A mathematical model of symmetry based on mathematical definition
Institute of Scientific and Technical Information of China (English)
无
2002-01-01
Tolerance is imperative for seamless integration of CAD/CAM(Computer Aided Disign/Computer Aided Manufacture) which is just a text attribute and has no semantics in present CAD systems. There are many tolerance types, the relations between which are very complicated. In addition, the different principles of tolerance make study of tolerance difficult; and there may be various meanings or interpretation for the same type of tolerance because of the literal definition. In this work, latest unambiguous mathematical definition was applied to study, explain and clarify: (1) the formation and representation of tolerance zone, and (2) the formation and representation of variational elements; after which, the mathematical models of symmetry of different tolerance principles and different interpretations were derived. An example is given to illustrate the application of these models in tolerance analysis.
A mathematical model of symmetry based on mathematical definition
Institute of Scientific and Technical Information of China (English)
刘玉生; 杨将新; 吴昭同; 高曙明
2002-01-01
Tolerance is imperative for seamless integration of CAD/CAM(Computer Aided Disignd/Computer Aided Manufacture) which is just a text attribute and has no semantics in present CAD systems. There are many tolerance types, the relations between which are very complicated. In addition, the different principles of tolerance make study of tolerance difficult; and there may be various meanings or interpretation for the same type of tolerance beeanse of the literal definition. In this work, latest unambiguous mathematical definition was applied to study, explain and clarify: ( 1 ) the formation and representation of tolerance zone, and (2) the formation and representation of variational elements ; after which, the mathematical models of syrmmetry of different tolerance principles and different interpretations were derived. An example is given to illustrate the application of these models in tolerance analysis.
A New Activity-Based Cost (ABC) Mathematical Model
Institute of Scientific and Technical Information of China (English)
JIANG Shuo; SONG Lei
2003-01-01
Along with the product price competition growing intensely, it is apparently important for reasonably distributing and counting cost. But, in sharing indirect cost, traditional cost accounting unveils the limitations increasingly, especially in authenticity of cost information. And the accounting theory circles and industry circles begin seeking one kind of new accurate cost calculation method, and the activity-based cost (ABC) method emerges as the times require. In this paper, we will build its mathematical model by the basic principle of ABC, and will improve its mathematical model further. We will establish its comparison mathematical model and make the ABC method go a step further to its practical application.
DEFF Research Database (Denmark)
Blomhøj, Morten
2004-01-01
Developing competences for setting up, analysing and criticising mathematical models are normally seen as relevant only from and above upper secondary level. The general belief among teachers is that modelling activities presuppose conceptual understanding of the mathematics involved. Mathematical...... modelling, however, can be seen as a practice of teaching that place the relation between real life and mathematics into the centre of teaching and learning mathematics, and this is relevant at all levels. Modelling activities may motivate the learning process and help the learner to establish cognitive...... roots for the construction of important mathematical concepts. In addition competences for setting up, analysing and criticising modelling processes and the possible use of models is a formative aim in this own right for mathematics teaching in general education. The paper presents a theoretical...
Mathematical Modeling of Column-Base Connections under Monotonic Loading
Directory of Open Access Journals (Sweden)
Gholamreza Abdollahzadeh
2014-12-01
Full Text Available Some considerable damage to steel structures during the Hyogo-ken Nanbu Earthquake occurred. Among them, many exposed-type column bases failed in several consistent patterns, such as brittle base plate fracture, excessive bolt elongation, unexpected early bolt failure, and inferior construction work, etc. The lessons from these phenomena led to the need for improved understanding of column base behavior. Joint behavior must be modeled when analyzing semi-rigid frames, which is associated with a mathematical model of the moment–rotation curve. The most accurate model uses continuous nonlinear functions. This article presents three areas of steel joint research: (1 analysis methods of semi-rigid joints; (2 prediction methods for the mechanical behavior of joints; (3 mathematical representations of the moment–rotation curve. In the current study, a new exponential model to depict the moment–rotation relationship of column base connection is proposed. The proposed nonlinear model represents an approach to the prediction of M–θ curves, taking into account the possible failure modes and the deformation characteristics of the connection elements. The new model has three physical parameters, along with two curve-fitted factors. These physical parameters are generated from dimensional details of the connection, as well as the material properties. The M–θ curves obtained by the model are compared with published connection tests and 3D FEM research. The proposed mathematical model adequately comes close to characterizing M–θ behavior through the full range of loading/rotations. As a result, modeling of column base connections using the proposed mathematical model can give crucial beforehand information, and overcome the disadvantages of time consuming workmanship and cost of experimental studies.
Semantic Web Based Efficient Search Using Ontology and Mathematical Model
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K.Palaniammal
2014-01-01
Full Text Available The semantic web is the forthcoming technology in the world of search engine. It becomes mainly focused towards the search which is more meaningful rather than the syntactic search prevailing now. This proposed work concerns about the semantic search with respect to the educational domain. In this paper, we propose semantic web based efficient search using ontology and mathematical model that takes into account the misleading, unmatched kind of service information, lack of relevant domain knowledge and the wrong service queries. To solve these issues in this framework is designed to make three major contributions, which are ontology knowledge base, Natural Language Processing (NLP techniques and search model. Ontology knowledge base is to store domain specific service ontologies and service description entity (SDE metadata. The search model is to retrieve SDE metadata as efficient for Education lenders, which include mathematical model. The Natural language processing techniques for spell-check and synonym based search. The results are retrieved and stored in an ontology, which in terms prevents the data redundancy. The results are more accurate to search, sensitive to spell check and synonymous context. This paper reduces the user’s time and complexity in finding for the correct results of his/her search text and our model provides more accurate results. A series of experiments are conducted in order to respectively evaluate the mechanism and the employed mathematical model.
2016-01-01
This book provides a thorough introduction to the challenge of applying mathematics in real-world scenarios. Modelling tasks rarely involve well-defined categories, and they often require multidisciplinary input from mathematics, physics, computer sciences, or engineering. In keeping with this spirit of modelling, the book includes a wealth of cross-references between the chapters and frequently points to the real-world context. The book combines classical approaches to modelling with novel areas such as soft computing methods, inverse problems, and model uncertainty. Attention is also paid to the interaction between models, data and the use of mathematical software. The reader will find a broad selection of theoretical tools for practicing industrial mathematics, including the analysis of continuum models, probabilistic and discrete phenomena, and asymptotic and sensitivity analysis.
Information system based on the mathematical model of the EPS
Kalimoldayev, Maksat N.; Abdildayeva, Assel A.; Mamyrbayev, Orken Zh.; Akhmetzhanov, Maksat
2016-11-01
This article discusses the structure of an information system, the mathematical and information models of electric power systems. Currently, the major application areas include system relaying data communication systems and automation, automated dispatching and technological management of electric power facilities, as well as computer-aided calculation of energy resources. Automatic control of excitation (ARV) synchronous machines is one of the most effective ways to ensure the stability of power systems. However, the variety of possible options and modes even in a single grid pose significant obstacles to the development of the best means of ensuring sustainability. Thus, the use of ARVs to ensure stability in some cases may not be sufficient. Therefore, there is a need to develop an information system based on a mathematical model.
Mathematical model for light scanning system based on circular laser
Institute of Scientific and Technical Information of China (English)
Peiquan Xu; Shun Yao; Fenggui Lu; Xinhua Tang; Wei Zhang
2005-01-01
A novel light scanning system based on circular laser trajectory for welding robot is developed. With the help of image processing technique, intelligent laser welding could be realized. According to laser triangulation algorithm and Scheimpflug condition, mathematical model for circular laser vision is built.This scanning system projects circular laser onto welded seams and recovers the depth of the welded seams,escapes from shortcomings of less information, explains ambiguity and single tracking direction inherent in "spot" or "line" type laser trajectory. Three-dimensional (3D) model for welded seams could be recognized after depth recovery. The imaging error is investigated also.
Mathematical Modeling and Pure Mathematics
Usiskin, Zalman
2015-01-01
Common situations, like planning air travel, can become grist for mathematical modeling and can promote the mathematical ideas of variables, formulas, algebraic expressions, functions, and statistics. The purpose of this article is to illustrate how the mathematical modeling that is present in everyday situations can be naturally embedded in…
PREFACE: Physics-Based Mathematical Models for Nanotechnology
Voon, Lok C. Lew Yan; Melnik, Roderick; Willatzen, Morten
2008-03-01
stain-resistant clothing, but with thousands more anticipated. The focus of this interdisciplinary workshop was on determining what kind of new theoretical and computational tools will be needed to advance the science and engineering of nanomaterials and nanostructures. Thanks to the stimulating environment of the BIRS, participants of the workshop had plenty of opportunity to exchange new ideas on one of the main topics of this workshop—physics-based mathematical models for the description of low-dimensional semiconductor nanostructures (LDSNs) that are becoming increasingly important in technological innovations. The main objective of the workshop was to bring together some of the world leading experts in the field from each of the key research communities working on different aspects of LDSNs in order to (a) summarize the state-of-the-art models and computational techniques for modeling LDSNs, (b) identify critical problems of major importance that require solution and prioritize them, (c) analyze feasibility of existing mathematical and computational methodologies for the solution of some such problems, and (d) use some of the workshop working sessions to explore promising approaches in addressing identified challenges. With the possibility of growing practically any shape and size of heterostructures, it becomes essential to understand the mathematical properties of quantum-confined structures including properties of bulk states, interface states, and surface states as a function of shape, size, and internal strain. This workshop put strong emphasis on discussions of the new mathematics needed in nanotechnology especially in relation to geometry and material-combination optimization of device properties such as electronic, optical, and magnetic properties. The problems that were addressed at this meeting are of immense importance in determining such quantum-mechanical properties and the group of invited participants covered very well all the relevant disciplines
Teaching Mathematical Modelling.
Jones, Mark S.
1997-01-01
Outlines a course at the University of Glamorgan in the United Kingdom in which a computer algebra system (CAS) teaches mathematical modeling. The format is based on continual assessment of group and individual work stating the problem, a feature list, and formulation of the models. No additional mathematical word processing package is necessary.…
Mathematical Modeling of Carcinogenesis Based on Chromosome Aberration Data
Institute of Scientific and Technical Information of China (English)
Xiao-bo Li
2009-01-01
Objective: The progression of human cancer is characterized by the accumulation of genetic instability. An increasing number of experimental genetic molecular techniques have been used to detect chromosome aberrations. Previous studies on chromosome abnormalities often focused on identifying the frequent loci of chromosome alterations, but rarely addressed the issue of interrelationship of chromosomal abnormalities. In the last few years, several mathematical models have been employed to construct models of carcinogenesis, in an attempt to identify the time order and cause-and-effect relationship of chromosome aberrations. The principles and applications of these models are reviewed and compared in this paper. Mathematical modeling of carcinogenesis can contribute to our understanding of the molecular genetics of tumor development, and identification of cancer related genes, thus leading to improved clinical practice of cancer.
Mathematical model of delay lines based on magnetostatic waves
Directory of Open Access Journals (Sweden)
E. V. Kudinov
2010-12-01
Full Text Available On the example of the delay line have demonstrated the possibility of applying the principle of decomposition to construct mathematical models of microwave devices using magnetostatic waves (MSW in a magnetized epitaxial ferrite films, which allows for a unified methodological basis and the lowest cost to the experimental optimization design of MSW devices for various applications
Finite mathematics models and applications
Morris, Carla C
2015-01-01
Features step-by-step examples based on actual data and connects fundamental mathematical modeling skills and decision making concepts to everyday applicability Featuring key linear programming, matrix, and probability concepts, Finite Mathematics: Models and Applications emphasizes cross-disciplinary applications that relate mathematics to everyday life. The book provides a unique combination of practical mathematical applications to illustrate the wide use of mathematics in fields ranging from business, economics, finance, management, operations research, and the life and social sciences.
Wright, Vince
2014-01-01
Pirie and Kieren (1989 "For the learning of mathematics", 9(3)7-11, 1992 "Journal of Mathematical Behavior", 11, 243-257, 1994a "Educational Studies in Mathematics", 26, 61-86, 1994b "For the Learning of Mathematics":, 14(1)39-43) created a model (P-K) that describes a dynamic and recursive process by which…
Directory of Open Access Journals (Sweden)
Edwin Musdi
2016-02-01
Full Text Available This research aims to develop a mathematics instructional model based realistic mathematics education (RME to promote students' problem-solving abilities. The design research used Plomp models, which consists of preliminary phase, development or proto-typing phase and assessment phase. At this study, only the first two phases conducted. The first phase, a preliminary investigation, carried out with a literature study to examine the theory-based instructional learning RME model, characteristics of learners, learning management descriptions by junior high school mathematics teacher and relevant research. The development phase is done by developing a draft model (an early prototype model that consists of the syntax, the social system, the principle of reaction, support systems, and the impact and effects of instructional support. Early prototype model contain a draft model, lesson plans, worksheets, and assessments. Tesssmer formative evaluation model used to revise the model. In this study only phase of one to one evaluation conducted. In the ppreliminary phase has produced a theory-based learning RME model, a description of the characteristics of learners in grade VIII Junior High School Padang and the description of teacher teaching in the classroom. The result showed that most students were still not be able to solve the non-routine problem. Teachers did not optimally facilitate students to develop problem-solving skills of students. It was recommended that the model can be applied in the classroom.
Directory of Open Access Journals (Sweden)
Tudor Barbu
2014-06-01
Full Text Available A nonlinear diffusion based image denoising technique is introduced in this paper. The proposed PDE denoising and restoration scheme is based on a novel diffusivity function that uses an automatically detected conductance parameter. A robust mathematical treatment is also provided for our anisotropic diffusion model. We demonstrate that edge-stopping function model is properly chosen, explaining the mathematical reasons behind it. Also, we perform a rigorous mathematical investigation on of the existence and uniqueness of the solution of our nonlinear diffusion equation. This PDE-based noise removal approach outperforms most diffusion-based methods, producing considerably better smoothing results and providing a much better edge preservation.
Mathematical models of morphogenesis
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Dilão Rui
2015-01-01
Full Text Available Morphogenesis is the ensemble of phenomena that generates the form and shape of organisms. Organisms are classified according to some of its structural characteristics, to its metabolism and to its form. In particular, the empirical classification associated with the phylum concept is related with the form and shape of organisms. In the first part of this talk, we introduce the class of mathematical models associated the Turing approach to pattern formation. In the Turing approach, morphogenesis models are described by reaction-diffusion parabolic partial differential equations. Based on this formalism, we present a mathematical model describing the first two hours of development of the fruit fly Drosophila. In the second part of this talk, we present results on Pareto optimality to calibrate and validate mathematical models.
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
On the basis of analysis on the temperature monitoring methods for high voltage devices, a new type of fiber optic sensor structure with reference channel is given. And the operation principle of fiber optic sensor is analysed at large based on the absorption of semiconductor chip. The mathematical model of both devices and the whole system are also given. It is proved by the experiment that this mathematical model is reliable.
Teaching Mathematical Modeling in Mathematics Education
Saxena, Ritu; Shrivastava, Keerty; Bhardwaj, Ramakant
2016-01-01
Mathematics is not only a subject but it is also a language consisting of many different symbols and relations. Taught as a compulsory subject up the 10th class, students are then able to choose whether or not to study mathematics as a main subject. The present paper discusses mathematical modeling in mathematics education. The article provides…
Mathematical Modelling of a Hybrid Micro-Cogeneration Group Based on a Four Stroke Diesel Engine
Directory of Open Access Journals (Sweden)
Apostol Valentin
2014-06-01
Full Text Available The paper presents a part of the work conducted in the first stage of a Research Grant called ”Hybrid micro-cogeneration group of high efficiency equipped with an electronically assisted ORC” acronym GRUCOHYB. The hybrid micro-cogeneration group is equipped with a four stroke Diesel engine having a maximum power of 40 kW. A mathematical model of the internal combustion engine is presented. The mathematical model is developed based on the Laws of Thermodynamics and takes into account the real, irreversible processes. Based on the mathematical model a computation program was developed. The results obtained were compared with those provided by the Diesel engine manufacturer. Results show a very high correlation between the manufacturer’s data and the simulation results for an engine running at 100% load. Future developments could involve using an exergetic analysis to show the ability of the ORC to generate electricity from recovered heat
Modelers' perception of mathematical modeling in epidemiology: a web-based survey.
Directory of Open Access Journals (Sweden)
Gilles Hejblum
Full Text Available BACKGROUND: Mathematical modeling in epidemiology (MME is being used increasingly. However, there are many uncertainties in terms of definitions, uses and quality features of MME. METHODOLOGY/PRINCIPAL FINDINGS: To delineate the current status of these models, a 10-item questionnaire on MME was devised. Proposed via an anonymous internet-based survey, the questionnaire was completed by 189 scientists who had published in the domain of MME. A small minority (18% of respondents claimed to have in mind a concise definition of MME. Some techniques were identified by the researchers as characterizing MME (e.g. Markov models, while others-at the same level of sophistication in terms of mathematics-were not (e.g. Cox regression. The researchers' opinions were also contrasted about the potential applications of MME, perceived as highly relevant for providing insight into complex mechanisms and less relevant for identifying causal factors. The quality criteria were those of good science and were not related to the size and the nature of the public health problems addressed. CONCLUSIONS/SIGNIFICANCE: This study shows that perceptions on the nature, uses and quality criteria of MME are contrasted, even among the very community of published authors in this domain. Nevertheless, MME is an emerging discipline in epidemiology and this study underlines that it is associated with specific areas of application and methods. The development of this discipline is likely to deserve a framework providing recommendations and guidance at various steps of the studies, from design to report.
Petersen, Richard H.
1997-01-01
The objectives of the Institute were: (a) increase participants' content knowledge about aeronautics, science, mathematics, and technology, (b) model and promote the use of scientific inquiry through problem-based learning, (c) investigate the use of instructional technologies and their applications to curricula, and (d) encourage the dissemination of TEI experiences to colleagues, students, and parents.
Directory of Open Access Journals (Sweden)
Dinh An Nguyen
2012-07-01
Full Text Available Many of the Proton Exchange Membrane Fuel Cell (PEMFC models proposed in the literature consist of mathematical equations. However, they are not adequately practical for simulating power systems. The proposed model takes into account phenomena such as activation polarization, ohmic polarization, double layer capacitance and mass transport effects present in a PEM fuel cell. Using electrical analogies and a mathematical modeling of PEMFC, the circuit model is established. To evaluate the effectiveness of the circuit model, its static and dynamic performances under load step changes are simulated and compared to the numerical results obtained by solving the mathematical model. Finally, the applicability of our model is demonstrated by simulating a practical system.
Wright, Vince
2014-03-01
Pirie and Kieren (1989 For the learning of mathematics, 9(3)7-11, 1992 Journal of Mathematical Behavior, 11, 243-257, 1994a Educational Studies in Mathematics, 26, 61-86, 1994b For the Learning of Mathematics, 14(1)39-43) created a model (P-K) that describes a dynamic and recursive process by which learners develop their mathematical understanding. The model was adapted to create the teaching model used in the New Zealand Numeracy Development Projects (Ministry of Education, 2007). A case study of a 3-week sequence of instruction with a group of eight 12- and 13-year-old students provided the data. The teacher/researcher used folding back to materials and images and progressing from materials to imaging to number properties to assist students to develop their understanding of frequencies as proportions. The data show that successful implementation of the model is dependent on the teacher noticing and responding to the layers of understanding demonstrated by the students and the careful selection of materials, problems and situations. It supports the use of the model as a useful part of teachers' instructional strategies and the importance of pedagogical content knowledge to the quality of the way the model is used.
Mathematical Model of Natural Gas Desulfurization Based on Membrane Absorption
Institute of Scientific and Technical Information of China (English)
Wang Shuli; Ma Jun; Wang Ganyu; Zhou Heng
2014-01-01
Models of mass transfer kinetics combined with mass transfer differential equation and mass transfer resistance equation were established on the basis of double-iflm theory. Mass transfer process of H2S absorption by means of polypro-pylene hydrophobic microporous hollow ifber membrane contactor was simulated using MDEA (N-methyldiethanolamine) as the absorption liquid and corresponding experiments of natural gas desulfurization were performed. The simulation re-sults indicated that the removal rate of hydrogen sulifde showed positive dependence on the absorption liquid concentration and gas pressure. However, the desulfurization rate showed negative dependence on gas lfow. The simulated values were in good agreement with the experimental results. The in-tube concentration of hydrogen sulifde at the same point increased with increase in the gas velocity. Axial concentration of hydrogen sulifde decreased rapidly at the beginning, and the de-crease saw a slowdown during the latter half period. Hydrogen sulifde concentration dropped quickly in the radial direction, and the reduction in the radial direction was weakened with the increase of axial length due to the gradual reduction of hy-drogen sulifde concentration along the tube. The desulfurization rate under given operating conditions can be predicted by this model, and the theoretical basis for membrane module design can also be provided.
Developing mathematical modelling competence
DEFF Research Database (Denmark)
Blomhøj, Morten; Jensen, Tomas Højgaard
2003-01-01
In this paper we introduce the concept of mathematical modelling competence, by which we mean being able to carry through a whole mathematical modelling process in a certain context. Analysing the structure of this process, six sub-competences are identified. Mathematical modelling competence...... cannot be reduced to these six sub-competences, but they are necessary elements in the development of mathematical modelling competence. Experience from the development of a modelling course is used to illustrate how the different nature of the sub-competences can be used as a tool for finding...... the balance between different kinds of activities in a particular educational setting. Obstacles of social, cognitive and affective nature for the students' development of mathematical modelling competence are reported and discussed in relation to the sub-competences....
Yilmaz, Suha; Tekin-Dede, Ayse
2016-01-01
Mathematization competency is considered in the field as the focus of modelling process. Considering the various definitions, the components of the mathematization competency are determined as identifying assumptions, identifying variables based on the assumptions and constructing mathematical model/s based on the relations among identified…
Mathematical modelling techniques
Aris, Rutherford
1995-01-01
""Engaging, elegantly written."" - Applied Mathematical ModellingMathematical modelling is a highly useful methodology designed to enable mathematicians, physicists and other scientists to formulate equations from a given nonmathematical situation. In this elegantly written volume, a distinguished theoretical chemist and engineer sets down helpful rules not only for setting up models but also for solving the mathematical problems they pose and for evaluating models.The author begins with a discussion of the term ""model,"" followed by clearly presented examples of the different types of mode
An introduction to mathematical modeling
Bender, Edward A
2000-01-01
Employing a practical, ""learn by doing"" approach, this first-rate text fosters the development of the skills beyond the pure mathematics needed to set up and manipulate mathematical models. The author draws on a diversity of fields - including science, engineering, and operations research - to provide over 100 reality-based examples. Students learn from the examples by applying mathematical methods to formulate, analyze, and criticize models. Extensive documentation, consisting of over 150 references, supplements the models, encouraging further research on models of particular interest. The
Institute of Scientific and Technical Information of China (English)
SHU Linsen; CAO Huajun; LI Xianchong; ZHANG Chenglong; LI Yuxia
2015-01-01
The current researches on the tooth surface mathematical equations and the theory of gearing malnly pay attention to the ordinary type worm gear set (e.g., ZN, ZA, or ZK). The research of forming mechanism and three-dimensional modeling method for the double pitch worm gear set is not enough. So there are some difficulties in mathematical model deducing and geometry modeling of double pitch ZN-type worm gear set based on generation mechanism. In order to establish the mathematical model and the precise geometric model of double pitch ZN-type worm gear set, the structural characteristics and generation mechanism of the double pitch ZN-type worm gear set are investigated. Mathematical model of the ZN-type worm gear set is derived based on its generation mechanism and the theory of gearing. According to the mathematical model of the worm gear set which has been developed, a geometry modeling method of the double pitch ZN-type worm and worm gear is presented. Furthermore, a geometrical precision calculate method is proposed to evaluate the geometrical quality of the double pitch worm gear set. As a result, the maximum error is less than 6´10–4 mm in magnitude, thus the model of the double pitch ZN-type worm gear set is avallable to meet the requirements of finite element analysis and engineering application. The derived mathematical model and the proposed geometrical modeling method are helpful to guiding the design, manufacture and contact analysis of the worm gear set.
Applied impulsive mathematical models
Stamova, Ivanka
2016-01-01
Using the theory of impulsive differential equations, this book focuses on mathematical models which reflect current research in biology, population dynamics, neural networks and economics. The authors provide the basic background from the fundamental theory and give a systematic exposition of recent results related to the qualitative analysis of impulsive mathematical models. Consisting of six chapters, the book presents many applicable techniques, making them available in a single source easily accessible to researchers interested in mathematical models and their applications. Serving as a valuable reference, this text is addressed to a wide audience of professionals, including mathematicians, applied researchers and practitioners.
DEFF Research Database (Denmark)
Carugati, Andrea
2002-01-01
has been initiated with the scope of investigating the questions that mathematical modelling technology poses to traditional information systems development projects. Based on the past body of research, this study proposes a framework to guide decision making for managing projects of information......’ skills in the development process. Further observations also indicate that flexibility and adaptability, based on grounded theory, are valuable tools when information systems development involves a new technology.......The advancements in complexity and sophistication of mathematical models for manufacturing scheduling and control and the increase of the ratio power/cost of computers are beginning to provide the manufacturing industry with new software tools to improve production. A Danish action research project...
Applying Mathematical Optimization Methods to an ACT-R Instance-Based Learning Model.
Directory of Open Access Journals (Sweden)
Nadia Said
Full Text Available Computational models of cognition provide an interface to connect advanced mathematical tools and methods to empirically supported theories of behavior in psychology, cognitive science, and neuroscience. In this article, we consider a computational model of instance-based learning, implemented in the ACT-R cognitive architecture. We propose an approach for obtaining mathematical reformulations of such cognitive models that improve their computational tractability. For the well-established Sugar Factory dynamic decision making task, we conduct a simulation study to analyze central model parameters. We show how mathematical optimization techniques can be applied to efficiently identify optimal parameter values with respect to different optimization goals. Beyond these methodological contributions, our analysis reveals the sensitivity of this particular task with respect to initial settings and yields new insights into how average human performance deviates from potential optimal performance. We conclude by discussing possible extensions of our approach as well as future steps towards applying more powerful derivative-based optimization methods.
Phase errors elimination in compact digital holoscope (CDH) based on a reasonable mathematical model
Wen, Yongfu; Qu, Weijuan; Cheng, Cheeyuen; Wang, Zhaomin; Asundi, Anand
2015-03-01
In the compact digital holoscope (CDH) measurement process, theoretically, we need to ensure the distances between the reference wave and object wave to the hologram plane exactly match. However, it is not easy to realize in practice due to the human factors. This can lead to a phase error in the reconstruction result. In this paper, the strict theoretical analysis of the wavefront interference is performed to demonstrate the mathematical model of the phase error and then a phase errors elimination method is proposed based on the advanced mathematical model, which has a more explicit physical meaning. Experiments are carried out to verify the performance of the presented method and the results indicate that it is effective and allows the operator can make operation more flexible.
Institute of Scientific and Technical Information of China (English)
JIA Jin-zhang
2008-01-01
The occurrence of local circulating ventilation can be caused by many factors,such as the airflow reversion during mine fire, the improper arrangement of local fan or underground fan station and the man-made error input of raw data before network solving.Once circulating ventilations occur, the corresponding branches in the ventilation network corresponding to the relevant airways in ventilation system form circuits, and all the directions of the branches in the circuits are identical, which is the unidirectional problem in ventilation network. Based on the properties of node adjacent matrix, a serial of mathematical computation to node adjacent matrix were performed, and a mathematical model for determining unidirectional circuits based on node adjacent matrix was put forward.
MATHEMATICAL MODEL OF OPTIMAL PROJECT PORTFOLIO FORMING BASED ON RANDOM FACTORS
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I. A. Korkhina
2014-03-01
Full Text Available Purpose. To identify the ways of perspective development for railway transport one should solve the problem of forming the investment project portfolio. Thus, it is necessary to deal with uncertainty in the input data (prices of services, materials, energy products. To take into account this uncertainty it is proposed to use the developed model of stochastic programming. Methodology. For accounting of uncertain data the probabilistic limits on the quantities of resources, which are used in the project portfolio are imposed. As the objective function it is proposed to maximize the threshold, which with a given probability may exceed the planning interval of the net income. Findings. Stochastic programming model with line-by-line probabilistic constraints was obtained. Coefficients of this model are normally distributed random variables. Ratios, which allow calculating mathematical expectations and covariance matrices of these coefficients, were concluded. Originality. Known methods of forming the optimal project portfolio are based on the fact that all inputs are known exactly. On the basis of this consideration, the authors of works on the creating an optimal project portfolio have come to a scheme of deterministic mathematical programming. In this article we propose to take into account the uncertainty in the input data, which will increase the reliability of the portfolio effectiveness estimation through the use of stochastic mathematical programming scheme. Practical value. The developed model can be used in order to solve the planning problems of railway transport development.
A biologically based mathematical model for the induction of liver tumors in mice by dichloroacetic acid (DCA) has been developed from histopathologic analysis of the livers of exposed mice. This analysis suggests that following chronic exposure to DCA, carcinomas can arise dire...
Representations used by mathematics student teachers in mathematical modeling process
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Aytuğ Özaltun
2014-02-01
Full Text Available The purpose of this study is to determine representations used by mathematics student teachers in steps of mathematical modeling process based on their solutions of problems formed in the context of different classification of modeling. The study was conducted with fifteen secondary mathematics student teachers given a Mathematical Modeling course. The participants were separated into five collaboration groups of three students. Data were collected with the detailed written papers given by the groups for the problems and GeoGebra solution files. The groups benefited from verbal, algebraic, figural, tabular and dynamic representations while they were solving the problems. Considering all steps of the process, groups at most used verbal and algebraic representations. While they used only verbal representation in analyzing the problem, they benefited from at most verbal representation and then figural representation in establishing the systematic structure. The most used is algebraic and then verbal representations in the steps of mathematization, meta-mathematization, and mathematical analysis. In the steps of interpretation/evaluation and the model verification, the groups mainly benefited from verbal and then algebraic representations. Further researches towards why representations are preferred in the specific steps of the mathematical modeling process are suggested.Key Words: Mathematical modeling, modeling problems, mathematics student teachers, representations.
Mathematical modelling of metabolism
DEFF Research Database (Denmark)
Gombert, Andreas Karoly; Nielsen, Jens
2000-01-01
Mathematical models of the cellular metabolism have a special interest within biotechnology. Many different kinds of commercially important products are derived from the cell factory, and metabolic engineering can be applied to improve existing production processes, as well as to make new processes...... availability of genomic information and powerful analytical techniques, mathematical models also serve as a tool for understanding the cellular metabolism and physiology....... available. Both stoichiometric and kinetic models have been used to investigate the metabolism, which has resulted in defining the optimal fermentation conditions, as well as in directing the genetic changes to be introduced in order to obtain a good producer strain or cell line. With the increasing...
Principles of mathematical modeling
Dym, Clive
2004-01-01
Science and engineering students depend heavily on concepts of mathematical modeling. In an age where almost everything is done on a computer, author Clive Dym believes that students need to understand and "own" the underlying mathematics that computers are doing on their behalf. His goal for Principles of Mathematical Modeling, Second Edition, is to engage the student reader in developing a foundational understanding of the subject that will serve them well into their careers. The first half of the book begins with a clearly defined set of modeling principles, and then introduces a set of foundational tools including dimensional analysis, scaling techniques, and approximation and validation techniques. The second half demonstrates the latest applications for these tools to a broad variety of subjects, including exponential growth and decay in fields ranging from biology to economics, traffic flow, free and forced vibration of mechanical and other systems, and optimization problems in biology, structures, an...
Concepts of mathematical modeling
Meyer, Walter J
2004-01-01
Appropriate for undergraduate and graduate students, this text features independent sections that illustrate the most important principles of mathematical modeling, a variety of applications, and classic models. Students with a solid background in calculus and some knowledge of probability and matrix theory will find the material entirely accessible. The range of subjects includes topics from the physical, biological, and social sciences, as well as those of operations research. Discussions cover related mathematical tools and the historical eras from which the applications are drawn. Each sec
Mathematical Modeling of Biosensors Based on an Array of Enzyme Microreactors
Directory of Open Access Journals (Sweden)
Juozas Kulys
2006-04-01
Full Text Available This paper presents a two-dimensional-in-space mathematical model ofbiosensors based on an array of enzyme microreactors immobilised on a single electrode.The modeling system acts under amperometric conditions. The microreactors were modeledby particles and by strips. The model is based on the diffusion equations containing a non-linear term related to the Michaelis-Menten kinetics of the enzymatic reaction. The modelinvolves three regions: an array of enzyme microreactors where enzyme reaction as well asmass transport by diffusion takes place, a diffusion limiting region where only the diffusiontakes place, and a convective region, where the analyte concentration is maintained constant.Using computer simulation, the influence of the geometry of the microreactors and of thediffusion region on the biosensor response was investigated. The digital simulation wascarried out using the finite difference technique.
Perspectives of IT Artefacts: Information Systems based on Complex Mathematical Models
DEFF Research Database (Denmark)
Carugati, Andrea
2002-01-01
A solution for production scheduling that is lately attracting the interests of the manufacturing industry involves the use of complex mathematical modeling techniques in scheduling software. However this technology is fairly unknown among manufacturing practitioners, as are the social problems...... of its development and use. The aim of this article is to show how an approach based on multiple perspectives can help understand the emergence of complex software and help understand why and how the reasons and motives of the different stakeholders are, at times, incompatible....
Parshin, D. V.; Ufimtseva, I. V.; Cherevko, A. A.; Khe, A. K.; Orlov, K. Yu; Krivoshapkin, A. L.; Chupakhin, A. P.
2016-06-01
The present paper discusses the method of identification (diseased/healthy) human cerebral vessels by using of mathematical model. Human cerebral circulation as a single tuned circuit, which consists of blood flow, elastic vessels and elastic brain gel tissue is under consideration. Non linear Van der Pol-Duffing equation is assumed as mathematical model of cerebrovascular circulation. Hypothesis of vascular pathology existence in some position of blood vessel, based on mathematical model properties for this position is formulated. Good reliability of hypothesis is proved statistically for 7 patients with arterial aneurysms.
Design and Simulation of Mathematical Models- An DSP and Digital Communication Based Approach
Directory of Open Access Journals (Sweden)
Miss. Shruti R. Tambakhe
2014-04-01
Full Text Available A methodology for implementing DSP based or communication applications on a field programmable gate arrays (FPGA using Xilinx System Generator (XSG for Matlab. The DPSK system and FFT are simulated using Matlab/ Simulink environment and System Generator, a tool from Xilinx used for FPGA design as well as implemented on Spartan 3E Starter Kit boards. We proposed the concept of simulation of mathematical model on mixed HDL-Simulink using Xilinx system generator. Many applications that are DSP based or certain communication application require mathematical modelling for their easy understanding and analysis. Due to its complexity Pure HDL is unable to simulate. Also it terms to be costly and time consuming process. The implementation of FFT algorithms that can compute fourier transform of varied signals in real time for frequency analysis of signals on FPGAs (Spartan3E. With large demand for high dynamic range for applications, floating point implementation is used as fixed point implementation becomes increasingly expensive. The DPSK model are first board behaves as a modulator and the second as a demodulator. The modulator and demodulator algorithms have been implemented on FPGA using the VHDL language on Xilinx ISE.
Marković, D Z; Kalauzi, A; Radenović, C N
2001-09-01
The paper deals with mathematical modelling of the transients obtained by fitting of delayed fluorescence (DF) induction trace. The transients are in certain, doubtless connection with electrochemical gradient (ECG) formed across thylakoid membranes upon illumination. The fitting of the C and D transients by using consecutive model for first-order reactions (A --> B --> C) showed that they might play a role of the intermediate (B), according to scheme down bellow: ("A1 state")ECG (k1(C transient))--> C transient (k2(C transient))--> products, ("A2 state")ECG (k1(D transient))--> D transient (k2(D transient))--> products. The two ECG controlled "states" (A1 & A2) are not the same, which does not exclude some sort of proportionality. On the other hand, the E band, contributing mainly to the stationary level of DF induction trace, may be fitted by parallel model of at least two first-order reactions.
A biophysically based mathematical model for the catalytic mechanism of glutathione reductase.
Pannala, Venkat R; Bazil, Jason N; Camara, Amadou K S; Dash, Ranjan K
2013-12-01
Glutathione reductase (GR) catalyzes the reduction of oxidized glutathione (GSSG) to reduced glutathione (GSH) using NADPH as the reducing cofactor, and thereby maintains a constant GSH level in the system. GSH scavenges superoxide (O2(*-)) and hydroxyl radicals (OH) nonenzymatically or by serving as an electron donor to several enzymes involved in reactive oxygen species (ROS) detoxification. In either case, GSH oxidizes to GSSG and is subsequently regenerated by the catalytic action of GR. Although the GR kinetic mechanism has been extensively studied under various experimental conditions with variable substrates and products, the catalytic mechanism has not been studied in terms of a mechanistic model that accounts for the effects of the substrates and products on the reaction kinetics. The aim of this study is therefore to develop a comprehensive mathematical model for the catalytic mechanism of GR. We use available experimental data on GR kinetics from various species/sources to develop the mathematical model and estimate the associated model parameters. The model simulations are consistent with the experimental observation that GR operates via both ping-pong and sequential branching mechanisms based on relevant concentrations of its reaction substrate GSSG. Furthermore, we show the observed pH-dependent substrate inhibition of GR activity by GSSG and bimodal behavior of GR activity with pH. The model presents a unique opportunity to understand the effects of products on the kinetics of GR. The model simulations show that under physiological conditions, where both substrates and products are present, the flux distribution depends on the concentrations of both GSSG and NADP(+), with ping-pong flux operating at low levels and sequential flux dominating at higher levels. The kinetic model of GR may serve as a key module for the development of integrated models for ROS-scavenging systems to understand protection of cells under normal and oxidative stress
Mathematical models of hysteresis
Energy Technology Data Exchange (ETDEWEB)
NONE
1998-08-01
The ongoing research has largely been focused on the development of mathematical models of hysteretic nonlinearities with nonlocal memories. The distinct feature of these nonlinearities is that their current states depend on past histories of input variations. It turns out that memories of hysteretic nonlinearities are quite selective. Indeed, experiments show that only some past input extrema (not the entire input variations) leave their marks upon future states of hysteretic nonlinearities. Thus special mathematical tools are needed in order to describe nonlocal selective memories of hysteretic nonlinearities. The origin of such tools can be traced back to the landmark paper of Preisach. Their research has been primarily concerned with Preisach-type models of hysteresis. All these models have a common generic feature; they are constructed as superpositions of simplest hysteretic nonlinearities-rectangular loops. During the past four years, the study has been by and large centered around the following topics: (1) further development of Scalar and vector Preisach-type models of hysteresis; (2) experimental testing of Preisach-type models of hysteresis; (3) development of new models for viscosity (aftereffect) in hysteretic systems; (4) development of mathematical models for superconducting hysteresis in the case of gradual resistive transitions; (5) software implementation of Preisach-type models of hysteresis; and (6) development of new ideas which have emerged in the course of the research work. The author briefly describes the main scientific results obtained in the areas outlined above.
Energy Technology Data Exchange (ETDEWEB)
Salloum, Maher N.; Gharagozloo, Patricia E.
2013-10-01
Metal particle beds have recently become a major technique for hydrogen storage. In order to extract hydrogen from such beds, it is crucial to understand the decomposition kinetics of the metal hydride. We are interested in obtaining a a better understanding of the uranium hydride (UH3) decomposition kinetics. We first developed an empirical model by fitting data compiled from different experimental studies in the literature and quantified the uncertainty resulting from the scattered data. We found that the decomposition time range predicted by the obtained kinetics was in a good agreement with published experimental results. Secondly, we developed a physics based mathematical model to simulate the rate of hydrogen diffusion in a hydride particle during the decomposition. We used this model to simulate the decomposition of the particles for temperatures ranging from 300K to 1000K while propagating parametric uncertainty and evaluated the kinetics from the results. We compared the kinetics parameters derived from the empirical and physics based models and found that the uncertainty in the kinetics predicted by the physics based model covers the scattered experimental data. Finally, we used the physics-based kinetics parameters to simulate the effects of boundary resistances and powder morphological changes during decomposition in a continuum level model. We found that the species change within the bed occurring during the decomposition accelerates the hydrogen flow by increasing the bed permeability, while the pressure buildup and the thermal barrier forming at the wall significantly impede the hydrogen extraction.
Mathematical modeling in psychological researches
Directory of Open Access Journals (Sweden)
Aleksandra Zyolko
2013-04-01
Full Text Available The author considers the nature of mathematical modeling and its significance in psychological researches. The author distinguishes the types of mathematical models: deterministic, stochastic models and synergetic models. The system approach is proposed as an instrument of implementation of mathematical modelling in psychological research.
A process-based mathematical model on methane production with emission indices for control.
Chakraborty, A; Bhattacharaya, D K
2006-08-01
In this paper, a process-based mathematical model is developed for the production of methane through biodegradation. It is a three-dimensional model given by ordinary differential equations. The results of the analysis of the model are interpreted through three emission indices, which are introduced for the first time. The estimation of either one or all of them can interpret the feasibility of the equilibrium and the long-term emission tendency of methane. The vulnerability of the methane production process with respect to soil temperature effects in methanogenic phase has been discussed and a feasible condition within a specified temperature range has defined for the nonvulnerability of the methane production process and also it has shown that under the same condition, zero-emission process of methane will be nonvulnerable with respect to the soil temperature effects in methanogenic phase. Lastly, condition for zero emission of methane is also obtained and it is interpreted through the emission indices.
Optimization of Cooling Process of Iron Ore Pellets Based on Mathematical Model and Data Mining
Institute of Scientific and Technical Information of China (English)
Gui-ming YANG; Xiao-hui FAN; Xu-ling CHEN; Xiao-xian HUANG; Xi LI
2015-01-01
Cooling process of iron ore pellets in a circular cooler has great impacts on the pellet quality and systematic energy exploitation. However, multi-variables and non-visualization of this gray system is unfavorable to efifcient production. Thus, the cooling process of iron ore pellets was optimized using mathematical model and data mining techniques. A mathematical model was established and validated by steady-state production data, and the results show that the calculated values coincide very well with the measured values. Based on the proposed model, effects of important process parameters on gas-pellet temperature proifles within the circular cooler were analyzed to better understand the entire cooling process. Two data mining techniques—Associa-tion Rules Induction and Clustering were also applied on the steady-state production data to obtain expertise operating rules and optimized targets. Finally, an optimized control strategy for the circular cooler was proposed and an operation guidance system was developed. The system could realize the visualization of thermal process at steady state and provide operation guidance to optimize the circular cooler.
Directory of Open Access Journals (Sweden)
Sayantan Nath
2015-09-01
Full Text Available In this paper, integration between multiple functions of image processing and its statistical parameters for intelligent alarming series based fire detection system is presented. The proper inter-connectivity mapping between processing elements of imagery based on classification factor for temperature monitoring and multilevel intelligent alarm sequence is introduced by abstractive canonical approach. The flow of image processing components between core implementation of intelligent alarming system with temperature wise area segmentation as well as boundary detection technique is not yet fully explored in the present era of thermal imaging. In the light of analytical perspective of convolutive functionalism in thermal imaging, the abstract algebra based inter-mapping model between event-calculus supported DAGSVM classification for step-by-step generation of alarm series with gradual monitoring technique and segmentation of regions with its affected boundaries in thermographic image of coal with respect to temperature distinctions is discussed. The connectedness of the multifunctional operations of image processing based compatible fire protection system with proper monitoring sequence is presently investigated here. The mathematical models representing the relation between the temperature affected areas and its boundary in the obtained thermal image defined in partial derivative fashion is the core contribution of this study. The thermal image of coal sample is obtained in real-life scenario by self-assembled thermographic camera in this study. The amalgamation between area segmentation, boundary detection and alarm series are described in abstract algebra. The principal objective of this paper is to understand the dependency pattern and the principles of working of image processing components and structure an inter-connected modelling technique also for those components with the help of mathematical foundation.
Mathematical Model for Tempering Time Effect on Quenched Steel Based on Hollomon Parameter
Institute of Scientific and Technical Information of China (English)
Nong WAN; Weihao XIONG; Jinping SUO
2005-01-01
Through the differentiating and integrating process, a mathematical model for tempering time effect on quenched steel was derived based on the attribute of state function and the general equation of Hollomon parameter, which correlates the tempering hardness with the tempering time at different tempering temperature. Using the established model, thelinear relationship between the tempering hardness and the tempering time in logarithm was proved theoretically, and the tempering hardness for various tempering time was reduced to the measurement and calculation of a hardness experiment tempered for 1 h at different tempering temperatures. Moreover, the hardness of steel 42CrMo and T8Mn tempered for various times at 200～600℃ was calculated using this method. The predicted results are in good agreement with those of the available experiments.
DEFF Research Database (Denmark)
Carugati, Andrea
. The resulting methodology builds on these four results. The methodology is based on an emergent and iterative process focused on the discussion of software prototypes built as boundary objects: visual, usable, bi-directional, and up-to-date. Iterations are kept short so that the prototypes remain simple enough...... modeling (AMM) in scheduling and control systems. Advanced mathematical techniques are relatively new in scheduling and control systems, at least in real production situations, and therefore the project included the research of methods and tools for the development of these systems. Because of the novelty...... with a relativist approach. Arriving at the design of an ISD methodology required the combination of previous theoretical results with the observations from the case study. The case study showed some of the key elements to be integrated in the methodology. Firstly, plans and models are subject of a high degree...
Authenticity of Mathematical Modeling
Tran, Dung; Dougherty, Barbara J.
2014-01-01
Some students leave high school never quite sure of the relevancy of the mathematics they have learned. They fail to see links between school mathematics and the mathematics of everyday life that requires thoughtful decision making and often complex problem solving. Is it possible to bridge the gap between school mathematics and the mathematics in…
Kartashev, Alexander; Safonov, Evgeniy; Kartasheva, Marina
2011-01-01
The mathematical model describing the operation of the installation of selfcontained heating and hot water supply based on solar thermal collector with the system of accumulation of heat energy, monitoring and control of thermal conditions of building is developed. Modeling of operation of the installation in different conditions is realized.
Dielectric Relaxation of Lanthanide-Based Ternary Oxides: Physical and Mathematical Models
Directory of Open Access Journals (Sweden)
Chun Zhao
2012-01-01
Full Text Available Cerium-doped hafnium oxides (CexHf1−xO2 and lanthanum-doped zirconium oxides (LaxZr1−xO2 were investigated. The highest dielectric constants, k, were obtained from lightly doped oxides with an La content of x=0.09 and a Ce content of x=0.1, for which k-values of 33~40 were obtained. The dielectric relaxation appears to be related to the size of crystal grains formed during annealing, which was dependent on the doping level. The physical and mathematical models were used to analyze the relationship between k-values and frequencies. The variations in the k-values up to megahertz frequencies for both CexHf1−xO2 and LaxZr1−xO2 are simulated based on the Curie-von Schweidler (CS or Havriliak-Negami (HN relationships. Concerning the lightly doped CexHf1−xO2 and LaxZr1−xO2, the data extracted are best modeled by the HN law, while LaxZr1−xO2 with doping level from x=0.22 to 0.63 are best modelled based on the CS law.
Ataei, Sh; Mahmud, Z.; Khalid, M. N.
2014-04-01
The students learning outcomes clarify what students should know and be able to demonstrate after completing their course. So, one of the issues on the process of teaching and learning is how to assess students' learning. This paper describes an application of the dichotomous Rasch measurement model in measuring the cognitive process of engineering students' learning of mathematics. This study provides insights into the perspective of 54 engineering students' cognitive ability in learning Calculus III based on Bloom's Taxonomy on 31 items. The results denote that some of the examination questions are either too difficult or too easy for the majority of the students. This analysis yields FIT statistics which are able to identify if there is data departure from the Rasch theoretical model. The study has identified some potential misfit items based on the measurement of ZSTD where the removal misfit item was accomplished based on the MNSQ outfit of above 1.3 or less than 0.7 logit. Therefore, it is recommended that these items be reviewed or revised to better match the range of students' ability in the respective course.
Chronology of DIC technique based on the fundamental mathematical modeling and dehydration impact.
Alias, Norma; Saipol, Hafizah Farhah Saipan; Ghani, Asnida Che Abd
2014-12-01
A chronology of mathematical models for heat and mass transfer equation is proposed for the prediction of moisture and temperature behavior during drying using DIC (Détente Instantanée Contrôlée) or instant controlled pressure drop technique. DIC technique has the potential as most commonly used dehydration method for high impact food value including the nutrition maintenance and the best possible quality for food storage. The model is governed by the regression model, followed by 2D Fick's and Fourier's parabolic equation and 2D elliptic-parabolic equation in a rectangular slice. The models neglect the effect of shrinkage and radiation effects. The simulations of heat and mass transfer equations with parabolic and elliptic-parabolic types through some numerical methods based on finite difference method (FDM) have been illustrated. Intel®Core™2Duo processors with Linux operating system and C programming language have been considered as a computational platform for the simulation. Qualitative and quantitative differences between DIC technique and the conventional drying methods have been shown as a comparative.
Han, Jinxiang; Huang, Jinzhao
2012-03-01
In this study, based on the resonator model and exciplex model of electromagnetic radiation within the human body, mathematical model of biological order state, also referred to as syndrome in traditional Chinese medicine, was established and expressed as: "Sy = v/ 1n(6I + 1)". This model provides the theoretical foundation for experimental research addressing the order state of living system, especially the quantitative research syndrome in traditional Chinese medicine.
Causality, mathematical models and statistical association: dismantling evidence-based medicine.
Thompson, R Paul
2010-04-01
From humble beginnings, largely at the medical school at McMaster University, Canada, the evidence-based medicine (EBM) movement has enjoyed a spectacular rise in international acceptance over the last 25 years. Randomized controlled trials (RCTs) and systematic reviews based on them have pride of place (the gold standard) in EBM's hierarchy of evidence; models and theories are relegated to the bottom of the hierarchy. In the last decade, RCTs have been extensively criticized. I briefly rehearse those criticisms because they are an important backdrop to the criticism of EBM developed in this paper. In essence, the argument developed here is that RCTs use mathematics solely as a tool of analysis rather than as the language of the science and that this fundamentally affects the validity of causal claims. As EBM gives pride of place to RCTs and devalues theoretical models - a devaluation that would be incomprehensible to a physicist or biologist - the validity of EBM's causal claims and knowledge claims are weak and far from a 'gold standard'.
Mathematical model for abrasive suspension jet cutting based on orthogonal test design
Institute of Scientific and Technical Information of China (English)
HU Gui-hua; ZHU Wen-hua; CAI Hong-xia; XU Chong; BAI Yu-jie; CHENG Jun; YUAN Jin; YU Tao
2009-01-01
This paper describes the application of orthogonal test design coupled with non-linear regression analysis to optimize abrasive suspension jet (AS J) cutting process and construct its cutting model. Orthogonal test design is applied to cutting stainless steel. Through range analysis on experiment results, the optimal process conditions for the cutting depth and the kerf ratio of the bottom width to the top width can be determined. In 'addition, the analysis of ranges and variances are all employed to identify various factors: traverse rate, working pressure, nozzle diameter, standoff distance which denote the importance order of the cutting parameters affecting cutting depth and the kerf ratio of the bottom width to the top width. Furthermore, non-linear regression analysis is used to establish the mathematical models of the cutting parameters based on the cutting depth and the kerf ratio. Finally, the verification experiments of cutting parameters' effect on cutting performance, which show that optimized cutting parameters and cutting model can significantly improve the prediction of the cutting ability and quality of ASJ.
Mathematical modelling in solid mechanics
Sofonea, Mircea; Steigmann, David
2017-01-01
This book presents new research results in multidisciplinary fields of mathematical and numerical modelling in mechanics. The chapters treat the topics: mathematical modelling in solid, fluid and contact mechanics nonconvex variational analysis with emphasis to nonlinear solid and structural mechanics numerical modelling of problems with non-smooth constitutive laws, approximation of variational and hemivariational inequalities, numerical analysis of discrete schemes, numerical methods and the corresponding algorithms, applications to mechanical engineering numerical aspects of non-smooth mechanics, with emphasis on developing accurate and reliable computational tools mechanics of fibre-reinforced materials behaviour of elasto-plastic materials accounting for the microstructural defects definition of structural defects based on the differential geometry concepts or on the atomistic basis interaction between phase transformation and dislocations at nano-scale energetic arguments bifurcation and post-buckling a...
Mathematical modeling with multidisciplinary applications
Yang, Xin-She
2013-01-01
Features mathematical modeling techniques and real-world processes with applications in diverse fields Mathematical Modeling with Multidisciplinary Applications details the interdisciplinary nature of mathematical modeling and numerical algorithms. The book combines a variety of applications from diverse fields to illustrate how the methods can be used to model physical processes, design new products, find solutions to challenging problems, and increase competitiveness in international markets. Written by leading scholars and international experts in the field, the
Mineral potential mapping with mathematical geological models
Porwal, A.K.
2006-01-01
Mathematical geological models are being increasingly used by natural resources delineation and planning agencies for mapping areas of mineral potential in order to optimize land use in accordance with socio-economic needs of the society. However, a key problem in spatial-mathematical-model-based mi
Modelling and Optimizing Mathematics Learning in Children
Käser, Tanja; Busetto, Alberto Giovanni; Solenthaler, Barbara; Baschera, Gian-Marco; Kohn, Juliane; Kucian, Karin; von Aster, Michael; Gross, Markus
2013-01-01
This study introduces a student model and control algorithm, optimizing mathematics learning in children. The adaptive system is integrated into a computer-based training system for enhancing numerical cognition aimed at children with developmental dyscalculia or difficulties in learning mathematics. The student model consists of a dynamic…
Mathematical modeling in chronobiology.
Bordyugov, G; Westermark, P O; Korenčič, A; Bernard, S; Herzel, H
2013-01-01
Circadian clocks are autonomous oscillators entrained by external Zeitgebers such as light-dark and temperature cycles. On the cellular level, rhythms are generated by negative transcriptional feedback loops. In mammals, the suprachiasmatic nucleus (SCN) in the anterior part of the hypothalamus plays the role of the central circadian pacemaker. Coupling between individual neurons in the SCN leads to precise self-sustained oscillations even in the absence of external signals. These neuronal rhythms orchestrate the phasing of circadian oscillations in peripheral organs. Altogether, the mammalian circadian system can be regarded as a network of coupled oscillators. In order to understand the dynamic complexity of these rhythms, mathematical models successfully complement experimental investigations. Here we discuss basic ideas of modeling on three different levels (1) rhythm generation in single cells by delayed negative feedbacks, (2) synchronization of cells via external stimuli or cell-cell coupling, and (3) optimization of chronotherapy.
Ruthven, Kenneth; Hennessy, Sara
2002-01-01
Analyzes the pedagogical ideas underpinning teachers' accounts of the successful use of computer-based tools and resources to support the teaching and learning of mathematics. Organizes central themes to form a pedagogical model capable of informing the use of such technologies in classroom teaching and generating theoretical conjectures for…
Directory of Open Access Journals (Sweden)
Loyko V. I.
2015-06-01
Full Text Available Agricultural producers interested in marketing of raw materials, whereas processing companies are interested in the establishment of raw material zones, providing capacity utilization; therefore, the establishment of sustainable linkages between producers and processors of raw materials is an objective necessity. In the article, with the help of mathematical methods we examine the conditions of mutually beneficial economic relations between agricultural producers and processing enterprises. Mathematical model for estimating the profits of the company is built of the following conditions: producers sell processing plants raw materials, determined by the coefficient of the interest in the partnership at an agreed purchase price, and the remaining raw materials are processed, so they can sell their products independently. Profit of the processing plant is determined by the mathematical model. To describe the nonlinear market-based sales of goods from its retail price we used a hyperbolic demand function
Mathematical model of orbital and ground-based cross-dispersion spectrographs
Yushkin, M. V.; Fatkhullin, T. A.; Panchuk, V. E.
2016-07-01
We present the technique and algorithm of numerical modeling of high-resolution spectroscopic equipment. The software is implemented in C++ using nVidia CUDA technology. We report the results of currently developedmodeling of new-generation echelle spectrographs. To validate the algorithms used to construct the mathematical model, we present the results of modeling of NES spectrograph of the 6-m telescope of the Special Astrophysical Observatory of the Russian Academy of Sciences. A comparison of simulated and real images of the spectra acquired with NES spectrograph demonstrates good agreement between the model constructed and experimental data.
Mathematical problems in meteorological modelling
Csomós, Petra; Faragó, István; Horányi, András; Szépszó, Gabriella
2016-01-01
This book deals with mathematical problems arising in the context of meteorological modelling. It gathers and presents some of the most interesting and important issues from the interaction of mathematics and meteorology. It is unique in that it features contributions on topics like data assimilation, ensemble prediction, numerical methods, and transport modelling, from both mathematical and meteorological perspectives. The derivation and solution of all kinds of numerical prediction models require the application of results from various mathematical fields. The present volume is divided into three parts, moving from mathematical and numerical problems through air quality modelling, to advanced applications in data assimilation and probabilistic forecasting. The book arose from the workshop “Mathematical Problems in Meteorological Modelling” held in Budapest in May 2014 and organized by the ECMI Special Interest Group on Numerical Weather Prediction. Its main objective is to highlight the beauty of the de...
Conceptualising inquiry based education in mathematics
DEFF Research Database (Denmark)
Blomhøj, Morten; Artigue, Michéle
2013-01-01
of inquiry as a pedagogical concept in the work of Dewey (e.g. 1916, 1938) to analyse and discuss its migration to science and mathematics education. For conceptualizing inquiry-based mathematics education (IBME) it is important to analyse how this concept resonates with already well-established theoretical......The terms inquiry-based learning (IBL) and inquiry-based education (IBE) have appeared with increasing frequency in educational policy and curriculum documents related to mathematics and science education over the past decade, indicating a major educational trend. We go back to the origin...... frameworks in mathematics education. Six such frameworks are analysed from the perspective of inquiry: the problem-solving tradition, the Theory of Didactical Situations, the Realistic Mathematics Education programme, the mathematical modelling perspective, the Anthropological Theory of Didactics...
Study of the Video Monitoring System Image Recognition Solutions Based on Mathematic models
Directory of Open Access Journals (Sweden)
Peilong Xu
2013-01-01
Full Text Available objective: Through establishment a set of image recognition system based on mathematic models, to develop a auto alarm solution for the video monitoring system. Methods: compare the images the video monitoring system collected according to the time sequences. Then after binaryzation and wave filtering, the images were converted into numerical values using autocorrelation function, and the alarm threshold value was confirmed by experiences. Results: Through experiments, the change ratios of the two images before and after image processing were inversely proportional to the autocorrelation function. When the function value is less than 0.8, it indicates that there is an object volumes larger than 1m3 has invaded into 15m distances, and when the function value is less than 0.6, it indicates that there is an object volumes larger than 1m3 has invaded into 30m distances. Conclusion: Through calculation of autocorrelation functions, auto alarm for the images collected by video monitoring system could be effectively realized.
Mathematical modeling of kidney transport.
Layton, Anita T
2013-01-01
In addition to metabolic waste and toxin excretion, the kidney also plays an indispensable role in regulating the balance of water, electrolytes, nitrogen, and acid-base. In this review, we describe representative mathematical models that have been developed to better understand kidney physiology and pathophysiology, including the regulation of glomerular filtration, the regulation of renal blood flow by means of the tubuloglomerular feedback mechanisms and of the myogenic mechanism, the urine concentrating mechanism, epithelial transport, and regulation of renal oxygen transport. We discuss the extent to which these modeling efforts have expanded our understanding of renal function in both health and disease.
Mathematical Model and Stability Analysis of Inverter-Based Distributed Generator
Directory of Open Access Journals (Sweden)
Alireza Khadem Abbasi
2013-01-01
Full Text Available This paper presents a mathematical (small-signal model of an electronically interfaced distributed generator (DG by considering the effect of voltage and frequency variations of the prime source. Dynamic equations are found by linearization about an operating point. In this study, the dynamic of DC part of the interface is included in the model. The stability analysis shows with proper selection of system parameters; the system is stable during steady-state and dynamic situations, and oscillatory modes are well damped. The proposed model is useful to study stability analysis of a standalone DG or a Microgrid.
Mathematical modeling of the human energy metabolism based on the Selfish Brain Theory.
Chung, Matthias; Göbel, Britta
2012-01-01
Deregulations in the human energy metabolism may cause diseases such as obesity and type 2 diabetes mellitus. The origins of these pathologies are fairly unknown. The key role of the brain is the regulation of the complex whole body energy metabolism. The Selfish Brain Theory identifies the priority of brain energy supply in the competition for available energy resources within the organism. Here, we review mathematical models of the human energy metabolism supporting central aspects of the Selfish Brain Theory. First, we present a dynamical system modeling the whole body energy metabolism. This model takes into account the two central control mechanisms of the brain, i.e., allocation and appetite. Moreover, we present mathematical models of regulatory subsystems. We examine a neuronal model which specifies potential elements of the brain to sense and regulate cerebral energy content. We investigate a model of the HPA system regulating the allocation of energy within the organism. Finally, we present a robust modeling approach of appetite regulation. All models account for a systemic understanding of the human energy metabolism and thus do shed light onto defects causing metabolic diseases.
Java Based Computer Algorithms for the Solution of a Business Mathematics Model
Directory of Open Access Journals (Sweden)
A. D. Chinedu
2014-10-01
Full Text Available A novel approach is proposed as a framework for working out uncertainties associated with decisions between the choices of leasing and procurement of capital assets in a manufacturing industry. The mathematical concept of the tool is discussed while the technique adopted is much simpler to implement and initialize. The codes were developed in Java-programming language and text-run and executed on a computer system running on Windows 7 operating system. This was done in order to solve a model that illustrates a case study in actuarial mathematics. Meanwhile the solution obtained proves to be stable and proffers to suit the growing frenzy for software for similar recurring cases in business. In addition, it speeds up the computational results. The results obtained using the empirical method is compared with the output and adjudged excellent in terms of accuracy and adoption.
Roduta Roberts, Mary; Alves, Cecilia B.; Chu, Man-Wai; Thompson, Margaret; Bahry, Louise M.; Gotzmann, Andrea
2014-01-01
The purpose of this study was to evaluate the adequacy of three cognitive models, one developed by content experts and two generated from student verbal reports for explaining examinee performance on a grade 3 diagnostic mathematics test. For this study, the items were developed to directly measure the attributes in the cognitive model. The…
Mathematical Model for Hit Phenomena
Ishii, Akira; Hayashi, Takefumi; Matsuda, Naoya; Nakagawa, Takeshi; Arakaki, Hisashi; Yoshida, Narihiko
2010-01-01
The mathematical model for hit phenomena in entertainments is presented as a nonlinear, dynamical and non-equilibrium phenomena. The purchase intention for each person is introduced and direct and indirect communications are expressed as two-body and three-body interaction in our model. The mathematical model is expressed as coupled nonlinear differential equations. The important factor in the model is the decay time of rumor for the hit. The calculated results agree very well with revenues of recent 25 movies.
Pace, Sydney
2000-01-01
Presents a methodology for teaching mathematical modeling skills to A-level students. Gives an example illustrating how mathematics teachers and design teachers can take joint perspective in devising learning opportunities that develop mathematical and design skills concurrently. (Contains 14 references.) (Author/ASK)
Juska, Alfonsas; Gedminiene, Genovaite; Ivanec, Ruta
2006-01-01
This paper has arisen as a result of teaching Models in Biology to undergraduates of Bioengineering at the Gediminas Technical University of Vilnius. The aim is to teach the students to use a fresh approach to the problems they are familiar with, to come up with an articulate verbal model after a mental effort, to express it in rigorous…
Explorations in Elementary Mathematical Modeling
Directory of Open Access Journals (Sweden)
Mazen Shahin
2010-06-01
Full Text Available In this paper we will present the methodology and pedagogy of Elementary Mathematical Modeling as a one-semester course in the liberal arts core. We will focus on the elementary models in finance and business. The main mathematical tools in this course are the difference equations and matrix algebra. We also integrate computer technology and cooperative learning into this inquiry-based learning course where students work in small groups on carefully designed activities and utilize available software to support problem solving and understanding of real life situations. We emphasize the use of graphical and numerical techniques, rather than theoretical techniques, to investigate and analyze the behavior of the solutions of the difference equations.As an illustration of our approach, we will show a nontraditional and efficient way of introducing models from finance and economics. We will also present an interesting model of supply and demand with a lag time, which is called the cobweb theorem in economics. We introduce a sample of a research project on a technique of removing chaotic behavior from a chaotic system.
Mathematical Models of Biochemical Oscillations
Conrad, Emery David
1999-01-01
The goal of this paper is to explain the mathematics involved in modeling biochemical oscillations. We first discuss several important biochemical concepts fundamental to the construction of descriptive mathematical models. We review the basic theory of differential equations and stability analysis as it relates to two-variable models exhibiting oscillatory behavior. The importance of the Hopf Bifurcation will be discussed in detail for the central role it plays in limit cycle behavior and...
Mathematical modelling of cucumber (cucumis sativus) drying
Shahari, N.; Hussein, S. M.; Nursabrina, M.; Hibberd, S.
2014-07-01
This paper investigates the applicability of using an experiment based mathematical model (empirical model) and a single phase mathematical model with shrinkage to describe the drying curve of cucumis sativus (cucumber). Drying experiments were conducted using conventional air drying and data obtained from these experiments were fitted to seven empirical models using non-linear least square regression based on the Levenberg Marquardt algorithm. The empirical models were compared according to their root mean square error (RMSE), sum of square error (SSE) and coefficient of determination (R2). A logarithmic model was found to be the best empirical model to describe the drying curve of cucumber. The numerical result of a single phase mathematical model with shrinkage was also compared with experiment data for cucumber drying. A good agreement was obtained between the model predictions and the experimental data.
Mathematical Models of Waiting Time.
Gordon, Sheldon P.; Gordon, Florence S.
1990-01-01
Considered are several mathematical models that can be used to study different waiting situations. Problems involving waiting at a red light, bank, restaurant, and supermarket are discussed. A computer program which may be used with these problems is provided. (CW)
A QFD-Based Mathematical Model for New Product Development Considering the Target Market Segment
Directory of Open Access Journals (Sweden)
Liang-Hsuan Chen
2014-01-01
Full Text Available Responding to customer needs is important for business success. Quality function deployment provides systematic procedures for converting customer needs into technical requirements to ensure maximum customer satisfaction. The existing literature mainly focuses on the achievement of maximum customer satisfaction under a budgetary limit via mathematical models. The market goal of the new product for the target market segment is usually ignored. In this study, the proposed approach thus considers the target customer satisfaction degree for the target market segment in the model by formulating the overall customer satisfaction as a function of the quality level. In addition, the proposed approach emphasizes the cost-effectiveness concept in the design stage via the achievement of the target customer satisfaction degree using the minimal total cost. A numerical example is used to demonstrate the applicability of the proposed approach and its characteristics are discussed.
Mathematical model of cylindrical form tolerance
Institute of Scientific and Technical Information of China (English)
蔡敏; 杨将新; 吴昭同
2004-01-01
Tolerance is essential for integration of CAD and CAM. Unfortunately, the meaning of tolerances in the national standard is expressed in graphical and language forms and is not adaptable for expression, processing and data transferring with computers. How to interpret its semantics is becoming a focus of relevant studies. This work based on the mathematical definition of form tolerance in ANSI Y 14.5.1 M-1994, established the mathematical model of form tolerance for cylindrical feature. First, each tolerance in the national standard was established by vector equation. Then on the foundation of toler-ance's mathematical definition theory, each tolerance zone's mathematical model was established by inequality based on degrees of feature. At last the variance area of each tolerance zone is derived. This model can interpret the semantics of form tolerance exactly and completely.
Mathematical model of cylindrical form tolerance
Institute of Scientific and Technical Information of China (English)
蔡敏; 杨将新; 吴昭同
2004-01-01
Tolerance is essential for integration of CAD and CAM.Unfortunately,the meaning of tolerances in the national standard is expressed in graphical and language forms and is not adaptable for expression,processing and data transferring with computers.How to interpret its semantics is becoming a focus of relevant studies.This work based on the mathematical definition of form tolerance in ANSI Y 14.5.1 M-1994,established the mathematical model of form tolerance for cylindrical feature.First,each tolerance in the national standard was established by vector equation.Then on the foundation of tolerance's mathematical definition theory,each tolerance zone's mathematical model was established by inequality based on degrees of feature.At last the variance area of each tolerance zone is derived.This model can interpret the semantics of form tolerance exactly and completely.
The Spectrum of Mathematical Models.
Karplus, Walter J.
1983-01-01
Mathematical modeling problems encountered in many disciplines are discussed in terms of the modeling process and applications of models. The models are classified according to three types of abstraction: continuous-space-continuous-time, discrete-space-continuous-time, and discrete-space-discrete-time. Limitations in different kinds of modeling…
Annual Perspectives in Mathematics Education 2016: Mathematical Modeling and Modeling Mathematics
Hirsch, Christian R., Ed.; McDuffie, Amy Roth, Ed.
2016-01-01
Mathematical modeling plays an increasingly important role both in real-life applications--in engineering, business, the social sciences, climate study, advanced design, and more--and within mathematics education itself. This 2016 volume of "Annual Perspectives in Mathematics Education" ("APME") focuses on this key topic from a…
Yuliani, Kiki; Saragih, Sahat
2015-01-01
The purpose of this research was to: 1) development of learning devices based guided discovery model in improving of understanding concept and critical thinking mathematically ability of students at Islamic Junior High School; 2) describe improvement understanding concept and critical thinking mathematically ability of students at MTs by using…
Teaching mathematical modelling through project work
DEFF Research Database (Denmark)
Blomhøj, Morten; Kjeldsen, Tinne Hoff
2006-01-01
are reported in manners suitable for internet publication for colleagues. The reports and the related discussions reveal interesting dilemmas concerning the teaching of mathematical modelling and how to cope with these through “setting the scene” for the students modelling projects and through dialogues...... in their own classes, evaluate and report a project based problem oriented course in mathematical modelling. The in-service course runs over one semester and includes three seminars of 3, 1 and 2 days. Experiences show that the course objectives in general are fulfilled and that the course projects......The paper presents and analyses experiences from developing and running an in-service course in project work and mathematical modelling for mathematics teachers in the Danish gymnasium, e.g. upper secondary level, grade 10-12. The course objective is to support the teachers to develop, try out...
Complex networks and SOA: Mathematical modelling of granularity based web service compositions
Indian Academy of Sciences (India)
S Chatla; S Kadam; D Kolluru; S Sinha; A Viswandhuni; A Vaidya
2011-08-01
Service Oriented Architecture (SOA) can be deﬁned as a way of deﬁning and implementing enterprise applications that deals with the intercommunication of loosely coupled, coarse grained (business level), reusable artifacts (services). In this paper, we attempt to mathematically model the preliminary steps in the larger problem of providing an optimal architecture. The problem is treated as a complex network, particularly a process-task-network. We employ statistical and graph-theoretic methods namely, Jaccard’s distance analysis, Multiple Correspondence method and the Minimum Spanning Tree method, to ﬁnd appropriate clusters. These methods are used to cluster tasks across business processes to propose services. Additional properties and features of these clusters are discussed. We propose a leverage factor which demonstrates the importance of a task within the service and its impact on service composition.
A new mathematical modelling based shape extraction technique for Forensic Odontology.
G, Jaffino; A, Banumathi; Gurunathan, Ulaganathan; B, Vijayakumari; J, Prabin Jose
2017-02-28
Forensic Odontology is a specific means for identifying a person in which deceased, and particularly in fatality incidents. The algorithm can be proposed to identify a person by comparing both postmortem (PM) and antemortem (AM) dental radiographs and photographs. This work aims to introduce a new mathematical algorithm for photographs in addition with radiographs. Isoperimetric graph partitioning method is used to extract the shape of dental images in forensic identification. Shape matching is done by comparing AM and PM dental images using both similarity and distance measures. Experimental results prove that the higher matching distance is observed by distance metric rather than similarity measures. The results of this algorithm show that a high hit rate is observed for distance based performance measures and it is well suited for forensic odontologist to identify a person.
Alba-Martínez, Jose; Trujillo, Macarena; Blasco-Gimenez, Ramon; Berjano, Enrique
2012-01-01
Radiofrequency cardiac ablation (RFCA) has been used to treat certain types of cardiac arrhythmias by producing a thermal lesion. Even though a tissue temperature higher than 50ºC is required to destroy the target, thermal mapping is not currently used during RFCA. Our aim was thus to develop mathematical models capable of estimating tissue temperature from tissue characteristics acquired or estimated at the beginning of the procedure (electrical conductivity, thermal conductivity, specific heat and density) and the applied voltage at any time. Biological tissue was considered as a system with an input (applied voltage) and output (tissue temperature), and so the mathematical models were based on transfer functions relating these variables. We used theoretical models based on finite element method to verify the mathematical models. Firstly, we solved finite element models to identify the transfer functions between the temperature at a depth of 4 mm and a constant applied voltage using a 7Fr and 4 mm electrode. The results showed that the relationships can be expressed as first-order transfer functions. Changes in electrical conductivity only affected the static gain of the system, while specific heat variations produced a change in the dynamic system response. In contrast, variations in thermal conductivity modified both the static gain and the dynamic system response. Finally, to assess the performance of the transfer functions obtained, we conducted a new set of computer simulations using a controlled temperature protocol and considering the temperature dependence of the thermal and electrical conductivities, i.e. conditions closer to those found in clinical use. The results showed that the difference between the values estimated from transfer functions and the temperatures obtained from finite element models was less than 4ºC, which suggests that the proposed method could be used to estimate tissue temperature in real time.
Ping, Qingyun; Abu-Reesh, Ibrahim M; He, Zhen
2016-11-01
Boron removal is an arising issue in desalination plants due to boron's toxicity. As an emerging treatment concept, bioelectrochemical systems (BES) can achieve potentially cost-effective boron removal by taking advantage of cathodic-produced alkali. Prior studies have demonstrated successful removal of boron in microbial desalination cells (MDCs) and microbial fuel cells (MFCs), both of which are representative BES. Herein, mathematical models were developed to further evaluate boron removal by different BES and understand the key operating factors. The models delivered very good prediction of the boron concentration in the MDC integrated with Donnan Dialysis (DD) system with the lowest relative root-mean-square error (RMSE) of 0.00%; the predication of the MFC performance generated the highest RMSE of 18.55%. The model results of salt concentration, solution pH, and current generation were well fitted with experimental data for RMSE values mostly below 10%. The long term simulation of the MDC-DD system suggests that the accumulation of salt in the catholyte/stripping solution could have a positive impact on the removal of boron due to osmosis-driven convection. The current generation in the MDC may have little influence on the boron removal, while in the MFC the current-driven electromigration can contribute up to 40% of boron removal. Osmosis-induced convection transport of boron could be the major driving force for boron removal to a low level 22.2 in order to avoid boron accumulation in the anolyte effluent.
Mathematics Teachers' Ideas about Mathematical Models: A Diverse Landscape
Bautista, Alfredo; Wilkerson-Jerde, Michelle H.; Tobin, Roger G.; Brizuela, Bárbara M.
2014-01-01
This paper describes the ideas that mathematics teachers (grades 5-9) have regarding mathematical models of real-world phenomena, and explores how teachers' ideas differ depending on their educational background. Participants were 56 United States in-service mathematics teachers. We analyzed teachers' written responses to three open-ended…
Solovyova, N. V.; Lobkovsky, L. I.
2015-09-01
This paper proposes a method of mathematical modelling of ecological risk based on a synthesis of dynamic and probabilistic risk assessment techniques. The probability of assessment of an acceptable probability of an anthropogenic impact to minimize economic costs is proposed. The dependence of an acceptable probability of an anthropogenic impact on the ecological risk is demonstrated with an example calculation. The results of the modelling of the state of a shelf ecosystem based on the dynamic model are used for the calculation as source information. Based on this synthesis, the calculation results bring about the opportunity to balance ecological-economic goals of achieving safe development of the shelf and to satisfy the involuntary necessity to reduce the costs on environmental protection measures, while maintaining the priority of environmental requirements.
Mathematical modeling in soil science
Tarquis, Ana M.; Gasco, Gabriel; Saa-Requejo, Antonio; Méndez, Ana; Andina, Diego; Sánchez, M. Elena; Moratiel, Rubén; Antón, Jose Manuel
2015-04-01
Teaching in context can be defined as teaching a mathematical idea or process by using a problem, situation, or data to enhance the teaching and learning process. The same problem or situation may be used many times, at different mathematical levels to teach different objectives. A common misconception exists that assigning/teaching applications is teaching in context. While both use problems, the difference is in timing, in purpose, and in student outcome. In this work, one problem situation is explored thoroughly at different levels of understanding and other ideas are suggested for classroom explorations. Some teachers, aware of the difficulties some students have with mathematical concepts, try to teach quantitative sciences without using mathematical tools. Such attempts are not usually successful. The answer is not in discarding the mathematics, but in finding ways to teach mathematically-based concepts to students who need them but who find them difficult. The computer is an ideal tool for this purpose. To this end, teachers of the Soil Science and Mathematics Departments of the UPM designed a common practice to teach to the students the role of soil on the carbon sequestration. The objective of this work is to explain the followed steps to the design of the practice. Acknowledgement Universidad Politécnica de Madrid (UPM) for the Projects in Education Innovation IE12_13-02009 and IE12_13-02012 is gratefully acknowledge.
Dambacher, Jeffrey M; Rothlisberg, Peter C; Loneragan, Neil R
2015-01-01
A major decline in the catch of the banana prawn [shrimp], Penaeus (Fenneropenaeus) merguiensis, occurred over a six-year period in the Weipa region of the northeastern Gulf of Carpentaria, Australia. Three main hypotheses have been developed to explain this decline: (1) prawn recruitment collapsed due to overfishing; (2) recruitment collapsed due to a change in the prawn's environment; and (3) adult banana prawns were still present, but fishers could no longer effectively find or catch them. Qualitative mathematical models were used to link population biology, environmental factors, and fishery dynamics to evaluate the alternative hypotheses. This modeling approach provides the means to rapidly integrate knowledge across disciplines and consider alternative hypotheses about how the structure and function of an ecosystem affects its dynamics. Alternative models were constructed to address the different hypotheses and also to encompass a diversity of opinion about the underlying dynamics of the system. Key findings from these analyses are that: instability in the system can arise when discarded fishery bycatch supports relatively high predation pressure; system stability can be enhanced by management of fishing effort or stock catchability; catch per unit effort is not necessarily a reliable indicator of stock abundance; a change in early-season rainfall should affect all stages in the banana prawn's life cycle; and a reduced catch in the Weipa region can create and reinforce a shift in fishing effort away from Weipa. Results from the models informed an approach to test the hypotheses (i.e., an experimental fishing program), and promoted understanding of the system among researchers, management agencies, and industry. The analytical tools developed in this work to address stages of a prawn life cycle and fishery dynamics are generally applicable to any exploited natural. resource.
Mathematical model for bone mineralization
Directory of Open Access Journals (Sweden)
Svetlana V Komarova
2015-08-01
Full Text Available Defective bone mineralization has serious clinical manifestations, including deformities and fractures, but the regulation of this extracellular process is not fully understood. We have developed a mathematical model consisting of ordinary differential equations that describe collagen maturation, production and degradation of inhibitors, and mineral nucleation and growth. We examined the roles of individual processes in generating normal and abnormal mineralization patterns characterized using two outcome measures: mineralization lag time and degree of mineralization. Model parameters describing the formation of hydroxyapatite mineral on the nucleating centers most potently affected the degree of mineralization, while the parameters describing inhibitor homeostasis most effectively changed the mineralization lag time. Of interest, a parameter describing the rate of matrix maturation emerged as being capable of counter-intuitively increasing both the mineralization lag time and the degree of mineralization. We validated the accuracy of model predictions using known diseases of bone mineralization such as osteogenesis imperfecta and X-linked hypophosphatemia. The model successfully describes the highly non-linear mineralization dynamics, which includes an initial lag phase when osteoid is present but no mineralization is evident, then fast primary mineralization, followed by secondary mineralization characterized by a continuous slow increase in bone mineral content. The developed model can potentially predict the function for a mutated protein based on the histology of pathologic bone samples from mineralization disorders of unknown etiology.
Mathematical models in biology bringing mathematics to life
Ferraro, Maria; Guarracino, Mario
2015-01-01
This book presents an exciting collection of contributions based on the workshop “Bringing Maths to Life” held October 27-29, 2014 in Naples, Italy. The state-of-the art research in biology and the statistical and analytical challenges facing huge masses of data collection are treated in this Work. Specific topics explored in depth surround the sessions and special invited sessions of the workshop and include genetic variability via differential expression, molecular dynamics and modeling, complex biological systems viewed from quantitative models, and microscopy images processing, to name several. In depth discussions of the mathematical analysis required to extract insights from complex bodies of biological datasets, to aid development in the field novel algorithms, methods and software tools for genetic variability, molecular dynamics, and complex biological systems are presented in this book. Researchers and graduate students in biology, life science, and mathematics/statistics will find the content...
The 24-Hour Mathematical Modeling Challenge
Galluzzo, Benjamin J.; Wendt, Theodore J.
2015-01-01
Across the mathematics curriculum there is a renewed emphasis on applications of mathematics and on mathematical modeling. Providing students with modeling experiences beyond the ordinary classroom setting remains a challenge, however. In this article, we describe the 24-hour Mathematical Modeling Challenge, an extracurricular event that exposes…
Mathematical Modeling: A Bridge to STEM Education
Kertil, Mahmut; Gurel, Cem
2016-01-01
The purpose of this study is making a theoretical discussion on the relationship between mathematical modeling and integrated STEM education. First of all, STEM education perspective and the construct of mathematical modeling in mathematics education is introduced. A review of literature is provided on how mathematical modeling literature may…
A mathematical model of forgetting and amnesia
Murre, J.M.J.; Chessa, A.G.; Meeter, M.
2013-01-01
We describe a mathematical model of learning and memory and apply it to the dynamics of forgetting and amnesia. The model is based on the hypothesis that the neural systems involved in memory at different time scales share two fundamental properties: (1) representations in a store decline in strengt
Modeling interdisciplinary activities involving Mathematics
DEFF Research Database (Denmark)
Iversen, Steffen Møllegaard
2006-01-01
In this paper a didactical model is presented. The goal of the model is to work as a didactical tool, or conceptual frame, for developing, carrying through and evaluating interdisciplinary activities involving the subject of mathematics and philosophy in the high schools. Through the terms...... domains (Michelsen, 2001, 2005a, 2005b). Furthermore the theoretical description rest on a series of qualitative interviews with teachers from the Danish high school (grades 9-11) conducted recently. The special case of concrete interdisciplinary activities between mathematics and philosophy is also...
Mathematical modelling of membrane separation
DEFF Research Database (Denmark)
Vinther, Frank
This thesis concerns mathematical modelling of membrane separation. The thesis consists of introductory theory on membrane separation, equations of motion, and properties of dextran, which will be the solute species throughout the thesis. Furthermore, the thesis consist of three separate...... mathematical models, each with a different approach to membrane separation. The first model is a statistical model investigating the interplay between solute shape and the probability of entering the membrane. More specific the transition of solute particles from being spherical to becoming more elongated...... as prolate ellipsoids with the same volume. The porous membrane is assumed isotropic such that the model reduces to a two dimensional model. With this assumption ellipsoids with the same volume reduces to ellipses with the same area. The model finds the probability of entering the pore of the membrane...
Lee, Taek-Soo; Frey, Eric C; Tsui, Benjamin M W
2015-04-07
This paper presents two 4D mathematical observer models for the detection of motion defects in 4D gated medical images. Their performance was compared with results from human observers in detecting a regional motion abnormality in simulated 4D gated myocardial perfusion (MP) SPECT images. The first 4D mathematical observer model extends the conventional channelized Hotelling observer (CHO) based on a set of 2D spatial channels and the second is a proposed model that uses a set of 4D space-time channels. Simulated projection data were generated using the 4D NURBS-based cardiac-torso (NCAT) phantom with 16 gates/cardiac cycle. The activity distribution modelled uptake of (99m)Tc MIBI with normal perfusion and a regional wall motion defect. An analytical projector was used in the simulation and the filtered backprojection (FBP) algorithm was used in image reconstruction followed by spatial and temporal low-pass filtering with various cut-off frequencies. Then, we extracted 2D image slices from each time frame and reorganized them into a set of cine images. For the first model, we applied 2D spatial channels to the cine images and generated a set of feature vectors that were stacked for the images from different slices of the heart. The process was repeated for each of the 1,024 noise realizations, and CHO and receiver operating characteristics (ROC) analysis methodologies were applied to the ensemble of the feature vectors to compute areas under the ROC curves (AUCs). For the second model, a set of 4D space-time channels was developed and applied to the sets of cine images to produce space-time feature vectors to which the CHO methodology was applied. The AUC values of the second model showed better agreement (Spearman's rank correlation (SRC) coefficient = 0.8) to human observer results than those from the first model (SRC coefficient = 0.4). The agreement with human observers indicates the proposed 4D mathematical observer model provides a good predictor of the
Lee, Taek-Soo; Frey, Eric C.; Tsui, Benjamin M. W.
2015-04-01
This paper presents two 4D mathematical observer models for the detection of motion defects in 4D gated medical images. Their performance was compared with results from human observers in detecting a regional motion abnormality in simulated 4D gated myocardial perfusion (MP) SPECT images. The first 4D mathematical observer model extends the conventional channelized Hotelling observer (CHO) based on a set of 2D spatial channels and the second is a proposed model that uses a set of 4D space-time channels. Simulated projection data were generated using the 4D NURBS-based cardiac-torso (NCAT) phantom with 16 gates/cardiac cycle. The activity distribution modelled uptake of 99mTc MIBI with normal perfusion and a regional wall motion defect. An analytical projector was used in the simulation and the filtered backprojection (FBP) algorithm was used in image reconstruction followed by spatial and temporal low-pass filtering with various cut-off frequencies. Then, we extracted 2D image slices from each time frame and reorganized them into a set of cine images. For the first model, we applied 2D spatial channels to the cine images and generated a set of feature vectors that were stacked for the images from different slices of the heart. The process was repeated for each of the 1,024 noise realizations, and CHO and receiver operating characteristics (ROC) analysis methodologies were applied to the ensemble of the feature vectors to compute areas under the ROC curves (AUCs). For the second model, a set of 4D space-time channels was developed and applied to the sets of cine images to produce space-time feature vectors to which the CHO methodology was applied. The AUC values of the second model showed better agreement (Spearman’s rank correlation (SRC) coefficient = 0.8) to human observer results than those from the first model (SRC coefficient = 0.4). The agreement with human observers indicates the proposed 4D mathematical observer model provides a good predictor of the
Mathematical Model for Photovoltaic Cells
Directory of Open Access Journals (Sweden)
Wafaa ABD EL-BASIT
2013-11-01
Full Text Available The study of photovoltaic systems in an efficient manner requires a precise knowledge of the (I-V and (P-V characteristic curves of photovoltaic modules. So, the aim of the present paper is to estimate such characteristics based on different operating conditions. In this concern, a simple one diode mathematical model was implemented using MATLAB script. The output characteristics of PV cell depend on the environmental conditions. For any solar cell, the model parameters are function of the irradiance and the temperature values of the site where the panel is placed. In this paper, the numerical values of the equivalent circuit parameters are generated by the program. As well, the dependence of the cells electrical parameters are analyzed under the influence of different irradiance and temperature levels. The variation of slopes of the (I–V curves of a cell at short-circuit and open-circuit conditions with intensity of illumination in small span of intensity and different temperature levels have been applied to determine the cell parameters, shunt resistance, series resistance. The results show that the efficiency of solar cells has an inverse relationship with temperature, irradiance levels are affected by the change of the photo-generation current and the series resistance in the single diode model.
Mathematical modeling and optimization of complex structures
Repin, Sergey; Tuovinen, Tero
2016-01-01
This volume contains selected papers in three closely related areas: mathematical modeling in mechanics, numerical analysis, and optimization methods. The papers are based upon talks presented on the International Conference for Mathematical Modeling and Optimization in Mechanics, held in Jyväskylä, Finland, March 6-7, 2014 dedicated to Prof. N. Banichuk on the occasion of his 70th birthday. The articles are written by well-known scientists working in computational mechanics and in optimization of complicated technical models. Also, the volume contains papers discussing the historical development, the state of the art, new ideas, and open problems arising in modern continuum mechanics and applied optimization problems. Several papers are concerned with mathematical problems in numerical analysis, which are also closely related to important mechanical models. The main topics treated include: * Computer simulation methods in mechanics, physics, and biology; * Variational problems and methods; minimiz...
Mathematical Properties Relevant to Geomagnetic Field Modeling
DEFF Research Database (Denmark)
Sabaka, Terence J.; Hulot, Gauthier; Olsen, Nils
2010-01-01
properties of those spatial mathematical representations are also discussed, especially in view of providing a formal justification for the fact that geomagnetic field models can indeed be constructed from ground-based and satellite-born observations, provided those reasonably approximate the ideal......Geomagnetic field modeling consists in converting large numbers of magnetic observations into a linear combination of elementary mathematical functions that best describes those observations.The set of numerical coefficients defining this linear combination is then what one refers...... be directly measured. In this chapter, the mathematical foundation of global (as opposed to regional) geomagnetic field modeling is reviewed, and the spatial modeling of the field in spherical coordinates is focussed. Time can be dealt with as an independent variable and is not explicitly considered...
Mathematical Properties Relevant to Geomagnetic Field Modeling
DEFF Research Database (Denmark)
Sabaka, Terence J.; Hulot, Gauthier; Olsen, Nils
2014-01-01
properties of those spatial mathematical representations are also discussed, especially in view of providing a formal justification for the fact that geomagnetic field models can indeed be constructed from ground-based and satellite-born observations, provided those reasonably approximate the ideal situation......Geomagnetic field modeling consists in converting large numbers of magnetic observations into a linear combination of elementary mathematical functions that best describes those observations. The set of numerical coefficients defining this linear combination is then what one refers...... be directly measured. In this chapter, the mathematical foundation of global (as opposed to regional) geomagnetic field modeling is reviewed, and the spatial modeling of the field in spherical coordinates is focused. Time can be dealt with as an independent variable and is not explicitly considered...
Mathematical modeling of biological processes
Friedman, Avner
2014-01-01
This book on mathematical modeling of biological processes includes a wide selection of biological topics that demonstrate the power of mathematics and computational codes in setting up biological processes with a rigorous and predictive framework. Topics include: enzyme dynamics, spread of disease, harvesting bacteria, competition among live species, neuronal oscillations, transport of neurofilaments in axon, cancer and cancer therapy, and granulomas. Complete with a description of the biological background and biological question that requires the use of mathematics, this book is developed for graduate students and advanced undergraduate students with only basic knowledge of ordinary differential equations and partial differential equations; background in biology is not required. Students will gain knowledge on how to program with MATLAB without previous programming experience and how to use codes in order to test biological hypothesis.
Quality Prediction and Control of Reducing Pipe Based on EOS-ELM-RPLS Mathematics Modeling Method
Directory of Open Access Journals (Sweden)
Dong Xiao
2014-01-01
Full Text Available The inspection of inhomogeneous transverse and longitudinal wall thicknesses, which determines the quality of reducing pipe during the production of seamless steel reducing pipe, is lags and difficult to establish its mechanism model. Aiming at the problems, we proposed the quality prediction model of reducing pipe based on EOS-ELM-RPLS algorithm, which taking into account the production characteristics of its time-varying, nonlinearity, rapid intermission, and data echelon distribution. Key contents such as analysis of data time interval, solving of mean value, establishment of regression model, and model online prediction were introduced and the established prediction model was used in the quality prediction and iteration control of reducing pipe. It is shown through experiment and simulation that the prediction and iteration control method based on EOS-ELM-RPLS model can effectively improve the quality of steel reducing pipe, and, moreover, its maintenance cost was low and it has good characteristics of real time, reliability, and high accuracy.
Mathematical Modeling of Cellular Metabolism.
Berndt, Nikolaus; Holzhütter, Hermann-Georg
2016-01-01
Cellular metabolism basically consists of the conversion of chemical compounds taken up from the extracellular environment into energy (conserved in energy-rich bonds of organic phosphates) and a wide array of organic molecules serving as catalysts (enzymes), information carriers (nucleic acids), and building blocks for cellular structures such as membranes or ribosomes. Metabolic modeling aims at the construction of mathematical representations of the cellular metabolism that can be used to calculate the concentration of cellular molecules and the rates of their mutual chemical interconversion in response to varying external conditions as, for example, hormonal stimuli or supply of essential nutrients. Based on such calculations, it is possible to quantify complex cellular functions as cellular growth, detoxification of drugs and xenobiotic compounds or synthesis of exported molecules. Depending on the specific questions to metabolism addressed, the methodological expertise of the researcher, and available experimental information, different conceptual frameworks have been established, allowing the usage of computational methods to condense experimental information from various layers of organization into (self-) consistent models. Here, we briefly outline the main conceptual frameworks that are currently exploited in metabolism research.
Institute of Scientific and Technical Information of China (English)
Gao Ning; Sun Wei
2015-01-01
Based on the study of supply chain (SC) and SC optimization in engineering projects, a mixed integer nonlinear programming (MINLP) optimization model is developed to minimize the total SC cost for international petrochemical en-gineering projects. A steam cracking project is selected and analyzed, from which typical SC characteristics in international engineering projects in the area of petrochemical industry are summarized. The MINLP model is therefore developed and applied to projects with detailed data. The optimization results are analyzed and compared by the MINLP model, indicat-ing that they are appropriate to SC management practice in engineering projects, and are consistent with the optimal price-effective strategy in procurement. As a result, the model could provide useful guidance to SC optimization of international engineering projects in petrochemical industry, and improve SC management by selecting more reliable and qualiifed part-ner enterprises in SC for the project.
Faria, Ana; Bateira, Carlos; Laura, Soares; Fernandes, Joana; Gonçalves, José; Marques, Fernando
2016-04-01
The work focuses the evaluation of landslide susceptibility in Douro Region agricultural terraces, supported by dry stone walls and earth embankments, using two physically based models. The applied models, SHALSTAB (Montgomery et al.,1994; Dietrich et al., 1995) and SINMAP (PACK et al., 2005), combine an infinite slope stability model with a steady state hydrological model, and both use the following geophysical parameters: cohesion, friction angle, specific weight and soil thickness. The definition of the contributing areas is different in both models. The D∞ methodology used by SINMAP model suggests a great influence of the terraces morphology, providing a much more diffuse flow on the internal flow modelling. The MD8 used in SHALSTAB promotes an important degree of flow concentration, representing an internal flow based on preferential paths of the runoff as the areas more susceptible to saturation processes. The model validation is made through the contingency matrix method (Fawcett, 2006; Raia et al., 2014) and implies the confrontation with the inventory of past landslides. The True Positive Rate shows that SHALSTAB classifies 77% of the landslides on the high susceptibility areas, while SINMAP reaches 90%. The SINMAP has a False Positive Rate (represents the percentage of the slipped area that is classified as unstable but without landslides) of 83% and the SHALSTAB has 67%. The reliability (analyzes the areas that were correctly classified on the total area) of SHALSTAB is better (33% against 18% of SINMAP). Relative to Precision (refers to the ratio of the slipped area correctly classified over the whole area classified as unstable) SHALSTAB has better results (0.00298 against 0.00283 of SINMAP). It was elaborate the index TPR/FPR and better results obtained by SHALSTAB (1.14 against 1.09 of SINMAP). SHALSTAB shows a better performance in the definition of susceptibility most prone areas to instability processes. One of the reasons for the difference of
Category Theory as a Formal Mathematical Foundation for Model-Based Systems Engineering
Mabrok, Mohamed
2017-01-09
In this paper, we introduce Category Theory as a formal foundation for model-based systems engineering. A generalised view of the system based on category theory is presented, where any system can be considered as a category. The objects of the category represent all the elements and components of the system and the arrows represent the relations between these components (objects). The relationship between these objects are the arrows or the morphisms in the category. The Olog is introduced as a formal language to describe a given real-world situation description and requirement writing. A simple example is provided.
Opinions of Secondary School Mathematics Teachers on Mathematical Modelling
Tutak, Tayfun; Güder, Yunus
2013-01-01
The aim of this study is to identify the opinions of secondary school mathematics teachers about mathematical modelling. Qualitative research was used. The participants of the study were 40 secondary school teachers working in the Bingöl Province in Turkey during 2012-2013 education year. Semi-structured interview form prepared by the researcher…
Mathematical Modeling and Simulation of SWRO Process Based on Simultaneous Method
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Aipeng Jiang
2014-01-01
Full Text Available Reverse osmosis (RO technique is one of the most efficient ways for seawater desalination to solve the shortage of freshwater. For prediction and analysis of the performance of seawater reverse osmosis (SWRO process, an accurate and detailed model based on the solution-diffusion and mass transfer theory is established. Since the accurate formulation of the model includes many differential equations and strong nonlinear equations (differential and algebraic equations, DAEs, to solve the problem efficiently, the simultaneous method through orthogonal collocation on finite elements and large scale solver were used to obtain the solutions. The model was fully discretized into NLP (nonlinear programming with large scale variables and equations, and then the NLP was solved by large scale solver of IPOPT. Validation of the formulated model and solution method is verified by case study on a SWRO plant. Then simulation and analysis are carried out to demonstrate the performance of reverse osmosis process; operational conditions such as feed pressure and feed flow rate as well as feed temperature are also analyzed. This work is of significant meaning for the detailed understanding of RO process and future energy saving through operational optimization.
Mathematical Modeling of a developed Central Receiver Based on Evacuated Solar Tubes
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Ali Basil. H.
2016-01-01
Full Text Available Solar central receiver plays a considerable role in the plant output power; it is one of the most important synthesis in the solar power tower plants. Its performance directly affects the efficiency of the entire solar power generation system. In this study, a new designed receiver model based on evacuated solar tube was proposed, and the dynamic characteristics of the developed receiver were investigated. In order to optimise and evaluate the dynamic characteristics of solar power plant components, the model investigates the solar radiation heat conversion process through the developed receiver, where the energy and mass conservation equations are used to determine the working fluid temperature and state through the receiver parts, beside the calculation and analysis of the thermal losses.
Mathematical models of granular matter
Mariano, Paolo; Giovine, Pasquale
2008-01-01
Granular matter displays a variety of peculiarities that distinguish it from other appearances studied in condensed matter physics and renders its overall mathematical modelling somewhat arduous. Prominent directions in the modelling granular flows are analyzed from various points of view. Foundational issues, numerical schemes and experimental results are discussed. The volume furnishes a rather complete overview of the current research trends in the mechanics of granular matter. Various chapters introduce the reader to different points of view and related techniques. New models describing granular bodies as complex bodies are presented. Results on the analysis of the inelastic Boltzmann equations are collected in different chapters. Gallavotti-Cohen symmetry is also discussed.
Zhang, Zili; Gao, Chao; Liu, Yuxin; Qian, Tao
2014-09-01
Ant colony optimization (ACO) algorithms often fall into the local optimal solution and have lower search efficiency for solving the travelling salesman problem (TSP). According to these shortcomings, this paper proposes a universal optimization strategy for updating the pheromone matrix in the ACO algorithms. The new optimization strategy takes advantages of the unique feature of critical paths reserved in the process of evolving adaptive networks of the Physarum-inspired mathematical model (PMM). The optimized algorithms, denoted as PMACO algorithms, can enhance the amount of pheromone in the critical paths and promote the exploitation of the optimal solution. Experimental results in synthetic and real networks show that the PMACO algorithms are more efficient and robust than the traditional ACO algorithms, which are adaptable to solve the TSP with single or multiple objectives. Meanwhile, we further analyse the influence of parameters on the performance of the PMACO algorithms. Based on these analyses, the best values of these parameters are worked out for the TSP.
Continuum mechanics the birthplace of mathematical models
Allen, Myron B
2015-01-01
Continuum mechanics is a standard course in many graduate programs in engineering and applied mathematics as it provides the foundations for the various differential equations and mathematical models that are encountered in fluid mechanics, solid mechanics, and heat transfer. This book successfully makes the topic more accessible to advanced undergraduate mathematics majors by aligning the mathematical notation and language with related courses in multivariable calculus, linear algebra, and differential equations; making connections with other areas of applied mathematics where parial differe
Mathematical modeling of laser lipolysis
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Reynaud Jean
2008-02-01
Full Text Available Abstract Background and Objectives Liposuction continues to be one of the most popular procedures performed in cosmetic surgery. As the public's demand for body contouring continues, laser lipolysis has been proposed to improve results, minimize risk, optimize patient comfort, and reduce the recovery period. Mathematical modeling of laser lipolysis could provide a better understanding of the laser lipolysis process and could determine the optimal dosage as a function of fat volume to be removed. Study design/Materials and Methods An Optical-Thermal-Damage Model was formulated using finite-element modeling software (Femlab 3.1, Comsol Inc. The general model simulated light distribution using the diffusion approximation of the transport theory, temperature rise using the bioheat equation and laser-induced injury using the Arrhenius damage model. Biological tissue was represented by two homogenous regions (dermis and fat layer with a nonlinear air-tissue boundary condition including free convection. Video recordings were used to gain a better understanding of the back and forth movement of the cannula during laser lipolysis in order to consider them in our mathematical model. Infrared video recordings were also performed in order to compare the actual surface temperatures to our calculations. The reduction in fat volume was determined as a function of the total applied energy and subsequently compared to clinical data reported in the literature. Results In patients, when using cooled tumescent anesthesia, 1064 nm Nd:YAG laser or 980 nm diode laser: (6 W, back and forth motion: 100 mm/s give similar skin surface temperature (max: 41°C. These measurements are in accordance with those obtained by mathematical modeling performed with a 1 mm cannula inserted inside the hypodermis layer at 0.8 cm below the surface. Similarly, the fat volume reduction observed in patients at 6-month follow up can be determined by mathematical modeling. This fat reduction
On religion and language evolutions seen through mathematical and agent based models
Ausloos, M
2011-01-01
(shortened version) Religions and languages are social variables, like age, sex, wealth or political opinions, to be studied like any other organizational parameter. In fact, religiosity is one of the most important sociological aspects of populations. Languages are also a characteristics of the human kind. New religions, new languages appear though others disappear. All religions and languages evolve when they adapt to the society developments. On the other hand, the number of adherents of a given religion, the number of persons speaking a language is not fixed. Several questions can be raised. E.g. from a macroscopic point of view : How many religions/languages exist at a given time? What is their distribution? What is their life time? How do they evolve?. From a microscopic view point: can one invent agent based models to describe macroscopic aspects? Does it exist simple evolution equations? It is intuitively accepted, but also found through from statistical analysis of the frequency distribution that an ...
Mathematical Model For Autoclave Curing Of Unsaturated Polyester Based Composite Materials
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Adnan A. Abdul Razak
2013-05-01
Full Text Available Heat transfer process involved in the autoclave curing of fiber-reinforced thermosetting composites is investigated numerically. A model for the prediction of the temperature and the extent of the reaction across the laminate thickness during curing process in the autoclave of unsaturated polyester based composite has been developed. The governing equation for one dimensional heat transfer, and accounting for the heat generation due to the exothermic cure reaction in the composites had been used. It was found that the temperature at the central of the laminate increases up to the external imposed temperature, because of the thermal conductivity of the resin and fiber. The heat generated by the exothermic reaction of the resin is not adequately removed; the increase in the temperature at the center increases the resins rate reaction, which in turn generates more heat.
Structured Mathematical Modeling of Industrial Boiler
Abdullah Nur Aziz; Yul Yunazwin Nazaruddin; Parsaulian Siregar; Yazid Bindar
2014-01-01
As a major utility system in industry, boilers consume a large portion of the total energy and costs. Significant reduction of boiler cost operation can be gained through improvements in efficiency. In accomplishing such a goal, an adequate dynamic model that comprehensively reflects boiler characteristics is required. This paper outlines the idea of developing a mathematical model of a water-tube industrial boiler based on first principles guided by the bond graph method in its derivation. T...
Energy Technology Data Exchange (ETDEWEB)
Rabi, Jose A. [Pontificia Univ. Catolica de Minas Gerais, Pocos de Caldas, MG (Brazil). Faculdade de Engenharia Civil]. E-mail: jrabi@pucpcaldas.br; Mohamad, Abdulmajeed A. [The University of Calgary, Alberta (Canada). Faculty of Engineering. Dept. of Mechanical and Manufacturing Engineering]. E-mail: amohamad@enme.ucalgary.ca
2004-07-01
Radon-222 is a radionuclide exhaled from phosphogypsum by-produced at phosphate fertilizer industries. Alternative large-scale application of this waste may indicate a material substitute for civil engineering provided that environmental issues concerning its disposal and management are overcome. The first part of this paper outlines a steady-state two-dimensional model for {sup 222}Rn transport through porous media, inside which emanation (source term) and decay (sink term) exist. Boussinesq approach is evoked for the laminar buoyancy-driven interstitial air flow, which is also modeled according to Darcy-Brinkman formulation. In order to account for simultaneous effects of entailed physical parameters, governing equations are cast into dimensionless form. Apart from usual controlling parameters like Reynolds, Prandtl, Schmidt, Grashof and Darcy numbers, three unconventional dimensionless groups are put forward. Having in mind {sup 222}Rn transport in phosphogypsum-bearing porous media, the physical meaning of those newly introduced parameters and representative values for the involved physical parameters are presented. A limiting diffusion-dominated scenario is addressed, for which an analytical solution is deduced for boundary conditions including an impermeable phosphogypsum stack base and a non-zero fixed concentration activity at the stack top. Accordingly, an expression for the average Sherwood number corresponding to the normalized {sup 222}Rn exhalation rate is presented.
A mathematical model of inheritance
Institute of Scientific and Technical Information of China (English)
瞿裕忠; 王志坚; 徐家福
1996-01-01
Inheritance is regarded as the hallmark of object-oriented programming languages.A mathematical model of inheritance is presented.In this model,the graph-sorted signature is introduced to represent the algebraic structure of the program,and an extension function on the graph-sorted signatures is used to formally describe the semantics of inheritance.The program’s algebraic structure reflects the syntactic constraints of the language and the corresponding extension function exposes the character of the language’s inheritance.
Mathematical Modeling in Combustion Science
Takeno, Tadao
1988-01-01
An important new area of current research in combustion science is reviewed in the contributions to this volume. The complicated phenomena of combustion, such as chemical reactions, heat and mass transfer, and gaseous flows, have so far been studied predominantly by experiment and by phenomenological approaches. But asymptotic analysis and other recent developments are rapidly changing this situation. The contributions in this volume are devoted to mathematical modeling in three areas: high Mach number combustion, complex chemistry and physics, and flame modeling in small scale turbulent flow combustion.
A Mathematical Model for Suppression Subtractive Hybridization
2002-01-01
Suppression subtractive hybridization (SSH) is frequently used to unearth differentially expressed genes on a whole-genome scale. Its versatility is based on combining cDNA library subtraction and normalization, which allows the isolation of sequences of varying degrees of abundance and differential expression. SSH is a complex process with many adjustable parameters that affect the outcome of gene isolation.We present a mathematical model of SSH based on DNA hybridization kinetics for assess...
Mathematical models for therapeutic approaches to control HIV disease transmission
Roy, Priti Kumar
2015-01-01
The book discusses different therapeutic approaches based on different mathematical models to control the HIV/AIDS disease transmission. It uses clinical data, collected from different cited sources, to formulate the deterministic as well as stochastic mathematical models of HIV/AIDS. It provides complementary approaches, from deterministic and stochastic points of view, to optimal control strategy with perfect drug adherence and also tries to seek viewpoints of the same issue from different angles with various mathematical models to computer simulations. The book presents essential methods and techniques for students who are interested in designing epidemiological models on HIV/AIDS. It also guides research scientists, working in the periphery of mathematical modeling, and helps them to explore a hypothetical method by examining its consequences in the form of a mathematical modelling and making some scientific predictions. The model equations, mathematical analysis and several numerical simulations that are...
A Mathematical Model of Mechanotransduction
Roth, Bradley J
2016-01-01
This article reviews the mechanical bidomain model, a mathematical description how the extracellular matrix and intracellular cytoskeleton are coupled by integrin proteins. The fundamental hypothesis is that differences between intracellular and extracellular displacements drive mechanotransduction. A one-dimensional example illustrates the model, which is then extended to two dimensions. In several cases the equations are solved analytically, illustrating how displacements divide into two parts: monodomain displacements are identical in both spaces and therefore do not contribute to mechanotransduction, whereas bidomain displacements cause mechanotransduction. A new length constant depends on the intracellular and extracellular shear moduli and the integrin spring constant, and bidomain effects often occur within a few length constants of the tissue edge. Numerical methods for solving the model equations are being developed. Precursors to the model and potential applications are discussed. The bidomain model...
Inquiry-Based Mathematics Curriculum Design for Young Children-Teaching Experiment and Reflection
Wu, Su-Chiao; Lin, Fou-Lai
2016-01-01
A group of teacher educators and practitioners in mathematics education and early childhood education generalized a set of inquiry-based mathematics models for Taiwanese young children of ages 3-6 and designed a series of inquiry-based mathematics curriculum tasks in cultivate the children's diverse mathematical concepts and mathematical power. In…
Models of Non-Life Insurance Mathematics
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Constanta Nicoleta BODEA
2008-01-01
Full Text Available In this communication we will discuss two regression credibility models from Non Ã¢Â€Â“ Life Insurance Mathematics that can be solved by means of matrix theory. In the first regression credibility model, starting from a well-known representation formula of the inverse for a special class of matrices a risk premium will be calculated for a contract with risk parameter q. In the next regression credibility model, we will obtain a credibility solution in the form of a linear combination of the individual estimate (based on the data of a particular state and the collective estimate (based on aggregate USA data. Mathematics Subject Classification: 62P05.
Identification of the noise using mathematical modelling
Dobeš, Josef; Kozubková, Milada; Mahdal, Miroslav
2016-03-01
In engineering applications the noisiness of a component or the whole device is a common problem. Currently, a lot of effort is put to eliminate noise of the already produced devices, to prevent generation of acoustic waves during the design of new components, or to specify the operating problems based on noisiness change. The experimental method and the mathematical modelling method belong to these identification methods. With the power of today's computers the ability to identify the sources of the noise on the mathematical modelling level is a very appreciated tool for engineers. For example, the noise itself may be generated by the vibration of the solid object, combustion, shock, fluid flow around an object or cavitation at the fluid flow in an object. For the given task generating the noise using fluid flow on the selected geometry and propagation of the acoustic waves and their subsequent identification are solved and evaluated. In this paper the principle of measurement of variables describing the fluid flow field and acoustic field are described. For the solution of fluid flow a mathematical model implemented into the CFD code is used. The mathematical modelling evaluation of the flow field is compared to the experimental data.
Mathematical Modelling Plant Signalling Networks
Muraro, D.
2013-01-01
During the last two decades, molecular genetic studies and the completion of the sequencing of the Arabidopsis thaliana genome have increased knowledge of hormonal regulation in plants. These signal transduction pathways act in concert through gene regulatory and signalling networks whose main components have begun to be elucidated. Our understanding of the resulting cellular processes is hindered by the complex, and sometimes counter-intuitive, dynamics of the networks, which may be interconnected through feedback controls and cross-regulation. Mathematical modelling provides a valuable tool to investigate such dynamics and to perform in silico experiments that may not be easily carried out in a laboratory. In this article, we firstly review general methods for modelling gene and signalling networks and their application in plants. We then describe specific models of hormonal perception and cross-talk in plants. This mathematical analysis of sub-cellular molecular mechanisms paves the way for more comprehensive modelling studies of hormonal transport and signalling in a multi-scale setting. © EDP Sciences, 2013.
Structured Mathematical Modeling of Industrial Boiler
Directory of Open Access Journals (Sweden)
Abdullah Nur Aziz
2014-04-01
Full Text Available As a major utility system in industry, boilers consume a large portion of the total energy and costs. Significant reduction of boiler cost operation can be gained through improvements in efficiency. In accomplishing such a goal, an adequate dynamic model that comprehensively reflects boiler characteristics is required. This paper outlines the idea of developing a mathematical model of a water-tube industrial boiler based on first principles guided by the bond graph method in its derivation. The model describes the temperature dynamics of the boiler subsystems such as economizer, steam drum, desuperheater, and superheater. The mathematical model was examined using industrial boiler performance test data.It can be used to build a boiler simulator or help operators run a boiler effectively.
A mathematical model of a computational problem solving system
Aris, Teh Noranis Mohd; Nazeer, Shahrin Azuan
2015-05-01
This paper presents a mathematical model based on fuzzy logic for a computational problem solving system. The fuzzy logic uses truth degrees as a mathematical model to represent vague algorithm. The fuzzy logic mathematical model consists of fuzzy solution and fuzzy optimization modules. The algorithm is evaluated based on a software metrics calculation that produces the fuzzy set membership. The fuzzy solution mathematical model is integrated in the fuzzy inference engine that predicts various solutions to computational problems. The solution is extracted from a fuzzy rule base. Then, the solutions are evaluated based on a software metrics calculation that produces the level of fuzzy set membership. The fuzzy optimization mathematical model is integrated in the recommendation generation engine that generate the optimize solution.
Paterson, Judy; Sneddon, Jamie
2011-01-01
This article reports on the learning conversations between a mathematician and a mathematics educator as they worked together to change the delivery model of a third year discrete mathematics course from a traditional lecture mode to team-based learning (TBL). This change prompted the mathematician to create team tasks which increasingly focused…
Teaching Mathematical Modelling for Earth Sciences via Case Studies
Yang, Xin-She
2010-05-01
Mathematical modelling is becoming crucially important for earth sciences because the modelling of complex systems such as geological, geophysical and environmental processes requires mathematical analysis, numerical methods and computer programming. However, a substantial fraction of earth science undergraduates and graduates may not have sufficient skills in mathematical modelling, which is due to either limited mathematical training or lack of appropriate mathematical textbooks for self-study. In this paper, we described a detailed case-study-based approach for teaching mathematical modelling. We illustrate how essential mathematical skills can be developed for students with limited training in secondary mathematics so that they are confident in dealing with real-world mathematical modelling at university level. We have chosen various topics such as Airy isostasy, greenhouse effect, sedimentation and Stokes' flow,free-air and Bouguer gravity, Brownian motion, rain-drop dynamics, impact cratering, heat conduction and cooling of the lithosphere as case studies; and we use these step-by-step case studies to teach exponentials, logarithms, spherical geometry, basic calculus, complex numbers, Fourier transforms, ordinary differential equations, vectors and matrix algebra, partial differential equations, geostatistics and basic numeric methods. Implications for teaching university mathematics for earth scientists for tomorrow's classroom will also be discussed. Refereces 1) D. L. Turcotte and G. Schubert, Geodynamics, 2nd Edition, Cambridge University Press, (2002). 2) X. S. Yang, Introductory Mathematics for Earth Scientists, Dunedin Academic Press, (2009).
Mathematical modeling of microbial growth in milk
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Jhony Tiago Teleken
2011-12-01
Full Text Available A mathematical model to predict microbial growth in milk was developed and analyzed. The model consists of a system of two differential equations of first order. The equations are based on physical hypotheses of population growth. The model was applied to five different sets of data of microbial growth in dairy products selected from Combase, which is the most important database in the area with thousands of datasets from around the world, and the results showed a good fit. In addition, the model provides equations for the evaluation of the maximum specific growth rate and the duration of the lag phase which may provide useful information about microbial growth.
Electrorheological fluids modeling and mathematical theory
Růžička, Michael
2000-01-01
This is the first book to present a model, based on rational mechanics of electrorheological fluids, that takes into account the complex interactions between the electromagnetic fields and the moving liquid. Several constitutive relations for the Cauchy stress tensor are discussed. The main part of the book is devoted to a mathematical investigation of a model possessing shear-dependent viscosities, proving the existence and uniqueness of weak and strong solutions for the steady and the unsteady case. The PDS systems investigated possess so-called non-standard growth conditions. Existence results for elliptic systems with non-standard growth conditions and with a nontrivial nonlinear r.h.s. and the first ever results for parabolic systems with a non-standard growth conditions are given for the first time. Written for advanced graduate students, as well as for researchers in the field, the discussion of both the modeling and the mathematics is self-contained.
Directory of Open Access Journals (Sweden)
Olga A. Iarmonova
2013-01-01
Full Text Available A fast mathematical model simulation module based on LabVIEW graphical programming environment has been developed. The module will be used for gas turbine and electrical power system co-simulation, and for testing automation of gas turbine automatic control systems.
Mathematical models in biological discovery
Walter, Charles
1977-01-01
When I was asked to help organize an American Association for the Advancement of Science symposium about how mathematical models have con tributed to biology, I agreed immediately. The subject is of immense importance and wide-spread interest. However, too often it is discussed in biologically sterile environments by "mutual admiration society" groups of "theoreticians", many of whom have never seen, and most of whom have never done, an original scientific experiment with the biolog ical materials they attempt to describe in abstract (and often prejudiced) terms. The opportunity to address the topic during an annual meeting of the AAAS was irresistable. In order to try to maintain the integrity ;,f the original intent of the symposium, it was entitled, "Contributions of Mathematical Models to Biological Discovery". This symposium was organized by Daniel Solomon and myself, held during the 141st annual meeting of the AAAS in New York during January, 1975, sponsored by sections G and N (Biological and Medic...
Mathematical Modelling Research in Turkey: A Content Analysis Study
Çelik, H. Coskun
2017-01-01
The aim of the present study was to examine the mathematical modelling studies done between 2004 and 2015 in Turkey and to reveal their tendencies. Forty-nine studies were selected using purposeful sampling based on the term, "mathematical modelling" with Higher Education Academic Search Engine. They were analyzed with content analysis.…
Naderinezhad, Samira; Etesami, Nasrin; Poormalek Najafabady, Arefe; Ghasemi Falavarjani, Majid
2016-01-01
The effect of air temperature, air velocity, and sample shapes (circle and square with the same cross-sectional area) on kinetic drying of potato slices in a tunnel dryer was investigated experimentally and a suitable drying model was developed. The experiments of drying of potato slices were conducted at an air temperature of 45-70°C with an air velocity 1.60 and 1.81 m sec(-1). Results showed that drying temperature was the most effective parameter in the drying rate. The influence of air velocity was more profound in low temperature. The time for drying square slices was lower compared to the circle ones. Furthermore, drying data were fitted to different empirical models. Among the models, Midilli-Kucuk was the best to explain the single layer drying of potato slices. The parameters of this model were determined as functions of air velocity and temperature by multiple regression analysis for circle and square slices. Various statistical parameters were examined for evaluating the model.
A mathematical description of a growing cell colony based on the mechanical bidomain model
Auddya, Debabrata; Roth, Bradley J.
2017-03-01
The mechanical bidomain model is used to describe a colony of cells growing on a substrate. Analytical expressions are derived for the intracellular and extracellular displacements. Mechanotransduction events are driven by the difference between the displacements in the two spaces, corresponding to the force acting on integrins. The equation for the displacement consists of two terms: one proportional to the radius that is the same in the intracellular and extracellular spaces (the monodomain term) and one that is proportional to a modified Bessel function that is responsible for mechanotransduction (the bidomain term). The model predicts that mechanotransduction occurs within a few length constants of the colony’s edge, and an expression for the length constant contains the intracellular and extracellular shear moduli and the spring constant of the integrins coupling the two spaces. The model predictions are qualitatively consistent with experiments on human embryonic stem cell colonies, in which differentiation is localized near the edge.
Mathematical modeling in biomedical imaging
2012-01-01
This volume reports on recent mathematical and computational advances in optical, ultrasound, and opto-acoustic tomographies. It outlines the state-of-the-art and future directions in these fields and provides readers with the most recently developed mathematical and computational tools. It is particularly suitable for researchers and graduate students in applied mathematics and biomedical engineering.
Directory of Open Access Journals (Sweden)
Liu Cong
2011-12-01
Full Text Available Abstract Background Elucidating the effects of drugs on solid tumours is a highly challenging multi-level problem, since this involves many complexities associated with transport and cellular response, which in turn is characterized by highly non-linear chemical signal transduction. Appropriate systems frameworks are needed to seriously address the sources of these complexities, especially from the cellular side. Results We develop a skeletal modelling framework incorporating interstitial drug transport, intracellular signal processing and cell population descriptions. The descriptions aim to appropriately capture the nature of information flow. The model is deliberately formulated to start with simple intracellular descriptions so that additional features can be incorporated in a modular fashion. Two kinds of intracellular signalling modules which describe the drug effect were considered, one a monostable switch and the other a bistable switch. Analysis of our model revealed how different drug stimuli can lead to cell killing in the tumour. Interestingly both modules considered exhibited similar trends. The effects of important parameters were also studied. Conclusions We have created a predictive systems platform integrating drug transport and cellular response which can be systematically augmented to include additional layers of cellular complexity. Our results indicate that intracellular signalling models which are qualitatively different can give rise to similar behaviour to simple (and typical stimuli, and that validating intracellular descriptions must be performed with care by considering a variety of drug stimuli.
Building fire zone model with symbolic mathematics
Institute of Scientific and Technical Information of China (English)
武红梅; 郜冶; 周允基
2009-01-01
To apply the fire modelling for the fire engineer with symbolic mathematics,the key equations of a zone model were demonstrated. There were thirteen variables with nine constraints,so only four ordinary differential equations (ODEs) were required to solve. A typical fire modelling with two-room structure was studied. Accordingly,the source terms included in the ODEs were simplified and modelled,and the fourth Runge-Kutta method was used to solve the ordinary differential equations (ODEs) with symbolic mathematics. Then a zone model could be used with symbolic mathematics. It is proposed that symbolic mathematics is possible for use by fire engineer.
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Maslov A. A.
2016-12-01
Full Text Available Definition of preparatory parameters for sterilization regime of canned "Natural Atlantic Mackerel with Oil" is the aim of current study. PRSC software developed at the department of automation and computer engineering is used for preparatory selection. To determine the parameters of process model, in laboratory autoclave AVK-30M the pre-trial process of sterilization and cooling in water with backpressure of canned "Natural Atlantic Mackerel with Oil" in can N 3 has been performed. Gathering information about the temperature in the autoclave sterilization chamber and the can with product has been carried out using Ellab TrackSense PRO loggers. Due to the obtained information three transfer functions for the product model have been identified: in the least heated area of autoclave, the average heated and the most heated. In PRSC programme temporary temperature dependences in the sterilization chamber have been built using this information. The model of sterilization process of canned "Natural Atlantic Mackerel with Oil" has been received after the pre-trial process. Then in the automatic mode the sterilization regime of canned "Natural Atlantic Mackerel with Oil" has been selected using the value of actual effect close to normative sterilizing effect (5.9 conditional minutes. Furthermore, in this study step-mode sterilization of canned "Natural Atlantic Mackerel with Oil" has been selected. Utilization of step-mode sterilization with the maximum temperature equal to 125 °C in the sterilization chamber allows reduce process duration by 10 %. However, the application of this regime in practice requires additional research. Using the described approach based on the developed mathematical models of the process allows receive optimal step and variable canned food sterilization regimes with high energy efficiency and product quality.
Mathematical modelling of leprosy and its control.
Blok, David J; de Vlas, Sake J; Fischer, Egil A J; Richardus, Jan Hendrik
2015-03-01
Leprosy or Hansen's disease is an infectious disease caused by the bacterium Mycobacterium leprae. The annual number of new leprosy cases registered worldwide has remained stable over the past years at over 200,000. Early case finding and multidrug therapy have not been able interrupt transmission completely. Elimination requires innovation in control and sustained commitment. Mathematical models can be used to predict the course of leprosy incidence and the effect of intervention strategies. Two compartmental models and one individual-based model have been described in the literature. Both compartmental models investigate the course of leprosy in populations and the long-term impact of control strategies. The individual-based model focusses on transmission within households and the impact of case finding among contacts of new leprosy patients. Major improvement of these models should result from a better understanding of individual differences in exposure to infection and developing leprosy after exposure. Most relevant are contact heterogeneity, heterogeneity in susceptibility and spatial heterogeneity. Furthermore, the existing models have only been applied to a limited number of countries. Parameterization of the models for other areas, in particular those with high incidence, is essential to support current initiatives for the global elimination of leprosy. Many challenges remain in understanding and dealing with leprosy. The support of mathematical models for understanding leprosy epidemiology and supporting policy decision making remains vital.
Brace, Robert A; Anderson, Debra F; Cheung, Cecilia Y
2014-11-15
Experimentation in late-gestation fetal sheep has suggested that regulation of amniotic fluid (AF) volume occurs primarily by modulating the rate of intramembranous transport of water and solutes across the amnion into underlying fetal blood vessels. In order to gain insight into intramembranous transport mechanisms, we developed a computer model that allows simulation of experimentally measured changes in AF volume and composition over time. The model included fetal urine excretion and lung liquid secretion as inflows into the amniotic compartment plus fetal swallowing and intramembranous absorption as outflows. By using experimental flows and solute concentrations for urine, lung liquid, and swallowed fluid in combination with the passive and active transport mechanisms of the intramembranous pathway, we simulated AF responses to basal conditions, intra-amniotic fluid infusions, fetal intravascular infusions, urine replacement, and tracheoesophageal occlusion. The experimental data are consistent with four intramembranous transport mechanisms acting in concert: 1) an active unidirectional bulk transport of AF with all dissolved solutes out of AF into fetal blood presumably by vesicles; 2) passive bidirectional diffusion of solutes, such as sodium and chloride, between fetal blood and AF; 3) passive bidirectional water movement between AF and fetal blood; and 4) unidirectional transport of lactate into the AF. Further, only unidirectional bulk transport is dynamically regulated. The simulations also identified areas for future study: 1) identifying intramembranous stimulators and inhibitors, 2) determining the semipermeability characteristics of the intramembranous pathway, and 3) characterizing the vesicles that are the primary mediators of intramembranous transport.
Mathematical models of human behavior
DEFF Research Database (Denmark)
Møllgaard, Anders Edsberg
During the last 15 years there has been an explosion in human behavioral data caused by the emergence of cheap electronics and online platforms. This has spawned a whole new research field called computational social science, which has a quantitative approach to the study of human behavior. Most...... studies have considered data sets with just one behavioral variable such as email communication. The Social Fabric interdisciplinary research project is an attempt to collect a more complete data set on human behavior by providing 1000 smartphones with pre-installed data collection software to students...... data set, along with work on other behavioral data. The overall goal is to contribute to a quantitative understanding of human behavior using big data and mathematical models. Central to the thesis is the determination of the predictability of different human activities. Upper limits are derived...
Suzuki, Shozo; Sato, Tasuku; Maeda, Akinobu; Takahashi, Yasuo
2006-02-01
We investigated the effects of program design on 400-m sprint time by applying a Rating of Perceived Exertion (RPE) mathematical model to training performance. The subject was 24 years old and had been training for 9 years. His best performance in 400-m sprint competitions was 45.50 seconds. Body weight, resting heart rate, training time and RPE were monitored daily after training sessions. Similarly, performance in 400-m races was recorded 9 times during 2003. At the World Championships in Athletics in France, the subject's team placed eighth in the 1,600-m relay. The RPE mathematical model was able to predict changes in performance. Rate of matching was statistically significant (r(2) = 0.83, F ratio = 34.27, p sprinter indicates a potentially powerful tool that can be applied to accurately assess the effects of training on athletic performance.
How parrots talk: insights based on CT scans, image processing, and mathematical models
Patterson, Dianne K.; Pepperberg, Irene M.; Story, Brad H.; Hoffman, Eric A.
1997-05-01
Little is known about mechanisms of speech production in parrots. Recently, however, techniques for correlating vocal tract shape with vowel production in humans have become more sophisticated and we have adapted these techniques for use with parrots. We scanned two grey parrot heads with intact vocal tracts. One specimen, 'Oldbird' was fixed with its beak propped open; the second 'Youngbird' was fixed with its beak closed. Using VIDA software, we (1) established that differences in tongue and larynx positioning resulted from opening or closing the beak; and (2) obtained lengths and area functions for the trachea, glottis, pharynx, mouth, and choana for both specimens and esophageal length and area functions for the first specimen. We entered lengths and area functions into a 1D wave propagation model to determine the natural formant frequencies associated with an open versus closed beak. We also determined how manipulating lengths and area functions could affect formant frequency and relative intensity. Finally, by comparing observed grey parrot vowel formant, we predict how the parrot uses its vocal tract to produce speech.
Computacional-representantional model of mathematics (crmmath)
Toro Carvajal, Luis Alberto
2016-01-01
This paper presents the so-called computational representational model of mathematics (MCRMATH), its theoretical importance for mathematics education and its relation with the use of technology tools in mathematics teaching. To do this, from a cognitive point of view, we conduct a research study of representations and we explain the computational-representational model of mind (CRMM).
Mathematical modeling courses for Media technology students
DEFF Research Database (Denmark)
Timcenko, Olga
2009-01-01
This paper addresses curriculum development for Mathematical Modeling course at Medialogy education. Medialogy as a study line was established in 2002 at Faculty for Engineering and Natural Sciences at Aalborg University, and mathematics curriculum has already been revised three times, Mathematical...... Modeling on 6th semester being the latest addition. Some of the reasoning behind curriculum development, lessons learned and remaining issues are presented and discussed. ...
Mathematical modeling and visualization of functional neuroimages
DEFF Research Database (Denmark)
Rasmussen, Peter Mondrup
This dissertation presents research results regarding mathematical modeling in the context of the analysis of functional neuroimages. Specifically, the research focuses on pattern-based analysis methods that recently have become popular within the neuroimaging community. Such methods attempt...... to predict or decode experimentally defined cognitive states based on brain scans. The topics covered in the dissertation are divided into two broad parts: The first part investigates the relative importance of model selection on the brain patterns extracted form analysis models. Typical neuroimaging data...... sets are characterized by relatively few data observations in a high dimensional space. The process of building models in such data sets often requires strong regularization. Often, the degree of model regularization is chosen in order to maximize prediction accuracy. We focus on the relative influence...
Dermol, Janja; Miklavčič, Damijan
2014-12-01
High voltage electric pulses cause electroporation of the cell membrane. Consequently, flow of the molecules across the membrane increases. In our study we investigated possibility to predict the percentage of the electroporated cells in an inhomogeneous electric field on the basis of the experimental results obtained when cells were exposed to a homogeneous electric field. We compared and evaluated different mathematical models previously suggested by other authors for interpolation of the results (symmetric sigmoid, asymmetric sigmoid, hyperbolic tangent and Gompertz curve). We investigated the density of the cells and observed that it has the most significant effect on the electroporation of the cells while all four of the mathematical models yielded similar results. We were able to predict electroporation of cells exposed to an inhomogeneous electric field based on mathematical modeling and using mathematical formulations of electroporation probability obtained experimentally using exposure to the homogeneous field of the same density of cells. Models describing cell electroporation probability can be useful for development and presentation of treatment planning for electrochemotherapy and non-thermal irreversible electroporation.
Mathematical Modelling as a Professional Task
Frejd, Peter; Bergsten, Christer
2016-01-01
Educational research literature on mathematical modelling is extensive. However, not much attention has been paid to empirical investigations of its scholarly knowledge from the perspective of didactic transposition processes. This paper reports from an interview study of mathematical modelling activities involving nine professional model…
Mathematical Modeling of the Agriculture Crop Technology
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D. Drucioc
1999-02-01
Full Text Available The organized structure of computer system for economic and ecological estimation of agriculture crop technologies is described. The system is composed of six interconnected blocks. The linear, non-linear and stochastic mathematical models for machinery sizing and selection in farm-level cropping system is presented in the mathematical model block of computer system.
Mathematical modelling of scour: A review
DEFF Research Database (Denmark)
Sumer, B. Mutlu
2007-01-01
A review is presented of mathematical modelling of scour around hydraulic and marine structures. Principal ideas, general features and procedures are given. The paper is organized in three sections: the first two sections deal with the mathematical modelling of scour around piers/piles and pipeli......A review is presented of mathematical modelling of scour around hydraulic and marine structures. Principal ideas, general features and procedures are given. The paper is organized in three sections: the first two sections deal with the mathematical modelling of scour around piers....../piles and pipelines, respectively, the two benchmark cases, while the third section deals with the mathematical modelling of scour around other structures such as groins, breakwaters and sea walls. A section is also added to discuss potential future research areas. Over one hundred references are included...
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Chinyere Nwabugwu
2013-01-01
Full Text Available The dependence on the overexpression of a single oncogene constitutes an exploitable weakness for molecular targeted therapy. These drugs can produce dramatic tumor regression by targeting the driving oncogene, but relapse often follows. Understanding the complex interactions of the tumor’s multifaceted response to oncogene inactivation is key to tumor regression. It has become clear that a collection of cellular responses lead to regression and that immune-mediated steps are vital to preventing relapse. Our integrative mathematical model includes a variety of cellular response mechanisms of tumors to oncogene inactivation. It allows for correct predictions of the time course of events following oncogene inactivation and their impact on tumor burden. A number of aspects of our mathematical model have proven to be necessary for recapitulating our experimental results. These include a number of heterogeneous tumor cell states since cells following different cellular programs have vastly different fates. Stochastic transitions between these states are necessary to capture the effect of escape from oncogene addiction (i.e., resistance. Finally, delay differential equations were used to accurately model the tumor growth kinetics that we have observed. We use this to model oncogene addiction in MYC-induced lymphoma, osteosarcoma, and hepatocellular carcinoma.
Methods and models in mathematical biology deterministic and stochastic approaches
Müller, Johannes
2015-01-01
This book developed from classes in mathematical biology taught by the authors over several years at the Technische Universität München. The main themes are modeling principles, mathematical principles for the analysis of these models, and model-based analysis of data. The key topics of modern biomathematics are covered: ecology, epidemiology, biochemistry, regulatory networks, neuronal networks, and population genetics. A variety of mathematical methods are introduced, ranging from ordinary and partial differential equations to stochastic graph theory and branching processes. A special emphasis is placed on the interplay between stochastic and deterministic models.
A Seminar in Mathematical Model-Building.
Smith, David A.
1979-01-01
A course in mathematical model-building is described. Suggested modeling projects include: urban problems, biology and ecology, economics, psychology, games and gaming, cosmology, medicine, history, computer science, energy, and music. (MK)
Applications of mathematical models of road cycling
Dahmen, Thorsten; Saupe, Dietmar; Wolf, Stefan
2012-01-01
This contribution discusses several use cases of mathematical models for road cycling. A mechanical model for the pedaling forces is the basis for an accurate indoor ergometer simulation of road cycling on real-world tracks. Together with a simple physiological model for the exertion of the athlete as a function of his/her accumulated power output, an optimal riding strategy for time trials on mountain ascents is computed. A combination of the two models leads to a mathematical optimization p...
The mathematics of cancer: integrating quantitative models.
Altrock, Philipp M; Liu, Lin L; Michor, Franziska
2015-12-01
Mathematical modelling approaches have become increasingly abundant in cancer research. The complexity of cancer is well suited to quantitative approaches as it provides challenges and opportunities for new developments. In turn, mathematical modelling contributes to cancer research by helping to elucidate mechanisms and by providing quantitative predictions that can be validated. The recent expansion of quantitative models addresses many questions regarding tumour initiation, progression and metastases as well as intra-tumour heterogeneity, treatment responses and resistance. Mathematical models can complement experimental and clinical studies, but also challenge current paradigms, redefine our understanding of mechanisms driving tumorigenesis and shape future research in cancer biology.
Mathematical Modelling for Micropiles Embedded in Salt Rock
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Rădan (Toader Georgiana
2016-03-01
Full Text Available This study presents the results of the mathematical modelling for the micropiles foundation of an investement objective located in Slanic, Prahova county. Three computing models were created and analyzed with software, based on Finite Element Method. With Plaxis 2D model was analyzed the isolated micropile and the three-dimensional analysis was made with Plaxis 3D model, for group of micropiles. For the micropiles foundation was used Midas GTS-NX model. The mathematical models were calibrated based with the in-situ tests results for axially loaded micropiles, embedded in salt rock. The paper presents the results obtained with the three software, the calibration and validation models.
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Farkas Csilla
2016-09-01
Full Text Available Knowledge of hydrological processes and water balance elements are important for climate adaptive water management as well as for introducing mitigation measures aiming to improve surface water quality. Mathematical models have the potential to estimate changes in hydrological processes under changing climatic or land use conditions. These models, indeed, need careful calibration and testing before being applied in decision making. The aim of this study was to compare the capability of five different hydrological models to predict the runoff and the soil water balance elements of a small catchment in Norway. The models were harmonised and calibrated against the same data set. In overall, a good agreement between the measured and simulated runoff was obtained for the different models when integrating the results over a week or longer periods. Model simulations indicate that forest appears to be very important for the water balance in the catchment, and that there is a lack of information on land use specific water balance elements. We concluded that joint application of hydrological models serves as a good background for ensemble modelling of water transport processes within a catchment and can highlight the uncertainty of models forecast.
Computer-Game-Based Tutoring of Mathematics
Ke, Fengfeng
2013-01-01
This in-situ, descriptive case study examined the potential of implementing computer mathematics games as an anchor for tutoring of mathematics. Data were collected from middle school students at a rural pueblo school and an urban Hispanic-serving school, through in-field observation, content analysis of game-based tutoring-learning interactions,…
The mathematical bases for qualitative reasoning
Kalagnanam, Jayant; Simon, Herbert A.; Iwasaki, Yumi
1991-01-01
The practices of researchers in many fields who use qualitative reasoning are summarized and explained. The goal is to gain an understanding of the formal assumptions and mechanisms that underlie this kind of analysis. The explanations given are based on standard mathematical formalisms, particularly on ordinal properties, continuous differentiable functions, and the mathematics of nonlinear dynamic systems.
Mathematical modeling and computational intelligence in engineering applications
Silva Neto, Antônio José da; Silva, Geraldo Nunes
2016-01-01
This book brings together a rich selection of studies in mathematical modeling and computational intelligence, with application in several fields of engineering, like automation, biomedical, chemical, civil, electrical, electronic, geophysical and mechanical engineering, on a multidisciplinary approach. Authors from five countries and 16 different research centers contribute with their expertise in both the fundamentals and real problems applications based upon their strong background on modeling and computational intelligence. The reader will find a wide variety of applications, mathematical and computational tools and original results, all presented with rigorous mathematical procedures. This work is intended for use in graduate courses of engineering, applied mathematics and applied computation where tools as mathematical and computational modeling, numerical methods and computational intelligence are applied to the solution of real problems.
Study of Photovoltaic Cells Engineering Mathematical Model
Zhou, Jun; Yu, Zhengping; Lu, Zhengyi; Li, Chenhui; Zhang, Ruilan
2016-11-01
The characteristic curve of photovoltaic cells is the theoretical basis of PV Power, which simplifies the existing mathematical model, eventually, obtains a mathematical model used in engineering. The characteristic curve of photovoltaic cells contains both exponential and logarithmic calculation. The exponential and logarithmic spread out through Taylor series, which includes only four arithmetic and use single chip microcontroller as the control center. The result shows that: the use of single chip microcontroller for calculating exponential and logarithmic functions, simplifies mathematical model of PV curve, also can meet the specific conditions’ requirement for engineering applications.
Mathematical modeling a chemical engineer's perspective
Rutherford, Aris
1999-01-01
Mathematical modeling is the art and craft of building a system of equations that is both sufficiently complex to do justice to physical reality and sufficiently simple to give real insight into the situation. Mathematical Modeling: A Chemical Engineer's Perspective provides an elementary introduction to the craft by one of the century's most distinguished practitioners.Though the book is written from a chemical engineering viewpoint, the principles and pitfalls are common to all mathematical modeling of physical systems. Seventeen of the author's frequently cited papers are reprinted to illus
Corey, Katelyn C.
2016-01-01
Using a mathematical model with realistic demography, we analyze a large outbreak of measles in Muyinga sector in rural Burundi in 1988–1989. We generate simulated epidemic curves and age × time epidemic surfaces, which we qualitatively and quantitatively compare with the data. Our findings suggest that supplementary immunization activities (SIAs) should be used in places where routine vaccination cannot keep up with the increasing numbers of susceptible individuals resulting from population growth or from logistical problems such as cold chain maintenance. We use the model to characterize the relationship between SIA frequency and SIA age range necessary to suppress measles outbreaks. If SIAs are less frequent, they must expand their target age range. PMID:27672515
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Katelyn C. Corey
2016-09-01
Full Text Available Using a mathematical model with realistic demography, we analyze a large outbreak of measles in Muyinga sector in rural Burundi in 1988–1989. We generate simulated epidemic curves and age × time epidemic surfaces, which we qualitatively and quantitatively compare with the data. Our findings suggest that supplementary immunization activities (SIAs should be used in places where routine vaccination cannot keep up with the increasing numbers of susceptible individuals resulting from population growth or from logistical problems such as cold chain maintenance. We use the model to characterize the relationship between SIA frequency and SIA age range necessary to suppress measles outbreaks. If SIAs are less frequent, they must expand their target age range.
Fortenbaugh, R. L.
1980-01-01
Equations incorporated in a VATOL six degree of freedom off-line digital simulation program and data for the Vought SF-121 VATOL aircraft concept which served as the baseline for the development of this program are presented. The equations and data are intended to facilitate the development of a piloted VATOL simulation. The equation presentation format is to state the equations which define a particular model segment. Listings of constants required to quantify the model segment, input variables required to exercise the model segment, and output variables required by other model segments are included. In several instances a series of input or output variables are followed by a section number in parentheses which identifies the model segment of origination or termination of those variables.
Institute of Scientific and Technical Information of China (English)
陈宇; 臧美英; 李林辉
2015-01-01
Discrete Mathematics is the core courses of the computer and the related majors, This article describes the basic Discrete Mathematics, ACM and ACM on-line evaluation system ,in addition ,it puts Discrete Mathematics practice teaching reform measures based on ACM model ,it explores the ways and means of teaching and reforms the experimental teaching .This reformation will improve the teaching quality and teaching level of the Discrete Mathematics ,it can help to cultivate students' abstract thinking ,logical thinking ,psychological quality and team cooperation ability.%离散数学是计算机及相关专业核心课程,本文在介绍离散数学、ACM及ACM在线评测系统的基础上,提出了基于ACM模式的离散数学实验探究,探讨了教学方式与手段及实验教学的改革.这种改革将提高离散数学课程的教学质量和教学水平,有助于培养学生的抽象思维、逻辑思维、心理素质及团队协作能力.
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Jie Liang
2017-03-01
Full Text Available Electricity demand forecasting can provide the scientific basis for the country to formulate the power industry development strategy and the power-generating target, which further promotes the sustainable, healthy and rapid development of the national economy. In this paper, a new mathematical hybrid method is proposed to forecast electricity demand. In line with electricity demand feature, the framework of joint-forecasting model is established and divided into two procedures: firstly, the modified GM(1,1 model and the Logistic model are used to make single forecasting. Then, the induced ordered weighted harmonic averaging operator (IOWHA is applied to combine these two single models and make joint-forecasting. Forecasting results demonstrate that this new hybrid model is superior to both single-forecasting approaches and traditional joint-forecasting methods, thus verifying the high prediction validity and accuracy of mentioned joint-forecasting model. Finally, detailed forecasting-outcomes on electricity demand of China in 2016–2020 are discussed and displayed a slow-growth smoothly over the next five years.
A mathematical model of aortic aneurysm formation
Hao, Wenrui; Gong, Shihua; Wu, Shuonan; Xu, Jinchao; Go, Michael R.; Friedman, Avner; Zhu, Dai
2017-01-01
Abdominal aortic aneurysm (AAA) is a localized enlargement of the abdominal aorta, such that the diameter exceeds 3 cm. The natural history of AAA is progressive growth leading to rupture, an event that carries up to 90% risk of mortality. Hence there is a need to predict the growth of the diameter of the aorta based on the diameter of a patient’s aneurysm at initial screening and aided by non-invasive biomarkers. IL-6 is overexpressed in AAA and was suggested as a prognostic marker for the risk in AAA. The present paper develops a mathematical model which relates the growth of the abdominal aorta to the serum concentration of IL-6. Given the initial diameter of the aorta and the serum concentration of IL-6, the model predicts the growth of the diameter at subsequent times. Such a prediction can provide guidance to how closely the patient’s abdominal aorta should be monitored. The mathematical model is represented by a system of partial differential equations taking place in the aortic wall, where the media is assumed to have the constituency of an hyperelastic material. PMID:28212412
Mathematical modeling in biomedical imaging
2009-01-01
This volume gives an introduction to a fascinating research area to applied mathematicians. It is devoted to providing the exposition of promising analytical and numerical techniques for solving challenging biomedical imaging problems, which trigger the investigation of interesting issues in various branches of mathematics.
Mathematical Modeling of Chemical Stoichiometry
Croteau, Joshua; Fox, William P.; Varazo, Kristofoland
2007-01-01
In beginning chemistry classes, students are taught a variety of techniques for balancing chemical equations. The most common method is inspection. This paper addresses using a system of linear mathematical equations to solve for the stoichiometric coefficients. Many linear algebra books carry the standard balancing of chemical equations as an…
Mathematical modeling of a V-stack piezoelectric aileron actuation
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Ioan URSU
2016-12-01
Full Text Available The article presents a mathematical modeling of aileron actuation that uses piezo V-shaped stacks. The aim of the actuation is the increasing of flutter speed in the context of a control law, in order to widen the flight envelope. In this way the main advantage of such a piezo actuator, the bandwidth is exploited. The mathematical model is obtained based on free body diagrams, and the numerical simulations allow a preliminary sizing of the actuator.
Applied mathematics: Models, Discretizations, and Solvers
Institute of Scientific and Technical Information of China (English)
D.E. Keyes
2007-01-01
@@ Computational plasma physicists inherit decades of developments in mathematical models, numerical algorithms, computer architecture, and software engineering, whose recent coming together marks the beginning of a new era of large-scale simulation.
Zeytun, Aysel Sen; Cetinkaya, Bulent; Erbas, Ayhan Kursat
2017-01-01
This paper investigates how prospective teachers develop mathematical models while they engage in modeling tasks. The study was conducted in an undergraduate elective course aiming to improve prospective teachers' mathematical modeling abilities, while enhancing their pedagogical knowledge for the integrating of modeling tasks into their future…
A practical course in differential equations and mathematical modeling
Ibragimov , Nail H
2009-01-01
A Practical Course in Differential Equations and Mathematical Modelling is a unique blend of the traditional methods of ordinary and partial differential equations with Lie group analysis enriched by the author's own theoretical developments. The book which aims to present new mathematical curricula based on symmetry and invariance principles is tailored to develop analytic skills and working knowledge in both classical and Lie's methods for solving linear and nonlinear equations. This approach helps to make courses in differential equations, mathematical modelling, distributions and fundame
Economic mathematical methods and forecasting models
K. Karpovska-Skoryk
2000-01-01
In the article the questions of the expert system, based on the fuzzy mathematics, are discussed. It is pointed out that usage of such a system for medical insurance in the conditions of the Ukrainian economy is very convenient.
Mathematical Modeling of Hybrid Electrical Engineering Systems
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A. A. Lobaty
2016-01-01
Full Text Available A large class of systems that have found application in various industries and households, electrified transportation facilities and energy sector has been classified as electrical engineering systems. Their characteristic feature is a combination of continuous and discontinuous modes of operation, which is reflected in the appearance of a relatively new term “hybrid systems”. A wide class of hybrid systems is pulsed DC converters operating in a pulse width modulation, which are non-linear systems with variable structure. Using various methods for linearization it is possible to obtain linear mathematical models that rather accurately simulate behavior of such systems. However, the presence in the mathematical models of exponential nonlinearities creates considerable difficulties in the implementation of digital hardware. The solution can be found while using an approximation of exponential functions by polynomials of the first order, that, however, violates the rigor accordance of the analytical model with characteristics of a real object. There are two practical approaches to synthesize algorithms for control of hybrid systems. The first approach is based on the representation of the whole system by a discrete model which is described by difference equations that makes it possible to synthesize discrete algorithms. The second approach is based on description of the system by differential equations. The equations describe synthesis of continuous algorithms and their further implementation in a digital computer included in the control loop system. The paper considers modeling of a hybrid electrical engineering system using differential equations. Neglecting the pulse duration, it has been proposed to describe behavior of vector components in phase coordinates of the hybrid system by stochastic differential equations containing generally non-linear differentiable random functions. A stochastic vector-matrix equation describing dynamics of the
Laser interaction with biological material mathematical modeling
Kulikov, Kirill
2014-01-01
This book covers the principles of laser interaction with biological cells and tissues of varying degrees of organization. The problems of biomedical diagnostics are considered. Scattering of laser irradiation of blood cells is modeled for biological structures (dermis, epidermis, vascular plexus). An analytic theory is provided which is based on solving the wave equation for the electromagnetic field. It allows the accurate analysis of interference effects arising from the partial superposition of scattered waves. Treated topics of mathematical modeling are: optical characterization of biological tissue with large-scale and small-scale inhomogeneities in the layers, heating blood vessel under laser irradiation incident on the outer surface of the skin and thermo-chemical denaturation of biological structures at the example of human skin.
Analysis of mathematical modelling on potentiometric biosensors.
Mehala, N; Rajendran, L
2014-01-01
A mathematical model of potentiometric enzyme electrodes for a nonsteady condition has been developed. The model is based on the system of two coupled nonlinear time-dependent reaction diffusion equations for Michaelis-Menten formalism that describes the concentrations of substrate and product within the enzymatic layer. Analytical expressions for the concentration of substrate and product and the corresponding flux response have been derived for all values of parameters using the new homotopy perturbation method. Furthermore, the complex inversion formula is employed in this work to solve the boundary value problem. The analytical solutions obtained allow a full description of the response curves for only two kinetic parameters (unsaturation/saturation parameter and reaction/diffusion parameter). Theoretical descriptions are given for the two limiting cases (zero and first order kinetics) and relatively simple approaches for general cases are presented. All the analytical results are compared with simulation results using Scilab/Matlab program. The numerical results agree with the appropriate theories.
The possibilities of a modelling perspective for school mathematics
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Dirk Wessels
2009-09-01
complex teaching methodology requires in-depth thinking about the role of the teacher, the role of the learner, the nature of the classroom culture, the nature of the negotiation of meaning between the teacher and individuals or groups, the nature of selected problems and material, as well as the kind of integrative assessment used in the mathematics classroom. Modelling is closely related to the problem-centred teaching approach, but it also smoothly relates to bigger and longer mathematical tasks. This article gives a theoretical exposition of the scope and depth of mathematical modelling. It is possible to introduce modelling at every school phase in our educational sytem. Modelling in school mathematics seems to make the learning of mathematics more effective. The mastering of problem solving and modelling strategies has deﬁnitely changed the orientation, the competencies and performances of learners at each school level. It would appear from research that learners like the application side of mathematics and that they want to see it in action. Genuine real life problems should be selected, which is why a modelling perspective is so important for the teaching and mastering of mathematics. Modelling should be integrated into the present curriculum because learners will then get full access to involvement in the classroom, to mathematisation, to doing problems, to criticising arguments, to ﬁnding proofs, to recognising concepts and to obtaining the ability to abstract these from the realistic situation. Modelling should be given a full opportunity in mathematics teacher education so that our learners can get the full beneﬁt of it. This will put the mathematical performances of learners in our country on a more solid base, which will make our learners more competitive at all levels in the future.
Mathematical biology modules based on modern molecular biology and modern discrete mathematics.
Robeva, Raina; Davies, Robin; Hodge, Terrell; Enyedi, Alexander
2010-01-01
We describe an ongoing collaborative curriculum materials development project between Sweet Briar College and Western Michigan University, with support from the National Science Foundation. We present a collection of modules under development that can be used in existing mathematics and biology courses, and we address a critical national need to introduce students to mathematical methods beyond the interface of biology with calculus. Based on ongoing research, and designed to use the project-based-learning approach, the modules highlight applications of modern discrete mathematics and algebraic statistics to pressing problems in molecular biology. For the majority of projects, calculus is not a required prerequisite and, due to the modest amount of mathematical background needed for some of the modules, the materials can be used for an early introduction to mathematical modeling. At the same time, most modules are connected with topics in linear and abstract algebra, algebraic geometry, and probability, and they can be used as meaningful applied introductions into the relevant advanced-level mathematics courses. Open-source software is used to facilitate the relevant computations. As a detailed example, we outline a module that focuses on Boolean models of the lac operon network.
Czocher, Jennifer A.
2016-01-01
This study contributes a methodological tool to reconstruct the cognitive processes and mathematical activities carried out by mathematical modelers. Represented as Modeling Transition Diagrams (MTDs), individual modeling routes were constructed for four engineering undergraduate students. Findings stress the importance and limitations of using…
Kartal, Ozgul; Dunya, Beyza Aksu; Diefes-Dux, Heidi A.; Zawojewski, Judith S.
2016-01-01
Critical to many science, technology, engineering, and mathematics (STEM) career paths is mathematical modeling--specifically, the creation and adaptation of mathematical models to solve problems in complex settings. Conventional standardized measures of mathematics achievement are not structured to directly assess this type of mathematical…
A taxonomy-based approach to shed light on the babel of mathematical models for rice simulation
Confalonieri, Roberto; Bregaglio, Simone; Adam, Myriam; Ruget, Françoise; Li, Tao; Hasegawa, Toshihiro; Yin, Xinyou; Zhu, Yan; Boote, Kenneth; Buis, Samuel; Fumoto, Tamon; Gaydon, Donald; Lafarge, Tanguy; Marcaida, Manuel; Nakagawa, Hiroshi; Ruane, Alex C.; Singh, Balwinder; Singh, Upendra; Tang, Liang; Tao, Fulu; Fugice, Job; Yoshida, Hiroe; Zhang, Zhao; Wilson, Lloyd T.; Baker, Jeff; Yang, Yubin; Masutomi, Yuji; Wallach, Daniel; Acutis, Marco; Bouman, Bas
2016-01-01
For most biophysical domains, differences in model structures are seldom quantified. Here, we used a taxonomy-based approach to characterise thirteen rice models. Classification keys and binary attributes for each key were identified, and models were categorised into five clusters using a binary
Controllability, Observability, and Stability of Mathematical Models
Iggidr, Abderrahman
2004-01-01
International audience; This article presents an overview of three fundamental concepts in Mathematical System Theory: controllability, stability and observability. These properties play a prominent role in the study of mathematical models and in the understanding of their behavior. They constitute the main research subject in Control Theory. Historically the tools and techniques of Automatic Control have been developed for artificial engineering systems but nowadays they are more and more ap...
Pieters, Stefanie; Roeyers, Herbert; Rosseel, Yves; Van Waelvelde, Hilde; Desoete, Annemie
2015-01-01
A relationship between motor and mathematical skills has been shown by previous research. However, the question of whether subtypes can be differentiated within developmental coordination disorder (DCD) and/or mathematical learning disability (MLD) remains unresolved. In a sample of children with and without DCD and/or MLD, a data-driven…
Students’ mathematical learning in modelling activities
DEFF Research Database (Denmark)
Kjeldsen, Tinne Hoff; Blomhøj, Morten
2013-01-01
involved. We argue that progress in students’ conceptual learning needs to be conceptualised separately from that of progress in their modelling competency. Findings are that modelling activities open a window to the students’ images of the mathematical concepts involved; that modelling activities can...
On the mathematical modeling of aeolian saltation
DEFF Research Database (Denmark)
Jensen, Jens Ledet; Sørensen, Michael
1983-01-01
The development of a mathematical model for aeolian saltation is a promising way of obtaining further progress in the field of wind-blown sand. Interesting quantities can be calculated from a model defined in general terms, and a specific model is defined and compared to previously published data...
Identification of Chemical Reactor Plant’s Mathematical Model
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Pyakillya Boris
2015-01-01
Full Text Available This work presents a solution of the identification problem of chemical reactor plant’s mathematical model. The main goal is to obtain a mathematical description of a chemical reactor plant from experimental data, which based on plant’s time response measurements. This data consists sequence of measurements for water jacket temperature and information about control input signal, which is used to govern plant’s behavior.
Mathematical modeling and applications in nonlinear dynamics
Merdan, Hüseyin
2016-01-01
The book covers nonlinear physical problems and mathematical modeling, including molecular biology, genetics, neurosciences, artificial intelligence with classical problems in mechanics and astronomy and physics. The chapters present nonlinear mathematical modeling in life science and physics through nonlinear differential equations, nonlinear discrete equations and hybrid equations. Such modeling can be effectively applied to the wide spectrum of nonlinear physical problems, including the KAM (Kolmogorov-Arnold-Moser (KAM)) theory, singular differential equations, impulsive dichotomous linear systems, analytical bifurcation trees of periodic motions, and almost or pseudo- almost periodic solutions in nonlinear dynamical systems. Provides methods for mathematical models with switching, thresholds, and impulses, each of particular importance for discontinuous processes Includes qualitative analysis of behaviors on Tumor-Immune Systems and methods of analysis for DNA, neural networks and epidemiology Introduces...
Mathematical Models of Tuberculosis Reactivation and Relapse
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Robert Steven Wallis
2016-05-01
Full Text Available The natural history of human infection with Mycobacterium tuberculosis (Mtb is highly variable, as is the response to treatment of active tuberculosis. There is presently no direct means to identify individuals in whom Mtb infection has been eradicated, whether by a bactericidal immune response or sterilizing antimicrobial chemotherapy. Mathematical models can assist in such circumstances by measuring or predicting events that cannot be directly observed. The 3 models discussed in this review illustrate instances in which mathematical models were used to identify individuals with innate resistance to Mtb infection, determine the etiology of tuberculosis in patients treated with tumor necrosis factor antagonists, and predict the risk of relapse in persons undergoing tuberculosis treatment. These examples illustrate the power of various types of mathematic models to increase knowledge and thereby inform interventions in the present global tuberculosis epidemic.
Interfacial Fluid Mechanics A Mathematical Modeling Approach
Ajaev, Vladimir S
2012-01-01
Interfacial Fluid Mechanics: A Mathematical Modeling Approach provides an introduction to mathematical models of viscous flow used in rapidly developing fields of microfluidics and microscale heat transfer. The basic physical effects are first introduced in the context of simple configurations and their relative importance in typical microscale applications is discussed. Then,several configurations of importance to microfluidics, most notably thin films/droplets on substrates and confined bubbles, are discussed in detail. Topics from current research on electrokinetic phenomena, liquid flow near structured solid surfaces, evaporation/condensation, and surfactant phenomena are discussed in the later chapters. This book also: Discusses mathematical models in the context of actual applications such as electrowetting Includes unique material on fluid flow near structured surfaces and phase change phenomena Shows readers how to solve modeling problems related to microscale multiphase flows Interfacial Fluid Me...
Mathematical models and methods for planet Earth
Locatelli, Ugo; Ruggeri, Tommaso; Strickland, Elisabetta
2014-01-01
In 2013 several scientific activities have been devoted to mathematical researches for the study of planet Earth. The current volume presents a selection of the highly topical issues presented at the workshop “Mathematical Models and Methods for Planet Earth”, held in Roma (Italy), in May 2013. The fields of interest span from impacts of dangerous asteroids to the safeguard from space debris, from climatic changes to monitoring geological events, from the study of tumor growth to sociological problems. In all these fields the mathematical studies play a relevant role as a tool for the analysis of specific topics and as an ingredient of multidisciplinary problems. To investigate these problems we will see many different mathematical tools at work: just to mention some, stochastic processes, PDE, normal forms, chaos theory.
Mathematical model in economic environmental problems
Energy Technology Data Exchange (ETDEWEB)
Nahorski, Z. [Polish Academy of Sciences, Systems Research Inst. (Poland); Ravn, H.F. [Risoe National Lab. (Denmark)
1996-12-31
The report contains a review of basic models and mathematical tools used in economic regulation problems. It starts with presentation of basic models of capital accumulation, resource depletion, pollution accumulation, and population growth, as well as construction of utility functions. Then the one-state variable model is discussed in details. The basic mathematical methods used consist of application of the maximum principle and phase plane analysis of the differential equations obtained as the necessary conditions of optimality. A summary of basic results connected with these methods is given in appendices. (au) 13 ills.; 17 refs.
Mathematical modeling of complex noise barriers
Energy Technology Data Exchange (ETDEWEB)
Hayek, S.I.
1982-01-01
Mathematical modeling of the noise reduction efficiency of highway noise barriers depends on the shape and absorptivity of the barrier, the influence of the impedance of the ground under the receiver, the atmospheric conditions as well as traffic details. The mathematical model for a barrier's noise reduction requires the knowledge of point-to-point acoustic diffraction models. In many instances, the shape of the barrier is simple; such as thin wall (edge), sharp wedge, and cylindrically topped berms. However, new designs of more efficient barriers have been investigated recently.
Mathematical Modeling in Continuum Mechanics
Temam, Roger; Miranville, Alain
2005-06-01
Temam and Miranville present core topics within the general themes of fluid and solid mechanics. The brisk style allows the text to cover a wide range of topics including viscous flow, magnetohydrodynamics, atmospheric flows, shock equations, turbulence, nonlinear solid mechanics, solitons, and the nonlinear Schrödinger equation. This second edition will be a unique resource for those studying continuum mechanics at the advanced undergraduate and beginning graduate level whether in engineering, mathematics, physics or the applied sciences. Exercises and hints for solutions have been added to the majority of chapters, and the final part on solid mechanics has been substantially expanded. These additions have now made it appropriate for use as a textbook, but it also remains an ideal reference book for students and anyone interested in continuum mechanics.
Energy Technology Data Exchange (ETDEWEB)
Biswas, J.; Chowdhury, R.; Bhattacharya, P. [Chemical Engineering Department, Jadavpur University, Kolkata 700 032 (India)
2007-01-15
An anaerobic digester of 10L capacity has been operated in batch mode at an optimum temperature of 40{sup o}C and at a pH of 6.8 using vegetable/food residues as the feed material. The effect of slurry concentration and that of the concentration of carbohydrate, protein and fat in the slurry on the biogas production rate and methane concentration in the biogas have been studied. The slurry concentration has been varied in the range of 72.0-700kgm{sup -3}. At a slurry concentration of 67.7kgm{sup -3} the effect of carbohydrate concentration has been studied by varying the ratios of carbohydrate, protein and fat in the range of 6.9:4.3:1-12.1:4.3:1 by using a sole carbohydrate source, namely sucrose. The effect of protein concentration has been studied by varying the ratios of carbohydrate, protein and fat in the range of 5.6:7.0:1-5.6:13.0:1 by using a sole protein source, namely papain and that of fat concentration has been studied by varying the ratios of carbohydrate, protein and fat in the range of 7.2:10:1.6-7.2:10:5 by using a fat source, namely vanaspati. A deterministic mathematical model using differential system equations have been developed and it is capable of predicting the behaviour of the digester satisfactorily. (author)
Zhou, Y.; Ji, Y.
2013-01-01
Precipitation is an important operation in biopharmaceutical purification yet the mechanism of protein precipitation in multi-component solutions is not well understood. Existing models lack fundamental understanding of the process. In this paper, a new model describing how the protein solubility changes in the protein precipitation is proposed and is based on the phase equilibrium of the light liquid phase and dense solid phase. The model structure is generic and robust. It adequately reflec...
About a mathematical model of market
Kulikov, D. A.
2017-01-01
In the paper a famous mathematical model of macroeconomics, which is called “market model” was considered. Traditional versions of this model have no periodic solutions and, therefore, they cannot describe a cyclic recurrence of the market economy. In the paper for the corresponding equation a delay was added. It allows obtaining sufficient conditions for existence of the stable cycles.
Mathematical model of electrotaxis in osteoblastic cells
Vanegas-Acosta, J.C.; Garzón-Alvarado, D.A.; Zwamborn, A.P.M.
2012-01-01
Electrotaxis is the cell migration in the presence of an electric field (EF). This migration is parallel to the EF vector and overrides chemical migration cues. In this paper we introduce a mathematical model for the electrotaxis in osteoblastic cells. The model is evaluated using different EF stren
Mathematical human body modelling for impact loading
Happee, R.; Morsink, P.L.J.; Wismans, J.S.H.M.
1999-01-01
Mathematical modelling of the human body is widely used for automotive crash safety research and design. Simulations have contributed to a reduction of injury numbers by optimisation of vehicle structures and restraint systems. Currently such simulations are largely performed using occupant models b
Mathematical models of cell self-organization
Directory of Open Access Journals (Sweden)
Benoît Perthame
2011-04-01
More recently nonlinear hyperbolic and kinetic models also have been used to describe the phenomena at a smaller scale. We explain here some motivations for ‘microscopic’ descriptions, the mathematical difficulties arising in their analysis and how kinetic models can help in understanding the unity of these descriptions.
Mathematical human modelling for impact loading
Happee, R.; Hoof, J.F.A.M. van; Lange, R. de
2001-01-01
Mathematical modeling of the human body is widely used for automotive crash-safety research and design. Simulations have contributed to a reduction of injury numbers by optimization of vehicle structures and restraint systems. Currently, such simulations are largely performed using occupant models b
Mathematical modelling of magnetically targeted drug delivery
Energy Technology Data Exchange (ETDEWEB)
Grief, Andrew D. [Theoretical Mechanics, School of Mathematical Sciences, University of Nottingham, University Park, Nottingham NG7 2RD (United Kingdom)]. E-mail: andrew.grief@nottingham.ac.uk; Richardson, Giles [Theoretical Mechanics, School of Mathematical Sciences, University of Nottingham, University Park, Nottingham NG7 2RD (United Kingdom)]. E-mail: giles.richardson@nottingham.ac.uk
2005-05-15
A mathematical model for targeted drug delivery using magnetic particles is developed. This includes a diffusive flux of particles arising from interactions between erythrocytes in the microcirculation. The model is used to track particles in a vessel network. Magnetic field design is discussed and we show that it is impossible to specifically target internal regions using an externally applied field.
Mathematical Modeling of Viral Zoonoses in Wildlife
2011-01-01
Zoonoses are a worldwide public health concern, accounting for approximately 75% of human infectious diseases. In addition, zoonoses adversely affect agricultural production and wildlife. We review some mathematical models developed for the study of viral zoonoses in wildlife and identify areas where further modeling efforts are needed.
A Taxonomy-Based Approach to Shed Light on the Babel of Mathematical Models for Rice Simulation
Confalonieri, Roberto; Bregaglio, Simone; Adam, Myriam; Ruget, Francoise; Li, Tao; Hasegawa, Toshihiro; Yin, Xinyou; Zhu, Yan; Boote, Kenneth; Buis, Samuel; Ruane, Alex C.
2016-01-01
For most biophysical domains, differences in model structures are seldom quantified. Here, we used a taxonomy-based approach to characterise thirteen rice models. Classification keys and binary attributes for each key were identified, and models were categorised into five clusters using a binary similarity measure and the unweighted pair-group method with arithmetic mean. Principal component analysis was performed on model outputs at four sites. Results indicated that (i) differences in structure often resulted in similar predictions and (ii) similar structures can lead to large differences in model outputs. User subjectivity during calibration may have hidden expected relationships between model structure and behaviour. This explanation, if confirmed, highlights the need for shared protocols to reduce the degrees of freedom during calibration, and to limit, in turn, the risk that user subjectivity influences model performance.
Developing Mathematics Problems Based on Pisa Level
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Shahibul Ahyan
2014-01-01
Full Text Available This research aims to produce mathematics problems based on PISA level with valid and practical content of change and relationships and has potential effect for Junior High School students. A development research method developed by Akker, Gravemeijer, McKenney and Nieveen is used this research. In the first stage, the researcher analyzed students, algebra material in school-based curricula (KTSP and mathematics problems of PISA 2003 of change and relationships content. The second stage, the researcher designed 13 problems with content of change and relationships. The last, the researcher used formative evaluation design developed by Tessmer which includes self evaluation, one-to-one, expert review, small group, and field test. The data collect by walk through, interview, and questionnaire. The result of this research indicated that 12 mathematical problems based on PISA level of change and relationships content that developed have validity, practically, and potential effects for Junior High School students.
A mathematical model of glutathione metabolism
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James S Jill
2008-04-01
Full Text Available Abstract Background Glutathione (GSH plays an important role in anti-oxidant defense and detoxification reactions. It is primarily synthesized in the liver by the transsulfuration pathway and exported to provide precursors for in situ GSH synthesis by other tissues. Deficits in glutathione have been implicated in aging and a host of diseases including Alzheimer's disease, Parkinson's disease, cardiovascular disease, cancer, Down syndrome and autism. Approach We explore the properties of glutathione metabolism in the liver by experimenting with a mathematical model of one-carbon metabolism, the transsulfuration pathway, and glutathione synthesis, transport, and breakdown. The model is based on known properties of the enzymes and the regulation of those enzymes by oxidative stress. We explore the half-life of glutathione, the regulation of glutathione synthesis, and its sensitivity to fluctuations in amino acid input. We use the model to simulate the metabolic profiles previously observed in Down syndrome and autism and compare the model results to clinical data. Conclusion We show that the glutathione pools in hepatic cells and in the blood are quite insensitive to fluctuations in amino acid input and offer an explanation based on model predictions. In contrast, we show that hepatic glutathione pools are highly sensitive to the level of oxidative stress. The model shows that overexpression of genes on chromosome 21 and an increase in oxidative stress can explain the metabolic profile of Down syndrome. The model also correctly simulates the metabolic profile of autism when oxidative stress is substantially increased and the adenosine concentration is raised. Finally, we discuss how individual variation arises and its consequences for one-carbon and glutathione metabolism.
Vos, Francisca; Roorda, Gerrit
2016-01-01
When students engage in rich mathematical modelling tasks, they have to handle real-world contexts and mathematics in chorus. This is not easy. In this chapter, contexts and mathematics are perceived as complementary, which means they can be integrated. Based on four types of approaches to modelling
Development of Mathematical Model on Preparation of Functionally Graded Material by Co-sedimentation
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
From the process of sedimentation the mathematical relationshipsamong deposition volume and powder properties as well as sedimentation parameters were deduced. Based on the formula a mathematical model was set up and simulated through the computer. At last the validity of mathematical model was supported by the representative experiment on Ti-Mo system FGM prepared by co-sedimentation.
Attitudes of Pre-Service Mathematics Teachers towards Modelling: A South African Inquiry
Jacobs, Gerrie J.; Durandt, Rina
2017-01-01
This study explores the attitudes of mathematics pre-service teachers, based on their initial exposure to a model-eliciting challenge. The new Curriculum and Assessment Policy Statement determines that mathematics students should be able to identify, investigate and solve problems via modelling. The unpreparedness of mathematics teachers in…
Mathematical Model of Silicon Oxidation in Microelectronics
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V. A. Bondarev
2006-01-01
Full Text Available The paper involves analytical solutions and formulae for determination of the oxide film thickness in the silicon oxidation while using nitride mask. Calculations are based on solutions of a three-dimensional diffusion equation and new mathematical functions that are firstly defined by the author. Suitable analytical and numerical solutions based on the diffusion equation have not yet been obtained
A mathematical model for Neanderthal extinction
Flores, J C
1997-01-01
A simple mathematical homogeneous model of competition is used to describe Neanderthal extinction in Europe. It considers two interacting species, Neanderthals and Early Modern Men, in the same ecological niche. Using paleontological data we claim that the parameter of similarity, between both species, fluctuates between 0.992 and 0.997. An extension of the model including migration (diffusion) is also discussed nevertheless, extinction of Neanderthal seems unavoidable. Numerical analysis of travelling wave solution (fronts) comfirms the extinction. The wave-front-velocity is estimated from linear analysis and numerical simulations confirm this estimation. We conjecture a mathematical formulation for the principle of exclusion between competitive interacting species (Gause).
On the mathematical modeling of memristors
Radwan, Ahmed G.
2012-10-06
Since the fourth fundamental element (Memristor) became a reality by HP labs, and due to its huge potential, its mathematical models became a necessity. In this paper, we provide a simple mathematical model of Memristors characterized by linear dopant drift for sinusoidal input voltage, showing a high matching with the nonlinear SPICE simulations. The frequency response of the Memristor\\'s resistance and its bounding conditions are derived. The fundamentals of the pinched i-v hysteresis, such as the critical resistances, the hysteresis power and the maximum operating current, are derived for the first time.
Dynamics of mathematical models in biology bringing mathematics to life
Zazzu, Valeria; Guarracino, Mario
2016-01-01
This volume focuses on contributions from both the mathematics and life science community surrounding the concepts of time and dynamicity of nature, two significant elements which are often overlooked in modeling process to avoid exponential computations. The book is divided into three distinct parts: dynamics of genomes and genetic variation, dynamics of motifs, and dynamics of biological networks. Chapters included in dynamics of genomes and genetic variation analyze the molecular mechanisms and evolutionary processes that shape the structure and function of genomes and those that govern genome dynamics. The dynamics of motifs portion of the volume provides an overview of current methods for motif searching in DNA, RNA and proteins, a key process to discover emergent properties of cells, tissues, and organisms. The part devoted to the dynamics of biological networks covers networks aptly discusses networks in complex biological functions and activities that interpret processes in cells. Moreover, chapters i...
Cocaine addiction and personality: a mathematical model.
Caselles, Antonio; Micó, Joan C; Amigó, Salvador
2010-05-01
The existence of a close relation between personality and drug consumption is recognized, but the corresponding causal connection is not well known. Neither is it well known whether personality exercises an influence predominantly at the beginning and development of addiction, nor whether drug consumption produces changes in personality. This paper presents a dynamic mathematical model of personality and addiction based on the unique personality trait theory (UPTT) and the general modelling methodology. This model attempts to integrate personality, the acute effect of drugs, and addiction. The UPTT states the existence of a unique trait of personality called extraversion, understood as a dimension that ranges from impulsive behaviour and sensation-seeking (extravert pole) to fearful and anxious behaviour (introvert pole). As a consequence of drug consumption, the model provides the main patterns of extraversion dynamics through a system of five coupled differential equations. It combines genetic extraversion, as a steady state, and dynamic extraversion in a unique variable measured on the hedonic scale. The dynamics of this variable describes the effects of stimulant drugs on a short-term time scale (typical of the acute effect); while its mean time value describes the effects of stimulant drugs on a long-term time scale (typical of the addiction effect). This understanding may help to develop programmes of prevention and intervention in drug misuse.
Mathematical Modeling Social Responsibility for Dynamic Organizations
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Farzaneh Chavoshbashi
2012-03-01
Full Text Available Dynamic organizations as accountable organizations, for transparency and accountability to its stakeholders to stakeholders for their toward performance there should express their commitment to social responsibility are through their values and ensure that this commitment throughout the organization are now and thus will have a social responsibility for their mutual benefit, so there is more and more coherent in their ethical approach takes advantage and the community and stakeholders and the organization will have better performance and strengths. Because of interest in social responsibility, in this paper dynamic model is presented for Corporate Social Responsibility of Bionic organization. Model presented a new model is inspired by chaos theory and natural systems theory based on bifurcation in creation to be all natural systems, realizing the value of responsibility as one of the fundamental values of social and institutional development that the relationship between business and work environment in the global market economy and range will be specified. First Social Responsibility factors identified, then experts and scholars determine the weight of the components and technical coefficient for modeling and paired comparison has been done using MATLAB mathematical Software.
Mathematical modeling of a rotary hearth coke calciner
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Hilde C. Meisingset
1995-10-01
Full Text Available A mathematical model of a rotary hearth coke calciner is developed. The model is based on first principles including the most important dynamic phenomena. The model is a thermodynamic model involving heat and mass transfer and chemical reactions. Fundamental mass and energy balance equations for the coke phase, the gas phase and the lining are formulated. For the gas phase, a stationary model is used. The equations are solved numerically, and simulated temperature profiles are shown in this paper.
Mathematical modeling of endovenous laser treatment (ELT
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Wassmer Benjamin
2006-04-01
Full Text Available Abstract Background and objectives Endovenous laser treatment (ELT has been recently proposed as an alternative in the treatment of reflux of the Great Saphenous Vein (GSV and Small Saphenous Vein (SSV. Successful ELT depends on the selection of optimal parameters required to achieve an optimal vein damage while avoiding side effects. Mathematical modeling of ELT could provide a better understanding of the ELT process and could determine the optimal dosage as a function of vein diameter. Study design/materials and methods The model is based on calculations describing the light distribution using the diffusion approximation of the transport theory, the temperature rise using the bioheat equation and the laser-induced injury using the Arrhenius damage model. The geometry to simulate ELT was based on a 2D model consisting of a cylindrically symmetric blood vessel including a vessel wall and surrounded by an infinite homogenous tissue. The mathematical model was implemented using the Macsyma-Pdease2D software (Macsyma Inc., Arlington, MA, USA. Damage to the vein wall for CW and single shot energy was calculated for 3 and 5 mm vein diameters. In pulsed mode, the pullback distance (3, 5 and 7 mm was considered. For CW mode simulation, the pullback speed (1, 2, 3 mm/s was the variable. The total dose was expressed as joules per centimeter in order to perform comparison to results already reported in clinical studies. Results In pulsed mode, for a 3 mm vein diameter, irrespective of the pullback distance (2, 5 or 7 mm, a minimum fluence of 15 J/cm is required to obtain a permanent damage of the intima. For a 5 mm vein diameter, 50 J/cm (15W-2s is required. In continuous mode, for a 3 mm and 5 mm vein diameter, respectively 65 J/cm and 100 J/cm are required to obtain a permanent damage of the vessel wall. Finally, the use of different wavelengths (810 nm or 980 nm played only a minor influence on these results. Discussion and conclusion The parameters
Mathematical Modelling of Unmanned Aerial Vehicles
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Saeed Sarwar
2013-04-01
Full Text Available UAVs (Unmanned Arial Vehicleis UAVs are emerging as requirement of time and it is expected that in next five to ten years, complete air space will be flooded with UAVs, committed in varied assignments ranging from military, scientific and commercial usage. Non availability of human pilot inside UAV necessitates the requirement of an onboard autopilot in order to maintain desired flight profile against any unexpected disturbance and/or parameter variations. Design of such an autopilot requires an accurate mathematical model of UAV. The aim of this paper is to present a consolidated picture of UAV model. This paper first consolidates complete 6 DOF Degree of Freedom equations of motion into a nonlinear mathematical model and its simulation using model parameters of a real UAV. Model is then linearized into longitudinal and lateral modes. State space models of linearized modes are simulated and analyzed for stability parameters. The developed model can be used to design autopilot for UAV
基于数学模型的雨水调蓄计算%Calculation of Rainwater Storage Based on Mathematical Model
Institute of Scientific and Technical Information of China (English)
杨伟伟; 刘绍根; 李卫华; 李继选
2016-01-01
雨水调蓄系统是城市防洪排涝工程的重要措施,合理、科学地确定雨水调蓄设施的调蓄容积具有重要意义.针对安徽省繁昌县城北开发区经常受涝的现状,采用了传统雨水调蓄容积计算和基于数学模型的雨水调蓄容积计算分别校核区内雨水调蓄设施的调蓄容积,结果表明,基于数学模型的雨水调蓄容积计算更为安全、可靠,可以为类似工程提供参考.%Rainwater storage system is an important measure for city flood prevention and drainage project,so reasonable and scientific determination of rainwater storage volume has important significance.Considering the frequent waterlogging in the North Development Zone of Fanchang County,Anhui Province,the volume of rainwater storage facilities was checked by the traditional calculation method of rainwater storage volume and the calculation method based on mathematical model.The results showed that the calculation method based on mathematical model was more safe and reliable,which can provide reference for similar projects.
Wardono; Waluya, S. B.; Mariani, Scolastika; Candra D, S.
2016-02-01
This study aims to find out that there are differences in mathematical literacy ability in content Change and Relationship class VII Junior High School 19, Semarang by Problem Based Learning (PBL) model with an Indonesian Realistic Mathematics Education (called Pendidikan Matematika Realistik Indonesia or PMRI in Indonesia) approach assisted Elearning Edmodo, PBL with a PMRI approach, and expository; to know whether the group of students with learning PBL models with PMRI approach and assisted E-learning Edmodo can improve mathematics literacy; to know that the quality of learning PBL models with a PMRI approach assisted E-learning Edmodo has a good category; to describe the difficulties of students in working the problems of mathematical literacy ability oriented PISA. This research is a mixed methods study. The population was seventh grade students of Junior High School 19, Semarang Indonesia. Sample selection is done by random sampling so that the selected experimental class 1, class 2 and the control experiment. Data collected by the methods of documentation, tests and interviews. From the results of this study showed average mathematics literacy ability of students in the group PBL models with a PMRI approach assisted E-learning Edmodo better than average mathematics literacy ability of students in the group PBL models with a PMRI approach and better than average mathematics literacy ability of students in the expository models; Mathematics literacy ability in the class using the PBL model with a PMRI approach assisted E-learning Edmodo have increased and the improvement of mathematics literacy ability is higher than the improvement of mathematics literacy ability of class that uses the model of PBL learning with PMRI approach and is higher than the improvement of mathematics literacy ability of class that uses the expository models; The quality of learning using PBL models with a PMRI approach assisted E-learning Edmodo have very good category.
Applied Mathematics, Modelling and Computational Science
Kotsireas, Ilias; Makarov, Roman; Melnik, Roderick; Shodiev, Hasan
2015-01-01
The Applied Mathematics, Modelling, and Computational Science (AMMCS) conference aims to promote interdisciplinary research and collaboration. The contributions in this volume cover the latest research in mathematical and computational sciences, modeling, and simulation as well as their applications in natural and social sciences, engineering and technology, industry, and finance. The 2013 conference, the second in a series of AMMCS meetings, was held August 26–30 and organized in cooperation with AIMS and SIAM, with support from the Fields Institute in Toronto, and Wilfrid Laurier University. There were many young scientists at AMMCS-2013, both as presenters and as organizers. This proceedings contains refereed papers contributed by the participants of the AMMCS-2013 after the conference. This volume is suitable for researchers and graduate students, mathematicians and engineers, industrialists, and anyone who would like to delve into the interdisciplinary research of applied and computational mathematics ...
Mathematical models to characterize early epidemic growth: A review
Chowell, Gerardo; Sattenspiel, Lisa; Bansal, Shweta; Viboud, Cécile
2016-09-01
There is a long tradition of using mathematical models to generate insights into the transmission dynamics of infectious diseases and assess the potential impact of different intervention strategies. The increasing use of mathematical models for epidemic forecasting has highlighted the importance of designing reliable models that capture the baseline transmission characteristics of specific pathogens and social contexts. More refined models are needed however, in particular to account for variation in the early growth dynamics of real epidemics and to gain a better understanding of the mechanisms at play. Here, we review recent progress on modeling and characterizing early epidemic growth patterns from infectious disease outbreak data, and survey the types of mathematical formulations that are most useful for capturing a diversity of early epidemic growth profiles, ranging from sub-exponential to exponential growth dynamics. Specifically, we review mathematical models that incorporate spatial details or realistic population mixing structures, including meta-population models, individual-based network models, and simple SIR-type models that incorporate the effects of reactive behavior changes or inhomogeneous mixing. In this process, we also analyze simulation data stemming from detailed large-scale agent-based models previously designed and calibrated to study how realistic social networks and disease transmission characteristics shape early epidemic growth patterns, general transmission dynamics, and control of international disease emergencies such as the 2009 A/H1N1 influenza pandemic and the 2014-2015 Ebola epidemic in West Africa.
The (mathematical modelling process in biosciences
Directory of Open Access Journals (Sweden)
Nestor V. Torres
2015-12-01
Full Text Available In this communication we introduce a general framework and discussion on the role of models and the modelling process within the scientific activity in the biosciences realm. The objective is sum up the common procedure during the formalization and analysis of a biological problem under the foundations of Systems Biology, which approach the study of biological systems as a whole.We begin by presenting the definitions of (biological system and model. Particular attention is given to the meaning of mathematical model within the context of the biology. Then, we present the modelization and analysis process of biological systems. Three stages are described in detail: conceptualization of the biological system into a model, mathematical formalization of the previous conceptual model and optimization and system management derived from the analysis of the mathematical model.All along this presentation the main features and shortcomings of the process are developed together with a set of rules that could help in the modelling endeavour of any biological system. Special regard is given to the formative requirements and the interdisciplinary nature of this approach. We conclude with some general considerations on the challenges that the modelling are currently posing to the current biology.
Dog Mathematics: Exploring Base-4
Kurz, Terri L.; Yanik, H. Bahadir; Lee, Mi Yeon
2016-01-01
Using a dog's paw as a basis for numerical representation, sixth grade students explored how to count and regroup using the dog's four digital pads. Teachers can connect these base-4 explorations to the conceptual meaning of place value and regrouping using base-10.
Mathematical System Theory and System Modeling
1980-01-01
Choosing models related effectively to the questions to be addressed is a central issue in the craft of systems analysis. Since the mathematical description the analyst chooses constrains the types of issues he candeal with, it is important for these models to be selected so as to yield limitations that are acceptable in view of the questions the systems analysis seeks to answer. In this paper, the author gives an overview of the central issues affecting the question of model choice. To ...
Mathematical Modelling of Bridges with SAP2000
Maraž, Miha
2006-01-01
The present work describes a relatively new programme module, which is enhanced in the recently released versions of SAP2000 software. The new module, called Bridge Modeler, is intended for simple, parametric mathematical modelling of bridges. The modelling procedure is explained on a test case through the steps of a user-friendly Bridge Wizard. For each step, we described the basic principles and the application possibilities as well as some limitations. We also explained two types of analys...
What Is Known about Elementary Grades Mathematical Modelling
Directory of Open Access Journals (Sweden)
Micah S. Stohlmann
2016-01-01
Full Text Available Mathematical modelling has often been emphasized at the secondary level, but more research is needed at the elementary level. This paper serves to summarize what is known about elementary mathematical modelling to guide future research. A targeted and general literature search was conducted and studies were summarized based on five categories: content of mathematical modelling intervention, assessment data collected, unit of analysis studied, population, and effectiveness. It was found that there were three main units of analysis into which the studies could be categorized: representational and conceptual competence, models created, and student beliefs. The main findings from each of these units of analysis are discussed along with future research that is needed.
Optimization and mathematical modeling in computer architecture
Sankaralingam, Karu; Nowatzki, Tony
2013-01-01
In this book we give an overview of modeling techniques used to describe computer systems to mathematical optimization tools. We give a brief introduction to various classes of mathematical optimization frameworks with special focus on mixed integer linear programming which provides a good balance between solver time and expressiveness. We present four detailed case studies -- instruction set customization, data center resource management, spatial architecture scheduling, and resource allocation in tiled architectures -- showing how MILP can be used and quantifying by how much it outperforms t
Mathematical modeling of the flash converting process
Energy Technology Data Exchange (ETDEWEB)
Sohn, H.Y.; Perez-Tello, M.; Riihilahti, K.M. [Utah Univ., Salt Lake City, UT (United States)
1996-12-31
An axisymmetric mathematical model for the Kennecott-Outokumpu flash converting process for converting solid copper matte to copper is presented. The model is an adaptation of the comprehensive mathematical model formerly developed at the University of Utah for the flash smelting of copper concentrates. The model incorporates the transport of momentum, heat, mass, and reaction kinetics between gas and particles in a particle-laden turbulent gas jet. The standard k-{epsilon} model is used to describe gas-phase turbulence in an Eulerian framework. The particle-phase is treated from a Lagrangian viewpoint which is coupled to the gas-phase via the source terms in the Eulerian gas-phase governing equations. Matte particles were represented as Cu{sub 2}S yFeS, and assumed to undergo homogeneous oxidation to Cu{sub 2}O, Fe{sub 3}O{sub 4}, and SO{sub 2}. A reaction kinetics mechanism involving both external mass transfer of oxygen gas to the particle surface and diffusion of oxygen through the porous oxide layer is proposed to estimate the particle oxidation rate Predictions of the mathematical model were compared with the experimental data collected in a bench-scale flash converting facility. Good agreement between the model predictions and the measurements was obtained. The model was used to study the effect of different gas-injection configurations on the overall fluid dynamics in a commercial size flash converting shaft. (author)
Mathematical modeling models, analysis and applications
Banerjee, Sandip
2014-01-01
""…the reader may find quite a few interesting examples illustrating several important methods used in applied mathematics. … it may be well used as a valuable source of interesting examples as well as complementary reading in a number of courses.""-Svitlana P. Rogovchenko, Zentralblatt MATH 1298
Determining the Views of Mathematics Student Teachers Related to Mathematical Modelling
Tekin, Ayse; Kula, Semiha; Hidiroglu, Caglar Naci; Bukova-Guzel, Esra; Ugurel, Isikhan
2012-01-01
The purpose of this qualitative research is to examine the views of 21 secondary mathematics student teachers attending Mathematical Modelling Course regarding mathematical modelling in a state university in Turkey; reasons why they chose this course and their expectations from the course in question. For this reason, three open-ended questions…
Causal Bayes Model of Mathematical Competence in Kindergarten
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Božidar Tepeš
2016-06-01
Full Text Available In this paper authors define mathematical competences in the kindergarten. The basic objective was to measure the mathematical competences or mathematical knowledge, skills and abilities in mathematical education. Mathematical competences were grouped in the following areas: Arithmetic and Geometry. Statistical set consisted of 59 children, 65 to 85 months of age, from the Kindergarten Milan Sachs from Zagreb. The authors describe 13 variables for measuring mathematical competences. Five measuring variables were described for the geometry, and eight measuring variables for the arithmetic. Measuring variables are tasks which children solved with the evaluated results. By measuring mathematical competences the authors make causal Bayes model using free software Tetrad 5.2.1-3. Software makes many causal Bayes models and authors as experts chose the model of the mathematical competences in the kindergarten. Causal Bayes model describes five levels for mathematical competences. At the end of the modeling authors use Bayes estimator. In the results, authors describe by causal Bayes model of mathematical competences, causal effect mathematical competences or how intervention on some competences cause other competences. Authors measure mathematical competences with their expectation as random variables. When expectation of competences was greater, competences improved. Mathematical competences can be improved with intervention on causal competences. Levels of mathematical competences and the result of intervention on mathematical competences can help mathematical teachers.
Zhang, Pei; Li, Yi
2016-03-01
Existing prediction models of soil organic matter content (SOC) are restricted by some factors, such as sampling scale, soil type and spectral parameters of samples. Therefore, it is necessary to make a comparative analysis on larger scales to build a quantitative model with better feasibility and greater accuracy. A total of 225 soil samples were collected in an extensive region of the upper reaches of Heihe river basin. SOC and spectral reflectance were being measured. All the samples were divided into 2 subsets--a modeling subset (180 samples) and a validation subset (45 samples). Six indices were obtained through transformation of soil spectral reflectance (R), continuum-removal (CR), reciprocal (REC), logarithm of reciprocal (LR), first-order differential (FDR) and Kubelka-Munck transformation coefficient (K-M). To build the mathematical model of SOC with 12 spectral indices, two methods, i. e., stepwise linear regression and partial least-square regression were used based on the modeling subset, respectively; the validation subset is used for model evaluation. The results indicated that, (1) Regardless of different modeling methods, model between SOC and LR index was always the best among the 6 reflectance-related indices. LR was the best index for predicting SOC; (2) For the model based on the LR index, the accuracy of model using partial least-square regression method was better than that using stepwise linear regression method; (3) 225 samples were compared to verify the former available published SOC model. Both the predicted and measured values passed the mean value t-test, and the Pearson correlation coefficient reached 0.826. It shows that local prediction model can be applied to the research of predicting SOC in the larger scale.
Bukova-Guzel, Esra; Canturk-Gunhan, Berna
2011-01-01
The purpose of the study is to determine prospective mathematics teachers' views about using computer-based instructional materials in constructing mathematical concepts and to reveal how the sample computer-based instructional materials for different mathematical concepts altered their views. This is a qualitative study involving twelve…
Mathematical modeling of rewarming after cold therapy.
Avet, L M
1978-07-01
Statistical methods are presented for fitting mathematical models to skin temperature data. Three types of regression curves, namely, linear regression (Y = A + BX), second-degree regression (Y = A + BX + CX2), and asymptotic regression (Y = alpha + betapx), are discussed as possible models for the rewarming process following cold therapy. The data for fitting the curves consists of back surface temperature (degrees C) corresponding to various times after cold pack treatment (19 degrees C, administered for 20 minutes) was terminated.
Optimization of mathematical models for thematic maps
Institute of Scientific and Technical Information of China (English)
无
2010-01-01
The thematic map is a major class of maps designed to demonstrate particular features or concepts,functioning as an indispensable tool in geographical research.The process of thematic mapping is one into which geographical research goes deeply and broadly.The key activity and course of thematic map production is the use of mathematical models to create thematic data layers.Therefore,the selection and optimization of mathematical models is in the forefront of thematic map research.The theoretical foundations,mechanisms and methods of mathematical model optimization are expounded in this paper,including two approaches,the phase by phase mode and the multi-aim scheme balance mode.Case studies in eco-environment mapping and emergency mapping are described and analyzed,with a hierarchical analysis method being used in the model optimization for eco-environment fragility and sensitivity assessment mapping in Beibuwan (Guangxi) District,the dynamic system (DS) method being used in the model optimization for ecological security adjustment mapping in Xishuang Banna,Yunnan province,and the multi-phase mode being used in the models for forest fire and infectious diseases mapping.
On computer-based assessment of mathematics
Pead, Daniel
2010-01-01
This work explores some issues arising from the widespread use of computer based assessment of Mathematics in primary and secondary education. In particular, it considers the potential of computer based assessment for testing “process skills” and “problem solving”. This is discussed through a case study of the World Class Tests project which set out to test problem solving skills. The study also considers how on-screen “eAssessment” differs from conventional paper tests and how transferri...
Models and structures: mathematical physics
Energy Technology Data Exchange (ETDEWEB)
NONE
2003-07-01
This document gathers research activities along 5 main directions. 1) Quantum chaos and dynamical systems. Recent results concern the extension of the exact WKB method that has led to a host of new results on the spectrum and wave functions. Progress have also been made in the description of the wave functions of chaotic quantum systems. Renormalization has been applied to the analysis of dynamical systems. 2) Combinatorial statistical physics. We see the emergence of new techniques applied to various such combinatorial problems, from random walks to random lattices. 3) Integrability: from structures to applications. Techniques of conformal field theory and integrable model systems have been developed. Progress is still made in particular for open systems with boundary conditions, in connection to strings and branes physics. Noticeable links between integrability and exact WKB quantization to 2-dimensional disordered systems have been highlighted. New correlations of eigenvalues and better connections to integrability have been formulated for random matrices. 4) Gravities and string theories. We have developed aspects of 2-dimensional string theory with a particular emphasis on its connection to matrix models as well as non-perturbative properties of M-theory. We have also followed an alternative path known as loop quantum gravity. 5) Quantum field theory. The results obtained lately concern its foundations, in flat or curved spaces, but also applications to second-order phase transitions in statistical systems.
Mathematical modeling of the aerodynamic characteristics in flight dynamics
Tobak, M.; Chapman, G. T.; Schiff, L. B.
1984-01-01
Basic concepts involved in the mathematical modeling of the aerodynamic response of an aircraft to arbitrary maneuvers are reviewed. The original formulation of an aerodynamic response in terms of nonlinear functionals is shown to be compatible with a derivation based on the use of nonlinear functional expansions. Extensions of the analysis through its natural connection with ideas from bifurcation theory are indicated.
Mathematical modeling of biomass fuels formation process.
Gaska, Krzysztof; Wandrasz, Andrzej J
2008-01-01
The increasing demand for thermal and electric energy in many branches of industry and municipal management accounts for a drastic diminishing of natural resources (fossil fuels). Meanwhile, in numerous technical processes, a huge mass of wastes is produced. A segregated and converted combustible fraction of the wastes, with relatively high calorific value, may be used as a component of formed fuels. The utilization of the formed fuel components from segregated groups of waste in associated processes of co-combustion with conventional fuels causes significant savings resulting from partial replacement of fossil fuels, and reduction of environmental pollution resulting directly from the limitation of waste migration to the environment (soil, atmospheric air, surface and underground water). The realization of technological processes with the utilization of formed fuel in associated thermal systems should be qualified by technical criteria, which means that elementary processes as well as factors of sustainable development, from a global viewpoint, must not be disturbed. The utilization of post-process waste should be preceded by detailed technical, ecological and economic analyses. In order to optimize the mixing process of fuel components, a mathematical model of the forming process was created. The model is defined as a group of data structures which uniquely identify a real process and conversion of this data in algorithms based on a problem of linear programming. The paper also presents the optimization of parameters in the process of forming fuels using a modified simplex algorithm with a polynomial worktime. This model is a datum-point in the numerical modeling of real processes, allowing a precise determination of the optimal elementary composition of formed fuels components, with assumed constraints and decision variables of the task.
Mathematical Modeling for Preservice Teachers: A Problem from Anesthesiology.
Lingefjard, Thomas
2002-01-01
Addresses the observed actions of prospective Swedish mathematics teachers as they worked with a modeling situation. Explores prospective teachers' preparation to teach in grades 4-12 during a course of mathematical modeling. Focuses on preservice teachers' understanding of modeling and how they relate mathematical models to the real world.…
Use of mathematical modeling in nuclear measurements projects
Energy Technology Data Exchange (ETDEWEB)
Toubon, H.; Menaa, N.; Mirolo, L.; Ducoux, X.; Khalil, R. A. [AREVA/CANBERRA Nuclear Measurements Business Unit, Saint Quentin-en-Yvelines 78182 (France); Chany, P. [AREVA/BE Nuclear Sites Value Development AREVA NC Marcoule, BP 76170, 30206 Bagnols Sur Ceze (France); Devita, A. [AREVA/BE MELOX, BP 124, 30206 Bagnols Sur Ceze (France)
2011-07-01
Mathematical modeling of nuclear measurement systems is not a new concept. The response of the measurement system is described using a pre-defined mathematical model that depends on a set of parameters. These parameters are determined using a limited set of experimental measurement points e.g. efficiency curve, dose rates... etc. The model that agrees with the few experimental points is called an experimentally validated model. Once these models have been validated, we use mathematical interpolation to find the parameters of interest. Sometimes, when measurements are not practical or are impossible extrapolation is implemented but with care. CANBERRA has been extensively using mathematical modeling for the design and calibration of large and sophisticated systems to create and optimize designs that would be prohibitively expensive with only experimental tools. The case studies that will be presented here are primarily performed with MCNP, CANBERRA's MERCURAD/PASCALYS and ISOCS (In Situ Object Counting Software). For benchmarking purposes, both Monte Carlo and ray-tracing based codes are inter-compared to show models consistency and add a degree of reliability to modeling results. (authors)
Building Mathematical Models of Simple Harmonic and Damped Motion.
Edwards, Thomas
1995-01-01
By developing a sequence of mathematical models of harmonic motion, shows that mathematical models are not right or wrong, but instead are better or poorer representations of the problem situation. (MKR)
Bucur, Amelia
2015-09-01
The aim of this paper is to present aspects of mathematical modeling for the hierarchization of study programs from universities, based on several quality characteristics. The tools used pertain to multicriterial optimization, to the different methods of assessing importance coefficients, to the utility theory, the fuzzy formalism, and to the fuzzy simple additive weighting method. The conclusion is that multicriterial decision-making methods can be efficiently used in assessing the quality of study programs, noting that, just like other methods from the decision theory, the multicriterial decision-making methods highlight aspects of problems differently, therefore, there can be no comparison or competitiveness between them, and choosing one over the other is up to the decision-maker.
DEFF Research Database (Denmark)
Tajsoleiman, Tannaz; J. Abdekhodaie, Mohammad; Gernaey, Krist
2016-01-01
simulation of cartilage cell culture under a perfusion flow, which allows not only to characterize the supply of nutrients and metabolic products inside a fibrous scaffold, but also to assess the overall culture condition and predict the cell growth rate. Afterwards, the simulation results supported finding...... an optimized design of the scaffold within a new mathematical optimization algorithm that is proposed. The main concept of this optimization routine isto maintain a large effective surface while simultaneously keeping the shear stress levelin an operating range that is expected to be supporting growth...
Mathematical Modeling of Photochemical Air Pollution.
McRae, Gregory John
Air pollution is an environmental problem that is both pervasive and difficult to control. An important element of any rational control approach is a reliable means for evaluating the air quality impact of alternative abatement measures. This work presents such a capability, in the form of a mathematical description of the production and transport of photochemical oxidants within an urban airshed. The combined influences of advection, turbulent diffusion, chemical reaction, emissions and surface removal processes are all incorporated into a series of models that are based on the species continuity equations. A delineation of the essential assumptions underlying the formulation of a three-dimensional, a Lagrangian trajectory, a vertically integrated and single cell air quality model is presented. Since each model employs common components and input data the simpler forms can be used for rapid screening calculations and the more complex ones for detailed evaluations. The flow fields, needed for species transport, are constructed using inverse distance weighted polynomial interpolation techniques that map routine monitoring data onto a regular computational mesh. Variational analysis procedures are then employed to adjust the field so that mass is conserved. Initial concentration and mixing height distributions can be established with the same interpolation algorithms. Subgrid scale turbulent transport is characterized by a gradient diffusion hypothesis. Similarity solutions are used to model the surface layer fluxes. Above this layer different treatments of turbulent diffusivity are required to account for variations in atmospheric stability. Convective velocity scaling is utilized to develop eddy diffusivities for unstable conditions. The predicted mixing times are in accord with results obtained during sulfur hexafluoride (SF(,6)) tracer experiments. Conventional models are employed for neutral and stable conditions. A new formulation for gaseous deposition fluxes
Directory of Open Access Journals (Sweden)
Nikolić Igor M.
2006-01-01
Full Text Available Background. The use of computer models for the 3- dimensional reconstruction could be a reliable method to overcome technical imperfections of diagnostic procedures for the microsurgical operation of giant intracranial aneurysms. Case report. We presented a case of successfully operated 52-year-old woman with giant intracranial aneurysm, in which the computer 3-dimensional reconstruction of blood vessels and the aneurysmal neck had been decisive for making the diagnosis. The model for 3- dimensional reconstruction of blood vessels was based on the two 2-dimensional projections of the conventional angiography. Standard neuroradiologic diagnostic procedures showed a giant aneurysm on the left middle cerebral artery, but the conventional subtraction and CT angiography did not reveal enough information. By the use of a personal computer, we performed a 3-dimensional spatial reconstruction of the left carotid artery to visualize the neck of aneurysm and its supplying blood vessels. Conclusion. The 3-dimensional spatial reconstruction of the cerebral vessels of a giant aneurysm based on the conventional angiography could be useful for planning the surgical procedure.
Mathematical Modeling of an Automobile Damper
Directory of Open Access Journals (Sweden)
N. B. Kate, T. A. Jadhav
2013-10-01
Full Text Available - In an automotive industry, to reduce product development time and increase quality of product, it is essential to reduce the number of physical prototypes and rely more on precise & reliable design for the final design of vehicles. This paper presents a mathematical model for the damping force of the hydraulic shock absorber which is implemented to analyse the shock absorbers mounting brackets attached to the vehicle structure. Physical testing results indicate that the considered shock absorber’s mathematical model is reliable and can be used to calculate the durability target life of mounting brackets. Thus this presented methodology can be utilized as an effective way to reduce time and cost in design and development of automotive components.
Mathematical modelling of the lower urinary tract.
Paya, Antonio Soriano; Fernandez, Daniel Ruiz; Gil, David; Garcia Chamizo, Juan Manuel; Perez, Francisco Macia
2013-03-01
The lower urinary tract is one of the most complex biological systems of the human body as it involved hydrodynamic properties of urine and muscle. Moreover, its complexity is increased to be managed by voluntary and involuntary neural systems. In this paper, a mathematical model of the lower urinary tract it is proposed as a preliminary study to better understand its functioning. Furthermore, another goal of that mathematical model proposal is to provide a basis for developing artificial control systems. Lower urinary tract is comprised of two interacting systems: the mechanical system and the neural regulator. The latter has the function of controlling the mechanical system to perform the voiding process. The results of the tests reproduce experimental data with high degree of accuracy. Also, these results indicate that simulations not only with healthy patients but also of patients with dysfunctions with neurological etiology present urodynamic curves very similar to those obtained in clinical studies.
Directory of Open Access Journals (Sweden)
Iwami Shingo
2012-02-01
Full Text Available Abstract Background Developing a quantitative understanding of viral kinetics is useful for determining the pathogenesis and transmissibility of the virus, predicting the course of disease, and evaluating the effects of antiviral therapy. The availability of data in clinical, animal, and cell culture studies, however, has been quite limited. Many studies of virus infection kinetics have been based solely on measures of total or infectious virus count. Here, we introduce a new mathematical model which tracks both infectious and total viral load, as well as the fraction of infected and uninfected cells within a cell culture, and apply it to analyze time-course data of an SHIV infection in vitro. Results We infected HSC-F cells with SHIV-KS661 and measured the concentration of Nef-negative (target and Nef-positive (infected HSC-F cells, the total viral load, and the infectious viral load daily for nine days. The experiments were repeated at four different MOIs, and the model was fitted to the full dataset simultaneously. Our analysis allowed us to extract an infected cell half-life of 14.1 h, a half-life of SHIV-KS661 infectiousness of 17.9 h, a virus burst size of 22.1 thousand RNA copies or 0.19 TCID50, and a basic reproductive number of 62.8. Furthermore, we calculated that SHIV-KS661 virus-infected cells produce at least 1 infectious virion for every 350 virions produced. Conclusions Our method, combining in vitro experiments and a mathematical model, provides detailed quantitative insights into the kinetics of the SHIV infection which could be used to significantly improve the understanding of SHIV and HIV-1 pathogenesis. The method could also be applied to other viral infections and used to improve the in vitro determination of the effect and efficacy of antiviral compounds.
Modeling eBook acceptance: A study on mathematics teachers
Jalal, Azlin Abd; Ayub, Ahmad Fauzi Mohd; Tarmizi, Rohani Ahmad
2014-12-01
The integration and effectiveness of eBook utilization in Mathematics teaching and learning greatly relied upon the teachers, hence the need to understand their perceptions and beliefs. The eBook, an individual laptop completed with digitized textbook sofwares, were provided for each students in line with the concept of 1 student:1 laptop. This study focuses on predicting a model on the acceptance of the eBook among Mathematics teachers. Data was collected from 304 mathematics teachers in selected schools using a survey questionnaire. The selection were based on the proportionate stratified sampling. Structural Equation Modeling (SEM) were employed where the model was tested and evaluated and was found to have a good fit. The variance explained for the teachers' attitude towards eBook is approximately 69.1% where perceived usefulness appeared to be a stronger determinant compared to perceived ease of use. This study concluded that the attitude of mathematics teachers towards eBook depends largely on the perception of how useful the eBook is on improving their teaching performance, implying that teachers should be kept updated with the latest mathematical application and sofwares to use with the eBook to ensure positive attitude towards using it in class.
Mathematical modelling of wood and briquettes torrefaction
Energy Technology Data Exchange (ETDEWEB)
Felfli, Felix Fonseca; Luengo, Carlos Alberto [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Inst. de Fisica Gleb Wataghin. Grupo Combustiveis Alternativos; Soler, Pedro Beaton [Universidad de Oriente, Santiago de Cuba (Cuba). Fac. de Ingenieria Mecanica. Centro de Estudios de Eficiencia Energetica; Rocha, Jose Dilcio [Universidade Estadual de Campinas (UNICAMP), SP (Brazil). Nucleo Interdisciplinar de Planejamento Energetico (NIPE)
2004-07-01
A mathematical model valid for the torrefaction of wood logs and biomass briquettes is presented. The model described both chemical and physical processes, which take place in a moist piece of wood heated at temperatures between 503 and 573 K. Calibration measurements of the temperature profile and mass loss, were performed on dry cylinders of wood samples during torrefaction in an inert atmosphere at 503, 533, and 553 K. The calculated data shows a good agreement with experiments. The model can be a useful tool to estimate projecting and operating parameters for torrefaction furnaces such as minimum time of torrefaction, energy consumption and the mass yield. (author)
Study on mathematical model of steam coal blending
Institute of Scientific and Technical Information of China (English)
高洪阁; 李白英; 刘泽常; 尹增德
2002-01-01
It is necessary to set up a new mathematical model of steam coal blending instead of the old model. Indexes such as moisture content, ash content, volatile matter, sulfur content and heating value in the new mathematical model have linear relation. The new mathematical model can also predict ash-fusion temperature precisely by considering coal ash ratio in steam coal blending, therefore it is possible to obtain linear relation of ash-fusion temperature between single coal and steam coal blending. The new mathematical model can improve precision of steam coal blending and perfect the old mathematical model of steam coal blending.
Preservice Mathematics Teachers' Perceptions of Drama Based Instruction
Bulut, Neslihan
2016-01-01
The purpose of this study was to determine the perceptions of pre-service mathematics teachers related to drama-based instruction. For this purpose, effects of a drama-based mathematics course on senior class pre-service mathematics teachers' knowledge about drama-based instruction and teacher candidates' competencies for developing and…
Mathematical analysis of a muscle architecture model.
Navallas, Javier; Malanda, Armando; Gila, Luis; Rodríguez, Javier; Rodríguez, Ignacio
2009-01-01
Modeling of muscle architecture, which aims to recreate mathematically the physiological structure of the muscle fibers and motor units, is a powerful tool for understanding and modeling the mechanical and electrical behavior of the muscle. Most of the published models are presented in the form of algorithms, without mathematical analysis of mechanisms or outcomes of the model. Through the study of the muscle architecture model proposed by Stashuk, we present the analytical tools needed to better understand these models. We provide a statistical description for the spatial relations between motor units and muscle fibers. We are particularly concerned with two physiological quantities: the motor unit fiber number, which we expect to be proportional to the motor unit territory area; and the motor unit fiber density, which we expect to be constant for all motor units. Our results indicate that the Stashuk model is in good agreement with the physiological evidence in terms of the expectations outlined above. However, the resulting variance is very high. In addition, a considerable 'edge effect' is present in the outer zone of the muscle cross-section, making the properties of the motor units dependent on their location. This effect is relevant when motor unit territories and muscle cross-section are of similar size.
Affinity and Hostility in Divided Communities: a Mathematical Model
Thron, Christopher
2015-01-01
We propose, develop, and analyze a mathematical model of intergroup attitudes in a community that is divided between two distinct social groups (which may be distinguished by religion, ethnicity, or some other socially distinguishing factor). The model is based on very simple premises that are both intuitive and justified by sociological research. We investigate the behavior of the model in various special cases, for various model configurations. We discuss the stability of the model, and the continuous or discontinuous dependence of model behavior on various parameters. Finally, we discuss possible implications for strategies to improve intergroup affinity, and to defuse tension and prevent deterioration of intergroup relationships.
Laser filamentation mathematical methods and models
Lorin, Emmanuel; Moloney, Jerome
2016-01-01
This book is focused on the nonlinear theoretical and mathematical problems associated with ultrafast intense laser pulse propagation in gases and in particular, in air. With the aim of understanding the physics of filamentation in gases, solids, the atmosphere, and even biological tissue, specialists in nonlinear optics and filamentation from both physics and mathematics attempt to rigorously derive and analyze relevant non-perturbative models. Modern laser technology allows the generation of ultrafast (few cycle) laser pulses, with intensities exceeding the internal electric field in atoms and molecules (E=5x109 V/cm or intensity I = 3.5 x 1016 Watts/cm2 ). The interaction of such pulses with atoms and molecules leads to new, highly nonlinear nonperturbative regimes, where new physical phenomena, such as High Harmonic Generation (HHG), occur, and from which the shortest (attosecond - the natural time scale of the electron) pulses have been created. One of the major experimental discoveries in this nonlinear...
MATHEMATICAL MODEL OF RIVER BED CHANGE DOWNSTREAM OF XIAOLANGDI RESERVOIR
Institute of Scientific and Technical Information of China (English)
无
2002-01-01
A mathematical model of river bed change downstream of the Xiaolangdi Reservoir was developed based on the most recent achievement of sediment theory in the Yellow River. The model was verified by the comparison of computed results and measured data from 1986 to 1996. Numerical prediction of the erosion and deposition downstream of the Xiaolangdi Reservoir in its first operation year was carried out, and a series of suggestions were given for reservoir operation mode in its early operation period.
Mathematical models of human african trypanosomiasis epidemiology.
Rock, Kat S; Stone, Chris M; Hastings, Ian M; Keeling, Matt J; Torr, Steve J; Chitnis, Nakul
2015-03-01
Human African trypanosomiasis (HAT), commonly called sleeping sickness, is caused by Trypanosoma spp. and transmitted by tsetse flies (Glossina spp.). HAT is usually fatal if untreated and transmission occurs in foci across sub-Saharan Africa. Mathematical modelling of HAT began in the 1980s with extensions of the Ross-Macdonald malaria model and has since consisted, with a few exceptions, of similar deterministic compartmental models. These models have captured the main features of HAT epidemiology and provided insight on the effectiveness of the two main control interventions (treatment of humans and tsetse fly control) in eliminating transmission. However, most existing models have overestimated prevalence of infection and ignored transient dynamics. There is a need for properly validated models, evolving with improved data collection, that can provide quantitative predictions to help guide control and elimination strategies for HAT.
The mathematical modeling revolution in extractive metallurgy
Szekely, Julian
1988-08-01
A brief review is presented of the current state of extractive metallurgy, and it is shown that it is still a significant part of the national economy. Then a definition is given of mathematical models, and the general philosophy of modeling is discussed, together with the cost of models, hardware, and software options. Several illustrative examples are given, drawn from aluminum electrolysis, flash smelting, tundish operations, and plasma systems. The paper is concluded with the future modeling tasks facing us; these include the more widespread applications of models to represent both existing and new processing operations. It is stressed that models can play a major role in developing a holistic approach to metals and materials processing, where the primary extraction and refining operations are combined with the final processing steps.
Mathematical Modelling of Tyndall Star Initiation
Harvey, Peter; Katz, Richard F; Lacey, Andrew A
2015-01-01
The superheating that usually occurs when a solid is melted by volumetric heating can produce irregular solid/liquid interfaces. Such interfaces can be visualised in ice, where they are sometimes known as Tyndall stars. This paper describes some of the experimental observations of Tyndall stars and a mathematical model for the early stages of their evolution. The modelling is complicated by the strong crystalline anisotropy, which results in an anisotropic kinetic undercooling at the interface, and it leads to an interesting class of codimension-2 free boundary problems.
Mathematical Model of the Processoof Pearlite Austenitization
Directory of Open Access Journals (Sweden)
Olejarczyk-Wożeńska I.
2014-10-01
Full Text Available The paper presents a mathematical model of the pearlite - austenite transformation. The description of this process uses the diffusion mechanism which takes place between the plates of ferrite and cementite (pearlite as well as austenite. The process of austenite growth was described by means of a system of differential equations solved with the use of the finite difference method. The developed model was implemented in the environment of Delphi 4. The proprietary program allows for the calculation of the rate and time of the transformation at an assumed temperature as well as to determine the TTT diagram for the assigned temperature range.
A mathematical model of 'Pride and Prejudice'.
Rinaldi, Sergio; Rossa, Fabio Della; Landi, Pietro
2014-04-01
A mathematical model is proposed for interpreting the love story between Elizabeth and Darcy portrayed by Jane Austen in the popular novel Pride and Prejudice. The analysis shows that the story is characterized by a sudden explosion of sentimental involvements, revealed by the existence of a saddle-node bifurcation in the model. The paper is interesting not only because it deals for the first time with catastrophic bifurcations in romantic relation-ships, but also because it enriches the list of examples in which love stories are described through ordinary differential equations.
A mathematical model of aerosol holding chambers
DEFF Research Database (Denmark)
Zak, M; Madsen, J; Berg, E
1999-01-01
A mathematical model of aerosol delivery from holding chambers (spacers) was developed incorporating tidal volume (VT), chamber volume (Vch), apparatus dead space (VD), effect of valve insufficiency and other leaks, loss of aerosol by immediate impact on the chamber wall, and fallout of aerosol...... in the chamber with time. Four different spacers were connected via filters to a mechanical lung model, and aerosol delivery during "breathing" was determined from drug recovery from the filters. The formula correctly predicted the delivery of budesonide aerosol from the AeroChamber (Trudell Medical, London...
Mathematical methods and models in composites
Mantic, Vladislav
2014-01-01
This book provides a representative selection of the most relevant, innovative, and useful mathematical methods and models applied to the analysis and characterization of composites and their behaviour on micro-, meso-, and macroscale. It establishes the fundamentals for meaningful and accurate theoretical and computer modelling of these materials in the future. Although the book is primarily concerned with fibre-reinforced composites, which have ever-increasing applications in fields such as aerospace, many of the results presented can be applied to other kinds of composites. The topics cover
Mathematical Modelling of Immune Response in Tissues
Directory of Open Access Journals (Sweden)
B. Su
2009-01-01
Full Text Available We have developed a spatial–temporal mathematical model (PDE to capture fundamental aspects of the immune response to antigen. We have considered terms that broadly describe intercellular communication, cell movement, and effector function (activation or inhibition. The PDE model is robust to variation in antigen load and it can account for (1 antigen recognition, (2 an innate immune response, (3 an adaptive immune response, (4 the elimination of antigen and subsequent resolution of the immune response or (5 equilibrium of the immune response to the presence of persistent antigen (chronic infection and the formation of a granuloma.
MATHEMATICAL MODEL OF THE MICROBIAL FLOODING
Institute of Scientific and Technical Information of China (English)
Lei Guang-lun; Zhang Zhong-zhi; Chen Yue-ming
2003-01-01
On the basis of growth kinetics of microorganism and the principle of material balance, equations were derived to describe microbial growth, nutrient consumption, metabolites production and their transport in formation. The changes in porosity, permeability, oil viscosity and capillary force were also described as the main facturs of microbial flooding. For reservoirs with black oil properties, three-dimensional three-phase mathematical models with the cosidaration of multi-microbial components were established to depict microbial flooding oil. With this model, calculated results are in good agreement with experimental data.
Directory of Open Access Journals (Sweden)
Dewi Herawaty
2016-10-01
Full Text Available This research aims at: 1 the influence of the implementation of the model of teaching mathematics realistic based on cognitive conflict students to the ability to understanding the concept and troubleshooting capabilities; 2 determine the larger capacity of the understanding of the concept through the implementation of the model of teaching mathematics realistic based on cognitive conflict junior secondary school students the City of Bengkulu. 3 determine the great improvement of the ability to solve problems through the implementation of the model of teaching mathematics realistic based on cognitive conflict SMP students Bengkulu City.To achieve the goal of this research is to apply Research Design pseudo experiments with research design Pretest-Postest Nonequivalent Control Group Design, with the test instrument the ability to understanding the concept and test the troubleshooting capabilities. The data has been analyzed using the test gains. The results of this research is 1 the ability of understanding the concept and troubleshooting class experiment the given learning with PMR is better than with the ability to understanding the concept and troubleshooting control classes assigned to conventional mathematics lesson; 2 increase the ability of the understanding of the concept through the implementation of the model of teaching mathematics based on cognitive conflict SMP students Bengkulu City is significant with the index gain of 0,755 (high-level; 3 increase the ability to solve problems through the implementation of the model of teaching mathematics based on cognitive conflict SMP students Bengkulu City is significant with the index gain of 0,500 level (is.
Multiscale mathematical modeling and simulation of cellular dynamical process.
Nakaoka, Shinji
2014-01-01
Epidermal homeostasis is maintained by dynamic interactions among molecules and cells at different spatiotemporal scales. Mathematical modeling and simulation is expected to provide clear understanding and precise description of multiscaleness in tissue homeostasis under systems perspective. We introduce a stochastic process-based description of multiscale dynamics. Agent-based modeling as a framework of multiscale modeling to achieve consistent integration of definitive subsystems is proposed. A newly developed algorithm that particularly aims to perform stochastic simulations of cellular dynamical process is introduced. Finally we review applications of multiscale modeling and quantitative study to important aspects of epidermal and epithelial homeostasis.
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Maria eArepeva
2015-04-01
Full Text Available Acquired bacterial resistance is one of the causes of mortality and morbidity from infectious diseases. Mathematical modeling allows us to predict the spread of resistance and to some extent to control its dynamics. The purpose of this review was to examine existing mathematical models in order to understand pros and cons of currently used approaches and to build our own model. During the analysis, seven articles about the mathematical approaches to studying resistance that satisfied the inclusion / exclusion criteria were selected. All models were classified according to the approach used to study resistance in the presence of antibiotic and were analyzed in terms of our research. Some models require modifications associated with the specific of the research. Further work plan of model building is as follows: modify some models, according to our research, check all obtained models on our data, and select the optimal model or several models with the best quality of prediction. After that we would be able to build a model for the development of resistance using the obtained results.
Modelling of and Conjecturing on a Soccer Ball in a Korean Eighth Grade Mathematics Classroom
Lee, Kyeong-Hwa
2011-01-01
The purpose of this article was to describe the task design and implementation of cultural artefacts in a mathematics lesson based on the integration of modelling and conjecturing perspectives. The conceived process of integrating a soccer ball into mathematics lessons via modelling- and conjecturing-based instruction was first detailed. Next, the…
Discipline-Based Remediation: Bridging the Mathematics Gap
Wenner, Jennifer M.; Baer, Eric M.; Burn, Helen E.
2013-10-01
Geoscience relies on numbers, data, equations, graphical representations, and other quantitative skills; therefore, introductory geoscience courses need to accurately portray the science as quantitative [e.g., Wenner et al., 2009]. However, up to 57% of students arrive at college underprepared to perform mathematics at the level necessary to succeed in introductory courses [ACT, 2011]. Although some institutions have turned to prerequisites as a way to ensure appropriate preparation, these extra courses can place undue financial, temporal, and academic burdens on interested students, keeping them from enrolling in science courses that may interest them. As an alternative to mathematics prerequisites, geoscience faculty at the University of Wisconsin Oshkosh and Highline Community College in Des Moines, Wash., funded by the National Science Foundation, developed a model of successful integration of discipline-based mathematics remediation into an introductory geoscience course: The Math You Need, When You Need It (TMYN; http://serc.carleton.edu/mathyouneed/).
Exploring the Relationship between Mathematical Modelling and Classroom Discourse
Redmond, Trevor; Sheehy, Joanne; Brown, Raymond
2010-01-01
This paper explores the notion that the discourse of the mathematics classroom impacts on the practices that students engage when modelling mathematics. Using excerpts of a Year 12 student's report on modelling Newton's law of cooling, this paper argues that when students engage with the discourse of their mathematics classroom in a manner that…
A mathematical model on Acquired Immunodeficiency Syndrome
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Buddhadeo Mahato
2014-10-01
Full Text Available A mathematical model SEIA (susceptible-exposed-infectious-AIDS infected with vertical transmission of AIDS epidemic is formulated. AIDS is one of the largest health problems, the world is currently facing. Even with anti-retroviral therapies (ART, many resource-constrained countries are unable to meet the treatment needs of their infected populations. We consider a function of number of AIDS cases in a community with an inverse relation. A stated theorem with proof and an example to illustrate it, is given to find the equilibrium points of the model. The disease-free equilibrium of the model is investigated by finding next generation matrix and basic reproduction number R0 of the model. The disease-free equilibrium of the AIDS model system is locally asymptotically stable if R0⩽1 and unstable if R0>1. Finally, numerical simulations are presented to illustrate the results.
A mathematical prognosis model for pancreatic cancer patients receiving immunotherapy.
Li, Xuefang; Xu, Jian-Xin
2016-10-07
Pancreatic cancer is one of the most deadly types of cancer since it typically spreads rapidly and can seldom be detected in its early stage. Pancreatic cancer therapy is thus a challenging task, and appropriate prognosis or assessment for pancreatic cancer therapy is of critical importance. In this work, based on available clinical data in Niu et al. (2013) we develop a mathematical prognosis model that can predict the overall survival of pancreatic cancer patients who receive immunotherapy. The mathematical model incorporates pancreatic cancer cells, pancreatic stellate cells, three major classes of immune effector cells CD8+ T cells, natural killer cells, helper T cells, and two major classes of cytokines interleukin-2 (IL-2) and interferon-γ (IFN-γ). The proposed model describes the dynamic interaction between tumor and immune cells. In order for the model to be able to generate appropriate prognostic results for disease progression, the distribution and stability properties of equilibria in the mathematical model are computed and analysed in absence of treatments. In addition, numerical simulations for disease progression with or without treatments are performed. It turns out that the median overall survival associated with CIK immunotherapy is prolonged from 7 to 13months compared with the survival without treatment, this is consistent with the clinical data observed in Niu et al. (2013). The validity of the proposed mathematical prognosis model is thus verified. Our study confirms that immunotherapy offers a better prognosis for pancreatic cancer patients. As a direct extension of this work, various new therapy methods that are under exploration and clinical trials could be assessed or evaluated using the newly developed mathematical prognosis model.
Mathematical Viscosity Models for Ternary Metallic and Silicate Melts
Institute of Scientific and Technical Information of China (English)
FU Yuan-kun; MENG Xian-min; GUO Han-jie
2004-01-01
The mathematical viscosity models for metallic melts were discussed. The experimental data of Ag-Au-Cu systems were used to verify the models based on Chou's general geometric thermodynamic model and the calculated results are consistent with the reported experimental data. A new model predicting the viscosity of multi-component silicate melts was established. The CaO-MnO-SiO2, CaO-FeO-SiO2 and FeO-MnO-SiO2 silicate slag systems were used to verify the model.
Directory of Open Access Journals (Sweden)
Orekhov Vyacheslav Valentinovich
Full Text Available The interaction process of a power plant building with the soil base is studied basing on mathematical modeling of the construction process of Kambarata-2 HPP, taking into account the excavation of foundation pit, the concreting schedule of the building construction, the HPP units putting into operation and territory planning. Mathematical modeling of stress-strain state of the system “power plant - soil base” in the process of construction was performed by using the computer program “Zemlya” (the Earth, which implements the method of finite elements. Such a behavior of soil was described using elastoplastic soil model, the parameters of which were determined from the results of the triaxial tests. As shown by the results of the research, the continuous change of settlement, slope, deflection and torsion of the bottom plate and accordingly change of stressed-strained state of power plant are noted during the construction process. The installed HPP construction schedule, starting from the construction of the first block and the adjacent mounting platform, is leading to the formation of initial roll of bottom plate to the path of the mounting pad. In the process of further construction of powerhouse, up to the 29th phase of construction (out of 40, a steady increase in its subsidence (maximum values of about 4.5 cm is noted. Filling of foundation pit hollows and territorial planning of the construction area lead to drastic situation. In this case, as a territory planning points exceeded the relief, the plastic deformation in the soil evolves, resulting in significant subsidence of the bottom plate under the first block (up to 7.4 cm. As a result, the additional subsidence of the soil of bottom plate edges lead to the large vertical movement in relation to its central part and it is bent around the X axis, resulting in a large horizontal tensile stress values of Sz (up to 2.17 MPa in the constructive elements of the upper part of the
Santos, Guido; Díaz, Mario; Torres, Néstor V
2016-01-01
A connection between lipid rafts and Alzheimer's disease has been studied during the last decades. Mathematical modeling approaches have recently been used to correlate the effects of lipid composition changes in the physicochemical properties of raft-like membranes. Here we propose an agent based model to assess the effect of lipid changes in lipid rafts on the evolution and progression of Alzheimer's disease using lipid profile data obtained in an established model of familial Alzheimer's disease. We have observed that lipid raft size and lipid mobility in non-raft domains are two main factors that increase during age and are accelerated in the transgenic Alzheimer's disease mouse model. The consequences of these changes are discussed in the context of neurotoxic amyloid β production. Our agent based model predicts that increasing sterols (mainly cholesterol) and long-chain polyunsaturated fatty acids (LCPUFA) (mainly DHA, docosahexaenoic acid) proportions in the membrane composition might delay the onset and progression of the disease.
Mathematical modeling of brain tumors: effects of radiotherapy and chemotherapy
Energy Technology Data Exchange (ETDEWEB)
Powathil, G [Department of Applied Mathematics, University of Waterloo, Waterloo, Ontario, N2L 3G1 (Canada); Kohandel, M [Department of Applied Mathematics, University of Waterloo, Waterloo, Ontario, N2L 3G1 (Canada); Sivaloganathan, S [Department of Applied Mathematics, University of Waterloo, Waterloo, Ontario, N2L 3G1 (Canada); Oza, A [Center for Mathematical Medicine, Fields Institute for Research in Mathematical Sciences, Toronto, Ontario M5T 3J1 (Canada); Milosevic, M [Radiation Medicine Program, Princess Margaret Hospital, and Department of Radiation Oncology, University of Toronto, Toronto, Ontario M5G 2M9 (Canada)
2007-06-07
Gliomas, the most common primary brain tumors, are diffusive and highly invasive. The standard treatment for brain tumors consists of a combination of surgery, radiation therapy and chemotherapy. Over the past few years, mathematical models have been applied to study untreated and treated brain tumors. In an effort to improve treatment strategies, we consider a simple spatio-temporal mathematical model, based on proliferation and diffusion, that incorporates the effects of radiotherapeutic and chemotherapeutic treatments. We study the effects of different schedules of radiation therapy, including fractionated and hyperfractionated external beam radiotherapy, using a generalized linear quadratic (LQ) model. The results are compared with published clinical data. We also discuss the results for combination therapy (radiotherapy plus temozolomide, a new chemotherapy agent), as proposed in recent clinical trials. We use the model to predict optimal sequencing of the postoperative (combination of radiotherapy and adjuvant, neo-adjuvant or concurrent chemotherapy) treatments for brain tumors.
Sullivan, A L
2007-01-01
In recent years, advances in computational power and spatial data analysis (GIS, remote sensing, etc) have led to an increase in attempts to model the spread and behvaiour of wildland fires across the landscape. This series of review papers endeavours to critically and comprehensively review all types of surface fire spread models developed since 1990. This paper reviews models of a simulation or mathematical analogue nature. Most simulation models are implementations of existing empirical or quasi-empirical models and their primary function is to convert these generally one dimensional models to two dimensions and then propagate a fire perimeter across a modelled landscape. Mathematical analogue models are those that are based on some mathematical conceit (rather than a physical representation of fire spread) that coincidentally simulates the spread of fire. Other papers in the series review models of an physical or quasi-physical nature and empirical or quasi-empirical nature. Many models are extensions or ...
Solar Panel Mathematical Modeling Using Simulink
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Chandani Sharma
2014-05-01
Full Text Available For decades, electricity is a key driver of socio-economy development. Nowadays, in the context of competition there is a direct relationship between electricity generation and sustainable development of the country. This paper presents distinct use of a Photovoltaic array offering great potential as source of electricity. The simulation uses One-diode equivalent circuit in order to investigate I-V and P-V characteristics. The GUI model is designed with Simulink block libraries. The goals of proposed model are to perform a systematic analysis, modeling and evaluation of the key subsystems for obtaining Maximum Power Point of a solar cell. Effect of increasing number of cells is described at Standard Test Conditions by mathematical modeling of equations. It is desirable to achieve maximum power output at a minimum cost under various operating conditions. Index Terms—
Chen, Emile P; Chen, Liangfu; Ji, Yan; Tai, Guoying; Wen, Yuan H; Ellens, Harma
2010-12-01
β-Naphthoflavone (BNF) is a synthetic flavone that selectively and potently induces CYP1A enzymes via aryl hydrocarbon receptor activation. Mechanism-based mathematical models of CYP1A enzyme induction were developed to predict the time course of enzyme induction and quantitatively evaluate the interrelationship between BNF plasma concentrations, hepatic CYP1A1 and CYP1A2 mRNA levels, and CYP1A enzyme activity in rats in vivo. Male Sprague-Dawley rats received a continuous intravenous infusion of vehicle or 1.5 or 6 mg · kg(-1) · h(-1) BNF for 6 h, with blood and liver sampling. Plasma BNF concentrations were determined by liquid chromatography-tandem mass spectrometry. Hepatic mRNA levels of CYP1A1 and CYP1A2 were determined by TaqMan. Ethoxyresorufin O-deethylation was used to measure the increase in CYP1A enzyme activity as a result of induction. The induction of hepatic CYP1A1/CYP1A2 mRNA and CYP1A activity occurred within 2 h after BNF administration. This caused a rapid increase in metabolic clearance of BNF, resulting in plasma concentrations declining during the infusion. Overall, the enzyme induction models developed in this study adequately captured the time course of BNF pharmacokinetics, CYP1A1/CYP1A2 mRNA levels, and increases in CYP1A enzyme activity data for both dose groups simultaneously. The model-predicted degradation half-life of CYP1A enzyme activity is comparable with previously reported values. The present results also confirm a previous in vitro finding that CYP1A1 is the predominant contributor to CYP1A induction. These physiologically based models provide a basis for predicting drug-induced toxicity in humans from in vitro and preclinical data and can be a valuable tool in drug development.
Mathematics of tsunami: modelling and identification
Krivorotko, Olga; Kabanikhin, Sergey
2015-04-01
Tsunami (long waves in the deep water) motion caused by underwater earthquakes is described by shallow water equations ( { ηtt = div (gH (x,y)-gradη), (x,y) ∈ Ω, t ∈ (0,T ); η|t=0 = q(x,y), ηt|t=0 = 0, (x,y) ∈ Ω. ( (1) Bottom relief H(x,y) characteristics and the initial perturbation data (a tsunami source q(x,y)) are required for the direct simulation of tsunamis. The main difficulty problem of tsunami modelling is a very big size of the computational domain (Ω = 500 × 1000 kilometres in space and about one hour computational time T for one meter of initial perturbation amplitude max|q|). The calculation of the function η(x,y,t) of three variables in Ω × (0,T) requires large computing resources. We construct a new algorithm to solve numerically the problem of determining the moving tsunami wave height S(x,y) which is based on kinematic-type approach and analytical representation of fundamental solution. Proposed algorithm of determining the function of two variables S(x,y) reduces the number of operations in 1.5 times than solving problem (1). If all functions does not depend on the variable y (one dimensional case), then the moving tsunami wave height satisfies of the well-known Airy-Green formula: S(x) = S(0)° --- 4H (0)/H (x). The problem of identification parameters of a tsunami source using additional measurements of a passing wave is called inverse tsunami problem. We investigate two different inverse problems of determining a tsunami source q(x,y) using two different additional data: Deep-ocean Assessment and Reporting of Tsunamis (DART) measurements and satellite altimeters wave-form images. These problems are severely ill-posed. The main idea consists of combination of two measured data to reconstruct the source parameters. We apply regularization techniques to control the degree of ill-posedness such as Fourier expansion, truncated singular value decomposition, numerical regularization. The algorithm of selecting the truncated number of
Mathematical modelling of risk reduction in reinsurance
Balashov, R. B.; Kryanev, A. V.; Sliva, D. E.
2017-01-01
The paper presents a mathematical model of efficient portfolio formation in the reinsurance markets. The presented approach provides the optimal ratio between the expected value of return and the risk of yield values below a certain level. The uncertainty in the return values is conditioned by use of expert evaluations and preliminary calculations, which result in expected return values and the corresponding risk levels. The proposed method allows for implementation of computationally simple schemes and algorithms for numerical calculation of the numerical structure of the efficient portfolios of reinsurance contracts of a given insurance company.
Mathematical Modeling of Diaphragm Pneumatic Motors
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Fojtášek Kamil
2014-03-01
Full Text Available Pneumatic diaphragm motors belong to the group of motors with elastic working parts. This part is usually made of rubber with a textile insert and it is deformed under the pressure of a compressed air or from the external mass load. This is resulting in a final working effect. In this type of motors are in contact two different elastic environments – the compressed air and the esaltic part. These motors are mainly the low-stroke and working with relatively large forces. This paper presents mathematical modeling static properties of diaphragm motors.
Mathematical modeling of diesel fuel hydrotreating
Tataurshikov, A.; Ivanchina, E.; Krivtcova, N.; Krivtsov, E.; Syskina, A.
2015-11-01
Hydrotreating of the diesel fraction with the high initial sulfur content of 1,4 mass% is carried out in the flow-through laboratory setup with the industrial GKD-202 catalyst at various process temperature. On the basis of the experimental data the regularities of the hydrogenation reactions are revealed, and the formalized scheme of sulfur-containing components (sulfides, benzothiophenes, and dibenzothiophenes) transformations is made. The mathematical model of hydrotreating process is developed, the constant values for the reaction rate of hydrodesulfurization of the specified components are calculated.
Mathematical modeling of tornadoes and squall storms
Directory of Open Access Journals (Sweden)
Sergey A. Arsen’yev
2011-04-01
Full Text Available Recent advances in modeling of tornadoes and twisters consist of significant achievements in mathematical calculation of occurrence and evolution of a violent F5-class tornado on the Fujita scale, and four-dimensional mathematical modeling of a tornado with the fourth coordinate time multiplied by its characteristic velocity. Such a tornado can arise in a thunderstorm supercell filled with turbulent whirlwinds. A theory of the squall storms is proposed. The squall storm is modeled by running perturbation of the temperature inversion on the lower boundary of cloudiness. This perturbation is induced by the action of strong, hurricane winds in the upper and middle troposphere, and looks like a running solitary wave (soliton; which is developed also in a field of pressure and velocity of a wind. If a soliton of a squall storm gets into the thunderstorm supercell then this soliton is captured by supercell. It leads to additional pressure fall of air inside a storm supercell and stimulate amplification of wind velocity here. As a result, a cyclostrophic balance inside a storm supercell generates a tornado. Comparison of the radial distribution of wind velocity inside a tornado calculated by using the new formulas and equations with radar observations of the wind velocity inside Texas Tornado Dummit in 1995 and inside the 3 May 1999 Oklahoma City Tornado shows good correspondence.
Three dimensional mathematical model of tooth for finite element analysis
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Puškar Tatjana
2010-01-01
Full Text Available Introduction. The mathematical model of the abutment tooth is the starting point of the finite element analysis of stress and deformation of dental structures. The simplest and easiest way is to form a model according to the literature data of dimensions and morphological characteristics of teeth. Our method is based on forming 3D models using standard geometrical forms (objects in programmes for solid modeling. Objective. Forming the mathematical model of abutment of the second upper premolar for finite element analysis of stress and deformation of dental structures. Methods. The abutment tooth has a form of a complex geometric object. It is suitable for modeling in programs for solid modeling SolidWorks. After analyzing the literature data about the morphological characteristics of teeth, we started the modeling dividing the tooth (complex geometric body into simple geometric bodies (cylinder, cone, pyramid,.... Connecting simple geometric bodies together or substricting bodies from the basic body, we formed complex geometric body, tooth. The model is then transferred into Abaqus, a computational programme for finite element analysis. Transferring the data was done by standard file format for transferring 3D models ACIS SAT. Results. Using the programme for solid modeling SolidWorks, we developed three models of abutment of the second maxillary premolar: the model of the intact abutment, the model of the endodontically treated tooth with two remaining cavity walls and the model of the endodontically treated tooth with two remaining walls and inserted post. Conclusion Mathematical models of the abutment made according to the literature data are very similar with the real abutment and the simplifications are minimal. These models enable calculations of stress and deformation of the dental structures. The finite element analysis provides useful information in understanding biomechanical problems and gives guidance for clinical research.
Comparison of Different Mathematical Models of Cavitation
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Dorota HOMA
2014-12-01
Full Text Available Cavitation occurs during the flow when local pressure drops to the saturation pressure according to the temperature of the flow. It includes both evaporation and condensation of the vapor bubbles, which occur alternately with high frequency. Cavitation can be very dangerous, especially for pumps, because it leads to break of flow continuity, noise, vibration, erosion of blades and change in pump’s characteristics. Therefore it is very important for pump designers and users to avoid working in cavitation conditions. Simulation of flow can be very useful in that and can indicate if there is risk of cavitating flow occurrence. As this is a multiphase flow and quite complicated phenomena, there are a few mathematical models describing it. The aim of this paper is to make a short review of them and describe their approach to model cavitation. It is desirable to know differences between them to model this phenomenon properly.
A MATHEMATICAL MODEL OF RESERVOIR SEDIMENTATION
Institute of Scientific and Technical Information of China (English)
HUANG Jinchi
2001-01-01
Reliable quantitative estimation of bed aggradation or degradation is important for river-training and water management projects. With the development of water resources, sediment problems associated with a dam are becoming more severe. This paper describes some special problems in mathematical model for calculation of degradation and aggradation in a reservoir. The main efforts of this study are on the treatment of some physical processes of fine sediment transport (＜0.05 mm). Problems in a reservoir are obviously different from a natural stream, such as the turbid current flow, orifice sediment flushing;and the initiation and consolidation of cohesive sediment deposition. The case of Liujiaxia Reservoir,which is located in the upper reaches of the Yellow River, is employed to verify the model. The results show that the model is applicable in the evaluation of an engineering planing with plenty of fine sediment movement.
Mathematical Simulating Model of Phased-Array Antenna in Multifunction Array Radar
Institute of Scientific and Technical Information of China (English)
无
1999-01-01
A mathematical simulating model of phased-array antenna in multifunction array radar has been approached in this paper, including the mathematical simulating model of plane phased-array pattern, the mathematical simulating model of directionality factor, the mathematical simulating model of array factor, the mathematical simulating model of array element factor and the mathematical simulating model of beam steering.
Mathematical modeling of the Phoenix Rising pathway.
Directory of Open Access Journals (Sweden)
Chad Liu
2014-02-01
Full Text Available Apoptosis is a tightly controlled process in mammalian cells. It is important for embryogenesis, tissue homoeostasis, and cancer treatment. Apoptosis not only induces cell death, but also leads to the release of signals that promote rapid proliferation of surrounding cells through the Phoenix Rising (PR pathway. To quantitatively understand the kinetics of interactions of different molecules in this pathway, we developed a mathematical model to simulate the effects of various changes in the PR pathway on the secretion of prostaglandin E2 (PGE2, a key factor for promoting cell proliferation. These changes include activation of caspase 3 (C3, caspase 7 (C7, and nuclear factor κB (NFκB. In addition, we simulated the effects of cyclooxygenase-2 (COX2 inhibition and C3 knockout on the level of secreted PGE2. The model predictions on PGE2 in MEF and 4T1 cells at 48 hours after 10-Gray radiation were quantitatively consistent with the experimental data in the literature. Compared to C7, the model predicted that C3 activation was more critical for PGE2 production. The model also predicted that PGE2 production could be significantly reduced when COX2 expression was blocked via either NFκB inactivation or treatment of cells with exogenous COX2 inhibitors, which led to a decrease in the rate of conversion from arachidonic acid to prostaglandin H2 in the PR pathway. In conclusion, the mathematical model developed in this study yielded new insights into the process of tissue regrowth stimulated by signals from apoptotic cells. In future studies, the model can be used for experimental data analysis and assisting development of novel strategies/drugs for improving cancer treatment or normal tissue regeneration.
Preparing Secondary Mathematics Teachers: A Focus on Modeling in Algebra
Jung, Hyunyi; Mintos, Alexia; Newton, Jill
2015-01-01
This study addressed the opportunities to learn (OTL) modeling in algebra provided to secondary mathematics pre-service teachers (PSTs). To investigate these OTL, we interviewed five instructors of required mathematics and mathematics education courses that had the potential to include opportunities for PSTs to learn algebra at three universities.…
Building Mathematics Achievement Models in Four Countries Using TIMSS 2003
Wang, Ze; Osterlind, Steven J.; Bergin, David A.
2012-01-01
Using the Trends in International Mathematics and Science Study 2003 data, this study built mathematics achievement models of 8th graders in four countries: the USA, Russia, Singapore and South Africa. These 4 countries represent the full spectrum of mathematics achievement. In addition, they represent 4 continents, and they include 2 countries…
Mathematical modeling of sediment transport jn estuaries and coastal regions
Institute of Scientific and Technical Information of China (English)
窦国仁; 董凤舞; 窦希萍; 李禔来
1995-01-01
Based on the suspended sediment transport equation and transport capacity formula under the action of tidal currents and wind waves, a horizontal 2-D mathematical model of suspended sediment transport for estuaries and coastal regions is established. The verification of calculations shows that the sediment concentration distribution and sea bed deformation in the estuaries and coastal regions can be successfully simulated. Therefore, a new method for studying and solving the sediment problems in the estuarine and coastal engineering is presented.
Mathematical Model of the Jet Engine Fuel System
Klimko, Marek
2015-05-01
The paper discusses the design of a simplified mathematical model of the jet (turbo-compressor) engine fuel system. The solution will be based on the regulation law, where the control parameter is a fuel mass flow rate and the regulated parameter is the rotational speed. A differential equation of the jet engine and also differential equations of other fuel system components (fuel pump, throttle valve, pressure regulator) will be described, with respect to advanced predetermined simplifications.
Mathematical Model of the Jet Engine Fuel System
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Klimko Marek
2015-01-01
Full Text Available The paper discusses the design of a simplified mathematical model of the jet (turbo-compressor engine fuel system. The solution will be based on the regulation law, where the control parameter is a fuel mass flow rate and the regulated parameter is the rotational speed. A differential equation of the jet engine and also differential equations of other fuel system components (fuel pump, throttle valve, pressure regulator will be described, with respect to advanced predetermined simplifications.
Building a Two Axes Process Model of Understanding Mathematics
Koyama, Masataka
1993-01-01
The purpose of this study is to make clear what kind of characteristics a model of understanding mathematics should have so as to be useful and effective in mathematics education. The models of understanding presented in preceding papers are classified into two large categories, i. e. "aspect model" and "process model". Focusing on the process of understanding mathematics, reflective thinking plays an important role to develop children's understanding, or to progress children's thinking from ...
A novel mathematical model for controllable near-field electrospinning
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Changhai Ru
2014-01-01
Full Text Available Near-field electrospinning (NFES had better controllability than conventional electrospinning. However, due to the lack of guidance of theoretical model, precise deposition of micro/nano fibers could only accomplished by experience. To analyze the behavior of charged jet in NFES using mathematical model, the momentum balance equation was simplified and a new expression between jet cross-sectional radius and axial position was derived. Using this new expression and mass conservation equation, expressions for jet cross-sectional radius and velocity were derived in terms of axial position and initial jet acceleration in the form of exponential functions. Based on Slender-body theory and Giesekus model, a quadratic equation for initial jet acceleration was acquired. With the proposed model, it was able to accurately predict the diameter and velocity of polymer fibers in NFES, and mathematical analysis rather than experimental methods could be applied to study the effects of the process parameters in NFES. Moreover, the movement velocity of the collector stage can be regulated by mathematical model rather than experience. Therefore, the model proposed in this paper had important guiding significance to precise deposition of polymer fibers.
A novel mathematical model for controllable near-field electrospinning
Energy Technology Data Exchange (ETDEWEB)
Ru, Changhai, E-mail: rchhai@gmail.com, E-mail: luojun@shu.edu.cn [College of Automation, Harbin Engineering University, Harbin 150001 (China); Robotics and Microsystems Center, Soochow University, Suzhou 215021 (China); Chen, Jie; Shao, Zhushuai [Robotics and Microsystems Center, Soochow University, Suzhou 215021 (China); Pang, Ming [College of Automation, Harbin Engineering University, Harbin 150001 (China); Luo, Jun, E-mail: rchhai@gmail.com, E-mail: luojun@shu.edu.cn [School of Mechatronics Engineering and Automation, Shanghai University, Shanghai 200072 (China)
2014-01-15
Near-field electrospinning (NFES) had better controllability than conventional electrospinning. However, due to the lack of guidance of theoretical model, precise deposition of micro/nano fibers could only accomplished by experience. To analyze the behavior of charged jet in NFES using mathematical model, the momentum balance equation was simplified and a new expression between jet cross-sectional radius and axial position was derived. Using this new expression and mass conservation equation, expressions for jet cross-sectional radius and velocity were derived in terms of axial position and initial jet acceleration in the form of exponential functions. Based on Slender-body theory and Giesekus model, a quadratic equation for initial jet acceleration was acquired. With the proposed model, it was able to accurately predict the diameter and velocity of polymer fibers in NFES, and mathematical analysis rather than experimental methods could be applied to study the effects of the process parameters in NFES. Moreover, the movement velocity of the collector stage can be regulated by mathematical model rather than experience. Therefore, the model proposed in this paper had important guiding significance to precise deposition of polymer fibers.
Mathematical analysis of intermittent gas injection model in oil production
Tasmi, Silvya, D. R.; Pudjo, S.; Leksono, M.; Edy, S.
2016-02-01
Intermittent gas injection is a method to help oil production process. Gas is injected through choke in surface and then gas into tubing. Gas forms three areas in tubing: gas column area, film area and slug area. Gas column is used to propel slug area until surface. A mathematical model of intermittent gas injection is developed in gas column area, film area and slug area. Model is expanding based on mass and momentum conservation. Using assume film thickness constant in tubing, model has been developed by Tasmi et. al. [14]. Model consists of 10 ordinary differential equations. In this paper, assumption of pressure in gas column is uniform. Model consist of 9 ordinary differential equations. Connection of several variables can be obtained from this model. Therefore, dynamics of all variables that affect to intermittent gas lift process can be seen from four equations. To study the behavior of variables can be analyzed numerically and mathematically. In this paper, simple mathematically analysis approach is used to study behavior of the variables. Variables that affect to intermittent gas injection are pressure in upstream valve and in gas column. Pressure in upstream valve will decrease when gas mass in valve greater than gas mass in choke. Dynamic of the pressure in the gas column will decrease and increase depending on pressure in upstream valve.
Ma, Jianlong; Pan, Hui; Zeng, Yan; Lv, Yehui; Zhang, Heng; Xue, Aimin; Jiang, Jieqing; Ma, Kaijun; Chen, Long
2015-12-01
Precise estimation of postmortem interval (PMI) is crucial in some criminal cases. This study aims to find some optimal markers for PMI estimation and build a mathematical model that could be used in various temperature conditions. Different mRNA and microRNA markers in rat brain samples were detected using real-time fluorescent quantitative PCR at 12 time points within 144 h postmortem and at temperatures of 4, 15, 25, and 35 °C. Samples from 36 other rats were used to verify the animal mathematical model. Brain-specific mir-9 and mir-125b are effective endogenous control markers that are not affected by PMI up to 144 h postmortem under these temperatures, whereas the commonly used U6 is not a suitable endogenous control in this study. Among all the candidate markers, ΔCt (β-actin) has the best correlation coefficient with PMI and was used to build a new model using R software which can simultaneously manage both PMI and temperature parameters. This animal mathematical model is verified using samples from 36 other rats and shows increased accuracy for higher temperatures and longer PMI. In this study, β-actin was found to be an optimal marker to estimate PMI and some other markers were found to be suitable to act as endogenous controls. Additionally, we have used R code software to build a model of PMI estimation that could be used in various temperature conditions.
Multiscale mathematical modeling of the hypothalamo-pituitary-gonadal axis.
Clément, Frédérique
2016-07-01
Although the fields of systems and integrative biology are in full expansion, few teams are involved worldwide into the study of reproductive function from the mathematical modeling viewpoint. This may be due to the fact that the reproductive function is not compulsory for individual organism survival, even if it is for species survival. Alternatively, the complexity of reproductive physiology may be discouraging. Indeed, the hypothalamo-pituitary-gonadal (HPG) axis involves not only several organs and tissues but also intricate time (from the neuronal millisecond timescale to circannual rhythmicity) and space (from molecules to organs) scales. Yet, mathematical modeling, and especially multiscale modeling, can renew our approaches of the molecular, cellular, and physiological processes underlying the control of reproductive functions. In turn, the remarkable dynamic features exhibited by the HPG axis raise intriguing and challenging questions to modelers and applied mathematicians. In this article, we draw a panoramic review of some mathematical models designed in the framework of the female HPG, with a special focus on the gonadal and central control of follicular development. On the gonadal side, the modeling of follicular development calls to the generic formalism of structured cell populations, that allows one to make mechanistic links between the control of cell fate (proliferation, differentiation, or apoptosis) and that of the follicle fate (ovulation or degeneration) or to investigate how the functional interactions between the oocyte and its surrounding cells shape the follicle morphogenesis. On the central, mainly hypothalamic side, models based on dynamical systems with multiple timescales allow one to represent within a single framework both the pulsatile and surge patterns of the neurohormone GnRH. Beyond their interest in basic research investigations, mathematical models can also be at the source of useful tools to study the encoding and decoding of
Rudolph, Lee
2012-01-01
In this book Lee Rudolph brings together international contributors who combine psychological and mathematical perspectives to analyse how qualitative mathematics can be used to create models of social and psychological processes. Bridging the gap between the fields with an imaginative and stimulating collection of contributed chapters, the volume updates the current research on the subject, which until now has been rather limited, focussing largely on the use of statistics. Qualitative Mathematics for the Social Sciences contains a variety of useful illustrative figures, in
On the mathematical modeling of memristor, memcapacitor, and meminductor
Radwan, Ahmed G
2015-01-01
This book introduces the basic fundamentals, models, emulators and analyses of mem-elements in the circuit theory with applications. The book starts reviewing the literature on mem-elements, models and their recent applications. It presents mathematical models, numerical results, circuit simulations, and experimental results for double-loop hysteresis behavior of mem-elements. The authors introduce a generalized memristor model in the fractional-order domain under different input and different designs for emulator-based mem-elements, with circuit and experimental results. The basic concept of memristive-based relaxation-oscillators in the circuit theory is also covered. The reader will moreover find in this book information on memristor-based multi-level digital circuits, memristor-based multi-level multiplier and memcapacitor-based oscillators and synaptic circuits.
Mathematical Models and Methods for Living Systems
Chaplain, Mark; Pugliese, Andrea
2016-01-01
The aim of these lecture notes is to give an introduction to several mathematical models and methods that can be used to describe the behaviour of living systems. This emerging field of application intrinsically requires the handling of phenomena occurring at different spatial scales and hence the use of multiscale methods. Modelling and simulating the mechanisms that cells use to move, self-organise and develop in tissues is not only fundamental to an understanding of embryonic development, but is also relevant in tissue engineering and in other environmental and industrial processes involving the growth and homeostasis of biological systems. Growth and organization processes are also important in many tissue degeneration and regeneration processes, such as tumour growth, tissue vascularization, heart and muscle functionality, and cardio-vascular diseases.
Knowledge Map: Mathematical Model and Dynamic Behaviors
Institute of Scientific and Technical Information of China (English)
Hai Zhuge; Xiang-Feng Luo
2005-01-01
Knowledge representation and reasoning is a key issue of the Knowledge Grid. This paper proposes a Knowledge Map (KM) model for representing and reasoning causal knowledge as an overlay in the Knowledge Grid. It extends Fuzzy Cognitive Maps (FCMs) to represent and reason not only simple cause-effect relations, but also time-delay causal relations, conditional probabilistic causal relations and sequential relations. The mathematical model and dynamic behaviors of KM are presented. Experiments show that, under certain conditions, the dynamic behaviors of KM can translate between different states. Knowing this condition, experts can control or modify the constructed KM while its dynamic behaviors do not accord with their expectation. Simulations and applications show that KM is more powerful and natural than FCM in emulating real world.
Mathematics Teacher Education: A Model from Crimea.
Ferrucci, Beverly J.; Evans, Richard C.
1993-01-01
Reports on the mathematics teacher preparation program at Simferopol State University, the largest institution of higher education in the Crimea. The article notes the value of investigating what other countries consider essential in mathematics teacher education to improve the mathematical competence of students in the United States. (SM)
Common Mathematical Model of Fatigue Characteristics
Directory of Open Access Journals (Sweden)
Z. Maléř
2004-01-01
Full Text Available This paper presents a new common mathematical model which is able to describe fatigue characteristics in the whole necessary range by one equation only:log N = A(R + B(R ∙ log Sawhere A(R = AR2 + BR + C and B(R = DR2 + AR + F.This model was verified by five sets of fatigue data taken from the literature and by our own three additional original fatigue sets. The fatigue data usually described the region of N 104 to 3 x 106 and stress ratio of R = -2 to 0.5. In all these cases the proposed model described fatigue results with small scatter. Studying this model, following knowledge was obtained:– the parameter ”stress ratio R” was a good physical characteristic– the proposed model provided a good description of the eight collections of fatigue test results by one equation only– the scatter of the results through the whole scope is only a little greater than that round the individual S/N curve– using this model while testing may reduce the number of test samples and shorten the test time– as the proposed model represents a common form of the S/N curve, it may be used for processing uniform objective fatigue life results, which may enable mutual comparison of fatigue characteristics.
Thermocouple mathematical model research based on PID neural network%基于PID神经网络的热电偶数学模型研究
Institute of Scientific and Technical Information of China (English)
徐宏宇; 朱永丽
2011-01-01
为提高热电偶的测温精度,首先介绍了热电偶测温数据处理的一般情况,在总结对比现有方法的优缺点基础上,对如何选取热电偶标定点的问题进行研究。设计了实际多路电偶数据采集电路,并对采集的数据进行了分析处理,运用PID神经网络建立热电偶的数学模型。通过实验验证,这种方法的测温精度较高,能满足实际对宽范围高精度的温度测量需要。%In order to improve the measurement precision of thermocouple,at first the general temperature data processing procedure which stems from the thermocouple is introduced.On the base of summing up exsiting methods,the problem is studied on how to select the special points of thermocouple.And a system is designed to collecting multichannel temperature data.By means of analysing the data,the mathematical model of thermocouple is founded.Proved by experiments,this method increases the temperature measurement precision and fits to actual request,which is wide rang with high pricise.
Lin, Z; Gehring, R; Mochel, J P; Lavé, T; Riviere, J E
2016-10-01
This review provides a tutorial for individuals interested in quantitative veterinary pharmacology and toxicology and offers a basis for establishing guidelines for physiologically based pharmacokinetic (PBPK) model development and application in veterinary medicine. This is important as the application of PBPK modeling in veterinary medicine has evolved over the past two decades. PBPK models can be used to predict drug tissue residues and withdrawal times in food-producing animals, to estimate chemical concentrations at the site of action and target organ toxicity to aid risk assessment of environmental contaminants and/or drugs in both domestic animals and wildlife, as well as to help design therapeutic regimens for veterinary drugs. This review provides a comprehensive summary of PBPK modeling principles, model development methodology, and the current applications in veterinary medicine, with a focus on predictions of drug tissue residues and withdrawal times in food-producing animals. The advantages and disadvantages of PBPK modeling compared to other pharmacokinetic modeling approaches (i.e., classical compartmental/noncompartmental modeling, nonlinear mixed-effects modeling, and interspecies allometric scaling) are further presented. The review finally discusses contemporary challenges and our perspectives on model documentation, evaluation criteria, quality improvement, and offers solutions to increase model acceptance and applications in veterinary pharmacology and toxicology.
Mathematical programming solver based on local search
Gardi, Frédéric; Darlay, Julien; Estellon, Bertrand; Megel, Romain
2014-01-01
This book covers local search for combinatorial optimization and its extension to mixed-variable optimization. Although not yet understood from the theoretical point of view, local search is the paradigm of choice for tackling large-scale real-life optimization problems. Today's end-users demand interactivity with decision support systems. For optimization software, this means obtaining good-quality solutions quickly. Fast iterative improvement methods, like local search, are suited to satisfying such needs. Here the authors show local search in a new light, in particular presenting a new kind of mathematical programming solver, namely LocalSolver, based on neighborhood search. First, an iconoclast methodology is presented to design and engineer local search algorithms. The authors' concern about industrializing local search approaches is of particular interest for practitioners. This methodology is applied to solve two industrial problems with high economic stakes. Software based on local search induces ex...
Mathematical modelling of the growth of human fetus anatomical structures.
Dudek, Krzysztof; Kędzia, Wojciech; Kędzia, Emilia; Kędzia, Alicja; Derkowski, Wojciech
2016-07-08
The goal of this study was to present a procedure that would enable mathematical analysis of the increase of linear sizes of human anatomical structures, estimate mathematical model parameters and evaluate their adequacy. Section material consisted of 67 foetuses-rectus abdominis muscle and 75 foetuses- biceps femoris muscle. The following methods were incorporated to the study: preparation and anthropologic methods, image digital acquisition, Image J computer system measurements and statistical analysis method. We used an anthropologic method based on age determination with the use of crown-rump length-CRL (V-TUB) by Scammon and Calkins. The choice of mathematical function should be based on a real course of the curve presenting growth of anatomical structure linear size Ύ in subsequent weeks t of pregnancy. Size changes can be described with a segmental-linear model or one-function model with accuracy adequate enough for clinical purposes. The interdependence of size-age is described with many functions. However, the following functions are most often considered: linear, polynomial, spline, logarithmic, power, exponential, power-exponential, log-logistic I and II, Gompertz's I and II and von Bertalanffy's function. With the use of the procedures described above, mathematical models parameters were assessed for V-PL (the total length of body) and CRL body length increases, rectus abdominis total length h, its segments hI, hII, hIII, hIV, as well as biceps femoris length and width of long head (LHL and LHW) and of short head (SHL and SHW). The best adjustments to measurement results were observed in the exponential and Gompertz's models.
Linear models in the mathematics of uncertainty
Mordeson, John N; Clark, Terry D; Pham, Alex; Redmond, Michael A
2013-01-01
The purpose of this book is to present new mathematical techniques for modeling global issues. These mathematical techniques are used to determine linear equations between a dependent variable and one or more independent variables in cases where standard techniques such as linear regression are not suitable. In this book, we examine cases where the number of data points is small (effects of nuclear warfare), where the experiment is not repeatable (the breakup of the former Soviet Union), and where the data is derived from expert opinion (how conservative is a political party). In all these cases the data is difficult to measure and an assumption of randomness and/or statistical validity is questionable. We apply our methods to real world issues in international relations such as nuclear deterrence, smart power, and cooperative threat reduction. We next apply our methods to issues in comparative politics such as successful democratization, quality of life, economic freedom, political stability, and fail...
Modified Mathematical Model For Neutralization System In Stirred Tank Reactor
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Ahmmed Saadi Ibrehem
2011-05-01
Full Text Available A modified model for the neutralization process of Stirred Tank Reactors (CSTR reactor is presented in this study. The model accounts for the effect of strong acid [HCL] flowrate and strong base [NaOH] flowrate with the ionic concentrations of [Cl-] and [Na+] on the Ph of the system. In this work, the effect of important reactor parameters such as ionic concentrations and acid and base flowrates on the dynamic behavior of the CSTR is investigated and the behavior of mathematical model is compared with the reported models for the McAvoy model and Jutila model. Moreover, the results of the model are compared with the experimental data in terms of pH dynamic study. A good agreement is observed between our model prediction and the actual plant data. © 2011 BCREC UNDIP. All rights reserved(Received: 1st March 2011, Revised: 28th March 2011; Accepted: 7th April 2011[How to Cite: A.S. Ibrehem. (2011. Modified Mathematical Model For Neutralization System In Stirred Tank Reactor. Bulletin of Chemical Reaction Engineering & Catalysis, 6(1: 47-52. doi:10.9767/bcrec.6.1.825.47-52][How to Link / DOI: http://dx.doi.org/10.9767/bcrec.6.1.825.47-52 || or local: http://ejournal.undip.ac.id/index.php/bcrec/article/view/825 ] | View in
Mechanical-mathematical modeling for landslide process
Svalova, V.
2009-04-01
500 m and displacement of a landslide in the plan over 1 m. Last serious activization of a landslide has taken place in 2002 with a motion on 53 cm. Catastrophic activization of the deep blockglide landslide in the area of Khoroshevo in Moscow took place in 2006-2007. A crack of 330 m long appeared in the old sliding circus, along which a new 220 m long creeping block was separated from the plateau and began sinking with a displaced surface of the plateau reaching to 12 m. Such activization of the landslide process was not observed in Moscow since mid XIX century. The sliding area of Khoroshevo was stable during long time without manifestations of activity. Revealing of the reasons of deformation and development of ways of protection from deep landslide motions is extremely actual and difficult problem which decision is necessary for preservation of valuable historical monuments and modern city constructions. The reasons of activization and protective measures are discussed. Structure of monitoring system for urban territories is elaborated. Mechanical-mathematical model of high viscous fluid was used for modeling of matter behavior on landslide slopes. Equation of continuity and an approximated equation of the Navier-Stockes for slow motions in a thin layer were used. The results of modelling give possibility to define the place of highest velocity on landslide surface, which could be the best place for monitoring post position. Model can be used for calibration of monitoring equipment and gives possibility to investigate some fundamental aspects of matter movement on landslide slope.
Mathematical modelling of steam generator and design of temperature regulator
Energy Technology Data Exchange (ETDEWEB)
Bogdanovic, S.S. [EE Institute Nikola Tesla, Belgrade (Yugoslavia)
1999-07-01
The paper considers mathematical modelling of once-through power station boiler and numerical algorithm for simulation of the model. Fast and numerically stable algorithm based on the linearisation of model equations and on the simultaneous solving of differential and algebraic equations is proposed. The paper also presents the design of steam temperature regulator by using the method of projective controls. Dynamic behaviour of the system closed with optimal linear quadratic regulator is taken as the reference system. The desired proprieties of the reference system are retained and solutions for superheated steam temperature regulator are determined. (author)
Mathematical Modeling of Contact Resistance in Silicon Photovoltaic Cells
Black, J. P.
2013-10-22
In screen-printed silicon-crystalline solar cells, the contact resistance of a thin interfacial glass layer between the silicon and the silver electrode plays a limiting role for electron transport. We analyze a simple model for electron transport across this layer, based on the driftdiffusion equations. We utilize the size of the current/Debye length to conduct asymptotic techniques to simplify the model; we solve the model numerically to find that the effective contact resistance may be a monotonic increasing, monotonic decreasing, or nonmonotonic function of the electron flux, depending on the values of the physical parameters. © 2013 Society for Industrial and Applied Mathematics.
The use of mathematical models in teaching wastewater treatment engineering
DEFF Research Database (Denmark)
Morgenroth, Eberhard Friedrich; Arvin, Erik; Vanrolleghem, P.
2002-01-01
Mathematical modeling of wastewater treatment processes has become increasingly popular in recent years. To prepare students for their future careers, environmental engineering education should provide students with sufficient background and experiences to understand and apply mathematical models...... efficiently and responsibly. Approaches for introducing mathematical modeling into courses on wastewater treatment engineering are discussed depending on the learning objectives, level of the course and the time available....
Mathematical problems in modeling artificial heart
Directory of Open Access Journals (Sweden)
Ahmed N. U.
1995-01-01
Full Text Available In this paper we discuss some problems arising in mathematical modeling of artificial hearts. The hydrodynamics of blood flow in an artificial heart chamber is governed by the Navier-Stokes equation, coupled with an equation of hyperbolic type subject to moving boundary conditions. The flow is induced by the motion of a diaphragm (membrane inside the heart chamber attached to a part of the boundary and driven by a compressor (pusher plate. On one side of the diaphragm is the blood and on the other side is the compressor fluid. For a complete mathematical model it is necessary to write the equation of motion of the diaphragm and all the dynamic couplings that exist between its position, velocity and the blood flow in the heart chamber. This gives rise to a system of coupled nonlinear partial differential equations; the Navier-Stokes equation being of parabolic type and the equation for the membrane being of hyperbolic type. The system is completed by introducing all the necessary static and dynamic boundary conditions. The ultimate objective is to control the flow pattern so as to minimize hemolysis (damage to red blood cells by optimal choice of geometry, and by optimal control of the membrane for a given geometry. The other clinical problems, such as compatibility of the material used in the construction of the heart chamber, and the membrane, are not considered in this paper. Also the dynamics of the valve is not considered here, though it is also an important element in the overall design of an artificial heart. We hope to model the valve dynamics in later paper.
Mathematical modeling and numerical simulation of Czochralski Crystal Growth
Energy Technology Data Exchange (ETDEWEB)
Jaervinen, J.; Nieminen, R. [Center for Scientific Computing, Espoo (Finland)
1996-12-31
A detailed mathematical model and numerical simulation tools based on the SUPG Finite Element Method for the Czochralski crystal growth has been developed. In this presentation the mathematical modeling and numerical simulation of the melt flow and the temperature distribution in a rotationally symmetric crystal growth environment is investigated. The temperature distribution and the position of the free boundary between the solid and liquid phases are solved by using the Enthalpy method. Heat inside of the Czochralski furnace is transferred by radiation, conduction and convection. The melt flow is governed by the incompressible Navier-Stokes equations coupled with the enthalpy equation. The melt flow is numerically demonstrated and the temperature distribution in the whole Czochralski furnace. (author)
A Mathematical Model of Cigarette Smoldering Process
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Chen P
2014-12-01
Full Text Available A mathematical model for a smoldering cigarette has been proposed. In the analysis of the cigarette combustion and pyrolysis processes, a receding burning front is defined, which has a constant temperature (~450 °C and divides the cigarette into two zones, the burning zone and the pyrolysis zone. The char combustion processes in the burning zone and the pyrolysis of virgin tobacco and evaporation of water in the pyrolysis zone are included in the model. The hot gases flow from the burning zone, are assumed to go out as sidestream smoke during smoldering. The internal heat transport is characterized by effective thermal conductivities in each zone. Thermal conduction of cigarette paper and convective and radiative heat transfer at the outer surface were also considered. The governing partial differential equations were solved using an integral method. Model predictions of smoldering speed as well as temperature and density profiles in the pyrolysis zone for different kinds of cigarettes were found to agree with the experimental data. The model also predicts the coal length and the maximum coal temperatures during smoldering conditions. The model provides a relatively fast and efficient way to simulate the cigarette burning processes. It offers a practical tool for exploring important parameters for cigarette smoldering processes, such as tobacco components, properties of cigarette paper, and heat generation in the burning zone and its dependence on the mass burn rate.
Mathematical Model of Asynchronous Machine in MATLAB Simulink
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A A Ansari
2010-05-01
Full Text Available Different mathematical models have been used over the years to examine different problems associated with induction motors. These range from the simple equivalent circuit models to more complex d,q models and abc models which allow the inclusion of various forms of impedance and/or voltage unbalance. Recently, hybrid models have been developed which allow the inclusion of supply side unbalance but with the computational economy of the d,q models. This paper presents these models with typical results and provides guidelines for their use The dynamic simulation of small power induction motor based on mathematical modelling is proposed in this paper. The dynamic simulation is one of the key steps in the validation of the design process of the motor drive systems and it is needed for eliminating inadvertent design mistakes and the resulting error in the prototype construction and testing. This paper demonstrates the simulation of steady-state performance of induction motor by MATLAB Program Threephase induction motor is modeled and simulated with SIMULINK model.
Mathematical analysis of epidemiological models with heterogeneity
Energy Technology Data Exchange (ETDEWEB)
Van Ark, J.W.
1992-01-01
For many diseases in human populations the disease shows dissimilar characteristics in separate subgroups of the population; for example, the probability of disease transmission for gonorrhea or AIDS is much higher from male to female than from female to male. There is reason to construct and analyze epidemiological models which allow this heterogeneity of population, and to use these models to run computer simulations of the disease to predict the incidence and prevalence of the disease. In the models considered here the heterogeneous population is separated into subpopulations whose internal and external interactions are homogeneous in the sense that each person in the population can be assumed to have all average actions for the people of that subpopulation. The first model considered is an SIRS models; i.e., the Susceptible can become Infected, and if so he eventually Recovers with temporary immunity, and after a period of time becomes Susceptible again. Special cases allow for permanent immunity or other variations. This model is analyzed and threshold conditions are given which determine whether the disease dies out or persists. A deterministic model is presented; this model is constructed using difference equations, and it has been used in computer simulations for the AIDS epidemic in the homosexual population in San Francisco. The homogeneous version and the heterogeneous version of the differential-equations and difference-equations versions of the deterministic model are analyzed mathematically. In the analysis, equilibria are identified and threshold conditions are set forth for the disease to die out if the disease is below the threshold so that the disease-free equilibrium is globally asymptotically stable. Above the threshold the disease persists so that the disease-free equilibrium is unstable and there is a unique endemic equilibrium.
Mathematical and computer modeling of component surface shaping
Lyashkov, A.
2016-04-01
The process of shaping technical surfaces is an interaction of a tool (a shape element) and a component (a formable element or a workpiece) in their relative movements. It was established that the main objects of formation are: 1) a discriminant of a surfaces family, formed by the movement of the shape element relatively the workpiece; 2) an enveloping model of the real component surface obtained after machining, including transition curves and undercut lines; 3) The model of cut-off layers obtained in the process of shaping. When modeling shaping objects there are a lot of insufficiently solved or unsolved issues that make up a single scientific problem - a problem of qualitative shaping of the surface of the tool and then the component surface produced by this tool. The improvement of known metal-cutting tools, intensive development of systems of their computer-aided design requires further improvement of the methods of shaping the mating surfaces. In this regard, an important role is played by the study of the processes of shaping of technical surfaces with the use of the positive aspects of analytical and numerical mathematical methods and techniques associated with the use of mathematical and computer modeling. The author of the paper has posed and has solved the problem of development of mathematical, geometric and algorithmic support of computer-aided design of cutting tools based on computer simulation of the shaping process of surfaces.
Mathematical Modeling of the Origins of Life
Pohorille, Andrew
2006-01-01
The emergence of early metabolism - a network of catalyzed chemical reactions that supported self-maintenance, growth, reproduction and evolution of the ancestors of contemporary cells (protocells) was a critical, but still very poorly understood step on the path from inanimate to animate matter. Here, it is proposed and tested through mathematical modeling of biochemically plausible systems that the emergence of metabolism and its initial evolution towards higher complexity preceded the emergence of a genome. Even though the formation of protocellular metabolism was driven by non-genomic, highly stochastic processes the outcome was largely deterministic, strongly constrained by laws of chemistry. It is shown that such concepts as speciation and fitness to the environment, developed in the context of genomic evolution, also held in the absence of a genome.
Mathematical Model for the Continuous Vacuum Drying
Institute of Scientific and Technical Information of China (English)
DAI Hui-liang
2002-01-01
An improved mathematical model for the continuous vacuum drying of highly viscous and heatsensitive foodstuffs was proposed, The process of continuous vacuum drying was presented as a moving boundary problem of moisture evaporation in cylindrical coordinates. Boundary condition of the first kind for the known functional dependence of the drying body surface temperature on time was considered. Finally, the appropriate system of differential equations was solved numerically and the values of drying rate, integral moisture content of the material, moving boundary position as well as temperature in any point of the material and at any moment time were obtained. This procedure was applied to continuous vacuum drying of foods such as natural cheese and fresh meat paste.
Mathematical modelling on instability of shear fault
Institute of Scientific and Technical Information of China (English)
范天佑
1996-01-01
A study on mathematical modelling on instability of fault is reported.The fracture mechanics and fracture dynamics as a basis of the discussion,and the method of complex variable function (including the conformal mapping and approximate conformal mapping) are employed,and some analytic solutions of the problem in closed form are found.The fault body concept is emphasized and the characteristic size of fault body is introduced.The effect of finite size of the fault body and the effect of the fault propagating speed (especially the effect of the high speed) and their influence on the fault instability are discussed.These results further explain the low-stress drop phenomena observed in earthquake source.
Mathematical Modelling of the Heald Shaft
Directory of Open Access Journals (Sweden)
Bílek Martin
2016-12-01
Full Text Available The manufacturers of weaving equipment recently endeavour to minimise the necessary designing plays in the weaving loom mechanisms. One of the mechanisms most exposed to stress is the shedding motion that defines the held-shaft stroke. Its end part is the heald shaft. The heald shaft constitutes a problematic assembly of the shedding motion. The design employed presently is characterised by dynamic impact loading caused by designing play in the suspension of healds into the heald shaft. During weaving cycle, the healds fly between the main beams of the heald shaft, producing a considerable force pulse. This paper is concerned with the description of dynamic behaviour of the existing design on the basis of mathematical modelling and verification of obtained results by means of experimental analysis.
Some Mathematical Models for ELM Signal
XIE, Hua-sheng
2012-01-01
There is no wide accepted theory for ELM (Edge Localized Mode) yet. Some fusion people feel that we may never get a final theory for ELM and H-mode, since which are too complicated (also related to the unsolved turbulence problem) and with at least three time scales. The only way out is using models. (This is analogous to that we believe quantum mechanics can explain chemistry and biology, but no one can calculate DNA structure from Schrodinger equation directly.) This manuscript gives some possible mathematical approaches to it. I should declare that these are just math toys for me yet. They may inspire to good understandings of ELM and H-mode, may not. Useful or useless, I don't know. One need not take too much care of it. Just for fun and enjoying different interesting ideas.
Mathematical Modeling of Spiral Heat Exchanger
Directory of Open Access Journals (Sweden)
Probal Guha , Vaishnavi Unde
2014-04-01
Full Text Available Compact Heat Exchangers (CHEs are increasingly being used on small and medium scale industries. Due to their compact size and efficient design, they facilitate more efficient heat transfer. Better heat transfer would imply lesser fuel consumption for the operations of the plant, giving improvement to overall efficiency. This reduction in consumption of fuel is a step towards sustainable development. This report exclusively deals with the study the spiral heat exchanger.The design considerations for spiral heat exchanger is that the flow within the spiral has been assumed as flow through a duct and by using Shah London empirical equation for Nusselt number design parameters are further optimized.This is accompanied by a detailed energy balance to generate a concise mathematical model
Biza, Irene; Nardi, Elena; Joel, Gareth
2015-01-01
In this paper we present the results from a study in which 21 mathematics trainee teachers engage with two practice-based tasks in which classroom management interferes with mathematical learning. We investigate the trainees' considerations when they make decisions in classroom situations and how these tasks can trigger their reflections on the…
Jitendra, Asha K.; Nelson, Gena; Pulles, Sandra M.; Kiss, Allyson J.; Houseworth, James
2016-01-01
The purpose of the present review was to evaluate the quality of the research and evidence base for representation of problems as a strategy to enhance the mathematical performance of students with learning disabilities and those at risk for mathematics difficulties. The authors evaluated 25 experimental and quasiexperimental studies according to…
The Use of Models in Teaching Proof by Mathematical Induction
Ron, Gila; Dreyfus, Tommy
2004-01-01
Proof by mathematical induction is known to be conceptually difficult for high school students. This paper presents results from interviews with six experienced high school teachers, concerning the use of models in teaching mathematical induction. Along with creative and adequate use of models, we found explanations, models and examples that…
Mathematics in Nature Modeling Patterns in the Natural World
Adam, John A
2011-01-01
From rainbows, river meanders, and shadows to spider webs, honeycombs, and the markings on animal coats, the visible world is full of patterns that can be described mathematically. Examining such readily observable phenomena, this book introduces readers to the beauty of nature as revealed by mathematics and the beauty of mathematics as revealed in nature.Generously illustrated, written in an informal style, and replete with examples from everyday life, Mathematics in Nature is an excellent and undaunting introduction to the ideas and methods of mathematical modeling. It illustrates how mathem
Mathematical Model for the Mineralization of Bone
Martin, Bruce
1994-01-01
A mathematical model is presented for the transport and precipitation of mineral in refilling osteons. One goal of this model was to explain calcification 'halos,' in which the bone near the haversian canal is more highly mineralized than the more peripheral lamellae, which have been mineralizing longer. It was assumed that the precipitation rate of mineral is proportional to the difference between the local concentration of calcium ions and an equilibrium concentration and that the transport of ions is by either diffusion or some other concentration gradient-dependent process. Transport of ions was assumed to be slowed by the accumulation of mineral in the matrix along the transport path. ne model also mimics bone apposition, slowing of apposition during refilling, and mineralization lag time. It was found that simple diffusion cannot account for the transport of calcium ions into mineralizing bone, because the diffusion coefficient is two orders of magnitude too low. If a more rapid concentration gradient-driven means of transport exists, the model demonstrates that osteonal geometry and variable rate of refilling work together to produce calcification halos, as well as the primary and secondary calcification effect reported in the literature.
An introduction to mathematical modeling a course in mechanics
Oden, Tinsley J
2011-01-01
A modern approach to mathematical modeling, featuring unique applications from the field of mechanics An Introduction to Mathematical Modeling: A Course in Mechanics is designed to survey the mathematical models that form the foundations of modern science and incorporates examples that illustrate how the most successful models arise from basic principles in modern and classical mathematical physics. Written by a world authority on mathematical theory and computational mechanics, the book presents an account of continuum mechanics, electromagnetic field theory, quantum mechanics, and statistical mechanics for readers with varied backgrounds in engineering, computer science, mathematics, and physics. The author streamlines a comprehensive understanding of the topic in three clearly organized sections: Nonlinear Continuum Mechanics introduces kinematics as well as force and stress in deformable bodies; mass and momentum; balance of linear and angular momentum; conservation of energy; and constitutive equation...
Analyzing electrical activities of pancreatic β cells using mathematical models.
Cha, Chae Young; Powell, Trevor; Noma, Akinori
2011-11-01
Bursts of repetitive action potentials are closely related to the regulation of glucose-induced insulin secretion in pancreatic β cells. Mathematical studies with simple β-cell models have established the central principle that the burst-interburst events are generated by the interaction between fast membrane excitation and slow cytosolic components. Recently, a number of detailed models have been developed to simulate more realistic β cell activity based on expanded findings on biophysical characteristics of cellular components. However, their complex structures hinder our intuitive understanding of the underlying mechanisms, and it is becoming more difficult to dissect the role of a specific component out of the complex network. We have recently developed a new detailed model by incorporating most of ion channels and transporters recorded experimentally (the Cha-Noma model), yet the model satisfies the charge conservation law and reversible responses to physiological stimuli. Here, we review the mechanisms underlying bursting activity by applying mathematical analysis tools to representative simple and detailed models. These analyses include time-based simulation, bifurcation analysis and lead potential analysis. In addition, we introduce a new steady-state I-V (ssI-V) curve analysis. We also discuss differences in electrical signals recorded from isolated single cells or from cells maintaining electrical connections within multi-cell preparations. Towards this end, we perform simulations with our detailed pancreatic β-cell model.
Mathematical model insights into arsenic detoxification
Directory of Open Access Journals (Sweden)
Nijhout H Frederik
2011-08-01
Full Text Available Abstract Background Arsenic in drinking water, a major health hazard to millions of people in South and East Asia and in other parts of the world, is ingested primarily as trivalent inorganic arsenic (iAs, which then undergoes hepatic methylation to methylarsonic acid (MMAs and a second methylation to dimethylarsinic acid (DMAs. Although MMAs and DMAs are also known to be toxic, DMAs is more easily excreted in the urine and therefore methylation has generally been considered a detoxification pathway. A collaborative modeling project between epidemiologists, biologists, and mathematicians has the purpose of explaining existing data on methylation in human studies in Bangladesh and also testing, by mathematical modeling, effects of nutritional supplements that could increase As methylation. Methods We develop a whole body mathematical model of arsenic metabolism including arsenic absorption, storage, methylation, and excretion. The parameters for arsenic methylation in the liver were taken from the biochemical literature. The transport parameters between compartments are largely unknown, so we adjust them so that the model accurately predicts the urine excretion rates of time for the iAs, MMAs, and DMAs in single dose experiments on human subjects. Results We test the model by showing that, with no changes in parameters, it predicts accurately the time courses of urinary excretion in mutiple dose experiments conducted on human subjects. Our main purpose is to use the model to study and interpret the data on the effects of folate supplementation on arsenic methylation and excretion in clinical trials in Bangladesh. Folate supplementation of folate-deficient individuals resulted in a 14% decrease in arsenicals in the blood. This is confirmed by the model and the model predicts that arsenicals in the liver will decrease by 19% and arsenicals in other body stores by 26% in these same individuals. In addition, the model predicts that arsenic
Mathematical model and simulation of partial penetrated weld pool
Institute of Scientific and Technical Information of China (English)
无
2001-01-01
The qualitative analysis on the behavior of partial penetrated weld pool transferring from pulsed peak current to base current in pulsed TIG welding is carried out in this paper. Based on the analysis results, the mathematical models for 3D liquid surface shape of partial penetrated weld pool in pulsed TIG welding are created including surface potential energy model, gravitational energy model and volumetric potential energy. The numerical simulation with these models and the experiments on low carbon steel are carried out using the software Surface Evolver. The simulation results and model are then amended with experimental results. Two important characteristic quantities, the liquid metal coverage ratio and the stripping width of liquid metal, are put forward in this paper, which paves a way for further weld pool full penetration control.
A Mathematical Model of a Simple Amplifier Using a Ferroelectric Transistor
Sayyah, Rana; Hunt, Mitchell; MacLeod, Todd C.; Ho, Fat D.
2009-01-01
This paper presents a mathematical model characterizing the behavior of a simple amplifier using a FeFET. The model is based on empirical data and incorporates several variables that affect the output, including frequency, load resistance, and gate-to-source voltage. Since the amplifier is the basis of many circuit configurations, a mathematical model that describes the behavior of a FeFET-based amplifier will help in the integration of FeFETs into many other circuits.
Impulsive mathematical modeling of ascorbic acid metabolism in healthy subjects.
Bachar, Mostafa; Raimann, Jochen G; Kotanko, Peter
2016-03-07
In this work, we develop an impulsive mathematical model of Vitamin C (ascorbic acid) metabolism in healthy subjects for daily intake over a long period of time. The model includes the dynamics of ascorbic acid plasma concentration, the ascorbic acid absorption in the intestines and a novel approach to quantify the glomerular excretion of ascorbic acid. We investigate qualitative and quantitative dynamics. We show the existence and uniqueness of the global asymptotic stability of the periodic solution. We also perform a numerical simulation for the entire time period based on published data reporting parameters reflecting ascorbic acid metabolism at different oral doses of ascorbic acid.
Image Filtering Based on Mathematical Morphology and Visual Perception Principle
Institute of Scientific and Technical Information of China (English)
JINGXiaojun; YUNong; SHANGYong
2004-01-01
The operation of a morphological filter can be divided into two basic problems that include morphological operation and Structuring element (SE) selection. The rules for morphological operations are predefined, so the filter's properties depend merely on the selection of SE. How to design adaptively the optimal morphological filter so as to automatically and delicately complete the tasks of target detection and recognition, becomes one of the current research hotspots and subtle technical problems. Based on the filtering theory of the mathematical morphology, by introducing appropriate visual perception principle, this paper presents how to design the filtering architecture and its target detection model through the optimal parameter training. By this way it can provide good detection results and robust adaptability to image targets with clutter background. It is sure to provide a new approach to automatic target recognition with mathematical morphology theory.
Filler segmentation of SEM paper images based on mathematical morphology.
Ait Kbir, M; Benslimane, Rachid; Princi, Elisabetta; Vicini, Silvia; Pedemonte, Enrico
2007-07-01
Recent developments in microscopy and image processing have made digital measurements on high-resolution images of fibrous materials possible. This helps to gain a better understanding of the structure and other properties of the material at micro level. In this paper SEM image segmentation based on mathematical morphology is proposed. In fact, paper models images (Whatman, Murillo, Watercolor, Newsprint paper) selected in the context of the Euro Mediterranean PaperTech Project have different distributions of fibers and fillers, caused by the presence of SiAl and CaCO3 particles. It is a microscopy challenge to make filler particles in the sheet distinguishable from the other components of the paper surface. This objectif is reached here by using switable strutural elements and mathematical morphology operators.
Application of Mathematical Modeling Activities in Costarican High School Education
Directory of Open Access Journals (Sweden)
Karen Porras-Lizano
2015-01-01
Full Text Available This paper describes the experience gained in implementing mathematical modeling activities as a methodological strategy in teaching issues such as proportions, with a group of eighth year of an academic-day-school, located in the province of San Jose, Costa Rica in 2012. Different techniques for gathering information were applied, such as participant observation and questionnaires. Among the relevant results are the cyclical development of mathematical thinking of students in the stages of mathematical modeling (description, manipulation, prediction and validation for solving the problem; developing of teamwork skills; and appreciation of mathematics as a useful and effective discipline. To resolve the activities proposed in this study, social interactions such as sharing information, thoughts and ideas, were generated, stimulating the zone of proximal development of the participating students. Likewise, the mathematical modeling activities allowed students to have a positive role in mathematics classes, stimulating, in turn, a different attitude compared to regular classes.
Web-Based Implementation of Discrete Mathematics
Love, Tanzy; Keinert, Fritz; Shelley, Mack
2006-01-01
The Department of Mathematics at Iowa State University teaches a freshman-level Discrete Mathematics course with total enrollment of about 1,800 students per year. The traditional format includes large lectures, with about 150 students each, taught by faculty and temporary instructors in two class sessions per week and recitation sections, with…
一种基于VB的实用轴对中数学模型研究%Study on a Practical Shaft Alignment Mathematical Model Based on VB
Institute of Scientific and Technical Information of China (English)
慕丽; 王欣威
2011-01-01
A shaft alignment measuring principle which was different from the traditional measuring principle was proposed based on the existing theroy. The mathematic model was established and the shaft alignment principle was analyzed. The relative position of two axes could be obtained by calculating the spot's coordinate on the photosensitive surface which was irradiated by LD. The adjust ment formula of slave axis' forefoot and rear foot could be derived. The alignment purpose could be accomplished by adjusting the axis' position. Interface and data processing were designed with VB. It is verified that the measurement method is simple, accurate and ef fective by detecting the real engineering quantity.%在参考现有激光对中仪原理的基础上,提出一种不同于传统对中测量的测量原理.建立激光对中仪的数学模型并分析其对中原理.通过计算LD所发射的光信号落在PSD光敏面上的光斑坐标,求得两轴的相对位置,从而推导出从动轴的前脚和后脚的调整公式,调整轴的位置达到对中目的.利用VB进行界面设计和数据处理.同时进行了实际工程量检测,验证了该测量方法的简便性、准确性和有效性.
Assessment of mathematical models for the flow in directional solidification
Lu, Jay W.; Chen, Falin
1997-02-01
In a binary solution unidirectionally solidified from below, the bulk melt and the eutectic solid is separated by a dendritic mushy zone. The mathematical formulation governing the fluid motion shall thus consist of the equations in the bulk melt and the mushy zone and the associated boundary conditions. In the bulk melt, assuming that the melt is a Newtonian fluid, the governing equations are the continuity equation, the Navier-Stokes equations, the heat conservation equation, and the solute conservation equation. In the mushy layer, however, the formulation of the momentum equation and the associated boundary conditions are diversified in previous investigations. In this paper, we discuss three mathematical models, which had been previously applied to study the flow induced by the solidification of binary solutions cooling from below. The assessment is given on the bases of the stability characteristics of the convective flow and the comparison between the numerical and experimental results.
Mathematical modeling and signal processing in speech and hearing sciences
Xin, Jack
2014-01-01
The aim of the book is to give an accessible introduction of mathematical models and signal processing methods in speech and hearing sciences for senior undergraduate and beginning graduate students with basic knowledge of linear algebra, differential equations, numerical analysis, and probability. Speech and hearing sciences are fundamental to numerous technological advances of the digital world in the past decade, from music compression in MP3 to digital hearing aids, from network based voice enabled services to speech interaction with mobile phones. Mathematics and computation are intimately related to these leaps and bounds. On the other hand, speech and hearing are strongly interdisciplinary areas where dissimilar scientific and engineering publications and approaches often coexist and make it difficult for newcomers to enter.
Marshall, Neil; Buteau, Chantal
2014-01-01
As part of their undergraduate mathematics curriculum, students at Brock University learn to create and use computer-based tools with dynamic, visual interfaces, called Exploratory Objects, developed for the purpose of conducting pure or applied mathematical investigations. A student's Development Process Model of creating and using an Exploratory…
Huang, Tzu-Hua; Liu, Yuan-Chen; Chang, Hsiu-Chen
2012-01-01
This study developed a computer-assisted mathematical problem-solving system in the form of a network instruction website to help low-achieving second- and third-graders in mathematics with word-based addition and subtraction questions in Taiwan. According to Polya's problem-solving model, the system is designed to guide these low-achievers…
Managing mathematical modelling by guiding and monitoring
Scholten, H.; Beulens, A.J.M.
2006-01-01
This case study discusses how a knowledge base can be used to solve complex multi-disciplinary problems through a model based approach in the water management sector. We learn how successful execution and completion of multi-disciplinary complex projects can be supported through a knowledge-based sy
Developing Student-Centered Learning Model to Improve High Order Mathematical Thinking Ability
Saragih, Sahat; Napitupulu, Elvis
2015-01-01
The purpose of this research was to develop student-centered learning model aiming to improve high order mathematical thinking ability of junior high school students of based on curriculum 2013 in North Sumatera, Indonesia. The special purpose of this research was to analyze and to formulate the purpose of mathematics lesson in high order…
Holahan, Patricia J.; Jurkat, M. Peter; Friedman, Edward A.
2000-01-01
Describes the development of the Mentor Teacher Model that trained middle school and high school mathematics teachers in New Jersey as mentor teachers in the effective use of computer-based technologies for teaching mathematics. Highlights include student-centered teaching methods; cooperative learning; problem-solving activities; and technology…
Mathematics Teacher TPACK Standards and Development Model
Niess, Margaret L.; Ronau, Robert N.; Shafer, Kathryn G.; Driskell, Shannon O.; Harper, Suzanne R.; Johnston, Christopher; Browning, Christine; Ozgun-Koca, S. Asli; Kersaint, Gladis
2009-01-01
What knowledge is needed to teach mathematics with digital technologies? The overarching construct, called technology, pedagogy, and content knowledge (TPACK), has been proposed as the interconnection and intersection of technology, pedagogy, and content knowledge. Mathematics Teacher TPACK Standards offer guidelines for thinking about this…
Modelling Mathematical Reasoning in Physics Education
Uhden, Olaf; Karam, Ricardo; Pietrocola, Mauricio; Pospiech, Gesche
2012-01-01
Many findings from research as well as reports from teachers describe students' problem solving strategies as manipulation of formulas by rote. The resulting dissatisfaction with quantitative physical textbook problems seems to influence the attitude towards the role of mathematics in physics education in general. Mathematics is often seen as a…
The limitations of mathematical modeling in high school physics education
Forjan, Matej
The theme of the doctoral dissertation falls within the scope of didactics of physics. Theoretical analysis of the key constraints that occur in the transmission of mathematical modeling of dynamical systems into field of physics education in secondary schools is presented. In an effort to explore the extent to which current physics education promotes understanding of models and modeling, we analyze the curriculum and the three most commonly used textbooks for high school physics. We focus primarily on the representation of the various stages of modeling in the solved tasks in textbooks and on the presentation of certain simplifications and idealizations, which are in high school physics frequently used. We show that one of the textbooks in most cases fairly and reasonably presents the simplifications, while the other two half of the analyzed simplifications do not explain. It also turns out that the vast majority of solved tasks in all the textbooks do not explicitly represent model assumptions based on what we can conclude that in high school physics the students do not develop sufficiently a sense of simplification and idealizations, which is a key part of the conceptual phase of modeling. For the introduction of modeling of dynamical systems the knowledge of students is also important, therefore we performed an empirical study on the extent to which high school students are able to understand the time evolution of some dynamical systems in the field of physics. The research results show the students have a very weak understanding of the dynamics of systems in which the feedbacks are present. This is independent of the year or final grade in physics and mathematics. When modeling dynamical systems in high school physics we also encounter the limitations which result from the lack of mathematical knowledge of students, because they don't know how analytically solve the differential equations. We show that when dealing with one-dimensional dynamical systems
Mathematical modeling of Chikungunya fever control
Hincapié-Palacio, Doracelly; Ospina, Juan
2015-05-01
Chikungunya fever is a global concern due to the occurrence of large outbreaks, the presence of persistent arthropathy and its rapid expansion throughout various continents. Globalization and climate change have contributed to the expansion of the geographical areas where mosquitoes Aedes aegypti and Aedes albopictus (Stegomyia) remain. It is necessary to improve the techniques of vector control in the presence of large outbreaks in The American Region. We derive measures of disease control, using a mathematical model of mosquito-human interaction, by means of three scenarios: a) a single vector b) two vectors, c) two vectors and human and non-human reservoirs. The basic reproductive number and critical control measures were deduced by using computer algebra with Maple (Maplesoft Inc, Ontario Canada). Control measures were simulated with parameter values obtained from published data. According to the number of households in high risk areas, the goals of effective vector control to reduce the likelihood of mosquito-human transmission would be established. Besides the two vectors, if presence of other non-human reservoirs were reported, the monthly target of effective elimination of the vector would be approximately double compared to the presence of a single vector. The model shows the need to periodically evaluate the effectiveness of vector control measures.
Simple mathematical models of gene regulatory dynamics
Mackey, Michael C; Tyran-Kamińska, Marta; Zeron, Eduardo S
2016-01-01
This is a short and self-contained introduction to the field of mathematical modeling of gene-networks in bacteria. As an entry point to the field, we focus on the analysis of simple gene-network dynamics. The notes commence with an introduction to the deterministic modeling of gene-networks, with extensive reference to applicable results coming from dynamical systems theory. The second part of the notes treats extensively several approaches to the study of gene-network dynamics in the presence of noise—either arising from low numbers of molecules involved, or due to noise external to the regulatory process. The third and final part of the notes gives a detailed treatment of three well studied and concrete examples of gene-network dynamics by considering the lactose operon, the tryptophan operon, and the lysis-lysogeny switch. The notes contain an index for easy location of particular topics as well as an extensive bibliography of the current literature. The target audience of these notes are mainly graduat...
Mathematical model I. Electron and quantum mechanics
Gadre, Nitin Ramchandra
2011-03-01
The basic particle electron obeys various theories like electrodynamics, quantum mechanics and special relativity. Particle under different experimental conditions behaves differently, allowing us to observe different characteristics which become basis for these theories. In this paper, we have made an attempt to suggest a classical picture by studying the requirements of these three modern theories. The basic presumption is: There must be certain structural characteristics in a particle like electron which make it obey postulates of modern theories. As it is `difficult' to find structure of electron experimentally, we make a mathematical attempt. For a classical approach, we require well defined systems and we have studied a system with two charged particles, proton and electron in a hydrogen atom. An attempt has been made to give a model to describe electron as seen by the proton. We then discuss how the model can satisfy the requirements of the three modern theories in a classical manner. The paper discusses basic aspects of relativity and electrodynamics. However the focus of the paper is on quantum mechanics.
Mathematical model I. Electron and quantum mechanics
Directory of Open Access Journals (Sweden)
Nitin Ramchandra Gadre
2011-03-01
Full Text Available The basic particle electron obeys various theories like electrodynamics, quantum mechanics and special relativity. Particle under different experimental conditions behaves differently, allowing us to observe different characteristics which become basis for these theories. In this paper, we have made an attempt to suggest a classical picture by studying the requirements of these three modern theories. The basic presumption is: There must be certain structural characteristics in a particle like electron which make it obey postulates of modern theories. As it is ‘difficult’ to find structure of electron experimentally, we make a mathematical attempt. For a classical approach, we require well defined systems and we have studied a system with two charged particles, proton and electron in a hydrogen atom. An attempt has been made to give a model to describe electron as seen by the proton. We then discuss how the model can satisfy the requirements of the three modern theories in a classical manner. The paper discusses basic aspects of relativity and electrodynamics. However the focus of the paper is on quantum mechanics.
Mathematical modeling of the neuron morphology using two dimensional images.
Rajković, Katarina; Marić, Dušica L; Milošević, Nebojša T; Jeremic, Sanja; Arsenijević, Valentina Arsić; Rajković, Nemanja
2016-02-01
In this study mathematical analyses such as the analysis of area and length, fractal analysis and modified Sholl analysis were applied on two dimensional (2D) images of neurons from adult human dentate nucleus (DN). Using mathematical analyses main morphological properties were obtained including the size of neuron and soma, the length of all dendrites, the density of dendritic arborization, the position of the maximum density and the irregularity of dendrites. Response surface methodology (RSM) was used for modeling the size of neurons and the length of all dendrites. However, the RSM model based on the second-order polynomial equation was only possible to apply to correlate changes in the size of the neuron with other properties of its morphology. Modeling data provided evidence that the size of DN neurons statistically depended on the size of the soma, the density of dendritic arborization and the irregularity of dendrites. The low value of mean relative percent deviation (MRPD) between the experimental data and the predicted neuron size obtained by RSM model showed that model was suitable for modeling the size of DN neurons. Therefore, RSM can be generally used for modeling neuron size from 2D images.
Energy Technology Data Exchange (ETDEWEB)
Willenbring, James M.; Bartlett, Roscoe Ainsworth (Oak Ridge National Laboratory, Oak Ridge, TN); Heroux, Michael Allen
2012-01-01
Software lifecycles are becoming an increasingly important issue for computational science and engineering (CSE) software. The process by which a piece of CSE software begins life as a set of research requirements and then matures into a trusted high-quality capability is both commonplace and extremely challenging. Although an implicit lifecycle is obviously being used in any effort, the challenges of this process - respecting the competing needs of research vs. production - cannot be overstated. Here we describe a proposal for a well-defined software lifecycle process based on modern Lean/Agile software engineering principles. What we propose is appropriate for many CSE software projects that are initially heavily focused on research but also are expected to eventually produce usable high-quality capabilities. The model is related to TriBITS, a build, integration and testing system, which serves as a strong foundation for this lifecycle model, and aspects of this lifecycle model are ingrained in the TriBITS system. Here, we advocate three to four phases or maturity levels that address the appropriate handling of many issues associated with the transition from research to production software. The goals of this lifecycle model are to better communicate maturity levels with customers and to help to identify and promote Software Engineering (SE) practices that will help to improve productivity and produce better software. An important collection of software in this domain is Trilinos, which is used as the motivation and the initial target for this lifecycle model. However, many other related and similar CSE (and non-CSE) software projects can also make good use of this lifecycle model, especially those that use the TriBITS system. Indeed this lifecycle process, if followed, will enable large-scale sustainable integration of many complex CSE software efforts across several institutions.
MATHEMATICAL MODELING OF AC ELECTRIC POINT MOTOR
Directory of Open Access Journals (Sweden)
S. YU. Buryak
2014-03-01
Full Text Available Purpose. In order to ensure reliability, security, and the most important the continuity of the transportation process, it is necessary to develop, implement, and then improve the automated methods of diagnostic mechanisms, devices and rail transport systems. Only systems that operate in real time mode and transmit data on the instantaneous state of the control objects can timely detect any faults and thus provide additional time for their correction by railway employees. Turnouts are one of the most important and responsible components, and therefore require the development and implementation of such diagnostics system.Methodology. Achieving the goal of monitoring and control of railway automation objects in real time is possible only with the use of an automated process of the objects state diagnosing. For this we need to know the diagnostic features of a control object, which determine its state at any given time. The most rational way of remote diagnostics is the shape and current spectrum analysis that flows in the power circuits of railway automatics. Turnouts include electric motors, which are powered by electric circuits, and the shape of the current curve depends on both the condition of the electric motor, and the conditions of the turnout maintenance. Findings. For the research and analysis of AC electric point motor it was developed its mathematical model. The calculation of parameters and interdependencies between the main factors affecting the operation of the asynchronous machine was conducted. The results of the model operation in the form of time dependences of the waveform curves of current on the load on engine shaft were obtained. Originality. During simulation the model of AC electric point motor, which satisfies the conditions of adequacy was built. Practical value. On the basis of the constructed model we can study the AC motor in various mode of operation, record and analyze current curve, as a response to various changes
Mathematical models in marketing a collection of abstracts
Funke, Ursula H
1976-01-01
Mathematical models can be classified in a number of ways, e.g., static and dynamic; deterministic and stochastic; linear and nonlinear; individual and aggregate; descriptive, predictive, and normative; according to the mathematical technique applied or according to the problem area in which they are used. In marketing, the level of sophistication of the mathe matical models varies considerably, so that a nurnber of models will be meaningful to a marketing specialist without an extensive mathematical background. To make it easier for the nontechnical user we have chosen to classify the models included in this collection according to the major marketing problem areas in which they are applied. Since the emphasis lies on mathematical models, we shall not as a rule present statistical models, flow chart models, computer models, or the empirical testing aspects of these theories. We have also excluded competitive bidding, inventory and transportation models since these areas do not form the core of ·the market...
Garcia-Santillan, Arturo; Moreno-Garcia, Elena; Escalera-Chávez, Milka E.; Rojas-Kramer, Carlos A.; Pozos-Texon, Felipe
2016-01-01
Most mathematics students show a definite tendency toward an attitudinal deficiency, which can be primarily understood as intolerance to the matter, affecting their scholar performance adversely. In addition, information and communication technologies have been gradually included within the process of teaching mathematics. Such adoption of technology modified the educational process, thus generating a meaningful impact as presented by studies carried out by Galbraith and Haines (2000). They d...
Variational Data Assimilation Technique in Mathematical Modeling of Ocean Dynamics
Agoshkov, V. I.; Zalesny, V. B.
2012-03-01
Problems of the variational data assimilation for the primitive equation ocean model constructed at the Institute of Numerical Mathematics, Russian Academy of Sciences are considered. The model has a flexible computational structure and consists of two parts: a forward prognostic model, and its adjoint analog. The numerical algorithm for the forward and adjoint models is constructed based on the method of multicomponent splitting. The method includes splitting with respect to physical processes and space coordinates. Numerical experiments are performed with the use of the Indian Ocean and the World Ocean as examples. These numerical examples support the theoretical conclusions and demonstrate the rationality of the approach using an ocean dynamics model with an observed data assimilation procedure.
Mathematical model of radon activity measurements
Energy Technology Data Exchange (ETDEWEB)
Paschuk, Sergei A.; Correa, Janine N.; Kappke, Jaqueline; Zambianchi, Pedro, E-mail: sergei@utfpr.edu.br, E-mail: janine_nicolosi@hotmail.com [Universidade Tecnologica Federal do Parana (UTFPR), Curitiba, PR (Brazil); Denyak, Valeriy, E-mail: denyak@gmail.com [Instituto de Pesquisa Pele Pequeno Principe, Curitiba, PR (Brazil)
2015-07-01
Present work describes a mathematical model that quantifies the time dependent amount of {sup 222}Rn and {sup 220}Rn altogether and their activities within an ionization chamber as, for example, AlphaGUARD, which is used to measure activity concentration of Rn in soil gas. The differential equations take into account tree main processes, namely: the injection of Rn into the cavity of detector by the air pump including the effect of the traveling time Rn takes to reach the chamber; Rn release by the air exiting the chamber; and radioactive decay of Rn within the chamber. Developed code quantifies the activity of {sup 222}Rn and {sup 220}Rn isotopes separately. Following the standard methodology to measure Rn activity in soil gas, the air pump usually is turned off over a period of time in order to avoid the influx of Rn into the chamber. Since {sup 220}Rn has a short half-life time, approximately 56s, the model shows that after 7 minutes the activity concentration of this isotope is null. Consequently, the measured activity refers to {sup 222}Rn, only. Furthermore, the model also addresses the activity of {sup 220}Rn and {sup 222}Rn progeny, which being metals represent potential risk of ionization chamber contamination that could increase the background of further measurements. Some preliminary comparison of experimental data and theoretical calculations is presented. Obtained transient and steady-state solutions could be used for planning of Rn in soil gas measurements as well as for accuracy assessment of obtained results together with efficiency evaluation of chosen measurements procedure. (author)
A Mathematical Model for Freeze-Drying
Institute of Scientific and Technical Information of China (English)
无
2000-01-01
Based on the experiments on freeze-drying carrot and potato slabs, the effects of some parameters, such as heating temperature and pressure on the freeze-drying process are examined. A simple model of freeze-drying is established to predict drying time and the mass variations of materials during the drying. The experimental results agree well with those calculated by the model.
A mathematical model of the Mafia game
Migdal, Piotr
2010-01-01
Mafia (also called Werewolf) is a party game. The participants are divided into two competing groups: citizens and a mafia. The objective is to eliminate the opponent group. The game consists of two consecutive phases (day and night) and a certain set of actions (e.g. lynching during day). The mafia members have additional powers (knowing each other, killing during night) whereas the citizens are more numerous. We propose a simple mathematical model of the game, which is essentially a pure death process with discrete time. We find closed-form formulas for mafia winning chances $w(n,m)$ as well as for evolution of the game. Moreover, we investigate discrete properties of results, as well as its continuous-time approximation. I turns out that a relatively small number of the mafia members $m$ (among $n$ players) give $50:50$ winning chances, i.e. $m\\approx\\sqrt{n}$. Furthermore, the game strongly depends on the parity of the total number of players.
Mathematical modelling for nanotube bundle oscillators
Thamwattana, Ngamta; Cox, Barry J.; Hill, James M.
2009-07-01
This paper investigates the mechanics of a gigahertz oscillator comprising a nanotube oscillating within the centre of a uniform concentric ring or bundle of nanotubes. The study is also extended to the oscillation of a fullerene inside a nanotube bundle. In particular, certain fullerene-nanotube bundle oscillators are studied, namely C60-carbon nanotube bundle, C60-boron nitride nanotube bundle, B36N36-carbon nanotube bundle and B36N36-boron nitride nanotube bundle. Using the Lennard-Jones potential and the continuum approach, we obtain a relation between the bundle radius and the radii of the nanotubes forming the bundle, as well as the optimum bundle size which gives rise to the maximum oscillatory frequency for both the fullerene and the nanotube bundle oscillators. While previous studies in this area have been undertaken through molecular dynamics simulations, this paper emphasizes the use of applied mathematical modelling techniques which provides considerable insight into the underlying mechanisms. The paper presents a synopsis of the major results derived in detail by the present authors in [1, 2].
Mathematical modeling of the human knee joint
Energy Technology Data Exchange (ETDEWEB)
Ricafort, Juliet [Univ. of Southern California, Los Angeles, CA (United States). Dept. of Biomedical Engineering
1996-05-01
A model was developed to determine the forces exerted by several flexor and extensor muscles of the human knee under static conditions. The following muscles were studied: the gastrocnemius, biceps femoris, semitendinosus, semimembranosus, and the set of quadricep muscles. The tibia and fibula were each modeled as rigid bodies; muscles were modeled by their functional lines of action in space. Assumptions based on previous data were used to resolve the indeterminacy.
A basic mathematical and numerical model for gas injection
Molenaar, J.
1996-01-01
In this paper we discuss a mathematical model for gas storage processes. In addition we outline an approach for numerical simulations. The focus is on model assumptions and limitations with respect to the software to be developed.
Generalized Mathematical Model for Hot Rolling Process of Plate
Institute of Scientific and Technical Information of China (English)
Zhenshan CUI; Bingye XU
2003-01-01
A generalized mathematical model is developed to predict the changes of temperature, rolling pressure, strain,strain rate, and austenite grain size for plate hot rolling and cooling processes. The model is established mainly by incorporating analytical an
Symmetrization of mathematical model of charge transport in semiconductors
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Alexander M. Blokhin
2002-11-01
Full Text Available A mathematical model of charge transport in semiconductors is considered. The model is a quasilinear system of differential equations. A problem of finding an additional entropy conservation law and system symmetrization are solved.
Directory of Open Access Journals (Sweden)
Universidade Estadual do Oeste do Paraná
2012-12-01
Full Text Available This paper presents an analysis of scientific communications published in the IV Mathematical Modeling National Conference (CNMEM in the Brazilian abbreviation, which took place in 2005. The analysis consists of a meta-analytical and content qualitative approach, aided by the software Atlas T.i. The data collected was originated in the above mentioned conference which is the first of the three which will be analyzed in the study that aims to unveil the research on Mathematical Modeling in Brazil. The categories established in this paper and which will be interpreted are: a Meta-study on Mathematics Modeling; b Modeling application; c Articulation between Modeling and other theories, and d Modeling and teachers education.
Quantum Gravity Mathematical Models and Experimental Bounds
Fauser, Bertfried; Zeidler, Eberhard
2007-01-01
The construction of a quantum theory of gravity is the most fundamental challenge confronting contemporary theoretical physics. The different physical ideas which evolved while developing a theory of quantum gravity require highly advanced mathematical methods. This book presents different mathematical approaches to formulate a theory of quantum gravity. It represents a carefully selected cross-section of lively discussions about the issue of quantum gravity which took place at the second workshop "Mathematical and Physical Aspects of Quantum Gravity" in Blaubeuren, Germany. This collection covers in a unique way aspects of various competing approaches. A unique feature of the book is the presentation of different approaches to quantum gravity making comparison feasible. This feature is supported by an extensive index. The book is mainly addressed to mathematicians and physicists who are interested in questions related to mathematical physics. It allows the reader to obtain a broad and up-to-date overview on ...
Research of inverse mathematical model to high-speed trains
Institute of Scientific and Technical Information of China (English)
朱涛; 肖守讷; 马卫华; 阳光武
2014-01-01
Operation safety and stability of the train mainly depend on the interaction between the wheel and rail. Knowledge of wheel/rail contact force is important for vehicle control systems that aim to enhance vehicle stability and passenger safety. Since wheel/rail contact forces of high-speed train are very difficult to measure directly, a new estimation process for wheel/rail contact forces was introduced in this work. Based on the state space equation, dynamic programming methods and the Bellman principle of optimality, the main theoretical derivation of the inversion mathematical model was given. The new method overcomes the weakness of large fluctuations which exist in current inverse techniques. High-speed vehicle was chosen as the research object, accelerations of axle box as input conditions, 10 degrees of freedom vertical vibration model and 17 degrees of freedom lateral vibration model were established, respectively. Under 250 km/h, the vertical and lateral wheel/rail forces were identified. From the time domain and frequency domain, the comparison of the results between inverse and SIMPACK models were given. The results show that the inverse mathematical model has high precision for inversing the wheel/rail contact forces of an operation high-speed vehicle.
Mathematical modelling in engineering: A proposal to introduce linear algebra concepts
Andrea Dorila Cárcamo; Joan Vicenç Gómez; Josep María Fortuny
2016-01-01
The modern dynamic world requires that basic science courses for engineering, including linear algebra, emphasize the development of mathematical abilities primarily associated with modelling and interpreting, which aren´t limited only to calculus abilities. Considering this, an instructional design was elaborated based on mathematic modelling and emerging heuristic models for the construction of specific linear algebra concepts: span and spanning set. This was applied to first year e...
Mathematical modelling in engineering: a proposal to introduce linear algebra concepts
Cárcamo Bahamonde, Andrea Dorila; Gómez Urgellés, Joan Vicenç; Fortuny Aymeni, José María
2016-01-01
The modern dynamic world requires that basic science courses for engineering, including linear algebra, emphasize the development of mathematical abilities primarily associated with modelling and interpreting, which aren´t limited only to calculus abilities. Considering this, an instructional design was elaborated based on mathematic modelling and emerging heuristic models for the construction of specific linear algebra concepts: span and spanning set. This was applied to first year engineeri...
Mathematical modelling in engineering: a proposal to introduce linear algebra concepts
Cárcamo Bahamonde, Andrea; Gómez Urgellés, Joan Vicenç; Fortuny Aymemi, Josep Maria
2016-01-01
The modern dynamic world requires that basic science courses for engineering, including linear algebra, emphasize the development of mathematical abilities primarily associated with modelling and interpreting, which aren´t limited only to calculus abilities. Considering this, an instructional design was elaborated based on mathematic modelling and emerging heuristic models for the construction of specific linear algebra concepts: span and spanning set. This was applied to first year engineer...
Typhoid transmission: a historical perspective on mathematical model development.
Bakach, Iurii; Just, Matthew R; Gambhir, Manoj; Fung, Isaac Chun-Hai
2015-11-01
Mathematical models of typhoid transmission were first developed nearly half a century ago. To facilitate a better understanding of the historical development of this field, we reviewed mathematical models of typhoid and summarized their structures and limitations. Eleven models, published in 1971 to 2014, were reviewed. While models of typhoid vaccination are well developed, we highlight the need to better incorporate water, sanitation and hygiene interventions into models of typhoid and other foodborne and waterborne diseases. Mathematical modeling is a powerful tool to test and compare different intervention strategies which is important in the world of limited resources. By working collaboratively, epidemiologists and mathematicians should build better mathematical models of typhoid transmission, including pharmaceutical and non-pharmaceutical interventions, which will be useful in epidemiological and public health practice.
Mathematical model of various statements of C-type Language
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Manoj Kumar Srivastav
2013-12-01
Full Text Available Some of the important components of high level languages are statements, keywords, variable declarations, arrays, user defined functions etc. In case of object oriented programming language we use class, object, inheritance, operator overloading, function overloading, polymorphism etc. There are some common category of statements such as control statement, loop statements etc. Pointers are also one important concept in C-language. User defined functions, function subprograms or subroutines are also important concepts in different programming languages. The language like ALGOL was developed using Chomsky context free grammar. The similar concept used in C-type languages. The high level languages are now based on mathematical derivations and logic. Most of the components of any high level language can be obtained from simple mathematical logic and derivations. In the present study the authors have tried to give some unified mathematical model of few statements, arrays, user defined functions of C-language. However, the present method may further be extended to any other high level language.
Anku, Sitsofe E.
1997-09-01
Using the reform documents of the National Council of Teachers of Mathematics (NCTM) (NCTM, 1989, 1991, 1995), a theory-based multi-dimensional assessment framework (the "SEA" framework) which should help expand the scope of assessment in mathematics is proposed. This framework uses a context based on mathematical reasoning and has components that comprise mathematical concepts, mathematical procedures, mathematical communication, mathematical problem solving, and mathematical disposition.
An Assessment Model for Proof Comprehension in Undergraduate Mathematics
Mejia-Ramos, Juan Pablo; Fuller, Evan; Weber, Keith; Rhoads, Kathryn; Samkoff, Aron
2012-01-01
Although proof comprehension is fundamental in advanced undergraduate mathematics courses, there has been limited research on what it means to understand a mathematical proof at this level and how such understanding can be assessed. In this paper, we address these issues by presenting a multidimensional model for assessing proof comprehension in…
Teaching Writing and Communication in a Mathematical Modeling Course
Linhart, Jean Marie
2014-01-01
Writing and communication are essential skills for success in the workplace or in graduate school, yet writing and communication are often the last thing that instructors think about incorporating into a mathematics course. A mathematical modeling course provides a natural environment for writing assignments. This article is an analysis of the…
Mathematical Biology Modules Based on Modern Molecular Biology and Modern Discrete Mathematics
Robeva, Raina; Davies, Robin; Hodge, Terrell; Enyedi, Alexander
2010-01-01
We describe an ongoing collaborative curriculum materials development project between Sweet Briar College and Western Michigan University, with support from the National Science Foundation. We present a collection of modules under development that can be used in existing mathematics and biology courses, and we address a critical national need to introduce students to mathematical methods beyond the interface of biology with calculus. Based on ongoing research, and designed to use the project-...
Mathematical Model of a Lithium/Thionyl Chloride Battery
Energy Technology Data Exchange (ETDEWEB)
Jain, M.; Jungst, R.G.; Nagasubramanian, G.; Weidner, J.W.
1998-11-24
A mathematical model of a spirally wound lithium/thionyl chloride primary battery has been developed ~d used for parameter estimation and design studies. The model formulation is based on the fimdarnental Consemation laws using porous electrode theory and concentrated solution theory. The model is used to estimate the difision coefficient and the kinetic parameters for the reactions at the anode and the cathode as a function of temperature. These parameters are obtained by fitting the simulated capacity and average cell voltage to experimental data over a wide range of temperatures (-55 to 49"C) and discharge loads (10 to 250 ohms). The experiments were performed on D-sized, cathode-limited, spirally wound lithium/thionyl chloride cells. The model is also used to study the effkct of cathode thickness on the cell capacity as a finction of temperature, and it was found that the optimum thickness for the cathode- limited design is temperature and load dependent.
Mathematical modeling of spinning elastic bodies for modal analysis.
Likins, P. W.; Barbera, F. J.; Baddeley, V.
1973-01-01
The problem of modal analysis of an elastic appendage on a rotating base is examined to establish the relative advantages of various mathematical models of elastic structures and to extract general inferences concerning the magnitude and character of the influence of spin on the natural frequencies and mode shapes of rotating structures. In realization of the first objective, it is concluded that except for a small class of very special cases the elastic continuum model is devoid of useful results, while for constant nominal spin rate the distributed-mass finite-element model is quite generally tractable, since in the latter case the governing equations are always linear, constant-coefficient, ordinary differential equations. Although with both of these alternatives the details of the formulation generally obscure the essence of the problem and permit very little engineering insight to be gained without extensive computation, this difficulty is not encountered when dealing with simple concentrated mass models.
Physical vs. Mathematical Models in Rock Mechanics
Morozov, I. B.; Deng, W.
2013-12-01
One of the less noted challenges in understanding the mechanical behavior of rocks at both in situ and lab conditions is the character of theoretical approaches being used. Currently, the emphasis is made on spatial averaging theories (homogenization and numerical models of microstructure), empirical models for temporal behavior (material memory, compliance functions and complex moduli), and mathematical transforms (Laplace and Fourier) used to infer the Q-factors and 'relaxation mechanisms'. In geophysical applications, we have to rely on such approaches for very broad spatial and temporal scales which are not available in experiments. However, the above models often make insufficient use of physics and utilize, for example, the simplified 'correspondence principle' instead of the laws of viscosity and friction. As a result, the commonly-used time- and frequency dependent (visco)elastic moduli represent apparent properties related to the measurement procedures and not necessarily to material properties. Predictions made from such models may therefore be inaccurate or incorrect when extrapolated beyond the lab scales. To overcome the above challenge, we need to utilize the methods of micro- and macroscopic mechanics and thermodynamics known in theoretical physics. This description is rigorous and accurate, uses only partial differential equations, and allows straightforward numerical implementations. One important observation from the physical approach is that the analysis should always be done for the specific geometry and parameters of the experiment. Here, we illustrate these methods on axial deformations of a cylindrical rock sample in the lab. A uniform, isotropic elastic rock with a thermoelastic effect is considered in four types of experiments: 1) axial extension with free transverse boundary, 2) pure axial extension with constrained transverse boundary, 3) pure bulk expansion, and 4) axial loading harmonically varying with time. In each of these cases, an
Mathematical model and software for control of commissioning blast furnace
Spirin, N. A.; Onorin, O. P.; Shchipanov, K. A.; Lavrov, V. V.
2016-09-01
Blowing-in is a starting period of blast furnace operation after construction or major repair. The current approximation methods of blowing-in burden analysis are based on blowing-in practice of previously commissioned blast furnaces. This area is theoretically underexplored; there are no common scientifically based methods for selection of the burden composition and blast parameters. The purpose of this paper is development and scientific substantiation of the methods for selection of the burden composition and blast parameters in the blast furnace during the blowing-in period. Research methods are based on physical regularities of main processes running in the blast furnace, system analysis, and application of modern principles for development and construction of mathematical models, algorithms and software designed for automated control of complex production processes in metallurgy. As consequence of the research made by the authors the following results have been achieved: 1. A set of mathematical models for analysis of burden arrangement throughout the height of the blast furnace and for selection of optimal blast and gas dynamic parameters has been developed. 2. General principles for selection of the blowing-in burden composition and blast and gas dynamic parameters have been set up. 3. The software for the engineering and process staff of the blast furnace has been developed and introduced in the industry.
Evolvable mathematical models: A new artificial Intelligence paradigm
Grouchy, Paul
We develop a novel Artificial Intelligence paradigm to generate autonomously artificial agents as mathematical models of behaviour. Agent/environment inputs are mapped to agent outputs via equation trees which are evolved in a manner similar to Symbolic Regression in Genetic Programming. Equations are comprised of only the four basic mathematical operators, addition, subtraction, multiplication and division, as well as input and output variables and constants. From these operations, equations can be constructed that approximate any analytic function. These Evolvable Mathematical Models (EMMs) are tested and compared to their Artificial Neural Network (ANN) counterparts on two benchmarking tasks: the double-pole balancing without velocity information benchmark and the challenging discrete Double-T Maze experiments with homing. The results from these experiments show that EMMs are capable of solving tasks typically solved by ANNs, and that they have the ability to produce agents that demonstrate learning behaviours. To further explore the capabilities of EMMs, as well as to investigate the evolutionary origins of communication, we develop NoiseWorld, an Artificial Life simulation in which interagent communication emerges and evolves from initially noncommunicating EMM-based agents. Agents develop the capability to transmit their x and y position information over a one-dimensional channel via a complex, dialogue-based communication scheme. These evolved communication schemes are analyzed and their evolutionary trajectories examined, yielding significant insight into the emergence and subsequent evolution of cooperative communication. Evolved agents from NoiseWorld are successfully transferred onto physical robots, demonstrating the transferability of EMM-based AIs from simulation into physical reality.
Preservice Teachers Conceptions of Mathematics-Based Software
Kurz, Terri; Middleton, James; Yanik, H. Bahadir
2004-01-01
Preservice teachers do not feel prepared to teach mathematics using technology (Smith & Shotsberger, 2001). To address this issue, we have developed a tool-based categorization of mathematics software and used it to instruct preservice teachers. Changes in thinking that occurred as a result of the course are analyzed primarily using repertory grid…
Language-Based Prior Knowledge and Transition to Mathematics
Dogan-Dunlap, Hamide; Torres, Cristina; Chen, Fan
2005-01-01
The paper provides a college mathematics student's concept maps, definitions, and essays to support the thesis that language-based prior knowledge can influence students' cognitive processes of mathematical concepts. A group of intermediate algebra students who displayed terms mainly from the spoken language on the first and the second concept…
College Students Attitude and Mathematics Achievement Using Web Based Homework
Leong, Kwan Eu; Alexander, Nathan
2014-01-01
The goal of this study was to understand how students' attitudes were connected to their mathematics learning and achievement. This investigation of students (n = 78) and their attitudes was specific to web-based homework in developmental mathematics courses in a two-year community college located in a large urban city in the United States. A…
Mathematical Modeling of Intestinal Iron Absorption Using Genetic Programming
Colins, Andrea; Gerdtzen, Ziomara P.; Nuñez, Marco T.; Salgado, J. Cristian
2017-01-01
Iron is a trace metal, key for the development of living organisms. Its absorption process is complex and highly regulated at the transcriptional, translational and systemic levels. Recently, the internalization of the DMT1 transporter has been proposed as an additional regulatory mechanism at the intestinal level, associated to the mucosal block phenomenon. The short-term effect of iron exposure in apical uptake and initial absorption rates was studied in Caco-2 cells at different apical iron concentrations, using both an experimental approach and a mathematical modeling framework. This is the first report of short-term studies for this system. A non-linear behavior in the apical uptake dynamics was observed, which does not follow the classic saturation dynamics of traditional biochemical models. We propose a method for developing mathematical models for complex systems, based on a genetic programming algorithm. The algorithm is aimed at obtaining models with a high predictive capacity, and considers an additional parameter fitting stage and an additional Jackknife stage for estimating the generalization error. We developed a model for the iron uptake system with a higher predictive capacity than classic biochemical models. This was observed both with the apical uptake dataset used for generating the model and with an independent initial rates dataset used to test the predictive capacity of the model. The model obtained is a function of time and the initial apical iron concentration, with a linear component that captures the global tendency of the system, and a non-linear component that can be associated to the movement of DMT1 transporters. The model presented in this paper allows the detailed analysis, interpretation of experimental data, and identification of key relevant components for this complex biological process. This general method holds great potential for application to the elucidation of biological mechanisms and their key components in other complex
Deductive Nomological Model and Mathematics: Making Dissatisfaction more Satisfactory
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Daniele Molinini
2014-06-01
Full Text Available The discussion on mathematical explanation has inherited the same sense of dissatisfaction that philosophers of science expressed, in the context of scientific explanation, towards the deductive-nomological model. This model is regarded as unable to cover cases of bona fide mathematical explanations and, furthermore, it is largely ignored in the relevant literature. Surprisingly, the reasons for this ostracism are not sufficiently manifest. In this paper I explore a possible extension of the model to the case of mathematical explanations and I claim that there are at least two reasons to judge the deductive-nomological picture of explanation as inadequate in that context.
Mathematical Model of Extrinsic Blood Coagulation Cascade Dynamic System
Institute of Scientific and Technical Information of China (English)
无
2000-01-01
The blood coagulation system is very important to life. This paper presents a mathematical blood coagulation model for the extrinsic pathway. This model simulates clotting factor VIII, which plays an important role in the coagulation mechanism. The mathematical model is used to study the equilibrium stability, orbit structure, attractors and global stability behavior, with conclusions in accordance with the physiological phenomena. Moreover, the results provide information about blood related illnesses, which can be used for further study of the coagulation mechanism.
Computer-Based Mathematics Instructions for Engineering Students
Khan, Mustaq A.; Wall, Curtiss E.
1996-01-01
Almost every engineering course involves mathematics in one form or another. The analytical process of developing mathematical models is very important for engineering students. However, the computational process involved in the solution of some mathematical problems may be very tedious and time consuming. There is a significant amount of mathematical software such as Mathematica, Mathcad, and Maple designed to aid in the solution of these instructional problems. The use of these packages in classroom teaching can greatly enhance understanding, and save time. Integration of computer technology in mathematics classes, without de-emphasizing the traditional analytical aspects of teaching, has proven very successful and is becoming almost essential. Sample computer laboratory modules are developed for presentation in the classroom setting. This is accomplished through the use of overhead projectors linked to graphing calculators and computers. Model problems are carefully selected from different areas.
Directory of Open Access Journals (Sweden)
S. K. Pavlov
2014-01-01
Full Text Available Before fuelling the tanks of missiles, boosters, and spacecraft with liquid-propellant components (LPC their temperature preparation is needed. The missile-system ground equipment performs this operation during prelaunch processing of space-purpose missiles (SPM. Usually, the fuel cooling is necessary to increase its density and provide heat compensation during prelaunch operation of SPM. The fuel temperature control systems (FTCS using different principles of operation and types of coolants are applied for fuel cooling.To determine parameters of LPC cooling process through the fuel heat exchange in the heat exchanger with coolant, which is cooled by liquid nitrogen upon contact heat exchange in the coolant reservoir, a mathematical model of this process and a design technique are necessary. Both allow us to determine design parameters of the cooling system and the required liquid nitrogen reserve to cool LPC to the appropriate temperature.The article presents an overview of foreign and domestic publications on cooling processes research and implementation using cryogenic products such as liquid nitrogen. The article draws a conclusion that it is necessary to determine the parameters of LPC cooling process through the fuel heat exchange in the heat exchanger with coolant, which is liquid nitrogen-cooled upon contact heat exchange in the coolant reservoir allowing to define rational propellant cooling conditions to the specified temperature.The mathematical model describes the set task on the assumption that a heat exchange between the LPC and the coolant in the heat exchanger and with the environment through the walls of tanks and pipelines of circulation loops is quasi-stationary.The obtained curves allow us to calculate temperature changes of LPC and coolant, cooling time and liquid nitrogen consumption, depending on the process parameters such as a flow rate of liquid nitrogen, initial coolant temperature, pump characteristics, thermal
Illustrations of mathematical modeling in biology: epigenetics, meiosis, and an outlook.
Richards, D; Berry, S; Howard, M
2012-01-01
In the past few years, mathematical modeling approaches in biology have begun to fulfill their promise by assisting in the dissection of complex biological systems. Here, we review two recent examples of predictive mathematical modeling in plant biology. The first involves the quantitative epigenetic silencing of the floral repressor gene FLC in Arabidopsis, mediated by a Polycomb-based system. The second involves the spatiotemporal dynamics of telomere bouquet formation in wheat-rye meiosis. Although both the biology and the modeling framework of the two systems are different, both exemplify how mathematical modeling can help to accelerate discovery of the underlying mechanisms in complex biological systems. In both cases, the models that developed were relatively minimal, including only essential features, but both nevertheless yielded fundamental insights. We also briefly review the current state of mathematical modeling in biology, difficulties inherent in its application, and its potential future development.
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Alan E Bilsland
2014-02-01
Full Text Available Cancer cells depend on transcription of telomerase reverse transcriptase (TERT. Many transcription factors affect TERT, though regulation occurs in context of a broader network. Network effects on telomerase regulation have not been investigated, though deeper understanding of TERT transcription requires a systems view. However, control over individual interactions in complex networks is not easily achievable. Mathematical modelling provides an attractive approach for analysis of complex systems and some models may prove useful in systems pharmacology approaches to drug discovery. In this report, we used transfection screening to test interactions among 14 TERT regulatory transcription factors and their respective promoters in ovarian cancer cells. The results were used to generate a network model of TERT transcription and to implement a dynamic Boolean model whose steady states were analysed. Modelled effects of signal transduction inhibitors successfully predicted TERT repression by Src-family inhibitor SU6656 and lack of repression by ERK inhibitor FR180204, results confirmed by RT-QPCR analysis of endogenous TERT expression in treated cells. Modelled effects of GSK3 inhibitor 6-bromoindirubin-3'-oxime (BIO predicted unstable TERT repression dependent on noise and expression of JUN, corresponding with observations from a previous study. MYC expression is critical in TERT activation in the model, consistent with its well known function in endogenous TERT regulation. Loss of MYC caused complete TERT suppression in our model, substantially rescued only by co-suppression of AR. Interestingly expression was easily rescued under modelled Ets-factor gain of function, as occurs in TERT promoter mutation. RNAi targeting AR, JUN, MXD1, SP3, or TP53, showed that AR suppression does rescue endogenous TERT expression following MYC knockdown in these cells and SP3 or TP53 siRNA also cause partial recovery. The model therefore successfully predicted several
Mathematical modeling of urea transport in the kidney.
Layton, Anita T
2014-01-01
Mathematical modeling techniques have been useful in providing insights into biological systems, including the kidney. This article considers some of the mathematical models that concern urea transport in the kidney. Modeling simulations have been conducted to investigate, in the context of urea cycling and urine concentration, the effects of hypothetical active urea secretion into pars recta. Simulation results suggest that active urea secretion induces a "urea-selective" improvement in urine concentrating ability. Mathematical models have also been built to study the implications of the highly structured organization of tubules and vessels in the renal medulla on urea sequestration and cycling. The goal of this article is to show how physiological problems can be formulated and studied mathematically, and how such models may provide insights into renal functions.
Modelling Of Flotation Processes By Classical Mathematical Methods - A Review
Jovanović, Ivana; Miljanović, Igor
2015-12-01
Flotation process modelling is not a simple task, mostly because of the process complexity, i.e. the presence of a large number of variables that (to a lesser or a greater extent) affect the final outcome of the mineral particles separation based on the differences in their surface properties. The attempts toward the development of the quantitative predictive model that would fully describe the operation of an industrial flotation plant started in the middle of past century and it lasts to this day. This paper gives a review of published research activities directed toward the development of flotation models based on the classical mathematical rules. The description and systematization of classical flotation models were performed according to the available references, with emphasize exclusively given to the flotation process modelling, regardless of the model application in a certain control system. In accordance with the contemporary considerations, models were classified as the empirical, probabilistic, kinetic and population balance types. Each model type is presented through the aspects of flotation modelling at the macro and micro process levels.
Introduction to mathematical biology modeling, analysis, and simulations
Chou, Ching Shan
2016-01-01
This book is based on a one semester course that the authors have been teaching for several years, and includes two sets of case studies. The first includes chemostat models, predator-prey interaction, competition among species, the spread of infectious diseases, and oscillations arising from bifurcations. In developing these topics, readers will also be introduced to the basic theory of ordinary differential equations, and how to work with MATLAB without having any prior programming experience. The second set of case studies were adapted from recent and current research papers to the level of the students. Topics have been selected based on public health interest. This includes the risk of atherosclerosis associated with high cholesterol levels, cancer and immune interactions, cancer therapy, and tuberculosis. Readers will experience how mathematical models and their numerical simulations can provide explanations that guide biological and biomedical research. Considered to be the undergraduate companion to t...
Mathematical model of innovative sustainability “green” construction object
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Slesarev Michail
2016-01-01
Full Text Available The paper addresses the issue of finding sustainability of “green” innovative processes in interaction between construction activities and the environment. The problem of today’s construction science is stated as comprehensive integration and automation of natural and artificial intellects within systems that ensure environmental safety of construction based on innovative sustainability of “green” technologies in the life environment, and “green” innovative products. The suggested solution to the problem should formalize sustainability models and methods for interpretation of optimization mathematical modeling problems respective to problems of environmental-based innovative process management, adapted to construction of “green” objects, “green” construction technologies, “green” innovative materials and structures.
Nonlinear mathematical modeling and sensitivity analysis of hydraulic drive unit
Kong, Xiangdong; Yu, Bin; Quan, Lingxiao; Ba, Kaixian; Wu, Liujie
2015-09-01
The previous sensitivity analysis researches are not accurate enough and also have the limited reference value, because those mathematical models are relatively simple and the change of the load and the initial displacement changes of the piston are ignored, even experiment verification is not conducted. Therefore, in view of deficiencies above, a nonlinear mathematical model is established in this paper, including dynamic characteristics of servo valve, nonlinear characteristics of pressure-flow, initial displacement of servo cylinder piston and friction nonlinearity. The transfer function block diagram is built for the hydraulic drive unit closed loop position control, as well as the state equations. Through deriving the time-varying coefficient items matrix and time-varying free items matrix of sensitivity equations respectively, the expression of sensitivity equations based on the nonlinear mathematical model are obtained. According to structure parameters of hydraulic drive unit, working parameters, fluid transmission characteristics and measured friction-velocity curves, the simulation analysis of hydraulic drive unit is completed on the MATLAB/Simulink simulation platform with the displacement step 2 mm, 5 mm and 10 mm, respectively. The simulation results indicate that the developed nonlinear mathematical model is sufficient by comparing the characteristic curves of experimental step response and simulation step response under different constant load. Then, the sensitivity function time-history curves of seventeen parameters are obtained, basing on each state vector time-history curve of step response characteristic. The maximum value of displacement variation percentage and the sum of displacement variation absolute values in the sampling time are both taken as sensitivity indexes. The sensitivity indexes values above are calculated and shown visually in histograms under different working conditions, and change rules are analyzed. Then the sensitivity
MATHEMATICAL MODELING OF INFRARED MILK PASTEURIZATION
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S. T. Antipov
2013-01-01
Full Text Available Based on the model representation of the process of pasteurization of milk infrared patterns of change in temperature of the product in the heating zone with the heat flows of different nature were obtained. The changes in the basic performance of the quartz oscillator during operation were also obtained.
Mathematical Modelling of Fluid Flow in Cone and Cavitation Formation
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Milada KOZUBKOVÁ
2011-06-01
Full Text Available Problem of cavitation is the undesirable phenomena occuring in the fluid flow in many hydraulic application (pumps, turbines, valves, etc.. Therefore this is in the focus of interest using experimental and mathematical methods. Based on cavitation modelling in Laval nozzle results and experience [1], [2], [4], following problem described as the water flow at the outlet from turbine blade wheel was solved. Primarily the problem is simplified into modelling of water flow in cone. Profiles of axial, radial and tangential velocity are defined on inlet zone. The value of pressure is defined on the outlet. Boundary conditions were defined by main investigator of the grant project – Energy Institute, Victor Kaplan’s Department of Fluid Engineering, Faculty of Mechanical Engineering, Brno University of Technology. The value of air volume was insignificant. Cavitation was solved by Singhal model of cavitation.
Mathematical Modelling of Unmanned Aerial Vehicles with Four Rotors
Directory of Open Access Journals (Sweden)
Zoran Benić
2016-01-01
Full Text Available Mathematical model of an unmanned aerial vehicle with four propulsors (quadcopter is indispensable in quadcopter movement simulation and later modelling of the control algorithm. Mathematical model is, at the same time, the first step in comprehending the mathematical principles and physical laws which are applied to the quadcopter system. The objective is to define the mathematical model which will describe the quadcopter behavior with satisfactory accuracy and which can be, with certain modifications, applicable for the similar configurations of multirotor aerial vehicles. At the beginning of mathematical model derivation, coordinate systems are defined and explained. By using those coordinate systems, relations between parameters defined in the earth coordinate system and in the body coordinate system are defined. Further, the quadcopter kinematic is described which enables setting those relations. Also, quadcopter dynamics is used to introduce forces and torques to the model through usage of Newton-Euler method. Final derived equation is Newton’s second law in the matrix notation. For the sake of model simplification, hybrid coordinate system is defined, and quadcopter dynamic equations derived with the respect to it. Those equations are implemented in the simulation. Results of behavior of quadcopter mathematical model are graphically shown for four cases. For each of the cases the propellers revolutions per minute (RPM are set in a way that results in the occurrence of the controllable variables which causes one of four basic quadcopter movements in space.
Mathematical modelling with case studies using Maple and Matlab
Barnes, B
2014-01-01
Introduction to Mathematical ModelingMathematical models An overview of the book Some modeling approaches Modeling for decision makingCompartmental Models Introduction Exponential decay and radioactivity Case study: detecting art forgeries Case study: Pacific rats colonize New Zealand Lake pollution models Case study: Lake Burley Griffin Drug assimilation into the blood Case study: dull, dizzy, or dead? Cascades of compartments First-order linear DEs Equilibrium points and stability Case study: money, money, money makes the world go aroundModels of Single PopulationsExponential growth Density-
Mathematical Modeling of Bacteria Communication in Continuous Cultures
Directory of Open Access Journals (Sweden)
Maria Vittoria Barbarossa
2016-05-01
Full Text Available Quorum sensing is a bacterial cell-to-cell communication mechanism and is based on gene regulatory networks, which control and regulate the production of signaling molecules in the environment. In the past years, mathematical modeling of quorum sensing has provided an understanding of key components of such networks, including several feedback loops involved. This paper presents a simple system of delay differential equations (DDEs for quorum sensing of Pseudomonas putida with one positive feedback plus one (delayed negative feedback mechanism. Results are shown concerning fundamental properties of solutions, such as existence, uniqueness, and non-negativity; the last feature is crucial for mathematical models in biology and is often violated when working with DDEs. The qualitative behavior of solutions is investigated, especially the stationary states and their stability. It is shown that for a certain choice of parameter values, the system presents stability switches with respect to the delay. On the other hand, when the delay is set to zero, a Hopf bifurcation might occur with respect to one of the negative feedback parameters. Model parameters are fitted to experimental data, indicating that the delay system is sufficient to explain and predict the biological observations.
System and mathematical modeling of quadrotor dynamics
Goodman, Jacob M.; Kim, Jinho; Gadsden, S. Andrew; Wilkerson, Stephen A.
2015-05-01
Unmanned aerial systems (UAS) are becoming increasingly visible in our daily lives; and range in operation from search and rescue, monitoring hazardous environments, and to the delivery of goods. One of the most popular UAS are based on a quad-rotor design. These are typically small devices that rely on four propellers for lift and movement. Quad-rotors are inherently unstable, and rely on advanced control methodologies to keep them operating safely and behaving in a predictable and desirable manner. The control of these devices can be enhanced and improved by making use of an accurate dynamic model. In this paper, we examine a simple quadrotor model, and note some of the additional dynamic considerations that were left out. We then compare simulation results of the simple model with that of another comprehensive model.
Key Concept Mathematics and Management Science Models
Macbeth, Thomas G.; Dery, George C.
1973-01-01
The presentation of topics in calculus and matrix algebra to second semester freshmen along with a treatment of exponential and power functions would permit them to cope with a significant portion of the mathematical concepts that comprise the essence of several disciplines in a business school curriculum. (Author)
Vasechkina, E. F.; Kazankova, I. I.
2014-11-01
A mathematical model simulating the growth and development of the mussel Mytilus galloprovincialis Lam. on artificial substrates has been constructed. The model is based on experimental data and contains mathematical descriptions of the filtration, respiration, excretion, spawning, and growth of an individual during its ontogenesis from the moment it attaches to a solid substrate to the attainment of a marketable size. The test computations have been compared to the available observation data for mussel farms.
Mathematical and numerical foundations of turbulence models and applications
Chacón Rebollo, Tomás
2014-01-01
With applications to climate, technology, and industry, the modeling and numerical simulation of turbulent flows are rich with history and modern relevance. The complexity of the problems that arise in the study of turbulence requires tools from various scientific disciplines, including mathematics, physics, engineering, and computer science. Authored by two experts in the area with a long history of collaboration, this monograph provides a current, detailed look at several turbulence models from both the theoretical and numerical perspectives. The k-epsilon, large-eddy simulation, and other models are rigorously derived and their performance is analyzed using benchmark simulations for real-world turbulent flows. Mathematical and Numerical Foundations of Turbulence Models and Applications is an ideal reference for students in applied mathematics and engineering, as well as researchers in mathematical and numerical fluid dynamics. It is also a valuable resource for advanced graduate students in fluid dynamics,...
RECENT MATHEMATICAL STUDIES IN THE MODELING OF OPTICS AND ELECTROMAGNETICS
Institute of Scientific and Technical Information of China (English)
Gang Bao
2004-01-01
This work is concerned with mathematical modeling, analysis, and computation of optics and electromagnetics, motivated particularly by optical and microwave applications.The main technical focus is on Maxwell's equations in complex linear and nonlinear media.
A Local Mathematical Model for EPR-Experiments
Philipp, W.; Hess, K.
2002-01-01
In this paper we give a detailed and simplified version of our original mathematical model published first in the Proceedings of the National Academy of Science. We hope that this will clarify some misinterpretations of our original paper.
Mathematical modeling of electromechanical processes in a brushless DC motor
Directory of Open Access Journals (Sweden)
V.I. Tkachuk
2014-03-01
Full Text Available On the basis of initial assumptions, a mathematical model that describes electromechanical processes in a brushless DC electric motor with a salient-pole stator and permanent-magnet excitation is created.
The Mathematical Concept of Set and the 'Collection' Model.
Fischbein, Efraim; Baltsan, Madlen
1999-01-01
Hypothesizes that various misconceptions held by students with regard to the mathematical set concept may be explained by the initial collection model. Study findings confirm the hypothesis. (Author/ASK)
Science modelling in pre-calculus: how to make mathematics problems contextually meaningful
Sokolowski, Andrzej; Yalvac, Bugrahan; Loving, Cathleen
2011-04-01
'Use of mathematical representations to model and interpret physical phenomena and solve problems is one of the major teaching objectives in high school math curriculum' (National Council of Teachers of Mathematics (NCTM), Principles and Standards for School Mathematics, NCTM, Reston, VA, 2000). Commonly used pre-calculus textbooks provide a wide range of application problems. However, these problems focus students' attention on evaluating or solving pre-arranged formulas for given values. The role of scientific content is reduced to provide a background for these problems instead of being sources of data gathering for inducing mathematical tools. Students are neither required to construct mathematical models based on the contexts nor are they asked to validate or discuss the limitations of applied formulas. Using these contexts, the instructor may think that he/she is teaching problem solving, where in reality he/she is teaching algorithms of the mathematical operations (G. Kulm (ed.), New directions for mathematics assessment, in Assessing Higher Order Thinking in Mathematics, Erlbaum, Hillsdale, NJ, 1994, pp. 221-240). Without a thorough representation of the physical phenomena and the mathematical modelling processes undertaken, problem solving unintentionally appears as simple algorithmic operations. In this article, we deconstruct the representations of mathematics problems from selected pre-calculus textbooks and explicate their limitations. We argue that the structure and content of those problems limits students' coherent understanding of mathematical modelling, and this could result in weak student problem-solving skills. Simultaneously, we explore the ways to enhance representations of those mathematical problems, which we have characterized as lacking a meaningful physical context and limiting coherent student understanding. In light of our discussion, we recommend an alternative to strengthen the process of teaching mathematical modelling - utilization
A mathematical look at a physical power prediction model
DEFF Research Database (Denmark)
Landberg, L.
1998-01-01
This article takes a mathematical look at a physical model used to predict the power produced from wind farms. The reason is to see whether simple mathematical expressions can replace the original equations and to give guidelines as to where simplifications can be made and where they cannot....... The article shows that there is a linear dependence between the geostrophic wind and the local wind at the surface, but also that great care must be taken in the selection of the simple mathematical models, since physical dependences play a very important role, e.g. through the dependence of the turning...
Mathematical Modeling of Neuro-Vascular Coupling in Rat Cerebellum
DEFF Research Database (Denmark)
Rasmussen, Tina
measured field potential is used as an indicator of neuronal activity, and the cortical blood flow is measured by means of laser-Doppler flowmetry. Using system identification methods, these measurements have been used to construct and validate parametric mathematical models of the neuro-vascular system....... Mathematical arguments as well as hypotheses about the physiological system have been used to construct the models.......Activity in the neurons called climbing fibers causes blood flow changes. But the physiological mechanisms which mediate the coupling are not well understood. This PhD thesis investigates the mechanisms of neuro-vascular coupling by means of mathematical methods. In experiments, the extracellularly...
[Mathematical models of decision making and learning].
Ito, Makoto; Doya, Kenji
2008-07-01
Computational models of reinforcement learning have recently been applied to analysis of brain imaging and neural recording data to identity neural correlates of specific processes of decision making, such as valuation of action candidates and parameters of value learning. However, for such model-based analysis paradigms, selecting an appropriate model is crucial. In this study we analyze the process of choice learning in rats using stochastic rewards. We show that "Q-learning," which is a standard reinforcement learning algorithm, does not adequately reflect the features of choice behaviors. Thus, we propose a generalized reinforcement learning (GRL) algorithm that incorporates the negative reward effect of reward loss and forgetting of values of actions not chosen. Using the Bayesian estimation method for time-varying parameters, we demonstrated that the GRL algorithm can predict an animal's choice behaviors as efficiently as the best Markov model. The results suggest the usefulness of the GRL for the model-based analysis of neural processes involved in decision making.
The mathematical model realization algorithm of high voltage cable
2006-01-01
At mathematical model realization algorithm is very important to know the account order of necessary relations and how it presents. Depending of loads or signal sources connection in selected points of mathematical model its very important to know as to make the equations in this point that it was possible to determine all unknown variables in this point. The number of equations which describe this point must to coincide with number of unknown variables, and matrix which describes factor...
Mathematical and computational modeling in biology at multiple scales
Tuszynski, Jack A; Winter, Philip; White, Diana; Tseng, Chih-Yuan; Sahu, Kamlesh K.; Gentile, Francesco; Spasevska, Ivana; Omar, Sara Ibrahim; Nayebi, Niloofar; Churchill, Cassandra DM; Klobukowski, Mariusz; El-Magd, Rabab M Abou
2014-01-01
A variety of topics are reviewed in the area of mathematical and computational modeling in biology, covering the range of scales from populations of organisms to electrons in atoms. The use of maximum entropy as an inference tool in the fields of biology and drug discovery is discussed. Mathematical and computational methods and models in the areas of epidemiology, cell physiology and cancer are surveyed. The technique of molecular dynamics is covered, with special attention to force fields f...
Mathematical modelling and numerical simulation of oil pollution problems
2015-01-01
Written by outstanding experts in the fields of marine engineering, atmospheric physics and chemistry, fluid dynamics and applied mathematics, the contributions in this book cover a wide range of subjects, from pure mathematics to real-world applications in the oil spill engineering business. Offering a truly interdisciplinary approach, the authors present both mathematical models and state-of-the-art numerical methods for adequately solving the partial differential equations involved, as well as highly practical experiments involving actual cases of ocean oil pollution. It is indispensable that different disciplines of mathematics, like analysis and numerics, together with physics, biology, fluid dynamics, environmental engineering and marine science, join forces to solve today’s oil pollution problems. The book will be of great interest to researchers and graduate students in the environmental sciences, mathematics and physics, showing the broad range of techniques needed in order to solve these poll...
Mathematical models of ecology and evolution
DEFF Research Database (Denmark)
Zhang, Lai
2012-01-01
dynamics but as a trade-o promotes species survival by shortening juvenile delay between birth and the onset of reproduction. Paper II compares the size-spectrum and food-web representations of communities using two traits (body size and habitat location) based unstructured population model of Lotka......) based size-structured population model, that is, interference in foraging, maintenance, survival, and recruitment. Their impacts on the ecology and evolution of size-structured populations and communities are explored. Ecologically, interference aects population demographic properties either negatively...... or positively, depending on the balance between interference induced gain and cost. Evolutionarily, the maturation size is either depressed (interference in foraging and maintenance) or elevated (interference in survival and recruitment) in a monomorphic population environment. Moreover, among the four...
Mathematic modeling on flexible cooling system in hot strip mill
Institute of Scientific and Technical Information of China (English)
彭良贵; 刘相华; 赵宪明; 吴迪
2014-01-01
A novel cooling system combining ultra fast cooling rigs with laminar cooling devices was investigated. Based on the different cooling mechanisms, a serial of mathematic models were established to describe the relationship between water flow and spraying pressure and the relationship between water spraying heat flux and layout of nozzles installed on the top and bottom cooling headers. Model parameters were validated by measured data. Heat transfer models including air convection model, heat radiation model and water cooling capacity model were detailedly introduced. In addition, effects on cooling capacity by water temperature and different valve patterns were also presented. Finally, the comparison results from UFC used or not have been provided with respect to temperature evolution and mechanical properties of Q235B steel grade with thickness of 7.8 mm. Since online application of the sophisticated CTC process control system based on these models, run-out table cooling control system has been running stably and reliably to produce resource-saving, low-cost steels with smaller grain size.
Voltammetry: mathematical modelling and Inverse Problem
Koshev, N A; Kuzina, V V
2016-01-01
We propose the fast semi-analytical method of modelling the polarization curves in the voltammetric experiment. The method is based on usage of the special func- tions and shows a big calculation speed and a high accuracy and stability. Low computational needs of the proposed algorithm allow us to state the set of Inverse Problems of voltammetry for the reconstruction of metal ions concentrations or the other parameters of the electrolyte under investigation.
Some Aspects of Mathematical Model of Collaborative Learning
Nakamura, Yasuyuki; Yasutake, Koichi; Yamakawa, Osamu
2012-01-01
There are some mathematical learning models of collaborative learning, with which we can learn how students obtain knowledge and we expect to design effective education. We put together those models and classify into three categories; model by differential equations, so-called Ising spin and a stochastic process equation. Some of the models do not…
APPLICATION OF GIS AND MATHEMATICAL MODELING IN MARITIME CRISIS SITUATIONS
Directory of Open Access Journals (Sweden)
Nenad Mladineo
2010-12-01
Full Text Available This paper aims to propose a decision support system for maritime crisis situation, due to fact that Croatia has decided to implement Directive 2002/59/EC to define places of refuge for ships in need of assistance off their coasts, or to develop techniques for providing assistance to such ships. In order to fulfill this Directive it is necessary to build an effective Decision Support System (DSS based on GIS and mathematical modeling. The basic module of the proposed system is GIS, for all levels of DSS, that comprise information subsystems about spatial and other data and serves the other modules with data and information. Starting points for analysis are shipping corridors, and 380 potential locations for places of refuge designated in the official navigational pilot book. Multicriteria analysis, with GIS-generated input data, has been used to establish "worthiness" of a place of refuge for each ship category, taking into account kinds of accident. Proposed mathematical models facilitate optimal usage of "available intervention resources".
Mathematical models for foam-diverted acidizing and their applications
Institute of Scientific and Technical Information of China (English)
Li Songyan; Li Zhaomin; Lin Riyi
2008-01-01
Foam diversion can effectively solve the problem of uneven distribution of acid in layers of different permeabilities during matrix acidizing.Based on gas trapping theory and the mass conservation equation,mathematical models were developed for foam-diverted acidizing,which can be achieved by a foam slug followed by acid injection or by continuous injection of foamed acid.The design method for foam-diverted acidizing was also given.The mathematical models were solved by a computer program.Computed results show that the total formation skin factor,wellhead pressure and bottomhole pressure increase with foam injection,but decrease with acid injection.Volume flow rate in a highpermeability layer decreases,while that in a low-permeability layer increases,thus diverting acid to the low-permeability layer from the high-permeability layer.Under the same formation conditions,for foamed acid treatment the operation was longer,and wellhead and bottomhole pressures are higher.Field application shows that foam slug can effectively block high permeability layers,and improve intake profile noticeably.
MATHEMATICAL MODEL SUGGESTED FOR THE STUDY OF THE KNEE MECHANICS
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Marius GRĂMADĂ
2012-07-01
Full Text Available Knowing the operated the knee biomechanical behavior is important during the life of the endoprosthesis,lifestyle changes and medical rehabilitation. One of the main causes of failure of a primary total prosthetic knee joint isthe instability. From the moment of its implantation, the endoprosthesis is subjected to external forces, which tend todestabilize it, while the muscles and pericapsulare ligaments oppose it. Theoretically there is a relationship between theexternal disturbing force, respectively ligament tension and the knee frontal plane deviation. The purpose of this paperis to test several mathematical models describing the biomechanical behavior of knee ligaments in relation todeviation. On a group of 39 patients we measured the torque of the joint capsule in relation to the deviation using apressure sensor tensor and a torque screwdriver, and we analyzed these data using a statistical program. We havedemonstrated the existence of this relationship as a function of degree 2 and we made predictions based on itcalculating ligament torque and ligament stiffness at 0 and 5 degrees of deviation. The conclusion of this study showsthat there is a strong relationship between ligament torque and deviation knee, which can be described mathematically.This model can be used to study the knee operated and improve the prosthetic devices.
Mathematical modelling methodologies in predictive food microbiology: a SWOT analysis.
Ferrer, Jordi; Prats, Clara; López, Daniel; Vives-Rego, Josep
2009-08-31
Predictive microbiology is the area of food microbiology that attempts to forecast the quantitative evolution of microbial populations over time. This is achieved to a great extent through models that include the mechanisms governing population dynamics. Traditionally, the models used in predictive microbiology are whole-system continuous models that describe population dynamics by means of equations applied to extensive or averaged variables of the whole system. Many existing models can be classified by specific criteria. We can distinguish between survival and growth models by seeing whether they tackle mortality or cell duplication. We can distinguish between empirical (phenomenological) models, which mathematically describe specific behaviour, and theoretical (mechanistic) models with a biological basis, which search for the underlying mechanisms driving already observed phenomena. We can also distinguish between primary, secondary and tertiary models, by examining their treatment of the effects of external factors and constraints on the microbial community. Recently, the use of spatially explicit Individual-based Models (IbMs) has spread through predictive microbiology, due to the current technological capacity of performing measurements on single individual cells and thanks to the consolidation of computational modelling. Spatially explicit IbMs are bottom-up approaches to microbial communities that build bridges between the description of micro-organisms at the cell level and macroscopic observations at the population level. They provide greater insight into the mesoscale phenomena that link unicellular and population levels. Every model is built in response to a particular question and with different aims. Even so, in this research we conducted a SWOT (Strength, Weaknesses, Opportunities and Threats) analysis of the different approaches (population continuous modelling and Individual-based Modelling), which we hope will be helpful for current and future
Eringen, A Cemal
2013-01-01
Continuum Physics: Volume 1 - Mathematics is a collection of papers that discusses certain selected mathematical methods used in the study of continuum physics. Papers in this collection deal with developments in mathematics in continuum physics and its applications such as, group theory functional analysis, theory of invariants, and stochastic processes. Part I explains tensor analysis, including the geometry of subspaces and the geometry of Finsler. Part II discusses group theory, which also covers lattices, morphisms, and crystallographic groups. Part III reviews the theory of invariants th
Full-Range Mathematical Modeling of Turboshaft Engine in Aerospace
Sheng, Hanlin; Zhang, Tianhong; Jiang, Wei
2016-12-01
In this paper, an approximate computation method of low-speed component characteristics in aeroengine is used and full-range component characteristics is obtained by combining experimental data above idle. Moreover, based on components matching method and variable specific heat method, a full-range static and dynamic mathematical model of turboshaft engine is built, including start-up state. And the numerical simulation result of the engine whole working process is also showed in this paper. The comparison result between the simulation result and the experimental data shows that, the full-range model built by the computation method of low-speed component characteristics is of a certain accuracy, which can meet the needs of a turboshaft engine semi-physical simulation.
Alzheimer's disease: a mathematical model for onset and progression
Bertsch, Michiel; Marcello, Norina; Tesi, Maria Carla; Tosin, Andrea
2015-01-01
In this paper we propose a mathematical model for the onset and progression of Alzheimer's disease based on transport and diffusion equations. We regard brain neurons as a continuous medium, and structure them by their degree of malfunctioning. Two different mechanisms are assumed to be relevant for the temporal evolution of the disease: i) diffusion and agglomeration of soluble polymers of amyloid, produced by damaged neurons; ii) neuron-to-neuron prion-like transmission. We model these two processes by a system of Smoluchowski equations for the amyloid concentration, coupled to a kinetic-type transport equation for the distribution function of the degree of malfunctioning of neurons. The second equation contains an integral term describing the random onset of the disease as a jump process localized in particularly sensitive areas of the brain. Even though we deliberately neglect many aspects of the complexity of the brain and the disease, numerical simulations are in good qualitative agreement with clinical...
Mathematical models for suspension bridges nonlinear structural instability
Gazzola, Filippo
2015-01-01
This work provides a detailed and up-to-the-minute survey of the various stability problems that can affect suspension bridges. In order to deduce some experimental data and rules on the behavior of suspension bridges, a number of historical events are first described, in the course of which several questions concerning their stability naturally arise. The book then surveys conventional mathematical models for suspension bridges and suggests new nonlinear alternatives, which can potentially supply answers to some stability questions. New explanations are also provided, based on the nonlinear structural behavior of bridges. All the models and responses presented in the book employ the theory of differential equations and dynamical systems in the broader sense, demonstrating that methods from nonlinear analysis can allow us to determine the thresholds of instability.
Mathematical modelling of unglazed solar collectors under extreme operating conditions
DEFF Research Database (Denmark)
Bunea, M.; Perers, Bengt; Eicher, S.
2015-01-01
average temperature levels at the evaporator. Simulation of these systems requires a collector model that can take into account operation at very low temperatures (below freezing) and under various weather conditions, particularly operation without solar irradiation.A solar collector mathematical model......Combined heat pumps and solar collectors got a renewed interest on the heating system market worldwide. Connected to the heat pump evaporator, unglazed solar collectors can considerably increase their efficiency, but they also raise the coefficient of performance of the heat pump with higher...... was found due to the condensation phenomenon and up to 40% due to frost under no solar irradiation. This work also points out the influence of the operating conditions on the collector's characteristics.Based on experiments carried out at a test facility, every heat flux on the absorber was separately...
Innovative mathematical modeling in environmental remediation
Energy Technology Data Exchange (ETDEWEB)
Yeh, Gour T. [Taiwan Typhoon and Flood Research Institute (Taiwan); National Central Univ. (Taiwan); Univ. of Central Florida (United States); Gwo, Jin Ping [Nuclear Regulatory Commission (NRC), Rockville, MD (United States); Siegel, Malcolm D. [Sandia National Laboratories, Albuquerque, NM (United States); Li, Ming-Hsu [National Central Univ. (Taiwan); ; Fang, Yilin [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States); Zhang, Fan [Inst. of Tibetan Plateau Research, Chinese Academy of Sciences (China); Luo, Wensui [Inst. of Tibetan Plateau Research, Chinese Academy of Sciences (China); Yabusaki, Steven B. [Pacific Northwest National Laboratory (PNNL), Richland, WA (United States)
2013-05-01
There are two different ways to model reactive transport: ad hoc and innovative reaction-based approaches. The former, such as the Kd simplification of adsorption, has been widely employed by practitioners, while the latter has been mainly used in scientific communities for elucidating mechanisms of biogeochemical transport processes. It is believed that innovative mechanistic-based models could serve as protocols for environmental remediation as well. This paper reviews the development of a mechanistically coupled fluid flow, thermal transport, hydrologic transport, and reactive biogeochemical model and example-applications to environmental remediation problems. Theoretical bases are sufficiently described. Four example problems previously carried out are used to demonstrate how numerical experimentation can be used to evaluate the feasibility of different remediation approaches. The first one involved the application of a 56-species uranium tailing problem to the Melton Branch Subwatershed at Oak Ridge National Laboratory (ORNL) using the parallel version of the model. Simulations were made to demonstrate the potential mobilization of uranium and other chelating agents in the proposed waste disposal site. The second problem simulated laboratory-scale system to investigate the role of natural attenuation in potential off-site migration of uranium from uranium mill tailings after restoration. It showed inadequacy of using a single Kd even for a homogeneous medium. The third example simulated laboratory experiments involving extremely high concentrations of uranium, technetium, aluminum, nitrate, and toxic metals (e.g.,Ni, Cr, Co).The fourth example modeled microbially-mediated immobilization of uranium in an unconfined aquifer using acetate amendment in a field-scale experiment. The purposes of these modeling studies were to simulate various mechanisms of mobilization and immobilization of radioactive wastes and to illustrate how to apply reactive transport models
Michelsen, Claus
2015-01-01
Mathematics plays a crucial role in physics. This role is brought about predominantly through the building, employment, and assessment of mathematical models, and teachers and educators should capture this relationship in the classroom in an effort to improve students' achievement and attitude in both physics and mathematics. But although there…
The development of mathematical creativity through model-eliciting activities
Directory of Open Access Journals (Sweden)
Helena M. Wessels
2012-03-01
Full Text Available The ability to think creatively and solve problems is regarded as crucial for economic and personal success. The traditional approach in classrooms is not conducive to mathematical creativity, and prospective teachers should be exposed to alternative problem solving activities through which mathematical knowledge, competencies and creativity can be developed. Research studies have pointed out the possibilities and successes of a modelling approach in which complex, open problems or model-eliciting problems are used to develop meaningful mathematical knowledge and prepare learners for everyday life, as well as for tertiary studies and their occupations. Model-eliciting activities (MEAs do not only develop mathematical knowledge, but also creativity. Five hundred and one preservice Foundation Phase teachers completed different model-eliciting activities (MEAs in a longitudinal project over a period of two years. The purpose was to develop and consolidate their own mathematical knowledge, and at the same time develop creativity and modelling competencies. The ultimate purpose of the project is to prepare preservice teachers to use mathematical modelling to develop creativity in young children aged six to nine. Through solving MEAs learners also build and consolidate their mathematical knowledge and improve their own problem-solving abilities. A framework with four criteria for the identification of creativity was successfully used to evaluate levels of creativity in the solutions offered to the MEAs. Preservice teachers’ final models displayed reasonably consistent levels of creativity regarding the four criteria. Their willingness to solve MEAs and create multiple, original and useful – therefore creative – solutions also increased over the period of their exposure to modelling tasks.
Energy Technology Data Exchange (ETDEWEB)
Zhou Tao [Department of Thermal Engineering, Tsinghua University, Beijing 100084 (China)]. E-mail: zhoutao@mail.tsinghua.edu.cn; Wang Zenghui [Department of Engineering Mechanics, Tsinghua University, Beijing 100084 (China); Yang Ruichang [Department of Thermal Engineering, Tsinghua University, Beijing 100084 (China)
2005-10-01
Experiment data got from onset of nucleate boiling (ONB) in natural circulation is analyzed using unascertained mathematics. Unitary mathematics model of the relation between the temperature and onset of nucleate boiling is built up to analysis ONB. Multiple unascertained mathematics models are also built up with the onset of natural circulation boiling equation based on the experiment. Unascertained mathematics makes that affirmative results are a range of numbers that reflect the fluctuation of experiment data more truly. The fluctuating value with the distribution function F(x) is the feature of unascertained mathematics model and can express fluctuating experimental data. Real status can be actually described through using unascertained mathematics. Thus, for calculation of ONB point, the description of unascertained mathematics model is more precise than common mathematics model. Based on the unascertained mathematics, a new ONB model is developed, which is important for advanced reactor safety analysis. It is conceivable that the unascertained mathematics could be applied to many other two-phase measurements as well.
Rusu-Anghel, S.
2017-01-01
Analytical modeling of the flow of manufacturing process of the cement is difficult because of their complexity and has not resulted in sufficiently precise mathematical models. In this paper, based on a statistical model of the process and using the knowledge of human experts, was designed a fuzzy system for automatic control of clinkering process.
W.A. Stolk (Wilma); S.J. de Vlas (Sake); J.D.F. Habbema (Dik)
2006-01-01
textabstractMathematical simulation models for transmission and control of lymphatic filariasis are useful tools for studying the prospects of lymphatic filariasis elimination. Two simulation models are currently being used. The first, EPIFIL, is a population-based, deterministic model that simulate
Mathematical Modelling and the Learning Trajectory: Tools to Support the Teaching of Linear Algebra
Cárcamo Bahamonde, Andrea Dorila; Fortuny Aymemí, Josep Maria; Gómez i Urgellés, Joan Vicenç
2017-01-01
In this article we present a didactic proposal for teaching linear algebra based on two compatible theoretical models: emergent models and mathematical modelling. This proposal begins with a problematic situation related to the creation and use of secure passwords, which leads students toward the construction of the concepts of spanning set and…
A mathematical human body model for frontal and rearward seated automotive impact loading
Happee, R.; Hoofman, R.; Kroonenberg, A.J. van den; Morsink, P.L.J.; Wismans, J.S.H.M.
1998-01-01
Mathematical modelling is widely used for crash-safety research and design. However, most occupant models used in crash simulations are based on crash dummies and thereby inherit their apparent limitations. Several models simulating parts of the real human body have been published, but only few desc
Aufa, Mahrani; Saragih, Sahat; Minarni, Ani
2016-01-01
The purposes of this study were:1) Developed problem-based on learning tools in the cultural context of Aceh (PBM-BKBA) who meet the criteria are valid, practical and effective; 2) Described the improvement of communication capabilities mathematics and social skills of students using the PBM-BKBA developed; and 3) Described the process of student…
Andasari, Vivi; Gerisch, Alf; Lolas, Georgios; South, Andrew P; Chaplain, Mark A J
2011-07-01
The ability of cancer cells to break out of tissue compartments and invade locally gives solid tumours a defining deadly characteristic. One of the first steps of invasion is the remodelling of the surrounding tissue or extracellular matrix (ECM) and a major part of this process is the over-expression of proteolytic enzymes, such as the urokinase-type plasminogen activator (uPA) and matrix metalloproteinases (MMPs), by the cancer cells to break down ECM proteins. Degradation of the matrix enables the cancer cells to migrate through the tissue and subsequently to spread to secondary sites in the body, a process known as metastasis. In this paper we undertake an analysis of a mathematical model of cancer cell invasion of tissue, or ECM, which focuses on the role of the urokinase plasminogen activation system. The model consists of a system of five reaction-diffusion-taxis partial differential equations describing the interactions between cancer cells, uPA, uPA inhibitors, plasmin and the host tissue. Cancer cells react chemotactically and haptotactically to the spatio-temporal effects of the uPA system. The results obtained from computational simulations carried out on the model equations produce dynamic heterogeneous spatio-temporal solutions and using linear stability analysis we show that this is caused by a taxis-driven instability of a spatially homogeneous steady-state. Finally we consider the biological implications of the model results, draw parallels with clinical samples and laboratory based models of cancer cell invasion using three-dimensional invasion assay, and go on to discuss future development of the model.
Liao, Wenlin; Dai, Yifan; Xie, Xuhui; Zhou, Lin
2014-07-01
Ion beam figuring (IBF) is established for the final precision figuring of high-performance optical components, where the figuring accuracy is guaranteed by the stability of the removal function and the solution accuracy of the dwell time. In this deterministic method, the figuring process can be represented by a two-dimensional (2D) convolution operation of a constant removal function and the dwell time. However, we have found that the current 2D convolution operation cannot factually describe the IBF process of curved surfaces, which neglects the influences of the projection distortion and the workpiece geometry on the removal function. Consequently, the current 2D convolution algorithm would influence the solution accuracy for the dwell time and reduce the convergence of the figuring process. In this part, based on the material removal characteristics of IBF, a mathematical model of the removal function is developed theoretically and verified experimentally. Research results show that the removal function during IBF of a curved surface is actually a dynamic function in the 2D convolution algorithm. The mathematical modeling of the dynamic removal function provides theoretical foundations for our proposed new algorithm in the next part, and final verification experiments indicate that this algorithm can effectively improve the accuracy of the dwell time solution for the IBF of curved surfaces.
Mathematical Modeling of the Induced Mutation Process in Bacterial Cells
Belov, Oleg V.; Krasavin, Evgeny A.; Parkhomenko, Alexander Yu.
2010-01-01
A mathematical model of the ultraviolet (UV) irradiation-induced mutation process in bacterial cells Escherichia coli is developed. Using mathematical approaches, the whole chain of events is tracked from a cell exposure to the damaging factor to mutation formation in the DNA chain. An account of the key special features of the regulation of this genetic network allows predicting the effects induced by the cell exposure to certain UV energy fluence.
BUILDING MATHEMATICAL MODELS IN DYNAMIC PROGRAMMING
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LIANA RODICA PATER
2012-05-01
Full Text Available In short, we can say that dynamic programming is a method of optimization of systems, using their mathematical representation in phases or sequences or as we say, periods. Such systems are common in economic studies at the implementation of programs on the most advanced techniques, such as for example that involving cosmic navigation. Another concept that is involved in the study of dynamic programs is the economic horizon (number of periods or phases that a dynamic program needs. This concept often leads to the examination of the convergence of certain variables on infinite horizon. In many cases from the real economy by introducing updating, dynamic programs can be made convergent.
Wada, B. K.; Kuo, C-P.; Glaser, R. J.
1986-01-01
For the structural dynamic analysis of large space structures, the technology in structural synthesis and the development of structural analysis software have increased the capability to predict the dynamic characteristics of the structural system. The various subsystems which comprise the system are represented by various displacement functions; the displacement functions are then combined to represent the total structure. Experience has indicated that even when subsystem mathematical models are verified by test, the mathematical representations of the total system are often in error because the mathematical model of the structural elements which are significant when loads are applied at the interconnection points are not adequately verified by test. A multiple test concept, based upon the Multiple Boundary Condition Test (MBCT), is presented which will increase the accuracy of the system mathematical model by improving the subsystem test and test/analysis correlation procedure.
Investigating and developing engineering students' mathematical modelling and problem-solving skills
Wedelin, Dag; Adawi, Tom; Jahan, Tabassum; Andersson, Sven
2015-09-01
How do engineering students approach mathematical modelling problems and how can they learn to deal with such problems? In the context of a course in mathematical modelling and problem solving, and using a qualitative case study approach, we found that the students had little prior experience of mathematical modelling. They were also inexperienced problem solvers, unaware of the importance of understanding the problem and exploring alternatives, and impeded by inappropriate beliefs, attitudes and expectations. Important impacts of the course belong to the metacognitive domain. The nature of the problems, the supervision and the follow-up lectures were emphasised as contributing to the impacts of the course, where students show major development. We discuss these empirical results in relation to a framework for mathematical thinking and the notion of cognitive apprenticeship. Based on the results, we argue that this kind of teaching should be considered in the education of all engineers.
Hu, Tingzhang; Zeng, Hua; Chen, Zaigang; Huang, Xiaoyun; Yang, Yongwei; Wang, Guixue
2012-09-01
Using uniform random design optimization and the mathematical model equation we optimized the regeneration tissue culture system of the chilli pepper. An efficient and detailed plant reproducible protocol in vitro has been established using different explants and induction media for three chilli pepper cultivars. The result displayed that the seedlings at the curved hypocotyl stage were the best choice to prepare for explants, the genotype of explants affected shoot buds induction frequency and number of shoot buds per explant, and the cotyledon explant was more responsive than hypocotyl explant. The optimal media for maximum shoot initiation and regeneration and the optimal elongation medium were obtained. For Capsicum annuum var. annuum (cv. Xinsu), Capsicum annuum var. annuum (cv. Neimengchifeng) and Capsicum frutescens (cv. Xingfu), the induction rates were 99.17%, 97.50 and 96.11%, respectively; the elongation rates of shoot buds were 86.67%, 85.19% and 82.96%, respectively. The MS medium with 0.57 μM IAA and 0.69 μM NAA is the best choice for root induction. The frequency of their root emergence was 95.00-98.33%. Regenerated chilli peppers were successfully acclimatized and cultivated with 100% survival. This work will help to improve multiplication process and the genotype of chilli pepper, and may have commercial impact.
A mathematical model of cancer cells with phenotypic plasticity
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Da Zhou
2015-12-01
Full Text Available Purpose: The phenotypic plasticity of cancer cells is recently becoming a cutting-edge research area in cancer, which challenges the cellular hierarchy proposed by the conventional cancer stem cell theory. In this study, we establish a mathematical model for describing the phenotypic plasticity of cancer cells, based on which we try to find some salient features that can characterize the dynamic behavior of the phenotypic plasticity especially in comparison to the hierarchical model of cancer cells. Methods: We model cancer as population dynamics composed of different phenotypes of cancer cells. In this model, not only can cancer cells divide (symmetrically and asymmetrically and die, but they can also convert into other cellular phenotypes. According to the Law of Mass Action, the cellular processes can be captured by a system of ordinary differential equations (ODEs. On one hand, we can analyze the long-term stability of the model by applying qualitative method of ODEs. On the other hand, we are also concerned about the short-term behavior of the model by studying its transient dynamics. Meanwhile, we validate our model to the cell-state dynamics in published experimental data.Results: Our results show that the phenotypic plasticity plays important roles in both stabilizing the distribution of different phenotypic mixture and maintaining the cancer stem cells proportion. In particular, the phenotypic plasticity model shows decided advantages over the hierarchical model in predicting the phenotypic equilibrium and cancer stem cells’ overshoot reported in previous biological experiments in cancer cell lines.Conclusion: Since the validity of the phenotypic plasticity paradigm and the conventional cancer stem cell theory is still debated in experimental biology, it is worthy of theoretically searching for good indicators to distinguish the two models through quantitative methods. According to our study, the phenotypic equilibrium and overshoot
Mathematical Modeling of the Vacuum Circulation Refining Processof Molten Steel
Institute of Scientific and Technical Information of China (English)
魏季和
2003-01-01
The available studies in the literature on mathematical modeling of the vacuum circulation (RH) refining process of molten steel have briefly been reviewed. The latest advances obtained by the author with his research group have been Summarized. On the basis of the mass and momentum balances in the system, a new mathematical model for decarburization and degassing during the RH and RH-KTB refining processes of molten steel was proposed and developed. The refining roles of the three reaction sites, i.e. the up-snorkel zone, the droplet group and steel bath in the vacuum vessel, were considered in the model. It was assumed that the mass transfer of reactive components in the molten steel is the rate control step of the refining reactions. And the friction losses and drags of flows in the snorkels and vacuum vessel were all counted. The model was applied to the refining of molten steel in a multifunction RH degasser of 90 t capacity. The decarburization and degassing processes in the degasser under the RH and RH-KTB operating condi-tions were modeled and analyzed using this model. Besides, proceeded from the two-resistance mass transfer theory and the mass bal-ance of sulphur in the system, a kinetic model for the desulphurization by powder injection and blowing in the RH refining of molten steel was developed. Modeling and predictions of the process of injecting and blowing the lime based powder flux under assumed oper-ating modes with the different initial contents of sulphur and amounts of powder injected and blown in a RH degasser of 300 t capacity were carried out using the model. It was demonstrated that for the RH and RH-KTB refining processes, and the desulphurization by powder injection and blowing in the RH refining, the results predicted by the models were all in good agreement respectively with data from industrial experiments and practice. These models may be expected to offer some useful information and a reliable basis for de-termining and optimizing
A Mathematical Model of a Direct Propane Fuel Cell
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Hamidreza Khakdaman
2015-01-01
Full Text Available A rigorous mathematical model for direct propane fuel cells (DPFCs was developed. Compared to previous models, it provides better values for the current density and the propane concentration at the exit from the anode. This is the first DPFC model to correctly account for proton transport based on the combination of the chemical potential gradient and the electrical potential gradient. The force per unit charge from the chemical potential gradient (concentration gradient that pushes protons from the anode to the cathode is greater than that from the electrical potential gradient that pushes them in the opposite direction. By including the chemical potential gradient, we learn that the proton concentration gradient is really much different than that predicted using the previous models that neglected the chemical potential gradient. Also inclusion of the chemical potential gradient made this model the first one having an overpotential gradient (calculated from the electrical potential gradient with the correct slope. That is important because the overpotential is exponentially related to the reaction rate (current density. The model described here provides a relationship between the conditions inside the fuel cell (proton concentration, overpotential and its performance as measured externally by current density and propane concentration.
Mathematical modeling of HIV-like particle assembly in vitro.
Liu, Yuewu; Zou, Xiufen
2017-02-22
In vitro, the recombinant HIV-1 Gag protein can generate spherical particles with a diameter of 25-30 nm in a fully defined system. It has approximately 80 building blocks, and its intermediates for assembly are abundant in geometry. Accordingly, there are a large number of nonlinear equations in the classical model. Therefore, it is difficult to compute values of geometry parameters for intermediates and make the mathematical analysis using the model. In this work, we develop a new model of HIV-like particle assembly in vitro by using six-fold symmetry of HIV-like particle assembly to decrease the number of geometry parameters. This method will greatly reduce computational costs and facilitate the application of the model. Then, we prove the existence and uniqueness of the positive equilibrium solution for this model with 79 nonlinear equations. Based on this model, we derive the interesting result that concentrations of all intermediates at equilibrium are independent of three important parameters, including two microscopic on-rate constants and the size of nucleating structure. Before equilibrium, these three parameters influence the concentration variation rates of all intermediates. We also analyze the relationship between the initial concentration of building blocks and concentrations of all intermediates. Furthermore, the bounds of concentrations of free building blocks and HIV-like particles are estimated. These results will be helpful to guide HIV-like particle assembly experiments and improve our understanding of the assembly dynamics of HIV-like particles in vitro.
An evaluation of mathematical models for predicting skin permeability.
Lian, Guoping; Chen, Longjian; Han, Lujia
2008-01-01
A number of mathematical models have been proposed for predicting skin permeability, mostly empirical and very few are deterministic. Early empirical models use simple lipophilicity parameters. The recent trend is to use more complicated molecular structure descriptors. There has been much debate on which models best predict skin permeability. This article evaluates various mathematical models using a comprehensive experimental dataset of skin permeability for 124 chemical compounds compiled from various sources. Of the seven models compared, the deterministic model of Mitragotri gives the best prediction. The simple quantitative structure permeability relationships (QSPR) model of Potts and Guy gives the second best prediction. The two models have many features in common. Both assume the lipid matrix as the pathway of transdermal permeation. Both use octanol-water partition coefficient and molecular size. Even the mathematical formulae are similar. All other empirical QSPR models that use more complicated molecular structure descriptors fail to provide satisfactory prediction. The molecular structure descriptors in the more complicated QSPR models are empirically related to skin permeation. The mechanism on how these descriptors affect transdermal permeation is not clear. Mathematically it is an ill-defined approach to use many colinearly related parameters rather than fewer independent parameters in multi-linear regression.
Mathematical models and numerical simulation in electromagnetism
Bermúdez, Alfredo; Salgado, Pilar
2014-01-01
The book represents a basic support for a master course in electromagnetism oriented to numerical simulation. The main goal of the book is that the reader knows the boundary-value problems of partial differential equations that should be solved in order to perform computer simulation of electromagnetic processes. Moreover it includes a part devoted to electric circuit theory based on ordinary differential equations. The book is mainly oriented to electric engineering applications, going from the general to the specific, namely, from the full Maxwell’s equations to the particular cases of electrostatics, direct current, magnetostatics and eddy currents models. Apart from standard exercises related to analytical calculus, the book includes some others oriented to real-life applications solved with MaxFEM free simulation software.
A Mathematical Model of Democratic Elections
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Mato Nagel
2010-09-01
Full Text Available Democratic election is the preferred method for determining political administrators nowadays. The intention is to find the best possible leader in order to improve the group's competitiveness and success. Though preferred, democratic election is far from being optimal in this respect, and is increasingly becoming the target for fraud. A model was developed to scientifically analyze the present electoral system's insufficiency. It is based on fauceir assumptions. Its calculations enable principles to be developed that optimize the election process, while also revealing the limits of elections in societies growing ever more complex, so that in the end elections have to be replaced by processes similar to what has proved optimal throughout naturally occurring evolution-natural selection.
Methods of mathematical modelling continuous systems and differential equations
Witelski, Thomas
2015-01-01
This book presents mathematical modelling and the integrated process of formulating sets of equations to describe real-world problems. It describes methods for obtaining solutions of challenging differential equations stemming from problems in areas such as chemical reactions, population dynamics, mechanical systems, and fluid mechanics. Chapters 1 to 4 cover essential topics in ordinary differential equations, transport equations and the calculus of variations that are important for formulating models. Chapters 5 to 11 then develop more advanced techniques including similarity solutions, matched asymptotic expansions, multiple scale analysis, long-wave models, and fast/slow dynamical systems. Methods of Mathematical Modelling will be useful for advanced undergraduate or beginning graduate students in applied mathematics, engineering and other applied sciences.
Mathematical model of layered metallurgical furnaces and units
Shvydkiy, V. S.; Spirin, N. A.; Lavrov, V. V.
2016-09-01
The basic approaches to mathematical modeling of the layered steel furnaces and units are considered. It is noted that the particular importance have the knowledge about the mechanisms and physical nature of processes of the charge column movement and the gas flow in the moving layer, as well as regularities of development of heat- and mass-transfer in them. The statement and mathematical description of the problem solution targeting the potential gas flow in the layered unit of an arbitrary profile are presented. On the basis of the proposed mathematical model the software implementation of information-modeling system of BF gas dynamics is carried out. The results of the computer modeling of BF non-isothermal gas dynamics with regard to the cohesion zone, gas dynamics of the combustion zone and calculation of hot-blast stoves are provided
Mathematical and Computational Modeling of Polymer Exchange Membrane Fuel Cells
Ulusoy, Sehribani
In this thesis a comprehensive review of fuel cell modeling has been given and based on the review, a general mathematical fuel cell model has been developed in order to understand the physical phenomena governing the fuel cell behavior and in order to contribute to the efforts investigating the optimum performance at different operating conditions as well as with different physical parameters. The steady state, isothermal model presented here accounts for the combined effects of mass and species transfer, momentum conservation, electrical current distribution through the gas channels, the electrodes and the membrane, and the electrochemical kinetics of the reactions in the anode and cathode catalyst layers. One of the important features of the model is that it proposes a simpler modified pseudo-homogeneous/agglomerate catalyst layer model which takes the advantage of the simplicity of pseudo-homogenous modeling while taking into account the effects of the agglomerates in the catalyst layer by using experimental geometric parameters published. The computation of the general mathematical model can be accomplished in 3D, 2D and 1D with the proper assumptions. Mainly, there are two computational domains considered in this thesis. The first modeling domain is a 2D Membrane Electrode Assembly (MEA) model including the modified agglomerate/pseudo-homogeneous catalyst layer modeling with consistent treatment of water transport in the MEA while the second domain presents a 3D model with different flow filed designs: straight, stepped and tapered. COMSOL Multiphysics along with Batteries and Fuel Cell Module have been used for 2D & 3D model computations while ANSYS FLUENT PEMFC Module has been used for only 3D two-phase computation. Both models have been validated with experimental data. With 2D MEA model, the effects of temperature and water content of the membrane as well as the equivalent weight of the membrane on the performance have been addressed. 3D COMSOL simulation
Stein, Sherman K
2010-01-01
Anyone can appreciate the beauty, depth, and vitality of mathematics with the help of this highly readable text, specially developed from a college course designed to appeal to students in a variety of fields. Readers with little mathematical background are exposed to a broad range of subjects chosen from number theory, topology, set theory, geometry, algebra, and analysis. Starting with a survey of questions on weight, the text discusses the primes, the fundamental theorem of arithmetic, rationals and irrationals, tiling, tiling and electricity, probability, infinite sets, and many other topi
Predictive control applied to an evaporator mathematical model
Directory of Open Access Journals (Sweden)
Daniel Alonso Giraldo Giraldo
2010-07-01
Full Text Available This paper outlines designing a predictive control model (PCM applied to a mathematical model of a falling film evaporator with mechanical steam compression like those used in the dairy industry. The controller was designed using the Connoisseur software package and data gathered from the simulation of a non-linear mathematical model. A control law was obtained from minimising a cost function sublect to dynamic system constraints, using a quadratic programme (QP algorithm. A linear programming (LP algorithm was used for finding a sub-optimal operation point for the process in stationary state.
Analysis of mathematical model for micromechanical vibratory wheel gyroscope
Institute of Scientific and Technical Information of China (English)
LUO Yue-sheng; FAN Chong-jin; TAN Zhen-fan
2003-01-01
By the sketch of structure of MVWG,the working laws of this kind of gyroscope were explained.To the aid of Euler′s Dynamics Equation,a mathematical model of the gyroscope was constructed,and then by the basic working laws of MVWG the model was simplified.Under the conditions of the three axial direction rotations and general rotation,the mathematical model was resolved.And finally by the solutions, the working laws of the gyroscope, the working disparity among all sorts of gyrations and the influences from the gyrations in the axial directions were analysed.
Solutions manual to accompany finite mathematics models and applications
Morris, Carla C
2015-01-01
A solutions manual to accompany Finite Mathematics: Models and Applications In order to emphasize the main concepts of each chapter, Finite Mathematics: Models and Applications features plentiful pedagogical elements throughout such as special exercises, end notes, hints, select solutions, biographies of key mathematicians, boxed key principles, a glossary of important terms and topics, and an overview of use of technology. The book encourages the modeling of linear programs and their solutions and uses common computer software programs such as LINDO. In addition to extensive chapters on pr
Mathematical Models of the Sinusoidal Screen Family
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Tajana Koren
2011-06-01
Full Text Available In this paper we will define a family of sinusoidal screening elements and explore the possibilities of their application in graphic arts, securities printing and design solutions in photography and typography editing. For this purpose mathematical expressions of sinusoidal families were converted into a Postscript language. The introduction of a random variable results in a countless number of various mutations which cannot be repeated without knowing the programming code itself. The use of the family of screens in protection of securities is thus of great importance. Other possible application of modulated sinusoidal screens is related to the large format color printing. This paper will test the application of sinusoidal screens in vector graphics, pixel graphics and typography. The development of parameters in the sinusoidal screen element algorithms gives new forms defined within screening cells with strict requirements of coverage implementation. Individual solutions include stochastic algorithms, as well as the autonomy of screening forms in regard to multicolor printing channels.
MATHEMATICAL MODELING FOR ERYTHROMYCIN POTENCY DETERMINATION OF MASTIKER
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Victorita Burghelea
2016-12-01
Full Text Available Mastiker E is an antibacterial suspension for intramammary infusion in cattle mastitis. The active drug is erythromycin, a macrolide antibiotic. The main characteristic of commercial product is erythromycin potency. The potency of erythromycin is estimated by comparing the inhibition of growth of sensitive micro-organisms produced by known concentrations of the antibiotic to be examined and a reference substance. The validation study aims to demonstrate the determination of the potency of erythromycin, it is an appropriate analytical method, reproducible and meets the quality requirements of Mastiker product. The paper establishes the performance characteristics of the method considered and identify the factors that influence these characteristics. The diameters of inhibition zones, directly proportional to the logarithm of the concentration of the antibiotic used for the assay, measured and calculated using statistical methods (Combistats Soft. The assay is designed in such a way that the mathematical model on which the potency equation is based can be proved to be valid. A parallel-line model is chosen. The two log dose response lines of the preparation under examination and the standard preparation are parallel; they are rectilinear over the range of doses used in the calculation. These conditions are verified by validity tests for a given probability (P = 0.05. The test is not valid unless the confidence limits (P = 0.95 are not less than 50% and not more than 200% of the estimated potency. The estimated potency is not less than 95% and not more than 105% of the stated potency. The stated potency is not less than 50.000 IU/g. The validation procedure includes details on protocol working to determine the potency of erythromycin, validation criteria, experimental results, mathematical modeling for determining the potency, inter laboratory comparisons.
MATHEMATIC MODEL FOR SITY BUS SCHEDULING IN YOGYAKARTA
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Sahid Sahid
2016-05-01
Full Text Available Various methods can be used to construct a mathematical model of the transportation problems. One model that can be used is a linear model. Several studies have used a linear model to get the schedule and the optimal route of bus trips. This research will build a mathematical model of a city bus transportation problems in DIY using linear models. Linear model is built to get the condition density city bus passengers on shifts respectively that morning, noon, and evening. After finding a suitable model, applied to the bus passengers data in Yogyakarta. From these results it can be seen the optimum conditions in terms of density, because the condition of the city bus at this time that quiet enthusiasts. Besides, the optimum density at each shift in the morning is 11 passengers, 10 passengers during the day, and evening 9 passengers. Keywords: transportation problems, the linear model, the optimal route, density
A mathematical model of tumor–immune interactions
Robertson-Tessi, Mark
2012-02-01
A mathematical model of the interactions between a growing tumor and the immune system is presented. The equations and parameters of the model are based on experimental and clinical results from published studies. The model includes the primary cell populations involved in effector T-cell mediated tumor killing: regulatory T cells, helper T cells, and dendritic cells. A key feature is the inclusion of multiple mechanisms of immunosuppression through the main cytokines and growth factors mediating the interactions between the cell populations. Decreased access of effector cells to the tumor interior with increasing tumor size is accounted for. The model is applied to tumors with different growth rates and antigenicities to gauge the relative importance of various immunosuppressive mechanisms. The most important factors leading to tumor escape are TGF-Β-induced immunosuppression, conversion of helper T cells into regulatory T cells, and the limitation of immune cell access to the full tumor at large tumor sizes. The results suggest that for a given tumor growth rate, there is an optimal antigenicity maximizing the response of the immune system. Further increases in antigenicity result in increased immunosuppression, and therefore a decrease in tumor killing rate. This result may have implications for immunotherapies which modulate the effective antigenicity. Simulation of dendritic cell therapy with the model suggests that for some tumors, there is an optimal dose of transfused dendritic cells. © 2011 Elsevier Ltd.
Analysis of rear end impact using mathematical human modelling
Happee, R.; Meijer, R.; Horst, M.J. van der; Ono, K.; Yamazaki, K.
2000-01-01
At TNO an omni-directional mathematical human body model has been developed. Until now this human model has been validated for frontal and lateral loading using response data of volunteer and post mortem human subject (PMHS) sled tests. For rearward loading it has been validated for high speed impac
Precipitation of metal sulphides using gaseous hydrogen sulphide : mathematical modelling
Tarazi, Mousa Al-; Heesink, A. Bert M.; Versteeg, Geert F.
2004-01-01
A mathematical model has been developed that describes the precipitation of metal sulphides in an aqueous solution containing two different heavy metal ions. The solution is assumed to consist of a well-mixed bulk and a boundary layer that is contacted with hydrogen sulphide gas. The model makes use
Metaphors and Models in Translation between College and Workplace Mathematics
Williams, Julian; Wake, Geoff
2007-01-01
We report a study of repairs in communication between workers and visiting outsiders (students, researchers or teachers). We show how cultural models such as metaphors and mathematical models facilitated explanations and repair work in inquiry and pedagogical dialogues. We extend previous theorisations of metaphor by Black; Lakoff and Johnson;…
Applicability of mathematical modeling to problems of environmental physiology
White, Ronald J.; Lujan, Barbara F.; Leonard, Joel I.; Srinivasan, R. Srini
1988-01-01
The paper traces the evolution of mathematical modeling and systems analysis from terrestrial research to research related to space biomedicine and back again to terrestrial research. Topics covered include: power spectral analysis of physiological signals; pattern recognition models for detection of disease processes; and, computer-aided diagnosis programs used in conjunction with a special on-line biomedical computer library.
Invention software support by integrating function and mathematical modeling
Chechurin, L.S.; Wits, W.W.; Bakker, H.M.
2015-01-01
New idea generation is imperative for successful product innovation and technology development. This paper presents the development of a novel type of invention support software. The support tool integrates both function modeling and mathematical modeling, thereby enabling quantitative analyses on a
The Singing Wineglass: An Exercise in Mathematical Modelling
Voges, E. L.; Joubert, S. V.
2008-01-01
Lecturers in mathematical modelling courses are always on the lookout for new examples to illustrate the modelling process. A physical phenomenon, documented as early as the nineteenth century, was recalled: when a wineglass "sings", waves are visible on the surface of the wine. These surface waves are used as an exercise in mathematical…