WorldWideScience

Sample records for astatine 219

  1. Astatine-211: production and availability.

    Science.gov (United States)

    Zalutsky, Michael R; Pruszynski, Marek

    2011-07-01

    The 7.2-h half life radiohalogen (211)At offers many potential advantages for targeted α-particle therapy; however, its use for this purpose is constrained by its limited availability. Astatine-211 can be produced in reasonable yield from natural bismuth targets via the (209)Bi(α,2n)(211)At nuclear reaction utilizing straightforward methods. There is some debate as to the best incident α-particle energy for maximizing 211At production while minimizing production of (210)At, which is problematic because of its 138.4-day half life α-particle emitting daughter, (210)Po. The intrinsic cost for producing (211)At is reasonably modest and comparable to that of commercially available (123)I. The major impediment to (211)At availability is attributed to the need for a medium energy α-particle beam for its production. On the other hand, there are about 30 cyclotrons in the world that have the beam characteristics required for (211)At production.

  2. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    CERN Document Server

    Rothe, S; Antalic, S; Borschevsky, A; Capponi, L; Cocolios, T E; De Witte, H; Eliav, E; Fedorov, D V; Fedosseev, V N; Fink, D A; Fritzsche, S; Ghys, L; Huyse, M; Imai, N; Kaldor, U; Kudryavtsev, Yu; Köster, U; Lane, J; Lassen, J; Liberati, V; Lynch, K M; Marsh, B A; Nishio, K; Pauwels, D; Pershina, V; Popescu, L; Procter, T J; Radulov, D; Raeder, S; Rajabali, M M; Rapisarda, E; Rossel, R E; Sandhu, K; Seliverstov, M D; Sjödin, A M; Van den Bergh, P; Van Duppen, P; Venhart, M; Wakabayashi, Y; Wendt K D A

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of smallest quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the ionization threshold. The observed series of Rydberg states enabled the first determination of the ionization potential of the astatine atom, 9.317510(8) eV. New ab initio calculations were performed to support the experimental result. The measured value serves as a benchmark for quantum chemistry calculations of the properties of astatine as well as for the theoretical prediction of the ionization potential of super-heavy element 117, the heaviest homologue of astatine.

  3. 219-S chemical compatibility

    Energy Technology Data Exchange (ETDEWEB)

    GOODWIN, L.D.

    1999-08-31

    This document consists of tables of the materials that make up the ''wetted'' parts of the 219-S waste handling facility and a combination of manufacturer lists of chemicals that are not recommended.

  4. Spectroscopy of low-lying states in neutron-deficient astatine and francium nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Jakobsson, U., E-mail: ulrjak@kth.se; Cederwall, B. [KTH, The Division of Nuclear Physics, AlbaNova University Center, SE-10691 Stockholm (Sweden); Uusitalo, J.; Auranen, K.; Badran, H.; Cox, D. M.; Grahn, T.; Greenlees, P. T.; Julin, R.; Juutinen, S.; Herzáň, A.; Konki, J.; Leino, M.; Mallaburn, M.; Pakarinen, J.; Papadakis, P.; Partanen, J.; Rahkila, P.; Sandzelius, M.; Sarén, J. [University of Jyvaskyla, Department of Physics, P.O. Box 35, FI-40014 University of Jyvaskyla (Finland); and others

    2015-10-15

    Low-lying states in neutron-deficient astatine and francium nuclei have been studied by means of in-beam and delayed spectroscopy. The 13/2{sup +} state has been observed in francium nuclei with a similar down-sloping trend as in neighbouring astatine and bismuth isotopes, as a function of decreasing neutron number. A systematic trend can also now be seen for the 1/2{sup +} state both in astatine and francium nuclei, where the level energy decreases steeply as a function of neutron number when moving further away from the neutron shell closure. This trend is very similar between astatine nuclei and their francium isotones. Moreover, shape coexistence has been observed between the 13/2{sup +} state and the spherical 9/2{sup −} ground state in {sup 203}Fr and {sup 205}Fr.

  5. Comment: 219 [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Japanese medaka Oryzias latipes Oryzias_latipes_L.png 219.png Taxonomy icon (c) Database Center for Life Sci...ence licensed under CC Attribution2.1 Japan アイコン:メダカ HNI-Ⅱ系統バージョン bando 2010/02/15 15:31:07 2010/02/16 09:53:27 ...

  6. Automated astatination of biomolecules - a stepping stone towards multicenter clinical trials

    DEFF Research Database (Denmark)

    Aneheim, Emma; Albertsson, Per; Bäck, Tom

    2015-01-01

    and physical properties for use in targeted therapies for cancer. Due to the very short range of the emitted α-particles, this therapy is particularly suited to treating occult, disseminated cancers. Astatine is not intrinsically tumour-specific; therefore, it requires an appropriate tumour-specific targeting......To facilitate multicentre clinical studies on targeted alpha therapy, it is necessary to develop an automated, on-site procedure for conjugating rare, short-lived, alpha-emitting radionuclides to biomolecules. Astatine-211 is one of the few alpha-emitting nuclides with appropriate chemical...

  7. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    NARCIS (Netherlands)

    Rothe, S.; Andreyev, A. N.; Antalic, S.; Borschevsky, A.; Capponi, L.; Cocolios, T. E.; De Witte, H.; Eliav, E.; Fedorov, D. V.; Fedosseev, V. N.; Fink, D. A.; Fritzsche, S.; Ghys, L.; Huyse, M.; Imai, N.; Kaldor, U.; Kudryavtsev, Yuri; Koester, U.; Lane, J. F. W.; Lassen, J.; Liberati, V.; Lynch, K. M.; Marsh, B. A.; Nishio, K.; Pauwels, D.; Pershina, V.; Popescu, L.; Procter, T. J.; Radulov, D.; Raeder, S.; Rajabali, M. M.; Rapisarda, E.; Rossel, R. E.; Sandhu, K.; Seliverstov, M. D.; Sjoedin, A. M.; Van den Bergh, P.; Van Duppen, P.; Venhart, M.; Wakabayashi, Y.; Wendt, K. D. A.

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of the minute quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviou

  8. 12 CFR 741.219 - Investment requirements.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Investment requirements. 741.219 Section 741.219 Banks and Banking NATIONAL CREDIT UNION ADMINISTRATION REGULATIONS AFFECTING CREDIT UNIONS... Unions That Also Apply to Federally Insured State-Chartered Credit Unions § 741.219...

  9. 32 CFR 219.114 - Cooperative research.

    Science.gov (United States)

    2010-07-01

    ... cooperative research projects, each institution is responsible for safeguarding the rights and welfare of... 32 National Defense 2 2010-07-01 2010-07-01 false Cooperative research. 219.114 Section 219.114...) MISCELLANEOUS PROTECTION OF HUMAN SUBJECTS § 219.114 Cooperative research. Cooperative research projects...

  10. 33 CFR 136.219 - Authorized claimants.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Authorized claimants. 136.219 Section 136.219 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED... PROCEDURES; DESIGNATION OF SOURCE; AND ADVERTISEMENT Procedures for Particular Claims § 136.219...

  11. 36 CFR 219.1 - Purpose.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Purpose. 219.1 Section 219.1 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Purpose and Principles § 219.1 Purpose. (a) Land...

  12. 36 CFR 219.2 - Principles.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Principles. 219.2 Section 219... Forest System Land and Resource Management Planning Purpose and Principles § 219.2 Principles. The planning regulations in this subpart are based on the following principles: (a) The first priority...

  13. 22 CFR 219.160 - Communications.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Communications. 219.160 Section 219.160 Foreign... DEVELOPMENT § 219.160 Communications. (a) The agency shall take appropriate steps to ensure effective communication with applicants, participants, personnel of other Federal entities, and members of the public....

  14. 36 CFR 219.3 - Overview.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Overview. 219.3 Section 219.3 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Framework for Planning § 219.3 Overview. (a)...

  15. 49 CFR 219.17 - Construction.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Construction. 219.17 Section 219.17 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE General § 219.17 Construction. Nothing in this part— (a)...

  16. Dicty_cDB: SLC219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SL (Link to library) SLC219 (Link to dictyBase) - - - Contig-U16455-1 SLC219Z (Link... to Original site) - - SLC219Z 708 - - - - Show SLC219 Library SL (Link to library) Clone ID SLC219 (Link to...ycdb.biol.tsukuba.ac.jp/CSM/SL/SLC2-A/SLC219Q.Seq.d/ Representative seq. ID SLC21...9Z (Link to Original site) Representative DNA sequence >SLC219 (SLC219Q) /CSM/SL/SLC2-A/SLC219Q.Seq.d/ XXXXX...hqkrnk*iiflnk*hfiiilkkk Frame B: ---itrclqdrwyrycssrscrnwyh*trygrhlcpswsln*sqisrnasrttprspsr* qcrfqr*krfsqrn

  17. Dicty_cDB: SHF219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SH (Link to library) SHF219 (Link to dictyBase) - - - Contig-U16427-1 SHF219P (Link to Original site) SHF...219F 637 SHF219Z 720 SHF219P 1337 - - Show SHF219 Library SH (Link to library) Clone ID SHF...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SH/SHF2-A/SHF219Q.Seq.d/ Representative seq. ID SHF...219P (Link to Original site) Representative DNA sequence >SHF219 (SHF219Q) /CSM/SH/SHF2-A/SHF...skipntisncyvi**sfv*qtqtvllsskillsslnhfvlxs*xk*mkpllnnks nvmknvfvqlyvlslpslefqivivslnlknllkiqfvqlh*llnliqfytk

  18. 48 CFR 219.7103-1 - General.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false General. 219.7103-1 Section 219.7103-1 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program...

  19. 48 CFR 219.7103 - Procedures.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Procedures. 219.7103 Section 219.7103 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program...

  20. 36 CFR 219.30 - Plan documentation.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Plan documentation. 219.30... National Forest System Land and Resource Management Planning Planning Documentation § 219.30 Plan documentation. A plan is a repository of documents that integrates and displays the desired...

  1. 36 CFR 219.19 - Ecological, social, and economic sustainability.

    Science.gov (United States)

    2010-07-01

    ... economic sustainability. 219.19 Section 219.19 Parks, Forests, and Public Property FOREST SERVICE..., Social, and Economic Sustainability § 219.19 Ecological, social, and economic sustainability. Sustainability, composed of interdependent ecological, social, and economic elements, embodies the...

  2. 48 CFR 219.7106 - Performance reviews.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7106... mentor-protege agreements as indicated in appendix I, section I-113. The determinations made in...

  3. 48 CFR 219.7100 - Scope.

    Science.gov (United States)

    2010-10-01

    ... DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7100 Scope. This... protege firms in enhancing their capabilities and to increase participation of such firms in...

  4. 48 CFR 219.7105 - Reporting.

    Science.gov (United States)

    2010-10-01

    ... OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7105 Reporting. Mentor and protege firms must report on the progress made under mentor-protege agreements...

  5. 36 CFR 219.10 - Site-specific decisions.

    Science.gov (United States)

    2010-07-01

    ... PLANNING National Forest System Land and Resource Management Planning The Framework for Planning § 219.10... consistent with §§ 219.12 through 219.18, follow the planning framework described in §§ 219.4 through...

  6. Laser photodetachment of radioactive ions: towards the determination of the electronegativity of astatine

    CERN Multimedia

    Rothe, Sebastian; Welander, Jakob Emanuel; Chrysalidis, Katerina; Day Goodacre, Thomas; Fedosseev, Valentine; Fiotakis, Spyridon; Forstner, Oliver; Heinke, Reinhard Matthias; Johnston, Karl; Kron, Tobias; Koester, Ulli; Liu, Yuan; Marsh, Bruce; Ringvall Moberg, Annie; Rossel, Ralf Erik; Seiffert, Christoph; Studer, Dominik; Wendt, Klaus; Hanstorp, Dag

    2017-01-01

    Negatively charged ions are mainly stabilized through the electron correlation effect. A measure of the stability of a negative ion is the electron affinity, which the energy gain by attaching an electron to a neutral atom. This fundamental quantity is, due to the almost general lack of bound excited states, the only atomic property that can be determined with high accuracy for negative ions. We will present the results of the first laser photodetachment studies of radioactive negative ions at CERN-ISOLDE. The photodetachment threshold for the radiogenic iodine isotope 128I was measured successfully, demonstrating the performance of the upgraded GANDALPH experimental beam line. The first detection of photo-detached astatine atoms marks a milestone towards the determination of the EA of this radioactive element.

  7. Determination of the electron affinity of astatine and polonium by laser photodetachment

    CERN Multimedia

    We propose to conduct the first electron affinity (EA) measurements of the two elements astatine (At) and polonium (Po). Collinear photo-detachment spectroscopy will allow us to measure these quantities with an uncertainty limited only by the spectral line width of the laser. We plan to use negative ion beams of the two radioactive elements At and Po, which are only accessible on-line and at ISOLDE. The feasibility of our proposed method and the functionality of the experimental setup have been demonstrated at ISOLDE in off-line tests by the clear observation of the photo-detachment threshold for stable iodine. This proposal is based on our Letter of Intent I-148.

  8. Dicty_cDB: SFI219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available SF (Link to library) SFI219 (Link to dictyBase) - - - Contig-U13190-1 SFI219P (Link to Original site) SF...I219F 585 SFI219Z 699 SFI219P 1274 - - Show SFI219 Library SF (Link to library) Clone ID SF...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/SF/SFI2-A/SFI219Q.Seq.d/ Representative seq. ID SF...I219P (Link to Original site) Representative DNA sequence >SFI219 (SFI219Q) /CSM/SF/SFI2-A/SFI...AGTAATAATTANNAAAAAAAA sequence update 2001.11.22 Translated Amino Acid sequence cwptgnffif*FINNQNFKYFNYFVFVFNTHKMDSF

  9. Dicty_cDB: CHR219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available CH (Link to library) CHR219 (Link to dictyBase) - - - Contig-U16511-1 CHR219P (Link to Original site) CHR...219F 609 CHR219Z 786 CHR219P 1375 - - Show CHR219 Library CH (Link to library) Clone ID CHR...e URL http://dictycdb.biol.tsukuba.ac.jp/CSM/CH/CHR2-A/CHR219Q.Seq.d/ Representative seq. ID CHR...219P (Link to Original site) Representative DNA sequence >CHR219 (CHR219Q) /CSM/CH/CHR2-A/CHR...ky**firs*ywswfkw**srrc*kprfirqircf*tsigsrrn*kprfgrscf*nhf*ir trsyssn*wsts*lyc*srnscss*inr*kcl*cllkhrtnittitt

  10. 49 CFR 571.219 - Standard No. 219; Windshield zone intrusion.

    Science.gov (United States)

    2010-10-01

    ... Federal Motor Vehicle Safety Standards § 571.219 Standard No. 219; Windshield zone intrusion. S1. Scope.... S3. Application. This standard applies to passenger cars and to multipurpose passenger vehicles... removable windshields. S4. Definitions. Daylight Opening (DLO) means the maximum unobstructed...

  11. Radiological risk of actinon (/sup 219/Rn)

    Energy Technology Data Exchange (ETDEWEB)

    Crawford, D.J.

    1981-12-01

    The research reported was designed to provide information on the following subjects: (1) development of the functional relations between exposure to the /sup 219/Rn decay chain and pertinent health effects; (2) specification of the circumstances under which a significant concentration of the decay chain may occur; (3) recommendation of an exposure standard which will provide protection of the public from significant elevation of health effects; and (4) an assessment of the impact of /sup 219/Rn on determinations of the concentration of the /sup 222/Rn decay chain and/or its precursors.

  12. 48 CFR 219.7102 - General.

    Science.gov (United States)

    2010-10-01

    ... DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7102 General. The... negotiated under FAR Subpart 19.7 or under the DoD Comprehensive Subcontracting Test Program. (b) Protege...) Mentor-protege agreements that establish a developmental assistance program for a protege firm....

  13. 49 CFR 219.23 - Railroad policies.

    Science.gov (United States)

    2010-10-01

    ... .02 or greater but less than .04. (12) Information concerning the effects of alcohol misuse on an..., DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE General § 219.23 Railroad policies. (a) Whenever a breath or body fluid test is required of an employee under this part, the railroad must...

  14. 36 CFR 219.20 - Ecological sustainability.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Ecological sustainability... Sustainability § 219.20 Ecological sustainability. To achieve ecological sustainability, the responsible official... diversity and species diversity are components of ecological sustainability. The planning process...

  15. 36 CFR 219.7 - Plan decisions.

    Science.gov (United States)

    2010-07-01

    ... Forest System Land and Resource Management Planning The Framework for Planning § 219.7 Plan decisions... decisions generally do not commit resources to a site-specific action, plan decisions provide a framework... management actions necessary for the achievement of desired conditions and objectives and compliance...

  16. 36 CFR 219.9 - Revision.

    Science.gov (United States)

    2010-07-01

    ... Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Framework for Planning § 219.9 Revision. (a) Application... is a review of the overall management of a unit of the National Forest System and an opportunity...

  17. 28 CFR 2.19 - Information considered.

    Science.gov (United States)

    2010-07-01

    ..., YOUTH OFFENDERS, AND JUVENILE DELINQUENTS United States Code Prisoners and Parolees § 2.19 Information...) Recommendations regarding the prisoner's parole made at the time of sentencing by the sentencing judge and... this section. (d) Recommendations and information from sentencing judges, defense...

  18. 20 CFR 219.23 - Evidence to prove death.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence to prove death. 219.23 Section 219... EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.23 Evidence to prove death. (a) Preferred evidence of death. The best evidence of a person's death is— (1) A certified copy of or extract from...

  19. 22 CFR 219.110 - Self-evaluation.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Self-evaluation. 219.110 Section 219.110... INTERNATIONAL DEVELOPMENT § 219.110 Self-evaluation. (a) The agency shall, by April 9, 1987, evaluate its... participate in the self-evaluation process by submitting comments (both oral and written). (c) The...

  20. 48 CFR 219.505 - Rejecting Small Business Administration recommendations.

    Science.gov (United States)

    2010-10-01

    ...-Asides for Small Business 219.505 Rejecting Small Business Administration recommendations. (b) The... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Rejecting Small Business Administration recommendations. 219.505 Section 219.505 Federal Acquisition Regulations System...

  1. 49 CFR 219.301 - Testing for reasonable cause.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Testing for reasonable cause. 219.301 Section 219... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION CONTROL OF ALCOHOL AND DRUG USE Testing for Cause § 219.301 Testing for reasonable cause. (a) Authorization. A railroad may, under the conditions specified in...

  2. 36 CFR 219.21 - Social and economic sustainability.

    Science.gov (United States)

    2010-07-01

    ... sustainability. 219.21 Section 219.21 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF... Economic Sustainability § 219.21 Social and economic sustainability. To contribute to economic and social sustainability, the responsible official involves interested and affected people in planning for National...

  3. 48 CFR 219.804 - Evaluation, offering, and acceptance.

    Science.gov (United States)

    2010-10-01

    ... Business Administration (The 8(a) Program) 219.804 Evaluation, offering, and acceptance. When processing... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Evaluation, offering, and acceptance. 219.804 Section 219.804 Federal Acquisition Regulations System DEFENSE ACQUISITION...

  4. 7 CFR 58.219 - High pressure pumps and lines.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 3 2010-01-01 2010-01-01 false High pressure pumps and lines. 58.219 Section 58.219....219 High pressure pumps and lines. High pressure lines may be cleaned-in-place and shall be of such construction that dead ends, valves and the high pressure pumps can be disassembled for hand cleaning. The...

  5. 29 CFR 825.219 - Rights of a key employee.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 3 2010-07-01 2010-07-01 false Rights of a key employee. 825.219 Section 825.219 Labor....219 Rights of a key employee. (a) An employer who believes that reinstatement may be denied to a key... recover its cost of health benefit premiums. A key employee's rights under FMLA continue unless and...

  6. Ionization potentials, electron affinities, resonance excitation energies, oscillator strengths, and ionic radii of element Uus (Z = 117) and astatine.

    Science.gov (United States)

    Chang, Zhiwei; Li, Jiguang; Dong, Chenzhong

    2010-12-30

    Multiconfiguration Dirac-Fock (MCDF) method was employed to calculate the first five ionization potentials, electron affinities, resonance excitation energies, oscillator strengths, and radii for the element Uus and its homologue At. Main valence correlation effects were taken into account. The Breit interaction and QED effects were also estimated. The uncertainties of calculated IPs, EAs, and IR for Uus and At were reduced through an extrapolation procedure. The good consistency with available experimental and other theoretical values demonstrates the validity of the present results. These theoretical data therefore can be used to predict some unknown physicochemical properties of element Uus, Astatine, and their compounds.

  7. ASTATINE-211 RADIOCHEMISTRY: THE DEVELOPMENT OF METHODOLOGIES FOR HIGH ACTIVITY LEVEL RADIOSYNTHESIS

    Energy Technology Data Exchange (ETDEWEB)

    MICHAEL R. ZALUTSKY

    2012-08-08

    Targeted radionuclide therapy is emerging as a viable approach for cancer treatment because of its potential for delivering curative doses of radiation to malignant cell populations while sparing normal tissues. Alpha particles such as those emitted by 211At are particularly attractive for this purpose because of their short path length in tissue and high energy, making them highly effective in killing cancer cells. The current impact of targeted radiotherapy in the clinical domain remains limited despite the fact that in many cases, potentially useful molecular targets and labeled compounds have already been identified. Unfortunately, putting these concepts into practice has been impeded by limitations in radiochemistry methodologies. A critical problem is that the synthesis of therapeutic radiopharmaceuticals provides additional challenges in comparison to diagnostic reagents because of the need to perform radio-synthesis at high levels of radioactivity. This is particularly important for {alpha}-particle emitters such as 211At because they deposit large amounts of energy in a highly focal manner. The overall objective of this project is to develop convenient and reproducible radiochemical methodologies for the radiohalogenation of molecules with the {alpha}-particle emitter 211At at the radioactivity levels needed for clinical studies. Our goal is to address two problems in astatine radiochemistry: First, a well known characteristic of 211At chemistry is that yields for electrophilic astatination reactions decline as the time interval after radionuclide isolation from the cyclotron target increases. This is a critical problem that must be addressed if cyclotrons are to be able to efficiently supply 211At to remote users. And second, when the preparation of high levels of 211At-labeled compounds is attempted, the radiochemical yields can be considerably lower than those encountered at tracer dose. For these reasons, clinical evaluation of promising 211At

  8. 36 CFR 219.5 - Information development and interpretation.

    Science.gov (United States)

    2010-07-01

    ... PLANNING National Forest System Land and Resource Management Planning The Framework for Planning § 219.5... scale, sometimes crossing Forest Service regional administrative boundaries. Ecological information...

  9. 20 CFR 219.24 - Evidence of presumed death.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of presumed death. 219.24 Section... EVIDENCE REQUIRED FOR PAYMENT Evidence of Age and Death § 219.24 Evidence of presumed death. When a person cannot be proven dead but evidence of death is needed, the Board may presume he or she died at a...

  10. 48 CFR 1852.219-73 - Small business subcontracting plan.

    Science.gov (United States)

    2010-10-01

    ... Provisions and Clauses 1852.219-73 Small business subcontracting plan. As prescribed in 1819.708-70(a), insert the following provision: Small Business Subcontracting Plan (MAY 1999) (a) This provision is not... contain FAR clause 52.219-9, “Small Business Subcontracting Plan.” The apparent low bidder must submit...

  11. 49 CFR 219.11 - General conditions for chemical tests.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false General conditions for chemical tests. 219.11 Section 219.11 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD... for chemical tests. (a) Any employee who performs covered service for a railroad is deemed to...

  12. 49 CFR 1544.219 - Carriage of accessible weapons.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Carriage of accessible weapons. 1544.219 Section...: AIR CARRIERS AND COMMERCIAL OPERATORS Operations § 1544.219 Carriage of accessible weapons. (a... weapons, do not apply to a law enforcement officer (LEO) aboard a flight for which screening is...

  13. 42 CFR 93.219 - Preponderance of the evidence.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Preponderance of the evidence. 93.219 Section 93.219 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH...

  14. 49 CFR 1542.219 - Supplementing law enforcement personnel.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 9 2010-10-01 2010-10-01 false Supplementing law enforcement personnel. 1542.219... Operations § 1542.219 Supplementing law enforcement personnel. (a) When TSA decides, after being notified by... private law enforcement personnel are available to carry out the requirements of § 1542.215, TSA...

  15. 49 CFR 219.211 - Analysis and follow-up.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Analysis and follow-up. 219.211 Section 219.211 Transportation Other Regulations Relating to Transportation (Continued) FEDERAL RAILROAD ADMINISTRATION... Analysis and follow-up. (a) The laboratory designated in appendix B to this part undertakes prompt...

  16. 14 CFR 21.9 - Replacement and modification articles.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 1 2010-01-01 2010-01-01 false Replacement and modification articles. 21.9... CERTIFICATION PROCEDURES FOR PRODUCTS AND PARTS General § 21.9 Replacement and modification articles. (a) If a person knows, or should know, that a replacement or modification article is reasonably likely to...

  17. 18 CFR 2.19 - State and Federal comprehensive plans.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 1 2010-04-01 2010-04-01 false State and Federal comprehensive plans. 2.19 Section 2.19 Conservation of Power and Water Resources FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY GENERAL RULES GENERAL POLICY AND INTERPRETATIONS Statements of...

  18. An all-solid state laser system for the laser ion source RILIS and in-source laser spectroscopy of astatine at ISOLDE, CERN

    CERN Document Server

    Rothe, Sebastian; Nörtershäuser, W

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at ISOLDE, CERN, by the addition of an all-solid state tuneable titanium: sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE, CERN, and at ISAC, TRIUMF, radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  19. An all-solid state laser system for the laser ion sources RILIS and in-source laser spectroscopy of astatine at ISOLDE/CERN

    Energy Technology Data Exchange (ETDEWEB)

    Rothe, Sebastian

    2012-09-24

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE/CERN and at ISAC/TRIUMF radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  20. Radiobiological Effects of Alpha-Particles from Astatine-211: From DNA Damage to Cell Death

    Energy Technology Data Exchange (ETDEWEB)

    Claesson, Kristina

    2011-05-15

    In recent years, the use of high linear energy transfer (LET) radiation for radiotherapeutic applications has gained increased interest. Astatine-211 (211At) is an alpha-particle emitting radionuclide, promising for targeted radioimmunotherapy of isolated tumor cells and microscopic clusters. To improve development of safe radiotherapy using 211At it is important to increase our knowledge of the radiobiological effects in cells. During radiotherapy, both tumors and adjacent normal tissue will be irradiated and therefore, it is of importance to understand differences in the radio response between proliferating and resting cells. The aim of this thesis was to investigate effects in fibroblasts with different proliferation status after irradiation with alpha-particles from 211At or X-rays, from inflicted DNA damage, to cellular responses and biological consequences. Throughout this work, irradiation was performed with alpha-particles from 211A or X-rays. The induction and repair of double-strand breaks (DSBs) in human normal fibroblasts were investigated using pulsed-field gel electrophoresis and fragment analysis. The relative biological effectiveness (RBE) of 211At for DSB induction varied between 1.4 and 3.1. A small increase of DSBs was observed in cycling cells compared to stationary cells. The repair kinetics was slower after 211At and more residual damage was found after 24 h. Comparison between cells with different proliferation status showed that the repair was inefficient in cycling cells with more residual damage, regardless of radiation quality. Activation of cell cycle arrests was investigated using immunofluorescent labeling of the checkpoint kinase Chk2 and by measuring cell cycle distributions with flow cytometry analysis. After alpha-particle irradiation, the average number of Chk2-foci was larger and the cells had a more affected cell cycle progression for several weeks compared with X-irradiated cells, indicating a more powerful arrest after 211At

  1. 48 CFR 52.219-9 - Small business subcontracting plan.

    Science.gov (United States)

    2010-10-01

    ... Clauses 52.219-9 Small business subcontracting plan. As prescribed in 19.708(b), insert the following clause: Small Business Subcontracting Plan (OCT 2010) (a) This clause does not apply to small business... business, and women-owned small business concerns. If the offeror is submitting an individual contract...

  2. 36 CFR 219.25 - Science advisory boards.

    Science.gov (United States)

    2010-07-01

    ... social sciences. (b) Regional science advisory boards. Based upon needs identified by Regional Forester(s... including, but not limited to, the physical, biological, economic, and social sciences. Regional science...) Evaluating science consistency as described in § 219.24. (c) Work groups. With the concurrence of...

  3. 20 CFR 725.219 - Duration of entitlement; child.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 3 2010-04-01 2010-04-01 false Duration of entitlement; child. 725.219... of entitlement; child. (a) An individual is entitled to benefits as a child for each month beginning... month in which any one of the following events first occurs: (1) The child dies; (2) The child...

  4. 9 CFR 93.219 - Declaration for poultry.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Declaration for poultry. 93.219... AGRICULTURE EXPORTATION AND IMPORTATION OF ANIMALS (INCLUDING POULTRY) AND ANIMAL PRODUCTS IMPORTATION OF CERTAIN ANIMALS, BIRDS, FISH, AND POULTRY, AND CERTAIN ANIMAL, BIRD, AND POULTRY PRODUCTS;...

  5. 48 CFR 53.219 - Small Business Programs.

    Science.gov (United States)

    2010-10-01

    ... disadvantaged business (including Alaska Native Corporations and Indian tribes) and women-owned small business... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Small Business Programs... (CONTINUED) CLAUSES AND FORMS FORMS Prescription of Forms 53.219 Small Business Programs. (a) The...

  6. 29 CFR 1910.219 - Mechanical power-transmission apparatus.

    Science.gov (United States)

    2010-07-01

    ... 29 Labor 5 2010-07-01 2010-07-01 false Mechanical power-transmission apparatus. 1910.219 Section... Mechanical power-transmission apparatus. (a) General requirements. (1) This section covers all types and... apparatus located in basements. All mechanical power transmission apparatus located in basements,...

  7. 50 CFR 300.219 - Vessel monitoring system.

    Science.gov (United States)

    2010-10-01

    ... system. (a) SAC and VMS Helpdesk contact information and business hours. The contact information for the..., Hawaii Standard Time. The contact information for the NOAA Office of Law Enforcement's VMS Helpdesk for the purpose of this section is: telephone: (888) 219-9228; e-mail: ole.helpdesk@noaa.gov. The...

  8. 48 CFR 752.219-8 - Utilization of small business concerns and small disadvantaged business concerns.

    Science.gov (United States)

    2010-10-01

    ... business concerns and small disadvantaged business concerns. 752.219-8 Section 752.219-8 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 752.219-8 Utilization of small business...

  9. 76 FR 50810 - Seventh Meeting: RTCA Special Committee 219: Attitude and Heading Reference System

    Science.gov (United States)

    2011-08-16

    ... Committee 219 meeting: Attitude and Heading Reference System. SUMMARY: The FAA is issuing this notice to advise the public of a meeting of RTCA Special Committee 219: Attitude and Heading Reference System... Federal Aviation Administration Seventh Meeting: RTCA Special Committee 219: Attitude and...

  10. 75 FR 49550 - Fifth Meeting: RTCA Special Committee 219: Attitude and Heading Reference System (AHRS)

    Science.gov (United States)

    2010-08-13

    ...: Notice of RTCA Special Committee 219: Attitude and Heading Reference System (AHRS). SUMMARY: The FAA is issuing this notice to advise the public of a meeting of ] RTCA Special Committee 219: Attitude and... Federal Aviation Administration Fifth Meeting: RTCA Special Committee 219: Attitude and Heading...

  11. 48 CFR 52.219-7 - Notice of Partial Small Business Set-Aside.

    Science.gov (United States)

    2010-10-01

    ... the acquisition is for a product in a class for which the Small Business Administration has determined... Business Set-Aside. 52.219-7 Section 52.219-7 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.219-7 Notice of Partial Small Business Set-Aside. As prescribed in 19.508(d), insert...

  12. 48 CFR 52.219-6 - Notice of Total Small Business Set-Aside.

    Science.gov (United States)

    2010-10-01

    ... is for a product in a class for which the Small Business Administration has determined that there are... Business Set-Aside. 52.219-6 Section 52.219-6 Federal Acquisition Regulations System FEDERAL ACQUISITION... Clauses 52.219-6 Notice of Total Small Business Set-Aside. As prescribed in 19.508(c), insert...

  13. 36 CFR 219.22 - The overall role of science in planning.

    Science.gov (United States)

    2010-07-01

    ... in planning. 219.22 Section 219.22 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Contribution of Science § 219.22 The overall role of science in planning. (a) The responsible official must ensure that the...

  14. 36 CFR 219.12 - Collaboration and cooperatively developed landscape goals.

    Science.gov (United States)

    2010-07-01

    ... cooperatively developed landscape goals. 219.12 Section 219.12 Parks, Forests, and Public Property FOREST... Collaborative Planning for Sustainability § 219.12 Collaboration and cooperatively developed landscape goals. (a... process. (b) Cooperatively developed landscape goals. (1) The responsible official and other...

  15. 48 CFR 552.219-72 - Preparation, Submission, and Negotiation of Subcontracting Plans.

    Science.gov (United States)

    2010-10-01

    ..., and Negotiation of Subcontracting Plans. 552.219-72 Section 552.219-72 Federal Acquisition Regulations... Text of Provisions and Clauses 552.219-72 Preparation, Submission, and Negotiation of Subcontracting... Negotiation of Subcontracting Plans (JUN 2005) (a) An offeror, other than a small business concern,...

  16. 36 CFR 219.31 - Maintenance of the plan and planning records.

    Science.gov (United States)

    2010-07-01

    ... planning records. 219.31 Section 219.31 Parks, Forests, and Public Property FOREST SERVICE, DEPARTMENT OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Planning Documentation § 219.31 Maintenance of the plan and planning records. (a) Each National Forest or Grassland...

  17. Final Report for research grant "Development of Methods for High Specific Activity Labeling of Biomolecules Using Astatine-211 in Different Oxidation States"

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, D., Scott

    2011-12-14

    The overall objective of this research effort was to develop methods for labeling biomolecules with higher oxidation state species of At-211. This was to be done in an effort to develop reagents that had higher in vivo stability than the present carbon-bonded At-211-labeled compounds. We were unsuccessful in that effort, as none of the approaches studied provided reagents that were stable to in vivo deastatination. However, we gained a lot of information about At-211 in higher oxidation states. The studies proved to be very difficult as small changes in pH and other conditions appeared to change the nature of the species that obtained (by HPLC retention time analyses), with many of the species being unidentifiable. The fact that there are no stable isotopes of astatine, and the chemistry of the nearest halogen iodine is quite different, made it very difficult to interpret results of some experiments. With that said, we believe that a lot of valuable information was obtained from the studies. The research effort evaluated: (1) methods for chemical oxidation of At-211, (2) approaches to chelation of oxidized At-211, and (3) approaches to oxidation of astatophenyl compounds. A major hurdle that had to be surmounted to conduct the research was the development of HPLC conditions to separate and identify the various oxidized species formed. Attempts to develop conditions for separation of iodine and astatine species by normal and reversed-phase TLC and ITLC were not successful. However, we were successful in developing conditions (from a large number of attempts) to separate oxidized forms of iodine ([I-125]iodide, [I-125]iodate and [I-125]periodate) and astatine ([At-211]astatide, [At-211]astatate, [At-211]perastatate, and several unidentified At-211 species). Information on the basic oxidation and characterization of At-211 species is provided under Objective 1. Conditions were developed to obtain new At-211 labeling method where At-211 is chelated with the DOTA and

  18. Birth Defects Among Children Born to Human Immunodeficiency Virus-Infected Women Pediatric AIDS Clinical Trials Protocols 219 and 219C

    NARCIS (Netherlands)

    Brogly, Susan B.; Abzug, Mark J.; Watts, D. Heather; Cunningham, Coleen K.; Williams, Paige L.; Oleske, James; Conway, Daniel; Sperling, Rhoda S.; Spiegel, Hans; Van Dyke, Russell B.

    2010-01-01

    Background: Some studies have detected associations between in utero antiretroviral therapy (ARV) exposure and birth defects but evidence is inconclusive. Methods: A total of 2202 human immunodeficiency virus (HIV)-exposed children enrolled in the Pediatric AIDS Clinical Trials Group 219 and 219 C p

  19. Mass determination of K2-19b and K2-19c from radial velocities and transit timing variations

    CERN Document Server

    Nespral, D; Deeg, H J; Borsato, L; Fridlund, M C V; Barragan, O; Grziwa, S; Korth, J; Cabrera, J; Csizmadia, Sz; Nowak, G; Kuutma, T; Saario, J; Eigmuller, P; Erikson, A; Guenther, E W; Hatzes, A P; Rodriguez, P Montanes; Palle, E; Patzold, M; Prieto-Arranz, J; Rauer, H; Sebastian, D

    2016-01-01

    We present FIES@NOT and HARPS-N@TNG radial velocity follow-up observations of K2-19, a compact planetary system hosting three planets, of which the two larger ones, namely K2-19b and K2-19c, are close to the 3:2 mean motion resonance. The masses of these larger planets have previously been derived from transit timing only. An analysis considering only the radial velocity measurements is able to detect only K2-19b, the largest and more massive planet in the system, with a mass of $71.7\\pm6.3$ M${_\\oplus}$. We also used the TRADES code to simultaneously model both our RV measurements and the existing transit-timing measurements. We derived a mass of K2-19b of $59.5^{+7.2}_{-11.4}$ M${_\\oplus}$ and of K2-19c of $9.7^{+3.9}_{-2.0}$ M${_\\oplus}$. A prior K2-19b mass estimated by Barros 2015, based exclusively on transit timing measurements, is only consistent with our combined TTV and RV analysis, but not with our analysis based purely on RV measurements. K2-19b supports the suspicion that planet masses and densit...

  20. Anesthetic and surgical complications in 219 cases of myotonic dystrophy.

    Science.gov (United States)

    Mathieu, J; Allard, P; Gobeil, G; Girard, M; De Braekeleer, M; Bégin, P

    1997-12-01

    The objective of this study was to assess the frequency, type, and severity of perioperative complications after a first surgery under general anesthesia in patients with myotonic dystrophy (DM) and to measure the association with suspected risk factors. Numerous cases of perioperative complications in DM patients have been reported. Hazards have been associated with the use of thiopentone, suxamethonium, neostigmine, and halothane. A retrospective study of perioperative complications was conducted for 219 DM patients who had their first surgery under general anesthesia at the Chicoutimi Hospital. The overall frequency of complications was 8.2% (18 of 219). Most complications (16 of 18) were pulmonary, including five patients with acute ventilatory failure necessitating ventilatory support, four patients with atelectasis, and three patients with pneumonia. Using multivariate analysis, we found that the risk of perioperative pulmonary complications (PPC) was significantly higher after an upper abdominal surgery (odds ratio (OR), 24.4; 95% CI, 4.0 to 149.3) and for patients with a severe muscular disability, as assessed by the presence of proximal limb weakness (OR, 14.1; 95% CI, 1.5 to 134.4). The likelihood of PPC was not related to any specific anesthetic drug. Because of the increased risk of PPC, careful monitoring during the early postoperative period, protection of upper airways, chest physiotherapy, and incentive spirometry are mandatory in all symptomatic DM patients, particularly those with a severe muscular disability or those who have undergone an upper abdominal surgery.

  1. 20 CFR 219.33 - Evidence of a deemed valid marriage.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of a deemed valid marriage. 219.33... EVIDENCE REQUIRED FOR PAYMENT Evidence of Relationship § 219.33 Evidence of a deemed valid marriage. (a) Preferred evidence. Preferred evidence of a deemed valid marriage is— (1) Evidence of a ceremonial...

  2. 20 CFR 219.30 - When evidence of marriage is required.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When evidence of marriage is required. 219.30... EVIDENCE REQUIRED FOR PAYMENT Evidence of Relationship § 219.30 When evidence of marriage is required. (a) When an application is filed for benefits. Documentary evidence of marriage is required when...

  3. 20 CFR 219.35 - Evidence that a marriage has ended.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence that a marriage has ended. 219.35... EVIDENCE REQUIRED FOR PAYMENT Evidence of Relationship § 219.35 Evidence that a marriage has ended. (a) Preferred evidence. Preferred evidence that a marriage has ended is— (1) A certified copy of the decree...

  4. 20 CFR 219.32 - Evidence of a common-law marriage.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of a common-law marriage. 219.32... EVIDENCE REQUIRED FOR PAYMENT Evidence of Relationship § 219.32 Evidence of a common-law marriage. (a) Preferred evidence. Evidence of a common-law marriage must give the reasons why the informant believes...

  5. 76 FR 80447 - Eighth Meeting: RTCA Special Committee 219: Attitude and Heading Reference Systems (AHRS)

    Science.gov (United States)

    2011-12-23

    ... Federal Aviation Administration Eighth Meeting: RTCA Special Committee 219: Attitude and Heading Reference...). ACTION: Notice of RTCA Special Committee 219: Attitude and Heading Reference Systems (AHRS). SUMMARY: The FAA is issuing this notice to advise the public of the eighth meeting of RTCA Special Committee...

  6. 48 CFR 52.219-4 - Notice of price evaluation preference for HUBZone small business concerns.

    Science.gov (United States)

    2010-10-01

    ... successful offers from small business concerns. (2) The factor of 10 percent shall be applied on a line item... preference for HUBZone small business concerns. 52.219-4 Section 52.219-4 Federal Acquisition Regulations... business concerns. As prescribed in 19.1308(b), insert the following clause: Notice of Price...

  7. 48 CFR 52.219-23 - Notice of Price Evaluation Adjustment for Small Disadvantaged Business Concerns.

    Science.gov (United States)

    2010-10-01

    ... disadvantaged business concern in accordance with 13 CFR 124, subpart B, and a decision on that application is... disadvantaged business concerns that have not waived the adjustment; and (ii) An otherwise successful offer from... Adjustment for Small Disadvantaged Business Concerns. 52.219-23 Section 52.219-23 Federal...

  8. 48 CFR 2452.219-70 - Small business subcontracting plan compliance.

    Science.gov (United States)

    2010-10-01

    ... of Provisions and Clauses 2452.219-70 Small business subcontracting plan compliance. As prescribed in 2419.708(d), insert the following provision: Small Business Subcontracting Plan Compliance (FEB 2006... the clause at FAR 52.219-9, Small Business Subcontracting Plan. (c) The government will...

  9. 49 CFR 219.102 - Prohibition on abuse of controlled substances.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Prohibition on abuse of controlled substances. 219....102 Prohibition on abuse of controlled substances. No employee who performs covered service may use a controlled substance at any time, whether on duty or off duty, except as permitted by § 219.103....

  10. 32 CFR 219.123 - Early termination of research support: Evaluation of applications and proposals.

    Science.gov (United States)

    2010-07-01

    ....123 Early termination of research support: Evaluation of applications and proposals. (a) The... 32 National Defense 2 2010-07-01 2010-07-01 false Early termination of research support: Evaluation of applications and proposals. 219.123 Section 219.123 National Defense Department of...

  11. 48 CFR 652.219-70 - Department of State Subcontracting Goals.

    Science.gov (United States)

    2010-10-01

    ... Subcontracting Goals. 652.219-70 Section 652.219-70 Federal Acquisition Regulations System DEPARTMENT OF STATE... Department of State Subcontracting Goals. As prescribed in 619.708-70, insert a provision substantially the same as follows: Department of State Subcontracting Goals (APR 2004) (a) The offeror shall provide...

  12. 25 CFR 166.219 - How do I acquire a permit through negotiation?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false How do I acquire a permit through negotiation? 166.219... PERMITS Permit Requirements Obtaining A Permit § 166.219 How do I acquire a permit through negotiation? (a...) Upon the conclusion of negotiations with the Indian landowners or their representatives, and...

  13. 32 CFR 219.118 - Applications and proposals lacking definite plans for involvement of human subjects.

    Science.gov (United States)

    2010-07-01

    ... plans for involvement of human subjects. 219.118 Section 219.118 National Defense Department of Defense....118 Applications and proposals lacking definite plans for involvement of human subjects. Certain types... agencies with the knowledge that subjects may be involved within the period of support, but definite...

  14. 20 CFR 219.53 - Evidence of having a child in care.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of having a child in care. 219.53... EVIDENCE REQUIRED FOR PAYMENT Other Evidence Requirements § 219.53 Evidence of having a child in care. (a) Preferred evidence of having a child in care. Preferred evidence of having a child in care is— (1) If...

  15. 49 CFR 238.219 - Truck-to-car-body attachment.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Truck-to-car-body attachment. 238.219 Section 238... I Passenger Equipment § 238.219 Truck-to-car-body attachment. Passenger equipment shall have a truck-to-car-body attachment with an ultimate strength sufficient to resist without failure the...

  16. Extraction and purification of {sup 227}Ac and development of solid {sup 219}Rn source

    Energy Technology Data Exchange (ETDEWEB)

    Tang, Quan; Qiu, Shoukang; Xiao, Detao; Zhou, Yaohui; An, Xiaogang [University of South China, Hengyang (China). Radon Key Laboratory of Hunan Province/School of Nuclear Science and Technology

    2014-04-01

    The method of {sup 227}Ac extraction and purification from high-grade uranium ore and the test results of solid {sup 219}Rn source made from {sup 227}Ac are reported in this paper. With five years of follow-up monitoring, radiochemical purity of {sup 227}Ac and the emanation power of solid {sup 219}Rn source has been checked by emanation method and γ-spectrometry, the results showed that {sup 228}Th, {sup 231}Pa and {sup 226}Ra have been effectively removed and the emanation power of {sup 219}Rn source is about 80%. The long-term test results also showed that the {sup 219}Rn emanation rate remains stable in a wide air humidity range (40% ∝ 90%). Though the {sup 219}Rn source has not been accurately calibrated yet, it has been applied in the research for delay coincidence measurement of {sup 223}Ra. (orig.)

  17. 32 CFR 219.120 - Evaluation and disposition of applications and proposals for research to be conducted or...

    Science.gov (United States)

    2010-07-01

    ... proposals for research to be conducted or supported by a Federal Department or Agency. 219.120 Section 219...) MISCELLANEOUS PROTECTION OF HUMAN SUBJECTS § 219.120 Evaluation and disposition of applications and proposals for research to be conducted or supported by a Federal Department or Agency. (a) The department...

  18. 47 CFR 95.219 - (R/C Rule 19) How do I answer correspondence from the FCC?

    Science.gov (United States)

    2010-10-01

    ... from the FCC? 95.219 Section 95.219 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED... You Need to Know § 95.219 (R/C Rule 19) How do I answer correspondence from the FCC? (a) If it appears to the FCC that you have violated the Communications Act or FCC rules, the FCC may send you...

  19. Dysregulation of microRNA-219 promotes neurodegeneration through post-transcriptional regulation of tau

    Science.gov (United States)

    Santa-Maria, Ismael; Alaniz, Maria E.; Renwick, Neil; Cela, Carolina; Fulga, Tudor A.; Van Vactor, David; Tuschl, Thomas; Clark, Lorraine N.; Shelanski, Michael L.; McCabe, Brian D.; Crary, John F.

    2015-01-01

    Tau is a highly abundant and multifunctional brain protein that accumulates in neurofibrillary tangles (NFTs), most commonly in Alzheimer’s disease (AD) and primary age-related tauopathy. Recently, microRNAs (miRNAs) have been linked to neurodegeneration; however, it is not clear whether miRNA dysregulation contributes to tau neurotoxicity. Here, we determined that the highly conserved brain miRNA miR-219 is downregulated in brain tissue taken at autopsy from patients with AD and from those with severe primary age-related tauopathy. In a Drosophila model that produces human tau, reduction of miR-219 exacerbated tau toxicity, while overexpression of miR-219 partially abrogated toxic effects. Moreover, we observed a bidirectional modulation of tau levels in the Drosophila model that was dependent on miR-219 expression or neutralization, demonstrating that miR-219 regulates tau in vivo. In mammalian cellular models, we found that miR-219 binds directly to the 3′-UTR of the tau mRNA and represses tau synthesis at the post-transcriptional level. Together, our data indicate that silencing of tau by miR-219 is an ancient regulatory mechanism that may become perturbed during neurofibrillary degeneration and suggest that this regulatory pathway may be useful for developing therapeutics for tauopathies. PMID:25574843

  20. 18 CFR 367.2190 - Account 219, Accumulated other comprehensive income.

    Science.gov (United States)

    2010-04-01

    ... POWER ACT AND NATURAL GAS ACT Balance Sheet Chart of Accounts Proprietary Capital § 367.2190 Account 219... FEDERAL ENERGY REGULATORY COMMISSION, DEPARTMENT OF ENERGY REGULATIONS UNDER THE PUBLIC UTILITY...

  1. An automated flow system incorporating in-line acid dissolution of bismuth metal from a cyclotron irradiated target assembly for use in the isolation of astatine-211

    Energy Technology Data Exchange (ETDEWEB)

    O’Hara, Matthew J.; Krzysko, Anthony J.; Niver, Cynthia M.; Morrison, Samuel S.; Owsley, Stanley L.; Hamlin, Donald K.; Dorman, Eric F.; Scott Wilbur, D.

    2017-04-01

    Astatine-211 (211At) is a promising cyclotron-produced radionuclide being investigated for use in targeted alpha therapy of blood borne and metastatic cancers, as well as treatment of tumor remnants after surgical resections. The isolation of trace quantities of 211At, produced within several grams of a Bi metal cyclotron target, involves a complex, multi-step procedure: (1) Bi metal dissolution in strong HNO3, (2) distillation of the HNO3 to yield Bi salts containing 211At, (3) dissolution of the salts in strong HCl, (4) solvent extraction of 211At from bismuth salts with diisopropyl ether (DIPE), and (5) back-extraction of 211At from DIPE into NaOH, leading to a purified 211At product. Step (1) has been addressed first to begin the process of automating the onerous 211At isolation process. A computer-controlled Bi target dissolution system has been designed. The system performs in-line dissolution of Bi metal from the target assembly using an enclosed target dissolution block, routing the resulting solubilized 211At/Bi mixture to the subsequent process step. The primary parameters involved in Bi metal solubilization (HNO3 concentration and influent flow rate) were optimized prior to evaluation of the system performance on replicate cyclotron irradiated targets. The results indicate that the system performs reproducibly, having nearly quantitative release of 211At from irradiated targets, with cumulative 211At recoveries that follow a sigmoidal function. The predictable nature of the 211At release profile allows the user to tune the system to meet target processing requirements.

  2. MicroRNA-219 modulates NMDA receptor-mediated neurobehavioral dysfunction

    DEFF Research Database (Denmark)

    Kocerha, Jannet; Faghihi, Mohammad Ali; Lopez-Toledano, Miguel A;

    2009-01-01

    N-methyl-D-aspartate (NMDA) glutamate receptors are regulators of fast neurotransmission and synaptic plasticity in the brain. Disruption of NMDA-mediated glutamate signaling has been linked to behavioral deficits displayed in psychiatric disorders such as schizophrenia. Recently, noncoding RNA...... significantly modulated behavioral responses associated with disrupted NMDA receptor transmission. Furthermore, pretreatment with the antipsychotic drugs haloperidol and clozapine prevented dizocilpine-induced effects on miR-219. Taken together, these data support an integral role for miR-219 in the expression...... molecules such as microRNAs (miRNAs) have emerged as critical regulators of neuronal functions. Here we show that pharmacological (dizocilpine) or genetic (NR1 hypomorphism) disruption of NMDA receptor signaling reduces levels of a brain-specific miRNA, miR-219, in the prefrontal cortex (PFC) of mice...

  3. 38 CFR 21.219 - Supplies consisting of clothing, magazines and periodicals, and items which may be personally...

    Science.gov (United States)

    2010-07-01

    ... clothing, magazines and periodicals, and items which may be personally used by the veteran. 21.219 Section....219 Supplies consisting of clothing, magazines and periodicals, and items which may be personally used... will be supplied. (b) Furnishing magazines and periodicals. Appropriate past issues of...

  4. 48 CFR 52.219-19 - Small Business Concern Representation for the Small Business Competitiveness Demonstration Program.

    Science.gov (United States)

    2010-10-01

    ... Representation for the Small Business Competitiveness Demonstration Program. 52.219-19 Section 52.219-19 Federal... Representation for the Small Business Competitiveness Demonstration Program. As prescribed in 19.1008(a), insert the following provision: Small Business Concern Representation for the Small Business...

  5. 20 CFR 219.31 - Evidence of a valid ceremonial marriage.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Evidence of a valid ceremonial marriage. 219... marriage. (a) Preferred evidence. Preferred evidence of a ceremonial marriage is— (1) A copy of the public record of the marriage, certified by the custodian of the record or by a Board employee; (2) A copy of...

  6. 48 CFR 252.219-7004 - Small business subcontracting plan (test program).

    Science.gov (United States)

    2010-10-01

    ... AND CONTRACT CLAUSES Text of Provisions And Clauses 252.219-7004 Small business subcontracting plan... contract or subcontract. (b) The Offeror's comprehensive small business subcontracting plan and its... “Utilization of Small Business Concerns,” or (2) an approved plan required by this clause, shall be a...

  7. 48 CFR 852.219-9 - VA Small business subcontracting plan minimum requirements.

    Science.gov (United States)

    2010-10-01

    ... Provisions and Clauses 852.219-9 VA Small business subcontracting plan minimum requirements. As prescribed in subpart 819.709, insert the following clause: VA Small Business Subcontracting Plan Minimum Requirements... plan, the minimum goals for award of subcontracts to service-disabled veteran-owned small...

  8. 48 CFR 219.7104 - Developmental assistance costs eligible for reimbursement or credit.

    Science.gov (United States)

    2010-10-01

    ... BUSINESS PROGRAMS Pilot Mentor-Protege Program 219.7104 Developmental assistance costs eligible for reimbursement or credit. (a) Developmental assistance provided under an approved mentor-protege agreement is... debarred while performing under an approved mentor-protege agreement, the mentor firm may not be...

  9. 49 CFR Appendix C to Part 219 - Post-Accident Testing Specimen Collection

    Science.gov (United States)

    2010-10-01

    ... for forensic toxicology. B. Specimens requested, in order of preference: a. Blood—20 milliliters or...-Accident Testing Blood/Urine Custody and Control Form (49 CFR part 219) (Form FRA F 6180.74 (revised.... Collection of blood and urine specimens is required to be conducted at an independent medical...

  10. 27 CFR 28.219 - Return of wine withdrawn for export with benefit of drawback.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Return of wine withdrawn... Exportation of Wine With Benefit of Drawback § 28.219 Return of wine withdrawn for export with benefit of drawback. When notice is filed by an exporter as provided in § 28.220, wine on which the tax has been...

  11. 36 CFR 219.14 - Involvement of State and local governments.

    Science.gov (United States)

    2010-07-01

    ... OF AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Collaborative Planning for Sustainability § 219.14 Involvement of State and local governments. The responsible official... the planning process, including the identification of issues; and (b) Contribute to the...

  12. 36 CFR 223.219 - Sustainable harvest of special forest products.

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 2 2010-07-01 2010-07-01 false Sustainable harvest of....219 Sustainable harvest of special forest products. (a) Sustainable harvest levels. Prior to offering... product's sustainable harvest level. A special forest product's sustainable harvest level is the...

  13. 41 CFR 302-3.219 - Is there a limit on how many times I may receive reimbursement for tour renewal travel?

    Science.gov (United States)

    2010-07-01

    ... many times I may receive reimbursement for tour renewal travel? 302-3.219 Section 302-3.219 Public Contracts and Property Management Federal Travel Regulation System RELOCATION ALLOWANCES RELOCATION....219 Is there a limit on how many times I may receive reimbursement for tour renewal travel? (a) If...

  14. Conceptual design report, 219-S secondary containment upgrade, Project W-178

    Energy Technology Data Exchange (ETDEWEB)

    Beyer, J.J. [Kaiser Engineers Hanford Co., Richland, WA (United States)

    1993-05-01

    The 219-S Facility is located in the 200-West Area on the Hanford Site and was constructed in 1951. The facility receives and treats liquid, low-level mixed waste from the 222-S Laboratory prior to transfer of that waste to the SY Tank Farm. The 219-S Facility consists of Cell A containing Tanks 101 and 102 and Cell B containing Tank 103 and a spare space. Project W-178 will modify the 219-S Facility to bring it into compliance with the tank system standards in WAC 173-303-640. The secondary containment upgrade will consist of a stainless steel cell liner in both Cell A and the spare space in Cell B. Additionally, Cell B will be modified by taking Tank 103 out of service and installing a new tank: Tank 104. The construction work will be accomplished in phases to minimize service interruption to the 222-S Laboratory. The proposed design and construction method is the most cost effective of four alternatives evaluated during a value engineering session. Project W-178 is a fiscal year 1995 Line Item. Total estimated construction costs of the project are $2,600,000; other project costs are $710,000. The total project cost is $3,300,000.

  15. Structural basis of jasmonate-amido synthetase FIN219 in complex with glutathione S-transferase FIP1 during the JA signal regulation

    Science.gov (United States)

    Chen, Chun-Yen; Ho, Sih-Syun; Kuo, Tzu-Yen; Cheng, Yi-Sheng

    2017-01-01

    Far-red (FR) light-coupled jasmonate (JA) signaling is necessary for plant defense and development. FR insensitive 219 (FIN219) is a member of the Gretchen Hagen 3 (GH3) family of proteins in Arabidopsis and belongs to the adenylate-forming family of enzymes. It directly controls biosynthesis of jasmonoyl-isoleucine in JA-mediated defense responses and interacts with FIN219-interacting protein 1 (FIP1) under FR light conditions. FIN219 and FIP1 are involved in FR light signaling and are regulators of the interplay between light and JA signaling. However, how their interactions affect plant physiological functions remains unclear. Here, we demonstrate the crystal structures of FIN219–FIP1 while binding with substrates at atomic resolution. Our results show an unexpected FIN219 conformation and demonstrate various differences between this protein and other members of the GH3 family. We show that the rotated C-terminal domain of FIN219 alters ATP binding and the core structure of the active site. We further demonstrate that this unique FIN219–FIP1 structure is crucial for increasing FIN219 activity and determines the priority of substrate binding. We suggest that the increased FIN219 activity resulting from the complex form, a conformation for domain switching, allows FIN219 to switch to its high-affinity mode and thereby enhances JA signaling under continuous FR light conditions. PMID:28223489

  16. Field Trial of 40 Gbit/s ETDM Prototype System over 219 km of Installed Single Mode Fiber

    Institute of Scientific and Technical Information of China (English)

    Sang Soo Lee; Hyun Woo Cho; Sang Kyu Lim; Ki Ho Han; Jin Soo Han; Moo Jung Chu; Je Soo Ko; Kyeong-Mo Yoon; Yong-Gi Lee

    2003-01-01

    Transmission of 40Gbit/s NRZ signal was successfully demonstrated over 219km of installed SMF in KT's Daejeon area network. After transmission, the measured power penalty was 0.5dB for all the tributary channels.

  17. The TLX-miR-219 cascade regulates neural stem cell proliferation in neurodevelopment and schizophrenia iPSC model.

    Science.gov (United States)

    Murai, Kiyohito; Sun, Guoqiang; Ye, Peng; Tian, E; Yang, Su; Cui, Qi; Sun, Guihua; Trinh, Daniel; Sun, Olivia; Hong, Teresa; Wen, Zhexing; Kalkum, Markus; Riggs, Arthur D; Song, Hongjun; Ming, Guo-li; Shi, Yanhong

    2016-03-11

    Dysregulated expression of miR-219, a brain-specific microRNA, has been observed in neurodevelopmental disorders, such as schizophrenia (SCZ). However, its role in normal mammalian neural stem cells (NSCs) and in SCZ pathogenesis remains unknown. We show here that the nuclear receptor TLX, an essential regulator of NSC proliferation and self-renewal, inhibits miR-219 processing. miR-219 suppresses mouse NSC proliferation downstream of TLX. Moreover, we demonstrate upregulation of miR-219 and downregulation of TLX expression in NSCs derived from SCZ patient iPSCs and DISC1-mutant isogenic iPSCs. SCZ NSCs exhibit reduced cell proliferation. Overexpression of TLX or inhibition of miR-219 action rescues the proliferative defect in SCZ NSCs. Therefore, this study uncovers an important role for TLX and miR-219 in both normal neurodevelopment and in SCZ patient iPSC-derived NSCs. Moreover, this study reveals an unexpected role for TLX in regulating microRNA processing, independent of its well-characterized role in transcriptional regulation.

  18. Inverse Compton X-rays from the radio galaxy 3C 219

    CERN Document Server

    Comastri, A; Dallacasa, D; Bondi, M; Pedani, M; Setti, G

    2003-01-01

    We report the results from a Chandra observation of the powerful nearby (z=0.1744) radio galaxy 3C 219. We find evidence for non-thermal X-ray emission from the radio lobes which fits fairly well with a combination of inverse Compton scattering of Cosmic Microwave Background radiation and of nuclear photons with the relativistic electrons in the lobes. The comparison between radio synchrotron and IC emission yields a magnetic field strength significantly lower (about a factor 3) than that calculated under minimum energy conditions; the source energetics is then dominated by the relativistic particles.

  19. VizieR Online Data Catalog: K2-19b light curve (Armstrong+, 2015)

    Science.gov (United States)

    Armstrong, D. J.; Santerne, A.; Veras, D.; Barros, S. C. C.; Demangeon, O.; Lillo-Box, J.; McCormac, J.; Osborn, H. P.; Tsantaki, M.; Almenara, J.-M.; Barrado, D.; Boisse, I.; Bonomo, A. S.; Brown, D. J. A.; Bruno, G.; Rey Cerda, J.; Courcol, B.; Deleuil, M.; Diaz, R. F.; Doyle, A. P.; Hebrard, G.; Kirk, J.; Lam, K. W. F.; Pollacco, D. L.; Rajpurohit, A.; Spake, J.; Walker, S. R.

    2015-08-01

    The Near Infrared Transiting ExoplanetS (NITES) Telescope is a semi-robotic 0.4m (f/10) Meade LX200GPS Schmidt-Cassegrain telescope installed at the ORM, La Palma. One transit of K2-19b was observed on 2015 Feb 28. The telescope was defocused slightly to 3.3 FWHM and 814 images of 20s exposure time were obtained with 5s dead time between each. Observations were obtained without a filter. The table presents data taken with the NITES telescope shown in Figure 1 of the publication. (1 data file).

  20. 温室专用番茄新品种‘冀东219'%A New Tomato Cultivar for Greenhouse Jidong 219

    Institute of Scientific and Technical Information of China (English)

    孙中峰; 曹霞; 武春成; 毛秀杰; 代波; 王学东

    2012-01-01

    Jidong 219 is a F1 by several generations of screening and crossing with import tomato. It has unlimited branches and sparse leaves and it grows vigorously. The first inflorescence is situated between the sixth and ninth node, inflorescence interval of 2 to 3, and each inflorescence bears 8 - 15 tomatos. The average fruit mass is 38 - 42 g. The fruit is red, round. Fruit shape index is 0.89. Vitamin C content is 0.17 mg.g-1. The soluble solids content is 6.18%. Organic acid content is 0.79%. Ratio of sugar to acid is 7.82. Fruit is sweet and sour, flesh is thick. It is tolerant to storage and transportation. It is high-resistant to TYLCV, TMV, southern bacterial wilt and leaf mold, and mid-resistant to gray mold. It is suitable for protected cultivation.%番茄杂种一代新品种‘冀东219’,植株为无限生长类型,叶片较稀疏,生长势较强,第6-9节着生第一花序,花序间隔2-3节,每穗结果8-15个。单果质量38-42g,果实红色,圆形,果面光滑,果形指数0.89,果实中维生素C含量为0.17mg·g-1,可溶性固型物含量为6.18%,有机酸含量为0.79%,糖酸比为7.82,酸甜适口,果肉较厚,耐贮运。高抗TYLCV、TMV、青枯病、叶霉病,中抗灰霉病。适合保护地栽培。

  1. Photo-dynamical mass determination of the multi-planetary system K2-19

    CERN Document Server

    Barros, S C C; Demangeon, O; Tsantaki, M; Santerne, A; Armstrong, D J; Barrado, D; Brown, D; Deleuil, M; Lillo-Box, J; Osborn, H; Pollacco, D; Abe, L; Andre, P; Bendjoya, P; Boisse, I; Bonomo, A S; Bouchy, F; Bruno, G; Cerda, J Rey; Courcol, B; Díaz, R F; Hébrard, G; Kirk, J; Lachurié, J C; Lam, K W F; Martinez, P; McCormac, J; Moutou, C; Rajpurohit, A; Rivet, J -P; Spake, J; Suarez, O; Toublanc, D; Walker, S R

    2015-01-01

    K2-19 is the second multi-planetary system discovered with K2 observations. The system is composed of two Neptune size planets close to the 3:2 mean-motion resonance. To better characterise the system we obtained two additional transit observations of K2-19b and five additional radial velocity observations. These were combined with K2 data and fitted simultaneously with the system dynamics (photo-dynamical model) which increases the precision of the transit time measurements. The higher transit time precision allows us to detect the chopping signal of the dynamic interaction of the planets that in turn permits to uniquely characterise the system. Although the reflex motion of the star was not detected, dynamic modelling of the system allowed us to derive planetary masses of $M_b= 44 \\pm 12\\, M_{\\oplus}$ and $M_c = 15.9 \\pm 7.0\\, M_{\\oplus}$ for the inner and the outer planets respectively, leading to densities close to Uranus. We also show that our method allows the derivation of mass ratios using only the 80...

  2. Effect of miR-219-5p on malignant phenotype of glioblastoma cells%MiR-219-5p对人脑成胶质细胞瘤恶性表型的影响

    Institute of Scientific and Technical Information of China (English)

    刘彦伟; 颜伟; 王永志; 张伟; 游赣; 唐铠

    2012-01-01

    目的:探讨miR-219-5p对人脑成胶质细胞瘤(glioblastoma,GBM)的恶性表型——增殖、凋亡和侵袭的影响,初步寻找与miR-219-5p发挥抑癌作用有关的靶点基因.方法:在60例GBM组织中分析miR-219-5p表达水平及mRNA表达谱,筛选与miR-219-5p表达量呈负相关的mRNA;选取前50个相关性最大的mRNA,用基因功能分析软件DAVID从中筛选出与GBM恶性进展相关的2组mRNA;最后用4个在线靶点预测网站从这2组中预测miR-219-5p的潜在靶点.采用MTT法、流式细胞术和Transwell实验初步验证miR-219-5p对GBM细胞增殖、凋亡和侵袭的影响.结果:60例GBM组织中筛出14个与增殖和凋亡相关的基因和5个与侵袭相关的基因(P<0.001);在这19个候选基因中预测到4个基因(TWIST1、MYO1B、WEE1和SPRED2)是miR-219-5p的潜在靶点.实验初步证明,miR-219-5p能够抑制GBM细胞的增殖和侵袭以及促进细胞凋亡(P<0.05).结论:MiR-219-5p可能通过作用于多个靶点对GBM的恶性表型起到抑制作用.%Objective: To investigate the effect of rniR-219-5p on malignant phenotype of glioblastoma cells involving proliferation, apoptosis and invasion, and to preliminarily determine the candidate target genes of miR-219-5p related to the inhibition of cancer. Methods: The inverse relationship between mRNAs and miR-219-5p in glioblastoma tissues from sixty cases was obtained by analysis of miR-219-5p expression level and mRNA expression profiling. DAVID software for functional analysis was employed to analyze the functions of the top 50 mRNAs and screen out two sets of mRNAs related to glioblastoma progression. The target genes of miR-219-5p were screened out from the two sets of miRNAs on four websites of online target-binding prediction. MTT assay, flow cytometry (FCM) assay and Transwell assay were performed to detect the effects of miR-219-5p on the proliferation, apoptosis and invasion of human glioblastoma cells, respectively. Results: Fourteen

  3. 固体219Rn 源的γ能谱法放射性纯度检验%Determination of Radioactivity Purity of Solid 219 Rn Source by γ-ray Spectrometry

    Institute of Scientific and Technical Information of China (English)

    唐泉; 安小刚; 丘寿康

    2014-01-01

    对利用从铀矿石中提取得到的227 Ac制备的固体219 Rn源进行了γ能谱分析,确定了227 Ac的4个子体核素227 T h、223 Ra、219 Rn和211 Bi的活度,并分析了能对219 Rn造成干扰的222 Rn、220 Rn母体核素226 Ra、224 Ra的活度。待227 Ac及其子体达到放射性平衡后,通过测量227 Th的235.97、256.25 keV ,223 Ra的154.21 keV ,219 Rn的401.81 keV ,211 Bi的351.059 keV共5条γ射线,最终确定固体219 Rn源中227 T h、223 Ra、219 Rn和211 Bi的活度为(1069±3)、(1079±5)、(1095±13)、(1096±14)和(11089±4) Bq ,固体219 Rn源的平均活度为(1093±8) Bq;通过测量224 Ra子体212 Pb的238.632 keV、208 T l的583.191 keVγ射线以及226 Ra子体214 Bi的609.312、1120.287 keV γ射线得到226 Ra与224 Ra的平均活度分别为5.12 Bq及0.433 Bq ,远低于固体219 Rn源的平均活度,说明固体219 Rn源放射性纯度较高。以上结果表明,此源有望制成标准固体219 Rn源以用于延迟符合法测223 Ra、227 Ac装置的刻度。%Radioactivity purity of the solid 219 Rn source made using 227 Ac extracted from uranium ore were determined by γ‐spectrometry .The activities of 227 Th ,223 Ra ,219 Rn and 211 Bi produced by the decay of 227 Ac and the contents of 226 Ra ,224 Ra w hich generates 222 Rn ,220 Rn to affect the purity of actinide in this source were analyzed after 227 Ac in radioactive equilibrium with its daughter nuclides . The γ‐ray energy used for the determination of these daughter nuclides of 227 Ac are 235.97 ,256.25 keV for 227 Th , 154.21 keV for 223Ra ,401.81 keV for 219Rn ,and 351.059 keV for 211Bi .Through the analysis ,the results are acquired that their activities are (1 069 ± 3 ) , (1 079 ± 5 ) , (1 095 ± 13) ,(1 096 ± 14) and (11 089 ± 4) Bq respectively ,and the average activity of solid 219 Rn source is (1 093 ± 8) Bq .The activities of 226 Ra and 224 Ra in this source are 5.12 Bq and 0.433 Bq respectively

  4. 77 FR 62316 - Holiday CVS, L.L.C., d/b/a CVS/Pharmacy Nos. 219 and 5195; Decision and Order

    Science.gov (United States)

    2012-10-12

    ... Justice Drug Enforcement Administration Holiday CVS, L.L.C., d/b/a CVS/Pharmacy Nos. 219 and 5195... Administration [Docket Nos. 12-37 and 12-38] Holiday CVS, L.L.C., d/b/a CVS/Pharmacy Nos. 219 and 5195; Decision... pharmacy than the ALJ did. Respondents argue that their dispensings of the prescriptions issued by...

  5. 77 FR 62346 - Holiday CVS, L.L.C., d/b/a CVS/Pharmacy Nos. 219 and 5195; Denial of Request for Redactions

    Science.gov (United States)

    2012-10-12

    .../a CVS/Pharmacy Nos. 219 and 5195; Denial of Request for Redactions On August 31, 2012, I issued a... Holiday CVS, L.L.C., d/b/a CVS/Pharmacy Nos. 219 and 5195 (hereinafter, Respondents). Prior to publication... manner in which information was obtained for Respondents' pharmacy information management...

  6. 32 CFR 219.103 - Assuring compliance with this policy-research conducted or supported by any Federal Department or...

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 2 2010-07-01 2010-07-01 false Assuring compliance with this policy-research... HUMAN SUBJECTS § 219.103 Assuring compliance with this policy—research conducted or supported by any Federal Department or Agency. (a) Each institution engaged in research which is covered by this policy...

  7. 48 CFR 1052.219-73 - Department of the Treasury Mentor-Protégé Program.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Department of the Treasury... DEPARTMENT OF THE TREASURY CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions and Clauses 1052.219-73 Department of the Treasury Mentor-Protégé Program. As described in DTAR...

  8. Expression of NMDA receptor and microRNA-219 in rats submitted to cerebral ischemia associated with alcoholism

    Directory of Open Access Journals (Sweden)

    Cristiane Iozzi Silva

    Full Text Available ABSTRACT Alcohol consumption aggravates injuries caused by ischemia. Many molecular mechanisms are involved in the pathophysiology of cerebral ischemia, including neurotransmitter expression, which is regulated by microRNAs. Objective: To evaluate the microRNA-219 and NMDA expression in brain tissue and blood of animals subjected to cerebral ischemia associated with alcoholism. Methods: Fifty Wistar rats were divided into groups: control, sham, ischemic, alcoholic, and ischemic plus alcoholic. The expression of microRNA-219 and NMDA were analyzed by real-time PCR. Results: When compared to the control group, the microRNA-219 in brain tissue was less expressed in the ischemic, alcoholic, and ischemic plus alcoholic groups. In the blood, this microRNA had lower expression in alcoholic and ischemic plus alcoholic groups. In the brain tissue the NMDA gene expression was greater in the ischemic, alcoholic, and ischemic plus alcoholic groups. Conclusion: A possible modulation of NMDA by microRNA-219 was observed with an inverse correlation between them.

  9. 48 CFR 52.219-27 - Notice of Total Service-Disabled Veteran-Owned Small Business Set-Aside.

    Science.gov (United States)

    2010-10-01

    ...-Disabled Veteran-Owned Small Business Set-Aside (MAY 2004) (a) Definition. Service-disabled veteran-owned... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Notice of Total Service... CONTRACT CLAUSES Text of Provisions and Clauses 52.219-27 Notice of Total Service-Disabled...

  10. MicroRNA-219-2-3p functions as a tumor suppressor in gastric cancer and is regulated by DNA methylation.

    Directory of Open Access Journals (Sweden)

    Huizi Lei

    Full Text Available BACKGROUND AIMS: Gastric cancer is the most frequent gastrointestinal tumor in adults and is the most lethal form of human cancer. Despite of the improvements in treatments, the underlying mechanism of gastric carcinogenesis is not well known. To define novel modulators that regulate susceptibility to tumorgenesis, we focused on miR-219-2-3p. METHODS: Quantitative RT-PCR was employed to investigate the level of miR-219-2-3p in gastric cancer (GC tissues (n = 113 and their matched adjacent normal tissues (n = 113. In vitro cell proliferation, apoptosis assays, cell migration, and invasion assays were performed to elucidate biological effects of miR-219-2-3p. Since silencing of miRNA by promoter CpG island methylation may be an important mechanism in tumorgenesis, GC cells were treated with 5-aza-2'-deoxycytidine and trichostatin A, and expression changes of miR-219-2-3p were subsequently examined by quantitative RT-PCR. Finally, the methylation status of CpG island upstream of miR-219-2-3p was analyzed by methylation-specific PCR in GC tissues (n = 22. RESULTS: miR-219-2-3p was down-regulated in GC and cell lines. In addition, the experiments documented the lower expression of miR-219-2-3p in GC specimens with higher grade and later stage tumors. Meanwhile, miR-219-2-3p exerted antiproliferative, proapoptotic, and antimetastatic roles and reduced levels of p-ERK1/2 in GC cells. Furthermore, 5-aza-2'-deoxycytidine and trichostatin A increased the expression (~2 fold of miR-219-2-3p in GC cells. By methylation-specific PCR, DNA methylation in the upstream region of miR-219-2-3p was detected in both adjacent normal tissues and cancer tissues. As expected, the methylation level was considerably higher in the miR-219-2-3p down-regulated group than up-regulated group. CONCLUSIONS: miR-219-2-3p is potentially involved in gastric cancer progression and metastasis by regulating ERK1/2-related signal pathways, which may provide a novel therapeutic strategy

  11. Preparation of Rh[16aneS4-diol](211)At and Ir[16aneS4-diol](211)At complexes as potential precursors for astatine radiopharmaceuticals. Part I: Synthesis.

    Science.gov (United States)

    Pruszyński, Marek; Bilewicz, Aleksander; Zalutsky, Michael R

    2008-04-01

    The goal of this study was to evaluate a new approach that can be applied for labeling biomolecules with (211)At. Many astatine compounds that have been synthesized are unstable in vivo, providing motivation for seeking different (211)At labeling strategies. The approach evaluated in this study was to attach astatide anions to soft metal cations, which are also complexed by a bifunctional ligand. Ultimately, this complex could in principle be subsequently conjugated to a biomolecule with the proper selection of ligand functionality. We report here the attachment of (211)At(-) and *I(-) (*I = (131)I or (125)I) anions to the soft metal cations Rh(III) and Ir(III), which are complexed by the 1,5,9,13-tetrathiacyclohexadecane-3,11-diol (16aneS4-diol) ligand. Radioactive *I(-) anions were used for preliminary studies directed at the optimization of reaction conditions and to provide a baseline for comparison of results with (211)At. Four complexes Rh[16aneS4-diol]*I/(211)At and Ir[16aneS4-diol]*I/(211)At were synthesized in high yield in a one-step procedure, and the products were characterized mainly by paper electrophoresis and reversed-phase HPLC. The influences of time and temperature of heating and concentrations of metal cations and sulfur ligand 16aneS4-diol, as well as pH on the reaction yields were determined. Yields of about 80% were obtained when the quantities of Rh(III) or Ir(III) cations and 16aneS4-diol ligand in the solutions were 62.5 nmol and 250 nmol, respectively, and the pH ranged 3.0-4.0. Syntheses required heating for 1-1.5 h at 75-80 degrees C. The influence of microwave heating on the time and completeness of the complexation reaction was evaluated and compared with the conventional method of heating in an oil bath. Microwave synthesis accelerates reactions significantly. With microwave heating, yields of about 75% for Rh[16aneS4-diol](131)I and Ir[16aneS4-diol](131)I complexes were obtained after only 20 min exposure of the reaction mixtures to

  12. Te-free environmental materials of TixSb2.19Se applied in phase change memory

    Science.gov (United States)

    Zhu, Yueqin; Song, Sannian; Li, Le; Xie, Huaqing; Song, Zhitang; Liu, Bo; Wu, Junxing

    2016-10-01

    Environmental friendly Te-free phase change material of TixSb2.19Se was investigated for PCM application. As the important thermal properties, the crystallization temperature (Tc) and data retention for ten years for the best selected composition Ti0.34Sb2.19Se (TSS) are 234°C and 160‡C, respectively. Detection of the crystal structure of TSS by means of XRD, TEM and XPS reveals that the grains are more uniform compared with Ge2Sb2Te5 (GST). The Set and Reset operation voltages for TSS-based phase change memory devices are much lower than those of conventional GST-based ones. Remarkably, the TSS device exhibits an extremely high phase change speed of 10 ns.

  13. Germination Response of MR 219 Rice Variety to Different Exposure Times and Periods of 2450 MHz Microwave Frequency

    OpenAIRE

    Daryush Talei; Alireza Valdiani; Mahmood Maziah; Mohammad Mohsenkhah

    2013-01-01

    Germination is a key process in plants' phenological cycles. Accelerating this process could lead to improvment of the seedling growth as well as the cultivation efficiency. To achieve this, the effect of microwave frequency on the germination of rice seeds was examined. The physiological feedbacks of the MR 219 rice variety in terms of seed germination rate (GR), germination percentage (GP), and mean germination time (MGT) were analyzed by exposing its seeds to 2450 MHz of microwave frequenc...

  14. {sup 18}F-labeling and biodistribution of the novel fluoro-quinolone antimicrobial agent, trovafloxacin (CP 99,219)

    Energy Technology Data Exchange (ETDEWEB)

    Babich, John W.; Rubin, Robert H.; Graham, Wendy A.; Wilkinson, Robert A.; Vincent, John; Fischman, Alan J

    1996-11-01

    [{sup 18}F]CP 99,219 [(1{alpha},5{alpha},6{alpha})-7-(6-amino-3-azabicyclo [3.1.0]hex-3-yl)-1-(2,4-difluorophenyl)-6-fluoro-1,4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid] was prepared by {sup 18}F for {sup 19} exchange followed by reverse-phase HPLC purification. Studies of the effects of reaction time and temperature on {sup 18}F incorporation demonstrated that heating 1.0 mg of CP 99,219 in 0.5 cc of DMSO with 4.5 mg of K{sub 2}CO{sub 3} and 24 mg of Kryptofix for 15 min at 160 deg. C results in the optimal compromise between radiochemical yield and purity. This method routinely provides radiochemical yields of 15-30% [EOS] with radiochemical purities of >97%. Varying the concentration of CP 99,219 in the reaction mixture had no effect on yield. Biodistribution studies in rats demonstrated that significant concentrations of drug accumulate in most tissues. The tissues with the highest concentrations of drug were intestine, liver, kidney, and stomach.

  15. INFERIOR TURBINECTOMY FOR NASAL OBSTRUCTION-STUDY O F 219 CASES

    Directory of Open Access Journals (Sweden)

    Santhosh

    2013-03-01

    Full Text Available ABSTRACT: OBJECTIVE : To determine the success rate of inferior turbine ctomy for nasal obstruction. To study complications of inferior turb inectomy. To study the histopathological changes in the inferior turbinate specimens. METHOD : This prospective, single blinded, randomized study of 219 consecutive patients carried out in two tertiary le vel centres from January 2010 to October 2011. The patients were asse ssed preoperatively and postoperatively both subjectively and objectively. The patients who were refractory to the directed conservative treatment for chronic nasal obstruction underwent i nferior turbinectomy on both sides and septoplasty if required. The inferior turbinectomy spe cimen was sent for histopathological examination. NOSE Questionnaires were used for subj ective assessment and rigid nasal endoscopy used for objective assessment. Follow up do ne at 1 week, 1 month and 6 months after surgery. Friedman test applied for assessment o f the improvement. RESULTS : 92 % (n=203 of patients relieved of nasal obstruction fo r which they approached. The improvement is statistically significant both subjectively and objectively. The common complications in present study is postoperative nasal synechia which o ccurred in 5% (n=10. Bleeding occurred in 4%(n=8. Dryness and crusting occurred in 2%(n=4 and foul odour in 2% (n=4. The present study also showed that most common cause for turbinate enlargement is chronic nonspecific inflammatory hypertrophy followed by aller gic turbinate hypertrophy. CONCLUSION : -The results show that inferior turbinectomy is t he good method of achieving relief from the nasal obstruction with minimal morb idity. Histopathological examination showed that most common cause of turbinate enlargem ent is chronic non specific turbinate hypertrophy and it proves beyond doubt that unnecessa ry excessive antiallergic treatment should be avoided in patients with chronic nasal obs truction KEY WORDS: inferior

  16. Association between apolipoprotein E promoter-219G/T polymorphism and total cholesterol level in patients with Alzheimer disease

    Institute of Scientific and Technical Information of China (English)

    Fang Liu; Xiao Sun; Jing Wang; Yan Kong; Li Cui; Xiangdang Shi

    2006-01-01

    BACKGROUND: Many researches have suggested that apolipoprotein E (APOE) and total cholesterol metabolism are closely related with dementia. In the supposed theory, 219 site of APOE promoter region is near gene coding region, so its polymorphism may result in the abnormality of APOE gene and protein expression,and finally lead to dementia.OBJECTIVE: To observe the association between APOE promoter-219G/T polymorphisms with serum total cholesterol in patients with Alzheimer disease, and compare it with non-dementia people.DESIGN: Case-control, comparative observation.SETTING: Department of Neurology, Fengtian Hospital of Shenyang Medical College.PARTICIPANTS: Fifty-five dementia patients including 27 males and 28 females aged (66±3) years and treated in the Department of Neurology, Fengtian Hospital were selected from January 2002 to December 2005 as the Alzheimer disease group. They all diagnosed according to the DSM- Ⅳ diagnostic criteria of Alzheimer disease instituted by American Psychiatry Association in 1994. Meanwhile, 44 none-dementia patients including 21 males and 23 females aged (66±3) years were selected from other clinical departments of Fengtian Hospital as control group. All the participants were informed the detection and agreed.METHODS: Genomic DNA was extracted from the peripheral blood of all subjects, then "NEST"PCR, DNA sequence and enzyme digestion were adopted to detect the expression of APOE promoter-219 polymorphism,following by biomedical statistics analysis based on the clinical total cholesterol level.MAIN OUTCOME MEASURES: Polymorphism of APOEpromoter-219 G/T and total cholesterol level.RESULTS: All 55 dementia patients and 44 non-dementia ones were involved in the result analysis. ①Allele and genotype frequency: The T allele frequency of the Alzheimer disease group was significantly higher than that in the control group [88.2% (97/110), 54.5% (48/88)], while G allele frequency was remarkably lower than that in the control group [11

  17. 2,19-二十二酮的新合成方法%A novel synthesis of long-chained acyclic diketone 2, 19-eicosanedione

    Institute of Scientific and Technical Information of China (English)

    吴新亮; 郭媛; 张斌; 史真

    2005-01-01

    以邻苯二胺和1,18-十八二酸为原料,经二苯并咪唑盐与格利雅试剂的加成-水解反应,合成出了长链二酮--2,19-二十二酮.同时,研究了合成2,19-二十二酮的最佳反应条件,并对其反应机理进行了讨论.

  18. The beneficial endophyte Trichoderma hamatum isolate DIS 219b promotes growth and delays the onset of the drought response in Theobroma cacao.

    Science.gov (United States)

    Bae, Hanhong; Sicher, Richard C; Kim, Moon S; Kim, Soo-Hyung; Strem, Mary D; Melnick, Rachel L; Bailey, Bryan A

    2009-01-01

    Theobroma cacao (cacao) is cultivated in tropical climates and is exposed to drought stress. The impact of the endophytic fungus Trichoderma hamatum isolate DIS 219b on cacao's response to drought was studied. Colonization by DIS 219b delayed drought-induced changes in stomatal conductance, net photosynthesis, and green fluorescence emissions. The altered expression of 19 expressed sequence tags (ESTs) (seven in leaves and 17 in roots with some overlap) by drought was detected using quantitative real-time reverse transcription PCR. Roots tended to respond earlier to drought than leaves, with the drought-induced changes in expression of seven ESTs being observed after 7 d of withholding water. Changes in gene expression in leaves were not observed until after 10 d of withholding water. DIS 219b colonization delayed the drought-altered expression of all seven ESTs responsive to drought in leaves by > or = 3 d, but had less influence on the expression pattern of the drought-responsive ESTs in roots. DIS 219b colonization had minimal direct influence on the expression of drought-responsive ESTs in 32-d-old seedlings. By contrast, DIS 219b colonization of 9-d-old seedlings altered expression of drought-responsive ESTs, sometimes in patterns opposite of that observed in response to drought. Drought induced an increase in the concentration of many amino acids in cacao leaves, while DIS 219b colonization caused a decrease in aspartic acid and glutamic acid concentrations and an increase in alanine and gamma-aminobutyric acid concentrations. With or without exposure to drought conditions, colonization by DIS 219b promoted seedling growth, the most consistent effects being an increase in root fresh weight, root dry weight, and root water content. Colonized seedlings were slower to wilt in response to drought as measured by a decrease in the leaf angle drop. The primary direct effect of DIS 219b colonization was promotion of root growth, regardless of water status, and an

  19. miR-219基因及其靶基因CAMK2G多态性与精神分裂症的关联研究%Association study of the polymorphisms in miR-219 gene and its target gene CAMK2G with schizophrenia

    Institute of Scientific and Technical Information of China (English)

    张燕霞; 汪栋祥; 李华芳; 傅迎美; 禹顺英

    2013-01-01

    Objectives This study aims to determine the potential association between polymorphisms in miR-219 gene and its target gene CAMK2G and schizophrenia. Methods Two SNPs (rs 107822 in miR-219 and rs2306327 in CAMK2G)were selected and genotyped by the TaqMan genotyping assay in a case-control study with 1041 schizophrenia cases and 953 healthy controls in Chinese Han population. Secondary structure of miR-219 with rs 107822 was constructed via the CentroidFold software. Results The allele frequency distribution of rs 107822 was statistically different between schizophrenia and healthy controls (χ2=7.33, P=0.007). Logistic regression analyses showed that the additive inheritance model was the best model for the gennotyping data of rs 107822 (P=0.0072). Individuals who carried the C allele were associated with significantly decreased risk of developing schizophrenia (OR=0.84, 95 % CI=0.74~ 0.95). Structure prediction by software found that secondary structure of miR-219 primary trancript (pri-miR-219) was changed when the T allele at rs 107822 was mutated to Callele. No statistical difference was found between cases and controls with regard to the allele or genotype distribution of rs2306327 .Conclusions These findings suggest that polymorphism rs l07822 in miR-219 gene may be associated with schizophrenia in the Chinese Han population.%目的 探讨微小核糖核苷酸-219(microRNA-219,miR-219)及其靶基因钙离子/钙调蛋白依赖性蛋白激酶Ⅱγ(Ca2+/calmodulin-dependent protein kinase Ⅱ gamma,CAMK2G)多态性与精神分裂症的关系. 方法 采用TaqMan探针基因分型技术在中国汉族人群中对1041例精神分裂症患者和953例正常对照者进行miR-219基因rs107822和CAMK2G基因rs2306327的分型.利用二级结构预测软件CentroidFold预测rs107822对miR-219二级结构影响.结果 miR-219基因rs107822多态的等位基因分布在患者组与正常对照组之间差异有统计学意义(x2=7.33,P=0.007);

  20. Comparative in vitro activities of trovafloxacin (CP-99,219) against 445 gram-positive isolates from patients with endocarditis and those with other bloodstream infections

    NARCIS (Netherlands)

    H.P. Endtz (Hubert); J.W. Mouton (Johan); J.G. den Hollander (Jan); N.P.W.C.J. van den Braak (Nicole); H.A. Verbrugh (Henri)

    1997-01-01

    textabstractThe in vitro activity of trovafloxacin (CP-99,219), a new fluoroquinolone, was compared with the in vitro activities of other commonly used quinolones and other antimicrobial agents against 445 gram-positive microorganisms isolated between 1986 and 1995 from

  1. Investigation and analysis on occupational impairment state in 219 firemen%某市219名消防员职业损伤情况调查分析

    Institute of Scientific and Technical Information of China (English)

    牛素玲

    2011-01-01

    目的 了解消防员职业损伤情况及其影响因素,为完善防护措施提供依据.方法 采用访谈、座谈和问卷调查等方法,对某市3个消防中队共219名消防员进行调查.结果 消防员存在训练致伤、火场致伤、装备因素致伤和心理应激等4大类职业损伤,问题较为突出的是训练伤中的腿部拉伤和警铃刺激致心理紧张,分别占调查总人数的55.7%和64.2%.3队之间职业损伤率存在一定差异(P<0.05),医学知识培训可减少消防员职业损伤.结论 科学进行消防员的专业训练,科学配置个体防护装备,建立医学知识培训制度,定期进行消防员的医学知识培训和职业健康监护,有助于减少消防员职业损伤.%Objective To understand the current status of occupational injuries of firefighters and its influencing factors, in order to provide reference for improving the protection measures. Methods 219 firefighter respondents from 3 fire departments in a certain city were investigated by in-depth interviews, group discussions and survey questionnaires. Results Based on the cause of injury, the injuries of firefighters could be categorized into 4 groups: training injuries, firefighting injuries, equipment-caused injuries and mental stress groups. Calf muscle strain of training injuries and psychological stress caused by alarm bell were two most outstanding problems, accounting for 55.7% and 64.2% respectively. Statistical significant differences were found among 3 teams (P < 0.05). Basic medical training was helpful to reduce and prevent occupational injuries. Conclusion To help reduce the occupational injuries for firefighters, much more efforts should be devoted take scientific training me-thods, to configure individual protective equipment, to establish medical knowledge training system and to take regular occupational health surveillance for them.

  2. 微小RNA-219-5p在肝细胞肝癌中的表达及其与乙醇的关系%Expression of microRNA-219-5p in hepatocellular carcinoma and its relationship with alcohol

    Institute of Scientific and Technical Information of China (English)

    李辉; 曹会存; 刘诗义; 刘健; 曹广劭; 赵晓阳

    2015-01-01

    Objective To study the roles of microRNA (miRNA,miR)-219-5p in the pathogenesis of hepatocellular carcinoma (HCC) and its relationship with alcohol and clinicopathological features.Methods The expression of miR-219-5p in 120 cases of HCC tissue samples was detected by real-time fluorescent quantitative polymerase chain reaction (FQ-PCR),and its relationship with alcohol and clinicopathological features was analyzed.Results (1) The expression of miR-219-5p was decreased significantly in those cancers tumors with diameter > 5 cm,worse tissue differentiation and heavy drinking (x2 =10.550,3.956,and 6.061 respectively,P < 0.01);(2) The logistic regression analysis revealed thaat a history of heavy drinking was one of the major risk factors of down-regulated miR-219-5p expression level [95% confidence interval (CI):1.521-17.635,P <0.05);(3) In the Cox regression model,the patients with the down-regulated miR-219-5p expression levels had high risk of death,and drinking,positive alpha fetal protein (AFP),chronic liver disease and larger tumor further increased the risk for death (P < 0.05).Conclusion It is believed that the expression of miR-219-5p,serum AFP-positive,tumor size,and chronic liver disease are independent risk factors for survival of patients with HCC,while heavy drinking consumption can further amplify the effects.%目的 观察微小RNA(miRNA,miR)-219-5p与乙醇、临床病理特征的关系及其在肝细胞肝癌(HCC)发生发展中的作用.方法 采用实时荧光定量聚合酶链反应(FQ-PCR)法对120例HCC患者组织中的miR-219-5p的表达进行检测,并比较其与饮酒、临床病理特征之间关系.结果 (1)肿瘤瘤体>5 cm、组织分化差以及大量饮酒者miR-219-5p的表达显著降低(x2=10.550、3.956、6.061,P<0.05);(2)在Logistic回归分析中,大量饮酒史是miR-219-5p表达水平下降的主要危险因素之一[95%可信区间(CI):1.521 ~ 17.635,P<0.05];(3)在Cox回归模型中,miR-219-5p表达水

  3. Immunophenotypes and Cytogenetic Alterations in 219 Cases of Diffuse Large B-cell Lymphoma%219例弥漫性大B 细胞淋巴瘤免疫表型及遗传学特征分析

    Institute of Scientific and Technical Information of China (English)

    管冰心; 潘毅; 房爱菊; 梁艳; 霍颖颖; 孙保存; 王华庆; 付凯; 孟斌

    2012-01-01

    Objective: To investigate the immunophenotypes, subtypes based on Hans algorithm, and alterations of Bcl-2 and Bcl-6 gene in diffuse large B-cell lymphoma ( DLBCL) from Chinese patients. Methods: The expression of CD10, BCL-6, MUM1, BCL-2, Ki67 and other markers were detected by immunohistochemistry in tissue microarrays of 219 DLBCL cases. Hans algorithm was applied to classify DLBCL into GCB and non-GCB subtypes. Interphase fluorescence in situ hybridization ( FISH ) was used to detect the incidence of Bcl-2 and Bcl-6 gene alterations. Other seven studies published in the last two years on DLBCL from China were collected and analyzed. Results: (1) This study: ① of 219 DLBCL cases, non-GCB subtype ( 165 cases, 75.3 % ) was significantly more common than GCB subtype ( 54 cases, 24.7 %)(P< 0.001). ② Bcl-2 gene alteration was detected in 49 cases (25.8 %), including 5 cases with the t (14 ; 18) (2.6 %) which all existed in GCB subtype, and 44 cases of Bcl-2 amplification ( 23.2 % ) which existed in GCB subtype in 4 cases ( 8.5 % ) and in non-GCB subtype in 40 cases (28.0 %){P = 0.013). ③ Bcl-6 gene rearrangement was detected in 42 cases (22.1 %), which was in GCB in 7 cases (14.9 % ) and was in non-GCB in 35 cases (24.5 % ) (P = 0.189). ④ a significant negative correlation between Bcl-2 gene amplification and Bcl-6 gene rearrangement was seen (r = - 0.179 6, P = 0.016 8). Amongst 5 cases having the t (14 ; 18) translocation, 2 cases accompanied by Bcl-6 gene rearrangement. Forty-nine cases with Bcl-2 gene alterations including translocation and amplification were all but one expressing BCL-2 protein, and there was no significant association between Bcl-6 gene rearrangement and BCL-6 protein expression ( P = 0.726 ). ⑤ there was no significant difference between nodal and extranodal DLBCLs in immunophenotypes, subtypes based on Hans algorithm, and Bcl-2 and Bcl-6 gene alterations (P = 0.462, P = 0.426 and P = 0.167). (2) Comprehensive analysis of eight

  4. Germination response of MR 219 rice variety to different exposure times and periods of 2450 MHz microwave frequency.

    Science.gov (United States)

    Talei, Daryush; Valdiani, Alireza; Maziah, Mahmood; Mohsenkhah, Mohammad

    2013-01-01

    Germination is a key process in plants' phenological cycles. Accelerating this process could lead to improvment of the seedling growth as well as the cultivation efficiency. To achieve this, the effect of microwave frequency on the germination of rice seeds was examined. The physiological feedbacks of the MR 219 rice variety in terms of seed germination rate (GR), germination percentage (GP), and mean germination time (MGT) were analyzed by exposing its seeds to 2450 MHz of microwave frequency for one, four, seven, and ten hours. It was revealed that exposing the seeds to the microwave frequency for 10 hours resulted in the highest GP. This treatment led to 100% of germination after three days with a mean germination time of 2.1 days. Although the other exposure times of microwave frequency caused the moderate effects on germination with a GP(a3) ranged from 93% to 98%, they failed to reduce the MGT(a3). The results showed that ten-hour exposure times of microwave frequency for six days significantly facilitated and improved the germination indices (primary shoot and root length). Therefore, the technique is expected to benefit the improvement of rice seed germination considering its simplicity and efficacy in increasing the germination percentage and rate as well as the primary shoot and root length without causing any environmental toxicity.

  5. Germination Response of MR 219 Rice Variety to Different Exposure Times and Periods of 2450 MHz Microwave Frequency

    Directory of Open Access Journals (Sweden)

    Daryush Talei

    2013-01-01

    Full Text Available Germination is a key process in plants' phenological cycles. Accelerating this process could lead to improvment of the seedling growth as well as the cultivation efficiency. To achieve this, the effect of microwave frequency on the germination of rice seeds was examined. The physiological feedbacks of the MR 219 rice variety in terms of seed germination rate (GR, germination percentage (GP, and mean germination time (MGT were analyzed by exposing its seeds to 2450 MHz of microwave frequency for one, four, seven, and ten hours. It was revealed that exposing the seeds to the microwave frequency for 10 hours resulted in the highest GP. This treatment led to 100% of germination after three days with a mean germination time of 2.1 days. Although the other exposure times of microwave frequency caused the moderate effects on germination with a GPa3 ranged from 93% to 98%, they failed to reduce the MGTa3. The results showed that ten-hour exposure times of microwave frequency for six days significantly facilitated and improved the germination indices (primary shoot and root length. Therefore, the technique is expected to benefit the improvement of rice seed germination considering its simplicity and efficacy in increasing the germination percentage and rate as well as the primary shoot and root length without causing any environmental toxicity.

  6. Outbreak of drug-resistant Acinetobacter baumannii ST219 caused by oral care using tap water from contaminated hand hygiene sinks as a reservoir.

    Science.gov (United States)

    Umezawa, Kazuo; Asai, Satomi; Ohshima, Toshio; Iwashita, Hideo; Ohashi, Maya; Sasaki, Mika; Kaneko, Akihiro; Inokuchi, Sadaki; Miyachi, Hayato

    2015-11-01

    An outbreak of amikacin- and ciprofloxacin-resistant Acinetobacter baumannii ST219 in Tokai University hospital's emergency intensive care unit was caused by its colonization in water systems and subsequent spread through oral care using tap water. The outbreak was successfully controlled after replacement of the water system and implementation as of daily cleaning of water taps and oral care with a dry method. It is important to strictly manage the water system in critical care areas.

  7. 76 FR 70336 - Airworthiness Directives; Rolls-Royce plc RB211-524G2-19; -524G2-T-19; -524G3-19; -524G3-T-19...

    Science.gov (United States)

    2011-11-14

    ... plc RB211-524G2-19; -524G2- T-19; -524G3-19; -524G3-T-19; 524H2-19; -524H2-T-19; -524H-36; and - 524H..., 2011. The Director of the Federal Register approved the incorporation by reference of Rolls-Royce plc... Information Rolls-Royce plc has issued Rolls-Royce plc Alert Service Bulletin No. RB.211-73-AG054, Revision...

  8. Infection of domestic dogs in peru by zoonotic bartonella species: a cross-sectional prevalence study of 219 asymptomatic dogs.

    Directory of Open Access Journals (Sweden)

    Pedro Paulo V P Diniz

    Full Text Available Bartonella species are emerging infectious organisms transmitted by arthropods capable of causing long-lasting infection in mammalian hosts. Among over 30 species described from four continents to date, 15 are known to infect humans, with eight of these capable of infecting dogs as well. B. bacilliformis is the only species described infecting humans in Peru; however, several other Bartonella species were detected in small mammals, bats, ticks, and fleas in that country. The objective of this study was to determine the serological and/or molecular prevalence of Bartonella species in asymptomatic dogs in Peru in order to indirectly evaluate the potential for human exposure to zoonotic Bartonella species. A convenient sample of 219 healthy dogs was obtained from five cities and three villages in Peru. EDTA-blood samples were collected from 205 dogs, whereas serum samples were available from 108 dogs. The EDTA-blood samples were screened by PCR followed by nucleotide sequencing for species identification. Antibodies against B. vinsonii berkhoffii and B. rochalimae were detected by IFA (cut-off of 1∶64. Bartonella DNA was detected in 21 of the 205 dogs (10%. Fifteen dogs were infected with B. rochalimae, while six dogs were infected with B. v. berkhoffii genotype III. Seropositivity for B. rochalimae was detected in 67 dogs (62%, and for B. v. berkhoffii in 43 (40% of the 108 dogs. Reciprocal titers ≥1∶256 for B. rochalimae were detected in 19% of dogs, and for B. v. berkhoffii in 6.5% of dogs. This study identifies for the first time a population of dogs exposed to or infected with zoonotic Bartonella species, suggesting that domestic dogs may be the natural reservoir of these zoonotic organisms. Since dogs are epidemiological sentinels, Peruvian humans may be exposed to infections with B. rochalimae or B. v. berkhoffii.

  9. Infection of domestic dogs in peru by zoonotic bartonella species: a cross-sectional prevalence study of 219 asymptomatic dogs.

    Science.gov (United States)

    Diniz, Pedro Paulo V P; Morton, Bridget A; Tngrian, Maryam; Kachani, Malika; Barrón, Eduardo A; Gavidia, Cesar M; Gilman, Robert H; Angulo, Noelia P; Brenner, Elliott C; Lerner, Richard; Chomel, Bruno B

    2013-01-01

    Bartonella species are emerging infectious organisms transmitted by arthropods capable of causing long-lasting infection in mammalian hosts. Among over 30 species described from four continents to date, 15 are known to infect humans, with eight of these capable of infecting dogs as well. B. bacilliformis is the only species described infecting humans in Peru; however, several other Bartonella species were detected in small mammals, bats, ticks, and fleas in that country. The objective of this study was to determine the serological and/or molecular prevalence of Bartonella species in asymptomatic dogs in Peru in order to indirectly evaluate the potential for human exposure to zoonotic Bartonella species. A convenient sample of 219 healthy dogs was obtained from five cities and three villages in Peru. EDTA-blood samples were collected from 205 dogs, whereas serum samples were available from 108 dogs. The EDTA-blood samples were screened by PCR followed by nucleotide sequencing for species identification. Antibodies against B. vinsonii berkhoffii and B. rochalimae were detected by IFA (cut-off of 1∶64). Bartonella DNA was detected in 21 of the 205 dogs (10%). Fifteen dogs were infected with B. rochalimae, while six dogs were infected with B. v. berkhoffii genotype III. Seropositivity for B. rochalimae was detected in 67 dogs (62%), and for B. v. berkhoffii in 43 (40%) of the 108 dogs. Reciprocal titers ≥1∶256 for B. rochalimae were detected in 19% of dogs, and for B. v. berkhoffii in 6.5% of dogs. This study identifies for the first time a population of dogs exposed to or infected with zoonotic Bartonella species, suggesting that domestic dogs may be the natural reservoir of these zoonotic organisms. Since dogs are epidemiological sentinels, Peruvian humans may be exposed to infections with B. rochalimae or B. v. berkhoffii.

  10. Cyto-histological correlation of 219 patients submitted to surgical treatment due to diagnosis of cervical intraepithelial neoplasia

    Directory of Open Access Journals (Sweden)

    Sheila Jorge Adad

    1999-03-01

    Full Text Available CONTEXT: Cervical cytology continues to be the most appropriate method for investigating cervical neoplasia and its precursors. Greater diagnostic acuity is obtained by combining cytology, colposcopy and guided biopsy methods. OBJECTIVE: To analyze the diagnostic acuity of cyto- and histopathological exams and causes of diagnostic error. DESIGN: Retrospective study. SETTING: A public tertiary referral center. SAMPLE: Reports on 219 patients submitted to cone biopsy and/or hysterectomy due to diagnosis of cervical intraepithelial neoplasia (CIN in the period between January 1982 and March 1997 were reviewed, comparing. MAIN MEASUREMENTS: cytological and histological exams (guided biopsy and surgically-removed tissue. In cases of discordance, the cyto- and histological preparations were reviewed to try to evaluate the causes of errors. RESULTS: In 193 cases (88.1% there was cyto-histological agreement but none in 26 (11.9%. Review of the discordant cases showed that in 2 (0.9% there was invasion of the stromata to a depth greater than 3mm, and in 7 (3.2% microinvasion, unsuspected via cytology; in 2 (0.9% microinvasion was suspected via cytology but not confirmed by the final histological exam; and in 15 (6.8% there was disagreement about the degree of CIN. CONCLUSION: The principal causes of error in the cytological exam were the lack of reliable morphological criteria for microinvasion, absence of sampling of the squamocolumnar junction, and scarcity of neoplastic cells in the sample. As for the histological exam, the errors were related to inadequate technical processing and underestimation of focal lesions.

  11. Corrective Action Investigation Plan for Corrective Action Unit 219: Septic Systems and Injection Wells, Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    David A. Strand

    2005-01-01

    The Corrective Action Investigation Plan for Corrective Action Unit 219, Septic Systems and Injection Wells, has been developed in accordance with the ''Federal Facility Agreement and Consent Order'' (1996) that was agreed to by the State of Nevada, the U.S. Department of Energy, and the U.S. Department of Defense. The purpose of the investigation is to ensure that adequate data are collected to provide sufficient and reliable information to identify, evaluate, and select technically viable corrective actions. Corrective Action Unit 219 is located in Areas 3, 16, and 23 of the Nevada Test Site, which is 65 miles northwest of Las Vegas, Nevada. Corrective Action Unit 219 is comprised of the six Corrective Action Sites (CASs) listed below: (1) 03-11-01, Steam Pipes and Asbestos Tiles; (2) 16-04-01, Septic Tanks (3); (3) 16-04-02, Distribution Box; (4) 16-04-03, Sewer Pipes; (5) 23-20-01, DNA Motor Pool Sewage and Waste System; and (6) 23-20-02, Injection Well. These sites are being investigated because existing information on the nature and extent of potential contamination is insufficient to evaluate and recommend corrective action alternatives. Additional information will be obtained by conducting a corrective action investigation prior to evaluating corrective action alternatives and selecting the appropriate corrective action for each CAS. The results of the field investigation will support a defensible evaluation of viable corrective action alternatives that will be presented in the Corrective Action Decision Document.

  12. Dynamical decay process of {sup 219,} {sup 220}Ra{sup *} formed in {sup 10,} {sup 11}B+{sup 209}Bi reactions

    Energy Technology Data Exchange (ETDEWEB)

    Sawhney, G.; Sharma, M.K. [Thapar University, School of Physics and Materials Science, Punjab (India)

    2012-05-15

    The excitation functions for both the evaporation residue and fission have been calculated for {sup 10}B +{sup 209}Bi and {sup 11}B+{sup 209}Bi reactions forming compound systems {sup 219,220}Ra{sup *}, using the dynamical cluster-decay model (DCM) with effects of deformations and orientations of the nuclei included in it. In addition to this, the excitation functions for complete fusion (CF) are obtained by summing the fission cross-sections, neutron evaporation and charged particle evaporation residue cross-sections produced through the {alpha}xn and pxn (x = 2, 3, 4) emission channels for the {sup 219}Ra system at various incident centre-of-mass energies. Experimentally the CF cross-sections are suppressed and the observed suppression is attributed to the low binding energy of {sup 10,11}B which breaks up into charged fragments. The reported complete fusion (CF) and incomplete fusion (ICF) excitation functions for the {sup 219}Ra system are found to be nicely fitted by the calculations performed in the framework of DCM, without invoking a significant contribution from quasi-fission. Although DCM has been applied for a number of compound nucleus decay studies in the recent past, the same is being used here in reference to ICF and subsequent decay processes along with the CF process. Interestingly the main contribution to complete fusion cross-section comes from the fission cross-section at higher incident energies, which in DCM is found to consist of an asymmetric fission window, shown to arise due to the deformation and orientation effects of formation and decay fragments. (orig.)

  13. Characterization of the K2-19 Multiple-Transiting Planetary System via High-Dispersion Spectroscopy, AO Imaging, and Transit Timing Variations

    CERN Document Server

    Narita, Norio; Fukui, Akihiko; Hori, Yasunori; Sanchis-Ojeda, Roberto; Winn, Joshua N; Ryu, Tsuguru; Kusakabe, Nobuhiko; Kudo, Tomoyuki; Onitsuka, Masahiro; Delrez, Laetitia; Gillon, Michael; Jehin, Emmanuel; McCormac, James; Holman, Matthew; Izumiura, Hideyuki; Takeda, Yoichi; Tamura, Motohide; Yanagisawa, Kenshi

    2015-01-01

    K2-19 (EPIC201505350) is a unique planetary system in which two transiting planets with radii ~ 7 $R_{Earth}$ (inner planet b) and ~ 4 $R_{Earth}$ (outer planet c) have orbits that are nearly in a 3:2 mean-motion resonance. Here, we present results of ground-based follow-up observations for the K2-19 planetary system. We have performed high-dispersion spectroscopy and high-contrast adaptive-optics imaging of the host star with the HDS and HiCIAO on the Subaru 8.2m telescope. We find that the host star is relatively old (>8 Gyr) late G-type star ($T_{eff}$ ~ 5350 K, $M_s$ ~ 0.9 $M_{Sun}$, and $R_{s}$ ~ 0.9 $R_{Sun}$). We do not find any contaminating faint objects near the host star which could be responsible for (or dilute) the transit signals. We have also conducted transit follow-up photometry for the inner planet with KeplerCam on the FLWO 1.2m telescope, TRAPPISTCAM on the TRAPPIST 0.6m telescope, and MuSCAT on the OAO 1.88m telescope. We confirm the presence of transit-timing variations, as previously re...

  14. Corrective Action Decision Document/Closure Report for Corrective Action Unit 219: Septic Systems and Injection Wells, Nevada Test Site, Nevada, Rev. No.: 0

    Energy Technology Data Exchange (ETDEWEB)

    David Strand

    2006-05-01

    This Corrective Action Decision Document/Closure Report has been prepared for Corrective Action Unit (CAU) 219, Septic Systems and Injection Wells, in Areas 3, 16, and 23 of the Nevada Test Site, Nevada, in accordance with the ''Federal Facility Agreement and Consent Order'' (1996). Corrective Action Unit 219 is comprised of the following corrective action sites (CASs): (1) 03-11-01, Steam Pipes and Asbestos Tiles; (2) 16-04-01, Septic Tanks (3); (3) 16-04-02, Distribution Box; (4) 16-04-03, Sewer Pipes; (5) 23-20-01, DNA Motor Pool Sewage and Waste System; and (6) 23-20-02, Injection Well. The purpose of this Corrective Action Decision Document/Closure Report is to provide justification and documentation supporting the recommendation for closure of CAU 219 with no further corrective action beyond the application of a use restriction at CASs 16-04-01, 16-04-02, and 16-04-03. To achieve this, corrective action investigation (CAI) activities were performed from June 20 through October 12, 2005, as set forth in the CAU 219 Corrective Action Investigation Plan and Record of Technical Change No. 1. A best management practice was implemented at CASs 16-04-01, 16-04-02, and 16-04-03, and corrective action was performed at CAS 23-20-01 between January and April 2006. In addition, a use restriction will be applied to CASs 16-04-01, 16-04-02, and 16-04-03 to provide additional protection to Nevada Test Site personnel. The purpose of the CAI was to fulfill the following data needs as defined during the data quality objective (DQO) process: (1) Determine whether contaminants of concern (COCs) are present. (2) If COCs are present, determine their nature and extent. (3) Provide sufficient information and data to complete appropriate corrective actions. The CAU 219 dataset from the investigation results was evaluated based on the data quality indicator parameters. This evaluation demonstrated the quality and acceptability of the dataset for use in fulfilling

  15. Discovery of Eclipsing Binary Central Stars in the Planetary Nebulae M 3-16, H 2-29 and M 2-19

    CERN Document Server

    Miszalski, B; Moffat, A F J; Parker, Q A; Udalski, A

    2008-01-01

    Progress in understanding the formation and evolution of planetary nebulae (PN) has been restricted by a paucity of well-determined central star masses. To address this deficiency we aim to (i) significantly increase the number of known eclipsing binary central stars of PN (CSPN), and subsequently (ii) directly obtain their masses and absolute dimensions by combining their light-curve parameters with planned radial velocity data. Using photometric data from the third phase of the Optical Gravitational Lensing Experiment (OGLE) we have searched for periodic variability in a large sample of PN towards the Galactic Bulge using Fourier and phase-dispersion minimisation techniques. Among some dozen periodically variable CSPN found, we report here on three new eclipsing binaries: M 3-16, H 2-29 and M 2-19. We present images, confirmatory spectroscopy and light-curves of the systems.

  16. Leptin receptor isoform 219.1: an example of protein evolution by LINE-1-mediated human-specific retrotransposition of a coding SVA element.

    Science.gov (United States)

    Damert, Annette; Löwer, Johannes; Löwer, Roswitha

    2004-04-01

    Phylogenetically new insertions of repetitive sequences may contribute to genome evolution by altering the function of preexisting proteins. One example is the SVA sequence, which forms the C-terminal coding exon of the human leptin receptor isoform 219.1. Here, we report that the SVA insertion into the LEPR locus has occurred after divergence of humans and chimpanzees. The SVA element was inserted into a Hal-1/LINE element present in all monkeys and apes tested. Structural features point toward an integration event that was mediated by the L1 protein machinery acting in trans. Thus, our findings add evidence to the hypothesis that retrotransposition events are a driving force in genomic evolution and that the presence or absence of specific retroelements are one distinguishing feature that separates humans from chimpanzees.

  17. Determination of optimum welding parameters in connecting high alloyed X53CrMnNiN219 and X45CrSi93 steels by friction welding

    Indian Academy of Sciences (India)

    Mehmet Uzkut; Bekir Sadik Ünlü; Mustafa Akdağ

    2011-07-01

    In this study, different welding parameters were applied to two different steels with high alloys and mechanical and metallographical investigations are performed. Thus, the optimum welding parameters were determined for these materials and working conditions. 12.30 diameter steel bars made up of 1.4871 (X53CrMnNiN219) and 1.4718 (X45CrSi93) steel were used as experimental material. The material loss increased with increase in friction and rotating pressure. No fracture at the welding region was observed and the highest fracture energy was identified in B5 group. Based on micro hardness investigation; the hardness profile reached its minimum value at the welding region.

  18. Characterization of the K2-19 Multiple-transiting Planetary System via High-dispersion Spectroscopy, AO Imaging, and Transit Timing Variations

    Science.gov (United States)

    Narita, Norio; Hirano, Teruyuki; Fukui, Akihiko; Hori, Yasunori; Sanchis-Ojeda, Roberto; Winn, Joshua N.; Ryu, Tsuguru; Kusakabe, Nobuhiko; Kudo, Tomoyuki; Onitsuka, Masahiro; Delrez, Laetitia; Gillon, Michael; Jehin, Emmanuel; McCormac, James; Holman, Matthew; Izumiura, Hideyuki; Takeda, Yoichi; Tamura, Motohide; Yanagisawa, Kenshi

    2015-12-01

    K2-19 (EPIC201505350) is an interesting planetary system in which two transiting planets with radii ∼7 R⊕ (inner planet b) and ∼4 R⊕ (outer planet c) have orbits that are nearly in a 3:2 mean-motion resonance. Here, we present results of ground-based follow-up observations for the K2-19 planetary system. We have performed high-dispersion spectroscopy and high-contrast adaptive-optics imaging of the host star with the HDS and HiCIAO on the Subaru 8.2 m telescope. We find that the host star is a relatively old (≥8 Gyr) late G-type star (Teff ∼ 5350 K, Ms ∼ 0.9 M⊙, and Rs ∼ 0.9 R⊙). We do not find any contaminating faint objects near the host star that could be responsible for (or dilute) the transit signals. We have also conducted transit follow-up photometry for the inner planet with KeplerCam on the FLWO 1.2 m telescope, TRAPPISTCAM on the TRAPPIST 0.6 m telescope, and MuSCAT on the OAO 1.88 m telescope. We confirm the presence of transit timing variations (TTVs), as previously reported by Armstrong and coworkers. We model the observed TTVs of the inner planet using the synodic chopping formulae given by Deck & Agol. We find two statistically indistinguishable solutions for which the period ratios (Pc/Pb) are located slightly above and below the exact 3:2 commensurability. Despite the degeneracy, we derive the orbital period of the inner planet Pb ∼ 7.921 days and the mass of the outer planet Mc ∼ 20 M⊕. Additional transit photometry (especially for the outer planet) as well as precise radial-velocity measurements would be helpful to break the degeneracy and to determine the mass of the inner planet.

  19. Transient climate simulations of the deglaciation 21-9 thousand years before present; PMIP4 Core experiment design and boundary conditions

    Science.gov (United States)

    Ivanovic, Ruza; Gregoire, Lauren; Kageyama, Masa; Roche, Didier; Valdes, Paul; Burke, Andrea; Drummond, Rosemarie; Peltier, W. Richard; Tarasov, Lev

    2016-04-01

    The last deglaciation, which marked the transition between the last glacial and present interglacial periods, was punctuated by a series of rapid (centennial and decadal) climate changes. Numerical climate models are useful for investigating mechanisms that underpin the events, especially now that some of the complex models can be run for multiple millennia. We have set up a Paleoclimate Modelling Intercomparison Project (PMIP) working group to coordinate efforts to run transient simulations of the last deglaciation, and to facilitate the dissemination of expertise between modellers and those engaged with reconstructing the climate of the last 21 thousand years. Here, we present the design of a coordinated Core simulation over the period 21-9 thousand years before present (ka) with time varying orbital forcing, greenhouse gases, ice sheets, and other geographical changes. A choice of two ice sheet reconstructions is given. Additional focussed simulations will also be coordinated on an ad-hoc basis by the working group, for example to investigate the effect of ice sheet and iceberg meltwater, and the uncertainty in other forcings. Some of these focussed simulations will concentrate on shorter durations around specific events to allow the more computationally expensive models to take part. Ivanovic, R. F., Gregoire, L. J., Kageyama, M., Roche, D. M., Valdes, P. J., Burke, A., Drummond, R., Peltier, W. R., and Tarasov, L.: Transient climate simulations of the deglaciation 21-9 thousand years before present; PMIP4 Core experiment design and boundary conditions, Geosci. Model Dev. Discuss., 8, 9045-9102, doi:10.5194/gmdd-8-9045-2015, 2015.

  20. CHARACTERIZATION OF THE K2-19 MULTIPLE-TRANSITING PLANETARY SYSTEM VIA HIGH-DISPERSION SPECTROSCOPY, AO IMAGING, AND TRANSIT TIMING VARIATIONS

    Energy Technology Data Exchange (ETDEWEB)

    Narita, Norio; Hori, Yasunori; Kusakabe, Nobuhiko; Takeda, Yoichi; Tamura, Motohide [Astrobiology Center, 2-21-1 Osawa, Mitaka, Tokyo, 181-8588 (Japan); Hirano, Teruyuki [Department of Earth and Planetary Sciences, Tokyo Institute of Technology, 2-12-1 Ookayama, Meguro-ku, Tokyo 152-8551 (Japan); Fukui, Akihiko; Yanagisawa, Kenshi [Okayama Astrophysical Observatory, National Astronomical Observatory of Japan, Asakuchi, Okayama 719-0232 (Japan); Sanchis-Ojeda, Roberto [Department of Astronomy, University of California, Berkeley, CA 94720 (United States); Winn, Joshua N. [Department of Physics, and Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, Cambridge, MA 02139 (United States); Ryu, Tsuguru; Onitsuka, Masahiro [National Astronomical Observatory of Japan, 2-21-1 Osawa, Mitaka, Tokyo, 181-8588 (Japan); Kudo, Tomoyuki [Subaru Telescope, 650 North A’ohoku Place, Hilo, HI 96720 (United States); Delrez, Laetitia; Gillon, Michael; Jehin, Emmanuel [Institut d’Astrophysique et de Géophysique, Université de Liège, Allée du 6 Août 17, Bat. B5C, B-4000 Liège (Belgium); McCormac, James [Department of Physics, University of Warwick, Gibbet Hill Road, Coventry CV4 7AL (United Kingdom); Holman, Matthew [Smithsonian Astrophysical Observatory, 60 Garden Street, Cambridge, MA 02138 (United States); Izumiura, Hideyuki, E-mail: norio.narita@nao.ac.jp [SOKENDAI (The Graduate University for Advanced Studies), 2-21-1 Osawa, Mitaka, Tokyo, 181-8588 (Japan)

    2015-12-10

    K2-19 (EPIC201505350) is an interesting planetary system in which two transiting planets with radii ∼7 R{sub ⊕} (inner planet b) and ∼4 R{sub ⊕} (outer planet c) have orbits that are nearly in a 3:2 mean-motion resonance. Here, we present results of ground-based follow-up observations for the K2-19 planetary system. We have performed high-dispersion spectroscopy and high-contrast adaptive-optics imaging of the host star with the HDS and HiCIAO on the Subaru 8.2 m telescope. We find that the host star is a relatively old (≥8 Gyr) late G-type star (T{sub eff} ∼ 5350 K, M{sub s} ∼ 0.9 M{sub ⊙}, and R{sub s} ∼ 0.9 R{sub ⊙}). We do not find any contaminating faint objects near the host star that could be responsible for (or dilute) the transit signals. We have also conducted transit follow-up photometry for the inner planet with KeplerCam on the FLWO 1.2 m telescope, TRAPPISTCAM on the TRAPPIST 0.6 m telescope, and MuSCAT on the OAO 1.88 m telescope. We confirm the presence of transit timing variations (TTVs), as previously reported by Armstrong and coworkers. We model the observed TTVs of the inner planet using the synodic chopping formulae given by Deck and Agol. We find two statistically indistinguishable solutions for which the period ratios (P{sub c}/P{sub b}) are located slightly above and below the exact 3:2 commensurability. Despite the degeneracy, we derive the orbital period of the inner planet P{sub b} ∼ 7.921 days and the mass of the outer planet M{sub c} ∼ 20 M{sub ⊕}. Additional transit photometry (especially for the outer planet) as well as precise radial-velocity measurements would be helpful to break the degeneracy and to determine the mass of the inner planet.

  1. Transient climate simulations of the deglaciation 21-9 thousand years before present (version 1) - PMIP4 Core experiment design and boundary conditions

    Science.gov (United States)

    Ivanovic, Ruza F.; Gregoire, Lauren J.; Kageyama, Masa; Roche, Didier M.; Valdes, Paul J.; Burke, Andrea; Drummond, Rosemarie; Peltier, W. Richard; Tarasov, Lev

    2016-07-01

    The last deglaciation, which marked the transition between the last glacial and present interglacial periods, was punctuated by a series of rapid (centennial and decadal) climate changes. Numerical climate models are useful for investigating mechanisms that underpin the climate change events, especially now that some of the complex models can be run for multiple millennia. We have set up a Paleoclimate Modelling Intercomparison Project (PMIP) working group to coordinate efforts to run transient simulations of the last deglaciation, and to facilitate the dissemination of expertise between modellers and those engaged with reconstructing the climate of the last 21 000 years. Here, we present the design of a coordinated Core experiment over the period 21-9 thousand years before present (ka) with time-varying orbital forcing, greenhouse gases, ice sheets and other geographical changes. A choice of two ice sheet reconstructions is given, and we make recommendations for prescribing ice meltwater (or not) in the Core experiment. Additional focussed simulations will also be coordinated on an ad hoc basis by the working group, for example to investigate more thoroughly the effect of ice meltwater on climate system evolution, and to examine the uncertainty in other forcings. Some of these focussed simulations will target shorter durations around specific events in order to understand them in more detail and allow for the more computationally expensive models to take part.

  2. 乙醇、微小RNA-219-5p对肝癌细胞中聚糖蛋白3表达的影响%Effects of alcohol and microRNA-219-5p on proteoglycan 3 in hepatocellular carcinoma

    Institute of Scientific and Technical Information of China (English)

    李辉; 曹会存; 刘诗义; 刘健; 曹广劭; 赵晓阳

    2015-01-01

    Objective To observe the effects of alcohol and microRNA (miRNA)-219-5p on proteoglycan 3 (GPC3) in hepatocullular carcinoma (HCC).Methods Immunohistochemical staining method was used to detect the expression of 30 cases of normal liver tissues,120 cases of HCC tissues and corresponding para-concerous liver tissues.The relationship between GPC3 and clinical data of Han patients with HCC,and the inner link between GPC3 with alcohol and miRNA-219-5p were analyzed.Results The GPC3 positive expression was 75% in HCC tissues and 30% in para-cancerous tissues (x2 =74.348,P <0.01).No GPC3 expression was detected in normal liver tissues.The GPC3 expression was not related to age,positive hepatitis B surface antigen (HBsAg),history of chronic liver disease and tumor size [x2(HCC tissues) =1.800,0.533,1.140,0.568,P > 0.05;x2(para-cancerous tissues) =0.179,0,0,0.714,P > 0.05).The GPC3 positive expression rate was 100% in patients with heavy drinking,and that was 70% in non-heavy drinking patients.(x2 =8.000,P < 0.01),suggesting drinking behavior had a significant relevance with the GPC3 expression.Conclusion The occurrence of HCC is correlated with the low expression of miRAN-219 and high expression of GPC3 protein.At the same time,heavy drinking behavior can enlarge this effect.%目的 观察乙醇、微小RNA(miRNA)-219-5p对肝细胞肝癌(HCC)中聚糖蛋白3(GPC3)表达的影响.方法 采用免疫组织化学检测30例正常肝脏组织、120例HCC患者肝癌组织及相应癌旁组织标本中GPC3蛋白的表达水平,分析GPC3与HCC汉族临床资料之间的关系,探讨其与饮酒、miRNA-219-5p相关性.结果 GPC3在HCC组织中的阳性表达率为75%,在癌旁组织中其阳性表达率为30%,正常肝组织中未发现其阳性表达,3组比较差异有统计学意义(x2=74.348,P<0.01).在年龄、乙型肝炎表面抗原(HBsAg)阳性、慢性肝病病史以及肿瘤大小方面,GPC3表达均未受到影响[x2(肝癌组织)=1.800、0

  3. ø219.1/168.3 mm 气举反循环双壁钻具及其在大直径工程井中的应用%ø219.1/168.3 mm Air-lift RC Dual Wall Drilling Tools and Their Use in Large Diameter Drilling

    Institute of Scientific and Technical Information of China (English)

    熊亮; 袁志坚; 白领国; 彭桂湘; 耿建国

    2013-01-01

    Considering the shortcomings such as low efficiency, long construction period, high risk etc.of the commonly used large diameter drilling process which consists of direct circulation drilling and stepped reaming, a219.1/168.3 mm dual-wall, and168.3 mm internal flush drill pipes have been developed with the complete accessories, and successfully used to drilling a 1200 mm diameter , 651.2 m deep gas drainage well.The drilling tool is large in size, has high strength, and is connected with special threads.Field use indicates that the drilling tool has high tensile and torsional strength with good sealing.Compared with conventional drilling processes, the air-lift reverse circulation technique provides good cutting-carrying capacity, and increases the rate of penetrate by 74.3% with the quality borehole.In addition, drilling risk is greatly reduced owing to cleanliness of the borehole.%针对当前国内普遍采用“正循环回转钻进+分级扩孔”方法施工大直径工程井效率低、周期长、工程风险大等不足,研制了饱219.1/168.3 mm气举反循环双壁钻具和饱168.3 mm内平单壁钻具及配套附属器具,并成功应用于某直径1200 mm、深651.2 m的大口径瓦斯抽排井。该套钻具尺寸大,强度高,采用特殊螺纹连接。现场应用表明,钻具抗拉、抗扭强度高,密封性能好,应用气举反循环施工较传统工艺携岩效果好,机械钻速提高74.3%,井身质量优。此外,由于井内干净,钻井风险也得以大幅降低。

  4. Evaluation of Adenosine Triphosphate-Binding Cassette Transporter A1 (ABCA1) R219K and C-Reactive Protein Gene (CRP) +1059G/C Gene Polymorphisms in Susceptibility to Coronary Heart Disease.

    Science.gov (United States)

    Li, Jing-Fang; Peng, Dian-Ying; Ling, Mei; Yin, Yong

    2016-08-25

    BACKGROUND This meta-analysis investigated the correlation of ABCA1 R219K and C-Reactive Protein Gene (CRP) +1059G/C gene polymorphisms with susceptibility to coronary heart disease (CHD). MATERIAL AND METHODS We searched PubMed, Springer link, Wiley, EBSCO, Ovid, Wanfang database, VIP database, and China National Knowledge Infrastructure (CNKI) databases to retrieve published studies by keyword. Searches were filtered using our stringent inclusion and exclusion criteria. Resultant high-quality data collected from the final selected studies were analyzed using Comprehensive Meta-analysis 2.0 software. Eleven case-control studies involving 3053 CHD patients and 3403 healthy controls met our inclusion criteria. Seven studies were conducted in Asian populations, 3 studies were done in Caucasian populations, and 1 was in an African population. RESULTS Our major finding was that ABCA1 R219K polymorphism increased susceptibility to CHD in allele model (OR=0.729, 95% CI=0.559~0.949, P=0.019) and dominant model (OR=0.698, 95% CI=0.507~0.961, P=0.027). By contrast, we were unable to find any significant association between the CRP +1059G/C polymorphism and susceptibility to CHD (allele model: OR=1.170, 95% CI=0.782~1.751, P=0.444; dominant model: OR=1.175, 95% CI=0.768~1.797, P=0.457). CONCLUSIONS This meta-analysis provides convincing evidence that polymorphism of ABCA1 R219K is associated with susceptibility to CHD while the CRP +1059G/C polymorphism appears to have no correlation with susceptibility to CHD.

  5. Potential for Cell-Transplant Therapy with Human Neuronal Precursors to Treat Neuropathic Pain in Models of PNS and CNS Injury: Comparison of hNT2.17 and hNT2.19 Cell Lines

    Directory of Open Access Journals (Sweden)

    Mary J. Eaton

    2012-01-01

    Full Text Available Effective treatment of sensory neuropathies in peripheral neuropathies and spinal cord injury (SCI is one of the most difficult problems in modern clinical practice. Cell therapy to release antinociceptive agents near the injured spinal cord is a logical next step in the development of treatment modalities. But few clinical trials, especially for chronic pain, have tested the potential of transplant of cells to treat chronic pain. Cell lines derived from the human neuronal NT2 cell line parentage, the hNT2.17 and hNT2.19 lines, which synthesize and release the neurotransmitters gamma-aminobutyric acid (GABA and serotonin (5HT, respectively, have been used to evaluate the potential of cell-based release of antinociceptive agents near the lumbar dorsal (horn spinal sensory cell centers to relieve neuropathic pain after PNS (partial nerve and diabetes-related injury and CNS (spinal cord injury damage in rat models. Both cell lines transplants potently and permanently reverse behavioral hypersensitivity without inducing tumors or other complications after grafting. Functioning as cellular minipumps for antinociception, human neuronal precursors, like these NT2-derived cell lines, would likely provide a useful adjuvant or replacement for current pharmacological treatments for neuropathic pain.

  6. 49 CFR 372.219 - Washington, DC

    Science.gov (United States)

    2010-10-01

    ... and is comprised of all points as follows: (a) The municipality of Washington, D.C., itself; (b) All... Manassas, VA, and the City of Manassas Park, VA. (d) All of any municipality any part of which is within... municipality wholly surrounded, or so surrounded except for a water boundary, by the municipality of...

  7. 12 CFR 219.3 - Cost reimbursement.

    Science.gov (United States)

    2010-01-01

    ... that the financial institution use programming or other higher level technical services of a computer... of extracting electronically stored records, based on computer time and necessary supplies; however, personnel time for computer searches may be paid for at the rates set for computer support...

  8. 22 CFR 219.103 - Definitions.

    Science.gov (United States)

    2010-04-01

    ... following body systems: Neurological; musculoskeletal; special sense organs; respiratory, including speech organs; cardiovascular; reproductive; digestive; genitourinary; hemic and lymphatic; skin; and...

  9. 36 CFR 219.36 - Definitions.

    Science.gov (United States)

    2010-07-01

    ... area: The geographic area included within the scope of a broad-scale assessment or local analysis... species diversity or their high social, cultural or economic value. Disturbance regime: Actions, functions... economic sustainability: Meeting the economic, social, aesthetic, and cultural needs and desires of...

  10. Reference: 219 [Arabidopsis Phenome Database[Archive

    Lifescience Database Archive (English)

    Full Text Available on. Phosphatidylinositol (PtdIns)(4,5)P(2) is one of the best characterized PIs; studies... homologs are found in nonplant genomes. High-performance liquid chromatography studies show that unstressed

  11. 49 CFR 219.5 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... Board (49 CFR part 1201; General Instructions 1-1). Controlled substance has the meaning assigned by 21...; (2) Impact of rail equipment with obstructions such as fallen trees, rock or snow slides, livestock... authorized to practice by the state. NTSB means the National Transportation Safety Board. Passenger...

  12. 6 CFR 21.9 - Compliance information.

    Science.gov (United States)

    2010-01-01

    ... its obligations under this part. In general, recipients should have available for the Secretary racial and ethnic data showing the extent to which members of minority groups are beneficiaries of programs... necessary to apprise such persons of the protections against discrimination assured them by the Act and...

  13. 46 CFR 10.219 - Fees.

    Science.gov (United States)

    2010-10-01

    ... rating 50 45 45 STCW certification: Original No fee No fee No fee Renewal No fee No fee No fee Reissue... address for sending payment by mail can be found at http://www.uscg.mil/stcw/ldcr-userfees.htm. (4) Checks... regarding current forms of electronic payment, go to http://www.uscg.mil/stcw/ldcr-userfees.htm. (e)...

  14. Association between ε2/3/4, Promoter Polymorphism (−491A/T, −427T/C, and −219T/G at the Apolipoprotein E Gene, and Mental Retardation in Children from an Iodine Deficiency Area, China

    Directory of Open Access Journals (Sweden)

    Jun Li

    2014-01-01

    Full Text Available Background. Several common single-nucleotide polymorphisms (SNPs at apolipoprotein E (ApoE have been linked with late onset sporadic Alzheimer’s disease and declining normative cognitive ability in elder people, but we are unclear about their relationship with cognition in children. Results. We studied -491A/T, -427T/C, and -219G/T promoter polymorphisms and ε2/ε3/ε4 at ApoE among children with mental retardation (MR, n=130, borderline MR (n=124, and controls (n=334 from an iodine deficiency area in China. The allelic and genotypic distribution of individual locus did not significantly differ among three groups with Mantel-Haenszel χ2 test (P>0.05. However, frequencies of haplotype of -491A/-427T/-219T/ε4 were distributed as MR > borderline MR > controls (P uncorrected = 0.004, indicating that the presence of this haplotype may increase the risk of disease. Conclusions. In this large population-based study in children, we did not find any significant association between single locus of the four common ApoE polymorphisms (-491A/T, -427T/C, -219T/G, and ε2/3/4 and MR or borderline MR. However, we found that the presence of ATTε4 haplotype was associated with an increased risk of MR and borderline MR. Our present work may help enlarge our knowledge of the cognitive role of ApoE across the lifespan and the mechanisms of human cognition.

  15. Final Report for grant entitled "Production of Astatine-211 for U.S. Investigators"

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, Daniel Scott

    2012-12-12

    Alpha-particle emitting radionuclides hold great promise in the therapy of cancer, but few alpha-emitters are available to investigators to evaluate. Of the alpha-emitters that have properties amenable for use in humans, 211At is of particular interest as it does not have alpha-emitting daughter radionuclides. Thus, there is a high interest in having a source of 211At for sale to investigators in the US. Production of 211At is accomplished on a cyclotron using an alpha-particle beam irradiation of bismuth metal. Unfortunately, there are few cyclotrons available that can produce an alpha particle beam for that production. The University of Washington has a cyclotron, one of three in the U.S., that is currently producing 211At. In the proposed studies, the things necessary for production and shipment of 211At to other investigators will be put into place at UW. Of major importance is the efficient production and isolation of 211At in a form that can be readily used by other investigators. In the studies, production of 211At on the UW cyclotron will be optimized by determining the best beam energy and the highest beam current to maximize 211At production. As it would be very difficult for most investigators to isolate the 211At from the irradiated target, the 211At-isolation process will be optimized and automated to more safely and efficiently obtain the 211At for shipment. Additional tasks to make the 211At available for distribution include obtaining appropriate shipping vials and containers, putting into place the requisite standard operating procedures for Radiation Safety compliance at the levels of 211At activity to be produced / shipped, and working with the Department of Energy, Isotope Development and Production for Research and Applications Program, to take orders, make shipments and be reimbursed for costs of production and shipment.

  16. Production of Astatine-211 at the Duke University Medical Center for its regional distribution

    Energy Technology Data Exchange (ETDEWEB)

    Zalutsky, Michael [Duke University Medical Center, Durham, NC (United States)

    2016-01-01

    Systemic targeted radiation therapy and radioimmunotherapy continue to be important tools in the treatment of certain cancers. Because of their high energy and short path length, alpha particle emitters such as 211At are more effective than either external beam x- ray or in vivo beta radiation in delivering potentially curative doses of radiation. The limited clinical trials that have been conducted to date have yielded encouraging responses in some patients, e.g., malignant brain tumors. In order to escalate the additional necessary research and development in radiochemistry, radiobiology and efficacy evaluation of alpha particle radiotherapeutics, it is universally agreed that access to an affordable, reliable supply of 211At is warranted. In conjunction with the Department of Energy's intent to enhance stable and radioactive isotope availability for research applications, it is the primary objective of this project to improve 211At production and purification capabilities at Duke so that this radionuclide can be supplied to researchers at other institutions throughout the US.The most widely used 211At production method involves the α,2n reaction on Bismuth using a cyclotron with beams ≤ 28 MeV. Yields can be enhanced with use of an internal target that allows for a higher alpha fluence plus efficient heat dissipation in the target. Both of these items are in place at Duke; however, in order to support production for multi-institutional use, irradiation campaigns in excess of 50 µAp and four hours duration will be needed. Further, post-irradiation processing equipment is lacking that will enable the distribution process. Financial support is sought for i) a shielded, ventilated processing/containment hood; ii) development of a post-irradiation target retrieval system; iii) fabrication of a 211At distillation and recovery module and iv) a performance review and, where needed, an enhancement of seven major subsystems that comprise the CS-30 Cyclotron. With these modifications in place, routine production of ≥200 mCi of At-211 should be readily achievable, given our methodological development of At-211 target preparation, internal target irradiation and dry distillation to recover the radionuclide.

  17. ATP结合盒转运子1R219K基因多态性与阿尔茨海默病相关性研究%Research on association between polymorphism of ATP-binding cassette transporter A1 and Alzheimer's disease

    Institute of Scientific and Technical Information of China (English)

    王娟; 陈卫蓉; 肖志杰

    2013-01-01

    Objective To assess the effect of single-nucleotide polymorphisms (SNPs) in the cholesterol-related genes ABCA1 exon R219K variation on the risk of AD and cognitive function.Methods Using case-control study,a total of sporadic 104 AD patients and 104 individuals above 60 years without cognitive impairment from a population of Chinese Han nationality in Changsha area were studied to determine the polymorphisms of ABCA1 R219K.Adopt SPSS 13.0 for statistical analysis.Results There were significant differences in the frequencies of three genotypes (RR、RK and KK) between the AD patients and controls (x2 =8.777,P =0.012).The frequency of KK genotype in AD group is obviously lower than that of controls (x2 =5.261,P =0.022).The frequency of KK+RK genotype in AD patients was 54.8%,was significantly lower than that of controls (70.2%,P =0.022).There was significantly higher levels of HDL-C,apoA-I and cognitive scores in the carriers of KK genotype and K allele (P < 0.05).There was significantly higher levels of MMSE and WMS scores in the carriers of K K genotype and K allele (P < 0.05).Further in accordance with memory types including long-term memory,short-term memory,transient memory,compared with RR genotype,the scores of short-term memory,transient memory of RK,KK and RK + KK genotypes were higher (P < 0.05),but there was no significant difference in the score of long-term memory (P > 0.05).Multifactor logistic regression analysis showed that carrying K allele was a single protective factor for AD.Conclusions The polymorphism of ABCA1R219K is associated with AD.Carrying K allele may play a positive role in serum lipids and cognition,and produce a protective effect on risk of AD.%目的 探讨胆固醇相关基因ABCA1外显子R219K遗传变异对阿尔茨海默病(AD)发病风险及认知功能的影响.方法 采用病例对照研究方法测定湖南长沙地区汉族人群104例散发性AD患者以及104名60岁以上认知功能正常者的ABCA1R219K

  18. Evaluation of Novel Wet Chemistry Separation and Purification Methods to Facilitate Automation of Astatine-­211 Isolation

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, Daniel Scott [Univ. of Washington, Seattle, WA (United States)

    2016-07-19

    This research is a collaborative effort between the research groups of the PIs, Dr. D. Scott Wilbur in the Department of Radiation Oncology at the University of Washington (UW) and Matthew O’Hara at the Pacific Northwest National Laboratory (PNNL). In this report only those studies conducted at UW and the budget information from UW will be reported. A separate progress and financial report will be provided by PNNL. This final report outlines the experiments (Tasks) conducted and results obtained at UW from July 1, 2013 thru June 30, 2016 (2-­year project with 1 year no-­cost extension). The report divides the information on the experiments and results obtained into the 5 specific objectives of the research efforts and the Tasks within those objectives. This format is used so that it is easy to see what has been accomplished in each area. A brief summary of the major findings from the studies is provided below. Summary of Major Findings from Research/Training Activities at UW: Anion and cation exchange columns did not provide adequate 211At capture and/or extraction results under conditions studied to warrant further evaluation; PEG-­Merrifield resins containing mPEG350, mPEG750, mPEG2000 and mPEG5000 were synthesized and evaluated; All of the mPEG resins with different sized mPEG moieties conjugated gave similar 211At capture (>95%) from 8M HCl solutions and release with conc. NH4OH (~50-­80%), but very low quantities were released when NaOH was used as an eluent; Capture and release of 211At when loading [211At]astatate appeared to be similar to that of [211At]astatide on PEG columns, but further studies need to be conducted to confirm that; Capture of 211At on PEG columns was lower (e.g. 80-­90%) from solutions of 8M HNO3, but higher capture rates (e.g. 99%) can be obtained when 10M HNO3 is mixed with an equal quantity of 8M HCl; Addition of reductants to the 211At solutions did not appear to change the percent capture, but may have an effect on the % extracted; There was some indication that the PEG-­Merrifield resins could be saturated (perhaps with Bi) resulting in lower capture percentages, but more studies need to be done to confirm that; A target dissolution chamber, designed and built at PNNL, works well with syringe pumps so it can be used in an automated system; Preliminary semi-­automated 211At isolation studies have been conducted with full scale target dissolution and 211At isolation using a PEG column on the Hamilton automated system gave low overall recoveries, but HNO3 was used (rather than HCl) for loading the 211At and flow rates were not optimized; Results obtained using PEG columns are high enough to warrant further development on a fully automated system; Results obtained also indicate that additional studies are warranted to evaluate other types of columns for 211At separation from bismuth, which allow use of HNO3/HCl mixtures for loading and NaOH for eluting 211At. Such a column could greatly simplify the overall isolation process and make it easier to automate.

  19. 48 CFR 52.219-22 - Small Disadvantaged Business Status.

    Science.gov (United States)

    2010-10-01

    ... Joint Ventures. The offeror represents, as part of its offer, that it is a joint venture that complies... Business Administration or a Private Certifier in accordance with 13 CFR part 124, subpart B. For joint... in the joint venture....

  20. 48 CFR 1052.219-71 - Subcontracting Plan.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Subcontracting Plan. 1052... Subcontracting Plan. As prescribed in DTAR 1019.708-70(b), insert the following provision: Subcontracting Plan (MAR 2002) As part of its initial proposal, each large business offeror must submit a contracting...

  1. 12 CFR 219.21 - Authority, purpose and scope.

    Science.gov (United States)

    2010-01-01

    ... amended by the Annunzio-Wylie Anti-Money Laundering Act of 1992 (Pub. L. 102-550, Title XV; 106 Stat. 3672... recordkeeping and reporting requirements will assist in the prosecution of money laundering activities and...

  2. 48 CFR 219.7103-2 - Contracting officer responsibilities.

    Science.gov (United States)

    2010-10-01

    ... REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Pilot Mentor-Protege... the clause at 252.232-7005, Reimbursement of Subcontractor Advance Payments—DoD Pilot Mentor-Protege Program, when a mentor firm provides advance payments to a protege firm under the Program and the...

  3. 48 CFR 1552.219-70 - Mentor-Protege Program.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Mentor-Protege Program... Mentor-Protege Program. As prescribed in 1519.203(a), insert the following clause: Mentor-Protege Program OCT 2000 (a) The Contractor has been approved to participate in the EPA Mentor-Protege program....

  4. 34 CFR 685.219 - Public Service Loan Forgiveness Program.

    Science.gov (United States)

    2010-07-01

    ... organization that is publicly funded and whose principal activities pertain to crime prevention, control or reduction of crime, or the enforcement of criminal law. Military service, for uniformed members of the U.S... are defined by the Bureau of Labor Statistics), public education, public library services,...

  5. Dicty_cDB: VFB219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ( AY785660 |pid:none) Trypanosoma cruzi strain Dm 28 c c... 405 e-111 AY785657_1( AY785657 |pid:none) Trypanosoma cruzi strain Colomb...ian... 405 e-111 protein update 2009. 6.17 PSORT psg: 0.

  6. 49 CFR 219.903 - Retention of drug testing records.

    Science.gov (United States)

    2010-10-01

    .... (4) Records related to employee training: (i) Materials on drug abuse awareness, including a copy of... the following records for a minimum of five years: (i) A summary record of each covered employee's... verifying the existence of a medical explanation of the inability of a covered employee to provide...

  7. 30 CFR 219.410 - What does this subpart contain?

    Science.gov (United States)

    2010-07-01

    ..., Louisiana, Mississippi, and Texas (collectively identified as the Gulf producing States); to eligible coastal political subdivisions within those States; and to the Land and Water Conservation Fund. Shared... coastal protection, including conservation, coastal restoration, hurricane protection, and...

  8. Dicty_cDB: SSD219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available LYLYYT SGEKKDIPFVPKFAPAFNPKTAGSHSGTKGAKGVVKSKHG*ik*******ii*yits*st fqsysnsthyhyhhiqnlkpkkkkkkkkkkklynnc--- ...YLYYT SGEKKDIPFVPKFAPAFNPKTAGSHSGTKGAKGVVKSKHG*ik*******ii*yits*st fqsysnsthyhyhhiqnlkpkkkkkkkkkkklynn

  9. Dicty_cDB: VFA219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available N BD092935 |BD092935.1 Methods and compositions for synthesis of long chain poly...unsaturated fatty acids in plants. 1213 0.0 3 BD082645 |BD082645.1 Methods and compositions for synthesis of... long chain polyunsaturated fatty acids. 1213 0.0 3 BD082630 |BD082630.1 Methods and compositions for synthe

  10. Dicty_cDB: SFD219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 90353.1 sae68c10.y1 Gm-c1064 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1064-3212 5' similar to TR:...049 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1049-1199 5' similar to T...c1007 Glycine max cDNA clone GENOME SYSTEMS CLONE ID: Gm-c1007-2626 5' similar to TR:O65744 O65744 GDP DISSO...TION INHIBITOR. ;, mRNA sequence. 62 4e-08 2 BI315670 |BI315670.1 saf75f12.y1 Gm-c1078 Glycine max cDNA clone GENOME SYSTEMS...sequence. 62 1e-07 2 AI437629 |AI437629.1 sa37e09.y1 Gm-c1004 Glycine max cDNA clone GENOME SYSTEMS

  11. 48 CFR 52.219-1 - Small Business Program Representations.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 2 2010-10-01 2010-10-01 false Small Business Program... Classification System (NAICS) code for this acquisition is— . (2) The small business size standard is... Small Business Administration, and no material change in ownership and control, principal office,...

  12. 47 CFR 90.219 - Use of signal boosters.

    Science.gov (United States)

    2010-10-01

    ... to operate radio systems in the frequency bands above 150 MHz may employ signal boosters at fixed... fill in only weak signal areas and cannot extend the system's normal signal coverage area. (b) Class A... effective radiated power (ERP) of the unit to a maximum of 5 watts under all conditions. Class B...

  13. 48 CFR 52.219-2 - Equal Low Bids.

    Science.gov (United States)

    2010-10-01

    ...) This provision applies to small business concerns only. (b) The bidder's status as a labor surplus area...) amount to more than 50 percent of the contract price. (c) Failure to identify the labor surplus areas...

  14. 48 CFR 219.806 - Pricing the 8(a) contract.

    Science.gov (United States)

    2010-10-01

    ..., DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Contracting With the Small Business... officer shall notify the SBA prior to withdrawing a requirement from the 8(a) Program due to failure...

  15. Dicty_cDB: VSF219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available lated Amino Acid sequence (All Frames) Frame A: qchhlkpspentpsistrdstelpsriepqkls... pryqerstqspchplkkekrr*krn*kiihccfishrqelqrspnqksc*QLNGLIKINF LIYFKKK--- ---sqchhlkpspentpsistrdstelpsriepqk

  16. 36 CFR 219.18 - Role of advisory committees.

    Science.gov (United States)

    2010-07-01

    ... PLANNING National Forest System Land and Resource Management Planning Collaborative Planning for... variety of public purposes, particularly those groups organized to develop landscape goals (§...

  17. 49 CFR 219.203 - Responsibilities of railroads and employees.

    Science.gov (United States)

    2010-10-01

    ... involved in the accident or incident. In any case where an operator, dispatcher, signal maintainer or other... duty tour. An employee who has been transported to receive medical care is not released from duty...

  18. 36 CFR 219.17 - Interaction with private landowners.

    Science.gov (United States)

    2010-07-01

    ... AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Collaborative Planning for... activities; (c) Potential conditions and activities on the adjacent lands that may affect management...

  19. 36 CFR 219.13 - Coordination among Federal agencies.

    Science.gov (United States)

    2010-07-01

    ... AGRICULTURE PLANNING National Forest System Land and Resource Management Planning Collaborative Planning for... proposed actions; (b) For the streamlined coordination of Federal agency policies, resource management... management plans....

  20. 36 CFR 219.24 - Science consistency evaluations.

    Science.gov (United States)

    2010-07-01

    ... AGRICULTURE PLANNING National Forest System Land and Resource Management Planning The Contribution of Science... available science. (b) The science advisory board is responsible for organizing and conducting a...

  1. 49 CFR 219.405 - Co-worker report policy.

    Science.gov (United States)

    2010-10-01

    ... dependence on alcohol or a drug or by another identifiable and treatable mental or physical disorder involving the abuse of alcohol or drugs as a primary manifestation, the following conditions and procedures... that affords more favorable conditions to employees troubled by alcohol or drug abuse...

  2. 36 CFR 219.4 - Identification and consideration of issues.

    Science.gov (United States)

    2010-07-01

    ... determination, the responsible official should consider: (i) The scope, complexity, and geographic scale of... or maintenance of ecological sustainability, including maintenance or restoration of watershed function, such as water flow regimes to benefit aquatic resources, groundwater recharge, municipal...

  3. Dicty_cDB: SHH219 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available cleotide Sequence of the Haemophilus influenzae Rd Genome,Fragments Thereof, and Uses Thereof. 44 9e-05 2 U3.... 44 1e-04 2 BD425742 |BD425742.1 The Nucleotide Sequence of the Haemophilus influenzae Rd Genome,Fragments Thereof, and Uses

  4. Astatine-211 conjugated to an anti-CD20 monoclonal antibody eradicates disseminated B-cell lymphoma in a mouse model

    Energy Technology Data Exchange (ETDEWEB)

    Green, Damian J.; Shadman, Mazyar; Jones, Jon C.; Frayo, Shani; Kenoyer, Aimee L.; Hylarides, Mark; Hamlin, Donald K.; Wilbur, D. Scott; Balkan, Ethan R.; Lin, Yukang; Miller, Brian W.; Frost, Sophia; Gopal, Ajay K.; Orozco, Johnnie J.; Gooley, Ted; Laird, Kelley L.; Till, B. G.; Back, Tom; Sandmaier, B. M.; Pagel, John M.; Press, Oliver W.

    2015-03-26

    Alpha emitting radionuclides release a large amount of energy within a few cell diameters and may be particularly effective for radioimmunotherapy targeting minimal residual disease (MRD) conditions in which micrometastatic disease satellites are broadly distributed. To evaluate this hypothesis, 211At conjugated 1F5 mAb (anti-CD20) was studied in both bulky lymphoma tumor xenograft and MRD animal models. Superior treatment responses to 211At conjugated 1F5 mAb were evident in the MRD setting. Lymphoma xenograft tumor bearing animals treated with doses of up to 48µCi of anti-CD20 211At-decaborate [211At-B10-1F5] experienced modest responses (0% cures but 2-3-fold prolongation of survival compared to negative controls). In contrast, 70% of animals in the MRD lymphoma model demonstrated complete eradication of disease when treated with 211At-B10-1F5 at a radiation dose that was less than one-third (15 µCi) of the highest dose given to xenograft animals. Tumor progression among untreated control animals in both models was uniformly lethal. After 130 days, no significant renal or hepatic toxicity is observed in the cured animals receiving 15 µCi of 211At-B10-1F5. These findings suggest that in a MRD lymphoma model, where isolated cells and tumor microclusters prevail, α-emitters may be uniquely efficacious.

  5. 20 CFR 219.34 - When evidence that a marriage has ended is required.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false When evidence that a marriage has ended is... a marriage has ended is required. Evidence of how a previous marriage ended may be required to determine whether a later marriage is valid. If a widow or widower remarried after the employee's death...

  6. 2-[1-(9-Anthrylmethyl-1H-pyrazol-3-yl]pyridine

    Directory of Open Access Journals (Sweden)

    Shi-Lu Zhang

    2009-11-01

    Full Text Available The title compound, C23H17N3, can be used in coordination chemistry. The anthracene ring makes dihedral angles of 86.08 (5 and 76.63 (6°, respectively, with the pyridine and pyrazole rings. The dihedral angle between the pyrazole and pyrimidine rings is 11.79 (7°. In the structure, weak intermolecular C—H...N hydrogen bonds are observed.

  7. Codon 219 polymorphism of PRNP in healthy caucasians and Creutzfeldt-Jakob disease patients

    Energy Technology Data Exchange (ETDEWEB)

    Petraroli, R.; Pocchiari, M. [Instituto Superiore di Sanita, Rome (Italy)

    1996-04-01

    A number of point and insert mutations of the PrP gene (PRNP) have been linked to familial Creutzfeldt-Jakob disease (CJD) and Gerstmann-Straussler-Scheinker disease (GSS). Moreover, the methionine/valine homozygosity at the polymorphic codon 129 of PRNP may cause a predisposition to sporadic and iatrogenic CJD or may control the age at onset of familial cases carrying either the 144-bp insertion or codon 178, codon 198, and codon 210 pathogenic mutations in PRNP. In addition, the association of methionine or valine at codon 129 and the point mutation at codon 178 on the same allele seem to play an important role in determining either fatal familial insomnia or CJD. However, it is noteworthy that a relationship between codon 129 polymorphism and accelerated pathogenesis (early age at onset or shorter duration of the disease) has not been seen in familial CJD patients with codon 200 mutation or in GSS patients with codon 102 mutation, arguing that other, as yet unidentified, gene products or environmental factors, or both, may influence the clinical expression of these diseases. 17 refs.

  8. 20 CFR 219.21 - Types of evidence to prove age.

    Science.gov (United States)

    2010-04-01

    ...) Selective service registration record. (9) Census record. (10) School record. (11) Vaccination record. (12... registration of birth made before age 5. (b) Other evidence of age. If an individual cannot obtain...

  9. 7 CFR 2.19 - Under Secretary for Food, Nutrition, and Consumer Services.

    Science.gov (United States)

    2010-01-01

    ..., Extension, and Teaching Policy Act of 1977 (7 U.S.C. 3318). (4) Related to committee management. Establish... information. (i) Develop techniques and equipment to assist consumers in the home and in institutions in.... (iii) Develop suitable and safe preparation and management procedures to retain nutritional and...

  10. 48 CFR 252.219-7003 - Small business subcontracting plan (DoD contracts).

    Science.gov (United States)

    2010-10-01

    ... subcontracting goal. (e) A mentor firm, under the Pilot Mentor-Protege Program established under Section 831 of... awarded— (1) Protege firms which are qualified organizations employing the severely handicapped; and (2) Former protege firms that meet the criteria in Section 831(g)(4) of Pub. L. 101-510. (f) The master...

  11. 48 CFR 952.219-70 - DOE Mentor-Protege program.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false DOE Mentor-Protege program...-Protege program. In accordance with 919.7014 insert the following provision in applicable solicitations. DOE Mentor-Protege Program (MAY 2000) The Department of Energy has established a...

  12. 48 CFR 52.219-18 - Notification of Competition Limited to Eligible 8(a) Concerns.

    Science.gov (United States)

    2010-10-01

    ... the acquisition is for a product in a class for which the Small Business Administration has determined... Eligible 8(a) Concerns (JUN 2003) (a) Offers are solicited only from small business concerns expressly certified by the Small Business Administration (SBA) for participation in the SBA's 8(a) Program and...

  13. 32 CFR 219.101 - To what does this policy apply?

    Science.gov (United States)

    2010-07-01

    ..., such as (i) research on regular and special education instructional strategies, or (ii) research on the effectiveness of or the comparison among instructional techniques, curricula, or classroom management...

  14. SUBTASK 2.19 – OPERATIONAL FLEXIBILITY OF CO2 TRANSPORT AND STORAGE

    Energy Technology Data Exchange (ETDEWEB)

    Jensen, Melanie; Schlasner, Steven; Sorensen, James; Hamling, John

    2014-12-31

    Carbon dioxide (CO2) is produced in large quantities during electricity generation and by industrial processes. These CO2 streams vary in terms of both composition and mass flow rate, sometimes substantially. The impact of a varying CO2 stream on pipeline and storage operation is not fully understood in terms of either operability or infrastructure robustness. This study was performed to summarize basic background from the literature on the topic of operational flexibility of CO2 transport and storage, but the primary focus was on compiling real-world lessons learned about flexible operation of CO2 pipelines and storage from both large-scale field demonstrations and commercial operating experience. Modeling and pilot-scale results of research in this area were included to illustrate some of the questions that exist relative to operation of carbon capture and storage (CCS) projects with variable CO2 streams. It is hoped that this report’s real-world findings provide readers with useful information on the topic of transport and storage of variable CO2 streams. The real-world results were obtained from two sources. The first source consisted of five full-scale, commercial transport–storage projects: Sleipner, Snøhvit, In Salah, Weyburn, and Illinois Basin–Decatur. These scenarios were reviewed to determine the information that is available about CO2 stream variability/intermittency on these demonstration-scale projects. The five projects all experienced mass flow variability or an interruption in flow. In each case, pipeline and/or injection engineers were able to accommodate any issues that arose. Significant variability in composition has not been an issue at these five sites. The second source of real- world results was telephone interviews conducted with experts in CO2 pipeline transport, injection, and storage during which commercial anecdotal information was acquired to augment that found during the literature search of the five full-scale projects. The experts represented a range of disciplines and hailed from North America and Europe. Major findings of the study are that compression and transport of CO2 for enhanced oil recovery (EOR) purposes in the United States has shown that impurities are not likely to cause transport problems if CO2 stream composition standards are maintained and pressures are kept at 10.3 MPa or higher. Cyclic, or otherwise intermittent, CO2 supplies historically have not impacted in-field distribution pipeline networks, wellbore integrity, or reservoir conditions. The U.S. EOR industry has demonstrated that it is possible to adapt to variability and intermittency in CO2 supply through flexible operation of the pipeline and geologic storage facility. This CO2 transport and injection experience represents knowledge that can be applied in future CCS projects. A number of gaps in knowledge were identified that may benefit from future research and development, further enhancing the possibility for widespread application of CCS. This project was funded through the Energy & Environmental Research Center–U.S. Department of Energy Joint Program on Research and Development for Fossil Energy-Related Resources Cooperative Agreement No. DE-FC26-08NT43291. Nonfederal funding was provided by the IEA Greenhouse Gas R&D Programme.

  15. 36 CFR 219.11 - Monitoring and evaluation for adaptive management.

    Science.gov (United States)

    2010-07-01

    ... expectation that anticipated funding is adequate to complete any required monitoring and evaluation prior to..., state, local, and tribal governments, scientific and academic communities, and others. In addition, the... from previous years. The summary must include: (i) A description of the progress toward achievement...

  16. 48 CFR 1052.219-70 - SF 294 and SF 295 Reporting.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false SF 294 and SF 295... SF 294 and SF 295 Reporting. Per DTAR 1019.708-70(a), insert the following clause: SF 294 and SF 295... Small Business Subcontracting Plan” in Section I and the contract schedule, SF 294 and SF 295...

  17. Calibration of ground-based lidar instrument WLS7-219

    DEFF Research Database (Denmark)

    Gómez Arranz, Paula; Wagner, Rozenn

    This report presents the result of the lidar calibration performed for the given WLS7 Windcube at DTU’s test site for large wind turbine at Høvsøre, Denmark. Calibration is here understood as the establishment of a relation between the reference wind speed measurements with measurement uncertaint......This report presents the result of the lidar calibration performed for the given WLS7 Windcube at DTU’s test site for large wind turbine at Høvsøre, Denmark. Calibration is here understood as the establishment of a relation between the reference wind speed measurements with measurement...... uncertainties provided by measurement standard and corresponding lidar wind speed indications with associated measurement uncertainties. The lidar calibration concerns the 10 minute mean wind speed measurements. The comparison of the lidar measurements of the wind direction with that from wind vanes...

  18. 29 CFR 778.219 - Pay for foregoing holidays and vacations.

    Science.gov (United States)

    2010-07-01

    ... he is owed an additional $25 as overtime premium (additional half-time) for the 10 hours in excess of... sum as vacation pay. This is a matter of private contract between the parties who may agree that... additional $25 as overtime premium (additional half-time) for the 10 hours in excess of 40. His regular...

  19. 49 CFR 219.201 - Events for which testing is required.

    Science.gov (United States)

    2010-10-01

    ... representative exercises good faith judgement in making the required determinations. (ii) The railroad... made, and the person making the decision. (iv) Any estimates of railroad property damage made by... not) in making the decision whether testing is required, subject to the same requirement that...

  20. 48 CFR 1852.219-84 - Limitation of the principal investigator-STTR program.

    Science.gov (United States)

    2010-10-01

    ... clause is with the small business concern (SBC)/Contractor or the research institution (RI). Primary... SBC/Contractor or RI. (b) The PI is considered to be key personnel in the performance of this contract. The SBC/Contractor, whether or not the employer of the PI, shall exercise primary management...

  1. 48 CFR 52.219-16 - Liquidated Damages-Subcontracting Plan.

    Science.gov (United States)

    2010-10-01

    ... clause in this contract entitled “Small Business Subcontracting Plan,” or willful or intentional action... contract entitled “Small Business Subcontracting Plan,” the Contractor shall pay the Government liquidated... following clause: Liquidated Damages—Subcontracting Plan (JAN 1999) (a) Failure to make a good faith...

  2. 48 CFR 219.202-5 - Data collection and reporting requirements.

    Science.gov (United States)

    2010-10-01

    ... ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF DEFENSE SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies... price by the low responsive offer. (3) For partial small business set-asides with preferential... departments and agencies. Reports must include— (i) Justification for failure to meet goals established by...

  3. 48 CFR 3052.219-71 - DHS mentor-protégé program.

    Science.gov (United States)

    2010-10-01

    ..., which are small businesses, veteran-owned small businesses, service-disabled veteran-owned small businesses, HUBZone small businesses, small disadvantaged businesses, and women-owned small business concerns... providing developmental assistance to eligible small business protégé entities......

  4. 48 CFR 1552.219-71 - Procedures for Participation in the EPA Mentor-Protege Program.

    Science.gov (United States)

    2010-10-01

    ... Procurement Operations Division (CPOD-Norwood), U.S. Environmental Protection Agency, 26 West Martin Luther King Drive, Cincinnati, OH 45268, Telephone: (513) 487-2024 Fax: (513) 487-2004. (End of provision) ... officer after the SBA has completed any formal determinations. (e) The offeror shall submit an...

  5. Morphological and biochemical responses of Oryza sativa L. (cultivar MR219) to ion beam irradiation

    Institute of Scientific and Technical Information of China (English)

    Anna Pick Kiong LING; Ying Chian UNG; Sobri HUSSEIN; Abdul Rahim HARUN; Atsushi TANAKA; Hase YOSHIHIRO

    2013-01-01

    Objective:Heavy ion beam, which has emerged as a new mutagen in the mutation breeding of crops and ornamental plants, is expected to result in the induction of novel mutations. This study investigates the morphological and biochemical responses of Oryza sativa toward different doses of carbon ion beam irradiation. Methods: In this study, the dry seeds of O. sativa were irradiated at 0, 20, 40, 60, 80, 100, and 120 Gy, fol owed by in-vitro germination under control ed conditions. Morphological and biochemical studies were conducted to investigate the morphological and physiological responses of O. sativa towards ion beam irradiation. Results: The study demonstrated that low doses (10 Gy) of ion beam have a stimulating effect on the height, root length, and fresh weight of the plantlets but not on the number of leaves. Meanwhile, doses higher than 10 Gy caused reductions in all the morphological parameters studied as compared to the control samples. The highest total soluble protein content [(2.11±0.47) mg/g FW] was observed in plantlets irradiated at 20 Gy. All irradiated plantlets were found to have 0.85%to 58.32%higher specific activity of peroxidase as compared to the control samples. The present study also revealed that low doses of ion beam (10 and 20 Gy) had negligible effect on the total chlorophyl content of O. sativa plantlets while 40 Gy had a stimulating effect on the chlorophyll content. Plantlets irradiated between 40 to 120 Gy were shown to be 0.38%to 9.98%higher in total soluble nitrogen content which, however, was not significantly different from the control samples. Conclusions:Carbon ion beam irradiation administered at low to moderate doses of 10 to 40 Gy may induce O. sativa mutants with superior characteristics.

  6. Morphological and biochemical responses of Oryza sativa L. (cultivar MR219) to ion beam irradiation*

    Science.gov (United States)

    Ling, Anna Pick Kiong; Ung, Ying Chian; Hussein, Sobri; Harun, Abdul Rahim; Tanaka, Atsushi; Yoshihiro, Hase

    2013-01-01

    Objective: Heavy ion beam, which has emerged as a new mutagen in the mutation breeding of crops and ornamental plants, is expected to result in the induction of novel mutations. This study investigates the morphological and biochemical responses of Oryza sativa toward different doses of carbon ion beam irradiation. Methods: In this study, the dry seeds of O. sativa were irradiated at 0, 20, 40, 60, 80, 100, and 120 Gy, followed by in-vitro germination under controlled conditions. Morphological and biochemical studies were conducted to investigate the morphological and physiological responses of O. sativa towards ion beam irradiation. Results: The study demonstrated that low doses (10 Gy) of ion beam have a stimulating effect on the height, root length, and fresh weight of the plantlets but not on the number of leaves. Meanwhile, doses higher than 10 Gy caused reductions in all the morphological parameters studied as compared to the control samples. The highest total soluble protein content [(2.11±0.47) mg/g FW] was observed in plantlets irradiated at 20 Gy. All irradiated plantlets were found to have 0.85% to 58.32% higher specific activity of peroxidase as compared to the control samples. The present study also revealed that low doses of ion beam (10 and 20 Gy) had negligible effect on the total chlorophyll content of O. sativa plantlets while 40 Gy had a stimulating effect on the chlorophyll content. Plantlets irradiated between 40 to 120 Gy were shown to be 0.38% to 9.98% higher in total soluble nitrogen content which, however, was not significantly different from the control samples. Conclusions: Carbon ion beam irradiation administered at low to moderate doses of 10 to 40 Gy may induce O. sativa mutants with superior characteristics. PMID:24302713

  7. Calibration of ground-based Lidar instrument WLS7-219

    DEFF Research Database (Denmark)

    Yordanova, Ginka; Gómez Arranz, Paula

    This report presents the result of the lidar calibration performed for the given WLS7 Windcube at DTU’s test site for large wind turbines at Høvsøre, Denmark. Calibration is here understood as the establishment of a relation between the reference wind speed measurements with measurement uncertain......This report presents the result of the lidar calibration performed for the given WLS7 Windcube at DTU’s test site for large wind turbines at Høvsøre, Denmark. Calibration is here understood as the establishment of a relation between the reference wind speed measurements with measurement...... uncertainties provided by measurement standard and corresponding lidar wind speed indications with associated measurement uncertainties. The lidar calibration concerns the 10 minute mean wind speed measurements. The comparison of the lidar measurements of the wind direction with that from wind vanes...

  8. 28 CFR 2.219 - Maximum terms of imprisonment and supervised release.

    Science.gov (United States)

    2010-07-01

    ..., SUPERVISION AND RECOMMITMENT OF PRISONERS, YOUTH OFFENDERS, AND JUVENILE DELINQUENTS District of Columbia... supervised release that the sentencing court was authorized to impose for the offense of conviction, less the... from the sentencing judge certifying that the defendant is a sex offender. (3) If the...

  9. Yeast Interacting Proteins Database: YPL031C, YPL219W [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available ting the cellular response to nutrient levels and environmental conditions and progression through the cell ...e cellular response to nutrient levels and environmental conditions and progression through the cell cycle R

  10. 10 CFR Appendix C to Part 20 - Quantities 1 of Licensed Material Requiring Labeling

    Science.gov (United States)

    2010-01-01

    ... Polonium-205 1,000 Polonium-207 1,000 Polonium-210 0.1 Astatine-207 100 Astatine-211 10 Radon-220 1 Radon-222 1 Francium-222 100 Francium-223 100 Radium-223 0.1 Radium-224 0.1 Radium-225 0.1 Radium-226...

  11. ПC-219车辆轮对轴承圈过盈量检测仪%Interference tester for the bearing rings on wheelsets of ПC - 219 railcars

    Institute of Scientific and Technical Information of China (English)

    胥金荣

    2006-01-01

      与铁路行车安全紧密相关的问题之一,就是缺少用于批量检测轴承内圈在轮对车轴上套装可靠过盈量的仪器.目前所使用的常规方法,其可靠性较低.因为它是以套装之前测量轴承圈和轮对车轴的直径为依据的,并没有考虑到轴承圈的加热和与车轴的机械连接,这些随机工艺过程中的许多因素对套装质量将产生较大的影响.

  12. La Desercion Escolar en los Niveles de Sexto y Noveno Grado: Una Comparacion Entre Zonas Rurales y Urbanas. Boletin 219 (The Educational Desertion in the 6th and 9th Grades: A Comparison Between Rural and Urban Zones. Bulletin 219).

    Science.gov (United States)

    Lopez, Maria I. Hernandez; And Others

    In 1962 and again in 1965, a group of sixth and ninth grade students in selected schools in four Puerto Rican communities were interviewed to investigate the factors influencing students' decision to withdraw from school before completing twelfth grade and to identify some characteristics of dropouts. Of 616 students interviewed in 1962, 20.9% of…

  13. 75 FR 25844 - Class Deviation From FAR 52.219-7, Notice of Partial Small Business Set-Aside

    Science.gov (United States)

    2010-05-10

    ... portion at a price higher than its offer price under the non-set-aside portion. The proposed revisions are... DOCUMENT. I237.06 NOTICE OF PARTIAL SMALL BUSINESS SET-ASIDE (DEVIATION) (DESC) (a) DEFINITION. Small... negotiated as to price and an evaluation will be made as though there were no set-aside. (4) For the...

  14. Crystallization and preliminary crystallographic analysis of the catechol 2,3-dioxygenase PheB from Bacillus stearothermophilus BR219

    Energy Technology Data Exchange (ETDEWEB)

    Sugimoto, Keisuke; Matsufuzi, Kazuki; Ohnuma, Hiroaki [Department of Material Chemistry, Asahikawa National College of Technology, 2-2-1-6 Shunko-dai, Asahikawa, Hokkaido 071-8142 (Japan); Senda, Miki [Japan Biological Information Research Center (JBIRC), Japan Biological Informatics Consortium (JBIC), 2-42 Aomi, Koto-ku, Tokyo 135-0064 (Japan); Fukuda, Masao [Department of Bioengineering, Nagaoka University of Technology, Nagaoka, Niigata 940-2188 (Japan); Senda, Toshiya, E-mail: tsenda@jbirc.aist.go.jp [Biological Information Research Center (BIRC), National Institute of Advanced Industrial Science and Technology (AIST), 2-42 Aomi, Koto-ku, Tokyo (Japan); Department of Material Chemistry, Asahikawa National College of Technology, 2-2-1-6 Shunko-dai, Asahikawa, Hokkaido 071-8142 (Japan)

    2006-02-01

    PheB, an extradiol-cleaving catecholic dioxygenase, was crystallized by the hanging-drop vapour-diffusion method using PEG 4000 as a precipitant. The crystal belongs to the orthorhombic system, space group P2{sub 1}2{sub 1}2{sub 1}, and diffracts to 2.3 Å resolution. Class II extradiol-cleaving catecholic dioxygenase, a key enzyme of aromatic compound degradation in bacteria, cleaves the aromatic ring of catechol by adding two O atoms. PheB is one of the class II extradiol-cleaving catecholic dioxygenases and shows a high substrate specificity for catechol derivatives, which have one aromatic ring. In order to reveal the mechanism of the substrate specificity of PheB, PheB has been crystallized by the hanging-drop vapour-diffusion method using PEG 4000 as a precipitant. The space group of the obtained crystal was P2{sub 1}2{sub 1}2{sub 1}, with unit-cell parameters a = 65.5, b = 119.2, c = 158.7 Å. The crystal diffracted to 2.3 Å resolution.

  15. Jürgen Jaspers: De klank van de stad. Stedelijke meertaligheid en interculturele communicatie (red.). Leuven, ACCO, 2009. 219 blz.

    NARCIS (Netherlands)

    Nortier, J.M.

    2010-01-01

    De klank van de stad is geschreven naar aanleiding van een congres over hetzelfde thema, stedelijke meertaligheid (maart 2008, Antwerpen). De auteurs waren in meerderheid sprekers bij het congres die hun presentaties in soms wat gewijzigde vorm hebben opgeschreven. Iedereen die wel eens te maken hee

  16. 48 CFR 852.219-11 - VA notice of total veteran-owned small business set-aside.

    Science.gov (United States)

    2010-10-01

    ...) A joint venture may be considered a veteran-owned small business concern if: (1) At least one member of the joint venture is a veteran-owned small business concern, and makes the following... corresponding to the NAICS code assigned to the procurement; (3) The joint venture meets the requirements...

  17. Lithium-vanadium advanced blanket development. ITER final report on U.S. contribution: Task T219/T220

    Energy Technology Data Exchange (ETDEWEB)

    Smith, D.L.; Mattas, R.F. [comps.

    1997-07-01

    The objective of this task is to develop the required data base and demonstrate the performance of a liquid lithium-vanadium advanced blanket design. The task has two main activities related to vanadium structural material and liquid lithium system developments. The vanadium alloy development activity included four subtasks: (1.1) baseline mechanical properties of non irradiated base metal and weld metal joints; (1.2) compatibility with liquid lithium; (1.3) material irradiation tests; and (1.4) development of material manufacturing and joining methods. The lithium blanket technology activity included four subtasks: (2.1) electrical insulation development and testing for liquid metal systems; (2.2) MHD pressure drop and heat transfer study for self-cooled liquid metal systems; (2.3) chemistry of liquid lithium; and (2.4) design, fabrication and testing of ITER relevant size blanket mockups. A summary of the progress and results obtained during the period 1995 and 1996 in each of the subtask areas is presented in this report.

  18. 50 CFR 226.219 - Critical habitat for the Southern Distinct Population Segment of North American Green Sturgeon...

    Science.gov (United States)

    2010-10-01

    ....); Stuart Slough (46°41′9″ N./123°52′16″ W.); Willapa River (46°38′50″ N./123°38′50″ W.). (ix) Grays Harbor, Washington. All tidally influenced areas of Grays Harbor up to the elevation of mean higher high water... Fuca, Washington. The Strait of Juan de Fuca includes all U.S. marine waters: in Clallam County east...

  19. 75 FR 53533 - Procedures for the Handling of Retaliation Complaints Under Section 219 of the Consumer Product...

    Science.gov (United States)

    2010-08-31

    ... otherwise, or for the personal use, consumption or enjoyment of a consumer in or around a permanent or...: (i) Any article which is not customarily produced or distributed for sale to, or use or consumption by, or enjoyment of, a consumer; (ii) Tobacco and tobacco products; (iii) Motor vehicles or...

  20. 30 CFR 219.416 - How will the qualified OCS revenues be allocated to coastal political subdivisions within the...

    Science.gov (United States)

    2010-07-01

    ... political subdivisions in the proportion that each coastal political subdivision's miles of coastline bears to the number of miles of coastline of all coastal political subdivisions in the producing State. Except that, for the State of Louisiana, proxy coastline lengths for coastal political...

  1. 30 CFR 219.417 - How will MMS disburse qualified OCS revenues to the coastal political subdivisions if, during any...

    Science.gov (United States)

    2010-07-01

    ... political subdivision's miles of coastline bears to the number of miles of coastline of all coastal political subdivisions in the State. Except that, for the State of Louisiana, proxy coastline lengths for coastal political subdivisions without a coastline will be considered to be 1/3 the average length of...

  2. 30 CFR 219.414 - How will MMS determine each Gulf producing State's share of the qualified OCS revenues?

    Science.gov (United States)

    2010-07-01

    ... the geographic centers of each applicable leased tract to each Gulf producing State's coastline. (b... on the State's coastline that are closest to the geographic centers of the applicable leased...

  3. 78 FR 35567 - Safety Zone; Lower Mississippi River, Mile Marker 219 to Mile Marker 229, in the Vicinity of Port...

    Science.gov (United States)

    2013-06-13

    ...: If you have questions on this rule, call or email Lieutenant Christopher Norton, Coast Guard Marine Safety Unit Baton Rouge; telephone (225) 298-5400, email Christopher.R.Norton@uscg.mil . If you have... Norton, Marine Safety Unit Baton Rouge, at (225) 298-5400 or Christopher.R.Norton@uscg.mil ....

  4. Proceedings of US/Japan workshop, Q219 on high heat flux components and plasma surface interactions for next fusion devices

    Energy Technology Data Exchange (ETDEWEB)

    Ulrickson, M.A.; Stevens, P.L.; Hino, T.; Hirohata, Y. [eds.

    1996-12-01

    This report contains the viewgraphs from the proceedings of US/Japan Workshop on High Heat Flux Components and Plasma Surface Interactions for Next Fusion Devices. Some of the general topics covered by this report are: PFC/PSI in tokamak and helical devices; development of high heat flux components; PSIS and plasma facing materials;tritium; and material damage.

  5. Improving Lowland Rice (O. sativa L. cv. MR219) Plant Growth Variables, Nutrients Uptake, and Nutrients Recovery Using Crude Humic Substances.

    Science.gov (United States)

    Palanivell, Perumal; Ahmed, Osumanu Haruna; Ab Majid, Nik Muhamad; Jalloh, Mohamadu Boyie; Susilawati, Kasim

    2015-01-01

    High cation exchange capacity and organic matter content of crude humic substances from compost could be exploited to reduce ammonia loss from urea and to as well improve rice growth and soil chemical properties for efficient nutrients utilization in lowland rice cultivation. Close-dynamic air flow system was used to determine the effects of crude humic substances on ammonia volatilization. A pot experiment was conducted to determine the effects of crude humic substances on rice plant growth, nutrients uptake, nutrients recovery, and soil chemical properties using an acid soil mixed with three rates of crude humic substances (20, 40, and 60 g pot(-1)). Standard procedures were used to evaluate rice plant dry matter production, nutrients uptake, nutrients recovery, and soil chemical properties. Application of crude humic substances increased ammonia volatilization. However, the lowest rate of crude humic substances (20 g pot(-1)) significantly improved total dry matter, nutrients uptake, nutrients recovery, and soil nutrients availability compared with crude humic substances (40 and 60 g pot(-1)) and the normal fertilization. Apart from improving growth of rice plants, crude humic substances can be used to ameliorate acid soils in rice cultivation. The findings of this study are being validated in our ongoing field trials.

  6. Improving Lowland Rice (O. sativa L. cv. MR219 Plant Growth Variables, Nutrients Uptake, and Nutrients Recovery Using Crude Humic Substances

    Directory of Open Access Journals (Sweden)

    Perumal Palanivell

    2015-01-01

    Full Text Available High cation exchange capacity and organic matter content of crude humic substances from compost could be exploited to reduce ammonia loss from urea and to as well improve rice growth and soil chemical properties for efficient nutrients utilization in lowland rice cultivation. Close-dynamic air flow system was used to determine the effects of crude humic substances on ammonia volatilization. A pot experiment was conducted to determine the effects of crude humic substances on rice plant growth, nutrients uptake, nutrients recovery, and soil chemical properties using an acid soil mixed with three rates of crude humic substances (20, 40, and 60 g pot−1. Standard procedures were used to evaluate rice plant dry matter production, nutrients uptake, nutrients recovery, and soil chemical properties. Application of crude humic substances increased ammonia volatilization. However, the lowest rate of crude humic substances (20 g pot−1 significantly improved total dry matter, nutrients uptake, nutrients recovery, and soil nutrients availability compared with crude humic substances (40 and 60 g pot−1 and the normal fertilization. Apart from improving growth of rice plants, crude humic substances can be used to ameliorate acid soils in rice cultivation. The findings of this study are being validated in our ongoing field trials.

  7. SU-E-J-219: A Dixon Based Pseudo-CT Generation Method for MR-Only Radiotherapy Treatment Planning of the Pelvis and Head and Neck

    Energy Technology Data Exchange (ETDEWEB)

    Maspero, M.; Meijer, G.J.; Lagendijk, J.J.W.; Berg, C.A.T. van den [Department of Radiotherapy, UMC Utrecht (Netherlands); Seevinck, P.R.; Viergever, M.A. [Image Science Institute, UMC Utrecht (Netherlands)

    2015-06-15

    Purpose: To develop an image processing method for MRI-based generation of electron density maps, known as pseudo-CT (pCT), without usage of model- or atlas-based segmentation, and to evaluate the method in the pelvic and head-neck region against CT. Methods: CT and MRI scans were obtained from the pelvic region of four patients in supine position using a flat table top only for CT. Stratified CT maps were generated by classifying each voxel based on HU ranges into one of four classes: air, adipose tissue, soft tissue or bone.A hierarchical region-selective algorithm, based on automatic thresholding and clustering, was used to classify tissues from MR Dixon reconstructed fat, In-Phase (IP) and Opposed-Phase (OP) images. First, a body mask was obtained by thresholding the IP image. Subsequently, an automatic threshold on the Dixon fat image differentiated soft and adipose tissue. K-means clustering on IP and OP images resulted in a mask that, via a connected neighborhood analysis, allowing the user to select the components corresponding to bone structures.The pCT was estimated through assignment of bulk HU to the tissue classes. Bone-only Digital Reconstructed Radiographs (DRR) were generated as well. The pCT images were rigidly registered to the stratified CT to allow a volumetric and voxelwise comparison. Moreover, pCTs were also calculated within the head-neck region in two volunteers using the same pipeline. Results: The volumetric comparison resulted in differences <1% for each tissue class. A voxelwise comparison showed a good classification, ranging from 64% to 98%. The primary misclassified classes were adipose/soft tissue and bone/soft tissue. As the patients have been imaged on different table tops, part of the misclassification error can be explained by misregistration. Conclusion: The proposed approach does not rely on an anatomy model providing the flexibility to successfully generate the pCT in two different body sites. This research is founded by ZonMw IMDI Programme, project name: “RASOR sharp: MRI based radiotherapy planning using a single MRI sequence”, project number: 10-104003010.

  8. Reliability and measurement error of frontal and horizontal 3D spinal motion parameters in 219 patients with chronic low back pain

    DEFF Research Database (Denmark)

    Harsted, Steen; Mieritz, Rune M; Bronfort, Gert;

    2016-01-01

    mechanical LBP, classified as either Quebec Task Force group 1, 2, 3 or 4 were included, and kinematics of the lumbar spine were sampled during standardized spinal lateral flexion and rotation motion using a 6-df instrumented spatial linkage system. Test-retest reliability and measurement error were...... evaluated using intraclass correlation coefficients ICC(1,1) and Bland-Altman limits of agreement (LOAs). RESULTS: The reliability analysis based on the whole study sample showed ICC(1,1) coefficients varying between 0.68 and 0.73 for the frontal plane and 0.33 and 0.49 for the horizontal plane. Relatively...... a stable pain level between tests, and were male. ROM measurements were more reliable in patients with a BMI higher than 30, and measurements on patients with LBP and leg pain showed higher reliability and smaller measurement error in all parameters except for the jerk index. CONCLUSION: Frontal plane...

  9. 75 FR 32773 - Auction of 218-219 MHz Service and Phase II 220 MHz Service Licenses Scheduled for December 7...

    Science.gov (United States)

    2010-06-09

    ... format documents, sign language interpreters, CART, etc.) by e-mail: FCC504@fcc.gov or phone: 202-418... Commission has authorized certain site-based, low power operations on a secondary basis in the 216-220 MHz..., the service rules permit a variety of fixed, mobile, and paging services, though the opportunities...

  10. 48 CFR 852.219-10 - VA Notice of total service-disabled veteran-owned small business set-aside.

    Science.gov (United States)

    2010-10-01

    ...; and (iv) The business has been verified for ownership and control and is so listed in the Vendor... business concern under the North American Industry Classification Systems (NAICS) code assigned to the... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false VA Notice of total...

  11. Investigations of the in Planta Expression of Active Cellobiohydrolase I: Cooperative Research and Development Final Report, CRADA Number CRD-07-219

    Energy Technology Data Exchange (ETDEWEB)

    Himmel, M.

    2011-02-01

    It was the purpose of this project to determine if cellulases produced in transgenic plants could effectively be utilized in the production of ethanol and other feedstock chemicals from lignocellulosic substrates.

  12. Nelly Hanna : Making Big Money in 1600. The Life and Time of Isma'il Abu Taqiyya, Egyptian Merchant, Syracuse University Press, Syracuse, New York, 1998, 219 p.

    Directory of Open Access Journals (Sweden)

    Daniel Panzac

    2009-01-01

    Full Text Available Nelly Hanna est professeur associé à l'Université américaine du Caire et spécialiste d'Histoire de l'époque ottomane de l'Égypte. Son œuvre s'inscrit dans le courant actuel de la recherche historique qui s'efforce, avec succès, de montrer que la période ottomane (xvie-xviiie siècles n'est pas, pour l'Égypte, aussi calamiteuse et régressive que l'on aurait trop tendance à l'admettre face à la glorieuse période précédente, celle des Mamelouks qui régnèrent du milieu du xiiie à la fin du xve si...

  13. The Beaverdam Group: Archaeological Investigations at 9EB92, 9EB207, 9EB208 and 9EB219 Richard B. Russell Multiple Resource Area, Elbert County, Georgia.

    Science.gov (United States)

    1984-01-01

    36 Laboratory Methods ........... .................. ..... .. 37 -- Lithic Analysis ................................... 37...historic activity. The majority of the historic items were expended shotgun shells and discarded cans. Lithic Analysis The majority of artifacts...recovered from the Beaverdam Group sites consists of lithic material, most of which is crudely worked. Lithic analysis proceeded on the basis of two

  14. Utilização de promotores de crescimento para frangos de corte em rações fareladas e peletizadas - DOI: 10.4025/actascianimsci.v29i2.219 Utilization of growth promoter for broiler chickens in mashed and pellets diets - DOI: 10.4025/actascianimsci.v29i2.219

    Directory of Open Access Journals (Sweden)

    Mathias Djalma Appelt

    2007-11-01

    Full Text Available Avaliou-se o efeito da suplementação de dietas com diferentes promotores de crescimento sobre o desempenho e rendimento de carcaça de frangos de corte de 1 a 42 dias de idade. Foram utilizados 576 pintos da linhagem Cobb 500, machos, alojados em cama reutilizada, distribuídos em um delineamento inteiramente casualizado, em esquema fatorial 2 x 3 (forma física da ração x diferentes promotores de crescimento, totalizando 6 tratamentos, com 6 repetições e 16 aves por unidade experimental. As características de desempenho avaliadas foram ganho de peso, peso final, consumo de ração, conversão alimentar, mortalidade e o índice de eficiência produtiva. Avaliou-se também o rendimento de carcaça, bem como rendimento em cortes, coração, fígado e gordura abdominal. Os resultados obtidos demonstram não haver efeito dos tratamentos estudados sobre as características de desempenho e rendimento de carcaça.This study evaluated the supplementation effect of diets with different growth promoters on the performance and carcass yield in broilers from 1 to 42 days of age. Five hundred seventy six broilers of the Coob 500 lineage were used, all males, lodged in reused litter, allocated according to a completely randomized design in a 2 x 3 factorial scheme (physical forms of the ration x growth promoters, totalizing 6 treatments, 6 repetitions per treatment and 16 broilers per experimental unit. The performance parameters evaluated were weight gain, final weight, feed consumption, feed conversion, mortality and index productive efficiency. The carcass yield was also evaluated, as the cuts yield and percentage of abdominal fat at 42 days. The results demonstrated no effect of the treatments studied on the performance characteristics and carcass yield.

  15. Shelf-life of ɛ-lysyl-3-(trimethylstannyl)benzamide immunoconjugates, precursors for 211At labeling of antibodies

    DEFF Research Database (Denmark)

    Aneheim, Emma; Halleröd, Jenny; Albertsson, Per;

    2015-01-01

    Astatine-211 is possibly the most promising radionuclide for targeted α-particle therapy when it comes to the treatment of occult disseminated cancer. Preclinical research has proven effective, and patient studies have been initiated based on these results. However, a lack of production capacity...

  16. Successful radioimmunotherapy of established syngeneic rat colon carcinoma with 211At-mAb

    DEFF Research Database (Denmark)

    Eriksson, Sophie E; Bäck, Tom; Elgström, Erika

    2013-01-01

    Most carcinomas are prone to metastasize despite successful treatment of the primary tumor. One way to address this clinical challenge may be targeted therapy with α-emitting radionuclides such as astatine-211 (211At). Radioimmunotherapy utilizing α-particle emitting radionuclides is considered...... colon carcinoma with tumor diameters of approximately 10 mm....

  17. Petrographic atlas characterisation of aggregates regarding potential reactivity to alkalis : RILEM TC 219-ACS recommended guidance AAR-1.2, for use with the RILEM AAR-1.1 petrographic examination method

    CERN Document Server

    Ribeiro, Maria; Broekmans, Maarten; Sims, Ian

    2016-01-01

    This RILEM AAR 1.2 Atlas is complementary to the petrographic method described in RILEM AAR 1.1. It is designed and intended to assist in the identification of alkali-reactive rock types in concrete aggregate by thin-section petrography. Additional issues include: • optical thin-section petrography conforming to RILEM AAR 1.1 is considered the prime assessment method for aggregate materials, being effective regarding cost and time. Unequivocal identification of minerals in very-fine grained rock types may however require use of supplementary methods. • the atlas adheres to internationally adopted schemes for rock classification and nomenclature, as recommended in AAR 1.1. Thus, rock types are classified as igneous, sedimentary or metamorphic based upon mineral content, microstructure and texture/fabric. • in addition, the atlas identifies known alkali-reactive silica types in each rock type presented. It also identifies consistent coincidence between certain lithologies and silica types; however, it ref...

  18. Depaule Jean-Charles (avec la collaboration de Jean-Luc Arnaud, À travers le mur, Marseille, éditions Parenthèses, collection Eupalinos, 2014, 219 p.

    Directory of Open Access Journals (Sweden)

    Anna Madoeuf

    2014-09-01

    Full Text Available Saluons la réédition, aux éditions Parenthèses, dans la collection Eupalinos, d’À travers le mur, de Jean-Charles Depaule, ouvrage qui est tant une contribution rare et originale aux études urbaines, qu’un opus d’anthropologie sur l’espace habité, de même qu’une source de références multiples, notamment littéraires. « Rêver des lourdes portes, des passages en chicane et plus encore, peut-être des moucharabiehs perdus […] ». Cette sollicitation onirique et énigmatique, quatrième de couverture ...

  19. Application of solar energy to the supply of industrial process hot water: preliminary design and performance report. Volume I. Technical report. Aerotherm report TR-76-219. [For can washing at Campbell Soup Plant in Sacramento

    Energy Technology Data Exchange (ETDEWEB)

    None

    1976-10-14

    The design and performance of a solar hot water system for can washing at the Campbell Soup Plant in Sacramento, California, are presented. The collector field is located on the roof of the finished products warehouse of the Campbell Soup Sacramento plant. Water is supplied from a 3.8 cm (1/sup 1///sub 2/ in.) supply line which is located directly below an existing roof access hatch. A supply pipe will be brought up through that hatch. The water flow will then be split into two manifold lines which supply the dual rows of flat plate collectors. The preheated water from the flat plates is then passed into six sets of parallel connected concentrators. Each set consist of eight 1.83 x 3.05 m (6 x 10 foot) modules connected in series. The water from these units is gathered in a 3.8 cm (1/sup 1///sub 2/ in.) insulated pipe which transports it to the storage tank. This pipe will be attached to an existing pipe run until it reaches the can washing building. From there the pipe will follow the can washing building around to the storage tank. The storage tank is a 75,200 1 (20,000 gal) steel tank which is coated internally with a USDA approved phenolic liner. The outside of the tank is insulated. A 2.2 kw (3 hp) motor is used to pump the stored water for the tank into the can washing line. Detail drawings and descriptions of the collector field, installation, piping, controls, data acquisition equipment, and roof structure are included. Furthermore, a program schedule with equipment and manpower costs for successfully completing Phase II of this contract is included. Also included is an organization chart of the Phase II program personnel. (WHK)

  20. Hyperspectral surface materials map of quadrangles 3666 and 3766, Balkh (219), Mazar-e Sharif (220), Qarqin (213), and Hazara Toghai (214) quadrangles, Afghanistan, showing iron-bearing minerals and other materials

    Science.gov (United States)

    King, Trude V.V.; Hoefen, Todd M.; Kokaly, Raymond F.; Livo, Keith E.; Johnson, Michaela R.; Giles, Stuart A.

    2013-01-01

    This map shows the spatial distribution of selected iron-bearing minerals and other materials derived from analysis of airborne HyMap™ imaging spectrometer (hyperspectral) data of Afghanistan collected in late 2007. This map is one in a series of U.S. Geological Survey/Afghanistan Geological Survey quadrangle maps covering Afghanistan. Flown at an altitude of 50,000 feet (15,240 meters (m)), the HyMap™ imaging spectrometer measured reflected sunlight in 128 channels, covering wavelengths between 0.4 and 2.5 μm. The data were georeferenced, atmospherically corrected and converted to apparent surface reflectance, empirically adjusted using ground-based reflectance measurements, and combined into a mosaic with 23-m pixel spacing. Variations in water vapor and dust content of the atmosphere, in solar angle, and in surface elevation complicated correction; therefore, some classification differences may be present between adjacent flight lines. The reflectance spectrum of each pixel of HyMap™ imaging spectrometer data was compared to the reference materials in a spectral library of minerals, vegetation, water, and other materials. Minerals occurring abundantly at the surface and those having unique spectral features were easily detected and discriminated, while minerals having slightly different compositions but similar spectral features were less easily discriminated; thus, some map classes consist of several minerals having similar spectra, such as “Goethite and jarosite.” A designation of “Not classified” was assigned to the pixel when there was no match with reference spectra.

  1. RILEM recommendations for the prevention of damage by alkali-aggregate reactions in new concrete structures state-of-the-art report of the RILEM technical committee 219-ACS

    CERN Document Server

    Sims, Ian

    2016-01-01

    This book contains the full set of RILEM Recommendations which have been produced to enable engineers, specifiers and testing houses to design and produce concrete which will not suffer damage arising from alkali reactions in the concrete. There are five recommended test methods for aggregates (designated AAR-1 to AAR-5), and an overall recommendation which describes how these should be used to enable a comprehensive aggregate assessment (AAR-0). Additionally, there are two Recommended International Specifications for concrete (AAR-7.1 & 7.2) and a Preliminary International Specification for dams and other hydro structures (AAR-7.3), which describe how the aggregate assessment can be combined with other measures in the design of the concrete to produce a concrete with a minimised risk of developing damage from alkali-aggregate reactions.

  2. Thermosalinograph data of the Hawaii Ocean Time-series (HOT) program in the North Pacific 100 Miles North of Oahu, Hawaii for Cruises HOT219-227 during 2010 (NCEI Accession 0087988)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The HOT program makes repeated observations of the physics, biology and chemistry at a site approximately 100 km north of Oahu, Hawaii. Two stations are visited...

  3. Núñez Becerra, Fernanda, La prostitución y su represión en la Ciudad de México (siglo XIX). Prácticas y representaciones, Barcelona, Gedisa Editorial, 2002, 219 p.

    OpenAIRE

    Albornoz Vásquez, María Eugenia

    2006-01-01

    La autora, de formación antropóloga y doctorada en Historia por la Universidad de Paris VII Diderot, muestra a través de este ameno ensayo la importancia crucial de la figura de la prostituta en la conformación de los modelos de ser mujer en particular y de ser familia decente, en general, en la sociedad mexicana de la segunda mitad del siglo XIX. Con un estilo desenfadado y polemizante, no exento de ironía, de juicios subjetivos (decir “representaciones aburridas de mujeres acartonadas” para...

  4. Hyperspectral surface materials map of quadrangles 3666 and 3766, Balkh (219), Mazar-e Sharif (220), Qarqin (213), and Hazara Toghai (214) quadrangles, Afghanistan, showing carbonates, phyllosilicates, sulfates, altered minerals, and other materials

    Science.gov (United States)

    Kokaly, Raymond F.; King, Trude V.V.; Hoefen, Todd M.; Livo, Keith E.; Johnson, Michaela R.; Giles, Stuart A.

    2013-01-01

    This map shows the spatial distribution of selected carbonates, phyllosilicates, sulfates, altered minerals, and other materials derived from analysis of airborne HyMap™ imaging spectrometer (hyperspectral) data of Afghanistan collected in late 2007. The map is one in a series of U.S. Geological Survey/Afghanistan Geological Survey quadrangle maps covering Afghanistan. Flown at an altitude of 50,000 feet (15,240 meters (m)), the HyMap™ imaging spectrometer measured reflected sunlight in 128 channels, covering wavelengths between 0.4 and 2.5 μm. The data were georeferenced, atmospherically corrected and converted to apparent surface reflectance, empirically adjusted using ground-based reflectance measurements, and combined into a mosaic with 23-m pixel spacing. Variations in water vapor and dust content of the atmosphere, in solar angle, and in surface elevation complicated correction; therefore, some classification differences may be present between adjacent flight lines. The reflectance spectrum of each pixel of HyMap™ imaging spectrometer data was compared to the reference materials in a spectral library of minerals, vegetation, water, and other materials. Minerals occurring abundantly at the surface and those having unique spectral features were easily detected and discriminated, while minerals having slightly different compositions but similar spectral features were less easily discriminated; thus, some map classes consist of several minerals having similar spectra, such as “Epidote or chlorite.” A designation of “Not classified” was assigned to the pixel when there was no match with reference spectra.

  5. 19q13.11 microdeletion concomitant with ins(2;19)(p25.3;q13.1q13.4)dn in a boy: potential role of UBA2 in the associated phenotype.

    Science.gov (United States)

    Venegas-Vega, Carlos; Nieto-Martínez, Karem; Martínez-Herrera, Alejandro; Gómez-Laguna, Laura; Berumen, Jaime; Cervantes, Alicia; Kofman, Susana; Fernández-Ramírez, Fernando

    2014-01-01

    The 19q13.11 microdeletion syndrome (MIM613026) is a clinically recognisable condition in which a 324-kb minimal overlapping critical region has been recently described. However, genes not included within this region, such as WTIP and UBA2, have been proposed to contribute to the clinical characteristics observed in patients. Using cytogenetic techniques, single nucleotide polymorphism arrays, and the quantitative polymerase chain reaction, we identified a novel case with a 2.49-Mb deletion derived from a de novo chromosomal rearrangement. Based on a review of the literature, we support the notion that UBA2 haploinsufficiency could contribute to the phenotype of this rare genomic disorder. UBA2 belongs to a protein complex with sumoylation activity, and several transcription factors, hormone receptors, and signalling proteins related to brain and sexual development are regulated by this post-translational modification. Additional clinical reports and further research on UBA2 molecular function are warranted.

  6. Potential for Cell-Transplant Therapy with Human Neuronal Precursors to Treat Neuropathic Pain in Models of PNS and CNS Injury: Comparison of hNT2.17 and hNT2.19 Cell Lines

    Science.gov (United States)

    2012-01-01

    in- tractable pain in advanced rheumatoid arthritis ,” Clinical & Experimental Obstetrics & Gynecology, vol. 29, no. 3, pp. 197– 206, 2002. [118] B. C...Katz, “Neuropathic pain in patients with upper-extremity nerve injury,” Physiotherapy Canada, vol. 62, no. 3, pp. 190–201, 2010. Pain Research and

  7. $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with radioactive At beams

    CERN Multimedia

    We propose to study the $\\beta$-delayed fission, laser spectroscopy and radioactive decay of the newly available pure beams of neutron-deficient and neutron-rich astatine (Z=85) isotopes. The fission probability and the fission fragment distribution of the even-even isotopes $^{194,196}$Po following the $\\beta$-decay of the isotopes $^{194,196}$At will be studied with the Windmill setup. In-source laser spectroscopy will be performed on the entire astatine isotopic chain, using a combination of the Windmill setup, ISOLTRAP MR-ToF and ISOLDE Faraday. Radioactive decay data will be acquired at the Windmill setup throughout those studies and contribute to the global understanding of the phenomenon of shape coexistence in the neutron-deficient lead region.

  8. Sp ectroscopy of Low-lying States in Odd-Z Odd-A Nuclei Beyond Lead

    Institute of Scientific and Technical Information of China (English)

    U Jakobsson; S Juutinen; A Herzan; J Konki; M Leino; M Mallaburn; J Pakarinen; P Papadakis; J Partanen; P Rahkila; M Sandzelius; J Uusitalo; J Saren; C Scholey; J Sorri; S Stolze; K Auranen; H Badran; B Cederwall; D M Cox; T Grahn; P T Greenlees; R Julin

    2016-01-01

    Low-lying states in odd-Z odd-mass nuclei at the proton drip-line beyond lead have recently been studied through fusion-evaporation reactions using a gas-filled recoil separator. Isomeric 1/2+ and 13/2+ states have been observed in odd-mass astatine and francium nuclei. The systematic behaviour of the level energies of these states have been studied and a similarity between the 1/2+ state in astatine and francium has been found. Furthermore, the 13/2+ state has been observed in the francium nuclei with an oblate behaviour suggesting a coupling of the i13/2 proton to the 2p−2h intruder excitation.

  9. Two-component relativistic density-functional calculations of the dimers of the halogens from bromine through element 117 using effective core potential and all-electron methods.

    Science.gov (United States)

    Mitin, Alexander V; van Wüllen, Christoph

    2006-02-14

    A two-component quasirelativistic Hamiltonian based on spin-dependent effective core potentials is used to calculate ionization energies and electron affinities of the heavy halogen atom bromine through the superheavy element 117 (eka-astatine) as well as spectroscopic constants of the homonuclear dimers of these atoms. We describe a two-component Hartree-Fock and density-functional program that treats spin-orbit coupling self-consistently within the orbital optimization procedure. A comparison with results from high-order Douglas-Kroll calculations--for the superheavy systems also with zeroth-order regular approximation and four-component Dirac results--demonstrates the validity of the pseudopotential approximation. The density-functional (but not the Hartree-Fock) results show very satisfactory agreement with theoretical coupled cluster as well as experimental data where available, such that the theoretical results can serve as an estimate for the hitherto unknown properties of astatine, element 117, and their dimers.

  10. Grids of Agricultural Pesticide Use in the Conterminous United States, 1997

    Data.gov (United States)

    U.S. Geological Survey, Department of the Interior — This spatial dataset consists of 219 1-kilometer (km) resolution grids depicting estimated agricultural use of 219 pesticides in 1997 for the conterminous United...

  11. 77 FR 50631 - Homeland Security Acquisition Regulation (HSAR); Revision Initiative [HSAR Case 2009-002

    Science.gov (United States)

    2012-08-22

    ... Guarantee. (USCG) ----3052.219-70 Small Business Subcontracting Plan Reporting. ----3052.219-71 DHS Mentor.... ----3052.247-70 F.o.B. Origin Information. ----Alternate I ----Alternate II ----3052.247-71 F.o.B....

  12. 48 CFR 1819.7302 - NASA contract clauses.

    Science.gov (United States)

    2010-10-01

    ... to Public Law 97-219 (the Small Business Innovation Development Act of 1982). (b) Contracting... pursuant to Public Law 97-219 (the Small Business Innovation Development Act of 1982). (c) Contracting... Law 97-219 (the Small Business Innovation Development Act of 1982). (d) Contracting officers...

  13. R&D of φ1 219 mm X80 LSAW linepipe for No.2 west-east gas transmission pipeline projec%西气东输二线管道工程用X80钢级φ1219 mm直缝埋弧焊管的研发

    Institute of Scientific and Technical Information of China (English)

    李延丰

    2009-01-01

    介绍了西气东输二线管道工程用X80钢级φ1219 mm直缝埋弧焊管的研发情况.主要分析研究了X80钢级φ1219 mm直缝埋弧焊管的JCO成型、焊接、机械扩径、超声波自动探伤等技术;X80钢的理化性能试验结果;X80钢制管前后的拉伸性能、夏比冲击韧性、DWTT性能变化;X80钢级钢板夏比冲击韧性与温度的关系、屈强比的合理确定.

  14. Dietary exposure to benzoates (E210-E213), parabens (E214-E219), nitrites (E249-E250), nitrates (E251-E252), BHA (E320), BHT (E321) and aspartame (E951) in children less than 3 years old in France.

    Science.gov (United States)

    Mancini, F R; Paul, D; Gauvreau, J; Volatier, J L; Vin, K; Hulin, M

    2015-01-01

    This study aimed to estimate the exposure to seven additives (benzoates, parabens, nitrites, nitrates, BHA, BHT and aspartame) in children aged less than 3 years old in France. A conservative approach, combining individual consumption data with maximum permitted levels, was carried out for all the additives. More refined estimates using occurrence data obtained from products' labels (collected by the French Observatory of Food Quality) were conducted for those additives that exceeded the acceptable daily intake (ADI). Information on additives' occurrence was obtained from the food labels. When the ADI was still exceeded, the exposure estimate was further refined using measured concentration data, if available. When using the maximum permitted level (MPL), the ADI was exceeded for benzoates (1.94 mg kg(-1) bw day(-1)), nitrites (0.09 mg kg(-1) bw day(-1)) and BHA (0.39 mg kg(-1) bw day(-1)) in 25%, 54% and 20% of the entire study population respectively. The main food contributors identified with this approach were current foods as these additives are not authorised in specific infant food: vegetable soups and broths for both benzoates and BHA, delicatessen and meat for nitrites. The exposure estimate was significantly reduced when using occurrence data, but in the upper-bound scenario the ADI was still exceeded significantly by the age group 13-36 months for benzoates (2%) and BHA (1%), and by the age group 7-12 months (16%) and 13-36 months (58%) for nitrites. Measured concentration data were available exclusively for nitrites and the results obtained using these data showed that the nitrites' intake was below the ADI for all the population considered in this study. These results suggest that refinement of exposure, based on the assessment of food levels, is needed to estimate the exposure of children to BHA and benzoates for which the risk of exceeding the ADI cannot be excluded when using occurrence data.

  15. Development of Φ1219mm×22mm LSAW Pipe in Mo-containing X80 Steel Grade%Φ1 219mm×22mm X80钢级含Mo直缝埋弧焊管的开发

    Institute of Scientific and Technical Information of China (English)

    李延丰; 任毅; 陈小伟

    2008-01-01

    通过研制西气东输二线天然气管道工程用Φ1219mm×22mm X80钢级含Mo直缝埋弧焊管,研究了X80钢级含Mo钢板的焊接性、热影响区的弱化,并对矩形和圆棒拉伸试样进行了对比试验分析,对Φ1219mm×22mm X80钢级HTP与含Mo直缝埋弧焊管的主要性能进行了对比分析.提出了厚壁X80钢级管线钢管的拉伸试验应采用圆棒试样的建议.

  16. Alpha-decay studies of the new isotopes sup 1 sup 9 sup 1 At and sup 1 sup 9 sup 3 At

    CERN Document Server

    Kettunen, H; Grahn, T; Greenlees, P T; Jones, P; Julin, R; Juutinen, S; Keenan, A; Kuusiniemi, P; Leino, M; Leppaenen, A P; Nieminen, P; Pakarinen, J; Rahkila, P; Uusitalo, J

    2003-01-01

    Detailed alpha-decay studies have been performed for the neutron-deficient isotopes sup 1 sup 9 sup 1 At and sup 1 sup 9 sup 3 At. The nuclei were produced in fusion-evaporation reactions of sup 5 sup 4 Fe and sup 5 sup 6 Fe ions with a sup 1 sup 4 sup 1 Pr target. The fusion products were separated in-flight using a gas-filled recoil separator and implanted into a position-sensitive silicon detector. The isotopes were identified using position, time and energy correlations between the implants and subsequent alpha-decays. Three alpha-decaying states were identified for sup 1 sup 9 sup 3 At and two for sup 1 sup 9 sup 1 At. The spin and parity of the initial states in the astatine isotopes were deduced based on unhindered alpha-decays to states in the bismuth daughter nuclei. In both astatine isotopes the 1/2 sup + intruder state was determined to be the ground state and a 7/2 sup - state to be the first-excited state. In sup 1 sup 9 sup 3 At the alpha-decay of the 13/2 sup + state was observed in coincidence...

  17. EST Table: FS871503 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS871503 E_FL_fner_45K10_R_0 10/09/28 90 %/219 aa ref|NP_001036841.1| Annexin IX is...oform A [Bombyx mori] dbj|BAA92809.1| annexin IX-A [Bombyx mori] 10/09/11 73 %/219 aa FBpp0280989|DpseGA1909...1|gene:ANXB9 10/09/10 61 %/219 aa gnl|Amel|GB16448-PA 10/09/10 73 %/219 aa gi|91092420|ref|XP_967931.1| PREDICTED: similar to Annexin IX CG5730-PC [Tribolium castaneum] FS780436 fner ...

  18. 76 FR 55933 - Federal Property Suitable as Facilities To Assist the Homeless

    Science.gov (United States)

    2011-09-09

    ... Agency: Air Force Property Number: 18201130005 Status: Unutilized Directions: 219, 250, 1409, 1410, 1902... Newington NH 03803 Landholding Agency: Air Force Property Number: 18201130031 Status: Excess Reasons:...

  19. 75 FR 13265 - National Board for Education Sciences

    Science.gov (United States)

    2010-03-19

    .... ADDRESSES: 80 F Street, NW., Room 100, Washington, DC 20208. FOR FURTHER INFORMATION CONTACT: Norma Garza..., DC 20208; phone: (202) 219-2195; fax: (202) 219- 1466; e-mail: Norma.Garza@ed.gov . Individuals who...:30 p.m. A final agenda will be available from Norma Garza (see contact information above) on March...

  20. 75 FR 53280 - National Board for Education Sciences

    Science.gov (United States)

    2010-08-31

    ... CONTACT: Norma Garza, Executive Director, National Board for Education Sciences, 555 New Jersey Ave., NW., Room 602K, Washington, DC 20208; phone: (202) 219-2195; fax: (202) 219-1466; e-mail: Norma.Garza@ed.gov... alternative format) should notify Norma Garza no later than September 20. We will attempt to meet requests...

  1. 48 CFR 819.709 - Contract clause.

    Science.gov (United States)

    2010-10-01

    ... PROGRAMS SMALL BUSINESS PROGRAMS The Small Business Subcontracting Program 819.709 Contract clause. The contracting officer shall insert VAAR clause 852.219-9, Small Business Subcontracting Plan Minimum Requirements, in solicitations and contracts that include FAR clause 52.219-9, Small Business...

  2. Dicty_cDB: Contig-U14672-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available , Expect = 4e-19 Identities = 49/49 (100%) Strand = Plus / Plus Query: 171 ccaccaaagtttcanaccttgctatttattttt...aaatatattattctaa 219 ||||||||||||||||||||||||||||||||||||||||||||||||| Sbjct: 171 ccaccaaagtttcanaccttgctatt...ad. Length = 320 Score = 91.7 bits (46), Expect(3) = 3e-25 Identities = 49/49 (100%) Strand = Plus / Plus Query: 171 ccaccaaagtttcan...||||||||||||||||||||||||||||||| Sbjct: 171 ccaccaaagtttcanaccttgctatttatttttaaatatattattctaa 219 Score = 40.

  3. 75 FR 40019 - In the Matter of the Review of the Designation of the Communist Party of the Philippines/New...

    Science.gov (United States)

    2010-07-13

    ... Matter of the Review of the Designation of the Communist Party of the Philippines/New People's Army (aka... matter pursuant to Section 219(a)(4)(C) of the Immigration and Nationality Act, as amended (8 U.S.C. 1189... organization as a foreign terrorist organization, pursuant to Section 219 of the INA (8 U.S.C. 1189), shall...

  4. 78 FR 64929 - National Advisory Committee on Institutional Quality and Integrity (NACIQI)

    Science.gov (United States)

    2013-10-30

    ... December 13, 2013 from 8:00 a.m. to 5:30 p.m., at the Liaison Capitol Hill Hotel, 415 New Jersey Ave. NW... Griffiths, Executive Director, NACIQI, U.S. Department of Education, 1990 K Street NW., Room 8073, Washington, DC 20006-8129, telephone: (202) 219-7035, fax: (202) 219- 7005, or email:...

  5. 78 FR 51240 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Science.gov (United States)

    2013-08-20

    ... of Proposed Rule Change To Eliminate Rules Related to CYCLE Routing August 14, 2013. Pursuant to... Change The Exchange filed a proposal to eliminate Rules 11.13(a)(3)(A) and 21.9(a)(2)(A), which are the.... Purpose The Exchange is proposing to eliminate Rules 11.13(a)(3)(A) and 21.9(a)(2)(A), which are...

  6. One Year Oral Toxicity Study of WR238605 Succinate in Dogs. Volume 2

    Science.gov (United States)

    1997-07-18

    219 SEX: MALE Animal ID RBC HGB 10*6/IJITIA3 g/dL HCT HCV MCH MCHC % fL...PRTL219 Urinalvsis Qualitative Bilirubin Nitrite Glucose pH Ketones Protein Occult Blood Urobilinogen Leukocytes Color Specific Gravity

  7. 77 FR 54923 - Minor Boundary Revision at Big Thicket National Preserve

    Science.gov (United States)

    2012-09-06

    ... National Park Service Minor Boundary Revision at Big Thicket National Preserve AGENCY: National Park..., pursuant to the Act of October 11, 1974 (Pub. L. 93- 439, 88 Stat. 1245), the boundary of Big Thicket...; Tract 219-12, 6.45 acres; Tract 219- 13, 177.28 acres; Tract 221-15, 8.51 acres; Tract 221-16,...

  8. NASA/DoD Aerospace Knowledge Diffusion Research Project. Report Number 13. Source Selection and Information Use by U.S. Aerospace Engineers and Scientists: Results of a Telephone Survey

    Science.gov (United States)

    1992-09-01

    Aerospace Knowledge Diffusion Research Project. Government Information Quarterly 8(2), 219- 233. Shuchman, H. L. (1981). Information Transfer in...Research Project. Reprinted from Government Information Quarterly , Volume 8, No. 2 (1991): 219-233. (Available from AIAA 91A35455.) 1 1 Pinelli, Thomas

  9. Engineering Work and Information Use in Aerospace: Results of a Telephone Survey

    Science.gov (United States)

    1992-10-01

    and Rebecca 0. Barclay. "The NASA/DoD Aerospace Knowledge Diffusion Research Project." Government Information Quarterly 8.2 (1991): 219-233. Polanyi...Aerospace Knowledge Diffusion Research Project. Reprinteo .om Government Information Quarterly , Volume 8, No. 2 (1991): 219-233. (Available from AIAA

  10. NASA/DOD Aerospace Knowledge Diffusion Research Project. A Comparison of the Technical Communication Practices of Aerospace Engineers and Scientists in India and the United States

    Science.gov (United States)

    1993-09-01

    34The NASA/DoD Aerospace Knowledge Diffusion Research Project." Government Information Quarterly 8:2 (1991): 219-233. 35 APPENDIX A AEROSPACE KNOWLEDGE... Government Information Quarterly , Volume 8, No. 2 (1991): 219-233. (Available from AIAA 91A35455.) 1 1 Pinelli, Thomas E. and John M. Kennedy. The

  11. Technical Uncertainty and Project Complexity as Correlates of Information Use by U.S. Industry-Affiliated Aerospace Engineers and Scientists: Results of an Exploratory Investigation

    Science.gov (United States)

    1993-09-01

    Barclay. (1991). "The NASA/DoD Aerospace Knowledge Diffusion Research Project." Government Information Quarterly 8:2, 219-233. Randolph, W. Alan. (1978...from Government Information Quarterly , Volume 8, No. 2 (1991): 219-233. (Available from AIAA 91A35455.) 1 1 Pinelli, Thomas E. and John M. Kennedy

  12. 77 FR 76936 - Defense Federal Acquisition Regulation Supplement; Technical Amendments

    Science.gov (United States)

    2012-12-31

    ....1105; 4. Clarifies terminology at 204.7102 and 204.7106 relating to contract line items. 5. Updates...'' and adding ``datafax (571) 372-6094'' in its place. PART 203--IMPROPER BUSINESS PRACTICES AND PERSONAL.../ CPF'' and adding ``DPAP/CPIC'' in its place. PART 219--SMALL BUSINESS PROGRAMS 219.202-1 0 8....

  13. Dicty_cDB: Contig-U06096-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available |||||||||||| Sbjct: 64 gaaatngatgntncaacnccaacaatggctgcaaanattttttnnccnttttcaattggt 123 Query: 124 ggnaatgttggngatgntacaacnccna...ctt 154 ||||||||||||||||||||||||||||||| Sbjct: 124 ggnaatgttggngatgntacaacnccnactt 154 Sc...us Query: 219 atcncaacnatnncaacaacnaactgaatcagaattacnaccnattcaaa 268 |||||||||||||||||||||||||||||||||||||||...||||||||||| Sbjct: 219 atcncaacnatnncaacaacnaactgaatcagaattacnaccnattcaaa 268 >Contig-U11917-1 (Contig-U1191...atgntncaacnccaacaatggctgcaaanattttttnnccnttttcaattggt 147 Query: 124 ggnaatgttggngatgntacaacnccnacttnaaaanaa

  14. Comparecencia del señor director de la Cátedra de Accessibilidad, Arquitectura, Diseño y Tecnología para todos de la Universitat Politècnica de Catalunya, UPC (Guasch Murillo), para informar sobre temas relacionados con el objeto de la misma. A petición del grupo parlamentario catalán (Convergència i Unió). (Número de expediente 219/000320.)

    OpenAIRE

    Guasch Murillo, Daniel

    2010-01-01

    Transcripció de la intervenció en la comparescència del director de la Càtedra d'Accessibilitat, Arquitectura, Disseny i Tecnologia de la Universitat Politècnica, Daniel Guasch Murillo a la Comisión para las políticas integrales de la discapacidad al Congrès dels Diputats

  15. Modélisation pluie-débit en région tropicale humide : application des réseaux de neurones sur quatre stations hydrométriques du Bandama Blanc (Bada, Marabadiassa, Tortiya et Bou situées au Nord de la Côte d'Ivoire. Thèse de l'Université de Cocody (Côte d'Ivoire, 2007, 219 p.

    Directory of Open Access Journals (Sweden)

    Yao Blaise Koffi

    2009-12-01

    Full Text Available La relation pluie-débit fait l'objet de nombreuses études, à cause de son importance dans la mise en œuvre de nombreux projets de développement. La communauté scientifique, dans le souci de faire face aux problèmes d'eau, tels que les inondations et les sècheresses, utilise différents modèles. Mais ces modèles sont généralement confrontés à la non-linéarité de la relation pluie-débit. Dans le cas du Bandama Blanc, objet de cette étude, cette non-linéarité est accentuée par la présence de plusieurs barrages à vocation agro-pastorale situés dans la partie nord de la zone d'étude et qui utilisent les eaux de ce fleuve. Ce mémoire de thèse traite donc de la modélisation des débits mensuels du Bandama Blanc, aux stations de Bada, Marabadiassa, Tortiya et Bou, à l'aide des réseaux de neurones, déjà éprouvés dans ce contexte de relation non-linéaire. Elle projette de fournir des outils plus robustes aux hydrologues africains pour la simulation et la prévision des débits des rivières jaugées. Pour atteindre cet objectif, deux Perceptrons Multicouches entraînés avec l'algorithme de la rétropropagation de l'erreur ont été construits. Le premier modèle a été utilisé seulement en simulation et le second en simulation et en prévision. Le modèle conceptuel GR2M, a été utilisé pour valider les résultats obtenus avec les réseaux de neurones. Pour cette étude, une importante base de données climatiques (pluie et température et hydrométriques (débits mensuels a été utilisée. Les résultats obtenus sont forts satisfaisants et nettement supérieurs à ceux obtenus avec le modèle conceptuel global GR2M. En effet, les réseaux de neurones parviennent à expliquer plus de 70 % de la variation des débits, avec des coefficients de corrélation de Pearson qui excèdent 0,80. Cependant ces modèles arrivent difficilement à simuler et à faire la prévision des débits extrêmes (étiages et crues, à cause probablement du nombre réduit de données à notre disposition et de la séparation des bases de calage et de validation.The rainfall-runoff relationship is the subject of many studies because of its importance in the implementation of many development projects. The scientific community, in order to cope with water problems such as floods and droughts, used different models. But these models are usually faced with the non-linearity of the rainfall-runoff relationship. In the case of the Bandama Blanc purpose of this study, this non-linearity is enhanced by the presence of several agro-pastoral dams located in the northern part of the study area and using the waters of this river. This thesis therefore deals with the modeling of flows of Bandama Blanc hydrometric stations (Bada Marabadiassa, Tortiya and Bou using neural networks already experienced in the context of non-linear relationship. It plans to provide more robust tools to African hydrologist in the simulation and forecasting of river flows. To achieve this goal, two Multilayer Perceptrons trained with the backpropagation algorithm of error have been built. The first model was used only in simulation and the second in simulation and prediction. The conceptual model GR2M was used to validate the results obtained with neural networks. An extensive database climate (rainfall and temperature and river monthly flow was used in this study. The results obtained are very satisfactory and well above those obtained with the overall conceptual model GR2M. Indeed, neural networks are able to explain more than 70% of the variation in rates, with Pearson correlation coefficients exceeding 0.80. However, these models have difficulty to simulate and predict extremes flow probably because of the reduced number of data at our disposal and separation of bases calibration and validation.

  16. Is electronegativity a useful descriptor for the pseudo-alkali metal NH4?

    Science.gov (United States)

    Whiteside, Alexander; Xantheas, Sotiris S; Gutowski, Maciej

    2011-11-18

    Molecular ions in the form of "pseudo-atoms" are common structural motifs in chemistry, with properties that are transferrable between different compounds. We have determined one such property--the electronegativity--for the "pseudo-alkali metal" ammonium (NH(4)), and evaluated its reliability as a descriptor versus the electronegativities of the alkali metals. The computed properties of ammonium's binary complexes with astatine and of selected borohydrides confirm the similarity of NH(4) to the alkali metal atoms, although the electronegativity of NH(4) is relatively large in comparison to its cationic radius. We have paid particular attention to the molecular properties of ammonium (angular anisotropy, geometric relaxation and reactivity), which can cause deviations from the behaviour expected of a conceptual "true alkali metal" with this electronegativity. These deviations allow for the discrimination of effects associated with the molecular nature of NH(4).

  17. New developments of the in-source spectroscopy method at RILIS/ISOLDE

    CERN Document Server

    Marsh, B A; Imai, N; Seliverstov, M D; Rothe, S; Sels, S; Capponi, L; Rossel, R E; Franchoo, S; Wendt, K; Focker, G J; Kalaninova, Z; Sjoedin, A M; Popescu, L; Nicol, T; Huyse, M; Radulov, D; Atanasov, D; Kesteloot, N; Borgmann, Ch; Cocolios, T E; Lecesne, N; Ghys, L; Pauwels, D; Rapisarda, E; Kreim, S; Liberati, V; Wolf, R N; Andel, B; Schweikhard, L; Lane, J; Derkx, X; Kudryavtsev, Yu; Zemlyanoy, S G; Fedosseev, V N; Lynch, K M; Rosenbusch, M; Van Duppen, P; Lunney, D; Manea, V; Barzakh, A E; Andreyev, A N; Truesdale, V; Flanagan, K T; Molkanov, P L; Koester, U; Van Beveren, C; Wienholtz, F; Goodacre, T Day; Antalic, S; Bastin, B; De Witte, H; Fink, D A; Fedorov, D V

    2013-01-01

    At the CERN ISOLDE facility, long isotope chains of many elements are produced by proton-induced reactions in target materials such as uranium carbide. The Resonance Ionization Laser Ion Source (RILIS) is an efficient and selective means of ionizing the reaction products to produce an ion beam of a chosen isotope. Coupling the RILIS with modern ion detection techniques enables highly sensitive studies of nuclear properties (spins, electromagnetic moments and charge radii) along an isotope chain, provided that the isotope shifts and hyperfine structure splitting of the atomic transitions can be resolved. At ISOLDE the campaign to measure the systematics of isotopes in the lead region (Pb, Bi, Tl and Po) has been extended to include the gold and astatine isotope chains. Several developments were specifically required for the feasibility of the most recent measurements: new ionization schemes (Po, At); a remote controlled narrow line-width mode of operation for the RILIS Ti:sapphire laser (At, Au, Po); isobar fr...

  18. New developments of the in-source spectroscopy method at RILIS/ISOLDE

    Energy Technology Data Exchange (ETDEWEB)

    Marsh, B.A., E-mail: bruce.marsh@cern.ch [CERN, CH-1211 Geneva (Switzerland); Andel, B. [Comenius University, Bratislava (Slovakia); Andreyev, A.N. [University of York, Department of Physics, York YO10 5DD (United Kingdom); Antalic, S. [Comenius University, Bratislava (Slovakia); Atanasov, D. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Barzakh, A.E. [Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, 188300 Gatchina (Russian Federation); Bastin, B. [Grand Accérateur National d’Ions Lourds (GANIL), Bd Henri Becquerel, F-14076 Caen (France); Borgmann, Ch. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Capponi, L. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Cocolios, T.E.; Day Goodacre, T. [CERN, CH-1211 Geneva (Switzerland); University of Manchester, Manchester (United Kingdom); Dehairs, M. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Derkx, X. [University of the West of Scotland, School of Engineering, Paisley PA1 2BE (United Kingdom); De Witte, H. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Fedorov, D.V. [Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, 188300 Gatchina (Russian Federation); Fedosseev, V.N.; Focker, G.J. [CERN, CH-1211 Geneva (Switzerland); Fink, D.A. [Ruprecht-Karls Universität, Seminarstr. 2, 69117 Heidelberg (Germany); CERN, CH-1211 Geneva (Switzerland); Flanagan, K.T. [University of Manchester, Manchester (United Kingdom); Franchoo, S. [CSNSM-IN2P3-CNRS, Université Paris-Sud, 91406 Orsay (France); and others

    2013-12-15

    Highlights: • Upgrade of the lasers, detectors and data acquisition for in-source resonance ionization spectroscopy at ISOLDE. • First use of the ISOLTRAP MR-ToF MS in combination with laser spectroscopy at ISOLDE. • Resonance ionization of astatine for the study of its nuclear structure. -- Abstract: At the CERN ISOLDE facility, long isotope chains of many elements are produced by proton-induced reactions in target materials such as uranium carbide. The Resonance Ionization Laser Ion Source (RILIS) is an efficient and selective means of ionizing the reaction products to produce an ion beam of a chosen isotope. Coupling the RILIS with modern ion detection techniques enables highly sensitive studies of nuclear properties (spins, electromagnetic moments and charge radii) along an isotope chain, provided that the isotope shifts and hyperfine structure splitting of the atomic transitions can be resolved. At ISOLDE the campaign to measure the systematics of isotopes in the lead region (Pb, Bi, Tl and Po) has been extended to include the gold and astatine isotope chains. Several developments were specifically required for the feasibility of the most recent measurements: new ionization schemes (Po, At); a remote controlled narrow line-width mode of operation for the RILIS Ti:sapphire laser (At, Au, Po); isobar free ionization using the Laser Ion Source Trap, LIST (Po); isobar selective particle identification using the multi-reflection time-of-flight mass separator (MR-ToF MS) of ISOLTRAP (Au, At). These are summarized as part of an overview of the current status of the in-source resonance ionization spectroscopy setup at ISOLDE.

  19. An open-label study to assess the effect of a single dose of Nebivolol and Ivabradine on heart rate and pulse wave velocity in hypertensive patients receiving amlodipine

    Directory of Open Access Journals (Sweden)

    Rama Mohan Pathapati

    2015-04-01

    Conclusions: Nebivolol is an effective HR lowering agent compared to Ivabradine. However, significant decrease in arterial stiffness was observed with Ivabradine. [Int J Basic Clin Pharmacol 2015; 4(2.000: 219-223

  20. Oceanographic data acquired in support of the June 1980 study of the upwelling center off Point Sur, California (NODC Accession 9000024)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Current, Temperature and Depth (CTD) data were collected by Naval Postgraduate School from Coastal Waters of California between 2-19 June, 1980 using ship...

  1. 75 FR 28019 - Resmethrin; Notice of Receipt of Requests to Voluntarily Cancel Certain Pesticide Registrations

    Science.gov (United States)

    2010-05-19

    ..., recreational, and residential areas to control flying and crawling insects. All remaining resmethrin end use... reproduction 2.1.7 Hershberger (rat) 2.1.8 Female Pubertal (rat) 2.1.9 Male pubertal (rat)...

  2. Disease: H00116 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available H00116 Congenital lactase deficiency; Disaccharide intolerance II Congenital lactas...6060 Swallow DM Genetics of lactase persistence and lactose intolerance. Annu Rev Genet 37:197-219 (2003) ...

  3. 78 FR 36621 - Self-Regulatory Organizations; BATS Exchange, Inc.; Notice of Filing and Immediate Effectiveness...

    Science.gov (United States)

    2013-06-18

    ... of a Proposed Rule Change To Amend Rule 2.11, Entitled ``BATS Trading, Inc. as Outbound Router'' June... Trading, Inc. as Outbound Router'', and Rule 21.9, entitled ``Order Routing'', with respect to...

  4. 47 CFR 80.179 - Unattended operation.

    Science.gov (United States)

    2010-10-01

    ...-band direct-printing (NB-DP) operations in accordance with § 80.219. (c) Automatic use of a transmitter... selectively addressed to an individual station. (5) Transmitter output power must not exceed one watt. (6)...

  5. 78 FR 38442 - Notice of Receipt of Petition for Decision That Nonconforming 2005-2006 Mercedes Benz SLR...

    Science.gov (United States)

    2013-06-26

    ... language, and be no greater than 15 pages in length, although there is no limit to the length of necessary..., 216 Roof Crush Resistance, 219 Windshield Zone Intrusion, and 302 Flammability of Interior...

  6. 77 FR 70541 - Notice of Receipt of Petition for Decision That Nonconforming 2009 Porsche 911 (997) Passenger...

    Science.gov (United States)

    2012-11-26

    ... greater than 15 pages in length, although there is no limit to the length of necessary attachments to the... Resistance, 219 Windshield Zone Intrusion, 225 Child Restraint Anchorage Systems, and 302 Flammability...

  7. 77 FR 67732 - Notice of Receipt of Petition for Decision That Nonconforming 2009 Porsche Cayenne S Multipurpose...

    Science.gov (United States)

    2012-11-13

    ... language, and be no greater than 15 pages in length, although there is no limit to the length of necessary... Resistance, 219 Windshield Zone Intrusion, 225 Child Restraint Anchorage Systems, and 302 Flammability...

  8. 77 FR 17567 - Notice of Receipt of Petition for Decision That Nonconforming Right-Hand Drive 2000-2003 Jeep...

    Science.gov (United States)

    2012-03-26

    ... language, and be no greater than 15 pages in length, although there is no limit to the length of necessary... Resistance, 219 Windshield Zone Intrusion, and 302 Flammability of Interior Materials. The petitioner...

  9. 75 FR 19461 - Receipt of Petition for Decision That Nonconforming 2006 and 2007 Mercedes Benz G-Class Long...

    Science.gov (United States)

    2010-04-14

    ... greater than 15 pages in length, although there is no limit to the length of necessary attachments to the... Resistance, 219 Windshield Zone Intrusion, 301 Fuel System Integrity, and 302 Flammability of...

  10. 78 FR 77710 - National Register of Historic Places; Notification of Pending Nominations and Related Actions

    Science.gov (United States)

    2013-12-24

    ...., Bridgeport, 13001049 Brown--Henry House, 818 Fields Ave., Frankfort, 13001050 Point Breeze, 219 Riverview St... Madison County Churchill Weavers, 100 Churchill Dr., Berea, 13001054 Trimble County Norfolk Farm...

  11. Gene : CBRC-ACAR-01-0376 [SEVENS

    Lifescience Database Archive (English)

    Full Text Available 219.3| AGAP008244-PA [Anopheles gambiae str. PEST] gb|EAL39610.3| AGAP008244-PA [Anopheles gambiae str. PEST...GTIAGTSESPRAQETTSLKSTKTPTSESTTLSETTSLERTIEGISESTVVQETTSLETTTAATTLSSRAQEITSPESTKIP...TSESTTLSETTSSESAMSATTESPRAQETTSPDITTAATSESTTLSEKTSPESTIAGTSQSTVVQETTSPEGTIAATSESPKAQETTSPESTKTAASESTPLPKTVSPEST...ITGRSESTIVQETTSPDGTTAATSESTVVQETTSPESTTAATSESPRAQETTSPESTTAATPESSKLSETTSPESTIAGTSQSTVVQETTSPDSTTAATSESQRAHKTTSPEST...KTAKSESTTVSVTISPECTIAGTSESTVVQKNTFPESTTAATSESTPLSETTSPESTIARTSESIVVQETTSPEST

  12. Symmetry adaptation of spherical tensor quantities in cubic point groups: comments on a paper by M. Rey et al.

    Science.gov (United States)

    Michelot, F.

    2004-04-01

    We underline some inconsistencies in the work [J. Mol. Spectrosc. 219 (2003) 313] concerning symmetry adaptation in cubic groups. Also we show that some rather complicated methods presented can be easily avoided.

  13. Doctoral Theses in Library and Information Science Completed in Indian Universities, 2001-2007

    Science.gov (United States)

    Mestri, D. D.

    2008-01-01

    Provides a complete listing and analysis of 219 doctoral theses submitted to the departments of library and information science (DLIS) in 45 Indian universities between January 2001 and December 2007. (Contains 10 tables.)

  14. 76 FR 44394 - Public Transportation on Indian Reservations Program; Tribal Transit Program

    Science.gov (United States)

    2011-07-25

    ... 20006, Tel. 202-219- Northern Mariana Islands. 3562. Los Angeles Metropolitan Yvette Taylor, Regional Administrator, Office, Region 9-Los Angeles, Region 4-Atlanta, 230 Peachtreet 888 S. Figueroa Street,...

  15. Ühiskonna kihistumine kui raskendav tegur riigi suhtlemisel rahvaga / Agu Uudelepp

    Index Scriptorium Estoniae

    Uudelepp, Agu, 1974-

    2002-01-01

    Bibliogr. lk. 219. Poliitikud peaksid rahvaga rääkides arvestama 4 etappi: veenmise eeltöö, usaldusväärsuse saavutamine, sõnumi koostamine ja edastamisviisi valimine ning emotsioonide äratamine

  16. Prevalence of gestational diabetes mellitus, its associated risk factors and pregnancy outcomes at a rural setup in Central India

    Directory of Open Access Journals (Sweden)

    Kanika R. Kalyani

    2014-02-01

    Conclusion: GDM adversely affects maternal and fetal outcomes and its prevalence is steadily rising. Appropriate interventions are required for its control. [Int J Reprod Contracept Obstet Gynecol 2014; 3(1.000: 219-224

  17. FastStats: Sinus Conditions

    Science.gov (United States)

    ... please visit this page: About CDC.gov . FastStats Homepage Diseases and Conditions Anemia or Iron Deficiency Arthritis ... Statistics Tables for U.S. Adults: National Health Interview Survey, 2014, Table A-2 [PDF - 219 KB] Physician ...

  18. 76 FR 69801 - Conductor Certification

    Science.gov (United States)

    2011-11-09

    ... definition of ``conductor'' is a fundamental element of the conductor certification regulation and FRA does... and 219. G. Vision and Hearing Acuity BLET/UTU commented that proposed Sec. 242.117(k) should...

  19. Drug: D09952 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available ACE VTHQGLSSPV TKSFNRGEC (Disulfide bridge: 23-93; 139-199; H130-L219, Dimer) Peptide Treatment of Alzheim...er's disease monoclonal antibody beta-amyloid CAS: 1178862-65-1 PubChem: 124490631 ...

  20. Dicty_cDB: SFH109 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available musculus cDNA clone IMAGE:3468576 3', mRNA sequence. 38 0.11 2 CF390442 |CF390442.1 RTDR2_19_F09.g1_A021 Loblolly pine roots recover...ing from drought DR2 Pinus taeda cDNA clone RTDR2_19_F09_A021 5', mRNA sequence. 34

  1. BRAC-Mandated Military Airfield Closures: Short and Long-Term Economic Impacts on Small and Medium-Sized Communities

    Science.gov (United States)

    2012-02-15

    Pickaway 1,009,692 Mather AFB , CA Sacramento 1,041,219 McClellan AFB , CA Sacramento 1,041,219 S. Weymouth NAS, MA Norfolk / Plymouth 1,051,363...Biography Lieutenant Colonel Bret D. Anderson is a U.S. Air Force fighter pilot attending the Air War College, Air University, Maxwell AFB , Alabama. He...this period – for example, Newark AFB , Ohio. Bases 9 Peter Stenberg and Thomas D. Rowley, “A

  2. AcEST: DK954327 [AcEST

    Lifescience Database Archive (English)

    Full Text Available --SSSGLSLQDQATRKTIYGPNVISIP 219 Query: 308 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSIS...11%) Frame = +2 Query: 287 PSSPSVSAPQKLSILA------SALNGCQPNYKPSIRASLYYPFEPYSISLVHL 430 P P + A Q+ ++A S L+ P ...|B3PRV4_RHIE6 Putative metalloprotease protein OS=Rhizo... 34 6.3 tr|B8CBD2|B8CBD2_THAPS Predicted protein OS=Thalassiosira...QAFCQVSLLDHSRTCDDVHC-----SSSGLSLQDQATRKTIYGPNVISIP 211 Query: 308 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSISL 42...Sbjct: 165 GQRYVWMETQQAFCQVSLLDHGRTCDDVHC-----SSSGLSLQDQATRKTIYGPNVISIP 219 Query: 308 APQKLSILA-SALNGCQPNYKPSIRA

  3. Mechanisms of protein sequence divergence and incompatibility.

    Directory of Open Access Journals (Sweden)

    Alon Wellner

    Full Text Available Alignments of orthologous protein sequences convey a complex picture. Some positions are utterly conserved whilst others have diverged to variable degrees. Amongst the latter, many are non-exchangeable between extant sequences. How do functionally critical and highly conserved residues diverge? Why and how did these exchanges become incompatible within contemporary sequences? Our model is phosphoglycerate kinase (PGK, where lysine 219 is an essential active-site residue completely conserved throughout Eukaryota and Bacteria, and serine is found only in archaeal PGKs. Contemporary sequences tested exhibited complete loss of function upon exchanges at 219. However, a directed evolution experiment revealed that two mutations were sufficient for human PGK to become functional with serine at position 219. These two mutations made position 219 permissive not only for serine and lysine, but also to a range of other amino acids seen in archaeal PGKs. The identified trajectories that enabled exchanges at 219 show marked sign epistasis - a relatively small loss of function with respect to one amino acid (lysine versus a large gain with another (serine, and other amino acids. Our findings support the view that, as theoretically described, the trajectories underlining the divergence of critical positions are dominated by sign epistatic interactions. Such trajectories are an outcome of rare mutational combinations. Nonetheless, as suggested by the laboratory enabled K219S exchange, given enough time and variability in selection levels, even utterly conserved and functionally essential residues may change.

  4. Development of Reagents for Application of At-211 to Targeted Radionuclide Therapy of Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, D. Scott

    2011-12-23

    This grant covered only a period of 4 months as the major portion of the award was returned to DOE due to an award of funding from NIH that covered the same research objectives. A letter regarding the termination of the research is attached as the last page of the Final Report. The research conducted was limited due to the short period of this grant, but the results obtained in that period are outlined in the Final Report. The studies addressed in the research effort were directed at a problem that is of critical importance to the in vivo application of the alpha-particle emitting radionuclide At-211. That problem, low in vivo stability of many astatinated molecules, severely limits the use of At-211 in therapeutic applications. The advances sought in the studies were expected to expand the types of biomolecules that can be used as carriers of At-211, and provide improved in vivo targeting of the radiation dose compared with the dose delivered to normal tissue.

  5. Combined effect of gefitinib ('Iressa', ZD1839) and targeted radiotherapy with {sup 211}At-EGF

    Energy Technology Data Exchange (ETDEWEB)

    Sundberg, Aasa Liljegren; Orlova, Anna; Gedda, Lars; Tolmachev, Vladimir; Carlsson, Joergen [Division of Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala University, 751 85, Uppsala (Sweden); Almqvist, Ylva [Division of Radiology, Uppsala University, Uppsala (Sweden); Blomquist, Erik [Division of Oncology, Uppsala University, Uppsala (Sweden); Jensen, Holger J. [Department of Clinical Physiology and Nuclear Medicine, PET and Cyclotron Unit, Rigshospitalet, Copenhagen (Denmark)

    2003-10-01

    The EGFR-TKI (epidermal growth factor receptor tyrosine kinase inhibitor) gefitinib ['Iressa' (trademark of the AstraZeneca group of companies), ZD1839] increases the cellular uptake of radiolabelled epidermal growth factor (EGF). We investigated gefitinib treatment combined with astatine-211 EGF targeting in vitro using two cell lines expressing high levels of EGFR: A431 (sensitive to gefitinib) and U343MGaCl2:1 (resistant to gefitinib). In both cell lines, the uptake of {sup 211}At-EGF was markedly increased by concomitant treatment with gefitinib. Survival was investigated using both a clonogenic survival assay and a cell growth assay. Combined gefitinib and {sup 211}At-EGF treatment reduced the survival of U343 cells 3.5-fold compared with {sup 211}At-EGF alone. In A431 cells, {sup 211}At-EGF treatment resulted in very low survival, but combined treatment with gefitinib increased the survival by about 20-fold. These results indicate that combined treatment with gefitinib might increase the effect of ligand-mediated radionuclide therapy in gefitinib-resistant tumours and decrease the effect of such therapy in gefitinib-sensitive tumours. (orig.)

  6. Effect of cetuximab in combination with alpha-radioimmunotherapy in cultured squamous cell carcinomas

    Energy Technology Data Exchange (ETDEWEB)

    Nestor, Marika, E-mail: marika.nestor@bms.uu.s [Unit of Otolaryngology and Head and Neck Surgery, Department of Surgical Sciences, Uppsala University, S-751 85 Uppsala (Sweden); Unit of Biomedical Radiation Sciences, Department of Oncology, Radiology and Clinical Immunology, Uppsala University, S-751 85 Uppsala (Sweden); Sundstroem, Magnus [Unit of Molecular Pathology, Department of Genetics and Pathology, Uppsala University (Sweden); Anniko, Matti [Unit of Otolaryngology and Head and Neck Surgery, Department of Surgical Sciences, Uppsala University, S-751 85 Uppsala (Sweden); Tolmachev, Vladimir [Unit of Biomedical Radiation Sciences, Department of Oncology, Radiology and Clinical Immunology, Uppsala University, S-751 85 Uppsala (Sweden)

    2011-01-15

    Aim: The monoclonal antibody cetuximab, targeting the epidermal growth factor receptor (EGFR), is a promising molecular targeting agent to be used in combination with radiation for anticancer therapy. In this study, effects of cetuximab in combination with alpha-emitting radioimmunotherapy (RIT) in a panel of cultured human squamous cell carcinomas (SCCs) were assessed. Methods: SCC cell lines were characterized and treated with cetuximab in combination with anti-CD44v6 RIT using the astatinated chimeric monoclonal antibody U36 ({sup 211}At-cMAb U36). Effects on {sup 211}At-cMAb U36 uptake, internalization and cell proliferation were then assessed in SCC cells. Results: Cetuximab in combination with {sup 211}At-cMAb U36 mediated increased growth inhibition compared to RIT or cetuximab alone in two cell lines. However, cetuximab also mediated radioprotective effects compared to RIT alone in two cell lines. The radioprotective effects occurred in the cell lines in which cetuximab clearly inhibited cell growth during radiation exposure. Cetuximab treatment also influenced {sup 211}At-cMAb-U36 uptake and internalization, suggesting interactions between CD44v6 and EGFR. Conclusions: Results from this study demonstrate the vast importance of further clarifying the mechanisms of cetuximab and radiation response, and the relationship between EGFR and suitable RIT targets. This is important not only in order to avoid potential radioprotective effects, but also in order to find and utilize potential synergistic effects from these combinations.

  7. Cyclotron production of cesium radionuclides as analogues for francium-221 biodistribution

    Science.gov (United States)

    Finn, R.; McDevitt, M.; Sheh, Y.; Lom, C.; Qiao, J.; Cai, S.; Burnazi, E.; Nacca, A.; Pillarsetty, N.; Jaggi, J.; Scheinberg, D.

    2005-12-01

    In our clinical investigations focussing on improved therapeutic treatment of specific tumors we have concentrated on a targeted therapy approach utilizing designed radiolabeled monoclonal antibodies as the cytotoxic reagent. The physical characteristics of the alpha particle emitting radionuclide bismuth-213 including the short half-life of 45.6 min, has shown promise for the treatment of specific cancers such as leukemias and lymphomas or micrometastatic carcinomas. In an effort to increase the cytocidal effect of the HuM195, a humanized monoclonal antibody carrier to the CD33 antigen expressed on leukemia cells, our focus is directed toward an "internal" nano-generator composed of Ac-225 radionuclide, the parent of the bismuth-213. The actinium-225 radionuclide decays through several short-lived, alpha emitting daughters including francium-221, astatine-217 and bismuth-213. In order to study the biodistribution and the pharmacokinetics of the individual daughter nuclide, francium-221, the cyclotron production and separation of cesium radionuclides, specifically cesium-132, from a natural xenon gas target was undertaken. The choice of cesium as an analogue for francium was predicated upon both elements being in Group 1A alkali metals and cesium radionuclide possesses a sufficient half-life to allow biodistribution studies to be performed. The preliminary experimental results of this investigation are presented.

  8. Tumor Immunotargeting Using Innovative Radionuclides

    Directory of Open Access Journals (Sweden)

    Françoise Kraeber-Bodéré

    2015-02-01

    Full Text Available This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality.

  9. Study of Neutron-Deficient $^{202-205}$Fr Isotopes with Collinear Resonance Ionization Spectroscopy

    CERN Document Server

    De Schepper, Stijn; Cocolios, Thomas; Budincevic, Ivan

    The scope of this master’s thesis is the study of neutron-deficient $^{202−205}$Fr isotopes. These isotopes are inside the neutron-deficient lead region, a region that has shown evidence of shape coexistence. For this thesis, this discussion is limited to the phenomenon where a low lying excited state has a different shape than the ground state. Shape coexistence is caused by intruder states. These are single-particle Shell Model states that are perturbed in energy due to the interaction with a deformed core. In the neutron-deficient lead region the main proton intruder orbit is the 3s$_{1/2}$orbit. When going towards more neutron-deficient isotopes, deformation increases. The $\\pi3s_{1/2}$orbit will rise in energy and will eventually become the ground state in odd- A bismuth (Z=83) isotopes. It is also observed in odd-A astatine (Z=85) isotopes, already in less neutron-deficient nuclei. The same phenomenon is expected to be present francium (Z=87) isotopes already at $^{199}$Fr. Although it is currently ...

  10. Metalloids, soil chemistry and the environment.

    Science.gov (United States)

    Lombi, Enzo; Holm, Peter E

    2010-01-01

    This chapter reviews physical chemical properties, origin and use ofmetalloids and their relevance in the environment. The elements boron (B), silicon (Si), germanium (Ge), arsenic (As), antimony (Sb), tellurium (Te), polonium (Po) and astatine (At) are considered metalloids. Metalloids conduct heat and electricity intermediate between nonmetals and metals and they generally form oxides. The natural abundance ofmetalloids varies from Si being the second most common element in the Earth's crust to At as the rarest of natural elements on Earth. The metalloid elements Ge, Te, Po and At are normally present in trace or ultratrace levels in the environment and as such are not considered of relevance in terms of environmental health. The environmental geochemical processes, factors and parameters controlling the partitioning and the speciation of B, Si, As and Sb are reviewed in relation to the bioavailability of these metalloids. Approaches based on the hypothesis that metal toxicity is related to both the metal-ligand complexation processes and the metal interactions with competing cations at the cell surface (biotic ligand) have so far not been successful for assessing metalloid bioavailability. The chapter concludes that our understanding of metalloids toxicity will improve in the future if, in addition to the points discussed above, surface membrane potentials are considered. This should represent a robust approach to the prediction of metalloid toxicity.

  11. SPECT assay of radiolabeled monoclonal antibodies. Progress report, September 1, 1992--August 24, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Jaszczak, R.J.

    1993-08-20

    The overall goal of this project is to improve the effectiveness of single photon emission computed tomography (SPECT) to image and quantify radiolabeled monoclonal antibodies. During the past year, we have made significant progress toward this goal, and this report summarizes that work. Our efforts have been mainly directed along three fronts. First, we have developed and tested new reconstruction methods including three-dimensional iterative algorithms that model non-uniform attenuation and distance-dependent detector response. Both fan beam and parallel beam collimator geometries have been modeled and novel ways of improving the efficiency of the computationally intensive methods have been introduced. Second, an ultra-high resolution, small field-of-view pinhole collimator has been constructed and evaluated. Reconstructed spatial resolution of 1 to 3 mm (FWHM) has been achieved in phantom scans with a useful field-of-view of 9 to 10 cm. Finally, we have investigated the ability of SPECT to image and quantify astatine-211 distributions. Reconstructed images of phantom data demonstrated quantitative accuracy to within 10% with proper attenuation and scatter compensation.

  12. Glomerular filtration rate after alpha-radioimmunotherapy with 211At-MX35-F(ab')2: a long-term study of renal function in nude mice

    DEFF Research Database (Denmark)

    Back, T.; Haraldsson, B.; Hultborn, R;

    2009-01-01

    and animals bearing subcutaneous xenografts of the human ovarian cancer cell line, OVCAR-3, were used. The animals received approximately 0.4, 0.8, or 1.2 MBq in one, two, or three fractions. The mean absorbed doses to the kidneys ranged from 1.5 to 15 Gy. The renal function was studied by serial GFR...... of the glomerular filtration rate (GFR). The renal toxicity was evaluated at levels close to the dose limit for the bone marrow and well within the range for therapeutic efficacy on tumors. Astatinated MX35-F(ab')(2) monoclonal antibodies were administered intravenously to nude mice. Both non-tumor-bearing animals...... manifested late. Examination of the kidney sections showed histologic changes that were overall subdued. Following alpha-RIT with (211)At-MX35-F(ab')(2) at levels close to the dose limit of severe myelotoxicity, the effects found on renal function were relatively small, with only minor to moderate reductions...

  13. Silver impregnated nanoparticles of titanium dioxide as carriers for {sup 211}At

    Energy Technology Data Exchange (ETDEWEB)

    Cedrowska, Edyta; Lyczko, Monika; Piotrowska, Agata; Bilewicz, Aleksander [Institute of Nuclear Chemistry and Technology, Warsaw (Poland); Stolarz, Anna; Trcinska, Agnieszka [Warsaw Univ. (Poland). Heavy Ion Lab.; Szkliniarz, Katarzyna [Silesia Univ. Katowice (Poland). Inst. of Physics; Was, Bogdan [Polish Academy of Science, Cracow (Poland). Inst. of Nuclear Physics

    2016-08-01

    The {sup 211}At radioisotope exhibits very attractive nuclear properties for application in radionuclide therapy. Unfortunately use of {sup 211}At is limited, because astatine as the heaviest halogen forms weak bond with carbon atoms in the biomolecules which makes {sup 211}At bioconjugates unstable in physiological conditions. In our work we propose a new solution for binding of {sup 211}At which consists of using nanoparticles of titanium dioxide modified with silver atoms as carriers for {sup 211}At. Ag{sup +} cations have been absorbed on the nanometer-sized TiO{sub 2} particles (15 and 32 nm) through ion exchange process and were reduced in Tollens' reaction. The obtained TiO{sub 2}-Ag nanoparticles were labeled with {sup 211}At. It was found that labeling yields were almost quantitative under reducing conditions, while under oxidizing conditions they dropped to about 80%. The labeled nanoparticles exhibited very high stability in physiological salt, PBS buffer, solutions of peptides (0.001 M cysteine, 0.001 M glutathione) and in human blood serum. To make TiO{sub 2}/Ag nanoparticles well dispersed in water and biocompatible their surface was modified with a silane coupling agent containing poly(ethyleneglycol) molecules. The developed functionalization approach will allow us to attach biomolecules to the TiO{sub 2}/Ag surface.

  14. Studies of Stable Octupole Deformations in the Radium Region

    CERN Multimedia

    2002-01-01

    The purpose of the present project is to locate and identify states in the atomic nuclei possessing stable pearshaped octupole deformation. Such states, formally related to the structures known in molecular physics, manifest themselves as families of parity doublets in odd nuclei.\\\\ \\\\ The best possibilities for observing stable octupole deformations are offered in the Ra-region. Both theoretical calculations and experimental indications support such expectations. Such indications are the non-observation of two-phonon octupole vibrational states in the ISOLDE studies of the even-even radium nuclei, and the reversed sign of the decoupling factor of the ground state band in |2|2|5Ra observed in the single-neutron transfer reactions. In order to establish the predicted strong E1 and E3-transitions between the parity doublets in odd nuclei with stable octupole deformations it is proposed to study conversion electrons in odd-mass francium radium and radon isotopes following the @b-decay of francium and astatine. \\...

  15. Alpha particle emitters in medicine

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, D.R.

    1989-09-01

    Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical applications of alpha emitters. In recent years, however, the potential use of antibodies labeled with alpha emitting radionuclides against cancer has seemed promising because alpha particles are highly effective in cell killing. High dose rates at high LET, effectiveness under hypoxic conditions, and minimal expectancy of repair are additional advantages of alpha emitters over antibodies labeled with beta emitting radionuclides for cancer therapy. Cyclotron-produced astatine-211 ({sup 211}At) and natural bismuth-212 ({sup 212}Bi) have been proposed and are under extensive study in the United States and Europe. Radium-223 ({sup 223}Ra) also has favorable properties as a potential alpha emitting label, including a short-lived daughter chain with four alpha emissions. The radiation dosimetry of internal alpha emitters is complex due to nonuniformly distributed sources, short particle tracks, and high relative specific ionization. The variations in dose at the cellular level may be extreme. Alpha-particle radiation dosimetry, therefore, must involve analysis of statistical energy deposition probabilities for cellular level targets. It must also account fully for nonuniform distributions of sources in tissues, source-target geometries, and particle-track physics. 18 refs., 4 figs.

  16. Elsevier收录材料科学类期刊可开放获取情况的调查与分析

    Institute of Scientific and Technical Information of China (English)

    何燕; 瞿其春; 张雪娟

    2014-01-01

    对Elsevier旗下的SDOL数据库中的219种材料科学类期刊进行有关OA方面的研究,调查发现,在OSD和DOAJ这两大OA平台上,这219种期刊的可OA情况不容乐观。在SDOL数据库中,可OA的材料科学类期刊种数为数不少,但其中可OA期刊全文的并不多。将这219种期刊区分为完全OA期刊、部分OA期刊和完全非OA期刊,并对其质量进行了对比研究,认为Elsevier中材料科学类期刊的OA情况不是十分乐观,需业界的进一步推动。

  17. Clinical evaluation of Xive implants 3-year after placement

    Institute of Scientific and Technical Information of China (English)

    Ruixia Wang; Hua Yuan; Ning Chen; Guoping Wang; Zhaoping Fang; Guoxing Zhou

    2008-01-01

    Objective: The main purpose of this retrospective study is to evaluate clinical outcomes of Xive implants 3-year after insertion. Methods: 219 Xive implants were placed in 139 patients and their clinical effects were evaluated using the Albrektsson Standard. Results:The 3-year survival rate of the Xive implants is 97.26%(213/219). Eleven cases of immediate implants and 15 cases of implant insertion after maxillary sinus lifting all succeeded. The failure ratio is 6/219(2.74%) with failures resulting from excess bone loss in the implant region, peal-implant mucosal inflammation or continuous pain caused by some unknown reasons. Conclusion: Xive implants are clinically effective for the restoration of missing teeth. Immediate implant and implant following maxillary sinus lifting were also successful.

  18. Academic Research Vessels 1985-1990.

    Science.gov (United States)

    1982-01-01

    0.2 0.05 0.1 EPA 0.1 0.1 0.01 0.1 0.01 NASA 0.08 0.2 ARPA 0.4 State & Private 0.6 1.2 0.9 1.5 1.5 Totals* 21.9 22.8 21.9 25.6 29.4 * Cost of operating...This include no provision for crew layoff . The crew costs for an OCEANUS class vessel are approximately $310,000 for a crew of 12 4 persons. If one

  19. Determination of the Ionosphere Parameters by Analyzing the Propagation After-Effects

    Science.gov (United States)

    2010-06-27

    is a very “lively” medium; its characteristics depend on many factors , such as time of the day, time of the year, geographic location, level of Solar...whereas the long waves are subject to stronger dispersion. Indeed, the phase and group velocity of the propagation are given by: vph = c ( 1 + ω2pe/c...c) |x − y |2 . (2.19) The filter is essentially a complex conjugate of ψ1 given by (2.19); for simplicity, the constant factor −ω20/16π2, as well the

  20. Joint Services Electronics Program Progress Report.

    Science.gov (United States)

    1982-09-30

    Microwave Theory and Techniques, MTT-23, 781, 1975. (3) Y. Taur, J. H. Claassen, and P. L. Richards , IEEE Trans. Microwave Theory and Technioues, MTT-22...Jr., IEEE Trans. Magn., MAG-13, 221, 1977. (8) P. L. Richards , IEEE Trans. Electron Devices, ED-27, 1909, October 1980. (9) F. R. Arams, E. W. Sard...Communication and Electronics, pp. 219-224, March 1964. B9 j. W. Bandler and P. C. Liu, IEEE Trans. on Circuits and Systems, pp. 219-222, March 1974. ISS-83

  1. Department of Defense, Atlas/Data Abstract for the United States and Selected Areas, Fiscal Year 1997

    Science.gov (United States)

    1997-01-01

    8217T015DALE \\ THE DALLES CLACKAMAS CASCADE LOCKS * GLADSTONE *McMINNVILLE SALEM S ALBANY OCORVALLIS S EUGENE O LOWELL COOS BAY •CHARLESTON * TRAIL * GRANTS...Kingsley Field AGS 316 186 130 Beaverton 35,806 10,080 25,726 Salem 270 24 246 Hermiston 24,203 8,420 15,783 Hermiston 219 0 219 Eugene 23,491 20,462...Guard Services 21,946 5. SHINIL ENGINEERING CO LTD CHOO 21,692 Troop Housing Facilities 19,113 Total of Above $288,791 ( 51.1% of total awards over

  2. Corrosion Control in the US Navy: Ships & USMC Vehicles

    Science.gov (United States)

    2014-11-18

    Mr. Matthew Koch Corrosion Control & Prevention Executive Presented by E. Dail Thomas II, Consultant 18 November 2014 Corrosion Control in...control number. 1. REPORT DATE 18 NOV 2014 2. REPORT TYPE 3. DATES COVERED 00-00-2014 to 00-00-2014 4. TITLE AND SUBTITLE Corrosion Control in...Cost of Corrosion : $21.9B 2 DoD $21.9B $7.5B $5.1B $5.1B $0.3B $4.2B Other DoD U.S. Department of Defense Corrosion Organization 3 ASD

  3. Monolithic Hybrid and Passive Mode-Locked 40GHz Quantum Dot Laser Diodes

    DEFF Research Database (Denmark)

    Thompson, M. G.; Larsson, David; Rae, A. R.;

    2006-01-01

    For the first time hybrid and passive mode-locking jitter performance is investigated in 40GHz quantum-dot mode-locked lasers. Record low passive mode-locking jitter of 219fs is presented, along with promising hybrid mode-locking results of 124fs.......For the first time hybrid and passive mode-locking jitter performance is investigated in 40GHz quantum-dot mode-locked lasers. Record low passive mode-locking jitter of 219fs is presented, along with promising hybrid mode-locking results of 124fs....

  4. AcEST: DK959257 [AcEST

    Lifescience Database Archive (English)

    Full Text Available TCDDVHC-----SSSGLSLQDQATRKTIYGPNVISIP 219 Query: 391 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSISL 504 L +LA ALN Y... (51%), Gaps = 6/54 (11%) Frame = +1 Query: 370 PSSPSVSAPQKLSILA------SALNGCQPNYKPSIRA...alloprotease protein OS=Rhizo... 34 6.7 tr|B8CBD2|B8CBD2_THAPS Predicted protein OS=Thalassiosira pseudo... ...y: 391 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSISL 504 L +LA ALN YY F+ +SI+L Sbjct: 212 VKSYLQLLADEALNP---------...TIYGPNVISIP 219 Query: 391 APQKLSILA-SALNGCQPNYKPSIRASLYYPFEPYSISL 504 L +LA ALN YY F+ +SI+L Sbjct: 220 VKSY

  5. Resposta de plantas micropropagadas de abacaxizeiro à inoculação de bactérias diazotróficas em casa de vegetação Response of pineapple plantlets to inoculation with diazotrophic bacteria in greenhouse

    Directory of Open Access Journals (Sweden)

    Olmar Baller Weber

    2003-12-01

    Full Text Available O objetivo deste trabalho foi selecionar e avaliar bactérias diazotróficas isoladas de abacaxizeiro (Ananas comosus (L. Merril no desenvolvimento de cultivares micropropagadas da mesma espécie em casa de vegetação. Plantas da cultivar Perolera foram submetidas à inoculação com Asaia bogorensis (AB219 e cultivadas em tubetes, durante 145 dias, com as misturas: casca de arroz carbonizada, folha de carnaubeira triturada e vermicomposto; casca de arroz carbonizada, pó da casca do coco maduro e vermicomposto; casca de arroz carbonizada, vermiculita e vermicomposto. Plantas da cultivar Primavera receberam inóculos com o AB219 e bactérias relacionadas a Burkholderia cepacia (AB202 e AB213, enquanto plantas das cultivares Pérola e Smooth Cayenne receberam AB219 e AB213, sendo cultivadas, por 140 dias, em tubetes com a mistura de vermicomposto e vermiculita. A colonização dos abacaxizeiros pelas bactérias diazotróficas foi confirmada. As plantas da cultivar Perolera cresceram melhor em casca de arroz carbonizada, vermiculita e vermicomposto e responderam positivamente ao AB219. Já as plantas da cultivar Primavera não apresentaram resposta significativa à inoculação com AB219, AB202 e AB213. Houve incremento de 23,1% a 38,5% na matéria seca de raízes das plantas da cultivar Pérola na presença de AB213 e AB219, respectivamente. A presença de AB213 incrementou em 15,2% a matéria seca da parte aérea das plantas da cultivar Smooth Cayenne. Os resultados revelam a eficiência de bactérias diazotróficas na promoção do crescimento de abacaxizeiros.The objective of this work was to select and to evaluate isolates of diazotrophic bacteria associated to pineapple (Ananas comosus (L. Merril plants in the development of micropropagated plantlets of cultivars pineapple in greenhouse. Plantlets from the Perolera cultivar have been submitted to inoculation with Asaia bogorensis (AB219 and were cultivated during 145 days on the following

  6. Water Efficient Installations - A New Army Guidance Document

    Science.gov (United States)

    2010-06-01

    Detection and Repair 4. Water Efficient Landscaping 5. Water Efficient Irrigation 6. Toilets and Urinals 7. Faucets and Showerheads 8. Boiler/Steam...lose 8760 to 219,000 gal/year Broken flush valve on toilet can lose 40 gal/hour US Army Corps of Engineers® Engineer Research and Development Center...Amendments ( Compost ) 20 Irrigation Scheduling

  7. 48 CFR 719.271-1 - General.

    Science.gov (United States)

    2010-10-01

    ... 719.271-1 Federal Acquisition Regulations System AGENCY FOR INTERNATIONAL DEVELOPMENT SOCIOECONOMIC PROGRAMS SMALL BUSINESS PROGRAMS Policies 719.271-1 General. The purpose of this section is to prescribe responsibilities and procedures for carrying out the small business program policy set forth in 219.270, and...

  8. Canine Autoanticoagulation during Extracorporeal Perfusion.

    Science.gov (United States)

    1979-12-19

    Chronolog, Havertown, PA). Aggregating agents, adenosine diphosphate (ADP) (Si.ma Chemical Co., St. Louis, 14) and topical bovine thrombin (Parke-Davis...time with kaolin ; a simple screening test for first stage plasma clotting factor deficiencies. Amer. J. Clin. Pathol. 36: 212-219, 1961. 35. Quick, A

  9. Internet Integration in High Schools: Patterns, Opportunities, and Barriers.

    Science.gov (United States)

    Thomas, Ruth; Adams, Marilyn; Meghani, Naheed; Smith, Maria

    Internet integration in high schools on a schoolwide scale was examined through case studies of five high schools in inner city, urban, suburban, and rural communities across the United States. A total of 322 teachers, 19 administrators, 19 counselors, 7 technology coordinators, and 3,822 students were surveyed, and 219 staff and students were…

  10. 47 CFR 95.851 - Certification.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Certification. 95.851 Section 95.851 Telecommunication FEDERAL COMMUNICATIONS COMMISSION (CONTINUED) SAFETY AND SPECIAL RADIO SERVICES PERSONAL RADIO SERVICES 218-219 MHz Service Technical Standards § 95.851 Certification. Each CTS and RTU transmitter...

  11. The Effects of Duration and Frequency of Occurrence of Voiceless Fricatives on Listeners' Perceptions of Sound Prolongations

    Science.gov (United States)

    Kawai, Norimune; Healey, E. Charles; Carrell, Thomas D.

    2012-01-01

    The present study examined listeners' identification and rating of words in passages as stuttered when the duration and frequency of occurrence of sound prolongations were manipulated. Thirty-six participants listened to a 219-word passage containing voiceless fricatives digitally increased from their normal durations to 200, 300, and 420 ms.…

  12. Dicty_cDB: CFD757 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available LEa0014A23f, mRNA sequence. 74 6e-12 2 AF333116 |AF333116.1 Sterkiella histriomuscorum turgor-like protein g...56 AY883858_1( AY883858 |pid:none) Sterkiella histriomuscorum turgor ... 219 1e-5

  13. Dicty_cDB: AFJ614 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available A sequence. 42 1e-05 3 BG711333 | ( S74728 ) antiquitin=26g turgor protein homolog [human, kidney, Peptide, ...Sterkiella histriomuscorum turgor ... 219 2e-55 BT067707_1( BT067707 |pid:none) Zea mays full-length cDNA cl

  14. Dicty_cDB: VFI240 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available 3e-05 3 BG711333 | ( S74728 ) antiquitin=26g turgor protein homolog [human, kidney, Peptide, 511 aa] [Homo s...8 |pid:none) Sterkiella histriomuscorum turgor ... 219 1e-55 AY847462_1( AY847462 |pid:none) Acanthopagrus s

  15. Papel de las células NK y linfocitos T en la respuesta inmune frente a Chlamidophyla abortus en modelo murino / Carlos Manuel Martínez Cacéres; directores, Joaquín Sánchez Campillo, Antonio J. Buendía Marín y Jesús Salinas Lorente.

    OpenAIRE

    Martínez Cáceres, Carlos Manuel

    2006-01-01

    Tesis-Universidad de Murcia. Consulte la tesis en: BCA. GENERAL. ARCHIVO UNIVERSITARIO. T.M. 3026. Consulte la tesis en: BCA. GENERAL. Fac. Veterinaria. Departamentos. E002B TESIS 111. Consulte la tesis en: BCA. GENERAL. Fac. Veterinaria. Sala de estudio. Tesis-V 219.

  16. Panorama of PetroChina Oil and Gas Development in 1996~2000

    Institute of Scientific and Technical Information of China (English)

    Jiang Sixiong

    2001-01-01

    @@ As of the end of 2000,PetroChina found 293 oil fields in total across China with the proven oil in place being 14.35 billion tons and the recoverable reserves being 4.38 billion tons. A total of 219 oil fields in its affiliated 13oil areas have been put into development.

  17. Effects of Welfare Participation on Marriage

    Science.gov (United States)

    Teitler, Julien O.; Reichman, Nancy E.; Nepomnyaschy, Lenna; Garfinkel, Irwin

    2009-01-01

    We investigated the widely held premise that welfare participation causes women to refrain from marriage. Using data from the Fragile Families and Child Wellbeing Study (N = 3,219), we employed an event history approach to study transitions to marriage among mothers who have had a nonmarital birth. We found that welfare participation reduces the…

  18. What Teens Want to Know: Sexual Health Questions Submitted to a Teen Web Site

    Science.gov (United States)

    Vickberg, Suzanne M. Johnson; Kohn, Julia E.; Franco, Lydia M.; Criniti, Shannon

    2003-01-01

    In 1999 Planned Parenthood[R] Federation of America (PPFA[R]) launched teenwire.com[SM], a Web site for young people. This study was designed to determine teens' reproductive health information needs. Selected for analysis were 1,219 submissions to the Ask the Experts section of the Web site. Each submission was independently coded by three of the…

  19. New Genome-Wide Algorithm Identifies Novel In-Vivo Expressed Mycobacterium Tuberculosis Antigens Inducing Human T-Cell Responses with Classical and Unconventional Cytokine Profiles

    DEFF Research Database (Denmark)

    Coppola, Mariateresa; van Meijgaarden, Krista E.; Franken, Kees L. M. C.

    2016-01-01

    . By further analysing high-level conservation among whole-genome sequenced Mtb-complex strains (n = 219) and algorithms predicting HLA-class-Ia and II presented epitopes, we selected the most promising IVE-TB candidate antigens. Several of these were recognized by T-cells from in-vitro Mtb-PPD and ESAT6/CFP10...

  20. Reliability and Validity of Autism Diagnostic Interview-Revised, Japanese Version

    Science.gov (United States)

    Tsuchiya, Kenji J.; Matsumoto, Kaori; Yagi, Atsuko; Inada, Naoko; Kuroda, Miho; Inokuchi, Eiko; Koyama, Tomonori; Kamio, Yoko; Tsujii, Masatsugu; Sakai, Saeko; Mohri, Ikuko; Taniike, Masako; Iwanaga, Ryoichiro; Ogasahara, Kei; Miyachi, Taishi; Nakajima, Shunji; Tani, Iori; Ohnishi, Masafumi; Inoue, Masahiko; Nomura, Kazuyo; Hagiwara, Taku; Uchiyama, Tokio; Ichikawa, Hironobu; Kobayashi, Shuji; Miyamoto, Ken; Nakamura, Kazuhiko; Suzuki, Katsuaki; Mori, Norio; Takei, Nori

    2013-01-01

    To examine the inter-rater reliability of Autism Diagnostic Interview-Revised, Japanese Version (ADI-R-JV), the authors recruited 51 individuals aged 3-19 years, interviewed by two independent raters. Subsequently, to assess the discriminant and diagnostic validity of ADI-R-JV, the authors investigated 317 individuals aged 2-19 years, who were…

  1. Main: AMMORESIIUDCRNIA1 [PLACE

    Lifescience Database Archive (English)

    Full Text Available AMMORESIIUDCRNIA1 S000374 31-Jul-2001 (last modified) uchi Motifs (IIU and IID) fou...nd in the Chlamydomonas (C.R.) Nia1 gene promoter; Involved in ammonium-response; Located between -231 and -...219 and also between -76 and -65; Involved in Nia1 transcription activation; W=T/A; nitrate reductase; ammonium response; Chlamydomonas reinhardtii GGWAGGGT ...

  2. Drug: D03537 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D03537 Drug Clevudine (USAN) C10H13FN2O5 260.0809 260.219 D03537.gif Antiviral used in the treatment of hepa...titis B infection ATC code: J05AF12 RNA-directed DNA polymerase inhibitor map07044

  3. 76 FR 58252 - Applications for New Awards; Statewide, Longitudinal Data Systems Program

    Science.gov (United States)

    2011-09-20

    ... primarily responsible for the State supervision of elementary schools and secondary schools. See 20 U.S.C. 9601 (which incorporates by reference the definition of SEA set out in section 9101 of the Elementary... Statistics, 1990 K Street, NW., room 9023, Washington, DC 20006-5651. Telephone: (202) 219-7080 or by...

  4. Palmyra Atoll Site 15P 3/31/2004 68-69M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 68 and 69 meters along a permanent transect.

  5. Risk of cardiovascular disease in family members of young sudden cardiac death victims

    DEFF Research Database (Denmark)

    Ranthe, Mattis Flyvholm; Winkel, Bo Gregers; Andersen, Elisabeth Wreford

    2012-01-01

    ), along with their first- and second-degree relatives (n = 3073). We compared the incidence of CVD in those relatives with that in the background population using standardized incidence ratios (SIRs). The observed number of CVDs over 11 years of follow-up was 292, compared with 219 expected based...

  6. American Public Support for US Military Operations from Mogadishu to Baghdad

    Science.gov (United States)

    2005-01-01

    release, June 23, 2003. ", "Bush Faces Rising Public Doubts on Credibility and Casualties Alike," news release, July 11, 2003. Ajzen , Icek , and Martin...to be amply supported by psychological research on persuasion. See, for example, Petty and Cacioppo (1981, 1986). Ajzen and Fishbein (1980, pp. 219

  7. Extraction of radioactive positive ions across the surface of superfluid helium : A new method to produce cold radioactive nuclear beams

    NARCIS (Netherlands)

    Huang, WX; Dendooven, P; Gloos, K; Takahashi, N; Pekola, JP; Aysto, J

    2003-01-01

    Alpha-decay recoils Rn-219 were stopped in superfluid helium and positive ions were extracted by electric field into the vapour phase. This first quantitative observation of extraction was successfully conducted using highly sensitive radioactivity detection. The efficiency for extraction across the

  8. Production of zero energy radioactive beams through extraction across superfluid helium surface

    NARCIS (Netherlands)

    Takahashi, N; Huang, WX; Gloos, K; Dendooven, P; Pekola, JP; Aysto, J

    2003-01-01

    A radioactive Ra-223 source was immersed in superfluid helium at 1.2-1.7 K. Electric fields transported recoiled Rn-219 ions in the form of snowballs to the surface and further extracted them across the surface. The ions were focussed onto an aluminium foil and alpha particle spectra were taken with

  9. The Effect of Childhood Trauma on Later Psychological Adjustment

    Science.gov (United States)

    Browne, Caroline; Winkelman, Cecelia

    2007-01-01

    This study examined whether adult attachment and cognitive distortion mediate the relationship between childhood trauma and psychological adjustment. The participants were 219 students (40 men and 117 women) enrolled in a university degree. Participants completed the Childhood Trauma Questionnaire, which assessed retrospective accounts of…

  10. A Cross-Cultural Analysis of Interpersonal Needs.

    Science.gov (United States)

    Cambra, Ronald E.; Klopf, Donald W.

    The Fundamental Interpersonal Relations Orientation--Behavior (FIRO-B) was administered to 504 Japanese, 219 Australian, 73 Korean, and 397 United States college students to assess interpersonal needs in the four cultures. The FIRO-B provides ratings for inclusion, control, and affection needs on an "expressed" dimension to indicate the behavior…

  11. Art Makes All Things Better

    Science.gov (United States)

    Eisele, Kimi

    2008-01-01

    Room M219 of Tucson's Catalina High School feels more like a hip design shop or bustling photography studio than an advanced English as a Second Language (ESL) class. Printouts of photographs lie scattered amidst rows of computers. Fingers dash across keyboards and images flash onto monitors as students review their own work. One would never guess…

  12. More Abstracts on Effects of Radiation on Electronic Devices

    Science.gov (United States)

    Bouquet, Frank L.

    1987-01-01

    Second volume of bibliography summarizes literature on radiation effects on new electronic devices. Includes those of protons, electrons, neutrons, gamma rays, and cosmic rays at energies up to about 20 GeV. Volume contains 219 abstracts from unclassified sources. Organized into four sections: dose-rate effects, new technology, post-irradiaton effects, and test environments.

  13. Long-Run Impact of the Thirty Cent Revision in Ontario's Minimum Wage on Five Industries.

    Science.gov (United States)

    McKenna, Ian B.

    To determine the effect of a legislated increase in the minimum wage in Ontario, 219 establishments in five industries were surveyed. The industries were shoe factories; luggage, handbag, and small leather goods manufacturers; hosiery mills, children's clothing industry; and the foundation garment industry. Data were gathered at three different…

  14. Drinking and Dating: Examining the Link among Relationship Satisfaction, Hazardous Drinking, and Readiness-to-Change in College Dating Relationships

    Science.gov (United States)

    Khaddouma, Alexander; Shorey, Ryan C.; Brasfield, Hope; Febres, Jeniimarie; Zapor, Heather; Elmquist, Joanna; Stuart, Gregory L.

    2016-01-01

    For this study we examined the association between relationship satisfaction and readiness-to-change alcohol use, as well as the associations between hazardous drinking and readiness-to-change relationship issues in college dating relationships. A sample of 219 college students in a current dating relationship (aged 18-25) completed self-report…

  15. 36 CFR 251.9 - Management of Municipal Watersheds.

    Science.gov (United States)

    2010-07-01

    ... multiple use prescriptions in forest plans (36 CFR part 219). When a municipality desires protective... authorizations, the municipality must apply to the Forest Service for consideration of these needs. (b) When... incorporated in the forest plan without written agreements. Written agreements with municipalities to...

  16. 77 FR 76898 - Freedom of Information Act Regulations

    Science.gov (United States)

    2012-12-31

    ... while more complex requests are processed. To clarify this point, the Department has added paragraph (f... the basic time limit (Sec. 2.19) and a cross reference to it has been added to Sec. 2.16(a). The... analysis and will be subject late to the NEPA process, either collectively or case-by- case.'' 10....

  17. 48 CFR 207.172 - Human research.

    Science.gov (United States)

    2010-10-01

    ... compliance with 32 CFR Part 219, Protection of Human Subjects; and (b) Must have a Human Research Protection... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Human research. 207.172... OF DEFENSE ACQUISITION PLANNING ACQUISITION PLANNING Acquisition Plans 207.172 Human research. Any...

  18. Palmyra Atoll Site 15P 3/31/2004 30-31M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 30 and 31 meters along a permanent transect.

  19. Feeding fat from distillers dried grains with solubles to dairy heifers: III. Effects on long-term reproductive and lactation performance

    Science.gov (United States)

    During the prepubertal growth phase, 33 Holstein heifers (133 ± 18 d old) were used in a 24-week randomized complete block design. Treatments included: 1) a control diet (CON) containing ground corn (15.9% of DM) and soybean products (17.9%); 2) a low-fat diet (LFDG) formulated with 21.9% fat-extrac...

  20. Odontocete Movements off the Island of Kauai: Results of Satellite Tagging and Photo-Identification Efforts in January 2012

    Science.gov (United States)

    2012-08-27

    structure of island-associated dolphins: evidence from mitochondrial and microsatellite markers for common bottlenose dolphins (Tursiops truncatus... malfunction . The Pacific Missile Range Facility (PMRF) boundary is shown. 7    21.8 21.9 22 22.1 22.2 -160 -159.9 -159.8 -159.7 -159.6 -159.5 La tit

  1. Palmyra Atoll Site 15P 3/31/2004 64-65M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 64 and 65 meters along a permanent transect.

  2. Photoacoustic Imaging of Epilepsy

    Science.gov (United States)

    2014-04-01

    formulae for the spherical mean radon transform,” Inverse Probl. 23(1), 373–383 (2007). 5. D. Finch, S. Patch, and Rakesh, “Determining a Function from...Vickrey, B.G., 2007. Stopping antiepileptic drugs after epilepsy surgery: a survey of U.S. epilepsy center neurologists. Epilepsy Behav. 10, 219– 222

  3. Domain Modeling: NP_787125.1 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_787125.1 chr13 Crystal Structure of Human Fibroblast Growth Factor Homologous Fa...ctor 2A (FHF2A), also referred to as Fibroblast Growth Factor 13A (FGF13A) p3hbwb_ chr13/NP_787125.1/NP_787125.1_apo_71-219.pdb blast 0 ...

  4. Studies on ageing and the severity of radiographic joint damage in rheumatoid arthritis

    NARCIS (Netherlands)

    Mangnus, Lukas; van Steenbergen, Hanna W.; Lindqvist, Elisabet; Brouwer, Elisabeth; Reijnierse, Monique; Huizinga, Tom W. J.; Gregersen, Peter K.; Berglin, Ewa; Rantapaa-Dahlqvist, Solbritt; van der Heijde, Desiree; van der Helm-van Mil, Annette H. M.

    2015-01-01

    Introduction: The western population is ageing. It is unknown whether age at diagnosis affects the severity of Rheumatoid Arthritis (RA), we therefore performed the present study. Method: 1,875 RA-patients (7,219 radiographs) included in five European and North-American cohorts (Leiden-EAC, Wichita,

  5. Pre-adolescent gender differences in associations between temperament, coping and mood

    NARCIS (Netherlands)

    G.M. de Boo; M. Spiering

    2010-01-01

    Relationships between temperament, coping, depressive and aggressive mood in 8-12-year-old boys (n = 185) and girls (n = 219) were investigated, with a focus on gender differences. Children completed two self-report questionnaires: the Early Adolescent Temperament Questionnaire-Revised and Children'

  6. 75 FR 69662 - Public Water System Supervision Program Revision for the State of Colorado

    Science.gov (United States)

    2010-11-15

    ... [Federal Register Volume 75, Number 219 (Monday, November 15, 2010)] [Notices] [Page 69662] [FR Doc No: 2010-28497] ENVIRONMENTAL PROTECTION AGENCY [FRL-9225-3] Public Water System Supervision... Public Water System Supervision (PWSS) Primacy Program by adopting Federal regulations for the Lead...

  7. Survey of the Indications for Use of Emergency Tourniquets

    Science.gov (United States)

    2011-01-01

    of Trauma; 54(5 Suppl):S219-S220. 3. Husum H, Ang SC, Fosse E (1995). War Sur- gery Field Manual. Penang , Malaysia, Third World Network, 85: 145...are developed (Table 7). CONCLUSION Indications for emergency tourniquet use are complex and have been rarely evidenced so these findings fill

  8. Characteristics of Absenteeism in Nursing Home Staff.

    Science.gov (United States)

    Cohen-Mansfield, Jiska; Rosenthal, Alvin S.

    This study investigated factors associated with absenteeism among nursing staff (N=219) at a long-term care facility. Four absenteeism measures were calculated from personnel records for each month of the year: no pay (the sum of unscheduled, unpaid sick, and leave without pay), part day (the sum of arrived late and left early), paid sick, and…

  9. Circumstances Surrounding Male Sexual Assault and Rape: Findings from the National Violence against Women Survey

    Science.gov (United States)

    Light, David; Monk-Turner, Elizabeth

    2009-01-01

    Much work in the area of male sexual assault and rape relies on small clinical samples. From these samples, researchers reported that most male victims were physically injured during the attack and that penetration occurred. This work rests on a subsample of 219 men from the 1994-1996 Violence and Threats of Violence Against Women and Men in the…

  10. AcEST: DK953538 [AcEST

    Lifescience Database Archive (English)

    Full Text Available FVHVLRERHEV 219 >sp|Q6P7K0|CMBL_XENTR Carboxymethylenebutenolidase homolog OS=Xenopus tropicalis GN=cmbl PE=...84 LEQVSLLEEKLKVHSKVDFQVKVFP 208 >sp|Q5XH09|CMBL_XENLA Carboxymethylenebutenolidase homolog OS=Xenopus laevis GN=cmb

  11. Couples at risk following the death of their child : predictors of grief versus depression

    NARCIS (Netherlands)

    Wijngaards-de Meij, Leoniek; Stroebe, Margaret; Schut, Henk; Stroebe, Wolfgang; van den Bout, Jan; van der Heijden, Peter; Dijkstra, Iris

    2005-01-01

    This longitudinal study examined the relative impact of major variables for predicting adjustment (in terms of both grief and depression) among bereaved parents following the death of their child. Couples (N = 219) participated 6, 13, and 20 months postloss. Use of multilevel regression analyses ena

  12. 75 FR 28849 - Review of the Designation of Ansar al-Islam (aka Ansar Al-Sunnah and Other Aliases) as a Foreign...

    Science.gov (United States)

    2010-05-24

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Review of the Designation of Ansar al-Islam (aka Ansar Al-Sunnah and Other Aliases) as a Foreign Terrorist Organization Pursuant to Section 219 of the Immigration and Nationality Act, as Amended Based upon a review...

  13. The results of CO2 laser surgery in patients with oral leukoplakia : a 25 year follow

    NARCIS (Netherlands)

    van der Hem, PS; Nauta, JM; van der Wal, JE; Roodenburg, JLN

    2005-01-01

    Oral leukoplakia, is an important premalignant Lesion of the oral mucosa. We treat this Lesion prophylactically with CO2 laser evaporation. In the period from 1976 to 2001, a group of 200 patients with 282 oral leukoplakias were treated by CO2 laser evaporation. In a follow up period of 1-219 months

  14. The "Small Change" of Soldiering? Peace Operations as Preparation for Future Wars

    Science.gov (United States)

    1998-06-05

    the 112 Raymond Aron, Main Currents in Sociological Thought 2: Pareto, Weber, Durkheim (Middlesex, U.K.: Penguin Books, 1967), 219, 247-48; Max...Great War. West Point, NY: United States Military Academy, 1977. Aron, Raymond. Main Currents in Sociological Thought 2: Pareto, Weber, Durkheim

  15. Examining the Effect of Computer-Based Passage Presentation on Reading Test Performance

    Science.gov (United States)

    Higgins, Jennifer; Russell, Michael; Hoffmann, Thomas

    2005-01-01

    To examine the impact of transitioning 4th grade reading comprehension assessments to the computer, 219 fourth graders were randomly assigned to take a one-hour reading comprehension assessment on paper, on a computer using scrolling text to navigate through passages, or on a computer using paging text to navigate through passages. This study…

  16. Chemistry and Physics of Weakly Ionized Plasmas

    Science.gov (United States)

    2010-01-22

    constants k(E,J) for the dissociation of molecular ions J. Troe, V. G. Ushakov, and A. A. Viggiano Zeitschrift für Physikalische Chemie 219, 715-741 (May...energy distributions in the dissociation of n-propylbenzene cations (invited) J. Troe, V. G. Ushakov, and A. A. Viggiano Zeitschrift für Physikalische

  17. 47 CFR 95.859 - Antennas.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 5 2010-10-01 2010-10-01 false Antennas. 95.859 Section 95.859... SERVICES 218-219 MHz Service Technical Standards § 95.859 Antennas. (a) The overall height from ground to topmost tip of the CTS antenna shall not exceed the height necessary to assure adequate service....

  18. ADDRESSING THE DEFICIT: Updating the Budgetary Implications of Selected GAO Work

    Science.gov (United States)

    1996-06-01

    Insurance Policies and 219 Deferred Annuities Federal Agency Reporting to the Internal Revenue Service 221 Independent Contractor Tax Compliance 222...Federal agency reporting to the Internal Revenue Service Receipts Direct Improve efficiency Independent contractor tax compliance Receipts Direct Improve...annuities Federal agency reporting to the Internal Revenue Service Independent contractor tax compliance Deductibility of home equity loan interest

  19. The Passive, Ground-Based, Electro-Optical Detection of Synchronous Satellites

    Science.gov (United States)

    1978-06-19

    Lincoln Laboratory, M.I.T. (16 August 1974), DDC AD-785137/1. 47 12. V. J. Santilli and G. B. Conger III, Adv. Electron. Electron Phys. 33A, 219...Air Force Systems Command, USAF Andrews AFB Washington, DC 20331 12. REPORT DATE 19 June 1978 13. NUMBER OF PAGES 54 14. MONITORING

  20. The Efficacy of an Aquatic Program on Physical Fitness and Aquatic Skills in Children with and without Autism Spectrum Disorders

    Science.gov (United States)

    Pan, Chien-Yu

    2011-01-01

    This study evaluated the efficacy of a 14-week aquatic program on physical fitness and aquatic skills for children with autism spectrum disorders (ASD) and their siblings without a disability. Children with ASD (n = 15) and their siblings (n = 15), between 7 and 12 years (8.55 [plus or minus] 2.19 years) participated. In the first 14-week phase,…

  1. 75 FR 504 - In the Matter of the Review of the Designation of Kahane Chai (aka American Friends of the United...

    Science.gov (United States)

    2010-01-05

    ... Matter of the Review of the Designation of Kahane Chai (aka American Friends of the United Yeshiva... Judea Police aka Judean Congress aka Kach aka Kahane aka Kahane Lives aka Kahane Tzadak aka Kahane.org... to Section 219 of the Immigration and Nationality Act, as amended Based upon a review of...

  2. Biological Defense Research Program

    Science.gov (United States)

    1989-04-01

    the data of Babudieri and Moscovici (54), C. burnetii is relatively resistant to ultraviolet rays; however, Siegert et al. (55) showed a marked...four viruses. J. Hyg., Camb. 59:479-484. 54. Babudieri, B., and Moscovici , C. 1952. Bandie Inst. Super. San. 15:215-219. 55. Siegert, R., Peter, H

  3. Domain Modeling: NP_001561.3 [SAHG[Archive

    Lifescience Database Archive (English)

    Full Text Available NP_001561.3 chr3 Structural Basis for the Interaction of TAK1 Kinase with its Activ...ating Protein TAB1 p2evaa_ chr3/NP_001561.3/NP_001561.3_holo_194-543.pdb psi-blast 216I,217S,218Q,219G,224V,

  4. A Practical Approximation Algorithm for the LTS Estimator

    Science.gov (United States)

    2015-07-02

    of Recent Robust Methods, Statistics for Industry and Technology, Birkhäuser, Basel , 2004, pp. 207–219. [7] D. M. Mount, N. S. Netanyahu, K. R...Fig. B.21(a)) ( iii ) [Exiting an interval?] Otherwise, bk is the right endpoint of some interval of B. Set sum← sum + bk and ssq← ssq + (bk)2 (see Fig

  5. 48 CFR 1519.203 - Mentor-protege.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Mentor-protege. 1519.203... PROGRAMS SMALL BUSINESS PROGRAMS Policies 1519.203 Mentor-protege. (a) The Contracting officer shall insert the clause at 1552.219-70, Mentor-Protege Program, in all contracts under which the Contractor...

  6. Baltisakslaste kunstivaramud Poznani Rahvusmuuseumis : peatükk ühe rahvusgrupi ajaloost / Anne Lõugas

    Index Scriptorium Estoniae

    Lõugas, Anne, 1951-

    1998-01-01

    Eestiga seotud vanema kunsti kogu on kujunenud välja eri ajaetappidel ja eri allikatest. Käsitletakse 1939-1944 Eestist väljaviidud kunstiteoseid, kirjandust baltisakslaste ümberasumisest. Poznani Rahvusmuuseumis asuvate Eestiga seotud baltisaksa maalide nimekiri lk. 205-219

  7. AcEST: BP920406 [AcEST

    Lifescience Database Archive (English)

    Full Text Available ng pro... 32 2.4 sp|Q55274|ISIA_SYNY3 Iron stress-induced chlorophyll-binding pro... 31 4.1 sp|Q62ZD8|VGB_BACLD Virginiamycin... 208 LYHLTVPPLHWMKTSKSFSGHAIIA 282 ++H+ VPPL W K FSG AI++ Sbjct: 219 IWHILVPPLGWAKKVLLFSGEAILS 243 >sp|Q62ZD8|VGB_BACLD Virginiamycin

  8. Drug: D04285 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D04285 Mixture, Drug Concentrated glycerin - fructose mixt; Glyceol (TN) Concentrated...organs 131 Ophthalmic agents 1319 Others D04285 Concentrated glycerin - fructose ...mixt 2 Agents affecting individual organs 21 Cardiovascular agents 219 Miscellaneous 2190 Miscellaneous D04285 Concentrated...399 Miscellaneous 3999 Others D04285 Concentrated glycerin - fructose mixt PubChem: 17398044 ...

  9. Models in Insurance: Paradigms, Puzzles, Communications and Revolutions.

    Science.gov (United States)

    1980-06-01

    Models in Light of Futurism," 229-242. [80.22] A. Martinez, "Interpretaci6n del Fen6mino Actuarial mediante un Proceso Estocastico Evolutivo de Variables... Teoria della Credibilit&," Giornale dell’ Istituto degli Attuari, 27, 219-231 (1964). (D51 N. De Pril, "The Efficiency of a Bonus-Malus System," AB, 10

  10. Geochemistry of ferromanganese micronodules and associated Mn and trace metals diagenesis at high terrigenous depositional site of middle fan region, Bay of Bengal

    Digital Repository Service at National Institute of Oceanography (India)

    Chauhan, O.S.

    The influence of sedimentation on the morphology, growth and geochemistry of the micronodules, and on Mn enrichment in the sediments of the Bay of Bengal has been evaluated. Mn accumulation is 307-219 mg cm u2 kyr u-1 in cores having 20-17 cm kyr u...

  11. Flow-induced vibration of circular cylindrical structures

    Energy Technology Data Exchange (ETDEWEB)

    Chen, S.S.

    1985-06-01

    This report summarizes the flow-induced vibration of circular cylinders in quiescent fluid, axial flow, and crossflow, and applications of the analytical methods and experimental data in design evaluation of various system components consisting of circular cylinders. 219 figs., 30 tabs. (JDB)

  12. Palmyra Atoll Site 15P 3/31/2004 101-102M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 101 and 102 meters along a permanent transect.

  13. Development of a Vision-Based Particle Tracking Velocimetry Method and Post-Processing of Scattered Velocity Data

    Science.gov (United States)

    2012-01-01

    geostatistics (Journel and Huijbregts, 1978). We can arrive at another method for deriving differential quantities by manipulating a technique...2): 219-231. 27. Journel A, Huijbregts CH. (1978) Mining Geostatistics . Academic Press Inc. (London) LTD. 28. Keane R, Adrian R. (1995). Super

  14. A Laser Feedback Control Design for Passive Ring Laser Gyros in a Very High Finesse Cavity.

    Science.gov (United States)

    1985-12-01

    14 II. Theory ....................... 16 Optical Cavities ................ 16 Laser Fundamentals ...............24 The Gaussian Beam. ...............28...c 1-(ABC 1h(.8 = (2.18) F = 1 2.19) - (RARCRD) t = = (2.20) C c[i- (RARRc%)] Laser Fundamentals A laser consists of three basic components: a gain

  15. AcEST: DK948146 [AcEST

    Lifescience Database Archive (English)

    Full Text Available ne and TPR repeat-containing pr... 30 8.2 sp|A2R3F3|SHE9_ASPNC Sensitive to high expression protein 9 homo.....QLQPEQGAAYVTYGQTLARNGS 710 Query: 221 R 219 R Sbjct: 711 R 711 >sp|A2R3F3|SHE9_ASPNC Sensitive

  16. Mutations in X-linked PORCN, a putative regulator of Wnt signaling, cause focal dermal hypoplasia

    Science.gov (United States)

    Focal dermal hypoplasia is an X-linked dominant disorder characterized by patchy hypoplastic skin and digital, ocular, and dental malformations. We used array comparative genomic hybridization to identify a 219-kb deletion in Xp11.23 in two affected females. We sequenced genes in this region and fou...

  17. Gclust Server: 9975 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 9975 Bja_bll4497=nthB Cluster Sequences - 219 nitrile hydratase subunit beta 11 1.0...0e-50 0.0 0.0 0.0 33.33 16.13 0.0 Show 9975 Cluster ID 9975 Sequence ID Bja_bll4497=nthB Link to cluster seq

  18. The Genetic and Environmental Covariation among Psychopathic Personality Traits, and Reactive and Proactive Aggression in Childhood

    Science.gov (United States)

    Bezdjian, Serena; Tuvblad, Catherine; Raine, Adrian; Baker, Laura A.

    2011-01-01

    The present study investigated the genetic and environmental covariance between psychopathic personality traits with reactive and proactive aggression in 9- to 10-year-old twins (N = 1,219). Psychopathic personality traits were assessed with the Child Psychopathy Scale (D. R. Lynam, 1997), while aggressive behaviors were assessed using the…

  19. 78 FR 61866 - Sport Fishing and Boating Partnership Council

    Science.gov (United States)

    2013-10-04

    ...'' under SUPPLEMENTARY INFORMATION. ADDRESSES: The meeting will be held at the Omni Royal Orleans Hotel...] [FR Doc No: 2013-24314] DEPARTMENT OF THE INTERIOR Fish and Wildlife Service [FWS-HQ-EA-2013-N219... Service, Interior. ACTION: Notice of meeting. SUMMARY: We, the U.S. Fish and Wildlife Service...

  20. 77 FR 31347 - Tennessee Gas Pipeline Company, L.L.C.; Notice of Availability of the Environmental Assessment...

    Science.gov (United States)

    2012-05-25

    ... markets in Ohio and Tennessee. \\1\\ A pipeline loop is a segment of pipe constructed parallel to an... stations to provide bi-directional natural gas flow: Station 219 in Mercer County, Station 303 in Venango... encourages electronic filing of comments and has expert staff available to assist you at (202) 502-8258...

  1. 49 CFR 175.10 - Exceptions for passengers, crewmembers, and air operators.

    Science.gov (United States)

    2010-10-01

    .... This paragraph does not apply to persons traveling under the provisions of 49 CFR 1544.219. (9) One... representative of a government weather bureau or similar official agency, provided that individual advises the... crewmember, including transfer to another carrier for transport to its final destination. (c)...

  2. Merula Javanica (Horse.) and M. fumida (S. Müll.) two distinct species

    NARCIS (Netherlands)

    Finsch, O.

    1899-01-01

    Seeb. Cat. Br. M. V, 1881, p. 279 (part. only spec. a, b, c Types). id. Ibis 1893, p. 219 (Note). Owing to the incorrect diagnosis given by Horsfield 1) of his » Tardus javanicus it would be impossible to refer on this species at all, if not, fortunately, the types were preserved in the Collection o

  3. Miscellaneous disorders

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    930192 Influence of corticosteroid on IgG in-dex and IgG synthesis rate in multiple sclerosis.LU Ming(刘鸣),et al.Dept Neurol,lst AffiliHosp,West—China Med Univ,Chengdu,610041.Chin J Nerv and Med Dis 1992;18(4):219—220.China Medical Abstracts(Internal Medicine)

  4. Resources for Increasing Physical Activity in Children and Youth

    Science.gov (United States)

    Ryan, Carol A.; Beighle, Aaron

    2010-01-01

    The number of children and youth who are overweight has reached epidemic proportions in the United States. According to the 2007-2008 National Health and Nutrition Examination Survey (NHANES) conducted by the Centers for Disease Control and Prevention (CDC), an estimated 17 percent of children and adolescents ages 2-19 years are obese. In…

  5. Community Education in Canada. An Annotated Bibliography. OISE Bibliography Series No. 2.

    Science.gov (United States)

    Corman, Linda, Comp.

    This bibliography of 219 numbered entries is limited to Canadian works. However, section 4, "Bibliographies," will provide leads to useful information from the United States. Section 1, "Community Schools/Community Education," includes the more comprehensive works and material about particular Canadian community schools,…

  6. Palmyra Atoll Site 15P 3/31/2004 31-32M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 31 and 32 meters along a permanent transect.

  7. Palmyra Atoll Site 15P 3/31/2004 87-88M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 87 and 88 meters along a permanent transect.

  8. The Relationship between Sensation-Seeking and Eysenck's Dimensions of Personality.

    Science.gov (United States)

    Eysenck, Sybil; Zuckerman, Marvin

    1978-01-01

    The Eysenck Personality Questionnaire (EPQ) and the Sensation-Seeking Scale were administered to 219 American undergraduates and 879 English twins. Sensation-seeking was positively correlated to EPQ-measured traits of extraversion and psychoticism. There was no relationship between sensation-seeking and the trait dimension of neuroticism.…

  9. Investigation of a gas-catcher/ion guide system using alpha-decay recoil products

    Energy Technology Data Exchange (ETDEWEB)

    Peraejaervi, K. E-mail: kari.perajarvi@phys.jyu.fi; Huikari, J.; Rinta-Antila, S.; Dendooven, P

    2002-04-22

    {sup 219}Rn recoils from the alpha decay of {sup 223}Ra have been used to study the efficiency and delay time distributions of a gas-catcher/ion guide system. Ions with charge states up to +4 were coming out of the gas cell. Combining efficiency and delay time measurements, ion survival times in plasma free conditions can be deduced.

  10. 78 FR 23491 - National Forest System Land Management Planning; Correction

    Science.gov (United States)

    2013-04-19

    ... Forest Service 36 CFR Part 219 RIN 0596-AB86 National Forest System Land Management Planning; Correction...-1104. FOR FURTHER INFORMATION CONTACT: Ecosystem Management Coordination staff's Planning Specialist... management plans (the planning rule). The National Forest Management Act (NFMA) at 16 U.S.C....

  11. Bibliography of Scientific Publications 1977-1991.

    Science.gov (United States)

    1992-06-01

    34 Personality and Individual Differences in Human Performance Newsletter, Vol. 1, No. 1, unpaged, March 1988. Gibb, G.D., Nontasak, T.N., and Dolgin...Pensacola, FL, December 1988. (AD A219 600) Severin, K.H., ’Personality, Individual Differences and Pilot Selection." Personality and Individual Differences in

  12. Bibliography of Scientific Publications 1978-1990,

    Science.gov (United States)

    1991-09-01

    Automated Selection System for Navy Pilots." Personality and Individual Differences in Human Perfornance Newsletter, Vol. 1, No. 1, unpaged, March 1988...1988. (AD A219 600) Severin, K.H., "Personality, Individual Differences and Pilot Selection." Personality and Individual Differences in Human Performance

  13. The Self-Esteem of Adolescents in American Public High Schools: A Multilevel Analysis of Individual Differences.

    Science.gov (United States)

    Bekhuis, Tanja C. H. M.

    1994-01-01

    A total of 219 schools and 13,022 students from a database of secondary schools and students in the United States were sampled. Analysis of the data revealed that school social climate and several student characteristics predicted student self-esteem and that variability of student self-esteem was greater in southern than northern schools. (BC)

  14. Palmyra Atoll Site 15P 8/11/2006 30-31M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 30 and 31 meters along a permanent transect.

  15. Religion and Pet Loss: Afterlife Beliefs, Religious Coping, Prayer and Their Associations with Sorrow

    Science.gov (United States)

    Lee, Sherman A.

    2016-01-01

    This study examined the relationship between religion and sorrow among a sample of 219 owners of deceased pets (the sample was predominantly comprised of white, female, educated Christians). The results indicated that the vast majority of the participants believed that their pets' souls reside in a better place and that they will reunite with them…

  16. Real world thirty-day mortality in female patients with acute myocardial infarction from Beijing

    Institute of Scientific and Technical Information of China (English)

    宋雷

    2013-01-01

    Objective To evaluate the gender differences on the short-term outcomes of patients with acute myocardial in-farction in the real world.Methods A total of 471 consecutive patients[male 368 (78.1%) and female103 (21.9%) ]with acute myocardial infarction<72 hours in cardiac care unit were included.The clinical data,

  17. Sex Differences in the Sleep EEG of Young Adults : Visual Scoring and Spectral Analysis

    NARCIS (Netherlands)

    Dijk, Derk Jan; Beersma, Domien G.M.; Bloem, Gerda M.

    1989-01-01

    Baseline sleep of 13 men (mean age of 23.5 years) and 15 women (21.9 years) was analyzed. Visual scoring of the electroencephalograms (EEGs) revealed no significant differences between the sexes in the amounts of slow-wave sleep and rapid-eye-movement (REM) sleep. Spectral analysis, however, detecte

  18. Comparative analysis of genome-wide divergence, domestication footprints and genome-wide association study of root traits for Gossypium hirsutum and Gossypium barbadense

    Science.gov (United States)

    Use of 10,129 singleton SNPs of known genomic location in tetraploid cotton provided unique opportunities to characterize genome-wide diversity among 440 Gossypium hirsutum and 219 G. barbadense cultivars and landrace accessions of widespread origin. Using genome-wide distributed SNPs, we examined ...

  19. Genome-wide divergence, haplotype distribution and population demographic histories for Gossypium hirsutum and Gossypium barbadense as revealed by genome-anchored SNPs

    Science.gov (United States)

    Use of 10,129 singleton SNPs of known genomic location in tetraploid cotton provided unique opportunities to characterize genome-wide diversity among 440 Gossypium hirsutum and 219 G. barbadense cultivars and landrace accessions of widespread origin. Using the SNPs distributed genome-wide, we exami...

  20. Dicty_cDB: Contig-U14116-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available rtii subsp. stewartii... 219 2e-55 AB010049_1( AB010049 |pid:none) Schizosaccharomy...3 1e-59 AM743169_795( AM743169 |pid:none) Stenotrophomonas maltophilia K27... 233 1e-59 AY851371_1( AY851371 |pid:none) Pantoea stewa

  1. Family Engagement in Literacy Activities: Revised Factor Structure for the Familia--An Instrument Examining Family Support for Early Literacy Development

    Science.gov (United States)

    Buhs, Eric S.; Welch, Greg; Burt, Jennifer; Knoche, Lisa

    2011-01-01

    This study evaluated a data-set drawn using "The Familia"--a measure originally developed to evaluate shared-reading activities. A newly developed set of conceptual supports and a confirmatory factor analysis (CFA) were applied to a new factor structure/model. Data were drawn from 219 young children and their families (mean age = 43 months)…

  2. Effect of paracentesis on metabolic activity in patients with advanced cirrhosis and ascites

    DEFF Research Database (Denmark)

    Knudsen, Anne Wilkens; Krag, Aleksander; Nordgaard-Lassen, Inge

    2016-01-01

    by -379 (-1915 - 219) kJ/day, (p  = 0.06). Patients in whom measured REE decreased after paracentesis had higher middle arterial pressure (MAP) (p = 0.02) and p-sodium (p = 0.02) at baseline. Low HGS (M: osteoporosis...

  3. AcEST: DK947237 [AcEST

    Lifescience Database Archive (English)

    Full Text Available it) - E-value - Report BLASTX 2.2.19 [Nov-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejan...2.19 [Nov-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang,

  4. AcEST: BP920082 [AcEST

    Lifescience Database Archive (English)

    Full Text Available .2.19 [Nov-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang,... - Definition - Align length - Score (bit) - E-value - Report BLASTX 2.2.19 [Nov-02-2008] Reference: Altschul, Stephen

  5. AcEST: DK947284 [AcEST

    Lifescience Database Archive (English)

    Full Text Available bit) - E-value - Report BLASTX 2.2.19 [Nov-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Aleja....2.19 [Nov-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang,

  6. AcEST: DK946508 [AcEST

    Lifescience Database Archive (English)

    Full Text Available it) - E-value - Report BLASTX 2.2.19 [Nov-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejan...2.19 [Nov-02-2008] Reference: Altschul, Stephen F., Thomas L. Madden, Alejandro A. Schaffer, Jinghui Zhang,

  7. PENGARUH INFUS BUAH Foeniculum vulgare Mill PADA SIKLUS ESTRUS DAN BOBOT UTERUS TIKUS PUTIH

    Directory of Open Access Journals (Sweden)

    Sa'roni Sa'roni

    2012-10-01

    Full Text Available Buah Foeniculum vulgare Mill (adas secara tradisional untuk obat dan campuran jamu pengatur haid. Diduga buah Foeniculum vulgare Mill mempunyai pengaruh pada sistem reproduksi. Oleh karena itu, kami melakukan penelitian pengaruh infus buah Foeniculum vulgare Mill pada siklus estrus dan bobot uterus tikus putih.Infus diberikan secara oral sekali sehari selama 12 hari dengan dosis setara dengan 7,3 mg, 73 mg dan 219 mg/100 g bobot badan. Selama pemberian bahan, siklus estrus diperiksa setiap hari dan pada hari ke-13 diotopsi dan ditimbang bobot uterusnya.Hasil penelitian menunjukkan bahwa infus buah Foeniculum vulgare Mill setara dengan serbuk 7,3 mg, 73 mg dan 219 mg/100 g bobot badan dapat menghambat fase estrus (masa subur. Infus setara dengan serbuk 7 mg dan 219 mg/100 g bobot badan kelihatan dapat menghambat fase estrus yang sangat nyata dibandingkan dengan akuades. Infus buah Foeniculum vulgare Mill setara dengan serbuk 219 mg/100 g bobot badan dapat menurunkan bobot uterus, tetapi secara statistik tidak berbeda nyata dengan akuades. Kata kunci: Obat tradisional; Foeniculum vulgare Mill; Sistem Reproduksi

  8. 78 FR 26069 - Top RX Pharmacy; Decision and Order

    Science.gov (United States)

    2013-05-03

    ... Enforcement Administration Top RX Pharmacy; Decision and Order On November 8, 2012, Chief Administrative Law... ALJ's reasoning suggests that ``inaction'' on the part of a pharmacy's principals in dispensing.../Pharmacy Nos. 219 and 5195, 77 FR 62316, 62317-22 (2012). Order Pursuant to the authority vested in me...

  9. Data of evolutionary structure change: 1ALCA-1LMAA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ALCA-1LMAA 1ALC 1LMA A A KQFTKCELSQNL--YDIDGYGRIALPELICTMFHTSGYD...yChain> 1LMA A 1LMA...55 ASP CA 290 1LMA A 1LMA...U CA 249 GLU CA 193 GLN CA 219 TRP CA 312 1LMA... A 1LMAA NRCKGT

  10. Yeast cell wall supplementation alters the metabolic responses of crossbred heifers to an endotoxin challenge

    Science.gov (United States)

    This study examined the effect of feeding yeast cell wall (YCW) products on the metabolic responses of newly-received heifers to endotoxin challenge. Heifers (n = 24; 219 ± 2.4 kg) were separated into treatment groups receiving a Control diet (n = 8), YCW-A (2.5 grams/heifer/d; n = 8) or YCW-C (2.5 ...

  11. Yeast cell wall supplementation alters the physiological and acute phase responses of crossbred heifers to an endotoxin challenge

    Science.gov (United States)

    A study was conducted to determine the effect of feeding yeast cell wall (YCW) products on the physiological and acute phase responses of crossbred newly-received heifers to an endotoxin challenge. Heifers (n = 24; 219 ± 2.4 kg) were separated into treatment groups receiving a Control diet (n = 8), ...

  12. [Christofer Herrmann. Kloster und Burg - die architektur des Deutschens Ordens im Pressen und Livland. In : Glaube, Macht und Pracht. GeistlicheGemeinschaften des Ostseeraums im Zeitalter der Backsteingotik] / Dennis Hortmuth

    Index Scriptorium Estoniae

    Hortmuth, Dennis

    2011-01-01

    Arvustus: Christofer Herrmann. Kloster und Burg - die Architektur des Deutschen Ordens in Preussen und Livland. In : Glaube, Macht und Pracht. GeistlicheGemeinschaften des Ostseeraums im Zeitalter der Backsteingotik (=Archäologie und Geschichte im Ostseeraum; Archaeology and History of the Baltic 6) Rahden : Verlag Marie Leidorf, 2009. S. 209-219. Saksa Ordu arhitektuurist Preisi- ja Liivimaal

  13. Longitudinal Stability of the Leadership Scale for Sports

    Science.gov (United States)

    Fletcher, Richard B.; Roberts, Margaret H.

    2013-01-01

    This study evaluated the invariance properties of the Leadership Scale for Sport in a sample of 219 female netball players over four time points within a 10-week playing season. Support was found for Chelladurai and Saleh's (1980) hypothesized 5-factor structure of the Leadership Scale for Sport. Furthermore, differential stability and partial…

  14. 78 FR 17744 - In the Matter of the Designation of Ansar al-Dine Also Known as Ansar Dine Also Known as Ansar al...

    Science.gov (United States)

    2013-03-22

    ... Matter of the Designation of Ansar al-Dine Also Known as Ansar Dine Also Known as Ansar al-Din Also Known as Ancar Dine Also Known as Ansar ul-Din Also Known as Ansar Eddine Also Known as Defenders of the Faith as a Foreign Terrorist Organization Pursuant to Section 219 of the Immigration and Nationality...

  15. Performance of 3 Rapid Tests for Discrimination Between HIV-1 and HIV-2 in Guinea-Bissau, West Africa

    DEFF Research Database (Denmark)

    Hønge, Bo Langhoff; Bjarnason Obinah, Magnús Pétur; Jespersen, Sanne;

    2014-01-01

    rapid tests for discrimination between HIV-1, HIV-2, and dual infections among 219 patients from Guinea-Bissau by comparing with the gold standard (INNO-LIA). Genie III HIV-1/HIV-2 was the best performer with regard to discriminatory capacity (agreement 91.8%), followed by Immunoflow HIV1-HIV2...

  16. 78 FR 59708 - Prospective Grant of Exclusive Commercialization License: The Use of Cysteamine for the Treatment...

    Science.gov (United States)

    2013-09-27

    ... the inventions embodied in technology family E-219-2013/0, including U.S. patent application 61/ 814... these technology families, to Raptor Pharmaceuticals, Inc. The patent rights in these inventions have... received by the NIH Office of Technology Transfer on or before October 28, 2013 will be...

  17. Data of evolutionary structure change: 1ALCA-1VEDA [Confc[Archive

    Lifescience Database Archive (English)

    Full Text Available 1ALCA-1VEDA 1ALC 1VED A A KQFTKCELSQNL--YDIDGYGRIALPELICTMFHTSGYD...CA 233 THR CA 295 GLU CA 388 TYR CA 428 1VED... A 1VEDA ASP CA 290 1VED A 1VED... CA 249 GLU CA 193 GLN CA 219 TRP CA 312 1VED

  18. Removal of Perchlorate from Water and Wastewater by Catalytic Hydrogen Gas Membrane Systems

    Science.gov (United States)

    2007-01-01

    Quimica , Serie A: Quimica Fisica e Ingenieria Quimica , 1984. 80(2): p. 219-25. Logan, B.E. and D. LaPoint, Treatment of Perchlorate- and Nitrate...ion at iridium electrodes. Ion concentration and solution pH effects. Anales de Quimica , Serie A: Quimica Fisica e Ingenieria Quimica (1985), 81(3

  19. EST Table: BW999179 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available BW999179 SES2517 10/09/28 84 %/219 aa ref|NP_001040215.1| stathmin [Bombyx mori] gb|ABD36259.1| stathmin...7-PA 10/09/10 51 %/223 aa gi|91083957|ref|XP_975021.1| PREDICTED: similar to stathmin [Tribolium castaneum] FS915193 L8 ...

  20. The association between metacarpal ratio, radiographic hand and knee osteoarthritis and its progression after meniscectomy

    DEFF Research Database (Denmark)

    Paradowski, P T; Lohmander, Stefan; Englund, Martin Kristian

    2013-01-01

    OBJECTIVE: To examine whether the ratio of the second and fourth metacarpal bone length (MC2:MC4) in subjects with prior meniscectomy of the knee is associated with radiographic hand and knee osteoarthritis (OA) and its progression. DESIGN: We assessed 219 subjects (175 men and 44 women) twice...

  1. AcEST: DK953053 [AcEST

    Lifescience Database Archive (English)

    Full Text Available .18 sp|Q01202|MYSP_BRUMA Paramyosin OS=Brugia malayi PE=2 SV=2 33 1.6 sp|Q11IG3|Y1416_MESSB UPF0283 membrane...ct: 168 DQLKKDKHLAEKAAERFEAQTVELSNKVEDLNRHVNDLAQQRQRLQAENNDL 219 >sp|Q11IG3|Y1416_MESSB UPF0283 membrane pro

  2. Disaster Preparedness Utilization Field/Disaster Preparedness Career Ladder, AFSCs 05XX/242X0

    Science.gov (United States)

    1988-11-01

    STG219, N=12) PERCENT MEMBERS TASKS PERFORMING E285 TYPE CORRESPONDENCE, SUCH AS REPORTS OR RECORDS 100 E252 MAINTAIN DISASTER PREPAREDNESS (DP...TECHNICAL ORDER FILES 67 E252 MAINTAIN DISASTER PREPAREDNESS (DP) OFFICE ADMINISTRATIVE FILES 56 A9 TABLE AlO REPRESENTATIVE TASKS PLRFORMED BY CONTROL

  3. Identification of novel RFLPs in the vicinity of CpG islands in Xq28: application to the analysis of the pattern of X chromosome inactivation.

    Science.gov (United States)

    Maestrini, E; Rivella, S; Tribioli, C; Rocchi, M; Camerino, G; Santachiara-Benerecetti, S; Parolini, O; Notarangelo, L D; Toniolo, D

    1992-01-01

    Probes for CpG islands were cloned from the distal long arm of the human X chromosome; three of them were found to be polymorphic. A HindIII RFLP was identified by the probe 2-25 (DXS606), and it was mapped to the Xq27-Xq28 boundary. Probes 2-19 (DXS605) and 2-55 (DXS707), which identify EcoRI and MspI polymorphisms, respectively, have been mapped to the distal part of Xq28, in the G6PD-RCP/GCP gene region. Probe 2-19 has been further localized about 16 kb from the 3' end of the G6PD gene. The new RFLPs may be useful for the precise mapping of the many disease genes localized in this part of the human X chromosome. Probe 2-19 is highly informative, and it has been studied in greater detail. Using the methylation-sensitive rare-cutter enzyme EagI in conjunction with the polymorphic EcoRI site, we were able to demonstrate that the RFLP may be used both to study randomness of X chromosome inactivation and for carrier detection in X-linked syndromes where nonrandom X inactivation occurs. It is conceivable that the combined use of 2-19 and of the probes described so far (pSPT-PGK and M27 beta) will make analysis of X inactivation feasible in virtually every female.

  4. 75 FR 11870 - Notice of Proposed Information Collection Requests

    Science.gov (United States)

    2010-03-12

    ... and usage, library technology, library budget and expenditures for 4,300 academic libraries in the U.S... Type of Review: Reinstatement. Title: Academic Libraries Survey (ALS): 2010-2012. Frequency: Biennially... Recordkeeping Hour Burden: Responses: 2,219. Burden Hours: 18,265. Abstract: The Academic Libraries Survey...

  5. GETDB: 104241 [GETDB

    Lifescience Database Archive (English)

    Full Text Available ring, AIII ring, distal leg, muscle in coxa, trochanter, tibia. wing vein. - - comment1:B, D, comment...wn as - Original Comments comment1:B, D, comment2:19A Disc (Image) d1 d2 d3 d4 Disc (number) 4 Embryo (Image

  6. Micromechanical Disk Array for Enhanced Frequency Stability Against Bias Voltage Fluctuations

    Science.gov (United States)

    2014-11-20

    sense of humor . I would also like to thank Professor Liwei Lin for reading this research report. His course ME219 (Parametric and Optimal Design of...work provides designers with needed visual cues that enable them to more intelligently choose device topologies to maximize the performance of

  7. Evaluating the Effectiveness of a School-Based Counselling Service in the UK

    Science.gov (United States)

    Fox, Claire L.; Butler, Ian

    2009-01-01

    Despite the growth of school counselling in the UK, very few studies have examined its effectiveness. As part of a wider evaluation of the work of the NSPCC Schools Counselling Project, 219 pupils aged 11-17 years completed the TEEN CORE questionnaire before receiving counselling; 104 of these pupils also completed a questionnaire after…

  8. EST Table: FS733616 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available FS733616 E_FL_bmmt_21O09_F_0 10/09/28 100 %/219 aa ref|NP_001136399.1| kynureninase... [Bombyx mori] dbj|BAH03383.1| kynureninase [Bombyx mori] 10/09/03 n.h 10/08/28 33 %/232 aa C15H9.7#CE06835#WBGene00015802#kynure

  9. 78 FR 36817 - Proposed Agency Information Collection Activities; Comment Request

    Science.gov (United States)

    2013-06-19

    ... feature of a warning system loses its effectiveness if the system is not repaired within a reasonable... employers with the prohibition against the abuse of alcohol and controlled substances. Because of the... the United States, FRA seeks to apply all of the requirements of 49 CFR 219 to FRFB train...

  10. 78 FR 18668 - Proposed Agency Information Collection Activities; Comment Request

    Science.gov (United States)

    2013-03-27

    .... Therefore, the fail-safe feature of a warning system loses its effectiveness if the system is not repaired... determine compliance of FRFB train and dispatching service employees and their employers with the..., FRA seeks to apply all of the requirements of 49 CFR part 219 to FRFB train and dispatching...

  11. 16 CFR 1512.5 - Requirements for braking system.

    Science.gov (United States)

    2010-01-01

    ... highest gear ratio at a pedal crank rate of 60 revolutions per minute), 3 the stopping distance shall be 4... gear development greater than 6.67 m (21.9 ft) in the bicycle's highest gear ratio. Gear development is... crank shall be not more than 60° with the crank held against each position under a torque of no...

  12. What Can We Learn from Toddlers about Categorical Perception of Color? Comments on Goldstein, Davidoff, and Roberson

    Science.gov (United States)

    Franklin, Anna; Wright, Oliver; Davies, Ian R. L.

    2009-01-01

    We comment on Goldstein, Davidoff, and Roberson's replication and extension ("Journal of Experimental Child Psychology, 102", 219-238 [2009]) of our study of the effect of toddlers' color term knowledge on their categorical perception (CP) of color ("Journal of Experimental Child Psychology, 90", 114-141 [2005]). First, we discuss how best to…

  13. Contrasting adolescent female and male sexual aggression: A self-report study on prevalence and predictors of sexual aggression

    NARCIS (Netherlands)

    Slotboom, A.-M.; Hendriks, J.; Verbruggen, J.

    2011-01-01

    In this study we investigated the prevalence of sexual aggression as reported by adolescent males and females in the Netherlands. Data were collected from a low-risk school-based sample (n=219; 119 adolescent females and 100 adolescent males), a medium-risk school-based sample (vocational training)

  14. A Chance in Hell: Evaluating the Efficacy of U.S. Military Health Systems in Foreign Disaster Relief

    Science.gov (United States)

    2013-12-10

    economy . Free pharmaceuticals created a black market and aggressive evacuation created 219U.S. Department of the Navy, Humanitarian Assistance/Disaster...262 In 2004, such a capability could have dispatched assessment teams from the joint task-force headquarters near Bangkok , Thailand directly to

  15. Search for New Quantum Algorithms

    Science.gov (United States)

    2006-05-01

    Topological computing for beginners, (slide presentation), Lecture Notes for Chapter 9 - Physics 219 - Quantum Computation. (http...14 II.A.8. A QHS algorithm for Feynman integrals ......................................................18 II.A.9. Non-abelian QHS algorithms -- A...idea is that NOT all environmentally entangling transformations are equally likely. In particular, for spatially separated physical quantum

  16. Palmyra Atoll Site 15P 3/31/2004 24-25M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 24 and 25 meters along a permanent transect.

  17. Palmyra Atoll Site 15P 8/11/2006 65-66M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 65 and 66 meters along a permanent transect.

  18. Palmyra Atoll Site 15P 3/31/2004 90-91M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 90 and 91 meters along a permanent transect.

  19. Palmyra Atoll Site 15P 8/11/2006 54-55M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 54 and 55 meters along a permanent transect.

  20. What Proportion of Preschool-Aged Children Consume Sweetened Beverages?

    Science.gov (United States)

    Nickelson, Jen; Lawrence, Jeannine C.; Parton, Jason M.; Knowlden, Adam P.; McDermott, Robert J.

    2014-01-01

    Background: Obesity affects nearly 17% of US children and youth 2-19?years old and 10% of infants and toddlers under the age of 2?years. One strategy for addressing obesity is to discourage sugar-sweetened beverage (SSB) consumption. Compared with their older school-aged counterparts, children =5?years depend largely on parents for the purchase…

  1. PHENOBARBITAL FOR THE PREVENTION OF INTRACRANIAL DAMAGE IN CHINESE NEONATES WITH SEVERE ASPHYXIA

    Institute of Scientific and Technical Information of China (English)

    陈惠金; 吴圣楣; 黄萍; 孙建华; 陈冠仪; 储淞雯

    2000-01-01

    R6sumeobjectiIPOurevaiuerlletprdventifduphenobarbitalsurleslesionsintracrdniennesasPhyxiquesainsiquelemalePilePtiquedesnouveau'nes.MdthodesUnessatcontr6leaeteportesur6onouveau-nesgravementasPhyxies.Ladose-chargedephenobarbitals,estfaitesur3Onouveau-ndsavantlngemOyende5.6heures.R/suItatsPasdedJfdrencesignilicativen'aetetrouveeconcernantpoidscorPorel,dgegestationel,scoresAPgaretsexneonataldesdeuxgrouPesdesnouveau-nes.LaconcentrationseriquedephdnobarbitalaetdenmOyenne21.9Pg/ml4joursaPrbslanaissance.Lesimagesso...

  2. Plan for Engineering and Design. Des Moines Recreational River and Greenbelt, Des Moines River, Iowa.

    Science.gov (United States)

    1986-03-01

    Geographic information will be stored in a computerized database. Regional clima - tology and local hydrology will be presented in the GDM to describe...HEALTH AND HUMAN " 219 POST ODFItS BUILDING SlieVeisl AMES. IOwA 50010 DIPAITMINT Of LABOR PHoNoE 159I) 232-9221 DPARTMtEi OF TRANISFOBlTATION October 11

  3. A Cross-Cultural Study of Children's Perceptions of Selected Religious Concepts.

    Science.gov (United States)

    Nazar, Fatima; Kouzekanani, Kamiar

    2003-01-01

    A survey of 219 children from a kindergarten in the United States and a Kuwaiti kindergarten and Indian private preschool in Kuwait examined children's perceptions of God, death, and the afterlife. The common responses of the children suggest that although different views of Islam, Christianity, and Hinduism may appear contradictory, they are all…

  4. 77 FR 71163 - Federal Motor Vehicle Safety Standards; Windshield Zone Intrusion

    Science.gov (United States)

    2012-11-29

    ... National Highway Traffic Safety Administration 49 CFR Part 571 RIN 2127-AK13 Federal Motor Vehicle Safety... rulemaking proposal to rescind Federal Motor Vehicle Safety Standard (FMVSS) No. 219, ``Windshield zone... members included: BMW Group, Chrysler LLC, Ford Motor Company, General Motors, Mazda, Mercedes-Benz...

  5. Public Health Implications of the 1540 nm Laser on the Cornea

    Science.gov (United States)

    2007-05-30

    7; 2003. Isnard N, Bourles-Dagonet F, Robert L, Renard G. Studies on corneal wound healing. Effect of fucose on iodine vapor-burnt rabbit corneas... Fucose On Iodine Vapor-Burnt Rabbit Corneas. Ophthalmologica 219, no. 6: 324-33. Jane’s international defense review. 2005. Jane’s. Jester, J. V., A

  6. Palmyra Atoll Site 15P 8/11/2006 9-10M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 9 and 10 meters along a permanent transect.

  7. Palmyra Atoll Site 15P 3/31/2004 48-49M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 48 and 49 meters along a permanent transect.

  8. Drug: D02107 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available Indiclor (TN) InCl3 219.8104 221.177 D02107.gif Radioactive agent Therapeutic category: 4300 Therapeutic ca...tegory of drugs in Japan [BR:br08301] 4 Agents affecting cellular function 43 Radioactive drugs 430 Radioactive drugs 4300 Radio

  9. 47 CFR 1.80 - Forfeiture proceedings.

    Science.gov (United States)

    2010-10-01

    ...), 219(b), 220(d), 223(b), 362(a), 362(b), 386(a), 386(b), 503(b), 506, and 634 of the Communications Act... unauthorized equipment 7,000 Exceeding of authorized antenna height 5,000 Fraud by wire, radio or television 5... under section 504 of the Act. The one exception is section 223 of the Act, which provides a...

  10. 77 FR 24415 - Inflation Adjustment of the Aggravated Maximum Civil Monetary Penalty for a Violation of a...

    Science.gov (United States)

    2012-04-24

    ... Federal Railroad Administration 49 CFR Parts 209, 213, 214, 215, 216, 217, 218, 219, 220, 221, 222, 223...); 49 CFR 240.223(a), (b). Further, FRA is revising language in 49 CFR part 209, appendix A, ``Statement..., Transportation. 49 CFR Part 220 Communications, Penalties, Radio, Railroad safety, Reporting and...

  11. Integrating Nutrition into the Physical Education Curriculum

    Science.gov (United States)

    Green, Heather L.

    2012-01-01

    Obesity among children and teens continues to be a major public health concern in the United States. Approximately 16.9% of children and adolescents age 2-19 years are obese. To address this epidemic, schools have been encouraged to develop a coordinated school health program, which includes an interdisciplinary approach to nutrition education.…

  12. Utility of the Rosenberg Self-Esteem Scale

    Science.gov (United States)

    Davis, Clare; Kellett, Stephen; Beail, Nigel

    2009-01-01

    The Rosenberg Self-Esteem Scale (RSES) continues to be used to purportedly measure self-esteem of people with intellectual disabilities, despite the lack of sound evidence concerning its validity and reliability when employed with this population. The psychometric foundations of the RSES were analyzed here with a sample of 219 participants with…

  13. Obesity and Socioeconomic Status in Children and Adolescents: United States, 2005-2008. NCHS Data Brief. Number 51

    Science.gov (United States)

    Ogden, Cynthia L.; Lamb, Molly M.; Carroll, Margaret D.; Flegal, Katherine M.

    2010-01-01

    In 2007-2008 almost 17% of children and adolescents aged 2-19 years were obese. Childhood obesity often tracks to adulthood and, in the short run, childhood obesity can lead to psychosocial problems and cardiovascular risk factors such as high blood pressure, high cholesterol, and abnormal glucose tolerance or diabetes. Studies have suggested that…

  14. Legal and Illegal Colours

    DEFF Research Database (Denmark)

    Larsen, John Christian

    2008-01-01

    ://www.efsa.europa.eu/EFSA/efsa_locale-1178620753812_1178620765743.htm. Accessed 12.05.08.] and parabens [EFSA. (2004). Opinion of the Scientific Panel on Food Additives, Flavourings, Processing Aids and Materials in Contact with Food (AFC) related to para hydroxybenzoates (214e219). Opinion expressed on 13/07/2004. Available at http...

  15. Gclust Server: 60460 [Gclust Server

    Lifescience Database Archive (English)

    Full Text Available 60460 DME_CG12057_24640756 Cluster Sequences - 219 CG12057: CG12057-PA 2 1.00e-99 0....0 0.0 0.0 0.0 0.0 12.5 Show 60460 Cluster ID 60460 Sequence ID DME_CG12057_24640756 Link to cluster sequenc

  16. 77 FR 58203 - In the Matter of the Designation of the Haqqani Network Also Known as HQN as a Foreign Terrorist...

    Science.gov (United States)

    2012-09-19

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE In the Matter of the Designation of the Haqqani Network Also Known as HQN as a Foreign Terrorist Organization Pursuant to Section 219 of the Immigration and Nationality Act, as Amended Based upon a review of the Administrative Record assembled in this...

  17. 77 FR 4082 - Review and Amendment of the Designation of al-Qa'ida in Iraq, et al. as a Foreign Terrorist...

    Science.gov (United States)

    2012-01-26

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Review and Amendment of the Designation of al-Qa'ida in Iraq, et al. as a Foreign Terrorist Organization Pursuant to Section 219 of the Immigration and Nationality Act In the Matter of the Review and Amendment of the Designation of al-Qa'ida in Iraq, aka...

  18. 75 FR 78336 - Review of the Designation of Gama'a al-Islamiyya, (IG and Other Aliases); as a Foreign Terrorist...

    Science.gov (United States)

    2010-12-15

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF STATE Review of the Designation of Gama'a al-Islamiyya, (IG and Other Aliases); as a Foreign Terrorist Organization Pursuant to Section 219 of the Immigration and Nationality Act, as Amended Based upon a review of the Administrative Record assembled in this...

  19. Palmyra Atoll Site 15P 3/31/2004 15-16M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 15 and 16 meters along a permanent transect.

  20. Palmyra Atoll Site 15P 3/31/2004 85-86M

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — One-meter-square (1 meter x 1 meter) benthic substrate at Palmyra Atoll, site 15P (05 52.219N, 162 02.697W), between 85 and 86 meters along a permanent transect.