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Sample records for baseline characteristics glycaemia

  1. Evolution of glycaemia during irradiation syndrome

    International Nuclear Information System (INIS)

    The evolution of glycaemia following irradiation has been followed in the rat and pig. The results concerning a case of human accidental exposure have also been included. The author has tried to see whether the observed variations are reproducible and have a prognostic value. (author)

  2. Experimental Evaluation of Aerodynamics Characteristics of a Baseline Airfoil

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    Md. Rasedul Islam

    2015-01-01

    Full Text Available A wind tunnel test of baseline airfoil NACA 0015 model was conducted in the Wind tunnel wall test section of the Department of Mechanical Engineering at KUET, Bangladesh . The primary goal of the test was to measure airfoil aerodynamic characteristics over a wide range of Angle of Attack (AOA mainly from Zero degree to 20 degree AOA and with a wind tunnel fixed free stream velocity of 12m/s and at Re = 1.89×105 . The pressure distribution in both upper and lower camber surface was calculated with the help of digital pressure manometer. After analysis the value of Cl and Cd was found around 1.3 and 0.31 respectively.

  3. Impact of postprandial glycaemia on health and prevention of disease

    DEFF Research Database (Denmark)

    Blaak, E E; Antoine, J-M; Benton, D;

    2012-01-01

    Postprandial glucose, together with related hyperinsulinemia and lipidaemia, has been implicated in the development of chronic metabolic diseases like obesity, type 2 diabetes mellitus (T2DM) and cardiovascular disease (CVD). In this review, available evidence is discussed on postprandial glucose......, or the duration of the measurement of postprandial glycaemia is limited. It is evident that more randomized controlled dietary intervention trials using effective low vs. high glucose response diets are necessary in order to draw more definite conclusions on the role of postprandial glycaemia in relation...... to health and disease. Also of importance is the evaluation of the potential role of the time course of postprandial glycaemia....

  4. The LIFE Cognition Study: design and baseline characteristics

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    Sink KM

    2014-08-01

    adults at increased risk for incident mobility disability. One LIFE Study objective is to evaluate the effects of a structured physical activity program on changes in cognitive function and incident all-cause mild cognitive impairment or dementia. Here, we present the design and baseline cognitive data. At baseline, participants completed the modified Mini Mental Status Examination, Hopkins Verbal Learning Test, Digit Symbol Coding, Modified Rey–Osterrieth Complex Figure, and a computerized battery, selected to be sensitive to changes in speed of processing and executive functioning. During follow up, participants completed the same battery, along with the Category Fluency for Animals, Boston Naming, and Trail Making tests. The description of the mild cognitive impairment/dementia adjudication process is presented here. Participants with worse baseline Short Physical Performance Battery scores (prespecified at ≤7 had significantly lower median cognitive test scores compared with those having scores of 8 or 9 with modified Mini Mental Status Examination score of 91 versus (vs 93, Hopkins Verbal Learning Test delayed recall score of 7.4 vs 7.9, and Digit Symbol Coding score of 45 vs 48, respectively (all P<0.001. The LIFE Study will contribute important information on the effects of a structured physical activity program on cognitive outcomes in sedentary older adults at particular risk for mobility impairment. In addition to its importance in the area of prevention of cognitive decline, the LIFE Study will also likely serve as a model for exercise and other behavioral intervention trials in older adults. Keywords: exercise, physical activity, older adults, dementia

  5. Baseline Characteristics in the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT)

    NARCIS (Netherlands)

    Pfeffer, Marc A.; Burdmann, Emmanuel A.; Chen, Chao-Yin; Cooper, Mark E.; de Zeeuw, Dick; Eckardt, Kai-Uwe; Ivanovich, Peter; Kewalramani, Reshma; Levey, Andrew S.; Lewis, Eldrin F.; McGill, Janet; McMurray, John J. V.; Parfrey, Patrick; Parving, Hans-Henrik; Remuzzi, Giuseppe; Singh, Ajay K.; Solomon, Scott D.; Toto, Robert; Uno, Hajime

    2009-01-01

    Background: Anemia augments the already high rates of fatal and major nonfatal cardiovascular and renal events in individuals with type 2 diabetes. In 2004, we initiated the Trial to Reduce Cardiovascular Events With Aranesp Therapy (TREAT). This report presents the baseline characteristics and ther

  6. Impact of baseline characteristics on outcomes of carotid artery stenting in acute ischemic stroke patients

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    Yu CS

    2016-03-01

    Full Text Available Cheng-Sheng Yu,1,* Chih-Ming Lin,2,3,* Chi-Kuang Liu,4 Henry Horng-Shing Lu1 1Institute of Statistics and Big Data Research Center, National Chiao Tung University, Hsinchu, 2Stroke Centre and Department of Neurology, Chunghua Christian Hospital, Chunghua, 3Graduate Institute of Biological Science and Technology, National Chiao Tung University, Hsinchu, 4Department of Medical Imaging, Chunghua Christian Hospital, Chunghua, Taiwan, Republic of China *These authors contributed equally to this work Abstract: Carotid artery stenting is an effective treatment for ischemic stroke patients with moderate-to-severe carotid artery stenosis. However, the midterm outcome for patients undergoing this procedure varies considerably with baseline characteristics. To determine the impact of baseline characteristics on outcomes following carotid artery stenting, data from 107 eligible patients with a first episode of ischemic stroke were collected by retrospective chart review. A modified Rankin Scale (mRS was used to divide patients into two baseline groups, mRS ≤2 and mRS >2. A three-step decision-tree statistical analysis was conducted. After weighting the decision-tree parameters, the following impact hierarchy was obtained: admission low-density lipoprotein, gouty arthritis, chronic kidney disease, ipsilateral common carotid artery resistance index, contralateral ophthalmic artery resistance index, sex, and dyslipidemia. The finite-state machine model demonstrated that, in patients with baseline mRS ≤2, 46% had an improved mRS score at follow-up, whereas 54% had a stable mRS score. In patients with baseline mRS >2, a stable mRS score was observed in 75%, improved score in 23%, and a poorer score in 2%. Admission low-density lipoprotein was the strongest predictive factor influencing poststenting outcome. In addition, our study provides further evidence that carotid artery stenting can be of benefit in first-time ischemic stroke patients with baseline m

  7. Cumulative glycaemia as measured by lens fluorometry: association with retinopathy in type 2 diabetes

    DEFF Research Database (Denmark)

    Munch, I C; Larsen, M; Borch-Johnsen, Knut; Glümer, C; Lund-Andersen, H; Kessel, L

    2011-01-01

    The aim of this study was to assess the association between lifelong cumulative glycaemia estimated by lens fluorometry and the presence of retinopathy in individuals with type 2 diabetes.......The aim of this study was to assess the association between lifelong cumulative glycaemia estimated by lens fluorometry and the presence of retinopathy in individuals with type 2 diabetes....

  8. Physical Fitness of Police Academy Cadets: Baseline Characteristics and Changes During a 16-Week Academy

    Science.gov (United States)

    Sherman, Ross A.; Crawley, William R.; Cosio-Lima, Ludmila M.

    2016-01-01

    Abstract Crawley, AA, Sherman, RA, Crawley, WR, and Cosio-Lima, LM. Physical fitness of police academy cadets: baseline characteristics and changes during a 16-week academy. J Strength Cond Res 30(5): 1416–1424, 2016—Police academies traditionally emphasize the importance of being physically fit. The purpose of this research was to determine cadet baseline physical fitness characteristics and assess effectiveness of a 16-week training program. Sixty-eight cadets (61 men, 7 women) volunteered to have baseline physical fitness characteristics assessed, and 55 cadets (49 men, 6 women) completed further testing at weeks 8 and 16. The testing comprised hand grip (strength), arm crank (upper-body power), 30 seconds Wingate (lower body power), sum of skinfolds and percentage body fat (body composition), 40-yard dash (sprint speed), 1 repetition maximum bench press (strength), T-test (agility), and sit-and-reach (flexibility). In addition, cadets completed standardized state testing (push-ups, sit-ups, vertical jump, and half-mile shuttle run). The training program consisted of 1 hour sessions, 3 d·wk−1, including aerobic, plyometrics, body weight, and resistance exercise. Significant changes were found in agility (p < 0.01), upper-body and lower-body peak power (p ≤ 0.05), sit-ups (p < 0.01), push-ups (p ≤ 0.05) across the first 8 weeks, and in agility (p ≤ 0.05), lower-body peak power (p ≤ 0.05), sit-ups (p < 0.01), push-ups (p ≤ 0.05), half-mile shuttle run (p < 0.01) across the full 16 weeks. However, none of the variables showed significant change across the second half of the program (weeks 8–16). A number of individual parameters of physical fitness showed evidence of improvement in the first 8 weeks, whereas none of the variables showed significant improvement in the second 8 weeks. This suggests modifications could be made to increase overall effectiveness of cadet physical training specifically after the 8-week mark. PMID:26466133

  9. Physical Fitness of Police Academy Cadets: Baseline Characteristics and Changes During a 16-Week Academy.

    Science.gov (United States)

    Crawley, Amy A; Sherman, Ross A; Crawley, William R; Cosio-Lima, Ludmila M

    2016-05-01

    Crawley, AA, Sherman, RA, Crawley, WR, and Cosio-Lima, LM. Physical fitness of police academy cadets: baseline characteristics and changes during a 16-week academy. J Strength Cond Res 30(5): 1416-1424, 2016-Police academies traditionally emphasize the importance of being physically fit. The purpose of this research was to determine cadet baseline physical fitness characteristics and assess effectiveness of a 16-week training program. Sixty-eight cadets (61 men, 7 women) volunteered to have baseline physical fitness characteristics assessed, and 55 cadets (49 men, 6 women) completed further testing at weeks 8 and 16. The testing comprised hand grip (strength), arm crank (upper-body power), 30 seconds Wingate (lower body power), sum of skinfolds and percentage body fat (body composition), 40-yard dash (sprint speed), 1 repetition maximum bench press (strength), T-test (agility), and sit-and-reach (flexibility). In addition, cadets completed standardized state testing (push-ups, sit-ups, vertical jump, and half-mile shuttle run). The training program consisted of 1 hour sessions, 3 d·wk, including aerobic, plyometrics, body weight, and resistance exercise. Significant changes were found in agility (p < 0.01), upper-body and lower-body peak power (p ≤ 0.05), sit-ups (p < 0.01), push-ups (p ≤ 0.05) across the first 8 weeks, and in agility (p ≤ 0.05), lower-body peak power (p ≤ 0.05), sit-ups (p < 0.01), push-ups (p ≤ 0.05), half-mile shuttle run (p < 0.01) across the full 16 weeks. However, none of the variables showed significant change across the second half of the program (weeks 8-16). A number of individual parameters of physical fitness showed evidence of improvement in the first 8 weeks, whereas none of the variables showed significant improvement in the second 8 weeks. This suggests modifications could be made to increase overall effectiveness of cadet physical training specifically after the 8-week mark. PMID:26466133

  10. Environmental Baseline Characteristics for a Pilot Project Site for Integrated Solid Waste Management in Makurdi, Nigeria

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    S.V. Irtwange

    2009-10-01

    Full Text Available The study of the pilot project site for integrated solid waste management in Makurdi, Nigeria wasconducted to establish the environmental baseline characteristics as part of an Environmental ImpactAssessment (EIA process. Survey of literature was conducted to generate information on climate, geology, andthe general physical, chemical and biological status of the environment as well as identify information gaps.This was achieved through the consultation of existing studies/survey reports, technical publications, textbooks,etc. Field data gathering exercise was conducted to fill information gap identified from desk survey and alsoto validate existing information. It entailed visual observation, interviews, on-site measurements and collectionof samples for laboratory analysis and testing. The study covered terrain/topography, climate and meteorology,land ownership, land use and zoning, soil quality, geological formations underneath the project site, hydrologyand water quality, groundwater geophysical survey, hydro geology, ambient air quality, ecology of the projectsite and surroundings, baseline noise levels and public consultation. The results of the study indicates that theenvironmental components of the site were within natural background levels of the environment except theoutcrops of the Makurdi sandstone in the designated land fill areas having served as a road constructionexcavation site in the past. The study also shows that apart from the nearby stream, there are no existingenvironmental stresses or pollution within the area.

  11. Baseline characteristics influencing quality of life in women undergoing gynecologic oncology surgery

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    Jenison Eric L

    2007-05-01

    -being. Models that included PCS and MCS accounted for 30 to 44% of the variability in baseline physical, emotional, and functional well-being on the FACT-G. Conclusion At the time of diagnosis and treatment, patients' QoL is affected by inherent characteristics. Assessment of treatment outcome should take into account the effect of these independent variables. As treatment options become more complex, these variables are likely to be of increasing importance in evaluating treatment effects on QoL.

  12. Baseline characteristics of patients in the reduction of events with darbepoetin alfa in heart failure trial (RED-HF)

    OpenAIRE

    McMurray, J J V; Anand, I. S.; Diaz, R.; Maggioni, A. P.; O'Connor, C; Pfeffer, M. A.; Solomon, S D; M. Tendera; van Veldhuisen, D J; Albizem, M.; Cheng, S.; Scarlata, D.; Young, J B; Amuchastegui, M.; Belziti, C.

    2013-01-01

    Aims: This report describes the baseline characteristics of patients in the Reduction of Events with Darbepoetin alfa in Heart Failure trial (RED-HF) which is testing the hypothesis that anaemia correction with darbepoetin alfa will reduce the composite endpoint of death from any cause or hospital admission for worsening heart failure, and improve other outcomes. Methods and results: Key demographic, clinical, and laboratory findings, along with baseline treatment, are reported and compar...

  13. Baseline Characteristics and Risk Factors of Pulmonary Arterial Hypertension in Systemic Lupus Erythematosus Patients.

    Science.gov (United States)

    Huang, Can; Li, Mengtao; Liu, Yongtai; Wang, Qian; Guo, Xiaoxiao; Zhao, Jiuliang; Lai, Jinzhi; Tian, Zhuang; Zhao, Yan; Zeng, Xiaofeng

    2016-03-01

    Peking Union Medical College Hospital (PUMCH) has started a single-center right heart catheterization (RHC)-based pulmonary arterial hypertension (PAH) study in systemic lupus erythematosus (SLE) since 2006. The baseline characteristics of these patients were described and the risk factor for PAH in lupus was identified.The demographic, clinical, laboratory, and treatment characteristics of SLE patients with PAH when they were registered were collected as the baseline data. A case-control study was conducted by taking the admitted SLE-non-PAH patients adjusted for age and gender in a 4:1 ratio during the same period as the controls. The associated variables were examined by binary multivariate logistic regression analysis to identify possible risk factors. A total of 111 RHC-confirmed SLE-PAH patients were enrolled, with the onset age of 34.6 ± 8.6 years old and the average SLE duration of 5 years. RHC revealed mPAP as 46.4 ± 11.4 mm Hg, CI as 2.7 ± 0.8 L/min × m, and PVR as 10.5 ± 4.8 WU. 46% of patients were WHO Fc I-II. All patients were treated with immunosuppressive agents and 65% patients had PAH-targeted therapy. The case-control study had confirmed 2 independent risk factors previously published: pericardial effusion (OR = 21.290, P RNP antibody (OR = 12.399, P antibody (OR = 4.836, P = 0.004), SLEDAI≤9 (OR = 26.426, P  357 μmol/L (OR = 9.666, P RNP antibody are risk factors for SLE-associated PAH. Long SLE disease duration, the presence of interstitial lung disease, without acute skin rash, positive anti-SSA antibody, low SLEDAI and ESR, and high uric acid levels are also associated with PAH in SLE patients. PMID:26962774

  14. Dynamic volume perfusion CT in patients with lung cancer: Baseline perfusion characteristics of different histological subtypes

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    Shi, Jingyun, E-mail: shijingyun89179@126.com [Department of Radiology, Shanghai Pulmonary Hospital, Tongji University School of Medicine (China); Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim (Germany); Schmid-Bindert, Gerald, E-mail: gerald.schmid-bindert@medma.uni-heidelberg.de [Division of Surgical Oncology and Thoracic Surgery, Department of Surgery, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim (Germany); Fink, Christian, E-mail: Christian.Fink@akh-celle.de [Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim (Germany); Sudarski, Sonja, E-mail: sonja_sudarski@gmx.de [Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim (Germany); Apfaltrer, Paul, E-mail: Paul.Apfaltrer@medma.uni-heidelberg.de [Institute of Clinical Radiology and Nuclear Medicine, University Medical Center Mannheim, Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1-3, 68167 Mannheim (Germany); Pilz, Lothar R., E-mail: Lothar.Pilz@medma.uni-heidelberg.de [Medical Faculty Mannheim, Heidelberg University, Theodor-Kutzer-Ufer 1, 68167 Mannheim (Germany); Liu, Bo, E-mail: bo.liu@siemens.com [Siemens Healthcare, No. 278, Zhouzhu Road, Shanghai, 201318 (China); Haberland, Ulrike, E-mail: ulrike.haberland@siemens.com [Siemens Healthcare Sector, H IM CR R and D PA SC, Siemensstraße 1, 91301 Forchheim (Germany); Klotz, Ernst, E-mail: ernst.klotz@siemens.com [Siemens Healthcare Sector, H IM CR R and D PA SC, Siemensstraße 1, 91301 Forchheim (Germany); and others

    2013-12-01

    Objective: To evaluate dynamic volume perfusion CT (dVPCT) tumor baseline characteristics of three different subtypes of lung cancer in untreated patients. Materials and methods: 173 consecutive patients (131 men, 42 women; mean age 61 ± 10 years) with newly diagnosed lung cancer underwent dVPCT prior to biopsy. Tumor permeability, blood flow (BF), blood volume (BV) and mean transit time (MTT) were quantitatively assessed as well as tumor diameter and volume. Tumor subtypes were histologically determined and compared concerning their dVPCT results. dVPCT results were correlated to tumor diameter and volume. Results: Histology revealed adenocarcinoma in 88, squamous cell carcinoma in 54 and small cell lung cancer (SCLC) in 31 patients. Tumor permeability was significantly differing between adenocarcinoma, squamous cell carcinoma and SCLC (all p < 0.05). Tumor BF and BV were higher in adenocarcinomathan in SCLC (p = 0.001 and p = 0.0002 respectively). BV was also higher in squamous cell carcinoma compared to SCLC (p = 0.01). MTT was not differing between tumor subtypes. Regarding all tumors, tumor diameter did not correlate with any of the dVPCT parameters, whereas tumor volume was negatively associated with permeability, BF and BV (r = −0.22, −0.24, −0.24, all p < 0.05). In squamous cell carcinoma, tumor diameter und volume correlated with BV (r = 0.53 and r = −0.40, all p < 0.05). In SCLC, tumor diameter und volume correlated with MTT (r = 0.46 and r = 0.39, all p < 0.05). In adenocarcinoma, no association between morphological and functional tumor characteristics was observed. Conclusions: dVPCT parameters are only partially related to tumor diameter and volume and are significantly differing between lung cancer subtypes.

  15. Dynamic volume perfusion CT in patients with lung cancer: Baseline perfusion characteristics of different histological subtypes

    International Nuclear Information System (INIS)

    Objective: To evaluate dynamic volume perfusion CT (dVPCT) tumor baseline characteristics of three different subtypes of lung cancer in untreated patients. Materials and methods: 173 consecutive patients (131 men, 42 women; mean age 61 ± 10 years) with newly diagnosed lung cancer underwent dVPCT prior to biopsy. Tumor permeability, blood flow (BF), blood volume (BV) and mean transit time (MTT) were quantitatively assessed as well as tumor diameter and volume. Tumor subtypes were histologically determined and compared concerning their dVPCT results. dVPCT results were correlated to tumor diameter and volume. Results: Histology revealed adenocarcinoma in 88, squamous cell carcinoma in 54 and small cell lung cancer (SCLC) in 31 patients. Tumor permeability was significantly differing between adenocarcinoma, squamous cell carcinoma and SCLC (all p < 0.05). Tumor BF and BV were higher in adenocarcinomathan in SCLC (p = 0.001 and p = 0.0002 respectively). BV was also higher in squamous cell carcinoma compared to SCLC (p = 0.01). MTT was not differing between tumor subtypes. Regarding all tumors, tumor diameter did not correlate with any of the dVPCT parameters, whereas tumor volume was negatively associated with permeability, BF and BV (r = −0.22, −0.24, −0.24, all p < 0.05). In squamous cell carcinoma, tumor diameter und volume correlated with BV (r = 0.53 and r = −0.40, all p < 0.05). In SCLC, tumor diameter und volume correlated with MTT (r = 0.46 and r = 0.39, all p < 0.05). In adenocarcinoma, no association between morphological and functional tumor characteristics was observed. Conclusions: dVPCT parameters are only partially related to tumor diameter and volume and are significantly differing between lung cancer subtypes

  16. Baseline characteristics of depressive disorders in Thai outpatients: findings from the Thai Study of Affective Disorders

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    Wongpakaran T

    2014-01-01

    Full Text Available Tinakon Wongpakaran,1 Nahathai Wongpakaran,1 Manee Pinyopornpanish,1 Usaree Srisutasanavong,1 Peeraphon Lueboonthavatchai,2 Raviwan Nivataphand,2 Nattaporn Apisiridej,3 Donruedee Petchsuwan,3 Nattha Saisavoey,4 Kamonporn Wannarit,4 Ruk Ruktrakul,5 Thawanrat Srichan,5 Sirina Satthapisit,6 Daochompu Nakawiro,7 Thanita Hiranyatheb,7 Anakevich Temboonkiat,8 Namtip Tubtimtong,9 Sukanya Rakkhajeekul,9 Boonsanong Wongtanoi,10 Sitthinant Tanchakvaranont,11 Putipong Bookkamana121Faculty of Medicine, Chiang Mai University, Chiang Mai, 2Faculty of Medicine, Chulalongkorn University, Bangkok, 3Trang Hospital, Trang, 4Faculty of Medicine, Siriraj Hospital, Mahidol University, Bangkok, 5Lampang Hospital, Lampang, 6KhonKaen Hospital, Khon Kaen, 7Faculty of Medicine, Ramathibodi Hospital, Mahidol University, Bangkok, 8Phramongkutklao Hospital, Bangkok, 9Faculty of Medicine Naresuan University, Pitsanulok, 10Srisangwal Hospital, Mae Hong Son, 11Queen Savang Vadhana Memorial Hospital, Chonburi, 12Faculty of Science, Chiang Mai University, Chiang Mai Kingdom of ThailandBackground: The Thai Study of Affective Disorders was a tertiary hospital-based cohort study developed to identify treatment outcomes among depressed patients and the variables involved. In this study, we examined the baseline characteristics of these depressed patients.Methods: Patients were investigated at eleven psychiatric outpatient clinics at tertiary hospitals for the presence of unipolar depressive disorders, as diagnosed by the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition. The severity of any depression found was measured using the Clinical Global Impression and 17-item Hamilton Depression Rating Scale (HAMD clinician-rated tools, with the Thai Depression Inventory (a self-rated instrument administered alongside them. Sociodemographic and psychosocial variables were collected, and quality of life was also captured using the health-related quality of life (SF-36v2

  17. The counseling african americans to control hypertension (caatch trial: baseline demographic, clinical, psychosocial, and behavioral characteristics

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    Diaz-Gloster Marleny

    2011-09-01

    Full Text Available Abstract Background Effectiveness of combined physician and patient-level interventions for blood pressure (BP control in low-income, hypertensive African Americans with multiple co-morbid conditions remains largely untested in community-based primary care practices. Demographic, clinical, psychosocial, and behavioral characteristics of participants in the Counseling African American to Control Hypertension (CAATCH Trial are described. CAATCH evaluates the effectiveness of a multi-level, multi-component, evidence-based intervention compared with usual care (UC in improving BP control among poorly controlled hypertensive African Americans who receive primary care in Community Health Centers (CHCs. Methods Participants included 1,039 hypertensive African Americans receiving care in 30 CHCs in the New York Metropolitan area. Baseline data on participant demographic, clinical (e.g., BP, anti-hypertensive medications, psychosocial (e.g., depression, medication adherence, self-efficacy, and behavioral (e.g., exercise, diet characteristics were gathered through direct observation, chart review, and interview. Results The sample was primarily female (71.6%, middle-aged (mean age = 56.9 ± 12.1 years, high school educated (62.4%, low-income (72.4% reporting less than $20,000/year income, and received Medicaid (35.9% or Medicare (12.6%. Mean systolic and diastolic BP were 150.7 ± 16.7 mm Hg and 91.0 ± 10.6 mm Hg, respectively. Participants were prescribed an average of 2.5 ± 1.9 antihypertensive medications; 54.8% were on a diuretic; 33.8% were on a beta blocker; 41.9% were on calcium channel blockers; 64.8% were on angiotensin converting enzyme (ACE inhibitors/angiotensin receptor blockers (ARBs. One-quarter (25.6% of the sample had resistant hypertension; one-half (55.7% reported medication non-adherence. Most (79.7% reported one or more co-morbid medical conditions. The majority of the patients had a Charlson Co-morbidity score ≥ 2. Diabetes

  18. BeLieving in Native Girls: Characteristics from a Baseline Assessment

    Science.gov (United States)

    Scott, Deborah; Langhorne, Aleisha

    2012-01-01

    BeLieving In Native Girls (BLING) is a juvenile delinquency and HIV intervention at a residential boarding school for American Indian/Alaska Native adolescent girls ages 12-20 years. In 2010, 115 participants completed baseline surveys to identify risk and protective factors. Initial findings are discussed regarding a variety of topics, including…

  19. Cohort profile: Lifelines DEEP, a prospective, general population cohort study in the northern Netherlands: study design and baseline characteristics

    OpenAIRE

    Tigchelaar, E.F.; Zhernakova, A; Dekens, J.A.M.; Hermes, G.D.A.; Baranska, A.; Mujagic, Z.; M.A. Swertz; Munoz, A.M.; Deelen, P.; Cenit, M. C.; Franke, L; Scholtens, S.; Stolk, R.P.; Wijmenga, C; Feskens, E.J.M.

    2015-01-01

    Purpose: There is a critical need for population-based prospective cohort studies because they follow individuals before the onset of disease, allowing for studies that can identify biomarkers and disease-modifying effects, and thereby contributing to systems epidemiology. Participants: This paper describes the design and baseline characteristics of an intensively examined subpopulation of the LifeLines cohort in the Netherlands. In this unique subcohort, LifeLines DEEP, we included 1539 part...

  20. Epidemiological and Clinical Baseline Characteristics as Predictive Biomarkers of Response to Anti-VEGF Treatment in Patients with Neovascular AMD

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    Miltiadis K. Tsilimbaris

    2016-01-01

    Full Text Available Purpose. To review the current literature investigating patient response to antivascular endothelial growth factor-A (VEGF therapy in the treatment of neovascular age-related macular degeneration (nAMD and to identify baseline characteristics that might predict response. Method. A literature search of the PubMed database was performed, using the keywords: AMD, anti-VEGF, biomarker, optical coherence tomography, treatment outcome, and predictor. The search was limited to articles published from 2006 to date. Exclusion criteria included phase 1 trials, case reports, studies focusing on indications other than nAMD, and oncology. Results. A total of 1467 articles were identified, of which 845 were excluded. Of the 622 remaining references, 47 met all the search criteria and were included in this review. Conclusion. Several baseline characteristics correlated with anti-VEGF treatment response, including best-corrected visual acuity, age, lesion size, and retinal thickness. The majority of factors were associated with disease duration, suggesting that longer disease duration before treatment results in worse treatment outcomes. This highlights the need for early treatment for patients with nAMD to gain optimal treatment outcomes. Many of the identified baseline characteristics are interconnected and cannot be evaluated in isolation; therefore multivariate analyses will be required to determine any specific relationship with treatment response.

  1. Baseline characteristics of patients in the Reduction of Events with Darbepoetin alfa in Heart Failure trial (RED-HF)

    Science.gov (United States)

    McMurray, John J.V.; Anand, Inder S.; Diaz, Rafael; Maggioni, Aldo P.; O'Connor, Christopher; Pfeffer, Marc A.; Solomon, Scott D.; Tendera, Michal; van Veldhuisen, Dirk J.; Albizem, Moetaz; Cheng, Sunfa; Scarlata, Debra; Swedberg, Karl; Young, James B.; Amuchastegui, M.; Belziti, C.; Bluguermann, J.; Caccavo, M.; Cartasegna, L.; Colque, R.; Cuneo, C.; Fernandez, A.; Gabito, A.; Goicochea, R.; Gonzalez, M.; Gorosito, V.; Grinfeld, L.; Hominal, M.; Kevorkian, R.; Litvak Bruno, M.; Llanos, J.; Mackinnon, I.; Manuale, O.; Marzetti, E.; Nul, D.; Perna, E.; Riccitelli, M.; Sanchez, A.; Santos, D.; Schygiel, P.; Toblli, J.; Vogel, D.; Aggarwal, A.; Amerena, J.; De Looze, F.; Fletcher, P.; Hare, D.; Ireland, M.; Krum, H.; Lattimore, J.; Marwick, T.; Sindone, A.; Thompson, P.; Waites, J.; Altenberger, J.; Ebner, C.; Lenz, K.; Pacher, R.; Poelzl, G.; Charlier, F.; de Ceuninck, M.; De Keulenaer, G.; Dendale, P.; Maréchal, P.; Mullens, W.; Thoeng, J.; Vanderheyden, M.; Vanhaecke, J.; Weytjens, C.; Wollaert, B.; Albuquerque, D.; Almeida, D.; Aspe y Rosas, J.; Bocchi, E.; Bordignon, S.; Clausell, N.; Kaiser, S.; Leaes, P.; Martins Alves, S.; Montera, M.; Moura, L.; Pereira de Castro, R.; Rassi, S.; Reis, A.; Saraiva, J.; Simões, M.; Souza Neto, J.; Teixeira, M.; Benov, H.; Chompalova, B.; Donova, T.; Georgiev, P.; Gotchev, D.; Goudev, A.; Grigorov, M.; Guenova, D.; Hergeldjieva, V.; Ivanov, D.; Kostova, E.; Manolova, A.; Marchev, S.; Nikolov, F.; Popov, A.; Raev, D.; Tzekova, M.; Czarnecki, W.; Giannetti, N.; Haddad, H.; Heath, J.; Huynh, T.; Lepage, S.; Liu, P.; Lonn, E.; Ma, P.; Manyari, D.; Moe, G.; Parker, J.; Pesant, Y.; Rajda, M.; Ricci, J.; Roth, S.; Sestier, F.; Sluzar, V.; Sussex, B.; Vizel, S.; Antezana, G.; Bugueno, C.; Castro, P.; Conejeros, C.; Manriquez, L.; Martinez, D.; Potthoff, S.; Stockins, B.; Vukasovic, J.; Gregor, P.; Herold, M.; Jerabek, O.; Jirmar, R.; Kuchar, R.; Linhart, A.; Podzemska, B.; Soucek, M.; Spac, J.; Spacek, R.; Vodnansky, P.; Bronnum-Schou, J.; Clemmensen, K.; Egstrup, K.; Jensen, G.; Kjoller-Hansen, L.; Kober, L.; Markenvard, J.; Rokkedal, J.; Skagen, K.; Torp-Pedersen, C.; Tuxen, C.; Videbak, L.; Laks, T.; Vahula, V.; Harjola, V.; Kettunen, R.; Kotila, M.; Bauer, F.; Cohen Solal, A.; Coisne, D.; Davy, J.; De Groote, P.; Dos Santos, P.; Funck, F.; Galinier, M.; Gibelin, P.; Isnard, R.; Neuder, Y.; Roul, G.; Sabatier, R.; Trochu, J.; Anker, S.; Denny, S.; Dreykluft, T.; Flesch, M.; Genth-Zotz, S.; Hambrecht, R.; Hein, J.; Jeserich, M.; John, M.; Kreider-Stempfle, H.; Laufs, U.; Muellerleile, K.; Natour, M.; Sandri, M.; Schäufele, T.; von Hodenberg, E.; Weyland, K.; Winkelmann, B.; Tse, H.; Yan, B.; Barsi, B.; Csikasz, J.; Dezsi, C.; Edes, I.; Forster, T.; Karpati, P.; Kerekes, C.; Kis, E.; Kosa, I.; Lupkovics, G.; Nagy, A.; Preda, I.; Ronaszeki, A.; Tomcsanyi, J.; Zamolyi, K.; Agarwal, D.; Bahl, V.; Bordoloi, A.; Chockalingam, K.; Chopda, M.; Chopra, V.; Dugal, J.; Ghaisas, N.; Ghosh, S.; Grant, P.; Hiremath, S.; Iyengar, S.; Jagadeesa Subramania, B.; Jain, P.; Joshi, A.; Khan, A.; Mullasari, A.; Naik, S.; Oomman, A.; Pai, V.; Pareppally Gopal, R.; Parikh, K.; Patel, T.; Prakash, V.; Sastry, B.; Sathe, S.; Sinha, N.; Srikanthan, V.; Subburamakrishnan, P.; Thacker, H.; Wander, G.; Admon, D.; Katz, A.; Klainman, E.; Lewis, B.; Marmor, A.; Moriel, M.; Mosseri, M.; Shotan, A.; Weinstein, J.; Zimlichman, R.; Agostoni, P.; Albanese, M.; Alunni, G.; Bini, R.; Boccanelli, A.; Bolognese, L.; Campana, C.; Carbonieri, E.; Carpino, C.; Checco, L.; Cosmi, F.; D'Angelo, G.; De Cristofaro, M.; Floresta, A.; Fucili, A.; Galvani, M.; Ivleva, A.; Marra, S.; Musca, G.; Peccerillo, N.; Perrone Filardi, P.; Picchio, E.; Russo, T.; Scelsi, L.; Senni, M.; Tavazzi, L.; Erglis, A.; Jasinkevica, I.; Kakurina, N.; Veze, I.; Volans, E.; Bagdonas, A.; Berukstis, E.; Celutkiene, J.; Dambrauskaite, A.; Jarasuniene, D.; Luksiene, D.; Rudys, A.; Sakalyte, G.; Sliaziene, S.; Aguilar-Romero, R.; Cardona-Muñoz, E.; Castro-Jimenez, J.; Chavez-Herrera, J.; Chuquiure Valenzuela, E.; De la Pena, G.; Herrera, E.; Leiva-Pons, J.; Lopez Alvarado, A.; Mendez Machado, G.; Ramos-Lopez, G.; Basart, D.; Buijs, E.; Cornel, J.; de Leeuw, M.; Dijkgraaf, R.; Dunselman, P.; Freericks, M.; Hamraoui, K.; Lenderlink, T.; Linssen, G.; Lodewick, P.; Lodewijks, C.; Lok, D.; Nierop, P.; Ronner, E.; Somsen, A.; van Dantzig, J.; van der Burgh, P.; van Kempen, L.; van Vlies, B.; Voors, A.; Wardeh, A.; Willems, F.; Dickstein, K.; Gundersen, T.; Hole, T.; Thalamus, J.; Westheim, A.; Dabrowski, M.; Gorski, J.; Korewicki, J.; Kuc, K.; Miekus, P.; Musial, W.; Niegowska, J.; Piotrowski, W.; Podolec, P.; Polonski, L.; Ponikowski, P.; Rynkiewicz, A.; Szelemej, R.; Trusz-Gluza, M.; Ujda, M.; Wojciechowski, D; Wysokinski, A.; Camacho, A.; Fonseca, C.; Monteiro, P.; Apetrei, E.; Bruckner, I.; Carasca, E.; Coman, I.; Datcu, M.; Dragulescu, S.; Ionescu, P.; Iordachescu-Petica, D.; Manitiu, I.; Popa, V.; Pop-Moldovan, A.; Radoi, M.; Stamate, S.; Tomescu, M.; Vita, I.; Aroutiounov, G.; Ballyuzek, M.; Bart, B.; Churina, S.; Glezer, M.; Goloshchekin, B.; Ivleva, A.; Kobalava, Z.; Kostenko, V.; Lopatin, Y.; Martynov, A.; Orlov, V.; Semernin, E.; Shogenov, Z.; Sidorenko, B.; Skvortsov, A.; Storzhakov, G.; Sulimov, V.; Talibov, O.; Tereshenko, S.; Tsyrline, V.; Zadionchenko, V.; Zateyshchikov, D.; Dzupina, A.; Hranai, M.; Kmec, J.; Micko, K.; Murin, J.; Pella, D.; Sojka, G.; Spisak, V.; Vahala, P.; Vinanska, D.; Badat, A.; Bayat, J.; Dawood, S.; Delport, E.; Ellis, G.; Garda, R.; Klug, E.; Mabin, T.; Naidoo, D.; Pretorius, M.; Ranjith, N.; Van Zyl, L.; Weich, H.; Anguita, M.; Berrazueta, J.; Bruguera i Cortada, J.; de Teresa, E.; Gómez Sánchez, M.; González Juanatey, J.; Gonzalez-Maqueda, I.; Jordana, R.; Lupon, J.; Manzano, L.; Pascual Figal, D.; Pulpón, L.; Recio, J.; Ridocci Soriano, F.; Rodríguez Lambert, J.; Roig Minguell, E.; Roig Minguell, E.; Romero, J.; Valdovinos, P.; Klintberg, L.; Kronvall, T.; Lycksell, M.; Morner, S.; Rydberg, E.; Swedberg, K.; Timberg, I.; Wikstrom, G.; Moccetti, T.4; Ashok, J.; Banerjee, P.; Carr-White, G.; Cleland, J.; Connolly, E.; Francis, M.; Greenbaum, R.; Kadr, H.; Lindsay, S.; McMurray, J.; Megarry, S.; Memon, A.; Murdoch, D.; Senior, R.; Squire, I.; Tan, L.; Witte, K.; Adams, K.; Adamson, P.; Adler, A.; Altschul, L.; Altschuller, A.; Amirani, H.; Anand, I.; Andreou, C.; Ansari, M.; Antonishen, M.; Banchs, H.; Banerjee, S.; Banish, D.; Bank, A.; Barbagelata, A.; Barnard, D.; Bellinger, R.; Benn, A.; Berk, M.; Berry, B.; Bethala, V.; Bilazarian, S.; Bisognano, J.; Bleyer, F.; Blum, M.; Boehmer, J.; Bouchard, A.; Boyle, A.; Bozkurt, B.; Brown, C.; Burlew, B.; Burnham, K.; Butler, J.; Call, J.; Cambier, P.; Cappola, T.; Carlson, R.; Chandler, B.; Chandra, R.; Chandraratna, P.; Chernick, R.; Colan, D.; Colfer, H.; Colucci, W.; Connelly, T.; Costantini, O.; Dadkhah, S.; Dauber, I.; Davis, J.; Davis, S.; Denning, S.; Drazner, M.; Dunlap, S.; Egbujiobi, L.; Elkayam, U.; Elliott, J.; El-Shahawy, M.; Essandoh, L.; Ewald, G.; Fang, J.; Farhoud, H.; Felker, G.; Fernandez, J.; Festin, R.; Fishbein, G.; Florea, V.; Flores, E.; Floro, J.; Gabris, M.; Garg, M.; Gatewood, R.; Geller, M.; Ghali, J.; Ghumman, W.; Gibbs, G.; Gillespie, E.; Gilmore, R.; Gogia, H.; Goldberg, L.; Gradus-Pizlo, I.; Grainger, T.; Gudmundsson, G.; Gunawardena, D.; Gupta, D.; Hack, T.; Hall, S.; Hamroff, G.; Hankins, S.; Hanna, M.; Hargrove, J.; Haught, W.; Hauptman, P.; Hazelrigg, M.; Herzog, C.; Heywood, J.; Hill, T.; Hilton, T.; Hirsch, H.; Hunter, J.; Ibrahim, H.; Imburgia, M.; Iteld, B.; Jackson, B.; Jaffrani, N.; Jain, D.; Jain, A.; James, M.; Jimenez, J.; Johnson, E.; Kale, P.; Kaneshige, A.; Kapadia, S.; Karia, D.; Karlsberg, R.; Katholi, R.; Kerut, E.; Khoury, W.; Kipperman, R.; Klapholz, M.; Kosinski, E.; Kozinn, M.; Kraus, D.; Krueger, S.; Krum, H.; Kumar, S.; Lader, E.; Lee, C.; Levy, W.; Lewis, E.; Light-McGroary, K.; Loh, I.; Lombardi, W.; Machado, C.; Maislos, F.; Mancini, D.; Markus, T.; Mather, P.; McCants, K.; McGrew, F.; McLaurin, B.; McMillan, E.; McNamara, D.; Meyer, T.; Meymandi, S.; Miller, A.; Minami, E.; Modi, M.; Mody, F.; Mohanty, P.; Moscoso, R.; Moskowitz, R.; Moustafa, M.; Mullen, M.; Naz, T.; Noonan, T.; O'Brien, T.; Oellerich, W.; Oren, R.; Pamboukian, S.; Pereira, N.; Pitt, W.; Porter, C.; Prabhu, S.; Promisloff, S.; Ratkovec, R.; Richardson, R.; Ross, A.; Saleh, N.; Saltzberg, M.; Sarkar, S.; Schmedtje, J.; Schneider, R.; Schuyler, G.; Shanes, J.; Sharma, A.; Siegel, C.; Siegel, R.; Silber, D.; Singh, V.; Singh, N.; Singh, J.; Sklar, J.; Small, R.; Smith, A.; Smith, E.; Smith, E.; Smull, D.; Sotolongo, R.; Staniloae, C.; Stapleton, D.; Steele, P.; Stehlik, J.; Stein, M.; Tang, W.; Thadani, U.; Torre-Amoine, G.; Trichon, B.; Tsai, C.; Tummala, R.; Van Bakel, A.; Vicari, R.; Vijay, N.; Vijayaraghavan, K.; Vittorio, T.; Vossler, M.; Wagoner, L.; Wallis, D.; Ward, N.; Widmer, M.; Wight, J.; Wilkins, C.; Williams, C.; Williams, G.; Winchester, M.; Winkel, E.; Wittmer, B.; Wood, D.; Wormer, D.; Wright, R.; Xu, Z.; Yasin, M.; Zolty, R.

    2013-01-01

    Aims This report describes the baseline characteristics of patients in the Reduction of Events with Darbepoetin alfa in Heart Failure trial (RED-HF) which is testing the hypothesis that anaemia correction with darbepoetin alfa will reduce the composite endpoint of death from any cause or hospital admission for worsening heart failure, and improve other outcomes. Methods and results Key demographic, clinical, and laboratory findings, along with baseline treatment, are reported and compared with those of patients in other recent clinical trials in heart failure. Compared with other recent trials, RED-HF enrolled more elderly [mean age 70 (SD 11.4) years], female (41%), and black (9%) patients. RED-HF patients more often had diabetes (46%) and renal impairment (72% had an estimated glomerular filtration rate <60 mL/min/1.73 m2). Patients in RED-HF had heart failure of longer duration [5.3 (5.4) years], worse NYHA class (35% II, 63% III, and 2% IV), and more signs of congestion. Mean EF was 30% (6.8%). RED-HF patients were well treated at randomization, and pharmacological therapy at baseline was broadly similar to that of other recent trials, taking account of study-specific inclusion/exclusion criteria. Median (interquartile range) haemoglobin at baseline was 112 (106–117) g/L. Conclusion The anaemic patients enrolled in RED-HF were older, moderately to markedly symptomatic, and had extensive co-morbidity. PMID:23329651

  2. Risk scores for diabetes and impaired glycaemia in the Middle East and North Africa

    DEFF Research Database (Denmark)

    Handlos, Line Neerup; Witte, Daniel Rinse; Almdal, Thomas Peter;

    2013-01-01

    AIMS: To develop risk scores for diabetes and diabetes or impaired glycaemia for individuals living in the Middle East and North Africa region. In addition, to derive national risk scores for Algeria, Saudi Arabia and the United Arab Emirates and to compare the performance of the regional risk...... between 50% and 57%. The regional and the national risk scores performed equally well in the three national samples. CONCLUSIONS: Two regional risk scores for diabetes and diabetes or impaired glycaemia applicable to the Middle East and North Africa region were identified. The regional risk scores...

  3. A Prospective Study of Pravastatin in the Elderly at Risk (PROSPER): Screening Experience and Baseline Characteristics.

    LENUS (Irish Health Repository)

    Ford, Ian

    2002-05-20

    BACKGROUND: PROSPER was designed to investigate the benefits of treatment with pravastatin in elderly patients for whom a typical doctor might consider the prescription of statin therapy to be a realistic option. METHODS: The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER) is a randomised, double blind, placebo-controlled trial to test the hypothesis that treatment with pravastatin (40 mg\\/day) will reduce the risk of coronary heart disease death, non-fatal myocardial infarction, and fatal or non-fatal stroke in elderly men and women with pre-existing vascular disease or with significant risk of developing this condition. RESULTS: In Scotland, Ireland, and the Netherlands, 23,770 individuals were screened, and 5,804 subjects (2,804 men and 3,000 women), aged 70 to 82 years (average 75 years) and with baseline cholesterol 4.0-9.0 mmol\\/l, were randomised. Randomised subjects had similar distributions with respect to age, blood pressure, and body mass index when compared to the entire group of screenees, but had a higher prevalence of smoking, diabetes, hypertension, and a history of vascular disease. The average total cholesterol level at baseline was 5.4 mmol\\/l (men) and 6.0 mmol\\/l (women). CONCLUSIONS: Compared with previous prevention trials of cholesterol-lowering drugs, the PROSPER cohort is significantly older and for the first time includes a majority of women. The study, having achieved its initial goal of recruiting more than 5,500 elderly high-risk men and women, aims to complete all final subject follow-up visits in the first half of 2002 with the main results being available in the fourth quarter of 2002.

  4. A Prospective Study of Pravastatin in the Elderly at Risk (PROSPER: Screening Experience and Baseline Characteristics

    Directory of Open Access Journals (Sweden)

    Lagaay A Margot

    2002-05-01

    Full Text Available Abstract Background PROSPER was designed to investigate the benefits of treatment with pravastatin in elderly patients for whom a typical doctor might consider the prescription of statin therapy to be a realistic option. Methods The PROspective Study of Pravastatin in the Elderly at Risk (PROSPER is a randomised, double blind, placebo-controlled trial to test the hypothesis that treatment with pravastatin (40 mg/day will reduce the risk of coronary heart disease death, non-fatal myocardial infarction, and fatal or non-fatal stroke in elderly men and women with pre-existing vascular disease or with significant risk of developing this condition. Results In Scotland, Ireland, and the Netherlands, 23,770 individuals were screened, and 5,804 subjects (2,804 men and 3,000 women, aged 70 to 82 years (average 75 years and with baseline cholesterol 4.0–9.0 mmol/l, were randomised. Randomised subjects had similar distributions with respect to age, blood pressure, and body mass index when compared to the entire group of screenees, but had a higher prevalence of smoking, diabetes, hypertension, and a history of vascular disease. The average total cholesterol level at baseline was 5.4 mmol/l (men and 6.0 mmol/l (women. Conclusions Compared with previous prevention trials of cholesterol-lowering drugs, the PROSPER cohort is significantly older and for the first time includes a majority of women. The study, having achieved its initial goal of recruiting more than 5,500 elderly high-risk men and women, aims to complete all final subject follow-up visits in the first half of 2002 with the main results being available in the fourth quarter of 2002.

  5. Baseline characteristics in the Bardoxolone methyl EvAluation in patients with Chronic kidney disease and type 2 diabetes mellitus

    DEFF Research Database (Denmark)

    Lambers Heerspink, Hiddo J; Chertow, Glenn M; Akizawa, Tadao;

    2013-01-01

    Type 2 diabetes mellitus (T2DM) is the most important contributing cause of end-stage renal disease (ESRD) worldwide. Bardoxolone methyl, a nuclear factor-erythroid-2-related factor 2 activator, augments estimated glomerular filtration. The Bardoxolone methyl EvAluation in patients with Chronic k...... kidney disease and type 2 diabetes mellitus: the Occurrence of renal eveNts (BEACON) trial was designed to establish whether bardoxolone methyl slows or prevents progression to ESRD. Herein, we describe baseline characteristics of the BEACON population....

  6. Characteristics of Treatment Seeking Finnish Pathological Gamblers: Baseline Data from a Treatment Study

    Science.gov (United States)

    Lahti, Tuuli; Halme, Jukka; Pankakoski, Maiju; Sinclair, David; Alho, Hannu

    2013-01-01

    This article describes the socio-demographic characteristics and gambling behavior of 39 pathological gamblers who participated in our treatment study in 2009. The inclusion criteria of the study were: score of five or more on both the South Oaks Gambling Screen (SOGS) and a pathological gambling screen based on the Diagnostic and Statistical…

  7. The Personalized Reminder Information and Social Management System (PRISM) Trial: Rationale, Methods and Baseline Characteristics

    Science.gov (United States)

    Czaja, Sara J.; Boot, Walter R.; Charness, Neil; Rogers, Wendy; Sharit, Joseph; Fisk, Arthur D.; Lee, Chin Chin; Nair, Sankaran N.

    2014-01-01

    Technology holds promise in terms of providing support to older adults. To date there have been limited robust systematic efforts to evaluate the psychosocial benefits of technology for older people and identify factors that influence both the usability and uptake of technology systems. In response to these issues we developed the Personal Reminder Information and Social Management System (PRISM), a software application designed for older adults to support social connectivity, memory, knowledge about topics, leisure activities and access to resources. This trail is evaluating the impact of access to the PRISM system on outcomes such as social isolation, social support and connectivity. This paper reports on the approach used to design the PRISM system, study design, methodology and baseline data for the trial. The trial is multi-site randomized field trial. PRISM is being compared to a Binder condition where participants received a binder that contained content similar to that found on PRISM. The sample includes 300 older adults, aged 65 – 98 years, who lived alone and at risk for being isolated. The primary outcome measures for the trial include indices of social isolation and support and well-being. Secondary outcomes measures include indices of computer proficiency, technology uptake and attitudes towards technology. Follow-up assessments occurred at 6 and 12 months post-randomization. The results of this study will yield important information about the potential value of technology for older adults. The study also demonstrates how a user-centered iterative design approach can be incorporated into the design and evaluation of an intervention protocol. PMID:25460342

  8. VALsartan In Acute myocardial iNfarcTion (VALIANT) trial: baseline characteristics in context

    DEFF Research Database (Denmark)

    Velazquez, Eric J; Pfeffer, Marc A; McMurray, John V;

    2003-01-01

    BACKGROUND: The VALsartan In Acute myocardial iNfarcTion (VALIANT) trial compared outcomes with: (1) angiotensin-converting enzyme inhibition (ACEI) with the reference agent captopril; (2) angiotensin-receptor blockade (ARB) with valsartan; or (3) both in patients with heart failure (HF) and....../or left ventricular systolic dysfunction (LVSD) after myocardial infarction (MI). AIMS: a goal of this active-control trial was to simulate conditions that would lead current practitioners to use ACEIs. Thus, we compared characteristics of VALIANT patients with those of patients in placebo...... at enrollment. Most (72%) had Killip class>/=II HF. Patients received evidence-based therapies at rates similar to those of contemporary MI trials and at an improved rate compared with prior placebo-controlled ACEI trials. CONCLUSION: VALIANT represents the largest globally representative cohort enrolled...

  9. Living with diabetes: rationale, study design and baseline characteristics for an Australian prospective cohort study

    Directory of Open Access Journals (Sweden)

    Donald Maria

    2012-01-01

    Full Text Available Abstract Background Diabetes mellitus is a major global public health threat. In Australia, as elsewhere, it is responsible for a sizeable portion of the overall burden of disease, and significant costs. The psychological and social impact of diabetes on individuals with the disease can be severe, and if not adequately addressed, can lead to the worsening of the overall disease picture. The Living With Diabetes Study aims to contribute to a holistic understanding of the psychological and social aspects of diabetes mellitus. Methods/Design The Living With Diabetes Study is a 5-year prospective cohort study, based in Queensland, Australia. The first wave of data, which was collected via a mailed self-report survey, was gathered in 2008, with annual collections thereafter. Measurements include: demographic, lifestyle, health and disease characteristics; quality of life (EQ-5D, ADDQoL; emotional well-being (CES-D, LOT-R, ESSI; disease self-management (PAM; and health-care utilisation and patient-assessed quality of care (PACIC. 29% of the 14,439 adults who were invited to participate in the study agreed to do so, yielding a sample size of 3,951 people. Discussion The data collected by the Living With Diabetes Study provides a good representation of Australians with diabetes to follow over time in order to better understand the natural course of the illness. The study has potential to further illuminate, and give a comprehensive picture of the psychosocial implications of living with diabetes. Data collection is ongoing.

  10. ALS Multicenter Cohort Study of Oxidative Stress (ALS COSMOS): The study methodology, recruitment, and baseline demographic and disease characteristics

    Science.gov (United States)

    Mitsumoto, Hiroshi; Factor-Litvak, Pam; Andrews, Howard; Goetz, Raymond R.; Andrews, Leslie; Rabkin, Judith G.; McElhiney, Martin; Nieves, Jeri; Santella, Regina M.; Murphy, Jennifer; Hupf, Jonathan; Singleton, Jess; Merle, David; Kilty, Mary; Heitzman, Daragh; Bedlack, Richard S.; Miller, Robert G; Katz, Jonathan S.; Forshew, Dallas; Barohn, Richard J.; Sorenson, Eric J.; Oskarsson, Bjorn; Filho, J Americo M. Fernandes; Kasarskis, Edward J.; Lomen-Hoerth, Catherine; Mozaffar, Tahseen; Rollins, Yvonne D.; Nations, Sharon P.; Swenson, Andrea J.; Shefner, Jeremy M.; Andrews, Jinsy A.; Koczon-Jaremko, Boguslawa A.

    2015-01-01

    Objective In a multicenter study of newly diagnosed ALS patients without a reported family history of ALS, we are prospectively investigating whether markers of oxidative stress (OS) are associated with disease progression. Methods An extensive structured telephone interview ascertained environmental, lifestyle, dietary and psychological risk factors associated with OS. Detailed assessments were performed at baseline and at 3 to 6 month intervals during the ensuing 30 months. Our biorepository includes DNA, plasma, urine, and skin. Results 355 patients were recruited. Subjects were enrolled over a 36 month-period at 16 sites. To meet the target number of subjects, the recruitment period was prolonged and additional sites were included. Demographic and disease characteristics were similar between 477 eligible/non-enrolled and enrolled patients, with the only difference being type of health insurance among enrolled patients. Sites were divided into 3 groups by the number of enrolled subjects. Comparing these 3 groups, the Columbia site had fewer “definite ALS” diagnoses. Conclusion This is the first prospective, interdisciplinary, in-depth, multicenter epidemiological investigation of OS related to ALS progression and was accomplished by an aggressive recruitment process. The baseline demographic and disease features of the study sample are now fully characterized. PMID:24564738

  11. Baseline characteristics of the 4011 patients recruited into the ‘Efficacy of Nitric Oxide in Stroke’ (ENOS) trial

    DEFF Research Database (Denmark)

    2014-01-01

    -stroke antihypertensive therapy are each safe and effective. METHODS: This study is an international multi-centre prospective randomized single-blind blinded-endpoint parallel-group partial-factorial controlled trial of transdermal glyceryl trinitrate(a nitric oxide donor, given for seven-days) vs. no glyceryl trinitrate......, and of continuing vs. stopping (temporarily for seven-days) pre-stroke antihypertensive drugs if relevant, inpatients with acute ischaemic stroke or intracerebral haemorrhage and high systolic blood pressure (140–220 mmHg). RESULTS: Recruitment ran from July 2001 to October 2013. Four thousand eleven...... patients [2097 (52·3%) in the continue/stop arm] were recruited from 173 sites across 23 countries in 5 continents (Asia 14%, Continental Europe 16%, UK 64%). Baseline characteristics include: mean age 70 (standard deviation 12) years; male 57%; mean time from stroke to recruitment 26 (13) h; mean severity...

  12. Effect of atorvastatin on glycaemia progression in patients with diabetes: an analysis from the Collaborative Atorvastatin in Diabetes Trial (CARDS)

    OpenAIRE

    Livingstone, Shona J.; Looker, Helen C.; Akbar, Tahira; Betteridge, D. John; Durrington, Paul N.; Hitman, Graham A.; Neil, H Andrew W; Fuller, John H.; Colhoun, Helen M.

    2015-01-01

    Aims/hypothesis In an individual-level analysis we examined the effect of atorvastatin on glycaemia progression in type 2 diabetes and whether glycaemia effects reduce the prevention of cardiovascular disease (CVD) with atorvastatin. Methods The study population comprised 2,739 people taking part in the Collaborative Atorvastatin Diabetes Study (CARDS) who were randomised to receive atorvastatin 10 mg or placebo and who had post-randomisation HbA1c data. This secondary analysis used Cox regre...

  13. Effects of Aerobic Exercise and Whole Body Vibration on Glycaemia Control in Type 2 Diabetic Males

    OpenAIRE

    Mahyar Salavati; Hamid Aghaalinejad; Lale Behboudi; Mohammad-Ali Azarbayjani

    2011-01-01

    Purpose aerobic exercise has been identified as the main treatment for type 2 diabetic patients. Such an exercise, however, is usually repined by some of patients who suffer from lack of stamina. Therefore, whole body vibration has recently been introduced as a passive intervention. The present study aimed at comparing how aerobic exercise and whole body vibration affect glycaemia control in type 2 diabetic males. Methods Thirty diabetic males were divided into three groups, namely aerobic ex...

  14. Glycaemic control: The role of nutritional intake, postprandial glycaemia, nutrition therapy adherence, and diabetes complications

    OpenAIRE

    Pinto, Ezequiel

    2014-01-01

    This thesis analysed the associations between several clinical and psychometric variables that can determine glycaemic control: nutritional intake, barriers to nutrition therapy adherence, postprandial glycaemia, and diabetes complications perception. A group of 66 patients previously diagnosed with type 2 diabetes mellitus was recruited and categorized into patients with HbA1c below 7% (proper glycaemic control) and patients with HbA1c of 7% or above (poor glycaemic control). All subje...

  15. Fenofibrate Intervention and Event Lowering in Diabetes (FIELD study: baseline characteristics and short-term effects of fenofibrate [ISRCTN64783481

    Directory of Open Access Journals (Sweden)

    2005-08-01

    Full Text Available Abstract Objective The Fenofibrate Intervention and Event Lowering in Diabetes (FIELD Study is examining the effects of long-term fibrate therapy on coronary heart disease (CHD event rates in patients with diabetes mellitus. This article describes the trial's run-in phase and patients' baseline characteristics. Research design and methods FIELD is a double-blind, placebo-controlled trial in 63 centres in 3 countries evaluating the effects of fenofibrate versus placebo on CHD morbidity and mortality in 9795 patients with type 2 diabetes mellitus. Patients were to have no indication for lipid-lowering therapy on randomization, but could start these or other drugs at any time after randomization. Follow-up in the study was to be for a median duration of not less than 5 years and until 500 major coronary events (fatal coronary heart disease plus nonfatal myocardial infarction had occurred. Results About 2100 patients (22% had some manifestation of cardiovascular disease (CVD at baseline and thus high risk status. Less than 25% of patients without CVD had a (UKPDS determined calculated 5-year CHD risk of 30, most were men, two-thirds were aged over 60 years, and substantial proportions had NCEP ATP III features of the metabolic syndrome independent of their diabetes, including low HDL (60%, high blood pressure measurement or treatment for hypertension (84%, high waist measurement (68%, and raised triglycerides (52%. After a 6-week run-in period before randomisation with all participants receiving 200 mg comicronized fenofibrate, there were declines in total and LDL cholesterol (10% and triglycerides (26% and an increase in HDL cholesterol (6.5%. Conclusion The study will show the effect of PPAR-alpha agonist action on CHD and other vascular outcomes in patients with type 2 diabetes including substantial numbers with low to moderate CVD risk but with the various components of the metabolic syndrome. The main results of the study will be reported in

  16. Baseline characteristics of participants in the VITamin D and OmegA-3 TriaL (VITAL).

    Science.gov (United States)

    Bassuk, Shari S; Manson, JoAnn E; Lee, I-Min; Cook, Nancy R; Christen, William G; Bubes, Vadim Y; Gordon, David S; Copeland, Trisha; Friedenberg, Georgina; D'Agostino, Denise M; Ridge, Claire Y; MacFadyen, Jean G; Kalan, Kate; Buring, Julie E

    2016-03-01

    Evidence for a role of supplemental vitamin D and marine omega-3 fatty acids in preventing cancer and cardiovascular disease (CVD) remains inconclusive and insufficient to inform nutritional recommendations for primary prevention. The VITamin D and Omega-A 3 TriaL (VITAL) is an ongoing nationwide, randomized, double-blind, placebo-controlled clinical trial designed to fill this knowledge gap. The study population consists of 25,874 U.S. adults without cancer or CVD at baseline, who were selected only on age (men aged ≥50 and women aged ≥55), with an oversampling of African Americans (n=5,107). In a 2×2 factorial design, participants were randomized to one of four supplement groups: [1] active vitamin D3 (cholecalciferol; 2000IU/d) and active marine omega-3 fatty acids (Omacor® fish oil, eicosapentaenoic acid [EPA] and docosahexaenoic acid [DHA], 1g/d); [2] active vitamin D and omega-3 placebo; [3] vitamin D placebo and active marine omega-3 fatty acids; or [4] vitamin D placebo and omega-3 placebo. The mean length of the randomized treatment period will be 5years. The randomization was successful, as evidenced by similar distributions of baseline demographic, health, and behavioral characteristics across treatment groups. The similar distribution of known potential confounders across treatment groups strongly suggests that unmeasured or unknown potential confounders are also equally distributed. VITAL is expected to provide important information on the benefit-risk balance of vitamin D and omega-3 fatty acid supplementation when taken for the primary prevention of cancer and CVD. PMID:26767629

  17. Prevalence of Comorbidities and Baseline Characteristics of LAP-BAND AP® Subjects in the Helping Evaluate Reduction in Obesity (HERO) Study

    OpenAIRE

    Dreyer, Nancy; Dixon, John B.; Okerson, Ted; Finkelstein, Eric A.; Globe, Denise

    2013-01-01

    Objective To describe the baseline characteristics in patients who chose placement of a LAP-BAND AP® System (LBAP) and participated in the Helping Evaluate Reduction in Obesity (HERO) Study across regions. Patients and Methods HERO is a five- year, prospective, multicenter, international study of patients with LBAP placement between July 22, 2009 and January 31, 2011. In addition to baseline and peri-surgery clinical data, seven follow up visits are scheduled at 3, 6 and 12 months, and annual...

  18. A randomised controlled trial of forward-planned radiotherapy (IMRT) for early breast cancer: Baseline characteristics and dosimetry results

    International Nuclear Information System (INIS)

    Background and purpose: This large trial was designed to investigate whether correction of dose inhomogeneities using intensity-modulated radiotherapy (IMRT) reduces late toxicity and improves quality of life in patients with early breast cancer. This paper reports baseline characteristics of trial participants and dosimetry results. Materials and methods: Standard tangential plans of 1145 trials were analysed. Patients with inhomogeneous plans, defined by ICRU recommendations, were randomised to forward-planned IMRT or standard radiotherapy. Results: Twenty-nine percentage of patients had adequate dosimetry with standard 2D radiotherapy. In the randomised patients, the decreases in mean volumes receiving greater than 107% (Vol > 107) and less than 95% (Vol 3 (95% CI 26.4-41.6; P 3 (95% CI 34.4-61.9; P 107 > 2 cm3 on standard radiotherapy plans. Conclusion: This large trial, in which patients with all breast sizes were eligible, confirmed that breast dosimetry can be significantly improved with a simple method of forward-planned IMRT and has little impact on radiotherapy resources. It is shown that patients with larger breasts are more likely to have dose inhomogeneities and breast separation gives some indication of this likelihood. Photographic assessment of patients at 2 years after radiotherapy, as the next part of this randomised controlled trial, will show whether these results for IMRT translate into improved cosmetic outcome in patients with early breast cancer. This would provide impetus for the widespread adoption of 3D planning and IMRT.

  19. Indirect comparisons of second-generation tyrosine kinase inhibitors in CML: case study using baseline population characteristics

    Directory of Open Access Journals (Sweden)

    Kimbach Tran Carpiuc

    2010-10-01

    Full Text Available Kimbach Tran Carpiuc1, Gianantonio Rosti2, Fausto Castagnetti2, Maarten Treur3, Jennifer Stephens11Pharmerit North America LLC, Bethesda, MD, USA; 2Department of Hematology and Oncology, S Orsola-Malpighi University Hospital, Bologna, Italy; 3Pharmerit Europe, Rotterdam, The NetherlandsAbstract: The use of indirect comparisons to evaluate the relative effectiveness between two or more treatments is widespread in the literature and continues to grow each year. Appropriate methodologies will be essential for integrating data from various published clinical trials into a systematic framework as part of the increasing emphasis on comparative effectiveness research. This article provides a case study example for clinicians using the baseline study population characteristics and response rates of the tyrosine kinase inhibitors in imatinib-resistant or imatinib-intolerant chronic myelogenous leukemia followed by a discussion of indirect comparison methods that are being increasingly implemented to address challenges with these types of comparisons.Keywords: comparative effectiveness research, meta-analysis, BCR–ABL-positive chronic myelogenous leukemia, imatinib mesylate, nilotinib, dasatinib 

  20. Baseline participant characteristics and risk for dropout from ten obesity randomized controlled trials: a pooled analysis of individual level data

    Directory of Open Access Journals (Sweden)

    Kathryn Ann Kaiser

    2014-12-01

    Full Text Available Introduction: Understanding participant demographic characteristics that inform the optimal design of obesity RCTs have been examined in few studies. The objective of this study was to investigate the association of individual participant characteristics and dropout rates (DORs in obesity randomized controlled trials (RCT by pooling data from several publicly available datasets for analyses. We comprehensively characterize DORs and patterns in obesity RCTs at the individual study level, and describe how such rates and patterns vary as a function of individual-level characteristics. Methods: We obtained and analyzed nine publicly-available, obesity RCT datasets that examined weight loss or weight gain prevention as a primary or secondary endpoint. Four risk factors for dropout were examined by Cox proportional hazards including sex, age, baseline BMI, and race/ethnicity. The individual study data were pooled in the final analyses with a random effect for study, and HR and 95% CIs were computed. Results: Results of the multivariate analysis indicated that the risk of dropout was significantly higher for females compared to males (HR= 1.24, 95% CI = 1.05, 1.46. Hispanics and Non-Hispanic blacks had a significantly higher dropout rate compared to non-Hispanic whites (HR= 1.62, 95% CI = 1.37, 1.91; HR= 1.22, 95% CI = 1.11, 1.35, respectively. There was a significantly increased risk of dropout associated with advancing age (HR= 1.02, 95% CI = 1.01, 1.02 and increasing BMI (HR= 1.03, 95% CI = 1.03, 1.04. Conclusion/Significance: As more studies may focus on special populations, researchers designing obesity RCTs may wish to oversample in certain demographic groups if attempting to match comparison groups based on generalized estimates of expected dropout rates, or otherwise adjust a priori power estimates. Understanding true reasons for dropout may require additional methods of data gathering not generally employed in obesity RCTs, e.g. time on

  1. A cluster randomized trial of routine HIV-1 viral load monitoring in Zambia: study design, implementation, and baseline cohort characteristics.

    Directory of Open Access Journals (Sweden)

    John R Koethe

    Full Text Available BACKGROUND: The benefit of routine HIV-1 viral load (VL monitoring of patients on antiretroviral therapy (ART in resource-constrained settings is uncertain because of the high costs associated with the test and the limited treatment options. We designed a cluster randomized controlled trial to compare the use of routine VL testing at ART-initiation and at 3, 6, 12, and 18 months, versus our local standard of care (which uses immunological and clinical criteria to diagnose treatment failure, with discretionary VL testing when the two do not agree. METHODOLOGY: Dedicated study personnel were integrated into public-sector ART clinics. We collected participant information in a dedicated research database. Twelve ART clinics in Lusaka, Zambia constituted the units of randomization. Study clinics were stratified into pairs according to matching criteria (historical mortality rate, size, and duration of operation to limit the effect of clustering, and independently randomized to the intervention and control arms. The study was powered to detect a 36% reduction in mortality at 18 months. PRINCIPAL FINDINGS: From December 2006 to May 2008, we completed enrollment of 1973 participants. Measured baseline characteristics did not differ significantly between the study arms. Enrollment was staggered by clinic pair and truncated at two matched sites. CONCLUSIONS: A large clinical trial of routing VL monitoring was successfully implemented in a dynamic and rapidly growing national ART program. Close collaboration with local health authorities and adequate reserve staff were critical to success. Randomized controlled trials such as this will likely prove valuable in determining long-term outcomes in resource-constrained settings. TRIAL REGISTRATION: Clinicaltrials.gov NCT00929604.

  2. Baseline characteristics of HIV & hepatitis B virus (HIV/HBV) co-infected patients from Kolkata, India

    Science.gov (United States)

    Sarkar, Jayeeta; Saha, Debraj; Bandyopadhyay, Bhaswati; Saha, Bibhuti; Kedia, Deepika; Guha Mazumder, D.N.; Chakravarty, Runu; Guha, Subhasish Kamal

    2016-01-01

    Background & objectives: Hepatitis B virus (HBV) and HIV co-infection has variable prevalence worldwide. In comparison to HBV mono-infection, the course of chronic HBV infection is accelerated in HIV/HBV co-infected patients. The present study was carried out to analyse the baseline characteristics (clinical, biochemical, serological and virological) of treatment naïve HIV/HBV co-infected and HIV mono-infected patients. Methods: Between July 2011 and January 2013, a total number of 1331 HIV-seropositive treatment naïve individuals, enrolled in the ART Centre of Calcutta School of Tropical Medicine, Kolkata, India, were screened for hepatitis B surface antigen (HBsAg). A total of 1253 HIV mono-infected and 78 HIV/HBV co-infected patients were characterized. The co-infected patients were evaluated for HBeAg and anti-HBe antibody by ELISA. HIV RNA was quantified for all co-infected patients. HBV DNA was detected and quantified by real time-PCR amplification followed by HBV genotype determination. Results: HIV/HBV co-infected patients had proportionately more advanced HIV disease (WHO clinical stage 3 and 4) than HIV mono-infected individuals (37.1 vs. 19.9%). The co-infected patients had significantly higher serum bilirubin, alanine aminotransferase (ALT), alkaline phosphatase and ALT/platelet ratio index (APRI). CD4 count was non-significantly lower in co-infected patients. Majority (61.5%) were HBeAg positive with higher HIV RNA (PHIV/HBV co-infected patients had significantly higher serum bilirubin, ALT, alkaline phosphatase and lower platelet count. HBeAg positive co-infected patients had higher HIV RNA and HBV DNA compared to HBeAg negative co-infected patients. Prior to initiation of antiretroviral treatment (ART) all patients should be screened for HBsAg to initiate appropriate ART regimen. PMID:27488008

  3. Baseline characteristics of patients with chronic kidney disease stage 3 and stage 4 in spain: the MERENA observational cohort study

    Directory of Open Access Journals (Sweden)

    Montes Rafael

    2011-10-01

    Full Text Available Abstract Background To obtain information on cardiovascular morbidity, hypertension control, anemia and mineral metabolism based on the analysis of the baseline characteristics of a large cohort of Spanish patients enrolled in an ongoing prospective, observational, multicenter study of patients with stages 3 and 4 chronic kidney diseases (CKD. Methods Multicenter study from Spanish government hospital-based Nephrology outpatient clinics involving 1129 patients with CKD stages 3 (n = 434 and 4 (n = 695 defined by GFR calculated by the MDRD formula. Additional analysis was performed with GFR calculated using the CKD-EPI and Cockcroft-Gault formula. Results In the cohort as a whole, median age 70.9 years, morbidity from all cardiovascular disease (CVD was very high (39.1%. In CKD stage 4, CVD prevalence was higher than in stage 3 (42.2 vs 35.6% p 300 mg/day was present in more than 60% of patients and there was no significant differences between stages 3 and 4 CKD (1.2 ± 1.8 and 1.3 ± 1.8 g/day, respectively. A majority of the patients had hemoglobin levels greater than 11 g/dL (91.1 and 85.5% in stages 3 and 4 CKD respectively p Conclusion This study provides an overview of key clinical parameters in patients with CKD Stages 3 and 4 where delivery or care was largely by nephrologists working in a network of hospital-based clinics of the Spanish National Healthcare System.

  4. Effects of PGX, a novel functional fibre, on acute and delayed postprandial glycaemia

    OpenAIRE

    Brand-Miller, J C; Atkinson, F S; Gahler, R J; Kacinik, V; Lyon, M R; Wood, S

    2010-01-01

    Background: Viscous fibre in food has established health benefits, but few functional fibre preparations are both effective and palatable. Our objective was to determine the most effective dose, formulation and timing of consumption of a novel fibre supplement (PolyGlycopleX (PGX)) in reducing postprandial glycaemia. Subjects/methods: Three trials were undertaken, each with 10 subjects (8M and 8F; age 24.4±2.6 years). Granular supplement was tested at four doses (0, 2.5, 5.0 and 7.5 g) with b...

  5. Design, baseline characteristics, and retention of African American light smokers into a randomized trial involving biological data

    Directory of Open Access Journals (Sweden)

    Okuyemi Kolawole S

    2011-01-01

    Full Text Available Abstract Background African Americans experience significant tobacco-related health disparities despite the fact that over half of African American smokers are light smokers (use ≤10 cigarettes per day. African Americans have been under-represented in smoking cessation research, and few studies have evaluated treatment for light smokers. This paper describes the study design, measures, and baseline characteristics from Kick It at Swope III (KIS-III, the first treatment study of bupropion for African American light smokers. Methods Five hundred forty African American light smokers were randomly assigned to receive bupropion (150mg bid (n = 270 or placebo (n = 270 for 7 weeks. All participants received written materials and health education counseling. Participants responded to survey items and provided blood samples for evaluation of phenotype and genotype of CYP2A6 and CYP2B6 enzymes involved in nicotine and bupropion metabolism. Primary outcome was cotinine-verified 7-day point prevalence smoking abstinence at Week 26 follow-up. Results Of 2,628 individuals screened, 540 were eligible, consented, and randomized to treatment. Participants had a mean age of 46.5 years and 66.1% were women. Participants smoked an average of 8.0 cigarettes per day, had a mean exhaled carbon monoxide of 16.4ppm (range 1-55 and a mean serum cotinine of 275.8ng/ml. The mean Fagerström Test for Nicotine Dependence was 3.2, and 72.2% of participants smoked within 30 minutes of waking. The average number of quit attempts in the past year was 3.7 and 24.2% reported using pharmacotherapy in their most recent quit attempt. Motivation and confidence to quit were high. Conclusion KIS-III is the first study designed to examine both nicotine and bupropion metabolism, evaluating CYP2A6 and CYP2B6 phenotype and genotype in conjunction with psychosocial factors, in the context of treatment of African American light smokers. Of 1629 smokers screened for study participation, only

  6. Postprandial Levels of Branch Chained and Aromatic Amino Acids Associate with Fasting Glycaemia.

    Science.gov (United States)

    Ottosson, Filip; Ericson, Ulrika; Almgren, Peter; Nilsson, Jeanette; Magnusson, Martin; Fernandez, Céline; Melander, Olle

    2016-01-01

    High fasting plasma concentrations of isoleucine, phenylalanine, and tyrosine have been associated with increased risk of hyperglycaemia and incidence of type 2 diabetes. Whether these associations are diet or metabolism driven is unknown. We examined how the dietary protein source affects the postprandial circulating profile of these three diabetes associated amino acids (DMAAs) and tested whether the postprandial DMAA profiles are associated with fasting glycaemia. We used a crossover design with twenty-one healthy individuals and four different isocaloric test meals, containing proteins from different dietary sources (dairy, fish, meat, and plants). Analysis of the postprandial DMAAs concentrations was performed using targeted mass spectrometry. A DMAA score was defined as the sum of all the three amino acid concentrations. The postprandial area under the curve (AUC) of all the three amino acids and the DMAA score was significantly greater after intake of the meal with dairy protein compared to intake of the three other meals. The postprandial AUC for the DMAA score and all the three amino acids strongly associated with fasting glucose level and insulin resistance. This indicates the importance of the postprandial kinetics and metabolism of DMAAs in understanding the overall association between DMAAs and glycaemia. PMID:27274867

  7. The Queensland study of Melanoma: Environmental and Genetic Associations (Q-MEGA). Study design, baseline characteristics, and repeatability of phenotype and sun exposure measures

    OpenAIRE

    Baxter, Amanda J.; Hughes, Maria Celia; Kvaskoff, Marina; Siskind, Victor; Shekar, Sri; Aitken, Joanne F.; Green, Adele C; Duffy, David L; Hayward, Nicholas K; Martin, Nicholas G; Whiteman, David C.

    2008-01-01

    Cutaneous malignant melanoma (CMM) is a major health issue in Queensland, Australia which has the world’s highest incidence. Recent molecular and epidemiologic studies suggest that CMM arises through multiple etiological pathways involving gene-environment interactions. Understanding the potential mechanisms leading to CMM requires larger studies than those previously conducted. This article describes the design and baseline characteristics of Q-MEGA, the Queensland study of Melanoma: Environ...

  8. Baseline characteristics, time-to-hospital admission and in-hospital outcomes of patients hospitalized with ST-segment elevation acute coronary syndromes, 2002 to 2005

    OpenAIRE

    Pehnec, Zlatko; Sinkovič, Andreja; Kamenik, Borut; Marinšek, Martin; Svenšek, Franci

    2009-01-01

    Objective. The purpose of this study was to retrospectively determine baseline patient characteristics, time-to-hospital admission, utilization of reperfusion therapy and outcomes of patients hospitalized with ST-segment elevation acute coronary syndromes (ACS) between 2002 and 2005, particularly after 24-h primary percutaneous coronary intervention (PCI) was introduced in 2004. Methods. Included were all patients admitted to the intensive care unit (ICU) from 2002 to 2005 who met the crit...

  9. The Clinical Research Center for Depression Study: Baseline Characteristics of a Korean Long-Term Hospital-Based Observational Collaborative Prospective Cohort Study

    OpenAIRE

    Kim, Tae-Suk; Jeong, Seung Hee; Kim, Jung-Bum; Lee, Min-Soo; Kim, Jae-Min; Yim, Hyeon-Woo; Jun, Tae-Youn

    2010-01-01

    Objective The Clinical Research Center for Depression (CRESCEND) study is a 9-year observational collaborative prospective cohort study for the clinical outcomes in participants with depressive disorders in Korea. In this study, we examined the baseline characteristics of the depressive participants as the hospital-based cohort. Methods Participants were assessed using various instruments including the Clinical Global Impression scale, 17-item Hamilton Depression Rating Scale (HDRS-17), Hamil...

  10. The COPE healthy lifestyles TEEN randomized controlled trial with culturally diverse high school adolescents: Baseline characteristics and methods

    OpenAIRE

    Melnyk, Bernadette Mazurek; Kelly, Stephanie; Jacobson, Diana; Belyea, Michael; Shaibi, Gabriel; Small, Leigh; O’Haver, Judith; Marsiglia, Flavio Francisco

    2013-01-01

    Obesity and mental health disorders remain significant public health problems in adolescents. Substantial health disparities exist with minority youth experiencing higher rates of these problems. Schools are an outstanding venue to provide teens with skills needed to improve their physical and mental health, and academic performance. In this paper, the authors describe the design, intervention, methods and baseline data for a randomized controlled trial with 779 culturally diverse high-school...

  11. Berries and anthocyanins: promising functional food ingredients with postprandial glycaemia-lowering effects.

    Science.gov (United States)

    Castro-Acosta, Monica L; Lenihan-Geels, Georgia N; Corpe, Christopher P; Hall, Wendy L

    2016-08-01

    The prevalence of type 2 diabetes (T2D) is predicted to reach unprecedented levels in the next few decades. In addition to excess body weight, there may be other overlapping dietary drivers of impaired glucose homeostasis that are associated with an obesogenic diet, such as regular exposure to postprandial spikes in blood glucose arising from diets dominated by highly refined starches and added sugars. Strategies to reduce postprandial hyperglycaemia by optimising the functionality of foods would strengthen efforts to reduce the risk of T2D. Berry bioactives, including anthocyanins, are recognised for their inhibitory effects on carbohydrate digestion and glucose absorption. Regular consumption of berries has been associated with a reduction in the risk of T2D. This review aims to examine the evidence from in vitro, animal and human studies, showing that berries and berry anthocyanins may act in the gut to modulate postprandial glycaemia. Specifically, berry extracts and anthocyanins inhibit the activities of pancreatic α-amylase and α-glucosidase in the gut lumen, and interact with intestinal sugar transporters, sodium-dependent glucose transporter 1 and GLUT2, to reduce the rate of glucose uptake into the circulation. Growing evidence from randomised controlled trials suggests that berry extracts, purées and nectars acutely inhibit postprandial glycaemia and insulinaemia following oral carbohydrate loads. Evidence to date presents a sound basis for exploring the potential for using berries/berry extracts as an additional stratagem to weight loss, adherence to dietary guidelines and increasing physical exercise, for the prevention of T2D. PMID:27170557

  12. Genotype-phenotype characteristics and baseline natural history of heritable neuropathies caused by mutations in the MPZ gene.

    Science.gov (United States)

    Sanmaneechai, Oranee; Feely, Shawna; Scherer, Steven S; Herrmann, David N; Burns, Joshua; Muntoni, Francesco; Li, Jun; Siskind, Carly E; Day, John W; Laura, Matilde; Sumner, Charlotte J; Lloyd, Thomas E; Ramchandren, Sindhu; Shy, Rosemary R; Grider, Tiffany; Bacon, Chelsea; Finkel, Richard S; Yum, Sabrina W; Moroni, Isabella; Piscosquito, Giuseppe; Pareyson, Davide; Reilly, Mary M; Shy, Michael E

    2015-11-01

    We aimed to characterize genotype-phenotype correlations and establish baseline clinical data for peripheral neuropathies caused by mutations in the myelin protein zero (MPZ) gene. MPZ mutations are the second leading cause of Charcot-Marie-Tooth disease type 1. Recent research makes clinical trials for patients with MPZ mutations a realistic possibility. However, the clinical severity varies with different mutations and natural history data on progression is sparse. We present cross-sectional data to begin to define the phenotypic spectrum and clinical baseline of patients with these mutations. A cohort of patients with MPZ gene mutations was identified in 13 centres of the Inherited Neuropathies Consortium - Rare Disease Clinical Research Consortium (INC-RDCRC) between 2009 and 2012 and at Wayne State University between 1996 and 2009. Patient phenotypes were quantified by the Charcot-Marie-Tooth disease neuropathy score version 1 or 2 and the Charcot-Marie-Tooth disease paediatric scale outcome instruments. Genetic testing was performed in all patients and/or in first- or second-degree relatives to document mutation in MPZ gene indicating diagnosis of Charcot-Marie-Tooth disease type 1B. There were 103 patients from 71 families with 47 different MPZ mutations with a mean age of 40 years (range 3-84 years). Patients and mutations were separated into infantile, childhood and adult-onset groups. The infantile onset group had higher Charcot-Marie-Tooth disease neuropathy score version 1 or 2 and slower nerve conductions than the other groups, and severity increased with age. Twenty-three patients had no family history of Charcot-Marie-Tooth disease. Sixty-one patients wore foot/ankle orthoses, 19 required walking assistance or support, and 10 required wheelchairs. There was hearing loss in 21 and scoliosis in 17. Forty-two patients did not begin walking until after 15 months of age. Half of the infantile onset patients then required ambulation aids or wheelchairs for

  13. Most Trial Eligibility Criteria and Patient Baseline Characteristics Do Not Modify Treatment Effect in Trials Using Targeted Therapies for Rheumatoid Arthritis

    DEFF Research Database (Denmark)

    Christensen, Anton Wulf; Tarp, Simon; Furst, Daniel E;

    2015-01-01

    rheumatoid arthritis (RA). METHODS: We conducted a meta-epidemiological study of all trials evaluating a targeted therapy approved by regulatory authorities for treating RA. The database search was completed on December 11th 2013. Eligible trials reported ACR20 data at months 3-6 and used an add-on design......OBJECTIVE: To determine if variations in trial eligibility criteria and patient baseline characteristics could be considered effect modifiers of the treatment response when testing targeted therapies (biological agents and targeted synthetic disease modifying antirheumatic drugs (DMARDs)) for...

  14. Baseline characteristics, response to and outcome of antiretroviral therapy among patients with HIV-1, HIV-2 and dual infection in Burkina Faso.

    OpenAIRE

    Harries, Katie; Zachariah, Rony; Manzi, Marcel; Firmenich, Peter; Mathela, Richard; Drabo, Joseph; Onadja, G; Arnould, Line; Harries, A. D.

    2009-01-01

    In an urban district hospital in Burkina Faso we investigated the relative proportions of HIV-1, HIV-2 and HIV-1/2 among those tested, the baseline sociodemographic and clinical characteristics, and the response to and outcome of antiretroviral therapy (ART). A total of 7368 individuals (male=32%; median age=34 years) were included in the analysis over a 6 year period (2002-2008). The proportions of HIV-1, HIV-2 and dual infection were 94%, 2.5% and 3.6%, respectively. HIV-1-infected individu...

  15. Diabetes treatment patterns and goal achievement in primary diabetes care (DiaRegis - study protocol and patient characteristics at baseline

    Directory of Open Access Journals (Sweden)

    Deeg Evelin

    2010-09-01

    Full Text Available Abstract Background Patients with type 2 diabetes are at an increased risk for disease and treatment related complications after the initial approach of oral mono/dual antidiabetic therapy has failed. Data from clinical practice with respect to this patient group are however scarce. Therefore we set up a registry in primary care documenting the course and outcomes of this patient group. Methods Diabetes Treatment Patterns and Goal Achievement in Primary Diabetes Care (DiaRegis is a prospective, observational, German, multicenter registry including patients with type-2 diabetes in which oral mono/dual antidiabetic therapy has failed. Data were recorded at baseline and will be prospectively documented during visits at 6 ± 1, 12 ± 2 and 24 ± 2 months. The primary objective is to estimate the proportion of patients with at least 1 episode of severe hypoglycemia within one year. Results 313 primary care offices included 4,048 patients between June 2009 and March 2010 of which 3,810 patients fulfilled the in- and exclusion criteria. 46.7% of patients were female; patients had a median diabetes duration of 5.5 years and most were obese with respect to BMI or waist circumference. HbA1c at baseline was 7.4%, fasting plasma glucose 142 mg/dl and postprandial glucose 185 mg/dl. Co-morbidity in this patient population was substantial with 17.9% having coronary artery disease, 14.4% peripheral neuropathy, 9.9% heart failure and 6.0% peripheral arterial disease. 68.6% of patients received oral monotherapy, 31.4% dual oral combination therapy. The most frequent antidiabetic agent used as monotherapy was metformin (79.0% followed by sulfonylureas (14.8%. Conclusions DiaRegis is a large, prospective registry in primary diabetes care to document the course and outcomes of patients with type-2 diabetes in which the initial approach of oral mono/dual antidiabetic therapy has failed. The two year follow-up will allow for a prospective evaluation of these patients

  16. Potential Effects of a Scenario Earthquake on the Economy of Southern California: Baseline County-Level Migration Characteristics and Trends 1995-2000 and 2001-2010

    Science.gov (United States)

    Sherrouse, Benson C.; Hester, David J.

    2008-01-01

    The Multi-Hazards Demonstration Project (MHDP) is a collaboration between the U.S. Geological Survey (USGS) and various partners from the public and private sectors and academia, meant to improve Southern California's resiliency to natural hazards. In support of the MHDP objectives, the ShakeOut Scenario was developed. It describes a magnitude 7.8 earthquake along the southernmost 300 kilometers (200 miles) of the San Andreas Fault, identified by geoscientists as a plausible event that will cause moderate to strong shaking over much of the eight-county (Imperial, Kern, Los Angeles, Orange, Riverside, San Bernardino, San Diego, and Ventura) Southern California region. This report uses historical, estimated, and projected population data from several Federal and State data sources to estimate baseline characteristics and trends of the region's population migration (that is, changes in a person's place of residence over time). The analysis characterizes migration by various demographic, economic, family, and household variables for the period 1995-2000. It also uses existing estimates (beginning in 2001) of the three components of population change - births, deaths, and migration - to extrapolate near-term projections of county-level migration trends through 2010. The 2010 date was chosen to provide baseline projections corresponding to a two-year recovery period following the November 2008 date that was selected for the occurrence of the ShakeOut Scenario earthquake. The baseline characteristics and projections shall assist with evaluating the effects of inflow and outflow migration trends for alternative futures in which the simulated M7.8 earthquake either does or does not occur and the impact of the event on housing and jobs, as well as community composition and regional economy changes based on dispersion of intellectual, physical, economic, and cultural capital.

  17. Nonlinear undulator tapering in conventional SASE regime at baseline electron beam parameters as a way to optimize the radiation characteristics of the European XFEL

    Energy Technology Data Exchange (ETDEWEB)

    Serkez, Svitozar; Kocharyan, Vitali; Saldin, Evgeni; Zagorodnov, Igor [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Geloni, Gianluca [European XFEL GmbH, Hamburg (Germany)

    2013-09-15

    We demonstrate that the output radiation characteristics of the European XFEL sources at nominal operation point can be easily made significantly better than what is currently reported in the TDRs of scientific instruments and X-ray optics. In fact, the output SASE characteristics of the baseline European XFEL have been previously optimized assuming uniform undulators at a nominal operating point of 5 kA peak current, without considering the potential of undulator tapering in the SASE regime. In order to illustrate this point, we analyze the case of an electron bunch with nominal parameters. Based on start-to-end simulations, we demonstrate that nonlinear undulator tapering allows one to achieve up to a tenfold increase in peak power and photon spectral density in the conventional SASE regime, without modification to the baseline design. The FEL code Genesis has been extensively used for these studies. In order to increase our confidence in simulation results, we cross-checked outcomes by reproducing simulations in the deep nonlinear SASE regime with tapered undulator using the code ALICE.

  18. Nonlinear undulator tapering in conventional SASE regime at baseline electron beam parameters as a way to optimize the radiation characteristics of the European XFEL

    CERN Document Server

    Serkez, Svitozar; Saldin, Evgeni; Zagorodnov, Igor; Geloni, Gianluca

    2013-01-01

    We demonstrate that the output radiation characteristics of the European XFEL sources at nominal operation point can be easily made significantly better than what is currently reported in the TDRs of scientific instruments and X-ray optics. In fact, the output SASE characteristics of the baseline European XFEL have been previously optimized assuming uniform undulators at a nominal operating point of 5 kA peak current, without considering the potential of udulator tapering in the SASE regime. In order to illustrate this point, we analyze the case of an electron bunch with nominal parameters. Based on start-to-end simulations, we demonstrate that nonlinear undulator tapering allows one to achieve up to a tenfold increase in peak power and photon spectral density in the conventional SASE regime, without modification to the baseline design. The FEL code Genesis has been extensively used for these studies. In order to increase our confidence in simulation results, we cross-checked outcomes by reproducing simulatio...

  19. Nonlinear undulator tapering in conventional SASE regime at baseline electron beam parameters as a way to optimize the radiation characteristics of the European XFEL

    International Nuclear Information System (INIS)

    We demonstrate that the output radiation characteristics of the European XFEL sources at nominal operation point can be easily made significantly better than what is currently reported in the TDRs of scientific instruments and X-ray optics. In fact, the output SASE characteristics of the baseline European XFEL have been previously optimized assuming uniform undulators at a nominal operating point of 5 kA peak current, without considering the potential of undulator tapering in the SASE regime. In order to illustrate this point, we analyze the case of an electron bunch with nominal parameters. Based on start-to-end simulations, we demonstrate that nonlinear undulator tapering allows one to achieve up to a tenfold increase in peak power and photon spectral density in the conventional SASE regime, without modification to the baseline design. The FEL code Genesis has been extensively used for these studies. In order to increase our confidence in simulation results, we cross-checked outcomes by reproducing simulations in the deep nonlinear SASE regime with tapered undulator using the code ALICE.

  20. [Comparative study of the effect of fasting during Ramadan on the glycaemia at rest in sportsmen and sedentaries].

    Science.gov (United States)

    Ba, A; Samb, A; Seck, D; Kane, M O; Seck, M B; Sarr, F B; Ciss, M; Gueye, L; Cisse, F

    2005-01-01

    The fast of Ramadan submits body to transient metabolic modifications; and decrease of glycaemia can be one of results. Physical exercise modifies rate of plasmatic hormones responsible for its regulation. The purpose of this study is to appreciate the influence of the fast on this biologic parameter in sportsmen and sedentaries. Thirty (30) healthy subjects (15 sportsmen of stamina and 15 sedentaries), with 25 years of average age were recruited. They have all a comparable diet. We excluded subjects having practised a physical exercise the day of the test. Capillary glycaemia was measured after weighed and physical exam, in 2 periods: in second Ramadan's fortnight, 15 minutes before food intake, two (2) months after Ramadan at least 4 hours at distance of the last meal. Comparisons were remitted in the test of Student, significant for p value lower than 0.05. During Ramadan, the glycaemia of the sportsmen at rest, is at one exception always superior or equal to that of the sedentaries. However, there is non significant difference as much during the fast as in normal food intake. Respective averages are 4.6 mmol/l, 0.15 and 4.5 mmol/l, 0.01 during Ramadan. They cross then in 4.8 mmol/l, 0.2 and 4.8 mmol/l, 0.4 in normal food intake. Landmark, the comparison of the averages from period to the other one in every group shows a significant difference only for the sedentaries. The return to normal food intake was expressed by an important gain in weight for all subjects. The fast of Ramadan has no notorious influence on sportsman's glycaemia contrary to that of sedentary. In other words, the sportsman administers better his stocks of glucose. Previous works however strongly advised against sports practice during Ramadan and more particularly the competitions, because, exercises of strong intensity can induce dehydration. PMID:16190121

  1. The influence of maternal glycaemia and dietary glycaemic index on pregnancy outcome in healthy mothers.

    LENUS (Irish Health Repository)

    McGowan, Ciara A

    2010-07-01

    Infant birth weight has increased in Ireland in recent years along with levels of childhood overweight and obesity. The present article reviews the current literature on maternal glycaemia and the role of the dietary glycaemic index (GI) and its impact on pregnancy outcomes. It is known that maternal weight and weight gain significantly influence infant birth weight. Fetal macrosomia (birth weight >4000 g) is associated with an increased risk of perinatal trauma to both mother and infant. Furthermore, macrosomic infants have greater risk of being obese in childhood, adolescence and adulthood compared to normal-sized infants. There is evidence that there is a direct relationship between maternal blood glucose levels during pregnancy and fetal growth and size at birth, even when maternal blood glucose levels are within their normal range. Thus, maintaining blood glucose concentrations within normal parameters during pregnancy may reduce the incidence of fetal macrosomia. Maternal diet, and particularly its carbohydrate (CHO) type and content, influences maternal blood glucose concentrations. However, different CHO foods produce different glycaemic responses. The GI was conceived by Jenkins in 1981 as a method for assessing the glycaemic responses of different CHO. Data from clinical studies in healthy pregnant women have documented that consuming a low-GI diet during pregnancy reduces peaks in postprandial glucose levels and normalises infant birth weight. Pregnancy is a physiological condition where the GI may be of particular relevance as glucose is the primary fuel for fetal growth.

  2. Recruitment and Baseline Characteristics of Participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER—A Randomized Controlled Lifestyle Trial

    Directory of Open Access Journals (Sweden)

    Tiia Ngandu

    2014-09-01

    Full Text Available Our aim is to describe the study recruitment and baseline characteristics of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER study population. Potential study participants (age 60–77 years, the dementia risk score ≥6 were identified from previous population-based survey cohorts and invited to the screening visit. To be eligible, cognitive performance measured at the screening visit had to be at the mean level or slightly lower than expected for age. Of those invited (n = 5496, 48% (n = 2654 attended the screening visit, and finally 1260 eligible participants were randomized to the intervention and control groups (1:1. The screening visit non-attendees were slightly older, less educated, and had more vascular risk factors and diseases present. The mean (SD age of the randomized participants was 69.4 (4.7 years, Mini-Mental State Examination 26.7 (2.0 points, systolic blood pressure 140.1 (16.2 mmHg, total serum cholesterol 5.2 (1.0 mmol/L for, and fasting glucose 6.1 (0.9 mmol/L for, with no difference between intervention and control groups. Several modifiable risk factors were present at baseline indicating an opportunity for the intervention. The FINGER study will provide important information on the effect of lifestyle intervention to prevent cognitive impairment among at risk persons.

  3. Recruitment and Baseline Characteristics of Participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)—A Randomized Controlled Lifestyle Trial †

    Science.gov (United States)

    Ngandu, Tiia; Lehtisalo, Jenni; Levälahti, Esko; Laatikainen, Tiina; Lindström, Jaana; Peltonen, Markku; Solomon, Alina; Ahtiluoto, Satu; Antikainen, Riitta; Hänninen, Tuomo; Jula, Antti; Mangialasche, Francesca; Paajanen, Teemu; Pajala, Satu; Rauramaa, Rainer; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Kivipelto, Miia

    2014-01-01

    Our aim is to describe the study recruitment and baseline characteristics of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) study population. Potential study participants (age 60–77 years, the dementia risk score ≥6) were identified from previous population-based survey cohorts and invited to the screening visit. To be eligible, cognitive performance measured at the screening visit had to be at the mean level or slightly lower than expected for age. Of those invited (n = 5496), 48% (n = 2654) attended the screening visit, and finally 1260 eligible participants were randomized to the intervention and control groups (1:1). The screening visit non-attendees were slightly older, less educated, and had more vascular risk factors and diseases present. The mean (SD) age of the randomized participants was 69.4 (4.7) years, Mini-Mental State Examination 26.7 (2.0) points, systolic blood pressure 140.1 (16.2) mmHg, total serum cholesterol 5.2 (1.0) mmol/L for, and fasting glucose 6.1 (0.9) mmol/L for, with no difference between intervention and control groups. Several modifiable risk factors were present at baseline indicating an opportunity for the intervention. The FINGER study will provide important information on the effect of lifestyle intervention to prevent cognitive impairment among at risk persons. PMID:25211775

  4. Recruitment and baseline characteristics of participants in the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER)-a randomized controlled lifestyle trial.

    Science.gov (United States)

    Ngandu, Tiia; Lehtisalo, Jenni; Levälahti, Esko; Laatikainen, Tiina; Lindström, Jaana; Peltonen, Markku; Solomon, Alina; Ahtiluoto, Satu; Antikainen, Riitta; Hänninen, Tuomo; Jula, Antti; Mangialasche, Francesca; Paajanen, Teemu; Pajala, Satu; Rauramaa, Rainer; Strandberg, Timo; Tuomilehto, Jaakko; Soininen, Hilkka; Kivipelto, Miia

    2014-09-01

    Our aim is to describe the study recruitment and baseline characteristics of the Finnish Geriatric Intervention Study to Prevent Cognitive Impairment and Disability (FINGER) study population. Potential study participants (age 60-77 years, the dementia risk score ≥ 6) were identified from previous population-based survey cohorts and invited to the screening visit. To be eligible, cognitive performance measured at the screening visit had to be at the mean level or slightly lower than expected for age. Of those invited (n = 5496), 48% (n = 2654) attended the screening visit, and finally 1260 eligible participants were randomized to the intervention and control groups (1:1). The screening visit non-attendees were slightly older, less educated, and had more vascular risk factors and diseases present. The mean (SD) age of the randomized participants was 69.4 (4.7) years, Mini-Mental State Examination 26.7 (2.0) points, systolic blood pressure 140.1 (16.2) mmHg, total serum cholesterol 5.2 (1.0) mmol/L for, and fasting glucose 6.1 (0.9) mmol/L for, with no difference between intervention and control groups. Several modifiable risk factors were present at baseline indicating an opportunity for the intervention. The FINGER study will provide important information on the effect of lifestyle intervention to prevent cognitive impairment among at risk persons. PMID:25211775

  5. Epidemiology of acute coronary syndromes in a Mediterranean country; aims, design and baseline characteristics of the Greek study of acute coronary syndromes (GREECS

    Directory of Open Access Journals (Sweden)

    Stravopodis Peter

    2005-03-01

    Full Text Available Abstract Background The present study GREECS was conducted in order to evaluate the annual incidence of acute coronary syndromes (ACS and to delineate the role of clinical, biochemical, lifestyle and behavioral characteristics on the severity of disease. In this work we present the design, methodology of the study and various baseline characteristics of people with ACS. Methods/Design A sample of 6 hospitals located in Greek urban and rural regions was selected. In these hospitals we recorded almost all admissions due to ACS, from October 2003 to September 2004. Socio-demographic, clinical, dietary, psychological and other lifestyle characteristics were recorded. 2172 patients were included in the study (76% were men and 24% women. The crude annual incidence rate was 22.6 per 10,000 people and the highest frequency of events was observed in winter. The in-hospital mortality rate was 4.3%. The most common discharged diagnosis for men was Q-wave MI, while for women it was unstable angina. Discussion This study aims to demonstrate current information about the epidemiology of patients who suffer from ACS, in Greece.

  6. LOG ON RATE AND BASELINE CHARACTERISTICS IN A WEB BASED PROGRAM PROMOTING HEALTHY EATING BEHAVIORS TO PARENTS/GUARDIANS OF 8-12 YEAR OLD AFRICAN-AMERICAN GIRLS

    Science.gov (United States)

    Background: In web-based programs, log on rate (LOR) determines program dose. Little is known about factors influencing LOR. Computer self-efficacy (CSE) and personal characteristics are likely influencers. Purpose: To examine relationships between LOR, CSE, and baseline characteristics of particip...

  7. Baseline characteristics of the IMPROVE control study population: A study to evaluate the effectiveness of a standardized healthcare professionals training program

    Directory of Open Access Journals (Sweden)

    S K Sharma

    2012-01-01

    Full Text Available Introduction: The IMPROVE Control Training program was designed by Indian Academy of Diabetes (IAD, and a non-intervention study was conducted to evaluate the effectiveness of this standardized healthcare professionals (HCPs training program on achieving treatment goals in patients with diabetes mellitus and its impact on standard of care. Materials and Methods: This multi-center, parallel group, open-label, non-randomized, non-intervention study included patients with type 2 diabetes who had an HbA1c >9 at time of diagnosis or an HbA1c >7% even after 6 months of initiation of therapy with anti-diabetic agents (Oral anti diabetic agents (OADs and/or insulin. The data recorded at baseline included demographic characteristics, medical history, and the treatment regimens. Results: The study included 20,493 patients with diabetes, of which 13,295 (64.9% were men. The mean [standard deviation (SD] duration of diabetes was 6.4 (4.2 years and 6608 (32.2% reported complications of diabetes. Poor glycemic control [HbA1c = 9.4 (1.3, FPG (mg/dl = 181.2 (45.7; mean (SD] was observed. The postprandial glucose was also high [post-breakfast, lunch, and dinner values in mg/dl were 263.6 (68.5, 278.1 (69.6, and 250.2 (63.7, respectively] in these patients. Failure of OADs was the most common reason cited for initiation of insulin. Premixed insulin was rated the regimen of choice for initiating therapy by the physicians (62.2% vs. 34.5% who preferred basal insulin. Conclusion: The baseline results confirm the poor glycemic control and the delayed initiation and/or inadequacy of treatment in subjects with type 2 diabetes. These results also highlight the need for early and optimal insulin-based therapy.

  8. Evolution of glycaemia during irradiation syndrome; Evolution de la glycemie au cours du syndrome d'irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Raisonnier, A. [Commissariat a l' Energie Atomique, Fontenay aux Roses (France). Centre d' Etudes Nucleaires

    1967-03-15

    The evolution of glycaemia following irradiation has been followed in the rat and pig. The results concerning a case of human accidental exposure have also been included. The author has tried to see whether the observed variations are reproducible and have a prognostic value. (author) [French] L'evolution de la glycemie a ete suivie, chez le rat et le porc, apres irradiation. Les resultats relatifs a une irradiation accidentelle humaine sont egalement rapportes. L'auteur cherche a definir si les variations observees sont reproductibles et ont une valeur pronostique. (auteur)

  9. [Comparative study of postprandial glycaemia in type 2 diabetic patients after consumption of mono- and disaccharides and sweeteners].

    Science.gov (United States)

    Sharafetdinov, Kh Kh; Meshcheriakova, V A; Plotnikova, O A; Gapparov, M G

    2002-01-01

    It was investigated the influence of mono- and disaccharides, sugar alcohols, honey, corn patoka and products with nutritive and nonnutritive sweeteners on dynamic of postprandial glycaemia in type 2 diabetic patients. After ingestion of 30 g fructose, blood glucose did not show a marked increase in comparison with sucrose or honey. After ingestion of 30 g sorbitol or isomalt, blood glucose curve was not significantly different. It was indicated that corn patoka in chewing candies with isomalt has a high hyperglycaemic effect whereas drink with nonnutritive sweeteners did not change blood glucose from fasting levels. PMID:12125470

  10. Implementation of case management to reduce cardiovascular disease risk in the Stanford and San Mateo Heart to Heart randomized controlled trial: study protocol and baseline characteristics

    Directory of Open Access Journals (Sweden)

    Stafford Randall S

    2006-09-01

    Full Text Available Abstract Background Case management has emerged as a promising alternative approach to supplement traditional one-on-one sessions between patients and doctors for improving the quality of care in chronic diseases such as coronary heart disease (CHD. However, data are lacking in terms of its efficacy and cost-effectiveness when implemented in ethnic and low-income populations. Methods The Stanford and San Mateo Heart to Heart (HTH project is a randomized controlled clinical trial designed to rigorously evaluate the efficacy and cost-effectiveness of a multi-risk cardiovascular case management program in low-income, primarily ethnic minority patients served by a local county health care system in California. Randomization occurred at the patient level. The primary outcome measure is the absolute CHD risk over 10 years. Secondary outcome measures include adherence to guidelines on CHD prevention practice. We documented the study design, methodology, and baseline sociodemographic, clinical and lifestyle characteristics of 419 participants. Results We achieved equal distributions of the sociodemographic, biophysical and lifestyle characteristics between the two randomization groups. HTH participants had a mean age of 56 years, 63% were Latinos/Hispanics, 65% female, 61% less educated, and 62% were not employed. Twenty percent of participants reported having a prior cardiovascular event. 10-year CHD risk averaged 18% in men and 13% in women despite a modest low-density lipoprotein cholesterol level and a high on-treatment percentage at baseline. Sixty-three percent of participants were diagnosed with diabetes and an additional 22% had metabolic syndrome. In addition, many participants had depressed high-density lipoprotein (HDL cholesterol levels and elevated values of total cholesterol-to-HDL ratio, triglycerides, triglyceride-to-HDL ratio, and blood pressure. Furthermore, nearly 70% of participants were obese, 45% had a family history of CHD or

  11. [Influence of breads with use of barley, buckwheat and oat flours and barley flakes on postprandial glycaemia in patients with type 2 diabetes mellitus].

    Science.gov (United States)

    Sharafetdinov, Kh Kh; Gapparov, M M; Plotnikova, O A; Zykina, V V; Shlelenko, L A; Tiurina, O E; Rabotkin, Iu V

    2009-01-01

    It was investigated the influence of breads with use of barley, buckwheat and oat flours and barley flakes on postprandial glycaemia in patients with type 2 diabetes mellitus. It was shown that consumption of breads with use of barley and buckwheat flours is accompanied less marked postprandial glycaemic reaction in compared with standard loading of carbohydrates (wheat bread). Also it was noted greater increase of postprandial glycaemia in consumption of bread with use of barley flakes in compared with consumption of wheat bread inclusive equivalent amount of carbohydrates. PMID:19999818

  12. The Pap smear screening as an occasion for smoking cessation and physical activity counselling: baseline characteristics of women involved in the SPRINT randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Chellini Elisabetta

    2011-12-01

    Full Text Available Abstract Background Gender-specific smoking cessation strategies have rarely been developed. Evidence of effectiveness of physical activity (PA promotion and intervention in adjunct to smoking cessation programs is not strong. SPRINT study is a randomized controlled trial (RCT designed to evaluate a counselling intervention on smoking cessation and PA delivered to women attending the Italian National Health System Cervical Cancer Screening Program. This paper presents study design and baseline characteristics of the study population. Methods/Design Among women undergoing the Pap examination in three study centres (Florence, Turin, Mantua, participants were randomized to the smoking cessation counselling [S], the smoking cessation + PA counselling [S + PA], or the control [C] groups. The program under evaluation is a standard brief counselling on smoking cessation combined with a brief counselling on increasing PA, and was delivered in 2010. A questionnaire, administered before, after 6 months and 1 year from the intervention, was used to track behavioural changes in tobacco use and PA, and to record cessation rates in participants. Discussion Out of the 5,657 women undergoing the Pap examination, 1,100 participants (55% of smokers were randomized in 1 of the 3 study groups (363 in the S, 366 in the S + PA and 371 in the C groups. The three arms did not differ on any demographic, PA, or tobacco-use characteristics. Recruited smokers were older, less educated than non-participant women, more motivated to quit (33% vs.9% in the Preparation stage, p p p Trial registration number ISRCTN: ISRCTN52660565

  13. Profile of cortisol, glycaemia, and blood parameters of American Bullfrog tadpoles Lithobates catesbeianus exposed to density and hypoxia stressors

    Directory of Open Access Journals (Sweden)

    Patricia C. Teixeira

    2012-12-01

    Full Text Available The aim of this study was to evaluate alterations to the physiological profile (cortisol, glycaemia, and blood parameters of Lithobates catesbeianus caused by the stressors density and hypoxia. The organisms were in the prometamorphosis stage and exposed to different tadpole densities: 1 tadpole/L (T1, 5 tadpoles/L (T2, and 10 tadpoles/L (T3 for 12 days. The blood was collected through the rupture of the caudal blood vessel and collected under normoxia (immediate collection and hypoxia (after 15 minutes of air exposure conditions. Cortisol levels rose on the fourth and eighth days of treatment and returned to basal levels by the end of the experiment. The stressor mechanisms tested did not affect glycaemia. White blood cells (total number of lymphocytes, neutrophils, and eosinophils showed a significant difference at the twelfth day of the experiment when compared with the start of the experiment. We concluded that, under controlled conditions, a density of up to 10 tadpoles/L and air exposure for 15 minutes did not cause harmful physiological alterations during the experimental period. The answer to these stressors maybe was in another hormonal level (corticosterone.

  14. Incomplete reporting of baseline characteristics in clinical trials: an analysis of randomized controlled trials and systematic reviews involving patients with chronic low back pain.

    Directory of Open Access Journals (Sweden)

    Maria M Wertli

    Full Text Available OBJECTIVE: The aim of this study was to evaluate the reporting of relevant prognostic information in a sample of randomized controlled trials (RCTs that investigated treatments for patients with chronic low back pain (LBP. We also analysed how researchers conducting the meta-analyses and systematic reviews addressed the reporting of relevant prognostic information in RCTs. METHODS: We searched the Cochrane Database to identify systematic reviews that investigated non-surgical treatments for patients with chronic LBP. The reported prognostic information was then extracted from the RCTs included in the reviews. We used a purpose-defined score to assess the quantity of information reported in the RCTs. We also determined how the authors of systematic reviews addressed the question of comparability of patient populations between RCTs. RESULTS: Six systematic reviews met our inclusion criteria, and we analysed 84 RCTs. Based on the scores, the reporting of important prognostic variables was incomplete in almost half of the 84 RCTs. Information regarding patients' general health, social support, and work-related conditions was rarely reported. Almost half of the studies included in one of the meta-analyses provided insufficient information that did not allow us to determine whether patients in the primary trials were comparable. CONCLUSIONS: Missing prognostic information potentially threatens the external validity (i.e. the generalizability or applicability not only of primary studies but also of systematic reviews that investigate treatments for LBP. A detailed description of baseline patient characteristics that includes prognostic information is needed in all RCTs to ensure that clinicians can determine the applicability of the study or review results to their patients.

  15. Neuroendocrine disruption in the shore crab Carcinus maenas: Effects of serotonin and fluoxetine on chh- and mih-gene expression, glycaemia and ecdysteroid levels.

    Science.gov (United States)

    Robert, Alexandrine; Monsinjon, Tiphaine; Delbecque, Jean-Paul; Olivier, Stéphanie; Poret, Agnès; Foll, Frank Le; Durand, Fabrice; Knigge, Thomas

    2016-06-01

    Serotonin, a highly conserved neurotransmitter, controls many biological functions in vertebrates, but also in invertebrates. Selective serotonin reuptake inhibitors (SSRIs), such as fluoxetine, are commonly used in human medication to ease depression by affecting serotonin levels. Their residues and metabolites can be detected in the aquatic environment and its biota. They may also alter serotonin levels in aquatic invertebrates, thereby perturbing physiological functions. To investigate whether such perturbations can indeed be expected, shore crabs (Carcinus maenas) were injected either with serotonin, fluoxetine or a combination of both. Dose-dependent effects of fluoxetine ranging from 250 to 750nM were investigated. Gene expression of crustacean hyperglycemic hormone (chh) as well as moult inhibiting hormone (mih) was assessed by RT-qPCR at 2h and 12h after injection. Glucose and ecdysteroid levels in the haemolymph were monitored in regular intervals until 12h. Serotonin led to a rapid increase of chh and mih expression. On the contrary, fluoxetine only affected chh and mih expression after several hours, but kept expression levels significantly elevated. Correspondingly, serotonin rapidly increased glycaemia, which returned to normal or below normal levels after 12h. Fluoxetine, however, resulted in a persistent low-level increase of glycaemia, notably during the period when negative feedback regulation reduced glycaemia in the serotonin treated animals. Ecdysteroid levels were significantly decreased by serotonin and fluoxetine, with the latter showing less pronounced and less rapid, but longer lasting effects. Impacts of fluoxetine on glycaemia and ecdysteroids were mostly observed at higher doses (500 and 750nM) and affected principally the response dynamics, but not the amplitude of glycaemia and ecdysteroid-levels. These results suggest that psychoactive drugs are able to disrupt neuroendocrine control in decapod crustaceans, as they interfere with the

  16. Bipolar II compared with bipolar I disorder: baseline characteristics and treatment response to quetiapine in a pooled analysis of five placebo-controlled clinical trials of acute bipolar depression

    OpenAIRE

    Datto, Catherine; Pottorf, William J.; Feeley, Louisa; LaPorte, Scott; Liss, Charlie

    2016-01-01

    Background Bipolar I and II represent the most common and severe subtypes of bipolar disorder. Although bipolar I disorder is relatively well studied, the clinical characteristics and response to treatment of patients with bipolar II disorder are less well understood. Methods To compare the severity and burden of illness of patients with bipolar II versus bipolar I disorder, baseline demographic, clinical, and quality of life data were examined in 1900 patients with bipolar I and 973 patients...

  17. Double blind randomized placebo-controlled trial on the effects of testosterone supplementation in elderly men with moderate to low testosterone levels: design and baseline characteristics [ISRCTN23688581

    Directory of Open Access Journals (Sweden)

    Verhaar Harald JJ

    2006-08-01

    Full Text Available Abstract In ageing men testosterone levels decline, while cognitive function, muscle and bone mass, sexual hair growth, libido and sexual activity decline and the risk of cardiovascular diseases increase. We set up a double-blind, randomized placebo-controlled trial to investigate the effects of testosterone supplementation on functional mobility, quality of life, body composition, cognitive function, vascular function and risk factors, and bone mineral density in older hypogonadal men. We recruited 237 men with serum testosterone levels below 13.7 nmol/L and ages 60–80 years. They were randomized to either four capsules of 40 mg testosterone undecanoate (TU or placebo daily for 26 weeks. Primary endpoints are functional mobility and quality of life. Secondary endpoints are body composition, cognitive function, aortic stiffness and cardiovascular risk factors and bone mineral density. Effects on prostate, liver and hematological parameters will be studied with respect to safety. Measure of effect will be the difference in change from baseline visit to final visit between TU and placebo. We will study whether the effect of TU differs across subgroups of baseline waist girth ( At baseline, mean age, BMI and testosterone levels were 67 years, 27 kg/m2 and 10.72 nmol/L, respectively.

  18. On the possibility to affect the course of glycaemia, insulinaemia, and perceived hunger/satiety to bread meals in healthy volunteers.

    Science.gov (United States)

    Ekström, Linda M N K; Björck, Inger M E; Ostman, Elin M

    2013-04-25

    Frequent hyperglycaemia is associated with oxidative stress and subclinical inflammation, and thus increased risk of cardiovascular disease. Possibilities of modulating glycaemia, insulinaemia and perceived satiety for bread products were investigated, with emphasis on the course of glycaemia expressed as a glycaemic profile (defined as the duration of the glucose curve above the fasting concentration divided by the incremental glucose peak). For this purpose white wheat bread was supplemented with whole grain corn flour with an elevated amylose content and different types and levels of guar gum. The bread products were characterised in vitro for release of starch degradation products and content of resistant starch. Fibre related fluidity following enzyme hydrolysis was also studied. By combining medium weight guar gum and whole grain corn flour with an elevated amylose content, the course of glycaemia, insulinaemia and subjective appetite ratings were improved compared to the reference white wheat bread. In addition, the combination beneficially influenced the content of resistant starch. Fluidity measurements showed potential to predict the glycaemic profile. PMID:23334658

  19. Polychlorinated biphenyls, glycaemia and diabetes in a population living in a highly polychlorinated biphenyls-polluted area in northern Italy: a cross-sectional and cohort study

    Directory of Open Access Journals (Sweden)

    Claudia Zani

    2013-05-01

    Full Text Available Background. Polychlorinated biphenyls (PCBs have been found to be associated with diabetes in some, but not all, studies performed so far. The aim of this study was to assess the association between PCB serum levels and glycaemia and diabetes in people living in Brescia, a highly industrialised PCB-polluted town in Northern Italy. Design and Methods. 527 subjects were enrolled in a cross-sectional population-based study: they were interviewed face-to-face in 2003 and also provided a blood sample under fasting conditions. The concentration of 24 PCB congeners was determined using gas-chromatography (GC/MS. Subsequently, all subjects were included in a follow-up (cohort study. According to the Local Health Authority health-care database, subjects were considered to be diabetic if they had diabetes at interview time (prevalent cases or during a 7-year follow-up (incident cases. Results. A total of 53 subjects (10.0% were diabetics: 28 had dia- betes at enrolment and other 25 developed the disease subsequently. Diabetes frequency increased according to the serum concentrations of total PCBs and single PCB congeners, but no association was found when estimates were adjusted for education, body mass index, age and gender by logistic regression analysis. Accordingly, glycaemia increased with PCB serum levels, but no association was observed when multiple regression analysis, including confounding factors, was performed. Conclusions. This study does not support the hypothesis that PCB environmental exposure is strictly associated with diabetes or glycaemia.

  20. Patient-orientated longitudinal study of multiple sclerosis in south west England (The South West Impact of Multiple Sclerosis Project, SWIMS 1: protocol and baseline characteristics of cohort

    Directory of Open Access Journals (Sweden)

    Wright Dave E

    2010-10-01

    Full Text Available Abstract Background There is a need for greater understanding of the impact of multiple sclerosis (MS from the perspective of individuals with the condition. The South West Impact of MS Project (SWIMS has been designed to improve understanding of disease impact using a patient-centred approach. The purpose is to (1 develop improved measurement instruments for clinical trials, (2 evaluate longitudinal performance of a variety of patient-reported outcome measures, (3 develop prognostic predictors for use in individualising drug treatment for patients, particularly early on in the disease course. Methods This is a patient-centred, prospective, longitudinal study of multiple sclerosis and clinically isolated syndrome (CIS in south west England. The study area comprises two counties with a population of approximately 1.7 million and an estimated 1,800 cases of MS. Self-completion questionnaires are administered to participants every six months (for people with MS or 12 months (CIS. Here we present descriptive statistics of the baseline data provided by 967 participants with MS. Results Seventy-five percent of those approached consented to participate. The male:female ratio was 1.00:3.01 (n = 967. Average (standard deviation age at time of entry to SWIMS was 51.6 (11.5 years (n = 961 and median (interquartile range time since first symptom was 13.3 (6.8 to 24.5 years (n = 934. Fatigue was the most commonly reported symptom, with 80% of participants experiencing fatigue at baseline. Although medication use for symptom control was common, there was little evidence of effectiveness, particularly for fatigue. Nineteen percent of participants were unable to classify their subtype of MS. When patient-reported subtype was compared to neurologist assessment for a sample of participants (n = 396, agreement in disease sub-type was achieved in 63% of cases. There were 836 relapses, reported by 931 participants, in the twelve months prior to baseline. Twenty

  1. Randomized intervention trial on preventive home visits to older people: baseline and follow-up characteristics of participants and non-participants

    DEFF Research Database (Denmark)

    Vass, Mikkel; Avlund, Kirsten; Hendriksen, Carsten

    2007-01-01

    AIMS: In controlled intervention studies, a selective non-response or refusal to participate at baseline may bias measurable effects of the intervention. The aim of this study was to compare mortality and nursing home admission among older persons who accepted (participants) and older person who...... a significantly higher mortality rate and risk of admission to nursing home than participants, whereas the subgroups of non-participants describing themselves as "too healthy" and having "another reason for refusal" did not differ from the participants. There was no difference in mortality rates...

  2. Association of Admission Glycaemia With High Grade Atrioventricular Block in ST-Segment Elevation Myocardial Infarction Undergoing Reperfusion Therapy: An Observational Study.

    Science.gov (United States)

    Huang, Bi; Wang, Xinjie; Yang, Yanmin; Zhu, Jun; Liang, Yan; Tan, Huiqiong; Yu, Litian; Gao, Xin; Zhang, Han; Wang, Juan

    2015-07-01

    Several studies have demonstrated the association between elevated admission glycaemia (AG) and the occurrence of some arrhythmias such as atrial fibrillation, ventricular tachycardia, and ventricular fibrillation after myocardial infarction. However, the impact of elevated AG on the high grade atrioventricular block (AVB) occurrence after ST-segment elevation myocardial infarction (STEMI) remains unclear. Included were 3359 consecutive patients with STEMI who received reperfusion therapy. The primary endpoint was the development of high grade AVB during hospital course. Patients were divided into non-diabetes mellitus (DM), newly diagnosed DM, and previously known DM according to the hemoglobin A1c level. The optimal AG value was determined by receiver operating characteristic curves analysis with AG predicting the high grade AVB occurrence. The best cut-off value of AG for predicting the high grade AVB occurrence was 10.05 mmol/L by ROC curve analysis. The prevalence of AG ≥ 10.05 mmol/L in non-DM, newly diagnosed DM, and previously known DM was 15.7%, 34.1%, and 68.5%, respectively. The incidence of high grade AVB was significantly higher in patients with AG ≥ 10.05  mmol/L than risk of high grade AVB occurrence in non-DM (HR = 1.826, 95% CI 1.073-3.107, P = 0.027) and in newly diagnosed DM (HR = 5.252, 95% CI 1.890-14.597, P = 0.001). Moreover, both AG ≥ 10.05  mmol/L and high grade AVB were independent risk factors of 30-day all cause-mortality (HR = 1.362, 95% CI 1.006-1.844, P = 0.046 and HR = 2.122, 95% CI 1.154-3.903, P = 0.015, respectively). Our study suggested that elevated AG level (≥10.05  mmol/L) might be an indicator of increased risk of high grade AVB occurrence in patients with STEMI. PMID:26181562

  3. Urinary Obstruction in Prostate Cancer Patients From the Dutch Trial (68 Gy vs. 78 Gy): Relationships With Local Dose, Acute Effects, and Baseline Characteristics

    International Nuclear Information System (INIS)

    Purpose: To investigate the relationship between late urinary obstruction and the details of the dose distribution of irradiated prostate cancer patients, taking into account their baseline symptoms and acute complaints. Patients and Methods: We selected patients from the Dutch multicenter trial randomized between 68 Gy and 78 Gy, for whom toxicity data and dose data were available (n = 557). The absolute dose surface parameters of the delineated bladder were calculated. Next, we constructed three-dimensional dose maps of the area around the prostate, providing an approximate identification of the corresponding anatomic locations. The dose difference maps were constructed by subtracting the mean dose maps of the patients with and without late urinary obstruction. Selected local dose points were analyzed using Cox regression analysis. Results: Urinary obstruction was scored for 40 patients, including 19 of 296 patients who received 68-72 Gy and 21 of 261 patients who received 76-78 Gy. A total of 19 events occurred within 2 years after irradiation and 21 events after 2 years. The bladder surface receiving ≥80 Gy predicted (p <.01) the occurrence of obstruction within 2 years. The dose difference map indicated highly significant differences in the bladder neck situated in the trigonal region (p < .001) that were especially predictive of obstruction after 2 years and of the diagnosis of bladder neck obstruction. Baseline complaints and transurethral resection of the prostate and acute complaints were mainly predictive for obstruction within 2 years. Conclusion: Relatively early events of urinary obstruction were associated with urinary problems existing before RT, acute toxicity, previous transurethral resection of the prostate, and hotspots in the bladder. Events after 2 years were associated with the local dose in the trigonal area.

  4. Demography, baseline disease characteristics and treatment history of patients with psoriasis enrolled in a multicentre, prospective, disease-based registry (PSOLAR)*

    OpenAIRE

    Kimball, AB; Leonardi, C; Stahle, M.; Gulliver, W; Chevrier, M; Fakharzadeh, S; Goyal, K.; Calabro, S; Langholff, W; Menter, A

    2014-01-01

    Summary Background: Psoriasis is associated with several comorbidities and behavioural risk factors. Objectives: To evaluate demographic and disease characteristics in patients enrolled in the Psoriasis Longitudinal Assessment and Registry (PSOLAR). Methods: PSOLAR is a global, prospective, longitudinal, disease-based registry that includes a postmarketing commitment to evaluate safety in patients with psoriasis. Enrolled patients had to be receiving, or be eligible to receive, conventional s...

  5. Differences by sex in the prevalence of diabetes mellitus, impaired fasting glycaemia and impaired glucose tolerance in sub-Saharan Africa: a systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Esayas Haregot Hilawe

    2013-09-01

    Full Text Available Objective To assess differences between men and women in the prevalence of diabetes mellitus, impaired fasting glycaemia and impaired glucose tolerance in sub-Saharan Africa. Methods In September 2011, the PubMed and Web of Science databases were searched for community-based, cross-sectional studies providing sex-specific prevalences of any of the three study conditions among adults living in parts of sub-Saharan Africa (i.e. in Eastern, Middle and Southern Africa according to the United Nations subregional classification for African countries. A random-effects model was then used to calculate and compare the odds of men and women having each condition. Findings In a meta-analysis of the 36 relevant, cross-sectional data sets that were identified, impaired fasting glycaemia was found to be more common in men than in women (OR: 1.56; 95% confidence interval, CI: 1.20–2.03, whereas impaired glucose tolerance was found to be less common in men than in women (OR: 0.84; 95% CI: 0.72–0.98. The prevalence of diabetes mellitus – which was generally similar in both sexes (OR: 1.01; 95% CI: 0.91–1.11 – was higher among the women in Southern Africa than among the men from the same subregion and lower among the women from Eastern and Middle Africa and from low-income countries of sub-Saharan Africa than among the corresponding men. Conclusion Compared with women in the same subregions, men in Eastern, Middle and Southern Africa were found to have a similar overall prevalence of diabetes mellitus but were more likely to have impaired fasting glycaemia and less likely to have impaired glucose tolerance.

  6. Baseline characteristics of climate, permafrost and land cover from a new permafrost observatory in the Lena River Delta, Siberia (1998–2011

    Directory of Open Access Journals (Sweden)

    J. Boike

    2013-03-01

    Full Text Available Samoylov Island is centrally located within the Lena River Delta at 72° N, 126° E and lies within the Siberian zone of continuous permafrost. The landscape on Samoylov Island consists mainly of late Holocene river terraces with polygonal tundra, ponds and lakes, and an active floodplain. The island has been the focus of numerous multidisciplinary studies since 1993, which have focused on climate, land cover, ecology, hydrology, permafrost and limnology. This paper aims to provide a framework for future studies by describing the characteristics of the island's meteorological parameters (temperature, radiation and snow cover, soil temperature, and soil moisture. The land surface characteristics have been described using high resolution aerial images in combination with data from ground-based observations. Of note is that deeper permafrost temperatures have increased between 0.3 to 1.3 °C over the last five years. However, no clear warming of air and active layer temperatures is detected since 1998, though winter air temperatures during recent years have not been as cold as in earlier years. Data related to this article are archived under: http://doi. pangaea.de/10.1594/PANGAEA.806233 .

  7. Consumption of the Soluble Dietary Fibre Complex PolyGlycopleX® Reduces Glycaemia and Increases Satiety of a Standard Meal Postprandially

    OpenAIRE

    Solah, Vicky A.; Babette O’Mara-Wallace; Xingqiong Meng; Gahler, Roland J.; Deborah A. Kerr; James, Anthony P; Fenton, Haelee K.; Stuart K. Johnson; Simon Wood

    2016-01-01

    The effect of consumption of PolyGlycopleX® (PGX®) was compared to wheat dextrin (WD) in combination with a standard meal, on postprandial satiety and glycaemia in a double-blind, randomised crossover trial, of 14 healthy subjects trained as a satiety panel. At each of six two-hour satiety sessions, subjects consumed one of three different test meals on two separate occasions. The test meals were: a standard meal plus 5 g PGX; a standard meal plus 4.5 g of PGX as softgels; and a standard meal...

  8. Effectiveness, safety and costs of thromboembolic prevention in patients with non-valvular atrial fibrillation: phase I ESC-FA protocol study and baseline characteristics of a cohort from a primary care electronic database

    Science.gov (United States)

    Vedia Urgell, Cristina; Roso-Llorach, Albert; Morros, Rosa; Capellà, Dolors; Castells, Xavier; Ferreira-González, Ignacio; Troncoso Mariño, Amelia; Diògene, Eduard; Elorza, Josep Mª; Casajuana, Marc; Bolíbar, Bonaventura; Violan, Concepció

    2016-01-01

    Purpose Atrial fibrillation is the most common arrhythmia. Its management aims to reduce symptoms and to prevent complications through rate and rhythm control, management of concomitant cardiac diseases and prevention of related complications, mainly stroke. The main objective of Effectiveness, Safety and Costs in Atrial Fibrillation (ESC-FA) study is to analyse the drugs used for the management of the disease in real-use conditions, particularly the antithrombotic agents for stroke prevention. The aim of this work is to present the study protocol of phase I of the ESC-FA study and the baseline characteristics of newly diagnosed patients with atrial fibrillation in Catalonia, Spain. Participants The data source is System for the Improvement of Research in Primary Care (SIDIAP) database. The population included are all patients with non-valvular atrial fibrillation diagnosis registered in the electronic health records during 2007–2012. Findings to date A total of 22 585 patients with non-valvular atrial fibrillation were included in the baseline description. Their mean age was 72.8 years and 51.6% were men. The most commonly prescribed antithrombotics were vitamin K antagonists (40.1% of patients) and platelet aggregation inhibitors (32.9%); 25.3% had not been prescribed antithrombotic treatment. Age, gender, comorbidities and co-medication at baseline were similar to those reported for previous studies. Future plans The next phase in the ESC-FA study will involve assessing the effectiveness and safety of antithrombotic treatments, analysing stroke events and bleeding episodes’ rates in our patients (rest of phase I), describing the current management of the disease and its costs in our setting, and assessing how the introduction of new oral anticoagulants changes the stroke prevention in non-valvular atrial fibrillation. PMID:26823179

  9. Internalisation and multiple phosphorylation of γ-Conglutin, the lupin seed glycaemia-lowering protein, in HepG2 cells

    International Nuclear Information System (INIS)

    Highlights: •A glycaemia-reducing lupin seed protein is internalized by HepG2 cells. •The protein accumulates in the cytosol in an intact form. •The internalized protein is multiply phosphorylated. -- Abstract: Lupin seed γ-Conglutin is a protein capable of reducing glycaemia in mammalians and increasing glucose uptake by model cells. This work investigated whether γ-Conglutin is internalised into the target cells and undergoes any covalent change during the process, as a first step to understanding its mechanism of action. To this purpose, γ-Conglutin-treated and untreated HepG2 cells were submitted to confocal and transmission electron microscopy. Immune-revelation of γ-Conglutin at various intervals revealed its accumulation inside the cytosol. In parallel, 2D-electrophoresis of the cell lysates and antibody reaction of the blotted maps showed the presence of the protein intact subunits inside the treated cells, whilest no trace of the protein was found in the control cells. However, γ-Conglutin-related spots with an unexpectedly low pI were also observed in the maps. These spots were excised, trypsin-treated and submitted to MS/MS spectrometric analysis. The presence of phosphorylated amino acids was detected. These findings, by showing that γ-Conglutin is internalised by HepG2 cells in an intact form and is modified by multiple phosphorylation, open the way to the understanding of the lupin γ-Conglutin insulin-mimetic activity

  10. Internalisation and multiple phosphorylation of γ-Conglutin, the lupin seed glycaemia-lowering protein, in HepG2 cells

    Energy Technology Data Exchange (ETDEWEB)

    Capraro, Jessica [Department of Food, Environmental and Nutritional Sciences (DeFENS), Section of Chemistry and Biomolecular Sciences, Università degli Studi di Milano (UNIMI) (Italy); Magni, Chiara, E-mail: chiara.magni@unimi.it [Department of Food, Environmental and Nutritional Sciences (DeFENS), Section of Chemistry and Biomolecular Sciences, Università degli Studi di Milano (UNIMI) (Italy); Faoro, Franco; Maffi, Dario [Department of Agricultural and Environmental Sciences, UNIMI (Italy); Scarafoni, Alessio [Department of Food, Environmental and Nutritional Sciences (DeFENS), Section of Chemistry and Biomolecular Sciences, Università degli Studi di Milano (UNIMI) (Italy); Tedeschi, Gabriella; Maffioli, Elisa [Department of Veterinary Science and Public Health, UNIMI (Italy); Parolari, Anna; Manzoni, Cristina; Lovati, Maria Rosa [Department of Pharmacological and Biomolecular Sciences, UNIMI (Italy); Duranti, Marcello [Department of Food, Environmental and Nutritional Sciences (DeFENS), Section of Chemistry and Biomolecular Sciences, Università degli Studi di Milano (UNIMI) (Italy)

    2013-08-09

    Highlights: •A glycaemia-reducing lupin seed protein is internalized by HepG2 cells. •The protein accumulates in the cytosol in an intact form. •The internalized protein is multiply phosphorylated. -- Abstract: Lupin seed γ-Conglutin is a protein capable of reducing glycaemia in mammalians and increasing glucose uptake by model cells. This work investigated whether γ-Conglutin is internalised into the target cells and undergoes any covalent change during the process, as a first step to understanding its mechanism of action. To this purpose, γ-Conglutin-treated and untreated HepG2 cells were submitted to confocal and transmission electron microscopy. Immune-revelation of γ-Conglutin at various intervals revealed its accumulation inside the cytosol. In parallel, 2D-electrophoresis of the cell lysates and antibody reaction of the blotted maps showed the presence of the protein intact subunits inside the treated cells, whilest no trace of the protein was found in the control cells. However, γ-Conglutin-related spots with an unexpectedly low pI were also observed in the maps. These spots were excised, trypsin-treated and submitted to MS/MS spectrometric analysis. The presence of phosphorylated amino acids was detected. These findings, by showing that γ-Conglutin is internalised by HepG2 cells in an intact form and is modified by multiple phosphorylation, open the way to the understanding of the lupin γ-Conglutin insulin-mimetic activity.

  11. Optimizing management of glycaemia.

    Science.gov (United States)

    Chatterjee, Sudesna; Khunti, Kamlesh; Davies, Melanie J

    2016-06-01

    The global epidemic of type 2 diabetes (T2DM) continues largely unabated due to an increasingly sedentary lifestyle and obesogenic environment. A cost-effective patient-centred approach, incorporating glucose-lowering therapy and modification of cardiovascular risk factors, could help prevent the inevitable development and progression of macrovascular and microvascular complications. Glycaemic optimization requires patient structured education, self-management and empowerment, and psychological support along with early and proactive use of glucose lowering therapies, which should be delivered in a system of care as shown by the Chronic Care Model. From diagnosis, intensive glycaemic control and individualised care is aimed at reducing complications. In older people, the goal is maintaining quality of life and minimizing morbidity, especially as overtreatment increases hypoglycaemia risk. Maintaining durable glycaemic control is challenging and complex to achieve without hypoglycaemia, weight gain and other significant adverse effects. Overcoming patient and physician barriers can help ensure adequate treatment initiation and intensification. Cardiovascular safety studies with newer glucose-lowering agents are now mandatory, with a sodium glucose co-transporter-2 inhibitor (empagliflozin), and two glucagon like peptide-1 receptor agonists (liraglutide and semaglutide) being the first to demonstrate superior CV outcomes compared with placebo. PMID:27432074

  12. Kericho CLinic-based ART Diagnostic Evaluation (CLADE: design, accrual, and baseline characteristics of a randomized controlled trial conducted in predominately rural, district-level, HIV clinics of Kenya.

    Directory of Open Access Journals (Sweden)

    Fredrick K Sawe

    Full Text Available Prospective clinical trial data regarding routine HIV-1 viral load (VL monitoring of antiretroviral therapy (ART in non-research clinics of Sub-Saharan Africa are needed for policy makers.CLinic-based ART Diagnostic Evaluation (CLADE is a randomized, controlled trial (RCT evaluating feasibility, superiority, and cost-effectiveness of routine VL vs. standard of care (clinical and immunological monitoring in adults initiating dual nucleoside reverse transcriptase inhibitor (NRTI+non-NRTI ART. Participants were randomized (1:1 at 7 predominately rural, non-research, district-level clinics of western Kenya. Descriptive statistics present accrual patterns and baseline cohort characteristics.Over 15 months, 820 adults enrolled at 7 sites with 86-152 enrolled per site. Monthly site enrollment ranged from 2-92 participants. Full (100% informed consent compliance was independently documented. Half (49.9% had HIV diagnosed through voluntary counseling and testing. Study arms were similar: mostly females (57.6% aged 37.6 (SD = 9.0 years with low CD4 (166 [SD = 106] cells/m3. Notable proportions had WHO Stage III or IV disease (28.7%, BMI <18.5 kg/m2 (23.1%, and a history of tuberculosis (5.6% or were receiving tuberculosis treatment (8.2% at ART initiation. In the routine VL arm, 407/409 (99.5% received baseline VL (234,577 SD = 151,055 copies/ml. All participants received lamivudine; 49.8% started zidovudine followed by 38.4% stavudine and 11.8% tenofovir; and, 64.4% received nevirapine as nNRTI (35.6% efavirenz.A RCT can be enrolled successfully in rural, non-research, resource limited, district-level clinics in western Kenya. Many adults presenting for ART have advanced HIV/AIDS, emphasizing the importance of universal HIV testing and linkage-to-care campaigns.ClinicalTrials.gov NCT01791556.

  13. An improved course of glycaemia after a bread based breakfast is associated with beneficial effects on acute and semi-acute markers of appetite.

    Science.gov (United States)

    Ekström, Linda M N K; Björck, Inger M E; Östman, Elin M

    2016-02-17

    The prevalence of type 2 diabetes mellitus is rapidly increasing all over the world and a diet promoting reduced glycaemic excursions in the postprandial phase may help to prevent the disease. In the present study guar gum (GG) and whole grain rye flour or high amylose maize starch (HAM) was combined to design bread products giving low and sustained glycaemia. A meal study was performed with young, healthy subjects and in addition to glucose and insulin, also subjective appetite ratings and biomarkers of appetite, voluntary energy intake at a second meal and markers of fermentation were studied. The combination of GG and rye was superior with improvements in subjective appetite whereas both test products lead to improvements in biomarkers of appetite compared to the white wheat bread reference. The inclusion of GG, rye and/or HAM in bread products show great potential in lowering risk factors associated with insulin resistance and improving acute and semi-acute appetite. PMID:26762720

  14. Design and baseline characteristics of participants in the TRial of Economic Incentives to Promote Physical Activity (TRIPPA): a randomized controlled trial of a six month pedometer program with financial incentives.

    Science.gov (United States)

    Finkelstein, Eric A; Sahasranaman, Aarti; John, Geraldine; Haaland, Benjamin A; Bilger, Marcel; Sloan, Robert A; Nang, Ei Ei Khaing; Evenson, Kelly R

    2015-03-01

    Non-communicable diseases (NCDs) are emerging as the predominant global health challenge of this century. Physical inactivity is one of the primary risk factors for NCDs. Therefore, increasing physical activity levels is a public health imperative. The arrival of affordable wearable technologies, such as wireless pedometers, provides one strategy for encouraging walking. However, the effectiveness of these technologies in promoting sustained behavior change has not been established. Insights from economics suggest that incentives may be a useful strategy for increasing maintenance and effectiveness of behavior change interventions, including physical activity interventions that rely on wearable technologies. The aim of this trial is to test the effectiveness of a common wireless pedometer with or without one of two types of incentives (cash or donations to charity) for reaching weekly physical activity goals. We present here the design and baseline characteristics of participants of this four arm randomized controlled trial. 800 full-time employees (desk-bound office workers) belonging to 15 different worksites (on average, 53 (sd: 37) employees at each worksite) were successfully randomized to one of four study arms. If shown to be effective, wearable technologies in concert with financial incentives may provide a scalable and affordable health promotion strategy for governments and employers seeking to increase the physical activity levels of their constituents. PMID:25666856

  15. Baseline assessment of physical characteristics, aquatic biota, and selected water-quality properties at the reach and mesohabitat scale for three stream reaches in the Big Cypress Basin, northeastern Texas, 2010-11

    Science.gov (United States)

    Braun, Christopher L.; Moring, James B.

    2013-01-01

    The U.S. Geological Survey (USGS), in cooperation with the Northeast Texas Municipal Water District and the Texas Commission on Environmental Quality, did a baseline assessment in 2010-11 of physical characteristics and selected aquatic biota (fish and mussels) collected at the mesohabitat scale for three stream reaches in the Big Cypress Basin in northeastern Texas for which environmental flows have been prescribed. Mesohabitats are visually distinct units of habitat within the stream with unique depth, velocity, slope, substrate, and cover. Mesohabitats in reaches of Big Cypress, Black Cypress, and Little Cypress Bayous were evaluated to gain an understanding of how fish communities and mussel populations varied by habitat. Selected water-quality properties were also measured in isolated pools in Black Cypress and Little Cypress. All of the data were collected in the context of the prescribed environmental flows. The information acquired during the study will support the long-term monitoring of biota in relation to the prescribed environmental flows.

  16. Rationing with baselines

    DEFF Research Database (Denmark)

    Hougaard, Jens Leth; Moreno-Ternero, Juan D.; Østerdal, Lars Peter Raahave

    2013-01-01

    We introduce a new operator for general rationing problems in which, besides conflicting claims, individual baselines play an important role in the rationing process. The operator builds onto ideas of composition, which are not only frequent in rationing, but also in related problems such as...... bargaining, choice, and queuing. We characterize the operator and show how it preserves some standard axioms in the literature on rationing. We also relate it to recent contributions in such literature....

  17. The TDAQ Baseline Architecture

    CERN Multimedia

    Wickens, F J

    The Trigger-DAQ community is currently busy preparing material for the DAQ, HLT and DCS TDR. Over the last few weeks a very important step has been a series of meetings to complete agreement on the baseline architecture. An overview of the architecture indicating some of the main parameters is shown in figure 1. As reported at the ATLAS Plenary during the February ATLAS week, the main area where the baseline had not yet been agreed was around the Read-Out System (ROS) and details in the DataFlow. The agreed architecture has: Read-Out Links (ROLs) from the RODs using S-Link; Read-Out Buffers (ROB) sited near the RODs, mounted in a chassis - today assumed to be a PC, using PCI bus at least for configuration, control and monitoring. The baseline assumes data aggregation, in the ROB and/or at the output (which could either be over a bus or in the network). Optimization of the data aggregation will be made in the coming months, but the current model has each ROB card receiving input from 4 ROLs, and 3 such c...

  18. FED baseline engineering studies report

    Energy Technology Data Exchange (ETDEWEB)

    Sager, P.H.

    1983-04-01

    Studies were carried out on the FED Baseline to improve design definition, establish feasibility, and reduce cost. Emphasis was placed on cost reduction, but significant feasibility concerns existed in several areas, and better design definition was required to establish feasibility and provide a better basis for cost estimates. Design definition and feasibility studies included the development of a labyrinth shield ring concept to prevent radiation streaming between the torus spool and the TF coil cryostat. The labyrinth shield concept which was developed reduced radiation streaming sufficiently to permit contact maintenance of the inboard EF coils. Various concepts of preventing arcing between adjacent shield sectors were also explored. It was concluded that installation of copper straps with molybdenum thermal radiation shields would provide the most reliable means of preventing arcing. Other design studies included torus spool electrical/structural concepts, test module shielding, torus seismic response, poloidal conditions in the magnets, disruption characteristics, and eddy current effects. These additional studies had no significant impact on cost but did confirm the feasibility of the basic FED Baseline concept.

  19. FED baseline engineering studies report

    International Nuclear Information System (INIS)

    Studies were carried out on the FED Baseline to improve design definition, establish feasibility, and reduce cost. Emphasis was placed on cost reduction, but significant feasibility concerns existed in several areas, and better design definition was required to establish feasibility and provide a better basis for cost estimates. Design definition and feasibility studies included the development of a labyrinth shield ring concept to prevent radiation streaming between the torus spool and the TF coil cryostat. The labyrinth shield concept which was developed reduced radiation streaming sufficiently to permit contact maintenance of the inboard EF coils. Various concepts of preventing arcing between adjacent shield sectors were also explored. It was concluded that installation of copper straps with molybdenum thermal radiation shields would provide the most reliable means of preventing arcing. Other design studies included torus spool electrical/structural concepts, test module shielding, torus seismic response, poloidal conditions in the magnets, disruption characteristics, and eddy current effects. These additional studies had no significant impact on cost but did confirm the feasibility of the basic FED Baseline concept

  20. Consumption of the Soluble Dietary Fibre Complex PolyGlycopleX® Reduces Glycaemia and Increases Satiety of a Standard Meal Postprandially

    Directory of Open Access Journals (Sweden)

    Vicky A. Solah

    2016-05-01

    Full Text Available The effect of consumption of PolyGlycopleX® (PGX® was compared to wheat dextrin (WD in combination with a standard meal, on postprandial satiety and glycaemia in a double-blind, randomised crossover trial, of 14 healthy subjects trained as a satiety panel. At each of six two-hour satiety sessions, subjects consumed one of three different test meals on two separate occasions. The test meals were: a standard meal plus 5 g PGX; a standard meal plus 4.5 g of PGX as softgels; and a standard meal plus 5 g of WD. Subjects recorded fullness using a labelled magnitude scale at 0, 15, 30, 45, 60, 90, and 120 min and the total area under the curve (AUC, mean fullness vs. time was calculated. The meals with PGX (in granular and softgel form gave higher satiety (AUC (477 ± 121 and 454 ± 242 cm·min, than the meal with WD (215 ± 261 cm·min (p < 0.001. Subjects had blood glucose levels measured after the meals with PGX (granules and WD. Glucose response (AUC was significantly lower (p < 0.001 after the PGX meal than for the WD meal.  The high viscosity reported for PGX is a likely mechanism behind the significant satiety and blood glucose modulating effects observed in this study.

  1. Long baseline experiments with LOFAR

    CERN Document Server

    Wucknitz, Olaf

    2010-01-01

    I present first results of LOFAR observations with international baselines. An important cornerstone was the detection of the first long-baseline fringes. Their analysis turns out to be extremely useful to investigate and solve a number of technical issues of the instrument. Crude maps of the sky are created from single-baseline delay/fringe-rate spectra and compared with a short-baseline synthesis map. First long-baseline LBA images are shown of the source 3C196, a bright quasar whose sub-components can only be resolved with the long baselines. The corresponding sub-arcsec HBA image does not show the same amount of details yet, but HBA results are expected to improve significantly very soon. The LBA long-baseline image of 3C196 comprises the highest-resolution radio map ever produced at this low frequency.

  2. Biofuels Baseline 2008

    Energy Technology Data Exchange (ETDEWEB)

    Hamelinck, C.; Koper, M.; Berndes, G.; Englund, O.; Diaz-Chavez, R.; Kunen, E.; Walden, D.

    2011-10-15

    The European Union is promoting the use of biofuels and other renewable energy in transport. In April 2009, the Renewable Energy Directive (2009/28/EC) was adopted that set a 10% target for renewable energy in transport in 2020. The directive sets several requirements to the sustainability of biofuels marketed in the frame of the Directive. The Commission is required to report to the European Parliament on a regular basis on a range of sustainability impacts resulting from the use of biofuels in the EU. This report serves as a baseline of information for regular monitoring on the impacts of the Directive. Chapter 2 discusses the EU biofuels market, the production and consumption of biofuels and international trade. It is derived where the feedstock for EU consumed biofuels originally come from. Chapter 3 discusses the biofuel policy framework in the EU and major third countries of supply. It looks at various policy aspects that are relevant to comply with the EU sustainability requirements. Chapter 4 discusses the environmental and social sustainability aspects associated with EU biofuels and their feedstock. Chapter 5 discusses the macro-economic effects that indirectly result from increased EU biofuels consumption, on commodity prices and land use. Chapter 6 presents country factsheets for main third countries that supplied biofuels to the EU market in 2008.

  3. Hydrogeology baseline study Aurora Mine

    International Nuclear Information System (INIS)

    A baseline hydrogeologic study was conducted in the area of Syncrude's proposed Aurora Mine in order to develop a conceptual regional hydrogeologic model for the area that could be used to understand groundwater flow conditions. Geologic information was obtained from over 2,000 coreholes and from data obtained between 1980 and 1996 regarding water level for the basal aquifer. A 3-D numerical groundwater flow model was developed to provide quantitative estimates of the potential environmental impacts of the proposed mining operations on the groundwater flow system. The information was presented in the context of a regional study area which encompassed much of the Athabasca Oil Sands Region, and a local study area which was defined by the lowlands of the Muskeg River Basin. Characteristics of the topography, hydrology, climate, geology, and hydrogeology of the region are described. The conclusion is that groundwater flow in the aquifer occurs mostly in a westerly direction beneath the Aurora Mine towards its inferred discharge location along the Athabasca River. Baseflow in the Muskeg River is mostly related to discharge from shallow surficial aquifers. Water in the river under baseflow conditions was fresh, of calcium-carbonate type, with very little indication of mineralization associated with deeper groundwater in the Aurora Mine area. 44 refs., 5 tabs., 31 figs

  4. Baseline assessment of physical characteristics, aquatic biota, and selected water-quality properties at the reach and mesohabitat scale for reaches of Big Cypress, Black Cypress, and Little Cypress Bayous, Big Cypress Basin, northeastern Texas, 2010–11

    Science.gov (United States)

    Braun, Christopher L.; Moring, James B.

    2013-01-01

    In 2010 and 2011, the U.S. Geological Survey (USGS), in cooperation with the Northeast Texas Municipal Water District and the Texas Commission on Environmental Quality, did a baseline assessment of physical characteristics and aquatic biota (fish and mussels) collected at the mesohabitat scale for reaches of Big Cypress, Black Cypress, and Little Cypress Bayous in the Big Cypress Basin in northeastern Texas, and measured selected water-quality properties in isolated pools in Black Cypress and Little Cypress. All of the data were collected in the context of prescribed environmental flows. The information acquired during the course of the study will support the long-term monitoring of biota in relation to environmental flow prescriptions for Big Cypress Bayou, Black Cypress Bayou, and Little Cypress Bayou. Data collection and analysis were done at mesohabitat- and reach-specific scales, where a mesohabitat is defined as a discrete area within a stream that exhibits unique depth, velocity, slope, substrate, and cover. Biological and physical characteristic data were collected from two sites on Big Cypress Bayou, and one site on both Black Cypress Bayou and Little Cypress Bayou. The upstream reach of Big Cypress Bayou (USGS station 07346015 Big Cypress Bayou at confluence of French Creek, Jefferson, Texas) is hereinafter referred to as the Big Cypress 02 site. The downstream site on Big Cypress Bayou (USGS station 07346017 Big Cypress Bayou near U.S. Highway 59 near Jefferson, Tex.) is hereinafter referred to as the Big Cypress 01 site and was sampled exclusively for mussels. The sites on Black Cypress Bayou (USGS station 07346044 Black Cypress Bayou near U.S. Highway 59 near Jefferson, Tex.) and Little Cypress Bayou (USGS station 07346071 Little Cypress Bayou near U.S. Highway 59 near Jefferson, Tex.) are hereinafter referred to as the Black Cypress and Little Cypress sites, respectively. A small range of streamflows was targeted for data collection, including a

  5. Increased postprandial glycaemia, insulinemia, and lipidemia after 10 weeks’ sucrose-rich diet compared to an artificially sweetened diet: a randomised controlled trial

    Directory of Open Access Journals (Sweden)

    Arne Astrup

    2011-07-01

    Full Text Available The importance of exchanging sucrose for artificial sweeteners on risk factors for developing diabetes and cardiovascular diseases is not yet clear. Objective: To investigate the effects of a diet high in sucrose versus a diet high in artificial sweeteners on fasting and postprandial metabolic profiles after 10 weeks.Healthy overweight subjects were randomised to consume drinks and foods sweetened with either sucrose (∼2 g/kg body weight (n = 12 or artificial sweeteners (n = 11 as supplements to their usual diet. Supplements were similar on the two diets and consisted of beverages (∼80 weight% and solid foods (yoghurts, marmalade, ice cream, stewed fruits. The rest of the diet was free of choice and ad libitum. Before (week 0 and after the intervention (week 10 fasting blood samples were drawn and in week 10, postprandial blood was sampled during an 8-hour meal test (breakfast and lunch.After 10 weeks postprandial glucose, insulin, lactate, triglyceride, leptin, glucagon, and GLP-1 were all significantly higher in the sucrose compared with the sweetener group. After adjusting for differences in body weight changes and fasting values (week 10, postprandial glucose, lactate, insulin, GIP, and GLP-1 were significantly higher and after further adjusting for differences in energy and sucrose intake, postprandial lactate, insulin, GIP, and GLP-1 levels were still significantly higher on the sucrose-rich diet.A sucrose-rich diet consumed for 10 weeks resulted in significant elevations of postprandial glycaemia, insulinemia, and lipidemia compared to a diet rich in artificial sweeteners in slightly overweight healthy subjects.

  6. Concurrent management of postprandial glycaemia and nutrient intake using glycaemic glucose equivalents, food composition data and computer-assisted meal design.

    Science.gov (United States)

    Monro, J A; Williams, M

    2000-06-01

    A computer system, called SERVE-NZ Nutririon Management System, for use in diabetes management, addresses the problem of concurrently controlling postprandial glycaemic response and nutrient intake in meals containing a number of foods, is described. It converts the weight and relative glycaemic potency of each food to its content of glycaemic glucose equivalents (GGE) - the amount of glucose theoretically inducing the same blood glucose response as would the specified quantity of food. Glycaemic glucose equivalents in a meal can be simply obtained by adding the GGE content of all foods in the meal to give a figure for the maximal glycaemic impact of the meal. Glycaemic glucose equivalents may be calculated using food composition databases that include available carbohydrate, common standard measure weights and glycaemic index values. If GGE is treated as a nutrient, an output of the total nutrient profile of a food or meal, and its glycaemic impact as GGE, can be obtained simultaneously. Application of a nutritional software system incorporating GGE values to management of glycaemic loadings and nutrient intakes over five meals within a day is demonstrated. The system may be a useful aid in self-management of glycaemia, as it will identify quantities of foods that can be consumed without exceeding the predetermined glucose tolerances of individuals. The graphical presentation of GGE and nutrient composition of meals may be a useful visual aid in educating clients with diabetes. The GGE values on food labels would provide easily understood guidance, not obtained from glycaemic index values, to the maximum number of items or quantity of a food that an individual should eat at a time. In its present basic form the calculation of GGE is most likely to slightly overestimate glycaemic impact, so it presents a worst-case prediction. PMID:24394390

  7. Baseline Familiarity in Lie Detection.

    Science.gov (United States)

    Feeley, Thomas H.; And Others

    1995-01-01

    Reports on a study in which subjects judged the veracity of truthful and deceptive communicators after viewing no, one, two, or four case-relevant baseline exposures (familiarity) of truthful communication. Finds a positive linear relationship between detection accuracy and amount of baseline familiarity. (SR)

  8. Program cost and schedule baseline

    International Nuclear Information System (INIS)

    The overall purpose of cost and schedule baseline management is to ensure that the Civilian Radioactive Waste Management (OCRWM) Program's cost and schedule plan are controlled in an orderly, efficient, and documented manner. Baseline control of the Program's cost and schedule will result in changes that only take place with OCRWM senior management approval, by way of the change control process. The Program Management System (PMS) Manual describes how the Program Cost and Schedule Baseline (PCSB) is integrated into the OCRWM management system. This PCSB document identifies the components of Program cost and schedule that will be subject to change control by DOE-Headquarters and establishes their baseline values. This document also summarizes the management components of the cost and schedule baseline, including reporting, monitoring, and corrective action. Detailed PCSB reporting, monitoring, and corrective action procedures will be issued as an Office of Program Administration and Resource Management (OPARM) administrative procedure. 9 figs

  9. Plutonium Immobilization Project Baseline Formulation

    Energy Technology Data Exchange (ETDEWEB)

    Ebbinghaus, B.

    1999-02-01

    A key milestone for the Immobilization Project (AOP Milestone 3.2a) in Fiscal Year 1998 (FY98) is the definition of the baseline composition or formulation for the plutonium ceramic form. The baseline formulation for the plutonium ceramic product must be finalized before the repository- and plant-related process specifications can be determined. The baseline formulation that is currently specified is given in Table 1.1. In addition to the baseline formulation specification, this report provides specifications for two alternative formulations, related compositional specifications (e.g., precursor compositions and mixing recipes), and other preliminary form and process specifications that are linked to the baseline formulation. The preliminary specifications, when finalized, are not expected to vary tremendously from the preliminary values given.

  10. 324 Building Baseline Radiological Characterization

    Energy Technology Data Exchange (ETDEWEB)

    R.J. Reeder, J.C. Cooper

    2010-06-24

    This report documents the analysis of radiological data collected as part of the characterization study performed in 1998. The study was performed to create a baseline of the radiological conditions in the 324 Building.

  11. Quivira NWR biological baseline data

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This dataset is biological baseline data for Quivira National Wildlife Refuge as of January 2016. It contains data on species found on the refuge, when and where...

  12. CASA Uno GPS orbit and baseline experiments

    Science.gov (United States)

    Schutz, B. E.; Ho, C. S.; Abusali, P. A. M.; Tapley, B. D.

    1990-01-01

    CASA Uno data from sites distributed in longitude from Australia to Europe have been used to determine orbits of the GPS satellites. The characteristics of the orbits determined from double difference phase have been evaluated through comparisons of two-week solutions with one-week solutions and by comparisons of predicted and estimated orbits. Evidence of unmodeled effects is demonstrated, particularly associated with the orbit planes that experience solar eclipse. The orbit accuracy has been assessed through the repeatability of unconstrained estimated baseline vectors ranging from 245 km to 5400 km. Both the baseline repeatability and the comparison with independent space geodetic methods give results at the level of 1-2 parts in 100,000,000. In addition, the Mojave/Owens Valley (245 km) and Kokee Park/Ft. Davis (5409 km) estimates agree with VLBI and SLR to better than 1 part in 100,000,000.

  13. Learning to Baseline Business Technology

    OpenAIRE

    David Gore; Marie D. Lee; Kimberly Hopper

    2013-01-01

    bills, sign multi-­‐year contracts, and make purchasing decisions without having an overall technology plan. That plan includes a technology baseline to fully assess existing technology. A CIO's goal is to align IT with business goals. Businesses must know total cost of ownership and the return on investment for all technology purchases and monthly costs. A business must also be able to manage technology assets and best utilize resources across the business. Teaching students to baseline tech...

  14. Population Study of Urban, Rural, and Semiurban Regions for the Detection of Endovascular Disease and Prevalence of Risk Factors and Holistic Intervention Study: Rationale, Study Design, and Baseline Characteristics of PURSE-HIS.

    Science.gov (United States)

    Thanikachalam, Sadagopan; Harivanzan, Vijayakumar; Mahadevan, Murugappapillai V; Murthy, J S N; Anbarasi, Chandrasekar; Saravanababu, Chidambaram S; Must, Aviva; Baliga, Ragavendra R; Abraham, William T; Thanikachalam, Mohan

    2015-12-01

    We designed and implemented the PURSE-HIS (Population Study of Urban, Rural and Semiurban Regions for the Detection of Endovascular Disease and Prevalence of Risk Factors and Holistic Intervention Study) to understand the prevalence and progression of subclinical and overt endovascular disease (EVD) and its risk factors in urban, semiurban, and rural communities in South India. The study is also designed to generate clinical evidence for effective, affordable, and sustainable community-specific intervention strategies to control risks factors for EVD. As of June 2012, 8,080 (urban: 2,221; semiurban: 2,821; rural: 3,038) participants >20 years of age were recruited using 2-stage cluster sampling. Baseline measurements included standard cardiovascular disease risk factors, sociodemographic factors, lifestyle habits, psychosocial factors, and nutritional assessment. Fasting blood samples were assayed for putative biochemical risk factors and urine samples for microalbuminuria. All nondiabetic participants underwent oral glucose tolerance test with blood and urine samples collected every 30 min for 2 h. Additional baseline measurements included flow-mediated brachial artery endothelial vasodilation, assessment of carotid intimal medial wall thickness using ultrasonography, screening for peripheral vascular disease using ankle and brachial blood pressures, hemodynamic screening using a high-fidelity applanation tonometry to measure central blood pressure parameters, and aortic pulse wave velocity. To assess prevalence of coronary artery disease, all participants underwent surface electrocardiography and documentation of ventricular wall motion abnormality and function using echocardiography imaging. To detect subclinical lesions, all eligible participants completed an exercise treadmill test. Prospectively, the study will assess progression of subclinical and overt EVD, including risk factor-outcome relation differences across communities. The study will also evaluate

  15. Rationale, design, and baseline characteristics of the Acetylcystein for Contrast-Induced nephropaThy (ACT Trial: a pragmatic randomized controlled trial to evaluate the efficacy of acetylcysteine for the prevention of contrast-induced nephropathy

    Directory of Open Access Journals (Sweden)

    2009-06-01

    Full Text Available Abstract Background Aceltylcysteine has been evaluated in several small trials as a means of reducing the risk of contrast-induced nephropathy (CIN, however systematic reviews of these studies do not provide conclusive answers. Therefore, a large randomized controlled trial (RCT is needed to provide a reliable answer as to whether acetylcysteine is effective in decreasing the risk of CIN in high-risk patients undergoing angiographic procedures. Methods ACT is a RCT of acetylcysteine versus placebo in 2,300 patients at-risk for CIN undergoing an intravascular angiographic procedure. The randomization list will be concealed. Participants, health care staff, investigators and outcome assessors will be blinded to whether patients receive acetylcysteine or placebo. All analysis will follow the intention-to-treat principle. The study drugs (acetylcysteine 1200 mg or placebo will be administered orally twice daily for two doses before and two doses after the procedure. The primary outcome is the occurrence of CIN, defined as a 25% elevation of serum creatinine above baseline between 48 and 96 hours after angiography. Discussion The first patient entered the trial on September, 2008. Up to April 7, 2009, 810 patients had been included in 35 centers. The mean age was 69 (Standard deviation: 10, 18% had a baseline serum creatinine >1.5 mg/dL, 57% were diabetics and 13% had a history of heart failure. The ongoing ACT Trial is the largest multicentre RCT that will determine whether acetylcysteine is effective in decreasing the risk of CIN in patients at risk undergoing angiography. Trial registration Clinicaltrials.gov NCT00736866

  16. SRP Baseline Hydrogeologic Investigation, Phase 3

    Energy Technology Data Exchange (ETDEWEB)

    Bledsoe, H.W.

    1988-08-01

    The SRP Baseline Hydrogeologic Investigation was implemented for the purpose of updating and improving the knowledge and understanding of the hydrogeologic systems underlying the SRP site. Phase III, which is discussed in this report, includes the drilling of 7 deep coreholes (sites P-24 through P-30) and the installation of 53 observation wells ranging in depth from approximately 50 ft to more than 970 ft below the ground surface. In addition to the collection of geologic cores for lithologic and stratigraphic study, samples were also collected for the determination of physical characteristics of the sediments and for the identification of microorganisms.

  17. Developing RESRAD-BASELINE for environmental baseline risk assessment

    International Nuclear Information System (INIS)

    RESRAD-BASELINE is a computer code developed at Argonne developed at Argonne National Laboratory for the US Department of Energy (DOE) to perform both radiological and chemical risk assessments. The code implements the baseline risk assessment guidance of the US Environmental Protection Agency (EPA 1989). The computer code calculates (1) radiation doses and cancer risks from exposure to radioactive materials, and (2) hazard indexes and cancer risks from exposure to noncarcinogenic and carcinogenic chemicals, respectively. The user can enter measured or predicted environmental media concentrations from the graphic interface and can simulate different exposure scenarios by selecting the appropriate pathways and modifying the exposure parameters. The database used by PESRAD-BASELINE includes dose conversion factors and slope factors for radionuclides and toxicity information and properties for chemicals. The user can modify the database for use in the calculation. Sensitivity analysis can be performed while running the computer code to examine the influence of the input parameters. Use of RESRAD-BASELINE for risk analysis is easy, fast, and cost-saving. Furthermore, it ensures in consistency in methodology for both radiological and chemical risk analyses

  18. CORonary Diet Intervention with Olive oil and cardiovascular PREVention study (the CORDIOPREV study): Rationale, methods, and baseline characteristics: A clinical trial comparing the efficacy of a Mediterranean diet rich in olive oil versus a low-fat diet on cardiovascular disease in coronary patients.

    Science.gov (United States)

    Delgado-Lista, Javier; Perez-Martinez, Pablo; Garcia-Rios, Antonio; Alcala-Diaz, Juan F; Perez-Caballero, Ana I; Gomez-Delgado, Francisco; Fuentes, Francisco; Quintana-Navarro, Gracia; Lopez-Segura, Fernando; Ortiz-Morales, Ana M; Delgado-Casado, Nieves; Yubero-Serrano, Elena M; Camargo, Antonio; Marin, Carmen; Rodriguez-Cantalejo, Fernando; Gomez-Luna, Purificacion; Ordovas, Jose M; Lopez-Miranda, Jose; Perez-Jimenez, Francisco

    2016-07-01

    Coronary heart disease (CHD) represents a major global health burden. However, despite the well-known influence that dietary habits exert over the progression of this disease, there are no well-established and scientifically sound dietary approaches to prevent the onset of clinical outcomes in secondary prevention. The objective of the CORonary Diet Intervention with Olive oil and cardiovascular PREVention study (CORDIOPREV study, clinical trials number NCT00924937) is to compare the ability of a Mediterranean diet rich in virgin olive oil versus a low-fat diet to influence the composite incidence of cardiovascular events after 7 years in subjects with documented CHD at baseline. For this purpose, we enrolled 1,002 coronary patients from Spain. Baseline assessment (2009-2012) included detailed interviews and measurements to assess dietary, social, and biological variables. Results of baseline characteristics: The CORDIOPREV study in Spain describes a population with a high body mass index (37.2% overweight and 56.3% obesity) and with a median of low-density lipoprotein cholesterol of 88.5 mg/dL (70.6% of the patients having study, which will test for the first time the efficacy of a Mediterranean diet rich in extra virgin olive oil as compared with a low-fat diet on the incidence of CHD recurrence in a long-term follow-up study. PMID:27297848

  19. Integrated Baseline Review (IBR) Handbook

    Science.gov (United States)

    2013-01-01

    An Integrated Baseline Review (IBR) is a review of a supplier?s Performance Measurement Baseline (PMB). It is conducted by Program/Project Managers and their technical staffs on contracts and in-house work requiring compliance with NASA Earned Value Management System (EVMS) policy as defined in program/project policy, NPR 7120.5, or in NASA Federal Acquisition Regulations. The IBR Handbook may also be of use to those responsible for preparing the Terms of Reference for internal project reviews. While risks may be identified and actions tracked as a result of the IBR, it is important to note that an IBR cannot be failed.

  20. Project FIT: Rationale, design and baseline characteristics of a school- and community-based intervention to address physical activity and healthy eating among low-income elementary school children

    Directory of Open Access Journals (Sweden)

    Oh Hyun J

    2011-07-01

    Full Text Available Abstract Background This paper describes Project FIT, a collaboration between the public school system, local health systems, physicians, neighborhood associations, businesses, faith-based leaders, community agencies and university researchers to develop a multi-faceted approach to promote physical activity and healthy eating toward the general goal of preventing and reducing childhood obesity among children in Grand Rapids, MI, USA. Methods/design There are four overall components to Project FIT: school, community, social marketing, and school staff wellness - all that focus on: 1 increasing access to safe and affordable physical activity and nutrition education opportunities in the schools and surrounding neighborhoods; 2 improving the affordability and availability of nutritious food in the neighborhoods surrounding the schools; 3 improving the knowledge, self-efficacy, attitudes and behaviors regarding nutrition and physical activity among school staff, parents and students; 4 impacting the 'culture' of the schools and neighborhoods to incorporate healthful values; and 5 encouraging dialogue among all community partners to leverage existing programs and introduce new ones. Discussion At baseline, there was generally low physical activity (70% do not meet recommendation of 60 minutes per day, excessive screen time (75% do not meet recommendation of rd-5th grade children (n = 403. Trial registration ClinicalTrials.gov NCT01385046

  1. Gliotransmission modulates baseline mechanical nociception

    Directory of Open Access Journals (Sweden)

    Foley Jeannine C

    2011-12-01

    Full Text Available Abstract Pain is a physiological and adaptive process which occurs to protect organisms from tissue damage and extended injury. Pain sensation beyond injury, however, is a pathological process which is poorly understood. Experimental models of neuropathic pain demonstrate that reactive astrocytes contribute to reduced nociceptive thresholds. Astrocytes release "gliotransmitters" such as D-serine, glutamate, and ATP, which is extracellularly hydrolyzed to adenosine. Adenosine 1 receptor activation in the spinal cord has anti-nociceptive effects on baseline pain threshold, but the source of the endogenous ligand (adenosine in the spinal cord is unknown. In this study we used a transgenic mouse model in which SNARE-mediated gliotransmission was selectively attenuated (called dnSNARE mice to investigate the role of astrocytes in mediating baseline nociception and the development of neuropathic pain. Under baseline conditions, immunostaining in the dorsal horn of the spinal cord showed astrocyte-specific transgene expression in dnSNARE mice, and no difference in expression levels of the astrocyte marker GFAP and the microglia marker Iba1 relative to wild-type mice. The Von Frey filament test was used to probe sensitivity to baseline mechanical pain thresholds and allodynia following the spared nerve injury model of neuropathic pain. DnSNARE mice exhibit a reduced nociceptive threshold in response to mechanical stimulation compared to wild-type mice under baseline conditions, but nociceptive thresholds following spared nerve injury were similar between dnSNARE and wild-types. This study is the first to provide evidence that gliotransmission contributes to basal mechanical nociception.

  2. Use of behavioral economics and social psychology to improve treatment of acute respiratory infections (BEARI): rationale and design of a cluster randomized controlled trial [1RC4AG039115-01] - study protocol and baseline practice and provider characteristics

    Science.gov (United States)

    2013-01-01

    -performing peers is reported back to the provider periodically by email. We enrolled 269 clinicians (practicing attending physicians or advanced practice nurses) in 49 participating clinic sites and collected baseline data. The primary outcome is the antibiotic prescribing rate for office visits with non-antibiotic-appropriate ARI diagnoses. Secondary outcomes will examine antibiotic prescribing more broadly. The 18-month intervention period will be followed by a one year follow-up period to measure persistence of effects after interventions cease. Discussion The ongoing BEARI Trial will evaluate the effectiveness of behavioral economic strategies in reducing inappropriate prescribing of antibiotics. Trials registration ClinicalTrials.gov: NCT01454947 PMID:23806017

  3. Baseline budgeting for continuous improvement.

    Science.gov (United States)

    Kilty, G L

    1999-05-01

    This article is designed to introduce the techniques used to convert traditionally maintained department budgets to baseline budgets. This entails identifying key activities, evaluating for value-added, and implementing continuous improvement opportunities. Baseline Budgeting for Continuous Improvement was created as a result of a newly named company president's request to implement zero-based budgeting. The president was frustrated with the mind-set of the organization, namely, "Next year's budget should be 10 to 15 percent more than this year's spending." Zero-based budgeting was not the answer, but combining the principles of activity-based costing and the Just-in-Time philosophy of eliminating waste and continuous improvement did provide a solution to the problem. PMID:10387778

  4. The Nuts and Bolts of Baseline Setting

    OpenAIRE

    Partnership for Market Readiness

    2012-01-01

    This document provides an overview of baseline setting for greenhouse gas (GHG) crediting mechanisms. The first section briefly explains the general purpose and objectives of setting a crediting mechanism baseline. The second section summarizes key policy considerations in defining and setting baselines. The final section covers important technical elements of baselines and provides an ove...

  5. Baseline LAW Glass Formulation Testing

    Energy Technology Data Exchange (ETDEWEB)

    Kruger, Albert A. [USDOE Office of River Protection, Richland, WA (United States); Mooers, Cavin [The Catholic University of America, Washington, DC (United States). Vitreous State Lab.; Bazemore, Gina [The Catholic University of America, Washington, DC (United States). Vitreous State Lab; Pegg, Ian L. [The Catholic University of America, Washington, DC (United States). Vitreous State Lab; Hight, Kenneth [The Catholic University of America, Washington, DC (United States). Vitreous State Lab; Lai, Shan Tao [The Catholic University of America, Washington, DC (United States). Vitreous State Lab; Buechele, Andrew [The Catholic University of America, Washington, DC (United States). Vitreous State Lab; Rielley, Elizabeth [The Catholic University of America, Washington, DC (United States). Vitreous State Lab; Gan, Hao [The Catholic University of America, Washington, DC (United States). Vitreous State Lab; Muller, Isabelle S. [The Catholic University of America, Washington, DC (United States). Vitreous State Lab; Cecil, Richard [The Catholic University of America, Washington, DC (United States). Vitreous State Lab

    2013-06-13

    The major objective of the baseline glass formulation work was to develop and select glass formulations that are compliant with contractual and processing requirements for each of the LAW waste streams. Other objectives of the work included preparation and characterization of glasses with respect to the properties of interest, optimization of sulfate loading in the glasses, evaluation of ability to achieve waste loading limits, testing to demonstrate compatibility of glass melts with melter materials of construction, development of glass formulations to support ILAW qualification activities, and identification of glass formulation issues with respect to contract specifications and processing requirements.

  6. Environmental Baseline File National Transportation

    International Nuclear Information System (INIS)

    This Environmental Baseline File summarizes and consolidates information related to the national-level transportation of commercial spent nuclear fuel. Topics addressed include: shipments of commercial spent nuclear fuel based on mostly truck and mostly rail shipping scenarios; transportation routing for commercial spent nuclear fuel sites and DOE sites; radionuclide inventories for various shipping container capacities; transportation routing; populations along transportation routes; urbanized area population densities; the impacts of historical, reasonably foreseeable, and general transportation; state-level food transfer factors; Federal Guidance Report No. 11 and 12 radionuclide dose conversion factors; and national average atmospheric conditions

  7. Baseline report for infiltration experiment

    Energy Technology Data Exchange (ETDEWEB)

    Aalto, P. (ed.); Helin, J.; Lindgren, S. (and others)

    2011-04-15

    An infiltration experiment to investigate potential changes in pH and redox conditions and in buffering capacity as well as the hydrogeochemical processes related to groundwater infiltration was started in late 2008 near ONKALO. The purpose of the experiment is to monitor the major infiltration flow path from ground surface into the upper part of ONKALO at a depth of about 50 to 100 m depending on the observations made during the experiment. Infiltration is activated by pumping a highly transmissive fracture zone (13-18.2 m) in drillhole OL-KR14, which is a part of the site scale hydrogeological feature. The influence of pumping is then monitored in drillholes, groundwater observation tubes and lysimeters through water, groundwater and microbiological samplings and hydrogeological measurements. Before the experiment was started, four new monitoring drillholes, nine groundwater observation tubes and nine lysimeters were installed in the test area and very detailed baseline field investigations were performed. In addition, information of existing investigation data from the area of interest was collected in together. The baseline field investigations included geological logging of the cores of new shallow drillholes, flow and transverse flow measurements in new shallow drillholes, SLUG measurements in groundwater observation tubes, head monitoring, groundwater and microbiological sampling and analysis from observation tubes, shallow drillholes and the pumping section in OL-KR14, water sampling and analysis from lysimeters and resistivity measurements of the overburden. The results of previously performed soil pit investigations and hydrogeological measurements carried out in the area of interest were also added to the investigation data. A detailed hydrogeological model of the experiment area was updated simultaneously with baseline field investigations; the previous version was presented in Pitkaenen et al. (2008). Apart from the field investigations, predictive

  8. Long-Baseline Neutrino Experiments

    CERN Document Server

    Diwan, M V; Qian, X; Rubbia, A

    2016-01-01

    We review long-baseline neutrino experiments in which neutrinos are detected after traversing macroscopic distances. Over such distances neutrinos have been found to oscillate among flavor states. Experiments with solar, atmospheric, reactor, and accelerator neutrinos have resulted in a coherent picture of neutrino masses and mixing of the three known flavor states. We will summarize the current best knowledge of neutrino parameters and phenomenology with our focus on the evolution of the experimental technique. We proceed from the first evidence produced by astrophysical neutrino sources to the current open questions and the goals of future research.

  9. Baseline report for infiltration experiment

    International Nuclear Information System (INIS)

    An infiltration experiment to investigate potential changes in pH and redox conditions and in buffering capacity as well as the hydrogeochemical processes related to groundwater infiltration was started in late 2008 near ONKALO. The purpose of the experiment is to monitor the major infiltration flow path from ground surface into the upper part of ONKALO at a depth of about 50 to 100 m depending on the observations made during the experiment. Infiltration is activated by pumping a highly transmissive fracture zone (13-18.2 m) in drillhole OL-KR14, which is a part of the site scale hydrogeological feature. The influence of pumping is then monitored in drillholes, groundwater observation tubes and lysimeters through water, groundwater and microbiological samplings and hydrogeological measurements. Before the experiment was started, four new monitoring drillholes, nine groundwater observation tubes and nine lysimeters were installed in the test area and very detailed baseline field investigations were performed. In addition, information of existing investigation data from the area of interest was collected in together. The baseline field investigations included geological logging of the cores of new shallow drillholes, flow and transverse flow measurements in new shallow drillholes, SLUG measurements in groundwater observation tubes, head monitoring, groundwater and microbiological sampling and analysis from observation tubes, shallow drillholes and the pumping section in OL-KR14, water sampling and analysis from lysimeters and resistivity measurements of the overburden. The results of previously performed soil pit investigations and hydrogeological measurements carried out in the area of interest were also added to the investigation data. A detailed hydrogeological model of the experiment area was updated simultaneously with baseline field investigations; the previous version was presented in Pitkaenen et al. (2008). Apart from the field investigations, predictive

  10. In-Space Manufacturing Baseline Property Development

    Science.gov (United States)

    Stockman, Tom; Schneider, Judith; Prater, Tracie; Bean, Quincy; Werkheiser, Nicki

    2016-01-01

    The In-Space Manufacturing (ISM) project at NASA Marshall Space Flight Center currently operates a 3D FDM (fused deposition modeling) printer onboard the International Space Station. In order to enable utilization of this capability by designer, the project needs to establish characteristic material properties for materials produced using the process. This is difficult for additive manufacturing since standards and specifications do not yet exist for these technologies. Due to availability of crew time, there are limitations to the sample size which in turn limits the application of the traditional design allowables approaches to develop a materials property database for designers. In this study, various approaches to development of material databases were evaluated for use by designers of space systems who wish to leverage in-space manufacturing capabilities. This study focuses on alternative statistical techniques for baseline property development to support in-space manufacturing.

  11. Baseline for coal powered plants

    International Nuclear Information System (INIS)

    Frequently, the cost performance of a specific power plant is measured by comparing the cost with the statistical average cost of plants through the industry. Unless all of the variables have been considered, this comparison may draw a misleading conclusion. The capital cost of a power plant varies with time (year of commercial operation and construction duration) due to the effect of inflation. Examine these cost data in detail revels that the variation in the cost is very wide. For example, published data shows that the ratio between the highest to the lowest cost per KW is more than 4 to 1 for the plants that commenced operation in 1984. The wide variation of the capital costs is explained below in relation to various influencing factors, differing conditions, and scope of work. This paper provides a defined baseline coal-fired plant, an analysis of its capital costs, and a discussion of the reasons for such wide variation

  12. TWRS privatization process technical baseline

    Energy Technology Data Exchange (ETDEWEB)

    Orme, R.M.

    1996-09-13

    The U.S. Department of Energy (DOE) is planning a two-phased program for the remediation of Hanford tank waste. Phase 1 is a pilot program to demonstrate the procurement of treatment services. The volume of waste treated during the Phase 1 is a small percentage of the tank waste. During Phase 2, DOE intends to procure treatment services for the balance of the waste. The TWRS Privatization Process Technical Baseline (PPTB) provides a summary level flowsheet/mass balance of tank waste treatment operations which is consistent with the tank inventory information, waste feed staging studies, and privatization guidelines currently available. The PPTB will be revised periodically as privatized processing concepts are crystallized.

  13. Integrated Baseline Review (IBR) Handbook

    Science.gov (United States)

    Fleming, Jon F.; Kehrer, Kristen C.

    2016-01-01

    The purpose of this handbook is intended to be a how-to guide to prepare for, conduct, and close-out an Integrated Baseline Review (IBR). It discusses the steps that should be considered, describes roles and responsibilities, tips for tailoring the IBR based on risk, cost, and need for management insight, and provides lessons learned from past IBRs. Appendices contain example documentation typically used in connection with an IBR. Note that these appendices are examples only, and should be tailored to meet the needs of individual projects and contracts. Following the guidance in this handbook will help customers and suppliers preparing for an IBR understand the expectations of the IBR, and ensure that the IBR meets the requirements for both in-house and contract efforts.

  14. Pinellas Plant Environmental Baseline Report

    Energy Technology Data Exchange (ETDEWEB)

    1997-06-01

    The Pinellas Plant has been part of the Department of Energy`s (DOE) nuclear weapons complex since the plant opened in 1957. In March 1995, the DOE sold the Pinellas Plant to the Pinellas County Industry Council (PCIC). DOE has leased back a large portion of the plant site to facilitate transition to alternate use and safe shutdown. The current mission is to achieve a safe transition of the facility from defense production and prepare the site for alternative uses as a community resource for economic development. Toward that effort, the Pinellas Plant Environmental Baseline Report (EBR) discusses the current and past environmental conditions of the plant site. Information for the EBR is obtained from plant records. Historical process and chemical usage information for each area is reviewed during area characterizations.

  15. 327 Building hazard baseline document

    International Nuclear Information System (INIS)

    This document identifies the hazards in the 327 Building at the time that a facility walk through was performed during FY99, presents a PHA of stabilization and deactivation activities, and provides a basis for the hazard evaluation and accident analysis that will be developed in the 327 Building Basis for Interim Operation (BIO). Activities addressed in this hazard baseline document include: (1) Stabilization and deactivation activities in preparation for eventual decommissioning of the 327 Building and the routine handling, processing, and shipment of waste to support these activities. (2) 324/327 Building Minimum Safe Project engineering and maintenance activities to maintain the building and systems viable--especially the Safety SSCs--to allow stabilization, deactivation, and waste handling activities with a minimum of risk to workers, the public, and the environment

  16. Atlantic NAD 83 SLA Baseline Tangents

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — This data set contains baseline tangent lines in ArcGIS shapefile format for the BOEM Atlantic Region. Baseline tangent lines are typically bay or river closing...

  17. Atlantic NAD 83 SLA Baseline Points

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — This data set contains baseline points in ArcGIS shapefile format for the BOEM Atlantic Region. Baseline points are the discrete coordinate points along the...

  18. Baseline Characteristics of the Korean Registry of Pulmonary Arterial Hypertension

    OpenAIRE

    Chung, Wook-Jin; Park, Yong Bum; Jeon, Chan Hong; Jung, Jo Won; Ko, Kwang-Phil; Choi, Sung Jae; Seo, Hye Sun; Lee, Jae Seung; Jung, Hae Ok; ,

    2015-01-01

    Despite recent advances in understanding of the pathobiology and targeted treatments of pulmonary arterial hypertension (PAH), epidemiologic data from large populations have been limited to western countries. The aim of the Korean Registry of Pulmonary Arterial Hypertension (KORPAH) was to examine the epidemiology and prognosis of Korean patients with PAH. KORPAH was designed as a nationwide, multicenter, prospective data collection using an internet webserver from September 2008 to December ...

  19. Baseline Graphite Characterization: First Billet

    Energy Technology Data Exchange (ETDEWEB)

    Mark C. Carroll; Joe Lords; David Rohrbaugh

    2010-09-01

    The Next Generation Nuclear Plant Project Graphite Research and Development program is currently establishing the safe operating envelope of graphite core components for a very high temperature reactor design. To meet this goal, the program is generating the extensive amount of quantitative data necessary for predicting the behavior and operating performance of the available nuclear graphite grades. In order determine the in-service behavior of the graphite for the latest proposed designs, two main programs are underway. The first, the Advanced Graphite Creep (AGC) program, is a set of experiments that are designed to evaluate the irradiated properties and behavior of nuclear grade graphite over a large spectrum of temperatures, neutron fluences, and compressive loads. Despite the aggressive experimental matrix that comprises the set of AGC test runs, a limited amount of data can be generated based upon the availability of space within the Advanced Test Reactor and the geometric constraints placed on the AGC specimens that will be inserted. In order to supplement the AGC data set, the Baseline Graphite Characterization program will endeavor to provide supplemental data that will characterize the inherent property variability in nuclear-grade graphite without the testing constraints of the AGC program. This variability in properties is a natural artifact of graphite due to the geologic raw materials that are utilized in its production. This variability will be quantified not only within a single billet of as-produced graphite, but also from billets within a single lot, billets from different lots of the same grade, and across different billets of the numerous grades of nuclear graphite that are presently available. The thorough understanding of this variability will provide added detail to the irradiated property data, and provide a more thorough understanding of the behavior of graphite that will be used in reactor design and licensing. This report covers the

  20. Biological baseline data Youngs Bay, Oregon, 1974

    Energy Technology Data Exchange (ETDEWEB)

    McMechan, K.J. (ed.); Higley, D.L.; Holton, R.L.

    1975-04-01

    This report presents biological baseline information gathered during the research project, Physical, Chemical and Biological Studies on Youngs Bay.'' Youngs Bay is a shallow embayment located on the south shore of the Columbia River, near Astoria, Oregon. Research on Youngs Bay was motivated by the proposed construction by Alumax Pacific Aluminum Corporation of an aluminum reduction plant at Warrenton, Oregon. The research was designed to provide biological baseline information on Youngs Bay in anticipation of potential harmful effects from plant effluents. The information collected concerns the kinds of animals found in the Youngs Bay area, and their distribution and seasonal patterns of abundance. In addition, information was collected on the feeding habits of selected fish species, and on the life history and behavioral characteristics of the most abundant benthic amphipod, Corophium salmonis. Sampling was conducted at approximately three-week intervals, using commonly accepted methods of animal collection. Relatively few stations were sampled for fish, because of the need to standardize conditions of capture. Data on fish capture are reported in terms of catch-per-unit effort by a particular sampling gear at a specific station. Methods used in sampling invertebrates were generally more quantitative, and allowed sampling at a greater variety of places, as well as a valid basis for the computation of densities. Checklists of invertebrate species and fish species were developed from these samples, and are referred to throughout the report. The invertebrate checklist is more specific taxonomically than are tables reporting invertebrate densities. This is because the methods employed in identification were more precise than those used in counts. 9 refs., 27 figs., 25 tabs.

  1. Lung VITAL: Rationale, design, and baseline characteristics of an ancillary study evaluating the effects of vitamin D and/or marine omega-3 fatty acid supplements on acute exacerbations of chronic respiratory disease, asthma control, pneumonia and lung function in adults.

    Science.gov (United States)

    Gold, Diane R; Litonjua, Augusto A; Carey, Vincent J; Manson, JoAnn E; Buring, Julie E; Lee, I-Min; Gordon, David; Walter, Joseph; Friedenberg, Georgina; Hankinson, John L; Copeland, Trisha; Luttmann-Gibson, Heike

    2016-03-01

    Laboratory and observational research studies suggest that vitamin D and marine omega-3 fatty acids may reduce risk for pneumonia, acute exacerbations of respiratory diseases including chronic obstructive lung disease (COPD) or asthma, and decline of lung function, but prevention trials with adequate dosing, adequate power, and adequate time to follow-up are lacking. The ongoing Lung VITAL study is taking advantage of a large clinical trial-the VITamin D and OmegA-3 TriaL (VITAL)-to conduct the first major evaluation of the influences of vitamin D and marine omega-3 fatty acid supplementation on pneumonia risk, respiratory exacerbation episodes, asthma control and lung function in adults. VITAL is a 5-yearU.S.-wide randomized, double-blind, placebo-controlled, 2×2 factorial trial of supplementation with vitamin D3 ([cholecalciferol], 2000IU/day) and marine omega-3 FA (Omacor® fish oil, eicosapentaenoic acid [EPA]+docosahexaenoic acid [DHA], 1g/day) for primary prevention of CVD and cancer among men and women, at baseline aged ≥50 and ≥55, respectively, with 5107 African Americans. In a subset of 1973 participants from 11 urban U.S. centers, lung function is measured before and two years after randomization. Yearly follow-up questionnaires assess incident pneumonia in the entire randomized population, and exacerbations of respiratory disease, asthma control and dyspnea in a subpopulation of 4314 randomized participants enriched, as shown in presentation of baseline characteristics, for respiratory disease, respiratory symptoms, and history of cigarette smoking. Self-reported pneumonia hospitalization will be confirmed by medical record review, and exacerbations will be confirmed by Center for Medicare and Medicaid Services data review. PMID:26784651

  2. 2016 Annual Technology Baseline (ATB)

    Energy Technology Data Exchange (ETDEWEB)

    Cole, Wesley; Kurup, Parthiv; Hand, Maureen; Feldman, David; Sigrin, Benjamin; Lantz, Eric; Stehly, Tyler; Augustine, Chad; Turchi, Craig; O' Connor, Patrick; Waldoch, Connor

    2016-09-01

    Consistent cost and performance data for various electricity generation technologies can be difficult to find and may change frequently for certain technologies. With the Annual Technology Baseline (ATB), National Renewable Energy Laboratory provides an organized and centralized dataset that was reviewed by internal and external experts. It uses the best information from the Department of Energy laboratory's renewable energy analysts and Energy Information Administration information for conventional technologies. The ATB will be updated annually in order to provide an up-to-date repository of current and future cost and performance data. Going forward, we plan to revise and refine the values using best available information. The ATB includes both a presentation with notes (PDF) and an associated Excel Workbook. The ATB includes the following electricity generation technologies: land-based wind; offshore wind; utility-scale solar PV; concentrating solar power; geothermal power; hydropower plants (upgrades to existing facilities, powering non-powered dams, and new stream-reach development); conventional coal; coal with carbon capture and sequestration; integrated gasification combined cycle coal; natural gas combustion turbines; natural gas combined cycle; conventional biopower. Nuclear laboratory's renewable energy analysts and Energy Information Administration information for conventional technologies. The ATB will be updated annually in order to provide an up-to-date repository of current and future cost and performance data. Going forward, we plan to revise and refine the values using best available information.

  3. Space Station-Baseline Configuration

    Science.gov (United States)

    1989-01-01

    In response to President Reagan's directive to NASA to develop a permanent marned Space Station within a decade, part of the State of the Union message to Congress on January 25, 1984, NASA and the Administration adopted a phased approach to Station development. This approach provided an initial capability at reduced costs, to be followed by an enhanced Space Station capability in the future. This illustration depicts the baseline configuration, which features a 110-meter-long horizontal boom with four pressurized modules attached in the middle. Located at each end are four photovoltaic arrays generating a total of 75-kW of power. Two attachment points for external payloads are provided along this boom. The four pressurized modules include the following: A laboratory and habitation module provided by the United States; two additional laboratories, one each provided by the European Space Agency (ESA) and Japan; and an ESA-provided Man-Tended Free Flyer, a pressurized module capable of operations both attached to and separate from the Space Station core. Canada was expected to provide the first increment of a Mobile Serving System.

  4. Multiproject baselines for evaluation of electric power projects

    Energy Technology Data Exchange (ETDEWEB)

    Sathaye, Jayant; Murtishaw, Scott; Price, Lynn; Lefranc, Maurice; Roy, Joyashree; Winkler, Harald; Spalding-Fecher, Randall

    2003-03-12

    Calculating greenhouse gas emissions reductions from climate change mitigation projects requires construction of a baseline that sets emissions levels that would have occurred without the project. This paper describes a standardized multiproject methodology for setting baselines, represented by the emissions rate (kg C/kWh), for electric power projects. A standardized methodology would reduce the transaction costs of projects. The most challenging aspect of setting multiproject emissions rates is determining the vintage and types of plants to include in the baseline and the stringency of the emissions rates to be considered, in order to balance the desire to encourage no- or low-carbon projects while maintaining environmental integrity. The criteria for selecting power plants to include in the baseline depend on characteristics of both the project and the electricity grid it serves. Two case studies illustrate the application of these concepts to the electric power grids in eastern India and South Africa. We use hypothetical, but realistic, climate change projects in each country to illustrate the use of the multiproject methodology, and note the further research required to fully understand the implications of the various choices in constructing and using these baselines.

  5. 324 Building Baseline Radiological Characterization

    International Nuclear Information System (INIS)

    This report documents the analysis of radiological data collected as part of the characterization study performed in 1998. The study was performed to create a baseline of the radiological conditions in the 324 Building. A total of 85 technical (100 square centimeter (cm2)) smears were collected from the Room 147 hoods, the Shielded Materials Facility (SMF), and the Radiochemical Engineering Cells (REC). Exposure rate readings (window open and window closed) were taken at a distance of 2.5 centimeters (cm) and 30 cm from the surface of each smear. Gross beta-gamma and alpha counts of each smear were also performed. The smear samples were analyzed by gamma energy analysis (GEA). Alpha energy analysis (AEA) and strontium-90 analysis were also performed on selected smears. GEA results for one or more samples reported the presence of manganese-54, cobalt-60, silver-108m antimony-125, cesium-134, cesium-137, europium-154, europium-155, and americium-241. AEA results reported the presence of plutonium-239/240, plutonium-238/241Am, curium-243/244, curium-242, and americium-243. Tables 5 through 9 present a summary by location of the estimated maximum removable and total contamination levels in the Room 147 hoods, the SMF, and the REC. The smear sample survey data and laboratory analytical results are presented in tabular form by sample in Appendix A. The Appendix A tables combine survey data documented in radiological survey reports found in Appendix B and laboratory analytical results reported in the 324 Building Physical and Radiological Characterization Study (Berk, Hill, and Landsman 1998), supplemented by the laboratory analytical results found in Appendix C.

  6. Hazard Baseline Downgrade Effluent Treatment Facility

    International Nuclear Information System (INIS)

    This Hazard Baseline Downgrade reviews the Effluent Treatment Facility, in accordance with Department of Energy Order 5480.23, WSRC11Q Facility Safety Document Manual, DOE-STD-1027-92, and DOE-EM-STD-5502-94. It provides a baseline grouping based on the chemical and radiological hazards associated with the facility. The Determination of the baseline grouping for ETF will aid in establishing the appropriate set of standards for the facility

  7. Hospital doctors' assessment of baseline spirometry.

    OpenAIRE

    Stephenson, N.; Morgan, R.; Abdel-Rahman-Abdel-Wahab, E.; Turnbull, C. J.

    1998-01-01

    Baseline spirometry is useful in diagnosing and managing pulmonary disease. In a questionnaire survey of 100 hospital doctors in two hospitals in the Mersey region, their views and ability to interpret baseline spirometry was assessed. Of the 70 doctors who responded, 65% felt they could accurately interpret baseline spirometry. However, only 12% accurately interpreted all five vitalographs in the questionnaire. The majority (72%) felt they had not had adequate teaching in interpretation of s...

  8. Longer-Baseline Telescopes Using Quantum Repeaters

    OpenAIRE

    Gottesman, Daniel; Jennewein, Thomas; Croke, Sarah

    2011-01-01

    We present an approach to building interferometric telescopes using ideas of quantum information. Current optical interferometers have limited baseline lengths, and thus limited resolution, because of noise and loss of signal due to the transmission of photons between the telescopes. The technology of quantum repeaters has the potential to eliminate this limit, allowing in principle interferometers with arbitrarily long baselines.

  9. IEA Wind Task 26: Offshore Wind Farm Baseline Documentation

    Energy Technology Data Exchange (ETDEWEB)

    Smart, Gavin [Offshore Renewable Energy Catapult, Blyth, Northumberland (United Kingdom); Smith, Aaron [National Renewable Energy Lab. (NREL), Golden, CO (United States); Warner, Ethan [National Renewable Energy Lab. (NREL), Golden, CO (United States); Sperstad, Iver Bakken [SINTEF Energy Research, Trondheim (Norway); Prinsen, Bob [Ecofys, Utrecht (Netherlands). TKI Wind Op Zee; Lacal-Arantegui, Roberto [European Commission Joint Research Centre (JRC), Brussels (Belgium)

    2016-06-02

    This document has been produced to provide the definition and rationale for the Baseline Offshore Wind Farm established within IEA Wind Task 26--Cost of Wind Energy. The Baseline has been developed to provide a common starting point for country comparisons and sensitivity analysis on key offshore wind cost and value drivers. The baseline project reflects an approximate average of the characteristics of projects installed between 2012 and 2014, with the project life assumed to be 20 years. The baseline wind farm is located 40 kilometres (km) from construction and operations and maintenance (O&M) ports and from export cable landfall. The wind farm consists of 100 4-megawatt (MW) wind turbines mounted on monopile foundations in an average water depth of 25 metres (m), connected by 33-kilovolt (kV) inter-array cables. The arrays are connected to a single offshore substation (33kV/220kV) mounted on a jacket foundation, with the substation connected via a single 220kV export cable to an onshore substation, 10km from landfall. The wind farm employs a port-based O&M strategy using crew-transfer vessels.

  10. TWRS technical baseline database manager definition document

    International Nuclear Information System (INIS)

    This document serves as a guide for using the TWRS Technical Baseline Database Management Systems Engineering (SE) support tool in performing SE activities for the Tank Waste Remediation System (TWRS). This document will provide a consistent interpretation of the relationships between the TWRS Technical Baseline Database Management software and the present TWRS SE practices. The Database Manager currently utilized is the RDD-1000 System manufactured by the Ascent Logic Corporation. In other documents, the term RDD-1000 may be used interchangeably with TWRS Technical Baseline Database Manager

  11. Monoenergetic neutrino beam for long baseline experiments

    International Nuclear Information System (INIS)

    In an electron capture process by a nucleus, emitted neutrinos are monoenergetic. We study a long baseline experiment with such a completely monoenergetic neutrino beam. This talk is based on Refs. 1 and 2. (author)

  12. Breton Island, Louisiana Baseline (Geographic, NAD83)

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — Breton Island, Louisiana Baseline (Geographic, NAD83) consists of vector line data that were input into the Digital Shoreline Analysis System (DSAS) version 4.0,...

  13. Long-Baseline Neutrino Oscillation Experiments

    OpenAIRE

    Feldman, G J; Hartnell, J.; T. Kobayashi

    2013-01-01

    A review of accelerator long-baseline neutrino oscillation experiments is provided, including all experiments performed to date and the projected sensitivity of those currently in progress. Accelerator experiments have played a crucial role in the confirmation of the neutrino oscillation phenomenon and in precision measurements of the parameters. With a fixed baseline and detectors providing good energy resolution, precise measurements of the ratio of distance/energy (L/E) on the scale of ind...

  14. Ultrasonic Techniques for Baseline-Free Damage Detection in Structures

    Science.gov (United States)

    Dutta, Debaditya

    This research presents ultrasonic techniques for baseline-free damage detection in structures in the context of structural health monitoring (SHM). Conventional SHM methods compare signals obtained from the pristine condition of a structure (baseline signals) with those from the current state, and relate certain changes in the signal characteristics to damage. While this approach has been successful in the laboratory, there are certain drawbacks of depending on baseline signals in real field applications. Data from the pristine condition are not available for most existing structures. Even if they are available, operational and environmental variations tend to mask the effect of damage on the signal characteristics. Most important, baseline measurements may become meaningless while assessing the condition of a structure after an extreme event such as an earthquake or a hurricane. Such events may destroy the sensors themselves and require installation of new sensors at different locations on the structure. Baseline-free structural damage detection can broaden the scope of SHM in the scenarios described above. A detailed discussion on the philosophy of baseline-free damage detection is provided in Chapter 1. Following this discussion, the research questions are formulated. The organization of this document and the major contributions of this research are also listed in this chapter. Chapter 2 describes a fully automated baseline-free technique for notch and crack detection in plates using a collocated pair of piezoelectric wafer transducers for measuring ultrasonic signals. Signal component corresponding to the damage induced mode-converted Lamb waves is extracted by processing the originally measured ultrasonic signals. The damage index is computed as a function of this mode-converted Lamb wave signal component. An over-determined system of Lamb wave measurements is used to find a least-square estimate of the measurement errors. This error estimate serves as the

  15. Rapidly Versus Slowly Progressing Patients With Alzheimer's Disease: Differences in Baseline Cognition.

    Science.gov (United States)

    Seidl, Jennifer N Travis; Massman, Paul J

    2016-06-01

    Rate of progression of cognitive deficits is variable among patients with Alzheimer's disease (AD). The purpose of the current study was to compare demographic characteristics and performance on neuropsychological measures at baseline evaluation between rapidly and slowly progressing patients. Participants were divided into 2 groups based on change in Alzheimer's Disease Assessment Scale-Cognitive subscale score from baseline to 2-year follow-up, and baseline performance was compared between the groups. Participants were 55 rapidly progressing and 55 slowly progressing patients with probable AD who had a follow-up evaluation 21 to 27 months after the baseline evaluation. The groups differed in age and initial Clinical Dementia Rating. Performance differed significantly between the groups on Verbal Series Attention Test time, Logical Memory I, Visual Reproduction I, Block Design, and Controlled Oral Word Association Test. Differences were found between rapidly and slowly progressing patients on baseline neuropsychological testing. PMID:26646117

  16. Atmospheric media effects on ARIES baseline determination

    Science.gov (United States)

    Wu, S. C.

    1981-01-01

    Different types of media effects on ARIES baseline determination are compared. The effectiveness of simple ionospheric calibration models are studied. To perform the covariance analysis, an ARIES observation sequence needs to be assumed. For the current purposes, the observation sequence is selected to be that of experiment 80D over the JPL/Goldstone baseline (approximately 180 km). This experiment consisted of 96 observations over a period of approximately 25 hours on March 25 to 26, 1980. It is found through covariance analyses that the component most sensitive to media depends heavily upon the correlation, between the two stations, of the media effects. It is also found that relying on the cancellation of ionospheric delays between the two ray paths of VLBI observations at S band results in a large error in baseline length determination. High degree removal of ionospheric effects is possible with a crude model, providing correct diurnal peak and minimum ionospheric levels are input.

  17. Baseline methodologies for clean development mechanism projects

    Energy Technology Data Exchange (ETDEWEB)

    Lee, M.K. (ed.); Shrestha, R.M.; Sharma, S.; Timilsina, G.R.; Kumar, S.

    2005-11-15

    The Kyoto Protocol and the Clean Development Mechanism (CDM) came into force on 16th February 2005 with its ratification by Russia. The increasing momentum of this process is reflected in more than 100 projects having been submitted to the CDM Executive Board (CDM-EB) for approval of the baselines and monitoring methodologies, which is the first step in developing and implementing CDM projects. A CDM project should result in a net decrease of GHG emissions below any level that would have resulted from other activities implemented in the absence of that CDM project. The 'baseline' defines the GHG emissions of activities that would have been implemented in the absence of a CDM project. The baseline methodology is the process/algorithm for establishing that baseline. The baseline, along with the baseline methodology, are thus the most critical element of any CDM project towards meeting the important criteria of CDM, which are that a CDM should result in 'real, measurable, and long term benefits related to the mitigation of climate change'. This guidebook is produced within the frame work of the United Nations Environment Programme (UNEP) facilitated 'Capacity Development for the Clean Development Mechanism (CD4CDM)' Project. This document is published as part of the projects effort to develop guidebooks that cover important issues such as project finance, sustainability impacts, legal framework and institutional framework. These materials are aimed to help stakeholders better understand the CDM and are believed to eventually contribute to maximize the effect of the CDM in achieving the ultimate goal of UNFCCC and its Kyoto Protocol. This Guidebook should be read in conjunction with the information provided in the two other guidebooks entitled, 'Clean Development Mechanism: Introduction to the CDM' and 'CDM Information and Guidebook' developed under the CD4CDM project. (BA)

  18. Baseline methodologies for clean development mechanism projects

    International Nuclear Information System (INIS)

    The Kyoto Protocol and the Clean Development Mechanism (CDM) came into force on 16th February 2005 with its ratification by Russia. The increasing momentum of this process is reflected in more than 100 projects having been submitted to the CDM Executive Board (CDM-EB) for approval of the baselines and monitoring methodologies, which is the first step in developing and implementing CDM projects. A CDM project should result in a net decrease of GHG emissions below any level that would have resulted from other activities implemented in the absence of that CDM project. The 'baseline' defines the GHG emissions of activities that would have been implemented in the absence of a CDM project. The baseline methodology is the process/algorithm for establishing that baseline. The baseline, along with the baseline methodology, are thus the most critical element of any CDM project towards meeting the important criteria of CDM, which are that a CDM should result in 'real, measurable, and long term benefits related to the mitigation of climate change'. This guidebook is produced within the frame work of the United Nations Environment Programme (UNEP) facilitated 'Capacity Development for the Clean Development Mechanism (CD4CDM)' Project. This document is published as part of the projects effort to develop guidebooks that cover important issues such as project finance, sustainability impacts, legal framework and institutional framework. These materials are aimed to help stakeholders better understand the CDM and are believed to eventually contribute to maximize the effect of the CDM in achieving the ultimate goal of UNFCCC and its Kyoto Protocol. This Guidebook should be read in conjunction with the information provided in the two other guidebooks entitled, 'Clean Development Mechanism: Introduction to the CDM' and 'CDM Information and Guidebook' developed under the CD4CDM project. (BA)

  19. The Fermilab short-baseline neutrino program

    International Nuclear Information System (INIS)

    The Fermilab short-baseline program is a multi-facetted one. Primarily it searches for evidence of sterile neutrinos as hinted at by the MiniBooNE and LSND results. It will also measure a whole suite of ν-Argon cross sections which will be very useful in future liquid argon long-baseline projects. The program is based on MicroBooNE, already installed in the beam line, the recently approved LAr1-ND and the future addition of the refurbished ICARUS

  20. Twenty-month follow-up of occlusal caries lesions deemed questionable at baseline

    DEFF Research Database (Denmark)

    Makhija, Sonia K; Gilbert, Gregg H; Funkhouser, Ellen;

    2014-01-01

    -three clinicians from The National Dental Practice-Based Research Network participated in this study, recording lesion characteristics at baseline and lesion status at 20 months. RESULTS: At baseline, 1,341 QOC lesions were examined; the treatment that was planned for 1,033 of those at baseline was monitoring...... (oral hygiene instruction, applying or prescribing fluoride or varnish, or both), and the remaining 308 received a sealant (n = 192) or invasive therapy (n = 116). At the 20-month visit, clinicians continued to monitor 927 (90 percent) of the 1,033 monitored lesions. Clinicians decided to seal 61 (6...

  1. Waste management project technical baseline description

    Energy Technology Data Exchange (ETDEWEB)

    Sederburg, J.P.

    1997-08-13

    A systems engineering approach has been taken to describe the technical baseline under which the Waste Management Project is currently operating. The document contains a mission analysis, function analysis, requirement analysis, interface definitions, alternative analysis, system definition, documentation requirements, implementation definitions, and discussion of uncertainties facing the Project.

  2. National Cyberethics, Cybersafety, Cybersecurity Baseline Study

    Science.gov (United States)

    Education Digest: Essential Readings Condensed for Quick Review, 2009

    2009-01-01

    This article presents findings from a study that explores the nature of the Cyberethics, Cybersafety, and Cybersecurity (C3) educational awareness policies, initiatives, curriculum, and practices currently taking place in the U.S. public and private K-12 educational settings. The study establishes baseline data on C3 awareness, which can be used…

  3. Geochemical modelling baseline compositions of groundwater

    DEFF Research Database (Denmark)

    Postma, Diederik Jan; Kjøller, Claus; Andersen, Martin Søgaard;

    2008-01-01

    Reactive transport models, were developed to explore the evolution in groundwater chemistry along the flow path in three aquifers; the Triassic East Midland aquifer (UK), the Miocene aquifer at Valreas (F) and the Cretaceous aquifer near Aveiro (P). All three aquifers contain very old groundwaters...... of the evolution in natural baseline properties in groundwater....

  4. Solid Waste Program technical baseline description

    Energy Technology Data Exchange (ETDEWEB)

    Carlson, A.B.

    1994-07-01

    The system engineering approach has been taken to describe the technical baseline under which the Solid Waste Program is currently operating. The document contains a mission analysis, function analysis, system definition, documentation requirements, facility and project bases, and uncertainties facing the program.

  5. The Geobiosphere Emergy Baseline: A synthesis

    Science.gov (United States)

    Following the Eighth Biennial Emergy Conference (January, 2014), the need for revisiting the procedures and assumptions used to compute the Geobiosphere Emergy Baseline (GEB) emerged as a necessity to strengthen the method of Emergy Accounting and remove sources of ambiguity and ...

  6. Waste management project technical baseline description

    International Nuclear Information System (INIS)

    A systems engineering approach has been taken to describe the technical baseline under which the Waste Management Project is currently operating. The document contains a mission analysis, function analysis, requirement analysis, interface definitions, alternative analysis, system definition, documentation requirements, implementation definitions, and discussion of uncertainties facing the Project

  7. Revisiting the relationship between baseline risk and risk under treatment

    Directory of Open Access Journals (Sweden)

    Nony Patrice

    2009-02-01

    Full Text Available Abstract Background In medical practice, it is generally accepted that the 'effect model' describing the relationship between baseline risk and risk under treatment is linear, i.e. 'relative risk' is constant. Absolute benefit is then proportional to a patient's baseline risk and the treatment is most effective among high-risk patients. Alternatively, the 'effect model' becomes curvilinear when 'odds ratio' is considered to be constant. However these two models are based on purely empirical considerations, and there is still no theoretical approach to support either the linear or the non-linear relation. Presentation of the hypothesis From logistic and sigmoidal Emax (Hill models, we derived a phenomenological model which includes the possibility of integrating both beneficial and harmful effects. Instead of a linear relation, our model suggests that the relationship is curvilinear i.e. the moderate-risk patients gain most from the treatment in opposition to those with low or high risk. Testing the hypothesis Two approaches can be proposed to investigate in practice such a model. The retrospective one is to perform a meta-analysis of clinical trials with subgroups of patients including a great range of baseline risks. The prospective one is to perform a large clinical trial in which patients are recruited according to several prestratified diverse and high risk groups. Implications of the hypothesis For the quantification of the treatment effect and considering such a model, the discrepancy between odds ratio and relative risk may be related not only to the level of risk under control conditions, but also to the characteristics of the dose-effect relation and the amount of dose administered. In the proposed approach, OR may be considered as constant in the whole range of Rc, and depending only on the intrinsic characteristics of the treatment. Therefore, OR should be preferred rather than RR to summarize information on treatment efficacy.

  8. Accelerated Best Basis Inventory Baselining Task

    International Nuclear Information System (INIS)

    The baselining effort was recently proposed to bring the Best-Basis Inventory (BBI) and Question No.8 of the Tank Interpretive Report (TIR) for all 177 tanks to the current standards and protocols and to prepare a TIR Question No.8 if one is not already available. This plan outlines the objectives and methodology of the accelerated BBI baselining task. BBI baselining meetings held during December 2000 resulted in a revised BBI methodology and an initial set of BBI creation rules to be used in the baselining effort. The objectives of the BBI baselining effort are to: (1) Provide inventories that are consistent with the revised BBI methodology and new BBI creation rules. (2) Split the total tank waste in each tank into six waste phases, as appropriate (Supernatant, saltcake solids, saltcake liquid, sludge solids, sludge liquid, and retained gas). In some tanks, the solids and liquid portions of the sludge and/or saltcake may be combined into a single sludge or saltcake phase. (3) Identify sampling events that are to be used for calculating the BBIs. (4) Update waste volumes for subsequent reconciliation with the Hanlon (2001) waste tank summary. (5) Implement new waste type templates. (6) Include any sample data that might have been unintentionally omitted in the previous BBI and remove any sample data that should not have been included. Sample data to be used in the BBI must be available on TWINS. (7) Ensure that an inventory value for each standard BBI analyte is provided for each waste component. Sample based inventories for supplemental BBI analytes will be included when available. (8) Provide new means and confidence interval reports if one is not already available and include uncertainties in reporting inventory values

  9. Mercury baseline levels in Flemish soils (Belgium)

    International Nuclear Information System (INIS)

    It is important to establish contaminant levels that are normally present in soils to provide baseline data for pollution studies. Mercury is a toxic element of concern. This study was aimed at assessing baseline mercury levels in soils in Flanders. In a previous study, mercury contents in soils in Oost-Vlaanderen were found to be significantly above levels reported elsewhere. For the current study, observations were extended over two more provinces, West-Vlaanderen and Antwerpen. Ranges of soil Hg contents were distinctly higher in the province Oost-Vlaanderen (interquartile range from 0.09 to 0.43 mg/kg) than in the other provinces (interquartile ranges from 0.7 to 0.13 and 0.7 to 0.15 mg/kg for West-Vlaanderen and Antwerpen, respectively). The standard threshold method was applied to separate soils containing baseline levels of Hg from the data. Baseline concentrations for Hg were characterised by a median of 0.10 mg Hg/kg dry soil, an interquartile range from 0.07 to 0.14 mg/kg and a 90% percentile value of 0.30 mg/kg. The influence of soil properties such as clay and organic carbon contents, and pH on baseline Hg concentrations was not important. Maps of the spatial distribution of Hg levels showed that the province Oost-Vlaanderen exhibited zones with systematically higher Hg soil contents. This may be related to the former presence of many small-scale industries employing mercury in that region. - Increased mercury levels may reflect human activity

  10. Joint Multi-baseline SAR Interferometry

    Directory of Open Access Journals (Sweden)

    S. Tebaldini

    2005-12-01

    Full Text Available We propose a technique to provide interferometry by combining multiple images of the same area. This technique differs from the multi-baseline approach in literature as (a it exploits all the images simultaneously, (b it performs a spectral shift preprocessing to remove most of the decorrelation, and (c it exploits distributed targets. The technique is mainly intended for DEM generation at centimetric accuracy, as well as for differential interferometry. The problem is framed in the contest of single-input multiple-output (SIMO channel estimation via the cross-relations (CR technique and the resulting algorithm provides significant improvements with respect to conventional approaches based either on independent analysis of single interferograms or multi-baselines phase analysis of single pixels of current literature, for those targets that are correlated in all the images, like for long-term coherent areas, or for acquisitions taken with a short revisit time (as those gathered with future satellite constellations.

  11. Multiple position borehole extensometer baseline algorithm

    International Nuclear Information System (INIS)

    This document provides the baseline algorithm for the Multiple Position Borehole Extensometers (MPBX's) used at the Near-Surface Test Facility (NSTF) as a part of the Rock Instrumentation System (RIS) for Full Scale Heater Tests (FS) number-sign 1 and number-sign 2. It represents the baseline information available at the time of publication. The purpose of this document is to state the algorithm to be used for the MPBX's at the NSTF, the basis for the equations, the method used to arrive at the constants in the equations, and to identify further instrument testing necessary to improve the understanding of the instrument's purpose in this high temperature, hard rock environment. 5 refs., 5 figs

  12. Dissipative Effect in Long Baseline Neutrino Experiments

    CERN Document Server

    Oliveira, Roberto L N

    2016-01-01

    The propagation of neutrinos in long baselines experiments may be influenced by dissipation effects. Using Lindblad Master Equation we evolve neutrinos taking into account these dissipative effects. The MSW and the dissipative effects may change the probabilities behavior. In this work, we show and explain how the behavior of the probabilities can change due to the decoherence and relaxation effects acting individually with the MSW effect. A new exotic peak appears in this case and we show the difference between the decoherence and relaxation effects in the appearance of this peak. We also adapt the usual approximate expression for survival and appearance probabilities with all possible decoherence effects. We suppose the baseline of DUNE and show how each decoherence parameters change the probabilities analyzing the possible modification using numeric and analytic approach.

  13. About the Baseline Surface Radiation Network

    OpenAIRE

    König-Langlo, Gert; Long, Chuck; Sieger, Rainer; Driemel, Amelie; Schmithüsen, Holger; Cohrs, Wolfgang; Raffel, Bonnie

    2015-01-01

    The Earth’s radiation budget is essential for driving the general circulation of the atmosphere and ocean and for building the main conditions for the Earth's climate system. To detect changes in the Earth’s surface radiation field the Baseline Surface Radiation Network (BSRN) and its central archive - the World Radiation Monitoring Center (WRMC) - was created in 1992. BSRN is a project of the Data and Assessments Panel of the Global Energy and Water Cycle Experiment (GEWEX) under the umbr...

  14. Efficient Wide Baseline Structure from Motion

    Science.gov (United States)

    Michelini, Mario; Mayer, Helmut

    2016-06-01

    This paper presents a Structure from Motion approach for complex unorganized image sets. To achieve high accuracy and robustness, image triplets are employed and (an approximate) camera calibration is assumed to be known. The focus lies on a complete linking of images even in case of large image distortions, e.g., caused by wide baselines, as well as weak baselines. A method for embedding image descriptors into Hamming space is proposed for fast image similarity ranking. The later is employed to limit the number of pairs to be matched by a wide baseline method. An iterative graph-based approach is proposed formulating image linking as the search for a terminal Steiner minimum tree in a line graph. Finally, additional links are determined and employed to improve the accuracy of the pose estimation. By this means, loops in long image sequences are implicitly closed. The potential of the proposed approach is demonstrated by results for several complex image sets also in comparison with VisualSFM.

  15. Guidance on Port Biological Baseline Surveys (PBBS)

    Digital Repository Service at National Institute of Oceanography (India)

    Awad, A.; Haag, F.; Anil, A.C.; Abdulla, A.

    =UTF-8 GUIDANCE ON PORT BIOLOGICAL BASELINE SURVEYS (PBBS) GloBallast Monograph Series No.22 Partnerships GloBallast www.imo.org More Information? GloBallast Partnerships Programme Coordination Unit International Maritime Organization 4... Albert Embankment London SE1 7SR United Kingdom Tel: +44 (0)20 7463 4215 Fax: +44 (0)20 7587 3210 http://globallast.imo.org GloBallast Partnerships - Home http://globallast.imo.org http://kaywa.me/5uuuY Download the Kaywa QR Code Reader (App Store...

  16. Environmental Baseline File for National Transportation

    International Nuclear Information System (INIS)

    This Environmental Baseline File summarizes and consolidates information related to the national-level transportation of commercial spent nuclear fuel. Topics address include: shipments of commercial spent nuclear fuel based on mostly truck and mostly rail shipping scenarios; transportation routing for commercial spent nuclear fuel sites and DOE sites; radionuclide inventories for various shipping container capacities; transportation routing; populations along transportation routes; urbanized area population densities; the impacts of historical, reasonably foreseeable, and general transportation; state-level food transfer factors; Federal Guidance Report No. 11 and 12 radionuclide dose conversion factors; and national average atmospheric conditions

  17. Baseline scenarios of global environmental change

    International Nuclear Information System (INIS)

    This paper presents three baseline scenarios of no policy action computed by the IMAGE2 model. These scenarios cover a wide range of coupled global change indicators, including: energy demand and consumption; food demand, consumption, and production; changes in land cover including changes in extent of agricultural land and forest; emissions of greenhouse gases and ozone precursors; and climate change and its impacts on sea level rise, crop productivity and natural vegetation. Scenario information is available for the entire world with regional and grid scale detail, and covers from 1970 to 2100. (author)

  18. Very Long Baseline Interferometry with the SKA

    Science.gov (United States)

    Paragi, Z.; Godfrey, L.; Reynolds, C.; Rioja, M. J.; Deller, A.; Zhang, B.; Gurvits, L.; Bietenholz, M.; Szomoru, A.; Bignall, H. E.; Boven, P.; Charlot, P.; Dodson, R.; Frey, S.; Garrett, M. A.; Imai, H.; Lobanov, A.; Reid, M. J.; Ros, E.; van Langevelde, H. J.; Zensus, A. J.; Zheng, X. W.; Alberdi, A.; Agudo, I.; An, T.; Argo, M.; Beswick, R.; Biggs, A.; Brunthaler, A.; Campbell, B.; Cimo, G.; Colomer, F.; Corbel, S.; Conway, J. E.; Cseh, D.; Deane, R.; Falcke, H. D. E.; Gawronski, M.; Gaylard, M.; Giovannini, G.; Giroletti, M.; Goddi, C.; Goedhart, S.; Gómez, J. L.; Gunn, A.; Kharb, P.; Kloeckner, H. R.; Koerding, E.; Kovalev, Y.; Kunert-Bajraszewska, M.; Lindqvist, M.; Lister, M.; Mantovani, F.; Marti-Vidal, I.; Mezcua, M.; McKean, J.; Middelberg, E.; Miller-Jones, J. C. A.; Moldon, J.; Muxlow, T.; O'Brien, T.; Perez-Torres, M.; Pogrebenko, S. V.; Quick, J.; Rushton, A.; Schilizzi, R.; Smirnov, O.; Sohn, B. W.; Surcis, G.; Taylor, G. B.; Tingay, S.; Tudose, V. M.; van der Horst, A.; van Leeuwen, J.; Venturi, T.; Vermeulen, R.; Vlemmings, W. H. T.; de Witt, A.; Wucknitz, O.; Yang, J.; Gabänyi, K.; Jung, T.

    2015-04-01

    Adding VLBI capability to the SKA arrays will greatly broaden the science of the SKA, and is feasible within the current specifications. SKA-VLBI can be initially implemented by providing phased-array outputs for SKA1-MID and SKA1-SUR and using these extremely sensitive stations with other radio telescopes, and in SKA2 by realising a distributed configuration providing baselines up to thousands of km, merging it with existing VLBI networks. The motivation for and the possible realization of SKA-VLBI is described in this paper.

  19. Very Long Baseline Interferometry with the SKA

    CERN Document Server

    Paragi, Zsolt; Reynolds, Cormac; Rioja, Maria; Deller, Adam; Zhang, Bo; Gurvits, Leonid; Bietenholz, Michael; Szomoru, Arpad; Bignall, Hayley; Boven, Paul; Charlot, Patrick; Dodson, Richard; Frey, Sandor; Garrett, Michael; Imai, Hiroshi; Lobanov, Andrei; Reid, Mark; Ros, Eduardo; van Langevelde, Huib; Zensus, J Anton; Zheng, Xing Wu; Alberdi, Antxon; Agudo, Ivan; An, Tao; Argo, Megan; Beswick, Rob; Biggs, Andy D; Brunthaler, Andreas; Campbell, Robert M; Cimo, Giuseppe; Colomer, Francisco; Corbel, Stephane; Conway, John; Cseh, David; Deane, Roger; Falcke, Heino; Gabanyi, Krisztina; Gawronski, Marcin; Gaylard, Michael; Giovannini, Gabriele; Giroletti, Marcello; Goddi, Ciriaco; Goedhart, Sharmila; Gomez, Jose L; Gunn, Alastair; Jung, Taehyun; Kharb, Preeti; Klockner, Hans-Rainer; Kording, Elmar; Kovalev, Yurii Yu; Kunert-Bajraszewska, Magdalena; Lindqvist, Michael; Lister, Matt; Mantovani, Franco; Marti-Vidal, Ivan; Mezcua, Mar; McKean, John; Middelberg, Enno; Miller-Jones, James; Moldon, Javier; Muxlow, Tom; O'Brien, Tim; Pérez-Torres, Miguel; Pogrebenko, Sergei; Quick, Jonathan; Rushton, Anthony P; Schilizzi, Richard; Smirnov, Oleg; Sohn, Bong Won; Surcis, Gabriele; Taylor, Greg; Tingay, Steven; Tudose, Valeriu; van der Horst, Alexander; van Leeuwen, Joeri; Venturi, Tiziana; Vermeulen, Rene; Vlemmings, Wouter; de Witt, Aletha; Wucknitz, Olaf; Yang, Jun

    2014-01-01

    Adding VLBI capability to the SKA arrays will greatly broaden the science of the SKA, and is feasible within the current specifications. SKA-VLBI can be initially implemented by providing phased-array outputs for SKA1-MID and SKA1-SUR and using these extremely sensitive stations with other radio telescopes, and in SKA2 by realising a distributed configuration providing baselines up to thousands of km, merging it with existing VLBI networks. The motivation for and the possible realization of SKA-VLBI is described in this paper.

  20. Precision Calibration of Radio Interferometers Using Redundant Baselines

    CERN Document Server

    Liu, Adrian; Morrison, Scott; Lutomirski, Andrew; Zaldarriaga, Matias

    2010-01-01

    Growing interest in 21 cm tomography has led to the design and construction of broadband radio interferometers with low noise, moderate angular resolution, high spectral resolution, and wide fields of view. With characteristics somewhat different from traditional radio instruments, these interferometers will require new calibration techniques in order to reach their design sensitivities. We propose a calibration method that eliminates the need for calibrator point sources by taking advantage of the fact that many of these new instruments possess a large number of redundant baselines. The method is unbiased and the computational cost of the calibration is much less than that for the standard initial step of computing interferometric correlations. We also develop a general calibration formalism that includes both our method and traditional calibration methods as special cases, and show how slight deviations from perfect redundancy and coplanarity can be taken into account.

  1. Vegetation baseline report : Connacher great divide project

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-08-01

    This baseline report supported an application by Connacher Oil and Gas Ltd. to the Alberta Energy and Utilities Board (EUB) and Alberta Environment (AENV) for the Great Divide Steam Assisted Gravity Drainage (SAGD) Project. The goal of the report was to document the distribution and occurrence of ecosite phases and wetland classes in the project footprint as well as to document the distribution of rare plants; rare plant communities: and intrusive species and old growth communities, including species of management concern. A methodology of the baseline report was presented, including details of mapping and field surveys. Six vegetation types in addition to the disturbed land unit were identified in the project footprint and associated buffer. It was noted that all vegetation types are common for the boreal forest natural regions. Several species of management concern were identified during the spring rare plant survey, including rare bryophytes and non-native or invasive species. Mitigation was identified through a slight shift of the footprint, transplant of appropriate bryophyte species and implementation of a weed management plan. It was noted that results of future surveys for rare plants will be submitted upon completion. It was concluded that the effects of the project on existing vegetation is expected to be low because of the small footprint, prior disturbance history, available mitigation measures and conservation and reclamation planning. 27 refs., 5 tabs., 4 figs.

  2. Baseline tests for arc melter vitrification of INEL buried wastes. Volume II: Baseline test data appendices

    Energy Technology Data Exchange (ETDEWEB)

    Oden, L.L.; O`Conner, W.K.; Turner, P.C.; Soelberg, N.R.; Anderson, G.L.

    1993-11-19

    This report presents field results and raw data from the Buried Waste Integrated Demonstration (BWID) Arc Melter Vitrification Project Phase 1 baseline test series conducted by the Idaho National Engineering Laboratory (INEL) in cooperation with the U.S. Bureau of Mines (USBM). The baseline test series was conducted using the electric arc melter facility at the USBM Albany Research Center in Albany, Oregon. Five different surrogate waste feed mixtures were tested that simulated thermally-oxidized, buried, TRU-contaminated, mixed wastes and soils present at the INEL. The USBM Arc Furnace Integrated Waste Processing Test Facility includes a continuous feed system, the arc melting furnace, an offgas control system, and utilities. The melter is a sealed, 3-phase alternating current (ac) furnace approximately 2 m high and 1.3 m wide. The furnace has a capacity of 1 metric ton of steel and can process as much as 1,500 lb/h of soil-type waste materials. The surrogate feed materials included five mixtures designed to simulate incinerated TRU-contaminated buried waste materials mixed with INEL soil. Process samples, melter system operations data and offgas composition data were obtained during the baseline tests to evaluate the melter performance and meet test objectives. Samples and data gathered during this program included (a) automatically and manually logged melter systems operations data, (b) process samples of slag, metal and fume solids, and (c) offgas composition, temperature, velocity, flowrate, moisture content, particulate loading and metals content. This report consists of 2 volumes: Volume I summarizes the baseline test operations. It includes an executive summary, system and facility description, review of the surrogate waste mixtures, and a description of the baseline test activities, measurements, and sample collection. Volume II contains the raw test data and sample analyses from samples collected during the baseline tests.

  3. Tightly coupled long baseline/ultra-short baseline integrated navigation system

    Science.gov (United States)

    Batista, Pedro; Silvestre, Carlos; Oliveira, Paulo

    2016-06-01

    This paper proposes a novel integrated navigation filter based on a combined long baseline/ultra short baseline acoustic positioning system with application to underwater vehicles. With a tightly coupled structure, the position, linear velocity, attitude, and rate gyro bias are estimated, considering the full nonlinear system dynamics without resorting to any algebraic inversion or linearisation techniques. The resulting solution ensures convergence of the estimation error to zero for all initial conditions, exponentially fast. Finally, it is shown, under simulation environment, that the filter achieves very good performance in the presence of sensor noise.

  4. Accounting for baseline differences and measurement error in the analysis of change over time.

    Science.gov (United States)

    Braun, Julia; Held, Leonhard; Ledergerber, Bruno

    2014-01-15

    If change over time is compared in several groups, it is important to take into account baseline values so that the comparison is carried out under the same preconditions. As the observed baseline measurements are distorted by measurement error, it may not be sufficient to include them as covariate. By fitting a longitudinal mixed-effects model to all data including the baseline observations and subsequently calculating the expected change conditional on the underlying baseline value, a solution to this problem has been provided recently so that groups with the same baseline characteristics can be compared. In this article, we present an extended approach where a broader set of models can be used. Specifically, it is possible to include any desired set of interactions between the time variable and the other covariates, and also, time-dependent covariates can be included. Additionally, we extend the method to adjust for baseline measurement error of other time-varying covariates. We apply the methodology to data from the Swiss HIV Cohort Study to address the question if a joint infection with HIV-1 and hepatitis C virus leads to a slower increase of CD4 lymphocyte counts over time after the start of antiretroviral therapy. PMID:23900718

  5. Pentek concrete scabbling system: Baseline report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-31

    The Pentek scabbling technology was tested at Florida International University (FIU) and is being evaluated as a baseline technology. This report evaluates it for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The Pentek concrete scabbling system consisted of the MOOSE{reg_sign}, SQUIRREL{reg_sign}-I, and SQUIRREL{reg_sign}-III scabblers. The scabblers are designed to scarify concrete floors and slabs using cross-section, tungsten carbide tipped bits. The bits are designed to remove concrete in 318 inch increments. The bits are either 9-tooth or demolition type. The scabblers are used with a vacuum system designed to collect and filter the concrete dust and contamination that is removed from the surface. The safety and health evaluation during the human factors assessment focused on two main areas: noise and dust.

  6. Intensity interferometry: Optical imaging with kilometer baselines

    CERN Document Server

    Dravins, Dainis

    2016-01-01

    Optical imaging with microarcsecond resolution will reveal details across and outside stellar surfaces but requires kilometer-scale interferometers, challenging to realize either on the ground or in space. Intensity interferometry, electronically connecting independent telescopes, has a noise budget that relates to the electronic time resolution, circumventing issues of atmospheric turbulence. Extents up to a few km are becoming realistic with arrays of optical air Cherenkov telescopes (primarily erected for gamma-ray studies), enabling an optical equivalent of radio interferometer arrays. Pioneered by Hanbury Brown and Twiss, digital versions of the technique have now been demonstrated, reconstructing diffraction-limited images from laboratory measurements over hundreds of optical baselines. This review outlines the method from its beginnings, describes current experiments, and sketches prospects for future observations.

  7. The WITCH Model. Structure, Baseline, Solutions.

    Energy Technology Data Exchange (ETDEWEB)

    Bosetti, V.; Massetti, E.; Tavoni, M.

    2007-07-01

    WITCH - World Induced Technical Change Hybrid - is a regionally disaggregated hard link hybrid global model with a neoclassical optimal growth structure (top down) and an energy input detail (bottom up). The model endogenously accounts for technological change, both through learning curves affecting prices of new vintages of capital and through R and D investments. The model features the main economic and environmental policies in each world region as the outcome of a dynamic game. WITCH belongs to the class of Integrated Assessment Models as it possesses a climate module that feeds climate changes back into the economy. In this paper we provide a thorough discussion of the model structure and baseline projections. We report detailed information on the evolution of energy demand, technology and CO2 emissions. Finally, we explicitly quantifiy the role of free riding in determining the emissions scenarios. (auth)

  8. Global Nuclear Energy Partnership Waste Treatment Baseline

    Energy Technology Data Exchange (ETDEWEB)

    Gombert, Dirk; Ebert, William; Marra, James; Jubin, Robert; Vienna, John [Idaho National laboratory, 2525 Fremont Ave., Idaho Falls, ID 83402 (United States)

    2008-07-01

    The Global Nuclear Energy Partnership (GNEP) program is designed to demonstrate that a proliferation-resistant and sustainable integrated nuclear fuel cycle can be commercialized and used internationally. Alternative stabilization concepts for byproducts and waste streams generated by fuel recycling processes were evaluated and a baseline set of waste forms was recommended for the safe disposition of waste streams. Specific waste forms are recommended based on the demonstrated or expected commercial practicability and technical maturity of the processes needed to make the waste forms, and expected performance of the waste form materials when disposed. Significant issues remain in developing technologies to process some of the wastes into the recommended waste forms, and a detailed analysis of technology readiness may lead to the choice of a different waste form than what is recommended herein. Evolving regulations could also affect the selection of waste forms. (authors)

  9. Global Nuclear Energy Partnership Waste Treatment Baseline

    Energy Technology Data Exchange (ETDEWEB)

    Dirk Gombert; William Ebert; James Marra; Robert Jubin; John Vienna

    2008-05-01

    The Global Nuclear Energy Partnership program (GNEP) is designed to demonstrate a proliferation-resistant and sustainable integrated nuclear fuel cycle that can be commercialized and used internationally. Alternative stabilization concepts for byproducts and waste streams generated by fuel recycling processes were evaluated and a baseline of waste forms was recommended for the safe disposition of waste streams. Waste forms are recommended based on the demonstrated or expected commercial practicability and technical maturity of the processes needed to make the waste forms, and performance of the waste form materials when disposed. Significant issues remain in developing technologies to process some of the wastes into the recommended waste forms, and a detailed analysis of technology readiness and availability may lead to the choice of a different waste form than what is recommended herein. Evolving regulations could also affect the selection of waste forms.

  10. Global Nuclear Energy Partnership Waste Treatment Baseline

    International Nuclear Information System (INIS)

    The Global Nuclear Energy Partnership (GNEP) program is designed to demonstrate that a proliferation-resistant and sustainable integrated nuclear fuel cycle can be commercialized and used internationally. Alternative stabilization concepts for byproducts and waste streams generated by fuel recycling processes were evaluated and a baseline set of waste forms was recommended for the safe disposition of waste streams. Specific waste forms are recommended based on the demonstrated or expected commercial practicability and technical maturity of the processes needed to make the waste forms, and expected performance of the waste form materials when disposed. Significant issues remain in developing technologies to process some of the wastes into the recommended waste forms, and a detailed analysis of technology readiness may lead to the choice of a different waste form than what is recommended herein. Evolving regulations could also affect the selection of waste forms. (authors)

  11. An automated approach to configuration baseline documentation

    International Nuclear Information System (INIS)

    This paper presents Public Service Electric and Gas Company's (PSE and G's) automated approach to configuration base-line documentation (CBD) for Salem units 1 and 2 and Hope Creek. The CBD project is a proactive project, similar to what is commonly termed a design basis documentation program in the nuclear utility industry. The data information management system (DIMS) element of the CBD project is expected to automate the CBD development, review/approval, control, maintenance, and distribution of CBD and the subsequent integration of the CBD into the day-to-day design processes of PSE and G's nuclear engineering department. The DIMS project scope emphasizes streamlined, swift, and accurate design information retrieval system hardware and software; proper and controlled screening of stored design information; legible storage of design information; and more efficient and user-friendly information handling. This paper discusses the selection and implementation of an integrated optical imaging and textual search technology

  12. Steganography Based on Baseline Sequential JPEG Compression

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Information hiding in Joint Photographic Experts Group (JPEG) compressed images are investigated in this paper. Quantization is the source of information loss in JPEG compression process. Therefore, information hidden in images is probably destroyed by JPEG compression. This paper presents an algorithm to reliably embed information into the JPEG bit streams in the process of JPEG encoding. Information extraction is performed in the process of JPEG decoding. The basic idea of our algorithm is to modify the quantized direct current (DC) coefficients and non-zero alternating current (AC) coefficients to represent one bit information (0 or 1). Experimental results on gray images using baseline sequential JPEG encoding show that the cover images (images without secret information) and the stego-images (images with secret information) are perceptually indiscernible.

  13. Sterile neutrino fits to short baseline data

    Science.gov (United States)

    Collin, G. H.; Argüelles, C. A.; Conrad, J. M.; Shaevitz, M. H.

    2016-07-01

    Neutrino oscillation models involving extra mass eigenstates beyond the standard three (3 + N) are fit to global short baseline experimental data. We find that 3 + 1 has a best fit of Δ m412 = 1.75 eV2 with a Δ χnull-min2 (dof) of 52.34 (3). The 3 + 2 fit has a Δ χnull-min2 (dof) of 56.99 (7). For the first time, we show Bayesian credible intervals for a 3 + 1 model. These are found to be in agreement with frequentist intervals. The results of these new fits favor a higher Δm2 value than previous studies, which may have an impact on future sterile neutrino searches such as the Fermilab SBN program.

  14. Mujeres en accion: design and baseline data.

    Science.gov (United States)

    Keller, Colleen; Fleury, Julie; Perez, Adriana; Belyea, Michael; Castro, Felipe G

    2011-10-01

    The majority of programs designed to promote physical activity in older Hispanic women includes few innovative theory-based interventions that address cultural relevant strategies. The purpose of this report is to describe the design and baseline data for Mujeres en Accion, a physical activity intervention to increase regular physical activity, and cardiovascular health outcomes among older Hispanic women. Mujeres en Accion [Women in Action for Health], a 12 month randomized controlled trial to evaluate the effectiveness of a social support physical activity intervention in midlife and older Hispanic women. This study tests an innovative intervention, Mujeres en Accion, and includes the use of a theory-driven approach to intervention, explores social support as a theoretical mediating variable, use of a Promotora model and a Community Advisory group to incorporate cultural and social approaches and resources, and use of objective measures of physical activity in Hispanic women. PMID:21298400

  15. The OPERA long baseline neutrino oscillation experiment

    International Nuclear Information System (INIS)

    OPERA is a long baseline neutrino oscillation experiment designed to observe the appearance of vτ in a pure vμ beam in the parameter space indicated by the atmospheric neutrinos oscillation signal. The detector is situated in the underground LNGS laboratory under 3 800 water meter equivalent at a distance of 730 km from CERN where the CNGS neutrino beam to which it is exposed originates. It consists of two identical 0.68 kilotons lead/nuclear emulsion targets, each instrumented with a tracking device and complemented by a muon spectrometer. The concept and the status of the detector are described and the first results obtained with cosmic rays and during two weeks of beam commissioning in 2006 are reported

  16. Digital Offshore Cadastre (DOC) - Pacific83 - Baseline Tangent Lines

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — This data set contains baseline tangent lines and bay closing lines in ESRI Arc/Info export and Arc/View shape file formats for the BOEM Pacific Region. Baseline...

  17. Hypoperfusion in baseline and cognitively activated brain SPECT imaging of adult and elderly patients with depression

    International Nuclear Information System (INIS)

    Objective: To evaluate the rCBF abnormalities of the baseline and cognitively activated rCBF imaging in unmedicated adult and elderly patients with depression. Methods: The subjects were divided into four groups: depressed adults, normal adult controls, depressed elders and normal elderly controls. All depressed patients were unmedicated and the diagnoses (depression of moderate degree with accompanying somatization) were confirmed by the ICD-10 criteria. Age range of the 39 depressed adult patients was 17 - 55 years. 17 age-matched normal adult controls (age range 21 - 50 years) were studied under identical conditions. The age range of 18 depressed elderly patients was 62 - 76 years. 21 age-matched normal elderly controls (age range 60 - 72 years) were studied under identical conditions. Baseline and cognitively activated 99Tcm-ECD SPECT were performed on 25 of the 39 adult patients with depression and 17 normal adult controls. Baseline 99Tcm-ECD SPECT only was performed on the remaining 14 patients with depression. Baseline and cognitively activated 99Tcm-ECD SPECT were performed on 12 of the 18 elderly patients with depression and 18 of the 21 normal elderly controls. Baseline 99Tcm-ECD SPECT only was performed on the remaining elderly patients and 3 normal elderly controls. Results: 1) The characteristic abnormalities of baseline and cognitively activated brain SPECT imaging of depression in adults: the baseline rCBF values of frontal and temporal lobe decreased significantly and the activated rCBF values of frontal, temporal lobe decreased more evidently than that in the baseline imaging and additionally decreased activated rCBF values in parietal lobe were found. 2) The characteristic abnormalities of baseline and cognitively activated brain SPECT imaging of elderly patients with depression: the baseline rCBF values of frontal, temporal lobe and right basal ganglia decreased significantly and the activated rCBF values of frontal, temporal, right parietal lobe

  18. 10 CFR 850.20 - Baseline beryllium inventory.

    Science.gov (United States)

    2010-01-01

    ... 10 Energy 4 2010-01-01 2010-01-01 false Baseline beryllium inventory. 850.20 Section 850.20 Energy... Baseline beryllium inventory. (a) The responsible employer must develop a baseline inventory of the... inventory, the responsible employer must: (1) Review current and historical records; (2) Interview...

  19. An application of the baseline correction technique for correcting distorted seismic acceleration time histories

    International Nuclear Information System (INIS)

    Three kinds of baseline correction techniques named as 'Newmark', 'Zero-VD' and 'Newmark and Zero-VD' were introduced to correct the distorted physical characteristics of a seismic time history accelogram. The corrected seismic accelerations and distorted raw acceleration showed an identical response spectra in frequency domains, but showed various time history profiles in velocity and displacement domains. The referred correction techniques were programmed with UNIX-HP Fortran. The verification of the baseline corrected seismic data in terms of frequency response spectrum were performed by ANSYS of a commerical FEM software

  20. An application of the baseline correction technique for correcting distorted seismic acceleration time histories

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Gyu Mahn; Kim, Jong Wook; Jeoung, Kyeong Hoon; Kim, Tae Wan; Park, Keun Bae; Kim, Keung Koo

    2008-03-15

    Three kinds of baseline correction techniques named as 'Newmark', 'Zero-VD' and 'Newmark and Zero-VD' were introduced to correct the distorted physical characteristics of a seismic time history accelogram. The corrected seismic accelerations and distorted raw acceleration showed an identical response spectra in frequency domains, but showed various time history profiles in velocity and displacement domains. The referred correction techniques were programmed with UNIX-HP Fortran. The verification of the baseline corrected seismic data in terms of frequency response spectrum were performed by ANSYS of a commerical FEM software.

  1. SRS baseline hydrogeologic investigation: Summary report

    Energy Technology Data Exchange (ETDEWEB)

    Bledsoe, H.W.; Aadland, R.K. [Westinghouse Savannah River Co., Aiken, SC (United States); Sargent, K.A. [Furman Univ., Greenville, SC (United States). Dept. of Geology

    1990-11-01

    Work on the Savannah River Site (SRS) Baseline Hydrogeologic Investigation began in 1983 when it was determined that the knowledge of the plant hydrogeologic systems needed to be expanded and improved in response to changing stratigraphic and hydrostratigraphic terminology and increased involvement by regulatory agencies (Bledsoe, 1984). Additionally, site-wide data were needed to determine flow paths, gradients, and velocities associated with the different aquifers underlying the plant site. The program was divided into three phases in order to allow the results of one phase to be evaluated and necessary changes and improvements incorporated into the following phases. This report summarizes the results of all three phases and includes modified graphic logs, lithologic descriptions of the different geologic formations, profiles of each cluster site, hydrostratigraphic cross sections, hydrographs of selected wells within each cluster for the first full year of uninterrupted water level measurements, potentiometric maps developed from data collected from all clusters, completion diagrams for each well, and a summary of laboratory tests. Additionally, the proposed new classification of hydrostratigraphic units at SRS (Aadland and Bledsoe, 1990) has been incorporated.

  2. Accelerated Best Basis Inventory Baselining Task

    International Nuclear Information System (INIS)

    The objectives of the Best Basis Inventory (BBI) baselining effort are to: (1) Provide inventories that are consistent with the revised BBI methodology and new BBI creation rules. (2) Split the total tank waste in each tank into six waste phases, as appropriate (Supernatant, saltcake solids, saltcake liquid, sludge solids, sludge liquid, and retained gas). (3) Identify sampling events that are to be used for calculating the BBIs. (4) Update waste volumes for subsequent reconciliation with the Hanlon (2000) waste tank summary. (5) Implement new waste type templates. (6) Include any sample data that might have been unintentionally omitted in the original BBI and remove any sample data that should not have been included. (7) Sample data to be used in the BBI must be available on TWINS. (8) Ensure that an inventory value is provided for each waste component. Sample based inventories for new supplemental BBI analytes are to be included when available. (9) Provide new means and confidence interval reports if one is not already available and include uncertainties in reporting inventory values

  3. Arc melter demonstration baseline test results

    Energy Technology Data Exchange (ETDEWEB)

    Soelberg, N.R.; Chambers, A.G.; Anderson, G.L.; Oden, L.L.; O`Connor, W.K.; Turner, P.C.

    1994-07-01

    This report describes the test results and evaluation for the Phase 1 (baseline) arc melter vitrification test series conducted for the Buried Waste Integrated Demonstration program (BWID). Phase 1 tests were conducted on surrogate mixtures of as-incinerated wastes and soil. Some buried wastes, soils, and stored wastes at the INEL and other DOE sites, are contaminated with transuranic (TRU) radionuclides and hazardous organics and metals. The high temperature environment in an electric arc furnace may be used to process these wastes to produce materials suitable for final disposal. An electric arc furnace system can treat heterogeneous wastes and contaminated soils by (a) dissolving and retaining TRU elements and selected toxic metals as oxides in the slag phase, (b) destroying organic materials by dissociation, pyrolyzation, and combustion, and (c) capturing separated volatilized metals in the offgas system for further treatment. Structural metals in the waste may be melted and tapped separately for recycle or disposal, or these metals may be oxidized and dissolved into the slag. The molten slag, after cooling, will provide a glass/ceramic final waste form that is homogeneous, highly nonleachable, and extremely durable. These features make this waste form suitable for immobilization of TRU radionuclides and toxic metals for geologic timeframes. Further, the volume of contaminated wastes and soils will be substantially reduced in the process.

  4. Space Station-Baseline Configuration With Callouts

    Science.gov (United States)

    1989-01-01

    In response to President Reagan's directive to NASA to develop a permanent marned Space Station within a decade, part of the State of the Union message to Congress on January 25, 1984, NASA and the Administration adopted a phased approach to Station development. This approach provided an initial capability at reduced costs, to be followed by an enhanced Space Station capability in the future. This illustration depicts the baseline configuration, which features a 110-meter-long horizontal boom with four pressurized modules attached in the middle. Located at each end are four photovoltaic arrays generating a total of 75-kW of power. Two attachment points for external payloads are provided along this boom. The four pressurized modules include the following: A laboratory and habitation module provided by the United States; two additional laboratories, one each provided by the European Space Agency (ESA) and Japan; and an ESA-provided Man-Tended Free Flyer, a pressurized module capable of operations both attached to and separate from the Space Station core. Canada was expected to provide the first increment of a Mobile Serving System.

  5. LTC vacuum blasting machine (concrete): Baseline report

    International Nuclear Information System (INIS)

    The LTC shot blast technology was tested and is being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU's evaluation of efficiency and cost, this report covers the evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The LTC 1073 Vacuum Blasting Machine uses a high-capacity, direct-pressure blasting system which incorporates a continuous feed for the blast media. The blast media cleans the surface within the contained brush area of the blast. It incorporates a vacuum system which removes dust and debris from the surface as it is blasted. The safety and health evaluation during the testing demonstration focused on two main areas of exposure: dust and noise. Dust exposure during maintenance activities was minimal, but due to mechanical difficulties dust monitoring could not be conducted during operation. Noise exposure was significant. Further testing for each of these exposures is recommended because of the outdoor environment where the testing demonstration took place. This may cause the results to be inaccurate. It is feasible that the dust and noise levels will be higher in an enclosed environment. In addition, other safety and health issues found were ergonomics, heat stress, tripping hazards, electrical hazards, lockout/tagout, and arm-hand vibration

  6. Beyond Baselines: Rethinking Priorities for Ocean Conservation

    Directory of Open Access Journals (Sweden)

    Janna M. Shackeroff

    2009-06-01

    Full Text Available In 1995, Daniel Pauly identified a "shifting baselines syndrome" (SBS. Pauly was concerned that scientists measure ecosystem change against their personal recollections of the past and, based on this decidedly short-term view, mismanage fish stocks because they tolerate gradual and incremental elimination of species and set inappropriate recovery goals. As a concept, SBS is simple to grasp and its logic is compelling. Much current work in marine historical ecology is rationalized in part as a means of combating SBS, and the term has also resonated outside of the academy with environmental advocacy groups. Although we recognize both conceptual and operational merit in SBS, we believe that the ultimate impact of SBS on ocean management will be limited by some underlying and interrelated problematic assumptions about ecology and human–environment relations, and the prescriptions that these assumptions support. In this paper, we trace both assumptions and prescriptions through key works in the SBS literature and interrogate them via ecological and social science theory and research. We argue that an expanded discussion of SBS is needed, one that engages a broader range of social scientists, ecologists, and resource users, and that explicitly recognizes the value judgments inherent in deciding both what past ecosystems looked like and whether or not and how we might reconstruct them.

  7. Arc melter demonstration baseline test results

    International Nuclear Information System (INIS)

    This report describes the test results and evaluation for the Phase 1 (baseline) arc melter vitrification test series conducted for the Buried Waste Integrated Demonstration program (BWID). Phase 1 tests were conducted on surrogate mixtures of as-incinerated wastes and soil. Some buried wastes, soils, and stored wastes at the INEL and other DOE sites, are contaminated with transuranic (TRU) radionuclides and hazardous organics and metals. The high temperature environment in an electric arc furnace may be used to process these wastes to produce materials suitable for final disposal. An electric arc furnace system can treat heterogeneous wastes and contaminated soils by (a) dissolving and retaining TRU elements and selected toxic metals as oxides in the slag phase, (b) destroying organic materials by dissociation, pyrolyzation, and combustion, and (c) capturing separated volatilized metals in the offgas system for further treatment. Structural metals in the waste may be melted and tapped separately for recycle or disposal, or these metals may be oxidized and dissolved into the slag. The molten slag, after cooling, will provide a glass/ceramic final waste form that is homogeneous, highly nonleachable, and extremely durable. These features make this waste form suitable for immobilization of TRU radionuclides and toxic metals for geologic timeframes. Further, the volume of contaminated wastes and soils will be substantially reduced in the process

  8. Pentek metal coating removal system: Baseline report

    International Nuclear Information System (INIS)

    The Pentek coating removal technology was tested and is being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU's evaluation of efficiency and cost, this report covers evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The Pentek coating removal system consisted of the ROTO-PEEN Scaler, CORNER-CUTTER reg-sign, and VAC-PAC reg-sign. They are designed to remove coatings from steel, concrete, brick, and wood. The Scaler uses 3M Roto Peen tungsten carbide cutters while the CORNER-CUTTER reg-sign uses solid needles for descaling activities. These hand tools are used with the VAC-PAC reg-sign vacuum system to capture dust and debris as removal of the coating takes place. The safety and health evaluation during the testing demonstration focused on two main areas of exposure: dust and noise. Dust exposure minimal, but noise exposure was significant. Further testing for each exposure is recommended because of the environment where the testing demonstration took place. It is feasible that the dust and noise levels will be higher in an enclosed operating environment of different construction. In addition, other areas of concern found were arm-hand vibration, whole-body, ergonomics, heat stress, tripping hazards, electrical hazards, machine guarding, and lockout/tagout

  9. Integrating risk management into the baselining process

    International Nuclear Information System (INIS)

    These processes work together in building the project (comprised of the technical, schedule, and cost baselines) against which performance is measured and changes to the scope, schedule and cost of a project are managed and controlled. Risk analysis is often performed as the final element of the scheduling or estimating processes, a precursor to establishing cost and schedule contingency. However, best business practices dictate that information that may be crucial to the success of a project be analyzed and incorporated into project planning as soon as it is available and usable. The purpose or risk management is not to eliminate risk. Neither is it intended to suggest wholesale re-estimating and re-scheduling of a project. Rather, the intent is to make provisions to reduce and control the schedule and/or cost ramifications of risk by anticipating events and conditions that cannot be reliably planned for and which have the potential to negatively impact accomplishment of the technical objectives and requirements of the project

  10. Using the Very Long Baseline Array

    Science.gov (United States)

    Wrobel, J. M.

    1999-05-01

    The Very Long Baseline Array (VLBA) is a user facility run by the National Radio Astronomy Observatory (NRAO). Many AAS members currently use the VLBA to study astrophysical topics as diverse as gamma-ray blazars, gravitational lenses, black holes in nearby galaxies, astrometry of pulsars and stellar companions, supernova evolution, magnetic fields in stellar atmospheres, and molecules and atoms in active galaxies. Numerous examples of such studies will be presented at this meeting and many other examples appear in ``Radio Emission from Galactic and Extragalactic Compact Sources'' (1998, ASP Conference Series, Volume 144, eds. J.A. Zensus, G.B. Taylor, and J.M. Wrobel). This talk has three parts. (1) I will briefly summarize the VLBA's capabilities, so potential observers can asses the suitability of the VLBA as a tool for their research and so theorists can become familiar with the parameter space probed with VLBA observations. (2) I will offer guidelines for preparing technically sound proposals to the NRAO for observing time on the VLBA and will describe the proposal process. (3) I will summarize some strategies for VLBA observers to help them optimize the scientific return from their observations, especially when those observations involve phase referencing, polarimetry, surveys, or spectroscopy. The NRAO is a facility of the National Science Foundation operated under cooperative agreement by Associated Universities, Inc.

  11. Lorentz symmetry and Very Long Baseline Interferometry

    CERN Document Server

    Poncin-Lafitte, C Le; lambert, S

    2016-01-01

    Lorentz symmetry violations can be described by an effective field theory framework that contains both General Relativity and the Standard Model of particle physics called the Standard-Model extension (SME). Recently, post-fit analysis of Gravity Probe B and binary pulsars lead to an upper limit at the $10^{-4}$ level on the time-time coefficient $\\bar s^{TT}$ of the pure-gravity sector of the minimal SME. In this work, we derive the observable of Very Long Baseline Interferometry (VLBI) in SME and then we implement it into a real data analysis code of geodetic VLBI observations. Analyzing all available observations recorded since 1979, we compare estimates of $\\bar s^{TT}$ and errors obtained with various analysis schemes, including global estimations over several time spans and with various Sun elongation cut-off angles, and with analysis of radio source coordinate time series. We obtain a constraint on $\\bar s^{TT}=(-5\\pm 8)\\times 10^{-5}$, directly fitted to the observations and improving by a factor 5 pr...

  12. Camera Trajectory fromWide Baseline Images

    Science.gov (United States)

    Havlena, M.; Torii, A.; Pajdla, T.

    2008-09-01

    Camera trajectory estimation, which is closely related to the structure from motion computation, is one of the fundamental tasks in computer vision. Reliable camera trajectory estimation plays an important role in 3D reconstruction, self localization, and object recognition. There are essential issues for a reliable camera trajectory estimation, for instance, choice of the camera and its geometric projection model, camera calibration, image feature detection and description, and robust 3D structure computation. Most of approaches rely on classical perspective cameras because of the simplicity of their projection models and ease of their calibration. However, classical perspective cameras offer only a limited field of view, and thus occlusions and sharp camera turns may cause that consecutive frames look completely different when the baseline becomes longer. This makes the image feature matching very difficult (or impossible) and the camera trajectory estimation fails under such conditions. These problems can be avoided if omnidirectional cameras, e.g. a fish-eye lens convertor, are used. The hardware which we are using in practice is a combination of Nikon FC-E9 mounted via a mechanical adaptor onto a Kyocera Finecam M410R digital camera. Nikon FC-E9 is a megapixel omnidirectional addon convertor with 180° view angle which provides images of photographic quality. Kyocera Finecam M410R delivers 2272×1704 images at 3 frames per second. The resulting combination yields a circular view of diameter 1600 pixels in the image. Since consecutive frames of the omnidirectional camera often share a common region in 3D space, the image feature matching is often feasible. On the other hand, the calibration of these cameras is non-trivial and is crucial for the accuracy of the resulting 3D reconstruction. We calibrate omnidirectional cameras off-line using the state-of-the-art technique and Mičušík's two-parameter model, that links the radius of the image point r to the

  13. The LOFAR long baseline snapshot calibrator survey

    CERN Document Server

    Moldón, J; Wucknitz, O; Jackson, N; Drabent, A; Carozzi, T; Conway, J; Kapińska, A D; McKean, P; Morabito, L; Varenius, E; Zarka, P; Anderson, J; Asgekar, A; Avruch, I M; Bell, M E; Bentum, M J; Bernardi, G; Best, P; Bîrzan, L; Bregman, J; Breitling, F; Broderick, J W; Brüggen, M; Butcher, H R; Carbone, D; Ciardi, B; de Gasperin, F; de Geus, E; Duscha, S; Eislöffel, J; Engels, D; Falcke, H; Fallows, R A; Fender, R; Ferrari, C; Frieswijk, W; Garrett, M A; Grießmeier, J; Gunst, A W; Hamaker, J P; Hassall, T E; Heald, G; Hoeft, M; Juette, E; Karastergiou, A; Kondratiev, V I; Kramer, M; Kuniyoshi, M; Kuper, G; Maat, P; Mann, G; Markoff, S; McFadden, R; McKay-Bukowski, D; Morganti, R; Munk, H; Norden, M J; Offringa, A R; Orru, E; Paas, H; Pandey-Pommier, M; Pizzo, R; Polatidis, A G; Reich, W; Röttgering, H; Rowlinson, A; Scaife, A M M; Schwarz, D; Sluman, J; Smirnov, O; Stappers, B W; Steinmetz, M; Tagger, M; Tang, Y; Tasse, C; Thoudam, S; Toribio, M C; Vermeulen, R; Vocks, C; van Weeren, R J; White, S; Wise, M W; Yatawatta, S; Zensus, A

    2014-01-01

    Aims. An efficient means of locating calibrator sources for International LOFAR is developed and used to determine the average density of usable calibrator sources on the sky for subarcsecond observations at 140 MHz. Methods. We used the multi-beaming capability of LOFAR to conduct a fast and computationally inexpensive survey with the full International LOFAR array. Sources were pre-selected on the basis of 325 MHz arcminute-scale flux density using existing catalogues. By observing 30 different sources in each of the 12 sets of pointings per hour, we were able to inspect 630 sources in two hours to determine if they possess a sufficiently bright compact component to be usable as LOFAR delay calibrators. Results. Over 40% of the observed sources are detected on multiple baselines between international stations and 86 are classified as satisfactory calibrators. We show that a flat low-frequency spectrum (from 74 to 325 MHz) is the best predictor of compactness at 140 MHz. We extrapolate from our sample to sho...

  14. The LBNO long-baseline oscillation sensitivities with two conventional neutrino beams at different baselines

    CERN Document Server

    :,; Agostino, L; Aittola, M; Alekou, A; Andrieu, B; Antoniou, F; Asfandiyarov, R; Autiero, D; Bésida, O; Balik, A; Ballett, P; Bandac, I; Banerjee, D; Bartmann, W; Bay, F; Biskup, B; Blebea-Apostu, A M; Blondel, A; Bogomilov, M; Bolognesi, S; Borriello, E; Brancus, I; Bravar, A; Buizza-Avanzini, M; Caiulo, D; Calin, M; Calviani, M; Campanelli, M; Cantini, C; Cata-Danil, G; Chakraborty, S; Charitonidis, N; Chaussard, L; Chesneanu, D; Chipesiu, F; Crivelli, P; Dawson, J; De Bonis, I; Declais, Y; Sanchez, P Del Amo; Delbart, A; Di Luise, S; Duchesneau, D; Dumarchez, J; Efthymiopoulos, I; Eliseev, A; Emery, S; Enqvist, T; Enqvist, K; Epprecht, L; Erykalov, A N; Esanu, T; Franco, D; Friend, M; Galymov, V; Gavrilov, G; Gendotti, A; Giganti, C; Gilardoni, S; Goddard, B; Gomoiu, C M; Gornushkin, Y A; Gorodetzky, P; Haesler, A; Hasegawa, T; Horikawa, S; Huitu, K; Izmaylov, A; Jipa, A; Kainulainen, K; Karadzhov, Y; Khabibullin, M; Khotjantsev, A; Kopylov, A N; Korzenev, A; Kosyanenko, S; Kryn, D; Kudenko, Y; Kuusiniemi, P; Lazanu, I; Lazaridis, C; Levy, J -M; Loo, K; Maalampi, J; Margineanu, R M; Marteau, J; Martin-Mari, C; Matveev, V; Mazzucato, E; Mefodiev, A; Mineev, O; Mirizzi, A; Mitrica, B; Murphy, S; Nakadaira, T; Narita, S; Nesterenko, D A; Nguyen, K; Nikolics, K; Noah, E; Novikov, Yu; Oprima, A; Osborne, J; Ovsyannikova, T; Papaphilippou, Y; Pascoli, S; Patzak, T; Pectu, M; Pennacchio, E; Periale, L; Pessard, H; Popov, B; Ravonel, M; Rayner, M; Resnati, F; Ristea, O; Robert, A; Rubbia, A; Rummukainen, K; Saftoiu, A; Sakashita, K; Sanchez-Galan, F; Sarkamo, J; Saviano, N; Scantamburlo, E; Sergiampietri, F; Sgalaberna, D; Shaposhnikova, E; Slupecki, M; Smargianaki, D; Stanca, D; Steerenberg, R; Sterian, A R; Sterian, P; Stoica, S; Strabel, C; Suhonen, J; Suvorov, V; Toma, G; Tonazzo, A; Trzaska, W H; Tsenov, R; Tuominen, K; Valram, M; Vankova-Kirilova, G; Vannucci, F; Vasseur, G; Velotti, F; Velten, P; Venturi, V; Viant, T; Vihonen, S; Vincke, H; Vorobyev, A; Weber, A; Wu, S; Yershov, N; Zambelli, L; Zito, M

    2014-01-01

    The proposed Long Baseline Neutrino Observatory (LBNO) initially consists of $\\sim 20$ kton liquid double phase TPC complemented by a magnetised iron calorimeter, to be installed at the Pyh\\"asalmi mine, at a distance of 2300 km from CERN. The conventional neutrino beam is produced by 400 GeV protons accelerated at the SPS accelerator delivering 700 kW of power. The long baseline provides a unique opportunity to study neutrino flavour oscillations over their 1st and 2nd oscillation maxima exploring the $L/E$ behaviour, and distinguishing effects arising from $\\delta_{CP}$ and matter. In this paper we show how this comprehensive physics case can be further enhanced and complemented if a neutrino beam produced at the Protvino IHEP accelerator complex, at a distance of 1160 km, and with modest power of 450 kW is aimed towards the same far detectors. We show that the coupling of two independent sub-MW conventional neutrino and antineutrino beams at different baselines from CERN and Protvino will allow to measure ...

  15. Nonintrusive methodology for wellness baseline profiling

    Science.gov (United States)

    Chung, Danny Wen-Yaw; Tsai, Yuh-Show; Miaou, Shaou-Gang; Chang, Walter H.; Chang, Yaw-Jen; Chen, Shia-Chung; Hong, Y. Y.; Chyang, C. S.; Chang, Quan-Shong; Hsu, Hon-Yen; Hsu, James; Yao, Wei-Cheng; Hsu, Ming-Sin; Chen, Ming-Chung; Lee, Shi-Chen; Hsu, Charles; Miao, Lidan; Byrd, Kenny; Chouikha, Mohamed F.; Gu, Xin-Bin; Wang, Paul C.; Szu, Harold

    2007-04-01

    We develop an accumulatively effective and affordable set of smart pair devices to save the exuberant expenditure for the healthcare of aging population, which will not be sustainable when all the post-war baby boomers retire (78 millions will cost 1/5~1/4 GDP in US alone). To design an accessible test-bed for distributed points of homecare, we choose two exemplars of the set to demonstrate the possibility of translation of modern military and clinical know-how, because two exemplars share identically the noninvasive algorithm adapted to the Smart Sensor-pairs for the real world persistent surveillance. Currently, the standard diagnoses for malignant tumors and diabetes disorders are blood serum tests, X-ray CAT scan, and biopsy used sometime in the physical checkup by physicians as cohort-average wellness baselines. The loss of the quality of life in making second careers productive may be caused by the missing of timeliness for correct diagnoses and easier treatments, which contributes to the one quarter of human errors generating the lawsuits against physicians and hospitals, which further escalates the insurance cost and wasteful healthcare expenditure. Such a vicious cycle should be entirely eliminated by building an "individual diagnostic aids (IDA)," similar to the trend of personalized drug, developed from daily noninvasive intelligent databases of the "wellness baseline profiling (WBP)". Since our physiology state undulates diurnally, the Nyquist anti-aliasing theory dictates a minimum twice-a-day sampling of the WBP for the IDA, which must be made affordable by means of noninvasive, unsupervised and unbiased methodology at the convenience of homes. Thus, a pair of military infrared (IR) spectral cameras has been demonstrated for the noninvasive spectrogram ratio test of the spontaneously emitted thermal radiation from a normal human body at 37°C temperature. This invisible self-emission spreads from 3 microns to 12 microns of the radiation wavelengths

  16. 100-D Area technical baseline report

    Energy Technology Data Exchange (ETDEWEB)

    Carpenter, R.W.

    1993-08-20

    This document is prepared in support of the 100 Area Environmental Restoration activity at the US Department of Energy`s Hanford Site near Richland, Washington. It provides a technical baseline of waste sites located at the 100-D Area. The report is based on an environmental investigation undertaken by the Westinghouse Hanford Company (WHC) History Office in support of the Environmental Restoration Engineering Function and on review and evaluation of numerous Hanford Site current and historical reports, drawings, and photographs, supplemented by site inspections and employee interviews. No intrusive field investigation or sampling was conducted. All Hanford coordinate locations are approximate locations taken from several different maps and drawings of the 100-D Area. Every effort was made to derive coordinate locations for the center of each facility or waste site, except where noted, using standard measuring devices. Units of measure are shown as they appear in reference documents. The 100-D Area is made up of three operable units: 100-DR-1, 100-DR-2, and 100-DR-3. All three are addressed in this report. These operable units include liquid and solid waste disposal sites in the vicinity of, and related to, the 100-D and 100-DR Reactors. A fourth operable unit, 100-HR-3, is concerned with groundwater and is not addressed here. This report describes waste sites which include cribs, trenches, pits, french drains, retention basins, solid waste burial grounds, septic tanks, and drain fields. Each waste site is described separately and photographs are provided where available. A complete list of photographs can be found in Appendix A. A comprehensive environmental summary is not provided here but may be found in Hanford Site National Environmental Policy Act Characterization (Cushing 1988), which describes the geology and soils, meteorology, hydrology, land use, population, and air quality of the area.

  17. 100-D Area technical baseline report

    International Nuclear Information System (INIS)

    This document is prepared in support of the 100 Area Environmental Restoration activity at the US Department of Energy's Hanford Site near Richland, Washington. It provides a technical baseline of waste sites located at the 100-D Area. The report is based on an environmental investigation undertaken by the Westinghouse Hanford Company (WHC) History Office in support of the Environmental Restoration Engineering Function and on review and evaluation of numerous Hanford Site current and historical reports, drawings, and photographs, supplemented by site inspections and employee interviews. No intrusive field investigation or sampling was conducted. All Hanford coordinate locations are approximate locations taken from several different maps and drawings of the 100-D Area. Every effort was made to derive coordinate locations for the center of each facility or waste site, except where noted, using standard measuring devices. Units of measure are shown as they appear in reference documents. The 100-D Area is made up of three operable units: 100-DR-1, 100-DR-2, and 100-DR-3. All three are addressed in this report. These operable units include liquid and solid waste disposal sites in the vicinity of, and related to, the 100-D and 100-DR Reactors. A fourth operable unit, 100-HR-3, is concerned with groundwater and is not addressed here. This report describes waste sites which include cribs, trenches, pits, french drains, retention basins, solid waste burial grounds, septic tanks, and drain fields. Each waste site is described separately and photographs are provided where available. A complete list of photographs can be found in Appendix A. A comprehensive environmental summary is not provided here but may be found in Hanford Site National Environmental Policy Act Characterization (Cushing 1988), which describes the geology and soils, meteorology, hydrology, land use, population, and air quality of the area

  18. [The study of baseline estimated in digital XRF analyzer].

    Science.gov (United States)

    Wang, Min; Zhou, Jian-Bin; Fang, Fang; Shi, Ze-Ming; Zhou, Wei; Liu, Yi; Cao, Jian-Yu; Zhu, Xing

    2013-01-01

    For the digital X-ray fluorescence analyzer, the voltage of the instability baseline will directly affect the performance of the instrument, resulting in decreased energy resolution. In order to solve this problem, Kalman filtering algorithm was used for pulse signal baseline estimate in the digital X-ray fluorescence. Whether using the classic Kalman filter, or the simplified sage-husa, or the improved sage-husa, their baseline filtering effects were all poor. So, it is necessary to improve and optimize existing algorithms. The method of Double-Forgotten was put forward to establish a new model of adaptive Kalman filter algorithm based on the sage-husa. The experiment results show that a very good filtering effect was obtained using the mathematical model of the baseline filter. The algorithm solved the problem of filtering divergence, avoided slow convergence of baseline and realized the pulse baseline restoration, and improved the instrumental energy resolution. PMID:23586263

  19. Absolute Baseline for Testing of Electronic Distance Meters

    OpenAIRE

    Jaroslav Braun; Filip Dvořáček; Martin Štroner

    2014-01-01

    The paper deals with the construction and determination of coordinates of the absoluteEDMs baseline in a laboratory with 16 pillars with forced centring. Leica Absolute TrackerAT401 (standard deviation of distance measurement: 5 μ m, standard deviation of anglemeasurement: 0.15 mgon), which is designed for very accurate industrial measurements,was used for our purpose. Lengths between the baseline points were determined with astandard deviation of 0.02 mm. The baseline is used for determining...

  20. Spent Nuclear Fuel Project technical baseline document. Fiscal year 1995: Volume 1, Baseline description

    International Nuclear Information System (INIS)

    This document is a revision to WHC-SD-SNF-SD-002, and is issued to support the individual projects that make up the Spent Nuclear Fuel Project in the lower-tier functions, requirements, interfaces, and technical baseline items. It presents results of engineering analyses since Sept. 1994. The mission of the SNFP on the Hanford site is to provide safety, economic, environmentally sound management of Hanford SNF in a manner that stages it to final disposition. This particularly involves K Basin fuel, although other SNF is involved also

  1. Economic Needs of Asian Americans and Pacific Islanders in Distressed Areas: Establishing Baseline Information

    OpenAIRE

    Ong, Paul M.; Miller, Douglas

    2002-01-01

    This report provides baseline statistics needed for policy-oriented research on disadvantaged Asian-Pacific Americans (APAs) neighborhoods. We profile 17 poor APA neighborhoods across the United States and provide insights from a survey of community-based organizations (CBOs). The neighborhood profiles reveal diverse neighborhood characteristics, including variations in economic base, size, and ethnic composition. In spite of substantial differences, some common features are seen. Most neighb...

  2. Economic Needs of Asian Americans and Pacific Islanders in Distressed Areas: Establishing Baseline Information

    OpenAIRE

    Ong, Paul M.; Miller, Douglas

    2002-01-01

    This report provides baseline statistics needed for policy-oriented research on disadvantaged Asian-Pacific Americans (APAs) neighborhoods. We profile 17 poor APA neighborhoods across the United States and provide insights from a survey of community-based organizations (CBOs). The neighborhood profiles reveal diverse neighborhood characteristics, including variations in economic base, size, and ethnic composition. In spite of substantial differences, some common features are seen. Most nei...

  3. The Emergy Baseline of the Earth: Is it Arbitrary?

    Science.gov (United States)

    The emergy baseline for the Earth is used in determining the transformities of the products of all planetary processes and through these relationships it influences all emergy evaluations. Estimates of the emergy baseline made in the past have changed depending on the number of i...

  4. Searching for neutrino oscillation parameters in long baseline experiments

    CERN Document Server

    Vihonen, Sampsa

    2016-01-01

    Developing neutrino astronomy requires a good understanding of the neutrino oscillations mechanism. The European strategy for neutrino oscillation physics sets a high priority on future long baseline neutrino experiments with the aim to measure the intrinsic parameters that govern the neutrino oscillations. In this work we take a look at the next generation of long baseline experiments and discuss their prospects in future research.

  5. Digital Offshore Cadastre (DOC) - Pacific83 - Baseline Points

    Data.gov (United States)

    Bureau of Ocean Energy Management, Department of the Interior — This data set contains baseline points in ESRI Arc/Info export and Arc/View shape file formats for the BOEM Pacific Region. Baseline points are used by the BOEM to...

  6. 40 CFR 80.92 - Baseline auditor requirements.

    Science.gov (United States)

    2010-07-01

    ...) Independence. The auditor, its contractors, subcontractors and their organizations shall be independent of the... 40 Protection of Environment 16 2010-07-01 2010-07-01 false Baseline auditor requirements. 80.92... (CONTINUED) REGULATION OF FUELS AND FUEL ADDITIVES Anti-Dumping § 80.92 Baseline auditor requirements....

  7. Esophageal impedance baseline according to different time intervals

    Directory of Open Access Journals (Sweden)

    Ummarino Dario

    2012-06-01

    Full Text Available Abstract Background The impedance baseline has been shown to reflect esophageal integrity, and to be decreased in patients with esophagitis. However, different methods for the determination of the impedance baseline have not been compared. Methods The median impedance baseline was calculated in 10 consecutive multichannel intraluminal impedance recordings in children with non-erosive reflux disease. All children underwent an endoscopy with a biopsy as part of the clinical work-up to exclude esophagitis. The impedance baseline was obtained both by including and excluding all impedance episodes (IE; reflux, swallows and gas episodes during the full recording, and during the first 1-minute period without an IE every hour (method 1, every 2 hours (method 2 or every 4 hours (method 3. The impedance baseline obtained during the full recording was set at 100%, and the variation (difference in impedance baseline for the different methods and variability (difference in impedance baseline during one analysis period were assessed. Results None of the participants had esophagitis. The mean difference over the six channels between the impedance baseline over the total recording with and without IE was approximately 2.5%, and comparable for each channel (range 0.47% to 5.55%. A mean of 1,028 IEs were excluded in each tracing, and it took between 4 and 24 hours to delete all events in one tracing. The difference in the impedance baseline obtained with and without IEs was mainly caused by the gas episodes in the upper channels and swallows in the lower channels. The median impedance baseline according to the three one-minute analysis methods was comparable to the median impedance baseline according to the 24 hour analysis. Conclusions The automatic determination of the median impedance baseline over the total tracing including IEs is an adequate method. In isolated tracings with numerous IEs, the calculation of the median impedance baseline over one minute

  8. Site Outcomes Baseline Multi Year Work Plan Volume 1, River Corridor Restoration Baseline

    International Nuclear Information System (INIS)

    The River Corridor Restoration volume is a compilation of Hanford Site scope, which excludes the approximately 194 km2 Central Plateau. The River Corridor scope is currently contractually assigned to Fluor Hanford, Bechtel Hanford, inc., DynCorp, and Pacific Northwest National Laboratory, and others. The purpose of this project specification is to provide an overall scoping document for the River Corridor Restoration volume, and to provide a link with the overall Hanford Site River Corridor scope. Additionally, this specification provides an integrated and consolidated source of information for the various scopes, by current contract, for the River Corridor Restoration Baseline. It identifies the vision, mission, and goals, as well as the operational history of the Hanford Site, along with environmental setting and hazards

  9. Baseline suppression of vehicle portal monitor gamma count profiles: A characterization study

    International Nuclear Information System (INIS)

    Radiation portal monitor (RPM) systems based upon polyvinyl toluene scintillator (PVT) gamma-ray detectors have been deployed to detect illicit trafficking in radioactive materials at border crossings. This report sets forth a characterization of the baseline suppression effect in gross-count gamma-ray profiles due to shadow shielding by vehicles entering RPMs. Shadow shielding is of interest because it reduces the alarm sensitivity of RPMs. This observational study investigated three types of PVT-based commercial RPM systems currently deployed at selected ports of entry in terms of spatial effects relative to detector panel positioning. Radiation portal monitor sites were characterized by driver versus passenger side, top versus bottom panel, and narrow lanes versus wide lanes as observed for a large number of vehicles. Each portal site appears to have a distinctive baseline suppression signature, based on percent maximum suppression relative to measured background. Results suggest that alarm algorithms based on gross-counts may be further refined through attention to individual site characteristics. In addition, longer vehicle transit times were often correlated with stronger baseline suppression, suggesting that baseline suppression studies should take transit time into account

  10. Personality characteristics and sleep variables.

    Science.gov (United States)

    Nakazawa, Y; Kotorii, M; Arikawa, K; Horikawa, S; Hasuzawa, H

    1975-01-01

    In a sleep study of 14 normal healthy adults an investigation was made of sleep measurements of a baseline record for its eventual relationship to the percentage of increase of REM percentage of the 1st recovery night following partial differential REM deprivation (PDRD), as well as to personality characteristics. The percentage of change in NREM sleep of the 1st recovery night was compared with the baseline record andthen compared with corresponding values of REM sleep. The results are summarized as follows. No significant correlation exists between the percentage of increase in the REM percentage of the 1st recovery night and sleep measures of the baseline record. An investigation of the relationship between sleep measures of the baseline record and personality characteristics revealed that stage SWS(%) was significantly greater in the introvert than in the extrovert, in the neurotic than in the non-neurotic, and in the nervous than in the optimistic. Comparison of the changes in NREM and REM sleep percentages of the 1st recovery night with the baseline record was made between paired personality characteristics. A significantly high percentage of increase in REM percentage was almost always associated with a significantly high percentage of decrease in stage 2 percentage. From these results it was inferred that an increase in REM percentage occurs at the expense of stage 2 percentage. PMID:170175

  11. Griffiss AFB integrated resource assessment. Volume 2, Electric baseline detail

    Energy Technology Data Exchange (ETDEWEB)

    Dixon, D.R.; Armstrong, P.R.; Keller, J.M.

    1993-02-01

    The US Air Force Air Combat Command has tasked the Pacific Northwest Laboratory (PNL) as the lead laboratory supporting the US Department of Energy (DOE) Federal Energy Management Program`s (FEMP) mission to identify, evaluate, and assist in acquiring all cost-effective energy projects at Griffiss Air Force Base (AFB). This is a model program PNL is designing for federal customers served by the Niagara Mohawk Power Company (Niagara Mohawk). It will (1) identify and evaluate all electric cost-effective energy projects; (2) develop a schedule at each installation for project acquisition considering project type, size, timing, and capital requirements, as well as energy and dollar savings; and (3) secure 100% of the financing required to implement electric energy efficiency projects from Niagara Mohawk and have Niagara Mohawk procure the necessary contractors to perform detailed audits and install the technologies. This report documents the assessment of baseline energy use at one of Niagara Mohawk`s primary federal facilities, Griffiss AFB, an Air Combat Command facility located near Rome, New York. It is a companion report to Volume 1, the Executive Summary, and Volume 3, the Electric Resource Assessment. The analysis examines the characteristics of electric, gas, oil, propane, coal, and purchased thermal capacity use for fiscal year (FY) 1990. The results include energy-use intensities for the facilities at Griffiss AFB by building type and electric energy end use. A complete electric energy consumption reconciliation is presented that accounts for the distribution of all major electric energy uses and losses among buildings, utilities, and central systems.

  12. A Wavelet Packets Approach to Electrocardiograph Baseline Drift Cancellation

    Directory of Open Access Journals (Sweden)

    Mohammad Ali Tinati

    2006-01-01

    Full Text Available Baseline wander elimination is considered a classical problem. In electrocardiography (ECG signals, baseline drift can influence the accurate diagnosis of heart disease such as ischemia and arrhythmia. We present a wavelet-transform- (WT- based search algorithm using the energy of the signal in different scales to isolate baseline wander from the ECG signal. The algorithm computes wavelet packet coefficients and then in each scale the energy of the signal is calculated. Comparison is made and the branch of the wavelet binary tree corresponding to higher energy wavelet spaces is chosen. This algorithm is tested using the data record from MIT/BIH database and excellent results are obtained.

  13. Parametric estimation of time varying baselines in airborne interferometric SAR

    DEFF Research Database (Denmark)

    Mohr, Johan Jacob; Madsen, Søren Nørvang

    1996-01-01

    A method for estimation of time varying spatial baselines in airborne interferometric synthetic aperture radar (SAR) is described. The range and azimuth distortions between two images acquired with a non-linear baseline are derived. A parametric model of the baseline is then, in a least square...... sense, estimated from image shifts obtained by cross correlation of numerous small patches throughout the image. The method has been applied to airborne EMISAR imagery from the 1995 campaign over the Storstrommen Glacier in North East Greenland conducted by the Danish Center for Remote Sensing. This has...

  14. Trinocular Stereo Matching Based on Correlations Between Baselines and Disparities

    Institute of Scientific and Technical Information of China (English)

    GUANYepeng; GUWeikang

    2004-01-01

    Gray correlation technique is utilized to take the multi-peak feature points with gray correlation coefficients less than a certain range of maximal correlation coefficient as a potential candidate matching set. There exists the maximal correlation between the correct disparities and their corresponding baselines. A trinocular stereo matching algorithm is proposed based on correlations between the baselines and disparities. After computing the correlations between the baselines and disparities, the unique matches can be determined by maximal correlation coefficient. It is proved that the algorithm proposed is valid and credible by 3-D reconstruction on two pairs of actual natural stereo images.

  15. Absolute Baseline for Testing of Electronic Distance Meters

    Directory of Open Access Journals (Sweden)

    Jaroslav Braun

    2014-06-01

    Full Text Available The paper deals with the construction and determination of coordinates of the absoluteEDMs baseline in a laboratory with 16 pillars with forced centring. Leica Absolute TrackerAT401 (standard deviation of distance measurement: 5 μ m, standard deviation of anglemeasurement: 0.15 mgon, which is designed for very accurate industrial measurements,was used for our purpose. Lengths between the baseline points were determined with astandard deviation of 0.02 mm. The baseline is used for determining systematic and randomerrors of distance meters and for accuracy of distance meters at short distances commonin engineering surveying for purposes of mechanical engineering.

  16. Neutrino-factory storage ring with multiple baselines

    CERN Document Server

    Cline, David B; Garren, A

    2001-01-01

    We designed a noble bow tie storage ring to provide neutrino beams for multiple neutrino detectors around the world with a baseline length of about 1000-9000 km. We present a preliminary lattice that could provide non-planar straight sections. We describe the amount of non-planarity of the third or fourth baseline and the space angles between the baselines and the local surface angles at possible site locations for neutrino factories and at the possible detector locations. We describe the detectors at the Gran Sasso Laboratory, Italy, and at the new laboratory at Carlsbad, NM.

  17. Information architecture. Volume 2, Part 1: Baseline analysis summary

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1996-12-01

    The Department of Energy (DOE) Information Architecture, Volume 2, Baseline Analysis, is a collaborative and logical next-step effort in the processes required to produce a Departmentwide information architecture. The baseline analysis serves a diverse audience of program management and technical personnel and provides an organized way to examine the Department`s existing or de facto information architecture. A companion document to Volume 1, The Foundations, it furnishes the rationale for establishing a Departmentwide information architecture. This volume, consisting of the Baseline Analysis Summary (part 1), Baseline Analysis (part 2), and Reference Data (part 3), is of interest to readers who wish to understand how the Department`s current information architecture technologies are employed. The analysis identifies how and where current technologies support business areas, programs, sites, and corporate systems.

  18. Butler Hollow Glades : Baseline assessment and vegetation monitoring establishment

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Several sampling and documentation protocols were implemented to establish baseline vegetation data. These data will provide a comparison point for future...

  19. Baseline Bone Mineral Density Measurements Key to Future Testing Intervals

    Science.gov (United States)

    ... historical) Baseline Bone Mineral Density Measurements Key to Future Testing Intervals How often a woman should have ... BMD tests of the hip using a standard technology called dual-energy x-ray absorptiometry, or DXA. ...

  20. Baseline inventory data users guide to abiotic GIS layers

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — The Baseline Inventory Team was chartered by the Fulfilling the Promises Implementation Team to recommend minimum abiotic and biotic inventories for the National...

  1. Effects of baseline risk information on social and individual choices.

    Science.gov (United States)

    Gyrd-Hansen, Dorte; Kristiansen, Ivar Sønbø; Nexøe, Jørgen; Nielsen, Jesper Bo

    2002-01-01

    This article analyzes preferences for risk reductions in the context of individual and societal decision making. The effect of information on baseline risk is analyzed in both contexts. The results indicate that if individuals are to imagine that they suffer from 1 low-risk and 1 high-risk ailment, and are offered a specified identical absolute risk reduction, a majority will ceteris paribus opt for treatment of the low-risk ailment. A different preference structure is elicited when priority questions are framed as social choices. Here, a majority will prefer to treat the high-risk group of patients. The preference reversal demonstrates the extent to which baseline risk information can influence preferences in different choice settings. It is argued that presentation of baseline risk information may induce framing effects that lead to nonoptimal resource allocations. A solution to this problem may be to not present group-specific baseline risk information when eliciting preferences. PMID:11833667

  2. Environmental Measurements Laboratory. Regional Baseline Station, Chester, New Jersey

    International Nuclear Information System (INIS)

    Research programs conducted at the Regional Baseline Station at Chester, NJ during 1981 are reported. Data are presented on chemical air pollutants and background radiation. Items within the scope of EDB have been entered individually into the data base

  3. Baseline assessment of fish communities of the Flower Garden Banks

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The work developed baseline information on fish and benthic communities within the Flower Garden Banks National Marine Sanctuary (FGBNMS). Surveys employed diving,...

  4. GPS baseline configuration design based on robustness analysis

    Science.gov (United States)

    Yetkin, M.; Berber, M.

    2012-11-01

    The robustness analysis results obtained from a Global Positioning System (GPS) network are dramatically influenced by the configurationof the observed baselines. The selection of optimal GPS baselines may allow for a cost effective survey campaign and a sufficiently robustnetwork. Furthermore, using the approach described in this paper, the required number of sessions, the baselines to be observed, and thesignificance levels for statistical testing and robustness analysis can be determined even before the GPS campaign starts. In this study, wepropose a robustness criterion for the optimal design of geodetic networks, and present a very simple and efficient algorithm based on thiscriterion for the selection of optimal GPS baselines. We also show the relationship between the number of sessions and the non-centralityparameter. Finally, a numerical example is given to verify the efficacy of the proposed approach.

  5. Deriving CGE Baselines from Macro-economic Projections

    OpenAIRE

    Mueller, Marc; FERRARI Emanuele

    2011-01-01

    Quantitative policy analysts are usually confronted with the problem to derive a base-line scenario that reflects the most likely state of an economy in a future year. The methods used in practice to derive such a base-line scenarios are heterogeneous and range from the usage of the last observable year to complete and consistent estimation procedures. In the case of general equilibrium (CGE) analyses, the Scenar2020 project (European Commission 2006a) is one example how projections of macro-...

  6. Fusion of a Variable Baseline System and a Range Finder

    OpenAIRE

    Rafael Arnay; Javier Hernández-Aceituno; Leopoldo Acosta

    2011-01-01

    One of the greatest difficulties in stereo vision is the appearance of ambiguities when matching similar points from different images. In this article we analyze the effectiveness of using a fusion of multiple baselines and a range finder from a theoretical point of view, focusing on the results of using both prismatic and rotational articulations for baseline generation, and offer a practical case to prove its efficiency on an autonomous vehicle.

  7. Uncertainty in Clean Development Mechanism Baselines: Sources, Ramifications, and Negotiations

    OpenAIRE

    Bushey, Douglas

    2005-01-01

    Awarding Certified Emission Reductions to Clean Development Mechanism (CDM) projects under the Kyoto Protocol involves comparing the actual emissions of the project to a counterfactual “baseline” emissions level. The baseline of a project is intended to represent the emissions that would have occurred in the absence of the project. Accordingly, there is a high degree of uncertainty in determining CDM baselines. In the years since the emergence of the CDM, scientific and political debates h...

  8. Baseline implementations of the Standard Line Editor (SLED)

    OpenAIRE

    Taylor, C F; Burnham, R.; Coulter, R.; Smart, S.; Cox, Lyle Ashton

    1980-01-01

    In response to a recognized requirement for a more uniform man machine interface, especially in multiple machine networks, a standardized text editor was proposed (1). This editor, "SLED" was designed to be easily implementable in several commonly available higher level languages. This document reviews two baseline implementations taken directly from the SLED standards which users may want to consider when implementing SLED upon local systems. These baseline programs were written and...

  9. CMB Experiment Baseline Determination by Minimizing Pixel Observations Dispersion

    OpenAIRE

    Smoot, George F.

    1997-01-01

    This paper discusses a couple of approaches to removing instrument gain and baseline variation from observations of the CMB anisotropy. These techniques were tested on the COBE DMR data, a balloon experiment, and by monte carlo simulations. This work, though considered technical, is made available because CMB anisotropy mapping data processing is currently very active and a significant number of groups are working on this issue. Specifically, time-ordered estimates of the gain and baseline vi...

  10. A Review of Long-baseline Neutrino Oscillation Experiments

    OpenAIRE

    Feldman, G J; Hartnell, J.; T. Kobayashi

    2012-01-01

    A review of accelerator long-baseline neutrino oscillation experiments is provided, including all experiments performed to date and the projected sensitivity of those currently in progress. Accelerator experiments have played a crucial role in the confirmation of the neutrino oscillation phenomenon and in precision measurements of the parameters. With a fixed baseline and detectors providing good energy resolution, precise measurements of the ratio of distance/energy (L/E) on the scale of ind...

  11. Urinary neurotransmitter testing: considerations of spot baseline norepinephrine and epinephrine

    OpenAIRE

    Hinz, Marty; Stein, Alvin; Uncini,Tom

    2011-01-01

    Marty Hinz1 Alvin Stein2 Thomas Uncini31Clinical Research, NeuroResearch Clinics Inc., Cape Coral, FL, USA; 2Stein Orthopedic Associates, Plantation, FL, USA; 3DBS Laboratories, Duluth, MN, USABackground: The purpose of this paper is to present the results of statistical analysis of spot baseline urinary norepinephrine and epinephrine assays in correlation with spot baseline urinary serotonin and dopamine findings previously published by the authors. Our research indicates a need for physicia...

  12. Fusion of a variable baseline system and a range finder.

    Science.gov (United States)

    Hernández-Aceituno, Javier; Acosta, Leopoldo; Arnay, Rafael

    2012-01-01

    One of the greatest difficulties in stereo vision is the appearance of ambiguities when matching similar points from different images. In this article we analyze the effectiveness of using a fusion of multiple baselines and a range finder from a theoretical point of view, focusing on the results of using both prismatic and rotational articulations for baseline generation, and offer a practical case to prove its efficiency on an autonomous vehicle. PMID:22368469

  13. Fusion of a Variable Baseline System and a Range Finder

    Directory of Open Access Journals (Sweden)

    Rafael Arnay

    2011-12-01

    Full Text Available One of the greatest difficulties in stereo vision is the appearance of ambiguities when matching similar points from different images. In this article we analyze the effectiveness of using a fusion of multiple baselines and a range finder from a theoretical point of view, focusing on the results of using both prismatic and rotational articulations for baseline generation, and offer a practical case to prove its efficiency on an autonomous vehicle.

  14. CDM Baseline Construction for Vietnam National Electricity Grid

    OpenAIRE

    Tuyen, Tran Minh; Michaelowa, Axel

    2004-01-01

    For projects under the Clean Development Mechanism (CDM), a baseline has to be set to allow calculation of the greenhouse gas emissions reductions achieved. An important obstacle to CDM project development is the lack of data for baseline definition; often project developers do not have access to data and therefore incur high transaction costs to collect them. The government of Vietnam has set up all necessary institutions for CDM, wants to promote CDM projects and thus is interested to reduc...

  15. MALDI-TOF Baseline Drift Removal Using Stochastic Bernstein Approximation

    Directory of Open Access Journals (Sweden)

    Howard Daniel

    2006-01-01

    Full Text Available Stochastic Bernstein (SB approximation can tackle the problem of baseline drift correction of instrumentation data. This is demonstrated for spectral data: matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF data. Two SB schemes for removing the baseline drift are presented: iterative and direct. Following an explanation of the origin of the MALDI-TOF baseline drift that sheds light on the inherent difficulty of its removal by chemical means, SB baseline drift removal is illustrated for both proteomics and genomics MALDI-TOF data sets. SB is an elegant signal processing method to obtain a numerically straightforward baseline shift removal method as it includes a free parameter that can be optimized for different baseline drift removal applications. Therefore, research that determines putative biomarkers from the spectral data might benefit from a sensitivity analysis to the underlying spectral measurement that is made possible by varying the SB free parameter. This can be manually tuned (for constant or tuned with evolutionary computation (for .

  16. An automated baseline correction protocol for infrared spectra of atmospheric aerosols collected on polytetrafluoroethylene (Teflon) filters

    Science.gov (United States)

    Kuzmiakova, Adele; Dillner, Ann M.; Takahama, Satoshi

    2016-06-01

    A growing body of research on statistical applications for characterization of atmospheric aerosol Fourier transform infrared (FT-IR) samples collected on polytetrafluoroethylene (PTFE) filters (e.g., Russell et al., 2011; Ruthenburg et al., 2014) and a rising interest in analyzing FT-IR samples collected by air quality monitoring networks call for an automated PTFE baseline correction solution. The existing polynomial technique (Takahama et al., 2013) is not scalable to a project with a large number of aerosol samples because it contains many parameters and requires expert intervention. Therefore, the question of how to develop an automated method for baseline correcting hundreds to thousands of ambient aerosol spectra given the variability in both environmental mixture composition and PTFE baselines remains. This study approaches the question by detailing the statistical protocol, which allows for the precise definition of analyte and background subregions, applies nonparametric smoothing splines to reproduce sample-specific PTFE variations, and integrates performance metrics from atmospheric aerosol and blank samples alike in the smoothing parameter selection. Referencing 794 atmospheric aerosol samples from seven Interagency Monitoring of PROtected Visual Environment (IMPROVE) sites collected during 2011, we start by identifying key FT-IR signal characteristics, such as non-negative absorbance or analyte segment transformation, to capture sample-specific transitions between background and analyte. While referring to qualitative properties of PTFE background, the goal of smoothing splines interpolation is to learn the baseline structure in the background region to predict the baseline structure in the analyte region. We then validate the model by comparing smoothing splines baseline-corrected spectra with uncorrected and polynomial baseline (PB)-corrected equivalents via three statistical applications: (1) clustering analysis, (2) functional group quantification

  17. Baseline sociodemographic characteristics of participants and dropout in Web-based weight reduction program in Serbia

    OpenAIRE

    Dragana Brdaric

    2015-01-01

    BACKGROUND: Standard treatments of obesity are becoming very large economic burden to the health systems even in the most developed countries (Finkelstein, Trogdon, Cohen & Dietz, 2009) and are available only to a limited number of people (Manzoni et al., 2011; Womble et al., 2004). Having that in mind, the use of digital technology and the Internet has the potential to provide cost-effective and accessible weight reduction treatment. However, overview of research highlights several issues...

  18. Baseline sociodemographic characteristics of participants and dropout in Web-based weight reduction program in Serbia

    Directory of Open Access Journals (Sweden)

    Dragana Brdaric

    2015-10-01

    The findings show that the majority of participants of web-based weight loss program Health on menu were adult women who are highly educated. The average BMI of the respondents fall into the category of overweight. The findings demonstrate very high prevalence of attrition among participants. Given that this is the first time that this kind of web based program is introduced to Serbian participants, these results emphasize the importance of further continuation of such research. Also, those preliminary results highlight the need for evidence-based strategies in order to improve use of web based weight loss programs.

  19. Lifestyle interventions and independence for elders study: Recruitment and baseline characteristics

    Science.gov (United States)

    Recruitment of older adults into long-term clinical trials involving behavioral interventions is a significant challenge. The Lifestyle Interventions and Independence for Elders (LIFE) Study is a Phase 3 multicenter randomized controlled multisite trial, designed to compare the effects of a moderate...

  20. Impact of baseline characteristics on outcomes of carotid artery stenting in acute ischemic stroke patients

    OpenAIRE

    Lu, Henry Horng-Shing

    2016-01-01

    Cheng-Sheng Yu,1,* Chih-Ming Lin,2,3,* Chi-Kuang Liu,4 Henry Horng-Shing Lu1 1Institute of Statistics and Big Data Research Center, National Chiao Tung University, Hsinchu, 2Stroke Centre and Department of Neurology, Chunghua Christian Hospital, Chunghua, 3Graduate Institute of Biological Science and Technology, National Chiao Tung University, Hsinchu, 4Department of Medical Imaging, Chunghua Christian Hospital, Chunghua, Taiwan, Republic of China *These authors contributed equally to&n...

  1. Impact of baseline characteristics on outcomes of carotid artery stenting in acute ischemic stroke patients

    OpenAIRE

    Yu CS; Lin CM; Liu CK; Lu HHS

    2016-01-01

    Cheng-Sheng Yu,1,* Chih-Ming Lin,2,3,* Chi-Kuang Liu,4 Henry Horng-Shing Lu1 1Institute of Statistics and Big Data Research Center, National Chiao Tung University, Hsinchu, 2Stroke Centre and Department of Neurology, Chunghua Christian Hospital, Chunghua, 3Graduate Institute of Biological Science and Technology, National Chiao Tung University, Hsinchu, 4Department of Medical Imaging, Chunghua Christian Hospital, Chunghua, Taiwan, Republic of China *These authors contributed equally to ...

  2. Hearing aid effectiveness after aural rehabilitation - individual versus group (HEARING) trial: RCT design and baseline characteristics

    OpenAIRE

    Heagerty Patrick J; Liu Chuan-Fen; Souza Pamela E; Collins Margaret P; Amtmann Dagmar; Yueh Bevan

    2009-01-01

    Abstract Background Hearing impairment is the most common body system disability in veterans. In 2008, nearly 520,000 veterans had a disability for hearing loss through the Department of Veterans Affairs (VA). Changes in eligibility for hearing aid services, along with the aging population, contributed to a greater than 300% increase in the number of hearing aids dispensed from 1996 to 2006. In 2006, the VA committed to having no wait times for patient visits while providing quality clinicall...

  3. Quality of life and baseline characteristics associated with depressive symptoms among patients with heart disease

    OpenAIRE

    Rejai, Sepehr; Giardino, Nicholas D; Krishnan, Sangeetha; Ockene, Ira S; Rubenfire, Melvyn; Jackson, Elizabeth A

    2012-01-01

    We sought to examine factors associated with depressive symptoms among patients with heart disease. Data from 197 patients admitted for coronary artery disease were examined using multivariate predictive models. Women and unmarried patients were more likely to report depressive symptoms. In multivariate models, we observed that depressive symptoms were associated with the level of tangible social (but not emotional) support, bodily pain, and vitality, but not the number of comorbidities, gend...

  4. Baseline characteristics and initial treatment decisions for patients with schizophrenia at risk of treatment nonadherence

    OpenAIRE

    Kelin, Kelin

    2010-01-01

    Katarina Kelin1, Alan JM Brnabic2, Richard Newton3, Raúl I Escamilla4, Liang-Jen Chuo5, Malina Simu6, Wenyu Ye2, William Montgomery1, Jamie Karagianis7, Haya Ascher-Svanum81Eli Lilly Australia Pty Ltd, West Ryde, NSW, Australia; 2Intercontinental Information Sciences, Eli Lilly Australia Pty Ltd, Macquarie Park, NSW, Australia; 3Peninsula Health Psychiatric Services, Frankston Hospital, Frankston, VIC, Australia (current affiliation: Department of Psychiatry, Austin Hospital, Heide...

  5. A general-purpose baseline estimation algorithm for spectroscopic data

    International Nuclear Information System (INIS)

    A common feature of many modern technologies used in proteomics - including nuclear magnetic resonance imaging and mass spectrometry - is the generation of large amounts of data for each subject in an experiment. Extracting the signal from the background noise, however, poses significant challenges. One important part of signal extraction is the correct identification of the baseline level of the data. In this article, we propose a new algorithm (the 'BXR algorithm') for baseline estimation that can be directly applied to different types of spectroscopic data, but also can be specifically tailored to different technologies. We then show how to adapt the algorithm to a particular technology - matrix-assisted laser desorption/ionization Fourier transform ion cyclotron resonance mass spectrometry - which is rapidly gaining popularity as an analytic tool in proteomics. Finally, we compare the performance of our algorithm to that of existing algorithms for baseline estimation. The BXR algorithm is computationally efficient, robust to the type of one-sided signal that occurs in many modern applications (including NMR and mass spectrometry), and improves on existing baseline estimation algorithms. It is implemented as the function baseline in the R package FTICRMS, available either from the Comprehensive R Archive Network ( (http://www.r-project.org/)) or from the first author.

  6. LBCS: the LOFAR Long-Baseline Calibrator Survey

    CERN Document Server

    Jackson, N; Deller, A; Moldón, J; Varenius, E; Morabito, L; Wucknitz, O; Carozzi, T; Conway, J; Drabent, A; Kapinska, A; Orrù, E; Brentjens, M; Blaauw, R; Kuper, G; Sluman, J; Schaap, J; Vermaas, N; Iacobelli, M; Cerrigone, L; Shulevski, A; ter Veen, S; Fallows, R; Pizzo, R; Sipior, M; Anderson, J; Avruch, M; Bell, M; van Bemmel, I; Bentum, M; Best, P; Bonafede, A; Breitling, F; Broderick, J; Brouw, W; Brüggen, M; Ciardi, B; Corstanje, A; de Gasperin, F; de Geus, E; Eislöffel, J; Engels, D; Falcke, H; Garrett, M; Griessmeier, J; Gunst, A; van Haarlem, M; Heald, G; Hoeft, M; Hörandel, J; Horneffer, A; Intema, H; Juette, E; Kuniyoshi, M; van Leeuwen, J; Loose, G; Maat, P; McFadden, R; McKay-Bukowski, D; McKean, J; Mulcahy, D; Munk, H; Pandey-Pommier, M; Polatidis, A; Reich, W; Röttgering, H; Rowlinson, A; Scaife, A; Schwarz, D; Steinmetz, M; Swinbank, J; Thoudam, S; Toribio, M; Vermeulen, R; Vocks, C; van Weeren, R; Wise, M; Yatawatta, S; Zarka, P

    2016-01-01

    (abridged). We outline LBCS (the LOFAR Long-Baseline Calibrator Survey), whose aim is to identify sources suitable for calibrating the highest-resolution observations made with the International LOFAR Telescope, which include baselines >1000 km. Suitable sources must contain significant correlated flux density (50-100mJy) at frequencies around 110--190~MHz on scales of a few hundred mas. At least for the 200--300-km international baselines, we find around 1 suitable calibrator source per square degree over a large part of the northern sky, in agreement with previous work. This should allow a randomly selected target to be successfully phase calibrated on the international baselines in over 50% of cases. Products of the survey include calibrator source lists and fringe-rate and delay maps of wide areas -- typically a few degrees -- around each source. The density of sources with significant correlated flux declines noticeably with baseline length over the range 200--600~km, with good calibrators on the longest...

  7. Atmospheric pressure loading parameters from very long baseline interferometry observations

    Science.gov (United States)

    Macmillan, D. S.; Gipson, John M.

    1994-01-01

    Atmospheric mass loading produces a primarily vertical displacement of the Earth's crust. This displacement is correlated with surface pressure and is large enough to be detected by very long baseline interferometry (VLBI) measurements. Using the measured surface pressure at VLBI stations, we have estimated the atmospheric loading term for each station location directly from VLBI data acquired from 1979 to 1992. Our estimates of the vertical sensitivity to change in pressure range from 0 to -0.6 mm/mbar depending on the station. These estimates agree with inverted barometer model calculations (Manabe et al., 1991; vanDam and Herring, 1994) of the vertical displacement sensitivity computed by convolving actual pressure distributions with loading Green's functions. The pressure sensitivity tends to be smaller for stations near the coast, which is consistent with the inverted barometer hypothesis. Applying this estimated pressure loading correction in standard VLBI geodetic analysis improves the repeatability of estimated lengths of 25 out of 37 baselines that were measured at least 50 times. In a root-sum-square (rss) sense, the improvement generally increases with baseline length at a rate of about 0.3 to 0.6 ppb depending on whether the baseline stations are close to the coast. For the 5998-km baseline from Westford, Massachusetts, to Wettzell, Germany, the rss improvement is about 3.6 mm out of 11.0 mm. The average rss reduction of the vertical scatter for inland stations ranges from 2.7 to 5.4 mm.

  8. Baseline development, economic risk, and schedule risk: An integrated approach

    International Nuclear Information System (INIS)

    The economic and schedule risks of Environmental Restoration (ER) projects are commonly analyzed toward the end of the baseline development process. Risk analysis is usually performed as the final element of the scheduling or estimating processes for the purpose of establishing cost and schedule contingency. However, there is an opportunity for earlier assessment of risks, during development of the technical scope and Work Breakdown Structure (WBS). Integrating the processes of risk management and baselining provides for early incorporation of feedback regarding schedule and cost risk into the proposed scope of work. Much of the information necessary to perform risk analysis becomes available during development of the technical baseline, as the scope of work and WBS are being defined. The analysis of risk can actually be initiated early on during development of the technical baseline and continue throughout development of the complete project baseline. Indeed, best business practices suggest that information crucial to the success of a project be analyzed and incorporated into project planning as soon as it is available and usable

  9. Baseline brain activity fluctuations predict somatosensory perception in humans

    Science.gov (United States)

    Boly, M.; Balteau, E.; Schnakers, C.; Degueldre, C.; Moonen, G.; Luxen, A.; Phillips, C.; Peigneux, P.; Maquet, P.; Laureys, S.

    2007-01-01

    In perceptual experiments, within-individual fluctuations in perception are observed across multiple presentations of the same stimuli, a phenomenon that remains only partially understood. Here, by means of thulium–yttrium/aluminum–garnet laser and event-related functional MRI, we tested whether variability in perception of identical stimuli relates to differences in prestimulus, baseline brain activity. Results indicate a positive relationship between conscious perception of low-intensity somatosensory stimuli and immediately preceding levels of baseline activity in medial thalamus and the lateral frontoparietal network, respectively, which are thought to relate to vigilance and “external monitoring.” Conversely, there was a negative correlation between subsequent reporting of conscious perception and baseline activity in a set of regions encompassing posterior cingulate/precuneus and temporoparietal cortices, possibly relating to introspection and self-oriented processes. At nociceptive levels of stimulation, pain-intensity ratings positively correlated with baseline fluctuations in anterior cingulate cortex in an area known to be involved in the affective dimension of pain. These results suggest that baseline brain-activity fluctuations may profoundly modify our conscious perception of the external world. PMID:17616583

  10. Functional Testing Protocols for Commercial Building Efficiency Baseline Modeling Software

    Energy Technology Data Exchange (ETDEWEB)

    Jump, David; Price, Phillip N.; Granderson, Jessica; Sohn, Michael

    2013-09-06

    This document describes procedures for testing and validating proprietary baseline energy modeling software accuracy in predicting energy use over the period of interest, such as a month or a year. The procedures are designed according to the methodology used for public domain baselining software in another LBNL report that was (like the present report) prepared for Pacific Gas and Electric Company: ?Commercial Building Energy Baseline Modeling Software: Performance Metrics and Method Testing with Open Source Models and Implications for Proprietary Software Testing Protocols? (referred to here as the ?Model Analysis Report?). The test procedure focuses on the quality of the software?s predictions rather than on the specific algorithms used to predict energy use. In this way the software vendor is not required to divulge or share proprietary information about how their software works, while enabling stakeholders to assess its performance.

  11. CMB Experiment Baseline Determination by Minimizing Pixel Observations Dispersion

    CERN Document Server

    Smoot, G F

    1997-01-01

    This paper discusses a couple of approaches to removing instrument gain and baseline variation from observations of the CMB anisotropy. These techniques were tested on the COBE DMR data, a balloon experiment, and by monte carlo simulations. This work, though considered technical, is made available because CMB anisotropy mapping data processing is currently very active and a significant number of groups are working on this issue. Specifically, time-ordered estimates of the gain and baseline via fitting to limited sections of data or to the full or a large section of data are considered and compared. An expression is given for the correlation between pixels introduced by the residual baseline and removal technique.

  12. Baseline hydrocarbon levels in New Zealand coastal and marine avifauna.

    Science.gov (United States)

    McConnell, H M; Gartrell, B D; Chilvers, B L; Finlayson, S T; Bridgen, P C E; Morgan, K J

    2015-05-15

    The external effects of oil on wildlife can be obvious and acute. Internal effects are more difficult to detect and can occur without any external signs. To quantify internal effects from oil ingestion by wildlife during an oil spill, baseline levels of ubiquitous hydrocarbon fractions, like polycyclic aromatic hydrocarbons (PAHs), need to be established. With these baseline values the extent of impact from exposure during a spill can be determined. This research represents the first investigation of baseline levels for 22 PAHs in New Zealand coastal and marine avian wildlife. Eighty-five liver samples were tested from 18 species. PAHs were identified in 98% of livers sampled with concentrations ranging from 0 to 1341.6 ng/g lipid wt or on wet wt basis, 0 to 29.5 ng/g. Overall, concentrations were low relative to other globally reported avian values. PAH concentration variability was linked with species foraging habitat and migratory patterns. PMID:25707316

  13. Solar central electric power generation - A baseline design

    Science.gov (United States)

    Powell, J. C.

    1976-01-01

    The paper presents the conceptual technical baseline design of a solar electric power plant using the central receiver concept, and derives credible cost estimates from the baseline design. The major components of the plant - heliostats, tower, receiver, tower piping, and thermal storage - are discussed in terms of technical and cost information. The assumed peak plant output is 215 MW(e), over 4000 daylight hours. The contribution of total capital investment to energy cost is estimated to be about 55 mills per kwh in mid-1974 dollars.

  14. Subtracting Technique of Baselines for Capillary Electrophoresis Signals

    Institute of Scientific and Technical Information of China (English)

    WANG Ying; MO Jin-yuan; CHEN Zuan-guang; GAO Yan

    2004-01-01

    The drifting baselines of capillary electrophoresis affect the veracity of analysis greatly. This paper presents Threshold Fitting Technique(TFT) so as to subtract the baselines from the original signals and emendate the signals. In TFT, wav elet and curve fitting technique are applied synthetically, thresholds are decided by the computer automatically. Many experiments of signal processing indicate that TFT is simple for being used, there are few man-induced factors, and the results are satisfactory. TFT can be applied for noisy signals without any pre-processing.

  15. Future long-baseline neutrino oscillations: View from Asia

    International Nuclear Information System (INIS)

    Accelerator based long-baseline neutrino oscillation experiments have been playing important roles in revealing the nature of neutrinos. However, it turned out that the current experiments are not sufficient to study two major remaining problems, the CP violation in the lepton sector and the mass hierarchy of neutrinos. Therefore, several new experiments have been proposed. Among of them, two accelerator based long-baseline neutrino oscillation experiments, the J-PARC neutrino beam and Hyper-Kamiokande, and MOMENT, have been proposed in Asia. These two projects are reviewed in this article

  16. Detecting dark energy in long baseline neutrino oscillations

    Institute of Scientific and Technical Information of China (English)

    GU Pei-Hong; BI Xiao-Jun; FENG Bo; YOUNG Bing-Lin; ZHANG Xin-Min

    2008-01-01

    In this paper, we discuss a possibility of studying properties of dark energy in long baseline neutrino oscillation experiments. We consider two types of models of neutrino dark energy. For one type of models the scalar field is taken to be quintessence-like and for the other phantom-like. In these models the scalar fields couple to the neutrinos to give rise to spatially varying neutrino masses. We will show that the two types of models predict different behaviors of the spatial variation of the neutrino masses inside the Earth and consequently result in different signals in long baseline neutrino oscillation experiments.

  17. Way to increase the user access at the LCLS baseline

    International Nuclear Information System (INIS)

    Although the LCLS photon beam is meant for a single user, the baseline undulator is long enough to serve two users simultaneously. To this end, we propose a setup composed of two simple elements: an X-ray mirror pair for X-ray beam deflection, and a short (4 m-long) magnetic chicane, which creates an offset for mirror pair installation in the middle of the baseline undulator. The insertable mirror pair can be used for spatial separation of the X-ray beams generated in the first and in the second half of the baseline undulator. The method of deactivating one half and activating another half of the undulator is based on the rapid switching of the FEL amplification process. As proposed elsewhere, using a kicker installed upstream of the LCLS baseline undulator and an already existing corrector in the first half of the undulator, it is possible to rapidly switch the X-ray beam from one user to another, thus providing two active beamlines at any time. We present simulation results dealing with the LCLS baseline, and show that it is possible to generate two saturated SASE X-ray beams in the whole 0.8-8 keV photon energy range in the same baseline undulator. These can be exploited to serve two users. Implementation of the proposed technique does not perturb the baseline mode of operation of the LCLS undulator. Moreover, the magnetic chicane setup is very flexible, and can be used as a self-seeding setup too. We present simulation results for the LCLS baseline undulator with SHAB (second harmonic afterburner) and show that one can produce monochromatic radiation at the 2nd harmonic as well as at the 1st. We describe an efficient way for obtaining multi-user operation at the LCLS hard X-ray FEL. To this end, a photon beam distribution system based on the use of crystals in the Bragg reflection geometry is proposed. The reflectivity of crystal deflectors can be switched fast enough by flipping the crystals with piezoelectric devices similar to those for X-ray phase retarders

  18. 200-BP-5 operable unit Technical Baseline report

    Energy Technology Data Exchange (ETDEWEB)

    Jacques, I.D.; Kent, S.K.

    1991-10-01

    This report supports development of a remedial investigation/feasibility study work plan for the 200-BP-5 operable unit. The report summarizes baseline information for waste sites and unplanned release sites located in the 200-BP-5 operable unit. The sites were investigated by the Technical Baseline Section of the Environmental Engineering Group, Westinghouse Hanford Company (Westinghouse Hanford). The investigation consisted of review and evaluation of current and historical Hanford Site reports, drawings, and photographs, and was supplemented with recent inspections of the Hanford Site and employee interviews. No field investigations or sampling were conducted.

  19. 200-BP-5 operable unit Technical Baseline report

    International Nuclear Information System (INIS)

    This report supports development of a remedial investigation/feasibility study work plan for the 200-BP-5 operable unit. The report summarizes baseline information for waste sites and unplanned release sites located in the 200-BP-5 operable unit. The sites were investigated by the Technical Baseline Section of the Environmental Engineering Group, Westinghouse Hanford Company (Westinghouse Hanford). The investigation consisted of review and evaluation of current and historical Hanford Site reports, drawings, and photographs, and was supplemented with recent inspections of the Hanford Site and employee interviews. No field investigations or sampling were conducted

  20. Salton Sea sampling program: baseline and toxicity studies

    Energy Technology Data Exchange (ETDEWEB)

    Tullis, R.E.

    1977-09-30

    Baseline data on several of the Salton Sea fishes are reported. Morphometric (dimensions) and meristic (counting elements) data are presented as a baseline to evaluate any accumulation and physiological stresses that the fishes may experience as a result of geothermal development. Trace elements were analyzed in selected tissues or whole fish. The trace elements evaluated were K, Cu, Fe, Cu, Zn, Br, Rb, Sr, and Pb. The major fishes studied were corvina (Cynoscion xanthulus), gulf coaker (Bairdiella icistius, and molly (Poecilia latapinna). Other fishes occasionally tested were Tilapia sp. and sargo (Anisotremus davidsonii).

  1. Non-baseline damage detection from changes in strain energy mode shapes experiments on armored vehicle launched bridge

    International Nuclear Information System (INIS)

    There are several existing methods for damage detection based on identifying changes in strain energy mode shapes. Most of these methods require knowing strain energy mode shapes for a structure without damage in order to establish a baseline for damage detection. Usually, the mode shapes from the structure under test should be compared to the baseline mode shapes to identify and locate damage. However, these methods of damage detection are not very suitable for application on structures where baseline mode shapes cannot be readily obtained, for example, structures with preexisting damage. Conventional methods, like building a finite element model of a structure to be used as a baseline might be an expensive and time-consuming task that can be impossible for complex structures. A new (non-baseline) method for the extraction of localized changes (damage peaks) from strain energy mode shapes based on Fourier analysis of the strain energy mode shapes has been developed and analytically proved for the cases of a pinned-pinned and a free-free beam. The new method looks for characteristic changes in the power spectrum of the strain energy mode shapes in order to locate and identify damage. The analytical results have been confirmed both by the finite element model and impact testing experiments on a free-free aluminum beam, including single and multiple damage scenarios. This paper presents results of testing the non-baseline method on a complex structure -- Armored Vehicle Launched Bridge, which consists of loosely coupled hinged beams with variable cross-section. The results of testing confirm applicability of the non-baseline method to damage detection in complex structures and highlight certain particularities of its use

  2. Overgeneral autobiographical memory at baseline predicts depressive symptoms at follow-up in patients with first-episode depression.

    Science.gov (United States)

    Liu, Yansong; Zhang, Fuquan; Wang, Zhiqiang; Cao, Leiming; Wang, Jun; Na, Aiguo; Sun, Yujun; Zhao, Xudong

    2016-09-30

    Previous studies have shown that overgeneral autobiographical memory (OGM) is a characteristic of depression. However, there are no studies to explore the association between baseline OGM and depressive symptoms at follow-up in patients with first-episode depression (FE). This study investigated whether baseline OGM predicts depressive symptoms at follow-up in patients with FE. We recruited 125 patients with FE. The participants were divided into remitted group and non-remitted group according to the severity of their depression at 12 months follow-up. The measures consisted of the 17-item Hamilton Depression Rating Scale, Ruminative Response Scale, and Autobiographical Memory Test. Hierarchical linear regression analyses and bootstrap mediation analyses were conducted. The results showed that non-remitted patients had more OGM at baseline. Baseline OGM predicted depressive symptoms at follow-up in patients with FE. Rumination mediated the relationship between baseline OGM and depressive symptoms at follow-up. Our findings highlight OGM as a vulnerability factor involved in the maintenance of depression in patients with FE. PMID:27392229

  3. Mixed waste focus area technical baseline report. Volume 1

    International Nuclear Information System (INIS)

    The Department of Energy (DOE) established the Mixed Waste Characterization, Treatment, and Disposal Focus Area (MWFA) to develop and facilitate implementation of technologies required to meet the Department's commitments for treatment of mixed low-level and transuranic wastes. The mission of the MWFA is to provide acceptable technologies, developed in partnership with end-users, stakeholders, tribal governments, and regulators, that enable implementation of mixed waste treatment systems. To accomplish this mission, a technical baseline was established in 1996 that forms the basis for determining which technology development activities will be supported by the MWFA. This technical baseline is revised on an annual basis to reflect changes in the DOE Mixed Waste Management strategies, changes in the MWFA technical baseline development process, and MWFA accomplishments. This report presents the first revision to the technical baseline and the resulting prioritized list of deficiencies that the MWFA will address. This report also reflects a higher level of stakeholder involvement in the prioritization of the deficiencies. This document summarizes the data and the assumptions upon which this work was based, as well as information concerning the DOE Office of Environmental Management (EM) mixed waste technology development needs

  4. Cognitive performance baseline measurement and eye movement performance measures

    Science.gov (United States)

    Viirre, Erik S.; Chase, Bradley; Tsai, Yi-Fang

    2005-05-01

    Personnel are often required to perform multiple simultaneous tasks at the limits of their cognitive capacity. In research surrounding cognitive performance resources for tasks during stress and high cognitive workload, one area of deficiency is measurement of individual differences. To determine the amount of attentional demand a stressor places on a subject, one must first know that all subjects are performing at the same level with the same amount of available capacity in the control condition. By equating the baselines of performance across all subjects ("baselining") we can control for differing amounts of performance capacity or attentional resources in each individual. For example, a given level of task performance without a time restriction may be equated across subjects to account for attentional resources. Training to a fixed level of proficiency with time limits might obliterate individual differences in mental resources. Eye movement parameters may serve as a real-time measure of attentional demand. In implementing a baselining technique to control for individual differences, eye movement behaviors will be associated with the true cognitive demands of task loading or other stressors. Using eye movement data as a proxy for attentional state, it may be possible to "close the loop" on the human-machine system, providing a means by which the system can adapt to the attentional state of the human operator. In our presentation, eye movement data will be shown with and without the benefit of the baselining technique. Experimental results will be discussed within the context of this theoretical framework.

  5. Synthesizing SMOS Zero-Baselines with Aquarius Brightness Temperature Simulator

    Science.gov (United States)

    Colliander, A.; Dinnat, E.; Le Vine, D.; Kainulainen, J.

    2012-01-01

    SMOS [1] and Aquarius [2] are ESA and NASA missions, respectively, to make L-band measurements from the Low Earth Orbit. SMOS makes passive measurements whereas Aquarius measures both passive and active. SMOS was launched in November 2009 and Aquarius in June 2011.The scientific objectives of the missions are overlapping: both missions aim at mapping the global Sea Surface Salinity (SSS). Additionally, SMOS mission produces soil moisture product (however, Aquarius data will eventually be used for retrieving soil moisture too). The consistency of the brightness temperature observations made by the two instruments is essential for long-term studies of SSS and soil moisture. For resolving the consistency, the calibration of the instruments is the key. The basis of the SMOS brightness temperature level is the measurements performed with the so-called zero-baselines [3]; SMOS employs an interferometric measurement technique which forms a brightness temperature image from several baselines constructed by combination of multiple receivers in an array; zero-length baseline defines the overall brightness temperature level. The basis of the Aquarius brightness temperature level is resolved from the brightness temperature simulator combined with ancillary data such as antenna patterns and environmental models [4]. Consistency between the SMOS zero-baseline measurements and the simulator output would provide a robust basis for establishing the overall comparability of the missions.

  6. 48 CFR 334.202 - Integrated Baseline Reviews (IBRs).

    Science.gov (United States)

    2010-10-01

    ... Integrated Baseline Reviews (IBRs). (a) An IBR normally should be conducted as a post-award activity. A pre-award IBR may be conducted only if— (1) The AP contains documentation that demonstrates the need and rationale for a pre-award IBR, including an assessment of the impact on the source selection schedule...

  7. 48 CFR 34.202 - Integrated Baseline Reviews.

    Science.gov (United States)

    2010-10-01

    ... Review (IBR). (b) The purpose of the IBR is to verify the technical content and the realism of the..., and it should formulate a plan to handle these risks. (c) The IBR is a joint assessment by the offeror... planning and baseline control. (d) The timing and conduct of the IBR shall be in accordance with...

  8. Baseline Gas Turbine Development Program. Eleventh quarterly progress report

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, F.W.; Wagner, C.E.

    1975-07-31

    Progress is reported for a program to demonstrate by 1976 an experimental gas turbine powered automobile which meets the 1978 Federal Emissions Standards, has significantly improved fuel economy, and is competitive in performance, reliability, and potential manufacturing cost with the conventional piston engine powered, standard size American automobile. NASA completed initial heat balance testing of a baseline engine. An additional 450 hours were run on ceramic regenerators and seals. Seal wear rates are very good, and the elastomeric mounting system was satisfactory. An engine/control oil supply system based on the power steering pump is successfully operating in baseline vehicles. The design of the upgraded engine power turbine nozzle actuator was finalized, and layouts of the inlet guide vane actuator are in process. A lock-up torque converter was installed in the free rotor vehicle. Baseline engine and vehicle testing of water injection and variable inlet guide vanes was completed. A thermal analysis of the gas generator is in process. A steady-state, full power analysis was made. A three-dimensional stress analysis of the compressor cover was made. The power turbine nozzle actuating system layout was completed. The analytical studies of the power turbine rotor bearings were completed. MTI completed the design of the gas generator rotor simulation fixture and is starting to build it. Optimized reduction gears were successfully tested in a baseline engine.

  9. The Dutch CAFE baseline: In or out of line?

    NARCIS (Netherlands)

    Jimmink BA; Folkert RJM; Thomas R; Beck JP; Eerdt MM van; Elzenga HE; Hoek KW van der; Hoen A; Peek CJ; LED; KMD; NMD; LVM; RIM; LDL

    2004-01-01

    The European Commission is constructing a strategy on air pollution within the Clean Air For Europe (CAFE) programme. This strategy will be based on assessments using the RAINS model for different policy ambitions where the CAFE baseline scenario and control strategies are employed. The Netherlands

  10. Baseline design of an OTEC pilot plantship. Volume C. Specifications

    Energy Technology Data Exchange (ETDEWEB)

    Glosten, L. R.; Bringloe, Thomas; Soracco, Dave; Fenstermacher, Earl; Magura, Donald; Sander, Olof; Richards, Dennis; Seward, Jerry

    1979-05-01

    Volume C is part of a three-volume report that presents a baseline engineering design of an Ocean Thermal Energy Conversion (OTEC) plantship. This volume provides the specifications for the hull, cold-water pipe, ship outfitting and machinery, OTEC power system, electrical system, and folded-tube heat exchangers.

  11. Technical Baseline Summary Description for the Tank Farm Contractor

    International Nuclear Information System (INIS)

    This document is a revision of the document titled above, summarizing the technical baseline of the Tank Farm Contractor. It is one of several documents prepared by CH2M HILL Hanford Group, Inc. to support the U.S. Department of Energy Office of River Protection Tank Waste Retrieval and Disposal Mission at Hanford

  12. The physicochemical basis of QSARs for baseline toxicity.

    Science.gov (United States)

    Mackay, D; Arnot, J A; Petkova, E P; Wallace, K B; Call, D J; Brooke, L T; Veith, G D

    2009-01-01

    The physico-chemical properties relevant to the equilibrium partitioning (bioconcentration) of chemicals between organisms and their respired media of water and air are reviewed and illustrated for chemicals that range in hydrophobicity. Relationships are then explored between freely dissolved external concentrations such as LC50s and chemical properties for one important toxicity mechanism, namely baseline toxicity or narcosis. The 'activity hypothesis' proposed by Ferguson in 1939 provides a coherent and compelling explanation for baseline toxicity of chemicals in both water- and air-respiring organisms, as well as a reference point for identifying more specific toxicity pathways. From inhalation studies with fish and rodents, narcosis is shown to occur at a chemical activity exceeding approximately 0.01 and there is no evidence of narcosis at activities less than 0.001. The activity hypothesis provides a framework for directly comparing the toxic potency of chemicals in both air- and water-breathing animals. The activity hypothesis is shown to be consistent with the critical body residue concept, but it has the advantage of avoiding the confounding effect of lipid content of the test organism. It also provides a theoretically sound basis for assessing the baseline toxicity of mixtures. It is suggested that since activity is readily calculated from fugacity, observed or predicted environmental abiotic and biotic fugacities can be used to evaluate the potential for baseline toxicity. Further, models employing fugacity or activity can be used to improve the experimental design of bioassays, thus possibly reducing unnecessary animal testing. PMID:19544198

  13. The First Very Long Baseline Interferometric SETI Experiment

    Science.gov (United States)

    Rampadarath, H.; Morgan, J. S.; Tingay, S. J.; Trott, C. M.

    2012-08-01

    The first Search for Extra-Terrestrial Intelligence (SETI) conducted with very long baseline interferometry (VLBI) is presented. By consideration of the basic principles of interferometry, we show that VLBI is efficient at discriminating between SETI signals and human generated radio frequency interference (RFI). The target for this study was the star Gliese 581, thought to have two planets within its habitable zone. On 2007 June 19, Gliese 581 was observed for 8 hr at 1230-1544 MHz with the Australian Long Baseline Array. The data set was searched for signals appearing on all interferometer baselines above five times the noise limit. A total of 222 potential SETI signals were detected and by using automated data analysis techniques were ruled out as originating from the Gliese 581 system. From our results we place an upper limit of 7 MW Hz-1 on the power output of any isotropic emitter located in the Gliese 581 system within this frequency range. This study shows that VLBI is ideal for targeted SETI including follow-up observations. The techniques presented are equally applicable to next-generation interferometers, such as the long baselines of the Square Kilometre Array.

  14. Revised SRC-I project baseline. Volume 2

    Energy Technology Data Exchange (ETDEWEB)

    1984-01-01

    The SRC Process Area Design Baseline consists of six volumes. The first four were submitted to DOE on 9 September 1981. The fifth volume, summarizing the Category A Engineering Change Proposals (ECPs), was not submitted. The sixth volume, containing proprietary information on Kerr-McGee's Critical Solvent Deashing System, was forwarded to BRHG Synthetic Fuels, Inc. for custody, according to past instructions from DOE, and is available for perusal by authorized DOE representatives. DOE formally accepted the Design Baseline under ICRC Release ECP 4-1001, at the Project Configuration Control Board meeting in Oak Ridge, Tennessee on 5 November 1981. The documentation was then revised by Catalytic, Inc. to incorporate the Category B and C and Post-Baseline Engineering Change Proposals. Volumes I through V of the Revised Design Baseline, dated 22 October 1982, are nonproprietary and they were issued to the DOE via Engineering Change Notice (ECN) 4-1 on 23 February 1983. Volume VI again contains proprieary information on Kerr-McGee Critical Solvent Deashing System; it was issued to Burns and Roe Synthetic Fuels, Inc. Subsequently, updated process descriptions, utility summaries, and errata sheets were issued to the DOE and Burns and Roe Synthetic Fuels, Inc. on nonproprietary Engineering Change Notices 4-2 and 4-3 on 24 May 1983.

  15. Medium baseline reactor neutrino experiments with two identical detectors

    International Nuclear Information System (INIS)

    In the next 10 years medium baseline reactor neutrino experiments will attempt to determine the neutrino mass hierarchy and to precisely measure θ12. Both of these determinations will be more reliable if data from identical detectors at distinct baselines are combined. While interference effects can be eliminated by choosing detector sites orthogonal to the reactor arrays, one of the greatest challenges facing a determination of the mass hierarchy is the detector's unknown energy response. By comparing peaks at similar energies at two identical detectors at distinct baselines, one eliminates any correlated dependence upon a monotonic energy response. In addition, a second detector leads to new hierarchy-dependent observables, such as the ratio of the locations of the maxima of the Fourier cosine transforms. A second detector at a distinct baseline also breaks the degeneracy between θ12 and the background neutrino flux from, for example, distant reactors and increases the effective target mass, which is limited by current designs to about 20 kton/detector

  16. 241-AZ Farm Annulus Extent of Condition Baseline Inspection

    Energy Technology Data Exchange (ETDEWEB)

    Engeman, Jason K.; Girardot, Crystal L.; Vazquez, Brandon J.

    2013-05-15

    This report provides the results of the comprehensive annulus visual inspection for tanks 241- AZ-101 and 241-AZ-102 performed in fiscal year 2013. The inspection established a baseline covering about 95 percent of the annulus floor for comparison with future inspections. Any changes in the condition are also included in this document.

  17. Technical Baseline Summary Description for the Tank Farm Contractor

    Energy Technology Data Exchange (ETDEWEB)

    TEDESCHI, A.R.

    2000-04-21

    This document is a revision of the document titled above, summarizing the technical baseline of the Tank Farm Contractor. It is one of several documents prepared by CH2M HILL Hanford Group, Inc. to support the U.S. Department of Energy Office of River Protection Tank Waste Retrieval and Disposal Mission at Hanford.

  18. An Overview of the 2014 ALMA Long Baseline Campaign

    CERN Document Server

    Partnership, ALMA; Vlahakis, C; Corder, S; Remijan, A; Barkats, D; Lucas, R; Hunter, T R; Brogan, C L; Asaki, Y; Matsushita, S; Dent, W R F; Hills, R E; Phillips, N; Richards, A M S; Cox, P; Amestica, R; Broguiere, D; Cotton, W; Hales, A S; Hiriart, R; Hirota, A; Hodge, J A; Impellizzeri, C M V; Kern, J; Kneissl, R; Liuzzo, E; Marcelino, N; Marson, R; Mignano, A; Nakanishi, K; Nikolic, B; Perez, J E; Pérez, L M; Toledo, I; Aladro, R; Butler, B; Cortes, J; Cortes, P; Dhawan, V; Di Francesco, J; Espada, D; Galarza, F; Garcia-Appadoo, D; Guzman-Ramirez, L; Humphreys, E M; Jung, T; Kameno, S; Laing, R A; Leon, S; Mangum, J; Marconi, G; Nagai, H; Nyman, L -A; Perley, R; Radiszcz, M; Rodón, J A; Sawada, T; Takahashi, S; Tilanus, R P J; van Kempen, T; Vilaro, B Vila; Watson, L C; Wiklind, T; Gueth, F; Tatematsu, K; Wootten, A; Castro-Carrizo, A; Chapillon, E; Dumas, G; de Gregorio-Monsalvo, I; Francke, H; Gallardo, J; Garcia, J; Gonzalez, S; Hibbard, J E; Hill, T; Kaminski, T; Karim, A; Krips, M; Kurono, Y; Lopez, C; Martin, S; Maud, L; Morales, F; Pietu, V; Plarre, K; Schieven, G; Testi, L; Videla, L; Villard, E; Whyborn, N; Zwaan, M A; Alves, F; Andreani, P; Avison, A; Barta, M; Bedosti, F; Bendo, G J; Bertoldi, F; Bethermin, M; Biggs, A; Boissier, J; Brand, J; Burkutean, S; Casasola, V; Conway, J; Cortese, L; Dabrowski, B; Davis, T A; Trigo, M Diaz; Fontani, F; Franco-Hernandez, R; Fuller, G; Madrid, R Galvan; Giannetti, A; Ginsburg, A; Graves, S F; Hatziminaoglou, E; Hogerheijde, M; Jachym, P; Serra, I Jimenez; Karlicky, M; Klaasen, P; Kraus, M; Kunneriath, D; Lagos, C; Longmore, S; Leurini, S; Maercker, M; Magnelli, B; Vidal, I Marti; Massardi, M; Maury, A; Muehle, S; Muller, S; Muxlow, T; O'Gorman, E; Paladino, R; Petry, D; Pineda, J; Randall, S; Richer, J S; Rossetti, A; Rushton, A; Rygl, K; Monge, A Sanchez; Schaaf, R; Schilke, P; Stanke, T; Schmalzl, M; Stoehr, F; Urban, S; van Kampen, E; Vlemmings, W; Wang, K; Wild, W; Yang, Y; Iguchi, S; Hasegawa, T; Saito, M; Inatani, J; Mizuno, N; Asayama, S; Kosugi, G; Morita, K -I; Chiba, K; Kawashima, S; Okumura, S K; Ohashi, N; Ogasawara, R; Sakamoto, S; Noguchi, T; Huang, Y -D; Liu, S -Y; Kemper, F; Koch, P M; Chen, M -T; Chikada, Y; Hiramatsu, M; Iono, D; Shimojo, M; Komugi, S; Kim, J; Lyo, A -R; Muller, E; Herrera, C; Miura, R E; Ueda, J; Chibueze, J; Su, Y -N; Trejo-Cruz, A; Wang, K -S; Kiuchi, H; Ukita, N; Sugimoto, M; Kawabe, R; Hayashi, M; Miyama, S; Ho, P T P; Kaifu, N; Ishiguro, M; Beasley, A J; Bhatnagar, S; Braatz, J A; Brisbin, D G; Brunetti, N; Carilli, C; Crossley, J H; D'Addario, L; Meyer, J L Donovan; Emerson, D T; Evans, A S; Fisher, P; Golap, K; Griffith, D M; Hale, A E; Halstead, D; Hardy, E J; Hatz, M C; Holdaway, M; Indebetouw, R; Jewell, P R; Kepley, A A; Kim, D -C; Lacy, M D; Leroy, A K; Liszt, H S; Lonsdale, C J; Matthews, B; McKinnon, M; Mason, B S; Moellenbrock, G; Moullet, A; Myers, S T; Ott, J; Peck, A B; Pisano, J; Radford, S J E; Randolph, W T; Venkata, U Rao; Rawlings, M; Rosen, R; Schnee, S L; Scott, K S; Sharp, N K; Sheth, K J; Simon, R S; Tsutsumi, T; Wood, S J

    2015-01-01

    A major goal of the Atacama Large Millimeter/submillimeter Array (ALMA) is to make accurate images with resolutions of tens of milliarcseconds, which at submillimeter (submm) wavelengths requires baselines up to ~15 km. To develop and test this capability, a Long Baseline Campaign (LBC) was carried out from September to late November 2014, culminating in end-to-end observations, calibrations, and imaging of selected Science Verification (SV) targets. This paper presents an overview of the campaign and its main results, including an investigation of the short-term coherence properties and systematic phase errors over the long baselines at the ALMA site, a summary of the SV targets and observations, and recommendations for science observing strategies at long baselines. Deep ALMA images of the quasar 3C138 at 97 and 241 GHz are also compared to VLA 43 GHz results, demonstrating an agreement at a level of a few percent. As a result of the extensive program of LBC testing, the highly successful SV imaging at long...

  19. Future short-baseline sterile neutrino searches with accelerators

    International Nuclear Information System (INIS)

    A number of experimental anomalies in neutrino oscillation physics point to the existence of at least one light sterile neutrino. This hypothesis can be precisely tested using neutrinos from reactors, radioactive isotopes, and particle accelerators. The focus of these proceedings is on future dedicated short-baseline sterile neutrino searches using accelerators

  20. Revised SRC-I project baseline. Volume 1

    Energy Technology Data Exchange (ETDEWEB)

    1984-01-01

    International Coal Refining Company (ICRC), in cooperation with the Commonwealth of Kentucky has contracted with the United States Department of Energy (DOE) to design, build and operate a first-of-its-kind plant demonstrating the economic, environmental, socioeconomic and technical feasibility of the direct coal liquefaction process known as SRC-I. ICRC has made a massive commitment of time and expertise to design processes, plan and formulate policy, schedules, costs and technical drawings for all plant systems. These fully integrated plans comprise the Project Baseline and are the basis for all future detailed engineering, plant construction, operation, and other work set forth in the contract between ICRC and the DOE. Volumes I and II of the accompanying documents constitute the updated Project Baseline for the SRC-I two-stage liquefaction plant. International Coal Refining Company believes this versatile plant design incorporates the most advanced coal liquefaction system available in the synthetic fuels field. SRC-I two-stage liquefaction, as developed by ICRC, is the way of the future in coal liquefaction because of its product slate flexibility, high process thermal efficiency, and low consumption of hydrogen. The SRC-I Project Baseline design also has made important state-of-the-art advances in areas such as environmental control systems. Because of a lack of funding, the DOE has curtailed the total project effort without specifying a definite renewal date. This precludes the development of revised accurate and meaningful schedules and, hence, escalated project costs. ICRC has revised and updated the original Design Baseline to include in the technical documentation all of the approved but previously non-incorporated Category B and C and new Post-Baseline Engineering Change Proposals.

  1. Robust and precise baseline determination of distributed spacecraft in LEO

    Science.gov (United States)

    Allende-Alba, Gerardo; Montenbruck, Oliver

    2016-01-01

    Recent experience with prominent formation flying missions in Low Earth Orbit (LEO), such as GRACE and TanDEM-X, has shown the feasibility of precise relative navigation at millimeter and sub-millimeter levels using GPS carrier phase measurements with fixed integer ambiguities. However, the robustness and availability of the solutions provided by current algorithms may be highly dependent on the mission profile. The main challenges faced in the LEO scenario are the resulting short continuous carrier phase tracking arcs along with the observed rapidly changing ionospheric conditions, which in the particular situation of long baselines increase the difficulty of correct integer ambiguity resolution. To reduce the impact of these factors, the present study proposes a strategy based on a reduced-dynamics filtering of dual-frequency GPS measurements for precise baseline determination along with a dedicated scheme for integer ambiguity resolution, consisting of a hybrid sequential/batch algorithm based on the maximum a posteriori and integer aperture estimators. The algorithms have been tested using flight data from the GRACE, TanDEM-X and Swarm missions in order to assess their robustness to different formation and baseline configurations. Results with the GRACE mission show an average 0.7 mm consistency with the K/Ka-band ranging measurements over a period of more than two years in a baseline configuration of 220 km. Results with TanDEM-X data show an average of 3.8 mm consistency of kinematic and reduced-dynamic solutions in the along-track component over a period of 40 days in baseline configurations of 500 m and 75 km. Data from Swarm A and Swarm C spacecraft are largely affected by atmospheric scintillation and contain half cycle ambiguities. The results obtained under such conditions show an overall consistency between kinematic and reduced-dynamic solutions of 1.7 cm in the along-track component over a period of 30 days in a variable baseline of approximately 60

  2. Prediction of clinical outcome with baseline and 24-hour perfusion CT in acute middle cerebral artery territory ischemic stroke treated with intravenous recanalization therapy

    International Nuclear Information System (INIS)

    We sought to determine whether Alberta Stroke Program Early CT Scores (ASPECTS) derived from baseline noncontrast CT (NCCT) and perfusion CT (CTP) imaging maps can predict clinical outcome after recanalization therapy in acute ischemic stroke of the middle cerebral artery (MCA) territory and whether changes in the ASPECTS from baseline to 24 h after recanalization therapy can help predict clinical outcome. We retrospectively studied consecutive patients with acute ischemic stroke of the MCA territory treated with intravenous tissue plasminogen activator (t-PA) or abciximab within 6 h of symptom onset. We performed NCCT and CTP before and 24 h after intravenous t-PA or abciximab treatment and determined the ASPECTS and the changes in the ASPECTS from baseline to 24 h. A favorable outcome was defined as a modified Rankin scale score of 0 or 1 at 3 months. During the 18-month study period 44 patients were studied. In multivariate logistic regression analysis, the cerebral blood volume (CBV) ASPECTS (OR 1.80, 95% CI 1.10 to 2.93) at baseline and the increase in cerebral blood flow (CBF) ASPECTS (OR 1.68, 95% CI 1.13 to 2.50) from baseline to 24 h were associated with a favorable outcome. The cutoff values for a favorable outcome using receiver operating characteristic curves were 8 and 1, respectively. When the CBV ASPECTS at baseline was 8 or more, its positive predictive value was only 58.1%. When the CBV ASPECTS at baseline was 8 or more and the increase in CBF ASPECTS from baseline to 24 h was 1 or more, the positive predictive value was 100% and the negative predictive value was 74.2%. The CBV ASPECTS derived from baseline CTP maps was found to be predictive of a favorable outcome, but its positive predictive value was suboptimal. The change in the CBF ASPECTS from baseline to 24 h after treatment was helpful in predicting outcome. (orig.)

  3. Baseline Differences and Trajectories of Change for Deceased, Placed, and Community Residing Alzheimer’s Disease Patients

    OpenAIRE

    Schulz, Richard; Zdaniuk, Bozena; Belle, Steven H; Czaja, Sara J.; Arrighi, H Michael; Arthur S. Zbrozek

    2010-01-01

    This study identifies predictors of placement or death in a large ethnically/racially diverse sample of moderately impaired Alzheimer’s disease (AD) patients residing in the community. Patients and caregivers were followed for 18 months with four assessments at six month intervals. Multinomial regression was used to identify caregiver and patient baseline characteristics and changes over time as predictors of patient placement in a long-term care facility (n=180), patient death (not preceded ...

  4. Baseline ecological risk assessment Salmon Site, Lamar County, Mississippi

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-04-01

    The Salmon Site (SS), formerly the Tatum Dome Test Site, located in Mississippi was the site of two nuclear and two gas explosion tests conducted between 1964 and 1970. A consequence of these testing activities is that radionuclides were released into the salt dome, where they are presently contained. During reentry drilling and other site activities, incidental liquid and solid wastes that contained radioactivity were generated, resulting in some soil, ground water and equipment contamination. As part of the remedial investigation effort, a Baseline Ecological Risk Assessment was conducted at the SS. The purpose is to gauge ecological and other environmental impacts attributable to past activities at the former test facility. The results of this facility-specific baseline risk assessment are presented in this document.

  5. Constraining the nonstandard interaction parameters in long baseline neutrino experiments

    Science.gov (United States)

    Huitu, Katri; Kärkkäinen, Timo J.; Maalampi, Jukka; Vihonen, Sampsa

    2016-03-01

    In this article we investigate the prospects for probing the strength of the possible nonstandard neutrino interactions (NSI) in long baseline neutrino oscillation experiments. We find that these experiments are sensitive to NSI couplings down to the level of 0.01-0.1 depending on the oscillation channel and the baseline length, as well as on the detector's fiducial mass. We also investigate the interference of the leptonic C P angle δC P with the constraining of the NSI couplings. It is found that the interference is strong in the case of the νe↔νμ and νe↔ντ transitions but not significant in other transitions. In our numerical analysis we apply the GLoBES software and use the LBNO setup as our benchmark.

  6. Fissile materials disposition program plutonium immobilization project baseline formulation

    Energy Technology Data Exchange (ETDEWEB)

    Ebbinghaus, B B; Armantrout, G A; Gray, L; Herman, C C; Shaw, H F; Van Konynenburg, R A

    2000-09-01

    Since 1994 Lawrence Livermore National Laboratory (LLNL), with the help of several other laboratories and university groups, has been the lead laboratory for the Plutonium Immobilization Project (PIP). This involves, among other tasks, the development of a formulation and a fabrication process for a ceramic to be used in the immobilization of excess weapons-usable plutonium. This report reviews the history of the project as it relates to the development of the ceramic form. It describes the sample test plan for the pyrochlore-rich ceramic formulation that was selected, and it specifies the baseline formulation that has been adopted. It also presents compositional specifications (e.g. precursor compositions and mixing recipes) and other form and process specifications that are linked or potentially linked to the baseline formulation.

  7. Coral reef baselines: how much macroalgae is natural?

    Science.gov (United States)

    Bruno, John F; Precht, William F; Vroom, Peter S; Aronson, Richard B

    2014-03-15

    Identifying the baseline or natural state of an ecosystem is a critical step in effective conservation and restoration. Like most marine ecosystems, coral reefs are being degraded by human activities: corals and fish have declined in abundance and seaweeds, or macroalgae, have become more prevalent. The challenge for resource managers is to reverse these trends, but by how much? Based on surveys of Caribbean reefs in the 1970s, some reef scientists believe that the average cover of seaweed was very low in the natural state: perhaps less than 3%. On the other hand, evidence from remote Pacific reefs, ecological theory, and impacts of over-harvesting in other systems all suggest that, historically, macroalgal biomass may have been higher than assumed. Uncertainties about the natural state of coral reefs illustrate the difficulty of determining the baseline condition of even well studied systems. PMID:24486044

  8. Baseline ecological risk assessment Salmon Site, Lamar County, Mississippi

    International Nuclear Information System (INIS)

    The Salmon Site (SS), formerly the Tatum Dome Test Site, located in Mississippi was the site of two nuclear and two gas explosion tests conducted between 1964 and 1970. A consequence of these testing activities is that radionuclides were released into the salt dome, where they are presently contained. During reentry drilling and other site activities, incidental liquid and solid wastes that contained radioactivity were generated, resulting in some soil, ground water and equipment contamination. As part of the remedial investigation effort, a Baseline Ecological Risk Assessment was conducted at the SS. The purpose is to gauge ecological and other environmental impacts attributable to past activities at the former test facility. The results of this facility-specific baseline risk assessment are presented in this document

  9. International data transfer for space very long baseline interferometry

    Science.gov (United States)

    Wiercigroch, Alexandria B.

    1994-11-01

    Space very long baseline interferometry (SVLBI) experiments using a TDRSS satellite have successfully demonstrated the capability of using spacecraft to extend the effective baseline length of VLBI observations beyond the diameter of the Earth, thereby improving the resolution for imaging of active galactic nuclei at centimeter wavelengths. As a result, two spacecraft dedicated to SVLBI, VSOP (Japan) and RadioAstron (Russia), are scheduled to be launched into high Earth orbit in 1996 and 1997. The success of these missions depends on the cooperation of the international community in providing support from ground tracking stations, ground radio telescopes, and correlation facilities. The timely exchange and monitoring of data among the participants requires a well-designed and automated international data transfer system. In this paper, we will discuss the design requirements, data types and flows, and the operational responsibilities associated with the SVLBI data transfer system.

  10. Technical baseline description for in situ vitrification laboratory test equipment

    International Nuclear Information System (INIS)

    IN situ vitrification (ISV) has been identified as possible waste treatment technology. ISV was developed by Pacific Northwest Laboratory (PNL), Richland, Washington, as a thermal treatment process to treat contaminated soils in place. The process, which electrically melts and dissolves soils and associated inorganic materials, simultaneously destroys and/or removes organic contaminants while incorporating inorganic contaminants into a stable, glass-like residual product. This Technical Baseline Description has been prepared to provide high level descriptions of the design of the Laboratory Test model, including all design modifications and safety improvements made to data. Furthermore, the Technical Baseline Description provides a basic overview of the interface documents for configuration management, program management interfaces, safety, quality, and security requirements. 8 figs

  11. Decomposition for emission baseline setting in China's electricity sector

    International Nuclear Information System (INIS)

    Decomposition analysis is used to generate carbon dioxide emission baselines in China's electricity sector to the year 2020. This is undertaken from the vantage point of the final consumer of electricity, and therefore considers factors influencing electricity demand, efficiency of generation, sources of energy used for generation purposes, and the effectiveness of transmission and distribution. It is found that since 1980, gains in efficiency of generation have been the most important factor affecting change in the emission intensity of electricity generated. Based upon known energy and economic policy, efficiency gains will continue to contribute to reductions in the emission intensity of electricity generated, however, fuel shifts to natural gas and increases in nuclear generation will further these trends into the future. The analysis confirms other sources in the literature that decomposition is an appropriate technique available for baseline construction, thereby suitable for the emerging carbon market and its related mechanisms

  12. Baseline groundwater chemistry : the Palaeogene of the Thames Basin

    OpenAIRE

    Bearcock, J.M.; Smedley, P. L.

    2010-01-01

    This report describes the regional geochemistry of groundwater from the Palaeogene aquifer of the Thames Basin. The aim of the study is to assess the likely natural baseline chemistry of the groundwater by identifying the dominant controlling processes. Data have been collected from strategic sampling of 19 new groundwater samples, along with collation, from various sources, of existing groundwater, rainfall, mineralogical and geochemical data. The Palaeogene aquifer results fr...

  13. Baseline groundwater chemistry : the Sherwood Sandstone of Devon and Somerset

    OpenAIRE

    Bearcock, J.M.; Smedley, P. L.

    2012-01-01

    This report describes the regional geochemistry of groundwater from the Sherwood Sandstone aquifer of Devon and Somerset. In order to assess the likely natural baseline chemistry of the groundwater in the area, information has been gathered from the strategic collection of 21 new groundwater samples, and from collation of existing groundwater, rainfall, mineralogical and geochemical data. The Sherwood Sandstone aquifer results from continental deposition during the early Triass...

  14. The Baseline Configuration of Project Management Information System

    OpenAIRE

    Bērziša, S

    2009-01-01

    The purpose of project management information systems is to facilitate development and management of projects as well as to provide operational project information. Project management information systems need to be configured according to project management requirements during their deployment. In order to reduce complexity of this task, a baseline configuration can be used as a starting point of the configuration process. The objective of this paper is to establish the b...

  15. Causal Inference from Longitudinal Studies with Baseline Randomization

    OpenAIRE

    2008-01-01

    We describe analytic approaches for study designs that, like large simple trials, can be better characterized as longitudinal studies with baseline randomization than as either a pure randomized experiment or a purely observational study. We (i) discuss the intention-to-treat effect as an effect measure for randomized studies, (ii) provide a formal definition of causal effect for longitudinal studies, (iii) describe several methods -- based on inverse probability weighting and g-estimation --...

  16. Tree edit distance as a baseline approach for paraphrase representation

    OpenAIRE

    Vila Rigat, Marta; Dras, Mark

    2012-01-01

    Finding an adequate paraphrase representation formalism is a challenging issue in Natural Language Processing. In this paper, we analyse the performance of Tree Edit Distance as a paraphrase representation baseline. Our experiments using Edit Distance Textual Entailment Suite show that, as Tree Edit Distance consists of a purely syntactic approach, paraphrase alternations not based on structural reorganizations do not find an adequate representation. They also show that there is much scope fo...

  17. Baseline Gas Turbine Development Program. Fifteenth quarterly progress report

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, F W; Wagner, C E

    1976-07-30

    Progress is reported for a research program to demonstrate an experimental gas turbine powered automobile which would meet the 1978 Federal Emissions Standards, have significantly improved fuel economy and be competitive in performance, reliability and potential manufacturing cost with the conventional piston engine powered, standard size American automobile. Chrysler Corporation's Sixth Generation Gas Turbine Engine, having been selected as most representative of the state-of-the-art at the beginning of this program, has been used as the Baseline Engine. This is a 4:1 pressure ratio regenerative engine with variable power turbine nozzles which meets the .41 HC, 3.4 CO, 3.0 NOx grams/mile original 1975 emissions standards. Baseline vehicles are intermediate-size, 4-door sedans modified to accept the turbine engines. The Baseline cars are being actively utilized in a variety of Bicentennial/Energy related displays and demonstrations. All Baseline Engine improvement tasks have been completed. Emissions tests using COED coal derived fuel were conducted. The first Upgraded Engine was assembled, installed in a test cell, and initial test runs up to 70% speed were conducted. Control of the gas generator shaft instabilities which have resulted in failures of the gas lubricated bearing, was demonstrated by providing a low spring rate, squeeze film damping, and reducing the motion restraint caused by thrust loadings. The power turbine shaft dynamics fixture was run successfully to 60,000 rpm. Conversion of the production cars for the Upgraded Engine is continuing. The two four-door cars are nearly complete.

  18. Baseline descriptions for LWR spent fuel storage, handling, and transportation

    International Nuclear Information System (INIS)

    Baseline descriptions for the storage, handling, and transportation of reactor spent fuel are provided. The storage modes described include light water reactor (LWR) pools, away-from-reactor basins, dry surface storage, reprocessing-facility interim storage pools, and deep geologic storage. Land and water transportation are also discussed. This work was sponsored by the Department of Energy/Office of Safeguards and Security as part of the Sandia Laboratories Fixed Facility Physical Protection Program. 45 figs, 4 tables

  19. Measurement of Baseline and Orientation between Distributed Aerospace Platforms

    OpenAIRE

    Wen-Qin Wang

    2013-01-01

    Distributed platforms play an important role in aerospace remote sensing, radar navigation, and wireless communication applications. However, besides the requirement of high accurate time and frequency synchronization for coherent signal processing, the baseline between the transmitting platform and receiving platform and the orientation of platform towards each other during data recording must be measured in real time. In this paper, we propose an improved pulsed duplex microwave ranging app...

  20. The baseline dataflow system of the ATLAS trigger and DAQ

    CERN Document Server

    Vermeulen, J C; Dos Anjos, A; Barisonzi, M; Beck, H P; Beretta, M; Blair, R; Bogaerts, J A C; Boterenbrood, H; Botterill, David R; Ciobotaru, M; Palencia-Cortezon, E; Cranfield, R; Crone, G J; Dawson, J; Di Girolamo, B; Dobinson, Robert W; Ermoline, Y; Ferrer, M L; Francis, D; Gadomski, S; Gameiro, S; Golonka, P; Gorini, B; Green, B; Gruwé, M; Haas, S; Haeberli, C; Hasegawa, Y; Hauser, R; Hinkelbein, C; Hughes-Jones, R E; Jansweijer, P; Joos, M; Kaczmarska, A; Knezo, E; Kieft, G; Korcyl, K; Kugel, A; Lankford, A; Lehmann, G; Le Vine, M J; Liu, W; Maeno, T; Losada-Maia, L; Mapelli, L; Martin, B; McLaren, R; Meirosu, C; Misiejuk, A; Mommsen, R K; Mornacchi, Giuseppe; Müller, M; Nagasaka, Y; Nakayoshi, K; Papadopoulos, I M; Petersen, J; De Matos-Lopes-Pinto, P; Prigent, D; Pérez-Réale, V; Schlereth, J L; Shimojima, M; Spiwoks, R; Stancu, S; Strong, J; Tremblet, L; Werner, P; Wickens, F J; Yasu, Y; Yu, M; Zobernig, H; Zurek, M

    2003-01-01

    In this paper the baseline design of the ATLAS High Level Trigger and Data Acquisition system with respect to the DataFlow aspects, as presented in the recently submitted ATLAS Trigger/DAQ/Controls Technical Design Report [1], is reviewed and recent results of testbed measurements and from modelling are discussed. [1] ATLAS-TDR-016; CERN-LHCC-2003-022, http://cdsweb.cern.ch/search.py?recid=616089

  1. Logistics Operations Management Center: Maintenance Support Baseline (LOMC-MSB)

    Science.gov (United States)

    Kurrus, R.; Stump, F.

    1995-01-01

    The Logistics Operations Management Center Maintenance Support Baseline is defined. A historical record of systems, applied to and deleted from, designs in support of future management and/or technical analysis is provided. All Flight elements, Ground Support Equipment, Facility Systems and Equipment and Test Support Equipment for which LOMC has responsibilities at Kennedy Space Center and other locations are listed. International Space Station Alpha Program documentation is supplemented. The responsibility of the Space Station Launch Site Support Office is established.

  2. IODINE SALT CONSUMPTION IN INDONESIAN HOUSEHOLDS: BASELINE HEALTH SURVEY 2007

    OpenAIRE

    Ni Ketut Aryastami; Dwi Susilowati; Yuslely Usman

    2012-01-01

    Background: Iodine Deficiency Disorder (100) reduction program has been implemented since 1976. According to the National Economic Survey 2002, the average consumption of iodized salt was 6. 26 grams. The results of Iodine Salt Survey (SGY) 2003 showed that the consumption of iodine salt at the household level was 73.2%, meanwhile, the baseline health survey (Riskesdas) 2007 showed there was reduction of iodine salt consumption towards 60.2%. Methods: Type of study was secondary data analysis...

  3. A Resilient Program technical baseline framework for future space systems

    Science.gov (United States)

    Nguyen, Tien M.; Guillen, Andy T.; Matsunaga, Sumner S.

    2015-05-01

    Recent Better Buying Power (BBP) initiative for improving DoD's effectiveness in developing complex systems includes "Owning the Technical Baseline" (OTB). This paper presents an innovative approach for the development of a "Resilient Program" Technical Baseline Framework (PTBF). The framework provides a recipe for generating the "Resilient Program2" Technical Baseline (PTB) components using the Integrated Program Management (IPM) approach to integrate Key Program Elements (KPEs)3 with System Engineering (SE) process/tools, acquisition policy/process/tools, Cost and Schedule estimating tools, DOD Architecture Framework (DODAF) process/tools, Open System Architecture (OSA) process/tools, Risk Management process/tools, Critical Chain Program Management (CCPM) process, and Earned Value Management System (EVMS) process/tools. The proposed resilient framework includes a matrix that maps the required tools/processes to technical features of a comprehensive reference U.S. DOD "owned" technical baseline. Resilient PTBF employs a new Open System Approach (OSAP) combining existing OSA4 and NOA (Naval Open Architecture) frameworks, supplemented by additional proposed OA (Open Architecture) principles. The new OSAP being recommended to SMC (Space and Missiles Systems Center) presented in this paper is referred to as SMC-OSAP5. Resilient PTBF and SMC-OSAP conform to U.S. DOD Acquisition System (DAS), Joint Capabilities Integration and Development System (JCIDS), and DODAF processes. The paper also extends Ref. 21 on "Program Resiliency" concept by describing how the new OSAP can be used to align SMC acquisition management with DOD BBP 3.0 and SMC's vison for resilient acquisition and sustainment efforts.

  4. Baseline brain activity fluctuations predict somatosensory perception in humans

    OpenAIRE

    Boly, M; Balteau, E.; Schnakers, C; Degueldre, C.; Moonen, G.; Luxen, A.; Phillips, C.; Peigneux, P; Maquet, P; Laureys, S.

    2007-01-01

    In perceptual experiments, within-individual fluctuations in perception are observed across multiple presentations of the same stimuli, a phenomenon that remains only partially understood. Here, by means of thulium–yttrium/aluminum–garnet laser and event-related functional MRI, we tested whether variability in perception of identical stimuli relates to differences in prestimulus, baseline brain activity. Results indicate a positive relationship between conscious perception of low-intensity so...

  5. Re-Creating Missing Population Baselines for Pacific Reef Sharks

    OpenAIRE

    Nadon, Marc O.; Baum, Julia K.; Williams, Ivor D.; Mcpherson, Jana M; Zgliczynski, Brian J.; Richards, Benjamin L.; Schroeder, Robert E.; Brainard, Russell E.

    2012-01-01

    Summary Abstract Sharks and other large predators are scarce on most coral reefs, but studies of their historical ecology provide qualitative evidence that predators were once numerous in these ecosystems. Quantifying density of sharks in the absence of humans (baseline) is, however, hindered by a paucity of pertinent time-series data. Recently researchers have used underwater visual surveys, primarily of limited spatial extent or nonstandard design, to infer negative associations between ree...

  6. Baseline Gas Turbine Development Program. Fourteenth quarterly progress report

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, F W; Wagner, C E

    1976-04-30

    Progress is reported for a Baseline Gas Turbine Development Program sponsored by the Heat Engine Systems Branch, Division of Transportation Energy Conservation (TEC) of the Energy Research and Development Administration (ERDA). Structurally, this program is made up of three parts: (1) documentation of the existing automotive gas turbine state-of-the-art; (2) conduction of an extensive component improvement program; and (3) utilization of the improvements in the design, and building of an Upgraded Engine capable of demonstrating program goals.

  7. Integrated Baseline System (IBS) Version 2.0: User guide

    Energy Technology Data Exchange (ETDEWEB)

    Bower, J.C. [Bower Software Services, Kennewick, WA (United States); Burford, M.J.; Downing, T.R.; Matsumoto, S.W.; Schrank, E.E.; Williams, J.R.; Winters, C.; Wood, B.M.

    1994-03-01

    The Integrated Baseline System (IBS) is an emergency management planning and analysis tool being developed under the direction of the Federal Emergency Management Agency. This User Guide explains how to start and use the IBS Program, which is designed to help civilian emergency management personnel to plan for and support their responses to a chemical-releasing event at a military chemical stockpile. The intended audience for this document is all users of the IBS, especially emergency management planners and analysts.

  8. Does Baseline Heart Rate Variability Reflect Stable Positive Emotionality?

    OpenAIRE

    Silvia, Paul J.; Jackson, Bryonna A.; Sopko, Rachel S.

    2014-01-01

    Several recent studies have found significant correlations, medium in effect size, between baseline heart rate variability (HRV) and measures of positive functioning, such as extraversion, agreeableness, and trait positive affectivity. Other research, however, has suggested an optimal level of HRV and found nonlinear effects. In the present study, a diverse sample of 239 young adults completed a wide range of measures that reflect positive psychological functioning, including personality trai...

  9. A moving baseline for evaluation of advanced coal extraction systems

    Science.gov (United States)

    Bickerton, C. R.; Westerfield, M. D.

    1981-01-01

    Results from the initial effort to establish baseline economic performance comparators for a program whose intent is to define, develop, and demonstrate advanced systems suitable for coal resource extraction beyond the year 2000 are reported. Systems used were selected from contemporary coal mining technology and from conservation conjectures of year 2000 technology. The analysis was also based on a seam thickness of 6 ft. Therefore, the results are specific to the study systems and the selected seam extended to other seam thicknesses.

  10. Search for Sterile Neutrinos at Long and Short Baselines

    CERN Document Server

    Stanco, Luca

    2016-01-01

    Neutrino physics is currently suffering from lack of knowledge from at least four major ingredients. One of them is the presence or not of new sterile neutrino states at the mass scale of around 1 eV. Settling this point should be the highest priority for the neutrino community. We will discuss the state-of-the art of experimental searches for sterile neutrinos with accelerators, both at long and short baselines.

  11. Baseline and cognition activated brain SPECT imaging in depression

    International Nuclear Information System (INIS)

    Purpose: To evaluate the regional cerebral blood flow (rCBF) abnormalities through the semiquantitative analysis of the baseline and cognition activated rCBF imaging in unmedicated depressed patients. Methods: 27 depressed patients unmedicated by anti-depressants were enrolled. The diagnosis (depression of moderate degree with somatization) was confirmed by the ICD-10 criteria. 15 age matched normal controls were studied under identical conditions. Baseline and cognition activated 99mTc-ECD SPECT were performed on 21 of the 27 patients with depression and 13 of the 15 normal controls. Baseline 99mTc-ECD SPECT alone were performed on the rest 6 patients with depression and 2 normal controls. The cognitive activation is achieved by Wisconsin Card Sorting Test (WCST). 1110 MBq of 99mTc-ECD was administered by intravenous bolus injection 5 minutes after the onset of the WCST. Semi-quantitative analysis was conducted with the 7th, 8th, 9th, 10th, 11th slices of the transaxial imaging. rCBF ratios of every ROI were calculated using the average tissue activity in the region divided by the maximum activity in the cerebellum. Results: 1) The baseline rCBF of left frontal (0.720) and left temporal lobe (0.720) were decreased significantly in depressed patients comparing with those of the control subjects. 2) The activated rCBF of left frontal lobe (0.719) and left temporal lobe (0.690), left parietal lobe (0.701) were decreased evidently than those of the controls. Conclusions: 1) Hypoperfusions of left frontal and left temporal cortexes were identified in patients with depression. 2) The hypoperfusion of left frontal and left temporal cortexes may be the cause of cognition disorder and depressed mood in patients with depression. 3) Cognition activated brain perfusion imaging is helpful for making a more accurate diagnosis of depression

  12. The Physics Potential of Future Long Baseline Neutrino Oscillation Experiments

    OpenAIRE

    Lindner, M.

    2002-01-01

    We discuss in detail different future long baseline neutrino oscillation setups and we show the remarkable potential for very precise measurements of mass splittings and mixing angles. Furthermore it will be possible to make precise tests of coherent forward scattering and MSW effects, which allow to determine the sign of $\\Delta m^2$. Finally strong limits or measurements of leptonic CP violation will be possible, which is very interesting since it is most likely connected to the baryon asym...

  13. GPS dynamic cycle slip detection and correction with baseline constraint

    Institute of Scientific and Technical Information of China (English)

    Liu Zhenkun; Huang Ahunji

    2009-01-01

    When the cycle slips take place in the attitude determination of a moving platform, the precision of the attitude will be impaired badly. A method of cycle slip detection and correction is proposed, which is suitable to the dynamic measurement using GPS carrier phase: the cycle slips detection is first achieved by triple difference observables, then the cycle slips correction is performed with baseline length constraint. The simulation results show that the proposed method is effective to the dynamic cycle slips problem.

  14. Sterile Neutrino Fits to Short Baseline Neutrino Oscillation Measurements

    CERN Document Server

    Conrad, J M; Karagiorgi, G; Shaevitz, M H; Spitz, J

    2012-01-01

    This paper reviews short baseline oscillation experiments as interpreted within the context of one, two, and three sterile neutrino models associated with additional neutrino mass states in the ~1 eV range. Appearance and disappearance signals and limits are considered. We show that fitting short baseline data sets to a (3+3) model, defined by three active and three sterile neutrinos, results in an overall goodness of fit of 67%, and a compatibility of 90% among all data sets -- to be compared to the compatibility of 0.043% and 13% for a (3+1) and a (3+2) model, respectively. While the (3+3) fit yields the highest quality overall, it still finds inconsistencies with the MiniBooNE appearance data sets; in particular, the global fit fails to account for the observed MiniBooNE low-energy excess. Given the overall improvement, we recommend using the results of (3+2) and (3+3) fits, rather than (3+1) fits, for future neutrino oscillation phenomenology. These results motivate the pursuit of further short baseline e...

  15. The First Very Long Baseline Interferometric SETI Experiment

    CERN Document Server

    Rampadarath, H; Tingay, S J; Trott, C M

    2012-01-01

    The first Search for Extra-Terrestrial Intelligence (SETI) conducted with Very Long Baseline Interferometry (VLBI) is presented. By consideration of the basic principles of interferometry, we show that VLBI is efficient at discriminating between SETI signals and human generated radio frequency interference (RFI). The target for this study was the star Gliese 581, thought to have two planets within its habitable zone. On 2007 June 19, Gliese 581 was observed for 8 hours at 1230-1544 with the Australian Long Baseline Array. The dataset was searched for signals appearing on all interferometer baselines above five times the noise limit. A total of 222 potential SETI signals were detected and by using automated data analysis techniques, were ruled out as originating from the Gliese 581 system. From our results we place an upper limit of 7 MW/Hz on the power output of any isotropic emitter located in the Gliese 581 system, within this frequency range. This study shows that VLBI is ideal for targeted SETI, including...

  16. Removing baseline flame's spectrum by using advanced recovering spectrum techniques.

    Science.gov (United States)

    Arias, Luis; Sbarbaro, Daniel; Torres, Sergio

    2012-09-01

    In this paper, a novel automated algorithm to estimate and remove the continuous baseline from measured flame spectra is proposed. The algorithm estimates the continuous background based on previous information obtained from a learning database of continuous flame spectra. Then, the discontinuous flame emission is calculated by subtracting the estimated continuous baseline from the measured spectrum. The key issue subtending the learning database is that the continuous flame emissions are predominant in the sooty regions, in absence of discontinuous radiation. The proposed algorithm was tested using natural gas and bio-oil flames spectra at different combustion conditions, and the goodness-of-fit coefficient (GFC) quality metric was used to quantify the performance in the estimation process. Additionally, the commonly used first derivative method (FDM) for baseline removing was applied to the same testing spectra in order to compare and to evaluate the proposed technique. The achieved results show that the proposed method is a very attractive tool for designing advanced combustion monitoring strategies of discontinuous emissions. PMID:22945158

  17. Safety Performance of Airborne Separation: Preliminary Baseline Testing

    Science.gov (United States)

    Consiglio, Maria C.; Hoadley, Sherwood T.; Wing, David J.; Baxley, Brian T.

    2007-01-01

    The Safety Performance of Airborne Separation (SPAS) study is a suite of Monte Carlo simulation experiments designed to analyze and quantify safety behavior of airborne separation. This paper presents results of preliminary baseline testing. The preliminary baseline scenario is designed to be very challenging, consisting of randomized routes in generic high-density airspace in which all aircraft are constrained to the same flight level. Sustained traffic density is varied from approximately 3 to 15 aircraft per 10,000 square miles, approximating up to about 5 times today s traffic density in a typical sector. Research at high traffic densities and at multiple flight levels are planned within the next two years. Basic safety metrics for aircraft separation are collected and analyzed. During the progression of experiments, various errors, uncertainties, delays, and other variables potentially impacting system safety will be incrementally introduced to analyze the effect on safety of the individual factors as well as their interaction and collective effect. In this paper we report the results of the first experiment that addresses the preliminary baseline condition tested over a range of traffic densities. Early results at five times the typical traffic density in today s NAS indicate that, under the assumptions of this study, airborne separation can be safely performed. In addition, we report on initial observations from an exploration of four additional factors tested at a single traffic density: broadcast surveillance signal interference, extent of intent sharing, pilot delay, and wind prediction error.

  18. Application of outlier analysis for baseline-free damage diagnosis

    Science.gov (United States)

    Kim, Seung Dae; In, Chi Won; Cronin, Kelly E.; Sohn, Hoon; Harries, Kent

    2006-03-01

    As carbon fiber-reinforced polymer (CFRP) laminates have been widely accepted as valuable materials for retrofitting civil infrastructure systems, an appropriate assessment of bonding conditions between host structures and CFRP laminates becomes a critical issue to guarantee the performance of CFRP strengthened structures. This study attempts to develop a continuous performance monitoring system for CFRP strengthened structures by autonomously inspecting the bonding conditions between the CFRP layers and the host structure. The uniqueness of this study is to develop a new concept and theoretical framework of nondestructive testing (NDT), in which debonding is detected "without using past baseline data." The proposed baseline-free damage diagnosis is achieved in two stages. In the first step, features sensitive to debonding of the CFPR layers but insensitive to loading conditions are extracted based on a concept referred to as a time reversal process. This time reversal process allows extracting damage-sensitive features without direct comparison with past baseline data. Then, a statistical damage classifier will be developed in the second step to make a decision regarding the bonding condition of the CFRP layers. The threshold necessary for decision making will be adaptively determined without predetermined threshold values. Monotonic and fatigue load tests of full-scale CFRP strengthened RC beams are conducted to demonstrate the potential of the proposed reference-free debonding monitoring system.

  19. Baseline Systolic Blood Pressure Response to Exercise Stress Test Can Predict Exercise Indices following Cardiac Rehabilitation Program

    Directory of Open Access Journals (Sweden)

    Akram Sardari

    2010-11-01

    Full Text Available Background: Systolic blood pressure recovery (rSBP is of prognostic value for predicting the survival and co-morbidity rate in patients with coronary artery disease (CAD. This study investigated the association between rSBP and exercise indices after complete cardiac rehabilitation program (CR in a population-based sample of patients undergoing coronary artery bypass grafting (CABG.Methods: The sample population consisted of 352 patients who underwent pure CABG. The patients underwent standard symptom-limited exercise testing immediately before and also after the completion of the CR sessions. rSBP was defined as the ratio of the systolic blood pressure at 3 minutes in recovery to the systolic blood pressure at peak exercise.Results: An abnormal baseline rSBP after exercise was a strong predictor of exercise parameters in the last session, including metabolic equivalents (β = -0.617, SE = 0.127, p value < 0.001 and peak O2 consumption (β = -1.950, SE = 0.363, p value < 0.001 measured in the last session adjusted for baseline exercise characteristics, demographics, function class, and left ventricular ejection fraction.Conclusion: The current study strongly emphasizes the predictive role of baseline rSBP after exercise in evaluating exercise parameters following CR. This baseline index can predict abnormal METs value, peak O2 consumption, post-exercise heart rate, and heart rate recovery after a 24-session CR program.

  20. Re-creating missing population baselines for Pacific reef sharks.

    Science.gov (United States)

    Nadon, Marc O; Baum, Julia K; Williams, Ivor D; McPherson, Jana M; Zgliczynski, Brian J; Richards, Benjamin L; Schroeder, Robert E; Brainard, Russell E

    2012-06-01

    Sharks and other large predators are scarce on most coral reefs, but studies of their historical ecology provide qualitative evidence that predators were once numerous in these ecosystems. Quantifying density of sharks in the absence of humans (baseline) is, however, hindered by a paucity of pertinent time-series data. Recently researchers have used underwater visual surveys, primarily of limited spatial extent or nonstandard design, to infer negative associations between reef shark abundance and human populations. We analyzed data from 1607 towed-diver surveys (>1 ha transects surveyed by observers towed behind a boat) conducted at 46 reefs in the central-western Pacific Ocean, reefs that included some of the world's most pristine coral reefs. Estimates of shark density from towed-diver surveys were substantially lower (sharks observed in towed-diver surveys and human population in models that accounted for the influence of oceanic primary productivity, sea surface temperature, reef area, and reef physical complexity. We used these models to estimate the density of sharks in the absence of humans. Densities of gray reef sharks (Carcharhinus amblyrhynchos), whitetip reef sharks (Triaenodon obesus), and the group "all reef sharks" increased substantially as human population decreased and as primary productivity and minimum sea surface temperature (or reef area, which was highly correlated with temperature) increased. Simulated baseline densities of reef sharks under the absence of humans were 1.1-2.4/ha for the main Hawaiian Islands, 1.2-2.4/ha for inhabited islands of American Samoa, and 0.9-2.1/ha for inhabited islands in the Mariana Archipelago, which suggests that density of reef sharks has declined to 3-10% of baseline levels in these areas. PMID:22536842

  1. A baseline algorithm for face detection and tracking in video

    Science.gov (United States)

    Manohar, Vasant; Soundararajan, Padmanabhan; Korzhova, Valentina; Boonstra, Matthew; Goldgof, Dmitry; Kasturi, Rangachar

    2007-10-01

    Establishing benchmark datasets, performance metrics and baseline algorithms have considerable research significance in gauging the progress in any application domain. These primarily allow both users and developers to compare the performance of various algorithms on a common platform. In our earlier works, we focused on developing performance metrics and establishing a substantial dataset with ground truth for object detection and tracking tasks (text and face) in two video domains -- broadcast news and meetings. In this paper, we present the results of a face detection and tracking algorithm on broadcast news videos with the objective of establishing a baseline performance for this task-domain pair. The detection algorithm uses a statistical approach that was originally developed by Viola and Jones and later extended by Lienhart. The algorithm uses a feature set that is Haar-like and a cascade of boosted decision tree classifiers as a statistical model. In this work, we used the Intel Open Source Computer Vision Library (OpenCV) implementation of the Haar face detection algorithm. The optimal values for the tunable parameters of this implementation were found through an experimental design strategy commonly used in statistical analyses of industrial processes. Tracking was accomplished as continuous detection with the detected objects in two frames mapped using a greedy algorithm based on the distances between the centroids of bounding boxes. Results on the evaluation set containing 50 sequences (~ 2.5 mins.) using the developed performance metrics show good performance of the algorithm reflecting the state-of-the-art which makes it an appropriate choice as the baseline algorithm for the problem.

  2. TWRS phase I privatization site environmental baseline and characterization plan

    International Nuclear Information System (INIS)

    This document provides a plan to characterize and develop an environmental baseline for the TWRS Phase I Privatization Site before construction begins. A site evaluation study selected the former Grout Disposal Area of the Grout Treatment Facility in the 200 East Area as the TWRS Phase I Demonstration Site. The site is generally clean and has not been used for previous activities other than the GTF. A DQO process was used to develop a Sampling and Analysis Plan that would allow comparison of site conditions during operations and after Phase I ends to the presently existing conditions and provide data for the development of a preoperational monitoring plan

  3. Scanner baseliner monitoring and control in high volume manufacturing

    Science.gov (United States)

    Samudrala, Pavan; Chung, Woong Jae; Aung, Nyan; Subramany, Lokesh; Gao, Haiyong; Gomez, Juan-Manuel

    2016-03-01

    We analyze performance of different customized models on baseliner overlay data and demonstrate the reduction in overlay residuals by ~10%. Smart Sampling sets were assessed and compared with the full wafer measurements. We found that performance of the grid can still be maintained by going to one-third of total sampling points, while reducing metrology time by 60%. We also demonstrate the feasibility of achieving time to time matching using scanner fleet manager and thus identify the tool drifts even when the tool monitoring controls are within spec limits. We also explore the scanner feedback constant variation with illumination sources.

  4. Integrated Baseline System (IBS) Version 1.03: Utilities guide

    Energy Technology Data Exchange (ETDEWEB)

    Burford, M.J.; Downing, T.R.; Pottier, M.C.; Schrank, E.E.; Williams, J.R.

    1993-01-01

    The Integrated Baseline System (IBS) is an emergency management planning and analysis tool that was developed under the direction of the Federal Emergency Management Agency (FEMA). This Utilities Guide explains how to operate utility programs that are supplied as a part of the IBS. These utility programs are chiefly for managing and manipulating various kinds of IBS data and system administration files. Many of the utilities are for creating, editing, converting, or displaying map data and other data that are related to geographic location.

  5. Smart Retro: Novel Ways to Develop Cities : Baseline Report

    OpenAIRE

    Neuvonen, Aleksi; Wangel, Josefin; Liljenström, Carolina; Annala, Mikko; Parkkinen, Marjukka; Valladares, Andrea; Mattila, Kalle; Vesanen, Verna

    2014-01-01

    WHAT WILL your home and neighbourhood look like in twenty years? The radical development in smart solutions, the ageing of building stock, our need to radically cut our greenhouse gas emissions and many other strong drivers are changing the way we live, faster than ever before. That change is particularly significant in areas with older building stock – but it is not deterministic change. This is a baseline report for Smart Retro: a project exploring how we can rein in the strength of emergin...

  6. Organic Contamination Baseline Study on NASA JSC Astromaterial Curation Gloveboxes

    Science.gov (United States)

    Calaway, Michael J.; Allton, J. H.; Allen, C. C.; Burkett, P. J.

    2013-01-01

    Future planned sample return missions to carbon-rich asteroids and Mars in the next two decades will require strict handling and curation protocols as well as new procedures for reducing organic contamination. After the Apollo program, astromaterial collections have mainly been concerned with inorganic contamination [1-4]. However, future isolation containment systems for astromaterials, possibly nitrogen enriched gloveboxes, must be able to reduce organic and inorganic cross-contamination. In 2012, a baseline study was orchestrated to establish the current state of organic cleanliness in gloveboxes used by NASA JSC astromaterials curation labs that could be used as a benchmark for future mission designs.

  7. Future long-baseline neutrino oscillations: View from Europe

    International Nuclear Information System (INIS)

    Since about a decade the european physics community interested in neutrino and neutrino-astrophysics develops a plan to conceive the next generation large underground neutrino observatory. Recently, the LAGUNA-LBNO collaboration made the outcome of the FP7 design study public which shows a clear path for the realization of such experiment. In this paper the LAGUNA and LAGUNA-LBNO Design studies, resulting in a proposal for the LBNO experiment, will be discussed. The author will focus on the long baseline neutrino oscillation search, especially on the potential to discover the neutrino mass ordering and the search for CP violation in the lepton sector

  8. Constraints on New Physics from Long Baseline Neutrino Oscillation Experiments

    OpenAIRE

    Honda, Minako; Kao, Yee; Okamura, Naotoshi; Pronin, Alexey; Takeuchi, Tatsu

    2007-01-01

    New physics beyond the Standard Model can lead to extra matter effects on neutrino oscillation if the new interactions distinguish among the three flavors of neutrino. In a previous paper, we argued that a long-baseline neutrino oscillation experiment in which the Fermilab-NUMI beam in its high-energy mode is aimed at the planned Hyper-Kamiokande detector would be capable of constraining the size of those extra effects, provided the vacuum value of \\sin^2 2\\theta_{23} is not too close to one....

  9. Integrated Baseline System (IBS) Version 2.0: Utilities Guide

    Energy Technology Data Exchange (ETDEWEB)

    Burford, M.J.; Downing, T.R.; Williams, J.R. [Pacific Northwest Lab., Richland, WA (United States); Bower, J.C. [Bower Software Services, Kennewick, WA (United States)

    1994-03-01

    The Integrated Baseline System (IBS) is an emergency management planning and analysis tool being developed under the direction of the US Army Nuclear and Chemical Agency. This Utilities Guide explains how you can use the IBS utility programs to manage and manipulate various kinds of IBS data. These programs include utilities for creating, editing, and displaying maps and other data that are referenced to geographic location. The intended audience for this document are chiefly data managers but also system managers and some emergency management planners and analysts.

  10. Emergency Response Capability Baseline Needs Assessment Compliance Assessment

    Energy Technology Data Exchange (ETDEWEB)

    Sharry, John A. [Lawrence Livermore National Lab. (LLNL), Livermore, CA (United States)

    2013-09-16

    This document is the second of a two-part analysis of Emergency Response Capabilities of Lawrence Livermore National Laboratory. The first part, 2013 Baseline Needs Assessment Requirements Document established the minimum performance criteria necessary to meet mandatory requirements. This second part analyses the performance of Lawrence Livermore Laboratory Emergency Management Department to the contents of the Requirements Document. The document was prepared based on an extensive review of information contained in the 2009 BNA, the 2012 BNA document, a review of Emergency Planning Hazards Assessments, a review of building construction, occupancy, fire protection features, dispatch records, LLNL alarm system records, fire department training records, and fire department policies and procedures.

  11. Environmental surveys of the Heidrun field. Supplementary baseline survey 1992

    International Nuclear Information System (INIS)

    The present survey is a re-investigation of the sea bottom sediments at six sites in the Heidrun oil and gas field, May 1992. Petroleum hydrocarbons and heavy metals were at background levels. Compared to the baseline survey in 1988 values of hydrocarbons and barium were decreased. The sediment fauna was sparse with low numbers of species and individuals. Densities were strongly reduced and diversity decreased compared to 1988. There is no indication of anthropogenic factors or other large scale disturbances in the area to explain the faunal changes, which may reflect a large natural variation in the sediment fauna. 22 refs., 16 figs., 35 tabs

  12. Integrated Baseline System (IBS) Version 2.0: Models guide

    Energy Technology Data Exchange (ETDEWEB)

    1994-03-01

    The Integrated Baseline System (IBS) is an emergency management planning and analysis tool being developed under the direction of the US Army Nuclear and Chemical Agency. This Models Guide summarizes the IBS use of several computer models for predicting the results of emergency situations. These include models for predicting dispersion/doses of airborne contaminants, traffic evacuation, explosion effects, heat radiation from a fire, and siren sound transmission. The guide references additional technical documentation on the models when such documentation is available from other sources. The audience for this manual is chiefly emergency management planners and analysts, but also data managers and system managers.

  13. Long baseline accelerator neutrino experiments present and future

    CERN Document Server

    Rubbia, André

    2000-01-01

    A nu /sub mu / disappearance effect has been seen in atmospheric neutrino experiments. This has led to the "evidence for neutrino oscillations". The next problem in neutrino physics is to perform the right experiment(s) to elucidate in a comprehensive way the pattern of neutrino masses and mixings. The long baseline experiments will play a fundamental role at settling definitively the question of flavor oscillation and at measuring with good precision the oscillation parameters. The CERN-NGS beam coupled with the proposed ICANOE and OPERA detectors is the only programme capable of sensitive tau and electron appearance searches. (14 refs).

  14. Postoperative Infection Rates in Patients with a Negative Baseline Urine Culture Undergoing Ureteroscopic Stone Removal

    DEFF Research Database (Denmark)

    Martov, Alexey; Gravas, Stavros; Etemadian, Masoud;

    2015-01-01

    Abstract Purpose: To examine the effects of antibiotic prophylaxis on postoperative infection rate in patients with negative urine cultures undergoing ureteroscopy (URS). Patients and Methods: Using the Clinical Research Office of the Endourological Society (CROES) URS Global Study database...... placement. Patient characteristics, operative data, and postoperative outcomes, including the development of urinary tract infection (UTI) and fever, in the two groups were compared. Results: Antibiotic prophylaxis use differed widely across participating countries (13%-100%). Differences were found between......, patients with a negative baseline urine culture undergoing URS for ureteral stones (n=1141) or kidney stones (n=184) not receiving antibiotic prophylaxis were matched with those who were predefined by risk factors, including gender, American Society of Anesthesiologists (ASA) score, and ureteral stent...

  15. The Full Potential of the Baseline SASE Undulators of the European XFEL

    CERN Document Server

    Agapov, Ilya; Feng, Guangyao; Kocharyan, Vitali; Saldin, Evgeni; Serkez, Svitozar; Zagorodnov, Igor

    2014-01-01

    The output SASE characteristics of the baseline European XFEL, recently used in the TDRs of scientific instruments and X-ray optics, have been previously optimized assuming uniform undulators without considering the potential of undulator tapering in the SASE regime. Here we demonstrate that the performance of European XFEL sources can be significantly improved without additional hardware. The procedure simply consists in the optimization of the undulator gap configuration for each X-ray beamline. Here we provide a comprehensive description of the soft X-ray photon beam properties as a function of wavelength and bunch charge. Based on nominal parameters for the electron beam, we demonstrate that undulator tapering allows one to achieve up to a tenfold increase in peak power and photon spectral density in the conventional SASE regime. We illustrate this fact for the SASE3 beamline. The FEL code Genesis has been extensively used for these studies. Based on these findings we suggest that the requirements for the...

  16. Study on the Neutrino Oscillation with a Next Generation Medium-Baseline Reactor Experiment

    International Nuclear Information System (INIS)

    For over fifty years, reactor experiments have played an important role in neutrino physics, in both discoveries and precision measurements. One of the methods to verify the existence of neutrino is the observation of neutrino oscillation phenomena. Electron antineutrinos emitted from a reactor provide the measurement of the small mixing angle θ13, providing rich programs of neutrino properties, detector development, nuclear monitoring, and application. Using reactor neutrinos, future reactor neutrino experiments, more precise measurements of θ12,Δm122, and mass hierarchy will be explored. The precise measurement of θ13 would be crucial for measuring the CP violation parameters at accelerators. Therefore, reactor neutrino physics will assist in the complete understanding of the fundamental nature and implications of neutrino masses and mixing. In this paper, we investigated several characteristics of RENO-50, which is a future medium-baseline reactor neutrino oscillation experiment, by using the GloBES simulation package

  17. Relationship status and relationship instability, but not dominance, predict individual differences in baseline cortisol levels.

    Directory of Open Access Journals (Sweden)

    Dario Maestripieri

    Full Text Available We investigated variation in baseline cortisol levels in relation to relationship status (single or in a relationship, relationship characteristics (length, stability, presence or absence of clear dominance, or individual attributes (dominant or subordinate status, relative physical attractiveness, relationship worries. Study participants were 77 men and 75 women aged between 18 and 38 years. Individuals in romantic relationships had lower cortisol levels than singles. Individuals of African ethnicity, however, showed the opposite pattern. Individuals who perceived their relationship to be highly unstable had higher cortisol levels. Aside from African-Americans, married individuals reported the lowest relationship instability and the lowest cortisol levels, followed by individuals in long-term relationships, and by individuals in short-term relationships. The presence or absence of clear dominance in the relationship, dominance status, or relationship worries did not affect cortisol levels. Therefore relationship status and relationship instability were better predictors of variation in cortisol (presumably through stress-related mechanisms than individual attributes.

  18. Development of A Prototype Short Baseline Detector for Antineutrinos from the HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Jeon, Eunju; Kim, Jinyu; Kim, Yeongduk [KAERI, Daejeon (Korea, Republic of); and others

    2013-05-15

    The neutrons then cause more fissions, and the daughter nuclei decay emitting an antineutrino with each decay. Because neutrino can penetrate every thick matters composed of heavy concrete, lead and metals and so on, it is considered to be a promising monitoring probe for civil nuclear facilities and nuclear inventories. In fission process of the reactor core, uranium-235 produces antineutrinos in greater abundance than plutonium-239 over a certain energy range. As burnup proceeds, the neutrino energy spectrum deviates from an initial one. Recent report published by the Department of Safeguards of IAEA also said that a short baseline (SBL) neutrino detector has an intrinsic characteristics for monitoring status, operation power, nuclear fuel composition ratio in real time outside the containment building of the nuclear reactor with no-interference mode. Since KamLAND experiments in 2002 gave a precise observation, neutrino flavor oscillation model has been accepted to be an actual phenomenon. One of interesting issues on the reactor neutrino is an anomaly that number of measured neutrinos shows a deficit of 6% comparing with the expectation, which means that there should be an undetected sterile neutrino in addition to the known three flavors. It should be created in the flavor oscillations and does not participate in a weak interaction. The recent high precision and high statistics data from Double Chooz, Daya Bay and RENO experiments may imply it. This research develops a short baseline neutrino detector and the technology for reactor monitoring by measuring precisely the neutrino energy spectrum with a detector located close to the HANARO research reactor. Also it will develop a liquid scintillator containing metals which has large neutron capture cross section, and pulse shape discrimination methods, then we will have a more flexible technology which can detect reactor neutrinos at overground. Reactor antineutrino experiment is under preparation for the

  19. From groundwater baselines to numerical groundwater flow modelling for the Milan metropolitan area

    Science.gov (United States)

    Crosta, Giovanni B.; Frattini, Paolo; Peretti, Lidia; Villa, Federica; Gorla, Maurizio

    2015-04-01

    Contamination of major aquifers in highly densely populated areas is a major concern for stakeholders involved in the use and protection of groundwater resources. Sustainable groundwater withdrawal and management, and the identification of trends in groundwater contamination require a careful hydrochemical baseline characterization. This characterization is fundamental to investigate the presence and evolutionary trend of contaminants. In fact, it allows recovering and understanding: the spatial-temporal trend of contamination; the relative age of the contamination episodes; the reasons for anomalous behavior of some compounds during migration to and in the groundwater; the associations with which some contaminants can be found; the different behaviors in phreatic and semi-confined and confined aquifers. To attain such a characterization for the Milan metropolitan area (about 2,500 km2, ca 4.000.000 inhabitants, Lombardy, Italy), we carried out three main activities. (1) Collection of complete and reliable datasets concerning the geological, hydrogeological and hydrochemical (over 60,000 chemical analysis since 2003 to 2013) characteristics of the area and of the involved aquifers. This activity was very demanding because the available data are provided by different authorities (Lombardy Region, Provinces, Lombardy Environmental Agency - ARPA Lombardia, public own companies in charge of water system managements) in raw format and with different database standard, which required a large effort of manual verification and harmonization. (2) Completion of a hydrochemical characterization of the metropolitan area aquifers by classical statistical and multivariate statistical analyses, in order to define a baseline both for some major physical chemical characteristics and for the most relevant contaminants. (3) Development of a three dimensional hydrogeological model for the metropolitan area starting from the above listed datasets and existing models. This model will

  20. Baseline characterization of electrical circuits to support plant life extension

    International Nuclear Information System (INIS)

    To (a) provide data on the relative condition of certain electrical cable in use on one of its nuclear plants, and (b) gain experience with state-of-the-art equipment and procedures for obtaining these data under the US Department of Energy (DOE) technology transfer to industry program, Southern California Edison Company (SCE) performed a program in association with EG and G Idaho, Inc., at the San Onofre Nuclear Generating Station (SONGS), Unit 1 during the Cycle IX Refueling Outage in April and May 1986. The program obtained baseline data for characterization of electrical circuits utilizing the Electrical Circuit Characterization and Diagnostic (ECCAD) System, developed by EG and G Idaho, Inc. under contract to the DOE. The ECCAD system and the SONGS 1 program to utilize it are described to show a method for characterizing electrical circuits by comparison to baseline data or to data from similar circuits. This demonstrates a capability to identify the effects of environment and aging on electrical circuits. This technique was shown to have both short-term (diagnostic) potential and long-term (characterizing aging effects) potential for use in applications where electrical circuits may be subjected to environmental conditions that can lead to cable degradation

  1. EMD-based GPS baseline solution and validation test

    Institute of Scientific and Technical Information of China (English)

    WANG Jian; GAO Jing-xiang; WANG Jin-ling; XU Chang-hui

    2008-01-01

    A GPS baseline solution model is presented, based on the Empirical Mode Decomposition (EMD), which has the advantage of eliminating the error effects outside the model. The EMD technique is a new signal processing method for non-linear time series, which decomposes a time series into a finite and often small number of Intrinsic Mode Functions (IMFs). The decomposition procedure is adaptive and data-driven which is suitable for non-linear data series analysis. A multi-scale decomposition and reconstruction architecture is defined on the basis of the EMD theory and the error mitigation model is demonstrated as well. A standard of the scale selection for the elimination of errors, outside the model, was given in terms of the mean of the accumulated standardized modes. Thereafter, the scheme of the GPS baseline solution based on the EMD is suggested. The float solution residuals of the Double-Difference (DD) observation equation are used to extract the errors outside the model applied to modify the GPS DD measurements. Then the float solution was given again and the fixed solution was obtained by a Lambda algorithm. Three schemes are designed to test the proposed model and the experimental results show that the proposed model dramatically improves the relia- bility of ambiguity resolution after the elimination of errors outside the model.

  2. Eielson Air Force Base OU-1 baseline risk assessment

    International Nuclear Information System (INIS)

    This Baseline Risk Assessment report is the second volume in a set of three volumes for operable Unit 1 (OU-1). The companion documents contain the Remedial Investigation and the Feasibility Study. Operable Unit 1 (OU-1) is one of several groups of hazardous waste sites located at Eielson Air Force Base (AFB) near Fairbanks, Alaska. The operable units at Eielson are typically characterized by petroleum, oil, lubricant/solvent contamination, and by the presence of organics floating at the water table. In 1989 and 1990, firms under contract to the Air Force conducted field studies to gather information about the extent of chemical contamination in soil, groundwater, and soil air pore space (soil gas) at the site. This report documents the results of a baseline risk assessment, which uses the 1989 and 1991 site characterization database to quantify the potential human health risk associated with past Base industrial activities in the vicinity of OU-1. Background data collected in 1992 were also used in the preparation of this report

  3. On the baseline evolution of automobile fuel economy in Europe

    International Nuclear Information System (INIS)

    'Business as usual' scenarios in long-term energy forecasts are crucial for scenario-based policy analyses. This article focuses on fuel economy of passenger cars and light trucks, a long-disputed issue with serious implications for worldwide energy use and CO2 emissions. The current status in Europe is explained and future developments are analysed with the aid of historical data of the last three decades from the United States and Europe. As a result of this analysis, fuel economy values are proposed for use as assumptions in baseline energy/transport scenarios in the 15 'old' European Union Member States. Proposed values are given for new gasoline and diesel cars and for the years 2010, 2020 and 2030. The increasing discrepancy between vehicle fuel consumption measured under test conditions and that in the real world is also considered. One main conclusion is that the European Commission's voluntary agreement with the automobile industry should not be assumed to fully achieve its target under baseline conditions, nor should it be regarded as a major stimulus for autonomous vehicle efficiency improvements after 2010. A second conclusion is that three very recent studies enjoying authority across the EU tend to be overly optimistic as regards the technical progress for conventional and alternative vehicle propulsion technologies under 'business as usual' conditions

  4. Baseline Gas Turbine Development Program sixth quarterly progress report

    Energy Technology Data Exchange (ETDEWEB)

    Wagner, C.E.

    1974-04-30

    Progress is reported for a program to demonstrate by 1976 an experimental gas turbine powered automobile which meets the 1976 Federal Emissions Standards, has significantly improved fuel economy, and is competitive in performance, reliability, and potential manufacturing cost with the conventional piston engine powered, standard size American automobile. Engines were built to replace those originally loaned to the Program. Efforts to identify and correct a general power deficiency were generally successful. The third baseline vehicle was built and checked out. Baseline vehicle emissions, performance, fuel consumption, and noise tests were run. Chrysler's proprietary linerless insulation showed no significant distress following 300 hours of engine endurance testing. An improved elastomeric drive for ceramic regenerators was developed on the regenerator rig. Preparations are being made for engine testing. The Ai Research engine simulation model is operational and control system concepts are being studied. Operation of the preprototype fuel system was verified on an engine. All other key preprototype system elements were bench checked. Variable inlet guide vane testing and development and torque converter lock-up evaluation tests are in process. A free rotor engine arrangement for vehicle evaluation and development is being built. Initial specifications were completed for a 122 horsepower, compact vehicle upgraded engine. NASA completed initial specifications for the gas generator aerodynamics. Overall engine and engine housing layout studies are being made.

  5. Predictors of a positive baseline bone scan in breast cancer

    International Nuclear Information System (INIS)

    The aim of this retrospective study was to determine the predictors of a positive bone scan in female patients with breast carcinoma. The participants were 126 females with newly diagnosed breast carcinoma and a baseline bone scan. Patients who had started treatment before their bone scan were excluded. Bone scans were assessed as 'no metastases' or 'definite skeletal metastases' without knowledge of the patient's predictor variables. Those with 'possible metastases' were correlated with other available imaging and clinical information, and re-categorised as 'no metastases' or 'definite skeletal metastases'. Results were compared with predictor variables. Significant predictors were increasing age, a higher histopathological grading and positive progesterone receptor status following a forward-stepwise logistic regression analysis. Axillary nodal status, tumour size and oestrogen receptor status did not correlate with a positive bone scan. Not every patient needs a staging bone scan. This study is important because it predicts the need for baseline scintigraphy for specific patients in whom skeletal metastases are more likely to be present or to develop. The findings are particularly valuable in times of worldwide resource scarcity and evolving surgical practice. Copyright (2005) Blackwell Publishing Asia Pty Ltd

  6. Does Baseline Heart Rate Variability Reflect Stable Positive Emotionality?

    Science.gov (United States)

    Silvia, Paul J; Jackson, Bryonna A; Sopko, Rachel S

    2014-11-01

    Several recent studies have found significant correlations, medium in effect size, between baseline heart rate variability (HRV) and measures of positive functioning, such as extraversion, agreeableness, and trait positive affectivity. Other research, however, has suggested an optimal level of HRV and found nonlinear effects. In the present study, a diverse sample of 239 young adults completed a wide range of measures that reflect positive psychological functioning, including personality traits, an array of positive emotions (measured with the Dispositional Positive Emotions Scale), and depression, anxiety, and stress symptoms (measured with the DASS and CESD). HRV was measured with a 6-minute baseline period and quantified using many common HRV metrics (e.g., respiratory sinus arrhythmia, root mean square of successive differences, and others), and potentially confounding behavioral and lifestyle variables (e.g., BMI, caffeine and nicotine use, sleep quality) were assessed. Neither linear nor non-linear effects were found, and the effect sizes were small and near zero. The findings suggest that the cross-sectional relationship between HRV and positive experience deserves more attention and meta-analytic synthesis. PMID:25147421

  7. On the baseline evolution of automobile fuel economy in Europe

    Energy Technology Data Exchange (ETDEWEB)

    Zachariadis, Theodoros [Economics Research Centre, University of Cyprus, P.O. Box 20537, 1678 Nicosia (Cyprus)]. E-mail: zach@hol.gr

    2006-09-15

    'Business as usual' scenarios in long-term energy forecasts are crucial for scenario-based policy analyses. This article focuses on fuel economy of passenger cars and light trucks, a long-disputed issue with serious implications for worldwide energy use and CO{sub 2} emissions. The current status in Europe is explained and future developments are analysed with the aid of historical data of the last three decades from the United States and Europe. As a result of this analysis, fuel economy values are proposed for use as assumptions in baseline energy/transport scenarios in the 15 'old' European Union Member States. Proposed values are given for new gasoline and diesel cars and for the years 2010, 2020 and 2030. The increasing discrepancy between vehicle fuel consumption measured under test conditions and that in the real world is also considered. One main conclusion is that the European Commission's voluntary agreement with the automobile industry should not be assumed to fully achieve its target under baseline conditions, nor should it be regarded as a major stimulus for autonomous vehicle efficiency improvements after 2010. A second conclusion is that three very recent studies enjoying authority across the EU tend to be overly optimistic as regards the technical progress for conventional and alternative vehicle propulsion technologies under 'business as usual' conditions.

  8. Model Order Selection in Multi-baseline Interferometric Radar Systems

    Directory of Open Access Journals (Sweden)

    Fulvio Gini

    2005-12-01

    Full Text Available Synthetic aperture radar interferometry (InSAR is a powerful technique to derive three-dimensional terrain images. Interest is growing in exploiting the advanced multi-baseline mode of InSAR to solve layover effects from complex orography, which generate reception of unexpected multicomponent signals that degrade imagery of both terrain radar reflectivity and height. This work addresses a few problems related to the implementation into interferometric processing of nonlinear algorithms for estimating the number of signal components, including a system trade-off analysis. Performance of various eigenvalues-based information-theoretic criteria (ITC algorithms is numerically investigated under some realistic conditions. In particular, speckle effects from surface and volume scattering are taken into account as multiplicative noise in the signal model. Robustness to leakage of signal power into the noise eigenvalues and operation with a small number of looks are investigated. The issue of baseline optimization for detection is also addressed. The use of diagonally loaded ITC methods is then proposed as a tool for robust operation in the presence of speckle decorrelation. Finally, case studies of a nonuniform array are studied and recommendations for a proper combination of ITC methods and system configuration are given.

  9. Elevating Baseline Activation Does Not Facilitate Reading of Unattended Words

    Science.gov (United States)

    Lien, Mei-Ching; Kouchi, Scott; Ruthruff, Eric; Lachter, Joel B.

    2009-01-01

    Previous studies have disagreed the extent to which people extract meaning from words presented outside the focus of spatial attention. The present study, examined a possible explanation for such discrepancies, inspired by attenuation theory: unattended words can be read more automatically when they have a high baseline level of activation (e.g., due to frequent repetition or due to being expected in a given context). We presented a brief prime word in lowercase, followed by a target word in uppercase. Participants indicated whether the target word belonged to a particular category (e.g., "sport"). When we drew attention to the prime word using a visual cue, the prime produced substantial priming effects on target responses (i.e., faster responses when the prime and target words were identical or from the same category than when they belonged to different categories). When prime words were not attended, however, they produced no priming effects. This finding replicated even when there were only 4 words, each repeated 160 times during the experiment. Even with a very high baseline level of activation, it appears that very little word processing is possible without spatial attention.

  10. U Plant Aggregate Area Management study technical baseline report

    International Nuclear Information System (INIS)

    This document was prepared in support of an Aggregate Area Management Study of U Plant. It provides a technical baseline of the aggregate area and results from an environmental investigation that was undertaken by the Technical Baseline Section of the Environmental Engineering Group, Westinghouse Hanford Company (WHC), which is currently the Waste Site and Facility Research Office, Natural Resources, Bechtel Hanford, Inc. (BHI). It is based upon review and evaluation of numerous Hanford Site current and historical reports, drawings and photographs, supplemented with site inspections and employee interviews. U Plant refers to the 221-U Process Canyon Building, a chemical separation facility constructed during World War II. It also includes the Uranium Oxide (UO3) Plant constructed at the same time as 221-U as an adjunct to the original plutonium separation process but which, like 221-U, was converted for other missions. Waste sites are associated primarily with U Plant's 1952 through 1958 Uranium Metal Recovery Program mission and the U03 Plant's ongoing U03 mission. Waste sites include cribs, reverse wells, french drains, septic tanks and drain fields, trenches, catch tanks, settling tanks, diversion boxes, a waste vault, and the lines and encasements that connect them. It also includes the U Pond and its feed ditches and an underground tank farm designed for high-level liquid wastes

  11. DGEMP-OE (2008) Energy Baseline Scenario. Synthesis report

    International Nuclear Information System (INIS)

    A 'Business as usual' or 'Baseline' scenario of energy trends to 2020-2030 is produced by France every four years, as requested by the International Energy Agency in order to update the global scenarios published in its World Energy Outlook. Since the most recent scenario of this type was drawn up in 2003-2004, the time has come to renew the effort for the IEA's next in-depth review of French energy policy. Specifically, the DGEMP seeks to predict the future of France's energy situation assuming that no policies or new measures are taken affecting (i.e. improving or deteriorating) the situation other than those already in place or adopted as of 1 January 2008 (in other words, before measures such as those stemming from the Grenelle Environment Forum). On the other hand, it is assumed that change in the energy system is guided by 'conventional wisdom' according to which political options and behaviours by economic units are expected to be 'reasonable'. As a result, even should its projections prove inappropriate, this cannot be considered a 'worst-case' scenario. Indeed, beyond the IEA, this scenario can be used to establish an MEA (Multilateral Environment Agreement) scenario (based on existing measures) for national communications submitted under the U.N. Climate Convention. The scenarios by the 'Energy' Commission, part of the Centre d'Analyse Strategique (CAS), could have been used, particularly since the consultant who worked with the CAS to develop its scenarios was also commissioned by the DGEMP. However, several considerations argued in favour of proceeding separately: - The CAS scenarios drew on the DGEMP's 2004 baseline scenario, even though certain parameters were updated (in particular energy prices). - Moreover, the concept underpinning the DGEMP baseline scenario is that it should to every extent possible remain constant over time to secure continued consensus on this 'reference' at national level. - Finally, the MEDEE energy demand model applied in

  12. Estimating baseline carbon emissions for the Eastern Panama Canal watershed

    Energy Technology Data Exchange (ETDEWEB)

    Dale, V.H. [Environmental Sciences Division, Oak Ridge National Laboratory, Oak Ridge, TN 37831-6036 (United States); Brown, S. [Ecosystem Services Unit, Winrock International, 1621 N Kent St, Suite 1200, Arlington, VA 22209 (United States); Calderon, M.O.; Montoya, A.S.; Martinez, R.E. [Remote Sensing Unit of the Panama Canal Watershed, Panama Canal Authority, Panama City (Panama)

    2003-07-01

    To participate in the potential market for carbon credits based on changes in the use and management of the land, one needs to identify opportunities and implement land-use based emissions reductions or sequestration projects. A key requirement of land-based carbon (C) projects is that any activity developed for generating C benefits must be additional to business-as-usual. A rule-based model was developed and used that estimates changes in land-use and subsequent carbon emissions over the next twenty years using the Eastern Panama Canal Watershed (EPCW) as a case study. These projections of changes in C stocks serve as a baseline to identify where opportunities exist for implementing projects to generate potential C credits and to position Panama to be able to participate in the emerging C market by developing a baseline under scenarios of business-as-usual and new-road development. The projections show that the highest percent change in land use for the new-road scenario compared to the business-as-usual scenario is for urban areas, and the greatest cause of C emission is from deforestation. Thus, the most effective way to reduce C emissions to the atmosphere in the EPCW is by reducing deforestation. In addition to affecting C emissions, reducing deforestation would also protect the soil and water resources of the EPCW. Yet, under the current framework of the Clean Development Mechanism (CDM), only credits arising from reforestation are allowed, which after 20 years of plantation establishment are not enough to offset the C emissions from the ongoing, albeit small, rate of deforestation in the EPCW. The study demonstrates the value of spatial regional projections of changes in land cover and C stocks: The approach helps a country identify its potential greenhouse gas (GHG) emission liabilities into the future and provides opportunity for the country to plan alternative development pathways; It could be used by potential project developers to identify which types

  13. Efeitos do consumo prévio de carboidratos sobre a resposta glicêmica e desempenho Efectos del consumo previo de carbohidratos sobre la respuesta de glicemia y desempeño Effect of prior consumption of carbohydrate on the glycaemia and performance

    Directory of Open Access Journals (Sweden)

    Katiuce Borges Sapata

    2006-08-01

    ocasionó alteraciones en la glicemia y en la frecuencia cardiaca durante el ejercicio. Aunque se especule que oscilaciones en la glicemia durante el ejercicio puedan perjudicar el desempeño en ejercicios de larga duración, este hecho no fue verificado en nuestro presente estudio.BASES AND OBJECTIVE: Nutrition is an important tool for the sport practice. Among the nutrients, the carbohydrates are one of the most important. In that way the aim of this study was analyze the influence of glycaemic response on performance of healthy subjects, after intake of different carbohydrate solutions. METHODS: Ten healthy male subjects, 23 ± 2.1 years old, were asked to answer a three days nutritional and physical activity recordatory. Anthropometric data were collected and a progressive test in cycle ergometer was performed to measure the maximal oxygen uptake and ventilatory thresholds. Each subject performed three submaximal tests at the intensity of second ventilatory threshold. Thirty minutes before each submaximal test, 250 ml of each drink: maltodextrin (Malto, glucose (Glicose plus sport drink or dietetic juice (Placebo was ingested. Venous blood was collected to determine the glycaemic index and lactate. RESULTS AND CONCLUSION: There was a significant increase after 30 minutes when the subjects ingested maltodextrin solution (87.4 ± 11.2 to 116.9 ± 19.6 ml.dl¹. After 15 minutes of exercise, there was a decrease in the glycaemia after the consumption of Malto (116.9 ± 19.6 to 77.6 ± 14.5 ml.dl¹ and Glicose (113.2 ± 23.5 to 81.8 ± 13.1 ml.dl¹ plus sport drink solutions when compared with Placebo solution. The glucose plus sport drink solution induced a significant increase in the heart rate during exercise (167.7 ± 14.2 and 177.1 ± 10.4 bpm. The consumption of different carbohydrate solutions with high glycaemic index before exercise was not capable to change the performance of the volunteers. However it induced changes in the glycaemia and heart rate during

  14. Contaminants in ATCA baselines with shadowing: a case study of cross talk in short-spacing interferometers

    CERN Document Server

    Subramanian, R; Subrahmanyan, Ravi; Deshpande, Avinash A.

    2004-01-01

    Interferometric telescopes made of close-packed antenna elements are an important tool for imaging extended radio sources, specifically structures that have angular sizes comparable to or even greater than the FWHM of the beams of the antennas. They have proved useful in observations of cosmic microwave background anisotropies that require high brightness-sensitivity. However, the visibilities measured in baselines formed between close antenna elements -- in particular, between shadowed elements -- of Fourier-synthesis arrays are often observed to be corrupted. We discuss the multiplicative and additive errors affecting such short-baseline interferometers. As a case study, we have examined the nature of the spurious correlations between the Cassegrain-type paraboloidal reflectors that are elements of the Australia Telescope Compact Array. In configurations with geometric shadowing, the cross talk here appears as an additive component. Analysis of the characteristics of this cross talk leads us to believe that...

  15. OCRWM procedure for reporting software baseline change information

    International Nuclear Information System (INIS)

    The purpose of this procedure is to establish a requirement and method for participant organizations to report software baseline change information to the M ampersand O Configuration Management (CM) organization for inclusion in the OCRWM Configuration Information System (CIS). (The requirements for performing software configuration management (SCM) are found in the OCRWM Quality Assurance Requirements and Description (QARD) document and in applicable DOE orders, and not in this procedure.) This procedure provides a linkage between each participant's SCM system and the CIS, which may be accessed for identification, descriptive, and contact information pertaining to software released by a participant. Such information from the CIS will enable retrieval of details and copies of software code and documentation from the participant SCM system

  16. C-018H Pre-Operational Baseline Sampling Plan

    International Nuclear Information System (INIS)

    The objective of this task is to field characterize and sample the soil at selected locations along the proposed effluent line routes for Project C-018H. The overall purpose of this effort is to meet the proposed plan to discontinue the disposal of contaminated liquids into the Hanford soil column as described by DOE (1987). Detailed information describing proposed transport pipeline route and associated Kaiser Engineers Hanford Company (KEH) preliminary drawings (H288746...755) all inclusive, have been prepared by KEH (1992). The information developed from field monitoring and sampling will be utilized to characterize surface and subsurface soil along the proposed C-018H effluent pipeline and it's associated facilities. Potentially existing contaminant levels may be encountered therefore, soil characterization will provide a construction preoperational baseline reference, develop personnel safety requirements, and determine the need for any changes in the proposed routes prior to construction of the pipeline

  17. Edge stability analysis of ITER baseline plasma simulations

    International Nuclear Information System (INIS)

    A stability analysis using equilibria from CORSICA transport simulations finds that the maximum stable pedestal pressure in ITER 15 MA baseline plasma is 110 kPa corresponding to a pedestal temperature of 5.9 keV. The height of the stable pedestal is robust for the assumption of the pedestal height varying only by about 10% if the width of the pedestal is varied by 30%. A conducting first wall has a stabilizing effect on the peeling–ballooning modes that limit the edge pressure. However, the stabilization is unlikely to significantly change the stability limits, but could affect the ELM dynamics by lowering the growth rate of the ELM triggering peeling–ballooning modes. The entire pedestal region is stable against n = ∞ ballooning modes for all studied pedestal temperatures. This is due to the high bootstrap current keeping the magnetic shear in the region of large pressure gradient. (paper)

  18. Baseline Requirements and Architecture for Cloud Computing Services

    Directory of Open Access Journals (Sweden)

    Abdur Rahim Choudhary

    2012-12-01

    Full Text Available Government initiatives such as the “Cloud First” policy are bringing the cloud computing services into Federal Agencies. Further, many of the sectors in the Critical Infrastructure of the nation already use cloud computing. Although cloud computing services are slowly coming to age, many issues remain. This paper therefore takes a closer look at the cloud computing services. First it establishes a baseline by specifying high level requirements for cloud computing services. Next it improves upon the current architecture for the cloud computing services by adding new modules to the current architecture. The new modules are gleaned from an analysis of the telecommunications cloud and security in distributed systems. The new modules include a management and control network, a set of trust domains, and a set of proxies. The improved architecture is more ready for primetime use and supports a richer operational model.

  19. Short-baseline neutrino oscillations, Planck, and IceCube

    CERN Document Server

    Cherry, John F; Shoemaker, Ian M

    2016-01-01

    We examine a framework with light new physics, which couples to the Standard Model only via neutrino mixing. Taking the hints from the short-baseline anomalies seriously and combining them with modern cosmological data and recent IceCube measurements, we obtain surprisingly effective constraints on the hidden force: keV $\\lesssim M \\lesssim0.3$ GeV for the mediator mass and $g_{h}>10^{-6}-10^{-3}$ for the coupling constant. Flavor equilibration between the hidden and active neutrinos can be delayed until temperatures of $\\sim 1$ MeV, but not below $\\sim 100$ keV. This scenario can be tested with next-generation Cosmic Microwave Background, IceCube, and oscillation experiments.

  20. Sandia National Laboratories, California proposed CREATE facility environmental baseline survey.

    Energy Technology Data Exchange (ETDEWEB)

    Catechis, Christopher Spyros

    2013-10-01

    Sandia National Laboratories, Environmental Programs completed an environmental baseline survey (EBS) of 12.6 acres located at Sandia National Laboratories/California (SNL/CA) in support of the proposed Collaboration in Research and Engineering for Advanced Technology and Education (CREATE) Facility. The survey area is comprised of several parcels of land within SNL/CA, County of Alameda, California. The survey area is located within T 3S, R 2E, Section 13. The purpose of this EBS is to document the nature, magnitude, and extent of any environmental contamination of the property; identify potential environmental contamination liabilities associated with the property; develop sufficient information to assess the health and safety risks; and ensure adequate protection for human health and the environment related to a specific property.

  1. Probing light sterile neutrinos in medium baseline reactor experiments

    CERN Document Server

    Esmaili, Arman; Peres, O L G; Tabrizi, Zahra

    2013-01-01

    Medium baseline reactor experiments (Double Chooz, Daya Bay and RENO) provide a unique opportunity to test the presence of light sterile neutrinos. We analyze the data of these experiments in the search of sterile neutrinos and also test the robustness of theta_13 determination in the presence of sterile neutrinos. We show that existence of a light sterile neutrino state improves the fit to these data moderately. We also show that the measured value of theta_{13} by these experiments is reliable even in the presence of sterile neutrinos, and the reliability owes significantly to the Daya Bay and RENO data. From the combined analysis of the data of these experiments we constrain the mixing of a sterile neutrino with mass squared difference in the range of (10^{-3}-10^{-1}) eV^2 to sin^2 2 theta_{14} <0.1 at 95 % C.L..

  2. Report of the US long baseline neutrino experiment study

    CERN Document Server

    Barger, V; Bogert, D; Bromberg, C; Curioni, A; Dierckxsens, M; Diwan, M; Dufour, F; Finley, D; Fleming, B T; Gallardo, J; Heim, J; Huber, P; Jung, C K; Kahn, S; Kearns, E; Kirk, H; Kirk, T; Lande, K; Laughton, C; Lee, W Y; Lesko, K; Lewis, C; Litchfield, P J; Mann, A K; Marchionni, A; Marciano, W; Marfatia, D; Marino, A D; Marshak, M; Menary, S; McDonald, K; Messier, M; Pariseau, W; Parsa, Z; Pordes, S; Potenza, R; Rameika, R; Saoulidou, N; Simos, N; Van Berg, R; Viren, B; Whisnant, K; Wilson, R; Winter, W; Yanagisawa, C; Yumiceva, F; Zimmerman, E D; Zwaska, R

    2007-01-01

    This report provides the results of an extensive and important study of the potential for a U.S. scientific program that will extend our knowledge of neutrino oscillations well beyond what can be anticipated from ongoing and planned experiments worldwide. The program examined here has the potential to provide the U.S. particle physics community with world leading experimental capability in this intensely interesting and active field of fundamental research. Furthermore, this capability could be unique compared to anywhere else in the world because of the available beam intensity and baseline distances. The present study was initially commissioned in April 2006 by top research officers of Brookhaven National Laboratory and Fermi National Accelerator Laboratory and, as the study evolved, it also provided responses to questions formulated and addressed to the study group by the Neutrino Scientific Advisory Committee (NuSAG) of the U.S. DOE and NSF. The participants in the study, its Charge and history, plus the ...

  3. Baseline projections of transportation energy consumption by mode: 1981 update

    Energy Technology Data Exchange (ETDEWEB)

    Millar, M; Bunch, J; Vyas, A; Kaplan, M; Knorr, R; Mendiratta, V; Saricks, C

    1982-04-01

    A comprehensive set of activity and energy-demand projections for each of the major transportation modes and submodes is presented. Projections are developed for a business-as-usual scenario, which provides a benchmark for assessing the effects of potential conservation strategies. This baseline scenario assumes a continuation of present trends, including fuel-efficiency improvements likely to result from current efforts of vehicle manufacturers. Because of anticipated changes in fuel efficiency, fuel price, modal shifts, and a lower-than-historic rate of economic growth, projected growth rates in transportation activity and energy consumption depart from historic patterns. The text discusses the factors responsible for this departure, documents the assumptions and methodologies used to develop the modal projections, and compares the projections with other efforts.

  4. Design studies for a long base-line neutrino beam

    CERN Document Server

    Ball, A E; Vassilopoulos, N

    1995-01-01

    Strong interest has recently been shown in very long base-line neutrino beams, directed at existing or planned massive detector facilities, in order to extend the search for neutrino oscillations. Among such possibilities are beams from CERN pointing towards the Gran Sasso Underground Laboratory in the Ionian Sea off the west coast of the Peloponnese. In order to establish the basic parameters, a number of possible configurations for such beams have been studies covering a range of neutrino energy bands, estimates of the neutrino fluxes, event rates and backgrounds at typical detectors are reported. Considerations have been gioven to the optimum lenght and radius of the decay tunnels. It is shown that with one year of operation, a neutrino oscillation search down to limits of sin2 Ø = 0.01 and m2 = 0.001eV2 could be made with currently proposed detectors.

  5. LTC American's, Inc. vacuum blasting machine: Baseline report

    International Nuclear Information System (INIS)

    The LTC shot blast technology was tested and is being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU's evaluation of efficiency and cost, this report covers the evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The LTC 1073 Vacuum Blasting Machine uses a high-capacity, direct-pressure blasting system which incorporates a continuous feed for the blast media. The blast media cleans the surface within the contained brush area of the blast. It incorporates a vacuum system which removes dust and debris from the surface as it is blasted. The safety and health evaluation during the testing focused on two main areas of exposure: dust and noise

  6. Waste Assessment Baseline for the IPOC Second Floor, West Wing

    Energy Technology Data Exchange (ETDEWEB)

    McCord, Samuel A [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States). Waste Management and Pollution Prevention

    2015-04-01

    Following a building-wide waste assessment in September, 2014, and subsequent presentation to Sandia leadership regarding the goal of Zero Waste by 2025, the occupants of the IPOC Second Floor, West Wing contacted the Materials Sustainability and Pollution Prevention (MSP2) team to guide them to Zero Waste in advance of the rest of the site. The occupants are from Center 3600, Public Relations and Communications , and Center 800, Independent Audit, Ethics and Business Conduct . To accomplish this, MSP2 conducted a new limited waste assessment from March 2-6, 2015 to compare the second floor, west wing to the building as a whole. The assessment also serves as a baseline with which to mark improvements in diversion in approximately 6 months.

  7. Updated results of the OPERA long baseline neutrino experiment

    International Nuclear Information System (INIS)

    The OPERA neutrino detector built in the underground Gran Sasso Laboratory is designed to detect νμ → ντ oscillations in direct appearance mode. The hybrid apparatus consists of an emulsion/lead target complemented by electronic detectors. It is placed in the long-baseline CERN to Gran Sasso neutrino beam (CNGS) 730 km away from the source. The experimental setup and ancillary facilities used to extract data recorded in the emulsion will be described, with the special procedures used to locate the interactions vertices and detect short decay topologies. OPERA is taking data since 2008. A first ντ interaction candidate was already published in 2010. An improved analysis scheme associated with a more detailed simulation has been developed and new results with increased statistics will be presented.

  8. Adapting a Cryogenic Sapphire Oscillator for Very Long Baseline Interferometry

    CERN Document Server

    Doeleman, Sheperd; Rogers, Alan; Hartnett, John; Tobar, Michael; Nand, Nitin; 10.1086/660156

    2011-01-01

    Extension of very long baseline interferometry (VLBI) to observing wavelengths shorter than 1.3mm provides exceptional angular resolution (~20 micro arcsec) and access to new spectral regimes for the study of astrophysical phenomena. To maintain phase coherence across a global VLBI array at these wavelengths requires that ultrastable frequency references be used for the heterodyne receivers at all participating telescopes. Hydrogen masers have traditionally been used as VLBI references, but atmospheric turbulence typically limits (sub) millimeter VLBI coherence times to ~1-30 s. Cryogenic Sapphire Oscillators (CSO) have better stability than Hydrogen masers on these time scale and are potential alternatives to masers as VLBI references. Here, We describe the design, implementation and tests of a system to produce a 10 MHz VLBI frequency standard from the microwave (11.2 GHz) output of a CSO. To improve long-term stability of the new reference, the CSO was locked to the timing signal from the Global Positionin...

  9. Integrated Baseline Bystem (IBS) Version 1.03: Models guide

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    The Integrated Baseline System)(IBS), operated by the Federal Emergency Management Agency (FEMA), is a system of computerized tools for emergency planning and analysis. This document is the models guide for the IBS and explains how to use the emergency related computer models. This document provides information for the experienced system user, and is the primary reference for the computer modeling software supplied with the system. It is designed for emergency managers and planners, and others familiar with the concepts of computer modeling. Although the IBS manual set covers basic and advanced operations, it is not a complete reference document set. Emergency situation modeling software in the IBS is supported by additional technical documents. Some of the other IBS software is commercial software for which more complete documentation is available. The IBS manuals reference such documentation where necessary.

  10. PUREX Plant aggregate area management study technical baseline report

    International Nuclear Information System (INIS)

    The PUREX aggregate area is made up of six operable units; 200-PO-1 through 200-PO-6 and consists of liquid and solid waste disposal sites in the vicinity of, and related to, PUREX Plant operations. This report describes PUREX and its waste sites, including cribs, french drains, septic tanks and drain fields, trenches and ditches, ponds, catch tanks, settling tanks, diversion boxes, underground tank farms, and the lines and encasements that connect them. Each waste site in the aggregate area is described separately. Close relationships between waste units, such as overflow from one to another, are also discussed. This document provides a technical baseline of the aggregate area and results from an environmental investigation. This document is based upon review and evaluation of numerous Hanford Site current and historical reports, drawings and photographs, supplemented with site inspections and employee interviews. No intrusive field investigations or sampling were conducted

  11. Impact of selected energy conservation technologies on baseline demands

    Energy Technology Data Exchange (ETDEWEB)

    Doernberg, A

    1977-09-01

    This study is an application of the modeling and demand projection capability existing at Brookhaven National Laboratory to specific options in energy conservation. Baseline energy demands are modified by introducing successively three sets of conservation options. The implementation of improved building standards and the use of co-generation in industry are analyzed in detail and constitute the body of this report. Two further sets of energy demands are presented that complete the view of a low energy use, ''conservation'' scenario. An introduction to the report covers the complexities in evaluating ''conservation'' in view of the ways it is inextricably linked to technology, prices, policy, and the mix of output in the economy. The term as used in this report is narrowly defined, and methodologies are suggested by which these other aspects listed can be studied in the future.

  12. System maintenance verification and validation plan for the TWRS controlled baseline database system

    International Nuclear Information System (INIS)

    TWRS Controlled Baseline Database, formally known as the Performance Measurement Control System, is used to track and monitor TWRS project management baseline information. This document contains the verification and validation approach for system documentation changes within the database system

  13. A Danish survey of spinal cord stimulation baseline data: First results from a national neuromodulation database

    DEFF Research Database (Denmark)

    Meier, Kaare; Scherer, Christian; Rosenlund, Christina; Gulisano, Helga Angela; Enggaard, Thomas Peter; Willumsen, Lisette; Knudsen, Anne Lene Høst; Rasmusson, Mattias; Sørensen, Jens Christian Hedemann

    A Danish survey of spinal cord stimulation baseline data: First results from a national neuromodulation database......A Danish survey of spinal cord stimulation baseline data: First results from a national neuromodulation database...

  14. Baseline (1961-1990) average total precipitation (inches) for Alaska and Western Canada.

    Data.gov (United States)

    Arctic Landscape Conservation Cooperative — Baseline (1961-1990) average total precipitation (inches) for Alaska and Western Canada. Baseline results for 1961-1990 are derived from Climate Research Unit (CRU)...

  15. Baseline (1961-1990) average air temperature (degree C) for Alaska and Western Canada.

    Data.gov (United States)

    Arctic Landscape Conservation Cooperative — Baseline (1961-1990) average air temperature (degree C) for Alaska and Western Canada. Baseline results for 1961-1990 are derived from Climate Research Unit (CRU)...

  16. Fully integrated current-mode CMOS gated baseline restorer circuits

    International Nuclear Information System (INIS)

    Design and performance results for three different fully-integrated gated baseline restorer (BLR) circuits used in a new PET current-mode front-end CMOS ASIC are presented. The BLR for each of the three gated integrator channels is a differential current-in to single ended current-out circuit with a correction bandwidth of 100 kHz set by a 40 pF on-chip capacitor using pole splitting techniques. The BLRs for the constant fraction discriminator (CFD) constant fraction and arming comparators are differential current-in to voltage-out circuits with correction bandwidths of 5 MHz and 1 MHz set by on-chip capacitors of 10 pF and 2.5 pF respectively. The BLR circuits are capable of correcting differential input current offsets of ±40 microA for the gated integrator circuits, ±100 microA for the CFD constant fraction comparator circuit, and ± 160 microA for the CFD arming comparator circuit. Use of the BLR circuits allows photomultiplier tube (PMT) detector inputs to be ac coupled and all slow (gated integrator) and fast (CFD timing) signal processing channels to be dc coupled. The BLR circuits correct for count-rate dependent baseline shifts due to detector ac coupling and correct for accumulated CMOS dc offsets in the signal processing channels. Gated integrator input offset currents are maintained below 50 nA, keeping the gated integrator output error below 10 mV for an 850 ns integration period. CFD constant fraction comparator input offset is maintained at sub millivolt levels, and arming comparator threshold is maintained at a 0--0.48 V level under on-board DAC control

  17. Automated baseline change detection - Phases 1 and 2. Final report

    International Nuclear Information System (INIS)

    The primary objective of this project is to apply robotic and optical sensor technology to the operational inspection of mixed toxic and radioactive waste stored in barrels, using Automated Baseline Change Detection (ABCD), based on image subtraction. Absolute change detection is based on detecting any visible physical changes, regardless of cause, between a current inspection image of a barrel and an archived baseline image of the same barrel. Thus, in addition to rust, the ABCD system can also detect corrosion, leaks, dents, and bulges. The ABCD approach and method rely on precise camera positioning and repositioning relative to the barrel and on feature recognition in images. The ABCD image processing software was installed on a robotic vehicle developed under a related DOE/FETC contract DE-AC21-92MC29112 Intelligent Mobile Sensor System (IMSS) and integrated with the electronics and software. This vehicle was designed especially to navigate in DOE Waste Storage Facilities. Initial system testing was performed at Fernald in June 1996. After some further development and more extensive integration the prototype integrated system was installed and tested at the Radioactive Waste Management Facility (RWMC) at INEEL beginning in April 1997 through the present (November 1997). The integrated system, composed of ABCD imaging software and IMSS mobility base, is called MISS EVE (Mobile Intelligent Sensor System--Environmental Validation Expert). Evaluation of the integrated system in RWMC Building 628, containing approximately 10,000 drums, demonstrated an easy to use system with the ability to properly navigate through the facility, image all the defined drums, and process the results into a report delivered to the operator on a GUI interface and on hard copy. Further work is needed to make the brassboard system more operationally robust

  18. Automated baseline change detection -- Phases 1 and 2. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Byler, E.

    1997-10-31

    The primary objective of this project is to apply robotic and optical sensor technology to the operational inspection of mixed toxic and radioactive waste stored in barrels, using Automated Baseline Change Detection (ABCD), based on image subtraction. Absolute change detection is based on detecting any visible physical changes, regardless of cause, between a current inspection image of a barrel and an archived baseline image of the same barrel. Thus, in addition to rust, the ABCD system can also detect corrosion, leaks, dents, and bulges. The ABCD approach and method rely on precise camera positioning and repositioning relative to the barrel and on feature recognition in images. The ABCD image processing software was installed on a robotic vehicle developed under a related DOE/FETC contract DE-AC21-92MC29112 Intelligent Mobile Sensor System (IMSS) and integrated with the electronics and software. This vehicle was designed especially to navigate in DOE Waste Storage Facilities. Initial system testing was performed at Fernald in June 1996. After some further development and more extensive integration the prototype integrated system was installed and tested at the Radioactive Waste Management Facility (RWMC) at INEEL beginning in April 1997 through the present (November 1997). The integrated system, composed of ABCD imaging software and IMSS mobility base, is called MISS EVE (Mobile Intelligent Sensor System--Environmental Validation Expert). Evaluation of the integrated system in RWMC Building 628, containing approximately 10,000 drums, demonstrated an easy to use system with the ability to properly navigate through the facility, image all the defined drums, and process the results into a report delivered to the operator on a GUI interface and on hard copy. Further work is needed to make the brassboard system more operationally robust.

  19. GLoBES: General Long Baseline Experiment Simulator

    Science.gov (United States)

    Huber, Patrick; Kopp, Joachim; Lindner, Manfred; Rolinec, Mark; Winter, Walter

    2007-09-01

    GLoBES (General Long Baseline Experiment Simulator) is a flexible software package to simulate neutrino oscillation long baseline and reactor experiments. On the one hand, it contains a comprehensive abstract experiment definition language (AEDL), which allows to describe most classes of long baseline experiments at an abstract level. On the other hand, it provides a C-library to process the experiment information in order to obtain oscillation probabilities, rate vectors, and Δχ-values. Currently, GLoBES is available for GNU/Linux. Since the source code is included, the port to other operating systems is in principle possible. GLoBES is an open source code that has previously been described in Computer Physics Communications 167 (2005) 195 and in Ref. [7]). The source code and a comprehensive User Manual for GLoBES v3.0.8 is now available from the CPC Program Library as described in the Program Summary below. The home of GLobES is http://www.mpi-hd.mpg.de/~globes/. Program summaryProgram title: GLoBES version 3.0.8 Catalogue identifier: ADZI_v1_0 Program summary URL:http://cpc.cs.qub.ac.uk/summaries/ADZI_v1_0.html Program obtainable from: CPC Program Library, Queen's University, Belfast, N. Ireland Licensing provisions: Standard CPC licence, http://cpc.cs.qub.ac.uk/licence/licence.html No. of lines in distributed program, including test data, etc.: 145 295 No. of bytes in distributed program, including test data, etc.: 1 811 892 Distribution format: tar.gz Programming language: C Computer: GLoBES builds and installs on 32bit and 64bit Linux systems Operating system: 32bit or 64bit Linux RAM: Typically a few MBs Classification: 11.1, 11.7, 11.10 External routines: GSL—The GNU Scientific Library, www.gnu.org/software/gsl/ Nature of problem: Neutrino oscillations are now established as the leading flavor transition mechanism for neutrinos. In a long history of many experiments, see, e.g., [1], two oscillation frequencies have been identified: The fast atmospheric

  20. COMPARISON OF THREE METHODS TO PROJECT FUTURE BASELINE CARBON EMISSIONS IN TEMPERATE RAINFOREST, CURINANCO, CHILE

    Energy Technology Data Exchange (ETDEWEB)

    Patrick Gonzalez; Antonio Lara; Jorge Gayoso; Eduardo Neira; Patricio Romero; Leonardo Sotomayor

    2005-07-14

    evaluate the three methods to project future baseline carbon emissions. Extrapolation from Landsat change detection uses the observed rate of change to estimate change in the near future. Geomod is a software program that models the geographic distribution of change using a defined rate of change. FRCA is an integrated spatial analysis of forest inventory, biodiversity, and remote sensing that produces estimates of forest biodiversity and forest carbon density, spatial data layers of future probabilities of reforestation and deforestation, and a projection of future baseline forest carbon sequestration and emissions for an ecologically-defined area of analysis. For the period 1999-2012, extrapolation from Landsat change detection estimated a loss of 5000 ha and 520,000 t carbon from closed natural forest; Geomod modeled a loss of 2500 ha and 250 000 t; FRCA projected a loss of 4700 {+-} 100 ha and 480,000 t (maximum 760,000 t, minimum 220,000 t). Concerning labor time, extrapolation for Landsat required 90 actual days or 120 days normalized to Bachelor degree level wages; Geomod required 240 actual days or 310 normalized days; FRCA required 110 actual days or 170 normalized days. Users experienced difficulties with an MS-DOS version of Geomod before turning to the Idrisi version. For organizations with limited time and financing, extrapolation from Landsat change provides a cost-effective method. Organizations with more time and financing could use FRCA, the only method where that calculates the deforestation rate as a dependent variable rather than assuming a deforestation rate as an independent variable. This research indicates that best practices for the projection of baseline carbon emissions include integration of forest inventory and remote sensing tasks from the beginning of the analysis, definition of an analysis area using ecological characteristics, use of standard and widely used geographic information systems (GIS) software applications, and the use of species

  1. Single-baseline RTK GNSS Positioning for Hydrographic Surveying

    Science.gov (United States)

    Metin Alkan, Reha; Murat Ozulu, I.; Ilçi, Veli; Kahveci, Muzaffer

    2015-04-01

    Positioning with GNSS technique can be carried out in two ways, absolute and relative. It has been possible to reach a few meters absolute point positioning accuracies in real time after disabling SA permanently in May 2000. Today, accuracies obtainable from absolute point positioning using code observations are not sufficient for most surveying applications. Thus to meet higher accuracy requirements, differential methods using single or dual frequency geodetic-grade GNSS receivers that measure carrier phase have to be used. However, this method requires time-cost field and office works and if the measurement is not carried out with conventional RTK method, user needs a GNSS data processing software to estimate the coordinates. If RTK is used, at least two or more GNSS receivers are required, one as a reference and the other as a rover. Moreover, the distance between the receivers must not exceed 15-20 km in order to be able to rapidly and reliably resolve the carrier phase ambiguities. On the other hand, based on the innovations and improvements in satellite geodesy and GNSS modernization studies occurred within the last decade, many new positioning methods and new approaches have been developed. One of them is Network-RTK (or commonly known as CORS) and the other is Single-baseline RTK. These methods are widely used for many surveying applications in many countries. The user of the system can obtain his/her position within a few cm level of accuracy in real-time with only a single GNSS receiver that has Network RTK (CORS) capability. When compared with the conventional differential and RTK methods, this technique has several significant advantages as it is easy to use and it produces accurate, cost-effective and rapid solutions. In Turkey, establishment of a multi-base RTK network was completed and opened for civilian use in 2009. This network is called CORS-TR and consists of 146 reference stations having about 80-100 km interstation distances. It is possible

  2. Idaho National Laboratory’s Greenhouse Gas FY08 Baseline

    Energy Technology Data Exchange (ETDEWEB)

    Jennifer D. Morton

    2011-06-01

    A greenhouse gas (GHG) inventory is a systematic attempt to account for the production and release of certain gasses generated by an institution from various emission sources. The gasses of interest are those which have become identified by climate science as related to anthropogenic global climate change. This document presents an inventory of GHGs generated during fiscal year (FY) 2008 by Idaho National Laboratory (INL), a Department of Energy (DOE)-sponsored entity, located in southeastern Idaho. Concern about the environmental impact of GHGs has grown in recent years. This, together with a desire to decrease harmful environmental impacts, would be enough to encourage the calculation of a baseline estimate of total GHGs generated at INL. Additionally, INL has a desire to see how its emissions compare with similar institutions, including other DOE national laboratories. Executive Order 13514 requires that federal agencies and institutions document reductions in GHG emissions in the future, and such documentation will require knowledge of a baseline against which reductions can be measured. INL's FY08 GHG inventory was calculated according to methodologies identified in federal GHG guidance documents using operational control boundaries. It measures emissions generated in three Scopes: (1) INL emissions produced directly by stationary or mobile combustion and by fugitive emissions, (2) the share of emissions generated by entities from which INL purchased electrical power, and (3) indirect or shared emissions generated by outsourced activities that benefit INL (occur outside INL's organizational boundaries but are a consequence of INL's activities). This inventory found that INL generated a total of 113,049 MT of CO2-equivalent emissions during FY08. The following conclusions were made from looking at the results of the individual contributors to INL's baseline GHG inventory: (1) Electricity (including the associated transmission and

  3. Idaho National Laboratory’s Greenhouse Gas FY08 Baseline

    Energy Technology Data Exchange (ETDEWEB)

    Jennifer D. Morton

    2010-09-01

    A greenhouse gas (GHG) inventory is a systematic attempt to account for the production and release of certain gasses generated by an institution from various emission sources. The gasses of interest are those which have become identified by climate science as related to anthropogenic global climate change. This document presents an inventory of GHGs generated during fiscal year (FY) 2008 by Idaho National Laboratory (INL), a Department of Energy (DOE)-sponsored entity, located in southeastern Idaho. Concern about the environmental impact of GHGs has grown in recent years. This, together with a desire to decrease harmful environmental impacts, would be enough to encourage the calculation of a baseline estimate of total GHGs generated at the INL. Additionally, the INL has a desire to see how its emissions compare with similar institutions, including other DOE-sponsored national laboratories. Executive Order 13514 requires that federally-sponsored agencies and institutions document reductions in GHG emissions in the future, and such documentation will require knowledge of a baseline against which reductions can be measured. INL’s FY08 GHG inventory was calculated according to methodologies identified in Federal recommendations and an as-yet-unpublished Technical and Support Document (TSD) using operational control boundary. It measures emissions generated in three Scopes: (1) INL emissions produced directly by stationary or mobile combustion and by fugitive emissions, (2) the share of emissions generated by entities from which INL purchased electrical power, and (3) indirect or shared emissions generated by outsourced activities that benefit INL (occur outside INL’s organizational boundaries but are a consequence of INL’s activities). This inventory found that INL generated a total of 114,256 MT of CO2-equivalent emissions during fiscal year 2008 (FY08). The following conclusions were made from looking at the results of the individual contributors to INL

  4. Sources of variation in baseline gene expression levels from toxicogenomics study control animals across multiple laboratories

    Directory of Open Access Journals (Sweden)

    Lee Janice S

    2008-06-01

    Full Text Available Abstract Background The use of gene expression profiling in both clinical and laboratory settings would be enhanced by better characterization of variance due to individual, environmental, and technical factors. Meta-analysis of microarray data from untreated or vehicle-treated animals within the control arm of toxicogenomics studies could yield useful information on baseline fluctuations in gene expression, although control animal data has not been available on a scale and in a form best served for data-mining. Results A dataset of control animal microarray expression data was assembled by a working group of the Health and Environmental Sciences Institute's Technical Committee on the Application of Genomics in Mechanism Based Risk Assessment in order to provide a public resource for assessments of variability in baseline gene expression. Data from over 500 Affymetrix microarrays from control rat liver and kidney were collected from 16 different institutions. Thirty-five biological and technical factors were obtained for each animal, describing a wide range of study characteristics, and a subset were evaluated in detail for their contribution to total variability using multivariate statistical and graphical techniques. Conclusion The study factors that emerged as key sources of variability included gender, organ section, strain, and fasting state. These and other study factors were identified as key descriptors that should be included in the minimal information about a toxicogenomics study needed for interpretation of results by an independent source. Genes that are the most and least variable, gender-selective, or altered by fasting were also identified and functionally categorized. Better characterization of gene expression variability in control animals will aid in the design of toxicogenomics studies and in the interpretation of their results.

  5. Geogenic distribution and baseline concentrations of Cu and Zn in surficial soil of Guiyang, China

    Institute of Scientific and Technical Information of China (English)

    WANG Ji; WANG Shijie; OUYANG Ziyuan; LI Ruiling

    2006-01-01

    This paper describes the environmentally geochemical characteristics of heavy metal pollu tants such as Cu and Zn in the surficial soil of Guiyang, the capital city of Guizhou Province. The baseline concentrations of heavy metals in soil and the geochemical norms have been established to distinguish natural or artificial influence on the environment. Using the statistically analytical methods, we have established the baseline of Cu in Guiyang ( 18.8 mg/kg) and the soil ( over 68.4 mg/kg) may suffer Cu contamination. The data of Zn are 46.3 mg/kg and 112.0 mg/kg. Geoaccumulation index analysis indicated that the surficial soil that has suffered non-pollution to mid-pollution of Cu accounts for 38%, 38%, and 22% for mid-pollution, and only 2% between mid-pollution to severe pollution. Surficial soil that has suffered non-pollution to mid-pollution of Zn accounts for 41%, 50%, and 7% for mid-pollution, and only 2% between mid-pollution to severe pollution. The maximal degree of Cu contamination is 5.09 in the surficial soil of Guiyang. Surficial soil that has not suffered Cu pollution accounts for 53.2%. The total pollution degree of Cu is slightly over zero. So the surficial soil of Guiyang has suffered slight Cu pollution. The maximum value of Zn contamination degree is 2.85 in the surficial soil of Guiyang. 77.8% of the surficial soil has not yet suffered any Zn pollution. The total pollution degree of Zn is less than zero.So the surficial soil in Guiyang is free from pollution of Zn.

  6. The Reversal Intervention for Metabolic Syndrome (TRIMS study: rationale, design, and baseline data

    Directory of Open Access Journals (Sweden)

    Troughton Jacqui

    2011-05-01

    Full Text Available Abstract Background Recent attention has focused on strategies to combat the forecast epidemic of type-2 diabetes (T2DM and its major vascular sequelae. Metabolic syndrome (MetS comprises a constellation of factors that increase the risk of cardiovascular disease (CVD and T2DM. Our study aims to develop a structured self-management education programme for people with MetS, which includes management of cardiovascular and diabetes risk factors, and to determine its impact. This paper describes the rationale and design of the TRIMS study, including intervention development, and presents baseline data. Methods Subjects recruited from a mixed-ethnic population with MetS were randomised to intervention or control arms. The intervention arm received structured group education based on robust psychological theories and current evidence. The control group received routine care. Follow-up data will be collected at 6 and 12 months. The primary outcome measure will be reversal of metabolic syndrome in the intervention group subjects compared to controls at 12 months follow-up. Results 82 participants (44% male, 22% South Asian were recruited between November 2009 and July 2010. Baseline characteristics were similar for both the intervention (n = 42 and control groups (n = 40. Median age was 63 years (IQR 57 - 67, mean waist size 106 cm (SD ± 11, and prescribing of statins and anti-hypertensives was 51% in each case. Conclusion Results will provide information on changes in diabetes and CVD risk factors and help to inform primary prevention strategies in people with MetS from varied ethnic backgrounds who are at high risk of developing T2DM and CVD. Information gathered in relation to the programme's acceptability and effectiveness in a multi-ethnic population would ensure that our results are widely applicable. Trial registration The study is registered at ClinicalTrials.gov, study identifier: NCT01043770.

  7. Operationalizing clean development mechanism baselines: A case study of China's electrical sector

    Science.gov (United States)

    Steenhof, Paul A.

    The global carbon market is rapidly developing as the first commitment period of the Kyoto Protocol draws closer and Parties to the Protocol with greenhouse gas (GHG) emission reduction targets seek alternative ways to reduce their emissions. The Protocol includes the Clean Development Mechanism (CDM), a tool that encourages project-based investments to be made in developing nations that will lead to an additional reduction in emissions. Due to China's economic size and rate of growth, technological characteristics, and its reliance on coal, it contains a large proportion of the global CDM potential. As China's economy modernizes, more technologies and processes are requiring electricity and demand for this energy source is accelerating rapidly. Relatively inefficient technology to generate electricity in China thereby results in the electrical sector having substantial GHG emission reduction opportunities as related to the CDM. In order to ensure the credibility of the CDM in leading to a reduction in GHG emissions, it is important that the baseline method used in the CDM approval process is scientifically sound and accessible for both others to use and for evaluation purposes. Three different methods for assessing CDM baselines and environmental additionality are investigated in the context of China's electrical sector: a method based on a historical perspective of the electrical sector (factor decomposition), a method structured upon a current perspective (operating and build margins), and a simulation of the future (dispatch analysis). Assessing future emission levels for China's electrical sector is a very challenging task given the complexity of the system, its dynamics, and that it is heavily influenced by internal and external forces, but of the different baseline methods investigated, dispatch modelling is best suited for the Chinese context as it is able to consider the important regional and temporal dimensions of its economy and its future development

  8. Characteristics of Applicants to Postdoctoral Dental Education Programs.

    Science.gov (United States)

    Solomon, Eric S.; And Others

    1991-01-01

    Analysis of characteristics of students (n=1,684) using the Postdoctoral Application Support Service found significant differences in applicants to various program areas. Applicants to pediatric programs had the most varied characteristics; applicants to oral and maxillofacial surgery were the most homogeneous. The study provides baseline data for…

  9. Development Of Regional Climate Mitigation Baseline For A DominantAgro-Ecological Zone Of Karnataka, India

    Energy Technology Data Exchange (ETDEWEB)

    Sudha, P.; Shubhashree, D.; Khan, H.; Hedge, G.T.; Murthy, I.K.; Shreedhara, V.; Ravindranath, N.H.

    2007-06-01

    Setting a baseline for carbon stock changes in forest andland use sector mitigation projects is an essential step for assessingadditionality of the project. There are two approaches for settingbaselines namely, project-specific and regional baseline. This paperpresents the methodology adopted for estimating the land available formitigation, for developing a regional baseline, transaction cost involvedand a comparison of project-specific and regional baseline. The studyshowed that it is possible to estimate the potential land and itssuitability for afforestation and reforestation mitigation projects,using existing maps and data, in the dry zone of Karnataka, southernIndia. The study adopted a three-step approach for developing a regionalbaseline, namely: i) identification of likely baseline options for landuse, ii) estimation of baseline rates of land-use change, and iii)quantification of baseline carbon profile over time. The analysis showedthat carbon stock estimates made for wastelands and fallow lands forproject-specific as well as the regional baseline are comparable. Theratio of wasteland Carbon stocks of a project to regional baseline is1.02, and that of fallow lands in the project to regional baseline is0.97. The cost of conducting field studies for determination of regionalbaseline is about a quarter of the cost of developing a project-specificbaseline on a per hectare basis. The study has shown the reliability,feasibility and cost-effectiveness of adopting regional baseline forforestry sectormitigation projects.

  10. National INFOSEC technical baseline: multi-level secure systems

    Energy Technology Data Exchange (ETDEWEB)

    Anderson, J P

    1998-09-28

    The purpose of this report is to provide a baseline description of the state of multilevel processor/processing to the INFOSEC Research Council and at their discretion to the R&D community at large. From the information in the report, it is hoped that the members of the IRC will be aware of gaps in MLS research. A primary purpose is to bring IRC and the research community members up to date on what is happening in the MLS arena. The review will attempt to cover what MLS products are still available, and to identify companies who still offer MLS products. We have also attempted to identify requirements for MLS by interviewing senior officers of the Intelligence community as well as those elements of DoD and DOE who are or may be interested in procuring MLS products for various applications. The balance of the report consists of the following sections; a background review of the highlights of the developments of MLS, a quick summary of where we are today in terms of products, installations, and companies who are still in the business of supplying MLS systems [or who are developing MLS system], the requirements as expressed by senior members of the Intelligence community and DoD and DOE, issues and unmet R&D challenges surrounding MLS, and finally a set of recommended research topics.

  11. GPS survey in long baseline neutrino-oscillation measurement

    CERN Document Server

    Noumi, H; Inagaki, T; Hasegawa, T; Katoh, Y; Kohama, M; Kurodai, M; Kusano, E; Maruyama, T; Minakawa, M; Nakamura, K; Nishikawa, K; Sakuda, M; Suzuki, Y; Takasaki, M; Tanaka, K H; Yamanoi, Y; 10.1109/TNS.2004.836042

    2004-01-01

    We made a series of surveys to obtain neutrino beam line direction toward SuperKamiokande (SK) at a distance of 250 km for the long- baseline neutrino oscillation experiment at KEK. We found that the beam line is directed to SK within 0.03 mr and 0.09 mr (in sigma) in the horizontal and vertical directions, respectively. During beam operation, we monitored the muon distribution from secondary pions produced at the target and collected by a magnetic horn system. We found that the horn system functions like a lens of a point-to- parallel optics with magnification of approximately -100 and the focal length of 2.3 m. Namely, a small displacement of the primary beam position at the target is magnified about a factor -100 at the muon centroid, while the centroid position is almost stable against a change of the incident angle of the primary beam. Therefore, the muon centroid can be a useful monitor of the neutrino beam direction. We could determine the muon centroid within 6 mm and 12 mm in horizontal and vertical ...

  12. Pentek concrete scabbling system: Baseline report; Greenbook (chapter)

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-07-31

    The Pentek scabbling technology was tested at Florida International University (FIU) and is being evaluated as a baseline technology. This report evaluates it for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The Pentek concrete scabbling system consisted of the MOOSE, SQUIRREL-I, and SQUIRREL-III scabblers. The scabblers are designed to scarify concrete floors and slabs using cross-section, tungsten carbide tipped bits. The bits are designed to remove concrete in 318 inch increments. The bits are either 9-tooth or demolition type. The scabblers are used with a vacuum system designed to collect and filter the concrete dust and contamination that is removed from the surface. The safety and health evaluation conducted during the testing demonstration focused on two main areas of exposure: dust and noise. Dust exposure was minimal, but noise exposure was significant. Further testing for each of these exposures is recommended. Because of the outdoor environment where the testing demonstration took place, results may be inaccurate. It is feasible that the dust and noise levels will be higher in an enclosed operating environment. Other areas of concern were arm-hand vibration, whole-body vibration, ergonomics, heat stress, tripping hazards, electrical hazards, machine guarding, and lockout/tagout.

  13. A very simple baseline restorer for nuclear applications

    CERN Document Server

    Arnaboldi, Claudio

    2003-01-01

    We present a series of Baseline Restorer circuits (BLR) all based on a very simple and compact configuration. The circuits are able to withstand signals shaped as fast as 10ns or as slow as hundreds of ms. These BLRs are improved versions of an already existing solution that has shown outstanding performances. We have now introduced new features to the original configuration capable of improving the operation of the stationary condition of the stage that precedes the BLR output. This way the response of the circuit to the incoming signal is further improved. In addition, special attention has been paid to obtain large speed of response. Signal rates as large as 10MHz with large pile-up percentage are easily supported. This property is particularly suitable for the next generation of experiments at the large hadron colliders at CERN. One version of the described BLRs is presently used in the analog section of the trigger system of the experiment CUORICINO, an array consisting of 70 large mass bolometric detect...

  14. Neutrino oscillations on the way to long-baseline experiments

    CERN Document Server

    Ryabov, V A

    2003-01-01

    The motivations and physical objectives of experiments in the search for nu /sub mu / to nu /sub e/, nu /sub tau / oscillations in long- baseline accelerator neutrino beams are reviewed. Neutrino beams, detectors, and methods for detecting oscillations (detection of the disappearance of nu /sub mu /, and the appearance of nu /sub e/ and nu /sub tau /) in the current K2K (KEK to Super Kamiokande) experiment and in the MINOS (FNAL to Soudan) and OPERA (CERN to Gran Sasso) near-future experiments are discussed. Possibilities of measuring the oscillation parameters in these experiments are considered in connection with new data obtained in CHOOZ and Palo Verde reactor experiments, the solar neutrino deficit and nu /sub mu // nu /sub e/ anomaly of atmospheric neutrinos, which are observed in large-scale underground detectors, and the excess of nu /sub e/ events in the LSND experiment. Neutrino-oscillation scenarios used in models with three and four (including sterile) types of neutrino, as well as the possibility...

  15. Baseline air quality evaluation for the Venezuelan Orinoco Bitumen Belt

    International Nuclear Information System (INIS)

    To achieve a harmonic relationship between oil exploration and production activities and the environment, Petroleos de Venezuela and its affiliated companies conducted environmental evaluations of the physical and bionic media in the Orinoco Bitumen Belt. This region covers an area of approximately 42000 km2 with estimated bitumen reserves on the order of 3 x 1012 barrels, one of the largest bitumen reservoirs in the world. This paper presents the results of a study of baseline air quality conditions: an emissions inventory, surface and upper layer meteorological conditions and measurements of air quality parameters of interest (CO, HC, NOx, SO2, H2S and T.S.P.) taken by a network of automated air quality stations using standard international reference techniques. The temporal (hourly and daily basis) and spatial air quality variability and the variables/activities that might determine the observed trends are discussed. NO, NO2, SO2 and H2S concentrations were lower than the detection limits of the analytical methods, while O3 and CO 1-hour average levels ranged from 5-30 ppb and 0.5-1.8 ppm, respectively, and T.S.P. daily means varied from 10-50 μg/m3, all of which is close to natural background concentrations. Maximum hourly average reactive hydrocarbon concentrations of 0.37 ppm were found near a producing oil field

  16. Scientific Opportunities with the Long-Baseline Neutrino Experiment

    Energy Technology Data Exchange (ETDEWEB)

    Adams, C.; et al.

    2013-07-28

    In this document, we describe the wealth of science opportunities and capabilities of LBNE, the Long-Baseline Neutrino Experiment. LBNE has been developed to provide a unique and compelling program for the exploration of key questions at the forefront of particle physics. Chief among the discovery opportunities are observation of CP symmetry violation in neutrino mixing, resolution of the neutrino mass hierarchy, determination of maximal or near-maximal mixing in neutrinos, searches for nucleon decay signatures, and detailed studies of neutrino bursts from galactic supernovae. To fulfill these and other goals as a world-class facility, LBNE is conceived around four central components: (1) a new, intense wide-band neutrino source at Fermilab, (2) a fine-grained `near' neutrino detector just downstream of the source, (3) the Sanford Underground Research Facility (SURF) in Lead, South Dakota at an optimal distance (~1300 km) from the neutrino source, and (4) a massive liquid argon time-projection chamber (LArTPC) deployed there as a 'far' detector. The facilities envisioned are expected to enable many other science opportunities due to the high event rates and excellent detector resolution from beam neutrinos in the near detector and atmospheric neutrinos in the far detector. This is a mature, well developed, world class experiment whose relevance, importance, and probability of unearthing critical and exciting physics has increased with time.

  17. Trunk muscle activation during golf swing: Baseline and threshold.

    Science.gov (United States)

    Silva, Luís; Marta, Sérgio; Vaz, João; Fernandes, Orlando; Castro, Maria António; Pezarat-Correia, Pedro

    2013-10-01

    There is a lack of studies regarding EMG temporal analysis during dynamic and complex motor tasks, such as golf swing. The aim of this study is to analyze the EMG onset during the golf swing, by comparing two different threshold methods. Method A threshold was determined using the baseline activity recorded between two maximum voluntary contraction (MVC). Method B threshold was calculated using the mean EMG activity for 1000ms before the 500ms prior to the start of the Backswing. Two different clubs were also studied. Three-way repeated measures ANOVA was used to compare methods, muscles and clubs. Two-way mixed Intraclass Correlation Coefficient (ICC) with absolute agreement was used to determine the methods reliability. Club type usage showed no influence in onset detection. Rectus abdominis (RA) showed the higher agreement between methods. Erector spinae (ES), on the other hand, showed a very low agreement, that might be related to postural activity before the swing. External oblique (EO) is the first being activated, at 1295ms prior impact. There is a similar activation time between right and left muscles sides, although the right EO showed better agreement between methods than left side. Therefore, the algorithms usage is task- and muscle-dependent. PMID:23816264

  18. Future long-baseline neutrino oscillations: View from North America

    International Nuclear Information System (INIS)

    In late 2012 the US Department of Energy gave approval for the first phase of the Long-Baseline Neutrino Experiment (LBNE) that will conduct a broad scientific program including neutrino oscillations, neutrino scattering physics, search for baryon violation, supernova burst neutrinos and other related astrophysical phenomena. The project is now being reformulated as an international facility hosted by the United States. The facility will consist of an intense neutrino beam produced at Fermi National Accelerator Laboratory (Fermilab), a highly capable set of neutrino detectors on the Fermilab campus, and a large underground liquid argon time projection chamber at Sanford Underground Research Facility (SURF) in South Dakota 1300 km from Fermilab. With an intense beam and massive far detector, the experimental program at the facility will make detailed studies of neutrino oscillations, including measurements of the neutrino mass hierarchy and Charge-Parity symmetry violation, by measuring neutrino and anti-neutrino mixing separately. At the near site, the high-statistics neutrino scattering data will allow for many cross section measurements and precision tests of the Standard Model. This presentation will describe the configuration developed by the LBNE collaboration, the broad physics program, and the status of the formation of the international facility

  19. A Survey of Astronomical Research: An Astronomy for Development Baseline

    CERN Document Server

    Ribeiro, V A R M; Cardenas-Avendano, A

    2013-01-01

    Measuring scientific development is a difficult task. Different metrics have been put forward to evaluate scientific development; in this paper we explore a metric that uses the number of peer-reviewed research research articles as an indicator of development in the field of astronomy. We analyzed the available publication record, using the SAO/NASA Astrophysics Database System, by country affiliation in the time span between 1950 and 2011 for countries with a Gross National Income of less than 14,365 USD in 2010. This represents 149 countries. We propose that this metric identifies countries in `astronomy development' with a culture of research publishing. We also propose that for a country to develop astronomy it should invest in outside expert visits, send their staff abroad to study and establish a culture of scientific publishing. Furthermore, we propose that this paper may be used as a baseline to measure the success of major international projects, such as the International Year of Astronomy 2009.

  20. Future Long-Baseline Neutrino Oscillations: View from North America

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, R. J.

    2015-06-01

    In late 2012 the US Department of Energy gave approval for the first phase of the Long-Baseline Neutrino Experiment (LBNE), that will conduct a broad scientific program including neutrino oscillations, neutrino scattering physics, search for baryon violation, supernova burst neutrinos and other related astrophysical phenomena. The project is now being reformulated as an international facility hosted by the United States. The facility will consist of an intense neutrino beam produced at Fermi National Accelerator Laboratory (Fermilab), a highly capable set of neutrino detectors on the Fermilab campus, and a large underground liquid argon time projection chamber at Sanford Underground Research Facility (SURF) in South Dakota 1300 km from Fermilab. With an intense beam and massive far detector, the experimental program at the facility will make detailed studies of neutrino oscillations, including measurements of the neutrino mass hierarchy and Charge-Parity symmetry violation, by measuring neutrino and anti-neutrino mixing separately. At the near site, the high-statistics neutrino scattering data will allow for many cross section measurements and precision tests of the Standard Model. This presentation will describe the configuration developed by the LBNE collaboration, the broad physics program, and the status of the formation of the international facility.

  1. Future Long-Baseline Neutrino Facilities and Detectors

    Directory of Open Access Journals (Sweden)

    Milind Diwan

    2013-01-01

    Full Text Available We review the ongoing effort in the US, Japan, and Europe of the scientific community to study the location and the detector performance of the next-generation long-baseline neutrino facility. For many decades, research on the properties of neutrinos and the use of neutrinos to study the fundamental building blocks of matter has unveiled new, unexpected laws of nature. Results of neutrino experiments have triggered a tremendous amount of development in theory: theories beyond the standard model or at least extensions of it and development of the standard solar model and modeling of supernova explosions as well as the development of theories to explain the matter-antimatter asymmetry in the universe. Neutrino physics is one of the most dynamic and exciting fields of research in fundamental particle physics and astrophysics. The next-generation neutrino detector will address two aspects: fundamental properties of the neutrino like mass hierarchy, mixing angles, and the CP phase, and low-energy neutrino astronomy with solar, atmospheric, and supernova neutrinos. Such a new detector naturally allows for major improvements in the search for nucleon decay. A next-generation neutrino observatory needs a huge, megaton scale detector which in turn has to be installed in a new, international underground laboratory, capable of hosting such a huge detector.

  2. PCANet: A Simple Deep Learning Baseline for Image Classification?

    Science.gov (United States)

    Chan, Tsung-Han; Jia, Kui; Gao, Shenghua; Lu, Jiwen; Zeng, Zinan; Ma, Yi

    2015-12-01

    In this work, we propose a very simple deep learning network for image classification which comprises only the very basic data processing components: cascaded principal component analysis (PCA), binary hashing, and block-wise histograms. In the proposed architecture, PCA is employed to learn multistage filter banks. It is followed by simple binary hashing and block histograms for indexing and pooling. This architecture is thus named as a PCA network (PCANet) and can be designed and learned extremely easily and efficiently. For comparison and better understanding, we also introduce and study two simple variations to the PCANet, namely the RandNet and LDANet. They share the same topology of PCANet but their cascaded filters are either selected randomly or learned from LDA. We have tested these basic networks extensively on many benchmark visual datasets for different tasks, such as LFW for face verification, MultiPIE, Extended Yale B, AR, FERET datasets for face recognition, as well as MNIST for hand-written digits recognition. Surprisingly, for all tasks, such a seemingly naive PCANet model is on par with the state of the art features, either prefixed, highly hand-crafted or carefully learned (by DNNs). Even more surprisingly, it sets new records for many classification tasks in Extended Yale B, AR, FERET datasets, and MNIST variations. Additional experiments on other public datasets also demonstrate the potential of the PCANet serving as a simple but highly competitive baseline for texture classification and object recognition.

  3. Baseline Gas Turbine Development Program twelfth quarterly progress report

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, F W; Wagner, C E

    1975-10-31

    Progress is reported for a program to demonstrate by 1976 an experimental gas turbine powered automobile which meets the 1978 Federal Emissions Standards, has significantly improved fuel economy, and is competitive in performance, reliability, and potential manufacturing cost with the conventional piston engine powered, standard size American automobile. The endurance engine was modified to incorporate a power turbine drive to the regenerators in order to simulate free rotor (upgraded) conditions. A portable baseline engine fixture complete with controls, intake, exhaust, and transmission is being assembled for odor evaluation. An additional 502 engine hours were accumulated on ceramic regenerators and seals. No core or seal failures were experienced during engine test. Initial fixture tests of zirconia seals show torque levels comparable with nickle oxide seals against the same matrix. An ambient compensation schedule was devised for the upgraded engine integrated control, and the integrated control system specifications were updated. A proposed hydromechanical automotive continuously variable ratio transmission (CVT) was evaluated and approved for preliminary development. Tests of heat rejection to the oil for lined versus linerless insulated engine assemblies indicated no heat loss penalty in omitting the metal liners. A study was made of various power turbine rotor assemblies and a final design was selected. Optimization studies of the two-stage power turbine reduction gears and regenerator spur and worm gears were completed. Initial tests on the fixture for simulating the scaled S-26 upgraded burner have begun.

  4. A SURVEY OF ASTRONOMICAL RESEARCH: A BASELINE FOR ASTRONOMICAL DEVELOPMENT

    International Nuclear Information System (INIS)

    Measuring scientific development is a difficult task. Different metrics have been put forward to evaluate scientific development; in this paper we explore a metric that uses the number of peer-reviewed, and when available non-peer-reviewed, research articles as an indicator of development in the field of astronomy. We analyzed the available publication record, using the Smithsonian Astrophysical Observatory/NASA Astrophysics Database System, by country affiliation in the time span between 1950 and 2011 for countries with a gross national income of less than 14,365 USD in 2010. This represents 149 countries. We propose that this metric identifies countries in ''astronomical development'' with a culture of research publishing. We also propose that for a country to develop in astronomy, it should invest in outside expert visits, send its staff abroad to study, and establish a culture of scientific publishing. Furthermore, we propose that this paper may be used as a baseline to measure the success of major international projects, such as the International Year of Astronomy 2009

  5. Short baseline neutrino oscillations: when entanglement suppresses coherence

    CERN Document Server

    Boyanovsky, Daniel

    2011-01-01

    For neutrino oscillations to take place the entangled quantum state of a neutrino and a charged lepton produced via charged current interactions must be disentangled. Implementing a non-perturbative Wigner-Weisskopf method we obtain the correct \\emph{entangled} quantum state of neutrinos and charged leptons from the (two-body) decay of a parent particle. The source lifetime and disentanglement length scale lead to a suppression of the oscillation probabilities in short-baseline experiments. The suppression is determined by $\\pi\\, L_d/L_{osc}$ where $L_d$ is the \\emph{smallest} of the decay length of the parent particle or the disentanglement length scale. For $L_d \\geq L_{osc}$ coherence and oscillations are suppressed. These effects are more prominent in \\emph{short base line experiments} and at low neutrino energy. We obtain the corrections to the appearance and disappearance probabilities modified by both the lifetime of the source and the disentanglement scale and discuss their implications for accelerato...

  6. Neutrino Oscillation Parameter Sensitivity in Future Long-Baseline Experiments

    Energy Technology Data Exchange (ETDEWEB)

    Bass, Matthew [Colorado State Univ., Fort Collins, CO (United States)

    2014-01-01

    The study of neutrino interactions and propagation has produced evidence for physics beyond the standard model and promises to continue to shed light on rare phenomena. Since the discovery of neutrino oscillations in the late 1990s there have been rapid advances in establishing the three flavor paradigm of neutrino oscillations. The 2012 discovery of a large value for the last unmeasured missing angle has opened the way for future experiments to search for charge-parity symmetry violation in the lepton sector. This thesis presents an analysis of the future sensitivity to neutrino oscillations in the three flavor paradigm for the T2K, NO A, LBNE, and T2HK experiments. The theory of the three flavor paradigm is explained and the methods to use these theoretical predictions to design long baseline neutrino experiments are described. The sensitivity to the oscillation parameters for each experiment is presented with a particular focus on the search for CP violation and the measurement of the neutrino mass hierarchy. The variations of these sensitivities with statistical considerations and experimental design optimizations taken into account are explored. The effects of systematic uncertainties in the neutrino flux, interaction, and detection predictions are also considered by incorporating more advanced simulations inputs from the LBNE experiment.

  7. Baseline Testing of The EV Global E-Bike

    Science.gov (United States)

    Eichenberg, Dennis J.; Kolacz, John S.; Tavernelli, Paul F.

    2001-01-01

    The NASA John H. Glenn Research Center initiated baseline testing of the EV Global E-Bike as a way to reduce pollution in urban areas, reduce fossil fuel consumption and reduce Operating costs for transportation systems. The work was done Linder the Hybrid Power Management (HPM) Program, which includes the Hybrid Electric Transit Bus (HETB). The E-Bike is a state of the art, ground up, hybrid electric bicycle. Unique features of the vehicle's power system include the use of an efficient, 400 W. electric hub motor and a 7-speed derailleur system that permits operation as fully electric, fully pedal, or a combination of the two. Other innovative features, such as regenerative braking through ultracapacitor energy storage are planned. Regenerative braking recovers much of the kinetic energy of the vehicle during deceleration. The E-Bike is an inexpensive approach to advance the state of the art in hybrid technology in a practical application. The project transfers space technology to terrestrial use via nontraditional partners, and provides power system data valuable for future space applications. A description of the E-bike, the results of performance testing, and future vehicle development plans is the subject of this report. The report concludes that the E-Bike provides excellent performance, and that the implementation of ultracapacitors in the power system can provide significant performance improvements.

  8. Baseline Testing of the EV Global E-Bike SX

    Science.gov (United States)

    Eichenherg, Dennis J.; Kolacz, John S.; Tavernelli, Paul F.

    2001-01-01

    The NASA John H. Glenn Research Center initiated baseline testing of the EV Global E-Bike SX as an update of the state of the art in hybrid electric bicycles. The E-bike is seen as a way to reduce pollution in urban areas, reduce fossil fuel consumption, and reduce operating costs for transportation systems. The work was done under the Hybrid Power Management (HPM) Program, which includes the Hybrid Electric Transit Bus (HETB). The SX is a high performance, state of the art, ground up, hybrid electric bicycle. Unique features of the SX's 36 V power system include the use of an efficient, 400 W, electric hub motor, and a seven-speed derailleur system that permits operation as fully electric, fully pedal, or a combination of the two. Other innovative features, such as regenerative braking through ultracapacitor energy storage, are planned. Regenerative braking recovers much of the kinetic energy of the vehicle during deceleration. The E-Bike is an inexpensive approach to advance the state of the art in hybrid technology in a practical application. The project transfers space technology to terrestrial use via nontraditional partners, and provides power system data valuable for future space applications. A description of the SX, the results of performance testing, and future vehicle development plans are given in this report. The report concludes that the SX provides excellent performance, and that the implementation of ultracapacitors in the power system can provide significant performance improvements.

  9. Baseline concentrations of nuclear fuel waste nuclides in the environment

    International Nuclear Information System (INIS)

    Protection of the environment is a key issue in the disposal of long-lived radioactive wastes. To assess the implications of undergound disposal, transport models are commonly used to predict radionuclide concentrations in soil and water. However, an appropriate framework needs to be established to ensure that the predicted concentrations do not impose unacceptable environmental impacts. Here, we suggest baseline environmental concentrations of the most important radionuclides in nuclear fuel waste. We summarize background concentrations of the nuclides in soil and surface water, and suggest Environmental Increments (EI) that could be added to soil and water without causing detectable effects. The EI values are based mostly on natural variability, but some alternative methods are used for radionuclides that are very rare in nature. The background concentrations and EI values are most useful as a screening tool to help identify potentially unacceptable concentrations arising from a disposal concept. When available, we also report data on concentrations that have been measured in the environment without causing an observable effect. This review focuses especially on concentrations applicable to the Canadian Precambrian Shield, as part of the Canadian concept of nuclear fuel waste disposal in a deep, stable geological formation

  10. Accelerator-based Short-baseline Neutrino Oscillation Experiments

    CERN Document Server

    Gollapinni, Sowjanya

    2015-01-01

    Over the last two decades, several experiments have reported anomalous results that could be hinting at the exciting possibility of sterile neutrino states in the $eV^{2}$ mass scale. Liquid Argon Time Projection Chambers (LArTPCs) are a particularly promising technology to explore this physics due to their fine-grained tracking and exceptional calorimetric capabilities. The MicroBooNE experiment, a 170 ton LArTPC scheduled to start taking data very soon with Fermilab's Booster Neutrino Beam (BNB), will combine LArTPC development with the main physics goal of understanding the low-energy electromagnetic anomaly seen by the MiniBooNE experiment. Looking towards the future, MicroBooNE will become a part of the \\textit{short-baseline neutrino} program which expands the physics capabilities of the BNB in many important ways by adding additional LArTPC detectors to search for light sterile neutrinos and bring a definitive resolution to the set of existing experimental anomalies. This paper will give an overview of...

  11. A coherent fiber link for very long baseline interferometry.

    Science.gov (United States)

    Clivati, Cecilia; Costanzo, Giovanni A; Frittelli, Matteo; Levi, Filippo; Mura, Alberto; Zucco, Massimo; Ambrosini, Roberto; Bortolotti, Claudio; Perini, Federico; Roma, Mauro; Calonico, Davide

    2015-11-01

    We realize a coherent fiber link for application in very long baseline interferometry (VLBI) for radio astronomy and geodesy. A 550-km optical fiber connects the Italian National Metrological Institute (INRIM) to a radio telescope in Italy and is used for the primary Cs fountain clock stability and accuracy dissemination. We use an ultrastable laser frequency- referenced to the primary standard as a transfer oscillator; at the radio telescope, an RF signal is generated from the laser by using an optical frequency comb. This scheme now provides the traceability of the local maser to the SI second, realized by the Cs fountain at the 1.7 × 10(-16) accuracy. The fiber link never limits the experiment and is robust enough to sustain radio astronomical campaigns. This experiment opens the possibility of replacing the local hydrogen masers at the VLBI sites with optically-synthesized RF signals. This could improve VLBI resolution by providing more accurate and stable frequency references and, in perspective, by enabling common- clock VLBI based on a network of telescopes connected by fiber links. PMID:26559621

  12. Design studies for a long base-line neutrino beam

    Energy Technology Data Exchange (ETDEWEB)

    Ball, A.E. [European Lab. for Particle Physics (CERN), Geneva (Switzerland); Katsanevas, S. [University of Athens, 104 Solonos, GR-106 80 Athens (Greece); Vassilopoulos, N. [University of Athens, 104 Solonos, GR-106 80 Athens (Greece)

    1996-12-11

    Strong interest has recently been shown in very long base-line neutrino beams, directed at existing or planned massive detector facilities, in order to extend the search for neutrino oscillations. Among such possibilities are beams from CERN pointing towards the Gran Sasso Underground Laboratory in Italy and the NESTOR Underwater Laboratory in the Ionian Sea off the west coast of the Peloponnese. In order to establish the basic parameters, a number of possible configurations for such beams have been studied covering a range of neutrino energy bands; estimates of the neutrino fluxes, event rates and backgrounds at typical detectors are reported. Considerations have been given to the optimum length and radius of the decay tunnels. It is shown that with one year of operation, a neutrino oscillation search down to limits of sin{sup 2} 2{theta}=1.1 x 10{sup -2} and {Delta}m{sup 2}=3.5 x 10{sup -4} eV{sup 2} could be made with currently proposed detectors. (orig.).

  13. Design studies for a long base-line neutrino beam

    International Nuclear Information System (INIS)

    Strong interest has recently been shown in very long base-line neutrino beams, directed at existing or planned massive detector facilities, in order to extend the search for neutrino oscillations. Among such possibilities are beams from CERN pointing towards the Gran Sasso Underground Laboratory in Italy and the NESTOR Underwater Laboratory in the Ionian Sea off the west coast of the Peloponnese. In order to establish the basic parameters, a number of possible configurations for such beams have been studied covering a range of neutrino energy bands; estimates of the neutrino fluxes, event rates and backgrounds at typical detectors are reported. Considerations have been given to the optimum length and radius of the decay tunnels. It is shown that with one year of operation, a neutrino oscillation search down to limits of sin2 2θ=1.1 x 10-2 and Δm2=3.5 x 10-4 eV2 could be made with currently proposed detectors. (orig.)

  14. Updated baseline for a staged Compact Linear Collider

    CERN Document Server

    Boland, M J; Giansiracusa, P J; Lucas, T G; Rassool, R P; Balazs, C; Charles, T K; Afanaciev, K; Emeliantchik, I; Ignatenko, A; Makarenko, V; Shumeiko, N; Patapenka, A; Zhuk, I; Abusleme Hoffman, A C; Diaz Gutierrez, M A; Gonzalez, M Vogel; Chi, Y; He, X; Pei, G; Pei, S; Shu, G; Wang, X; Zhang, J; Zhao, F; Zhou, Z; Chen, H; Gao, Y; Huang, W; Kuang, Y P; Li, B; Li, Y; Shao, J; Shi, J; Tang, C; Wu, X; Ma, L; Han, Y; Fang, W; Gu, Q; Huang, D; Huang, X; Tan, J; Wang, Z; Zhao, Z; Laštovička, T; Uggerhoj, U; Wistisen, T N; Aabloo, A; Eimre, K; Kuppart, K; Vigonski, S; Zadin, V; Aicheler, M; Baibuz, E; Brücken, E; Djurabekova, F; Eerola, P; Garcia, F; Haeggström, E; Huitu, K; Jansson, V; Karimaki, V; Kassamakov, I; Kyritsakis, A; Lehti, S; Meriläinen, A; Montonen, R; Niinikoski, T; Nordlund, K; Österberg, K; Parekh, M; Törnqvist, N A; Väinölä, J; Veske, M; Farabolini, W; Mollard, A; Napoly, O; Peauger, F; Plouin, J; Bambade, P; Chaikovska, I; Chehab, R; Davier, M; Kaabi, W; Kou, E; LeDiberder, F; Pöschl, R; Zerwas, D; Aimard, B; Balik, G; Baud, J-P; Blaising, J-J; Brunetti, L; Chefdeville, M; Drancourt, C; Geoffroy, N; Jacquemier, J; Jeremie, A; Karyotakis, Y; Nappa, J M; Vilalte, S; Vouters, G; Bernard, A; Peric, I; Gabriel, M; Simon, F; Szalay, M; van der Kolk, N; Alexopoulos, T; Gazis, E N; Gazis, N; Ikarios, E; Kostopoulos, V; Kourkoulis, S; Gupta, P D; Shrivastava, P; Arfaei, H; Dayyani, M K; Ghasem, H; Hajari, S S; Shaker, H; Ashkenazy, Y; Abramowicz, H; Benhammou, Y; Borysov, O; Kananov, S; Levy, A; Levy, I; Rosenblat, O; D'Auria, G; Di Mitri, S; Abe, T; Aryshev, A; Higo, T; Makida, Y; Matsumoto, S; Shidara, T; Takatomi, T; Takubo, Y; Tauchi, T; Toge, N; Ueno, K; Urakawa, J; Yamamoto, A; Yamanaka, M; Raboanary, R; Hart, R; van der Graaf, H; Eigen, G; Zalieckas, J; Adli, E; Lillestøl, R; Malina, L; Pfingstner, J; Sjobak, K N; Ahmed, W; Asghar, M I; Hoorani, H; Bugiel, S; Dasgupta, R; Firlej, M; Fiutowski, T A; Idzik, M; Kopec, M; Kuczynska, M; Moron, J; Swientek, K P; Daniluk, W; Krupa, B; Kucharczyk, M; Lesiak, T; Moszczynski, A; Pawlik, B; Sopicki, P; Wojtoń, T; Zawiejski, L; Kalinowski, J; Krawczyk, M; Żarnecki, A F; Firu, E; Ghenescu, V; Neagu, A T; Preda, T; Zgura, I-S; Aloev, A; Azaryan, N; Budagov, J; Chizhov, M; Filippova, M; Glagolev, V; Gongadze, A; Grigoryan, S; Gudkov, D; Karjavine, V; Lyablin, M; Olyunin, A; Samochkine, A; Sapronov, A; Shirkov, G; Soldatov, V; Solodko, A; Solodko, E; Trubnikov, G; Tyapkin, I; Uzhinsky, V; Vorozhtov, A; Levichev, E; Mezentsev, N; Piminov, P; Shatilov, D; Vobly, P; Zolotarev, K; Bozovic-Jelisavcic, I; Kacarevic, G; Lukic, S; Milutinovic-Dumbelovic, G; Pandurovic, M; Iriso, U; Perez, F; Pont, M; Trenado, J; Aguilar-Benitez, M; Calero, J; Garcia-Tabares, L; Gavela, D; Gutierrez, J L; Lopez, D; Toral, F; Moya, D; Ruiz-Jimeno, A; Vila, I; Argyropoulos, T; Gutierrez, C Blanch; Boronat, M; Esperante, D; Faus-Golfe, A; Fuster, J; Fuster Martinez, N; Galindo Muñoz, N; García, I; Giner Navarro, J; Ros, E; Vos, M; Brenner, R; Ekelöf, T; Jacewicz, M; Ögren, J; Olvegård, M; Ruber, R; Ziemann, V; Aguglia, D; Alipour Tehrani, N; Aloev, A; Andersson, A; Andrianala, F; Antoniou, F; Artoos, K; Atieh, S; Ballabriga Sune, R; Barnes, M J; Barranco Garcia, J; Bartosik, H; Belver-Aguilar, C; Benot Morell, A; Bett, D R; Bettoni, S; Blanchot, G; Blanco Garcia, O; Bonnin, X A; Brunner, O; Burkhardt, H; Calatroni, S; Campbell, M; Catalan Lasheras, N; Cerqueira Bastos, M; Cherif, A; Chevallay, E; Constance, B; Corsini, R; Cure, B; Curt, S; Dalena, B; Dannheim, D; De Michele, G; De Oliveira, L; Deelen, N; Delahaye, J P; Dobers, T; Doebert, S; Draper, M; Duarte Ramos, F; Dubrovskiy, A; Elsener, K; Esberg, J; Esposito, M; Fedosseev, V; Ferracin, P; Fiergolski, A; Foraz, K; Fowler, A; Friebel, F; Fuchs, J-F; Fuentes Rojas, C A; Gaddi, A; Garcia Fajardo, L; Garcia Morales, H; Garion, C; Gatignon, L; Gayde, J-C; Gerwig, H; Goldblatt, A N; Grefe, C; Grudiev, A; Guillot-Vignot, F G; Gutt-Mostowy, M L; Hauschild, M; Hessler, C; Holma, J K; Holzer, E; Hourican, M; Hynds, D; Inntjore Levinsen, Y; Jeanneret, B; Jensen, E; Jonker, M; Kastriotou, M; Kemppinen, J M K; Kieffer, R B; Klempt, W; Kononenko, O; Korsback, A; Koukovini Platia, E; Kovermann, J W; Kozsar, C-I; Kremastiotis, I; Kulis, S; Latina, A; Leaux, F; Lebrun, P; Lefevre, T; Linssen, L; Llopart Cudie, X; Maier, A A; Mainaud Durand, H; Manosperti, E; Marelli, C; Marin Lacoma, E; Martin, R; Mazzoni, S; Mcmonagle, G; Mete, O; Mether, L M; Modena, M; Münker, R M; Muranaka, T; Nebot Del Busto, E; Nikiforou, N; Nisbet, D; Nonglaton, J-M; Nuiry, F X; Nürnberg, A; Olvegard, M; Osborne, J; Papadopoulou, S; Papaphilippou, Y; Passarelli, A; Patecki, M; Pazdera, L; Pellegrini, D; Pepitone, K; Perez, F; Perez Codina, E; Perez Fontenla, A; Persson, T H B; Petrič, M; Pitters, F

    2016-01-01

    The Compact Linear Collider (CLIC) is a multi-TeV high-luminosity linear e+e- collider under development. For an optimal exploitation of its physics potential, CLIC is foreseen to be built and operated in a staged approach with three centre-of-mass energy stages ranging from a few hundred GeV up to 3 TeV. The first stage will focus on precision Standard Model physics, in particular Higgs and top-quark measurements. Subsequent stages will focus on measurements of rare Higgs processes, as well as searches for new physics processes and precision measurements of new states, e.g. states previously discovered at LHC or at CLIC itself. In the 2012 CLIC Conceptual Design Report, a fully optimised 3 TeV collider was presented, while the proposed lower energy stages were not studied to the same level of detail. This report presents an updated baseline staging scenario for CLIC. The scenario is the result of a comprehensive study addressing the performance, cost and power of the CLIC accelerator complex as a function of...

  15. Pentek metal coating removal system: Baseline report; Greenbook (chapter)

    International Nuclear Information System (INIS)

    The Pentek coating removal technology was tested and is being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU's evaluation of efficiency and cost, this report covers evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The Pentek coating removal system consisted of the ROTO-PEEN Scaler, CORNER-CUTTER reg-sign, and VAC-PAC reg-sign. They are designed to remove coatings from steel, concrete, brick, and wood. The Scaler uses 3M Roto Peen tungsten carbide cutters while the CORNER-CUTTER reg-sign uses solid needles for descaling activities. These hand tools are used with the VAC-PAC reg-sign vacuum system to capture dust and debris as removal of the coating takes place. The safety and health evaluation during the testing demonstration focused on two main areas of exposure: dust and noise. Dust exposure minimal, but noise exposure was significant. Further testing for each exposure is recommended because of the environment where the testing demonstration took place. It is feasible that the dust and noise levels will be higher in an enclosed operating environment of different construction. In addition, other areas of concern found were arm-hand vibration, whole-body, ergonomics, heat stress, tripping hazards, electrical hazards, machine guarding, and lockout/tagout

  16. Predicted radiation environment of the Saturn baseline diode

    International Nuclear Information System (INIS)

    Coupled electron/photon Monte Carlo radiation transport was used to predict the radiation environment of the Saturn accelerator for the baseline diode design. The x-ray output has been calculated, as well as energy deposition in CaF2 thermoluminescent dosimetry and silicon. It is found that the design criteria for the radiation environment will be met and that approximately 10 kJ of x rays will be available for simulation experiments, if the diode provides a nominal beam of 2.0-MeV electrons for 20 ns with a peak current of 12.5 MA. The penalty in dose and x-ray output for operating below the nominal energy in order to obtain a softer spectrum is quantified. The penalty for using excessive electron equilibration in the standard packaging of the thermoluminescent dosimeters is shown to be negligible. An intrinsic lack of electron equilibration for silicon elements of components and subsystems is verified for Saturn environments, demonstrating the ambiguity of design criteria based on silicon deposition. Validation of an efficient next-event-estimator method for predicting energy deposition in equilibrated detectors/dosimetry is confirmed. Finally, direct-electron depositions in excess of 1 kJ/g are shown to be easily achievable. 34 refs., 30 figs

  17. B Plant aggregate area management study technical baseline report

    International Nuclear Information System (INIS)

    The B aggregate area is made up of 13 operable units; 200-BP 1 through 200-BP 1 1, 200-IU-6, and 200-SS-1 that consist of liquid and solid waste disposal sites in the vicinity of, and related to, B Plant operations. This report describes B Plant and its waste sites, including cribs, french drains, septic tanks and drain fields, trenches and ditches, ponds, catch tanks, settling tanks, diversion boxes, underground tank farms designed for high-level liquid wastes, and the lines and encasements that connect them. Each waste site in the aggregate area is described separately. Close relationships between waste units, such as overflow from one to another, are also discussed. This document provides a technical baseline of the aggregate area and results from an environmental investigation. This document is based upon review and evaluation of numerous Hanford Site current and historical reports, drawings and photographs, supplemented with site inspections and employee interviews. No intrusive field investigations or sampling were conducted

  18. Pentek concrete scabbling system: Baseline report; Greenbook (chapter)

    International Nuclear Information System (INIS)

    The Pentek scabbling technology was tested at Florida International University (FIU) and is being evaluated as a baseline technology. This report evaluates it for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The Pentek concrete scabbling system consisted of the MOOSE, SQUIRREL-I, and SQUIRREL-III scabblers. The scabblers are designed to scarify concrete floors and slabs using cross-section, tungsten carbide tipped bits. The bits are designed to remove concrete in 318 inch increments. The bits are either 9-tooth or demolition type. The scabblers are used with a vacuum system designed to collect and filter the concrete dust and contamination that is removed from the surface. The safety and health evaluation conducted during the testing demonstration focused on two main areas of exposure: dust and noise. Dust exposure was minimal, but noise exposure was significant. Further testing for each of these exposures is recommended. Because of the outdoor environment where the testing demonstration took place, results may be inaccurate. It is feasible that the dust and noise levels will be higher in an enclosed operating environment. Other areas of concern were arm-hand vibration, whole-body vibration, ergonomics, heat stress, tripping hazards, electrical hazards, machine guarding, and lockout/tagout

  19. Ultra-high pressure water jet: Baseline report

    International Nuclear Information System (INIS)

    The ultra-high pressure waterjet technology was being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU's evaluation of efficiency and cost, this report covers the evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The ultra-high pressure waterjet technology acts as a cutting tool for the removal of surface substrates. The Husky trademark pump feeds water to a lance that directs the high pressure water at the surface to be removed. The safety and health evaluation during the testing demonstration focused on two main areas of exposure. These were dust and noise. The dust exposure was found to be minimal, which would be expected due to the wet environment inherent in the technology, but noise exposure was at a significant level. Further testing for noise is recommended because of the outdoor environment where the testing demonstration took place. In addition, other areas of concern found were arm-hand vibration, ergonomics, heat stress, tripping hazards, electrical hazards, lockout/tagout, fall hazards, slipping hazards, hazards associated with the high pressure water, and hazards associated with air pressure systems

  20. Thermographic Patterns of the Upper and Lower Limbs: Baseline Data

    Science.gov (United States)

    Cassar, Kevin; Camilleri, Kenneth P.; De Raffaele, Clifford; Mizzi, Stephen; Cristina, Stefania

    2015-01-01

    Objectives. To collect normative baseline data and identify any significant differences between hand and foot thermographic distribution patterns in a healthy adult population. Design. A single-centre, randomized, prospective study. Methods. Thermographic data was acquired using a FLIR camera for the data acquisition of both plantar and dorsal aspects of the feet, volar aspects of the hands, and anterior aspects of the lower limbs under controlled climate conditions. Results. There is general symmetry in skin temperature between the same regions in contralateral limbs, in terms of both magnitude and pattern. There was also minimal intersubject temperature variation with a consistent temperature pattern in toes and fingers. The thumb is the warmest digit with the temperature falling gradually between the 2nd and the 5th fingers. The big toe and the 5th toe are the warmest digits with the 2nd to the 4th toes being cooler. Conclusion. Measurement of skin temperature of the limbs using a thermal camera is feasible and reproducible. Temperature patterns in fingers and toes are consistent with similar temperatures in contralateral limbs in healthy subjects. This study provides the basis for further research to assess the clinical usefulness of thermography in the diagnosis of vascular insufficiency. PMID:25648145

  1. Transuranic waste baseline inventory report. Revision No. 3

    International Nuclear Information System (INIS)

    The Transuranic Waste Baseline Inventory Report (TWBIR) establishes a methodology for grouping wastes of similar physical and chemical properties from across the U.S. Department of Energy (DOE) transuranic (TRU) waste system into a series of open-quotes waste profilesclose quotes that can be used as the basis for waste form discussions with regulatory agencies. The purpose of Revisions 0 and 1 of this report was to provide data to be included in the Sandia National Laboratories/New Mexico (SNL/NM) performance assessment (PA) processes for the Waste Isolation Pilot Plant (WIPP). Revision 2 of the document expanded the original purpose and was also intended to support the WIPP Land Withdrawal Act (LWA) requirement for providing the total DOE TRU waste inventory. The document included a chapter and an appendix that discussed the total DOE TRU waste inventory, including nondefense, commercial, polychlorinated biphenyls (PCB)-contaminated, and buried (predominately pre-1970) TRU wastes that are not planned to be disposed of at WIPP

  2. Future long-baseline neutrino oscillations: View from North America

    Energy Technology Data Exchange (ETDEWEB)

    Wilson, Robert J., E-mail: wilson@colostate.edu [Department of Physics, Colorado State University, Fort Collins, CO 80523-1875 (United States)

    2015-07-15

    In late 2012 the US Department of Energy gave approval for the first phase of the Long-Baseline Neutrino Experiment (LBNE) that will conduct a broad scientific program including neutrino oscillations, neutrino scattering physics, search for baryon violation, supernova burst neutrinos and other related astrophysical phenomena. The project is now being reformulated as an international facility hosted by the United States. The facility will consist of an intense neutrino beam produced at Fermi National Accelerator Laboratory (Fermilab), a highly capable set of neutrino detectors on the Fermilab campus, and a large underground liquid argon time projection chamber at Sanford Underground Research Facility (SURF) in South Dakota 1300 km from Fermilab. With an intense beam and massive far detector, the experimental program at the facility will make detailed studies of neutrino oscillations, including measurements of the neutrino mass hierarchy and Charge-Parity symmetry violation, by measuring neutrino and anti-neutrino mixing separately. At the near site, the high-statistics neutrino scattering data will allow for many cross section measurements and precision tests of the Standard Model. This presentation will describe the configuration developed by the LBNE collaboration, the broad physics program, and the status of the formation of the international facility.

  3. Concrete Cleaning, Inc. centrifugal shot blaster: Baseline report; Greenbook (chapter)

    International Nuclear Information System (INIS)

    The centrifugal shot blaster technology was tested and is being evaluated at Florida International University (FIU) as a baseline technology. In conjunction with FIU's evaluation of efficiency and cost, this report covers the evaluation conducted for safety and health issues. It is a commercially available technology and has been used for various projects at locations throughout the country. The centrifugal shot blaster is an electronically operated shot blast machine that has been modified to remove layers of concrete to varying depths. A hardened steel shot propelled at a high rate of speed abrades the surface of the concrete. The depth of material removed is determined by the rate of speed the machine is traveling and the volume of shot being fired into the blast chamber. The steel shot is recycled and used over until it is pulverized into dust, which ends up in the waste container with the concrete being removed. Debris is continually vacuumed by a large dust collection system attached to the shot blaster. The safety and health evaluation during the human factors assessment focused on two main areas: noise and dust

  4. Scientific Opportunities with the Long-Baseline Neutrino Experiment

    CERN Document Server

    Adams, C; Andrews, M; Anghel, I; Arrieta-Diaz, E; Artuso, M; Asaadi, J; Bai, X; Baird, M; Balantekin, B; Baller, B; Baptista, B; Barker, D; Barletta, W; Barr, G; Bashyal, A; Bass, M; Bellini, V; Berger, B E; Bergevin, M; Berman, E; Berns, H; Bernstein, A; Bernstein, R; Bhatnagar, V; Bhuyan, B; Bishai, M; Blake, A; Blaufuss, E; Bleakley, B; Blucher, E; Blusk, S; Bocean, V; Bolton, T; Breedon, R; Brandt, A; Bromberg, C; Brown, R; Buchanan, N; Bugg, B; Camilleri, L; Carr, R; Carminati, G; Cavanna, F; Chen, A; Chen, H; Chen, K; Cherdack, D; Chi, C; Childress, S; Choudhary, B; Christofferson, C; Church, E; Cline, D; Coan, T; Coelho, J; Coleman, S; Conrad, J; Convery, M; Corey, R; Corwin, L; Davies, G S; Dazeley, S; de Gouvea, A; de Jong, J K; Escobar, C; De, K; Demuth, D; Diwan, M; Djurcic, Z; Dolph, J; Drake, G; Duyang, H; Dye, S; Edmunds, D; Elliott, S; Eno, S; Enomoto, S; Farbin, A; Falk, L; Felde, J; Feyzi, F; Fields, L; Fleming, B; Fowler, J; Fox, W; Friedland, A; Fujikawa, B; Gallagher, H; Gandhi, R; Garvey, G; Gehman, V M; Geronimo, G; Gill, R; Goodman, M C; Goon, J; Graham, M; Gran, R; Grant, C; Greenlee, H; Greenler, L; Guarino, V; Guardincerri, E; Guenette, R; Habib, S; Habig, A; Hackenburg, R W; Hahn, A; Haines, T; Handler, T; Hans, S; Hartnell, J; Harton, J; Hatcher, R; Hatzikoutelis, A; Hays, S; Hazen, E; Headley, M; Heavey, A; Heeger, K; Heise, J; Hellauer, R; Himmel, A; Hogan, M; Holin, A; Horton-Smith, G; Howell, J; Hurh, P; Huston, J; Hylen, J; Imlay, R; Insler, J; Isvan, Z; Jackson, C; Jaffe, D; James, C; Johnson, M; Johnson, R; Johnson, S; Johnston, W; Johnstone, J; Jones, B; Jostlein, H; Junk, T; Kadel, R; Karagiorgi, G; Kaspar, J; Katori, T; Kayser, B; Kearns, E; Keener, P; Kettell, S H; Kirby, M; Klein, J; Koizumi, G; Kopp, S; Kropp, W; Kudryavtsev, V A; Kumar, A; Kumar, J; Kutter, T; Lande, K; Lane, C; Lang, K; Lanni, F; Lanza, R; Latorre, T; La Zia, F; Learned, J; Lee, D; Lee, K; Li, S; Li, Y; Li, Z; Libo, J; Linden, S; Ling, J; Link, J; Littenberg, L; Liu, H; Liu, Q; Liu, T; Losecco, J; Louis, W; Lundberg, B; Lundin, T; Maesano, C; Magill, S; Mahler, G; Malys, S; Mammoliti, F; Mandal, S; Mann, A; Mantsch, P; Marchionni, A; Marciano, W; Mariani, C; Maricic, J; Marino, A; Marshak, M; Marshall, J; Matsuno, S; Mauger, C; Mayer, N; McCluskey, E; McDonald, K; McFarland, K; McKee, D; McKeown, R; McTaggart, R; Mehdiyev, R; Mei, D; Meng, Y; Mercurio, B; Messier, M D; Metcalf, W; Meyhandan, R; Milincic, R; Miller, W; Mills, G; Mishra, S; Sher, S Moed; Mokhov, N; Montanari, D; Moore, C D; Morfin, J; Morse, W; Mufson, S; Muller, D; Musser, J; Naples, D; Napolitano, J; Newcomer, M; Niner, E; Norris, B; Olson, T; Page, B; Pakvasa, S; Paley, J; Palamara, O; Paolone, V; Papadimitriou, V; Park, S; Parsa, Z; Paulos, B; Partyka, K; Pavlovic, Z; Perch, A; Perkin, J D; Peeters, S; Petti, R; Plunkett, R; Polly, C; Pordes, S; Potenza, R; Prakash, A; Prokofiev, O; Perdue, G; Qian, X; Raaf, J L; Radeka, V; Rajendran, R; Rakhno, I; Rameika, R; Ramsey, J; Rebel, B; Rescia, S; Reitzner, D; Richardson, M; Riesselman, K; Robinson, M; Ronquest, M; Rosen, M; Rosenfeld, C; Rucinski, R; Sahijpal, S; Sahoo, H; Samios, N; Sanchez, M C; Schellman, H; Schmitt, R; Schmitz, D; Schneps, J; Scholberg, K; Seibert, S; Shaevitz, M; Shanahan, P; Sharma, R; Shaw, T; Simos, N; Singh, V; Sinnis, G; Sippach, W; Skwarnicki, T; Smy, M; Sobel, H; Soderberg, M; Sondericker, J; Sondheim, W; Spooner, N J C; Stancari, M; Stancu, I; Stefanik, A; Stewart, J; Stone, S; Strait, J; Strait, M; Striganov, S; Sullivan, G; Suter, L; Svoboda, R; Szczerbinska, B; Szydagis, M; Szelc, A; Talaga, R; Tamsett, M; Tariq, S; Tayloe, R; Taylor, C; Taylor, D; Teymourian, A; Themann, H; Thiesse, M; Thomas, J; Thompson, L F; Thomson, M; Thorn, C; Tian, X; Tiedt, D; Toki, W; Tolich, N; Tripathi, M; Tropin, I; Tzanov, M; Urheim, J; Usman, S; Vagins, M; Van Berg, R; Van de Water, R; Varner, G; Vaziri, K; Velev, G; Viren, B; Wachala, T; Wahl, D; Waldron, A; Walter, C W; Wang, H; Wang, W; Warner, D; Wasserman, R; Watson, B; Weber, A; Wei, W; Wendell, R; Wetstein, M; White, A; White, H; Whitehead, L; Whittington, D; Willhite, J; Willis, W; Wilson, R J; Winslow, L; Worcester, E; Wyman, T; Xin, T; Yarritu, K; Ye, J; Yu, J; Yeh, M; Yu, B; Zeller, G; Zhang, C; Zimmerman, E D; Zwaska, R

    2013-01-01

    In this document, we describe the wealth of science opportunities and capabilities of LBNE, the Long-Baseline Neutrino Experiment. LBNE has been developed to provide a unique and compelling program for the exploration of key questions at the forefront of particle physics. Chief among the discovery opportunities are observation of CP symmetry violation in neutrino mixing, resolution of the neutrino mass hierarchy, determination of maximal or near-maximal mixing in neutrinos, searches for nucleon decay signatures, and detailed studies of neutrino bursts from galactic supernovae. To fulfill these and other goals as a world-class facility, LBNE is conceived around four central components: (1) a new, intense wide-band neutrino source at Fermilab, (2) a fine-grained `near' neutrino detector just downstream of the source, (3) the Sanford Underground Research Facility (SURF) in Lead, South Dakota at an optimal distance (~1300 km) from the neutrino source, and (4) a massive liquid argon time-projection chamber (LArTPC...

  5. Status of Development of Antineutrino Detector for Short Baseline Experiment at the HANARO Research Reactor

    International Nuclear Information System (INIS)

    As the burnup proceeds, the neutrino energy spectrum deviates from the initial one. Also the rate of antineutrino production is correlated to the amount of specific fissile elements in the reactor core. By monitoring the antineutrinos during the fission process in the reactor core, scientists can estimate the variation of fissile material. A recent report published by the Department of Safeguards of IAEA also said that a short baseline (SBL) neutrino detector has intrinsic characteristics for monitoring status, operation power and nuclear fuel composition ratio in real time outside the containment building of the nuclear reactor with no-interference mode. Also many reactor neutrino experiments have searched for neutrino flavor oscillation by measuring the electron antineutrinos produced in a nuclear reactor. Since the KamLAND experiments in 2002 gave a precise observation, the neutrino flavor oscillation model has been accepted as an actual phenomenon. One of the interesting issues on reactor neutrino is an anomaly in that an event number of measured neutrinos shows a deficit of 6% compared with the expectation, which means that there should be an undetected sterile neutrino in addition to the known three flavors. It should be created in the flavor oscillations, and does not participate in a weak interaction. The recent high precision and high statistics data from Double Chooz, Daya Bay and RENO experiments may imply this. The research project, which is funded by National Research Foundation of Korea (NRF), started on June, 2012, is developing a short baseline neutrino detector close to the HANARO research reactor, and the technology for reactor monitoring by measuring precisely the neutrino energy spectrum. It is also developing a liquid scintillator containing metals that have large neutron capture cross section, and pulse shape discrimination methods. We will then have a more flexible technology that can detect reactor neutrinos overground. A prototype detector

  6. Status of Development of Antineutrino Detector for Short Baseline Experiment at the HANARO Research Reactor

    Energy Technology Data Exchange (ETDEWEB)

    Sun, Gwangmin; Han, Boyoung; Kim, Hongjoo [KAERI, Daejeon(Korea, Republic of); and others

    2014-05-15

    As the burnup proceeds, the neutrino energy spectrum deviates from the initial one. Also the rate of antineutrino production is correlated to the amount of specific fissile elements in the reactor core. By monitoring the antineutrinos during the fission process in the reactor core, scientists can estimate the variation of fissile material. A recent report published by the Department of Safeguards of IAEA also said that a short baseline (SBL) neutrino detector has intrinsic characteristics for monitoring status, operation power and nuclear fuel composition ratio in real time outside the containment building of the nuclear reactor with no-interference mode. Also many reactor neutrino experiments have searched for neutrino flavor oscillation by measuring the electron antineutrinos produced in a nuclear reactor. Since the KamLAND experiments in 2002 gave a precise observation, the neutrino flavor oscillation model has been accepted as an actual phenomenon. One of the interesting issues on reactor neutrino is an anomaly in that an event number of measured neutrinos shows a deficit of 6% compared with the expectation, which means that there should be an undetected sterile neutrino in addition to the known three flavors. It should be created in the flavor oscillations, and does not participate in a weak interaction. The recent high precision and high statistics data from Double Chooz, Daya Bay and RENO experiments may imply this. The research project, which is funded by National Research Foundation of Korea (NRF), started on June, 2012, is developing a short baseline neutrino detector close to the HANARO research reactor, and the technology for reactor monitoring by measuring precisely the neutrino energy spectrum. It is also developing a liquid scintillator containing metals that have large neutron capture cross section, and pulse shape discrimination methods. We will then have a more flexible technology that can detect reactor neutrinos overground. A prototype detector

  7. Socioeconomic baseline characterization for the Savannah River Plant area

    International Nuclear Information System (INIS)

    This report presents the social and economic characteristics of the environs of the Savannah River Plant (SRP). The characterization is keyed to those areas of the social and economic environment that could be impacted by the construction and operation of major facilities at SRP. The data consists of past trends and existing characteristics of the area's land use; its demographic, social, and economic profile; regional government; community services; housing, transportation; and historical, scenic, and archeological resources. Published documents, reports, and brochures were the primary sources of all the data presented in this document. When current published data was unavailable, representatives of federal, state, and local agencies were contacted by telephone. Conversations were followed by letters of verification, which were reviewed and verified by the agency representative

  8. Hydrogeochemical interpretation of baseline groundwater conditions at the Olkiluoto site

    International Nuclear Information System (INIS)

    Olkiluoto at Eurajoki has been selected as a repository site for final disposal of spent nuclear waste produced on Finland. An understanding of the hydrogeochemical groundwater conditions and evolution is essential in evaluating the long-term safety of the repository. The performance of technical barriers and migration of possibly released radionuclides depend on chemical conditions. A prerequisite for understanding these factors is the ability to specify the water-rock interactions, which control chemical conditions in groundwater. The objective of this study is to interpret the processes and factors, which control the hydrogeochemistry, such as pH and redox conditions. A model of the hydrogeochemical evolution in different parts of the crystalline bedrock at Olkiluoto has been created and the significance of chemical reactions and groundwater mixing along different flow paths calculated. This baseline concept of hydrogeochemistry will perform as a reference in evaluating changes resulting from the ONKALO construction and finally in evaluating hydrogeochemical conditions after the closure of repository. This interpretation and modelling are based on water samples obtained from Baltic sea, precipitation, eight groundwater observation tubes in the overburden, seven shallow boreholes and thirteen deep boreholes in the bedrock for which a comprehensive data set on dissolved chemical species and isotopes was available. Since the previous interpretation report 86 new samples have been collected. Analyses of dissolved gases and fracture calcite and their isotopic measurements were also utilised. The data covers the bedrock at Olkiluoto to a depth of 1000 m. The results from groundwater chemistry, isotopes, petrography, hydrogeology of the site, geomicrobial studies, PCA and speciation calculations were used in the evaluation of evolutionary processes at the site. The geochemical interpretation of water-rock interaction, isotope-chemical evolution and mixing of palaeo

  9. Quality review of hydrochemical baseline data from the Olkiluoto site

    International Nuclear Information System (INIS)

    This report presents a quality evaluation and classification of water samples taken before the end of May 2004, representing the baseline on the Olkiluoto site before construction of ONKALO started. Water samples have been taken from surface waters and from shallow and deep groundwaters to a depth of 1000 m using various sampling techniques. The analysis programme (concise vs. extensive) has varied slightly over the years, depending partly on the samples, their type (surficial water vs. deep groundwater) and the available sample volume. Major ions, pH, redox, temperature, electrical conductivity and salinity (as total dissolved solids, TDS), stable isotopes of water and tritium are generally available for these waters. In addition, environmental isotopes, as well as gases and their isotopes have been analysed for a significant number of samples. Sampling started in the late 1980's. Sampling techniques, chemical analysis methods and detection limits have developed significantly since then, and therefore the quality of the existing data varies. Also, varying hydrological conditions at the groundwater sampling locations complicate evaluation work. The evaluation of data is based on analysing observations of groundwater flow measurements at the sampling locations together with field observations during sampling, and the consistency of chemical analysis results. Comparison with groundwater flow measurements has only been possible for samples from deep boreholes. An integrated and transparent evaluation method suitable for both surface water and groundwater samples has been developed to classify samples according to their representativity and reliability. Samples are graded into four classes; quantitatively (Class B1) and qualitatively (Class B2) reliable samples, samples representing temporary changes on the site due to technical activities in the field (Class T), and clearly uncertain or reference samples (Class E). In addition, the quality of individual chemical

  10. India's baseline plan for nuclear energy self-sufficiency

    International Nuclear Information System (INIS)

    India's nuclear energy strategy has traditionally strived for energy self-sufficiency, driven largely by necessity following trade restrictions imposed by the Nuclear Suppliers Group (NSG) following India's 'peaceful nuclear explosion' of 1974. On September 6, 2008, the NSG agreed to create an exception opening nuclear trade with India, which may create opportunities for India to modify its baseline strategy. The purpose of this document is to describe India's 'baseline plan,' which was developed under constrained trade conditions, as a basis for understanding changes in India's path as a result of the opening of nuclear commerce. Note that this treatise is based upon publicly available information. No attempt is made to judge whether India can meet specified goals either in scope or schedule. In fact, the reader is warned a priori that India's delivery of stated goals has often fallen short or taken a significantly longer period to accomplish. It has been evident since the early days of nuclear power that India's natural resources would determine the direction of its civil nuclear power program. It's modest uranium but vast thorium reserves dictated that the country's primary objective would be thorium utilization. Estimates of India's natural deposits vary appreciably, but its uranium reserves are known to be extremely limited, totaling approximately 80,000 tons, on the order of 1% of the world's deposits; and nominally one-third of this ore is of very low uranium concentration. However, India's roughly 300,000 tons of thorium reserves account for approximately 30% of the world's total. Confronted with this reality, the future of India's nuclear power industry is strongly dependent on the development of a thorium-based nuclear fuel cycle as the only way to insure a stable, sustainable, and autonomous program. The path to India's nuclear energy self-sufficiency was first outlined in a seminal paper by Drs. H. J. Bhabha and N. B. Prasad presented at the Second

  11. Preclinical models for neuroblastoma: establishing a baseline for treatment.

    Directory of Open Access Journals (Sweden)

    Tal Teitz

    Full Text Available BACKGROUND: Preclinical models of pediatric cancers are essential for testing new chemotherapeutic combinations for clinical trials. The most widely used genetic model for preclinical testing of neuroblastoma is the TH-MYCN mouse. This neuroblastoma-prone mouse recapitulates many of the features of human neuroblastoma. Limitations of this model include the low frequency of bone marrow metastasis, the lack of information on whether the gene expression patterns in this system parallels human neuroblastomas, the relatively slow rate of tumor formation and variability in tumor penetrance on different genetic backgrounds. As an alternative, preclinical studies are frequently performed using human cell lines xenografted into immunocompromised mice, either as flank implant or orthtotopically. Drawbacks of this system include the use of cell lines that have been in culture for years, the inappropriate microenvironment of the flank or difficult, time consuming surgery for orthotopic transplants and the absence of an intact immune system. PRINCIPAL FINDINGS: Here we characterize and optimize both systems to increase their utility for preclinical studies. We show that TH-MYCN mice develop tumors in the paraspinal ganglia, but not in the adrenal, with cellular and gene expression patterns similar to human NB. In addition, we present a new ultrasound guided, minimally invasive orthotopic xenograft method. This injection technique is rapid, provides accurate targeting of the injected cells and leads to efficient engraftment. We also demonstrate that tumors can be detected, monitored and quantified prior to visualization using ultrasound, MRI and bioluminescence. Finally we develop and test a "standard of care" chemotherapy regimen. This protocol, which is based on current treatments for neuroblastoma, provides a baseline for comparison of new therapeutic agents. SIGNIFICANCE: The studies suggest that use of both the TH-NMYC model of neuroblastoma and the

  12. Estrogen Receptor α Is Required for Maintaining Baseline Renin Expression.

    Science.gov (United States)

    Lu, Ko-Ting; Keen, Henry L; Weatherford, Eric T; Sequeira-Lopez, Maria Luisa S; Gomez, R Ariel; Sigmund, Curt D

    2016-05-01

    Enzymatic cleavage of angiotensinogen by renin represents the critical rate-limiting step in the production of angiotensin II, but the mechanisms regulating the initial expression of the renin gene remain incomplete. The purpose of this study is to unravel the molecular mechanism controlling renin expression. We identified a subset of nuclear receptors that exhibited an expression pattern similar to renin by reanalyzing a publicly available microarray data set. Expression of some of these nuclear receptors was similarly regulated as renin in response to physiological cues, which are known to regulate renin. Among these, only estrogen receptor α (ERα) and hepatic nuclear factor α have no known function in regulating renin expression. We determined that ERα is essential for the maintenance of renin expression by transfection of small interfering RNAs targeting Esr1, the gene encoding ERα, in renin-expressing As4.1 cells. We also observed that previously characterized negative regulators of renin expression, Nr2f2 and vitamin D receptor, exhibited elevated expression in response to ERα inhibition. Therefore, we tested whether ERα regulates renin expression through an interaction with Nr2f2 and vitamin D receptor. Renin expression did not return to baseline when we concurrently suppressed both Esr1 and Nr2f2 or Esr1 and vitamin D receptor mRNAs, strongly suggesting that Esr1 regulates renin expression independent of Nr2f2 and vitamin D receptor. ERα directly binds to the hormone response element within the renin enhancer region. We conclude that ERα is a previously unknown regulator of renin that directly binds to the renin enhancer hormone response element sequence and is critical in maintaining renin expression in renin-expressing As4.1 cells. PMID:26928806

  13. Long-Term Stewardship Baseline Report and Transition Guidance

    Energy Technology Data Exchange (ETDEWEB)

    Kristofferson, Keith

    2001-11-01

    Long-term stewardship consists of those actions necessary to maintain and demonstrate continued protection of human health and the environment after facility cleanup is complete. As the Department of Energy’s (DOE) lead laboratory for environmental management programs, the Idaho National Engineering and Environmental Laboratory (INEEL) administers DOE’s long-term stewardship science and technology efforts. The INEEL provides DOE with technical, and scientific expertise needed to oversee its long-term environmental management obligations complexwide. Long-term stewardship is administered and overseen by the Environmental Management Office of Science and Technology. The INEEL Long-Term Stewardship Program is currently developing the management structures and plans to complete INEEL-specific, long-term stewardship obligations. This guidance document (1) assists in ensuring that the program leads transition planning for the INEEL with respect to facility and site areas and (2) describes the classes and types of criteria and data required to initiate transition for areas and sites where the facility mission has ended and cleanup is complete. Additionally, this document summarizes current information on INEEL facilities, structures, and release sites likely to enter long-term stewardship at the completion of DOE’s cleanup mission. This document is not intended to function as a discrete checklist or local procedure to determine readiness to transition. It is an overarching document meant as guidance in implementing specific transition procedures. Several documents formed the foundation upon which this guidance was developed. Principal among these documents was the Long-Term Stewardship Draft Technical Baseline; A Report to Congress on Long-Term Stewardship, Volumes I and II; Infrastructure Long-Range Plan; Comprehensive Facility Land Use Plan; INEEL End-State Plan; and INEEL Institutional Plan.

  14. IODINE SALT CONSUMPTION IN INDONESIAN HOUSEHOLDS: BASELINE HEALTH SURVEY 2007

    Directory of Open Access Journals (Sweden)

    Ni Ketut Aryastami

    2012-11-01

    Full Text Available Background: Iodine Deficiency Disorder (100 reduction program has been implemented since 1976. According to the National Economic Survey 2002, the average consumption of iodized salt was 6. 26 grams. The results of Iodine Salt Survey (SGY 2003 showed that the consumption of iodine salt at the household level was 73.2%, meanwhile, the baseline health survey (Riskesdas 2007 showed there was reduction of iodine salt consumption towards 60.2%. Methods: Type of study was secondary data analysis with cross-sectional design utilizing the Riskesdas 2007's data. Sample was selected purposively according to the previous SGY's survey based on the endemically criteria namely highly endemic, mediocre and non endemic. Results: The results of the analysis were there was discrepancy of iodine salt consumption among urban and rural areas as well as mother's education level. The iodine salt consumption was higher in the urban area (65.5% compare to the rural area (52.9%. The higher the education of mothers the better the iodine salt consumed. The usage of iodine salt in the households based on salt quick test was 60.2%, meanwhile, according to the salt titration it was only 23.4%. The results of Excretion Iodine Urine showed that the iodine intake among the school children (age of 6-12 years old was 12.8% and was still below the cut-off point prevalence, which is greater than 50%. The conclusion of this analysisis that there was evidence of iodine salt reduction consumed at the household level. Conversely, there was inclination of the percentage of iodine urine level among the school children in Indonesia in the year 2007. It is recommended that policy analysis need to be conducted due to the achievement of the Universal Salt iodization target, especially in the endemic areas to asses the existence of the IDO prevalence. Key words: Iodine salt at the households, Iodine salt consumption, urine iodine excretion

  15. Baseline and Lifetime Assessments for DC745U Elastomeric Components

    Energy Technology Data Exchange (ETDEWEB)

    Maxwell, R S; Chinn, S C; Herberg, J; Harvey, C; Alviso, C; Vance, A; Cohenour, R; Wilson, M; Solyom, D

    2004-12-20

    The silicone elastomer Dow Corning DC 745U is used in two major components in the W80. We have investigated a number of issues concerning this material. Our studies have accomplished a baseline study of the chemical composition of DC745 and LLNL now has a good understanding of the chemical composition of this material. DC745 crystallizes within the system STS. Two potential means identified to mitigate the risk associated with this phenomenon are to (1) change material formulation and (2) predose the parts to {approx} 25 MRad {gamma}-radiation. A candidate material identified by Gordon Spellman has been studied for composition and the lack of crystallization within the STS has been verified. A sensitivity study of the effects of relevant aging mechanisms also has been performed. The extent of aging due to radiation exposure or elevated temperatures is minimal over the expected course of the LEP. In addition, since the DC745 parts are expected to be replaced at rebuild, the aging clock is essentially being reset. No significant aging issues seem likely to develop for these parts. DC745 parts are also subject to permanent deformation in service. Our studies have shown that the deformation is likely due to incomplete mixing of the raw gum stock and the curing agent at production. This results in areas of low crosslink density that are subject to a higher degree of compression set in service. We have identified two production diagnostic tools based on Nuclear Magnetic Resonance spectroscopy to prescreen the parts at production at KCP. These studies are concluded with specific recommendation for changes to core surveillance for this part based on the chemical knowledge we have gained from this study.

  16. Baseline Profile of Soil Samples from Upian River Watershed

    Directory of Open Access Journals (Sweden)

    Wilanfranco Caballero TAYONE

    2014-06-01

    Full Text Available The Mines and Geosciences Bureau (MGB in the Philippines is currently mapping out the entire Davao City Watershed Area (DCWA. There are 8 major watershed areas within DCWA that has been identified by the MGB and the largest is the Davao River Watershed Area (DRWA. A smaller sub-watershed within DRWA, the Upian River Watershed Area (URWA, was proposed of which its boundary and soil profile is yet to be established. This study focused on the analyses of the soil samples from URWA. The results for pH, organic matter, cation exchange capacity, N, P, K, Ca and Mg were then compared to the Bureau of Soil standard for its fertility rating. Analysis of lead (Pb was also included as a pollutant indicator for possible soil contamination. There are 4 sampling sites with unfavorable ratings for pH, 3 for both organic matter and phosphorus, and 2 stations for both nitrogen and calcium. Fertility rating is generally good for cation exchange capacity, potassium and magnesium. The Bureau of Soil has no existing standards for micronutrients. However, all sampling sites were found to be too low with micronutrients according to Gershuny and Smillie. No indication of lead contamination or pollution on all sites as far as natural levels of lead in surface soil is concerned. This study will provide baseline information that is useful to all stakeholders, to the people living near the area, farmers, planners, and resource managers. This can also provide inputs to key government agencies in the Philippines like the Department of Environment and Natural Resources (DENR and the City Planning Office of Davao in formulating policies for sustainable management of the resource upon implementation of their programs and projects. Without the aforementioned information, planners would have difficulty in predicting the impact or recommend best management strategies for a specific land use.

  17. Strategies for baseline/environmental impact studies in Nigeria

    International Nuclear Information System (INIS)

    This paper reports that in order to assess the environmental impact of site activities and ecosystem change brought about by stress, basic baseline data are necessary to characterize the normal environment so that environmental quality control programs can be developed with a firm ecological base. The program and methodology adopted in our field surveys to assess the character, magnitude and extent of pollutant effects on soil, vegetation and water, as a basis for economic assessment of pollutant effects on agriculture, forestry and the aquatic system and for preparing environmental impact statements, are presented. These techniques were modified and adopted in the environmental impact study of the Isampou Manifold Oil Spill, a study which circumstances made necessary seven years after the oil spill. Reliance on the extent of pollution soon after the incidence was based on the determination of total hydrocarbons at creek bottoms as well as on the determinations of nickel/vanadium ratios. Hydrocarbon contents of creek banks and creek bottoms were within biogenic levels at the time of field sampling. Ni/V ratios were high in heavy impact areas and decreased in areas of medium and very light impact areas. Use of the Ni/V ratio as evidence of past oil pollution agreed closely with a sketch of the extent of crude oil pollution drawn by the Shell Petroleum Development Company seven years earlier. There were nor abnormal vegetation features. The presence of 10-15 years old Musanga cecropioides at the edge of the manifold slot and creeks indicated that vegetation above water level was not affected by the oil spillage. The physico-chemical properties of the waters, plankton composition and density of the species found, as well as the presence of endroproct bryozoan in the benthos showed that the aquatic system had by the time of sample collection, completely recovered from the oil spillage

  18. Performance-based waste acceptance criteria preliminary baseline assumptions

    International Nuclear Information System (INIS)

    The Department of Energy's (DOE's) strategy for the management of transuranic (TRU) and TRU mixed wastes has focused on the development of the Waste Isolation Pilot Plant (WIPP). The WIPP repository is designated to receive DOE defense wastes that meet the established criteria for acceptance. As a national strategy [DOE, 1993], DOE does not intend to treat candidate wastes unless treatment or processing are necessary to meet the safety, health, and regulatory criteria for transport and disposal at WIPP. The WIPP WAC has evolved over the past 10 years to include criteria and requirements in support of the Waste Characterization program and other related compliance programs. In aggregate, the final health, safety and regulatory criteria for the waste will be documented in the Disposal WAC. This document serves two purposes. First, it familiarizes regulators and stakeholders with the concept of performance based waste acceptance criteria as an augmentation within a final Waste Isolation Pilot Plant (WIPP) Waste Acceptance Criteria. Second, the document preliminarily identifies certain waste characteristics that appear important to the performance assessment process for WIPP; therefore, these could become component characteristics in the Performance Based Waste Acceptance Criteria (PBWAC). Identification of the final PBWAC will be accomplished through iterative runs of the System Prioritization Method (SPM). These iterations will serve to more clearly isolate and identify those waste characteristics that directly and predominately impact on the performance assessment

  19. Effects of Baseline Selection on Magnetocardiography: P-Q and T-P Intervals

    Energy Technology Data Exchange (ETDEWEB)

    Lim, Hyun Kyoon; Kwon, Hyuk Chan; Kim, Tae En; Lee, Yong Ho; Kim, Jin Mok; Kim, In Seon; Kim, Ki Woong; Park, Yong Ki [Korea Research Institute of Standards and Science, Daejeon (Korea, Republic of)

    2007-10-15

    The baseline selection is the first and important step to analyze magnetocardiography (MCG) parameters. There are no difficulties to select the baseline between P- and Q-wave peak (P-Q interval) of MCG wave recorded from healthy subjects because the P-Q intervals of the healthy subjects do not much vary. However, patients with ischemic heart disease often show an unstable P-Q interval which does not seem to be appropriate for the baseline. In this case, T-P interval is alternatively recommended for the baseline. However, there has been no study on the difference made by the baseline selection. In this study, we studied the effect of the different baseline selection. MCG data were analyzed from twenty healthy subjects and twenty one patients whose baselines were alternatively selected in the T-P interval for their inappropriate P-Q interval. Paired T-test was used to compare two set of data. Fifteen parameters derived from the R-wave peak, the T-wave peak, and the period, T{sub max/3} ∼ T{sub max} were compared for the different baseline selection. As a result, most parameters did not show significant differences (p>0.05) except few parameters. Therefore, there will be no significant differences if anyone of two intervals were selected for the MCG baseline. However, for the consistent analysis, P-Q interval is strongly recommended for the baseline correction.

  20. A model-free, fully automated baseline-removal method for Raman spectra.

    Science.gov (United States)

    Schulze, H Georg; Foist, Rod B; Okuda, Kadek; Ivanov, André; Turner, Robin F B

    2011-01-01

    We present here a fully automated spectral baseline-removal procedure. The method uses a large-window moving average to estimate the baseline; thus, it is a model-free approach with a peak-stripping method to remove spectral peaks. After processing, the baseline-corrected spectrum should yield a flat baseline and this endpoint can be verified with the χ(2)-statistic. The approach provides for multiple passes or iterations, based on a given χ(2)-statistic for convergence. If the baseline is acceptably flat given the χ(2)-statistic after the first pass at correction, the problem is solved. If not, the non-flat baseline (i.e., after the first effort or first pass at correction) should provide an indication of where the first pass caused too much or too little baseline to be subtracted. The second pass thus permits one to compensate for the errors incurred on the first pass. Thus, one can use a very large window so as to avoid affecting spectral peaks--even if the window is so large that the baseline is inaccurately removed--because baseline-correction errors can be assessed and compensated for on subsequent passes. We start with the largest possible window and gradually reduce it until acceptable baseline correction based on the χ(2) statistic is achieved. Results, obtained on both simulated and measured Raman data, are presented and discussed. PMID:21211157

  1. Factors Influencing Depression Endpoints Research (FINDER: baseline results of Italian patients with depression

    Directory of Open Access Journals (Sweden)

    Grassi Luigi

    2009-05-01

    Full Text Available Abstract Background Factors Influencing Depression Endpoints Research (FINDER is a 6-month, prospective, observational study carried out in 12 European countries aimed at investigating health-related quality of life (HRQoL in outpatients receiving pharmacological treatment for a first or new depressive episode. Baseline characteristics of patients enrolled in Italy are presented. Methods All treatment decisions were at the discretion of the investigator. Data were collected at baseline and after 3 and 6 months of treatment. Baseline evaluations included demographics, medical and psychiatric history, and medications used in the last 24 months and prescribed at enrolment. The Hospital Anxiety and Depression Scale (HADS, was adopted to evaluate depressive symptoms, while somatic and painful physical symptoms were assessed by using the Somatic Symptom Inventory (SSI and a 0 to 100 mm visual analogue scale (VAS, HRQoL via 36-item Short Form Health Survey (SF-36, and the European Quality of Life 5-Dimensions (EQ-5D instrument. Results A total of 513 patients were recruited across 38 sites. The mean ± standard deviation (SD age at first depressive episode was 38.7 ± 15.9 years, the mean duration of depression 10.6 ± 12.3 years. The most common psychiatric comorbidities in the previous 24 months were anxiety/panic (72.6% and obsessive/compulsive disorders (13.4%, while 35.9% had functional somatic syndromes. Most patients (65.1% reported pain from any cause. Monotherapy with selective serotonin reuptake inhibitors (SSRIs and tricyclic antidepressants (TCAs was prescribed at enrolment in 64.5% and 6.4% of the cases, respectively. The most commonly prescribed agents were sertraline (17.3%, escitalopram (16.2%, venlaflaxine (15.6% and paroxetine (14.8%. The mean HADS subscores for depression and anxiety were 13.3 ± 4.2 and 12.2 ± 3.9, respectively; 76.4% of patients could be defined as being 'probable cases' for depression and 66.2% for anxiety. The

  2. Simple and robust baseline estimation method for multichannel SAR-GMTI systems

    Science.gov (United States)

    Chen, Zhao-Yan; Wang, Tong; Ma, Nan

    2016-07-01

    In this paper, the authors propose an approach of estimating the effective baseline for ground moving target indication (GMTI) mode of synthetic aperture radar (SAR), which is different from any previous work. The authors show that the new method leads to a simpler and more robust baseline estimate. This method employs a baseline search operation, where the degree of coherence (DOC) is served as a metric to judge whether the optimum baseline estimate is obtained. The rationale behind this method is that the more accurate the baseline estimate, the higher the coherence of the two channels after co-registering with the estimated baseline value. The merits of the proposed method are twofold: simple to design and robust to the Doppler centroid estimation error. The performance of the proposed method is good. The effectiveness of the method is tested with real SAR data.

  3. Updated neutron spectrum characterization of SNL baseline reactor environments

    International Nuclear Information System (INIS)

    The neutron spectrum characteristics of the primary reactor environments are defined for use by facility customers and to provide an audit trail in support of current quality assurance initiatives. The neutron and gamma environments in the four primary customer environments at SPR-III and ACRR facilities are characterized in detail. Enough detail is provided on other frequently-used environments to support the definition of the 3-MeV and 1-MeV(Si) fluence provided on the Radiation Metrology Laboratory dosimetry reports

  4. Re-Creating Missing Population Baselines for Pacific Reef Sharks

    Science.gov (United States)

    Nadon, Marc O; Baum, Julia K; Williams, Ivor D; Mcpherson, Jana M; Zgliczynski, Brian J; Richards, Benjamin L; Schroeder, Robert E; Brainard, Russell E

    2012-01-01

    Summary Abstract Sharks and other large predators are scarce on most coral reefs, but studies of their historical ecology provide qualitative evidence that predators were once numerous in these ecosystems. Quantifying density of sharks in the absence of humans (baseline) is, however, hindered by a paucity of pertinent time-series data. Recently researchers have used underwater visual surveys, primarily of limited spatial extent or nonstandard design, to infer negative associations between reef shark abundance and human populations. We analyzed data from 1607 towed-diver surveys (>1 ha transects surveyed by observers towed behind a boat) conducted at 46 reefs in the central-western Pacific Ocean, reefs that included some of the world's most pristine coral reefs. Estimates of shark density from towed-diver surveys were substantially lower (base) es obstaculizada por la falta de datos de series de tiempo pertinentes. Recientemente, los investigadores han utilizado muestreos visuales submarinos, de extensión espacial limitada o de diseño no estándar, para inferir asociaciones negativas entre la abundancia de tiburones de arrecife y las poblaciones humanas. Analizamos datos de 1607 muestreos por remolque de buzos (transectos >1ha muestreados por observadores remolcados por una lancha) realizados en 46 arrecifes en el Océano Pacífico centro-occidental, arrecifes que incluyeron algunos de los más prístinos del mundo. Las estimaciones de densidad de tiburones fue sustancialmente menor (<10%) que estimaciones publicadas a partir de muestreos a lo largo de transectos pequeños (<0.02 ha), lo cual no es consistente con las pirámides de biomasa invertidas (la biomasa de depredadores es mayor que la biomasa de presas) reportadas para arrecifes prístinos por otros autores. Examinamos la relación entre la densidad de tiburones de arrecife observados en los muestreos por remolque de buzos y la población humana en modelos y consideramos la influencia de la productividad

  5. CDD (Community Driven Development) and Social Capital Impact : Designing a Baseline Survey in the Philippines

    OpenAIRE

    World Bank

    2005-01-01

    The baseline survey of the KALAHI-CIDSS project in the Philippines is an attempt to generate such insights and strengthen learning about CDD programs through rigorous evaluations. This evaluation follows the "good practices" prescribed by experts in that it collects quality baseline data in a representative sample of both intervention groups and matched comparison groups. This baseline survey not only provides valuable information about the KALAHI-CIDSS project, but also offers some guidance ...

  6. Very long baseline interferometry applied to polar motion, relativity, and geodesy. Ph.D. thesis

    International Nuclear Information System (INIS)

    The causes and effects of diurnal polar motion are described. An algorithm was developed for modeling the effects on very long baseline interferometry observables. A selection was made between two three-station networks for monitoring polar motion. The effects of scheduling and the number of sources observed on estimated baseline errors are discussed. New hardware and software techniques in very long baseline interferometry are described

  7. Baseline adaptive Kalman filter estimation method for nuclear radiation pulse height analysis

    International Nuclear Information System (INIS)

    To estimate the baseline of sampled pulse signal serial and then complete the analysis of the nuclear radiation pulse height, the present study concerns in baseline adaptive kalman filtering estimation method. The present study concerns in the application effect of using adaptive kalman filtering estimation method to establish the mathematical model and then estimate the baseline. The validity of this method was certified by experiment, this method is an effective way of data pretreatment for the pulse shaping and so on. (authors)

  8. Cape Canaveral Air Force Station integrated resource assessment. Volume 2, Baseline detail

    Energy Technology Data Exchange (ETDEWEB)

    Wahlstrom, R.R.; McMordie, K.L.; Parker, S.A.; King, D.A.; Sandusky, W.F.

    1993-12-01

    The US Air Force (USAF) has tasked the Pacific Northwest Laboratory (PNL), in support of the US Department of Energy (DOE) Federal Energy Management Program (FEMP), to assess energy use at Cape Canaveral Air Force Station (AFS). The information obtained from this assessment will be used in identifying energy resource opportunities to reduce overall energy consumption by the station. The primary focus of this report is to assess the current baseline energy consumption at Cape Canaveral AFS. It is A companion report to Volume 1, the Executive Summary, and Volume 3, the Resource Assessment. This assessment requires that information be obtained and characterized for buildings, utilities, energy sources, energy uses, and load profiles to be used to improve the current energy system on the station. The characteristics of electricity, diesel fuel, No. 2 fuel oil, and motor vehicle gasoline (MOGAS) are analyzed for on-base facilities. The assessment examines basic regional information used to determine energy-use intensity (EUI) values for Cape Canaveral AFS facilities by building, fuel type, and energy end use. It also provides a summary of electricity consumption from Florida Power and Light Company (FPL) metered data for 1985--1991. Load profile information obtained from FPL data is presented for the North, South, and Titan Substations for the four seasons of the year, including weekdays and weekends.

  9. Development of a gadolinium-loaded liquid scintillator for the Hanaro short baseline prototype detector

    International Nuclear Information System (INIS)

    We propose a new experiment on the site of the Korea Atomic Energy Research Institute (KAERI) located at Daejeon, Korea. The Hanaro short baseline (SBL) nuclear reactor with a thermal power output 30 MW is used to investigate a reactor neutrino anomaly. A Hanaro SBL prototype detector having a 60-l volume has been constructed ∼6 m away from the reactor core. A gadolinium (Gd)-loaded liquid scintillator (LS) is used as an active material to trigger events. The selection of the LS is guided by physical and technical requirements, as well as safety considerations. A linear alkyl benzene (LAB) is used as a base solvent of the Hanaro SBL prototype detector. Three g/l of PPO and 30 mg/l of bis-MSB are dissolved to formulate the LAB-based LS. Then, a 0.5% gadolinium (Gd) complex with carboxylic acid is loaded into the LAB-based LS by using the liquid - liquid extraction method. In this paper, we will summarize all the characteristics of the Gd-loaded LAB-based LS for the Hanaro prototype detector.

  10. The transliminal brain at rest: baseline EEG, unusual experiences, and access to unconscious mental activity.

    Science.gov (United States)

    Fleck, Jessica I; Green, Deborah L; Stevenson, Jennifer L; Payne, Lisa; Bowden, Edward M; Jung-Beeman, Mark; Kounios, John

    2008-01-01

    Transliminality reflects individual differences in the threshold at which unconscious processes or external stimuli enter into consciousness. Individuals high in transliminality possess characteristics such as magical ideation, belief in the paranormal, and creative personality traits, and also report the occurrence of manic/mystic experiences. The goal of the present research was to determine if resting brain activity differs for individuals high versus low in transliminality. We compared baseline EEG recordings (eyes-closed) between individuals high versus low in transliminality, assessed using The Revised Transliminality Scale of Lange et al. (2000). Identifying reliable differences at rest between high- and low-transliminality individuals would support a predisposition for transliminality-related traits. Individuals high in transliminality exhibited lower alpha, beta, and gamma power than individuals low in transliminality over left posterior association cortex and lower high alpha, low beta, and gamma power over the right superior temporal region. In contrast, when compared to individuals low in transliminality, individuals high in transliminality exhibited greater gamma power over the frontal-midline region. These results are consistent with prior research reporting reductions in left temporal/parietal activity, as well as the desynchronization of right temporal activity in schizotypy and related schizophrenia spectrum disorders. Further, differences between high- and low-transliminality groups extend existing theories linking altered hemispheric asymmetries in brain activity to a predisposition toward schizophrenia, paranormal beliefs, and unusual experiences. PMID:18814870

  11. Development of a gadolinium-loaded liquid scintillator for the Hanaro short baseline prototype detector

    Science.gov (United States)

    Yeo, In Sung; Joo, Kyung Kwang; So, Sun Heang; Song, Sook Hyung; Kim, Hong Joo; So, Jung Ho; Park, Kang Soon; Ma, Kyung Ju; Jeon, Eun Ju; Kim, Jin Yu; Kim, Young Duk; Lee, Jason; Lee, Jeong-Yeon; Sun, Gwang-Min

    2014-02-01

    We propose a new experiment on the site of the Korea Atomic Energy Research Institute (KAERI) located at Daejeon, Korea. The Hanaro short baseline (SBL) nuclear reactor with a thermal power output 30 MW is used to investigate a reactor neutrino anomaly. A Hanaro SBL prototype detector having a 60- l volume has been constructed ˜6 m away from the reactor core. A gadolinium (Gd)-loaded liquid scintillator (LS) is used as an active material to trigger events. The selection of the LS is guided by physical and technical requirements, as well as safety considerations. A linear alkyl benzene (LAB) is used as a base solvent of the Hanaro SBL prototype detector. Three g/ l of PPO and 30 mg/ l of bis-MSB are dissolved to formulate the LAB-based LS. Then, a 0.5% gadolinium (Gd) complex with carboxylic acid is loaded into the LAB-based LS by using the liquidliquid extraction method. In this paper, we will summarize all the characteristics of the Gd-loaded LAB-based LS for the Hanaro prototype detector.

  12. Development of a gadolinium-loaded liquid scintillator for the Hanaro short baseline prototype detector

    Energy Technology Data Exchange (ETDEWEB)

    Yeo, In Sung; Joo, Kyung Kwang; So, Sun Heang [Chonnam National University, Gwangju (Korea, Republic of); and others

    2014-02-15

    We propose a new experiment on the site of the Korea Atomic Energy Research Institute (KAERI) located at Daejeon, Korea. The Hanaro short baseline (SBL) nuclear reactor with a thermal power output 30 MW is used to investigate a reactor neutrino anomaly. A Hanaro SBL prototype detector having a 60-l volume has been constructed ∼6 m away from the reactor core. A gadolinium (Gd)-loaded liquid scintillator (LS) is used as an active material to trigger events. The selection of the LS is guided by physical and technical requirements, as well as safety considerations. A linear alkyl benzene (LAB) is used as a base solvent of the Hanaro SBL prototype detector. Three g/l of PPO and 30 mg/l of bis-MSB are dissolved to formulate the LAB-based LS. Then, a 0.5% gadolinium (Gd) complex with carboxylic acid is loaded into the LAB-based LS by using the liquid - liquid extraction method. In this paper, we will summarize all the characteristics of the Gd-loaded LAB-based LS for the Hanaro prototype detector.

  13. The full potential of the baseline SASE undulators of the European XFEL

    International Nuclear Information System (INIS)

    The output SASE characteristics of the baseline European XFEL, recently used in the TDRs of scientific instruments and X-ray optics, have been previously optimized assuming uniform undulators without considering the potential of undulator tapering in the SASE regime. Here we demonstrate that the performance of European XFEL sources can be significantly improved without additional hardware. The procedure simply consists in the optimization of the undulator gap configuration for each X-ray beamline. Here we provide a comprehensive description of the soft X-ray photon beam properties as a function of wavelength and bunch charge. Based on nominal parameters for the electron beam, we demonstrate that undulator tapering allows one to achieve up to a tenfold increase in peak power and photon spectral density in the conventional SASE regime. We illustrate this fact for the SASE3 beamline. The FEL code Genesis has been extensively used for these studies. Based on these findings we suggest that the requirements for the SASE3 instrument (SCS, SQS) and for the SASE3 beam transport system be updated.

  14. Baseline public health assessment for CERCLA investigations at the LLNL Livermore Site

    Energy Technology Data Exchange (ETDEWEB)

    Layton, D.W.; Daniels, J.I.; Isherwood, W.I. (eds.); Bogen, K.T.; Cederwall, R.T.; Daniels, J.I.; Goyal, K.; Hall, C.H.; Hall, L.C.; Johnson, V.M.; Layton, D.W.; Mallon, B.J.; McKone, T.E.; Rice, D.W. Jr.; Thorpe, R.K.; Tompson, A.F.B. (Lawrence Livermore National Lab., CA (United States)); Dresen, M.D.; McKereghan, P.F.; Nichols, E.M.; Small, M.C.; Yukic, F.S. (Weiss Associates, Emeryville, CA (United States))

    1990-09-30

    In 1987, the US Environmental Protection Agency (EPA) added the Lawrence Livermore National Laboratory (LLNL) Livermore site to the National Priorities List (NPL) due to volatile organic compounds (VOCs) found by LLNL in ground water onsite and offsite. One key component of the site cleanup effort at a NPL or Superfund site is the Remedial Investigation (RI), which includes studies and monitoring programs to acquire and analyze pertinent site-related data, such as the nature and extent of contamination and the characteristics of the local hydrogeology. An important part of the RI is the Baseline Public Health Assessment (BPHA), which addresses the potential future public health risks that could exist if no cleanup is attempted. This BPHA material was included in the RI for the LLNL Livermore site, which was submitted to regulatory agencies in May 1990. The BPHA is published here as a stand-alone document for the convenience of those interested only in this material. Because of the US Department of Energy (DOE), LLNL and environmental regulatory agencies are dedicated to the remediation of contaminated soils, sediments, and ground water at the Livermore site, the potential risks described herein are unlikely to occur. This BPHA provides the information needed to evaluate the benefits of cleanup alternatives. 166 refs., 49 figs., 35 tabs.

  15. Spent nuclear fuel technical baseline description, Fiscal Year 1996: Volume II, supporting data

    International Nuclear Information System (INIS)

    The Technical Baseline Description documents the Project-Level functions and requirements, along with associated enabling assumptions, issues, trade studies, interfaces, and products. It is a snapshot in time of the baseline at the beginning of September 1995. It supports the individual subprojects in the development of lower-tier functions, requirements, and specifications in FY 1996. It also supports the need for Hanford site planning to be based on an integrated Hanford site systems engineering technical baseline; and is traceable to that baseline. This document replaces and supercedes WHC-SD-SNF-SD-003

  16. COMBINED GPS/GLONASS PRECISE POSITIONING FOR LONG-DISTANCE BASELINES

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Combined GPS/GLONASS can increase the accuracy and reliability ofpositioning especially in some applications with many impediments.Due to the atmosphere delay,the commonly used methods for processing short distance baselines can not be implemented in long distance baselines.In this paper,a new data processing strategy for long distance baselines is proposed,which uses the properties of some combination observables of combined GPS/GLONASS and distance baselines may come to the order of 10-8 and combined GPS/GLONASS improves the accuracy over that of GPS-only positioning,which brings benefit to crust deformation monitoring and research on geodynamics.

  17. Two baselines are better than one: Improving the reliability of computerized testing in sports neuropsychology.

    Science.gov (United States)

    Bruce, Jared; Echemendia, Ruben; Tangeman, Lindy; Meeuwisse, Willem; Comper, Paul; Hutchison, Michael; Aubry, Mark

    2016-01-01

    Computerized neuropsychological tests are frequently used to assist in return-to-play decisions following sports concussion. However, due to concerns about test reliability, the Centers for Disease Control and Prevention recommends yearly baseline testing. The standard practice that has developed in baseline/postinjury comparisons is to examine the difference between the most recent baseline test and postconcussion performance. Drawing from classical test theory, the present study investigated whether temporal stability could be improved by taking an alternate approach that uses the aggregate of 2 baselines to more accurately estimate baseline cognitive ability. One hundred fifteen English-speaking professional hockey players with 3 consecutive Immediate Postconcussion Assessment and Testing (ImPACT) baseline tests were extracted from a clinical program evaluation database overseen by the National Hockey League and National Hockey League Players' Association. The temporal stability of ImPACT composite scores was significantly increased by aggregating test performance during Sessions 1 and 2 to predict performance during Session 3. Using this approach, the 2-factor Memory (r = .72) and Speed (r = .79) composites of ImPACT showed acceptable long-term reliability. Using the aggregate of 2 baseline scores significantly improves temporal stability and allows for more accurate predictions of cognitive change following concussion. Clinicians are encouraged to estimate baseline abilities by taking into account all of an athlete's previous baseline scores. PMID:26786726

  18. Factors Associated With Non-participation in a Face-to-Face Second Survey Conducted 5 Years After the Baseline Survey

    OpenAIRE

    ,

    2015-01-01

    Background Non-participation in second surveys is reported to be associated with certain baseline characteristics; however, such data are unavailable for Japanese populations. Although disease incidence during follow-up might influence participation, few reports have addressed this possibility. This study sought to identify factors associated with non-participation in a second survey of a population-based cohort, and to evaluate the influence of self-reported disease incidence on non-particip...

  19. Glycated Hemoglobin, Fasting Insulin and the Metabolic Syndrome in Males. Cross-Sectional Analyses of the Aragon Workers’ Health Study Baseline

    OpenAIRE

    Saravia, Gabriela; Civeira, Fernando; Hurtado-Roca, Yamilee; Andres, Eva; Leon, Montserrat; Pocovi, Miguel; Ordovas, Jose; Guallar, Eliseo; Fernandez-Ortiz, Antonio; Casasnovas, Jose Antonio; Laclaustra, Martin

    2015-01-01

    Background and Aims Glycated hemoglobin (HbA1c) is currently used to diagnose diabetes mellitus, while insulin has been relegated to research. Both, however, may help understanding the metabolic syndrome and profiling patients. We examined the association of HbA1c and fasting insulin with clustering of metabolic syndrome criteria and insulin resistance as two essential characteristics of the metabolic syndrome. Methods We used baseline data from 3200 non-diabetic male participants in the Arag...

  20. Baseline effects on carbon footprints of biofuels: The case of wood

    International Nuclear Information System (INIS)

    As biofuel usage has boomed over the past decade, so has research and regulatory interest in its carbon accounting. This paper examines one aspect of that carbon accounting: the baseline, i.e. the reference case against which other conditions or changes can be compared. A literature search and analysis identified four baseline types: no baseline; reference point; marginal fossil fuel; and biomass opportunity cost. The fourth one, biomass opportunity cost, is defined in more detail, because this is not done elsewhere in the literature. The four baselines are then applied to the carbon footprint of a wood-fired power plant. The footprint of the resulting wood-fired electricity varies dramatically, according to the type of baseline. Baseline type is also found to be the footprint's most significant sensitivity. Other significant sensitivities are: efficiency of the power plant; the growth (or re-growth) rate of the forest that supplies the wood; and the residue fraction of the wood. Length of the policy horizon is also an important factor in determining the footprint. The paper concludes that because of their significance and variability, baseline choices should be made very explicit in biofuel carbon footprints. - Highlights: ► Four baseline types for biofuel footprinting are identified. ► One type, ‘biomass opportunity cost’, is defined mathematically and graphically. ► Choice of baseline can dramatically affect the footprint result. ► The ‘no baseline approach is not acceptable. ► Choice between the other three baselines depends on the question being addressed.

  1. Molecular markers of anti-malarial drug resistance in Lahj Governorate, Yemen: baseline data and implications

    Directory of Open Access Journals (Sweden)

    Chance Michael L

    2011-08-01

    Full Text Available Abstract Background This is an investigation of anti-malarial molecular markers coupled with a therapeutic efficacy test of chloroquine (CQ against falciparum malaria in an area of unstable malaria in Lahj Governorate, Yemen. The study was aimed at assessment of therapeutic response to CQ and elucidation of baseline information on molecular markers for Plasmodium falciparum resistance against CQ and sulphadoxine/pyrimethamine (SP. Methods Between 2002 and 2003 the field test was conducted according to the standard WHO protocol to evaluate the therapeutic efficacy of CQ in 124 patients with falciparum malaria in an endemic area in Lahj Governorate in Yemen. Blood samples collected during this study were analysed for P. falciparum chloroquine resistance transporter gene (pfcrt-76 polymorphisms, mutation pfcrt-S163R and the antifolate resistance-associated mutations dihydrofolate reductase (dhfr-C59R and dihydropteroate synthase (dhps-K540E. Direct DNA sequencing of the pfcrt gene from three representative field samples was carried out after DNA amplification of the 13 exons of the pfcrt gene. Results Treatment failure was detected in 61% of the 122 cases that completed the 14-day follow-up. The prevalence of mutant pfcrt T76 was 98% in 112 amplified pre-treatment samples. The presence of pfcrt T76 was poorly predictive of in vivo CQ resistance (PPV = 61.8%, 95% CI = 52.7-70.9. The prevalence of dhfr Arg-59 mutation in 99 amplified samples was 5%, while the dhps Glu-540 was not detected in any of 119 amplified samples. Sequencing the pfcrt gene confirmed that Yemeni CQ resistant P. falciparum carry the old world (Asian and African CQ resistant haplotype CVIETSESI at positions 72,73,74,75,76,220,271, 326 and 371. Conclusion This is the first study to report baseline information on the characteristics and implications of anti-malarial drug resistance markers in Yemen. It is also the first report of the haplotype associated with CQR P. falciparum

  2. Implementation of interval walking training in patients with type 2 diabetes in Denmark: rationale, design, and baseline characteristics

    Directory of Open Access Journals (Sweden)

    Ried-Larsen M

    2016-06-01

    Full Text Available Mathias Ried-Larsen,1–3 Reimar W Thomsen,2,4 Klara Berencsi,4 Cecilie F Brinkløv,1,5 Charlotte Brøns,1,5 Laura S Valentiner,1,6 Kristian Karstoft,1,3 Henning Langberg,1,6 Allan A Vaag,1,2,5 Bente K Pedersen,1,3 Jens S Nielsen7 1Department of Infectious Diseases, Centre for Physical Activity Research, Rigshospitalet, University of Copenhagen, Copenhagen, 2The Danish Diabetes Academy, Odense University Hospital, Odense, 3Department of Infectious Diseases, Centre of Inflammation and Metabolism, Rigshospitalet, University of Copenhagen, Copenhagen, 4Department of Clinical Epidemiology, Aarhus University Hospital, Aarhus Nord, 5Department of Endocrinology (Diabetes and Metabolism, Rigshospitalet, University of Copenhagen, 6CopenRehab, Department of Public Health, Section of Social Medicine, University of Copenhagen, Copenhagen, 7Department of Endocrinology, Odense University Hospital, Odense, Denmark Abstract: Promoting physical activity is a first-line choice of treatment for patients with type 2 diabetes (T2D. However, there is a need for more effective tools and technologies to facilitate structured lifestyle interventions and to ensure a better compliance, sustainability, and health benefits of exercise training in patients with T2D. The InterWalk initiative and its innovative application (app for smartphones described in this study were developed by the Danish Centre for Strategic Research in T2D aiming at implementing, testing, and validating interval walking in patients with T2D in Denmark. The interval walking training approach consists of repetitive 3-minute cycles of slow and fast walking with simultaneous intensity guiding, based on the exercise capacity of the user. The individual intensity during slow and fast walking is determined by a short initial self-conducted and audio-guided fitness test, which combined with automated audio instructions strives to motivate the individual to adjust the intensity to the predetermined individualized walking intensities. The InterWalk app data are collected prospectively from all users and will be linked to the unique Danish nationwide databases and administrative registries, allowing extensive epidemiological studies of exercise in patients with T2D, such as the level of adherence to InterWalk training and long-term effectiveness surveys of important health outcomes, including cardiovascular morbidity and mortality. Currently, the InterWalk app has been downloaded by >30,000 persons, and the achieved epidemiological data quality is encouraging. Of the 9,466 persons providing personal information, 80% of the men and 62% women were overweight or obese (body mass index ≥25. The InterWalk project represents a contemporary technology-driven public health approach to monitor real-life exercise adherence and to propagate improved health through exercise intervention in T2D and in the general population. Keywords: exercise, telemedicine, cell phones

  3. Baseline characteristics of the 4011 patients recruited into the 'Efficacy of Nitric Oxide in Stroke' (ENOS) trial

    OpenAIRE

    Bath, Philip M. W.; Adami, Alessandro; Bereczki, Daniel; Berge, Eivind; Beridze, Maia; Cala, Lesley; Casado, Ana; Caso, Valeria; Chang, Hui Meng; Christensen, Hanne; Collins, Ronan; Czlonkowska, Anna; Dineen, Robert A; El Etribi, Anwar; Ghani, Abdul Rahman

    2014-01-01

    Background High blood pressure is common in acute stroke and associated with a worse functional outcome. Many patients who present with acute stroke are taking prescribed antihypertensive therapy before their stroke.Aims ENOS tested whether lowering blood pressure and continuing pre-stroke antihypertensive therapy are each safe and effective.Methods This study is an international multi-centre prospective randomized single-blind blinded-endpoint parallel-group partial-factorial controlled tria...

  4. Rationale, design, and baseline characteristics of a randomized, placebo-controlled cardiovascular outcome trial of empagliflozin (EMPA-REG OUTCOME™)

    OpenAIRE

    Zinman, Bernard; Inzucchi, Silvio E.; Lachin, John M.; Wanner, Christoph; Ferrari, Roberto; Fitchett, David; Bluhmki, Erich; Hantel, Stefan; Kempthorne-Rawson, Joan; Newman, Jennifer; Johansen, Odd Erik; Woerle, Hans-Juergen; Broedl, Uli C.

    2014-01-01

    Background Evidence concerning the importance of glucose lowering in the prevention of cardiovascular (CV) outcomes remains controversial. Given the multi-faceted pathogenesis of atherosclerosis in diabetes, it is likely that any intervention to mitigate this risk must address CV risk factors beyond glycemia alone. The SGLT-2 inhibitor empagliflozin improves glucose control, body weight and blood pressure when used as monotherapy or add-on to other antihyperglycemic agents in patients with ty...

  5. Design, rationale, and baseline characteristics of a cluster randomized controlled trial of pay for performance for hypertension treatment: study protocol

    Directory of Open Access Journals (Sweden)

    Lutschg Meghan Z

    2011-10-01

    Full Text Available Abstract Background Despite compelling evidence of the benefits of treatment and well-accepted guidelines for treatment, hypertension is controlled in less than one-half of United States citizens. Methods/design This randomized controlled trial tests whether explicit financial incentives promote the translation of guideline-recommended care for hypertension into clinical practice and improve blood pressure (BP control in the primary care setting. Using constrained randomization, we assigned 12 Veterans Affairs hospital outpatient clinics to four study arms: physician-level incentive; group-level incentive; combination of physician and group incentives; and no incentives (control. All participants at the hospital (cluster were assigned to the same study arm. We enrolled 83 full-time primary care physicians and 42 non-physician personnel. The intervention consisted of an educational session about guideline-recommended care for hypertension, five audit and feedback reports, and five disbursements of incentive payments. Incentive payments rewarded participants for chart-documented use of guideline-recommended antihypertensive medications, BP control, and appropriate responses to uncontrolled BP during a prior four-month performance period over the 20-month intervention. To identify potential unintended consequences of the incentives, the study team interviewed study participants, as well as non-participant primary care personnel and leadership at study sites. Chart reviews included data collection on quality measures not related to hypertension. To evaluate the persistence of the effect of the incentives, the study design includes a washout period. Discussion We briefly describe the rationale for the interventions being studied, as well as the major design choices. Rigorous research designs such as the one described here are necessary to determine whether performance-based payment arrangements such as financial incentives result in meaningful quality improvements. Trial Registration http://www.clinicaltrials.govNCT00302718

  6. Design, methods, baseline characteristics and interim results of the Catheter Sampled Blood Archive in Cardiovascular Diseases (CASABLANCA study

    Directory of Open Access Journals (Sweden)

    Hanna K. Gaggin

    2014-11-01

    Conclusions: The CASABLANCA study will examine the role of novel biomarkers and metabolomics for predicting a wide range of cardiovascular, neurologic, and renal complications in patients undergoing angiography. Full results are expected in the latter half of 2014 (ClinicalTrials.Gov # NCT00842868.

  7. Diabetes treatment patterns and goal achievement in primary diabetes care (DiaRegis) - study protocol and patient characteristics at baseline

    OpenAIRE

    Deeg Evelin; Plate Tanja; Krekler Michael; Gitt Anselm K; Binz Christiane; Bramlage Peter; Tschöpe Diethelm

    2010-01-01

    Abstract Background Patients with type 2 diabetes are at an increased risk for disease and treatment related complications after the initial approach of oral mono/dual antidiabetic therapy has failed. Data from clinical practice with respect to this patient group are however scarce. Therefore we set up a registry in primary care documenting the course and outcomes of this patient group. Methods Diabetes Treatment Patterns and Goal Achievement in Primary Diabetes Care (DiaRegis) is a prospecti...

  8. Design and baseline characteristics of participants in a phase III randomized trial of celecoxib and selenium for colorectal adenoma prevention

    OpenAIRE

    Thompson, Patricia; Roe, Denise J.; Fales, Liane; Buckmeier, Julie; Wang, Fang; Hamilton, Stanley R.; Bhattacharyya, Achyut; Green, Sylvan; Hsu, Chiu-Hsieh; Chow, H-H Sherry; Ahnen, Dennis J.; Boland, C Richard; Russell I. Heigh; Fay, David E.; Martinez, Maria Elena

    2012-01-01

    Cyclooxygenase (COX) inhibitors reduce colorectal adenoma recurrence by up to 45% and selenium supplementation may prevent colorectal cancer. Following colonoscopic adenoma resection, 1,600 men and women aged 40-80 years were randomized to celecoxib (400 mg daily), a selective COX-2 inhibitor, and/or selenium (200 μg daily as selenized yeast), or double placebo. The trial was initiated in November, 2001. The primary trial endpoint is adenoma recurrence in each intervention group compared to p...

  9. The Impact of Baseline Trend Control on Visual Analysis of Single-Case Data

    Science.gov (United States)

    Mercer, Sterett H.; Sterling, Heather E.

    2012-01-01

    The impact of baseline trend control on visual analyses of AB intervention graphs was examined with simulated data at various values of baseline trend, autocorrelation, and effect size. Participants included 202 undergraduate students with minimal training in visual analysis and 10 graduate students and faculty with more training and experience in…

  10. System maintenance test plan for the TWRS controlled baseline database system

    International Nuclear Information System (INIS)

    TWRS [Tank Waste Remediation System] Controlled Baseline Database, formally known as the Performance Measurement Control System, is used to track and monitor TWRS project management baseline information. This document contains the maintenance testing approach for software testing of the TCBD system once SCR/PRs are implemented

  11. EML Chester - 1982. Annual report of the Regional Baseline Station at Chester, New Jersey

    International Nuclear Information System (INIS)

    The Environmental Measurements Laboratory (EML) has maintained a regional baseline station at Chester, New Jersey since 1976. The site provides EML with a remote, rural facility for carrying out regional baseline research and for testing field equipment. This report updates the various programs underway at the Chester site. Separate abstracts have been prepared for the included papers

  12. Baseline study of radiology services for the purpose of PACS evaluation

    International Nuclear Information System (INIS)

    This paper reports initial results of a radiology department baseline study of workload and data flow patterns for image generation, film library activities, report generation reporting activities at the film alternators and report transcription and validation. The authors analyze the film based operations prior to full implementation of the image management and communication system. The baseline study topics are examined

  13. Suppression of baseline artifacts in 1H NMR spectroscopy of diluted water solutions

    International Nuclear Information System (INIS)

    Suppression of baseline artifacts in 1H NMR spectroscopy of diluted aqueous solutions has been discussed. The time-domain technique capable of eliminating or lowering the baseline distortions in the spectra caused by the ringing of low pas filters has been proposed. Simultaneously, the problem of proper adjusting of the start of data acquisition have been discussed

  14. Consideration of the baseline environment in examples of voluntary SEAs from Scotland

    International Nuclear Information System (INIS)

    Evidence from analysing and evaluating examples of three voluntary SEAs prepared in Scotland in the mid-late 1990s showed that different spatial and temporal scales were used when providing a baseline environment description. The SEAs analysed were prepared for: a wind farm siting programme that looked at national and short-term impacts; a land use plan that looked at regional and short-term impacts; and a transport plan that examined local and medium-term impacts. It was found that the two SEAs prepared by local government only considered impacts on the baseline environment within their jurisdictional boundaries whilst the SEA prepared by the private business considered impacts on the national baseline. A mixture of baseline data about planning, economic, environmental and social issues were included in the SEAs, however, evidence suggested that each SEA only focussed on those baseline features that might be significantly affected by the proposal. Each SEA also made extensive use of existing baseline information available from a variety of sources including local, and central government records and information from statutory bodies. All of the SEAs acknowledged that baseline data deficiencies existed and in certain cases steps were taken to obtain primary field data to help address these, however, it was also acknowledged that resource restrictions and decision-making deadlines limited the amount of primary baseline data that could be collected

  15. 76 FR 46283 - Peoples Natural Gas Company LLC; Notice of Baseline Filing

    Science.gov (United States)

    2011-08-02

    ... Energy Regulatory Commission Peoples Natural Gas Company LLC; Notice of Baseline Filing Take notice that on July 20, 2011, Peoples Natural Gas Company LLC submitted a revised baseline filing of their Statement of Operating Conditions for services provided under Section 311 of the Natural Gas Policy Act...

  16. 75 FR 37786 - DCP Guadalupe Pipeline, LLC; Notice of Baseline Filing

    Science.gov (United States)

    2010-06-30

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission DCP Guadalupe Pipeline, LLC; Notice of Baseline Filing June 23, 2010. Take notice that on June 10, 2010, DCP Guadalupe Pipeline, LLC submitted a baseline filing of its Storage Statement of Operating Conditions...

  17. 76 FR 7552 - DCP Guadalupe Pipeline, LLC; Notice of Baseline Filing

    Science.gov (United States)

    2011-02-10

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission DCP Guadalupe Pipeline, LLC; Notice of Baseline Filing Take notice that on February 3, 2011, DCP Guadalupe Pipeline, LLC submitted a revised baseline filing of their Statement of Operating Conditions for...

  18. 75 FR 38802 - DCP Raptor Pipeline, LLC; Notice of Baseline Filing

    Science.gov (United States)

    2010-07-06

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission DCP Raptor Pipeline, LLC; Notice of Baseline Filing June 28, 2010. Take notice that on June 22, 2010, DCP Raptor Pipeline, LLC submitted a baseline filing of its Statement of Operating Conditions for services...

  19. PERFORMANCE CALCULATION OF WAVELET TRANSFORMS FOR REMOVAL OF BASELINE WANDER FROM ECG

    Directory of Open Access Journals (Sweden)

    AMIT KUMAR MANOCHA

    2012-05-01

    Full Text Available As change in ST segment is an indication of ischemia in ECG and usually baseline wanders which are low frequency component of 0.5 to 1 Hz signal overlaps the ST segment in ECG, when the ECG is recorded by the electrodes from the chest of the patient. So Baseline wanders may makes wrong interpretation for the detection of ischemia and removal of baseline wander may cause another loss of important clinical information. This paper is to present the wavelet transform for estimation of baseline wanders in ECG and to find the effectiveness of this method by the Percent Root Mean Square Difference (PRD. Obtained results show that the wavelet transform approach performs successfully removal of baseline wanders. To test the proposed method, ECG signals obtained from European ST-T database have been used.

  20. High baseline activity in inferior temporal cortex improves neural and behavioral discriminability during visual categorization

    Directory of Open Access Journals (Sweden)

    Nazli eEmadi

    2014-11-01

    Full Text Available Spontaneous firing is a ubiquitous property of neural activity in the brain. Recent literature suggests that this baseline activity plays a key role in perception. However, it is not known how the baseline activity contributes to neural coding and behavior. Here, by recording from the single neurons in the inferior temporal cortex of monkeys performing a visual categorization task, we thoroughly explored the relationship between baseline activity, the evoked response, and behavior. Specifically we found that a low-frequency (< 8 Hz oscillation in the spike train, prior and phase-locked to the stimulus onset, was correlated with increased gamma power and neuronal baseline activity. This enhancement of the baseline activity was then followed by an increase in the neural selectivity and the response reliability and eventually a higher behavioral performance.