WorldWideScience

Sample records for ausleseprototyp mit gems

  1. Graphics gems

    CERN Document Server

    Glassner, Andrew S

    1993-01-01

    ""The GRAPHICS GEMS Series"" was started in 1990 by Andrew Glassner. The vision and purpose of the Series was - and still is - to provide tips, techniques, and algorithms for graphics programmers. All of the gems are written by programmers who work in the field and are motivated by a common desire to share interesting ideas and tools with their colleagues. Each volume provides a new set of innovative solutions to a variety of programming problems.

  2. Graphics gems

    CERN Document Server

    Heckbert, Paul S

    1994-01-01

    Graphics Gems IV contains practical techniques for 2D and 3D modeling, animation, rendering, and image processing. The book presents articles on polygons and polyhedral; a mix of formulas, optimized algorithms, and tutorial information on the geometry of 2D, 3D, and n-D space; transformations; and parametric curves and surfaces. The text also includes articles on ray tracing; shading 3D models; and frame buffer techniques. Articles on image processing; algorithms for graphical layout; basic interpolation methods; and subroutine libraries for vector and matrix algebra are also demonstrated. Com

  3. GPU Computing Gems Emerald Edition

    CERN Document Server

    Hwu, Wen-mei W

    2011-01-01

    ".the perfect companion to Programming Massively Parallel Processors by Hwu & Kirk." -Nicolas Pinto, Research Scientist at Harvard & MIT, NVIDIA Fellow 2009-2010 Graphics processing units (GPUs) can do much more than render graphics. Scientists and researchers increasingly look to GPUs to improve the efficiency and performance of computationally-intensive experiments across a range of disciplines. GPU Computing Gems: Emerald Edition brings their techniques to you, showcasing GPU-based solutions including: Black hole simulations with CUDA GPU-accelerated computation and interactive display of

  4. Gas amplification properties of GEM foils; Gasverstaerkungseigenschaften von GEM-Folien

    Energy Technology Data Exchange (ETDEWEB)

    Beck, Jeannine

    2009-01-15

    procedure were developed and a laser-measurement arrangement for the measurement of GEM surface profiles designed and tested. The Planeness of framed GEM foils was determined, whereby height differences up to 1 mm resulted. [German] Im Rahmen des Detektorkonzeptes International Linear Detector fuer das kuenftige Beschleunigerprojekt International Linear Collider, an dem Elektronen und Positronen bei Schwerpunktsenergien von 500 GeV zur Kollision gebracht werden, soll eine Zeit-Projektions-Kammer als zentrale Spurkammer eingesetzt werden. Mit der Verwendung einer derartigen Kammer als Spurdetektor ist eine dreidimensionale Rekonstruktion der Spurpunkte moeglich. Durchfliegt ein Teilchen das Gasvolumen innerhalb der Kammer, ionisiert es einzelne Gasatome und die entstandenen Elektronen bewegen sich nach der Verstaerkung in der GEM-Anordnung (engl. Gas Electron Multiplier) zur Anode, so dass eine zweidimensionale Projektion der Teilchenspur moeglich ist. Die dritte Dimension wird aus der Driftzeit der Elektronen errechnet. Die Vorteile dieses Auslesesystems bestehen darin, dass eine bessere Ortsaufloesung als mit einer Vieldraht-Proportional-Kammer erreicht wird und die rueckdriftenden Ionen stark unterdrueckt werden koennen. Ziel dieser Arbeit sind Untersuchungen fuer ein GEM-Modul, das in einem grossen TPCPrototypen genutzt werden soll. Hinsichtlich verschiedener Anforderungen gilt es unterschiedliche GEMs zu vergleichen, um eine optimale Auswahl treffen zu koennen. In einem am DESY vorhandenen kleinen Prototypen wurden Messungen zur Erfassung von GEM-beschreibenden Parametern durchgefuehrt. Die Inbetriebnahme der Test-TPC war Bestandteil dieser Arbeit. Es wurden Spuren durch eine radioaktive Quelle erzeugt, mit deren Hilfe die Gasverstaerkung bestimmt wurde. Mit dem Messaufbau wurden verschiedenartige Gasverstaerkerfolien hinsichtlich ihrer Verstaerkungseigenschaften und ihres Energieaufloesungsvermoegens verglichen und systematisch studiert. Es wurden fuenf

  5. Not Your Ordinary GEM

    Science.gov (United States)

    2001-01-01

    Through Small Business Innovation Research (SBIR) funding from NASA's Stennis Space Center, Geophex devised a new design for broadband electromagnetic sensors. Geophex developed a patented sensing technology, capable not only of coastal monitoring, but also a variety of other functions, including environmental pollution characterization, groundwater contamination detection, archaeological study, and mineral detection. The new technology is offered in several of the company's products the GEM-2, GEM-2A, and the GEM-3. The Geophex products consist of two primary electromagnetic coils, which are stimulated by alternating currents that generate a magnetic field in the object targeted for investigation. GEM-2 is a handheld, lightweight, programmable, digital device. GEM-2A is an airborne version of the sensor. Suspended from a helicopter, the GEM-2A is used to search for mineral deposits and to survey large tracts of land. The GEM-3 is capable of detecting buried landmines and other active munitions. GEM-3 identifies landmines by their brand names. Because each landmine has its own unique electromagnetic response to the broad frequency band emitted by the GEM-3, bomb identification and disposal strategies are made easier.

  6. GEM Detector Electric Field Simulation

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    GEM (Gas Electron Multiplier) detectors have been widely employed in the experimental field of high energy physics and nuclear physics. As a successor to drift chambers, GEMs are much easier to fabricate and have a much higher spatial resolution

  7. GEM Technical Design Report

    International Nuclear Information System (INIS)

    The GEM collaboration was formed in June 1991 to develop a major detector for the SSC. The primary physics objectives of GEM are those central to the motivation for the SSC, to study high pT physics - exemplified by the search for Higgs bosons - and to search for new physics beyond the standard model. The authors present in this Technical Design Report (TDR) a detector with broad capabilities for the discovery and subsequent study of electroweak symmetry breaking, the origin of mass and flavor, and other physics requiring precise measurements of gammas, electrons, and muons - hence the name, GEM. In addition, as a design goal, they have taken care to provide the robustness needed to do the physics that requires high luminosity. Finally, good coverage and hermeticity allow the detection of missing transverse energy, ET. The GEM design emphasizes clean identification and high resolution measurement of the primary physics signatures for high pT physics. The approach is to make precise energy measurements that maximize the sensitivity to rare narrow resonances, to detect the elementary interaction products (quarks, leptons, and photons), and to build in the features required to reduce backgrounds

  8. GEM Technical Design Report

    Energy Technology Data Exchange (ETDEWEB)

    1993-07-31

    The GEM collaboration was formed in June 1991 to develop a major detector for the SSC. The primary physics objectives of GEM are those central to the motivation for the SSC, to study high p{sub T} physics - exemplified by the search for Higgs bosons - and to search for new physics beyond the standard model. The authors present in this Technical Design Report (TDR) a detector with broad capabilities for the discovery and subsequent study of electroweak symmetry breaking, the origin of mass and flavor, and other physics requiring precise measurements of gammas, electrons, and muons - hence the name, GEM. In addition, as a design goal, they have taken care to provide the robustness needed to do the physics that requires high luminosity. Finally, good coverage and hermeticity allow the detection of missing transverse energy, E{sub T}. The GEM design emphasizes clean identification and high resolution measurement of the primary physics signatures for high p{sub T} physics. The approach is to make precise energy measurements that maximize the sensitivity to rare narrow resonances, to detect the elementary interaction products (quarks, leptons, and photons), and to build in the features required to reduce backgrounds.

  9. Mit kokkeri

    DEFF Research Database (Denmark)

    Ejlersen, Søren; Lorang, Louisa

    MIT kokkeri er resultatet af et samarbejde mellem Komiteen for Sundhedsoplysning, Institut for Uddannelse og Pædagogik/Aarhus Universitet og Haver til Maver. Projektet støttes af Nordea-fonden. Bag kogebogens mange opskrifter står en række erfarne madeksperter bestående af Søren Ejlersen, Louisa ...

  10. Graphics Gems III IBM version

    CERN Document Server

    Kirk, David

    1994-01-01

    This sequel to Graphics Gems (Academic Press, 1990), and Graphics Gems II (Academic Press, 1991) is a practical collection of computer graphics programming tools and techniques. Graphics Gems III contains a larger percentage of gems related to modeling and rendering, particularly lighting and shading. This new edition also covers image processing, numerical and programming techniques, modeling and transformations, 2D and 3D geometry and algorithms,ray tracing and radiosity, rendering, and more clever new tools and tricks for graphics programming. Volume III also includes a

  11. Graphics gems V (Macintosh version)

    CERN Document Server

    Paeth, Alan W

    1995-01-01

    Graphics Gems V is the newest volume in The Graphics Gems Series. It is intended to provide the graphics community with a set of practical tools for implementing new ideas and techniques, and to offer working solutions to real programming problems. These tools are written by a wide variety of graphics programmers from industry, academia, and research. The books in the series have become essential, time-saving tools for many programmers.Latest collection of graphics tips in The Graphics Gems Series written by the leading programmers in the field.Contains over 50 new gems displaying some of t

  12. Graphics gems II

    CERN Document Server

    Arvo, James

    1991-01-01

    Graphics Gems II is a collection of articles shared by a diverse group of people that reflect ideas and approaches in graphics programming which can benefit other computer graphics programmers.This volume presents techniques for doing well-known graphics operations faster or easier. The book contains chapters devoted to topics on two-dimensional and three-dimensional geometry and algorithms, image processing, frame buffer techniques, and ray tracing techniques. The radiosity approach, matrix techniques, and numerical and programming techniques are likewise discussed.Graphics artists and comput

  13. Characterizations of GEM detector prototype

    CERN Document Server

    Patra, Rajendra Nath; Rudra, Sharmili; Bhattacharya, P; Sahoo, Sumanya Sekhar; Biswas, S; Mohanty, B; Nayak, T K; Sahu, P K; Sahu, S

    2015-01-01

    At NISER-IoP detector laboratory an initiative is taken to build and test Gas Electron Multiplier (GEM) detectors for ALICE experiment. The optimisation of the gas flow rate and the long-term stability test of the GEM detector are performed. The method and test results are presented.

  14. Bedeutung des Gemüsebaus für die Landwirtschaft von Wielkopolska

    Directory of Open Access Journals (Sweden)

    Karolina Jąder

    2009-01-01

    Full Text Available In dem Artikel wurde die Bedeutung des Gemüsebaus für die Landwirtschaft der Region Wielkopolska präsentiert. Diese Bedeutung wurde mit Hilfe von einigen Kriterien bestimmt. Es wurden dargestellt: der Anteil der Gemüsefläche an der gesamten landwirtschaftlichen Nutzfläche von Wielkopolska und der Gemüseanteil in der Brutto- und Warenproduktion der regionalen Landwirtschaft und der Pflanzenabteilung. Der Anteil der Freilandgemüsefläche an der landwirtschaftlichen Nutzfläche lag bei 1,36 bis 1,56 Prozent und der Anteil der Gewächshausgemüsefläche an der landwirtschaftlichen Nutzfläche oszillierte von 0,017 bis 0,050 Prozent. Die Gemüseproduktion lag bei 4,67 Prozent der Bruttoproduktion der Landwirtschaft von Wielkopolska, und der Anteil der Gemüseproduktion an der Warenproduktion der Landwirtschaft war in der Zeit auf einem ähnlichen Niveau – 4,66 Prozent. In der Pflanzenabteilung war die Bedeutung des Gemüsebaus noch größer als in der ganzen Landwirtschaft. Der Anteil von Gemüse an der Warenproduktion der Pflanzenabteilung lag durchschnittlich in den untersuchten Jahren bei 28, 54 Prozent.

  15. Mexican gems as thermoluminescent dosimeters

    International Nuclear Information System (INIS)

    The possibility of using naturally ocurring mexican gems as thermoluminescent dosimeters (TLD) was investigated. Twelve types of gems were irradiated with X and gamma rays in order to determinate their dosimetric properties. Three of these gems showed favorable thermoluminescent characteristics compared with commercial thermoluminescent dosimeters. The plots of their thermoluminescent response as a function of gamma dose are straight lines on full log paper in the dose range 10-2 to 102 Gy. The energy dependence is very strong to low energies of the radiation. Their fading was found to be about 5%/yr. and they may be annealed as reused without loss in sensitivity. Therefore, these gems can be used as X and gamma radiation dosimeters. (author)

  16. Technical Summaries of GEMS

    Institute of Scientific and Technical Information of China (English)

    孙家广; 辜凯宁; 等

    1989-01-01

    GEMS is a solid modelling system running on CAS workstation or 32 bits microcomputer with graphics terminal.Complex solid obj ects are built from transformation and set operations upon box,cylinder,cone,sphere,torus,sweeping object and other primitives.CEMS has explicit reatures.e.g.hierarchical modular structure, interactive user interfaceintuitional input,screen menu driven by data table,defining and instancing object in network construction,storage bases on CSG(Constructive Solid Geometry)and BReps(Boundary Representations).regularized set operations,transformation pipeline consistent with PHIGS graphics standard,various transformations,cutting object with two sections in arbitrary angle,patrolling to view the inside of an object,mapping patterns onto surfaces of an object etc.,Not only can it be used for the fields of spatial planning,architectural plan,CAD/CAM for machining,structure analysis,but it is also fundamental for developing the practical system of simulation,computer vision,robotics and so on.

  17. Origin and properties of GEMS

    Energy Technology Data Exchange (ETDEWEB)

    Dai, Z R; Bradley, J P

    2006-04-11

    GEMS are to the outer solar system what chondrules are to the inner solar system. Ten years after it was first proposed that GEMS are the long-sought interstellar amorphous silicates, ion microprobe measurements have confirmed that some of them are indeed interstellar amorphous silicates. The new challenges are to obtain even higher precision isotope measurements from these submicrometer-sized objects and to clarify how and where they originally formed. Individual GEMS exhibit a strikingly narrow (0.1-0.5 {micro}m diameter) size distribution and they are systematically depleted from solar abundances in S/Si, Mg/Si, Ca/Si and Fe/Si, implying that they formed by a common mechanism. Mineralogical and petrographic evidence suggest that irradiation processing may be that mechanism. Recent nanometer-scale compositional mapping using new-generation transmission electron microscopes reveals that truly pristine GEMS may be relatively rare and new metrics need to be developed to distinguish the primordial properties of GEMS from more recent secondary alteration effects.

  18. GEM - The Global Earthquake Model

    Science.gov (United States)

    Smolka, A.

    2009-04-01

    Over 500,000 people died in the last decade due to earthquakes and tsunamis, mostly in the developing world, where the risk is increasing due to rapid population growth. In many seismic regions, no hazard and risk models exist, and even where models do exist, they are intelligible only by experts, or available only for commercial purposes. The Global Earthquake Model (GEM) answers the need for an openly accessible risk management tool. GEM is an internationally sanctioned public private partnership initiated by the Organisation for Economic Cooperation and Development (OECD) which will establish an authoritative standard for calculating and communicating earthquake hazard and risk, and will be designed to serve as the critical instrument to support decisions and actions that reduce earthquake losses worldwide. GEM will integrate developments on the forefront of scientific and engineering knowledge of earthquakes, at global, regional and local scale. The work is organized in three modules: hazard, risk, and socio-economic impact. The hazard module calculates probabilities of earthquake occurrence and resulting shaking at any given location. The risk module calculates fatalities, injuries, and damage based on expected shaking, building vulnerability, and the distribution of population and of exposed values and facilities. The socio-economic impact module delivers tools for making educated decisions to mitigate and manage risk. GEM will be a versatile online tool, with open source code and a map-based graphical interface. The underlying data will be open wherever possible, and its modular input and output will be adapted to multiple user groups: scientists and engineers, risk managers and decision makers in the public and private sectors, and the public-at- large. GEM will be the first global model for seismic risk assessment at a national and regional scale, and aims to achieve broad scientific participation and independence. Its development will occur in a

  19. Science's gem: Diamond science 2009

    OpenAIRE

    MAINWOOD, A.; Newton, M. E.; STONEHAM, M.

    2009-01-01

    Natural diamond has been valued for its appearance and mechanical properties for at least two thousand years. As a gem stone diamond is unsurpassed. However, scientific work, especially in the last 20 years, has demonstrated that diamond has numerous surprising properties and many unique ones. Some of the extreme properties have been known for many years, but the true scale of diamond's other highly desirable features is still only coming to light as control in the synthesis of diamond, and h...

  20. Leading a successful iGEM team.

    Science.gov (United States)

    Materi, Wayne

    2012-01-01

    The International Genetically Engineered Machines (iGEM) competition allows undergraduate teams to develop projects in synthetic biology within the context of a large, international Jamboree. Organizing and managing a successful iGEM team is an exercise in advanced agile project development. While many of the principles applicable to such teams are derived from management of agile software teams, iGEM presents several unique challenges.

  1. Leading a successful iGEM team.

    Science.gov (United States)

    Materi, Wayne

    2012-01-01

    The International Genetically Engineered Machines (iGEM) competition allows undergraduate teams to develop projects in synthetic biology within the context of a large, international Jamboree. Organizing and managing a successful iGEM team is an exercise in advanced agile project development. While many of the principles applicable to such teams are derived from management of agile software teams, iGEM presents several unique challenges. PMID:22328439

  2. Ansatz und Bewertung originärer immaterieller Vermögensgegenständedes Anlagevermögens gemäß dem Gesetzentwurf zur Modernisierung des Bilanzrechts (Bilanzrechtsmodernisierungsgesetz – BilMoG) : Eine Betrachtung mit Blick auf die Informationsfunktion des Jahresabschlusses

    OpenAIRE

    Kramski, Alexandra

    2009-01-01

    Die vorliegende Arbeit befasst sich mit dem Ansatz und der Bewertung originärer immaterieller Vermögensgegenstände des Anlagevermögens im handelsrechtlichen Jahresabschluss. Es handelt sich hierbei um die Untersuchung der Frage, ob die Verpflichtung zur Aktivierung oben genannter Vermögensgegenstände die Aussagekraft eines Jahresabschlusses nach HGB erhöht. Während die internationalen Rechnungslegungsstandards (IFRS) den Ansatz immaterieller Vermögensgegenstände – unabhängig davon, ob sie ent...

  3. The GEMS-2 SEIS Experiment

    Science.gov (United States)

    Tillier, S.; De Raucourt, S.; Mimoun, D.; Lognonne, P.; Giardini, D.; Christensen, U. R.; Pike, W. T.; Banerdt, B.; Laudet, P.; Kerjean, L.; Hurst, K. J.; Zweifel, P.; Mance, D.; Roll, R.; Bierwirth, M.; Gagnepain-Beyneix, J.; Nibut, T.; Robert, O.; Gabsi, T.; Pot, O.; Lecomte, B.; Schibler, P.; Mocquet, A.; Garcia, R.

    2011-12-01

    The SEIS experiment is the primary payload of the Geophysical Monitoring Station (GEMS) Mission Proposal, submitted to NASA in the frame of the 2010 Discovery program, and recently selected for the phase A study. The objective of the GEMS SEIS experiment is the determination of the deep internal structure of Mars. In particular, geophysical parameters of first importance, such as the state (liquid/solid) and size of the core, as well as structure of the mantle and shape of discontinuities will be determined by the experiment. It will measure seismic activity in a very broad band of signal, from the tidal frequencies (0.05 mHz) up to the short period frequencies (50 Hz), to address the widest range of scientific questions, from the state of the inner core to the meteoritic rate measurement. Infrasound, which might be associated to dust devils and atmospheric discharge, will be also monitored. The instrument integrates a Very Broad Band (VBB) 3 axis seismometer, completed by another trihedron of MEMS short period seismometers, environmental sensors for pressure, wind and temperature, and an infrasound sensor is additionally considered. The sensors will be deployed on the Martian ground by a robotic arm from the Phoenix lander platform and protected by a wind and thermal shield. The sensor assembly, which contains all seismic sensors, the leveling system, as well as house-keeping and temperature measurements, will be deployed on the soil in order to allow the best possible mechanical coupling with the ground motion. Thanks to the wind and thermal shield, together with the sensors' specific containers (vacuum sphere for VBBs), long term VBB bias will be protected from both temperature and pressure variations (as well as passively compensated), allowing the sensor to operate in the rough Martian thermal environment. A dedicated electronics will manage the overall experiment and ultra-low noise, space qualified 24 bits A/D converters will perform the acquisition. The

  4. MITS machine operations

    International Nuclear Information System (INIS)

    This document contains procedures which apply to operations performed on individual P-1c machines in the Machine Interface Test System (MITS) at AiResearch Manufacturing Company's Torrance, California Facility

  5. Research and Development of GEM Foil at CIAE

    Institute of Scientific and Technical Information of China (English)

    LI; Xiao-mei; ZHOU; Jing; HU; Shou-yang; SHAN; Chao; JIAN; Si-yu; YE; Li; BAI; Xin-zhan; ZHOU; Shu-hua

    2012-01-01

    <正>China Institute of Atomic Energy has signed the "License Agreement for Manufacturing and Commercialisation of Gem Foils and Gem Based Products Licensee" with CERN, and got the technical assistance from CERN. The base material of GEM foil is ultrathin, non-adhesive copper on polyimide substrate, which can be purchased from CERN and other companies. The manufacture of GEM foil is

  6. Characterization of the GEM foil materials

    CERN Document Server

    Benussi, L; Saviano, G; Muhammad, S; Piccolo, D; Raffone, G; Caponero, M; Passamonti, L; Pierluigi, D; Russo, A; Primavera, F; Cerbelli, S; Lalli, A; Valente, M; Ferrini, M; Teissandier, B; Taborelli, M; Parvis, M; Grassini, S; Tirilló, J; Sarasini, F; Franchi, A V

    2015-01-01

    Systematic studies on the GEM foil material are performed to measure the moisture diffusion rate and saturation level. These studies are important because the presence of this compound inside the detector's foil can possibly change its mechanical and electrical properties and, in such a way, the detector performance can be affected. To understand this phenomenon, a model is developed with COMSOL Multhiphysics v. 4.3, which described the adsorption and diffusion within the geometry of GEM foil, the concentration profiles and the time required to saturate the foil. The COMSOL model is verified by experimental observations on a GEM foil sample. This note will describe the model and its experimental verification results.

  7. Commercial and Cost Effective Production of Gas Electron Multiplier (GEM) Foils

    Energy Technology Data Exchange (ETDEWEB)

    Woody, Craig

    2009-03-31

    The nuclear and high energy physics research community is constantly searching for new and improved tracking and radiation detectors. The introduction of micropattern detectors has opened new opportunities for improving the rate capabilities, as well as the spatial and time resolution of particle detectors in these applications. GEM detectors in particular have received enormous interest for use in detectors planned for a number of new and upgraded experiments at many different research facilities. These include both the STAR and PHENIX experiments at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory, experiments at the Thomas Jefferson National Laboratory, Oak Ridge National Laboratory, and at the future electron-positron Linear Collider. At the present time, CERN is not able to supply foils in sufficient quantities to accommodate the needs of these experiments. Compounding this problem, there is a strong interest in GEM foils for numerous other applications, such as in astrophysics, medical imaging and detectors for homeland security. It would therefore be of significant benefit to the research community to develop a commercial source of GEM foils for all of these applications. Tech-Etch is in a unique position to develop this technology for commercial use. Tech-Etch has not only experience in numerous related high precision etched Kapton® products, but it also has strong ties with several research institutions (namely Brookhaven, Yale and MIT) that can help develop and evaluate the performance of the GEM foils produced at Tech-Etch. Additionally, since Tech-Etch is a small company, it also has the capability to produce a large variety of part configurations, as well as the flexibility to shift production methods, equipment, and chemistry to optimize the GEM foil manufacturing process without being constrained by existing work running on high volume continuous coil equipment.

  8. Commercial and cost effective production of Gas Electron Multiplier (GEM) Foils

    Energy Technology Data Exchange (ETDEWEB)

    Crary, David

    2010-05-05

    The nuclear and high energy physics research community is constantly searching for new and improved tracking and radiation detectors. The introduction of micropattern detectors has opened new opportunities for improving the rate capabilities, as well as the spatial and time resolution of particle detectors in these applications. GEM detectors in particular have received enormous interest for use in detectors planned for a number of new and upgraded experiments at many different research facilities. These include both the STAR and PHENIX experiments at the Relativistic Heavy Ion Collider at Brookhaven National Laboratory, experiments at the Thomas Jefferson National Laboratory, Oak Ridge National Laboratory, and at the future electron-positron Linear Collider. At the present time, CERN is not able to supply foils in sufficient quantities to accommodate the needs of these experiments. Compounding this problem, there is a strong interest in GEM foils for numerous other applications, such as in astrophysics, medical imaging and detectors for homeland security. It would therefore be of significant benefit to the research community to develop a commercial source of GEM foils for all of these applications. Tech-Etch is in a unique position to develop this technology for commercial use. Tech-Etch has not only experience in numerous related high precision etched Kapton® products, but it also has strong ties with several research institutions (namely Brookhaven, Yale and MIT) that can help develop and evaluate the performance of the GEM foils produced at Tech-Etch. Additionally, since Tech-Etch is a small company, it also has the capability to produce a large variety of part configurations, as well as the flexibility to shift production methods, equipment, and chemistry to optimize the GEM foil manufacturing process without being constrained by existing work running on high volume continuous coil equipment.

  9. Development of large-area glass GEM

    Energy Technology Data Exchange (ETDEWEB)

    Mitsuya, Yuki, E-mail: yukimitsuya@sophie.q.t.u-tokyo.ac.jp [Department of Nuclear Engineering and Management, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8654 (Japan); Fujiwara, Takeshi [Research Institute for Measurement and Analytical Instrumentation, National Metrology Institute of Japan, National Institute of Advanced Industrial Science and Technology (AIST), Tsukuba Central 2, 1-1-1 Umezono, Tsukuba, Ibaraki 305-8568 (Japan); Fushie, Takashi [HOYA Corporation, 3280 Nakamaru, Nagasaka-cho, Hokuto-city, Yamanashi 408-8550 (Japan); Maekawa, Tatsuyuki [Toshiba Corporation, 8 Shinsugita-cho, Isogo-ku, Yokohama-city, Kanagawa 235-8523 (Japan); Takahashi, Hiroyuki [Department of Nuclear Engineering and Management, School of Engineering, The University of Tokyo, 7-3-1 Hongo, Bunkyo-ku, Tokyo 113-8654 (Japan)

    2015-09-21

    We have developed a new gaseous radiation detector, referred to as the Glass GEM (G-GEM). The G-GEM is composed of a photosensitive etching glass (PEG3) substrate from HOYA Corporation, Japan. Since a large-area detector is required for imaging device applications, we newly developed a large-area G-GEM prototype with a sensitive area of 280×280 mm{sup 2}. In this study, we investigated its basic characteristics and confirmed that it worked properly and had sufficient uniformity across the entire sensitive area. It had high gas gain of up to approximately 7700, along with good energy resolution of 26.2% (FWHM) for a 5.9-keV X-ray with a gas mixture of Ar (90%) and CH4 (10%). The gain variation across the sensitive area was almost within the range of ±10%.

  10. GEM Building Taxonomy (Version 2.0)

    Science.gov (United States)

    Brzev, S.; Scawthorn, C.; Charleson, A.W.; Allen, L.; Greene, M.; Jaiswal, Kishor; Silva, V.

    2013-01-01

    This report documents the development and applications of the Building Taxonomy for the Global Earthquake Model (GEM). The purpose of the GEM Building Taxonomy is to describe and classify buildings in a uniform manner as a key step towards assessing their seismic risk, Criteria for development of the GEM Building Taxonomy were that the Taxonomy be relevant to seismic performance of different construction types; be comprehensive yet simple; be collapsible; adhere to principles that are familiar to the range of users; and ultimately be extensible to non-buildings and other hazards. The taxonomy was developed in conjunction with other GEM researchers and builds on the knowledge base from other taxonomies, including the EERI and IAEE World Housing Encyclopedia, PAGER-STR, and HAZUS. The taxonomy is organized as a series of expandable tables, which contain information pertaining to various building attributes. Each attribute describes a specific characteristic of an individual building or a class of buildings that could potentially affect their seismic performance. The following 13 attributes have been included in the GEM Building Taxonomy Version 2.0 (v2.0): 1.) direction, 2.)material of the lateral load-resisting system, 3.) lateral load-resisting system, 4.) height, 5.) date of construction of retrofit, 6.) occupancy, 7.) building position within a block, 8.) shape of the building plan, 9.) structural irregularity, 10.) exterior walls, 11.) roof, 12.) floor, 13.) foundation system. The report illustrates the pratical use of the GEM Building Taxonomy by discussing example case studies, in which the building-specific characteristics are mapped directly using GEM taxonomic attributes and the corresponding taxonomic string is constructed for that building, with "/" slash marks separating attributes. For example, for the building shown to the right, the GEM Taxonomy string is: DX1/MUR+CLBRS+MOCL2/LWAL3/

  11. Data Analysis And Polarization Measurements With GEMS

    Science.gov (United States)

    Stohmayer, Tod

    2011-01-01

    The Gravity and Extreme Magnetism SMEX (GEMS) mission was selected by NASA for flight in 2014. GEMS will make the first sensitive survey of X-ray polarization across a wide range of source classes including black hole and neutron star binaries, AGN of different types, rotation and accretion-powered pulsars, magnetars, shell supernova remnants and pulsar wind nebulae. GEMS employs grazing-incidence foil mirrors and novel time-projection chamber (TPC) polarimeters leveraging the photoelectric effect. The GEMS detectors image the charge tracks of photoelectrons produced by 2 - 10 keV X-rays. The initial direction of the photoelectron is determined by the linear polarization of the photon. We present an overview of the data analysis challenges and methods for GEMS, including procedures for producing optimally filtered images of the charge tracks and estimating their initial directions. We illustrate our methods using laboratory measurements of polarized and unpolarized X-rays with flight-like detectors as well as from simulated tracks. We also present detailed simulations exploring the statistics of polarization measurements appropriate for GEMS, and make comparisons with previous work.

  12. Optical quality assurance of GEM foils

    International Nuclear Information System (INIS)

    An analysis software was developed for the high aspect ratio optical scanning system in the Detector Laboratory of the University of Helsinki and the Helsinki Institute of Physics. The system is used e.g. in the quality assurance of the GEM-TPC detectors being developed for the beam diagnostics system of the SuperFRS at future FAIR facility. The software was tested by analyzing five CERN standard GEM foils scanned with the optical scanning system. The measurement uncertainty of the diameter of the GEM holes and the pitch of the hole pattern was found to be 0.5μm and 0.3μm, respectively. The software design and the performance are discussed. The correlation between the GEM hole size distribution and the corresponding gain variation was studied by comparing them against a detailed gain mapping of a foil and a set of six lower precision control measurements. It can be seen that a qualitative estimation of the behavior of the local variation in gain across the GEM foil can be made based on the measured sizes of the outer and inner holes

  13. The GEM Detector projective alignment simulation system

    International Nuclear Information System (INIS)

    Precision position knowledge (< 25 microns RMS) of the GEM Detector muon system at the Superconducting Super Collider Laboratory (SSCL) is an important physics requirement necessary to minimize sagitta error in detecting and tracking high energy muons that are deflected by the magnetic field within the GEM Detector. To validate the concept of the sagitta correction function determined by projective alignment of the muon detectors (Cathode Strip Chambers or CSCs), the basis of the proposed GEM alignment scheme, a facility, called the ''Alignment Test Stand'' (ATS), is being constructed. This system simulates the environment that the CSCs and chamber alignment systems are expected to experience in the GEM Detector, albeit without the 0.8 T magnetic field and radiation environment. The ATS experimental program will allow systematic study and characterization of the projective alignment approach, as well as general mechanical engineering of muon chamber mounting concepts, positioning systems and study of the mechanical behavior of the proposed 6 layer CSCs. The ATS will consist of a stable local coordinate system in which mock-ups of muon chambers (i.e., non-working mechanical analogs, representing the three superlayers of a selected barrel and endcap alignment tower) are implemented, together with a sufficient number of alignment monitors to overdetermine the sagitta correction function, providing a self-consistency check. This paper describes the approach to be used for the alignment of the GEM muon system, the design of the ATS, and the experiments to be conducted using the ATS

  14. Simulation of the CMS GEM System

    CERN Document Server

    Sharma, Archie

    2015-01-01

    The new GE1/1 system of Gas Electron Multipiers (GEM) is going to be installed in the CMS detector in the forward region with $\\eta$ between 1.6 and 2.2 after the second long LHC shutdown. 36 super-chambers are planned to be installed in order to ensure the redundancy and robustness of the muon system in high-luminosity conditions at the LHC. A further extension to the GEM system is also considered. The simulation of the entire GEM system integrated in the common CMS reconstruction chain is a necessary part of the performed Monte Carlo studies. A dedicated parametric model based on the exhaustive standalone MC studies and experimental test beam results has been developed in order to simulate the response of the GEM system. The simulated digital readout signals are used to build the reconstructed hits in the detector planes. They have been included in the common CMS muon reconstruction algorithms. This contribution will present the developed simulation model and the importance of the gem system for the improve...

  15. Organische Leuchtdioden mit Polymeranoden

    OpenAIRE

    Fehse, Karsten

    2008-01-01

    In organischen Leuchtdioden (OLEDs) werden üblicherweise anorganische Materialien wie Indium-Zinn-Oxid (ITO) als transparente leitfähige Anoden verwendet. ITO besitzt allerdings eine geringe Austrittsarbeit und kann deshalb Löcher nicht effizient in organische Materialien injizieren. Weiterhin ist ITO eine Quelle von Indium- und Sauerstoff-Ionen, die in die organischen Materialien diffundieren und dort mit der Organik reagieren bzw. als effiziente Exzitonenvernichter agieren. Eine mögliche Al...

  16. Marketing mit Facebook

    OpenAIRE

    Nufer, Gerd; Vogt, Maximilian

    2013-01-01

    Die Integration von Facebook in ein bestehendes Marketingkonzept avanciert zunehmend zum Erfolgsfaktor innovativer Unternehmen. Das Marketing mit diesem sozialen Netzwerk ist dabei nicht auf die Kommunikationspolitik determiniert, sondern bietet die Möglichkeit, einen nachhaltigen Mehrwert im gesamten Marketing-Mix zu generieren. Vor diesem Hintergrund stellt Facebook aktuell das meist eingesetzte Social Marketing Instrument in Deutschland dar. Im Kontrast zum steigenden Bewusstsein der Vorte...

  17. Single electron multiplication distribution in GEM avalanches

    CERN Document Server

    Laszlo, Andras; Kiss, Gabor; Varga, Dezso

    2016-01-01

    In this paper measurement results and experimental methodology is presented on the determination of multiplication distributions of avalanches in GEM foils initiated by a single electron. The measurement relies on the amplification of photoelectrons by the GEM under study, which is subsequently amplified in an MWPC. The intrinsic detector resolution, namely the sigma over mean ratio of this distribution is also elaborated. Small gain dependence of the avalanche size is observed in the range of net effective gain of 15 to 100. The distribution has an exponentially decaying tail at large amplitudes, whereas the applied working gas is seen to have a well visible effect on the shape of the multiplication distribution at low amplitudes; or equivalently, the working gas has an influence on the intrinsic detector resolution of GEMs via suppression of the low amplitude responses. A sigma over mean ratio down to 0.75 was reached using neon based mixture, whereas other gases provided an intrinsic detector resolution cl...

  18. The GEMS-2 Seis Experiment

    Science.gov (United States)

    Mimoun, D.; de Raucourt, S.; Lognonne, P.; Giardini, D.; Christensen, U. R.; Gagnepain-Beyneix, J.; Pike, T.; Nebut, T.; Tillier, S.; Robert, O.; Gabsi, T.; Pot, O.; Lecomte, B.; Escande, N.; Mocquet, A.; Zweifel, P.; Mance, D.; Roll, R.; Bierwirth, M.

    2010-12-01

    of data will be made on the basis of raw compressed data, plus an excerpt of the high frequency events of the day. The proposed instrument has been developed up to PDR in the frame of the ExoMars Humbold payload. Most critical parts have been tested, including shock tests for pivot, electronics components and displacement sensors. TRL 6 is expected at the end of 2011. SEIS has been proposed onboard the GEMS Mission Proposal, submitted to NASA in the frame of the 2010 Discovery AO.

  19. Neutron beam imaging with GEM detectors

    International Nuclear Information System (INIS)

    Neutron GEM-based detectors represent a new frontier of devices in neutron physics applications where a very high neutron flux must be measured such as future fusion experiments (e.g. ITER Neutral beam Injector) and spallation sources (e.g. the European Spallation source). This kind of detectors can be properly adapted to be used both as beam monitors but also as neutron diffraction detectors that could represent a valid alternative for the 3He detectors replacement. Fast neutron GEM detectors (nGEM) feature a cathode composed by one layer of polyethylene and one of aluminium (neutron scattering on hydrogen generates protons that are detected in the gas) while thermal neutron GEM detectors (bGEM) are equipped with a borated aluminium cathode (charged particles are generated through the 10B(n,α)7Li reaction). GEM detectors can be realized in large area (1 m2) and their readout can be pixelated. Three different prototypes of nGEM and one prototype of bGEM detectors of different areas and equipped with different types of readout have been built and tested. All the detectors have been used to measure the fast and thermal neutron 2D beam image at the ISIS-VESUVIO beamline. The different kinds of readout patterns (different areas of the pixels) have been compared in similar conditions. All the detectors measured a width of the beam profile consitent with the expected one. The imaging property of each detector was then tested by inserting samples of different material and shape in the beam. All the samples were correctly reconstructed and the definition of the reconstruction depends on the type of readout anode. The fast neutron beam profile reconstruction was then compared to the one obtained by diamond detectors positioned on the same beamline while the thermal neutron one was compared to the imaged obtained by cadmium-coupled x-rays films. Also efficiency and the gamma background rejection have been determined. These prototypes represent the first step towards the

  20. GEM applications outside high energy physics

    CERN Document Server

    Duarte Pinto, Serge

    2013-01-01

    From its invention in 1997, the Gas Electron Multiplier has been applied in nuclear and high energy physics experiments. Over time however, other applications have also exploited the favorable properties of GEMs. The use of GEMs in these applications will be explained in principle and practice. This paper reviews applications in research, beam instrumentation and homeland security. The detectors described measure neutral radiations such as photons, x-rays, gamma rays and neutrons, as well as all kinds of charged radiation. This paper provides an overview of the still expanding range of possibilities of this versatile detector concept.

  1. Development of GEMs at Hampton University

    Science.gov (United States)

    Liyanage, Anusha; Kohl, Michael; MUSE Collaboration

    2015-10-01

    Two GEM telescopes each consisting of three 10×10 cm2 triple-GEM chambers 30-40 cm apart were built, tested and operated by the Hampton group. They are read out with APV25 frontend chips and FPGA based digitizing electronics developed by INFN Rome. The telescopes served as luminosity monitors for the OLYMPUS experiment at DESY in Hamburg, Germany, with positron and electron beams at 2 GeV. The telescopes have been recycled to serve as the beam particle tracker of the MUSE experiment at the Paul Scherrer Institute in Switzerland. In the identical configuration as in OLYMPUS, the telescope was limiting the accepted trigger rate in the test measurements. Therefore, an effort is ongoing to improve the GEM readout speed to meet the trigger rate at the design intensity of the MUSE experiment. Further, the Hampton group is responsible for the DarkLight phase-I lepton tracker which is in preparation at the low energy-recovering facility (LERF) at the Thomas Jefferson National Accelerator Facility in Newport News, USA, sponsored by the National Science Foundation through a Major Research Instrumentation (MRI) grant. The group's activities on GEM detector development will be summarized, and the achieved performance and the current effort to further improvements will be discussed.

  2. Performance of the GEM electromagnetic calorimeter

    International Nuclear Information System (INIS)

    The GEM EM calorimeter is optimized for the best energy, position, angular resolution and jet rejection. The detailed simulation results are presented. In the barrel with LKr, an energy resolution of about 6%/√ direct-sum 0.4%, pointing resolution of 40mrad/√E + 0.5mrad, and jet rejection of a factor of 5 are expected

  3. Ammoniakzersetzung mit salzmodifizierten Katalysatoren

    OpenAIRE

    Bajus, Stephanie

    2014-01-01

    Ziel dieser Arbeit war es, durch die Modifikation von Rutheniumkatalysatoren mit Salzen ein aktives System für die Ammoniakzersetzung zur Wasserstofffreisetzung zwischen 200 °C und 350 °C zu entwickeln. Die Modifikation sollte auf dem SCILL-Konzept aufbauen, bei dem in der ursprünglichen Variante eine ionische Flüssigkeit geträgert auf einem heterogenen Katalysator die katalytische Oberfläche modifizieren soll. Da ionische Flüssigkeiten nur bedingt thermisch stabil sind, sollte dieses Konzept...

  4. Study on Inclusions in Natural and Synthetic Gems

    Institute of Scientific and Technical Information of China (English)

    李兆麟

    2001-01-01

    The characteristics of inclusions in natural and synthetic gems are distinct owing to their different forming mechanisms and can be utilized to distinguish gems from different locali ties. In addition, intensive studies on inclusion characteristics of natural gems could identify their geographical origins and provide valuable information on gem synthesis. In this paper syn thetic gems (synthetic star-spangled sapphire and emerald) and natural gems from various loca tions including natural sapphire from Thailand and Australia, and natural aquamerine from Mu fushan, Hunan Province, and Ailaoshan, Yunnan Province, were selected for the comparative study of inclusions. Significant research results have been achieved, thus providing the impor tant basis for distinguishing natural from synthetic gems.

  5. Europa Imaging Highlights during GEM

    Science.gov (United States)

    1998-01-01

    During the two year Galileo Europa Mission (GEM), NASA's Galileo spacecraft will focus intensively on Jupiter's intriguing moon, Europa. This montage shows samples of some of the features that will be imaged during eight successive orbits. The images in this montage are in order of increasing orbit from the upper left (orbit 11) to the lower right (orbit 19).DESCRIPTIONS AND APPROXIMATE RESOLUTIONSTriple bands and dark spots1.6 kilometers/pixelConamara Chaos1.6 kilometers/pixelMannan'an Crater1.6 kilometers/ pixelCilix1.6 kilometers/pixelAgenor Linea and Thrace Macula2 kilometers/pixelSouth polar terrain2 kilometers/pixelRhadamanthys Linea1.6 kilometers/pixelEuropa plume search7 kilometers/pixel1. Triple bands and dark spots were the focus of some images from Galileo's eleventh orbit of Jupiter. Triple bands are multiple ridges with dark deposits along the outer margins. Some extend for thousands of kilometers across Europa's icy surface. They are cracks in the ice sheet and indicate the great stresses imposed on Europa by tides raised by Jupiter, as well as Europa's neighboring moons, Ganymede and Io. The dark spots or 'lenticulae' are spots of localized disruption.2. The Conamara Chaos region reveals icy plates which have broken up, moved, and rafted into new positions. This terrain suggests that liquid water or ductile ice was present near the surface. On Galileo's twelfth orbit of Jupiter, sections of this region with resolutions as high as 10 meters per picture element will be obtained.3. Mannann'an Crater is a feature newly discovered by Galileo in June 1996. Color and high resolution images (to 40 meters per picture element) from Galileo's fourteenth orbit of Jupiter will offer a close look at the crater and help characterize how impacts affect the icy surface of this moon.4. Cilix, a large mound about 1.5 kilometers high, is the center of Europa's coordinate system. Its concave top and what may be flow like features to the southwest of the mound are

  6. Thick GEM versus thin GEM in two-phase argon avalanche detectors

    CERN Document Server

    Bondar, A; Grebenuk, A; Pavlyuchenko, D; Tikhonov, Y; Breskin, Amos

    2008-01-01

    The performance of thick GEMs (THGEMs) was compared to that of thin GEMs in two-phase Ar avalanche detectors, in view of their potential application in coherent neutrino-nucleus scattering, dark-matter search and in other rare-event experiments. The detectors comprised a 1 cm thick liquid-Ar layer followed by either a double-THGEM or a triple-GEM multiplier, operated in the saturated vapor above the liquid phase. Three types of THGEMs were studied: those made of G10 and Kevlar and that with resistive electrodes (RETHGEM). Only the G10-made THGEM showed a stable performance in two-phase Ar with gains reaching 3000. Successful operation of two-phase Ar avalanche detectors with either thin- or thick-GEM multipliers was demonstrated at low detection thresholds, of 4 and 20 primary electrons respectively. Compared to the triple-GEM the double-THGEM multiplier yielded slower anode signals; this allowed applying a pulse-shape analysis to effectively reject noise signals. Noise rates of both multipliers were evaluate...

  7. Gas electron multipliers. Development of large area GEMS and spherical GEMS

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Serge Duarte

    2011-08-15

    Gaseous radiation detectors have been a crucial part of high-energy physics instrumentation since the 1960s, when the first multiwire proportional counters were built. In the 1990s the first micropattern gas detectors (MPGDS) saw the light; with sub-millimeter feature sizes these novel detectors were faster and more accurate than their predecessors. The gas electron multiplier (GEM) is one of the most successful of these technologies. It is a charge multiplication structure made from a copper clad polymer foil, pierced with a regular and dense pattern of holes. I describe the properties and the application of GEMs and GEM. detectors, and the research and development I have done on this technology. Two of the main objectives were the development of large area GEMs ({proportional_to}m{sup 2}) for particle physics experiments and GEMs with a spherical shape for X-ray or neutron diffraction detectors. Both have been realized, and the new techniques involved are finding their way to applications in research and industry. (orig.)

  8. GEM - A novel gaseous particle detector

    CERN Document Server

    Meinschad, T

    2005-01-01

    The work carried out within the framework of this Ph.D. deals with the construction of gaseous prototype detectors using Gas Electron Multiplier electrodes for the amplification of charges released by ionizing particles. The Gas Electron Multiplier (GEM) is a thin metal-clad polymer foil, etched with a high density of narrow holes, typically 50-100mm-2. On the application of a potential difference between the conductive top and bottom sides each hole acts as independent proportional counter. This new fast device permits to reach large amplification factors at high rates with a strong photon and ion-mediated feedback suppression due to the avalanche confinement in the GEM-holes. Here, in particular studies have been performed, which should prove, that the GEM-technology is applicable for an efficient measurement of single Cherenkov photons. These UV-photons can be detected in different ways. An elegant solution to develop large area RICH-detectors is to evaporate a pad-segmented readout-cathode of a multi-wire...

  9. Heavy metals in Ratnapura alluvial gem sediments, Sri Lanka

    Science.gov (United States)

    Vithanage, M. S.; Hettiarachchi, J. K.; Rajapaksha, A. U.; Wijesekara, H.; Hewawasam, T.

    2011-12-01

    The valuable gems in Sri Lanka are found from the sedimentary gem deposits in Ratnapura District, which are found as alluvial deposits some are about >50 m deep. Gem bearing gravel layer is taken out from the mine, washed by panning to recover the gem minerals in the heavy mineral fraction, is a common practice in the gem mining area. Gem bearing sediment layer is associated with different heavy minerals in which different trace metals as Co, Cr, Cu, Al, Zr, Pb and As also can be present. During panning, the sediment is washed away and the heavy metals attached to the sediments are released into the environment. Hence we studied the lability and bioavailability of arsenic and other heavy metals from the gem sediments. Sediment samples were collected from 15 small scale gem mines (3 soil layers- top, gem mineral layer and layer below gem bearing gravel layer), air dried and sieved to obtain 150 mg/kg), Cu (>150 mg/kg), Pb (>400 mg/kg), Zn (>600 mg/kg) and Co ions (>100 mg/kg). Arsenite in the gem sediments were low and recorded as Co>Zn>Mn>Ni>Cu>Pb. Sediments from few gem pits showed considerably high concentrations of metals analyzed. In some places Fe, Ni, Cu, Zn reported high in bioavailable fractions 70, 25, 20, 10 mg/kg respectively. Mobilization of these metals may increase due to changes in the pH and the presence of other ions in the environment. High concentrations of toxic metals in exchangeable and bioavailable fractions indicate the risk on plant and animals as well as the open water bodies and groundwater sources.

  10. Study of etching processes in the GEM detectors

    CERN Document Server

    Zavazieva, Darina

    2016-01-01

    Gaseous Electron Multiplier (GEM) detectors are known to operate stably at high gains and high particle fluxes. Though, at very high gains and fluxes it was observed that the insulating polyimide layer between the GEM electrodes gets etched, changing the original shape of the hole, and therefore varying the gain and the energy resolution of the detector. The idea of the project to observe degradation effect of the GEM foils during the Triple GEM detector operation in extreme conditions under X-ray radiation.

  11. Die Last mit der Lust

    Directory of Open Access Journals (Sweden)

    Lutz Sauerteig

    2004-03-01

    Full Text Available Robert Jütte legt mit Lust ohne Last eine umfassende, allgemeinverständliche und spannend zu lesende Geschichte der Empfängnisverhütung von der Antike bis in die unmittelbare Gegenwart vor.

  12. MIT-CSR XIS Project

    Science.gov (United States)

    1998-01-01

    This report outlines the proposers' progress toward MIT's contribution to the X-Ray Imaging Spectrometer (XIS) experiment on the Japanese ASTRO-E mission. The report discusses electrical system design, mechanical system design, and ground support equipment.

  13. Verbalsuffixe mit Liquida

    Directory of Open Access Journals (Sweden)

    Marina Zorman

    1995-12-01

    Full Text Available Der vorliegende Beitrag stellt eine Zusammenfassung bzw. vervollständigte Ver­ sion einiger Kapitel der Magisterarbeit der Autorin mit dem Titel Expressive Wort­ bildung beim Verb (Ältere, wahrscheinlich ererbte Kombinationen -V/C- + -r/l- - das Grundtypus -dr- - im Slowenischen dar. Die wesentlichen Erkenntnisse der Arbeit hinsichtlich der morphologischen und semantischen Gestalt derartiger Verben, ihrer dialektologischen Verbreitung und der Genese, Funktion und Austauschbarkeit dieser Suffixe sollen unter dem Titel "Ekspresivne glagolske pripone tipa -V/C + -r/l-" in den "Razprave XV II. razreda SAZU" (Dissertationes Classis II, XV. Ljubljana, Academia scientiarium et artium Slovenica (in Druck veröffentlicht werden, deshalb werden sie hier nur so weit aufgenommen, wie das für das Verständnis des behandelten Gegen­ stands unbedingt notwendig ist. Eingehender werden Fragen erortert, die im erwähnten Artikel nicht behandelt werden, die jedoch auch für andere Linguisten interessant sein könnten. So ist der vorliegende Beitrag in vier Teile gegliedert

  14. Rezidivmuster bei Kindern mit Medulloblastom

    OpenAIRE

    Blaßhofer, Sophia Katharina Charlotte

    2009-01-01

    Ziel der vorliegenden Arbeit ist es, das Rezidivmuster der Medulloblastome aufzuzeigen. Die Bedeutung prognostischer Faktoren, wie Therapie oder initiale Erkrankungsausdehnung soll im Zusammenhang mit dem Auftreten eines Rezidivs oder einer Progression näher untersucht werden. Es handelt sich um ein Patientenkollektiv von 40 Kindern mit einem Rezidiv eines Medulloblastoms. Die Patienten sind Teil des HIT 2000 Kollektivs, ein Patient war Teil der HIT ´91 Studie, 7 waren Beobachtungspatienten. ...

  15. Schädlingsbekämpfung im Vorrats- und Materialschutz mit Sulfurylfluorid

    OpenAIRE

    Reichmuth, Christoph; Klementz, Dagmar

    2008-01-01

    Seit mehreren Jahren ist Sulfurylfluorid (Sulfuryldifluorid, SF) als Schädlingsbekämpfungsmittel für den Materialschutz und den Vorratsschutz gegen Insekten gelistet. Insbesondere der Ersatz des ozonzerstörenden Brommethans wird in diesen Anwendungsgebieten überwiegend mit diesem Wirkstoff realisiert. Sulfurylfluorid gilt seit langer Zeit als ein bewährtes Begasungsmittel gegen Termiten in Holzhäusern in den Vereinigten Staaten. Als 2005 die Industrienationen gemäß den Beschlüssen des Montrea...

  16. Gas-gain study of standard CERN GEM and 400-μm-thick Thick GEM in low-pressure He/CO2 mixed gas

    International Nuclear Information System (INIS)

    We have evaluated and compared the performances of a 50-μm-thick CERN GEM and a 400-μm-thick Thick GEM in low-pressure He/CO2 (90%/10%) mixed gas. In particular, the empirical gas gains of the standard CERN GEM and the Thick GEM have been measured and investigated.

  17. MIT's interferometer CST testbed

    Science.gov (United States)

    Hyde, Tupper; Kim, Ed; Anderson, Eric; Blackwood, Gary; Lublin, Leonard

    1990-12-01

    The MIT Space Engineering Research Center (SERC) has developed a controlled structures technology (CST) testbed based on one design for a space-based optical interferometer. The role of the testbed is to provide a versatile platform for experimental investigation and discovery of CST approaches. In particular, it will serve as the focus for experimental verification of CSI methodologies and control strategies at SERC. The testbed program has an emphasis on experimental CST--incorporating a broad suite of actuators and sensors, active struts, system identification, passive damping, active mirror mounts, and precision component characterization. The SERC testbed represents a one-tenth scaled version of an optical interferometer concept based on an inherently rigid tetrahedral configuration with collecting apertures on one face. The testbed consists of six 3.5 meter long truss legs joined at four vertices and is suspended with attachment points at three vertices. Each aluminum leg has a 0.2 m by 0.2 m by 0.25 m triangular cross-section. The structure has a first flexible mode at 31 Hz and has over 50 global modes below 200 Hz. The stiff tetrahedral design differs from similar testbeds (such as the JPL Phase B) in that the structural topology is closed. The tetrahedral design minimizes structural deflections at the vertices (site of optical components for maximum baseline) resulting in reduced stroke requirements for isolation and pointing of optics. Typical total light path length stability goals are on the order of lambda/20, with a wavelength of light, lambda, of roughly 500 nanometers. It is expected that active structural control will be necessary to achieve this goal in the presence of disturbances.

  18. Analysis of Mechanical Properties for GEM Foil

    CERN Document Server

    Chin, Yuk Ming

    2016-01-01

    In view of new assembly technique of the GEM detector; in which three foils stack is stretched to get the uniform gaps among the foils. We studied the mechanical properties of the foil material. We conditioned the samples in different environments to make them extra dry and wet. As holes are the major source of the charge amplification their deformation can effect the detector performance. Therefore in our studies we also studied at which level of the stress the holes deformation is seen. These tensile and holes deformation studies can help to optimize the stress during detector assembly.

  19. The Ozone Layer. UNEP/GEMS Environment Library No. 2.

    Science.gov (United States)

    United Nations Environment Programme, Nairobi (Kenya).

    Since the United Nations Environment Program (UNEP) was created, more than a dozen years ago, public understanding of the environmental issues confronting our planet has increased enormously. The Global Environment Monitoring System (GEMS) has provided several environmental assessments. The aim of the UNEP/GEMS Environment Library is to provide…

  20. Google Books - Abzocken mit Rechtsbeistand

    OpenAIRE

    Gerhard Ruiss

    2010-01-01

    Wie sieht es eigentlich mit den Rechten bei "Google Books" aus? Vor rund einem Jahr wurden zum ersten Mal die Pläne von Google zur Veröffentlichung aller jemals erschienenen Bücher auf der Internetplattform "Google Book Search" bzw. mittlerweile "Google Bücher" auch außerhalb der USA bekannt. Bis zu diesem Zeitpunkt hielt man in den meisten anderen Ländern den Konflikt amerikanischer Autoren und Verlage mit dem US-Netzdienstleister "Google" über die Veröffentlichungsrechte für einen inner...

  1. Erfahrungen mit einem C-Pen

    OpenAIRE

    Ziegler, Christoph

    2002-01-01

    Gemeinsamer Workshop von Universitaetsrechenzentrum und Professur Rechnernetze und verteilte Systeme der Fakultaet fuer Informatik der TU Chemnitz. Der Vortrag beginnt mit der Vorstellung eines C-Pen. Erfahrungen mit der praktischen Anwendung eines solchen "Computer-Stiftes" bilden den Hauptteil.

  2. Gems of combinatorial optimization and graph algorithms

    CERN Document Server

    Skutella, Martin; Stiller, Sebastian; Wagner, Dorothea

    2015-01-01

    Are you looking for new lectures for your course on algorithms, combinatorial optimization, or algorithmic game theory?  Maybe you need a convenient source of relevant, current topics for a graduate student or advanced undergraduate student seminar?  Or perhaps you just want an enjoyable look at some beautiful mathematical and algorithmic results, ideas, proofs, concepts, and techniques in discrete mathematics and theoretical computer science?   Gems of Combinatorial Optimization and Graph Algorithms is a handpicked collection of up-to-date articles, carefully prepared by a select group of international experts, who have contributed some of their most mathematically or algorithmically elegant ideas.  Topics include longest tours and Steiner trees in geometric spaces, cartograms, resource buying games, congestion games, selfish routing, revenue equivalence and shortest paths, scheduling, linear structures in graphs, contraction hierarchies, budgeted matching problems, and motifs in networks.   This ...

  3. Forward GEM Tracker (FGT) at STAR

    Science.gov (United States)

    Surrow, Bernd

    2012-10-01

    As part of our program to understand the internal structure of the proton, we have and will continue mid-rapidity (-1anti-d quarks to the proton spin. The gluon spin contribution can be probed through di-jet measurements. The Forward GEM Tracker (FGT) at STAR will enhance the charged sign separation for high pT tracks in the pseudo-rapidity range of 1.0<η<2.0, and therefore allows an extension of W and di-jet measurements at forward pseudo-rapidity. We will present the status of the FGT assembly and completion along with projections for future W and di-jet measurements. We will discuss studies that explore the possibilities of using the FGT to reconstruct jets in the forward direction.

  4. Smugglers Eat Gem-Filled Condoms

    Institute of Scientific and Technical Information of China (English)

    宋毛林

    2003-01-01

    选注者言:阅读增加知识。此言不假。短短一文,我们得知,斯里兰卡这个美丽的岛国盛产宝石,尤其是兰宝石和红宝石。宝石,英语称precious stone又称gem(见标题),此外,海关的英语表达是customs,而不是custom。当然,还有一个重要的动词declare,当你以后经过海关检查时,海关人员问:Do you have anythingto declare?读了此文,你就不至于发呆吧?

  5. The AdMit Package

    NARCIS (Netherlands)

    D. David (David); L.F. Hoogerheide (Lennart); H.K. van Dijk (Herman)

    2008-01-01

    textabstractThis short note presents the R package AdMit which provides flexible functions to approximate a certain target distribution and it provides an efficient sample of random draws from it, given only a kernel of the target density function. The estimation procedure is fully automatic and thu

  6. Game Design Workshops mit Schulklassen

    OpenAIRE

    Christoph Kaindel

    2015-01-01

    Im Oktober 2015 hat Christoph Kaindel gemeinsam mit Claudia Bayerl fünf Game Design Workshops in der wienXtra spielebox durchgeführt. Dabei haben Schulklassen der 3. bis 8. Schulstufe teilgenommen, die Gruppengrößen lagen zwischen 17 und 24. Der Projektleiter berichtet ...

  7. Game Design Workshops mit Schulklassen

    Directory of Open Access Journals (Sweden)

    Christoph Kaindel

    2015-12-01

    Full Text Available Im Oktober 2015 hat Christoph Kaindel gemeinsam mit Claudia Bayerl fünf Game Design Workshops in der wienXtra spielebox durchgeführt. Dabei haben Schulklassen der 3. bis 8. Schulstufe teilgenommen, die Gruppengrößen lagen zwischen 17 und 24. Der Projektleiter berichtet ...

  8. Bestimmungsgründe von Veränderungen in der Wertschöpfungskette für Obst und Gemüse

    OpenAIRE

    Stolper, Oliver

    2015-01-01

    Die Wertschöpfungskette für frisches Obst und Gemüse in Deutschland hat sich in den letzten Jahrzehnten stark gewandelt. Die Konzentration im Einzelhandel, andere Konsumgewohnheiten und verbesserte Logistik haben Beschaffung und Angebot stark verändert. Daneben sind neue Stakeholder aufgetreten, die erfolgreich die Umsetzung ihrer Anliegen einforderten, was zu höheren Anforderungen an Produktsicherheit und Qualität führte. In der Wissenschaft beschäftigte man sich bislang nur wenig mit der We...

  9. Neutron beam monitor based on a boron-coated GEM

    Institute of Scientific and Technical Information of China (English)

    ZHOU Jian-Rong; LI Yi; SUN Zhi-Jia; LIU Ben; WANG Yan-Feng; YANG Gui-An; ZHOU Liang; XU Hong; DONG Jing; YANG Lei

    2011-01-01

    A new thermal neutron beam monitor with a Gas Electron Multiplier (GEM) is developed to meet the needs of the next generation of neutron facilities. A prototype chamber has been constructed with two 100 mm×100 mm GEM foils. Enriched boron-10 is coated on one surface of the aluminum cathode plate as the neutron convertor. 96 channel pads with an area of 8 mm×8 mm each are used for fast signal readout.In order to study the basic characteristics of a boron-coated GEM, several irradiation tests were carried out with α source 239pu and neutron source 241Am(Be). The signal induced by the neutron source has a high signal-to-noise ratio. A clear image obtained from α source 239pu is presented, which shows that the neutron beam monitor based on a boron-coated GEM has a good two-dimensional imaging ability.

  10. Turnover Rate Simulation Using GEM Detector on Neutron Radiography

    Institute of Scientific and Technical Information of China (English)

    SHAN; Chao; LI; Xiao-mei; HU; Shou-yang; ZHOU; Jing; JIAN; Si-yu; BAI; Xin-zhan; YE; Li; ZHOU; Shu-hua

    2012-01-01

    <正>With the advantages of high counting rate, high resolution ratio and high compatibility, GEM (Gas Electron Multiplier) detector has becoming the hot topic in the field of gas detector. Using GEM on neutron radiography, we need a suitable neutron converter. By the action on the converter and ingoing neutron, the outgoing particles could be an alpha or proton, which are charged particles. The charged

  11. Development of Tracking Detectors with industrially produced GEM Foils

    CERN Document Server

    Simon, F; Becker, U; Burns, L; Crary, D; Kearney, K; Keeler, G; Majka, R; Paton, K; Saini, G; Smirnov, N; Surrow, B; Woody, C

    2007-01-01

    The planned tracking upgrade of the STAR experiment at RHIC includes a large-area GEM tracker used to determine the charge sign of electrons and positrons produced from W+(-) decays. For such a large-scale project commercial availability of GEM foils is necessary. We report first results obtained with a triple GEM detector using GEM foils produced by Tech-Etch Inc. of Plymouth, MA, USA. Measurements of gain uniformity, long-term stability as well as measurements of the energy resolution for X-Rays are compared to results obtained with an identical detector using GEM foils produced at CERN. A quality assurance procedure based on optical tests using an automated high-resolution scanner has been established, allowing a study of the correlation of the observed behavior of the detector and the geometrical properties of the GEM foils. Detectors based on Tech-Etch and CERN produced foils both show good uniformity of the gain over the active area and stable gain after an initial charge-up period, making them well sui...

  12. Research and Development of Commercially Manufactured Large GEM Foils

    CERN Document Server

    Posik, M

    2014-01-01

    The recently completed Forward GEM Tracker (FGT) of the STAR experiment at RHIC took advantage of commercially produced GEM foils based on double-mask chemical etching techniques. With future experiments proposing detectors that utilize very large-area GEM foils, there is a need for commercially available GEM foils. Double-mask etching techniques pose a clear limitation in the maximum size. In contrast, single-mask techniques developed at CERN would allow one to overcome those limitations. We report on results obtained using 10 $\\times$ 10 cm$^2$ and 40$\\times$40 cm$^2$ GEM foils produced by Tech-Etch Inc. of Plymouth, MA, USA using single-mask techniques and thus the beginning for large GEM foil production on a commercial basis. A quality assurance procedure has been established through electrical and optical analyses via leakage current measurements and an automated high-resolution CCD scanner. The Tech-Etch foils show excellent electrical properties with leakage currents typically measured below 1 nA. The ...

  13. 3D Observation of GEMS by Electron Tomography

    Science.gov (United States)

    Matsuno, Junya; Miyake, Akira; Tsuchiyama, Akira; Nakamura-Messenger, Keiko; Messenger, Scott

    2014-01-01

    Amorphous silicates in chondritic porous interplanetary dust particles (CP-IDPs) coming from comets are dominated by glass with embedded metal and sulfides (GEMS). GEMS grains are submicron-sized rounded objects (typically 100-500) nm in diameter) with anaometer-sized (10-50 nm) Fe-Ni metal and sulfide grains embedded in an amorphous silicate matrix. Several formation processes for GEMS grains have been proposed so far, but these models are still being debated [2-5]. Bradley et al. proposed that GEMS grains are interstellar silicate dust that survived various metamorphism or alteration processes in the protoplanetary disk and that they are amorphiation products of crystalline silicates in the interstellar medium by sputter-deposition of cosmic ray irradiation, similar to space weathering [2,4]. This consideration is based on the observation of nano-sized crystals (approximately 10 nm) called relict grains in GEMS grains and their shapes are pseudomorphs to the host GEMS grains. On the other hand, Keller and Messenger proposed that most GEMS formed in the protoplanetary disk as condensates from high temperature gas [3,5]. This model is based on the fact that most GEMS grains have solar isotopic compositions and have extremely heterogeneous and non-solar elemental compositions. Keller and Messenger (2011) also reported that amorphous silicates in GEMS grains are surrounded by sulfide grains, which formed as sulfidization of metallic iron grains located on the GEMS surface. The previous studies were performed with 2D observation by using transmission electron microscopy (TEM) or scanning TEM (STEM). In order to understand the structure of GEMS grains described above more clearly, we observed 3D structure of GEMS grains by electron tomography using a TEM/STEM (JEM-2100F, JEOL) at Kyoto University. Electron tomography gives not only 3D structures but also gives higher spatial resolution (approximately a few nm) than that in conventional 2D image, which is restricted by

  14. Tragverhalten von Textilbeton mit Kurzfasern

    OpenAIRE

    Brameshuber, Wolfgang; Hinzen, Marcus

    2011-01-01

    Das Tragverhalten von Textilbeton kann durch den Einsatz von Kurzfasern erheblich verbessert werden. Untersuchungen zeigen eine Anhebung der Erstrisslast, ein dehnungsverfestigendes Verhalten, eine Verfeinerung des Rissbildes sowie eine Anhebung der maximalen Tragfähigkeit. Unklar sind bisher noch die genauen Mechanismen, die eine gezielte Einstellung des Tragverhaltens ermöglichen. Der Beitrag fasst die Untersuchungen zu den einzelnen Bereichen der Spannungs- ehnungslinie von Textilbeton mit...

  15. Befestigungen mit Verbundankern. Teil 3

    OpenAIRE

    Eligehausen, Rolf; Mallée, Rainer; Rehm, Gallus

    1984-01-01

    Seit 1975 wurden Verbundankersysteme verschiedener Firmen bauaufsichtlich zugelassen, wobei die Systeme hinsichtlich der Zusammensetzung des Mörtels praktisch identisch sind. Diese Zulassungsbescheide regelten die Verwendung von Einzelankern sowie Ankerpaaren mit Ankern in der aus Lastspannungen erzeugten Druckzone von Beton- und Stahlbetonbauteilen. Die Anwendungsbedingungen wurden u. a. aus den beschriebenen Versuchen abgeleitet und sind ausführlich erläutert. Weitere wichtige Informationen...

  16. Befestigungen mit Verbundankern. Teil 2

    OpenAIRE

    Eligehausen, Rolf; Mallée, Rainer; Rehm, Gallus

    1984-01-01

    Seit 1975 wurden Verbundankersysteme verschiedener Firmen bauaufsichtlich zugelassen, wobei die Systeme hinsichtlich der Zusammensetzung des Mörtels praktisch identisch sind. Diese Zulassungsbescheide regelten die Verwendung von Einzelankern sowie Ankerpaaren mit Ankern in der aus Lastspannungen erzeugten Druckzone von Beton- und Stahlbetonbauteilen. Die Anwendungsbedingungen wurden u. a. aus den beschriebenen Versuchen abgeleitet und sind ausführlich erläutert. Weitere wichtige Informationen...

  17. Befestigungen mit Verbundankern. [Teil 1

    OpenAIRE

    Eligehausen, Rolf; Mallée, Rainer; Rehm, Gallus

    1984-01-01

    Seit 1975 wurden Verbundankersysteme verschiedener Firmen bauaufsichtlich zugelassen, wobei die Systeme hinsichtlich der Zusammensetzung des Mörtels praktisch identisch sind. Diese Zulassungsbescheide regelten die Verwendung von Einzelankern sowie Ankerpaaren mit Ankern in der aus Lastspannungen erzeugten Druckzone von Beton- und Stahlbetonbauteilen. Die Anwendungsbedingungen wurden u. a. aus den beschriebenen Versuchen abgeleitet und sind ausführlich erläutert. Weitere wichtige Informationen...

  18. Relazione tecnica su DSpace (MIT)

    OpenAIRE

    De Robbio, Antonella

    2002-01-01

    This report presents Dspace that is a product realized in 2000 between Libraries of MIT (Massachussetts Institute Technology) and Hewlett-Packard Company relating to building a repository. It is able to support long-term memory, capturing and archiving of scholastic documents, realized from all MIT’s departments and free access by WWW, too. Furthermore, Dspace supports distribution and self-preservation of a different kinds of materials such as texts, videos, sounds, pictures, software and...

  19. MitWirkung - Zukunft gestalten

    OpenAIRE

    Säck-da Silva, Sabine

    2009-01-01

    Die Diskussion in den Planungswissenschaften beschreibt den Paradigmenwechsel vom so genannten DEAD-Model (Decide-Announce-Defend) zum Tripple-D-Model (Dialogue-Decide-Deliver) und beschäftigt sich intensiv mit dem Thema Governance. Komplexe Planungsaufgaben brauchen eine Vielfalt an Lösungsideen unterschiedlicher gesellschaftlicher Gruppen. Planung verfolgt u. a. die Umsetzung der Ziele einer nachhaltigen Entwicklung, die die Einbeziehung der Öffentlichkeit (Zivilgesellschaft, Unternehmen un...

  20. Google Books - Abzocken mit Rechtsbeistand

    Directory of Open Access Journals (Sweden)

    Gerhard Ruiss

    2010-03-01

    Full Text Available Wie sieht es eigentlich mit den Rechten bei "Google Books" aus? Vor rund einem Jahr wurden zum ersten Mal die Pläne von Google zur Veröffentlichung aller jemals erschienenen Bücher auf der Internetplattform "Google Book Search" bzw. mittlerweile "Google Bücher" auch außerhalb der USA bekannt. Bis zu diesem Zeitpunkt hielt man in den meisten anderen Ländern den Konflikt amerikanischer Autoren und Verlage mit dem US-Netzdienstleister "Google" über die Veröffentlichungsrechte für einen inneramerikanischen Streit. Erst durch die gerichtliche Anordnung des mit der Streitbeilegung beschäftigten New Yorker Richters Denny Chin zur weltweiten Bekanntmachung der konkreten Pläne von Google im Februar 2009 zeigte sich das gesamte Ausmaß der Absichten Googles. Google hatte in einem gerichtlichen Vergleichsdokument ("Google Book Settlement", das von Chin genehmigt werden sollte, sämtliche im Buchhandel erhältliche und in Bibliotheken archivierte Buchtitel weltweit aufgelistet, um sie nach gerichtlicher Genehmigung im Volltext in seinem Büchersuchdienst abrufbar zu machen. Inklusive weiterer Veröffentlichungen und Verbreitungen der Bücher zu seinem Nutzen und Gewinn wie u.a. durch Downloads, Print-On-Demand-Ausgaben, E-Books, Datenbank-Einspeisungen u.v.a.m.

  1. Aktuelles aus der Forschung mit menschlichen embryonalen Stammzellen (Mit dem Jahresbericht 2004 der Zentralen Ethikkommission für Stammzellenforschung

    Directory of Open Access Journals (Sweden)

    Beier HM

    2005-01-01

    Full Text Available Im internationalen Diskurs über die Forschung mit menschlichen embryonalen Stammzellen und die Perspektiven, regenerative Therapien zu entwickeln, fanden sich in jüngster Zeit bemerkenswerte Beiträge, auf die wir hier zurückgreifen. In den aufstrebenden Forschungsnationen Südkorea, Taiwan, Singapur und China läuft ein enormer Wettbewerb um die umfangreichsten Forschungsressourcen und die Führung in der embryonalen Stammzellforschung ab. In Europa und in den USA investieren Wissenschaftler Zeit, Forschungsmittel und intellektuelle Kapazität in die Suche nach Wegen, humane embryonale Stammzellen herzustellen, ohne menschliche Eizellen und Embryonen für diese Verfahren opfern zu müssen. In Deutschland finden solche Bemühungen ein positives Echo, weil das Gesetz es verbietet, embryonale Stammzellen aus verwaisten Blastozysten, sog. überzähligen Embryonen, herzustellen. Dem Stammzellgesetz gemäß kann in Deutschland nur unter Ausnahmebedingungen an menschlichen embryonalen Stammzellen geforscht werden. Wissenschaftler dürfen nach Prüfung und Genehmigung eines speziellen Projektantrages durch das Robert-Koch-Institut menschliche embryonale Stammzell-Linien von bestimmten, lizensierten, ausländischen Herstellern importieren. Allerdings müssen diese Zell-Linien vor dem Stichtag, dem 1.1.2002, hergestellt worden sein. Die Zentrale Ethik-Kommission für Stammzellenforschung (ZES, die das Robert-Koch-Institut im Auftrag der Bundesregierung berät, berichtet jedes Jahr über ihre Arbeit. Im zweiten Teil dieses Artikels wird mit freundlicher Genehmigung des Bundesministeriums für Gesundheit und Soziale Sicherheit der ZES-Jahresbericht 2004 veröffentlicht.

  2. Geothermal elastometric materials (GEM) program. Final report

    Energy Technology Data Exchange (ETDEWEB)

    Hirasuna, A.R.; Bilyeu, G.D.; Davis, D.L.; Sedwick, R.A.; Stephens, C.A.; Veal, G.R.

    1979-07-01

    The primary program objective, to develop a geothermal packer elastomer to withstand 260/sup 0/C (500/sup 0/F) geothermal brine with 300 ppM H/sub 2/S, 1000 ppM CO/sub 2/, 25,000 ppM NaCl in aqueous solution for 24 hours, was successfully accomplished. In fact the requirement for one elastomer was exceeded, compounds from four elastomeric polymer systems were successfully developed to meet the GEM requirements providing good flexibility for various situations. Several secondary spin-offs also resulted. The compounds were developed for the casing packer seal application and it was demonstrated that these compounds are directly applicable to the static O-ring and other elastomer applications in similarly unusually severe environments. There is also indication based on drill bits seal tests that the basic compounds will be adaptable to high-temperature dynamic seal applications. Another secondary spin-off is a different conceptual approach to the thermal casing packer problem. This approach concentrates on minimizing the stresses subjected on the sealing element. Since it is fundamentally different, it has a good chance of advancing thermal packer capability in a revolutionary manner as opposed to an evolutionary manner.

  3. Vergleichende Untersuchungen zur Wasseraufbereitung mit getauchten Membranen

    OpenAIRE

    Seidel, Tosca

    2004-01-01

    Die vorliegende Ausgabe beschäftigt sich mit dem Thema vergleichende Untersuchungen zur Wasseraufbereitung mit getauchten Membranen. Es werden drei Verfahren zur Aufbereitung von Oberflächenwasser zu Trinkwasser unter technischen, ökonomischen und ökologischen Gesichtspunkten verglichen. Das Verfahren der Ultrafiltration mit getauchten Membranen wurde dazu für drei Monate in einem kleintechnischen Pilotversuch an der Aare, Schweiz, getestet und hinsichtlich der Filtrationsleistung unter Varia...

  4. Konzepte zur rekonstruktiven Bildgebung mit hochfrequentem Ultraschall

    OpenAIRE

    Opretzka, Jörn

    2011-01-01

    Diese Arbeit beschäftigt sich mit Verfahren, mit denen die Bildgebungseigenschaften hochfrequenter Ultraschall- Abbildungssysteme auf Basis sphärisch fokussierender Ultraschallwandler verbessert werden können. Bei der Technik des Limited Angle Spatial Compounding werden aus verschiedenen Blickwinkeln aufgenommene Echosignale nach Demodulation überlagert. Mittels der neuartigen Fokussierungstechnik PBF-SAFT werden die Echosignale zunächst mit dem Ziel einer tiefenunabhängigen Auflö...

  5. The Bisa GEM-Mars GCM

    Science.gov (United States)

    Neary, Lori; Daerden, Frank

    2013-04-01

    GEM-Mars is a three-dimensional general circulation model of the Mars atmosphere extending from the surface to approximately 170 km based on the latest version of the GEM (Global Environmental Mesoscale) model, the operational data assimilation and weather forecasting system for Canada [Côté et al., 1998]. The dynamical core is an implicit two-time-level semi-Lagrangian scheme on an Arakawa C-grid with a terrain-following, log-hydrostatic-pressure vertical coordinate discretized on a Charney-Phillips grid. The model has both a hydrostatic and non-hydrostatic formulation, providing a single platform for simulations on a variety of horizontal scales. The model code is fully parallelized using OMP and MPI. The GCM includes the relevant physical processes such as CO2 condensation, planetary boundary layer mixing, gravity wave drag and surface parameterizations. A simple water cycle, basic gas-phase chemistry and passive tracers are also included in the model. Because of the vertical extent of the model, UV heating, non-LTE effects and molecular diffusion are also included. Dust is prescribed using the MGS scenario for total opacities and a Conrath profile shape. In the dust radiative transfer code, dust optical properties are based on the Wolff et al [2006, 2009] data. Temperatures in the lower and middle atmosphere have been evaluated using TES [Smith, 2004] and MCS [Kleinbohl et al. 2009] data. Winds and atmospheric circulation (mass stream functions) have been compared with the literature and show a good correspondence to other Mars GCMs. In parallel, active lifting and settling of size-distributed dust has also been implemented. The soil model has been improved to better match surface and near-surface temperatures from the Viking Landers, Phoenix [Davy et al. 2010], and TES. Near-surface winds and friction velocities have been compared with the literature and show reasonable performance. Condensation of CO2 in surface ice has been validated using CO2 ice mass

  6. The Forward GEM Tracker of STAR at RHIC

    CERN Document Server

    Simon, F; Fatemi, R; Hasell, D; Kelsey, J; Majka, R; Page, B; Plesko, M; Underwood, D; Smirnov, N; Sowinski, J; Spinka, H; Surrow, B; Visser, G

    2008-01-01

    The STAR experiment at the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory (BNL) is in the process of designing and constructing a forward tracking system based on triple GEM technology. This upgrade is necessary to give STAR the capability to reconstruct and identify the charge sign of W bosons over an extended rapidity range through their leptonic decay mode into an electron (positron) and a neutrino. This will allow a detailed study of the flavor-separated spin structure of the proton in polarized p + p collisions uniquely available at RHIC. The Forward GEM Tracker FGT will consist of six triple GEM disks with an outer radius of ~39 cm and an inner radius of ~10.5 cm, arranged along the beam pipe, covering the pseudo-rapidity range from 1.0 to 2.0 over a wide range of collision vertices. The GEM foils will be produced by Tech-Etch, Inc. Beam tests with test detectors using 10 cm x 10 cm Tech-Etch GEM foils and a two dimensional orthogonal strip readout have demonstrated a spatial r...

  7. Innovative genomic collaboration using the GENESIS (GEM.app) platform.

    Science.gov (United States)

    Gonzalez, Michael; Falk, Marni J; Gai, Xiaowu; Postrel, Richard; Schüle, Rebecca; Zuchner, Stephan

    2015-10-01

    Next-generation sequencing has led to an unparalleled pace of Mendelian disease gene discovery in recent years. To address the challenges of analysis and sharing of large datasets, we had previously introduced the collaborative web-based GEM.app software [Gonzalez et al., ]. Here, we are presenting the results of using GEM.app over nearly 3 years and introducing the next generation of this platform. First, GEM.app has been renamed to GENESIS since it is now part of "The Genesis Project" (501c3), a not-for-profit foundation that is committed to providing the best technology to enable research scientists and to connecting patients and clinicians to genomic information. Second, GENESIS (GEM.app) has grown to nearly 600 registered users from 44 countries, who have collectively achieved 62 gene identifications or published studies that have expanded phenotype/genotype correlations. Our concept of user-driven data sharing and matchmaking is now the main cause for gene discoveries within GENESIS. In many of these findings, researchers from across the globe have been connected, which gave rise to the genetic evidence needed to successfully pinpoint-specific gene mutations that explained patients' disease. Here, we present an overview of the various novel insights that have been made possible through the data-sharing capabilities of GENESIS/GEM.app. PMID:26173844

  8. Testbeam results for full-size triple GEM detectors

    CERN Document Server

    Sharma, Ram Krishna

    2015-01-01

    The High Luminosity LHC (HL-LHC) will provide exceptional instantaneous and integrated luminosities. The forward region $\\mid \\eta \\mid \\ge 1.5$ of the Compact Muon Solenoid (CMS) detector will face extremely high particle rates in tens of $KHz/cm^2$ and hence it will affect the momentum resolution and longevity of the muon detectors. To overcome these issues the CMS-GEM collaboration has proposed to install new large size rate capable Triple Gas Electron Multiplier (GEM) detectors in the forward region of CMS muon system. The first set of Triple GEM detectors will be installed in the GE1/1 region $(1.5 \\le \\eta \\le 2.2)$ of muon endcap during the long shutdown 2 of the LHC. Towards this goal, full size CMS Triple GEM prototype chambers have been fabricated and put under the test beam at the CERN SPS test beam facility. The GEM detectors were operated with two gas mixtures $Ar/CO_2$ (70/30) and $Ar/CO_2/CF_4$ (40/15/45). In 2014, good quality data was collected during test beam campaigns. In this paper, th...

  9. Transacylierungen mit Acylderivaten des 4-Pyridons

    OpenAIRE

    Effenberger, Franz; Bessey, Eberhard

    1980-01-01

    Mit N-Acyl-4-pyridonen (2a, b) sowie mit 4-(Benzoyloxy)pyridin (3a) werden in Methylenchlorid oder Chloroform aliphatische und aromatische Amine sowie Thiole glatt zu den Amiden (4 - 6) und Thioestern (7, 8) acyliert. Primäre und sekundäre Alkohole reagieren langsamer, tert-Butylalkohol nur noch mit 3a unter Basenkatalyse sowie mit den reaktiveren N-(Trihalogenacetyl)-4-pyridonen 3b, c zu den tert-Butylestern 12. N-Acetyl-4-pyridon (2a) besitzt ein deutlich höheres Acylierungspotential als N-...

  10. GEM400: A front-end chip based on capacitor-switch array for pixel-based GEM detector

    International Nuclear Information System (INIS)

    The upgrade of Beijing Synchrotron Radiation Facility (BSRF) needs two-dimensional position-sensitive detection equipment to improve the experimental performance. Gas Electron Multiplier (GEM) detector, in particular, pixel-based GEM detector has good application prospects in the domain of synchrotron radiation. The read-out of larger scale pixel-based GEM detector is difficult for the high density of the pixels (PAD for collecting electrons). In order to reduce the number of cables, this paper presents a read-out scheme for pixel-based GEM detector, which is based on System-in-Package technology and ASIC technology. We proposed a circuit structure based on capacitor switch array circuit, and design a chip GEM400, which is a 400 channels ASIC. The proposed circuit can achieve good stability and low power dissipation. The chip is implemented in a 0.35μm CMOS process. The basic functional circuitry in ths chip includes analog switch, analog buffer, voltage amplifier, bandgap and control logic block, and the layout of this chip takes 5mm × 5mm area. The simulation results show that the chip can allow the maximum amount of input charge 70pC on the condition of 100pF external integrator capacitor. Besides, the chip has good channel uniformity (INL is better than 0.1%) and lower power dissipation.

  11. Triple GEM Detectors for the Forward Tracker in STAR

    CERN Document Server

    Simon, Frank; Kohl, Michael; Majka, Richard; Plesko, Miroslav; Underwood, David; Sakuma, Tai; Smirnov, Nikolai; Spinka, Harold; Surrow, Bernd

    2007-01-01

    Future measurements of the flavor-separated spin structure of the proton via parity-violating W boson production at RHIC require an upgrade of the forward tracking system of the STAR detector. This upgrade will allow the reconstruction of the charge sign of electrons and positrons produced from decaying W bosons. A design based on six large area triple GEM disks using GEM foils produced by Tech-Etch Inc. has emerged as a cost-effective solution to provide the necessary tracking precision. We report first results from a beam test of three test detectors using Tech-Etch produced GEM foils and a laser etched two dimensional strip readout. The detectors show good operational stability, high efficiency and a spacial resolution of around 70 um or better, exceeding the requirements for the forward tracking upgrade. The influence of the angle of incidence of the particles on the spatial resolution of the detectors has also been studied in detail.

  12. Readout of TPC Tracking Chambers with GEMs and Pixel Chip

    Energy Technology Data Exchange (ETDEWEB)

    Kadyk, John; Kim, T.; Freytsis, M.; Button-Shafer, J.; Kadyk, J.; Vahsen, S.E.; Wenzel, W.A.

    2007-12-21

    Two layers of GEMs and the ATLAS Pixel Chip, FEI3, have been combined and tested as a prototype for Time Projection Chamber (TPC) readout at the International Linear Collider (ILC). The double-layer GEM system amplifies charge with gain sufficient to detect all track ionization. The suitability of three gas mixtures for this application was investigated, and gain measurements are presented. A large sample of cosmic ray tracks was reconstructed in 3D by using the simultaneous timing and 2D spatial information from the pixel chip. The chip provides pixel charge measurement as well as timing. These results demonstrate that a double GEM and pixel combination, with a suitably modified pixel ASIC, could meet the stringent readout requirements of the ILC.

  13. Gaseous Electron Multiplier (GEM), foil holes deformation studies

    CERN Document Server

    Suhaj, Adam; CERN. Geneva. PH Department

    2015-01-01

    GEM detectors play an important role in the upcoming high-luminosity LHC upgrade in 2018 where they will be exposed to high doses of radiation in the muon endcap region. A series of tensile tests were performed on neutron irradiated and non-irradiated GEM foils where the shape of the holes was thoroughly examined. It was found that the GEM foil does not deform much at lower loads but the deformation gets exponentially bigger after applying more than a 60 N force. Both sets of samples behaved similarly at lower loads up to 40 N after which the holes of the irradiated samples started to deform more rapidly than the non-irradiated ones. The failure point of the non-irradiated samples occurred consistently at around 135 N while the irradiated samples experienced failure at around 85 N with two outliers failing at 120 and 135 N.

  14. R&D on the Gem Readout of the Tesla TPC

    OpenAIRE

    Hamann, Markus

    2003-01-01

    Ongoing studies for the TESLA TPC with GEM readout at DESY/Hamburg University are presented. They include basic GEM performances, tracking and the determination of the resolution using different pad sizes and geometries as well as ion feedback measurements.

  15. Harnack Inequality and Applications for Infinite-Dimensional GEM Processes

    OpenAIRE

    Feng, Shui; Wang, Feng-Yu

    2014-01-01

    The dimension-free Harnack inequality and uniform heat kernel upper/lower bounds are derived for a class of infinite-dimensional GEM processes, which was introduced in \\cite{FW} to simulate the two-parameter GEM distributions. In particular, the associated Dirichlet form satisfies the super log-Sobolev inequality which strengthens the log-Sobolev inequality derived in \\cite{FW}. To prove the main results, explicit Harnack inequality and super Poincar\\'e inequality are established for the one-...

  16. Desinfektion mit hydrodynamischer Kavitation und Chlordioxid

    OpenAIRE

    Maslak, Dominik

    2010-01-01

    Die Kombination von hydrodynamisch erzeugter Kavitation mit Desinfektionsmitteln ist ein neuer Ansatz zur effektiveren Wasserentkeimung. Zur Erzeugung oszillierender Kavitationsblasen wurde ein neuer Kavitationsreaktor (Mikrogitter mit Nachlaufdüse) entwickelt und reaktionstechnisch charakterisiert. Gegenüber der üblich verwendeten Lochblende wird hiermit besonders der Energieeintrag reduziert. Es konnte am Beispiel des Bakteriums Escherichia coli gezeigt werden, dass bei Kombination von hydr...

  17. Positive Werkzeuge mit hohem IQ

    Science.gov (United States)

    Luik, Matthias

    Fräsen ist ein Verfahren, auf welches im modernen Produktionsprozess nicht verzichtet werden kann. Dabei stellt die zunehmende Komplexität der zu fertigenden Bauteile ganz neue Herausforderungen an ein Werkzeug. Konnten früher Bauteile nur mit hohem Aufwand durch Erodieren oder Außenräumen hergestellt werden, müssen heute bereits Fräswerkzeuge für solche Bearbeitungsaufgaben aus Zeitund Kostengründen eingesetzt werden. Dies führt dazu, dass viele Bauteile heute in einer Aufspannung bearbeitbar sind, welche früher nur durch mehrmaliges Umspannen erzeugt werden konnten. Um Bearbeitungszeiten und -kosten dabei gering zu halten, müssen aber dennoch universelle Werkzeuge eingesetzt werden, welche für verschiedenste Bearbeitungsaufgaben ausgelegt sind.

  18. The Gravity and Extreme Magnetism Small Explorer (GEMS)

    Science.gov (United States)

    Kallman, T. R.

    2011-01-01

    The Gravity and Extreme Magnetism Small Explorer (GEMS) was selected by NASA for flight in 2014 to make a sensitive search for X-ray polarization from a wide set of source classes, including stellar black holes, Seyfert galaxies and quasars, blazars, rotation and accretion-powered pulsars, magnetars, shell supernova remnants and pulsar wind nebulae. Among the primary scientific objectives are determining the effects of the spin of black holes and the geometry of supermassive black hole accretion, determining the configurations of the magnetic fields and the X-ray emission of magnetars, and determining the magnetic structure of the supernova shocks in which cosmic rays are accelerated. GEMS will observe 23 targets during a 16 month prime mission, in observations that will be able to reach predicted levels of polarization. The mission can be extended to provide a guest observer phase. The GEMS instrument has time projection chamber polarimeters with high 2-10 keV efficiency at the focus of thin foil mirrors. The 4.5 m focal length mirrors will be deployed on an extended boom. The spacecraft with the instrument is rotated with a period of about 10 minutes to enable measurement and correction of systematic errors. A small Bragg reflection soft X-ray experiment takes advantage of this rotation to obtain a measurement at 0.5 keV. The design of the GEMS instrument and the mission, the expected performance and the planned science program will be discussed.

  19. MicroGEMS employs the power of the processor

    International Nuclear Information System (INIS)

    The MicroGEMS dosimetric stations (Great Britain), designed for the control of γ-radiation intensity in the areas of location of NPP and other nuclear industry enterprises, are described. The stations are adapted for the creation of annular monitoring systems controlled by computers from a single centre over telemetric communication lines

  20. The Greenhouse Gases. UNEP/GEMS Environment Library No. 1.

    Science.gov (United States)

    United Nations Environment Programme, Nairobi (Kenya).

    Since the United Nations Environment Program (UNEP) was created, more than a dozen years ago, public understanding of the environmental issues confronting our planet has increased enormously. The Global Environment Monitoring System (GEMS) has provided several environmental assessments including urban air pollution, climate modification,…

  1. CMS Technical Design Report for the Muon Endcap GEM Upgrade

    CERN Document Server

    Colaleo, A; Sharma, A; Tytgat, M; CERN. Geneva. The LHC experiments Committee; LHCC

    2015-01-01

    This report describes both the technical design and the expected performance of the Phase-II upgrade, using Gas Electron Multiplier (GEM) detectors, of the first endcap station of the CMS muon system. The upgrade is targeted for the second long shutdown of the CERN LHC and is designed to improve the muon trigger and tracking performance at high luminosity. The GEM detectors will add redundancy to the muon system in the 1.6 < |η| < 2.2 pseudorapidity region, where the amount of detection layers is lowest while the background rates are highest and the bending of the muon trajectories due to the CMS magnetic field is small. GEM detectors have been identified as a suitable technology to operate in the high radiation environment present in that region. The first muon endcap station will be instrumented with a double layer of triple-GEM chambers in the 1.6 < |η| < 2.2 region. The detector front-end electronics uses the custom designed VFAT3 chip to provide both fast input for the level-1 muon trigger ...

  2. Entrepreneurship in Ireland 2012: global entrepreneurship monitor (GEM)

    OpenAIRE

    Fitzsimons, Paula; O'Gorman, Colm

    2013-01-01

    Report on entrepreneurship in Ireland in the year 2012. Data used is the Global Entrepreneurship Monitor (GEM) data for Ireland and selected comparative countries. The report profiles entrepreneurs, reports on the rate of entrepreneurship in Ireland, discusses female entrepreneurship, and positions these results in the context of Irish entrepreneurship policy.

  3. gems: An R Package for Simulating from Disease Progression Models

    Directory of Open Access Journals (Sweden)

    Nello Blaser

    2015-03-01

    Full Text Available Mathematical models of disease progression predict disease outcomes and are useful epidemiological tools for planners and evaluators of health interventions. The R package gems is a tool that simulates disease progression in patients and predicts the effect of different interventions on patient outcome. Disease progression is represented by a series of events (e.g., diagnosis, treatment and death, displayed in a directed acyclic graph. The vertices correspond to disease states and the directed edges represent events. The package gems allows simulations based on a generalized multistate model that can be described by a directed acyclic graph with continuous transition-specific hazard functions. The user can specify an arbitrary hazard function and its parameters. The model includes parameter uncertainty, does not need to be a Markov model, and may take the history of previous events into account. Applications are not limited to the medical field and extend to other areas where multistate simulation is of interest. We provide a technical explanation of the multistate models used by gems, explain the functions of gems and their arguments, and show a sample application.

  4. Property of LCP-GEM in Pure Dimethyl Ether at Low Pressure

    OpenAIRE

    Takeuchi, Y; Tamagawa, T.; Kitaguchi, T; Yamada, S.; Iwakiri, W.; Asami, F.; Yoshikawa, A.; Kaneko, K.; Enoto, T.; Hayato, A.; Kohmura, T.; team, the GEMS/XACT

    2013-01-01

    We present a systematic investigation of the gain properties of a gas electron multiplier (GEM) foil in pure dimethyl ether (DME) at low pressures. The GEM is made from copper- clad liquid crystal polymer insulator (LCP-GEM) designed for space use, and is applied to a time projection chamber filled with low-pressure DME gas to observe the linear polarization of cosmic X-rays. We have measured gains of a 100 um-thick LCP-GEM as a function of the voltage between GEM electrodes at various gas pr...

  5. Continuous health monitoring of Graphite Epoxy Motorcases (GEM)

    Science.gov (United States)

    Finlayson, Richard D.; Schaafsma, David T.; Shen, H. Warren; Carlos, Mark F.; Miller, Ronnie K.; Shepherd, Brent

    2001-07-01

    Following the explosion of Delta 241 (IIR-1) on January 17th, 1997, the failure investigation board concluded that the Graphite Epoxy Motorcases (GEM's) should be inspected for damage just prior to launch. Subsequent investigations and feedback from industry led to an Aerospace Corporation proposal to instrument the entire fleet of GEM's with a continuous health monitoring system. The period of monitoring would extend from the initial acceptance testing through final erection on the launch pad. As this proposal demonstrates, (along with the increasing use of advanced composite materials in aircraft, automobiles, military hardware, and aerospace components such as rocket motorcases) a sizable need for composite health assessment measures exist. Particularly where continuous monitoring is required for the detection of damage from impacts and other sources of high mechanical and thermal stresses. Even low-momentum impacts can lead to barely visible impact damage (BVID), corresponding to a significant weakening of the composite. This damage, undetectable by visual inspection, can in turn lead to sudden and catastrophic failure when the material is subjected to a normal operating load. There is perhaps no system with as much potential for truly catastrophic failure as a rocket motor. We will present an update on our ongoing efforts with the United States Air Force Delta II Program Office, and The Aerospace Corporation. This will cover the development of a local, portable, surface-mounted, fiberoptic sensor based impact damage monitor designed to operate on a Delta II GEM during transport, storage, and handling. This system is designed to continuously monitor the GEMs, to communicate wirelessly with base stations and maintenance personnel, to operate autonomously for extended periods, and to fit unobtrusively on the GEM itself.

  6. Optimization of the gas flow in a GEM chamber and development of the GEM foil stretcher

    Directory of Open Access Journals (Sweden)

    Noto Francesco

    2014-01-01

    Full Text Available The gas electron multiplier technology has been proven to tolerate rat e larger than 50 MHz/cm2 without noticeable aging and to provide sub resolution on working chambers up to 45 cm x 45 cm. A new gas electron multiplier-based tracker is under development for the Hall A upgrade at Jefferson Lab. The chambers of the tracker have been designed in a modular way: each chamber consists of 3 adjacent gas electron multiplier modules, with an active area of 40 cm x 50 cm each. We optimized the gas flow inside the gas electron multiplier module volume, using the COMSOL physics simulator framework; the COMSOL-based analysis includes the design of the inlet and outlet pipes and the maximization of the uniformity of the gas flow. We have defined the procedures for the assembling of the gas electron multiplier modules and designed a mechanical system (TENDIGEM that will be used to stretch the GEM foils at the proper tension (few kg/cm; the TENDIGEM is based on the original design developed at LNF.

  7. Analysis of GEM properties and development of a GEM support structure for the ILD time projection chamber

    Energy Technology Data Exchange (ETDEWEB)

    Hallermann, Lea

    2010-04-15

    In the concept of the International Large Detector (ILD), developed for the International Linear Collider (ILC) a Time Projection Chamber (TPC) is envisaged as main tracking detector. Such gaseous detectors have to be equipped with amplification devices in order to enlarge the amount of charge, which is set free by ionization caused by traversing charged particles. Micro Pattern Gas Detectors (MPGDs) will be used in the ILD TPC as amplification stage. In this thesis, Gas Electron Multipliers (GEMs) - one specific MPGD species - are analyzed concerning various properties. Effective gains and energy resolutions are compared for GEM foils produced by different manufacturers. A good understanding of these observables is obtained by interpretation of the results with the help of geometrical parameters. Height profile measurements of GEM foils have been performed for the first time and the impact of non perfect flat GEMs is analyzed, especially on dE/dx determination and drift field quality. The results emphasize the need of a flat installation of GEMs in TPCs. As a consequence, a new mounting device has been developed to ensure flatness and to provide a method to cover large readout areas, as in the ILD TPC, by introducing the least possible amount of dead material into the detector. The developed structure has been tested in a TPC protoype, taking cosmic muon data. The influence of the mounting on track reconstruction, single point resolution, tracking efficiency and dE/dx measurements is quantified. The developed mounting is applicable in a large scale TPC, if some design considerations are taken into account. (orig.)

  8. Analysis of GEM properties and development of a GEM support structure for the ILD time projection chamber

    International Nuclear Information System (INIS)

    In the concept of the International Large Detector (ILD), developed for the International Linear Collider (ILC) a Time Projection Chamber (TPC) is envisaged as main tracking detector. Such gaseous detectors have to be equipped with amplification devices in order to enlarge the amount of charge, which is set free by ionization caused by traversing charged particles. Micro Pattern Gas Detectors (MPGDs) will be used in the ILD TPC as amplification stage. In this thesis, Gas Electron Multipliers (GEMs) - one specific MPGD species - are analyzed concerning various properties. Effective gains and energy resolutions are compared for GEM foils produced by different manufacturers. A good understanding of these observables is obtained by interpretation of the results with the help of geometrical parameters. Height profile measurements of GEM foils have been performed for the first time and the impact of non perfect flat GEMs is analyzed, especially on dE/dx determination and drift field quality. The results emphasize the need of a flat installation of GEMs in TPCs. As a consequence, a new mounting device has been developed to ensure flatness and to provide a method to cover large readout areas, as in the ILD TPC, by introducing the least possible amount of dead material into the detector. The developed structure has been tested in a TPC protoype, taking cosmic muon data. The influence of the mounting on track reconstruction, single point resolution, tracking efficiency and dE/dx measurements is quantified. The developed mounting is applicable in a large scale TPC, if some design considerations are taken into account. (orig.)

  9. Photovoltaik Hybrid-Solarzellen mit Nanopartikeln

    Science.gov (United States)

    Leute, Angelika

    2004-09-01

    Die organische Photovoltaik auf der Basis halbleitender Polymere bietet eine kostengünstige Alternative zu Solarzellen aus Silizium. Allerdings weisen die organischen Materialien relativ schlechte Ladungstransporteigenschaften auf. Hybrid-Solarzellen, in denen Polymere mit geeigneten anorganischen Halbleitern kombiniert sind, besitzen einerseits die praktischen Vorteile der Organik und andererseits die hohe Elektronenbeweglichkeit der anorganischen Materialien. Wissenschaftler der Technischen Universität Eindhoven haben kürzlich Hybrid-Solarzellen vorgestellt, die aus einem halbleitenden Polymer mit Zinkoxid-Nanopartikeln bestehen.

  10. Transmissionselektronenmikroskopie mit elektrostatischen Zach-Phasenplatten

    OpenAIRE

    Hettler, Simon Josef

    2015-01-01

    Elektrostatische Zach-Phasenplatten (PP) erlauben die Kontrastverstärkung von transparenten Objekten in der Transmissionselektronenmikroskopie. In der vorliegenden Arbeit wurde die Herstellung von Zach-PP optimiert und deren Auswirkung auf die Bildentstehung durch Simulationen und Experimente mit verschiedenen Proben analysiert. Die Möglichkeit der Verwendung einer Zach-PP in der Hochauflösung, der Objektwellenrekonstruktion und in Verbindung mit inelastischer Streuung wird aufgezeigt.

  11. Lernen sinojapanischer Schriftzeichen mit Bildern und Animationen

    OpenAIRE

    Soemer, Alexander

    2010-01-01

    In dieser Arbeit werden zwei visuell-mnemonische Methoden für das Paarassoziationslernen sinojapanischer Schriftzeichen (Kanji) und deren Bedeutungen vorgestellt. Die erste Methode ist das Lernen mit Bildern, welche die Bedeutung eines Schriftzeichens darstellen und dessen Elemente den Strichen des Schriftzeichens ähneln. Die zweite Methode ist das Lernen mit Animationen, welche eine Formtransformation zwischen denselben Bildern und den entsprechenden Schriftzeichen darstellen. Die beiden Met...

  12. MIT research reactor. Power uprate and utilization

    International Nuclear Information System (INIS)

    The MIT Research Reactor (MITR) is a university research reactor located on MIT campus. and has a long history in supporting research and education. Recent accomplishments include a 20% power rate to 6 MW and expanding advanced materials fuel testing program. Another important ongoing initiative is the conversion to high density low enrichment uranium (LEU) monolithic U-Mo fuel, which will consist of a new fuel element design and power increase to 7 MW. (author)

  13. Hamlet er manden i mit liv

    DEFF Research Database (Denmark)

    Rösing, Lilian Munk

    2009-01-01

    Hamlet er manden i mit liv. Min elskede. Jeg har en drøm om at frelse ham. At redde ham ud af sin mors soveværelse og ind i mit. Væk fra det ødipale Helvede han befinder sig i, fastlåst mellem et svin af en faderskikkelse (Claudius) og en alt for idealiseret far (gamle Hamlet), vågende over sin m...

  14. Regionale Dentinhaftung von Kompositrestaurationen mit unterschiedlichen Polymerisationskonzepten

    OpenAIRE

    Piltz, Carmen

    2013-01-01

    1.1.1 Hintergrund und Ziele Die Polymerisationsschrumpfung Methacrylat-basierter Komposite stellt bis zum heutigen Zeitpunkt ein bisher noch ungelöstes Problem in der modernen Zahnheilkunde dar. Insuffiziente Dentinhaftwerte mit konsekutiven postoperativen Hypersensitivitäten treiben die Dentalfirmen zur Perfektionierung dieses gefragten Füllungsmaterials an. Eine neue Kunststoffklasse (Silorane) mit der Strategie ringöffnender Monomerstrukturen während des Lichthärtens propagiert eine Min...

  15. Untersuchung der auditiven Lokalisation mit einer Lichtzeigermethode

    OpenAIRE

    Seeber, Bernhard

    2007-01-01

    Die Dissertation stellt eine neue Methode zur Untersuchung der auditiven Lokalisation vor, die sich durch eine hohe Genauigkeit und geringe methodische Einflüsse auszeichnet. Dabei wird ein Lichtzeiger rechnergesteuert mit Hilfe eines Trackballs auf die wahrgenommene Schallrichtung eingestellt. Mit Hilfe dieser Methode wird ein Verfahren zur individuell-optimalen Auswahl einer Außenohrübertragungsfunktion (AOÜF) aus mehreren fremden für Anwendungen der virtuellen Akustik entwickelt. Für die H...

  16. Ätzen von Titannitrid mit Halogenverbindungen

    OpenAIRE

    Hellriegel, Ronald

    2009-01-01

    Mit zunehmender Miniaturisierung mikroelektronischer Bauelemente steigen die Anforderungen an reproduzierbare qualitätskonforme Schichten. Um die zur Herstellung notwendigen ALD/PVD/CVD-Schichtabscheideanlagen in einen zuverlässigen Zustand zu versetzen, ist eine regelmäßige Kammerreinigung notwendig. Während des Abscheideprozesses werden nicht nur das Substrat, sondern auch die umliegenden Kammerteile beschichtet. Diese Schichten wachsen mit jedem Beschichtungszyklus weiter an. Der Stres...

  17. Effects of High Charge Densities in Multi-GEM Detectors

    CERN Document Server

    Franchino, S; Hall-Wilton, R.; Muller, H.; Oliveri, E.; Pfeiffer, D.; Resnati, F.; Ropelewski, L.; Van Stenis, M.; Streli, C.; Thuiner, P.; Veenhof, R.

    2015-01-01

    A comprehensive study, supported by systematic measurements and numerical computations, of the intrinsic limits of multi-GEM detectors when exposed to very high particle fluxes or operated at very large gains is presented. The observed variations of the gain, of the ion back-flow, and of the pulse height spectra are explained in terms of the effects of the spatial distribution of positive ions and their movement throughout the amplification structure. The intrinsic dynamic character of the processes involved imposes the use of a non-standard simulation tool for the interpretation of the measurements. Computations done with a Finite Element Analysis software reproduce the observed behaviour of the detector. The impact of this detailed description of the detector in extreme conditions is multiple: it clarifies some detector behaviours already observed, it helps in defining intrinsic limits of the GEM technology, and it suggests ways to extend them.

  18. GEMS: Underwater spectrometer for long-term radioactivity measurements

    Energy Technology Data Exchange (ETDEWEB)

    Sartini, Ludovica, E-mail: ludovica.sartini@ingv.i [Istituto Nazionale di Geofisica e Vulcanologia (INGV), Sect.Roma 2, Roma (Italy); Genoa University, Genoa (Italy); Simeone, Francesco; Pani, Priscilla [' Sapienza' University and Istituto Nazionale di Fisica Nucleare (INFN), Sect.Roma, Roma (Italy); Lo Bue, Nadia; Marinaro, Giuditta [Istituto Nazionale di Geofisica e Vulcanologia (INGV), Sect.Roma 2, Roma (Italy); Grubich, Andry; Lobko, Alexander [Institute for Nuclear Problems (INP), Belarus State University, Minsk (Belarus); Etiope, Giuseppe [Istituto Nazionale di Geofisica e Vulcanologia (INGV), Sect.Roma 2, Roma (Italy); Capone, Antonio [' Sapienza' University and Istituto Nazionale di Fisica Nucleare (INFN), Sect.Roma, Roma (Italy); Favali, Paolo [Istituto Nazionale di Geofisica e Vulcanologia (INGV), Sect.Roma 2, Roma (Italy); Gasparoni, Francesco; Bruni, Federico [Tecnomare S.p.A., Venice (Italy)

    2011-01-21

    GEMS (Gamma Energy Marine Spectrometer) is a prototype of an autonomous radioactivity sensor for underwater measurements, developed in the framework for a development of a submarine telescope for neutrino detection (KM3NeT Design Study Project). The spectrometer is highly sensitive to gamma rays produced by {sup 40}K decays but it can detect other natural (e.g., {sup 238}U,{sup 232}Th) and anthropogenic radio-nuclides (e.g., {sup 137}Cs). GEMS was firstly tested and calibrated in the laboratory using known sources and it was successfully deployed for a long-term (6 months) monitoring at a depth of 3200 m in the Ionian Sea (Capo Passero, offshore Eastern Sicily). The instrument recorded data for the whole deployment period within the expected specifications. This monitoring provided, for the first time, a continuous time-series of radioactivity in deep-sea.

  19. GEM1: First-year modeling and IT activities for the Global Earthquake Model

    Science.gov (United States)

    Anderson, G.; Giardini, D.; Wiemer, S.

    2009-04-01

    GEM is a public-private partnership initiated by the Organisation for Economic Cooperation and Development (OECD) to build an independent standard for modeling and communicating earthquake risk worldwide. GEM is aimed at providing authoritative, open information about seismic risk and decision tools to support mitigation. GEM will also raise risk awareness and help post-disaster economic development, with the ultimate goal of reducing the toll of future earthquakes. GEM will provide a unified set of seismic hazard, risk, and loss modeling tools based on a common global IT infrastructure and consensus standards. These tools, systems, and standards will be developed in partnership with organizations around the world, with coordination by the GEM Secretariat and its Secretary General. GEM partners will develop a variety of global components, including a unified earthquake catalog, fault database, and ground motion prediction equations. To ensure broad representation and community acceptance, GEM will include local knowledge in all modeling activities, incorporate existing detailed models where possible, and independently test all resulting tools and models. When completed in five years, GEM will have a versatile, penly accessible modeling environment that can be updated as necessary, and will provide the global standard for seismic hazard, risk, and loss models to government ministers, scientists and engineers, financial institutions, and the public worldwide. GEM is now underway with key support provided by private sponsors (Munich Reinsurance Company, Zurich Financial Services, AIR Worldwide Corporation, and Willis Group Holdings); countries including Belgium, Germany, Italy, Singapore, Switzerland, and Turkey; and groups such as the European Commission. The GEM Secretariat has been selected by the OECD and will be hosted at the Eucentre at the University of Pavia in Italy; the Secretariat is now formalizing the creation of the GEM Foundation. Some of GEM's global

  20. The Forward GEM Tracker of STAR at RHIC

    OpenAIRE

    Simon, F.; Balewski, J.; Fatemi, R.; Hasell, D.; Kelsey, J.; Majka, R.; Page, B.; Plesko, M.; Underwood, D.; Smirnov, N.; Sowinski, J.; Spinka, H.; Surrow, B.(Temple University, Philadelphia, PA, 19122, USA); Visser, G.

    2008-01-01

    The STAR experiment at the Relativistic Heavy Ion Collider (RHIC) at Brookhaven National Laboratory (BNL) is in the process of designing and constructing a forward tracking system based on triple GEM technology. This upgrade is necessary to give STAR the capability to reconstruct and identify the charge sign of W bosons over an extended rapidity range through their leptonic decay mode into an electron (positron) and a neutrino. This will allow a detailed study of the flavor-separated spin str...

  1. The R + D transfer in Spain: diagnostic based 2006 GEM

    International Nuclear Information System (INIS)

    The main purpose of this research is to analyse in the international context the situation today of the Spanish R and D transference from the scientific field to the firms, using 2006 GEM data as well as complementary data sources. The main findings of the study emphasize a difficult scenario concerning the R and D transference to the Spanish enterprises. Although these negative results, some data suggest a significant improvement in this area in the near future. (Author) 9 refs

  2. The gas electron multiplier (GEM): Operating principles and applications

    Science.gov (United States)

    Sauli, Fabio

    2016-01-01

    Introduced by the author in 1997, The Gas Electron Multiplier (GEM) constitutes a powerful addition to the family of fast radiation detectors; originally developed for particle physics experiments, the device and has spawned a large number of developments and applications; a web search yields more than 400 articles on the subject. This note is an attempt to summarize the status of the design, developments and applications of the new detector.

  3. Reactions of gem-Difluorinated Phosphonium Salts Induced by Light.

    Science.gov (United States)

    Panferova, Liubov I; Tsymbal, Artem V; Levin, Vitalij V; Struchkova, Marina I; Dilman, Alexander D

    2016-03-01

    gem-Difluorinated phosphonium salts, which are readily obtained from aldehydes and difluoromethylene phosphobetaine, can serve as a source of radicals under reductive conditions. An iridium complex or Hantzsch ester was used as a one-electron reducing agent when irradiated with visible light. The fluorinated radicals were trapped with various alkenes, leading to products either via a photoredox cycle (for the iridium catalyst) or via a hydrogen atom transfer (for the Hantzsch ester). PMID:26862998

  4. A Study of a Mini-drift GEM Tracking Detector

    CERN Document Server

    Azmoun, B; Franz, A; Kiselev, A; Pak, R; Phipps, M; Purschke, M L; Woody, C

    2015-01-01

    A GEM tracking detector with an extended drift region has been studied as part of an effort to develop new tracking detectors for future experiments at RHIC and for the Electron Ion Collider that is being planned for BNL or JLAB. The detector consists of a triple GEM stack with a small drift region that was operated in a mini TPC type configuration. Both the position and arrival time of the charge deposited in the drift region were measured on the readout plane which allowed the reconstruction of a short vector for the track traversing the chamber. The resulting position and angle information from the vector could then be used to improve the position resolution of the detector for larger angle tracks, which deteriorates rapidly with increasing angle for conventional GEM tracking detectors using only charge centroid information. Two types of readout planes were studied. One was a COMPASS style readout plane with 400 micron pitch XY strips and the other consisted of 2x10mm2 chevron pads. The detector was studie...

  5. Radiation monitoring of the GEM muon detectors at CMS

    Science.gov (United States)

    Dimitrov, L.; Iaydjiev, P.; Mitev, G.; Vankov, I.

    2016-09-01

    The higher energy and luminosity of future High Luminosity (HL) LHC, determines a significant increasing of the radiation background around the CMS subdetectors, and especially in the higher pseudorapidity region. Under such heavy conditions, the RPC (used in muon trigger) most probably could not operate effectively. GEM (Gas Electron Multiplier) detectors have been identified as a suitable technology to operate in the high radiation environment in that region and test at CMS will start in 2016. A monitoring system to control the absorbed radiation dose by the GEM under test is developed. Two types of sensors are used in it: RadFETs for total absorbed dose and p-i-n diodes for particle (proton and neutron) detection. The basic detector unit, called RADMON, contains two sensors of each type and can be installed at each GEM detector. The system has a modular structure, permitting to increase easily the number of controlled RADMONs: one module controls up to 12 RADMONs, organized in three group of four and communicates outside by RS 485 and CANBUS interfaces.

  6. Study of the GEM detector for the LHCb experiment upgrade

    CERN Document Server

    Santimaria, Marco

    Triple-GEM chambers, so far used in the inner region of the M1 muon station, are the ideal candidates to replace the MWPCs in the regions where, after the upgrade, the particle rate will be as high as 2 MHz/cm$^2$. Testing the triple-GEM efficiency and time resolution with different gaseous mixtures is therefore a significant step in evaluating the expected performance of the muon system after the upgrade scheduled in 2018, when the luminosity in LHCb will reach $2\\times10^{33} cm^{-2}s^{-1}$. In this thesis, a study of the GEM efficiency and time performance is conducted using a cosmic rays station at the Emilio Segrè laboratory, in the Sapienza university of Rome. Two gas mixtures are used for the measurements: Ar/CO$_2$/CF$_4$ 40:55:5 and 45:15:40. A preliminar simulation of the gas mixtures properties is performed using the software GARFIELD, focusing on electron drift velocity and specific ionization. Using 2 plastic scintillator as a muon trigger system, several measurements of efficiency and time perf...

  7. eGEMs: Pragmatic Publishing to Build a Learning Health System

    OpenAIRE

    Holve, Erin

    2012-01-01

    The Electronic Data Methods (EDM) Forum announces the launch of eGEMs (Generating Evidence and Methods to improve patient outcomes), a new, free, open access, peer-reviewed e-publication. eGEMs aims to disseminate innovative ideas about how electronic clinical data (ECD) can be leveraged in comparative effectiveness research (CER), patient-centered outcomes research (PCOR) and quality improvement (QI). eGEMs seeks submissions in four main topic areas: analytic methods, clinical informatics, g...

  8. ANTITUMOR MECHANISM OF GEM10 BY THE NATURAL KILLER ACTIVITY AND INTERLEUKIN-2 PRODUCTION

    Institute of Scientific and Technical Information of China (English)

    陈静宏; 张健; 杨占田; 陈高平; 苏敏

    2004-01-01

    Objective To investigate the anti-tumor effects of GeM10 by the natural killer(NK) cells activities and the production of Interleukin-2 (IL-2) in peripheral blood mononuclear cells (PBMNCs). Methods Assay of human NK cells activities by dye rejection assay in vitro and production of IL-2 in PBMNC by IL-2 bioassay with IL-2 dependent cell line CTLL2 and MTT colorometric method. Results GeM10 could significantly stimulate NK activities (60μg*mL -1 GeM10: 17.077±7.665, 120μg*mL-1 GeM10: 24.9±13.04; control: 7.72±4.64, P<0.05). GeM10 could up-regulate the production of IL-2 of PBMNCs in tumor patients(60μg*mL-1 GeM10: 2.965±1.183; 120μg*mL-1 GeM10: 2.28±0.847; control: 1.792±0.823, P<0.05).Conclusion The GeM10 not only can stimulate the NK activities but also increase the IL-2 production by PBMNCs in tumor patients. These findings indicate that the GeM10 may have promise as an anti-tumor drug and a biological response modifier in clinic.

  9. Discriminating cosmic muon and x-ray based on rising time using GEM detector

    OpenAIRE

    Hui-Yin, Wu; Sheng-Ying, Zhao; Xiao-Dong, Wang; Xian-Ming, Zhang; Hui-Rong, Qi; Wei, Zhang; Ke-Yan, Wu; Bi-Tao, Hu; Yi, Zhang

    2015-01-01

    Gas electron multiplier(GEM) detector is used in Cosmic Muon Scattering Tomography and neutron imaging in the last decade. In this work, a triple GEM device with an effective readout area of 10 cm X 10 cm is developed, and an experiment of discriminating between cosmic muon and x-ray based on rising time is tested. The energy resolution of GEM detector is tested by 55Fe ray source to prove the GEM detector has a good performance. The analysis of the complete signal-cycles allows to get the ri...

  10. Statistical exploration of gaseous elemental mercury (GEM measured at Cape Point from 2007 to 2011

    Directory of Open Access Journals (Sweden)

    A. D. Venter

    2015-02-01

    Full Text Available The authors evaluated continuous high resolution gaseous elemental mercury (GEM data from the Cape Point Global Atmosphere Watch (CPT GAW station with different statistical analysis techniques. GEM data was evaluated by cluster analysis and the results indicated that two clusters, separated at 0.904 ng m−3, existed. The air mass history for the two-cluster solution was investigated by means of back-trajectory analysis. The air mass back-trajectory net result showed lower GEM concentrations originating from the sparsely populated semi-arid interior of SA and the marine environment, whereas higher GEM concentrations originated predominately along the coast of SA that most likely coincide with trade routes and industrial activities in urban areas along the coast. Considering the net result from the air mass back-trajectories, it is evident that not all low GEM concentrations are from marine origin, and similarly, not all high GEM concentrations have a terrestrial origin. Equations were developed by means of multi-linear regression (MLR analysis that allowed for the estimation/prediction of atmospheric GEM concentrations from other atmospheric parameters measured at the CPT GAW station. These equations also provided some insight into the relation and interaction of GEM with other atmospheric parameters. Both measured and MLR calculated data confirm a decline in GEM concentrations at CPT GAW over the period evaluated.

  11. MIT 12 Tesla Coil test results

    International Nuclear Information System (INIS)

    Test results from the MIT 12 Tesla Coil experiment are presented. The coil was tested in the High Field Test Facility (HFTF) of the Lawrence Livermore National Laboratory in October 1984 and January 1985. The experiment measured the performance of an Internally Cooled, Cabled Superconductor (ICCS) of practical size, intended for use in magnetic fusion experiments. The MIT coil carried 15 kA at 11 T for 5 min with no sign of instability. A half turn length in a 10 T field was able to absorb a heat load in 4 msec of more than 200 mJ/cm3 of cable volume while carrying a current of 12 kA. The MIT coil successfully met the performance requirements of the Department of Energy's 12 Tesla Coil Program

  12. Enantioselektive Transferhydrierung mit Ruthenium(II)-Komplexen

    OpenAIRE

    Henning, Frauke

    2003-01-01

    Eine Vielzahl chiraler Liganden und Komplexe wurden als Katalysatoren in der enantioselektiven Transferhydrierung von Acetophenon mit den Wasserstoffdonoren 2-Propanol und Ameisensäure getestet. Vier dreizähnige axial chirale Binaphthyle erzielen in situ mit Tris-(triphenylphosphanyl)ruthenium(II)-chlorid hohe Enantiomerenüberschüsse von bis zu 98% und Ausbeuten über 90% unter optimierten Reaktionsbedingungen. Es wird ein deutlicher OH-Effekt beobachtet, während ein NH-Effekt nicht bestätigt ...

  13. Entwicklung eines Ultraschallkatheters mit integriertem Mikroantrieb

    OpenAIRE

    Ledworuski, Ralf

    2006-01-01

    In der medizinischen Diagnostik werden Ultraschallkatheter häufig eingesetzt, um Gefäße wie z. B. Arterien oder den Gallengang auf Ablagerungen und krankhafte Veränderungen zu untersuchen und diese in einem sehr frühen Stadium zu erkennen. Voraussetzung dafür ist eine kontrastreiche Gefäßdarstellung mit guter Auflösung. Kathetersysteme aus dem Bereich des intravaskulären Ultraschalls (IVUS) und Minisonden des endoskopischen Ultraschalls (EUS) erzeugen zirkuläre Ultraschallbilder mit dem Ultra...

  14. Herstellung von Metallkomplexen mit schwefelreichen Liganden

    OpenAIRE

    Chrzanowski, Lars Stefan von

    2005-01-01

    Die vorliegende Arbeit beschäftigt sich mit der Synthese und Charakterisierung von neuen Übergangsmetallkomplexen der ersten und zweiten Nebengruppe mit schwefelreichen Liganden. Die neuen Thiokronenetherkomplexe (1,4,7,10-Tetrathiacyclododecan)silber(I)trifluoromethansulfonat 5, Di(3,6,9,14-Tetrathiabicyclo-[9.2.1]tetradeca-11,13-dien)silber(I)trifluoromethansulfonat 6, (1,4,7,10,13,16-Hexathiacyclooctadecan)silber(I)trifluoromethansulfonat 7 und Diiodo(1,4,7,10,13,16-Hexathiacyclooctadecan)...

  15. 3. Zusammenarbeit mit Osteuropa und der GUS

    OpenAIRE

    Guggenbühl, Tanja; Tschumi Canosa, Xavier

    2009-01-01

    Die neue Rechtsgrundlage für die Zusammenarbeit mit den Staaten Osteuropas und der Gemeinschaft Unabhängiger Staaten (GUS) trat am 1. Juni 2007 in Kraft. Sie ist sowohl für den Beitrag der Schweiz zur Erweiterung der Europäischen Union (EU) als auch für die Zusammenarbeit mit den Oststaaten massgebend. Während der Bundesrat eine Kürzung der Mittel für die Ostzusammenarbeit vorgesehen hatte, um dadurch einen Teil der Finanzierung der Kohäsionsmilliarde zu kompensieren, konnte der Rahmenkredit ...

  16. Evaluation of ozone profile and tropospheric ozone retrievals from GEMS and OMI spectra

    Directory of Open Access Journals (Sweden)

    J. Bak

    2012-09-01

    Full Text Available Korea is planning to launch the GEMS (Geostationary Environment Monitoring Spectrometer instrument into a Geostationary (GEO platform in 2018 to monitor tropospheric air pollutants on an hourly basis over East Asia. GEMS will measure backscattered UV radiances covering the 300–500 nm wavelength range with a spectral resolution of 0.6 nm. The main objective of this study is to evaluate ozone profiles and stratospheric column ozone amounts retrieved from simulated GEMS measurements. Ozone Monitoring Instrument (OMI Level 1B radiances, which have the spectral range 270–500 nm at spectral resolution of 0.42–0.63 nm, are used to simulate the GEMS radiances. An optimal estimation-based ozone profile algorithm is used to retrieve ozone profiles from simulated GEMS radiances. Firstly, we compare the retrieval characteristics (including averaging kernels, degrees of freedom for signal, and retrieval error derived from the 270–330 nm (OMI and 300–330 nm (GEMS wavelength ranges. This comparison shows that the effect of not using measurements below 300 nm on tropospheric ozone retrievals is insignificant. However, the stratospheric ozone information decreases greatly from OMI to GEMS, by a factor of ∼2. The number of the independent pieces of information available from GEMS measurements is estimated to 3 on average in the stratosphere, with associated retrieval errors of ∼1% in stratospheric column ozone. The difference between OMI and GEMS retrieval characteristics is apparent for retrieving ozone layers above ∼20 km, with a reduction in the sensitivity and an increase in the retrieval errors for GEMS. We further investigate whether GEMS can resolve the stratospheric ozone variation observed from high vertical resolution EOS Microwave Limb Sounder (MLS. The differences in stratospheric ozone profiles between GEMS and MLS are comparable to those between OMI and MLS above ∼3 hPa (∼40 km except with slightly larger biases and larger

  17. Resolution studies of a GEM-based TPC

    Energy Technology Data Exchange (ETDEWEB)

    Killenberg, M.

    2006-12-15

    Currently there are four different concept studies trying to optimise the detector for the requirements at the ILC. In three of these detector concepts a time projection chamber (TPC) is foreseen as the main tracking device. To achieve the intended spatial resolution of 100 {mu}m, micro pattern gas detectors (MPGD) are considered for gas amplification. The two different MPGDs discussed for the ILC TPC are Micro-Mesh Gaseous Detectors (Micromegas) and Gas Electron Multiplier foils (GEMs). The current thesis shows resolution studies with a TPC prototype equipped with a triple GEM readout structure. A hodoscope made up of silicon strip sensors gives a precision reference track, allowing an unbiased measurement of the spatial resolution. High statistics measurements have been conducted at the DESY test beam facility, which provides positrons with a tunable energy between 1 GeV and 6 GeV. Using the independent measurement of the hodoscope allows systematic studies of the homogeneity of the TPC's electric field. The fluctuations of the field in the chamber's central region were found to be {delta}E/E=8.10{sup -3}. Field distortions have been determined and corrected, reducing the remaining deviations to a level well below the spatial resolution of the TPC. One important task is to reduce the number of ions drifting back into the sensitive volume. Special GEM settings with minimised ion backdrift have been examined with respect to their influence on the spatial resolution and it was found that the spatial resolution is not degraded using these special settings. The TPC prototype has been operated in a 4 T magnetic field, provided by a superconducting solenoid located at DESY Hamburg. Again the spatial resolution measured with the ion backdrift optimised settings is compared to that achieved with nonoptimised settings. In both cases the measured resolution is approximately 130 {mu}m. (orig.)

  18. Grosse Axiallager mit Hybridschmierung - Theoretische und experimentelle Betrachtungen

    DEFF Research Database (Denmark)

    Santos, Ilmar; Fuerst, Axel

    2003-01-01

    Der vorliegende Artikel praesentiert die Simulation eines grossen axialen Kippsegmentlagers unter Beruecksichtigung der hybriden Schmierung, d.h. gleichzeitige hydrodynamische und hydrostatische Schmierung. Ein Vergleich mit Messungen zeigt, dass fuer das betrachtete Lager mit 2,2 m Durchmesser d...

  19. A Time Projection Chamber with GEM-Based Readout

    CERN Document Server

    Attié, David; Bellerive, Alain; Bezshyyko, Oleg; Bhattacharya, Deb Sankar; Bhattacharya, Purba; Bhattacharya, Sudeb; Caiazza, Stefano; Colas, Paul; De Lentdecker, Gilles; Dehmelt, Klaus; Desch, Klaus; Diener, Ralf; Dixit, Madhu; Fleck, Ivor; Fujii, Keisuke; Fusayasu, Takahiro; Ganjour, Serguei; Gao, Yuanning; Gros, Philippe; Hayman, Peter; Hedberg, Vincent; Ikematsu, Katsumasa; Jönsson, Leif; Kaminski, Jochen; Kato, Yukihiro; Kawada, Shin-ichi; Killenberg, Martin; Kleinwort, Claus; Kobayashi, Makoto; Krylov, Vladyslav; Li, Bo; Li, Yulan; Lundberg, Björn; Lupberger, Michael; Majumdar, Nayana; Matsuda, Takeshi; Mehdiyev, Rashid; Mjörnmark, Ulf; Müller, Felix; Münnich, Astrid; Mukhopadhyay, Supratik; Ogawa, Tomohisa; Oskarsson, Anders; Österman, Lennart; Peterson, Daniel; Riallot, Marc; Rosemann, Christoph; Roth, Stefan; Schade, Peter; Schäfer, Oliver; Settles, Ronald Dean; Shirazi, Amir Noori; Smirnova, Oxana; Sugiyama, Akira; Takahashi, Tohru; Tian, Junping; Timmermans, Jan; Titov, Maksym; Tsionou, Dimitra; Vauth, Annika; Wang, Wenxin; Watanabe, Takashi; Werthenbach, Ulrich; Yang, Yifan; Yang, Zhenwei; Yonamine, Ryo; Zenker, Klaus; Zhang, Fan

    2016-01-01

    For the International Large Detector concept at the planned International Linear Collider, the use of time projection chambers (TPC) with micro-pattern gas detector readout as the main tracking detector is investigated. In this paper, results from a prototype TPC, placed in a 1 T solenoidal field and read out with three independent GEM-based readout modules, are reported. The TPC was exposed to a 6 GeV electron beam at the DESY II synchrotron. The efficiency for reconstructing hits, the measurement of the drift velocity, the space point resolution and the control of field inhomogeneities are presented.

  20. Life with quintuplets: transitioning GeMS into regular operations

    Science.gov (United States)

    Garrel, Vincent; Van Dam, Marcos A.; Neichel, Benoît; Vidal, Fabrice; Sivo, Gaetano; Marin, Eduardo; Montes, Vanessa; Serio, Andrew; Arriagada, Gustavo; Trujillo, Chadwick; Rambold, William N.; Gigoux, Pedro; Galvez, Ramon; Moreno, Cristian; Araujo Hauck, Constanza; Vucina Parga, Tomislav; Donahue, Jeff; Marchant, Claudio; Gausachs, Gaston; Collao, Fabian; Carrasco Damele, Eleazar R.; Pessev, Peter; Lopez, Ariel

    2014-08-01

    The Gemini Multi-conjugate adaptive optics System (GeMS) at the Gemini South telescope in Cerro Pachon is the first sodium Laser Guide Star (LGS) adaptive optics (AO) system with multiple guide stars. It uses five LGSs and two deformable mirrors (DMs) to measure and compensate for distortions induced by atmospheric turbulence. After its 2012 commissioning phase, it is now transitioning into regular operations. Although GeMS has unique scientific capabilities, it remains a challenging instrument to maintain, operate and upgrade. In this paper, we summarize the latest news and results. First, we describe the engineering work done this past year, mostly during our last instrument shutdown in 2013 austral winter, covering many subsystems: an erroneous reconjugation of the Laser guide star wavefront sensor, the correction of focus field distortion for the natural guide star wavefront sensor and engineering changes dealing with our laser and its beam transfer optics. We also describe our revamped software, developed to integrate the instrument into the Gemini operational model, and the new optimization procedures aiming to reduce GeMS time overheads. Significant software improvements were achieved on the acquisition of natural guide stars by our natural guide star wavefront sensor, on the automation of tip-tilt and higher-order loop optimization, and on the tomographic non-common path aberration compensation. We then go through the current operational scheme and present the plan for the next years. We offered 38 nights in our last semester. We review the current system efficiency in term of raw performance, completed programs and time overheads. We also present our current efforts to merge GeMS into the Gemini base facility project, where night operations are all reliably driven from our La Serena headquarter, without the need for any spotter. Finally we present the plan for the future upgrades, mostly dedicated toward improving the performance and reliability of the

  1. GEMS/WATER—全球水质监测

    Institute of Scientific and Technical Information of China (English)

    Silvio; Barabas; 张绍宗

    1983-01-01

    GEMS/WATER是联合国组织实施的一项监测世界范围河流、湖泊和含水层中水质的国际合作研究计划。目前,在50个国家中有300个以上的监测站向设在加拿大的全球中心提供水质报告。数据包括水质的13个基本参数。

  2. Long-term stability test of a triple GEM detector

    CERN Document Server

    Adak, R P; Das, S; Ghosal, D; Ghosh, S K; Mondal, A; Nag, D; Nayak, T K; Patra, R N; Prasad, S K; Raha, S; Sahu, P K; Sahu, S; Swain, S

    2016-01-01

    The main aim of the study is to perform the long-term stability test of gain of the single mask triple GEM detector. A simple method is used for this long- term stability test using a radioactive X-ray source with high activity. The test is continued till accumulation of charge per unit area > 12.0 mC/mm2. The details of the chamber fabrication, the test set-up, the method of measurement and the test results are presented in this paper.

  3. Sexualisierte Gewalt gegen Menschen mit Behinderung in Institutionen

    OpenAIRE

    Zemp, Aiha

    2002-01-01

    Es werden zwei Studien vorgestellt: "'Weil das alles weh tut mit Gewalt' - Sexuelle Ausbeutung von Mädchen und Frauen mit Behinderung" (Zemp u. Pircher 1996) und "Sexualisierte Gewalt im behinderten Alltag - Jungen und Männer mit Behinderung als Opfer und Täter" (Zemp et al. 1997). In den vorliegenden Untersuchungen haben wir uns auf Frauen und Männer mit Behinderung konzentriert, die aufgrund ihrer körperlichen, geistigen und/oder psychischen Behinderung in einer Institution leben. S...

  4. Abbildendes Mikrowellen-Spektrometer mit Apertursynthese

    OpenAIRE

    Jirousek, Matthias

    2011-01-01

    In dieser Arbeit wird die neuartige Kombination des hochauflösenden radiometrischen Abbildungsverfahrens Apertursynthese mit einer spektralen Messung untersucht und im System ANSAS umgesetzt. Diese Verknüpfung ermöglicht z.B. in der Fernerkundung eine umfangreichere Erdbeobachtung zur genaueren Erfassung geophysikalischer Parameter. Die messtechnische Verifikation wurde anhand verschiedener Abbildungsszenarien untersucht und damit die Machbarkeit eines solchen Systemkonzepts demonstriert.

  5. MIT professor wins major international math prize

    CERN Multimedia

    Allen, S

    2004-01-01

    Mathematicians Isadore Singer of MIT and Sir Michael Francis Atiyah of the University of Edinburgh will share an $875,000 award as winners of the second Abel Prize, which some hope will come to be seen as a Nobel Prize for math.

  6. Use of aluminium plates to simulate the dosimetry of gems during e-beam irradiation

    International Nuclear Information System (INIS)

    The e-beam technology is used in the industrial irradiation of several products like turf, sterilization of medical products, cosmetics, polymers, food, and gems. More than 70% of the gems commercialized in the world receive treatments similar to those present in nature, including heat, and irradiation, in order to improve their value. Since aluminum has a density similar to that of several commercial gems, this paper presents a study of the penetration of electrons in calibrated aluminum plates simulating several different thicknesses ranging from 5 to 30 mm, and comparing with the one obtained in gems. This allows the monitoring of the dose received by gems during irradiation with e-beam systems measuring the delivered surface dose. This procedure is very important for industrial processing of stones due to the irregularities present on most gems, what makes dosimetry a very complex task. The determination of the thicknesses of the gems for which the surface dose is the lowest dose on the whole product assures the precise determination of the minimum dose received by the gems during industrial processing. (author)

  7. A scintillating GEM for 2D-dosimetry in radiation therapy

    NARCIS (Netherlands)

    Timmer, JH; van Vuure, TL; Bom, [No Value; van Eijk, CW; de Haas, J; Schippers, JM

    2002-01-01

    The first results of a study on the properties of a gaseous scintillation detector based on a Gas Electron Multiplier (GEM) are reported. The detector is designed for use in position-sensitive dosimetry applications in radiation therapy. A double GEM system, operating in a 90 10% Ar-CO2 gas mixture

  8. Use of aluminium plates to simulate the dosimetry of gems during e-beam irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Fortes, Marcio Z.; Sousa, Fernando N.C. de; Boente, Otavio C., E-mail: mzamboti@aceletron.com.b, E-mail: fernando.nuno@aceletron.com.b, E-mail: otavio@aceletron.com.b [Aceletron Irradiacao Industrial, Rio de Janeiro, RJ (Brazil); Sousa, Nuno R.A., E-mail: engenheiro.nuno.sousa@gmail.co [Universidade Federal do Rio de Janeiro (UFRJ), RJ (Brazil). Dept. de Engenharia Mecanica

    2009-07-01

    The e-beam technology is used in the industrial irradiation of several products like turf, sterilization of medical products, cosmetics, polymers, food, and gems. More than 70% of the gems commercialized in the world receive treatments similar to those present in nature, including heat, and irradiation, in order to improve their value. Since aluminum has a density similar to that of several commercial gems, this paper presents a study of the penetration of electrons in calibrated aluminum plates simulating several different thicknesses ranging from 5 to 30 mm, and comparing with the one obtained in gems. This allows the monitoring of the dose received by gems during irradiation with e-beam systems measuring the delivered surface dose. This procedure is very important for industrial processing of stones due to the irregularities present on most gems, what makes dosimetry a very complex task. The determination of the thicknesses of the gems for which the surface dose is the lowest dose on the whole product assures the precise determination of the minimum dose received by the gems during industrial processing. (author)

  9. Wrestling with Pedagogical Change: The TEAL Initiative at MIT

    Science.gov (United States)

    Breslow, Lori

    2010-01-01

    In the late 1990s, the physics department at the Massachusetts Institute of Technology (MIT) had a problem. The department was responsible for teaching the two required physics courses that are part of the General Institute Requirements (GIRs), MIT's core curriculum--Physics I (mechanics, or in MIT parlance, 8.01) and Physics II (electricity and…

  10. AdMit: adaptive mixtures of student-t distributions

    NARCIS (Netherlands)

    D. David (David); L.F. Hoogerheide (Lennart); H.K. van Dijk (Herman)

    2009-01-01

    textabstractThis note presents the package AdMit (Ardia et al., 2008, 2009), an R implementation of the adaptive mixture of Student-t distributions (AdMit) procedure developed by Hoogerheide (2006); see also Hoogerheide et al. (2007); Hoogerheide and van Dijk (2008). The AdMit strategy consists of t

  11. PREFACE: Science's gem: diamond science 2009 Science's gem: diamond science 2009

    Science.gov (United States)

    Mainwood, Alison; Newton, Mark E.; Stoneham, Marshall

    2009-09-01

    Natural diamond has been valued for its appearance and mechanical properties for at least two thousand years. As a gem stone diamond is unsurpassed. However, scientific work, especially in the last 20 years, has demonstrated that diamond has numerous surprising properties and many unique ones. Some of the extreme properties have been known for many years, but the true scale of diamond's other highly desirable features is still only coming to light as control in the synthesis of diamond, and hence material perfection, improves. The ultimate prize for man-made diamond is surely not in the synthesis of gem stones, but in delivering technological solutions enabled by diamond to the challenges facing our society today. If the special properties are to be exploited to their full potential, at least four crucial factors must be considered. First, there must be sufficient scientific understanding of diamond to make applications effective, efficient and economical. Secondly, the means of fabrication and control of properties have to be achieved so that diamond's role can be optimised. Thirdly, it is not enough that its properties are superior to existing materials: they must be so much better that it is worth initiating new technologies to exploit them. Finally, any substantial applications will have to address the society's major needs worldwide. The clear technology drivers for the 21st century come from the biomedical technologies, the demand for energy subject to global constraints, and the information technologies, where perhaps diamond will provide the major enabling technology [1]. The papers in this volume concern the solid state physics of diamond, and primarily concern the first two factors: understanding, and control of properties. They address many of the outstanding basic problems, such as the identification of existing defects, which affect the material's properties, both desirable and less so. Regarding future substantial applications, one paper discusses

  12. Characterization of GEM foils and materials simulation, measurements and interferometric monitoring tools

    CERN Document Server

    Benussi, Luigi

    2015-01-01

    The GE1/1 CMS project consists of 144 GEM chambers of about 0.5 qm active area each, based on the triple GEMs technology, to be installed in the very forward region of the CMS endcap during the long shutdown of LHC in 2108-2019. GE1/1 chambers will be operated for decades in harsh environment, and are expected to perform consistently providing good space and time resolution and excellent rate capabilities. An extensive material science simulation and measurement campaign is in progress to characterize GEM materials, with main focus on the GEM foils. Results are presented on full Finite Element Analysis simulations, measurement of tensile properties and humidity absorption coefficients, both for unused and irradiated samples. Preliminary results are shown on interferometric methods based on Moirè fringes for the monitoring of GEM foils mechanical properties during chamber construction.

  13. A preliminary geochemical study of sedimentary gem deposits of Sri Lanka

    International Nuclear Information System (INIS)

    The geochemical abundances of 22 elements from the < 0.63 μm fraction of gem-bearing alluvial gravel from the main gem fields of Sri Lanka have been studied. These abundances are compared with those in the probable source rocks. Be and Zr are generally enriched in the gem-bearing sediments compared with most alkali and alkaline earths, which are depleted. When compared to the metal contents of average shales, the < 0.63 μm fraction of the gem sediments of Sri Lanka is enriched in Be, Zr, Ti, V, Cr, Fe, Co, Ni, Cu and Zn. The charnockites and the gneisses of the area are rich in most of these elements and in the gem-bearing sediments, they are presumably found in diadochic substitution in minerals, or adsorbed by a variety of clay minerals, secondary Fe and Mn hydroxides and oxides and primary minerals. (author)

  14. Investigations on Important Properties of the 10 cm x 10 cm GEM Prototype

    CERN Document Server

    Saenboonruang, Kiadtisak; Kulasri, Kittipong; Ritthirong, Anawat

    2015-01-01

    The Gas Electron Multiplier (GEM) detector is one of promising particle and radiation detectors that has been improved greatly from previous gas detectors. The improvement includes better spatial resolutions, higher detection rate capabilities, and flexibilities in designs. In particular, the 10 cm x 10 cm GEM prototype is designed and provided by the Gas Detectors Development group (GDD) at CERN, Switzerland. With its simplicity in operations and designs, while still maintaining high qualities, the GEM prototype is suitable for both start-up and advanced researches. This article aims to report the investigations on some important properties of the 10 cm x 10 cm GEM detector using current measurement and signal counting. Results have shown that gains of the GEM prototype exponentially increase as voltage supplied to the detector increases, while the detector reaches full efficiency (plateau region) when the voltage is greater than 4100 V. In terms of signal sharing between X and Y strips of the readout, X str...

  15. Investigation of GEM-Micromegas Detector on X-ray Beam of Synchrotron Radiation

    CERN Document Server

    Zhang, YuLian; Hu, BiTao; Fan, ShengNan; Wang, Bo; Liu, Mei; Zhang, Jian; Liu, RongGuang; Chang, GuangCai; Liu, Peng; Ouyang, Qun; Chen, YuanBo; Yi, FuTing

    2013-01-01

    To solve the discharge of the standard Bulk Micromegas and GEM detector, the GEM-Micromegas detector was developed in Institute of High Energy Physics. Taking into account the advantages of the two detectors, one GEM foil was set as a preamplifier on the mesh of Micromegas in the structure and the GEM preamplification decreased the working voltage of Micromegas to reduce the effect of the discharge significantly. In the paper, the performance of detector in X-ray beam was studied at 1W2B laboratory of Beijing Synchrotron Radiation Facility. Finally, the result of the energy resolution under various X-ray energies was given in different working gases. It indicated that the GEM-Micromegas detector had the energy response capability in all the energy range and it could work better than the standard Bulk-Micromegas.

  16. Development of Gas Electron Multiplier(GEM) for digital radiographic system

    CERN Document Server

    Moon, B S; Lee, J W

    2000-01-01

    Two computer programs SHOWFIELD and IMAGEQUAL have been developed. SHOWFIELD is used to draw electric field lines for GEM detectors and IMAGEQUAL is used to study the spatial resolution of x-ray images. Various simulation runs have been carried out using EGS4 to study the characteristics of electrons generated by micro-channel plates and Ar, Xe gases. A prototype GEM detector was developed through this project. The GEM detector is composed of a pair of GEM plates, a micro-channel plate, readout circuit in a gas filled chamber. GEM plate were made in CERN to meet KAERI's design specification and the micro-channel plates were purchased from Proxitronic company.

  17. A new glass GEM with a single-sided guard-ring structure

    International Nuclear Information System (INIS)

    The gas electron multiplier (GEM) is a gaseous detector that is widely used in many applications. Our glass GEM (G-GEM) comprises a photo-etchable glass (PEG3, HOYA Corporation, Japan). Our research indicated that it shows superior performance compared with other gas detectors. In this article, a new type of G-GEM is introduced. It has a guard-ring structure around the holes in order to improve the spark tolerance by reducing the total capacitance of each hole structure. A measured gas gain of approximately 7500 is attained for this new G-GEM with a single-sided guard-ring structure using a gas mixture of Ar (90%) and CH4 (10%) in the gas flow mode. An energy resolution of 17.3% (FWHM) is also achieved with a collimated 6 keV X-ray beam. The results of a 10 to 12 hour gas gain stability measurements are also shown. (author)

  18. Formation of GEMS from shock-accelerated crystalline dust in superbubbles

    CERN Document Server

    Westphal, A J

    2004-01-01

    Interplanetary dust particles (IDPs) contain enigmatic sub-micron components called GEMS (Glass with Embedded Metal and Sulfides). The compositions and structures of GEMS indicate that they have been processed by exposure to ion- izing radiation but details of the actual irradiation environment(s) have remained elusive. Here we propose a mechanism and astrophysical site for GEMS formation that explains for the first time the following key properties of GEMS; they are stoichiometrically enriched in oxygen and systematically deple- ted in S, Mg, Ca and Fe (relative to solar abundances), most have normal (solar) oxygen isotopic compositions, they exhibit a strikingly narrow size distribution (0.1-0.5 $\\mu$m diameter), and some of them contain ``relict'' crystals within their glass matrices. We show that these properties are incon- sistent with amorphization by particles accelerated by diffusive shock accel- eration. Instead, we propose that GEMS are formed from crystalline grains that condense in outflows from m...

  19. Two-dimensional position sensitive ionization chamber with GEM

    Science.gov (United States)

    Kitamura, Noritaka; Noro, Tetsuo; Sakaguchi, Satoshi; Takao, Hideaki; Nishio, Yasutaka

    2014-09-01

    We have been developing a multi-anode ionization chamber for Accelerator Mass Spectrometry (AMS) at Kyushu University. Furthermore, we are planning to construct a neutron detector with high position resolution by combining the chamber with Gas Electron Multiplier (GEM) and a neutron converter. One of purposes is the measurement of p-> , pn knockout reaction from unstable nuclei. The multi-anode ionization chamber is composed of subdivided multiple anodes, a cathode to produce an uniform electric field, and a Frisch grid. The chamber must have position sensitivity because obtaining a beam profile is required for AMS measurements, where counting loss should be avoided. Also in the case of the neutron detector, it is necessary to measure the position to deduce the scattering angles. We have recently established a two-dimensional position readout system by the following methods: the measurement of horizontal position is enabled by trimming some anodes into wedge-like shape, and vertical position can be determined by the ratio of induced charge on the grid to the total charge on anodes. In addition, improvement of S/N ratio is important for isotope separation and position resolution. We installed a rectangular-shaped GEM and tried improving S/N ratio by electron amplification.

  20. The stable K0 giant star β Gem

    Energy Technology Data Exchange (ETDEWEB)

    Gray, David F., E-mail: dfgray@uwo.ca [Department of Physics and Astronomy, University of Western Ontario, 1151 Richmond Street, London, Ontario, N6A 3K7 (Canada)

    2014-12-01

    A nine-season spectroscopic study of the photosphere of β Gem (K0 III) shows this low-luminosity giant to be stable, with no effective temperature variations above ∼2 K, and no secular temperature variations over the 2002-2010 time span above 0.2 K per year. The radial-velocity variations are consistent with an orbital variation of ∼40 m s{sup –1}. The projected rotation rate is found to be 1.70 ± 0.20 km s{sup –1} with a macroturbulence dispersion of 4.53 ± 0.10 km s{sup –1}. The third-signature plot is also invariant and shows a granulation velocity gradient 20% smaller than the solar gradient. The absolute shift of the third-signature plot gives a blueshift-corrected radial velocity of 3385 ± 70 m s{sup –1}. Bisector mapping of the Fe I λ6253 line yields a flux deficit of 12% ± 1% in area, somewhat smaller than for other giants, but the shape and the position of the peak at 4.8 km s{sup –1} is consistent with other giants. All of the investigated photospheric parameters are consistent with β Gem being a low-luminosity giant in agreement with its absolute magnitude.

  1. Decadal predictions with the HiGEM high resolution global coupled climate model: description and basic evaluation

    OpenAIRE

    Shaffrey, LC; Stevens, David; Hodson, D.; Robson, J.; Hawkins, E.; Polo, I; Stevens, Ian; Sutton, RT; Lister, G.; Iwi, AM; Smith, D.

    2016-01-01

    This paper describes the development and basic evaluation of decadal predictions produced using the HiGEM coupled climate model. HiGEM is a higher resolution version of the HadGEM1 Met Office Unified Model. The horizontal resolution in HiGEM has been increased to 1.25◦ × 0.83◦ in longitude and latitude for the atmosphere, and 1/3◦ × 1/3◦ globally for the ocean. The HiGEM decadal predictions are initialised using an anomaly assimilation scheme that relaxes anomalies of ocean temperature and sa...

  2. Flight research with the MIT Daedalus prototype

    Science.gov (United States)

    Bussolari, Steven R.; Youngren, Harold H.; Langford, John S.

    1987-01-01

    The MIT Light Eagle human-powered aircraft underwent long-duration testing over Rogers Dry Lake in California during January, 1987. Designed as a prototype for the MIT Daedalus Project, the Light Eagle's forty-eight flights provided pilot training, established new distance records for human-powered flight, and provided quantitative data through a series of instrumented flight experiments. The experiments focused on: (1) evaluating physiological loads on the pilot, (2) determining airframe power requirements, and (3) developing an electronic flight control system. This paper discusses the flight test program, its results and their implications for the follow-on Daedalus aircraft, and the potential uses of the Light Eagle as a low Reynolds number testbed.

  3. Aufgabenorientierte Kopplung von Sensoren mit unterschiedlichen Abtasteigenschaften

    OpenAIRE

    Robl, Christian

    2007-01-01

    Die Sensorkopplung auf Signal-Level für Regelungszwecke wird in drei funktionelle Blöcke - Synchronisation, Sensordatenvorverarbeitung und Sensordatenfusion - unterteilt. Es werden dafür Methoden erarbeitet und mit klassischen Verfahren verglichen. Die Sensoren werden anhand ihres Abtastverhaltens in vier Klassen unterteilt. Es werden dafür geeignete Simulationsmodelle abgeleitet. Die Erweiterung von MatLab/SimuLink ermöglicht die Verwendung des gleichen Blockschaltbilds für Software- und Har...

  4. Kurz zum Klima: Solarstromboom mit Nebenwirkungen

    OpenAIRE

    Johann Wackerbauer; Jana Lippelt

    2012-01-01

    Die deutsche Solarstrombranche befindet sich in einer Phase der Marktbereinigung. Der Sonnenstromboom geht mit Überkapazitäten bei den Herstellern von Solarzellen und Modulen und fallenden Preisen einher. Trotz einer großzügigen Förderung gerät die als Zukunftsindustrie bezeichnete deutsche Photovoltaikindustrie in eine Absatzkrise und die Förderung der Photovoltaik in Deutschland erweist sich als industriepolitisches Debakel: Während die asiatischen Produzenten gezielt ihre Marktanteile ausb...

  5. MIT App Inventor: Enabling Personal Mobile Computing

    OpenAIRE

    Pokress, Shaileen Crawford; Veiga, José Juan Dominguez

    2013-01-01

    MIT App Inventor is a drag-and-drop visual programming tool for designing and building fully functional mobile apps for Android. App Inventor promotes a new era of personal mobile computing in which people are empowered to design, create, and use personally meaningful mobile technology solutions for their daily lives, in endlessly unique situations. App Inventor's intuitive programming metaphor and incremental development capabilities allow the developer to focus on the logic for programming ...

  6. Textualizing cultures: thinking beyond the MIT controversy

    OpenAIRE

    Callahan, William A.

    2015-01-01

    This essay examines how the MIT Controversy hardened identities in terms of the timeworn template of geopolitical conflict of national stereotypes. It critically analyzes the Chinese students’ response to the “Visualizing Cultures” project by putting it in the context of the PRC’s patriotic education policy that securitizes culture by focusing on identity as difference in a zero-sum game that distinguishes civilization from barbarism, and China from the rest of the world. It cr...

  7. Development of Thick-foil and Fine-pitch GEMs with a Laser Etching Technique

    CERN Document Server

    Tamagawa, T; Asami, F; Abe, K; Iwamoto, S; Nakamura, S; Hayato, A; Iwahashi, T; Konami, S; Hamagaki, H; Yamaguchi, Y L; Tawara, H; Makishima, K; 10.1016/j.nima.2009.07.014

    2009-01-01

    We have produced thick-foil and fine-pitch gas electron multipliers (GEMs) using a laser etching technique. To improve production yield we have employed a new material, Liquid Crystal Polymer, instead of polyimide as an insulator layer. The effective gain of the thick-foil GEM with a hole pitch of 140 um, a hole diameter of 70 um, and a thickness of 100 um reached a value of 10^4 at an applied voltage of 720 V. The measured effective gain of the thick-foil and fine-pitch GEM (80 um pitch, 40 um diameter, and 100 um thick) was similar to that of the thick-foil GEM. The gain stability was measured for the thick-foil and fine-pitch GEM, showing no significant increase or decrease as a function of elapsed time from applying the high voltage. The gain stability over 3 h of operation was about 0.5%. Gain mapping across the GEM showed a good uniformity with a standard deviation of about 4%. The distribution of hole diameters across the GEM was homogeneous with a standard deviation of about 3%. There was no clear cor...

  8. How Complete is the ISC-GEM Global Earthquake Catalog?

    Science.gov (United States)

    Michael, A. J.

    2013-12-01

    In January, 2013, the International Seismological Centre (ISC), in collaboration with the Global Earthquake Model (GEM) effort, released a new global earthquake catalog, covering the time period from 1900 through the end of 2009. The ISC-GEM catalog effort made substantial improvements over existing catalogs by adding new phase data, relocating all events using one method, and reviewing and revising magnitudes. In order to use this catalog for global earthquake studies, I determined the magnitude of completeness (Mc) as a function of time. First, I divided the catalog into 7 time periods based on major changes in catalog processing and data availability. For each time period, I used 4 objective methods to determine Mc, with uncertainties determined by non-parametric bootstrapping. Due to differences between the 4 methods, the final Mc was determined subjectively by examining the features that each method focused on in both the cumulative and binned magnitude frequency distributions (MFD). Features which were subjectively rejected as correct Mc determinations included complications in the MFD at high magnitudes well above a linear portion of the MFD, large curvature of the MFD at magnitudes below smaller curvatures, and changes in the MFD that were actually in an increase above a Gutenberg-Richter distribution with decreasing magnitude. The high end of the bootstrap confidence range was preferred so that there is 95% confidence that Mc is not underestimated. The time periods and Mc values are: 1900-1917, Mc=7.7; 1918-1939 Mc=6.8; 1940-1954, Mc=6.8; 1955-1963, Mc=6.5; 1964-1975, Mc=6.0; 1976-2003, Mc=5.8; and 2004-2009, Mc=5.7. Using these Mc values for the longest time periods they are valid for (e.g. 1918-2009, 1940-2009,...) the data fits a Gutenberg-Richter relationship with b=1.0 and a=8.3, within 1 std. dev, with no declustering. The exception is for time periods that include 1900-1917 in which there are only 28 events with M≥Mc and the largest event is only

  9. An Approach from Knowledge Dust to Gems (Knowledge Management

    Directory of Open Access Journals (Sweden)

    Praveen Kumar

    2011-01-01

    Full Text Available Problem statement: Most businesses rely on the fact that their employees possess relevant knowledge and that they can apply it to the task at hand. The problem is that this knowledge is not owned by the organization. It is owned and controlled by its employees. Maintaining an appropriate level of knowledge in the organization is a very important issue. It is, however, not an easy task for most organizations and it is particularly problematic for software organizations, which are human and knowledge intensive. Knowledge management is a relatively new area that has attempted to address these problems. Conclusion/Recommendations: This study introduces an approach called the Knowledge Dust to Gems approach. This approach addresses some of the issues with knowledge management by providing low-barrier mechanisms to “jump start” the experience base. This approach allows the experience base to become more useful more quickly than traditional approaches.

  10. Operation of a GEM-TPC with pixel readout

    CERN Document Server

    Brezina, C; Kaminski, J; Killenberg, M; Krautscheid, T

    2012-01-01

    A prototype time projection chamber with 26 cm drift length was operated with a short-spaced triple gas electron multiplier (GEM) stack in a setup triggering on cosmic muon tracks. A small part of the anode plane is read out with a CMOS pixel application-specified integrated circuit (ASIC) named Timepix, which provides ultimate readout granularity. Pixel clusters of charge depositions corresponding to single primary electrons are observed and analyzed to reconstruct charged particle tracks. A dataset of several weeks of cosmic ray data is analyzed. The number of clusters per track length is well described by simulation. The obtained single point resolution approaches 50 m at short drift distances and is well reproduced by a simple model of single-electron diffusion.

  11. Development of Thick-foil and Fine-pitch GEMs with a Laser Etching Technique

    OpenAIRE

    Tamagawa, T.; Asami, F.; Abe, K.; Iwamoto, S.; Nakamura, S.; Hayato, A.; Iwahashi, T.; Konami, S.; Hamagaki, H.; Yamaguchi, Y. L.; Tawara, H.; Makishima, K.

    2009-01-01

    We have produced thick-foil and fine-pitch gas electron multipliers (GEMs) using a laser etching technique. To improve production yield we have employed a new material, Liquid Crystal Polymer, instead of polyimide as an insulator layer. The effective gain of the thick-foil GEM with a hole pitch of 140 um, a hole diameter of 70 um, and a thickness of 100 um reached a value of 10^4 at an applied voltage of 720 V. The measured effective gain of the thick-foil and fine-pitch GEM (80 um pitch, 40 ...

  12. Thermal neutron response of a boron-coated GEM detector via GEANT4 Monte Carlo code.

    Science.gov (United States)

    Jamil, M; Rhee, J T; Kim, H G; Ahmad, Farzana; Jeon, Y J

    2014-10-22

    In this work, we report the design configuration and the performance of the hybrid Gas Electron Multiplier (GEM) detector. In order to make the detector sensitive to thermal neutrons, the forward electrode of the GEM has been coated with the enriched boron-10 material, which works as a neutron converter. A total of 5×5cm(2) configuration of GEM has been used for thermal neutron studies. The response of the detector has been estimated via using GEANT4 MC code with two different physics lists. Using the QGSP_BIC_HP physics list, the neutron detection efficiency was determined to be about 3%, while with QGSP_BERT_HP physics list the efficiency was around 2.5%, at the incident thermal neutron energies of 25meV. The higher response of the detector proves that GEM-coated with boron converter improves the efficiency for thermal neutrons detection.

  13. The status of the GEM project for CMS high-$\\eta$ muon system

    CERN Document Server

    Abbaneo, D; Armagnaud, C; Aspell, P; Assran, Y; Bally, S; Ban, Y; Barria, P; Benussi, L; Berzano, U; Bianco, S; Bos, J; Bunkowski, K; Cai, J; Chatelain, J.P; Christiansen, J; Colafranceschi, S; Colaleo, A; Conde Garcia, A; David, E; De Lentdecker, G; De Oliveira, R; De Robertis, G; Duarte Pinto, S; Ferry, S; Formenti, F; Franconi, L; Fruboes, T; Gutierrez, A; Hohlmann, M; Kamel, A.E; Karchin, P.E; Loddo, F; Maerschalk, T; Magazzù, G; Maggi, M; Marchioro, A; Marinov, A; Mehta, K; Merlin, J; Mohapatra, A; Moulik, T; Nemallapudi, M.V; Nuzzo, S; Oliveri, E; Piccolo, D; Postema, H; Radi, A; Raffone, G; Rodrigues, A; Ropelewski, L; Saviano, G; Sharma, A; Smilkjovic, N; Staib, M.J; Teng, H; Tupputi, S.A; Turini, N; Tytgat, M; Villa, M; Yang, Y; Zaganidis, N; Zenoni, F; Zientek, M

    2013-01-01

    The dedicated CMS R&D program was intended to study the feasibility of using micropattern detectors for the instrumentation of the vacant j η j 4 1 : 6 region in the present Resistive Plate Chambers (RPCs) endcap system. The proposed detector for CMS is a Triple-Gas Electron Multiplier (GEM) trapezoidal chamber, equipped with 1D readout. While during 2010 – 2011 the Collaboration worked on the prototyping of the detector, during the fi rst part of 2012 a newly developed assembly technique to be used for the mass production was adopted. GEMs can provide precision tracking and fast trigger information, contributing on one hand to the improvement of the CMS muon Trigger and on the other hand to provide the missing redundancy in the high η region. In the view of the next LHC long shutdown (LS1) the CMS GEM Collaboration designed and built four full-size Triple GEM-based muon detectors

  14. Quality control for the first large areas of triple GEM chambers for the CMS endcaps

    CERN Document Server

    Tytgat, Michael

    2015-01-01

    The CMS GEM collaboration plans to equip the very forward muon system with triple GEM detectors that can withstand the environment of the high-luminosity LHC. This project is at the final stages of R and D and moving to production. An unprecedented large area of several 100m2 are to be instrumented with GEM detectors which will be produced in six different sites around the world. A common construction and quality control procedure is required to ensure the performance of each detector. The quality control steps will include optical inspection, cleaning and baking of all materials and parts used to build the detector, leakage current tests of the GEM foils, high voltage tests, gas leak tests of the chambers and monitoring pressure drop vs. time, gain calibration to know the optimal operation region of the detector, gain uniformity tests, and studying the efficiency, noise and tracking performance of the detectors in a cosmic stand using scintillators.

  15. The gain in Thick GEM multipliers and its time-evolution

    International Nuclear Information System (INIS)

    In the context of a project to upgrade the gas photon detectors of COMPASS RICH-1, we have performed an R and D programme aimed to develop photon detectors based on multi-layer arrangements of thick GEM electron multipliers coupled to a CsI photoconverter. For this purpose, thick GEMs have been characterised in detail including the gain performance, its dependance on the geometrical parameters and its time-evolution, a feature exhibited by the gas detectors with open insulator surfaces. The variation due to this evolution drammatically depends on the parameters themselves. In the present article we summarise the outcomes of the studies dedicated to the thick GEM gain and its evolution versus time. We also include a qualitative model which accounts for the peculiar details of the observed thick GEM gain time-evolution

  16. Discriminating cosmic muon and x-ray based on rising time using GEM detector

    CERN Document Server

    Hui-Yin, Wu; Xiao-Dong, Wang; Xian-Ming, Zhang; Hui-Rong, Qi; Wei, Zhang; Ke-Yan, Wu; Bi-Tao, Hu; Yi, Zhang

    2015-01-01

    Gas electron multiplier(GEM) detector is used in Cosmic Muon Scattering Tomography and neutron imaging in the last decade. In this work, a triple GEM device with an effective readout area of 10 cm X 10 cm is developed, and an experiment of discriminating between cosmic muon and x-ray based on rising time is tested. The energy resolution of GEM detector is tested by 55Fe ray source to prove the GEM detector has a good performance. The analysis of the complete signal-cycles allows to get the rising time and pulse heights. The experiment result indicates that cosmic muon and x-ray can be discriminated with an appropriate rising time threshold.

  17. Thermal neutron response of a boron-coated GEM detector via GEANT4 Monte Carlo code.

    Science.gov (United States)

    Jamil, M; Rhee, J T; Kim, H G; Ahmad, Farzana; Jeon, Y J

    2014-10-22

    In this work, we report the design configuration and the performance of the hybrid Gas Electron Multiplier (GEM) detector. In order to make the detector sensitive to thermal neutrons, the forward electrode of the GEM has been coated with the enriched boron-10 material, which works as a neutron converter. A total of 5×5cm(2) configuration of GEM has been used for thermal neutron studies. The response of the detector has been estimated via using GEANT4 MC code with two different physics lists. Using the QGSP_BIC_HP physics list, the neutron detection efficiency was determined to be about 3%, while with QGSP_BERT_HP physics list the efficiency was around 2.5%, at the incident thermal neutron energies of 25meV. The higher response of the detector proves that GEM-coated with boron converter improves the efficiency for thermal neutrons detection. PMID:25464183

  18. Testing of large real-size GEM detector for CBM experiment

    International Nuclear Information System (INIS)

    Gas Electron Multiplier (GEM) detector has been extensively used in many experiments for its excellent performance as a tracking detector. In CBM experiment, Muon Chamber detector (MUCH) for tracking muon, will be built using GEM based detector technology. In this direction several R and D has been performed with small to medium size triple GEM chambers. A real-size triple GEM detector proto-type, suitable for 1st detector station of MUCH detector, has been tested using high intensity proton beam of momentum 2.36 GeV/c at COSY, Germany. We get efficiency of detector >95 % at Δ VGEM = 371: 85 V. The variation of efficiency of the detector with rate of incoming particle is within 1%. The detector shows a gain of 3509 at ∆ Vgem = 375.18 Volt. The gain is stable with high rate of incoming particles with a small variation (∼9%)

  19. Der klinische Stellenwert der Polysomnographie bei Kindern mit kraniofazialen Fehlbildungssyndromen

    OpenAIRE

    Hein, Astrid

    2008-01-01

    Schlaf- und nächtliche Atemstörungen sind ein häufiges Symptom bei Kindern mit kraniofazialen Fehlbildungen, da es durch die Mittelgesichtshypoplasie zu einer Einengung der Atemwege kommen kann. Wir haben bei 28 Kindern Polysomnographien vorgenommen, um differenziertere Aussagen über die Art der schlafbezogenen Apnoen, den Zusammenhang mit bestimmten Schlafstadien und Schlafarchitektur und Korrelationen mit der mental-kognitiven Entwicklung sowie der Lebensqualität machen zu können. Diese wur...

  20. Stahlbetonplatten verstärkt mit Textilbeton unter Brandbelastung

    OpenAIRE

    Ehlig, Daniel; Jesse, Frank; Curbach, Manfred

    2009-01-01

    Im Rahmen experimenteller Untersuchungen wurden Stahlbetonplatten hergestellt, mit verschiedenen textilen Bewehrungen verstärkt, mit 125 % Gebrauchslast vorgeschädigt und anschließend unter Gebrauchslast mit einer Brandbelastung nach der Einheitstemperaturkurve (ISO-834, Cellulosic curve) beaufschlagt. Alle Platten hielten der Brandbelastung bei gleichzeitiger Biegebeanspruchung mehr als 60 Minuten stand und zeigten weder Betonabplatzungen noch andere optische Schädigungen auf. Die für dieses...

  1. 16 CFR 23.25 - Misuse of the word “gem.”

    Science.gov (United States)

    2010-01-01

    ... 16 Commercial Practices 1 2010-01-01 2010-01-01 false Misuse of the word âgem.â 23.25 Section 23... JEWELRY, PRECIOUS METALS, AND PEWTER INDUSTRIES § 23.25 Misuse of the word “gem.” (a) It is unfair or deceptive to use the word “gem” to describe, identify, or refer to a ruby, sapphire, emerald, topaz,...

  2. Development of triple GEM detector for a heavy ion physics experiment

    International Nuclear Information System (INIS)

    Building and testing of micro-pattern gas detector such as Gas Electron Multiplier (GEM) for several upcoming High-Energy Physics (HEP) experiment projects, is an advance area of research in the field of detector development. We have carried out the long-term stability test and the uniformity of the relative gain over a GEM detector. The method of long-term test and uniformity of the relative gain and the results are presented in this article

  3. BoNuS: Development and Use of a Radial TPC using Cylindrical GEMs

    Energy Technology Data Exchange (ETDEWEB)

    Howard Fenker; Nathan Baillie; Peter Bradshaw; S. Bultmann; Stephen Bueltmann; Volker Burkert; Michael Christy; Gail Dodge; Dipangkar Dutta; Rolf Ent; Josh Evans; Robert Fersch; Kevin Giovanetti; Keith Griffioen; Mikayel Ispiryan; Chandana Jayalath; Narbe Kalantarians; Cynthia Keppel; Sebastian Kuhn; Gabriel Niculescu; Maria-Ioana Niculescu; Svyatoslav Tkachenko; Vladas Tvaskis; Jixie Zhang

    2007-11-28

    To provide new access to information about nucleon structure from electron-neutron interactions, a specialized aystem of target and detector was developed at Jefferson Lab. It allows identification and measurement of spectator protons produced in e X scattering events. The detector is a radial time-projection chamber optimized for the acceptance of low-momentum protons. Gas gain is provided by three cascaded curved Gas Electron Multipliers (GEMs), the first application of GEMs in any configuration other than flat.

  4. [Bernt Ahrenholz : Verweise mit Demonstrativa im Gesprochenen Deutsch...] / Klaus Geyer

    Index Scriptorium Estoniae

    Geyer, Klaus

    2008-01-01

    Arvustus: Ahrenholz, Bernt. Verweise mit Demonstrativa im gesprochenen Deutsch : Grammatik, Zweitspracherwerb und Deutsch als Fremdsprache. Berlin ; New York : de Gruyter, 2007. (Linguistik - Impulse & Tendenzen ; 17)

  5. iGEMS: an integrated model for identification of alternative exon usage events.

    Science.gov (United States)

    Sood, Sanjana; Szkop, Krzysztof J; Nakhuda, Asif; Gallagher, Iain J; Murie, Carl; Brogan, Robert J; Kaprio, Jaakko; Kainulainen, Heikki; Atherton, Philip J; Kujala, Urho M; Gustafsson, Thomas; Larsson, Ola; Timmons, James A

    2016-06-20

    DNA microarrays and RNAseq are complementary methods for studying RNA molecules. Current computational methods to determine alternative exon usage (AEU) using such data require impractical visual inspection and still yield high false-positive rates. Integrated Gene and Exon Model of Splicing (iGEMS) adapts a gene-level residuals model with a gene size adjusted false discovery rate and exon-level analysis to circumvent these limitations. iGEMS was applied to two new DNA microarray datasets, including the high coverage Human Transcriptome Arrays 2.0 and performance was validated using RT-qPCR. First, AEU was studied in adipocytes treated with (n = 9) or without (n = 8) the anti-diabetes drug, rosiglitazone. iGEMS identified 555 genes with AEU, and robust verification by RT-qPCR (∼90%). Second, in a three-way human tissue comparison (muscle, adipose and blood, n = 41) iGEMS identified 4421 genes with at least one AEU event, with excellent RT-qPCR verification (95%, n = 22). Importantly, iGEMS identified a variety of AEU events, including 3'UTR extension, as well as exon inclusion/exclusion impacting on protein kinase and extracellular matrix domains. In conclusion, iGEMS is a robust method for identification of AEU while the variety of exon usage between human tissues is 5-10 times more prevalent than reported by the Genotype-Tissue Expression consortium using RNA sequencing. PMID:27095197

  6. Property of LCP-GEM in Pure Dimethyl Ether at Low Pressure

    CERN Document Server

    Takeuchi, Y; Kitaguchi, T; Yamada, S; Iwakiri, W; Asami, F; Yoshikawa, A; Kaneko, K; Enoto, T; Hayato, A; Kohmura, T

    2013-01-01

    We present a systematic investigation of the gain properties of a gas electron multiplier (GEM) foil in pure dimethyl ether (DME) at low pressures. The GEM is made from copper- clad liquid crystal polymer insulator (LCP-GEM) designed for space use, and is applied to a time projection chamber filled with low-pressure DME gas to observe the linear polarization of cosmic X-rays. We have measured gains of a 100 um-thick LCP-GEM as a function of the voltage between GEM electrodes at various gas pressures ranging from 10 to 190 Torr with 6.4 keV X-rays. The highest gain at 190 Torr is about 2x10^4, while that at 20 Torr is about 500. We find that the pressure and electric-field dependence of the GEM gain is described by the first Townsend coefficient. The energy scale from 4.5 to 8.0 keV is linear with non-linearity of less than 1.4% above 30 Torr.

  7. Investigation of GEM-Micromegas detector on X-ray beam of synchrotron radiation

    Science.gov (United States)

    Zhang, Yu-Lian; Qi, Hui-Rong; Hu, Bi-Tao; Fan, Sheng-Nan; Wang, Bo; Liu, Mei; Zhang, Jian; Liu, Rong-Guang; Chang, Guang-Cai; Liu, Peng; Ouyang, Qun; Chen, Yuan-Bo; Yi, Fu-Ting

    2014-04-01

    To reduce the discharge of the standard bulk Micromegas and GEM detectors, a GEM-Micromegas detector was developed at the Institute of High Energy Physics. Taking into account the advantages of the two detectors, one GEM foil was set as a preamplifier on the mesh of Micromegas in the structure and the GEM preamplification decreased the working voltage of Micromegas to significantly reduce the effect of the discharge. At the same gain, the spark probability of the GEM-Micromegas detector can be reduced to a factor 0.01 compared to the standard Micromegas detector, and an even higher gain could be obtained. This paper describes the performance of the X-ray beam detector that was studied at 1W2B Laboratory of Beijing Synchrotron Radiation Facility. Finally, the result of the energy resolution under various X-ray energies was given in different working gases. This indicates that the GEM-Micromegas detector has an energy response capability in an energy range from 6 keV to 20 keV and it could work better than the standard bulk-Micromegas.

  8. Properties of thick GEM in low-pressure deuterium

    International Nuclear Information System (INIS)

    Deuteron inelastic scattering (d, d') provides a promising spectroscopic tool to study nuclear incompressibility. In studies of deuteron inelastic scattering of unstable nuclei, measurements of low-energy recoiled particles is very important. In order to perform these measurements, we are developing a GEM-TPC based gaseous active target, called CAT (Center for nuclear study Active Target), operated with pure deuterium gas. The CAT has been tested with deuterium gas at 1 atm and 100-μm-thick GEMs. The low-pressure operation of CAT is planned in order to improve the detection capability for lower-energy recoil particles. A 400 μm-thick gas electron multiplier (THGEM) was chosen for the low-pressure operation of CAT. However, the properties of THGEM in low-pressure deuterium are currently undocumented. In this work, the performance of THGEM with low-pressure pure deuterium gas has been investigated. The effective gas gain of THGEM has been measured in various conditions using a 5.5-MeV 241Am alpha source. The effective gas gain was measured for 0.2-, 0.3- and 0.4-atm deuterium gas and a gas gain of about 103 was achieved by a double THGEM structure at 0.2 atm. The maximum achieved gain decreased with increasing gas pressure. The dependences of the effective gas gain on the electric field strengths of the drift, transfer and induction regions were investigated. The gain stability as a function of time in hydrogen gas was also tested and a relaxation time of THGEM of about 60 hours was observed with a continuous irradiation of alpha particles, which is significantly longer than previous studies have reported. We have tried to evaluate the gas gain of THGEM in deuterium gas by considering only the Townsend ionization process; however, it turned out that more phenomenological aspects, such as transfer efficiency, should be included in the evaluation. The basic properties of THGEM in low-pressure deuterium have been investigated for the first time

  9. GEM*STAR: Time for an Alternative Way Forward

    Science.gov (United States)

    Vogelaar, R. Bruce

    2011-10-01

    The presumption that nuclear reactors will retain their role in global energy production is constantly being challenged - even more so following recent events at Fukushima. Nuclear energy, despite being ``green,'' has inexorably been coupled in the public mind with three paramount concerns: safety, weapons proliferation, and waste (and then ultimately cost). Over the past four decades, the safety of deployed fleets has greatly improved, yet the capital and political costs of a ``nuclear energy option'' appear insurmountable in several countries. The US approach to civilian nuclear energy has become deeply entrenched, first through choices made by the military, and then by the deployed nuclear reactor fleet. This extends to the research agencies as well, to the point where basic sciences and nuclear energy operate in separate spheres. But technologies and priorities have changed, and the time has arrived where a transformative re-think of nuclear energy is not only possible, but urgent. And nuclear physicists are uniquely positioned to accomplish this. This talk will show that by asking, and answering,``what would an accelerator-driven civilian nuclear energy program look like,'' ADNA Corporation's GEM*STAR design directly addresses all three fundamental concerns: safety, proliferation, and waste - and also the final hurdle: cost. GEM*STAR is not an ``add-on'' (to either Project-X, or GEN III+), but rather a base-line energy production capacity, for either electricity or transport fuel production. It integrates and advances the molten-salt reactor technology developed at ORNL, the MW beam accelerator technologies developed by basic sciences, and a reactor/target design optimized for accelerator driven-systems. The results include: the ability to use LWR spent fuel without reprocessing or additional waste; the ability to use natural uranium; no critical mass ever present; orders-of-magnitude less volatile radioactivity in the core; more efficient use of, and deeper

  10. Evaluation of ozone profile and tropospheric ozone retrievals from GEMS and OMI spectra

    Directory of Open Access Journals (Sweden)

    J. Bak

    2013-02-01

    Full Text Available South Korea is planning to launch the GEMS (Geostationary Environment Monitoring Spectrometer instrument into the GeoKOMPSAT (Geostationary Korea Multi-Purpose SATellite platform in 2018 to monitor tropospheric air pollutants on an hourly basis over East Asia. GEMS will measure backscattered UV radiances covering the 300–500 nm wavelength range with a spectral resolution of 0.6 nm. The main objective of this study is to evaluate ozone profiles and stratospheric column ozone amounts retrieved from simulated GEMS measurements. Ozone Monitoring Instrument (OMI Level 1B radiances, which have the spectral range 270–500 nm at spectral resolution of 0.42–0.63 nm, are used to simulate the GEMS radiances. An optimal estimation-based ozone profile algorithm is used to retrieve ozone profiles from simulated GEMS radiances. Firstly, we compare the retrieval characteristics (including averaging kernels, degrees of freedom for signal, and retrieval error derived from the 270–330 nm (OMI and 300–330 nm (GEMS wavelength ranges. This comparison shows that the effect of not using measurements below 300 nm on retrieval characteristics in the troposphere is insignificant. However, the stratospheric ozone information in terms of DFS decreases greatly from OMI to GEMS, by a factor of ∼2. The number of the independent pieces of information available from GEMS measurements is estimated to 3 on average in the stratosphere, with associated retrieval errors of ~1% in stratospheric column ozone. The difference between OMI and GEMS retrieval characteristics is apparent for retrieving ozone layers above ~20 km, with a reduction in the sensitivity and an increase in the retrieval errors for GEMS. We further investigate whether GEMS can resolve the stratospheric ozone variation observed from high vertical resolution Earth Observing System (EOS Microwave Limb Sounder (MLS. The differences in stratospheric ozone profiles between GEMS and MLS are comparable to those

  11. First performance of the gems + gmos system. Part1. Imaging

    CERN Document Server

    Hibon, Pascale; Neichel, Benoit; Prout, Benjamin; Rigaut, Francois; Koning, Alice; Carrasco, Eleazar R; Gimeno, German; Pessev, Peter

    2016-01-01

    During the commissioning of the Gemini MCAO System (GeMS), we had the opportunity to obtain data with the Gemini Multi-Object Spectrograph (GMOS), the most utilised instrument at Gemini South Observatory, in March and May 2012. Several globular clusters were observed in imaging mode that allowed us to study the performance of this new and untested combination. GMOS is a visible instrument, hence pushing MCAO toward the visible.We report here on the results with the GMOS instruments, derive photometric performance in term of Full Width Half Maximum (FWHM) and throughput. In most of the cases, we obtained an improvement factor of at least 2 against the natural seeing. This result also depends on the Natural Guide Star constellation selected for the observations and we then study the impact of the guide star selection on the FWHM performance.We also derive a first astrometric analysis showing that the GeMS+GMOS system provide an absolute astrometric precision better than 8mas and a relative astrometric precision...

  12. Radiation tests for a single-GEM-loaded gaseous detector

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyong Sei; Hong, Byung Sik; Park, Sung Keun [Korea University, Seoul (Korea, Republic of); Kim, Sang Yeol [NoticeKorea, Anyang (Korea, Republic of)

    2014-11-15

    We report on a systematic study of a single-gas-electron-multiplier (GEM)-loaded gaseous detector developed for precision measurements of high-energy particle beams and for dose verification in particle therapy. In the present study, a 256-channel prototype detector having an active area of 16 x 16 cm{sup 2} and operating using a continuous current-integration-mode signal-processing method was manufactured and tested with X-rays emitted from a 70-kV X-ray generator and 43-MeV protons provided by the MC50 proton cyclotron at the Korea Institute of Radiological and Medical Science(KIRAMS). The amplified detector response was measured for X-rays with an intensity of about 5 x 10{sup 6} Hz cm{sup -2}. The linearity of the detector response to the particle flux was examined and validated by using 43-MeV proton beams. The non-uniform development of the amplification for the gas electrons in space was corrected by applying a proper calibration to the channel responses of the measured beam-profile data. We conclude from the radiation tests that the detector developed in the present study will allow us to perform quality measurements of various high-energy particle beams and to apply the technology to dose-verification measurements in particle therapy.

  13. An Interactive Java Statistical Image Segmentation System: GemIdent

    Directory of Open Access Journals (Sweden)

    Susan Holmes

    2009-06-01

    Full Text Available Supervised learning can be used to segment/identify regions of interest in images usingboth color and morphological information. A novel object identication algorithm wasdeveloped in Java to locate immune and cancer cells in images of immunohistochemically-stained lymph node tissue from a recent study published by Kohrt et al. (2005. Thealgorithms are also showing promise in other domains. The success of the method de-pends heavily on the use of color, the relative homogeneity of object appearance and oninteractivity. As is often the case in segmentation, an algorithm specically tailored tothe application works better than using broader methods that work passably well on anyproblem. Our main innovation is the interactive feature extraction from color images. Wealso enable the user to improve the classication with an interactive visualization system.This is then coupled with the statistical learning algorithms and intensive feedback fromthe user over many classication-correction iterations, resulting in a highly accurate anduser-friendly solution. The system ultimately provides the locations of every cell recog-nized in the entire tissue in a text le tailored to be easily imported into R (Ihaka andGentleman 1996; R Development Core Team 2009 for further statistical analyses. Thisdata is invaluable in the study of spatial and multidimensional relationships between cellpopulations and tumor structure. This system is available at http://www.GemIdent.com/together with three demonstration videos and a manual.

  14. Radiation Tests for a Single-GEM Loaded Gaseous Detector

    CERN Document Server

    Lee, Kyong Sei; Kim, Sang Yeol; Park, Sung Keun

    2014-01-01

    We report on the systematic study of a single-gas-electron-multiplication (GEM) loaded gaseous detector developed for precision measurements of high-energy particle beams and dose-verification measurements. In the present study, a 256-channel prototype detector with an active area of 16$\\times$16 cm$^{2}$, operated in a continuous current-integration-mode signal-processing method, was manufactured and tested with x rays emitted from a 70-kV x-ray generator and 43-MeV protons provided by the MC50 proton cyclotron at the Korea Institute of Radiological and Medical Science (KIRAMS). The amplified detector response was measured for the x rays with an intensity of about 5$\\times$10$^{6}$ Hz cm$^{-2}$. The linearity of the detector response to the particle flux was examined and validated by using 43-MeV proton beams. The non-uniform development of the amplification for the gas electrons in space was corrected by applying proper calibration to the channel responses of the measured beam-profile data. We concluded fro...

  15. Quality Control (QC2) of Gas Electron Multiplier (GEM) for GE1/1 at CMS Experiment

    CERN Document Server

    Sharma, Archana

    2016-01-01

    Gas Electron Multiplier (GEM) is a gas ionization detector that detect charged particles and will be implemented on CMS system. It is designed to improve muon trigger and tracking performance at high luminosity after the second Long Shutdown (LS2). For my project, GEM foils, a component of the Triple GEM detector have been studied. In order to pass the test, the foils need to run in the Fast Test and Long Test of QC2.

  16. Tissue Velocity, Strain und Strain Rate bei Hunden mit Mitralklappenendokardiose

    OpenAIRE

    Javornik, Ana

    2007-01-01

    In der vorliegenden Arbeit „Tissue Velocity, Strain und Strain Rate bei Hunden mit Mitralklappenendokardiose“ wurden erstmals die Geschwindigkeits- und Verformungsparameter zur Evaluierung von Hunden mit Mitralklappenendokardiose angewendet. Diese erweisen sich als neue und viel versprechende Möglichkeiten zur Quantifizierung der regionalen Myokardfunktion. Die myokardialen Funktionsparameter finden in der Humanmedizin weit verbreitete Anwendung und auch in der Tiermedizin erlangen sie zunehm...

  17. Mice deficient in GEM GTPase show abnormal glucose homeostasis due to defects in beta-cell calcium handling.

    Directory of Open Access Journals (Sweden)

    Jenny E Gunton

    Full Text Available AIMS AND HYPOTHESIS: Glucose-stimulated insulin secretion from beta-cells is a tightly regulated process that requires calcium flux to trigger exocytosis of insulin-containing vesicles. Regulation of calcium handling in beta-cells remains incompletely understood. Gem, a member of the RGK (Rad/Gem/Kir family regulates calcium channel handling in other cell types, and Gem over-expression inhibits insulin release in insulin-secreting Min6 cells. The aim of this study was to explore the role of Gem in insulin secretion. We hypothesised that Gem may regulate insulin secretion and thus affect glucose tolerance in vivo. METHODS: Gem-deficient mice were generated and their metabolic phenotype characterised by in vivo testing of glucose tolerance, insulin tolerance and insulin secretion. Calcium flux was measured in isolated islets. RESULTS: Gem-deficient mice were glucose intolerant and had impaired glucose stimulated insulin secretion. Furthermore, the islets of Gem-deficient mice exhibited decreased free calcium responses to glucose and the calcium oscillations seen upon glucose stimulation were smaller in amplitude and had a reduced frequency. CONCLUSIONS: These results suggest that Gem plays an important role in normal beta-cell function by regulation of calcium signalling.

  18. MIT 12 TESLA coil experimental results

    International Nuclear Information System (INIS)

    The MIT 12 tesla coil was fabricated using a 486-strand bronze-matrix Nb3Sn, JBK-75 superalloy sheathed Internally Cooled Cabled Superconductor (ICCS). The rectangularly shaped ICCS conductor was wound into three double pancakes prior to a six-day reaction (4 days at 7000C followed by 2 days at 7300C). Prior to installation in the High Field Test Facility (HFTF) at LLNL the three subcoils were insulated and epoxy potted. With the HFTF providing a 9 T background field, the test coil was used to raise the central field up to 12 T. Measurements of critical current are reported for fields in the 11 to 12 T range for temperatures of 4.2, 5.2 and 7.5 K with supercritical as well as 1 atm, two-phase internal helium. Steady-state, inductively heated as well as quench induced operations are described

  19. Multiple Mittelwertvergleiche - parametrisch und nichtparametrisch - sowie α-Adjustierungen mit praktischen Anwendungen mit R und SPSS

    OpenAIRE

    Lüpsen, Haiko

    2014-01-01

    Die etwa 20 bekanntesten parametrischen und ca. 10 nichtparametrischen Verfahren für multiple Mittelwertvergleiche sowie ca. 20 Methoden für alpha-Korrekturen bei Paarvergleichen werden vorgestellt. Dabei stehen solche im Vordergrund, die in R und/oder in SPSS ohne großen Aufwand anwendbar sind. Es werden die Voraussetzungen der Verfahren besprochen sowie Lösungen mit R und SPSS ausführlich gezeigt.

  20. Teaching ``The Physics of Energy'' at MIT

    Science.gov (United States)

    Jaffe, Robert

    2009-05-01

    New physics courses on energy are popping up at colleges and universities across the country. Many require little or no previous physics background, aiming to introduce a broad audience to this complex and critical problem, often augmenting the scientific message with economic and policy discussions. Others are advanced courses, focussing on highly specialized subjects like solar voltaics, nuclear physics, or thermal fluids, for example. About two years ago Washington Taylor and I undertook to develop a course on the ``Physics of Energy'' open to all MIT students who had taken MIT's common core of university level calculus, physics, and chemistry. By avoiding higher level prerequisites, we aimed to attract and make the subject relevant to students in the life sciences, economics, etc. --- as well as physical scientists and engineers --- who want to approach energy issues in a sophisticated and analytical fashion, exploiting their background in calculus, mechanics, and E & M, but without having to take advanced courses in thermodynamics, quantum mechanics, or nuclear physics beforehand. Our object was to interweave teaching the fundamental physics principles at the foundations of energy science with the applications of those principles to energy systems. We envisioned a course that would present the basics of statistical, quantum, and fluid mechanics at a fairly sophisticated level and apply those concepts to the study of energy sources, conversion, transport, losses, storage, conservation, and end use. In the end we developed almost all of the material for the course from scratch. The course debuted this past fall. I will describe what we learned and what general lessons our experience might have for others who contemplate teaching energy physics broadly to a technically sophisticated audience.

  1. 10 MeV Electron Beam Test Using Gas Electron Multiplier (GEM) Detectors

    Science.gov (United States)

    Hahn, C. H.; Kim, I. G.; Park, S. T.; Kim, W. J.; Yoo, D. S.; Moon, B. S.; Ha, S. Y.; Ahn, B. J.; Ha, Y. J.; Jung, C. Y.; Jung, S. H.; Cho, B. H.; Lee, B. C.; Han, Y. H.; Chung, C. E.; Li, J.; White, A. P.; Yu, J.

    2006-10-01

    10 MeV electron beam has been tested using a single channel double gas electron multiplier (GEM) detector constructed by Changwon National University and a multi-channel double GEM chamber by the University of Texas at Arlington. It has been demonstrated that both detectors are able to detect signals generated by high energy electrons as well as x-rays. By analyzing the chamber output signals captured by oscilloscope, it is believed that the x-ray was produced by bremsstrahlung while electrons were decelerating in a 2 mm lead plate. The time profile of the KAERI's 10 MeV electron beam bunches was determined based on the calculated angular distribution of electrons by multiple scattering in the lead plate. Furthermore, the spatial electron density distribution has been extrapolated by using the time profile. The effective gain of the GEM chamber has been estimated by analyzing the measured output currents of the chamber. It is important that the time and spatial profiles of the high energy electron beam could be determined using GEM detectors, which suggests that GEM might have an application as a calorimeter for a large scale accelerator. Details of experimental procedure will be discussed.

  2. Thermal neutron response of a boron-coated GEM detector via GEANT4 Monte Carlo code

    International Nuclear Information System (INIS)

    In this work, we report the design configuration and the performance of the hybrid Gas Electron Multiplier (GEM) detector. In order to make the detector sensitive to thermal neutrons, the forward electrode of the GEM has been coated with the enriched boron-10 material, which works as a neutron converter. A total of 5×5 cm2 configuration of GEM has been used for thermal neutron studies. The response of the detector has been estimated via using GEANT4 MC code with two different physics lists. Using the QGSPBICHP physics list, the neutron detection efficiency was determined to be about 3%, while with QGSPBERTHP physics list the efficiency was around 2.5%, at the incident thermal neutron energies of 25 meV. The higher response of the detector proves that GEM-coated with boron converter improves the efficiency for thermal neutrons detection. - Highlights: • The results of boron-coated GEM for thermal neutrons are described. • The simulations were performed by GEANT4 MC code. • The evaluation was determined by GEANT4 using two physics lists. • The response of the detector was taken for En=25–100 meV

  3. The geology, mineralogy and rare element geochemistry of the gem deposits of Sri Lanka

    Directory of Open Access Journals (Sweden)

    C. B. Dissanayake

    2000-01-01

    Full Text Available The gem deposits of Sri Lanka are studied from the point of view of their geology, mineralogy and geochemistry. Nearly all the gem formations are located in the central high-grade metamorphic terrain of the Highland Complex. The gem deposits are classified as sedimentary, metamorphic and magmatic; the sedimentary types being the most abundant. The mineralogy of the gem deposits varies widely with, among others, corundum, chrysoberyl, beryl, spinel, topaz,zircon, tourmaline, garnet and sphene being common.Rare element concentrations in sediments from the three main gem fields of Sri Lanka, namely Ratnapura, Elahera and Walawe, were studied. It was found that some sediments are considerably enriched in certain elements compared to their average continental crustal abundances. The Walawe Ganga sediments show anomalous enrichments of the high field strength and associated elements, particularly Zr, Hf, W and Ti. This is attributed to the presence of accessory mineralssuch as zircon, monazite and rutile. Some of these heavy minerals comprise as much as 50 wt% of sediment. The geochemical enrichment of some trace elements compared to their average crustal abundances indicates that highly differentiated granites and associated pegmatites have provided the source materials for enrichment.

  4. Gaseous elemental mercury (GEM emissions from snow surfaces in northern New York.

    Directory of Open Access Journals (Sweden)

    J Alexander Maxwell

    Full Text Available Snow surface-to-air exchange of gaseous elemental mercury (GEM was measured using a modified Teflon fluorinated ethylene propylene (FEP dynamic flux chamber (DFC in a remote, open site in Potsdam, New York. Sampling was conducted during the winter months of 2011. The inlet and outlet of the DFC were coupled with a Tekran Model 2537A mercury (Hg vapor analyzer using a Tekran Model 1110 two port synchronized sampler. The surface GEM flux ranged from -4.47 ng m(-2 hr(-1 to 9.89 ng m(-2 hr(-1. For most sample periods, daytime GEM flux was strongly correlated with solar radiation. The average nighttime GEM flux was slightly negative and was not well correlated with any of the measured meteorological variables. Preliminary, empirical models were developed to estimate GEM emissions from snow surfaces in northern New York. These models suggest that most, if not all, of the Hg deposited with and to snow is reemitted to the atmosphere.

  5. The HadGEM2 family of Met Office Unified Model Climate configurations

    Directory of Open Access Journals (Sweden)

    The HadGEM2 Development Team: Martin, G. M.

    2011-04-01

    Full Text Available We describe the HadGEM2 family of climate configurations of the Met Office Unified Model, MetUM. The concept of a model "family" comprises a range of specific model configurations incorporating different levels of complexity but with a common physical framework. The HadGEM2 family of configurations includes atmosphere and ocean components, with and without a vertical extension to include a well-resolved stratosphere, and an Earth-System (ES component which includes dynamic vegetation, ocean biology and atmospheric chemistry. The HadGEM2 physical model includes improvements designed to address specific systematic errors encountered in the previous climate configuration, HadGEM1, namely Northern Hemisphere continental temperature biases and tropical sea surface temperature biases and poor variability. Targeting these biases was crucial in order that the ES configuration could represent important biogeochemical climate feedbacks. Detailed descriptions and evaluations of particular HadGEM2 family members are included in a number of other publications, and the discussion here is limited to a summary of the overall performance using a set of model metrics which compare the way in which the various configurations simulate present-day climate and its variability.

  6. The HadGEM2 family of Met Office Unified Model climate configurations

    Directory of Open Access Journals (Sweden)

    The HadGEM2 Development Team: G. M. Martin

    2011-09-01

    Full Text Available We describe the HadGEM2 family of climate configurations of the Met Office Unified Model, MetUM. The concept of a model "family" comprises a range of specific model configurations incorporating different levels of complexity but with a common physical framework. The HadGEM2 family of configurations includes atmosphere and ocean components, with and without a vertical extension to include a well-resolved stratosphere, and an Earth-System (ES component which includes dynamic vegetation, ocean biology and atmospheric chemistry. The HadGEM2 physical model includes improvements designed to address specific systematic errors encountered in the previous climate configuration, HadGEM1, namely Northern Hemisphere continental temperature biases and tropical sea surface temperature biases and poor variability. Targeting these biases was crucial in order that the ES configuration could represent important biogeochemical climate feedbacks. Detailed descriptions and evaluations of particular HadGEM2 family members are included in a number of other publications, and the discussion here is limited to a summary of the overall performance using a set of model metrics which compare the way in which the various configurations simulate present-day climate and its variability.

  7. Experiments and analyses on reactivity worth of gas expansion module (GEM) in FCA XX-1. Joint research

    International Nuclear Information System (INIS)

    Gas Expansion Module (GEM) will be installed in large scale fast reactors in order to insert negative reactivity feedback in a transition of the primary pump trip. A mock-up experiment was performed at the XX-1 core of the Fast Critical Assembly (FCA) to evaluate and improve the prediction accuracy of the reactivity effect inserted by the GEM (GEM reactivity worth). The GEM was categorized into 'External GEM' and 'In-core GEM' according to its position; the experiment was performed for both cases, and the prediction accuracy was discussed. As for the external GEM reactivity worth, it was indicated that the self-shielding effect for iron used as the structural material of the GEM should be taken into account in the preparation process of the effective cross section of the GEM region. The overestimation of 10-20% was observed when the deterministic calculation was adopted for the transport correction in RZ geometry. When the Monte-Carlo method was used instead, the overestimation was reduced below 10%. As for the in-core GEM reactivity worth, it was pointed out that the cell homogenization should be carefully carried out since the neutron streaming affects the prediction accuracy. The prediction accuracy shows a dependence on the sodium level in the GEM. The prediction accuracy was evaluated by separating it into the non-leakage term and the leakage term by a least-squares fitting. It was found that the non-leakage term shows 10-20% overestimation, while the leakage term agrees well with the measurement within the experimental error. (author)

  8. Experiments and analyses on reactivity worth of gas expansion module (GEM) in FCA XX-1. Joint research

    Energy Technology Data Exchange (ETDEWEB)

    Oigawa, Hiroyuki; Andoh, Masaki; Iijima, Susumu [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Takaki, Naoyuki; Uematsu, Mari Marianne [The Japan Atomic Power Company, Tokyo (Japan)

    2001-06-01

    Gas Expansion Module (GEM) will be installed in large scale fast reactors in order to insert negative reactivity feedback in a transition of the primary pump trip. A mock-up experiment was performed at the XX-1 core of the Fast Critical Assembly (FCA) to evaluate and improve the prediction accuracy of the reactivity effect inserted by the GEM (GEM reactivity worth). The GEM was categorized into 'External GEM' and 'In-core GEM' according to its position; the experiment was performed for both cases, and the prediction accuracy was discussed. As for the external GEM reactivity worth, it was indicated that the self-shielding effect for iron used as the structural material of the GEM should be taken into account in the preparation process of the effective cross section of the GEM region. The overestimation of 10-20% was observed when the deterministic calculation was adopted for the transport correction in RZ geometry. When the Monte-Carlo method was used instead, the overestimation was reduced below 10%. As for the in-core GEM reactivity worth, it was pointed out that the cell homogenization should be carefully carried out since the neutron streaming affects the prediction accuracy. The prediction accuracy shows a dependence on the sodium level in the GEM. The prediction accuracy was evaluated by separating it into the non-leakage term and the leakage term by a least-squares fitting. It was found that the non-leakage term shows 10-20% overestimation, while the leakage term agrees well with the measurement within the experimental error. (author)

  9. Python based integration of GEM detector electronics with JET data acquisition system

    Science.gov (United States)

    Zabołotny, Wojciech M.; Byszuk, Adrian; Chernyshova, Maryna; Cieszewski, Radosław; Czarski, Tomasz; Dalley, Simon; Hogben, Colin; Jakubowska, Katarzyna L.; Kasprowicz, Grzegorz; Poźniak, Krzysztof; Rzadkiewicz, Jacek; Scholz, Marek; Shumack, Amy

    2014-11-01

    This paper presents the system integrating the dedicated measurement and control electronic systems for Gas Electron Multiplier (GEM) detectors with the Control and Data Acquisition system (CODAS) in the JET facility in Culham, England. The presented system performs the high level procedures necessary to calibrate the GEM detector and to protect it against possible malfunctions or dangerous changes in operating conditions. The system also allows control of the GEM detectors from CODAS, setting of their parameters, checking their state, starting the plasma measurement and to reading the results. The system has been implemented using the Python language, using the advanced libraries for implementation of network communication protocols, for object based hardware management and for data processing.

  10. Effect of Regrown Graphite on the Growth of Large Gem Diamonds by Temperature Gradient Method

    Institute of Scientific and Technical Information of China (English)

    ZANG Chuan-Yi; JIA Xiao-Peng; MA Hong-An; TIAN Yu; XIAO Hong-Yu

    2005-01-01

    @@ Generally, when growing high-quality large gem diamond crystals by temperature gradient method under high pressure and high temperature, the crystal growth rate is only determined by the temperature gradient. However,we find that the seed crystal cannot completely absorb all the diffused carbon sources, when growing gem diamonds under a higher temperature gradient. Other influence factors appear, and the growth rate of growing diamonds is partly dependent on the crystalline form of superfluous unabsorbed carbon source, flaky regrown graphite or small diamond crystals nucleated spontaneously. The present form is determined by the growth temperature if the pressure isfixed. Different from spontaneous diamond nuclei, the appearance of regrown graphite in the diamondstable region can retard the growth rate of gem diamonds substantially, even if the temperature gradient keeps unchanged. On the other hand, the formation mechanism of metastable regrown graphite in the diamond-stable region is also explained.

  11. Electron cyclotron resonance charge breeder ion source simulation by MCBC and GEM

    International Nuclear Information System (INIS)

    Numerical simulation results by the GEM and MCBC codes are presented, along with a comparison with experiments for beam capture dynamics and parameter studies of charge state distribution (CSD) of electron cyclotron resonance charge breeder ion sources. First, steady state plasma profiles are presented by GEM with respect to key experimental parameters such as rf power and gas pressure. As rf power increases, electron density increases by a small amount and electron energy by a large amount. The central electrostatic potential dip also increased. Next, MCBC is used to trace injected beam ions to obtain beam capture profiles. Using the captured ion profiles, GEM obtains a CSD of beam ions. As backscattering can be significant, capturing the ions near the center of the device enhances the CSD. The effect of rf power on the beam CSD is mainly due to different steady states plasmas. Example cases are presented assuming that the beam ions are small enough not to affect the plasma

  12. OSG-GEM: Gene Expression Matrix Construction Using the Open Science Grid.

    Science.gov (United States)

    Poehlman, William L; Rynge, Mats; Branton, Chris; Balamurugan, D; Feltus, Frank A

    2016-01-01

    High-throughput DNA sequencing technology has revolutionized the study of gene expression while introducing significant computational challenges for biologists. These computational challenges include access to sufficient computer hardware and functional data processing workflows. Both these challenges are addressed with our scalable, open-source Pegasus workflow for processing high-throughput DNA sequence datasets into a gene expression matrix (GEM) using computational resources available to U.S.-based researchers on the Open Science Grid (OSG). We describe the usage of the workflow (OSG-GEM), discuss workflow design, inspect performance data, and assess accuracy in mapping paired-end sequencing reads to a reference genome. A target OSG-GEM user is proficient with the Linux command line and possesses basic bioinformatics experience. The user may run this workflow directly on the OSG or adapt it to novel computing environments. PMID:27499617

  13. Developments and the preliminary tests of Resistive GEMs manufactured by a screen printing technology

    CERN Document Server

    Agócs, G; Oliveira, R; Martinego, P; Peskov, Vladimir; Pietropaolo, P; Picchi, P

    2008-01-01

    We report promising initial results obtained with new resistive-electrode GEM (RETGEM) detectors manufactured, for the first time, using screen printing technology. These new detectors allow one to reach gas gains nearly as high as with ordinary GEM-like detectors with metallic electrodes; however, due to the high resistivity of its electrodes the RETGEM, in contrast to ordinary hole-type detectors, has the advantage of being fully spark protected. We discovered that RETGEMs can operate stably and at high gains in noble gases and in other badly quenched gases, such as mixtures of noble gases with air and in pure air; therefore, a wide range of practical applications, including dosimetry and detection of dangerous gases, is foreseeable. To promote a better understanding of RETGEM technology some comparative studies were completed with metallic-electrode thick GEMs. A primary benefit of these new RETGEMs is that the screen printing technology is easily accessible to many research laboratories. This accessibilit...

  14. A COMSOL-GEMS interface for modeling coupled reactive-transport geochemical processes

    Science.gov (United States)

    Azad, Vahid Jafari; Li, Chang; Verba, Circe; Ideker, Jason H.; Isgor, O. Burkan

    2016-07-01

    An interface was developed between COMSOL MultiphysicsTM finite element analysis software and (geo)chemical modeling platform, GEMS, for the reactive-transport modeling of (geo)chemical processes in variably saturated porous media. The two standalone software packages are managed from the interface that uses a non-iterative operator splitting technique to couple the transport (COMSOL) and reaction (GEMS) processes. The interface allows modeling media with complex chemistry (e.g. cement) using GEMS thermodynamic database formats. Benchmark comparisons show that the developed interface can be used to predict a variety of reactive-transport processes accurately. The full functionality of the interface was demonstrated to model transport processes, governed by extended Nernst-Plank equation, in Class H Portland cement samples in high pressure and temperature autoclaves simulating systems that are used to store captured carbon dioxide (CO2) in geological reservoirs.

  15. Study of electron focusing in thick GEM based photon detectors using semitransparent photocathodes

    Energy Technology Data Exchange (ETDEWEB)

    Baishali, G., E-mail: baishali@isu.iisc.ernet.in [Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore 560012 (India); Radhakrishna, V.; Koushal, V.; Rakhee, K. [Space Astronomy Group, ISRO Satellite Centre, Bangalore 560017 (India); Rajanna, K. [Department of Instrumentation and Applied Physics, Indian Institute of Science, Bangalore 560012 (India)

    2013-11-21

    The detection efficiency of a GEM based UV sensitive gaseous photomultiplier (GPM) depends on the focusing of electrons from the drift gap to the GEM aperture. We have studied the effect of drift parameters on the efficiency of electron focusing into Thick GEM (THGEM) holes in a GPM with semitransparent UV photoconverter. This study comprises simulation of electron focusing into THGEM holes using GARFIELD for different Ar and Ne based gas mixtures and experimental investigations of the same with P10 gas mixture. -- Highlights: •Effect of drift parameters on detection efficiency of a THGEM based GPM is studied. •Drift parameters studied are drift field, drift gap, gas composition and pressure. •GARFIELD simulation on Electron Transfer Efficiency for various drift parameters. •Experimental studies were carried out for P10 gas at lower multiplication voltage. •Optimization of drift parameters for maximizing the detection efficiency.

  16. Analysis of parental strain DNA fragments existing in GEMs-Fhhh

    Institute of Scientific and Technical Information of China (English)

    HAO Chun-bo; YAN Jun; QU Meng-meng; WANG Dong; CHENG Shu-pei; GU Ji-dong; QIU Wan-fei; WANG Yin-yin

    2003-01-01

    There were 6 target DNA fragments of the three parental strains existing in the cell of GEMs(genetically engineered microorganism strain) Fhhh measured in this research by PCR(polymerase chain reaction). The determination showed that GEMs Fhhh contained all the 6 target DNA fragments, mnp1, mnp2、lip1、lip2, FLO1 and 16S rDNA, and had the molecular genetic stability. Meanwhile the PCR production of each parental strain could only had its target DNA fragments and was different from each other. It may illustrate that the technique of the inter-kingdom protoplast fusion for the construction of GEMs Fhhh through the process of intercellular gene recombination could be used as a reliable bioengineering technique to create the specific functional stain for the pollution control.

  17. A scintillating GEM for 2D-dosimetry in radiation therapy

    CERN Document Server

    Timmer, J; Bom, V; Eijk, C W; Haas, J D; Schippers, J M

    2002-01-01

    The first results of a study on the properties of a gaseous scintillation detector based on a Gas Electron Multiplier (GEM) are reported. The detector is designed for use in position-sensitive dosimetry applications in radiation therapy. A double GEM system, operating in a 90-10% Ar-CO sub 2 gas mixture at a gas amplification factor of approx 3000, emits a sufficient amount of detectable light to perform measurements of approx 1 Gy doses in two dimensions. The light yield does not suffer from quenching processes when particles with high stopping power are detected. This operation mode of GEMs offers the dosimetric advantages of a gas-filled detector and the 2D read-out can be performed with a CCD camera. Compared to the existing dosimeters, this system is relatively simple and no complex multi-electrode read-out is necessary.

  18. Large-size triple GEM detectors for the CMS forward muon upgrade

    CERN Document Server

    Calabria, Cesare

    2014-01-01

    The CMS collaboration considers upgrading the muon forward region which is particularly affected by the high-luminosity conditions at the LHC. The proposal involves Gas Electron Multiplier (GEM) chambers, which are able to handle the extreme particle rates expected in this region along with a high spatial resolution. This allows to combine tracking and triggering capabilities, which will improve the CMS muon High Level Trigger, the muon identification and the track reconstruction. Intense R\\&D has lead to the development of several GEM prototypes and associated detector electronics which were operated in several test beams. Strip cluster parameters, detection efficiency and spatial resolution for charged particles are studied with position and high voltage scans and at different inclination angles. A first GEM station is foreseen to be already installed in LHC Phase-I to operate jointly together with the existing CSC detectors in the forward region. The resulting improved transverse momentum assignment an...

  19. An aging study of triple GEMs in Ar-CO sub 2

    CERN Document Server

    Guirl, L; May, J; Miyamoto, J; Shipsey, I

    2002-01-01

    An aging study was performed using triple GEMs and a print circuit board (PCB) with an intense X-ray radiation source. The GEM chamber consists of three identical GEMs and a large gas gain (6000) was shared by them. The chamber and its gas circulation line was carefully cleaned and constructed with stainless steel materials. The detector was irradiated continuously about 750 h without interruption until a large amount of charge was accumulated. A single-wire counter served as a monitoring device to check the beam and ambient conditions. The quality of the Ar-CO sub 2 gas was checked by gas chromatography and no measurable amount of hydrocarbons were found. 27 mC/mm sup 2 was accumulated with no noticeable degradation and no deposit or discoloration was found in an optical check.

  20. Advances in Trace Element “Fingerprinting” of Gem Corundum, Ruby and Sapphire, Mogok Area, Myanmar

    Directory of Open Access Journals (Sweden)

    F. Lin Sutherland

    2014-12-01

    Full Text Available Mogok gem corundum samples from twelve localities were analyzed for trace element signatures (LA-ICP-MS method and oxygen isotope values (δ18O, by laser fluorination. The study augmented earlier findings on Mogok gem suites that suggested the Mogok tract forms a high vanadium gem corundum area and also identified rare alluvial ruby and sapphire grains characterised by unusually high silicon, calcium and gallium, presence of noticeable boron, tin and niobium and very low iron, titanium and magnesium contents. Oxygen isotope values (δ18O for the ruby and high Si-Ca-Ga corundum (20‰–25‰ and for sapphire (10‰–20‰ indicate typical crustal values, with values >20‰ being typical of carbonate genesis. The high Si-Ca-Ga ruby has high chromium (up to 3.2 wt % Cr and gallium (up to 0. 08 wt % Ga compared to most Mogok ruby (<2 wt % Cr; <0.02 wt % Ga. In trace element ratio plots the Si-Ca-Ga-rich corundum falls into separate fields from the typical Mogok metamorphic fields. The high Ga/Mg ratios (46–521 lie well within the magmatic range (>6, and with other features suggest a potential skarn-like, carbonate-related genesis with a high degree of magmatic fluid input The overall trace element results widen the range of different signatures identified within Mogok gem corundum suites and indicate complex genesis. The expanded geochemical platform, related to a variety of metamorphic, metasomatic and magmatic sources, now provides a wider base for geographic typing of Mogok gem corundum suites. It allows more detailed comparisons with suites from other deposits and will assist identification of Mogok gem corundum sources used in jewelry.

  1. Magnetic activity and orbital period variation of the eclipsing binary KV Gem

    Science.gov (United States)

    Zhang, Liyun; Pi, Qingfeng; Yang, Yuangui; Li, Zhongmu

    2014-02-01

    This paper presents new CCD BVRI light curves of a neglected eclipsing binary KV Gem. Our new light curves were obtained in 2010 and 2011 at the Xinglong station of the National Astronomical Observatories, China. By analyzing all available light minimum times, we derived an update ephemeris and found there existed a cyclic variation overlaying a continuous period decrease. This kind of cyclic variation may probably be attributed to the light-time effect via the presence of an unseen third body or magnetic activity cycle. The long-term period decrease suggests that KV Gem is undergoing a mass transfer from the secondary component to the primary component at a rate of 3.4(0.3)×(10-7 M⊙/year for period decrease and a third body (10.3±0.2 years), and 5.5(0.6)×10-7 M⊙/year for decrease and magnetic cycle (8.8±0.1 years). By analyzing the light curves in 2011, photometric solutions and starspots parameters of the system are obtained using Wilson-Devinney program. Based on the photometric solution in 2011, we still could use the spot model to explain successfully our light curves in 2010 and three published light curves. Comparing the starspot longitudes and factors, KV Gem are variable on a long time scale of about years. For the data of KV Gem, the brightness vary with time around phases 0, 0.25, 0.5, and 0.75, which means that there is a possible photospheric active evolution. More data are needed to monitor to detect stellar cycle of KV Gem. For chromospheric activity of KV Gem, we found strong absorption in the observed Hβ,Hγ, and Ca II H & K spectra, and no obvious emission.

  2. Secondary scintillation yield from GEM and THGEM gaseous electron multipliers for direct dark matter search

    International Nuclear Information System (INIS)

    The search for alternatives to PMTs as photosensors in optical TPCs for rare event detection has significantly increased in the last few years. In particular, in view of the next generation large volume detectors, the use of photosensors with lower natural radioactivity, such as large area APDs or GM-APDs, with the additional possibility of sparse surface coverage, triggered the intense study of secondary scintillation production in micropattern electron multipliers, such as GEMs and THGEMs, as alternatives to the commonly used uniform electric field region between two parallel meshes. The much higher scintillation output obtained from the electron avalanches in such microstructures presents an advantage in those situations. The accurate knowledge of the amount of such scintillation is important for correct detector simulation and optimization. It will also serve as a benchmark for software tools developed and/or under development for the calculation of the amount of such scintillation. The secondary scintillation yield, or electroluminescence yield, in the electron avalanches of GEMs and THGEMs operating in gaseous xenon and argon has been determined for different gas pressures. At 1 bar, THGEMs deliver electroluminescence yields that are more than one order of magnitude higher when compared to those achieved in GEMs and two orders of magnitude when compared to those achieved in a uniform field gap. The THGEM electroluminescence yield presents a faster decrease with pressure when comparing to the GEM electroluminescence yield, reaching similar values to what is achieved in GEMs for xenon pressures of 2.5 bar, but still one order of magnitude higher than that produced in a uniform field gap. Another exception is the GEM operating in argon, which presents an electroluminescence yield similar to that produced in a uniform electric field gap, while the THGEM achieves yields that are more than one order of magnitude higher.

  3. Gemcitabine-loaded albumin nanospheres (GEM-ANPs) inhibit PANC-1 cells in vitro and in vivo

    Science.gov (United States)

    Li, Ji; Di, Yang; Jin, Chen; Fu, Deliang; Yang, Feng; Jiang, Yongjian; Yao, Lie; Hao, Sijie; Wang, Xiaoyi; Subedi, Sabin; Ni, Quanxing

    2013-04-01

    With the development of nanotechnology, special attention has been given to the nanomaterial application in tumor treatment. Here, a modified desolvation-cross-linking method was successfully applied to fabricate gemcitabine-loaded albumin nanospheres (GEM-ANPs), with 110 and 406 nm of mean diameter, respectively. The aim of this study was to assess the drug distribution, side effects, and antitumor activity of GEM-ANPs in vivo. The metabolic viability and flow cytometry analysis revealed that both GEM-ANPs, especially 406-nm GEM-ANPs, could effectively inhibit the metabolism and proliferation and promote the apoptosis of human pancreatic carcinoma (PANC-1) in vitro. Intravenous injection of 406-nm GEM-ANPs exhibited a significant increase of gemcitabine in the pancreas, liver, and spleen of Sprague-Dawley rats ( p < 0.05). Moreover, no signs of toxic side effects analyzed by blood parameter changes were observed after 3 weeks of administration although a high dose (200 mg/kg) of GEM-ANPs were used. Additionally, in PANC-1-induced tumor mice, intravenous injection of 406-nm GEM-ANPs also could effectively reduce the tumor volume by comparison with free gemcitabine. With these findings, albumin nanosphere-loading approach might be efficacious to improve the antitumor activity of gemcitabine, and the efficacy is associated with the size of GEM-ANPs.

  4. 2-dimensional GEM detector with FEE based on the nXYTER ASIC

    International Nuclear Information System (INIS)

    The GEM detector with 2-dimensional readout printed circuit board and an active area 10 × 10 cm2 for detection of diffraction patterns has been developed and constructed. A multichannel front end electronics based on two 128 channel nXYTER chips has been used. The investigations with this detector were made with high rate X-ray sources (6–15 keV). The measurement results of gas gain, spatial resolution and energy resolution are presented. The application of the GEM detector as a potential detector for material science and other diffraction experiments is presented

  5. Discharge probability measurement of a Triple GEM detector irradiated with neutrons

    OpenAIRE

    Croci, G.; Alfonsi, M.; Ropelewski, L.(CERN, Geneva, Switzerland); Tsipolitis, G.; Fanourakis, G.(National Center for Scientific Research “Demokritos”, Athens, Greece); Ntomari, E.; Karakostas, K.

    2013-01-01

    Neutron GEM-based detectors represent a new frontier of diagnostic devices in neutron-linked physics applications such as detectors for fusion experiments (Croci et al., 2012 [1]) and spallation sources (Murtas et al., 2012 [2]). Besides, detectors installed in HEP experiments (like LHC at CERN) are dip in a high flux neutron field. For example, the TOTEM T2 GEM telescope (Bagliesi et al., 2010 [3]) at LHC is currently installed very close to the beam pipe where a high intensity (>104ncm-2s-1...

  6. Gaseous Elemental Mercury (GEM) Emissions from Snow Surfaces in Northern New York

    OpenAIRE

    Maxwell, J. Alexander; Holsen, Thomas M.; Mondal, Sumona

    2013-01-01

    Snow surface-to-air exchange of gaseous elemental mercury (GEM) was measured using a modified Teflon fluorinated ethylene propylene (FEP) dynamic flux chamber (DFC) in a remote, open site in Potsdam, New York. Sampling was conducted during the winter months of 2011. The inlet and outlet of the DFC were coupled with a Tekran Model 2537A mercury (Hg) vapor analyzer using a Tekran Model 1110 two port synchronized sampler. The surface GEM flux ranged from −4.47 ng m−2 hr−1 to 9.89 ng m−2 hr−1. Fo...

  7. Metadata for selecting or submitting generic seismic vulnerability functions via GEM's vulnerability database

    Science.gov (United States)

    Jaiswal, Kishor

    2013-01-01

    This memo lays out a procedure for the GEM software to offer an available vulnerability function for any acceptable set of attributes that the user specifies for a particular building category. The memo also provides general guidelines on how to submit the vulnerability or fragility functions to the GEM vulnerability repository, stipulating which attributes modelers must provide so that their vulnerability or fragility functions can be queried appropriately by the vulnerability database. An important objective is to provide users guidance on limitations and applicability by providing the associated modeling assumptions and applicability of each vulnerability or fragility function.

  8. Quality assurance of GEM foils in the framework of the TPC upgrade in the ALICE experiment

    CERN Document Server

    Ozcelik, Melih Arslan

    2016-01-01

    In the framework of the TPC upgrade of the ALICE Experiment, new readout chambers will be installed during the LHC long shutdown 2, which is scheduled to start in July 2018. The current MWPCs (Multi Wire Proportional Chambers) will be replaced by readout chambers consisting of GEM (Gas Electron Multipliers) foils in order to meet the increasing readout rate requirements. QA (Quality Assurance) tests on the GEMs are performed to classify the foils. In this report we present the work done during the CERN Summer Student Programme 2016.

  9. Optics in the Great Exploration in Math and Science (GEMS) program: a summary of effective pedagogical approaches

    Science.gov (United States)

    Pompea, Stephen M.; Gek, Tan K.

    2002-05-01

    This paper examines how optics is treated in instructional materials developed for the Great Explorations in Math and Science (GEMS) Program at the Lawrence Hall of Science, University of California, Berkeley. The GEMS program is a prominent resource for teachers in the United States and in many other countries. It represents a widely acknowledged, innovative approach to science and mathematics education. GEMS teacher's guides and handbooks offer a wide range of supplementary learning experiences for preschool through 8th grade (about age 13). Two guides already developed (Color Analyzers and More than Magnifiers) and one under development (working title: Invisible Universe) have a strong emphasis on fundamentals of optics. The organization and approaches of the guides will be described, with particular emphasis on the pedagogical approach represented. GEMS activities engage students in direct experience and experimentation in order to introduce essential, standards- based principles and concepts. Overwhelming educational evidence that students learn best by doing is the basis for the GEMS approach.

  10. Divergent Mechanistic Routes for the Formation of gem-Dimethyl Groups in the Biosynthesis of Complex Polyketides

    Energy Technology Data Exchange (ETDEWEB)

    Poust, S; Phelan, RM; Deng, K; Katz, L; Petzold, CJ; Keasling, JD

    2015-01-07

    The gem-dimethyl groups in polyketide-derived natural products add steric bulk and, accordingly, lend increased stability to medicinal compounds, however, our ability to rationally incorporate this functional group in modified natural products is limited. In order to characterize the mechanism of gem-dimethyl group formation, with a goal toward engineering of novel compounds containing this moiety, the gem-dimethyl group producing polyketide synthase (PKS) modules of yersiniabactin and epothilone were characterized using mass spectrometry. The work demonstrated, contrary to the canonical understanding of reaction order in PKSs, that methylation can precede condensation in gem-dimethyl group producing PKS modules. Experiments showed that both PKSs are able to use dimethylmalonyl acyl carrier protein (ACP) as an extender unit. Interestingly, for epothilone module8, use of dimethylmalonyl-ACP appeared to be the sole route to form a gem-dimethylated product, while the yersiniabactin PKS could methylate before or after ketosynthase condensation.

  11. MIT gets good marks for fighting gender discrimination

    Science.gov (United States)

    Gwynne, Peter

    2011-05-01

    The Massachusetts Institute of Technology (MIT) has made "significant progress" in increasing the number of female faculty members, with their numbers in science and engineering almost doubling over the last decade.

  12. Nichterkennen von Vorhofflimmern bei Patienten mit kardialer Resynchronisationstherapie

    Directory of Open Access Journals (Sweden)

    Strohmer B

    2005-01-01

    Full Text Available Obwohl eine Intoleranz der kardialen Resynchronisationstherapie (CRT unüblich ist, sollten entsprechende Symptome auf ihre Ursache hin genau abgeklärt werden. Atriale Tachyarrhythmien (AT werden bei Patienten mit chronischer Herzinsuffizienz relativ häufig beobachtet. Dieser Bericht beschreibt ein rhythmologisches Problem, welches oft unerkannt bleibt und in unserem CRTKollektiv bei knapp 8 % der Patienten aufgetreten ist. Paroxysmales Vorhofflattern wurde durch den CRT-Schrittmacher nicht erkannt, da jede zweite Flatterwelle exakt mit der atrialen Ausblendzeit (PVAB = postventrikuläres atriales Blanking zusammenfiel. Dies führte zu einem Versagen der Mode-Switch-Funktion durch Nichterkennung von stabilem Vorhofflattern, welches mit sehr stabiler Zykluslänge auftrat. Dieses sog. "2:1-lock-in"-Phänomen resultierte in rascher und anhaltender biventrikulärer Stimulation, welche sich bei den betroffenen Patienten klinisch als unangenehmes Herzklopfen mit zunehmender Atemnot bemerkbar machte.

  13. Behandlung des chronischen Tinnitus mit repetitiver transkranieller Magnetstimulation

    OpenAIRE

    Kleinjung, T

    2012-01-01

    Tinnitus ist eine Funktionsstörung des Hörsystems, die von verschiedenen Strukturen und Ebenen ausgehen kann. Tinnitus geht mit neuroplastischen Veränderungen im zentralen auditorischen System einher. Existenz eines „Tinnitus-Netzwerkes“.

  14. The GEM code. A simulation program for the evaporation and the fission process of an excited nucleus

    International Nuclear Information System (INIS)

    The GEM code is a simulation program which describes the de-excitation process of an excited nucleus, which is based on the Generalized Evaporation Model and the Atchison fission model. It has been shown that the combination of the Bertini intranuclear cascade model and GEM accurately predicts the cross sections of light fragments, such as Be produced from the proton-induced reactions. It has also been shown that the use of the reevaluated parameters in the Atchison model improves predictions of cross sections of fission fragments produced from the proton-induced reaction on Au. In this report, we present details and the usage of the GEM code. Furthermore, the results of benchmark calculations are shown by using the combination of the Bertini intranuclear cascade model and the GEM code (INC/GEM). Neutron spectra and isotope production cross sections from the reactions on various targets irradiated by protons are calculated with INC/GEM. Those results are compared with experimental data as well as the calculation results with LAHET. INC/GEM reproduces the experiments of double differential neutron emissions from the reaction on Al and Pb. The isotopic distributions for He, Li, and Be produced from the reaction on Ag are in good agreement with experimental data within 50%, although INC/GEM underestimates those of heavier nuclei than O. It is also shown that the predictions with INC/GEM for isotope production of light fragments, such as Li and Be, are better than those calculation with LAHET, particularly for heavy target. INC/GEM also gives better estimates of the cross sections of fission products than LAHET. (author)

  15. The GEM code. A simulation program for the evaporation and the fission process of an excited nucleus

    Energy Technology Data Exchange (ETDEWEB)

    Furihata, Shiori [Mitsubishi Research Institute Inc., Tokyo (Japan); Niita, Koji [Research Organization for Information Science and Technology, Tokai, Ibaraki (Japan); Meigo, Shin-ichiro; Ikeda, Yujiro; Maekawa, Fujio [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment

    2001-03-01

    The GEM code is a simulation program which describes the de-excitation process of an excited nucleus, which is based on the Generalized Evaporation Model and the Atchison fission model. It has been shown that the combination of the Bertini intranuclear cascade model and GEM accurately predicts the cross sections of light fragments, such as Be produced from the proton-induced reactions. It has also been shown that the use of the reevaluated parameters in the Atchison model improves predictions of cross sections of fission fragments produced from the proton-induced reaction on Au. In this report, we present details and the usage of the GEM code. Furthermore, the results of benchmark calculations are shown by using the combination of the Bertini intranuclear cascade model and the GEM code (INC/GEM). Neutron spectra and isotope production cross sections from the reactions on various targets irradiated by protons are calculated with INC/GEM. Those results are compared with experimental data as well as the calculation results with LAHET. INC/GEM reproduces the experiments of double differential neutron emissions from the reaction on Al and Pb. The isotopic distributions for He, Li, and Be produced from the reaction on Ag are in good agreement with experimental data within 50%, although INC/GEM underestimates those of heavier nuclei than O. It is also shown that the predictions with INC/GEM for isotope production of light fragments, such as Li and Be, are better than those calculation with LAHET, particularly for heavy target. INC/GEM also gives better estimates of the cross sections of fission products than LAHET. (author)

  16. OpenGeoSys-GEMS: Hybrid parallelization of a reactive transport code with MPI and threads

    Science.gov (United States)

    Kosakowski, G.; Kulik, D. A.; Shao, H.

    2012-04-01

    OpenGeoSys-GEMS is a generic purpose reactive transport code based on the operator splitting approach. The code couples the Finite-Element groundwater flow and multi-species transport modules of the OpenGeoSys (OGS) project (http://www.ufz.de/index.php?en=18345) with the GEM-Selektor research package to model thermodynamic equilibrium of aquatic (geo)chemical systems utilizing the Gibbs Energy Minimization approach (http://gems.web.psi.ch/). The combination of OGS and the GEM-Selektor kernel (GEMS3K) is highly flexible due to the object-oriented modular code structures and the well defined (memory based) data exchange modules. Like other reactive transport codes, the practical applicability of OGS-GEMS is often hampered by the long calculation time and large memory requirements. • For realistic geochemical systems which might include dozens of mineral phases and several (non-ideal) solid solutions the time needed to solve the chemical system with GEMS3K may increase exceptionally. • The codes are coupled in a sequential non-iterative loop. In order to keep the accuracy, the time step size is restricted. In combination with a fine spatial discretization the time step size may become very small which increases calculation times drastically even for small 1D problems. • The current version of OGS is not optimized for memory use and the MPI version of OGS does not distribute data between nodes. Even for moderately small 2D problems the number of MPI processes that fit into memory of up-to-date workstations or HPC hardware is limited. One strategy to overcome the above mentioned restrictions of OGS-GEMS is to parallelize the coupled code. For OGS a parallelized version already exists. It is based on a domain decomposition method implemented with MPI and provides a parallel solver for fluid and mass transport processes. In the coupled code, after solving fluid flow and solute transport, geochemical calculations are done in form of a central loop over all finite

  17. Lung Clearance Index bei erwachsenen Patienten mit Mukoviszidose

    OpenAIRE

    Rückel, Helena Sophie

    2011-01-01

    Die Spirometrie mit Bestimmung des forcierten exspiratorischen Volumens in einer Sekunde gilt derzeit als Gold-Standard bei der Beurteilung der Lungenfunktion von Patienten mit Cystischer Fibrose. Da die spirometrische Untersuchung eine aktive Mitarbeit des Patienten erfordert, kann sie jedoch erst etwa ab dem fünften Lebensjahr durchgeführt werden. Im Gegensatz dazu kann der Lung Clearance Index (LCI), der aus Gasdilutionsuntersuchungen abgeleitet wird, in jedem Alter, d.h. auch im Säugl...

  18. Optische Detektion der magnetischen Resonanz mit modengekoppelten Femtosekunden-Pulsen

    OpenAIRE

    Schmidt, Volker

    2000-01-01

    Die vorliegende Arbeit beschäftigt sich mit dem Aufbau eines neuartigen Spektrometers zur Elektronen-Paramagnetischen Resonanz. Die konventionelle magnetische Resonanz wurde hierbei um eine optisch gepulste Detektion, mittels Titan-Saphir-Femtosekunden-Pulslaser erweitert. Als Proben wurden mit diesem neuen Spektrometer Rubin (gepulste ODEPR in Transmission), bzw. ein Fe/V-Multilayer (gepulste ODFMR in Reflektion) untersucht. Die Wechselwirkung zwischen optischer Welle und Magnetisierung...

  19. Biotransformation von 11-Desoxycortisol mit Schizosaccharomyces pombe und Aspergillus nidulans

    OpenAIRE

    Appel, Daniel

    2005-01-01

    In diesem Projekt, welches in Kooperation mit dem Institut für Biochemie der Universität des Saarlandes und der Schering AG Bergkamen durchgeführt wurde, sollte mit Hilfe von rekombinanten Spalthefestämmen, welche die humane Monooxygenase P450 CYP11B1 exprimieren, eine nachhaltigere Bio-Produktion von Hydrocortison entwickelt werden, um das bestehende Verfahren der Hydrocortisonherstellung, mittels des filamentösen Pilz Curvularia lunata zu ersetzen. Um die Optimierung der Hydrocortisonpro...

  20. Makrocyclische Malonatsysteme und deren Reaktionen mit [60]Fulleren

    OpenAIRE

    Brandmüller, Torsten

    2005-01-01

    Im Rahmen dieser Arbeit wurden verschiedenartige makrocyclische Malonate hergestellt und deren Additionsverhalten an [60]Fulleren untersucht. Zunächst wurden sieben verschiedene Makrocyclen mit identischen Alkylketten synthetisiert und charakterisiert, Anschließend wurde die Synthese auf cyclische Malonate mit unterschiedlichen Alkylketten ausgedehnt. Die so erhaltenen makrocyclischen Malonate wurden im Folgenden der Addition an C60 nach BINGEL unterworfen. Hier bilden die symmetrischen Makro...

  1. Clusteranalyse mit gemischtskalierten Merkmalen: SPSS-Makropaket Paare

    OpenAIRE

    Fickel, Norman

    1995-01-01

    Die Statistiksoftware SPSS unterstützt auch in der Version 6 nur Clusteranalysen, wenn alle Merkmale dasselbe Skalenniveau besitzen. Mit dem hier vorgestellten Makropaket Paare kann SPSS auch gemischtskalierte Daten verarbeiten. Der zugrundeliegende Algorithmus abstrahiert dazu durch Abstandsmaße von den unterschiedlichen Skalenniveaus der gegebenen Merkmale. Die Güte der gefundenen Klassifikation läßt sich mit einer Streuungszerlegung sowohl insgesamt als auch merkmalsspezifisch beurteilen

  2. DFB-Laser mit integriert optischer Rückkopplung für die optische Signalverarbeitung

    OpenAIRE

    Brox, Olaf

    2005-01-01

    Im Mittelpunkt dieser Arbeit stehen DFB-Laser mit integriert optischer Rückkopplung und Anwendungen dieser Komponente für die optische Signalverarbeitung. DFB-Laser mit integrierten Rückkoppelsektionen werden hergestellt und experimentell untersucht. Erstmalig erfolgen Untersuchungen an DFB-Lasern mit passiver Rückkopplung (PFL) und DFB-Lasern mit aktiver Rückkopplung (AFL), wobei das Hauptaugenmerk auf der zuverlässigen Erzeugung von Selbstpulsationen mit einer Frequenz von 40 GHz liegt. Sta...

  3. Der Lebenslauf von Menschen mit Asperger Syndrom / High-Functioning Autismus : eine Interviewstudie mit Schwerpunkt auf dem Erwachsenenalter

    OpenAIRE

    Gomolla, Annette

    2002-01-01

    Über den Lebensverlauf und insbesondere das Erwachsenenalter von Menschen mit Asperger Syndrom (AS) / High-Functioning Autismus (HFA) ist bisher wenig bekannt, insbesondere gibt es keine Studien, die die Erfahrungen und Bewertungen der Personen selbst in den Mittelpunkt stellen. Die vorliegende Studie hat sich bemüht, bestehende Informationen und Einschätzungen Dritter über Kindheit, Jugendzeit und Erwachsenenalter mit den subjektiven Sichtweisen dieser Personengruppe zu vergleichen und spezi...

  4. Development and Test of a GEM-Based TEPC System for In-Phantom Dose Measurements

    Energy Technology Data Exchange (ETDEWEB)

    C-K Chris Wang

    2007-03-13

    The objectives of this project include: (1) to construct a minature tissue equivalent proportional counter (TEPC) using a gas-electron-multiplier (GEM) foil, and (2) to conduct neutron and gamma-ray dose measurements with the detector embedded in a phantom

  5. Studies of characteristics of triple GEM detector for the ALICE-TPC upgrade

    International Nuclear Information System (INIS)

    Gas Electron Multiplier (GEM) is a novel gas detector in the field of radiation detection. GEM detectors have tremendous advantages over other types gas detectors like high rate handling capability with high efficiency and very low ion back flow (IBF). These detectors are most suitable for the use in the future experiments in high-energy proton-proton and heavy-ion collisions at the Large Hadron Collider (LHC) at CERN and Facility for Antiproton and Ion Research (FAIR) at GSI. A Large Ion Collider Experiment (ALICE) at the LHC is a dedicated experiment for the study of Quark Gluon Plasma (QGP). In few years, the data taking rate for Pb-Pb collisions will increase by 100 times to 50 KHz. The ALICE Time Projection Chamber (TPC) is the main tracking detector in ALICE. It is planned that by the year 2018, GEM detectors will replace the present readout planes of TPC. The goal of the present study is to characterize the GEM detector to achieve the performance goal of the TPC

  6. Promoting microbiology education through the iGEM synthetic biology competition.

    Science.gov (United States)

    Kelwick, Richard; Bowater, Laura; Yeoman, Kay H; Bowater, Richard P

    2015-08-01

    Synthetic biology has developed rapidly in the 21st century. It covers a range of scientific disciplines that incorporate principles from engineering to take advantage of and improve biological systems, often applied to specific problems. Methods important in this subject area include the systematic design and testing of biological systems and, here, we describe how synthetic biology projects frequently develop microbiology skills and education. Synthetic biology research has huge potential in biotechnology and medicine, which brings important ethical and moral issues to address, offering learning opportunities about the wider impact of microbiological research. Synthetic biology projects have developed into wide-ranging training and educational experiences through iGEM, the International Genetically Engineered Machines competition. Elements of the competition are judged against specific criteria and teams can win medals and prizes across several categories. Collaboration is an important element of iGEM, and all DNA constructs synthesized by iGEM teams are made available to all researchers through the Registry for Standard Biological Parts. An overview of microbiological developments in the iGEM competition is provided. This review is targeted at educators that focus on microbiology and synthetic biology, but will also be of value to undergraduate and postgraduate students with an interest in this exciting subject area.

  7. Validation of neutron texture data on GEM at ISIS using electron backscattered diffraction

    Science.gov (United States)

    Davies, Peter; Kockelmann, Winfried; Wynne, Brad; Eccleston, Roger; Hutchinson, Bevis; Rainforth, W. Mark

    2008-03-01

    The high solid angular coverage of the general materials (GEM) diffractometer at the ISIS pulsed neutron source located at the UK Rutherford Appleton Laboratory offers the capability of obtaining quantitative bulk crystallographic texture data in a 'single shot' within a matter of minutes. This enables the possibility of in situ texture measurements to be made as a function of temperature to monitor and quantify texture changes during phase transformation or microstructure restoration processes like recrystallization. The purpose of this paper is to determine the quality of the texture data produced from GEM in order to define a level of confidence for subsequent texture model validation. This has been achieved by comparing textures of sections of a 200 mm diameter titanium alloy billet using data obtained from GEM with data obtained using electron backscattered diffraction (EBSD). In both cases, the data were obtained at room temperature. EBSD, unlike time-of-flight neutron diffraction analysis, obtains texture data directly from orientation measurements via backscattered Kikuchi patterns in the scanning electron microscope. In all analysed locations, both methods show near-identical textures, with regard to both the general orientation distributions and the levels of intensity of the distributions. This shows that the GEM diffractometer is capable of accurately determining bulk textures in a single shot, thus confirming its suitability for in situ high temperature experiments.

  8. Physics motivations and expected performance of the CMS muon system upgrade with triple-GEM detectors

    CERN Document Server

    Venditti, Rosamaria; Abbrescia, Marcello; Aleksandrov, Andrey B; Benussi, Luigi; Beni, Noemi; Bianco, Stefano; Calabria, Cesare; Caponero, Michele; Hernandez, Alfredo Martin Castaneda; Cavallo, Francesca; Colafranceschi, Stefano; Lentdecker, Gilles De; Oliveira, R; Guiducci, Luigi; Hoepfner, Kerstin; Iaydjiev, P S; Korytov, Andrey; Krutelyov, Slava; Kumar, A; Lee, Jason; Litov, L; Loddo, F; Maggi, M; Marchioro, Alessandro; Mitselmakher, Guenakh; Mohanty, Ajit Kumar; Molnar, J; Naimuddin, Md; Nuzzo, S; Pant, Lalit; Paolucci, Pierluigi; Pavlov, Borislav; Piccolo, Davide; Postema, Hans; Raffaella, Radogna; Ranieri, A; Riccardi, C; Rodozov, Mircho; Safonov, Alexei; Saviano, Giovanna; Sharma, Archana; Tytgat, Michael; Vitulo, Paolo; Colaleo, Anna; Caputo, Claudio; Errico, Filippo; Dildick, Sven; Vai, Ilaria; Magnani, Alice; Verwilligen, Piet; Altieri, Palma; Aspell, Paul; Giacomelli, Paolo; Braibant, Sylvie; Buontempo, S; Kamon, Teruki; Tatarinov, A; Celik, Ali; Gilmore, Jason; Flanagan, Will; Khotilovich, Vadim; Czellar, S; Fenyvesi, A; Jozsef Molnar@Cern Ch, Jozsef; Barria, P; Korntheuer, Michael; Lenzi, T; Maerschalk, T; Verhagen, E; Yang, Yifan; Yonamine, R; Zenoni, F; Merlin, J; Dorney, B; Garcia, A Conde; Dabrowski, M; Marinov, A; Oliveri, E; Baranac, A Puig; Ropelewski, Leszek; Bos, J; Bally, S; Stenis, M Van; Ferry, S; Rodrigues, A; Robertis, G De; Christiansen, J; Hohlmann, M; Bhopatkar, V; Mohapatra, A; Zhang, A; Hauser, J; Tuuva, Tuure; Talvitie, J; Passeggio, G; Cassese, F; Banerjee, S; Majumdar, N; Mukhopadhyay, Supratik; Roychowdhur, S; Salva, S; Zaganidis, N; Cimmino, A; Cauwenbergh, S; Bouhali, O; Akl, M Abi; Sturdy, J; Karchin, P; Gutierrez, A; Hadjiiska, R; Aleksandrov, Aleksandar; Rashevski, G; Rodozov, M; Shopova, M; Sultanov, G; Acosta, D; Barashko, V; Furic, I; Madorsky, A; Korytov, A; Mitselmakher, G; Raffone, G; Radi, A; Assran, Y; Aboamer, O; Ahmad, A; Ahmed, W; Awan, I; Hoorani, H; Muhammad, S; Sharma, R; Geonmo, R; Ryu, M S; Park, I; Jeng, Y C; Choi, M; Golovtsov, V; Volkov, S; Vorobyev, A; Choi, S; Guilloux, F; Philipps, B

    2015-01-01

    For the LHC High Luminosity phase (HL-LHC) the CMS GEM Collaboration is planning to in- stall new large size triple-GEM detectors in the forward region of the muon system (1.5< j h |<2.2) of the CMS detector. The muon reconstruction with triple-GEM chambers information included have been successfully integrated in the official CMS software, allowing physics studies to be carried out. The new sub-detector will be able to cope the extreme particle rates expected in this region along with a high spatial resolution. The resulting benefit in terms of triggering and tracking capabilities has been studied: the expected improvement in the performance of the muon identification and track reconstruction as well as the expected improvement coming from the low- ering of the muon p T trigger tresholds will be presented. The contribution will review the status of the CMS upgrade project with the usage of GEM detector, discussing the trigger, the muon reconstruction performance and the impact on the physics analyses.

  9. Evaluation of the GEM-AQ model in the context of the AQMEII Phase 1 project

    Directory of Open Access Journals (Sweden)

    J. Struzewska

    2015-01-01

    Full Text Available In the scope of the AQMEII Phase 1 project the GEM-AQ model was run over Europe for the year 2006. The modelling domain was defined using a global variable resolution grid with a rotated equator and uniform resolution of 0.2° × 0.2° over the European continent. Spatial distribution and temporal variability of the GEM-AQ model results were analysed for surface ozone and PM10 concentrations. Model results were compared with measurements available in the ENSEMBLE database. Statistical measures were used to evaluate performance of the GEM-AQ model. The mean bias error, the mean absolute gross error and the Pearson correlation coefficient were calculated for the maximum 8 h running average ozone concentrations and daily mean PM10 concentrations. The GEM-AQ model performance was characterised for station types, European climatic regions, and seasons. The best performance for ozone was obtained at suburban stations and the worst performance was obtained for rural stations where the model tends to underestimate. The best results for PM10 were calculated for urban stations, while over most of Europe concentrations at rural sites were too high. Discrepancies between modelled and observed concentrations were discussed in the context of emission data uncertainty as well as the impact of large scale dynamics and circulation of air masses. Presented analyses suggest that interpretation of modelling results is enhanced when regional climate characteristics are ta ken into consideration.

  10. hpGEM -- A software framework for discontinuous Galerkin finite element methods

    NARCIS (Netherlands)

    Pesch, L.; Bell, A.; Sollie, W.E.H.; Ambati, V.R.; Bokhove, O.; Vegt, van der J.J.W.

    2007-01-01

    hpGEM, a novel framework for the implementation of discontinuous Galerkin finite element methods (FEMs), is described. We present data structures and methods that are common for many (discontinuous) FEMs and show how we have implemented the components as an object-oriented framework. This framework

  11. hpGEM -- A software framework for discontinuous Galerkin finite element methods

    NARCIS (Netherlands)

    Pesch, L.; Bell, A.; Sollie, W.E.H.; Ambati, V.R.; Bokhove, O.; Vegt, van der J.J.W.

    2006-01-01

    hpGEM, a novel framework for the implementation of discontinuous Galerkin finite element methods, is described. We present structures and methods that are common for many (discontinuous) finite element methods and show how we have implemented the components as an object-oriented framework. This fra

  12. The design of a DAQ system for a GEM imaging detector based on FET array readout

    International Nuclear Information System (INIS)

    A data acquisition system was designed for a GEM imaging detector, which is readout by a FET switch array and can be used in real-time imaging. By using some advanced technologies, like FPGA and MCU, the designed DAQ system succeeds in multi-channel real-time readout with high-accuracy and high universality. (authors)

  13. Experiential Engineering through iGEM--An Undergraduate Summer Competition in Synthetic Biology

    Science.gov (United States)

    Mitchell, Rudolph; Dori, Yehudit Judy; Kuldell, Natalie H.

    2011-01-01

    Unlike students in other engineering disciplines, undergraduates in biological engineering typically have limited opportunity to develop design competencies, and even fewer chances to implement their designed projects. The international Genetically Engineered Machines (iGEM) competition is a student Synthetic Biology competition that, in 2009,…

  14. Application of CMOS charge-sensitive preamplifier in triple-GEM detector

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Among the various micro-pattern gas detectors (MPGD) that are available, the gas electron multiplier (GEM) detector is an attractive gas detector that has been used in particle physics experiments. However the GEM detector usually needs thousands of preamplifier units for its large number of micro-pattern readout strips or pads,which leads to considerable difficulties and complexities for front end electronics (FEE). Nowadays, by making use of complementary metal-oxide semiconductor (CMOS)-based application specific integrated circuit (ASIC), it is feasible to integrate hundreds of preamplifier units and other signal process circuits in a small-sized chip, which can be bound to the readout strips or pads of a micro-pattern particle detector (MPPD). Therefore, CMOS ASIC may provide an ideal solution to the readout problem of MPPD. In this article, a triple GEM detector is constructed and one of its readout strips is connected to a CMOS charge-sensitive preamplifier chip. The chip was exposed to an 55Fe source of 5.9 keV X-ray, and the amplitude spectrum of the chip was tested, and it was found that the energy resolution was approximately 27%, which indicates that the chip can be used in triple GEM detectors.

  15. The gem collection of the Rijksmuseum van Geologie en Mineralogie of Leiden The Peridots

    NARCIS (Netherlands)

    Zwaan, P.C.

    1957-01-01

    The peridots in the gem collection of our Museum were acquired a long time ago (part of them were from the collection of King William I of the Netherlands). We should be sceptical about data on the origin of this material. Firstly we do not generally know whether the stones were bought or received a

  16. LHCb: A fast triple-GEM detector for high-rate charged-particle triggering

    CERN Multimedia

    2001-01-01

    - GEM: Principle of Operation - Time Performances - Detector Prototypes and Test Setup - Gas Mixtures - Fields Optimisation - Vgem Optimisation Ar/CO2 (70/30) - Vgem Optimisation Ar/CO2/CF4 (60/20/20) - Time Distributions - Future Tests and Developments

  17. A geopotential model from satellite tracking, altimeter, and surface gravity data: GEM-T3

    Science.gov (United States)

    Lerch, F. J.; Nerem, R. S.; Putney, B. H.; Felsentreger, T. L.; Sanchez, B. V.; Marshall, J. A.; Klosko, S. M.; Patel, G. B.; Williamson, R. G.; Chinn, D. S.

    1994-01-01

    An improved model of Earth's gravitational field, Goddard Earth Model T-3 (GEM-T3), has been developed from a combination of satellite tracking, satellite altimeter, and surface gravimetric data. GEM-T3 provides a significant improvement in the modeling of the gravity field at half wavelengths of 400 km and longer. This model, complete to degree and order 50, yields more accurate satellite orbits and an improved geoid representation than previous Goddard Earth Models. GEM-T3 uses altimeter data from GEOS 3 (1975-1976), Seasat (1978) and Geosat (1986-1987). Tracking information used in the solution includes more than 1300 arcs of data encompassing 31 different satellites. The recovery of the long-wavelength components of the solution relies mostly on highly precise satellite laser ranging (SLR) data, but also includes Tracking Network (TRANET) Doppler, optical, and satellite-to-satellite tracking acquired between the ATS 6 and GEOS 3 satellites. The main advances over GEM-T2 (beyond the inclusion of altimeter and surface gravity information which is essential for the resolution of the shorter wavelength geoid) are some improved tracking data analysis approaches and additional SLR data. Although the use of altimeter data has greatly enhanced the modeling of the ocean geoid between 65 deg N and 60 deg S latitudes in GEM-T3, the lack of accurate detailed surface gravimetry leaves poor geoid resolution over many continental regions of great tectonic interest (e.g., Himalayas, Andes). Estimates of polar motion, tracking station coordinates, and long-wavelength ocean tidal terms were also made (accounting for 6330 parameters). GEM-T3 has undergone error calibration using a technique based on subset solutions to produce reliable error estimates. The calibration is based on the condition that the expected mean square deviation of a subset gravity solution from the full set values is predicted by the solutions' error covariances. Data weights are iteratively adjusted until

  18. Open source large-scale high-resolution environmental modelling with GEMS

    Science.gov (United States)

    Baarsma, Rein; Alberti, Koko; Marra, Wouter; Karssenberg, Derek

    2016-04-01

    Many environmental, topographic and climate data sets are freely available at a global scale, creating the opportunities to run environmental models for every location on Earth. Collection of the data necessary to do this and the consequent conversion into a useful format is very demanding however, not to mention the computational demand of a model itself. We developed GEMS (Global Environmental Modelling System), an online application to run environmental models on various scales directly in your browser and share the results with other researchers. GEMS is open-source and uses open-source platforms including Flask, Leaflet, GDAL, MapServer and the PCRaster-Python modelling framework to process spatio-temporal models in real time. With GEMS, users can write, run, and visualize the results of dynamic PCRaster-Python models in a browser. GEMS uses freely available global data to feed the models, and automatically converts the data to the relevant model extent and data format. Currently available data includes the SRTM elevation model, a selection of monthly vegetation data from MODIS, land use classifications from GlobCover, historical climate data from WorldClim, HWSD soil information from WorldGrids, population density from SEDAC and near real-time weather forecasts, most with a ±100m resolution. Furthermore, users can add other or their own datasets using a web coverage service or a custom data provider script. With easy access to a wide range of base datasets and without the data preparation that is usually necessary to run environmental models, building and running a model becomes a matter hours. Furthermore, it is easy to share the resulting maps, timeseries data or model scenarios with other researchers through a web mapping service (WMS). GEMS can be used to provide open access to model results. Additionally, environmental models in GEMS can be employed by users with no extensive experience with writing code, which is for example valuable for using models

  19. The GTPase Gem and its partner Kif9 are required for chromosome alignment, spindle length control, and mitotic progression.

    Science.gov (United States)

    Andrieu, Guillaume; Quaranta, Muriel; Leprince, Corinne; Hatzoglou, Anastassia

    2012-12-01

    Within the Ras superfamily, Gem is a small GTP-binding protein that plays a role in regulating Ca(2+) channels and cytoskeletal remodeling in interphase cells. Here, we report for the first time that Gem is a spindle-associated protein and is required for proper mitotic progression. Functionally, loss of Gem leads to misaligned chromosomes and prometaphase delay. On the basis of different experimental approaches, we demonstrate that loss of Gem by RNA interference induces spindle elongation, while its enforced expression results in spindle shortening. The spindle length phenotype is generated through deregulation of spindle dynamics on Gem depletion and requires the expression of its downstream effector, the kinesin Kif9. Loss of Kif9 induces spindle abnormalities similar to those observed when Gem expression is repressed by siRNA. We further identify Kif9 as a new regulator of spindle dynamics. Kif9 depletion increases the steady-state levels of spindle α-tubulin by increasing the rate of microtubule polymerization. Overall, this study demonstrates a novel mechanism by which Gem contributes to the mitotic progression by maintaining correct spindle length through the kinesin Kif9.

  20. Demenz und Depression bei Patienten mit idiopathischem Parkinson-Syndrom

    Directory of Open Access Journals (Sweden)

    Herting B

    2007-01-01

    Full Text Available Das idiopathische Parkinson-Syndrom (IPS ist eine progressive neurodegenerative Erkrankung mit motorischen und nicht-motorischen Symptomen. Bei Patienten mit IPS sind kognitive Defizite und Demenzen mit einer Prävalenz von 20–40 % nachgewiesen worden. Risikofaktoren für das Auftreten einer Parkinson-Demenz (PDe sind hohes Alter bei Krankheitsbeginn, schwere und/oder beidseitige motorische Symptomatik, Verwirrtheitszustände unter Levodopa-Medikation, aber auch Demenzerkrankungen in der Familie und niedriges Bildungsniveau. Patienten mit PDe weisen eine erhöhte Morbidität und Mortalität im Vergleich zu Patienten mit IPS ohne Demenz und der altersgleichen Normalbevölkerung auf, die unabhängig von der Schwere der motorischen Einbußen zweifach erhöht ist. Die Depression ist das häufigste psychiatrische Symptom beim IPS (die Angaben zur Prävalenz schwanken zwischen 4 % und 70 % und beeinflußt neben den Aktivitäten des täglichen Lebens wesentlich die Lebensqualität der Betroffenen. Darin liegt auch die Herausforderung, kognitive und affektive Symptome effizient zu behandeln.

  1. The micro turbine: the MIT example; La micro turbine: l'exemple du MIT

    Energy Technology Data Exchange (ETDEWEB)

    Ribaud, Y. [Office National d' Etudes et de Recherches Aerospatiales (ONERA-DEFA), 92 - Chatillon (France)

    2001-10-01

    The micro turbine study began a few years ago at the MIT, with the participation of specialists from different fields. The purpose is the development of a MEMS (micro electro mechanical systems) based, 1 cm in diameter, micro gas turbine. Potential applications are devoted to micro drone propulsion, electric power generation for portable power sources in order to replace heavy Lithium batteries, satellite motorization, the surface distributed power for boundary suction on plane wings. The manufacturing constraints at such small scales lead to 2-D extruded shapes. The physical constraints stem from viscous effects and from limitations given by 2-D geometry. The time scales are generally shorter than for conventional machines. Otherwise the material properties are better at such length scales. Transposition from conventional turbomachinery laws is no more applicable and new design methods must be established. The present paper highlights the project progress and the technology breakthroughs. (author)

  2. The Growth Entrapment Model (GEM): New Insights from Molecular-Scale Simulations of Ti in Quartz

    Science.gov (United States)

    Watson, E. B.; Lanzillo, N. A.; Nayak, S. K.

    2011-12-01

    The growth entrapment model (GEM) put forth by Watson and Liang (Am. Min. 80, 1170-1187) and Watson (GCA 68, 1473-1488) offers a mechanism by which crystals can acquire non-equilibrium chemical or isotopic properties during growth from a uniform fluid medium. The GEM is based on the premise that the equilibrium properties of the near-surface region of a crystal differ from those of the bulk, much as the properties of nanocrystals differ from those of larger crystals of the same phase. In the GEM model, "capture" of the near-surface composition within a growing crystal-creating a non-equilibrium condition-depends upon the outcome of the competition between growth (which buries near-surface atoms) and diffusion (which attempts to restore equilibrium). In any application of the GEM model, the most uncertain input parameters are the near-surface diffusivity (D) and the equilibrium partition coefficient (F) between the near-surface region and the bulk lattice. Experimental measurement of these quantities is elusive because the relevant length scales are small (1-5 nm). However, molecular-scale simulations hold some promise for deducing relative values, as we illustrate here using Ti uptake in quartz as an example. We undertook ab initio molecular dynamics simulations based on a supercell approach to show that the binding energy of Ti^{4+} in quartz is a function of depth in the crystal within a few nanometers of the surface, confirming that F in the GEM model must differ from unity. We also show, using the meta-dynamics method to compute the unbiased diffusion path and corresponding energy barrier, that the activation energy for Ti^{4+} diffusion in the near-surface (2-3 nm deep) is substantially lower than that pertaining to the "deep" lattice diffusivity that is typically measured in diffusion experiments (which we also reproduced computationally). These findings substantiate the underlying phenomena upon which the GEM model is based, in addition to providing

  3. Islam, Migration und Integration: Konflikte jugendlicher Migranten mit islamischem Hintergrund

    Directory of Open Access Journals (Sweden)

    Ilhan Kizilhan

    2008-04-01

    Full Text Available Der Islam mit seinen verschiedenen Verhaltensweisen und Verboten spielt direkt oder indirekt immer noch eine wichtige Rolle im alltäglichen Leben vieler Migranten. Religiöse Vorschriften zeichnen sich dadurch aus, dass ihrer Achtung nicht juristisch, sondern durch sozialen Druck Nachdruck verliehen wird (Verwandtschaft, religiöse Lehrer, islamische Gemeinde, religiöse Vereine etc. und dass ihre Missachtung mit Folgen in Form von Ausgrenzung, Missachtung und Diskriminierung einhergeht. Die kulturellen Vorstellungen der ersten Generation unterscheiden sich auf Grund der unterschiedlichen Biografien von denen der zweiten und dritten durch den Grad der Verwurzelung in der kulturellen Identität und der Verbundenheit mit traditionellen Wertvorstellungen. Fehlende Integrationskonzepte, Ausgrenzung im Migrationsland auf der einen und weltweite staatliche und halbstaatliche Konflikte im Namen des Islams bis hin zum Terrorismus auf der anderen Seite haben einen erheblichen Einfluss auf den Integrationsgrad von jugendlichen Migranten im Aufnahmeland.

  4. Professionell entwickeln mit Java EE 7 das umfassende Handbuch

    CERN Document Server

    Salvanos, Alexander

    2014-01-01

    Ein praxisorientiertes Lehrbuch zur JEE 7 und zugleich ein Standardwerk, das Sie auf Ihrem Weg zum Enterprise-Entwickler begleitet. Inklusive Best Practices für leichtgewichtige Enterprise Applications, Standards zu servicebasierten Anwendungen, Persistence API, Dependency Injection, HTML5 und Performance-Tuning. Aus dem Inhalt: Grundlagen und Installation Software-Architektur mit Java EE Webanwendungen mit HTML5 und CSS3 Java Standard Tag Library Asynchrone Servlets und Non-blocking I/O Datenbanken anbinden mit der JDBC API Java Server Faces Datenbank-Organisation Java Persistence API Objektrelationales Mapping Transaktionssicherheit Performance-Tuning Internationalisierung Enterprise Java Beans WebSockets PrimeFaces Deployment Galileo Press heißt von jetzt an Rheinwerk Verlag.

  5. Large Size GEM for Super Bigbite Spectrometer (SBS) Polarimeter for Hall A 12 GeV program at JLab

    CERN Document Server

    Gnanvo, Kondo; Nelyubin, Vladimir; Saenboonruang, Kiadtisak; Sacher, Seth; Wojtsekhowski, Bogdan

    2014-01-01

    We report on the R&D effort in the design and construction of a large size GEM chamber for the Proton Polarimeter of the Super Bigbite Spectrometer (SBS) in Hall A at Thomas Jefferson National Laboratory (JLab). The SBS Polarimeter trackers consist of two sets of four large chambers of size 200 cm x 60 cm. Each chamber is a vertical stack of four GEM modules with an active area of 60 cm x 50 cm. We have built and tested several GEM modules and we describe in this paper the design and construction of the final GEM as well as the preliminary results on performances from tests carried out in our detector lab and with test beams at Fermilab.

  6. Design and implementation of the infrastructure of HadGEM3: the next-generation Met Office climate modelling system

    Directory of Open Access Journals (Sweden)

    H. T. Hewitt

    2010-10-01

    Full Text Available This paper describes the development of a technically robust climate modelling system, HadGEM3, which couples the Met Office Unified Model atmosphere component, the NEMO ocean model and the Los Alamos sea ice model (CICE using the OASIS coupler. Details of the coupling and technical solutions are documented in the paper in addition to a description of the configurations of the individual submodels. The paper demonstrates that the implementation of the model has resulted in accurate conservation of heat and freshwater across the model components. The model performance in early versions of this climate model is briefly described to demonstrate that the results are scientifically credible. HadGEM3 is the basis for a number of modelling efforts outside of the Met Office, both within the UK and internationally. This documentation of the HadGEM3 system provides a detailed reference for developers of HadGEM3-based climate configurations.

  7. Progress on the realization of a new GEM based neutron diagnostic concept for high flux neutron beams

    Science.gov (United States)

    Croci, G.; Rebai, M.; Cazzaniga, C.; Palma, M. Dalla; Grosso, G.; Muraro, A.; Murtas, F.; Claps, G.; Pasqualotto, R.; Cippo, E. Perelli; Tardocchi, M.; Tollin, M.; Cavenago, M.; Gorini, G.

    2014-08-01

    Fusion reactors will need high flux neutron detectors to diagnose the deuterium-deuterium and deuterium-tritium. A candidate detection technique is the Gas Electron Multiplier (GEM). New GEM based detectors are being developed for application to a neutral deuterium beam test facility. The proposed detection system is called Close-contact Neutron Emission Surface Mapping (CNESM). The diagnostic aims at providing the map of the neutron emission due to interaction of the deuterium beam with the deuterons implanted in the beam dump surface. This is done by placing a detector in close contact, right behind the dump. CNESM uses nGEM detectors, i.e. GEM detectors equipped with a cathode that also serves as neutron-proton converter foil. After the realization and test of several small area prototypes, a full size prototype has been realized and tested with laboratory sources. Test on neutron beams are foreseen for the next months.

  8. Wege zu einem nachhaltigen Umgang mit Süßwasser

    OpenAIRE

    Wissenschaftlicher Beirat Globale Umweltveränderungen

    2009-01-01

    Der Umgang mit Wasser – seine Erschließung, Verteilung, Nutzung, Reinhaltung und Abwehr – hat die Geschichte der menschlichen Zivilisation nachhaltig geprägt. Der Umgang mit Wasser ist aber auch eine der vorrangigen Aufgaben der Gegenwart. Heute leben rund 2 Mrd. Menschen ohne Zugang zu sauberem Trink- und Sanitärwasser (Gleick, 1993), weltweit werden nur 5% der Abwässer gereinigt. Infolgedessen leidet jeder zweite Mensch in den Entwicklungsländern an einer wasserbedingten Krankheit; 5 Mio. M...

  9. Mikrostrukturierte segmentierte Paul-Falle mit einstellbarem Magnetfeldgradienten

    OpenAIRE

    Kaufmann, Delia

    2012-01-01

    Lasergekühlte Ionenketten in mikrostrukturierten Paul-Fallen (Mikrofallen) bieten ein großes Potential für Anwendungen in den Quanteninformationswissenschaften. Sie können in einer dekohärenzarmen Umgebung präpariert und manipuliert, und ihre Zustände mit einer Effizienz von fast 100% detektiert werden. Mit zusätzlichen Magnetfeldgradienten ist es möglich, die Ionen im Frequenzraum zu adressieren und zu koppeln (MAGIC-Methode - MAgnetic Gradient Induced Coupling). In dieser Arbeit wurde ei...

  10. Enantioselektive katalytische Hydrierung mit polymerfixiertem Katalysator auf einer Kieselgurmatrix

    OpenAIRE

    Jaser, Karl

    2004-01-01

    Diese Arbeit beschäftigt sich mit der Fixierung des enantioselektiven Rhodium-Pyrphos-Katalysators auf einer inerten Kieselgurmatrix. Dabei wird als Polymer Glycerin-tris[polypropylenglycol-amingestoppt]-ether verwendet, das mit 1,3,5-Benzoltricarbonsäure-trichlorid oder 1,6-Diisocyanato-hexan vernetzt wird. Die Hydrierdauer einer bestimmten Menge Acetamidozimtsäure, der Umsatz und der ee-Wert, die im Batch-Betrieb ermittelt wurden, lassen einen Rückschluss auf die Menge des reaktiven Rhodium...

  11. Time analysis of the light pulses on gaseous active scintillators using GEMs with He/CF4

    OpenAIRE

    Margato, L. M. S.; Fraga, F. A. F.; Fetal, S. T. G.; Fraga, M. M. F. R.; Marques, R. Ferreira; Policarpo, A. J. P. L.; Guerard, B.; Manzin, G.

    2003-01-01

    The time structure of light pulses from GEM detectors operated in scintillation mode with He/CF4 mixtures, previously used with integrating readout devices for neutron detection, has been investigated. A system using photomultipliers (PMs) and charge preamplifiers coupled to a fast digitizer has been used to measure simultaneously both the charge and light signals of the avalanches and the dependence of these signals on the operating conditions of the GEM, such as gain, transfer yield and col...

  12. Atmospheric gaseous elemental mercury (GEM) concentrations and mercury depositions at a high-altitude mountain peak in south China

    OpenAIRE

    X. W. Fu; Feng, X.; Dong, Z. Q.; R. S. Yin; Wang, J. X.; Yang, Z. R.; Zhang, H.

    2010-01-01

    China is regarded as the largest contributor of mercury (Hg) to the global atmospheric Hg budget. However, concentration levels and depositions of atmospheric Hg in China are poorly known. Continuous measurements of atmospheric gaseous elemental mercury (GEM) were carried out from May 2008 to May 2009 at the summit of Mt. Leigong in south China. Simultaneously, deposition fluxes of THg and MeHg in precipitation, throughfall and litterfall were also studied. Atmospheric GEM concentrations aver...

  13. Application of GemDialogue and GemSet Colour System in Colour Description and Grading of Coloured Gemstones%GemDialogue和GemSet颜色系统在有色宝石颜色描述和分级中的应用

    Institute of Scientific and Technical Information of China (English)

    李立平; 陈华; 罗劬侃

    2005-01-01

    国际贸易中有色宝石的报价主要是按其总品质级别和克拉质量给出的.目前,国际上较为广泛采用的有色宝石的分级体系主要有美国宝石学院和美国宝石协会的两个体系.在有色宝石总品质中起决定作用的是颜色,对宝石颜色的描述和分级分别采用的是GIA的GemSet和Howard Rubin的GemDialogue颜色系统.主要介绍这两个系统的特点以及它们在有色宝石颜色描述和分级中的应用方法及应注意的问题.

  14. Optical readout of a triple-GEM detector by means of a CMOS sensor

    Science.gov (United States)

    Marafini, M.; Patera, V.; Pinci, D.; Sarti, A.; Sciubba, A.; Spiriti, E.

    2016-07-01

    In last years, the development of optical sensors has produced objects able to provide very interesting performance. Large granularity is offered along with a very high sensitivity. CMOS sensors with millions of pixels able to detect as few as two or three photons per pixel are commercially available and can be used to read-out the optical signals provided by tracking particle detectors. In this work the results obtained by optically reading-out a triple-GEM detector by a commercial CMOS sensor will be presented. A standard detector was assembled with a transparent window below the third GEM allowing the light to get out. The detector is supplied with an Ar/CF4 based gas mixture producing 650 nm wavelength photons matching the maximum quantum efficiency of the sensor.

  15. First Tests of MICROMEGAS and GEM-Like Detectors Made of a Resistive Mesh

    CERN Document Server

    Oliveira, R; Peskov, V; Pietropaolo, F

    2010-01-01

    We describe here various detector designs: GEM-type, MICROMEGAS-type, as well as cascaded detectors made of a resistive mesh manufactured from a resistive Kapton foil, (20 mu m thick, surface resistivity a few M Omega/cm(2)) by a laser drilling technique. As in any other micro-pattern detector, the maximum achievable gas gain of these detectors is restricted by the Raether limit; however, the resistive mesh makes them and the front end electronics fully spark protected. This approach may function as an alternative/or complementary component of the ongoing efforts in developing MICROMEGAS and GEMs with resistive anode readout plates and can be especially beneficial in micro-pattern detectors combined with a micro-pixel-type integrated front end electronics.

  16. Dependence of Limited Growth Rate of High-Quality Gem Diamond on Growth Conditions

    Institute of Scientific and Technical Information of China (English)

    TIAN Yu; MA Hong-An; LI Shang-Sheng; XIAO Hong-Yu; ZHANG Ya-Fei; HUANG Guo-Feng; MA Li-Qiu; JIA Xiao-Peng

    2007-01-01

    The growth rate of diamond has been investigated for a long time and researchers have been attempting to enhance the growth rate of high-quality gem diamond infinitely. However, it has been found according to previous research results that the quality of diamond is debased with the increase of growth rate. Thus, under specific conditions, the growth rate of high-quality diamond cannot exceed a limited value that is called the limited growth rate of diamond. We synthesize a series of type Ib gem diamonds by temperature gradient method under high pressure and high temperature (HPHT) using the as-grown {100} face. The dependence of limited growth rate on growth conditions is studied. The results show that the limited growth rate increases when synthetic temperature decreases, also when growth time is prolonged.

  17. GEM detector development for tokamak plasma radiation diagnostics: SXR poloidal tomography

    Science.gov (United States)

    Chernyshova, Maryna; Malinowski, Karol; Ziółkowski, Adam; Kowalska-Strzeciwilk, Ewa; Czarski, Tomasz; Poźniak, Krzysztof T.; Kasprowicz, Grzegorz; Zabołotny, Wojciech; Wojeński, Andrzej; Kolasiński, Piotr; Krawczyk, Rafał D.

    2015-09-01

    An increased attention to tungsten material is related to a fact that it became a main candidate for the plasma facing material in ITER and future fusion reactor. The proposed work refers to the studies of W influence on the plasma performances by developing new detectors based on Gas Electron Multiplier GEM) technology for tomographic studies of tungsten transport in ITER-oriented tokamaks, e.g. WEST project. It presents current stage of design and developing of cylindrically bent SXR GEM detector construction for horizontal port implementation. Concept to overcome an influence of constraints on vertical port has been also presented. It is expected that the detecting unit under development, when implemented, will add to the safe operation of tokamak bringing creation of sustainable nuclear fusion reactors a step closer.

  18. New High-Resolution Gadolinium-GEM Neutron Detectors for the NMX Instrument at ESS

    CERN Document Server

    Pfeiffer, Dorothea; Birch, Jens; Etxegarai, Maddi; Hall-Wilton, Richard; Höglund, Carina; Hultman, Lars; Llamas-Jansa, Isabel; Oliveri, Eraldo; Oksanen, Esko; Robinson, Linda; Ropelewski, Leszek; Schmidt, Susann; Streli, Christina; Thuiner, Patrik

    2016-01-01

    European Spallation Source instruments like the macromolecular diffractometer, NMX, require an excellent neutron detection efficiency, high-rate capabilities, time resolution, and an unprecedented spatial resolution in the order of a few hundred micrometers over a wide angular range of the incoming neutrons. For these instruments solid converters in combination with Micro Pattern Gaseous Detectors (MPGDs) are a promising option. A GEM detector with gadolinium converter was tested on a cold neutron beam at the IFE research reactor in Norway. The {\\mu}TPC analysis, proven to improve the spatial resolution in the case of $^{10}$B converters, is extended to gadolinium based detectors. For the first time, a Gd-GEM was successfully operated to detect neutrons with an estimated efficiency of 10% at a wavelength of 2 {\\AA} and a position resolution better than 350 {\\mu}m.

  19. BoNus: Development and use of a radial TPC using cylindrical GEMs

    International Nuclear Information System (INIS)

    A specialized system of target and detector was developed at Jefferson Lab to provide new access to information about neutron structure from electron-neutron interactions. It allows identification and measurement of spectator protons produced in e-d→e-psX scattering events. The detector is a radial time-projection chamber optimized for the acceptance of low-momentum protons. Gas gain is provided by three cascaded curved Gas Electron Multipliers (GEMs), the first application of GEMs in any configuration other than flat. This article provides details about the development and construction of the detector, its performance, and the analysis of the data from the successful running of its first physics experiment

  20. TPC-like readout for thermal neutron detection using a GEM-detector

    CERN Document Server

    Flierl, Bernhard; Hertenberger, Ralf; Zeitelhack, Karl

    2015-01-01

    Spatial resolution of less than 200 um is challenging for thermal neutron detection. A novel readout scheme based on the time-projection-chamber (TPC) concept is used in a gaseous electron multiplier (GEM) detector. Thermal neutrons are captured in a single 2 um thick Boron-10 converter cathode and secondary Helium and Lithium ions are produced with a combined energy of 2.8 MeV. These ions have sufficient energy to form straight tracks of several mm length. With a time resolving 2-dimensional readout of 400 um pitch in both directions, based on APV25 chips, the ions are tracked and their respective origin in the cathode converter foil is reconstructed. Using an Ar-CO2 93:7% gas mixture, a resolution of 100 um (FWHM 235 um) has been observed with a triple GEM-detector setup at the Garching neutron source (FRMII) for neutrons of 4.7 Angstrom.

  1. Investigations of the long-term stability of a GEM-TPC

    Energy Technology Data Exchange (ETDEWEB)

    Fedorchuk, Oleksiy [DESY, Hamburg (Germany); Collaboration: LCTPC-Deutschland-Collaboration

    2015-07-01

    For the International Large Detector (ILD) at the planned International Linear Collider (ILC), a Time Projection Chamber (TPC) is foreseen as the main tracking detector. The gas amplification will be done by Micro Pattern Gaseous Detectors (MPGD). One option is to use Gas Electron Multipliers (GEM). While the applicability of GEMs for the gas amplification in a TPC readout has been shown, the focus of the current research is to improve the stability and reliability of the readout modules. This is a crucial requirement for the operation in the final ILD TPC. This presentation shows results from precise discharge current measurements and parallel optical investigations. Ways to improve the long-term stability of the amplification system have been studied.

  2. Optically read out GEM-based TPC operation and preliminary scintillation studies

    CERN Document Server

    Galgoczi, Gabor

    2016-01-01

    The main goal of this project was to realise the reconstruction of tracks in an optically read out GEM (Gas Electron Multiplier) based Time Projection Chamber (TPC). Secondary goal was to initialise a series of systematic studies on the scintillation of particles in Ar/CF4 (80-20%) mixture. Track reconstruction is needed for primary scintillation studies as only tracks fully contained can be considered. A vetoing and trigerring logic was built for the TPC from NIM modules.

  3. Perceived Psychological Contract and Job Satisfaction of Secondary School Teachers in Gem District, Kenya

    OpenAIRE

    Mande Wycliffe Odhiambo

    2015-01-01

    The objective of the study was to determine the relationship between psychological contract and job satisfaction of secondary school teachers in Gem district, Kenya. A descriptive survey design was used with the target population of 400 teachers in public secondary schools. Stratified random sampling technique was used to come up with a total sample size of 200. Questionnaires with open ended and closed ended questions were developed by the researcher and used in primary data collection. The ...

  4. Malaysia International Jewellery and Gems Fair (IJG05) Unveiled in Style

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

      "Diamonds are a girl's best friend." This is certainly not an overstatement as women of all ages and ethnicity flocked to the much awaited annual jewellery extravaganza-Malaysia International Jewellery and Gems Fair (IJG'05) which was officially launched in style by Her Highness, Y.A.M. Tunku Dara Tunku Tan Sri Naquiah binti Tuanku Ja' afar earlier today at the swanky Mandarin Oriental Hotel, Kuala Lumpur.……

  5. Malaysia International Jewellery and Gems Fair (IJG05) Unveiled in Style

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    @@ "Diamonds are a girl's best friend." This is certainly not an overstatement as women of all ages and ethnicity flocked to the much awaited annual jewellery extravaganza-Malaysia International Jewellery and Gems Fair (IJG'05) which was officially launched in style by Her Highness, Y.A.M. Tunku Dara Tunku Tan Sri Naquiah binti Tuanku Ja' afar earlier today at the swanky Mandarin Oriental Hotel, Kuala Lumpur.

  6. Emissions from Petrol Engine Fueled Gasoline–Ethanol–Methanol (GEM) Ternary mixture as Alternative Fuel

    OpenAIRE

    Thangavelu Saravana Kannan; Chelladorai Piraiarasi; Ani Farid Nasir

    2015-01-01

    The increasing demands of petroleum fuels due to the rapid development automotive society coupled with the environmental pollution issues have inspired the efforts on exploring alternative fuels for internal combustion engines. Bioethanol obtained from biomass and bioenergy crops has been proclaimed as one of the feasible alternative to gasoline. In this study, the effect of gasoline–ethanol–methanol (GEM) ternary blend on the emission characteristics of petrol engine was studied. Three diffe...

  7. Performance of the full size nGEM detector for the SPIDER experiment

    Science.gov (United States)

    Muraro, A.; Croci, G.; Albani, G.; Claps, G.; Cavenago, M.; Cazzaniga, C.; Dalla Palma, M.; Grosso, G.; Murtas, F.; Pasqualotto, R.; Perelli Cippo, E.; Rebai, M.; Tardocchi, M.; Tollin, M.; Gorini, G.

    2016-03-01

    The ITER neutral beam test facility under construction in Padova will host two experimental devices: SPIDER, a 100 kV negative H/D RF beam source, and MITICA, a full scale, 1 MeV deuterium beam injector. SPIDER will start operations in 2016 while MITICA is expected to start during 2019. Both devices feature a beam dump used to stop the produced deuteron beam. Detection of fusion neutrons produced between beam-deuterons and dump-implanted deuterons will be used as a means to resolve the horizontal beam intensity profile. The neutron detection system will be placed right behind the beam dump, as close to the neutron emitting surface as possible thus providing the map of the neutron emission on the beam dump surface. The system uses nGEM neutron detectors. These are Gas Electron Multiplier detectors equipped with a cathode that also serves as neutron-proton converter foil. The cathode is designed to ensure that most of the detected neutrons at a point of the nGEM surface are emitted from the corresponding beamlet footprint (with dimensions of about 40×22 mm2) on the dump front surface. The size of the nGEM detector for SPIDER is 352 mm×200 mm. Several smaller size prototypes have been successfully made in the last years and the experience gained on these detectors has led to the production of the full size detector for SPIDER during 2014. This nGEM has a read-out board made of 256 pads (arranged in a 16×16 matrix) each with a dimension of 22 mm×13 mm. This paper describes the production of this detector and its tests (in terms of beam profile reconstruction capability, uniformity over the active area, gamma rejection capability and time stability) performed on the ROTAX beam-line at the ISIS spallation source (Didcot-UK).

  8. Effekt einer ad libitum verzehrten fettreduzierten Kost, reich an Obst, Gemüse und Milchprodukten auf den Blutdruck bei Borderline-Hypertonikern

    Science.gov (United States)

    Möseneder, Jutta M.

    2002-01-01

    In der randomisierten, multizentrischen DASH-Studie (Dietary Approaches to Stop Hy-pertension), die unter kontrollierten Bedingungen stattfand, führte eine fettreduzierte Mischkost, reich an Obst, Gemüse und Milchprodukten, bei Borderline-Hypertonikern zu einer signifikanten Blutdrucksenkung. Während der Studienphase wurden Körpermasse, Natrium-Aufnahme sowie Alkoholzufuhr aufgrund der bekannten Einflussnahme auf den Blutdruck konstant gehalten. In der eigenen Pilot-Studie sollte untersucht werden, ob das Ergebnis der DASH-Studie (i) mit deutschen Hypertonikern und (ii) unter habituellen Ernährungs- und Lebensbedingungen mit regelmäßig durchgeführter Ernährungsberatung und ad libitum Verzehr anstelle des streng kontrollierten Studienansatzes bestätigt werden kann. Eine Konstanz der Körpermasse, der Natrium-Urinausscheidung (unter diesem Studienansatz valider als die Aufnahme) und des Alkoholkonsums wurde vorausgesetzt. Die Studienpopulation setzte sich aus 53 übergewichtigen Probanden mit einer nicht medikamentös therapierten Borderline-Hypertonie und ohne Stoffwechselerkrankungen zusammen. Die Studienteilnehmer wurden randomisiert entweder der Idealgruppe mit einer fettarmen Kost reich an Milchprodukten, Obst und Gemüse (ähnlich der DASH-Idealgruppe) oder der Kontrollgruppe mit habitueller Ernährungsweise zugeteilt. Über einen Zeitraum von fünf Wochen wurde den Probanden etwa 50% ihres täglichen Lebensmittelbedarfes entsprechend ihrer Gruppenzugehörigkeit kostenfrei zur Verfügung gestellt. Gelegenheitsblutdruckmessungen und 24h-Blutdruckmessungen, Ernährungs- und Aktivitätsprotokolle, Blut- und Urinproben sowie anthropometrische Messungen wurden vor, während und fünf Wochen nach der Interventionsphase durchgeführt. Die Ergebnisse zeigen, dass in der Idealgruppe keine signifikante Blutdrucksenkung beobachtet werden konnte. Dies lässt sich durch die Tatsache erklären, dass die Lebens-mittel- und Nährstoffaufnahme der deutschen

  9. Zum Tragverhalten von mehrschichtigen Glaselementen mit integrierten Funktionsträgern am Beispiel von Glaslamellen mit eingebetteten Hologrammen

    OpenAIRE

    Topp, Thomas

    2008-01-01

    Glasfassaden werden neben den originären Aufgaben der Belichtung und des Gebäudeabschlusses, in zunehmendem Maße mit weiteren Funktionen ausgestattet. Die dafür notwendigen Funktionselemente sind überwiegend als Folien ausgebildet und in die Funktionsschichten von Verbundgläsern integriert. Es entstehen mehrschichtige Funktionsgläser mit einem Potenzial für Verbundtragwirkung. Die sichere Identifizierung dieses Tragverhaltens im Hinblick auf eine wirtschaftliche Dimensionierung für größere Sp...

  10. Performance Verification of the Gravity and Extreme Magnetism Small Explorer GEMS X-Ray Polarimeter

    Science.gov (United States)

    Enoto, Teruaki; Black, J. Kevin; Kitaguchi, Takao; Hayato, Asami; Hill, Joanne E.; Jahoda, Keith; Tamagawa, Toru; Kanako, Kenta; Takeuchi, Yoko; Yoshikawa, Akifumi; Kenward, David

    2014-01-01

    olarimetry is a powerful tool for astrophysical observations that has yet to be exploited in the X-ray band. For satellite-borne and sounding rocket experiments, we have developed a photoelectric gas polarimeter to measure X-ray polarization in the 2-10 keV range utilizing a time projection chamber (TPC) and advanced micro-pattern gas electron multiplier (GEM) techniques. We carried out performance verification of a flight equivalent unit (1/4 model) which was planned to be launched on the NASA Gravity and Extreme Magnetism Small Explorer (GEMS) satellite. The test was performed at Brookhaven National Laboratory, National Synchrotron Light Source (NSLS) facility in April 2013. The polarimeter was irradiated with linearly-polarized monochromatic X-rays between 2.3 and 10.0 keV and scanned with a collimated beam at 5 different detector positions. After a systematic investigation of the detector response, a modulation factor greater than or equal to 35% above 4 keV was obtained with the expected polarization angle. At energies below 4 keV where the photoelectron track becomes short, diffusion in the region between the GEM and readout strips leaves an asymmetric photoelectron image. A correction method retrieves an expected modulation angle, and the expected modulation factor, approximately 20% at 2.7 keV. Folding the measured values of modulation through an instrument model gives sensitivity, parameterized by minimum detectable polarization (MDP), nearly identical to that assumed at the preliminary design review (PDR).

  11. A simulation study on angular and micro pattern effects in GEM detectors.

    Science.gov (United States)

    Kim, H G; Jamil, M; Rhee, J T; Ahmad, Farzana; Jeon, Y J

    2016-04-01

    A useful approach for the enhancement of thermal neutrons detection has been reported here. This technique, based on the angular and micro pattern effects, has been developed and applied to the boron-coated ((10)B) Gas Electron multiplier (GEM) detector. In the angular effect case, as a general rule, the detector device is turned at an angle which improves the device response per unit area of the detector. While for the latter case, a regular pattern in the form of micrometer deep grooves is fabricated onto the converter coating, consequently it enhances the capture probability of the detector. For the current study, both of these techniques using a (10)B-coated GEM detector have been simulated for low energy neutrons. For the evaluation of detector response thermal neutrons in the energy ranges from 25meV to 100meV were transported onto the detector surface. For this work, FLUKA MC code has been utilized. The output in both cases has been estimated as a function of incident thermal neutron energies. By employing both techniques, the angle and the micro pattern dependent efficiencies for (10)B-coated GEM detectors are presented, which indicate an improved efficiency response of the device. We anticipate that by using these modifications can lead a further forward step in the development and improvement of thermal neutron detection technology. PMID:26773818

  12. First evidence of hydrous silicic fluid films around solid inclusions in gem-quality diamonds

    Science.gov (United States)

    Nimis, Paolo; Alvaro, Matteo; Nestola, Fabrizio; Angel, Ross J.; Marquardt, Katharina; Rustioni, Greta; Harris, Jeff W.; Marone, Federica

    2016-09-01

    Diamonds form from fluids or melts circulating at depth in the Earth's mantle. Analysis of these fluids is possible if they remain entrapped in the diamond during its growth, but this is rarely observed in gem-quality stones. We provide the first evidence that typical mineral inclusions in gem-quality diamonds from the Siberian and Kaapvaal cratons are surrounded by a thin film of hydrous silicic fluid of maximum thickness 1.5 μm. The fluid contains Si2O(OH)6, Si(OH)4, and molecular H2O and was identified using confocal micro-Raman spectroscopy and synchrotron-based X-ray tomographic microscopy. As the solid mineral inclusions have both peridotitic and eclogitic affinities and occur in two cratonic regions, our results demonstrate the strong connection between water-rich fluids and the growth of gem-quality lithospheric diamonds. The presence of the fluid films should be taken into account for a proper evaluation of H2O contents in the mantle based on H2O contents in solid inclusions and for a robust assessment of diamond formation pressures based on the residual pressures of the inclusions.

  13. Performances of a GEM-based Time Projection Chamber prototype for the AMADEUS experiment

    CERN Document Server

    Lener, M Poli; Corradi, G; Curceanu, C; D'Uffizi, A; Paglia, C; Vidal, A Romero; Sbardella, E; Scordo, A; Tagnani, D; Zmeskal, J

    2013-01-01

    A large number of high-energy and heavy-ion experiments successfully used Time Projection Chamber (TPC) as central tracker and particle identification detector. However, the performance requirements on TPC for new high-rate particle experiments greatly exceed the abilities of traditional TPC read out by multi-wire proportional chamber (MWPC). Gas Electron Multiplier (GEM) detector has great potential to improve TPC performances when used as amplification device. In this paper we present the R&D activity on a new GEM-based TPC detector built as a prototype for the inner part for AMADEUS, a new experimental proposal at the DAFNE collider at Laboratori Nazionali di Frascati (INFN), aiming to perform measurements of the low-energy negative kaons interactions in nuclei. In order to evaluate the GEM-TPC performances, a 10x10 cm2 prototype with a drift gap up to 15 cm has been realized. The detector was tested at the pM1 beam facility of the Paul Scherrer Institut (PSI) with low momentum pions and protons, witho...

  14. The 2.3 GHz continuum survey of the GEM project

    CERN Document Server

    Tello, C; Torres, S; Bersanelli, M; Smoot, G F; Ferreira, I S; Cingoz, A; Lamb, J; Barbosa, D; Perez-Becker, D; Ricciardi, S; Currivan, J A; Platania, P; Maino, D

    2007-01-01

    In this paper we present the scope of the Galactic Emission Mapping (GEM) project and its results at 2.3 GHz. Its observational program was conceived and developed to reveal the large scale properties of Galactic synchrotron radiation in total intensity and polarisation through a self-consistent set of radio continuum surveys between 408 MHz and 10 GHz. GEM's unique observational strategy and experimental design aim at the production of foreground templates in order to address the mutual inconsistencies between existing surveys and the role of Galactic emission as the main source of astrophysical contamination in measurements of the Cosmic Microwave Background radiation. The GEM experiment uses a portable and double-shielded 5.5-m radiotelescope on a rotating platform to map 60 deg wide declination bands, from different observational sites, by circularly scanning the sky at 30 deg from the Zenith. The observations at 2.3 GHz were accomplished with a total power receiver, whose front-end HEMT was matched direc...

  15. ULTRAVIOLET SPECTROSCOPY OF PQ Gem AND V405 Aur FROM THE HST AND IUE SATELLITES

    Energy Technology Data Exchange (ETDEWEB)

    Sanad, M. R., E-mail: mrsanad1@yahoo.com [National Research Institute of Astronomy and Geophysics, Astronomy Department, Helwan—Cairo— Egypt (Egypt)

    2015-10-20

    Ultraviolet spectra of two intermediate polars (IPs), PQ Gem and V405 Aur, observed with Hubble Space Telescope (HST) Space Telescope Imaging Spectrograph and Faint Object Spectrograph and International Ultraviolet Explorer (IUE) satellites were analyzed during the period between 1994–2000. We estimated the reddening of the two systems from the 2200 Å feature. Six spectra of the two systems revealing modulations of line fluxes at different times are presented. PQ Gem and V405 Aur are featured by spectral lines in different ionization states. This paper focuses on the third ionized carbon emission line at 1550 Å and the first ionized helium emission line at 1640 Å produced in the optically thin outer region of the accretion curtain for the two systems by calculating spectral line fluxes. From HST and IUE data, we deduced ultraviolet luminosities and ultraviolet accretion rates for the two binary stars. The average temperature of the accretion streams for PQ Gem and V405 Aur are ∼4500 K and 4100 K, respectively. The results reveal that there are modulations in fluxes of spectral lines, ultraviolet luminosities, and ultraviolet accretion rates with time for both systems. These modulations are referred to the changes of both density and temperature as a result of the variations of mass transfer rate from the secondary star to the primary star. The current results are consistent with an accretion curtain model for IPs.

  16. R&D on GEM Detectors for Forward Tracking at a Future Electron-Ion Collider

    CERN Document Server

    Zhang, Aiwu; Hohlmann, Marcus; Bai, Xinzhan; Gnanvo, Kondo; Liyanage, Nilanga K; Posik, Matt; Surrow, Bernd

    2015-01-01

    We report the status of R&D on large triple-GEM detectors for a forward tracker (FT) in an experiment at a future Electron Ion Collider (EIC) that will improve our understanding of QCD. We have designed a detector prototype specifically targeted for the EIC-FT, which has a trapezoidal shape with 30.1 degrees opening angle. We are investigating different detector assembly techniques and signal readout technologies, but have designed a common GEM foil to minimize NRE cost for foil production. The assembly techniques comprise either a purely mechanical method including foil stretching as pioneered by CMS but with certain modifications, or gluing foils to frames that are then assembled mechanically, or gluing foils to frames that are then glued together. The first two assembly techniques allow for re-opening chambers so that a GEM foil can be replaced if it is damaged. For readout technologies, we are pursuing a cost-effective one-dimensional readout with wide zigzag strips that maintains reasonable spatial r...

  17. GEM, Fuel Cycle Cost and Economics for Thermal Reactor, Present Worth Analysis

    International Nuclear Information System (INIS)

    1- Description of problem or function: GEM is used to predict fuel cycle costs for any type nuclear system (i.e., BWR, HTGR, PWR, LMFBR, GCFR,... ). The current version is limited to thermal reactors. GEM is designed for production use by large utilities which have several reactor types on their system. GEM has been written so as to accommodate all major fuel management activities undertaken by a utility - (1) fuel bid analysis, (2) evaluation of actual day to day operation, and (3) system simulation and optimization studies. 2 - Method of solution: Costs are calculated using present-worth techniques and continuous compounding. The equations are based on an investor-owned utility capitalization structure which easily covers the range of industrial, private, and public (government) owned utilities. Three distinct types of analysis (cash flow, allocated costs, yearly cash flow) are performed, each yielding identical results. Using these as a basis many other analyses are undertaken. 3 - Restrictions on the complexity of the problem: Dimensions of all arrays are carried as variables throughout the analysis. The maximum size of each array is set by the user in program MAIN. Current values are set so that maxima are: 50 batches per case study, 20 year batch life, 30 year case study, 120 batch burn time-steps, 20 individual payments (sales) associated with each cost component

  18. The HadGEM2-ES implementation of CMIP5 centennial simulations

    Directory of Open Access Journals (Sweden)

    C. D. Jones

    2011-03-01

    Full Text Available The scientific understanding of the Earth's climate system, including the central question of how the climate system is likely to respond to human-induced perturbations, is comprehensively captured in GCMs and Earth System Models(ESM. Diagnosing the simulated climate response, and comparing responses across different models, is crucially dependent on transparent assumptions of how the GCM/ESM has been driven – especially because the implementation can involve subjective decisions and may differ between modelling groups performing the same experiment. This paper outlines the climate forcings and setup of the Met Office Hadley Centre ESM, HadGEM2-ES for the CMIP5 set of centennial experiments. We document the prescribed greenhouse gas concentrations, aerosol precursors, stratospheric and tropospheric ozone assumptions, as well as implementation of land-use change and natural forcings for the HadGEM2-ES historical and future experiments following the Representative Concentration Pathways. In addition, we provide details of how HadGEM2-ES ensemble members were initialised from the control run and how the palaeoclimate and AMIP experiments, as well as the "emission-driven" RCP experiments were performed.

  19. Menschen mit Demenz als Interaktionspartner. Eine Auswertung empirischer Studien vor dem Hintergrund eines dimensionalisierten Interaktionsbegriffs

    OpenAIRE

    Meyer, Christian

    2014-01-01

    Der Anteil von Menschen mit Demenz an der Gesamtbevölkerung Deutschlands wird mittelfristig stark zunehmen und die Begegnung mit Betroffenen aufgrund persönlicher und familiärer Kontakte zu einem alltäglichen Teil der Gesellschaft werden. Angesichts der spezifischen Symptomatik der Demenz – insbesondere des sukzessiven Verlusts des deklarativen und biografischen (episodischen) Gedächtnisses – stellt sich die Frage, wie sich soziale Interaktion mit Menschen mit Demenz gestaltet, und ob in solc...

  20. Das Erkennen mimisch kodierter Basisemotionen durch Patienten mit Panikstörung

    OpenAIRE

    Bruckner, Julia

    2009-01-01

    Ziel unserer Untersuchung war es, Defizite der Emotionserkennung zu untersuchen und die Einflüsse auf die Emotionserkennungsfähigkeit bei Patienten mit Panikstörung zu erfassen. An der Untersuchung nahmen 37 Patienten mit Panikstörung und 43 Patienten mit leichteren neurologischen Erkrankungen teil, sie absolvierten hierbei den computergestützten FEEL-Test (Facially Expressed Emotion Labeling). Ergebnisse: Patienten mit Panikstörung weisen im Vergleich zu psychisch gesunden Kontrollp...

  1. Ein Konzept für die merkmalsbasierte Tumor-Klassifikation mit diagnostischem Ultraschall

    OpenAIRE

    Siebers, Stefan

    2008-01-01

    Die Bildgebung mit Ultraschall (Sonographie) hat sich zu der am häufigsten verwendeten medizinischen Bildgebungsmodalität entwickelt. Eine Unterscheidung gut- und bösartiger Tumoren mit Hilfe der Sonographie setzt allerdings große Erfahrung beim Untersucher voraus und gilt als außerordentlich schwierig. In dieser Arbeit wurde daher ein Konzept zur automatisierten Klassifikation mit diagnostischem Ultraschall entwickelt und im Rahmen einer klinischen Studie mit 138 Fällen zur Digni...

  2. Analyse von Arbeitsplätzen auf halbautomatischen Pflanzmaschinen mit Hilfe von MTM (Methods Time Measurement)

    OpenAIRE

    Remmele, Edgar

    2014-01-01

    Mit Hilfe von MTM (Methods Time Measurement), einem System vorbestimmter Zeiten, werden Bewegungsstudien an drei verschiedenen halbautomatischen Pflanzmaschinen durchgeführt. Hauptunterscheidungsmerkmal der untersuchten Pflanzmaschinen ist die Methode der Übergabe der Pflanze von der Pflanzperson an die Pflanzmaschine. Analysiert wird der Arbeitsplatz der Pflanzmaschine ACCORD-Standard mit der Methode Klemmscheibe, PES-Beetpflanzer 1500/1900 mit der Methode Pflanzfinger und Lännen RT-2 mit de...

  3. Interaktion mit RFID Ausleih- und Rückgabeautomaten

    DEFF Research Database (Denmark)

    Greifeneder, Elke; Heyroth, Melanie; Klingbeil, Karin;

    2011-01-01

    Der Artikel untersucht mittels Beobachtung die Interaktion zwischen RFID-Ausleih- und Rückgabeautomaten sowie Bibliotheksbenutzern in vier deutschen Bibliotheken. Die Ergebnisse belegen, dass die Interaktion grundsätzlich funktioniert. Die Benutzer zeigten Gelassenheit und Routine im Umgang mit den...

  4. Stiff lightweight steel constructions; Steife Leichtbauweise mit Stahl

    Energy Technology Data Exchange (ETDEWEB)

    Gerick, A.; Lempenauer, K. [Daimler Benz AG, Ulm (Germany). Forschungszentrum; Hauger, A.; Kopp, R. [Technische Hochschule Aachen (Germany). Inst. fuer Bildsame Formgebung

    1999-07-01

    Compared with welded sheets of composite materials, glued sheets have much better deformation characteristics. This was the result of experiments carried out by the authors. Further investigation will focus on the integration of the sheets in a car body by welding, the long-term strength of welds, the applicability of bolting or riveting techniques, and the fatigue strength of the car body under oscillating stress. [German] Durch die Verwendung von Klebefolien bzw. Klebstoffen auf Epoxidharz-Basis und einem optimierten Herstellungs- und Verarbeitungsprozess konnten im Vergleich mit geschweissten Verbundblechen erheblich groessere Umformgrade erzielt werden. Anhand von Erichsen-Tiefungen und Grenzformaenderungsschaubildern wurde dies aufgezeigt. Dabei wurde eine gute Streckzieh- und insbesonders gute Tiefziehfaehigkeit festgestellt. Mittels 4-Punkt-Biegeversuchen wurde die Gesamtbiegesteifigkeit der Verbunde ermittelt. Fuer alle Verbundvariationen wurde eine deutliche Gewichtsreduktion gegenueber Massivstahlblechen nachgewiesen. Sogar im Vergleich zu Massivaluminiumblechen lassen sich mit Streckmetallverbunden Gewichtsvorteile erreichen. Mit Hilfe der elementaren Theorie und einem Modell zur Berechnung des Traegheitsmomentes kann das tatsaechliche Biegeverhalten der Verbundstrukturen in guter Naeherung berechnet werden. Insgesamt hat sich gezeigt, dass das Ziel, umformbare und biegesteife Blechsandwiche darzustellen, mit einem geklebten Streckmetallverbundblech im Hinblick auf das genaue Anforderungsprofil weitgehend zu erreichen ist. In weiterfuehrenden Untersuchungen werden insbesondere die Anbindung an die Gesamtstruktur einer Karosserie durch Schweissverfahren, die Dauerfestigkeit von Schweissverbindungen, die Anwendbarkeit von mechanischen Fuegeverfahren (Setzverhalten von Schraub- und Nietverbindungen) und die Schwingfestigkeit des Verbundes naeher betrachtet. (orig.)

  5. Past, present and future of MIT reactor physics

    International Nuclear Information System (INIS)

    The reactor physics curriculum at MIT has been undergoing lots of changes in recent years. This paper describes the course sequence and philosophy that we have implemented and continue to develop. Additionally, thoughts on future direction with respect to modularity and web-based learning are presented. (author)

  6. Numerische Berechnung von Wirbelstromproblemen mit der Cell-Methode

    Directory of Open Access Journals (Sweden)

    K. Frenner

    2006-01-01

    Full Text Available In dieser Arbeit wird die Cell-Methode auf die quasistatischen Maxwellgleichungen angewendet. Dabei werden für die notwendige Transformation vom Primärgitter auf das duale Gitter reziproke Basisvektoren verwendet. Anhand der Felddiffusion der magnetischen Induktion in einen zylindrischen Leiter werden Ergebnisse der Cell-Methode mit einer analytischen Vergleichsrechnung präsentiert.

  7. MIT Mints a Valuable New Form of Academic Currency

    Science.gov (United States)

    Carey, Kevin

    2012-01-01

    The Massachusetts Institute of Technology (MIT) has invented or improved many world-changing things--radar, information theory, and synthetic self-replicating molecules, to name a few. Last month the university announced, to mild fanfare, an invention that could be similarly transformative, this time for higher education itself. It is called MITx.…

  8. Wie ich mich mit dem äthiopischen Regime anlegte

    DEFF Research Database (Denmark)

    Hagmann, Tobias

    2016-01-01

    Als Forscher und Kritiker der äthiopischen Politik habe ich viel über das Verhältnis gelernt, in dem Wahrheit und Macht, aber auch Moral und persönliche Interessen zueinander stehen. In den Niederungen der Realpolitik wird mit harten Bandagen um die Deutungshoheit gekämpft wird. Auch Wissenschafter...

  9. Very Short Bunches in MIT-Bates South Hall Ring

    CERN Document Server

    Wang, Dong; Farkhondeh, Manouchehr; Franklin, Wilbur; Graves, William; Ihloff, Ernie; Podobedov, Boris; Tschalär, C; Wang, Defa; Wang, Fuhua; Zwart, Townsend; van der Laan, Jan

    2005-01-01

    The study of ultra-short bunches in MIT SHR storage ring with very small momentum compactions is carried out. The ultra-short bunches are to greatly enhence the coherent radiation by many orders of magnitude. The ring lattice is resigned to reach very small momentum compaction factor down to 1·10-5

  10. Parallelization experience with four canonical econometric models using ParMitISEM

    NARCIS (Netherlands)

    Baştürk, N.; Grassi, S.; Hoogerheide, L.; van Dijk, H.K.

    2016-01-01

    This paper presents the parallel computing implementation of the MitISEM algorithm, labeled Parallel MitISEM. The basic MitISEM algorithm, introduced by Hoogerheide et al. (2012), provides an automatic and flexible method to approximate a non-elliptical target density using adaptive mixtures of Stud

  11. GEM-E3: A computable general equilibrium model applied for Switzerland

    Energy Technology Data Exchange (ETDEWEB)

    Bahn, O. [Paul Scherrer Inst., CH-5232 Villigen PSI (Switzerland); Frei, C. [Ecole Polytechnique Federale de Lausanne (EPFL) and Paul Scherrer Inst. (Switzerland)

    2000-01-01

    The objectives of the European Research Project GEM-E3-ELITE, funded by the European Commission and coordinated by the Centre for European Economic Research (Germany), were to further develop the general equilibrium model GEM-E3 (Capros et al., 1995, 1997) and to conduct policy analysis through case studies. GEM-E3 is an applied general equilibrium model that analyses the macro-economy and its interaction with the energy system and the environment through the balancing of energy supply and demand, atmospheric emissions and pollution control, together with the fulfillment of overall equilibrium conditions. PSI's research objectives within GEM-E3-ELITE were to implement and apply GEM-E3 for Switzerland. The first objective required in particular the development of a Swiss database for each of GEM-E3 modules (economic module and environmental module). For the second objective, strategies to reduce CO{sub 2} emissions were evaluated for Switzerland. In order to develop the economic, PSI collaborated with the Laboratory of Applied Economics (LEA) of the University of Geneva and the Laboratory of Energy Systems (LASEN) of the Federal Institute of Technology in Lausanne (EPFL). The Swiss Federal Statistical Office (SFSO) and the Institute for Business Cycle Research (KOF) of the Swiss Federal Institute of Technology (ETH Zurich) contributed also data. The Swiss environmental database consists mainly of an Energy Balance Table and of an Emission Coefficients Table. Both were designed using national and international official statistics. The Emission Coefficients Table is furthermore based on know-how of the PSI GaBE Project. Using GEM-E3 Switzerland, two strategies to reduce the Swiss CO{sub 2} emissions were evaluated: a carbon tax ('tax only' strategy), and the combination of a carbon tax with the buying of CO{sub 2} emission permits ('permits and tax' strategy). In the first strategy, Switzerland would impose the necessary carbon tax to achieve

  12. GEM-E3: A computable general equilibrium model applied for Switzerland

    International Nuclear Information System (INIS)

    The objectives of the European Research Project GEM-E3-ELITE, funded by the European Commission and coordinated by the Centre for European Economic Research (Germany), were to further develop the general equilibrium model GEM-E3 (Capros et al., 1995, 1997) and to conduct policy analysis through case studies. GEM-E3 is an applied general equilibrium model that analyses the macro-economy and its interaction with the energy system and the environment through the balancing of energy supply and demand, atmospheric emissions and pollution control, together with the fulfillment of overall equilibrium conditions. PSI's research objectives within GEM-E3-ELITE were to implement and apply GEM-E3 for Switzerland. The first objective required in particular the development of a Swiss database for each of GEM-E3 modules (economic module and environmental module). For the second objective, strategies to reduce CO2 emissions were evaluated for Switzerland. In order to develop the economic, PSI collaborated with the Laboratory of Applied Economics (LEA) of the University of Geneva and the Laboratory of Energy Systems (LASEN) of the Federal Institute of Technology in Lausanne (EPFL). The Swiss Federal Statistical Office (SFSO) and the Institute for Business Cycle Research (KOF) of the Swiss Federal Institute of Technology (ETH Zurich) contributed also data. The Swiss environmental database consists mainly of an Energy Balance Table and of an Emission Coefficients Table. Both were designed using national and international official statistics. The Emission Coefficients Table is furthermore based on know-how of the PSI GaBE Project. Using GEM-E3 Switzerland, two strategies to reduce the Swiss CO2 emissions were evaluated: a carbon tax ('tax only' strategy), and the combination of a carbon tax with the buying of CO2 emission permits ('permits and tax' strategy). In the first strategy, Switzerland would impose the necessary carbon tax to achieve the reduction target, and use the tax

  13. Metal-mediated gem-Difluoroallylation of N-Acylhydrazones: Highly Efficient Synthesis of a,a-Difluorohomoallylic Amines

    Institute of Scientific and Technical Information of China (English)

    YUE Xuyi; QIU Xiaolong; QING Fengling

    2009-01-01

    Indium-mediated gem-difluoroallylation of aldehyde-derived N-acylhydrazones 1a-1q and 4a-4g with 3-bromo-3,3-difluoropropene 2 afforded a,a-difluorohomoallylic hydrazides 3a-3q and 5a-5g in high yields, re-spectively. Functional groups such as nitro, phenolic hydroxyl, benzyloxy and even C=C bonds of a,fl-unsaturated aldehydes were compatible under this mild and operationally simple gem-difluoroallylic reaction condition. By means of substitution of Zn powder for indium, gem-difluoroallylation of ketone-derived N-acylhydrazones 6a-6d also provided the corresponding a,a-difluorohomoallylic hydrazides 7a-7d in medium yields. The N-N bond cleavage of the hydrazide 3a proceeded smoothly to give the corresponding primary gem-difluorohomoallylic amine 8, which could be converted to gem-difluoro-δ-substituted α,β-unsaturated lactam 11 via acryloylation fol-lowed by ring closing metathesis (RCM) reaction.

  14. Design and implementation of the infrastructure of HadGEM3: the next-generation Met Office climate modelling system

    Directory of Open Access Journals (Sweden)

    H. T. Hewitt

    2011-04-01

    Full Text Available This paper describes the development of a technically robust climate modelling system, HadGEM3, which couples the Met Office Unified Model atmosphere component, the NEMO ocean model and the Los Alamos sea ice model (CICE using the OASIS coupler. Details of the coupling and technical solutions of the physical model (HadGEM3-AO are documented, in addition to a description of the configurations of the individual submodels. The paper demonstrates that the implementation of the model has resulted in accurate conservation of heat and freshwater across the model components. The model performance in early versions of this climate model is briefly described to demonstrate that the results are scientifically credible. HadGEM3-AO is the basis for a number of modelling efforts outside of the Met Office, both within the UK and internationally. This documentation of the HadGEM3-AO system provides a detailed reference for developers of HadGEM3-based climate configurations.

  15. Study of long-term operation of triple-GEM detectors for the high rate environment in CMS

    CERN Document Server

    Merlin, Jeremie Alexandre

    2013-01-01

    The CMS GEM collaboration is working on the possible instrumentation of the high-eta region of the CMS Endcap with Gas Electron Multiplier (GEM) detectors, a technology capable to sustain the hostile environment that will be encountered at the high-luminosity LHC. To ensure the long-term operation of large triple-GEM detectors in the CMS experiment, we are performing a set of studies in order to measure and understand the aging effect of triple-GEM Muon chambers. The aging includes all the processes that lead to a significant degradation of the performances of the detector gain drop, non-uniformity, dark current, discharges and resolution loss. The project is focused on monitoring continuously the response of the detector when irradiated by a source of Cs 137 at CERN in the Gamma Irradiation Facility (GIF). Moreover, the new technology employed for stretching the GEM foils, so called NS2, introduces new, carefully chosen materials and components in the detectors. Outgassing tests are performed in order to va...

  16. Supermarket refrigerators with natural refrigerants; Supermarktkaelteanlagen mit natuerlichen Kaeltemitteln. Erfahrungsbericht

    Energy Technology Data Exchange (ETDEWEB)

    Haaf, S.; Heinbokel, B. [Linde AG, Koeln (Germany). Gechaeftsbereich Linde Kaeltetechnik

    2002-09-01

    In view of the high contribution to global warming of H-CFC refrigerants, substitution has been a key concern for several years now. Leakage protection measures were enhanced, and Linde also installed many supermarket refrigerators with natural refrigerants, i.e. ammonia, propene and carbon dioxide. The environmental and economic aspects are assessed on the basis of the experience gained, and the systems are compared with H-CFC refrigeration systems. [German] Wegen des betraechtlichen Treibhauspotentials von HFKW-Kaeltemitteln werden seit Jahren Anstrengungen unternommen, um den von diesen Stoffen ausgehenden Treibhauseffekt zu reduzieren. Neben Massnahmen zur Verminderung von Leckagen sowie zur Verringerung von Kaeltemittel-Fuellmengen wurden im Laufe der letzten 10 Jahre von Linde auch zahlreiche Kaelteanlagen mit den natuerlichen Kaeltemitteln Ammoniak, Propen und Kohlendioxid in Supermaerkten installiert. Auf Basis der gesammelten Erfahrungen wird eine Einschaetzung der umweltspezifischen und wirtschaftlichen Aspekte im Vergleich zu Anlagen mit HFKW-Kaeltemitteln vorgenommen. (orig.)

  17. The MIT / NASA Langley Magnetic Suspension/Balance System

    Science.gov (United States)

    1991-01-01

    A shuttle model is magnetically suspended in the transparent octagonal test section of the MIT / NASA Langley 6 Inch MSBS. Massive power supplies are required to drive electromagnets for model position control. A unique electromagnetic position sensor, similar to a linear variable differential transformer, provides five degrees of freedom for the test model. The low speed (Mach 0.5) wind tunnel was hand crafted from mahogany. Aerodynamic forces on the test model are measured by the proportional electrical current used to hold the model in place. The system was built by MIT in the late sixties and was relocated to Langley in the mid eighties. In a joint effort with Old Dominion University in 1992 the MSBS was used to test the aerodynamics of store separation, simulating a bomb released from an aircraft. The system has been donated to Old Dominion University.

  18. Properties of hybrid stars in an extended MIT bag model

    Institute of Scientific and Technical Information of China (English)

    BAO Tmurbagan; LIU Guang-Zhou; ZHU Ming-Feng

    2009-01-01

    The properties of hybrid stars are investigated in the framework of the relativistic mean field theory (RMFT) and an MIT bag model with density-dependent bag constant to describe the hadron phase (HP) and quark phase (QP), respectively. We find that the density-dependent B(p) decreases with baryon density p; this decrement makes the strange quark matter become more energetically favorable than ever, which makes the threshold densities of the hadron-quark phase transition lower than those of the original bag constant case. In this case, the hyperon degrees of freedom can not be considered. As a result, the equations of state of a star in the mixed phase (MP) become softer whereas those in the QP become stiffer, and the radii of the star obviously decrease. This indicates that the extended MIT bag model is more suitable to describe hybrid stars with small radii.

  19. MIT LMFBR blanket research project. Final summary report

    Energy Technology Data Exchange (ETDEWEB)

    Driscoll, M.J.

    1983-08-01

    This is a final summary report on an experimental and analytical program for the investigation of LMFBR blanket characteristics carried out at MIT in the period 1969 to 1983. During this span of time, work was carried out on a wide range of subtasks, ranging from neutronic and photonic measurements in mockups of blankets using the Blanket Test Facility at the MIT Research Reactor, to analytic/numerical investigations of blanket design and economics. The main function of this report is to serve as a resource document which will permit ready reference to the more detailed topical reports and theses issued over the years on the various aspects of project activities. In addition, one aspect of work completed during the final year of the project, on doubly-heterogeneous blanket configurations, is documented for the record.

  20. MIT LMFBR blanket research project. Final summary report

    International Nuclear Information System (INIS)

    This is a final summary report on an experimental and analytical program for the investigation of LMFBR blanket characteristics carried out at MIT in the period 1969 to 1983. During this span of time, work was carried out on a wide range of subtasks, ranging from neutronic and photonic measurements in mockups of blankets using the Blanket Test Facility at the MIT Research Reactor, to analytic/numerical investigations of blanket design and economics. The main function of this report is to serve as a resource document which will permit ready reference to the more detailed topical reports and theses issued over the years on the various aspects of project activities. In addition, one aspect of work completed during the final year of the project, on doubly-heterogeneous blanket configurations, is documented for the record

  1. GEM-based TPC with CCD imaging for directional dark matter detection

    Science.gov (United States)

    Phan, N. S.; Lauer, R. J.; Lee, E. R.; Loomba, D.; Matthews, J. A. J.; Miller, E. H.

    2016-11-01

    The most mature directional dark matter experiments at present all utilize low-pressure gas Time Projection Chamber (TPC) technologies. We discuss some of the challenges for this technology, for which balancing the goal of achieving the best sensitivity with that of cost effective scale-up requires optimization over a large parameter space. Critical for this are the precision measurements of the fundamental properties of both electron and nuclear recoil tracks down to the lowest detectable energies. Such measurements are necessary to provide a benchmark for background discrimination and directional sensitivity that could be used for future optimization studies for directional dark matter experiments. In this paper we describe a small, high resolution, high signal-to-noise GEM-based TPC with a 2D CCD readout designed for this goal. The performance of the detector was characterized using alpha particles, X-rays, gamma-rays, and neutrons, enabling detailed measurements of electron and nuclear recoil tracks. Stable effective gas gains of greater than 1 × 105 were obtained in 100 Torr of pure CF4 by a cascade of three standard CERN GEMs each with a 140 μm pitch. The high signal-to-noise and sub-millimeter spatial resolution of the GEM amplification and CCD readout, together with low diffusion, allow for excellent background discrimination between electron and nuclear recoils down below ∼10 keVee (∼23 keVr fluorine recoil). Even lower thresholds, necessary for the detection of low mass WIMPs for example, might be achieved by lowering the pressure and utilizing full 3D track reconstruction. These and other paths for improvements are discussed, as are possible fundamental limitations imposed by the physics of energy loss.

  2. Cytogenetic monitoring of personnel occupationally exposed to microwave radiation of GEM radar

    International Nuclear Information System (INIS)

    In the present study we analyzed and followed-up on the DNA damaging effects of microwave radiation of GEM radar equipment within microwave field of 10 μW/cm2 to 10 mW/cm2 in personnel occupationally exposed to frequency range of 1.5 GHz to 10.9 GHz. The single cell gel electrophoresis (SCGE)/comet assay as a tool for the bio monitoring of individuals accidentally, environmentally or occupationally exposed to physical or chemical agents was used to evaluate possible genotoxic effect on peripheral human blood lymphocytes. The comet assay is a method that allows efficient determination of single strand breaks (SSB) and double-strand breaks (DSB), as well as alkali-labile sites in the DNA of single cells. The comet assay was carried out under alkaline conditions. We measured the baseline comet assay effect in whole blood samples. Parameter of the comet assay was studied in workers occupationally exposed to microwave radiation of GEM radar and in corresponding unexposed control subjects. It was found that in the subjects who were occupationally exposed to microwave radiation, the levels of DNA damage increased compare to control group and showed interindividual variations. As a measure of DNA damage tail length was used, calculated from the centre of the head and presented in micrometers (μm). Mean value of exposed group was 13.54±1.44 as opposed to control mean value that was 13.15±1.39. Differences between mean tail lengths were statistically significant (P<0.05, ANOVA). The results of this study indicate that individuals occupationally exposed to microwave frequency of GEM radar equipment may experience an increased genotoxic risk, emphasizing the importance of individual bio monitoring, limiting exposure and radiation safety programs. (author)

  3. First Year K-12 Teachers as High Leverage Point to Implement GEMS Space Science Curriculum Sequence

    Science.gov (United States)

    Slater, Timothy F.; Mendez, B. J.; Schultz, G.; Wierman, T.

    2013-01-01

    The recurring challenge for curriculum developers is how to efficiently prepare K-12 classroom teachers to use new curricula. First-year teachers, numbering nearly 250,000 in the US each year, have the greatest potential to impact the largest number of students because they have potential to be in the classroom for thirty years. At the same time, these novice teachers are often the most open minded about adopting curricular innovation because they are not yet deeply entrenched in existing practices. To take advantage of this high leverage point, a collaborative of space scientists and science educators at the University of California, Berkeley’s Lawrence Hall of Science and Center for Science Education at the Space Sciences Laboratory with experts from the Astronomical Society of the Pacific, the University of Wyoming, and the CAPER Center for Astronomy & Physics Education experimented with a unique professional development model focused on helping master teachers work closely with pre-service teachers during their student teaching internship field experience. The Advancing Mentor and Novice Teachers in Space Science (AMANTISS) team first identified master teachers who supervise novice, student teachers and trained these master teachers to use the GEMS Space Science Curriculum Sequence. Then, these master teachers were mentored in coaching interning student teachers assigned to them in using GEMS materials. Evaluation showed that novice teachers mentored by the master teachers felt knowledgeable after teaching the GEMS units. However, they seemed relatively less confident about the solar system and objects beyond the solar system. Overall, mentees felt strongly at the end of the year that they have acquired good strategies for teaching the various topics, suggesting that the support they received while teaching and working with a mentor was of real benefit to them. Funding provided in part by NASA ROSES AMANTISS NNX09AD51G

  4. Multiplexed barcoded CRISPR-Cas9 screening enabled by CombiGEM.

    Science.gov (United States)

    Wong, Alan S L; Choi, Gigi C G; Cui, Cheryl H; Pregernig, Gabriela; Milani, Pamela; Adam, Miriam; Perli, Samuel D; Kazer, Samuel W; Gaillard, Aleth; Hermann, Mario; Shalek, Alex K; Fraenkel, Ernest; Lu, Timothy K

    2016-03-01

    The orchestrated action of genes controls complex biological phenotypes, yet the systematic discovery of gene and drug combinations that modulate these phenotypes in human cells is labor intensive and challenging to scale. Here, we created a platform for the massively parallel screening of barcoded combinatorial gene perturbations in human cells and translated these hits into effective drug combinations. This technology leverages the simplicity of the CRISPR-Cas9 system for multiplexed targeting of specific genomic loci and the versatility of combinatorial genetics en masse (CombiGEM) to rapidly assemble barcoded combinatorial genetic libraries that can be tracked with high-throughput sequencing. We applied CombiGEM-CRISPR to create a library of 23,409 barcoded dual guide-RNA (gRNA) combinations and then perform a high-throughput pooled screen to identify gene pairs that inhibited ovarian cancer cell growth when they were targeted. We validated the growth-inhibiting effects of specific gene sets, including epigenetic regulators KDM4C/BRD4 and KDM6B/BRD4, via individual assays with CRISPR-Cas-based knockouts and RNA-interference-based knockdowns. We also tested small-molecule drug pairs directed against our pairwise hits and showed that they exerted synergistic antiproliferative effects against ovarian cancer cells. We envision that the CombiGEM-CRISPR platform will be applicable to a broad range of biological settings and will accelerate the systematic identification of genetic combinations and their translation into novel drug combinations that modulate complex human disease phenotypes.

  5. On the challenges of high resolution forecasting with the Global Environmental Multiscale (GEM) atmospheric model

    Science.gov (United States)

    Zahid Husain, Syed; Girard, Claude

    2016-04-01

    High resolution forecasting at the sub-kilometer scale with the Global Environmental Multiscale (GEM) atmospheric model leads to a number of challenges. The three-dimensional elliptic problem resulting from vertical discretization imposes severe restrictions on the vertical resolution and the time-step size in order to maintain vertical separability that permits the use of a direct solver. Although iterative solvers do not depend on vertical separability, readjusting the contributions of the nonhydrostatic pressure perturbation is found to circumvent the separability issue for the direct solver. In addition to the vertical-separability problem, at sub-kilometer resolutions the model currently exhibits strong instability particularly over complex orography where the model may encounter mountains with steep slopes. Off-centered averaging in the semi-Lagrangian scheme as well as the explicit high order numerical diffusion scheme - available within the GEM model to control high wave number noise - are found to be inadequate in addressing this strong orography-induced instability. Increasing the level of off-centering for the equations attributable to the non-hydrostatic aspects of the atmospheric flow is found to improve model stability during preliminary tests. Furthermore, as the existing hyperdiffusion schemes in GEM does not conserve angular momentum a new Smagorinsky-type diffusion scheme is currently being developed that will be compatible with the conservation laws. The improved diffusion scheme coupled with the modified off-centering of the non-hydrostatic equations is expected to have a more meaningful impact on the orgography-induced instability. Pertinent results will be presented at the conference.

  6. Typenbildung mit quantitativen und qualitativen Daten : methodologische Überlegungen

    OpenAIRE

    Promberger, Markus (Hrsg.)

    2011-01-01

    In diesem Essay wird gezeigt, dass die Verschränkung von qualitativen und quantitativen Methoden im Forschungsprozess nicht nur durch das Zählen von Wörtern in qualitativen Dokumenten, durch Exemplifikation von Statistiken mit Einzelfallstudien, durch 'hypothesengenerierende' Explorationsstudien oder ähnliches geschehen kann. Vielmehr stellt die Typenbildung einen Schlüsselschritt für die Genese konvergenter Befunde aus beiden methodischen Richtungen dar. Der Aufsatz skizziert eine wissenscha...

  7. Staatlicher Umgang mit sexuellem Mißbrauch

    OpenAIRE

    Oberloskamp, Helga

    1996-01-01

    Das Thema bedarf differenzierter Betrachtung, da sich "der Staat" in seinen drei Gewalten Legislative, Exekutive, Judikative darstellt. Die Exekutive wird vor allem durch das Jugendamt repräsentiert, dessen Aufgaben das KJHG differenziert benennt. Dagegen sagt das Gesetz wenig darüber aus, wie die Aufgaben zu erledigen sind. Allerdings ist eine Kooperation mit Freien Trägern der Jugendhilfe, dem Vormundschafts- und Familiengericht und anderen bezeichneten Stellen (z B Schule, Polizei) vorgesc...

  8. Modellierung und Verifikation von Eisenbahn-Infrastrukturen mit semantischen Technologien

    OpenAIRE

    Lodemann, Michael

    2014-01-01

    Diese Arbeit zeigt, wie semantische Technologien (Sprachen und Werkzeuge) genutzt werden können, um Eisenbahn-Infrastrukturen zu modellieren und zu verifizieren. Dazu wurde ein semantisches Domänen-Modell entworfen und implementiert, das sowohl die Elemente von Eisenbahn-Infrastrukturen und deren Eigenschaften als auch die Beziehungen dieser Elemente untereinander darstellen kann. Zur Modellierung wurde die Web Ontology Language (OWL) in Kombination mit der Semantic Web Rule Language (SWRL) v...

  9. Herstellung dotierter Nanodiamantpartikel und ihre Funktionalisierung mit schwefelhaltigen Gruppen

    OpenAIRE

    Heyer, Steffen

    2015-01-01

    In dieser Dissertation werden Methoden zur Darstellung von Stickstoff- und Bor-dotierten Nanodiamantpartikeln durch Vermahlung von makroskopischem HPHT- und CVD-Diamant mit unterschiedlichen Mühlen und Mahlverfahren beschrieben. Untersucht wird dabei der Zusammenhang von erzielten Teilchengrößen nach dem Mahlen und den Kristallitgrößen der Ausgangsdiamanten sowie der angewandten Mahlmethode. Durch Anwendung verschiedener oxidativer Methoden wird während des Mahlens entstehender sp2-Kohlenstof...

  10. Hochtemperaturverhalten von Stahlbetonplatten mit Textilbetonverstärkung

    OpenAIRE

    Hothan, Sascha; Ehlig, Daniel

    2011-01-01

    Die Verwendung von Endlosfilamenten aus Carbon als Bewehrungsmaterial für Beton, sogenannter Textilbeton, bietet die Möglichkeit der Sanierung und der Verstärkung bestehender Stahlbetonkonstruktionen. Dabei muss die Frage nach dem Feuerwiderstand von derart verstärkten Tragwerken beantwortet werden. Aufschluss darüber liefern Brandversuche. Mit Textilbeton verstärkte Stahlbetonplatten haben in Brandversuchen nach der Einheits- Temperaturzeitkurve bei 33 % der Traglast mehr als 60 Minuten stan...

  11. Aktivierung von Makrophagen durch Maillard-Produkte mit Aminoreduktonstruktur

    OpenAIRE

    Wühr, Andrea

    2010-01-01

    Durch Zubereitung oder Lagerung von Lebensmitteln, aber auch in vivo reagieren in der Maillard-Reaktion reduzierende Zucker mit Aminen, Aminosäuren oder Proteinen zu einer komplexen Mischung an Maillard-Produkten. Noch ungeklärt ist bislang in wie weit sich der Verzehr dieser Produkte positiv oder negativ auf die Gesundheit des Menschen auswirkt. Aufgrund vieler erwünschter sensorischer Eigenschaften dieser Produkte (braune Farbe, Geschmack und Aroma), werden bedeutende Mengen durch die Nahru...

  12. Funktionsdiagnostik von Inselzellen des Schweins mit einer miniaturisierten Mikroperifusionskammer

    OpenAIRE

    Schlosser, Stefan

    2007-01-01

    Die Forschung um die Optimierung der Insel-Transplantation nimmt in der Behandlung des Typ I Diabetes eine Vorreiterstellung ein. Nachdem im Zeitraum von drei Jahrzehnten Fortschritte im Bereich der Insel-Isolierung und Immunosuppression gemacht wurden, stehen wir heute am Beginn des klinischen Einsatzes dieser Technik an ausgewählten Patientengruppen. Ziel der vorliegenden Arbeit ist die umfassende Funktionsdiagnostik isolierter porziner mikroverkapselter Inseln. Mit Hilfe einer miniaturisie...

  13. Internationales Team Building aus britischer Perspektive: mit Schwerpunkt interkultureller Kompetenz

    OpenAIRE

    Bründl-Price, Sonja

    2004-01-01

    In Zeiten wachsender Globalisierung sind internationale Teams alltäglich und werden mit allen möglichen Schattierungen von Erfolg und Misserfolg konfrontiert. Menschen unterschiedlichen kulturellen Hintergrundes bemühen sich, einander zu verstehen, interkulturelle Hindernisse zu überwinden und Gruppenpotenziale zu optimieren. Oft erübrigt sich die Frage nach der Erfolgsrate internationaler Teams im Vergleich zu monokulturellen Gruppen, da Internationalität heutzutage wesentlicher Bestandteil ...

  14. MitBASE: a comprehensive and integrated mitochondrial DNA database

    OpenAIRE

    Antimonelli, M.; Altamura, N.; Benne, R.; Boyen, C; Brennicke, A; Carone, A; Cooper, J. M.; D'Elia, D.; Montalvo, de, A.; Pinto, de, B.; Robertis, De, M.; Golik, P.; Grienenberger, J M; Knoop, V.; Lanave, C.

    1999-01-01

    MitBASE is an integrated and comprehensive database of mitochondrial DNA data which collects all available information from different organisms and from intraspecie variants and mutants. Research institutions from different countries are involved, each in charge of developing, collecting and annotating data for the organisms they are specialised in. The design of the actual structure of the database and its implementation in a user-friendly format are the care of the European Bioinformatics I...

  15. Gruppendiskussionen mit Kindern : die dokumentarische Interpretation von Spielpraxis und Diskursorganisation

    OpenAIRE

    Nentwig-Gesemann, Iris

    2002-01-01

    "Im Interaktionsgeflecht der Gleichaltrigenkultur produzieren Kinder als soziale Akteure soziale Wirklichkeit und kulturelle Bedeutungen. Gruppendiskussionen und die dokumentarische Methode der Interpretation werden als geeignete Verfahren vorgestellt, mit denen im Rahmen der Kindheitsforschung neue Zugänge zur Perspektive der Kinder und ihren alltagskulturellen Praktiken eröffnet werden können. Über die Reflexion und Rekonstruktion forschungspraktischer Erfahrungen wird hier die schrittweise...

  16. Experimentelle und simulative Tropfenaufprallbestimmung mit einem piezoelektrischen Sensor

    OpenAIRE

    Bulur, Ertan; Mendig, Christian

    2015-01-01

    Im Rahmen des SuLaDi Projekts wird unter anderem an Eiserkennungskonzepten gearbeitet. Damit sich überhaupt ein Eisansatz bilden kann, muss auf der entsprechenden Fläche des Versuchskörpers Wasser vorhanden sein. Wasser gelangt unter realen Bedingungen, wie auch im Windkanalversuch tropfenweise auf den Versuchskörper und gefriert. Diese Arbeit beschäftigt sich mit der Problemstellung, ob der Aufprall eines Wassertropfens durch den Einsatz einer Piezofolie aus Polyvinylidenfluorid erkannt w...

  17. Formgedächtnis-Mikroventile mit hoher Energiedichte.

    OpenAIRE

    Liu, Yong; Kohl, Manfred

    2007-01-01

    Diese Arbeit beschreibt die Entwicklung von Formgedächtnis-Mikroventilen und daraus aufgebauter Durchflussregler für mikrofluidische Anwendungen. Ein erklärtes Ziel war die Bereitstellung einer hohen Energiedichte, um möglichst kompakte Bauelemente mit großem Arbeitsvermögen zu realisieren. Von den bekannten Energiewandlungsprinzipien zeigt der Formgedächtnis- (FG-) Effekt die höchste Energiedichte. Daher liegt der Schwerpunkt der Arbeit in der Entwicklung mikrosystemt...

  18. Vogelkundliche Fachliteratur und Internetquellen mit www.vifabio.de recherchieren

    OpenAIRE

    Dähne, Judith

    2010-01-01

    Die Virtuelle Fachbibliothek Biologie (www.vifabio.de) bündelt die Recherche nach wissenschaftlich hochwertigen Quellen aus Bibliotheken, Aufsatzbanken und Internet. Zentrales Element von vifabio ist dabei der Virtuelle Katalog: Mit einer Suchanfrage werden mehrere Kataloge zoologisch bzw. ornithologisch relevanter Bibliotheken, Zeitschriftendatenbanken wie Zoological Record (Nationallizenz 1864 bis 2007 für Nutzer in akademischen Einrichtungen), BioLIS und der Aufsatzkatalog OLC, sowie Lande...

  19. Resonanzionisations-Massenspektrometrie mit gepulsten und kontinuierlichen Lasern an Plutonium

    OpenAIRE

    Kunz, Peter

    2004-01-01

    Zusammenfassung Zur Weiterentwicklung derResonanzionisations-Massenspektrometrie (RIMS) für dieUltra-Spurenanalyse von Plutonium wurde im Rahmen dieserArbeit eine neue RIMS-Apparatur konzipiert und aufgebaut.Erstmals wurden bei der spektroskopischen Untersuchung vonPlutonium schmalbandige kontinuierliche Laser verwendet. Eswurdenumfangreiche Messreihen durchgeführt, um denResonanzionisationsprozess von Plutonium mit kontinuierlichenLasern zuspezifizieren und möglichst effiziente Anregungsl...

  20. Quark Orbital Angular Momentum in the MIT Bag Model

    OpenAIRE

    Burkardt, Matthias; Jarrah, Abdullah

    2010-01-01

    Using the MIT bag model, we study the contribution from the gluon vector potential due to the spectators to the orbital angular momentum of a quark in the bag model. For $\\alpha_s = {\\cal O}(1)$, this spectator contribution to the quark orbital angular momentum in the gauge-covariant Ji decomposition is of the same order as the non gauge-covariant quark orbital angular momentum and its magnitude is larger for $d$ than for $u$ quarks and negative for both.

  1. Hochauflösende Verarbeitung von Radardaten mit synthetischer Apertur

    OpenAIRE

    Mittermayer, Josef

    2000-01-01

    Diese Arbeit stellt das neuartige Frequenz-Skalierungs-Verfahren zur effizienten und genauen Verarbeitung von Spotlight-SAR-Daten ohne Interpolation vor. Es wird eine genaue Modellierung der Spotlight-Abbildungsgeometrie eingeführt. Eine neue analytische Formulierung für SAR-Rohdaten mit Dechirp on Receive-Operation wird abgeleitet. Aufbauend auf dieser Formulierung erfolgt die Entwicklung einer interpolationsfreien Korrektur der Zielentfernungsänderung, der sogenannten Frequenz-Skalierung. ...

  2. Leistungen an Familien mit Kindern im internationalen Vergleich

    OpenAIRE

    Clasen, Jochen

    1994-01-01

    'Ausgehend von einer Beschreibung von Zielsetzung und Methode werden wesentliche Ergebnisse einer empirisch vergleichenden Studie über familienpolitische Fördersysteme in den Mitgliedsländern der Europäischen Gemeinschaft, Norwegen, Australien und den USA vorgestellt. Im Zentrum des Projekts stehen die Darstellung der Struktur und die Bewertung von Maßnahmen, die Familien mit Kindern direkt und indirekt unterstützen ('child support packages'). Es wurde versucht, die monetären Entlastungseffek...

  3. CWSpace: Archiving MIT OpenCourseWare in DSpace

    OpenAIRE

    Reilly, William

    2005-01-01

    Charged with archiving all of MIT's OpenCourseWare content, the CWSpace project has been exploring new kinds of development on the Dspace platform in two key directions: packaging metadata and protocols. This talk reports on progress towards the support of new, standards-based ingest (and dissemination) functionality (e.g., IMS Content Packaging), as well as in the area of new "lightweight network interfaces" capabilities (e.g., Web Services protocols). Each of these development efforts is de...

  4. Mitä väliä on historialla?

    OpenAIRE

    Miettinen, Tiina; Toivo, Raisa (ed.) Maria

    2016-01-01

    Mitä väliä on historialla (“What good is history?”) is edited by Dr. Tiina Miettinen and Dr. Raisa Maria Toivo. Can history be useful and if so, what is it useful for? This book explores the impact of history and historical research. It gives a general introduction and various case studies – together with a piece of fiction – on how different parts of society can benefit, or have used, the study of history.

  5. Knochenablation mit fasergeführtem XeCl-Excimerlaserstrahl

    OpenAIRE

    Jahn, Renate; Dressel, Martin; Langendorff, Hans-Ulrich; Neu, Walter; Jungbluth, Karl-Heinz

    1991-01-01

    Eine neue Lasertechnik erweckt durch ihr "athermisches" Abtragungsprinzip nun auch das Interesse der Unfallchirurgen. Mit hoher Schnittqualität und präzisem Bohren bei industriellen Fertigungsverfahren zeigte der Excimerlaser andere Wege in der Oberflächenbearbeitung von Hartmaterialien (Glas, Keramik, Diamant) auf.Die Materialabtragung erfolgt nicht mehr durch ausschließlich photothermische Wirkung, sondern indem auch molekulare Bindungen aufgrund der hohen Photonenenergie des Lasers aufgebr...

  6. An Entrepreneurial Well-being Model based on GEM Data for Spain

    Directory of Open Access Journals (Sweden)

    José Manuel Sáiz-Álvarez

    2014-03-01

    Full Text Available The Economics of Happiness is one of the research areas of greatest growth in recent years. Throughout this work, a venture based model in which satisfaction of Spanish entrepreneurs with their professional life is performed. We analyze the responses of 9,989 entrepreneurs using data from the Global Entrepreneurship Monitor (GEM, and six hypothesis are discussed. The results show that, for the Spanish case, there is a strong consistency in the results the opportunity entrepreneurs present greater satisfaction than necessity entrepreneurs.

  7. Performance of a Large-area GEM Detector Read Out with Wide Radial Zigzag Strips

    OpenAIRE

    Zhang, Aiwu; Bhopatkar, Vallary; Hansen, Eric; Hohlmann, Marcus; Khanal, Shreeya; Phipps, Michael; Starling, Elizabeth; Twigger, Jessie; Walton, Kimberly

    2015-01-01

    A 1-meter-long trapezoidal Triple-GEM detector with wide readout strips was tested in hadron beams at the Fermilab Test Beam Facility in October 2013. The readout strips have a special zigzag geometry and run along the radial direction with an azimuthal pitch of 1.37 mrad to measure the azimuthal phi-coordinate of incident particles. The zigzag geometry of the readout reduces the required number of electronic channels by a factor of three compared to conventional straight readout strips while...

  8. An X-ray imaging device based on a GEM detector with delay-line readout

    Science.gov (United States)

    Zhou, Yi; Li, Cheng; Sun, Yong-Jie; Shao, Ming

    2010-01-01

    An X-ray imaging device based on a triple-GEM (Gas Electron Multiplier) detector, a fast delay-line circuit with 700 MHz cut-off frequency and two dimensional readout strips with 150 μm width on the top and 250 μm width on the bottom, is designed and tested. The localization information is derived from the propagation time of the induced signals on the readout strips. This device has a good spatial resolution of 150 μm and works stably at an intensity of 105 Hz/mm2 with 8 keV X-rays.

  9. Developments of a large area VUV sensitive gas PMT with GEM/μPIC

    International Nuclear Information System (INIS)

    A new large area UV photon detector with micro pattern gaseous detectors is developed and evaluated. A semitransparent CsI photocathode deposited on a MgF2 window was combined with 10cm x 10cm GEM and μPIC. Using Ar+C2H6 (10%) gas, we achieved the gas gain of more than 105 which is enough to detect single photoelectron. We, then, irradiated vacuum UV photons (VUV, around 172nm) from the newly developed LaF3(Nd) scintillator to the detector and the single photoelectrons were successfully detected. We also demonstrated the imaging capability of the detector with μPIC readout systems.

  10. 独具一格的Dynavox GEM Opal音箱

    Institute of Scientific and Technical Information of China (English)

    云断峰

    2003-01-01

    @@ 说到音箱,相信绝大部分读者都会想到那个四四方方的矩形箱体.的确,市面绝大多数音箱就是给我们留下这样的印象,音箱还有不同于矩形的设计吗?当然有,在这里笔者就为读者介绍一款来自德国的两分频中型座地箱Dynavox GEM Opal.

  11. Gem1 and ERMES Do Not Directly Affect Phosphatidylserine Transport from ER to Mitochondria or Mitochondrial Inheritance

    DEFF Research Database (Denmark)

    Nguyen, Tammy T; Lewandowska, Agnieszka; Choi, Jae-Yeon;

    2012-01-01

    In yeast, a protein complex termed the ER-Mitochondria Encounter Structure (ERMES) tethers mitochondria to the endoplasmic reticulum. ERMES proteins are implicated in a variety of cellular functions including phospholipid synthesis, mitochondrial protein import, mitochondrial attachment to actin......, polarized mitochondrial movement into daughter cells during division, and maintenance of mitochondrial DNA (mtDNA). The mitochondrial-anchored Gem1 GTPase has been proposed to regulate ERMES functions. Here, we show that ERMES and Gem1 have no direct role in the transport of phosphatidylserine (PS) from...... the ER to mitochondria during the synthesis of phosphatidylethanolamine (PE), as PS to PE conversion is not affected in ERMES or gem1 mutants. In addition, we report that mitochondrial inheritance defects in ERMES mutants are a secondary consequence of mitochondrial morphology defects, arguing against...

  12. Gillespie eco-evolutionary models (GEMs) reveal the role of heritable trait variation in eco-evolutionary dynamics.

    Science.gov (United States)

    DeLong, John P; Gibert, Jean P

    2016-02-01

    Heritable trait variation is a central and necessary ingredient of evolution. Trait variation also directly affects ecological processes, generating a clear link between evolutionary and ecological dynamics. Despite the changes in variation that occur through selection, drift, mutation, and recombination, current eco-evolutionary models usually fail to track how variation changes through time. Moreover, eco-evolutionary models assume fitness functions for each trait and each ecological context, which often do not have empirical validation. We introduce a new type of model, Gillespie eco-evolutionary models (GEMs), that resolves these concerns by tracking distributions of traits through time as eco-evolutionary dynamics progress. This is done by allowing change to be driven by the direct fitness consequences of model parameters within the context of the underlying ecological model, without having to assume a particular fitness function. GEMs work by adding a trait distribution component to the standard Gillespie algorithm - an approach that models stochastic systems in nature that are typically approximated through ordinary differential equations. We illustrate GEMs with the Rosenzweig-MacArthur consumer-resource model. We show not only how heritable trait variation fuels trait evolution and influences eco-evolutionary dynamics, but also how the erosion of variation through time may hinder eco-evolutionary dynamics in the long run. GEMs can be developed for any parameter in any ordinary differential equation model and, furthermore, can enable modeling of multiple interacting traits at the same time. We expect GEMs will open the door to a new direction in eco-evolutionary and evolutionary modeling by removing long-standing modeling barriers, simplifying the link between traits, fitness, and dynamics, and expanding eco-evolutionary treatment of a greater diversity of ecological interactions. These factors make GEMs much more than a modeling advance, but an important

  13. Resolution dependence in simulating the African hydroclimate with the HadGEM3-RA regional climate model

    Science.gov (United States)

    Moufouma-Okia, W.; Jones, R.

    2015-02-01

    This study documents the effect of horizontal resolution on the ability of the Met Office third-generation Global Atmosphere Regional Climate Model (HadGEM3-RA), a regional atmospheric configuration of the HadGEM3 model, to simulate rainfall variability over Africa. It is based on six 20-year long RCM simulations driven by ERA-Interim reanalysis and performed at 12, 25, 50, 70, 90, and 150 km over the CORDEX-Africa domain. To gain further insight into model errors, we also compared the HadGEM3-RA's performance to that of the parent General Circulation Model using three different spatial resolutions (70, 100, and 150 km), and to HadRM3P—the current Met Office regional climate model. It is found that the 50 km resolution RCM reproduces reasonably the spatial and temporal features of rainfall variability across regions. These include the seasonal progression of the tropical rainbelt, its extent and location, the annual cycle and interannual variability. Although model biases vary across seasons and locations, a prominent feature is the over-prediction of rainfall totals over Central Africa, and underestimation of rainfall in coastal areas of the Guinea Gulf during boreal spring and autumn. HadGEM3-RA improves with increased horizontal resolution, but some model errors persist. Comparison with the parent global model simulations demonstrates generally a realistic and consistent behaviour over large scales—suggesting that the physical formulation is able to capture the key driving processes, but also confirms the benefit of increasing the model horizontal resolution. Despite the model errors, HadGEM3-RA rainfall shows superiority over that from HadRM3P, ERA-Interim and MERRA datasets—indicating that the associated dynamical features of HadGEM3-RA can complement the physical understanding gained from reanalyses. This article also highlights the challenges for evaluating climate models in data sparse regions where satellite derived rainfall and gridded observational

  14. Atmospheric gaseous elemental mercury (GEM concentrations and mercury depositions at a high-altitude mountain peak in south China

    Directory of Open Access Journals (Sweden)

    X. W. Fu

    2010-03-01

    Full Text Available China is regarded as the largest contributor of mercury (Hg to the global atmospheric Hg budget. However, concentration levels and depositions of atmospheric Hg in China are poorly known. Continuous measurements of atmospheric gaseous elemental mercury (GEM were carried out from May 2008 to May 2009 at the summit of Mt. Leigong in south China. Simultaneously, deposition fluxes of THg and MeHg in precipitation, throughfall and litterfall were also studied. Atmospheric GEM concentrations averaged 2.80±1.51 ng m−3, which was highly elevated compared to global background values but much lower than semi-rural and industrial/urban areas in China. Sources identification indicates that both regional industrial emissions and long range transport of Hg from central, south and southwest China were corresponded to the elevated GEM level. Seasonal and diurnal variations of GEM were observed, which reflected variations in source intensity, deposition processes and meteorological factors. Precipitation and throughfall deposition fluxes of THg and MeHg in Mt. Leigong were comparable or lower compared to those reported in Europe and North America, whereas litterfall deposition fluxes of THg and MeHg were higher compared to Europe and North America. This highlights the importance of vegetation to Hg atmospheric cycling. In th remote forest ecosystem of China, deposition of GEM via uptake of foliage followed by litterfall was very important for the depletion of atmospheric Hg. Elevated GEM level in ambient air may accelerate the foliar uptake of Hg through air which may partly explain the elevated litterfall deposition fluxes of Hg observed in Mt. Leigong.

  15. First demonstration of VUV-photon detection in liquid xenon with THGEM and GEM-based Liquid Hole Multipliers

    CERN Document Server

    Erdal, E; Rappaport, M; Shchemelinin, S; Vartsky, D; Breskin, A

    2016-01-01

    The bubble-assisted Liquid Hole-Multiplier (LHM) is a recently-introduced detection concept for noble-liquid time projection chambers. In this "local dual-phase" detection element, a gas bubble is supported underneath a perforated electrode (e.g., Thick Gas Electron Multiplier - THGEM, or Gas Electron Multiplier - GEM). Electrons drifting through the holes induce large electroluminescence signals as they pass into the bubble. In this work we report on recent results of THGEM and GEM electrodes coated with cesium iodide and immersed in liquid xenon, allowing - for the first time - the detection of primary VUV scintillation photons in addition to ionization electrons using LHMs.

  16. Design of a Constant Fraction Discriminator for the VFAT3 front-end ASIC of the CMS GEM detector

    CERN Document Server

    Loddo, Flavio

    2015-01-01

    In this work the design of a Constant Fraction Discriminator (CFD) to be used in the VFAT3 chip, currently under design for the read-out of the Triple-Gem detectors of the CMS experiment, is described. Simulations show that it is possible to extend the front-end shaping time in order to fully integrate the GEM detector signal charge whilst maintaining optimal timing resolution using the CFD technique. A prototype chip containing 8 CFDs was implemented in 130 nm CMOS technology to prove the effectiveness of the proposed architecture before its integration in the VFAT3 chip. The CFD design and test results will be shown.

  17. Trace elemental analysis of Indian natural moonstone gems by PIXE and XRD techniques.

    Science.gov (United States)

    Venkateswara Rao, R; Venkateswarulu, P; Kasipathi, C; Sivajyothi, S

    2013-12-01

    A selected number of Indian Eastern Ghats natural moonstone gems were studied with a powerful nuclear analytical and non-destructive Proton Induced X-ray Emission (PIXE) technique. Thirteen elements, including V, Co, Ni, Zn, Ga, Ba and Pb, were identified in these moonstones and may be useful in interpreting the various geochemical conditions and the probable cause of their inceptions in the moonstone gemstone matrix. Furthermore, preliminary XRD studies of different moonstone patterns were performed. The PIXE technique is a powerful method for quickly determining the elemental concentration of a substance. A 3MeV proton beam was employed to excite the samples. The chemical constituents of moonstones from parts of the Eastern Ghats geological formations of Andhra Pradesh, India were determined, and gemological studies were performed on those gems. The crystal structure and the lattice parameters of the moonstones were estimated using X-Ray Diffraction studies, trace and minor elements were determined using the PIXE technique, and major compositional elements were confirmed by XRD. In the present work, the usefulness and versatility of the PIXE technique for research in geo-scientific methodology is established.

  18. BVRI Photometry of nz Gem, HD 73017, HD 77247, RT Vir and 104 Her

    Science.gov (United States)

    Adelman, Saul J.; Harrell, William L.

    We examined single channel differential BVRI photometry of the cool stars NZ Gem, HD 73017, HD 77247, RT Vir and 104 Her obtained by the first author with the Four College Automated Photoelectric Telescope with of order 100 observations taken over two or more years. Four of these stars are Small-Amplitude Red Variables (SARVs). The primary period of NZ Gem (M3 II-IIIs) is about 33.70 days. HD 77247, the shortest period barium star with spectral type K0, has a photometric period of about 82 days which is close to its binary period of 80.53 days. Its check star HD 73017, a non-variable in B, V and R, is variable in I due most likely to a previously unknown cooler companion. RT Vir (M8 III) is found to be a multiperiodic star whose observations are consistent with the 155 day primary period of Lebzelter & Hinkle (2002). 104 Her (M3 III) is also multiperiodic with a primary period of 21.48 days.

  19. Gem of an idea: ITT to study high resolution remote sensing data

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2000-12-01

    The Geological and Environmental Mapping (GEM) of Image Interpretation Technologies Inc (ITT) is a new technology in exploration and environmental mapping. The GEM project is supported by the Canadian Space Agency to evaluate the ability of high-resolution remote sensing to support the needs of the oil industry in exploration, environmental monitoring, seismic and pipeline design. The project aims to establish a knowledge base regarding surface oil detection using airborne hyperspectral data prior to launch of equivalent satellite platforms. Since the presence of surface oil deposits is often indicative of local migration pathways, it can be used to pinpoint reserves by correlating them with sub-surface data such as high resolution magnetics or seismic. ITT, in addition to a 25 square kilometre hyperspectral shoot over the Norman Wells study area, also acquired and compiled regional seismic data, high-resolution satellite imagery and geological data from the same area. It is expected that the project will demonstrate the hyperspectral signature of oil seeps and spills, the capabilities of hyperspectral data to map exposed geological units, and to demonstrate the use of integrated products for pipeline planning and emergency and disaster response planning. 2 figs.

  20. TPC-like readout for thermal neutron detection using a GEM-detector

    Science.gov (United States)

    Flierl, B.; Hertenberger, R.; Biebel, O.; Zeitelhack, K.

    2016-07-01

    Spatial resolution of less than 200 μm is challenging for thermal neutron detection. A novel readout scheme based on the time-projection-chamber (TPC) concept is used in a gaseous electron multiplier (GEM) detector [1]. Thermal neutrons are captured in a single 2 μm thick Boron-10 converter cathode and secondary Helium and Lithium ions are produced with a combined energy of 2.8 MeV. These ions have sufficient energy to form straight tracks of several mm length. With a time resolving 2-dimensional readout of 400 μm pitch in both directions, based on APV25 chips, the ions are tracked and their respective origin in the cathode converter foil is reconstructed. Using an Ar-CO2 93:7% gas mixture, a resolution of 100 μm (FWHM 235 μm) has been observed with a triple GEM-detector setup at the Garching neutron source (FRMII) for neutrons of 4.7 Å.

  1. Characterization of a glass GEM for sealed detectors application and reduction of charging-up effects

    CERN Document Server

    Erdal, Eran

    2014-01-01

    Apart from high energy physics experiments, there has been a great effort in recent years to incorporate MPGDs in many other applications i.e. medical treatments and imaging and home land security. However, MPGDs (as most gaseous detectors) are normally operated under a constant flushing of the gas. Their use thus turns them expensive since they rely on a constant gas supply and a suitable infrastructure, but most important is the loss of their portability. These reasons have pushed the community to search for other solutions, aiming for the development of sealed detectors. The demands for such is to be made out of low outgassing rate materials and possibly the use of only noble gas to avoid aging due to chemical activity of the ionized gas of the avalanche. The default material for GEM detectors - Polyimide (Kapton), is not suitable for a sealed detector because of its high outgassing rate, thus calling for new solutions. Moreover, GEMs, being essentially made out of an insulating material, pose a problem in...

  2. Morbidity Profile of Child Labor at Gem Polishing Units of Jaipur, India

    Directory of Open Access Journals (Sweden)

    RR Tiwari

    2014-07-01

    Full Text Available Background: There are millions of working children worldwide. Several causes are suggested for this social evil of which poverty plays a significant role in whether a child will work.Objective: To determine the morbidity profile in the working children of gem polishing units of Jaipur, India and assess some of its associated socio-economic factors.Methods: The present cross-sectional study included 586 gem polishing working children. Using interview, the demographic characteristics, occupational and clinical history of participants were recorded. The reason for taking up the job, income from the job and their desire to attend the school were also asked to assess the social causes of child labor in this region.Results: The mean±SD age of the working children was 11.3±5.3 years. In most of the instances, parents compelled the child to take up the job. Supposed to increase the family income substantially, the child labor activity failed to do so. On the other hand, the children suffered from several occupational health problems like eyestrain, headache, gastrointestinal complaints (eg, abdominal pain, nausea, vomiting, and diarrhea, musculoskeletal symptoms (eg, back pain, pain in limbs, neck pain, and joint pains and skin diseases (eg, scabies, dermatitis.Conclusion: It seems that the social factors forcing the children to work in the studied region, result in deterioration of their health and affect their growth.

  3. Prototype sector magnets for the GeV electron microtron (GEM)

    International Nuclear Information System (INIS)

    Three prototypes of the sector magnets for GeV Electon Microtron accelerators have been designed. One has been built and two are being constructed. The first is a full scale, 168 ton prototype for one-half of a 2 GeV Double Sided Microtron (DSM) sector magnet. The successful fabrication and testing of the pole pieces for this prototype has demonstrated that their required close tolerances for flatness and parallelism can be met. The second magnet is an approximate two-thirds scale model of one step at the low energy end of the hexatron sector magnet designed for the 4 GeV Electron Microtron (GEM). The measured fields demonstrate that the field falls off faster than an Enge-short-tail and error fields are at low levels and are controllable. A third prototype magnet exactly duplicates the full scale geometry of the first three full orbits of the GEM sector magnet from entrance to exit points. It will permit high precision measurements and corrections of field errors and verify the 3-D computer program, TOSCA

  4. Fast triggering of high-rate charged particles with a triple-GEM detector

    CERN Document Server

    Alfonsi, M; Bonivento, W; Cardini, A; De Simone, P; Murtas, F; Pinci, D; Poli-Lener, M; Raspino, D

    2004-01-01

    A 3 year long R&D activity on triple gas electron multiplier (GEM) detectors is reported. This activity was made in the framework of the LHCb experiment in order to find the technology to instrument the central region of the first muon station (M1R1) where a high particle rate is expected. Detector geometry, gas mixture and electric field configuration have been optimized in order to achieve the performance required by the experiment. The use of a very fast, CF//4 based, gas mixture provides a time resolution of about 4.5 ns (r.m.s.) with a single chamber with gain less than 10**4. In addition, an optimized gain sharing between the three GEMs allows to keep the discharge probability per incident hadron below $10^{-12}$. The average number of firing pads per crossing particle have been found to be lower than 1.2. In a global aging test two detectors were exposed to a dose rate of 16 Gy/h. Each detector integrated about 2 C/cm**2 equivalent to more than 10 years of operation at LHCb. Good aging properties w...

  5. Reading a GEM with a VLSI pixel ASIC used as a direct charge collecting anode

    CERN Document Server

    Bellazzini, R; Baldini, L; Bitti, F; Brez, A; Latronico, L; Massai, M M; Minuti, M; Omodei, N; Razzano, M; Sgro, C; Spandre, G; Costa, E; Soffitta, P

    2004-01-01

    In MicroPattern Gas Detectors (MPGD) when the pixel size is below 100 micron and the number of pixels is large (above 1000) it is virtually impossible to use the conventional PCB read-out approach to bring the signal charge from the individual pixel to the external electronics chain. For this reason a custom CMOS array of 2101 active pixels with 80 micron pitch, directly used as the charge collecting anode of a GEM amplifying structure, has been developed and built. Each charge collecting pad, hexagonally shaped, realized using the top metal layer of a deep submicron VLSI technology is individually connected to a full electronics chain (pre-amplifier, shaping-amplifier, sample and hold, multiplexer) which is built immediately below it by using the remaining five active layers. The GEM and the drift electrode window are assembled directly over the chip so the ASIC itself becomes the pixelized anode of a MicroPattern Gas Detector. With this approach, for the first time, gas detectors have reached the level of i...

  6. Development of entrepreneurship in Brazil based on indicators of the global entrepreneurship monitor (GEM

    Directory of Open Access Journals (Sweden)

    Ana Carolina Cozza Josende da Silva

    2015-06-01

    Full Text Available Entrepreneurship is very important in a society due to its influence with the growth and development of a country. The importance of studying and knowing the entrepreneurial activity and the entrepreneur's profile contributes positively to identify estimates of this activity and to clarify the future of this process. In this sense, this article presents the evolution of entrepreneurship in Brazil over the past 13 years, using for the study secondary data obtained from the GEM and IBGE researches, in which the search was conducted in documentary basis from 2001 to 2013. The results present a descriptive analysis of the Global Entrepreneurship Monitor entrepreneurship indicators (GEM concerning to the new entrepreneur rate and the rate of nascent entrepreneurs, growth of the Brazilian GDP related to entrepreneurship, entrepreneurship rate according to the entrepreneur stages (initial and established, initial entrepreneurs according to their motivation (by chance and necessity, by gender entrepreneurs, age, level of education. It was also carried out statistical analysis where the trend of the variables over time was verified by simple linear regression at the significance level of 5%. The study concludes that Brazil tends to present significant growth towards entrepreneurship, an advancement of the female contribution to the economy, increase of entrepreneurs because of more opportunities and stability in the existing businesses.

  7. Optimal spectral resolution for NO2 and SO2 retrieval by Geostationary Environmental Monitoring Spectrometer (GEMS)

    Science.gov (United States)

    Chong, J.; Kim, Y. J.; Scientific Team of DOAS

    2011-12-01

    Ministry of Environment, Korea is planning an environmental geostationary satellite program as a part of MP-GEOSAT (Multi-Purpose GEOstationary SATellite), which is scheduled to be launched in 2017 (Lee S. et al., 2010). It is supposed to be placed on an orbit of approximately 36,000 kilometers high directly over the equator, which revolves in the same direction the earth rotates. Its missions include meteorological, ocean monitoring, and environmental monitoring. Especially, Geostationary Environmental Monitoring Spectrometer (GEMS) is to provide atmospheric chemistry measurements of trace gases such as O3, NO2, SO2, HCHO, and aerosol in high temporal (every 1 hour) and spatial (30x30 km2) resolution over Asia, to monitor regional transport events such as transboundary pollution and Asian dust, and to enhance our understanding on interactions between atmospheric chemistry and meteorology. In order to determine the minimum required spectral resolution of GEMS, measurement accuracy has been estimated for different spectral resolutions based on the actual satellite data as well as model simulation data of very fine spectral resolution. Absorption spectra of SCIAMACHY level 2 data (http://www.temis.nl) with spectral resolution of 0.2nm and reconstructed spectra of broader spectral resolution; 0.4, 0.6, and 0.8nm have been utilized to assess the applicability for SO2 and NO2 retrievals over GEMS spatial coverage areas using the DOAS fitting method. The relative fitting error in SO2 retrieval of each spectral resolution over southern China was determined to be 45.1, 56.1, 99.7, and 187.3 %, respectively. The relative fitting errors in NO2 retrieval of each spectral resolution over northern India were 16.2, 24.6, 32.6, and 38.9 %, respectively. Since relative fitting error in SO2 retrieval increases as the spectra resolution increases, the optimal spectrum resolution was determined to be 0.4nm. On the other hand, since the relative fitting error in NO2 retrieval is below

  8. MAC GEMS

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Lion系统新添加的功能令人耳目一新,用户界面也有了很大的改动.然而有些用户却并不习惯Lion带来的新界面。好在通过系统偏好设置、终端或者第三方插件,就能很容易改Lion的界面。LionWeaks是一款简单的插件.它在一个独立窗口中提供了许多Lion版本的修改项,允许用户通过点击按钮更改某些设置。

  9. Favourite Gems

    Science.gov (United States)

    Barnes, John

    2011-01-01

    Mathematics is full of surprises and beauty. In this article, the author discusses three favourite topics that he finds both amazing and amusing: (1) the problem of the possibility of subdividing a rectangle into a number of different squares; (2) the arrangement formed when several soap bubbles meet; and (3) circles and spheres.

  10. Analyse der postoperativen Versorgung von Patienten mit proximaler Femurfraktur in einer Rehabilitationsklinik

    OpenAIRE

    Dreßler, Simone Anneliese

    2009-01-01

    Osteoporotische Frakturen sind im Zusammenhang mit proximalen Femurfrakturen beim älteren Menschen von hoher klinischer und sozioökonomischer Bedeutung. Trotz des weltweiten exponentiellen Anstiegs osteoporotischer Fakturen findet vor allem in den primär versorgenden Kliniken eine Identifizierung und adäquate Behandlung von Patienten mit hohem Risiko nur unzureichend statt. Es besteht eine hohe Variabilität innerhalb der Versorgung osteoporotischer Patienten mit PFF in der Rehabilitationsklin...

  11. Auslegung und Optimierung von Flanschverbindungen mit SMC-Losflanschen und PTFE-Dichtungen

    OpenAIRE

    Kurz, Hariolf

    2014-01-01

    Die Anforderungen an Rohrleitungen aus glasfaserverstärktem Kunststoff (GFK) sind im Hinblick auf die Dichtheit, die Medienbeständigkeit und die Betriebssicherheit in den letzten Jahren gestiegen. Dennoch müssen die Betreiber chemischer Anlagen mit Rohrleitungen aus glasfaserverstärktem Kunststoff mit Losflanschen aus sheet-molding-compound (SMC) diese nachweislich sicher betreiben. Die Motivation zu dieser Arbeit liegt darin, dieses Bestreben mit der Auswahl von geeigneten PTFE-Dichtungen un...

  12. Regelung von Robotern mit elastischen Gelenken am Beispiel der DLR-Leichtbauarme

    OpenAIRE

    Albu-Schäffer, Alin

    2007-01-01

    In der Arbeit werden Methoden zur Parameteridentifikation und Regelung von Robotern mit elastischen Gelenken vorgeschlagen, am Beispiel der DLR-Leichtbauroboter experimentell implementiert und im Dauereinsatz validiert. Das Modell des Manipulators mit elastischen Gelenken trifft sowohl für schnell bewegte Industrieroboter, wie auch für extrem leichte Roboter im Service- oder Raumfahrtbereich zu. Ausgehend von einem Gelenk-Zustandsregler mit konstanten Parametern und Kompensation der Starrkörp...

  13. Untersuchung von Verbesserungspotentialen hinsichtlich Verbrauch und Drehmoment bei Ottomotoren mit Hilfe 1-dimensionaler Simulationsrechnung

    OpenAIRE

    Schreiber, Gert

    2006-01-01

    Im Rahmen dieser Arbeit wurden verschiedene Verbesserungspotentiale von Ottomotoren mit besonderer Berücksichtigung von Verbrauch und Drehmoment mit Hilfe der Motorprozeßrechnung untersucht. Insbesondere wurden die Zusammenhänge von Ursache und Wirkung einzelner Verbesserungsmaßnahmen herausgestellt. Zur Modellierung realer Motoren wurde die Simulationssoftware GT-Power verwendet, wobei die Regelung über Matlab/Simulink vorgenommen wurde. Aber auch mit vereinfachten Rechenmodellen, die unter ...

  14. Quantitative Datenanalyse: Arbeiten mit SPSS Statistics : Eine Einführung

    OpenAIRE

    Hoidn, Sabine

    2012-01-01

    Bei diesem Buch handelt es sich um eine verständliche Einführung in das Arbeiten mit dem quantitativen Datenanalyseprogramm SPSS Statistics. Die Studierenden setzen sich mit den Grundlagen zum Arbeiten mit SPSS Statistics auseinander, können selbständig eine SPSS Statistics-Datei erstellen, Daten einlesen, zusammenfügen und modifizieren, erfasste Daten managen und die gebräuchlichsten tabellarischen und grafischen Grundauswertungen sowie Analyseverfahren durchführen und interpretieren. Au...

  15. The MIT TEAL Simulations and Visualizations in Electromagnetism

    Science.gov (United States)

    Belcher, John

    2007-03-01

    The Technology Enabled Active Learning (TEAL) Project at MIT has developed a broad range of 3D visualizations and simulations to foster student intuition about electromagnetic fields and phenomena (see http://web.mit.edu/8.02t/www/802TEAL3D/). In this talk we discuss the software approaches we use to create these simulations, including Macromedia Shockwave and Java 3D applets for interactive visualization, passive animations created with 3ds max, and the Dynamic Line Integral Convolution (DLIC) method for constructing time dependent representations of the electromagnetic field at close to the resolution of the computer display (Sundquist, 2003). The DLIC method, in particular, is far superior in delineating the spatial and temporal structure of fields as compared to e.g. field line displays or vector field grids. We also report on the use of these visualizations in instruction at the freshmen level. Our strong opinion is that for effective student learning, such visualizations must be embedded in a software framework for their interactive delivery. This ``guided inquiry'' framework is essential to influence and optimize what students take away from the visualizations. In our current research, we are delivering our visualizations using a commercial package, Addison Wesley's MasteringPhysics (MP), although any guided inquiry delivery system such as MP will be able to interact with our simulation software. We have released our Java 3D simulation software as open source with a liberal open source license (see http://jlearn.mit.edu/tealsim/ ), with support from the Davis Educational Foundation.

  16. Vergleich der Narbenausprägung und Bewertung der Kosmetik bei Patientinnen mit brusterhaltend operiertem Mammakarzinom und einseitiger Strahlenbehandlung nach simultaner Reduktionsmastektomie beidseits

    OpenAIRE

    Gatti, Alessia

    2014-01-01

    Mit der hier vorgelegten Arbeit sollte im Hinblick auf die Narbenbildung der Einfluss der alleinigen Operation verglichen werden mit dem Effekt einer Operation plus adjuvanter Strahlentherapie. Dazu wurde ein Patientinnenkollektiv mit bilateraler Operation, aber unilateraler Strahlenbehandlung ausgewählt. Diese Bedingungen sind bei Patientinnen mit unilateralem Mammakarzinom und gleichzeitiger beidseitiger Reduktionsmastektomie gegeben. Mit der beidseitigen Reduktionsmastektomie wird auf der ...

  17. The MIT – Cornell Collision and Why It Happened

    OpenAIRE

    Fletcher, Luke Sebastian; Teller, Seth; Olson, Edwin B.; Moore, David C.; Kuwata, Yoshiaki; How, Jonathan P.; Leonard, John Joseph; Miller, Isaac; Campbell, Mark; Huttenlocher, Dan; Nathan, Aaron; Kline, Frank-Robert

    2009-01-01

    Mid-way through the 2007 DARPA Urban Challenge, MIT’s autonomous Land Rover LR3 ‘Talos’ and Team Cornell’s autonomous Chevrolet Tahoe ‘Skynet’ collided in a low-speed accident, one of the first well-documented collisions between two full-size autonomous vehicles. This collaborative study between MIT and Cornell examines the root causes of the collision, which are identified in both teams’ system designs. Systems-level descriptions of both autonomous vehicles are given, and a...

  18. A Single Channel Measurement Svstem For Brain MIT

    Institute of Scientific and Technical Information of China (English)

    QINMing-xing; JIAOLi-cheng; WANGCong; LIShi-jun; DONGXiu-zhen; LUHua

    2004-01-01

    A single channel measurement system for brain MIT has been built. The system is composed of an exciting source unit, a detecting unit, a rotating and controlling unit, and imaging unit. The experiment results of single channel measurements show that the system output versus the conductivity of the objects was an approximate linear relationship when the diameter of an object was about 9cm and its conductivity was in 0.1 S/m, 0.7 S/m, 2S/m, 6S/m. The sensitivit yof the phase detector was 53 mV/degree from -10 to+10 degree.

  19. Innovative facades with photovoltaics; Innovative Fassaden mit Photovoltaik

    Energy Technology Data Exchange (ETDEWEB)

    Eicker, U. [Hochschule fuer Technik, Stuttgart (Germany)

    1999-10-01

    Having grown at a rate of 15% since the middle of the 1980s the photovoltaic market today commands an annual module production of more than 100 MW{sub p}. In Germany altogether 10,000 PV systems with a total power output of 10 MW{sub p} were newly installed in 1997 alone. In 1990 the market was boosted by the heavily subsidised 1000 roofs programme, under which in the end more than 2,000 systems were installed on the roofs of mostly one-family houses. With power ratings ranging from 1 to 5 kW these decentral plants require roof surface areas between 10 and 50 m-2. On average they generate 800 kWh of electricity per kW of installed power. According to a number of studies carried out in the early 1990s the total surface area on buildings available for photovoltaics amounts to an enormous potential of 1,000 km-2, which is equivalent to an electricity generating potential of 130 TWh (100 TWh on roofs and 30 TWh on facades), or 25% of Germany`s total electricity demand. The degree to which this potential will be realised in the long term will notably depend on whether convincing architectural solutions are found for integrating photovoltaic plants in roofs and facades. [Deutsch] Der Photovoltaikmarkt waechst weltweit seit Mitte der 80er Jahre um durchschnittlich 15% und liegt heute bei einer Jahresmodulproduktion ueber 100 MW{sub p}. In Deutschland wurden alleine 1997 etwa 10.000 PV-Systeme mit einer Gesamtleistung von 10 MW{sub p} installiert. Die Marktentwicklung wurde 1990 mit dem stark subventionierten 1000-Daecher Programm angestossen, in welchem schliesslich mehr als 2000 Systeme meist auf Daechern von Einfamilienhaeusern installiert wurden. Diese dezentralen Anlagen mit Leistungen zwischen 1 und 5 kW erfordern Dachflaechen zwischen 10 und 50 m{sup 2} und erzeugen im Schnitt 800 kWh Strom pro kW installierter Leistung. Das verfuegbare Flaechenpotential von Gebaeuden wurde Anfang der 90er Jahre in einer Reihe von Studien ermittelt und stellt mit etwa 1000 km{sup 2

  20. Sicheres Navigieren in dynamischen Umgebungen mit 3D-Kollisionsvermeidung

    Science.gov (United States)

    Stiene, Stefan; Hertzberg, Joachim

    Diese Papier stellt eine neuartige Methode vor, die 3D-Hindernisvermeidung ermöglicht. Die Sensorkonfiguration beruht auf sechs Laserscannern, die die gesamte Roboteroberfläche abdecken. Die Daten der sechs Laserscanner werden zu einem virtuellen, zweidimensionalen, horizontal ausgerichteten 360°-Laserscanner kombiniert. Da der virtuelle Laserscanner die 3D-Umgebung in einem zweidimensionalen Datensatz repräsentiert, ermöglicht er in Kombination mit klassischen Hindernisvermeidungsalgorithmen wie der Vector Field Histogram Methode eine 3D-Hindernisvermeidung.

  1. Mit Mathematik zu Mehr Intelligenz in der Logistik

    Science.gov (United States)

    Möhring, Rolf H.; Schenk, Michael

    Die Lösung logistischer Probleme ist ein wichtiger Aspekt menschlichen Handelns seit Menschen gemeinsam zielgerichtet tätig wurden. Die Grundlagen dessen, was wir heute Logistik nennen, entstammen dem militärischen Bereich. So basierte z. B. das römische Imperium in starkem Maße auf militärisch-logistischen Glanzleistungen. Ob damals bereits mathematische Überlegungen eine Rolle spielten, wissen wir heute nicht. Jedoch versuchte z. B. Napoleon, der mit den bedeutendsten Mathematikern seiner Zeit befreundet war, den Transport seiner Truppen und die Verbreitung von Informationen zu optimieren und strategisch einzusetzen.1,2

  2. Befunde und Therapie bei 461 Kühen mit Blinddarmdilatation

    OpenAIRE

    Beckmann, C

    2011-01-01

    In der vorliegenden Dissertation werden die klinischen Befunde, die Laborbe-funde, die Therapie und der Krankheitsverlauf von 461 Kühen mit Blinddarmdila-tation, -torsion und -retroflexion beschrieben, die vom 25. Juni 1997 bis zum 24. Juni 2008 im Departement für Nutztiere der Vetsuisse-Fakultät Zürich behan-delt wurden. 246 Kühe (53.4 %) wiesen eine Blinddarmdilatation, 142 Kühe (30.8 %) eine Blinddarmdilatation und -retroflexion und 73 Kühe (15.8 %) eine Blinddarmdilatation und -torsion au...

  3. Herstellung und Charakterisierung von Funktionsschichten mit kombinierter Schutz- und Sensoreigenschaft

    OpenAIRE

    Brunken, Hayo

    2013-01-01

    Im Mittelpunkt der vorliegenden Arbeit stand die Entwicklung neuer ferromagnetischer Schutzschichten für Hochtemperatur-Sensorsysteme. Hierbei war es das Ziel, eine fernabfragbare Messung der Temperatur und des Verspannungszustandes der Schicht zu ermöglichen. Hierzu wurden dünne FeCo/AlN-, Fe/B- sowie FeCo/Ti- Precursorschichten abgeschieden und anschließend wärmebehandelt, mit dem Ziel der Ausbildung gewünschter funktionaler Phasen. Die Analyse der Materialsysteme zeigte, das...

  4. Effiziente hochauflösende Röntgenemissionsspektrometrie mit Synchrotronstrahlung

    OpenAIRE

    Unterumsberger, Rainer

    2015-01-01

    Das Ziel der vorliegenden Arbeit bestand darin, durch die Erhöhung der Sensitivität eines wellenlängendispersiven Spektrometers (WDS) im Spektralbereich weicher Röntgenstrahlung Zugang zu hochauflösender Röntgenemissionsspetrometrie an nanoskaligen Materialien leichter Elemente und Übergangsmetallen zu erhalten. Die Erhöhung der Sensitivität wurde durch eine Refokussierung der anregenden Undulatorstrahlung erreicht. Mit der erhöhten Sensitivität des WDS konnten zum einen die chemischen Spezie...

  5. Characterization of a GEM-based scintillation detector with He-CF4 gas mixture in clinical proton beams.

    Science.gov (United States)

    Nichiporov, D; Coutinho, L; Klyachko, A V

    2016-04-21

    Accurate, high-spatial resolution dosimetry in proton therapy is a time consuming task, and may be challenging in the case of small fields, due to the lack of adequate instrumentation. The purpose of this work is to develop a novel dose imaging detector with high spatial resolution and tissue equivalent response to dose in the Bragg peak, suitable for beam commissioning and quality assurance measurements. A scintillation gas electron multiplier (GEM) detector based on a double GEM amplification structure with optical readout was filled with a He/CF4 gas mixture and evaluated in pristine and modulated proton beams of several penetration ranges. The detector's performance was characterized in terms of linearity in dose rate, spatial resolution, short- and long-term stability and tissue-equivalence of response at different energies. Depth-dose profiles measured with the GEM detector in the 115-205 MeV energy range were compared with the profiles measured under similar conditions using the PinPoint 3D small-volume ion chamber. The GEM detector filled with a He-based mixture has a nearly tissue equivalent response in the proton beam and may become an attractive and efficient tool for high-resolution 2D and 3D dose imaging in proton dosimetry, and especially in small-field applications. PMID:26992243

  6. Progress on The GEMS (Gravity Electro-Magnetism-Strong) Theory of Field Unification and Its Application to Space Problems

    International Nuclear Information System (INIS)

    Progress on the GEMS (Gravity Electro-Magnetism-Strong), theory is presented as well as its application to space problems. The GEMS theory is now validated through the Standard Model of physics. Derivation of the value of the Gravitation constant based on the observed variation of α with energy: results in the formula G congruent with (ℎ/2π)c/Mηc2 exp(-1/(1.61α)), where α is the fine structure constant,(ℎ/2π), is Planck's constant, c, is the speed of light, and Mηc is the mass of the ηcc Charmonium meson that is shown to be identical to that derived from the GEM postulates. Covariant formulation of the GEM theory is now possible through definition of the spacetime metric tensor as a portion of the EM stress tensor normalized by its own trace: gab = 4(FcaFcb)/(FabFab), it is found that this results in a massless ground state vacuum and a Newtonian gravitation potential φ = 1/2 E2/B2. It is also found that a Lorentz or flat-space metric is recovered in the limit of a full spectrum ZPF

  7. Characterization of a GEM-based scintillation detector with He-CF4 gas mixture in clinical proton beams

    Science.gov (United States)

    Nichiporov, D.; Coutinho, L.; Klyachko, A. V.

    2016-04-01

    Accurate, high-spatial resolution dosimetry in proton therapy is a time consuming task, and may be challenging in the case of small fields, due to the lack of adequate instrumentation. The purpose of this work is to develop a novel dose imaging detector with high spatial resolution and tissue equivalent response to dose in the Bragg peak, suitable for beam commissioning and quality assurance measurements. A scintillation gas electron multiplier (GEM) detector based on a double GEM amplification structure with optical readout was filled with a He/CF4 gas mixture and evaluated in pristine and modulated proton beams of several penetration ranges. The detector’s performance was characterized in terms of linearity in dose rate, spatial resolution, short- and long-term stability and tissue-equivalence of response at different energies. Depth-dose profiles measured with the GEM detector in the 115-205 MeV energy range were compared with the profiles measured under similar conditions using the PinPoint 3D small-volume ion chamber. The GEM detector filled with a He-based mixture has a nearly tissue equivalent response in the proton beam and may become an attractive and efficient tool for high-resolution 2D and 3D dose imaging in proton dosimetry, and especially in small-field applications.

  8. Design and Construction of a First Prototype Muon Tomography System with GEM Detectors for the Detection of Nuclear Contraband

    CERN Document Server

    Hohlmann, M; Grasso, L; Locke, J B; Quintero, A; Mitra, D

    2009-01-01

    Current radiation portal monitors at sea ports and international borders that employ standard radiation detection techniques are not very sensitive to nuclear contraband that is well shielded to absorb emanating radiation. Muon Tomography (MT) based on the measurement of multiple scattering of atmospheric cosmic ray muons traversing cargo or vehicles that contain high-Z material is a promising passive interrogation technique for solving this problem. We report on the design and construction of compact Micro-Pattern Gas Detectors for a small prototype MT station. This station will employ 10 tracking stations based on 30cm x 30cm low-mass triple-GEM detectors with 2D readout. Due to the excellent spatial resolution of GEMs it is sufficient to use a gap of only a few cm between tracking stations. Together with the compact size of the GEM detectors this allows the GEM MT station to be an order of magnitude more compact than MT stations using traditional drift tubes. We present details of the production and assemb...

  9. Building a large-area GEM-based readout chamber for the upgrade of the ALICE TPC

    CERN Document Server

    Gasik, Piotr

    2016-01-01

    A large Time Projection Chamber (TPC) is the main device for tracking and charged-particle identification in the ALICE experiment at the CERN LHC. After the second long shutdown in 2019-2020, the LHC will deliver Pb beams colliding at an interaction rate up to 50 kHz, which is about a factor of 100 above the present read-out rate of the TPC. To fully exploit the LHC potential the TPC will be upgraded based on the Gas Electron Multiplier (GEM) technology. A prototype of an ALICE TPC Outer Read-Out Chamber (OROC) was equipped with twelve large-size GEM foils as amplification stage to demonstrate the feasibility of replacing the current Multi Wire Proportional Chambers with the new technology. With a total area of $\\sim$0.76 m$^2$ it is the largest GEM-based detector built to date. The GEM OROC was installed within a test field cage and commissioned with radioactive sources.

  10. Chloride ion-catalyzed generation of difluorocarbene for efficient preparation of gem-difluorinated cyclopropenes and cyclopropanes

    KAUST Repository

    Wang, Fei

    2011-01-01

    A chloride ion-catalyzed generation of difluorocarbene from a relatively non-toxic and inexpensive precursor, Me3SiCF2Cl (1), under mild and neutral conditions leads to an efficient preparation of gem-difluorocyclopropenes and difluorocyclopropanes through [2 + 1] cycloaddition reactions with alkynes and alkenes, respectively. © 2011 The Royal Society of Chemistry.

  11. Study on the Development of Industry of Internet of Things Based on Competitive GEM Model in Fujian Province

    OpenAIRE

    Di Jun An; Li Hao

    2016-01-01

    Firstly, the basic theories of internet of things, competitive GEM model and industrial development in Fujian Province were studied in this paper. Then, the factors influencing the cultivation of industrial competitiveness of the internet of things was observed and finally the suggestions on enhancing the competitiveness of internet of things and strengthening the cultivation of talents of internet of things were put forward.

  12. Performance of a Large-Area GEM Detector Prototype for the Upgrade of the CMS Muon Endcap System

    CERN Document Server

    Abbaneo, D; Abbrescia, M; Abdelalim, A.A; Abi Akl, M; Ahmed, W; Ahmed, W; Altieri, P; Aly, R; Asawatangtrakuldee, C; Ashfaq, A; Aspell, P; Assran, Y; Awan, I; Bally, S; Ban, Y; Banerjee, S; Barria, P; Benussi, L; Bhopatkar, V; Bianco, S; Bos, J; Bouhali, O; Braibant, S; Buontempo, S; Calabria, C; Caponero, M; Caputo, C; Cassese, F; Castaneda, A; Cauwenbergh, S; Cavallo, F.R; Celik, A; Choi, M; Choi, K; Choi, S; Christiansen, J; Cimmino, A; Colafranceschi, S; Colaleo, A; Conde Garcia, A; Dabrowski, M.M; De Lentdecker, G; de Oliveira, R; De Robertis, G; Dildick, S; Dorney, B; Elmetenawee, W; Fabrice, G; Ferrini, M; Ferry, S; Giacomelli, P; Gilmore, J; Guiducci, L; Gutierrez, A; Hadjiiska, R.M; Hassan, A; Hauser, J; Hoepfner, K; Hohlmann, M; Hoorani, H; Jeng, Y.G; Kamon, T; Karchin, P.E; Kim, H.S; Krutelyov, S; Kumar, A; Lee, J; Lenzi, T; Litov, L; Loddo, F; Maerschalk, T; Magazzu, G; Maggi, M; Maghrbi, Y; Magnani, A; Majumdar, N; Mal, P.K; Mandal, K; Marchioro, A; Marinov, A; Merlin, J.A; Mohanty, A.K; Mohapatra, A; Muhammad, S; Mukhopadhyay, S; Naimuddin, M; Nuzzo, S; Oliveri, E; Pant, L.M; Paolucci, P; Park, I; Passeggio, G; Pavlov, B; Philipps, B; Phipps, M; Piccolo, D; Postema, H; Pugliese, G; Baranac, A.Puig; Radi, A; Radogna, R; Raffone, G; Ramkrishna, S; Ranieri, A; Riccardi, C; Rodrigues, A; Ropelewski, L; RoyChowdhury, S; Ryu, M S; Ryu, G; Safonov, A; Sakharov, A; Salva, S; Saviano, G; Sharma, A; Swain, S.K; Talvitie, J.P; Tamma, C; Tatarinov, A; Turini, N; Tuuva, T; Twigger, J; Tytgat, M; Vai, I; van Stenis, M; Venditi, R; Verhagen, E; Verwilligen, P; Vitulo, P; Wang, D; Wang, M; Yang, U; Yang, Y; Yonamine, R; Zaganidis, N; Zenoni, F; Zhang, A

    2014-01-01

    Gas Electron Multiplier (GEM) technology is being considered for the forward muon upgrade of the CMS experiment in Phase 2 of the CERN LHC. Its first implementation is planned for the GE1/1 system in the $1.5 < \\mid\\eta\\mid < 2.2$ region of the muon endcap mainly to control muon level-1 trigger rates after the second long LHC shutdown. A GE1/1 triple-GEM detector is read out by 3,072 radial strips with 455 $\\mu$rad pitch arranged in eight $\\eta$-sectors. We assembled a full-size GE1/1 prototype of 1m length at Florida Tech and tested it in 20-120 GeV hadron beams at Fermilab using Ar/CO$_{2}$ 70:30 and the RD51 scalable readout system. Four small GEM detectors with 2-D readout and an average measured azimuthal resolution of 36 $\\mu$rad provided precise reference tracks. Construction of this largest GEM detector built to-date is described. Strip cluster parameters, detection efficiency, and spatial resolution are studied with position and high voltage scans. The plateau detection efficiency is [97.1 $\\pm...

  13. Short-term H{\\alpha} line variations in Classical Be stars: 59 Cyg and OT Gem

    CERN Document Server

    KT, Paul; Subramaniam, Annapurni

    2016-01-01

    We present the optical spectroscopic study of two Classical Be stars, 59 Cyg and OT Gem obtained over a period of few months in 2009. We detected a rare triple-peak H$\\alpha$ emission phase in 59 Cyg and a rapid decrease in the emission strength of H$\\alpha$ in OT Gem, which are used to understand their circumstellar disks. We find that 59 Cyg is likely to be rapid rotator, rotating at a fractional critical rotation of $\\sim$ 0.80. The radius of the H$\\alpha$ emission region for 59 Cyg is estimated to be $R_d/R_*$ $\\sim$ 10.0, assuming a Keplerian disk, suggesting that it has a large disk. We classify stars which have shown triple-peaks into two groups and find that the triple-peak emission in 59 Cyg is similar to $\\zeta$ Tau. OT Gem is found to have a fractional critical rotation of $\\sim$ 0.30, suggesting that it is either a slow rotator or viewed in low inclination. In OT Gem, we observed a large reduction in the radius of the H$\\alpha$ emission region from $\\sim$ 6.9 to $\\sim$ 1.7 in a period of three mon...

  14. Oxygen isotope systematics of gem corundum deposits in Madagascar: relevance for their geological origin

    Science.gov (United States)

    Giuliani, Gaston; Fallick, Anthony; Rakotondrazafy, Michel; Ohnenstetter, Daniel; Andriamamonjy, Alfred; Ralantoarison, Théogène; Rakotosamizanany, Saholy; Razanatseheno, Marie; Offant, Yohann; Garnier, Virginie; Dunaigre, Christian; Schwarz, Dietmar; Mercier, Alain; Ratrimo, Voahangy; Ralison, Bruno

    2007-02-01

    The oxygen isotopic composition of gem corundum was measured from 22 deposits and occurrences in Madagascar to provide a gemstone geological identification and characterization. Primary corundum deposits in Madagascar are hosted in magmatic (syenite and alkali basalt) and metamorphic rocks (gneiss, cordieritite, mafic and ultramafic rocks, marble, and calc-silicate rocks). In both domains the circulation of fluids, especially along shear zones for metamorphic deposits, provoked in situ transformation of the corundum host rocks with the formation of metasomatites such as phlogopite, sakenite, and corundumite. Secondary deposits (placers) are the most important economically and are contained in detrital basins and karsts. The oxygen isotopic ratios (18O/16O) of ruby and sapphire from primary deposits are a good indicator of their geological origin and reveal a wide range of δ18O (Vienna Standard Mean Ocean Water) between 1.3 and 15.6‰. Metamorphic rubies are defined by two groups of δ18O values in the range of 1.7 to 2.9‰ (cordieritite) and 3.8 to 6.1‰ (amphibolite). “Magmatic” rubies from pyroxenitic xenoliths contained in the alkali basalt of Soamiakatra have δ18O values ranging between 1.3 and 4.7‰. Sapphires are classified into two main groups with δ18O in the range of 4.7 to 9.0‰ (pyroxenite and feldspathic gneiss) and 10.7 to 15.6‰ (skarn in marble from Andranondambo). The δ18O values for gem corundum from secondary deposits have a wide spread between -0.3 and 16.5‰. The ruby and sapphire found in placers linked to alkali basalt environments in the northern and central regions of Madagascar have consistent δ18O values between 3.5 and 6.9‰. Ruby from the placers of Vatomandry and Andilamena has δ18O values of 5.9‰, and between 0.5 and 4.0‰, respectively. The placers of the Ilakaka area are characterized by a huge variety of colored sapphires and rubies, with δ18O values between -0.3 and 16.5‰, and their origin is debated. A

  15. Application of the GEM Inventory Data Capture Tools for Dynamic Vulnerability Assessment and Recovery Modelling

    Science.gov (United States)

    Verrucci, Enrica; Bevington, John; Vicini, Alessandro

    2014-05-01

    A set of open-source tools to create building exposure datasets for seismic risk assessment was developed from 2010-13 by the Inventory Data Capture Tools (IDCT) Risk Global Component of the Global Earthquake Model (GEM). The tools were designed to integrate data derived from remotely-sensed imagery, statistically-sampled in-situ field data of buildings to generate per-building and regional exposure data. A number of software tools were created to aid the development of these data, including mobile data capture tools for in-field structural assessment, and the Spatial Inventory Data Developer (SIDD) for creating "mapping schemes" - statistically-inferred distributions of building stock applied to areas of homogeneous urban land use. These tools were made publically available in January 2014. Exemplar implementations in Europe and Central Asia during the IDCT project highlighted several potential application areas beyond the original scope of the project. These are investigated here. We describe and demonstrate how the GEM-IDCT suite can be used extensively within the framework proposed by the EC-FP7 project SENSUM (Framework to integrate Space-based and in-situ sENSing for dynamic vUlnerability and recovery Monitoring). Specifically, applications in the areas of 1) dynamic vulnerability assessment (pre-event), and 2) recovery monitoring and evaluation (post-event) are discussed. Strategies for using the IDC Tools for these purposes are discussed. The results demonstrate the benefits of using advanced technology tools for data capture, especially in a systematic fashion using the taxonomic standards set by GEM. Originally designed for seismic risk assessment, it is clear the IDCT tools have relevance for multi-hazard risk assessment. When combined with a suitable sampling framework and applied to multi-temporal recovery monitoring, data generated from the tools can reveal spatio-temporal patterns in the quality of recovery activities and resilience trends can be

  16. MIT Lincoln Laboratory: Physics and Technology in the National Interest

    Science.gov (United States)

    Ralston, Richard

    2001-03-01

    This year, MIT is celebrating the 50th anniversary of the founding of Lincoln Laboratory, which was formed at the request of the DoD with the initial goal of developing a national air defense system. In its 50 years, the Laboratory staff have made significant contributions in diverse areas including radar imaging, satellite communications, digital signal processing, computer science, semiconductor materials and solid state physics. The Laboratory has been true to its mission statement, which places strong emphasis on the application of advanced electronics to R&D in the national interest. Much of the technology is transitioned to U.S. industry for both government and commercial use. Annually more than 500 publications and meeting speeches are given, and cooperative developments with industry have targeted technology transitions ranging from next-generation photolithographic tools to microchip lasers. The Laboratory staff have been granted over 400 patents, and license to this intellectual property is at the core of many of the over 70 spin-off companies. MIT employs 2,300 people at Lincoln, including 1,200 professionals with degrees in physics, math, computer science, materials science and the engineering disciplines. Two-fifths of the professional staff are at the doctoral level; over two-thirds hold advanced degrees. This presentation will describe recent examples of research challenges for physicists in a multidisciplinary project-oriented environment.

  17. Behandlungskonzepte für Patienten mit malignen Gliomen

    Directory of Open Access Journals (Sweden)

    Oberndorfer S

    2009-01-01

    Full Text Available In der Behandlung von Patienten mit malignen Gliomen hat sich in den vergangenen Jahren die Standardtherapie der konkomitanten Radiochemotherapie nach dem so genannten „Stupp-Protokoll“ etabliert. Im Falle eines Nichtansprechens oder einer Tumorprogression ist die Therapieentscheidung nach wie vor nicht einheitlich und wird von Zentrum zu Zentrum unterschiedlich gehandhabt. Neue molekularbiologische und neuroradiologische Techniken zeigen zunehmend die Heterogenität dieser Tumoren auf und erklären auch teilweise das unterschiedliche Ansprechen auf verschiedene Therapieansätze. Patienten mit gleicher histologischer Diagnose zeigen unterschiedlichste genetische Veränderungen und unterschiedliches Wachstumsverhalten. Ziel zukünftiger Entwicklungen wird es sein, entsprechend den individuellen Eigenschaften der malignen Gliome auch individuelle Therapiekonzepte zu entwickeln. Vielversprechend scheint hier für die nähere Zukunft die Kombination von so genannten zielgerichteten Therapien und klassischen Chemotherapien wie Alkylantien. Um eine optimale Betreuung dieser Patienten zu gewährleisten, ist ein neuroonkologisches Tumor-Board mittlerweile internationaler Standard.

  18. MIT nuclear reactor laboratory high school teaching program

    International Nuclear Information System (INIS)

    For the last 6 years, the Massachusetts Institute of Technology (MIT) Nuclear Reactor Laboratory's academic and scientific staffa have been conducting evening seminars for precollege science teachers, parents, and high school students from the New England area. These seminars, as outlined in this paper, are intended to give general information on nuclear technologies with specific emphasis on radiation physics, nuclear medicine, nuclear chemistry, and ongoing research activities at the MIT research reactor. The ultimate goal is to create interest or build on the already existing interest in science and technology by, for example, special student projects. Several small projects have already been completed ranging from environmental research to biological reactions with direct student involvement. Another outcome of these seminars was the change in attitudes of science teachers toward nuclear technology. Numerous letters have been received from the teachers and parents stating their previous lack of knowledge on the beneficial aspects of nuclear technologies and the subsequent inclusion of programs in their curriculum for educating students so that they may also develop a more positive attitude toward nuclear power

  19. On Competitiveness of Agricultural Industrial Clusters in Hubei Province Based on GEM Model

    Institute of Scientific and Technical Information of China (English)

    CHEN De-gang

    2012-01-01

    Firstly, this paper summarizes concept of the agricultural industrial cluster and GEM model. Then, it analyzes the competitiveness of agricultural industrial clusters in Hubei Province from three aspects, namely, the foundation, enterprises and market. In the aspect of the foundation, Hubei Province has superior geographical location, rich natural resources, abundant human resources, diversified capital sources, and hardware and software facilities. In the aspect of enterprises, agricultural suppliers (farmers) are relatively scattered in Hubei Province, organizational level of relevant enterprises is constantly improved, and structure and strategy of enterprises are constantly innovated. In the aspect of market, the competition of agricultural products is fierce in local market, and it is difficult to explore external market. Finally, it presents countermeasures to improve the competitiveness of agricultural industrial clusters in Hubei Province, including building agricultural industrial park and cultivating key leading enterprises, strengthening innovation management, and increasing financial support.

  20. The origin of GEMS in IDPs as deduced from microstructural evolution of amorphous silicates with annealing

    CERN Document Server

    Davoisne, C; Leroux, H; D'Hendecourt, L B; Jones, A; Deboffle, D

    2006-01-01

    We present laboratory studies of the micro-structural evolution of an amorphous ferro-magnesian silicate, of olivine composition, following thermal annealing under vacuum. Annealing under vacuum was performed at temperatures ranging from 870 to 1020 K. After annealing spheroidal metallic nano-particles (2-50 nm) are found within the silicate films. We interpret this microstructure in terms of a reduction of the initial amorphous silicate FeO component, because of the carbon-rich partial pressure in the furnace due to pumping mechanism. Annealing in a controlled oxygen-rich atmosphere confirms this interpretation. The observed microstructures closely resemble those of the GEMS (Glass with Embedded Metal and Sulphides) found in chondritic IDPs (Interplanetary Dust Particles). Since IDPs contain abundant carbonaceous matter, a solid-state reduction reaction may have occurred during heating in the hot inner regions of the proto-solar disc. Related to this, the presence of forsterite grains grown from the amorphou...

  1. 3D field calculation of the GEM prototype magnet and comparison with measurements

    Energy Technology Data Exchange (ETDEWEB)

    Lari, R.J.

    1983-10-28

    The proposed 4 GeV Electron Microtron (GEM) is designed to fill the existing buildings left vacant by the demise of the Zero Gradient Synchrotron (ZGS) accelerator. One of the six large dipole magnets is shown as well as the first 10 electron orbits. A 3-orbit prototype magnet has been built. The stepped edge of the magnet is to keep the beam exiting perpendicular to the pole. The end guards that wrap around the main coils are joined together by the 3 shield plates. The auxiliary coils are needed to keep the end guards and shield plates from saturating. A 0.3 cm Purcell filter air gap exists between the pole and the yoke. Can anyone question this being a truly three-dimensional magnetostatic problem. The computer program TOSCA, developed at the Rutherford Appleton Laboratory by the Computing Applications Group, was used to calculate this magnet and the results have been compared with measurements.

  2. A dynamic method for charging-up calculations: the case of GEM

    CERN Document Server

    Correia, P M M; Azevedo, C D R; Silva, A L M; Veenhof, R; Nemallapudi, Mythra Varun; Veloso, J F C A

    2014-01-01

    The simulation of Micro Pattern Gaseous Detectors (MPGDs) signal response is an important and powerful tool for the design and optimization of such detectors. However, several attempts to simulate exactly the effective charge gain have not been completely successful. Namely, the gain stability over time has not been fully understood. Charging-up of the insulator surfaces have been pointed as one of the responsible for the difference between experimental and Monte Carlo results. This work describes two iterative methods to simulate the charging-up in one MPGD device, the Gas Electron Multiplier (GEM). The first method uses a constant step for avalanches time evolution, very detailed, but slower to compute. The second method uses a dynamic step that improves the computing time. Good agreement between both methods was reached. Despite of comparison with experimental results shows that charging-up plays an important role in detectors operation, should not be the only responsible for the difference between simulat...

  3. Triple-GEM detectors for the innermost region of the muon apparatus at the LHCb experiment

    CERN Document Server

    Poli-Lener, M; Bencivenni, G

    2005-01-01

    The LHCb experiment will take place at the future LHC accelerator at CERN and will start in 2007. It is a single arm spectrometer to precision measurements of CP violation and rare decays in the b quark sector. Recent experimental results have shown that CP violation is large in this sector. LHCb is designed with a robust and flexible trigger in order to extensively gain access to a wide spread of different physical processes involving the beauty particles. This will allow to over-constrain the Standard Model predictions about $\\mathcal{CP}$ violation, and to discover any possible inconsistency, which would reveal the presence of ''New Physics''. The work presented in this thesis has two main parts: the development of a charged particle detector based on Gas Electron Multiplication (GEM) and the study of luminosity measurements with the physical channels $Z^{0} \\rightarrow \\mu^{+} \\mu^{-}$ and $W^{\\pm} \\rightarrow \\mu^{\\pm} \

  4. Design and optimization of resistive anode for a two-dimensional imaging GEM detector

    Science.gov (United States)

    Ju, Xu-Dong; Dong, Ming-Yi; Zhao, Yi-Chen; Zhou, Chuan-Xing; Qun, Ou-Yang

    2016-08-01

    A resistive anode for two-dimensional imaging detectors, which consists of a series of high resistivity pads surrounded by low resistivity strips, can provide good spatial resolution while reducing the number of electronics channels required. The optimization of this kind of anode has been studied by both numerical simulations and experimental tests. It is found that to obtain good detector performance, the resistance ratio of the pads to the strips should be larger than 5, the nonuniformity of the pad surface resistivity should be less than 20%, a smaller pad width leads to a smaller spatial resolution, and when the pad width is 6 mm, the spatial resolution (σ) can reach about 105 μm. Based on the study results, a 2-D GEM detector prototype with optimized resistive anode is constructed and a good imaging performance is achieved. Supported by National Natural Science Foundation of China (11375219) and CAS Center for Excellence in Particle Physics (CCEPP)

  5. Fiber Bragg Grating sensors for deformation monitoring of GEM foils in HEP detectors

    CERN Document Server

    Benussi, L; Caponero, M; Muhammad, S; Passamonti, L; Piccolo, D; Pierluigi, D; Raffone, G; Russo, A; Saviano, G

    2015-01-01

    Fiber Bragg Grating (FBG) sensors have been so far mainly used in high energy physics (HEP) as high precision positioning and re-positioning sensors and as low cost, easy to mount, radiation hard and low space- consuming temperature and humidity devices. FBGs are also commonly used for very precise strain measurements. In this work we present a novel use of FBGs as flatness and mechanical tensioning sensors applied to the wide Gas Electron Multiplier (GEM) foils of the GE1/1 chambers of the Compact Muon Solenoid (CMS) experiment at Large Hadron Collider (LHC) of CERN. A network of FBG sensors has been used to determine the optimal mechanical tension applied and to characterize the mechanical stress applied to the foils. The preliminary results of the test performed on a full size GE1/1 final prototype and possible future developments will be discussed.

  6. Two-dimensional GEM imaging detector with delay-line readout

    Science.gov (United States)

    Guedes, G. P.; Breskin, A.; Chechik, R.; Vartsky, D.; Bar, D.; Barbosa, A. F.; Marinho, P. R. B.

    2003-11-01

    A 100×100 mm 2 2D imaging detector, based on a triple-GEM gaseous multiplier, striped x- y readout anode and discrete delay-line readout, is presented. The fast (2.1 ns tap -1) delay-line circuit was designed to match the anode-charge signal profile, namely its rise-time and length. The detector's imaging capability was systematically studied in Ar/CO 2 (70/30) with 5.9 keV X-rays; x- y resolution of σ=0.05 and 0.1 mm for top and bottom anode strips, respectively, and integral non-linearity of ˜0.15% are demonstrated.

  7. A GEM-based Time Projection Chamber for the AMADEUS experiment

    CERN Document Server

    Lener, M Poli; Corradi, G; Curceanu, C; D'Uffizi, A; Paglia, C; Sbardella, E; Scordo, A; Tagnani, D; Vidal, A Romero; Zmeskal, J

    2013-01-01

    In this paper we present the R&D activity on a new GEM-based TPC prototype for AMADEUS, a new experimental proposal at the DA{\\Phi}NE {\\Phi}-factory at the Laboratori Nazionali di Frascati (INFN), aiming to perform measurements of the low-energy negative kaons interactions in nuclei. Such innovative detector will equip the inner part of the experiment in order to perfom a better reconstruction of the primary vertex and the secondary particles tracking. A 10x10 cm2 prototype with a drift gap up to 15 cm was realized and succesfully tested at the {\\pi} M1 beam facility of the Paul Scherrer Institut (PSI) with low momentum hadrons. The measurements of the detector efficiency and spatial resolution have been performed. The results as a function of the gas gain, drift field, front-end electronic threshold and particle momentum are reported and discussed.

  8. Simulation of the time-projection chamber with triple GEMs for the LAMPS at RAON

    Science.gov (United States)

    Jhang, Genie; Lee, Jung Woo; Moon, Byul; Hong, Byungsik; Ahn, Jung Keun; Lee, Jong-Won; Lee, Kyong Sei; Kim, Young Jin; Lee, Hyo Sang

    2016-03-01

    The time-projection chamber (TPC) with triple gas-electron multipliers (GEMs) is designed for the large-acceptance multipurpose spectrometer (LAMPS) at the new radioactive ion-beam facility RAON, a pure Korean term for the accelerator complex, in Korea. The simulation environment has been set up to test the performance of the designed chamber, and the software package for analysis has been developed. Particle identification has been demonstrated to be possible up to 2 GeV/ c in momentum for particles with the charge number 1 and 2 by using the simulated heavy-ion events. The transverse-momentum resolutions are expected to be about 2% for protons and about 1.3% for pions in the relatively high-momentum region. The total reconstruction efficiencies are estimated to be about 90 and 80% for charged pions and protons, respectively.

  9. C-4 Gem-Dimethylated Oleanes of Gymnema sylvestre and Their Pharmacological Activities

    Directory of Open Access Journals (Sweden)

    Giovanni Di Fabio

    2013-12-01

    Full Text Available Gymnema sylvestre R. Br., one of the most important medicinal plants of the Asclepiadaceae family, is a herb distributed throughout the World, predominantly in tropical countries. The plant, widely used for the treatment of diabetes and as a diuretic in Indian proprietary medicines, possesses beneficial digestive, anti-inflammatory, hypoglycemic and anti-helmentic effects. Furthermore, it is believed to be useful in the treatment of dyspepsia, constipation, jaundice, hemorrhoids, cardiopathy, asthma, bronchitis and leucoderma. A literature survey revealed that some other notable pharmacological activities of the plant such as anti-obesity, hypolipidemic, antimicrobial, free radical scavenging and anti-inflammatory properties have been proven too. This paper aims to summarize the chemical and pharmacological reports on a large group of C-4 gem-dimethylated pentacyclic triterpenoids from Gymnema sylvestre.

  10. Conceptual design and development of GEM based detecting system for tomographic tungsten focused transport monitoring

    Science.gov (United States)

    Chernyshova, M.; Czarski, T.; Malinowski, K.; Kowalska-Strzęciwilk, E.; Poźniak, K.; Kasprowicz, G.; Zabołotny, W.; Wojeński, A.; Kolasiński, P.; Mazon, D.; Malard, P.

    2015-10-01

    Implementing tungsten as a plasma facing material in ITER and future fusion reactors will require effective monitoring of not just its level in the plasma but also its distribution. That can be successfully achieved using detectors based on Gas Electron Multiplier (GEM) technology. This work presents the conceptual design of the detecting unit for poloidal tomography to be tested at the WEST project tokamak. The current stage of the development is discussed covering aspects which include detector's spatial dimensions, gas mixtures, window materials and arrangements inside and outside the tokamak ports, details of detector's structure itself and details of the detecting module electronics. It is expected that the detecting unit under development, when implemented, will add to the safe operation of tokamak bringing the creation of sustainable nuclear fusion reactors a step closer. A shorter version of this contribution is due to be published in PoS at: 1st EPS conference on Plasma Diagnostics

  11. A cylindrical GEM detector with analog readout for the BESIII experiment

    Science.gov (United States)

    Amoroso, A.; Baldini, R.; Bertani, M.; Bettoni, D.; Bianchi, F.; Calcaterra, A.; Carassiti, V.; Cerioni, S.; Chai, J.; Cibinetto, G.; Cotto, G.; Mori, F. De; Destefanis, M.; Dong, J.; Dong, M.; Farinelli, R.; Fava, L.; Felici, G.; Fioravanti, E.; Garzia, I.; Gatta, M.; Greco, M.; Hu, J. F.; Johansson, T.; Leng, C.; Li, H.; Liu, Z.; Maggiora, M.; Marcello, S.; Marciniewski, P.; Melchiorri, M.; Mezzadri, G.; Morello, G.; Ouyan, Q.; Pacetti, S.; Patteri, P.; Rivetti, A.; Rosner, C.; Savrié, M.; Sosio, S.; Spataro, S.; Tskhadadze, E.; Wang, K.; Wang, L.; Wu, L.; Ji, X.; Ye, M.; Zallo, A.; Zhang, Y.; Zotti, L.

    2016-07-01

    A cylindrical GEM detector with analog readout is under development for the upgrade of the Inner Tracker of the BESIII experiment at IHEP (Beijing). The new detector will match the requirements for momentum resolution (σpt /pt ~ 0.5 % at 1 GeV) and radial resolution (σxy ~ 120 μm) of the existing drift chamber and will improve significantly the spatial resolution along the beam direction (σz ~ 150 μm) with very small material budget (less than 1.5% of X0). With respect to the state of the art the following innovations will be deployed: a lighter mechanical structure based on Rohacell, a new XV anode readout plane with jagged strip layout to reduce the parasitic capacitance, and the use of the analogue readout inside a high intensity magnetic field to have good spatial resolution without increasing the number of channels.

  12. Tomographic capabilities of the new GEM based SXR diagnostic of WEST

    Science.gov (United States)

    Jardin, A.; Mazon, D.; O'Mullane, M.; Mlynar, J.; Loffelmann, V.; Imrisek, M.; Chernyshova, M.; Czarski, T.; Kasprowicz, G.; Wojenski, A.; Bourdelle, C.; Malard, P.

    2016-07-01

    The tokamak WEST (Tungsten Environment in Steady-State Tokamak) will start operating by the end of 2016 as a test bed for the ITER divertor components in long pulse operation. In this context, radiative cooling of heavy impurities like tungsten (W) in the Soft X-ray (SXR) range [0.1 keV; 20 keV] is a critical issue for the plasma core performances. Thus reliable tools are required to monitor the local impurity density and avoid W accumulation. The WEST SXR diagnostic will be equipped with two new GEM (Gas Electron Multiplier) based poloidal cameras allowing to perform 2D tomographic reconstructions in tunable energy bands. In this paper tomographic capabilities of the Minimum Fisher Information (MFI) algorithm developed for Tore Supra and upgraded for WEST are investigated, in particular through a set of emissivity phantoms and the standard WEST scenario including reconstruction errors, influence of noise as well as computational time.

  13. Analysis of data recorded by the LCTPC equipped with a two layer GEM-system

    CERN Document Server

    Ljunggren, M

    2012-01-01

    wire based readout. The prototype TPC is placed in a 1 Tesla magnet at DESY and tested using an electron beam. Analyses of data taken during two different measurement series, in 2009 and 2010, are presented here. The TPC was instrumented with a two layer GEM system and read out using modified electronics from the ALICE experiment, including the programmable charge sensitive preamp-shaper PCA16. The PCA16 chip has a number of programmable parameters which allows studies to determine the settings optimal to the final TPC. Here, the impact of the shaping time on the space resolution in the drift direction was studied. It was found that a shaping time of 60 ns is the b...

  14. Conceptual design and development of GEM based detecting system for tomographic tungsten focused transport monitoring

    International Nuclear Information System (INIS)

    Implementing tungsten as a plasma facing material in ITER and future fusion reactors will require effective monitoring of not just its level in the plasma but also its distribution. That can be successfully achieved using detectors based on Gas Electron Multiplier (GEM) technology. This work presents the conceptual design of the detecting unit for poloidal tomography to be tested at the WEST project tokamak. The current stage of the development is discussed covering aspects which include detector's spatial dimensions, gas mixtures, window materials and arrangements inside and outside the tokamak ports, details of detector's structure itself and details of the detecting module electronics. It is expected that the detecting unit under development, when implemented, will add to the safe operation of tokamak bringing the creation of sustainable nuclear fusion reactors a step closer. A shorter version of this contribution is due to be published in PoS at: 1st EPS conference on Plasma Diagnostics

  15. Treatment planning with functional MRI; Strahlentherapieplanung mit der funktionellen MRT

    Energy Technology Data Exchange (ETDEWEB)

    Georg, P. [EBG MedAustron GmbH, Wiener Neustadt (Austria); Medizinische Universitaet Wien, Christian Doppler Labor fuer die Medizinische Strahlenforschung, Wien (Austria); Andrzejewski, P.; Georg, D. [Medizinische Universitaet Wien, Christian Doppler Labor fuer die Medizinische Strahlenforschung, Wien (Austria); Medizinische Universitaet Wien, Abteilung fuer medizinische Strahlenphysik, Univ. Klinik fuer Strahlentherapie, Wien (Austria); Pinker, K. [Medizinische Universitaet Wien, Christian Doppler Labor fuer die Medizinische Strahlenforschung, Wien (Austria); Medizinische Universitaet Wien, Abteilung fuer molekulare Bildgebung, Univ. Klinik fuer Radiologie und Nuklearmedizin, Wien (Austria)

    2015-12-15

    The aim of magnetic resonance imaging (MRI) guided radiotherapy is high precision in treatment delivery. With new developments it is possible to focus the high dose irradiation on the tumor while sparing the surrounding tissue. The achievements in precision of the treatment planning and delivery warrant equally precise tumor definition. In conventional radiation therapy it is necessary to carry out a planning computed tomography (CT). For many tumors there is also need for an additional morphological MRI because of more accurate tumor definition. In standard radiotherapy the tumor volume is irradiated with a homogeneous dose. The aim of functional multiparametric MRI is to visualize and quantify biological, physiological and pathological processes at the cellular and molecular levels. Based on this information it is possible to elucidate tumor biology and identify subvolumes of more aggressive behavior. They are often radiotherapy-resistant, leading to tumor recurrence thus requiring further dose escalation. The concept of inhomogeneous tumor irradiation according to its biological behavior is called dose painting. Dose painting is technically feasible. The expected clinical benefit is motivated by selective treatment adaptations based on biological tumor characteristics. Tumors show variable response to therapy underlining the need for individual treatment plans. This approach may lead not only to higher local control but also to better sparing of normal surrounding tissue. With the clinical implementation of dose painting, improvements in the therapeutic outcome can be expected. Due to the existing technical challenges, extensive collaboration between radiation oncologists, radiologists, medical physicists and radiation biologists is needed. (orig.) [German] Die Strahlentherapieplanung mit der funktionellen Magnetresonanztomographie (fMRT) zielt auf eine Hochpraezisionsradiotherapie ab. Mit den modernen Technologien ist es moeglich, die Strahlentherapie nahezu

  16. Dst Index in the 2008 GEM Modeling Challenge - Model Performance for Moderate and Strong Magnetic Storms

    Science.gov (United States)

    Rastaetter, Lutz; Kuznetsova, Maria; Hesse, Michael; Chulaki, Anna; Pulkkinen, Antti; Ridley, Aaron J.; Gombosi, Tamas; Vapirev, Alexander; Raeder, Joachim; Wiltberger, Michael James; Mays, M. L.; Fok, Mei-Ching H.; Weigel, Robert S.; Welling, Daniel T.

    2010-01-01

    The GEM 2008 modeling challenge efforts are expanding beyond comparing in-situ measurements in the magnetosphere and ionosphere to include the computation of indices to be compared. The Dst index measures the largest deviations of the horizontal magnetic field at 4 equatorial magnetometers from the quiet-time background field and is commonly used to track the strength of the magnetic disturbance of the magnetosphere during storms. Models can calculate a proxy Dst index in various ways, including using the Dessler-Parker Sckopke relation and the energy of the ring current and Biot-Savart integration of electric currents in the magnetosphere. The GEM modeling challenge investigates 4 space weather events and we compare models available at CCMC against each other and the observed values of Ost. Models used include SWMF/BATSRUS, OpenGGCM, LFM, GUMICS (3D magnetosphere MHD models), Fok-RC, CRCM, RAM-SCB (kinetic drift models of the ring current), WINDMI (magnetosphere-ionosphere electric circuit model), and predictions based on an impulse response function (IRF) model and analytic coupling functions with inputs of solar wind data. In addition to the analysis of model-observation comparisons we look at the way Dst is computed in global magnetosphere models. The default value of Dst computed by the SWMF model is for Bz the Earth's center. In addition to this, we present results obtained at different locations on the Earth's surface. We choose equatorial locations at local noon, dusk (18:00 hours), midnight and dawn (6:00 hours). The different virtual observatory locations reveal the variation around the earth-centered Dst value resulting from the distribution of electric currents in the magnetosphere during different phases of a storm.

  17. Wirksamkeit der modifizierten Dualtherapie mit Omeprazol und Amoxicillin bei Helicobacter pylori -Infektionen mit Metronidazol- und Clarithromycin-resistenten Stämmen : eine Pilotstudie

    OpenAIRE

    Schröder, Holger

    2002-01-01

    Die Bedeutung einer HP-Gastritis ist bekannt. Therapiestudien haben gezeigt, dass eine prätherapeutische Resistenz von HP gegenüber Metronidazol und/oder Clarithromycin zu einer Minderung der Eradikationsrate von 20-30% bis hin zum Versagen führt. Die Zahl der Patienten mit doppelresistentem HP-Stamm nimmt rasch zu. Dies macht die Suche nach einer alternativen bzw. Reservetherapie erforderlich. 49 Patienten mit kulturell nachgewiesener Doppelresistenz von HP gegen Metronidazol und...

  18. Cholesterin-Interaktion mit G-Protein-gekoppelten Rezeptoren und intrazelluläre Verteilung

    OpenAIRE

    Wiegand, Volker

    2002-01-01

    ZusammenfassungIn dieser Arbeit konnte gezeigt werden, dass neben dem Oxytocinrezeptor auch die anderen Rezeptoren der Familie der Neurohypophysenhormone, die Vasopressinrezeptoren, in der gleichen Weise in ihren Bindungseigenschaften von Cholesterin beeinflusst werden. Im Gegensatz dazu zeigt der Cholecystokininrezeptor Typ B keine direkte Wechselwirkung mit Cholesterin. Durch Austausch der Transmembranhelices 6 und 7 des Oxytocinrezeptors mit entsprechenden Bereichen des Cholecystokininreze...

  19. Festigkeitstheorien von anisotropen Stoffen mit sprödem Bruchverhalten

    Directory of Open Access Journals (Sweden)

    SZALAI, József

    2008-01-01

    Full Text Available Um die Ttragfähigkeit von Konstruktionen aus anisotropen Werkstoffenbeurteilen zu können, wird eine Festigkeitstheorie benötigt. Von den Festigkeitshypothesen, die imvorigen Jahrhundert aufgestellt wurden, können drei, als allgemeingültig betrachtet werden, das heisstsie können für alle Arten der Anisotropie des Werkstoffes und beliebige Spannungszuständeverwendet werden. Jede dieser Theorien kann durch eine Festigkeitsoberfläche (das ist eineHyperoberfläche im Raum der sechs Spannungskomponenten veranschaulicht werden. Jeder Punktdieser Fläche stellt einen Spannungszustand im Grenzzustand des Versagens dar und soll imFolgenden als Spannungspunkt bezeichnet werden. Für zähe Stoffe sind diese Oberflächen immerkonvex. Es ist zu beweisen, dass diese Oberflächen für Stoffe mit sprödem Bruch auch konkaveFlächenteile – im Einklang mit der Praxis – beinhalten können. Die Relationen derFestigkeitshypothesen können so umgestaltet werden, dass auf einer Seite der Bestimmungsgleichungein Ergänzungspotential, bzw. eine zu ihm proportionale Grösse bleibt. So interpretiert, behaupten dieTheorien von Mises und Tsai-Wu, dass das bis zum Bruch angehäufte Ergänzungspotential eineKonstante und somit unabhängig von der Orientierung der Hauptspannungen gegenüber derHauptachsen der Anisotropie ist. Diese unserer physikalischen Vorstellung widersprechendeSchlussfolgerung wird allein von dem Kriterium von Ashkenasi nicht gefolgt, es sagt im Gegenteilaus, dass das bis zum Bruch angehäufte Ergänzungspotential keine Konstante, sondern eine Funktionder Invarianten des Spannungszustandes und damit indirekt der Orientierung ist. UnsereFeststellungen gelten in erster Linie für das natürliche Holz und für die Holzwerkstoffe, können aber für jeden anisotropen Stoff mit sprödem Bruchverhalten zu erweitert werden.

  20. Charakterisierung und Anwendung von humanen, primären mikrovaskulären Endothelzellen mit erweiterter Proliferationsfähigkeit

    OpenAIRE

    Scheller, Katharina

    2013-01-01

    Das Arbeitsgebiet Tissue Engineering befasst sich mit der Klärung der Mechanismen, die der Funktionen verschiedener Gewebearten zu Grunde liegen sowie mit der Entwicklung alternativer Strategien zur Behandlung von Organversagen bzw. Organverlusten. Einer der kritischsten Punkte im Tissue Engineering ist die ausreichende Versorgung der Zellen mit Nährstoffen und Sauerstoff. Bioartifizielle Gewebe mit einer Dicke von bis zu 200 µm können mittels Diffusion ausreichend versorgt werden. Für dicker...

  1. Junge Männer mit Problemen Young Men with Problems

    Directory of Open Access Journals (Sweden)

    Friederike Schneider

    2006-11-01

    Full Text Available Die vielfältigen Verantwortungen junger jemenitischer Männer gegenüber ihren Familien stehen im Mittelpunkt dieser empirischen Untersuchung. Bei dem Werk handelt es sich um eine Lizenziatsarbeit in Form einer klassischen Ethnografie, basierend auf einer Feldforschung in den Jahren 2003 und 2004 in der Altstadt von Sana’a, Jemen. Das Fazit der gesamten Studie wird mit dem Titel Zuerst die Freunde, dann die Frau vorweggenommen.The diverse responsibilities of young Yemenite men with regard to their families are the central theme of this empirical study. This text can be described as a classic ethnography that is based on fieldwork the licentiate performed in the old town of Sana’a, Jemen in 2003 and 2004. The conclusion of the entire study is already anticipated by the title of the work: First Come the Friends, then the Wife (Zuerst die Freunde, dann die Frau.

  2. Operating experience with innovative environmental technologies; Betriebserfahrungen mit innovativen Umwelttechnologien

    Energy Technology Data Exchange (ETDEWEB)

    Spindler, H.; Bauermeister, U.; Kliche, H.; Seiffarth, K. (comps.)

    2000-03-01

    The MUT '99 (Merseburger Umwelt-Tag) discussed modern processes, technologies and plants for treatment and utilisation of waste. The conference was attended by industrial organisations and scientific institutions. [German] Der 9. Merseburger Umwelt-Tag MUT '99 steht unter dem Motto 'Betriebserfahrungen mit innovativen Umwelttechnologien - Moderne wirtschaftliche Verfahren, Technologien und Anlagen zur Behandlung/Verwertung nichtvermeidbaren Abfalls', wobei der Begriff 'Abfall' sich letztlich auf alle Umweltmedien bezieht. Entsprechend dem Motto dieser Tagung stellen Unternehmen, Betriebe und wissenschaftliche Einrichtungen ihre Erfahrungen auf dem Gebiet der Umwelttechnologien vor, um Entwicklungen auf diesem Gebiet einer breiten Diskussion zu eroeffnen. Dabei soll es insbesondere um die Behandlung nicht vermeidbarer Abfaelle und Abwaesser gehen. (orig.)

  3. Pathophysiologie des Kollagenstoffwechsels bei Patienten mit Induratio penis plastica (IPP

    Directory of Open Access Journals (Sweden)

    Lahme S

    2000-01-01

    Full Text Available Die Pathogenese der IPP ist bis heute nicht geklärt. Histopathologische Untersuchungen zeigen, daß der Kollagenstoffwechsel eine Rolle spielt. Dies veranlaßte uns zur genauen Analyse der Kollagenstoffwechselparameter bei IPP. Bei 11 Patienten mit IPP und 11 Kontrollpersonen wurden Kollagenstoffwechselparameter (Prokollagen III [PIIIP], PMN-Elastase [PMN-E], Fibronektin [FN], Fibronektinrezeptor [FN-R] und alpha1-Proteinase-Inhibitor [alpha1-PI] im cavernösen und peripheren Blut bestimmt. PMN-E, PIIIP, FN und FN-R waren in den beiden Untersuchungsgruppen nicht unterschiedlich. Die peripher venösen unterschieden sich nicht von den cavernösen Blutproben. Sowohl im peripher venös (158,55 mg/dl als auch im cavernös entnommenen Blut (168,29 mg/dl war die Konzentration des a1-PI signifikant niedriger als in der Kontrollgruppe (214,82 mg/dl. An einem zweiten Kollektiv von 23 Patienten wurden Analysen des Phänotyps für alpha1-PI im Hinblick auf das Vorliegen von genetisch determinierten Mangelallelen vorgenommen. Hier zeigte sich kein signifikanter Unterschied zu einem Kontrollkollektiv von 19 gesunden Probanden. Die alpha1-PI Erniedrigung der IPP-Patienten ist signifikant und liegt unterhalb des Normalwertbereichs für die gesunde Population. Ein Mangel an alpha1-PI kann zur Aktivitätserhöhung der Proteasen und zum Umbau des Kollagengewebes führen. Möglicherweise kommt es zusammen mit einem lokal wirksamen Einflußfaktor schließlich zur dystrophen Kalzifikation. Die humangenetischen Untersuchungen sprechen nicht für eine genetische Determinierung des alpha1-PI-Mangels, sondern legen eine erworbene hepatische Störung nahe.

  4. Patient mit Ostiumstenose-Hauptstamm und Bifurkationsstenose - R. interventricularis anterior / R. diagonalis

    Directory of Open Access Journals (Sweden)

    Kerschner K

    2005-01-01

    Full Text Available Die Indikation zu Eingriffen am Hauptstamm und komplexen Bifurkationsstenosen wird auch nach Einführung von Drug-eluting- Stents und neuen Techniken kontrovers diskutiert. Im folgenden wird über eine kombinierte Hauptstamm- und Bifurkationsintervention berichtet. Anamnese: Ein 66jähriger Patient mit seit zwei Monaten zunehmender Belastungsdyspnoe Stadium III (NYHA, verbunden mit thorakalem Oppressionsgefühl. Zustand nach zerebralem Insult mit geringen Residuen, permanentes Vorhofflimmern, unzureichend eingestellte Hypertonie, geringe Nierenfunktionseinschränkung, Hypercholesterinämie. Invasive Abklärung: Ventrikulographie: ausgedehnte Akinese diaphragmal, Hypokinesie des Restventrikels, Auswurffraktion 29 %. Angiographie: 50 % Ostiumstenose-Hauptstamm, Bifurkationsstenose R. interventricularis anterior (LAD mit dem großen 1. diagonalen Ast jeweils 90 % (echte Bifurkation Typ IV ICPS-Klassifikation, Y konfiguriert (Abb. 1. Geringe Sklerose der klein angelegten A. circumflexa, proximaler Verschluß rechte Koronararterie mit Kollateralen von links zur diffus sklerotischen Peripherie. Nach entsprechender Aufklärung über die Therapiemöglichkeiten wurde eine Bypass-Operation vom Patienten nicht gewünscht und die Intervention durchgeführt. Intervention: Führungskatheter EBU 4 7F (Launcher, Medtronic. Sondierung beider Äste mit einem BMW-Führungsdraht (Balance Middleweight, Guidant Corp. und sequentielle Vordehnung R. diagonalis und LAD mit einem 2,5 / 20 mm-Ballon (Hypro Pegaso Sorin, Biomedica mit 16 atm. Plazierung eines 2,75 / 24 mm-Taxus-Express-2-Stent (Boston Scientific im R. diagonalis und eines 3,0 / 28 mm-Taxus-Express-2-Stent im LAD und Implantation in Crush-Technik (Abb. 2, jeweils 14 atm, mit dem Stent im R. diagonalis als gecrushtem Stent. Resondierung des R. diagonalis und Vordehnung des Abganges mit einem 1,5 und 2,5 mm-Ballon mit 20 atm und anschließende Kissing-Ballondilatation R. diagonalis 2,5 mm und LAD 3,0 mm

  5. Design, synthesis and in vivo anti-hyperglycemic activity of gem-dimethyl-bearing C-glucosides as SGLT2 inhibitors

    Institute of Scientific and Technical Information of China (English)

    Wen Jing Zhao; Yong Heng Shi; Gui Long Zhao; Yu Li Wang; Hua Shao; Li Da Tang; Jian Wu Wang

    2011-01-01

    A series of gem-dimethyl-bearing C-glucosides were designed and synthesized as SGLT2 inhibitors, with anhydrous aluminum chloride-mediated Friedel-Crafts alkylation to construct the gem-dimethyl functionality being the key step. The in vivo anti-hyperglycemic activity was evaluated with mice oral glucose tolerance test (OGTT), and all the synthesized compounds showed significant but less potent anti-hyperglycemic activity than the positive control dapagliflozin.

  6. Manual GEM 1.1.1 : greenhouse emission model, exposure assessment tool for plant protection products used in greenhouse crop cultivation

    OpenAIRE

    Wipfler, E.L.; Vink, C.; Horst, ter, M.M.S.; Jong, de, P.F.

    2015-01-01

    Deze handleiding is ter ondersteuning van de gebruiker van het software instrument GEM 1.1.1 (Greenhouse Emission Model 1.1.1). GEM 1.1.1 bevat de Nederlandse glastuinbouw blootstellingscenario’s zoals beschreven in Van der Linden et al. (2015) en Wipfler et al. (2015a) en berekent blootstellingconcentraties van gewasbeschermingsmiddelen voor de beschermdoelen: ‘Aquatisch ecosysteem’ en ‘Grondwater as bron van drinkwater’ als onderdeel van de milieurisicobeoordeling. Het instrument is ontwikk...

  7. VizieR Online Data Catalog: Radial velocities of 1 Gem (Lane+, 2014)

    Science.gov (United States)

    Lane, B. F.; Muterspaugh, M. W.; Griffin, R. F.; Scarfe, C. D.; Fekel, F. C.; Williamson, M. H.; Eaton, J. A.; Shao, M.; Colavita, M. M.; Konacki, M.

    2016-05-01

    Extensive radial-velocity measurements of the 1 Gem system have been obtained in four separate campaigns spanning 40yr, including data from eight different instruments. Between 1969 and 2009 R.F.G. acquired a total of 128 observations of 1 Gem using the original radial-velocity spectrometer at Cambridge; a second-generation, computerized instrument at Palomar; the CORAVEL spectrometer at Haute Provence Observatory (OHP), and most recently, the Cambridge CORAVEL. The "Cambridge CORAVEL" operates at the Coude focus of the 36inch reflector on the home site of the Cambridge Observatories, Madingley Road, Cambridge, England. The Cambridge and Palomar data are referred to as data set A, while the OHP data are labeled set B. The data for components A and Ba are provided in Table1. A series of observations of 1 Gem has been obtained by C.D.S. with the Dominion Astrophysical Observatory (DAO) radial-velocity spectrometer. Observations were begun early in 1980 and continued until the end of 2003. The DAO velocities of components A and Ba are listed in Table2. The total number of acceptable velocities from DAO radial-velocity scanner observations is 123 of the primary star and 107 of the brighter component of the close pair. The third component was not detectable in the DAO traces. We identify the DAO observations as data set C. >From 1983 through 2009 F.C.F. obtained observations at the Kitt Peak National Observatory (KPNO) with the 0.9m coude feed telescope, coude spectrograph, and several different CCD detectors. All of the spectrograms were acquired with a Texas Instruments (TI) CCD except for five that were obtained in 1983 with an RCA CCD and a single observation in 2008 September with a Tektronix CCD. All those observations were centered near 6430Å and had typical signal-to-noise ratios of about 250. The numerous TI CCD spectra have a wavelength range of just 84Å and a resolution of 0.21Å. The 86 velocities of component A and 80 of component Ba are listed in Table3

  8. High granularity tracker based on a Triple-GEM optically read by a CMOS-based camera

    Science.gov (United States)

    Marafini, M.; Patera, V.; Pinci, D.; Sarti, A.; Sciubba, A.; Spiriti, E.

    2015-12-01

    The detection of photons produced during the avalanche development in gas chambers has been the subject of detailed studies in the past. The great progresses achieved in last years in the performance of micro-pattern gas detectors on one side and of photo-sensors on the other provide the possibility of making high granularity and very sensitive particle trackers. In this paper, the results obtained with a triple-GEM structure read-out by a CMOS based sensor are described. The use of an He/CF4 (60/40) gas mixture and a detailed optimization of the electric fields made possible to obtain a very high GEM light yield. About 80 photons per primary electron were detected by the sensor resulting in a very good capability of tracking both muons from cosmic rays and electrons from natural radioactivity.

  9. Correction of distortion for optimal image stacking in Wide Field Adaptive Optics: Application to GeMS data

    CERN Document Server

    Bernard, A; Neichel, B; Fusco, T; Bounissou, S; Samal, M; Andersen, M; Zavagno, A; Plana, H

    2016-01-01

    The advent of Wide Field Adaptive Optics (WFAO) systems marks the beginning of a new era in high spatial resolution imaging. The newly commissioned Gemini South Multi-Conjugate Adaptive Optics System (GeMS) combined with the infrared camera Gemini South Adaptive Optics Imager (GSAOI), delivers quasi diffraction-limited images over a field of 2 arc-minutes across. However, despite this excellent performance, some variable residues still limit the quality of the analyses. In particular, distortions severely affect GSAOI and become a critical issue for high-precision astrometry and photometry. In this paper, we investigate an optimal way to correct for the distortion following an inverse problem approach. Formalism as well as applications on GeMS data are presented.

  10. Low Cost DNA Molecular Weight Marker: Primer-Directed Synthesis from pGEM-T Easy Vector

    Directory of Open Access Journals (Sweden)

    Siriporn RIYAJAN

    2011-06-01

    Full Text Available A low cost DNA molecular weight marker was produced by a marker primer-directed synthetic method using pGEM-T Easy vector as the DNA template. Seven primers were used to amplify eight different DNA fragments, which were 150, 300, 375, 500, 700, 1,000, 1,200 and 1,625 bp, from bacterial culture containing pGEM-T Easy vector. Polymerase chain reactions (PCR for all marker loci required the same optimal annealing temperature, which allowed all the PCR to be completed in a single run. To obtain the molecular weight marker, the PCR product of each locus was mixed together and directly used as marker without any further purification. This custom made molecular weight marker was found to be approximately 17 to 49 times less expensive than other commercial 100 bp DNA ladder markers.Graphical abstract

  11. High granularity tracker based on a Triple-GEM optically read by a CMOS-based camera

    CERN Document Server

    Marafini, Michela; Pinci, Davide; Sarti, Alessio; Sciubba, A; Spiriti, Eleuterio

    2015-01-01

    The detection of photons produced during the avalanche development in gas chambers has been well studied in the past. The great progresses achieved in last years in the performance of micro-pattern gas detectors on one side and of photo-sensors on the other provide the possibility of making high granularity and very sensitive particle trackers. In this paper, the results obtained with a triple-GEM structure read-out by a CMOS based sensor are described. The use of an He/CF$_4$ (60/40) gas mixture and a suitable study of the electric fields made possible to optimise GEM light yield. About 100 photons per primary electron were detected by the sensor resulting in a very good capability of tracking muons from cosmic rays.

  12. Inseltransplantation als Therapieoption bei Diabetes mellitus Typ 1: Für wen, mit welchem Ziel, mit welchem Erfolg?

    Directory of Open Access Journals (Sweden)

    Ludwig B

    2014-01-01

    Full Text Available Die Inseltransplantation hat sich als Behandlungsoption für Patienten mit Diabetes mellitus Typ 1 etabliert. In den meisten Zentren wird die Indikation gestellt, wenn konventionelle Therapiemethoden versagen und Patienten durch eine hochlabile Stoffwechsellage und rezidivierende Hypoglykämien gefährdet sind. Hintergrund für diese strikte Indikationsstellung ist die Notwendigkeit einer dauerhaften Immunsuppression und der kritische Mangel an verfügbaren Spenderorganen. Durch die Wiederherstellung einer endogenen Insulinsekretion kommt es zu einer zuverlässigen Stabilisierung des Blutzuckerprofils, Vermeidung von Hypoglykämien und Verhinderung bzw. Stabilisierung von Spätkomplikationen. Damit einher geht eine deutliche Verbesserung der Lebensqualität. Das Erreichen einer kompletten Insulinunabhängigkeit ist dabei nicht vorrangiges Therapieziel.

  13. Rekonstruktion mit Netz beim komplexen Prolaps der Frau: Was hilft es der Patientin wirklich?

    Directory of Open Access Journals (Sweden)

    Hierl J

    2010-01-01

    Full Text Available Einleitung: Der komplexe Genitaldeszensus der Frau geht oftmals mit einer deutlichen Einschränkung der Lebensqualität (LQ einher. Dennoch ist der Endpunkt der meisten klinischen Analysen rein anatomischer und funktioneller Natur. In der vorliegenden Untersuchung wurden die Einflüsse der operativen Rekonstruktion mit einem Netz prospektiv auf die LQ evaluiert. Patienten und Methoden: Bei insgesamt 111 Patientinnen mit Deszensus erfolgte zwischen 08/2005 und 12/2007 eine operative Versorgung mittels vaginaler Netzeinlage (anteriorer bzw. kompletter Mesh-Repair. Die LQ wurde prospektiv prä- und postoperativ anhand standardisierter LQ-Fragebögen erfasst. Ergebnisse: Präoperativ zeigte sich bei den Patientinnen eine signifikant reduzierte LQ gegenüber einem Normalkollektiv (p 0,01. Bei 7 % der Patientinnen mit anteriorem, und bei 11 % mit komplettem Mesh-Repair lag postoperativ kein adäquates klinisches Ergebnis vor. In diesem Kollektiv zeigte sich kein signifikanter Unterschied in den LQ-Tests prä- und postoperativ. Bei gutem postoperativem Ergebnis zeigte sich in der Gruppe mit anteriorer Netzeinlage lediglich bei 45 % (p = 0,021, bei kompletter Netzeinlage nur bei 31 % (p = 0,041 eine signifikant verbesserte LQ. Bei kleiner Fallzahl und kurzem Nachbeobachtungszeitraum kann eine gültige Aussage bezüglich der LQ nach Deszensuschirurgie mit Netzeinlage jedoch noch nicht getroffen werden.

  14. Study on the Development of Industry of Internet of Things Based on Competitive GEM Model in Fujian Province

    Directory of Open Access Journals (Sweden)

    Di Jun An

    2016-01-01

    Full Text Available Firstly, the basic theories of internet of things, competitive GEM model and industrial development in Fujian Province were studied in this paper. Then, the factors influencing the cultivation of industrial competitiveness of the internet of things was observed and finally the suggestions on enhancing the competitiveness of internet of things and strengthening the cultivation of talents of internet of things were put forward.

  15. A how-to approach for a 3D simulation of charge transfer characteristics in a gas electron multiplier (GEM)

    CERN Document Server

    Sharma, A

    1999-01-01

    In this paper a detailed description of how to simulate charge transfer processes in a gaseous device is presented, taking the gas electron multiplier (GEM) as an example. A 3-dimensional simulation of the electric field and avalanche is performed. Results on charge transport are compared to experiment and agree within experimental errors; the avalanche mechanism and positive ion feedback are studied. The procedures used in the simulation are described in detail, and program scripts are appended. (15 refs).

  16. SECS/GEM标准模型分析及应用%Research of SECS/GEM standard model and application

    Institute of Scientific and Technical Information of China (English)

    张鹏程; 张红雨; 陈杨

    2011-01-01

    SECS/GEM是半导体自动化生产中广泛采用的一个行业标准。首先介绍了SECS/GEM标准的整体框架,并分析了其行业发展状况,然后依次说明了SECSⅠ/Ⅱ、GEM、HSMS各个分层标准的数据报文格式、传输控制模型、状态转换模型以及相互间的通信控制方式等,最后分析了该标准在我国半导体自动化生产中的应用状况。实践表明,SECS/GEM标准设计严谨,适应面广,在我国半导体工业中应用前景广阔。%The SECS/GEM is an industry standard which is widely used in the automation of semiconductor.In this paper,the overall standard frame of SECS/GEM is introduced,and its industry development is analyzed.After that,SECSⅠ/Ⅱ,GEM and HSMS's stratification standard's data message format,transmission control model,the state transition model and mutual communication control mode are illustrated.Finally,the standard's application in our semiconductor's automatic production is analyzed.The practice shows that the SECS/GEM standard with a perfect design has a wide application prospect in homeland's semiconductor industy.

  17. Gemcitabine, cisplatin and methylprednisolone (GEM-P) is an effective salvage regimen in patients with relapsed and refractory lymphoma

    OpenAIRE

    Ng, M; Waters, J; Cunningham, D.; Chau, I; Horwich, A.; Hill, M; Norman, A R; Wotherspoon, A; Catovsky, D.

    2005-01-01

    There is currently no standard salvage chemotherapy regimen in relapsed and refractory lymphoma. Gemcitabine is a novel nucleoside analogue, which acts synergistically with cisplatin both in vitro and in clinical studies. We evaluated the combination of gemcitabine, cisplatin and methylprednisolone (GEM-P) in 41 heavily pretreated patients with relapsed and refractory Hodgkin's and non-Hodgkin's lymphoma. The best-achieved response rate (RR) was 79% (95% CI 64–91), with a complete RR of 21%. ...

  18. Impact of urban parameterization on high resolution air quality forecast with the GEM – AQ model

    Directory of Open Access Journals (Sweden)

    J. W. Kaminski

    2012-04-01

    Full Text Available The aim of this study is to assess the impact of urban cover on high-resolution air quality forecast simulations with the GEM-AQ model. The impact of urban area on the ambient atmosphere is non-stationary and short-term variability of meteorological conditions may result in significant changes of the observed intensity of urban heat island and pollutant concentrations. In this study we used the Town Energy Balance (TEB parameterization to represent urban effects on modelled meteorological and air quality parameters at the final nesting level with horizontal resolution of ~5 km over Southern Poland. Three one-day cases representing different meteorological conditions were selected and the model was run with and without the TEB parameterization. Three urban cover categories were used in the TEB parameterization: mid-high buildings, sparse buildings and a mix of buildings and nature. Urban cover layers were constructed based on an area fraction of towns in a grid cell. To analyze the impact of urban parameterization on modelled meteorological and air quality parameters, anomalies in the lowest model layer for the temperature, wind speed and pollutant concentrations were calculated. Anomalies of the specific humidity fields indicate that the use of the TEB parameterization leads to a systematic reduction of moisture content in the air. Comparison with temperature and wind speed measurements taken at urban background monitoring stations shows that application of urban parameterization improves model results. For primary pollutants the impact of urban areas is most significant in regions characterized with high emissions. In most cases the anomalies of NO2 and CO concentrations are negative. This reduction is most likely caused by an enhanced vertical mixing due to elevated surface temperature and modified vertical stability. Although the outcome from this study is promising, it does not give an answer concerning the benefits of using TEB in the GEM

  19. Control and supervision of a time projection chamber with GEM readout

    International Nuclear Information System (INIS)

    To get a deeper understanding of the structure of nucleons and the strong interaction binding the constituents inside, the CBELSA/TAPS experiment investigates the resonance spectrum of baryons by meson photoproduction within the scope of the SFB/TRR 16 ''Subnuclear Structure of Matter''. In order to support and expand the physical program, the existing Inner Detector will be replaced by a Time Projection Chamber (TPC) within the next few years. This allows for the detection of charged reaction channels, which can't be measured with the CBELSA/TAPS experiment up to now, as well as for particle identification from the specific energy loss. A First prototype with GEM foils for charge amplification in front of the readout plane and suitable size for the CBELSA/TAPS experiment was built in collaboration with the TU Munich, the detector laboratory of the GSI in Darmstadt and the Stefan-Meyer-Institute of the University Vienna. The TPC has been commissioned successfully within the FOPI experiment at the GSI during several test beam campaigns. Additionally, systematic studies have been carried out with a smaller Test-TPC using a TestBench providing an accurate external track definition. As the electron drift velocity in the TPC volume is a crucial parameter for the exact track reconstruction, detailed simulations of the drift velocity and its dependency on external parameters, such as drift voltage, pressure, gas flow or temperature, have been carried out. The results of these simulations recommend a constant monitoring of all examined parameters to allow a reasonable use of the simulated drift velocities. For this purpose, and to ensure a safe and stable operation of the TPCs and the other detectors on the TestBench, the required hardware, the control software based on a data base and a graphical user interface were designed and constructed as the main part of this work. With this so-called SlowControl, it was possible to measure, control and store several parameters - e

  20. Kombinierte radiologisch-interventionelle und radiotherapeutische Behandlung von Patienten mit zentralen Gallengangsmalignomen

    Directory of Open Access Journals (Sweden)

    Riedmann E

    2005-01-01

    Full Text Available Einleitung: In einer retrospektiven Analyse von 24 Patienten mit inoperablen oder nicht radikal resezierten Karzinomen des Gallentraktes wurde der Einfluß einer HDR-(high-dose-rate192-Ir-Brachytherapie oder der kombinierten Tele-/Brachytherapie auf Überlebenszeit und Verbesserung der Lebensqualität untersucht. Methode und Material: Von 1996 bis 2001 wurden 24 Patienten mit einem Karzinom, welches die extrahepatischen Gallenwege obstruierte (16 Klatskin-Tumoren, 6 Gallenblasenkarzinome, 2 Metastasen eines GI-Tumors, einer palliativen Radiatio unterzogen. 14 von 24 Patienten wurden bei einem lokal fortgeschrittenen inoperablen Tumor, 5 Patienten nach einer R1-Resektion und 5 Patienten im Rezidiv behandelt. Bei allen Patienten wurde eine perkutane transhepatische Cholangiographie (PTC und anschließend die Implantation eines oder mehrerer selbstexpandierbarer Stents zur Behandlung der biliären Okklusion durchgeführt. 23 Patienten erhielten eine endoluminale Brachytherapie, 10 davon kombiniert mit einer Teletherapie; ein Patient erhielt eine alleinige Teletherapie. Im ersten Jahr wurde sechs Patienten die Brachytherapie mit einer Dosis von 15 Gray (Gy in drei Fraktionen verabreicht. Ab 1997 wurden 17 Patienten mit hyperfraktionierter Brachytherapie (2 x täglich mit einer mittleren Dosis von 20 Gy (5 x 4 Gy behandelt. Die mittlere Dosis der Teletherapie in beiden Gruppen betrug 40 Gy (Range 22–60 Gy. Ergebnisse: Das mediane Überleben für alle Patienten betrug 7,7 Monate. Patienten, die mit hyperfraktionierter Brachytherapie behandelt wurden, zeigten einen Trend zu einem verlängerten Überleben mit 11,6 Monaten verglichen mit 5,7 Monaten in der konventionell behandelten Gruppe. Die akuten Nebenwirkungen waren moderat.

  1. Erhöhter oxidativer Streß bei Patienten mit instabiler Angina pectoris

    Directory of Open Access Journals (Sweden)

    Bodlaj G

    1998-01-01

    Full Text Available Die instabile Angina pectoris führt oft zum akuten Myokardinfarkt. Da die Lipid-Peroxidation im Verdacht steht, chronische und akute Ereignisse der Atherosklerose und der koronaren Herzkrankheit zu fördern, untersuchten wir die Lipid-Peroxidations-Parameter und alpha-Toco-pherol-Spiegel bei 100 KHK-Patienten und verglichen sie mit denen einer entprechenden Kontrollgruppe. 50 konsekutive Patienten mit stabiler Angina pectoris (SAP und 50 konsekutive Patienten mit instabiler Angina pectoris (IAP wurden untersucht und mit 100 klinisch gesunden Personen verglichen. Zusätzlich zur herkömmlichen Lipid- und Lipoprotein-Analyse wurden die Lipid-Peroxidations-Produkte als Hydroperoxide und Thiobarbituric acid reactive substances (TBARS gemessen. Die konjugierten Diene wurden nur bei den Patienten bestimmt. Da alpha-Tocopherol eines der wichtigsten Antioxidantien ist, wurde es ebenfalls quantifiziert. Wie erwartet hatten die Patienten wesentlich höhere Cholesterin-, Triglyzerid-, LDL-C- und Lp(a-Spiegel und niedrigere HDL-C-Spiegel als die Kontrollgruppe. Als die Patienten in Gruppen mit stabiler und instabiler Angina pectoris geteilt wurden, waren Peroxide und TBARS in der letzteren Gruppe wesentlich höher als bei den anderen Patienten und der Kontrollgruppe. Auch konjugierte Diene waren eindeutig höher bei den Patienten mit instabiler Angina pectoris. Der alpha-Tocopherol-Gesamtspiegel war in allen 3 Gruppen vergleichbar, aber der alpha-Tocopherol-Gehalt pro LDL-Partikel war bei den Patienten mit IAP am niedrigsten, gefolgt von denen mit SAP und der Kontrollgruppe. Wir schließen daraus, daß die Lipid-Peroxidations-Parameter bei Patienten mit IAP erhöht sind und SAP-Patienten von IAP-Patienten unterscheiden.

  2. Towards an automatic system for monitoring of CN2 and wind speed profiles with GeMS

    CERN Document Server

    Masciadri, E; Guesalaga, A; Turchi, A

    2016-01-01

    Wide Field Adaptive Optics (WFAO) systems represent the more sophisticated AO systems available today at large telescopes. A critical aspect for these WFAO systems in order to deliver an optimised performance is the knowledge of the vertical spatiotemporal distribution of the CN2 and the wind speed. Previous studies (Cortes et al., 2012) already proved the ability of GeMS (the Gemini Multi-Conjugated AO system) in retrieving CN2 and wind vertical stratification using the telemetry data. To assess the reliability of the GeMS wind speed estimates a preliminary study (Neichel et al., 2014) compared wind speed retrieved from GeMS with that obtained with the atmospherical model Meso-Nh on a small sample of nights providing promising results. The latter technique is very reliable for the wind speed vertical stratification. The model outputs gave, indeed, an excellent agreement with a large sample of radiosoundings (~ 50) both in statistical terms and on individual flights (Masciadri et al., 2013). Such a tool can t...

  3. Effect of Frailty on Functional Gain, Resource Utilisation, and Discharge Destination: An Observational Prospective Study in a GEM Ward

    Directory of Open Access Journals (Sweden)

    Sujatha Kawryshanker

    2014-01-01

    Full Text Available Background. A geriatric evaluation and management unit (GEM manages elderly inpatients with functional impairments. There is a paucity of literature on frailty and whether this impacts on rehabilitation outcomes. Objectives. To examine frailty score (FS as a predictor of functional gain, resource utilisation, and destinations for GEM patients. Methods. A single centre prospective case study design. Participants (n=136 were ≥65 years old and admitted to a tertiary hospital GEM. Five patients were excluded by the preset exclusion criteria, that is, medically unstable, severe dementia or communication difficulties after stroke. Core data included demographics, frailty score (FS, and functional independence. Results. The mean functional improvement (FIM from admission to discharge was 11.26 (95% CI 8.87, 13.66; P<0.001. Discharge FIM was positively correlated with admission FIM (β=0.748; P<0.001 and negatively correlated with frailty score (β=−1.151; P=0.014. The majority of the patients were in the “frail” group. “Frail” and “severely frail” subgroups improved more on mean FIM scores at discharge, relative to that experienced by the “pre-frail” group. Conclusion. All patients experienced functional improvement. Frailer patients improved more on their FIM and improved relatively more than their prefrail counterparts. Higher frailty correlated with reduced independence and greater resource utilisation. This study demonstrates that FS could be a prognostic indicator of physical independence and resource utilisation.

  4. Performance of a large size triple GEM detector at high particle rate for CBM Experiment at FAIR

    CERN Document Server

    Adak, Rama Prasad; Dubey, A K; Samanta, Subhasis; Saini, J; Das, S; Raha, S; Chattopadhyay, Subhasis

    2016-01-01

    In CBM experiment dimuon will be detected by a Muon Chamber (MUCH) consisting of segmented absorbers of varying widths and of tracking chambers sandwiched between the absorber-pairs. In this fixed target experiment operating at the highest interaction rate of $~10~MHz$, the first tracking chamber in its inner radial ring will face a particle rate of $400 kHz/cm^2$. To operate at such a high particle density, GEM technology based detectors have been chosen for the first two stations of MUCH. We have reported earlier the performance of several small-size GEM detector prototypes built at VECC for use in MUCH. A real-size GEM prototype has been tested using proton beam of momentum $2.36 ~GeV/c$ at COSY- Juelich, Germany. The detector was read out using nXYTER ASIC operated in self-triggering mode. An efficiency of the detector higher than $96\\%$ has been achieved. Variation of efficiency with the rate of incoming protons when tested at the highest rate of 1.5 MHz/cm$^2$ has been found to vary within $~2\\%$. The g...

  5. The Evolutionary Behavior of Old Novae in their Quiescent Stage: DN Gem, T Aur and HR Lyr

    Science.gov (United States)

    Findlay, Amanda M.; Gropp, Jeffrey; Hause, Connor; Sion, Edward M.

    2016-01-01

    There is currently a poor understanding about how a nova explosion affects the rate of mass transfer in a cataclysmic binary system and the subsequent evolutionary behavior of the accreting white dwarf during post-nova quiescence. In order to shed light on this fundamental question, we have carried out a synthetic spectral analysis of the archival HST and IUE far ultraviolet spectra of the post-novae, DN Gem (Nova Gem 1912), T Aur (Nova Aur 1891) and HR Lyrae (Nova Lyr 1919). We have utilized the best available input parameters from the literature for the white dwarf masses, orbital inclinations and distances of each system while adopting the newly determined interstellar reddening corrections, E(B-V), of Selvelli and Gilmozzi (2013). Our synthetic spectral analysis utilized optically thick, steady state accretion disk models and white dwarf model atmospheres that we constructed using TLUSTY and SYNSPEC (Hubeny 1988, Hubeny and Lanz 1995). We report the results of our model fitting including the mass transfer rates and other physical properties 115 years (DN Gem), 124 years (T Aur) and 96 years (HR Lyra) after their respective nova explosions.This work is supported by NASA grants NNX13AF12G to Villanova University and a summerundergraduate research assistantship from the NASA-DSGC.

  6. Construction and Performance of Large-Area Triple-GEM Prototypes for Future Upgrades of the CMS Forward Muon System

    CERN Document Server

    Tytgat, M; Zaganidis, N.; Ban, Y.; Cai, J.; Teng, H.; Mohapatra, A.; Moulik, T.; Abbrescia, M.; Colaleo, A.; de Robertis, G.; Loddo, F.; Maggi, M.; Nuzzo, S.; Tupputi, S.A.; Benussi, L.; Bianco, S.; Colafranceschi, S.; Piccolo, D.; Raffone, G.; Saviano, G.; Bagliesi, M.G.; Cecchi, R.; Magazzu, G.; Oliveri, E.; Turini, N.; Fruboes, T.; Abbaneo, D.; Armagnaud, C.; Aspell, P.; Bally, S.; Berzano, U.; Bos, J.; Bunkowski, K.; Chatelain, J.P.; Christiansen, J.; Conde Garcia, A.; David, E.; De Oliveira, R.; Duarte Pinto, S.; Ferry, S.; Formenti, F.; Franconi, L.; Marchioro, A.; Mehta, K.; Merlin, J.; Nemallapudi, M.V.; Postema, H.; Rodrigues, A.; Ropelewski, L.; Sharma, A.; Smilkjovic, N.; Villa, M.; Zientek, M.; Gutierrez, A.; Karchin, P.E.; Gnanvo, K.; Hohlmann, M.; Staib, M.J.

    2011-01-01

    At present, part of the forward RPC muon system of the CMS detector at the CERN LHC remains uninstrumented in the high-\\eta region. An international collaboration is investigating the possibility of covering the 1.6 < |\\eta| < 2.4 region of the muon endcaps with large-area triple-GEM detectors. Given their good spatial resolution, high rate capability, and radiation hardness, these micro-pattern gas detectors are an appealing option for simultaneously enhancing muon tracking and triggering capabilities in a future upgrade of the CMS detector. A general overview of this feasibility study will be presented. The design and construction of small (10\\times10 cm2) and full-size trapezoidal (1\\times0.5 m2) triple-GEM prototypes will be described. During detector assembly, different techniques for stretching the GEM foils were tested. Results from measurements with x-rays and from test beam campaigns at the CERN SPS will be shown for the small and large prototypes. Preliminary simulation studies on the expected...

  7. Star in Deep Freeze Chills Theory, MIT Researchers Report

    Science.gov (United States)

    2001-09-01

    CAMBRIDGE, Mass. -- Like a frozen turkey that just won't thaw, a strange star near the center of the Milky Way is surprising MIT experts and colleagues with its remarkably low temperature. The odd behavior is chilling current theories of stellar physics. A famously battered neutron star named KS 1731-260 appears no hotter than some of its tranquil brethren, despite enduring the heat of constant thermonuclear explosions with the force of billions of hydrogen bombs every second across a region only a few miles wide for the past 12 years. Dr. Rudi Wijnands, an astrophysicist at MIT's Center for Space Research, used the Chandra X-ray Observatory to measure the temperature of the neutron star at a very opportune moment, only months after the nuclear war apparently ended and the smoke cleared. He presented his team's findings September 5 in Washington, D.C. at a scientific conference entitled "Two Years of Science with Chandra." "Twelve years of constant thermonuclear explosions: One would think that would heat things up," said Wijnands. "This leaves us wondering whether some neutron stars are in the freezer for a much longer time than previously thought and consequently take a long time to heat up, or whether they cool down incredibly fast. Either explanation has profound implications for our field." Neutron stars are the dense, core remains of stars once many times more massive than our Sun. They are created in dazzling supernovas, in which the outer shell of the star explodes into space, and the core, containing about as much mass as the Sun, implodes and collapses into a sphere no wider than Cambridge, Massachusetts. Despite their tiny size, neutron stars are visible in several ways. One is through accretion. Neutron stars are a strong source of gravity. When they exist in binary star systems, such as KS 1731-260, they can attract the gas from what is often a "healthy" hydrogen-burning companion star (although the nature of KS 1731-260's companion is not clear.) Gas

  8. Entwicklung und Charakterisierung eines Prozesses zur thermischen Atomlagenabscheidung von Ruthenium mit in-situ Messtechnik

    OpenAIRE

    Junige, Marcel

    2011-01-01

    Ruthenium und sein elektrisch leitfähiges Rutheniumdioxid sind viel versprechende Kandidaten als Elektrodenmaterial in MIM (Metall-Isolator-Metall-)Kondensatoren mit Dielektrika hoher Permittivität der nächsten Generation von DRAM-Speichern, als Metall-Gate-Elektroden in p-Kanal-MOS-Transistoren mit Dielektrika hoher Permittivität, oder als Keimschicht für das direkte elektrochemische Abscheiden von Kupfer-Verbindungsleitungen. Die ALD (Atomic Layer Deposition) wächst Materiallagen mit wen...

  9. GEM-based TPC with CCD Imaging for Directional Dark Matter Detection

    CERN Document Server

    Phan, N S; Lee, E R; Loomba, D; Matthews, J A J; Miller, E H

    2015-01-01

    Directional dark matter detection will require scale-ups to large volumes if low-pressure gas Time Projection Chambers (TPCs) are the only viable technology. We discuss some of the challenges for this technology, where balancing the goal of achieving the best sensitivity with that of cost effective scale-up requires an optimization over a large parameter space. Critical for this are the precision measurements of the fundamental properties of both electron and nuclear recoil tracks down to the lowest energies. Such measurements would provide a benchmark for background discrimination and directional sensitivity that could be used for future optimization studies for directional dark matter experiments. In this paper we describe a small, high resolution, high signal-to-noise GEM-based TPC with a 2D CCD readout designed for this goal. The performance of the detector was characterized using X-rays, gamma-rays, and neutrons, enabling detailed measurements of electron and nuclear recoil tracks. Stable effective gas g...

  10. Vanadium-rich ruby and sapphire within Mogok Gemfield, Myanmar: implications for gem color and genesis

    Science.gov (United States)

    Zaw, Khin; Sutherland, Lin; Yui, Tzen-Fu; Meffre, Sebastien; Thu, Kyaw

    2015-01-01

    Rubies and sapphires are of both scientific and commercial interest. These gemstones are corundum colored by transition elements within the alumina crystal lattice: Cr3+ yields red in ruby and Fe2+, Fe3+, and Ti4+ ionic interactions color sapphires. A minor ion, V3+ induces slate to purple colors and color change in some sapphires, but its role in coloring rubies remains enigmatic. Trace element and oxygen isotope composition provide genetic signatures for natural corundum and assist geographic typing. Here, we show that V can dominate chromophore contents in Mogok ruby suites. This raises implications for their color quality, enhancement treatments, geographic origin, exploration and exploitation and their comparison with rubies elsewhere. Precise LA-ICP-MS analysis of ruby and sapphire from Mogok placer and in situ deposits reveal that V can exceed 5,000 ppm, giving V/Cr, V/Fe and V/Ti ratios up to 26, 78, and 97 respectively. Such values significantly exceed those found elsewhere suggesting a localized geological control on V-rich ruby distribution. Our results demonstrate that detailed geochemical studies of ruby suites reveal that V is a potential ruby tracer, encourage comparisons of V/Cr-variation between ruby suites and widen the scope for geographic typing and genesis of ruby. This will allow more precise comparison of Asian and other ruby fields and assist confirmation of Mogok sources for rubies in historical and contemporary gems and jewelry.

  11. Raman microspectrometry, FT-IR and inclusion characteristics of gem garnets from Tanzania and Madagascar

    Institute of Scientific and Technical Information of China (English)

    Sang-kon Kim; Maeng-eon Park; Seung-gyun Baek; Kyu-youl Sung; Sun-ok Kim; Hee-yul Park

    2004-01-01

    Chemical composition, Raman microspectrometry, and Fourier transform infrared (FT-IR) and SEM-CL (Cathodluminescence) analyses are carried out for Tanzania and Madagascar garnets for locality identification. Inclusion study was sustained after electron probe microanalysis (EPMA). Needle-like illmenites, apatites and zircons were the most common solid inclusions in Tanzania garnets. Madagascar garnets revealed rutile needles and apatites were also observed, but differences in size, shape and distribution patterns were noticed compared to Tanzania garnets. Tanzania garnets exhibited all types of observable fluid inclusions such as "fingerprint" pattern, called Type Ⅰ-A, liquid-only (L) single phase fluid inclusion, called Type Ⅰ-B and Type Ⅱ-A (L + S), Type Ⅱ-B (L + V) and Type Ⅲ-A (L + Sylvite +S), Type Ⅲ-B (L+S+V), while no more than two phase fluid inclusions found in both Madagascar and Korea garnets even if all examined garnets from three localities retained "fingerprint" features, so called, partially healed fractures, in common. Chemical composition, Raman microspectrometry and Fourier transform infrared (FT-IR) analysis taken turned out to be useful methods for the purpose of this study. Using consequences of SEM-CL and inclusion study, accordingly,the locality identification of gem-quality garnets is capable of being available in further application for other kinds of gemstones.

  12. Study of reconstruction methods for a time projection chamber with GEM gas amplification system

    International Nuclear Information System (INIS)

    A new e+e- linear collider with an energy range up to 1TeV is planned in an international collaboration: the International Linear Collider (ILC). This collider will be able to do precision measurements of the Higgs particle and of physics beyond the Standard Model. In the Large Detector Concept (LDC) - which is one proposal for a detector at the ILC - a Time Projection Chamber (TPC) is foreseen as the main tracking device. To meet the requirements on the resolution and to be able to work in the environment at the ILC, the application of new gas amplification technologies in the TPC is necessary. One option is an amplification system based on Gas Electron Multipliers (GEMs). Due to the - in comparison with older technologies - small spatial width of the signals, this technology poses new requirements on the readout structures and the reconstruction methods. In this work, the performance and the systematics of different reconstruction methods have been studied, based on data measured with a TPC prototype in high magnetic fields of up to 4T and data from a Monte Carlo simulation. The latest results of the achievable point resolution are presented and their limitations have been investigated. (orig.)

  13. Effects from switching on PIC simulations: Geospace Environmental Modeling (GEM) reconnection setup revisited

    Science.gov (United States)

    Bourdin, P. A.; Nakamura, T.; Narita, Y.

    2015-12-01

    Electromagnetic Parcile-In-Cell (PIC) simulations are widely used to study plasma phenomena where kinetic scales are coupled to fluid scales. One of these phenomena is the evolution of magnetic reconnection. Switch-on effects have been described earlier for magneto-/hydrodynamic (MHD and HD) simulations, where oscillations are ignited by the initial condition and the usual instantaneous way of starting a simulation run. Here we revisit the GEM setup (a Harris current sheet) and demonstrate the immediate generation of oscillations propagating perpendicular to the magnetic shear layer (in Bz). Also we show how these oscillations do not dissipate quickly and will later be mode-converted to generate wave power, first in By, much later also in Bx (pointing along the shear direction). One needs to take care not to interpret these oscillations as physical wave modes associated with the nature of reconnection. We propose a method to prevent such switch-on effects from the beginning, that should be considered for implementation in other PIC simulation codes as well.

  14. Performance of a large-area GEM detector read out with wide radial zigzag strips

    Science.gov (United States)

    Zhang, Aiwu; Bhopatkar, Vallary; Hansen, Eric; Hohlmann, Marcus; Khanal, Shreeya; Phipps, Michael; Starling, Elizabeth; Twigger, Jessie; Walton, Kimberly

    2016-03-01

    A 1-meter-long trapezoidal Triple-GEM detector with wide readout strips was tested in hadron beams at the Fermilab Test Beam Facility in October 2013. The readout strips have a special zigzag geometry and run radially with an azimuthal pitch of 1.37 mrad to measure the azimuthal ϕ-coordinate of incident particles. The zigzag geometry of the readout reduces the required number of electronic channels by a factor of three compared to conventional straight readout strips while preserving good angular resolution. The average crosstalk between zigzag strips is measured to be an acceptable 5.5%. The detection efficiency of the detector is (98.4±0.2)%. When the non-linearity of the zigzag-strip response is corrected with track information, the angular resolution is measured to be (193±3) μrad, which corresponds to 14% of the angular strip pitch. Multiple Coulomb scattering effects are fully taken into account in the data analysis with the help of a stand-alone Geant4 simulation that estimates interpolated track errors.

  15. Performance of a Large-area GEM Detector Read Out with Wide Radial Zigzag Strip

    CERN Document Server

    Zhang, Aiwu; Hansen, Eric; Hohlmann, Marcus; Khanal, Shreeya; Phipps, Michael; Starling, Elizabeth; Twigger, Jessie; Walton, Kimberly

    2015-01-01

    A 1-meter-long trapezoidal Triple-GEM detector with wide readout strips was tested in hadron beams at the Fermilab Test Beam Facility in October 2013. The readout strips have a special zigzag geometry and run along the radial direction with an azimuthal pitch of 1.37 mrad to measure the azimuthal phi-coordinate of incident particles. The zigzag geometry of the readout reduces the required number of electronic channels by a factor of three compared to conventional straight readout strips while preserving good angular resolution. The average crosstalk between zigzag strips is measured to be an acceptable 5.5%. The detection efficiency of the detector is (98.4+-0.2)%. When the non-linearity of the zigzag-strip response is corrected with track information, the angular resolution is measured to be (193+-3) urad, which corresponds to 14% of the angular strip pitch. Multiple Coulomb scattering effects are fully taken into account in the data analysis with the help of a stand-alone Geant4 simulation that estimates in...

  16. Kepler Observations of V447 Lyr: an Eclipsing U Gem Cataclysmic Variable

    Science.gov (United States)

    Ramsay, Gavin; Cannizzo, John K.; Howell, Steve B.; Wood, Matt A.; Still, Martin; Barclay, Thomas; Smale, Alan

    2012-01-01

    We present the results of an analysis of Kepler data covering 1.5 yr of the dwarf nova V447 Lyr. We detect eclipses of the accretion disc by the mass donating secondary star every 3.74 h which is the binary orbital period. V447 Lyr is therefore the first dwarf nova in the Kepler field to show eclipses.We also detect five long outbursts and six short outbursts showing V447 Lyr is a U Gem-type dwarf nova. We show that the orbital phase of the mid-eclipse occurs earlier during outbursts compared to quiescence and that the width of the eclipse is greater during outburst. This suggests that the bright spot is more prominent during quiescence and that the disc is larger during outburst than quiescence. This is consistent with an expansion of the outer disc radius due to the presence of high viscosity material associated with the outburst, followed by a contraction in quiescence due to the accretion of low angular momentum material. We note that the long outbursts appear to be triggered by a short outburst, which is also observed in the super-outbursts of SU UMa dwarf novae as observed using Kepler.

  17. Emissions from Petrol Engine Fueled Gasoline–Ethanol–Methanol (GEM Ternary mixture as Alternative Fuel

    Directory of Open Access Journals (Sweden)

    Thangavelu Saravana Kannan

    2015-01-01

    Full Text Available The increasing demands of petroleum fuels due to the rapid development automotive society coupled with the environmental pollution issues have inspired the efforts on exploring alternative fuels for internal combustion engines. Bioethanol obtained from biomass and bioenergy crops has been proclaimed as one of the feasible alternative to gasoline. In this study, the effect of gasoline–ethanol–methanol (GEM ternary blend on the emission characteristics of petrol engine was studied. Three different fuel blends, namely, E0 (gasoline, G75E21M4 (75% gasoline, 21% hydrous ethanol and 4% methanol and E25 (25% anhydrous ethanol and 75% gasoline were tested in a 1.3-l K3-VE spark-ignition engine. The results indicate that, when G75E21M4 fuel blend was used, a significant drop in CO, CO2, NOx and HC emissions by about 42%, 15%, 7% and 5.2% compared to E0, respectively. Moreover, the emission results for G75E21M4 are marginally lower than E25 whereas; HC emission was slightly higher than E25.

  18. Antimicrobial Activity of Hydroxylactone obtained by Biotransformation of Bromo- and Iodolactone with Gem-Dimethylcyclohexane Ring

    Energy Technology Data Exchange (ETDEWEB)

    Grabarczyk, Malgorzata; Maczka, Wanda; Winska, Katarzyna; Aniol, Miroslaw, E-mail: magrab@onet.pl [Department of Chemistry, Wroclaw University of Environmental and Life Sciences, Wroclaw (Poland); Zarowska, Barbara [Department of Biotechnology and Food Microbiology, Wroclaw University of Environmental and Life Sciences, Wroclaw (Poland)

    2013-12-01

    Two bicyclic lactones with gem-dimethylcyclohexane rings ({delta}-bromo-{gamma}-lactone and {delta}-iodo-{gamma}-lactone) were used as substrates for biotransformation by whole cells of several fungal strains (five cepas Fusarium, Nigrospora oryzae, Syncephalastrum racemosum, Stemphylium botryosum, Cunninghamella japonica and Acremonium sp). Some of the selected microorganisms (mainly Fusarium strains) transformed these lactones by hydrolytic dehalogenation into cis-(-)-2-hydroxy-4,4-dimethyl-9-oxabicyclo[4.3.0]nonan-8-one. The conversion of the substrate was equal or close to 100%, showing that this method allows for the complete removal of the halogen atom from the molecule, replacing it by a hydroxy group. The structures of all substrates and products were established on the basis of their spectral data. Hydroxylactone obtained as http://jbcs.sbq.org.br/audiencia{sub p}df.asp?aid2=3794&nomeArquivo=v24n12a05.pdf a result of biotransformation was examined for its biological activity against bacteria, yeasts and fungi. This compound inhibits the growth of some tested microorganisms. (author)

  19. GeMS MCAO observations of the Galactic globular cluster NGC 2808: the absolute age

    CERN Document Server

    Massari, Davide; McConnachie, A; Bono, G; Dall'Ora, M; Ferraro, I; Iannicola, G; Stetson, P B; Turri, P; Tolstoy, E

    2016-01-01

    Globular clusters are the oldest stellar systems in the Milky Way and probe the early epoch of the Galaxy formation. However, the uncertainties on their absolute age are still too large to soundly constrain how the Galactic structures have assembled. The aim of this work is to obtain an accurate estimate of the absolute age of the globular cluster NGC 2808 using deep IR data obtained with the multi conjugate adaptive optics system operating at the Gemini South telescope (GeMS). This exquisite photometry, combined with that obtained in V and I bands with HST, allowed us the detection of the faint Main Sequence Knee feature in NGC 2808 colour magnitude diagram. The difference between this point and the main sequence turn off is a good age estimator and provides ages with unprecedented accuracy. We found that NGC 2808 has an age of t=10.9\\pm0.7 (intrinsic) \\pm0.45 (metallicity term) Gyr. A possible contamination by He-enhanced population could make the cluster up to 0.25 Gyr older. Although this age estimate agr...

  20. Study of reconstruction methods for a time projection chamber with GEM gas amplification system

    Energy Technology Data Exchange (ETDEWEB)

    Diener, R.

    2006-12-15

    A new e{sup +}e{sup -} linear collider with an energy range up to 1TeV is planned in an international collaboration: the International Linear Collider (ILC). This collider will be able to do precision measurements of the Higgs particle and of physics beyond the Standard Model. In the Large Detector Concept (LDC) - which is one proposal for a detector at the ILC - a Time Projection Chamber (TPC) is foreseen as the main tracking device. To meet the requirements on the resolution and to be able to work in the environment at the ILC, the application of new gas amplification technologies in the TPC is necessary. One option is an amplification system based on Gas Electron Multipliers (GEMs). Due to the - in comparison with older technologies - small spatial width of the signals, this technology poses new requirements on the readout structures and the reconstruction methods. In this work, the performance and the systematics of different reconstruction methods have been studied, based on data measured with a TPC prototype in high magnetic fields of up to 4T and data from a Monte Carlo simulation. The latest results of the achievable point resolution are presented and their limitations have been investigated. (orig.)

  1. A new front-end ASIC for GEM detectors with time and charge measurement capabilities

    Science.gov (United States)

    Ciciriello, F.; Corsi, F.; De Robertis, G.; Felici, G.; Loddo, F.; Marzocca, C.; Matarrese, G.; Ranieri, A.

    2016-07-01

    A 32 channel CMOS front-end ASIC has been designed to read out the GEM detectors intended to be used for beam monitoring in a new proton-therapy facility currently under construction. In order to improve the spatial resolution by exploiting charge centroid algorithms, the analog channels, based on the classic CSA+shaper architecture, are equipped with a peak detector (PD) which works as an analog memory during the read-out phase. The outputs of the PDs are multiplexed towards an integrated 8-bit subranging ADC. An accurate trigger signal marks the arrival of a valid event and is generated by fast-ORing the outputs of 32 voltage discriminators which compare the shaper outputs with a programmable threshold. The digital part of the ASIC manages the read-out of the channels, the A/D conversion and the configuration of the ASIC. A 100 Mbit/s LVDS serial link is used for data communication. The sensitivity of the analog channel is 15 mV/fC and the dynamic range is 80 fC. The simulated ENC is about 650 e- for a detector capacitance of 10 pF. © 2001 Elsevier Science. All rights reserved

  2. First performance of the GeMS + GMOS system - 1. Imaging

    Science.gov (United States)

    Hibon, Pascale; Garrel, Vincent; Neichel, Benoit; Prout, Benjamin; Rigaut, Francois; Koning, Alice; Carrasco, Eleazar R.; Gimeno, German; Pessev, Peter

    2016-09-01

    During the commissioning of the Gemini MCAO System (GeMS), we had the opportunity to obtain data with the Gemini Multi-Object Spectrograph (GMOS), the most utilized instrument at Gemini South Observatory, in 2012 March and May. Several globular clusters were observed in imaging mode that allowed us to study the performance of this new and untested combination. GMOS is a visible instrument, hence pushing MCAO towards the visible. We report here on the results with the GMOS instruments, derive photometric performance in term of full width at half-maximum (FWHM) and throughput. In most of the cases, we obtained an improvement factor of at least 2 against the natural seeing. This result also depends on the natural guide star constellation selected for the observations and we then study the impact of the guide star selection on the FWHM performance. We also derive a first astrometric analysis showing that the GeMS+GMOS system provide an absolute astrometric precision better than 8 mas and a relative astrometric precision lower than 50 mas.

  3. Synthesis and applications of gem-bis-phosphonates, powerful complexing agents of metals

    International Nuclear Information System (INIS)

    This thesis was devoted to the development of new ways to prepare gem-bis-phosphonates compounds (BPs), and was carried out under the Program of Nuclear and Environmental Toxicology (ToxNuc-E). Two applications of these compounds have been investigated, the preparation of potent ligands of the uranyl ion for a target of decorporation, and the preparation of new anticancer compounds. The first of these applications was the consequence of work done in the laboratory, that have shown the strong uranium-binding properties of bis-phosphonic ligands. The in vivo tests performed on these compounds have shown the tendency of these ligands to cause liver accumulation of uranium, we wanted to address this problem by modifying the method of anchoring of the bis-phosphonates functions. To this end we have developed a new way to access to these compounds using a metal-carbenoid mediated poly-ols and poly-amines insertion, the metal-carbenoid species bearing the bis-phosphonate function. Regarding the preparation of BPs as anticancer agents, we have developed a new synthetic pathway using a phosphine catalyzed α-P addition of phosphorated pro-nucleophiles to alkynyl-phosphonates as a key step. This enabled us to prepare thirty compound whose activity was evaluated on two cell lines (A431 and HuH7). Five of these compounds possess an activity equivalent to that of the compound described as the most active, the Zoledronate. (author)

  4. Multichannel reconfigurable measurement system for hot plasma diagnostics based on GEM-2D detector

    Science.gov (United States)

    Wojenski, A. J.; Kasprowicz, G.; Pozniak, K. T.; Byszuk, A.; Chernyshova, M.; Czarski, T.; Jablonski, S.; Juszczyk, B.; Zienkiewicz, P.

    2015-12-01

    In the future magnetically confined fusion research reactors (e.g. ITER tokamak), precise determination of the level of the soft X-ray radiation of plasma with temperature above 30 keV (around 350 mln K) will be very important in plasma parameters optimization. This paper presents the first version of a designed spectrography measurement system. The system is already installed at JET tokamak. Based on the experience gained from the project, the new generation of hardware for spectrography measurements, was designed and also described in the paper. The GEM detector readout structure was changed to 2D in order to perform measurements of i.e. laser generated plasma. The hardware structure of the system was redesigned in order to provide large number of high speed input channels. Finally, this paper also covers the issue of new control software, necessary to set-up a complete system of certain complexity and perform data acquisition. The main goal of the project was to develop a new version of the system, which includes upgraded structure and data transmission infrastructure (i.e. handling large number of measurement channels, high sampling rate).

  5. PLC-controlled cryostats for the BlackGEM and MeerLICHT detectors

    CERN Document Server

    Raskin, Gert; Pessemier, Wim; Bloemen, Steven; Klein-Wolt, Marc; Roelfsema, Ronald; Groot, Paul; Aerts, Conny

    2016-01-01

    BlackGEM (BG) is an array of telescopes, currently under development at the Radboud University Nijmegen and at NOVA. It targets the detection of the optical counterparts of gravitational waves. The first 3 BG telescopes are planned to be installed in 2018 at the La Silla observatory. A single prototype telescope, named MeerLICHT, will already be commissioned early 2017 in Sutherland to provide an optical complement for the MeerKAT radio array. The BG array consists of, initially, a set of 3 robotic 65-cm wide-field telescopes. Each telescope is equipped with a single STA1600 CCD detector with 10.5k x 10.5k 9-mum pixels that covers a 2.7 square degrees field of view. The cryostats for housing these detectors are developed and built at the KU Leuven University. The operational model of BG requires long periods of reliable ands-off operation. Therefore, we designed the cryostats for long vacuum hold time and we make use of a closed-cycle cooling system, based on Polycold PCC Joule-Thomson coolers. A single progr...

  6. The GEM detectors for the innermost region of the forward muon station of the LHCb experiment

    CERN Document Server

    Alfonsi, M

    The LHCb experiment will take place at the LHC accelerator at CERN and will start in 2008. It is dedicated to precision measurements of CP violation and rare decays in the b quark sec- tor. The apparatus is a single arm spectrometer and it is designed with a robust and flexible trigger in order to extensively gain access to a wide spread of differ ent physical processes involving beauty particles. This will allow to over-constrain the Standard M odel predictions about CP violation, and to discover any possible inconsistency, whi ch would reveal the presence of “New Physics” beyond the Standard Model. This thesis reports the work performed on two aspects of the L HCb experiment: the main contribution is the development and the construction of a de tector based on Gas Electron Multiplier (GEM) technology for the instrumentation of the high irradiated region around the beam pipe of the forward Muon Station; in the second part t he possibility of the search of the rare D 0 → + − decay at the LHCb exper...

  7. Anwendungsbeobachtungen mit Zolmitriptan-Rapilmet in der Praxis

    Directory of Open Access Journals (Sweden)

    Wessely P

    2004-01-01

    Full Text Available Nach Darstellungen der Prinzipien der evidenzbasierten Therapie (EBM der Migräneattacken wird die besondere Bedeutung der Triptane hervorgehoben. Die Entscheidung, Triptane einzusetzen, wird nicht unter Anwendung einer starren stufenweisen Verordnung, sondern flexibel anhand von Entscheidungshilfen für eine stratifizierte Therapieplanung getroffen. Eine solche Hilfe ist z. B. der in den USA entwickelte MIDAS-Fragebogen, der übersichtlich und einfach den Gesamtkomplex der Migräne erfaßt und nicht nur den Kopfschmerz, sondern auch die begleitenden autonomen Phänomene und vor allem auch die Beeinträchtigungen im sozio-ökonomischen Formenkreis bewertet. Dadurch kann die individuell erforderliche Therapieintensität, also z. B. der Einsatz von Triptanen, einfacher abgeschätzt werden. Die vorliegende Studie ist eine offene Anwendungsbeobachtung von Zolmitriptan-Rapimelt bei 349 Migränepatienten unter Verwendung des MIDAS-Fragebogens. Nach dreimonatiger Therapie konnte eine globale Besserung im Bereich der MIDAS-Scores nachgewiesen werden, wobei der Schweregrad IV von 42,7 % auf 14,6 % abgenommen hat (insgesamt signifikant für die Verbesserung jeweils um einen MIDAS-Grad. Die Kopfschmerzfrequenz hat sich ebenfalls von 14,6 Kopfschmerztage auf 8,7 reduziert, ebenso die Intensität – gemessen auf einer VAS-Skala – von 7,3 auf 5,3. Die Nebenwirkungsrate lag unter 2 %, die subjektive Zufriedenheit mit der Gesamtwirksamkeit von Zolmitriptan-Lyotabletten wurde in der Beurteilung durch die Probanden von 49,9 % mit sehr gut und von 35,8 % als gut bewertet, lediglich 4,3 % befanden die Medikation als unzureichend. In der Behandlung von Migräneattacken läßt sich für Zolmitriptan-RM eine hohe Patientenakzeptanz und auch ein hohes Maß an Effektivität und Wirkkonsistenz nicht nur unter den strengen Kriterien einer klinischen Prüfung, sondern auch unter den Bedingungen der Alltagspraxis nachweisen.

  8. Dexamethason-21-isonicotinat als Begleittherapie bei Kühen mit Systemic Inflammatory Response Syndrome

    OpenAIRE

    Pevec, Till

    2007-01-01

    Dexamethason-21-isonicotinat als Begleittherapie bei Kühen mit Systemic Inflammatory Response Syndrome Schlüsselwörter: Dexamethason, SIRS, Phagozytoseaktivität/Burstaktivität von Monozyten und neutrophilen Granulozyten, Tumornekrose Faktor alpha

  9. Lessons learned from the MIT Tara control and data system

    International Nuclear Information System (INIS)

    The control and data system of the MIT Tara Tandem Mirror has worked successfully throughout the lifetime of the experiment (1983 through 1987). As the Tara project winds down, it is appropriate to summarize the lessons learned from the implementation and operation of the control and data system over the years and in its final form. The control system handled ∼2400 I/0 points in real time throughout the 5 to 10 minute shot cycle while the data system, in near real time, handled ∼1000 signals with a total of 5 to 7 Mbytes of data each shot. The implementation depended upon a consistent approach based on separating physics and engineering functions and on detailed functional diagrams with narrowly defined cross communication. This paper is a comprehensive treatment of the principal successes, residual problems, and dilemmas that arose from the beginning until the final hardware and software implementation. Suggestions for future systems of either similar size or of larger scale such as CIT are made in the conclusion. 11 refs., 1 fig

  10. Diagnostische und therapeutische Optionen bei Patientinnen mit Myomen: Myomembolisation

    Directory of Open Access Journals (Sweden)

    Bohlmann MK

    2014-01-01

    Full Text Available iHintergrund:/i Symptomatische Uterusmyome stellen einen häufigen und bedeutsamen Morbiditätsgrund für Frauen in der reproduktiven Lebensphase dar. Aufgrund bis dato eingeschränkter konservativer Therapieoptionen erfolgten zur Symptomkontrolle operative Interventionen, wobei in einem hohen Prozentsatz Hysterektomien erfolgten. Mit der Methode der kathetergestützten Myomembolisation steht seit einiger Zeit eine nicht-invasive Alternative zur Myombehandlung zur Verfügung. iMethoden:/i Im Rahmen dieser Übersicht werden Indikationen, Voraussetzungen, Durchführung, Nebenwirkungen und Outcome einer Embolisationsbehandlung dargestellt, wobei insbesondere auf fertilitätsrelevante Aspekte eingegangen wird. iErgebnis:/i Die Therapieform der Embolisation weist gute Erfolgsraten in Bezug auf eine Verbesserung der Hypermenorrhoe (etwa 85 % der Versuche auf, wohingegen myombedingte Verdrängungs- und Druckbeschwerden zu 30–60 % erfolgreich behandelt werden. Die ischämiebedingten Beschwerden im Rahmen einer Intervention bedürfen einer adäquaten Analgesie. iSchlussfolgerung:/i Die Behandlung mittels Embolisation kann in ausgewählten Fällen eine effektive und nicht-invasive Therapieoption bei symptomatischem Uterus myomatosus darstellen.

  11. Echtzeit-Ultraschallsimulation auf Grafik-Prozessoren mit CUDA

    Science.gov (United States)

    Reichl, Tobias; Passenger, Josh; Acosta, Oscar; Salvado, Olivier

    Trotz der zunehmenden Verbreitung jüngerer bildgebender Verfahren bleibt medizinischer Ultraschall (US) weiterhin ein wichtiges Hilfsmittel bei chirurgischen Eingriffen und der klinischen Diagnose. Viele US-gestützte medizinische Prozeduren erfordern allerdings ausgiebiges Training, so dass es wünschenswert ist, eine realistische Simulation von US-Bildern zur Verfügung zu stellen. Im Gegensatz zu früheren Ansätzen simulieren wir solche Bilder auf der "Graphics Processing Unit“. Wir erweitern hierzu eine Methode, die von Wein et al. für die Abschätzung von US-Reflexionen aus Daten der Computertomographie (CT) vorgeschlagen wurde, zu einer leichter zu berechnenden Form. Zusätzlich schätzen wir die US-Absorption aus den CT-Daten ab. Mit Hilfe von NVIDIAs "Compute Unified Device Architecture“ (CUDA) simulieren wir Reflexion, Verschattung, Rauschen und radiale Unschärfe, ausgehend von unbearbeiteten CT-Daten in Echtzeit und ohne Vorausberechnung.

  12. The structure of the GemC1 coiled coil and its interaction with the Geminin family of coiled-coil proteins

    Energy Technology Data Exchange (ETDEWEB)

    Caillat, Christophe; Fish, Alexander [The Netherlands Cancer Institute, 1066 CX Amsterdam (Netherlands); Pefani, Dafni-Eleftheria; Taraviras, Stavros; Lygerou, Zoi [University of Patras, 26505 Rio, Patras (Greece); Perrakis, Anastassis, E-mail: a.perrakis@nki.nl [The Netherlands Cancer Institute, 1066 CX Amsterdam (Netherlands)

    2015-10-31

    The GemC1 coiled-coil structure has subtle differences compared with its homologues Geminin and Idas. Co-expression experiments in cells and biophysical stability analysis of the Geminin-family coiled coils suggest that the GemC1 coiled coil alone is unstable. GemC1, together with Idas and Geminin, an important regulator of DNA-replication licensing and differentiation decisions, constitute a superfamily sharing a homologous central coiled-coil domain. To better understand this family of proteins, the crystal structure of a GemC1 coiled-coil domain variant engineered for better solubility was determined to 2.2 Å resolution. GemC1 shows a less typical coiled coil compared with the Geminin homodimer and the Geminin–Idas heterodimer structures. It is also shown that both in vitro and in cells GemC1 interacts with Geminin through its coiled-coil domain, forming a heterodimer that is more stable that the GemC1 homodimer. Comparative analysis of the thermal stability of all of the possible superfamily complexes, using circular dichroism to follow the unfolding of the entire helix of the coiled coil, or intrinsic tryptophan fluorescence of a unique conserved N-terminal tryptophan, shows that the unfolding of the coiled coil is likely to take place from the C-terminus towards the N-terminus. It is also shown that homodimers show a single-state unfolding, while heterodimers show a two-state unfolding, suggesting that the dimer first falls apart and the helices then unfold according to the stability of each protein. The findings argue that Geminin-family members form homodimers and heterodimers between them, and this ability is likely to be important for modulating their function in cycling and differentiating cells.

  13. Quellverhalten teilgesättigter bindiger Böden mit mittlerem Quellpotential

    OpenAIRE

    Dobrowolsky, Markus

    2008-01-01

    Die Arbeit beschäftigt sich mit der Bestimmung der Zwangsbeanspruchungen und mit den daraus resultierenden Verformungen auf geotechnische Bauwerke infolge Quellen von teilgesättigten, bindigen Böden. Zur Ermittlung eines Quellgesetzes zur Beschreibung dieses Volumenänderungsverhaltens wurden zwei spezielle Oedometergeräte entwickelt. Mittels eines modifizierten Oedometers können radiale und axiale Quelldrücke getrennt voneinander gemessen sowie axiale Dehnungen zugelassen werden. Die axialen ...

  14. Spätfolgen nach Stimmlippenaugmentation mit Teflon: Klinisches Bild und Rehabilitation

    OpenAIRE

    Reiter, R.; J. Veit; Brosch, S

    2012-01-01

    Hintergrund: Teflon wurde vor allem bis etwa 1990 zur Stimmlippenaugmentation bei einer einseitigen Stimmlippenparese eingesetzt. Aufgrund mehrerer Beobachtungen von Teflongranulomen bzw. Dislokation in Zusammenhang mit der Applikation im Larynx gilt die Substanz inzwischen als obsolet.Material und Methoden: Wir beschreiben mögliche Komplikationen, deren Diagnostik und Therapie bei 2 Patienten mit vorangegangener permanenter Stimmlippenaugmentation mittels Teflon.Ergebnisse: Ein 61-jährige...

  15. Interaktion von Betonstahl und textiler Bewehrung bei der Biegeverstärkung mit textilbewehrtem Beton

    OpenAIRE

    Weiland, Silvio

    2010-01-01

    Textilbewehrter Beton zur Verstärkung von Stahlbetonbauteilen ist neben den klassischen und etablierten Verfahren eine äußerst interessante Alternative, die die Vorteile der leichten Kohlenstofffaserklebeverstärkungen mit denen von Spritzbeton mit Bewehrung verbindet. Aus den theoretischen und experimentellen Untersuchungen in dieser Arbeit können wichtige Erkenntnisse zum gemeinsamen Tragverhalten von Betonstahl und textiler Bewehrung sowie zu den Auswirkungen der verbundbedingten Unterschie...

  16. Untersuchungen zum Zugtragverhalten hochduktiler Faserbetone mit zusätzlicher Textilbewehrung

    OpenAIRE

    Korb, Simone

    2010-01-01

    Hochduktiler Faserbeton zeigt ein dehnungsverfestigendes Zugtragverhalten mit ausgeprägter Vielfachrissbildung und einer Bruchdehnung von bis zu 5 %. Aufgrund der sehr kleinen Rissbreiten im Gebrauchszustand von weniger als 0,1 mm können hochduktile Faserbetone als quasi-wasserundurchlässig angesehen werden. Ausgehend von diesen Materialeigenschaften entstand die Überlegung, Fugen, z.B. zwischen Betonfertigteilen im Hochbau, mit einer Abdeckung aus hochduktilem Faserbeton zu überbrücken. Hier...

  17. Asymptotische Nahfeldanalysen ebener Multi-Materialverbindungsstellen mit der Methode komplexer Potentiale

    OpenAIRE

    Sator, Christian

    2010-01-01

    In der vorliegenden Arbeit werden die Nahfelder an ebenen Multi-Materialverbindungsstellen betrachtet, die aus Fügungen isotroper Sektoren bestehen und ausschließlich in ihrer Ebene belastet sind. Die asymptotischen Nahfeldanalysen erfolgen mit der Methode komplexer Potentiale mit einer geeigneten Kombination von Potenzfunktionen. Bei den Analysen steht insbesondere die Ermittlung der Singularitätsexponenten im Vordergrund. Die Arbeit leistet einige neue theoretische Beiträge: So wird ein Nac...

  18. Untersuchung innermotorischer Einflussgrößen auf die Partikelemission eines Ottomotors mit Direkteinspritzung

    OpenAIRE

    Dageförde, Helge

    2015-01-01

    Die Arbeit befasst sich mit der Ermittlung der Ursachen von Partikelemissionen und der Ableitung von Maßnahmen zu ihrer Reduktion. Dabei spielt die Betrachtung der Gemischbildung eine wesentliche Rolle. Es werden innermotorische optische Untersuchungen an einem Einhubtriebwerk sowie einem Einzylindermotor durchgeführt und mehrere Faktoren auf ihren Einfluss auf die Partikelbildung und -oxidation diskutiert. Die motorischen Untersuchungen werden mit Partikelmessungen im Abgas begleitet.

  19. Nichtinvasive Messung von Blutparameter mit Infrarot-Quantenkaskadenlaser und photoakustischer Detektion

    OpenAIRE

    Xhelaj, Arjan

    2009-01-01

    Diese Arbeit beschreibt wie mit physikalischen Methoden die Glukosekonzentration gemessen werden kann. Die Infrarot-Spektroskopie bietet eine Möglichkeit da die Energie der meisten Molekülschwingungen Photonenenergien im infraroten Spektralbereich entspricht. Hier zeigen Glukosemoleküle charakteristische Absorptionsspektren, die mit spektroskopischen Methoden gemessen werden. Um nicht invasiv zu messen, wurde eine photoakustische Messmethode gewählt. Die Grundidee ist, dass die durch Licht an...

  20. Untersuchung einer Axialgitterschaufel mit Höchstumlenkung durch Struktur- und niederfrequente Wölbungsvariation

    OpenAIRE

    Jarius, Marc

    2000-01-01

    In hydraulischen und thermischen Strömungsmaschinen werden zur Erzeugung eines Vordralls Vorleiträder mit Schaufeln variabler Staffelung eingesetzt. Diese Vorleiträder besitzen nur bei relativ kleinen Umlenkwinkeln relativ kleine Verluste und finden ihre Anwendung hauptsächlich in großen Kraftwerks-Kühl- wasserpumpen. Dieses Regelverfahren wird sowohl bei halbaxialen als auch bei axialen Kreiselpumpen eingesetzt. In diesem Projekt soll die Umströmung einer einzelnen Vorleitradschaufel mit var...

  1. Die "wîlsælde"-Disputation : zur Auseinandersetzung mit der Astrologie in der "Kaiserchronik"

    OpenAIRE

    Dunphy, Graeme

    2011-01-01

    Als Einschub in der mittelhochdeutschen "Kaiserchronik" bieten die drei Disputationen weitaus tiefer greifende philosophisch-theologische Betrachtungen als der übrige Erzähltext. Die "wîlsælde"-Disputation greift die Auseinandersetzung mit der Astrologie auf. Der vorliegende Aufsatz vergleicht dieses Streitgespräch mit seiner patristischen Vorlage, den pseudoklementinischen "Recognitiones", und erkäirt die Umgestaltung des Stoffes in der "Kaiserchronik" im Hinblick auf Unterschiede in den ast...

  2. Vorkommen von Bakterien im unteren Respirationstrakt und deren Antibiotikaresistenz bei Hunden mit respiratorischen Symptomen

    OpenAIRE

    Rheinwald, Markus

    2015-01-01

    Im Rahmen der vorliegenden Arbeit wurde das Vorkommen von Bakterien im unteren Respirationstrakt von Hunden mit Atemwegserkrankungen und deren Resistenzverhalten gegenüber klinisch relevanten Antibiotika untersucht. Hierfür wurden die Ergebnisse der bakteriologischen Untersuchungen und Resistenztests von 502 Proben von 493 Hunden retrospektiv ausgewertet, die im Zeitraum von 1989 bis 2011 an der Medizinischen Kleintierklinik der Ludwig-Maximilians-Universität München mit respiratorischen Symp...

  3. Amifostin in subkutaner Anwendung bei Patienten mit Kopf-Hals-Tumoren

    OpenAIRE

    Wilder, Daniel

    2006-01-01

    Hintergrund: Amifostin (Ethyol®), ein phosphorylierter Aminothioalkohol mit der chemischen Bezeichnung S-2[3-aminopropylamino]-ethyl-thiophosphorsäure, ist eine Substanz mit einem breiten zytoprotektiven Spektrum für die radio- und chemotherapeutisch induzierten Nebenwirkungen. Die Substanz fungiert dabei im Sinne einer Prodrug. Daraus wird, in Abhängigkeit von der alkalischen Phosphatase, der dephosphorylierte aktive Metaboliten WR-1065 gebildet. Dieser ist für die protektiven Wirkungen ...

  4. Entwicklung und Evaluation eines psychoedukativen Elterngruppen-Trainingsprogramms für Familien mit autistischen Kindern

    OpenAIRE

    Probst, Paul

    2003-01-01

    In der Einleitung wird das Konzept des "Psychoedukativen Elterntrainings" erläutert und ein Überblick über den Forschungsstand zum Thema "Elterntraining in Familien mit autistischen Kindern" gegeben. Ausgehend von dieser Analyse wurde ein psychoedukatives Eltern-Gruppentraining für Familien mit autistischen Kindern entwickelt und im Rahmen eines 3-Monate-Follow-up-Versuchsplans evaluiert. Die beiden Hauptziele des Trainingcurriculums waren "Vermittlung eines Konzepts über Wesen, Ursach...

  5. Entwicklung und Evaluation eines psychoedukativen Elterngruppen-Trainingsprogramms für Familien mit autistischen Kindern

    OpenAIRE

    Probst, Paul

    2003-01-01

    In der Einleitung wird das Konzept des „Psychoedukativen Elterntrainings“ erläutert und ein Überblick über den Forschungsstand zum Thema „Elterntraining in Familien mit autistischen Kindern“ gegeben. Ausgehend von dieser Analyse wurde ein psychoedukatives Eltern-Gruppentraining für Familien mit autistischen Kindern entwickelt und im Rahmen eines 3-Monate-Follow-up-Versuchsplans evaluiert. Die beiden Hauptziele des Trainingcurriculums waren „Vermittlung eines Konzepts über Wesen, Ursachen, Beh...

  6. Dieselmotorische Kraftstoffzerstäubung und Gemischbildung mit Common-Rail Einspritzsystemen

    OpenAIRE

    Ofner, Bernd

    2014-01-01

    Mit der PDA-Messtechnik sowie mit dem Mie-Streulicht- und dem Schlieren-/Schattenverfahren wurden die dieselmotorische Kraftstoffzerstäubung und Gemischbildung in Druckkammern und in einer schnellen Kompressionsmaschine untersucht. Die Arbeiten konzentrierten sich auf die zeitliche Strahlausbreitung, den Kegelwinkel, das Tropfenspektrum und die Sprayverdampfung, abhängig von Gasdichte, Einspritzdruck und Gastemperatur. Drosseleffekte am Nadelsitz können die Spraybildung stark beeinflussen, wo...

  7. Analyse und Bewertung von Parametern der Produktionsumwelt bei der Milchgewinnung mit automatischen Melksystemen (AMS)

    OpenAIRE

    Unrath, Jens

    2005-01-01

    Automatische Melksysteme (AMS) gelten als jüngste Innovation auf dem Gebiet der Melktechnik und weisen im Vergleich mit konventionellen Melkständen eine Reihe von Besonderheiten auf. Um die Kühe zum freiwilligen und regelmäßigen Besuch des Melksystems anzuhalten, sind optimale mikroklimatische Bedingungen in der Melkbox notwendig. Die Analyse der mikroklimatischen Bedingungen in AMS erfolgte in einem Betrieb mit zwei parallel arbeitenden AMS und 110 melkenden Kühen. Dabei wurden die Parameter...

  8. Sandwichelemente mit Deckschichten aus Hochleistungsbeton und einem Kern aus extrudiertem Polystyrol

    OpenAIRE

    Müller, Frank

    2015-01-01

    Sandwichelemente vereinen aufgrund des gezielten Einsatzes verschiedener Materialien und deren schichtartigen Aufbaus sehr gute Dämmeigenschaften und ein geringes Eigengewicht mit hoher Tragfähigkeit und Biegesteifigkeit. Sie werden daher seit Beginn der 1960er-Jahre sowohl im Metallleichtbau als auch im Stahlbetonmassivbau vielfältig eingesetzt. Im Rahmen der vorliegenden Arbeit wurden Sandwichelemente mit Deckschichten aus einem mikro- oder auch textilbewehrtem Hochleistungsbeton und einem ...

  9. Kognitive Dysphasie und Angst : linguistische Untersuchungen bei Patienten mit Epilepsie und Angsterkrankung

    OpenAIRE

    Schneider, Barbara

    2007-01-01

    In der vorliegenden Arbeit wird der Frage nachgegangen, wie sich hirnorganische Erkrankungen, die nicht die klassischen perisylvischen Sprachareale betreffen, auf sprachliche und sprachorganisierende Funktionen auswirken. Dazu wurde eine Gruppe von Patienten mit fokaler Epilepsie und Angstaura (n = 8) sowie eine Gruppe von Patienten mit Angsterkrankung (n = 8) linguistisch untersucht. Ziel war es zum einen, Kognitive Dysphasien als sekundäre Sprach- bzw. Kommunikationsstörungen infolge kognit...

  10. Bestimmung der Ionisationsenergie von Actinium und Ultraspurenanalyse von Plutonium mit resonanter Ionisationsmassenspektrometrie (RIMS)

    OpenAIRE

    Waldek, Achim Marcus

    2001-01-01

    ZusammenfassungDie Resonanzionisationsmassenspektrometrie (RIMS) verbindet hohe Elementselektivität mit guter Nachweiseffizienz. Aufgrund dieser Eigenschaften ist die Methode für Ultraspurenanalyse und Untersuchungen an seltenen oder schwer handhabbaren Elementen gut geeignet. Für RIMS werden neutrale Atome mit monochromatischem Laserlicht ein- oder mehrfach resonant auf energetisch hoch liegende Niveaus angeregt und anschließend durch einen weiteren Laserstrahl oder durch ein elektrisches Fe...

  11. Ziehen von Rohren aus Aluminiumlegierungen über einem Pendelziehdorn mit Ultraschall

    OpenAIRE

    Klubovic, Vladimir V.; Komlik, L. K.; Chrenov, O. V.

    1994-01-01

    Unter Einkopplung von longitudinalen Ultraschallschwingungen kann man beim Rohrziehen aus Aluminiumlegierungen über einem Pendelziehdorn die Ziehkraft um 25 - 32 % senken und gleichzeitig die logarithmische Formänderung beim Ziehen pro Durchgang steigern. Das Rohrziehen mit Ultraschall über einem fliegenden Dorn ist effektiver als das Vollprofilziehen. Die Anwendung von Ultraschallschwingungen mit großer Intensität ist eine notwendige Bedingung für eine effektive Senkung der Ziehkraft, besond...

  12. Abbildungsmethoden für die Brust mit einem 3D-Ultraschall-Computertomographen

    OpenAIRE

    Dapp, Robin

    2013-01-01

    In dieser Arbeit wird die Theorie, Implementierung und Evaluierung von Algorithmen der Ultraschall-Transmissionstomographie für den am KIT entwickelten Prototypen 3D-USCT II behandelt. Bisherige Arbeiten gehen von idealen Voraussetzungen aus, diese Arbeit befasst sich hingegen mit der Bildrekonstruktion rauschbehafteter Echtdaten, die in einer klinischen Pilotstudie aufgenommen wurden. Von drei Krebsfällen konnten mit den Methoden dieser Arbeit zwei eindeutig identifiziert werden.

  13. Einfluss von Nickel auf Herstellung und Eigenschaften von bainitischem Gusseisen mit Kugelgraphit

    OpenAIRE

    Moualla, Hadi

    2009-01-01

    Gerade in Hinblick auf die Kombination aus hervorragender Festigkeit, relativ guter Zähigkeit und Dauerfestigkeit sowie beachtlicher Verschleißbeständigkeit macht bainitisches Gusseisen mit Kugelgrafit und dabei besonders das ADI (Austempered Duktile Iron) durch sein ausferritisches Gefüge seine Vorteile gegenüber Gusseisenwerkstoffen insbesondere Gusseisen mit Kugelgraphit und auch Stahlguss deutlich. Die konventionelle Herstellung von ADI erfolgt über ein Austenitisieren und ein anschließen...

  14. Höchstfeste nichtrostende austenitische CrMn-Stähle mit (C+N)

    OpenAIRE

    Riedner, Sascha

    2010-01-01

    Nichtrostende austenitische Stähle erzielen in der Regel nur geringe Festigkeiten. Die effektivste Methode zur Festigkeitssteigerung bietet das Legieren mit interstitiellen Atomen. Das gemeinsame Legieren mit (C+N) resultiert in offen erschmelzbaren, hochfesten nichtrostenden Austentiten. Die neuentwickelten Stähle weisen eine sehr hohe Austenitstabilität, Festigkeit, Kaltverfestigung, Zähigkeit und Duktilität auf. Auch unter zyklischer Beanspruchung kann die hohe Festigkeit genut...

  15. Untersuchungen an neutronenbestrahlten Reaktordruckbehälterstählen mit Neutronen-Kleinwinkelstreuung

    OpenAIRE

    Ulbricht, Andreas

    2010-01-01

    In dieser Arbeit wurde die durch Bestrahlung mit schnellen Neutronen bedingte Materialalterung von Reaktordruckbehälterstählen untersucht. Das Probenmaterial umfasste unbestrahlte, bestrahlte und ausgeheilte RDB-Stähle russischer und westlicher Reaktoren sowie Eisenbasis-Modelllegierungen. Mittels Neutronen-Kleinwinkelstreuung ließen sich bestrahlungsinduzierte Leerstellen/Fremdatom-Cluster unterschiedlicher Zusammensetzung mit mittlerem Radius um 1.0 nm nachweisen. Ihr Volumenanteil steigt m...

  16. Vorblütebehandlungen mit Kaolin gegen den Gemeinen Birnenblattsauger (Cacopsylla pyri)

    OpenAIRE

    Daniel, Claudia; Wyss, Eric

    2008-01-01

    Der Gemeine Birnenblattsauger, Cacopsylla pyri (L.) (Homoptera: Psyllidae), ist ein wichtiger Schädling in der Birnenproduktion. Ende Februar beginnen die überwinternden Adulten mit der Eiablage. Zu Schäden, wie Ertragsverlusten und Fruchtverschmutzungen durch Honigtau, kommt es jedoch erst durch die zahlreichen Nymphen der dritten Generation. Die Bekämpfung erfolgt meist mit Insektizidbehandlungen gegen die Nymphen der ersten drei Generationen (BOVEY et al. 1979). Im ökologischen Anbau wird ...

  17. Laccase-katalysierte Dominoreaktionen von Brenzcatechinen und Hydrochinonen mit 1,3-Dicarbonylverbindungen

    OpenAIRE

    Hajdok, Szilvia

    2012-01-01

    In der vorliegenden Arbeit wurden neuartige Dominoreaktionen beschrieben, die auf Laccase-katalysierten Oxidation von Brenzcatechinen und Hydrochinonen zu den entsprechenden o- und p-Chinonen und sich daran anschließenden Umsetzungen mit 1,3-Dicarbonylen beruhen. Im ersten Teil dieser Dissertation wurde ein effizienter Zugang zu 3,4-Dihydro-7,8-dihydroxy-2H-dibenzofuran-1-onen entwickelt, der sich die Laccase-initiierte Dominoreaktion zwischen Cyclohexan-1,3-dionen und Brenzcatechinen mit...

  18. eine randomisierte Studie an 200 Patienten mit Prostatae kleiner 100 g und urodynamisch nachgewiesener Obstruktion

    OpenAIRE

    Ahyai, Sascha A.

    2006-01-01

    Ziele: Trotz ihrer signifikanten Morbidität stellt die transurethrale Resektion der Prostata (TURP) den gold standard dar für die instrumentelle Therapie der durch die benigne Prostatahyperplasie (BPH) bedingten Blasenauslassobstruktion. Mit dem Hochleistungs-Holmium: YAG Laser kann endoskopisch, in einer relativ blutungsarmen Weise, Prostatagewebe enukleiert werden. Wir verglichen die Technik der transurethralen Holmium-Laser-Enukleation der Prostata (HoLEP) mit der Standard-TURP bei der ope...

  19. Serologischer Verlauf bei einer Infektion mit T. pallidum innerhalb einer Hochrisikopopulation in Tansania, Ostafrika

    OpenAIRE

    Dechamps, Britta

    2005-01-01

    Diese Doktorarbeit entstand im Rahmen eines HIV-Projekt des Tropeninstitutes München in Tansania. Dabei wurden die serologischen Daten bei einer Infektion mit Syphilis innerhalb einer Gruppe von 600 Prostituierten ausgewertet. Das Problem des serologischen Nachweises von Syphilis ist, dass die verschiedenen Testverfahren nur jeweilig begrenzte Aussagekraft bezüglich Stadium und Aktivität der Krankheit haben. Das Ziel meiner Arbeit war daher, herauszufinden, ob mit den Informationen von Ig...

  20. Biomechanische Untersuchungsergebnisse über die verbesserte Verankerung von Pedikelschrauben mit resorbierbarem

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    Die Prim?rstabilit?t von Pedikelschrauben im Knochen h?ngt in hohem Masse von der Knochendichte ab. Die Augmentation mit Zement ist ein klinisch einsetzbares Verfahren, um die Schrauben-Verankerung im osteoporotischen Knochen zu verbessern.In dieser Studie wurde eine neuartiges resorbierbares Knochenersatzmaterial (α-BSMTM) für diese Augmentation benutzt. Biomechanische Testungen wurden in vitro bei 16 Lendwirbelkorpern (L3-L5) aus 6 Individuen(75,2±13,7 Jahre) durchgeführt. Vor der biomechanischen Testung wurde bei allen Pr?paraten die trabekul?re Knochendichte mittels pQCT gemessen und beide Pedikel mit USS-Pedikelschrauben (5,0 mm × 45 mm) besetzt, von welchen eine mit α-BSMTM augmentiert war. Beim axialen Auszugstest wurden die maximale axiale Auszugskraft (F-max) sowie die Energieaufnahme bestimmt. Der Medianwert der F-max stieg beim Auszugstest durch die Zementierung mit α-BSMTM um 80 % von 370 N (ohne Zement) auf 665 N (mit Zement). Die Energieaufnahme bis zum Erreichen der F-max (E-F-max) und bei Dislokation bis 2,0 mm (E-2 mm) steigerte sich ebenfalls um 83 % und 68 %. Die Unterschiede waren signifikant. (Wilcoxon′s-Test, P<0,01) Die Ausreisskrafte F-max (ohne oder mit Zement) korrelierten eng mit der Knochendichte (r=0,9056 und r=0,9585). Unsere Resultate zeigen, da eine Augmentation mit dem α-BSMTM die prim?re Stabilit?t von Pedikelschrauben verbessern kann. Der Effekt scheint auf einer Optimierung der Kontaktfl?che und einer Aussteifung der schraubennahen Spongiosa zu beruhen. Das Material konnte geeignet sein, die Verankerung von Pedikelschrauben bei osteoporotischen Patieten zu verbessern.