WorldWideScience

Sample records for ausleseprototyp mit gems

  1. Graphics gems

    CERN Document Server

    Glassner, Andrew S

    1993-01-01

    ""The GRAPHICS GEMS Series"" was started in 1990 by Andrew Glassner. The vision and purpose of the Series was - and still is - to provide tips, techniques, and algorithms for graphics programmers. All of the gems are written by programmers who work in the field and are motivated by a common desire to share interesting ideas and tools with their colleagues. Each volume provides a new set of innovative solutions to a variety of programming problems.

  2. Graphics gems

    CERN Document Server

    Heckbert, Paul S

    1994-01-01

    Graphics Gems IV contains practical techniques for 2D and 3D modeling, animation, rendering, and image processing. The book presents articles on polygons and polyhedral; a mix of formulas, optimized algorithms, and tutorial information on the geometry of 2D, 3D, and n-D space; transformations; and parametric curves and surfaces. The text also includes articles on ray tracing; shading 3D models; and frame buffer techniques. Articles on image processing; algorithms for graphical layout; basic interpolation methods; and subroutine libraries for vector and matrix algebra are also demonstrated. Com

  3. GPU Computing Gems Emerald Edition

    CERN Document Server

    Hwu, Wen-mei W

    2011-01-01

    ".the perfect companion to Programming Massively Parallel Processors by Hwu & Kirk." -Nicolas Pinto, Research Scientist at Harvard & MIT, NVIDIA Fellow 2009-2010 Graphics processing units (GPUs) can do much more than render graphics. Scientists and researchers increasingly look to GPUs to improve the efficiency and performance of computationally-intensive experiments across a range of disciplines. GPU Computing Gems: Emerald Edition brings their techniques to you, showcasing GPU-based solutions including: Black hole simulations with CUDA GPU-accelerated computation and interactive display of

  4. Gas amplification properties of GEM foils; Gasverstaerkungseigenschaften von GEM-Folien

    Energy Technology Data Exchange (ETDEWEB)

    Beck, Jeannine

    2009-01-15

    procedure were developed and a laser-measurement arrangement for the measurement of GEM surface profiles designed and tested. The Planeness of framed GEM foils was determined, whereby height differences up to 1 mm resulted. [German] Im Rahmen des Detektorkonzeptes International Linear Detector fuer das kuenftige Beschleunigerprojekt International Linear Collider, an dem Elektronen und Positronen bei Schwerpunktsenergien von 500 GeV zur Kollision gebracht werden, soll eine Zeit-Projektions-Kammer als zentrale Spurkammer eingesetzt werden. Mit der Verwendung einer derartigen Kammer als Spurdetektor ist eine dreidimensionale Rekonstruktion der Spurpunkte moeglich. Durchfliegt ein Teilchen das Gasvolumen innerhalb der Kammer, ionisiert es einzelne Gasatome und die entstandenen Elektronen bewegen sich nach der Verstaerkung in der GEM-Anordnung (engl. Gas Electron Multiplier) zur Anode, so dass eine zweidimensionale Projektion der Teilchenspur moeglich ist. Die dritte Dimension wird aus der Driftzeit der Elektronen errechnet. Die Vorteile dieses Auslesesystems bestehen darin, dass eine bessere Ortsaufloesung als mit einer Vieldraht-Proportional-Kammer erreicht wird und die rueckdriftenden Ionen stark unterdrueckt werden koennen. Ziel dieser Arbeit sind Untersuchungen fuer ein GEM-Modul, das in einem grossen TPCPrototypen genutzt werden soll. Hinsichtlich verschiedener Anforderungen gilt es unterschiedliche GEMs zu vergleichen, um eine optimale Auswahl treffen zu koennen. In einem am DESY vorhandenen kleinen Prototypen wurden Messungen zur Erfassung von GEM-beschreibenden Parametern durchgefuehrt. Die Inbetriebnahme der Test-TPC war Bestandteil dieser Arbeit. Es wurden Spuren durch eine radioaktive Quelle erzeugt, mit deren Hilfe die Gasverstaerkung bestimmt wurde. Mit dem Messaufbau wurden verschiedenartige Gasverstaerkerfolien hinsichtlich ihrer Verstaerkungseigenschaften und ihres Energieaufloesungsvermoegens verglichen und systematisch studiert. Es wurden fuenf

  5. GEM Detector Electric Field Simulation

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    GEM (Gas Electron Multiplier) detectors have been widely employed in the experimental field of high energy physics and nuclear physics. As a successor to drift chambers, GEMs are much easier to fabricate and have a much higher spatial resolution

  6. GEM Technical Design Report

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-31

    The GEM collaboration was formed in June 1991 to develop a major detector for the SSC. The primary physics objectives of GEM are those central to the motivation for the SSC, to study high p{sub T} physics - exemplified by the search for Higgs bosons - and to search for new physics beyond the standard model. The authors present in this Technical Design Report (TDR) a detector with broad capabilities for the discovery and subsequent study of electroweak symmetry breaking, the origin of mass and flavor, and other physics requiring precise measurements of gammas, electrons, and muons - hence the name, GEM. In addition, as a design goal, they have taken care to provide the robustness needed to do the physics that requires high luminosity. Finally, good coverage and hermeticity allow the detection of missing transverse energy, E{sub T}. The GEM design emphasizes clean identification and high resolution measurement of the primary physics signatures for high p{sub T} physics. The approach is to make precise energy measurements that maximize the sensitivity to rare narrow resonances, to detect the elementary interaction products (quarks, leptons, and photons), and to build in the features required to reduce backgrounds.

  7. Graphics gems V (Macintosh version)

    CERN Document Server

    Paeth, Alan W

    1995-01-01

    Graphics Gems V is the newest volume in The Graphics Gems Series. It is intended to provide the graphics community with a set of practical tools for implementing new ideas and techniques, and to offer working solutions to real programming problems. These tools are written by a wide variety of graphics programmers from industry, academia, and research. The books in the series have become essential, time-saving tools for many programmers.Latest collection of graphics tips in The Graphics Gems Series written by the leading programmers in the field.Contains over 50 new gems displaying some of t

  8. Graphics Gems III IBM version

    CERN Document Server

    Kirk, David

    1994-01-01

    This sequel to Graphics Gems (Academic Press, 1990), and Graphics Gems II (Academic Press, 1991) is a practical collection of computer graphics programming tools and techniques. Graphics Gems III contains a larger percentage of gems related to modeling and rendering, particularly lighting and shading. This new edition also covers image processing, numerical and programming techniques, modeling and transformations, 2D and 3D geometry and algorithms,ray tracing and radiosity, rendering, and more clever new tools and tricks for graphics programming. Volume III also includes a

  9. Graphics gems II

    CERN Document Server

    Arvo, James

    1991-01-01

    Graphics Gems II is a collection of articles shared by a diverse group of people that reflect ideas and approaches in graphics programming which can benefit other computer graphics programmers.This volume presents techniques for doing well-known graphics operations faster or easier. The book contains chapters devoted to topics on two-dimensional and three-dimensional geometry and algorithms, image processing, frame buffer techniques, and ray tracing techniques. The radiosity approach, matrix techniques, and numerical and programming techniques are likewise discussed.Graphics artists and comput

  10. Characterisations of GEM detector prototype

    Energy Technology Data Exchange (ETDEWEB)

    Patra, Rajendra Nath [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700064, West Bengal (India); Nanda, Amit [School of Physical Sciences, National Institute of Science Education and Research, Jatni 752050 (India); Rudra, Sharmili [Department of Applied Physics, CU, 92, APC Road, Kolkata 700009, West Bengal (India); Bhattacharya, P.; Sahoo, Sumanya Sekhar [School of Physical Sciences, National Institute of Science Education and Research, Jatni 752050 (India); Biswas, S., E-mail: saikat.ino@gmail.com [School of Physical Sciences, National Institute of Science Education and Research, Jatni 752050 (India); Mohanty, B. [School of Physical Sciences, National Institute of Science Education and Research, Jatni 752050 (India); Nayak, T.K. [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700064, West Bengal (India); Sahu, P.K.; Sahu, S. [Institute of Physics, Sachivalaya Marg, P.O.: Sainik School, Bhubaneswar 751005, Odisha (India)

    2016-07-11

    At NISER-IoP detector laboratory an initiative is taken to build and test Gas Electron Multiplier (GEM) detectors for ALICE experiment. The optimisation of the gas flow rate and the long-term stability test of the GEM detector are performed. The method and test results are presented.

  11. Characterizations of GEM detector prototype

    CERN Document Server

    Patra, Rajendra Nath; Rudra, Sharmili; Bhattacharya, P.; Sahoo, Sumanya Sekhar; Biswas, S.; Mohanty, B.; Nayak, T.K.; Sahu, P.K.; Sahu, S.

    2016-01-01

    At NISER-IoP detector laboratory an initiative is taken to build and test Gas Electron Multiplier (GEM) detectors for ALICE experiment. The optimisation of the gas flow rate and the long-term stability test of the GEM detector are performed. The method and test results are presented.

  12. Bedeutung des Gemüsebaus für die Landwirtschaft von Wielkopolska

    Directory of Open Access Journals (Sweden)

    Karolina Jąder

    2009-01-01

    Full Text Available In dem Artikel wurde die Bedeutung des Gemüsebaus für die Landwirtschaft der Region Wielkopolska präsentiert. Diese Bedeutung wurde mit Hilfe von einigen Kriterien bestimmt. Es wurden dargestellt: der Anteil der Gemüsefläche an der gesamten landwirtschaftlichen Nutzfläche von Wielkopolska und der Gemüseanteil in der Brutto- und Warenproduktion der regionalen Landwirtschaft und der Pflanzenabteilung. Der Anteil der Freilandgemüsefläche an der landwirtschaftlichen Nutzfläche lag bei 1,36 bis 1,56 Prozent und der Anteil der Gewächshausgemüsefläche an der landwirtschaftlichen Nutzfläche oszillierte von 0,017 bis 0,050 Prozent. Die Gemüseproduktion lag bei 4,67 Prozent der Bruttoproduktion der Landwirtschaft von Wielkopolska, und der Anteil der Gemüseproduktion an der Warenproduktion der Landwirtschaft war in der Zeit auf einem ähnlichen Niveau – 4,66 Prozent. In der Pflanzenabteilung war die Bedeutung des Gemüsebaus noch größer als in der ganzen Landwirtschaft. Der Anteil von Gemüse an der Warenproduktion der Pflanzenabteilung lag durchschnittlich in den untersuchten Jahren bei 28, 54 Prozent.

  13. Technical Summaries of GEMS

    Institute of Scientific and Technical Information of China (English)

    孙家广; 辜凯宁; 等

    1989-01-01

    GEMS is a solid modelling system running on CAS workstation or 32 bits microcomputer with graphics terminal.Complex solid obj ects are built from transformation and set operations upon box,cylinder,cone,sphere,torus,sweeping object and other primitives.CEMS has explicit reatures.e.g.hierarchical modular structure, interactive user interfaceintuitional input,screen menu driven by data table,defining and instancing object in network construction,storage bases on CSG(Constructive Solid Geometry)and BReps(Boundary Representations).regularized set operations,transformation pipeline consistent with PHIGS graphics standard,various transformations,cutting object with two sections in arbitrary angle,patrolling to view the inside of an object,mapping patterns onto surfaces of an object etc.,Not only can it be used for the fields of spatial planning,architectural plan,CAD/CAM for machining,structure analysis,but it is also fundamental for developing the practical system of simulation,computer vision,robotics and so on.

  14. Untersuchung von Präferenzen für Obst und Gemüse von Grundschulkindern : Befragungen in fünf Schulklassen im Landkreis Rastatt

    OpenAIRE

    Bjarnason, Barbara

    2011-01-01

    Studien belegen, dass Kinder in Deutschland zu wenig Gemüse und Obst essen, so dass die ernährungsphysiologische und präventive Wertigkeit dieser Lebensmittelgruppe entsprechend der Verzehrsempfehlungen nicht erreicht werden. Diese Arbeit befasst sich mit der subjektiven Sichtweise von Grundschulkindern in Bezug auf Obst und Gemüse. Durch welche Eigenschaften und Einflüsse werden Vorlieben und Abneigungen bei der Obst- und Gemüseauswahl geprägt. Die Studie basiert auf einer Befragung üb...

  15. The PANDA GEM-based TPC prototype

    Energy Technology Data Exchange (ETDEWEB)

    Fabbietti, L., E-mail: laura.fabbietti@ph.tum.d [Excellence Cluster ' Universe' , Technische Universitaet Muenchen, Boltztmannstr. 2, Garching bei Muenchen 85748 (Germany); Angerer, H. [Physik Department E18, Technische Universitaet Muenchen, 85748 Muenchen (Germany); Arora, R. [Detektor Labor des GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Beck, R. [Helmholtz-Institut fuer Strahlen- und Kernphysik, 53115 Bonn (Germany); Berger, M. [Excellence Cluster ' Universe' , Technische Universitaet Muenchen, Boltztmannstr. 2, Garching bei Muenchen 85748 (Germany); Buehler, P.; Cargnelli, M. [Stefan-Meyer Institute fuer subatomare Physik, 1090 Vienna (Austria); Doerheim, S. [Physik Department E18, Technische Universitaet Muenchen, 85748 Muenchen (Germany); Hehner, J. [Detektor Labor des GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Herrmann, N. [FOPI Collaboration, GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Hoeppner, C. [Physik Department E18, Technische Universitaet Muenchen, 85748 Muenchen (Germany); Kaiser, D. [Helmholtz-Institut fuer Strahlen- und Kernphysik, 53115 Bonn (Germany); Ketzer, B. [Physik Department E18, Technische Universitaet Muenchen, 85748 Muenchen (Germany); Mladen, K. [FOPI Collaboration, GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Kleipa, V. [Detektor Labor des GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Konorov, I. [Physik Department E18, Technische Universitaet Muenchen, 85748 Muenchen (Germany); Kunkel, J. [Detektor Labor des GSI Helmholtzzentrum fuer Schwerionenforschung GmbH, 64291 Darmstadt (Germany); Lalik, R. [Excellence Cluster ' Universe' , Technische Universitaet Muenchen, Boltztmannstr. 2, Garching bei Muenchen 85748 (Germany); Lang, M. [Helmholtz-Institut fuer Strahlen- und Kernphysik, 53115 Bonn (Germany)

    2011-02-01

    We report on the development of a GEM-based TPC detector prototype for the PANDA experiment. The design and requirements of this device will be illustrated, with particular emphasis on the properties of the recently tested GEM-detector, the characterization of the read-out electronics and the development of the tracking software that allows to evaluate the GEM-TPC data.

  16. GEM - The Global Earthquake Model

    Science.gov (United States)

    Smolka, A.

    2009-04-01

    Over 500,000 people died in the last decade due to earthquakes and tsunamis, mostly in the developing world, where the risk is increasing due to rapid population growth. In many seismic regions, no hazard and risk models exist, and even where models do exist, they are intelligible only by experts, or available only for commercial purposes. The Global Earthquake Model (GEM) answers the need for an openly accessible risk management tool. GEM is an internationally sanctioned public private partnership initiated by the Organisation for Economic Cooperation and Development (OECD) which will establish an authoritative standard for calculating and communicating earthquake hazard and risk, and will be designed to serve as the critical instrument to support decisions and actions that reduce earthquake losses worldwide. GEM will integrate developments on the forefront of scientific and engineering knowledge of earthquakes, at global, regional and local scale. The work is organized in three modules: hazard, risk, and socio-economic impact. The hazard module calculates probabilities of earthquake occurrence and resulting shaking at any given location. The risk module calculates fatalities, injuries, and damage based on expected shaking, building vulnerability, and the distribution of population and of exposed values and facilities. The socio-economic impact module delivers tools for making educated decisions to mitigate and manage risk. GEM will be a versatile online tool, with open source code and a map-based graphical interface. The underlying data will be open wherever possible, and its modular input and output will be adapted to multiple user groups: scientists and engineers, risk managers and decision makers in the public and private sectors, and the public-at- large. GEM will be the first global model for seismic risk assessment at a national and regional scale, and aims to achieve broad scientific participation and independence. Its development will occur in a

  17. Differentialtherapie mit Kalziumantagonisten

    Directory of Open Access Journals (Sweden)

    Dörffel Y

    2004-01-01

    Full Text Available Der antihypertensive Effekt der Kalziumantagonisten ist bei allen Altersgruppen und Rassen seit längerem erwiesen. Darüber hinaus sind verschiedene andere positive Wirkungen dokumentiert, wie z. B. die Verbesserung der Endothelfunktion, Reduktion der Atheroskleroseprogression in der A. carotis, Reduktion der linksventrikulären und der arteriolären Hypertrophie sowie eine Verbesserung der arteriellen Compliance. Kalziumantagonisten verschlechtern nicht den Lipid- oder Glukosestoffwechsel. Für den Einsatz in der Praxis ist die Kenntnis der Heterogenität der Substanzklasse mit sich daraus ableitenden Vor- und Nachteilen sowie unterschiedlichen Indikationen von großer Relevanz. Den Prototypen der Non-Dihydropyridine Verapamil (chem. Phenylalkylamin und Diltiazem (chem. Benzothiazepine steht die umfangreiche Substanzklasse der Dihydropyridine (DHP gegenüber. Zu den DHPs zählen neben dem Prototyp Nifedipin die neueren Substanzen wie Nitrendipin, Nisoldipin, Amlodipin, Felodipin, Lacidipin und Lercanidipin. DHPs sind in erster Linie Vasodilatatoren, die durch eine Reduktion des peripheren vaskulären Widerstandes den arteriellen Blutdruck senken. Insbesondere bei älteren Präparaten mit schnellem Wirkungseintritt, wie z. B. beim unretardierten Nifedipin, einem DHP der ersten Generation, kann eine autonome Gegenregulation ausgelöst werden. Bei den modernen DHPs mit längerer Wirkungsdauer und bei den Non-DHPs ist dieser Effekt bedeutend abgeschwächt oder gar nicht mehr nachweisbar. In mehreren prospektiven, randomisierten und placebokontrollierten Studien konnte bei Patienten mit isolierter systolischer Hypertonie eine Reduktion der Schlaganfallrate dokumentiert werden (Syst-Eur, Syst-China, signifikante Unterschiede bezüglich Mortalität und Morbidität ergaben sich im Vergleich mit anderen Antihypertensiva (Diuretika, Betablocker, ACE-Hemmer nicht (STOP-2, INSIGHT, NORDIL, ALLHAT, INVEST. In der meist erforderlichen antihypertensiven

  18. Leading a successful iGEM team.

    Science.gov (United States)

    Materi, Wayne

    2012-01-01

    The International Genetically Engineered Machines (iGEM) competition allows undergraduate teams to develop projects in synthetic biology within the context of a large, international Jamboree. Organizing and managing a successful iGEM team is an exercise in advanced agile project development. While many of the principles applicable to such teams are derived from management of agile software teams, iGEM presents several unique challenges.

  19. Coating mit Biopolymeren

    Science.gov (United States)

    Kumpugdee-Vollrath, Mont; Nunthanid, Jurairat; Sriamornsak, Pornsak

    Biopolymere sind Polymere, die in der Natur vorkommen bzw. mit einigen Prozessen weiter bearbeitet werden, sodass sie für bestimmte Zwecke eingesetzt werden können. Häufig sind sie durch ihre Bioabbaubarkeit, Biokompatibilität und nicht vorhandene bzw. geringe Toxizität von Interesse für den Einsatz in der Medizin bzw. Pharmazie.

  20. The GEMS-2 SEIS Experiment

    Science.gov (United States)

    Tillier, S.; De Raucourt, S.; Mimoun, D.; Lognonne, P.; Giardini, D.; Christensen, U. R.; Pike, W. T.; Banerdt, B.; Laudet, P.; Kerjean, L.; Hurst, K. J.; Zweifel, P.; Mance, D.; Roll, R.; Bierwirth, M.; Gagnepain-Beyneix, J.; Nibut, T.; Robert, O.; Gabsi, T.; Pot, O.; Lecomte, B.; Schibler, P.; Mocquet, A.; Garcia, R.

    2011-12-01

    The SEIS experiment is the primary payload of the Geophysical Monitoring Station (GEMS) Mission Proposal, submitted to NASA in the frame of the 2010 Discovery program, and recently selected for the phase A study. The objective of the GEMS SEIS experiment is the determination of the deep internal structure of Mars. In particular, geophysical parameters of first importance, such as the state (liquid/solid) and size of the core, as well as structure of the mantle and shape of discontinuities will be determined by the experiment. It will measure seismic activity in a very broad band of signal, from the tidal frequencies (0.05 mHz) up to the short period frequencies (50 Hz), to address the widest range of scientific questions, from the state of the inner core to the meteoritic rate measurement. Infrasound, which might be associated to dust devils and atmospheric discharge, will be also monitored. The instrument integrates a Very Broad Band (VBB) 3 axis seismometer, completed by another trihedron of MEMS short period seismometers, environmental sensors for pressure, wind and temperature, and an infrasound sensor is additionally considered. The sensors will be deployed on the Martian ground by a robotic arm from the Phoenix lander platform and protected by a wind and thermal shield. The sensor assembly, which contains all seismic sensors, the leveling system, as well as house-keeping and temperature measurements, will be deployed on the soil in order to allow the best possible mechanical coupling with the ground motion. Thanks to the wind and thermal shield, together with the sensors' specific containers (vacuum sphere for VBBs), long term VBB bias will be protected from both temperature and pressure variations (as well as passively compensated), allowing the sensor to operate in the rough Martian thermal environment. A dedicated electronics will manage the overall experiment and ultra-low noise, space qualified 24 bits A/D converters will perform the acquisition. The

  1. Research and Development of GEM Foil at CIAE

    Institute of Scientific and Technical Information of China (English)

    LI; Xiao-mei; ZHOU; Jing; HU; Shou-yang; SHAN; Chao; JIAN; Si-yu; YE; Li; BAI; Xin-zhan; ZHOU; Shu-hua

    2012-01-01

    <正>China Institute of Atomic Energy has signed the "License Agreement for Manufacturing and Commercialisation of Gem Foils and Gem Based Products Licensee" with CERN, and got the technical assistance from CERN. The base material of GEM foil is ultrathin, non-adhesive copper on polyimide substrate, which can be purchased from CERN and other companies. The manufacture of GEM foil is

  2. Characterization of the GEM foil materials

    CERN Document Server

    Benussi, L; Saviano, G; Muhammad, S; Piccolo, D; Raffone, G; Caponero, M; Passamonti, L; Pierluigi, D; Russo, A; Primavera, F; Cerbelli, S; Lalli, A; Valente, M; Ferrini, M; Teissandier, B; Taborelli, M; Parvis, M; Grassini, S; Tirilló, J; Sarasini, F; Franchi, A V

    2015-01-01

    Systematic studies on the GEM foil material are performed to measure the moisture diffusion rate and saturation level. These studies are important because the presence of this compound inside the detector's foil can possibly change its mechanical and electrical properties and, in such a way, the detector performance can be affected. To understand this phenomenon, a model is developed with COMSOL Multhiphysics v. 4.3, which described the adsorption and diffusion within the geometry of GEM foil, the concentration profiles and the time required to saturate the foil. The COMSOL model is verified by experimental observations on a GEM foil sample. This note will describe the model and its experimental verification results.

  3. Commercial and Cost Effective Production of Gas Electron Multiplier (GEM) Foils

    Energy Technology Data Exchange (ETDEWEB)

    Woody, Craig

    2009-03-31

    The nuclear and high energy physics research community is constantly searching for new and improved tracking and radiation detectors. The introduction of micropattern detectors has opened new opportunities for improving the rate capabilities, as well as the spatial and time resolution of particle detectors in these applications. GEM detectors in particular have received enormous interest for use in detectors planned for a number of new and upgraded experiments at many different research facilities. These include both the STAR and PHENIX experiments at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory, experiments at the Thomas Jefferson National Laboratory, Oak Ridge National Laboratory, and at the future electron-positron Linear Collider. At the present time, CERN is not able to supply foils in sufficient quantities to accommodate the needs of these experiments. Compounding this problem, there is a strong interest in GEM foils for numerous other applications, such as in astrophysics, medical imaging and detectors for homeland security. It would therefore be of significant benefit to the research community to develop a commercial source of GEM foils for all of these applications. Tech-Etch is in a unique position to develop this technology for commercial use. Tech-Etch has not only experience in numerous related high precision etched Kapton® products, but it also has strong ties with several research institutions (namely Brookhaven, Yale and MIT) that can help develop and evaluate the performance of the GEM foils produced at Tech-Etch. Additionally, since Tech-Etch is a small company, it also has the capability to produce a large variety of part configurations, as well as the flexibility to shift production methods, equipment, and chemistry to optimize the GEM foil manufacturing process without being constrained by existing work running on high volume continuous coil equipment.

  4. Geschwister eines ausserfamilär platzierten Kindes: Handlungsempfehlungen für Beistandspersonen mit Fokus auf die systemische Familienarbeit unter Berücksichtigung der Besonderheit der Geschwisterbeziehung

    OpenAIRE

    Lötscher, Jana; Heimgartner, Sylvie

    2016-01-01

    Die vorliegende Fachliteraturarbeit befasst sich mit Handlungsempfehlungen für Beistandspersonen, welche eine Beistandschaft gemäss Art. 308 Abs. 1 und 2 ZGB nach Aufhebung des Aufenthaltsbestimmungsrechts gemäss Art. 310 Abs. 1 ZGB für ein Kind aus einer Familie führen. Die Geschwister des ausserfamiliär platzierten Kindes verbleiben dabei im Familiensystem. Diese besondere Konstellation erfordert von der Beistandsperson eine systemische Arbeitsweise, um der gesamten Familie gerecht zu werde...

  5. Development of large-area glass GEM

    Energy Technology Data Exchange (ETDEWEB)

    Mitsuya, Yuki, E-mail: yukimitsuya@sophie.q.t.u-tokyo.ac.jp [Department of Nuclear Engineering and Management, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8654 (Japan); Fujiwara, Takeshi [Research Institute for Measurement and Analytical Instrumentation, National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 2, 1-1-1 Umezono, Tsukuba, Ibaraki 305-8568 (Japan); Fushie, Takashi [HOYA Corporation, 3280 Nakamaru, Nagasaka-cho, Hokuto-city, Yamanashi 408-8550 (Japan); Maekawa, Tatsuyuki [Toshiba Corporation, 8 Shinsugita-cho, Isogo-ku, Yokohama-city, Kanagawa 235-8523 (Japan); Takahashi, Hiroyuki [Department of Nuclear Engineering and Management, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8654 (Japan)

    2015-09-21

    We have developed a new gaseous radiation detector, referred to as the Glass GEM (G-GEM). The G-GEM is composed of a photosensitive etching glass (PEG3) substrate from HOYA Corporation, Japan. Since a large-area detector is required for imaging device applications, we newly developed a large-area G-GEM prototype with a sensitive area of 280×280 mm{sup 2}. In this study, we investigated its basic characteristics and confirmed that it worked properly and had sufficient uniformity across the entire sensitive area. It had high gas gain of up to approximately 7700, along with good energy resolution of 26.2% (FWHM) for a 5.9-keV X-ray with a gas mixture of Ar (90%) and CH4 (10%). The gain variation across the sensitive area was almost within the range of ±10%.

  6. GEM Building Taxonomy (Version 2.0)

    Science.gov (United States)

    Brzev, S.; Scawthorn, C.; Charleson, A.W.; Allen, L.; Greene, M.; Jaiswal, Kishor; Silva, V.

    2013-01-01

    This report documents the development and applications of the Building Taxonomy for the Global Earthquake Model (GEM). The purpose of the GEM Building Taxonomy is to describe and classify buildings in a uniform manner as a key step towards assessing their seismic risk, Criteria for development of the GEM Building Taxonomy were that the Taxonomy be relevant to seismic performance of different construction types; be comprehensive yet simple; be collapsible; adhere to principles that are familiar to the range of users; and ultimately be extensible to non-buildings and other hazards. The taxonomy was developed in conjunction with other GEM researchers and builds on the knowledge base from other taxonomies, including the EERI and IAEE World Housing Encyclopedia, PAGER-STR, and HAZUS. The taxonomy is organized as a series of expandable tables, which contain information pertaining to various building attributes. Each attribute describes a specific characteristic of an individual building or a class of buildings that could potentially affect their seismic performance. The following 13 attributes have been included in the GEM Building Taxonomy Version 2.0 (v2.0): 1.) direction, 2.)material of the lateral load-resisting system, 3.) lateral load-resisting system, 4.) height, 5.) date of construction of retrofit, 6.) occupancy, 7.) building position within a block, 8.) shape of the building plan, 9.) structural irregularity, 10.) exterior walls, 11.) roof, 12.) floor, 13.) foundation system. The report illustrates the pratical use of the GEM Building Taxonomy by discussing example case studies, in which the building-specific characteristics are mapped directly using GEM taxonomic attributes and the corresponding taxonomic string is constructed for that building, with "/" slash marks separating attributes. For example, for the building shown to the right, the GEM Taxonomy string is: DX1/MUR+CLBRS+MOCL2/LWAL3/

  7. Does Comet WILD-2 contain Gems?

    Science.gov (United States)

    Chi, M.; Ishii, H.; Dai, Z. R.; Toppani, A.; Joswiak, D. J.; Leroux, H.; Zolensky, M.; Keller, L. P.; Browning, N. D.

    2007-01-01

    It is expected that Comet Wild-2 dust should resemble anhydrous carbon-rich, chondritic porous (CP) interplanetary dust particles (IDPs) collected in the stratosphere because some CP IDPs are suspected to be from comets. The rarity of carbonaceous grains and presolar silicates, as well as the presence of high-temperature inner solar nebula minerals in the Wild-2 sample (e.g. osbornite and melilite), appear incompatible with most CP IDPs. However, it is premature to draw firm conclusions about the mineralogy of comet Wild-2 because only approx. 1% of the sample has been examined. The most abundant silicates in CP IDPs are GEMS (glass with embedded metal and sulfides). Nonsolar O isotopic compositions confirm that at least some GEMS in IDPs are presolar amorphous silicates. The presence or absence of GEMS in the Wild-2 sample is important because it addresses, (a) the relationship between CP IDPs and comets, and (b) the hypothesis that other GEMS in IDPs formed in the solar nebula. Here we show that most of the GEMSlike materials so far identified in Stardust aerogel were likely impact generated during collection. At the nanometer scale, they are compositionally and crystallographically distinct from GEMS in IDPs.

  8. Single electron multiplication distribution in GEM avalanches

    CERN Document Server

    Laszlo, Andras; Kiss, Gabor; Varga, Dezso

    2016-01-01

    In this paper measurement results and experimental methodology is presented on the determination of multiplication distributions of avalanches in GEM foils initiated by a single electron. The measurement relies on the amplification of photoelectrons by the GEM under study, which is subsequently amplified in an MWPC. The intrinsic detector resolution, namely the sigma over mean ratio of this distribution is also elaborated. Small gain dependence of the avalanche size is observed in the range of net effective gain of 15 to 100. The distribution has an exponentially decaying tail at large amplitudes, whereas the applied working gas is seen to have a well visible effect on the shape of the multiplication distribution at low amplitudes; or equivalently, the working gas has an influence on the intrinsic detector resolution of GEMs via suppression of the low amplitude responses. A sigma over mean ratio down to 0.75 was reached using neon based mixture, whereas other gases provided an intrinsic detector resolution cl...

  9. GEM Module Design for the ILD TPC

    CERN Document Server

    Benke, T; Münnich, A; Zenker, K

    2013-01-01

    A Time Projection Chamber (TPC) using micro-pattern gas detectors is planned as the main tracking device for a detector at the next Linear Collider. A novel support structure for Gas Electron Multipliers (GEMs), which minimizes the material and improves the flatness of the foils, has been developed and tested with multiple GEM modules in a large TPC prototype at DESY. Reducing dead material at the GEM module boundaries improves the field homogeneity. In addition, it was shown in simulation that a field shaping ring at the border of the module can improve the charge collection in regions with non-homogeneous fields. This shaping wire was integrated into the module design and a successful test beam campaign with three modules has been carried out. First results regarding resolution and field distortions will be discussed.

  10. Die Last mit der Lust

    Directory of Open Access Journals (Sweden)

    Lutz Sauerteig

    2004-03-01

    Full Text Available Robert Jütte legt mit Lust ohne Last eine umfassende, allgemeinverständliche und spannend zu lesende Geschichte der Empfängnisverhütung von der Antike bis in die unmittelbare Gegenwart vor.

  11. MIT-CSR XIS Project

    Science.gov (United States)

    1998-01-01

    This report outlines the proposers' progress toward MIT's contribution to the X-Ray Imaging Spectrometer (XIS) experiment on the Japanese ASTRO-E mission. The report discusses electrical system design, mechanical system design, and ground support equipment.

  12. Spillerum og mit eget rum

    DEFF Research Database (Denmark)

    2014-01-01

    Undervisningsmaterialet Spillerum udviklet som APP til Ipad med interaktive muligheder. Spillerum som APP - et interaktivt undervisningsmateriale, hvor man ud over at bruge det originale materiale Spillerum elektronisk kan skabe sit eget billedbaserede rum "Mit eget rum" som udgangspunkt for dialog....

  13. Verbalsuffixe mit Liquida

    Directory of Open Access Journals (Sweden)

    Marina Zorman

    1995-12-01

    Full Text Available Der vorliegende Beitrag stellt eine Zusammenfassung bzw. vervollständigte Ver­ sion einiger Kapitel der Magisterarbeit der Autorin mit dem Titel Expressive Wort­ bildung beim Verb (Ältere, wahrscheinlich ererbte Kombinationen -V/C- + -r/l- - das Grundtypus -dr- - im Slowenischen dar. Die wesentlichen Erkenntnisse der Arbeit hinsichtlich der morphologischen und semantischen Gestalt derartiger Verben, ihrer dialektologischen Verbreitung und der Genese, Funktion und Austauschbarkeit dieser Suffixe sollen unter dem Titel "Ekspresivne glagolske pripone tipa -V/C + -r/l-" in den "Razprave XV II. razreda SAZU" (Dissertationes Classis II, XV. Ljubljana, Academia scientiarium et artium Slovenica (in Druck veröffentlicht werden, deshalb werden sie hier nur so weit aufgenommen, wie das für das Verständnis des behandelten Gegen­ stands unbedingt notwendig ist. Eingehender werden Fragen erortert, die im erwähnten Artikel nicht behandelt werden, die jedoch auch für andere Linguisten interessant sein könnten. So ist der vorliegende Beitrag in vier Teile gegliedert

  14. Neutron beam imaging with GEM detectors

    Science.gov (United States)

    Albani, G.; Croci, G.; Cazzaniga, C.; Cavenago, M.; Claps, G.; Muraro, A.; Murtas, F.; Pasqualotto, R.; Perelli Cippo, E.; Rebai, M.; Tardocchi, M.; Gorini, G.

    2015-04-01

    Neutron GEM-based detectors represent a new frontier of devices in neutron physics applications where a very high neutron flux must be measured such as future fusion experiments (e.g. ITER Neutral beam Injector) and spallation sources (e.g. the European Spallation source). This kind of detectors can be properly adapted to be used both as beam monitors but also as neutron diffraction detectors that could represent a valid alternative for the 3He detectors replacement. Fast neutron GEM detectors (nGEM) feature a cathode composed by one layer of polyethylene and one of aluminium (neutron scattering on hydrogen generates protons that are detected in the gas) while thermal neutron GEM detectors (bGEM) are equipped with a borated aluminium cathode (charged particles are generated through the 10B(n,α)7Li reaction). GEM detectors can be realized in large area (1 m2) and their readout can be pixelated. Three different prototypes of nGEM and one prototype of bGEM detectors of different areas and equipped with different types of readout have been built and tested. All the detectors have been used to measure the fast and thermal neutron 2D beam image at the ISIS-VESUVIO beamline. The different kinds of readout patterns (different areas of the pixels) have been compared in similar conditions. All the detectors measured a width of the beam profile consitent with the expected one. The imaging property of each detector was then tested by inserting samples of different material and shape in the beam. All the samples were correctly reconstructed and the definition of the reconstruction depends on the type of readout anode. The fast neutron beam profile reconstruction was then compared to the one obtained by diamond detectors positioned on the same beamline while the thermal neutron one was compared to the imaged obtained by cadmium-coupled x-rays films. Also efficiency and the gamma background rejection have been determined. These prototypes represent the first step towards the

  15. The GEMS-2 Seis Experiment

    Science.gov (United States)

    Mimoun, D.; de Raucourt, S.; Lognonne, P.; Giardini, D.; Christensen, U. R.; Gagnepain-Beyneix, J.; Pike, T.; Nebut, T.; Tillier, S.; Robert, O.; Gabsi, T.; Pot, O.; Lecomte, B.; Escande, N.; Mocquet, A.; Zweifel, P.; Mance, D.; Roll, R.; Bierwirth, M.

    2010-12-01

    of data will be made on the basis of raw compressed data, plus an excerpt of the high frequency events of the day. The proposed instrument has been developed up to PDR in the frame of the ExoMars Humbold payload. Most critical parts have been tested, including shock tests for pivot, electronics components and displacement sensors. TRL 6 is expected at the end of 2011. SEIS has been proposed onboard the GEMS Mission Proposal, submitted to NASA in the frame of the 2010 Discovery AO.

  16. MIT's interferometer CST testbed

    Science.gov (United States)

    Hyde, Tupper; Kim, Ed; Anderson, Eric; Blackwood, Gary; Lublin, Leonard

    1990-12-01

    The MIT Space Engineering Research Center (SERC) has developed a controlled structures technology (CST) testbed based on one design for a space-based optical interferometer. The role of the testbed is to provide a versatile platform for experimental investigation and discovery of CST approaches. In particular, it will serve as the focus for experimental verification of CSI methodologies and control strategies at SERC. The testbed program has an emphasis on experimental CST--incorporating a broad suite of actuators and sensors, active struts, system identification, passive damping, active mirror mounts, and precision component characterization. The SERC testbed represents a one-tenth scaled version of an optical interferometer concept based on an inherently rigid tetrahedral configuration with collecting apertures on one face. The testbed consists of six 3.5 meter long truss legs joined at four vertices and is suspended with attachment points at three vertices. Each aluminum leg has a 0.2 m by 0.2 m by 0.25 m triangular cross-section. The structure has a first flexible mode at 31 Hz and has over 50 global modes below 200 Hz. The stiff tetrahedral design differs from similar testbeds (such as the JPL Phase B) in that the structural topology is closed. The tetrahedral design minimizes structural deflections at the vertices (site of optical components for maximum baseline) resulting in reduced stroke requirements for isolation and pointing of optics. Typical total light path length stability goals are on the order of lambda/20, with a wavelength of light, lambda, of roughly 500 nanometers. It is expected that active structural control will be necessary to achieve this goal in the presence of disturbances.

  17. Gravitational field modes GEM 3 and 4

    Science.gov (United States)

    Lerch, F. J.; Wagner, C. A.; Putney, B. H.; Sandson, M. L.; Brownd, J. E.; Richardson, J. A.; Taylor, W. A.

    1972-01-01

    A refinement in the satellite geopotential solution for a Goddard Earth Model (GEM 3) was obtained. The solution includes the addition of two low inclination satellites, SAS at 3 deg and PEOLE at 15 deg, and is based upon 27 close earth satellites containing some 400,000 observations of electronic, laser, and optical data. In addition, a new combination satellite/gravimetry solution (GEM 4) was derived. The new model includes 61 center of mass tracking station locations with data from GRARR, Laser, MOTS, Baker-Nunn, and NWL Tranet Doppler tracking sites. Improvement was obtained for the zonal coefficients of the new models and is shown by tests on the long period perturbations of the orbits. Individual zonal coefficients agree very closely among different models that contain low inclination satellites. Tests of models with surface gravity data show that the GEM 3 satellite model has significantly better agreement with the gravimetry data than the GEM 1 satellite model, and that it also has better agreement with the gravimetry data than the 1969 SAO Standard Earth 2 model.

  18. Study on Inclusions in Natural and Synthetic Gems

    Institute of Scientific and Technical Information of China (English)

    李兆麟

    2001-01-01

    The characteristics of inclusions in natural and synthetic gems are distinct owing to their different forming mechanisms and can be utilized to distinguish gems from different locali ties. In addition, intensive studies on inclusion characteristics of natural gems could identify their geographical origins and provide valuable information on gem synthesis. In this paper syn thetic gems (synthetic star-spangled sapphire and emerald) and natural gems from various loca tions including natural sapphire from Thailand and Australia, and natural aquamerine from Mu fushan, Hunan Province, and Ailaoshan, Yunnan Province, were selected for the comparative study of inclusions. Significant research results have been achieved, thus providing the impor tant basis for distinguishing natural from synthetic gems.

  19. Europa Imaging Highlights during GEM

    Science.gov (United States)

    1998-01-01

    During the two year Galileo Europa Mission (GEM), NASA's Galileo spacecraft will focus intensively on Jupiter's intriguing moon, Europa. This montage shows samples of some of the features that will be imaged during eight successive orbits. The images in this montage are in order of increasing orbit from the upper left (orbit 11) to the lower right (orbit 19).DESCRIPTIONS AND APPROXIMATE RESOLUTIONSTriple bands and dark spots1.6 kilometers/pixelConamara Chaos1.6 kilometers/pixelMannan'an Crater1.6 kilometers/ pixelCilix1.6 kilometers/pixelAgenor Linea and Thrace Macula2 kilometers/pixelSouth polar terrain2 kilometers/pixelRhadamanthys Linea1.6 kilometers/pixelEuropa plume search7 kilometers/pixel1. Triple bands and dark spots were the focus of some images from Galileo's eleventh orbit of Jupiter. Triple bands are multiple ridges with dark deposits along the outer margins. Some extend for thousands of kilometers across Europa's icy surface. They are cracks in the ice sheet and indicate the great stresses imposed on Europa by tides raised by Jupiter, as well as Europa's neighboring moons, Ganymede and Io. The dark spots or 'lenticulae' are spots of localized disruption.2. The Conamara Chaos region reveals icy plates which have broken up, moved, and rafted into new positions. This terrain suggests that liquid water or ductile ice was present near the surface. On Galileo's twelfth orbit of Jupiter, sections of this region with resolutions as high as 10 meters per picture element will be obtained.3. Mannann'an Crater is a feature newly discovered by Galileo in June 1996. Color and high resolution images (to 40 meters per picture element) from Galileo's fourteenth orbit of Jupiter will offer a close look at the crater and help characterize how impacts affect the icy surface of this moon.4. Cilix, a large mound about 1.5 kilometers high, is the center of Europa's coordinate system. Its concave top and what may be flow like features to the southwest of the mound are

  20. Europa Imaging Highlights during GEM

    Science.gov (United States)

    1998-01-01

    During the two year Galileo Europa Mission (GEM), NASA's Galileo spacecraft will focus intensively on Jupiter's intriguing moon, Europa. This montage shows samples of some of the features that will be imaged during eight successive orbits. The images in this montage are in order of increasing orbit from the upper left (orbit 11) to the lower right (orbit 19).DESCRIPTIONS AND APPROXIMATE RESOLUTIONSTriple bands and dark spots1.6 kilometers/pixelConamara Chaos1.6 kilometers/pixelMannan'an Crater1.6 kilometers/ pixelCilix1.6 kilometers/pixelAgenor Linea and Thrace Macula2 kilometers/pixelSouth polar terrain2 kilometers/pixelRhadamanthys Linea1.6 kilometers/pixelEuropa plume search7 kilometers/pixel1. Triple bands and dark spots were the focus of some images from Galileo's eleventh orbit of Jupiter. Triple bands are multiple ridges with dark deposits along the outer margins. Some extend for thousands of kilometers across Europa's icy surface. They are cracks in the ice sheet and indicate the great stresses imposed on Europa by tides raised by Jupiter, as well as Europa's neighboring moons, Ganymede and Io. The dark spots or 'lenticulae' are spots of localized disruption.2. The Conamara Chaos region reveals icy plates which have broken up, moved, and rafted into new positions. This terrain suggests that liquid water or ductile ice was present near the surface. On Galileo's twelfth orbit of Jupiter, sections of this region with resolutions as high as 10 meters per picture element will be obtained.3. Mannann'an Crater is a feature newly discovered by Galileo in June 1996. Color and high resolution images (to 40 meters per picture element) from Galileo's fourteenth orbit of Jupiter will offer a close look at the crater and help characterize how impacts affect the icy surface of this moon.4. Cilix, a large mound about 1.5 kilometers high, is the center of Europa's coordinate system. Its concave top and what may be flow like features to the southwest of the mound are

  1. Robotisches Elektromobil mit kamerabasiertem Autonomieansatz

    OpenAIRE

    2011-01-01

    Autonomes Fahren erfährt in den vergangenen Jahren durch verschiedene Forschungsprojekte ein gesteigertes öffentliches Interesse. Dabei werden meist herkömmliche Pkw mit großem Aufwand umgebaut und mit Dachaufbauten voller Sensorik bestückt. Der Vormarsch der Elektromobilität bietet die Chance für grundlegend neue Fahrzeugkonzepte. Löst man sich von klassischen Ansätzen, so ist es möglich, die Autonomie von Anfang an in die Automobilarchitektur hinsichtlich IT- und Sensor-Systemen, Energieman...

  2. R&D of Commercially Manufactured Large GEM Foils

    CERN Document Server

    Posik, M

    2015-01-01

    Many experiments are currently using or proposing to use large area GEM foils in their detectors, which is creating a need for commercially available GEM foils. Currently CERN is the only main distributor of GEM foils, however with the growing interest in GEM technology keeping up with the increasing demand for GEM foils will be difficult. Thus the commercialization of GEM foils has been established by Tech-Etch Inc. of Plymouth, MA, USA using the single-mask technique, which is capable of producing GEM foils over a meter long. To date Tech-Etch has successfully manufactured 10 $\\times$ 10 cm$^2$ and 40 $\\times$ 40 cm$^2$ GEM foils. We will report on the electrical and geometrical properties, along with the inner and outer hole diameter size uniformity of these foils. Furthermore, Tech-Etch has now begun producing even larger GEM foils of 50 $\\times$ 50 cm$^2$, and are currently looking into how to accommodate GEM foils on the order of one meter long. The Tech-Etch foils were found to have excellent electrica...

  3. Gas electron multipliers. Development of large area GEMS and spherical GEMS

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Serge Duarte

    2011-08-15

    Gaseous radiation detectors have been a crucial part of high-energy physics instrumentation since the 1960s, when the first multiwire proportional counters were built. In the 1990s the first micropattern gas detectors (MPGDS) saw the light; with sub-millimeter feature sizes these novel detectors were faster and more accurate than their predecessors. The gas electron multiplier (GEM) is one of the most successful of these technologies. It is a charge multiplication structure made from a copper clad polymer foil, pierced with a regular and dense pattern of holes. I describe the properties and the application of GEMs and GEM. detectors, and the research and development I have done on this technology. Two of the main objectives were the development of large area GEMs ({proportional_to}m{sup 2}) for particle physics experiments and GEMs with a spherical shape for X-ray or neutron diffraction detectors. Both have been realized, and the new techniques involved are finding their way to applications in research and industry. (orig.)

  4. Thick GEM versus thin GEM in two-phase argon avalanche detectors

    CERN Document Server

    Bondar, A; Grebenuk, A; Pavlyuchenko, D; Tikhonov, Y; Breskin, Amos

    2008-01-01

    The performance of thick GEMs (THGEMs) was compared to that of thin GEMs in two-phase Ar avalanche detectors, in view of their potential application in coherent neutrino-nucleus scattering, dark-matter search and in other rare-event experiments. The detectors comprised a 1 cm thick liquid-Ar layer followed by either a double-THGEM or a triple-GEM multiplier, operated in the saturated vapor above the liquid phase. Three types of THGEMs were studied: those made of G10 and Kevlar and that with resistive electrodes (RETHGEM). Only the G10-made THGEM showed a stable performance in two-phase Ar with gains reaching 3000. Successful operation of two-phase Ar avalanche detectors with either thin- or thick-GEM multipliers was demonstrated at low detection thresholds, of 4 and 20 primary electrons respectively. Compared to the triple-GEM the double-THGEM multiplier yielded slower anode signals; this allowed applying a pulse-shape analysis to effectively reject noise signals. Noise rates of both multipliers were evaluate...

  5. Gas Electron Multipliers: Development of large area GEMs and spherical GEMs

    CERN Document Server

    Duarte Pinto, Serge; Brock, Ian

    2011-01-01

    Gaseous radiation detectors have been a crucial part of high-energy physics instrumentation since the 1960s, when the first multiwire proportional counters were built. In the 1990s the first micropattern gas detectors (MPGDs) saw the light; with sub-millimeter feature sizes these novel detectors were faster and more accurate than their predecessors. The gas electron multiplier (GEM) is one of the most successful of these technologies. It is a charge multiplication structure made from a copper clad polymer foil, pierced with a regular and dense pattern of holes. I will describe the properties and the application of GEMs and GEM detectors, and the research and development I have done on this technology. Two of the main objectives were the development of large area GEMs (~m^2) for particle physics experiments and GEMs with a spherical shape for x-ray or neutron diffraction detectors. Both have been realized, and the new techniques involved are finding their way to applications in research and industry.

  6. X-Ray Polarimetry with GEMS

    Science.gov (United States)

    Strohmayer, Tod

    2011-01-01

    The polarization properties of cosmic X-ray sources are still largely unexplored. The Gravity and Extreme Magnetism SMEX (GEMS) will carry out the first sensitive X-ray polarization survey of a wide range of sources including; accreting compact objects (black holes and neutron stars), AGN, supernova remnants, magnetars and rotation-powered pulsars. GEMS employs grazing-incidence foil mirrors and novel time-projection chamber (TPC) polarimeters leveraging the photoelectric effect to achieve high polarization sensitivity in the 2 - 10 keV band. I will provide an update of the project status, illustrate the expected performance with several science examples, and provide a brief overview of the data analysis challenges

  7. GEM - A novel gaseous particle detector

    CERN Document Server

    Meinschad, T

    2005-01-01

    The work carried out within the framework of this Ph.D. deals with the construction of gaseous prototype detectors using Gas Electron Multiplier electrodes for the amplification of charges released by ionizing particles. The Gas Electron Multiplier (GEM) is a thin metal-clad polymer foil, etched with a high density of narrow holes, typically 50-100mm-2. On the application of a potential difference between the conductive top and bottom sides each hole acts as independent proportional counter. This new fast device permits to reach large amplification factors at high rates with a strong photon and ion-mediated feedback suppression due to the avalanche confinement in the GEM-holes. Here, in particular studies have been performed, which should prove, that the GEM-technology is applicable for an efficient measurement of single Cherenkov photons. These UV-photons can be detected in different ways. An elegant solution to develop large area RICH-detectors is to evaporate a pad-segmented readout-cathode of a multi-wire...

  8. Triple GEM tracking detectors for COMPASS

    CERN Document Server

    Ketzer, B; Dehmelt, K; Ehlers, J; Friedrich, J M; Grube, B; Kappler, S; Konorov, I; Paul, S; Placci, Alfredo; Ropelewski, Leszek; Sauli, Fabio

    2002-01-01

    The small area tracker of COMPASS, a high-luminosity fixed target experiment at CERN's SPS, includes a set of 20 large-size ($31\\times 31\\,\\cm^2$) Gas Electron Multiplier (GEM) detectors. Based on gas amplification in three cascaded GEM foils, these devices permit to obtain high gain and good spatial resolution even at very high particle fluxes. A two-coordinate projective readout yields, for each track, highly correlated signal amplitudes on both projections, allowing to resolve multiple hits in high occupancy regions close to the central deactivated area of $5\\,\\cm$ diameter. At the same time the material exposed to the beam is minimized. Splitting the amplification in three cascaded stages permits to achieve a gain of $\\sim 8000$, necessary for efficient ($>98\\%$) detection of minimum ionizing particles on both coordinates, already at relatively moderate voltages across individual GEM foils. As a consequence, the probability of a gas discharge to occur when a heavily ionizing particle enters the detector v...

  9. Study of X-ray Imaging of GEM Detector

    Institute of Scientific and Technical Information of China (English)

    LI; Xiao-mei; HU; Shou-yang; JIAN; Si-yu; ZHOU; Jing; LI; Xing-long; LIANG; Hao; ZHOU; Shu-hua

    2015-01-01

    A 10cm×10cm GEM detector made by 3GEM foils was used in the X-ray imaging experiment.2-D strips readout mode was used and each dimension has 256channels with a pitch of 400micrometer.APV25front-end readout chip was introduced in the detector,and the backplane connectors were improved in order to adapt the electronics with GEM detector.Since each

  10. Study of etching processes in the GEM detectors

    CERN Document Server

    Zavazieva, Darina

    2016-01-01

    Gaseous Electron Multiplier (GEM) detectors are known to operate stably at high gains and high particle fluxes. Though, at very high gains and fluxes it was observed that the insulating polyimide layer between the GEM electrodes gets etched, changing the original shape of the hole, and therefore varying the gain and the energy resolution of the detector. The idea of the project to observe degradation effect of the GEM foils during the Triple GEM detector operation in extreme conditions under X-ray radiation.

  11. Mit Rechten am rechten Ort?

    OpenAIRE

    Bräuß, Katharina

    2010-01-01

    Kann pädagogisch sinnvoll mit rechtsextremen Jugendlichen in einer Gedenkstätte für die Opfer des Nationalsozialismus gearbeitet werden? Diese Frage steht im Zentrum der vorliegenden Arbeit, die sich im interdisziplinären Feld von Erinnerungs- und Gedenkstättenpädagogik, Rechtsextremismusforschung und pädagogischer Intervention/Prävention gegenüber Rassismus und Rechtsextremismus bewegt.

  12. Mit der Technik auf du

    OpenAIRE

    Gleitsmann, Rolf-Jürgen; Kunze, Rolf-Ulrich

    2017-01-01

    Im Vordergrund auch dieses dritten Bandes mit Technikessays steht die Bildinterpretation und die Erschließung von Bildquellen für die kontextualisierende, sozialkonstruktivistische Kulturgeschichte der Technik, die bislang noch wenig oder gar nicht Gegenstand historischer Betrachtung waren: u. a. der Graphiken von Carl G. Evers aus den 1950er Jahren, amerikanischer und deutscher Modellbahnzeitschriften, von Industriewerbung und einem Verkehrsbilderbuch. Zeitlich liegt der Schwerpunkt auf der ...

  13. Analysis of Mechanical Properties for GEM Foil

    CERN Document Server

    Chin, Yuk Ming

    2016-01-01

    In view of new assembly technique of the GEM detector; in which three foils stack is stretched to get the uniform gaps among the foils. We studied the mechanical properties of the foil material. We conditioned the samples in different environments to make them extra dry and wet. As holes are the major source of the charge amplification their deformation can effect the detector performance. Therefore in our studies we also studied at which level of the stress the holes deformation is seen. These tensile and holes deformation studies can help to optimize the stress during detector assembly.

  14. Development of lactococcal GEM-based pneumococcal vaccines

    NARCIS (Netherlands)

    Audouy, Sandrine A. L.; van Selm, Saskia; van Roosmalen, Maarten L.; Post, Eduard; Kanninga, Rolf; Neef, Jolanda; Estevao, Silvia; Nieuwenhuis, Edward E. S.; Adrian, Peter V.; Leenhouts, Kees; Hermans, Peter W. M.

    2007-01-01

    We report the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae, in which three pneumococcal proteins were displayed on the surface of a non-recombinant, killed Lactococcus lactis-derived delivery system, called Gram-positive Enhancer Matrix (GEM). The GEM particles

  15. Development of lactococcal GEM-based pneumococcal vaccines.

    NARCIS (Netherlands)

    Audouy, S.A.; Selm, S. van; Roosmalen, M.L. van; Post, E.; Kanninga, R.; Neef, J.; Estevao, S.; Nieuwenhuis, E.E.; Adrian, P.V.; Leenhouts, K.; Hermans, P.W.M.

    2007-01-01

    We report the development of a novel protein-based nasal vaccine against Streptococcus pneumoniae, in which three pneumococcal proteins were displayed on the surface of a non-recombinant, killed Lactococcus lactis-derived delivery system, called Gram-positive Enhancer Matrix (GEM). The GEM particles

  16. The Ozone Layer. UNEP/GEMS Environment Library No. 2.

    Science.gov (United States)

    United Nations Environment Programme, Nairobi (Kenya).

    Since the United Nations Environment Program (UNEP) was created, more than a dozen years ago, public understanding of the environmental issues confronting our planet has increased enormously. The Global Environment Monitoring System (GEMS) has provided several environmental assessments. The aim of the UNEP/GEMS Environment Library is to provide…

  17. Research and Development of Commercially Manufactured Large GEM Foils

    CERN Document Server

    Posik, M

    2015-01-01

    With future experiments proposing detectors that utilize very large-area GEM foils, there is a need for commercially available GEM foils. Double-mask etching techniques pose a clear limitation in the maximum size of GEM foils. In contrast, single-mask techniques developed at CERN would allow one to overcome those limitations. However with interest in GEM foils increasing and CERN being the only main distributor, keeping up with the demand for GEM foils will be difficult. Thus the commercialization of GEMs has been established by Tech-Etch of Plymouth, MA, USA using single-mask techniques. We report on the electrical and geometrical properties, along with the inner and outer hole diameter size uniformity of 10 $\\times$ 10 cm$^2$ and 40$\\times$40 cm$^2$ GEM foils. The Tech-Etch foils were found to have excellent electrical properties. The measured mean optical properties were found to reflect the desired parameters and are consistent with those measured in double-mask GEM foils, and show good hole diameter unif...

  18. Aktuelles aus der Forschung mit menschlichen embryonalen Stammzellen (Mit dem Jahresbericht 2004 der Zentralen Ethikkommission für Stammzellenforschung

    Directory of Open Access Journals (Sweden)

    Beier HM

    2005-01-01

    Full Text Available Im internationalen Diskurs über die Forschung mit menschlichen embryonalen Stammzellen und die Perspektiven, regenerative Therapien zu entwickeln, fanden sich in jüngster Zeit bemerkenswerte Beiträge, auf die wir hier zurückgreifen. In den aufstrebenden Forschungsnationen Südkorea, Taiwan, Singapur und China läuft ein enormer Wettbewerb um die umfangreichsten Forschungsressourcen und die Führung in der embryonalen Stammzellforschung ab. In Europa und in den USA investieren Wissenschaftler Zeit, Forschungsmittel und intellektuelle Kapazität in die Suche nach Wegen, humane embryonale Stammzellen herzustellen, ohne menschliche Eizellen und Embryonen für diese Verfahren opfern zu müssen. In Deutschland finden solche Bemühungen ein positives Echo, weil das Gesetz es verbietet, embryonale Stammzellen aus verwaisten Blastozysten, sog. überzähligen Embryonen, herzustellen. Dem Stammzellgesetz gemäß kann in Deutschland nur unter Ausnahmebedingungen an menschlichen embryonalen Stammzellen geforscht werden. Wissenschaftler dürfen nach Prüfung und Genehmigung eines speziellen Projektantrages durch das Robert-Koch-Institut menschliche embryonale Stammzell-Linien von bestimmten, lizensierten, ausländischen Herstellern importieren. Allerdings müssen diese Zell-Linien vor dem Stichtag, dem 1.1.2002, hergestellt worden sein. Die Zentrale Ethik-Kommission für Stammzellenforschung (ZES, die das Robert-Koch-Institut im Auftrag der Bundesregierung berät, berichtet jedes Jahr über ihre Arbeit. Im zweiten Teil dieses Artikels wird mit freundlicher Genehmigung des Bundesministeriums für Gesundheit und Soziale Sicherheit der ZES-Jahresbericht 2004 veröffentlicht.

  19. Diskriminierung von Enantiomeren mit chiralen Selektoren

    OpenAIRE

    Würthner, Stefan

    2007-01-01

    Die vorliegende Dissertation befasst sich mit der systematischen Aufklärung von zwischenmolekularen Wirt-Gast-Wechselwirkungen von Arzneistoffen mit Cyclodextrinen. In einem sich trichterförmig verengenden Erkenntnisprozeß wird im ersten Schritt eine breite Datenbasis von Kapillarelektrophorese-Daten von 86 chiralen Arzneistoffen mit 3 nativen CDs (alpha, beta und gamma) sowie 11 CD-Derivaten gewonnen. Sowohl die Trennfaktoren der Enantiomeren (alpha_m) als auch die Retardierungsfaktoren (R_m...

  20. Gems of combinatorial optimization and graph algorithms

    CERN Document Server

    Skutella, Martin; Stiller, Sebastian; Wagner, Dorothea

    2015-01-01

    Are you looking for new lectures for your course on algorithms, combinatorial optimization, or algorithmic game theory?  Maybe you need a convenient source of relevant, current topics for a graduate student or advanced undergraduate student seminar?  Or perhaps you just want an enjoyable look at some beautiful mathematical and algorithmic results, ideas, proofs, concepts, and techniques in discrete mathematics and theoretical computer science?   Gems of Combinatorial Optimization and Graph Algorithms is a handpicked collection of up-to-date articles, carefully prepared by a select group of international experts, who have contributed some of their most mathematically or algorithmically elegant ideas.  Topics include longest tours and Steiner trees in geometric spaces, cartograms, resource buying games, congestion games, selfish routing, revenue equivalence and shortest paths, scheduling, linear structures in graphs, contraction hierarchies, budgeted matching problems, and motifs in networks.   This ...

  1. Development and performance of large-scale triple GEM detectors for CMS

    CERN Document Server

    Bouhali, Othmane; Abi Akl, M.; Argamaingaud, C.; Aspell, P.; Assran, Y.; Bally, S.; Ban, Y.; Barria, P.; Benussi, L.; Bhopatkar, V.; Bianco, S.; Bos, J.; Bouhali, O.; Cai, J.; Calabria, C.; Castaneda, A.; Cauwenbergh, S.; Celik, A.; Christiansen, J.; Colafranceschi, S.; Colaleo, A.; Conde Garcia, A.; De Lentdecker, G.; De Oliveira, R.; de Robertis, G.; Dildick, S.; Ferry, S.; Flanagan, W.; Gilmore, J.; Gutierrez, A.; Hoepfner, K.; Hohlmann, M.; Kamon, T.; Karchin, P.E.; Khotilovich, V.; Krutelyov, S.; Loddo, F.; Maerschalk, T.; Magazzu, G.; Maggi, M.; Maghrbi, Y.; Marchioro, A.; Marinov, A.; Merlin, J.A.; Nuzzo, S.; Oliveri, E.; Philipps, B.; Piccolo, D.; Postema, H.; Radi, A.; Radogna, R.; Raffone, G.; Ranieri, A.; Rodrigues, A.; Ropelewski, L.; Safonov, A.; Sakharov, A.; Salva, S.; Saviano, G.; Sharma, A.; Tatarinov, A.; Teng, H.; Turini, N.; Twigger, J.; Tytgat, M.; van Stenis, M.; Verhagen, E.; Yang, Y.; Zaganidis, N.; Zenoni, F.

    2013-01-01

    The international CMS GEM collaboration is studying the feasibility of upgrading the CMS forward muon system by adding layers of triple GEM based detectors. After successful tests of small size tripe-GEM chambers in the period of 2010-2011, the collaboration has designed, built and tested full size GEM chambers for the upgrade purpose. We report on results from test beam and simulation that were conducted to study the performance of the GEM chambers.

  2. GEM detector development for CBM experiment at FAIR

    Energy Technology Data Exchange (ETDEWEB)

    Dubey, A.K., E-mail: anand@vecc.gov.in [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700 064 (India); Prakash, A. [Banaras Hindu University, Varanasi 221 005 (India); Chattopadhyay, S.; Ganti, M.S.; Singaraju, R.; Saini, J. [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700 064 (India); Singh, B.K. [Banaras Hindu University, Varanasi 221 005 (India); Viyogi, Y.P. [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700 064 (India)

    2013-08-01

    A GEM-based detector system is being developed at VECC, Kolkata, to be used for muon tracking in the proposed Compressed Baryonic Experiment (CBM) at the upcoming FAIR facility at GSI, Darmstadt. We have built and successfully tested several multi-GEM prototypes with radioactive sources and cosmic muons. We report the details of the R and D at VECC in terms of fabrication, assembly and the subsequent tests of the prototype chambers.

  3. YIP: Generic Environment Models (GEMs) for Agile Marine Autonomy

    Science.gov (United States)

    2013-09-30

    1 DISTRIBUTION STATEMENT A. Approved for public release; distribution is unlimited. YIP : Generic Environment Models (GEMs) for Agile Marine...2013 2. REPORT TYPE 3. DATES COVERED 00-00-2013 to 00-00-2013 4. TITLE AND SUBTITLE YIP : Generic Environment Models (GEMs) for Agile Marine...2010 ONR YIP Award Sponsor: Office of Naval Research Recipient: Fumin Zhang Institution: Georgia Institute of Technology Award: 2010 Lockheed

  4. Turnover Rate Simulation Using GEM Detector on Neutron Radiography

    Institute of Scientific and Technical Information of China (English)

    SHAN; Chao; LI; Xiao-mei; HU; Shou-yang; ZHOU; Jing; JIAN; Si-yu; BAI; Xin-zhan; YE; Li; ZHOU; Shu-hua

    2012-01-01

    <正>With the advantages of high counting rate, high resolution ratio and high compatibility, GEM (Gas Electron Multiplier) detector has becoming the hot topic in the field of gas detector. Using GEM on neutron radiography, we need a suitable neutron converter. By the action on the converter and ingoing neutron, the outgoing particles could be an alpha or proton, which are charged particles. The charged

  5. Research and Development of Commercially Manufactured Large GEM Foils

    CERN Document Server

    Posik, M

    2014-01-01

    The recently completed Forward GEM Tracker (FGT) of the STAR experiment at RHIC took advantage of commercially produced GEM foils based on double-mask chemical etching techniques. With future experiments proposing detectors that utilize very large-area GEM foils, there is a need for commercially available GEM foils. Double-mask etching techniques pose a clear limitation in the maximum size. In contrast, single-mask techniques developed at CERN would allow one to overcome those limitations. We report on results obtained using 10 $\\times$ 10 cm$^2$ and 40$\\times$40 cm$^2$ GEM foils produced by Tech-Etch Inc. of Plymouth, MA, USA using single-mask techniques and thus the beginning for large GEM foil production on a commercial basis. A quality assurance procedure has been established through electrical and optical analyses via leakage current measurements and an automated high-resolution CCD scanner. The Tech-Etch foils show excellent electrical properties with leakage currents typically measured below 1 nA. The ...

  6. 3D Observation of GEMS by Electron Tomography

    Science.gov (United States)

    Matsuno, Junya; Miyake, Akira; Tsuchiyama, Akira; Nakamura-Messenger, Keiko; Messenger, Scott

    2014-01-01

    Amorphous silicates in chondritic porous interplanetary dust particles (CP-IDPs) coming from comets are dominated by glass with embedded metal and sulfides (GEMS). GEMS grains are submicron-sized rounded objects (typically 100-500) nm in diameter) with anaometer-sized (10-50 nm) Fe-Ni metal and sulfide grains embedded in an amorphous silicate matrix. Several formation processes for GEMS grains have been proposed so far, but these models are still being debated [2-5]. Bradley et al. proposed that GEMS grains are interstellar silicate dust that survived various metamorphism or alteration processes in the protoplanetary disk and that they are amorphiation products of crystalline silicates in the interstellar medium by sputter-deposition of cosmic ray irradiation, similar to space weathering [2,4]. This consideration is based on the observation of nano-sized crystals (approximately 10 nm) called relict grains in GEMS grains and their shapes are pseudomorphs to the host GEMS grains. On the other hand, Keller and Messenger proposed that most GEMS formed in the protoplanetary disk as condensates from high temperature gas [3,5]. This model is based on the fact that most GEMS grains have solar isotopic compositions and have extremely heterogeneous and non-solar elemental compositions. Keller and Messenger (2011) also reported that amorphous silicates in GEMS grains are surrounded by sulfide grains, which formed as sulfidization of metallic iron grains located on the GEMS surface. The previous studies were performed with 2D observation by using transmission electron microscopy (TEM) or scanning TEM (STEM). In order to understand the structure of GEMS grains described above more clearly, we observed 3D structure of GEMS grains by electron tomography using a TEM/STEM (JEM-2100F, JEOL) at Kyoto University. Electron tomography gives not only 3D structures but also gives higher spatial resolution (approximately a few nm) than that in conventional 2D image, which is restricted by

  7. Geothermal elastometric materials (GEM) program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hirasuna, A.R.; Bilyeu, G.D.; Davis, D.L.; Sedwick, R.A.; Stephens, C.A.; Veal, G.R.

    1979-07-01

    The primary program objective, to develop a geothermal packer elastomer to withstand 260/sup 0/C (500/sup 0/F) geothermal brine with 300 ppM H/sub 2/S, 1000 ppM CO/sub 2/, 25,000 ppM NaCl in aqueous solution for 24 hours, was successfully accomplished. In fact the requirement for one elastomer was exceeded, compounds from four elastomeric polymer systems were successfully developed to meet the GEM requirements providing good flexibility for various situations. Several secondary spin-offs also resulted. The compounds were developed for the casing packer seal application and it was demonstrated that these compounds are directly applicable to the static O-ring and other elastomer applications in similarly unusually severe environments. There is also indication based on drill bits seal tests that the basic compounds will be adaptable to high-temperature dynamic seal applications. Another secondary spin-off is a different conceptual approach to the thermal casing packer problem. This approach concentrates on minimizing the stresses subjected on the sealing element. Since it is fundamentally different, it has a good chance of advancing thermal packer capability in a revolutionary manner as opposed to an evolutionary manner.

  8. The Student Experiment on the GEMS Mission

    Science.gov (United States)

    Allured, Ryan; Kaaret, Philip; Prieskorn, Zachary; Maxwell, Alicia

    2009-11-01

    The Gravity and Extreme Magnetism Small Explorer (GEMS) is an exciting new mission that will make X-ray polarization measurements of a large number of objects of different classes. The main instrument is sensitive in the 2-10keV band. Students at the University of Iowa are currently building a Bragg Reflection Polarimeter (BRP) that will supplement the main instrument by providing sensitivity at 500eV. The BRP consists of a multilayer crystal reflector, a proportional counter, and electronics. The multilayer crystal will be used to reflect the soft X-rays from the telescope beam to the proportional counter. In addition to having a high reflectivity at 500eV, the reflector must transmit the high-energy X-rays efficiently, so as not to interfere with the main instrument. The proportional counter will use charge division to sense position in one dimension, and will contain anti-coincidence anodes to reject background events. The BRP will make polarization measurements by measuring the intensity of observed radiation as the spacecraft rotates around the telescope axis. The primary use for low energy polarization measurements is to fix the inclination angle of the accretion disks of black holes.

  9. Photovoltaik Hybrid-Solarzellen mit Nanopartikeln

    Science.gov (United States)

    Leute, Angelika

    2004-09-01

    Die organische Photovoltaik auf der Basis halbleitender Polymere bietet eine kostengünstige Alternative zu Solarzellen aus Silizium. Allerdings weisen die organischen Materialien relativ schlechte Ladungstransporteigenschaften auf. Hybrid-Solarzellen, in denen Polymere mit geeigneten anorganischen Halbleitern kombiniert sind, besitzen einerseits die praktischen Vorteile der Organik und andererseits die hohe Elektronenbeweglichkeit der anorganischen Materialien. Wissenschaftler der Technischen Universität Eindhoven haben kürzlich Hybrid-Solarzellen vorgestellt, die aus einem halbleitenden Polymer mit Zinkoxid-Nanopartikeln bestehen.

  10. Hamlet er manden i mit liv

    DEFF Research Database (Denmark)

    Rösing, Lilian Munk

    2009-01-01

    Hamlet er manden i mit liv. Min elskede. Jeg har en drøm om at frelse ham. At redde ham ud af sin mors soveværelse og ind i mit. Væk fra det ødipale Helvede han befinder sig i, fastlåst mellem et svin af en faderskikkelse (Claudius) og en alt for idealiseret far (gamle Hamlet), vågende over sin m...

  11. Correlation slopes of GEM / CO, GEM / CO2, and GEM / CH4 and estimated mercury emissions in China, South Asia, Indochinese Peninsula, and Central Asia derived from observations in northwest and southwest China

    Science.gov (United States)

    Fu, X. W.; Zhang, H.; Lin, C.-J.; Feng, X.; Zhou, L. X.; Fang, S. X.

    2014-09-01

    Correlation analysis between atmospheric mercury (Hg) and other trace gases are useful for identification of sources and constraining regional estimated Hg emissions. Emissions of Hg in Asia contribute significantly to the global budget of atmospheric Hg. However, due to the lack of reliable data on the source strength, large uncertainties remain in the emission inventories of Hg in Asia. In the present study, we calculated the correlation slopes of GEM / CO, GEM / CO2, and GEM / CH4 for mainland China, South Asia, Indochinese Peninsula, and Central Asia using the ground-based observations at three remote sites in northwest and southwest China, and applied the values to estimate GEM emissions in the four source regions. The geometric mean of the GEM / CO correlation slopes for mainland China, South Asia, Indochinese Peninsula, and Central Asia were 7.3 ± 4.3, 7.8 ± 6.4, 7.8 ± 5.0, and 13.4 ± 9.5 pg m-3 ppb-1, respectively. The values in the same source regions were 240 ± 119, 278 ± 164, 315 ± 289 pg m-3 ppm-1 for the GEM / CO2 correlation slopes; and 33.3 ± 30.4, 27.4 ± 31.0, 23.5 ± 15.3, and 20.5 ± 10.0 pg m-3 ppb-1 for the GEM / CH4 correlation slopes, respectively. These values were the first reported correlation slopes of GEM / CO, GEM / CO2, and GEM / CH4 in four important source regions of Asia except the GEM / CO ratios in mainland China. The correlation slopes of GEM / CO, GEM / CO2 and GEM / CH4 in Asia were relatively higher than those observed in Europe, North America and South Africa, which may highlight GEM emissions from non-ferrous smelting, mercury mining, natural sources and historical deposited mercury (re-emission) in Asia. Using the observed GEM / CO and GEM / CO2 slopes, and the recently reported emission inventories of CO and CO2, the annual GEM emissions in mainland China, South Asia, Indochinese Peninsula, and Central Asia were estimated to be in the ranges of 1071-1187 t, 340-470 t, 125 t, and 54-90 t, respectively. The estimate

  12. Correlation slopes of GEM / CO, GEM / CO2, and GEM / CH4 and estimated mercury emissions in China, South Asia, Indochinese Peninsula, and Central Asia derived from observations in northwest and southwest China

    Directory of Open Access Journals (Sweden)

    X. W. Fu

    2014-09-01

    Full Text Available Correlation analysis between atmospheric mercury (Hg and other trace gases are useful for identification of sources and constraining regional estimated Hg emissions. Emissions of Hg in Asia contribute significantly to the global budget of atmospheric Hg. However, due to the lack of reliable data on the source strength, large uncertainties remain in the emission inventories of Hg in Asia. In the present study, we calculated the correlation slopes of GEM / CO, GEM / CO2, and GEM / CH4 for mainland China, South Asia, Indochinese Peninsula, and Central Asia using the ground-based observations at three remote sites in northwest and southwest China, and applied the values to estimate GEM emissions in the four source regions. The geometric mean of the GEM / CO correlation slopes for mainland China, South Asia, Indochinese Peninsula, and Central Asia were 7.3 ± 4.3, 7.8 ± 6.4, 7.8 ± 5.0, and 13.4 ± 9.5 pg m−3 ppb−1, respectively. The values in the same source regions were 240 ± 119, 278 ± 164, 315 ± 289 pg m−3 ppm−1 for the GEM / CO2 correlation slopes; and 33.3 ± 30.4, 27.4 ± 31.0, 23.5 ± 15.3, and 20.5 ± 10.0 pg m−3 ppb−1 for the GEM / CH4 correlation slopes, respectively. These values were the first reported correlation slopes of GEM / CO, GEM / CO2, and GEM / CH4 in four important source regions of Asia except the GEM / CO ratios in mainland China. The correlation slopes of GEM / CO, GEM / CO2 and GEM / CH4 in Asia were relatively higher than those observed in Europe, North America and South Africa, which may highlight GEM emissions from non-ferrous smelting, mercury mining, natural sources and historical deposited mercury (re-emission in Asia. Using the observed GEM / CO and GEM / CO2 slopes, and the recently reported emission inventories of CO and CO2, the annual GEM emissions in mainland China, South Asia, Indochinese Peninsula, and Central Asia were estimated to be in the ranges of 1071–1187 t, 340–470 t, 125 t, and 54

  13. Application of Large Scale GEM for Digital Hadron Calorimetry

    CERN Document Server

    Yu, J; Park, K; Park, S; Sosebee, M; Tran, N; White, A P

    2011-01-01

    The High Energy Physics group of the University of Texas at Arlington Physics Department has been developing Gas Electron Multiplier (GEM) detectors for use as the sensitive gap detector in digital hadron calorimeters (DHCAL) for the future International Linear Collider. In this study, two kinds of prototype GEM detectors have been tested. One has 30x30 cm2 active area double GEM structure with a 3 mm drift gap, a 1 mm transfer gap and a 1 mm induction gap. The other one has two 2x2 cm2 GEM foils in the amplifier stage with a 5 mm drift gap, a 2 mm transfer gap and a 1 mm induction gap. We present characteristics of these detectors obtained using high-energy charged particles, cosmic ray muons and 106Ru and 55Fe radioactive sources. From the 55Fe tests, we observed two well-separated X-ray emission peaks and measured the chamber gain to be over 6500 with a high voltage of 395 V across each GEM electrode. Both the spectra from cosmic rays and the 106Ru fit well to Landau distributions as expected from minimum ...

  14. The Bisa GEM-Mars GCM

    Science.gov (United States)

    Neary, Lori; Daerden, Frank

    2013-04-01

    GEM-Mars is a three-dimensional general circulation model of the Mars atmosphere extending from the surface to approximately 170 km based on the latest version of the GEM (Global Environmental Mesoscale) model, the operational data assimilation and weather forecasting system for Canada [Côté et al., 1998]. The dynamical core is an implicit two-time-level semi-Lagrangian scheme on an Arakawa C-grid with a terrain-following, log-hydrostatic-pressure vertical coordinate discretized on a Charney-Phillips grid. The model has both a hydrostatic and non-hydrostatic formulation, providing a single platform for simulations on a variety of horizontal scales. The model code is fully parallelized using OMP and MPI. The GCM includes the relevant physical processes such as CO2 condensation, planetary boundary layer mixing, gravity wave drag and surface parameterizations. A simple water cycle, basic gas-phase chemistry and passive tracers are also included in the model. Because of the vertical extent of the model, UV heating, non-LTE effects and molecular diffusion are also included. Dust is prescribed using the MGS scenario for total opacities and a Conrath profile shape. In the dust radiative transfer code, dust optical properties are based on the Wolff et al [2006, 2009] data. Temperatures in the lower and middle atmosphere have been evaluated using TES [Smith, 2004] and MCS [Kleinbohl et al. 2009] data. Winds and atmospheric circulation (mass stream functions) have been compared with the literature and show a good correspondence to other Mars GCMs. In parallel, active lifting and settling of size-distributed dust has also been implemented. The soil model has been improved to better match surface and near-surface temperatures from the Viking Landers, Phoenix [Davy et al. 2010], and TES. Near-surface winds and friction velocities have been compared with the literature and show reasonable performance. Condensation of CO2 in surface ice has been validated using CO2 ice mass

  15. Definition des Hochrisikopatienten und therapeutische Optionen beim Patienten mit ST-Hebungsmyokardinfarkt

    Directory of Open Access Journals (Sweden)

    Metzler B

    2010-01-01

    Full Text Available Die möglichst frühzeitige Identifikation derjenigen Myokardinfarktpatienten, die einem hohen Mortalitätsrisiko ausgesetzt sind, ist von besonderem klinischen und auch gesundheitsökonomischen Interesse. Eine Risikoabschätzung ist mit mehreren vorliegenden Risiko- Scores, wie beispielsweise dem CADILLAC-, dem GRACE- und dem TIMI-Score, leicht und genau möglich. Diese Scores berücksichtigen verschiedene klinische Parameter. Durch eine zuletzt veröffentlichte Metaanalyse zum Einsatz der intraaortalen Ballonpumpe beim Hochrisikopatienten mit Myokardinfarkt, bei der sich kein signifikanter Überlebensvorteil, vielmehr sogar eine höhere Blutungswahrscheinlichkeit, bei dieser bisher als Klasse-I-Indikation geführten Therapieform gezeigt hat, weist auf die Notwendigkeit hin, die vorliegenden, oft kontroversiellen Studienresultate der Einzelstudien einer genauen und kritischen Evaluierung zu unterwerfen. Andererseits zeigt es aber auch die Schwierigkeit der oft nicht sauber durchführbaren Randomisierung bei intensivmedizinischen Studien auf. Weiters hat die Stratifizierung der Patienten gemäß ihres Risikos gezeigt, dass der in diversen Studien gezeigte Vorteil der primären perkutanen Koronarintervention (p-PCI im Wesentlichen auf die Hochrisikopatienten beschränkt ist. Die genaue und frühzeitige Risikoabschätzung ermöglicht eine daraus ableitbare bestmögliche Therapiestrategie für den individuellen Patienten. Zusätzlich können damit die vorhandenen medizinischen Ressourcen sinnvoll genützt werden.

  16. GEM400: A front-end chip based on capacitor-switch array for pixel-based GEM detector

    Science.gov (United States)

    Li, H. S.; Jiang, X. S.; Liu, G.; Wang, N.; Sheng, H. Y.; Zhuang, B. A.; Zhao, J. W.

    2012-03-01

    The upgrade of Beijing Synchrotron Radiation Facility (BSRF) needs two-dimensional position-sensitive detection equipment to improve the experimental performance. Gas Electron Multiplier (GEM) detector, in particular, pixel-based GEM detector has good application prospects in the domain of synchrotron radiation. The read-out of larger scale pixel-based GEM detector is difficult for the high density of the pixels (PAD for collecting electrons). In order to reduce the number of cables, this paper presents a read-out scheme for pixel-based GEM detector, which is based on System-in-Package technology and ASIC technology. We proposed a circuit structure based on capacitor switch array circuit, and design a chip GEM400, which is a 400 channels ASIC. The proposed circuit can achieve good stability and low power dissipation. The chip is implemented in a 0.35μm CMOS process. The basic functional circuitry in ths chip includes analog switch, analog buffer, voltage amplifier, bandgap and control logic block, and the layout of this chip takes 5mm × 5mm area. The simulation results show that the chip can allow the maximum amount of input charge 70pC on the condition of 100pF external integrator capacitor. Besides, the chip has good channel uniformity (INL is better than 0.1%) and lower power dissipation.

  17. Gaseous Electron Multiplier (GEM), foil holes deformation studies

    CERN Document Server

    Suhaj, Adam; CERN. Geneva. PH Department

    2015-01-01

    GEM detectors play an important role in the upcoming high-luminosity LHC upgrade in 2018 where they will be exposed to high doses of radiation in the muon endcap region. A series of tensile tests were performed on neutron irradiated and non-irradiated GEM foils where the shape of the holes was thoroughly examined. It was found that the GEM foil does not deform much at lower loads but the deformation gets exponentially bigger after applying more than a 60 N force. Both sets of samples behaved similarly at lower loads up to 40 N after which the holes of the irradiated samples started to deform more rapidly than the non-irradiated ones. The failure point of the non-irradiated samples occurred consistently at around 135 N while the irradiated samples experienced failure at around 85 N with two outliers failing at 120 and 135 N.

  18. Environmentally compatible next generation green energetic materials (GEMs).

    Science.gov (United States)

    Talawar, M B; Sivabalan, R; Mukundan, T; Muthurajan, H; Sikder, A K; Gandhe, B R; Rao, A Subhananda

    2009-01-30

    This paper briefly reviews the literature work reported on the environmentally compatible green energetic materials (GEMs) for defence and space applications. Currently, great emphasis is laid in the field of high-energy materials (HEMs) to increase the environmental stewardship along with the deliverance of improved performance. This emphasis is especially strong in the areas of energetic materials, weapon development, processing, and disposal operations. Therefore, efforts are on to develop energetic materials systems under the broad concept of green energetic materials (GEMs) in different schools all over the globe. The GEMs program initiated globally by different schools addresses these challenges and establishes the framework for advances in energetic materials processing and production that promote compliance with environmental regulations. This review also briefs the principles of green chemistry pertaining to HEMs, followed by the work carried out globally on environmentally compatible green energetic materials and allied ingredients.

  19. Aging measurements with the gas electron multiplier (GEM)

    CERN Document Server

    Altunbas, M C; Kappler, S; Ketzer, B; Ropelewski, Leszek; Sauli, Fabio; Simon, F

    2003-01-01

    Continuing previous aging measurements with detectors based on the Gas Electron Multiplier (GEM), a $31\\times 31$cm$^2$ triple-GEM detector, as used in the small area tracking of the COMPASS experiment at CERN, was investigated. With a detector identical to those installed in the experiment, long-term, high-rate exposures to $8.9$keV X-ray radiation were performed to study its aging properties. In standard operation conditions, with Ar:CO$_2$ (70:30) filling and operated at an effective gain of $8.5\\cdot 10^3$, no change in gain and energy resolution is observed after collecting a total charge of 7mC/mm$^2$, corresponding to seven years of normal operation. This observation confirms previous results demonstrating the relative insensitivity of GEM detectors to aging, even when manufactured with common materials.

  20. Distinction of gem spinels from the himalayan mountain belt.

    Science.gov (United States)

    Malsy, Anna; Klemmb, Leonhard

    2010-01-01

    Gem spinel deposits in Myanmar, Vietnam and Tajikistan have their formation in association with Himalayan orogenesis. Gem-quality orange, pink, red and purple spinels from deposits at Mogok (Myanmar), Luc Yen (Vietnam), and Kuh-i-Lal (Tajikistan) have been investigated by 'standard' gemological testing and laser ablation inductively coupled plasma mass spectrometry (LA-ICP-MS). Microscopic examination yielded apatite and calcite inclusions together with octahedral negative crystals to be most frequently present in Mogok spinels. The presence of dislocation systems and titanite inclusions are indicative inclusion features for spinels from Luc Yen. Trace elements such as Ti, Fe, Ni, Zn, Zr and Sn differ slightly in spinels from the sources investigated. A distinction of spinels from these deposits is therefore possible by trace element chemistry. This is especially helpful for gem spinels, which often show few inclusions or completely lack inclusion features.

  1. Readout of TPC Tracking Chambers with GEMs and Pixel Chip

    Energy Technology Data Exchange (ETDEWEB)

    Kadyk, John; Kim, T.; Freytsis, M.; Button-Shafer, J.; Kadyk, J.; Vahsen, S.E.; Wenzel, W.A.

    2007-12-21

    Two layers of GEMs and the ATLAS Pixel Chip, FEI3, have been combined and tested as a prototype for Time Projection Chamber (TPC) readout at the International Linear Collider (ILC). The double-layer GEM system amplifies charge with gain sufficient to detect all track ionization. The suitability of three gas mixtures for this application was investigated, and gain measurements are presented. A large sample of cosmic ray tracks was reconstructed in 3D by using the simultaneous timing and 2D spatial information from the pixel chip. The chip provides pixel charge measurement as well as timing. These results demonstrate that a double GEM and pixel combination, with a suitably modified pixel ASIC, could meet the stringent readout requirements of the ILC.

  2. [Two Turkish manuscripts on gems (jauhar) and the treatment by means of gems].

    Science.gov (United States)

    Kutlar, F S

    2001-01-01

    Literary works of the genre called cevâhir-nâme or cevher-nâme are written in order to give information on how gems (cevher-jauhar) are formed, where they are found, their estimated values, how to distinguish them from the imitations, what their particular colours are and on their uses and harmful effects. These literary works are sometimes titled in accordance with the genre they belong to and sometimes they are given different titles. The literary works dealing with the subject of cevher are mostly written in prose and only a few of them are in verse. The Turkish versions of cevâhir-nâme texts started to be written in the 15th century. These texts, covering the earlier knowledge of medicine, give information on gems and perfumes; how they effect human health; and the way they should be used in medical treatment. Therefore, these texts should be discussed in relation with their place in the history of Turkish science. Two cevâhir-nâmes, which were translated into Turkish by Mustafâ bin Seydî and Za'îfî in the 15th and 16th centuries are still available. The translations by Mustafâ bin Seydî and Za'îfî, did not only convey the classical and medieval knowledge on cevhers to the contemporary readers, but they also confirm the fact that this information was a part of the Ottoman social life.

  3. Study of the characteristics of GEM detectors for the future FAIR experiment CBM

    Energy Technology Data Exchange (ETDEWEB)

    Biswas, S., E-mail: saikat.ino@gmail.com [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt 64291 (Germany); Abuhoza, A. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt 64291 (Germany); National Center for Mathematics and Physics, KACST, P.O. Box 6086, Riyadh 11442 (Saudi Arabia); Frankenfeld, U.; Hehner, J.; Schmidt, C.J. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt 64291 (Germany); Schmidt, H.R. [Eberhard-Karls-Universität, Tübingen (Germany); Träger, M. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt 64291 (Germany); Colafranceschi, S.; Marinov, A.; Sharma, A. [Physics Department, CERN - Geneva (Switzerland)

    2013-08-01

    Characteristics of triple GEM detector have been studied systematically. The variation of the effective gain and energy resolution of GEM with variation of the applied voltage has been measured with Fe{sup 55} X-ray source for different gas mixtures and with different gas flow rates. Long-term test of the GEM has also been performed.

  4. Study of the characteristics of GEM detectors for the future FAIR experiment CBM

    CERN Document Server

    Biswas, S; Frankenfeld, U; Hehner, J; Schmidt, C J; Schmidt, H R; Traeger, M; Colafranceschi, S; Marinov, A; Sharma, A

    2014-01-01

    Characteristics of triple GEM detector have been studied systematically. The variation of the effective gain and energy resolution of GEM with variation of the applied voltage has been measured with Fe55 X-ray source for different gas mixtures and with different gas flow rates. Long-term test of the GEM has also been performed.

  5. Dependence of Growing High-Quality Gem Diamonds on Growth Rates by Temperature Gradient Method

    Institute of Scientific and Technical Information of China (English)

    ZANG Chuan-Yi; JIA Xiao-Peng; REN Guo-Zhong; WANG Xian-Cheng

    2004-01-01

    @@ Using the temperature gradient method under high pressure and high temperature, we investigate the dependence of growing high-quality gem diamond crystals on the growth rates. It is found that the lower the growth rate of gem diamond crystals, the larger the temperature range of growing high-quality gem diamond crystals, and the easier the control of temperature.

  6. Neutron beam monitor based on a boron-coated GEM

    Institute of Scientific and Technical Information of China (English)

    周健荣; 李仪; 孙志嘉; 刘贲; 王艳凤; 杨桂安; 周良; 许虹; 董静; 杨雷

    2011-01-01

    A new thermal neutron beam monitor with a Gas Electron Multiplier (GEM) is developed to meet the needs of the next generation of neutron facilities. A prototype chamber has been constructed with two 100 mm×100 mm GEM foils. Enriched boron-10 is coated on

  7. Entrepreneurship in Ireland 2012: global entrepreneurship monitor (GEM)

    OpenAIRE

    Fitzsimons, Paula; O'Gorman, Colm

    2013-01-01

    Report on entrepreneurship in Ireland in the year 2012. Data used is the Global Entrepreneurship Monitor (GEM) data for Ireland and selected comparative countries. The report profiles entrepreneurs, reports on the rate of entrepreneurship in Ireland, discusses female entrepreneurship, and positions these results in the context of Irish entrepreneurship policy.

  8. The Greenhouse Gases. UNEP/GEMS Environment Library No. 1.

    Science.gov (United States)

    United Nations Environment Programme, Nairobi (Kenya).

    Since the United Nations Environment Program (UNEP) was created, more than a dozen years ago, public understanding of the environmental issues confronting our planet has increased enormously. The Global Environment Monitoring System (GEMS) has provided several environmental assessments including urban air pollution, climate modification,…

  9. gems: An R Package for Simulating from Disease Progression Models

    Directory of Open Access Journals (Sweden)

    Nello Blaser

    2015-03-01

    Full Text Available Mathematical models of disease progression predict disease outcomes and are useful epidemiological tools for planners and evaluators of health interventions. The R package gems is a tool that simulates disease progression in patients and predicts the effect of different interventions on patient outcome. Disease progression is represented by a series of events (e.g., diagnosis, treatment and death, displayed in a directed acyclic graph. The vertices correspond to disease states and the directed edges represent events. The package gems allows simulations based on a generalized multistate model that can be described by a directed acyclic graph with continuous transition-specific hazard functions. The user can specify an arbitrary hazard function and its parameters. The model includes parameter uncertainty, does not need to be a Markov model, and may take the history of previous events into account. Applications are not limited to the medical field and extend to other areas where multistate simulation is of interest. We provide a technical explanation of the multistate models used by gems, explain the functions of gems and their arguments, and show a sample application.

  10. The Gravity and Extreme Magnetism Small Explorer (GEMS)

    Science.gov (United States)

    Kallman, T. R.

    2011-01-01

    The Gravity and Extreme Magnetism Small Explorer (GEMS) was selected by NASA for flight in 2014 to make a sensitive search for X-ray polarization from a wide set of source classes, including stellar black holes, Seyfert galaxies and quasars, blazars, rotation and accretion-powered pulsars, magnetars, shell supernova remnants and pulsar wind nebulae. Among the primary scientific objectives are determining the effects of the spin of black holes and the geometry of supermassive black hole accretion, determining the configurations of the magnetic fields and the X-ray emission of magnetars, and determining the magnetic structure of the supernova shocks in which cosmic rays are accelerated. GEMS will observe 23 targets during a 16 month prime mission, in observations that will be able to reach predicted levels of polarization. The mission can be extended to provide a guest observer phase. The GEMS instrument has time projection chamber polarimeters with high 2-10 keV efficiency at the focus of thin foil mirrors. The 4.5 m focal length mirrors will be deployed on an extended boom. The spacecraft with the instrument is rotated with a period of about 10 minutes to enable measurement and correction of systematic errors. A small Bragg reflection soft X-ray experiment takes advantage of this rotation to obtain a measurement at 0.5 keV. The design of the GEMS instrument and the mission, the expected performance and the planned science program will be discussed.

  11. CMS Technical Design Report for the Muon Endcap GEM Upgrade

    CERN Document Server

    Colaleo, A; Sharma, A; Tytgat, M; CERN. Geneva. The LHC experiments Committee; LHCC

    2015-01-01

    This report describes both the technical design and the expected performance of the Phase-II upgrade, using Gas Electron Multiplier (GEM) detectors, of the first endcap station of the CMS muon system. The upgrade is targeted for the second long shutdown of the CERN LHC and is designed to improve the muon trigger and tracking performance at high luminosity. The GEM detectors will add redundancy to the muon system in the 1.6 < |η| < 2.2 pseudorapidity region, where the amount of detection layers is lowest while the background rates are highest and the bending of the muon trajectories due to the CMS magnetic field is small. GEM detectors have been identified as a suitable technology to operate in the high radiation environment present in that region. The first muon endcap station will be instrumented with a double layer of triple-GEM chambers in the 1.6 < |η| < 2.2 region. The detector front-end electronics uses the custom designed VFAT3 chip to provide both fast input for the level-1 muon trigger ...

  12. GEMS: underwater spectrometer for long-term radioactivity measurements

    Science.gov (United States)

    Sartini, Ludovica

    2010-05-01

    GEMS (Gamma Energy Marine Spectrometer) is a prototype of an autonomous radioactivity sensor for underwater measurements, developed in the framework of the KM3NeT Design Study (DS) EC project. The spectrometer is sensitive to gamma rays produced by 40K decays and it is also able to detect other natural (e.g., 238U, 232Th) and anthropogenic radionuclides (e.g. 137Cs). The decay of 40K, contained in sea salt, particulate and sediments, is one of the main sources of photon background in the underwater environment. GEMS was first calibrated in the laboratory using known sources, also in order to evaluate the performance of the instrument. In November 2008 GEMS was deployed at a depth of 3200 m in the area of Capo Passero (in the Ionian Sea) to acquire data autonomously. After recovery of the spectrometer six months later (May 2009) it was found that the instrument had worked within the specifications and acquired data over the full deployment period. These data allowed us to investigate over a long period the possible variations of activity at the Capo Passero site. GEMS is suitable to be used either in autonomous mode or as payload of seafloor observatories or vehicles.

  13. Hard Assets : The Returns on Rare Diamonds and Gems

    NARCIS (Netherlands)

    Renneboog, L.D.R.; Spaenjers, C.

    2011-01-01

    This paper examines the investment performance of diamonds and other gems (sapphires, rubies, and emeralds) over the period 1999-2010, using a novel data set of auction transactions. Between 1999 and 2010, the annualized real USD returns for white and colored diamonds equaled 6.4% and 2.9%, respecti

  14. Grosse Axiallager mit Hybridschmierung - Theoretische und experimentelle Betrachtungen

    DEFF Research Database (Denmark)

    Santos, Ilmar; Fuerst, Axel

    2003-01-01

    Der vorliegende Artikel praesentiert die Simulation eines grossen axialen Kippsegmentlagers unter Beruecksichtigung der hybriden Schmierung, d.h. gleichzeitige hydrodynamische und hydrostatische Schmierung. Ein Vergleich mit Messungen zeigt, dass fuer das betrachtete Lager mit 2,2 m Durchmesser d...

  15. Improvement in the geopotential derived from satellite and surface data /Gem 7 and 8/

    Science.gov (United States)

    Wagner, C. A.; Lerch, F. J.; Brownd, J. E.; Richardson, J. A.

    1977-01-01

    A refinement has been obtained in the earth's gravitational field by using satellite and surface data. In addition to a more complete treatment of data previously employed on 27 satellites, the new satellite solution Gem 7 (Goddard Earth Model 7) includes 64,000 laser measurements taken on seven satellites. Gem 7, containing 400 harmonic terms, is complete through degree and order 16. The companion solution Gem 8 combines the same satellite data as Gem 7 with surface gravimetry over 39% of the earth. Gem 8 is complete to degree and order 25. Extensive tests on data independent of the solution show that the undulations of the geoidal surface computed by Gem 7 have an accuracy of about 2.5 m (rms). The overall accuracy of the geoid calculated by Gem 8 is estimated to be about 4 m (rms). The new combination solution is the first to show signs of 'convection rolls' in the upper mantle below the Pacific Ocean.

  16. Deeskalation der Immuntherapie bei Patienten mit Multipler Sklerose

    OpenAIRE

    2016-01-01

    Die vorliegende Arbeit ist die erste, die sich mit der Frage beschäftigt, mit welcher zur Deeskalation eingesetzten Therapie nach Beendigung einer Eskalationstherapie mit Mitoxantron am besten Krankheitsstabilität erreicht werden kann bzw. ob Patienten-/Krankheitscharakteristika existieren, die eine bestimmte Nachfolge-Therapie favorisieren. Trotz neuer Behandlungsmöglichkeiten der hochaktiven MS mit Fingolimod, Natalizumab und Alemtuzumab hat Mitoxantron im klinischen Alltag nach wie vor ...

  17. MIT Lincoln Laboratory Annual Report 2009

    Science.gov (United States)

    2009-01-01

    function and managing the financial operations for the Laboratory, which include accounting services, financial planning and reporting, property...three-dimensional carbon nanotube - based nanoelectronics and mobile wireless networks, have been scheduled at the Laboratory. One technical...PROgRAM pei -lan Hsu, an MIt VI-A Master of engineering student working in the Advanced Silicon technology Group, explored the properties of graphene

  18. MIT professor wins major international math prize

    CERN Multimedia

    Allen, S

    2004-01-01

    Mathematicians Isadore Singer of MIT and Sir Michael Francis Atiyah of the University of Edinburgh will share an $875,000 award as winners of the second Abel Prize, which some hope will come to be seen as a Nobel Prize for math.

  19. Wrestling with Pedagogical Change: The TEAL Initiative at MIT

    Science.gov (United States)

    Breslow, Lori

    2010-01-01

    In the late 1990s, the physics department at the Massachusetts Institute of Technology (MIT) had a problem. The department was responsible for teaching the two required physics courses that are part of the General Institute Requirements (GIRs), MIT's core curriculum--Physics I (mechanics, or in MIT parlance, 8.01) and Physics II (electricity and…

  20. Analysis of GEM properties and development of a GEM support structure for the ILD time projection chamber

    Energy Technology Data Exchange (ETDEWEB)

    Hallermann, Lea

    2010-04-15

    In the concept of the International Large Detector (ILD), developed for the International Linear Collider (ILC) a Time Projection Chamber (TPC) is envisaged as main tracking detector. Such gaseous detectors have to be equipped with amplification devices in order to enlarge the amount of charge, which is set free by ionization caused by traversing charged particles. Micro Pattern Gas Detectors (MPGDs) will be used in the ILD TPC as amplification stage. In this thesis, Gas Electron Multipliers (GEMs) - one specific MPGD species - are analyzed concerning various properties. Effective gains and energy resolutions are compared for GEM foils produced by different manufacturers. A good understanding of these observables is obtained by interpretation of the results with the help of geometrical parameters. Height profile measurements of GEM foils have been performed for the first time and the impact of non perfect flat GEMs is analyzed, especially on dE/dx determination and drift field quality. The results emphasize the need of a flat installation of GEMs in TPCs. As a consequence, a new mounting device has been developed to ensure flatness and to provide a method to cover large readout areas, as in the ILD TPC, by introducing the least possible amount of dead material into the detector. The developed structure has been tested in a TPC protoype, taking cosmic muon data. The influence of the mounting on track reconstruction, single point resolution, tracking efficiency and dE/dx measurements is quantified. The developed mounting is applicable in a large scale TPC, if some design considerations are taken into account. (orig.)

  1. GEM voltage supply and real-time monitoring

    CERN Document Server

    Karaventzas, Vasilios Dimitris

    2015-01-01

    The operation of a GEM requires strong electrical fields that are able to initiate an electron avalanche. These electrical fields are generated by the application of high voltage in µm gaps. The scope of this project was to monitor the electrical parameters of the applied voltages, such as level and current flowing towards the detector. Therefore a real-time monitoring scheme was implemented. Additionally, a scheme for having all the voltages required for the operation of a GEM controllable, is proposed. The work conducted during this time-frame was targeted into developing the necessary parts for the operation of such device, whereas the integration of those into one functional circuit is to be conducted in a future work.

  2. GEMS: Underwater spectrometer for long-term radioactivity measurements

    Energy Technology Data Exchange (ETDEWEB)

    Sartini, Ludovica, E-mail: ludovica.sartini@ingv.i [Istituto Nazionale di Geofisica e Vulcanologia (INGV), Sect.Roma 2, Roma (Italy); Genoa University, Genoa (Italy); Simeone, Francesco; Pani, Priscilla [' Sapienza' University and Istituto Nazionale di Fisica Nucleare (INFN), Sect.Roma, Roma (Italy); Lo Bue, Nadia; Marinaro, Giuditta [Istituto Nazionale di Geofisica e Vulcanologia (INGV), Sect.Roma 2, Roma (Italy); Grubich, Andry; Lobko, Alexander [Institute for Nuclear Problems (INP), Belarus State University, Minsk (Belarus); Etiope, Giuseppe [Istituto Nazionale di Geofisica e Vulcanologia (INGV), Sect.Roma 2, Roma (Italy); Capone, Antonio [' Sapienza' University and Istituto Nazionale di Fisica Nucleare (INFN), Sect.Roma, Roma (Italy); Favali, Paolo [Istituto Nazionale di Geofisica e Vulcanologia (INGV), Sect.Roma 2, Roma (Italy); Gasparoni, Francesco; Bruni, Federico [Tecnomare S.p.A., Venice (Italy)

    2011-01-21

    GEMS (Gamma Energy Marine Spectrometer) is a prototype of an autonomous radioactivity sensor for underwater measurements, developed in the framework for a development of a submarine telescope for neutrino detection (KM3NeT Design Study Project). The spectrometer is highly sensitive to gamma rays produced by {sup 40}K decays but it can detect other natural (e.g., {sup 238}U,{sup 232}Th) and anthropogenic radio-nuclides (e.g., {sup 137}Cs). GEMS was firstly tested and calibrated in the laboratory using known sources and it was successfully deployed for a long-term (6 months) monitoring at a depth of 3200 m in the Ionian Sea (Capo Passero, offshore Eastern Sicily). The instrument recorded data for the whole deployment period within the expected specifications. This monitoring provided, for the first time, a continuous time-series of radioactivity in deep-sea.

  3. Large gem diamonds from metallic liquid in Earth's deep mantle.

    Science.gov (United States)

    Smith, Evan M; Shirey, Steven B; Nestola, Fabrizio; Bullock, Emma S; Wang, Jianhua; Richardson, Stephen H; Wang, Wuyi

    2016-12-16

    The redox state of Earth's convecting mantle, masked by the lithospheric plates and basaltic magmatism of plate tectonics, is a key unknown in the evolutionary history of our planet. Here we report that large, exceptional gem diamonds like the Cullinan, Constellation, and Koh-i-Noor carry direct evidence of crystallization from a redox-sensitive metallic liquid phase in the deep mantle. These sublithospheric diamonds contain inclusions of solidified iron-nickel-carbon-sulfur melt, accompanied by a thin fluid layer of methane ± hydrogen, and sometimes majoritic garnet or former calcium silicate perovskite. The metal-dominated mineral assemblages and reduced volatiles in large gem diamonds indicate formation under metal-saturated conditions. We verify previous predictions that Earth has highly reducing deep mantle regions capable of precipitating a metallic iron phase that contains dissolved carbon and hydrogen.

  4. GEM detectors development for radiation environment: neutron tests and simulations

    Science.gov (United States)

    Chernyshova, Maryna; Jednoróg, Sławomir; Malinowski, Karol; Czarski, Tomasz; Ziółkowski, Adam; Bieńkowska, Barbara; Prokopowicz, Rafał; Łaszyńska, Ewa; Kowalska-Strzeciwilk, Ewa; Poźniak, Krzysztof T.; Kasprowicz, Grzegorz; Zabołotny, Wojciech; Wojeński, Andrzej; Krawczyk, Rafał D.; Linczuk, Paweł; Potrykus, Paweł; Bajdel, Barcel

    2016-09-01

    One of the requests from the ongoing ITER-Like Wall Project is to have diagnostics for Soft X-Ray (SXR) monitoring in tokamak. Such diagnostics should be focused on tungsten emission measurements, as an increased attention is currently paid to tungsten due to a fact that it became a main candidate for the plasma facing material in ITER and future fusion reactor. In addition, such diagnostics should be able to withstand harsh radiation environment at tokamak during its operation. The presented work is related to the development of such diagnostics based on Gas Electron Multiplier (GEM) technology. More specifically, an influence of neutron radiation on performance of the GEM detectors is studied both experimentally and through computer simulations. The neutron induced radioactivity (after neutron source exposure) was found to be not pronounced comparing to an impact of other secondary neutron reaction products (during the exposure).

  5. The gas electron multiplier (GEM): Operating principles and applications

    Science.gov (United States)

    Sauli, Fabio

    2016-01-01

    Introduced by the author in 1997, The Gas Electron Multiplier (GEM) constitutes a powerful addition to the family of fast radiation detectors; originally developed for particle physics experiments, the device and has spawned a large number of developments and applications; a web search yields more than 400 articles on the subject. This note is an attempt to summarize the status of the design, developments and applications of the new detector.

  6. Algorithm for fast event parameters estimation on GEM acquired data

    Science.gov (United States)

    Linczuk, Paweł; Krawczyk, Rafał D.; Poźniak, Krzysztof T.; Kasprowicz, Grzegorz; Wojeński, Andrzej; Chernyshova, Maryna; Czarski, Tomasz

    2016-09-01

    We present study of a software-hardware environment for developing fast computation with high throughput and low latency methods, which can be used as back-end in High Energy Physics (HEP) and other High Performance Computing (HPC) systems, based on high amount of input from electronic sensor based front-end. There is a parallelization possibilities discussion and testing on Intel HPC solutions with consideration of applications with Gas Electron Multiplier (GEM) measurement systems presented in this paper.

  7. Radiation monitoring of the GEM muon detectors at CMS

    Science.gov (United States)

    Dimitrov, L.; Iaydjiev, P.; Mitev, G.; Vankov, I.

    2016-09-01

    The higher energy and luminosity of future High Luminosity (HL) LHC, determines a significant increasing of the radiation background around the CMS subdetectors, and especially in the higher pseudorapidity region. Under such heavy conditions, the RPC (used in muon trigger) most probably could not operate effectively. GEM (Gas Electron Multiplier) detectors have been identified as a suitable technology to operate in the high radiation environment in that region and test at CMS will start in 2016. A monitoring system to control the absorbed radiation dose by the GEM under test is developed. Two types of sensors are used in it: RadFETs for total absorbed dose and p-i-n diodes for particle (proton and neutron) detection. The basic detector unit, called RADMON, contains two sensors of each type and can be installed at each GEM detector. The system has a modular structure, permitting to increase easily the number of controlled RADMONs: one module controls up to 12 RADMONs, organized in three group of four and communicates outside by RS 485 and CANBUS interfaces.

  8. Fast readout of GEM detectors for medical imaging

    Energy Technology Data Exchange (ETDEWEB)

    Bucciantonio, M., E-mail: martina.bucciantonio@cern.ch [Tera Foundation, Novara (Italy); Albert Einstein Center for Fundamental Physics, Laboratory for High Energy Physics, University of Bern, Bern (Switzerland); Amaldi, U.; Kieffer, R.; Malakhov, N.; Sauli, F.; Watts, D. [Tera Foundation, Novara (Italy)

    2013-08-01

    We describe the design and implementation of a fast data acquisition (DAQ) system for Gas Electron Multiplier (GEM) trackers applied to imaging and dosimetry in hadrontherapy. Within the AQUA project of the TERA foundation a prototype of Proton Range Radiography of 30×30 cm{sup 2} active area has been designed and built to provide in-beam integrated density images of the patient before treatment. It makes use of a pair of GEMs to record position and direction of protons emerging from the target. A fast data acquisition rate close to 1 MHz will allow obtaining a good resolution in-beam proton radiography in a few seconds. A dedicated fast front-end circuit for GEM detectors (GEMROC by AGH-Crakow University) is read by the FPGA based DAQ card (GR{sub D}AQ), developed by the AQUA group. The same system is under evaluation (within the ENVISION European project) to realize the in-vivo dosimetry, based on detecting secondary light particles during the treatment of the patient.

  9. Fast readout of GEM detectors for medical imaging

    Science.gov (United States)

    Bucciantonio, M.; Amaldi, U.; Kieffer, R.; Malakhov, N.; Sauli, F.; Watts, D.

    2013-08-01

    We describe the design and implementation of a fast data acquisition (DAQ) system for Gas Electron Multiplier (GEM) trackers applied to imaging and dosimetry in hadrontherapy. Within the AQUA project of the TERA foundation a prototype of Proton Range Radiography of 30×30 cm2 active area has been designed and built to provide in-beam integrated density images of the patient before treatment. It makes use of a pair of GEMs to record position and direction of protons emerging from the target. A fast data acquisition rate close to 1 MHz will allow obtaining a good resolution in-beam proton radiography in a few seconds. A dedicated fast front-end circuit for GEM detectors (GEMROC by AGH-Crakow University) is read by the FPGA based DAQ card (GR_DAQ), developed by the AQUA group. The same system is under evaluation (within the ENVISION European project) to realize the in-vivo dosimetry, based on detecting secondary light particles during the treatment of the patient.

  10. A Study of a Mini-drift GEM Tracking Detector

    CERN Document Server

    Azmoun, B; Franz, A; Kiselev, A; Pak, R; Phipps, M; Purschke, M L; Woody, C

    2015-01-01

    A GEM tracking detector with an extended drift region has been studied as part of an effort to develop new tracking detectors for future experiments at RHIC and for the Electron Ion Collider that is being planned for BNL or JLAB. The detector consists of a triple GEM stack with a small drift region that was operated in a mini TPC type configuration. Both the position and arrival time of the charge deposited in the drift region were measured on the readout plane which allowed the reconstruction of a short vector for the track traversing the chamber. The resulting position and angle information from the vector could then be used to improve the position resolution of the detector for larger angle tracks, which deteriorates rapidly with increasing angle for conventional GEM tracking detectors using only charge centroid information. Two types of readout planes were studied. One was a COMPASS style readout plane with 400 micron pitch XY strips and the other consisted of 2x10mm2 chevron pads. The detector was studie...

  11. GEMS: a mobile wireless network for atmospheric sampling

    Science.gov (United States)

    Adams, Mark L.; Manobianco, John; Bickford, James

    2005-06-01

    Large scale, mobile ad-hoc networks (MANET) are of great interest for a number of applications including battlesphere dominance and homeland security. ENSCO, Inc. is designing a system for profiling large regions of the atmosphere. The concept, known as Global Environmental Micro Sensors (GEMS), features an integrated system of airborne probes that will remain suspended in the atmosphere and take measurements of pressure, temperature, humidity, and wind velocity as they are carried by atmospheric currents. In addition to gathering meteorological data, the probes could be used for monitoring and predicting the dispersion of particulate emissions, organic and inorganic pollutants, ozone, carbon dioxide, and chemical, biological, or nuclear contaminants. Several functionality requirements are called into question when investigating a scalable mobile network protocol. For instance, periodic reporting may not always be required and can be abandoned in favor of event-driven reports. Similarly, network connectivity may not be required at all times. Instead of constant global connectivity, paths can be formed only when data packets are ready for transmission. For a successful GEMS system, the most important network function is to relay timely data to one or more receiving stations. We will present both the GEMS system and probe design as well as discuss the trade-offs associated with optimizing a three-dimensional, mobile, airborne network comprised of low-cost, low-power probes. We will also analyze and present measured data to determine the performance of a representative MANET under actual environmental conditions and various aspects of mobility.

  12. MIT App Inventor: Enabling Personal Mobile Computing

    OpenAIRE

    Pokress, Shaileen Crawford; Veiga, José Juan Dominguez

    2013-01-01

    MIT App Inventor is a drag-and-drop visual programming tool for designing and building fully functional mobile apps for Android. App Inventor promotes a new era of personal mobile computing in which people are empowered to design, create, and use personally meaningful mobile technology solutions for their daily lives, in endlessly unique situations. App Inventor's intuitive programming metaphor and incremental development capabilities allow the developer to focus on the logic for programming ...

  13. Integrierte Produktions- und Distributionsplanung mit Routingentscheidungen

    OpenAIRE

    Wendt, Rolf

    2016-01-01

    Die zentrale Problemstellung dieser Arbeit entstammt dem operationellen Supply Chain Management. Es liegen Bestellungen von Kunden vor, für die jeweils zu entscheiden ist, ob sie angenommen werden sollen. Die angenommenen Bestellungen sind auf einem vorhandenen Maschinenpark zu produzieren und fertiggestellte Bestellungen sind an den jeweiligen Kunden auszuliefern. Zu diesem Zwecke steht eine Transporterflotte bereit, wobei die Auslieferung in der Form "Sammelauslieferung mit Rundreise" erfol...

  14. Grundlegende Steuerungsverfahren im heterogenen Logistiknetz mit Kanban

    Science.gov (United States)

    Dickmann, Eva; Dickmann, Philipp; Lödding, Hermann; Möller, Niklas; Rücker, Thomas; Schneider, Herfried M.; Zäh, Michael F.

    In vielen Unternehmen werden heterogene (verschiedene) Steuerungen in einem abgestimmten Konzept kombiniert. Je nach Anwendungsfall und Rahmenbedingungen werden Kombinationen allgemein bekannter Steuerungen oder Steuerungsvarianten gemischt eingesetzt, um eine optimale Steuerung für unterschiedliche Fälle zu erreichen. Hierbei stehen neben den bekannten und weit verbreiteten Methoden, wie Material Requirements Planning (MRP) oder Kanban, auch weniger bekannte oder neue Methoden zur Auswahl, wie die Produktionssteuerung mit dezentraler, bestandsorientierter Fertigungsregelung (DBF). Kanban ist ein simples und effizientes Steuerungskonzept, das in der klassischen Form für spezifische einfache Anwendungsfälle umsetzbar ist. Hochentwickelte Steuerungsalgorithmen können helfen, komplexe Abläufe optimal abzubilden. Mit einer grundlegenden Vereinfachung der Abläufe kann allerdings in vielen Fällen ein wesentlich stärkerer und umfassender Verbesserungseffekt erzielt werden. Die wesentliche Fragestellung sollte folglich lauten: Warum ist der Ablauf nicht mit einer einfachen Steuerung wie Kanban abzubilden? Um die Vorteile des Konzepts auch in untypischen Bereichen anwenden zu können, sind jedoch verschiedene Varianten oder Kanban-ähnliche Steuerungsmethoden entstanden. Darüber hinaus sind in der Praxis hybride Steuerungen im Einsatz, welche so kombiniert werden, dass die Zusammensetzung anspruchsvolle Eigenschaftsbilder noch exakt abbildet. In der Praxis basieren die Steuerungsentscheidungen nur zu einem kleinen Teil auf den eigentlichen Steuerungsalgorithmen, wie sie uns das MRP-System zur Verfügung stellt. Moderne Steuerungswelten" schließen alle relevanten Informationsquellen in eine heterogene Entscheidungsmatrix mit ein. Letztlich zählt nicht, ob die Entscheidung auf den Informationen aus dem MRP-System oder auf Softfacts basierend getroffen wurde, sondern nur, ob die Entscheidung erfolgreich war.

  15. Synthesis and Biological Evaluation of Glycosidase Inhibitors: gem-Difluoromethylenated Nojirimycin Analogues

    DEFF Research Database (Denmark)

    Bols, Mikael; Wang, Ruo-Wen; Qiu, Xiao-Long;

    2006-01-01

    In our ongoing program aimed at the design, synthesis, and biological evaluation of novel gem-difluoromethylenated glycosidase inhibitors, gem-4,4-difluoromethylenated iminosugars (5-9) were synthesized. The biological evaluation of these synthetic iminosugars showed that the gem-difluoromethylen......In our ongoing program aimed at the design, synthesis, and biological evaluation of novel gem-difluoromethylenated glycosidase inhibitors, gem-4,4-difluoromethylenated iminosugars (5-9) were synthesized. The biological evaluation of these synthetic iminosugars showed that the gem....... It is proposed that the unprotonated iminosugar is the species preferably bound by beta-glucosidase, due to the lower pK(a) value of iminosugar 6 than of 1 or 36, leaving iminosugars 1 and 36 mostly protonated at pH 5.0, while iminosugar 6 is not. Iminosugar 6 also displayed good and selective inhibition of beta...

  16. Improvement in the geopotential derived from satellite and surface data (GEM 7 and 8)

    Science.gov (United States)

    Wagner, C. A.; Lerch, F. J.; Brownd, J. E.; Richardson, J. A.

    1976-01-01

    A refinement was obtained in the earth's gravitational field using satellite and surface data. In addition to a more complete treatment of data previously employed on 27 satellites, the new satellite solution (Goddard Earth Model 7) includes 64,000 laser measurements taken on 7 satellites during the international satellite geodesy experiment (ISAGEX) program. The GEM 7, containing 400 harmonic terms, is complete through degree and order 16. The companion solution GEM 8 combines the same satellite data as in GEM 7 with surface gravimetry over 39% of the earth. The GEM 8 is complete to degree and order 25. Extensive tests on data independent of the solution show that the undulation of the geoidal surface computed by GEM 7 has an accuracy of about 3m (rms). The overall accuracy of the geoid estimated by GEM 8 is estimated to be about 4-1/4m (rms), an improvement of almost 1m over previous solutions.

  17. On the efficient operation of a CsI-coated GEM photon detector

    CERN Document Server

    Mörmann, D; Chechik, R; Singh, B K

    2001-01-01

    We report on the efficient operation of a CsI-coated GEM photon detector. We describe its operation mode and the dependence of the single electron detection efficiency on the electric fields. Conditions for obtaining full efficiency of photoelectron extraction and their focusing into the GEM apertures, in 1 atm CH sub 4 , are presented. The quantum efficiency of the CsI-coated GEM is 35% at 150 nm.

  18. Evaluation of ozone profile and tropospheric ozone retrievals from GEMS and OMI spectra

    Directory of Open Access Journals (Sweden)

    J. Bak

    2012-09-01

    Full Text Available Korea is planning to launch the GEMS (Geostationary Environment Monitoring Spectrometer instrument into a Geostationary (GEO platform in 2018 to monitor tropospheric air pollutants on an hourly basis over East Asia. GEMS will measure backscattered UV radiances covering the 300–500 nm wavelength range with a spectral resolution of 0.6 nm. The main objective of this study is to evaluate ozone profiles and stratospheric column ozone amounts retrieved from simulated GEMS measurements. Ozone Monitoring Instrument (OMI Level 1B radiances, which have the spectral range 270–500 nm at spectral resolution of 0.42–0.63 nm, are used to simulate the GEMS radiances. An optimal estimation-based ozone profile algorithm is used to retrieve ozone profiles from simulated GEMS radiances. Firstly, we compare the retrieval characteristics (including averaging kernels, degrees of freedom for signal, and retrieval error derived from the 270–330 nm (OMI and 300–330 nm (GEMS wavelength ranges. This comparison shows that the effect of not using measurements below 300 nm on tropospheric ozone retrievals is insignificant. However, the stratospheric ozone information decreases greatly from OMI to GEMS, by a factor of ∼2. The number of the independent pieces of information available from GEMS measurements is estimated to 3 on average in the stratosphere, with associated retrieval errors of ∼1% in stratospheric column ozone. The difference between OMI and GEMS retrieval characteristics is apparent for retrieving ozone layers above ∼20 km, with a reduction in the sensitivity and an increase in the retrieval errors for GEMS. We further investigate whether GEMS can resolve the stratospheric ozone variation observed from high vertical resolution EOS Microwave Limb Sounder (MLS. The differences in stratospheric ozone profiles between GEMS and MLS are comparable to those between OMI and MLS above ∼3 hPa (∼40 km except with slightly larger biases and larger

  19. MIT - Mighty Steps toward Energy Sustainability

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Alastair [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Regnier, Cindy [Lawrence Berkeley National Lab. (LBNL), Berkeley, CA (United States); Settlemyre, Kevin [Sustainable IQ, Inc., Arlington, MA (United States); Bosnic, Zorana [HOK, San Francisco, CA (United States)

    2012-07-01

    Massachusetts Institute of Technology (MIT) partnered with the U.S. Department of Energy (DOE) to develop and implement solutions to retrofit existing buildings to reduce energy consumption by at least 30% as part of DOE’s Commercial Building Partnerships (CBP) Program.1 Lawrence Berkeley National Laboratory (LBNL) provided technical expertise in support of this DOE program. MIT is one of the U.S.’s foremost higher education institutions, occupying a campus that is nearly 100 years old, with a building floor area totaling more than 12 million square feet. The CBP project focused on improving the energy performance of two campus buildings, the Ray and Maria Stata Center (RMSC) and the Building W91 (BW91) data center. A key goal of the project was to identify energy saving measures that could be applied to other buildings both within MIT’s portfolio and at other higher education institutions. The CBP retrofits at MIT are projected to reduce energy consumption by approximately 48%, including a reduction of around 72% in RMSC lighting energy and a reduction of approximately 55% in RMSC server room HVAC energy. The energy efficiency measure (EEM) package proposed for the BW91 data center is expected to reduce heating, ventilation, and air-conditioning (HVAC) energy use by 30% to 50%, depending on the final air intake temperature that is established for the server racks. The RMSC, an iconic building designed by Frank Gehry, houses the Computer Science and Artificial Intelligence Laboratory, the Laboratory for Information and Decision Systems, and the Department of Linguistics and Philosophy.

  20. [Bernt Ahrenholz : Verweise mit Demonstrativa im Gesprochenen Deutsch...] / Klaus Geyer

    Index Scriptorium Estoniae

    Geyer, Klaus

    2008-01-01

    Arvustus: Ahrenholz, Bernt. Verweise mit Demonstrativa im gesprochenen Deutsch : Grammatik, Zweitspracherwerb und Deutsch als Fremdsprache. Berlin ; New York : de Gruyter, 2007. (Linguistik - Impulse & Tendenzen ; 17)

  1. A Time Projection Chamber with GEM-Based Readout

    CERN Document Server

    Attié, David; Bellerive, Alain; Bezshyyko, Oleg; Bhattacharya, Deb Sankar; Bhattacharya, Purba; Bhattacharya, Sudeb; Caiazza, Stefano; Colas, Paul; De Lentdecker, Gilles; Dehmelt, Klaus; Desch, Klaus; Diener, Ralf; Dixit, Madhu; Fleck, Ivor; Fujii, Keisuke; Fusayasu, Takahiro; Ganjour, Serguei; Gao, Yuanning; Gros, Philippe; Hayman, Peter; Hedberg, Vincent; Ikematsu, Katsumasa; Jönsson, Leif; Kaminski, Jochen; Kato, Yukihiro; Kawada, Shin-ichi; Killenberg, Martin; Kleinwort, Claus; Kobayashi, Makoto; Krylov, Vladyslav; Li, Bo; Li, Yulan; Lundberg, Björn; Lupberger, Michael; Majumdar, Nayana; Matsuda, Takeshi; Mehdiyev, Rashid; Mjörnmark, Ulf; Müller, Felix; Münnich, Astrid; Mukhopadhyay, Supratik; Ogawa, Tomohisa; Oskarsson, Anders; Österman, Lennart; Peterson, Daniel; Riallot, Marc; Rosemann, Christoph; Roth, Stefan; Schade, Peter; Schäfer, Oliver; Settles, Ronald Dean; Shirazi, Amir Noori; Smirnova, Oxana; Sugiyama, Akira; Takahashi, Tohru; Tian, Junping; Timmermans, Jan; Titov, Maksym; Tsionou, Dimitra; Vauth, Annika; Wang, Wenxin; Watanabe, Takashi; Werthenbach, Ulrich; Yang, Yifan; Yang, Zhenwei; Yonamine, Ryo; Zenker, Klaus; Zhang, Fan

    2016-01-01

    For the International Large Detector concept at the planned International Linear Collider, the use of time projection chambers (TPC) with micro-pattern gas detector readout as the main tracking detector is investigated. In this paper, results from a prototype TPC, placed in a 1 T solenoidal field and read out with three independent GEM-based readout modules, are reported. The TPC was exposed to a 6 GeV electron beam at the DESY II synchrotron. The efficiency for reconstructing hits, the measurement of the drift velocity, the space point resolution and the control of field inhomogeneities are presented.

  2. GEMS: Underwater spectrometer for long-term radioactivity measurements

    OpenAIRE

    2010-01-01

    GEMS (Gamma Energy Marine Spectrometer) is a prototype of an autonomous radioactivity sensor for underwater measurements, developed in the framework of the KM3NeT Design Study (DS) EC project. The spectrometer is sensitive to gamma rays produced by 40K decays and it is also able to detect other natural (e.g., 238U, 232Th) and anthropogenic radionuclides (e.g. 137Cs). The decay of 40K, contained in sea salt, particulate and sediments, is one of the main sources of photon background...

  3. Electron transmission efficiency of gating-GEM foil for TPC

    Institute of Scientific and Technical Information of China (English)

    XIE Wen-Qing; HUANG Meng; LI Ting; TIAN Yang; LI Yu-Lan; LI Yuan-Jing

    2012-01-01

    In a TPC,ion feedback from the readout detector can cause a space-charge effect and distort the electrical field in the drift region.Gating is one of the effective methods to solve this problem,which can block ions at the expense of losing a certain amount of primary electrons.Compared with the traditional design with a wire structure,gating based on GEM foil is more attractive because of its simplicity.In this paper,the factors influencing the electron transmission efficiency are studied with simulations and experiments.After optimizing all these parameters,an electron transmission efficiency over 80% is obtained.

  4. Simulation of the GEM silicon central tracker using GEANT

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, M.L.; Kinnison, W.W.

    1994-01-01

    The silicon central tracker of the GEM detector has been simulated using the high energy physics simulations code GEANT. This paper will describe the level of detail of the geometry of the tracker that is in the code, including the silicon detectors themselves as well as all non-sensitive volumes such as support structures; the digitization, or detector response to particles, of the silicon detectors; the coordinate reconstruction from the digitizations, and some of the results of the simulations regarding the detector performance.

  5. Life with quintuplets: transitioning GeMS into regular operations

    Science.gov (United States)

    Garrel, Vincent; Van Dam, Marcos A.; Neichel, Benoît; Vidal, Fabrice; Sivo, Gaetano; Marin, Eduardo; Montes, Vanessa; Serio, Andrew; Arriagada, Gustavo; Trujillo, Chadwick; Rambold, William N.; Gigoux, Pedro; Galvez, Ramon; Moreno, Cristian; Araujo Hauck, Constanza; Vucina Parga, Tomislav; Donahue, Jeff; Marchant, Claudio; Gausachs, Gaston; Collao, Fabian; Carrasco Damele, Eleazar R.; Pessev, Peter; Lopez, Ariel

    2014-08-01

    The Gemini Multi-conjugate adaptive optics System (GeMS) at the Gemini South telescope in Cerro Pachon is the first sodium Laser Guide Star (LGS) adaptive optics (AO) system with multiple guide stars. It uses five LGSs and two deformable mirrors (DMs) to measure and compensate for distortions induced by atmospheric turbulence. After its 2012 commissioning phase, it is now transitioning into regular operations. Although GeMS has unique scientific capabilities, it remains a challenging instrument to maintain, operate and upgrade. In this paper, we summarize the latest news and results. First, we describe the engineering work done this past year, mostly during our last instrument shutdown in 2013 austral winter, covering many subsystems: an erroneous reconjugation of the Laser guide star wavefront sensor, the correction of focus field distortion for the natural guide star wavefront sensor and engineering changes dealing with our laser and its beam transfer optics. We also describe our revamped software, developed to integrate the instrument into the Gemini operational model, and the new optimization procedures aiming to reduce GeMS time overheads. Significant software improvements were achieved on the acquisition of natural guide stars by our natural guide star wavefront sensor, on the automation of tip-tilt and higher-order loop optimization, and on the tomographic non-common path aberration compensation. We then go through the current operational scheme and present the plan for the next years. We offered 38 nights in our last semester. We review the current system efficiency in term of raw performance, completed programs and time overheads. We also present our current efforts to merge GeMS into the Gemini base facility project, where night operations are all reliably driven from our La Serena headquarter, without the need for any spotter. Finally we present the plan for the future upgrades, mostly dedicated toward improving the performance and reliability of the

  6. Long-term stability test of a triple GEM detector

    CERN Document Server

    Adak, R P; Das, S; Ghosal, D; Ghosh, S K; Mondal, A; Nag, D; Nayak, T K; Patra, R N; Prasad, S K; Raha, S; Sahu, P K; Sahu, S; Swain, S

    2016-01-01

    The main aim of the study is to perform the long-term stability test of gain of the single mask triple GEM detector. A simple method is used for this long- term stability test using a radioactive X-ray source with high activity. The test is continued till accumulation of charge per unit area > 12.0 mC/mm2. The details of the chamber fabrication, the test set-up, the method of measurement and the test results are presented in this paper.

  7. Copper-Catalyzed SN2'-Selective Allylic Substitution Reaction of gem-Diborylalkanes.

    Science.gov (United States)

    Zhang, Zhen-Qi; Zhang, Ben; Lu, Xi; Liu, Jing-Hui; Lu, Xiao-Yu; Xiao, Bin; Fu, Yao

    2016-03-04

    A Cu/(NHC)-catalyzed SN2'-selective substitution reaction of allylic electrophiles with gem-diborylalkanes is reported. Different substituted gem-diborylalkanes and allylic electrophiles can be employed in this reaction, and various synthetic valuable functional groups can be tolerated. The asymmetric version of this reaction was initially researched with chiral N-heterocyclic carbene (NHC) ligands.

  8. Gem Detectors For the Transverse Profile Measurement of Low Energy Antiprotons and High Energy Hadrons

    CERN Document Server

    Spanggaard, J; Duarte Pinto, S; Tranquille, G

    2013-01-01

    Gas Electron Multipliers (GEM) are finding more and more applications in beam instrumentation. Gas Electron Multiplication is a very similar physical phenomenon to that which occurs in Multi Wire Proportional Chambers (MWPC), but for small profile monitors GEMs are much more cost effective to produce and maintain. \

  9. A scintillating GEM for 2D-dosimetry in radiation therapy

    NARCIS (Netherlands)

    Timmer, JH; van Vuure, TL; Bom, [No Value; van Eijk, CW; de Haas, J; Schippers, JM

    2002-01-01

    The first results of a study on the properties of a gaseous scintillation detector based on a Gas Electron Multiplier (GEM) are reported. The detector is designed for use in position-sensitive dosimetry applications in radiation therapy. A double GEM system, operating in a 90 10% Ar-CO2 gas mixture

  10. Investigations on Important Properties of the 10 cm x 10 cm GEM Prototype

    CERN Document Server

    Saenboonruang, Kiadtisak; Kulasri, Kittipong; Ritthirong, Anawat

    2015-01-01

    The Gas Electron Multiplier (GEM) detector is one of promising particle and radiation detectors that has been improved greatly from previous gas detectors. The improvement includes better spatial resolutions, higher detection rate capabilities, and flexibilities in designs. In particular, the 10 cm x 10 cm GEM prototype is designed and provided by the Gas Detectors Development group (GDD) at CERN, Switzerland. With its simplicity in operations and designs, while still maintaining high qualities, the GEM prototype is suitable for both start-up and advanced researches. This article aims to report the investigations on some important properties of the 10 cm x 10 cm GEM detector using current measurement and signal counting. Results have shown that gains of the GEM prototype exponentially increase as voltage supplied to the detector increases, while the detector reaches full efficiency (plateau region) when the voltage is greater than 4100 V. In terms of signal sharing between X and Y strips of the readout, X str...

  11. Formation of GEMS from shock-accelerated crystalline dust in superbubbles

    CERN Document Server

    Westphal, A J

    2004-01-01

    Interplanetary dust particles (IDPs) contain enigmatic sub-micron components called GEMS (Glass with Embedded Metal and Sulfides). The compositions and structures of GEMS indicate that they have been processed by exposure to ion- izing radiation but details of the actual irradiation environment(s) have remained elusive. Here we propose a mechanism and astrophysical site for GEMS formation that explains for the first time the following key properties of GEMS; they are stoichiometrically enriched in oxygen and systematically deple- ted in S, Mg, Ca and Fe (relative to solar abundances), most have normal (solar) oxygen isotopic compositions, they exhibit a strikingly narrow size distribution (0.1-0.5 $\\mu$m diameter), and some of them contain ``relict'' crystals within their glass matrices. We show that these properties are incon- sistent with amorphization by particles accelerated by diffusive shock accel- eration. Instead, we propose that GEMS are formed from crystalline grains that condense in outflows from m...

  12. Characterization of GEM foils and materials simulation, measurements and interferometric monitoring tools

    CERN Document Server

    Benussi, Luigi

    2015-01-01

    The GE1/1 CMS project consists of 144 GEM chambers of about 0.5 qm active area each, based on the triple GEMs technology, to be installed in the very forward region of the CMS endcap during the long shutdown of LHC in 2108-2019. GE1/1 chambers will be operated for decades in harsh environment, and are expected to perform consistently providing good space and time resolution and excellent rate capabilities. An extensive material science simulation and measurement campaign is in progress to characterize GEM materials, with main focus on the GEM foils. Results are presented on full Finite Element Analysis simulations, measurement of tensile properties and humidity absorption coefficients, both for unused and irradiated samples. Preliminary results are shown on interferometric methods based on Moirè fringes for the monitoring of GEM foils mechanical properties during chamber construction.

  13. Investigation of GEM-Micromegas Detector on X-ray Beam of Synchrotron Radiation

    CERN Document Server

    Zhang, YuLian; Hu, BiTao; Fan, ShengNan; Wang, Bo; Liu, Mei; Zhang, Jian; Liu, RongGuang; Chang, GuangCai; Liu, Peng; Ouyang, Qun; Chen, YuanBo; Yi, FuTing

    2013-01-01

    To solve the discharge of the standard Bulk Micromegas and GEM detector, the GEM-Micromegas detector was developed in Institute of High Energy Physics. Taking into account the advantages of the two detectors, one GEM foil was set as a preamplifier on the mesh of Micromegas in the structure and the GEM preamplification decreased the working voltage of Micromegas to reduce the effect of the discharge significantly. In the paper, the performance of detector in X-ray beam was studied at 1W2B laboratory of Beijing Synchrotron Radiation Facility. Finally, the result of the energy resolution under various X-ray energies was given in different working gases. It indicated that the GEM-Micromegas detector had the energy response capability in all the energy range and it could work better than the standard Bulk-Micromegas.

  14. Great Explorations in Math and Science[R] (GEMS[R]) Space Science. What Works Clearinghouse Intervention Report

    Science.gov (United States)

    What Works Clearinghouse, 2012

    2012-01-01

    "Great Explorations in Math and Science[R] (GEMS[R]) Space Science" is an instructional sequence for grades 3-5 that covers fundamental concepts, including planetary sizes and distance, the Earth's shape and movement, gravity, and moon phases and eclipses. Part of the "GEMS"[R] core curriculum, "GEMS[R] Space Science"…

  15. PREFACE: Science's gem: diamond science 2009 Science's gem: diamond science 2009

    Science.gov (United States)

    Mainwood, Alison; Newton, Mark E.; Stoneham, Marshall

    2009-09-01

    Natural diamond has been valued for its appearance and mechanical properties for at least two thousand years. As a gem stone diamond is unsurpassed. However, scientific work, especially in the last 20 years, has demonstrated that diamond has numerous surprising properties and many unique ones. Some of the extreme properties have been known for many years, but the true scale of diamond's other highly desirable features is still only coming to light as control in the synthesis of diamond, and hence material perfection, improves. The ultimate prize for man-made diamond is surely not in the synthesis of gem stones, but in delivering technological solutions enabled by diamond to the challenges facing our society today. If the special properties are to be exploited to their full potential, at least four crucial factors must be considered. First, there must be sufficient scientific understanding of diamond to make applications effective, efficient and economical. Secondly, the means of fabrication and control of properties have to be achieved so that diamond's role can be optimised. Thirdly, it is not enough that its properties are superior to existing materials: they must be so much better that it is worth initiating new technologies to exploit them. Finally, any substantial applications will have to address the society's major needs worldwide. The clear technology drivers for the 21st century come from the biomedical technologies, the demand for energy subject to global constraints, and the information technologies, where perhaps diamond will provide the major enabling technology [1]. The papers in this volume concern the solid state physics of diamond, and primarily concern the first two factors: understanding, and control of properties. They address many of the outstanding basic problems, such as the identification of existing defects, which affect the material's properties, both desirable and less so. Regarding future substantial applications, one paper discusses

  16. Two-dimensional position sensitive ionization chamber with GEM

    Science.gov (United States)

    Kitamura, Noritaka; Noro, Tetsuo; Sakaguchi, Satoshi; Takao, Hideaki; Nishio, Yasutaka

    2014-09-01

    We have been developing a multi-anode ionization chamber for Accelerator Mass Spectrometry (AMS) at Kyushu University. Furthermore, we are planning to construct a neutron detector with high position resolution by combining the chamber with Gas Electron Multiplier (GEM) and a neutron converter. One of purposes is the measurement of p-> , pn knockout reaction from unstable nuclei. The multi-anode ionization chamber is composed of subdivided multiple anodes, a cathode to produce an uniform electric field, and a Frisch grid. The chamber must have position sensitivity because obtaining a beam profile is required for AMS measurements, where counting loss should be avoided. Also in the case of the neutron detector, it is necessary to measure the position to deduce the scattering angles. We have recently established a two-dimensional position readout system by the following methods: the measurement of horizontal position is enabled by trimming some anodes into wedge-like shape, and vertical position can be determined by the ratio of induced charge on the grid to the total charge on anodes. In addition, improvement of S/N ratio is important for isotope separation and position resolution. We installed a rectangular-shaped GEM and tried improving S/N ratio by electron amplification.

  17. E-GEM- European GNSS-R Environmental Monitoring

    Science.gov (United States)

    Catarino, Nuno; Bandeiras, Jorge; Peres, Tiago; Silva, Pedro; Camps, Adriano; Carreno, Hugo; Cardellach, Estel; Capron, Bertrand; Fohannessen, Johnny; Danielson, Rick; Guerriero, Leila; Pierdicca, Nazzareno; Sanchez, Nilda; Storvold, Rune; Wickert, Jens

    2016-08-01

    Earth Monitoring with GNSS signals is a promising novel area for Earth Observations systems. The increasing number of sources, together with the low level of requirements (power, size, budget, etc.) and possibility of using COTS hardware, makes these systems potentially very attractive for future space missions, making this a very attractive complementary technology to traditional active radar systems. Since the use of reflected GNSS signals was proposed in 1993, the number of research activities and scientific publications has been steadily increasing, especially in recent years, where the attention devoted to GNSS-R has increased exponentially after NASA has approved the first operational use of GNSS-R from space, the eight-satellite CYGNSS constellation.The European GNSS-R Earth Monitoring project (E- GEM, www.e-gem.eu), started in 2014, is an FP7 funded project which joins many of the European experts in the field of GNSS-R and involves ten of the top European institutions in this field. The goal of this project is quite ambitions, covering both instruments and scientific algorithms developments of for a number of applications.

  18. The stable K0 giant star β Gem

    Energy Technology Data Exchange (ETDEWEB)

    Gray, David F., E-mail: dfgray@uwo.ca [Department of Physics and Astronomy, University of Western Ontario, 1151 Richmond Street, London, Ontario, N6A 3K7 (Canada)

    2014-12-01

    A nine-season spectroscopic study of the photosphere of β Gem (K0 III) shows this low-luminosity giant to be stable, with no effective temperature variations above ∼2 K, and no secular temperature variations over the 2002-2010 time span above 0.2 K per year. The radial-velocity variations are consistent with an orbital variation of ∼40 m s{sup –1}. The projected rotation rate is found to be 1.70 ± 0.20 km s{sup –1} with a macroturbulence dispersion of 4.53 ± 0.10 km s{sup –1}. The third-signature plot is also invariant and shows a granulation velocity gradient 20% smaller than the solar gradient. The absolute shift of the third-signature plot gives a blueshift-corrected radial velocity of 3385 ± 70 m s{sup –1}. Bisector mapping of the Fe I λ6253 line yields a flux deficit of 12% ± 1% in area, somewhat smaller than for other giants, but the shape and the position of the peak at 4.8 km s{sup –1} is consistent with other giants. All of the investigated photospheric parameters are consistent with β Gem being a low-luminosity giant in agreement with its absolute magnitude.

  19. Dentinhaftung von Zementen. Der Haftverbund von Zementen mit Dentin in Kombination mit verschiedenen indirekten Restaurationsmaterialien

    OpenAIRE

    Peutzfeldt, Anne; Sahafi, Alireza; Flury, Simon

    2011-01-01

    Einleitung: Die Anzahl zahnärztlicher Zemente sowie Restaurationsmaterialien steigt stetig. Die richtige Zementwahl für einen zuverlässigen Haftverbund zwischen Restaurationsmaterial und Zahnsubstanz ist von Interesse für den Kliniker. Ziel der vorliegenden in vitro-Studie war es daher, den Dentinhaftverbund von verschiedenen Zementen in Kombination mit verschiedenen indirekten Restaurationsmaterialien zu untersuchen. Material und Methoden: Zylindrische Probekörper aus sechs Restaurations...

  20. Teaching ``The Physics of Energy'' at MIT

    Science.gov (United States)

    Jaffe, Robert

    2009-05-01

    New physics courses on energy are popping up at colleges and universities across the country. Many require little or no previous physics background, aiming to introduce a broad audience to this complex and critical problem, often augmenting the scientific message with economic and policy discussions. Others are advanced courses, focussing on highly specialized subjects like solar voltaics, nuclear physics, or thermal fluids, for example. About two years ago Washington Taylor and I undertook to develop a course on the ``Physics of Energy'' open to all MIT students who had taken MIT's common core of university level calculus, physics, and chemistry. By avoiding higher level prerequisites, we aimed to attract and make the subject relevant to students in the life sciences, economics, etc. --- as well as physical scientists and engineers --- who want to approach energy issues in a sophisticated and analytical fashion, exploiting their background in calculus, mechanics, and E & M, but without having to take advanced courses in thermodynamics, quantum mechanics, or nuclear physics beforehand. Our object was to interweave teaching the fundamental physics principles at the foundations of energy science with the applications of those principles to energy systems. We envisioned a course that would present the basics of statistical, quantum, and fluid mechanics at a fairly sophisticated level and apply those concepts to the study of energy sources, conversion, transport, losses, storage, conservation, and end use. In the end we developed almost all of the material for the course from scratch. The course debuted this past fall. I will describe what we learned and what general lessons our experience might have for others who contemplate teaching energy physics broadly to a technically sophisticated audience.

  1. Performance of GEM Detectors in the DarkLight Experiment at LERF

    Science.gov (United States)

    Mohammed Prem Nazeer, Sahara Jesmin; DarkLight Collaboration

    2017-01-01

    The DarkLight experiment has been proposed to search for a heavy photon A' in the mass range of 10-100 MeV/c2 produced in electron-proton collisions. Phase-I of DarkLight has started to take place in 2016 at the Low Energy Recirculator Facility (LERF) at Jefferson Lab. LERF delivered a 100 MeV electron beam onto a windowless hydrogen gas target. The phase-I detector tracks leptons inside the DarkLight solenoid with a set of Gas Electron Multiplier (GEM) detectors, combined with segmented scintillators for triggering. The GEM telescope consists of four 10 × 10 cm2 triple layer GEM chambers with 2D readout strips, mounted in a slightly angled fixed frame about 12 cm tall. The GEM data are read out with analog pipeline front-end cards (APV-25) each of which can process 128 readout channels. Each GEM chamber has 250 channels for each coordinate axis, read out with two APVs on each side, resulting in 2000 readout channels for the GEM stack, processed by 16 APVs. One Multi Purpose Digitizer (MPD) module is used to read out all of the 16 APV-25 cards. The current run status of DarkLight experiment and the performance of GEMs in the experiment will be discussed. This work has been supported by NSF PHY-1436680 and PHY-1505934.

  2. Geometrical model fitting for interferometric data: GEM-FIND

    CERN Document Server

    Klotz, D; Paladini, C; Hron, J; Wachter, G

    2012-01-01

    We developed the tool GEM-FIND that allows to constrain the morphology and brightness distribution of objects. The software fits geometrical models to spectrally dispersed interferometric visibility measurements in the N-band using the Levenberg-Marquardt minimization method. Each geometrical model describes the brightness distribution of the object in the Fourier space using a set of wavelength-independent and/or wavelength-dependent parameters. In this contribution we numerically analyze the stability of our nonlinear fitting approach by applying it to sets of synthetic visibilities with statistically applied errors, answering the following questions: How stable is the parameter determination with respect to (i) the number of uv-points, (ii) the distribution of points in the uv-plane, (iii) the noise level of the observations?

  3. Gem-quality Turkish purple jade: Geological and mineralogical characteristics

    Science.gov (United States)

    Hatipoğlu, Murat; Başevirgen, Yasemin; Chamberlain, Steven C.

    2012-02-01

    In the Harmancık-Bursa region of the western Anatolia (Turkey), an extensive contact metamorphic aureole at the border between the Late Mesozoic coherent metaclastic rocks of blueschist facies and the Early Senozoic intrusive granodiorite stock hosts an interesting and unique gem material with a mineral assemblage consisting mainly of jadeite, quartz, orthoclase, epidote, chloritoid, and phlogopite as identified by X-ray diffraction spectroscopy and polarized-light microscopy. In addition, chemical analyses performed with X-ray fluorescence and inductive-coupled plasma-atomic emission spectroscopy show that the mass of the metamorphic aureole has a silica-rich, calc-alkaline chemical content. Therefore, some rock building elements (such as Al, Ca, Na, K, P, Sr, and B of which characterize an acidic-neutral rock formation) and trace elements (such as Fe, Cr, Mn, Be, Cu, Ga, La, Ni, Pb, and Zn) are remarkable high ratios. Pale purple-colored gem material of this composition appears to be unique to Turkey, also is only found in one narrow provenance in Turkey. Therefore, it is specially called "Turkish (and/or Anatolian) purple jade" on the worldwide gem market. Even though the mineral jadeite is the principal constituent, 40% by volume as determined with petrographic thin-section examination under a polarized-light microscope, the material cannot be considered pure jadeite. Specific gravity measurements of the jade using a hydrostatic balance confirm that it has a heterogeneous structure. The measured average specific gravity of 3.04, is significantly lower than the normal range for characterized jadeites of 3.24-3.43. Turkish purple jade samples were examined in detail using dispersive confocal micro-Raman spectroscopy (DCμRS) as well as other well-known analytical methods. The resulting strong micro-Raman bands that peaked at 1038, 984, 697, 571, 521, 464, 430, 372, 326, 307, 264, and 201 cm -1 are characteristics of the Turkish purple jade. The first most

  4. Editorial: Reviewer selection process and new areas of expertise in GEMS

    Science.gov (United States)

    Liemohn, Michael W.; Balikhin, Michael; Kepko, Larry; Rodger, Alan; Wang, Yuming

    2016-06-01

    One method of selecting potential reviewers for papers submitted to the Journal of Geophysical Research Space Physics is to filter the user database within the Geophysical Electronic Manuscript System (GEMS) by areas of expertise. The list of these areas in GEMS can be self selected by users in their profile settings. The Editors have added 18 new entries to this list, an increase of 33% more than the previous 55 entries. All space physicists are strongly encouraged to update their profile settings in GEMS, especially their areas of expertise selections, and details of how to do this are provided.

  5. Characterization of a GEM-based fast neutron detector

    Energy Technology Data Exchange (ETDEWEB)

    Esposito, B., E-mail: basilio.esposito@enea.it [Associazione Euratom-ENEA sulla Fusione, Via E. Fermi, 45, I-00044 Frascati, Roma (Italy); Marocco, D.; Villari, R. [Associazione Euratom-ENEA sulla Fusione, Via E. Fermi, 45, I-00044 Frascati, Roma (Italy); Murtas, F. [Laboratori Nazionali di Frascati, Istituto Nazionale di Fisica Nucleare, Via E. Fermi, 40, I-00044 Frascati, Roma (Italy); Rodionov, R. [SRC RF TRINITI Troitsk, Moscow (Russian Federation)

    2014-03-21

    The neutron efficiency of a Gas Electron Multiplier (GEM)-based detector designed for fast neutron measurements in fusion devices was determined through the combined use of Monte Carlo (MCNPX) calculations and analysis of deuterium–deuterium and deuterium–tritium neutron irradiation experiments. The detector, characterized by a triple GEM structure flushed with a Ar/CO{sub 2}/CF{sub 4} – 45/15/40 gas mixture, features a digital read-out system and has two sub-units for the detection of 2.5+14 MeV neutrons and 14 MeV neutrons (U{sub DD} and U{sub DT}, respectively). The pulse height spectra (PHS) determined from the curves of experimental efficiency as a function of the detector's high voltage (HV) and the MCNPX-simulated PHS were compared using a fitting routine that finds the best match between the experimental and simulated PHS by assuming a parametric model for the relation between HV (that determines the detector's gain) and the energy deposited in the gas. This led to express the experimental neutron efficiency as a function of the discrimination level set on the deposited energy (energy threshold). The detector sensitivity to γ-rays was also analyzed and the operational range in which the γ-ray contribution to the signal is not negligible was determined. It is found that this detector can reach a maximum neutron efficiency of ∼1×10{sup −3} counts/n at 2.5 MeV (U{sub DD} sub-unit) and of ∼4×10{sup −3} counts/n at 14 MeV (U{sub DT} and U{sub DD} sub-units)

  6. Stochastic noise characteristics in matrix inversion tomosynthesis (MITS).

    Science.gov (United States)

    Godfrey, Devon J; McAdams, H P; Dobbins, James T Third

    2009-05-01

    Matrix inversion tomosynthesis (MITS) uses known imaging geometry and linear systems theory to deterministically separate in-plane detail from residual tomographic blur in a set of conventional tomosynthesis ("shift-and-add") planes. A previous investigation explored the effect of scan angle (ANG), number of projections (N), and number of reconstructed planes (NP) on the MITS impulse response and modulation transfer function characteristics, and concluded that ANG = 20 degrees, N = 71, and NP = 69 is the optimal MITS imaging technique for chest imaging on our prototype tomosynthesis system. This article examines the effect of ANG, N, and NP on the MITS exposure-normalized noise power spectra (ENNPS) and seeks to confirm that the imaging parameters selected previously by an analysis of the MITS impulse response also yield reasonable stochastic properties in MITS reconstructed planes. ENNPS curves were generated for experimentally acquired mean-subtracted projection images, conventional tomosynthesis planes, and MITS planes with varying combinations of the parameters ANG, N, and NP. Image data were collected using a prototype tomosynthesis system, with 11.4 cm acrylic placed near the image receptor to produce lung-equivalent beam hardening and scattered radiation. Ten identically acquired tomosynthesis data sets (realizations) were collected for each selected technique and used to generate ensemble mean images that were subtracted from individual image realizations prior to noise power spectra (NPS) estimation. NPS curves were normalized to account for differences in entrance exposure (as measured with an ion chamber), yielding estimates of the ENNPS for each technique. Results suggest that mid- and high-frequency noise in MITS planes is fairly equivalent in magnitude to noise in conventional tomosynthesis planes, but low-frequency noise is amplified in the most anterior and posterior reconstruction planes. Selecting the largest available number of projections (N

  7. Final Technical Report for the MIT Annular Fuel Research Project

    Energy Technology Data Exchange (ETDEWEB)

    Mujid S. Kazimi; Pavel Hejzlar

    2008-01-31

    MIT-NFC-PR-082 (January 2006) Abstract This summary provides an overview of the results of the U.S. DOE funded NERI (Nuclear Research ENergy Initiative) program on development of the internally and externally cooled annular fuel for high power density PWRs. This new fuel was proposed by MIT to allow a substantial increase in poer density (on the order of 30% or higher) while maintaining or improving safety margins. A comprehensive study was performed by a team consisting of MIT (lead organization), Westinghuse Electric Corporation, Gamma Engineering Corporation, Framatome ANP(formerly Duke Engineering) and Atomic Energy of Canada Limited.

  8. Quality control for the first large areas of triple GEM chambers for the CMS endcaps

    CERN Document Server

    Tytgat, Michael

    2015-01-01

    The CMS GEM collaboration plans to equip the very forward muon system with triple GEM detectors that can withstand the environment of the high-luminosity LHC. This project is at the final stages of R and D and moving to production. An unprecedented large area of several 100m2 are to be instrumented with GEM detectors which will be produced in six different sites around the world. A common construction and quality control procedure is required to ensure the performance of each detector. The quality control steps will include optical inspection, cleaning and baking of all materials and parts used to build the detector, leakage current tests of the GEM foils, high voltage tests, gas leak tests of the chambers and monitoring pressure drop vs. time, gain calibration to know the optimal operation region of the detector, gain uniformity tests, and studying the efficiency, noise and tracking performance of the detectors in a cosmic stand using scintillators.

  9. The gain in Thick GEM multipliers and its time-evolution

    CERN Document Server

    Alexeev, M; Bradamante, F; Bressan, A; Buechele, M; Chiosso, M; Ciliberti, P; Dalla Torre, S; Dasgupta, S; Denisov, O; Duic, V; Finger, M; Finger Jr, M; Fischer, H; Gobbo, B; Gregori, M; Herrmann, F; Koenigsmann, K; Levorato, S; Maggiora, A; Makke, N; Martin, A; Menon, G; Novakova, K; Novy, J; Panzieri, D; Pereira, F A; Santos, C A; Sbrizzai, G; Schiavon, P; Schopferer, S; Slunecka, M; Sozzi, F; Steiger, L; Sulc, M; Takekawa, S; Tessarotto, F; Veloso, J F C A

    2016-01-01

    In the context of a project to upgrade the gas photon detectors of COMPASS RICH-1, we have performed an R&D programme aimed to develop photon detectors based on multi-layer arrangements of thick GEM electron multipliers coupled to a CsI photoconverter. For this purpose, thick GEMs have been characterised in detail including the gain performance, its dependance on the geometrical parameters and its time-evolution, a feature exhibited by the gas detectors with open insulator surfaces. The variation due to this evolution drammatically depends on the parameters themselves. In the present article we summarise the outcomes of the studies dedicated to the thick GEM gain and its evolution versus time. We also include a qualitative model which accounts for the peculiar details of the observed thick GEM gain time-evolution.

  10. Fine-pitch glass GEM for high-resolution X-ray imaging

    Science.gov (United States)

    Fujiwara, T.; Mitsuya, Y.; Toyokawa, H.

    2016-12-01

    We have developed a fine-pitch glass gas electron multiplier (G-GEM) for high-resolution X-ray imaging. The fine-pitch G-GEM is made of a 400 μm thick photo-etchable glass substrate with 150 μm pitch holes. It is fabricated using the same wet etching technique as that for the standard G-GEM. In this work, we present the experimental results obtained with a single fine-pitch G-GEM with a 50 × 50 mm2 effective area. We recorded an energy resolution of 16.2% and gas gain up to 5,500 when the detector was irradiated with 5.9 keV X-rays. We present a 50 × 50 mm2 X-ray radiograph image acquired with a scintillation gas and optical readout system.

  11. Discriminating cosmic muons and X-rays based on rise time using a GEM detector

    Science.gov (United States)

    Wu, Hui-Yin; Zhao, Sheng-Ying; Wang, Xiao-Dong; Zhang, Xian-Ming; Qi, Hui-Rong; Zhang, Wei; Wu, Ke-Yan; Hu, Bi-Tao; Zhang, Yi

    2016-08-01

    Gas electron multiplier (GEM) detectors have been used in cosmic muon scattering tomography and neutron imaging over the last decade. In this work, a triple GEM device with an effective readout area of 10 cm × 10 cm is developed, and a method of discriminating between cosmic muons and X-rays based on rise time is tested. The energy resolution of the GEM detector is tested by 55Fe ray source to prove the GEM detector has a good performance. Analysis of the complete signal-cycles allows us to get the rise time and pulse heights. The experiment result indicates that cosmic muons and X-rays can be discriminated with an appropriate rise time threshold. Supported by National Natural Science Foundation of China (11135002, 11275235, 11405077, 11575073)

  12. Thermal neutron response of a boron-coated GEM detector via GEANT4 Monte Carlo code.

    Science.gov (United States)

    Jamil, M; Rhee, J T; Kim, H G; Ahmad, Farzana; Jeon, Y J

    2014-10-22

    In this work, we report the design configuration and the performance of the hybrid Gas Electron Multiplier (GEM) detector. In order to make the detector sensitive to thermal neutrons, the forward electrode of the GEM has been coated with the enriched boron-10 material, which works as a neutron converter. A total of 5×5cm(2) configuration of GEM has been used for thermal neutron studies. The response of the detector has been estimated via using GEANT4 MC code with two different physics lists. Using the QGSP_BIC_HP physics list, the neutron detection efficiency was determined to be about 3%, while with QGSP_BERT_HP physics list the efficiency was around 2.5%, at the incident thermal neutron energies of 25meV. The higher response of the detector proves that GEM-coated with boron converter improves the efficiency for thermal neutrons detection.

  13. MIT gets good marks for fighting gender discrimination

    Science.gov (United States)

    Gwynne, Peter

    2011-05-01

    The Massachusetts Institute of Technology (MIT) has made "significant progress" in increasing the number of female faculty members, with their numbers in science and engineering almost doubling over the last decade.

  14. Nichterkennen von Vorhofflimmern bei Patienten mit kardialer Resynchronisationstherapie

    Directory of Open Access Journals (Sweden)

    Strohmer B

    2005-01-01

    Full Text Available Obwohl eine Intoleranz der kardialen Resynchronisationstherapie (CRT unüblich ist, sollten entsprechende Symptome auf ihre Ursache hin genau abgeklärt werden. Atriale Tachyarrhythmien (AT werden bei Patienten mit chronischer Herzinsuffizienz relativ häufig beobachtet. Dieser Bericht beschreibt ein rhythmologisches Problem, welches oft unerkannt bleibt und in unserem CRTKollektiv bei knapp 8 % der Patienten aufgetreten ist. Paroxysmales Vorhofflattern wurde durch den CRT-Schrittmacher nicht erkannt, da jede zweite Flatterwelle exakt mit der atrialen Ausblendzeit (PVAB = postventrikuläres atriales Blanking zusammenfiel. Dies führte zu einem Versagen der Mode-Switch-Funktion durch Nichterkennung von stabilem Vorhofflattern, welches mit sehr stabiler Zykluslänge auftrat. Dieses sog. "2:1-lock-in"-Phänomen resultierte in rascher und anhaltender biventrikulärer Stimulation, welche sich bei den betroffenen Patienten klinisch als unangenehmes Herzklopfen mit zunehmender Atemnot bemerkbar machte.

  15. Therapie mit Vitamin D: Gibt es Grenzen?

    Directory of Open Access Journals (Sweden)

    Scharla SH

    2014-01-01

    Full Text Available Vitamin D wird in der Leber zum 25-Hydroxyvitamin D umgewandelt, welches die Speicherform darstellt. Die Serumkonzentration von 25-Hydroxyitamin D ist ein Maß für die Vitamin- D-Versorgung. In der Niere wird die Hormonform von Vitamin D, das 1,25-Dihydroxyvitamin D (= Calcitriol oder D-Hormon, hergestellt (endokrine Funktion, aber auch einige extrarenale Gewebe können Calcitriol lokal bilden (autokrine und parakrine Wirkung. Calcitriol hat pleiotrope Effekte: Neben dem Mineralhaushalt werden auch Immunsystem, Zelldifferenzierung, Insulinwirkung und kardiovaskuläres System beeinflusst. Die Therapie mit Vitamin D wird deshalb heute nicht nur zur Behandlung von Störungen des Mineralhaushaltes, sondern auch zur Prävention und Therapie von Infektionen, Autoimmunerkrankungen, Krebs, Bluthochdruck und Herzerkrankungen propagiert. Derzeit fehlen jedoch noch vielfach kontrollierte Studien, die den Nutzen einer Vitamin-D-Behandlung außerhalb von Risikogruppen nachweisen oder die prophylaktische Vitamin-D-Supplementation der allgemeinen Bevölkerung rechtfertigen würden. Überdies ist Vorsicht bei zu hohen Dosierungen geboten, da hohe Vitamin-D-Konzentrationen möglicherweise auch negative Effekte haben können. Die Anwendung einer Vitamin-D-Stoßtherapie (hohe Einmaldosierung ist obsolet.

  16. Systematic measurements of the gain and the energy resolution of single and double mask GEM detectors

    Energy Technology Data Exchange (ETDEWEB)

    Biswas, S., E-mail: saikat.ino@gmail.com [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstrasse 1, D-64291 Darmstadt (Germany); School of Physical Sciences, National Institute of Science Education and Research, Jatni 752050 (India); Schmidt, D.J. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstrasse 1, D-64291 Darmstadt (Germany); Abuhoza, A. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstrasse 1, D-64291 Darmstadt (Germany); King Abdulaziz City forv Science and Technology (KACST), Riyadh (Saudi Arabia); Frankenfeld, U.; Garabatos, C.; Hehner, J.; Kleipa, V.; Morhardt, T.; Schmidt, C.J. [GSI Helmholtzzentrum für Schwerionenforschung GmbH, Planckstrasse 1, D-64291 Darmstadt (Germany); Schmidt, H.R.; Wiechula, J. [Eberhard-Karls-Universität, Tübingen (Germany)

    2016-07-11

    Systematic studies on the gain and the energy resolution have been carried out by varying the voltage across the GEM foils for both single mask and double mask triple GEM detector prototypes. Variation of the gain and the energy resolution has also been measured by varying either the drift voltage, transfer voltage and induction voltage keeping other voltages constant. The results of the systematic measurements have been presented.

  17. BoNuS: Development and Use of a Radial TPC using Cylindrical GEMs

    Energy Technology Data Exchange (ETDEWEB)

    Howard Fenker; Nathan Baillie; Peter Bradshaw; S. Bultmann; Stephen Bueltmann; Volker Burkert; Michael Christy; Gail Dodge; Dipangkar Dutta; Rolf Ent; Josh Evans; Robert Fersch; Kevin Giovanetti; Keith Griffioen; Mikayel Ispiryan; Chandana Jayalath; Narbe Kalantarians; Cynthia Keppel; Sebastian Kuhn; Gabriel Niculescu; Maria-Ioana Niculescu; Svyatoslav Tkachenko; Vladas Tvaskis; Jixie Zhang

    2007-11-28

    To provide new access to information about nucleon structure from electron-neutron interactions, a specialized aystem of target and detector was developed at Jefferson Lab. It allows identification and measurement of spectator protons produced in e X scattering events. The detector is a radial time-projection chamber optimized for the acceptance of low-momentum protons. Gas gain is provided by three cascaded curved Gas Electron Multipliers (GEMs), the first application of GEMs in any configuration other than flat.

  18. Entwicklung einer Spurendriftkammer mit Mikrostreifenauslese für Schwerionenexperimente

    OpenAIRE

    Frankenfeld, Ulrich

    1996-01-01

    Im Rahmen dieser Arbeit wurde ein Prototyp einer Spurendriftkammer mit Mikrostreifenauslese, wie sie als hochauflösende Spurendetektoren in der Kern- und Teilchenphysik zum Einsatz kommen sollen, konstruiert und getestet. Besonderes Augenmerk lag hierbei auf der Signalform und -verteilung, sowie auf dem Langzeitverhalten. Für die verschiedenen Messungen dieser Arbeit wurden die Mikrostreifen-Gasdetektoren in ein Edelstahlrohr eingebaut, das mit einem Vakuumpumpen-System verbunden ist. Durch E...

  19. Signalling via MHC class II molecules modifies the composition of GEMs in APC.

    Science.gov (United States)

    Setterblad, N; Becart, S; Charron, D; Mooney, N

    2001-01-01

    Major histocompatibility complex (MHC) class II molecules are responsible for peptide presentation to helper T lymphocytes and as such play an essential role in the immune response. These molecules transmit intracellular signals leading to diverse consequences in B lymphocytes including proliferation and apoptosis. Recent studies have revealed that glycolipid enriched membrane microdomains (GEMs) behave as signalling platforms for a variety of lymphocyte receptors. We have quantified human leucocyte antigen (HLA)-DR molecules localized in GEMs in human B lymphocytes. Use of a model imitating the interaction of HLA-DR with a T-cell receptor (TCR) modified the constituents of the HLA-DR-enriched GEMs. Confocal microscopy demonstrated a recruitment of HLA-DR and the ganglioside GM1 at the site of HLA-DR interaction with the stimulating ligand. Moreover, cholesterol depletion efficiently impaired this recruitment. Co-localizing proteins detected in HLA-DR-enriched GEMs include protein kinase C (PKC)-delta and actin. These data reveal that MHC class II antigens are localized in GEMs in mature human B lymphocytes and indicates that the formation of the immunological synapse regulates the composition of HLA-DR enriched GEMs in the antigen presenting cell (APC).

  20. STATUS REPORT ON THE CMS FORWARD MUON UPGRADE WITH LARGE-SIZE TRIPLE-GEM DETECTORS

    CERN Document Server

    Barria, Patrizia

    2014-01-01

    For the LHC High Luminosity phase (HL-LHC) the CMS GEM Collaboration is planning to install new large size (990 x 440-220 mm2) triple-GEM detectors, equipped with a new readout system, in the forward region of the muon system (1.5 lt IηI lt 2.2) of the CMS detector. Combining triggering and tracking functionalities the new triple-Gas Electron Multiplier (GEM) chambers will not only improve the performance of the CMS muon trigger, but will also improve the muon identification and track reconstruction. With the addition of triple-GEM detectors the forward region of the CMS muon spectrometer will recover its originally planned redundancy. Starting from 2009 the CMS GEM Collaboration built several small and full size prototypes with different geometries, keeping improving the assembly techniques. All these prototypes have been tested in laboratories as well as with beam tests at the CERN SPS and at Fermilab. The results show that the triple-GEM detectors are a mature technology satisfying all the requirements ...

  1. Investigation of GEM-Micromegas detector on X-ray beam of synchrotron radiation

    Science.gov (United States)

    Zhang, Yu-Lian; Qi, Hui-Rong; Hu, Bi-Tao; Fan, Sheng-Nan; Wang, Bo; Liu, Mei; Zhang, Jian; Liu, Rong-Guang; Chang, Guang-Cai; Liu, Peng; Ouyang, Qun; Chen, Yuan-Bo; Yi, Fu-Ting

    2014-04-01

    To reduce the discharge of the standard bulk Micromegas and GEM detectors, a GEM-Micromegas detector was developed at the Institute of High Energy Physics. Taking into account the advantages of the two detectors, one GEM foil was set as a preamplifier on the mesh of Micromegas in the structure and the GEM preamplification decreased the working voltage of Micromegas to significantly reduce the effect of the discharge. At the same gain, the spark probability of the GEM-Micromegas detector can be reduced to a factor 0.01 compared to the standard Micromegas detector, and an even higher gain could be obtained. This paper describes the performance of the X-ray beam detector that was studied at 1W2B Laboratory of Beijing Synchrotron Radiation Facility. Finally, the result of the energy resolution under various X-ray energies was given in different working gases. This indicates that the GEM-Micromegas detector has an energy response capability in an energy range from 6 keV to 20 keV and it could work better than the standard bulk-Micromegas.

  2. Evaluation of ozone profile and tropospheric ozone retrievals from GEMS and OMI spectra

    Directory of Open Access Journals (Sweden)

    J. Bak

    2013-02-01

    Full Text Available South Korea is planning to launch the GEMS (Geostationary Environment Monitoring Spectrometer instrument into the GeoKOMPSAT (Geostationary Korea Multi-Purpose SATellite platform in 2018 to monitor tropospheric air pollutants on an hourly basis over East Asia. GEMS will measure backscattered UV radiances covering the 300–500 nm wavelength range with a spectral resolution of 0.6 nm. The main objective of this study is to evaluate ozone profiles and stratospheric column ozone amounts retrieved from simulated GEMS measurements. Ozone Monitoring Instrument (OMI Level 1B radiances, which have the spectral range 270–500 nm at spectral resolution of 0.42–0.63 nm, are used to simulate the GEMS radiances. An optimal estimation-based ozone profile algorithm is used to retrieve ozone profiles from simulated GEMS radiances. Firstly, we compare the retrieval characteristics (including averaging kernels, degrees of freedom for signal, and retrieval error derived from the 270–330 nm (OMI and 300–330 nm (GEMS wavelength ranges. This comparison shows that the effect of not using measurements below 300 nm on retrieval characteristics in the troposphere is insignificant. However, the stratospheric ozone information in terms of DFS decreases greatly from OMI to GEMS, by a factor of ∼2. The number of the independent pieces of information available from GEMS measurements is estimated to 3 on average in the stratosphere, with associated retrieval errors of ~1% in stratospheric column ozone. The difference between OMI and GEMS retrieval characteristics is apparent for retrieving ozone layers above ~20 km, with a reduction in the sensitivity and an increase in the retrieval errors for GEMS. We further investigate whether GEMS can resolve the stratospheric ozone variation observed from high vertical resolution Earth Observing System (EOS Microwave Limb Sounder (MLS. The differences in stratospheric ozone profiles between GEMS and MLS are comparable to those

  3. Rigiscan®-Monitoring der Erektion unter audiovisueller sexueller Stimulation ohne/mit Viagra™ bei Patienten mit erektiler Dysfunktion

    Directory of Open Access Journals (Sweden)

    Perabo FGE

    2000-01-01

    Full Text Available Die orale Medikation mit Sildenafil (Viagra™ hat sich zur Therapie der erektilen Dysfunktion etabliert und relativiert die Differentialdiagnose zwischen psychogener und organischer Dysfunktion mit den entsprechenden therapeutischen Konsequenzen. Diesem Problem widmet sich diese Studie zur Prüfung der erektilen Antwort unter RigiScan®-Monitoring ohne/mit 50 mg Viagra™. 64 Patienten (mittleres Alter 48 Jahre mit einer erektilen Dysfunktion arteriogener (n = 10, venöser (n = 7, gemischt neurogen/vaskulärer (n = 15 und psychogener (n = 32 Genese von mehr als 6 Monaten Dauer wurden in die Studie aufgenommen. Alle Patienten wurden eingehend diagnostisch abgeklärt, inklusive Hormonlabor, dynamischer Pharmako-Duplexsonographie und, falls indiziert, mit einer Cavernosometrie/ -graphie. Zur Testung der penilen Rigidität und zur Objektivierung der Erektion wurde das "real-time" RigiScan® verwendet. In zwei konsekutiven Messungen wurden sowohl die direkte erektile Antwort auf visuelle Stimulation als auch die nächtlichen Erektionen abgeleitet und die Meßergebnisse mit den Begleiterkrankungen, "lifestyle"-Faktoren und dem Ergebnis der Pharmako-Duplexsonographie korreliert. Es fand sich keine Korrelation zwischen der Ätiologie der erektilen Dysfunktion in bezug auf organische oder psychogene Genese und dem Alter der Patienten, der Dauer der Erektionsstörung, dem Nikotinabusus, den Blutfetten, den Testosteronwerten, dem klinischen Ergebnis der Pharmakotestung (Erektionsgrad und dem duplexsonographisch gemessenen Fluß der penilen Arterien. Hingegen zeigte sich eine positive Korrelation zwischen Genese der erektilen Dysfunktion (organisch bzw. psychogen und dem RigiScan®-Meßergebnis (r = 0,29. Patienten mit psychogen bedingter Erektionsstörung profitierten am meisten von Viagra™, während Patienten mit vaskulärer Genese oder gemischt neurogener/vaskulärer Genese deutlich schlechter auf Viagra™ ansprachen. Es bestand keine Korrelation

  4. GEM*STAR: Time for an Alternative Way Forward

    Science.gov (United States)

    Vogelaar, R. Bruce

    2011-10-01

    The presumption that nuclear reactors will retain their role in global energy production is constantly being challenged - even more so following recent events at Fukushima. Nuclear energy, despite being ``green,'' has inexorably been coupled in the public mind with three paramount concerns: safety, weapons proliferation, and waste (and then ultimately cost). Over the past four decades, the safety of deployed fleets has greatly improved, yet the capital and political costs of a ``nuclear energy option'' appear insurmountable in several countries. The US approach to civilian nuclear energy has become deeply entrenched, first through choices made by the military, and then by the deployed nuclear reactor fleet. This extends to the research agencies as well, to the point where basic sciences and nuclear energy operate in separate spheres. But technologies and priorities have changed, and the time has arrived where a transformative re-think of nuclear energy is not only possible, but urgent. And nuclear physicists are uniquely positioned to accomplish this. This talk will show that by asking, and answering,``what would an accelerator-driven civilian nuclear energy program look like,'' ADNA Corporation's GEM*STAR design directly addresses all three fundamental concerns: safety, proliferation, and waste - and also the final hurdle: cost. GEM*STAR is not an ``add-on'' (to either Project-X, or GEN III+), but rather a base-line energy production capacity, for either electricity or transport fuel production. It integrates and advances the molten-salt reactor technology developed at ORNL, the MW beam accelerator technologies developed by basic sciences, and a reactor/target design optimized for accelerator driven-systems. The results include: the ability to use LWR spent fuel without reprocessing or additional waste; the ability to use natural uranium; no critical mass ever present; orders-of-magnitude less volatile radioactivity in the core; more efficient use of, and deeper

  5. Quality Control (QC2) of Gas Electron Multiplier (GEM) for GE1/1 at CMS Experiment

    CERN Document Server

    Sharma, Archana

    2016-01-01

    Gas Electron Multiplier (GEM) is a gas ionization detector that detect charged particles and will be implemented on CMS system. It is designed to improve muon trigger and tracking performance at high luminosity after the second Long Shutdown (LS2). For my project, GEM foils, a component of the Triple GEM detector have been studied. In order to pass the test, the foils need to run in the Fast Test and Long Test of QC2.

  6. First performance of the gems + gmos system. Part1. Imaging

    CERN Document Server

    Hibon, Pascale; Neichel, Benoit; Prout, Benjamin; Rigaut, Francois; Koning, Alice; Carrasco, Eleazar R; Gimeno, German; Pessev, Peter

    2016-01-01

    During the commissioning of the Gemini MCAO System (GeMS), we had the opportunity to obtain data with the Gemini Multi-Object Spectrograph (GMOS), the most utilised instrument at Gemini South Observatory, in March and May 2012. Several globular clusters were observed in imaging mode that allowed us to study the performance of this new and untested combination. GMOS is a visible instrument, hence pushing MCAO toward the visible.We report here on the results with the GMOS instruments, derive photometric performance in term of Full Width Half Maximum (FWHM) and throughput. In most of the cases, we obtained an improvement factor of at least 2 against the natural seeing. This result also depends on the Natural Guide Star constellation selected for the observations and we then study the impact of the guide star selection on the FWHM performance.We also derive a first astrometric analysis showing that the GeMS+GMOS system provide an absolute astrometric precision better than 8mas and a relative astrometric precision...

  7. An Interactive Java Statistical Image Segmentation System: GemIdent.

    Science.gov (United States)

    Holmes, Susan; Kapelner, Adam; Lee, Peter P

    2009-06-01

    Supervised learning can be used to segment/identify regions of interest in images using both color and morphological information. A novel object identification algorithm was developed in Java to locate immune and cancer cells in images of immunohistochemically-stained lymph node tissue from a recent study published by Kohrt et al. (2005). The algorithms are also showing promise in other domains. The success of the method depends heavily on the use of color, the relative homogeneity of object appearance and on interactivity. As is often the case in segmentation, an algorithm specifically tailored to the application works better than using broader methods that work passably well on any problem. Our main innovation is the interactive feature extraction from color images. We also enable the user to improve the classification with an interactive visualization system. This is then coupled with the statistical learning algorithms and intensive feedback from the user over many classification-correction iterations, resulting in a highly accurate and user-friendly solution. The system ultimately provides the locations of every cell recognized in the entire tissue in a text file tailored to be easily imported into R (Ihaka and Gentleman 1996; R Development Core Team 2009) for further statistical analyses. This data is invaluable in the study of spatial and multidimensional relationships between cell populations and tumor structure. This system is available at http://www.GemIdent.com/ together with three demonstration videos and a manual.

  8. Radiation Tests for a Single-GEM Loaded Gaseous Detector

    CERN Document Server

    Lee, Kyong Sei; Kim, Sang Yeol; Park, Sung Keun

    2014-01-01

    We report on the systematic study of a single-gas-electron-multiplication (GEM) loaded gaseous detector developed for precision measurements of high-energy particle beams and dose-verification measurements. In the present study, a 256-channel prototype detector with an active area of 16$\\times$16 cm$^{2}$, operated in a continuous current-integration-mode signal-processing method, was manufactured and tested with x rays emitted from a 70-kV x-ray generator and 43-MeV protons provided by the MC50 proton cyclotron at the Korea Institute of Radiological and Medical Science (KIRAMS). The amplified detector response was measured for the x rays with an intensity of about 5$\\times$10$^{6}$ Hz cm$^{-2}$. The linearity of the detector response to the particle flux was examined and validated by using 43-MeV proton beams. The non-uniform development of the amplification for the gas electrons in space was corrected by applying proper calibration to the channel responses of the measured beam-profile data. We concluded fro...

  9. Testing of triple-GEM chambers for CBM experiment at FAIR using self-triggered readout electronics

    Energy Technology Data Exchange (ETDEWEB)

    Dubey, A.K. [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700064 (India); Chattopadhyay, S., E-mail: sub@vecc.gov.in [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700064 (India); Saini, J.; Singaraju, R.; Murthy, G.S.N.; Viyogi, Y.P. [Variable Energy Cyclotron Centre, 1/AF Bidhan Nagar, Kolkata 700064 (India); Abuhoza, A.; Biswas, S.; Frankenfeld, U.; Hehner, J.; Kleipa, V.; Morhardt, Th.; Schmidt, C.J.; Schmidt, D.J. [GSI Helmholtzzentrum fur Schwerionenforschung GmbH, Darmstadt (Germany); Lymanets, A.; Schmidt, H.R. [Physikalisches Institut - Eberhard Karls Universitat Tubingen, D-72076 Tubingen (Germany)

    2014-08-01

    Triple GEM chamber has been selected to be used for the muon detection system (MUCH) in the Compressed Baryonic Matter (CBM) experiment at the upcoming Facility for the Antiproton and Ion Research (FAIR). Two prototype triple-GEM chambers filled with the mixture of argon and CO{sub 2} gases in the ratio of 70:30 were made of small-size (10 cm×10 cm) single-mask GEM foils and read by a self-triggered readout ASIC called nXYTER have been tested with pion beams at CERN. The readout electronics records the arrival times of GEM hits and of corresponding coincidence trigger signals separately. The distribution of time difference between GEM hits and respective triggers shows a peak demonstrating the time correlation between GEM hits and the trigger. The width (σ) of the time-correlation peak, which is related to the time resolution of the chamber, reduces with voltage approaching ≈12 ns at ΔV{sub GEM} of 335 V. Considering the hits inside the time-correlation peak to correspond to the beam trigger, the efficiency reaches a plateau at 95% at Δ{sub GEM} above 330 V. For a readout plane segmented by 3 mm×3 mm pads, on an average 1.2 pads are fired per trigger for pion beams at the operating voltage. The chamber shows a gain of ≈4000 at ΔV{sub GEM} of 350 V.

  10. Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handling.

    Directory of Open Access Journals (Sweden)

    Jenny E Gunton

    Full Text Available AIMS AND HYPOTHESIS: Glucose-stimulated insulin secretion from beta-cells is a tightly regulated process that requires calcium flux to trigger exocytosis of insulin-containing vesicles. Regulation of calcium handling in beta-cells remains incompletely understood. Gem, a member of the RGK (Rad/Gem/Kir family regulates calcium channel handling in other cell types, and Gem over-expression inhibits insulin release in insulin-secreting Min6 cells. The aim of this study was to explore the role of Gem in insulin secretion. We hypothesised that Gem may regulate insulin secretion and thus affect glucose tolerance in vivo. METHODS: Gem-deficient mice were generated and their metabolic phenotype characterised by in vivo testing of glucose tolerance, insulin tolerance and insulin secretion. Calcium flux was measured in isolated islets. RESULTS: Gem-deficient mice were glucose intolerant and had impaired glucose stimulated insulin secretion. Furthermore, the islets of Gem-deficient mice exhibited decreased free calcium responses to glucose and the calcium oscillations seen upon glucose stimulation were smaller in amplitude and had a reduced frequency. CONCLUSIONS: These results suggest that Gem plays an important role in normal beta-cell function by regulation of calcium signalling.

  11. Demenz und Depression bei Patienten mit idiopathischem Parkinson-Syndrom

    Directory of Open Access Journals (Sweden)

    Herting B

    2007-01-01

    Full Text Available Das idiopathische Parkinson-Syndrom (IPS ist eine progressive neurodegenerative Erkrankung mit motorischen und nicht-motorischen Symptomen. Bei Patienten mit IPS sind kognitive Defizite und Demenzen mit einer Prävalenz von 20–40 % nachgewiesen worden. Risikofaktoren für das Auftreten einer Parkinson-Demenz (PDe sind hohes Alter bei Krankheitsbeginn, schwere und/oder beidseitige motorische Symptomatik, Verwirrtheitszustände unter Levodopa-Medikation, aber auch Demenzerkrankungen in der Familie und niedriges Bildungsniveau. Patienten mit PDe weisen eine erhöhte Morbidität und Mortalität im Vergleich zu Patienten mit IPS ohne Demenz und der altersgleichen Normalbevölkerung auf, die unabhängig von der Schwere der motorischen Einbußen zweifach erhöht ist. Die Depression ist das häufigste psychiatrische Symptom beim IPS (die Angaben zur Prävalenz schwanken zwischen 4 % und 70 % und beeinflußt neben den Aktivitäten des täglichen Lebens wesentlich die Lebensqualität der Betroffenen. Darin liegt auch die Herausforderung, kognitive und affektive Symptome effizient zu behandeln.

  12. The micro turbine: the MIT example; La micro turbine: l'exemple du MIT

    Energy Technology Data Exchange (ETDEWEB)

    Ribaud, Y. [Office National d' Etudes et de Recherches Aerospatiales (ONERA-DEFA), 92 - Chatillon (France)

    2001-10-01

    The micro turbine study began a few years ago at the MIT, with the participation of specialists from different fields. The purpose is the development of a MEMS (micro electro mechanical systems) based, 1 cm in diameter, micro gas turbine. Potential applications are devoted to micro drone propulsion, electric power generation for portable power sources in order to replace heavy Lithium batteries, satellite motorization, the surface distributed power for boundary suction on plane wings. The manufacturing constraints at such small scales lead to 2-D extruded shapes. The physical constraints stem from viscous effects and from limitations given by 2-D geometry. The time scales are generally shorter than for conventional machines. Otherwise the material properties are better at such length scales. Transposition from conventional turbomachinery laws is no more applicable and new design methods must be established. The present paper highlights the project progress and the technology breakthroughs. (author)

  13. Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) GEM Manual

    Energy Technology Data Exchange (ETDEWEB)

    C. L. Smith; J. Schroeder; S. T. Beck

    2008-08-01

    The Systems Analysis Programs for Hands-on Integrated Reliability Evaluations (SAPHIRE) is a software application developed for performing a complete probabilistic risk assessment (PRA) using a personal computer running the Microsoft Windows? operating system. SAPHIRE is primarily funded by the U.S. Nuclear Regulatory Commission (NRC) and developed by the Idaho National Laboratory (INL). The INL's primary role in this project is that of software developer and tester. Using the SAPHIRE analysis engine and relational database is a complementary program called GEM. GEM has been designed to simplify using existing PRA analysis for activities such as the NRC’s Accident Sequence Precursor program. In this report, the theoretical framework behind GEM-type calculations are discussed in addition to providing guidance and examples for performing evaluations when using the GEM software. As part of this analysis framework, the two types of GEM analysis are outlined, specifically initiating event (where an initiator occurs) and condition (where a component is failed for some length of time) assessments.

  14. Gravity model improvement using GEOS 3 /GEM 9 and 10/. [and Seasat altimetry data

    Science.gov (United States)

    Lerch, F. J.; Wagner, C. A.; Klosko, S. M.; Laubscher, R. E.

    1979-01-01

    Although errors in previous gravity models have produced large uncertainties in the orbital position of GEOS 3, significant improvement has been obtained with new geopotential solutions, Goddard Earth Model (GEM) 9 and 10. The GEM 9 and 10 solutions for the potential coefficients and station coordinates are presented along with a discussion of the new techniques employed. Also presented and discussed are solutions for three fundamental geodetic reference parameters, viz. the mean radius of the earth, the gravitational constant, and mean equatorial gravity. Evaluation of the gravity field is examined together with evaluation of GEM 9 and 10 for orbit determination accuracy. The major objectives of GEM 9 and 10 are achieved. GEOS 3 orbital accuracies from these models are about 1 m in their radial components for 5-day arc lengths. Both models yield significantly improved results over GEM solutions when compared to surface gravimetry, Skylab and GEOS 3 altimetry, and highly accurate BE-C (Beacon Explorer-C) laser ranges. The new values of the parameters discussed are given.

  15. The geology, mineralogy and rare element geochemistry of the gem deposits of Sri Lanka

    Directory of Open Access Journals (Sweden)

    C. B. Dissanayake

    2000-01-01

    Full Text Available The gem deposits of Sri Lanka are studied from the point of view of their geology, mineralogy and geochemistry. Nearly all the gem formations are located in the central high-grade metamorphic terrain of the Highland Complex. The gem deposits are classified as sedimentary, metamorphic and magmatic; the sedimentary types being the most abundant. The mineralogy of the gem deposits varies widely with, among others, corundum, chrysoberyl, beryl, spinel, topaz,zircon, tourmaline, garnet and sphene being common.Rare element concentrations in sediments from the three main gem fields of Sri Lanka, namely Ratnapura, Elahera and Walawe, were studied. It was found that some sediments are considerably enriched in certain elements compared to their average continental crustal abundances. The Walawe Ganga sediments show anomalous enrichments of the high field strength and associated elements, particularly Zr, Hf, W and Ti. This is attributed to the presence of accessory mineralssuch as zircon, monazite and rutile. Some of these heavy minerals comprise as much as 50 wt% of sediment. The geochemical enrichment of some trace elements compared to their average crustal abundances indicates that highly differentiated granites and associated pegmatites have provided the source materials for enrichment.

  16. Gaseous elemental mercury (GEM) emissions from snow surfaces in northern New York.

    Science.gov (United States)

    Maxwell, J Alexander; Holsen, Thomas M; Mondal, Sumona

    2013-01-01

    Snow surface-to-air exchange of gaseous elemental mercury (GEM) was measured using a modified Teflon fluorinated ethylene propylene (FEP) dynamic flux chamber (DFC) in a remote, open site in Potsdam, New York. Sampling was conducted during the winter months of 2011. The inlet and outlet of the DFC were coupled with a Tekran Model 2537A mercury (Hg) vapor analyzer using a Tekran Model 1110 two port synchronized sampler. The surface GEM flux ranged from -4.47 ng m(-2) hr(-1) to 9.89 ng m(-2) hr(-1). For most sample periods, daytime GEM flux was strongly correlated with solar radiation. The average nighttime GEM flux was slightly negative and was not well correlated with any of the measured meteorological variables. Preliminary, empirical models were developed to estimate GEM emissions from snow surfaces in northern New York. These models suggest that most, if not all, of the Hg deposited with and to snow is reemitted to the atmosphere.

  17. The HadGEM2 family of Met Office Unified Model Climate configurations

    Directory of Open Access Journals (Sweden)

    The HadGEM2 Development Team: Martin, G. M.

    2011-04-01

    Full Text Available We describe the HadGEM2 family of climate configurations of the Met Office Unified Model, MetUM. The concept of a model "family" comprises a range of specific model configurations incorporating different levels of complexity but with a common physical framework. The HadGEM2 family of configurations includes atmosphere and ocean components, with and without a vertical extension to include a well-resolved stratosphere, and an Earth-System (ES component which includes dynamic vegetation, ocean biology and atmospheric chemistry. The HadGEM2 physical model includes improvements designed to address specific systematic errors encountered in the previous climate configuration, HadGEM1, namely Northern Hemisphere continental temperature biases and tropical sea surface temperature biases and poor variability. Targeting these biases was crucial in order that the ES configuration could represent important biogeochemical climate feedbacks. Detailed descriptions and evaluations of particular HadGEM2 family members are included in a number of other publications, and the discussion here is limited to a summary of the overall performance using a set of model metrics which compare the way in which the various configurations simulate present-day climate and its variability.

  18. The HadGEM2 family of Met Office Unified Model climate configurations

    Directory of Open Access Journals (Sweden)

    The HadGEM2 Development Team: G. M. Martin

    2011-09-01

    Full Text Available We describe the HadGEM2 family of climate configurations of the Met Office Unified Model, MetUM. The concept of a model "family" comprises a range of specific model configurations incorporating different levels of complexity but with a common physical framework. The HadGEM2 family of configurations includes atmosphere and ocean components, with and without a vertical extension to include a well-resolved stratosphere, and an Earth-System (ES component which includes dynamic vegetation, ocean biology and atmospheric chemistry. The HadGEM2 physical model includes improvements designed to address specific systematic errors encountered in the previous climate configuration, HadGEM1, namely Northern Hemisphere continental temperature biases and tropical sea surface temperature biases and poor variability. Targeting these biases was crucial in order that the ES configuration could represent important biogeochemical climate feedbacks. Detailed descriptions and evaluations of particular HadGEM2 family members are included in a number of other publications, and the discussion here is limited to a summary of the overall performance using a set of model metrics which compare the way in which the various configurations simulate present-day climate and its variability.

  19. Professionell entwickeln mit Java EE 7 das umfassende Handbuch

    CERN Document Server

    Salvanos, Alexander

    2014-01-01

    Ein praxisorientiertes Lehrbuch zur JEE 7 und zugleich ein Standardwerk, das Sie auf Ihrem Weg zum Enterprise-Entwickler begleitet. Inklusive Best Practices für leichtgewichtige Enterprise Applications, Standards zu servicebasierten Anwendungen, Persistence API, Dependency Injection, HTML5 und Performance-Tuning. Aus dem Inhalt: Grundlagen und Installation Software-Architektur mit Java EE Webanwendungen mit HTML5 und CSS3 Java Standard Tag Library Asynchrone Servlets und Non-blocking I/O Datenbanken anbinden mit der JDBC API Java Server Faces Datenbank-Organisation Java Persistence API Objektrelationales Mapping Transaktionssicherheit Performance-Tuning Internationalisierung Enterprise Java Beans WebSockets PrimeFaces Deployment Galileo Press heißt von jetzt an Rheinwerk Verlag.

  20. Islam, Migration und Integration: Konflikte jugendlicher Migranten mit islamischem Hintergrund

    Directory of Open Access Journals (Sweden)

    Ilhan Kizilhan

    2008-04-01

    Full Text Available Der Islam mit seinen verschiedenen Verhaltensweisen und Verboten spielt direkt oder indirekt immer noch eine wichtige Rolle im alltäglichen Leben vieler Migranten. Religiöse Vorschriften zeichnen sich dadurch aus, dass ihrer Achtung nicht juristisch, sondern durch sozialen Druck Nachdruck verliehen wird (Verwandtschaft, religiöse Lehrer, islamische Gemeinde, religiöse Vereine etc. und dass ihre Missachtung mit Folgen in Form von Ausgrenzung, Missachtung und Diskriminierung einhergeht. Die kulturellen Vorstellungen der ersten Generation unterscheiden sich auf Grund der unterschiedlichen Biografien von denen der zweiten und dritten durch den Grad der Verwurzelung in der kulturellen Identität und der Verbundenheit mit traditionellen Wertvorstellungen. Fehlende Integrationskonzepte, Ausgrenzung im Migrationsland auf der einen und weltweite staatliche und halbstaatliche Konflikte im Namen des Islams bis hin zum Terrorismus auf der anderen Seite haben einen erheblichen Einfluss auf den Integrationsgrad von jugendlichen Migranten im Aufnahmeland.

  1. Fallstudie SIG - Supply Chain Prototyp mit Coca Cola Beverages

    OpenAIRE

    Senger, Enrico

    2003-01-01

    SIG, ein führender Lieferant von Verpackungsmaterialien für Getränke, hat mit Coca Cola CPFR, collaborative planning, forecasting and replenishment realisiert. Das Unternehmen kann elektronisch und ohne Zeitverzug (vorher mit bis zu 15 Tagen Verspätung) auf die Lagerbestände und Verkaufsvorhersagen bei Coca Cola zugreifen. Coca Cola erhält die exakten Liefermengen und zeiten. Coca Cola konnte dadurch den Lagerbestand von Verpackungsmaterial um 50% senken. Dies reduziert die Bearbeitungszeit d...

  2. „Schloss mit der Debatte!“?

    OpenAIRE

    Birkholz, Tim

    2008-01-01

    Am 19. Januar 2006 beschloss der Deutsche Bundestag mit überwältigender Mehrheit den Abriss des Palastes der Republik. Kurz darauf wurde auf dem Schlossplatz im historischen Zentrum von Berlin mit dem Abtragen des in der Ära Honecker errichteten Gebäudes begonnen. In ähnlicher Deutlichkeit war bereits die Rekonstruktion des Berliner Schlosses beschlossen worden, welches zuvor an gleicher Stelle stehend von der DDR-Regierung unter Walter Ulbricht abgerissen worden war. Die Mehrheitsverhältniss...

  3. Study of electron focusing in thick GEM based photon detectors using semitransparent photocathodes

    Energy Technology Data Exchange (ETDEWEB)

    Baishali, G., E-mail: baishali@isu.iisc.ernet.in [Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore 560012 (India); Radhakrishna, V.; Koushal, V.; Rakhee, K. [Space Astronomy Group, ISRO Satellite Centre, Bangalore 560017 (India); Rajanna, K. [Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore 560012 (India)

    2013-11-21

    The detection efficiency of a GEM based UV sensitive gaseous photomultiplier (GPM) depends on the focusing of electrons from the drift gap to the GEM aperture. We have studied the effect of drift parameters on the efficiency of electron focusing into Thick GEM (THGEM) holes in a GPM with semitransparent UV photoconverter. This study comprises simulation of electron focusing into THGEM holes using GARFIELD for different Ar and Ne based gas mixtures and experimental investigations of the same with P10 gas mixture. -- Highlights: •Effect of drift parameters on detection efficiency of a THGEM based GPM is studied. •Drift parameters studied are drift field, drift gap, gas composition and pressure. •GARFIELD simulation on Electron Transfer Efficiency for various drift parameters. •Experimental studies were carried out for P10 gas at lower multiplication voltage. •Optimization of drift parameters for maximizing the detection efficiency.

  4. Analysis of parental strain DNA fragments existing in GEMs-Fhhh

    Institute of Scientific and Technical Information of China (English)

    HAO Chun-bo; YAN Jun; QU Meng-meng; WANG Dong; CHENG Shu-pei; GU Ji-dong; QIU Wan-fei; WANG Yin-yin

    2003-01-01

    There were 6 target DNA fragments of the three parental strains existing in the cell of GEMs(genetically engineered microorganism strain) Fhhh measured in this research by PCR(polymerase chain reaction). The determination showed that GEMs Fhhh contained all the 6 target DNA fragments, mnp1, mnp2、lip1、lip2, FLO1 and 16S rDNA, and had the molecular genetic stability. Meanwhile the PCR production of each parental strain could only had its target DNA fragments and was different from each other. It may illustrate that the technique of the inter-kingdom protoplast fusion for the construction of GEMs Fhhh through the process of intercellular gene recombination could be used as a reliable bioengineering technique to create the specific functional stain for the pollution control.

  5. Use of laser induced breakdown spectroscopy in the determination of gem provenance: beryls.

    Science.gov (United States)

    McManus, Catherine E; McMillan, Nancy J; Harmon, Russell S; Whitmore, Robert C; De Lucia, Frank C; Miziolek, Andrzej W

    2008-11-01

    The provenance of gem stones has been of interest to geologists, gemologists, archeologists, and historians for centuries. Laser induced breakdown spectroscopy (LIBS) provides a minimally destructive tool for recording the rich chemical signatures of gem beryls (aquamarine, goshenite, heliodor, and morganite). Broadband LIBS spectra of 39 beryl (Be(3)Al(2)Si(6)O(18)) specimens from 11 pegmatite mines in New Hampshire, Connecticut, and Maine (USA) are used to assess the potential of using principal component analysis of LIBS spectra to determine specimen provenance. Using this technique, beryls from the three beryl-bearing zones in the Palermo #1 pegmatite (New Hampshire) can be recognized. However, the compositional variation within this single mine is comparable to that in beryls from all three states. Thus, a very large database with detailed location metadata will be required to routinely determine gem beryl provenance.

  6. Study of gain variation as a function of physical parameters of GEM foil

    Energy Technology Data Exchange (ETDEWEB)

    Das, Supriya, E-mail: Supriya.Das@cern.ch

    2016-07-11

    The ALICE experiment at LHC has planned to upgrade the TPC by replacing the MWPC with GEM based detecting elements to restrict the IBF to a tolerable value. However the variation of the gain as a function of physical parameters of industrially produced large size GEM foils is needed to be studied as a part of the QA procedure for the detector. The size of the electron avalanche and consequently the gain for GEM based detectors depend on the electric field distribution inside the holes. Geometry of a hole plays an important role in defining the electric field inside it. In this work we have studied the variation of the gain as a function of the hole diameters using Garfield++ simulation package.

  7. Effect of Regrown Graphite on the Growth of Large Gem Diamonds by Temperature Gradient Method

    Institute of Scientific and Technical Information of China (English)

    ZANG Chuan-Yi; JIA Xiao-Peng; MA Hong-An; TIAN Yu; XIAO Hong-Yu

    2005-01-01

    @@ Generally, when growing high-quality large gem diamond crystals by temperature gradient method under high pressure and high temperature, the crystal growth rate is only determined by the temperature gradient. However,we find that the seed crystal cannot completely absorb all the diffused carbon sources, when growing gem diamonds under a higher temperature gradient. Other influence factors appear, and the growth rate of growing diamonds is partly dependent on the crystalline form of superfluous unabsorbed carbon source, flaky regrown graphite or small diamond crystals nucleated spontaneously. The present form is determined by the growth temperature if the pressure isfixed. Different from spontaneous diamond nuclei, the appearance of regrown graphite in the diamondstable region can retard the growth rate of gem diamonds substantially, even if the temperature gradient keeps unchanged. On the other hand, the formation mechanism of metastable regrown graphite in the diamond-stable region is also explained.

  8. Developments and the preliminary tests of Resistive GEMs manufactured by a screen printing technology

    CERN Document Server

    Agócs, G; Oliveira, R; Martinego, P; Peskov, Vladimir; Pietropaolo, P; Picchi, P

    2008-01-01

    We report promising initial results obtained with new resistive-electrode GEM (RETGEM) detectors manufactured, for the first time, using screen printing technology. These new detectors allow one to reach gas gains nearly as high as with ordinary GEM-like detectors with metallic electrodes; however, due to the high resistivity of its electrodes the RETGEM, in contrast to ordinary hole-type detectors, has the advantage of being fully spark protected. We discovered that RETGEMs can operate stably and at high gains in noble gases and in other badly quenched gases, such as mixtures of noble gases with air and in pure air; therefore, a wide range of practical applications, including dosimetry and detection of dangerous gases, is foreseeable. To promote a better understanding of RETGEM technology some comparative studies were completed with metallic-electrode thick GEMs. A primary benefit of these new RETGEMs is that the screen printing technology is easily accessible to many research laboratories. This accessibilit...

  9. A scintillating GEM for 2D-dosimetry in radiation therapy

    CERN Document Server

    Timmer, J; Bom, V; Eijk, C W; Haas, J D; Schippers, J M

    2002-01-01

    The first results of a study on the properties of a gaseous scintillation detector based on a Gas Electron Multiplier (GEM) are reported. The detector is designed for use in position-sensitive dosimetry applications in radiation therapy. A double GEM system, operating in a 90-10% Ar-CO sub 2 gas mixture at a gas amplification factor of approx 3000, emits a sufficient amount of detectable light to perform measurements of approx 1 Gy doses in two dimensions. The light yield does not suffer from quenching processes when particles with high stopping power are detected. This operation mode of GEMs offers the dosimetric advantages of a gas-filled detector and the 2D read-out can be performed with a CCD camera. Compared to the existing dosimeters, this system is relatively simple and no complex multi-electrode read-out is necessary.

  10. A COMSOL-GEMS interface for modeling coupled reactive-transport geochemical processes

    Science.gov (United States)

    Azad, Vahid Jafari; Li, Chang; Verba, Circe; Ideker, Jason H.; Isgor, O. Burkan

    2016-07-01

    An interface was developed between COMSOL MultiphysicsTM finite element analysis software and (geo)chemical modeling platform, GEMS, for the reactive-transport modeling of (geo)chemical processes in variably saturated porous media. The two standalone software packages are managed from the interface that uses a non-iterative operator splitting technique to couple the transport (COMSOL) and reaction (GEMS) processes. The interface allows modeling media with complex chemistry (e.g. cement) using GEMS thermodynamic database formats. Benchmark comparisons show that the developed interface can be used to predict a variety of reactive-transport processes accurately. The full functionality of the interface was demonstrated to model transport processes, governed by extended Nernst-Plank equation, in Class H Portland cement samples in high pressure and temperature autoclaves simulating systems that are used to store captured carbon dioxide (CO2) in geological reservoirs.

  11. The game-based learning evaluation model (GEM): measuring the effectiveness of serious games using a standardised method

    NARCIS (Netherlands)

    Oprins, E.A.P.B.; Visschedijk, G.C.; Bakhuys Roozeboom, M.C.; Dankbaar, M.; Trooster, W.; Schuit, S.C.E.

    2015-01-01

    This article describes the background, design, and practical application of the game-based evaluation model (GEM). The aim of this evaluation model is to measure the effectiveness of serious games in a practical way. GEM contains the methodology and indicators to be measured in validation research.

  12. FPGA-based GEM detector signal acquisition for SXR spectroscopy system

    Science.gov (United States)

    Wojenski, A.; Pozniak, K. T.; Kasprowicz, G.; Kolasinski, P.; Krawczyk, R.; Zabolotny, W.; Chernyshova, M.; Czarski, T.; Malinowski, K.

    2016-11-01

    The presented work is related to the Gas Electron Multiplier (GEM) detector soft X-ray spectroscopy system for tokamak applications. The used GEM detector has one-dimensional, 128 channel readout structure. The channels are connected to the radiation-hard electronics with configurable analog stage and fast ADCs, supporting speeds of 125 MSPS for each channel. The digitalized data is sent directly to the FPGAs using fast serial links. The preprocessing algorithms are implemented in the FPGAs, with the data buffering made in the on-board 2Gb DDR3 memory chips. After the algorithmic stage, the data is sent to the Intel Xeon-based PC for further postprocessing using PCI-Express link Gen 2. For connection of multiple FPGAs, PCI-Express switch 8-to-1 was designed. The whole system can support up to 2048 analog channels. The scope of the work is an FPGA-based implementation of the recorder of the raw signal from GEM detector. Since the system will work in a very challenging environment (neutron radiation, intense electro-magnetic fields), the registered signals from the GEM detector can be corrupted. In the case of the very intense hot plasma radiation (e.g. laser generated plasma), the registered signals can overlap. Therefore, it is valuable to register the raw signals from the GEM detector with high number of events during soft X-ray radiation. The signal analysis will have the direct impact on the implementation of photon energy computation algorithms. As the result, the system will produce energy spectra and topological distribution of soft X-ray radiation. The advanced software was developed in order to perform complex system startup and monitoring of hardware units. Using the array of two one-dimensional GEM detectors it will be possible to perform tomographic reconstruction of plasma impurities radiation in the SXR region.

  13. Magnetic activity and orbital period variation of the eclipsing binary KV Gem

    Science.gov (United States)

    Zhang, Liyun; Pi, Qingfeng; Yang, Yuangui; Li, Zhongmu

    2014-02-01

    This paper presents new CCD BVRI light curves of a neglected eclipsing binary KV Gem. Our new light curves were obtained in 2010 and 2011 at the Xinglong station of the National Astronomical Observatories, China. By analyzing all available light minimum times, we derived an update ephemeris and found there existed a cyclic variation overlaying a continuous period decrease. This kind of cyclic variation may probably be attributed to the light-time effect via the presence of an unseen third body or magnetic activity cycle. The long-term period decrease suggests that KV Gem is undergoing a mass transfer from the secondary component to the primary component at a rate of 3.4(0.3)×(10-7 M⊙/year for period decrease and a third body (10.3±0.2 years), and 5.5(0.6)×10-7 M⊙/year for decrease and magnetic cycle (8.8±0.1 years). By analyzing the light curves in 2011, photometric solutions and starspots parameters of the system are obtained using Wilson-Devinney program. Based on the photometric solution in 2011, we still could use the spot model to explain successfully our light curves in 2010 and three published light curves. Comparing the starspot longitudes and factors, KV Gem are variable on a long time scale of about years. For the data of KV Gem, the brightness vary with time around phases 0, 0.25, 0.5, and 0.75, which means that there is a possible photospheric active evolution. More data are needed to monitor to detect stellar cycle of KV Gem. For chromospheric activity of KV Gem, we found strong absorption in the observed Hβ,Hγ, and Ca II H & K spectra, and no obvious emission.

  14. Advances in Trace Element “Fingerprinting” of Gem Corundum, Ruby and Sapphire, Mogok Area, Myanmar

    Directory of Open Access Journals (Sweden)

    F. Lin Sutherland

    2014-12-01

    Full Text Available Mogok gem corundum samples from twelve localities were analyzed for trace element signatures (LA-ICP-MS method and oxygen isotope values (δ18O, by laser fluorination. The study augmented earlier findings on Mogok gem suites that suggested the Mogok tract forms a high vanadium gem corundum area and also identified rare alluvial ruby and sapphire grains characterised by unusually high silicon, calcium and gallium, presence of noticeable boron, tin and niobium and very low iron, titanium and magnesium contents. Oxygen isotope values (δ18O for the ruby and high Si-Ca-Ga corundum (20‰–25‰ and for sapphire (10‰–20‰ indicate typical crustal values, with values >20‰ being typical of carbonate genesis. The high Si-Ca-Ga ruby has high chromium (up to 3.2 wt % Cr and gallium (up to 0. 08 wt % Ga compared to most Mogok ruby (<2 wt % Cr; <0.02 wt % Ga. In trace element ratio plots the Si-Ca-Ga-rich corundum falls into separate fields from the typical Mogok metamorphic fields. The high Ga/Mg ratios (46–521 lie well within the magmatic range (>6, and with other features suggest a potential skarn-like, carbonate-related genesis with a high degree of magmatic fluid input The overall trace element results widen the range of different signatures identified within Mogok gem corundum suites and indicate complex genesis. The expanded geochemical platform, related to a variety of metamorphic, metasomatic and magmatic sources, now provides a wider base for geographic typing of Mogok gem corundum suites. It allows more detailed comparisons with suites from other deposits and will assist identification of Mogok gem corundum sources used in jewelry.

  15. Construction of a Gas Electron Multiplier (GEM) Detector for Medical Imaging

    OpenAIRE

    2013-01-01

    A prototype Gas Electron Multiplier (GEM) detector is under construction for medical imaging purposes. A single thick GEM of size 10x10 cm^2 is assembled inside a square shaped air-tight box which is made of Perspex glass. In order to ionize gas inside the drift field two types of voltage supplier circuits were fabricated, and array of 2x4 pads of each size 4x8 mm^2 were utilized for collecting avalanche charges. Preliminary testing results show that the circuit which produces high voltage an...

  16. Proceso de creación de Almus-Gemüse: pates de legumbres

    OpenAIRE

    MATA CAGIGAO, ELENA

    2016-01-01

    [ES] Almus-Gemüse es proyecto de diseño de producto enmarcado en un proyecto empresarial presentado al certamen nacional Ecotrophelia 2016. Con él los alumnos implicados consiguieron el tercer puesto. Almus-Gemüse está enfocado a la elaboración de productos con textura de paté, con altramuces como ingrediente base. El proyecto propone una gamma de productos sabores del mundo creados con diferentes especias e ingredientes. Para el desarrollo de este proyecto se emplearon las cinco pa...

  17. Quality assurance of GEM foils in the framework of the TPC upgrade in the ALICE experiment

    CERN Document Server

    Ozcelik, Melih Arslan

    2016-01-01

    In the framework of the TPC upgrade of the ALICE Experiment, new readout chambers will be installed during the LHC long shutdown 2, which is scheduled to start in July 2018. The current MWPCs (Multi Wire Proportional Chambers) will be replaced by readout chambers consisting of GEM (Gas Electron Multipliers) foils in order to meet the increasing readout rate requirements. QA (Quality Assurance) tests on the GEMs are performed to classify the foils. In this report we present the work done during the CERN Summer Student Programme 2016.

  18. The analysis of SuperWASP photometric data for the overcontact binary QW Gem

    Directory of Open Access Journals (Sweden)

    Cséki A.

    2013-01-01

    Full Text Available The paper presents an analysis of photometric observations of the eclipsing binary QW Gem. The orbital and physical parameters of the system are derived using the modeling code by G. Djurašević. Photometric observations are obtained from the SuperWASP public archive and the spectroscopic elements are adopted from a recently published radial velocity study. The results suggest that QW Gem is a binary in overcontact configuration, consisting of two stars of similar surface brightness but in different evolutionary stages.

  19. GEM tracker for high luminosity experiments at the JLab Hall A

    Energy Technology Data Exchange (ETDEWEB)

    Bellini, Vincenzo G; Cisbani, Evaristo; Capogni, Marco; Colilli, Stephano P; De Leo, Raffaele A; De Oliveira, Denny M; De Smet, Fabienne; Fratoni, Rolando; Frullani, Salvatore; Giuliani, Fausto; Gricia, Massimo; Librizzi, F; Maurizio, Lucentini; Mammoliti, Francesco D; Minutoli, Saverio G; Musico, Paolo; Noto, Francesco; Perrino, Roberto; Santavenere, Fabio; Sutera, Concetta

    2012-05-01

    A new large-area, lightweight tracker based on the GEM technology is under development for the upcoming experiments in Hall A at Jefferson Lab, where a longitudinally polarized electron beam of 11 GeV will be available in late 2013. This beam, combined with innovative polarized targets, will provide luminosity up to 10{sup 39}/(s-cm{sup 2}) opening exciting opportunities to investigate unexplored aspects of the inner structure of the nucleon and the dynamics of its constituents. The GEM tracker design is presented in this paper.

  20. Divergent Mechanistic Routes for the Formation of gem-Dimethyl Groups in the Biosynthesis of Complex Polyketides

    Energy Technology Data Exchange (ETDEWEB)

    Poust, S; Phelan, RM; Deng, K; Katz, L; Petzold, CJ; Keasling, JD

    2015-01-07

    The gem-dimethyl groups in polyketide-derived natural products add steric bulk and, accordingly, lend increased stability to medicinal compounds, however, our ability to rationally incorporate this functional group in modified natural products is limited. In order to characterize the mechanism of gem-dimethyl group formation, with a goal toward engineering of novel compounds containing this moiety, the gem-dimethyl group producing polyketide synthase (PKS) modules of yersiniabactin and epothilone were characterized using mass spectrometry. The work demonstrated, contrary to the canonical understanding of reaction order in PKSs, that methylation can precede condensation in gem-dimethyl group producing PKS modules. Experiments showed that both PKSs are able to use dimethylmalonyl acyl carrier protein (ACP) as an extender unit. Interestingly, for epothilone module8, use of dimethylmalonyl-ACP appeared to be the sole route to form a gem-dimethylated product, while the yersiniabactin PKS could methylate before or after ketosynthase condensation.

  1. MIT Mints a Valuable New Form of Academic Currency

    Science.gov (United States)

    Carey, Kevin

    2012-01-01

    The Massachusetts Institute of Technology (MIT) has invented or improved many world-changing things--radar, information theory, and synthetic self-replicating molecules, to name a few. Last month the university announced, to mild fanfare, an invention that could be similarly transformative, this time for higher education itself. It is called MITx.…

  2. Interaktion mit RFID Ausleih- und Rückgabeautomaten

    DEFF Research Database (Denmark)

    Greifeneder, Elke; Heyroth, Melanie; Klingbeil, Karin

    2011-01-01

    Der Artikel untersucht mittels Beobachtung die Interaktion zwischen RFID-Ausleih- und Rückgabeautomaten sowie Bibliotheksbenutzern in vier deutschen Bibliotheken. Die Ergebnisse belegen, dass die Interaktion grundsätzlich funktioniert. Die Benutzer zeigten Gelassenheit und Routine im Umgang mit den...

  3. MIT Laboratory for Computer Science Progress Report 27

    Science.gov (United States)

    1990-06-01

    C. Waldspurger B. Gates M. Williams Undergraduate Students M. Levine A. Rhee V. Nicotina M. Sexton C. Poelman R. Stata Support Staff A. Rubin 113...Science, May 1990. [5] V. Nicotina . Implementing Mobile Guardians in Argus. Bachelor’s thesis, MIT Department of Electrical Engineering and Computer Science

  4. Numerische Berechnung von Wirbelstromproblemen mit der Cell-Methode

    Directory of Open Access Journals (Sweden)

    K. Frenner

    2006-01-01

    Full Text Available In dieser Arbeit wird die Cell-Methode auf die quasistatischen Maxwellgleichungen angewendet. Dabei werden für die notwendige Transformation vom Primärgitter auf das duale Gitter reziproke Basisvektoren verwendet. Anhand der Felddiffusion der magnetischen Induktion in einen zylindrischen Leiter werden Ergebnisse der Cell-Methode mit einer analytischen Vergleichsrechnung präsentiert.

  5. Wie ich mich mit dem äthiopischen Regime anlegte

    DEFF Research Database (Denmark)

    Hagmann, Tobias

    2016-01-01

    Als Forscher und Kritiker der äthiopischen Politik habe ich viel über das Verhältnis gelernt, in dem Wahrheit und Macht, aber auch Moral und persönliche Interessen zueinander stehen. In den Niederungen der Realpolitik wird mit harten Bandagen um die Deutungshoheit gekämpft wird. Auch Wissenschafter...

  6. The GEM code. A simulation program for the evaporation and the fission process of an excited nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Furihata, Shiori [Mitsubishi Research Institute Inc., Tokyo (Japan); Niita, Koji [Research Organization for Information Science and Technology, Tokai, Ibaraki (Japan); Meigo, Shin-ichiro; Ikeda, Yujiro; Maekawa, Fujio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-03-01

    The GEM code is a simulation program which describes the de-excitation process of an excited nucleus, which is based on the Generalized Evaporation Model and the Atchison fission model. It has been shown that the combination of the Bertini intranuclear cascade model and GEM accurately predicts the cross sections of light fragments, such as Be produced from the proton-induced reactions. It has also been shown that the use of the reevaluated parameters in the Atchison model improves predictions of cross sections of fission fragments produced from the proton-induced reaction on Au. In this report, we present details and the usage of the GEM code. Furthermore, the results of benchmark calculations are shown by using the combination of the Bertini intranuclear cascade model and the GEM code (INC/GEM). Neutron spectra and isotope production cross sections from the reactions on various targets irradiated by protons are calculated with INC/GEM. Those results are compared with experimental data as well as the calculation results with LAHET. INC/GEM reproduces the experiments of double differential neutron emissions from the reaction on Al and Pb. The isotopic distributions for He, Li, and Be produced from the reaction on Ag are in good agreement with experimental data within 50%, although INC/GEM underestimates those of heavier nuclei than O. It is also shown that the predictions with INC/GEM for isotope production of light fragments, such as Li and Be, are better than those calculation with LAHET, particularly for heavy target. INC/GEM also gives better estimates of the cross sections of fission products than LAHET. (author)

  7. Establishment and biological characteristics of a multi-drug resistant cell line A549/Gem

    Directory of Open Access Journals (Sweden)

    Yunfeng ZHU

    2008-02-01

    Full Text Available Background and objective Multi-drug resistance is one of the most important reason why the survival time of non-small cell lung cancer patients is so short. The aim of this study is to establish multi-drug resistant cell line A549/Gem and discuss its biological characters so as to elaborate the possible mechanisms of gemcitabine resistance. Methods Human gemcitabine-resistant non-small cell lung cancer cell line A549/Gem was established by repeated clinical serous peak concentration then low but gradually increasing concentration of gemcitabine from its parental cell human lung adenocarcinoma cell line A549 which is sensitive to gemcitabine. During the course of inducement, monitored its morphology, checked its resistance index and resistant pedigree by MTT method, gathered its growth curve and calculated its doubling time, examined its DNA contents and cell cycles by flow cytometry; at the same time, measured its expression of P53, EGFR, c-erb-B-2, PTEN, PCNA, c-myc, VEGF, MDR-1, Bcl-2, nm23, MMP-9, TIMP-1, CD44v6 Proteins, and RRM1 mRNA. Results The resistance index of A549/Gem?to gemcitabine was 163.228, and the cell line also exhibited cross-resistance to vinorelbine, taxotere, fluorouraci, etoposide and cisplatin, but kept sensitivity to paclitaxol and oxaliplatin. The doubling time of it was shorter and figures in G0-G1 phase were increased than A549. Compared with A549, A549/Gem?achieved EGFR and c-myc protein expression, nm23 protein expression enhanced, p53, Cerb-B-2 and bcl-2 protein expression reduced, PTEN, PCNA and MDR-1 protein expression vanished, but that of MMP-9, VEGF, CD44v6 and TIMP-1 protein changed trivially. Meanwhile, the expression of RRM1 mRNA was augmented markedly. The resistance index of A549/Gem to gemcitabine was 129.783, and the cell line also held cross-resistance to vinorelbine, taxotere, etoposide, cisplatin and sensitivity to paclitaxol. But the resistance to fluorouracil and sensitivity to oxaliplatin

  8. OpenGeoSys-GEMS: Hybrid parallelization of a reactive transport code with MPI and threads

    Science.gov (United States)

    Kosakowski, G.; Kulik, D. A.; Shao, H.

    2012-04-01

    OpenGeoSys-GEMS is a generic purpose reactive transport code based on the operator splitting approach. The code couples the Finite-Element groundwater flow and multi-species transport modules of the OpenGeoSys (OGS) project (http://www.ufz.de/index.php?en=18345) with the GEM-Selektor research package to model thermodynamic equilibrium of aquatic (geo)chemical systems utilizing the Gibbs Energy Minimization approach (http://gems.web.psi.ch/). The combination of OGS and the GEM-Selektor kernel (GEMS3K) is highly flexible due to the object-oriented modular code structures and the well defined (memory based) data exchange modules. Like other reactive transport codes, the practical applicability of OGS-GEMS is often hampered by the long calculation time and large memory requirements. • For realistic geochemical systems which might include dozens of mineral phases and several (non-ideal) solid solutions the time needed to solve the chemical system with GEMS3K may increase exceptionally. • The codes are coupled in a sequential non-iterative loop. In order to keep the accuracy, the time step size is restricted. In combination with a fine spatial discretization the time step size may become very small which increases calculation times drastically even for small 1D problems. • The current version of OGS is not optimized for memory use and the MPI version of OGS does not distribute data between nodes. Even for moderately small 2D problems the number of MPI processes that fit into memory of up-to-date workstations or HPC hardware is limited. One strategy to overcome the above mentioned restrictions of OGS-GEMS is to parallelize the coupled code. For OGS a parallelized version already exists. It is based on a domain decomposition method implemented with MPI and provides a parallel solver for fluid and mass transport processes. In the coupled code, after solving fluid flow and solute transport, geochemical calculations are done in form of a central loop over all finite

  9. Parallelization experience with four canonical econometric models using ParMitISEM

    NARCIS (Netherlands)

    Baştürk, N.; Grassi, S.; Hoogerheide, L.; van Dijk, H.K.

    2016-01-01

    This paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm, introduced by Hoogerheide et al. (2012), provides an automatic and flexible method to approximate a non-elliptical target density using adaptive mixtures of Stud

  10. Validation of neutron texture data on GEM at ISIS using electron backscattered diffraction

    Science.gov (United States)

    Davies, Peter; Kockelmann, Winfried; Wynne, Brad; Eccleston, Roger; Hutchinson, Bevis; Rainforth, W. Mark

    2008-03-01

    The high solid angular coverage of the general materials (GEM) diffractometer at the ISIS pulsed neutron source located at the UK Rutherford Appleton Laboratory offers the capability of obtaining quantitative bulk crystallographic texture data in a 'single shot' within a matter of minutes. This enables the possibility of in situ texture measurements to be made as a function of temperature to monitor and quantify texture changes during phase transformation or microstructure restoration processes like recrystallization. The purpose of this paper is to determine the quality of the texture data produced from GEM in order to define a level of confidence for subsequent texture model validation. This has been achieved by comparing textures of sections of a 200 mm diameter titanium alloy billet using data obtained from GEM with data obtained using electron backscattered diffraction (EBSD). In both cases, the data were obtained at room temperature. EBSD, unlike time-of-flight neutron diffraction analysis, obtains texture data directly from orientation measurements via backscattered Kikuchi patterns in the scanning electron microscope. In all analysed locations, both methods show near-identical textures, with regard to both the general orientation distributions and the levels of intensity of the distributions. This shows that the GEM diffractometer is capable of accurately determining bulk textures in a single shot, thus confirming its suitability for in situ high temperature experiments.

  11. Differentiation of diastereotopic bromine atoms in SN2 reactions of gem-dibromides.

    Science.gov (United States)

    Münster, Niels; Harms, Klaus; Koert, Ulrich

    2012-02-11

    A novel directed S(N)2 reaction of conformationally biased gem-dibromides and an arenesulfinate anion is described. The reaction results in the diastereoselective formation of α-bromosulfones. The selectivity originates from pre-coordination of the nucleophile to a free hydroxyl group in the γ-position.

  12. Microstructured boron foil scintillating G-GEM detector for neutron imaging

    Science.gov (United States)

    Fujiwara, Takeshi; Bautista, Unico; Mitsuya, Yuki; Takahashi, Hiroyuki; Yamada, Norifumi L.; Otake, Yoshie; Taketani, Atsushi; Uesaka, Mitsuru; Toyokawa, Hiroyuki

    2016-12-01

    In this study, a new simple neutron imaging gaseous detector was successfully developed by combining a micro-structured 10B foil, a glass gas electron multiplier (G-GEM), and a mirror-lens-charge-coupled device (CCD)-camera system. The neutron imaging system consists of a chamber filled with Ar/CF4 scintillating gas mixture. Inside this system, the G-GEM is mounted for gas multiplication. The neutron detection in this system is based on the reaction between 10B and neutrons. A micro-structured 10B is developed to overcome the issue of low detection efficiency. Secondary electrons excite Ar/CF4 gas molecules, and high-yield visible photons are emitted from those excited gas molecules during the gas electron multiplication process in the G-GEM holes. These photons are easily detected by a mirror-lens-CCD-camera system. A neutron radiograph is then simply formed. We obtain the neutron images of different materials with a compact accelerator-driven neutron source. We confirm that the new scintillating G-GEM-based neutron imager works properly with low gamma ray sensitivity and exhibits a good performance as a new simple digital neutron imaging device.

  13. Promoting microbiology education through the iGEM synthetic biology competition.

    Science.gov (United States)

    Kelwick, Richard; Bowater, Laura; Yeoman, Kay H; Bowater, Richard P

    2015-08-01

    Synthetic biology has developed rapidly in the 21st century. It covers a range of scientific disciplines that incorporate principles from engineering to take advantage of and improve biological systems, often applied to specific problems. Methods important in this subject area include the systematic design and testing of biological systems and, here, we describe how synthetic biology projects frequently develop microbiology skills and education. Synthetic biology research has huge potential in biotechnology and medicine, which brings important ethical and moral issues to address, offering learning opportunities about the wider impact of microbiological research. Synthetic biology projects have developed into wide-ranging training and educational experiences through iGEM, the International Genetically Engineered Machines competition. Elements of the competition are judged against specific criteria and teams can win medals and prizes across several categories. Collaboration is an important element of iGEM, and all DNA constructs synthesized by iGEM teams are made available to all researchers through the Registry for Standard Biological Parts. An overview of microbiological developments in the iGEM competition is provided. This review is targeted at educators that focus on microbiology and synthetic biology, but will also be of value to undergraduate and postgraduate students with an interest in this exciting subject area.

  14. Experiential Engineering through iGEM--An Undergraduate Summer Competition in Synthetic Biology

    Science.gov (United States)

    Mitchell, Rudolph; Dori, Yehudit Judy; Kuldell, Natalie H.

    2011-01-01

    Unlike students in other engineering disciplines, undergraduates in biological engineering typically have limited opportunity to develop design competencies, and even fewer chances to implement their designed projects. The international Genetically Engineered Machines (iGEM) competition is a student Synthetic Biology competition that, in 2009,…

  15. LHCb: A fast triple-GEM detector for high-rate charged-particle triggering

    CERN Multimedia

    2001-01-01

    - GEM: Principle of Operation - Time Performances - Detector Prototypes and Test Setup - Gas Mixtures - Fields Optimisation - Vgem Optimisation Ar/CO2 (70/30) - Vgem Optimisation Ar/CO2/CF4 (60/20/20) - Time Distributions - Future Tests and Developments

  16. Development and Test of a GEM-Based TEPC System for In-Phantom Dose Measurements

    Energy Technology Data Exchange (ETDEWEB)

    C-K Chris Wang

    2007-03-13

    The objectives of this project include: (1) to construct a minature tissue equivalent proportional counter (TEPC) using a gas-electron-multiplier (GEM) foil, and (2) to conduct neutron and gamma-ray dose measurements with the detector embedded in a phantom

  17. Evaluation of the GEM-AQ model in the context of the AQMEII Phase 1 project

    Directory of Open Access Journals (Sweden)

    J. Struzewska

    2015-01-01

    Full Text Available In the scope of the AQMEII Phase 1 project the GEM-AQ model was run over Europe for the year 2006. The modelling domain was defined using a global variable resolution grid with a rotated equator and uniform resolution of 0.2° × 0.2° over the European continent. Spatial distribution and temporal variability of the GEM-AQ model results were analysed for surface ozone and PM10 concentrations. Model results were compared with measurements available in the ENSEMBLE database. Statistical measures were used to evaluate performance of the GEM-AQ model. The mean bias error, the mean absolute gross error and the Pearson correlation coefficient were calculated for the maximum 8 h running average ozone concentrations and daily mean PM10 concentrations. The GEM-AQ model performance was characterised for station types, European climatic regions, and seasons. The best performance for ozone was obtained at suburban stations and the worst performance was obtained for rural stations where the model tends to underestimate. The best results for PM10 were calculated for urban stations, while over most of Europe concentrations at rural sites were too high. Discrepancies between modelled and observed concentrations were discussed in the context of emission data uncertainty as well as the impact of large scale dynamics and circulation of air masses. Presented analyses suggest that interpretation of modelling results is enhanced when regional climate characteristics are ta ken into consideration.

  18. X-ray imaging with GEMs using $100\\,\\mu$m thick foils

    CERN Document Server

    da Luz, H Natal; Carvalho, X; Santos, J M F dos

    2013-01-01

    A simple X-ray imaging system using off-the-shelf electronics and simple reconstruction algorithms aiming a spatial resolution of 1.7 mm ($\\sim 3%$ of the detector length) is described in this work. For this, two 100 cm$^2$ Gas Electron Multiplier (GEM) foils with a thickness of $100\\,\\mu$m (2-fold thicker than the standard ones) were immersed in a mixture of argon and carbon dioxide (70:30). The charge readout with 2D position determination was done with resistive charge division. Thicker foils reach higher electron multiplication than the standard GEM, easily reaching charge gains in excess of 10$^4$, when operated in a double GEM cascade configuration. Furthermore, the $100 \\mu$m thick GEM foils were found to be less prone to damage caused by electrical discharges. X-ray images are shown and some descriptions of the physical processes involved are presented. We describe the advantages of this method that allows counting each X-ray photon or particle entering the detector, its interaction position, as well ...

  19. Data Quality Monitoring System for New GEM Muon Detectors for the CMS Experiment Upgrade

    Science.gov (United States)

    King, Robert; CMS Muon group Team

    2017-01-01

    The Gas Electron Multiplier (GEM) detectors are novel detectors designed to improve the muon trigger and tracking performance in CMS experiment for the high luminosity upgrade of the LHC. Partial installation of GEM detectors is planned during the 2016-2017 technical stop. Before the GEM system is installed underground, its data acquisition (DAQ) electronics must be thoroughly tested. The DAQ system includes several commercial and custom-built electronic boards running custom firmware. The front-end electronics are radiation-hard and communicate via optical fibers. The data quality monitoring (DQM) software framework has been designed to provide online verification of the integrity of the data produced by the detector electronics, and to promptly identify potential hardware or firmware malfunctions in the system. Local hits reconstruction and clustering algorithms allow quality control of the data produced by each GEM chamber. Once the new detectors are installed, the DQM will monitor the stability and performance of the system during normal data-taking operations. We discuss the design of the DQM system, the software being developed to read out and process the detector data, and the methods used to identify and report hardware and firmware malfunctions of the system.

  20. MeerLICHT and BlackGEM: custom-built telescopes to detect faint optical transients

    Science.gov (United States)

    Bloemen, Steven; Groot, Paul; Woudt, Patrick; Klein Wolt, Marc; McBride, Vanessa; Nelemans, Gijs; Körding, Elmar; Pretorius, Margaretha L.; Roelfsema, Ronald; Bettonvil, Felix; Balster, Harry; Bakker, Roy; Dolron, Peter; van Elteren, Arjen; Elswijk, Eddy; Engels, Arno; Fender, Rob; Fokker, Marc; de Haan, Menno; Hagoort, Klaas; de Hoog, Jasper; ter Horst, Rik; van der Kevie, Giel; Kozłowski, Stanisław; Kragt, Jan; Lech, Grzegorz; Le Poole, Rudolf; Lesman, Dirk; Morren, Johan; Navarro, Ramon; Paalberends, Willem-Jelle; Paterson, Kerry; Pawłaszek, Rafal; Pessemier, Wim; Raskin, Gert; Rutten, Harrie; Scheers, Bart; Schuil, Menno; Sybilski, Piotr W.

    2016-07-01

    We present the MeerLICHT and BlackGEM telescopes, which are wide-field optical telescopes that are currently being built to study transient phenomena, gravitational wave counterparts and variable stars. The telescopes have 65 cm primary mirrors and a 2.7 square degree field-of-view. The MeerLICHT and BlackGEM projects have different science goals, but will use identical telescopes. The first telescope, MeerLICHT, will be commissioned at Sutherland (South Africa) in the first quarter of 2017. It will co-point with MeerKAT to collect optical data commensurate with the radio observations. After careful analysis of MeerLICHT's performance, three telescopes of the same type will be commissioned in La Silla (Chile) in 2018 to form phase I of the BlackGEM array. BlackGEM aims at detecting and characterizing optical counterparts of gravitational wave events detected by Advanced LIGO and Virgo. In this contribution we present an overview of the science goals, the design and the status of the two projects.

  1. Multicolor photometry of SU UMa and U Gem during quiescence, outburst and superoutburst

    CERN Document Server

    Wychudzki, P; Wiecek, M; Karska, A; Galan, C; Swierczynski, E; Frackowiak, S; Tomov, T

    2010-01-01

    The results of time-resolved observations of SU UMa and U Gem obtained over two-years are presented. Both stars are prototypes of different classes of dwarf novae. We studied brightness variations on different time scales: orbital, QPO and flickering. The multicolor BVRI photometry allows to distinguisch the geometrical and physical sources of these variations.

  2. Physics motivations and expected performance of the CMS muon system upgrade with triple-GEM detectors

    CERN Document Server

    Venditti, Rosamaria; Abbrescia, Marcello; Aleksandrov, Andrey B; Benussi, Luigi; Beni, Noemi; Bianco, Stefano; Calabria, Cesare; Caponero, Michele; Hernandez, Alfredo Martin Castaneda; Cavallo, Francesca; Colafranceschi, Stefano; Lentdecker, Gilles De; Oliveira, R; Guiducci, Luigi; Hoepfner, Kerstin; Iaydjiev, P S; Korytov, Andrey; Krutelyov, Slava; Kumar, A; Lee, Jason; Litov, L; Loddo, F; Maggi, M; Marchioro, Alessandro; Mitselmakher, Guenakh; Mohanty, Ajit Kumar; Molnar, J; Naimuddin, Md; Nuzzo, S; Pant, Lalit; Paolucci, Pierluigi; Pavlov, Borislav; Piccolo, Davide; Postema, Hans; Raffaella, Radogna; Ranieri, A; Riccardi, C; Rodozov, Mircho; Safonov, Alexei; Saviano, Giovanna; Sharma, Archana; Tytgat, Michael; Vitulo, Paolo; Colaleo, Anna; Caputo, Claudio; Errico, Filippo; Dildick, Sven; Vai, Ilaria; Magnani, Alice; Verwilligen, Piet; Altieri, Palma; Aspell, Paul; Giacomelli, Paolo; Braibant, Sylvie; Buontempo, S; Kamon, Teruki; Tatarinov, A; Celik, Ali; Gilmore, Jason; Flanagan, Will; Khotilovich, Vadim; Czellar, S; Fenyvesi, A; Jozsef Molnar@Cern Ch, Jozsef; Barria, P; Korntheuer, Michael; Lenzi, T; Maerschalk, T; Verhagen, E; Yang, Yifan; Yonamine, R; Zenoni, F; Merlin, J; Dorney, B; Garcia, A Conde; Dabrowski, M; Marinov, A; Oliveri, E; Baranac, A Puig; Ropelewski, Leszek; Bos, J; Bally, S; Stenis, M Van; Ferry, S; Rodrigues, A; Robertis, G De; Christiansen, J; Hohlmann, M; Bhopatkar, V; Mohapatra, A; Zhang, A; Hauser, J; Tuuva, Tuure; Talvitie, J; Passeggio, G; Cassese, F; Banerjee, S; Majumdar, N; Mukhopadhyay, Supratik; Roychowdhur, S; Salva, S; Zaganidis, N; Cimmino, A; Cauwenbergh, S; Bouhali, O; Akl, M Abi; Sturdy, J; Karchin, P; Gutierrez, A; Hadjiiska, R; Aleksandrov, Aleksandar; Rashevski, G; Rodozov, M; Shopova, M; Sultanov, G; Acosta, D; Barashko, V; Furic, I; Madorsky, A; Korytov, A; Mitselmakher, G; Raffone, G; Radi, A; Assran, Y; Aboamer, O; Ahmad, A; Ahmed, W; Awan, I; Hoorani, H; Muhammad, S; Sharma, R; Geonmo, R; Ryu, M S; Park, I; Jeng, Y C; Choi, M; Golovtsov, V; Volkov, S; Vorobyev, A; Choi, S; Guilloux, F; Philipps, B

    2015-01-01

    For the LHC High Luminosity phase (HL-LHC) the CMS GEM Collaboration is planning to in- stall new large size triple-GEM detectors in the forward region of the muon system (1.5< j h |<2.2) of the CMS detector. The muon reconstruction with triple-GEM chambers information included have been successfully integrated in the official CMS software, allowing physics studies to be carried out. The new sub-detector will be able to cope the extreme particle rates expected in this region along with a high spatial resolution. The resulting benefit in terms of triggering and tracking capabilities has been studied: the expected improvement in the performance of the muon identification and track reconstruction as well as the expected improvement coming from the low- ering of the muon p T trigger tresholds will be presented. The contribution will review the status of the CMS upgrade project with the usage of GEM detector, discussing the trigger, the muon reconstruction performance and the impact on the physics analyses.

  3. hpGEM -- A software framework for discontinuous Galerkin finite element methods

    NARCIS (Netherlands)

    Pesch, L.; Bell, A.; Sollie, W.E.H.; Ambati, V.R.; Bokhove, O.; Vegt, van der J.J.W.

    2007-01-01

    hpGEM, a novel framework for the implementation of discontinuous Galerkin finite element methods (FEMs), is described. We present data structures and methods that are common for many (discontinuous) FEMs and show how we have implemented the components as an object-oriented framework. This framework

  4. hpGEM -- A software framework for discontinuous Galerkin finite element methods

    NARCIS (Netherlands)

    Pesch, L.; Bell, A.; Sollie, W.E.H.; Ambati, V.R.; Bokhove, O.; Vegt, van der J.J.W.

    2006-01-01

    hpGEM, a novel framework for the implementation of discontinuous Galerkin finite element methods, is described. We present structures and methods that are common for many (discontinuous) finite element methods and show how we have implemented the components as an object-oriented framework. This fra

  5. Application of CMOS charge-sensitive preamplifier in triple-GEM detector

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Among the various micro-pattern gas detectors (MPGD) that are available, the gas electron multiplier (GEM) detector is an attractive gas detector that has been used in particle physics experiments. However the GEM detector usually needs thousands of preamplifier units for its large number of micro-pattern readout strips or pads,which leads to considerable difficulties and complexities for front end electronics (FEE). Nowadays, by making use of complementary metal-oxide semiconductor (CMOS)-based application specific integrated circuit (ASIC), it is feasible to integrate hundreds of preamplifier units and other signal process circuits in a small-sized chip, which can be bound to the readout strips or pads of a micro-pattern particle detector (MPPD). Therefore, CMOS ASIC may provide an ideal solution to the readout problem of MPPD. In this article, a triple GEM detector is constructed and one of its readout strips is connected to a CMOS charge-sensitive preamplifier chip. The chip was exposed to an 55Fe source of 5.9 keV X-ray, and the amplitude spectrum of the chip was tested, and it was found that the energy resolution was approximately 27%, which indicates that the chip can be used in triple GEM detectors.

  6. A geopotential model from satellite tracking, altimeter, and surface gravity data: GEM-T3

    Science.gov (United States)

    Lerch, F. J.; Nerem, R. S.; Putney, B. H.; Felsentreger, T. L.; Sanchez, B. V.; Marshall, J. A.; Klosko, S. M.; Patel, G. B.; Williamson, R. G.; Chinn, D. S.

    1994-01-01

    An improved model of Earth's gravitational field, Goddard Earth Model T-3 (GEM-T3), has been developed from a combination of satellite tracking, satellite altimeter, and surface gravimetric data. GEM-T3 provides a significant improvement in the modeling of the gravity field at half wavelengths of 400 km and longer. This model, complete to degree and order 50, yields more accurate satellite orbits and an improved geoid representation than previous Goddard Earth Models. GEM-T3 uses altimeter data from GEOS 3 (1975-1976), Seasat (1978) and Geosat (1986-1987). Tracking information used in the solution includes more than 1300 arcs of data encompassing 31 different satellites. The recovery of the long-wavelength components of the solution relies mostly on highly precise satellite laser ranging (SLR) data, but also includes Tracking Network (TRANET) Doppler, optical, and satellite-to-satellite tracking acquired between the ATS 6 and GEOS 3 satellites. The main advances over GEM-T2 (beyond the inclusion of altimeter and surface gravity information which is essential for the resolution of the shorter wavelength geoid) are some improved tracking data analysis approaches and additional SLR data. Although the use of altimeter data has greatly enhanced the modeling of the ocean geoid between 65 deg N and 60 deg S latitudes in GEM-T3, the lack of accurate detailed surface gravimetry leaves poor geoid resolution over many continental regions of great tectonic interest (e.g., Himalayas, Andes). Estimates of polar motion, tracking station coordinates, and long-wavelength ocean tidal terms were also made (accounting for 6330 parameters). GEM-T3 has undergone error calibration using a technique based on subset solutions to produce reliable error estimates. The calibration is based on the condition that the expected mean square deviation of a subset gravity solution from the full set values is predicted by the solutions' error covariances. Data weights are iteratively adjusted until

  7. Open source large-scale high-resolution environmental modelling with GEMS

    Science.gov (United States)

    Baarsma, Rein; Alberti, Koko; Marra, Wouter; Karssenberg, Derek

    2016-04-01

    Many environmental, topographic and climate data sets are freely available at a global scale, creating the opportunities to run environmental models for every location on Earth. Collection of the data necessary to do this and the consequent conversion into a useful format is very demanding however, not to mention the computational demand of a model itself. We developed GEMS (Global Environmental Modelling System), an online application to run environmental models on various scales directly in your browser and share the results with other researchers. GEMS is open-source and uses open-source platforms including Flask, Leaflet, GDAL, MapServer and the PCRaster-Python modelling framework to process spatio-temporal models in real time. With GEMS, users can write, run, and visualize the results of dynamic PCRaster-Python models in a browser. GEMS uses freely available global data to feed the models, and automatically converts the data to the relevant model extent and data format. Currently available data includes the SRTM elevation model, a selection of monthly vegetation data from MODIS, land use classifications from GlobCover, historical climate data from WorldClim, HWSD soil information from WorldGrids, population density from SEDAC and near real-time weather forecasts, most with a ±100m resolution. Furthermore, users can add other or their own datasets using a web coverage service or a custom data provider script. With easy access to a wide range of base datasets and without the data preparation that is usually necessary to run environmental models, building and running a model becomes a matter hours. Furthermore, it is easy to share the resulting maps, timeseries data or model scenarios with other researchers through a web mapping service (WMS). GEMS can be used to provide open access to model results. Additionally, environmental models in GEMS can be employed by users with no extensive experience with writing code, which is for example valuable for using models

  8. The GTPase Gem and its partner Kif9 are required for chromosome alignment, spindle length control, and mitotic progression.

    Science.gov (United States)

    Andrieu, Guillaume; Quaranta, Muriel; Leprince, Corinne; Hatzoglou, Anastassia

    2012-12-01

    Within the Ras superfamily, Gem is a small GTP-binding protein that plays a role in regulating Ca(2+) channels and cytoskeletal remodeling in interphase cells. Here, we report for the first time that Gem is a spindle-associated protein and is required for proper mitotic progression. Functionally, loss of Gem leads to misaligned chromosomes and prometaphase delay. On the basis of different experimental approaches, we demonstrate that loss of Gem by RNA interference induces spindle elongation, while its enforced expression results in spindle shortening. The spindle length phenotype is generated through deregulation of spindle dynamics on Gem depletion and requires the expression of its downstream effector, the kinesin Kif9. Loss of Kif9 induces spindle abnormalities similar to those observed when Gem expression is repressed by siRNA. We further identify Kif9 as a new regulator of spindle dynamics. Kif9 depletion increases the steady-state levels of spindle α-tubulin by increasing the rate of microtubule polymerization. Overall, this study demonstrates a novel mechanism by which Gem contributes to the mitotic progression by maintaining correct spindle length through the kinesin Kif9.

  9. Gemcitabine-loaded albumin nanospheres (GEM-ANPs) inhibit PANC-1 cells in vitro and in vivo

    Science.gov (United States)

    Li, Ji; Di, Yang; Jin, Chen; Fu, Deliang; Yang, Feng; Jiang, Yongjian; Yao, Lie; Hao, Sijie; Wang, Xiaoyi; Subedi, Sabin; Ni, Quanxing

    2013-04-01

    With the development of nanotechnology, special attention has been given to the nanomaterial application in tumor treatment. Here, a modified desolvation-cross-linking method was successfully applied to fabricate gemcitabine-loaded albumin nanospheres (GEM-ANPs), with 110 and 406 nm of mean diameter, respectively. The aim of this study was to assess the drug distribution, side effects, and antitumor activity of GEM-ANPs in vivo. The metabolic viability and flow cytometry analysis revealed that both GEM-ANPs, especially 406-nm GEM-ANPs, could effectively inhibit the metabolism and proliferation and promote the apoptosis of human pancreatic carcinoma (PANC-1) in vitro. Intravenous injection of 406-nm GEM-ANPs exhibited a significant increase of gemcitabine in the pancreas, liver, and spleen of Sprague-Dawley rats ( p tumor mice, intravenous injection of 406-nm GEM-ANPs also could effectively reduce the tumor volume by comparison with free gemcitabine. With these findings, albumin nanosphere-loading approach might be efficacious to improve the antitumor activity of gemcitabine, and the efficacy is associated with the size of GEM-ANPs.

  10. Therapiemonitoring mit bildgebenden Verfahren im modernen Management von Hirntumoren

    Directory of Open Access Journals (Sweden)

    Gerigk L

    2010-01-01

    Full Text Available Bildgebende Verfahren sind eine wichtige Grundlage der Therapieplanung und -kontrolle bei Hirntumoren. Bislang diente hierzu in erster Linie die Größenbeurteilung auf herkömmlichen morphologischen MRT-Aufnahmen. Sowohl zur besseren Therapieplanung und -kontrolle im Rahmen etablierter Therapieschemata als auch zur Evaluation neuer Therapieverfahren ist die Erfassung physiologischer Parameter wie der Perfusion, Diffusion oder Permeabilität mithilfe von MRT und PET eine vielversprechende Entwicklung. Mit der PET und entsprechenden Tracern können zusätzlich auch Targets zur Tumorklassifikation oder gezielten Therapie nachgewiesen werden. Mit der Spektroskopie können für Tumorgewebe typische Metabolite nachgewiesen werden. Bei einigen Tumorentitäten wie den niedergradigen Gliomen zeigten Studien, dass die Perfusionsbildgebung hilfreich zur Planung des weiteren therapeutischen Vorgehens sein kann. Ziel ist, durch eine Kombination geeigneter Verfahren zu einer frühen und treffsicheren Diagnostik beizutragen.

  11. Endokrinologische Behandlung der Geschlechtsdysphorie bei Menschen mit Geschlechtsinkongruenz

    Directory of Open Access Journals (Sweden)

    Flütsch N

    2015-01-01

    Full Text Available Es gibt Menschen, die die innere Gewissheit besitzen, dass ihre Geschlechtsidentität nicht zu ihrem biologischen Ursprungsgeschlecht passt. Durch die Entwicklungen in der Medizin in den letzten hundert Jahren ist es möglich geworden, die körperlichen Geschlechtsmerkmale an das innerlich erlebte Geschlecht anzupassen. Die Zahl der Hilfesuchenden in den ärztlichen Ambulanzen und Privatpraxen hat in den vergangenen Jahren deutlich zugenommen. Das Vorgehen bei der Diagnostik und Therapieeinleitung erlebt zurzeit eine deutliche Veränderung hin zu mehr Patientenzentriertheit und Individualisierung des Transitionsprozesses. Dabei bildet die geschlechtsangleichende Hormontherapie ein wesentliches Standbein in der körperlichen Angleichung an das Gegengeschlecht. Unter Beachtung von bestimmten Sicherheitsaspekten ist eine Hormontherapie mit Sexualhormonen sicher und einfach durchzuführen. Regelmäßige Verlaufskontrollen sowie der offene und affirmative Umgang mit den Betroffenen tragen zudem wesentlich zur Sicherheit in der Behandlung bei.

  12. Supermarket refrigerators with natural refrigerants; Supermarktkaelteanlagen mit natuerlichen Kaeltemitteln. Erfahrungsbericht

    Energy Technology Data Exchange (ETDEWEB)

    Haaf, S.; Heinbokel, B. [Linde AG, Koeln (Germany). Gechaeftsbereich Linde Kaeltetechnik

    2002-09-01

    In view of the high contribution to global warming of H-CFC refrigerants, substitution has been a key concern for several years now. Leakage protection measures were enhanced, and Linde also installed many supermarket refrigerators with natural refrigerants, i.e. ammonia, propene and carbon dioxide. The environmental and economic aspects are assessed on the basis of the experience gained, and the systems are compared with H-CFC refrigeration systems. [German] Wegen des betraechtlichen Treibhauspotentials von HFKW-Kaeltemitteln werden seit Jahren Anstrengungen unternommen, um den von diesen Stoffen ausgehenden Treibhauseffekt zu reduzieren. Neben Massnahmen zur Verminderung von Leckagen sowie zur Verringerung von Kaeltemittel-Fuellmengen wurden im Laufe der letzten 10 Jahre von Linde auch zahlreiche Kaelteanlagen mit den natuerlichen Kaeltemitteln Ammoniak, Propen und Kohlendioxid in Supermaerkten installiert. Auf Basis der gesammelten Erfahrungen wird eine Einschaetzung der umweltspezifischen und wirtschaftlichen Aspekte im Vergleich zu Anlagen mit HFKW-Kaeltemitteln vorgenommen. (orig.)

  13. MIT Lincoln Laboratory: Technology in Support of National Security

    Science.gov (United States)

    2011-01-01

    Ralston Stephan Rejto Kenneth Roth Mordechai Rothschild Kenneth Senne Anthony Sharon David Shaver Israel Soibelman William Song David Spears Scott...Atomic Energy Authority on airborne samples collected north of Scotland , and by the Naval Research Laboratory on rainwater collected in Kodiak...Interest, Lexington, Mass.: MIT Lincoln Laboratory, 1995; new material was added by John Tabaczynski, Stephen Weiner, and Kenneth Roth . 2 L.J

  14. Third Culture Kids? Auslandsentsendung mit Kindern und Jugendlichen

    OpenAIRE

    2006-01-01

    Die Arbeit untersucht die langfristigen Auswirkungen von Auslandsaufenthalten im Kindesalter. Das Interesse richtet sich auf die Frage, welche Rolle der Auslandsaufenthalt für die Identität im Erwachsenenalter spielt. Zu diesem Zweck wurden qualitative Interviews mit Erwachsenen geführt, die in ihren Entwicklungsjahren durch den Umzug von ihrem Ursprungsland in ein fremdes Land – und wieder zurück – Transitionserfahrungen gemacht haben.

  15. Unverarbeitete Trauer in Familien mit einem psychosomatisch kranken Kind

    OpenAIRE

    Perinelli, Karin; Günther, Charlotte

    1983-01-01

    In einer Untersuchungsstudie über die psychosoziale Abwehr in psychosomatischen Familien interessierte der Befund, daß Eltern von Kindern, die psychosomatisch erkrankt sind, weitaus häufiger als Eltern in einer Vergleichsgruppe frühe Personenverluste zu verkraften hatten, die sie heute empfindlich gegen Trennung machen. Es wird gezeigt, wie das Auftreten eines psychosomatischen Symptoms beim Kind mit unverarbeiteter Trauer in seiner Familie in Zusammenhang stehen konnte. Der von Minuchin für ...

  16. Phytoremediation organischer Schadstoffe mit Hilfe von Phragmites australis

    OpenAIRE

    Neustifter, Juliane Erika

    2007-01-01

    Praxisorientierte Projekte an einer Kläranlage lieferten umfassende Einblicke in einen mit Phragmites australis, dem Schilfrohr, bepflanzten Bodenfilter und seine jahreszeitlichen Rhythmen. Es wurde festgestellt, dass der Filter eine ausgezeichnete Restreinigung und Pufferwirkung hat und sogar verschiedene endokrin wirksame Substanzen zurückhält. Es konnte gezeigt werden, dass Phragmites australis organische Schadstoffe aufnehmen kann und wichtige Entgiftungsenzyme für den Abbau dieser Xenobi...

  17. Hochauflösende Verarbeitung von Radardaten mit synthetischer Apertur

    OpenAIRE

    Mittermayer, Josef

    2006-01-01

    Diese Arbeit stellt das neuartige Frequenz-Skalierungs-Verfahren zur effizienten und genauen Verarbeitung von Spotlight-SAR-Daten ohne Interpolation vor. Es wird eine genaue Modellierung der Spotlight-Abbildungsgeometrie eingeführt. Eine neue analytische Formulierung für SAR-Rohdaten mit Dechirp on Receive-Operation wird abgeleitet. Aufbauend auf dieser Formulierung erfolgt die Entwicklung einer interpolationsfreien Korrektur der Zielentfernungsänderung, der sogenannten Frequenz-Skalierung. ...

  18. Topologie und Dynamische Netzwerke: Anwendungen Der Optimierung MIT Zukunft

    Science.gov (United States)

    Leugering, Günter; Martin, Alexander; Stingl, Michael

    Die optimale Auslegung von Infrastrukturen z. B. bei der Verkehrsplanung und bei der Planung von Versorgungssystemen, die optimale Strukturierung bzw. Formgebung von Materialien und Werkstücken z. B. im Leichtbau sind aktuelle Themen angewandter Forschung. In beiden Bereichen wurde bis in die jüngste Zeit vornehmlich eine simulationsbasierte Optimierung auf der Grundlage einer Parameterjustierung vorgenommen, die oft wenig systematisch und zeit- und kostenintensiv ist. Stattdessen erweisen sich modellbasierte mathematische Optimierungsalgorithmen zusammen mit moderner numerischer Simulations-und Visualisierungstechnologie zunehmend als Katalysator neuer Technologien. Eine so verstandene Mathematische Optimierung kann bereits auf beeindruckende Erfolgsgeschichten verweisen und so den Anspruch als eine Zukunftsdisziplin behaupten. Diesem Anspruch trägt die Einrichtung des DFG-Schwerpunktprogramms 1253, Optimierung mit partiellen Differentialgleichungen’ im Jahre 2006 Rechnung, in dem über 25 Projekte im Bundesgebiet sowohl auf die theoretische Fundierung, als auch und insbesondere auf die Verzahnung zwischen Methodenentwicklung und numerischer Realisierung fokussieren. Forschung im Bereich der mathematischen Optimierung und Steuerung von Prozessen bzw. Eigenschaften, die mit Hilfe partieller Differentialgleichungen, so genannten, verteilten Systemen’, beschrieben werden, erfolgt im Kontext konkreter und exemplarischer Anwendungssituationen, die neue mathematische Herausforderungen markieren: Sicherheitsvorgaben etwa bei der Belastung von Gas- und Frischwasserleitungen oder solche für die Belastbarkeit von Verkehrsflugzeugen führen auf Druckbeschränkungen bzw.

  19. PLC-controlled cryostats for the BlackGEM and MeerLICHT detectors

    Science.gov (United States)

    Raskin, Gert; Morren, Johan; Pessemier, Wim; Bloemen, Steven; Klein-Wolt, Marc; Roelfsema, Ronald; Groot, Paul; Aerts, Conny

    2016-08-01

    BlackGEM is an array of telescopes, currently under development at the Radboud University Nijmegen and at NOVA (Netherlands Research School for Astronomy). It targets the detection of the optical counterparts of gravitational waves. The first three BlackGEM telescopes are planned to be installed in 2018 at the La Silla observatory (Chile). A single prototype telescope, named MeerLICHT, will already be commissioned early 2017 in Sutherland (South Africa) to provide an optical complement for the MeerKAT radio array. The BlackGEM array consists of, initially, a set of three robotic 65-cm wide-field telescopes. Each telescope is equipped with a single STA1600 CCD detector with 10.5k x 10.5k 9-micron pixels that covers a 2.7 square degrees field of view. The cryostats for housing these detectors are developed and built at the KU Leuven University (Belgium). The operational model of BlackGEM requires long periods of reliable hands-off operation. Therefore, we designed the cryostats for long vacuum hold time and we make use of a closed-cycle cooling system, based on Polycold PCC Joule-Thomson coolers. A single programmable logic controller (PLC) controls the cryogenic systems of several BlackGEM telescopes simultaneously, resulting in a highly reliable, cost-efficient and maintenance-friendly system. PLC-based cryostat control offers some distinct advantages, especially for a robotic facility. Apart of temperature monitoring and control, the PLC also monitors the vacuum quality, the power supply and the status of the PCC coolers (compressor power consumption and temperature, pressure in the gas lines, etc.). Furthermore, it provides an alarming system and safe and reproducible procedures for automatic cool down and warm up. The communication between PLC and higher-level software takes place via the OPC-UA protocol, offering a simple to implement, yet very powerful interface. Finally, a touch-panel display on the PLC provides the operator with a user-friendly and robust

  20. The Growth Entrapment Model (GEM): New Insights from Molecular-Scale Simulations of Ti in Quartz

    Science.gov (United States)

    Watson, E. B.; Lanzillo, N. A.; Nayak, S. K.

    2011-12-01

    The growth entrapment model (GEM) put forth by Watson and Liang (Am. Min. 80, 1170-1187) and Watson (GCA 68, 1473-1488) offers a mechanism by which crystals can acquire non-equilibrium chemical or isotopic properties during growth from a uniform fluid medium. The GEM is based on the premise that the equilibrium properties of the near-surface region of a crystal differ from those of the bulk, much as the properties of nanocrystals differ from those of larger crystals of the same phase. In the GEM model, "capture" of the near-surface composition within a growing crystal-creating a non-equilibrium condition-depends upon the outcome of the competition between growth (which buries near-surface atoms) and diffusion (which attempts to restore equilibrium). In any application of the GEM model, the most uncertain input parameters are the near-surface diffusivity (D) and the equilibrium partition coefficient (F) between the near-surface region and the bulk lattice. Experimental measurement of these quantities is elusive because the relevant length scales are small (1-5 nm). However, molecular-scale simulations hold some promise for deducing relative values, as we illustrate here using Ti uptake in quartz as an example. We undertook ab initio molecular dynamics simulations based on a supercell approach to show that the binding energy of Ti^{4+} in quartz is a function of depth in the crystal within a few nanometers of the surface, confirming that F in the GEM model must differ from unity. We also show, using the meta-dynamics method to compute the unbiased diffusion path and corresponding energy barrier, that the activation energy for Ti^{4+} diffusion in the near-surface (2-3 nm deep) is substantially lower than that pertaining to the "deep" lattice diffusivity that is typically measured in diffusion experiments (which we also reproduced computationally). These findings substantiate the underlying phenomena upon which the GEM model is based, in addition to providing

  1. Progress on the realization of a new GEM based neutron diagnostic concept for high flux neutron beams

    Energy Technology Data Exchange (ETDEWEB)

    Croci, G.; Tardocchi, M. [Istituto di Fisica del Plasma, Associazione EURATOM-ENEA-CNR, Milano, Italy and INFN, Sez. di Milano-Bicocca, Milano (Italy); Rebai, M.; Cippo, E. Perelli; Gorini, G. [Dipartimento di Fisica, Università degli Studi di Milano-Bicocca, Milano, Italy and INFN, Sez. di Milano-Bicocca, Milano (Italy); Cazzaniga, C. [Dipartimento di Fisica, Università degli Studi di Milano-Bicocca, Milano (Italy); Palma, M. Dalla; Pasqualotto, R.; Tollin, M. [Consorzio RFX - Associazione Euratom-Enea sulla Fusione, Padova (Italy); Grosso, G.; Muraro, A. [Istituto di Fisica del Plasma, Associazione EURATOM-ENEA-CNR, Milano (Italy); Murtas, F.; Claps, G. [INFN, Laboratori Nazionali di Frascati, Frascati (Roma) (Italy); Cavenago, M. [INFN, Laboratori Nazionali di Legnaro, Legnaro (Padova) (Italy)

    2014-08-21

    Fusion reactors will need high flux neutron detectors to diagnose the deuterium-deuterium and deuterium-tritium. A candidate detection technique is the Gas Electron Multiplier (GEM). New GEM based detectors are being developed for application to a neutral deuterium beam test facility. The proposed detection system is called Close-contact Neutron Emission Surface Mapping (CNESM). The diagnostic aims at providing the map of the neutron emission due to interaction of the deuterium beam with the deuterons implanted in the beam dump surface. This is done by placing a detector in close contact, right behind the dump. CNESM uses nGEM detectors, i.e. GEM detectors equipped with a cathode that also serves as neutron-proton converter foil. After the realization and test of several small area prototypes, a full size prototype has been realized and tested with laboratory sources. Test on neutron beams are foreseen for the next months.

  2. Design and implementation of the infrastructure of HadGEM3: the next-generation Met Office climate modelling system

    Directory of Open Access Journals (Sweden)

    H. T. Hewitt

    2010-10-01

    Full Text Available This paper describes the development of a technically robust climate modelling system, HadGEM3, which couples the Met Office Unified Model atmosphere component, the NEMO ocean model and the Los Alamos sea ice model (CICE using the OASIS coupler. Details of the coupling and technical solutions are documented in the paper in addition to a description of the configurations of the individual submodels. The paper demonstrates that the implementation of the model has resulted in accurate conservation of heat and freshwater across the model components. The model performance in early versions of this climate model is briefly described to demonstrate that the results are scientifically credible. HadGEM3 is the basis for a number of modelling efforts outside of the Met Office, both within the UK and internationally. This documentation of the HadGEM3 system provides a detailed reference for developers of HadGEM3-based climate configurations.

  3. Progress on the realization of a new GEM based neutron diagnostic concept for high flux neutron beams

    Science.gov (United States)

    Croci, G.; Rebai, M.; Cazzaniga, C.; Palma, M. Dalla; Grosso, G.; Muraro, A.; Murtas, F.; Claps, G.; Pasqualotto, R.; Cippo, E. Perelli; Tardocchi, M.; Tollin, M.; Cavenago, M.; Gorini, G.

    2014-08-01

    Fusion reactors will need high flux neutron detectors to diagnose the deuterium-deuterium and deuterium-tritium. A candidate detection technique is the Gas Electron Multiplier (GEM). New GEM based detectors are being developed for application to a neutral deuterium beam test facility. The proposed detection system is called Close-contact Neutron Emission Surface Mapping (CNESM). The diagnostic aims at providing the map of the neutron emission due to interaction of the deuterium beam with the deuterons implanted in the beam dump surface. This is done by placing a detector in close contact, right behind the dump. CNESM uses nGEM detectors, i.e. GEM detectors equipped with a cathode that also serves as neutron-proton converter foil. After the realization and test of several small area prototypes, a full size prototype has been realized and tested with laboratory sources. Test on neutron beams are foreseen for the next months.

  4. Large Size GEM for Super Bigbite Spectrometer (SBS) Polarimeter for Hall A 12 GeV program at JLab

    CERN Document Server

    Gnanvo, Kondo; Nelyubin, Vladimir; Saenboonruang, Kiadtisak; Sacher, Seth; Wojtsekhowski, Bogdan

    2014-01-01

    We report on the R&D effort in the design and construction of a large size GEM chamber for the Proton Polarimeter of the Super Bigbite Spectrometer (SBS) in Hall A at Thomas Jefferson National Laboratory (JLab). The SBS Polarimeter trackers consist of two sets of four large chambers of size 200 cm x 60 cm. Each chamber is a vertical stack of four GEM modules with an active area of 60 cm x 50 cm. We have built and tested several GEM modules and we describe in this paper the design and construction of the final GEM as well as the preliminary results on performances from tests carried out in our detector lab and with test beams at Fermilab.

  5. Screening the Drug Sensitivity Genes Related to GEM and CDDP in the Lung Cancer Cell-lines

    Directory of Open Access Journals (Sweden)

    Chunyu YANG

    2009-10-01

    Full Text Available Background and objective Screening of small-cell lung cancer (SCLC and non-small cell lung cancer (NSCLC cell lines with gemcitabine hydrochloride (GEM and cisplatin (CDDP related to drug sensitivity gene might clarify the action mechanism of anti-cancer drugs and provide a new clue for overcoming drug resistance and the development of new anti-cancer drugs, and also provide theoretical basis for the clinical treatment of individual. Methods The drug sensitivity of CDDP and GEM in 4 SCLC cell lines and 6 NSCLC cell lines was determined using MTT colorimetric assay, while the cDNA macroarray was applied to detect the gene expression state related to drug sensitivity of 10 lung cancer cell line in 1 291, and the correlation between the two was analysized. Results There were 6 genes showing significant positive correlation (r≥0.632, P < 0.05 with GEM sensitivity; 45 genes positively related to CDDP; another 41 genes related to both GEM and CDDP (r≥± 0.4. Lung cancer with GEM and CDDP sensitivity of two types of drugs significantly related genes were Metallothinein (Signal transduction molecules, Cathepsin B (Organization protease B and TIMP1 (Growth factor; the GEM, CDDP sensitivity associated genes of lung cancer cell lines mainly distributed in Metallothinein, Cathepsin B, growth factor TIMP1 categories. Conclusion There existed drug-related sensitive genes of GEM, CDDP in SCLC and NSCLC cell lines; of these genes, Metallothinein, Cathepsin B and TIMP1 genes presented a significant positive correlation with GEM drug sensitivity, a significant negative correlation with CDDP drug sensitivity.

  6. The development and evaluation of mini-GEMs - short, focused, online e-learning videos in geriatric medicine.

    Science.gov (United States)

    Garside, Mark J; Fisher, James M; Blundell, Adrian G; Gordon, Adam L

    2016-04-06

    Mini Geriatric E-Learning Modules (Mini-GEMs) are short, focused, e-learning videos on geriatric medicine topics, hosted on YouTube, which are targeted at junior doctors working with older people. This study aimed to explore how these resources are accessed and used. The authors analyzed the viewing data from 22 videos published over the first 18 months of the Mini-GEM project. We conducted a focus group of U.K. junior doctors considering their experiences with Mini-GEMS. The Mini-GEMs were viewed 10,291 times over 18 months, equating to 38,435 minutes of total viewing time. The average viewing time for each video was 3.85 minutes. Learners valued the brevity and focused nature of the Mini-GEMs and reported that they watched them in a variety of settings to supplement clinical experiences and consolidate learning. Watching the videos led to an increase in self-reported confidence in managing older patients. Mini-GEMs can effectively disseminate clinical teaching material to a wide audience. The videos are valued by junior doctors due to their accessibility and ease of use.

  7. Construction of a Gas Electron Multiplier (GEM) Detector for Medical Imaging

    CERN Document Server

    Mondal, N N; Mazumdar, M R Dutta; Dubey, A K; Vioygi, Y P

    2013-01-01

    A prototype Gas Electron Multiplier (GEM) detector is under construction for medical imaging purposes. A single thick GEM of size 10x10 cm^2 is assembled inside a square shaped air-tight box which is made of Perspex glass. In order to ionize gas inside the drift field two types of voltage supplier circuits were fabricated, and array of 2x4 pads of each size 4x8 mm^2 were utilized for collecting avalanche charges. Preliminary testing results show that the circuit which produces high voltage and low current is better than that of low voltage and high current supplier circuit in terms of x-ray signal counting rates.

  8. GEM detector development for tokamak plasma radiation diagnostics: SXR poloidal tomography

    Science.gov (United States)

    Chernyshova, Maryna; Malinowski, Karol; Ziółkowski, Adam; Kowalska-Strzeciwilk, Ewa; Czarski, Tomasz; Poźniak, Krzysztof T.; Kasprowicz, Grzegorz; Zabołotny, Wojciech; Wojeński, Andrzej; Kolasiński, Piotr; Krawczyk, Rafał D.

    2015-09-01

    An increased attention to tungsten material is related to a fact that it became a main candidate for the plasma facing material in ITER and future fusion reactor. The proposed work refers to the studies of W influence on the plasma performances by developing new detectors based on Gas Electron Multiplier GEM) technology for tomographic studies of tungsten transport in ITER-oriented tokamaks, e.g. WEST project. It presents current stage of design and developing of cylindrically bent SXR GEM detector construction for horizontal port implementation. Concept to overcome an influence of constraints on vertical port has been also presented. It is expected that the detecting unit under development, when implemented, will add to the safe operation of tokamak bringing creation of sustainable nuclear fusion reactors a step closer.

  9. Dependence of Limited Growth Rate of High-Quality Gem Diamond on Growth Conditions

    Institute of Scientific and Technical Information of China (English)

    TIAN Yu; MA Hong-An; LI Shang-Sheng; XIAO Hong-Yu; ZHANG Ya-Fei; HUANG Guo-Feng; MA Li-Qiu; JIA Xiao-Peng

    2007-01-01

    The growth rate of diamond has been investigated for a long time and researchers have been attempting to enhance the growth rate of high-quality gem diamond infinitely. However, it has been found according to previous research results that the quality of diamond is debased with the increase of growth rate. Thus, under specific conditions, the growth rate of high-quality diamond cannot exceed a limited value that is called the limited growth rate of diamond. We synthesize a series of type Ib gem diamonds by temperature gradient method under high pressure and high temperature (HPHT) using the as-grown {100} face. The dependence of limited growth rate on growth conditions is studied. The results show that the limited growth rate increases when synthetic temperature decreases, also when growth time is prolonged.

  10. Application of GemDialogue and GemSet Colour System in Colour Description and Grading of Coloured Gemstones%GemDialogue和GemSet颜色系统在有色宝石颜色描述和分级中的应用

    Institute of Scientific and Technical Information of China (English)

    李立平; 陈华; 罗劬侃

    2005-01-01

    国际贸易中有色宝石的报价主要是按其总品质级别和克拉质量给出的.目前,国际上较为广泛采用的有色宝石的分级体系主要有美国宝石学院和美国宝石协会的两个体系.在有色宝石总品质中起决定作用的是颜色,对宝石颜色的描述和分级分别采用的是GIA的GemSet和Howard Rubin的GemDialogue颜色系统.主要介绍这两个系统的特点以及它们在有色宝石颜色描述和分级中的应用方法及应注意的问题.

  11. Data Management and Other Logistical Challenges for the GEMS: The Data Coordinating Center Perspective

    Science.gov (United States)

    Biswas, Kousick; Carty, Christina; Horney, Rebecca; Nasrin, Dilruba; Farag, Tamer H.; Kotloff, Karen L.; Levine, Myron M.

    2012-01-01

    The Cooperative Studies Program Coordinating Center provided the data management, administrative, and statistical support to the Global Enteric Multicenter Study (GEMS). The GEMS study, the largest epidemiological study in the diarrheal disease area among children <5 years of age, was carried out in 4 African countries and 3 Asian countries. Given the geographical and geopolitical differences among the countries, the administration of a centralized data management operation was a major challenge. The sheer volume of the data that were collected, regular transfer of the data to a centralized database, and the cleaning of the same also posed some challenges. This paper outlines the details of the support that the data coordinating center provided and the challenges faced during the course of the study. PMID:23169938

  12. Energy calibration of a GEM-TPC prototype with 83mKr

    Science.gov (United States)

    Schmitz, Roman

    2012-05-01

    A GEM-TPC has been built as a 10% scale prototype for the P¯ANDA experiment and as a full-scale prototype for the CBELSA/TAPS experiment (Fabbietti L, et al: Nucl Instrum Methods A 628:204, 2011). The intrinsic suppression of ion backflow into the drift volume makes it suitable for high rate/background environments. The GEM-TPC has been used as an inner tracking update for the FOPI experiment at GSI where cosmic and beam tests were performed. For calibration purposes a 83Rb source has been produced at the Bonn HISKP Cyclotron. Using the isomeric 83mKr evaporated by the source, a relative channel-wise gain calibration as well as gain estimation for different high voltage settings could be performed.

  13. TPC-like readout for thermal neutron detection using a GEM-detector

    CERN Document Server

    Flierl, Bernhard; Hertenberger, Ralf; Zeitelhack, Karl

    2015-01-01

    Spatial resolution of less than 200 um is challenging for thermal neutron detection. A novel readout scheme based on the time-projection-chamber (TPC) concept is used in a gaseous electron multiplier (GEM) detector. Thermal neutrons are captured in a single 2 um thick Boron-10 converter cathode and secondary Helium and Lithium ions are produced with a combined energy of 2.8 MeV. These ions have sufficient energy to form straight tracks of several mm length. With a time resolving 2-dimensional readout of 400 um pitch in both directions, based on APV25 chips, the ions are tracked and their respective origin in the cathode converter foil is reconstructed. Using an Ar-CO2 93:7% gas mixture, a resolution of 100 um (FWHM 235 um) has been observed with a triple GEM-detector setup at the Garching neutron source (FRMII) for neutrons of 4.7 Angstrom.

  14. Large gem diamonds from metallic liquid in Earth’s deep mantle

    Science.gov (United States)

    Smith, Evan M.; Shirey, Steven B.; Nestola, Fabrizio; Bullock, Emma S.; Wang, Jianhua; Richardson, Stephen H.; Wang, Wuyi

    2016-12-01

    The redox state of Earth’s convecting mantle, masked by the lithospheric plates and basaltic magmatism of plate tectonics, is a key unknown in the evolutionary history of our planet. Here we report that large, exceptional gem diamonds like the Cullinan, Constellation, and Koh-i-Noor carry direct evidence of crystallization from a redox-sensitive metallic liquid phase in the deep mantle. These sublithospheric diamonds contain inclusions of solidified iron-nickel-carbon-sulfur melt, accompanied by a thin fluid layer of methane ± hydrogen, and sometimes majoritic garnet or former calcium silicate perovskite. The metal-dominated mineral assemblages and reduced volatiles in large gem diamonds indicate formation under metal-saturated conditions. We verify previous predictions that Earth has highly reducing deep mantle regions capable of precipitating a metallic iron phase that contains dissolved carbon and hydrogen.

  15. First measurements with new high-resolution gadolinium-GEM neutron detectors

    Science.gov (United States)

    Pfeiffer, D.; Resnati, F.; Birch, J.; Etxegarai, M.; Hall-Wilton, R.; Höglund, C.; Hultman, L.; Llamas-Jansa, I.; Oliveri, E.; Oksanen, E.; Robinson, L.; Ropelewski, L.; Schmidt, S.; Streli, C.; Thuiner, P.

    2016-05-01

    European Spallation Source instruments like the macromolecular diffractometer (NMX) require an excellent neutron detection efficiency, high-rate capabilities, time resolution, and an unprecedented spatial resolution in the order of a few hundred micrometers over a wide angular range of the incoming neutrons. For these instruments solid converters in combination with Micro Pattern Gaseous Detectors (MPGDs) are a promising option. A GEM detector with gadolinium converter was tested on a cold neutron beam at the IFE research reactor in Norway. The μTPC analysis, proven to improve the spatial resolution in the case of 10B converters, is extended to gadolinium based detectors. For the first time, a Gd-GEM was successfully operated to detect neutrons with a measured efficiency of 11.8% at a wavelength of 2 Åand a position resolution better than 250 μm.

  16. First measurements with new high-resolution gadolinium-GEM neutron detectors

    CERN Document Server

    AUTHOR|(CDS)2070256; Birch, Jens; Etxegarai, Maddi; Hall-Wilton, Richard; Höglund, Carina; Hultman, Lars; Llamas-Jansa, Isabel; Oliveri, Eraldo; Oksanen, Esko; Robinson, Linda; Ropelewski, Leszek; Schmidt, Susann; Streli, Christina; Thuiner, Patrik

    2016-01-01

    European Spallation Source instruments like the macromolecular diffractometer, NMX, require an excellent neutron detection efficiency, high-rate capabilities, time resolution, and an unprecedented spatial resolution in the order of a few hundred micrometers over a wide angular range of the incoming neutrons. For these instruments solid converters in combination with Micro Pattern Gaseous Detectors (MPGDs) are a promising option. A GEM detector with gadolinium converter was tested on a cold neutron beam at the IFE research reactor in Norway. The {\\mu}TPC analysis, proven to improve the spatial resolution in the case of $^{10}$B converters, is extended to gadolinium based detectors. For the first time, a Gd-GEM was successfully operated to detect neutrons with an estimated efficiency of 10% at a wavelength of 2 {\\AA} and a position resolution better than 350 {\\mu}m.

  17. Optical readout of a triple-GEM detector by means of a CMOS sensor

    Energy Technology Data Exchange (ETDEWEB)

    Marafini, M. [INFN Sezione di Roma (Italy); Museo Storico della Fisica e Centro Studi e Ricerche “E. Fermi”, Roma (Italy); Patera, V. [INFN Sezione di Roma (Italy); Museo Storico della Fisica e Centro Studi e Ricerche “E. Fermi”, Roma (Italy); Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Pinci, D., E-mail: davide.pinci@roma1.infn.it [INFN Sezione di Roma (Italy); Sarti, A. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy); Dipartimento di Scienze di Base e Applicate per Ingegneria, Sapienza Università di Roma (Italy); Sciubba, A. [INFN Sezione di Roma (Italy); Museo Storico della Fisica e Centro Studi e Ricerche “E. Fermi”, Roma (Italy); Dipartimento di Scienze di Base e Applicate per Ingegneria, Sapienza Università di Roma (Italy); Spiriti, E. [Laboratori Nazionali di Frascati dell' INFN, Frascati (Italy)

    2016-07-11

    In last years, the development of optical sensors has produced objects able to provide very interesting performance. Large granularity is offered along with a very high sensitivity. CMOS sensors with millions of pixels able to detect as few as two or three photons per pixel are commercially available and can be used to read-out the optical signals provided by tracking particle detectors. In this work the results obtained by optically reading-out a triple-GEM detector by a commercial CMOS sensor will be presented. A standard detector was assembled with a transparent window below the third GEM allowing the light to get out. The detector is supplied with an Ar/CF{sub 4} based gas mixture producing 650 nm wavelength photons matching the maximum quantum efficiency of the sensor.

  18. Performance of the full size nGEM detector for the SPIDER experiment

    Science.gov (United States)

    Muraro, A.; Croci, G.; Albani, G.; Claps, G.; Cavenago, M.; Cazzaniga, C.; Dalla Palma, M.; Grosso, G.; Murtas, F.; Pasqualotto, R.; Perelli Cippo, E.; Rebai, M.; Tardocchi, M.; Tollin, M.; Gorini, G.

    2016-03-01

    The ITER neutral beam test facility under construction in Padova will host two experimental devices: SPIDER, a 100 kV negative H/D RF beam source, and MITICA, a full scale, 1 MeV deuterium beam injector. SPIDER will start operations in 2016 while MITICA is expected to start during 2019. Both devices feature a beam dump used to stop the produced deuteron beam. Detection of fusion neutrons produced between beam-deuterons and dump-implanted deuterons will be used as a means to resolve the horizontal beam intensity profile. The neutron detection system will be placed right behind the beam dump, as close to the neutron emitting surface as possible thus providing the map of the neutron emission on the beam dump surface. The system uses nGEM neutron detectors. These are Gas Electron Multiplier detectors equipped with a cathode that also serves as neutron-proton converter foil. The cathode is designed to ensure that most of the detected neutrons at a point of the nGEM surface are emitted from the corresponding beamlet footprint (with dimensions of about 40×22 mm2) on the dump front surface. The size of the nGEM detector for SPIDER is 352 mm×200 mm. Several smaller size prototypes have been successfully made in the last years and the experience gained on these detectors has led to the production of the full size detector for SPIDER during 2014. This nGEM has a read-out board made of 256 pads (arranged in a 16×16 matrix) each with a dimension of 22 mm×13 mm. This paper describes the production of this detector and its tests (in terms of beam profile reconstruction capability, uniformity over the active area, gamma rejection capability and time stability) performed on the ROTAX beam-line at the ISIS spallation source (Didcot-UK).

  19. Optically read out GEM-based TPC operation and preliminary scintillation studies

    CERN Document Server

    Galgoczi, Gabor

    2016-01-01

    The main goal of this project was to realise the reconstruction of tracks in an optically read out GEM (Gas Electron Multiplier) based Time Projection Chamber (TPC). Secondary goal was to initialise a series of systematic studies on the scintillation of particles in Ar/CF4 (80-20%) mixture. Track reconstruction is needed for primary scintillation studies as only tracks fully contained can be considered. A vetoing and trigerring logic was built for the TPC from NIM modules.

  20. Quantitative analysis of trace element concentrations in some gem-quality diamonds

    Science.gov (United States)

    McNeill, J.; Pearson, D. G.; Klein-Ben David, O.; Nowell, G. M.; Ottley, C. J.; Chinn, I.

    2009-09-01

    The geochemical signature of diamond-forming fluids can be used to unravel diamond-forming processes and is of potential use in the detection of so-called 'conflict' diamonds. While fluid-rich fibrous diamonds can be analyzed by a variety of techniques, very few data have been published for fluid-poor, gem-quality diamonds because of their very low impurity levels. Here we present a new ICPMS-based (ICPMS: inductively coupled plasma mass spectrometry) method for the analysis of trace element concentrations within fluid-poor, gem-quality diamonds. The method employs a closed-system laser ablation cell. Diamonds are ablated and the products trapped for later pre-concentration into solutions that are analyzed by sector-field ICPMS. We show that our limits of quantification for a wide range of elements are at the sub-pg to low pg level. The method is applied to a suite of 10 diamonds from the Cullinan Mine (previously known as Premier), South Africa, along with other diamonds from Siberia (Mir and Udachnaya) and Venezuela. The concentrations of a wide range of elements for all the samples (expressed by weight in the solid) are very low, with rare earth elements along with Y, Nb, Cs ranging from 0.01 to 2 ppb. Large ion lithophile elements (LILE) such as Rb and Ba vary from 1 to 30 ppb. Ti ranges from ppb levels up to 2 ppm. From the combined, currently small data set we observe two kinds of diamond-forming fluids within gem diamonds. One group has enrichments in LILE over Nb, whereas a second group has normalized LILE abundances more similar to those of Nb. These two groups bear some similarity to different groups of fluid-rich diamonds, providing some supporting evidence of a link between the parental fluids for both fluid-inclusion-rich and gem diamonds.

  1. GEM: a dynamic tracking model for mesoscale eddies in the ocean

    Science.gov (United States)

    Li, Qiu-Yang; Sun, Liang; Lin, Sheng-Fu

    2016-12-01

    The Genealogical Evolution Model (GEM) presented here is an efficient logical model used to track dynamic evolution of mesoscale eddies in the ocean. It can distinguish between different dynamic processes (e.g., merging and splitting) within a dynamic evolution pattern, which is difficult to accomplish using other tracking methods. To this end, the GEM first uses a two-dimensional (2-D) similarity vector (i.e., a pair of ratios of overlap area between two eddies to the area of each eddy) rather than a scalar to measure the similarity between eddies, which effectively solves the "missing eddy" problem (temporarily lost eddy in tracking). Second, for tracking when an eddy splits, the GEM uses both "parent" (the original eddy) and "child" (eddy split from parent) and the dynamic processes are described as the birth and death of different generations. Additionally, a new look-ahead approach with selection rules effectively simplifies computation and recording. All of the computational steps are linear and do not include iteration. Given the pixel number of the target region L, the maximum number of eddies M, the number N of look-ahead time steps, and the total number of time steps T, the total computer time is O(LM(N + 1)T). The tracking of each eddy is very smooth because we require that the snapshots of each eddy on adjacent days overlap one another. Although eddy splitting or merging is ubiquitous in the ocean, they have different geographic distributions in the North Pacific Ocean. Both the merging and splitting rates of the eddies are high, especially at the western boundary, in currents and in "eddy deserts". The GEM is useful not only for satellite-based observational data, but also for numerical simulation outputs. It is potentially useful for studying dynamic processes in other related fields, e.g., the dynamics of cyclones in meteorology.

  2. Searching evidences for spiral shocks in the quiescent Accretion disk of u gem

    Directory of Open Access Journals (Sweden)

    V. V. Neustroev

    2004-01-01

    Full Text Available Encontramos que el disco de acreci on en la etapa de quietud de U Gem, tiene una estructura complicada. A lo largo de la mancha brillante originada en la regi on de interacci on entre el chorro y las part culas del disco, hay tambi en indicaciones de choques espirales. El mapa Doppler y las variaciones en las separaciones del pico de las l neas de emisi on son indicativos de ello.

  3. Performance Test of a Triple GEM Detector at CERN n_TOF Facility

    CERN Document Server

    Claps, Gerardo; Murtas, Fabrizio; Pietropaolo, Antonino; Puddu, Silvia; Severino, Clizia Tecla; Silari, Marco

    2012-01-01

    The application of a triple GEM (Gas Electron Multiplier) for neutron detection was tested at the n_TOF facility at CERN. n_TOF allows the neutron energy distribution to be measured via a ~185 m time of flight path. A 20 GeV/c proton beam hits a lead target generating a neutron spectrum ranging from thermal energies to the GeV region. Due to their long flight path and short proton pulse, the neutron arrival times at the experimental area define their energy (1). A triple GEM detector with a 60 μm Polyethylene (PE) neutron converter and 40 μm of Aluminium, filled with an Ar-CO2 70-30% mixture, was installed a few meters downstream of the experimental area, just in front of the beam dump. The measurements were purely parasitic; they were conducted in parallel and without interfering with the official n_TOF scientific program. Using the n_TOF trigger it is possible to synchronize the GEM data acquisition in order to select a given neutron energy window and measure the detector efficiency as a function of neutr...

  4. ULTRAVIOLET SPECTROSCOPY OF PQ Gem AND V405 Aur FROM THE HST AND IUE SATELLITES

    Energy Technology Data Exchange (ETDEWEB)

    Sanad, M. R., E-mail: mrsanad1@yahoo.com [National Research Institute of Astronomy and Geophysics, Astronomy Department, Helwan—Cairo— Egypt (Egypt)

    2015-10-20

    Ultraviolet spectra of two intermediate polars (IPs), PQ Gem and V405 Aur, observed with Hubble Space Telescope (HST) Space Telescope Imaging Spectrograph and Faint Object Spectrograph and International Ultraviolet Explorer (IUE) satellites were analyzed during the period between 1994–2000. We estimated the reddening of the two systems from the 2200 Å feature. Six spectra of the two systems revealing modulations of line fluxes at different times are presented. PQ Gem and V405 Aur are featured by spectral lines in different ionization states. This paper focuses on the third ionized carbon emission line at 1550 Å and the first ionized helium emission line at 1640 Å produced in the optically thin outer region of the accretion curtain for the two systems by calculating spectral line fluxes. From HST and IUE data, we deduced ultraviolet luminosities and ultraviolet accretion rates for the two binary stars. The average temperature of the accretion streams for PQ Gem and V405 Aur are ∼4500 K and 4100 K, respectively. The results reveal that there are modulations in fluxes of spectral lines, ultraviolet luminosities, and ultraviolet accretion rates with time for both systems. These modulations are referred to the changes of both density and temperature as a result of the variations of mass transfer rate from the secondary star to the primary star. The current results are consistent with an accretion curtain model for IPs.

  5. A TPC-like readout method for high precision muon-tracking using GEM-detectors

    Energy Technology Data Exchange (ETDEWEB)

    Flierl, Bernhard; Biebel, Otmar; Bortfeldt, Jonathan; Hertenberger, Ralf; Klitzner, Felix; Loesel, Philipp; Mueller, Ralph [Ludwig-Maximilians-Universitaet Muenchen (Germany); Zibell, Andre [Julius-Maximilians-Universitaet Wuerzburg (Germany)

    2016-07-01

    Gaseous electron multiplier (GEM) detectors are well suited for tracking of charged particles. Three dimensional tracking in a single layer can be achieved by application of a time-projection-chamber like readout mode (μTPC), if the drift time of the electrons is measured and the position dependence of the arrival time is used to calculate the inclination angle of the track. To optimize the tracking capabilities for ion tracks drift gas mixtures with low drift velocity have been investigated by measuring tracks of cosmic muons in a compact setup of four GEM-detectors of 100 x 100 x 6 mm{sup 3} active volume each and an angular acceptance of -25 to 25 . The setup consists of three detectors with two-dimensional strip readout layers of 0.4 mm pitch and one detector with a single strip readout layer of 0.25 mm pitch. All strips are readout by APV25 frontend boards and the amplification stage in the detectors consists of three GEM-foils. Tracks are reconstructed by the μTPC-method in one of the detectors and are then compared to the prediction from the other three detectors defined by the center of charge in every detector. We report our study of Argon and Helium based noble gas mixtures with carbon-dioxide as quencher.

  6. The 2.3 GHz continuum survey of the GEM project

    CERN Document Server

    Tello, C; Torres, S; Bersanelli, M; Smoot, G F; Ferreira, I S; Cingoz, A; Lamb, J; Barbosa, D; Perez-Becker, D; Ricciardi, S; Currivan, J A; Platania, P; Maino, D

    2007-01-01

    In this paper we present the scope of the Galactic Emission Mapping (GEM) project and its results at 2.3 GHz. Its observational program was conceived and developed to reveal the large scale properties of Galactic synchrotron radiation in total intensity and polarisation through a self-consistent set of radio continuum surveys between 408 MHz and 10 GHz. GEM's unique observational strategy and experimental design aim at the production of foreground templates in order to address the mutual inconsistencies between existing surveys and the role of Galactic emission as the main source of astrophysical contamination in measurements of the Cosmic Microwave Background radiation. The GEM experiment uses a portable and double-shielded 5.5-m radiotelescope on a rotating platform to map 60 deg wide declination bands, from different observational sites, by circularly scanning the sky at 30 deg from the Zenith. The observations at 2.3 GHz were accomplished with a total power receiver, whose front-end HEMT was matched direc...

  7. Technological aspects of GEM detector design and assembling for soft x-ray application

    Science.gov (United States)

    Kowalska-Strzeciwilk, E.; Chernyshova, M.

    2016-09-01

    Various types of Micro Pattern Gas Detectors (MPGDs) found applications as tracking detectors in high energy particle physics experiments and as well as imaging detectors, especially for soft X-rays. These detectors offer several advantages like high count rate capability, good spatial and energy resolution, low cost and possibility of constructing large area detectors with very small dead area. Construction, like the triple Gas Electron Multiplier (GEM) detector has become a standard detector, which is widely used for different imaging applications. Some examples of such applications are: monitoring the impurity in plasma, imaging system for mapping of some parameters like pigment distributions using X-ray fluorescence technique[1], proton range radiography system for quality assurance in hadron therapy. Measuring of the Soft X-Ray (SXR) radiation of magnetic fusion plasma is a standard way of accessing valuable information, for example, about particle transport and MHD. The paper is focused on the design of GEM based soft Xray radiation detecting system which is under development. It is dedicated to study soft X-ray emission of plasma radiation with focus on tungsten emission lines energy region. The paper presents the designing, construction and assembling of a prototype of two triple-GEM detectors for soft-X ray application on the WEST device.

  8. Performance Verification of the Gravity and Extreme Magnetism Small Explorer GEMS X-Ray Polarimeter

    Science.gov (United States)

    Enoto, Teruaki; Black, J. Kevin; Kitaguchi, Takao; Hayato, Asami; Hill, Joanne E.; Jahoda, Keith; Tamagawa, Toru; Kanako, Kenta; Takeuchi, Yoko; Yoshikawa, Akifumi; Kenward, David

    2014-01-01

    olarimetry is a powerful tool for astrophysical observations that has yet to be exploited in the X-ray band. For satellite-borne and sounding rocket experiments, we have developed a photoelectric gas polarimeter to measure X-ray polarization in the 2-10 keV range utilizing a time projection chamber (TPC) and advanced micro-pattern gas electron multiplier (GEM) techniques. We carried out performance verification of a flight equivalent unit (1/4 model) which was planned to be launched on the NASA Gravity and Extreme Magnetism Small Explorer (GEMS) satellite. The test was performed at Brookhaven National Laboratory, National Synchrotron Light Source (NSLS) facility in April 2013. The polarimeter was irradiated with linearly-polarized monochromatic X-rays between 2.3 and 10.0 keV and scanned with a collimated beam at 5 different detector positions. After a systematic investigation of the detector response, a modulation factor greater than or equal to 35% above 4 keV was obtained with the expected polarization angle. At energies below 4 keV where the photoelectron track becomes short, diffusion in the region between the GEM and readout strips leaves an asymmetric photoelectron image. A correction method retrieves an expected modulation angle, and the expected modulation factor, approximately 20% at 2.7 keV. Folding the measured values of modulation through an instrument model gives sensitivity, parameterized by minimum detectable polarization (MDP), nearly identical to that assumed at the preliminary design review (PDR).

  9. Pathobiology of aging mice and GEM: background strains and experimental design.

    Science.gov (United States)

    Brayton, C F; Treuting, P M; Ward, J M

    2012-01-01

    The use of induced and spontaneous mutant mice and genetically engineered mice (and combinations thereof) to study cancers and other aging phenotypes to advance improved functional human life spans will involve studies of aging mice. Genetic background contributes to pathology phenotypes and to causes of death as well as to longevity. Increased recognition of expected phenotypes, experimental variables that influence phenotypes and research outcomes, and experimental design options and rationales can maximize the utility of genetically engineered mice (GEM) models to translational research on aging. This review aims to provide resources to enhance the design and practice of chronic and longevity studies involving GEM. C57BL6, 129, and FVB/N strains are emphasized because of their widespread use in the generation of knockout, transgenic, and conditional mutant GEM. Resources are included also for pathology of other inbred strain families, including A, AKR, BALB/c, C3H, C57L, C58, CBA, DBA, GR, NOD.scid, SAMP, and SJL/J, and non-inbred mice, including 4WC, AB6F1, Ames dwarf, B6, 129, B6C3F1, BALB/c,129, Het3, nude, SENCAR, and several Swiss stocks. Experimental strategies for long-term cross-sectional and longitudinal studies to assess causes of or contributors to death, disease burden, spectrum of pathology phenotypes, longevity, and functional healthy life spans (health spans) are compared and discussed.

  10. The HadGEM2-ES implementation of CMIP5 centennial simulations

    Directory of Open Access Journals (Sweden)

    C. D. Jones

    2011-03-01

    Full Text Available The scientific understanding of the Earth's climate system, including the central question of how the climate system is likely to respond to human-induced perturbations, is comprehensively captured in GCMs and Earth System Models(ESM. Diagnosing the simulated climate response, and comparing responses across different models, is crucially dependent on transparent assumptions of how the GCM/ESM has been driven – especially because the implementation can involve subjective decisions and may differ between modelling groups performing the same experiment. This paper outlines the climate forcings and setup of the Met Office Hadley Centre ESM, HadGEM2-ES for the CMIP5 set of centennial experiments. We document the prescribed greenhouse gas concentrations, aerosol precursors, stratospheric and tropospheric ozone assumptions, as well as implementation of land-use change and natural forcings for the HadGEM2-ES historical and future experiments following the Representative Concentration Pathways. In addition, we provide details of how HadGEM2-ES ensemble members were initialised from the control run and how the palaeoclimate and AMIP experiments, as well as the "emission-driven" RCP experiments were performed.

  11. Synthetic SXR diagnostic using GEM detectors on WEST: development in the prospect of tungsten monitoring

    CERN Document Server

    Jardin, A; O'Mullane, M; Chernyshova, M; Czarski, T; Malinowski, K; Kasprowicz, G; Wojenski, A; Pozniak, K; Malard, P; Bourdelle, C

    2016-01-01

    WEST (Tungsten Environment in Steady-State Tokamak) will be operating by the end of 2016 as a test bed for the ITER divertor components in long pulse operation. In this context, radiative cooling of highly ionized impurities like tungsten (W) sputtered from Plasma Facing Components (PFC) into the plasma core is a critical issue since even small impurity concentrations below 10-4 degrade significantly plasma performances and can lead to radiative collapse. In the plasma core, tungsten emission is dominant in the Soft X-ray (SXR) range 0.1 keV -- 15 keV with complex contributions from line transition, radiative recombination and Bremsstrahlung emission.This paper presents the recent development of a synthetic SXR diagnostic using GEM (Gas Electron Multiplier) detectors. This diagnostic will be used on WEST for W transport studies and will be equipped with two new GEM based poloidal cameras allowing 2D tomographic reconstructions with spectral resolution in energy bands. Thus once GEM response to plasma emissivi...

  12. A GEM-based dose imaging detector with optical readout for proton radiotherapy

    Energy Technology Data Exchange (ETDEWEB)

    Klyachko, A.V., E-mail: aklyachk@indiana.edu [Indiana University Cyclotron Operations, Indiana University Integrated Science and Accelerator Technology Hall, 2401 Milo. B. Sampson Ln., Bloomington, IN 47408 (United States); Moskvin, V. [Department of Radiation Oncology, School of Medicine, Indiana University, Indianapolis, IN 46202 (United States); Nichiporov, D.F.; Solberg, K.A. [Indiana University Cyclotron Operations, Indiana University Integrated Science and Accelerator Technology Hall, 2401 Milo. B. Sampson Ln., Bloomington, IN 47408 (United States)

    2012-12-01

    New techniques in proton radiation therapy and advances in beam delivery systems design such as beam scanning require accurate 2D dosimetry systems to verify the delivered dose distribution. Dose imaging detectors based on gas electron multipliers (GEMs) are capable of providing high sensitivity, improved dose measurement linearity, position resolution, fast response and accurate characterization of depth-dose distributions. In this work, we report on the development of a GEM-based dose imaging detector with optical readout using a CCD camera. A 10 Multiplication-Sign 10 cm{sup 2} detector has been tested in a 205 MeV proton beam in single- and double-GEM configurations. The detector demonstrates linearity in dose rate up to 100 Gy/min and position resolution ({sigma}) of 0.42 mm. Transverse non-uniformity of the detector response is {<=}10% before correction and the stability of the detector output throughout the day is within {+-}1%, with day-to-day reproducibility of about 10%. The depth-dose response of the detector is close to that of a wide-aperture air-filled ionization chamber and is in good agreement with Monte Carlo simulations.

  13. A Test of GEMS Astrometric Precision for Exoplanet Detection and Mass Measurement

    Science.gov (United States)

    Ammons, S. Mark; Marois, Christian; Macintosh, Bruce; Konopacky, Quinn; Neichel, Benoit; Galicher, Raphael; Bendek, Eduardo; Guyon, Olivier

    2014-08-01

    Precision astrometry is so far the only mainstream exoplanet detection technique that has yet to find a new planet. The unique capabilities of GeMS and GSAOI may finally be what we have been waiting for: the combination of a large aperture and wide-field AO correction for stable high-resolution wide-field diffraction-limited imaging. As part of this program, we have observed the astrometric calibrator star TYC 7122-00041-1 to demonstrate GeMS' long-term astrometric precision of < 0.4 mas in sparse fields (Ammons et al. 2013). Here, we propose two more epochs on the closest brown dwarf pair at 2 pc, WISE J1049-53 (Luhman 2013), newly discovered with Gemini in 2013 to be the third closest system known. GEMS will in one year obtain the best available projected relative orbits and a < 1% trigonometric distance, enabling precision masses and luminosity measurements for both L/T transition components of WISE 1049-53.

  14. Performances of a GEM-based Time Projection Chamber prototype for the AMADEUS experiment

    CERN Document Server

    Lener, M Poli; Corradi, G; Curceanu, C; D'Uffizi, A; Paglia, C; Vidal, A Romero; Sbardella, E; Scordo, A; Tagnani, D; Zmeskal, J

    2013-01-01

    A large number of high-energy and heavy-ion experiments successfully used Time Projection Chamber (TPC) as central tracker and particle identification detector. However, the performance requirements on TPC for new high-rate particle experiments greatly exceed the abilities of traditional TPC read out by multi-wire proportional chamber (MWPC). Gas Electron Multiplier (GEM) detector has great potential to improve TPC performances when used as amplification device. In this paper we present the R&D activity on a new GEM-based TPC detector built as a prototype for the inner part for AMADEUS, a new experimental proposal at the DAFNE collider at Laboratori Nazionali di Frascati (INFN), aiming to perform measurements of the low-energy negative kaons interactions in nuclei. In order to evaluate the GEM-TPC performances, a 10x10 cm2 prototype with a drift gap up to 15 cm has been realized. The detector was tested at the pM1 beam facility of the Paul Scherrer Institut (PSI) with low momentum pions and protons, witho...

  15. R&D on GEM Detectors for Forward Tracking at a Future Electron-Ion Collider

    CERN Document Server

    Zhang, Aiwu; Hohlmann, Marcus; Bai, Xinzhan; Gnanvo, Kondo; Liyanage, Nilanga K; Posik, Matt; Surrow, Bernd

    2015-01-01

    We report the status of R&D on large triple-GEM detectors for a forward tracker (FT) in an experiment at a future Electron Ion Collider (EIC) that will improve our understanding of QCD. We have designed a detector prototype specifically targeted for the EIC-FT, which has a trapezoidal shape with 30.1 degrees opening angle. We are investigating different detector assembly techniques and signal readout technologies, but have designed a common GEM foil to minimize NRE cost for foil production. The assembly techniques comprise either a purely mechanical method including foil stretching as pioneered by CMS but with certain modifications, or gluing foils to frames that are then assembled mechanically, or gluing foils to frames that are then glued together. The first two assembly techniques allow for re-opening chambers so that a GEM foil can be replaced if it is damaged. For readout technologies, we are pursuing a cost-effective one-dimensional readout with wide zigzag strips that maintains reasonable spatial r...

  16. Interaktion systemisch wirksamer Antimykotika mit der Aggregation humaner Thrombozyten in vitro

    OpenAIRE

    2011-01-01

    Patienten mit Krebserkrankungen und invasiven Pilzinfektionen haben ein hohes Risiko für Blutungen sowohl aufgrund verminderter Thrombozytenzahlen als auch der Neigung einiger Pilze zur Gefäßarrosion. In dieser Studie wurde Blut von zehn gesunden Freiwilligen in vitro mit den i.v.-Zubereitungen von 11 verschiedenen Antimykotika versetzt. Anschließend wurde die Thrombozytenaggregation mit der Methode der Impedanzaggregometrie untersucht. Amphotericin B Colloidal Dispersion, Amphotericin B ...

  17. Delir, postoperative kognitive Verschlechterung und Charles Bonnet-Syndrom bei Patienten mit Kataraktoperationen

    OpenAIRE

    Hämmerl, Thomas

    2005-01-01

    In der Klinik für Augenheilkunde an der TU München wurden 92 Patienten mit Kataraktoperationen zu Delir, postoperativer kognitiver Verschlechterung und Charles Bonnet-Syndrom untersucht. Ein Patient hatte ein Delir bei Aufnahme, keiner entwickelte ein postoperatives Delir. Eine Risikogruppe für einen komplizierten postoperativen Verlauf stellten die Patienten mit präoperativer kognitiver Beeinträchtigung (n=11) und die Patienten mit postoperativer kognitiver Verschlechterung (n=8) dar. Risiko...

  18. Antikoagulation bei Vorhofflimmern: Wie und mit welchem Medikament?

    Directory of Open Access Journals (Sweden)

    Gary T

    2015-01-01

    Full Text Available Direkte orale Antikoagulantien (DOAKs sind Alternativen zu Vitamin-K-Antagonisten (VKA bei Vorhofflimmerarrhythmie- (VHFA- Patienten und werden diese in dieser Indikation zu weiten Teilen ersetzen. Bei VHFA-Patienten mit Dialyse oder mechanischen Herzklappen sind VKA nach wie vor die einzige Option. Bei der Gabe von DOAKs sollte vor Therapieeinleitung auf das Vorhandensein von Begleiterkrankungen (z. B. Niereninsuffizienz, stattgehabte gastrointestinale Blutungen etc. sowie auf die Begleittherapie der Patienten (z. B. Amiodaron etc. geachtet werden, um die passende Substanz in der richtigen Dosierung zu wählen.

  19. Content Management von Leittexten mit XML Topic Maps

    Directory of Open Access Journals (Sweden)

    Johannes Busse

    2003-07-01

    Full Text Available Die Autoren definieren den Umgang mit internet- basierten Informations- und Kommunikationstechnologien als Schlüsselqualifikation für Studierende aller Fachrichtungen. Im vorliegenden Aufsatz beschreiben sie ein Projekt, das der Fachbereich Erziehungswissenschaften der Universität Heidelberg seit 2001 durchführt. Hier werden Studierende der Geistes- und Sozialwissenschaften zu "Lernberatern" ausgebildet, die als Multiplikatoren die notwendigen Kenntnisse erwerben. Die Teilnehmenden erarbeiten nach der "Leittextmethode" selbstgesteuert xml-basierte Contents. Dies setzt den Erwerb von informationstechnischen Kenntnissen voraus, der neben dem Aufbau eines (sowohl technischen als auch sozialen Netzwerks einen Schwerpunkt bildet.

  20. A Single Channel Measurement Svstem For Brain MIT

    Institute of Scientific and Technical Information of China (English)

    QINMing-xing; JIAOLi-cheng; WANGCong; LIShi-jun; DONGXiu-zhen; LUHua

    2004-01-01

    A single channel measurement system for brain MIT has been built. The system is composed of an exciting source unit, a detecting unit, a rotating and controlling unit, and imaging unit. The experiment results of single channel measurements show that the system output versus the conductivity of the objects was an approximate linear relationship when the diameter of an object was about 9cm and its conductivity was in 0.1 S/m, 0.7 S/m, 2S/m, 6S/m. The sensitivit yof the phase detector was 53 mV/degree from -10 to+10 degree.

  1. Patron-Driven Acquisition (PDA - ein Modell mit Zukunft?

    Directory of Open Access Journals (Sweden)

    Rainer Plappert

    2015-12-01

    Full Text Available Gestützt auf eine dreijährige Erfahrung mit der nutzergesteuerten Erwerbung an der UB Erlangen-Nürnberg beleuchtet der Beitrag die verschiedenen Rollen der an dieser Erwerbungsform beteiligten Akteure. Vor dem Hintergrund geänderter Geschäftsmodelle werden die zukünftigen Perspektiven der nutzergesteuerten Erwerbung in Deutschland kritisch hinterfragt. Based on a three years experience with Patron-Driven Acquisition at University library Erlangen-Nuremberg the article discusses the roles of the protagonists at this acquisition form. Regarding to modified business models the perspectives of Patron-Driven Acquision in Germany seems to be unconfident.

  2. Mit Mathematik zu Mehr Intelligenz in der Logistik

    Science.gov (United States)

    Möhring, Rolf H.; Schenk, Michael

    Die Lösung logistischer Probleme ist ein wichtiger Aspekt menschlichen Handelns seit Menschen gemeinsam zielgerichtet tätig wurden. Die Grundlagen dessen, was wir heute Logistik nennen, entstammen dem militärischen Bereich. So basierte z. B. das römische Imperium in starkem Maße auf militärisch-logistischen Glanzleistungen. Ob damals bereits mathematische Überlegungen eine Rolle spielten, wissen wir heute nicht. Jedoch versuchte z. B. Napoleon, der mit den bedeutendsten Mathematikern seiner Zeit befreundet war, den Transport seiner Truppen und die Verbreitung von Informationen zu optimieren und strategisch einzusetzen.1,2

  3. Innovative facades with photovoltaics; Innovative Fassaden mit Photovoltaik

    Energy Technology Data Exchange (ETDEWEB)

    Eicker, U. [Hochschule fuer Technik, Stuttgart (Germany)

    1999-10-01

    Having grown at a rate of 15% since the middle of the 1980s the photovoltaic market today commands an annual module production of more than 100 MW{sub p}. In Germany altogether 10,000 PV systems with a total power output of 10 MW{sub p} were newly installed in 1997 alone. In 1990 the market was boosted by the heavily subsidised 1000 roofs programme, under which in the end more than 2,000 systems were installed on the roofs of mostly one-family houses. With power ratings ranging from 1 to 5 kW these decentral plants require roof surface areas between 10 and 50 m-2. On average they generate 800 kWh of electricity per kW of installed power. According to a number of studies carried out in the early 1990s the total surface area on buildings available for photovoltaics amounts to an enormous potential of 1,000 km-2, which is equivalent to an electricity generating potential of 130 TWh (100 TWh on roofs and 30 TWh on facades), or 25% of Germany`s total electricity demand. The degree to which this potential will be realised in the long term will notably depend on whether convincing architectural solutions are found for integrating photovoltaic plants in roofs and facades. [Deutsch] Der Photovoltaikmarkt waechst weltweit seit Mitte der 80er Jahre um durchschnittlich 15% und liegt heute bei einer Jahresmodulproduktion ueber 100 MW{sub p}. In Deutschland wurden alleine 1997 etwa 10.000 PV-Systeme mit einer Gesamtleistung von 10 MW{sub p} installiert. Die Marktentwicklung wurde 1990 mit dem stark subventionierten 1000-Daecher Programm angestossen, in welchem schliesslich mehr als 2000 Systeme meist auf Daechern von Einfamilienhaeusern installiert wurden. Diese dezentralen Anlagen mit Leistungen zwischen 1 und 5 kW erfordern Dachflaechen zwischen 10 und 50 m{sup 2} und erzeugen im Schnitt 800 kWh Strom pro kW installierter Leistung. Das verfuegbare Flaechenpotential von Gebaeuden wurde Anfang der 90er Jahre in einer Reihe von Studien ermittelt und stellt mit etwa 1000 km{sup 2

  4. GEM-E3: A computable general equilibrium model applied for Switzerland

    Energy Technology Data Exchange (ETDEWEB)

    Bahn, O. [Paul Scherrer Inst., CH-5232 Villigen PSI (Switzerland); Frei, C. [Ecole Polytechnique Federale de Lausanne (EPFL) and Paul Scherrer Inst. (Switzerland)

    2000-01-01

    The objectives of the European Research Project GEM-E3-ELITE, funded by the European Commission and coordinated by the Centre for European Economic Research (Germany), were to further develop the general equilibrium model GEM-E3 (Capros et al., 1995, 1997) and to conduct policy analysis through case studies. GEM-E3 is an applied general equilibrium model that analyses the macro-economy and its interaction with the energy system and the environment through the balancing of energy supply and demand, atmospheric emissions and pollution control, together with the fulfillment of overall equilibrium conditions. PSI's research objectives within GEM-E3-ELITE were to implement and apply GEM-E3 for Switzerland. The first objective required in particular the development of a Swiss database for each of GEM-E3 modules (economic module and environmental module). For the second objective, strategies to reduce CO{sub 2} emissions were evaluated for Switzerland. In order to develop the economic, PSI collaborated with the Laboratory of Applied Economics (LEA) of the University of Geneva and the Laboratory of Energy Systems (LASEN) of the Federal Institute of Technology in Lausanne (EPFL). The Swiss Federal Statistical Office (SFSO) and the Institute for Business Cycle Research (KOF) of the Swiss Federal Institute of Technology (ETH Zurich) contributed also data. The Swiss environmental database consists mainly of an Energy Balance Table and of an Emission Coefficients Table. Both were designed using national and international official statistics. The Emission Coefficients Table is furthermore based on know-how of the PSI GaBE Project. Using GEM-E3 Switzerland, two strategies to reduce the Swiss CO{sub 2} emissions were evaluated: a carbon tax ('tax only' strategy), and the combination of a carbon tax with the buying of CO{sub 2} emission permits ('permits and tax' strategy). In the first strategy, Switzerland would impose the necessary carbon tax to achieve

  5. Quark Orbital Angular Momentum in the MIT Bag Model

    CERN Document Server

    Courtoy, A

    2016-01-01

    We present the results for the Generalized Transverse Momentum Distribution related to quark Orbital Angular Momentum, {\\it i.e.} $F_{14}$, in the MIT bag model. This model has been modified to include the Peierls--Yoccoz projection to restore translational invariance. Such a modification allows to fulfill more satisfactorily basic sum rules, that would otherwise be less elegantly carried out with the original version. Using the same model, we have calculated the twist-$3$ GPD that corresponds to Orbital Angular Momentum \\`a la Ji, through the Penttinen--Polyakov--Shuvaev--Strikman sum rule. Recently, a new relation between the two definitions of the quark Orbital Angular Momentum at the density level has been proposed, which we illustrate here within the model. The sum rule is fulfilled. Still within the framework of the MIT bag model, we analyze the Wandzura--Wilczek expression for the GPD of interest. The genuine quark-gluon contribution is evaluated directly thanks to the equation of motion of the bag, wh...

  6. MIT Lincoln Laboratory: Physics and Technology in the National Interest

    Science.gov (United States)

    Ralston, Richard

    2001-03-01

    This year, MIT is celebrating the 50th anniversary of the founding of Lincoln Laboratory, which was formed at the request of the DoD with the initial goal of developing a national air defense system. In its 50 years, the Laboratory staff have made significant contributions in diverse areas including radar imaging, satellite communications, digital signal processing, computer science, semiconductor materials and solid state physics. The Laboratory has been true to its mission statement, which places strong emphasis on the application of advanced electronics to R&D in the national interest. Much of the technology is transitioned to U.S. industry for both government and commercial use. Annually more than 500 publications and meeting speeches are given, and cooperative developments with industry have targeted technology transitions ranging from next-generation photolithographic tools to microchip lasers. The Laboratory staff have been granted over 400 patents, and license to this intellectual property is at the core of many of the over 70 spin-off companies. MIT employs 2,300 people at Lincoln, including 1,200 professionals with degrees in physics, math, computer science, materials science and the engineering disciplines. Two-fifths of the professional staff are at the doctoral level; over two-thirds hold advanced degrees. This presentation will describe recent examples of research challenges for physicists in a multidisciplinary project-oriented environment.

  7. Treatment planning with functional MRI; Strahlentherapieplanung mit der funktionellen MRT

    Energy Technology Data Exchange (ETDEWEB)

    Georg, P. [EBG MedAustron GmbH, Wiener Neustadt (Austria); Medizinische Universitaet Wien, Christian Doppler Labor fuer die Medizinische Strahlenforschung, Wien (Austria); Andrzejewski, P.; Georg, D. [Medizinische Universitaet Wien, Christian Doppler Labor fuer die Medizinische Strahlenforschung, Wien (Austria); Medizinische Universitaet Wien, Abteilung fuer medizinische Strahlenphysik, Univ. Klinik fuer Strahlentherapie, Wien (Austria); Pinker, K. [Medizinische Universitaet Wien, Christian Doppler Labor fuer die Medizinische Strahlenforschung, Wien (Austria); Medizinische Universitaet Wien, Abteilung fuer molekulare Bildgebung, Univ. Klinik fuer Radiologie und Nuklearmedizin, Wien (Austria)

    2015-12-15

    The aim of magnetic resonance imaging (MRI) guided radiotherapy is high precision in treatment delivery. With new developments it is possible to focus the high dose irradiation on the tumor while sparing the surrounding tissue. The achievements in precision of the treatment planning and delivery warrant equally precise tumor definition. In conventional radiation therapy it is necessary to carry out a planning computed tomography (CT). For many tumors there is also need for an additional morphological MRI because of more accurate tumor definition. In standard radiotherapy the tumor volume is irradiated with a homogeneous dose. The aim of functional multiparametric MRI is to visualize and quantify biological, physiological and pathological processes at the cellular and molecular levels. Based on this information it is possible to elucidate tumor biology and identify subvolumes of more aggressive behavior. They are often radiotherapy-resistant, leading to tumor recurrence thus requiring further dose escalation. The concept of inhomogeneous tumor irradiation according to its biological behavior is called dose painting. Dose painting is technically feasible. The expected clinical benefit is motivated by selective treatment adaptations based on biological tumor characteristics. Tumors show variable response to therapy underlining the need for individual treatment plans. This approach may lead not only to higher local control but also to better sparing of normal surrounding tissue. With the clinical implementation of dose painting, improvements in the therapeutic outcome can be expected. Due to the existing technical challenges, extensive collaboration between radiation oncologists, radiologists, medical physicists and radiation biologists is needed. (orig.) [German] Die Strahlentherapieplanung mit der funktionellen Magnetresonanztomographie (fMRT) zielt auf eine Hochpraezisionsradiotherapie ab. Mit den modernen Technologien ist es moeglich, die Strahlentherapie nahezu

  8. Messung der Vorwärts-Rückwärts-Ladungsassymetrie von b-Quarks bei Energien nahe der Z0-Resonanz. Untersuchung von Ereignissen mit initialem b-Quark unter Verwendung der Jetladungstechnik mit dem DELPHI Detektor

    CERN Document Server

    Schwering, Britta

    Messung der Vorwärts-Rückwärts-Ladungsassymetrie von b-Quarks bei Energien nahe der Z0-Resonanz. Untersuchung von Ereignissen mit initialem b-Quark unter Verwendung der Jetladungstechnik mit dem DELPHI Detektor

  9. Assessing International Product Design and Development Graduate Courses: The MIT-Portugal Program

    Science.gov (United States)

    Dori, Yehudit Judy; Silva, Arlindo

    2010-01-01

    The Product Design and Development (PDD) course is part of the graduate curriculum in the Engineering Design and Advanced Manufacturing (EDAM) study in the MIT-Portugal Program. The research participants included about 110 students from MIT, EDAM, and two universities in Portugal, Instituto Superior Técnico-Universidade Técnica de Lisboa (IST) and…

  10. Immunregulation bei aggressiver Parodontitis im Vergleich mit moderater chronischer Parodontitis und gesundem Parodontium

    OpenAIRE

    Schmidt, Jana

    2013-01-01

    Es ist davon auszugehen, dass Fehlfunktionen im Immunsystem mit der Ausprä-gung des Krankheitsbildes der aggressiven Parodontitis im Zusammenhang ste-hen. In dieser Arbeit sollen anhand klinischer, immunologischer und mikrobiologischer Untersuchungen ein immunologisches Risikoprofil bei Patienten mit aggressiver Parodontitis erschlossen, gegebenenfalls Unterschiede zur moderaten chronischen Parodontitis beleuchtet und explorativ Zusammenhänge zwischen immunologischen und mikrobiologischen Bef...

  11. Rapid-Prototyping hydraulisch härtender Calcium- und Magnesiumphosphatzemente mit lokaler Wirkstoffmodifikation

    OpenAIRE

    2012-01-01

    Ziel dieser Arbeit war die Herstellung individuell formbarer Strukturen mittels des 3D-Pulverdrucks auf Basis von bei Raumtemperatur hydraulisch abbindenden Knochenzementpulvern. Neben der Entwicklung neuartiger Zementformulierungen auf Basis von Magnesiumphosphaten war vor allem die gleichzeitige Ausstattung der Werkstoffe mit temperaturlabilen und bioaktiven Verbindungen ein wichtiger Entwicklungsschritt. Die Lokalisation der Wirkstoffe korreliert dabei mit entsprechenden Farbinformationen ...

  12. Scratch that: MIT's Mitchel Resnick Says Kids Should Do It for Themselves

    Science.gov (United States)

    Traylor, Scott

    2008-01-01

    Mitchel Resnick is a researcher, inventor, and professor at MIT's Media Laboratory in Cambridge, MA, and the founder of the Lifelong Kindergarten Group at MIT. He is the lead innovator behind many cutting-edge learning technologies and projects for children, including the Computer Clubhouse, PicoCrickets, and the wildly successful consumer…

  13. Design and implementation of the infrastructure of HadGEM3: the next-generation Met Office climate modelling system

    Directory of Open Access Journals (Sweden)

    H. T. Hewitt

    2011-04-01

    Full Text Available This paper describes the development of a technically robust climate modelling system, HadGEM3, which couples the Met Office Unified Model atmosphere component, the NEMO ocean model and the Los Alamos sea ice model (CICE using the OASIS coupler. Details of the coupling and technical solutions of the physical model (HadGEM3-AO are documented, in addition to a description of the configurations of the individual submodels. The paper demonstrates that the implementation of the model has resulted in accurate conservation of heat and freshwater across the model components. The model performance in early versions of this climate model is briefly described to demonstrate that the results are scientifically credible. HadGEM3-AO is the basis for a number of modelling efforts outside of the Met Office, both within the UK and internationally. This documentation of the HadGEM3-AO system provides a detailed reference for developers of HadGEM3-based climate configurations.

  14. Metal-mediated gem-Difluoroallylation of N-Acylhydrazones: Highly Efficient Synthesis of a,a-Difluorohomoallylic Amines

    Institute of Scientific and Technical Information of China (English)

    YUE Xuyi; QIU Xiaolong; QING Fengling

    2009-01-01

    Indium-mediated gem-difluoroallylation of aldehyde-derived N-acylhydrazones 1a-1q and 4a-4g with 3-bromo-3,3-difluoropropene 2 afforded a,a-difluorohomoallylic hydrazides 3a-3q and 5a-5g in high yields, re-spectively. Functional groups such as nitro, phenolic hydroxyl, benzyloxy and even C=C bonds of a,fl-unsaturated aldehydes were compatible under this mild and operationally simple gem-difluoroallylic reaction condition. By means of substitution of Zn powder for indium, gem-difluoroallylation of ketone-derived N-acylhydrazones 6a-6d also provided the corresponding a,a-difluorohomoallylic hydrazides 7a-7d in medium yields. The N-N bond cleavage of the hydrazide 3a proceeded smoothly to give the corresponding primary gem-difluorohomoallylic amine 8, which could be converted to gem-difluoro-δ-substituted α,β-unsaturated lactam 11 via acryloylation fol-lowed by ring closing metathesis (RCM) reaction.

  15. Study of long-term operation of triple-GEM detectors for the high rate environment in CMS

    CERN Document Server

    Merlin, Jeremie Alexandre

    2013-01-01

    The CMS GEM collaboration is working on the possible instrumentation of the high-eta region of the CMS Endcap with Gas Electron Multiplier (GEM) detectors, a technology capable to sustain the hostile environment that will be encountered at the high-luminosity LHC. To ensure the long-term operation of large triple-GEM detectors in the CMS experiment, we are performing a set of studies in order to measure and understand the aging effect of triple-GEM Muon chambers. The aging includes all the processes that lead to a significant degradation of the performances of the detector gain drop, non-uniformity, dark current, discharges and resolution loss. The project is focused on monitoring continuously the response of the detector when irradiated by a source of Cs 137 at CERN in the Gamma Irradiation Facility (GIF). Moreover, the new technology employed for stretching the GEM foils, so called NS2, introduces new, carefully chosen materials and components in the detectors. Outgassing tests are performed in order to va...

  16. Short-Term H$\\alpha$ Line Variations in Classical Be Stars: 59 Cyg and OT Gem

    Indian Academy of Sciences (India)

    K. T. Paul; S. B. Shruthi; Annapurni Subramaniam

    2017-03-01

    We present the optical spectroscopic study of two classical Be stars, 59 Cyg and OT Gem obtained over a period of few months in 2009. We detected a rare triple-peak H$\\alpha$ emission phase in 59 Cyg and a rapid decrease in the emission strength of H$\\alpha$ in OT Gem, which are used to understand their circumstellar disks. We find that 59 Cyg is likely to be rapid rotator, rotating at a fractional critical rotation of $\\sim$ 0.80. The radius of the H$\\alpha$ emission region for 59 Cyg is estimated to be \\( R_d/R_*\\) $\\sim$, assuming a Keplerian disk, suggesting that it has a large disk. We classify stars which have shown triple-peaks into two groups and find that the triple-peak emission in 59 Cyg is similar to $\\zeta$ Tau. OT Gem is found to have a fractional critical rotation of $\\sim$0.30, suggesting that it is either a slow rotator or viewed in low inclination. In OT Gem, we observed a large reduction in the radius of the H$\\alpha$ emission region from $\\sim$6.9 to $\\sim$1.7 in a period of three months, along with the reduction in the emission strength. Our observations suggest that the disk is lost from outside to inside during this disk loss phase in OT Gem.

  17. Ambient water quality in aquifers used for drinking-water supplies, Gem County, southwestern Idaho, 2015

    Science.gov (United States)

    Bartolino, James R.; Hopkins, Candice B.

    2016-12-20

    In recent years, the rapid population growth in Gem County, Idaho, has been similar to other counties in southwestern Idaho, increasing about 54 percent from 1990 to 2015. Because the entire population of the study area depends on groundwater for drinking water supply (either from self-supplied domestic, community, or municipal-supply wells), this population growth, along with changes in land use (including potential petroleum exploration and development), indicated to the public and local officials the need to assess the quality of groundwater used for human consumption. To this end, the U.S. Geological Survey, in cooperation with Gem County and the Idaho Department of Environmental Quality, assessed the quality of groundwater from freshwater aquifers used for domestic supply in Gem County. A total of 47 domestic or municipal wells, 1 spring, and 2 surface-water sites on the Payette River were sampled during September 8–November 19, 2015. The sampled water was analyzed for a variety of constituents, including major ions, trace elements, nutrients, bacteria, radionuclides, dissolved gasses, stable isotopes of water and methane, and either volatile organic compounds (VOCs) or pesticides.To better understand analytical results, a conceptual hydrogeologic framework was developed in which three hydrogeologic units were described: Quaternary-Tertiary deposits (QTd), Tertiary Idaho Group rocks (Tig), and Tertiary-Cretaceous igneous rocks (TKi). Water levels were measured in 30 wells during sampling, and a groundwater-level altitude map was constructed for the QTd and Tig units showing groundwater flow toward the Emmett Valley and Payette River.Analytical results indicate that groundwater in Gem County is generally of good quality. Samples collected from two wells contained water with fluoride concentrations greater than the U.S. Environmental Protection Agency (EPA) Maximum Contaminant Level (MCL) of 4 milligrams per liter (mg/L), six wells contained arsenic at

  18. Child Care is Everybody's Baby: A Comprehensive Report of Child Care Services, Past, Present, and Future at M.I.T. Final Child Care Proposals as Accepted by M.I.T.

    Science.gov (United States)

    Swartz, Marilyn S.

    The report on child care services at M.I.T. explores the following areas: (1) Planning Issues: Why Should M.I.T. Be Involved in Child Care?--educational concerns, services, benefits and costs, priorities, resource allocation; (2) Background for Planning; Current Institute Child Care Programs--a concise history, M.I.T. summer day camp, the…

  19. First Year K-12 Teachers as High Leverage Point to Implement GEMS Space Science Curriculum Sequence

    Science.gov (United States)

    Slater, Timothy F.; Mendez, B. J.; Schultz, G.; Wierman, T.

    2013-01-01

    The recurring challenge for curriculum developers is how to efficiently prepare K-12 classroom teachers to use new curricula. First-year teachers, numbering nearly 250,000 in the US each year, have the greatest potential to impact the largest number of students because they have potential to be in the classroom for thirty years. At the same time, these novice teachers are often the most open minded about adopting curricular innovation because they are not yet deeply entrenched in existing practices. To take advantage of this high leverage point, a collaborative of space scientists and science educators at the University of California, Berkeley’s Lawrence Hall of Science and Center for Science Education at the Space Sciences Laboratory with experts from the Astronomical Society of the Pacific, the University of Wyoming, and the CAPER Center for Astronomy & Physics Education experimented with a unique professional development model focused on helping master teachers work closely with pre-service teachers during their student teaching internship field experience. The Advancing Mentor and Novice Teachers in Space Science (AMANTISS) team first identified master teachers who supervise novice, student teachers and trained these master teachers to use the GEMS Space Science Curriculum Sequence. Then, these master teachers were mentored in coaching interning student teachers assigned to them in using GEMS materials. Evaluation showed that novice teachers mentored by the master teachers felt knowledgeable after teaching the GEMS units. However, they seemed relatively less confident about the solar system and objects beyond the solar system. Overall, mentees felt strongly at the end of the year that they have acquired good strategies for teaching the various topics, suggesting that the support they received while teaching and working with a mentor was of real benefit to them. Funding provided in part by NASA ROSES AMANTISS NNX09AD51G

  20. Development of the GEM tracker for the J-PARC E16 experiment

    Energy Technology Data Exchange (ETDEWEB)

    Komatsu, Yusuke, E-mail: komatsu@post.kek.jp [Department of Physics, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan); RIKEN Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Aoki, Kazuya [Institute of Particle and Nuclear Studies, KEK, 1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Aramaki, Yoki; En' yo, Hideto [RIKEN Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Kanno, Koki [Department of Physics, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan); RIKEN Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Kawama, Daisuke [RIKEN Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Masumoto, Shinichi [Department of Physics, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan); Nakai, Wataru [Department of Physics, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan); RIKEN Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Obara, Yuki [Department of Physics, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan); Ozawa, Kyoichiro; Sekimoto, Michiko [Institute of Particle and Nuclear Studies, KEK, 1-1 Oho, Tsukuba, Ibaraki 305-0801 (Japan); Shibukawa, Takuya [Department of Physics, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan); Takahashi, Tomonori [RIKEN Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Watanabe, Yosuke [Department of Physics, Graduate School of Science, University of Tokyo, 7-3-1 Hongo, Tokyo 113-0033 (Japan); Yokkaichi, Satoshi [RIKEN Nishina Center for Accelerator-Based Science, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan)

    2013-12-21

    The J-PARC E16 experiment has been proposed to measure the mass spectrum of ϕ mesons in nuclear matter to study the origin of QCD mass. The ϕ mesons are identified in the e{sup +}e{sup −} decay channel and the mass of these ϕ mesons is reconstructed using the momenta of the e{sup +} and e{sup −} pairs. A tracking detector for this experiment is composed of a position sensitive device that employs Gas Electron Multipliers (GEMs) with a two-dimensional readout board. The ionization electrons are amplified with a triple-GEM stack. The required position resolution is 100μm up to an incidence angle of 30°. Position resolutions and efficiencies of the tracking device are evaluated using a π{sup −} beam with a momentum of 1.0 GeV/c at the J-PARC K1.1BR beam line. A position resolution of better than 100μm is obtained by calculating the center of gravity of the charges on the readout strips when tracks arrive perpendicularly at the detector plane. Timing information of charge clusters is essential to improve the position resolutions for the inclined tracks. The arrival times of the charge clusters are derived from the wave forms collected by flash ADC modules. Using the arrival times of the clusters, the obtained position resolution is better than 100μm for the track inclinations of 15° and 30°. The detection efficiency is also investigated as a function of the GEM gains, and the operational voltage is optimized.

  1. Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

    Science.gov (United States)

    Wong, Alan S L; Choi, Gigi C G; Cui, Cheryl H; Pregernig, Gabriela; Milani, Pamela; Adam, Miriam; Perli, Samuel D; Kazer, Samuel W; Gaillard, Aleth; Hermann, Mario; Shalek, Alex K; Fraenkel, Ernest; Lu, Timothy K

    2016-03-01

    The orchestrated action of genes controls complex biological phenotypes, yet the systematic discovery of gene and drug combinations that modulate these phenotypes in human cells is labor intensive and challenging to scale. Here, we created a platform for the massively parallel screening of barcoded combinatorial gene perturbations in human cells and translated these hits into effective drug combinations. This technology leverages the simplicity of the CRISPR-Cas9 system for multiplexed targeting of specific genomic loci and the versatility of combinatorial genetics en masse (CombiGEM) to rapidly assemble barcoded combinatorial genetic libraries that can be tracked with high-throughput sequencing. We applied CombiGEM-CRISPR to create a library of 23,409 barcoded dual guide-RNA (gRNA) combinations and then perform a high-throughput pooled screen to identify gene pairs that inhibited ovarian cancer cell growth when they were targeted. We validated the growth-inhibiting effects of specific gene sets, including epigenetic regulators KDM4C/BRD4 and KDM6B/BRD4, via individual assays with CRISPR-Cas-based knockouts and RNA-interference-based knockdowns. We also tested small-molecule drug pairs directed against our pairwise hits and showed that they exerted synergistic antiproliferative effects against ovarian cancer cells. We envision that the CombiGEM-CRISPR platform will be applicable to a broad range of biological settings and will accelerate the systematic identification of genetic combinations and their translation into novel drug combinations that modulate complex human disease phenotypes.

  2. Application of GEM-based detectors in full-field XRF imaging

    Science.gov (United States)

    Dąbrowski, W.; Fiutowski, T.; Frączek, P.; Koperny, S.; Lankosz, M.; Mendys, A.; Mindur, B.; Świentek, K.; Wiącek, P.; Wróbel, P. M.

    2016-12-01

    X-ray fluorescence spectroscopy (XRF) is a commonly used technique for non-destructive elemental analysis of cultural heritage objects. It can be applied to investigations of provenance of historical objects as well as to studies of art techniques. While the XRF analysis can be easily performed locally using standard available equipment there is a growing interest in imaging of spatial distribution of specific elements. Spatial imaging of elemental distrbutions is usually realised by scanning an object with a narrow focused X-ray excitation beam and measuring characteristic fluorescence radiation using a high energy resolution detector, usually a silicon drift detector. Such a technique, called macro-XRF imaging, is suitable for investigation of flat surfaces but it is time consuming because the spatial resolution is basically determined by the spot size of the beam. Another approach is the full-field XRF, which is based on simultaneous irradiation and imaging of large area of an object. The image of the investigated area is projected by a pinhole camera on a position-sensitive and energy dispersive detector. The infinite depth of field of the pinhole camera allows one, in principle, investigation of non-flat surfaces. One of possible detectors to be employed in full-field XRF imaging is a GEM based detector with 2-dimensional readout. In the paper we report on development of an imaging system equipped with a standard 3-stage GEM detector of 10 × 10 cm2 equipped with readout electronics based on dedicated full-custom ASICs and DAQ system. With a demonstrator system we have obtained 2-D spatial resolution of the order of 100 μm and energy resolution at a level of 20% FWHM for 5.9 keV . Limitations of such a detector due to copper fluorescence radiation excited in the copper-clad drift electrode and GEM foils is discussed and performance of the detector using chromium-clad electrodes is reported.

  3. GEM-based TPC with CCD imaging for directional dark matter detection

    Science.gov (United States)

    Phan, N. S.; Lauer, R. J.; Lee, E. R.; Loomba, D.; Matthews, J. A. J.; Miller, E. H.

    2016-11-01

    The most mature directional dark matter experiments at present all utilize low-pressure gas Time Projection Chamber (TPC) technologies. We discuss some of the challenges for this technology, for which balancing the goal of achieving the best sensitivity with that of cost effective scale-up requires optimization over a large parameter space. Critical for this are the precision measurements of the fundamental properties of both electron and nuclear recoil tracks down to the lowest detectable energies. Such measurements are necessary to provide a benchmark for background discrimination and directional sensitivity that could be used for future optimization studies for directional dark matter experiments. In this paper we describe a small, high resolution, high signal-to-noise GEM-based TPC with a 2D CCD readout designed for this goal. The performance of the detector was characterized using alpha particles, X-rays, gamma-rays, and neutrons, enabling detailed measurements of electron and nuclear recoil tracks. Stable effective gas gains of greater than 1 × 105 were obtained in 100 Torr of pure CF4 by a cascade of three standard CERN GEMs each with a 140 μm pitch. The high signal-to-noise and sub-millimeter spatial resolution of the GEM amplification and CCD readout, together with low diffusion, allow for excellent background discrimination between electron and nuclear recoils down below ∼10 keVee (∼23 keVr fluorine recoil). Even lower thresholds, necessary for the detection of low mass WIMPs for example, might be achieved by lowering the pressure and utilizing full 3D track reconstruction. These and other paths for improvements are discussed, as are possible fundamental limitations imposed by the physics of energy loss.

  4. An X-ray imaging device based on a GEM detector with delay-line readout

    Science.gov (United States)

    Zhou, Yi; Li, Cheng; Sun, Yong-Jie; Shao, Ming

    2010-01-01

    An X-ray imaging device based on a triple-GEM (Gas Electron Multiplier) detector, a fast delay-line circuit with 700 MHz cut-off frequency and two dimensional readout strips with 150 μm width on the top and 250 μm width on the bottom, is designed and tested. The localization information is derived from the propagation time of the induced signals on the readout strips. This device has a good spatial resolution of 150 μm and works stably at an intensity of 105 Hz/mm2 with 8 keV X-rays.

  5. The BlackGEM array in search of black hole mergers: integrated performance modelling

    Science.gov (United States)

    Roelfsema, Ronald; Klein Wolt, Marc; Bloemen, Steven; Groot, Paul; Bettonvil, Felix; Balster, Harry; Dolron, Peter; van Elteren, Arjen; Engels, Arno; de Haan, Menno; ter Horst, Rik; Kragt, Jan; Navarro, Ramon; Nelemans, Gijs; Paalberends, Willem Jelle; Pal, Sari; Raskin, Gert; Rutten, Harrie; Scheers, Bart; Schuil, Menno; Sybilski, Piotr

    2016-07-01

    The Radboud University Nijmegen in collaboration with the NOVA Optical Infrared Instrumentation group at ASTRON is currently leading the development and realization of the BlackGEM observing facility. The BlackGEM science team aims to be the first to catch the optical counterpart of a gravitational wave event. The BlackGEM project will put an array of three medium-sized optical telescopes at the La Silla site of the European Southern Observatory in Chile. It is uniquely equipped to achieve a combination of wide-field and high sensitivity through its array-like approach. Each BlackGEM unit telescope is a modified Dall-Kirkham-type telescope consisting of a 65cm primary mirror, a 21cm spherical secondary mirror and a triplet corrector lens. The spatial resolution on the sky will be 0.56 asec/pixel and the total field-of-view per telescope is 2.7 square degrees. The main requirement is to achieve a 5-sigma sensitivity of 23rd magnitude within a 5-minute exposure under 15 m/s wind gust conditions. This demands a very stable optical system with tight control of all the error contributions. This has been realized with a spreadsheet based integrated instrument model. The model contains all relevant telescope instrument parameters and environmental conditions. The spreadsheet is partly used for performance calculations and partly used to combine and integrate the output from several other sources. The spreadsheet model calculates the overall performance based on an Exposure Time Calculator using the Noise Equivalent Area metric (NEA). The NEA is further budgeted over 7 main High Level Requirements. The spreadsheet model is coupled to 1) a ZEMAX telescope optical model 2) a telescope FEM analysis to predict the optomechanical response under various gravity, temperature and wind load conditions, 3) a Matlab Simulink thermal model to predict the transient temperature behaviour of the most important telescope elements and 4) a Matlab Simulink control model to predict the

  6. Preparation of SRN1-type coupling adducts from aliphatic gem-dinitro compounds in ionic liquids.

    Science.gov (United States)

    Kamimura, Akio; Toyoshima, Seiichi

    2012-04-25

    S(RN)1-type coupling adducts are readily prepared by the reaction between a-sulfonylesters or a-cyanosulfones and gem-dinitro compounds in ionic liquids. The reactions progress smoothly and recovered ionic liquids can be used for several iterations, as long as they are washed with water to remove alkali metallic salts. The reaction rate is slower than the corresponding S(RN)1 reaction in DMSO, but no acceleration on irradiation or no inhibition in the presence of m-DNB are observed.

  7. An Entrepreneurial Well-being Model based on GEM Data for Spain

    Directory of Open Access Journals (Sweden)

    José Manuel Sáiz-Álvarez

    2014-03-01

    Full Text Available The Economics of Happiness is one of the research areas of greatest growth in recent years. Throughout this work, a venture based model in which satisfaction of Spanish entrepreneurs with their professional life is performed. We analyze the responses of 9,989 entrepreneurs using data from the Global Entrepreneurship Monitor (GEM, and six hypothesis are discussed. The results show that, for the Spanish case, there is a strong consistency in the results the opportunity entrepreneurs present greater satisfaction than necessity entrepreneurs.

  8. Modeling of serial data acquisition structure for GEM detector system in Matlab

    Science.gov (United States)

    Kolasinski, Piotr; Pozniak, Krzysztof T.; Czarski, Tomasz; Chernyshova, Maryna; Kasprowicz, Grzegorz; Krawczyk, Rafal D.; Wojenski, Andrzej; Zabolotny, Wojciech; Byszuk, Adrian

    2016-09-01

    This article presents method of modeling in Matlab hardware architecture dedicated for FPGA created by languages like VHDL or Verilog. Purposes of creating such type of model with its advantages and disadvantages are described. Rules presented in this article were exploited to create model of Serial Data Acquisition algorithm used in X-ray GEM detector system. Result were compared to real working model implemented in VHDL. After testing of basic structure, other two structures were modeled to see influence parameters of the structure on its behavior.

  9. 独具一格的Dynavox GEM Opal音箱

    Institute of Scientific and Technical Information of China (English)

    云断峰

    2003-01-01

    @@ 说到音箱,相信绝大部分读者都会想到那个四四方方的矩形箱体.的确,市面绝大多数音箱就是给我们留下这样的印象,音箱还有不同于矩形的设计吗?当然有,在这里笔者就为读者介绍一款来自德国的两分频中型座地箱Dynavox GEM Opal.

  10. Operating experience with innovative environmental technologies; Betriebserfahrungen mit innovativen Umwelttechnologien

    Energy Technology Data Exchange (ETDEWEB)

    Spindler, H.; Bauermeister, U.; Kliche, H.; Seiffarth, K. (comps.)

    2000-03-01

    The MUT '99 (Merseburger Umwelt-Tag) discussed modern processes, technologies and plants for treatment and utilisation of waste. The conference was attended by industrial organisations and scientific institutions. [German] Der 9. Merseburger Umwelt-Tag MUT '99 steht unter dem Motto 'Betriebserfahrungen mit innovativen Umwelttechnologien - Moderne wirtschaftliche Verfahren, Technologien und Anlagen zur Behandlung/Verwertung nichtvermeidbaren Abfalls', wobei der Begriff 'Abfall' sich letztlich auf alle Umweltmedien bezieht. Entsprechend dem Motto dieser Tagung stellen Unternehmen, Betriebe und wissenschaftliche Einrichtungen ihre Erfahrungen auf dem Gebiet der Umwelttechnologien vor, um Entwicklungen auf diesem Gebiet einer breiten Diskussion zu eroeffnen. Dabei soll es insbesondere um die Behandlung nicht vermeidbarer Abfaelle und Abwaesser gehen. (orig.)

  11. Operation of gas electron multiplier (GEM) with propane gas at low pressure and comparison with tissue-equivalent gas mixtures

    Energy Technology Data Exchange (ETDEWEB)

    De Nardo, L., E-mail: laura.denardo@unipd.it [University of Padova, Physics and Astronomy Department and PD-INFN, via Marzolo 8, I-35131 Padova (Italy); Farahmand, M., E-mail: majid.farahmand@rivm.nl [Centre for Environmental Safety and Security, National Institute for Public Health and the Environment (RIVM), PO Box 1, NL-3720 BA Bilthoven (Netherlands)

    2016-05-21

    A Tissue-Equivalent Proportional Counter (TEPC), based on a single GEM foil of standard geometry, has been tested with pure propane gas at low pressure, in order to simulate a tissue site of about 1 µm equivalent size. In this work, the performance of GEM with propane gas at a pressure of 21 and 28 kPa will be presented. The effective gas gain was measured in various conditions using a {sup 244}Cm alpha source. The dependence of effective gain on the electric field strength along the GEM channel and in the drift and induction region was investigated. A maximum effective gain of about 5×10{sup 3} has been reached. Results obtained in pure propane gas are compared with gas gain measurements in gas mixtures commonly employed in microdosimetry, that is propane and methane based Tissue-Equivalent gas mixtures.

  12. Quality Control of the Large-area GEM detectors at Production Sites for the CMS Muon Endcap Upgrade

    Science.gov (United States)

    Rahmani, Mehdi; CMS Collaboration

    2017-01-01

    GEM (Gas Electron Multipliers) detectors will be installed in the high-eta region of the CMS muon system by the year 2019. With precise tracking and fast trigger information, these detectors will significantly improve the CMS muon triggering after the second long shutdown of the LHC. There are six sites, external to CERN, where at total of 160 1-meter long GEM detectors will be produced. We present the detector construction and discuss the critical quality control (QC) procedures implemented for chamber commissioning. Some of the most important QCs discussed are: current leakage tests, gas leak tests, gain measurements, high voltage test and response uniformity test. We discuss the criteria that are used to accept or reject a GEM detector based on the QC results. The production and QC status will be presented as well.

  13. Pathophysiologie des Kollagenstoffwechsels bei Patienten mit Induratio penis plastica (IPP

    Directory of Open Access Journals (Sweden)

    Lahme S

    2000-01-01

    Full Text Available Die Pathogenese der IPP ist bis heute nicht geklärt. Histopathologische Untersuchungen zeigen, daß der Kollagenstoffwechsel eine Rolle spielt. Dies veranlaßte uns zur genauen Analyse der Kollagenstoffwechselparameter bei IPP. Bei 11 Patienten mit IPP und 11 Kontrollpersonen wurden Kollagenstoffwechselparameter (Prokollagen III [PIIIP], PMN-Elastase [PMN-E], Fibronektin [FN], Fibronektinrezeptor [FN-R] und alpha1-Proteinase-Inhibitor [alpha1-PI] im cavernösen und peripheren Blut bestimmt. PMN-E, PIIIP, FN und FN-R waren in den beiden Untersuchungsgruppen nicht unterschiedlich. Die peripher venösen unterschieden sich nicht von den cavernösen Blutproben. Sowohl im peripher venös (158,55 mg/dl als auch im cavernös entnommenen Blut (168,29 mg/dl war die Konzentration des a1-PI signifikant niedriger als in der Kontrollgruppe (214,82 mg/dl. An einem zweiten Kollektiv von 23 Patienten wurden Analysen des Phänotyps für alpha1-PI im Hinblick auf das Vorliegen von genetisch determinierten Mangelallelen vorgenommen. Hier zeigte sich kein signifikanter Unterschied zu einem Kontrollkollektiv von 19 gesunden Probanden. Die alpha1-PI Erniedrigung der IPP-Patienten ist signifikant und liegt unterhalb des Normalwertbereichs für die gesunde Population. Ein Mangel an alpha1-PI kann zur Aktivitätserhöhung der Proteasen und zum Umbau des Kollagengewebes führen. Möglicherweise kommt es zusammen mit einem lokal wirksamen Einflußfaktor schließlich zur dystrophen Kalzifikation. Die humangenetischen Untersuchungen sprechen nicht für eine genetische Determinierung des alpha1-PI-Mangels, sondern legen eine erworbene hepatische Störung nahe.

  14. Mountain Gem Russet: A medium to late season potato variety with high early and full season yield potential and excellent fresh market characteristics

    Science.gov (United States)

    Mountain Gem Russet is a medium to late maturing variety with both high early and full season yields of oblong-long, medium-russeted tubers having higher protein content than those of standard potato varieties. Mountain Gem Russet has greater resistance to tuber late blight, tuber malformations and ...

  15. Patient mit Ostiumstenose-Hauptstamm und Bifurkationsstenose - R. interventricularis anterior / R. diagonalis

    Directory of Open Access Journals (Sweden)

    Kerschner K

    2005-01-01

    Full Text Available Die Indikation zu Eingriffen am Hauptstamm und komplexen Bifurkationsstenosen wird auch nach Einführung von Drug-eluting- Stents und neuen Techniken kontrovers diskutiert. Im folgenden wird über eine kombinierte Hauptstamm- und Bifurkationsintervention berichtet. Anamnese: Ein 66jähriger Patient mit seit zwei Monaten zunehmender Belastungsdyspnoe Stadium III (NYHA, verbunden mit thorakalem Oppressionsgefühl. Zustand nach zerebralem Insult mit geringen Residuen, permanentes Vorhofflimmern, unzureichend eingestellte Hypertonie, geringe Nierenfunktionseinschränkung, Hypercholesterinämie. Invasive Abklärung: Ventrikulographie: ausgedehnte Akinese diaphragmal, Hypokinesie des Restventrikels, Auswurffraktion 29 %. Angiographie: 50 % Ostiumstenose-Hauptstamm, Bifurkationsstenose R. interventricularis anterior (LAD mit dem großen 1. diagonalen Ast jeweils 90 % (echte Bifurkation Typ IV ICPS-Klassifikation, Y konfiguriert (Abb. 1. Geringe Sklerose der klein angelegten A. circumflexa, proximaler Verschluß rechte Koronararterie mit Kollateralen von links zur diffus sklerotischen Peripherie. Nach entsprechender Aufklärung über die Therapiemöglichkeiten wurde eine Bypass-Operation vom Patienten nicht gewünscht und die Intervention durchgeführt. Intervention: Führungskatheter EBU 4 7F (Launcher, Medtronic. Sondierung beider Äste mit einem BMW-Führungsdraht (Balance Middleweight, Guidant Corp. und sequentielle Vordehnung R. diagonalis und LAD mit einem 2,5 / 20 mm-Ballon (Hypro Pegaso Sorin, Biomedica mit 16 atm. Plazierung eines 2,75 / 24 mm-Taxus-Express-2-Stent (Boston Scientific im R. diagonalis und eines 3,0 / 28 mm-Taxus-Express-2-Stent im LAD und Implantation in Crush-Technik (Abb. 2, jeweils 14 atm, mit dem Stent im R. diagonalis als gecrushtem Stent. Resondierung des R. diagonalis und Vordehnung des Abganges mit einem 1,5 und 2,5 mm-Ballon mit 20 atm und anschließende Kissing-Ballondilatation R. diagonalis 2,5 mm und LAD 3,0 mm

  16. Gillespie eco-evolutionary models (GEMs) reveal the role of heritable trait variation in eco-evolutionary dynamics.

    Science.gov (United States)

    DeLong, John P; Gibert, Jean P

    2016-02-01

    Heritable trait variation is a central and necessary ingredient of evolution. Trait variation also directly affects ecological processes, generating a clear link between evolutionary and ecological dynamics. Despite the changes in variation that occur through selection, drift, mutation, and recombination, current eco-evolutionary models usually fail to track how variation changes through time. Moreover, eco-evolutionary models assume fitness functions for each trait and each ecological context, which often do not have empirical validation. We introduce a new type of model, Gillespie eco-evolutionary models (GEMs), that resolves these concerns by tracking distributions of traits through time as eco-evolutionary dynamics progress. This is done by allowing change to be driven by the direct fitness consequences of model parameters within the context of the underlying ecological model, without having to assume a particular fitness function. GEMs work by adding a trait distribution component to the standard Gillespie algorithm - an approach that models stochastic systems in nature that are typically approximated through ordinary differential equations. We illustrate GEMs with the Rosenzweig-MacArthur consumer-resource model. We show not only how heritable trait variation fuels trait evolution and influences eco-evolutionary dynamics, but also how the erosion of variation through time may hinder eco-evolutionary dynamics in the long run. GEMs can be developed for any parameter in any ordinary differential equation model and, furthermore, can enable modeling of multiple interacting traits at the same time. We expect GEMs will open the door to a new direction in eco-evolutionary and evolutionary modeling by removing long-standing modeling barriers, simplifying the link between traits, fitness, and dynamics, and expanding eco-evolutionary treatment of a greater diversity of ecological interactions. These factors make GEMs much more than a modeling advance, but an important

  17. First demonstration of VUV-photon detection in liquid xenon with THGEM and GEM-based Liquid Hole Multipliers

    CERN Document Server

    Erdal, E; Rappaport, M; Shchemelinin, S; Vartsky, D; Breskin, A

    2016-01-01

    The bubble-assisted Liquid Hole-Multiplier (LHM) is a recently-introduced detection concept for noble-liquid time projection chambers. In this "local dual-phase" detection element, a gas bubble is supported underneath a perforated electrode (e.g., Thick Gas Electron Multiplier - THGEM, or Gas Electron Multiplier - GEM). Electrons drifting through the holes induce large electroluminescence signals as they pass into the bubble. In this work we report on recent results of THGEM and GEM electrodes coated with cesium iodide and immersed in liquid xenon, allowing - for the first time - the detection of primary VUV scintillation photons in addition to ionization electrons using LHMs.

  18. Design of a Constant Fraction Discriminator for the VFAT3 front-end ASIC of the CMS GEM detector

    CERN Document Server

    AUTHOR|(CDS)2069646; Abbas, M.; Abbrescia, M.; Abdelalim, A.A.; Abi Akl, M.; Aboamer, O.; Acosta, D.; Ahmad, A.; Ahmed, W.; Ahmed, W.; Aleksandrov, A.; Aly, R.; Altieri, P.; Asawatangtrakuldee, C.; Aspell, P.; Assran, Y.; Awan, I.; Bally, S.; Ban, Y.; Banerjee, S.; Barashko, V.; Barria, P.; Bencze, G.; Beni, N.; Benussi, L.; Bhopatkar, V.; Bianco, S.; Bos, J.; Bouhali, O.; Braghieri, A.; Braibant, S.; Buontempo, S.; Calabria, C.; Caponero, M.; Caputo, C.; Cassese, F.; Castaneda, A.; Cauwenbergh, S.; Cavallo, F.R.; Celik, A.; Choi, M.; Choi, S.; Christiansen, J.; Cimmino, A.; Colafranceschi, S.; Colaleo, A.; Conde Garcia, A.; Czellar, S.; Dabrowski, M.M.; De Lentdecker, G.; De Oliveira, R.; de Robertis, G.; Dildick, S.; Dorney, B.; Elmetenawee, W.; Endroczi, G.; Errico, F.; Fenyvesi, A.; Ferry, S.; Furic, I.; Giacomelli, P.; Gilmore, J.; Golovtsov, V.; Guiducci, L.; Guilloux, F.; Gutierrez, A.; Hadjiiska, R.M.; Hassan, A.; Hauser, J.; Hoepfner, K.; Hohlmann, M.; Hoorani, H.; Iaydjiev, P.; Jeng, Y.G.; Kamon, T.; Karchin, P.; Korytov, A.; Krutelyov, S.; Kumar, A.; Kim, H.; Lee, J.; Lenzi, T.; Litov, L.; Madorsky, A.; Maerschalk, T.; Maggi, M.; Magnani, A.; Mal, P.K.; Mandal, K.; Marchioro, A.; Marinov, A.; Masod, R.; Majumdar, N.; Merlin, J.A.; Mitselmakher, G.; Mohanty, A.K.; Mohamed, S.; Mohapatra, A.; Molnar, J.; Muhammad, S.; Mukhopadhyay, S.; Naimuddin, M.; Nuzzo, S.; Oliveri, E.; Pant, L.M.; Paolucci, P.; Park, I.; Passeggio,G.; Pavlov, B.; Philipps, B.; Piccolo, D.; Postema, H.; Puig Baranac, A.; Radi, A.; Radogna, R.; Raffone, G.; Ranieri, A.; Rashevski, G.; Riccardi, C.; Rodozov, M.; Rodrigues, A.; Ropelewski, L.; RoyChowdhury, S.; Ryu, G.; Ryu, M.S.; Safonov, A.; Salva, S.; Saviano, G.; Sharma, A.; Sharma, A.; Sharma, R.; Shah, A.H.; Shopova, M.; Sturdy, J.; Sultanov, G.; Swain, S.K.; Szillasi, Z.; Talvitie, J.; Tamma, C.; Tatarinov, A.; Tuuva, T.; Tytgat, M.; Vai, I.; Van Stenis, M.; Venditti, R.; Verhagen, E.; Verwilligen, P.; Vitulo, P.; Volkov, S.; Vorobyev, A.; Wang, D.; Wang, M.; Yang, U.; Yang, Y.; Yonamine, R.; Zaganidis, N.; Zenoni, F.; Zhang, A.

    2016-01-01

    In this work the design of a Constant Fraction Discriminator (CFD) to be used in the VFAT3 chip, currently under design for the read-out of the Triple-Gem detectors of the CMS experiment, is described. Simulations show that it is possible to extend the front-end shaping time in order to fully integrate the GEM detector signal charge whilst maintaining optimal timing resolution using the CFD technique. A prototype chip containing 8 CFDs was implemented in 130 nm CMOS technology to prove the effectiveness of the proposed architecture before its integration in the VFAT3 chip. The CFD design and test results will be shown.

  19. Inseltransplantation als Therapieoption bei Diabetes mellitus Typ 1: Für wen, mit welchem Ziel, mit welchem Erfolg?

    Directory of Open Access Journals (Sweden)

    Ludwig B

    2014-01-01

    Full Text Available Die Inseltransplantation hat sich als Behandlungsoption für Patienten mit Diabetes mellitus Typ 1 etabliert. In den meisten Zentren wird die Indikation gestellt, wenn konventionelle Therapiemethoden versagen und Patienten durch eine hochlabile Stoffwechsellage und rezidivierende Hypoglykämien gefährdet sind. Hintergrund für diese strikte Indikationsstellung ist die Notwendigkeit einer dauerhaften Immunsuppression und der kritische Mangel an verfügbaren Spenderorganen. Durch die Wiederherstellung einer endogenen Insulinsekretion kommt es zu einer zuverlässigen Stabilisierung des Blutzuckerprofils, Vermeidung von Hypoglykämien und Verhinderung bzw. Stabilisierung von Spätkomplikationen. Damit einher geht eine deutliche Verbesserung der Lebensqualität. Das Erreichen einer kompletten Insulinunabhängigkeit ist dabei nicht vorrangiges Therapieziel.

  20. Rekonstruktion mit Netz beim komplexen Prolaps der Frau: Was hilft es der Patientin wirklich?

    Directory of Open Access Journals (Sweden)

    Hierl J

    2010-01-01

    Full Text Available Einleitung: Der komplexe Genitaldeszensus der Frau geht oftmals mit einer deutlichen Einschränkung der Lebensqualität (LQ einher. Dennoch ist der Endpunkt der meisten klinischen Analysen rein anatomischer und funktioneller Natur. In der vorliegenden Untersuchung wurden die Einflüsse der operativen Rekonstruktion mit einem Netz prospektiv auf die LQ evaluiert. Patienten und Methoden: Bei insgesamt 111 Patientinnen mit Deszensus erfolgte zwischen 08/2005 und 12/2007 eine operative Versorgung mittels vaginaler Netzeinlage (anteriorer bzw. kompletter Mesh-Repair. Die LQ wurde prospektiv prä- und postoperativ anhand standardisierter LQ-Fragebögen erfasst. Ergebnisse: Präoperativ zeigte sich bei den Patientinnen eine signifikant reduzierte LQ gegenüber einem Normalkollektiv (p 0,01. Bei 7 % der Patientinnen mit anteriorem, und bei 11 % mit komplettem Mesh-Repair lag postoperativ kein adäquates klinisches Ergebnis vor. In diesem Kollektiv zeigte sich kein signifikanter Unterschied in den LQ-Tests prä- und postoperativ. Bei gutem postoperativem Ergebnis zeigte sich in der Gruppe mit anteriorer Netzeinlage lediglich bei 45 % (p = 0,021, bei kompletter Netzeinlage nur bei 31 % (p = 0,041 eine signifikant verbesserte LQ. Bei kleiner Fallzahl und kurzem Nachbeobachtungszeitraum kann eine gültige Aussage bezüglich der LQ nach Deszensuschirurgie mit Netzeinlage jedoch noch nicht getroffen werden.

  1. Virtual colonoscopy with multi-slice computed tomography; Virtuelle Koloskopie mit der Mehrschichtcomputertomographie. Vorlaeufige Ergebnisse

    Energy Technology Data Exchange (ETDEWEB)

    Rust, G.-F.; Eisele, O.; Reiser, M. [Institut fuer Klinische Radiologie, Klinikum Grosshadern, Muenchen Univ. (Germany); Hoffmann, J.N.; Kopp, R.; Fuerst, H. [Chirurgische Klinik und Poliklinik, Klinikum der Univ. Muenchen (Germany)

    2000-03-01

    Subject: Using multi-slice computed tomography (MSCT) large body areas can scanned with high spatial resolution. In this study, MSCT was employed for virtual colonoscopy in various pathologies of the colon. Results: Nine polyps and four of five colon carcinomas were detected using MSCT virtual colonoscopy. In three patients with ulcerative colitis virtual coloscopy revealed morphological alterations compatible with this disease. In two of four patients with multiple diverticula of the colon the true extent of the disorder could be assessed in virtual colonoscopy. (orig.) [German] Fragestellung: Die Mehrschichtcomputertomographie (MSCT) vermag, grosse Organbereiche mit hoher raeumlicher Aufloesung zu untersuchen. Daher koennen auch fuer die virtuelle Koloskopie eine bisher nicht erreichbare Ortsaufloesung und Detailtreue erwartet werden. Die ersten Ergebnisse mit der MSCT-Koloskopie bei unterschiedlichen pathologischen Veraenderungen des Kolons werden vorgestellt. Ergebnisse: 4 von 5 Kolonkarzinomen konnten mit der virtuellen Koloskopie dargestellt werden. Bei 3 Patienten wurden mit der virtuellen Koloskopie typische Veraenderungen der Colitis ulcerosa dargestellt, wovon ein Patient die konventionelle Koloskopie nicht tolerierte. Bei 9 Patienten mit Kolonpolypen stimmten die virtuelle und konventionelle Koloksopie vollstaendig ueberein. Bei 4 Patienten mit Divertikulose war mit der virtuellen Koloskopie nur in 2 Faellen der Befund vollstaendig zu sichern. (orig.)

  2. Reading a GEM with a VLSI pixel ASIC used as a direct charge collecting anode

    CERN Document Server

    Bellazzini, R; Baldini, L; Bitti, F; Brez, A; Latronico, L; Massai, M M; Minuti, M; Omodei, N; Razzano, M; Sgro, C; Spandre, G; Costa, E; Soffitta, P

    2004-01-01

    In MicroPattern Gas Detectors (MPGD) when the pixel size is below 100 micron and the number of pixels is large (above 1000) it is virtually impossible to use the conventional PCB read-out approach to bring the signal charge from the individual pixel to the external electronics chain. For this reason a custom CMOS array of 2101 active pixels with 80 micron pitch, directly used as the charge collecting anode of a GEM amplifying structure, has been developed and built. Each charge collecting pad, hexagonally shaped, realized using the top metal layer of a deep submicron VLSI technology is individually connected to a full electronics chain (pre-amplifier, shaping-amplifier, sample and hold, multiplexer) which is built immediately below it by using the remaining five active layers. The GEM and the drift electrode window are assembled directly over the chip so the ASIC itself becomes the pixelized anode of a MicroPattern Gas Detector. With this approach, for the first time, gas detectors have reached the level of i...

  3. Development of entrepreneurship in Brazil based on indicators of the global entrepreneurship monitor (GEM

    Directory of Open Access Journals (Sweden)

    Ana Carolina Cozza Josende da Silva

    2015-06-01

    Full Text Available Entrepreneurship is very important in a society due to its influence with the growth and development of a country. The importance of studying and knowing the entrepreneurial activity and the entrepreneur's profile contributes positively to identify estimates of this activity and to clarify the future of this process. In this sense, this article presents the evolution of entrepreneurship in Brazil over the past 13 years, using for the study secondary data obtained from the GEM and IBGE researches, in which the search was conducted in documentary basis from 2001 to 2013. The results present a descriptive analysis of the Global Entrepreneurship Monitor entrepreneurship indicators (GEM concerning to the new entrepreneur rate and the rate of nascent entrepreneurs, growth of the Brazilian GDP related to entrepreneurship, entrepreneurship rate according to the entrepreneur stages (initial and established, initial entrepreneurs according to their motivation (by chance and necessity, by gender entrepreneurs, age, level of education. It was also carried out statistical analysis where the trend of the variables over time was verified by simple linear regression at the significance level of 5%. The study concludes that Brazil tends to present significant growth towards entrepreneurship, an advancement of the female contribution to the economy, increase of entrepreneurs because of more opportunities and stability in the existing businesses.

  4. Smooth and Starburst Tidal Tails in the GEMS and GOODS Fields

    CERN Document Server

    Elmegreen, Debra Meloy; Ferguson, Thomas; Mullan, Brendan

    2007-01-01

    GEMS and GOODS fields were examined to z~1.4 for galaxy interactions and mergers. The basic morphologies are familiar: antennae with long tidal tails, tidal dwarfs, and merged cores; M51-type galaxies with disk spirals and tidal arm companions; early-type galaxies with diffuse plumes; equal-mass grazing-collisions; and thick J-shaped tails beaded with star formation and double cores. One type is not common locally and is apparently a loose assemblage of smaller galaxies. Photometric measurements were made of the tails and clumps, and physical sizes were determined assuming photometric redshifts. Antennae tails are a factor of ~3 smaller in GEMS and GOODS systems compared to local antennae; their disks are a factor of ~2 smaller than locally. Collisions among early type galaxies generally show no fine structure in their tails, indicating that stellar debris is usually not unstable. One exception has a 5x10**9 Msun smooth red clump that could be a pure stellar condensation. Most tidal dwarfs are blue and probab...

  5. Evidence for a companion to BM Gem, a silicate carbon star

    CERN Document Server

    Izumiura, Hideyuki; Aoki, Wako; Honda, Satoshi; Ando, Hiroyasu; Takada-Hidai, Masahide; Kambe, Eiji; Kawanomoto, Satoshi; Sadakane, Kozo; Sato, Bun'ei; Tajitsu, Akito; Tanaka, Wataru; Okita, Ki'ichi; Watanabe, Etsuji; Yoshida, Michitoshi

    2008-01-01

    Balmer and Paschen continuum emission as well as Balmer series lines of P Cygni-type profile from H_gamma through H_23 are revealed in the violet spectra of BM Gem, a carbon star associated with an oxygen-rich circumstellar shell (`silicate carbon star') observed with the high dispersion spectrograph (HDS) on the Subaru telescope. The blue-shifted absorption in the Balmer lines indicates the presence of an outflow, the line of sight velocity of which is at least 400 km s^-1, which is the highest outflow velocity observed to date in a carbon star. We argue that the observed unusual features in BM Gem are strong evidence for the presence of a companion, which should form an accretion disk that gives rise to both an ionized gas region and a high velocity, variable outflow. The estimated luminosity of ~0.2 (0.03-0.6) L_sun for the ionized gas can be maintained by a mass accretion rate to a dwarf companion of ~10^-8 M_sun yr^-1, while ~10^-10 M_sun yr^-1 is sufficient for accretion to a white dwarf companion. Thes...

  6. Trace elemental analysis of Indian natural moonstone gems by PIXE and XRD techniques.

    Science.gov (United States)

    Venkateswara Rao, R; Venkateswarulu, P; Kasipathi, C; Sivajyothi, S

    2013-12-01

    A selected number of Indian Eastern Ghats natural moonstone gems were studied with a powerful nuclear analytical and non-destructive Proton Induced X-ray Emission (PIXE) technique. Thirteen elements, including V, Co, Ni, Zn, Ga, Ba and Pb, were identified in these moonstones and may be useful in interpreting the various geochemical conditions and the probable cause of their inceptions in the moonstone gemstone matrix. Furthermore, preliminary XRD studies of different moonstone patterns were performed. The PIXE technique is a powerful method for quickly determining the elemental concentration of a substance. A 3MeV proton beam was employed to excite the samples. The chemical constituents of moonstones from parts of the Eastern Ghats geological formations of Andhra Pradesh, India were determined, and gemological studies were performed on those gems. The crystal structure and the lattice parameters of the moonstones were estimated using X-Ray Diffraction studies, trace and minor elements were determined using the PIXE technique, and major compositional elements were confirmed by XRD. In the present work, the usefulness and versatility of the PIXE technique for research in geo-scientific methodology is established.

  7. ORANGE: A high sensitivity particle tracker based on optically read out GEM

    Science.gov (United States)

    Marafini, M.; Patera, V.; Pinci, D.; Sarti, A.; Sciubba, A.; Spiriti, E.

    2017-02-01

    GEM-based detectors had a noticeable development in last years and have successfully been employed in different fields from High Energy Physics to imaging applications. Light production associated to the electron multiplication allows to perform an optical readout of these devices. The big progress achieved in CMOS-based photosensors makes possible to develop a high sensitivity, high granularity and low noise readout. In this paper we present the results obtained by reading out the light produced by a triple-GEM structure by means of a 4 mega-pixel CMOS sensor having a noise level less than two photons per pixel. The choice of a CF4 rich gas mixture (He/CF4 60/40) and a detailed optimisation of the electric fields allowed to reach a light-yield high enough to obtain very visible signals from minimum ionizing particles. In a test performed with 450 MeV electron beam, 800 photons per millimeter were collected and a space resolution of about 75 μ m was obtained.

  8. Fast triggering of high-rate charged particles with a triple-GEM detector

    CERN Document Server

    Alfonsi, M; Bonivento, W; Cardini, A; De Simone, P; Murtas, F; Pinci, D; Poli-Lener, M; Raspino, D

    2004-01-01

    A 3 year long R&D activity on triple gas electron multiplier (GEM) detectors is reported. This activity was made in the framework of the LHCb experiment in order to find the technology to instrument the central region of the first muon station (M1R1) where a high particle rate is expected. Detector geometry, gas mixture and electric field configuration have been optimized in order to achieve the performance required by the experiment. The use of a very fast, CF//4 based, gas mixture provides a time resolution of about 4.5 ns (r.m.s.) with a single chamber with gain less than 10**4. In addition, an optimized gain sharing between the three GEMs allows to keep the discharge probability per incident hadron below $10^{-12}$. The average number of firing pads per crossing particle have been found to be lower than 1.2. In a global aging test two detectors were exposed to a dose rate of 16 Gy/h. Each detector integrated about 2 C/cm**2 equivalent to more than 10 years of operation at LHCb. Good aging properties w...

  9. Morbidity Profile of Child Labor at Gem Polishing Units of Jaipur, India

    Directory of Open Access Journals (Sweden)

    RR Tiwari

    2014-07-01

    Full Text Available Background: There are millions of working children worldwide. Several causes are suggested for this social evil of which poverty plays a significant role in whether a child will work.Objective: To determine the morbidity profile in the working children of gem polishing units of Jaipur, India and assess some of its associated socio-economic factors.Methods: The present cross-sectional study included 586 gem polishing working children. Using interview, the demographic characteristics, occupational and clinical history of participants were recorded. The reason for taking up the job, income from the job and their desire to attend the school were also asked to assess the social causes of child labor in this region.Results: The mean±SD age of the working children was 11.3±5.3 years. In most of the instances, parents compelled the child to take up the job. Supposed to increase the family income substantially, the child labor activity failed to do so. On the other hand, the children suffered from several occupational health problems like eyestrain, headache, gastrointestinal complaints (eg, abdominal pain, nausea, vomiting, and diarrhea, musculoskeletal symptoms (eg, back pain, pain in limbs, neck pain, and joint pains and skin diseases (eg, scabies, dermatitis.Conclusion: It seems that the social factors forcing the children to work in the studied region, result in deterioration of their health and affect their growth.

  10. The Shape of Long Outbursts in U Gem Type Dwarf Novae from AAVSO Data

    Science.gov (United States)

    Cannizzo, John K.

    2012-01-01

    We search the American Association of Variable Star Observers (AAVSO) archives of the two best studied dwarf novae in an attempt to find light curves for long out bursts that are extremely well-characterized. The systems are U Gem and S8 Cyg. Our goal is to search for embedded precursors such as those that have been found recently in the high fidelity Kepler data for superoutbursts of some members of the 8U UMa subclass of dwarf novae. For the vast majority of AAV80 data, the combination of low data cadence and large errors associated with individual measurements precludes one from making any strong statement about the shape of the long outbursts. However, for a small number of outbursts, extensive long term monitoring with digital photometry yields high fidelity light curves. We report the finding of embedded precursors in two of three candidate long outbursts. This reinforces van Paradijs' finding that long outbursts in dwarf novae above the period gap and superoutbursts in systems below the period gap constitute a unified class. The thermal-tidal instability to account for superoutbursts in the SU UMa stars predicts embedded precursors only for short orbital period dwarf novae, therefore the presence of embedded precursors in long orbital period systems - U Gem and SS Cyg - argues for a more general mechanism to explain long outbursts.

  11. Erhöhter oxidativer Streß bei Patienten mit instabiler Angina pectoris

    Directory of Open Access Journals (Sweden)

    Bodlaj G

    1998-01-01

    Full Text Available Die instabile Angina pectoris führt oft zum akuten Myokardinfarkt. Da die Lipid-Peroxidation im Verdacht steht, chronische und akute Ereignisse der Atherosklerose und der koronaren Herzkrankheit zu fördern, untersuchten wir die Lipid-Peroxidations-Parameter und alpha-Toco-pherol-Spiegel bei 100 KHK-Patienten und verglichen sie mit denen einer entprechenden Kontrollgruppe. 50 konsekutive Patienten mit stabiler Angina pectoris (SAP und 50 konsekutive Patienten mit instabiler Angina pectoris (IAP wurden untersucht und mit 100 klinisch gesunden Personen verglichen. Zusätzlich zur herkömmlichen Lipid- und Lipoprotein-Analyse wurden die Lipid-Peroxidations-Produkte als Hydroperoxide und Thiobarbituric acid reactive substances (TBARS gemessen. Die konjugierten Diene wurden nur bei den Patienten bestimmt. Da alpha-Tocopherol eines der wichtigsten Antioxidantien ist, wurde es ebenfalls quantifiziert. Wie erwartet hatten die Patienten wesentlich höhere Cholesterin-, Triglyzerid-, LDL-C- und Lp(a-Spiegel und niedrigere HDL-C-Spiegel als die Kontrollgruppe. Als die Patienten in Gruppen mit stabiler und instabiler Angina pectoris geteilt wurden, waren Peroxide und TBARS in der letzteren Gruppe wesentlich höher als bei den anderen Patienten und der Kontrollgruppe. Auch konjugierte Diene waren eindeutig höher bei den Patienten mit instabiler Angina pectoris. Der alpha-Tocopherol-Gesamtspiegel war in allen 3 Gruppen vergleichbar, aber der alpha-Tocopherol-Gehalt pro LDL-Partikel war bei den Patienten mit IAP am niedrigsten, gefolgt von denen mit SAP und der Kontrollgruppe. Wir schließen daraus, daß die Lipid-Peroxidations-Parameter bei Patienten mit IAP erhöht sind und SAP-Patienten von IAP-Patienten unterscheiden.

  12. Kombinierte radiologisch-interventionelle und radiotherapeutische Behandlung von Patienten mit zentralen Gallengangsmalignomen

    Directory of Open Access Journals (Sweden)

    Riedmann E

    2005-01-01

    Full Text Available Einleitung: In einer retrospektiven Analyse von 24 Patienten mit inoperablen oder nicht radikal resezierten Karzinomen des Gallentraktes wurde der Einfluß einer HDR-(high-dose-rate192-Ir-Brachytherapie oder der kombinierten Tele-/Brachytherapie auf Überlebenszeit und Verbesserung der Lebensqualität untersucht. Methode und Material: Von 1996 bis 2001 wurden 24 Patienten mit einem Karzinom, welches die extrahepatischen Gallenwege obstruierte (16 Klatskin-Tumoren, 6 Gallenblasenkarzinome, 2 Metastasen eines GI-Tumors, einer palliativen Radiatio unterzogen. 14 von 24 Patienten wurden bei einem lokal fortgeschrittenen inoperablen Tumor, 5 Patienten nach einer R1-Resektion und 5 Patienten im Rezidiv behandelt. Bei allen Patienten wurde eine perkutane transhepatische Cholangiographie (PTC und anschließend die Implantation eines oder mehrerer selbstexpandierbarer Stents zur Behandlung der biliären Okklusion durchgeführt. 23 Patienten erhielten eine endoluminale Brachytherapie, 10 davon kombiniert mit einer Teletherapie; ein Patient erhielt eine alleinige Teletherapie. Im ersten Jahr wurde sechs Patienten die Brachytherapie mit einer Dosis von 15 Gray (Gy in drei Fraktionen verabreicht. Ab 1997 wurden 17 Patienten mit hyperfraktionierter Brachytherapie (2 x täglich mit einer mittleren Dosis von 20 Gy (5 x 4 Gy behandelt. Die mittlere Dosis der Teletherapie in beiden Gruppen betrug 40 Gy (Range 22–60 Gy. Ergebnisse: Das mediane Überleben für alle Patienten betrug 7,7 Monate. Patienten, die mit hyperfraktionierter Brachytherapie behandelt wurden, zeigten einen Trend zu einem verlängerten Überleben mit 11,6 Monaten verglichen mit 5,7 Monaten in der konventionell behandelten Gruppe. Die akuten Nebenwirkungen waren moderat.

  13. Einfluss der operativen Behandlung auf die Entwicklung von Kindern mit nonsyndromaler Kraniosynostose

    OpenAIRE

    Azouz, J. (Jamila-Stephanie)

    2008-01-01

    Ziel der Studie war die Klärung der Frage, ob eine Operation die psychomotorische Entwicklung von Kindern mit nonsyndromaler Nahtsynostose positiv beeinflussen kann. Dafür wurde die Entwicklung von 52 operierten und nicht operierten Kindern untersucht. Die Entwicklungsdiagnostik wurde mit Hilfe des ET 6-6 zum Zeitpunkt der Erstdiagnostik, 0 bis 6 sowie 6 bis 12 Monate nach der Operation durchgeführt. Zunächst wurden die Daten der operierten mit denen der nicht operierten Kinder verglichen. In...

  14. MAC GEMS

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Lion系统新添加的功能令人耳目一新,用户界面也有了很大的改动.然而有些用户却并不习惯Lion带来的新界面。好在通过系统偏好设置、终端或者第三方插件,就能很容易改Lion的界面。LionWeaks是一款简单的插件.它在一个独立窗口中提供了许多Lion版本的修改项,允许用户通过点击按钮更改某些设置。

  15. Anwendungsbeobachtungen mit Zolmitriptan-Rapilmet in der Praxis

    Directory of Open Access Journals (Sweden)

    Wessely P

    2004-01-01

    Full Text Available Nach Darstellungen der Prinzipien der evidenzbasierten Therapie (EBM der Migräneattacken wird die besondere Bedeutung der Triptane hervorgehoben. Die Entscheidung, Triptane einzusetzen, wird nicht unter Anwendung einer starren stufenweisen Verordnung, sondern flexibel anhand von Entscheidungshilfen für eine stratifizierte Therapieplanung getroffen. Eine solche Hilfe ist z. B. der in den USA entwickelte MIDAS-Fragebogen, der übersichtlich und einfach den Gesamtkomplex der Migräne erfaßt und nicht nur den Kopfschmerz, sondern auch die begleitenden autonomen Phänomene und vor allem auch die Beeinträchtigungen im sozio-ökonomischen Formenkreis bewertet. Dadurch kann die individuell erforderliche Therapieintensität, also z. B. der Einsatz von Triptanen, einfacher abgeschätzt werden. Die vorliegende Studie ist eine offene Anwendungsbeobachtung von Zolmitriptan-Rapimelt bei 349 Migränepatienten unter Verwendung des MIDAS-Fragebogens. Nach dreimonatiger Therapie konnte eine globale Besserung im Bereich der MIDAS-Scores nachgewiesen werden, wobei der Schweregrad IV von 42,7 % auf 14,6 % abgenommen hat (insgesamt signifikant für die Verbesserung jeweils um einen MIDAS-Grad. Die Kopfschmerzfrequenz hat sich ebenfalls von 14,6 Kopfschmerztage auf 8,7 reduziert, ebenso die Intensität – gemessen auf einer VAS-Skala – von 7,3 auf 5,3. Die Nebenwirkungsrate lag unter 2 %, die subjektive Zufriedenheit mit der Gesamtwirksamkeit von Zolmitriptan-Lyotabletten wurde in der Beurteilung durch die Probanden von 49,9 % mit sehr gut und von 35,8 % als gut bewertet, lediglich 4,3 % befanden die Medikation als unzureichend. In der Behandlung von Migräneattacken läßt sich für Zolmitriptan-RM eine hohe Patientenakzeptanz und auch ein hohes Maß an Effektivität und Wirkkonsistenz nicht nur unter den strengen Kriterien einer klinischen Prüfung, sondern auch unter den Bedingungen der Alltagspraxis nachweisen.

  16. Synthesis and applications of gem-bis-phosphonates, powerful complexing agents of metals; Synthese et applications de composes gem-bisphosphonates, de puissants complexants de metaux

    Energy Technology Data Exchange (ETDEWEB)

    Lecercle, D

    2007-12-15

    This thesis was devoted to the development of new ways to prepare gem-bis-phosphonates compounds (BPs), and was carried out under the Program of Nuclear and Environmental Toxicology (ToxNuc-E). Two applications of these compounds have been investigated, the preparation of potent ligands of the uranyl ion for a target of decorporation, and the preparation of new anticancer compounds. The first of these applications was the consequence of work done in the laboratory, that have shown the strong uranium-binding properties of bis-phosphonic ligands. The in vivo tests performed on these compounds have shown the tendency of these ligands to cause liver accumulation of uranium, we wanted to address this problem by modifying the method of anchoring of the bis-phosphonates functions. To this end we have developed a new way to access to these compounds using a metal-carbenoid mediated poly-ols and poly-amines insertion, the metal-carbenoid species bearing the bis-phosphonate function. Regarding the preparation of BPs as anticancer agents, we have developed a new synthetic pathway using a phosphine catalyzed {alpha}-P addition of phosphorated pro-nucleophiles to alkynyl-phosphonates as a key step. This enabled us to prepare thirty compound whose activity was evaluated on two cell lines (A431 and HuH7). Five of these compounds possess an activity equivalent to that of the compound described as the most active, the Zoledronate. (author)

  17. Gem1 and ERMES Do Not Directly Affect Phosphatidylserine Transport from ER to Mitochondria or Mitochondrial Inheritance

    DEFF Research Database (Denmark)

    Nguyen, Tammy T; Lewandowska, Agnieszka; Choi, Jae-Yeon;

    2012-01-01

    a primary role for ERMES in mitochondrial association with actin and mitochondrial movement. Finally, we show that ERMES complexes are long-lived, and do not depend on the presence of Gem1. Our findings suggest that the ERMES complex may have primarily a structural role in maintaining mitochondrial...

  18. The Germplasm Enhancement of Maize (GEM) project: A Public-Private Partnership (PPP) to increase genetic diversity in US maize

    Science.gov (United States)

    The Germplasm Enhancement of Maize (GEM) Project is a mission-oriented, cooperative research effort of the United States Department of Agriculture – Agricultural Research Service (USDA-ARS), land grant universities, private industry, and international agricultural research centers to broaden the ger...

  19. Tapping the Source: A Listing of Groundwater Education Materials Available through the Groundwater Education in Michigan (GEM) Program. Updated.

    Science.gov (United States)

    Michigan State Univ., East Lansing. Inst. of Water Research.

    Established in 1988 through the cooperative efforts of the Institute of Water Research at Michigan State University and the W. K. Kellogg Foundation, the Groundwater Education in Michigan (GEM) program helps people understand the relationship between their actions and the quality of their environment, particularly groundwater. The program has a…

  20. Building a large-area GEM-based readout chamber for the upgrade of the ALICE TPC

    CERN Document Server

    Gasik, Piotr

    2016-01-01

    A large Time Projection Chamber (TPC) is the main device for tracking and charged-particle identification in the ALICE experiment at the CERN LHC. After the second long shutdown in 2019-2020, the LHC will deliver Pb beams colliding at an interaction rate up to 50 kHz, which is about a factor of 100 above the present read-out rate of the TPC. To fully exploit the LHC potential the TPC will be upgraded based on the Gas Electron Multiplier (GEM) technology. A prototype of an ALICE TPC Outer Read-Out Chamber (OROC) was equipped with twelve large-size GEM foils as amplification stage to demonstrate the feasibility of replacing the current Multi Wire Proportional Chambers with the new technology. With a total area of $\\sim$0.76 m$^2$ it is the largest GEM-based detector built to date. The GEM OROC was installed within a test field cage and commissioned with radioactive sources.

  1. Short-term H{\\alpha} line variations in Classical Be stars: 59 Cyg and OT Gem

    CERN Document Server

    KT, Paul; Subramaniam, Annapurni

    2016-01-01

    We present the optical spectroscopic study of two Classical Be stars, 59 Cyg and OT Gem obtained over a period of few months in 2009. We detected a rare triple-peak H$\\alpha$ emission phase in 59 Cyg and a rapid decrease in the emission strength of H$\\alpha$ in OT Gem, which are used to understand their circumstellar disks. We find that 59 Cyg is likely to be rapid rotator, rotating at a fractional critical rotation of $\\sim$ 0.80. The radius of the H$\\alpha$ emission region for 59 Cyg is estimated to be $R_d/R_*$ $\\sim$ 10.0, assuming a Keplerian disk, suggesting that it has a large disk. We classify stars which have shown triple-peaks into two groups and find that the triple-peak emission in 59 Cyg is similar to $\\zeta$ Tau. OT Gem is found to have a fractional critical rotation of $\\sim$ 0.30, suggesting that it is either a slow rotator or viewed in low inclination. In OT Gem, we observed a large reduction in the radius of the H$\\alpha$ emission region from $\\sim$ 6.9 to $\\sim$ 1.7 in a period of three mon...

  2. Girls in Engineering, Mathematics and Science, GEMS: A Science Outreach Program for Middle-School Female Students

    Science.gov (United States)

    Dubetz, Terry A.; Wilson, Jo Ann

    2013-01-01

    Girls in Engineering, Mathematics and Science (GEMS) is a science and math outreach program for middle-school female students. The program was developed to encourage interest in math and science in female students at an early age. Increased scientific familiarity may encourage girls to consider careers in science and mathematics and will also help…

  3. Characterization of a GEM-based scintillation detector with He-CF4 gas mixture in clinical proton beams

    Science.gov (United States)

    Nichiporov, D.; Coutinho, L.; Klyachko, A. V.

    2016-04-01

    Accurate, high-spatial resolution dosimetry in proton therapy is a time consuming task, and may be challenging in the case of small fields, due to the lack of adequate instrumentation. The purpose of this work is to develop a novel dose imaging detector with high spatial resolution and tissue equivalent response to dose in the Bragg peak, suitable for beam commissioning and quality assurance measurements. A scintillation gas electron multiplier (GEM) detector based on a double GEM amplification structure with optical readout was filled with a He/CF4 gas mixture and evaluated in pristine and modulated proton beams of several penetration ranges. The detector’s performance was characterized in terms of linearity in dose rate, spatial resolution, short- and long-term stability and tissue-equivalence of response at different energies. Depth-dose profiles measured with the GEM detector in the 115-205 MeV energy range were compared with the profiles measured under similar conditions using the PinPoint 3D small-volume ion chamber. The GEM detector filled with a He-based mixture has a nearly tissue equivalent response in the proton beam and may become an attractive and efficient tool for high-resolution 2D and 3D dose imaging in proton dosimetry, and especially in small-field applications.

  4. Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes

    KAUST Repository

    Wang, Fei

    2011-01-01

    A chloride ion-catalyzed generation of difluorocarbene from a relatively non-toxic and inexpensive precursor, Me3SiCF2Cl (1), under mild and neutral conditions leads to an efficient preparation of gem-difluorocyclopropenes and difluorocyclopropanes through [2 + 1] cycloaddition reactions with alkynes and alkenes, respectively. © 2011 The Royal Society of Chemistry.

  5. Performance of a Large-Area GEM Detector Prototype for the Upgrade of the CMS Muon Endcap System

    CERN Document Server

    Abbaneo, D.; Abbrescia, M.; Abdelalim, A.A.; Abi Akl, M.; Ahmed, W.; Ahmed, W.; Altieri, P.; Aly, R.; Asawatangtrakuldee, C.; Ashfaq, A.; Aspell, P.; Assran, Y.; Awan, I.; Bally, S.; Ban, Y.; Banerjee, S.; Barria, P.; Benussi, L.; Bhopatkar, V.; Bianco, S.; Bos, J.; Bouhali, O.; Braibant, S.; Buontempo, S.; Calabria, C.; Caponero, M.; Caputo, C.; Cassese, F.; Castaneda, A.; Cauwenbergh, S.; Cavallo, F.R.; Celik, A.; Choi, M.; Choi, K.; Choi, S.; Christiansen, J.; Cimmino, A.; Colafranceschi, S.; Colaleo, A.; Conde Garcia, A.; Dabrowski, M.M.; De Lentdecker, G.; de Oliveira, R.; De Robertis, G.; Dildick, S.; Dorney, B.; Elmetenawee, W.; Fabrice, G.; Ferrini, M.; Ferry, S.; Giacomelli, P.; Gilmore, J.; Guiducci, L.; Gutierrez, A.; Hadjiiska, R.M.; Hassan, A.; Hauser, J.; Hoepfner, K.; Hohlmann, M.; Hoorani, H.; Jeng, Y.G.; Kamon, T.; Karchin, P.E.; Kim, H.S.; Krutelyov, S.; Kumar, A.; Lee, J.; Lenzi, T.; Litov, L.; Loddo, F.; Maerschalk, T.; Magazzu, G.; Maggi, M.; Maghrbi, Y.; Magnani, A.; Majumdar, N.; Mal, P.K.; Mandal, K.; Marchioro, A.; Marinov, A.; Merlin, J.A.; Mohanty, A.K.; Mohapatra, A.; Muhammad, S.; Mukhopadhyay, S.; Naimuddin, M.; Nuzzo, S.; Oliveri, E.; Pant, L.M.; Paolucci, P.; Park, I.; Passeggio, G.; Pavlov, B.; Philipps, B.; Phipps, M.; Piccolo, D.; Postema, H.; Pugliese, G.; Baranac, A.Puig; Radi, A.; Radogna, R.; Raffone, G.; Ramkrishna, S.; Ranieri, A.; Riccardi, C.; Rodrigues, A.; Ropelewski, L.; RoyChowdhury, S.; Ryu, M.S.; Ryu, G.; Safonov, A.; Sakharov, A.; Salva, S.; Saviano, G.; Sharma, A.; Swain, S.K.; Talvitie, J.P.; Tamma, C.; Tatarinov, A.; Turini, N.; Tuuva, T.; Twigger, J.; Tytgat, M.; Vai, I.; van Stenis, M.; Venditi, R.; Verhagen, E.; Verwilligen, P.; Vitulo, P.; Wang, D.; Wang, M.; Yang, U.; Yang, Y.; Yonamine, R.; Zaganidis, N.; Zenoni, F.; Zhang, A.

    2014-01-01

    Gas Electron Multiplier (GEM) technology is being considered for the forward muon upgrade of the CMS experiment in Phase 2 of the CERN LHC. Its first implementation is planned for the GE1/1 system in the $1.5 < \\mid\\eta\\mid < 2.2$ region of the muon endcap mainly to control muon level-1 trigger rates after the second long LHC shutdown. A GE1/1 triple-GEM detector is read out by 3,072 radial strips with 455 $\\mu$rad pitch arranged in eight $\\eta$-sectors. We assembled a full-size GE1/1 prototype of 1m length at Florida Tech and tested it in 20-120 GeV hadron beams at Fermilab using Ar/CO$_{2}$ 70:30 and the RD51 scalable readout system. Four small GEM detectors with 2-D readout and an average measured azimuthal resolution of 36 $\\mu$rad provided precise reference tracks. Construction of this largest GEM detector built to-date is described. Strip cluster parameters, detection efficiency, and spatial resolution are studied with position and high voltage scans. The plateau detection efficiency is [97.1 $\\pm...

  6. Strong Variable Ultraviolet Emission from Y Gem: Accretion Activity in an AGB Star with a Binary Companion?

    CERN Document Server

    Sahai, Raghvendra; de Paz, Armando Gil; Contreras, Carmen Sánchez

    2011-01-01

    Binarity is believed to dramatically affect the history and geometry of mass loss in AGB and post-AGB stars, but observational evidence of binarity is sorely lacking. As part of a project to look for hot binary companions to cool AGB stars using the GALEX archive, we have discovered a late-M star, Y Gem, to be a source of strong and variable UV emission. Y Gem is a prime example of the success of our technique of UV imaging of AGB stars in order to search for binary companions. Y Gem's large and variable UV flux makes it one of the most prominent examples of a late AGB star with a mass accreting binary companion. The UV emission is most likely due to emission associated with accretion activity and a disk around a main-sequence companion star. The physical mechanism generating the UV emission is extremely energetic, with an integrated luminosity of a few L(sun) at its peak. We also find weak CO J=2-1 emission from Y Gem with a very narrow line profile (FWHM of 3.4 km/s). Such a narrow line is unlikely to arise...

  7. Development of the DAQ System of Triple-GEM Detectors for the CMS Muon Spectrometer Upgrade at LHC

    CERN Document Server

    AUTHOR|(INSPIRE)INSPIRE-00387583

    The Gas Electron Multiplier (GEM) upgrade project aims at improving the performance of the muon spectrometer of the Compact Muon Solenoid (CMS) experiment which will suffer from the increase in luminosity of the Large Hadron Collider (LHC). After a long technical stop in 2019-2020, the LHC will restart and run at a luminosity of 2 × 1034 cm−2 s−1, twice its nominal value. This will in turn increase the rate of particles to which detectors in CMS will be exposed and affect their performance. The muon spectrometer in particular will suffer from a degraded detection efficiency due to the lack of redundancy in its most forward region. To solve this issue, the GEM collaboration proposes to instrument the first muon station with Triple-GEM detectors, a technology which has proven to be resistant to high fluxes of particles. Within the GEM collaboration, the Data Acquisition (DAQ) subgroup is in charge of the development of the electronics and software of the DAQ system of the detectors. This thesis presents th...

  8. Building a large-area GEM-based readout chamber for the upgrade of the ALICE TPC

    Science.gov (United States)

    Gasik, P.

    2017-02-01

    A large Time Projection Chamber (TPC) is the main device for tracking and charged-particle identification in the ALICE experiment at the CERN LHC. After the second long shutdown in 2019-2020, the LHC will deliver Pb beams colliding at an interaction rate up to 50 kHz, which is about a factor of 100 above the present read-out rate of the TPC. To fully exploit the LHC potential the TPC will be upgraded based on the Gas Electron Multiplier (GEM) technology. A prototype of an ALICE TPC Outer Read-Out Chamber (OROC) was equipped with twelve large-size GEM foils as amplification stage to demonstrate the feasibility of replacing the current Multi Wire Proportional Chambers with the new technology. With a total area of ∼0.76 m2 it is the largest GEM-based detector built to date. The GEM OROC was installed within a test field cage and commissioned with radioactive sources.

  9. Test beam studies of Gas Electron Multiplier (GEM) detectors for the upgrade of CMS endcap muon system

    CERN Document Server

    Sharma, Ram Krishna

    2017-01-01

    The High Luminosity LHC (HL-LHC) will provide exceptional high instantaneous and integrated luminosity. The forward region $\\mid \\eta \\mid \\geq 1.5$ of the CMS detector will face extremely high particle rates in tens of $KHz/cm^{2}$ and hence it will affect the momentum resolution and longevity of the muon detectors. To overcome these issues the CMS collaboration has decided to install new large size rate capable Triple Gas Electron Multiplier (GEM) detectors in the forward region of CMS muon system. The first set of Triple GEM detectors will be installed in the GE1/1 region $(1.5 \\leq \\eta \\leq 2.2)$ of muon endcap during the LS2 of the LHC and the next one will be installed in the GE2/1 region $(1.6 \\leq \\eta \\leq 2.5)$, during the LS3. Towards this goal, full-size CMS Triple GEM prototype chambers have been fabricated and put under the test beam at the CERN SPS test beam facility. The GEM detectors were operated with two gas mixtures $Ar/CO_{2}$ (70/30) and $Ar/CO_{2}/CF_{4}$ (40/15/45). In 2014 and 2016, ...

  10. Educational Outreach at the MIT Plasma Science and Fusion Center

    Science.gov (United States)

    Rivenberg, Paul; Thomas, Paul

    2006-10-01

    At the MIT PSFC, student and staff volunteers work together to increase the public's knowledge of fusion science and plasma technology. Seeking to generate excitement in young people about science and engineering, the PSFC hosts a number of educational outreach activities throughout the year, including Middle and High School Outreach Days. The PSFC also has an in-school science demonstration program on the theme of magnetism. The Mr. Magnet Program, headed by Mr. Paul Thomas, has been bringing lively demonstrations on magnetism into local elementary and middle schools for 15 years. This year Mr. Magnet presented the program to nearly 30,000 students at over 67 schools and other events, reaching kindergartners through college freshmen. In addition to his program on magnetism, he is offering an interactive lecture about plasma to high schools. The "Traveling Plasma Lab" encourages students to learn more about plasma science while having fun investigating plasma properties using actual laboratory techniques and equipment. Beyond the classroom, Paul Thomas has provided technical training for Boston Museum of Science staff in preparation for the opening of a Star Wars exhibit. His hands-on demos have also been filmed by the History Channel for a one-hour program about Magnetism, which aired in June 2006.

  11. Oxygen isotope systematics of gem corundum deposits in Madagascar: relevance for their geological origin

    Science.gov (United States)

    Giuliani, Gaston; Fallick, Anthony; Rakotondrazafy, Michel; Ohnenstetter, Daniel; Andriamamonjy, Alfred; Ralantoarison, Théogène; Rakotosamizanany, Saholy; Razanatseheno, Marie; Offant, Yohann; Garnier, Virginie; Dunaigre, Christian; Schwarz, Dietmar; Mercier, Alain; Ratrimo, Voahangy; Ralison, Bruno

    2007-02-01

    The oxygen isotopic composition of gem corundum was measured from 22 deposits and occurrences in Madagascar to provide a gemstone geological identification and characterization. Primary corundum deposits in Madagascar are hosted in magmatic (syenite and alkali basalt) and metamorphic rocks (gneiss, cordieritite, mafic and ultramafic rocks, marble, and calc-silicate rocks). In both domains the circulation of fluids, especially along shear zones for metamorphic deposits, provoked in situ transformation of the corundum host rocks with the formation of metasomatites such as phlogopite, sakenite, and corundumite. Secondary deposits (placers) are the most important economically and are contained in detrital basins and karsts. The oxygen isotopic ratios (18O/16O) of ruby and sapphire from primary deposits are a good indicator of their geological origin and reveal a wide range of δ18O (Vienna Standard Mean Ocean Water) between 1.3 and 15.6‰. Metamorphic rubies are defined by two groups of δ18O values in the range of 1.7 to 2.9‰ (cordieritite) and 3.8 to 6.1‰ (amphibolite). “Magmatic” rubies from pyroxenitic xenoliths contained in the alkali basalt of Soamiakatra have δ18O values ranging between 1.3 and 4.7‰. Sapphires are classified into two main groups with δ18O in the range of 4.7 to 9.0‰ (pyroxenite and feldspathic gneiss) and 10.7 to 15.6‰ (skarn in marble from Andranondambo). The δ18O values for gem corundum from secondary deposits have a wide spread between -0.3 and 16.5‰. The ruby and sapphire found in placers linked to alkali basalt environments in the northern and central regions of Madagascar have consistent δ18O values between 3.5 and 6.9‰. Ruby from the placers of Vatomandry and Andilamena has δ18O values of 5.9‰, and between 0.5 and 4.0‰, respectively. The placers of the Ilakaka area are characterized by a huge variety of colored sapphires and rubies, with δ18O values between -0.3 and 16.5‰, and their origin is debated. A

  12. Application of the GEM Inventory Data Capture Tools for Dynamic Vulnerability Assessment and Recovery Modelling

    Science.gov (United States)

    Verrucci, Enrica; Bevington, John; Vicini, Alessandro

    2014-05-01

    A set of open-source tools to create building exposure datasets for seismic risk assessment was developed from 2010-13 by the Inventory Data Capture Tools (IDCT) Risk Global Component of the Global Earthquake Model (GEM). The tools were designed to integrate data derived from remotely-sensed imagery, statistically-sampled in-situ field data of buildings to generate per-building and regional exposure data. A number of software tools were created to aid the development of these data, including mobile data capture tools for in-field structural assessment, and the Spatial Inventory Data Developer (SIDD) for creating "mapping schemes" - statistically-inferred distributions of building stock applied to areas of homogeneous urban land use. These tools were made publically available in January 2014. Exemplar implementations in Europe and Central Asia during the IDCT project highlighted several potential application areas beyond the original scope of the project. These are investigated here. We describe and demonstrate how the GEM-IDCT suite can be used extensively within the framework proposed by the EC-FP7 project SENSUM (Framework to integrate Space-based and in-situ sENSing for dynamic vUlnerability and recovery Monitoring). Specifically, applications in the areas of 1) dynamic vulnerability assessment (pre-event), and 2) recovery monitoring and evaluation (post-event) are discussed. Strategies for using the IDC Tools for these purposes are discussed. The results demonstrate the benefits of using advanced technology tools for data capture, especially in a systematic fashion using the taxonomic standards set by GEM. Originally designed for seismic risk assessment, it is clear the IDCT tools have relevance for multi-hazard risk assessment. When combined with a suitable sampling framework and applied to multi-temporal recovery monitoring, data generated from the tools can reveal spatio-temporal patterns in the quality of recovery activities and resilience trends can be

  13. Genotyp-/Phänotyp-Analyse und klinische Charakterisierung von 25 Familien mit familiärer Hypomagnesiämie mit Hyperkalziurie und Nephrokalzinose

    OpenAIRE

    Schneider, Linda

    2010-01-01

    Die familiäre Hypomagnesiämie mit Hyperkalziurie und Nephrokalzinose (FHHNC) ist eine autosomal rezessive renal-tubuläre Erkrankung, die häufig mit progredientem Nierenversagen assoziiert ist. Der primäre Defekt besteht in einer gestörten tubulären Reabsorption von Magnesium und Kalzium im dicken aufsteigenden Teil der Henle-Schleife (TAL) der Niere. Mutationen im CLDN16-Gen (früher PCLN1-Gen), welches für das renale Tight Junctio...

  14. Entwicklung und Evaluation eines psychoedukativen Elterngruppen-Trainingsprogramms für Familien mit autistischen Kindern

    OpenAIRE

    Probst, Paul

    2003-01-01

    In der Einleitung wird das Konzept des "Psychoedukativen Elterntrainings" erläutert und ein Überblick über den Forschungsstand zum Thema "Elterntraining in Familien mit autistischen Kindern" gegeben. Ausgehend von dieser Analyse wurde ein psychoedukatives Eltern-Gruppentraining für Familien mit autistischen Kindern entwickelt und im Rahmen eines 3-Monate-Follow-up-Versuchsplans evaluiert. Die beiden Hauptziele des Trainingcurriculums waren "Vermittlung eines Konzepts über Wesen, Ursach...

  15. Toess weir with small power station Pfungen; Toesswehr mit Kleinkraftwerk Pfungen

    Energy Technology Data Exchange (ETDEWEB)

    Haerri, R.W. [Amt fuer Gewaesserschutz und Wasserbau, Abt. Gewaesserkorrektionen, Zurich (Switzerland)

    1995-12-31

    Near Pfungen on the River Toess the Canton of Zurich replaced a dilapidated weir and utilises the available falling gradient with a small power station. Besides the production of renewable energy the assistance of a fish ladder has been made available. (orig.) [Deutsch] Bei Pfungen an der Toess ersetzte der Kanton Zuerich ein baufaelliges Wehr und nutzt das vorhandene Gefaelle mit einem Kleinkraftwerk. Neben der Erzeugung von erneuerbarer Energie kann nun mit Hilfe einer Treppe auch der Fischaufstieg gewaehrleistet werden. (orig.)

  16. eine randomisierte Studie an 200 Patienten mit Prostatae kleiner 100 g und urodynamisch nachgewiesener Obstruktion

    OpenAIRE

    Ahyai, Sascha A.

    2006-01-01

    Ziele: Trotz ihrer signifikanten Morbidität stellt die transurethrale Resektion der Prostata (TURP) den gold standard dar für die instrumentelle Therapie der durch die benigne Prostatahyperplasie (BPH) bedingten Blasenauslassobstruktion. Mit dem Hochleistungs-Holmium: YAG Laser kann endoskopisch, in einer relativ blutungsarmen Weise, Prostatagewebe enukleiert werden. Wir verglichen die Technik der transurethralen Holmium-Laser-Enukleation der Prostata (HoLEP) mit der Standard-TURP bei der ope...

  17. Die Ferse schmerzt: Behandlung des M. triceps surae bei Patienten mit Fasciitis plantaris : Ein systematisches Literaturreview

    OpenAIRE

    Brunner, Melanie

    2015-01-01

    Darstellung des Themas: Die Dehnung des M. triceps surae bei Patienten mit Fasciitis plantaris wird in der Literatur als begleitende Intervention empfohlen. Dies lässt einen Zusammenhang zwischen den Plantarflexoren und den Fersenschmerzen vermuten, weshalb die Untersuchung von weiteren Behandlungsmethoden am M. triceps surae von Bedeutung ist. Ziel: Das Ziel dieser Arbeit war, eine Aussage über die Effektivität von verschiedenen Behandlungsmethoden des M. triceps surae bei Patienten mit F...

  18. Analyse der T-Zellkreuzreaktivität bei Birkenpollenallergikern mit assoziierter Nahrungsmittelallergie

    OpenAIRE

    Hofmann, Claudia

    2014-01-01

    Eine Pollenallergie geht häufig mit einer sekundären Nahrungsmittelallergie einher, die durch die Kreuzreaktivität zwischen dem Pollen- und dem Nahrungsmittelallergen verursacht wird. In der vorliegenden Arbeit wurde eine Kohorte von 20 Allergikern mit einer Typ I-Allergie gegen Birkenpollen und einer assoziierten Nahrungsmittelallergie gegen Haselnüsse und/oder Karotten in Bezug auf eine allergenspezifische IgE-Antwort, T-Zellantwort und vor allen Dingen hinsichtlich der T-Zellkreuzreaktivit...

  19. Erfassung und Trainierbarkeit der posturalen Kontrolle und Modulation des Gangbildes bei Patienten mit Morbus Parkinson

    OpenAIRE

    2015-01-01

    Die vorliegende Arbeit gliedert sich in drei Teile. Zunächst geht es um die Erfassung der posturalen Instabilität bei Patienten mit Morbus Parkinson. Es wurde ein klinischer Gleichgewichtstest (Fullerton Advanced Balance (FAB) Scale) zur Erhebung der posturalen Kontrolle validiert und mit der Berg Balance Scale und dem Mini-Balance Evaluation System Test (Mini-BESTest) verglichen. Hierfür wurden 85 Parkinsonpatienten eingeschlossen und untersucht. Es konnte gezeigt werden, dass die FAB Sc...

  20. Biomechanische Untersuchungsergebnisse über die verbesserte Verankerung von Pedikelschrauben mit resorbierbarem

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Die Prim?rstabilit?t von Pedikelschrauben im Knochen h?ngt in hohem Masse von der Knochendichte ab. Die Augmentation mit Zement ist ein klinisch einsetzbares Verfahren, um die Schrauben-Verankerung im osteoporotischen Knochen zu verbessern.In dieser Studie wurde eine neuartiges resorbierbares Knochenersatzmaterial (α-BSMTM) für diese Augmentation benutzt. Biomechanische Testungen wurden in vitro bei 16 Lendwirbelkorpern (L3-L5) aus 6 Individuen(75,2±13,7 Jahre) durchgeführt. Vor der biomechanischen Testung wurde bei allen Pr?paraten die trabekul?re Knochendichte mittels pQCT gemessen und beide Pedikel mit USS-Pedikelschrauben (5,0 mm × 45 mm) besetzt, von welchen eine mit α-BSMTM augmentiert war. Beim axialen Auszugstest wurden die maximale axiale Auszugskraft (F-max) sowie die Energieaufnahme bestimmt. Der Medianwert der F-max stieg beim Auszugstest durch die Zementierung mit α-BSMTM um 80 % von 370 N (ohne Zement) auf 665 N (mit Zement). Die Energieaufnahme bis zum Erreichen der F-max (E-F-max) und bei Dislokation bis 2,0 mm (E-2 mm) steigerte sich ebenfalls um 83 % und 68 %. Die Unterschiede waren signifikant. (Wilcoxon′s-Test, P<0,01) Die Ausreisskrafte F-max (ohne oder mit Zement) korrelierten eng mit der Knochendichte (r=0,9056 und r=0,9585). Unsere Resultate zeigen, da eine Augmentation mit dem α-BSMTM die prim?re Stabilit?t von Pedikelschrauben verbessern kann. Der Effekt scheint auf einer Optimierung der Kontaktfl?che und einer Aussteifung der schraubennahen Spongiosa zu beruhen. Das Material konnte geeignet sein, die Verankerung von Pedikelschrauben bei osteoporotischen Patieten zu verbessern.

  1. Optische 3D-Messtechnik : Präzise Gestaltvermessung mit einem erweiterten Streifenprojektionsverfahren

    OpenAIRE

    Wiora, Georg

    2001-01-01

    Die Streifenprojektion mit zeitlich kodierten Beleuchtungsmustern hat sich nach ihrer Erfindung - trotz vorhandener Schwächen - schnell neben den, seit Jahrzehnten ausgereiften, mechanischen Koordinaten-Messmaschinen in der 3D-Messtechnik etabliert. Diese Arbeit stellt einen Beitrag zu ihrer Konsolidierung dar. Zur Abschätzung der Leistungsfähigkeit werden die Genauigkeitsgrenzen eines Streifenprojektionssystems mit einem neuen Ansatz theoretisch erfasst. Es wird ein Verfahren zur präzisen Be...

  2. Fondaparinux bei Herz-Kreislauf-Erkrankungen: Ein neues Antithrombin mit herausragenden Eigenschaften

    Directory of Open Access Journals (Sweden)

    Huber K

    2008-01-01

    Full Text Available Fondaparinux, ein synthetisches Pentasaccharid, führt zu einer indirekten Hemmung des Gerinnungsfaktors Xa und behindert in der Folge die Bildung von Thrombin. Fondaparinux wurde als Vergleichssubstanz gegenüber unfraktioniertem (Standard- Heparin oder dem niedermolekularen Heparin Enoxaparin in der Prophylaxe oder Therapie von venösen Thrombosen getestet. Zuletzt wurde Fondaparinux auch bei Patienten mit akuten Koronarsyndromen (ACS untersucht: bei Patienten mit ACS ohne ST-Hebung (NSTE-ACS waren sowohl die Blutungsrate als auch die Kurz- und Langzeitmortalität im Fondaparinuxarm (2,5 mg/Tag s. c. signifikant geringer als in den Enoxaparin-behandelten Patienten (1 mg/kg KG 2×/Tag s. c. (OASIS-5-Studie. Bei Patienten mit akutem ST-Strecken-Hebungsinfarkt (STEMI war Fondaparinux in den Subgruppen der konservativ behandelten Patienten (ohne Reperfusion und der Patienten, die eine pharmakologische Reperfusion erhielten (Thrombolyse von Vorteil gegenüber Placebo oder unfraktioniertem Heparin. Hingegen zeigte sich bei Patienten mit STEMI, die einer Akut-PCI unterzogen wurden, eine starke Tendenz zugunsten von unfraktioniertem Heparin gegenüber Fondaparinux (OASIS-6-Studie. Daher wird Fondaparinux in den internationalen Richtlinien als das Antithrombin mit der günstigsten Risiko/Nutzen-Ratio bei NSTEMI aber auch bei STEMI-Patienten mit Ausnahme jener Patienten, die sich einer Akut-PCI unterziehen, empfohlen. Fondaparinux könnte schon in der nahen Zukunft die Heparine in diesen Indikationen weitgehend ersetzen.

  3. Two-dimensional GEM imaging detector with delay-line readout

    Science.gov (United States)

    Guedes, G. P.; Breskin, A.; Chechik, R.; Vartsky, D.; Bar, D.; Barbosa, A. F.; Marinho, P. R. B.

    2003-11-01

    A 100×100 mm 2 2D imaging detector, based on a triple-GEM gaseous multiplier, striped x- y readout anode and discrete delay-line readout, is presented. The fast (2.1 ns tap -1) delay-line circuit was designed to match the anode-charge signal profile, namely its rise-time and length. The detector's imaging capability was systematically studied in Ar/CO 2 (70/30) with 5.9 keV X-rays; x- y resolution of σ=0.05 and 0.1 mm for top and bottom anode strips, respectively, and integral non-linearity of ˜0.15% are demonstrated.

  4. On Competitiveness of Agricultural Industrial Clusters in Hubei Province Based on GEM Model

    Institute of Scientific and Technical Information of China (English)

    CHEN De-gang

    2012-01-01

    Firstly, this paper summarizes concept of the agricultural industrial cluster and GEM model. Then, it analyzes the competitiveness of agricultural industrial clusters in Hubei Province from three aspects, namely, the foundation, enterprises and market. In the aspect of the foundation, Hubei Province has superior geographical location, rich natural resources, abundant human resources, diversified capital sources, and hardware and software facilities. In the aspect of enterprises, agricultural suppliers (farmers) are relatively scattered in Hubei Province, organizational level of relevant enterprises is constantly improved, and structure and strategy of enterprises are constantly innovated. In the aspect of market, the competition of agricultural products is fierce in local market, and it is difficult to explore external market. Finally, it presents countermeasures to improve the competitiveness of agricultural industrial clusters in Hubei Province, including building agricultural industrial park and cultivating key leading enterprises, strengthening innovation management, and increasing financial support.

  5. A cylindrical GEM detector with analog readout for the BESIII experiment

    Science.gov (United States)

    Amoroso, A.; Baldini, R.; Bertani, M.; Bettoni, D.; Bianchi, F.; Calcaterra, A.; Carassiti, V.; Cerioni, S.; Chai, J.; Cibinetto, G.; Cotto, G.; Mori, F. De; Destefanis, M.; Dong, J.; Dong, M.; Farinelli, R.; Fava, L.; Felici, G.; Fioravanti, E.; Garzia, I.; Gatta, M.; Greco, M.; Hu, J. F.; Johansson, T.; Leng, C.; Li, H.; Liu, Z.; Maggiora, M.; Marcello, S.; Marciniewski, P.; Melchiorri, M.; Mezzadri, G.; Morello, G.; Ouyan, Q.; Pacetti, S.; Patteri, P.; Rivetti, A.; Rosner, C.; Savrié, M.; Sosio, S.; Spataro, S.; Tskhadadze, E.; Wang, K.; Wang, L.; Wu, L.; Ji, X.; Ye, M.; Zallo, A.; Zhang, Y.; Zotti, L.

    2016-07-01

    A cylindrical GEM detector with analog readout is under development for the upgrade of the Inner Tracker of the BESIII experiment at IHEP (Beijing). The new detector will match the requirements for momentum resolution (σpt /pt ~ 0.5 % at 1 GeV) and radial resolution (σxy ~ 120 μm) of the existing drift chamber and will improve significantly the spatial resolution along the beam direction (σz ~ 150 μm) with very small material budget (less than 1.5% of X0). With respect to the state of the art the following innovations will be deployed: a lighter mechanical structure based on Rohacell, a new XV anode readout plane with jagged strip layout to reduce the parasitic capacitance, and the use of the analogue readout inside a high intensity magnetic field to have good spatial resolution without increasing the number of channels.

  6. Clumpy Galaxies in GOODS and GEMS: Massive Analogs of Local Dwarf Irregulars

    CERN Document Server

    Elmegreen, Debra Meloy; Marcus, Max T; Shahinyan, Karlen; Yau, Andrew; Petersen, Michael

    2009-01-01

    Clumpy galaxies in the GEMS and GOODS fields are examined for clues to their evolution into modern spirals. The magnitudes of the clumps and the surface brightnesses of the interclump regions are measured and fitted to models of stellar age and mass. There is an evolutionary trend from clump clusters with no evident interclump emission to clump clusters with faint red disks, to spiral galaxies of the flocculent or grand design types. Along this sequence, the interclump surface density increases and the mass surface density contrast between the clumps and the interclump regions decreases, suggesting a gradual dispersal of clumps to form disks. Also along this sequence, the bulge-to-clump mass ratios and age ratios increase, suggesting a gradual formation of bulges. All of these morphological types occur in the same redshift range, indicating that the clump cluster morphology is not the result of bandshifting. Comparisons to local galaxies with the same rest wavelength and spatial resolution show that clump clu...

  7. Design and optimization of resistive anode for a two-dimensional imaging GEM detector

    Science.gov (United States)

    Ju, Xu-Dong; Dong, Ming-Yi; Zhao, Yi-Chen; Zhou, Chuan-Xing; Qun, Ou-Yang

    2016-08-01

    A resistive anode for two-dimensional imaging detectors, which consists of a series of high resistivity pads surrounded by low resistivity strips, can provide good spatial resolution while reducing the number of electronics channels required. The optimization of this kind of anode has been studied by both numerical simulations and experimental tests. It is found that to obtain good detector performance, the resistance ratio of the pads to the strips should be larger than 5, the nonuniformity of the pad surface resistivity should be less than 20%, a smaller pad width leads to a smaller spatial resolution, and when the pad width is 6 mm, the spatial resolution (σ) can reach about 105 μm. Based on the study results, a 2-D GEM detector prototype with optimized resistive anode is constructed and a good imaging performance is achieved. Supported by National Natural Science Foundation of China (11375219) and CAS Center for Excellence in Particle Physics (CCEPP)

  8. C-4 Gem-Dimethylated Oleanes of Gymnema sylvestre and Their Pharmacological Activities

    Directory of Open Access Journals (Sweden)

    Giovanni Di Fabio

    2013-12-01

    Full Text Available Gymnema sylvestre R. Br., one of the most important medicinal plants of the Asclepiadaceae family, is a herb distributed throughout the World, predominantly in tropical countries. The plant, widely used for the treatment of diabetes and as a diuretic in Indian proprietary medicines, possesses beneficial digestive, anti-inflammatory, hypoglycemic and anti-helmentic effects. Furthermore, it is believed to be useful in the treatment of dyspepsia, constipation, jaundice, hemorrhoids, cardiopathy, asthma, bronchitis and leucoderma. A literature survey revealed that some other notable pharmacological activities of the plant such as anti-obesity, hypolipidemic, antimicrobial, free radical scavenging and anti-inflammatory properties have been proven too. This paper aims to summarize the chemical and pharmacological reports on a large group of C-4 gem-dimethylated pentacyclic triterpenoids from Gymnema sylvestre.

  9. C-4 gem-dimethylated oleanes of Gymnema sylvestre and their pharmacological activities.

    Science.gov (United States)

    Di Fabio, Giovanni; Romanucci, Valeria; Zarrelli, Mauro; Giordano, Michele; Zarrelli, Armando

    2013-12-04

    Gymnema sylvestre R. Br., one of the most important medicinal plants of the Asclepiadaceae family, is a herb distributed throughout the World, predominantly in tropical countries. The plant, widely used for the treatment of diabetes and as a diuretic in Indian proprietary medicines, possesses beneficial digestive, anti-inflammatory, hypoglycemic and anti-helmentic effects. Furthermore, it is believed to be useful in the treatment of dyspepsia, constipation, jaundice, hemorrhoids, cardiopathy, asthma, bronchitis and leucoderma. A literature survey revealed that some other notable pharmacological activities of the plant such as anti-obesity, hypolipidemic, antimicrobial, free radical scavenging and anti-inflammatory properties have been proven too. This paper aims to summarize the chemical and pharmacological reports on a large group of C-4 gem-dimethylated pentacyclic triterpenoids from Gymnema sylvestre.

  10. Developments of a large area VUV sensitive gas PMT with GEM/muPIC

    Energy Technology Data Exchange (ETDEWEB)

    Sekiya, H [Kamioka Observatory, Institute for Cosmic Ray Research, University of Tokyo, 456 Higashi-Mozumi, Hida, Gifu, 506-1205 (Japan); Ida, C; Kubo, H; Kurosawa, S; Tanimori, T [Department of Physics, Graduate School of Science, Kyoto University, Kitashirakawa-oiwake, Sakyo, Kyoto, 606-8502 (Japan); Yoshikawa, A; Yanagida, T; Yokota, Y [Institute of Multidisciplinary Research for Advanced Materials, Tohoku University, 2-1-1 Katahira, Aoba, Sendai, Miyagi, 980-8577 (Japan); Fukuda, K; Ishizu, S; Kawaguchi, N; Suyama, T, E-mail: sekiya@icrr.u-tokyo.ac.j [Tokuyama Corporation, 3-3-1 Shibuya, Shibuya, Tokyo, 150-8383 (Japan)

    2009-11-15

    A new large area UV photon detector with micro pattern gaseous detectors is developed and evaluated. A semitransparent CsI photocathode deposited on a MgF{sub 2} window was combined with 10cm x 10cm GEM and muPIC. Using Ar+C{sub 2}H{sub 6} (10%) gas, we achieved the gas gain of more than 10{sup 5} which is enough to detect single photoelectron. We, then, irradiated vacuum UV photons (VUV, around 172nm) from the newly developed LaF{sub 3}(Nd) scintillator to the detector and the single photoelectrons were successfully detected. We also demonstrated the imaging capability of the detector with muPIC readout systems.

  11. Conceptual design and development of GEM based detecting system for tomographic tungsten focused transport monitoring

    Science.gov (United States)

    Chernyshova, M.; Czarski, T.; Malinowski, K.; Kowalska-Strzęciwilk, E.; Poźniak, K.; Kasprowicz, G.; Zabołotny, W.; Wojeński, A.; Kolasiński, P.; Mazon, D.; Malard, P.

    2015-10-01

    Implementing tungsten as a plasma facing material in ITER and future fusion reactors will require effective monitoring of not just its level in the plasma but also its distribution. That can be successfully achieved using detectors based on Gas Electron Multiplier (GEM) technology. This work presents the conceptual design of the detecting unit for poloidal tomography to be tested at the WEST project tokamak. The current stage of the development is discussed covering aspects which include detector's spatial dimensions, gas mixtures, window materials and arrangements inside and outside the tokamak ports, details of detector's structure itself and details of the detecting module electronics. It is expected that the detecting unit under development, when implemented, will add to the safe operation of tokamak bringing the creation of sustainable nuclear fusion reactors a step closer. A shorter version of this contribution is due to be published in PoS at: 1st EPS conference on Plasma Diagnostics

  12. Analysis of data recorded by the LCTPC equipped with a two layer GEM-system

    CERN Document Server

    Ljunggren, M

    2012-01-01

    wire based readout. The prototype TPC is placed in a 1 Tesla magnet at DESY and tested using an electron beam. Analyses of data taken during two different measurement series, in 2009 and 2010, are presented here. The TPC was instrumented with a two layer GEM system and read out using modified electronics from the ALICE experiment, including the programmable charge sensitive preamp-shaper PCA16. The PCA16 chip has a number of programmable parameters which allows studies to determine the settings optimal to the final TPC. Here, the impact of the shaping time on the space resolution in the drift direction was studied. It was found that a shaping time of 60 ns is the b...

  13. A dynamic method for charging-up calculations: the case of GEM

    CERN Document Server

    Correia, P M M; Azevedo, C D R; Silva, A L M; Veenhof, R; Nemallapudi, Mythra Varun; Veloso, J F C A

    2014-01-01

    The simulation of Micro Pattern Gaseous Detectors (MPGDs) signal response is an important and powerful tool for the design and optimization of such detectors. However, several attempts to simulate exactly the effective charge gain have not been completely successful. Namely, the gain stability over time has not been fully understood. Charging-up of the insulator surfaces have been pointed as one of the responsible for the difference between experimental and Monte Carlo results. This work describes two iterative methods to simulate the charging-up in one MPGD device, the Gas Electron Multiplier (GEM). The first method uses a constant step for avalanches time evolution, very detailed, but slower to compute. The second method uses a dynamic step that improves the computing time. Good agreement between both methods was reached. Despite of comparison with experimental results shows that charging-up plays an important role in detectors operation, should not be the only responsible for the difference between simulat...

  14. Overview of large area triple-GEM detectors for the CMS forward muon upgrade

    Science.gov (United States)

    Abbaneo, D.; Abbas, M.; Abbrescia, M.; Abi Akl, M.; Aboamer, O.; Acosta, D.; Ahmad, A.; Ahmed, W.; Aleksandrov, A.; Altieri, P.; Asawatangtrakuldee, C.; Aspell, P.; Assran, Y.; Awan, I.; Bally, S.; Ban, Y.; Banerjee, S.; Barashko, V.; Barria, P.; Bencze, G.; Beni, N.; Benussi, L.; Bhopatkar, V.; Bianco, S.; Bos, J.; Bouhali, O.; Braghieri, A.; Braibant, S.; Buontempo, S.; Calabria, C.; Caponero, M.; Caputo, C.; Cassese, F.; Castaneda, A.; Cauwenbergh, S.; Cavallo, F. R.; Celik, A.; Choi, M.; Choi, S.; Christiansen, J.; Cimmino, A.; Colafranceschi, S.; Colaleo, A.; Garcia, A. Conde; Czellar, S.; Dabrowski, M. M.; De Lentdecker, G.; De Oliveira, R.; de Robertis, G.; Dildick, S.; Dorney, B.; Endroczi, G.; Errico, F.; Fenyvesi, A.; Ferry, S.; Furic, I.; Giacomelli, P.; Gilmore, J.; Golovtsov, V.; Guiducci, L.; Guilloux, F.; Gutierrez, A.; Hadjiiska, R. M.; Hauser, J.; Hoepfner, K.; Hohlmann, M.; Hoorani, H.; Iaydjiev, P.; Jeng, Y. G.; Kamon, T.; Karchin, P.; Korytov, A.; Krutelyov, S.; Kumar, A.; Kim, H.; Lee, J.; Lenzi, T.; Litov, L.; Loddo, F.; Madorsky, A.; Maerschalk, T.; Maggi, M.; Magnani, A.; Mal, P. K.; Mandal, K.; Marchioro, A.; Marinov, A.; Majumdar, N.; Merlin, J. A.; Mitselmakher, G.; Mohanty, A. K.; Mohapatra, A.; Molnar, J.; Muhammad, S.; Mukhopadhyay, S.; Naimuddin, M.; Nuzzo, S.; Oliveri, E.; Pant, L. M.; Paolucci, P.; Park, I.; Passeggio, G.; Pavlov, B.; Philipps, B.; Piccolo, D.; Postema, H.; Puig Baranac, A.; Radi, A.; Radogna, R.; Raffone, G.; Ranieri, A.; Rashevski, G.; Riccardi, C.; Rodozov, M.; Rodrigues, A.; Ropelewski, L.; RoyChowdhury, S.; Ryu, G.; Ryu, M. S.; Safonov, A.; Salva, S.; Saviano, G.; Sharma, A.; Sharma, A.; Sharma, R.; Shah, A. H.; Shopova, M.; Sturdy, J.; Sultanov, G.; Swain, S. K.; Szillasi, Z.; Talvitie, J.; Tatarinov, A.; Tuuva, T.; Tytgat, M.; Vai, I.; Stenis, M. Van; Venditti, R.; Verhagen, E.; Verwilligen, P.; Vitulo, P.; Volkov, S.; Vorobyev, A.; Wang, D.; Wang, M.; Yang, U.; Yang, Y.; Yonamine, R.; Zaganidis, N.; Zenoni, F.; Zhang, A.

    2017-02-01

    In order to cope with the harsh environment expected from the high luminosity LHC, the CMS forward muon system requires an upgrade. The two main challenges expected in this environment are an increase in the trigger rate and increased background radiation leading to a potential degradation of the particle ID performance. Additionally, upgrades to other subdetectors of CMS allow for extended coverage for particle tracking, and adding muon system coverage to this region will further enhance the performance of CMS. Following an extensive R&D program, CMS has identified triple-foil gas electron multiplier (GEM) detectors as a solution for the first muon station in the region 1.6 R&D is ongoing for additional regions.

  15. Triple-GEM detectors for the innermost region of the muon apparatus at the LHCb experiment

    CERN Document Server

    Poli-Lener, M; Bencivenni, G

    2005-01-01

    The LHCb experiment will take place at the future LHC accelerator at CERN and will start in 2007. It is a single arm spectrometer to precision measurements of CP violation and rare decays in the b quark sector. Recent experimental results have shown that CP violation is large in this sector. LHCb is designed with a robust and flexible trigger in order to extensively gain access to a wide spread of different physical processes involving the beauty particles. This will allow to over-constrain the Standard Model predictions about $\\mathcal{CP}$ violation, and to discover any possible inconsistency, which would reveal the presence of ''New Physics''. The work presented in this thesis has two main parts: the development of a charged particle detector based on Gas Electron Multiplication (GEM) and the study of luminosity measurements with the physical channels $Z^{0} \\rightarrow \\mu^{+} \\mu^{-}$ and $W^{\\pm} \\rightarrow \\mu^{\\pm} \

  16. Simulation of the time-projection chamber with triple GEMs for the LAMPS at RAON

    Science.gov (United States)

    Jhang, Genie; Lee, Jung Woo; Moon, Byul; Hong, Byungsik; Ahn, Jung Keun; Lee, Jong-Won; Lee, Kyong Sei; Kim, Young Jin; Lee, Hyo Sang

    2016-03-01

    The time-projection chamber (TPC) with triple gas-electron multipliers (GEMs) is designed for the large-acceptance multipurpose spectrometer (LAMPS) at the new radioactive ion-beam facility RAON, a pure Korean term for the accelerator complex, in Korea. The simulation environment has been set up to test the performance of the designed chamber, and the software package for analysis has been developed. Particle identification has been demonstrated to be possible up to 2 GeV/ c in momentum for particles with the charge number 1 and 2 by using the simulated heavy-ion events. The transverse-momentum resolutions are expected to be about 2% for protons and about 1.3% for pions in the relatively high-momentum region. The total reconstruction efficiencies are estimated to be about 90 and 80% for charged pions and protons, respectively.

  17. A GEM-based Time Projection Chamber for the AMADEUS experiment

    CERN Document Server

    Lener, M Poli; Corradi, G; Curceanu, C; D'Uffizi, A; Paglia, C; Sbardella, E; Scordo, A; Tagnani, D; Vidal, A Romero; Zmeskal, J

    2013-01-01

    In this paper we present the R&D activity on a new GEM-based TPC prototype for AMADEUS, a new experimental proposal at the DA{\\Phi}NE {\\Phi}-factory at the Laboratori Nazionali di Frascati (INFN), aiming to perform measurements of the low-energy negative kaons interactions in nuclei. Such innovative detector will equip the inner part of the experiment in order to perfom a better reconstruction of the primary vertex and the secondary particles tracking. A 10x10 cm2 prototype with a drift gap up to 15 cm was realized and succesfully tested at the {\\pi} M1 beam facility of the Paul Scherrer Institut (PSI) with low momentum hadrons. The measurements of the detector efficiency and spatial resolution have been performed. The results as a function of the gas gain, drift field, front-end electronic threshold and particle momentum are reported and discussed.

  18. White Paper on GEMS Study of Polarized X-rays from Neutron Stars

    CERN Document Server

    Ghosh, Pranab; Baring, Matthew; Baumgartner, Wayne; Black, Kevin; Dotson, Jessie; Harding, Alice; Hill, Joanne; Jahoda, Keith; Kaaret, Phillip; Kallman, Tim; Krawczynski, Henric; Krolik, Julian; Lai, Dong; Markwardt, Craig; Marshall, Herman; Martoff, Jeffrey; Morris, Robin; Okajima, Takashi; Petre, Robert; Poutanen, Juri; Reynolds, Stephen; Scargle, Jeffrey; Schnittman, Jeremy; Serlemitsos, Peter; Soong, Yang; Strohmayer, Tod; Swank, Jean; Tawara, Y; Tamagawa, Toru

    2013-01-01

    We examine the expected X-ray polarization properties of neutron-star X-ray sources of various types, e.g., accretion and rotation powered pulsars, magnetars, and low-mass X-ray binaries. We summarize the model calculations leading to these expected properties. We describe how a comparison of these with their observed properties, as inferred from GEMS data, will probe the essential dynamical, electromagnetic, plasma, and emission processes in neutron-star binaries, discriminate between models of these processes, and constrain model parameters. An exciting goal is the first observational demonstration in this context of the existence of vacuum resonance, a fundamental quantum electrodynamical phenomenon first described in the 1930s.

  19. White Paper for Blazar Observations with a GEMS-like X-ray Polarimetry Mission

    CERN Document Server

    Krawczynski, Henric; Baring, Matthew; Baumgartner, Wayne; Black, Kevin; Dotson, Jessie; Ghosh, Pranab; Harding, Alice; Hill, Joanne; Jahoda, Keith; Kaaret, Phillip; Kallman, Tim; Krolik, Julian; Lai, Dong; Markwardt, Craig; Marshall, Herman; Martoff, Jeffrey; Morris, Robin; Okajima, Takashi; Petre, Robert; Poutanen, Juri; Reynolds, Stephen; Scargle, Jeffrey; Schnittman, Jeremy; Serlemitsos, Peter; Soong, Yang; Strohmayer, Tod; Swank, Jean; Tawara, Yuzuru; Tamagawa, Toru

    2013-01-01

    In this document, we describe the scientific potential of blazar observations with a X-ray polarimetry mission like GEMS (Gravity and Extreme Magnetism SMEX). We describe five blazar science investigations that such a mission would enable: (i) the structure and the role of magnetic fields in AGN jets, (ii) analysis of the polarization of the synchrotron X-ray emission from AGN jets, (iii) discrimination between synchrotron self-Compton and external Compton models for blazars with inverse Compton emission in the X-ray band, (iv) a precision study of the polarization properties of the X-ray emission from Cen-A, (v) tests of Lorentz Invariance based on X-ray polarimetric observations of blazars. We conclude with a discussion of a straw man observation program and recommended accompanying multiwavelength observations.

  20. X-ray Polarization from Black Holes: GEMS Scientific White Paper

    CERN Document Server

    Schnittman, Jeremy; Baring, Matthew; Baumgartner, Wayne; Black, Kevin; Dotson, Jessie; Ghosh, Pranab; Harding, Alice; Hill, Joanne; Jahoda, Keith; Kaaret, Phillip; Kallman, Tim; Krawczynski, Henric; Krolik, Julian; Lai, Dong; Markwardt, Craig; Marshall, Herman; Martoff, Jeffrey; Morris, Robin; Okajima, Takashi; Petre, Robert; Poutanen, Juri; Reynolds, Stephen; Scargle, Jeffrey; Serlemitsos, Peter; Soong, Yang; Strohmayer, Tod; Swank, Jean; Tawara, Yuzuru; Tamagawa, Toru

    2013-01-01

    We present here a summary of the scientific goals behind the Gravity and Extreme Magnetism SMEX (GEMS) X-ray polarimetry mission's black hole (BH) observing program. The primary targets can be divided into two classes: stellar-mass galactic BHs in accreting binaries, and super-massive BHs in the centers of active galactic nuclei (AGN). The stellar-mass BHs can in turn be divided into various X-ray spectral states: thermal-dominant (disk), hard (radio jet), and steep power-law (hot corona). These different spectral states are thought to be generated by different accretion geometries and emission mechanisms. X-ray polarization is an ideal tool for probing the geometry around these BHs and revealing the specific properties of the accreting gas.

  1. 3D field calculation of the GEM prototype magnet and comparison with measurements

    Energy Technology Data Exchange (ETDEWEB)

    Lari, R.J.

    1983-10-28

    The proposed 4 GeV Electron Microtron (GEM) is designed to fill the existing buildings left vacant by the demise of the Zero Gradient Synchrotron (ZGS) accelerator. One of the six large dipole magnets is shown as well as the first 10 electron orbits. A 3-orbit prototype magnet has been built. The stepped edge of the magnet is to keep the beam exiting perpendicular to the pole. The end guards that wrap around the main coils are joined together by the 3 shield plates. The auxiliary coils are needed to keep the end guards and shield plates from saturating. A 0.3 cm Purcell filter air gap exists between the pole and the yoke. Can anyone question this being a truly three-dimensional magnetostatic problem. The computer program TOSCA, developed at the Rutherford Appleton Laboratory by the Computing Applications Group, was used to calculate this magnet and the results have been compared with measurements.

  2. Fiber Bragg Grating sensors for deformation monitoring of GEM foils in HEP detectors

    CERN Document Server

    AUTHOR|(CDS)2071648; Bianco, S; Caponero, M; Muhammad, S; Passamonti, L; Piccolo, D; Pierluigi, D; Raffone, G; Russo, A; Saviano, G

    2015-01-01

    Fiber Bragg Grating (FBG) sensors have been so far mainly used in high energy physics (HEP) as high precision positioning and re-positioning sensors and as low cost, easy to mount, radiation hard and low space- consuming temperature and humidity devices. FBGs are also commonly used for very precise strain measurements. In this work we present a novel use of FBGs as flatness and mechanical tensioning sensors applied to the wide Gas Electron Multiplier (GEM) foils of the GE1/1 chambers of the Compact Muon Solenoid (CMS) experiment at Large Hadron Collider (LHC) of CERN. A network of FBG sensors has been used to determine the optimal mechanical tension applied and to characterize the mechanical stress applied to the foils. The preliminary results of the test performed on a full size GE1/1 final prototype and possible future developments will be discussed.

  3. Dst Index in the 2008 GEM Modeling Challenge - Model Performance for Moderate and Strong Magnetic Storms

    Science.gov (United States)

    Rastaetter, Lutz; Kuznetsova, Maria; Hesse, Michael; Chulaki, Anna; Pulkkinen, Antti; Ridley, Aaron J.; Gombosi, Tamas; Vapirev, Alexander; Raeder, Joachim; Wiltberger, Michael James; Mays, M. L.; Fok, Mei-Ching H.; Weigel, Robert S.; Welling, Daniel T.

    2010-01-01

    The GEM 2008 modeling challenge efforts are expanding beyond comparing in-situ measurements in the magnetosphere and ionosphere to include the computation of indices to be compared. The Dst index measures the largest deviations of the horizontal magnetic field at 4 equatorial magnetometers from the quiet-time background field and is commonly used to track the strength of the magnetic disturbance of the magnetosphere during storms. Models can calculate a proxy Dst index in various ways, including using the Dessler-Parker Sckopke relation and the energy of the ring current and Biot-Savart integration of electric currents in the magnetosphere. The GEM modeling challenge investigates 4 space weather events and we compare models available at CCMC against each other and the observed values of Ost. Models used include SWMF/BATSRUS, OpenGGCM, LFM, GUMICS (3D magnetosphere MHD models), Fok-RC, CRCM, RAM-SCB (kinetic drift models of the ring current), WINDMI (magnetosphere-ionosphere electric circuit model), and predictions based on an impulse response function (IRF) model and analytic coupling functions with inputs of solar wind data. In addition to the analysis of model-observation comparisons we look at the way Dst is computed in global magnetosphere models. The default value of Dst computed by the SWMF model is for Bz the Earth's center. In addition to this, we present results obtained at different locations on the Earth's surface. We choose equatorial locations at local noon, dusk (18:00 hours), midnight and dawn (6:00 hours). The different virtual observatory locations reveal the variation around the earth-centered Dst value resulting from the distribution of electric currents in the magnetosphere during different phases of a storm.

  4. Application of model output statistics to the GEM-AQ high resolution air quality forecast

    Science.gov (United States)

    Struzewska, J.; Kaminski, J. W.; Jefimow, M.

    2016-11-01

    The aim of the presented work was to analyse the impact of data stratification on the efficiency of the Model Output Statistics (MOS) methodology as applied to a high-resolution deterministic air quality forecast carried out with the GEM-AQ model. The following parameters forecasted by the GEM-AQ model were selected as predictors for the MOS equation: pollutant concentration, air temperature in the lowest model layer, wind speed in the lowest model layer, temperature inversion and the precipitation rate. A representative 2-year series were used to construct regression functions. Data series were divided into two subsets. Approximately 75% of the data (first 3 weeks of each month) were used to estimate the regression function parameters. Remaining 25% (last week of each month) were used to test the method (control period). The subsequent 12 months were used for method verification (verification period). A linear model fitted the function based on forecasted parameters to the observations. We have assumed four different temperature-based data stratification methods (for each method, separate equations were constructed). For PM10 and PM2.5, SO2 and NO2 the best correction results were obtained with the application of temperature thresholds in the cold season and seasonal distribution combined with temperature thresholds in the warm season. For the PM10, PM2.5 and SO2 the best results were obtained using a combination of two stratification methods separately for cold and warm seasons. For CO, the systematic bias of the forecasted concentrations was partly corrected. For ozone more sophisticated methods of data stratification did not bring a significant improvement.

  5. Synthesis and Electronic Structure of Ru2(Xap)4(Y-gem-DEE) Type Compounds: Effect of Cross-Conjugation.

    Science.gov (United States)

    Forrest, William P; Choudhuri, Mohommad M R; Kilyanek, Stefan M; Natoli, Sean N; Prentice, Boone M; Fanwick, Phillip E; Crutchley, Robert J; Ren, Tong

    2015-08-03

    Reported in this Article are the preparation and characterization of a series of new Ru2(II,III) compounds bearing one cross-conjugated σ-geminal-diethynylethene ligand (gem-DEE), namely, Ru2(Xap)4(Y-gem-DEE) (Xap = N,N'-anilinopyridinate (ap) or 2-(3,5-dimethoxy)anilinopyridinate (DiMeOap), and Y = Si(i)Pr3 (1) or H (2)) and [Ru2(ap)4]2(μ-gem-DEE) (3). Compounds 1-3 were characterized by spectroscopic and voltammetric techniques as well as the single crystal X-ray diffraction study of 2a. The X-ray structural data of 2a and the spectroscopic/voltammetric data of compounds 1 and 2 indicate that the gem-DEE ligands are similar to simple alkynyls in their effects on the molecular and electronic structures of the Ru2(Xap)4 moiety. Similar to the previously studied [Ru2(ap)4]2(μ-C2n) type compounds, dimer 3 exhibits pairwise 1e(-) oxidations and reductions, albeit the potential splits within the pair (ΔE1/2) are significantly smaller than those of [Ru2(ap)4]2(μ-C4). The electronic absorption spectra of the reduced and oxidized derivatives of 1a and 3 were determined using spectroelectrochemistry methods. No discernible intervalence charge transfer transition (IVCT) was detected in the near-IR spectrum for either 3(-) or 3(+), suggesting that the Ru2-Ru2 coupling in these mixed-valence states is weak. DFT calculations on a model compound of 3 yielded six singly occupied molecular orbitals (SOMOs), which have Ru2 contributions similar to those previously calculated for the [Ru2(ap)4]2(μ-C2n) type compounds. Among six SOMOs, SOMO-2 is the only one containing substantial dπ-π(gem-DEE) character across the entire Ru2-μ-gem-DEE-Ru2 linkage, which explains the weakened Ru2-Ru2 coupling.

  6. GEM 3000与雅培I-STAT血气分析仪结果比对分析%Comparison analysis of GEM 3000 and Abbott I-STAT blood gas analyzers

    Institute of Scientific and Technical Information of China (English)

    谌海兰; 陈特; 徐华建; 毕小云

    2016-01-01

    目的:确保相同标本在不同的血气分析仪上的检测结果具有可比性,对医院使用GEM Premier3000血气分析仪(简称GEM 3000)与雅培I-STAT血气分析仪(简称雅培I-STAT)进行比较,保证使用于临床的血气分析仪能正确反映病人的血气情况。方法22台血气分析仪,其中雅培I-STAT 11台,GEM 300011台。采用相同的血气质控物对两款血气分析仪进行检测,以美国CLIA’88为标准对参加比对的仪器进行评价,并与检验科参加过全国卫生和计划生育委员会室间质评的血气分析仪进行比对,计算两种型号血气分析仪之间的偏倚。结果发现胸心外科1台GEM 3000的氧分压在2号和3号标本中检测结果偏高(分别是113 mmHg、172 mmHg),超过了允许的最大范围,比对不符合要求。对不符合比对要求的血气分析仪进行校准并再次比对,合格后给予临床使用。结论临床检测中尽量使用相同型号的血气分析仪,若型号不同,应定期进行比对,保证结果具有可比性。%Objective To compare 2 kinds of blood gas analyzers GEM Premier3000(GEM3000) and Abbott I-STAT for test-ing comparability of results with same samples, and ensure analyzers qualified eventually for blood gas analysis in clinic. Methods Two kinds of 22 blood gas analyzers were enrolled, which included 11 Abbott I-STAT and 11 GEM 3000. The two kinds of blood gas analyzers were tested with same blood quality control material and evaluated by standard of American CLI-A’88. Then compared with blood gas analyzer which was approved by external quality assessment of department of clinical laboratories by National Health and Family Planning Commission, and the bias of 2 kinds of blood gas analyzers were calcu-lated. Results The PO2 test results of No.2(113 mmHg) and No.3(172 mmHg) samples from GEM 3000 analyzer at Department of Cardiothoracic Surgery were higher than maximum range and imcompatible. The

  7. Abdichtung von fließfettgeschmierten Getrieben mit Radialwellendichtungen - Reibungsminderung durch Makrostrukturierung der Dichtungsgegenlauffläche

    OpenAIRE

    2014-01-01

    Diese Arbeit befasst sich mit Radialwellendichtungen von fließfettgeschmierten Getrieben und den Einflüssen der einzelnen Komponenten des Dichtsystems auf dessen Funktion und Verschleiß. Verglichen mit ölgeschmierten Systemen ist der Schmierstoffaustausch in fließfettgeschmierten Getrieben deutlich geringer. Hohe Dichtsystemtemperaturen bis hin zu globaler Mangelschmierung sind die Folgen. Anhand eines praxisnahen Experimentalgetriebes mit einem Wellendurchmesser von 50mm erfolgt eine systema...

  8. Kasuistik 2: 54-jähriger LKW-Fernfahrer mit Verdacht auf Schilddrüsenunterfunktion

    Directory of Open Access Journals (Sweden)

    Jockenhövel F

    2003-01-01

    Full Text Available 54-jähriger LKW-Fernfahrer mit Leistungsschwäche, Rückenschmerzen, erektiler Dysfunktion, vermehrter Müdigkeit. Wird vom Hausarzt mit der Frage einer eventuellen Schilddrüsenunterfunktion (Hypothyreose vorgestellt. Keine relevanten Vorerkrankungen, gelegentlich Voltaren als Medikation gegen Rückenschmerzen. Auf Befragen erektile Dysfunktion mit mangelnder Rigidität zur Emission, bzw. zu schnellem Verlust der Rigidität.

  9. “Die Lexik mit dem semantischen Merkmal ‚Emotionalität’ der deutschen und der makedonischen Gegenwartssprache“

    OpenAIRE

    Ivanovska, Biljana

    2005-01-01

    Im Mittelpunkt dieses Beitrags steht die Zusammenfassung der Doktorarbeit: “Die Lexik mit dem semantischen Merkmal ‚Emotionalität’ der deutschen und der makedonischen Gegenwartssprache“ und die Untersuchung der emotional wertenden Lexik beider Sprachsysteme mit einem kontrastiven Sprachvergleich. “Die Lexik mit dem semantischen Merkmal ‚Emotionalität’ der deutschen und der makedonischen Gegewartssprache“ wird als Doktorarbeit an der Philologischen Fakultät „Blaze Koneski“ in Skopje verteidigt...

  10. Behandlung psychotischer Störungen - Aspekte der Therapiebeziehung und Untersuchung unmedizierter Menschen mit psychotischen Störungen

    OpenAIRE

    2015-01-01

    Die vorliegende kumulative Dissertation befasst sich mit der Behandlung psychotischer Störungen und setzt sich aus drei Studien zusammen. Dabei werden mit dem Fokus auf Therapieprozesse im Rahmen der Kognitiven Verhaltenstherapie für Psychosen (Studien 1 und 2) sowie auf die spezifische Gruppe der unmedizierten Personen mit psychotischen Störungen (Studie 3) zwei inhaltliche Schwerpunkte gesetzt. Die therapeutische Beziehung in de...

  11. Design, synthesis and in vivo anti-hyperglycemic activity of gem-dimethyl-bearing C-glucosides as SGLT2 inhibitors

    Institute of Scientific and Technical Information of China (English)

    Wen Jing Zhao; Yong Heng Shi; Gui Long Zhao; Yu Li Wang; Hua Shao; Li Da Tang; Jian Wu Wang

    2011-01-01

    A series of gem-dimethyl-bearing C-glucosides were designed and synthesized as SGLT2 inhibitors, with anhydrous aluminum chloride-mediated Friedel-Crafts alkylation to construct the gem-dimethyl functionality being the key step. The in vivo anti-hyperglycemic activity was evaluated with mice oral glucose tolerance test (OGTT), and all the synthesized compounds showed significant but less potent anti-hyperglycemic activity than the positive control dapagliflozin.

  12. Summary of FY 1997 related to JAPC-U.S. DOE contract study on improvement of core safety -- study on GEM (III)

    Energy Technology Data Exchange (ETDEWEB)

    Burke, T.M.

    1998-02-03

    FFTF was originally designed/constructed/operated to develop LMFBR fuels and materials. Inherent safety became a major focus of the US nuclear industry in the mid 1980`s. The inherent safety characteristics of LMFBRs were recognized but additional enhancement was desired. The presentation contents are: Fast Flux Test Facility history and status; Overview of contract activities; Summary of loss of flow without scram with GEMs testing; and Summary of pump start with GEMs testing.

  13. Mit1 Transcription Factor Mediates Methanol Signaling and Regulates the Alcohol Oxidase 1 (AOX1) Promoter in Pichia pastoris.

    Science.gov (United States)

    Wang, Xiaolong; Wang, Qi; Wang, Jinjia; Bai, Peng; Shi, Lei; Shen, Wei; Zhou, Mian; Zhou, Xiangshan; Zhang, Yuanxing; Cai, Menghao

    2016-03-18

    The alcohol oxidase 1 (AOX1) promoter (P AOX1) of Pichia pastoris is the most powerful and commonly used promoter for driving protein expression. However, mechanisms regulating its transcriptional activity are unclear. Here, we identified a Zn(II)2Cys6-type methanol-induced transcription factor 1 (Mit1) and elucidated its roles in regulating PAOX1 activity in response to glycerol and methanol. Mit1 regulated the expression of many genes involved in methanol utilization pathway, including AOX1, but did not participate in peroxisome proliferation and transportation of peroxisomal proteins during methanol metabolism. Structural analysis of Mit1 by performing domain deletions confirmed its specific and critical role in the strict repression of P AOX1 in glycerol medium. Importantly, Mit1, Mxr1, and Prm1, which positively regulated P AOX1 in response to methanol, were bound to P AOX1 at different sites and did not interact with each other. However, these factors cooperatively activated P AOX1 through a cascade. Mxr1 mainly functioned during carbon derepression, whereas Mit1 and Prm1 functioned during methanol induction, with Prm1 transmitting methanol signal to Mit1 by binding to the MIT1 promoter (P MIT1), thus increasingly expressing Mit1 and subsequently activating P AOX1.

  14. Charakterisierung und Optimierung der Grenzflächenstabilisierung von Wasser-in-Öl-Emulsionen mit Ethylcellulose als Polymeremulgator

    OpenAIRE

    Maurath, Stephan

    2007-01-01

    Die (Lager-)Stabilität ausschließlich mit Ethylcellulose (EC) stabilisierter, gießfähiger W/O-Emulsionen mit Octyldodecanol als Ölphase ist für eine praktische Anwendung nicht ausreichend. Ziel der vorliegenden Arbeit ist – aufbauend auf eine systematische Charakterisierung – eine Optimierung der Grenzflächenstabilisierung ausschließlich mit Ethylcellulose stabilisierter, gießfähiger W/O-Emulsionen. Mit Hilfe von Messungen der dynamischen Grenzflächenspannungen und Grenzflächen-rheologie (...

  15. Designs of LiMIT as a Limiter in the EAST Tokamak

    Science.gov (United States)

    Szott, Matthew; Christenson, Michael; Kalathiparambil, Kishor; Ruzic, David

    2016-10-01

    Liquid metal plasma facing components (PFCs) provide a constantly refreshing, self-healing surface that can reduce erosion and thermal stress damage to prolong device lifetime, and additionally decrease edge recycling, reduce impurities, and enhance plasma performance. The Liquid Metal Infused Trench (LiMIT) system, developed at UIUC, has demonstrated thermoelectric magnetohydrodynamic (TEMHD) driven flow of liquid lithium through series of solid trenches. This TEMHD effect drives liquid lithium in fusion systems using the plasma heat flux and the toroidal magnetic field, and the surface tension of the liquid lithium maintains a fresh surface on top of the solid trenches. LiMIT has been successfully tested at UIUC as well as HT-7 and Magnum PSI at heat fluxes up to 3 MW/m2. The next step is demonstrating system viability in full-scale fusion-relevant conditions. In collaboration with a team in Hefei, design and testing has begun for a large scale LiMIT system that will act as a limiter in EAST. The designs improve upon previous versions of LiMIT tested at Illinois and incorporate lessons learned from earlier tests of liquid metal PFCs at EAST. Existing infrastructure is used to load and supply lithium to the system, and the LiMIT trenches will help maintain a smooth, fresh surface as well as aid in propelling the lithium out of direct plasma flux to improve heat transfer. Supported by DOE/ALPS DE-FG02-99ER54515.

  16. Die "Single-Shot-Therapie" für Patientinnen mit unkompliziertem Harnwegsinfekt

    Directory of Open Access Journals (Sweden)

    Hanzal E

    1999-01-01

    Full Text Available Der Harntrakt ist bei der Frau aus anatomischen und hormonellen Gründen einer der häufigsten Angriffspunkte bakterieller Infektionen. Als Risikofaktoren gelten Kohabitationen, die Verwendung bestimmter Kontrazeptiva (spermizide Creme und/oder Scheidendiaphragma und vorangegangene Zystitiden. Unkomplizierte Harnwegsinfekte sind mittels gezielter Anamnese, klinischer Untersuchung und Streifentest im Rahmen einer abgekürzten Diagnostik leicht festzustellen. Der Verzicht auf eine antibiotische Therapie ist aufgrund der möglichen gefährlichen Folgen (Pyelonephritis, Urosepsis, Nierenversagen medizinisch nicht vertretbar. Erfahrungsgemäß ist allerdings die Patientencompliance ein Problem, die neben der Gefahr der Reinfektion auch die Möglichkeit der Resistenzentwicklung birgt. Der Trend in der Therapie der unkomplizierten Harnwegsinfektion geht daher zur Kurzzeitbehandlung (3 Tage mit potenten bakteriziden Substanzen. Mit der Zulassung von Fosfomycin-Tromethamol (Monuril® steht darüberhinaus neuerdings ein Präparat zur Verfügung, das mit einer oralen Einmaldosis eine hohe Wirksamkeit bietet, die sich mit der mehrtägigen Gabe anderer Substanzen auch im Nebenwirkungsprofil vergleichen läßt. Aus gynäkologischer Sicht ist außerdem beachtenswert, daß Fosfomycin-Tromethamol auch beim Harnwegsinfekt in der Schwangerschaft eingesetzt werden kann. Die Single-Shot Therapie mit Fosfomycin-Tromethamol (Monuril® kann somit als wirksame und sichere Behandlungsmethode des akuten unkomplizierten Harnwegsinfektes gelten.

  17. Correction of distortion for optimal image stacking in Wide Field Adaptive Optics: Application to GeMS data

    CERN Document Server

    Bernard, A; Neichel, B; Fusco, T; Bounissou, S; Samal, M; Andersen, M; Zavagno, A; Plana, H

    2016-01-01

    The advent of Wide Field Adaptive Optics (WFAO) systems marks the beginning of a new era in high spatial resolution imaging. The newly commissioned Gemini South Multi-Conjugate Adaptive Optics System (GeMS) combined with the infrared camera Gemini South Adaptive Optics Imager (GSAOI), delivers quasi diffraction-limited images over a field of 2 arc-minutes across. However, despite this excellent performance, some variable residues still limit the quality of the analyses. In particular, distortions severely affect GSAOI and become a critical issue for high-precision astrometry and photometry. In this paper, we investigate an optimal way to correct for the distortion following an inverse problem approach. Formalism as well as applications on GeMS data are presented.

  18. A phenomenological model to study the energy discrimination potential of GEM detectors in the X-ray range

    Energy Technology Data Exchange (ETDEWEB)

    Causa, F., E-mail: federica.causa@enea.it; Pacella, D.; Romano, A.; Claps, G.; Gabellieri, L.

    2015-11-01

    An empirical model is presented to study the operational characteristics of GEM detectors in the X-ray range and, in particular, its energy discrimination potential. Physical processes are modelled from a macroscopic point of view, to provide a simple but effective simulation tool. Experimental data from monochromatic and combined, two-line fluorescence sources, are used to validate the model and provide realistic estimates of the empirical parameters used in the description. The model is instrumental in understanding the role of threshold, gain and operational conditions to achieve energy-discriminating response. Appropriate choices of gas mixtures, threshold and gain will permit to best utilise this new functionality of the GEM to improve the efficiency of image detectors in applications ranging from in-situ imaging in harsh environments, such as tokamaks, to composite materials analysis and medical imaging of tissues.

  19. Investigating Active Accretion, Flare Activity and a 50 Million Degree Corona in the cool AGB Star, Y Gem

    Science.gov (United States)

    Sahai, Raghvendra

    2014-09-01

    We propose to make multi-epoch observations of the X-ray (and radio contiuum) emission from a cool AGB star, Y Gem. This star shows relatively strong X-ray emission implying the presence of 50 million degree coronal gas, and highly-variable FUV and NUV fluxes - likely evidence of variable accretion onto a magnetized accretion disk in a binary system. Y Gem is the most prominent member of a new class of AGB stars with FUV excesses identified using the GALEX archive. Our study will allow us to study the never-before explored phase of an active accretion disk in an AGB star with a binary companion. Such disks are believed to ultimately produce collimated jets that transform AGB circumsetllar envelopes into bipolar planetary nebulae.

  20. High granularity tracker based on a Triple-GEM optically read by a CMOS-based camera

    CERN Document Server

    Marafini, Michela; Pinci, Davide; Sarti, Alessio; Sciubba, A; Spiriti, Eleuterio

    2015-01-01

    The detection of photons produced during the avalanche development in gas chambers has been well studied in the past. The great progresses achieved in last years in the performance of micro-pattern gas detectors on one side and of photo-sensors on the other provide the possibility of making high granularity and very sensitive particle trackers. In this paper, the results obtained with a triple-GEM structure read-out by a CMOS based sensor are described. The use of an He/CF$_4$ (60/40) gas mixture and a suitable study of the electric fields made possible to optimise GEM light yield. About 100 photons per primary electron were detected by the sensor resulting in a very good capability of tracking muons from cosmic rays.

  1. GEM:A Mission Concept for Monitoring Point Sources Emissions of CO2 and CH4 from Space

    Science.gov (United States)

    Prunet, P.; Jeansou, E.; Camy-Peyret, C.; Ernst, R.; Tesmer, V.; Bordeleau, M.; Payen, L.; Lecuyot, A.

    2016-08-01

    GEM (Gas Emission Mission) is a carbon dioxide and methane point source detection concept analysed in the context of ESA's "Space and Energy" initiative [1]. Starting from a consultation of user needs from the Energy Sectors, mission objectives have been derived for the detection and quantification of surface fluxes at local scales. A new EO concept has been proposed: GEM, a GHG mission based on a SWIR spectro-imager to measure anthropogenic emissions of CO2 and CH4 for GHG emission inventory and leaks detection and with a SWIR optical sensor. A preliminary study of the system including instruments, platform, launch, ground segment, programmatics, costs and feasibility assessment was performed, as well as a cost/benefit analysis.

  2. Correction of distortion for optimal image stacking in wide field adaptive optics: application to GeMS data

    Science.gov (United States)

    Bernard, Anaïs.; Mugnier, Laurent M.; Neichel, Benoit; Fusco, Thierry; Bounissou, Sophie; Samal, Manash; Andersen, Morten; Zavagno, Annie; Plana, Henri

    2016-07-01

    The advent of Wide Field Adaptive Optics (WFAO) systems marks the beginning of a new era in high spatial resolution imaging. The newly commissioned Gemini South Multi-Conjugate Adaptive Optics System (GeMS) combined with the infrared camera Gemini South Adaptive Optics Imager (GSAOI), delivers quasi diffraction-limited images over a field of 2 arc-minutes across. However, despite this excellent performance, some variable residues still limit the quality of the analyses. In particular, distortions severely affect GSAOI and become a critical issue for high-precision astrometry and photometry. In this paper, we investigate an optimal way to correct for the distortion following an inverse problem approach. Formalism as well as applications on GeMS data are presented.

  3. Low Cost DNA Molecular Weight Marker: Primer-Directed Synthesis from pGEM-T Easy Vector

    Directory of Open Access Journals (Sweden)

    Siriporn RIYAJAN

    2011-06-01

    Full Text Available A low cost DNA molecular weight marker was produced by a marker primer-directed synthetic method using pGEM-T Easy vector as the DNA template. Seven primers were used to amplify eight different DNA fragments, which were 150, 300, 375, 500, 700, 1,000, 1,200 and 1,625 bp, from bacterial culture containing pGEM-T Easy vector. Polymerase chain reactions (PCR for all marker loci required the same optimal annealing temperature, which allowed all the PCR to be completed in a single run. To obtain the molecular weight marker, the PCR product of each locus was mixed together and directly used as marker without any further purification. This custom made molecular weight marker was found to be approximately 17 to 49 times less expensive than other commercial 100 bp DNA ladder markers.Graphical abstract

  4. SECS/GEM标准模型分析及应用%Research of SECS/GEM standard model and application

    Institute of Scientific and Technical Information of China (English)

    张鹏程; 张红雨; 陈杨

    2011-01-01

    SECS/GEM是半导体自动化生产中广泛采用的一个行业标准。首先介绍了SECS/GEM标准的整体框架,并分析了其行业发展状况,然后依次说明了SECSⅠ/Ⅱ、GEM、HSMS各个分层标准的数据报文格式、传输控制模型、状态转换模型以及相互间的通信控制方式等,最后分析了该标准在我国半导体自动化生产中的应用状况。实践表明,SECS/GEM标准设计严谨,适应面广,在我国半导体工业中应用前景广阔。%The SECS/GEM is an industry standard which is widely used in the automation of semiconductor.In this paper,the overall standard frame of SECS/GEM is introduced,and its industry development is analyzed.After that,SECSⅠ/Ⅱ,GEM and HSMS's stratification standard's data message format,transmission control model,the state transition model and mutual communication control mode are illustrated.Finally,the standard's application in our semiconductor's automatic production is analyzed.The practice shows that the SECS/GEM standard with a perfect design has a wide application prospect in homeland's semiconductor industy.

  5. Study on the Development of Industry of Internet of Things Based on Competitive GEM Model in Fujian Province

    Directory of Open Access Journals (Sweden)

    Di Jun An

    2016-01-01

    Full Text Available Firstly, the basic theories of internet of things, competitive GEM model and industrial development in Fujian Province were studied in this paper. Then, the factors influencing the cultivation of industrial competitiveness of the internet of things was observed and finally the suggestions on enhancing the competitiveness of internet of things and strengthening the cultivation of talents of internet of things were put forward.

  6. Alpha-substituted organic peroxides: synthetic strategies for a biologically important class of gem-dihydroperoxide and perketal derivatives.

    Science.gov (United States)

    Zmitek, Katja; Zupan, Marko; Iskra, Jernej

    2007-12-21

    In this paper we review the recent developments in the synthesis of alpha-substituted hydroperoxides. Alpha-substituted hydroperoxides are interesting compounds due to their chemistry and bioactivity and as intermediates for the synthesis of other peroxides, of which cyclic peroxides are of major importance. Although the emphasis of this report will be on the derivatives of gem-dihydroperoxides, perketals, as well as the less studied nitrogen and sulfur derivatives, will also be covered.

  7. The Australian bushfires of February 2009: MIPAS observations and GEM-AQ model results

    Directory of Open Access Journals (Sweden)

    N. Glatthor

    2013-02-01

    Full Text Available Starting on 7 February 2009, southeast Australia was devastated by large bushfires, which burned an area of about 3000 km2 on this day alone. This event was extraordinary, because a large number of combustion products were transported into the uppermost troposphere and lower stratosphere within a few days. Various biomass burning products released by the fire were observed by the Michelson Interferometer for Passive Atmospheric Sounding (MIPAS on the Envisat satellite. We tracked the plume using MIPAS C2H2, HCN and HCOOH single-scan measurements on a day-to-day basis. The measurements were compared with a high-resolution model run of the Global Environmental Multiscale Air Quality (GEM-AQ model. Generally there is good agreement between the spatial distribution of measured and modelled pollutants. Both MIPAS and GEM-AQ show a fast southeastward transport of the pollutants to New Zealand within one day. During the following 3–4 days, the plume remained northeastward of New Zealand and was located at altitudes of 15 to 18 km. Thereafter its lower part was transported eastward, followed by westward transport of its upper part. On 17 February the eastern part had reached southern South America and on 20 February the central South Atlantic. On the latter day a second relic of the plume was observed moving eastward above the South Pacific. Between 20 February and the first week of March, the upper part of the plume was transported westward over Australia and the Indian Ocean towards southern Africa. First evidence for entry of the pollutants into the stratosphere was found in MIPAS data of 11 February, followed by larger amounts on 17 February and the days thereafter. From MIPAS data, C2H2/HCN and HCOOH/HCN enhancement ratios of 0.76 and 2.16 were calculated for the first days after the outbreak of the fires, which are considerably higher than the emission ratios assumed for the model run and at

  8. Impact of urban parameterization on high resolution air quality forecast with the GEM – AQ model

    Directory of Open Access Journals (Sweden)

    J. W. Kaminski

    2012-04-01

    Full Text Available The aim of this study is to assess the impact of urban cover on high-resolution air quality forecast simulations with the GEM-AQ model. The impact of urban area on the ambient atmosphere is non-stationary and short-term variability of meteorological conditions may result in significant changes of the observed intensity of urban heat island and pollutant concentrations. In this study we used the Town Energy Balance (TEB parameterization to represent urban effects on modelled meteorological and air quality parameters at the final nesting level with horizontal resolution of ~5 km over Southern Poland. Three one-day cases representing different meteorological conditions were selected and the model was run with and without the TEB parameterization. Three urban cover categories were used in the TEB parameterization: mid-high buildings, sparse buildings and a mix of buildings and nature. Urban cover layers were constructed based on an area fraction of towns in a grid cell. To analyze the impact of urban parameterization on modelled meteorological and air quality parameters, anomalies in the lowest model layer for the temperature, wind speed and pollutant concentrations were calculated. Anomalies of the specific humidity fields indicate that the use of the TEB parameterization leads to a systematic reduction of moisture content in the air. Comparison with temperature and wind speed measurements taken at urban background monitoring stations shows that application of urban parameterization improves model results. For primary pollutants the impact of urban areas is most significant in regions characterized with high emissions. In most cases the anomalies of NO2 and CO concentrations are negative. This reduction is most likely caused by an enhanced vertical mixing due to elevated surface temperature and modified vertical stability. Although the outcome from this study is promising, it does not give an answer concerning the benefits of using TEB in the GEM

  9. Dynamic nature of cleavage bodies and their spatial relationship to DDX1 bodies, Cajal bodies, and gems.

    Science.gov (United States)

    Li, Lei; Roy, Ken; Katyal, Sachin; Sun, Xuejun; Bléoo, Stacey; Godbout, Roseline

    2006-03-01

    DDX1 bodies, cleavage bodies, Cajal bodies (CBs), and gems are nuclear suborganelles that contain factors involved in RNA transcription and/or processing. Although all four nuclear bodies can exist as distinct entities, they often colocalize or overlap with each other. To better understand the relationship between these four nuclear bodies, we examined their spatial distribution as a function of the cell cycle. Here, we report that whereas DDX1 bodies, CBs and gems are present throughout interphase, CPSF-100-containing cleavage bodies are predominantly found during S and G2 phases, whereas CstF-64-containing cleavage bodies are primarily observed during S phase. All four nuclear bodies associate with each other during S phase, with cleavage bodies colocalizing with DDX1 bodies, and cleavage bodies/DDX1 bodies residing adjacent to gems and CBs. Although inhibitors of RNA transcription had no effect on DDX1 bodies or cleavage bodies, inhibitors of DNA replication resulted in loss of CstF-64-containing cleavage bodies. A striking effect on nuclear structures was observed with latrunculin B, an inhibitor of actin polymerization, resulting in the formation of needlelike nuclear spicules made up of CstF-64, CPSF-100, RNA, and RNA polymerase II. Our results suggest that cleavage body components are highly dynamic in nature.

  10. Towards an automatic system for monitoring of CN2 and wind speed profiles with GeMS

    CERN Document Server

    Masciadri, E; Guesalaga, A; Turchi, A

    2016-01-01

    Wide Field Adaptive Optics (WFAO) systems represent the more sophisticated AO systems available today at large telescopes. A critical aspect for these WFAO systems in order to deliver an optimised performance is the knowledge of the vertical spatiotemporal distribution of the CN2 and the wind speed. Previous studies (Cortes et al., 2012) already proved the ability of GeMS (the Gemini Multi-Conjugated AO system) in retrieving CN2 and wind vertical stratification using the telemetry data. To assess the reliability of the GeMS wind speed estimates a preliminary study (Neichel et al., 2014) compared wind speed retrieved from GeMS with that obtained with the atmospherical model Meso-Nh on a small sample of nights providing promising results. The latter technique is very reliable for the wind speed vertical stratification. The model outputs gave, indeed, an excellent agreement with a large sample of radiosoundings (~ 50) both in statistical terms and on individual flights (Masciadri et al., 2013). Such a tool can t...

  11. Dynamic Nature of Cleavage Bodies and Their Spatial Relationship to DDX1 Bodies, Cajal Bodies, and Gems

    Science.gov (United States)

    Li, Lei; Roy, Ken; Katyal, Sachin; Sun, Xuejun; Bléoo, Stacey; Godbout, Roseline

    2006-01-01

    DDX1 bodies, cleavage bodies, Cajal bodies (CBs), and gems are nuclear suborganelles that contain factors involved in RNA transcription and/or processing. Although all four nuclear bodies can exist as distinct entities, they often colocalize or overlap with each other. To better understand the relationship between these four nuclear bodies, we examined their spatial distribution as a function of the cell cycle. Here, we report that whereas DDX1 bodies, CBs and gems are present throughout interphase, CPSF-100-containing cleavage bodies are predominantly found during S and G2 phases, whereas CstF-64-containing cleavage bodies are primarily observed during S phase. All four nuclear bodies associate with each other during S phase, with cleavage bodies colocalizing with DDX1 bodies, and cleavage bodies/DDX1 bodies residing adjacent to gems and CBs. Although inhibitors of RNA transcription had no effect on DDX1 bodies or cleavage bodies, inhibitors of DNA replication resulted in loss of CstF-64-containing cleavage bodies. A striking effect on nuclear structures was observed with latrunculin B, an inhibitor of actin polymerization, resulting in the formation of needlelike nuclear spicules made up of CstF-64, CPSF-100, RNA, and RNA polymerase II. Our results suggest that cleavage body components are highly dynamic in nature. PMID:16371507

  12. The Evolutionary Behavior of Old Novae in their Quiescent Stage: DN Gem, T Aur and HR Lyr

    Science.gov (United States)

    Findlay, Amanda M.; Gropp, Jeffrey; Hause, Connor; Sion, Edward M.

    2016-01-01

    There is currently a poor understanding about how a nova explosion affects the rate of mass transfer in a cataclysmic binary system and the subsequent evolutionary behavior of the accreting white dwarf during post-nova quiescence. In order to shed light on this fundamental question, we have carried out a synthetic spectral analysis of the archival HST and IUE far ultraviolet spectra of the post-novae, DN Gem (Nova Gem 1912), T Aur (Nova Aur 1891) and HR Lyrae (Nova Lyr 1919). We have utilized the best available input parameters from the literature for the white dwarf masses, orbital inclinations and distances of each system while adopting the newly determined interstellar reddening corrections, E(B-V), of Selvelli and Gilmozzi (2013). Our synthetic spectral analysis utilized optically thick, steady state accretion disk models and white dwarf model atmospheres that we constructed using TLUSTY and SYNSPEC (Hubeny 1988, Hubeny and Lanz 1995). We report the results of our model fitting including the mass transfer rates and other physical properties 115 years (DN Gem), 124 years (T Aur) and 96 years (HR Lyra) after their respective nova explosions.This work is supported by NASA grants NNX13AF12G to Villanova University and a summerundergraduate research assistantship from the NASA-DSGC.

  13. Ion space-charge effects in multi-GEM detectors: challenges and possible solutions for future applications

    CERN Document Server

    AUTHOR|(CDS)2079251; Streli, Christina

    Gaseous Electron Multiplier (GEM) detectors are well known both for stable operation under irradiation with high particle fluxes and high achievable effective gains. The aim of this thesis is two-fold: to investigate the limits of GEM detector operation due to space-charge effects, and to develop a means to reduce the magnitude of the observed effects and thus extend those limitations. The first part of the thesis presents a comprehensive study of the intrinsic limits of triple-GEM detectors under exposure to very high fluxes of soft X-rays or operation at very large effective gains. The behaviour of the effective gain, ion back-flow and the pulse-height spectra is explained in terms of the movement and accumulation of positive ions throughout the detector volume, resulting in distortions of the transfer and amplification fields. Numerical computations, and measurements on double-stage and single-stage detectors confirm the model describing the observed effects. Discussions on ways to extend the limits of gas...

  14. Construction and Performance of Large-Area Triple-GEM Prototypes for Future Upgrades of the CMS Forward Muon System

    CERN Document Server

    AUTHOR|(CDS)2068936; Marinov, A.; Zaganidis, N.; Ban, Y.; Cai, J.; Teng, H.; Mohapatra, A.; Moulik, T.; Abbrescia, M.; Colaleo, A.; de Robertis, G.; Loddo, F.; Maggi, M.; Nuzzo, S.; Tupputi, S.A.; Benussi, L.; Bianco, S.; Colafranceschi, S.; Piccolo, D.; Raffone, G.; Saviano, G.; Bagliesi, M.G.; Cecchi, R.; Magazzu, G.; Oliveri, E.; Turini, N.; Fruboes, T.; Abbaneo, D.; Armagnaud, C.; Aspell, P.; Bally, S.; Berzano, U.; Bos, J.; Bunkowski, K.; Chatelain, J.P.; Christiansen, J.; Conde Garcia, A.; David, E.; De Oliveira, R.; Duarte Pinto, S.; Ferry, S.; Formenti, F.; Franconi, L.; Marchioro, A.; Mehta, K.; Merlin, J.; Nemallapudi, M.V.; Postema, H.; Rodrigues, A.; Ropelewski, L.; Sharma, A.; Smilkjovic, N.; Villa, M.; Zientek, M.; Gutierrez, A.; Karchin, P.E.; Gnanvo, K.; Hohlmann, M.; Staib, M.J.

    2011-01-01

    At present, part of the forward RPC muon system of the CMS detector at the CERN LHC remains uninstrumented in the high-\\eta region. An international collaboration is investigating the possibility of covering the 1.6 < |\\eta| < 2.4 region of the muon endcaps with large-area triple-GEM detectors. Given their good spatial resolution, high rate capability, and radiation hardness, these micro-pattern gas detectors are an appealing option for simultaneously enhancing muon tracking and triggering capabilities in a future upgrade of the CMS detector. A general overview of this feasibility study will be presented. The design and construction of small (10\\times10 cm2) and full-size trapezoidal (1\\times0.5 m2) triple-GEM prototypes will be described. During detector assembly, different techniques for stretching the GEM foils were tested. Results from measurements with x-rays and from test beam campaigns at the CERN SPS will be shown for the small and large prototypes. Preliminary simulation studies on the expected...

  15. Performance of a large size triple GEM detector at high particle rate for the CBM Experiment at FAIR

    Science.gov (United States)

    Adak, Rama Prasad; Kumar, Ajit; Dubey, Anand Kumar; Chattopadhyay, Subhasis; Das, Supriya; Raha, Sibaji; Samanta, Subhasis; Saini, Jogender

    2017-02-01

    In CBM Experiment at FAIR, dimuons will be detected by a Muon Chamber (MUCH) consisting of segmented absorbers of varying widths and tracking chambers sandwiched between the absorber-pairs. In this fixed target heavy-ion collision experiment, operating at highest interaction rate of 10 MHz for Au+Au collision, the inner region of the 1st detector will face a particle rate of 1 MHz/cm2. To operate at such a high particle density, GEM technology based detectors have been selected for the first two stations of MUCH. We have reported earlier the performance of several small-size GEM detector prototypes built at VECC for use in MUCH. In this work, we report on a large GEM prototype tested with proton beam of momentum 2.36 GeV/c at COSY-Jülich Germany. The detector was read out using nXYTER operated in self-triggering mode. An efficiency higher than 96% at ΔVGEM = 375.2 V was achieved. The variation of efficiency with the rate of incoming protons has been found to vary within 2% when tested up to a maximum rate of 2.8 MHz/cm2. The gain was found to be stable at high particle rate with a maximum variation of ∼9%.

  16. Performance of a large size triple GEM detector at high particle rate for CBM Experiment at FAIR

    CERN Document Server

    Adak, Rama Prasad; Dubey, A K; Samanta, Subhasis; Saini, J; Das, S; Raha, S; Chattopadhyay, Subhasis

    2016-01-01

    In CBM experiment dimuon will be detected by a Muon Chamber (MUCH) consisting of segmented absorbers of varying widths and of tracking chambers sandwiched between the absorber-pairs. In this fixed target experiment operating at the highest interaction rate of $~10~MHz$, the first tracking chamber in its inner radial ring will face a particle rate of $400 kHz/cm^2$. To operate at such a high particle density, GEM technology based detectors have been chosen for the first two stations of MUCH. We have reported earlier the performance of several small-size GEM detector prototypes built at VECC for use in MUCH. A real-size GEM prototype has been tested using proton beam of momentum $2.36 ~GeV/c$ at COSY- Juelich, Germany. The detector was read out using nXYTER ASIC operated in self-triggering mode. An efficiency of the detector higher than $96\\%$ has been achieved. Variation of efficiency with the rate of incoming protons when tested at the highest rate of 1.5 MHz/cm$^2$ has been found to vary within $~2\\%$. The g...

  17. Fusion Science Outreach at the MIT Plasma Science and Fusion Center

    Science.gov (United States)

    Censabella, V.; Rivenberg, P.; Granville, J.; Nachtrieb, R.; Gangadhara, S.

    1997-11-01

    Educational Outreach at the MIT Plasma Science and Fusion Center is organized and energized by volunteers working together to increase the public's knowledge of fusion and plasma-related experiments. The PSFC holds a number of outreach activities throughout the year, such as Middle and High School Outreach Days. Included in these days is a demonstration of how magnets affect plasma using the ``Plasma Demo," an educational tool which will be on display for the first time outside the MIT area. Also featured is ``C-Mod Jr.," a video game which helps students discover how computers manipulate magnetic pulses to keep a plasma confined in the C-Mod tokamak for as long as possible. The PSFC maintains a Home Page on the World Wide Web, which can be reached at HTTP://PFC.MIT.EDU.

  18. MIT Clean Energy Prize: Final Technical Report May 12, 2010 - May 11, 2011

    Energy Technology Data Exchange (ETDEWEB)

    Snyder, Chris [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Campbell, Georgina [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Salony, Jason [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States); Aulet, Bill [Massachusetts Inst. of Technology (MIT), Cambridge, MA (United States)

    2011-08-09

    The MIT Clean Energy Prize (MIT CEP) is a venture creation and innovation competition to encourage innovation in the energy space, specifically with regard to clean energy. The Competition invited student teams from any US university to submit student-led ventures that demonstrate a high potential of successfully making clean energy more affordable, with a positive impact on the environment. By focusing on student ventures, the MIT CEP aims to educate the next generation of clean energy entrepreneurs. Teams receive valuable mentoring and hard deadlines that complement the cash prize to accelerate development of ventures. The competition is a year-long educational process that culminates in the selection of five category finalists and a Grand Prize winner and the distribution of cash prizes to each of those teams. Each entry was submitted in one of five clean energy categories: Renewables, Clean Non-Renewables, Energy Efficiency, Transportation, and Deployment.

  19. Hyperhomocysteinämie bei Patienten mit koronarer Herzkrankheit vor aortokoronarer Bypass-Operation (CABG

    Directory of Open Access Journals (Sweden)

    Stanger O

    1999-01-01

    Full Text Available Erhöhte Plasmakonzentrationen der schwefelhaltigen Aminosäure Homocystein (Hcy wurden mit einer frühzeitigen Entwicklung arteriosklerotischer Gefäßveränderungen, thromboembolischer Komplikationen und schlechter Prognose der koronaren Herzkrankheit (KHK in Verbindung gebracht. Um das Vorkommen einer Hyperhomocysteinämie und die Wertigkeit des oralen Methionin-Belastungs-Tests (oMBT bei Patienten mit angiographisch nachgewiesener koronaren Herzkrankheit unmittelbar vor einer geplanten aortokoronaren Bypass-Operation (CABG zu untersuchen, wurde bei 150 KHK-Patienten und 80 gesunden Kontrollen nüchtern und 6 Stunden nach Methionin-Belastung totales Homocystein (tHcy im Plasma gemessen, ebenso u. a. Folsäure (Plasma und die Vitamine B6 und B12. Insgesamt hatten 32 % der Patienten eine Hyperhomocysteinämie. Die Höhe von Homocystein korrelierte dabei signifikant mit der Folsäure, ebenso der Anstieg unter Belastung und grenzwertig mit dem Body Mass Index (BMI. Ein solcher Zusammenhang konnte nicht für die Vitamine B6, B12 sowie Cholesterin, Triglyceride und Fibrinogen beobachtet werden. 37% der Patienten mit erhöhten Hcy-Werten wurden nur durch den Einsatz des oMBT erkannt. Daraus schließen wir, daß die Prävalenz einer Hyperhomocysteinämie in der untersuchten Patientengruppe im Vergleich zu einer gesunden Population sehr hoch ist. Der orale Methionin-Belastungs-Test stellt ein wichtiges Mittel zur Identifizierung von Patienten mit Hyperhomocysteinämie dar, dessen Einsatz den Aufwand rechtfertigt.

  20. Parallel substrate monitoring in small-volume bioreactors; Parallele Substratkontrolle in Bioreaktoren mit geringem Volumen

    Energy Technology Data Exchange (ETDEWEB)

    Wolfram, E.P.

    2002-05-01

    In the first developmental phase of microbial processes, relevant parameters for reaction engineering are investigated and optimized with parallel experiments in small reactors (shake flask scale). Substrate concentrations are central process parameters. Their control might help to increase efficiency and quality of this developmental phase. Thus, a parallel, automatic and sterile sampling technique with hollow fiber membranes was developed that suits the small reaction volume. The parallel sampling modules were connected to a substrate analysis system. The combination of the analytical technique with a controller and a precise microdosing system for substrate closed the control loop. The prototype device was characterized and its suitability for online monitoring and control of bioprocesses confirmed. This technique allows for the first time online measurement and control of substrate concentrations in parallel bioreactions (i.e. with Escherichia coli) with measuring rates of the order of minutes. (orig.) [German] Mikrobielle Prozesse werden in der ersten Entwicklungsphase in Parallelexperimenten in Kleinreaktoren (Schuettelkolben-Massstab) reaktionstechnisch untersucht und optimiert. Substratkonzentrationen sind dabei eine zentrale Prozessgroesse, deren Kontrolle zur Steigerung der Effizienz und Qualitaet dieser Entwicklungsphase beitragen kann. Daher wurde eine fuer kleine Reaktionsvolumen geeignete parallele, automatische und sterile Probenahmetechnik mit Hohlfaser-Dialysemembranen entwickelt und mit einem Substrat-Analysesystem gekoppelt. Durch Kombination der Messtechnik mit einem Regler und einem praezisen Mikrodosiersystem fuer Substrat wurde der Regelkreis geschlossen. Das Funktionsmuster wurde verfahrenstechnisch charakterisiert und seine Eignung zur Online-Ueberwachung und Regelung von Bioprozessen untersucht. Mit dieser Technik gelang erstmals die Messung und Regelung von Substratkonzentrationen in parallel durchgefuehrten Bioreaktionen (beispielsweise

  1. Prolongierte iktale Hemiparese und Aphasie in Kombination mit PLEDs im EEG: ein Fallbericht

    Directory of Open Access Journals (Sweden)

    Leutmezer F

    2002-01-01

    Full Text Available Eine 89jährige Patientin wurde wegen eines konvulsiven Status epilepticus an einer internen Abteilung aufgenommen. In der Anamnese finden sich ein Zustand nach ischämischem Insult links hoch-parietal (2 Jahre vor Aufnahme, ein Zustand nach intrazerebraler Blutung in das Infarktareal (1 Jahr vor Aufnahme mit konsekutiver symptomatischer Epilepsie, die mit Lamotrigin gut eingestellt war, sowie ein chronisches, normofrequentes Vorhofflimmern. Anhand unseres Fallberichtes möchten wir mehrere Aspekte, die unserer Ansicht nach zum Teil von klinischer, zum Teil von theoretischer Bedeutung sind, herausstreichen.

  2. Telemedizin in der Sekundärprävention: ein Feldversuch mit asthmakranken Jugendlichen

    OpenAIRE

    Huber, Thomas; Diemer, Robert; Kreuzer, Johannes

    2008-01-01

    Die Führung eines Asthma-Tagebuchs erfordert gerade von erkrankten Kindern und Jugendlichen sehr viel Disziplin. So sollen mehrmals täglich Peak-Flow-Werte mit Uhrzeit und Datum, eingenommene Medikamente und eventuell aufgetretene Beschwerden notiert werden, um den behandelnden Ärzten bessere Betreuungs- und Therapiemöglichkeiten zu bieten. In diesem Beitrag wird die Problematik erläutert und aufgezeigt, wie mit Hilfe einer mobilen Anwendung von InprimoTM versucht wird, die Compliance der jun...

  3. Langzeiteffekte der FM-Versorgung bei Kindern mit AVWS, Subtyp "Auditive Selektionsstörung"

    OpenAIRE

    Braun, S.; Schönweiler, R

    2010-01-01

    Hintergrund: Auditive Verarbeitungs- und/oder Wahrnehmungsstörungen können mit Übungstherapie, Kompensationsstrategien und mit akustischen Maßnahmen behandelt werden . FM-Anlagen gehören zu den "aktiven" akustischen Maßnahmen, für die mehr Studien zum Wirkungsnachweis wünschenswert sind. Auf der Jahrestagung der DGPP 2007 haben wir bereits über kurzfristige Effekte berichtet .Material und Methoden: In der vorliegenenden Arbeit haben wir die Studie als prospektive Einzelfallstudie fortgefüh...

  4. wienXtra-jugendinfo rat&hilfe Forum. Erfahrungen aus vier Jahren mit einem moderierten Jugendforum

    Directory of Open Access Journals (Sweden)

    Alexander Brunner

    2005-09-01

    Full Text Available Im Artikel werden die Erfahrungen aus der Arbeit mit einem moderierten Jugendforum dargestellt. Neben den Entwicklungen über die Jahre werden Themen wie Moderation, Communitybildung, Flaming, Registrierung etc. exemplarisch am rat&hilfe Forum veranschaulicht und reflektiert. So werden einerseits Einblicke in die praktischen Erfahrungen und die praktische Arbeit mit und in einem Jugendforum ermöglicht und anderseits bestimmte Phänomene in einer erweiterten und verallgemeinerten Form reflektiert. Auf diese Art und Weise können diese spezifischen Erfahrungen für ähnliche Projekte fruchtbare Anregungen bieten.

  5. GEM-based TPC with CCD Imaging for Directional Dark Matter Detection

    CERN Document Server

    Phan, N S; Lee, E R; Loomba, D; Matthews, J A J; Miller, E H

    2015-01-01

    Directional dark matter detection will require scale-ups to large volumes if low-pressure gas Time Projection Chambers (TPCs) are the only viable technology. We discuss some of the challenges for this technology, where balancing the goal of achieving the best sensitivity with that of cost effective scale-up requires an optimization over a large parameter space. Critical for this are the precision measurements of the fundamental properties of both electron and nuclear recoil tracks down to the lowest energies. Such measurements would provide a benchmark for background discrimination and directional sensitivity that could be used for future optimization studies for directional dark matter experiments. In this paper we describe a small, high resolution, high signal-to-noise GEM-based TPC with a 2D CCD readout designed for this goal. The performance of the detector was characterized using X-rays, gamma-rays, and neutrons, enabling detailed measurements of electron and nuclear recoil tracks. Stable effective gas g...

  6. PLC-controlled cryostats for the BlackGEM and MeerLICHT detectors

    CERN Document Server

    Raskin, Gert; Pessemier, Wim; Bloemen, Steven; Klein-Wolt, Marc; Roelfsema, Ronald; Groot, Paul; Aerts, Conny

    2016-01-01

    BlackGEM (BG) is an array of telescopes, currently under development at the Radboud University Nijmegen and at NOVA. It targets the detection of the optical counterparts of gravitational waves. The first 3 BG telescopes are planned to be installed in 2018 at the La Silla observatory. A single prototype telescope, named MeerLICHT, will already be commissioned early 2017 in Sutherland to provide an optical complement for the MeerKAT radio array. The BG array consists of, initially, a set of 3 robotic 65-cm wide-field telescopes. Each telescope is equipped with a single STA1600 CCD detector with 10.5k x 10.5k 9-mum pixels that covers a 2.7 square degrees field of view. The cryostats for housing these detectors are developed and built at the KU Leuven University. The operational model of BG requires long periods of reliable ands-off operation. Therefore, we designed the cryostats for long vacuum hold time and we make use of a closed-cycle cooling system, based on Polycold PCC Joule-Thomson coolers. A single progr...

  7. First performance of the GeMS + GMOS system - 1. Imaging

    Science.gov (United States)

    Hibon, Pascale; Garrel, Vincent; Neichel, Benoit; Prout, Benjamin; Rigaut, Francois; Koning, Alice; Carrasco, Eleazar R.; Gimeno, German; Pessev, Peter

    2016-09-01

    During the commissioning of the Gemini MCAO System (GeMS), we had the opportunity to obtain data with the Gemini Multi-Object Spectrograph (GMOS), the most utilized instrument at Gemini South Observatory, in 2012 March and May. Several globular clusters were observed in imaging mode that allowed us to study the performance of this new and untested combination. GMOS is a visible instrument, hence pushing MCAO towards the visible. We report here on the results with the GMOS instruments, derive photometric performance in term of full width at half-maximum (FWHM) and throughput. In most of the cases, we obtained an improvement factor of at least 2 against the natural seeing. This result also depends on the natural guide star constellation selected for the observations and we then study the impact of the guide star selection on the FWHM performance. We also derive a first astrometric analysis showing that the GeMS+GMOS system provide an absolute astrometric precision better than 8 mas and a relative astrometric precision lower than 50 mas.

  8. Fault-tolerant drive electronics for a Xinetics deformable mirror at GeMS DM0

    Science.gov (United States)

    Barberio, Michael J.

    2016-07-01

    Gemini South is replacing one of the (3) CILAS DMs with a 349-actuator Xinetics DM in its GeMS MCAO system. Xinetics mirrors operate over a 40-100V dynamic range and require that inter-actuator stroke differences are limited to half-scale; each actuator must be within 30V of its neighbor to prevent mechanical stress and possible face sheet separation. A robust way to implement this protection is to use high power transient voltage suppressors (TVSs) as a 2D-mesh between the amplifiers and mirror, but this has system implications. A sustained clamp condition dissipates significant power in the devices, and if an actuator fails as short (which occurred once with the DM in a thermal chamber), the system is subject to a cascade failure event as multiple outputs drive the shorted actuator through the TVS network. This latter risk is readily resolved by using series fuses to the DM. In this third-generation driver, current sensing and logic inhibit amplifier outputs after a sustained TVS clamp condition or shorted output, and LED indicators show the location. Redundant thermal sensing is used on modular TVS row and column boards. A second 2D-mesh of high impedance resistors after the fuses will hold an unpowered channel to the average voltage of its neighbors, with a negligible influence function. A Failure Modes and Effects Analysis shows significant fault tolerance.

  9. Vanadium-rich ruby and sapphire within Mogok Gemfield, Myanmar: implications for gem color and genesis

    Science.gov (United States)

    Zaw, Khin; Sutherland, Lin; Yui, Tzen-Fu; Meffre, Sebastien; Thu, Kyaw

    2015-01-01

    Rubies and sapphires are of both scientific and commercial interest. These gemstones are corundum colored by transition elements within the alumina crystal lattice: Cr3+ yields red in ruby and Fe2+, Fe3+, and Ti4+ ionic interactions color sapphires. A minor ion, V3+ induces slate to purple colors and color change in some sapphires, but its role in coloring rubies remains enigmatic. Trace element and oxygen isotope composition provide genetic signatures for natural corundum and assist geographic typing. Here, we show that V can dominate chromophore contents in Mogok ruby suites. This raises implications for their color quality, enhancement treatments, geographic origin, exploration and exploitation and their comparison with rubies elsewhere. Precise LA-ICP-MS analysis of ruby and sapphire from Mogok placer and in situ deposits reveal that V can exceed 5,000 ppm, giving V/Cr, V/Fe and V/Ti ratios up to 26, 78, and 97 respectively. Such values significantly exceed those found elsewhere suggesting a localized geological control on V-rich ruby distribution. Our results demonstrate that detailed geochemical studies of ruby suites reveal that V is a potential ruby tracer, encourage comparisons of V/Cr-variation between ruby suites and widen the scope for geographic typing and genesis of ruby. This will allow more precise comparison of Asian and other ruby fields and assist confirmation of Mogok sources for rubies in historical and contemporary gems and jewelry.

  10. Performance of a Large-area GEM Detector Read Out with Wide Radial Zigzag Strip

    CERN Document Server

    Zhang, Aiwu; Hansen, Eric; Hohlmann, Marcus; Khanal, Shreeya; Phipps, Michael; Starling, Elizabeth; Twigger, Jessie; Walton, Kimberly

    2015-01-01

    A 1-meter-long trapezoidal Triple-GEM detector with wide readout strips was tested in hadron beams at the Fermilab Test Beam Facility in October 2013. The readout strips have a special zigzag geometry and run along the radial direction with an azimuthal pitch of 1.37 mrad to measure the azimuthal phi-coordinate of incident particles. The zigzag geometry of the readout reduces the required number of electronic channels by a factor of three compared to conventional straight readout strips while preserving good angular resolution. The average crosstalk between zigzag strips is measured to be an acceptable 5.5%. The detection efficiency of the detector is (98.4+-0.2)%. When the non-linearity of the zigzag-strip response is corrected with track information, the angular resolution is measured to be (193+-3) urad, which corresponds to 14% of the angular strip pitch. Multiple Coulomb scattering effects are fully taken into account in the data analysis with the help of a stand-alone Geant4 simulation that estimates in...

  11. J-GEM Follow-Up Observations of The Gravitational Wave Source GW151226

    CERN Document Server

    Yoshida, Michitoshi; Tominaga, Nozomu; Morokuma, Tomoki; Tanaka, Masaomi; Asakura, Yuichiro; Matsubayashi, Kazuya; Ohta, Kouji; Abe, Fumio; Chimasu, Sho; Furusawa, Hisanori; Itoh, Ryosuke; Itoh, Yoichi; Kanda, Yuka; Kawabata, Koji S; Kawabata, Miho; Koshida, Shintaro; Koshimoto, Naoki; Kuroda, Daisuke; Moritani, Yuki; Motohara, Kentaro; Murata, Katsuhiro L; Nagayama, Takahiro; Nakaoka, Tatsuya; Nakata, Fumiaki; Nishioka, Tsubasa; Saito, Yoshihiko; Terai, Tsuyoshi; Tristram, Paul J; Yanagisawa, Kenshi; Yasuda, Naoki; Doi, Mamoru; Fujisawa, Kenta; Kawachi, Akiko; Kawai, Nobuyuki; Tamura, Yoichi; Uemura, Makoto; Yatsu, Yoichi

    2016-01-01

    We report the results of optical--infrared follow-up observations of the gravitational wave (GW) event GW151226 detected by the Advanced LIGO in the framework of J-GEM (Japanese collaboration for Gravitational wave ElectroMagnetic follow-up). We performed wide-field optical imaging surveys with Kiso Wide Field Camera (KWFC), Hyper Suprime-Cam (HSC), and MOA-cam3. The KWFC survey started at 2.26 days after the GW event and covered 778 deg$^2$ centered at the high Galactic region of the skymap of GW151226. We started the HSC follow-up observations from 12 days after the event and covered an area of 63.5 deg$^2$ of the highest probability region of the northern sky with the limiting magnitudes of 24.6 and 23.8 for i band and z band, respectively. MOA-cam3 covered 145 deg$^2$ of the skymap with MOA-red filter 2.5 months after the GW alert. Total area covered by the wide-field surveys was 986.5 deg$^2$. The integrated detection probability of all the observed area was $\\sim$29%. We also performed galaxy-targeted o...

  12. Impact of famous CEDAR, GEM and ISTP geomagnetic Storms on HF Radio Propagation

    Science.gov (United States)

    Blagoveshchensky, D.; Sergeeva, M.

    The mighty geomagnetic storms due to the extraordinary Sun s activity cause as a rule some impacts in these areas radiation effects on human and satellites commercial airlines outages electric power and other geomagnetic effects navigation and communication GPS effects ionospheric disturbances HF communication effects Therefore our scientific understanding of this activity is very important Joint efforts for example within the framework of the CAWSES enable progress in our ability to i identify critical inputs to specify the geospace environment at a level needed to minimize impacts on technology human society and life and ii support the development of robust models that predict conditions in geospace based on understanding of the Sun-Earth system and all of its interacting components In this study influence of 14 geomagnetic storms from a list of CEDAR GEM and ISTP storms within 1997-99 on radio propagation conditions have been investigated These conditions were estimated through variations of the MOF and LOF the maximum and lowest operation frequencies on each path from three high-latitude HF radio paths of North-west Russia before during and after a storm It was shown that the storm impact on the ionosphere and radio propagation for each storm has an individual character Nevertheless the common character of the certain manifestations during storm-time was revealed For example the frequency range MOF - LOF is getting wider several hours before a storm then it is sharply narrow during a storm-time and further it is expanded again several

  13. A new front-end ASIC for GEM detectors with time and charge measurement capabilities

    Science.gov (United States)

    Ciciriello, F.; Corsi, F.; De Robertis, G.; Felici, G.; Loddo, F.; Marzocca, C.; Matarrese, G.; Ranieri, A.

    2016-07-01

    A 32 channel CMOS front-end ASIC has been designed to read out the GEM detectors intended to be used for beam monitoring in a new proton-therapy facility currently under construction. In order to improve the spatial resolution by exploiting charge centroid algorithms, the analog channels, based on the classic CSA+shaper architecture, are equipped with a peak detector (PD) which works as an analog memory during the read-out phase. The outputs of the PDs are multiplexed towards an integrated 8-bit subranging ADC. An accurate trigger signal marks the arrival of a valid event and is generated by fast-ORing the outputs of 32 voltage discriminators which compare the shaper outputs with a programmable threshold. The digital part of the ASIC manages the read-out of the channels, the A/D conversion and the configuration of the ASIC. A 100 Mbit/s LVDS serial link is used for data communication. The sensitivity of the analog channel is 15 mV/fC and the dynamic range is 80 fC. The simulated ENC is about 650 e- for a detector capacitance of 10 pF. © 2001 Elsevier Science. All rights reserved

  14. GeMS MCAO observations of the Galactic globular cluster NGC 2808: the absolute age

    CERN Document Server

    Massari, Davide; McConnachie, A; Bono, G; Dall'Ora, M; Ferraro, I; Iannicola, G; Stetson, P B; Turri, P; Tolstoy, E

    2016-01-01

    Globular clusters are the oldest stellar systems in the Milky Way and probe the early epoch of the Galaxy formation. However, the uncertainties on their absolute age are still too large to soundly constrain how the Galactic structures have assembled. The aim of this work is to obtain an accurate estimate of the absolute age of the globular cluster NGC 2808 using deep IR data obtained with the multi conjugate adaptive optics system operating at the Gemini South telescope (GeMS). This exquisite photometry, combined with that obtained in V and I bands with HST, allowed us the detection of the faint Main Sequence Knee feature in NGC 2808 colour magnitude diagram. The difference between this point and the main sequence turn off is a good age estimator and provides ages with unprecedented accuracy. We found that NGC 2808 has an age of t=10.9\\pm0.7 (intrinsic) \\pm0.45 (metallicity term) Gyr. A possible contamination by He-enhanced population could make the cluster up to 0.25 Gyr older. Although this age estimate agr...

  15. A new front-end ASIC for GEM detectors with time and charge measurement capabilities

    Energy Technology Data Exchange (ETDEWEB)

    Ciciriello, F., E-mail: fabio.ciciriello@poliba.it [DEI-Politecnico di Bari, Via Orabona 4, I-70125 Bari (Italy); INFN, Sezione di Bari, Via Orabona 4, I-70125 Bari (Italy); Corsi, F. [DEI-Politecnico di Bari, Via Orabona 4, I-70125 Bari (Italy); INFN, Sezione di Bari, Via Orabona 4, I-70125 Bari (Italy); De Robertis, G. [INFN, Sezione di Bari, Via Orabona 4, I-70125 Bari (Italy); Felici, G. [INFN, Laboratori Nazionali di Frascati, Via E. Fermi 40, I-00044 Frascati (Italy); Loddo, F. [INFN, Sezione di Bari, Via Orabona 4, I-70125 Bari (Italy); Marzocca, C.; Matarrese, G. [DEI-Politecnico di Bari, Via Orabona 4, I-70125 Bari (Italy); INFN, Sezione di Bari, Via Orabona 4, I-70125 Bari (Italy); Ranieri, A. [INFN, Sezione di Bari, Via Orabona 4, I-70125 Bari (Italy)

    2016-07-11

    A 32 channel CMOS front-end ASIC has been designed to read out the GEM detectors intended to be used for beam monitoring in a new proton-therapy facility currently under construction. In order to improve the spatial resolution by exploiting charge centroid algorithms, the analog channels, based on the classic CSA+shaper architecture, are equipped with a peak detector (PD) which works as an analog memory during the read-out phase. The outputs of the PDs are multiplexed towards an integrated 8-bit subranging ADC. An accurate trigger signal marks the arrival of a valid event and is generated by fast-ORing the outputs of 32 voltage discriminators which compare the shaper outputs with a programmable threshold. The digital part of the ASIC manages the read-out of the channels, the A/D conversion and the configuration of the ASIC. A 100 Mbit/s LVDS serial link is used for data communication. The sensitivity of the analog channel is 15 mV/fC and the dynamic range is 80 fC. The simulated ENC is about 650 e{sup −} for a detector capacitance of 10 pF. © 2001 Elsevier Science. All rights reserved.

  16. Study of reconstruction methods for a time projection chamber with GEM gas amplification system

    Energy Technology Data Exchange (ETDEWEB)

    Diener, R.

    2006-12-15

    A new e{sup +}e{sup -} linear collider with an energy range up to 1TeV is planned in an international collaboration: the International Linear Collider (ILC). This collider will be able to do precision measurements of the Higgs particle and of physics beyond the Standard Model. In the Large Detector Concept (LDC) - which is one proposal for a detector at the ILC - a Time Projection Chamber (TPC) is foreseen as the main tracking device. To meet the requirements on the resolution and to be able to work in the environment at the ILC, the application of new gas amplification technologies in the TPC is necessary. One option is an amplification system based on Gas Electron Multipliers (GEMs). Due to the - in comparison with older technologies - small spatial width of the signals, this technology poses new requirements on the readout structures and the reconstruction methods. In this work, the performance and the systematics of different reconstruction methods have been studied, based on data measured with a TPC prototype in high magnetic fields of up to 4T and data from a Monte Carlo simulation. The latest results of the achievable point resolution are presented and their limitations have been investigated. (orig.)

  17. The GEM detectors for the innermost region of the forward muon station of the LHCb experiment

    CERN Document Server

    Alfonsi, M

    The LHCb experiment will take place at the LHC accelerator at CERN and will start in 2008. It is dedicated to precision measurements of CP violation and rare decays in the b quark sec- tor. The apparatus is a single arm spectrometer and it is designed with a robust and flexible trigger in order to extensively gain access to a wide spread of differ ent physical processes involving beauty particles. This will allow to over-constrain the Standard M odel predictions about CP violation, and to discover any possible inconsistency, whi ch would reveal the presence of “New Physics” beyond the Standard Model. This thesis reports the work performed on two aspects of the L HCb experiment: the main contribution is the development and the construction of a de tector based on Gas Electron Multiplier (GEM) technology for the instrumentation of the high irradiated region around the beam pipe of the forward Muon Station; in the second part t he possibility of the search of the rare D 0 → + − decay at the LHCb exper...

  18. Spectroscopic study of inclusions in gem corundum from Mercaderes, Cauca, Colombia

    Science.gov (United States)

    Zeug, Manuela; Rodríguez Vargas, Andrés Ignacio; Nasdala, Lutz

    2016-10-01

    Mineral inclusions in gem corundum from Mercaderes, Cauca, Colombia, were investigated non-destructively using Raman and photoluminescence spectroscopy, with special focus lying on phases containing radioactive elements. Besides abundant rutile, the minerals zircon, apatite, feldspar, and an epidote-group species, most probably allanite-(Ce), were found. The latter is detected easily from its characteristic Nd3+ emission pattern, which may prove useful in future provenance studies. Zircon inclusions range from well crystalline to moderately radiation damaged [FWHM (full width at half band maximum) of the ν 3(SiO4) Raman band 1.8-10.9 cm-1]. Both the zircon inclusions and their neighbouring host corundum are affected by compressive stress, which is assigned to (1) heterogeneous volume expansion of the host-inclusion couple upon pressure release during the uplift following primary growth and (2) volume expansion of the zircon inclusion due to the accumulation of self-irradiation damage. Internal stress of zircon inclusions averages 1.1 GPa. Heat treatment of corundum leads to structural reconstitution of zircon (narrowed zircon Raman bands with FWHMs in the range 1.8-2.7 cm-1) and accompanying stress release in the adjacent corundum (indicated by downshifts of the R 1 emission of Cr3+). The observation of broadened Raman band of zircon inclusions therefore allows one to exclude high-temperature enhancement of the host corundum.

  19. A Triple-GEM Detector with Pixel Readout for High-Rate Beam Tracking in COMPASS

    CERN Document Server

    Nagel, T; Haas, F; Ketzer, B; Konorov, I; Krämer, M; Mann, A; Paul, S

    2008-01-01

    For its physics program with a high-intensity hadron beam of $2 · 10^{7}$ particles/s, the COMPASS experiment at CERN requires tracking of charged particles scattered by very small angles with respect to the incident beam direction. While good resolution in time and space is mandatory, the challenge is imposed by the high beam intensity, requiring radiation-hard detectors which add very little material to the beam path in order to minimise secondary interactions. To this end, a set of triple-GEM detectors with pixel readout in the beam region and 2-D strip readout in the periphery is currently being built. The pixel size has been chosen to be 1×1 mm2, which constitutes a compromise between the spatial resolution achievable and the number of readout channels. Surrounding the pixel area, a 2-D strip readout with a pitch of 400 μm has been realised on the same printed circuit foil. In total an active area of 10 × 10 cm2 is covered using 2048 readout channels. Analogue readout by the APV25 ASIC has been chose...

  20. Kepler Observations of V447 Lyr: An Eclipsing U Gem Cataclysmic Variable

    CERN Document Server

    Ramsay, Gavin; Howell, Steve B; Wood, Matt A; Still, Martin; Barclay, Thomas; Smale, Alan

    2012-01-01

    We present the results of an analysis of data covering 1.5 years of the dwarf nova V447 Lyr. We detect eclipses of the accretion disk by the mass donating secondary star every 3.74 hrs which is the binary orbital period. V447 Lyr is therefore the first dwarf nova in the Kepler field to show eclipses. We also detect five long outbursts and six short outbursts showing V447 Lyr is a U Gem type dwarf nova. We show that the orbital phase of the mid-eclipse occurs earlier during outbursts compared to quiescence and that the width of the eclipse is greater during outburst. This suggests that the bright spot is more prominent during quiescence and that the disk is larger during outburst than quiescence. This is consistent with an expansion of the outer disk radius due to the presence of high viscosity material associated with the outburst, followed by a contraction in quiescence due to the accretion of low angular momentum material. We note that the long outbursts appear to be triggered by a short outburst, which is ...

  1. Antimicrobial Activity of Hydroxylactone obtained by Biotransformation of Bromo- and Iodolactone with Gem-Dimethylcyclohexane Ring

    Energy Technology Data Exchange (ETDEWEB)

    Grabarczyk, Malgorzata; Maczka, Wanda; Winska, Katarzyna; Aniol, Miroslaw, E-mail: magrab@onet.pl [Department of Chemistry, Wroclaw University of Environmental and Life Sciences, Wroclaw (Poland); Zarowska, Barbara [Department of Biotechnology and Food Microbiology, Wroclaw University of Environmental and Life Sciences, Wroclaw (Poland)

    2013-12-01

    Two bicyclic lactones with gem-dimethylcyclohexane rings ({delta}-bromo-{gamma}-lactone and {delta}-iodo-{gamma}-lactone) were used as substrates for biotransformation by whole cells of several fungal strains (five cepas Fusarium, Nigrospora oryzae, Syncephalastrum racemosum, Stemphylium botryosum, Cunninghamella japonica and Acremonium sp). Some of the selected microorganisms (mainly Fusarium strains) transformed these lactones by hydrolytic dehalogenation into cis-(-)-2-hydroxy-4,4-dimethyl-9-oxabicyclo[4.3.0]nonan-8-one. The conversion of the substrate was equal or close to 100%, showing that this method allows for the complete removal of the halogen atom from the molecule, replacing it by a hydroxy group. The structures of all substrates and products were established on the basis of their spectral data. Hydroxylactone obtained as http://jbcs.sbq.org.br/audiencia{sub p}df.asp?aid2=3794&nomeArquivo=v24n12a05.pdf a result of biotransformation was examined for its biological activity against bacteria, yeasts and fungi. This compound inhibits the growth of some tested microorganisms. (author)

  2. Emissions from Petrol Engine Fueled Gasoline–Ethanol–Methanol (GEM Ternary mixture as Alternative Fuel

    Directory of Open Access Journals (Sweden)

    Thangavelu Saravana Kannan

    2015-01-01

    Full Text Available The increasing demands of petroleum fuels due to the rapid development automotive society coupled with the environmental pollution issues have inspired the efforts on exploring alternative fuels for internal combustion engines. Bioethanol obtained from biomass and bioenergy crops has been proclaimed as one of the feasible alternative to gasoline. In this study, the effect of gasoline–ethanol–methanol (GEM ternary blend on the emission characteristics of petrol engine was studied. Three different fuel blends, namely, E0 (gasoline, G75E21M4 (75% gasoline, 21% hydrous ethanol and 4% methanol and E25 (25% anhydrous ethanol and 75% gasoline were tested in a 1.3-l K3-VE spark-ignition engine. The results indicate that, when G75E21M4 fuel blend was used, a significant drop in CO, CO2, NOx and HC emissions by about 42%, 15%, 7% and 5.2% compared to E0, respectively. Moreover, the emission results for G75E21M4 are marginally lower than E25 whereas; HC emission was slightly higher than E25.

  3. Preparation and properties of gem-dichlorocyclopropane derivatives of long-chain fatty esters.

    Science.gov (United States)

    Jie, M S; Wong, C F

    1992-01-01

    Methyl oleate (18:1) and linoleate (18:2) were readily transformed to the corresponding gem-dichlorocyclopropane derivatives in high yield, using triethylbenzylammonium chloride as the phase-transfer catalyst in the presence of aqueous NaOH and CHCl3. Reaction of dichlorocarbene with methyl 12-hydroxystearate furnished methyl 12-chlorostearate (49%) and 12-O-formylstearate (19%). The hydroxy group in methyl ricinoleate was protected (O-tetrahydropyran-2'-yl) prior to dichlorocyclopropanation of the ethylenic bond. Removal of the protecting group allowed the hydroxy group to be converted to a chloride, O-acetyl, azido or O-formyl function. Treatment of methyl ricinoleate with thionyl chloride, followed by the reaction with dichlorocarbene gave the corresponding 12-chloro-dichlorocyclopropane derivative. The dichlorocyclopropane derivative of oleic acid was transformed to a C19 allenic fatty acid when treated with t-butyl lithium. However, the remaining dichlorocyclopropane derivatives containing an additional functional group in the alkyl chain, failed to yield the corresponding allenic derivatives. All derivatives were characterized by a combination of spectroscopic and chromatographic techniques, including infrared, 1H nuclear magnetic resonance (NMR), and 13C NMR spectroscopy.

  4. Raman microspectrometry, FT-IR and inclusion characteristics of gem garnets from Tanzania and Madagascar

    Institute of Scientific and Technical Information of China (English)

    Sang-kon Kim; Maeng-eon Park; Seung-gyun Baek; Kyu-youl Sung; Sun-ok Kim; Hee-yul Park

    2004-01-01

    Chemical composition, Raman microspectrometry, and Fourier transform infrared (FT-IR) and SEM-CL (Cathodluminescence) analyses are carried out for Tanzania and Madagascar garnets for locality identification. Inclusion study was sustained after electron probe microanalysis (EPMA). Needle-like illmenites, apatites and zircons were the most common solid inclusions in Tanzania garnets. Madagascar garnets revealed rutile needles and apatites were also observed, but differences in size, shape and distribution patterns were noticed compared to Tanzania garnets. Tanzania garnets exhibited all types of observable fluid inclusions such as "fingerprint" pattern, called Type Ⅰ-A, liquid-only (L) single phase fluid inclusion, called Type Ⅰ-B and Type Ⅱ-A (L + S), Type Ⅱ-B (L + V) and Type Ⅲ-A (L + Sylvite +S), Type Ⅲ-B (L+S+V), while no more than two phase fluid inclusions found in both Madagascar and Korea garnets even if all examined garnets from three localities retained "fingerprint" features, so called, partially healed fractures, in common. Chemical composition, Raman microspectrometry and Fourier transform infrared (FT-IR) analysis taken turned out to be useful methods for the purpose of this study. Using consequences of SEM-CL and inclusion study, accordingly,the locality identification of gem-quality garnets is capable of being available in further application for other kinds of gemstones.

  5. Automation technology with future perspectives. Natural gas underground storage with ABB Advant {sup trademark} OCS; Automatisierungswelt mit Zukunft. Untertageerdgasspeicherung mit ABB-Advant {sup trademark} OCS

    Energy Technology Data Exchange (ETDEWEB)

    Kerscht, S.M. [SK Automation AG, Basel (Switzerland); Katzenbach, B. [VEW Energie AG, Dortmund (Germany). Abt. Leittechnik

    1996-09-13

    The natural gas underground storage Kalle, operated by the Vereinigte Elektrizitaetswerke at Dortmund is used for the reduction of natural gas peaks. The installed control plant (PSI) consists of UNIX-work stations and server (DEC alpha series) with a modular control system. Thus the preconditions have been established in order to observe and if necessary control all VEW storage from Dortmund by means of peer-to-peer connections based on TCP/IP. In comparison to classic remote control systems, peer-to-peer connections are more flexible, more efficient and cost-effective because standard hardware can be applied. (MSK) [Deutsch] Der Untertageerdgasspeicher Kalle, der von den Vereinigten Elektrizitaetswerken mit Sitz in Dortmund betrieben wird, dient zur Reduzierung von Erdgasspitzen. Die dort installierten Leitanlage (PSI) besteht aus UNIX-Workstations und -Servern (DEC-alpha-Serie) mit einem modularen Leitsystemaufsatz. Damit sind die Voraussetzungen geschaffen, um mit Hilfe von Rechner-Rechner-Kopplungen auf Basis TCP/IP von Dortmund aus alle VEW-Speicher zu beobachten und bei Bedarf auch zu steuern. Die Rechner-Rechner-Kopplungen sind gegenueber klassischen Fernwirkstrecken wesentlich flexibler, leistungsfaehiger und letztlich auch preiswerter, da Standardhardware verwendet werden kann. (MSK)

  6. Value of radiotherapy in treatment of humeroscapular periarthritis. Comparison with MRI findings; Strahlentherapie der Periarthritis humeroscapularis mit ultraharten Photonen. Vergleich mit kernspintomographischen Befunden

    Energy Technology Data Exchange (ETDEWEB)

    Zwicker, C. [Hegau Klinikum Singen (Germany). CT/MRT Abt.; Hering, M. [Hegau Klinikum Singen (Germany). Roentgenologisches Zentralinstitut; Brecht, J. [Hegau Klinikum Singen (Germany). Anaesthesiologisches Inst.; Bjoernsgaerd; Kuhne-Velte, H.J. [Klinikum Konstanz (Germany). Strahlentherapeutische Belegabt.; Kern, A. [Neurologische Praxis Singen (Germany)

    1998-09-01

    Purpose: Evaluation of MRI in radiotherapy of humeroscapular periarthritis. Patients and methods: Seventy-seven patients with humeroscapular periarthritis prospectively underwent MRI before radiotherapy. Results: Six months after radiotherapy, 34% of the patients had achieved complete pain relief, 35% major pain relief. Twenty percent had only slight improvement and 12% no improvement. Positive correlation of radiotherapy outcome and MRI findings could be shown for acute tendinitis, erosions, and complete and incomplete ruptures of the supraspinatus tendon. Conclusions: Radiotherapy is highly effective in the treatment of humeroscapular periarthritis. The indication can be improved using MRI. (orig.) [Deutsch] Fragestellung: Aussagefaehigkeit der MRT vor Strahlentherapie der Periarthritis humeroscapularis. Methodik: 77 Patienten mit Periarthritis humeroscapularis wurden prospektiv vor der Strahlentherapie mit einem Linearbeschleuniger MR-tomographisch untersucht. Ergebnisse: 6 Monate nach Beendigung der Radiatio waren 34% der Patienten beschwerdefrei. 35% zeigten eine wesentliche Besserung. 20% waren nur geringfuegig gebessert, waehrend bei 12% der Patienten die Symptomatik unveraendert fortbestand. Eine positive Korrelation der MR-Befunde mit dem Therapieerfolg bestand bei akuten Tendinitiden, Usuren sowie kompletten und inkompletten Rupturen der Supraspinatussehne. Schlussfolgerungen: Die Strahlentherapie ist neben operativen Verfahren eine weitere wertvolle Methode zur Behandlung der Periarthritis humeroscapularis. Die MRT ist zur Indikationstellung sinnvoll. (orig.)

  7. Der Bürocomputer in einem Informationsverbund : Erfahrungen mit einem computergestützten Büro-Informationssystem (COBIS)

    OpenAIRE

    Zimmermann, Harald H.

    1981-01-01

    Zimmermann beschreibt den Stand der Technik im Bereich der computergestützten Informations- und Kommunikationsprozesse im Büro (Büroautomatisierung) mit dem Schwerpunkt "Sprachverarbeitung mit dem Computer". Er geht auf das Projekt "COBIS - Labormodell eines textuellen Büro-Informations-Systems" ein und beschreibt die immer leichtere und verbesserte Integration von Kleincomputern in Informations- und Kommunikationsverbünde.

  8. The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins

    Energy Technology Data Exchange (ETDEWEB)

    Caillat, Christophe; Fish, Alexander [The Netherlands Cancer Institute, 1066 CX Amsterdam (Netherlands); Pefani, Dafni-Eleftheria; Taraviras, Stavros; Lygerou, Zoi [University of Patras, 26505 Rio, Patras (Greece); Perrakis, Anastassis, E-mail: a.perrakis@nki.nl [The Netherlands Cancer Institute, 1066 CX Amsterdam (Netherlands)

    2015-10-31

    The GemC1 coiled-coil structure has subtle differences compared with its homologues Geminin and Idas. Co-expression experiments in cells and biophysical stability analysis of the Geminin-family coiled coils suggest that the GemC1 coiled coil alone is unstable. GemC1, together with Idas and Geminin, an important regulator of DNA-replication licensing and differentiation decisions, constitute a superfamily sharing a homologous central coiled-coil domain. To better understand this family of proteins, the crystal structure of a GemC1 coiled-coil domain variant engineered for better solubility was determined to 2.2 Å resolution. GemC1 shows a less typical coiled coil compared with the Geminin homodimer and the Geminin–Idas heterodimer structures. It is also shown that both in vitro and in cells GemC1 interacts with Geminin through its coiled-coil domain, forming a heterodimer that is more stable that the GemC1 homodimer. Comparative analysis of the thermal stability of all of the possible superfamily complexes, using circular dichroism to follow the unfolding of the entire helix of the coiled coil, or intrinsic tryptophan fluorescence of a unique conserved N-terminal tryptophan, shows that the unfolding of the coiled coil is likely to take place from the C-terminus towards the N-terminus. It is also shown that homodimers show a single-state unfolding, while heterodimers show a two-state unfolding, suggesting that the dimer first falls apart and the helices then unfold according to the stability of each protein. The findings argue that Geminin-family members form homodimers and heterodimers between them, and this ability is likely to be important for modulating their function in cycling and differentiating cells.

  9. Pack also the sauna. Integration of electricity storage; Auch die Sauna mit rein. Einbindung von Stromspeichern

    Energy Technology Data Exchange (ETDEWEB)

    Ullrich, Sven

    2013-10-01

    The installers have to handle with a variety of variables and options to plan and integrate the correct personal use system of solar power systems for their customers. [German] Die Installateure muessen mit einer Vielzahl von Variablen und Varianten zurechtkommen, um das richtige Eigenverbrauchssystem einer Solarstromanlage fuer ihre Kunden zu planen und einzubauen.

  10. eLearning in der Volksschule – ein Mehrwert? - Aspekte zu einem zukunftsorientierten Unterricht mit IKT

    Directory of Open Access Journals (Sweden)

    Ursula Dopplinger

    2011-09-01

    Full Text Available In einer Panelstudie wurde die Verbesserung der Schlüsselkompetenzen von Schülerinnen und Schülern durch eLearning in vier Volksschulen untersucht. Mit der verwendeten Webquest-Methode wurden bei drei von vier Untersuchten im Bereich der Schlüsselkompetenzen Erfolge erzielt.

  11. How Much Have They Retained? Making Unseen Concepts Seen in a Freshman Electromagnetism Course at MIT

    Science.gov (United States)

    Dori, Yehudit Judy; Hult, Erin; Breslow, Lori; Belcher, John W.

    2007-01-01

    The introductory freshmen electromagnetism course at MIT has been taught since 2000 using a studio physics format entitled TEAL--Technology Enabled Active Learning. TEAL has created a collaborative, hands-on environment where students carry out desktop experiments, submit web-based assignments, and have access to a host of visualizations and…

  12. Underground storage with floating cover. An overview; Erdbeckenspeicher mit schwimmender Abdeckung. Eine Uebersicht

    Energy Technology Data Exchange (ETDEWEB)

    Heller, A.; Maureschat, G.; Duer, K. [Technical Univ. of Denmark, Lyngby (Denmark). Dept. of Buildings and Energy

    1998-12-31

    A number of underground stores have been developed in recent years in Denmark. The development has been subsidised with funds of `Development program renewable energy` launched by the Danish Ministry for Environment and Energy. First experience reports on underground storage show that more emphasis must be put on the development of storage sealing and cover construction. Hence research works currently focuses on the investigation of liner material and further development of floating cover constructions. The target is the development of underground storage using solar energy for heating that can compete with conventional heating systems technically and economically. (orig.) [Deutsch] In Daenemark hat man in den letzten Jahren eine Reihe von Erdbeckenspeichern entwickelt. Die Entwicklung wird mit Mitteln aus dem `Entwicklungsprogramm Erneuerbare Energie` vom daenischen Umwelt- und Energieministerium finanziell gefoerdert. Die ersten Erfahrungen mit Erdbeckenspeichern haben gezeigt, dass ein verstaerkter Einsatz bei der Entwicklung von Abdichtungen des Speichers und von Deckelkonstruktionen gefordert ist. Deshalb wird in Daenemark aktuell mit der Untersuchung von Linermaterialien und der Weiterentwicklung von schwimmenden Deckelkonstruktionen gearbeitet. Das Ziel dieser Arbeit ist es, Erdbeckenspeicher zu entwickeln, die die Ausnutzung von Sonnenenergie zur Waermeversorgung im Vergleich mit herkoemmlicher Waermeversorgung sowohl technisch als auch oekonomisch konkurrenzfaehig macht. (orig.)

  13. Die frontotemporale Lobärdegeneration: Ein Syndrom mit variabler klinischer Manifestation

    Directory of Open Access Journals (Sweden)

    Jesse S

    2012-01-01

    Full Text Available Die frontotemporalen Lobärdegenerationen (FTD als dritthäufigste degenerative Demenzform nach der Alzheimer-Demenz und der Lewy-Body-Demenz lassen sich anhand ihres klinischen Profils in 3 Varianten einteilen: (1 Die frontale Verlaufsform (bvFTD mit im Vordergrund stehender Änderung der Persönlichkeit und des Sozialverhaltens, (2 die semantische Demenz (SD mit vornehmlich bitemporaler kortikaler Atrophie und korrespondierend defizitärem Wissen über Wortbedeutungen, allgemeines Faktenwissen sowie einer visuell-gnostischen Störung und (3 die progressive nicht-flüssige Aphasie (PNFA mit einer meist nicht-flüssigen Aphasie und frontal-operkulär betonter zerebraler Atrophie. Die genannten klinischen Symptomatiken der FTD lassen sich mit den üblichen neuropsychologischen Testverfahren zur Erfassung demenzieller Syndrome anfangs nur sehr schwer diagnostizieren, sodass hier quantifizierbare Verhaltens- und Sprachtests eine bessere Diagnosestellung erlauben. Therapeutisch steht die Psychoedukation Angehöriger sowie in die Pflege involvierter Personen im Vordergrund, eine medikamentöse Therapie beschränkt sich auf symptomatische Maßnahmen.

  14. Biogas - a new energy source saves fossil resources; Biogas - mit neuer Energie Ressourcen schonen

    Energy Technology Data Exchange (ETDEWEB)

    Thoss, C. (comp.)

    2001-07-01

    The new German Renewable Energy Sources Act (EEG) of 2000 made conditions for biogas more favourable - small wonder, as the German Biogas Association (Fachverband Biogas e.V.) co-operated with written expert opinions and many discussions with decision-makers. The subjects discussed at the 10th Biogas Conference reflect the current situation and will provide a basis for committee work in 2001. [German] Im Jahr 2000 haben sich die gesetzlichen Rahmenbedingungen fuer den Biogasbereich mit dem Inkrafttreten des erneuerbaren Energiegesetz (EEG) sehr positiv entwickelt. Der Fachverband Biogas e.V. hat mit schriftlichen Stellungnahmen und in vielen Gespraechen mit Entscheidungstraegern diese Bedingungen mitgestaltet. In Zukunft gibt es noch viele Aufgaben fuer eine effektive Interessenvertretung der Biogasbranche auf Laender- und Bundesebene. Die Themen, die auf der 10. Biogastagung diskutiert werden, spiegeln die Fragen wieder, die unter Experten derzeit intensiv diskutiert werden. Die Ergebnisse des Erfahrungsaustausches auf dieser Tagung werden die Grundlage fuer die Arbeit der Gremien im Fachverband Biogas im Jahr 2001 sein. Mit dem vorliegenden Tagungsband ist es gelungen, die Basis fuer die fachlichen Gespraeche waehrend und nach der Tagung schaffen. (orig.)

  15. Partizipatives Lernen mit dem Social Web gestalten. Zum Widerspruch einer verordneten Partizipation

    Directory of Open Access Journals (Sweden)

    Kerstin Mayrberger

    2012-01-01

    Full Text Available Dieser Beitrag geht von der Annahme aus, dass das Social Web Potenziale für ein partizipatives Lernen mit sich bringt. Zugleich setzt er sich mit der damit einhergehenden Problematik auseinander, dass mit dem Einsatz von Social Software ein tatsächliches partizipatives Lernen, das auf Freiwilligkeit basiert, in formalen Lehr- und Lernprozessen systembedingt nur begrenzt realisiert werden kann. Partizipation in formalen Bildungskontexten kann insofern immer nur eine von den Lehrpersonen bei der Gestaltung von Lernumgebungen bewusst ermöglichte und somit letztlich eine Form «verordneter Partizipation» sein. Dieser (medien-pädagogische Widerspruch kann in institutionellen Bildungskontexten wie der Schule nie vollständig gelöst werden, wohl aber können adäquate Handlungsoptionen entwickelt werden. In diesem Sinne stellt der Beitrag ein Stufenmodell vor, das einen differenzierten Umgang mit den Grenzen und Möglichkeiten von Social Software beim Lehren und Lernen erlaubt. Es kann Lehrende bei der Planung und Analyse von (vermeintlich partizipativen Lehr- und Lernprozessen darin unterstützen, die mediendidaktischen Bedingungen für eine (Nicht-Partizipation klarer zu bestimmen und entsprechende Massnahmen zu ergreifen.

  16. Status of High Intensity Polarized Electron Gun at Mit-Bates

    Science.gov (United States)

    Tsentalovich, E.; Bessuille, J.; Tiunov, M.

    2011-01-01

    MIT-Bates, in collaboration with BNL, has developed a high intensity polarized electron gun for the eRHIC project. The gun implements large area cathode, ring-shaped beam and active cathode cooling. The paper describes the current status of the project.

  17. Verarbeitung negativer Rückmeldung mit unterschiedlich affektiver Wertigkeit bei Kindern : eine fMRT-Studie

    OpenAIRE

    Pelz, Sabrina

    2009-01-01

    Verarbeitung von negativem Feedback (Rückmeldung) mit unterschiedlich affektiver (emotionaler) Wertigkeit bei Kindern (10 bis 13 Jahre alt). FMRT-Studie und neuronale Korrelate. Paradigma: Pseudo-Chemie-Aufgabe. Feedback: zweiteilig; individuelles Feedback und verzögert Feedback einer Peergroup. Kontraste: negatives Feedback > positivem Feedback, hoch affektives negatives Feedback > niedrig affektives negatives Feedback und niedrig affektives negatives Feedback > hoch affektives nega...

  18. Schwerpunktseminar : "Dazugehören? Umgang mit Minderheiten" / Liliāna Vancāne

    Index Scriptorium Estoniae

    Vancāne, Liliāna

    2016-01-01

    17. -20. märtsini 2016 Tartus toimunud seminarist "Dazugehören? Umgang mit Minderheiten. Estland und Lettland gestern-heutu-morgen". Seminarist sotsiaalse kuuluvuse ja vähemuste teemal. Suurepäraselt korraldatud ürituse parim osa oli töötuba

  19. Freies ZIMmer. Technologie- und Lernkulturen im "Zentrum für Interaktion mit Digitalen Medien" (ZIM

    Directory of Open Access Journals (Sweden)

    Hendrik Bunke

    2005-06-01

    Full Text Available Das ZIM an der Universität Bremen ist eine Lern- und Forschungswerkstatt für Digitale Medien in der Bildung. Der Beitrag erläutert Idee und Konzept des ZIM, schildert die Kooperation mit einer Schule im Projekt «ZIM@School» und skizziert als kurzen Ausblick methodische und inhaltliche Fragen der Evaluierung.

  20. Dezentrale selbstorganisierte Grobplanung von Intralogistiksystemen mit Hilfe eines Software-Agentensystems

    OpenAIRE

    Yousefifar, Ramin; Wehking, Karl-Heinz; Beyer, Theresa; Jazdi, Nasser; Göhner, Peter

    2014-01-01

    In diesem Beitrag wird eine dezentral aufgebaute und auf Selbstorganisation basierende Methodik zur Grobplanung von Intralogistiksystemen thematisiert. Diese Methodik sieht eine Kombination des Wissenschaftsgebiets der Agentensysteme aus der Informatik mit der Materialflussplanung vor. Dieser Artikel leistet somit einen Beitrag für die Entwicklung eines intelligenten, rechnergestützten Assistenzsystems zur Planung intralogistischer Systeme. This article introduces a decentralized and self-...

  1. Erfahrung mit der Extraktion von transvenösen Kardioverter-Defibrillator (ICD Sonden

    Directory of Open Access Journals (Sweden)

    Dörnberger V

    1999-01-01

    Full Text Available Die ICD-Therapie ist ein bewährtes Verfahren zur Behandlung lebensbedrohlicher ventrikulärer Herzrhythmusstörungen. Defekte der komplex aufgebauten transvenösen Sondensysteme sind beschrieben. Meist ist eine komplette Entfernung defekter Sonden sinnvoll. Wir berichten über unsere Erfahrung mit der Entfernung von 13 transvenösen Elektrodensystemen. In 7 Fällen handelt es sich um eine Endotak C 0072 Sonde (CPI/Guidant und in 6 Fällen um eine Medtronic Transvene 6936 Elektrode. Das Sondenalter zum Zeitpunkt der Extraktion lag zwischen 1,5 und 77,6 Monaten (Mittelwert 36,3 ± 18. Als Extraktionshilfen wurden das VascoExtor Stylet S (Vascomed in 6 Fällen und das Byrd Locking-Stylet 0.017 (0.018 inches (Cook in 4 Fällen verwendet. Alle Extraktionen erfolgten unter transösophagealem Echokardiographie-Monitoring (TEE und Herz-Lungenmaschinen-Bereitschaft (HLM. Ohne Dilatations-Sheath war eine Extraktion nur innerhalb der ersten 3 Monate nach Implantation möglich (n = 3. Ein besonderes Problem stellt der im Vergleich zum Sondenkörper größere Durchmesser der Schockwendel dar, da die Sonde im Verlauf von einem Bindegewebsmantel fest umschlossen und mit der Venenwand verwachsen ist. Mit dem Byrd Dilatator-Schleusenset 10,0 Fr, 11,5 Fr und 13,0 Fr war in allen Fällen eine Lösung von der Venenwand möglich. Eine Extraktion einer Sonde (Medtronic Transvene war nach auswärtigen Vorversuchen mit Zerstörung der inneren Wendel nicht mehr möglich. In einem weiteren Fall konnten zwar die venösen Wandadhäsionen gelöst werden, die distale Schockwendel war jedoch in voller Länge mit dem Endokard verwachsen und konnte nur in einer offenen Herzoperation entfernt werden. In keinem Fall kam es zu einem bedeutsamen Perikarderguß. Kein Patient verstarb in Folge der Sondenextraktion. Zusammenfassend ist die Extraktion von ICD Sonden auch lange nach Implantation möglich. Trotz unserer relativ guten Erfahrung mit der Extraktion von ICD Sonden sollte

  2. Generation of nitryl chloride from chlorotrimethylsilane-acetyl nitrate reaction: A one-pot preparation of gem-chloronitro compounds from oximes

    Indian Academy of Sciences (India)

    Abdulkarim H A Mohammed; Gopalpur Nagendrappa

    2010-07-01

    While iso-amyl nitrite reacts with chlorotrimethylsilane to give NOCl, iso-amyl nitrate does not yield NO2Cl with silicon reagent. However, acetyl nitrate reacts successfully with chlorotrimethylsilane to give nitryl chloride, which is characterized by its UV spectrum. If it is generated in presence of ketoximes, gem-chloronitro as well as gem-chloronitroso compounds are formed in almost equal amounts, which together account for up to 80% yield. This is possibly the simplest one-pot reaction for the preparation of gem-chloronitro compounds which find several synthetic applications. If NO2Cl is generated in presence of cycloalkenes, the corresponding 1,2-dichlorocycloalkanes are obtained. Considering the evidence in hand, it is proposed that NO2Cl, initially formed by chlorotrimethylsilane-acetyl nitrate reaction, decomposes to Cl2, and N2O4. Then chlorine reacts with oximes to produce first gem-chloronitroso compounds, which are oxidized by NO2Cl or N2O4 to gem-chloronitro compounds, and with cycloalkenes it gives dichlorocycloalkanes.

  3. A Growth Evaluation and Analysis of Companies Listed on GEM%我国创业板上市公司成长性评价分析

    Institute of Scientific and Technical Information of China (English)

    阮青松; 常乐

    2012-01-01

    Scientific evaluation of GEM listing companies' growth is an important precondition for the healthy development of China's GEM. Taking 183 companies listed on China's GEM as a sample, this article constructs a system of growth-evaluating indexes for GEM listing companies by theoretical analysis and makes an empirical research using factor analysis model. The results show that company' s capacity of risk-controlling, profitability, growth rate, operational efficiency and capacity of innovating mainly reflect the growth of companies listed on GEM.%科学地评价创业板上市公司的成长性是我国创业板市场健康发展的重要前提,通过理论分析构建了创业板上市公司成长性评价指标体系,并以在我国创业板上市的183家公司为样本,采用因子分析模型进行实证分析.研究结果表明:公司的风险控制能力、盈利能力、成长速度、经营效率和创新能力是创业板上市公司成长性的主要体现.

  4. Studies of aging and HV break down problems during development and operation of MSGC and GEM detectors for the Inner Tracking System of HERA-B

    CERN Document Server

    Bagaturia, Yu S; Dreis, H B; Eisele, Franz; Gorbunov, I V; Gradl, S; Gradl, W; Hausmann, S A; Hildebrandt, M; Hott, T; Keller, S; Krauss, C; Lomonosov, B N; Negodaev, M A; Richter, C; Robmann, P; Schmidt, B; Straumann, U; Truöl, P; Visbeck, S; Walter, T; Werner, C; Werthenbach, U; Zech, G; Zeuner, T; Ziegler, M

    2002-01-01

    The results of five years of development of the inner tracking system of the HERA-B experiment and first experience from the data taking period of the year 2000 are reported. The system contains 184 chambers, covering a sensitive area of about 20 * 20 cm2 each. The detector is based on microstrip gas counters (MSGCs) with diamond like coated (DLC) glass wafers and gas electron multipliers (GEMs). The main problems in the development phase were gas discharges in intense hadron beams and aging in a high radiation dose environment. The observation of gas discharges which damage the electrode structure of the MSGC led to the addition of the GEM as a first amplification step. Spurious sparking at the GEM cannot be avoided completely. It does not affect the GEM itself but can produce secondary damage of the MSGC if the electric field between the GEM and the MSGC is above a threshold depending on operation conditions. We observed that aging does not only depend on the dose but also on the spot size of the irradiated...

  5. Gasoline, Ethanol and Methanol (GEM Ternary Blends utilization as an Alternative to Conventional Iraqi Gasoline to Suppress Emitted Sulfur and Lead Components to Environment

    Directory of Open Access Journals (Sweden)

    Miqdam Tariq Chaichan

    2016-09-01

    Full Text Available Iraqi conventional gasoline characterized by its low octane number not exceed 82 and high lead and sulfur content. In this paper tri-component or ternary, blends of gasoline, ethanol, and methanol presented as an alternative fuel for Iraqi conventional gasoline. The study conducted by using GEM blend that equals E85 blend in octane rating. The used GEM selected from Turner, 2010 collection. G37 E20 M43 (37% gasoline + 20% ethanol+ 43% methanol was chosen as GEM in present study. This blend used in multi-cylinder Mercedes engine, and the engine performance, and emitted emissions compared with that produced by a gasoline engine. The results show that this blend can formulate with available Iraqi produced materials. GEM ternary blend offers significant advantages in terms of engine performance compared to gasoline. Also, GEM higher useful compression ratio (HUCR = 9.25 while gasoline HUCR=7.5. The increment in engine bp was 24.12%, BSFC reduced by 13.9% and brake thermal efficiency increased by 19.59%. The volumetric efficiency increased by 8.06%. Also, CO, HC concentrations were reduced by 30.5%, 25.16% respectively. Smoke opacity reduced by 46.49% and CO2 concentrations reduced by 5% as well as NOx concentrations that reduced by 1.75%.

  6. Kontrazeption und Schwangerschaft bei Frauen mit Epilepsie - Eine Stellungnahme der DGGEF

    Directory of Open Access Journals (Sweden)

    Rabe T

    2010-01-01

    Full Text Available Epilepsien gehören zu den häufigsten neurologischen Erkrankungen. Für Frauen, die unter einer Epilepsie leiden, ist eine enge Zusammenarbeit zwischen dem betreuenden Neurologen und Gynäkologen unerlässlich, da sowohl die Epilepsie an sich aber auch die antiepileptische Medikation viele Bereiche des Lebens der betroffenen Frauen negativ beeinflussen kann: so können Fertilität und reproduktive Funktionen eingeschränkt sein, aber auch die bidirektionalen Interaktionen zwischen der antiepileptischen Therapie und hormonalen Kontrazeptiva müssen berücksichtigt werden, um ungeplante Schwangerschaften und eine Verschlechterung der Anfallskontrolle zu verhindern. Das mit einer antiepileptischen Therapie assoziierte teratogene Risiko muss, ebenso wie das mit der Behandlung möglicherweise verbundene Risiko einer ungünstigen Beeinflussung der kognitiven Entwicklung beim Kind, gegenüber dem Nutzen einer optimalen Anfallskontrolle abgewogen werden. Wenn möglich, sollten Frauen im reproduktionsfähigen Alter auf ein wenig teratogenes Therapieregime eingestellt werden. Eine umfassende proaktive präkonzeptionelle Beratung ist bei Frauen mit Epilepsie obligat, um bei Mutter und Kind einen möglichst unproblematischen Verlauf von Schwangerschaft, Geburt und Postpartalzeit zu ermöglichen. Im Allgemeinen wird bei Frauen mit Epilepsie eine hochdosierte, bereits präkonzeptionell zu beginnende Folsäureprophylaxe angeraten, um das Risiko für das Auftreten großer Fehlbildungen zu reduzieren. Im Verlauf der Schwangerschaft können je nach antiepileptischer Therapie eine regelmäßige Überprüfung der Antieepileptikaspiegel und ggf. auch eine Anpassung der Dosierung notwendig werden. Eine differenzierte Fehlbildungsdiagnostik sollte genauso wie die regelmäßige Überwachung der Schwangerschaft auf geburtshilfliche Komplikationen Teil der Routineversorgung von Frauen mit Epilepsie sein.

  7. Hydraulic analysis of water supply networks and controlling the leak using WATER GEMS model

    Directory of Open Access Journals (Sweden)

    Mahmood Motevalizadeh

    2016-03-01

    Full Text Available Given that the discussion on water is strategic in terms of economic and social aspects as well as environmental impact, water leak in urban water-supply systems is very important, so, dealing with it is necessary and inevitable. Controlling and reducing water leak are of the main goals of water supplier organization due to limitations in terms of water resources, especially in dry lands which have few water resources. Pressure management is an efficient tool to reduce costs, enhance the operation of the network and therefore, it reduces the leak and increases the life of facilities and equipment and reduces the number of accidents. Smart pressure containment is a good way to prevent excess pressure in network to control undesirable phenomenon of leak which is directly related to pressure. In this study, Badamuiyeh water supply complex in Kerman City was selected to study on adjusting the pressure to control the leak of water and the hydraulic analysis was performed with demand-based method (DDSM, which is common technique and demand is constant, by Water GEMS software. For this end, the pressure reducing valves (prv were installed in critical point and they were timed to provide standard pressure in all nodes of the network and then, the impact of smart pressure management on water supply system has been investigated. Then its impact on the leak was examined and the results show that smart pressure control through pressure-reducing valve is a proper method for optimal management of water and reducing the leak significantly that with 45.15% reduction in average pressure, one can reduce the leak as much as 25.67% that as its result, 15380 m3 of water is annually saved in this region which is equal to 27.18% of consuming water.

  8. J-GEM follow-up observations of the gravitational wave source GW151226*

    Science.gov (United States)

    Yoshida, Michitoshi; Utsumi, Yousuke; Tominaga, Nozomu; Morokuma, Tomoki; Tanaka, Masaomi; Asakura, Yuichiro; Matsubayashi, Kazuya; Ohta, Kouji; Abe, Fumio; Chimasu, Sho; Furusawa, Hisanori; Itoh, Ryosuke; Itoh, Yoichi; Kanda, Yuka; Kawabata, Koji S.; Kawabata, Miho; Koshida, Shintaro; Koshimoto, Naoki; Kuroda, Daisuke; Moritani, Yuki; Motohara, Kentaro; Murata, Katsuhiro L.; Nagayama, Takahiro; Nakaoka, Tatsuya; Nakata, Fumiaki; Nishioka, Tsubasa; Saito, Yoshihiko; Terai, Tsuyoshi; Tristram, Paul J.; Yanagisawa, Kenshi; Yasuda, Naoki; Doi, Mamoru; Fujisawa, Kenta; Kawachi, Akiko; Kawai, Nobuyuki; Tamura, Yoichi; Uemura, Makoto; Yatsu, Yoichi

    2017-02-01

    We report the results of optical-infrared follow-up observations of the gravitational wave (GW) event GW151226 detected by the Advanced LIGO in the framework of J-GEM (Japanese collaboration for Gravitational wave ElectroMagnetic follow-up). We performed wide-field optical imaging surveys with the Kiso Wide Field Camera (KWFC), Hyper Suprime-Cam (HSC), and MOA-cam3. The KWFC survey started at 2.26 d after the GW event and covered 778 deg2 centered at the high Galactic region of the skymap of GW151226. We started the HSC follow-up observations from ˜12 d after the event and covered an area of 63.5 deg2 of the highest probability region of the northern sky with limiting magnitudes of 24.6 and 23.8 for the i and z bands, respectively. MOA-cam3 covered 145 deg2 of the skymap with the MOA-red filter ˜2.5 mon after the GW alert. The total area covered by the wide-field surveys was 986.5 deg2. The integrated detection probability for the observed area was ˜29%. We also performed galaxy-targeted observations with six optical and near-infrared telescopes from 1.61 d after the event. A total of 238 nearby (≤100 Mpc) galaxies were observed with a typical I band limiting magnitude of ˜19.5. We detected 13 supernova candidates with the KWFC survey, and 60 extragalactic transients with the HSC survey. Two thirds of the HSC transients were likely supernovae and the remaining one third were possible active galactic nuclei. With our observational campaign, we found no transients that are likely to be associated with GW151226.

  9. Serial data acquisition for the X-ray plasma diagnostics with selected GEM detector structures

    Science.gov (United States)

    Czarski, T.; Chernyshova, M.; Pozniak, K. T.; Kasprowicz, G.; Zabolotny, W.; Kolasinski, P.; Krawczyk, R.; Wojenski, A.; Zienkiewicz, P.

    2015-10-01

    The measurement system based on GEM—Gas Electron Multiplier detector is developed for X-ray diagnostics of magnetic confinement tokamak plasmas. The paper is focused on the measurement subject and describes the fundamental data processing to obtain reliable characteristics (histograms) useful for physicists. The required data processing have two steps: 1—processing in the time domain, i.e. events selections for bunches of coinciding clusters, 2—processing in the planar space domain, i.e. cluster identification for the given detector structure. So, it is the software part of the project between the electronic hardware and physics applications. The whole project is original and it was developed by the paper authors. The previous version based on 1-D GEM detector was applied for the high-resolution X-ray crystal spectrometer KX1 in the JET tokamak. The current version considers 2-D detector structures for the new data acquisition system. The fast and accurate mode of data acquisition implemented in the hardware in real time can be applied for the dynamic plasma diagnostics. Several detector structures with single-pixel sensors and multi-pixel (directional) sensors are considered for two-dimensional X-ray imaging. Final data processing is presented by histograms for selected range of position, time interval and cluster charge values. Exemplary radiation source properties are measured by the basic cumulative characteristics: the cluster position distribution and cluster charge value distribution corresponding to the energy spectra. A shorter version of this contribution is due to be published in PoS at: 1st EPS conference on Plasma Diagnostics

  10. Thermal properties of gem-quality moganite-rich blue chalcedony

    Energy Technology Data Exchange (ETDEWEB)

    Hatipoglu, M. [Dokuz Eyluel University, IMYO, Izmir Multidisciplinary Vocational School, Gemmology and Jewellery Program, 35140 Buca-Izmir (Turkey); Tuncer, Y.; Kibar, R.; Cetin, A. [Celal Bayar University, Faculty of the Arts and Sciences, Department of Physics, 45100 Muradiye-Manisa (Turkey); Karali, T. [Ege University, Institute of Nuclear Sciences, 35100 Bornova-Izmir (Turkey); Can, N., E-mail: cannurdogan@yahoo.co [Celal Bayar University, Faculty of the Arts and Sciences, Department of Physics, 45100 Muradiye-Manisa (Turkey)

    2010-11-15

    In this study, thermal properties and thermal decompositions of dehydration behaviour of gem-quality translucent blue chalcedonies, without banding or crystalline centre structure, from the Saricakaya-Eskisehir region in Turkey were studied by means of X-ray diffraction (XRD), inductively coupled plasma-atomic emission spectrometry (ICP-AES), Fourier transform infrared (FT-IR), thermoluminescence (TL), and simultaneously two thermal analyses of (DTA/TGA) spectroscopy. X-ray diffraction patterns of the blue chalcedony indicate the presence of two important chalcedonic silica phases with overlapped peaks at 4.26, 3.34, 2.28, 2.13, 1.82, 1.54, 1.38, and 137 A. During heating from the room temperature to 300 deg. C, the thermoluminescence pattern of the blue chalcedony shows a characteristic peak at 210 deg. C. This peak may be due to unusually high traces of the impurities S, Th, Tl, U, and W. During heating from the room temperature to 1400 deg. C, the TGA pattern of the blue chalcedony indicates that the weight loss is due to the silanol water loss only, and that this loss occurs in a wide temperature range between about 170 and 954 deg. C. In addition, after making some corrections concerning the artefact mass gain, being due to the drift with buoyancy effect of the atmosphere in its TGA curve, the moganite-rich blue chalcedony shows a relatively lower mass loss of 0.202%. The DTA pattern of the blue chalcedony displays both endothermic and exothermic behaviours because of silica phase transformations. There are one distinctive sharp endotherm and three weaker endotherms at 806 deg. C. In addition, there is one distinctive sharp exotherm and one weaker exotherm at 1270 deg. C.

  11. Frequency and characteristics of familial melanoma in Spain: the FAM-GEM-1 Study.

    Directory of Open Access Journals (Sweden)

    Iván Márquez-Rodas

    Full Text Available Familial history of melanoma is a well-known risk factor for the disease, and 7% melanoma patients were reported to have a family history of melanoma. Data relating to the frequency and clinical and pathological characteristics of both familial and non-familial melanoma in Spain have been published, but these only include patients from specific areas of Spain and do not represent the data for the whole of Spain.An observational study conducted by the Spanish Group of Melanoma (GEM analyzed the family history of patients diagnosed with melanoma between 2011 and 2013 in the dermatology and oncology departments.In all, 1047 patients were analyzed, and 69 (6.6% fulfilled criteria for classical familial melanoma (two or more first-degree relatives diagnosed with melanoma. Taking into account other risk factors for familial melanoma, such as multiple melanoma, pancreatic cancer in the family or second-degree relatives with melanoma, the number of patients fulfilling the criteria increased to 165 (15.8%. Using a univariate analysis, we determined that a Breslow index of less than 1 mm, negative mitosis, multiple melanoma, and a history of sunburns in childhood were more frequent in familial melanoma patients, but a multivariate analysis revealed no differences in any pathological or clinical factor between the two groups.Similar to that observed in other countries, familial melanoma accounts for 6.6% of melanoma diagnoses in Spain. Although no differences in the multivariate analysis were found, some better prognosis factors, such as Breslow index, seem more frequent in familial melanoma, which reflect a better early detection marker and/or a different biological behavior.

  12. Space weather effects on radio propagation: study of the CEDAR, GEM and ISTP storm events

    Directory of Open Access Journals (Sweden)

    D. V. Blagoveshchensky

    2008-06-01

    Full Text Available The impact of 14 geomagnetic storms from a list of CEDAR, GEM and ISTP storms, that occurred during 1997–1999, on radio propagation conditions has been investigated. The propagation conditions were estimated through variations of the MOF and LOF (the maximum and lowest operation frequencies on three high-latitude HF radio paths in north-west Russia. Geophysical data of Dst, Bz, AE as well as some riometer data from Sodankyla observatory, Finland, were used for the analysis. It was shown that the storm impact on the ionosphere and radio propagation for each storm has an individual character. Nevertheless, there are common patterns in variation of the propagation parameters for all storms. Thus, the frequency range Δ=MOF−LOF increases several hours before a storm, then it narrows sharply during the storm, and expands again several hours after the end of the storm. This regular behaviour should be useful for the HF radio propagation predictions and frequency management at high latitudes. On the trans-auroral radio path, the time interval when the signal is lost through a storm (tdes depends on the local time. For the day-time storms an average value tdes is 6 h, but for night storms tdes is only 2 h. The ionization increase in the F2 layer before storm onset is 3.5 h during the day-time and 2.4 h at night. Mechanisms to explain the observed variations are discussed including some novel possibilities involving energy input through the cusp.

  13. Impact of urban parameterization on high resolution air quality forecast with the GEM – AQ model

    Directory of Open Access Journals (Sweden)

    J. Struzewska

    2012-11-01

    Full Text Available The aim of this study is to assess the impact of urban cover on high-resolution air quality forecast simulations with the GEM-AQ (Global Environmental Multiscale and Air Quality model. The impact of urban area on the ambient atmosphere is non-stationary, and short-term variability of meteorological conditions may result in significant changes of the observed intensity of urban heat island and pollutant concentrations. In this study we used the Town Energy Balance (TEB parameterization to represent urban effects on modelled meteorological and air quality parameters at the final nesting level with horizontal resolution of ~5 km over Southern Poland. Three one-day cases representing different meteorological conditions were selected and the model was run with and without the TEB parameterization. Three urban cover categories were used in the TEB parameterization: mid-high buildings, very low buildings and low density suburbs. Urban cover layers were constructed based on an area fraction of towns in a grid cell. To analyze the impact of urban parameterization on modelled meteorological and air quality parameters, anomalies in the lowest model layer for the air temperature, wind speed and pollutant concentrations were calculated. Anomalies of the specific humidity fields indicate that the use of the TEB parameterization leads to a systematic reduction of moisture content in the air. Comparison with temperature and wind speed measurements taken at urban background monitoring stations shows that application of urban parameterization improves model results. For primary pollutants the impact of urban areas is most significant in regions characterized with high emissions. In most cases the anomalies of NO2 and CO concentrations were negative. This reduction is most likely caused by an enhanced vertical mixing due to elevated surface temperature and modified vertical stability.

  14. Frequency and Characteristics of Familial Melanoma in Spain: The FAM-GEM-1 Study

    Science.gov (United States)

    Márquez-Rodas, Iván; Martín González, Manuel; Nagore, Eduardo; Gómez-Fernández, Cristina; Avilés-Izquierdo, Jose Antonio; Maldonado-Seral, Cayetana; Soriano, Virtudes; Majem-Tarruella, Margarita; Palomar, Virginia; Maseda, Rocio; Martín-Carnicero, Alfonso; Puertolas, Teresa; Godoy, Elena; Cerezuela, Pablo; Ochoa de Olza, Maria; Campos, Begoña; Perez-Ruiz, Elisabeth; Soria, Ainara; Gil-Arnaiz, Irene; Gonzalez-Cao, Maria; Galvez, Elisa; Arance, Ana; Belon, Joaquin; de la Cruz-Merino, Luis; Martín-Algarra, Salvador

    2015-01-01

    Introduction Familial history of melanoma is a well-known risk factor for the disease, and 7% melanoma patients were reported to have a family history of melanoma. Data relating to the frequency and clinical and pathological characteristics of both familial and non-familial melanoma in Spain have been published, but these only include patients from specific areas of Spain and do not represent the data for the whole of Spain. Patients and methods An observational study conducted by the Spanish Group of Melanoma (GEM) analyzed the family history of patients diagnosed with melanoma between 2011 and 2013 in the dermatology and oncology departments. Results In all, 1047 patients were analyzed, and 69 (6.6%) fulfilled criteria for classical familial melanoma (two or more first-degree relatives diagnosed with melanoma). Taking into account other risk factors for familial melanoma, such as multiple melanoma, pancreatic cancer in the family or second-degree relatives with melanoma, the number of patients fulfilling the criteria increased to 165 (15.8%). Using a univariate analysis, we determined that a Breslow index of less than 1 mm, negative mitosis, multiple melanoma, and a history of sunburns in childhood were more frequent in familial melanoma patients, but a multivariate analysis revealed no differences in any pathological or clinical factor between the two groups. Conclusions Similar to that observed in other countries, familial melanoma accounts for 6.6% of melanoma diagnoses in Spain. Although no differences in the multivariate analysis were found, some better prognosis factors, such as Breslow index, seem more frequent in familial melanoma, which reflect a better early detection marker and/or a different biological behavior. PMID:25874698

  15. Review and Prospect of the Project of Global Earthquake Model (GEM)%全球地震模型(GEM)研究进展综述及应用前景展望

    Institute of Scientific and Technical Information of China (English)

    李昌珑; 吴健; 徐伟进; 高孟潭

    2016-01-01

    本文综述了全球地震模型(GEM)组织的工作目标、主要职能、工具(OpenQuake软件)和研究成果,并对GEM今后的发展和应用趋势进行了展望.借鉴GEM和OpenQuake,可以进一步完善我国的地震危险性分析模型,提升大型活动断裂带附近大城市和重大工程设施地震危险性分析的科学性.

  16. Analysis of the state of the art in the GEM project on gender and entrepreneur ship, period 1999-2009; Analisis del estdo del arte en el proyecto GEM sobre genero y actividad emprendedora perio 1999-2009

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Escobedo, M. C.; Postigo Jimenez, M. V.; Hernandez Mogollon, R.

    2012-11-01

    This paper fundamental aims to analyse the situation and evolution of research on gender in creation of business that has used the Global Entrepreneur ship Monitor (GEM) data, since the inception of the project until the end of 2009. To do this, the authors carries out analysis methods biblio metric about research both nationally and internationally. The results of the study show the fundamental documents and their types, primary scientific articles, main journals of dissemination, authors, institutions and most productive countries as well as techniques of analysis and data sources used. (Author) 47 refs.

  17. Comparison of the HadGEM2 climate-chemistry model against in situ and SCIAMACHY atmospheric methane data

    Directory of Open Access Journals (Sweden)

    G. D. Hayman

    2014-12-01

    Full Text Available Wetlands are a major emission source of methane (CH4 globally. In this study, we evaluate wetland emission estimates derived using the UK community land surface model (JULES, the Joint UK Land Earth Simulator against atmospheric observations of methane, including, for the first time, total methane columns derived from the SCIAMACHY instrument on board the ENVISAT satellite. Two JULES wetland emission estimates are investigated: (a from an offline run driven with Climatic Research Unit–National Centers for Environmental Prediction (CRU-NCEP meteorological data and (b from the same offline run in which the modelled wetland fractions are replaced with those derived from the Global Inundation Extent from Multi-Satellites (GIEMS remote sensing product. The mean annual emission assumed for each inventory (181 Tg CH4 per annum over the period 1999–2007 is in line with other recently published estimates. There are regional differences as the unconstrained JULES inventory gives significantly higher emissions in the Amazon (by ~36 Tg CH4 yr−1 and lower emissions in other regions (by up to 10 Tg CH4 yr−1 compared to the JULES estimates constrained with the GIEMS product. Using the UK Hadley Centre's Earth System model with atmospheric chemistry (HadGEM2, we evaluate these JULES wetland emissions against atmospheric observations of methane. We obtain improved agreement with the surface concentration measurements, especially at high northern latitudes, compared to previous HadGEM2 runs using the wetland emission data set of Fung et al. (1991. Although the modelled monthly atmospheric methane columns reproduce the large-scale patterns in the SCIAMACHY observations, they are biased low by 50 part per billion by volume (ppb. Replacing the HadGEM2 modelled concentrations above 300 hPa with HALOE–ACE assimilated TOMCAT output results in a significantly better agreement with the SCIAMACHY observations. The use of the GIEMS product to constrain the JULES

  18. Comparison of the HadGEM2 climate-chemistry model against in-situ and SCIAMACHY atmospheric methane data

    Directory of Open Access Journals (Sweden)

    G. D. Hayman

    2014-05-01

    Full Text Available Wetlands are a major emission source of methane (CH4 globally. In this study, we have evaluated wetland emission estimates derived using the UK community land surface model (JULES, the Joint UK Land Earth Simulator against atmospheric observations of methane, including, for the first time, total methane columns derived from the SCIAMACHY instrument on board the ENVISAT satellite. Two JULES wetland emission estimates were investigated: (a from an offline run driven with CRU-NCEP meteorological data and (b from the same offline run in which the modelled wetland fractions were replaced with those derived from the Global Inundation Extent from Multi-Satellites (GIEMS remote sensing product. The mean annual emission assumed for each inventory (181 Tg CH4 per annum over the period 1999–2007 is in line with other recently-published estimates. There are regional differences as the unconstrained JULES inventory gave significantly higher emissions in the Amazon and lower emissions in other regions compared to the JULES estimates constrained with the GIEMS product. Using the UK Hadley Centre's Earth System model with atmospheric chemistry (HadGEM2, we have evaluated these JULES wetland emissions against atmospheric observations of methane. We obtained improved agreement with the surface concentration measurements, especially at northern high latitudes, compared to previous HadGEM2 runs using the wetland emission dataset of Fung (1991. Although the modelled monthly atmospheric methane columns reproduced the large–scale patterns in the SCIAMACHY observations, they were biased low by 50 part per billion by volume (ppb. Replacing the HadGEM2 modelled concentrations above 300 hPa with HALOE–ACE assimilated TOMCAT output resulted in a significantly better agreement with the SCIAMACHY observations. The use of the GIEMS product to constrain JULES-derived wetland fraction improved the description of the wetland emissions in JULES and gave a good description

  19. Comparison of the HadGEM2 climate-chemistry model against in situ and SCIAMACHY atmospheric methane data

    Science.gov (United States)

    Hayman, G. D.; O'Connor, F. M.; Dalvi, M.; Clark, D. B.; Gedney, N.; Huntingford, C.; Prigent, C.; Buchwitz, M.; Schneising, O.; Burrows, J. P.; Wilson, C.; Richards, N.; Chipperfield, M.

    2014-12-01

    Wetlands are a major emission source of methane (CH4) globally. In this study, we evaluate wetland emission estimates derived using the UK community land surface model (JULES, the Joint UK Land Earth Simulator) against atmospheric observations of methane, including, for the first time, total methane columns derived from the SCIAMACHY instrument on board the ENVISAT satellite. Two JULES wetland emission estimates are investigated: (a) from an offline run driven with Climatic Research Unit-National Centers for Environmental Prediction (CRU-NCEP) meteorological data and (b) from the same offline run in which the modelled wetland fractions are replaced with those derived from the Global Inundation Extent from Multi-Satellites (GIEMS) remote sensing product. The mean annual emission assumed for each inventory (181 Tg CH4 per annum over the period 1999-2007) is in line with other recently published estimates. There are regional differences as the unconstrained JULES inventory gives significantly higher emissions in the Amazon (by ~36 Tg CH4 yr-1) and lower emissions in other regions (by up to 10 Tg CH4 yr-1) compared to the JULES estimates constrained with the GIEMS product. Using the UK Hadley Centre's Earth System model with atmospheric chemistry (HadGEM2), we evaluate these JULES wetland emissions against atmospheric observations of methane. We obtain improved agreement with the surface concentration measurements, especially at high northern latitudes, compared to previous HadGEM2 runs using the wetland emission data set of Fung et al. (1991). Although the modelled monthly atmospheric methane columns reproduce the large-scale patterns in the SCIAMACHY observations, they are biased low by 50 part per billion by volume (ppb). Replacing the HadGEM2 modelled concentrations above 300 hPa with HALOE-ACE assimilated TOMCAT output results in a significantly better agreement with the SCIAMACHY observations. The use of the GIEMS product to constrain the JULES-derived wetland

  20. Photometric Properties for Selected Algol-type Binaries. VIII. The Triple Systems DI Peg and AF Gem Revisited

    Science.gov (United States)

    Yang, Yuan-Gui; Yang, Ying; Li, Shu-Zheng

    2014-06-01

    New extensive photometry for two triple binary stars, DI Peg and AF Gem, was performed from 2012 October to 2013 January, with two small telescopes at Xinglong station (XLs) of NAOC. From new multi-color observations and previously published ones in literature, the photometric models were (re)deduced using the updated Wilson-Devinney code. The results indicated that the low third lights exist in two classic Algol-type binaries, whose fill-out factors for the more massive components are fp = 78.2(± 0.4)% for DI Peg, and fp = 69.0(± 0.3)% for AF Gem, respectively. Through analyzing the O-C curves, the orbital periods for two binaries change in the complicated mode. The period of DI Peg possibly appears to show two light-time orbits, whose modulated periods are P 3 = 54.6(± 0.5) yr and P 4 = 23.0(± 0.6) yr, respectively. The inferred minimum masses for the inner and outer sub-stellar companions are M in = 0.095 M ⊙ and M out = 0.170 M ⊙, respectively. Therefore, DI Peg may be a quadruple star. The orbital period of AF Gem appears to show a continuous period decrease or a cyclic variation; the latter may be preferable. The cyclic oscillation, with a period of 120.3(± 2.5) yr, may be attributed to the light-time effect due to the third body. This kind of additional companion may extract angular momentum from the central system, which may play a key role in the evolution of the binary.

  1. Optimization of the matrix inversion tomosynthesis (MITS) impulse response and modulation transfer function characteristics for chest imaging.

    Science.gov (United States)

    Godfrey, Devon J; McAdams, H P; Dobbins, James T

    2006-03-01

    Matrix inversion tomosynthesis (MITS) uses linear systems theory, along with a priori knowledge of the imaging geometry, to deterministically distinguish between true structure and overlying tomographic blur in a set of conventional tomosynthesis planes. In this paper we examine the effect of total scan angle (ANG), number of input projections (N), and plane separation/number of reconstructed planes (NP) on the MITS impulse response (IR) and modulation transfer function (MTF), with the purpose of optimizing MITS imaging of the chest. MITS IR and MTF data were generated by simulating the imaging of a very thin wire, using various combinations of ANG, N, and NP. Actual tomosynthesis data of an anthropomorphic chest phantom were acquired with a prototype experimental system, using the same imaging parameter combinations as those in the simulations. Thoracic projection data from two human subjects were collected for corroboration of the system response analysis in vivo. Results suggest that ANG=20 degrees, N=71, NP=69 is the optimal combination for MITS chest imaging given the inherent constraints of our prototype system. MITS chest data from human subjects demonstrates that the selected imaging strategy can effectively produce high-quality MITS thoracic images in vivo.

  2. Sensitivity analysis of the GEMS soil organic carbon model to land cover land use classification uncertainties under different climate scenarios in Senegal

    Directory of Open Access Journals (Sweden)

    A. M. Dieye

    2011-07-01

    Full Text Available Spatially explicit land cover land use (LCLU change information is needed to drive biogeochemical models that simulate soil organic carbon (SOC dynamics. Such information is increasingly being mapped using remotely sensed satellite data with classification schemes and uncertainties constrained by the sensing system, classification algorithms and land cover schemes. In this study, automated LCLU classification of multi-temporal Landsat satellite data were used to assess the sensitivity of SOC modeled by the Global Ensemble Biogeochemical Modeling System (GEMS. The GEMS was run for an area of 1560 km2 in Senegal under three climate change scenarios with LCLU maps generated using different Landsat classification approaches. This research provides a method to estimate the variability of SOC, specifically the SOC uncertainty due to satellite classification errors, which we show is dependent not only on the LCLU classification errors but also on where the LCLU classes occur relative to the other GEMS model inputs.

  3. Sensitivity analysis of the GEMS soil organic carbon model to land cover land use classification uncertainties under different climate scenarios in senegal

    Directory of Open Access Journals (Sweden)

    A. M. Dieye

    2012-02-01

    Full Text Available Spatially explicit land cover land use (LCLU change information is needed to drive biogeochemical models that simulate soil organic carbon (SOC dynamics. Such information is increasingly being mapped using remotely sensed satellite data with classification schemes and uncertainties constrained by the sensing system, classification algorithms and land cover schemes. In this study, automated LCLU classification of multi-temporal Landsat satellite data were used to assess the sensitivity of SOC modeled by the Global Ensemble Biogeochemical Modeling System (GEMS. The GEMS was run for an area of 1560 km2 in Senegal under three climate change scenarios with LCLU maps generated using different Landsat classification approaches. This research provides a method to estimate the variability of SOC, specifically the SOC uncertainty due to satellite classification errors, which we show is dependent not only on the LCLU classification errors but also on where the LCLU classes occur relative to the other GEMS model inputs.

  4. Sensitivity analysis of the GEMS soil organic carbon model to land cover land use classification uncertainties under different climate scenarios in Senegal

    Science.gov (United States)

    Dieye, A.M.; Roy, D.P.; Hanan, N.P.; Liu, S.; Hansen, M.; Toure, A.

    2011-01-01

    Spatially explicit land cover land use (LCLU) change information is needed to drive biogeochemical models that simulate soil organic carbon (SOC) dynamics. Such information is increasingly being mapped using remotely sensed satellite data with classification schemes and uncertainties constrained by the sensing system, classification algorithms and land cover schemes. In this study, automated LCLU classification of multi-temporal Landsat satellite data were used to assess the sensitivity of SOC modeled by the Global Ensemble Biogeochemical Modeling System (GEMS). The GEMS was run for an area of 1560 km2 in Senegal under three climate change scenarios with LCLU maps generated using different Landsat classification approaches. This research provides a method to estimate the variability of SOC, specifically the SOC uncertainty due to satellite classification errors, which we show is dependent not only on the LCLU classification errors but also on where the LCLU classes occur relative to the other GEMS model inputs. ?? 2011 Author(s).

  5. Sensitivity analysis of the GEMS soil organic carbon model to land cover land use classification uncertainties under different climate scenarios in senegal

    Science.gov (United States)

    Dieye, A. M.; Roy, D. P.; Hanan, N. P.; Liu, S.; Hansen, M.; Touré, A.

    2012-02-01

    Spatially explicit land cover land use (LCLU) change information is needed to drive biogeochemical models that simulate soil organic carbon (SOC) dynamics. Such information is increasingly being mapped using remotely sensed satellite data with classification schemes and uncertainties constrained by the sensing system, classification algorithms and land cover schemes. In this study, automated LCLU classification of multi-temporal Landsat satellite data were used to assess the sensitivity of SOC modeled by the Global Ensemble Biogeochemical Modeling System (GEMS). The GEMS was run for an area of 1560 km2 in Senegal under three climate change scenarios with LCLU maps generated using different Landsat classification approaches. This research provides a method to estimate the variability of SOC, specifically the SOC uncertainty due to satellite classification errors, which we show is dependent not only on the LCLU classification errors but also on where the LCLU classes occur relative to the other GEMS model inputs.

  6. Imaging of high-Z material for nuclear contraband detection with a minimal prototype of a Muon Tomography station based on GEM detectors

    CERN Document Server

    Gnanvo, Kondo; Hohlmann, Marcus; Locke, Judson B; Quintero, Amilkar S; Mitra, Debasis

    2010-01-01

    Muon Tomography based on the measurement of multiple scattering of atmospheric cosmic ray muons in matter is a promising technique for detecting heavily shielded high-Z radioactive materials (U, Pu) in cargo or vehicles. The technique uses the deflection of cosmic ray muons in matter to perform tomographic imaging of high-Z material inside a probed volume. A Muon Tomography Station (MTS) requires position-sensitive detectors with high spatial resolution for optimal tracking of incoming and outgoing cosmic ray muons. Micro Pattern Gaseous Detector (MPGD) technologies such as Gas Electron Multiplier (GEM) detectors are excellent candidates for this application. We have built and operated a minimal MTS prototype based on 30cm \\times 30cm GEM detectors for probing targets with various Z values inside the MTS volume. We report the first successful detection and imaging of medium-Z and high-Z targets of small volumes (~0.03 liters) using GEM-based Muon Tomography.

  7. Oxidation of gem-chloronitroso- and vic-chloronitroso-alkanes and -cycloalkanes to respective chloronitro compounds by novel cetyltrimethylammonium hypochlorite reagent

    Indian Academy of Sciences (India)

    Abdulkarim H A Mohammed; Gopalpur Nagendrappa

    2011-07-01

    Cetyltrimethylammonium hypochlorite (CTAHC) is prepared and used as an oxidizing agent for nitroso group to nitro group. The gem-chloronitroso and vic-chloronitroso compounds are prepared respectively from ketoximes and olefins by reacting with NOCl generated in situ from chlorotrimethylsilane (TMSCl) and iso-amyl nitrite. CTAHC oxidizes gem-chloronitroso and vic-chloronitroso compounds to the corresponding chloronitro derivatives. While gem-chloronitro compounds are obtained in good yields, the vic-chloronitro derivatives are formed in moderate yields, because of the propensity of the vic-chloronitroso group to tautomerize to -chlorooxime. The present method is simple and practical, particularly for the preparation of vic-chloronitro compounds, considering the fact that the known methods of their preparation are few and quite involved.

  8. Lenalidomid und Dexamethason in Kombination mit verschiedenen Zytostatika bei intensiv vortherapierten Patienten mit refraktärem oder rezidiviertem multiplem Myelom und primär systemischer Amyloidose

    OpenAIRE

    Hoffmann, Carolin

    2011-01-01

    Das multiple Myelom ist eine Erkrankung der Plasmazellen mit einer unkontrollierten Produktion an Immunglobulinen und macht etwa 10% aller hämatologischen Erkrankungen aus. Bisher stellt die Stammzelltransplantation für die jüngeren Patienten und die Chemotherapie für die älteren Erkrankten die Standardtherapie für diese unheilbare Krankheit dar. Fast immer kommt es allerdings zu einem Rezidiv. Für eine solche Situation gibt es bisher kein festes Behandlungsschema. In den letzten Jahren ist e...

  9. Die Kunst des Reg(istrierens mit Big Data Ein Versuch über Digitale Selbstverteidigung und Aktive Medienarbeit mit Daten

    Directory of Open Access Journals (Sweden)

    Valentin Dander

    2014-12-01

    Full Text Available Der Beitrag gibt Einblick in den Zusammenhang von Big Data Analytics und digitalen Überwachungspraktiken. Davon ausgehend werden mögliche Antworten auf die Frage nach medienpädagogischen Konsequenzen in Theorie und Praxis gegeben. Vorgeschlagen wird dabei eine Verschränkung von kritischer Analyse und aktiver Medienarbeit mit Daten. This article provides readers with an overview on the complex of Big Data and digital surveillance practices. In a second step practical as well as theoretical consequences for media education are being asked for. It is suggested to answer this question by an entanglement of critical analysis and productive involvement with data.

  10. Hormonprofilveränderungen unter DHEA-Substitution bei Patienten mit erektiler Dysfunktion

    Directory of Open Access Journals (Sweden)

    Reiter WJ

    2001-01-01

    Full Text Available Dehydroepiandrosteron (DHEA ist das verbreitetste Hormon im menschlichen Körper und wird der Gruppe der Steroidhormone zugeordnet. Nach Bildung in der Zona reticularis der Nebennierenrinde wird es mit Hilfe des Leberenzyms Dehydroepiandrosteronsulfotransferase in das Sulfat Dehydroepiandrosteronsulfat (DHEAS umgewandelt, zirkuliert so relativ stabil im Blut und wird in die Sexualhormone Testosteron und Östrogen im Gewebe transformiert. Eine bisher wissenschaftlich nicht abgeklärte Frage ist die Wirkung einer DHEA-Substitution auf die Serumspiegel der Sexualhormone beim Mann. Zu diesem Zweck wurden an allen Patienten mit ED, die an unserer Klinik und in zwei urologischen Kassenpraxen dieser Hormonsubstitution unterzogen wurden, im Rahmen einer prospektiven Studie ein Monitoring der wichtigsten Sexualhormone durchgeführt. Zwischen Oktober 1997 und Februar 2000 wurden 187 Patienten mit einem mittleren Alter von 52,4 Jahren, welche primär unsere Ambulanz oder zwei urologische Kassenpraxen wegen einer ED aufsuchten, nach urologischer und endokrinologischer Abklärung in diese prospektive, offene Studie aufgenommen. Alle Patienten wurden sorgfältig auf medizinische Faktoren untersucht, die einen Einfluß auf endokrinologische Abläufe haben könnten. Jeder Patient wurde mit einer Kapsel DHEA 50 mg 1 x 1 tgl. therapiert und für einen geplanten Studienzeitraum von 6 Monaten in die Studie aufgenommen. Eine statistisch signifikante Veränderung zeigten nur die Östradiolwerte. Dieser Anstieg schon begann 3 Monaten und diese Tendenz wurde bis zum Studienende beibehalten. Es konnte in dieser prospektiven Studie erstmalig in einem großen Patientenkollektiv gezeigt werden, daß sich bei männlichen Patienten mit erektiler Dysfunktion nach Substitutionstherapie mit 50 mg DHEA einmal tgl. eine statistisch signifikante Steigerung der Östradiolwerte, jedoch keine Veränderung der Testosteronwerte nachweisen läßt. Ob nun die DHEA-Wirkung beim ED

  11. Bayesian wavelet-based image deconvolution: a GEM algorithm exploiting a class of heavy-tailed priors.

    Science.gov (United States)

    Bioucas-Dias, José M

    2006-04-01

    Image deconvolution is formulated in the wavelet domain under the Bayesian framework. The well-known sparsity of the wavelet coefficients of real-world images is modeled by heavy-tailed priors belonging to the Gaussian scale mixture (GSM) class; i.e., priors given by a linear (finite of infinite) combination of Gaussian densities. This class includes, among others, the generalized Gaussian, the Jeffreys, and the Gaussian mixture priors. Necessary and sufficient conditions are stated under which the prior induced by a thresholding/shrinking denoising rule is a GSM. This result is then used to show that the prior induced by the "nonnegative garrote" thresholding/shrinking rule, herein termed the garrote prior, is a GSM. To compute the maximum a posteriori estimate, we propose a new generalized expectation maximization (GEM) algorithm, where the missing variables are the scale factors of the GSM densities. The maximization step of the underlying expectation maximization algorithm is replaced with a linear stationary second-order iterative method. The result is a GEM algorithm of O(N log N) computational complexity. In a series of benchmark tests, the proposed approach outperforms or performs similarly to state-of-the art methods, demanding comparable (in some cases, much less) computational complexity.

  12. Color, Structure, and Star Formation History of Dwarf Galaxies over the last ~3 Gyr with GEMS and SDSS

    CERN Document Server

    Barazza, F D; Bell, E F; Caldwell, J A R; Jogee, S; McIntosh, D H; Meisenheimer, K; Peng, C Y; Rix, H W; Wolf, C; Barazza, Fabio D.; Barden, Marco; Bell, Eric F.; Caldwell, John A. R.; Intosh, Daniel H. Mc; Jogee, Shardha; Meisenheimer, Klaus; Peng, Chien Y.; Rix, Hans-Walter; Wolf, Christian

    2006-01-01

    We present a study of the colors, structural properties, and star formation histories for a sample of ~1600 dwarfs over look-back times of ~3 Gyr (z=0.002-0.25). The sample consists of 401 distant dwarfs drawn from the Galaxy Evolution from Morphologies and SEDs (GEMS) survey, which provides high resolution Hubble Space Telescope (HST) Advanced Camera for Surveys (ACS) images and accurate redshifts, and of 1291 dwarfs at 10-90 Mpc compiled from the Sloan Digitized Sky Survey (SDSS). The sample is complete down to an effective surface brightness of 22 mag arcsec^-2 in z and includes dwarfs with M_g=-18.5 to -14 mag. Rest-frame luminosities in Johnson UBV and SDSS ugr filters are provided by the COMBO-17 survey and structural parameters have been determined by S\\'ersic fits. We find that the GEMS dwarfs are bluer than the SDSS dwarfs by ~0.13 mag in g-r, which is consistent with the color evolution over ~2 Gyr of star formation histories involving moderate starbursts and long periods of continuous star formatio...

  13. Check and After-market Performance of GEM IPO%创业板IPO审核及后市表现

    Institute of Scientific and Technical Information of China (English)

    胡蕾

    2015-01-01

    本文研究拟在创业板上市的企业可能面临的IPO审核方面的问题,以及企业在IPO后业绩的表现.创业板市场是为具有创新型和成长型企业设立的一个新的融资渠道,其上市标准低于主板市场,审核发行上市时不注重当前的公司业绩,这样的"低门槛"会给投资者带来一定的风险,所以企业在成功IPO后的业绩表现如何成为应该关注的重点,即IPO的后市表现.%This paper researches the IPO check problems for GEM listing enterprises, and the business performance after IPO. GEM market is a new funding channel for innovative and growing enterprises, the listing standard of which is lower than mainboard markey. The check of listing doesn't pay attention to the present enterprise performance, which brings the risk to investors. Therefore, the focus should be the performance after IPC of enterprise, namely IPO after-market performance.

  14. A generalized electrostatic micro-mirror (GEM) model for a two-axis convex piecewise linear shaped MEMS mirror

    Science.gov (United States)

    Edwards, C. L.; Edwards, M. L.

    2009-05-01

    MEMS micro-mirror technology offers the opportunity to replace larger optical actuators with smaller, faster ones for lidar, network switching, and other beam steering applications. Recent developments in modeling and simulation of MEMS two-axis (tip-tilt) mirrors have resulted in closed-form solutions that are expressed in terms of physical, electrical and environmental parameters related to the MEMS device. The closed-form analytical expressions enable dynamic time-domain simulations without excessive computational overhead and are referred to as the Micro-mirror Pointing Model (MPM). Additionally, these first-principle models have been experimentally validated with in-situ static, dynamic, and stochastic measurements illustrating their reliability. These models have assumed that the mirror has a rectangular shape. Because the corners can limit the dynamic operation of a rectangular mirror, it is desirable to shape the mirror, e.g., mitering the corners. Presented in this paper is the formulation of a generalized electrostatic micromirror (GEM) model with an arbitrary convex piecewise linear shape that is readily implemented in MATLAB and SIMULINK for steady-state and dynamic simulations. Additionally, such a model permits an arbitrary shaped mirror to be approximated as a series of linearly tapered segments. Previously, "effective area" arguments were used to model a non-rectangular shaped mirror with an equivalent rectangular one. The GEM model shows the limitations of this approach and provides a pre-fabrication tool for designing mirror shapes.

  15. The PHASES Differential Astrometry Data Archive IV: The Triple Star Systems 63 Gem A and HR 2896

    CERN Document Server

    Muterspaugh, Matthew W; Lane, Benjamin F; Hartkopf, William I; Kulkarni, S R; Konacki, Maciej; Burke, Bernard F; Colavita, M M; Shao, M; Williamson, M

    2010-01-01

    (Abridged) Differential astrometry measurements from the Palomar High-precision Astrometric Search for Exoplanet Systems (PHASES) are used to constrain the astrometric orbit of the previously known lesssim 2 day subsystem in the triple system 63 Gem A and have detected a previously unknown 2 year Keplerian wobble superimposed on the visual orbit of the much longer period (213 years) binary system HR 2896. The very small astrometric perturbation caused by the inner pair in 63 Gem A stretches the limits of current astrometric capabilities, but PHASES observations are able to constrain the orientation of the orbit. The two bright stars comprising the HR 2896 long period (213 year) system have a combined spectral type of K0III and the newly detected object's mass estimate places it in the regime of being a M dwarf. The motion of the stars are slow enough that their spectral features are always blended, preventing Doppler studies. The PHASES measurements and radial velocities (when available) have been combined wi...

  16. Real-time implementation of an LQG tip-tilt controller for regular science observation on GeMS

    Science.gov (United States)

    Sivo, Gaetano; Juvénal, Rémy; Kulcsár, Caroline; Garrel, Vincent; Gigoux, Pedro; Raynaud, Henri-François; Marin, Eduardo; Conan, Jean-Marc; Petit, Cyril; Rambold, William; Montes, Vanessa; Moreno, Cristian; Donahue, Jeff; Carrasco, Rodrigo; van Dam, Marcos; Neichel, Benoît; Leboulleux, Lucie; Trujillo, Chad

    2016-07-01

    AO systems aim at detecting and correcting for optical distortions induced by atmospheric turbulences. They are also extremely sensitive to extraneous sources of perturbation such as vibrations, which degrade the performance. The Gemini South telescope has currently two main AO systems: the Gemini Multi Conjugated AO System GeMS and the Gemini Planet Imager GPI. GeMS is operational and regularly used for science observation delivering close to diffraction limit resolution over a large field of view (85×85 arcsec2). Performance limitation due to the use of an integrator for tip-tilt control is here explored. In particular, this type of controller does not allow for the mitigation of vibrations with an arbitrary natural frequency. We have thus implemented a tip-tilt Linear Quadratic Gaussian (LQG) controller with different underlying perturbation models: (i) a sum of autoregressive models of order 2 identified from an estimated power spectrum density (s-AR2) of the perturbation,1 already tested on CANARY2 and routinely used on SPHERE;3 (ii) cascaded ARMA models of order 2 identified using prediction error minimization (c-PEM) as proposed in.4, 5 Both s-AR2 and c-PEM were parameterized to produce tip or tilt state-space models up to order 20 and 30 respectively. We discuss the parallelized implementation in the real time computer and the expected performance. On-sky tests are scheduled during the November 2016 run or the January 2017 run.

  17. Die Dramatikerin Theresia Walser spricht mit Maria Aparecida Barbosa über das Theaterstück "King Kongs Töchter":Mit einer Einführung von Karina Schuller

    OpenAIRE

    2012-01-01

    In ihrem Interview spricht die Literaturwissenschaftlerin Maria Aparecida Barbosa mit der Dramatikerin Theresia Walser. Am Beispiel des Theaterstücks King Kongs Töchter (1998), das sich auf groteske Art und Weise mit dem Alltag in einem Altenheim befasst, werden dabei verschiedene Themen angesprochen: Es geht um die Selbstreflexivität des Theaters, um Walsers Verständnis von poetischer Sprache und Realismus sowie um den kreativen Schreibprozess im Allgemeinen. Ergänzt wird das Interview durch...

  18. KoelnArena has 18,000 seats; Die KoelnArena mit 18 000 Sitzplaetzen

    Energy Technology Data Exchange (ETDEWEB)

    Zerres, E.

    1999-06-01

    The ``Koelnarena`` is a new hall with 18,000 seats for sports events and cultural events, and with a skating rink in the hall center. In view of the many events (up to 180 per year), the skating rink must be glazed throughout the year (except for the summer holidays) in order to avoid the high cost of frequent freezing and thawing. [Deutsch] Die Koelnarena ist eine neue Halle fuer 18 000 Besucher in Koeln-Deutz, mit vielfacher Verwendbarkeit fuer Eishockey und Eistanz, Tennis, Volleyball, Boxen, Schausport, Showkonzerte, Oper und Tanzveranstaltungen. Das Kernstueck dieser MEGA-Halle ist die Eispiste in der Hallenmitte. Wegen der hohen Auslastung der Halle mit bis zu 180 Veranstaltungen pro Jahr muss die Eispiste ganzjaehrig (ausser waehrend der Sommerferien) vereist bleiben, um den sehr grossen Energieaufwand fuer haeufig Eisbildung (und Abtauen.) sowie die Kosten hierfuer zu vermeiden. (orig.)

  19. Center for Multiscale Plasma Dynamics: Report on Activities (UCLA/MIT), 2009-2010

    Energy Technology Data Exchange (ETDEWEB)

    Carter, Troy Alan [Univ. of California, Los Angeles, CA (United States)

    2014-10-03

    The final “phaseout” year of the CMPD ended July 2010; a no cost extension was requested until May 2011 in order to enable the MIT subcontract funds to be fully utilized. Research progress over this time included verification and validation activities for the BOUT and BOUT++ code, studies of spontaneous reconnection in the VTF facility at MIT, and studies of the interaction between Alfv´en waves and drift waves in LAPD. The CMPD also hosted the 6th plasma physics winter school in 2010 (jointly with the NSF frontier center the Center for Magnetic Self-Organization, significant funding came from NSF for this most recent iteration of theWinter School).

  20. Contribution of occupational therapy for patients with depression / Beitrag der Ergotherapie in der Wahrnehmung von Menschen mit Depression

    Directory of Open Access Journals (Sweden)

    Treusch Yvonne

    2016-12-01

    Full Text Available In Bezug auf den professionellen Beitrag und die Wirkfaktoren der Ergotherapie bei Menschen mit Depression existieren bislang wenige Studien. Dies steht im Kontrast zum praktischen und quantitativen Beitrag dieser Therapieform.