauge Mediation (NGM), Gravity Mediated Symmetry Breaking (MSUGRA) and Bilinear R-Parity Violation (BRPV).

  19. BInGaN alloys nearly lattice-matched to GaN for high-power high-efficiency visible LEDs

    Science.gov (United States)

    Williams, Logan; Kioupakis, Emmanouil

    2017-11-01

    InGaN-based visible light-emitting diodes (LEDs) find commercial applications for solid-state lighting and displays, but lattice mismatch limits the thickness of InGaN quantum wells that can be grown on GaN with high crystalline quality. Since narrower wells operate at a higher carrier density for a given current density, they increase the fraction of carriers lost to Auger recombination and lower the efficiency. The incorporation of boron, a smaller group-III element, into InGaN alloys is a promising method to eliminate the lattice mismatch and realize high-power, high-efficiency visible LEDs with thick active regions. In this work, we apply predictive calculations based on hybrid density functional theory to investigate the thermodynamic, structural, and electronic properties of BInGaN alloys. Our results show that BInGaN alloys with a B:In ratio of 2:3 are better lattice matched to GaN compared to InGaN and, for indium fractions less than 0.2, nearly lattice matched. Deviations from Vegard's law appear as bowing of the in-plane lattice constant with respect to composition. Our thermodynamics calculations demonstrate that the solubility of boron is higher in InGaN than in pure GaN. Varying the Ga mole fraction while keeping the B:In ratio constant enables the adjustment of the (direct) gap in the 1.75-3.39 eV range, which covers the entire visible spectrum. Holes are strongly localized in non-bonded N 2p states caused by local bond planarization near boron atoms. Our results indicate that BInGaN alloys are promising for fabricating nitride heterostructures with thick active regions for high-power, high-efficiency LEDs.

  20. Efficient Entanglement Concentration of Nonlocal Two-Photon Polarization-Time-Bin Hyperentangled States

    Science.gov (United States)

    Wang, Zi-Hang; Yu, Wen-Xuan; Wu, Xiao-Yuan; Gao, Cheng-Yan; Alzahrani, Faris; Hobiny, Aatef; Deng, Fu-Guo

    2018-03-01

    We present two different hyperentanglement concentration protocols (hyper-ECPs) for two-photon systems in nonlocal polarization-time-bin hyperentangled states with known parameters, including Bell-like and cluster-like states, resorting to the parameter splitting method. They require only one of two parties in quantum communication to operate her photon in the process of entanglement concentration, not two, and they have the maximal success probability. They work with linear optical elements and have good feasibility in experiment, especially in the case that there are a big number of quantum data exchanged as the parties can obtain the information about the parameters of the nonlocal hyperentangled states by sampling a subset of nonlocal hyperentangled two-photon systems and measuring them. As the quantum state of photons in the time-bin degree of freedom suffers from less noise in an optical-fiber channel, these hyper-ECPs may have good applications in practical long-distance quantum communication in the future.

  1. Personalization in professional academic search

    NARCIS (Netherlands)

    Verberne, S.; Sappelli, M.; Sørensen, D.R.; Kraaij, W.

    2013-01-01

    In this paper, we investigated how academic search can profit from personalization by incorporating query history and background knowledge in the ranking of the results. We implemented both techniques in a language modelling framework, using the Indri search engine. For our experiments, we used the

  2. Evaluation of five sampling methods for Liposcelis entomophila (Enderlein) and L. decolor (Pearman) (Psocoptera: Liposcelididae) in steel bins containing wheat

    Science.gov (United States)

    An evaluation of five sampling methods for studying psocid population levels was conducted in two steel bins containing 32.6 metric tonnes of wheat in Manhattan, KS. Psocids were sampled using a 1.2-m open-ended trier, corrugated cardboard refuges placed on the underside of the bin hatch or the surf...

  3. The Peril of Hasty Triumphalism and Osama bin Laden’s Death

    Directory of Open Access Journals (Sweden)

    Eugenio Lilli

    2011-05-01

    Full Text Available On May 1, 2011 the headlines of a large number of newspapers and TV channels around the world were saying “justice has been done”. Those were the words used by the US President Barack Obama to announce to the world the killing of Osama bin Laden, the number one terrorist on the US most-wanted list.

  4. Cardinality reasoning for bin-packing constraint : Application to a tank allocation problem

    NARCIS (Netherlands)

    Schaus, Pierre; Régin, Jean Charles; Van Schaeren, Rowan; Dullaert, Wout; Raa, Birger

    2012-01-01

    Flow reasoning has been successfully used in CP for more than a decade. It was originally introduced by Régin in the well-known Alldifferent and Global Cardinality Constraint (GCC) available in most of the CP solvers. The BinPacking constraint was introduced by Shaw and mainly uses an independent

  5. SANSparallel: interactive homology search against Uniprot.

    Science.gov (United States)

    Somervuo, Panu; Holm, Liisa

    2015-07-01

    Proteins evolve by mutations and natural selection. The network of sequence similarities is a rich source for mining homologous relationships that inform on protein structure and function. There are many servers available to browse the network of homology relationships but one has to wait up to a minute for results. The SANSparallel webserver provides protein sequence database searches with immediate response and professional alignment visualization by third-party software. The output is a list, pairwise alignment or stacked alignment of sequence-similar proteins from Uniprot, UniRef90/50, Swissprot or Protein Data Bank. The stacked alignments are viewed in Jalview or as sequence logos. The database search uses the suffix array neighborhood search (SANS) method, which has been re-implemented as a client-server, improved and parallelized. The method is extremely fast and as sensitive as BLAST above 50% sequence identity. Benchmarks show that the method is highly competitive compared to previously published fast database search programs: UBLAST, DIAMOND, LAST, LAMBDA, RAPSEARCH2 and BLAT. The web server can be accessed interactively or programmatically at http://ekhidna2.biocenter.helsinki.fi/cgi-bin/sans/sans.cgi. It can be used to make protein functional annotation pipelines more efficient, and it is useful in interactive exploration of the detailed evidence supporting the annotation of particular proteins of interest. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  6. Search algorithms as a framework for the optimization of drug combinations.

    Directory of Open Access Journals (Sweden)

    Diego Calzolari

    2008-12-01

    Full Text Available Combination therapies are often needed for effective clinical outcomes in the management of complex diseases, but presently they are generally based on empirical clinical experience. Here we suggest a novel application of search algorithms -- originally developed for digital communication -- modified to optimize combinations of therapeutic interventions. In biological experiments measuring the restoration of the decline with age in heart function and exercise capacity in Drosophila melanogaster, we found that search algorithms correctly identified optimal combinations of four drugs using only one-third of the tests performed in a fully factorial search. In experiments identifying combinations of three doses of up to six drugs for selective killing of human cancer cells, search algorithms resulted in a highly significant enrichment of selective combinations compared with random searches. In simulations using a network model of cell death, we found that the search algorithms identified the optimal combinations of 6-9 interventions in 80-90% of tests, compared with 15-30% for an equivalent random search. These findings suggest that modified search algorithms from information theory have the potential to enhance the discovery of novel therapeutic drug combinations. This report also helps to frame a biomedical problem that will benefit from an interdisciplinary effort and suggests a general strategy for its solution.

  7. Diviner lunar radiometer gridded brightness temperatures from geodesic binning of modeled fields of view

    Science.gov (United States)

    Sefton-Nash, E.; Williams, J.-P.; Greenhagen, B. T.; Aye, K.-M.; Paige, D. A.

    2017-12-01

    An approach is presented to efficiently produce high quality gridded data records from the large, global point-based dataset returned by the Diviner Lunar Radiometer Experiment aboard NASA's Lunar Reconnaissance Orbiter. The need to minimize data volume and processing time in production of science-ready map products is increasingly important with the growth in data volume of planetary datasets. Diviner makes on average >1400 observations per second of radiance that is reflected and emitted from the lunar surface, using 189 detectors divided into 9 spectral channels. Data management and processing bottlenecks are amplified by modeling every observation as a probability distribution function over the field of view, which can increase the required processing time by 2-3 orders of magnitude. Geometric corrections, such as projection of data points onto a digital elevation model, are numerically intensive and therefore it is desirable to perform them only once. Our approach reduces bottlenecks through parallel binning and efficient storage of a pre-processed database of observations. Database construction is via subdivision of a geodesic icosahedral grid, with a spatial resolution that can be tailored to suit the field of view of the observing instrument. Global geodesic grids with high spatial resolution are normally impractically memory intensive. We therefore demonstrate a minimum storage and highly parallel method to bin very large numbers of data points onto such a grid. A database of the pre-processed and binned points is then used for production of mapped data products that is significantly faster than if unprocessed points were used. We explore quality controls in the production of gridded data records by conditional interpolation, allowed only where data density is sufficient. The resultant effects on the spatial continuity and uncertainty in maps of lunar brightness temperatures is illustrated. We identify four binning regimes based on trades between the

  8. Amina Bin Qarrish de Tetuan: registros da vida de uma mulher marroquina do século XIX Amina Bin Qarrish of Tetuan: records of the life of a Moroccan woman of the 19th century

    Directory of Open Access Journals (Sweden)

    Nadia Erzijni

    2008-06-01

    Full Text Available Este artigo registra a tentativa de escrever a biografia de uma mulher de Tetuan do século XIX, Amina Bin Qarrish (morta em 1889, esposa de 'Abdalkrim ar-Razini (morto em 1909. Ela foi uma mulher rica, o último membro sobrevivente da família de Zawiyat Ben Qarrish, uma comunidade Sufi fundada em Tetuan no final do século XVII ou início do século XVIII. As principais fontes para esta biografia são uma coleção de documentos inéditos (documentos legais, cartas e anotações em cadernos do arquivo Razini em Tetuan. Esses documentos tratam de herança, casamento, divórcio, propriedade, procurações, presentes, awqaf, experiências de guerra e da vida familiar de Amina Bin Qarrish e de mulheres contemporâneas. Também é possível usar a história oral para auxiliar a interpretar esses documentos.This article records the attempt to write a biography of a woman of 19th century Tetuan, Amina Bin Qarrish (d.1889, wife of 'Abdalkrim ar-Razini (d.1909. She was a wealthy woman, the last surviving member of the family of the Zawiyat Ben Qarrish, a Sufi fraternity founded in Tetuan in the late 17th or early 18th century. The principal sources for the biography are a small collection of unpublished documents (legal documents, letters and jottings in notebooks in the Razini archive in Tetuan. These documents deal with the inheritance, marriage, divorce, property, power of attorney, gifts, awqaf, experience of war, and family life of Amina Bin Qarrish, and those of contemporary women. It is also possible to use oral history to help interpret these documents.

  9. Frequency-bin entanglement of ultra-narrow band non-degenerate photon pairs

    Science.gov (United States)

    Rieländer, Daniel; Lenhard, Andreas; Jime`nez Farìas, Osvaldo; Máttar, Alejandro; Cavalcanti, Daniel; Mazzera, Margherita; Acín, Antonio; de Riedmatten, Hugues

    2018-01-01

    We demonstrate frequency-bin entanglement between ultra-narrowband photons generated by cavity enhanced spontaneous parametric down conversion. Our source generates photon pairs in widely non-degenerate discrete frequency modes, with one photon resonant with a quantum memory material based on praseodymium doped crystals and the other photon at telecom wavelengths. Correlations between the frequency modes are analyzed using phase modulators and narrowband filters before detection. We show high-visibility two photon interference between the frequency modes, allowing us to infer a coherent superposition of the modes. We develop a model describing the state that we create and use it to estimate optimal measurements to achieve a violation of the Clauser-Horne (CH) Bell inequality under realistic assumptions. With these settings we perform a Bell test and show a significant violation of the CH inequality, thus proving the entanglement of the photons. Finally we demonstrate the compatibility with a quantum memory material by using a spectral hole in the praseodymium (Pr) doped crystal as spectral filter for measuring high-visibility two-photon interference. This demonstrates the feasibility of combining frequency-bin entangled photon pairs with Pr-based solid state quantum memories.

  10. Modal Bin Hybrid Model: A surface area consistent, triple-moment sectional method for use in process-oriented modeling of atmospheric aerosols

    Science.gov (United States)

    Kajino, Mizuo; Easter, Richard C.; Ghan, Steven J.

    2013-09-01

    triple-moment sectional (TMS) aerosol dynamics model, Modal Bin Hybrid Model (MBHM), has been developed. In addition to number and mass (volume), surface area is predicted (and preserved), which is important for aerosol processes and properties such as gas-to-particle mass transfer, heterogeneous reaction, and light extinction cross section. The performance of MBHM was evaluated against double-moment sectional (DMS) models with coarse (BIN4) to very fine (BIN256) size resolutions for simulating evolution of particles under simultaneously occurring nucleation, condensation, and coagulation processes (BINx resolution uses x sections to cover the 1 nm to 1 µm size range). Because MBHM gives a physically consistent form of the intrasectional distributions, errors and biases of MBHM at BIN4-8 resolution were almost equivalent to those of DMS at BIN16-32 resolution for various important variables such as the moments Mk (k: 0, 2, 3), dMk/dt, and the number and volume of particles larger than a certain diameter. Another important feature of MBHM is that only a single bin is adequate to simulate full aerosol dynamics for particles whose size distribution can be approximated by a single lognormal mode. This flexibility is useful for process-oriented (multicategory and/or mixing state) modeling: Primary aerosols whose size parameters would not differ substantially in time and space can be expressed by a single or a small number of modes, whereas secondary aerosols whose size changes drastically from 1 to several hundred nanometers can be expressed by a number of modes. Added dimensions can be applied to MBHM to represent mixing state or photochemical age for aerosol mixing state studies.

  11. A multistage framework for reliability-based distribution expansion planning considering distributed generations by a self-adaptive global-based harmony search algorithm

    International Nuclear Information System (INIS)

    Shivaie, Mojtaba; Ameli, Mohammad T.; Sepasian, Mohammad S.; Weinsier, Philip D.; Vahidinasab, Vahid

    2015-01-01

    In this paper, the authors present a new multistage framework for reliability-based Distribution Expansion Planning (DEP) in which expansion options are a reinforcement and/or installation of substations, feeders, and Distributed Generations (DGs). The proposed framework takes into account not only costs associated with investment, maintenance, and operation, but also expected customer interruption cost in the optimization as four problem objectives. At the same time, operational restrictions, Kirchhoff's laws, radial structure limitation, voltage limits, and capital expenditure budget restriction are considered as problem constraints. The proposed model is a non-convex optimization problem having a non-linear, mixed-integer nature. Hence, a hybrid Self-adaptive Global-based Harmony Search Algorithm (SGHSA) and Optimal Power Flow (OPF) were used and followed by a fuzzy satisfying method in order to obtain the final optimal solution. The SGHSA is a recently developed optimization algorithm which imitates the music improvisation process. In this process, the harmonists improvise their instrument pitches, searching for the perfect state of harmony. The planning methodology was demonstrated on the 27-node, 13.8-kV test system in order to demonstrate the feasibility and capability of the proposed model. Simulation results illustrated the sufficiency and profitableness of the newly developed framework, when compared with other methods. - Highlights: • A new multistage framework is presented for reliability-based DEP problem. • In this paper, DGs are considered as an expansion option to increase the flexibility of the proposed model. • In this paper, effective factors of DEP problem are incorporated as a multi-objective model. • In this paper, three new algorithms HSA, IHSA and SGHSA are proposed. • Results obtained by the proposed SGHSA algorithm are better than others

  12. Semantic Search of Web Services

    Science.gov (United States)

    Hao, Ke

    2013-01-01

    This dissertation addresses semantic search of Web services using natural language processing. We first survey various existing approaches, focusing on the fact that the expensive costs of current semantic annotation frameworks result in limited use of semantic search for large scale applications. We then propose a vector space model based service…

  13. Personalizing Web Search based on User Profile

    OpenAIRE

    Utage, Sharyu; Ahire, Vijaya

    2016-01-01

    Web Search engine is most widely used for information retrieval from World Wide Web. These Web Search engines help user to find most useful information. When different users Searches for same information, search engine provide same result without understanding who is submitted that query. Personalized web search it is search technique for proving useful result. This paper models preference of users as hierarchical user profiles. a framework is proposed called UPS. It generalizes profile and m...

  14. Voigt equivalent widths and spectral-bin single-line transmittances: Exact expansions and the MODTRAN®5 implementation

    Science.gov (United States)

    Berk, Alexander

    2013-03-01

    Exact expansions for Voigt line-shape total, line-tail and spectral bin equivalent widths and for Voigt finite spectral bin single-line transmittances have been derived in terms of optical depth dependent exponentially-scaled modified Bessel functions of integer order and optical depth independent Fourier integral coefficients. The series are convergent for the full range of Voigt line-shapes, from pure Doppler to pure Lorentzian. In the Lorentz limit, the expansion reduces to the Ladenburg and Reiche function for the total equivalent width. Analytic expressions are derived for the first 8 Fourier coefficients for pure Lorentzian lines, for pure Doppler lines and for Voigt lines with at most moderate Doppler dependence. A strong-line limit sum rule on the Fourier coefficients is enforced to define an additional Fourier coefficient and to optimize convergence of the truncated expansion. The moderate Doppler dependence scenario is applicable to and has been implemented in the MODTRAN5 atmospheric band model radiative transfer software. Finite-bin transmittances computed with the truncated expansions reduce transmittance residuals compared to the former Rodgers-Williams equivalent width based approach by ∼2 orders of magnitude.

  15. Moving beyond job search quantity: towards a conceptualization and self-regulatory framework of job search quality

    NARCIS (Netherlands)

    van Hooft, E.A.J.; Wanberg, C.R.; van Hoye, G.

    2013-01-01

    Job seeking is an important aspect throughout people’s careers. Extant theory and research has focused on one particular dimension of job search, that is, intensity/effort (i.e., job search quantity), posing that intensity/effort importantly affects employment success. The present conceptual paper

  16. Technology entrepreneurship : a process framework

    NARCIS (Netherlands)

    Zhou, Zhao

    2013-01-01

    Scholars are in search of an integrated perspective to explain entrepreneurship in a coherent way. This study sets to contribute to this search with a process framework for understanding similar patterns of entrepreneurship actions over time in different settings. This research uses the multi-case

  17. WAKTU PUASA ARAFAH PERSPEKTIF MUHAMMAD BIN SHALIH AL ‘UTSAYMIN: Telaah Kajian Hukum Islam dan Astronomi Islam

    Directory of Open Access Journals (Sweden)

    Benny Afwadzi

    2017-12-01

    Full Text Available All this time there was a different opinion about the time for Arafah fasting. Whether to comply with the provisions of Saudi Arabia or adjust the territory of each person. In Saudi Arabia, there appears a mufti named Muhammad bin Shalih al ‘Utsaymin who holds that fasting of Arafah must follow the country where a person lives. This opinion is interesting because it is different from other Salafis, such as ‘Abd al ‘Aziz bin Baz, Abdul Hakim bin Amir Abdat and HTI. Using the analytical tools of Islamic law and Islamic astronomy, the authors conclude that the fatwa issued by al ‘Utsaymin is considered quite representative, because considering the locality of a country, realizing the time of worship should adjust the kamariyah time of the country, and also in accordance with the mathla‘ in the form of mathla‘ wilayah al hukmi. Opinions as expressed by al ‘Utsaymin is conformable with the implementation of the time of the fasting of Arafat by the majority of Muslims in Indonesia.

  18. Search Engines for Tomorrow's Scholars, Part Two

    Science.gov (United States)

    Fagan, Jody Condit

    2012-01-01

    This two-part article considers how well some of today's search tools support scholars' work. The first part of the article reviewed Google Scholar and Microsoft Academic Search using a modified version of Carole L. Palmer, Lauren C. Teffeau, and Carrier M. Pirmann's framework (2009). Microsoft Academic Search is a strong contender when…

  19. Optical Extinction Measurements of Dust Density in the GMRO Regolith Test Bin

    Science.gov (United States)

    Lane, J.; Mantovani, J.; Mueller, R.; Nugent, M.; Nick, A.; Schuler, J.; Townsend, I.

    2016-01-01

    A regolith simulant test bin was constructed and completed in the Granular Mechanics and Regolith Operations (GMRO) Lab in 2013. This Planetary Regolith Test Bed (PRTB) is a 64 sq m x 1 m deep test bin, is housed in a climate-controlled facility, and contains 120 MT of lunar-regolith simulant, called Black Point-1 or BP-1, from Black Point, AZ. One of the current uses of the test bin is to study the effects of difficult lighting and dust conditions on Telerobotic Perception Systems to better assess and refine regolith operations for asteroid, Mars and polar lunar missions. Low illumination and low angle of incidence lighting pose significant problems to computer vision and human perception. Levitated dust on Asteroids interferes with imaging and degrades depth perception. Dust Storms on Mars pose a significant problem. Due to these factors, the likely performance of telerobotics is poorly understood for future missions. Current space telerobotic systems are only operated in bright lighting and dust-free conditions. This technology development testing will identify: (1) the impact of degraded lighting and environmental dust on computer vision and operator perception, (2) potential methods and procedures for mitigating these impacts, (3) requirements for telerobotic perception systems for asteroid capture, Mars dust storms and lunar regolith ISRU missions. In order to solve some of the Telerobotic Perception system problems, a plume erosion sensor (PES) was developed in the Lunar Regolith Simulant Bin (LRSB), containing 2 MT of JSC-1a lunar simulant. PES is simply a laser and digital camera with a white target. Two modes of operation have been investigated: (1) single laser spot - the brightness of the spot is dependent on the optical extinction due to dust and is thus an indirect measure of particle number density, and (2) side-scatter - the camera images the laser from the side, showing beam entrance into the dust cloud and the boundary between dust and void. Both

  20. Adaptive Motion Planning in Bin-Picking with Object Uncertainties

    DEFF Research Database (Denmark)

    Iversen, Thomas Fridolin; Ellekilde, Lars-Peter; Miró, Jaime Valls

    2017-01-01

    Doing motion planning for bin-picking with object uncertainties requires either a re-grasp of picked objects or an online sensor system. Using the latter is advantageous in terms of computational time, as no time is wasted doing an extra pick and place action. It does, however, put extra...... requirements on the motion planner, as the target position may change on-the-fly. This paper solves that problem by using a state adjusting Partial Observable Markov Decision Process, where the state space is modified between runs, to better fit earlier solved problems. The approach relies on a set...

  1. Effects of Number and Location of Bins on Plastic Recycling at a University

    Science.gov (United States)

    O'Connor, Ryan T.; Lerman, Dorothea C.; Fritz, Jennifer N.; Hodde, Henry B.

    2010-01-01

    The proportion of plastic bottles that consumers placed in appropriate recycling receptacles rather than trash bins was examined across 3 buildings on a university campus. We extended previous research on interventions to increase recycling by controlling the number of recycling receptacles across conditions and by examining receptacle location…

  2. Com obtenir un Model de Regressió Logística Binària amb SPSS

    Directory of Open Access Journals (Sweden)

    Vanesa Berlanga-Silvente

    2014-04-01

    Full Text Available Els models de regressió logística són models estadístics en què es desitja conèixer la relació entre: una variable dependent qualitativa dicotòmica (regressió logística binària o binomial i una o més variables explicatives independents, o covariables, ja siguin qualitatives o quantitatives. També és possible una variable dependent qualitativa amb més de dos valors (regressió logística multinomial, encara que en aquesta fitxa ens centrarem en la regressió logística binària. En qualsevol cas, l'equació inicial del model és de tipus exponencial, si bé la seva transformació logarítmica (logit permet el seu ús com una funció lineal. L'objectiu primordial que resol aquesta tècnica és el de modelar com influeixen la probabilitat d'aparició d'un succés, habitualment dicotòmic, la presència o no de diversos factors, i el valor o nivell dels mateixos. Aquesta fitxa sobre la Regressió Logística Binària explica les opcions que té el programa estadístic SPSS (mètodes automàtics "per passos" i la interpretació dels principals resultats.

  3. Evaluating a Federated Medical Search Engine

    Science.gov (United States)

    Belden, J.; Williams, J.; Richardson, B.; Schuster, K.

    2014-01-01

    Summary Background Federated medical search engines are health information systems that provide a single access point to different types of information. Their efficiency as clinical decision support tools has been demonstrated through numerous evaluations. Despite their rigor, very few of these studies report holistic evaluations of medical search engines and even fewer base their evaluations on existing evaluation frameworks. Objectives To evaluate a federated medical search engine, MedSocket, for its potential net benefits in an established clinical setting. Methods This study applied the Human, Organization, and Technology (HOT-fit) evaluation framework in order to evaluate MedSocket. The hierarchical structure of the HOT-factors allowed for identification of a combination of efficiency metrics. Human fit was evaluated through user satisfaction and patterns of system use; technology fit was evaluated through the measurements of time-on-task and the accuracy of the found answers; and organization fit was evaluated from the perspective of system fit to the existing organizational structure. Results Evaluations produced mixed results and suggested several opportunities for system improvement. On average, participants were satisfied with MedSocket searches and confident in the accuracy of retrieved answers. However, MedSocket did not meet participants’ expectations in terms of download speed, access to information, and relevance of the search results. These mixed results made it necessary to conclude that in the case of MedSocket, technology fit had a significant influence on the human and organization fit. Hence, improving technological capabilities of the system is critical before its net benefits can become noticeable. Conclusions The HOT-fit evaluation framework was instrumental in tailoring the methodology for conducting a comprehensive evaluation of the search engine. Such multidimensional evaluation of the search engine resulted in recommendations for

  4. Two-Bin Kanban: Ordering Impact at Navy Medical Center San Diego

    Science.gov (United States)

    2016-06-01

    cost of healthcare . This is done by “focusing on quality, eliminating waste , reducing unwarranted variation, and considering not just the cost of...of the two-bin inventory management system was the supermarket. Food waste is a very high expense for many supermarkets. To mitigate food waste , the...stockpiled medical supplies. Stockpiling supplies is called the “bull whip effect” and it is a wasteful impact of a poorly managed supply system. The

  5. A DNA-based registry for all animal species: the barcode index number (BIN system.

    Directory of Open Access Journals (Sweden)

    Sujeevan Ratnasingham

    Full Text Available Because many animal species are undescribed, and because the identification of known species is often difficult, interim taxonomic nomenclature has often been used in biodiversity analysis. By assigning individuals to presumptive species, called operational taxonomic units (OTUs, these systems speed investigations into the patterning of biodiversity and enable studies that would otherwise be impossible. Although OTUs have conventionally been separated through their morphological divergence, DNA-based delineations are not only feasible, but have important advantages. OTU designation can be automated, data can be readily archived, and results can be easily compared among investigations. This study exploits these attributes to develop a persistent, species-level taxonomic registry for the animal kingdom based on the analysis of patterns of nucleotide variation in the barcode region of the cytochrome c oxidase I (COI gene. It begins by examining the correspondence between groups of specimens identified to a species through prior taxonomic work and those inferred from the analysis of COI sequence variation using one new (RESL and four established (ABGD, CROP, GMYC, jMOTU algorithms. It subsequently describes the implementation, and structural attributes of the Barcode Index Number (BIN system. Aside from a pragmatic role in biodiversity assessments, BINs will aid revisionary taxonomy by flagging possible cases of synonymy, and by collating geographical information, descriptive metadata, and images for specimens that are likely to belong to the same species, even if it is undescribed. More than 274,000 BIN web pages are now available, creating a biodiversity resource that is positioned for rapid growth.

  6. CAZymes Analysis Toolkit (CAT): web service for searching and analyzing carbohydrate-active enzymes in a newly sequenced organism using CAZy database.

    Science.gov (United States)

    Park, Byung H; Karpinets, Tatiana V; Syed, Mustafa H; Leuze, Michael R; Uberbacher, Edward C

    2010-12-01

    The Carbohydrate-Active Enzyme (CAZy) database provides a rich set of manually annotated enzymes that degrade, modify, or create glycosidic bonds. Despite rich and invaluable information stored in the database, software tools utilizing this information for annotation of newly sequenced genomes by CAZy families are limited. We have employed two annotation approaches to fill the gap between manually curated high-quality protein sequences collected in the CAZy database and the growing number of other protein sequences produced by genome or metagenome sequencing projects. The first approach is based on a similarity search against the entire nonredundant sequences of the CAZy database. The second approach performs annotation using links or correspondences between the CAZy families and protein family domains. The links were discovered using the association rule learning algorithm applied to sequences from the CAZy database. The approaches complement each other and in combination achieved high specificity and sensitivity when cross-evaluated with the manually curated genomes of Clostridium thermocellum ATCC 27405 and Saccharophagus degradans 2-40. The capability of the proposed framework to predict the function of unknown protein domains and of hypothetical proteins in the genome of Neurospora crassa is demonstrated. The framework is implemented as a Web service, the CAZymes Analysis Toolkit, and is available at http://cricket.ornl.gov/cgi-bin/cat.cgi.

  7. A Framework for Integrating Oceanographic Data Repositories

    Science.gov (United States)

    Rozell, E.; Maffei, A. R.; Beaulieu, S. E.; Fox, P. A.

    2010-12-01

    Oceanographic research covers a broad range of science domains and requires a tremendous amount of cross-disciplinary collaboration. Advances in cyberinfrastructure are making it easier to share data across disciplines through the use of web services and community vocabularies. Best practices in the design of web services and vocabularies to support interoperability amongst science data repositories are only starting to emerge. Strategic design decisions in these areas are crucial to the creation of end-user data and application integration tools. We present S2S, a novel framework for deploying customizable user interfaces to support the search and analysis of data from multiple repositories. Our research methods follow the Semantic Web methodology and technology development process developed by Fox et al. This methodology stresses the importance of close scientist-technologist interactions when developing scientific use cases, keeping the project well scoped and ensuring the result meets a real scientific need. The S2S framework motivates the development of standardized web services with well-described parameters, as well as the integration of existing web services and applications in the search and analysis of data. S2S also encourages the use and development of community vocabularies and ontologies to support federated search and reduce the amount of domain expertise required in the data discovery process. S2S utilizes the Web Ontology Language (OWL) to describe the components of the framework, including web service parameters, and OpenSearch as a standard description for web services, particularly search services for oceanographic data repositories. We have created search services for an oceanographic metadata database, a large set of quality-controlled ocean profile measurements, and a biogeographic search service. S2S provides an application programming interface (API) that can be used to generate custom user interfaces, supporting data and application

  8. Characterising dark matter searches at colliders and direct detection experiments: Vector mediators

    International Nuclear Information System (INIS)

    Buchmueller, Oliver; Dolan, Matthew J.; Malik, Sarah A.; McCabe, Christopher

    2015-01-01

    We introduce a Minimal Simplified Dark Matter (MSDM) framework to quantitatively characterise dark matter (DM) searches at the LHC. We study two MSDM models where the DM is a Dirac fermion which interacts with a vector and axial-vector mediator. The models are characterised by four parameters: m DM , M med, g DM and g q , the DM and mediator masses, and the mediator couplings to DM and quarks respectively. The MSDM models accurately capture the full event kinematics, and the dependence on all masses and couplings can be systematically studied. The interpretation of mono-jet searches in this framework can be used to establish an equal-footing comparison with direct detection experiments. For theories with a vector mediator, LHC mono-jet searches possess better sensitivity than direct detection searches for light DM masses (≲5 GeV). For axial-vector mediators, LHC and direct detection searches generally probe orthogonal directions in the parameter space. We explore the projected limits of these searches from the ultimate reach of the LHC and multi-ton xenon direct detection experiments, and find that the complementarity of the searches remains. In conclusion, we provide a comparison of limits in the MSDM and effective field theory (EFT) frameworks to highlight the deficiencies of the EFT framework, particularly when exploring the complementarity of mono-jet and direct detection searches

  9. Genetic patterns in European Geometrid Moths revealed by the Barcode Index Number (BIN) System

    NARCIS (Netherlands)

    Hausmann, A.; Godfray, H.C.J.; Huemer, J.; Mutane, M.; Rougerie, R.; Nieukerken, van E.J.; Ratnasingham, S.; Hebert, P.D.N.

    2013-01-01

    Background: The geometrid moths of Europe are one of the best investigated insect groups in traditional taxonomy making them an ideal model group to test the accuracy of the Barcode Index Number (BIN) system of BOLD (Barcode of Life Datasystems), a method that supports automated, rapid species

  10. Effects of Outside Air Temperature on Movement of Phosphine Gas in Concrete Elevator Bins

    Science.gov (United States)

    Studies that measured the movement and concentration of phosphine gas in upright concrete bins over time indicated that fumigant movement was dictated by air currents, which in turn, were a function of the difference between the average grain temperature and the average outside air temperature durin...

  11. Framework of outcome measures recommended for use in the evaluation of childhood obesity treatment interventions: the CoOR framework.

    Science.gov (United States)

    Bryant, M; Ashton, L; Nixon, J; Jebb, S; Wright, J; Roberts, K; Brown, J

    2014-12-01

    Consensus is lacking in determining appropriate outcome measures for assessment of childhood obesity treatments. Inconsistency in the use and reporting of such measures impedes comparisons between treatments and limits consideration of effectiveness. This study aimed to produce a framework of recommended outcome measures: the Childhood obesity treatment evaluation Outcomes Review (CoOR) framework. A systematic review including two searches was conducted to identify (1) existing trial outcome measures and (2) manuscripts describing development/evaluation of outcome measures. Outcomes included anthropometry, diet, eating behaviours, physical activity, sedentary time/behaviour, fitness, physiology, environment, psychological well-being and health-related quality of life. Eligible measures were appraised by the internal team using a system developed from international guidelines, followed by appraisal from national external expert collaborators. A total of 25,486 papers were identified through both searches. Eligible search 1 trial papers cited 417 additional papers linked to outcome measures, of which 56 were eligible. A further 297 outcome development/evaluation papers met eligibility criteria from search 2. Combined, these described 191 outcome measures. After internal and external appraisal, 52 measures across 10 outcomes were recommended for inclusion in the CoOR framework. Application of the CoOR framework will ensure greater consistency in choosing robust outcome measures that are appropriate to population characteristics. © 2014 The Authors. Pediatric Obesity © 2014 International Association for the Study of Obesity.

  12. A Bayesian framework for cosmic string searches in CMB maps

    Energy Technology Data Exchange (ETDEWEB)

    Ciuca, Razvan; Hernández, Oscar F., E-mail: razvan.ciuca@mail.mcgill.ca, E-mail: oscarh@physics.mcgill.ca [Department of Physics, McGill University, 3600 rue University, Montréal, QC, H3A 2T8 (Canada)

    2017-08-01

    There exists various proposals to detect cosmic strings from Cosmic Microwave Background (CMB) or 21 cm temperature maps. Current proposals do not aim to find the location of strings on sky maps, all of these approaches can be thought of as a statistic on a sky map. We propose a Bayesian interpretation of cosmic string detection and within that framework, we derive a connection between estimates of cosmic string locations and cosmic string tension G μ. We use this Bayesian framework to develop a machine learning framework for detecting strings from sky maps and outline how to implement this framework with neural networks. The neural network we trained was able to detect and locate cosmic strings on noiseless CMB temperature map down to a string tension of G μ=5 ×10{sup −9} and when analyzing a CMB temperature map that does not contain strings, the neural network gives a 0.95 probability that G μ≤2.3×10{sup −9}.

  13. Spatial Analysis of the Solid Waste Bins in the Sectors of the City of Mosul "Environmental Study in Geographic Information Systems"

    Directory of Open Access Journals (Sweden)

    Zainab A. Khalaf

    2018-01-01

    Full Text Available An experimental study on a passive solar distiller in the Tikrit city on (latitude line"34 36o The problem of solid waste in Mosul city is one of the most important daily problems that faces the municipal and other institutions, because it consists eight sectors and those of varied in the people preparation, economic conditions and area, This study aimed to identify the spatial variation of solid waste as well as the geographical distribution of bins numbers and spatial analysis using geographic information systems. The study produced many maps of the bins number distribution geographically using buffer tools that used to determine the area served by a single bin, as well as the maps of the spatial analysis by Theissen polygons and IDW methods. The study results proved the efficiency of IDW compared to Theissen polygons method, because the analysis by polygons Theissen methods show only  the capacity and efficiency of the bin to accommodate the solid waste at the same location, as well as of the generality and comprehensiveness at the area expense in the spatial description process unlike the first type. DOI: http://dx.doi.org/10.25130/tjes.24.2017.23

  14. Motivation in pediatric motor rehabilitation: A systematic search of the literature using the self-determination theory as a conceptual framework.

    Science.gov (United States)

    Meyns, Pieter; Roman de Mettelinge, Tine; van der Spank, Judith; Coussens, Marieke; Van Waelvelde, Hilde

    2017-03-09

    Motivation is suggested as an important factor in pediatric motor rehabilitation. Therefore, we reviewed the existing evidence of (motivational) motor rehabilitation paradigms, and how motivation influences rehabilitation outcome using self-determination theory as conceptual framework. PubMed and Web-of-Science databases were systematically searched until June 2015. Data were independently extracted and critiqued for quality by three authors. Studies reporting motivational aspects were included. Most studies examined new technology (e.g., virtual reality [VR]). Out of 479 records, three RCT, six case-control, and six non-comparative studies were included with mixed quality. Motivation was rarely reported. Training individualization to the child's capabilities with more variety seemed promising to increase motivation. Motivation increased when the exercises seemed helpful for daily activities. Motivation in pediatric rehabilitation should be comprehensively assessed within a theoretical framework as there are indications that motivated children have better rehabilitation outcomes, depending on the aspect of motivation.

  15. BinAligner: a heuristic method to align biological networks.

    Science.gov (United States)

    Yang, Jialiang; Li, Jun; Grünewald, Stefan; Wan, Xiu-Feng

    2013-01-01

    The advances in high throughput omics technologies have made it possible to characterize molecular interactions within and across various species. Alignments and comparison of molecular networks across species will help detect orthologs and conserved functional modules and provide insights on the evolutionary relationships of the compared species. However, such analyses are not trivial due to the complexity of network and high computational cost. Here we develop a mixture of global and local algorithm, BinAligner, for network alignments. Based on the hypotheses that the similarity between two vertices across networks would be context dependent and that the information from the edges and the structures of subnetworks can be more informative than vertices alone, two scoring schema, 1-neighborhood subnetwork and graphlet, were introduced to derive the scoring matrices between networks, besides the commonly used scoring scheme from vertices. Then the alignment problem is formulated as an assignment problem, which is solved by the combinatorial optimization algorithm, such as the Hungarian method. The proposed algorithm was applied and validated in aligning the protein-protein interaction network of Kaposi's sarcoma associated herpesvirus (KSHV) and that of varicella zoster virus (VZV). Interestingly, we identified several putative functional orthologous proteins with similar functions but very low sequence similarity between the two viruses. For example, KSHV open reading frame 56 (ORF56) and VZV ORF55 are helicase-primase subunits with sequence identity 14.6%, and KSHV ORF75 and VZV ORF44 are tegument proteins with sequence identity 15.3%. These functional pairs can not be identified if one restricts the alignment into orthologous protein pairs. In addition, BinAligner identified a conserved pathway between two viruses, which consists of 7 orthologous protein pairs and these proteins are connected by conserved links. This pathway might be crucial for virus packing and

  16. Generalized Information Theory Meets Human Cognition: Introducing a Unified Framework to Model Uncertainty and Information Search.

    Science.gov (United States)

    Crupi, Vincenzo; Nelson, Jonathan D; Meder, Björn; Cevolani, Gustavo; Tentori, Katya

    2018-06-17

    Searching for information is critical in many situations. In medicine, for instance, careful choice of a diagnostic test can help narrow down the range of plausible diseases that the patient might have. In a probabilistic framework, test selection is often modeled by assuming that people's goal is to reduce uncertainty about possible states of the world. In cognitive science, psychology, and medical decision making, Shannon entropy is the most prominent and most widely used model to formalize probabilistic uncertainty and the reduction thereof. However, a variety of alternative entropy metrics (Hartley, Quadratic, Tsallis, Rényi, and more) are popular in the social and the natural sciences, computer science, and philosophy of science. Particular entropy measures have been predominant in particular research areas, and it is often an open issue whether these divergences emerge from different theoretical and practical goals or are merely due to historical accident. Cutting across disciplinary boundaries, we show that several entropy and entropy reduction measures arise as special cases in a unified formalism, the Sharma-Mittal framework. Using mathematical results, computer simulations, and analyses of published behavioral data, we discuss four key questions: How do various entropy models relate to each other? What insights can be obtained by considering diverse entropy models within a unified framework? What is the psychological plausibility of different entropy models? What new questions and insights for research on human information acquisition follow? Our work provides several new pathways for theoretical and empirical research, reconciling apparently conflicting approaches and empirical findings within a comprehensive and unified information-theoretic formalism. Copyright © 2018 Cognitive Science Society, Inc.

  17. The Effectiveness of the Curriculum Biography of the Prophet in the Development of Social Intelligence Skills of Al-Hussein Bin Talal University Students

    Science.gov (United States)

    Al-Khateeb, Omar; Alrub, Mohammad Abo

    2015-01-01

    This study aimed to find out how the effectiveness of the curriculum biography of the Prophet in the development of social intelligence skills of Al-Hussein Bin Talal University students and the study sample consisted of 365 students from Al-Hussein Bin Talal University for the first semester 2014-2015 students were selected in accessible manner.…

  18. A Search Model of Discouragement

    DEFF Research Database (Denmark)

    Rosholm, Michael; Toomet, Ott

    Discouragement is a process occurring during an unemployment spell. As the spell prolongs, an individual gradually realises that the returns to search can no longer outweigh search costs, and hence she may eventually leave the labour force. This is analysed theoretically in a framework...... of unemployed search. We construct a search model, which is stationary from the point of view of the individual, but which has nonstationary features. Namely, the unemployed worker is occasionally hit by shocks leading to a decline in job offer arrival rates. These shocks can be due to stigmatisation...... or to psychological consequences of unemployement affecting search effectiveness. This model enables us to analyse the issue of discouragement, as the returns to search will gradually decline. Even so, the model is actually stationary from the point of view of the individual, which implies that many interesting...

  19. SIRW: A web server for the Simple Indexing and Retrieval System that combines sequence motif searches with keyword searches.

    Science.gov (United States)

    Ramu, Chenna

    2003-07-01

    SIRW (http://sirw.embl.de/) is a World Wide Web interface to the Simple Indexing and Retrieval System (SIR) that is capable of parsing and indexing various flat file databases. In addition it provides a framework for doing sequence analysis (e.g. motif pattern searches) for selected biological sequences through keyword search. SIRW is an ideal tool for the bioinformatics community for searching as well as analyzing biological sequences of interest.

  20. Development of Seismic Demand for Chang-Bin Offshore Wind Farm in Taiwan Strait

    Directory of Open Access Journals (Sweden)

    Yu-Kai Wang

    2016-12-01

    Full Text Available Taiwan is located on the Pacific seismic belt, and the soil conditions of Taiwan’s offshore wind farms are softer than those in Europe. To ensure safety and stability of the offshore wind turbine supporting structures, it is important to assess the offshore wind farms seismic forces reasonably. In this paper, the relevant seismic and geological data are obtained for Chang-Bin offshore wind farm in Taiwan Strait, the probabilistic seismic hazard analysis (PSHA is carried out, and the first uniform hazard response spectrum for Chang-Bin offshore wind farm is achieved. Compared with existing design response spectrum in the local regulation, this site-specific seismic hazard analysis has influence on the seismic force considered in the design of supporting structures and therefore affects the cost of the supporting structures. The results show that a site-specific seismic hazard analysis is required for high seismic area. The paper highlights the importance of seismic hazard analysis to assess the offshore wind farms seismic forces. The follow-up recommendations and research directions are given for Taiwan’s offshore wind turbine supporting structures under seismic force considerations.

  1. Parallel content-based sub-image retrieval using hierarchical searching.

    Science.gov (United States)

    Yang, Lin; Qi, Xin; Xing, Fuyong; Kurc, Tahsin; Saltz, Joel; Foran, David J

    2014-04-01

    The capacity to systematically search through large image collections and ensembles and detect regions exhibiting similar morphological characteristics is central to pathology diagnosis. Unfortunately, the primary methods used to search digitized, whole-slide histopathology specimens are slow and prone to inter- and intra-observer variability. The central objective of this research was to design, develop, and evaluate a content-based image retrieval system to assist doctors for quick and reliable content-based comparative search of similar prostate image patches. Given a representative image patch (sub-image), the algorithm will return a ranked ensemble of image patches throughout the entire whole-slide histology section which exhibits the most similar morphologic characteristics. This is accomplished by first performing hierarchical searching based on a newly developed hierarchical annular histogram (HAH). The set of candidates is then further refined in the second stage of processing by computing a color histogram from eight equally divided segments within each square annular bin defined in the original HAH. A demand-driven master-worker parallelization approach is employed to speed up the searching procedure. Using this strategy, the query patch is broadcasted to all worker processes. Each worker process is dynamically assigned an image by the master process to search for and return a ranked list of similar patches in the image. The algorithm was tested using digitized hematoxylin and eosin (H&E) stained prostate cancer specimens. We have achieved an excellent image retrieval performance. The recall rate within the first 40 rank retrieved image patches is ∼90%. Both the testing data and source code can be downloaded from http://pleiad.umdnj.edu/CBII/Bioinformatics/.

  2. Optimal search behavior and classic foraging theory

    International Nuclear Information System (INIS)

    Bartumeus, F; Catalan, J

    2009-01-01

    Random walk methods and diffusion theory pervaded ecological sciences as methods to analyze and describe animal movement. Consequently, statistical physics was mostly seen as a toolbox rather than as a conceptual framework that could contribute to theory on evolutionary biology and ecology. However, the existence of mechanistic relationships and feedbacks between behavioral processes and statistical patterns of movement suggests that, beyond movement quantification, statistical physics may prove to be an adequate framework to understand animal behavior across scales from an ecological and evolutionary perspective. Recently developed random search theory has served to critically re-evaluate classic ecological questions on animal foraging. For instance, during the last few years, there has been a growing debate on whether search behavior can include traits that improve success by optimizing random (stochastic) searches. Here, we stress the need to bring together the general encounter problem within foraging theory, as a mean for making progress in the biological understanding of random searching. By sketching the assumptions of optimal foraging theory (OFT) and by summarizing recent results on random search strategies, we pinpoint ways to extend classic OFT, and integrate the study of search strategies and its main results into the more general theory of optimal foraging.

  3. Likelihood functions for the analysis of single-molecule binned photon sequences

    Energy Technology Data Exchange (ETDEWEB)

    Gopich, Irina V., E-mail: irinag@niddk.nih.gov [Laboratory of Chemical Physics, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Bethesda, MD 20892 (United States)

    2012-03-02

    Graphical abstract: Folding of a protein with attached fluorescent dyes, the underlying conformational trajectory of interest, and the observed binned photon trajectory. Highlights: Black-Right-Pointing-Pointer A sequence of photon counts can be analyzed using a likelihood function. Black-Right-Pointing-Pointer The exact likelihood function for a two-state kinetic model is provided. Black-Right-Pointing-Pointer Several approximations are considered for an arbitrary kinetic model. Black-Right-Pointing-Pointer Improved likelihood functions are obtained to treat sequences of FRET efficiencies. - Abstract: We consider the analysis of a class of experiments in which the number of photons in consecutive time intervals is recorded. Sequence of photon counts or, alternatively, of FRET efficiencies can be studied using likelihood-based methods. For a kinetic model of the conformational dynamics and state-dependent Poisson photon statistics, the formalism to calculate the exact likelihood that this model describes such sequences of photons or FRET efficiencies is developed. Explicit analytic expressions for the likelihood function for a two-state kinetic model are provided. The important special case when conformational dynamics are so slow that at most a single transition occurs in a time bin is considered. By making a series of approximations, we eventually recover the likelihood function used in hidden Markov models. In this way, not only is insight gained into the range of validity of this procedure, but also an improved likelihood function can be obtained.

  4. Towards an evaluation framework for Laboratory Information Systems.

    Science.gov (United States)

    Yusof, Maryati M; Arifin, Azila

    Laboratory testing and reporting are error-prone and redundant due to repeated, unnecessary requests and delayed or missed reactions to laboratory reports. Occurring errors may negatively affect the patient treatment process and clinical decision making. Evaluation on laboratory testing and Laboratory Information System (LIS) may explain the root cause to improve the testing process and enhance LIS in supporting the process. This paper discusses a new evaluation framework for LIS that encompasses the laboratory testing cycle and the socio-technical part of LIS. Literature review on discourses, dimensions and evaluation methods of laboratory testing and LIS. A critical appraisal of the Total Testing Process (TTP) and the human, organization, technology-fit factors (HOT-fit) evaluation frameworks was undertaken in order to identify error incident, its contributing factors and preventive action pertinent to laboratory testing process and LIS. A new evaluation framework for LIS using a comprehensive and socio-technical approach is outlined. Positive relationship between laboratory and clinical staff resulted in a smooth laboratory testing process, reduced errors and increased process efficiency whilst effective use of LIS streamlined the testing processes. The TTP-LIS framework could serve as an assessment as well as a problem-solving tool for the laboratory testing process and system. Copyright © 2016 King Saud Bin Abdulaziz University for Health Sciences. Published by Elsevier Ltd. All rights reserved.

  5. Closing the scale gap between land surface parameterizations and GCMs with a new scheme, SiB3-Bins: SOIL MOISTURE SCALE GAP

    International Nuclear Information System (INIS)

    Baker, I. T.; Sellers, P. J.; Denning, A. S.; Medina, I.; Kraus, P.

    2017-01-01

    The interaction of land with the atmosphere is sensitive to soil moisture (W). Evapotranspiration (ET) reacts to soil moisture in a nonlinear way, f(W), as soils dry from saturation to wilt point. This nonlinear behavior and the fact that soil moisture varies on scales as small as 1–10 m in nature, while numerical general circulation models (GCMs) have grid cell sizes on the order of 1 to 100s of kilometers, makes the calculation of grid cell-average ET problematic. It is impractical to simulate the land in GCMs on the small scales seen in nature, so techniques have been developed to represent subgrid scale heterogeneity, including: (1) statistical-dynamical representations of grid subelements of varying wetness, (2) relaxation of f(W), (3) moderating f(W) with approximations of catchment hydrology, (4) “tiling” the landscape into vegetation types, and (5) hyperresolution. Here we present an alternative method for representing subgrid variability in W, one proven in a conceptual framework where landscape-scale W is represented as a series of “Bins” of increasing wetness from dry to saturated. The grid cell-level f(W) is defined by the integral of the fractional area of the wetness bins and the value of f(W) associated with each. This approach accounts for the spatiotemporal dynamics of W. We implemented this approach in the SiB3 land surface parameterization and then evaluated its performance against a control, which assumes a horizontally uniform field of W. We demonstrate that the Bins method, with a physical basis, attenuates unrealistic jumps in model state and ET seen in the control runs.

  6. Is searching full text more effective than searching abstracts?

    Science.gov (United States)

    Lin, Jimmy

    2009-02-03

    With the growing availability of full-text articles online, scientists and other consumers of the life sciences literature now have the ability to go beyond searching bibliographic records (title, abstract, metadata) to directly access full-text content. Motivated by this emerging trend, I posed the following question: is searching full text more effective than searching abstracts? This question is answered by comparing text retrieval algorithms on MEDLINE abstracts, full-text articles, and spans (paragraphs) within full-text articles using data from the TREC 2007 genomics track evaluation. Two retrieval models are examined: bm25 and the ranking algorithm implemented in the open-source Lucene search engine. Experiments show that treating an entire article as an indexing unit does not consistently yield higher effectiveness compared to abstract-only search. However, retrieval based on spans, or paragraphs-sized segments of full-text articles, consistently outperforms abstract-only search. Results suggest that highest overall effectiveness may be achieved by combining evidence from spans and full articles. Users searching full text are more likely to find relevant articles than searching only abstracts. This finding affirms the value of full text collections for text retrieval and provides a starting point for future work in exploring algorithms that take advantage of rapidly-growing digital archives. Experimental results also highlight the need to develop distributed text retrieval algorithms, since full-text articles are significantly longer than abstracts and may require the computational resources of multiple machines in a cluster. The MapReduce programming model provides a convenient framework for organizing such computations.

  7. Is searching full text more effective than searching abstracts?

    Directory of Open Access Journals (Sweden)

    Lin Jimmy

    2009-02-01

    Full Text Available Abstract Background With the growing availability of full-text articles online, scientists and other consumers of the life sciences literature now have the ability to go beyond searching bibliographic records (title, abstract, metadata to directly access full-text content. Motivated by this emerging trend, I posed the following question: is searching full text more effective than searching abstracts? This question is answered by comparing text retrieval algorithms on MEDLINE® abstracts, full-text articles, and spans (paragraphs within full-text articles using data from the TREC 2007 genomics track evaluation. Two retrieval models are examined: bm25 and the ranking algorithm implemented in the open-source Lucene search engine. Results Experiments show that treating an entire article as an indexing unit does not consistently yield higher effectiveness compared to abstract-only search. However, retrieval based on spans, or paragraphs-sized segments of full-text articles, consistently outperforms abstract-only search. Results suggest that highest overall effectiveness may be achieved by combining evidence from spans and full articles. Conclusion Users searching full text are more likely to find relevant articles than searching only abstracts. This finding affirms the value of full text collections for text retrieval and provides a starting point for future work in exploring algorithms that take advantage of rapidly-growing digital archives. Experimental results also highlight the need to develop distributed text retrieval algorithms, since full-text articles are significantly longer than abstracts and may require the computational resources of multiple machines in a cluster. The MapReduce programming model provides a convenient framework for organizing such computations.

  8. SU-F-303-11: Implementation and Applications of Rapid, SIFT-Based Cine MR Image Binning and Region Tracking

    Energy Technology Data Exchange (ETDEWEB)

    Mazur, T; Wang, Y; Fischer-Valuck, B; Acharya, S; Kashani, R; Li, H; Yang, D; Zoberi, I; Thomas, M; Mutic, S; Li, H [Washington University School of Medicine, St. Louis, MO (United States)

    2015-06-15

    Purpose: To develop a novel and rapid, SIFT-based algorithm for assessing feature motion on cine MR images acquired during MRI-guided radiotherapy treatments. In particular, we apply SIFT descriptors toward both partitioning cine images into respiratory states and tracking regions across frames. Methods: Among a training set of images acquired during a fraction, we densely assign SIFT descriptors to pixels within the images. We cluster these descriptors across all frames in order to produce a dictionary of trackable features. Associating the best-matching descriptors at every frame among the training images to these features, we construct motion traces for the features. We use these traces to define respiratory bins for sorting images in order to facilitate robust pixel-by-pixel tracking. Instead of applying conventional methods for identifying pixel correspondences across frames we utilize a recently-developed algorithm that derives correspondences via a matching objective for SIFT descriptors. Results: We apply these methods to a collection of lung, abdominal, and breast patients. We evaluate the procedure for respiratory binning using target sites exhibiting high-amplitude motion among 20 lung and abdominal patients. In particular, we investigate whether these methods yield minimal variation between images within a bin by perturbing the resulting image distributions among bins. Moreover, we compare the motion between averaged images across respiratory states to 4DCT data for these patients. We evaluate the algorithm for obtaining pixel correspondences between frames by tracking contours among a set of breast patients. As an initial case, we track easily-identifiable edges of lumpectomy cavities that show minimal motion over treatment. Conclusions: These SIFT-based methods reliably extract motion information from cine MR images acquired during patient treatments. While we performed our analysis retrospectively, the algorithm lends itself to prospective motion

  9. Longitudinal Acceleration Tests of Overhead Luggage Bins and Auxiliary Fuel Tank in a Transport Airplane Airframe Section

    National Research Council Canada - National Science Library

    McGuire, Robert

    1999-01-01

    This report contains the description and test results of overhead stowage bin calibrations and longitudinal impact testing of a 10-foot transport airframe section conducted at the Transportation Research Center Inc. (TRC...

  10. Low-Light Image Enhancement Using Adaptive Digital Pixel Binning

    Directory of Open Access Journals (Sweden)

    Yoonjong Yoo

    2015-06-01

    Full Text Available This paper presents an image enhancement algorithm for low-light scenes in an environment with insufficient illumination. Simple amplification of intensity exhibits various undesired artifacts: noise amplification, intensity saturation, and loss of resolution. In order to enhance low-light images without undesired artifacts, a novel digital binning algorithm is proposed that considers brightness, context, noise level, and anti-saturation of a local region in the image. The proposed algorithm does not require any modification of the image sensor or additional frame-memory; it needs only two line-memories in the image signal processor (ISP. Since the proposed algorithm does not use an iterative computation, it can be easily embedded in an existing digital camera ISP pipeline containing a high-resolution image sensor.

  11. Research and Development of a New Waste Collection Bin to Facilitate Education in Plastic Recycling

    Science.gov (United States)

    Chow, Cheuk-fai; So, Wing-Mui Winnie; Cheung, Tsz-Yan

    2016-01-01

    Plastic recycling has been an alternative method for solid waste management apart from landfill and incineration. However, recycling quality is affected when all plastics are discarded into a single recycling bin that increases cross contaminations and operation cost to the recycling industry. Following the engineering design process, a new…

  12. Time-bin entangled photon pairs from spontaneous parametric down-conversion pumped by a cw multi-mode diode laser.

    Science.gov (United States)

    Kwon, Osung; Park, Kwang-Kyoon; Ra, Young-Sik; Kim, Yong-Su; Kim, Yoon-Ho

    2013-10-21

    Generation of time-bin entangled photon pairs requires the use of the Franson interferometer which consists of two spatially separated unbalanced Mach-Zehnder interferometers through which the signal and idler photons from spontaneous parametric down-conversion (SPDC) are made to transmit individually. There have been two SPDC pumping regimes where the scheme works: the narrowband regime and the double-pulse regime. In the narrowband regime, the SPDC process is pumped by a narrowband cw laser with the coherence length much longer than the path length difference of the Franson interferometer. In the double-pulse regime, the longitudinal separation between the pulse pair is made equal to the path length difference of the Franson interferometer. In this paper, we propose another regime by which the generation of time-bin entanglement is possible and demonstrate the scheme experimentally. In our scheme, differently from the previous approaches, the SPDC process is pumped by a cw multi-mode (i.e., short coherence length) laser and makes use of the coherence revival property of such a laser. The high-visibility two-photon Franson interference demonstrates clearly that high-quality time-bin entanglement source can be developed using inexpensive cw multi-mode diode lasers for various quantum communication applications.

  13. Backtracking search algorithm in CVRP models for efficient solid waste collection and route optimization.

    Science.gov (United States)

    Akhtar, Mahmuda; Hannan, M A; Begum, R A; Basri, Hassan; Scavino, Edgar

    2017-03-01

    Waste collection is an important part of waste management that involves different issues, including environmental, economic, and social, among others. Waste collection optimization can reduce the waste collection budget and environmental emissions by reducing the collection route distance. This paper presents a modified Backtracking Search Algorithm (BSA) in capacitated vehicle routing problem (CVRP) models with the smart bin concept to find the best optimized waste collection route solutions. The objective function minimizes the sum of the waste collection route distances. The study introduces the concept of the threshold waste level (TWL) of waste bins to reduce the number of bins to be emptied by finding an optimal range, thus minimizing the distance. A scheduling model is also introduced to compare the feasibility of the proposed model with that of the conventional collection system in terms of travel distance, collected waste, fuel consumption, fuel cost, efficiency and CO 2 emission. The optimal TWL was found to be between 70% and 75% of the fill level of waste collection nodes and had the maximum tightness value for different problem cases. The obtained results for four days show a 36.80% distance reduction for 91.40% of the total waste collection, which eventually increases the average waste collection efficiency by 36.78% and reduces the fuel consumption, fuel cost and CO 2 emission by 50%, 47.77% and 44.68%, respectively. Thus, the proposed optimization model can be considered a viable tool for optimizing waste collection routes to reduce economic costs and environmental impacts. Copyright © 2017 Elsevier Ltd. All rights reserved.

  14. Infodemiology and infoveillance: framework for an emerging set of public health informatics methods to analyze search, communication and publication behavior on the Internet.

    Science.gov (United States)

    Eysenbach, Gunther

    2009-03-27

    Infodemiology can be defined as the science of distribution and determinants of information in an electronic medium, specifically the Internet, or in a population, with the ultimate aim to inform public health and public policy. Infodemiology data can be collected and analyzed in near real time. Examples for infodemiology applications include the analysis of queries from Internet search engines to predict disease outbreaks (eg. influenza), monitoring peoples' status updates on microblogs such as Twitter for syndromic surveillance, detecting and quantifying disparities in health information availability, identifying and monitoring of public health relevant publications on the Internet (eg. anti-vaccination sites, but also news articles or expert-curated outbreak reports), automated tools to measure information diffusion and knowledge translation, and tracking the effectiveness of health marketing campaigns. Moreover, analyzing how people search and navigate the Internet for health-related information, as well as how they communicate and share this information, can provide valuable insights into health-related behavior of populations. Seven years after the infodemiology concept was first introduced, this paper revisits the emerging fields of infodemiology and infoveillance and proposes an expanded framework, introducing some basic metrics such as information prevalence, concept occurrence ratios, and information incidence. The framework distinguishes supply-based applications (analyzing what is being published on the Internet, eg. on Web sites, newsgroups, blogs, microblogs and social media) from demand-based methods (search and navigation behavior), and further distinguishes passive from active infoveillance methods. Infodemiology metrics follow population health relevant events or predict them. Thus, these metrics and methods are potentially useful for public health practice and research, and should be further developed and standardized.

  15. Coupling spectral-bin cloud microphysics with the MOSAIC aerosol model in WRF-Chem: Methodology and results for marine stratocumulus clouds

    Science.gov (United States)

    Gao, Wenhua; Fan, Jiwen; Easter, R. C.; Yang, Qing; Zhao, Chun; Ghan, Steven J.

    2016-09-01

    Aerosol-cloud interaction processes can be represented more physically with bin cloud microphysics relative to bulk microphysical parameterizations. However, due to computational power limitations in the past, bin cloud microphysics was often run with very simple aerosol treatments. The purpose of this study is to represent better aerosol-cloud interaction processes in the Chemistry version of Weather Research and Forecast model (WRF-Chem) at convection-permitting scales by coupling spectral-bin cloud microphysics (SBM) with the MOSAIC sectional aerosol model. A flexible interface is built that exchanges cloud and aerosol information between them. The interface contains a new bin aerosol activation approach, which replaces the treatments in the original SBM. It also includes the modified aerosol resuspension and in-cloud wet removal processes with the droplet loss tendencies and precipitation fluxes from SBM. The newly coupled system is evaluated for two marine stratocumulus cases over the Southeast Pacific Ocean with either a simplified aerosol setup or full-chemistry. We compare the aerosol activation process in the newly coupled SBM-MOSAIC against the SBM simulation without chemistry using a simplified aerosol setup, and the results show consistent activation rates. A longer time simulation reinforces that aerosol resuspension through cloud drop evaporation plays an important role in replenishing aerosols and impacts cloud and precipitation in marine stratocumulus clouds. Evaluation of the coupled SBM-MOSAIC with full-chemistry using aircraft measurements suggests that the new model works realistically for the marine stratocumulus clouds, and improves the simulation of cloud microphysical properties compared to a simulation using MOSAIC coupled with the Morrison two-moment microphysics.

  16. In search of a governance framework for responsible research and innovation

    NARCIS (Netherlands)

    Walhout, Bart; Walhout, A.M.; Kuhlmann, Stefan

    2013-01-01

    The European research project Res-AGorA aims to develop a governance framework for Responsible Research and Innovation (RRI). This paper presents the analysis behind our approach. While the various existing RRI governance arrangements do call for a comprehensive framework, the heterogeneity of R&I

  17. The Islamic Ethics in the poetry of ‘Abdullah bin al-Mubarak (Arabic

    Directory of Open Access Journals (Sweden)

    Dr. Muhammad Ismail Bin Abdul Salam

    2017-01-01

    Full Text Available Abstract ‘Abdullah bin al-Mubark was born in Marw’ one of the prime cities in Khurasan, (nowadays in the surroundings of Afghanistan and Central Asia, in the year 118 AH. In addition to his many talents, achievements and abilities, ‘Abdullah bin al-Mubarak was also gifted in literacy, particularly in the art of poetry. He held an eloquent tongue which was recognized by all who conversed with him and his language displayed the nature of someone who had been taught well. Most of the poetry which has been recorded from him is actually his advice to others, whether they were close friends or high-ranking Caliphs and Rulers. The topics spoken of concerned the common issues which had arisen in his time (e.g. matters pertaining to theology, politics, the worldview, the community etc and as always, they contained much wisdom and hence the books of history have sealed them and recorded them. This research article discussed Biography of Abdullah ibn Al Mubarak, The Islamic Ethics in his poetry,\tImpact of Rhetoric on his poetry with special concentration on the four kinds i.e. citation, impact of Quranic words, Quranic pictorial and Quranic style on his poetry.

  18. A new pressure ulcer conceptual framework

    Science.gov (United States)

    Coleman, Susanne; Nixon, Jane; Keen, Justin; Wilson, Lyn; McGinnis, Elizabeth; Dealey, Carol; Stubbs, Nikki; Farrin, Amanda; Dowding, Dawn; Schols, Jos MGA; Cuddigan, Janet; Berlowitz, Dan; Jude, Edward; Vowden, Peter; Schoonhoven, Lisette; Bader, Dan L; Gefen, Amit; Oomens, Cees WJ; Nelson, E Andrea

    2014-01-01

    Aim This paper discusses the critical determinants of pressure ulcer development and proposes a new pressure ulcer conceptual framework. Background Recent work to develop and validate a new evidence-based pressure ulcer risk assessment framework was undertaken. This formed part of a Pressure UlceR Programme Of reSEarch (RP-PG-0407-10056), funded by the National Institute for Health Research. The foundation for the risk assessment component incorporated a systematic review and a consensus study that highlighted the need to propose a new conceptual framework. Design Discussion Paper. Data Sources The new conceptual framework links evidence from biomechanical, physiological and epidemiological evidence, through use of data from a systematic review (search conducted March 2010), a consensus study (conducted December 2010–2011) and an international expert group meeting (conducted December 2011). Implications for Nursing A new pressure ulcer conceptual framework incorporating key physiological and biomechanical components and their impact on internal strains, stresses and damage thresholds is proposed. Direct and key indirect causal factors suggested in a theoretical causal pathway are mapped to the physiological and biomechanical components of the framework. The new proposed conceptual framework provides the basis for understanding the critical determinants of pressure ulcer development and has the potential to influence risk assessment guidance and practice. It could also be used to underpin future research to explore the role of individual risk factors conceptually and operationally. Conclusion By integrating existing knowledge from epidemiological, physiological and biomechanical evidence, a theoretical causal pathway and new conceptual framework are proposed with potential implications for practice and research. PMID:24684197

  19. A new pressure ulcer conceptual framework.

    Science.gov (United States)

    Coleman, Susanne; Nixon, Jane; Keen, Justin; Wilson, Lyn; McGinnis, Elizabeth; Dealey, Carol; Stubbs, Nikki; Farrin, Amanda; Dowding, Dawn; Schols, Jos M G A; Cuddigan, Janet; Berlowitz, Dan; Jude, Edward; Vowden, Peter; Schoonhoven, Lisette; Bader, Dan L; Gefen, Amit; Oomens, Cees W J; Nelson, E Andrea

    2014-10-01

    This paper discusses the critical determinants of pressure ulcer development and proposes a new pressure ulcer conceptual framework. Recent work to develop and validate a new evidence-based pressure ulcer risk assessment framework was undertaken. This formed part of a Pressure UlceR Programme Of reSEarch (RP-PG-0407-10056), funded by the National Institute for Health Research. The foundation for the risk assessment component incorporated a systematic review and a consensus study that highlighted the need to propose a new conceptual framework. Discussion Paper. The new conceptual framework links evidence from biomechanical, physiological and epidemiological evidence, through use of data from a systematic review (search conducted March 2010), a consensus study (conducted December 2010-2011) and an international expert group meeting (conducted December 2011). A new pressure ulcer conceptual framework incorporating key physiological and biomechanical components and their impact on internal strains, stresses and damage thresholds is proposed. Direct and key indirect causal factors suggested in a theoretical causal pathway are mapped to the physiological and biomechanical components of the framework. The new proposed conceptual framework provides the basis for understanding the critical determinants of pressure ulcer development and has the potential to influence risk assessment guidance and practice. It could also be used to underpin future research to explore the role of individual risk factors conceptually and operationally. By integrating existing knowledge from epidemiological, physiological and biomechanical evidence, a theoretical causal pathway and new conceptual framework are proposed with potential implications for practice and research. © 2014 The Authors. Journal of Advanced Nursing Published by John Wiley & Sons Ltd.

  20. Metagenomic binning of a marine sponge microbiome reveals unity in defense but metabolic specialization.

    Science.gov (United States)

    Slaby, Beate M; Hackl, Thomas; Horn, Hannes; Bayer, Kristina; Hentschel, Ute

    2017-11-01

    Marine sponges are ancient metazoans that are populated by distinct and highly diverse microbial communities. In order to obtain deeper insights into the functional gene repertoire of the Mediterranean sponge Aplysina aerophoba, we combined Illumina short-read and PacBio long-read sequencing followed by un-targeted metagenomic binning. We identified a total of 37 high-quality bins representing 11 bacterial phyla and two candidate phyla. Statistical comparison of symbiont genomes with selected reference genomes revealed a significant enrichment of genes related to bacterial defense (restriction-modification systems, toxin-antitoxin systems) as well as genes involved in host colonization and extracellular matrix utilization in sponge symbionts. A within-symbionts genome comparison revealed a nutritional specialization of at least two symbiont guilds, where one appears to metabolize carnitine and the other sulfated polysaccharides, both of which are abundant molecules in the sponge extracellular matrix. A third guild of symbionts may be viewed as nutritional generalists that perform largely the same metabolic pathways but lack such extraordinary numbers of the relevant genes. This study characterizes the genomic repertoire of sponge symbionts at an unprecedented resolution and it provides greater insights into the molecular mechanisms underlying microbial-sponge symbiosis.

  1. Bin packing problem solution through a deterministic weighted finite automaton

    Science.gov (United States)

    Zavala-Díaz, J. C.; Pérez-Ortega, J.; Martínez-Rebollar, A.; Almanza-Ortega, N. N.; Hidalgo-Reyes, M.

    2016-06-01

    In this article the solution of Bin Packing problem of one dimension through a weighted finite automaton is presented. Construction of the automaton and its application to solve three different instances, one synthetic data and two benchmarks are presented: N1C1W1_A.BPP belonging to data set Set_1; and BPP13.BPP belonging to hard28. The optimal solution of synthetic data is obtained. In the first benchmark the solution obtained is one more container than the ideal number of containers and in the second benchmark the solution is two more containers than the ideal solution (approximately 2.5%). The runtime in all three cases was less than one second.

  2. OERScout Technology Framework: A Novel Approach to Open Educational Resources Search

    OpenAIRE

    Ishan Sudeera Abeywardena; Chee Seng Chan; Choy Yoong Tham

    2013-01-01

    The open educational resources (OER) movement has gained momentum in the past few years. With this new drive towards making knowledge open and accessible, a large number of OER repositories have been established and made available online throughout the world. However, the inability of existing search engines such as Google, Yahoo!, and Bing to effectively search for useful OER which are of acceptable academic standard for teaching purposes is a major factor contributing to the slow uptake of ...

  3. Image quality in thoracic 4D cone-beam CT: A sensitivity analysis of respiratory signal, binning method, reconstruction algorithm, and projection angular spacing

    International Nuclear Information System (INIS)

    Shieh, Chun-Chien; Kipritidis, John; O’Brien, Ricky T.; Keall, Paul J.; Kuncic, Zdenka

    2014-01-01

    Purpose: Respiratory signal, binning method, and reconstruction algorithm are three major controllable factors affecting image quality in thoracic 4D cone-beam CT (4D-CBCT), which is widely used in image guided radiotherapy (IGRT). Previous studies have investigated each of these factors individually, but no integrated sensitivity analysis has been performed. In addition, projection angular spacing is also a key factor in reconstruction, but how it affects image quality is not obvious. An investigation of the impacts of these four factors on image quality can help determine the most effective strategy in improving 4D-CBCT for IGRT. Methods: Fourteen 4D-CBCT patient projection datasets with various respiratory motion features were reconstructed with the following controllable factors: (i) respiratory signal (real-time position management, projection image intensity analysis, or fiducial marker tracking), (ii) binning method (phase, displacement, or equal-projection-density displacement binning), and (iii) reconstruction algorithm [Feldkamp–Davis–Kress (FDK), McKinnon–Bates (MKB), or adaptive-steepest-descent projection-onto-convex-sets (ASD-POCS)]. The image quality was quantified using signal-to-noise ratio (SNR), contrast-to-noise ratio, and edge-response width in order to assess noise/streaking and blur. The SNR values were also analyzed with respect to the maximum, mean, and root-mean-squared-error (RMSE) projection angular spacing to investigate how projection angular spacing affects image quality. Results: The choice of respiratory signals was found to have no significant impact on image quality. Displacement-based binning was found to be less prone to motion artifacts compared to phase binning in more than half of the cases, but was shown to suffer from large interbin image quality variation and large projection angular gaps. Both MKB and ASD-POCS resulted in noticeably improved image quality almost 100% of the time relative to FDK. In addition, SNR

  4. Image quality in thoracic 4D cone-beam CT: A sensitivity analysis of respiratory signal, binning method, reconstruction algorithm, and projection angular spacing

    Energy Technology Data Exchange (ETDEWEB)

    Shieh, Chun-Chien [Radiation Physics Laboratory, Sydney Medical School, University of Sydney, NSW 2006, Australia and Institute of Medical Physics, School of Physics, University of Sydney, NSW 2006 (Australia); Kipritidis, John; O’Brien, Ricky T.; Keall, Paul J., E-mail: paul.keall@sydney.edu.au [Radiation Physics Laboratory, Sydney Medical School, University of Sydney, NSW 2006 (Australia); Kuncic, Zdenka [Institute of Medical Physics, School of Physics, University of Sydney, NSW 2006 (Australia)

    2014-04-15

    Purpose: Respiratory signal, binning method, and reconstruction algorithm are three major controllable factors affecting image quality in thoracic 4D cone-beam CT (4D-CBCT), which is widely used in image guided radiotherapy (IGRT). Previous studies have investigated each of these factors individually, but no integrated sensitivity analysis has been performed. In addition, projection angular spacing is also a key factor in reconstruction, but how it affects image quality is not obvious. An investigation of the impacts of these four factors on image quality can help determine the most effective strategy in improving 4D-CBCT for IGRT. Methods: Fourteen 4D-CBCT patient projection datasets with various respiratory motion features were reconstructed with the following controllable factors: (i) respiratory signal (real-time position management, projection image intensity analysis, or fiducial marker tracking), (ii) binning method (phase, displacement, or equal-projection-density displacement binning), and (iii) reconstruction algorithm [Feldkamp–Davis–Kress (FDK), McKinnon–Bates (MKB), or adaptive-steepest-descent projection-onto-convex-sets (ASD-POCS)]. The image quality was quantified using signal-to-noise ratio (SNR), contrast-to-noise ratio, and edge-response width in order to assess noise/streaking and blur. The SNR values were also analyzed with respect to the maximum, mean, and root-mean-squared-error (RMSE) projection angular spacing to investigate how projection angular spacing affects image quality. Results: The choice of respiratory signals was found to have no significant impact on image quality. Displacement-based binning was found to be less prone to motion artifacts compared to phase binning in more than half of the cases, but was shown to suffer from large interbin image quality variation and large projection angular gaps. Both MKB and ASD-POCS resulted in noticeably improved image quality almost 100% of the time relative to FDK. In addition, SNR

  5. Search for CP violation in the decay D{sup +}→π{sup −}π{sup +}π{sup +}

    Energy Technology Data Exchange (ETDEWEB)

    Aaij, R. [Nikhef National Institute for Subatomic Physics, Amsterdam (Netherlands); Adeva, B. [Universidad de Santiago de Compostela, Santiago de Compostela (Spain); Adinolfi, M. [H.H. Wills Physics Laboratory, University of Bristol, Bristol (United Kingdom); Adrover, C. [CPPM, Aix-Marseille Université, CNRS/IN2P3, Marseille (France); Affolder, A. [Oliver Lodge Laboratory, University of Liverpool, Liverpool (United Kingdom); Ajaltouni, Z. [Clermont Université, Université Blaise Pascal, CNRS/IN2P3, LPC, Clermont-Ferrand (France); Albrecht, J. [Fakultät Physik, Technische Universität Dortmund, Dortmund (Germany); Alessio, F. [European Organization for Nuclear Research (CERN), Geneva (Switzerland); Alexander, M. [School of Physics and Astronomy, University of Glasgow, Glasgow (United Kingdom); Ali, S. [Nikhef National Institute for Subatomic Physics, Amsterdam (Netherlands); Alkhazov, G. [Petersburg Nuclear Physics Institute (PNPI), Gatchina (Russian Federation); Alvarez Cartelle, P. [Universidad de Santiago de Compostela, Santiago de Compostela (Spain); Alves, A.A. [Sezione INFN di Roma La Sapienza, Roma (Italy); Amato, S. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro (Brazil); Amerio, S. [Sezione INFN di Padova, Padova (Italy); Amhis, Y. [LAL, Université Paris-Sud, CNRS/IN2P3, Orsay (France); Anderlini, L. [Sezione INFN di Firenze, Firenze (Italy); Anderson, J. [Physik-Institut, Universität Zürich, Zürich (Switzerland); Andreassen, R. [University of Cincinnati, Cincinnati, OH (United States); Andreotti, M. [Sezione INFN di Ferrara, Ferrara (Italy); and others

    2014-01-20

    A search for CP violation in the phase space of the decay D{sup +}→π{sup −}π{sup +}π{sup +} is reported using pp collision data, corresponding to an integrated luminosity of 1.0 fb{sup −1}, collected by the LHCb experiment at a centre-of-mass energy of 7 TeV. The Dalitz plot distributions for 3.1×10{sup 6}D{sup +} and D{sup −} candidates are compared with binned and unbinned model-independent techniques. No evidence for CP violation is found.

  6. Atomic density effects on temperature characteristics and thermal transport at grain boundaries through a proper bin size selection

    Energy Technology Data Exchange (ETDEWEB)

    Vo, Truong Quoc; Kim, BoHung, E-mail: muratbarisik@iyte.edu.tr, E-mail: bohungk@ulsan.ac.kr [School of Mechanical Engineering, University of Ulsan, Daehak-ro 93, Namgu, Ulsan 680-749 (Korea, Republic of); Barisik, Murat, E-mail: muratbarisik@iyte.edu.tr, E-mail: bohungk@ulsan.ac.kr [Department of Mechanical Engineering, Izmir Institute of Technology, Urla, Izmir 35430 (Turkey)

    2016-05-21

    This study focuses on the proper characterization of temperature profiles across grain boundaries (GBs) in order to calculate the correct interfacial thermal resistance (ITR) and reveal the influence of GB geometries onto thermal transport. The solid-solid interfaces resulting from the orientation difference between the (001), (011), and (111) copper surfaces were investigated. Temperature discontinuities were observed at the boundary of grains due to the phonon mismatch, phonon backscattering, and atomic forces between dissimilar structures at the GBs. We observed that the temperature decreases gradually in the GB area rather than a sharp drop at the interface. As a result, three distinct temperature gradients developed at the GB which were different than the one observed in the bulk solid. This behavior extends a couple molecular diameters into both sides of the interface where we defined a thickness at GB based on the measured temperature profiles for characterization. Results showed dependence on the selection of the bin size used to average the temperature data from the molecular dynamics system. The bin size on the order of the crystal layer spacing was found to present an accurate temperature profile through the GB. We further calculated the GB thickness of various cases by using potential energy (PE) distributions which showed agreement with direct measurements from the temperature profile and validated the proper binning. The variation of grain crystal orientation developed different molecular densities which were characterized by the average atomic surface density (ASD) definition. Our results revealed that the ASD is the primary factor affecting the structural disorders and heat transfer at the solid-solid interfaces. Using a system in which the planes are highly close-packed can enhance the probability of interactions and the degree of overlap between vibrational density of states (VDOS) of atoms forming at interfaces, leading to a reduced ITR. Thus, an

  7. Pencarian Produk yang Mirip Melalui Automatic Online Annotation dari Web dan Berbasiskan Konten dengan Color Histogram Bin dan Surf Descriptor

    Directory of Open Access Journals (Sweden)

    Putra Pandu Adikara

    2018-03-01

    Full Text Available Banyaknya situs e-commerce memberikan kemudahan bagi pengguna yang ingin mencari dan membeli suatu produk, misalnya membeli makanan, obat, alat elektronik, kebutuhan sehari-hari, dan lain-lain. Pencarian suatu produk terhadap beberapa situs e-commerce akan menjadi sulit karena banyaknya pilihan situs, banyaknya penjual (merchant/seller yang menjual barang yang sama, dan waktu yang lama karena harus berpindah-pindah situs hingga menemukan produk yang diinginkan. Selain itu dengan adanya teknologi smartphone berkamera, augmented reality, query pencarian bisa jadi hanya berupa citra, namun pencarian produk dengan menggunakan citra pada umumnya tidak diakomodasi di situs e-commerce. Dalam penelitian ini dikembangkan sistem meta search-engine yang menggunakan query berupa citra dan berbasiskan konten untuk menggabungkan hasil pencarian dari beberapa situs e-commerce. Citra query yang tidak diketahui namanya dibangkitkan tag atau kata kuncinya melalui Google reverse image search engine. Kata kunci ini kemudian diberikan ke masing-masing situs e-commerce untuk dilakukan pencarian. Fitur yang digunakan dalam pencocokan query dengan produk adalah fitur tekstual, color histogram bin, dan keberadaan citra objek yang dicari menggunakan SURF descriptor. Fitur-fitur ini digunakan untuk menentukan relevansi terhadap hasil penelusuran. Sistem ini dapat memberikan hasil yang baik dengan precision@20 dan recall hingga 1 dengan rata-rata precision@20 dan recall masing-masing sebesar 0,564 dan 0,608, namun juga bisa gagal dengan precision@20 dan recall sebesar 0. Hasil yang kurang baik ini dikarenakan tag yang dibangkitkan terlalu umum dan situs e-commerce-pun memberikan hasil yang umum juga

  8. An application of the ESD framework to the probabilistic risk assessment of dynamic systems

    International Nuclear Information System (INIS)

    Swaminathan, S.; Smidts, Carol

    2000-01-01

    Dynamic reliability is the probabilistic study of man-machine-software systems affected by an underlying physical process. The theory of probabilistic dynamics established that dynamic reliability methodologies are essentially semi-Markovian frameworks and can be expressed by an extension of the Chapman-Kolmogorov equation. The mathematical complexity associated with the assessment of dynamic systems' behaviour can be rather overwhelming for real life size systems. This is due to the fact that dynamic methodologies emphasize a component based representation rather than the sequence based representation used in the traditional Event Tree/Fault Tree framework or in the original Event Sequence Diagram (ESD) Framework. An extension of the ESD framework was proposed that facilitates capture of dynamic situations. The modeling framework is composed of events, gates, conditions, competitions and constraints which express many of the dynamic situations encountered in the evolution of accidents. The following paper illustrates an application of this extended ESD framework on a complex dynamic application. The problem at hand is an extension of a problem extensively studied in the validation of dynamic reliability algorithms, a simplified model of the fast reactor Europa. A discussion on how ESDs can help in guiding dynamic reliability simulations as well as aggregating and binning the numerous scenarios generated by dynamic reliability algorithms is provided.(author)

  9. The job-search grind: perceived progress, self-reactions, and self-regulation of search effort

    NARCIS (Netherlands)

    Wanberg, C.; Zhu, J.; van Hooft, E.A.J.

    2010-01-01

    Guided by theory and research on self-regulation and goal pursuit, we offer a framework for studying the dynamics of unemployed individuals’ job search. A daily survey over three weeks demonstrated vacillation in job seeker affect and, to a lesser extent, "reemployment efficacy." Daily perceived job

  10. Information retrieval for children based on the aggregated search paradigm

    NARCIS (Netherlands)

    Duarte Torres, Sergio

    This report presents research to develop information services for children by expanding and adapting current Information retrieval technologies according to the search characteristics and needs of children. Concretely, we will employ the aggregated search paradigm as theoretical framework. The

  11. (Re)interpreting LHC New Physics Search Results : Tools and Methods, 3rd Workshop

    CERN Document Server

    The quest for new physics beyond the SM is arguably the driving topic for LHC Run2. LHC collaborations are pursuing searches for new physics in a vast variety of channels. Although collaborations provide various interpretations for their search results, the full understanding of these results requires a much wider interpretation scope involving all kinds of theoretical models. This is a very active field, with close theory-experiment interaction. In particular, development of dedicated methodologies and tools is crucial for such scale of interpretation. Recently, a Forum was initiated to host discussions among LHC experimentalists and theorists on topics related to the BSM (re)interpretation of LHC data, and especially on the development of relevant interpretation tools and infrastructure: https://twiki.cern.ch/twiki/bin/view/LHCPhysics/InterpretingLHCresults Two meetings were held at CERN, where active discussions and concrete work on (re)interpretation methods and tools took place, with valuable cont...

  12. Test Anxiety & Its Relation to Perceived Academic Self-Efficacy among Al Hussein Bin Talal University Students

    Science.gov (United States)

    sa'ad alzboon, Habis

    2016-01-01

    This study aimed to identify the degree of perceived academic self-efficacy and the relationship nature between test anxiety and perceived academic self-efficacy among students of Al Hussein Bin Talal University (AHU). Moreover, to identify the degree of available statistical significance differences that are attributed to gender, college and…

  13. BEACON : A Summary Framework to Overcome Potential Reimbursement Hurdles

    NARCIS (Netherlands)

    Dunlop, William C. N.; Mullins, C. Daniel; Pirk, Olaf; Goeree, Ron; Postma, Maarten J.; Enstone, Ashley; Heron, Louise

    2016-01-01

    Objective To provide a framework for addressing payers' criteria during the development of pharmaceuticals. Methods A conceptual framework was presented to an international health economic expert panel for discussion. A structured literature search (from 2010 to May 2015), using the following

  14. Adaptive Lévy processes and area-restricted search in human foraging.

    Directory of Open Access Journals (Sweden)

    Thomas T Hills

    Full Text Available A considerable amount of research has claimed that animals' foraging behaviors display movement lengths with power-law distributed tails, characteristic of Lévy flights and Lévy walks. Though these claims have recently come into question, the proposal that many animals forage using Lévy processes nonetheless remains. A Lévy process does not consider when or where resources are encountered, and samples movement lengths independently of past experience. However, Lévy processes too have come into question based on the observation that in patchy resource environments resource-sensitive foraging strategies, like area-restricted search, perform better than Lévy flights yet can still generate heavy-tailed distributions of movement lengths. To investigate these questions further, we tracked humans as they searched for hidden resources in an open-field virtual environment, with either patchy or dispersed resource distributions. Supporting previous research, for both conditions logarithmic binning methods were consistent with Lévy flights and rank-frequency methods-comparing alternative distributions using maximum likelihood methods-showed the strongest support for bounded power-law distributions (truncated Lévy flights. However, goodness-of-fit tests found that even bounded power-law distributions only accurately characterized movement behavior for 4 (out of 32 participants. Moreover, paths in the patchy environment (but not the dispersed environment showed a transition to intensive search following resource encounters, characteristic of area-restricted search. Transferring paths between environments revealed that paths generated in the patchy environment were adapted to that environment. Our results suggest that though power-law distributions do not accurately reflect human search, Lévy processes may still describe movement in dispersed environments, but not in patchy environments-where search was area-restricted. Furthermore, our results

  15. Phased searching with NEAT in a time-scaled framework: experiments on a computer-aided detection system for lung nodules.

    Science.gov (United States)

    Tan, Maxine; Deklerck, Rudi; Cornelis, Jan; Jansen, Bart

    2013-11-01

    In the field of computer-aided detection (CAD) systems for lung nodules in computed tomography (CT) scans, many image features are presented and many artificial neural network (ANN) classifiers with various structural topologies are analyzed; frequently, the classifier topologies are selected by trial-and-error experiments. To avoid these trial and error approaches, we present a novel classifier that evolves ANNs using genetic algorithms, called "Phased Searching with NEAT in a Time or Generation-Scaled Framework", integrating feature selection with the classification task. We analyzed our method's performance on 360 CT scans from the public Lung Image Database Consortium database. We compare our method's performance with other more-established classifiers, namely regular NEAT, Feature-Deselective NEAT (FD-NEAT), fixed-topology ANNs, and support vector machines (SVMs) using ten-fold cross-validation experiments of all 360 scans. The results show that the proposed "Phased Searching" method performs better and faster than regular NEAT, better than FD-NEAT, and achieves sensitivities at 3 and 4 false positives (FP) per scan that are comparable with the fixed-topology ANN and SVM classifiers, but with fewer input features. It achieves a detection sensitivity of 83.0±9.7% with an average of 4FP/scan, for nodules with a diameter greater than or equal to 3mm. It also evolves networks with shorter evolution times and with lower complexities than regular NEAT (p=0.026 and pNEAT and by our approach shows that our approach searches for good solutions in lower dimensional search spaces, and evolves networks without superfluous structure. We have presented a novel approach that combines feature selection with the evolution of ANN topology and weights. Compared with the original threshold-based Phased Searching method of Green, our method requires fewer parameters and converges to the optimal network complexity required for the classification task at hand. The results of the

  16. Internet Addiction and Its Relationship with Self-Efficacy Level among Al-Hussein Bin Talal University Students

    Science.gov (United States)

    Alrekebat, Amjad Farhan

    2016-01-01

    The aim of this study was to identify the Internet addiction and its relationship to self-efficacy level among Al-Hussein Bin Talal University students. The study sample consisted of 300 female and male students, who were selected randomly. The participants completed a questionnaire that consisted of two scales: Internet addiction which was…

  17. A survey of open source multiphysics frameworks in engineering

    NARCIS (Netherlands)

    Babur, O.; Smilauer, V.; Verhoeff, T.; Brand, van den M.G.J.

    2015-01-01

    This paper presents a systematic survey of open source multiphysics frameworks in the en- gineering domains. These domains share many commonalities despite the diverse application areas. A thorough search for the available frameworks with both academic and industrial ori- gins has revealed numerous

  18. Search for new phenomena in events with a highly energetic jet and missing transverse momentum with the ATLAS detector

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00387867

    This thesis present the search for new phenomena in events with a highly energetic jet and large missing transverse momentum at ATLAS with data collected in Run 2 during 2015 and 2016 corresponding to 36.1 fb-1. This search, also referred to as 'monojet search' exhibits a unique sensitivity to BSM models predicting heavy particles that may escape the detector untraced. If an object, such as a jet, recoils against these particles a monojet signature is produced. The search exploits the discrimination power of the E_{T}^{miss} spectrum between background and BSM signals. The E_{T}^{miss} spectrum is fitted in 10 bins in four orthogonal control regions simultaneously to estimate the background contribution in the signal region and determine the probability of various signal hypothesis from the observed data distribution. The fit model relies on state of the art theory predictions concerning NLO QCD and nNLO EW corrections to the major V+jets backgrounds and uses as well data driven techniques. Therefore, the pr...

  19. Longitudinal Acceleration Test of Overhead Luggage Bins and Auxiliary Fuel Tank in a Transport Airplane Airframe Section, Part 2

    National Research Council Canada - National Science Library

    McGuire, Robert

    2000-01-01

    This report contains the description and test results of overhead stowage bin calibrations and longitudinal impact testing of a 10-foot transport airframe section conducted at the Transportation Research Center Inc. (TRC...

  20. Optimal Search for an Astrophysical Gravitational-Wave Background

    Science.gov (United States)

    Smith, Rory; Thrane, Eric

    2018-04-01

    Roughly every 2-10 min, a pair of stellar-mass black holes merge somewhere in the Universe. A small fraction of these mergers are detected as individually resolvable gravitational-wave events by advanced detectors such as LIGO and Virgo. The rest contribute to a stochastic background. We derive the statistically optimal search strategy (producing minimum credible intervals) for a background of unresolved binaries. Our method applies Bayesian parameter estimation to all available data. Using Monte Carlo simulations, we demonstrate that the search is both "safe" and effective: it is not fooled by instrumental artifacts such as glitches and it recovers simulated stochastic signals without bias. Given realistic assumptions, we estimate that the search can detect the binary black hole background with about 1 day of design sensitivity data versus ≈40 months using the traditional cross-correlation search. This framework independently constrains the merger rate and black hole mass distribution, breaking a degeneracy present in the cross-correlation approach. The search provides a unified framework for population studies of compact binaries, which is cast in terms of hyperparameter estimation. We discuss a number of extensions and generalizations, including application to other sources (such as binary neutron stars and continuous-wave sources), simultaneous estimation of a continuous Gaussian background, and applications to pulsar timing.

  1. Searches for Dark Matter with in Events with Hadronic Activity

    CERN Document Server

    The ATLAS collaboration

    2017-01-01

    The astrophysical evidence of dark matter provides some of the most compelling clues to the nature of physics beyond the Standard Model. From these clues, ATLAS has developed a broad and systematic search program for dark matter production in LHC collisions. In the framework of Simplified models the searches are divided into invisible and visible channels, corresponding to dark matter searches, with a missing energy signature, and dark matter mediator searches, looking for bump in invariant mass distributions.

  2. Methodology, theoretical framework and scholarly significance: An ...

    African Journals Online (AJOL)

    Methodology, theoretical framework and scholarly significance: An overview ... AFRICAN JOURNALS ONLINE (AJOL) · Journals · Advanced Search ... Keywords: Legal Research, Methodology, Theory, Pedagogy, Legal Training, Scholarship ...

  3. Evaluation of methods for selecting the midventilation bin in 4DCT scans of lung cancer patients

    DEFF Research Database (Denmark)

    Nygaard, Ditte Eklund; Persson, Gitte Fredberg; Brink, Carsten

    2013-01-01

    based on: 1) visual evaluation of tumour displacement; 2) rigid registration of tumour position; 3) diaphragm displacement in the CC direction; and 4) carina displacement in the CC direction. Determination of the MidV bin based on the displacement of the manually delineated gross tumour volume (GTV.......4-5.4) mm, 1.9 (0.5-6.9) mm, 2.0 (0.5-12.3) mm and 1.1 (0.4-5.4) mm for the visual, rigid registration, diaphragm, carina, and reference method. Median (range) absolute difference between geometric MidV error for the evaluated methods and the reference method was 0.0 (0.0-1.2) mm, 0.0 (0.0-1.7) mm, 0.7 (0.......0-3.9) mm and 1.0 (0.0-6.9) mm for the visual, rigid registration, diaphragm and carina method. Conclusion. The visual and semi-automatic rigid registration methods were equivalent in accuracy for selecting the MidV bin of a 4DCT scan. The methods based on diaphragm and carina displacement cannot...

  4. Collaborative Search Strategies for Green Innovation

    DEFF Research Database (Denmark)

    Ørding Olsen, Anders; Sofka, Wolfgang; Grimpe, Christoph

    Recent innovation and strategy research emphasizes the importance of firm’s search for external knowledge to improve innovation performance. We focus on such search strategies within the domain of sustainable innovation in which problems are inherently complex and the relevant knowledge is widely...... dispersed. Hence, firms need to collaborate. We shed new light on collaborative search strategies led by firms in general and for solving environmental problems in particular. Both topics are largely absent in the extant open innovation literature. Using data from the European Seventh Framework Program...... for Research and Technological Development (FP7), our results indicate that the problem-solving potential of a search strategy increases with the diversity of existing knowledge of the partners in a consortium and with the experience of the partners involved. Moreover, we identify a substantial negative effect...

  5. MetaABC--an integrated metagenomics platform for data adjustment, binning and clustering.

    Science.gov (United States)

    Su, Chien-Hao; Hsu, Ming-Tsung; Wang, Tse-Yi; Chiang, Sufeng; Cheng, Jen-Hao; Weng, Francis C; Kao, Cheng-Yan; Wang, Daryi; Tsai, Huai-Kuang

    2011-08-15

    MetaABC is a metagenomic platform that integrates several binning tools coupled with methods for removing artifacts, analyzing unassigned reads and controlling sampling biases. It allows users to arrive at a better interpretation via series of distinct combinations of analysis tools. After execution, MetaABC provides outputs in various visual formats such as tables, pie and bar charts as well as clustering result diagrams. MetaABC source code and documentation are available at http://bits2.iis.sinica.edu.tw/MetaABC/ CONTACT: dywang@gate.sinica.edu.tw; hktsai@iis.sinica.edu.tw Supplementary data are available at Bioinformatics online.

  6. APT Blanket Detailed Bin Model Based on Initial Plate-Type Design -3D FLOWTRAN-TF Model

    International Nuclear Information System (INIS)

    Hamm, L.L.

    1998-01-01

    This report provides background information for a series of reports documenting accident scenario simulations for the Accelerator Production of Tritium (APT) blanket heat removal systems. The simulations were performed in support of the Preliminary Safety Analysis Report for the APT. This report gives a brief description of the FLOWTRAN-TF code which was used for detailed blanket bin modeling

  7. Scoping review identifies significant number of knowledge translation theories, models and frameworks with limited use.

    Science.gov (United States)

    Strifler, Lisa; Cardoso, Roberta; McGowan, Jessie; Cogo, Elise; Nincic, Vera; Khan, Paul A; Scott, Alistair; Ghassemi, Marco; MacDonald, Heather; Lai, Yonda; Treister, Victoria; Tricco, Andrea C; Straus, Sharon E

    2018-04-13

    To conduct a scoping review of knowledge translation (KT) theories, models and frameworks that have been used to guide dissemination or implementation of evidence-based interventions targeted to prevention and/or management of cancer or other chronic diseases. We used a comprehensive multistage search process from 2000-2016, which included traditional bibliographic database searching, searching using names of theories, models and frameworks, and cited reference searching. Two reviewers independently screened the literature and abstracted data. We found 596 studies reporting on the use of 159 KT theories, models or frameworks. A majority (87%) of the identified theories, models or frameworks were used in five or fewer studies, with 60% used once. The theories, models and frameworks were most commonly used to inform planning/design, implementation and evaluation activities, and least commonly used to inform dissemination and sustainability/scalability activities. Twenty-six were used across the full implementation spectrum (from planning/design to sustainability/scalability) either within or across studies. All were used for at least individual-level behavior change, while 48% were used for organization-level, 33% for community-level and 17% for system-level change. We found a significant number of KT theories, models and frameworks with a limited evidence base describing their use. Copyright © 2018. Published by Elsevier Inc.

  8. Fit of screw-retained fixed implant frameworks fabricated by different methods: a systematic review.

    Science.gov (United States)

    Abduo, Jaafar; Lyons, Karl; Bennani, Vincent; Waddell, Neil; Swain, Michael

    2011-01-01

    The aim of this study was to review the published literature investigating the accuracy of fit of fixed implant frameworks fabricated using different materials and methods. A comprehensive electronic search was performed through PubMed (MEDLINE) using Boolean operators to combine key words. The search was limited to articles written in English and published through May 2010. In addition, a manual search through articles and reference lists retrieved from the electronic search and peer-reviewed journals was also conducted. A total of 248 articles were retrieved, and 26 met the specified inclusion criteria for the review. The selected articles assessed the fit of fixed implant frameworks fabricated by different techniques. The investigated fabrication approaches were one-piece casting, sectioning and reconnection, spark erosion with an electric discharge machine, computer-aided design/computer-assisted manufacturing (CAD/CAM), and framework bonding to prefabricated abutment cylinders. Cast noble metal frameworks have a predictable fit, and additional fit refinement treatment is not indicated in well-controlled conditions. Base metal castings do not provide a satisfactory level of fit unless additional refinement treatment is performed, such as sectioning and laser welding or spark erosion. Spark erosion, framework bonding to prefabricated abutment cylinders, and CAD/CAM have the potential to provide implant frameworks with an excellent fit; CAD/CAM is the most consistent and least technique-sensitive of these methods.

  9. Designing a power supply for Nim-bin formatted equipment; Diseno de una fuente de alimentacion para equipos con formato Nim-bin

    Energy Technology Data Exchange (ETDEWEB)

    Banuelos G, L. E.; Hernandez D, V. M.; Vega C, H. R., E-mail: lebluis2012@hotmail.com [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98060 Zacatecas, Zac. (Mexico)

    2016-09-15

    From an old Nuclear Chicago power supply that was practically in the trash, was able to recover the 19 inches casing, rear connectors and the housing where the circuits were. From here all mechanical parts were cleaned and the electronic design was started to replace the original voltage and current functions of this equipment. The cards for the ±6, ±12 and ±24 voltages were designed, simulated and tested with circuitry that does not rely on specialized components or that is sold only by the equipment manufacturer. In the handling of the current by each voltage to operate, was possible to tie with the specifications of the manufacturers like Ortec or Canberra where a model of power supply gives a power of 160 Watts. Basic tests were performed to show that the behavior is very similar to commercial equipment; such as the full load regulation index and the noise level in the supply voltages. So our Nim-bin voltage source is viable for use in our institution laboratories. (Author)

  10. A hybrid adaptive large neighborhood search algorithm applied to a lot-sizing problem

    DEFF Research Database (Denmark)

    Muller, Laurent Flindt; Spoorendonk, Simon

    This paper presents a hybrid of a general heuristic framework that has been successfully applied to vehicle routing problems and a general purpose MIP solver. The framework uses local search and an adaptive procedure which choses between a set of large neighborhoods to be searched. A mixed integer...... of a solution and to investigate the feasibility of elements in such a neighborhood. The hybrid heuristic framework is applied to the multi-item capacitated lot sizing problem with dynamic lot sizes, where experiments have been conducted on a series of instances from the literature. On average the heuristic...

  11. Mida teie oma tervise heaks teete? / Ly Jagor, Ülle Mihhailova, Ene Pill, Katrin Käbin...[jt.

    Index Scriptorium Estoniae

    2008-01-01

    Küsimusele vastavad Pärnu Õppenõustamiskeskuse psühholoog Ly Jagor, Maasika lasteaia juhataja asetäitja Ülle Mihhailova, Tallinna Perekeskuse ja Tähetorni lastekeskuse psühholoog Ene Pill, Tallinna Nõmme Noortemaja väikelaste ringijuht Katrin Käbin, Tääksi Põhikooli õpetaja Silva Kolk

  12. Optimal Search for an Astrophysical Gravitational-Wave Background

    Directory of Open Access Journals (Sweden)

    Rory Smith

    2018-04-01

    Full Text Available Roughly every 2–10 min, a pair of stellar-mass black holes merge somewhere in the Universe. A small fraction of these mergers are detected as individually resolvable gravitational-wave events by advanced detectors such as LIGO and Virgo. The rest contribute to a stochastic background. We derive the statistically optimal search strategy (producing minimum credible intervals for a background of unresolved binaries. Our method applies Bayesian parameter estimation to all available data. Using Monte Carlo simulations, we demonstrate that the search is both “safe” and effective: it is not fooled by instrumental artifacts such as glitches and it recovers simulated stochastic signals without bias. Given realistic assumptions, we estimate that the search can detect the binary black hole background with about 1 day of design sensitivity data versus ≈40 months using the traditional cross-correlation search. This framework independently constrains the merger rate and black hole mass distribution, breaking a degeneracy present in the cross-correlation approach. The search provides a unified framework for population studies of compact binaries, which is cast in terms of hyperparameter estimation. We discuss a number of extensions and generalizations, including application to other sources (such as binary neutron stars and continuous-wave sources, simultaneous estimation of a continuous Gaussian background, and applications to pulsar timing.

  13. The EMBL-EBI bioinformatics web and programmatic tools framework.

    Science.gov (United States)

    Li, Weizhong; Cowley, Andrew; Uludag, Mahmut; Gur, Tamer; McWilliam, Hamish; Squizzato, Silvano; Park, Young Mi; Buso, Nicola; Lopez, Rodrigo

    2015-07-01

    Since 2009 the EMBL-EBI Job Dispatcher framework has provided free access to a range of mainstream sequence analysis applications. These include sequence similarity search services (https://www.ebi.ac.uk/Tools/sss/) such as BLAST, FASTA and PSI-Search, multiple sequence alignment tools (https://www.ebi.ac.uk/Tools/msa/) such as Clustal Omega, MAFFT and T-Coffee, and other sequence analysis tools (https://www.ebi.ac.uk/Tools/pfa/) such as InterProScan. Through these services users can search mainstream sequence databases such as ENA, UniProt and Ensembl Genomes, utilising a uniform web interface or systematically through Web Services interfaces (https://www.ebi.ac.uk/Tools/webservices/) using common programming languages, and obtain enriched results with novel visualisations. Integration with EBI Search (https://www.ebi.ac.uk/ebisearch/) and the dbfetch retrieval service (https://www.ebi.ac.uk/Tools/dbfetch/) further expands the usefulness of the framework. New tools and updates such as NCBI BLAST+, InterProScan 5 and PfamScan, new categories such as RNA analysis tools (https://www.ebi.ac.uk/Tools/rna/), new databases such as ENA non-coding, WormBase ParaSite, Pfam and Rfam, and new workflow methods, together with the retirement of depreciated services, ensure that the framework remains relevant to today's biological community. © The Author(s) 2015. Published by Oxford University Press on behalf of Nucleic Acids Research.

  14. Considerations for the development of task-based search engines

    DEFF Research Database (Denmark)

    Petcu, Paula; Dragusin, Radu

    2013-01-01

    Based on previous experience from working on a task-based search engine, we present a list of suggestions and ideas for an Information Retrieval (IR) framework that could inform the development of next generation professional search systems. The specific task that we start from is the clinicians......' information need in finding rare disease diagnostic hypotheses at the time and place where medical decisions are made. Our experience from the development of a search engine focused on supporting clinicians in completing this task has provided us valuable insights in what aspects should be considered...... by the developers of vertical search engines....

  15. Quality Dimensions of Internet Search Engines.

    Science.gov (United States)

    Xie, M.; Wang, H.; Goh, T. N.

    1998-01-01

    Reviews commonly used search engines (AltaVista, Excite, infoseek, Lycos, HotBot, WebCrawler), focusing on existing comparative studies; considers quality dimensions from the customer's point of view based on a SERVQUAL framework; and groups these quality expectations in five dimensions: tangibles, reliability, responsiveness, assurance, and…

  16. Measuring Device for Air Speed in Macroporous Media and Its Application Inside Apple Storage Bins

    Directory of Open Access Journals (Sweden)

    Martin Geyer

    2018-02-01

    Full Text Available In cold storage facilities of fruit and vegetables, airflow is necessary for heat removal. The design of storage facilities influences the air speed in the surrounding of the product. Therefore, knowledge about airflow next to the product is important to plan the layout of cold stores adapted to the requirements of the products. A new sensing device (ASL, Air speed logger is developed for omnidirectional measurement of air speed between fruit or vegetables inside storage bins or in bulk. It consists of four interconnected plastic spheres with 80 mm diameter each, adapted to the size of apple fruit. In the free space between the spheres, silicon diodes are fixed for the airflow measurement based on a calorimetric principle. Battery and data logger are mounted inside the spheres. The device is calibrated in a wind tunnel in a measuring range of 0–1.3 m/s. Air speed measurements in fruit bulks on laboratory scale and in an industrial fruit store show air speeds in gaps between fruit with high stability at different airflow levels. Several devices can be placed between stored products for determination of the air speed distribution inside bulks or bin stacks in a storage room.

  17. BAC-end sequence-based SNPs and Bin mapping for rapid integration of physical and genetic maps in apple.

    Science.gov (United States)

    Han, Yuepeng; Chagné, David; Gasic, Ksenija; Rikkerink, Erik H A; Beever, Jonathan E; Gardiner, Susan E; Korban, Schuyler S

    2009-03-01

    A genome-wide BAC physical map of the apple, Malus x domestica Borkh., has been recently developed. Here, we report on integrating the physical and genetic maps of the apple using a SNP-based approach in conjunction with bin mapping. Briefly, BAC clones located at ends of BAC contigs were selected, and sequenced at both ends. The BAC end sequences (BESs) were used to identify candidate SNPs. Subsequently, these candidate SNPs were genetically mapped using a bin mapping strategy for the purpose of mapping the physical onto the genetic map. Using this approach, 52 (23%) out of 228 BESs tested were successfully exploited to develop SNPs. These SNPs anchored 51 contigs, spanning approximately 37 Mb in cumulative physical length, onto 14 linkage groups. The reliability of the integration of the physical and genetic maps using this SNP-based strategy is described, and the results confirm the feasibility of this approach to construct an integrated physical and genetic maps for apple.

  18. Higgs particle searches at LEP

    International Nuclear Information System (INIS)

    Martin, J.P.

    1996-01-01

    Results on searches for the Higgs particle performed by the four LEP experiments are received in the framework of the Standard Model, Two Doublet Model, and Minimal Supersymmetric Model. The combined mass lower limit for the standard Higgs boson is 66 GeV/c 2 at 95 % CL for a statistics of 14.6 Million hadronic Z decays. (authors)

  19. Computer Aided Solvent Selection and Design Framework

    DEFF Research Database (Denmark)

    Mitrofanov, Igor; Conte, Elisa; Abildskov, Jens

    and computer-aided tools and methods for property prediction and computer-aided molecular design (CAMD) principles. This framework is applicable for solvent selection and design in product design as well as process design. The first module of the framework is dedicated to the solvent selection and design...... in terms of: physical and chemical properties (solvent-pure properties); Environment, Health and Safety (EHS) characteristic (solvent-EHS properties); operational properties (solvent–solute properties). 3. Performing the search. The search step consists of two stages. The first is a generation and property...... identification of solvent candidates using special software ProCAMD and ProPred, which are the implementations of computer-aided molecular techniques. The second consists of assigning the RS-indices following the reaction–solvent and then consulting the known solvent database and identifying the set of solvents...

  20. Explicit Cloud Nucleation from Arbitrary Mixtures of Aerosol Types and Sizes Using an Ultra-Efficient In-Line Aerosol Bin Model in High-Resolution Simulations of Hurricanes

    Science.gov (United States)

    Walko, R. L.; Ashby, T.; Cotton, W. R.

    2017-12-01

    The fundamental role of atmospheric aerosols in the process of cloud droplet nucleation is well known, and there is ample evidence that the concentration, size, and chemistry of aerosols can strongly influence microphysical, thermodynamic, and ultimately dynamic properties and evolution of clouds and convective systems. With the increasing availability of observation- and model-based environmental representations of different types of anthropogenic and natural aerosols, there is increasing need for models to be able to represent which aerosols nucleate and which do not in supersaturated conditions. However, this is a very complex process that involves competition for water vapor between multiple aerosol species (chemistries) and different aerosol sizes within each species. Attempts have been made to parameterize the nucleation properties of mixtures of different aerosol species, but it is very difficult or impossible to represent all possible mixtures that may occur in practice. As part of a modeling study of the impact of anthropogenic and natural aerosols on hurricanes, we developed an ultra-efficient aerosol bin model to represent nucleation in a high-resolution atmospheric model that explicitly represents cloud- and subcloud-scale vertical motion. The bin model is activated at any time and location in a simulation where supersaturation occurs and is potentially capable of activating new cloud droplets. The bins are populated from the aerosol species that are present at the given time and location and by multiple sizes from each aerosol species according to a characteristic size distribution, and the chemistry of each species is represented by its absorption or adsorption characteristics. The bin model is integrated in time increments that are smaller than that of the atmospheric model in order to temporally resolve the peak supersaturation, which determines the total nucleated number. Even though on the order of 100 bins are typically utilized, this leads only

  1. Frameworks for understanding and describing business models

    DEFF Research Database (Denmark)

    Nielsen, Christian; Roslender, Robin

    2014-01-01

    This chapter provides in a chronological fashion an introduction to six frameworks that one can apply to describing, understanding and also potentially innovating business models. These six frameworks have been chosen carefully as they represent six very different perspectives on business models...... and in this manner “complement” each other. There are a multitude of varying frameworks that could be chosen from and we urge the reader to search and trial these for themselves. The six chosen models (year of release in parenthesis) are: • Service-Profit Chain (1994) • Strategic Systems Auditing (1997) • Strategy...... Maps (2001) • Intellectual Capital Statements (2003) • Chesbrough’s framework for Open Business Models (2006) • Business Model Canvas (2008)...

  2. Auditing Search Engines for Differential Satisfaction Across Demographics

    OpenAIRE

    Mehrotra, R.; Anderson, A.; Diaz, F.; Sharma, A.; Wallach, H. M.; Yilmaz, E.

    2017-01-01

    Many online services, such as search engines, social media platforms, and digital marketplaces, are advertised as being available to any user, regardless of their age, gender, or other demographic factors. However, there are growing concerns that these services may systematically underserve some groups of users. In this paper, we present a framework for internally auditing such services for differences in user satisfaction across demographic groups, using search engines as a case study. We fi...

  3. Search for atmospheric muon-neutrinos and extraterrestric neutrino point sources in the 1997 AMANDA-B10 data

    International Nuclear Information System (INIS)

    Biron von Curland, A.

    2002-07-01

    The young field of high energy neutrino astronomy can be motivated by the search for the origin of the charged cosmic rays. Large astrophysical objects like AGNs or supernova remnants are candidates to accelerate hadrons which then can interact to eventually produce high energy neutrinos. Neutrino-induced muons can be detected via their emission of Cherenkov light in large neutrino telescopes like AMANDA. More than 10 9 atmospheric muon events and approximately 5000 atmospheric neutrino events were registered by AMANDA-B10 in 1997. Out of these, 223 atmospheric neutrino candidate events have been extracted. This data set contains approximately 15 background events. It allows to confirm the expected sensitivity of the detector towards neutrino events. A second set containing 369 (approximately 270 atmospheric neutrino events and 100 atmospheric muon events) was used to search for extraterrestrial neutrino point sources. Neither a binned search, nor a cluster search, nor a search for preselected sources gave indications for the existence of a strong neutrino point source. Based on this result, flux limits were derived. Assuming E ν -2 spectra, typical flux limits for selected sources of the order of Φ μ limit ∝ 10 -14 cm -2 s -1 for muons and Φ ν limit ∝ 10 -7 cm -2 s -1 for neutrinos have been obtained. (orig.)

  4. Comparison of compostable bags and aerated bins with conventional storage systems to collect the organic fraction of municipal solid waste from homes. a Catalonia case study.

    Science.gov (United States)

    Puyuelo, Belén; Colón, Joan; Martín, Patrícia; Sánchez, Antoni

    2013-06-01

    The separation of biowaste at home is key to improving, facilitating and reducing the operational costs of the treatment of organic municipal waste. The conventional method of collecting such waste and separating it at home is usually done by using a sealed bin with a plastic bag. The use of modern compostable bags is starting to be implemented in some European countries. These compostable bags are made of biodegradable polymers, often from renewable sources. In addition to compostable bags, a new model of bin is also promoted that has a perforated surface that, together with the compostable bag, makes the so-called "aerated system". In this study, different combinations of home collection systems have been systematically studied in the laboratory and at home. The results obtained quantitatively demonstrate that the aerated bin and compostable bag system combination is effective at improving the collection of biowaste without significant gaseous emissions and preparing the organic waste for further composting as concluded from the respiration indices. In terms of weight loss, temperature, gas emissions, respiration index and organic matter reduction, the best results were achieved with the aerated system. At the same time, a qualitative study of bin and bag combinations was carried in 100 homes in which more than 80% of the families participating preferred the aerated system. Copyright © 2013 Elsevier Ltd. All rights reserved.

  5. Modeling visual search using three-parameter probability functions in a hierarchical Bayesian framework.

    Science.gov (United States)

    Lin, Yi-Shin; Heinke, Dietmar; Humphreys, Glyn W

    2015-04-01

    In this study, we applied Bayesian-based distributional analyses to examine the shapes of response time (RT) distributions in three visual search paradigms, which varied in task difficulty. In further analyses we investigated two common observations in visual search-the effects of display size and of variations in search efficiency across different task conditions-following a design that had been used in previous studies (Palmer, Horowitz, Torralba, & Wolfe, Journal of Experimental Psychology: Human Perception and Performance, 37, 58-71, 2011; Wolfe, Palmer, & Horowitz, Vision Research, 50, 1304-1311, 2010) in which parameters of the response distributions were measured. Our study showed that the distributional parameters in an experimental condition can be reliably estimated by moderate sample sizes when Monte Carlo simulation techniques are applied. More importantly, by analyzing trial RTs, we were able to extract paradigm-dependent shape changes in the RT distributions that could be accounted for by using the EZ2 diffusion model. The study showed that Bayesian-based RT distribution analyses can provide an important means to investigate the underlying cognitive processes in search, including stimulus grouping and the bottom-up guidance of attention.

  6. Beam angle optimization for intensity-modulated radiation therapy using a guided pattern search method

    International Nuclear Information System (INIS)

    Rocha, Humberto; Dias, Joana M; Ferreira, Brígida C; Lopes, Maria C

    2013-01-01

    Generally, the inverse planning of radiation therapy consists mainly of the fluence optimization. The beam angle optimization (BAO) in intensity-modulated radiation therapy (IMRT) consists of selecting appropriate radiation incidence directions and may influence the quality of the IMRT plans, both to enhance better organ sparing and to improve tumor coverage. However, in clinical practice, most of the time, beam directions continue to be manually selected by the treatment planner without objective and rigorous criteria. The goal of this paper is to introduce a novel approach that uses beam’s-eye-view dose ray tracing metrics within a pattern search method framework in the optimization of the highly non-convex BAO problem. Pattern search methods are derivative-free optimization methods that require a few function evaluations to progress and converge and have the ability to better avoid local entrapment. The pattern search method framework is composed of a search step and a poll step at each iteration. The poll step performs a local search in a mesh neighborhood and ensures the convergence to a local minimizer or stationary point. The search step provides the flexibility for a global search since it allows searches away from the neighborhood of the current iterate. Beam’s-eye-view dose metrics assign a score to each radiation beam direction and can be used within the pattern search framework furnishing a priori knowledge of the problem so that directions with larger dosimetric scores are tested first. A set of clinical cases of head-and-neck tumors treated at the Portuguese Institute of Oncology of Coimbra is used to discuss the potential of this approach in the optimization of the BAO problem. (paper)

  7. Self-Referent Constructs and Medical Sociology: In Search of an Integrative Framework*

    Science.gov (United States)

    Kaplan, Howard B.

    2010-01-01

    A theoretical framework centering on four classes of self-referent constructs is offered as a device for integrating the diverse areas constituting medical sociology. Guidance by this framework sensitizes the researcher to the occurrence of parallel processes in adjacent disciplines, facilitates recognition of the etiological significance of findings from other disciplines for explaining medical sociological phenomena, and encourages transactions between sociology and medical sociology whereby each informs and is informed by the other. PMID:17583268

  8. Conformational Smear Characterization and Binning of Single-Molecule Conductance Measurements for Enhanced Molecular Recognition.

    Science.gov (United States)

    Korshoj, Lee E; Afsari, Sepideh; Chatterjee, Anushree; Nagpal, Prashant

    2017-11-01

    Electronic conduction or charge transport through single molecules depends primarily on molecular structure and anchoring groups and forms the basis for a wide range of studies from molecular electronics to DNA sequencing. Several high-throughput nanoelectronic methods such as mechanical break junctions, nanopores, conductive atomic force microscopy, scanning tunneling break junctions, and static nanoscale electrodes are often used for measuring single-molecule conductance. In these measurements, "smearing" due to conformational changes and other entropic factors leads to large variances in the observed molecular conductance, especially in individual measurements. Here, we show a method for characterizing smear in single-molecule conductance measurements and demonstrate how binning measurements according to smear can significantly enhance the use of individual conductance measurements for molecular recognition. Using quantum point contact measurements on single nucleotides within DNA macromolecules, we demonstrate that the distance over which molecular junctions are maintained is a measure of smear, and the resulting variance in unbiased single measurements depends on this smear parameter. Our ability to identify individual DNA nucleotides at 20× coverage increases from 81.3% accuracy without smear analysis to 93.9% with smear characterization and binning (SCRIB). Furthermore, merely 7 conductance measurements (7× coverage) are needed to achieve 97.8% accuracy for DNA nucleotide recognition when only low molecular smear measurements are used, which represents a significant improvement over contemporary sequencing methods. These results have important implications in a broad range of molecular electronics applications from designing robust molecular switches to nanoelectronic DNA sequencing.

  9. Narrative review of frameworks for translating research evidence into policy and practice.

    Science.gov (United States)

    Milat, Andrew J; Li, Ben

    2017-02-15

    A significant challenge in research translation is that interested parties interpret and apply the associated terms and conceptual frameworks in different ways. The purpose of this review was to: a) examine different research translation frameworks; b) examine the similarities and differences between the frameworks; and c) identify key strengths and weaknesses of the models when they are applied in practice. The review involved a keyword search of PubMed. The search string was (translational research OR knowledge translation OR evidence to practice) AND (framework OR model OR theory) AND (public health OR health promotion OR medicine). Included studies were published in English between January 1990 and December 2014, and described frameworks, models or theories associated with research translation. The final review included 98 papers, and 41 different frameworks and models were identified. The most frequently applied knowledge translation framework in the literature was RE-AIM, followed by the knowledge translation continuum or 'T' models, the Knowledge to Action framework, the PARiHS framework, evidence based public health models, and the stages of research and evaluation model. The models identified in this review stem from different fields, including implementation science, basic and medical sciences, health services research and public health, and propose different but related pathways to closing the research-practice gap.

  10. Designing a power supply for Nim-bin formatted equipment

    International Nuclear Information System (INIS)

    Banuelos G, L. E.; Hernandez D, V. M.; Vega C, H. R.

    2016-09-01

    From an old Nuclear Chicago power supply that was practically in the trash, was able to recover the 19 inches casing, rear connectors and the housing where the circuits were. From here all mechanical parts were cleaned and the electronic design was started to replace the original voltage and current functions of this equipment. The cards for the ±6, ±12 and ±24 voltages were designed, simulated and tested with circuitry that does not rely on specialized components or that is sold only by the equipment manufacturer. In the handling of the current by each voltage to operate, was possible to tie with the specifications of the manufacturers like Ortec or Canberra where a model of power supply gives a power of 160 Watts. Basic tests were performed to show that the behavior is very similar to commercial equipment; such as the full load regulation index and the noise level in the supply voltages. So our Nim-bin voltage source is viable for use in our institution laboratories. (Author)

  11. Supersymmetry searches at the LHC and their interpretations

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00389502

    One of the primary goals of the CERN Large Hadron Collider is to search for new physics. Many such searches have been carried out, in particular searches for supersymmetry, yet no new physics beyond the Standard Model has been found. With a large number of free parameters introduced by frameworks such as supersymmetry, it can be difficult to interpret the null results of searches. The first analysis presented in this thesis attempts to tackle this difficulty head-on, and gives a summary of the constraints from the Run-1 ATLAS searches. A combination of 22 searches were used, with integrated luminosities of up to 20.3 inverse femtobarns of 7 and 8 TeV data. The results are interpreted in the context of the 19-dimensional phenomenological MSSM, and are presented in terms of the masses of supersymmetric particles. Constraints from dark matter, heavy flavour and precision electroweak measurements were incorporated, and results are also interpreted in terms of these observables. Properties of models missed by the ...

  12. A frequency bin-wise nonlinear masking algorithm in convolutive mixtures for speech segregation.

    Science.gov (United States)

    Chi, Tai-Shih; Huang, Ching-Wen; Chou, Wen-Sheng

    2012-05-01

    A frequency bin-wise nonlinear masking algorithm is proposed in the spectrogram domain for speech segregation in convolutive mixtures. The contributive weight from each speech source to a time-frequency unit of the mixture spectrogram is estimated by a nonlinear function based on location cues. For each sound source, a non-binary mask is formed from the estimated weights and is multiplied to the mixture spectrogram to extract the sound. Head-related transfer functions (HRTFs) are used to simulate convolutive sound mixtures perceived by listeners. Simulation results show our proposed method outperforms convolutive independent component analysis and degenerate unmixing and estimation technique methods in almost all test conditions.

  13. Fontes binárias supermoles de raios X

    Science.gov (United States)

    Pires, A. M.; Janot Pacheco, E.

    2003-08-01

    Estuda-se as características físicas das fontes supermoles (de raios X (SSS), utilizando dados ópticos e em altas energias, no âmbito de um trabalho de IC. Trata-se de binárias que apresentam espectro X muito mole, baixas temperaturas e altas luminosidades bolométricas. Esse sistemas são compostos por uma anã branca realizando fusão em sua superfície, a partir de matéria perdida pela estrela companheira. Os resíduos de fusão se acumulam na superfície da anã branca, e essa pode ultrapassar o limite de Chadrasekhar, produzir um colapso gravitacional, sendo esse um dos cenários propostos para as explosões de SN Ia. Apresentamos nesta comunicação o estado da arte das características físicas das fontes SSS, situando-as no âmbito das VCs. Procuramos também situar esses objetos em relação às variáveis galácticas V Sge, na medida em que os dois grupos apresentam certas caracerísticas bastante semelhantes.A metodologia adotada é aquela pedagógico-cognitiva clássica de um trabalho de IC na área de ciências exatas.

  14. A hybrid adaptive large neighborhood search heuristic for lot-sizing with setup times

    DEFF Research Database (Denmark)

    Muller, Laurent Flindt; Spoorendonk, Simon; Pisinger, David

    2012-01-01

    This paper presents a hybrid of a general heuristic framework and a general purpose mixed-integer programming (MIP) solver. The framework is based on local search and an adaptive procedure which chooses between a set of large neighborhoods to be searched. A mixed integer programming solver and its......, and the upper bounds found by the commercial MIP solver ILOG CPLEX using state-of-the-art MIP formulations. Furthermore, we improve the best known solutions on 60 out of 100 and improve the lower bound on all 100 instances from the literature...

  15. MUSiC. A model unspecific search in CMS based on 2010 LHC data

    Energy Technology Data Exchange (ETDEWEB)

    Pieta, Holger

    2012-06-20

    A Model Unspecific Search in CMS (MUSiC) is presented in this work, along with its results on the data taken in 2010 by the Compact Muon Solenoid (CMS) at the Large Hadron Collider (LHC). This analysis shows a sensitivity to various models for new physics and provides a broad view at the data, due to its minimal theoretical bias. Events are classified with respect to their reconstructed objects: Muons, electrons, photons, jets and missing transverse energy. Up to three kinematic variables in each of these classes are systematically scanned for continuous bin regions deviating significantly from the predictions by the Standard Model of particle physics. No deviations beyond expected fluctuations are observed, when taking systematic uncertainties into account. The sensitivity of the analysis to certain models beyond the Standard Model is demonstrated.

  16. A concept ideation framework for medical device design.

    Science.gov (United States)

    Hagedorn, Thomas J; Grosse, Ian R; Krishnamurty, Sundar

    2015-06-01

    Medical device design is a challenging process, often requiring collaboration between medical and engineering domain experts. This collaboration can be best institutionalized through systematic knowledge transfer between the two domains coupled with effective knowledge management throughout the design innovation process. Toward this goal, we present the development of a semantic framework for medical device design that unifies a large medical ontology with detailed engineering functional models along with the repository of design innovation information contained in the US Patent Database. As part of our development, existing medical, engineering, and patent document ontologies were modified and interlinked to create a comprehensive medical device innovation and design tool with appropriate properties and semantic relations to facilitate knowledge capture, enrich existing knowledge, and enable effective knowledge reuse for different scenarios. The result is a Concept Ideation Framework for Medical Device Design (CIFMeDD). Key features of the resulting framework include function-based searching and automated inter-domain reasoning to uniquely enable identification of functionally similar procedures, tools, and inventions from multiple domains based on simple semantic searches. The significance and usefulness of the resulting framework for aiding in conceptual design and innovation in the medical realm are explored via two case studies examining medical device design problems. Copyright © 2015 Elsevier Inc. All rights reserved.

  17. Idealized Simulations of a Squall Line from the MC3E Field Campaign Applying Three Bin Microphysics Schemes: Dynamic and Thermodynamic Structure

    Energy Technology Data Exchange (ETDEWEB)

    Xue, Lulin [National Center for Atmospheric Research, Boulder, Colorado; Fan, Jiwen [Pacific Northwest National Laboratory, Richland, Washington; Lebo, Zachary J. [University of Wyoming, Laramie, Wyoming; Wu, Wei [National Center for Atmospheric Research, Boulder, Colorado; University of Illinois at Urbana–Champaign, Urbana, Illinois; Morrison, Hugh [National Center for Atmospheric Research, Boulder, Colorado; Grabowski, Wojciech W. [National Center for Atmospheric Research, Boulder, Colorado; Chu, Xia [University of Wyoming, Laramie, Wyoming; Geresdi, István [University of Pécs, Pécs, Hungary; North, Kirk [McGill University, Montréal, Québec, Canada; Stenz, Ronald [University of North Dakota, Grand Forks, North Dakota; Gao, Yang [Pacific Northwest National Laboratory, Richland, Washington; Lou, Xiaofeng [Chinese Academy of Meteorological Sciences, Beijing, China; Bansemer, Aaron [National Center for Atmospheric Research, Boulder, Colorado; Heymsfield, Andrew J. [National Center for Atmospheric Research, Boulder, Colorado; McFarquhar, Greg M. [National Center for Atmospheric Research, Boulder, Colorado; University of Illinois at Urbana–Champaign, Urbana, Illinois; Rasmussen, Roy M. [National Center for Atmospheric Research, Boulder, Colorado

    2017-12-01

    The squall line event on May 20, 2011, during the Midlatitude Continental Convective Clouds (MC3E) field campaign has been simulated by three bin (spectral) microphysics schemes coupled into the Weather Research and Forecasting (WRF) model. Semi-idealized three-dimensional simulations driven by temperature and moisture profiles acquired by a radiosonde released in the pre-convection environment at 1200 UTC in Morris, Oklahoma show that each scheme produced a squall line with features broadly consistent with the observed storm characteristics. However, substantial differences in the details of the simulated dynamic and thermodynamic structure are evident. These differences are attributed to different algorithms and numerical representations of microphysical processes, assumptions of the hydrometeor processes and properties, especially ice particle mass, density, and terminal velocity relationships with size, and the resulting interactions between the microphysics, cold pool, and dynamics. This study shows that different bin microphysics schemes, designed to be conceptually more realistic and thus arguably more accurate than bulk microphysics schemes, still simulate a wide spread of microphysical, thermodynamic, and dynamic characteristics of a squall line, qualitatively similar to the spread of squall line characteristics using various bulk schemes. Future work may focus on improving the representation of ice particle properties in bin schemes to reduce this uncertainty and using the similar assumptions for all schemes to isolate the impact of physics from numerics.

  18. Beyond Ambiguity: A Practical Framework for Developing and Implementing Open Government Reforms

    Directory of Open Access Journals (Sweden)

    Merlin Chatwin

    2017-12-01

    Full Text Available The broad idea of ‘Open Government’ is widely accepted as a facilitator for rebuilding trust and validation in governments around the world. The Open Government Partnership is a significant driver of this movement with over 75 member nations, 15 subnational government participants and many others local governments implementing reforms within their national frameworks. The central tenets of transparency, accountability, participation, and collaboration are well understood within scholarly works and practitioner publications. However, open government is yet to be attributed with a universally acknowledged definition. This leads to questions of adaptability and salience of the concept of open government across diverse contexts. This paper addresses these questions by utilizing a human systems framework called the Dialogue Boxes. To develop an understanding of how open government is currently positioned within scholarly works and practitioner publications, an extensive literature search was conducted. The search utilized major search engines, often-cited references, direct journal searches and colleague provided references. Using existing definitions and descriptions, this paper populates the framework with available information and allow for context specific content to be populated by future users. Ultimately, the aim of the paper is to support the development of open government action plans that maximize the direct positive impact on people’s lives.

  19. IBRI-CASONTO: Ontology-based semantic search engine

    Directory of Open Access Journals (Sweden)

    Awny Sayed

    2017-11-01

    Full Text Available The vast availability of information, that added in a very fast pace, in the data repositories creates a challenge in extracting correct and accurate information. Which has increased the competition among developers in order to gain access to technology that seeks to understand the intent researcher and contextual meaning of terms. While the competition for developing an Arabic Semantic Search systems are still in their infancy, and the reason could be traced back to the complexity of Arabic Language. It has a complex morphological, grammatical and semantic aspects, as it is a highly inflectional and derivational language. In this paper, we try to highlight and present an Ontological Search Engine called IBRI-CASONTO for Colleges of Applied Sciences, Oman. Our proposed engine supports both Arabic and English language. It is also employed two types of search which are a keyword-based search and a semantics-based search. IBRI-CASONTO is based on different technologies such as Resource Description Framework (RDF data and Ontological graph. The experiments represent in two sections, first it shows a comparison among Entity-Search and the Classical-Search inside the IBRI-CASONTO itself, second it compares the Entity-Search of IBRI-CASONTO with currently used search engines, such as Kngine, Wolfram Alpha and the most popular engine nowadays Google, in order to measure their performance and efficiency.

  20. Narrative review of frameworks for translating research evidence into policy and practice

    Directory of Open Access Journals (Sweden)

    Ben Li

    2017-02-01

    Full Text Available Background: A significant challenge in research translation is that interested parties interpret and apply the associated terms and conceptual frameworks in different ways. The purpose of this review was to: a examine different research translation frameworks; b examine the similarities and differences between the frameworks; and c identify key strengths and weaknesses of the models when they are applied in practice. Methods: The review involved a keyword search of PubMed. The search string was (translational research OR knowledge translation OR evidence to practice AND (framework OR model OR theory AND (public health OR health promotion OR medicine. Included studies were published in English between January 1990 and December 2014, and described frameworks, models or theories associated with research translation. Results: The final review included 98 papers, and 41 different frameworks and models were identified. The most frequently applied knowledge translation framework in the literature was RE-AIM, followed by the knowledge translation continuum or ‘T’ models, the Knowledge to Action framework, the PARiHS framework, evidence based public health models, and the stages of research and evaluation model. Conclusion: The models identified in this review stem from different fields, including implementation science, basic and medical sciences, health services research and public health, and propose different but related pathways to closing the research–practice gap.

  1. BEACON: A Summary Framework to Overcome Potential Reimbursement Hurdles.

    Science.gov (United States)

    Dunlop, William C N; Mullins, C Daniel; Pirk, Olaf; Goeree, Ron; Postma, Maarten J; Enstone, Ashley; Heron, Louise

    2016-10-01

    To provide a framework for addressing payers' criteria during the development of pharmaceuticals. A conceptual framework was presented to an international health economic expert panel for discussion. A structured literature search (from 2010 to May 2015), using the following databases in Ovid: Medline(®) and Medline(®) In-Process (PubMed), Embase (Ovid), EconLit (EBSCOhost) and the National Health Service Economic Evaluation Database (NHS EED), and a 'grey literature' search, were conducted to identify existing criteria from the payer perspective. The criteria assessed by existing frameworks and guidelines were collated; the most commonly reported criteria were considered for inclusion in the framework. A mnemonic was conceived as a memory aide to summarise these criteria. Overall, 41 publications were identified as potentially relevant to the objective. Following further screening, 26 were excluded upon full-text review on the basis of no framework presented (n = 13), redundancy (n = 11) or abstract only (n = 2). Frameworks that captured criteria developed for or utilised by the pharmaceutical industry (n = 5) and reimbursement guidance (n = 10) were reviewed. The most commonly identified criteria-unmet need/patient burden, safety, efficacy, quality-of-life outcomes, environment, evidence quality, budget impact and comparator-were incorporated into the summary framework. For ease of communication, the following mnemonic was developed: BEACON (Burden/target population, Environment, Affordability/value, Comparator, Outcomes, Number of studies/quality of evidence). The BEACON framework aims to capture the 'essence' of payer requirements by addressing the most commonly described criteria requested by payers regarding the introduction of a new pharmaceutical.

  2. Morphological and Strength Properties of Tanjung Bin Coal Ash Mixtures for Applied in Geotechnical Engineering Work

    OpenAIRE

    Awang, Abd. Rahim; Marto, Aminaton; Makhtar, Ahmad Maher

    2012-01-01

    In Malaysia, coal has been used as a raw material to generate electricity since 1988. In the past, most of the wastage of coal burning especially the bottom ash was not managed properly as it was dumped in the waste pond and accumulated drastically.This paper focuses on some properties of coal ash mixtures (fly  ash and bottom ash mixtures) from Tanjung Bin power plant. The characteristics studied were morphological properties, compaction behaviour and strength properties. Strength properties...

  3. Charter Schools and the Teacher Job Search

    Science.gov (United States)

    Cannata, Marisa

    2011-01-01

    This article examines the position of charter schools in prospective elementary teachers' job search decisions. Using a labor market segmentation framework, it explores teacher applicants' decisions to apply to charter schools. The data come from a mixed-methods longitudinal study of prospective teachers looking for their first job. This article…

  4. A Hybrid Programming Framework for Modeling and Solving Constraint Satisfaction and Optimization Problems

    Directory of Open Access Journals (Sweden)

    Paweł Sitek

    2016-01-01

    Full Text Available This paper proposes a hybrid programming framework for modeling and solving of constraint satisfaction problems (CSPs and constraint optimization problems (COPs. Two paradigms, CLP (constraint logic programming and MP (mathematical programming, are integrated in the framework. The integration is supplemented with the original method of problem transformation, used in the framework as a presolving method. The transformation substantially reduces the feasible solution space. The framework automatically generates CSP and COP models based on current values of data instances, questions asked by a user, and set of predicates and facts of the problem being modeled, which altogether constitute a knowledge database for the given problem. This dynamic generation of dedicated models, based on the knowledge base, together with the parameters changing externally, for example, the user’s questions, is the implementation of the autonomous search concept. The models are solved using the internal or external solvers integrated with the framework. The architecture of the framework as well as its implementation outline is also included in the paper. The effectiveness of the framework regarding the modeling and solution search is assessed through the illustrative examples relating to scheduling problems with additional constrained resources.

  5. Annotating images by mining image search results.

    Science.gov (United States)

    Wang, Xin-Jing; Zhang, Lei; Li, Xirong; Ma, Wei-Ying

    2008-11-01

    Although it has been studied for years by the computer vision and machine learning communities, image annotation is still far from practical. In this paper, we propose a novel attempt at model-free image annotation, which is a data-driven approach that annotates images by mining their search results. Some 2.4 million images with their surrounding text are collected from a few photo forums to support this approach. The entire process is formulated in a divide-and-conquer framework where a query keyword is provided along with the uncaptioned image to improve both the effectiveness and efficiency. This is helpful when the collected data set is not dense everywhere. In this sense, our approach contains three steps: 1) the search process to discover visually and semantically similar search results, 2) the mining process to identify salient terms from textual descriptions of the search results, and 3) the annotation rejection process to filter out noisy terms yielded by Step 2. To ensure real-time annotation, two key techniques are leveraged-one is to map the high-dimensional image visual features into hash codes, the other is to implement it as a distributed system, of which the search and mining processes are provided as Web services. As a typical result, the entire process finishes in less than 1 second. Since no training data set is required, our approach enables annotating with unlimited vocabulary and is highly scalable and robust to outliers. Experimental results on both real Web images and a benchmark image data set show the effectiveness and efficiency of the proposed algorithm. It is also worth noting that, although the entire approach is illustrated within the divide-and conquer framework, a query keyword is not crucial to our current implementation. We provide experimental results to prove this.

  6. Implementing BosonSampling with time-bin encoding: Analysis of loss, mode mismatch, and time jitter

    Science.gov (United States)

    Motes, Keith R.; Dowling, Jonathan P.; Gilchrist, Alexei; Rohde, Peter P.

    2015-11-01

    It was recently shown by Motes, Gilchrist, Dowling, and Rohde [Phys. Rev. Lett. 113, 120501 (2014), 10.1103/PhysRevLett.113.120501] that a time-bin encoded fiber-loop architecture can implement an arbitrary passive linear optics transformation. This was shown in the case of an ideal scheme whereby the architecture has no sources of error. In any realistic implementation, however, physical errors are present, which corrupt the output of the transformation. We investigate the dominant sources of error in this architecture—loss and mode mismatch—and consider how it affects the BosonSampling protocol, a key application for passive linear optics. For our loss analysis we consider two major components that contribute to loss—fiber and switches—and calculate how this affects the success probability and fidelity of the device. Interestingly, we find that errors due to loss are not uniform (unique to time-bin encoding), which asymmetrically biases the implemented unitary. Thus loss necessarily limits the class of unitaries that may be implemented, and therefore future implementations must prioritize minimizing loss rates if arbitrary unitaries are to be implemented. Our formalism for mode mismatch is generalized to account for various phenomenon that may cause mode mismatch, but we focus on two—errors in fiber-loop lengths and time jitter of the photon source. These results provide a guideline for how well future experimental implementations might perform in light of these error mechanisms.

  7. Serendipity in dark photon searches

    Science.gov (United States)

    Ilten, Philip; Soreq, Yotam; Williams, Mike; Xue, Wei

    2018-06-01

    Searches for dark photons provide serendipitous discovery potential for other types of vector particles. We develop a framework for recasting dark photon searches to obtain constraints on more general theories, which includes a data-driven method for determining hadronic decay rates. We demonstrate our approach by deriving constraints on a vector that couples to the B-L current, a leptophobic B boson that couples directly to baryon number and to leptons via B- γ kinetic mixing, and on a vector that mediates a protophobic force. Our approach can easily be generalized to any massive gauge boson with vector couplings to the Standard Model fermions, and software to perform any such recasting is provided at https://gitlab.com/philten/darkcast https://gitlab.com/philten/darkcast" TargetType="URL"/> .

  8. Informal Versus Formal Search : Which Yields a Better Pay?

    OpenAIRE

    Semih Tumen

    2015-01-01

    Estimates on the effect of job contact method – i.e., informal versus formal search – on wage offers vary considerably across studies, with some of them finding a positive correlation between getting help from informal connections and obtaining high-paying jobs, while others finding a negative one. In this paper, I theoretically investigate the sources of discrepancies in these empirical results. Using a formal job search framework, I derive an equilibrium wage distribution which reveals that...

  9. A lifelong learning hyper-heuristic method for bin packing.

    Science.gov (United States)

    Sim, Kevin; Hart, Emma; Paechter, Ben

    2015-01-01

    We describe a novel hyper-heuristic system that continuously learns over time to solve a combinatorial optimisation problem. The system continuously generates new heuristics and samples problems from its environment; and representative problems and heuristics are incorporated into a self-sustaining network of interacting entities inspired by methods in artificial immune systems. The network is plastic in both its structure and content, leading to the following properties: it exploits existing knowledge captured in the network to rapidly produce solutions; it can adapt to new problems with widely differing characteristics; and it is capable of generalising over the problem space. The system is tested on a large corpus of 3,968 new instances of 1D bin-packing problems as well as on 1,370 existing problems from the literature; it shows excellent performance in terms of the quality of solutions obtained across the datasets and in adapting to dynamically changing sets of problem instances compared to previous approaches. As the network self-adapts to sustain a minimal repertoire of both problems and heuristics that form a representative map of the problem space, the system is further shown to be computationally efficient and therefore scalable.

  10. Looking at large data sets using binned data plots

    Energy Technology Data Exchange (ETDEWEB)

    Carr, D.B.

    1990-04-01

    This report addresses the monumental challenge of developing exploratory analysis methods for large data sets. The goals of the report are to increase awareness of large data sets problems and to contribute simple graphical methods that address some of the problems. The graphical methods focus on two- and three-dimensional data and common task such as finding outliers and tail structure, assessing central structure and comparing central structures. The methods handle large sample size problems through binning, incorporate information from statistical models and adapt image processing algorithms. Examples demonstrate the application of methods to a variety of publicly available large data sets. The most novel application addresses the too many plots to examine'' problem by using cognostics, computer guiding diagnostics, to prioritize plots. The particular application prioritizes views of computational fluid dynamics solution sets on the fly. That is, as each time step of a solution set is generated on a parallel processor the cognostics algorithms assess virtual plots based on the previous time step. Work in such areas is in its infancy and the examples suggest numerous challenges that remain. 35 refs., 15 figs.

  11. Searches for Charginos and Neutralinos with the D0 Detector

    International Nuclear Information System (INIS)

    Adams, T.

    2009-01-01

    Within the framework of supersymmetry, charginos and/or neutralinos are often the preferred topics of searches for experimental evidence. This is due to the facts that in much of parameter space they are the lightest supersymmetric partners and they offer unique final states to separate from standard model backgrounds. The D0 experiment has performed several recent searches including the traditional trilepton final state and a decay chain involving dark photons

  12. OERScout Technology Framework: A Novel Approach to Open Educational Resources Search

    Science.gov (United States)

    Abeywardena, Ishan Sudeera; Chan, Chee Seng; Tham, Choy Yoong

    2013-01-01

    The open educational resources (OER) movement has gained momentum in the past few years. With this new drive towards making knowledge open and accessible, a large number of OER repositories have been established and made available online throughout the world. However, the inability of existing search engines such as Google, Yahoo!, and Bing to…

  13. An Adaptive Large Neighborhood Search Algorithm for the Resource-constrained Project Scheduling Problem

    DEFF Research Database (Denmark)

    Muller, Laurent Flindt

    2009-01-01

    We present an application of an Adaptive Large Neighborhood Search (ALNS) algorithm to the Resource-constrained Project Scheduling Problem (RCPSP). The ALNS framework was first proposed by Pisinger and Røpke [19] and can be described as a large neighborhood search algorithm with an adaptive layer......, where a set of destroy/repair neighborhoods compete to modify the current solution in each iteration of the algorithm. Experiments are performed on the wellknown J30, J60 and J120 benchmark instances, which show that the proposed algorithm is competitive and confirms the strength of the ALNS framework...

  14. Dismantlement and removal of Old Hydrofracture Facility bulk storage bins and water tank, Oak Ridge National Laboratory, Oak Ridge, Tennessee

    International Nuclear Information System (INIS)

    1998-03-01

    The Old Hydrofracture Facility (OHF), located at Oak Ridge National Laboratory (ORNL), was constructed in 1963 to allow experimentation and operations with an integrated solid storage, mixing, and grout injection facility. During its operation, OHF blended liquid low-level waste with grout and used a hydrofracture process to pump the waste into a deep low-permeable shale formation. Since the OHF Facility was taken out of service in 1980, the four bulk storage bins located adjacent to Building 7852 had deteriorated to the point that they were a serious safety hazard. The ORNL Surveillance and Maintenance Program requested and received permission from the US Department of Energy to dismantle the bins as a maintenance action and send the free-released metal to an approved scrap metal vendor. A 25,000-gal stainless steel water tank located at the OHF site was included in the scope. A fixed-price subcontract was signed with Allied Technology Group, Inc., to remove the four bulk storage bins and water tank to a staging area where certified Health Physics personnel could survey, segregate, package, and send the radiologically clean scrap metal to an approved scrap metal vendor. All radiologically contaminated metal and metal that could not be surveyed was packaged and staged for later disposal. Permissible personnel exposure limits were not exceeded, no injuries were incurred, and no health and safety violations occurred throughout the duration of the project. Upon completion of the dismantlement, the project had generated 53,660 lb of clean scrap metal (see Appendix D). This resulted in $3,410 of revenue generated and a cost avoidance of an estimated $100,000 in waste disposal fees

  15. Update on CERN Search based on SharePoint 2013

    Science.gov (United States)

    Alvarez, E.; Fernandez, S.; Lossent, A.; Posada, I.; Silva, B.; Wagner, A.

    2017-10-01

    CERN’s enterprise Search solution “CERN Search” provides a central search solution for users and CERN service providers. A total of about 20 million public and protected documents from a wide range of document collections is indexed, including Indico, TWiki, Drupal, SharePoint, JACOW, E-group archives, EDMS, and CERN Web pages. In spring 2015, CERN Search was migrated to a new infrastructure based on SharePoint 2013. In the context of this upgrade, the document pre-processing and indexing process was redesigned and generalised. The new data feeding framework allows to profit from new functionality and it facilitates the long term maintenance of the system.

  16. Towards Semantic Search and Inference in Electronic Medical Records

    Directory of Open Access Journals (Sweden)

    Bevan Koopman

    2012-09-01

    Full Text Available Background This paper presents a novel approach to searching electronic medical records that is based on concept matching rather than keyword matching. Aims The concept-based approach is intended to overcome specific challenges we identified in searching medical records. Method Queries and documents were transformed from their term-based originals into medical concepts as defined by the SNOMED-CT ontology. Results Evaluation on a real-world collection of medical records showed our concept-based approach outperformed a keyword baseline by 25% in Mean Average Precision. Conclusion The concept-based approach provides a framework for further development of inference based search systems for dealing with medical data.

  17. Modified strip packing heuristics for the rectangular variable-sized bin packing problem

    Directory of Open Access Journals (Sweden)

    FG Ortmann

    2010-06-01

    Full Text Available Two packing problems are considered in this paper, namely the well-known strip packing problem (SPP and the variable-sized bin packing problem (VSBPP. A total of 252 strip packing heuristics (and variations thereof from the literature, as well as novel heuristics proposed by the authors, are compared statistically by means of 1170 SPP benchmark instances in order to identify the best heuristics in various classes. A combination of new heuristics with a new sorting method yields the best results. These heuristics are combined with a previous heuristic for the VSBPP by the authors to find good feasible solutions to 1357 VSBPP benchmark instances. This is the largest statistical comparison of algorithms for the SPP and the VSBPP to the best knowledge of the authors.

  18. Development of a Novel Therapeutic Paradigm Utilizing a Mammary Gland-Targeted, Bin-1 Knockout Mouse Model

    Science.gov (United States)

    2007-03-01

    Thierry-Mieg et al. AceView: identification and functional annotation of cDNA- supported genes in higher organisms— Homo sapiens gene INDO, encoding...stimulating function of RhoB. J Biol Chem 1997; 272:15591–4. 25. Routhier EL , Donover PS, Prendergast GC. hob1+, the homolog of Bin1 in fission yeast, is...tumours on inoculation of EL -4 thymoma or B16 melanoma cells due to an increased tumour-specific CTL response85. TGFβ suppression of tumour-specific

  19. The Search for Peace in Mindanao: Resolving a Wicked Problem

    Science.gov (United States)

    2012-03-22

    negotiating panel, still led by Mohagher Iqbal, but with new members such as Professor Abhoud Syed Linga and Datu Antonio Kinoc of B‘laan tribe...that the MILF received funds from charitable institutions operated by Mohammed Jamal Khalifa, Osama Bin Laden‘s brother-in-law.53 The MILF has...Crucible: A Reader (Quezon City: CenPeg Publications), 2008, p. 136. 19 7 Hermoso, p. 61. 8 Dato‘ Md Ismael bin Ahmad Khan, ―The International

  20. Standardized mappings--a framework to combine different semantic mappers into a standardized web-API.

    Science.gov (United States)

    Neuhaus, Philipp; Doods, Justin; Dugas, Martin

    2015-01-01

    Automatic coding of medical terms is an important, but highly complicated and laborious task. To compare and evaluate different strategies a framework with a standardized web-interface was created. Two UMLS mapping strategies are compared to demonstrate the interface. The framework is a Java Spring application running on a Tomcat application server. It accepts different parameters and returns results in JSON format. To demonstrate the framework, a list of medical data items was mapped by two different methods: similarity search in a large table of terminology codes versus search in a manually curated repository. These mappings were reviewed by a specialist. The evaluation shows that the framework is flexible (due to standardized interfaces like HTTP and JSON), performant and reliable. Accuracy of automatically assigned codes is limited (up to 40%). Combining different semantic mappers into a standardized Web-API is feasible. This framework can be easily enhanced due to its modular design.

  1. Specification Search for Identifying the Correct Mean Trajectory in Polynomial Latent Growth Models

    Science.gov (United States)

    Kim, Minjung; Kwok, Oi-Man; Yoon, Myeongsun; Willson, Victor; Lai, Mark H. C.

    2016-01-01

    This study investigated the optimal strategy for model specification search under the latent growth modeling (LGM) framework, specifically on searching for the correct polynomial mean or average growth model when there is no a priori hypothesized model in the absence of theory. In this simulation study, the effectiveness of different starting…

  2. Service quality framework for clinical laboratories.

    Science.gov (United States)

    Ramessur, Vinaysing; Hurreeram, Dinesh Kumar; Maistry, Kaylasson

    2015-01-01

    The purpose of this paper is to illustrate a service quality framework that enhances service delivery in clinical laboratories by gauging medical practitioner satisfaction and by providing avenues for continuous improvement. The case study method has been used for conducting the exploratory study, with focus on the Mauritian public clinical laboratory. A structured questionnaire based on the SERVQUAL service quality model was used for data collection, analysis and for the development of the service quality framework. The study confirms the pertinence of the following service quality dimensions within the context of clinical laboratories: tangibility, reliability, responsiveness, turnaround time, technology, test reports, communication and laboratory staff attitude and behaviour. The service quality framework developed, termed LabSERV, is vital for clinical laboratories in the search for improving service delivery to medical practitioners. This is a pioneering work carried out in the clinical laboratory sector in Mauritius. Medical practitioner expectations and perceptions have been simultaneously considered to generate a novel service quality framework for clinical laboratories.

  3. A framework and methodology for navigating disaster and global health in crisis literature.

    Science.gov (United States)

    Chan, Jennifer L; Burkle, Frederick M

    2013-04-04

    Both 'disasters' and 'global health in crisis' research has dramatically grown due to the ever-increasing frequency and magnitude of crises around the world. Large volumes of peer-reviewed literature are not only a testament to the field's value and evolution, but also present an unprecedented outpouring of seemingly unmanageable information across a wide array of crises and disciplines. Disaster medicine, health and humanitarian assistance, global health and public health disaster literature all lie within the disaster and global health in crisis literature spectrum and are increasingly accepted as multidisciplinary and transdisciplinary disciplines. Researchers, policy makers, and practitioners now face a new challenge; that of accessing this expansive literature for decision-making and exploring new areas of research. Individuals are also reaching beyond the peer-reviewed environment to grey literature using search engines like Google Scholar to access policy documents, consensus reports and conference proceedings. What is needed is a method and mechanism with which to search and retrieve relevant articles from this expansive body of literature. This manuscript presents both a framework and workable process for a diverse group of users to navigate the growing peer-reviewed and grey disaster and global health in crises literature. Disaster terms from textbooks, peer-reviewed and grey literature were used to design a framework of thematic clusters and subject matter 'nodes'. A set of 84 terms, selected from 143 curated terms was organized within each node reflecting topics within the disaster and global health in crisis literature. Terms were crossed with one another and the term 'disaster'. The results were formatted into tables and matrices. This process created a roadmap of search terms that could be applied to the PubMed database. Each search in the matrix or table results in a listed number of articles. This process was applied to literature from PubMed from

  4. Data-driven model-independent searches for long-lived particles at the LHC

    Science.gov (United States)

    Coccaro, Andrea; Curtin, David; Lubatti, H. J.; Russell, Heather; Shelton, Jessie

    2016-12-01

    Neutral long-lived particles (LLPs) are highly motivated by many beyond the Standard Model scenarios, such as theories of supersymmetry, baryogenesis, and neutral naturalness, and present both tremendous discovery opportunities and experimental challenges for the LHC. A major bottleneck for current LLP searches is the prediction of Standard Model backgrounds, which are often impossible to simulate accurately. In this paper, we propose a general strategy for obtaining differential, data-driven background estimates in LLP searches, thereby notably extending the range of LLP masses and lifetimes that can be discovered at the LHC. We focus on LLPs decaying in the ATLAS muon system, where triggers providing both signal and control samples are available at LHC run 2. While many existing searches require two displaced decays, a detailed knowledge of backgrounds will allow for very inclusive searches that require just one detected LLP decay. As we demonstrate for the h →X X signal model of LLP pair production in exotic Higgs decays, this results in dramatic sensitivity improvements for proper lifetimes ≳10 m . In theories of neutral naturalness, this extends reach to glueball masses far below the b ¯b threshold. Our strategy readily generalizes to other signal models and other detector subsystems. This framework therefore lends itself to the development of a systematic, model-independent LLP search program, in analogy to the highly successful simplified-model framework of prompt searches.

  5. Agent-Based Data Integration Framework

    Directory of Open Access Journals (Sweden)

    Łukasz Faber

    2014-01-01

    Full Text Available Combining data from diverse, heterogeneous sources while facilitating a unified access to it is an important (albeit difficult task. There are various possibilities of performing it. In this publication, we propose and describe an agent-based framework dedicated to acquiring and processing distributed, heterogeneous data collected from diverse sources (e.g., the Internet, external software, relational, and document databases. Using this multi-agent-based approach in the aspects of the general architecture (the organization and management of the framework, we create a proof-of-concept implementation. The approach is presented using a sample scenario in which the system is used to search for personal and professional profiles of scientists.

  6. Directed area search using socio-biological vision algorithms and cognitive Bayesian reasoning

    Science.gov (United States)

    Medasani, S.; Owechko, Y.; Allen, D.; Lu, T. C.; Khosla, D.

    2010-04-01

    Volitional search systems that assist the analyst by searching for specific targets or objects such as vehicles, factories, airports, etc in wide area overhead imagery need to overcome multiple problems present in current manual and automatic approaches. These problems include finding targets hidden in terabytes of information, relatively few pixels on targets, long intervals between interesting regions, time consuming analysis requiring many analysts, no a priori representative examples or templates of interest, detecting multiple classes of objects, and the need for very high detection rates and very low false alarm rates. This paper describes a conceptual analyst-centric framework that utilizes existing technology modules to search and locate occurrences of targets of interest (e.g., buildings, mobile targets of military significance, factories, nuclear plants, etc.), from video imagery of large areas. Our framework takes simple queries from the analyst and finds the queried targets with relatively minimum interaction from the analyst. It uses a hybrid approach that combines biologically inspired bottom up attention, socio-biologically inspired object recognition for volitionally recognizing targets, and hierarchical Bayesian networks for modeling and representing the domain knowledge. This approach has the benefits of high accuracy, low false alarm rate and can handle both low-level visual information and high-level domain knowledge in a single framework. Such a system would be of immense help for search and rescue efforts, intelligence gathering, change detection systems, and other surveillance systems.

  7. Evaluating a federated medical search engine: tailoring the methodology and reporting the evaluation outcomes.

    Science.gov (United States)

    Saparova, D; Belden, J; Williams, J; Richardson, B; Schuster, K

    2014-01-01

    Federated medical search engines are health information systems that provide a single access point to different types of information. Their efficiency as clinical decision support tools has been demonstrated through numerous evaluations. Despite their rigor, very few of these studies report holistic evaluations of medical search engines and even fewer base their evaluations on existing evaluation frameworks. To evaluate a federated medical search engine, MedSocket, for its potential net benefits in an established clinical setting. This study applied the Human, Organization, and Technology (HOT-fit) evaluation framework in order to evaluate MedSocket. The hierarchical structure of the HOT-factors allowed for identification of a combination of efficiency metrics. Human fit was evaluated through user satisfaction and patterns of system use; technology fit was evaluated through the measurements of time-on-task and the accuracy of the found answers; and organization fit was evaluated from the perspective of system fit to the existing organizational structure. Evaluations produced mixed results and suggested several opportunities for system improvement. On average, participants were satisfied with MedSocket searches and confident in the accuracy of retrieved answers. However, MedSocket did not meet participants' expectations in terms of download speed, access to information, and relevance of the search results. These mixed results made it necessary to conclude that in the case of MedSocket, technology fit had a significant influence on the human and organization fit. Hence, improving technological capabilities of the system is critical before its net benefits can become noticeable. The HOT-fit evaluation framework was instrumental in tailoring the methodology for conducting a comprehensive evaluation of the search engine. Such multidimensional evaluation of the search engine resulted in recommendations for system improvement.

  8. Making Temporal Search More Central in Spatial Data Infrastructures

    Science.gov (United States)

    Corti, P.; Lewis, B.

    2017-10-01

    A temporally enabled Spatial Data Infrastructure (SDI) is a framework of geospatial data, metadata, users, and tools intended to provide an efficient and flexible way to use spatial information which includes the historical dimension. One of the key software components of an SDI is the catalogue service which is needed to discover, query, and manage the metadata. A search engine is a software system capable of supporting fast and reliable search, which may use any means necessary to get users to the resources they need quickly and efficiently. These techniques may include features such as full text search, natural language processing, weighted results, temporal search based on enrichment, visualization of patterns in distributions of results in time and space using temporal and spatial faceting, and many others. In this paper we will focus on the temporal aspects of search which include temporal enrichment using a time miner - a software engine able to search for date components within a larger block of text, the storage of time ranges in the search engine, handling historical dates, and the use of temporal histograms in the user interface to display the temporal distribution of search results.

  9. Grandezas excesso de soluções líquidas binárias de glicóis + água a diferentes temperaturas e pressão atmosférica

    OpenAIRE

    Heloisa Emi Hoga

    2015-01-01

    Resumo: Propriedades excesso têm sido um caminho qualitativo e quantitativo para predizer o desvio da idealidade de soluções líquidas binárias. Além disso, as grandezas excesso têm sido usadas para desenvolver modelos e novas teorias de soluções. Neste trabalho teve como objetivo o estudo experimental de grandezas volumétricas, viscosimétricas, acústicas e das entalpias excesso de soluções líquidas binárias de água + etanol, ou + etileno glicol, ou + dietileno glicol, ou + trietileno glicol, ...

  10. Constraint-Based Local Search for Constrained Optimum Paths Problems

    Science.gov (United States)

    Pham, Quang Dung; Deville, Yves; van Hentenryck, Pascal

    Constrained Optimum Path (COP) problems arise in many real-life applications and are ubiquitous in communication networks. They have been traditionally approached by dedicated algorithms, which are often hard to extend with side constraints and to apply widely. This paper proposes a constraint-based local search (CBLS) framework for COP applications, bringing the compositionality, reuse, and extensibility at the core of CBLS and CP systems. The modeling contribution is the ability to express compositional models for various COP applications at a high level of abstraction, while cleanly separating the model and the search procedure. The main technical contribution is a connected neighborhood based on rooted spanning trees to find high-quality solutions to COP problems. The framework, implemented in COMET, is applied to Resource Constrained Shortest Path (RCSP) problems (with and without side constraints) and to the edge-disjoint paths problem (EDP). Computational results show the potential significance of the approach.

  11. Interpretation of Higgs and Susy searches in MSUGRA and GMSB Models

    International Nuclear Information System (INIS)

    Vivie, J.B. de

    1999-10-01

    HIGGS and SUSY searches performed by the ALEPH Experiment at LEP are interpreted in the framework of two constrained R-parity conserving models: Minimal Supergravity and minimal Gauge Mediated Supersymmetry Breaking. (author)

  12. Unbinned likelihood maximisation framework for neutrino clustering in Python

    Energy Technology Data Exchange (ETDEWEB)

    Coenders, Stefan [Technische Universitaet Muenchen, Boltzmannstr. 2, 85748 Garching (Germany)

    2016-07-01

    Albeit having detected an astrophysical neutrino flux with IceCube, sources of astrophysical neutrinos remain hidden up to now. A detection of a neutrino point source is a smoking gun for hadronic processes and acceleration of cosmic rays. The search for neutrino sources has many degrees of freedom, for example steady versus transient, point-like versus extended sources, et cetera. Here, we introduce a Python framework designed for unbinned likelihood maximisations as used in searches for neutrino point sources by IceCube. Implementing source scenarios in a modular way, likelihood searches on various kinds can be implemented in a user-friendly way, without sacrificing speed and memory management.

  13. Short communication. Economics of natural resources: in search of a unified theoretical framework

    Energy Technology Data Exchange (ETDEWEB)

    Romero, C.

    2012-11-01

    This paper proposes a unified theoretical framework for dealing with the optimum economic use of any type of natural resource. After formulating and economically interpreting the unified framework, the basic rules governing the economic exploitation of the different natural resources can be easily obtained by particularizing the different values of its basic parameters. Taking this approach, it is easy to understand what commonalities there are, in terms of economic logic, between the different types of natural resources. This considerably increases the amount of consilience and understanding about the discipline. (Author) 8 refs.

  14. Guided search for triple conjunctions.

    Science.gov (United States)

    Nordfang, Maria; Wolfe, Jeremy M

    2014-08-01

    A key tenet of feature integration theory and of related theories such as guided search (GS) is that the binding of basic features requires attention. This would seem to predict that conjunctions of features of objects that have not been attended should not influence search. However, Found (1998) reported that an irrelevant feature (size) improved the efficiency of search for a Color × Orientation conjunction if it was correlated with the other two features across the display, as compared to the case in which size was not correlated with color and orientation features. We examined this issue with somewhat different stimuli. We used triple conjunctions of color, orientation, and shape (e.g., search for a red, vertical, oval-shaped item). This allowed us to manipulate the number of features that each distractor shared with the target (sharing) and it allowed us to vary the total number of distractor types (and, thus, the number of groups of identical items: grouping). We found that these triple conjunction searches were generally very efficient--producing very shallow Reaction Time × Set Size slopes, consistent with strong guidance by basic features. Nevertheless, both of the variables, sharing and grouping, modulated performance. These influences were not predicted by previous accounts of GS; however, both can be accommodated in a GS framework. Alternatively, it is possible, though not necessary, to see these effects as evidence for "preattentive binding" of conjunctions.

  15. Fine Physical Bin Mapping of the Powdery Mildew Resistance Gene Pm21 Based on Chromosomal Structural Variations in Wheat

    Directory of Open Access Journals (Sweden)

    Shanying Zhu

    2018-02-01

    Full Text Available Pm21, derived from wheat wild relative Dasypyrum villosum, is one of the most effective powdery mildew resistance genes and has been widely applied in wheat breeding in China. Mapping and cloning Pm21 are of importance for understanding its resistance mechanism. In the present study, physical mapping was performed using different genetic stocks involving in structural variations of chromosome 6VS carrying Pm21. The data showed that 6VS could be divided into eight distinguishable chromosomal bins, and Pm21 was mapped to the bin FLb4–b5/b6 closely flanked by the markers 6VS-08.6 and 6VS-10.2. Comparative genomic mapping indicated that the orthologous regions of FLb4–b5/b6 carrying Pm21 were narrowed to a 117.7 kb genomic region harboring 19 genes in Brachypodium and a 37.7 kb region harboring 5 genes in rice, respectively. The result was consistent with that given by recent genetic mapping in diploid D. villosum. In conclusion, this study demonstrated that physical mapping based on chromosomal structural variations is an efficient method for locating alien genes in wheat background.

  16. Visibiome: an efficient microbiome search engine based on a scalable, distributed architecture.

    Science.gov (United States)

    Azman, Syafiq Kamarul; Anwar, Muhammad Zohaib; Henschel, Andreas

    2017-07-24

    Given the current influx of 16S rRNA profiles of microbiota samples, it is conceivable that large amounts of them eventually are available for search, comparison and contextualization with respect to novel samples. This process facilitates the identification of similar compositional features in microbiota elsewhere and therefore can help to understand driving factors for microbial community assembly. We present Visibiome, a microbiome search engine that can perform exhaustive, phylogeny based similarity search and contextualization of user-provided samples against a comprehensive dataset of 16S rRNA profiles environments, while tackling several computational challenges. In order to scale to high demands, we developed a distributed system that combines web framework technology, task queueing and scheduling, cloud computing and a dedicated database server. To further ensure speed and efficiency, we have deployed Nearest Neighbor search algorithms, capable of sublinear searches in high-dimensional metric spaces in combination with an optimized Earth Mover Distance based implementation of weighted UniFrac. The search also incorporates pairwise (adaptive) rarefaction and optionally, 16S rRNA copy number correction. The result of a query microbiome sample is the contextualization against a comprehensive database of microbiome samples from a diverse range of environments, visualized through a rich set of interactive figures and diagrams, including barchart-based compositional comparisons and ranking of the closest matches in the database. Visibiome is a convenient, scalable and efficient framework to search microbiomes against a comprehensive database of environmental samples. The search engine leverages a popular but computationally expensive, phylogeny based distance metric, while providing numerous advantages over the current state of the art tool.

  17. BinCat: a Catalog of Nearby Binary Stars with Tools for Calculating Light-Leakage for Direct Imaging Missions

    Science.gov (United States)

    Holte, Elias Peter; Sirbu, Dan; Belikov, Ruslan

    2018-01-01

    Binary stars have been largely left out of direct imaging surveys for exoplanets, specifically for earth-sized planets in their star's habitable zone. Utilizing new direct imaging techniques brings us closer to being able to detect earth-like exoplanets around binary stars. In preparation for the upcoming WFIRST mission and other direct imaging-capable missions (HabEx, LUVIOR) it is important to understand the expected science yield resulting from the implementation of these imaging techniques. BinCat is a catalog of binary systems within 30 parsecs to be used as a target list for future direct imaging missions. There is a non-static component along with BinCat that allows researchers to predict the expected light-leakage between a binary component and its off-axis companion (a value critical to the aforementioned techniques) at any epoch. This is accomplished by using orbital elements from the Sixth Orbital Catalog to model the orbits of the binaries. The software was validated against the historical data used to generate the orbital parameters. When orbital information is unknown or the binaries are purely optical the proper motion of the pair taken from the Washington Double Star catalog is integrated in time to estimate expected light-leakage.

  18. Movable geometry and eigenvalue search capability in the MC21 Monte Carlo code

    International Nuclear Information System (INIS)

    Gill, D. F.; Nease, B. R.; Griesheimer, D. P.

    2013-01-01

    A description of a robust and flexible movable geometry implementation in the Monte Carlo code MC21 is described along with a search algorithm that can be used in conjunction with the movable geometry capability to perform eigenvalue searches based on the position of some geometric component. The natural use of the combined movement and search capability is searching to critical through variation of control rod (or control drum) position. The movable geometry discussion provides the mathematical framework for moving surfaces in the MC21 combinatorial solid geometry description. A discussion of the interface between the movable geometry system and the user is also described, particularly the ability to create a hierarchy of movable groups. Combined with the hierarchical geometry description in MC21 the movable group framework provides a very powerful system for inline geometry modification. The eigenvalue search algorithm implemented in MC21 is also described. The foundations of this algorithm are a regula falsi search though several considerations are made in an effort to increase the efficiency of the algorithm for use with Monte Carlo. Specifically, criteria are developed to determine after each batch whether the Monte Carlo calculation should be continued, the search iteration can be rejected, or the search iteration has converged. These criteria seek to minimize the amount of time spent per iteration. Results for the regula falsi method are shown, illustrating that the method as implemented is indeed convergent and that the optimizations made ultimately reduce the total computational expense. (authors)

  19. Movable geometry and eigenvalue search capability in the MC21 Monte Carlo code

    Energy Technology Data Exchange (ETDEWEB)

    Gill, D. F.; Nease, B. R.; Griesheimer, D. P. [Bettis Atomic Power Laboratory, PO Box 79, West Mifflin, PA 15122 (United States)

    2013-07-01

    A description of a robust and flexible movable geometry implementation in the Monte Carlo code MC21 is described along with a search algorithm that can be used in conjunction with the movable geometry capability to perform eigenvalue searches based on the position of some geometric component. The natural use of the combined movement and search capability is searching to critical through variation of control rod (or control drum) position. The movable geometry discussion provides the mathematical framework for moving surfaces in the MC21 combinatorial solid geometry description. A discussion of the interface between the movable geometry system and the user is also described, particularly the ability to create a hierarchy of movable groups. Combined with the hierarchical geometry description in MC21 the movable group framework provides a very powerful system for inline geometry modification. The eigenvalue search algorithm implemented in MC21 is also described. The foundations of this algorithm are a regula falsi search though several considerations are made in an effort to increase the efficiency of the algorithm for use with Monte Carlo. Specifically, criteria are developed to determine after each batch whether the Monte Carlo calculation should be continued, the search iteration can be rejected, or the search iteration has converged. These criteria seek to minimize the amount of time spent per iteration. Results for the regula falsi method are shown, illustrating that the method as implemented is indeed convergent and that the optimizations made ultimately reduce the total computational expense. (authors)

  20. Submillimeter wave spectroscopy of ethyl isocyanide and its searches in Orion

    Science.gov (United States)

    Margulès, L.; Tercero, B.; Guillemin, J. C.; Motiyenko, R. A.; Cernicharo, J.

    2018-02-01

    Context. About 40 cyanide compounds have been detected in the interstellar medium, but only 3 examples of organic isocyanide compounds were observed in this medium. Ethyl isocyanide is one of the best candidates for possible detection. Aim. To date, measurements of rotational spectra are limited to 40 GHz. The extrapolation of the prediction in the millimeter wave domain is inaccurate and does not permit an unambiguous detection. Methods: The rotational spectra were reinvestigated from 0.15 to 1 THz. Using the new prediction, we searched for the compound ethyl isocyanide in Orion KL and Sgr B2. Results: We newly assigned 2906 transitions and fitted these new data with those from previous studies, reaching quantum numbers up to J = 103 and Ka = 30. The asymmetric top Hamiltonian proposed by Watson in the Ir representation was used for the analysis, and both reductions A and S were tested. The search for CH3CH2NC in Sgr B2 (IRAM 30m) and Orion KL (IRAM 30m, ALMA Science Verification) result in a non-detection; upper limits to the column density were derived. Tables S1-S4 are only available at the CDS via anonymous ftp to http://cdsarc.u-strasbg.fr (http://130.79.128.5) or via http://cdsarc.u-strasbg.fr/viz-bin/qcat?J/A+A/610/A44

  1. An Effective Framework For Economic Dispatch Using Modified Harmony Search Algorithm

    Directory of Open Access Journals (Sweden)

    Advik Kumar

    2017-09-01

    Full Text Available The effects of ever-increasing wind power generation for solving the economic dispatch ED problem have led to high penetration of renewable energy source in new power systems. Continuing search for better utilizing of wind turbine associated with thermal sources to find the optimal allocation of output power is necessary in which pro-vide more reliability and efficiency. Dynamic nature of wind energy has imposed uncertainties characteristics in the poser systems. To deal with this problem an effective probabilistic method to investigate all unpredictability would be a good idea to make more realistic analysis. This paper presents a heuristics optimization method based on harmony search HS algorithm to solve non-convex ED problems while uncertainties effects caused by wind turbines are considered. To involve a realistic analysis as a more practical investigation the proposed probabilistic ED PED approach includes prohibited operating zone POZ system spinning reserve ramp rate limits variety of fuel is considered in this studies. Point Estimate Method PEM as a proposed PED model the uncertainties of wind speed for wind turbines to present better realization to the problem. Optimal solution are presented for vari-ous test system and these solutions demonstrate the benefits of our approach in terms of cost over existing ED techniques.

  2. DISCRN: A Distributed Storytelling Framework for Intelligence Analysis.

    Science.gov (United States)

    Shukla, Manu; Dos Santos, Raimundo; Chen, Feng; Lu, Chang-Tien

    2017-09-01

    Storytelling connects entities (people, organizations) using their observed relationships to establish meaningful storylines. This can be extended to spatiotemporal storytelling that incorporates locations, time, and graph computations to enhance coherence and meaning. But when performed sequentially these computations become a bottleneck because the massive number of entities make space and time complexity untenable. This article presents DISCRN, or distributed spatiotemporal ConceptSearch-based storytelling, a distributed framework for performing spatiotemporal storytelling. The framework extracts entities from microblogs and event data, and links these entities using a novel ConceptSearch to derive storylines in a distributed fashion utilizing key-value pair paradigm. Performing these operations at scale allows deeper and broader analysis of storylines. The novel parallelization techniques speed up the generation and filtering of storylines on massive datasets. Experiments with microblog posts such as Twitter data and Global Database of Events, Language, and Tone events show the efficiency of the techniques in DISCRN.

  3. Adaptation of the modified Bouc–Wen model to compensate for hysteresis in respiratory motion for the list-mode binning of cardiac SPECT and PET acquisitions: Testing using MRI

    International Nuclear Information System (INIS)

    Dasari, Paul K. R.; Shazeeb, Mohammed Salman; Könik, Arda; Lindsay, Clifford; Mukherjee, Joyeeta M.; Johnson, Karen L.; King, Michael A.

    2014-01-01

    Purpose: Binning list-mode acquisitions as a function of a surrogate signal related to respiration has been employed to reduce the impact of respiratory motion on image quality in cardiac emission tomography (SPECT and PET). Inherent in amplitude binning is the assumption that there is a monotonic relationship between the amplitude of the surrogate signal and respiratory motion of the heart. This assumption is not valid in the presence of hysteresis when heart motion exhibits a different relationship with the surrogate during inspiration and expiration. The purpose of this study was to investigate the novel approach of using the Bouc–Wen (BW) model to provide a signal accounting for hysteresis when binning list-mode data with the goal of thereby improving motion correction. The study is based on the authors’ previous observations that hysteresis between chest and abdomen markers was indicative of hysteresis between abdomen markers and the internal motion of the heart. Methods: In 19 healthy volunteers, they determined the internal motion of the heart and diaphragm in the superior–inferior direction during free breathing using MRI navigators. A visual tracking system (VTS) synchronized with MRI acquisition tracked the anterior–posterior motions of external markers placed on the chest and abdomen. These data were employed to develop and test the Bouc–Wen model by inputting the VTS derived chest and abdomen motions into it and using the resulting output signals as surrogates for cardiac motion. The data of the volunteers were divided into training and testing sets. The training set was used to obtain initial values for the model parameters for all of the volunteers in the set, and for set members based on whether they were or were not classified as exhibiting hysteresis using a metric derived from the markers. These initial parameters were then employed with the testing set to estimate output signals. Pearson’s linear correlation coefficient between the

  4. featsel: A framework for benchmarking of feature selection algorithms and cost functions

    OpenAIRE

    Marcelo S. Reis; Gustavo Estrela; Carlos Eduardo Ferreira; Junior Barrera

    2017-01-01

    In this paper, we introduce featsel, a framework for benchmarking of feature selection algorithms and cost functions. This framework allows the user to deal with the search space as a Boolean lattice and has its core coded in C++ for computational efficiency purposes. Moreover, featsel includes Perl scripts to add new algorithms and/or cost functions, generate random instances, plot graphs and organize results into tables. Besides, this framework already comes with dozens of algorithms and co...

  5. Makam Sayyid Husein Bin Abu Bakar Al-Aydarus: Jaringan Spiritual Usmani Di Indonesia Akhir Abad Ke-19

    OpenAIRE

    SUPRATMAN, FRIAL RAMADHAN

    2016-01-01

    This article investigates Indonesian history with transnational approach espe- cially in tracing social community of Indonesia in the context of globalization during nineteenth century. In this article, author focuses on holy tomb of ulama or saint (wali), Sayyid Husein bin Abu Bakar al-Aydarus, who died in the late eighteenth century and buried in Batavia. Although he died more than a century a go, his influence through tomb still can be sensed until now. In the nineteenth century, the tomb ...

  6. Fine mapping of genetic variants in BIN1, CLU, CR1 and PICALM for association with cerebrospinal fluid biomarkers for Alzheimer's disease

    NARCIS (Netherlands)

    Kauwe, John S. K.; Cruchaga, Carlos; Karch, Celeste M.; Sadler, Brooke; Lee, Mo; Mayo, Kevin; Latu, Wayne; Su'a, Manti; Fagan, Anne M.; Holtzman, David M.; Morris, John C.; Goate, Alison M.; Saradha, A.; Abdi, Hervé; Abeliovich, Asa; Abellan van Kan, Gabor; Abner, Erin; Acharya, Deepa; Adams, Nicholas; Adler, Daniel; Agrusti, Antonella; Agyemang, Alex; Ahdidan, Jamila; Ahn, Jae Eun; Aisen, Paul; Aksu, Yaman; Al-Akhras, Mousa; Alarcon, Marcelo; Alberca, Roman; Alexander, Gene; Alexander, Daniel; Almeida, Fabio; Amlien, Inge; Anand, Shyam; Andrew, Marilee; Angersbach, Steve; Anjum, Ayesha; Aoyama, Eiji; Arfanakis, Konstantinos; Armor, Tom; Arnold, Steven; Asatryan, Albert; Ashe-McNalley, Cody; Ashiga, Hirokazu; Assareh, Arezoo; Le Page, Aurelie; Avants, Brian; Avinash, Gopal; Awasthi, Sukrati; Ayan-Oshodi, Mosun; Babic, Tomislav; Baek, Young; Bagci, Ulas; Bai, Shuyang; Baird, Geoffrey; Baker, John; Banks, Sarah; Bard, Jonathan; Barnes, Josephine; Barret, Olivier; Bartlett, Jonathan; Bartzokis, George; Barua, Neil; Bauer, Corinna; Becker, James; Becker, J. Alex; Beckett, Laurel; Bednar, Martin; Beg, Mirza Faisal; Bek, Stephan; Belmokhtar, Nabil; Bernard, Charlotte; Bertram, Lars; Bhaskar, Uday; Biffi, Alessandro; Bigler, Erin; Bilgic, Basar; Bishop, Courtney; Bittner, Daniel; Black, Ronald; Blennow, Kaj; Bogorodzki, Piotr; Bokde, Arun; Bonner-Jackson, Aaron; Boppana, Madhu; Bourgeat, Pierrick; Bowes, Mike; Bowman, Gene; Braskie, Meredith; Braunewell, Karl; Breitner, Joihn; Brewer, James; Brickman, Adam; Britschgi, Markus; Broadbent, Steve; Brogren, Jacob; Brooks, David; Browndyke, Jeffrey; Brunton, Simon; Buchert, Ralph; Buchsbaum, Monte; Buckley, Chris; Buerger, Katharina; Burger, Cyrill; Burnham, Samantha; Burns, Jeffrey; Burton, David; Butman, John; Cabeza, Rafael; Cairns, Nigel; Callhoff, Johanna; Calvini, Piero; Cantillon, Marc; Capella, Heraldo; Cardona-Sanclemente, Luis Eduardo; Carle, Adam; Carmasin, Jeremy; Carranza-Ath, Fredy; Casabianca, Jodi; Casanova, Ramon; Cash, David; Cedarbaum, Jesse; Cella, Massimo; Celsis, Pierre; Chaney, Megan; Chanu, Pascal; Chao, Linda; Charil, Arnaud; Chemali, Zeina; Chen, Kewei; Chen, Minhua; Chen, Rong; Chen, Baojiang; Chen, Jake; Chen, Gennan; Chen, Wei; Cheng, Wei-Chen; Chertkow, Howard; Cheung, Charlton; Cheung, Vinci; Chiang, Gloria; Chiba, Koji; Chin, Simon; Chisholm, Jane; Cho, Youngsang; Choe, John; Choubey, Suresh; Christensen, Anette Luther; Clark, Chris; Clark, David; Clarkson, Matt; Clayton, David; Clunie, David; Coimbra, Alexandre; Compton, David; Coppola, Giovanni; Cover, Keith S.; Crane, Paul; Crans, Gerald; Croop, Robert; Crowther, Daniel; Crum, William; Cui, Yue; Curry, Charles; Curtis, Steven; Cutter, Gary; Daiello, Lori; Dake, Michael; Dale, Anders; Daliri, Mohammad Reza; Damato, Vito Domenico; Darby, Eveleen; Darkner, Sune; Davatzikos, Christos; Dave, Jay; David, Renaud; Davidson, Julie; de Bruijne, Marleen; de Meyer, Geert; de Nunzio, Giorgio; Decarli, Charles; Dechairo, Bryan; DeDuck, Kristina; Dehghan, Hossein; Dejkam, Arsalan; Delfino, Manuel; Dellavedova, Luca; Delpassand, Ebrahim; Delrieu, Julien; Deniz, Oscar; Denney, Douglas; DeOrchis, Vincent; Dépy Carron, Delphine; deToledo-Morrell, Leyla; Devanand, Davangere; Devanarayan, Viswanath; Diaz-Arrastia, Ramon; Dickerson, Bradford; Ding, Xiaobo; Dinov, Ivo; Dobson, Howard; Dodge, Hiroko; Donohue, Michael; Dore, Vincent; Dorflinger, Ernest; Dowling, Maritza; Duan, Xujun; Dubal, Dena; Duchesne, Simon; Duff, Kevin; Dukart, Jürgen; Durazzo, Timothy; Dykstra, Kevin; Earl, Nancy; Edula, Goutham; Ekin, Ahmet; Elcoroaristizabal, Xabier; Emahazion, Tesfai; Engelman, Corinne; Epstein, Noam; Erten-Lyons, Deniz; Eskildsen, Simon; Falcone, Guido; Fan, Yong; Fan, Lingzhong; Farb, Norman; Farnum, Michael; Farrer, Lindsay; Farzan, Ali; Faux, Noel; Feldman, Howard; Feldman, Susan; Fennema-Notestine, Christine; Fernandes, Michel; Fernandez, Elsa; Ferrarini, Luca; Ferreira, Manuel Joao; Ferrer, Eugene; Figurski, Michal; Filipovych, Roman; Fillit, Howard; Finch, Stephen; Finlay, Daniel; Fiot, Jean-Baptiste; Flenniken, Derek; Fletcher, P. Thomas; Fletcher, Evan; Flynn Longmire, Crystal; Focke, Niels; Forman, Mark; Forsythe, Alan; Fox, Steven; Fox-Bosetti, Sabrina; Francis, Alexander L.; Franco-Villalobos, Conrado; Franko, Edit; Freeman, Stefanie; Friedrich, Christoph M.; Friesenhahn, Michel; Frings, Lars; Frisoni, Giovanni; Fritzsche, Klaus; Fujimoto, Yoko; Fujiwara, Ken; Fullerton, Terence; Furney, Simon; Gallins, Paul; Gamst, Anthony; Gan, Ke; Garcia, Maria Teresa; Garg, Gaurav; Gaser, Christian; Gastineau, Edward; Gauthier, Serge; Gavett, Brandon; Gavidia, Giovana; Gazdzinski, Stefan; Ge, Qi; Gemme, Gianluca; Geraci, Joseph; German, Dwight; Ghassabi, Zeinab; Gieschke, Ronald; Gil, Juan E.; Gill, Ryan; Gitelman, Darren; Gleason, Carey; Godbey, Michael; Goghari, Vina; Gold, Michael; Goldberg, Terry; Gomeni, Roberto; Gong, Shangwenyan; Gonzales, Celedon; Goodro, Robert; Gordon, Brian; Gorriz, Juan Manuel; Grachev, Igor; Grandey, Emily; Grasela, Thaddeus; Gratt, Jeremy; Gray, Katherine; Greenberg, Barry; Gregg, Keith; Gregory, Erik; Greicius, Michael; Greve, Douglas; Grill, Joshua; Gross, Alden; Gross, Alan; Guignot, Isabelle; Guo, Qimiao; Guo, Hongbin; Guo, Lianghao; Guo, Jeffrey; Habeck, Christian; Hai, Yizhen; Haight, Thaddeus; Hammarstrom, Per; Hampel, Harald; Han, Jian; Han, Tony; Hanif, Muhammad; Hanna, Yousef; Hardy, Peter; Harvey, Danielle; Hasan, Md Kamrul; Hayashi, Toshihiro; Hazart, Aurelien; He, Huiguang; He, Yong; Head, Denise; Heckemann, Rolf; Heidebrink, Judith; Henderson, David; Henrard, Sébastien; Herholz, Karl; Hernandez, Monica; Herskovits, A. Zara; Hess, Christopher; Hildenbrand, Maike; Hobart, Jeremy; Hoffman, John; Holder, Daniel; Honigberg, Lee; Hoppin, Jack; Horsfield, Mark; Hou, Yangyang; Hsu, Ailing; Hsu, Wei-Wen; Hu, Zhiwei; Hu, Xiaolan; Hu, Zhenghui; Hu, William; Huang, Chien-Chih; Huang, Chingwen; Huang, Shuai; Huang, Yifan; Huang, Juebin; Huang, Chun-Jung; Huang, Shu-Pang; Huang, Fude; Hubbard, Rebecca; Huentelman, Matthew; Hui, Shen; Huppertz, Hans-Jürgen; Hurko, Orest; Hurt, Stephen; Huyck, Susan; Hwang, Scott; Hyun, JungMoon; Ifeachor, Emmanuel; Iglesias, Martina; Ikari, Yasuhiko; Ikonomidou, Vasiliki; Immermann, Fred; Inoue, Lurdes; Insel, Philip; Irizarry, Michael; Irungu, Benson mwangi; Ishibashi, Taro; Ishii, Kenji; Ismail, Sara; Ismail, Shahina; Ito, Kaori; Iturria-Medina, Yasser; Iwatsubo, Takeshi; Iyer, Madhumitha; Jacobson, Mark; Jafari, Aria; Jafari-Khouzani, Kourosh; Jaffe, Carl; Jagust, William; Jara, Hernan; Jasperse, Bas; Jedynak, Bruno; Jefferson, Angela; Jennings, J. Richard; Jessen, Walter; Jia, Fucang; Jiang, Tianzi; Jing, Huang; Johnson, David K.; Jones, Richard; Juengling, Freimut; Juh, Rahyeong; Julin, Per; Uday Bhaskar, K.; Kadish, Bill; Kahle-Wrobleski, Kristin; Kallam, Hanimi Reddy; Kamboh, M. Ilyas; Kaneko, Tomoki; Kaneta, Tomohiro; Karageorgiou, Elissaios; Karantzoulis, Stella; Karlawish, Jason; Katz, Elyse; Kaushik, Sandeep S.; Kauwe, John; Kawakami, Hirofumi; Kazimipoor, Borhan; Kelleher, Thomas; Kennedy, Richard; Kerr, Douglas; Kerrouche, Nacer; Khalil, Iya; Khalil, Andre; Killeen, Neil; Killiany, Ron; Kim, Ana; Kim, Yeonhee; Kim, Heeyoung; Kim, Jong Hun; Kim, Hyoungkyu; Kim, Seongkyun; Kim, Hyewon; Kimberg, Daniel; Kimura, Tokunori; King, Richard; Kirby, Justin; Kirsch, Wolff; Klimas, Michael; Kline, Richard; Kling, Mitchel; Klopfenstein, Erin; Kobayashi, Dione; Koikkalainen, Juha; Kokomoor, Anders; Kolasny, Anthony; Koppel, Jeremy; Korolev, Igor; Kotran, Nickolas; Kouassi, Alex; Kowalczyk, Adam; Kozma, Lynn; Kratzer, Martina; Kuceyeski, Amy; Kuhn, Félix Pierre; Kulkarni, Mauktik; Kumar, Sreedhar; Kuo, Hsun Ting; Kuo, Julie; Kurosawa, Ken; Kwon, Oh Hun; Laforet, Genevieve; Lai, Song; Lakatos, Anita; Lam, On Ki; Lampron, Antoine; Landau, Susan; Landen, Jaren; Lane, Richard; Langbaum, Jessica; Langford, Dianne; Lanius, Vivian; Lavault, Romain; Laxamana, Joel; Le, Trung; Leahy, Richard; Lee, Noah; Lee, Dongsoo; Lee, Vita; Lee, Joseph H.; Lee, Jong-Min; Lefkimmiatis, Stamatis; Lemaitre, Herve; Lenz, Robert; Lester, Gayle; Levey, Allan; Li, Wenjun; Li, Shanshan; Li, Xiaodong; Li, Gang; Li, Ming; Li, Chin-Shang; Li, Lexin; Li, Jinhe; Li, Quanzheng; Li, Yi; Li, Rui; Li, Shi-jiang; Liang, Peipeng; Liang, Lichen; Liang, Kuchang; Liao, Yuan-Lin; Lin, Ling-chih; Lin, Mingkuan; Lin, Ai-Ling; Lin, Lan; Liu, Tianming; Liu, Meijie; Liu, Tao; Liu, Li; Liu, Xiuwen; Liu, Sophia; Liu, Dazhong; Liu, Songling; Liu, Yuan; Liu, Pu; Lo, Raymond; Lobanov, Victor; Loewenstein, David; Logovinsky, Veronika; Long, Xiaojing; Long, Ziyi; Looi, Jeffrey; Lu, Po-Haong; Lukic, Ana; Lull, Juan J.; Luo, Xiongjian; Lynch, John; Ma, Lei; Mackin, Scott; Magda, Sebastian; Maglio, Silvio; Mak, Henry Ka-Fung; Malave, Vicente; Maldjian, Joseph; Mandal, Pravat; Mangin, Jean-Francois; Manjon, Jose; Manohar, Deepak; Mansouri, Chemseddine; Mantri, Ninad; Manzour, Amir; Marambaud, Philippe; Marchewka, Artur; Marek, Kenneth; Markind, Samuel; Marshall, Gad; Martinez Torteya, Antonio; Mather, Mara; Mathis, Chester; Matoug, Sofia; Matsuo, Yoshiyuki; Matthews, Dawn; McArdle, John; McEvoy, Linda; McGeown, William; McIntyre, John; McQuail, Joseph; Meadowcroft, Mark; Meda, Shashwath; Mehta, Nirav; Mendonca, Brian; Menendez, Manuel; Meredith, Jere; Merrill, David; Mesulam, Marek-Marsel; Metti, Andrea; Meyer, Carsten; Mez, Jesse; Mickael, Guedj; Miftahof, Roustem; Mikhno, Arthur; Miller, David; Millikin, Colleen; Min, Ye; Mirza, Mubeena; Mitsis, Effie; Mohan, Ananth; Montana, Giovanni; Moore, Dana; Moradi Birgani, Parmida; Moratal, David; Morimoto, Bruce; Mortamet, Bénédicte; Moscato, Pablo; Motyl, Rafal; Mueller, Kathyrne; Mueller, Susanne; Mueller, Notger; Mukherjee, Shubhabrata; Mulder, Emma; Murayama, Shigeo; Murphy, Michael; Murray, Brian; Musiek, Erik; Myers, Amanda; Najafi, Shahla; Nazarparvar, Babak; Nazeri, Arash; Nettiksimmons, Jasmine; Neu, Scott; Neves, Simone; Ng, Yen-Bee; Nguyen, Nghi; Nguyen Xuan, Tuong; Nicodemus, Kristin; Niecko, Timothy; Nielsen, Casper; Notomi, Keiji; Nuneez Benjumea, Francisco; O'Bryant, Sid; O'Neil, Alison; Obisesan, Thomas; Oh, Dong Hoon; Oh, Joonmi; Okonkwo, Ozioma; Olde Rikkert, Marcel; Olmos, Salvador; Ortner, Marion; Ostrowitzki, Susanne; Oswald, Annahita; Ott, Brian; Ourselin, Sebastien; Ouyang, Gaoxiang; Paiva, Renata; Pan, Zhifang; Pande, Yogesh; Pardo, Jose; Pardoe, Heath; Park, Hyunjin; Park, Moon Ho; Park, Sang hyun; Park, Kee Hyung; Park, Sujin; Parsey, Ramin; Parveen, Riswana; Paskavitz, James; Patel, Yogen; Patil, Manasi; Pawlak, Mikolaj; Payoux, Pierre; Pearson, Jim; Peavy, Guerry; Pell, Gaby; Peng, Yahong; Pennec, Xavier; Pepin, Jean louis; Perea, Rodrigo; Perneczky, Robert; Petitti, Diana; Petrella, Jeffrey; Peyrat, Jean-Marc; Pezoa, Jorge; Pham, Chi-Tuan; Phillips, Nicole; Pierson, Ronald; Piovezan, Mauro; Podhorski, Adam; Pollari, Mika; Pontecorvo, Michael; Poppenk, Jordan; Posner, Holly; Potkin, Steven; Potter, Elizabeth; Poulin, Stephane; Prasad, Gautam; Prenger, Kurt; Prince, Jerry; Priya, Anandh; Puchakayala, Shashidhar Reddy; Qiu, Anqi; Qiu, Ruolun; Qiu, Wendy; Qualls, Constance Dean; Rabie, Huwaida; Rajeesh, Rajeesh; Rallabandi, V. P. Subramanyam; Ramage, Amy; Randolph, Christopher; Rao, Anil; Rao, Divya; Raubertas, Richard; Ray, Debashis; Razak, Hana; Redolfi, Alberto; Reed, Bruce; Reid, Andrew; Reilhac, Anthonin; Reinsberger, Claus; Restrepo, Lucas; Retico, Alessandra; Rezaeitabar, Yousef; Richards, John; Richter, Mirco; Riddle, William; Ries, Michele; Rincón, Mariano; Rischall, Matt; Robieson, Weining; Rocha-Rego, Vanessa; Rogalski, Emily; Rogers, Elizabeth; Rojas, Ignacio; Rojas Balderrama, Javier; Romero, Klaus; Rorden, Chris; Rosand, Jonathan; Rosen, Allyson; Rosen, Ori; Rosenberg, Paul; Ross, David; Ross, Joel; Roubini, Eli; Rousseau, François; Rowe, Christopher; Rubin, Daniel; Rubright, Jonathan; Ruiz, Agustin; Rusinek, Henry; Ryan, Laurie; Saad, Ahmed; Sabbagh, Marway; Sabuncu, Mert; Sachs, Michael; Sacuiu, Simona; Sadeghi, Ali; Said, Yasmine; Saint-Aubert, Laure; Sakata, Muneyuki; Salat, David; Salmon, David; Salomi, Sharmila; Salter, Hugh; Samwald, Matthias; Sanchez, Luciano; Sanders, Elizabeth; Sanjo, Nobuo; Sarnel, Haldun; Sato, Shinji; Sato, Hajime; Saumier, Daniel; Savio, Alexandre; Sawada, Ikuhisa; Saykin, Andrew; Schaffer, J. David; Scharre, Douglas; Schegerin, Marc; Schlosser, Gretchen; Schmand, Ben; Schmansky, Nick; Schmidt, Mark; Schneider, Lon; Schramm, Hauke; Schuerch, Markus; Schwartz, Craig; Schwartz, Eben; Schwarz, Adam; Seethamraju, Ravi; Seixas, Flavio; Selnes, Per; Senjem, Matthew; Senlin, Wang; Seo, Sang Won; Sethuraman, Gopalan; Sevigny, Jeffrey; Sfikas, Giorgos; Sghedoni, Roberto; Shah, Said Khalid; Shahbaba, Babak; Shams, Soheil; Shattuck, David; Shaw, Leslie; Sheela, Jaba; Shen, Weijia; Shen, Qian; Shera, David; Sherman, John; Sherva, Richard; Shi, Feng; Shukla, Vinay; Shuler, Catherine; Shulman, Joshua; Siegel, Rene; Siemers, Eric; Silveira, Margarida; Silver, Michael; Silverman, Daniel; Sim, Ida; Simmons, Andy; Simoes, Rita; Simon, Melvin; Simpson, Ivor; Singh, Simer Preet; Singh, Nikhil; Siuciak, Judy; Sjögren, Niclas; Skup, Martha; Small, Gary; Smith, Michael; Smith, Charles; Smith, Benjamin; Smyth, Timothy; Snow, Sarah; Soares, Holly; Soldea, Octavian; Solomon, Alan; Solomon, Paul; Som, Subhojit; Song, Changhong; Song, Mingli; Sorensen, Greg; Soudah, Eduardo; Spampinato, Maria Vittoria; Spenger, Christian; Sperling, Reisa; Spiegel, René; Spies, Lothar; Squarcia, Sandro; Squire, Larry; Staff, Roger; Stern, Yaakov; Straw, Jack; Strittmatter, Stephen; Stühler, Elisabeth; Styren, Scot; Subramanian, Vijayalakshmi; Sugishita, Morihiro; Sukkar, Rafid; Sun, Ying; Sun, Yu; Sun, Jia; Sundell, Karen; Suri, Muhammad; Suzuki, Akiyuki; Svetnik, Vladimir; Swan, Melanie; Takahasi, Tetsuhiko; Takeuchi, Tomoko; Tanaka, Shoji; Tancredi, Daniel; Tang, Songyuan; Tao, Dacheng; Tao, Wenwen; Tariot, Pierre; Taylor-Reinwald, Lisa; Teng, Edmond; Terlizzi, Rita; Thiele, Frank; Thomas, Ronald; Thomas, Benjamin; Thompson, Paul; Thompson, Wesley; Thornton-Wells, Tricia; Thurfjell, Lennart; Titeux, Laurence; Tokuda, Takahiko; Toledo, Juan B.; Tolli, Tuomas; Toma, Ahmed; Tomita, Naoki; Toro, Roberto; Tosun, Duygu; Tousian, Mona; Toussaint, Paule; Toyoshiba, Hiroyoshi; Tractenberg, Rochelle E.; Trittschuh, Emily; Trojanowski, John; Truran, Diana; Tsechpenakis, Gavriil; Tucker-Drob, Elliot; Tufail, Ahsan; Tung, Joyce; Ueda, Yoji; Ullrich, Lauren; Umadevi Venkataraju, Kannan; Umar, Nisser; Uzunbas, Gokhan; van de Nes, Joseph; van der Brug, Marcel; van Horn, John; van Leemput, Koen; van Train, Kenneth; van Zeeland, Ashley; Vasanawala, Minal; Vemuri, Prashanthi; Verwaerde, Philippe; Videbaek, Charlotte; Vidoni, Eric; Vigneron, Vincent; Villanueva-Meyer, Javier; Visser, Pieter Jelle; Vitolo, Ottavio; Vounou, Maria; Wade, Sara; Walhovd, Kristine B.; Wan, Hong; Wang, Lubin; Wang, Xu; Wang, Ze; Wang, Angela; Wang, Tiger; Wang, Yongmei Michelle; Wang, Yaping; Wang, Wei; Wang, Huali; Wang, Yue; Wang, Li-San; Wang, Huanli; Wang, Alex; Wang, Yalin; Wang, Lei; Ward, Michael; Warfield, Simon; Waring, Stephen; Watanabe, Toshiyuki; Webb, David; Wei, Lili; Weiner, Michael; Wen, Shu-Hui; Wenjing, Li; Wenzel, Fabian; Westlye, Lars T.; Whitcher, Brandon; Whitlow, Christopher; Whitwell, Jennifer; Wilhelmsen, Kirk; Williams, David; Wilmot, Beth; Wingo, Thomas; Winkler, Andreas; Wiste, Heather; Wolfson, Tanya; Wolke, Ira; Wolz, Robin; Woo, Jongwook; Woo, Ellen; Woods, Lynn; Worth, Andrew; Worth, Eric; Wouters, Hans; Wu, Teresa; Wu, Ellen; Wu, Yi-Gen; Wu, Liang; Wu, Xiaoling; Wyman, Bradley; Wyss-Coray, Tony; Xiao, Liu; Xiao, Guanghua; Xie, Sharon; Xu, Jun; Xu, Ye; Xu, Yi-Zheng; Xu, Guofan; Yamane, Tomohiko; Yamashita, Fumio; Yan, Yunyi; Yan, Pingkun; Yang, Jinzhong; Yang, Qing X.; Yang, Zijiang; Yang, Guang; Yang, Wenlu; Yang, Eric; Yang, Zhitong; Ye, Jieping; Ye, Jong; Ye, Liang; Ye, Byoung Seok; Yee, Laura; Yesavage, Jerome; Ying, Song; Yoo, Bongin; Young, Jonathan; Yu, Dongchuan; Yu, Shiwei; Yuan, Kai; Yuan, Guihong; Yushkevich, Paul; Zaborszky, Laszlo; Zagorodnov, Vitali; Zagorski, Michael; Zawadzki, Rezi; Zeitzer, Jamie; Zhang, Huixiong; Zhang, Tianhao; Zhang, Ping; Zhang, Xin; Zhang, Bin; Zhang, Jing; Zhang, Linda; Zhang, Lijun; Zhang, Kurt; Zhao, Jim; Zhao, Peng; Zhao, Qinying; Zhen, Xiantong; Zheng, Yuanjie; Zhijun, Yao; Zhou, Sheng; Zhou, Bin; Zhu, Wanlin; Zhu, Hongtu; Zhu, Wen; Zito, Giancarlo; Zou, Heng

    2011-01-01

    Recent genome-wide association studies of Alzheimer's disease (AD) have identified variants in BIN1, CLU, CR1 and PICALM that show replicable association with risk for disease. We have thoroughly sampled common variation in these genes, genotyping 355 variants in over 600 individuals for whom

  7. Self-similar and self-affine pionization in nuclear interactions at a few AgeV

    International Nuclear Information System (INIS)

    Ghosh, Dipak; Deb, Argha; Chattopadhyay, Keya Dutta; Sarkar, Rinku; Dutta, Ishita Sen

    2004-01-01

    Self-affine multiplicity scaling is investigated in the framework of two-dimensional factorial moment methodology using the concept of the Hurst exponent (H) considering different bins of the phase space. We have investigated the fluctuation pattern of emitted pions in 24 Mg-AgBr interactions at 4.5 AGeV and this study reveals that the fluctuation is self-similar in some bins, whereas it is self-affine in other bins, that is, the multiplicity scaling is bin-dependent. (author)

  8. Bioenergy Knowledge Discovery Framework Fact Sheet

    Energy Technology Data Exchange (ETDEWEB)

    None

    2017-07-01

    The Bioenergy Knowledge Discovery Framework (KDF) supports the development of a sustainable bioenergy industry by providing access to a variety of data sets, publications, and collaboration and mapping tools that support bioenergy research, analysis, and decision making. In the KDF, users can search for information, contribute data, and use the tools and map interface to synthesize, analyze, and visualize information in a spatially integrated manner.

  9. Evaluation of Conceptual Frameworks Applicable to the Study of Isolation Precautions Effectiveness

    Science.gov (United States)

    Crawford, Catherine; Shang, Jingjing

    2015-01-01

    Aims A discussion of conceptual frameworks applicable to the study of isolation precautions effectiveness according to Fawcett and DeSanto-Madeya’s (2013) evaluation technique and their relative merits and drawbacks for this purpose Background Isolation precautions are recommended to control infectious diseases with high morbidity and mortality, but effectiveness is not established due to numerous methodological challenges. These challenges, such as identifying empirical indicators and refining operational definitions, could be alleviated though use of an appropriate conceptual framework. Design Discussion paper Data Sources In mid-April 2014, the primary author searched five electronic, scientific literature databases for conceptual frameworks applicable to study isolation precautions, without limiting searches by publication date. Implications for Nursing By reviewing promising conceptual frameworks to support isolation precautions effectiveness research, this paper exemplifies the process to choose an appropriate conceptual framework for empirical research. Hence, researchers may build on these analyses to improve study design of empirical research in multiple disciplines, which may lead to improved research and practice. Conclusion Three frameworks were reviewed: the epidemiologic triad of disease, Donabedian’s healthcare quality framework and the Quality Health Outcomes model. Each has been used in nursing research to evaluate health outcomes and contains concepts relevant to nursing domains. Which framework can be most useful likely depends on whether the study question necessitates testing multiple interventions, concerns pathogen-specific characteristics and yields cross-sectional or longitudinal data. The Quality Health Outcomes model may be slightly preferred as it assumes reciprocal relationships, multi-level analysis and is sensitive to cultural inputs. PMID:26179813

  10. Accelerated time-of-flight (TOF) PET image reconstruction using TOF bin subsetization and TOF weighting matrix pre-computation

    International Nuclear Information System (INIS)

    Mehranian, Abolfazl; Kotasidis, Fotis; Zaidi, Habib

    2016-01-01

    Time-of-flight (TOF) positron emission tomography (PET) technology has recently regained popularity in clinical PET studies for improving image quality and lesion detectability. Using TOF information, the spatial location of annihilation events is confined to a number of image voxels along each line of response, thereby the cross-dependencies of image voxels are reduced, which in turns results in improved signal-to-noise ratio and convergence rate. In this work, we propose a novel approach to further improve the convergence of the expectation maximization (EM)-based TOF PET image reconstruction algorithm through subsetization of emission data over TOF bins as well as azimuthal bins. Given the prevalence of TOF PET, we elaborated the practical and efficient implementation of TOF PET image reconstruction through the pre-computation of TOF weighting coefficients while exploiting the same in-plane and axial symmetries used in pre-computation of geometric system matrix. In the proposed subsetization approach, TOF PET data were partitioned into a number of interleaved TOF subsets, with the aim of reducing the spatial coupling of TOF bins and therefore to improve the convergence of the standard maximum likelihood expectation maximization (MLEM) and ordered subsets EM (OSEM) algorithms. The comparison of on-the-fly and pre-computed TOF projections showed that the pre-computation of the TOF weighting coefficients can considerably reduce the computation time of TOF PET image reconstruction. The convergence rate and bias-variance performance of the proposed TOF subsetization scheme were evaluated using simulated, experimental phantom and clinical studies. Simulations demonstrated that as the number of TOF subsets is increased, the convergence rate of MLEM and OSEM algorithms is improved. It was also found that for the same computation time, the proposed subsetization gives rise to further convergence. The bias-variance analysis of the experimental NEMA phantom and a clinical

  11. Toward a public analysis database for LHC new physics searches using M ADA NALYSIS 5

    Science.gov (United States)

    Dumont, B.; Fuks, B.; Kraml, S.; Bein, S.; Chalons, G.; Conte, E.; Kulkarni, S.; Sengupta, D.; Wymant, C.

    2015-02-01

    We present the implementation, in the MadAnalysis 5 framework, of several ATLAS and CMS searches for supersymmetry in data recorded during the first run of the LHC. We provide extensive details on the validation of our implementations and propose to create a public analysis database within this framework.

  12. Analysis of energy efficiency retrofit schemes for heating, ventilating and air-conditioning systems in existing office buildings based on the modified bin method

    International Nuclear Information System (INIS)

    Wang, Zhaoxia; Ding, Yan; Geng, Geng; Zhu, Neng

    2014-01-01

    Highlights: • A modified bin method is adopted to propose and optimize the EER schemes. • A case study is presented to demonstrate the analysis procedures of EER schemes. • Pertinent EER schemes for HVAC systems are proposed for the object building. - Abstract: Poor thermal performance of building envelop and low efficiencies of heating, ventilating and air-conditioning (HVAC) systems can always be found in the existing office buildings with large energy consumption. This paper adopted a modified bin method to propose and optimize the energy efficiency retrofit (EER) schemes. An existing office building in Tianjin was selected as an example to demonstrate the procedures of formulating the design scheme. Pertinent retrofit schemes for HVAC system were proposed after the retrofit of building envelop. With comprehensive consideration of energy efficiency and economic benefits, the recommended scheme that could improve the overall energy efficiency by 71.20% was determined

  13. Brassinosteriod Insensitive 2 (BIN2) acts as a downstream effector of the Target of Rapamycin (TOR) signaling pathway to regulate photoautotrophic growth in Arabidopsis.

    Science.gov (United States)

    Xiong, Fangjie; Zhang, Rui; Meng, Zhigang; Deng, Kexuan; Que, Yumei; Zhuo, Fengping; Feng, Li; Guo, Sundui; Datla, Raju; Ren, Maozhi

    2017-01-01

    The components of the target of rapamycin (TOR) signaling pathway have been well characterized in heterotrophic organisms from yeast to humans. However, because of rapamycin insensitivity, embryonic lethality in tor null mutants and a lack of reliable ways of detecting TOR protein kinase in higher plants, the key players upstream and downstream of TOR remain largely unknown in plants. Using engineered rapamycin-sensitive Binding Protein 12-2 (BP12-2) plants, the present study showed that combined treatment with rapamycin and active-site TOR inhibitors (asTORis) results in synergistic inhibition of TOR activity and plant growth in Arabidopsis. Based on this system, we revealed that TOR signaling plays a crucial role in modulating the transition from heterotrophic to photoautotrophic growth in Arabidopsis. Ribosomal protein S6 kinase 2 (S6K2) was identified as a direct downstream target of TOR, and the growth of TOR-suppressed plants could be rescued by up-regulating S6K2. Systems, genetic, and biochemical analyses revealed that Brassinosteriod Insensitive 2 (BIN2) acts as a novel downstream effector of S6K2, and the phosphorylation of BIN2 depends on TOR-S6K2 signaling in Arabidopsis. By combining pharmacological with genetic and biochemical approaches, we determined that the TOR-S6K2-BIN2 signaling pathway plays important roles in regulating the photoautotrophic growth of Arabidopsis. © 2016 The Authors. New Phytologist © 2016 New Phytologist Trust.

  14. Search for the Pentaquark via the Decay $P^0_{\\bar{c} s} \\to K^{*} K p$

    Energy Technology Data Exchange (ETDEWEB)

    Hurvits, Gilhad [Tel Aviv U.

    1997-12-01

    The goal of this work was to search for the pentaquark state via the $K^* Kp$ decay channel, within the framework of E791. The thesis covered the theoretical motivation that led to the search, description of the experimental setup, the analysis methods and the results

  15. Theories, models and frameworks used in capacity building interventions relevant to public health: a systematic review.

    Science.gov (United States)

    Bergeron, Kim; Abdi, Samiya; DeCorby, Kara; Mensah, Gloria; Rempel, Benjamin; Manson, Heather

    2017-11-28

    There is limited research on capacity building interventions that include theoretical foundations. The purpose of this systematic review is to identify underlying theories, models and frameworks used to support capacity building interventions relevant to public health practice. The aim is to inform and improve capacity building practices and services offered by public health organizations. Four search strategies were used: 1) electronic database searching; 2) reference lists of included papers; 3) key informant consultation; and 4) grey literature searching. Inclusion and exclusion criteria are outlined with included papers focusing on capacity building, learning plans, professional development plans in combination with tools, resources, processes, procedures, steps, model, framework, guideline, described in a public health or healthcare setting, or non-government, government, or community organizations as they relate to healthcare, and explicitly or implicitly mention a theory, model and/or framework that grounds the type of capacity building approach developed. Quality assessment were performed on all included articles. Data analysis included a process for synthesizing, analyzing and presenting descriptive summaries, categorizing theoretical foundations according to which theory, model and/or framework was used and whether or not the theory, model or framework was implied or explicitly identified. Nineteen articles were included in this review. A total of 28 theories, models and frameworks were identified. Of this number, two theories (Diffusion of Innovations and Transformational Learning), two models (Ecological and Interactive Systems Framework for Dissemination and Implementation) and one framework (Bloom's Taxonomy of Learning) were identified as the most frequently cited. This review identifies specific theories, models and frameworks to support capacity building interventions relevant to public health organizations. It provides public health practitioners

  16. Charter Schools and the Teacher Job Search in Michigan

    Science.gov (United States)

    Cannata, Marisa

    2010-01-01

    This paper examines the position of charter schools in prospective elementary teachers' job search decisions. Using a labor market segmentation framework, it explores teacher applicants' decisions to apply to charter schools. The data come from a mixed-methods longitudinal study of prospective teachers looking for their first job. This paper finds…

  17. Foraging in Semantic Fields: How We Search Through Memory.

    Science.gov (United States)

    Hills, Thomas T; Todd, Peter M; Jones, Michael N

    2015-07-01

    When searching for concepts in memory--as in the verbal fluency task of naming all the animals one can think of--people appear to explore internal mental representations in much the same way that animals forage in physical space: searching locally within patches of information before transitioning globally between patches. However, the definition of the patches being searched in mental space is not well specified. Do we search by activating explicit predefined categories (e.g., pets) and recall items from within that category (categorical search), or do we activate and recall a connected sequence of individual items without using categorical information, with each item recalled leading to the retrieval of an associated item in a stream (associative search), or both? Using semantic representations in a search of associative memory framework and data from the animal fluency task, we tested competing hypotheses based on associative and categorical search models. Associative, but not categorical, patch transitions took longer to make than position-matched productions, suggesting that categorical transitions were not true transitions. There was also clear evidence of associative search even within categorical patch boundaries. Furthermore, most individuals' behavior was best explained by an associative search model without the addition of categorical information. Thus, our results support a search process that does not use categorical information, but for which patch boundaries shift with each recall and local search is well described by a random walk in semantic space, with switches to new regions of the semantic space when the current region is depleted. Copyright © 2015 Cognitive Science Society, Inc.

  18. Intelligent Robot-assisted Humanitarian Search and Rescue System

    Directory of Open Access Journals (Sweden)

    Henry Y. K. Lau

    2009-11-01

    Full Text Available The unprecedented scale and number of natural and man-made disasters in the past decade has urged international emergency search and rescue communities to seek for novel technology to enhance operation efficiency. Tele-operated search and rescue robots that can navigate deep into rubble to search for victims and to transfer critical field data back to the control console has gained much interest among emergency response institutions. In response to this need, a low-cost autonomous mini robot equipped with thermal sensor, accelerometer, sonar, pin-hole camera, microphone, ultra-bright LED and wireless communication module is developed to study the control of a group of decentralized mini search and rescue robots. The robot can navigate autonomously between voids to look for living body heat and can send back audio and video information to allow the operator to determine if the found object is a living human. This paper introduces the design and control of a low-cost robotic search and rescue system based on an immuno control framework developed for controlling decentralized systems. Design and development of the physical prototype and the immunity-based control system are described in this paper.

  19. Intelligent Robot-Assisted Humanitarian Search and Rescue System

    Directory of Open Access Journals (Sweden)

    Albert W. Y. Ko

    2009-06-01

    Full Text Available The unprecedented scale and number of natural and man-made disasters in the past decade has urged international emergency search and rescue communities to seek for novel technology to enhance operation efficiency. Tele-operated search and rescue robots that can navigate deep into rubble to search for victims and to transfer critical field data back to the control console has gained much interest among emergency response institutions. In response to this need, a low-cost autonomous mini robot equipped with thermal sensor, accelerometer, sonar, pin-hole camera, microphone, ultra-bright LED and wireless communication module is developed to study the control of a group of decentralized mini search and rescue robots. The robot can navigate autonomously between voids to look for living body heat and can send back audio and video information to allow the operator to determine if the found object is a living human. This paper introduces the design and control of a low-cost robotic search and rescue system based on an immuno control framework developed for controlling decentralized systems. Design and development of the physical prototype and the immunity-based control system are described in this paper.

  20. Social Media Contribution to the Promotion of Digital Citizenship among Female Students at Imam Mohammed bin Saud Islamic University in Riyadh

    Science.gov (United States)

    Alharbi, Wafa Owaydhah; Alturki, Khaled Ibrahim

    2018-01-01

    The study aimed to identify the degree of social media contribution to reinforcing digital citizenship meaning from the viewpoint of female students at Imam Mohammed bin Saud Islamic University in Riyadh. The study was an attempt to answer the following two questions in order to achieve the objectives of the study: To which extent does SnapChat…

  1. Search for Radions at LEP2

    CERN Document Server

    Abbiendi, G.; Akesson, P.F.; Alexander, G.; Allison, John; Amaral, P.; Anagnostou, G.; Anderson, K.J.; Asai, S.; Axen, D.; Bailey, I.; Barberio, E.; Barillari, T.; Barlow, R.J.; Batley, R.J.; Bechtle, P.; Behnke, T.; Bell, Kenneth Watson; Bell, P.J.; Bella, G.; Bellerive, A.; Benelli, G.; Bethke, S.; Biebel, O.; Boeriu, O.; Bock, P.; Boutemeur, M.; Braibant, S.; Brown, Robert M.; Burckhart, H.J.; Campana, S.; Capiluppi, P.; Carnegie, R.K.; Carter, A.A.; Carter, J.R.; Chang, C.Y.; Charlton, D.G.; Ciocca, C.; Csilling, A.; Cuffiani, M.; Dado, S.; De Roeck, A.; De Wolf, E.A.; Desch, K.; Dienes, B.; Donkers, M.; Dubbert, J.; Duchovni, E.; Duckeck, G.; Duerdoth, I.P.; Etzion, E.; Fabbri, F.; Ferrari, P.; Fiedler, F.; Fleck, I.; Ford, M.; Frey, A.; Gagnon, P.; Gary, John William; Geich-Gimbel, C.; Giacomelli, G.; Giacomelli, P.; Giunta, Marina; Goldberg, J.; Gross, E.; Grunhaus, J.; Gruwe, M.; Gunther, P.O.; Gupta, A.; Hajdu, C.; Hamann, M.; Hanson, G.G.; Harel, A.; Hauschild, M.; Hawkes, C.M.; Hawkings, R.; Hemingway, R.J.; Herten, G.; Heuer, R.D.; Hill, J.C.; Hoffman, Kara Dion; Horvath, D.; Igo-Kemenes, P.; Ishii, K.; Jeremie, H.; Jovanovic, P.; Junk, T.R.; Kanzaki, J.; Karlen, D.; Kawagoe, K.; Kawamoto, T.; Keeler, R.K.; Kellogg, R.G.; Kennedy, B.W.; Kluth, S.; Kobayashi, T.; Kobel, M.; Komamiya, S.; Kramer, T.; Krieger, P.; von Krogh, J.; Kuhl, T.; Kupper, M.; Lafferty, G.D.; Landsman, H.; Lanske, D.; Lellouch, D.; Lettso, J.; Levinson, L.; Lillich, J.; Lloyd, S.L.; Loebinger, F.K.; Lu, J.; Ludwig, A.; Ludwig, J.; Mader, W.; Marcellini, S.; Martin, A.J.; Masetti, G.; Mashimo, T.; Mattig, Peter; McKenna, J.; McPherson, R.A.; Meijers, F.; Menges, W.; Merritt, F.S.; Mes, H.; Meyer, Niels T.; Michelini, A.; Mihara, S.; Mikenberg, G.; Miller, D.J.; Mohr, W.; Mori, T.; Mutter, A.; Nagai, K.; Nakamura, I.; Nanjo, H.; Neal, H.A.; Nisius, R.; O'Neale, S.W.; Oh, A.; Oreglia, M.J.; Orito, S.; Pahl, C.; Pasztor, G.; Pater, J.R.; Pilcher, J.E.; Pinfold, J.; Plane, David E.; Pooth, O.; Przybycien, M.; Quadt, A.; Rabbertz, K.; Rembser, C.; Renkel, P.; Roney, J.M.; Rossi, A.M.; Rozen, Y.; Runge, K.; Sachs, K.; Saeki, T.; Sarkisyan, E.K.G.; Schaile, A.D.; Schaile, O.; Scharff-Hansen, P.; Schieck, J.; Schorner-Sadenius, T.; Schroder, Matthias; Schumacher, M.; Seuster, R.; Shears, T.G.; Shen, B.C.; Sherwood, P.; Skuja, A.; Smith, A.M.; Sobie, R.; Soldner-Rembold, S.; Spano, F.; Stahl, A.; Strom, David M.; Strohmer, R.; Tarem, S.; Tasevsky, M.; Teuscher, R.; Thomson, M.A.; Torrence, E.; Toya, D.; Tran, P.; Trigger, I.; Trocsanyi, Z.; Tsur, E.; Turner-Watson, M.F.; Ueda, I.; Ujvari, B.; Vollmer, C.F.; Vannerem, P.; Vertesi, R.; Verzocchi, M.; Voss, H.; Vossebeld, J.; Ward, C.P.; Ward, D.R.; Watkins, P.M.; Watson, A.T.; Watson, N.K.; Wells, P.S.; Wengler, T.; Wermes, N.; Wilson, G.W.; Wilson, J.A.; Wolf, G.; Wyatt, T.R.; Yamashita, S.; Zer-Zion, D.; Zivkovic, Lidija

    2005-01-01

    A new scalar resonance, called the radion, with couplings to fermions and bosons similar to those of the Higgs boson, is predicted in the framework of Randall-Sundrum models, proposed solutions to the hierarchy problem with one extra dimension. An important distinction between the radion and the Higgs boson is that the radion would couple directly to gluon pairs, and in particular its decay products would include a significant fraction of gluon jets. The radion had the same quantum numbers as the Standard Model (SM) Higgs boson, and therefore they can mix, with the resulting mass eigenstates having properties different from those of the SM Higgs boson. Existing searches for the Higgs boson are sensitive to the possible production and decay of radions and Higgs bosons in these models. For the first time, searches for the SM Higgs boson and flavour-independent and decay-mode independent searches for a neutral Higgs boson are used in combination to explore the parameter space of the Randall-Sundrum model. In the...

  2. Simplified Models for LHC New Physics Searches

    CERN Document Server

    Alves, Daniele; Arora, Sanjay; Bai, Yang; Baumgart, Matthew; Berger, Joshua; Buckley, Matthew; Butler, Bart; Chang, Spencer; Cheng, Hsin-Chia; Cheung, Clifford; Chivukula, R.Sekhar; Cho, Won Sang; Cotta, Randy; D'Alfonso, Mariarosaria; El Hedri, Sonia; Essig, Rouven; Evans, Jared A.; Fitzpatrick, Liam; Fox, Patrick; Franceschini, Roberto; Freitas, Ayres; Gainer, James S.; Gershtein, Yuri; Gray, Richard; Gregoire, Thomas; Gripaios, Ben; Gunion, Jack; Han, Tao; Haas, Andy; Hansson, Per; Hewett, JoAnne; Hits, Dmitry; Hubisz, Jay; Izaguirre, Eder; Kaplan, Jared; Katz, Emanuel; Kilic, Can; Kim, Hyung-Do; Kitano, Ryuichiro; Koay, Sue Ann; Ko, Pyungwon; Krohn, David; Kuflik, Eric; Lewis, Ian; Lisanti, Mariangela; Liu, Tao; Liu, Zhen; Lu, Ran; Luty, Markus; Meade, Patrick; Morrissey, David; Mrenna, Stephen; Nojiri, Mihoko; Okui, Takemichi; Padhi, Sanjay; Papucci, Michele; Park, Michael; Park, Myeonghun; Perelstein, Maxim; Peskin, Michael; Phalen, Daniel; Rehermann, Keith; Rentala, Vikram; Roy, Tuhin; Ruderman, Joshua T.; Sanz, Veronica; Schmaltz, Martin; Schnetzer, Stephen; Schuster, Philip; Schwaller, Pedro; Schwartz, Matthew D.; Schwartzman, Ariel; Shao, Jing; Shelton, Jessie; Shih, David; Shu, Jing; Silverstein, Daniel; Simmons, Elizabeth; Somalwar, Sunil; Spannowsky, Michael; Spethmann, Christian; Strassler, Matthew; Su, Shufang; Tait, Tim; Thomas, Brooks; Thomas, Scott; Toro, Natalia; Volansky, Tomer; Wacker, Jay; Waltenberger, Wolfgang; Yavin, Itay; Yu, Felix; Zhao, Yue; Zurek, Kathryn

    2012-01-01

    This document proposes a collection of simplified models relevant to the design of new-physics searches at the LHC and the characterization of their results. Both ATLAS and CMS have already presented some results in terms of simplified models, and we encourage them to continue and expand this effort, which supplements both signature-based results and benchmark model interpretations. A simplified model is defined by an effective Lagrangian describing the interactions of a small number of new particles. Simplified models can equally well be described by a small number of masses and cross-sections. These parameters are directly related to collider physics observables, making simplified models a particularly effective framework for evaluating searches and a useful starting point for characterizing positive signals of new physics. This document serves as an official summary of the results from the "Topologies for Early LHC Searches" workshop, held at SLAC in September of 2010, the purpose of which was to develop a...

  3. Intelligent search in Big Data

    Science.gov (United States)

    Birialtsev, E.; Bukharaev, N.; Gusenkov, A.

    2017-10-01

    An approach to data integration, aimed on the ontology-based intelligent search in Big Data, is considered in the case when information objects are represented in the form of relational databases (RDB), structurally marked by their schemes. The source of information for constructing an ontology and, later on, the organization of the search are texts in natural language, treated as semi-structured data. For the RDBs, these are comments on the names of tables and their attributes. Formal definition of RDBs integration model in terms of ontologies is given. Within framework of the model universal RDB representation ontology, oil production subject domain ontology and linguistic thesaurus of subject domain language are built. Technique of automatic SQL queries generation for subject domain specialists is proposed. On the base of it, information system for TATNEFT oil-producing company RDBs was implemented. Exploitation of the system showed good relevance with majority of queries.

  4. Optimal search filters for renal information in EMBASE.

    Science.gov (United States)

    Iansavichus, Arthur V; Haynes, R Brian; Shariff, Salimah Z; Weir, Matthew; Wilczynski, Nancy L; McKibbon, Ann; Rehman, Faisal; Garg, Amit X

    2010-07-01

    EMBASE is a popular database used to retrieve biomedical information. Our objective was to develop and test search filters to help clinicians and researchers efficiently retrieve articles with renal information in EMBASE. We used a diagnostic test assessment framework because filters operate similarly to screening tests. We divided a sample of 5,302 articles from 39 journals into development and validation sets of articles. Information retrieval properties were assessed by treating each search filter as a "diagnostic test" or screening procedure for the detection of relevant articles. We tested the performance of 1,936,799 search filters made of unique renal terms and their combinations. REFERENCE STANDARD & OUTCOME: The reference standard was manual review of each article. We calculated the sensitivity and specificity of each filter to identify articles with renal information. The best renal filters consisted of multiple search terms, such as "renal replacement therapy," "renal," "kidney disease," and "proteinuria," and the truncated terms "kidney," "dialy," "neph," "glomerul," and "hemodial." These filters achieved peak sensitivities of 98.7% (95% CI, 97.9-99.6) and specificities of 98.5% (95% CI, 98.0-99.0). The retrieval performance of these filters remained excellent in the validation set of independent articles. The retrieval performance of any search will vary depending on the quality of all search concepts used, not just renal terms. We empirically developed and validated high-performance renal search filters for EMBASE. These filters can be programmed into the search engine or used on their own to improve the efficiency of searching.

  5. Search for supersymmetry in final states with missing transverse energy and 0, 1, 2, or ≥3 b-quark jets in 7 TeV pp collisions using the variable α T

    Energy Technology Data Exchange (ETDEWEB)

    Chatrchyan, S.; Khachatryan, V.; Sirunyan, A. M.; Tumasyan, A.; Adam, W.; Aguilo, E.; Bergauer, T.; Dragicevic, M.; Erö, J.; Fabjan, C.; Friedl, M.; Frühwirth, R.; Ghete, V. M.; Hammer, J.; Hörmann, N.; Hrubec, J.; Jeitler, M.; Kiesenhofer, W.; Knünz, V.; Krammer, M.; Krätschmer, I.; Liko, D.; Mikulec, I.; Pernicka, M.; Rahbaran, B.; Rohringer, C.; Rohringer, H.; Schöfbeck, R.; Strauss, J.; Taurok, A.; Waltenberger, W.; Walzel, G.; Widl, E.; Wulz, C. -E.; Mossolov, V.; Shumeiko, N.; Suarez Gonzalez, J.; Bansal, M.; Bansal, S.; Cornelis, T.; De Wolf, E. A.; Janssen, X.; Luyckx, S.; Mucibello, L.; Ochesanu, S.; Roland, B.; Rougny, R.; Selvaggi, M.; Staykova, Z.; Van Haevermaet, H.; Van Mechelen, P.; Van Remortel, N.; Van Spilbeeck, A.; Blekman, F.; Blyweert, S.; D’Hondt, J.; Gonzalez Suarez, R.; Kalogeropoulos, A.; Maes, M.; Olbrechts, A.; Van Doninck, W.; Van Mulders, P.; Van Onsem, G. P.; Villella, I.; Clerbaux, B.; De Lentdecker, G.; Dero, V.; Gay, A. P. R.; Hreus, T.; Léonard, A.; Marage, P. E.; Mohammadi, A.; Reis, T.; Thomas, L.; Vander Marcken, G.; Vander Velde, C.; Vanlaer, P.; Wang, J.; Adler, V.; Beernaert, K.; Cimmino, A.; Costantini, S.; Garcia, G.; Grunewald, M.; Klein, B.; Lellouch, J.; Marinov, A.; Mccartin, J.; Ocampo Rios, A. A.; Ryckbosch, D.; Strobbe, N.; Thyssen, F.; Tytgat, M.; Verwilligen, P.; Walsh, S.; Yazgan, E.; Zaganidis, N.; Basegmez, S.; Bruno, G.; Castello, R.; Ceard, L.; Delaere, C.; du Pree, T.; Favart, D.; Forthomme, L.; Giammanco, A.; Hollar, J.; Lemaitre, V.; Liao, J.; Militaru, O.; Nuttens, C.; Pagano, D.; Pin, A.; Piotrzkowski, K.; Schul, N.; Vizan Garcia, J. M.; Beliy, N.; Caebergs, T.; Daubie, E.; Hammad, G. H.; Alves, G. A.; Correa Martins, M.; De Jesus Damiao, D.; Martins, T.; Pol, M. E.; Souza, M. H. G.; Aldá, W. L.; Carvalho, W.; Custódio, A.; Da Costa, E. M.; De Oliveira Martins, C.; Fonseca De Souza, S.; Matos Figueiredo, D.; Mundim, L.; Nogima, H.; Oguri, V.; Prado Da Silva, W. L.; Santoro, A.; Soares Jorge, L.; Sznajder, A.; Anjos, T. S.; Bernardes, C. A.; Dias, F. A.; Fernandez Perez Tomei, T. R.; Gregores, E. M.; Lagana, C.; Marinho, F.; Mercadante, P. G.; Novaes, S. F.; Padula, Sandra S.; Genchev, V.; Iaydjiev, P.; Piperov, S.; Rodozov, M.; Stoykova, S.; Sultanov, G.; Tcholakov, V.; Trayanov, R.; Vutova, M.; Dimitrov, A.; Hadjiiska, R.; Kozhuharov, V.; Litov, L.; Pavlov, B.; Petkov, P.; Bian, J. G.; Chen, G. M.; Chen, H. S.; Jiang, C. H.; Liang, D.; Liang, S.; Meng, X.; Tao, J.; Wang, J.; Wang, X.; Wang, Z.; Xiao, H.; Xu, M.; Zang, J.; Zhang, Z.; Asawatangtrakuldee, C.; Ban, Y.; Guo, Y.; Li, W.; Liu, S.; Mao, Y.; Qian, S. J.; Teng, H.; Wang, D.; Zhang, L.; Zou, W.; Avila, C.; Gomez, J. P.; Gomez Moreno, B.; Osorio Oliveros, A. F.; Sanabria, J. C.; Godinovic, N.; Lelas, D.; Plestina, R.; Polic, D.; Puljak, I.; Antunovic, Z.; Kovac, M.; Brigljevic, V.; Duric, S.; Kadija, K.; Luetic, J.; Morovic, S.; Attikis, A.; Galanti, M.; Mavromanolakis, G.; Mousa, J.; Nicolaou, C.; Ptochos, F.; Razis, P. A.; Finger, M.; Finger, M.; Assran, Y.; Elgammal, S.; Ellithi Kamel, A.; Mahmoud, M. A.; Radi, A.; Kadastik, M.; Müntel, M.; Raidal, M.; Rebane, L.; Tiko, A.; Eerola, P.; Fedi, G.; Voutilainen, M.; Härkönen, J.; Heikkinen, A.; Karimäki, V.; Kinnunen, R.; Kortelainen, M. J.; Lampén, T.; Lassila-Perini, K.; Lehti, S.; Lindén, T.; Luukka, P.; Mäenpää, T.; Peltola, T.; Tuominen, E.; Tuominiemi, J.; Tuovinen, E.; Ungaro, D.; Wendland, L.; Banzuzi, K.; Karjalainen, A.; Korpela, A.; Tuuva, T.; Besancon, M.; Choudhury, S.; Dejardin, M.; Denegri, D.; Fabbro, B.; Faure, J. L.; Ferri, F.; Ganjour, S.; Givernaud, A.; Gras, P.; Hamel de Monchenault, G.; Jarry, P.; Locci, E.; Malcles, J.; Millischer, L.; Nayak, A.; Rander, J.; Rosowsky, A.; Shreyber, I.; Titov, M.; Baffioni, S.; Beaudette, F.; Benhabib, L.; Bianchini, L.; Bluj, M.; Broutin, C.; Busson, P.; Charlot, C.; Daci, N.; Dahms, T.; Dobrzynski, L.; Granier de Cassagnac, R.; Haguenauer, M.; Miné, P.; Mironov, C.; Naranjo, I. N.; Nguyen, M.; Ochando, C.; Paganini, P.; Sabes, D.; Salerno, R.; Sirois, Y.; Veelken, C.; Zabi, A.; Agram, J. -L.; Andrea, J.; Bloch, D.; Bodin, D.; Brom, J. -M.; Cardaci, M.; Chabert, E. C.; Collard, C.; Conte, E.; Drouhin, F.; Ferro, C.; Fontaine, J. -C.; Gelé, D.; Goerlach, U.; Juillot, P.; Le Bihan, A. -C.; Van Hove, P.; Fassi, F.; Mercier, D.; Beauceron, S.; Beaupere, N.; Bondu, O.; Boudoul, G.; Chasserat, J.; Chierici, R.; Contardo, D.; Depasse, P.; El Mamouni, H.; Fay, J.; Gascon, S.; Gouzevitch, M.; Ille, B.; Kurca, T.; Lethuillier, M.; Mirabito, L.; Perries, S.; Sgandurra, L.; Sordini, V.; Tschudi, Y.; Verdier, P.; Viret, S.; Tsamalaidze, Z.; Anagnostou, G.; Autermann, C.; Beranek, S.; Edelhoff, M.; Feld, L.; Heracleous, N.; Hindrichs, O.; Jussen, R.; Klein, K.; Merz, J.; Ostapchuk, A.; Perieanu, A.; Raupach, F.; Sammet, J.; Schael, S.; Sprenger, D.; Weber, H.; Wittmer, B.; Zhukov, V.; Ata, M.; Caudron, J.; Dietz-Laursonn, E.; Duchardt, D.; Erdmann, M.; Fischer, R.; Güth, A.; Hebbeker, T.; Heidemann, C.; Hoepfner, K.; Klingebiel, D.; Kreuzer, P.; Merschmeyer, M.; Meyer, A.; Olschewski, M.; Papacz, P.; Pieta, H.; Reithler, H.; Schmitz, S. A.; Sonnenschein, L.; Steggemann, J.; Teyssier, D.; Weber, M.; Bontenackels, M.; Cherepanov, V.; Erdogan, Y.; Flügge, G.; Geenen, H.; Geisler, M.; Haj Ahmad, W.; Hoehle, F.; Kargoll, B.; Kress, T.; Kuessel, Y.; Lingemann, J.; Nowack, A.; Perchalla, L.; Pooth, O.; Sauerland, P.; Stahl, A.; Aldaya Martin, M.; Behr, J.; Behrenhoff, W.; Behrens, U.; Bergholz, M.; Bethani, A.; Borras, K.; Burgmeier, A.; Cakir, A.; Calligaris, L.; Campbell, A.; Castro, E.; Costanza, F.; Dammann, D.; Diez Pardos, C.; Eckerlin, G.; Eckstein, D.; Flucke, G.; Geiser, A.; Glushkov, I.; Gunnellini, P.; Habib, S.; Hauk, J.; Hellwig, G.; Jung, H.; Kasemann, M.; Katsas, P.; Kleinwort, C.; Kluge, H.; Knutsson, A.; Krämer, M.; Krücker, D.; Kuznetsova, E.; Lange, W.; Lohmann, W.; Lutz, B.; Mankel, R.; Marfin, I.; Marienfeld, M.; Melzer-Pellmann, I. -A.; Meyer, A. B.; Mnich, J.; Mussgiller, A.; Naumann-Emme, S.; Novgorodova, O.; Olzem, J.; Perrey, H.; Petrukhin, A.; Pitzl, D.; Raspereza, A.; Ribeiro Cipriano, P. M.; Riedl, C.; Ron, E.; Rosin, M.; Salfeld-Nebgen, J.; Schmidt, R.; Schoerner-Sadenius, T.; Sen, N.; Spiridonov, A.; Stein, M.; Walsh, R.; Wissing, C.; Blobel, V.; Draeger, J.; Enderle, H.; Erfle, J.; Gebbert, U.; Görner, M.; Hermanns, T.; Höing, R. S.; Kaschube, K.; Kaussen, G.; Kirschenmann, H.; Klanner, R.; Lange, J.; Mura, B.; Nowak, F.; Peiffer, T.; Pietsch, N.; Rathjens, D.; Sander, C.; Schettler, H.; Schleper, P.; Schlieckau, E.; Schmidt, A.; Schröder, M.; Schum, T.; Seidel, M.; Sola, V.; Stadie, H.; Steinbrück, G.; Thomsen, J.; Vanelderen, L.; Barth, C.; Berger, J.; Böser, C.; Chwalek, T.; De Boer, W.; Descroix, A.; Dierlamm, A.; Feindt, M.; Guthoff, M.; Hackstein, C.; Hartmann, F.; Hauth, T.; Heinrich, M.; Held, H.; Hoffmann, K. H.; Husemann, U.; Katkov, I.; Komaragiri, J. R.; Lobelle Pardo, P.; Martschei, D.; Mueller, S.; Müller, Th.; Niegel, M.; Nürnberg, A.; Oberst, O.; Oehler, A.; Ott, J.; Quast, G.; Rabbertz, K.; Ratnikov, F.; Ratnikova, N.; Röcker, S.; Schilling, F. -P.; Schott, G.; Simonis, H. J.; Stober, F. M.; Troendle, D.; Ulrich, R.; Wagner-Kuhr, J.; Wayand, S.; Weiler, T.; Zeise, M.; Daskalakis, G.; Geralis, T.; Kesisoglou, S.; Kyriakis, A.; Loukas, D.; Manolakos, I.; Markou, A.; Markou, C.; Mavrommatis, C.; Ntomari, E.; Gouskos, L.; Mertzimekis, T. J.; Panagiotou, A.; Saoulidou, N.; Evangelou, I.; Foudas, C.; Kokkas, P.; Manthos, N.; Papadopoulos, I.; Patras, V.; Bencze, G.; Hajdu, C.; Hidas, P.; Horvath, D.; Sikler, F.; Veszpremi, V.; Vesztergombi, G.; Beni, N.; Czellar, S.; Molnar, J.; Palinkas, J.; Szillasi, Z.; Karancsi, J.; Raics, P.; Trocsanyi, Z. L.; Ujvari, B.; Beri, S. B.; Bhatnagar, V.; Dhingra, N.; Gupta, R.; Kaur, M.; Mehta, M. Z.; Nishu, N.; Saini, L. K.; Sharma, A.; Singh, J. 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M.; Lista, L.; Meola, S.; Merola, M.; Paolucci, P.; Azzi, P.; Bacchetta, N.; Bellan, P.; Bisello, D.; Branca, A.; Carlin, R.; Checchia, P.; Dorigo, T.; Dosselli, U.; Gasparini, F.; Gasparini, U.; Gozzelino, A.; Kanishchev, K.; Lacaprara, S.; Lazzizzera, I.; Margoni, M.; Meneguzzo, A. T.; Nespolo, M.; Pazzini, J.; Ronchese, P.; Simonetto, F.; Torassa, E.; Vanini, S.; Zotto, P.; Zumerle, G.; Gabusi, M.; Ratti, S. P.; Riccardi, C.; Torre, P.; Vitulo, P.; Biasini, M.; Bilei, G. M.; Fanò, L.; Lariccia, P.; Mantovani, G.; Menichelli, M.; Nappi, A.; Romeo, F.; Saha, A.; Santocchia, A.; Spiezia, A.; Taroni, S.; Azzurri, P.; Bagliesi, G.; Bernardini, J.; Boccali, T.; Broccolo, G.; Castaldi, R.; D’Agnolo, R. T.; Dell’Orso, R.; Fiori, F.; Foà, L.; Giassi, A.; Kraan, A.; Ligabue, F.; Lomtadze, T.; Martini, L.; Messineo, A.; Palla, F.; Rizzi, A.; Serban, A. T.; Spagnolo, P.; Squillacioti, P.; Tenchini, R.; Tonelli, G.; Venturi, A.; Verdini, P. G.; Barone, L.; Cavallari, F.; Del Re, D.; Diemoz, M.; Fanelli, C.; Grassi, M.; Longo, E.; Meridiani, P.; Micheli, F.; Nourbakhsh, S.; Organtini, G.; Paramatti, R.; Rahatlou, S.; Sigamani, M.; Soffi, L.; Amapane, N.; Arcidiacono, R.; Argiro, S.; Arneodo, M.; Biino, C.; Cartiglia, N.; Costa, M.; Demaria, N.; Mariotti, C.; Maselli, S.; Migliore, E.; Monaco, V.; Musich, M.; Obertino, M. M.; Pastrone, N.; Pelliccioni, M.; Potenza, A.; Romero, A.; Ruspa, M.; Sacchi, R.; Solano, A.; Staiano, A.; Vilela Pereira, A.; Belforte, S.; Candelise, V.; Casarsa, M.; Cossutti, F.; Della Ricca, G.; Gobbo, B.; Marone, M.; Montanino, D.; Penzo, A.; Schizzi, A.; Heo, S. G.; Kim, T. Y.; Nam, S. K.; Chang, S.; Kim, D. H.; Kim, G. N.; Kong, D. J.; Park, H.; Ro, S. R.; Son, D. C.; Son, T.; Kim, J. Y.; Kim, Zero J.; Song, S.; Choi, S.; Gyun, D.; Hong, B.; Jo, M.; Kim, H.; Kim, T. J.; Lee, K. S.; Moon, D. H.; Park, S. K.; Choi, M.; Kim, J. H.; Park, C.; Park, I. 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U.; Mulders, M.; Musella, P.; Nesvold, E.; Orimoto, T.; Orsini, L.; Palencia Cortezon, E.; Perez, E.; Perrozzi, L.; Petrilli, A.; Pfeiffer, A.; Pierini, M.; Pimiä, M.; Piparo, D.; Polese, G.; Quertenmont, L.; Racz, A.; Reece, W.; Rodrigues Antunes, J.; Rolandi, G.; Rovelli, C.; Rovere, M.; Sakulin, H.; Santanastasio, F.; Schäfer, C.; Schwick, C.; Segoni, I.; Sekmen, S.; Sharma, A.; Siegrist, P.; Silva, P.; Simon, M.; Sphicas, P.; Spiga, D.; Tsirou, A.; Veres, G. I.; Vlimant, J. R.; Wöhri, H. K.; Worm, S. D.; Zeuner, W. D.; Bertl, W.; Deiters, K.; Erdmann, W.; Gabathuler, K.; Horisberger, R.; Ingram, Q.; Kaestli, H. C.; König, S.; Kotlinski, D.; Langenegger, U.; Meier, F.; Renker, D.; Rohe, T.; Sibille, J.; Bäni, L.; Bortignon, P.; Buchmann, M. A.; Casal, B.; Chanon, N.; Deisher, A.; Dissertori, G.; Dittmar, M.; Donegà, M.; Dünser, M.; Eugster, J.; Freudenreich, K.; Grab, C.; Hits, D.; Lecomte, P.; Lustermann, W.; Marini, A. C.; Martinez Ruiz del Arbol, P.; Mohr, N.; Moortgat, F.; Nägeli, C.; Nef, P.; Nessi-Tedaldi, F.; Pandolfi, F.; Pape, L.; Pauss, F.; Peruzzi, M.; Ronga, F. J.; Rossini, M.; Sala, L.; Sanchez, A. K.; Starodumov, A.; Stieger, B.; Takahashi, M.; Tauscher, L.; Thea, A.; Theofilatos, K.; Treille, D.; Urscheler, C.; Wallny, R.; Weber, H. A.; Wehrli, L.; Amsler, C.; Chiochia, V.; De Visscher, S.; Favaro, C.; Ivova Rikova, M.; Millan Mejias, B.; Otiougova, P.; Robmann, P.; Snoek, H.; Tupputi, S.; Verzetti, M.; Chang, Y. H.; Chen, K. H.; Kuo, C. M.; Li, S. W.; Lin, W.; Liu, Z. K.; Lu, Y. J.; Mekterovic, D.; Singh, A. P.; Volpe, R.; Yu, S. S.; Bartalini, P.; Chang, P.; Chang, Y. H.; Chang, Y. W.; Chao, Y.; Chen, K. F.; Dietz, C.; Grundler, U.; Hou, W. -S.; Hsiung, Y.; Kao, K. Y.; Lei, Y. J.; Lu, R. -S.; Majumder, D.; Petrakou, E.; Shi, X.; Shiu, J. G.; Tzeng, Y. M.; Wan, X.; Wang, M.; Asavapibhop, B.; Srimanobhas, N.; Adiguzel, A.; Bakirci, M. 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W.; Olaiya, E.; Petyt, D.; Radburn Smith, B. C.; Shepherd-Themistocleous, C. H.; Tomalin, I. R.; Womersley, W. J.; Bainbridge, R.; Ball, G.; Beuselinck, R.; Buchmuller, O.; Burton, D. L.; Colling, D.; Cripps, N.; Cutajar, M.; Dauncey, P.; Davies, G.; Della Negra, M.; Ferguson, W.; Fulcher, J.; Futyan, D.; Gilbert, A.; Guneratne Bryer, A.; Hall, G.; Hatherell, Z.; Hays, J.; Iles, G.; Jarvis, M.; Karapostoli, G.; Lyons, L.; Magnan, A. -M.; Marrouche, J.; Mathias, B.; Nandi, R.; Nash, J.; Nikitenko, A.; Papageorgiou, A.; Pela, J.; Pesaresi, M.; Petridis, K.; Pioppi, M.; Raymond, D. M.; Rogerson, S.; Rose, A.; Ryan, M. J.; Seez, C.; Sharp, P.; Sparrow, A.; Stoye, M.; Tapper, A.; Vazquez Acosta, M.; Virdee, T.; Wakefield, S.; Wardle, N.; Whyntie, T.; Chadwick, M.; Cole, J. E.; Hobson, P. R.; Khan, A.; Kyberd, P.; Leggat, D.; Leslie, D.; Martin, W.; Reid, I. D.; Symonds, P.; Teodorescu, L.; Turner, M.; Hatakeyama, K.; Liu, H.; Scarborough, T.; Charaf, O.; Henderson, C.; Rumerio, P.; Avetisyan, A.; Bose, T.; Fantasia, C.; Heister, A.; St. John, J.; Lawson, P.; Lazic, D.; Rohlf, J.; Sperka, D.; Sulak, L.; Alimena, J.; Bhattacharya, S.; Cutts, D.; Demiragli, Z.; Ferapontov, A.; Heintz, U.; Jabeen, S.; Kukartsev, G.; Laird, E.; Landsberg, G.; Luk, M.; Narain, M.; Nguyen, D.; Segala, M.; Sinthuprasith, T.; Speer, T.; Tsang, K. V.; Breedon, R.; Breto, G.; Calderon De La Barca Sanchez, M.; Chauhan, S.; Chertok, M.; Conway, J.; Conway, R.; Cox, P. T.; Dolen, J.; Erbacher, R.; Gardner, M.; Houtz, R.; Ko, W.; Kopecky, A.; Lander, R.; Mall, O.; Miceli, T.; Pellett, D.; Ricci-Tam, F.; Rutherford, B.; Searle, M.; Smith, J.; Squires, M.; Tripathi, M.; Vasquez Sierra, R.; Yohay, R.; Andreev, V.; Cline, D.; Cousins, R.; Duris, J.; Erhan, S.; Everaerts, P.; Farrell, C.; Hauser, J.; Ignatenko, M.; Jarvis, C.; Plager, C.; Rakness, G.; Schlein, P.; Traczyk, P.; Valuev, V.; Weber, M.; Babb, J.; Clare, R.; Dinardo, M. E.; Ellison, J.; Gary, J. W.; Giordano, F.; Hanson, G.; Jeng, G. Y.; Liu, H.; Long, O. R.; Luthra, A.; Nguyen, H.; Paramesvaran, S.; Sturdy, J.; Sumowidagdo, S.; Wilken, R.; Wimpenny, S.; Andrews, W.; Branson, J. G.; Cerati, G. B.; Cittolin, S.; Evans, D.; Golf, F.; Holzner, A.; Kelley, R.; Lebourgeois, M.; Letts, J.; Macneill, I.; Mangano, B.; Padhi, S.; Palmer, C.; Petrucciani, G.; Pieri, M.; Sani, M.; Sharma, V.; Simon, S.; Sudano, E.; Tadel, M.; Tu, Y.; Vartak, A.; Wasserbaech, S.; Würthwein, F.; Yagil, A.; Yoo, J.; Barge, D.; Bellan, R.; Campagnari, C.; D’Alfonso, M.; Danielson, T.; Flowers, K.; Geffert, P.; Incandela, J.; Justus, C.; Kalavase, P.; Koay, S. A.; Kovalskyi, D.; Krutelyov, V.; Lowette, S.; Mccoll, N.; Pavlunin, V.; Rebassoo, F.; Ribnik, J.; Richman, J.; Rossin, R.; Stuart, D.; To, W.; West, C.; Apresyan, A.; Bornheim, A.; Chen, Y.; Di Marco, E.; Duarte, J.; Gataullin, M.; Ma, Y.; Mott, A.; Newman, H. B.; Rogan, C.; Spiropulu, M.; Timciuc, V.; Veverka, J.; Wilkinson, R.; Xie, S.; Yang, Y.; Zhu, R. Y.; Akgun, B.; Azzolini, V.; Calamba, A.; Carroll, R.; Ferguson, T.; Iiyama, Y.; Jang, D. W.; Liu, Y. F.; Paulini, M.; Vogel, H.; Vorobiev, I.; Cumalat, J. P.; Drell, B. R.; Ford, W. T.; Gaz, A.; Luiggi Lopez, E.; Smith, J. G.; Stenson, K.; Ulmer, K. A.; Wagner, S. R.; Alexander, J.; Chatterjee, A.; Eggert, N.; Gibbons, L. K.; Heltsley, B.; Khukhunaishvili, A.; Kreis, B.; Mirman, N.; Nicolas Kaufman, G.; Patterson, J. R.; Ryd, A.; Salvati, E.; Sun, W.; Teo, W. D.; Thom, J.; Thompson, J.; Tucker, J.; Vaughan, J.; Weng, Y.; Winstrom, L.; Wittich, P.; Winn, D.; Abdullin, S.; Albrow, M.; Anderson, J.; Bauerdick, L. A. T.; Beretvas, A.; Berryhill, J.; Bhat, P. C.; Bloch, I.; Burkett, K.; Butler, J. N.; Chetluru, V.; Cheung, H. W. K.; Chlebana, F.; Elvira, V. D.; Fisk, I.; Freeman, J.; Gao, Y.; Green, D.; Gutsche, O.; Hanlon, J.; Harris, R. M.; Hirschauer, J.; Hooberman, B.; Jindariani, S.; Johnson, M.; Joshi, U.; Kilminster, B.; Klima, B.; Kunori, S.; Kwan, S.; Leonidopoulos, C.; Linacre, J.; Lincoln, D.; Lipton, R.; Lykken, J.; Maeshima, K.; Marraffino, J. M.; Maruyama, S.; Mason, D.; McBride, P.; Mishra, K.; Mrenna, S.; Musienko, Y.; Newman-Holmes, C.; O’Dell, V.; Prokofyev, O.; Sexton-Kennedy, E.; Sharma, S.; Spalding, W. J.; Spiegel, L.; Taylor, L.; Tkaczyk, S.; Tran, N. V.; Uplegger, L.; Vaandering, E. W.; Vidal, R.; Whitmore, J.; Wu, W.; Yang, F.; Yumiceva, F.; Yun, J. C.; Acosta, D.; Avery, P.; Bourilkov, D.; Chen, M.; Cheng, T.; Das, S.; De Gruttola, M.; Di Giovanni, G. P.; Dobur, D.; Drozdetskiy, A.; Field, R. D.; Fisher, M.; Fu, Y.; Furic, I. K.; Gartner, J.; Hugon, J.; Kim, B.; Konigsberg, J.; Korytov, A.; Kropivnitskaya, A.; Kypreos, T.; Low, J. F.; Matchev, K.; Milenovic, P.; Mitselmakher, G.; Muniz, L.; Park, M.; Remington, R.; Rinkevicius, A.; Sellers, P.; Skhirtladze, N.; Snowball, M.; Yelton, J.; Zakaria, M.; Gaultney, V.; Hewamanage, S.; Lebolo, L. M.; Linn, S.; Markowitz, P.; Martinez, G.; Rodriguez, J. L.; Adams, T.; Askew, A.; Bochenek, J.; Chen, J.; Diamond, B.; Gleyzer, S. V.; Haas, J.; Hagopian, S.; Hagopian, V.; Jenkins, M.; Johnson, K. F.; Prosper, H.; Veeraraghavan, V.; Weinberg, M.; Baarmand, M. M.; Dorney, B.; Hohlmann, M.; Kalakhety, H.; Vodopiyanov, I.; Adams, M. R.; Anghel, I. M.; Apanasevich, L.; Bai, Y.; Bazterra, V. E.; Betts, R. R.; Bucinskaite, I.; Callner, J.; Cavanaugh, R.; Evdokimov, O.; Gauthier, L.; Gerber, C. E.; Hofman, D. J.; Khalatyan, S.; Lacroix, F.; Malek, M.; O’Brien, C.; Silkworth, C.; Strom, D.; Turner, P.; Varelas, N.; Akgun, U.; Albayrak, E. A.; Bilki, B.; Clarida, W.; Duru, F.; Merlo, J. -P.; Mermerkaya, H.; Mestvirishvili, A.; Moeller, A.; Nachtman, J.; Newsom, C. R.; Norbeck, E.; Onel, Y.; Ozok, F.; Sen, S.; Tan, P.; Tiras, E.; Wetzel, J.; Yetkin, T.; Yi, K.; Barnett, B. A.; Blumenfeld, B.; Bolognesi, S.; Fehling, D.; Giurgiu, G.; Gritsan, A. V.; Guo, Z. J.; Hu, G.; Maksimovic, P.; Rappoccio, S.; Swartz, M.; Whitbeck, A.; Baringer, P.; Bean, A.; Benelli, G.; Kenny, R. P.; Murray, M.; Noonan, D.; Sanders, S.; Stringer, R.; Tinti, G.; Wood, J. S.; Zhukova, V.; Barfuss, A. F.; Bolton, T.; Chakaberia, I.; Ivanov, A.; Khalil, S.; Makouski, M.; Maravin, Y.; Shrestha, S.; Svintradze, I.; Gronberg, J.; Lange, D.; Wright, D.; Baden, A.; Boutemeur, M.; Calvert, B.; Eno, S. C.; Gomez, J. A.; Hadley, N. J.; Kellogg, R. G.; Kirn, M.; Kolberg, T.; Lu, Y.; Marionneau, M.; Mignerey, A. C.; Pedro, K.; Peterman, A.; Skuja, A.; Temple, J.; Tonjes, M. B.; Tonwar, S. C.; Twedt, E.; Apyan, A.; Bauer, G.; Bendavid, J.; Busza, W.; Butz, E.; Cali, I. A.; Chan, M.; Dutta, V.; Gomez Ceballos, G.; Goncharov, M.; Hahn, K. A.; Kim, Y.; Klute, M.; Krajczar, K.; Luckey, P. D.; Ma, T.; Nahn, S.; Paus, C.; Ralph, D.; Roland, C.; Roland, G.; Rudolph, M.; Stephans, G. S. F.; Stöckli, F.; Sumorok, K.; Sung, K.; Velicanu, D.; Wenger, E. A.; Wolf, R.; Wyslouch, B.; Yang, M.; Yilmaz, Y.; Yoon, A. S.; Zanetti, M.; Cooper, S. I.; Dahmes, B.; De Benedetti, A.; Franzoni, G.; Gude, A.; Kao, S. C.; Klapoetke, K.; Kubota, Y.; Mans, J.; Pastika, N.; Rusack, R.; Sasseville, M.; Singovsky, A.; Tambe, N.; Turkewitz, J.; Cremaldi, L. M.; Kroeger, R.; Perera, L.; Rahmat, R.; Sanders, D. A.; Avdeeva, E.; Bloom, K.; Bose, S.; Butt, J.; Claes, D. R.; Dominguez, A.; Eads, M.; Keller, J.; Kravchenko, I.; Lazo-Flores, J.; Malbouisson, H.; Malik, S.; Snow, G. R.; Godshalk, A.; Iashvili, I.; Jain, S.; Kharchilava, A.; Kumar, A.; Alverson, G.; Barberis, E.; Baumgartel, D.; Chasco, M.; Haley, J.; Nash, D.; Trocino, D.; Wood, D.; Zhang, J.; Anastassov, A.; Kubik, A.; Mucia, N.; Odell, N.; Ofierzynski, R. A.; Pollack, B.; Pozdnyakov, A.; Schmitt, M.; Stoynev, S.; Velasco, M.; Won, S.; Antonelli, L.; Berry, D.; Brinkerhoff, A.; Chan, K. M.; Hildreth, M.; Jessop, C.; Karmgard, D. J.; Kolb, J.; Lannon, K.; Luo, W.; Lynch, S.; Marinelli, N.; Morse, D. M.; Pearson, T.; Planer, M.; Ruchti, R.; Slaunwhite, J.; Valls, N.; Wayne, M.; Wolf, M.; Bylsma, B.; Durkin, L. S.; Hill, C.; Hughes, R.; Kotov, K.; Ling, T. Y.; Puigh, D.; Rodenburg, M.; Vuosalo, C.; Williams, G.; Winer, B. L.; Adam, N.; Berry, E.; Elmer, P.; Gerbaudo, D.; Halyo, V.; Hebda, P.; Hegeman, J.; Hunt, A.; Jindal, P.; Lopes Pegna, D.; Lujan, P.; Marlow, D.; Medvedeva, T.; Mooney, M.; Olsen, J.; Piroué, P.; Quan, X.; Raval, A.; Safdi, B.; Saka, H.; Stickland, D.; Tully, C.; Werner, J. S.; Zuranski, A.; Brownson, E.; Lopez, A.; Mendez, H.; Ramirez Vargas, J. E.; Alagoz, E.; Barnes, V. E.; Benedetti, D.; Bolla, G.; Bortoletto, D.; De Mattia, M.; Everett, A.; Hu, Z.; Jones, M.; Koybasi, O.; Kress, M.; Laasanen, A. T.; Leonardo, N.; Maroussov, V.; Merkel, P.; Miller, D. H.; Neumeister, N.; Shipsey, I.; Silvers, D.; Svyatkovskiy, A.; Vidal Marono, M.; Yoo, H. D.; Zablocki, J.; Zheng, Y.; Guragain, S.; Parashar, N.; Adair, A.; Boulahouache, C.; Ecklund, K. M.; Geurts, F. J. M.; Li, W.; Padley, B. P.; Redjimi, R.; Roberts, J.; Zabel, J.; Betchart, B.; Bodek, A.; Chung, Y. S.; Covarelli, R.; de Barbaro, P.; Demina, R.; Eshaq, Y.; Ferbel, T.; Garcia-Bellido, A.; Goldenzweig, P.; Han, J.; Harel, A.; Miner, D. C.; Vishnevskiy, D.; Zielinski, M.; Bhatti, A.; Ciesielski, R.; Demortier, L.; Goulianos, K.; Lungu, G.; Malik, S.; Mesropian, C.; Arora, S.; Barker, A.; Chou, J. P.; Contreras-Campana, C.; Contreras-Campana, E.; Duggan, D.; Ferencek, D.; Gershtein, Y.; Gray, R.; Halkiadakis, E.; Hidas, D.; Lath, A.; Panwalkar, S.; Park, M.; Patel, R.; Rekovic, V.; Robles, J.; Rose, K.; Salur, S.; Schnetzer, S.; Seitz, C.; Somalwar, S.; Stone, R.; Thomas, S.; Cerizza, G.; Hollingsworth, M.; Spanier, S.; Yang, Z. C.; York, A.; Eusebi, R.; Flanagan, W.; Gilmore, J.; Kamon, T.; Khotilovich, V.; Montalvo, R.; Osipenkov, I.; Pakhotin, Y.; Perloff, A.; Roe, J.; Safonov, A.; Sakuma, T.; Sengupta, S.; Suarez, I.; Tatarinov, A.; Toback, D.; Akchurin, N.; Damgov, J.; Dragoiu, C.; Dudero, P. R.; Jeong, C.; Kovitanggoon, K.; Lee, S. W.; Libeiro, T.; Roh, Y.; Volobouev, I.; Appelt, E.; Delannoy, A. G.; Florez, C.; Greene, S.; Gurrola, A.; Johns, W.; Kurt, P.; Maguire, C.; Melo, A.; Sharma, M.; Sheldon, P.; Snook, B.; Tuo, S.; Velkovska, J.; Arenton, M. W.; Balazs, M.; Boutle, S.; Cox, B.; Francis, B.; Goodell, J.; Hirosky, R.; Ledovskoy, A.; Lin, C.; Neu, C.; Wood, J.; Gollapinni, S.; Harr, R.; Karchin, P. E.; Kottachchi Kankanamge Don, C.; Lamichhane, P.; Sakharov, A.; Anderson, M.; Belknap, D.; Borrello, L.; Carlsmith, D.; Cepeda, M.; Dasu, S.; Friis, E.; Gray, L.; Grogg, K. S.; Grothe, M.; Hall-Wilton, R.; Herndon, M.; Hervé, A.; Klabbers, P.; Klukas, J.; Lanaro, A.; Lazaridis, C.; Leonard, J.; Loveless, R.; Mohapatra, A.; Ojalvo, I.; Palmonari, F.; Pierro, G. A.; Ross, I.; Savin, A.; Smith, W. H.; Swanson, J.

    2013-01-01

    A search for supersymmetry in final states with jets and missing transverse energy is performed in pp collisions at a centre-of-mass energy of sqrt(s) = 7 TeV. The data sample corresponds to an integrated luminosity of 4.98 inverse femtobarns collected by the CMS experiment at the LHC. In this search, a dimensionless kinematic variable, alphaT, is used as the main discriminator between events with genuine and misreconstructed missing transverse energy. The search is performed in a signal region that is binned in the scalar sum of the transverse energy of jets and the number of jets identified as originating from a bottom quark. No excess of events over the standard model expectation is found. Exclusion limits are set in the parameter space of the constrained minimal supersymmetric extension of the standard model, and also in simplified models, with a special emphasis on compressed spectra and third-generation scenarios.

  6. Levy Foraging in a Dynamic Environment – Extending the Levy Search

    Directory of Open Access Journals (Sweden)

    Vincenzo Fioriti

    2015-07-01

    Full Text Available A common task for robots is the patrolling of an unknown area with inadequate information about target locations. Under these circumstances it has been suggested that animal foraging could provide an optimal or at least sub-optimal search methodology, namely the Levy flight search. Although still in debate, it seems that predators somehow follow this search pattern when foraging, because it avoids being trapped in a local search if the food is beyond the sensory range. A Levy flight is a particular case of the random walk. Its displacements on a 2-D surface are drawn from the Pareto-Levy probability distribution, characterized by power law tails. The Levy flight search has many applications in optical material, ladars, optics, large database search, earthquake data analysis, location of DNA sites, human mobility, stock return analysis, online auctions, astronomy, ecology and biology. Almost all studies and simulations concerning the Levy flight foraging examine static or slowly moving (with respect to the forager uniformly distributed resources. Moreover, in recent works a small swarm of underwater autonomous vehicles has been used to test the standard Levy search in the underwater environment, with good results. In this paper we extend the classical Levy foraging framework taking into consideration a moving target allocated on a 2-D surface according to a radial probability distribution and comparing its performance with the random walk search. The metric used in the numerical simulations is the detection rate. Simulations include the sensor resolution, intended as the maximum detection distance of the forager from the target. Furthermore, contrarily to the usual Levy foraging framework, we use only one target. Results show that Levy flight outperforms the random walk if the sensor detection radius is not too small or too large. We also find the Levy flight in the velocity of the center of mass model of a fish school according the Kuramoto

  7. Search for Supersymmetry in 8 TeV Proton-Proton Collision Events with Bottom-Quark Jets and Missing Transverse Energy

    CERN Document Server

    Kreis, Benjamin

    A search for supersymmetry in a sample of proton-proton collision events with a center-of-mass energy of 8 TeV is presented. The sample, collected with the Compact Muon Solenoid detector at the Large Hadron Collider, corresponds to an integrated luminosity of 19.4 fb$^{−1}$. Events are required to have large missing transverse energy, at least three jets, and at least one identified bottom-quark jet. Numbers of events in exclusive bins of the scalar sum of jet transverse momentum values, missing transverse energy, and bottom-quark jet multiplicity are found to be consistent with the standard model expectations. The results are interpreted as 95$\\%$ confidence level upper limits on simplified supersymmetric models approximating gluino mediated bottom- and top-squark production.

  8. Secret Shoppers: The Stealth Applicant Search for Higher Education

    Science.gov (United States)

    Dupaul, Stephanie; Harris, Michael S.

    2012-01-01

    Stealth applicants who do not flow through the traditional admission funnel now represent nearly one-third of the national applicant pool. This study employs a consumer behavior framework to examine the behaviors of stealth applicants at a private university. The findings provide a rich illustration of how stealth applicants search for college.…

  9. Statistical energy as a tool for binning-free, multivariate goodness-of-fit tests, two-sample comparison and unfolding

    International Nuclear Information System (INIS)

    Aslan, B.; Zech, G.

    2005-01-01

    We introduce the novel concept of statistical energy as a statistical tool. We define statistical energy of statistical distributions in a similar way as for electric charge distributions. Charges of opposite sign are in a state of minimum energy if they are equally distributed. This property is used to check whether two samples belong to the same parent distribution, to define goodness-of-fit tests and to unfold distributions distorted by measurement. The approach is binning-free and especially powerful in multidimensional applications

  10. A procedure for searching the equilibrium core of a research reactor

    International Nuclear Information System (INIS)

    Bakri Arbie; Liem Peng Hong; Prayoto

    1996-01-01

    A procedure for searching the equilibrium core of a research reactor has been proposed. The searching procedure is based on the relaxation method and has been implemented in Batan-EQUIL-2D in-core fuel management code. The few-group neutron diffusion theory in 2-D, X-Y, and R-Z reactor geometries are adopted as the framework of the code. The successful applicability of the procedure for obtaining the new RSG-GAS (MPR-30) silicide equilibrium core was shown. (author)

  11. In search for a public health leadership competency framework to support leadership curriculum-a consensus study.

    Science.gov (United States)

    Czabanowska, Katarzyna; Smith, Tony; Könings, Karen D; Sumskas, Linas; Otok, Robert; Bjegovic-Mikanovic, Vesna; Brand, Helmut

    2014-10-01

    Competency-based education is increasingly popular, especially in the area of continuing professional development. Many competency frameworks have been developed; however, few address leadership competencies for European public health professionals. The aim of this study was to develop a public health leadership competency framework to inform a leadership curriculum for public health professionals. The framework was developed as part of the Leaders for European Public Health project-supported by the EU Lifelong Learning Programme. The study was carried out in three phases: a literature review, consensus development panel and Delphi survey. The public health leadership competency framework was initially developed from a literature review. A preliminary list of competencies was submitted to a panel of experts. Two consensus development panels were held to evaluate and make changes to the initial draft competency framework. Then two rounds of a Delphi survey were carried out in an effort to reach consensus. Both surveys were presented through Survey Monkey to members of the Association of the Schools of Public Health in the European Region Working Group on Innovation in Public Health Teaching and Education. The framework was developed consisting of 52 competencies organized into eight domains: Systems Thinking; Political Leadership; Collaborative Leadership: Building and Leading Interdisciplinary Teams; Leadership and Communication; Leading Change; Emotional Intelligence and Leadership in Team-based Organizations; Leadership, Organizational Learning and Development and Ethics and Professionalism. The framework can serve as a useful tool in identifying gaps in knowledge and skills, and shaping competency-based continuing professional development leadership curricula for public health professionals in Europe. © The Author 2013. Published by Oxford University Press on behalf of the European Public Health Association. All rights reserved.

  12. Building a Semantic Framework for eScience

    Science.gov (United States)

    Movva, S.; Ramachandran, R.; Maskey, M.; Li, X.

    2009-12-01

    The e-Science vision focuses on the use of advanced computing technologies to support scientists. Recent research efforts in this area have focused primarily on “enabling” use of infrastructure resources for both data and computational access especially in Geosciences. One of the existing gaps in the existing e-Science efforts has been the failure to incorporate stable semantic technologies within the design process itself. In this presentation, we describe our effort in designing a framework for e-Science built using Service Oriented Architecture. Our framework provides users capabilities to create science workflows and mine distributed data. Our e-Science framework is being designed around a mass market tool to promote reusability across many projects. Semantics is an integral part of this framework and our design goal is to leverage the latest stable semantic technologies. The use of these stable semantic technologies will provide the users of our framework the useful features such as: allow search engines to find their content with RDFa tags; create RDF triple data store for their content; create RDF end points to share with others; and semantically mash their content with other online content available as RDF end point.

  13. Searches for supersymmetry at high-energy colliders

    International Nuclear Information System (INIS)

    Feng, Jonathan L.; Grivaz, Jean-Francois; Nachtman, Jane

    2010-01-01

    This review summarizes the state of the art in searches for supersymmetry at colliders on the eve of the Large Hadron Collider era. Supersymmetry is unique among extensions of the standard model in being motivated by naturalness, dark matter, and force unification, both with and without gravity. At the same time, weak-scale supersymmetry encompasses a wide range of experimental signals that are also found in many other frameworks. Motivations for supersymmetry are recalled and the various models and their distinctive features are reviewed. Searches for neutral and charged Higgs bosons and standard-model superpartners at the high energy frontier are summarized comprehensively, considering both canonical and noncanonical supersymmetric models, and including results from the LEP collider at CERN, HERA at DESY, and the Fermilab Tevatron.

  14. Teaching excellence in nursing education: a caring framework.

    Science.gov (United States)

    Sawatzky, Jo-Ann V; Enns, Carol L; Ashcroft, Terri J; Davis, Penny L; Harder, B Nicole

    2009-01-01

    Nursing education plays a central role in the ability to practice effectively. It follows that an optimally educated nursing workforce begets optimal patient care. A framework for excellence in nursing education could guide the development of novice educators, establish the basis for evaluating teaching excellence, and provide the impetus for research in this area. However, a review of the social sciences and nursing literature as well as a search for existing models for teaching excellence revealed an apparent dearth of evidence specific to excellence in nursing education. Therefore, we developed the Caring Framework for Excellence in Nursing Education. This framework evolved from a review of the generic constructs that exemplify teaching excellence: excellence in teaching practice, teaching scholarship, and teaching leadership. Nursing is grounded in the ethic of caring. Hence, caring establishes the foundation for this uniquely nursing framework. Because a teaching philosophy is intimately intertwined with one's nursing philosophy and the ethic of caring, it is also fundamental to the caring framework. Ideally, this framework will contribute to excellence in nursing education and as a consequence excellence in nursing practice and optimal patient care.

  15. Search for supersymmetry in final states with missing transverse energy and 0, 1, 2, or at least 3 b-quark jets in 7 TeV pp collisions using the variable $\\alpha_T$

    CERN Document Server

    Chatrchyan, Serguei; Sirunyan, Albert M; Tumasyan, Armen; Adam, Wolfgang; Aguilo, Ernest; Bergauer, Thomas; Dragicevic, Marko; Erö, Janos; Fabjan, Christian; Friedl, Markus; Fruehwirth, Rudolf; Ghete, Vasile Mihai; Hammer, Josef; Hörmann, Natascha; Hrubec, Josef; Jeitler, Manfred; Kiesenhofer, Wolfgang; Knünz, Valentin; Krammer, Manfred; Krätschmer, Ilse; Liko, Dietrich; Mikulec, Ivan; Pernicka, Manfred; Rahbaran, Babak; Rohringer, Christine; Rohringer, Herbert; Schöfbeck, Robert; Strauss, Josef; Taurok, Anton; Waltenberger, Wolfgang; Walzel, Gerhard; Widl, Edmund; Wulz, Claudia-Elisabeth; Mossolov, Vladimir; Shumeiko, Nikolai; Suarez Gonzalez, Juan; Bansal, Monika; Bansal, Sunil; Cornelis, Tom; De Wolf, Eddi A; Janssen, Xavier; Luyckx, Sten; Mucibello, Luca; Ochesanu, Silvia; Roland, Benoit; Rougny, Romain; Selvaggi, Michele; Staykova, Zlatka; Van Haevermaet, Hans; Van Mechelen, Pierre; Van Remortel, Nick; Van Spilbeeck, Alex; Blekman, Freya; Blyweert, Stijn; D'Hondt, Jorgen; Gonzalez Suarez, Rebeca; Kalogeropoulos, Alexis; Maes, Michael; Olbrechts, Annik; Van Doninck, Walter; Van Mulders, Petra; Van Onsem, Gerrit Patrick; Villella, Ilaria; Clerbaux, Barbara; De Lentdecker, Gilles; Dero, Vincent; Gay, Arnaud; Hreus, Tomas; Léonard, Alexandre; Marage, Pierre Edouard; Mohammadi, Abdollah; Reis, Thomas; Thomas, Laurent; Vander Marcken, Gil; Vander Velde, Catherine; Vanlaer, Pascal; Wang, Jian; Adler, Volker; Beernaert, Kelly; Cimmino, Anna; Costantini, Silvia; Garcia, Guillaume; Grunewald, Martin; Klein, Benjamin; Lellouch, Jérémie; Marinov, Andrey; Mccartin, Joseph; Ocampo Rios, Alberto Andres; Ryckbosch, Dirk; Strobbe, Nadja; Thyssen, Filip; Tytgat, Michael; Verwilligen, Piet; Walsh, Sinead; Yazgan, Efe; Zaganidis, Nicolas; Basegmez, Suzan; Bruno, Giacomo; Castello, Roberto; Ceard, Ludivine; Delaere, Christophe; Du Pree, Tristan; Favart, Denis; Forthomme, Laurent; Giammanco, Andrea; Hollar, Jonathan; Lemaitre, Vincent; Liao, Junhui; Militaru, Otilia; Nuttens, Claude; Pagano, Davide; Pin, Arnaud; Piotrzkowski, Krzysztof; Schul, Nicolas; Vizan Garcia, Jesus Manuel; Beliy, Nikita; Caebergs, Thierry; Daubie, Evelyne; Hammad, Gregory Habib; Alves, Gilvan; Correa Martins Junior, Marcos; De Jesus Damiao, Dilson; Martins, Thiago; Pol, Maria Elena; Henrique Gomes E Souza, Moacyr; Aldá Júnior, Walter Luiz; Carvalho, Wagner; Custódio, Analu; Melo Da Costa, Eliza; De Oliveira Martins, Carley; Fonseca De Souza, Sandro; Matos Figueiredo, Diego; Mundim, Luiz; Nogima, Helio; Oguri, Vitor; Prado Da Silva, Wanda Lucia; Santoro, Alberto; Soares Jorge, Luana; Sznajder, Andre; Souza Dos Anjos, Tiago; Bernardes, Cesar Augusto; De Almeida Dias, Flavia; Tomei, Thiago; De Moraes Gregores, Eduardo; Lagana, Caio; Da Cunha Marinho, Franciole; Mercadante, Pedro G; Novaes, Sergio F; Padula, Sandra; Genchev, Vladimir; Iaydjiev, Plamen; Piperov, Stefan; Rodozov, Mircho; Stoykova, Stefka; Sultanov, Georgi; Tcholakov, Vanio; Trayanov, Rumen; Vutova, Mariana; Dimitrov, Anton; Hadjiiska, Roumyana; Kozhuharov, Venelin; Litov, Leander; Pavlov, Borislav; Petkov, Peicho; Bian, Jian-Guo; Chen, Guo-Ming; Chen, He-Sheng; Jiang, Chun-Hua; Liang, Dong; Liang, Song; Meng, Xiangwei; Tao, Junquan; Wang, Jian; Wang, Xianyou; Wang, Zheng; Xiao, Hong; Xu, Ming; Zang, Jingjing; Zhang, Zhen; Asawatangtrakuldee, Chayanit; Ban, Yong; Guo, Yifei; Li, Wenbo; Liu, Shuai; Mao, Yajun; Qian, Si-Jin; Teng, Haiyun; Wang, Dayong; Zhang, Linlin; Zou, Wei; Avila, Carlos; Gomez, Juan Pablo; Gomez Moreno, Bernardo; Osorio Oliveros, Andres Felipe; Sanabria, Juan Carlos; Godinovic, Nikola; Lelas, Damir; Plestina, Roko; Polic, Dunja; Puljak, Ivica; Antunovic, Zeljko; Kovac, Marko; Brigljevic, Vuko; Duric, Senka; Kadija, Kreso; Luetic, Jelena; Morovic, Srecko; Attikis, Alexandros; Galanti, Mario; Mavromanolakis, Georgios; Mousa, Jehad; Nicolaou, Charalambos; Ptochos, Fotios; Razis, Panos A; Finger, Miroslav; Finger Jr, Michael; Assran, Yasser; Elgammal, Sherif; Ellithi Kamel, Ali; Mahmoud, Mohammed; Radi, Amr; Kadastik, Mario; Müntel, Mait; Raidal, Martti; Rebane, Liis; Tiko, Andres; Eerola, Paula; Fedi, Giacomo; Voutilainen, Mikko; Härkönen, Jaakko; Heikkinen, Mika Aatos; Karimäki, Veikko; Kinnunen, Ritva; Kortelainen, Matti J; Lampén, Tapio; Lassila-Perini, Kati; Lehti, Sami; Lindén, Tomas; Luukka, Panja-Riina; Mäenpää, Teppo; Peltola, Timo; Tuominen, Eija; Tuominiemi, Jorma; Tuovinen, Esa; Ungaro, Donatella; Wendland, Lauri; Banzuzi, Kukka; Karjalainen, Ahti; Korpela, Arja; Tuuva, Tuure; Besancon, Marc; Choudhury, Somnath; Dejardin, Marc; Denegri, Daniel; Fabbro, Bernard; Faure, Jean-Louis; Ferri, Federico; Ganjour, Serguei; Givernaud, Alain; Gras, Philippe; Hamel de Monchenault, Gautier; Jarry, Patrick; Locci, Elizabeth; Malcles, Julie; Millischer, Laurent; Nayak, Aruna; Rander, John; Rosowsky, André; Shreyber, Irina; Titov, Maksym; Baffioni, Stephanie; Beaudette, Florian; Benhabib, Lamia; Bianchini, Lorenzo; Bluj, Michal; Broutin, Clementine; Busson, Philippe; Charlot, Claude; Daci, Nadir; Dahms, Torsten; Dobrzynski, Ludwik; Granier de Cassagnac, Raphael; Haguenauer, Maurice; Miné, Philippe; Mironov, Camelia; Naranjo, Ivo Nicolas; Nguyen, Matthew; Ochando, Christophe; Paganini, Pascal; Sabes, David; Salerno, Roberto; Sirois, Yves; Veelken, Christian; Zabi, Alexandre; Agram, Jean-Laurent; Andrea, Jeremy; Bloch, Daniel; Bodin, David; Brom, Jean-Marie; Cardaci, Marco; Chabert, Eric Christian; Collard, Caroline; Conte, Eric; Drouhin, Frédéric; Ferro, Cristina; Fontaine, Jean-Charles; Gelé, Denis; Goerlach, Ulrich; Juillot, Pierre; Le Bihan, Anne-Catherine; Van Hove, Pierre; Fassi, Farida; Mercier, Damien; Beauceron, Stephanie; Beaupere, Nicolas; Bondu, Olivier; Boudoul, Gaelle; Chasserat, Julien; Chierici, Roberto; Contardo, Didier; Depasse, Pierre; El Mamouni, Houmani; Fay, Jean; Gascon, Susan; Gouzevitch, Maxime; Ille, Bernard; Kurca, Tibor; Lethuillier, Morgan; Mirabito, Laurent; Perries, Stephane; Sgandurra, Louis; Sordini, Viola; Tschudi, Yohann; Verdier, Patrice; Viret, Sébastien; Tsamalaidze, Zviad; Anagnostou, Georgios; Autermann, Christian; Beranek, Sarah; Edelhoff, Matthias; Feld, Lutz; Heracleous, Natalie; Hindrichs, Otto; Jussen, Ruediger; Klein, Katja; Merz, Jennifer; Ostapchuk, Andrey; Perieanu, Adrian; Raupach, Frank; Sammet, Jan; Schael, Stefan; Sprenger, Daniel; Weber, Hendrik; Wittmer, Bruno; Zhukov, Valery; Ata, Metin; Caudron, Julien; Dietz-Laursonn, Erik; Duchardt, Deborah; Erdmann, Martin; Fischer, Robert; Güth, Andreas; Hebbeker, Thomas; Heidemann, Carsten; Hoepfner, Kerstin; Klingebiel, Dennis; Kreuzer, Peter; Merschmeyer, Markus; Meyer, Arnd; Olschewski, Mark; Papacz, Paul; Pieta, Holger; Reithler, Hans; Schmitz, Stefan Antonius; Sonnenschein, Lars; Steggemann, Jan; Teyssier, Daniel; Weber, Martin; Bontenackels, Michael; Cherepanov, Vladimir; Erdogan, Yusuf; Flügge, Günter; Geenen, Heiko; Geisler, Matthias; Haj Ahmad, Wael; Hoehle, Felix; Kargoll, Bastian; Kress, Thomas; Kuessel, Yvonne; Lingemann, Joschka; Nowack, Andreas; Perchalla, Lars; Pooth, Oliver; Sauerland, Philip; Stahl, Achim; Aldaya Martin, Maria; Behr, Joerg; Behrenhoff, Wolf; Behrens, Ulf; Bergholz, Matthias; Bethani, Agni; Borras, Kerstin; Burgmeier, Armin; Cakir, Altan; Calligaris, Luigi; Campbell, Alan; Castro, Elena; Costanza, Francesco; Dammann, Dirk; Diez Pardos, Carmen; Eckerlin, Guenter; Eckstein, Doris; Flucke, Gero; Geiser, Achim; Glushkov, Ivan; Gunnellini, Paolo; Habib, Shiraz; Hauk, Johannes; Hellwig, Gregor; Jung, Hannes; Kasemann, Matthias; Katsas, Panagiotis; Kleinwort, Claus; Kluge, Hannelies; Knutsson, Albert; Krämer, Mira; Krücker, Dirk; Kuznetsova, Ekaterina; Lange, Wolfgang; Lohmann, Wolfgang; Lutz, Benjamin; Mankel, Rainer; Marfin, Ihar; Marienfeld, Markus; Melzer-Pellmann, Isabell-Alissandra; Meyer, Andreas Bernhard; Mnich, Joachim; Mussgiller, Andreas; Naumann-Emme, Sebastian; Novgorodova, Olga; Olzem, Jan; Perrey, Hanno; Petrukhin, Alexey; Pitzl, Daniel; Raspereza, Alexei; Ribeiro Cipriano, Pedro M; Riedl, Caroline; Ron, Elias; Rosin, Michele; Salfeld-Nebgen, Jakob; Schmidt, Ringo; Schoerner-Sadenius, Thomas; Sen, Niladri; Spiridonov, Alexander; Stein, Matthias; Walsh, Roberval; Wissing, Christoph; Blobel, Volker; Draeger, Jula; Enderle, Holger; Erfle, Joachim; Gebbert, Ulla; Görner, Martin; Hermanns, Thomas; Höing, Rebekka Sophie; Kaschube, Kolja; Kaussen, Gordon; Kirschenmann, Henning; Klanner, Robert; Lange, Jörn; Mura, Benedikt; Nowak, Friederike; Peiffer, Thomas; Pietsch, Niklas; Rathjens, Denis; Sander, Christian; Schettler, Hannes; Schleper, Peter; Schlieckau, Eike; Schmidt, Alexander; Schröder, Matthias; Schum, Torben; Seidel, Markus; Sola, Valentina; Stadie, Hartmut; Steinbrück, Georg; Thomsen, Jan; Vanelderen, Lukas; Barth, Christian; Berger, Joram; Böser, Christian; Chwalek, Thorsten; De Boer, Wim; Descroix, Alexis; Dierlamm, Alexander; Feindt, Michael; Guthoff, Moritz; Hackstein, Christoph; Hartmann, Frank; Hauth, Thomas; Heinrich, Michael; Held, Hauke; Hoffmann, Karl-Heinz; Husemann, Ulrich; Katkov, Igor; Komaragiri, Jyothsna Rani; Lobelle Pardo, Patricia; Martschei, Daniel; Mueller, Steffen; Müller, Thomas; Niegel, Martin; Nürnberg, Andreas; Oberst, Oliver; Oehler, Andreas; Ott, Jochen; Quast, Gunter; Rabbertz, Klaus; Ratnikov, Fedor; Ratnikova, Natalia; Röcker, Steffen; Schilling, Frank-Peter; Schott, Gregory; Simonis, Hans-Jürgen; Stober, Fred-Markus Helmut; Troendle, Daniel; Ulrich, Ralf; Wagner-Kuhr, Jeannine; Wayand, Stefan; Weiler, Thomas; Zeise, Manuel; Daskalakis, Georgios; Geralis, Theodoros; Kesisoglou, Stilianos; Kyriakis, Aristotelis; Loukas, Demetrios; Manolakos, Ioannis; Markou, Athanasios; Markou, Christos; Mavrommatis, Charalampos; Ntomari, Eleni; Gouskos, Loukas; Mertzimekis, Theodoros; Panagiotou, Apostolos; Saoulidou, Niki; Evangelou, Ioannis; Foudas, Costas; Kokkas, Panagiotis; Manthos, Nikolaos; Papadopoulos, Ioannis; Patras, Vaios; Bencze, Gyorgy; Hajdu, Csaba; Hidas, Pàl; Horvath, Dezso; Sikler, Ferenc; Veszpremi, Viktor; Vesztergombi, Gyorgy; Beni, Noemi; Czellar, Sandor; Molnar, Jozsef; Palinkas, Jozsef; Szillasi, Zoltan; Karancsi, János; Raics, Peter; Trocsanyi, Zoltan Laszlo; Ujvari, Balazs; Beri, Suman Bala; Bhatnagar, Vipin; Dhingra, Nitish; Gupta, Ruchi; Kaur, Manjit; Mehta, Manuk Zubin; Nishu, Nishu; Saini, Lovedeep Kaur; Sharma, Archana; Singh, Jasbir; Kumar, Ashok; Kumar, Arun; Ahuja, Sudha; Bhardwaj, Ashutosh; Choudhary, Brajesh C; Malhotra, Shivali; Naimuddin, Md; Ranjan, Kirti; Sharma, Varun; Shivpuri, Ram Krishen; Banerjee, Sunanda; Bhattacharya, Satyaki; Dutta, Suchandra; Gomber, Bhawna; Jain, Sandhya; Jain, Shilpi; Khurana, Raman; Sarkar, Subir; Sharan, Manoj; Abdulsalam, Abdulla; Choudhury, Rajani Kant; Dutta, Dipanwita; Kailas, Swaminathan; Kumar, Vineet; Mehta, Pourus; Mohanty, Ajit Kumar; Pant, Lalit Mohan; Shukla, Prashant; Aziz, Tariq; Ganguly, Sanmay; Guchait, Monoranjan; Maity, Manas; Majumder, Gobinda; Mazumdar, Kajari; Mohanty, Gagan Bihari; Parida, Bibhuti; Sudhakar, Katta; Wickramage, Nadeesha; Banerjee, Sudeshna; Dugad, Shashikant; Arfaei, Hessamaddin; Bakhshiansohi, Hamed; Etesami, Seyed Mohsen; Fahim, Ali; Hashemi, Majid; Hesari, Hoda; Jafari, Abideh; Khakzad, Mohsen; Mohammadi Najafabadi, Mojtaba; Paktinat Mehdiabadi, Saeid; Safarzadeh, Batool; Zeinali, Maryam; Abbrescia, Marcello; Barbone, Lucia; Calabria, Cesare; Chhibra, Simranjit Singh; Colaleo, Anna; Creanza, Donato; De Filippis, Nicola; De Palma, Mauro; Fiore, Luigi; Iaselli, Giuseppe; Lusito, Letizia; Maggi, Giorgio; Maggi, Marcello; Marangelli, Bartolomeo; My, Salvatore; Nuzzo, Salvatore; Pacifico, Nicola; Pompili, Alexis; Pugliese, Gabriella; Selvaggi, Giovanna; Silvestris, Lucia; Singh, Gurpreet; Venditti, Rosamaria; Zito, Giuseppe; Abbiendi, Giovanni; Benvenuti, Alberto; Bonacorsi, Daniele; Braibant-Giacomelli, Sylvie; Brigliadori, Luca; Capiluppi, Paolo; Castro, Andrea; Cavallo, Francesca Romana; Cuffiani, Marco; Dallavalle, Gaetano-Marco; Fabbri, Fabrizio; Fanfani, Alessandra; Fasanella, Daniele; Giacomelli, Paolo; Grandi, Claudio; Guiducci, Luigi; Marcellini, Stefano; Masetti, Gianni; Meneghelli, Marco; Montanari, Alessandro; Navarria, Francesco; Odorici, Fabrizio; Perrotta, Andrea; Primavera, Federica; Rossi, Antonio; Rovelli, Tiziano; Siroli, Gian Piero; Travaglini, Riccardo; Albergo, Sebastiano; Cappello, Gigi; Chiorboli, Massimiliano; Costa, Salvatore; Potenza, Renato; Tricomi, Alessia; Tuve, Cristina; Barbagli, Giuseppe; Ciulli, Vitaliano; Civinini, Carlo; D'Alessandro, Raffaello; Focardi, Ettore; Frosali, Simone; Gallo, Elisabetta; Gonzi, Sandro; Meschini, Marco; Paoletti, Simone; Sguazzoni, Giacomo; Tropiano, Antonio; Benussi, Luigi; Bianco, Stefano; Colafranceschi, Stefano; Fabbri, Franco; Piccolo, Davide; Fabbricatore, Pasquale; Musenich, Riccardo; Tosi, Silvano; Benaglia, Andrea; De Guio, Federico; Di Matteo, Leonardo; Fiorendi, Sara; Gennai, Simone; Ghezzi, Alessio; Malvezzi, Sandra; Manzoni, Riccardo Andrea; Martelli, Arabella; Massironi, Andrea; Menasce, Dario; Moroni, Luigi; Paganoni, Marco; Pedrini, Daniele; Ragazzi, Stefano; Redaelli, Nicola; Sala, Silvano; Tabarelli de Fatis, Tommaso; Buontempo, Salvatore; Carrillo Montoya, Camilo Andres; Cavallo, Nicola; De Cosa, Annapaola; Dogangun, Oktay; Fabozzi, Francesco; Iorio, Alberto Orso Maria; Lista, Luca; Meola, Sabino; Merola, Mario; Paolucci, Pierluigi; Azzi, Patrizia; Bacchetta, Nicola; Bellan, Paolo; Bisello, Dario; Branca, Antonio; Carlin, Roberto; Checchia, Paolo; Dorigo, Tommaso; Dosselli, Umberto; Gasparini, Fabrizio; Gasparini, Ugo; Gozzelino, Andrea; Kanishchev, Konstantin; Lacaprara, Stefano; Lazzizzera, Ignazio; Margoni, Martino; Meneguzzo, Anna Teresa; Nespolo, Massimo; Pazzini, Jacopo; Ronchese, Paolo; Simonetto, Franco; Torassa, Ezio; Vanini, Sara; Zotto, Pierluigi; Zumerle, Gianni; Gabusi, Michele; Ratti, Sergio P; Riccardi, Cristina; Torre, Paola; Vitulo, Paolo; Biasini, Maurizio; Bilei, Gian Mario; Fanò, Livio; Lariccia, Paolo; Mantovani, Giancarlo; Menichelli, Mauro; Nappi, Aniello; Romeo, Francesco; Saha, Anirban; Santocchia, Attilio; Spiezia, Aniello; Taroni, Silvia; Azzurri, Paolo; Bagliesi, Giuseppe; Bernardini, Jacopo; Boccali, Tommaso; Broccolo, Giuseppe; Castaldi, Rino; D'Agnolo, Raffaele Tito; Dell'Orso, Roberto; Fiori, Francesco; Foà, Lorenzo; Giassi, Alessandro; Kraan, Aafke; Ligabue, Franco; Lomtadze, Teimuraz; Martini, Luca; Messineo, Alberto; Palla, Fabrizio; Rizzi, Andrea; Serban, Alin Titus; Spagnolo, Paolo; Squillacioti, Paola; Tenchini, Roberto; Tonelli, Guido; Venturi, Andrea; Verdini, Piero Giorgio; Barone, Luciano; Cavallari, Francesca; Del Re, Daniele; Diemoz, Marcella; Fanelli, Cristiano; Grassi, Marco; Longo, Egidio; Meridiani, Paolo; Micheli, Francesco; Nourbakhsh, Shervin; Organtini, Giovanni; Paramatti, Riccardo; Rahatlou, Shahram; Sigamani, Michael; Soffi, Livia; Amapane, Nicola; Arcidiacono, Roberta; Argiro, Stefano; Arneodo, Michele; Biino, Cristina; Cartiglia, Nicolo; Costa, Marco; Demaria, Natale; Mariotti, Chiara; Maselli, Silvia; Migliore, Ernesto; Monaco, Vincenzo; Musich, Marco; Obertino, Maria Margherita; Pastrone, Nadia; Pelliccioni, Mario; Potenza, Alberto; Romero, Alessandra; Ruspa, Marta; Sacchi, Roberto; Solano, Ada; Staiano, Amedeo; Vilela Pereira, Antonio; Belforte, Stefano; Candelise, Vieri; Casarsa, Massimo; Cossutti, Fabio; Della Ricca, Giuseppe; Gobbo, Benigno; Marone, Matteo; Montanino, Damiana; Penzo, Aldo; Schizzi, Andrea; Heo, Seong Gu; Kim, Tae Yeon; Nam, Soon-Kwon; Chang, Sunghyun; Kim, Dong Hee; Kim, Gui Nyun; Kong, Dae Jung; Park, Hyangkyu; Ro, Sang-Ryul; Son, Dong-Chul; Son, Taejin; Kim, Jae Yool; Kim, Zero Jaeho; Song, Sanghyeon; Choi, Suyong; Gyun, Dooyeon; Hong, Byung-Sik; Jo, Mihee; Kim, Hyunchul; Kim, Tae Jeong; Lee, Kyong Sei; Moon, Dong Ho; Park, Sung Keun; Choi, Minkyoo; Kim, Ji Hyun; Park, Chawon; Park, Inkyu; Park, Sangnam; Ryu, Geonmo; Cho, Yongjin; Choi, Young-Il; Choi, Young Kyu; Goh, Junghwan; Kim, Min Suk; Kwon, Eunhyang; Lee, Byounghoon; Lee, Jongseok; Lee, Sungeun; Seo, Hyunkwan; Yu, Intae; Bilinskas, Mykolas Jurgis; Grigelionis, Ignas; Janulis, Mindaugas; Juodagalvis, Andrius; Castilla-Valdez, Heriberto; De La Cruz-Burelo, Eduard; Heredia-de La Cruz, Ivan; Lopez-Fernandez, Ricardo; Magaña Villalba, Ricardo; Martínez-Ortega, Jorge; Sánchez Hernández, Alberto; Villasenor-Cendejas, Luis Manuel; Carrillo Moreno, Salvador; Vazquez Valencia, Fabiola; Salazar Ibarguen, Humberto Antonio; Casimiro Linares, Edgar; Morelos Pineda, Antonio; Reyes-Santos, Marco A; Krofcheck, David; Bell, Alan James; Butler, Philip H; Doesburg, Robert; Reucroft, Steve; Silverwood, Hamish; Ahmad, Muhammad; Ansari, Muhammad Hamid; Asghar, Muhammad Irfan; Hoorani, Hafeez R; Khalid, Shoaib; Khan, Wajid Ali; Khurshid, Taimoor; Qazi, Shamona; Shah, Mehar Ali; Shoaib, Muhammad; Bialkowska, Helena; Boimska, Bozena; Frueboes, Tomasz; Gokieli, Ryszard; Górski, Maciej; Kazana, Malgorzata; Nawrocki, Krzysztof; Romanowska-Rybinska, Katarzyna; Szleper, Michal; Wrochna, Grzegorz; Zalewski, Piotr; Brona, Grzegorz; Bunkowski, Karol; Cwiok, Mikolaj; Dominik, Wojciech; Doroba, Krzysztof; Kalinowski, Artur; Konecki, Marcin; Krolikowski, Jan; Almeida, Nuno; Bargassa, Pedrame; David Tinoco Mendes, Andre; Faccioli, Pietro; Ferreira Parracho, Pedro Guilherme; Gallinaro, Michele; Seixas, Joao; Varela, Joao; Vischia, Pietro; Bunin, Pavel; Gavrilenko, Mikhail; Golutvin, Igor; Karjavin, Vladimir; Konoplyanikov, Viktor; Kozlov, Guennady; Lanev, Alexander; Malakhov, Alexander; Moisenz, Petr; Palichik, Vladimir; Perelygin, Victor; Savina, Maria; Shmatov, Sergey; Shulha, Siarhei; Smirnov, Vitaly; Volodko, Anton; Zarubin, Anatoli; Evstyukhin, Sergey; Golovtsov, Victor; Ivanov, Yury; Kim, Victor; Levchenko, Petr; Murzin, Victor; Oreshkin, Vadim; Smirnov, Igor; Sulimov, Valentin; Uvarov, Lev; Vavilov, Sergey; Vorobyev, Alexey; Vorobyev, Andrey; Andreev, Yuri; Dermenev, Alexander; Gninenko, Sergei; Golubev, Nikolai; Kirsanov, Mikhail; Krasnikov, Nikolai; Matveev, Viktor; Pashenkov, Anatoli; Tlisov, Danila; Toropin, Alexander; Epshteyn, Vladimir; Erofeeva, Maria; Gavrilov, Vladimir; Kossov, Mikhail; Lychkovskaya, Natalia; Popov, Vladimir; Safronov, Grigory; Semenov, Sergey; Stolin, Viatcheslav; Vlasov, Evgueni; Zhokin, Alexander; Belyaev, Andrey; Boos, Edouard; Dubinin, Mikhail; Dudko, Lev; Ershov, Alexander; Gribushin, Andrey; Klyukhin, Vyacheslav; Kodolova, Olga; Lokhtin, Igor; Markina, Anastasia; Obraztsov, Stepan; Perfilov, Maxim; Petrushanko, Sergey; Popov, Andrey; Sarycheva, Ludmila; Savrin, Viktor; Snigirev, Alexander; Andreev, Vladimir; Azarkin, Maksim; Dremin, Igor; Kirakosyan, Martin; Leonidov, Andrey; Mesyats, Gennady; Rusakov, Sergey V; Vinogradov, Alexey; Azhgirey, Igor; Bayshev, Igor; Bitioukov, Sergei; Grishin, Viatcheslav; Kachanov, Vassili; Konstantinov, Dmitri; Krychkine, Victor; Petrov, Vladimir; Ryutin, Roman; Sobol, Andrei; Tourtchanovitch, Leonid; Troshin, Sergey; Tyurin, Nikolay; Uzunian, Andrey; Volkov, Alexey; Adzic, Petar; Djordjevic, Milos; Ekmedzic, Marko; Krpic, Dragomir; Milosevic, Jovan; Aguilar-Benitez, Manuel; Alcaraz Maestre, Juan; Arce, Pedro; Battilana, Carlo; Calvo, Enrique; Cerrada, Marcos; Chamizo Llatas, Maria; Colino, Nicanor; De La Cruz, Begona; Delgado Peris, Antonio; Domínguez Vázquez, Daniel; Fernandez Bedoya, Cristina; Fernández Ramos, Juan Pablo; Ferrando, Antonio; Flix, Jose; Fouz, Maria Cruz; Garcia-Abia, Pablo; Gonzalez Lopez, Oscar; Goy Lopez, Silvia; Hernandez, Jose M; Josa, Maria Isabel; Merino, Gonzalo; Puerta Pelayo, Jesus; Quintario Olmeda, Adrián; Redondo, Ignacio; Romero, Luciano; Santaolalla, Javier; Senghi Soares, Mara; Willmott, Carlos; Albajar, Carmen; Codispoti, Giuseppe; de Trocóniz, Jorge F; Brun, Hugues; Cuevas, Javier; Fernandez Menendez, Javier; Folgueras, Santiago; Gonzalez Caballero, Isidro; Lloret Iglesias, Lara; Piedra Gomez, Jonatan; Brochero Cifuentes, Javier Andres; Cabrillo, Iban Jose; Calderon, Alicia; Chuang, Shan-Huei; Duarte Campderros, Jordi; Felcini, Marta; Fernandez, Marcos; Gomez, Gervasio; Gonzalez Sanchez, Javier; Graziano, Alberto; Jorda, Clara; Lopez Virto, Amparo; Marco, Jesus; Marco, Rafael; Martinez Rivero, Celso; Matorras, Francisco; Munoz Sanchez, Francisca Javiela; Rodrigo, Teresa; Rodríguez-Marrero, Ana Yaiza; Ruiz-Jimeno, Alberto; Scodellaro, Luca; Vila, Ivan; Vilar Cortabitarte, Rocio; Abbaneo, Duccio; Auffray, Etiennette; Auzinger, Georg; Bachtis, Michail; Baillon, Paul; Ball, Austin; Barney, David; Benitez, Jose F; Bernet, Colin; Bianchi, Giovanni; Bloch, Philippe; Bocci, Andrea; Bonato, Alessio; Botta, Cristina; Breuker, Horst; Camporesi, Tiziano; Cerminara, Gianluca; Christiansen, Tim; Coarasa Perez, Jose Antonio; D'Enterria, David; Dabrowski, Anne; De Roeck, Albert; Di Guida, Salvatore; Dobson, Marc; Dupont-Sagorin, Niels; Elliott-Peisert, Anna; Frisch, Benjamin; Funk, Wolfgang; Georgiou, Georgios; Giffels, Manuel; Gigi, Dominique; Gill, Karl; Giordano, Domenico; Girone, Maria; Giunta, Marina; Glege, Frank; Gomez-Reino Garrido, Robert; Govoni, Pietro; Gowdy, Stephen; Guida, Roberto; Hansen, Magnus; Harris, Philip; Hartl, Christian; Harvey, John; Hegner, Benedikt; Hinzmann, Andreas; Innocente, Vincenzo; Janot, Patrick; Kaadze, Ketino; Karavakis, Edward; Kousouris, Konstantinos; Lecoq, Paul; Lee, Yen-Jie; Lenzi, Piergiulio; Lourenco, Carlos; Magini, Nicolo; Maki, Tuula; Malberti, Martina; Malgeri, Luca; Mannelli, Marcello; Masetti, Lorenzo; Meijers, Frans; Mersi, Stefano; Meschi, Emilio; Moser, Roland; Mozer, Matthias Ulrich; Mulders, Martijn; Musella, Pasquale; Nesvold, Erik; Orimoto, Toyoko; Orsini, Luciano; Palencia Cortezon, Enrique; Perez, Emmanuelle; Perrozzi, Luca; Petrilli, Achille; Pfeiffer, Andreas; Pierini, Maurizio; Pimiä, Martti; Piparo, Danilo; Polese, Giovanni; Quertenmont, Loic; Racz, Attila; Reece, William; Rodrigues Antunes, Joao; Rolandi, Gigi; Rovelli, Chiara; Rovere, Marco; Sakulin, Hannes; Santanastasio, Francesco; Schäfer, Christoph; Schwick, Christoph; Segoni, Ilaria; Sekmen, Sezen; Sharma, Archana; Siegrist, Patrice; Silva, Pedro; Simon, Michal; Sphicas, Paraskevas; Spiga, Daniele; Tsirou, Andromachi; Veres, Gabor Istvan; Vlimant, Jean-Roch; Wöhri, Hermine Katharina; Worm, Steven; Zeuner, Wolfram Dietrich; Bertl, Willi; Deiters, Konrad; Erdmann, Wolfram; Gabathuler, Kurt; Horisberger, Roland; Ingram, Quentin; Kaestli, Hans-Christian; König, Stefan; Kotlinski, Danek; Langenegger, Urs; Meier, Frank; Renker, Dieter; Rohe, Tilman; Sibille, Jennifer; Bäni, Lukas; Bortignon, Pierluigi; Buchmann, Marco-Andrea; Casal, Bruno; Chanon, Nicolas; Deisher, Amanda; Dissertori, Günther; Dittmar, Michael; Donegà, Mauro; Dünser, Marc; Eugster, Jürg; Freudenreich, Klaus; Grab, Christoph; Hits, Dmitry; Lecomte, Pierre; Lustermann, Werner; Marini, Andrea Carlo; Martinez Ruiz del Arbol, Pablo; Mohr, Niklas; Moortgat, Filip; Nägeli, Christoph; Nef, Pascal; Nessi-Tedaldi, Francesca; Pandolfi, Francesco; Pape, Luc; Pauss, Felicitas; Peruzzi, Marco; Ronga, Frederic Jean; Rossini, Marco; Sala, Leonardo; Sanchez, Ann - Karin; Starodumov, Andrei; Stieger, Benjamin; Takahashi, Maiko; Tauscher, Ludwig; Thea, Alessandro; Theofilatos, Konstantinos; Treille, Daniel; Urscheler, Christina; Wallny, Rainer; Weber, Hannsjoerg Artur; Wehrli, Lukas; Amsler, Claude; Chiochia, Vincenzo; De Visscher, Simon; Favaro, Carlotta; Ivova Rikova, Mirena; Millan Mejias, Barbara; Otiougova, Polina; Robmann, Peter; Snoek, Hella; Tupputi, Salvatore; Verzetti, Mauro; Chang, Yuan-Hann; Chen, Kuan-Hsin; Kuo, Chia-Ming; Li, Syue-Wei; Lin, Willis; Liu, Zong-Kai; Lu, Yun-Ju; Mekterovic, Darko; Singh, Anil; Volpe, Roberta; Yu, Shin-Shan; Bartalini, Paolo; Chang, Paoti; Chang, You-Hao; Chang, Yu-Wei; Chao, Yuan; Chen, Kai-Feng; Dietz, Charles; Grundler, Ulysses; Hou, George Wei-Shu; Hsiung, Yee; Kao, Kai-Yi; Lei, Yeong-Jyi; Lu, Rong-Shyang; Majumder, Devdatta; Petrakou, Eleni; Shi, Xin; Shiu, Jing-Ge; Tzeng, Yeng-Ming; Wan, Xia; Wang, Minzu; Asavapibhop, Burin; Srimanobhas, Norraphat; Adiguzel, Aytul; Bakirci, Mustafa Numan; Cerci, Salim; Dozen, Candan; Dumanoglu, Isa; Eskut, Eda; Girgis, Semiray; Gokbulut, Gul; Gurpinar, Emine; Hos, Ilknur; Kangal, Evrim Ersin; Karaman, Turker; Karapinar, Guler; Kayis Topaksu, Aysel; Onengut, Gulsen; Ozdemir, Kadri; Ozturk, Sertac; Polatoz, Ayse; Sogut, Kenan; Sunar Cerci, Deniz; Tali, Bayram; Topakli, Huseyin; Vergili, Latife Nukhet; Vergili, Mehmet; Akin, Ilina Vasileva; Aliev, Takhmasib; Bilin, Bugra; Bilmis, Selcuk; Deniz, Muhammed; Gamsizkan, Halil; Guler, Ali Murat; Ocalan, Kadir; Ozpineci, Altug; Serin, Meltem; Sever, Ramazan; Surat, Ugur Emrah; Yalvac, Metin; Yildirim, Eda; Zeyrek, Mehmet; Gülmez, Erhan; Isildak, Bora; Kaya, Mithat; Kaya, Ozlem; Ozkorucuklu, Suat; Sonmez, Nasuf; Cankocak, Kerem; Levchuk, Leonid; Bostock, Francis; Brooke, James John; Clement, Emyr; Cussans, David; Flacher, Henning; Frazier, Robert; Goldstein, Joel; Grimes, Mark; Heath, Greg P; Heath, Helen F; Kreczko, Lukasz; Lucas, Chris; Meng, Zhaoxia; Metson, Simon; Newbold, Dave M; Nirunpong, Kachanon; Poll, Anthony; Senkin, Sergey; Smith, Vincent J; Williams, Thomas; Basso, Lorenzo; Bell, Ken W; Belyaev, Alexander; Brew, Christopher; Brown, Robert M; Cockerill, David JA; Coughlan, John A; Harder, Kristian; Harper, Sam; Jackson, James; Kennedy, Bruce W; Olaiya, Emmanuel; Petyt, David; Radburn-Smith, Benjamin Charles; Shepherd-Themistocleous, Claire; Tomalin, Ian R; Womersley, William John; Bainbridge, Robert; Ball, Gordon; Beuselinck, Raymond; Buchmuller, Oliver; Colling, David; Cripps, Nicholas; Cutajar, Michael; Dauncey, Paul; Davies, Gavin; Della Negra, Michel; Ferguson, William; Fulcher, Jonathan; Futyan, David; Gilbert, Andrew; Guneratne Bryer, Arlo; Hall, Geoffrey; Hatherell, Zoe; Hays, Jonathan; Iles, Gregory; Jarvis, Martyn; Karapostoli, Georgia; Lyons, Louis; Magnan, Anne-Marie; Marrouche, Jad; Mathias, Bryn; Nandi, Robin; Nash, Jordan; Nikitenko, Alexander; Papageorgiou, Anastasios; Pela, Joao; Pesaresi, Mark; Petridis, Konstantinos; Pioppi, Michele; Raymond, David Mark; Rogerson, Samuel; Rose, Andrew; Ryan, Matthew John; Seez, Christopher; Sharp, Peter; Sparrow, Alex; Stoye, Markus; Tapper, Alexander; Vazquez Acosta, Monica; Virdee, Tejinder; Wakefield, Stuart; Wardle, Nicholas; Whyntie, Tom; Chadwick, Matthew; Cole, Joanne; Hobson, Peter R; Khan, Akram; Kyberd, Paul; Leggat, Duncan; Leslie, Dawn; Martin, William; Reid, Ivan; Symonds, Philip; Teodorescu, Liliana; Turner, Mark; Hatakeyama, Kenichi; Liu, Hongxuan; Scarborough, Tara; Charaf, Otman; Henderson, Conor; Rumerio, Paolo; Avetisyan, Aram; Bose, Tulika; Fantasia, Cory; Heister, Arno; St John, Jason; Lawson, Philip; Lazic, Dragoslav; Rohlf, James; Sperka, David; Sulak, Lawrence; Alimena, Juliette; Bhattacharya, Saptaparna; Cutts, David; Demiragli, Zeynep; Ferapontov, Alexey; Heintz, Ulrich; Jabeen, Shabnam; Kukartsev, Gennadiy; Laird, Edward; Landsberg, Greg; Luk, Michael; Narain, Meenakshi; Nguyen, Duong; Segala, Michael; Sinthuprasith, Tutanon; Speer, Thomas; Tsang, Ka Vang; Breedon, Richard; Breto, Guillermo; Calderon De La Barca Sanchez, Manuel; Chauhan, Sushil; Chertok, Maxwell; Conway, John; Conway, Rylan; Cox, Peter Timothy; Dolen, James; Erbacher, Robin; Gardner, Michael; Houtz, Rachel; Ko, Winston; Kopecky, Alexandra; Lander, Richard; Mall, Orpheus; Miceli, Tia; Pellett, Dave; Ricci-Tam, Francesca; Rutherford, Britney; Searle, Matthew; Smith, John; Squires, Michael; Tripathi, Mani; Vasquez Sierra, Ricardo; Yohay, Rachel; Andreev, Valeri; Cline, David; Cousins, Robert; Duris, Joseph; Erhan, Samim; Everaerts, Pieter; Farrell, Chris; Hauser, Jay; Ignatenko, Mikhail; Jarvis, Chad; Plager, Charles; Rakness, Gregory; Schlein, Peter; Traczyk, Piotr; Valuev, Vyacheslav; Weber, Matthias; Babb, John; Clare, Robert; Dinardo, Mauro Emanuele; Ellison, John Anthony; Gary, J William; Giordano, Ferdinando; Hanson, Gail; Jeng, Geng-Yuan; Liu, Hongliang; Long, Owen Rosser; Luthra, Arun; Nguyen, Harold; Paramesvaran, Sudarshan; Sturdy, Jared; Sumowidagdo, Suharyo; Wilken, Rachel; Wimpenny, Stephen; Andrews, Warren; Branson, James G; Cerati, Giuseppe Benedetto; Cittolin, Sergio; Evans, David; Golf, Frank; Holzner, André; Kelley, Ryan; Lebourgeois, Matthew; Letts, James; Macneill, Ian; Mangano, Boris; Padhi, Sanjay; Palmer, Christopher; Petrucciani, Giovanni; Pieri, Marco; Sani, Matteo; Sharma, Vivek; Simon, Sean; Sudano, Elizabeth; Tadel, Matevz; Tu, Yanjun; Vartak, Adish; Wasserbaech, Steven; Würthwein, Frank; Yagil, Avraham; Yoo, Jaehyeok; Barge, Derek; Bellan, Riccardo; Campagnari, Claudio; D'Alfonso, Mariarosaria; Danielson, Thomas; Flowers, Kristen; Geffert, Paul; Incandela, Joe; Justus, Christopher; Kalavase, Puneeth; Koay, Sue Ann; Kovalskyi, Dmytro; Krutelyov, Vyacheslav; Lowette, Steven; Mccoll, Nickolas; Pavlunin, Viktor; Rebassoo, Finn; Ribnik, Jacob; Richman, Jeffrey; Rossin, Roberto; Stuart, David; To, Wing; West, Christopher; Apresyan, Artur; Bornheim, Adolf; Chen, Yi; Di Marco, Emanuele; Duarte, Javier; Gataullin, Marat; Ma, Yousi; Mott, Alexander; Newman, Harvey B; Rogan, Christopher; Spiropulu, Maria; Timciuc, Vladlen; Veverka, Jan; Wilkinson, Richard; Xie, Si; Yang, Yong; Zhu, Ren-Yuan; Akgun, Bora; Azzolini, Virginia; Calamba, Aristotle; Carroll, Ryan; Ferguson, Thomas; Iiyama, Yutaro; Jang, Dong Wook; Liu, Yueh-Feng; Paulini, Manfred; Vogel, Helmut; Vorobiev, Igor; Cumalat, John Perry; Drell, Brian Robert; Ford, William T; Gaz, Alessandro; Luiggi Lopez, Eduardo; Smith, James; Stenson, Kevin; Ulmer, Keith; Wagner, Stephen Robert; Alexander, James; Chatterjee, Avishek; Eggert, Nicholas; Gibbons, Lawrence Kent; Heltsley, Brian; Khukhunaishvili, Aleko; Kreis, Benjamin; Mirman, Nathan; Nicolas Kaufman, Gala; Patterson, Juliet Ritchie; Ryd, Anders; Salvati, Emmanuele; Sun, Werner; Teo, Wee Don; Thom, Julia; Thompson, Joshua; Tucker, Jordan; Vaughan, Jennifer; Weng, Yao; Winstrom, Lucas; Wittich, Peter; Winn, Dave; Abdullin, Salavat; Albrow, Michael; Anderson, Jacob; Bauerdick, Lothar AT; Beretvas, Andrew; Berryhill, Jeffrey; Bhat, Pushpalatha C; Bloch, Ingo; Burkett, Kevin; Butler, Joel Nathan; Chetluru, Vasundhara; Cheung, Harry; Chlebana, Frank; Elvira, Victor Daniel; Fisk, Ian; Freeman, Jim; Gao, Yanyan; Green, Dan; Gutsche, Oliver; Hanlon, Jim; Harris, Robert M; Hirschauer, James; Hooberman, Benjamin; Jindariani, Sergo; Johnson, Marvin; Joshi, Umesh; Kilminster, Benjamin; Klima, Boaz; Kunori, Shuichi; Kwan, Simon; Leonidopoulos, Christos; Linacre, Jacob; Lincoln, Don; Lipton, Ron; Lykken, Joseph; Maeshima, Kaori; Marraffino, John Michael; Maruyama, Sho; Mason, David; McBride, Patricia; Mishra, Kalanand; Mrenna, Stephen; Musienko, Yuri; Newman-Holmes, Catherine; O'Dell, Vivian; Prokofyev, Oleg; Sexton-Kennedy, Elizabeth; Sharma, Seema; Spalding, William J; Spiegel, Leonard; Taylor, Lucas; Tkaczyk, Slawek; Tran, Nhan Viet; Uplegger, Lorenzo; Vaandering, Eric Wayne; Vidal, Richard; Whitmore, Juliana; Wu, Weimin; Yang, Fan; Yumiceva, Francisco; Yun, Jae Chul; Acosta, Darin; Avery, Paul; Bourilkov, Dimitri; Chen, Mingshui; Cheng, Tongguang; Das, Souvik; De Gruttola, Michele; Di Giovanni, Gian Piero; Dobur, Didar; Drozdetskiy, Alexey; Field, Richard D; Fisher, Matthew; Fu, Yu; Furic, Ivan-Kresimir; Gartner, Joseph; Hugon, Justin; Kim, Bockjoo; Konigsberg, Jacobo; Korytov, Andrey; Kropivnitskaya, Anna; Kypreos, Theodore; Low, Jia Fu; Matchev, Konstantin; Milenovic, Predrag; Mitselmakher, Guenakh; Muniz, Lana; Park, Myeonghun; Remington, Ronald; Rinkevicius, Aurelijus; Sellers, Paul; Skhirtladze, Nikoloz; Snowball, Matthew; Yelton, John; Zakaria, Mohammed; Gaultney, Vanessa; Hewamanage, Samantha; Lebolo, Luis Miguel; Linn, Stephan; Markowitz, Pete; Martinez, German; Rodriguez, Jorge Luis; Adams, Todd; Askew, Andrew; Bochenek, Joseph; Chen, Jie; Diamond, Brendan; Gleyzer, Sergei V; Haas, Jeff; Hagopian, Sharon; Hagopian, Vasken; Jenkins, Merrill; Johnson, Kurtis F; Prosper, Harrison; Veeraraghavan, Venkatesh; Weinberg, Marc; Baarmand, Marc M; Dorney, Brian; Hohlmann, Marcus; Kalakhety, Himali; Vodopiyanov, Igor; Adams, Mark Raymond; Anghel, Ioana Maria; Apanasevich, Leonard; Bai, Yuting; Bazterra, Victor Eduardo; Betts, Russell Richard; Bucinskaite, Inga; Callner, Jeremy; Cavanaugh, Richard; Evdokimov, Olga; Gauthier, Lucie; Gerber, Cecilia Elena; Hofman, David Jonathan; Khalatyan, Samvel; Lacroix, Florent; Malek, Magdalena; O'Brien, Christine; Silkworth, Christopher; Strom, Derek; Turner, Paul; Varelas, Nikos; Akgun, Ugur; Albayrak, Elif Asli; Bilki, Burak; Clarida, Warren; Duru, Firdevs; Merlo, Jean-Pierre; Mermerkaya, Hamit; Mestvirishvili, Alexi; Moeller, Anthony; Nachtman, Jane; Newsom, Charles Ray; Norbeck, Edwin; Onel, Yasar; Ozok, Ferhat; Sen, Sercan; Tan, Ping; Tiras, Emrah; Wetzel, James; Yetkin, Taylan; Yi, Kai; Barnett, Bruce Arnold; Blumenfeld, Barry; Bolognesi, Sara; Fehling, David; Giurgiu, Gavril; Gritsan, Andrei; Guo, Zijin; Hu, Guofan; Maksimovic, Petar; Rappoccio, Salvatore; Swartz, Morris; Whitbeck, Andrew; Baringer, Philip; Bean, Alice; Benelli, Gabriele; Kenny Iii, Raymond Patrick; Murray, Michael; Noonan, Daniel; Sanders, Stephen; Stringer, Robert; Tinti, Gemma; Wood, Jeffrey Scott; Zhukova, Victoria; Barfuss, Anne-Fleur; Bolton, Tim; Chakaberia, Irakli; Ivanov, Andrew; Khalil, Sadia; Makouski, Mikhail; Maravin, Yurii; Shrestha, Shruti; Svintradze, Irakli; Gronberg, Jeffrey; Lange, David; Wright, Douglas; Baden, Drew; Boutemeur, Madjid; Calvert, Brian; Eno, Sarah Catherine; Gomez, Jaime; Hadley, Nicholas John; Kellogg, Richard G; Kirn, Malina; Kolberg, Ted; Lu, Ying; Marionneau, Matthieu; Mignerey, Alice; Pedro, Kevin; Peterman, Alison; Skuja, Andris; Temple, Jeffrey; Tonjes, Marguerite; Tonwar, Suresh C; Twedt, Elizabeth; Apyan, Aram; Bauer, Gerry; Bendavid, Joshua; Busza, Wit; Butz, Erik; Cali, Ivan Amos; Chan, Matthew; Dutta, Valentina; Gomez Ceballos, Guillelmo; Goncharov, Maxim; Hahn, Kristan Allan; Kim, Yongsun; Klute, Markus; Krajczar, Krisztian; Luckey, Paul David; Ma, Teng; Nahn, Steve; Paus, Christoph; Ralph, Duncan; Roland, Christof; Roland, Gunther; Rudolph, Matthew; Stephans, George; Stöckli, Fabian; Sumorok, Konstanty; Sung, Kevin; Velicanu, Dragos; Wenger, Edward Allen; Wolf, Roger; Wyslouch, Bolek; Yang, Mingming; Yilmaz, Yetkin; Yoon, Sungho; Zanetti, Marco; Cooper, Seth; Dahmes, Bryan; De Benedetti, Abraham; Franzoni, Giovanni; Gude, Alexander; Kao, Shih-Chuan; Klapoetke, Kevin; Kubota, Yuichi; Mans, Jeremy; Pastika, Nathaniel; Rusack, Roger; Sasseville, Michael; Singovsky, Alexander; Tambe, Norbert; Turkewitz, Jared; Cremaldi, Lucien Marcus; Kroeger, Rob; Perera, Lalith; Rahmat, Rahmat; Sanders, David A; Avdeeva, Ekaterina; Bloom, Kenneth; Bose, Suvadeep; Butt, Jamila; Claes, Daniel R; Dominguez, Aaron; Eads, Michael; Keller, Jason; Kravchenko, Ilya; Lazo-Flores, Jose; Malbouisson, Helena; Malik, Sudhir; Snow, Gregory R; Godshalk, Andrew; Iashvili, Ia; Jain, Supriya; Kharchilava, Avto; Kumar, Ashish; Alverson, George; Barberis, Emanuela; Baumgartel, Darin; Chasco, Matthew; Haley, Joseph; Nash, David; Trocino, Daniele; Wood, Darien; Zhang, Jinzhong; Anastassov, Anton; Kubik, Andrew; Mucia, Nicholas; Odell, Nathaniel; Ofierzynski, Radoslaw Adrian; Pollack, Brian; Pozdnyakov, Andrey; Schmitt, Michael Henry; Stoynev, Stoyan; Velasco, Mayda; Won, Steven; Antonelli, Louis; Berry, Douglas; Brinkerhoff, Andrew; Chan, Kwok Ming; Hildreth, Michael; Jessop, Colin; Karmgard, Daniel John; Kolb, Jeff; Lannon, Kevin; Luo, Wuming; Lynch, Sean; Marinelli, Nancy; Morse, David Michael; Pearson, Tessa; Planer, Michael; Ruchti, Randy; Slaunwhite, Jason; Valls, Nil; Wayne, Mitchell; Wolf, Matthias; Bylsma, Ben; Durkin, Lloyd Stanley; Hill, Christopher; Hughes, Richard; Kotov, Khristian; Ling, Ta-Yung; Puigh, Darren; Rodenburg, Marissa; Vuosalo, Carl; Williams, Grayson; Winer, Brian L; Adam, Nadia; Berry, Edmund; Elmer, Peter; Gerbaudo, Davide; Halyo, Valerie; Hebda, Philip; Hegeman, Jeroen; Hunt, Adam; Jindal, Pratima; Lopes Pegna, David; Lujan, Paul; Marlow, Daniel; Medvedeva, Tatiana; Mooney, Michael; Olsen, James; Piroué, Pierre; Quan, Xiaohang; Raval, Amita; Safdi, Ben; Saka, Halil; Stickland, David; Tully, Christopher; Werner, Jeremy Scott; Zuranski, Andrzej; Brownson, Eric; Lopez, Angel; Mendez, Hector; Ramirez Vargas, Juan Eduardo; Alagoz, Enver; Barnes, Virgil E; Benedetti, Daniele; Bolla, Gino; Bortoletto, Daniela; De Mattia, Marco; Everett, Adam; Hu, Zhen; Jones, Matthew; Koybasi, Ozhan; Kress, Matthew; Laasanen, Alvin T; Leonardo, Nuno; Maroussov, Vassili; Merkel, Petra; Miller, David Harry; Neumeister, Norbert; Shipsey, Ian; Silvers, David; Svyatkovskiy, Alexey; Vidal Marono, Miguel; Yoo, Hwi Dong; Zablocki, Jakub; Zheng, Yu; Guragain, Samir; Parashar, Neeti; Adair, Antony; Boulahouache, Chaouki; Ecklund, Karl Matthew; Geurts, Frank JM; Li, Wei; Padley, Brian Paul; Redjimi, Radia; Roberts, Jay; Zabel, James; Betchart, Burton; Bodek, Arie; Chung, Yeon Sei; Covarelli, Roberto; de Barbaro, Pawel; Demina, Regina; Eshaq, Yossof; Ferbel, Thomas; Garcia-Bellido, Aran; Goldenzweig, Pablo; Han, Jiyeon; Harel, Amnon; Miner, Daniel Carl; Vishnevskiy, Dmitry; Zielinski, Marek; Bhatti, Anwar; Ciesielski, Robert; Demortier, Luc; Goulianos, Konstantin; Lungu, Gheorghe; Malik, Sarah; Mesropian, Christina; Arora, Sanjay; Barker, Anthony; Chou, John Paul; Contreras-Campana, Christian; Contreras-Campana, Emmanuel; Duggan, Daniel; Ferencek, Dinko; Gershtein, Yuri; Gray, Richard; Halkiadakis, Eva; Hidas, Dean; Lath, Amitabh; Panwalkar, Shruti; Park, Michael; Patel, Rishi; Rekovic, Vladimir; Robles, Jorge; Rose, Keith; Salur, Sevil; Schnetzer, Steve; Seitz, Claudia; Somalwar, Sunil; Stone, Robert; Thomas, Scott; Cerizza, Giordano; Hollingsworth, Matthew; Spanier, Stefan; Yang, Zong-Chang; York, Andrew; Eusebi, Ricardo; Flanagan, Will; Gilmore, Jason; Kamon, Teruki; Khotilovich, Vadim; Montalvo, Roy; Osipenkov, Ilya; Pakhotin, Yuriy; Perloff, Alexx; Roe, Jeffrey; Safonov, Alexei; Sakuma, Tai; Sengupta, Sinjini; Suarez, Indara; Tatarinov, Aysen; Toback, David; Akchurin, Nural; Damgov, Jordan; Dragoiu, Cosmin; Dudero, Phillip Russell; Jeong, Chiyoung; Kovitanggoon, Kittikul; Lee, Sung Won; Libeiro, Terence; Roh, Youn; Volobouev, Igor; Appelt, Eric; Delannoy, Andrés G; Florez, Carlos; Greene, Senta; Gurrola, Alfredo; Johns, Willard; Kurt, Pelin; Maguire, Charles; Melo, Andrew; Sharma, Monika; Sheldon, Paul; Snook, Benjamin; Tuo, Shengquan; Velkovska, Julia; Arenton, Michael Wayne; Balazs, Michael; Boutle, Sarah; Cox, Bradley; Francis, Brian; Goodell, Joseph; Hirosky, Robert; Ledovskoy, Alexander; Lin, Chuanzhe; Neu, Christopher; Wood, John; Gollapinni, Sowjanya; Harr, Robert; Karchin, Paul Edmund; Kottachchi Kankanamge Don, Chamath; Lamichhane, Pramod; Sakharov, Alexandre; Anderson, Michael; Belknap, Donald; Borrello, Laura; Carlsmith, Duncan; Cepeda, Maria; Dasu, Sridhara; Friis, Evan; Gray, Lindsey; Grogg, Kira Suzanne; Grothe, Monika; Hall-Wilton, Richard; Herndon, Matthew; Hervé, Alain; Klabbers, Pamela; Klukas, Jeffrey; Lanaro, Armando; Lazaridis, Christos; Leonard, Jessica; Loveless, Richard; Mohapatra, Ajit; Ojalvo, Isabel; Palmonari, Francesco; Pierro, Giuseppe Antonio; Ross, Ian; Savin, Alexander; Smith, Wesley H; Swanson, Joshua

    2013-01-10

    A search for supersymmetry in final states with jets and missing transverse energy is performed in pp collisions at a centre-of-mass energy of $sqrt{s}$ = 7 TeV. The data sample corresponds to an integrated luminosity of 4.98 inverse femtobarns collected by the CMS experiment at the LHC. In this search, a dimensionless kinematic variable, alphaT, is used as the main discriminator between events with genuine and misreconstructed missing transverse energy. The search is performed in a signal region that is binned in the scalar sum of the transverse energy of jets and the number of jets identified as originating from a bottom quark. No excess of events over the standard model expectation is found. Exclusion limits are set in the parameter space of the constrained minimal supersymmetric extension of the standard model, and also in simplified models, with a special emphasis on compressed spectra and third-generation scenarios.

  16. A general approach to search for supersymmetry at the LHC by combining signal enhanced kinematic regions using the ATLAS detector

    CERN Document Server

    Schneider, Basil; Weber, Michele

    The Standard Model of particle physics is a very successful theory, but it cannot describe e.g. gravity or explain the hierarchy problem. Supersymmetry is a proposed extension to the Standard Model that would solve some of its shortcomings by introducing a relation between fermions and bosons through the existence of a supersymmetric partner to every particle in the Standard Model. Since it is a broken symmetry, supersymmetric particles are heavier than their Standard Model counterparts. No supersymmetric particle has been observed to date. The ATLAS experiment at the Large Hadron Collider is a multi-purpose detector to measure parameters in the Standard Model and conduct searches for new particles. Searching for supersymmetric particles is one of the main goals of the experiment. In 2012, 20.3~fb$^{-1}$ of data at a centre-of-mass energy of $\\sqrt{s}$ = 8 TeV was collected by ATLAS. In this thesis, I analyzed the ATLAS data and developed a novel statistical approach that bins a signal enhanced region in pha...

  17. Search and Classification Using Multiple Autonomous Vehicles Decision-Making and Sensor Management

    CERN Document Server

    Wang, Yue

    2012-01-01

    Search and Classification Using Multiple Autonomous Vehicles provides a comprehensive study of decision-making strategies for domain search and object classification using multiple autonomous vehicles (MAV) under both deterministic and probabilistic frameworks. It serves as a first discussion of the problem of effective resource allocation using MAV with sensing limitations, i.e., for search and classification missions over large-scale domains, or when there are far more objects to be found and classified than there are autonomous vehicles available. Under such scenarios, search and classification compete for limited sensing resources. This is because search requires vehicle mobility while classification restricts the vehicles to the vicinity of any objects found. The authors develop decision-making strategies to choose between these competing tasks and vehicle-motion-control laws to achieve the proposed management scheme. Deterministic Lyapunov-based, probabilistic Bayesian-based, and risk-based decision-mak...

  18. A methodological survey identified eight proposed frameworks for the adaptation of health related guidelines.

    Science.gov (United States)

    Darzi, Andrea; Abou-Jaoude, Elias A; Agarwal, Arnav; Lakis, Chantal; Wiercioch, Wojtek; Santesso, Nancy; Brax, Hneine; El-Jardali, Fadi; Schünemann, Holger J; Akl, Elie A

    2017-06-01

    Our objective was to identify and describe published frameworks for adaptation of clinical, public health, and health services guidelines. We included reports describing methods of adaptation of guidelines in sufficient detail to allow its reproducibility. We searched Medline and EMBASE databases. We also searched personal files, as well manuals and handbooks of organizations and professional societies that proposed methods of adaptation and adoption of guidelines. We followed standard systematic review methodology. Our search captured 12,021 citations, out of which we identified eight proposed methods of guidelines adaptation: ADAPTE, Adapted ADAPTE, Alberta Ambassador Program adaptation phase, GRADE-ADOLOPMENT, MAGIC, RAPADAPTE, Royal College of Nursing (RCN), and Systematic Guideline Review (SGR). The ADAPTE framework consists of a 24-step process to adapt guidelines to a local context taking into consideration the needs, priorities, legislation, policies, and resources. The Alexandria Center for Evidence-Based Clinical Practice Guidelines updated one of ADAPTE's tools, modified three tools, and added three new ones. In addition, they proposed optionally using three other tools. The Alberta Ambassador Program adaptation phase consists of 11 steps and focused on adapting good-quality guidelines for nonspecific low back pain into local context. GRADE-ADOLOPMENT is an eight-step process based on the GRADE Working Group's Evidence to Decision frameworks and applied in 22 guidelines in the context of national guideline development program. The MAGIC research program developed a five-step adaptation process, informed by ADAPTE and the GRADE approach in the context of adapting thrombosis guidelines. The RAPADAPTE framework consists of 12 steps based on ADAPTE and using synthesized evidence databases, retrospectively derived from the experience of producing a high-quality guideline for the treatment of breast cancer with limited resources in Costa Rica. The RCN outlines

  19. Optimally setting up directed searches for continuous gravitational waves in Advanced LIGO O1 data

    Science.gov (United States)

    Ming, Jing; Papa, Maria Alessandra; Krishnan, Badri; Prix, Reinhard; Beer, Christian; Zhu, Sylvia J.; Eggenstein, Heinz-Bernd; Bock, Oliver; Machenschalk, Bernd

    2018-02-01

    In this paper we design a search for continuous gravitational waves from three supernova remnants: Vela Jr., Cassiopeia A (Cas A) and G347.3. These systems might harbor rapidly rotating neutron stars emitting quasiperiodic gravitational radiation detectable by the advanced LIGO detectors. Our search is designed to use the volunteer computing project Einstein@Home for a few months and assumes the sensitivity and duty cycles of the advanced LIGO detectors during their first science run. For all three supernova remnants, the sky positions of their central compact objects are well known but the frequency and spin-down rates of the neutron stars are unknown which makes the searches computationally limited. In a previous paper we have proposed a general framework for deciding on what target we should spend computational resources and in what proportion, what frequency and spin-down ranges we should search for every target, and with what search setup. Here we further expand this framework and apply it to design a search directed at detecting continuous gravitational wave signals from the most promising three supernova remnants identified as such in the previous work. Our optimization procedure yields broad frequency and spin-down searches for all three objects, at an unprecedented level of sensitivity: The smallest detectable gravitational wave strain h0 for Cas A is expected to be 2 times smaller than the most sensitive upper limits published to date, and our proposed search, which was set up and ran on the volunteer computing project Einstein@Home, covers a much larger frequency range.

  20. Inside the small-scale composting of kitchen and garden wastes: Thermal performance and stratification effect in vertical compost bins.

    Science.gov (United States)

    Arrigoni, Juan Pablo; Paladino, Gabriela; Garibaldi, Lucas Alejandro; Laos, Francisca

    2018-06-01

    Decentralized composting has been proposed as a best available practice, with a highly positive impact on municipal solid wastes management plans. However, in cold climates, decentralized small-scale composting performance to reach thermophilic temperatures (required for the product sanitization) could be poor, due to a lack of critical mass to retain heat. In addition, in these systems the composting process is usually disturbed when new portions of fresh organic waste are combined with previous batches. This causes modifications in the well-known composting evolution pattern. The objective of this work was to improve the understanding of these technical aspects through a real-scale decentralized composting experience carried out under cold climate conditions, in order to assess sanitization performance and to study the effects of fresh feedstock additions in the process evolution. Kitchen and garden organic wastes were composted in 500 L-static compost bins (without turning) for 244 days under cold climate conditions (Bariloche, NW Patagonia, Argentina), using pine wood shavings in a ratio of 1.5:1 v: v (waste: bulking agent). Temperature profile, stability indicators (microbial activity, carbon and nitrogen contents and ratio) and other variables (pH and electrical conductivity), were monitored throughout the experience. Our results indicate that small-scale composting (average generation rate of 7 kg d -1 ) is viable under cold weather conditions, since thermophilic sanitization temperatures (> 55 °C) were maintained for 3 consecutive days in most of the composting mass, according to available USEPA regulations commonly used as a reference for pathogens control in sewage sludge. On the other hand, stability indicators showed a differentiated organic matter degradation process along the compost bins height. Particularly, in the bottommost composting mix layer the process took a longer period to achieve compost stability than the upper layers, suggesting

  1. Methodology used for the determination of physical and mechanical properties of crushed coal and new criteria for the selection of calculating parameters according to which coal bins in thermal power plants are dimensioned

    Energy Technology Data Exchange (ETDEWEB)

    Obradovic, R. [Mining Institute Belgrade, Belgrade (Yugoslavia)

    1997-07-01

    In order to acquire the data necessary for design engineering of coal bins in thermal power plants (TPP), an enhanced research method has been adopted, along with new criteria for the interpretation of the results obtained in the course of crushed coal testing, considering the shearing strength values and the expected elastic deformations of bin walls. The investigations presented in this paper have been carried out in the Thermal Power Plant - Nikola Tesla-B, (TPPNT) in Obrenovac, Yugoslavia. 6 refs., 1 tab.

  2. A 222 energy bins response matrix for a "6Lil scintillator Bss system

    International Nuclear Information System (INIS)

    Lacerda, M. A. S.; Vega C, H. R.; Mendez V, R.; Lorente F, A.; Ibanez F, S.; Gallego D, E.

    2016-10-01

    A new response matrix was calculated for a Bonner Sphere Spectrometer (Bss) with a "6Lil(Eu) scintillator. We utilized the Monte Carlo N-particle radiation transport code MCNPX, version 2.7.0, with Endf/B-VII.0 nuclear data library to calculate the responses for 6 spheres and the bare detector, for energies varying from 9.441 E(-10) MeV to 105.9 MeV, with 20 equal-log(E)-width bins per energy decade, totalizing 222 energy groups. A Bss, like the modeled in this work, was utilized to measure the neutron spectrum generated by the "2"4"1AmBe source of the Universidad Politecnica de Madrid. From the count rates obtained with this Bss system we unfolded neutron spectrum utilizing the BUNKIUT code for 31 energy bins (UTA-4 response matrix) and the MAXED code with the new calculated response functions. We compared spectra obtained with these Bss system / unfold codes with that obtained from measurements performed with a Bss system constituted of 12 spheres with a spherical "3He Sp-9 counter (Centronic Ltd., UK) and MAXED code with the system-specific response functions (Bss-CIEMAT). A relatively good agreement was observed between our response matrix and that calculated by other authors. In general, we observed an improvement in the agreement as the energy increases. However, higher discrepancies were observed for energies close to 1-E(-8) MeV and, mainly, for energies above 20 MeV. These discrepancies were mainly attributed to the differences in cross-section libraries employed. The ambient dose equivalent (H (10)) calculated with the "6Lil-MAXED showed a good agreement with values measured with the neutron area monitor Bert hold Lb 6411 and within 12% the value obtained with another Bss system (Bss-CIEMAT). The response matrix calculated in this work can be utilized together with the MAXED code to generate neutron spectra with a good energy resolution up to 20 MeV. Some additional tests are being done to validate this response matrix and improve the results for energies

  3. Understanding integrated care: a comprehensive conceptual framework based on the integrative functions of primary care.

    Science.gov (United States)

    Valentijn, Pim P; Schepman, Sanneke M; Opheij, Wilfrid; Bruijnzeels, Marc A

    2013-01-01

    Primary care has a central role in integrating care within a health system. However, conceptual ambiguity regarding integrated care hampers a systematic understanding. This paper proposes a conceptual framework that combines the concepts of primary care and integrated care, in order to understand the complexity of integrated care. The search method involved a combination of electronic database searches, hand searches of reference lists (snowball method) and contacting researchers in the field. The process of synthesizing the literature was iterative, to relate the concepts of primary care and integrated care. First, we identified the general principles of primary care and integrated care. Second, we connected the dimensions of integrated care and the principles of primary care. Finally, to improve content validity we held several meetings with researchers in the field to develop and refine our conceptual framework. The conceptual framework combines the functions of primary care with the dimensions of integrated care. Person-focused and population-based care serve as guiding principles for achieving integration across the care continuum. Integration plays complementary roles on the micro (clinical integration), meso (professional and organisational integration) and macro (system integration) level. Functional and normative integration ensure connectivity between the levels. The presented conceptual framework is a first step to achieve a better understanding of the inter-relationships among the dimensions of integrated care from a primary care perspective.

  4. PcapDB: Search Optimized Packet Capture, Version 0.1.0.0

    Energy Technology Data Exchange (ETDEWEB)

    2016-11-04

    PcapDB is a packet capture system designed to optimize the captured data for fast search in the typical (network incident response) use case. The technology involved in this software has been submitted via the IDEAS system and has been filed as a provisional patent. It includes the following primary components: capture: The capture component utilizes existing capture libraries to retrieve packets from network interfaces. Once retrieved the packets are passed to additional threads for sorting into flows and indexing. The sorted flows and indexes are passed to other threads so that they can be written to disk. These components are written in the C programming language. search: The search components provide a means to find relevant flows and the associated packets. A search query is parsed and represented as a search tree. Various search commands, written in C, are then used resolve this tree into a set of search results. The tree generation and search execution management components are written in python. interface: The PcapDB web interface is written in Python on the Django framework. It provides a series of pages, API's, and asynchronous tasks that allow the user to manage the capture system, perform searches, and retrieve results. Web page components are written in HTML,CSS and Javascript.

  5. Hyperentanglement concentration for polarization-spatial-time-bin hyperentangled photon systems with linear optics

    Science.gov (United States)

    Wang, Hong; Ren, Bao-Cang; Alzahrani, Faris; Hobiny, Aatef; Deng, Fu-Guo

    2017-10-01

    Hyperentanglement has significant applications in quantum information processing. Here we present an efficient hyperentanglement concentration protocol (hyper-ECP) for partially hyperentangled Bell states simultaneously entangled in polarization, spatial-mode and time-bin degrees of freedom (DOFs) with the parameter-splitting method, where the parameters of the partially hyperentangled Bell states are known to the remote parties. In this hyper-ECP, only one remote party is required to perform some local operations on the three DOFs of a photon, only the linear optical elements are considered, and the success probability can achieve the maximal value. Our hyper-ECP can be easily generalized to concentrate the N-photon partially hyperentangled Greenberger-Horne-Zeilinger states with known parameters, where the multiple DOFs have largely improved the channel capacity of long-distance quantum communication. All of these make our hyper-ECP more practical and useful in high-capacity long-distance quantum communication.

  6. Assessing the Spread and Uptake of a Framework for Introducing and Evaluating Advanced Practice Nursing Roles.

    Science.gov (United States)

    Boyko, Jennifer A; Carter, Nancy; Bryant-Lukosius, Denise

    2016-08-01

    Health system researchers must ensure that the products of their work meet the needs of various stakeholder groups (e.g., patients, practitioners, and policy makers). Evidence-based frameworks can support the uptake and spread of research evidence; however, their existence as knowledge translation tools does not ensure their uptake and it is difficult to ascertain their spread into research, practice, and policy using existing methods. The purpose of this article is to report results of a study on the spread and uptake of an evidence-based framework (i.e., the participatory, evidence-based, patient-focused process for advanced practice nursing [PEPPA] framework) into research, practice, and policies relevant to the introduction and evaluation of advanced practice nursing roles. We also reflect on the utility of using a modified citation methodology to evaluate knowledge translation efforts. We searched four databases for literature published between 2004 and 2014 citing the original paper in which the PEPPA framework was published, and carried out an Internet search for grey literature using keywords. Relevant data were extracted from sources and organized using NVivo software. We analysed results descriptively. Our search yielded 164 unique sources of which 69.5% were from published literature and the majority (83.4%) of these were published in nursing journals. Most frequently (71.5%), the framework was used by researchers and students in research studies. A smaller number of citations (11.3%) reflected use of the PEPPA framework in practice settings with a focus on role development, implementation, evaluation, or a combination of these. This study demonstrates that the PEPPA framework has been used to varying degrees as intended, and provides guidance on how to evaluate the spread and uptake of research outputs (e.g., theoretical frameworks). Further research is needed about ways to determine whether evidence-informed research tools such as frameworks have been

  7. Genetic Local Search for Optimum Multiuser Detection Problem in DS-CDMA Systems

    Science.gov (United States)

    Wang, Shaowei; Ji, Xiaoyong

    Optimum multiuser detection (OMD) in direct-sequence code-division multiple access (DS-CDMA) systems is an NP-complete problem. In this paper, we present a genetic local search algorithm, which consists of an evolution strategy framework and a local improvement procedure. The evolution strategy searches the space of feasible, locally optimal solutions only. A fast iterated local search algorithm, which employs the proprietary characteristics of the OMD problem, produces local optima with great efficiency. Computer simulations show the bit error rate (BER) performance of the GLS outperforms other multiuser detectors in all cases discussed. The computation time is polynomial complexity in the number of users.

  8. A Competitive and Experiential Assignment in Search Engine Optimization Strategy

    Science.gov (United States)

    Clarke, Theresa B.; Clarke, Irvine, III

    2014-01-01

    Despite an increase in ad spending and demand for employees with expertise in search engine optimization (SEO), methods for teaching this important marketing strategy have received little coverage in the literature. Using Bloom's cognitive goals hierarchy as a framework, this experiential assignment provides a process for educators who may be new…

  9. Introducing PALETTE: an iterative method for conducting a literature search for a review in palliative care.

    Science.gov (United States)

    Zwakman, Marieke; Verberne, Lisa M; Kars, Marijke C; Hooft, Lotty; van Delden, Johannes J M; Spijker, René

    2018-06-02

    In the rapidly developing specialty of palliative care, literature reviews have become increasingly important to inform and improve the field. When applying widely used methods for literature reviews developed for intervention studies onto palliative care, challenges are encountered such as the heterogeneity of palliative care in practice (wide range of domains in patient characteristics, stages of illness and stakeholders), the explorative character of review questions, and the poorly defined keywords and concepts. To overcome the challenges and to provide guidance for researchers to conduct a literature search for a review in palliative care, Palliative cAre Literature rEview iTeraTive mEthod (PALLETE), a pragmatic framework, was developed. We assessed PALETTE with a detailed description. PALETTE consists of four phases; developing the review question, building the search strategy, validating the search strategy and performing the search. The framework incorporates different information retrieval techniques: contacting experts, pearl growing, citation tracking and Boolean searching in a transparent way to maximize the retrieval of literature relevant to the topic of interest. The different components and techniques are repeated until no new articles are qualified for inclusion. The phases within PALETTE are interconnected by a recurrent process of validation on 'golden bullets' (articles that undoubtedly should be part of the review), citation tracking and concept terminology reflecting the review question. To give insight in the value of PALETTE, we compared PALETTE with the recommended search method for reviews of intervention studies. By using PALETTE on two palliative care literature reviews, we were able to improve our review questions and search strategies. Moreover, in comparison with the recommended search for intervention reviews, the number of articles needed to be screened was decreased whereas more relevant articles were retrieved. Overall, PALETTE

  10. Prospects for dark matter searches in the pMSSM

    International Nuclear Information System (INIS)

    Roszkowski, Leszek; Sessolo, Enrico Maria; Williams, Andrew J.

    2015-01-01

    We investigate the prospects for detection of neutralino dark matter in the 19-parameter phenomenological MSSM (pMSSM). We explore very wide ranges of the pMSSM parameters but pay particular attention to the higgsino-like neutralino at the ∼1 TeV scale, which has been shown to be a well motivated solution in many constrained supersymmetric models, as well as to a wino-dominated solution with the mass in the range of 2–3 TeV. After summarising the present bounds on the parameter space from direct and indirect detection experiments, we focus on prospects for detection of the Cherenkov Telescope Array (CTA). To this end, we derive a realistic assessment of the sensitivity of CTA to photon fluxes from dark matter annihilation by means of a binned likelihood analysis for the Einasto and Navarro-Frenk-White halo profiles. We use the most up to date instrument response functions and background simulation model provided by the CTA Collaboration. We find that, with 500 hours of observation, under the Einasto profile CTA is bound to exclude at the 95% C.L. almost all of the ∼1 TeV higgsino region of the pMSSM, effectively closing the window for heavy supersymmetric dark matter in many realistic models. CTA will be able to probe the vast majority of cases corresponding to a spin-independent scattering cross section below the reach of 1-tonne underground detector searches for dark matter, in fact even well below the irreducible neutrino background for direct detection. On the other hand, many points lying beyond the sensitivity of CTA will be within the reach of 1-tonne detectors, and some within collider reach. Altogether, CTA will provide a highly sensitive way of searching for dark matter that will be partially overlapping and partially complementary with 1-tonne detector and collider searches, thus being instrumental to effectively explore the nearly full parameter space of the pMSSM.

  11. Content Based Retrieval Database Management System with Support for Similarity Searching and Query Refinement

    National Research Council Canada - National Science Library

    Ortega-Binderberger, Michael

    2002-01-01

    ... as a critical area of research. This thesis explores how to enhance database systems with content based search over arbitrary abstract data types in a similarity based framework with query refinement...

  12. OpenSearch technology for geospatial resources discovery

    Science.gov (United States)

    Papeschi, Fabrizio; Enrico, Boldrini; Mazzetti, Paolo

    2010-05-01

    set of services for discovery, access, and processing of geospatial resources in a SOA framework. GI-cat is a distributed CSW framework implementation developed by the ESSI Lab of the Italian National Research Council (CNR-IMAA) and the University of Florence. It provides brokering and mediation functionalities towards heterogeneous resources and inventories, exposing several standard interfaces for query distribution. This work focuses on a new GI-cat interface which allows the catalog to be queried according to the OpenSearch syntax specification, thus filling the gap between the SOA architectural design of the CSW and the Web 2.0. At the moment, there is no OGC standard specification about this topic, but an official change request has been proposed in order to enable the OGC catalogues to support OpenSearch queries. In this change request, an OpenSearch extension is proposed providing a standard mechanism to query a resource based on temporal and geographic extents. Two new catalog operations are also proposed, in order to publish a suitable OpenSearch interface. This extended interface is implemented by the modular GI-cat architecture adding a new profiling module called "OpenSearch profiler". Since GI-cat also acts as a clearinghouse catalog, another component called "OpenSearch accessor" is added in order to access OpenSearch compliant services. An important role in the GI-cat extension, is played by the adopted mapping strategy. Two different kind of mappings are required: query, and response elements mapping. Query mapping is provided in order to fit the simple OpenSearch query syntax to the complex CSW query expressed by the OGC Filter syntax. GI-cat internal data model is based on the ISO-19115 profile, that is more complex than the simple XML syndication formats, such as RSS 2.0 and Atom 1.0, suggested by OpenSearch. Once response elements are available, in order to be presented, they need to be translated from the GI-cat internal data model, to the above

  13. A framework for the organization and delivery of systemic treatment.

    Science.gov (United States)

    Vandenberg, T; Coakley, N; Nayler, J; Degrasse, C; Green, E; Mackay, J A; McLennan, C; Smith, A; Wilcock, L; Trudeau, M E

    2009-01-01

    Increasing systemic treatment and shortages of oncology professionals in Canada require innovative approaches to the safe and effective delivery of intravenous (IV) cancer treatment. We conducted a systematic review of the clinical and scientific literature, and an environmental scan of models in Canada, the United Kingdom, Australia, and New Zealand. We then developed a framework for the organization and delivery of IV systemic treatment. The systematic review covered the medline, embase, cinahl, and HealthStar databases. The environmental scan retrieved published and unpublished sources, coupled with a free key word search using the Google search engine. The Systemic Treatment Working Group reviewed the evidence and developed a draft framework using evidence-based analysis, existing recommendations from various jurisdictions, and expert opinion based on experience and consensus. The draft was assessed by Ontario stakeholders and reviewed and approved by Cancer Care Ontario. The poor quantity and quality of the evidence necessitated a consensus-derived model. That model comprises four levels of care determined by a regional systemic treatment program and three integrated structures (integrated cancer programs, affiliate institutions, and satellite institutions), each with a defined scope of practice and a specific organizational framework. New models of care are urgently required beyond large centres, particularly in geographically remote or rural areas. Despite limited applicable evidence, the development and successful implementation of this framework is intended to create sustainable, accessible, quality care and to measurably improve patient outcomes.

  14. Personal health records: retrieving contextual information with Google Custom Search.

    Science.gov (United States)

    Ahsan, Mahmud; Seldon, H Lee; Sayeed, Shohel

    2012-01-01

    Ubiquitous personal health records, which can accompany a person everywhere, are a necessary requirement for ubiquitous healthcare. Contextual information related to health events is important for the diagnosis and treatment of disease and for the maintenance of good health, yet it is seldom recorded in a health record. We describe a dual cellphone-and-Web-based personal health record system which can include 'external' contextual information. Much contextual information is available on the Internet and we can use ontologies to help identify relevant sites and information. But a search engine is required to retrieve information from the Web and developing a customized search engine is beyond our scope, so we can use Google Custom Search API Web service to get contextual data. In this paper we describe a framework which combines a health-and-environment 'knowledge base' or ontology with the Google Custom Search API to retrieve relevant contextual information related to entries in a ubiquitous personal health record.

  15. Building clinical networks: a developmental evaluation framework.

    Science.gov (United States)

    Carswell, Peter; Manning, Benjamin; Long, Janet; Braithwaite, Jeffrey

    2014-05-01

    Clinical networks have been designed as a cross-organisational mechanism to plan and deliver health services. With recent concerns about the effectiveness of these structures, it is timely to consider an evidence-informed approach for how they can be developed and evaluated. To document an evaluation framework for clinical networks by drawing on the network evaluation literature and a 5-year study of clinical networks. We searched literature in three domains: network evaluation, factors that aid or inhibit network development, and on robust methods to measure network characteristics. This material was used to build a framework required for effective developmental evaluation. The framework's architecture identifies three stages of clinical network development; partner selection, network design and network management. Within each stage is evidence about factors that act as facilitators and barriers to network growth. These factors can be used to measure progress via appropriate methods and tools. The framework can provide for network growth and support informed decisions about progress. For the first time in one place a framework incorporating rigorous methods and tools can identify factors known to affect the development of clinical networks. The target user group is internal stakeholders who need to conduct developmental evaluation to inform key decisions along their network's developmental pathway.

  16. Global polar geospatial information service retrieval based on search engine and ontology reasoning

    Science.gov (United States)

    Chen, Nengcheng; E, Dongcheng; Di, Liping; Gong, Jianya; Chen, Zeqiang

    2007-01-01

    In order to improve the access precision of polar geospatial information service on web, a new methodology for retrieving global spatial information services based on geospatial service search and ontology reasoning is proposed, the geospatial service search is implemented to find the coarse service from web, the ontology reasoning is designed to find the refined service from the coarse service. The proposed framework includes standardized distributed geospatial web services, a geospatial service search engine, an extended UDDI registry, and a multi-protocol geospatial information service client. Some key technologies addressed include service discovery based on search engine and service ontology modeling and reasoning in the Antarctic geospatial context. Finally, an Antarctica multi protocol OWS portal prototype based on the proposed methodology is introduced.

  17. Search for new light bosons in high energy astronomy

    International Nuclear Information System (INIS)

    Wouters, Denis

    2014-01-01

    High-Energy astronomy studies the most violent phenomena in the universe with observations in a large spectrum of energies ranging from X rays to very high energy gamma rays (1 keV - 100 TeV). Such phenomena could be for instance supernovae explosions and their remnants, pulsars and pulsar wind nebulae or ultra relativistic jets formation by active galactic nuclei. Understanding these phenomena requires to use well-known particle physics processes. By means of high energy photons, studying such phenomena enables one to search for physics beyond the standard model. Concepts regarding the emission and propagation of high-energy photons are introduced and applied to study their emission by extragalactic sources and to constrain the extragalactic background light which affects their propagation. In this thesis, these high-energy extragalactic emitters are observed in order to search for new light bosons such as axion-like particles (ALPs). The theoretical framework of this family of hypothetical particles is reviewed as well as the associated phenomenology. In particular, because of their coupling to two photons, ALPs oscillate with photons in an external magnetic field. A new signature of such oscillations in turbulent magnetic fields, under the form of stochastic irregularities in the source energy spectrum, is introduced and discussed. A search for ALPs with the HESS telescopes with this new signature is presented, resulting in the first constraints on ALPs parameters coming from high-energy astronomy. Current constraints on ALPs at very low masses are improved by searching for the same signature in X-ray observations. An extension of these constraints to scalar field models for modified gravity in the framework of dark energy is then discussed. The potential of the search for ALPs with CTA, the prospected gamma-ray astronomy instrument, is eventually studied; in particular, a new observable is proposed that relies on the high number of sources that are expected to

  18. A competency framework for librarians involved in systematic reviews.

    Science.gov (United States)

    Townsend, Whitney A; Anderson, Patricia F; Ginier, Emily C; MacEachern, Mark P; Saylor, Kate M; Shipman, Barbara L; Smith, Judith E

    2017-07-01

    The project identified a set of core competencies for librarians who are involved in systematic reviews. A team of seven informationists with broad systematic review experience examined existing systematic review standards, conducted a literature search, and used their own expertise to identify core competencies and skills that are necessary to undertake various roles in systematic review projects. The team identified a total of six competencies for librarian involvement in systematic reviews: "Systematic review foundations," "Process management and communication," "Research methodology," "Comprehensive searching," "Data management," and "Reporting." Within each competency are the associated skills and knowledge pieces (indicators). Competence can be measured using an adaptation of Miller's Pyramid for Clinical Assessment, either through self-assessment or identification of formal assessment instruments. The Systematic Review Competencies Framework provides a standards-based, flexible way for librarians and organizations to identify areas of competence and areas in need of development to build capacity for systematic review integration. The framework can be used to identify or develop appropriate assessment tools and to target skill development opportunities.

  19. Essential Annotation Schema for Ecology (EASE)-A framework supporting the efficient data annotation and faceted navigation in ecology.

    Science.gov (United States)

    Pfaff, Claas-Thido; Eichenberg, David; Liebergesell, Mario; König-Ries, Birgitta; Wirth, Christian

    2017-01-01

    Ecology has become a data intensive science over the last decades which often relies on the reuse of data in cross-experimental analyses. However, finding data which qualifies for the reuse in a specific context can be challenging. It requires good quality metadata and annotations as well as efficient search strategies. To date, full text search (often on the metadata only) is the most widely used search strategy although it is known to be inaccurate. Faceted navigation is providing a filter mechanism which is based on fine granular metadata, categorizing search objects along numeric and categorical parameters relevant for their discovery. Selecting from these parameters during a full text search creates a system of filters which allows to refine and improve the results towards more relevance. We developed a framework for the efficient annotation and faceted navigation in ecology. It consists of an XML schema for storing the annotation of search objects and is accompanied by a vocabulary focused on ecology to support the annotation process. The framework consolidates ideas which originate from widely accepted metadata standards, textbooks, scientific literature, and vocabularies as well as from expert knowledge contributed by researchers from ecology and adjacent disciplines.

  20. Essential Annotation Schema for Ecology (EASE-A framework supporting the efficient data annotation and faceted navigation in ecology.

    Directory of Open Access Journals (Sweden)

    Claas-Thido Pfaff

    Full Text Available Ecology has become a data intensive science over the last decades which often relies on the reuse of data in cross-experimental analyses. However, finding data which qualifies for the reuse in a specific context can be challenging. It requires good quality metadata and annotations as well as efficient search strategies. To date, full text search (often on the metadata only is the most widely used search strategy although it is known to be inaccurate. Faceted navigation is providing a filter mechanism which is based on fine granular metadata, categorizing search objects along numeric and categorical parameters relevant for their discovery. Selecting from these parameters during a full text search creates a system of filters which allows to refine and improve the results towards more relevance. We developed a framework for the efficient annotation and faceted navigation in ecology. It consists of an XML schema for storing the annotation of search objects and is accompanied by a vocabulary focused on ecology to support the annotation process. The framework consolidates ideas which originate from widely accepted metadata standards, textbooks, scientific literature, and vocabularies as well as from expert knowledge contributed by researchers from ecology and adjacent disciplines.

  1. Simplified Models for LHC New Physics Searches

    International Nuclear Information System (INIS)

    Alves, Daniele; Arkani-Hamed, Nima; Arora, Sanjay; Bai, Yang; Baumgart, Matthew; Berger, Joshua; Butler, Bart; Chang, Spencer; Cheng, Hsin-Chia; Cheung, Clifford; Chivukula, R. Sekhar; Cho, Won Sang; Cotta, Randy; D'Alfonso, Mariarosaria; El Hedri, Sonia; Essig, Rouven; Fitzpatrick, Liam; Fox, Patrick; Franceschini, Roberto

    2012-01-01

    This document proposes a collection of simplified models relevant to the design of new-physics searches at the LHC and the characterization of their results. Both ATLAS and CMS have already presented some results in terms of simplified models, and we encourage them to continue and expand this effort, which supplements both signature-based results and benchmark model interpretations. A simplified model is defined by an effective Lagrangian describing the interactions of a small number of new particles. Simplified models can equally well be described by a small number of masses and cross-sections. These parameters are directly related to collider physics observables, making simplified models a particularly effective framework for evaluating searches and a useful starting point for characterizing positive signals of new physics. This document serves as an official summary of the results from the 'Topologies for Early LHC Searches' workshop, held at SLAC in September of 2010, the purpose of which was to develop a set of representative models that can be used to cover all relevant phase space in experimental searches. Particular emphasis is placed on searches relevant for the first ∼ 50-500 pb -1 of data and those motivated by supersymmetric models. This note largely summarizes material posted at http://lhcnewphysics.org/, which includes simplified model definitions, Monte Carlo material, and supporting contacts within the theory community. We also comment on future developments that may be useful as more data is gathered and analyzed by the experiments.

  2. Simplified Models for LHC New Physics Searches

    Energy Technology Data Exchange (ETDEWEB)

    Alves, Daniele; /SLAC; Arkani-Hamed, Nima; /Princeton, Inst. Advanced Study; Arora, Sanjay; /Rutgers U., Piscataway; Bai, Yang; /SLAC; Baumgart, Matthew; /Johns Hopkins U.; Berger, Joshua; /Cornell U., Phys. Dept.; Buckley, Matthew; /Fermilab; Butler, Bart; /SLAC; Chang, Spencer; /Oregon U. /UC, Davis; Cheng, Hsin-Chia; /UC, Davis; Cheung, Clifford; /UC, Berkeley; Chivukula, R.Sekhar; /Michigan State U.; Cho, Won Sang; /Tokyo U.; Cotta, Randy; /SLAC; D' Alfonso, Mariarosaria; /UC, Santa Barbara; El Hedri, Sonia; /SLAC; Essig, Rouven, (ed.); /SLAC; Evans, Jared A.; /UC, Davis; Fitzpatrick, Liam; /Boston U.; Fox, Patrick; /Fermilab; Franceschini, Roberto; /LPHE, Lausanne /Pittsburgh U. /Argonne /Northwestern U. /Rutgers U., Piscataway /Rutgers U., Piscataway /Carleton U. /CERN /UC, Davis /Wisconsin U., Madison /SLAC /SLAC /SLAC /Rutgers U., Piscataway /Syracuse U. /SLAC /SLAC /Boston U. /Rutgers U., Piscataway /Seoul Natl. U. /Tohoku U. /UC, Santa Barbara /Korea Inst. Advanced Study, Seoul /Harvard U., Phys. Dept. /Michigan U. /Wisconsin U., Madison /Princeton U. /UC, Santa Barbara /Wisconsin U., Madison /Michigan U. /UC, Davis /SUNY, Stony Brook /TRIUMF; /more authors..

    2012-06-01

    This document proposes a collection of simplified models relevant to the design of new-physics searches at the LHC and the characterization of their results. Both ATLAS and CMS have already presented some results in terms of simplified models, and we encourage them to continue and expand this effort, which supplements both signature-based results and benchmark model interpretations. A simplified model is defined by an effective Lagrangian describing the interactions of a small number of new particles. Simplified models can equally well be described by a small number of masses and cross-sections. These parameters are directly related to collider physics observables, making simplified models a particularly effective framework for evaluating searches and a useful starting point for characterizing positive signals of new physics. This document serves as an official summary of the results from the 'Topologies for Early LHC Searches' workshop, held at SLAC in September of 2010, the purpose of which was to develop a set of representative models that can be used to cover all relevant phase space in experimental searches. Particular emphasis is placed on searches relevant for the first {approx} 50-500 pb{sup -1} of data and those motivated by supersymmetric models. This note largely summarizes material posted at http://lhcnewphysics.org/, which includes simplified model definitions, Monte Carlo material, and supporting contacts within the theory community. We also comment on future developments that may be useful as more data is gathered and analyzed by the experiments.

  3. A unified statistical framework for material decomposition using multienergy photon counting x-ray detectors

    International Nuclear Information System (INIS)

    Choi, Jiyoung; Kang, Dong-Goo; Kang, Sunghoon; Sung, Younghun; Ye, Jong Chul

    2013-01-01

    Purpose: Material decomposition using multienergy photon counting x-ray detectors (PCXD) has been an active research area over the past few years. Even with some success, the problem of optimal energy selection and three material decomposition including malignant tissue is still on going research topic, and more systematic studies are required. This paper aims to address this in a unified statistical framework in a mammographic environment.Methods: A unified statistical framework for energy level optimization and decomposition of three materials is proposed. In particular, an energy level optimization algorithm is derived using the theory of the minimum variance unbiased estimator, and an iterative algorithm is proposed for material composition as well as system parameter estimation under the unified statistical estimation framework. To verify the performance of the proposed algorithm, the authors performed simulation studies as well as real experiments using physical breast phantom and ex vivo breast specimen. Quantitative comparisons using various performance measures were conducted, and qualitative performance evaluations for ex vivo breast specimen were also performed by comparing the ground-truth malignant tissue areas identified by radiologists.Results: Both simulation and real experiments confirmed that the optimized energy bins by the proposed method allow better material decomposition quality. Moreover, for the specimen thickness estimation errors up to 2 mm, the proposed method provides good reconstruction results in both simulation and real ex vivo breast phantom experiments compared to existing methods.Conclusions: The proposed statistical framework of PCXD has been successfully applied for the energy optimization and decomposition of three material in a mammographic environment. Experimental results using the physical breast phantom and ex vivo specimen support the practicality of the proposed algorithm

  4. Robust object tacking based on self-adaptive search area

    Science.gov (United States)

    Dong, Taihang; Zhong, Sheng

    2018-02-01

    Discriminative correlation filter (DCF) based trackers have recently achieved excellent performance with great computational efficiency. However, DCF based trackers suffer boundary effects, which result in the unstable performance in challenging situations exhibiting fast motion. In this paper, we propose a novel method to mitigate this side-effect in DCF based trackers. We change the search area according to the prediction of target motion. When the object moves fast, broad search area could alleviate boundary effects and reserve the probability of locating object. When the object moves slowly, narrow search area could prevent effect of useless background information and improve computational efficiency to attain real-time performance. This strategy can impressively soothe boundary effects in situations exhibiting fast motion and motion blur, and it can be used in almost all DCF based trackers. The experiments on OTB benchmark show that the proposed framework improves the performance compared with the baseline trackers.

  5. A Search for Supersymmetric Higgs Bosons in the Di-tau Decay Mode in Proton - Anti-proton Collisions at 1.8 TeV

    Energy Technology Data Exchange (ETDEWEB)

    Connolly, Amy Lynn [Univ. of California, Berkeley, CA (United States)

    2003-01-01

    A search for directly produced Supersymmetric Higgs Bosons has been performed in the di-tau decay channel in 86.3 ± 3.5 pb-1 of data collected by CDF during Run1b at the Tevatron. They search for events where one tau decays to an electron and the other tau decays hadronically. They perform a counting experiment and set limits on the cross section for Higgs production in the high tan β region of the mA-tan β plane. For a benchmark parameter space point where mA = 100 and tan β = 50, they set a 95% confidence level upper limit at 891 pb compared to the theoretically predicted cross section of 122 pb. For events where the tau candidates are not back-to-back, they utilize a di-tau mass reconstruction technique for the first time on hadron collider data. Limits based on a likelihood binned in di-tau mass from non-back-to-back events alone are weaker than the limits obtained from the counting experiment using the full di-tau sample.

  6. A Comparative Analysis of International Frameworks for 21st Century Competences: Implications for National Curriculum Policies

    Science.gov (United States)

    Voogt, Joke; Roblin, Natalie Pareja

    2012-01-01

    National curricula need to change drastically to comply with the competences needed for the 21st century. In this paper eight frameworks describing 21st century competences were analysed. A comprehensive search for information about 21st century competences was conducted across the official websites of the selected frameworks, resulting in 32…

  7. A Linear Time Complexity of Breadth-First Search Using P System with Membrane Division

    Directory of Open Access Journals (Sweden)

    Einallah Salehi

    2013-01-01

    Full Text Available One of the known methods for solving the problems with exponential time complexity such as NP-complete problems is using the brute force algorithms. Recently, a new parallel computational framework called Membrane Computing is introduced which can be applied in brute force algorithms. The usual way to find a solution for the problems with exponential time complexity with Membrane Computing techniques is by P System with active membrane using division rule. It makes an exponential workspace and solves the problems with exponential complexity in a polynomial (even linear time. On the other hand, searching is currently one of the most used methods for finding solution for problems in real life, that the blind search algorithms are accurate, but their time complexity is exponential such as breadth-first search (BFS algorithm. In this paper, we proposed a new approach for implementation of BFS by using P system with division rule technique for first time. The theorem shows time complexity of BSF in this framework on randomly binary trees reduced from O(2d to O(d.

  8. Uma avaliação de descritores de textura baseados em códigos binários locais para classificação de imagens de sensoriamento remoto

    Directory of Open Access Journals (Sweden)

    Marcelo Musci

    Full Text Available O presente trabalho avalia descritores texturais multiescalares invariantes à rotação baseados em Padrões Binários Locais e em Quantização de Fase Local (LPQ para a classificação de uso e cobertura do solo em uma imagem IKONOS-2 e uma imagem Quickbird-2. Os experimentos mostraram que ambas as representações de textura propiciaram elevada acurácia quando combinadas com a informação de variância. Além disso, propõe-se no trabalho um novo descritor formado pela concatenação do histograma de variância e o histograma dos códigos gerados a partir dos Padrões Binários Locais ou da Quantização de Fase Local. Com o novo descritor, não obstante serem comparativamente mais compacto, registraram-se os mesmos índices de desempenho obtidos a partir de histogramas bidimensionais que representam a distribuição conjunta de ambas as variáveis. O último experimento realizado indicou para os descritores baseados nos Padrões Binários Locais ou na Quantização de Fase Local um índice Kappa superior em 0,1 ao que alcançou quando se utilizaram atributos de textura derivados da matriz de co-ocorrência.

  9. An integrative systematic framework helps to reconstruct skeletal evolution of glass sponges (Porifera, Hexactinellida).

    Science.gov (United States)

    Dohrmann, Martin; Kelley, Christopher; Kelly, Michelle; Pisera, Andrzej; Hooper, John N A; Reiswig, Henry M

    2017-01-01

    Glass sponges (Class Hexactinellida) are important components of deep-sea ecosystems and are of interest from geological and materials science perspectives. The reconstruction of their phylogeny with molecular data has only recently begun and shows a better agreement with morphology-based systematics than is typical for other sponge groups, likely because of a greater number of informative morphological characters. However, inconsistencies remain that have far-reaching implications for hypotheses about the evolution of their major skeletal construction types (body plans). Furthermore, less than half of all described extant genera have been sampled for molecular systematics, and several taxa important for understanding skeletal evolution are still missing. Increased taxon sampling for molecular phylogenetics of this group is therefore urgently needed. However, due to their remote habitat and often poorly preserved museum material, sequencing all 126 currently recognized extant genera will be difficult to achieve. Utilizing morphological data to incorporate unsequenced taxa into an integrative systematics framework therefore holds great promise, but it is unclear which methodological approach best suits this task. Here, we increase the taxon sampling of four previously established molecular markers (18S, 28S, and 16S ribosomal DNA, as well as cytochrome oxidase subunit I) by 12 genera, for the first time including representatives of the order Aulocalycoida and the type genus of Dactylocalycidae, taxa that are key to understanding hexactinellid body plan evolution. Phylogenetic analyses suggest that Aulocalycoida is diphyletic and provide further support for the paraphyly of order Hexactinosida; hence these orders are abolished from the Linnean classification. We further assembled morphological character matrices to integrate so far unsequenced genera into phylogenetic analyses in maximum parsimony (MP), maximum likelihood (ML), Bayesian, and morphology-based binning

  10. Search for weakly interacting massive particles with the Cryogenic Dark Matter Search experiment

    Energy Technology Data Exchange (ETDEWEB)

    Saab, Tarek [Stanford U.

    2002-01-01

    From individual galaxies, to clusters of galaxies, to in between the cushions of your sofa, Dark Matter appears to be pervasive on every scale. With increasing accuracy, recent astrophysical measurements, from a variety of experiments, are arriving at the following cosmological model : a flat cosmology (Ωk = 0) with matter and energy densities contributing roughly 1/3 and 2/3 (Ωm = 0.35, ΩΛ = 0.65). Of the matter contribution, it appears that only ~ 10% (Ωb ~ 0.04) is attributable to baryons. Astrophysical measurements constrain the remaining matter to be non-realtivistic, interacting primarily gravitationally. Various theoretical models for such Dark Matter exist. A leading candidate for the non-baryonic matter are Weakly Interacting Massive Particles (dubbed WIMPS). These particles, and their relic density may be naturally explained within the framework of Super-Symmetry theories. SuperSymmetry also offers predictions as to the scattering rates of WIMPs with baryonic matter allowing for the design and tailoring of experiments that search specifically for the WIMPs. The Cryogenic Dark Matter Search experiment is searching for evidence of WIMP interactions in crystals of Ge and Si. Using cryogenic detector technology to measure both the phonon and ionization response to a particle recoil the CDMS detectors are able to discriminate between electron and nuclear recoils, thus reducing the large rates of electron recoil backgrounds to levels with which a Dark Matter search is not only feasible, but far-reaching. This thesis will describe in some detail the physical principles behind the CDMS detector technology, highlighting the final step in the evolution of the detector design and characterization techniques. In addition, data from a 100 day long exposure of the current run at the Stanford Underground Facility will be presented, with focus given to detector performance as well as to the implications on allowable WIMP mass - cross-section parameter space.

  11. Implementation of a Parameterization Framework for Cybersecurity Laboratories

    Science.gov (United States)

    2017-03-01

    this collection of information is estimated to average 1 hour per response, including the time for reviewing instruction, searching existing data ...that the student performed each step of an exercise to help instructors assess the level of learning by each student. The framework should automate ... automated assessment tools (AATs) created to help assess how students perform in programming courses. In the paper, “Are Automated Assessment Tools

  12. Search for radions at LEP2

    International Nuclear Information System (INIS)

    Abbiendi, G.; Ainsley, C.; Akesson, P.F.

    2005-01-01

    A new scalar resonance, called the radion, with couplings to fermions and bosons similar to those of the Higgs boson, is predicted in the framework of Randall-Sundrum models, proposed solutions to the hierarchy problem with one extra dimension. An important distinction between the radion and the Higgs boson is that the radion would couple directly to gluon pairs, and in particular its decay products would include a significant fraction of gluon jets. The radion has the same quantum numbers as the Standard Model (SM) Higgs boson, and therefore they can mix, with the resulting mass eigenstates having properties different from those of the SM Higgs boson. Existing searches for the Higgs bosons are sensitive to the possible production and decay of radions and Higgs bosons in these models. For the first time, searches for the SM Higgs boson and flavour-independent and decay-mode independent searches for a neutral Higgs boson are used in combination to explore the parameter space of the Randall-Sundrum model. In the dataset recorded by the OPAL experiment at LEP, no evidence for radion or Higgs particle production was observed in any of those searches at centre-of-mass energies up to 209 GeV. The results are used to set limits on the radion and Higgs boson masses. For all parameters of the Randall-Sundrum model, the data exclude masses below 58 GeV for the mass eigenstate which becomes the Higgs boson in the no-mixing limit

  13. Development of a parallel trigger framework for rare decay searches

    CERN Document Server

    Pantaleo, Felice

    The simplicity of kaon decays (few decay channels, low final-state multiplicities) enable the possibility to reach an excellent sensitivity in the searches of lepton flavor violating decays. The experimental characteristics of decays like $K^+\\to \\pi^- \\mu^+ \\mu^+$ are very clear and allow an efficient background rejection. However, the measurement of this kind of events requires the production of a remarkable number of kaon decays. The bandwidth of tape recording system currently available does not allow the storage of all the produced events. A multi-stage selection of the potentially interesting events is required (trigger). At NA62, a first selection is done in real-time (response time $<1$ ms) by the level 0 trigger. The level 0 trigger is based on programmable logic (FPGA) that does not allow the same flexibility of the processors used for software programmable computers. The performance of parallel architectures like multi-cores CPUs and GPUs (Graphics Processing Units), located on computers grap...

  14. A 222 energy bins response matrix for a {sup 6}Lil scintillator Bss system

    Energy Technology Data Exchange (ETDEWEB)

    Lacerda, M. A. S. [Centro de Desenvolvimento da Tecnologia Nuclear, Laboratorio de Calibracao de Dosimetros, Av. Pte. Antonio Carlos 6627, 31270-901 Pampulha, Belo Horizonte, Minas Gerais (Brazil); Vega C, H. R. [Universidad Autonoma de Zacatecas, Unidad Academica de Estudios Nucleares, Cipres No. 10, Fracc. La Penuela, 98068 Zacatecas, Zac. (Mexico); Mendez V, R. [Centro de Investigaciones Energeticas, Medioambientales y Tecnologicas, Laboratorio de Patrones Neutronicos, Av. Complutense 22, 28040 Madrid (Spain); Lorente F, A.; Ibanez F, S.; Gallego D, E., E-mail: masl@cdtn.br [Universidad Politecnica de Madrid, Departamento de Ingenieria Nuclear, 28006 Madrid (Spain)

    2016-10-15

    A new response matrix was calculated for a Bonner Sphere Spectrometer (Bss) with a {sup 6}Lil(Eu) scintillator. We utilized the Monte Carlo N-particle radiation transport code MCNPX, version 2.7.0, with Endf/B-VII.0 nuclear data library to calculate the responses for 6 spheres and the bare detector, for energies varying from 9.441 E(-10) MeV to 105.9 MeV, with 20 equal-log(E)-width bins per energy decade, totalizing 222 energy groups. A Bss, like the modeled in this work, was utilized to measure the neutron spectrum generated by the {sup 241}AmBe source of the Universidad Politecnica de Madrid. From the count rates obtained with this Bss system we unfolded neutron spectrum utilizing the BUNKIUT code for 31 energy bins (UTA-4 response matrix) and the MAXED code with the new calculated response functions. We compared spectra obtained with these Bss system / unfold codes with that obtained from measurements performed with a Bss system constituted of 12 spheres with a spherical {sup 3}He Sp-9 counter (Centronic Ltd., UK) and MAXED code with the system-specific response functions (Bss-CIEMAT). A relatively good agreement was observed between our response matrix and that calculated by other authors. In general, we observed an improvement in the agreement as the energy increases. However, higher discrepancies were observed for energies close to 1-E(-8) MeV and, mainly, for energies above 20 MeV. These discrepancies were mainly attributed to the differences in cross-section libraries employed. The ambient dose equivalent (H (10)) calculated with the {sup 6}Lil-MAXED showed a good agreement with values measured with the neutron area monitor Bert hold Lb 6411 and within 12% the value obtained with another Bss system (Bss-CIEMAT). The response matrix calculated in this work can be utilized together with the MAXED code to generate neutron spectra with a good energy resolution up to 20 MeV. Some additional tests are being done to validate this response matrix and improve the

  15. GeoSearch: A lightweight broking middleware for geospatial resources discovery

    Science.gov (United States)

    Gui, Z.; Yang, C.; Liu, K.; Xia, J.

    2012-12-01

    With petabytes of geodata, thousands of geospatial web services available over the Internet, it is critical to support geoscience research and applications by finding the best-fit geospatial resources from the massive and heterogeneous resources. Past decades' developments witnessed the operation of many service components to facilitate geospatial resource management and discovery. However, efficient and accurate geospatial resource discovery is still a big challenge due to the following reasons: 1)The entry barriers (also called "learning curves") hinder the usability of discovery services to end users. Different portals and catalogues always adopt various access protocols, metadata formats and GUI styles to organize, present and publish metadata. It is hard for end users to learn all these technical details and differences. 2)The cost for federating heterogeneous services is high. To provide sufficient resources and facilitate data discovery, many registries adopt periodic harvesting mechanism to retrieve metadata from other federated catalogues. These time-consuming processes lead to network and storage burdens, data redundancy, and also the overhead of maintaining data consistency. 3)The heterogeneous semantics issues in data discovery. Since the keyword matching is still the primary search method in many operational discovery services, the search accuracy (precision and recall) is hard to guarantee. Semantic technologies (such as semantic reasoning and similarity evaluation) offer a solution to solve these issues. However, integrating semantic technologies with existing service is challenging due to the expandability limitations on the service frameworks and metadata templates. 4)The capabilities to help users make final selection are inadequate. Most of the existing search portals lack intuitive and diverse information visualization methods and functions (sort, filter) to present, explore and analyze search results. Furthermore, the presentation of the value

  16. PEER REVIEW (Correlation between GATA-3, Ki67 and p53 expressions to Histopathology grading of Breast Cancer bin Makassar, Indonesia)

    OpenAIRE

    Islam, Andi Asadul

    2016-01-01

    - PEER REVIEW Judul karya Ilmiah (artikel): Correlation between GATA-3, Ki67 and p53 expressions to Histopathology grading of Breast Cancer bin Makassar, Indonesia : 9 Orang : Penulis Ketiga : a. Nama Jurnal : Cancer Research Journal b. Nomor ISSN : 2330-8192, E: 2330-8214 c. Volume,nomor, bulan, tahun : Volume 4, No. 3 Tahun 2016 d. Penerbit : Science PG e. DOI artikel (Jika ada) : 10.11648/j.crj .20160403.11 f. Alamat web Jurnal : www.sciencepublishingg...

  17. Essential Annotation Schema for Ecology (EASE)—A framework supporting the efficient data annotation and faceted navigation in ecology

    Science.gov (United States)

    Eichenberg, David; Liebergesell, Mario; König-Ries, Birgitta; Wirth, Christian

    2017-01-01

    Ecology has become a data intensive science over the last decades which often relies on the reuse of data in cross-experimental analyses. However, finding data which qualifies for the reuse in a specific context can be challenging. It requires good quality metadata and annotations as well as efficient search strategies. To date, full text search (often on the metadata only) is the most widely used search strategy although it is known to be inaccurate. Faceted navigation is providing a filter mechanism which is based on fine granular metadata, categorizing search objects along numeric and categorical parameters relevant for their discovery. Selecting from these parameters during a full text search creates a system of filters which allows to refine and improve the results towards more relevance. We developed a framework for the efficient annotation and faceted navigation in ecology. It consists of an XML schema for storing the annotation of search objects and is accompanied by a vocabulary focused on ecology to support the annotation process. The framework consolidates ideas which originate from widely accepted metadata standards, textbooks, scientific literature, and vocabularies as well as from expert knowledge contributed by researchers from ecology and adjacent disciplines. PMID:29023519

  18. OpenDrift v1.0: a generic framework for trajectory modelling

    Science.gov (United States)

    Dagestad, Knut-Frode; Röhrs, Johannes; Breivik, Øyvind; Ådlandsvik, Bjørn

    2018-04-01

    OpenDrift is an open-source Python-based framework for Lagrangian particle modelling under development at the Norwegian Meteorological Institute with contributions from the wider scientific community. The framework is highly generic and modular, and is designed to be used for any type of drift calculations in the ocean or atmosphere. A specific module within the OpenDrift framework corresponds to a Lagrangian particle model in the traditional sense. A number of modules have already been developed, including an oil drift module, a stochastic search-and-rescue module, a pelagic egg module, and a basic module for atmospheric drift. The framework allows for the ingestion of an unspecified number of forcing fields (scalar and vectorial) from various sources, including Eulerian ocean, atmosphere and wave models, but also measurements or a priori values for the same variables. A basic backtracking mechanism is inherent, using sign reversal of the total displacement vector and negative time stepping. OpenDrift is fast and simple to set up and use on Linux, Mac and Windows environments, and can be used with minimal or no Python experience. It is designed for flexibility, and researchers may easily adapt or write modules for their specific purpose. OpenDrift is also designed for performance, and simulations with millions of particles may be performed on a laptop. Further, OpenDrift is designed for robustness and is in daily operational use for emergency preparedness modelling (oil drift, search and rescue, and drifting ships) at the Norwegian Meteorological Institute.

  19. Face Image Retrieval of Efficient Sparse Code words and Multiple Attribute in Binning Image

    Directory of Open Access Journals (Sweden)

    Suchitra S

    2017-08-01

    Full Text Available ABSTRACT In photography, face recognition and face retrieval play an important role in many applications such as security, criminology and image forensics. Advancements in face recognition make easier for identity matching of an individual with attributes. Latest development in computer vision technologies enables us to extract facial attributes from the input image and provide similar image results. In this paper, we propose a novel LOP and sparse codewords method to provide similar matching results with respect to input query image. To improve accuracy in image results with input image and dynamic facial attributes, Local octal pattern algorithm [LOP] and Sparse codeword applied in offline and online. The offline and online procedures in face image binning techniques apply with sparse code. Experimental results with Pubfig dataset shows that the proposed LOP along with sparse codewords able to provide matching results with increased accuracy of 90%.

  20. Enhancing discovery in spatial data infrastructures using a search engine

    Directory of Open Access Journals (Sweden)

    Paolo Corti

    2018-05-01

    Full Text Available A spatial data infrastructure (SDI is a framework of geospatial data, metadata, users and tools intended to provide an efficient and flexible way to use spatial information. One of the key software components of an SDI is the catalogue service which is needed to discover, query and manage the metadata. Catalogue services in an SDI are typically based on the Open Geospatial Consortium (OGC Catalogue Service for the Web (CSW standard which defines common interfaces for accessing the metadata information. A search engine is a software system capable of supporting fast and reliable search, which may use ‘any means necessary’ to get users to the resources they need quickly and efficiently. These techniques may include full text search, natural language processing, weighted results, fuzzy tolerance results, faceting, hit highlighting, recommendations and many others. In this paper we present an example of a search engine being added to an SDI to improve search against large collections of geospatial datasets. The Centre for Geographic Analysis (CGA at Harvard University re-engineered the search component of its public domain SDI (Harvard WorldMap which is based on the GeoNode platform. A search engine was added to the SDI stack to enhance the CSW catalogue discovery abilities. It is now possible to discover spatial datasets from metadata by using the standard search operations of the catalogue and to take advantage of the new abilities of the search engine, to return relevant and reliable content to SDI users.

  1. Searches for SUSY at LHC

    International Nuclear Information System (INIS)

    Kharchilava, A.

    1997-01-01

    One of the main motivations of experiments at the LHC is to search for SUSY particles. The talk is based on recent analyses, performed by CMS Collaboration, within the framework of the Supergravity motivated minimal SUSY extension of the Standard Model. The emphasis is put on leptonic channels. The strategies for obtaining experimental signatures for strongly and weakly interacting sparticles productions, as well as examples of determination of SUSY masses and model parameters are discussed. The domain of parameter space where SUSY can be discovered is investigated. Results show, that if SUSY is of relevance at Electro-Weak scale it could hardly escape detection at LHC. (author)

  2. Protein search for multiple targets on DNA

    Energy Technology Data Exchange (ETDEWEB)

    Lange, Martin [Johannes Gutenberg University, Mainz 55122 (Germany); Department of Chemistry, Rice University, Houston, Texas 77005 (United States); Kochugaeva, Maria [Department of Chemistry, Rice University, Houston, Texas 77005 (United States); Kolomeisky, Anatoly B., E-mail: tolya@rice.edu [Department of Chemistry, Rice University, Houston, Texas 77005 (United States); Center for Theoretical Biological Physics, Rice University, Houston, Texas 77005 (United States)

    2015-09-14

    Protein-DNA interactions are crucial for all biological processes. One of the most important fundamental aspects of these interactions is the process of protein searching and recognizing specific binding sites on DNA. A large number of experimental and theoretical investigations have been devoted to uncovering the molecular description of these phenomena, but many aspects of the mechanisms of protein search for the targets on DNA remain not well understood. One of the most intriguing problems is the role of multiple targets in protein search dynamics. Using a recently developed theoretical framework we analyze this question in detail. Our method is based on a discrete-state stochastic approach that takes into account most relevant physical-chemical processes and leads to fully analytical description of all dynamic properties. Specifically, systems with two and three targets have been explicitly investigated. It is found that multiple targets in most cases accelerate the search in comparison with a single target situation. However, the acceleration is not always proportional to the number of targets. Surprisingly, there are even situations when it takes longer to find one of the multiple targets in comparison with the single target. It depends on the spatial position of the targets, distances between them, average scanning lengths of protein molecules on DNA, and the total DNA lengths. Physical-chemical explanations of observed results are presented. Our predictions are compared with experimental observations as well as with results from a continuum theory for the protein search. Extensive Monte Carlo computer simulations fully support our theoretical calculations.

  3. Self-Efficacy and Its Relationship with Social Skills and the Quality of Decision-Making among the Students of Prince Sattam Bin Abdul-Aziz University

    Science.gov (United States)

    Al-mehsin, Salama Aqeel

    2017-01-01

    The present study aimed to reveal the self-efficacy and social skills and their relationship to the quality of decision-making at Prince Sattam bin Abdulaziz University students, and determine the extent of the contribution of self-efficacy and social skills to the quality of decision-making. To achieve this, a questionnaire was built to identify…

  4. Variation of the height of the grain bed of an indirect solar bin dryer; Variacion de la altura del lecho del grano en un secador solar indirecto

    Energy Technology Data Exchange (ETDEWEB)

    Sima, Efrain; Alvarez, Gabriela; Garcia, Saul [CENIDET, Cuernavaca, Morelos (Mexico)

    2000-07-01

    This paper presents the effect of the variation of the size of the grain bed of an indirect solar bin dryer. This solar dryer was designed and built at the Instituto Tecnologico de Zacatepec and Sima performed the thermal evaluation. The solar bin dryer consists of a bin dryer of 0.92 m diameter and 1 m height (the maximum height of the grain bed is 0.6 m). a 2 m{sup 2} solar collector, a blower and an electronic card to control the inlet air flow of the bin. A load of 36 kg, 45 kg, 52 kg and 64 kg of corn were dried. The heights of the grain were 7.5 cm, 10 cm, 12.5 cm and 17 cm respectively. Solar radiation, inlet air velocity of the solar collector, pressure drop, grain temperature and humidity, ambient temperature and humidity of the drying air were recorded. The initial grain humidity was 27.2% and the final was 11.8%. [Spanish] En este trabajo se presenta el efecto de la variacion del lecho del grano en el proceso de secado de maiz, en un prototipo de secador solar de tipo indirecto. El secador fue disenado y construido en el Tecnologico de Zacatepec y evaluado por Sima, consta de una camara de secado de 0.92 m de diametro y una altura de 1 m. (la altura del lecho maximo de grano posible es de 0.6 m.), un colector solar con un area de 2 m{sup 2}, un extractor de aire y un control electronico para el flujo de aire. El secado de maiz se llevo a cabo con cargas de maiz de 36, 45, 52 y 64 kg. Las alturas en el lecho del grano fueron 7.5, 10, 12.5 y 17 cm. Para cada altura de lecho de grano se realizo una prueba. Durante cada prueba se realizaron mediciones de: radiacion solar, velocidad del aire a la entrada, caida de presion, temperatura del grano, humedad del grano, temperatura del aire ambiente, temperatura y humedad del aire de secado a la entrada y salida del secador. La humedad inicial del grano fue alrededor de 27.2% y la final de 11.8%.

  5. Searching for gravitational waves from rotating neutron stars

    Indian Academy of Sciences (India)

    project located near Pisa with a baseline of 3 km, GEO600, a British/German interferome- ... In order to recover the whole power in one frequency bin one has to 'cor- .... these factors can be easily included in the full analysis and will not ...

  6. A Rule-Based Local Search Algorithm for General Shift Design Problems in Airport Ground Handling

    DEFF Research Database (Denmark)

    Clausen, Tommy

    We consider a generalized version of the shift design problem where shifts are created to cover a multiskilled demand and fit the parameters of the workforce. We present a collection of constraints and objectives for the generalized shift design problem. A local search solution framework with mul......We consider a generalized version of the shift design problem where shifts are created to cover a multiskilled demand and fit the parameters of the workforce. We present a collection of constraints and objectives for the generalized shift design problem. A local search solution framework...... with multiple neighborhoods and a loosely coupled rule engine based on simulated annealing is presented. Computational experiments on real-life data from various airport ground handling organization show the performance and flexibility of the proposed algorithm....

  7. HistFitter software framework for statistical data analysis

    CERN Document Server

    Baak, M.; Côte, D.; Koutsman, A.; Lorenz, J.; Short, D.

    2015-01-01

    We present a software framework for statistical data analysis, called HistFitter, that has been used extensively by the ATLAS Collaboration to analyze big datasets originating from proton-proton collisions at the Large Hadron Collider at CERN. Since 2012 HistFitter has been the standard statistical tool in searches for supersymmetric particles performed by ATLAS. HistFitter is a programmable and flexible framework to build, book-keep, fit, interpret and present results of data models of nearly arbitrary complexity. Starting from an object-oriented configuration, defined by users, the framework builds probability density functions that are automatically fitted to data and interpreted with statistical tests. A key innovation of HistFitter is its design, which is rooted in core analysis strategies of particle physics. The concepts of control, signal and validation regions are woven into its very fabric. These are progressively treated with statistically rigorous built-in methods. Being capable of working with mu...

  8. Configurable User Interface Framework for Data Discovery in Cross-Disciplinary and Citizen Science

    Science.gov (United States)

    Rozell, E.; Wang, H.; West, P.; Zednik, S.; Fox, P.

    2012-04-01

    Use cases for data discovery and analysis vary widely when looking across disciplines and levels of expertise. Domain experts across disciplines may have a thorough understanding of self-describing data formats, such as netCDF, and the software packages that are compatible. However, they may be unfamiliar with specific vocabulary terms used to describe the data parameters or instrument packages in someone else's collection, which are often useful in data discovery. Citizen scientists may struggle with both expert vocabularies and knowledge of existing tools for analyzing and visualizing data. There are some solutions for each problem individually. For expert vocabularies, semantic technologies like the Resource Description Framework (RDF) have been used to map terms from an expert vocabulary to layperson terminology. For data analysis and visualization, tools can be mapped to data products using semantic technologies as well. This presentation discusses a solution to both problems based on the S2S Framework, a configurable user interface (UI) framework for Web services. S2S unifies the two solutions previously described using a data service abstraction ("search services") and a UI abstraction ("widgets"). Using the OWL Web Ontology Language, S2S defines a vocabulary for describing search services and their outputs, and the compatibility of those outputs with UI widgets. By linking search service outputs to widgets, S2S can automatically compose UIs for search and analysis of data, making it easier for citizen scientists to manipulate data. We have also created Linked Data widgets for S2S, which can leverage distributed RDF resources to present alternative views of expert vocabularies. This presentation covers some examples where we have applied these solutions to improve data discovery for both cross-disciplinary and non-expert users.

  9. Transits maghrébins à Istanbul. Trajectoires, profils et stratégies

    Directory of Open Access Journals (Sweden)

    Jean-François Pérouse

    2012-03-01

    Full Text Available Istanbul est devenu depuis le début des années 1990 un foyer important, à la fois polarisateur et redistributeur, dans le système complexe des migrations internationales, dont les migrations de transit, des pays pauvres vers les pays riches, constituent une des dimensions les plus saillantes. Dans ce cadre, on s’efforce ici d’examiner le cas des Maghrébins qui, s’ils ne forment pas numériquement le “groupe” le plus en vue, n’en offrent pas moins une configuration intéressante, tant par les types de trajectoires qui les conduisent à Istanbul que par les stratégies de survie et de “faire communauté” dans la métropole, que par les modalités de sortie vers les horizons convoités. On insiste ici sur les diverses modalités de transit, la prégnance des identités nationales, l’efficace irremplaçable des liens familiaux, la faible insertion dans le marché du travail métropolitain et les redéfinitions des rapports de genre occasionnées.

  10. Evaluation framework for K-best sphere decoders

    KAUST Repository

    Shen, Chungan

    2010-08-01

    While Maximum-Likelihood (ML) is the optimum decoding scheme for most communication scenarios, practical implementation difficulties limit its use, especially for Multiple Input Multiple Output (MIMO) systems with a large number of transmit or receive antennas. Tree-searching type decoder structures such as Sphere decoder and K-best decoder present an interesting trade-off between complexity and performance. Many algorithmic developments and VLSI implementations have been reported in literature with widely varying performance to area and power metrics. In this semi-tutorial paper we present a holistic view of different Sphere decoding techniques and K-best decoding techniques, identifying the key algorithmic and implementation trade-offs. We establish a consistent benchmark framework to investigate and compare the delay cost, power cost, and power-delay-product cost incurred by each method. Finally, using the framework, we propose and analyze a novel architecture and compare that to other published approaches. Our goal is to explicitly elucidate the overall advantages and disadvantages of each proposed algorithms in one coherent framework. © 2010 World Scientific Publishing Company.

  11. Development of an international comorbidity education framework.

    Science.gov (United States)

    Lawson, C; Pati, S; Green, J; Messina, G; Strömberg, A; Nante, N; Golinelli, D; Verzuri, A; White, S; Jaarsma, T; Walsh, P; Lonsdale, P; Kadam, U T

    2017-08-01

    The increasing number of people living with multiple chronic conditions in addition to an index condition has become an international healthcare priority. Health education curricula have been developed alongside single condition frameworks in health service policy and practice and need redesigning to incorporate optimal management of multiple conditions. Our aims were to evaluate current teaching and learning about comorbidity care amongst the global population of healthcare students from different disciplines and to develop an International Comorbidity Education Framework (ICEF) for incorporating comorbidity concepts into health education. We surveyed nursing, medical and pharmacy students from England, India, Italy and Sweden to evaluate their understanding of comorbidity care. A list of core comorbidity content was constructed by an international group of higher education academics and clinicians from the same disciplines, by searching current curricula and analysing clinical frameworks and the student survey data. This list was used to develop the International Comorbidity Education Framework. The survey sample consisted of 917 students from England (42%), India (48%), Italy (8%) and Sweden (2%). The majority of students across all disciplines said that they lacked knowledge, training and confidence in comorbidity care and were unable to identify specific teaching on comorbidities. All student groups wanted further comorbidity training. The health education institution representatives found no specific references to comorbidity in current health education curricula. Current clinical frameworks were used to develop an agreed list of core comorbidity content and hence an International Comorbidity Education Framework. Based on consultation with academics and clinicians and on student feedback we developed an International Comorbidity Education Framework to promote the integration of comorbidity concepts into current healthcare curricula. Copyright © 2017 Elsevier

  12. A Community Assessmet of Biosignatures and their Frameworks

    Science.gov (United States)

    Domagal-Goldman, Shawn David; Nexus for Exoplanet Systems Science (NExSS)

    2018-01-01

    The Nexus for Exoplanet Systems Science (NExSS) organized a workshop to assess the current state of exoplanet biosignature research. Here, we review the products from that workshop. This includes: 1) a review of previously-proposed biosignatures in both the atmosphere and on the sruface of an exoplanet; 2) the need for context in assessing those biosignatures; 3) the potential for a Bayesian framework to formalize and quantify the need for context; 4) the interdisciplinary research required to advance that Bayesian framework; and 5) the missions that would search for biosignatures, including required contextual observations. Here we will revie those findings, the future path for research they suggest, and the implications they have for future missions, including both ground- and space-based missions.

  13. Kepler Science Operations Center Pipeline Framework

    Science.gov (United States)

    Klaus, Todd C.; McCauliff, Sean; Cote, Miles T.; Girouard, Forrest R.; Wohler, Bill; Allen, Christopher; Middour, Christopher; Caldwell, Douglas A.; Jenkins, Jon M.

    2010-01-01

    The Kepler mission is designed to continuously monitor up to 170,000 stars at a 30 minute cadence for 3.5 years searching for Earth-size planets. The data are processed at the Science Operations Center (SOC) at NASA Ames Research Center. Because of the large volume of data and the memory and CPU-intensive nature of the analysis, significant computing hardware is required. We have developed generic pipeline framework software that is used to distribute and synchronize the processing across a cluster of CPUs and to manage the resulting products. The framework is written in Java and is therefore platform-independent, and scales from a single, standalone workstation (for development and research on small data sets) to a full cluster of homogeneous or heterogeneous hardware with minimal configuration changes. A plug-in architecture provides customized control of the unit of work without the need to modify the framework itself. Distributed transaction services provide for atomic storage of pipeline products for a unit of work across a relational database and the custom Kepler DB. Generic parameter management and data accountability services are provided to record the parameter values, software versions, and other meta-data used for each pipeline execution. A graphical console allows for the configuration, execution, and monitoring of pipelines. An alert and metrics subsystem is used to monitor the health and performance of the pipeline. The framework was developed for the Kepler project based on Kepler requirements, but the framework itself is generic and could be used for a variety of applications where these features are needed.

  14. An Elitist Multiobjective Tabu Search for Optimal Design of Groundwater Remediation Systems.

    Science.gov (United States)

    Yang, Yun; Wu, Jianfeng; Wang, Jinguo; Zhou, Zhifang

    2017-11-01

    This study presents a new multiobjective evolutionary algorithm (MOEA), the elitist multiobjective tabu search (EMOTS), and incorporates it with MODFLOW/MT3DMS to develop a groundwater simulation-optimization (SO) framework based on modular design for optimal design of groundwater remediation systems using pump-and-treat (PAT) technique. The most notable improvement of EMOTS over the original multiple objective tabu search (MOTS) lies in the elitist strategy, selection strategy, and neighborhood move rule. The elitist strategy is to maintain all nondominated solutions within later search process for better converging to the true Pareto front. The elitism-based selection operator is modified to choose two most remote solutions from current candidate list as seed solutions to increase the diversity of searching space. Moreover, neighborhood solutions are uniformly generated using the Latin hypercube sampling (LHS) in the bounded neighborhood space around each seed solution. To demonstrate the performance of the EMOTS, we consider a synthetic groundwater remediation example. Problem formulations consist of two objective functions with continuous decision variables of pumping rates while meeting water quality requirements. Especially, sensitivity analysis is evaluated through the synthetic case for determination of optimal combination of the heuristic parameters. Furthermore, the EMOTS is successfully applied to evaluate remediation options at the field site of the Massachusetts Military Reservation (MMR) in Cape Cod, Massachusetts. With both the hypothetical and the large-scale field remediation sites, the EMOTS-based SO framework is demonstrated to outperform the original MOTS in achieving the performance metrics of optimality and diversity of nondominated frontiers with desirable stability and robustness. © 2017, National Ground Water Association.

  15. Guided basin-hopping search of small boron clusters with density functional theory

    Energy Technology Data Exchange (ETDEWEB)

    Ng, Wei Chun; Yoon, Tiem Leong [School of Physics, Universiti Sains Malaysia, 11800 USM, Penang (Malaysia); Lim, Thong Leng [Faculty of Engineering and Technology, Multimedia University, Melacca Campus, 75450 Melaka (Malaysia)

    2015-04-24

    The search for the ground state structures of Boron clusters has been a difficult computational task due to the unique metalloid nature of Boron atom. Previous research works had overcome the problem in the search of the Boron ground-state structures by adding symmetry constraints prior to the process of locating the local minima in the potential energy surface (PES) of the Boron clusters. In this work, we shown that, with the deployment of a novel computational approach that incorporates density functional theory (DFT) into a guided global optimization search algorithm based on basin-hopping, it is possible to directly locate the local minima of small Boron clusters in the PES at the DFT level. The ground-state structures search algorithm as proposed in this work is initiated randomly and needs not a priori symmetry constraint artificially imposed throughout the search process. Small sized Boron clusters so obtained compare well to the results obtained by similar calculations in the literature. The electronic properties of each structures obtained are calculated within the DFT framework.

  16. Guided basin-hopping search of small boron clusters with density functional theory

    International Nuclear Information System (INIS)

    Ng, Wei Chun; Yoon, Tiem Leong; Lim, Thong Leng

    2015-01-01

    The search for the ground state structures of Boron clusters has been a difficult computational task due to the unique metalloid nature of Boron atom. Previous research works had overcome the problem in the search of the Boron ground-state structures by adding symmetry constraints prior to the process of locating the local minima in the potential energy surface (PES) of the Boron clusters. In this work, we shown that, with the deployment of a novel computational approach that incorporates density functional theory (DFT) into a guided global optimization search algorithm based on basin-hopping, it is possible to directly locate the local minima of small Boron clusters in the PES at the DFT level. The ground-state structures search algorithm as proposed in this work is initiated randomly and needs not a priori symmetry constraint artificially imposed throughout the search process. Small sized Boron clusters so obtained compare well to the results obtained by similar calculations in the literature. The electronic properties of each structures obtained are calculated within the DFT framework

  17. Searches for Fourth Generation, Vector-like Quarks and ttbar Resonances with the ATLAS Detector

    CERN Document Server

    Nektarijevic, S

    2013-01-01

    The LHC operation at the high center of mass energies has opened the insight into the potential production of exotic heavy particles. A summary of the searches for the heavy quarks and the heavy bosons decaying into the top-antitop pairs ($t\\bar{t}$ resonances) with $14.3~\\rm{fb^{-1}}$ of the ATLAS detector data at $\\sqrt{s} =8~\\rm{TeV}$ is presented here. The searches for heavy quarks are performed in frameworks of the chiral fourth generation and vector-like quarks. One of the searches is also sensitive to the production of four top quarks and positively-charged top quark pairs. The searches for the $t\\bar{t}$ resonances rely on the narrow width topcolor leptophobic $Z'$ and broad width Kaluza-Klein gluon as bench mark.

  18. Brassinosteroid-Induced Transcriptional Repression and Dephosphorylation-Dependent Protein Degradation Negatively Regulate BIN2-Interacting AIF2 (a BR Signaling-Negative Regulator) bHLH Transcription Factor.

    Science.gov (United States)

    Kim, Yoon; Song, Ji-Hye; Park, Seon-U; Jeong, You-Seung; Kim, Soo-Hwan

    2017-02-01

    Brassinosteroids (BRs) are plant polyhydroxy-steroids that play important roles in plant growth and development via extensive signal integration through direct interactions between regulatory components of different signaling pathways. Recent studies have shown that diverse helix-loop-helix/basic helix-loop-helix (HLH/bHLH) family proteins are actively involved in control of BR signaling pathways and interact with other signaling pathways. In this study, we show that ATBS1-INTERACTING FACTOR 2 (AIF2), a nuclear-localized atypical bHLH transcription factor, specifically interacts with BRASSINOSTEROID-INSENSITIVE 2 (BIN2) among other BR signaling molecules. Overexpression of AIF2 down-regulated transcript expression of growth-promoting genes, thus resulting in retardation of growth. AIF2 renders plants hyposensitive to BR-induced root growth inhibition, but shows little effects on BR-promoted hypocotyl elongation. Notably, AIF2 was dephosphorylated by BR, and the dephosphorylated AIF2 was subject to proteasome-mediated degradation. AIF2 degradation was greatly induced by BR and ABA, but relatively slightly by other hormones such as auxin, gibberellin, cytokinin and ethylene. Moreover, AIF2 transcription was significantly suppressed by a BRI1/BZR1-mediated BR signaling pathway through a direct binding of BRASSINAZOLE RESISTANT 1 (BZR1) to the BR response element (BRRE) region of the AIF2 promoter. In conclusion, our study suggests that BIN2-driven AIF2 phosphorylation could augment the BIN2/AIF2-mediated negative circuit of BR signaling pathways, and the BR-induced transcriptional repression and protein degradation negatively regulate AIF2 transcription factor, reinforcing the BZR1/BES1-mediated positive BR signaling pathway. © The Author 2017. Published by Oxford University Press on behalf of Japanese Society of Plant Physiologists. All rights reserved. For permissions, please email: journals.permissions@oup.com.

  19. Search for Supersymmetric Particles with the OPAL Detector at LEP2

    CERN Document Server

    Kanaya, N

    A search of Supersymmetric particles was performed using the data collected in 1999 and 2000 by the Opal detector at the LEP2 e+e- collider. The center-of-mass energies ranged from 192 GeV to 209 GeV, and the data analyzed correspond to an integrated luminosity of 432 pb-1. Supersymmetric models permit a large number of different experimental final states which should all be investigated. The search presented here is sensitive to final states with photons plus additional detector activity with missing energy. these topologies are characteristic of events expected in Gauge-Mediated Supersymmetry Breaking (GMSB) models. No significant evidence for their existence is observed. Finally, using various search results at centre-of-mass energy of 189 GeV, constraints on the parameters have been given within the framework of the minimal GMSB model.

  20. Optimal Noise Enhanced Signal Detection in a Unified Framework

    Directory of Open Access Journals (Sweden)

    Ting Yang

    2016-06-01

    Full Text Available In this paper, a new framework for variable detectors is formulated in order to solve different noise enhanced signal detection optimal problems, where six different disjoint sets of detector and discrete vector pairs are defined according to the two inequality-constraints on detection and false-alarm probabilities. Then theorems and algorithms constructed based on the new framework are presented to search the optimal noise enhanced solutions to maximize the relative improvements of the detection and the false-alarm probabilities, respectively. Further, the optimal noise enhanced solution of the maximum overall improvement is obtained based on the new framework and the relationship among the three maximums is presented. In addition, the sufficient conditions for improvability or non-improvability under the two certain constraints are given. Finally, numerous examples are presented to illustrate the theoretical results and the proofs of the main theorems are given in the Appendix.

  1. The Search Performance Evaluation and Prediction in Exploratory Search

    OpenAIRE

    LIU, FEI

    2016-01-01

    The exploratory search for complex search tasks requires an effective search behavior model to evaluate and predict user search performance. Few studies have investigated the relationship between user search behavior and search performance in exploratory search. This research adopts a mixed approach combining search system development, user search experiment, search query log analysis, and multivariate regression analysis to resolve the knowledge gap. Through this study, it is shown that expl...

  2. Ray Next-Event Estimator Transport of Primary and Secondary Gamma Rays

    Science.gov (United States)

    2011-03-01

    McGraw-Hill. Choppin, G. R., Liljenzin, J.-O., & Rydberg, J. (2002). Radiochemistry and Nuclear Chemistry (3rd ed.). Woburn, MA: Butterworth- Heinemann ...time-energy bins. Any performance enhancements (maybe parallel searching?) to the search routines decrease estimator computational time

  3. Dialysis search filters for PubMed, Ovid MEDLINE, and Embase databases.

    Science.gov (United States)

    Iansavichus, Arthur V; Haynes, R Brian; Lee, Christopher W C; Wilczynski, Nancy L; McKibbon, Ann; Shariff, Salimah Z; Blake, Peter G; Lindsay, Robert M; Garg, Amit X

    2012-10-01

    Physicians frequently search bibliographic databases, such as MEDLINE via PubMed, for best evidence for patient care. The objective of this study was to develop and test search filters to help physicians efficiently retrieve literature related to dialysis (hemodialysis or peritoneal dialysis) from all other articles indexed in PubMed, Ovid MEDLINE, and Embase. A diagnostic test assessment framework was used to develop and test robust dialysis filters. The reference standard was a manual review of the full texts of 22,992 articles from 39 journals to determine whether each article contained dialysis information. Next, 1,623,728 unique search filters were developed, and their ability to retrieve relevant articles was evaluated. The high-performance dialysis filters consisted of up to 65 search terms in combination. These terms included the words "dialy" (truncated), "uremic," "catheters," and "renal transplant wait list." These filters reached peak sensitivities of 98.6% and specificities of 98.5%. The filters' performance remained robust in an independent validation subset of articles. These empirically derived and validated high-performance search filters should enable physicians to effectively retrieve dialysis information from PubMed, Ovid MEDLINE, and Embase.

  4. Search for t-Channel Single Top Quark Production in p$\\bar{p}$ Collisions at 1.96 TeV

    Energy Technology Data Exchange (ETDEWEB)

    Perea, Philip Michael [Univ. of California, Riverside, CA (United States)

    2006-06-01

    I have performed a search for t-channel single top quark production in p$\\bar{p}$ single number sub collisions at 1.96 TeV on a 366 pb-1 dataset collected with the D0 detector from 2002-2005. The analysis is restricted to the leptonic decay of the W boson from the top quark to an electron or muon, tq$\\bar{b}$ → lvlb q$\\bar{b}$ (l = e,μ). A powerful b-quark tagging algorithm derived from neural networks is used to identify b jets and significantly reduce background. I further use neural networks to discriminate signal from background, and apply a binned likelihood calculation to the neural network output distributions to derive the final limits. No direct observation of single top quark production has been made, and I report expected/measured 95% confidence level limits of 3.5/8.0 pb.

  5. Versatility of PEEK as a fixed partial denture framework.

    Science.gov (United States)

    Sinha, Nikita; Gupta, Nidhi; Reddy, K Mahendranadh; Shastry, Y M

    2017-01-01

    Materials used for fixed partial denture (FPD) frameworks have had properties of excellent strength, durability, and biocompatibility. Some of the materials which have been used till date include alloys, ceramics, and high-performance polymers such as zirconia, Ni-Cr, lithium disilicate, and so on. All these, though excellent, have their advantages and disadvantages. Hence, the search has always been on for a better material. One such material, which has made its foray into dentistry in the recent times, is polyetheretherketone (PEEK). It is a semicrystalline thermoplastic material. PEEK has an excellent chemical resistance and mechanical properties that are retained at high temperatures. The versatility of PEEK as a dental material for FPD framework was evaluated in this case report.

  6. OpenDrift v1.0: a generic framework for trajectory modelling

    Directory of Open Access Journals (Sweden)

    K.-F. Dagestad

    2018-04-01

    Full Text Available OpenDrift is an open-source Python-based framework for Lagrangian particle modelling under development at the Norwegian Meteorological Institute with contributions from the wider scientific community. The framework is highly generic and modular, and is designed to be used for any type of drift calculations in the ocean or atmosphere. A specific module within the OpenDrift framework corresponds to a Lagrangian particle model in the traditional sense. A number of modules have already been developed, including an oil drift module, a stochastic search-and-rescue module, a pelagic egg module, and a basic module for atmospheric drift. The framework allows for the ingestion of an unspecified number of forcing fields (scalar and vectorial from various sources, including Eulerian ocean, atmosphere and wave models, but also measurements or a priori values for the same variables. A basic backtracking mechanism is inherent, using sign reversal of the total displacement vector and negative time stepping. OpenDrift is fast and simple to set up and use on Linux, Mac and Windows environments, and can be used with minimal or no Python experience. It is designed for flexibility, and researchers may easily adapt or write modules for their specific purpose. OpenDrift is also designed for performance, and simulations with millions of particles may be performed on a laptop. Further, OpenDrift is designed for robustness and is in daily operational use for emergency preparedness modelling (oil drift, search and rescue, and drifting ships at the Norwegian Meteorological Institute.

  7. Quark-gluon plasma searches: today and tomorrow

    International Nuclear Information System (INIS)

    Geist, W.M.

    1991-01-01

    Selected recent data from ion collisions at high energy are discussed in the frame-work of Quark-Gluon Plasma (QGP) searches. The purpose of these experiments is to measure the volume where a high temperature QGP may have been formed, determine its characteristic temperature, verify chemical equilibrium, establish deconfinement of this phase of matter, and/or find anything that differs from natural extrapolations from pp and pA collisions. Refined methods and new theoretical ideas for future experiments with heavier beams and/or at higher energies are briefly outlined. (G.P.) 49 refs., 28 figs

  8. Searches for BSM Higgs Bosons with ATLAS

    CERN Document Server

    Navarro, Gabriela; The ATLAS collaboration

    2015-01-01

    The discovery of a Higgs-like boson with a mass of about 125GeV has prompted the question of whether or not this particle is part of a much larger and more complex Higgs sector than that envisioned in the Standard Model. In this talk, the current results from the ATLAS Experiment regarding Beyond-the-Standard Model (BSM) Higgs hypothesis tests are outlined. Searches for additional Higgs bosons are presented and interpreted in well-motivated BSM Higgs frameworks, such as two-Higgs-doublet Models and the Minimal Supersymmetric Standard Model.

  9. One visual search, many memory searches: An eye-tracking investigation of hybrid search.

    Science.gov (United States)

    Drew, Trafton; Boettcher, Sage E P; Wolfe, Jeremy M

    2017-09-01

    Suppose you go to the supermarket with a shopping list of 10 items held in memory. Your shopping expedition can be seen as a combination of visual search and memory search. This is known as "hybrid search." There is a growing interest in understanding how hybrid search tasks are accomplished. We used eye tracking to examine how manipulating the number of possible targets (the memory set size [MSS]) changes how observers (Os) search. We found that dwell time on each distractor increased with MSS, suggesting a memory search was being executed each time a new distractor was fixated. Meanwhile, although the rate of refixation increased with MSS, it was not nearly enough to suggest a strategy that involves repeatedly searching visual space for subgroups of the target set. These data provide a clear demonstration that hybrid search tasks are carried out via a "one visual search, many memory searches" heuristic in which Os examine items in the visual array once with a very low rate of refixations. For each item selected, Os activate a memory search that produces logarithmic response time increases with increased MSS. Furthermore, the percentage of distractors fixated was strongly modulated by the MSS: More items in the MSS led to a higher percentage of fixated distractors. Searching for more potential targets appears to significantly alter how Os approach the task, ultimately resulting in more eye movements and longer response times.

  10. Using the Knowledge to Action Framework in practice: a citation analysis and systematic review.

    Science.gov (United States)

    Field, Becky; Booth, Andrew; Ilott, Irene; Gerrish, Kate

    2014-11-23

    Conceptual frameworks are recommended as a way of applying theory to enhance implementation efforts. The Knowledge to Action (KTA) Framework was developed in Canada by Graham and colleagues in the 2000s, following a review of 31 planned action theories. The framework has two components: Knowledge Creation and an Action Cycle, each of which comprises multiple phases. This review sought to answer two questions: 'Is the KTA Framework used in practice? And if so, how?' This study is a citation analysis and systematic review. The index citation for the original paper was identified on three databases-Web of Science, Scopus and Google Scholar-with the facility for citation searching. Limitations of English language and year of publication 2006-June 2013 were set. A taxonomy categorising the continuum of usage was developed. Only studies applying the framework to implementation projects were included. Data were extracted and mapped against each phase of the framework for studies where it was integral to the implementation project. The citation search yielded 1,787 records. A total of 1,057 titles and abstracts were screened. One hundred and forty-six studies described usage to varying degrees, ranging from referenced to integrated. In ten studies, the KTA Framework was integral to the design, delivery and evaluation of the implementation activities. All ten described using the Action Cycle and seven referred to Knowledge Creation. The KTA Framework was enacted in different health care and academic settings with projects targeted at patients, the public, and nursing and allied health professionals. The KTA Framework is being used in practice with varying degrees of completeness. It is frequently cited, with usage ranging from simple attribution via a reference, through informing planning, to making an intellectual contribution. When the framework was integral to knowledge translation, it guided action in idiosyncratic ways and there was theory fidelity. Prevailing wisdom

  11. GLPP: A Game-Based Location Privacy-Preserving Framework in Account Linked Mixed Location-Based Services

    Directory of Open Access Journals (Sweden)

    Zhuo Ma

    2018-01-01

    Full Text Available In Location-Based Services (LBSs platforms, such as Foursquare and Swarm, the submitted position for a share or search leads to the exposure of users’ activities. Additionally, the cross-platform account linkage could aggravate this exposure, as the fusion of users’ information can enhance inference attacks on users’ next submitted location. Hence, in this paper, we propose GLPP, a personalized and continuous location privacy-preserving framework in account linked platforms with different LBSs (i.e., search-based LBSs and share-based LBSs. The key point of GLPP is to obfuscate every location submitted in search-based LBSs so as to defend dynamic inference attacks. Specifically, first, possible inference attacks are listed through user behavioral analysis. Second, for each specific attack, an obfuscation model is proposed to minimize location privacy leakage under a given location distortion, which ensures submitted locations’ utility for search-based LBSs. Third, for dynamic attacks, a framework based on zero-sum game is adopted to joint specific obfuscation above and minimize the location privacy leakage to a balanced point. Experiments on real dataset prove the effectiveness of our proposed attacks in Accuracy, Certainty, and Correctness and, meanwhile, also show the performance of our preserving solution in defense of attacks and guarantee of location utility.

  12. Search for Scalar Leptons and Scalar Quarks at LEP

    CERN Document Server

    Achard, P.; Aguilar-Benitez, M.; Alcaraz, J.; Alemanni, G.; Allaby, J.; Aloisio, A.; Alviggi, M.G.; Anderhub, H.; Andreev, Valery P.; Anselmo, F.; Arefev, A.; Azemoon, T.; Aziz, T.; Bagnaia, P.; Bajo, A.; Baksay, G.; Baksay, L.; Baldew, S.V.; Banerjee, S.; Barczyk, A.; Barillere, R.; Bartalini, P.; Basile, M.; Batalova, N.; Battiston, R.; Bay, A.; Becattini, F.; Becker, U.; Behner, F.; Bellucci, L.; Berbeco, R.; Berdugo, J.; Berges, P.; Bertucci, B.; Betev, B.L.; Biasini, M.; Biglietti, M.; Biland, A.; Blaising, J.J.; Blyth, S.C.; Bobbink, G.J.; Bohm, A.; Boldizsar, L.; Borgia, B.; Bottai, S.; Bourilkov, D.; Bourquin, M.; Braccini, S.; Branson, J.G.; Brochu, F.; Burger, J.D.; Burger, W.J.; Cai, X.D.; Capell, M.; Cara Romeo, G.; Carlino, G.; Cartacci, A.; Casaus, J.; Cavallari, F.; Cavallo, N.; Cecchi, C.; Cerrada, M.; Chamizo, M.; Chang, Y.H.; Chemarin, M.; Chen, A.; Chen, G.; Chen, G.M.; Chen, H.F.; Chen, H.S.; Chiefari, G.; Cifarelli, L.; Cindolo, F.; Clare, I.; Clare, R.; Coignet, G.; Colino, N.; Costantini, S.; de la Cruz, B.; Cucciarelli, S.; van Dalen, J.A.; de Asmundis, R.; Deglon, P.; Debreczeni, J.; Degre, A.; Dehmelt, K.; Deiters, K.; della Volpe, D.; Delmeire, E.; Denes, P.; DeNotaristefani, F.; De Salvo, A.; Diemoz, M.; Dierckxsens, M.; Dionisi, C.; Dittmar, M.; Doria, A.; Dova, M.T.; Duchesneau, D.; Duda, M.; Echenard, B.; Eline, A.; El Hage, A.; El Mamouni, H.; Engler, A.; Eppling, F.J.; Extermann, P.; Falagan, M.A.; Falciano, S.; Favara, A.; Fay, J.; Fedin, O.; Felcini, M.; Ferguson, T.; Fesefeldt, H.; Fiandrini, E.; Field, J.H.; Filthaut, F.; Fisher, P.H.; Fisher, W.; Fisk, I.; Forconi, G.; Freudenreich, K.; Furetta, C.; Galaktionov, Iouri; Ganguli, S.N.; Garcia-Abia, Pablo; Gataullin, M.; Gentile, S.; Giagu, S.; Gong, Z.F.; Grenier, Gerald Jean; Grimm, O.; Gruenewald, M.W.; Guida, M.; van Gulik, R.; Gupta, V.K.; Gurtu, A.; Gutay, L.J.; Haas, D.; Hatzifotiadou, D.; Hebbeker, T.; Herve, Alain; Hirschfelder, J.; Hofer, H.; Hohlmann, M.; Holzner, G.; Hou, S.R.; Hu, Y.; Jin, B.N.; Jones, Lawrence W.; de Jong, P.; Josa-Mutuberria, I.; Kafer, D.; Kaur, M.; Kienzle-Focacci, M.N.; Kim, J.K.; Kirkby, Jasper; Kittel, W.; Klimentov, A.; Konig, A.C.; Kopal, M.; Koutsenko, V.; Kraber, M.; Kraemer, R.W.; Kruger, A.; Kunin, A.; Ladron de Guevara, P.; Laktineh, I.; Landi, G.; Lebeau, M.; Lebedev, A.; Lebrun, P.; Lecomte, P.; Lecoq, P.; Le Coultre, P.; Le Goff, J.M.; Leiste, R.; Levtchenko, M.; Levtchenko, P.; Li, C.; Likhoded, S.; Lin, C.H.; Lin, W.T.; Linde, F.L.; Lista, L.; Liu, Z.A.; Lohmann, W.; Longo, E.; Lu, Y.S.; Luci, C.; Luminari, L.; Lustermann, W.; Ma, W.G.; Malgeri, L.; Malinin, A.; Mana, C.; Mans, J.; Martin, J.P.; Marzano, F.; Mazumdar, K.; McNeil, R.R.; Mele, S.; Merola, L.; Meschini, M.; Metzger, W.J.; Mihul, A.; Milcent, H.; Mirabelli, G.; Mnich, J.; Mohanty, G.B.; Muanza, G.S.; Muijs, A.J.M.; Musicar, B.; Musy, M.; Nagy, S.; Natale, S.; Napolitano, M.; Nessi-Tedaldi, F.; Newman, H.; Nisati, A.; Novak, T.; Kluge, Hannelies; Ofierzynski, R.; Organtini, G.; Pal, I.; Palomares, C.; Paolucci, P.; Paramatti, R.; Passaleva, G.; Patricelli, S.; Paul, Thomas Cantzon; Pauluzzi, M.; Paus, C.; Pauss, F.; Pedace, M.; Pensotti, S.; Perret-Gallix, D.; Petersen, B.; Piccolo, D.; Pierella, F.; Pioppi, M.; Piroue, P.A.; Pistolesi, E.; Plyaskin, V.; Pohl, M.; Pojidaev, V.; Pothier, J.; Prokofev, D.; Quartieri, J.; Rahal-Callot, G.; Rahaman, Mohammad Azizur; Raics, P.; Raja, N.; Ramelli, R.; Rancoita, P.G.; Ranieri, R.; Raspereza, A.; Razis, P.; Ren, D.; Rescigno, M.; Reucroft, S.; Riemann, S.; Riles, Keith; Roe, B.P.; Romero, L.; Rosca, A.; Rosier-Lees, S.; Roth, Stefan; Rosenbleck, C.; Roux, B.; Rubio, J.A.; Ruggiero, G.; Rykaczewski, H.; Sakharov, A.; Saremi, S.; Sarkar, S.; Salicio, J.; Sanchez, E.; Schafer, C.; Schegelsky, V.; Schopper, H.; Schotanus, D.J.; Sciacca, C.; Servoli, L.; Shevchenko, S.; Shivarov, N.; Shoutko, V.; Shumilov, E.; Shvorob, A.; Son, D.; Souga, C.; Spillantini, P.; Steuer, M.; Stickland, D.P.; Stoyanov, B.; Straessner, A.; Sudhakar, K.; Sultanov, G.; Sun, L.Z.; Sushkov, S.; Suter, H.; Swain, J.D.; Szillasi, Z.; Tang, X.W.; Tarjan, P.; Tauscher, L.; Taylor, L.; Tellili, B.; Teyssier, D.; Timmermans, Charles; Ting, Samuel C.C.; Ting, S.M.; Tonwar, S.C.; Toth, J.; Tully, C.; Tung, K.L.; Ulbricht, J.; Valente, E.; Van de Walle, R.T.; Vasquez, R.; Veszpremi, V.; Vesztergombi, G.; Vetlitsky, I.; Vicinanza, D.; Viertel, G.; Villa, S.; Vivargent, M.; Vlachos, S.; Vodopianov, I.; Vogel, H.; Vogt, H.; Vorobev, I.; Vorobyov, A.A.; Wadhwa, M.; Wang, Q.; Wang, X.L.; Wang, Z.M.; Weber, M.; Wienemann, P.; Wilkens, H.; Wynhoff, S.; Xia, L.; Xu, Z.Z.; Yamamoto, J.; Yang, B.Z.; Yang, C.G.; Yang, H.J.; Yang, M.; Yeh, S.C.; Zalite, A.; Zalite, Yu.; Zhang, Z.P.; Zhao, J.; Zhu, G.Y.; Zhu, R.Y.; Zhuang, H.L.; Zichichi, A.; Zimmermann, B.; Zoller, M.

    2004-01-01

    Scalar partners of quarks and leptons, predicted in supersymmetric models, are searched for in e^+e^- collisions at centre-of-mass energies between 192GeV and 209GeV at LEP. No evidence for any such particle is found in a data sample of 450 pb^-1. Upper limits on their production cross sections are set and lower limits on their masses are derived in the framework of the Minimal Supersymmetric Standard Model.

  13. Prior-Based Quantization Bin Matching for Cloud Storage of JPEG Images.

    Science.gov (United States)

    Liu, Xianming; Cheung, Gene; Lin, Chia-Wen; Zhao, Debin; Gao, Wen

    2018-07-01

    Millions of user-generated images are uploaded to social media sites like Facebook daily, which translate to a large storage cost. However, there exists an asymmetry in upload and download data: only a fraction of the uploaded images are subsequently retrieved for viewing. In this paper, we propose a cloud storage system that reduces the storage cost of all uploaded JPEG photos, at the expense of a controlled increase in computation mainly during download of requested image subset. Specifically, the system first selectively re-encodes code blocks of uploaded JPEG images using coarser quantization parameters for smaller storage sizes. Then during download, the system exploits known signal priors-sparsity prior and graph-signal smoothness prior-for reverse mapping to recover original fine quantization bin indices, with either deterministic guarantee (lossless mode) or statistical guarantee (near-lossless mode). For fast reverse mapping, we use small dictionaries and sparse graphs that are tailored for specific clusters of similar blocks, which are classified via tree-structured vector quantizer. During image upload, cluster indices identifying the appropriate dictionaries and graphs for the re-quantized blocks are encoded as side information using a differential distributed source coding scheme to facilitate reverse mapping during image download. Experimental results show that our system can reap significant storage savings (up to 12.05%) at roughly the same image PSNR (within 0.18 dB).

  14. A Framework for Debugging Geoscience Projects in a High Performance Computing Environment

    Science.gov (United States)

    Baxter, C.; Matott, L.

    2012-12-01

    High performance computing (HPC) infrastructure has become ubiquitous in today's world with the emergence of commercial cloud computing and academic supercomputing centers. Teams of geoscientists, hydrologists and engineers can take advantage of this infrastructure to undertake large research projects - for example, linking one or more site-specific environmental models with soft computing algorithms, such as heuristic global search procedures, to perform parameter estimation and predictive uncertainty analysis, and/or design least-cost remediation systems. However, the size, complexity and distributed nature of these projects can make identifying failures in the associated numerical experiments using conventional ad-hoc approaches both time- consuming and ineffective. To address these problems a multi-tiered debugging framework has been developed. The framework allows for quickly isolating and remedying a number of potential experimental failures, including: failures in the HPC scheduler; bugs in the soft computing code; bugs in the modeling code; and permissions and access control errors. The utility of the framework is demonstrated via application to a series of over 200,000 numerical experiments involving a suite of 5 heuristic global search algorithms and 15 mathematical test functions serving as cheap analogues for the simulation-based optimization of pump-and-treat subsurface remediation systems.

  15. People, plants and health: a conceptual framework for assessing changes in medicinal plant consumption

    Directory of Open Access Journals (Sweden)

    Smith-Hall Carsten

    2012-11-01

    Full Text Available Abstract Background A large number of people in both developing and developed countries rely on medicinal plant products to maintain their health or treat illnesses. Available evidence suggests that medicinal plant consumption will remain stable or increase in the short to medium term. Knowledge on what factors determine medicinal plant consumption is, however, scattered across many disciplines, impeding, for example, systematic consideration of plant-based traditional medicine in national health care systems. The aim of the paper is to develop a conceptual framework for understanding medicinal plant consumption dynamics. Consumption is employed in the economic sense: use of medicinal plants by consumers or in the production of other goods. Methods PubMed and Web of Knowledge (formerly Web of Science were searched using a set of medicinal plant key terms (folk/peasant/rural/traditional/ethno/indigenous/CAM/herbal/botanical/phytotherapy; each search terms was combined with terms related to medicinal plant consumption dynamics (medicinal plants/health care/preference/trade/treatment seeking behavior/domestication/sustainability/conservation/urban/migration/climate change/policy/production systems. To eliminate studies not directly focused on medicinal plant consumption, searches were limited by a number of terms (chemistry/clinical/in vitro/antibacterial/dose/molecular/trial/efficacy/antimicrobial/alkaloid/bioactive/inhibit/antibody/purification/antioxidant/DNA/rat/aqueous. A total of 1940 references were identified; manual screening for relevance reduced this to 645 relevant documents. As the conceptual framework emerged inductively, additional targeted literature searches were undertaken on specific factors and link, bringing the final number of references to 737. Results The paper first defines the four main groups of medicinal plant users (1. Hunter-gatherers, 2. Farmers and pastoralists, 3. Urban and peri-urban people, 4. Entrepreneurs and

  16. People, plants and health: a conceptual framework for assessing changes in medicinal plant consumption.

    Science.gov (United States)

    Smith-Hall, Carsten; Larsen, Helle Overgaard; Pouliot, Mariève

    2012-11-13

    A large number of people in both developing and developed countries rely on medicinal plant products to maintain their health or treat illnesses. Available evidence suggests that medicinal plant consumption will remain stable or increase in the short to medium term. Knowledge on what factors determine medicinal plant consumption is, however, scattered across many disciplines, impeding, for example, systematic consideration of plant-based traditional medicine in national health care systems. The aim of the paper is to develop a conceptual framework for understanding medicinal plant consumption dynamics. Consumption is employed in the economic sense: use of medicinal plants by consumers or in the production of other goods. PubMed and Web of Knowledge (formerly Web of Science) were searched using a set of medicinal plant key terms (folk/peasant/rural/traditional/ethno/indigenous/CAM/herbal/botanical/phytotherapy); each search terms was combined with terms related to medicinal plant consumption dynamics (medicinal plants/health care/preference/trade/treatment seeking behavior/domestication/sustainability/conservation/urban/migration/climate change/policy/production systems). To eliminate studies not directly focused on medicinal plant consumption, searches were limited by a number of terms (chemistry/clinical/in vitro/antibacterial/dose/molecular/trial/efficacy/antimicrobial/alkaloid/bioactive/inhibit/antibody/purification/antioxidant/DNA/rat/aqueous). A total of 1940 references were identified; manual screening for relevance reduced this to 645 relevant documents. As the conceptual framework emerged inductively, additional targeted literature searches were undertaken on specific factors and link, bringing the final number of references to 737. The paper first defines the four main groups of medicinal plant users (1. Hunter-gatherers, 2. Farmers and pastoralists, 3. Urban and peri-urban people, 4. Entrepreneurs) and the three main types of benefits (consumer, producer

  17. A Flexible Computational Framework Using R and Map-Reduce for Permutation Tests of Massive Genetic Analysis of Complex Traits.

    Science.gov (United States)

    Mahjani, Behrang; Toor, Salman; Nettelblad, Carl; Holmgren, Sverker

    2017-01-01

    In quantitative trait locus (QTL) mapping significance of putative QTL is often determined using permutation testing. The computational needs to calculate the significance level are immense, 10 4 up to 10 8 or even more permutations can be needed. We have previously introduced the PruneDIRECT algorithm for multiple QTL scan with epistatic interactions. This algorithm has specific strengths for permutation testing. Here, we present a flexible, parallel computing framework for identifying multiple interacting QTL using the PruneDIRECT algorithm which uses the map-reduce model as implemented in Hadoop. The framework is implemented in R, a widely used software tool among geneticists. This enables users to rearrange algorithmic steps to adapt genetic models, search algorithms, and parallelization steps to their needs in a flexible way. Our work underlines the maturity of accessing distributed parallel computing for computationally demanding bioinformatics applications through building workflows within existing scientific environments. We investigate the PruneDIRECT algorithm, comparing its performance to exhaustive search and DIRECT algorithm using our framework on a public cloud resource. We find that PruneDIRECT is vastly superior for permutation testing, and perform 2 ×10 5 permutations for a 2D QTL problem in 15 hours, using 100 cloud processes. We show that our framework scales out almost linearly for a 3D QTL search.

  18. Genetic dissection of maize plant architecture with an ultra-high density bin map based on recombinant inbred lines.

    Science.gov (United States)

    Zhou, Zhiqiang; Zhang, Chaoshu; Zhou, Yu; Hao, Zhuanfang; Wang, Zhenhua; Zeng, Xing; Di, Hong; Li, Mingshun; Zhang, Degui; Yong, Hongjun; Zhang, Shihuang; Weng, Jianfeng; Li, Xinhai

    2016-03-03

    Plant architecture attributes, such as plant height, ear height, and internode number, have played an important role in the historical increases in grain yield, lodging resistance, and biomass in maize (Zea mays L.). Analyzing the genetic basis of variation in plant architecture using high density QTL mapping will be of benefit for the breeding of maize for many traits. However, the low density of molecular markers in existing genetic maps has limited the efficiency and accuracy of QTL mapping. Genotyping by sequencing (GBS) is an improved strategy for addressing a complex genome via next-generation sequencing technology. GBS has been a powerful tool for SNP discovery and high-density genetic map construction. The creation of ultra-high density genetic maps using large populations of advanced recombinant inbred lines (RILs) is an efficient way to identify QTL for complex agronomic traits. A set of 314 RILs derived from inbreds Ye478 and Qi319 were generated and subjected to GBS. A total of 137,699,000 reads with an average of 357,376 reads per individual RIL were generated, which is equivalent to approximately 0.07-fold coverage of the maize B73 RefGen_V3 genome for each individual RIL. A high-density genetic map was constructed using 4183 bin markers (100-Kb intervals with no recombination events). The total genetic distance covered by the linkage map was 1545.65 cM and the average distance between adjacent markers was 0.37 cM with a physical distance of about 0.51 Mb. Our results demonstrated a relatively high degree of collinearity between the genetic map and the B73 reference genome. The quality and accuracy of the bin map for QTL detection was verified by the mapping of a known gene, pericarp color 1 (P1), which controls the color of the cob, with a high LOD value of 80.78 on chromosome 1. Using this high-density bin map, 35 QTL affecting plant architecture, including 14 for plant height, 14 for ear height, and seven for internode number were detected

  19. Searches for signals of supersymmetry

    International Nuclear Information System (INIS)

    Grivaz, J.F.

    1993-04-01

    Direct searches for the Higgs bosons of the minimal supersymmetric extension of the Standard Model (MSSM) and for supersymmetric particles performed at high energy e + e - and pp-bar colliders are reviewed. Lower mass limits of 44 and 21 GeV/c 2 are obtained for the CP-even and CP-odd Higgs bosons, respectively. All supersymmetric particles but the lightest one are excluded at least up to 40 GeV/c 2 , in a model independent way except for neutralinos. Unless they are very light, gluinos are excluded up to 90 GeV/c 2 . The implications of these results within the MSSM framework are discussed. (author) 20 refs.; 6 figs

  20. SearchResultFinder: federated search made easy

    NARCIS (Netherlands)

    Trieschnigg, Rudolf Berend; Tjin-Kam-Jet, Kien; Hiemstra, Djoerd

    Building a federated search engine based on a large number existing web search engines is a challenge: implementing the programming interface (API) for each search engine is an exacting and time-consuming job. In this demonstration we present SearchResultFinder, a browser plugin which speeds up

  1. Comparison of vibrational noise, between thermal power station (T.P.S.) Jamshoro and thermal power plant (T.P.P.) Pakistan Steel Bin Qasim Karachi

    International Nuclear Information System (INIS)

    Zaheer-ud-Din Memon

    2003-01-01

    Vibrational Noise is one of the major environmental problems in Industrial Plants. The Noise study has been under taken in (Japanese Unit) Thermal Power Station (TPS) Jamshoro, which generates 250 MW since Jan: 1990 and Russian Unit Thermal Power Plant (TPP) Pak Steel Bin Qasim Karachi, generates 165 MW since 1984. The prevailing Noise has been recorded in detail; at Basement area feed pumps, Turbines, Boilers F.D.F, I.D.F and Compressor houses. Comparing these two Plants, the Noise Level found more Intensive i.e. 97- 114 dB(A) at TPP Pak Steel Bin Qasim as against 91.4 -96.3 dB(A) at TPS Jamshoro, which was even higher one in the light of ISO and other National Standards. In the light of permissible Occupational Noise exposure limits, as allowed by the ISO and other National Standards, some recommendations have been made to provide safety measures for workers against high level noise health hazards like head ache, hearing problem, irritation, accidents at work, tension, disturbance to work and so many psychological effects, along with guidelines to improve the efficiency of the plants. (author)

  2. A predictive framework for evaluating models of semantic organization in free recall

    Science.gov (United States)

    Morton, Neal W; Polyn, Sean M.

    2016-01-01

    Research in free recall has demonstrated that semantic associations reliably influence the organization of search through episodic memory. However, the specific structure of these associations and the mechanisms by which they influence memory search remain unclear. We introduce a likelihood-based model-comparison technique, which embeds a model of semantic structure within the context maintenance and retrieval (CMR) model of human memory search. Within this framework, model variants are evaluated in terms of their ability to predict the specific sequence in which items are recalled. We compare three models of semantic structure, latent semantic analysis (LSA), global vectors (GloVe), and word association spaces (WAS), and find that models using WAS have the greatest predictive power. Furthermore, we find evidence that semantic and temporal organization is driven by distinct item and context cues, rather than a single context cue. This finding provides important constraint for theories of memory search. PMID:28331243

  3. Personality moderates the links of social identity with work motivation and job searching.

    Science.gov (United States)

    Baay, Pieter E; van Aken, Marcel A G; van der Lippe, Tanja; de Ridder, Denise T D

    2014-01-01

    Work motivation is critical for successful school-to-work transitions, but little is known about its determinants among labor market entrants. Applying a social identity framework, we examined whether work motivation and job searching are social-contextually determined. We expected that some job seekers are more sensitive to contextual influence, depending on their personality. Mediation analyses on 591 Dutch vocational training students indicate that the perception of more positive work norms in someone's social context was related to higher levels of intrinsic motivation, which in turn predicted higher preparatory job search behavior and job search intentions. Multi-group analysis shows that perceived work norms more strongly predict work motivation among overcontrollers compared to resilients and undercontrollers. In conclusion, work motivation and job searching appear contextually determined: especially among those sensitive to contextual influence, people seem to work when they believe that is what people like them do.

  4. Search for scalar quarks in $e^{+}e^{-}$ collisions at LEP II

    CERN Document Server

    Sushkov, Serge; Hebbeker, T; Lohse, T

    2003-01-01

    This thesis is devoted to searches for the scalar top and the scalar bottom quarks within the framework of the Minimal Supersymmetric Standard Model (MSSM) with the assumption of R-parity conservation. Searches for the following decay modes of the stop quark have been performed: stop -> c neutralino_1, stop -> b l sneutrino, (where l is either electron, muon or tau-lepton with equal probabilities) and stop -> b tau sneutrino (where only the tau-lepton is considered). In addition, a three body decay stop -> b W neutralino_1 has been searched for in the allowed mass region of M_stop > M_b + M_W + M_neutralino1 >= 86 GeV. For the sbottom quark the decay sbottom -> b neutralino_1 was considered. Each of these decay modes was considered independently assuming a branching ratio of 100 %. For this search, the experimental data of electron-positron collisions at center-of-mass energies (c.m.s.) in the range of 202-208 GeV have been used. These data were collected in the year 2000 by the L3 detector at the Large Elect...

  5. One lens missing? Clarifying the clinical microsystem framework with learning theories.

    Science.gov (United States)

    Norman, Ann-Charlott; Fritzen, Lena; Fridh, Marianne Lindblad

    2013-01-01

    The clinical microsystem (CMS) approach is widely used and is perceived as helpful in practice but, we ask the question: "Is its learning potential sufficiently utilized?" To scrutinize aspects of learning within the CMS framework and to clarify the learning aspects the framework includes and thereby support the framework with the enhanced learning perspective that becomes visible. Literature on the CMS framework was systematically searched and selected using inclusion criteria. An analytical tool was constructed in the form of a theoretical lens that was used to clarify learning aspects that are associated with the framework. The analysis revealed 3 learning aspects: (1) The CMS framework describes individual and social learning but not how to adapt learning strategies for purposes of change. (2) The metaphorical language of how to reach a holistic health care system for each patient has developed over time but can still be improved by naming social interactions to transcend organizational boundaries. (3) Power structures are recognized but not as a characteristic that restricts learning due to asymmetric communication. The "lens" perspective reveals new meanings to learning that enhance our understanding of health care as a social system and provides new practical learning strategies.

  6. From Schrцdinger's equation to the quantum search algorithm£

    Indian Academy of Sciences (India)

    Also the framework was simple and general and could be extended to ... It is unusual to write a paper listing the steps that led to a result after the result itself ... the quantum search algorithm – it is by no means a comprehensive review of quantum ..... D, as defined in the previous section, is no longer unitary for large ε.

  7. A framework for automatic information quality ranking of diabetes websites.

    Science.gov (United States)

    Belen Sağlam, Rahime; Taskaya Temizel, Tugba

    2015-01-01

    Objective: When searching for particular medical information on the internet the challenge lies in distinguishing the websites that are relevant to the topic, and contain accurate information. In this article, we propose a framework that automatically identifies and ranks diabetes websites according to their relevance and information quality based on the website content. Design: The proposed framework ranks diabetes websites according to their content quality, relevance and evidence based medicine. The framework combines information retrieval techniques with a lexical resource based on Sentiwordnet making it possible to work with biased and untrusted websites while, at the same time, ensuring the content relevance. Measurement: The evaluation measurements used were Pearson-correlation, true positives, false positives and accuracy. We tested the framework with a benchmark data set consisting of 55 websites with varying degrees of information quality problems. Results: The proposed framework gives good results that are comparable with the non-automated information quality measuring approaches in the literature. The correlation between the results of the proposed automated framework and ground-truth is 0.68 on an average with p < 0.001 which is greater than the other proposed automated methods in the literature (r score in average is 0.33).

  8. A Framework for Evaluating Advanced Search Concepts for Multiple Autonomous Underwater Vehicle (AUV) Mine Countermeasures (MCM)

    National Research Council Canada - National Science Library

    Gooding, Trent

    2001-01-01

    .... In recent years, autonomous underwater vehicles (AUV) have emerged as a viable technology for conducting underwater search, survey, and clearance operations in support of the mine countermeasures (MCM) mission...

  9. Search for gravitational waves associated with GRB 050915a using the Virgo detector

    NARCIS (Netherlands)

    Acernese, F.; Bauer, T.; Russo, G.; van den Brand, J.F.J.

    2008-01-01

    In the framework of the expected association between gamma-ray bursts and gravitational waves, we present results of an analysis aimed to search for a burst of gravitational waves in coincidence with gamma-ray burst 050915a. This was a long duration gamma-ray burst detected by Swift during September

  10. Anatomy and evolution of database search engines-a central component of mass spectrometry based proteomic workflows.

    Science.gov (United States)

    Verheggen, Kenneth; Raeder, Helge; Berven, Frode S; Martens, Lennart; Barsnes, Harald; Vaudel, Marc

    2017-09-13

    Sequence database search engines are bioinformatics algorithms that identify peptides from tandem mass spectra using a reference protein sequence database. Two decades of development, notably driven by advances in mass spectrometry, have provided scientists with more than 30 published search engines, each with its own properties. In this review, we present the common paradigm behind the different implementations, and its limitations for modern mass spectrometry datasets. We also detail how the search engines attempt to alleviate these limitations, and provide an overview of the different software frameworks available to the researcher. Finally, we highlight alternative approaches for the identification of proteomic mass spectrometry datasets, either as a replacement for, or as a complement to, sequence database search engines. © 2017 Wiley Periodicals, Inc.

  11. Conceptual framework for development of comprehensive e-health evaluation tool.

    Science.gov (United States)

    Khoja, Shariq; Durrani, Hammad; Scott, Richard E; Sajwani, Afroz; Piryani, Usha

    2013-01-01

    The main objective of this study was to develop an e-health evaluation tool based on a conceptual framework including relevant theories for evaluating use of technology in health programs. This article presents the development of an evaluation framework for e-health programs. The study was divided into three stages: Stage 1 involved a detailed literature search of different theories and concepts on evaluation of e-health, Stage 2 plotted e-health theories to identify relevant themes, and Stage 3 developed a matrix of evaluation themes and stages of e-health programs. The framework identifies and defines different stages of e-health programs and then applies evaluation theories to each of these stages for development of the evaluation tool. This framework builds on existing theories of health and technology evaluation and presents a conceptual framework for developing an e-health evaluation tool to examine and measure different factors that play a definite role in the success of e-health programs. The framework on the horizontal axis divides e-health into different stages of program implementation, while the vertical axis identifies different themes and areas of consideration for e-health evaluation. The framework helps understand various aspects of e-health programs and their impact that require evaluation at different stages of the life cycle. The study led to the development of a new and comprehensive e-health evaluation tool, named the Khoja-Durrani-Scott Framework for e-Health Evaluation.

  12. Optimizing Earth Data Search Ranking using Deep Learning and Real-time User Behaviour

    Science.gov (United States)

    Jiang, Y.; Yang, C. P.; Armstrong, E. M.; Huang, T.; Moroni, D. F.; McGibbney, L. J.; Greguska, F. R., III

    2017-12-01

    Finding Earth science data has been a challenging problem given both the quantity of data available and the heterogeneity of the data across a wide variety of domains. Current search engines in most geospatial data portals tend to induce end users to focus on one single data characteristic dimension (e.g., term frequency-inverse document frequency (TF-IDF) score, popularity, release date, etc.). This approach largely fails to take account of users' multidimensional preferences for geospatial data, and hence may likely result in a less than optimal user experience in discovering the most applicable dataset out of a vast range of available datasets. With users interacting with search engines, sufficient information is already hidden in the log files. Compared with explicit feedback data, information that can be derived/extracted from log files is virtually free and substantially more timely. In this dissertation, I propose an online deep learning framework that can quickly update the learning function based on real-time user clickstream data. The contributions of this framework include 1) a log processor that can ingest, process and create training data from web logs in a real-time manner; 2) a query understanding module to better interpret users' search intent using web log processing results and metadata; 3) a feature extractor that identifies ranking features representing users' multidimensional interests of geospatial data; and 4) a deep learning based ranking algorithm that can be trained incrementally using user behavior data. The search ranking results will be evaluated using precision at K and normalized discounted cumulative gain (NDCG).

  13. Open meta-search with OpenSearch: a case study

    OpenAIRE

    O'Riordan, Adrian P.

    2007-01-01

    The goal of this project was to demonstrate the possibilities of open source search engine and aggregation technology in a Web environment by building a meta-search engine which employs free open search engines and open protocols. In contrast many meta-search engines on the Internet use proprietary search systems. The search engines employed in this case study are all based on the OpenSearch protocol. OpenSearch-compliant systems support XML technologies such as RSS and Atom for aggregation a...

  14. Systematizing Web Search through a Meta-Cognitive, Systems-Based, Information Structuring Model (McSIS)

    Science.gov (United States)

    Abuhamdieh, Ayman H.; Harder, Joseph T.

    2015-01-01

    This paper proposes a meta-cognitive, systems-based, information structuring model (McSIS) to systematize online information search behavior based on literature review of information-seeking models. The General Systems Theory's (GST) prepositions serve as its framework. Factors influencing information-seekers, such as the individual learning…

  15. Image quality in thoracic 4D cone-beam CT: A sensitivity analysis of respiratory signal, binning method, reconstruction algorithm, and projection angular spacing

    OpenAIRE

    Shieh, Chun-Chien; Kipritidis, John; O’Brien, Ricky T.; Kuncic, Zdenka; Keall, Paul J.

    2014-01-01

    Purpose: Respiratory signal, binning method, and reconstruction algorithm are three major controllable factors affecting image quality in thoracic 4D cone-beam CT (4D-CBCT), which is widely used in image guided radiotherapy (IGRT). Previous studies have investigated each of these factors individually, but no integrated sensitivity analysis has been performed. In addition, projection angular spacing is also a key factor in reconstruction, but how it affects image quality is not obvious. An inv...

  16. Generic, Extensible, Configurable Push-Pull Framework for Large-Scale Science Missions

    Science.gov (United States)

    Foster, Brian M.; Chang, Albert Y.; Freeborn, Dana J.; Crichton, Daniel J.; Woollard, David M.; Mattmann, Chris A.

    2011-01-01

    The push-pull framework was developed in hopes that an infrastructure would be created that could literally connect to any given remote site, and (given a set of restrictions) download files from that remote site based on those restrictions. The Cataloging and Archiving Service (CAS) has recently been re-architected and re-factored in its canonical services, including file management, workflow management, and resource management. Additionally, a generic CAS Crawling Framework was built based on motivation from Apache s open-source search engine project called Nutch. Nutch is an Apache effort to provide search engine services (akin to Google), including crawling, parsing, content analysis, and indexing. It has produced several stable software releases, and is currently used in production services at companies such as Yahoo, and at NASA's Planetary Data System. The CAS Crawling Framework supports many of the Nutch Crawler's generic services, including metadata extraction, crawling, and ingestion. However, one service that was not ported over from Nutch is a generic protocol layer service that allows the Nutch crawler to obtain content using protocol plug-ins that download content using implementations of remote protocols, such as HTTP, FTP, WinNT file system, HTTPS, etc. Such a generic protocol layer would greatly aid in the CAS Crawling Framework, as the layer would allow the framework to generically obtain content (i.e., data products) from remote sites using protocols such as FTP and others. Augmented with this capability, the Orbiting Carbon Observatory (OCO) and NPP (NPOESS Preparatory Project) Sounder PEATE (Product Evaluation and Analysis Tools Elements) would be provided with an infrastructure to support generic FTP-based pull access to remote data products, obviating the need for any specialized software outside of the context of their existing process control systems. This extensible configurable framework was created in Java, and allows the use of

  17. Cyber Security Research Frameworks For Coevolutionary Network Defense

    Energy Technology Data Exchange (ETDEWEB)

    Rush, George D. [Missouri Univ. of Science and Technology, Rolla, MO (United States); Tauritz, Daniel Remy [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-12-03

    Several architectures have been created for developing and testing systems used in network security, but most are meant to provide a platform for running cyber security experiments as opposed to automating experiment processes. In the first paper, we propose a framework termed Distributed Cyber Security Automation Framework for Experiments (DCAFE) that enables experiment automation and control in a distributed environment. Predictive analysis of adversaries is another thorny issue in cyber security. Game theory can be used to mathematically analyze adversary models, but its scalability limitations restrict its use. Computational game theory allows us to scale classical game theory to larger, more complex systems. In the second paper, we propose a framework termed Coevolutionary Agent-based Network Defense Lightweight Event System (CANDLES) that can coevolve attacker and defender agent strategies and capabilities and evaluate potential solutions with a custom network defense simulation. The third paper is a continuation of the CANDLES project in which we rewrote key parts of the framework. Attackers and defenders have been redesigned to evolve pure strategy, and a new network security simulation is devised which specifies network architecture and adds a temporal aspect. We also add a hill climber algorithm to evaluate the search space and justify the use of a coevolutionary algorithm.

  18. In Search of Optimal Cognitive Diagnostic Model(s) for ESL Grammar Test Data

    Science.gov (United States)

    Yi, Yeon-Sook

    2017-01-01

    This study compares five cognitive diagnostic models in search of optimal one(s) for English as a Second Language grammar test data. Using a unified modeling framework that can represent specific models with proper constraints, the article first fit the full model (the log-linear cognitive diagnostic model, LCDM) and investigated which model…

  19. Assessing the impact of healthcare research: A systematic review of methodological frameworks.

    Directory of Open Access Journals (Sweden)

    Samantha Cruz Rivera

    2017-08-01

    Full Text Available Increasingly, researchers need to demonstrate the impact of their research to their sponsors, funders, and fellow academics. However, the most appropriate way of measuring the impact of healthcare research is subject to debate. We aimed to identify the existing methodological frameworks used to measure healthcare research impact and to summarise the common themes and metrics in an impact matrix.Two independent investigators systematically searched the Medical Literature Analysis and Retrieval System Online (MEDLINE, the Excerpta Medica Database (EMBASE, the Cumulative Index to Nursing and Allied Health Literature (CINAHL+, the Health Management Information Consortium, and the Journal of Research Evaluation from inception until May 2017 for publications that presented a methodological framework for research impact. We then summarised the common concepts and themes across methodological frameworks and identified the metrics used to evaluate differing forms of impact. Twenty-four unique methodological frameworks were identified, addressing 5 broad categories of impact: (1 'primary research-related impact', (2 'influence on policy making', (3 'health and health systems impact', (4 'health-related and societal impact', and (5 'broader economic impact'. These categories were subdivided into 16 common impact subgroups. Authors of the included publications proposed 80 different metrics aimed at measuring impact in these areas. The main limitation of the study was the potential exclusion of relevant articles, as a consequence of the poor indexing of the databases searched.The measurement of research impact is an essential exercise to help direct the allocation of limited research resources, to maximise research benefit, and to help minimise research waste. This review provides a collective summary of existing methodological frameworks for research impact, which funders may use to inform the measurement of research impact and researchers may use to inform

  20. Systematic search for very-high-energy gamma-ray emission from bow shocks of runaway stars

    Science.gov (United States)

    H.E.S.S. Collaboration; Abdalla, H.; Abramowski, A.; Aharonian, F.; Ait Benkhali, F.; Akhperjanian, A. G.; Andersson, T.; Angüner, E. O.; Arakawa, M.; Arrieta, M.; Aubert, P.; Backes, M.; Balzer, A.; Barnard, M.; Becherini, Y.; Becker Tjus, J.; Berge, D.; Bernhard, S.; Bernlöhr, K.; Blackwell, R.; Böttcher, M.; Boisson, C.; Bolmont, J.; Bordas, P.; Bregeon, J.; Brun, F.; Brun, P.; Bryan, M.; Büchele, M.; Bulik, T.; Capasso, M.; Carr, J.; Casanova, S.; Cerruti, M.; Chakraborty, N.; Chalme-Calvet, R.; Chaves, R. C. G.; Chen, A.; Chevalier, J.; Chrétien, M.; Coffaro, M.; Colafrancesco, S.; Cologna, G.; Condon, B.; Conrad, J.; Cui, Y.; Davids, I. D.; Decock, J.; Degrange, B.; Deil, C.; Devin, J.; deWilt, P.; Dirson, L.; Djannati-Ataï, A.; Domainko, W.; Donath, A.; Drury, L. O.'C.; Dutson, K.; Dyks, J.; Edwards, T.; Egberts, K.; Eger, P.; Ernenwein, J.-P.; Eschbach, S.; Farnier, C.; Fegan, S.; Fernandes, M. V.; Fiasson, A.; Fontaine, G.; Förster, A.; Funk, S.; Füßling, M.; Gabici, S.; Gajdus, M.; Gallant, Y. A.; Garrigoux, T.; Giavitto, G.; Giebels, B.; Glicenstein, J. F.; Gottschall, D.; Goyal, A.; Grondin, M.-H.; Hahn, J.; Haupt, M.; Hawkes, J.; Heinzelmann, G.; Henri, G.; Hermann, G.; Hervet, O.; Hinton, J. A.; Hofmann, W.; Hoischen, C.; Holler, M.; Horns, D.; Ivascenko, A.; Iwasaki, H.; Jacholkowska, A.; Jamrozy, M.; Janiak, M.; Jankowsky, D.; Jankowsky, F.; Jingo, M.; Jogler, T.; Jouvin, L.; Jung-Richardt, I.; Kastendieck, M. A.; Katarzyński, K.; Katsuragawa, M.; Katz, U.; Kerszberg, D.; Khangulyan, D.; Khélifi, B.; Kieffer, M.; King, J.; Klepser, S.; Klochkov, D.; Kluźniak, W.; Kolitzus, D.; Komin, Nu.; Kosack, K.; Krakau, S.; Kraus, M.; Krüger, P. P.; Laffon, H.; Lamanna, G.; Lau, J.; Lees, J.-P.; Lefaucheur, J.; Lefranc, V.; Lemière, A.; Lemoine-Goumard, M.; Lenain, J.-P.; Leser, E.; Lohse, T.; Lorentz, M.; Liu, R.; López-Coto, R.; Lypova, I.; Marandon, V.; Marcowith, A.; Mariaud, C.; Marx, R.; Maurin, G.; Maxted, N.; Mayer, M.; Meintjes, P. J.; Meyer, M.; Mitchell, A. M. W.; Moderski, R.; Mohamed, M.; Mohrmann, L.; Morå, K.; Moulin, E.; Murach, T.; Nakashima, S.; de Naurois, M.; Niederwanger, F.; Niemiec, J.; Oakes, L.; O'Brien, P.; Odaka, H.; Öttl, S.; Ohm, S.; Ostrowski, M.; Oya, I.; Padovani, M.; Panter, M.; Parsons, R. D.; Pekeur, N. W.; Pelletier, G.; Perennes, C.; Petrucci, P.-O.; Peyaud, B.; Piel, Q.; Pita, S.; Poon, H.; Prokhorov, D.; Prokoph, H.; Pühlhofer, G.; Punch, M.; Quirrenbach, A.; Raab, S.; Reimer, A.; Reimer, O.; Renaud, M.; de los Reyes, R.; Richter, S.; Rieger, F.; Romoli, C.; Rowell, G.; Rudak, B.; Rulten, C. B.; Sahakian, V.; Saito, S.; Salek, D.; Sanchez, D. A.; Santangelo, A.; Sasaki, M.; Schlickeiser, R.; Schüssler, F.; Schulz, A.; Schwanke, U.; Schwemmer, S.; Seglar-Arroyo, M.; Settimo, M.; Seyffert, A. S.; Shafi, N.; Shilon, I.; Simoni, R.; Sol, H.; Spanier, F.; Spengler, G.; Spies, F.; Stawarz, Ł.; Steenkamp, R.; Stegmann, C.; Stycz, K.; Sushch, I.; Takahashi, T.; Tavernet, J.-P.; Tavernier, T.; Taylor, A. M.; Terrier, R.; Tibaldo, L.; Tiziani, D.; Tluczykont, M.; Trichard, C.; Tsuji, N.; Tuffs, R.; Uchiyama, Y.; van der Walt, D. J.; van Eldik, C.; van Rensburg, C.; van Soelen, B.; Vasileiadis, G.; Veh, J.; Venter, C.; Viana, A.; Vincent, P.; Vink, J.; Voisin, F.; Völk, H. J.; Vuillaume, T.; Wadiasingh, Z.; Wagner, S. J.; Wagner, P.; Wagner, R. M.; White, R.; Wierzcholska, A.; Willmann, P.; Wörnlein, A.; Wouters, D.; Yang, R.; Zabalza, V.; Zaborov, D.; Zacharias, M.; Zanin, R.; Zdziarski, A. A.; Zech, A.; Zefi, F.; Ziegler, A.; Żywucka, N.

    2018-04-01

    Context. Runaway stars form bow shocks by ploughing through the interstellar medium at supersonic speeds and are promising sources of non-thermal emission of photons. One of these objects has been found to emit non-thermal radiation in the radio band. This triggered the development of theoretical models predicting non-thermal photons from radio up to very-high-energy (VHE, E ≥ 0.1 TeV) gamma rays. Subsequently, one bow shock was also detected in X-ray observations. However, the data did not allow discrimination between a hot thermal and a non-thermal origin. Further observations of different candidates at X-ray energies showed no evidence for emission at the position of the bow shocks either. A systematic search in the Fermi-LAT energy regime resulted in flux upper limits for 27 candidates listed in the E-BOSS catalogue. Aim. Here we perform the first systematic search for VHE gamma-ray emission from bow shocks of runaway stars. Methods: Using all available archival H.E.S.S. data we search for very-high-energy gamma-ray emission at the positions of bow shock candidates listed in the second E-BOSS catalogue release. Out of the 73 bow shock candidates in this catalogue, 32 have been observed with H.E.S.S. Results: None of the observed 32 bow shock candidates in this population study show significant emission in the H.E.S.S. energy range. Therefore, flux upper limits are calculated in five energy bins and the fraction of the kinetic wind power that is converted into VHE gamma rays is constrained. Conclusions: Emission from stellar bow shocks is not detected in the energy range between 0.14 and 18 TeV.The resulting upper limits constrain the level of VHE gamma-ray emission from these objects down to 0.1-1% of the kinetic wind energy.

  1. An interactive 3D framework for anatomical education

    OpenAIRE

    Vázquez Alcocer, Pere Pau; Götzelmann, Timo; Hartmann, Knut; Nürnberger, Andreas

    2008-01-01

    Object: This paper presents a 3D framework for Anatomy teaching. We are mainly concerned with the proper understanding of human anatomical 3D structures. Materials and methods: The main idea of our approach is taking an electronic book such as Henry Gray’s Anatomy of the human body, and a set of 3D models properly labeled, and constructing the correct linking that allows users to perform mutual searches between both media. Results: We implemented a system where learners can intera...

  2. A search for R-parity violating single sneutrino production at LEPII

    International Nuclear Information System (INIS)

    Coles, J.

    2000-01-01

    Supersymmetry has become one of the most accepted and theoretically interesting extensions to the Standard Model of particle physics, yet it has so far eluded discovery. For this reason there is a large amount of interest in direct particle searches looking for evidence of either R-parity conserving or R-parity violating signatures at high-energy colliders such as LEP. This work sets out to describe one such search, that for the R-parity violating process of resonant single sneutrino production. The R-parity violating searches are performed on ALEPH data taken at centre-of-mass energies 130 to 189 GeV. As no evidence for a signal is found, limits are set within the framework of a minimal supergravity model. The best upper limits obtained for the LLE-bar couplings λ 121 and λ 131 are shown to be better than 5 x 10 -4 at 95% C.L. These results provide a substantial improvement over existing low energy bounds. (author)

  3. A rectangle bin packing optimization approach to the signal scheduling problem in the FlexRay static segment

    Institute of Scientific and Technical Information of China (English)

    Rui ZHAO; Gui-he QIN; Jia-qiao LIU

    2016-01-01

    As FlexRay communication protocol is extensively used in distributed real-time applications on vehicles, signal scheduling in FlexRay network becomes a critical issue to ensure the safe and efficient operation of time-critical applications. In this study, we propose a rectangle bin packing optimization approach to schedule communication signals with timing constraints into the FlexRay static segment at minimum bandwidth cost. The proposed approach, which is based on integer linear program-ming (ILP), supports both the slot assignment mechanisms provided by the latest version of the FlexRay specification, namely, the single sender slot multiplexing, and multiple sender slot multiplexing mechanisms. Extensive experiments on a synthetic and an automotive X-by-wire system case study demonstrate that the proposed approach has a well optimized performance.

  4. Lithography hotspot discovery at 70nm DRAM 300mm fab: process window qualification using design base binning

    Science.gov (United States)

    Chen, Daniel; Chen, Damian; Yen, Ray; Cheng, Mingjen; Lan, Andy; Ghaskadvi, Rajesh

    2008-11-01

    Identifying hotspots--structures that limit the lithography process window--become increasingly important as the industry relies heavily on RET to print sub-wavelength designs. KLA-Tencor's patented Process Window Qualification (PWQ) methodology has been used for this purpose in various fabs. PWQ methodology has three key advantages (a) PWQ Layout--to obtain the best sensitivity (b) Design Based Binning--for pattern repeater analysis (c) Intelligent sampling--for the best DOI sampling rate. This paper evaluates two different analysis strategies for SEM review sampling successfully deployed at Inotera Memories, Inc. We propose a new approach combining the location repeater and pattern repeaters. Based on a recent case study the new sampling flow reduces the data analysis and sampling time from 6 hours to 1.5 hour maintaining maximum DOI sample rate.

  5. A unified framework of descent algorithms for nonlinear programs and variational inequalities

    International Nuclear Information System (INIS)

    Patriksson, M.

    1993-01-01

    We present a framework of algorithms for the solution of continuous optimization and variational inequality problems. In the general algorithm, a search direction finding auxiliary problems is obtained by replacing the original cost function with an approximating monotone cost function. The proposed framework encompasses algorithm classes presented earlier by Cohen, Dafermos, Migdalas, and Tseng, and includes numerous descent and successive approximation type methods, such as Newton methods, Jacobi and Gauss-Siedel type decomposition methods for problems defined over Cartesian product sets, and proximal point methods, among others. The auxiliary problem of the general algorithm also induces equivalent optimization reformulation and descent methods for asymmetric variational inequalities. We study the convergence properties of the general algorithm when applied to unconstrained optimization, nondifferentiable optimization, constrained differentiable optimization, and variational inequalities; the emphasis of the convergence analyses is placed on basic convergence results, convergence using different line search strategies and truncated subproblem solutions, and convergence rate results. This analysis offer a unification of known results; moreover, it provides strengthenings of convergence results for many existing algorithms, and indicates possible improvements of their realizations. 482 refs

  6. Search Patterns

    CERN Document Server

    Morville, Peter

    2010-01-01

    What people are saying about Search Patterns "Search Patterns is a delight to read -- very thoughtful and thought provoking. It's the most comprehensive survey of designing effective search experiences I've seen." --Irene Au, Director of User Experience, Google "I love this book! Thanks to Peter and Jeffery, I now know that search (yes, boring old yucky who cares search) is one of the coolest ways around of looking at the world." --Dan Roam, author, The Back of the Napkin (Portfolio Hardcover) "Search Patterns is a playful guide to the practical concerns of search interface design. It cont

  7. Personalized Search

    CERN Document Server

    AUTHOR|(SzGeCERN)749939

    2015-01-01

    As the volume of electronically available information grows, relevant items become harder to find. This work presents an approach to personalizing search results in scientific publication databases. This work focuses on re-ranking search results from existing search engines like Solr or ElasticSearch. This work also includes the development of Obelix, a new recommendation system used to re-rank search results. The project was proposed and performed at CERN, using the scientific publications available on the CERN Document Server (CDS). This work experiments with re-ranking using offline and online evaluation of users and documents in CDS. The experiments conclude that the personalized search result outperform both latest first and word similarity in terms of click position in the search result for global search in CDS.

  8. Mastering Search Analytics Measuring SEO, SEM and Site Search

    CERN Document Server

    Chaters, Brent

    2011-01-01

    Many companies still approach Search Engine Optimization (SEO) and paid search as separate initiatives. This in-depth guide shows you how to use these programs as part of a comprehensive strategy-not just to improve your site's search rankings, but to attract the right people and increase your conversion rate. Learn how to measure, test, analyze, and interpret all of your search data with a wide array of analytic tools. Gain the knowledge you need to determine the strategy's return on investment. Ideal for search specialists, webmasters, and search marketing managers, Mastering Search Analyt

  9. Text Mining Metal-Organic Framework Papers.

    Science.gov (United States)

    Park, Sanghoon; Kim, Baekjun; Choi, Sihoon; Boyd, Peter G; Smit, Berend; Kim, Jihan

    2018-02-26

    We have developed a simple text mining algorithm that allows us to identify surface area and pore volumes of metal-organic frameworks (MOFs) using manuscript html files as inputs. The algorithm searches for common units (e.g., m 2 /g, cm 3 /g) associated with these two quantities to facilitate the search. From the sample set data of over 200 MOFs, the algorithm managed to identify 90% and 88.8% of the correct surface area and pore volume values. Further application to a test set of randomly chosen MOF html files yielded 73.2% and 85.1% accuracies for the two respective quantities. Most of the errors stem from unorthodox sentence structures that made it difficult to identify the correct data as well as bolded notations of MOFs (e.g., 1a) that made it difficult identify its real name. These types of tools will become useful when it comes to discovering structure-property relationships among MOFs as well as collecting a large set of data for references.

  10. Internal bremsstrahlung signatures in light of direct dark matter searches

    International Nuclear Information System (INIS)

    Garny, Mathias; Ibarra, Alejandro; Pato, Miguel; Vogl, Stefan

    2013-07-01

    Although proposed long ago, the search for internal bremsstrahlung signatures has only recently been made possible by the excellent energy resolution of ground-based and satellite-borne gamma-ray instruments. Here, we investigate thoroughly the current status of internal bremsstrahlung searches in light of the results of direct dark matter searches and in the framework of minimal mass-degenerate scenarios. The constraints set by Fermi-LAT and H.E.S.S. extend uninterrupted from tens of GeV up to tens of TeV and are rather insensitive to the mass degeneracy in the particle physics model. In contrast, direct searches are best in the moderate to low mass splitting regime, where XENON100 limits overshadow Fermi-LAT and H.E.S.S. up to TeV masses if dark matter couples to (light) quarks. We examine carefully the prospects for GAMMA-400, CTA and XENON1T, all planned to come online in the near future, and find that: (a) CTA and XENON1T are fully complementary, with CTA most sensitive to multi-TeV masses and mass splittings around 10%, and XENON1T probing best small mass splittings up to TeV masses; and (b) current constraints from XENON100 already preclude the observation of any spectral feature with GAMMA-400 in spite of its impressive energy resolution, unless dark matter does not couple to light quarks. Finally, we point out that, unlike for direct searches, the possibility of detecting thermal relics in upcoming internal bremsstrahlung searches requires boost factors larger than ∝10.

  11. Internal bremsstrahlung signatures in light of direct dark matter searches

    Energy Technology Data Exchange (ETDEWEB)

    Garny, Mathias [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Ibarra, Alejandro; Pato, Miguel; Vogl, Stefan [Technische Univ. Muenchen, Garching (Germany). Physik Dept. T30d

    2013-06-15

    Although proposed long ago, the search for internal bremsstrahlung signatures has only recently been made possible by the excellent energy resolution of ground-based and satellite-borne gamma-ray instruments. Here, we investigate thoroughly the current status of internal bremsstrahlung searches in light of the results of direct dark matter searches and in the framework of minimal mass-degenerate scenarios. The constraints set by Fermi-LAT and H.E.S.S. extend uninterrupted from tens of GeV up to tens of TeV and are rather insensitive to the mass degeneracy in the particle physics model. In contrast, direct searches are best in the moderate to low mass splitting regime, where XENON100 limits overshadow Fermi-LAT and H.E.S.S. up to TeV masses if dark matter couples to (light) quarks. We examine carefully the prospects for GAMMA-400, CTA and XENON1T, all planned to come online in the near future, and find that: (a) CTA and XENON1T are fully complementary, with CTA most sensitive to multi-TeV masses and mass splittings around 10%, and XENON1T probing best small mass splittings up to TeV masses; and (b) current constraints from XENON100 already preclude the observation of any spectral feature with GAMMA-400 in spite of its impressive energy resolution, unless dark matter does not couple to light quarks. Finally, we point out that, unlike for direct searches, the possibility of detecting thermal relics in upcoming internal bremsstrahlung searches requires boost factors larger than {proportional_to}10.

  12. Prospects for charged Higgs searches at the LHC

    CERN Document Server

    Akeroyd, A.G.; Arhrib, A.; Basso, L.; Ginzburg, I.F.; Guedes, R.; Hernandez-Sanchez, J.; Huitu, K.; Hurth, T.; Kadastik, M.; Kanemura, S.; Kannike, K.; Khater, W.; Krawczyk, M.; Mahmoudi, F.; Moretti, S.; Najjari, S.; Osland, P.; Pruna, G.M.; Purmohammadi, M.; Racioppi, A.; Raidal, M.; Santos, R.; Sharma, P.; Sokolowska, D.; Staal, O.; Yagyu, K.; Yildirim, E.

    2017-05-03

    The goal of this report is to summarize the current situation and discuss possible search strategies for charged scalars, in non-supersymmetric extensions of the Standard Model at the LHC. Such scalars appear in Multi-Higgs-Doublet models (MHDM), in particular in the popular Two-Higgs-Doublet model (2HDM), allowing for charged and more neutral Higgs bosons. These models have the attractive property that electroweak precision observables are automatically in agreement with the Standard Model at the tree level. For the most popular version of this framework, Model~II, a discovery of a charged Higgs boson remains challenging, since the parameter space is becoming very constrained, and the QCD background is very high. We also briefly comment on models with dark matter which constrain the corresponding charged scalars that occur in these models. The stakes of a possible discovery of an extended scalar sector are very high, and these searches should be pursued in all conceivable channels, at the LHC and at future c...

  13. Prospects for charged Higgs searches at the LHC

    International Nuclear Information System (INIS)

    Akeroyd, A.G.; Moretti, S.; Yagyu, K.; Yildirim, E.; Aoki, M.; Arhrib, A.; Basso, L.; Ginzburg, I.F.; Guedes, R.; Hernandez-Sanchez, J.; Huitu, K.; Hurth, T.; Kadastik, M.; Kannike, K.; Racioppi, A.; Raidal, M.; Kanemura, S.; Khater, W.; Krawczyk, M.; Najjari, S.; Sokolowska, D.; Mahmoudi, F.; Osland, P.; Purmohammadi, M.; Pruna, G.M.; Santos, R.; Sharma, P.; Staal, O.

    2017-01-01

    The goal of this report is to summarize the current situation and discuss possible search strategies for charged scalars, in non-supersymmetric extensions of the Standard Model at the LHC. Such scalars appear in Multi-Higgs-Doublet models, in particular in the popular Two-Higgs-Doublet model, allowing for charged and additional neutral Higgs bosons. These models have the attractive property that electroweak precision observables are automatically in agreement with the Standard Model at the tree level. For the most popular version of this framework, Model II, a discovery of a charged Higgs boson remains challenging, since the parameter space is becoming very constrained, and the QCD background is very high. We also briefly comment on models with dark matter which constrain the corresponding charged scalars that occur in these models. The stakes of a possible discovery of an extended scalar sector are very high, and these searches should be pursued in all conceivable channels, at the LHC and at future colliders. (orig.)

  14. Prospects for charged Higgs searches at the LHC

    Energy Technology Data Exchange (ETDEWEB)

    Akeroyd, A.G.; Moretti, S.; Yagyu, K.; Yildirim, E. [University of Southampton, School of Physics and Astronomy, Southampton (United Kingdom); Aoki, M. [Kanazawa University, Institute for Theoretical Physics, Kanazawa (Japan); Arhrib, A. [Universite Abdelmalek Essaadi, Departement de Mathematique, Faculte des Sciences et Techniques, Tangier (Morocco); Faculte des Sciences-Semlalia, LPHEA, Marrakesh (Morocco); Basso, L. [CPPM, Aix-Marseille Universite, CNRS-IN2P3, UMR 7346, Marseille Cedex 9 (France); Ginzburg, I.F. [Novosibirsk University, Sobolev Institute of Mathematics SB RAS, Novosibirsk (Russian Federation); Guedes, R. [FCSH - New University of Lisbon, IHC, Instituto de Historia Contemporanea, Lisbon (Portugal); Hernandez-Sanchez, J. [Benemerita Universidad Autonoma de Puebla, Facultad de Ciencias de la Electronica, Puebla, Puebla (Mexico); Dual C-P Institute of High Energy Physics, Colima (Mexico); Huitu, K. [University of Helsinki, Department of Physics, and Helsinki Institute of Physics, Helsinki (Finland); Hurth, T. [Johannes Gutenberg University, PRISMA Cluster of Excellence and Institute for Physics (THEP), Mainz (Germany); Kadastik, M.; Kannike, K.; Racioppi, A.; Raidal, M. [National Institute of Chemical Physics and Biophysics, Tallinn (Estonia); Kanemura, S. [University of Toyama, Department of Physics, Toyama (Japan); Khater, W. [Birzeit University, Department of Physics, West Bank (Palestinian Territory, Occupied); Krawczyk, M.; Najjari, S.; Sokolowska, D. [University of Warsaw, Faculty of Physics, Warsaw (Poland); Mahmoudi, F. [Lyon 1 Univ., ENS de Lyon, CNRS, Centre de Recherche Astrophysique de Lyon, UMR5574, Saint-Genis-Laval (France); CERN, Theoretical Physics Department, Geneva 23 (Switzerland); Osland, P.; Purmohammadi, M. [University of Bergen, Department of Physics and Technology, Postboks 7803, Bergen (Norway); Pruna, G.M. [Paul Scherrer Institute, Villigen (Switzerland); Santos, R. [Universidade de Lisboa, Campo Grande, Centro de Fisica Teorica e Computacional, Faculdade de Ciencias, Lisbon (Portugal); Instituto Superior de Engenharia de Lisboa - ISEL, Lisbon (Portugal); Sharma, P. [The University of Adelaide, Center of Excellence in Particle Physics (CoEPP), Adelaide, SA (Australia); Staal, O. [Stockholm University, Department of Physics, The Oskar Klein Centre, Stockholm (Sweden)

    2017-05-15

    The goal of this report is to summarize the current situation and discuss possible search strategies for charged scalars, in non-supersymmetric extensions of the Standard Model at the LHC. Such scalars appear in Multi-Higgs-Doublet models, in particular in the popular Two-Higgs-Doublet model, allowing for charged and additional neutral Higgs bosons. These models have the attractive property that electroweak precision observables are automatically in agreement with the Standard Model at the tree level. For the most popular version of this framework, Model II, a discovery of a charged Higgs boson remains challenging, since the parameter space is becoming very constrained, and the QCD background is very high. We also briefly comment on models with dark matter which constrain the corresponding charged scalars that occur in these models. The stakes of a possible discovery of an extended scalar sector are very high, and these searches should be pursued in all conceivable channels, at the LHC and at future colliders. (orig.)

  15. Assessment of Evaluation Frameworks for Design of a Sexual Risk Prevention Game for Black Adolescent Girls.

    Science.gov (United States)

    Sockolow, Paulina; Joppa, Meredith; Zhu, Jichen

    2018-01-01

    Adolescent sexual risk behavior (SRB), a major public health problem affects urban Black adolescent girls increasing their health disparities and risks for sexually transmitted infections. Collaborating with these adolescents, we designed a game for smartphones that incorporates elements of trauma-informed care and social cognitive theory to reduce SRB. Game researchers promote use of a comprehensive, multipurpose framework for development and evaluation of games for health applications. Our first game development step was framework selection and measurable health outcomes identification. Literature search identified two health game frameworks, both incorporating pedagogical theory, learning theory, and gaming requirements. Arnab used the IM + LM-GM framework to develop and implement a game in a school intervention program. Yusoff's framework was developed for use during game design. We investigated concordance and discordance between our SRB game design characteristics and each framework's components. Findings indicated Arnab's framework was sufficiently comprehensive to guide development of our game and outcome measure selection.

  16. Search Help

    Science.gov (United States)

    Guidance and search help resource listing examples of common queries that can be used in the Google Search Appliance search request, including examples of special characters, or query term seperators that Google Search Appliance recognizes.

  17. Search and foraging behaviors from movement data: A comparison of methods.

    Science.gov (United States)

    Bennison, Ashley; Bearhop, Stuart; Bodey, Thomas W; Votier, Stephen C; Grecian, W James; Wakefield, Ewan D; Hamer, Keith C; Jessopp, Mark

    2018-01-01

    Search behavior is often used as a proxy for foraging effort within studies of animal movement, despite it being only one part of the foraging process, which also includes prey capture. While methods for validating prey capture exist, many studies rely solely on behavioral annotation of animal movement data to identify search and infer prey capture attempts. However, the degree to which search correlates with prey capture is largely untested. This study applied seven behavioral annotation methods to identify search behavior from GPS tracks of northern gannets ( Morus bassanus ), and compared outputs to the occurrence of dives recorded by simultaneously deployed time-depth recorders. We tested how behavioral annotation methods vary in their ability to identify search behavior leading to dive events. There was considerable variation in the number of dives occurring within search areas across methods. Hidden Markov models proved to be the most successful, with 81% of all dives occurring within areas identified as search. k -Means clustering and first passage time had the highest rates of dives occurring outside identified search behavior. First passage time and hidden Markov models had the lowest rates of false positives, identifying fewer search areas with no dives. All behavioral annotation methods had advantages and drawbacks in terms of the complexity of analysis and ability to reflect prey capture events while minimizing the number of false positives and false negatives. We used these results, with consideration of analytical difficulty, to provide advice on the most appropriate methods for use where prey capture behavior is not available. This study highlights a need to critically assess and carefully choose a behavioral annotation method suitable for the research question being addressed, or resulting species management frameworks established.

  18. Commentary on a framework for multicultural education.

    Science.gov (United States)

    Hammerich, Karin F

    2014-09-01

    Today's changing demographics require that multicultural factors be considered in the delivery of quality patient-centred health care in chiropractic. Yet minimal training in cultural competency in chiropractic education leaves graduates ill-equipped to treat a diverse population. This commentary examines cultural competency training in current literature, demonstrates frameworks for curriculum integration, and suggests how cultural competency might be included in a chiropractic college curriculum. A database search yielded little evidence that cultural competency is integrated into curricula of chiropractic schools. Some journal articles note that promoting multicultural education and cultural sensitivity is an important goal. However, they provide no mechanisms as to how this can be achieved within training programs. Thus, although an undeniable need exists for all healthcare practitioners to develop cultural competency in the face of an increasingly diverse population, cultural competency education has not kept pace. Chiropractic schools must review their curricula to develop the cultural competencies of their graduates and a basic framework is suggested.

  19. The exploration-exploitation dilemma: a multidisciplinary framework.

    Directory of Open Access Journals (Sweden)

    Oded Berger-Tal

    Full Text Available The trade-off between the need to obtain new knowledge and the need to use that knowledge to improve performance is one of the most basic trade-offs in nature, and optimal performance usually requires some balance between exploratory and exploitative behaviors. Researchers in many disciplines have been searching for the optimal solution to this dilemma. Here we present a novel model in which the exploration strategy itself is dynamic and varies with time in order to optimize a definite goal, such as the acquisition of energy, money, or prestige. Our model produced four very distinct phases: Knowledge establishment, Knowledge accumulation, Knowledge maintenance, and Knowledge exploitation, giving rise to a multidisciplinary framework that applies equally to humans, animals, and organizations. The framework can be used to explain a multitude of phenomena in various disciplines, such as the movement of animals in novel landscapes, the most efficient resource allocation for a start-up company, or the effects of old age on knowledge acquisition in humans.

  20. Virtual shelves in a digital library: a framework for access to networked information sources.

    Science.gov (United States)

    Patrick, T B; Springer, G K; Mitchell, J A; Sievert, M E

    1995-01-01

    Develop a framework for collections-based access to networked information sources that addresses the problem of location-dependent access to information sources. This framework uses a metaphor of a virtual shelf. A virtual shelf is a general-purpose server that is dedicated to a particular information subject class. The identifier of one of these servers identifies its subject class. Location-independent call numbers are assigned to information sources. Call numbers are based on standard vocabulary codes. The call numbers are first mapped to the location-independent identifiers of virtual shelves. When access to an information resource is required, a location directory provides a second mapping of these location-independent server identifiers to actual network locations. The framework has been implemented in two different systems. One system is based on the Open System Foundation/Distributed Computing Environment and the other is based on the World Wide Web. This framework applies in new ways traditional methods of library classification and cataloging. It is compatible with two traditional styles of selecting information searching and browsing. Traditional methods may be combined with new paradigms of information searching that will be able to take advantage of the special properties of digital information. Cooperation between the library-informational science community and the informatics community can provide a means for a continuing application of the knowledge and techniques of library science to the new problems of networked information sources.