WorldWideScience

Sample records for astatine 209

  1. Astatine-211: production and availability.

    Science.gov (United States)

    Zalutsky, Michael R; Pruszynski, Marek

    2011-07-01

    The 7.2-h half life radiohalogen (211)At offers many potential advantages for targeted α-particle therapy; however, its use for this purpose is constrained by its limited availability. Astatine-211 can be produced in reasonable yield from natural bismuth targets via the (209)Bi(α,2n)(211)At nuclear reaction utilizing straightforward methods. There is some debate as to the best incident α-particle energy for maximizing 211At production while minimizing production of (210)At, which is problematic because of its 138.4-day half life α-particle emitting daughter, (210)Po. The intrinsic cost for producing (211)At is reasonably modest and comparable to that of commercially available (123)I. The major impediment to (211)At availability is attributed to the need for a medium energy α-particle beam for its production. On the other hand, there are about 30 cyclotrons in the world that have the beam characteristics required for (211)At production. PMID:22201707

  2. Some aspects of the organic, biological and inorganic chemistry of astatine

    International Nuclear Information System (INIS)

    Astatine has no stable isotopes and the radioactive isotopes with half-lives sufficiently long for chemical experiments (209At, 210At, 211At) must be produced artificially with a cyclotron or with a high energy accelerator by spallation of Th. This thesis deals with the synthesis and chemistry of At-compounds and the determination of some of their properties. (C.F.)

  3. An attempt to explore the production routes of Astatine radionuclides: Theoretical approach

    OpenAIRE

    Maiti, Moumita; Lahiri, Susanta

    2008-01-01

    In order to fulfil the recent thrust of Astatine radionuclides in the field of nuclear medicine various production routes have been explored in the present work. The possible production routes of $^{209-211}$At comprise both light and heavy ion induced reactions at the bombarding energy range starting from threshold to maximum 100 MeV energy. For this purpose, we have used the nuclear reaction model codes TALYS, ALICE91 and PACE-II. Excitation functions of those radionuclides, produced throug...

  4. Bibliography of astatine chemistry and biomedical applications

    International Nuclear Information System (INIS)

    An overall bibliography is presented on astatine chemistry and on the biomedical applications of its 211At isotope. The references were grouped in the following chapters: General reviews; Discovery, Natural Occurence; Nuclear Data; Preparation, Handling, Radiation Risk; Physico-chemical Properties; Astatine Compounds and Chemical Reactions; Biological Effects and Applications. Entries are sorted alphabetically by authors name in each chapter, and cross-references to other chapters are provided if appropriate. (R.P.)

  5. Adsorption interaction of astatine species with quartz and gold surfaces

    Energy Technology Data Exchange (ETDEWEB)

    Serov, A. [Paul Scherrer Institute, Villigen (Switzerland). Lab. for Radiochemistry and Environmental Chemistry; Bern Univ. (Switzerland). Dept. for Chemistry and Biochemistry; Aksenov, N.; Bozhikov, G. [Joint Institute for Nuclear Research, Dubna (RU). Flerov Lab. of Nuclear Reactions] (and others)

    2011-07-01

    The adsorption interaction of various astatine species with quartz and gold surfaces was investigated by gas chromatography methods. Due to variations of the redox potential of the carrier gas elemental astatine, astatine oxide and hypo-astatic acid have been produced. The identification of the astatine compounds is based on the analogy assumption to the gas phase chemistry of the closest homologues in group 17 of the periodic table, iodine and bromine. The deposition temperatures as well as enthalpies of adsorption have been determined for the astatine species. The enhancement of the metallic character within group 17 towards higher Z is clearly confirmed. Macroscopic properties (sublimation enthalpy) of previously unstudied AtO{sub 2} and HAtO were estimated. The determined data for elemental astatine were compared to available literature data. Based on the obtained experimental results possible designs of experiments for studying of chemical properties of the recently discovered element 117 can be suggested. (orig.)

  6. Recent advances in the organic chemistry of astatine

    International Nuclear Information System (INIS)

    Investigation on the chemical behaviour of astatine in the last decade are surveyed. The survey covers the physical and chemical properties of astatine, synthesis and identification of organic astatine compounds, their physicochemical properties. A special chapter is devoted to biomedical applications, including inorganic 211At species, 211At-labelled proteins and drugs. An extensive bibliography of the related literature is given. (N.T.) 129 refs.; 12 figs.; 14 tabs

  7. Astatine-211 Pathway from Radiochemistry to Clinical Investigation

    International Nuclear Information System (INIS)

    Particularly in clinical settings where tumour burden is low and cancers are located in close proximity to essential normal tissue structures, α-particle emitting radionuclides can offer significant advantages for targeted radionuclide therapy. One of the first alpha emitters to be evaluated for this purpose is the 7.2-h half-life radiohalogen Astatine-211 (211At). From a commercialization-potential perspective 211At, is less appealing than the longer half-life alpha particle emitters Radium-223, Actinium-225 and Thorium-227, which have become the focus of many laboratories. However, if methods for providing a better supply of 211At could be developed, this alpha emitter would be the radionuclide of choice for many potential therapeutic applications. With regard to the production of 211At, this can be readily be accomplished by bombarding natural bismuth targets with 28−29.5 MeV alpha particles via the 209Bi(α,2n)211At reaction. The goal is to utilize an alpha particle beam energy that provides the required balance for maximizing 211At production while minimizing creation of 210At, which is problematic because of its 138.4-day half life alpha-particle emitting daughter, 210Po. For most intended clinical applications, alpha particle beam energy of about 29 MeV offers the best compromise between maximizing yield and providing 211At with sufficient radionuclidic purity for clinical use. Clinically relevant levels of 211At have been produced at several institutions using both internal and external cyclotron targets

  8. Discovery of the astatine, radon, francium, and radium isotopes

    CERN Document Server

    Fry, C

    2012-01-01

    Currently, thirty-nine astatine, thirty-nine radon, thirty-five francium, and thirty-four radium isotopes have so far been observed; the discovery of these isotopes is discussed. For each isotope a brief summary of the first refereed publication, including the production and identification method, is presented.

  9. Extraction of astatine isotopes for development of radiopharmaceuticals using a 211Rn-211At generator

    International Nuclear Information System (INIS)

    In order to utilize a 211At isotope, a promising α-emitter for radionuclide therapy, the chemical properties of astatine isotopes are studied. We have examined wet chemistry methods through the distribution ratios of astatine in liquid-liquid extraction. The astatine isotopes have been found to be well extracted into DIPE and MIBK. We observed that the distribution ratio of astatine isotopes increases with concentrations of HCl greater than 3 M, while it decreases with the HCl concentration less than 2 M. The results will be useful for development of the 211Rn-211At generator. (author)

  10. Astatine-211-Labeled Targeted Radiotherapeutics: An Update

    International Nuclear Information System (INIS)

    The heavy halogen 211At was first proposed for use in α-particle targeted radiotherapy more than 30 years ago and continues to be one of the most promising radionuclides for this purpose. Although its 7.2-h half life is not ideal for intravenously administered whole antibodies, it is compatible with the pharmacokinetics of antibody fragments, peptides, aptamers and organic molecules. Its diverse chemistry allows its incorporation into a wide array of targeting vehicles, relying on its chemical similarity to iodine to provide a useful point of departure. On the other hand, the relatively low carbon-astatine bond strength is challenging. In common with the other α-emitters being discussed at this symposium, lack of reliable availability is one of the biggest hurdles in the use of 211At for targeted radiotherapy. However, in the case of 211At, it is not a question of production cost or availability of target material, because 211At can be produced in reasonable yield from natural bismuth targets. Rather, the difficulty is the lack of cyclotrons equipped with the medium energy α-particle beams required for its production. If the infrastructure for producing 211At is to be improved to the stage where 211At-labeled radiopharmaceuticals can have a meaningful impact, several developments must occur. First, the ability to produce clinically relevant levels of 211At that can be shipped to remote locations in chemically tractable form must be demonstrated. Approaches under consideration include compensating for radiolysis-mediated effects and the consideration of alternative chemistries. Second, strategies for compensating for heterogeneities in dose deposition must be developed, hopefully in a way that is compatible with approval for human use. And third, it is essential that more clinical trials be performed with 211At-labeled therapeutics, particularly in settings of minimum residual disease where the radiobiological advantages of α-particles can be best exploited. Our

  11. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    CERN Document Server

    Rothe, S; Antalic, S; Borschevsky, A; Capponi, L; Cocolios, T E; De Witte, H; Eliav, E; Fedorov, D V; Fedosseev, V N; Fink, D A; Fritzsche, S; Ghys, L; Huyse, M; Imai, N; Kaldor, U; Kudryavtsev, Yu; Köster, U; Lane, J; Lassen, J; Liberati, V; Lynch, K M; Marsh, B A; Nishio, K; Pauwels, D; Pershina, V; Popescu, L; Procter, T J; Radulov, D; Raeder, S; Rajabali, M M; Rapisarda, E; Rossel, R E; Sandhu, K; Seliverstov, M D; Sjödin, A M; Van den Bergh, P; Van Duppen, P; Venhart, M; Wakabayashi, Y; Wendt K D A

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of smallest quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the ionization threshold. The observed series of Rydberg states enabled the first determination of the ionization potential of the astatine atom, 9.317510(8) eV. New ab initio calculations were performed to support the experimental result. The measured value serves as a benchmark for quantum chemistry calculations of the properties of astatine as well as for the theoretical prediction of the ionization potential of super-heavy element 117, the heaviest homologue of astatine.

  12. Synthesis and Evaluation of Astatinated N-[2-(Maleimido)ethyl]-3-(trimethylstannyl)benzamide Immunoconjugates.

    Science.gov (United States)

    Aneheim, Emma; Gustafsson, Anna; Albertsson, Per; Bäck, Tom; Jensen, Holger; Palm, Stig; Svedhem, Sofia; Lindegren, Sture

    2016-03-16

    Effective treatment of metastasis is a great challenge in the treatment of different types of cancers. Targeted alpha therapy utilizes the short tissue range (50-100 μm) of α particles, making the method suitable for treatment of disseminated occult cancers in the form of microtumors or even single cancer cells. A promising radioactive nuclide for this type of therapy is astatine-211. Astatine-211 attached to tumor-specific antibodies as carrier molecules is a system currently under investigation for use in targeted alpha therapy. In the common radiolabeling procedure, astatine is coupled to the antibody arbitrarily on lysine residues. By instead coupling astatine to disulfide bridges in the antibody structure, the immunoreactivity of the antibody conjugates could possibly be increased. Here, the disulfide-based conjugation was performed using a new coupling reagent, maleimidoethyl 3-(trimethylstannyl)benzamide (MSB), and evaluated for chemical stability in vitro. The immunoconjugates were subsequently astatinated, resulting in both high radiochemical yield and high specific activity. The MSB-conjugate was shown to be stable with a long shelf life prior to the astatination. In a comparison of the in vivo distribution of the new immunoconjugate with other tin-based immunoconjugates in tumor-bearing mice, the MSB conjugation method was found to be a viable option for successful astatine labeling of different monoclonal antibodies. PMID:26791409

  13. At R209

    CERN Multimedia

    1977-01-01

    Side view of R209, showing a large muon chamber in front of the Iron toroid magnet. Gunter Feilhauer is looking down from top of the magnet. Ulrich Becker (left), Lars Leistam (right) stand on the floor.

  14. Measurement of the first ionization potential of astatine by laser ionization spectroscopy

    OpenAIRE

    Rothe, S.; A. N. Andreyev; Antalic, S; Borschevsky, A.; Capponi, L.; Cocolios, T.E.; Witte, H.; Eliav, E.; Fedorov, D. V.; Fedosseev, V. N.; Fink, D. A.; Fritzsche, S.; Ghys, L.; Huyse, M.; Imai, N.

    2013-01-01

    The radioactive element astatine exists only in trace amounts in nature. Its properties can therefore only be explored by study of the minute quantities of artificially produced isotopes or by performing theoretical calculations. One of the most important properties influencing the chemical behaviour is the energy required to remove one electron from the valence shell, referred to as the ionization potential. Here we use laser spectroscopy to probe the optical spectrum of astatine near the io...

  15. Comment: 209 [Taxonomy Icon

    Lifescience Database Archive (English)

    Full Text Available Anopheles stephensi Anopheles stephensi Anopheles_stephensi_L.png 209.png Public Domain CDC(Cen...ters for Disease Control and Prevention)のimage libraryから(Public Domain) http://phil.cdc.gov/phil/home.asp bando 2010/02/15 14:46:05 2010/02/15 14:49:04 ...

  16. Automated astatination of biomolecules - a stepping stone towards multicenter clinical trials

    DEFF Research Database (Denmark)

    Aneheim, Emma; Albertsson, Per; Bäck, Tom;

    2015-01-01

    To facilitate multicentre clinical studies on targeted alpha therapy, it is necessary to develop an automated, on-site procedure for conjugating rare, short-lived, alpha-emitting radionuclides to biomolecules. Astatine-211 is one of the few alpha-emitting nuclides with appropriate chemical...... and physical properties for use in targeted therapies for cancer. Due to the very short range of the emitted α-particles, this therapy is particularly suited to treating occult, disseminated cancers. Astatine is not intrinsically tumour-specific; therefore, it requires an appropriate tumour-specific targeting...... vector, which can guide the radiation to the cancer cells. Consequently, an appropriate method is required for coupling the nuclide to the vector. To increase the availability of astatine-211 radiopharmaceuticals for targeted alpha therapy, their production should be automated. Here, we present a method...

  17. Study of Astatine (III) reactions with O, S and N ligands in solution

    International Nuclear Information System (INIS)

    Full text of publication follows. Astatine (At, Z=85: [Xe]4f145d106s26p5) belongs to the halogen group and is located below iodine in the periodic table. One of its isotopes (211At) appears promising as a therapeutic agent in nuclear medicine (Ref.1) owing to the energy of the alpha particles emitted during the disintegration of its nucleus and its short physical half-life (7.2 h). Since there are no stable isotopes of astatine, the chemistry of this element remains poorly understood. Generally, At is supposed to behave as a halogen (Ref.2) but it has been shown recently in our group that astatine presents a metallic behaviour in aqueous solution: it notably exists as At+ and AtO+ species under the oxidation states +I and +III (Ref.3). At the present time, the number of studies dealing with the complexation properties of the cationic forms of astatine remains limited (Ref.4), owing to its low availability. In this work, we have investigated the reactions of AtO+ species with different hetero-atomic (N, S, O) model ligands. A combined approach based on experimental and theoretical studies has been used (Ref.5). On account of the difficulties of experimental investigations of astatine species, the reactivity of AtO+ was explored using a competition method founded on astatine distributions between two distinct phases. Furthermore, for each AtO+/ ligand complex, the nature of the species formed and the associated thermodynamic constants were determined by computational modeling (DFT calculations). In this framework, an original computational methodology was developed to take into account the specificities of astatine, notably the associated relativistic effects. The computed equilibrium constants have been confronted with the experimental results. This comparison demonstrates an outstanding coherence between experience and theory. Furthermore, the analysis of the results shows a key role of solvent effects on astatine chemistry. Lastly, a specific reactivity for the

  18. A Concise Synthesis of (-)-Indolizidines 209D and 209B

    Institute of Scientific and Technical Information of China (English)

    WU Hao; YU Menglong; ZHANG Yazhu; ZHAO Gang

    2009-01-01

    A general stereoselective synthetic route to 5-substituted and 5,8-disubstituted indolizidine alkaloids has been developed starting from commercially available L-proline. (-)-lndolizidines 209D and 209B were efficiently syn-thesized in 9.8% and 14.8% overall yields in seven and five-step reactions from readily available aldehyde 3 and ketone 10, respectively. The key steps of this synthesis involve a substrate-induced asymmetric addition of ethyl lithiopropiolate to aldehyde 3 or methyl ketone 10, and a two-step one-pot hydrogenation/cyclization sequence to construct the bicyclic skeleton.

  19. 48 CFR 209.407 - Suspension.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Suspension. 209.407... OF DEFENSE ACQUISITION PLANNING CONTRACTOR QUALIFICATIONS Debarment, Suspension, and Ineligibility 209.407 Suspension....

  20. 48 CFR 209.104 - Standards.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Standards. 209.104 Section 209.104 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM, DEPARTMENT OF... Standards....

  1. 40 CFR 209.26 - Evidence.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Evidence. 209.26 Section 209.26... Orders Issued Under Section 11(d) of the Noise Control Act § 209.26 Evidence. (a) The official... record. Evidence may be received at the hearing even though inadmissible under the rules of...

  2. 7 CFR 868.209 - Information.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Information. 868.209 Section 868.209 Agriculture... Application of Standards § 868.209 Information. Requests for the Rice Inspection Handbook, Equipment Handbook, or for information concerning approved devices and procedures, criteria for approved devices,...

  3. 33 CFR 117.209 - Mianus River.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Mianus River. 117.209 Section 117.209 Navigation and Navigable Waters COAST GUARD, DEPARTMENT OF HOMELAND SECURITY BRIDGES DRAWBRIDGE OPERATION REGULATIONS Specific Requirements Connecticut § 117.209 Mianus River. The draw of the...

  4. 40 CFR 209.12 - Time.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Time. 209.12 Section 209.12 Protection... Issued Under Section 11(d) of the Noise Control Act § 209.12 Time. (a) In computing any period of time... period of time begins to run shall not be included, except as otherwise provided. Saturdays, Sundays,...

  5. 40 CFR 240.209 - Safety.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Safety. 240.209 Section 240.209 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.209 Safety....

  6. 40 CFR 240.209-1 - Requirement.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Requirement. 240.209-1 Section 240.209-1 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) SOLID WASTES GUIDELINES FOR THE THERMAL PROCESSING OF SOLID WASTES Requirements and Recommended Procedures § 240.209-1...

  7. 49 CFR 209.5 - Service.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Service. 209.5 Section 209.5 Transportation Other... TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES General § 209.5 Service. (a) Each order, notice, or other... mail, except as otherwise provided herein. (b) Service upon a person's duly authorized...

  8. 14 CFR 171.209 - Installation requirements.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 3 2010-01-01 2010-01-01 false Installation requirements. 171.209 Section 171.209 Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) NAVIGATIONAL FACILITIES NON-FEDERAL NAVIGATION FACILITIES VHF Marker Beacons § 171.209...

  9. 22 CFR 209.6 - Compliance information.

    Science.gov (United States)

    2010-04-01

    ... 22 Foreign Relations 1 2010-04-01 2010-04-01 false Compliance information. 209.6 Section 209.6... § 209.6 Compliance information. (a) Cooperation and assistance. The Administrator shall to the fullest... and accurate compliance reports at such times, and in such form and containing such information,...

  10. 42 CFR 59.209 - Civil rights.

    Science.gov (United States)

    2010-10-01

    ... issued by the Secretary of Health and Human Services with the approval of the President (45 CFR part 80). ... 42 Public Health 1 2010-10-01 2010-10-01 false Civil rights. 59.209 Section 59.209 Public Health... Grants for Family Planning Service Training § 59.209 Civil rights. Attention is called to...

  11. 23 CFR 650.209 - Construction.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Construction. 650.209 Section 650.209 Highways FEDERAL..., STRUCTURES, AND HYDRAULICS Erosion and Sediment Control on Highway Construction Projects § 650.209 Construction. (a) Permanent erosion and sediment control measures and practices shall be established...

  12. Determination of the electron affinity of astatine and polonium by laser photodetachment

    CERN Multimedia

    We propose to conduct the first electron anity (EA) measurements of the two elements astatine (At) and polonium (Po). Collinear photodetachment spectroscopy will allow us to measure these quantities with an uncertainty limited only by the spectral linewidth of the laser. We plan to use negative ion beams of the two radioactive elements At and Po, which are only accessible on-line and at ISOLDE. The feasibility of our proposed method and the functionality of the experimental setup have been demonstrated at ISOLDE in o-line tests by the clear observation of the photodetachment threshold for stable iodine. This proposal is based on our Letter of Intent I-148 [1].

  13. 48 CFR 209.570-2 - Policy.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Policy. 209.570-2 Section... 209.570-2 Policy. (a) Except as provided in paragraph (b) of this subsection, 10 U.S.C. 2410p... Authorization Act for Fiscal Year 2008 (Pub. L. 110-181), DoD may award a new contract for lead...

  14. 44 CFR 209.2 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... project, in accordance with FEMA guidance and using a FEMA-approved methodology. FEMA will review the... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Definitions. 209.2 Section 209.2 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY, DEPARTMENT OF...

  15. 31 CFR 800.209 - Critical technologies.

    Science.gov (United States)

    2010-07-01

    ... 31 Money and Finance: Treasury 3 2010-07-01 2010-07-01 false Critical technologies. 800.209..., AND TAKEOVERS BY FOREIGN PERSONS Definitions § 800.209 Critical technologies. The term critical technologies means: (a) Defense articles or defense services covered by the United States Munitions List...

  16. 24 CFR 941.209 - Audit.

    Science.gov (United States)

    2010-04-01

    ... HOUSING DEVELOPMENT PHA Eligibility and Program Requirements § 941.209 Audit. All PHAs that receive funds under this part for the development of low-income housing shall comply with audit requirements in 24 CFR... 24 Housing and Urban Development 4 2010-04-01 2010-04-01 false Audit. 941.209 Section...

  17. 7 CFR 62.209 - Reassessment.

    Science.gov (United States)

    2010-01-01

    ... AGRICULTURAL COMMODITIES (QUALITY SYSTEMS VERIFICATION PROGRAMS) Quality Systems Verification Programs Definitions Service § 62.209 Reassessment. Approved programs are subject to periodic reassessments to ensure... Regulations of the Department of Agriculture (Continued) AGRICULTURAL MARKETING SERVICE...

  18. 5 CFR 551.209 - Creative professionals.

    Science.gov (United States)

    2010-01-01

    ... 551.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT CIVIL SERVICE REGULATIONS PAY... performance of work requiring invention, imagination, originality, or talent in a recognized field of artistic..., imagination, originality, or talent” distinguishes the creative professions from work that primarily...

  19. AcEST: CL209Contig1 [AcEST

    Lifescience Database Archive (English)

    Full Text Available CL209Contig1 887 10 Adiantum capillus-veneris contig: CL209contig1 sequence. Link to clone list Show CL209C...ontig1 Contig ID CL209Contig1 Length 887 Number of clones 10 Definition Adiantum cap...illus-veneris contig: CL209contig1 sequence. Link to clone list Link to clone list Clone ID DK946036 DK94588

  20. 49 CFR 571.209 - Standard No. 209; Seat belt assemblies.

    Science.gov (United States)

    2010-10-01

    ....1 of Standard No. 208 (49 CFR 571.208) by virtue of S4.1.2.1(c)(2) of Standard No. 208 does not have... Motor Vehicle Safety Standards § 571.209 Standard No. 209; Seat belt assemblies. S1. Purpose and scope.... S3. Definitions. Adjustment hardware means any or all hardware designed for adjusting the size of...

  1. Unexpected Behavior of the Heaviest Halogen Astatine in the Nucleophilic Substitution of Aryliodonium Salts.

    Science.gov (United States)

    Guérard, François; Lee, Yong-Sok; Baidoo, Kwamena; Gestin, Jean-François; Brechbiel, Martin W

    2016-08-22

    Aryliodonium salts have become precursors of choice for the synthesis of (18) F-labeled tracers for nuclear imaging. However, little is known on the reactivity of these compounds with heavy halides, that is, radioiodide and astatide, at the radiotracer scale. In the first comparative study of radiohalogenation of aryliodonium salts with (125) I(-) and (211) At(-) , initial experiments on a model compound highlight the higher reactivity of astatide compared to iodide, which could not be anticipated from the trends previously observed within the halogen series. Kinetic studies indicate a significant difference in activation energy (Ea =23.5 and 17.1 kcal mol(-1) with (125) I(-) and (211) At(-) , respectively). Quantum chemical calculations suggest that astatination occurs via the monomeric form of an iodonium complex whereas iodination occurs via a heterodimeric iodonium intermediate. The good to excellent regioselectivity of halogenation and high yields achieved with diversely substituted aryliodonium salts indicate that this class of compounds is a promising alternative to the stannane chemistry currently used for heavy radiohalogen labeling of tracers in nuclear medicine. PMID:27305065

  2. 47 CFR 53.209 - Biennial audit.

    Science.gov (United States)

    2010-10-01

    ... necessary to ensure compliance with the audit requirements listed in paragraph (b) of this section. If the... independent auditor to take any actions necessary to ensure compliance with the audit requirements in... 47 Telecommunication 3 2010-10-01 2010-10-01 false Biennial audit. 53.209 Section...

  3. 14 CFR 67.209 - Neurologic.

    Science.gov (United States)

    2010-01-01

    ... Aeronautics and Space FEDERAL AVIATION ADMINISTRATION, DEPARTMENT OF TRANSPORTATION (CONTINUED) AIRMEN MEDICAL STANDARDS AND CERTIFICATION Second-Class Airman Medical Certificate § 67.209 Neurologic. Neurologic standards for a second-class airman medical certificate are: (a) No established medical history or...

  4. 48 CFR 209.406-2 - Causes for debarment.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Causes for debarment. 209.406-2 Section 209.406-2 Federal Acquisition Regulations System DEFENSE ACQUISITION REGULATIONS SYSTEM... 209.406-2 Causes for debarment. (1) Any person shall be considered for debarment if...

  5. 49 CFR 382.209 - Use following an accident.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 5 2010-10-01 2010-10-01 false Use following an accident. 382.209 Section 382.209... ALCOHOL USE AND TESTING Prohibitions § 382.209 Use following an accident. No driver required to take a post-accident alcohol test under § 382.303 shall use alcohol for eight hours following the accident,...

  6. 46 CFR 69.209 - Calculation of tonnages.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Calculation of tonnages. 69.209 Section 69.209 Shipping... MEASUREMENT OF VESSELS Simplified Measurement System § 69.209 Calculation of tonnages. (a) Gross tonnage. (1... percent of that depth is used for gross tonnage calculations. (b) Net tonnage. (1) For a vessel...

  7. 41 CFR 101-27.209-1 - GSA stock items.

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 2 2010-07-01 2010-07-01 true GSA stock items. 101-27.209-1 Section 101-27.209-1 Public Contracts and Property Management Federal Property Management...-Management of Shelf-Life Materials § 101-27.209-1 GSA stock items. Shelf-life items that meet the...

  8. 49 CFR 209.131 - Criminal penalties generally.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Criminal penalties generally. 209.131 Section 209... Criminal Penalties § 209.131 Criminal penalties generally. A person who knowingly violates 49 U.S.C. 5104(b... hazardous material transportation law or a regulation, order, special permit, or approval issued...

  9. 50 CFR 665.209 - Fishing moratorium on Hancock Seamount.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 9 2010-10-01 2010-10-01 false Fishing moratorium on Hancock Seamount. 665.209 Section 665.209 Wildlife and Fisheries FISHERY CONSERVATION AND MANAGEMENT, NATIONAL OCEANIC... Hawaii Fisheries § 665.209 Fishing moratorium on Hancock Seamount. Fishing for Hawaii bottomfish...

  10. 46 CFR 153.209 - Bilge pumping systems.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Bilge pumping systems. 153.209 Section 153.209 Shipping COAST GUARD, DEPARTMENT OF HOMELAND SECURITY (CONTINUED) CERTAIN BULK DANGEROUS CARGOES SHIPS CARRYING... Requirements § 153.209 Bilge pumping systems. Bilge pumping systems for cargo pumprooms, slop tanks, and...

  11. 5 CFR 930.209 - Senior Administrative Law Judge Program.

    Science.gov (United States)

    2010-01-01

    ... 5 Administrative Personnel 2 2010-01-01 2010-01-01 false Senior Administrative Law Judge Program. 930.209 Section 930.209 Administrative Personnel OFFICE OF PERSONNEL MANAGEMENT (CONTINUED) CIVIL...) Administrative Law Judge Program § 930.209 Senior Administrative Law Judge Program. (a) OPM administers a...

  12. 30 CFR 77.209 - Surge and storage piles.

    Science.gov (United States)

    2010-07-01

    ... 30 Mineral Resources 1 2010-07-01 2010-07-01 false Surge and storage piles. 77.209 Section 77.209... Installations § 77.209 Surge and storage piles. No person shall be permitted to walk or stand immediately above a reclaiming area or in any other area at or near a surge or storage pile where the...

  13. 33 CFR 209.345 - Water resource policies and authorities.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Water resource policies and authorities. 209.345 Section 209.345 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.345 Water resource policies and authorities. Reimbursement for Advance...

  14. Laser spectroscopy of the ground state hyperfine splittings of $^{209}$Bi$^{82+}$ and $^{209}$Bi$^{80+}$

    CERN Document Server

    Lochmann, Matthias; Geppert, Christopher; Andelkovic, Zoran; Anielski, Denis; Botermann, Benjamin; Bussmann, Michael; Dax, Andreas; Frömmgen, Nadja; Hammen, Michael; Hannen, Volker; Kühl, Thomas; Litvinov, Yuri A; López-Coto, Rubén; Stöhlker, Thomas; Thompson, Richard C; Vollbrecht, Jonas; Volotka, Andrey; Weinheimer, Christian; Wen, Weiqiang; Will, Elisa; Winters, Danyal; Sánchez, Rodolfo; Nörtershäuser, Wilfried

    2014-01-01

    We performed a laser spectroscopic determination of the $2s$ hyperfine structure (HFS) splitting of lithiumlike $^{209}\\text{Bi}^{80+}$ for the first time and repeated the measurement of the $1s$ HFS splitting of hydrogenlike $^{209}\\text{Bi}^{82+}$. Both ion species were subsequently stored in the Experimental Storage Ring at GSI and cooled with an electron cooler at a velocity of $\\approx 0.71\\,c$. Pulsed laser excitation of the M1 HFS-transition was performed in anticollinear and collinear geometry for $^{209}\\text{Bi}^{82+}$ and $^{209}\\text{Bi}^{80+}$, respectively, and observed by fluorescence detection. We obtain $\\Delta E^{(1s)}= 5086.3(11)\\,\\textrm{meV}$ for $^{209}\\text{Bi}^{82+}$ and $\\Delta E^{(2s)}= 797.50(18)\\,\\textrm{meV}$ for $^{209}\\text{Bi}^{80+}$. A specific difference between the two splitting energies can be used to test QED calculations in the strongest static magnetic fields available in the laboratory independent of nuclear structure effects. Our results confirm the large relativistic ...

  15. Part I: $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with astatine beams; Part II: Delineating the island of deformation in the light gold isotopes by means of laser spectroscopy

    CERN Document Server

    Andreyev, Andrei

    2013-01-01

    Part I: $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with astatine beams; Part II: Delineating the island of deformation in the light gold isotopes by means of laser spectroscopy

  16. ASTATINE-211 RADIOCHEMISTRY: THE DEVELOPMENT OF METHODOLOGIES FOR HIGH ACTIVITY LEVEL RADIOSYNTHESIS

    Energy Technology Data Exchange (ETDEWEB)

    MICHAEL R. ZALUTSKY

    2012-08-08

    Targeted radionuclide therapy is emerging as a viable approach for cancer treatment because of its potential for delivering curative doses of radiation to malignant cell populations while sparing normal tissues. Alpha particles such as those emitted by 211At are particularly attractive for this purpose because of their short path length in tissue and high energy, making them highly effective in killing cancer cells. The current impact of targeted radiotherapy in the clinical domain remains limited despite the fact that in many cases, potentially useful molecular targets and labeled compounds have already been identified. Unfortunately, putting these concepts into practice has been impeded by limitations in radiochemistry methodologies. A critical problem is that the synthesis of therapeutic radiopharmaceuticals provides additional challenges in comparison to diagnostic reagents because of the need to perform radio-synthesis at high levels of radioactivity. This is particularly important for {alpha}-particle emitters such as 211At because they deposit large amounts of energy in a highly focal manner. The overall objective of this project is to develop convenient and reproducible radiochemical methodologies for the radiohalogenation of molecules with the {alpha}-particle emitter 211At at the radioactivity levels needed for clinical studies. Our goal is to address two problems in astatine radiochemistry: First, a well known characteristic of 211At chemistry is that yields for electrophilic astatination reactions decline as the time interval after radionuclide isolation from the cyclotron target increases. This is a critical problem that must be addressed if cyclotrons are to be able to efficiently supply 211At to remote users. And second, when the preparation of high levels of 211At-labeled compounds is attempted, the radiochemical yields can be considerably lower than those encountered at tracer dose. For these reasons, clinical evaluation of promising 211At

  17. Treatment of 209 cases of liver injury

    Institute of Scientific and Technical Information of China (English)

    麻晓林; 蒋耀光; 杨志焕

    2004-01-01

    Objective: To summarize the experience of the treatment of traumatic hepatorrhexis. Methods: The clinical data of 209 cases of liver trauma treated in the three affiliated hospitals of the Third Military Medical University from 1989 to 1999 were retrospectively analyzed. Among the 209 patients, 108 (51.7%) had Grade III or more severe liver injury. Operative treatment was performed in 186 cases and preservative treatment in 23. Results: In the operated group, 169 patients were cured. The complications occurred in 18 patients and 17 of them died. In the non-operated group, the complications occurred in 22 patients and only 1 of them died. Conclusions: Severe injury and delayed treatment are two major factors leading to death from liver injuries. Surgical intervention is still the principal measure to treat traumatic hepatorrhexis. The indications for non-operative treatment should be carefully selected.

  18. An all-solid state laser system for the laser ion sources RILIS and in-source laser spectroscopy of astatine at ISOLDE/CERN

    Energy Technology Data Exchange (ETDEWEB)

    Rothe, Sebastian

    2012-09-24

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE/CERN and at ISAC/TRIUMF radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  19. An all-solid state laser system for the laser ion sources RILIS and in-source laser spectroscopy of astatine at ISOLDE/CERN

    International Nuclear Information System (INIS)

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spectroscopy was performed at ISOLDE/CERN and at ISAC/TRIUMF radioactive ion beam facilities to develop an efficient and selective three-colour ionization scheme for the purely radioactive element astatine. A LabVIEW based monitoring, control and measurement system was conceived which enabled, in conjunction with Dual RILIS operation, the spectroscopy of high lying Rydberg states, from which the ionization potential of the astatine atom was determined for the first time experimentally.

  20. 20 CFR 209.16 - Disposal of payroll records.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Disposal of payroll records. 209.16 Section... RAILROAD EMPLOYERS' REPORTS AND RESPONSIBILITIES § 209.16 Disposal of payroll records. Employers may dispose of payroll records for periods subsequent to 1936, provided that the payroll records are more...

  1. 27 CFR 555.209 - Construction of type 3 magazines.

    Science.gov (United States)

    2010-04-01

    ... magazines. 555.209 Section 555.209 Alcohol, Tobacco Products, and Firearms BUREAU OF ALCOHOL, TOBACCO... Construction of type 3 magazines. A type 3 magazine is a “day-box” or other portable magazine. It must be fire-resistant, weather-resistant, and theft-resistant. A type 3 magazine is to be constructed of not less...

  2. 50 CFR 226.209 - Critical habitat for hawksbill turtle.

    Science.gov (United States)

    2010-10-01

    ... 50 Wildlife and Fisheries 7 2010-10-01 2010-10-01 false Critical habitat for hawksbill turtle. 226.209 Section 226.209 Wildlife and Fisheries NATIONAL MARINE FISHERIES SERVICE, NATIONAL OCEANIC AND... Critical habitat for hawksbill turtle. (a) Mona and Monito Islands, Puerto Rico—Waters surrounding...

  3. 33 CFR 209.220 - Flood control regulations.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Flood control regulations. 209..., DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.220 Flood control regulations. (a) Local protection... probable date of transfer. (b) Use of storage allocated for flood control or navigation at...

  4. 33 CFR 209.300 - Flood control regulations.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Flood control regulations. 209..., DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.300 Flood control regulations. (a) Regulations for the... authority contained in Section 3 of the Flood Control Act of June 22, 1936, as amended and supplemented,...

  5. 13 CFR 500.209 - Funding for the Program.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Funding for the Program. 500.209 Section 500.209 Business Credit and Assistance EMERGENCY OIL AND GAS GUARANTEED LOAN BOARD EMERGENCY OIL... of the Program to the Government. The Board will estimate the risk posed by the guaranteed loans...

  6. 13 CFR 400.209 - Funding for the Program.

    Science.gov (United States)

    2010-01-01

    ... 13 Business Credit and Assistance 1 2010-01-01 2010-01-01 false Funding for the Program. 400.209 Section 400.209 Business Credit and Assistance EMERGENCY STEEL GUARANTEE LOAN BOARD EMERGENCY STEEL... Government. The Board will estimate the risk posed by the guaranteed loans to the funds appropriated for...

  7. 7 CFR 1430.209 - Proof of market loss production.

    Science.gov (United States)

    2010-01-01

    ... Contract Program § 1430.209 Proof of market loss production. (a) A dairy operation entering into a MILC... 7 Agriculture 10 2010-01-01 2010-01-01 false Proof of market loss production. 1430.209 Section... operation's eligible production during the months of each fiscal year designated in the MILC. The...

  8. 12 CFR 209.3 - Cancellation of Reserve Bank stock.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 2 2010-01-01 2010-01-01 false Cancellation of Reserve Bank stock. 209.3... ISSUE AND CANCELLATION OF FEDERAL RESERVE BANK CAPITAL STOCK (REGULATION I) § 209.3 Cancellation of Reserve Bank stock. (a) Application for cancellation. Any bank that desires to withdraw from membership...

  9. 49 CFR 209.8 - Depositions in formal proceedings.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD SAFETY ENFORCEMENT PROCEDURES General § 209.8 Depositions... part, § 209.315. (b) Any party desiring to take the deposition of a witness shall file and serve a..., limitations on the parties' resources, and the importance of the issues in the case. (c) Such notice as...

  10. 7 CFR 761.209 - Loan funds for beginning farmers.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 7 2010-01-01 2010-01-01 false Loan funds for beginning farmers. 761.209 Section 761... Funds to State Offices § 761.209 Loan funds for beginning farmers. Each fiscal year, the Agency reserves a portion of direct and guaranteed FO and OL loan funds for beginning farmers in accordance...

  11. 20 CFR 209.15 - Compensation reportable when paid.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Compensation reportable when paid. 209.15... RAILROAD EMPLOYERS' REPORTS AND RESPONSIBILITIES § 209.15 Compensation reportable when paid. (a) General. In preparing a report required under this part, an employer may report compensation in the...

  12. 18 CFR 706.209 - Gambling, betting, and lotteries.

    Science.gov (United States)

    2010-04-01

    ... lotteries. 706.209 Section 706.209 Conservation of Power and Water Resources WATER RESOURCES COUNCIL..., and lotteries. An employee shall not participate, while on Government-owned or leased property or..., in conducting a lottery or pool, in a game for money or property, or in selling or purchasing...

  13. 48 CFR 2452.209-71 - Limitation on future contracts.

    Science.gov (United States)

    2010-10-01

    ... or through the performance of tasks pursuant to this contract, is required to develop specifications... contracts. 2452.209-71 Section 2452.209-71 Federal Acquisition Regulations System DEPARTMENT OF HOUSING AND URBAN DEVELOPMENT CLAUSES AND FORMS SOLICITATION PROVISIONS AND CONTRACT CLAUSES Texts of Provisions...

  14. 8 CFR 209.1 - Adjustment of status of refugees.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of status of refugees. 209.1... STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 209.1 Adjustment of status of refugees. The provisions of this section shall provide the sole and exclusive procedure for adjustment of status by a...

  15. 27 CFR 46.209 - Articles in vending machines.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 2 2010-04-01 2010-04-01 false Articles in vending machines. 46.209 Section 46.209 Alcohol, Tobacco Products and Firearms ALCOHOL AND TOBACCO TAX AND TRADE BUREAU, DEPARTMENT OF THE TREASURY (CONTINUED) TOBACCO MISCELLANEOUS REGULATIONS RELATING TO TOBACCO PRODUCTS AND CIGARETTE PAPERS AND TUBES...

  16. Radiobiological Effects of Alpha-Particles from Astatine-211: From DNA Damage to Cell Death

    Energy Technology Data Exchange (ETDEWEB)

    Claesson, Kristina

    2011-05-15

    In recent years, the use of high linear energy transfer (LET) radiation for radiotherapeutic applications has gained increased interest. Astatine-211 (211At) is an alpha-particle emitting radionuclide, promising for targeted radioimmunotherapy of isolated tumor cells and microscopic clusters. To improve development of safe radiotherapy using 211At it is important to increase our knowledge of the radiobiological effects in cells. During radiotherapy, both tumors and adjacent normal tissue will be irradiated and therefore, it is of importance to understand differences in the radio response between proliferating and resting cells. The aim of this thesis was to investigate effects in fibroblasts with different proliferation status after irradiation with alpha-particles from 211At or X-rays, from inflicted DNA damage, to cellular responses and biological consequences. Throughout this work, irradiation was performed with alpha-particles from 211A or X-rays. The induction and repair of double-strand breaks (DSBs) in human normal fibroblasts were investigated using pulsed-field gel electrophoresis and fragment analysis. The relative biological effectiveness (RBE) of 211At for DSB induction varied between 1.4 and 3.1. A small increase of DSBs was observed in cycling cells compared to stationary cells. The repair kinetics was slower after 211At and more residual damage was found after 24 h. Comparison between cells with different proliferation status showed that the repair was inefficient in cycling cells with more residual damage, regardless of radiation quality. Activation of cell cycle arrests was investigated using immunofluorescent labeling of the checkpoint kinase Chk2 and by measuring cell cycle distributions with flow cytometry analysis. After alpha-particle irradiation, the average number of Chk2-foci was larger and the cells had a more affected cell cycle progression for several weeks compared with X-irradiated cells, indicating a more powerful arrest after 211At

  17. Radiationless transition probabilities in muonic 209Bi

    International Nuclear Information System (INIS)

    The probability for non-radiative (n.r.) excitations in muonic 209Bi was determined from a (μ-, γγ)-measurement by comparing the intensities of muonic X-ray transitions in single and coincidence spectra. The values of Pn.r.(3p→1s)=(17.9±2.0)% and Pn.r.(3d→1s)=(3.0±2.2)% were measured for the first time. The strength of the n.r. decay of the 2p-level was found to be (4.2±2.2)%. The n.r. transition probabilities of two subcomplexes of the (2p→1s)-transition leading to different mean excitation energies are (3.2±1.8)% and (5.0±2.0)%, respectively. (orig.)

  18. Diverse impacts of a step and repeated BDE209-Pb exposures on accumulation and metabolism of BDE209 in earthworms.

    Science.gov (United States)

    Zhang, Wei; Liang, Jun; Li, Jing; Lin, Kuangfei; Fu, Rongbing

    2016-09-01

    Decabromodiphenyl ether (BDE209) and lead (Pb) are the two common contaminants at e-waste recycling sites (EWRSs). A laboratory incubation study was conducted to explore the impacts of a step and repeated BDE209-Pb exposures on accumulation and metabolism of BDE209 in earthworms Eisenia fetida for the first time. The results indicated that BDE209 concentrations in repetitively-polluted soils were clearly higher. And the existence of high-level Pb could promote the bioaccumulation of BDE209 in earthworms along the exposure time. The post-clitellum contents of BDE209 were more than the pre-clitellum during the entire incubation. Additionally, GC/MS analysis results demonstrated that BDE206, BDE208, BDE153, BDE99, BDE47 and BDE28 could be detected in Eisenia fetida throughout 28-d experiment, and BDE206 and BDE208 were predominant metabolic products. A step exposure decreased the capability to metabolize BDE209 in the presence of Pb. Average bioaccumulation factor (BAF) for a step treatment was 0.525, as well as it was more than 1.1 times that of repeated exposure (BAF = 0.48). SEM observations suggested that a step exposure mode aggravated the damage in earthworms than repeated exposure. The results and related findings will establish a useful scientific basis for soil ecological risk assessment at EWRSs. PMID:27295440

  19. [Survival after gastrectomy for cancer. 209 cases].

    Science.gov (United States)

    Le Treut, Y P; Capobianco, C; Botti, G; Christophe, M; Lebreuil, G; Bricot, R

    1992-09-26

    The long-term results of 209 gastrectomies performed for adenocarcinoma, including 117 which were prospectively collected, are presented. Resection was curative in 154 cases (73.6 percent). The TNM distribution of the tumours was: stage I (TxNOMO) 75 cases, stage II (TxN1MO) 46 cases, stage III (TxN2MO) 33 cases and stage IV (TxNxM1) 55 cases. Lymph node involvement was more frequent in the prospective than in the retrospective study. With a more than 5 years' follow-up of 80 percent of the patients operated upon, the actuarial survival rate at 5 years (operative mortality included) was 38 percent for all lesions, 52 percent for curative resection and 2 percent for palliative resection. Following curative resection, the survival rates for tumours of the upper, middle and lower thirds of the stomach were 40, 60 and 55 percent respectively. These rates were 60 percent for stage I tumours, 54 percent for stage II tumours and 25 percent for stage III tumours. The results obtained in this series, where most of the curative gastrectomies included excision of N1 and N2 lymph nodes, show that lymph node involvement has no significant importance for the prognosis when it is proximal (N1) and is not incompatible with prolonged survival when it is pedicular (N2). PMID:1465364

  20. A biokinetic study of {sup 209}Po in man

    Energy Technology Data Exchange (ETDEWEB)

    Henricsson, C.F.; Ranebo, Y. [Department of Medical Radiation Physics, Clinical Sciences in Lund, Lund University, Skane University Hospital in Lund (Sweden); Hansson, M. [Medical Radiation Physics, Department of Clinical Sciences in Malmoe, Lund University, Skane University Hospital in Malmoe (Sweden); Raeaef, C.L., E-mail: Christopher.Raaf@med.lu.se [Medical Radiation Physics, Department of Clinical Sciences in Malmoe, Lund University, Skane University Hospital in Malmoe (Sweden); Holm, E. [Norwegian Radiation Protection Authority, Osteras (Norway)

    2012-10-15

    Five adult volunteers participated in a biokinetic study of radioactive polonium. Portions of about 10 Bq of {sup 209}Po were orally administrated to four of the volunteers in a single ingestion. The fifth volunteer ingested a daily amount of 53 mBq of 209Po for 243 d to study the time to achieve equilibrium between intake and excretion for protracted intakes. For the subjects ingesting single intakes of {sup 209}Po complete sampling of urine and feces was subsequently collected the first few days upon the ingestion. The samples were processed with radiochemical extraction and analyzed with alpha spectrometry. In the study, the maximum daily excretion rates in feces were 18-50% of the ingested activity, observed within 3 d after intake. Regarding the urine excretion, the daily excretion peaked, on average, at 0.15-1% of the ingested activity within two days upon intake. These results indicate an average gastro-intestinal uptake fraction of 0.46 {+-} 0.08, which agrees well with earlier biokinetic studies of polonium in man. -- Highlights: Black-Right-Pointing-Pointer Human metabolism of an oral intake of polonium. Black-Right-Pointing-Pointer 4 individuals were administrated about 10 Bq polonium-209. Black-Right-Pointing-Pointer Gastro-intestinal uptake fraction, if orally administrated polonium-209 was investigated. Black-Right-Pointing-Pointer The biological half-time of polonium in human body was studied.

  1. The continuum shell-model neutron states of 209Pb

    Indian Academy of Sciences (India)

    Ramendra Nath Majumdar

    2003-12-01

    The neutron strength distributions of the three high-spin 117/2, 2ℎ11/2 and 113/2 states of 209Pb have been obtained within the formalism of the core-polarisation effect where the effect of interaction of the neutron shell-model states of 209Pb with the collective vibrational states (originating also from the giant resonances) have been taken into consideration. The theoretical results have been discussed in the light of works on 117/2, 2ℎ11/2 and 113/2 neutron orbitals of 209Pb. The shell-model energies of the neutron states have been obtained by Skyrme–Hartree–Fock method.

  2. 48 CFR 1553.209-70 - EPA Form 1900-26, Contracting Officer's Evaluation of Contractor Performance.

    Science.gov (United States)

    2010-10-01

    ..., Contracting Officer's Evaluation of Contractor Performance. 1553.209-70 Section 1553.209-70 Federal... 1553.209-70 EPA Form 1900-26, Contracting Officer's Evaluation of Contractor Performance. As prescribed... evaluation of Contractor performance....

  3. 48 CFR 3052.209-72 - Organizational conflict of interest.

    Science.gov (United States)

    2010-10-01

    ... CONTRACT CLAUSES Text of Provisions and Clauses 3052.209-72 Organizational conflict of interest. As prescribed in (HSAR) 48 CFR 3009.507-1, insert the following provision: Organizational Conflict of Interest... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Organizational conflict...

  4. 48 CFR 1552.209-76 - Contractor performance evaluations.

    Science.gov (United States)

    2010-10-01

    ... 1552.209-76 Contractor performance evaluations. As prescribed in section 1509.170-1, insert the following clause in all applicable solicitations and contracts. Contractor Performance Evaluations (OCT 2002... compliance with safety standards performance categories if deemed appropriate for the evaluation or...

  5. 48 CFR 14.209 - Cancellation of invitations before opening.

    Science.gov (United States)

    2010-10-01

    ... REGULATION CONTRACTING METHODS AND CONTRACT TYPES SEALED BIDDING Solicitation of Bids 14.209 Cancellation of... invitation is desirable. (b) When an invitation issued other than electronically is cancelled, bids that have... prospective bidders to whom invitations were issued. When an invitation issued electronically is cancelled,...

  6. 9 CFR 113.209 - Rabies Vaccine, Killed Virus.

    Science.gov (United States)

    2010-01-01

    ... 5 U.S.C. 552(a) and 1 CFR part 51. Copies may be obtained from the World Health Organization... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Rabies Vaccine, Killed Virus. 113.209... AGRICULTURE VIRUSES, SERUMS, TOXINS, AND ANALOGOUS PRODUCTS; ORGANISMS AND VECTORS STANDARD...

  7. 12 CFR 347.209 - Pledge of assets.

    Science.gov (United States)

    2010-01-01

    ... Development Bank, Asian Development Bank, Inter-American Development Bank, and the International Bank for... INTERNATIONAL BANKING Foreign Banks § 347.209 Pledge of assets. (a) Purpose. A foreign bank that has an insured... market value of such assets at the time of the original pledge and thereafter as of the last day of...

  8. 7 CFR 400.209 - Electronic transmission and receiving system.

    Science.gov (United States)

    2010-01-01

    ... Contract-Standards for Approval § 400.209 Electronic transmission and receiving system. Any Contractor under the Contract is required to: (a) Adopt a plan for the purpose of transmitting and receiving... 7 Agriculture 6 2010-01-01 2010-01-01 false Electronic transmission and receiving system....

  9. 48 CFR 3452.209-70 - Organizational conflict of interest.

    Science.gov (United States)

    2010-10-01

    ... it (_) is (_) is not aware of any potential organization conflict of interest that it may have under... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Organizational conflict of... Clauses 3452.209-70 Organizational conflict of interest. As prescribed in 3409.570, insert the...

  10. Engineering study for closure of 209E facility

    International Nuclear Information System (INIS)

    This document is an engineering study for evaluating alternatives to determine the most cost effective closure plan for the 209E Facility, Critical Mass Laboratory. This laboratory is located in the 200 East Area of the Hanford Site and contains a Critical Assembly Room and a Mix room were criticality experiments were once performed

  11. 14 CFR 1274.209 - Evaluation and selection.

    Science.gov (United States)

    2010-01-01

    ... WITH COMMERCIAL FIRMS Pre-Award Requirements § 1274.209 Evaluation and selection. (a) Factor... the competitive award of cooperative agreements to commercial entities shall include evaluation of... with. (l) Printing, binding, and duplicating. Proposals for efforts that involve printing, binding,...

  12. 40 CFR 209.2 - Use of number and gender.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Use of number and gender. 209.2... gender. In these rules of practice, words in the singular number apply to the plural and words in the masculine gender apply to the feminine and vice versa....

  13. Final Report for research grant "Development of Methods for High Specific Activity Labeling of Biomolecules Using Astatine-211 in Different Oxidation States"

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, D., Scott

    2011-12-14

    The overall objective of this research effort was to develop methods for labeling biomolecules with higher oxidation state species of At-211. This was to be done in an effort to develop reagents that had higher in vivo stability than the present carbon-bonded At-211-labeled compounds. We were unsuccessful in that effort, as none of the approaches studied provided reagents that were stable to in vivo deastatination. However, we gained a lot of information about At-211 in higher oxidation states. The studies proved to be very difficult as small changes in pH and other conditions appeared to change the nature of the species that obtained (by HPLC retention time analyses), with many of the species being unidentifiable. The fact that there are no stable isotopes of astatine, and the chemistry of the nearest halogen iodine is quite different, made it very difficult to interpret results of some experiments. With that said, we believe that a lot of valuable information was obtained from the studies. The research effort evaluated: (1) methods for chemical oxidation of At-211, (2) approaches to chelation of oxidized At-211, and (3) approaches to oxidation of astatophenyl compounds. A major hurdle that had to be surmounted to conduct the research was the development of HPLC conditions to separate and identify the various oxidized species formed. Attempts to develop conditions for separation of iodine and astatine species by normal and reversed-phase TLC and ITLC were not successful. However, we were successful in developing conditions (from a large number of attempts) to separate oxidized forms of iodine ([I-125]iodide, [I-125]iodate and [I-125]periodate) and astatine ([At-211]astatide, [At-211]astatate, [At-211]perastatate, and several unidentified At-211 species). Information on the basic oxidation and characterization of At-211 species is provided under Objective 1. Conditions were developed to obtain new At-211 labeling method where At-211 is chelated with the DOTA and

  14. 41 CFR 101-27.209 - Utilization and distribution of shelf-life items.

    Science.gov (United States)

    2010-07-01

    ... distribution of shelf-life items. 101-27.209 Section 101-27.209 Public Contracts and Property Management... PROCUREMENT 27-INVENTORY MANAGEMENT 27.2-Management of Shelf-Life Materials § 101-27.209 Utilization and distribution of shelf-life items. Where it is determined that specified quantities of both Type I and Type...

  15. 41 CFR 101-6.209-3 - Access to sources of information.

    Science.gov (United States)

    2010-07-01

    ... information. 101-6.209-3 Section 101-6.209-3 Public Contracts and Property Management Federal Property...-Nondiscrimination in Programs Receiving Federal Financial Assistance § 101-6.209-3 Access to sources of information... business hours to such of its books, records, accounts, and other sources of information, and...

  16. 8 CFR 209.2 - Adjustment of status of alien granted asylum.

    Science.gov (United States)

    2010-01-01

    ... 8 Aliens and Nationality 1 2010-01-01 2010-01-01 false Adjustment of status of alien granted asylum. 209.2 Section 209.2 Aliens and Nationality DEPARTMENT OF HOMELAND SECURITY IMMIGRATION REGULATIONS ADJUSTMENT OF STATUS OF REFUGEES AND ALIENS GRANTED ASYLUM § 209.2 Adjustment of status of...

  17. 33 CFR 209.230 - Use of reservoir areas for recreation.

    Science.gov (United States)

    2010-07-01

    ... in 36 CFR parts 311 to 326. Licenses and leases are granted under the law containing conditions and... recreation. 209.230 Section 209.230 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE ARMY, DEPARTMENT OF DEFENSE ADMINISTRATIVE PROCEDURE § 209.230 Use of reservoir areas for...

  18. Multinucleon photonuclear reactions on {sup 209}Bi: Experiment and evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Belyshev, S.S.; Kurilik, A.S. [Lomonosov Moscow State University, Department of Physics, Moscow (Russian Federation); Filipescu, D.M.; Tesileanu, O. [Extreme Light Infrastructure - Nuclear Physics/Horia Hulubei National Institute for R and D in Physics and Nuclear Engineering, Bucharest-Magurele (Romania); Gheoghe, I. [Extreme Light Infrastructure - Nuclear Physics/Horia Hulubei National Institute for R and D in Physics and Nuclear Engineering, Bucharest-Magurele (Romania); University of Bucharest, Faculty of Physics, Bucharest-Magurele (Romania); Ishkhanov, B.S. [Lomonosov Moscow State University, Department of Physics, Moscow (Russian Federation); Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University, Moscow (Russian Federation); Khankin, V.V.; Kuznetsov, A.A.; Orlin, V.N.; Peskov, N.N.; Stopani, K.A.; Varlamov, V.V. [Skobeltsyn Institute of Nuclear Physics, Lomonosov Moscow State University, Moscow (Russian Federation)

    2015-06-15

    Photon activation technique using bremsstrahlug with end-point energy 55.6 MeV is used to induce photonuclear reactions in a {sup 209}Bi target. Absolute yields and integrated cross sections of multiparticle reactions (γ, 2n-6n), (γ, 4n1p), and (γ, 5n1p) are obtained. The results are compared to predictions of statistical models using systematical and microscopic description of photoabsorption and to the result of evaluation of the partial photoneutron reaction cross sections. Based on a comparison with existing experimental photoneutron cross sections and model calculations, we make a conclusion that neutron multiplicity assignment in available photoneutron cross sections on {sup 209}Bi can be corrected and evaluated cross sections of (γ, 1n) and (γ, 2n) are obtained that are in an agreement with the obtained experimental results. (orig.)

  19. Breeding of New Maize Cultivar Danyu 209%玉米杂交种丹玉209的选育

    Institute of Scientific and Technical Information of China (English)

    陈晓旭; 岳辉; 王作英; 鲁俊田; 陈丽; 刘日尊; 左青

    2015-01-01

    丹玉209是丹东农业科学院、辽宁丹玉种业科技股份有限公司于2009年选育的中熟玉米品种。以玉米自交系 R88为母本,以自交系 L34为父本杂交组配而成的玉米杂交种,该杂交种具有高产、优质、抗倒伏、抗叶斑病和适应性广等特点。适应在辽宁省春播玉米区种植。种植密度适宜在5.25万株~6万株/ hm2。%Corn hybrid cultivar Danyu 209 was developed by Dan Dong Academy of Agricultural Sciences of Liaoning Province and Liaoning Danyu Seed Science and Technology Co. ,Ltd. Using inbred line R88 as fe-male parent and the L34 as male parent . According to the variety production test ,Danyu 209 has the charac-teristics of high yield,good quality,muli-resistance and wide adaptation. The variety is suitable for direct see-ding in spring in Liaoning province . The density of the variety was up to 52 500 plants / hm 2 ~ 60 000 plants /hm2 .

  20. Repolarization of Negative Muons by Polarized $^{209}$Bi Nuclei

    CERN Document Server

    Kadono, R; Ishikawa, T; Nishiyama, K; Nagamine, K; Yamazaki, T; Bosshard, A; Döbeli, M; van Elmbt, L; Schaad, M; Truöl, P; Bay, A; Perroud, J P; Deutsch, J; Tasiaux, B; Hagn, E

    2016-01-01

    A large $\\mu^-$ polarization was achieved in muonic Bi atoms with the help of the strong hyperfine field in a polarized nuclear target. Using $^{209}$Bi nuclei polarized to ($59\\pm9$)% in ferromagnetic BiMn, we observed a $\\mu$-$e$ decay asymmetry of ($13.1\\pm3.9$)%, which gives $\\mu^-$ polarization per nuclear polarization equal to $-1.07\\pm 0.35$. This value is almost consistent with $-0.792$ calculated for nuclei with spin $I= \\frac{9}{2}$ and a positive magnetic moment under the assumption that the hyperfine interaction becomes effective in the lowest muonic states.

  1. Toxic effects of decabromodiphenyl ether (BDE-209 on human embryonic kidney cells

    Directory of Open Access Journals (Sweden)

    Min eLi

    2014-05-01

    Full Text Available Polybrominated diphenyl ethers (PBDEs are widely used as flame-retardant additives in consumer and household products and can escape into the environment over time. PBDEs have become a global environmental organic pollutant due to the properties of persistence, toxicity, and bioaccumulation. The well-studied toxic effects of PBDEs mainly include thyroid hormone disruption and neurotoxicity. There is no consistent conclusions on the carcinogenic potential of PBDEs to date. Here, we explored the toxic effects of BDE-209 on human embryonic kidney cells (HEK293T. The comparison of the gene expression profiles of HEK293T cells with BDE-209 treatment and the negative control found that BDE-209 exposure may alter nucleosome organization through significantly changing the expression of histone gene clusters. The remodeled chromatin structure could further disturb systemic lupus erythematosus as one of the toxic effects of BDE-209. Additionally, gene sets of different cancer modules are positively correlated with BDE-209 exposure. This suggests that BDE-209 has carcinogenic potential for a variety of tumors. Collectively, BDE-209 has a broader toxicity not limited to disruption of thyroid hormone-related biological processes. Notably, the toxic effects of BDE-209 dissolved in dimethyl sulfoxide (DMSO is not the simply additive effects of BDE-209 and DMSO alone.

  2. Galaxy Evolution in the Environment of ABCG 209

    CERN Document Server

    Haines, C P; Merluzzi, P; La Barbera, F; Massarotti, M; Busarello, G; Girardi, M

    2004-01-01

    We examine the environmental effects on the photometric properties of galaxies for the rich galaxy cluster ABCG 209 at z=0.209. We use archive CFHT optical imaging of a 42'x28' field centred on the cluster to produce a galaxy sample complete to B=25.0 and R=24.5. Both the composite and red sequence galaxy luminosity functions are found to be dependent on the local galaxy surface density, their faint-end slopes becoming shallower with increasing density. We explain this as a combination of the morphology-density relation, and dwarf galaxies being cannibalised and/or disrupted by the cD galaxy and the ICM in the cluster core. The B-R colour of the red sequence itself appears 0.02mag redder for the highest-density regions, indicative of their stellar populations being marginally (<5%) older or (<20%) more metal-rich. This may be due to the galaxies themselves forming earliest in the rarest overdensities marked by rich clusters, or their star-formation being suppressed earliest by the ICM.

  3. New measurement of neutron capture resonances of 209Bi

    CERN Document Server

    Domingo-Pardo, C; Abbondanno, U; Aerts, G; Alvarez-Pol, H; Alvarez-Velarde, F; Andriamonje, Samuel A; Andrzejewski, J; Assimakopoulos, Panayiotis; Audouin, L; Badurek, G; Baumann, P; Becvar, F; Berthoumieux, E; Calviño, F; Cano-Ott, D; Capote, R; Carrillode Albornoz, A; Cennini, P; Chepel, V; Chiaveri, Enrico; Colonna, N; Cortés, G; Couture, A; Cox, J; Dahlfors, M; David, S; Dillman, I; Dolfini, R; Dridi, W; Durán, I; Eleftheriadis, C; Embid-Segura, M; Ferrant, L; Ferrari, A; Ferreira-Marques, R; Fitzpatrick, L; Frais-Kölbl, H; Fujii, K; Furman, W; Gallino, R; Gonçalves, I; Gonzalez-Romero, E; Goverdovski, A; Gramegna, F; Griesmayer, E; Guerrero, C; Gunsing, F; Haas, B; Haight, R; Heil, M; Herrera-Martínez, A; Igashira, M; Isaev, S; Jericha, E; Kadi, Y; Kappeler, F; Karamanis, D; Karadimos, D; Kerveno, M; Ketlerov, V; Köhler, P; Konovalov, V; Kossionides, E; Krticka, M; Lamboudis, C; Leeb, H; Lindote, A; Lopes, I; Lozano, M; Lukic, S; Marganiec, J; Marques, L; Marrone, S; Mastinu, P; Mengoni, A; Milazzo, P M; Moreau, C; Mosconi, M; Neves, F; Oberhummer, Heinz; Oshima, M; O'Brien, S; Pancin, J; Papachristodoulou, C; Papadopoulos, C; Paradela, C; Patronis, N; Pavlik, A; Pavlopoulos, P; Perrot, L; Plag, R; Plompen, A; Plukis, A; Poch, A; Pretel, C; Quesada, J; Rauscher, T; Reifarth, R; Rosetti, M; Rubbia, Carlo; Rudolf, G; Rullhusen, P; Salgado, J; Sarchiapone, L; Savvidis, I; Stéphan, C; Tagliente, G; Taín, J L; Tassan-Got, L; Tavora, L; Terlizzi, R; Vannini, G; Vaz, P; Ventura, A; Villamarín, D; Vincente, M C; Vlachoudis, V; Vlastou, R; Voss, F; Walter, S; Wendler, H; Wiescher, M; Wisshak, K

    2006-01-01

    The neutron capture cross section of Bi209 has been measured at the CERN n TOF facility by employing the pulse-height-weighting technique. Improvements over previous measurements are mainly because of an optimized detection system, which led to a practically negligible neutron sensitivity. Additional experimental sources of systematic error, such as the electronic threshold in the detectors, summing of gamma-rays, internal electron conversion, and the isomeric state in bismuth, have been taken into account. Gamma-ray absorption effects inside the sample have been corrected by employing a nonpolynomial weighting function. Because Bi209 is the last stable isotope in the reaction path of the stellar s-process, the Maxwellian averaged capture cross section is important for the recycling of the reaction flow by alpha-decays. In the relevant stellar range of thermal energies between kT=5 and 8 keV our new capture rate is about 16% higher than the presently accepted value used for nucleosynthesis calculations. At th...

  4. The internal barriers of rotation for the 209 polychlorinated biphenyls.

    Science.gov (United States)

    Andersson, P L; Haglund, P; Tysklind, M

    1997-01-01

    The internal barrier of rotation (Erot) was calculated for all 209 polychlorinated biphenyls (PCBs) by using a semi-empirical method, viz. the Austin Model 1 (AMI) Hamiltonian. The difference in total energy between a forced planar state and an optimised twisted structure was defined as Erot. The Erot values were in the range of 8.33 to 483 kJ/mol, and were significantly influenced by the number of chlorine atoms in ortho position. An additional structural characteristic of the PCBs influencing Erot of ortho substituted congeners was substitution by chlorine atoms in vicinal meta positions, which is assumed to prevent outward bending of ortho substituents. This so-called buttressing effect contributed with 4 to 31 kJ/mol per added chlorine atom. In conclusion, the internal barrier of rotation, calculated for all 209 PCBs, provides an important structure dependent physico-chemical parameter for multivariate modelling of future quantitative structure-activity and structure-property relationships (QSARs/QSPRs). PMID:19005788

  5. 31 CFR 560.209 - Prohibited transactions with respect to the development of Iranian petroleum resources.

    Science.gov (United States)

    2010-07-01

    ... to the development of Iranian petroleum resources. 560.209 Section 560.209 Money and Finance... respect to the development of Iranian petroleum resources. Except as otherwise authorized, and... development of petroleum resources located in Iran, or (2) A guaranty of another person's performance...

  6. The Effects of Proposition 209 on California: Higher Education, Public Employment, and Contracting

    Science.gov (United States)

    Geshekter, Charles L.

    2008-01-01

    In 1996, Californians overwhelmingly approved Proposition 209, which prohibited all state agencies from discriminating on the basis of race, ethnicity, or gender in university admissions, public employment, or competition for a state contract. Opponents of Proposition 209 predicted dire consequences for California's ethnic minorities and women if…

  7. 33 CFR 209.320 - Policy on release of commercial statistics.

    Science.gov (United States)

    2010-07-01

    ... statistics. 209.320 Section 209.320 Navigation and Navigable Waters CORPS OF ENGINEERS, DEPARTMENT OF THE... statistics. The collection of commercial statistics pertaining to rivers, harbors, and waterways, and annual... waterway statistics. In case Federal or State agencies or local interests request other than...

  8. 48 CFR 1552.209-73 - Notification of conflicts of interest regarding personnel.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Notification of conflicts of interest regarding personnel. 1552.209-73 Section 1552.209-73 Federal Acquisition Regulations... guard services, or electrical services, provisions which shall conform substantially to the language...

  9. 20 CFR 209.14 - Report of separation allowances subject to tier II taxation.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Report of separation allowances subject to tier II taxation. 209.14 Section 209.14 Employees' Benefits RAILROAD RETIREMENT BOARD REGULATIONS UNDER... separation allowances subject to tier II taxation. For any employee who is paid a separation payment,...

  10. Study of rare processes induced by 209-Gev muons

    International Nuclear Information System (INIS)

    Analysis of dimuon final states from 1.4 x 1011 positive and 2.9 x 1010 negative 209-Gev muons in a magnetized iron calorimeter has set a lower limit of 9 Gev/c2 on the mass of a heavy neutral muon (M0), and a 90%-confidence level upper limit of sigma(μN→b anti bX)B(b anti b→μX)-36 cm2 for the production of bottom hadrons by muons. The dimuon mass spectrum from 102,678 trimuon final states places a 90%-confidence level upper limit for the muoproduction of upsilon states: sigma(μN→μ UPSILON X)B(UPSILON→μ+μ-)-39 cm2. In addition, analysis of 71 rare multimuon events, including 4- and 5-muon final states, is presented

  11. 48 CFR 252.209-7001 - Disclosure of ownership or control by the government of a terrorist country.

    Science.gov (United States)

    2010-10-01

    ... control by the government of a terrorist country. 252.209-7001 Section 252.209-7001 Federal Acquisition... ownership or control by the government of a terrorist country. As prescribed in 209.104-70(a), use the following provision: Disclosure of Ownership or Control by the Government of a Terrorist Country (JAN...

  12. 43 CFR 17.209 - Effect of State or local law or other requirements and effect of employment opportunities.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Effect of State or local law or other requirements and effect of employment opportunities. 17.209 Section 17.209 Public Lands: Interior Office of the... Nondiscrimination on the Basis of Handicap § 17.209 Effect of State or local law or other requirements and effect...

  13. Weak Lensing Mass Reconstruction of the Galaxy Cluster Abell 209

    CERN Document Server

    Paulin-Henriksson, S; Haines, C P; Radovich, M; Mercurio, A; Becciani, U

    2007-01-01

    Weak lensing applied to deep optical images of clusters of galaxies provides a powerful tool to reconstruct the distribution of the gravitating mass associated to these structures. We use the shear signal extracted by an analysis of deep exposures of a region centered around the galaxy cluster Abell 209, at redshift z=0.2, to derive both a map of the projected mass distribution and an estimate of the total mass within a characteristic radius. We use a series of deep archival R-band images from CFHT-12k, covering an area of 0.3 deg^2. We determine the shear of background galaxy images using a new implementation of the modified Kaiser-Squires-Broadhurst pipeline for shear determination, which we has been tested against the ``Shear TEsting Program 1 and 2'' simulations. We use mass aperture statistics to produce maps of the 2 dimensional density distribution, and parametric fits using both Navarro-Frenk-White (NFW) and singular-isothermal-sphere profiles to constrain the total mass. The projected mass distributi...

  14. Biodegradation of Decabromodiphenyl Ether (BDE-209 by Crude Enzyme Extract from Pseudomonas aeruginosa

    Directory of Open Access Journals (Sweden)

    Yu Liu

    2015-09-01

    Full Text Available The biodegradation effect and mechanism of decabromodiphenyl ether (BDE-209 by crude enzyme extract from Pseudomonas aeruginosa were investigated. The results demonstrated that crude enzyme extract exhibited obviously higher degradation efficiency and shorter biodegradation time than Pseudomonas aeruginosa itself. Under the optimum conditions of pH 9.0, 35 °C and protein content of 2000 mg/L, 92.77% of the initial BDE-209 (20 mg/L was degraded after 5 h. A BDE-209 biodegradation pathway was proposed on the basis of the biodegradation products identified by GC-MS analysis. The biodegradation mechanism showed that crude enzyme extract degraded BDE-209 into lower brominated PBDEs and OH-PBDEs through debromination and hydroxylation of the aromatic rings.

  15. 49 CFR 180.209 - Requirements for requalification of specification cylinders.

    Science.gov (United States)

    2010-10-01

    ... CONTINUING QUALIFICATION AND MAINTENANCE OF PACKAGINGS Qualification, Maintenance and Use of Cylinders § 180... incorporated into § 180.209 because of the inaccurate amendatory instruction. For the convenience of the...

  16. Feasibility study on polonium-209 as radioisotope fuel for space nuclear power

    International Nuclear Information System (INIS)

    We have investigated the performance and the production method of alternative isotopes of 238Pu as a radioisotope fuel for use in space radioisotope power generators. Polonium-209 has the possibility to be an alternative material of 238Pu. It has enough half-time of 102 years and the specific power of 490 W/kg. From the simulation, the beam current of 14 A with 40 MeV proton energy provides 1 kg/yr of 209Po annually. (author)

  17. Effect of cadmium ion on biodegradation of decabromodiphenyl ether (BDE-209) by Pseudomonas aeruginosa

    International Nuclear Information System (INIS)

    Highlights: • BDE-209 degradation by P. aeruginosa in the presence of Cd was investigated. • Degradation was accelerated by the increase of CSH induced by low level of Cd. • Higher membrane permeability caused by low level of Cd promoted degradation. • Depression of cell growth and metabolism by high content Cd inhibited degradation. -- Abstract: The influence of Cd(II) ions on the degradation of decabromodiphenyl ether (BDE-209) by an aerobic degrading strain, Pseudomonas aeruginosa, was investigated. The results demonstrated that the strain P. aeruginosa exhibited a high level of resistance against cadmium toxicity, and Cd(II) ions of different concentrations possessed mixed reactions on BDE-209 bioremoval. The degradation efficiency was stimulated at low concentrations of Cd(II) ions (≤1 mg L−1) but inhibited at higher levels (≥5 mg L−1). Subsequent analyses revealed that the increase of cell hydrophobicity and membrane permeability were two main factors for Cd(II) ions of low concentrations to accelerate BDE-209 degradation. However, inhibition effect by high concentrations of Cd(II) ions was mainly attributed to the negative impact of metals on growth and metabolism of the strain. It was also showed through cellular distribution of BDE-209 that different concentration of Cd(II) ions affected the amount of BDE-209 inside or outside the cell at different incubation time

  18. Effect of cadmium ion on biodegradation of decabromodiphenyl ether (BDE-209) by Pseudomonas aeruginosa

    Energy Technology Data Exchange (ETDEWEB)

    Shi, Guangyu [State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Science, Guangzhou 510640 (China); Yin, Hua, E-mail: huayin@scut.edu.cn [Key Laboratory of Pollution Control and Ecosystem Restoration in Industry Clusters, Ministry of Education, College of Environment and Energy, South China University of Technology, Guangzhou 510006 (China); Ye, Jinshao [Department of Environmental Engineering, Jinan University, Guangzhou 510632 (China); Peng, Hui [Department of Chemistry, Jinan University, Guangzhou 510632 (China); Li, Jun; Luo, Chunling [State Key Laboratory of Organic Geochemistry, Guangzhou Institute of Geochemistry, Chinese Academy of Science, Guangzhou 510640 (China)

    2013-12-15

    Highlights: • BDE-209 degradation by P. aeruginosa in the presence of Cd was investigated. • Degradation was accelerated by the increase of CSH induced by low level of Cd. • Higher membrane permeability caused by low level of Cd promoted degradation. • Depression of cell growth and metabolism by high content Cd inhibited degradation. -- Abstract: The influence of Cd(II) ions on the degradation of decabromodiphenyl ether (BDE-209) by an aerobic degrading strain, Pseudomonas aeruginosa, was investigated. The results demonstrated that the strain P. aeruginosa exhibited a high level of resistance against cadmium toxicity, and Cd(II) ions of different concentrations possessed mixed reactions on BDE-209 bioremoval. The degradation efficiency was stimulated at low concentrations of Cd(II) ions (≤1 mg L{sup −1}) but inhibited at higher levels (≥5 mg L{sup −1}). Subsequent analyses revealed that the increase of cell hydrophobicity and membrane permeability were two main factors for Cd(II) ions of low concentrations to accelerate BDE-209 degradation. However, inhibition effect by high concentrations of Cd(II) ions was mainly attributed to the negative impact of metals on growth and metabolism of the strain. It was also showed through cellular distribution of BDE-209 that different concentration of Cd(II) ions affected the amount of BDE-209 inside or outside the cell at different incubation time.

  19. CLASH-VLT: Environment-driven evolution of galaxies in the z=0.209 cluster Abell 209

    CERN Document Server

    Annunziatella, M; Biviano, A; Girardi, M; Nonino, M; Balestra, I; Rosati, P; Caminha, G Bartosch; Brescia, M; Gobat, R; Grillo, C; Lombardi, M; Sartoris, B; De Lucia, G; Demarco, R; Frye, B; Fritz, A; Moustakas, J; Scodeggio, M; Kuchner, U; Maier, C; Ziegler, B

    2016-01-01

    The analysis of galaxy properties and the relations among them and the environment, can be used to investigate the physical processes driving galaxy evolution. We study the cluster A209 by using the CLASH-VLT spectroscopic data combined with Subaru photometry, yielding to 1916 cluster members down to a stellar mass of 10^{8.6} Msun. We determine: i) the stellar mass function of star-forming and passive galaxies; ii) the intra-cluster light and its properties; iii) the orbits of low- and high-mass passive galaxies; and iv) the mass-size relation of ETGs. The stellar mass function of the star-forming galaxies does not depend on the environment, while the slope found for passive galaxies becomes flatter in the densest region. The color distribution of the intra-cluster light is consistent with the color of passive members. The analysis of the dynamical orbits shows that low-mass passive galaxies have tangential orbits, avoiding small pericenters around the BCG. The mass-size relation of low-mass passive ETGs is ...

  20. Behavior of decabromodiphenyl ether (BDE-209) in soil: Effects of rhizosphere and mycorrhizal colonization of ryegrass roots

    International Nuclear Information System (INIS)

    A rhizobox experiment was conducted to investigate degradation of decabromodiphenyl ether (BDE-209) in the rhizosphere of ryegrass and the influence of root colonization with an arbuscular mycorrhizal (AM) fungus. BDE-209 dissipation in soil varied with its proximity to the roots and was enhanced by AM inoculation. A negative correlation (P 2 = 0.66) was found between the residual BDE-209 concentration in soil and soil microbial biomass estimated as the total phospholipid fatty acids, suggesting a contribution of microbial degradation to BDE-209 dissipation. Twelve and twenty-four lower brominated PBDEs were detected in soil and plant samples, respectively, with a higher proportion of di- through hepta-BDE congeners in the plant tissues than in the soils, indicating the occurrence of BDE-209 debromination in the soil-plant system. AM inoculation increased the levels of lower brominated PBDEs in ryegrass. These results provide important information about the behavior of BDE-209 in the soil-plant system. - Research highlights: → BDE-209 dissipation in soil was affected by the proximity to the roots. → Microbial degradation contributes greatly to BDE-209 dissipation in the soil. → Twelve and twenty-four lower brominated PBDEs were detected in soil and plant samples. → AM inoculation increased root uptake and accumulation of BDE-209. - BDE-209 dissipation and degradation in soil were affected by both its proximity to ryegrass roots and inoculation with an AM fungus.

  1. Designing of Anti Dengue Drug Molecule against Insilico Modeled Target DC-Sign (CD-209

    Directory of Open Access Journals (Sweden)

    Prashantha C.N

    2013-09-01

    Full Text Available The C-type lectin DC-SIGN (CD209 plays a major role in receptor on human dendritic cells, it binds to several glycoproteins of viruses that facilitate disease progression. In dengue fever, the disease targets of arbovirus infection, show dendritic and reticuloendothelial cells that may affect immune system. The phytochemical extracts of Bosenbergia rotunda (BR have been effectively used as potential small molecular inhibitors to inhibit DC-SIGN (CD209 function. Using rational drug designing the training sets include Panduratin-A and 4-hydroxypanduratin is designed from BR derivatives could be an effective inhibitor of a DC-SIGN (CD209 binding towards the drug discovery/ therapy against dengue fever.

  2. High-energy neutron-induced fission cross sections of natural lead and bismuth-209

    OpenAIRE

    Calviño Tavares, Francisco; Cortés Rossell, Guillem Pere; Poch Parés, Agustí; Pretel Sánchez, Carme

    2011-01-01

    The CERN Neutron Time-Of-Flight (n TOF) facility is well suited to measure small neutron- induced ssion cross sections, as those of subactinides. The cross section ratios of natPb and 209Bi relative to 235U and 238U were measured using PPAC detectors. The fragment coincidence method allows to unambiguously identify the ssion events. The present experiment provides the rst results for neutron-induced ssion up to 1 GeV for natPb and 209Bi. A good agreement with previous exper...

  3. 48 CFR 1553.209-71 - EPA Form 1900-27, Project Officer's Evaluation of Contractor Performance.

    Science.gov (United States)

    2010-10-01

    ... Officer's Evaluation of Contractor Performance. 1553.209-71 Section 1553.209-71 Federal Acquisition... EPA Form 1900-27, Project Officer's Evaluation of Contractor Performance. As prescribed in 1509.170-4(a), EPA Form 1900-27 shall be used by the Project Officer to record his/her evaluation of...

  4. 40 CFR 600.209-08 - Calculation of vehicle-specific 5-cycle fuel economy values for a model type.

    Science.gov (United States)

    2010-07-01

    ...-cycle fuel economy values for a model type. 600.209-08 Section 600.209-08 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) ENERGY POLICY FUEL ECONOMY AND CARBON-RELATED EXHAUST EMISSIONS OF MOTOR VEHICLES Fuel Economy Regulations for 1977 and Later Model Year Automobiles-Procedures...

  5. Impact of co-exposure with lead and decabromodiphenyl ether (BDE-209) on thyroid function in zebrafish larvae

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Biran; Wang, Qiangwei; Wang, Xianfeng [State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072 (China); University of Chinese Academy of Sciences, Beijing 100049 (China); Zhou, Bingsheng, E-mail: bszhou@ihb.ac.cn [State Key Laboratory of Freshwater Ecology and Biotechnology, Institute of Hydrobiology, Chinese Academy of Sciences, Wuhan 430072 (China)

    2014-12-15

    Highlights: • PBDEs and metals are the main contaminants at e-waste recycling sites. • Combined effects of Pb/BDE-209 on thyroid function in zebrafish larvae were studied. • Co-exposure of Pb and BDE-209 elicited synergistic effects on T{sub 3} and T{sub 4} levels. • BDE-209 enhanced Pb uptake, and Pb decreased bioconcentration/metabolism of BDE-209. • Mixtures of Pb and BDE-209 probably result in an increase in toxicological effects. - Abstract: Polybrominated diphenyl ethers (PBDEs) and metals are the main contaminants at waste electrical and electronic equipment (“e-waste”) recycling sites. However, the potential environmental health effects of mixtures of PBDEs and metals are not known. We investigated co-exposure of lead (Pb) with decabromodiphenyl ether (BDE-209) on thyroid function in zebrafish larvae. Seven groups of embryos/larvae of zebrafish were treated with Pb (0, 2, 5, 10, 15, 20, and 30 μg/L), six groups were exposed to BDE-209 (0, 50, 100, 200, 400, and 800 μg/L), and nine groups of zebrafish larvae were treated with Pb and BDE-209 (5, 10, and 20 μg/L Pb; 50, 100, and 200 μg/L BDE-209). Embryos/larvae were exposed from 2 h post-fertilization (hpf) until 144 hpf, and thyroid hormone (TH) content measured. Pb exposure significantly decreased whole-body TH contents (triiodothyroxine (T{sub 3}) and thyroxine (T{sub 4})) but BDE-209 exposure significantly increased T{sub 3} and T{sub 4} levels. Pb or BDE-209 treatment alone caused a predicted downregulation of TH transport (i.e., expression of the mRNA or proteins of transthyretin). Chemical analyses showed Pb uptake to be increased by BDE-209, but BDE-209 bioconcentration was decreased and the ability to metabolize BDE-209 was reduced in the presence of Pb. We also found that a mixture of the two chemicals had a synergistic effect on TH levels in zebrafish.

  6. 20 CFR 209.17 - Use of payroll records as returns of compensation.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 1 2010-04-01 2010-04-01 false Use of payroll records as returns of... RAILROAD RETIREMENT ACT RAILROAD EMPLOYERS' REPORTS AND RESPONSIBILITIES § 209.17 Use of payroll records as returns of compensation. Payroll records of employers which have permanently ceased operations may...

  7. 7 CFR 1486.209 - How are program applications evaluated and approved?

    Science.gov (United States)

    2010-01-01

    ... MARKETS PROGRAM Eligibility, Applications, and Funding § 1486.209 How are program applications evaluated... or new uses. Examples include food service development, market research on potential for consumer... foreign governments collect and use market information and develop free trade policies that...

  8. Pion-Induced Fission of 209Bi and 119Sn:. Measurements, Calculations, Analyses and Comparison

    Science.gov (United States)

    Rana, Mukhtar Ahmed; Sher, Gul; Manzoor, Shahid; Shehzad, M. I.

    Cross-sections for the π--induced fission of 209Bi and 119Sn have been measured using the most sensitive CR-39 solid-state nuclear track detector. In experiments, target-detector stacks were exposed to negative pions of energy 500, 672, 1068, and 1665 MeV at the Brookhaven National Laboratory, USA. An important aspect of the present paper is the comparison of pion-induced fission fragment spectra of above mentioned nuclei with the spontaneous fission fragment spectra of 252Cf. This comparison is made in terms of fission fragment track lengths in the CR-39 detectors. Measurement results are compared with calculations of Monte Carlo and statistical weight functions methods using the computer code CEM95. Agreement between measurements and calculations is fairly good for 209Bi target nuclei whereas it is indigent for the case of 119Sn. The possibilities of the trustworthy calculations, using the computer code CEM95, comparable with measurements of pion-induced fission in intermediate and heavy nuclei are explored by employing various systematics available in the code. Energy dependence of pion-induced fission in 119Sn and 209Bi is analyzed employing a newly defined parameter geometric-size-normalized fission cross-section (χfg). It is found that the collective nuclear excitations, which may lead to fission, become more probable for both 209Bi and 119Sn nuclei with increasing energy of negative pions from 500 to 1665 MeV.

  9. Effect of copper on in vivo fate of BDE-209 in pumpkin.

    Science.gov (United States)

    Lu, Mang; Zhang, Zhong-Zhi; Su, Xiao-Li; Xu, Yu-Xin; Wu, Xue-Jiao; Zhang, Min

    2013-11-15

    A 60-day growth chamber experiments were performed to investigate the effect of Cu stress on the uptake, translocation and metabolism of decabromodiphenyl ether (BDE-209) by pumpkin. A total of nine debrominated metabolites (de-PBDEs), two hydroxylated PBDEs (OH-PBDEs) and one methoxylated PBDEs (MeO-PBDEs) were detected in the tested plants. Concentrations of the total debrominated, hydroxylated or methoxylated metabolites generally followed the order of roots>stems>leaves, and de-PBDEs>OH-PBDEs>MeO-PBDEs. These results indicate that metabolism occurred preferentially in roots than in stems and leaves. The addition of moderate dosage of Cu (50mg/kg) resulted in increment in OH-PBDE concentrations in plant tissues, whereas higher concentrations of Cu could inhibit uptake and metabolism of BDE-209. No in vivo mineralization of BDE-209 was detected in the plants. These results provide valuable information about the behavior of BDE-209 in plant tissues under heavy metal exposure. PMID:24045004

  10. 49 CFR 238.209 - Forward end structure of locomotives, including cab cars and MU locomotives.

    Science.gov (United States)

    2010-10-01

    ... 49 Transportation 4 2010-10-01 2010-10-01 false Forward end structure of locomotives, including... SAFETY STANDARDS Specific Requirements for Tier I Passenger Equipment § 238.209 Forward end structure of locomotives, including cab cars and MU locomotives. (a)(1) The skin covering the forward-facing end of...

  11. 18 CFR 1304.209 - Land-based structures/alterations.

    Science.gov (United States)

    2010-04-01

    ... 18 Conservation of Power and Water Resources 2 2010-04-01 2010-04-01 false Land-based structures... APPROVAL OF CONSTRUCTION IN THE TENNESSEE RIVER SYSTEM AND REGULATION OF STRUCTURES AND OTHER ALTERATIONS TVA-Owned Residential Access Shoreland § 1304.209 Land-based structures/alterations. (a) Except...

  12. The LEP 2 machine : pushing to the limits 209 GeV! Exhibition LEPFest 2000

    CERN Multimedia

    2000-01-01

    By installing 288 new superconducting accelerating cavities after 1995,and thanks to the excellent work of the CERN teams,energies up to 209 GeV -well beyond LEP 's original design energy -have been achieved.Significant experi- mental data have been collected at energies in excess of 206 GeV.

  13. Confirmation of 20% error in the 209Po half-life

    International Nuclear Information System (INIS)

    First results of a half-life measurement of 209Po show 20% discrepancy with the formerly recommended value of 102 (5) years, which was based on a single experiment performed in 1956. After one year of measurement, a statistical uncertainty on T1/2 of 3.5% has been reached and effects of long-term instability are assumed to be less than 5%. The preliminary half-life value obtained in this work, 120 (6) years, supports the newly determined value of 125.2 (33) years by Collé et al. (2014). The 20% error in the half-life has an impact on numerous measurements in which aged 209Po solutions were used as a tracer. - Highlights: • Measured half-life of 209Po is 120 (6) a. • The formerly recommended value was in error by 20%. • Measurement results using 209Po as a tracer are affected. • The error persisted for half a century

  14. Equal Opportunity in Higher Education: The Past and Future of California's Proposition 209

    Science.gov (United States)

    Grodsky, Eric, Ed.; Kurlaender, Michal, Ed.

    2010-01-01

    This timely book examines issues pertaining to equal opportunity--affirmative action, challenges to it, and alternatives for improving opportunities for underrepresented groups--in higher education today. Its starting point is California's Proposition 209, which ended race-based affirmative action in public education and the workplace in 1996. The…

  15. 7 CFR 1710.209 - Approval requirements for load forecast work plans.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 11 2010-01-01 2010-01-01 false Approval requirements for load forecast work plans... LOANS AND GUARANTEES Load Forecasts § 1710.209 Approval requirements for load forecast work plans. (a... utility plant of $500 million or more must maintain an approved load forecast work plan. RUS...

  16. 48 CFR 252.209-7004 - Subcontracting with firms that are owned or controlled by the government of a terrorist country.

    Science.gov (United States)

    2010-10-01

    ... that are owned or controlled by the government of a terrorist country. 252.209-7004 Section 252.209....209-7004 Subcontracting with firms that are owned or controlled by the government of a terrorist... Controlled by the Government of a Terrorist County (DEC 2006) (a) Unless the Government determines that...

  17. 25 CFR 20.209 - Can a tribe operating under a tribal redesign plan go back to operating under this part?

    Science.gov (United States)

    2010-04-01

    ... 25 Indians 1 2010-04-01 2010-04-01 false Can a tribe operating under a tribal redesign plan go back to operating under this part? 20.209 Section 20.209 Indians BUREAU OF INDIAN AFFAIRS, DEPARTMENT....209 Can a tribe operating under a tribal redesign plan go back to operating under this part? Yes,...

  18. Accumulation, tissue-specific distribution and debromination of decabromodiphenyl ether (BDE 209) in European starlings (Sturnus vulgaris)

    Energy Technology Data Exchange (ETDEWEB)

    Steen, E. van den [Department of Biology, University of Antwerp (Campus Drie Eiken), Universiteitsplein 1, 2610 Wilrijk (Belgium)]. E-mail: evi.vandensteen@ua.ac.be; Covaci, A. [Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk (Belgium); Jaspers, V.L.B. [Department of Biology, University of Antwerp (Campus Drie Eiken), Universiteitsplein 1, 2610 Wilrijk (Belgium); Dauwe, T. [Department of Biology, University of Antwerp (Campus Drie Eiken), Universiteitsplein 1, 2610 Wilrijk (Belgium); Voorspoels, S. [Toxicological Centre, University of Antwerp, Universiteitsplein 1, 2610 Wilrijk (Belgium); Eens, M. [Department of Biology, University of Antwerp (Campus Drie Eiken), Universiteitsplein 1, 2610 Wilrijk (Belgium); Pinxten, R. [Department of Biology, University of Antwerp (Campus Drie Eiken), Universiteitsplein 1, 2610 Wilrijk (Belgium)

    2007-07-15

    In this study we investigated the accumulation, tissue-specific distribution and possible debromination of BDE 209 in a terrestrial songbird species, the European starling, using silastic implants as a method of exposure. BDE 209 accumulated in the blood of the exposed starlings to a mean peak concentration of 16 {+-} 4.1 ng/ml on day 10. After this peak, there was a decline to 3.3 {+-} 0.4 ng/ml blood at the end of the exposure period of 76 days, which suggests elimination of BDE 209. In the exposed group, the muscle concentrations (461 ng/g lipid weight [lw], 430 ng/g lw) were about twofold those in liver (269 ng/g lw, 237 ng/g lw). In addition to BDE 209, other PBDE congeners, particularly octa- and nonaBDEs, were also present in the muscle and liver, suggesting bioformation from BDE 209. To our knowledge, these results are the first indications for the debromination of BDE 209 in birds. - BDE 209 accumulates in the blood and tissues of a terrestrial bird species, the European starling, and can be debrominated to lower PBDE congeners.

  19. 分化型甲状腺癌209例临床分析

    Institute of Scientific and Technical Information of China (English)

    于炳旗; 齐娟

    2008-01-01

    对我院收治的209例分化型甲状腺癌(DTC)患者的临床资料进行回顾性分析,以探讨影响DTC长期预后及复发的因素.发现209例DTC患者的复发率为18.7%,其5、10 a生存率分别为93.3%、86.4%;多因素分析表明,年龄、浸润程度、远处转移、临床病理分期是影响DTC预后的独立因素.认为年龄、浸润程度、远处转移、临床病理分期是影响DTC长期预后及复发的重要因素.

  20. High-energy Neutron-induced Fission Cross Sections of Natural Lead and Bismuth-209

    CERN Document Server

    Tarrio, D; Carrapico, C; Eleftheriadis, C; Leeb, H; Calvino, F; Herrera-Martinez, A; Savvidis, I; Vlachoudis, V; Haas, B; Koehler, P; Vannini, G; Oshima, M; Le Naour, C; Gramegna, F; Wiescher, M; Pigni, M T; Audouin, L; Mengoni, A; Quesada, J; Becvar, F; Plag, R; Cennini, P; Mosconi, M; Rauscher, T; Couture, A; Capote, R; Sarchiapone, L; Vlastou, R; Domingo-Pardo, C; Dillmann, I; Pavlopoulos, P; Karamanis, D; Krticka, M; Jericha, E; Ferrari, A; Martinez, T; Trubert, D; Oberhummer, H; Karadimos, D; Plompen, A; Isaev, S; Terlizzi, R; Cortes, G; Cox, J; Cano-Ott, D; Pretel, C; Colonna, N; Berthoumieux, E; Vaz, P; Heil, M; Lopes, I; Lampoudis, C; Walter, S; Calviani, M; Gonzalez-Romero, E; Embid-Segura, M; Stephan, C; Igashira, M; Papachristodoulou, C; Aerts, G; Tavora, L; Berthier, B; Rudolf, G; Andrzejewski, J; Villamarin, D; Ferreira-Marques, R; Tain, J L; O'Brien, S; Reifarth, R; Kadi, Y; Neves, F; Poch, A; Kerveno, M; Rubbia, C; Lazano, M; Dahlfors, M; Wisshak, K; Salgado, J; Dridi, W; Ventura, A; Andriamonje, S; Assimakopoulos, P; Santos, C; Voss, F; Ferrant, L; Patronis, N; Chiaveri, E; Guerrero, C; Perrot, L; Vicente, M C; Lindote, A; Praena, J; Baumann, P; Kappeler, F; Rullhusen, P; Furman, W; David, S; Marrone, S; Tassan-Got, L; Gunsig, F; Alvarez-Velarde, F; Massimi, C; Mastinu, P; Pancin, J; Papadopoulos, C; Tagliente, G; Haight, R; Chepel, V; Kossionides, E; Badurek, G; Marganiec, J; Lukic, S; Pavlik, A; Goncalves, I; Duran, I; Alvarez, H; Abbondanno, U; Fujii, K; Milazzo, P M; Moreau, C

    2011-01-01

    The CERN Neutron Time-Of-Flight (n\\_TOF) facility is well suited to measure small neutron-induced fission cross sections, as those of subactinides. The cross section ratios of (nat)Pb and (209)Bi relative to (235)U and (238)U were measured using PPAC detectors. The fragment coincidence method allows to unambiguously identify the fission events. The present experiment provides the first results for neutron-induced fission up to 1 GeV for (nat)Pb and (209)Bi. A good agreement with previous experimental data below 200 MeV is shown. The comparison with proton-induced fission indicates that the limiting regime where neutron-induced and proton-induced fission reach equal cross section is close to 1 GeV.

  1. STX209 (Arbaclofen) for Autism Spectrum Disorders: An 8-Week Open-Label Study

    OpenAIRE

    Erickson, Craig A.; Veenstra-Vanderweele, Jeremy M.; Melmed, Raun D.; McCracken, James T.; Ginsberg, Lawrence D.; Sikich, Linmarie; Scahill, Lawrence; Cherubini, Maryann; Zarevics, Peter; Walton-Bowen, Karen; Carpenter, Randall L.; Wang, Paul P.; King, Bryan H.; Bear, Mark

    2013-01-01

    STX209 (arbaclofen), a selective GABA-B agonist, is hypothesized to modulate the balance of excitatory to inhibitory neurotransmission, and has shown preliminary evidence of benefit in fragile X syndrome. We evaluated its safety, tolerability, and efficacy in non-syndromic autism spectrum disorders, in an 8-week open-label trial enrolling 32 children and adolescents with either Autistic Disorder or Pervasive Developmental Disorder—Not Otherwise Specified, and a score ≥17 on the Aberrant Behav...

  2. Metabolic and Pharmacokinetic Differentiation of STX209 and Racemic Baclofen in Humans

    OpenAIRE

    Raymundo Sanchez-Ponce; Li-Quan Wang; Wei Lu; Jana von Hehn; Maryann Cherubini; Roger Rush

    2012-01-01

    STX209 is an exploratory drug comprising the single, active R-enantiomer of baclofen which is in later stage clinical trials for the treatment of fragile x syndrome (FXS) and autism spectrum disorders (ASD). New clinical data in this article on the metabolism and pharmacokinetics of the R- and S-enantiomers of baclofen presents scientific evidence for stereoselective metabolism of only S-baclofen to an abundant oxidative deamination metabolite that is sterically resolved as the S-enantiomeric...

  3. Interaction between FOXO1A-209 Genotype and Tea Drinking is Significantly Associated with Reduced Mortality at Advanced Ages

    DEFF Research Database (Denmark)

    Zeng, Yi; Chen, Huashuai; Ni, Ting;

    2016-01-01

    of the FOXO1A-209 genotype compared to non-carriers, and drinking tea is associated with a reversal of the negative effects of carrying FOXO1A-209 minor alleles, that is, from a substantially increased mortality risk to substantially reduced mortality risk at advanced ages. The impacts are considerably...... stronger among those who carry 2 copies of the FOXO1A minor allele than those who carry 1 copy. Based on previously reported experiments on human cell models concerning FOXO1A-by-tea-compounds interactions, we speculate that results in the present study indicate that tea drinking may inhibit FOXO1A-209...... gene expression and its biological functions, which reduces the negative impacts of FOXO1A-209 gene on longevity (as reported in the literature) and offers protection against mortality risk at oldest-old ages. Our empirical findings imply that the health outcomes of particular nutritional interventions...

  4. Molecular CO(1-0) gas in the z~2 radio galaxy MRC 0152-209

    CERN Document Server

    Emonts, B H C; Mao, M Y; Norris, R P; Miley, G; Ekers, R D; Villar-Martin, M; Rottgering, H J A; Sadler, E M; Rees, G; Morganti, R; Saikia, D J; Oosterloo, T A; Stevens, J B; Tadhunter, C N

    2011-01-01

    We report the detection of molecular CO(1-0) gas in the high-z radio galaxy MRC 0152-209 (z = 1.92) with the Australia Telescope Compact Array Broadband Backend (ATCA/CABB). This is the third known detection of CO(1-0) in a high-z radio galaxy to date. CO(1-0) is the most robust tracer of the overall molecular gas content (including the wide-spread, low-density and subthermally excited component), hence observations of CO(1-0) are crucial for studying galaxy evolution in the Early Universe. We derive L'(CO) = (6.6 +- 2.0) x 10^10 K km/s pc^2 for MRC 0152-209, which is comparable to that derived from CO(1-0) observations of several high-z submillimetre and starforming BzK galaxies. The CO(1-0) traces a total molecular hydrogen mass of M(H2) = 5 x 10^10 (alpha_x/0.8) Msun. MRC 0152-209 is an infra-red bright radio galaxy, in which a large reservoir of cold molecular gas has not (yet) been depleted by star formation or radio source feedback. Its compact radio source is reliably detected at 40 GHz and has a steep...

  5. Metabolic and Pharmacokinetic Differentiation of STX209 and Racemic Baclofen in Humans

    Directory of Open Access Journals (Sweden)

    Raymundo Sanchez-Ponce

    2012-09-01

    Full Text Available STX209 is an exploratory drug comprising the single, active R-enantiomer of baclofen which is in later stage clinical trials for the treatment of fragile x syndrome (FXS and autism spectrum disorders (ASD. New clinical data in this article on the metabolism and pharmacokinetics of the R- and S-enantiomers of baclofen presents scientific evidence for stereoselective metabolism of only S-baclofen to an abundant oxidative deamination metabolite that is sterically resolved as the S-enantiomeric configuration. This metabolite undergoes some further metabolism by glucuronide conjugation. Consequences of this metabolic difference are a lower Cmax and lower early plasma exposure of S-baclofen compared to R-baclofen and marginally lower urinary excretion of S-baclofen after racemic baclofen administration. These differences introduce compound-related exposure variances in humans in which subjects dosed with racemic baclofen are exposed to a prominent metabolite of baclofen whilst subjects dosed with STX209 are not. For potential clinical use, our findings suggest that STX209 has the advantage of being a biologically defined and active enantiomer.

  6. Far Infrared Mapping of Three Galactic Star Forming Regions: W3(OH), S209 & S187

    Indian Academy of Sciences (India)

    S. K. Ghosh; B. Mookerjea; T. N. Rengarajan; S. N. Tandon; R. P. Verma

    2001-06-01

    Three Galactic star forming regions associated with W3(OH), S209 and S187 have been simultaneously mapped in two trans-IRAS far infrared (FIR) bands centered at ∼ 140 and 200m using the TIFR 100 cm balloon borne FIR telescope. These maps showextended FIR emission with structures. The HIRES processed IRAS maps of these regions at 12, 25, 60 & 100 m have also been presented for comparison. Point-like sources have been extracted from the longest waveband TIFR maps and searched for associations in the other five bands. The diffuse emission from these regions have been quantified, which turns out to be a significant fraction of the total emission. The spatial distribution of cold dust (T < 30 K) for two of these sources (W3(OH) & S209), has been determined reliably from the maps in TIFR bands. The dust temperature and optical depth maps show complex morphology. In general the dust around S209 has been found to be warmer than that in W3(OH) region.

  7. A functional variant in the CD209 promoter is associated with DQ2-negative celiac disease in the Spanish population

    Institute of Scientific and Technical Information of China (English)

    C Nú(n)ez; E Urcelay; J Martín; B Rueda; A Martínez; C Maluenda; I Polanco; MA López-Nevot; E Ortega; E Sierra; E Gómez de la Concha

    2006-01-01

    AIM: To address the role of CD209 in celiac disease (CD)patients. Non-human leukocyte antigen (HLA) genetic factors in CD predisposition are poorly understood, and environmental factors like infectious pathogens may play a role. CD209 is a dendritic and macrophage surface molecule involved in pathogen recognition and immune activation. Recently, a functional variant in the promoter of the CD209 gene (-336A/G) has been shown to affect the transcriptional CD209 activity in vitro and it has been associated with a higher susceptibility to/or severity of infection.METHODS: The study population was composed of two case-control cohorts of 103 and 386 CD patients and 312 y 419 healthy controls as well as a panel of 257 celiac families. Genotyping for the -336A/G CD209promoter polymorphism was performed using a TaqMan 5' allelic discrimination assay. HLA-DQ was determined by hybridization with allele specific probes.RESULTS: Initially, the case-control and familial studies did not find any association of the -336 A/G CD209 genetic variant with CD susceptibility. However,the stratification by HLA-DQ2 did reveal a significant association of CD209 promoter polymorphism in the HLA-DQ2 (-) group (carrier Avs GG in DQ2 (-) vs DQ2 (+)patients (P = 0.026, OR = 3.71).CONCLUSION: The -336G CD209 allele seems to be involved in CD susceptibility in HLA-DQ2 (-) patients. Our results might suggest a possible role of pathogens in the onset of a minor group of CD patients.

  8. 西非209例中国人恶性疟临床分析%Analysis of 209 Chinese falciparum malaria patients in West Africa

    Institute of Scientific and Technical Information of China (English)

    杨景毅; 谢福生; Issa Malam Djibo

    2013-01-01

    Objective To observe clinical manifestation and therapy of the Chinese patients with Plasmodium falciparum malaria in West Africa. Methods A total of 209 Chinese cases with Plasmodium falciparum malaria diagnosed by laboratory examination were collected in West Africa, their clinical manifestations, results of laboratory examination and treatment were retrospectively analyzed. Results The clinical manifestation of 209 Chinese cases with Plasmodim falciparum malaria were not typical, complicated various, accompanied with headache, pharyngalgia, muscle ache, and lethargy symptoms etc., cough and expectoration of respiratory symptoms etc., abdominal pain, diarrhea, and vomiting of digestive tract symptoms etc., early, combined, grade, and system using arteannuines derivatives and type of quinine medicine, the clinical manifestations disappeared after antimalarial treatment, without cases of Plasmodium falciparum malaria, only 3 cases were found a few Plasmodium by laboratory review testing, who became carriers without symptoms. Conclusion The clinical manifestation of Plasmodium falciparum malaria were complicated, the malaria high area should be focused and bewared, the effects of early, combined, grade, and system antimalarial treatment were satisfied, which can effectively reduce and avoid falciparum malaria.%目的 探讨近年到西非的中国人感染恶性疟的临床特点及治疗方法.方法 收集西非国家209例实验室确诊的中国人恶性疟病例,对其临床表现、实验室检查结果、治疗方案及效果进行回顾性分析.结果 209例恶性疟临床表现不典型、复杂多样,可伴有头痛、咽痛、肌肉痛、怠倦等症候群、咳嗽、咳痰等呼吸道症状以及腹痛、腹泻、呕吐等消化道症状,采用青蒿素衍生物和奎宁类药物早期、联合、分级、系统抗疟治疗后症状均消失,无恶性疟重症病例发生,仅3例实验室复查仍有少量疟原虫,成为无症状带虫者.结论 恶

  9. MOR209/ES414, a Novel Bispecific Antibody Targeting PSMA for the Treatment of Metastatic Castration-Resistant Prostate Cancer.

    Science.gov (United States)

    Hernandez-Hoyos, Gabriela; Sewell, Toddy; Bader, Robert; Bannink, Jeannette; Chenault, Ruth A; Daugherty, Mollie; Dasovich, Maria; Fang, Hang; Gottschalk, Rebecca; Kumer, John; Miller, Robert E; Ravikumar, Padma; Wiens, Jennifer; Algate, Paul A; Bienvenue, David; McMahan, Catherine J; Natarajan, Sateesh K; Gross, Jane A; Blankenship, John W

    2016-09-01

    Treatment of metastatic, castration-resistant prostate cancer (mCRPC) remains a highly unmet medical need and current therapies ultimately result in disease progression. Immunotherapy is a rapidly growing approach for treatment of cancer but has shown limited success to date in the treatment of mCRPC. We have developed a novel humanized bispecific antibody, MOR209/ES414, built on the ADAPTIR (modular protein technology) platform, to redirect T-cell cytotoxicity toward prostate cancer cells by specifically targeting T cells through CD3ε to prostate cancer cells expressing PSMA (prostate-specific membrane antigen). In vitro cross-linking of T cells with PSMA-expressing tumor cells by MOR209/ES414 triggered potent target-dependent tumor lysis and induction of target-dependent T-cell activation and proliferation. This activity occurred at low picomolar concentrations of MOR209/ES414 and was effective at low T-effector to tumor target cell ratios. In addition, cytotoxic activity was equivalent over a wide range of PSMA expression on target cells, suggesting that as few as 3,700 PSMA receptors per cell are sufficient for tumor lysis. In addition to high sensitivity and in vitro activity, MOR209/ES414 induced limited production of cytokines compared with other bispecific antibody formats. Pharmacokinetic analysis of MOR209/ES414 demonstrated a serum elimination half-life in NOD/SCID γ (NSG) mice of 4 days. Administration of MOR209/ES414 in murine xenograft models of human prostate cancer significantly inhibited tumor growth, prolonged survival, and decreased serum prostate-specific antigen levels only in the presence of adoptively transferred human T cells. On the basis of these preclinical findings, MOR209/ES414 warrants further investigation as a potential therapeutic for the treatment of CRPC. Mol Cancer Ther; 15(9); 2155-65. ©2016 AACR. PMID:27406985

  10. Interethnic diversity of the CD209 (rs4804803 gene promoter polymorphism in African but not American sickle cell disease

    Directory of Open Access Journals (Sweden)

    Jenelle A. Noble

    2015-02-01

    Full Text Available Elucidating the genomic diversity of CD209 gene promoter polymorphism could assist in clarifying disease pathophysiology as well as contribution to co-morbidities. CD209 gene promoter polymorphism has been shown to be associated with susceptibility to infection. We hypothesize that CD209 mutant variants occur at a higher frequency among Africans and in sickle cell disease. We analyzed the frequency of the CD209 gene (rs4804803 in healthy control and sickle cell disease (SCD populations and determined association with disease. Genomic DNA was extracted from blood samples collected from 145 SCD and 231 control Africans (from Mali, 331 SCD and 379 control African Americans and 159 Caucasians. Comparative analysis among and between groups was carried out by polymerase chain reaction-restriction fragment length polymorphism (PCR-RFLP. Per ethnic diversification, we found significant disparity in genotypic (23.4% versus 16.9% versus 3.2% and allelic frequencies (48.7% versus 42.1% versus 19.8% of the homozygote mutant variant of the CD209 (snp 309A/G gene promoter between Africans, African Americans and Caucasians respectively. Comparative evaluation between disease and control groups reveal a significant difference in genotypic (10.4% versus 23.4%; p = 0.002 and allelic frequencies (39.7% versus 48.7%; p = 0.02 of the homozygote mutant variant in African SCD and healthy controls respectively, an observation that is completely absent among Americans. Comparing disease groups, we found no difference in the genotypic (p = 0.19 or allelic (p = 0.72 frequencies of CD209 homozygote mutant variant between Africans and Americans with sickle cell disease. The higher frequency of CD209 homozygote mutant variants in the African control group reveals a potential impairment of the capacity to mount an immune response to infectious diseases, and possibly delineate susceptibility to or severity of infectious co-morbidities within and between groups.

  11. Characterizing the optimal operation of photocatalytic degradation of BDE-209 by nano-sized TiO2

    Institute of Scientific and Technical Information of China (English)

    Ka Lai Chow; Yu Bon Man; Jin Shu Zheng; Yan Liang; Nora Fung Yee Tam; Ming Hung Wong

    2012-01-01

    Brominated flame retardants have been widely used in industry.There is a rapid growing public concern for their availabilities in the environment.Advanced oxidation process (AOP) is a promising and efficient technology which may be used to remove emerging chemicals such as brominated flame retardants.This study aims at investigating optimal operational conditions for the removal of BDE-209 using nano-scaled titanium(IV) oxide.The residual PBDE congeners after photocatalytical degradation of BDE-209 by TiO2 were analysed by gas chromatography-mass spectrometry (GC-MS).It was found that the degradability of BDE-209 by TiO2 was attributed to its photocatalytic activity but not the small size of the particles.The half-life of removing BDE-209 by TiO2 was 3.05 days under visible light.Tetra- and penta-BDEs were the major degraded products of BDE-209.Optimum conditions for photocatalytical degradation of BDE-209 was found to be at pH 12 (93% ± 1%),5,10,20 mg/L (93.0% ± 1.70%,91.6% ± 3.21%,91.9% ± 0.952%,respectively),respectively of humic acid and in the form of anatase/mtile YiO2 (82% ± 3%).Hence,the efficiency of removing BDE-209 can be maximized while being cost effective at the said operating conditions.

  12. Precision laser spectroscopy of the ground state hyperfine splitting of hydrogenlike ^209 Bi^82+

    OpenAIRE

    Klaft, Ingo; Borneis, Stefan; Engel, Thomas; Fricke, Burkhard; Grieser, Ralf; HUBER, GERHARD; Kühl, Thomas; Marx, Dieter; Neumann, Reinhard; Schröder, Sönke; Seelig, Peter; Völker, Lothar

    1994-01-01

    The first direct observation of a hyperfine splitting in the optical regime is reported. The wavelength of the M1 transition between the F = 4 and F = 5 hyperfine levels of the ground state of hydrogenlike ^209 Bi^82+ was measured to be \\lamda_0 = 243.87(4) nm by detection of laser induced fluorescence at the heavy-ion storage ring ESR at GSI. In addition, the lifetime of the laser excited F = 5 sublevel was determined to be \\tau_0 = 0.351(16) ms. The method can be applied to a number of othe...

  13. On the 209Po half-life error and its confirmation. A critique

    International Nuclear Information System (INIS)

    A recent report on 209Po claimed to have made a determination of the 125-a half-life from measurements made over 0.8 % of one half-life. A careful reanalysis of the original data with a more complete and rigorous consideration of the underlying uncertainties demonstrates that this claim cannot withstand critical scrutiny. More importantly, this critique examines the larger issue as to what constitutes a valid half-life determination, and highlights that a careful and realistic analysis beyond the mere fitting of decay data to an exponential function is required for the measurement and reporting of half-life values. (author)

  14. Measurement of $R_b$ in $e^+ e^-$ Collisions at 182 - 209 GeV

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Asai, S; Axen, D A; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brown, R M; Burckhart, H J; Campana, S; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Fanfani, A; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, R J; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanzaki, J; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krieger, P; Von Krogh, J; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Mashimo, T; Mättig, P; McKenna, J A; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Mohr, W; Montanari, A; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2005-01-01

    Measurements of Rb, the ratio of the bbbar cross-section to the qqbar cross- section in e+e- collisions, are presented. The data were collected by the OPAL experiment at LEP at centre-of-mass energies between 182 GeV and 209 GeV. Lepton, lifetime and event shape information is used to tag events containing b quarks with high efficiency. The data are compatible with the Standard Model expectation. The mean ratio of the eight measurements reported here to the Standard Model prediction is 1.055+-0.031+-0.037, where the first error is statistical and the second systematic.

  15. Cross-Section Measurements for Charm Production by 209-GeV Muons

    Energy Technology Data Exchange (ETDEWEB)

    Clark, A. R.; Johnson, K. J.; Kerth, L. T.; Loken, S. C.; Markiewicz, T. W.; Meyers, P. D.; Smith, W. H.; Strovink, M.; Wenzel, W. A.; Johnson, R. P.; Moore, C.; Mugge, M.; Shafer, R. E.; Gollin, G. D.; Shoemaker, F. C.; Surko, P.

    1980-09-01

    Interactions of 209-GeV muons in the Multimuon Spectrometer at Fermilab have yielded 20072 dimuon final states, with (81±10)% attributed to production of charmed states decaying to muons. The cross section for diffractive charm muoproduction is 6.9{sub -1.4}{sup +1.9} nb. Extrapolated to Q{sup 2} =0, the effective cross section for 178(100)-GeV photons is 750{sup +180}{sub -130} (560{sup +200}{sub -130}) nb, too small to explain the high-energy rise in the photon-nucleon total cross section.

  16. Constraints on the Radial Variation of Grain Growth in the AS 209 Circumstellar Disk

    CERN Document Server

    Pérez, Laura M; Chandler, Claire J; Isella, Andrea; Andrews, Sean M; Ricci, Luca; Calvet, Nuria; Corder, Stuartt A; Deller, Adam T; Dullemond, Cornelis P; Greaves, Jane S; Harris, Robert J; Henning, Thomas; Kwon, Woojin; Lazio, Joseph; Linz, Hendrik; Mundy, Lee G; Sargent, Anneila I; Storm, Shaye; Testi, Leonardo; Wilner, David J

    2012-01-01

    We present dust continuum observations of the protoplanetary disk surrounding the pre-main sequence star AS 209, spanning more than an order of magnitude in wavelength from 0.88 to 9.8 mm. The disk was observed with sub-arcsecond angular resolution (0.2"-0.5") to investigate radial variations in its dust properties. At longer wavelengths, the disk emission structure is notably more compact, providing model-independent evidence for changes in the grain properties across the disk. We find that physical models which reproduce the disk emission require a radial dependence of the dust opacity \\kappa_{\

  17. CDRI-08 Attenuates REST/NRSF-Mediated Expression of NMDAR1 Gene in PBDE-209-Exposed Mice Brain.

    Science.gov (United States)

    Verma, Priya; Gupta, Rajaneesh K; Gandhi, Behrose S; Singh, Poonam

    2015-01-01

    CDRI-08 is a standardized bacoside enriched ethanolic extract of Bacopa monnieri, a nootropic plant. We reported that CDRI-08 attenuated oxidative stress and memory impairment in mice, induced by a flame retardant, PBDE-209. In order to explore the mechanism, present study was designed to examine the role of CDRI-08 on the expression of NMDAR1 (NR1) and the binding of REST/NRSF to NR1 promoter against postnatal exposure of PBDE-209. Male mice pups were orally supplemented with CDRI-08 at the doses of 40, 80, or 120 mg/kg along with PBDE-209 (20 mg/kg) during PND 3-10 and frontal cortex and hippocampus were collected at PND 11 and 60 to study the expression and regulation of NR1 by RT-PCR and electrophoretic mobility shift assay, respectively. The findings showed upregulated expression of NR1 and decreased binding of REST/NRSF to NR1 promoter after postnatal exposure of PBDE-209. Interestingly, supplementation with CDRI-08 significantly restored the expression of NR1 and binding of REST/NRSF to NR1 promoter near to the control value at the dose of 120 mg/kg. In conclusion, the results suggest that CDRI-08 possibly acts on glutamatergic system through expression and regulation of NR1 and may restore memory, impaired by PBDE-209 as reported in our previous study.

  18. CDRI-08 Attenuates REST/NRSF-Mediated Expression of NMDAR1 Gene in PBDE-209-Exposed Mice Brain

    Directory of Open Access Journals (Sweden)

    Priya Verma

    2015-01-01

    Full Text Available CDRI-08 is a standardized bacoside enriched ethanolic extract of Bacopa monnieri, a nootropic plant. We reported that CDRI-08 attenuated oxidative stress and memory impairment in mice, induced by a flame retardant, PBDE-209. In order to explore the mechanism, present study was designed to examine the role of CDRI-08 on the expression of NMDAR1 (NR1 and the binding of REST/NRSF to NR1 promoter against postnatal exposure of PBDE-209. Male mice pups were orally supplemented with CDRI-08 at the doses of 40, 80, or 120 mg/kg along with PBDE-209 (20 mg/kg during PND 3–10 and frontal cortex and hippocampus were collected at PND 11 and 60 to study the expression and regulation of NR1 by RT-PCR and electrophoretic mobility shift assay, respectively. The findings showed upregulated expression of NR1 and decreased binding of REST/NRSF to NR1 promoter after postnatal exposure of PBDE-209. Interestingly, supplementation with CDRI-08 significantly restored the expression of NR1 and binding of REST/NRSF to NR1 promoter near to the control value at the dose of 120 mg/kg. In conclusion, the results suggest that CDRI-08 possibly acts on glutamatergic system through expression and regulation of NR1 and may restore memory, impaired by PBDE-209 as reported in our previous study.

  19. Effects of decabromodiphenyl ether (BDE-209 on inter-specific competition between two species of marine bloom-forming microalgae.

    Directory of Open Access Journals (Sweden)

    Xinxin Zhang

    Full Text Available Decabromodiphenyl ether (BDE-209, a new kind of persistent organic pollutants, was selected to investigate its influence on population growth and inter-specific competition between two species of marine bloom-forming microalgae, Heterosigma akashiwo and Karenia mikimotoi. (1BDE-209 showed acute toxic effects on both microalgae and H. akashiwo was more sensitive from view of 96 h-EC50 and the ultrastructure variation. (2The microalgal population growth patterns in mono-culture were density-dependent and the growth of both species in the normal co-culture was significantly depressed by competition (P<0.05 with different initial biomass ratios. BDE-209 exposure significantly changed the growth. (3 Lotka-Volterra competition model was used to simulate the interaction between the microalgae. BDE-209 exposure broke the competitive balance to make competition gradually shift in favor of H. akashiwo. Results suggested BDE-209 did have toxic effects on either microalgal growth or the inter-specific competition, which was quite different from previous reports. Further exploration of the mechanism is needed.

  20. CT in ureterolithiasis with a radiation dose equal to intravenous urography: results in 209 patients; CT der Ureterolithiasis mit der Strahlendosis einer Ausscheidungsurographie: Ergebnisse bei 209 Patienten

    Energy Technology Data Exchange (ETDEWEB)

    Knoepfle, E.; Bohndorf, K. [Klinikum Augsburg (Germany). Klinik fuer Diagnostische Radiologie und Neuroradiologie; Hamm, M.; Wartenberg, S. [Klinikum Augsburg (Germany). Klinik fuer Urologie

    2003-12-01

    Purpose: To evaluate a low-dose, nonenhanced helical CT protocol for the diagnosis of renal colic using an effective dose equivalent of radiation not higher than that of intravenous urography. Materials and Methods: A new low-dose helical-CT protocol (120 kV; 70 mA; rotation time 0.75 s; collimation 5 mm, pitch=2) was used to examine 209 consecutive patients with symptoms of renal colic. The initial CT reports were compared with retrograde ureterography, ureteral endoscopy, stone retrieval, surgical or clinical findings. The effective radiation dose was calculated by the method published by Nagel. The prevalence of ureterolithiasis was 70%. Results: Sensitivity and specificity of the low-dose-helical CT in detecting ureteral calculi were 97.7% and 96.8%, respectively. The positive predictive value was 99.3% and negative predictive value 92.4%. The mean effective radiation dose equivalent was 0.97 mSv in male and 1.35 mSv in female patients. Conclusions: the diagnostic value of the reported CT protocol does no differ from previously published protocols. However, the effective radiation dose equivalent is at least 50% lower than stated in the published protocols. We recommend the low-dose helical CT protocol as the method of choice. (orig.) [German] Fragestellung: Pruefung der diagnostischen Aussagekraft eines nativen Spiral-CT-Protokolls mit einer niedrigen, einer Ausscheidungsurographie aequivalenten Strahlendosis bei der Abklaerung einer Harnleiterkolik. Methode: 209 konsekutive Patienten mit der klinischen Verdachtsdiagnose einer Harnleiterkolik wurden mit einem neuen CT-Protokoll untersucht (120 kV; 70 mA; Rotationszeit 0,75 s; Kollimation 5 mm; Pitch=2). Die prospektiv erhobenen CT-Befunde wurden mittels retrograder Ureterdarstellung, Ureterendoskopie, Steinasservierung, operativ oder im klinischen Verlauf validiert. Die effektive Dosis der CT-Untersuchung wurde nach Nagel berechnet. Die Praevalenz der Ureterolithiasis betrug 70%. Ergebnisse: Die Niedrig

  1. The Extremely Low Activity Comet 209P/LINEAR During Its Extraordinary Close Approach in 2014

    CERN Document Server

    Schleicher, David G

    2016-01-01

    We present results from our observing campaign of Comet 209P/LINEAR during its exceptionally close approach to Earth during May of 2014, the third smallest perigee of any comet in two centuries. These circumstances permitted us to pursue several studies of this intrinsically faint object, including measurements of gas and dust production rates, searching for coma morphology, and direct detection of the nucleus to measure its properties. Indeed, we successfully measured the lowest water production rates of an intact comet in over 35 years and a corresponding smallest active area, ~0.007 km^2. When combined with the nucleus size found from radar (Howell et al. 2014), this also yields the smallest active fraction for any comet, ~0.024%. In all, this strongly suggests that 209P/LINEAR is on its way to becoming an inert object. The nucleus was detected but could not easily be disentangled from the inner coma due to seeing variations and changing spatial scales. Even so, we were able to measure a double-peaked ligh...

  2. Will Comet 209P/LINEAR Generate the Next Meteor Storm?

    CERN Document Server

    Ye, Quanzhi

    2013-01-01

    Previous studies have suggested that Comet 209P/LINEAR may produce strong me- teor activity on Earth on 2014 May 24; however, exact timing and activity level is difficult to estimate due to the limited physical observations of the comet. Here we reanalyze the optical observations of 209P/LINEAR obtained during its 2009 appari- tion. We find that the comet is relatively depleted in dust production, with Af {\\rho} at 1 cm level within eight months around its perihelion. This feature suggested that this comet may be currently transitioning from typical comet to a dormant comet. Syn- dyne simulation shows that the optical cometary tail is dominated by larger particles with {\\beta} ~ 0.003. Numerical simulations of the cometary dust trails confirm the arrival of particles on 2014 May 24 from some of the 1798-1979 trails. The nominal radiant is at RA 122 +/- 1 deg, Dec 79 +/- 1 deg (J2000) in the constellation of Camelopardalis. Given that the comet is found to be depleted in dust production, we concluded that a me...

  3. Coulomb breakup effects on the elastic cross section of $^6$He+$^{209}$Bi scattering near Coulomb barrier energies

    CERN Document Server

    Matsumoto, T; Iseri, Y; Kamimura, M; Ogata, K; Yahiro, M

    2006-01-01

    We accurately analyze the $^6$He+$^{209}$Bi scattering at 19 and 22.5 MeV near the Coulomb barrier energy, using the continuum-discretized coupled-channels method (CDCC) based on the $n$+$n$+$^4$He+$^{209}$Bi four-body model. The three-body breakup continuum of $^6$He is discretized by diagonalizing the internal Hamiltonian of $^6$He in a space spanned by the Gaussian basis functions. The calculated elastic and total reaction cross sections are in good agreement with the experimental data, while the CDCC calculation based on the di-neutron model of $^6$He, i.e., the $^2n$+$^{4}$He+$^{209}$Bi three-body model, does not reproduce the data.

  4. 45 CFR 400.209 - Claims involving family units which include refugees who have been in the United States more than...

    Science.gov (United States)

    2010-10-01

    ... refugees who have been in the United States more than 36 months. 400.209 Section 400.209 Public Welfare Regulations Relating to Public Welfare OFFICE OF REFUGEE RESETTLEMENT, ADMINISTRATION FOR CHILDREN AND FAMILIES, DEPARTMENT OF HEALTH AND HUMAN SERVICES REFUGEE RESETTLEMENT PROGRAM Federal Funding...

  5. 十溴联苯醚(BDE-209)对成年大鼠甲状腺激素的影响%Disturbance of Decabrominated Diphenyl Ether(BDE-209)to Thyroid Hormones of Adult Rats in Vivo

    Institute of Scientific and Technical Information of China (English)

    李欣年; 黄敏; 虞太六

    2009-01-01

    多溴联苯醚(PBDEs)是现代工业中广泛应用的溴系阻燃剂,PBDEs具有持久性有机卤素污染物(Organohalogen Contaminants,OHCs)和内分泌干扰物(Endocrine Disrupters,EDs)的化学物理特性.PBDEs的生物毒性也是国际上环境生态科学的关注热点.论文建立了十溴联苯醚(BDE-209)暴露剂茸的成年大鼠模型,测定了不同暴露剂量的实验动物血清甲状腺激素(Thyroid hormones,THs)水平,初步研究了PBDEs污染物对生物体甲状腺激素的影响.BDE-209的量-效关系研究结果显示,TT4、FT4和TT3浓度均随着暴露剂量的提高而下降,这可能是BDE-209对甲状腺合成分泌T4、T3起到了抑制作用.不同BDE-209暴露剂量下,TT4~FT4以及TT4~FT4的正相关系数大于FT3~TT3,以及FT3~FT4,这意味着BDE-209暴露对于T4从甲状腺激素转运结合蛋白(Transthyretin,TTR)的分离与脱碘过程影响不明显,而影响了结合态T3从TTR的分离过程以及FT4的脱碘过程,从而对甲状腺激素的平衡具有干扰效应.采用基准点分析法,研究了BDE-209对于甲状腺干扰相对效应的时间-效应关系,实验表明由于甲状腺的应激作用,对于毒物具有自我防御功能,BDE-209对甲状腺的干扰效应在5~8d后才有所显现,持续时间至少为14d.

  6. Acute and Chronic Toxic Effect of Decabromodiphenyl Ether (BDE-209) on Soil-Dwelling Springtails%十溴联苯醚(BDE-209)对土壤跳虫的急、慢性毒性效应

    Institute of Scientific and Technical Information of China (English)

    张轩; 张偲; 王光鹏; 乔敏; 朱永官

    2012-01-01

    为揭示溴代阻燃剂对土壤生态系统的潜在危害,采用回避实验和繁殖实验评价了十溴联苯醚(BDE-209)对2种土壤跳虫Folsomia candida和Folsomia fimetaria的急/慢性毒性.48 h的急性回避实验中,BDE-209对F.candida和F.fimetaria产生毒性效应的EC50值分别为1.27和0.79 mg· kg,LOEC值均小于0.5 mg· kg.慢性繁殖实验中,BDE-209对F.candida和F.fimetaria繁殖毒性的EC50值分别为0.81和0.56 mg ·kg-1,LOEC值分别为<0.25和<0.5 mg· kg-1.研究表明,土壤BDE-209污染对跳虫的繁殖和环境行为有显著影响,且在较低暴露浓度下(0.25 mg· kg)即对跳虫繁殖产生抑制效应;有性生殖的F.fime-taria比孤雌生殖的F.candida对BDE-209污染的毒性响应更为敏感.

  7. Measurements of high-energy neutron-induced fission ofnatPb and 209Bi

    Directory of Open Access Journals (Sweden)

    Couture A.

    2010-10-01

    Full Text Available The CERN Neutron Time-Of-Flight (n_TOF facility is well suited to measure low cross sections as those of neutron-induced fission in subactinides. The cross section ratios of natPb and 209Bi relative to 235U and 238U were measured using PPAC detectors and a fragment coincidence method that allows us to identify the fission events. The present experiment provides first results for neutron-induced fission up to 1 GeV. Good agreement is found with previous experimental data below 200 MeV. The comparison with proton-induced fission indicates that the limiting regime where neutron-induced and proton-induced fission reach equal cross sections is close to 1 GeV.

  8. Prediction of Aqueous Solubility for 209 Polychlorinated Diphenyl Ethers from Molecular Structural Parameters by DFT Method

    Institute of Scientific and Technical Information of China (English)

    XIE Ya-Jie; LIU Hong-Xia; WANG Zun-Yao; ZHU Li-Dan

    2008-01-01

    Optimized calculations of 209 polychlorinated diphenyl ethers (PCDEs) and diphenyl ethers were carried out at the B3LYP/6-31G* level with the Gaussian 98 program. Based on the theoretical linear solvation energy relationship (TLSER) model, the obtained structural parameters were taken as theoretical descriptors to establish the novel QSPR model for predicting aqueous solubility (-lgSw) of PCDEs. The model obtained in this work contains two variables: mean molecular polarizability (α) and the most positive partial charge on a hydrogen atom (qH+), of which R2 = 0.9606 and SD = 0.32. And the results of cross-validation test also show that the model exhibits optimum stability and better predictive power. Moreover, the predictive power of the new model is better than that of MCIs method.

  9. ZZ production in $e^{+}e^{-}$ interactions at $\\sqrt{s}$ = 183 - 209 GeV

    CERN Document Server

    Abdallah, J; Adam, W; Adzic, P; Albrecht, T; Alderweireld, T; Alemany-Fernandez, R; Allmendinger, T; Allport, P P; Amaldi, Ugo; Amapane, N; Amato, S; Anashkin, E; Andreazza, A; Andringa, S; Anjos, N; Antilogus, P; Apel, W D; Arnoud, Y; Ask, S; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Ballestrero, A; Bambade, P; Barbier, R; Bardin, Dimitri Yuri; Barker, G; Baroncelli, A; Battaglia, Marco; Baubillier, M; Becks, K H; Begalli, M; Behrmann, A; Ben-Haim, E; Benekos, N C; Benvenuti, Alberto C; Bérat, C; Berggren, M; Berntzon, L; Bertrand, D; Besançon, M; Besson, N; Bloch, D; Blom, M; Bluj, M; Bonesini, M; Boonekamp, M; Booth, P S L; Borisov, G; Botner, O; Bouquet, B; Bowcock, T J V; Boyko, I; Bracko, M; Brenner, R; Brodet, E; Brückman, P; Brunet, J M; Bugge, L; Buschmann, P; Calvi, M; Camporesi, T; Canale, V; Carena, F; Castro, N; Cavallo, F R; Chapkin, M M; Charpentier, P; Checchia, P; Chierici, R; Shlyapnikov, P; Chudoba, J; Chung, S U; Cieslik, K; Collins, P; Contri, R; Cosme, G; Cossutti, F; Costa, M J; Crawley, B; Crennell, D J; Cuevas-Maestro, J; D'Hondt, J; Dalmau, J; Da Silva, T; Da Silva, W; Della Ricca, G; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Maria, N; De Min, A; De Paula, L S; Di Ciaccio, Lucia; Di Simone, A; Doroba, K; Drees, J; Dris, M; Eigen, G; Ekelöf, T J C; Ellert, M; Elsing, M; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Feindt, M; Fernández, J; Ferrer, A; Ferro, F; Flagmeyer, U; Föth, H; Fokitis, E; Fulda-Quenzer, F; Fuster, J A; Gandelman, M; García, C; Gavillet, P; Gazis, E N; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; Graziani, E; Grosdidier, G; Grzelak, K; Guy, J; Haag, C; Hallgren, A; Hamacher, K; Hamilton, K; Hansen, J; Haug, S; Hauler, F; Hedberg, V; Hennecke, M; Herr, H; Hoffman, J; Holmgren, S O; Holt, P J; Houlden, M A; Hultqvist, K; Jackson, J N; Jarlskog, G; Jarry, P; Jeans, D; Johansson, E K; Johansson, P D; Jonsson, P; Joram, C; Jungermann, L; Kapusta, F; Katsanevas, S; Katsoufis, E C; Kernel, G; Kersevan, Borut P; Kiiskinen, A P; King, B T; Kjaer, N J; Kluit, P; Kokkinias, P; Kourkoumelis, C; Kuznetsov, O; Krumshtein, Z; Kucharczyk, M; Lamsa, J; Leder, G; Ledroit, F; Leinonen, L; Leitner, R; Lemonne, J; Lepeltier, V; Lesiak, T; Liebig, W; Liko, D; Lipniacka, A; Lopes, J H; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Malek, A; Maltezos, S; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Masik, J; Mastroyiannopoulos, N; Matorras, F; Matteuzzi, C; Mazzucato, F; Mazzucato, M; McNulty, R; Meroni, C; Meyer, W T; Migliore, E; Mitaroff, W A; Mjörnmark, U; Moa, T; Moch, M; Mönig, K; Monge, R; Montenegro, J; Moraes, D; Moreno, S; Morettini, P; Müller, U; Münich, K; Mulders, M; Mundim, L M; Murray, W; Muryn, B; Myatt, Gerald; Myklebust, T; Nassiakou, M; Navarria, Francesco Luigi; Nawrocki, K; Nicolaidou, R; Nikolenko, M; Oblakowska-Mucha, A; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, Risto; Österberg, K; Ouraou, A; Oyanguren, A; Paganoni, M; Paiano, S; Palacios, J P; Palka, H; Papadopoulou, T D; Pape, L; Parkes, C; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Peralta, L; Perepelitsa, V F; Perrotta, A; Petrolini, A; Piedra, J; Pieri, L; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Poireau, V; Pol, M E; Polok, G; Poropat, P; Pozdnyakov, V; Pukhaeva, N; Pullia, Antonio; Rames, J; Ramler, L; Read, A; Rebecchi, P; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Richard, F; Rídky, J; Rivero, M; Rodríguez, D; Romero, A; Ronchese, P; Rosenberg, E I; Roudeau, Patrick; Rovelli, T; Ruhlmann-Kleider, V; Ryabtchikov, D; Sadovskii, A; Salmi, L; Salt, J; Savoy-Navarro, A; Schwickerath, U; Segar, A; Sekulin, R L; Siebel, M; Sissakian, A N; Smadja, G; Smirnova, O G; Sokolov, A; Sopczak, A; Sosnowski, R; Spassoff, Tz; Stanitzki, M; Stocchi, A; Strauss, J; Stugu, B; Szczekowski, M; Szeptycka, M; Szumlak, T; Tabarelli de Fatis, T; Taffard, A C; Tegenfeldt, F; Timmermans, J; Tkatchev, L G; Tobin, M; Todorovova, S; Tomé, B; Tonazzo, A; Tortosa, P; Travnicek, P; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M L; Tyapkin, I A; Tyapkin, P; Tzamarias, S; Uvarov, V; Valenti, G; van Dam, P; Van Eldik, J; Van Lysebetten, A; Van Remortel, N; Van Vulpen, I B; Vegni, G; Veloso, F; Venus, W A; Verbeure, F; Verdier, P; Verzi, V; Vilanova, D; Vitale, L; Vrba, V; Wahlen, H; Washbrook, A J; Weiser, C; Wicke, D; Wickens, J H; Wilkinson, G; Winter, M; Witek, M; Yushchenko, O P; Zalewska-Bak, A; Zalewski, Piotr; Zavrtanik, D; Zhuravlov, V; Zimin, N I; Zinchenko, A I; Zupan, M

    2003-01-01

    Measurements of on-shell ZZ production are described, using data from the DELPHI experiment at LEP in e+e- collisions at centre-of-mass energies between 183 and 209 GeV, corresponding to an integrated luminosity of about 665 pb^{-1}. Results obtained in each of the final states q anti-q q anti-q, nu anti-nu q anti-q, mu+ mu- q anti-q, e+ e- q anti-q, tau+ tau- q anti-q, l+ l- l+ l-, and nu anti-nu l+ l- (with l=e,mu) are presented. The measured production cross-sections are consistent with the Standard Model expectations. These results update and supersede those already published at 183 and 189 GeV.

  10. An Analysis of Therapeutic Effect of Drug Acupoint Application in 209 Cases of Allergic Asthma

    Institute of Scientific and Technical Information of China (English)

    赖新生; 李月梅; 范兆金; 张家维; 刘炳权

    2001-01-01

    Both therapies of traditional crude herb moxibustion and drug acupoint application were used in 209 cases of allergic asthma to compare their long-term and short-term therapeutic effects and to analyze the relationship between clinic therapeutic effects of both therapies and differential types of the disease. The results showed that the short-term total effective rate in the group of drug acupoint application was higher than that in the group of traditional crude herb moxibustion, the therapeutic effects of drug acupoint application being closely related to differential types. Analysis also shows the best short-term therapeutic effect was in the type of heat in the lung while the poorest effect in the type of deficiency of the kidney-yang.

  11. 44 CFR 206.209 - Arbitration for Public Assistance determinations related to Hurricanes Katrina and Rita (Major...

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Arbitration for Public... ASSISTANCE Public Assistance Project Administration § 206.209 Arbitration for Public Assistance... 2009, Public Law 111-5, this section establishes procedures for arbitration to resolve disputed...

  12. 33 CFR 209.325 - Navigation lights, aids to navigation, navigation charts, and related data policy, practices and...

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Navigation lights, aids to... ADMINISTRATIVE PROCEDURE § 209.325 Navigation lights, aids to navigation, navigation charts, and related data... procedure to be used by all Corps of Engineers installations and activities in connection with aids...

  13. Estimating and projecting the effect of cold waves on mortality in 209 US cities.

    Science.gov (United States)

    Wang, Yan; Shi, Liuhua; Zanobetti, Antonella; Schwartz, Joel D

    2016-09-01

    The frequency, duration, and intensity of cold waves are expected to decrease in the near future under the changing climate. However, there is a lack of understanding on future mortality related to cold waves. The present study conducted a large-scale national projection to estimate future mortality attributable to cold waves during 1960-2050 in 209 US cities. Cold waves were defined as two, three, or at least four consecutive days with daily temperature lower than the 5th percentile of temperatures in each city. The lingering period of a cold wave was defined as the non-cold wave days within seven days following that cold wave period. First, with 168million residents in 209 US cities during 1962-2006, we fitted over-dispersed Poisson regressions to estimate the immediate and lingering effects of cold waves on mortality and tested if the associations were modified by the duration of cold waves, the intensity of cold waves, and mean winter temperature (MWT). Then we projected future mortality related to cold waves using 20 downscaled climate models. Here we show that the cold waves (both immediate and lingering) were associated with an increased but small risk of mortality. The associations varied substantially across climate regions. The risk increased with the duration and intensity of cold waves but decreased with MWT. The projected mortality related to cold waves would decrease from 1960 to 2050. Such a decrease, however, is small and may not be able to offset the potential increase in heat-related deaths if the adaptation to heat is not adequate.

  14. Effect of BDE-209 on Structures and Oxidative Stress in Testicles of Rats%BDE-209对雄性大鼠睾丸组织结构和氧化应激的影响

    Institute of Scientific and Technical Information of China (English)

    李祥; 汤艳; 熊伟; 于雪岚; 刘扬

    2011-01-01

    目的 观察十溴联苯醚(brominated diphenyl ethers-209,BDE-209)对雄性大鼠睾丸组织形态结构和氧化应激的影响.方法 将96只健康成年SD雄性大鼠随机分为4组,分别为溶剂对照(花生油)组和低剂量(250 mg/kg)、中剂量(500 mg/kg)、高剂量(1 000 mg/kg)BDE-209染毒组,每组24只.采用灌胃方式进行染毒,BDE-209浓度为100 mg/ml,染毒容量分别为2.5、5、10 ml/kg,对照组按10 ml/kg灌胃给予纯花生油,每天1次,连续染毒30 d.测定睾丸组织的总抗氧化能力(T-AOC)、谷胱甘肽过氧化物酶(GST)、超氧化物歧化酶(SOD)、丙二醛(MDA)的水平,并观察大鼠睾丸组织的形态结构.结果 与溶剂对照组比较,各剂量BDE-209染毒组大鼠睾丸组织的重量、脏器系数、T-AOC、GST、SOD的活力均下降,MDA含量升高,差异有统计学意义(P<0.05);且随着BDE-209染毒剂量的升高,大鼠睾丸组织T-AOC、GST、SOD的活力均呈下降趋势,MDA含量呈上升趋势.光镜下观察发现,随着BDE-209染毒剂量的增加,大鼠睾丸组织曲精管内细胞层次减少,细胞质减少,精子数目减少.电镜下观察发现,染毒组大鼠生精细胞和精子细胞均有不同程度的损害.结论 BDE-209染毒对雄性成年大鼠睾丸组织的形态结构和氧化应激具有一定的损害.%bjective To establish the effects of brominated diphenyl ethers-209 (BDE-209) exposure on structures and oxidative stress in testicles of rats. Methods A total of 96 healthy male SD rats, 250-300 g, were randomly divided into four groups, including one solvent control group and three BDE-209-treated groups. The exposure groups were treated with BDE-209, at the doses of 250,500 and 1 000 mg/kg respectively, through gavage once a day, for 30 consecutive days. The rats in solvent control group received 1 000 mg/kg of peanut oil. The morphological changes of testicles were observed. Total oxidizing ability(T-AOC), glutathion peroxidase GST, superoxide dismutase

  15. 209周期宫腔内人工授精的临床分析%Clinical analysis on intrauterine insemination (IUI) in 209 cycles

    Institute of Scientific and Technical Information of China (English)

    凌秀凤; 顾林; 陈静琴; 王培; 张军强; 翁莉; 赵静

    2006-01-01

    目的:比较不同治疗方案对宫腔内人工授精(IUI)结局的影响,探讨较好的治疗方案以提高IUI的成功率.方法:回顾性分析了162例病人209个IUI治疗周期的治疗方案,根据病人用药情况分为3组:自然周期/IUI组、尿促卵泡素(hMG/IUI)组、克罗米芬(CC)+补佳乐/IUI组,比较各组病人在注射hCG日的子宫内膜厚度、卵泡发育情况、及妊娠结局等.结果:在162例病人中,有20例获得临床妊娠,临床妊娠率为12.34%,周期妊娠率为9.56%;3组病人的年龄、不孕年限,体重指数(BMI)及基础FSH、血清黄体生成素(LH)值、E2无差异;促排卵后,CC+补佳乐/IUI、hMG/IUI组病人的卵泡数高于自然周期组,子宫内膜厚度在自然周期组和hMG/IUI组明显高于CC+补佳乐/IUI组,有极显著性差异,P<0.01;妊娠结局3组分别为9、5、6.结论:IUI是治疗非输卵管因素不孕的一种有效方法,并且自然周期情况下,病人体内激素环境更接近于生理状况,能获得较好的妊娠结局.

  16. Bioconcentration and metabolism of BDE-209 in the presence of titanium dioxide nanoparticles and impact on the thyroid endocrine system and neuronal development in zebrafish larvae.

    Science.gov (United States)

    Wang, Qiangwei; Chen, Qi; Zhou, Peng; Li, Wenwen; Wang, Junxia; Huang, Changjiang; Wang, Xianfeng; Lin, Kuangfei; Zhou, Bingsheng

    2014-08-01

    Interactions between organic toxicants and nanoparticles (NPs) in the aquatic environment may modify toxicant bioavailability and consequently the toxicant's environmental fate and toxicity. Therefore, we investigated the influence of titanium dioxide NPs (nano-TiO2) on deca-BDE (BDE-209; a polybrominated diphenyl ether congener) bioconcentration, metabolism and its effects on the thyroid endocrine system in zebrafish (Danio rerio) larvae. Zebrafish embryos were exposed to various concentrations of BDE-209 alone or in combination with nano-TiO2 (0.1 mg/L) until 7-day post-fertilization. Nano-TiO2 can adsorb BDE-209 and nano-TiO2 is taken up into developing zebrafish larvae. Chemical measurements showed that BDE-209 was bioconcentrated and metabolized in zebrafish larvae, and BDE-209 uptake was enhanced by nano-TiO2. Furthermore, increased BDE-209 metabolites were detected in larvae co-exposed with nano-TiO2. BDE-209 exposure significantly increased whole-body thyroid hormone contents (T3 and T4); T4 content significantly increased in the larvae co-exposed with nano-TiO2. Nano-TiO2 exposure alone did not induce generation of reactive oxygen species, lipid peroxidative oxidation, gene transcription or thyroid hormone levels. Upregulation of several gene transcriptions (tshβ, tg, dio2) in the hypothalamic-pituitary-thyroid axis was also observed. Furthermore, co-exposure of nano-TiO2 and BDE-209 caused a decrease in locomotion activity and downregulation of specific genes and proteins involved in the central nervous system of developing zebrafish larvae (e.g. myelin basic protein and α1-tubulin). These results indicate nano-TiO2 enhances BDE-209 bioavailability and metabolism, leading to thyroid endocrine disruption and developmental neurotoxicity in zebrafish.

  17. Transference of particles in the fusion process of {sup 6}He + {sup 209}Bi; Transferencia de particulas en el proceso de fusion de {sup 6}He + {sup 209}Bi

    Energy Technology Data Exchange (ETDEWEB)

    Lizcano, D.; Aguilera, E.F.; Martinez Q, E. [Instituto Nacional de Investigaciones Nucleares, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    2000-07-01

    In a recent work were reported measurements done to energy which was to the Coulomb barrier for the {sup 6} He + {sup 209} Bi system. The fusion excitation function measured for this system shows a strong enhancement with respect to the predictions of the penetration model of unidimensional barrier at minor energies to the Coulombian barrier. In basis with the results obtained for different degrees of freedom it was determined with the CCDEF code, that the transfer of 2 neutrons of {sup 6} He to binding states to {sup 209} Bi, producing {sup 211} Bi, is the mechanism looked as the best candidate for explain the great enhancement in the fusion excitation function of this system at energies under Coulomb barrier. It is corroborated what was affirmed by others authors about the strength value at 1.5 MeV as a typical value for the transference of two particles between the projectile and the target. (Author)

  18. Simultaneous description of CF, ICF and TF data of 6,7Li + 209Bi reaction using new ICF mode

    International Nuclear Information System (INIS)

    The systematic behavior of the fusion suppression factors and ICF probability as a function of target mass is not well understood, despite the CF experimental data being available for a number of projectile-target systems. In our recent paper, a new method was proposed to calculate the ICF probability which is based on absorption cross sections obtained from the CDCC calculations. In continuation of this work, we have also carried out similar calculations for 6,7Li + 209Bi where the experimental data of CF and ICF is available. In the recent paper by Marta et al., the semi-classical model calculations were attempted to understand CF and ICF data for 6,7Li + 209Bi, which was not explaining the data quite well. Here, we have demonstrated the use of quantum mechanical treatment for simultaneous explanation of CF, ICF and TF over a large energy range

  19. Global Properties of the Rich Cluster ABCG 209 at z~0.2. Spectroscopic and Photometric Catalogue

    CERN Document Server

    Mercurio, A; Haines, C P; Merluzzi, P; Busarello, G; Capaccioli, M

    2008-01-01

    This paper is aimed at giving an overview of the global properties of the rich cluster of galaxies ABCG 209. This is achieved by complementing the already available data with new medium resolution spectroscopy and NIR photometry which allow us to i) analyse in detail the cluster dynamics, distinguishing among galaxies belonging to different substructures and deriving their individual velocity distributions, using a total sample of 148 galaxies in the cluster region, of which 134 belonging to the cluster; ii) derive the cluster NIR luminosity function; iii) study the Kormendy relation and the photometric plane of cluster early-type galaxies (ETGs). Finally we provide an extensive photometric (optical and NIR) and spectroscopic dataset for such a complex system to be used in further analyses investigating the nature, formation and evolution of rich clusters of galaxies. The observational scenario confirms that ABCG 209 is presently undergoing strong dynamical evolution with the merging of two or more subclumps....

  20. Evidence for a CO desorption front in the outer AS 209 disk

    CERN Document Server

    Huang, Jane; Andrews, Sean M

    2016-01-01

    Millimeter observations of CO isotopologues are often used to make inferences about protoplanetary disk gas density and temperature structures. The accuracy of these estimates depends on our understanding of CO freezeout and desorption from dust grains. Most models of these processes indicate that CO column density decreases monotonically with distance from the central star due to a decrease in gas density and freezeout beyond the CO snowline. We present ALMA Cycle 2 observations of $^{12}$CO, $^{13}$CO, and C$^{18}$O $J=2-1$ emission that instead suggest CO enhancement in the outer disk of T Tauri star AS 209. Most notably, the C$^{18}$O emission consists of a central peak and a ring at a radius of $\\sim1''$ (120 AU), well outside the expected CO snowline. We propose that the ring arises from the onset of CO desorption near the edge of the millimeter dust disk. CO desorption exterior to a CO snowline may occur via non-thermal processes involving cosmic rays or high-energy photons, or via a radial thermal inv...

  1. Life time of the HFS transition in Li-like {sup 209}Bi{sup 80+}

    Energy Technology Data Exchange (ETDEWEB)

    Geppert, C.; Noertershaeuser, W. [Institut fuer Kernchemie, Uni Mainz (Germany); GSI, Darmstadt (Germany); Hannen, V.; Joehren, R.; Ortjohann, H.W.; Vollbrecht, J.; Weinheimer, C. [Institut fuer Kernphysik, Uni Muenster (Germany); Kuehl, T. [Institut fuer Kernchemie, Uni Mainz (Germany); GSI, Darmstadt (Germany); Helmholtz Institut Jena (Germany); S' anchez, R.; Winters, D. [GSI, Darmstadt (Germany); Stoehlker, T. [Institut fuer Kernchemie, Uni Mainz (Germany); GSI, Darmstadt (Germany); Helmholtz Institut Jena (Germany); Uni Jena (Germany)

    2014-07-01

    Measuring the hyperfine splitting of heavy, highly charged ions enables tests of QED in strong fields. HFS calculations have a relative uncertainty of more than 10{sup -3} due to the distribution of the magnetic moment (Bohr-Weisskopf-Effekt). With an appropriate comparison of H- and Li-like ions this nuclear structure contribution can be suppressed. Bismuth is a suitable element for these studies, as the HFS splitting for both configurations are in a wavelength range suitable for laser spectroscopy. For this purpose the two ion species were stored in the Experimental Storage Ring at GSI at a velocity of β = 0.71. To efficiently collect the forward emitted photons a specially developed movable detector system was used. Thereby the HFS of Li-like {sup 209}Bi{sup 80+} was successfully measured for the first time. Besides the determination of the transition energy it was possible to extract the lifetime of the transition out of the collected data. The corresponding analysis and the results are presented on this poster.

  2. Comet 209P/LINEAR and the associated Camelopardalids meteor shower

    Science.gov (United States)

    Ye, Q.; Hui, M.; Wiegert, P.; Campbell-Brown, M.; Brown, P.; Weryk, R.

    2014-07-01

    Previous studies have suggested that comet 209P/LINEAR may produce strong meteor activity on the Earth on 2014 May 24. Here we present our observations and simulations prior to the event. We reanalyze the optical observations of P/LINEAR obtained during its 2009 apparition to model the corresponding meteor stream. We find that the comet is relatively depleted in dust production, with Afρ at 1-cm level within eight months around its perihelion. A syndyne simulation shows that the optical cometary tail is dominated by larger particles with β˜0.003. Numerical simulation of the cometary dust trails confirms the arrival of particles on 2014 May 24 from some of the 1798--1979 trails, with nominal radiant in the constellation of Camelopardalis. Given that the comet is found to be depleted in dust production, we concluded that a meteor storm may be unlikely. However, our simulation also shows that the size distribution of the arrived particles is skewed strongly towards larger particles, which, coupling with the result of the syndyne simulation, suggested that the event (if detectable) may be dominated by bright meteors. Preliminary results from the observations of P/LINEAR during its 2014 apparition as well as the Camelopardalids meteor shower will also be presented.

  3. Underground Research Laboratory room 209 instrument array. Vol. 1,2

    International Nuclear Information System (INIS)

    An in situ excavation response test was conducted at the 240 Level of the Underground Research Laboratory (URL). The test was carried out in conjunction with the drill-and-blast excavation of a near-circular tunnel (Room 209), about 3.5 m in diameter. The tunnel was excavated through a tunnel axis. Three modelling groups made predictions of the response of the rock mass and hydraulic behaviour of the water-bearing fracture to excavation. The tunnel was excavated in two stages, a pilot tunnel followed by a slash, providing two complete sets of response measurements. Careful excavation was carried out to ensure the excavation shape after each blast round agreed closely with the planned shape incorporated in the numerical models. Instrumentation installed before the tunnel was extended monitored the complete strain tensor at eight locations around the tunnel, radial displacements and piezometric pressures at nine locations in the fracture. As well, tunnel convergence, water flows from the fracture, and hydraulic conductivity of the fracture at nine locations, were measured after each excavation step. The final tunnel profiles were accurately surveyed, and the geology was mapped in detail. The results are presented in this report for comparison with the modellers' predictions (reported in AECL--9566-2). Some preliminary conclusions and recommendations regarding the field testing are presented

  4. Optical and Near-Infrared Polarimetry for a Highly Dormant Comet 209P/LINEAR

    CERN Document Server

    Kuroda, Daisuke; Watanabe, Makoto; Akitaya, Hiroshi; Takahashi, Jun; Hasegawa, Sunao; Ui, Takahiro; Kanda, Yuka; Takaki, Katsutoshi; Itoh, Ryosuke; Moritani, Yuki; Imai, Masataka; Goda, Shuhei; Takagi, Yuhei; Morihana, Kumiko; Honda, Satoshi; Arai, Akira; Hanayama, Hidekazu; Nagayama, Takahiro; Nogami, Daisaku; Sarugaku, Yuki; Murata, Katsuhiro; Morokuma, Tomoki; Saito, Yoshihiko; Oasa, Yumiko; Sekiguchi, Kazuhiro; Watanabe, Jun-ichi

    2015-01-01

    We conducted an optical and near-infrared polarimetric observation of the highly dormant Jupiter-Family Comet, 209P/LINEAR. Because of its low activity, we were able to determine the linear polarization degrees of the coma dust particles and nucleus independently, that is $P_n$=30.3$^{+1.3}_{-0.9}$% at $\\alpha$=92.2$^\\circ$ and $P_n$=31.0$^{+1.0}_{-0.7}$% at $\\alpha$=99.5$^\\circ$ for the nucleus, and $P_c$=28.8$^{+0.4}_{-0.4}$% at $\\alpha$=92.2$^\\circ$ and 29.6$^{+0.3}_{-0.3}$% at $\\alpha$=99.5$^\\circ$ for the coma. We detected no significant variation in $P$ at the phase angle coverage of 92.2$^\\circ$-99.5$^\\circ$, which may imply that the obtained polarization degrees are nearly at maximum in the phase-polarization curves. By fitting with an empirical function, we obtained the maximum values of linear polarization degrees $P_\\mathrm{max}$=30.8% for the nucleus and $P_\\mathrm{max}$=29.6% for the dust coma. The $P_\\mathrm{max}$ of the dust coma is consistent with those of dust-rich comets. The low geometric a...

  5. 76 FR 8620 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217A, -217C, and -219 Turbofan Engines

    Science.gov (United States)

    2011-02-15

    ...We are superseding an existing airworthiness directive (AD) for Pratt & Whitney (PW) JT8D-209, -217, -217A, -217C, and -219 turbofan engines. That AD currently requires revisions to the engine manufacturer's time limits section (TLS) to include enhanced inspection of selected critical life-limited parts at each piece-part opportunity. This new AD modifies the TLS of the manufacturer's engine......

  6. Fission fragment angular distributions in proton-induced fission of 209 Bi(p,t and 197 Au(p,f

    Directory of Open Access Journals (Sweden)

    S. S.

    2001-12-01

    Full Text Available   The fission fragment angular distributions have been measured for proton-induced fission of 209Bi and 197Au nuclei using surface barrier detectors at several energies between 25 MeV and 30 MeV. The experimental anisotropies are found to be in agreement with the predictions of the Standard Saddle-Point Statistical Model (SSPSM. The fission cross sections of 209Bi 197Au nuclei were also measured and compared with the previous works.

  7. 40 CFR 33.209 - Can EPA re-evaluate the MBE or WBE status of an entity after EPA certifies it to be an MBE or WBE?

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 1 2010-07-01 2010-07-01 false Can EPA re-evaluate the MBE or WBE status of an entity after EPA certifies it to be an MBE or WBE? 33.209 Section 33.209 Protection of... EPA re-evaluate the MBE or WBE status of an entity after EPA certifies it to be an MBE or WBE? (a)...

  8. Isolation and characterization of a cold-resistant PCB209-degrading bacterial strain from river sediment and its application in bioremediation of contaminated soil.

    Science.gov (United States)

    Qiu, Liping; Wang, Hu; Wang, Xuntao

    2016-01-01

    A cold-resistant bacterium (strain QL) that can degrade 2,2',3,3',4,4',5,5',6,6'-decachlorobiphenyl (PCB209) was isolated from Wei-he River sediment. Strain QL was identified as a rod-shaped gram-negative bacterial strain, which was further identified as Comamonas testosteroni. C. testosteroni has never been reported to be capable of degrading PCB209 at low temperatures. In this study, the degradation characteristics showed that strain QL could grow with PCB209 as the sole carbon source at low temperatures (10 ± 0.5 °C). More significantly, strain QL of 40% inoculation volume was able to completely degrade PCB209 in 140 h (initial concentration of PCB209 was 100-500 µg L(-1) at 10 ± 0.5 °C and pH 7-8). The degradation process proceeded with zero-order reaction kinetics. Moreover, both laboratory simulation and real-world field experiments demonstrated that strain QL was effective in practical applications of PCB209 biodegradation in contaminated soil.

  9. A multi-biomarker risk assessment of the impact of brominated flame retardant-decabromodiphenyl ether (BDE209) on the antioxidant system of earthworm Eisenia fetida.

    Science.gov (United States)

    Zhang, Wei; Liu, Kou; Chen, Lin; Chen, Lei; Lin, Kuangfei; Fu, Rongbing

    2014-07-01

    Decabromodiphenyl ether (BDE209) is the major contaminant at e-waste recycling sites (EWRSs), and its potential toxicological effects on terrestrial organisms have received extensive attention. However, the impacts of BDE209 on the antioxidant defense system in terrestrial organisms remain vague. Therefore, indoor incubation tests were performed systematically on control and contaminated soil samples to determine the effects of BDE209 on the antioxidant system of earthworm Eisenia fetida. The results showed that compared to the controls, superoxide dismutase (SOD) activities in all treated groups were elevated significantly after 21 and 28 days exposure; catalase (CAT) activities were much higher in all tests during the entire exposure period; peroxidase (POD) and glutathione-s-transferase (GST) activities generally decreased and indicated contrary response trend; the total antioxidant capacity (T-AOC) after exposure to low level of BDE209 (1 mg kg(-1)) was induced, whereas at 10 and 100 mg kg(-1) concentrations it showed suppression status; electron paramagnetic resonance (EPR) spectra suggested that hydroxyl radicals (OH) in earthworms were significantly induced by BDE209; the changes in malondialdehyde (MDA) contents suggested that reactive oxygen species (ROS) might lead to cellular lipid peroxidation in earthworms. The results of these observations suggested that severe oxidative stress occurred in E. fetida, and it may play an important role in inducing the BDE209 toxicity to earthworms. PMID:25016100

  10. Uptake and depuration kinetics of lead (Pb) and biomarker responses in the earthworm Eisenia fetida after simultaneous exposure to decabromodiphenyl ether (BDE209).

    Science.gov (United States)

    Zhang, Wei; Liu, Kou; Li, Jing; Chen, Lin; Lin, Kuangfei

    2015-03-01

    Lead (Pb) and BDE209 (decabromodiphenyl ether) are the main contaminants at e-waste recycling sites, and their potential toxicological effects on terrestrial organisms have received extensive attention. However, the impact on earthworms of exposure to the two chemicals remains almost unknown. Therefore, indoor incubation tests were performed on control and contaminated soil samples to determine the uptake and toxicity of Pb in the presence of BDE209 to the earthworm Eisenia fetida. The results have demonstrated that the presence of BDE209 facilitated the release of Pb into soil porewater. Compared with exposure to Pb alone, simultaneous exposure to BDE209 significantly enhanced the Pb uptake rate at the level of pGST)] and total antioxidant capacity (T-AOC). The decline trend in antioxidant enzymatic activities and T-AOC might explain an increase in lipid peroxidation reflected by the observed augment in malondialdehyde (MDA) level. Moreover, a biomarker of the lysosomal membrane stability, measured by neutral red retention time (NRRT), was also investigated. The NRRT obviously declined in the joint presence of BDE209, indicating a distinct time-response relationship. The results of these observations have provided a basic understanding of the potential eco-toxicological effects of joint heavy metal and BDE209 exposure on terrestrial invertebrates in a multi-contamination context of ecosystems. PMID:25483371

  11. The effects of early postnatal exposure to a low dose of decabromodiphenyl ether (BDE-209) on serum metabolites in male mice.

    Science.gov (United States)

    Eguchi, Akifumi; Miyaso, Hidenobu; Mori, Chisato

    2016-01-01

    The toxicity of decabromodiphenyl ether (BDE-209) has been reported in several studies. However, there is not much known about the toxicological biomarkers that characterize BDE-209 exposure. In this study, we subcutaneously exposed mice to 0.025 mg/kg/day BDE-209 on postnatal days 1‑5 and sacrificed the animals at 12 weeks of age (day 84). Flow injection analysis and hydrophilic interaction chromatography-triple quadrupole mass spectrometry were used to determine the serum metabolomes of these mice in order to characterize the effects of BDE-209 exposure. Data analysis showed a good separation between control and exposed mice (R(2) = 0.953, Q(2) = 0.728, and ANOVA of the cross‑validated residuals (CV‑ANOVA): P‑value = 0.0317) and 54 metabolites were identified as altered in the exposed animals. These were selected using variable importance (VIP) and loadings scaled by a correlation coefficient criteria and orthogonal partial least squares discriminant analysis (OPLS‑DA). BDE‑209‑exposed mice showed lower levels of long-chain acylcarnitines and citrate cycle-related metabolites, and higher levels of some amino acids, long-chain phospholipids, and short-chain acylcarnitines. The disruption of fatty acid, carbohydrate, and amino acid metabolism observed in the serum metabolome might be related to the previously observed impaired spermatogenesis in mice with early postnatal exposure to a low dose of BDE-209. PMID:27665776

  12. Outcomes of locally advanced prostate cancer: a single institution study of 209 patients in Japan

    Institute of Scientific and Technical Information of China (English)

    Toshihiro Saito; Yasuo Kitamura; Shuichi Komatsubara; Yasuo Matsumoto; Tadashi Sugita; Noboru Hara

    2006-01-01

    Aim: To investigate the outcomes for Asian populations with locally advanced/clinical stage Ⅲ prostate cancer (Pca)treated with currently prevailing modalities. Methods: We reviewed the record of 209 patients with clinical stage Ⅲ Pca, who were treated at Niigata Cancer Center Hospital between 1992 and 2003. Treatment options included hormone therapy-combined radical prostatectomy (RP+HT), hormone therapy-combined external beam irradiation (EBRT+HT) and primary hormone therapy (PHT). Results: The 5- and 10-year overall survival rates were 80.3%and 46.1% in all cohorts, respectively. The survival rates were 87.3% and 66.5% in the RP+HT group, 94.9% and 70.0% in the EBRT+HT group and 66.1% and 17.2% in the PHT group, respectively. A significant survival advantage was found in the EBRT+HT group compared with that in the PHT group (P < 0.0001). Also, the RP+HT group had better survival than the PHT group (P = 0.0107). The 5- and 10-year disease-specific survival rates for all cases were 92.5% and 80.0%, respectively. They were 93.8% and 71.4% in the RP+HT group, 96.6% and 93.6% in the EBRT+HT group and 88.6% and 62.3% in the PHT group, respectively. A survival advantage was found in the EBRT+HT group compared with the PHT group (P = 0.029). No significant difference was found in disease-specific survival between the EBRT+HT and RP+HT groups or between the RP+HT and PHT groups. Conclusion: Although our findings indicate that radiotherapy plus HT has a survival advantage in this stage of Pca, we recommend therapies that take into account the patients' social and medical conditions for Asian men with clinical stage Ⅲ PCa.

  13. CONSTRAINTS ON THE RADIAL VARIATION OF GRAIN GROWTH IN THE AS 209 CIRCUMSTELLAR DISK

    Energy Technology Data Exchange (ETDEWEB)

    Perez, Laura M.; Carpenter, John M.; Isella, Andrea; Ricci, Luca; Sargent, Anneila I. [Astronomy Department, California Institute of Technology, 1200 East California Boulevard, Pasadena, CA 91125 (United States); Chandler, Claire J. [National Radio Astronomy Observatory, P.O. Box O, Socorro, NM 87801 (United States); Andrews, Sean M.; Harris, Robert J. [Harvard-Smithsonian Center for Astrophysics, 60 Garden Street, Cambridge, MA 02138 (United States); Calvet, Nuria [Department of Astronomy, University of Michigan, 830 Dennison Building, 500 Church Street, Ann Arbor, MI 48109 (United States); Corder, Stuartt A. [Joint ALMA Observatory, Av. Alonso de Cordova 3107, Vitacura, Santiago (Chile); Deller, Adam T. [The Netherlands Institute for Radio Astronomy (ASTRON), 7990-AA Dwingeloo (Netherlands); Dullemond, Cornelis P.; Linz, Hendrik [Center for Astronomy, Heidelberg University, Albert Ueberle Str. 2, D-69120 Heidelberg (Germany); Greaves, Jane S. [School of Physics and Astronomy, University of St. Andrews, North Haugh, St Andrews KY16 9SS (United Kingdom); Henning, Thomas [Max-Planck-Institut fuer Astronomie, Koenigstuhl 17, D-69117 Heidelberg (Germany); Kwon, Woojin [Department of Astronomy, University of Illinois, 1002 West Green Street, Urbana, IL 61801 (United States); Lazio, Joseph [Jet Propulsion Laboratory, California Institute of Technology, 4800 Oak Grove Drive, Pasadena, CA 91106 (United States); Mundy, Lee G.; Storm, Shaye [Department of Astronomy, University of Maryland, College Park, MD 20742 (United States); Testi, Leonardo [European Southern Observatory, Karl Schwarzschild Str. 2, D-85748 Garching (Germany); and others

    2012-11-20

    We present dust continuum observations of the protoplanetary disk surrounding the pre-main-sequence star AS 209, spanning more than an order of magnitude in wavelength from 0.88 to 9.8 mm. The disk was observed with subarcsecond angular resolution (0.''2-0.''5) to investigate radial variations in its dust properties. At longer wavelengths, the disk emission structure is notably more compact, providing model-independent evidence for changes in the grain properties across the disk. We find that physical models which reproduce the disk emission require a radial dependence of the dust opacity {kappa}{sub {nu}}. Assuming that the observed wavelength-dependent structure can be attributed to radial variations in the dust opacity spectral index ({beta}), we find that {beta}(R) increases from {beta} < 0.5 at {approx}20 AU to {beta} > 1.5 for R {approx}> 80 AU, inconsistent with a constant value of {beta} across the disk (at the 10{sigma} level). Furthermore, if radial variations of {kappa}{sub {nu}} are caused by particle growth, we find that the maximum size of the particle-size distribution (a{sub max}) increases from submillimeter-sized grains in the outer disk (R {approx}> 70 AU) to millimeter- and centimeter-sized grains in the inner disk regions (R {approx}< 70 AU). We compare our observational constraint on a{sub max}(R) with predictions from physical models of dust evolution in protoplanetary disks. For the dust composition and particle-size distribution investigated here, our observational constraints on a{sub max}(R) are consistent with models where the maximum grain size is limited by radial drift.

  14. Experimental Cross Sections for Reactions of Heavy Ions and 208Pb, 209Bi, 238U, and 248Cm Targets

    Energy Technology Data Exchange (ETDEWEB)

    Patin, Joshua B.

    2002-05-24

    The study of the reactions between heavy ions and {sup 208}Pb, {sup 209}Bi, {sup 238}U, and {sup 248} Cm targets was performed to look at the differences between the cross sections of hot and cold fusion reactions. Experimental cross sections were compared with predictions from statistical computer codes to evaluate the effectiveness of the computer code in predicting production cross sections. Hot fusion reactions were studied with the MG system, catcher foil techniques and the Berkeley Gas-filled Separator (BGS). 3n- and 4n-exit channel production cross sections were obtained for the {sup 238}U({sup 18}O,xn){sup 256-x}Fm, {sup 238}U({sup 22}Ne,xn){sup 260-x}No, and {sup 248}Cm({sup 15}N,xn){sup 263-x}Lr reactions and are similar to previous experimental results. The experimental cross sections were accurately modeled by the predictions of the HIVAP code using the Reisdorf and Schaedel parameters and are consistent with the existing systematics of 4n exit channel reaction products. Cold fusion reactions were examined using the BGS. The {sup 208}Pb({sup 48}Ca,xn){sup 256-x}No, {sup 208}Pb({sup 50}Ti,xn){sup 258-x}Rf, {sup 208}Pb({sup 51}V,xn){sup 259-x}Db, {sup 209}Bi({sup 50}Ti,xn){sup 259-x}Db, and {sup 209}Bi({sup 51}V,xn){sup 260-x}Sg reactions were studied. The experimental production cross sections are in agreement with the results observed in previous experiments. It was necessary to slightly alter the Reisdorf and Schaedel parameters for use in the HIVAP code in order to more accurately model the experimental data. The cold fusion experimental results are in agreement with current 1n- and 2n-exit channel systematics.

  15. Polymorphisms in the feline TNFA and CD209 genes are associated with the outcome of feline coronavirus infection.

    Science.gov (United States)

    Wang, Ying-Ting; Hsieh, Li-En; Dai, Yu-Rou; Chueh, Ling-Ling

    2014-01-01

    Feline infectious peritonitis (FIP), caused by feline coronavirus (FCoV) infection, is a highly lethal disease without effective therapy and prevention. With an immune-mediated disease entity, host genetic variant was suggested to influence the occurrence of FIP. This study aimed at evaluating cytokine-associated single nucleotide polymorphisms (SNPs), i.e., tumor necrosis factor alpha (TNF-α), receptor-associated SNPs, i.e., C-type lectin DC-SIGN (CD209), and the five FIP-associated SNPs identified from Birman cats of USA and Denmark origins and their associations with the outcome of FCoV infection in 71 FIP cats and 93 FCoV infected non-FIP cats in a genetically more diverse cat populations. A promoter variant, fTNFA - 421 T, was found to be a disease-resistance allele. One SNP was identified in the extracellular domain (ECD) of fCD209 at position +1900, a G to A substitution, and the A allele was associated with FIP susceptibility. Three SNPs located in the introns of fCD209, at positions +2276, +2392, and +2713, were identified to be associated with the outcome of FCoV infection, with statistical relevance. In contrast, among the five Birman FIP cat-associated SNPs, no genotype or allele showed significant differences between our FIP and non-FIP groups. As disease resistance is multifactorial and several other host genes could involve in the development of FIP, the five genetic traits identified in this study should facilitate in the future breeding of the disease-resistant animal to reduce the occurrence of cats succumbing to FIP. PMID:25512064

  16. Frequency of SNP -336A/G in the promoter region of CD209 in a population from northeastern Brazil.

    Science.gov (United States)

    Costa, P N; Ferreira-Fernandes, H; de Oliveira, J S; Pereira, A C T C; Pinto, G R; Ferreira, G P

    2015-08-14

    Dendritic cells (DCs) mediate the initiation of the immune response against a variety of pathogens. The DC-SIGN receptor is encoded by the gene CD209 and is expressed on the surface of DCs. It binds to mannose-rich carbohydrates and enables the recognition of bacteria, fungi, parasites, and viruses. SNP -336A/G in the promoter region of CD209 influences the expression of the DC-SIGN receptor. Several studies have associated this SNP with an increased susceptibility to infectious diseases and the development of more severe forms of disease. Therefore, the aim of this study was to determine the prevalence of SNP -336A/G in a population from northeastern Brazil. We analyzed 181 individuals from the general population of Parnaíba, Piauí, Brazil, of which 37% were men and 63% were women. SNP -336A/G was detected by polymerase chain reaction and treatment with the restriction enzyme MscI and visualized by electrophoresis on an 8% polyacrylamide gel stained with silver nitrate. Of the individuals analyzed, 116 (64.1%) were homozygous AA, 57 (31.5%) were heterozygous (AG), and 8 (4.4%) were homozygous GG. The allele frequency of -336G was 20.2%. Genotype frequencies were in Hardy-Weinberg equilibrium. To the best of our knowledge, this is the first report to describe the frequency of the CD209 SNP -336A/G in a population in the State of Piauí. Further studies are needed to determine the relationship between this SNP and the vulnerability of this population to major infectious diseases.

  17. Polymorphisms in the feline TNFA and CD209 genes are associated with the outcome of feline coronavirus infection.

    Science.gov (United States)

    Wang, Ying-Ting; Hsieh, Li-En; Dai, Yu-Rou; Chueh, Ling-Ling

    2014-12-16

    Feline infectious peritonitis (FIP), caused by feline coronavirus (FCoV) infection, is a highly lethal disease without effective therapy and prevention. With an immune-mediated disease entity, host genetic variant was suggested to influence the occurrence of FIP. This study aimed at evaluating cytokine-associated single nucleotide polymorphisms (SNPs), i.e., tumor necrosis factor alpha (TNF-α), receptor-associated SNPs, i.e., C-type lectin DC-SIGN (CD209), and the five FIP-associated SNPs identified from Birman cats of USA and Denmark origins and their associations with the outcome of FCoV infection in 71 FIP cats and 93 FCoV infected non-FIP cats in a genetically more diverse cat populations. A promoter variant, fTNFA - 421 T, was found to be a disease-resistance allele. One SNP was identified in the extracellular domain (ECD) of fCD209 at position +1900, a G to A substitution, and the A allele was associated with FIP susceptibility. Three SNPs located in the introns of fCD209, at positions +2276, +2392, and +2713, were identified to be associated with the outcome of FCoV infection, with statistical relevance. In contrast, among the five Birman FIP cat-associated SNPs, no genotype or allele showed significant differences between our FIP and non-FIP groups. As disease resistance is multifactorial and several other host genes could involve in the development of FIP, the five genetic traits identified in this study should facilitate in the future breeding of the disease-resistant animal to reduce the occurrence of cats succumbing to FIP.

  18. Evaluation of enhancement patterns using three-dimensional dynamic contrast-enhanced MR imaging in 209 cases of breast cancer

    International Nuclear Information System (INIS)

    The purpose of this study was to evaluate contrast-enhanced patterns using three-dimensional (3D) dynamic MR imaging in 209 cases of breast cancer. Three-dimensional dynamic imaging of the breast (1.5-T scanner) was performed in 755 cases. Of 227 breast carcinomas, 209 cases that were histologically confirmed were enrolled in this study. The histological diagnoses included ductal carcinoma in situ (DCIS) (n=12), invasive ductal carcinoma (n=176), mucinous carcinoma (n=10), meduliary carcinoma (n=4), invasive lobular carcinoma (n=6), and other (n=1). Tumor size was a mean 24.6 mm in diameter (range, 7-110 mm), including 110 cases of small breast carcinomas (≤2 cm). The contrast-enhancement pattern was analyzed from the early phase of 3D-MRI and the post-contrast T1-weighted spin echo (SE) image acquired before the delayed phase of 3D-MRI. The type of peripheral enhancement (PE) was evaluated on the early and delayed phases of 3D-MRI. These enhancement patterns were also compared with the histological findings of small breast carcinomas. The sensitivity of the 209 cases of breast carcinoma was 99% (207/209) on 3D dynamic MRI. Two hundred six cases (98.6%), including all DCIS, showed strong enhancement on the early phase of 3D MRI. An increased washout pattern showing signal intensity lower than that of fat on post-contrast T1-weighted imaging was noted in 201 cases (96.1%), of which 179 cases (85.6%) showed washout patterns. PE was identified in 63 cases (30.4%) and in 35 of 110 cases of small breast carcinoma (31.8%). Delayed PE following central washout was noted in 65% of 63 cases and 71.4% of 35 cases of small breast carcinoma. Delayed PE was well correlated with marginal fibrosis. Three-dimensional dynamic MRI of the breast was highly sensitive for breast carcinoma. Delayed PE following central washout was considered a specific finding of breast carcinoma. It is important to understand the enhancement patterns of 3D dynamic MRI for excellent specificity of

  19. Inclusive Jet Production in Photon-Photon Collisions at $\\sqrt{s_{ee}}$ from 189 to 209 GeV

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Anagnostou, G; Anderson, K J; Asai, S; Axen, D; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, R J; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, S; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brown, R M; Burckhart, H J; Campana, S; Capiluppi, P; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; Dallavalle, G M; de Roeck, A; De Wolf, E A; Desch, K; Dienes, B; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, F; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, J; Gruwé, M; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Herten, G; Heuer, R D; Hill, J C; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanzaki, J; Karlen, D; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krasznahorkay, A; Krieger, P; Von Krogh, J; Kühl, T; Kupper, M; Lafferty, G D; Landsman, H; Lanske, D; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Mashimo, T; Mättig, P; McKenna, J; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Pooth, O; Przybycien, M; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rossi, A M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schiecks, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, J; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2008-01-01

    Inclusive jet production (e+e- -> e+e- +jet+X) is studied in collisions of quasi-real photons radiated by the LEP beams at e+e- centre-of-mass energies sqrt see from 189 to 209 GeV. Jets are reconstructed using the kp jet algorithm. The inclusive differential cross-section is measured as a function of the jet transverse momentum, ptjet, in the range 5

  20. Determination of the {sup 209}Bi(n,{gamma}){sup 210}Bi and {sup 209}Bi(n,{gamma}){sup 210m,g}Bi reaction cross sections in a cold neutron beam

    Energy Technology Data Exchange (ETDEWEB)

    Borella, A. [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, B-2440 Geel (Belgium); SCK-CEN, Boeretang 200, B-2400 Mol (Belgium); Belgya, T. [Institute of Isotope, Hungarian Academy of Sciences, POB 77, H-1525 Budapest (Hungary); Kopecky, S. [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, B-2440 Geel (Belgium); Gunsing, F. [CEA/Saclay, DSM/Irfu, F-91191 Gif-sur-Yvette (France); Moxon, M. [Hyde Copse 3, Marcham (United Kingdom); Rejmund, M. [GANIL, F-14076 Caen (France); Schillebeeckx, P., E-mail: peter.schillebeeckx@ec.europa.e [European Commission, Joint Research Centre, Institute for Reference Materials and Measurements, B-2440 Geel (Belgium); Szentmiklosi, L. [Institute of Isotope, Hungarian Academy of Sciences, POB 77, H-1525 Budapest (Hungary)

    2011-01-15

    Gamma-ray transitions following neutron capture in {sup 209}Bi have been studied at the cold neutron beam facility of the Budapest Neutron Centre. Measurements have been performed using a coaxial HPGe detector with Compton suppression. Partial capture cross sections at a velocity of 2200 m/s (or a neutron energy of 25.3 meV) have been deduced relatively to the one for the 4055 keV transition after thermal neutron capture in {sup 209}Bi. This partial cross section of (8.07 {+-} 0.14) mb has in turn been obtained from measurements with a bismuth nitrate target relatively to the cross section for the 1884 keV transition after thermal neutron capture in {sup 14}N. Shell model calculations have been performed to deduce the half-life of the 3rd excited state at 320 keV and to assign the M1 multipolarity of the 320 keV transition to the ground state. Lower limits of (21.4 {+-} 0.8) mb and (18.2 {+-} 0.7) mb for the cross sections to the ground state and to the isomeric state, respectively, have been deduced from the data for the gamma rays feeding these states. The results obtained in this work are in good agreement with experimental data reported in the literature. The thermal total capture cross section has been compared with the contribution due to observed s-wave resonances.

  1. Dermal-type macrophages expressing CD209/DC-SIGN show inherent resistance to dengue virus growth.

    Directory of Open Access Journals (Sweden)

    Wing-Hong Kwan

    Full Text Available BACKGROUND: An important question in dengue pathogenesis is the identity of immune cells involved in the control of dengue virus infection at the site of the mosquito bite. There is evidence that infection of immature myeloid dendritic cells plays a crucial role in dengue pathogenesis and that the interaction of the viral envelope E glycoprotein with CD209/DC-SIGN is a key element for their productive infection. Dermal macrophages express CD209, yet little is known about their role in dengue virus infection. METHODS AND FINDINGS: Here, we showed that dermal macrophages bound recombinant envelope E glycoprotein fused to green fluorescent protein. Because dermal macrophages stain for IL-10 in situ, we generated dermal-type macrophages from monocytes in the presence of IL-10 to study their infection by dengue virus. The macrophages were able to internalize the virus, but progeny virus production was undetectable in the infected cells. In addition, no IFN-alpha was produced in response to the virus. The inability of dengue virus to grow in the macrophages was attributable to accumulation of internalized virus particles into poorly-acidified phagosomes. CONCLUSIONS: Aborting infection by viral sequestration in early phagosomes would present a novel means to curb infection of enveloped virus and may constitute a prime defense system to prevent dengue virus spread shortly after the bite of the infected mosquito.

  2. When Comets Get Old: A Synthesis of Comet and Meteor Observations of the Low Activity Comet 209P/LINEAR

    CERN Document Server

    Ye, Quan-Zhi; Brown, Peter G; Campbell-Brown, Margaret D; Pokorný, Petr; Wiegert, Paul A; Gao, Xing

    2015-01-01

    It is speculated that some weakly active comets may be transitional objects between active and dormant comets. These objects are at a unique stage of the evolution of cometary nuclei, as they are still identifiable as active comets, in contrast to inactive comets that are observationally indistinguishable from low albedo asteroids. In this paper, we present a synthesis of comet and meteor observations of Jupiter-family comet 209P/LINEAR, one of the most weakly active comets recorded to-date. Images taken by the Xingming 0.35-m telescope and the Gemini Flamingo-2 camera are modeled by a Monte Carlo dust model, which yields a low dust ejection speed ($1/10$ of that of moderately active comets), dominance of large dust grains, and a low dust production of $0.4~\\mathrm{kg \\cdot s^{-1}}$ at 19~d after the 2014 perihelion passage. We also find a reddish nucleus of 209P/LINEAR that is similar to D-type asteroids and most Trojan asteroids. Meteor observations with the Canadian Meteor Orbit Radar (CMOR), coupled with ...

  3. Evaluation of MS-209, a novel multidrug-resistance-reversing agent, in tumour-bearing mice by technetium-99m-MIBI imaging

    Energy Technology Data Exchange (ETDEWEB)

    Tatsumi, Mitsuaki; Nishimura, Tsunehiko [Division of Tracer Kinetics, Osaka University Graduate School of Medicine (Japan); Tsuruo, Takashi [Department of Chemical Biology, Institute of Molecular and Cellular Biosciences, University of Tokyo (Japan)

    2002-03-01

    MS-209 is a newly synthesised multidrug-resistance (MDR)-reversing agent with few side-effects. In this study, we evaluated the effect of MS-209 on P-glycoprotein (Pgp)-positive tumours in mice by means of technetium-99m methoxyisobutylisonitrile (MIBI) imaging. Mice received Pgp-negative KB-3-1 or Pgp-positive KB-C1 cell xenografts. KB-3-1-bearing mice were administered 0 or 100 mg/kg of MS-209 (groups S0 and S100, respectively), and KB-C1-bearing mice 0, 50, 100 or 200 mg/kg (groups R0, R50, R100 and R200, respectively), 30 min before imaging studies. Dynamic {sup 99m}Tc-MIBI images were acquired for 30 min, followed by biodistribution studies. Washout of {sup 99m}Tc-MIBI from the tumours was faster in group R0 than in group S0 on visual analysis, and the washout half-time estimated by region of interest analysis was shorter in group R0 than in group S0. Biodistribution studies revealed that {sup 99m}Tc-MIBI accumulation in tumours (expressed as %ID/g) was also lower in group R0 than in group S0. MS-209 delayed the {sup 99m}Tc-MIBI washout from KB-C1 tumours. Washout half-time was longer in groups R50, R100 and R200 than in group R0. A higher %ID/g was observed in groups R100 and R200 than in group R0. In KB-3-1 tumours, MS-209 had no effect on the washout half-time or the %ID/g. This study demonstrated that MS-209 increases the {sup 99m}Tc-MIBI accumulation in Pgp-positive tumours. The MDR-reversing effect of MS-209 could be effectively evaluated with {sup 99m}Tc-MIBI visually and non-invasively in vivo. {sup 99m}Tc-MIBI imaging with MS-209 prior to chemotherapy should contribute significantly to the treatment strategy in patients with multidrug-resistant tumours. (orig.)

  4. 调Q开关Nd:YAG染料激光治疗太田痣209例疗效观察%Clinical Effect of Q- switched Nd: YAG Dye Laser Surgery in Treatment of 209 Patients with Nevus of Ota

    Institute of Scientific and Technical Information of China (English)

    高宇; 叶信海

    2001-01-01

    目的:评估调Q开关Nd:YAG染料激光治疗太田痣临床疗效.方法:应用调Q开关Nd:YAG染料激光治疗209例太田痣.波长700 nm,脉宽30 us,能量密度5.6 J/cm2.每次治疗后色素未消退者,间隔3~6月再行下一次治疗.结果:调Q开关Nd:YAG染料激光治疗4~6次后,192例效果极显著,17例效果显著,治疗后患者均无疤痕.结论:调Q开关Nd:YAG染料激光治疗太田痣效果满意、安全.

  5. Complete and incomplete fusion cross sections for 6Li+209Bi reaction in multi-body classical molecular dynamical model

    International Nuclear Information System (INIS)

    Using the multi-body Classical Molecular Dynamics simulation of 6Li+209Bi reaction it is shown that: (i) the breakup of a projectile fragment near the barrier leads to substantial increase in the ICF probabilities; (ii) the expected increase in σCF on relaxation of the rigid-body (RB) constraint on the projectile is compensated by reduction in the flux leading to CF, due to ICF events; (iii) the breakup probability increases with ECM and, for given ECM it also increases as b increases and peaks around some b>0, while cross sections σCF and σTF were calculated for b=0 only Therefore, we present the results of σCF (Complete Fusion) and σTF (Total Fusion) calculations which are obtained at critical impact parameter, bcr, where many ICF channels open up and compare with the calculations performed at b=0 only, where only few ICF channels open up

  6. Photon Events with Missing Energy in $e^{+}e^{-}$ Collisions at $\\sqrt{s}$ = 130 to 209 GeV

    CERN Document Server

    Abdallah, J; Adam, W; Adzic, P; Albrecht, T; Alderweireld, T; Alemany-Fernandez, R; Allmendinger, T; Allport, P P; Amaldi, Ugo; Amapane, N; Amato, S; Anashkin, E; Andreazza, A; Andringa, S; Anjos, N; Antilogus, P; Apel, W D; Arnoud, Y; Ask, S; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Ballestrero, A; Bambade, P; Barbier, R; Bardin, Dimitri Yuri; Barker, G J; Baroncelli, A; Battaglia, Marco; Baubillier, M; Becks, K H; Begalli, M; Behrmann, A; Ben-Haim, E; Benekos, N C; Benvenuti, Alberto C; Bérat, C; Berggren, M; Berntzon, L; Bertrand, D; Besançon, M; Besson, N; Bloch, D; Blom, M; Bluj, M; Bonesini, M; Boonekamp, M; Booth, P S L; Borisov, G; Botner, O; Bouquet, B; Bowcock, T J V; Boyko, I; Bracko, M; Brenner, R; Brodet, E; Brückman, P; Brunet, J M; Bugge, L; Buschmann, P; Calvi, M; Camporesi, T; Canale, V; Carena, F; Castro, N; Cavallo, F R; Chapkin, M M; Charpentier, P; Checchia, P; Chierici, R; Shlyapnikov, P; Chudoba, J; Chung, S U; Cieslik, K; Collins, P; Contri, R; Cosme, G; Cossutti, F; Costa, M J; Crennell, D J; Cuevas-Maestro, J; D'Hondt, J; Dalmau, J; Da Silva, T; Da Silva, W; Della Ricca, G; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Maria, N; De Min, A; De Paula, L S; Di Ciaccio, L; Di Simone, A; Doroba, K; Drees, J; Dris, M; Eigen, G; Ekelöf, T J C; Ellert, M; Elsing, M; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Feindt, M; Fernández, J; Ferrer, A; Ferro, F; Flagmeyer, U; Föth, H; Fokitis, E; Fulda-Quenzer, F; Fuster, J A; Gandelman, M; García, C; Gavillet, P; Gazis, E N; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; Graziani, E; Grosdidier, G; Grzelak, K; Guy, J; Haag, C; Hallgren, A; Hamacher, K; Hamilton, K; Haug, S; Hauler, F; Hedberg, V; Hennecke, M; Herr, H; Hoffman, J; Holmgren, S O; Holt, P J; Houlden, M A; Hultqvist, K; Jackson, J N; Jarlskog, G; Jarry, P; Jeans, D; Johansson, E K; Johansson, P D; Jonsson, P; Joram, C; Jungermann, L; Kapusta, F; Katsanevas, S; Katsoufis, E C; Kernel, G; Kersevan, B P; Kerzel, U; Kiiskinen, A P; King, B T; Kjaer, N J; Kluit, P; Kokkinias, P; Kourkoumelis, C; Kuznetsov, O; Krumshtein, Z; Kucharczyk, M; Lamsa, J; Leder, G; Ledroit, F; Leinonen, L; Leitner, R; Lemonne, J; Lepeltier, V; Lesiak, T; Liebig, W; Liko, D; Lipniacka, A; Lopes, J H; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Malek, A; Maltezos, S; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Masik, J; Mastroyiannopoulos, N; Matorras, F; Matteuzzi, C; Mazzucato, F; Mazzucato, M; McNulty, R; Meroni, C; Migliore, E; Mitaroff, W A; Mjörnmark, U; Moa, T; Moch, M; Mönig, K; Monge, R; Montenegro, J; Moraes, D; Moreno, S; Morettini, P; Müller, U; Münich, K; Mulders, M; Mundim, L; Murray, W; Muryn, B; Myatt, G; Myklebust, T; Nassiakou, M; Navarria, Francesco Luigi; Nawrocki, K; Nicolaidou, R; Nikolenko, M; Oblakowska-Mucha, A; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, R; Österberg, K; Ouraou, A; Oyanguren, A; Paganoni, M; Paiano, S; Palacios, J P; Palka, H; Papadopoulou, T D; Pape, L; Parkes, C; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Peralta, L; Perepelitsa, V F; Perrotta, A; Petrolini, A; Piedra, J; Pieri, L; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Poireau, V; Pol, M E; Polok, G; Pozdnyakov, V; Pukhaeva, N; Pullia, Antonio; Rames, J; Read, A; Rebecchi, P; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Richard, F; Rídky, J; Rivero, M; Rodríguez, D; Romero, A; Ronchese, P; Roudeau, P; Rovelli, T; Ruhlmann-Kleider, V; Ryabtchikov, D; Sadovskii, A; Salmi, L; Salt, J; Sander, C; Savoy-Navarro, A; Schwickerath, U; Segar, A; Sekulin, R L; Siebel, M; Sissakian, A N; Smadja, G; Smirnova, O G; Sokolov, A; Sopczak, A; Sosnowski, R; Spassoff, Tz; Stanitzki, M; Stocchi, A; Strauss, J; Stugu, B; Szczekowski, M; Szeptycka, M; Szumlak, T; Tabarelli de Fatis, T; Taffard, A C; Tegenfeldt, F; Timmermans, J; Tkatchev, L G; Tobin, M; Todorovova, S; Tomé, B; Tonazzo, A; Tortosa, P; Travnicek, P; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M L; Tyapkin, I A; Tyapkin, P; Tzamarias, S; Uvarov, V; Valenti, G; van Dam, P; Van Eldik, J; Van Lysebetten, A; Van Remortel, N; Van Vulpen, I; Vegni, G; Veloso, F; Venus, W A; Verdier, P; Verzi, V; Vilanova, D; Vitale, L; Vrba, V; Wahlen, H; Washbrook, A J; Weiser, C; Wicke, D; Wickens, J H; Wilkinson, G; Winter, M; Witek, M; Yushchenko, O P; Zalewska-Bak, A; Zalewski, P; Zavrtanik, D; Zhuravlov, V; Zimin, N I; Zintchenko, A; Zupan, M

    2005-01-01

    The production of single- and multi-photon events has been studied in the reaction e+e- -> gamma (gamma) + invisible particles. The data collected with the DELPHI detector during the years 1999 and 2000 at centre-of-mass energies between 191 GeV and 209 GeV was combined with earlier data to search for phenomena beyond the Standard Model. The measured number of light neutrino families was consistent with three and the absence of an excess of events beyond that predicted by the Standard Model processes was used to set limits on new physics. Both model-independent searches and searches for new processes predicted by supersymmetric and extra-dimensional models have been made. Limits on new non-standard model interactions between neutrinos and electrons were also determined.

  7. Study of viscosity on the fission dynamics of the excited nuclei 228U produced in 19F + 209Bi reactions

    International Nuclear Information System (INIS)

    A two-dimensional (2D) dynamical model based on Langevin equations was applied to study the fission dynamics of the compound nuclei 228U produced in 19F + 209Bi reactions at intermediate excitation energies. The distance between the centers of masses of the future fission fragments was used as the first dimension and the projection of the total spin of the compound nucleus onto the symmetry axis, K, was considered as the second dimension in Langevin dynamical calculations. The magnitude of post-saddle friction strength was inferred by fitting measured data on the average pre-scission neutron multiplicity for 228U. It was shown that the results of calculations are in good agreement with the experimental data by using values of the post-saddle friction equal to 6–8 × 1021s-1. (author)

  8. Studies of QCD at $e^{+}e^{-}$ Centre-of-Mass Energies between 91 and 209 GeV

    CERN Document Server

    Heister, A; Barate, R; Brunelière, R; De Bonis, I; Décamp, D; Goy, C; Jézéquel, S; Lees, J P; Martin, F; Merle, E; Minard, M N; Pietrzyk, B; Trocmé, B; Bravo, S; Casado, M P; Chmeissani, M; Crespo, J M; Fernández, E; Fernández-Bosman, M; Garrido, L; Martínez, M; Pacheco, A; Ruiz, H; Colaleo, A; Creanza, D; De Filippis, N; De Palma, M; Iaselli, G; Maggi, G; Maggi, M; Nuzzo, S; Ranieri, A; Raso, G; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Tricomi, A; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Abbaneo, D; Barklow, T; Buchmüller, O L; Cattaneo, M; Clerbaux, B; Drevermann, H; Forty, R W; Frank, M; Gianotti, F; Hansen, J B; Harvey, J; Hutchcroft, D E; Janot, P; Jost, B; Kado, M; Mato, P; Moutoussi, A; Ranjard, F; Rolandi, Luigi; Schlatter, W D; Sguazzoni, G; Teubert, F; Valassi, Andrea; Videau, I; Badaud, F; Dessagne, S; Falvard, A; Fayolle, D; Gay, P; Jousset, J; Michel, B; Monteil, S; Pallin, D; Pascolo, J M; Perret, P; Hansen, J D; Hansen, J R; Hansen, P H; Kraan, A C; Nilsson, B S; Kyriakis, A; Markou, C; Simopoulou, Errietta; Vayaki, Anna; Zachariadou, K; Blondel, A; Brient, J C; Machefert, F P; Rougé, A; Videau, H L; Ciulli, V; Focardi, E; Parrini, G; Antonelli, A; Antonelli, M; Bencivenni, G; Bossi, F; Capon, G; Cerutti, F; Chiarella, V; Laurelli, P; Mannocchi, G; Murtas, G P; Passalacqua, L; Kennedy, J; Lynch, J G; Negus, P; O'Shea, V; Thompson, A S; Wasserbaech, S R; Cavanaugh, R J; Dhamotharan, S; Geweniger, C; Hanke, P; Hepp, V; Kluge, E E; Putzer, A; Stenzel, H; Tittel, K; Wunsch, M; Beuselinck, R; Cameron, W; Davies, G; Dornan, P J; Girone, M; Hill, R D; Marinelli, N; Nowell, J; Rutherford, S A; Sedgbeer, J K; Thompson, J C; White, R; Ghete, V M; Girtler, P; Kneringer, E; Kuhn, D; Rudolph, G; Bouhova-Thacker, E; Bowdery, C K; Clarke, D P; Ellis, G; Finch, A J; Foster, F; Hughes, G; Jones, R W L; Pearson, M R; Robertson, N A; Smizanska, M; van der Aa, O; Delaere, C; Leibenguth, G; Lemaître, V; Blumenschein, U; Hölldorfer, F; Jakobs, K; Kayser, F; Kleinknecht, K; Müller, A S; Renk, B; Sander, H G; Schmeling, S; Wachsmuth, H W; Zeitnitz, C; Ziegler, T; Bonissent, A; Coyle, P; Curtil, C; Ealet, A; Fouchez, D; Payre, P; Tilquin, A; Ragusa, F; David, A; Dietl, H; Ganis, G; Hüttmann, K; Lütjens, G; Männer, W; Moser, H G; Settles, Ronald; Villegas, M; Wolf, G; Boucrot, J; Callot, O; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Jacholkowska, A; Serin, L; Veillet, J J; Azzurri, P; Bagliesi, G; Boccali, T; Foà, L; Giammanco, A; Giassi, A; Ligabue, F; Messineo, A; Palla, F; Sanguinetti, G; Sciabà, A; Spagnolo, P; Tenchini, R; Venturi, A; Verdini, P G; Awunor, O; Blair, G A; Cowan, G; García-Bellido, A; Green, M G; Medcalf, T; Misiejuk, A; Strong, J A; Teixeira-Dias, P; Clifft, R W; Edgecock, T R; Norton, P R; Tomalin, I R; Ward, J J; Bloch-Devaux, B; Boumediene, D E; Colas, P; Fabbro, B; Lançon, E; Lemaire, M C; Locci, E; Pérez, P; Rander, J; Tuchming, B; Vallage, B; Litke, A M; Taylor, G; Booth, C N; Cartwright, S; Combley, F; Hodgson, P N; Lehto, M H; Thompson, L F; Böhrer, A; Brandt, S; Grupen, C; Hess, J; Ngac, A; Prange, G; Borean, C; Giannini, G; He, H; Pütz, J; Rothberg, J E; Armstrong, S R; Berkelman, K; Cranmer, K; Ferguson, D P S; Gao, Y; González, S; Hayes, O J; Hu, H; Jin, S; Kile, J; McNamara, P A; Nielsen, J; Pan, Y B; Von Wimmersperg-Töller, J H; Wiedenmann, W; Wu, J; Wu Sau Lan; Wu, X; Zobernig, G; Dissertori, G

    2004-01-01

    The hadronic final states observed with the ALEPH detector at LEP in e+e- annihilation are analysed using 730 pb-1 of data collected between 91 and 209 GeV in the framework of QCD. In particular event-shape variables and inclusive charged particle spectra are measured. The energy evolution of quantities derived from these measurements is compared to analytic QCD predictions. The mean charged particle multiplicity, the charged particle momentum spectrum and its peak position are compared to predictions of the modified-leading-logarithmic approximation. The strong coupling constant alpha_s is determined from a fit of the QCD prediction to distributions of six event-shape variables at eight centre-of-mass energies. A study of non-perturbative power law corrections is presented

  9. Shelf Edge Exchange Processes: 2, SEEP2-09, R/V ENDEAVOR cruise 193: Hydrographic data report

    Energy Technology Data Exchange (ETDEWEB)

    Behrens, W.J.; Wilson, C.; Flagg, C.N.; Wallace, D.W.R.; Wilke, R.J.; Wyman, K.D.

    1990-01-01

    The R/V ENDEAVOR cruise 193, SEEP2-09, took place from 17--23 March 1989 and focused primarily on biological processes in the SEEP2 area. Mooring 1 was recovered and re-deployed and a replacement for mooring 4 was deployed. A 24 hour time series was conducted at mooring 1 to study primary and secondary production. The time series involved sampling nutrients, dissolved oxygen, chlorophyll {und a}, zooplankton abundance and distribution and fecal pellet production. Experiments to estimate grazing rates the fecal pellet production of the dominant copepods were also done. MOCNESS tows and box core samples were also taken during the cruise. Sediment and zooplankton data are not reported here. During this cruise 46 CTD casts were made measuring pressure, temperature, conductivity, dissolved oxygen, fluorescence and light transmission. Discrete samples were taken in rosette-mounted Niskin bottles and analyzed for concentration of nutrients, chlorophyll {und a}, dissolved oxygen, and particulate organic carbon and nitrogen.

  10. $Z\\gamma*$ production in $e^+ e^-$ interactions at $\\sqrt{s}$ = 183 - 209 GeV

    CERN Document Server

    Abdallah, J; Adam, W; Adzic, P; Albrecht, T; Alemany-Fernandez, R; Allmendinger, T; Allport, P P; Amaldi, Ugo; Amapane, N; Amato, S; Anashkin, E; Andreazza, A; Andringa, S; Anjos, N; Antilogus, P; Apel, W D; Arnoud, Y; Ask, S; Åsman, B; Augustin, J E; Augustinus, A; Baillon, P; Ballestrero, A; Bambade, P; Barbier, R; Bardin, D; Barker, G J; Baroncelli, A; Battaglia, M; Baubillier, M; Becks, K H; Begalli, M; Behrmann, A; Ben-Haim, E; Benekos, N; Benvenuti, A; Bérat, C; Berggren, M; Bertrand, D; Besançon, M; Besson, N; Bloch, D; Blom, M; Bluj, M; Bonesini, M; Boonekamp, M; Booth, P S L; Borisov, G; Botner, O; Bouquet, B; Bowcock, T J V; Boyko, I; Bracko, M; Brenner, R; Brodet, E; Brückman, P; Brunet, J M; Buschbeck, B; Buschmann, P; Calvi, M; Camporesi, T; Canale, V; Carena, F; Castro, N; Cavallo, F; Chapkin, M; Charpentier, P; Checchia, P; Chierici, R; Chliapnikov, P V; Chudoba, J; Chung, S U; Cieslik, K; Collins, P; Contri, R; Cosme, G; Cossutti, F; Costa, M J; Crennell, D J; Cuevas-Maestro, J; D'Hondt, J; Da Silva, T; Da Silva, W; Della Ricca, G; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Maria, N; De Min, A; De Paula, L; Di Ciaccio, L; Di Simone, A; Doroba, K; Drees, J; Eigen, G; Ekelöf, T J C; Ellert, M; Elsing, M; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Feindt, M; Fernández, J; Ferrer, A; Ferro, F; Flagmeyer, U; Föth, H; Fokitis, E; Fulda-Quenzer, F; Fuster, J; Gandelman, M; García, C; Gavillet, P; Gazis, E; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; Graziani, E; Grosdidier, G; Grzelak, K; Guy, J; Haag, C; Hallgren, A; Hamacher, K; Hamilton, K; Haug, S; Hauler, F; Hedberg, V; Hennecke, M; Herr, H; Hoffman, J; Holmgren, S O; Holt, P J; Houlden, M A; Jackson, J N; Jarlskog, G; Jarry, P; Jeans, D; Johansson, E K; Jonsson, P; Joram, C; Jungermann, L; Kapusta, F; Katsanevas, S; Kokkinias, P; Leinonen, L; Katsoufis, E; Kernel, G; Kersevan, B P; Krumshtein, Z; Lesiak, T; Kerzel, U; Liebig, W; King, B T; Lamsa, J; Liko, D; Kjaer, N J; Leder, G; Kluit, P; Kourkoumelis, C; Leitner, R; Kuznetsov, O; Kucharczyk, M; Ledroit, F; Lopes, J H; Lemonne, J; Lepeltier, V; Lipniacka, A; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Malek, A; Maltezos, S; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou12, A; Martínez-Rivero, C; Masik, J; Mastroyiannopoulos, N; Matorras, F; Matteuzzi, C; Mazzucato, F; Mazzucato, M; McNulty, R; Meroni, C; Migliore, E; Mitaroff, W A; Mjörnmark, U; Moa, T; Moch, M; Mönig, K; Monge, R; Montenegro, J; Moraes, D; Moreno, S; Morettini, P; Müller, U; Münich, K; Mulders, M; Mundim, L; Murray, W; Muryn, B; Myatt, G; Myklebust, T; Paganoni, M; Nassiakou, M; Paiano, S; Navarria, F; Nawrocki, K; Nicolaidou, R; Nikolenko, M; Ouraou, A; Parkes, C; Oblakowska-Mucha, A; Oyanguren, A; Obraztsov, V F; Olshevskii, A G; Palacios, J P; Onofre, A; Palka, H; Orava, R; Österberg, K; Pape, L; Papadopoulou, T D; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Peralta, L; Perepelitsa, V; Perrotta, A; Petrolini, A; Piedra, J; Pieri, L; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Poireau, V; Pol, M E; Polok, G; Pozdnyakov, V; Pukhaeva, N; Pullia, A; Rames, J; Read, A; Rebecchi, P; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Richard, F; Rídky, J; Rivero, M; Rodríguez, D; Romero, A; Ronchese, P; Roudeau, P; Rovelli, T; Ruhlmann-Kleider, V; Ryabtchikov, D; Sadovskii, A; Salmi, L; Salt, J; Sander, C; Savoy-Navarro, A; Schwickerath, U; Sekulin, R; Siebel, M; Sisakian, A; Smadja, G; Smirnova, O; Sokolov, A; Sopczak, A; Sosnowski, R; Spassoff, Tz; Stanitzki, M; Stocchi, A; Strauss, J; Stugu, B; Szczekowski, M; Szeptycka, M; Szumlak, T; Tabarelli de Fatis, T; Tegenfeldt, F; Timmermans, J; Tkatchev, L G; Tobin, M; Todorovova, S; Tomé, B; Tonazzo, A; Tortosa, P; Travnicek, P; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M L; Tyapkin, I A; Tyapkin, P; Tzamarias, S; Uvarov, V; Valenti, G

    2007-01-01

    Measurements of Zgamma* production are presented using data collected by the DELPHI detector at centre-of-mass energies ranging from 183 to 209 GeV, corresponding to an integrated luminosity of about 667 pb^{-1}. The measurements cover a wide range of the possible final state four-fermion configurations: hadronic and leptonic (e+ e- q qbar, mu+ mu- q qbar, q qbar nu nubar), fully leptonic (l+ l- l'+ l'-) and fully hadronic final states (q qbar q qbar, with a low mass q qbar pair). Measurements of the Zgamma* cross-section for the various final states have been compared with the Standard Model expectations and found to be consistent within the errors. In addition, a total cross-section measurement of the l+ l- l'+ l'- cross-section is reported, and found to be in agreement with the prediction of the Standard Model.

  11. Long term effects of murine postnatal exposure to decabromodiphenyl ether (BDE-209) on learning and memory are dependent upon APOE polymorphism and age

    DEFF Research Database (Denmark)

    Reverte, Ingrid; Klein, Anders Bue; Domingo, José L;

    2014-01-01

    and persistent effects are subject to debate. Of special concern are developmental exposures that can disrupt later-in-life adult health or aging. In this study, we investigated the effects of postnatal exposure to BDE-209 in combination with apolipoprotein E (apoE) genotype, a genetic factor that is associated...

  12. Placental transfer of the polybrominated diphenyl ethers BDE-47, BDE-99 and BDE-209 in a human placenta perfusion system: an experimental study

    DEFF Research Database (Denmark)

    Frederiksen, Marie; Vorkamp, Katrin; Mathiesen, Line;

    2010-01-01

    high concern due to critical windows in fetal development. METHODS: A human ex vivo placenta perfusion system was used to study the kinetics and extent of the placental transfer of BDE-47, BDE-99 and BDE-209 during four-hour perfusions. The PBDEs were added to the maternal circulation and monitored...

  13. DC-SIGN (CD209), pentraxin 3 and vitamin D receptor gene variants associate with pulmonary tuberculosis risk in West Africans

    DEFF Research Database (Denmark)

    Olesen, R; Wejse, C; Velez, D R;

    2007-01-01

    We investigated the role of DC-SIGN (CD209), long pentraxin 3 (PTX3) and vitamin D receptor (VDR) gene single nucleotide polymorphisms (SNPs) in susceptibility to pulmonary tuberculosis (TB) in 321 TB cases and 347 healthy controls from Guinea-Bissau. Five additional, functionally relevant SNPs w...

  14. Interaction at the barrier in the systems 9,10,11Be+209Bi: Well-established facts and open questions

    International Nuclear Information System (INIS)

    The experimental data relative to the interaction for the systems 9,10,11Be+209Bi at the Coulomb barrier are critically discussed and compared also with present theories. The break-up (BU) of the two loosely bound projectiles, 9,11Be, seems to influence the fusion process by ''hindering'' the fusion cross-sections; but, contrary to expectations, the 11Be halo structure has no influence, since no ''enhancement'' is evident from the existing data. Attempt to describe simultaneously all the 9Be+209Bi system data: fusion, elastic scattering and BU, within a coupled-channel (CC) approach is only partly successful. It is important, from a theoretical viewpoint, to include in the CC formalism as well as possible the BU process both to continuum states as well as to unbound resonances. More accurate and well-focused experiments are also necessary to pin down this problem. (orig.)

  15. Calculations of Branching Ratios for Radiative-Capture, One-Proton, and Two-Neutron Channels in the Fusion Reaction $^{209}$Bi+$^{70}$Zn

    CERN Document Server

    Ichikawa, Takatoshi; 10.1143/JPSJ.79.074201

    2010-01-01

    We discuss the possibility of the non-one-neutron emission channels in the cold fusion reaction $^{70}$Zn + $^{209}$Bi to produce the element Z=113. For this purpose, we calculate the evaporation-residue cross sections of one-proton, radiative-capture, and two-neutron emissions relative to the one-neutron emission in the reaction $^{70}$Zn + $^{209}$Bi. To estimate the upper bounds of those quantities, we vary model parameters in the calculations, such as the level-density parameter and the height of the fission barrier. We conclude that the highest possibility is for the 2n reaction channel, and its upper bounds are 2.4$%$ and at most less than 7.9% with unrealistic parameter values, under the actual experimental conditions of [J. Phys. Soc. Jpn. {\\bf 73} (2004) 2593].

  16. Neuromodulatory role of Bacopa monnieri on oxidative stress induced by postnatal exposure to decabromodiphenyl ether (PBDE -209 in neonate and young female mice

    Directory of Open Access Journals (Sweden)

    Priya Verma

    2014-04-01

    Full Text Available Objective(s:Bacopa monnieri (BM,a traditional ayurvedic medicine,is a well-known memory enhancer. We have explored the role of BM against decabrominated diphenyl ether (PBDE-209-induced alterations in neonate and young female mice. Materials and Methods: Mice were orally administered with B. monnieri at the doses of 40, 80 or 120 mg/kg body weight along with PBDE-209 (20 mg/kg body weight from postnatal day (PND 3-10. Levels of malondialdehyde, protein carbonyl and activities of superoxide dismutase and glutathione peroxidase were measured at both ages. The correct choices and reference/working memory errors of young mice were evaluated by Morris water and radial arm maze. Results: The results showed that BM at the dose of 120 mg/kg significantly (P

  17. Investigations of the potential for accident mitigation of the conceptical design for a core retention device developed in SR 209

    International Nuclear Information System (INIS)

    The potential for accident mitigation of the conceptual design for the core retention device developed in SR 209, was estimated by core meltdown and containment analyses. Such a device should prevent late fission product release especially due to failure of the containment by overpressurization (according to release categories 5 and 6 of the German Risk Study, Phase A). Assuming ideal operation of the device, the long term course of a meltdown accident can be influenced in a positive sense including the prevention of overpressurization. However, functional operation of the design seems to be highly uncertain for several reasons, i.g. due to uncertainties in the behaviour of the melt in the retention device. The design does not or only insufficiently cover accident scenarios with high pressure in vessel melt, that means for sequences relevant for their high contribution to core melt frequency. The design may have strong negative impacts on the course of meltdown accidents, LOCA's, constructive details and operation of a plant. Implementation of the measure is expected to need extreme effort, without making sense from the technical point of view. The measure at all seems not to be recommendable for accident mitigation. (orig./HP)

  18. Colour reconnection in $e^{+}e^{-} \\rightarrow W^{+}W^{-}$ at $\\sqrt{s}=189-209 GeV$

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Asai, S; Axen, D A; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brown, R M; Burckhart, H J; Campana, S; Capiluppi, P; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, R J; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanzaki, J; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krieger, P; Von, J H; Krogh, A; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Mashimo, T; Mättig, P; McKenna, J A; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rossi, A M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2006-01-01

    The effects of the final state interaction phenomenon known as colour reconnection are investigated at centre-of-mass energies in the range $\\sqrt{s}~ 189-209 GeV using the OPAL detector at LEP. Colour reconnection is expected to affect observables based on charged particles in hadronic decays of W+W-. Measurements of inclusive charged particle multiplicities, and of their angular distribution with respect to the four jet axes of the events, are used to test models of colour reconnection. The data are found to exclude extreme scenarios of the Sjostrand-Khoze Type I (SK-I) model and are compatible with other models, both with and without colour reconnection effects. In the context of the SK-I model, the best agreement with data is obtained for a reconnection probability of 37%. Assuming no colour reconnection, the charged particle multiplicity in hadronically decaying W bosons is measured to be (nqqch) = 19.38+-0.05(stat.)+-0.08 (syst.).

  19. Study of the di-nuclear system $^{A}$Rb + $^{209}$Bi (Z$_{1}$ + Z$_{2}$ = 120)

    CERN Multimedia

    The exact location of the next spherical shell closures beyond Z = 82, N = 126 is still an open question. According to model predictions shell closures are expected at Z = 114 or 120 or 126 and N = 184. Also experimental data cannot yet give a definite answer. Known nuclei with Z = 114 are too neutron‐deficient with respect to the N = 184 shell and nuclei with Z = 120 and beyond are still unknown. An option for studying reactions of super-heavy systems at Z = 120 and neutron numbers up to 184 becomes possible with the use of $^{209}$Bi targets and neutron‐rich beams. By studying quasi-fission and fusion‐fission reactions, which have significantly larger production cross‐sections than the evaporation residues, a possible influence of shell closures at Z = 120, N = 184 can be explored. Well suitable for such studies will be neutron‐rich rubidium beams at energies of about 5 MeV/u delivered by the HIE‐ISOLDE facility.

  20. Fission cross section calculations for 209Bi target nucleus based on fission reaction models in high energy regions

    Directory of Open Access Journals (Sweden)

    Kaplan Abdullah

    2015-01-01

    Full Text Available Implementation of projects of new generation nuclear power plants requires the solving of material science and technological issues in developing of reactor materials. Melts of heavy metals (Pb, Bi and Pb-Bi due to their nuclear and thermophysical properties, are the candidate coolants for fast reactors and accelerator-driven systems (ADS. In this study, α, γ, p, n and 3He induced fission cross section calculations for 209Bi target nucleus at high-energy regions for (α,f, (γ,f, (p,f, (n,f and (3He,f reactions have been investigated using different fission reaction models. Mamdouh Table, Sierk, Rotating Liquid Drop and Fission Path models of theoretical fission barriers of TALYS 1.6 code have been used for the fission cross section calculations. The calculated results have been compared with the experimental data taken from the EXFOR database. TALYS 1.6 Sierk model calculations exhibit generally good agreement with the experimental measurements for all reactions used in this study.

  1. Thick target yield measurement of {sup 211}At through the nuclear reaction {sup 209}Bi({alpha}, 2n)

    Energy Technology Data Exchange (ETDEWEB)

    Alfarano, A [Institute for Health and Consumer Protection, IHCP, Joint Research Centre, via E. Fermi 1, 21020 Ispra, Varese (Italy); Abbas, K [Institute for Health and Consumer Protection, IHCP, Joint Research Centre, via E. Fermi 1, 21020 Ispra, Varese (Italy); Holzwarth, U [Institute for Health and Consumer Protection, IHCP, Joint Research Centre, via E. Fermi 1, 21020 Ispra, Varese (Italy); Bonardi, M [Universita degli Studi di Milano and INFN-Milano, LASA, Radiochemistry Laboratory, via F.lli Cervi 201, 20090 Segrate, Milan (Italy); Groppi, F [Universita degli Studi di Milano and INFN-Milano, LASA, Radiochemistry Laboratory, via F.lli Cervi 201, 20090 Segrate, Milan (Italy); Alfassi, Z [Department of Nuclear Engineering, Ben Gurion University, 84105 Beer Sheva (Israel); Menapace, E [ENEA, Applied Physics Division, Bologna (Italy); Gibson, P N [Institute for Health and Consumer Protection, IHCP, Joint Research Centre, via E. Fermi 1, 21020 Ispra, Varese (Italy)

    2006-05-15

    Radionuclide Therapy (RNT) and Radioimmunotherapy (RIT) are potentially of great interest for cancer therapy. In many therapeutic applications alpha emitters should be much more effective than already-approved beta emitters due to the short range and high linear energy transfer of alpha particles. {sup 213}Bi is an important alpha emitter already used in clinical trials but the half-life of this radioisotope is short (46 minutes) and so its use is limited for certain therapies. {sup 211}At is potentially very interesting for medical purposes because of its longer half-life of 7.2 hours, and suitable decay scheme. We have studied the cyclotron-based production of {sup 211}At via the reaction {sup 209}Bi({alpha}, 2n), this production route probably being the most promising in the long term. The energy dependence of thick target yields and the reaction cross sections for the production of {sup 211}At and {sup 210}At were determined and found to be in good agreement with literature. The best energy to produce {sup 211}At is 28-29 MeV. The possible production of the undesired, highly radiotoxic, and long-lived alpha-emitting {sup 210}Po (138.38 days), which is produced from decay of {sup 210}At, is also discussed.

  2. Search for Charged Higgs Bosos in $e^{+}e^{-}$ Collisions at $\\sqrt{s}$ = 189-209 GeV

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Anagnostou, G; Anderson, K J; Asai, S; Axen, D; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, R J; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, S; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brown, R M; Burckhart, H J; Campana, S; Capiluppi, P; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; Dallavalle, M; de Roeck, A; De Wolf, E A; Desch, K; Dienes, B; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, F; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, J; Gruwé, M; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Herten, G; Heuer, R D; Hill, J C; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanzaki, J; Karlen, D; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krasznahorkays, A Jr; Krieger, P; Von Krogh, J; Kühl, T; Kupper, M; Lafferty, G D; Landsman, H; Lanske, D; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Mashimo, T; Mättig, P; McKenna, J; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, V; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Pooth, O; Przybycien, M; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rossi, A M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schiecks, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, J; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2012-01-01

    A search is made for charged Higgs bosons predicted by Two-Higgs-Doublet extensions of the Standard Model (2HDM) using electron-positron collision data collected by the OPAL experiment at sqrts=189-209 GeV, corresponding to an integrated luminosity of approximately 600pb-1. Charged Higgs bosons are assumed to be pair-produced and to decay into qq, tnt or AWpm. No signal is observed. Model-independent limits on the charged Higgs-boson production cross section are derived by combining these results with previous searches at lower energies. Excluded areas on the [mHpm, BR(Hpm->TV)] plane are presented assuming BR(Hpm->tnt)+BR(Hpm->qq)=1. Under the above assumption, motivated by general 2HDM type II models, charged Higgs bosons are excluded up to a mass of 76.6GeV at 95% confidence level, independent of the branching ratio BR(Hpm->tnt). A scan of the 2HDM type I model parameter space is performed and limits on the Higgs-boson masses mHpm and mA are presented for different choices of tanb.

  3. Search for Chargino and Neutralino Production at $\\sqrt{s}$ = 192-209 GeV at LEP

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Arcelli, S; Asai, S; Axen, D A; Azuelos, Georges; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brigliadori, L; Brown, R M; Büsser, K; Burckhart, H J; Campana, S; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, Akos; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Feld, L; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Gaycken, G; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, Richard J; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanaya, N; Kanzaki, J; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, Richard K; Kellogg, R G; Kennedy, B W; Klein, K; Klier, A; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krieger, P; Von Krogh, J; Krüger, K; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Layter, J G; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Marchant, T E; Mashimo, T; Mättig, P; McKenna, J A; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Michelini, Aldo; Mihara, S; Mikenberg, G; Miller, D J; Moed, S; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Okpara, A N; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Poli, B; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rosati, S; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Scott, W G; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Waller, D; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wetterling, D; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2004-01-01

    Approximately 438 pb-1 of e+e- data from the OPAL detector, taken with the LEP collider running at centre-of-mass energies of 192-209 Gev, are analyzed to search for evidence of chargino pair production, e+e- -> tilde chi^+_1 tilde chi^-_1, or neutralino associated production, e+e- -> tilde chi^0_2 tilde chi^0_1. Limits are set at the 95% confidence level on the product of the cross-section for the process e+e- -> tilde chi^+_1 tilde chi^-_1 and its branching ratios to topologies containing jets and missing energy, of jest with a lepton and missing energy, and on the product of the cross-section for e+e- -> tilde chi^0_2 tilde chi^0_1 and its branching ratio to jets. R-parity conservation is assumed throughout this paper. When these results are interpreted in the context of the Constrained Minimal Supersymmetric Standard Model, limits are also set on the masses of the tilde chi^+-_1, tilde chi^0_1 and tilde chi^0_2, and regions of the parameter space of the model are ruled out. Nearly model-independent limits...

  4. Exploring contributions from incomplete fusion in $^{6,7}$Li+$^{209}$Bi and $^{6,7}$Li+$^{198}$Pt reactions

    CERN Document Server

    Parkar, V V; Kailas, S

    2016-01-01

    We use the breakup absorption model to simultaneously describe the measured cross-sections of the Complete fusion (CF), Incomplete fusion (ICF), and Total fusion (TF) in nuclear reactions induced by weakly bound nuclei $^{6,7}$Li on $^{209}$Bi and $^{198}$Pt targets. The absorption cross-sections are calculated using the Continuum Discretized Coupled Channels (CDCC) method with different choices of short range imaginary potentials to get the ICF, CF and TF cross-sections. It is observed that the cross-sections for deuteron-ICF/deuteron-capture are of similar magnitude as the $\\alpha$-ICF/$\\alpha$-capture, in case of $^{6}$Li projectile, while the cross-sections for triton-ICF/triton-capture is more dominant than $\\alpha$-ICF/$\\alpha$-capture in case of $^{7}$Li projectile. Both these observations are also corroborated by the experimental data. The ratio of ICF to TF cross-sections, which defines the value of fusion suppression factor is found to be in agreement with the data available from the literature. The...

  5. Exploring contributions from incomplete fusion in Li,76+209Bi and Li,76+198Pt reactions

    Science.gov (United States)

    Parkar, V. V.; Jha, V.; Kailas, S.

    2016-08-01

    We use the breakup absorption model to simultaneously describe the measured cross sections of complete fusion (CF), incomplete fusion (ICF), and total fusion (TF) in nuclear reactions induced by weakly bound nuclei Li,76 on 209Bi and 198Pt targets. The absorption cross sections are calculated using the continuum discretized coupled channels (CDCC) method with different choices of short-range imaginary potentials to get the ICF, CF, and TF cross sections. It is observed that the cross sections for deuteron ICF / deuteron capture and α ICF / α capture are of similar magnitude, in the case of the 6Li projectile, while the cross sections for the triton ICF / triton capture is more dominant than that of α ICF / α capture in the case of the 7Li projectile. Both these observations are also corroborated by the experimental data. The ratio of ICF to TF cross sections, which defines the value of fusion suppression factor, is found to be in agreement with the data available from the literature. The cross-section ratios of CF/TF and ICF/TF show opposite behavior at below-barrier energies the former decreases while the latter increases as the energy is lowered, which shows the dominance of ICF at below-barrier energies. We have also studied the correlation of the ICF cross sections with the noncapture breakup (NCBU) cross sections as a function of energy, which shows that the NCBU is more significant than ICF at below-barrier energies.

  6. Measurement of the W-pair Production Cross-section and W Branching Ratios in $e^+ e^-$ Collisions at $\\sqrt{s}$ = 161-209 GeV

    CERN Document Server

    Abdallah, J; Adam, W; Adzic, P; Albrecht, T; Alderweireld, T; Alemany-Fernandez, R; Allmendinger, T; Allport, P P; Amaldi, Ugo; Amapane, N; Amato, S; Anashkin, E; Andreazza, A; Andringa, S; Anjos, N; Antilogus, P; Apel, W D; Arnoud, Y; Ask, S; Åsman, B; Augustin, J E; Augustinus, A; Baillon, Paul; Ballestrero, A; Bambade, P; Barbier, R; Bardin, Dimitri Yuri; Barker, G; Baroncelli, A; Battaglia, Marco; Baubillier, M; Becks, K H; Begalli, M; Behrmann, A; Ben-Haim, E; Benekos, N C; Benvenuti, Alberto C; Bérat, C; Berggren, M; Berntzon, L; Bertrand, D; Besançon, M; Besson, N; Bloch, D; Blom, M; Bluj, M; Bonesini, M; Boonekamp, M; Booth, P S L; Borisov, G; Botner, O; Bouquet, B; Bowcock, T J V; Boyko, I; Bracko, M; Brenner, R; Brodet, E; Brückman, P; Brunet, J M; Bugge, L; Buschmann, P; Calvi, M; Camporesi, T; Canale, V; Carena, F; Castro, N; Cavallo, F R; Chapkin, M M; Charpentier, P; Checchia, P; Chierici, R; Shlyapnikov, P; Chudoba, J; Chung, S U; Cieslik, K; Collins, P; Contri, R; Cosme, G; Cossutti, F; Costa, M J; Crennell, D J; Cuevas-Maestro, J; D'Hondt, J; Dalmau, J; Da Silva, T; Da Silva, W; Della Ricca, G; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Maria, N; De Min, A; De Paula, L S; Di Ciaccio, Lucia; Di Simone, A; Doroba, K; Drees, J; Dris, M; Eigen, G; Ekelöf, T J C; Ellert, M; Elsing, M; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Feindt, M; Fernández, J; Ferrer, A; Ferro, F; Flagmeyer, U; Föth, H; Fokitis, E; Fulda-Quenzer, F; Fuster, J A; Gandelman, M; García, C; Gavillet, P; Gazis, E N; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; Graziani, E; Grosdidier, G; Grzelak, K; Guy, J; Haag, C; Hallgren, A; Hamacher, K; Hamilton, K; Haug, S; Hauler, F; Hedberg, V; Hennecke, M; Herr, H; Hoffman, J; Holmgren, S O; Holt, P J; Houlden, M A; Hultqvist, K; Jackson, J N; Jarlskog, G; Jarry, P; Jeans, D; Johansson, E K; Johansson, P D; Jonsson, P; Joram, C; Jungermann, L; Kapusta, F; Katsanevas, S; Katsoufis, E C; Kernel, G; Kersevan, Borut P; Kerzel, U; Kiiskinen, A P; King, B T; Kjaer, N J; Kluit, P; Kokkinias, P; Kourkoumelis, C; Kuznetsov, O; Krumshtein, Z; Kucharczyk, M; Lamsa, J; Leder, G; Ledroit, F; Leinonen, L; Leitner, R; Lemonne, J; Lepeltier, V; Lesiak, T; Liebig, W; Liko, D; Lipniacka, A; Lopes, J H; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Malek, A; Maltezos, S; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Masik, J; Mastroyiannopoulos, N; Matorras, F; Matteuzzi, C; Mazzucato, F; Mazzucato, M; McNulty, R; Meroni, C; Migliore, E; Mitaroff, W A; Mjörnmark, U; Moa, T; Moch, M; Mönig, K; Monge, R; Montenegro, J; Moraes, D; Moreno, S; Morettini, P; Müller, U; Münich, K; Mulders, M; Mundim, L M; Murray, W; Muryn, B; Myatt, Gerald; Myklebust, T; Nassiakou, M; Navarria, Francesco Luigi; Nawrocki, K; Nicolaidou, R; Nikolenko, M; Oblakowska-Mucha, A; Obraztsov, V F; Olshevskii, A G; Onofre, A; Orava, Risto; Österberg, K; Ouraou, A; Oyanguren, A; Paganoni, M; Paiano, S; Palacios, J P; Palka, H; Papadopoulou, T D; Pape, L; Parkes, C; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Peralta, L; Perepelitsa, V F; Perrotta, A; Petrolini, A; Piedra, J; Pieri, L; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Poireau, V; Pol, M E; Polok, G; Poropat, P; Pozdnyakov, V; Pukhaeva, N; Pullia, Antonio; Rames, J; Ramler, L; Read, A; Rebecchi, P; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Richard, F; Rídky, J; Rivero, M; Rodríguez, D; Romero, A; Ronchese, P; Roudeau, Patrick; Rovelli, T; Ruhlmann-Kleider, V; Ryabtchikov, D; Sadovskii, A; Salmi, L; Salt, J; Savoy-Navarro, A; Schwickerath, U; Segar, A; Sekulin, R L; Siebel, M; Sissakian, A N; Smadja, G; Smirnova, O G; Sokolov, A; Sopczak, A; Sosnowski, R; Spassoff, Tz; Stanitzki, M; Stocchi, A; Strauss, J; Stugu, B; Szczekowski, M; Szeptycka, M; Szumlak, T; Tabarelli de Fatis, T; Taffard, A C; Tegenfeldt, F; Timmermans, J; Tkatchev, L G; Tobin, M; Todorovova, S; Tomé, B; Tonazzo, A; Tortosa, P; Travnicek, P; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M L; Tyapkin, I A; Tyapkin, P; Tzamarias, S; Uvarov, V; Valenti, G; van Dam, P; Van Eldik, J; Van Lysebetten, A; Van Remortel, N; Van Vulpen, I B; Vegni, G; Veloso, F; Venus, W A; Verdier, P; Verzi, V; Vilanova, D; Vitale, L; Vrba, V; Wahlen, H; Washbrook, A J; Weiser, C; Wicke, D; Wickens, J H; Wilkinson, G; Winter, M; Witek, M; Yushchenko, O P; Zalewska-Bak, A; Zalewski, Piotr; Zavrtanik, D; Zhuravlov, V; Zimin, N I; Zinchenko, A I; Zupan, M

    2004-01-01

    These final results on e+e- -> W+W- production cross-section measurements at LEP2 use data collected by the DELPHI detector at centre-of-mass energies up to 209 GeV. Measurements of total cross-sections, W angular differential distributions and decay branching fractions, and the value of the CKM element |V_{cs}| are compared to the expectations of the Standard Model. These results supersede all values previously published by DELPHI.

  7. Oceanographic profile data collected aboard NAVIGATION RESPONSE TEAM 7 as part of project S-G905-NRT2-09 in the North Atlantic Ocean from 2009-11-17 to 2010-03-23 (NCEI Accession 0130673)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — NCEI Accession 0130673 includes physical and profile data collected aboard the NAVIGATION RESPONSE TEAM 7 during project S-G905-NRT2-09 in the North Atlantic Ocean...

  8. Meteor showers from comet 209P/Linear at Earth and comet C/2013 A1 (Siding Spring) at Mars

    Science.gov (United States)

    Jenniskens, P. M. M.

    2014-12-01

    The exceptionally close encounter of long-period comet comet C/2013 A1 (Siding Spring) to Mars on October 19, 2014, may result in the first meteor observations in the atmosphere of Mars. Large (few-mm to cm-sized) meteoroids are not easily observed by other techniques. The manner in which these meteoroids fragment will shed light on the physical properties of large freshly-ejected dust grains of a long-period comet, which carry most of the comet's mass loss. Their physical properties may be very different than those of the much more aged meteoroids typically encountered in annual meteor showers and the sporadic meteor background. The 2014 May 24 close encounter of comet 209P/LINEAR to Earth, for example, showed that the meteoroids ejected by this short-period comet about 100 years ago were still unusually fragile, some breaking vigorously into a cloud of dust towards the end of their entry trajectories. Moreover, the meteoroid stream encountered by Earth was dominated by small meteoroids, with a steep differential mass distribution index of s = 2.42+/-0.15 (0.003-4 g) and a differential size distribution index of a = 5.3 +/- 0.4 (0.2-2 cm). The fragile nature of the grains is likely the reason for the lack of large meteoroids in the stream. The encounter with comet Siding Spring may shed light onto the question whether this is because they do not survive the ejection process (in which case the shower on Mars would also lack bright meteors) or because they do not survive the thermal cycling in interplanetary space for more than a century or so (in which case larger meteoroids may still be present in the stream).

  9. Placental transfer of the polybrominated diphenyl ethers BDE-47, BDE-99 and BDE-209 in a human placenta perfusion system: an experimental study

    Directory of Open Access Journals (Sweden)

    Frederiksen Marie

    2010-07-01

    Full Text Available Abstract Background Polybrominated diphenyl ethers (PBDEs have been widely used as flame retardants in consumer products. PBDEs may affect thyroid hormone homeostasis, which can result in irreversible damage of cognitive performance, motor skills and altered behaviour. Thus, in utero exposure is of very high concern due to critical windows in fetal development. Methods A human ex vivo placenta perfusion system was used to study the kinetics and extent of the placental transfer of BDE-47, BDE-99 and BDE-209 during four-hour perfusions. The PBDEs were added to the maternal circulation and monitored in the maternal and fetal compartments. In addition, the perfused cotyledon, the surrounding placental tissue as well as pre-perfusion placental tissue and umbilical cord plasma were also analysed. The PBDE analysis included Soxhlet extraction, clean-up by adsorption chromatography and GC-MS analysis. Results and Discussion Placental transfer of BDE-47 was faster and more extensive than for BDE-99. The fetal-maternal ratios (FM-ratio after four hours of perfusion were 0.47 and 0.25 for BDE-47 and BDE-99, respectively, while the indicative permeability coefficient (IPC measured after 60 minutes of perfusion was 0.26 h-1 and 0.10 h-1, respectively. The transport of BDE-209 seemed to be limited. These differences between the congeners may be related to the degree of bromination. Significant accumulation was observed for all congeners in the perfused cotyledon as well as in the surrounding placental tissue. Conclusion The transport of BDE-47 and BDE-99 indicates in utero exposure to these congeners. Although the transport of BDE-209 was limited, however, possible metabolic debromination may lead to products which are both more toxic and transportable. Our study demonstrates fetal exposure to PBDEs, which should be included in risk assessment of PBDE exposure of women of child-bearing age.

  10. A flavour-independent Higgs boson search in $e^+ e^-$ collisions at $\\sqrt{s}$ up to 209 GeV

    CERN Document Server

    Heister, A; Barate, R; Brunelière, R; De Bonis, I; Décamp, D; Goy, C; Jézéquel, S; Lees, J P; Martin, F; Merle, E; Minard, M N; Pietrzyk, B; Trocmé, B; Boix, G; Bravo, S; Casado, M P; Chmeissani, M; Crespo, J M; Fernández, E; Fernández-Bosman, M; Garrido, L; Graugès-Pous, E; López, J; Martínez, M; Merino, G; Miquel, R; Mir, L M; Pacheco, A; Paneque, D; Ruiz, H; Colaleo, A; Creanza, D; De Filippis, N; De Palma, M; Iaselli, Giuseppe; Maggi, G; Maggi, M; Nuzzo, S; Ranieri, A; Raso, G; Ruggieri, F; Selvaggi, G; Silvestris, L; Tempesta, P; Tricomi, A; Zito, G; Huang, X; Lin, J; Ouyang, Q; Wang, T; Xie, Y; Xu, R; Xue, S; Zhang, J; Zhang, L; Zhao, W; Abbaneo, D; Azzurri, P; Barklow, Timothy L; Buchmüller, O L; Cattaneo, M; Cerutti, F; Clerbaux, B; Drevermann, H; Forty, Roger W; Frank, M; Gianotti, F; Greening, T C; Hansen, J B; Harvey, J; Hutchcroft, D E; Janot, P; Jost, B; Kado, M; Mato, P; Moutoussi, A; Ranjard, F; Rolandi, Luigi; Schlatter, W D; Sguazzoni, G; Tejessy, W; Teubert, F; Valassi, Andrea; Videau, I; Ward, J J; Badaud, F; Dessagne, S; Falvard, A; Fayolle, D; Gay, P; Jousset, J; Michel, B; Monteil, S; Pallin, D; Pascolo, J M; Perret, P; Hansen, J D; Hansen, J R; Hansen, P H; Nilsson, B S; Kyriakis, A; Markou, C; Simopoulou, Errietta; Vayaki, Anna; Zachariadou, K; Blondel, A; Brient, J C; Machefert, F P; Rougé, A; Swynghedauw, M; Tanaka, R; Videau, H L; Ciulli, V; Focardi, E; Parrini, G; Antonelli, A; Antonelli, M; Bencivenni, G; Bossi, F; Capon, G; Chiarella, V; Laurelli, P; Mannocchi, G; Murtas, G P; Passalacqua, L; Kennedy, J; Lynch, J G; Negus, P; O'Shea, V; Thompson, A S; Wasserbaech, S R; Cavanaugh, R J; Dhamotharan, S; Geweniger, C; Hanke, P; Hepp, V; Kluge, E E; Leibenguth, G; Putzer, A; Stenzel, H; Tittel, K; Wunsch, M; Beuselinck, R; Cameron, W; Davies, G; Dornan, Peter J; Girone, M; Hill, R D; Marinelli, N; Nowell, J; Rutherford, S A; Sedgbeer, J K; Thompson, J C; White, R; Ghete, V M; Girtler, P; Kneringer, E; Kuhn, D; Rudolph, G; Bouhova-Thacker, E; Bowdery, C K; Clarke, D P; Ellis, G; Finch, A J; Foster, F; Hughes, G; Jones, R W L; Pearson, M R; Robertson, N A; Smizanska, M; van der Aa, O; Delaere, C; Lemaître, V; Blumenschein, U; Hölldorfer, F; Jakobs, K; Kayser, F J; Kleinknecht, K; Müller, A S; Quast, G; Renk, B; Sander, H G; Schmeling, S; Wachsmuth, H W; Zeitnitz, C; Ziegler, T; Bonissent, A; Coyle, P; Curtil, C; Ealet, A; Fouchez, D; Payre, P; Tilquin, A; Ragusa, F; David, A; Dietl, H; Ganis, G; Hüttmann, K; Lütjens, G; Männer, W; Moser, H G; Settles, Ronald; Wolf, G; Boucrot, J; Callot, O; Davier, M; Duflot, L; Grivaz, J F; Heusse, P; Jacholkowska, A; Loomis, C; Serin, L; Veillet, J J; De Vivie de Régie, J B; Yuan, C; Bagliesi, G; Boccali, T; Foà, L; Giammanco, A; Giassi, A; Ligabue, F; Messineo, A; Palla, Fabrizio; Sanguinetti, G; Sciabà, A; Tenchini, Roberto; Venturi, A; Verdini, P G; Awunor, O; Blair, G A; Cowan, G; García-Bellido, A; Green, M G; Jones, L T; Medcalf, T; Misiejuk, A; Strong, J A; Teixeira-Dias, P; Clifft, R W; Edgecock, T R; Norton, P R; Tomalin, I R; Bloch-Devaux, B; Boumediene, D E; Colas, P; Fabbro, B; Lançon, E; Lemaire, M C; Locci, E; Pérez, P; Rander, J; Tuchming, B; Vallage, B; Konstantinidis, N P; Litke, A M; Taylor, G; Booth, C N; Cartwright, S L; Combley, F; Hodgson, P N; Lehto, M H; Thompson, L F; Affholderbach, K; Böhrer, A; Brandt, S; Grupen, Claus; Hess, J; Ngac, A; Prange, G; Sieler, U; Borean, C; Giannini, G; He, H; Pütz, J; Rothberg, J E; Armstrong, S R; Berkelman, K; Cranmer, K; Ferguson, D P S; Gao, Y; González, S; Hayes, O J; Hu, H; Jin, S; Kile, J; McNamara, P A; Nielsen, J; Pan, Y B; Von Wimmersperg-Töller, J H; Wiedenmann, W; Wu, J; Wu Sau Lan; Wu, X; Zobernig, G; Dissertori, G

    2002-01-01

    A search for the Higgsstrahlung process e+e- -> HZ is carried out, covering decays of the Higgs boson into any quark pair, a gluon pair or a tau pair. The analysis is based on the 630pb-1 of data collected by the ALEPH detector at LEP at centre-of-mass energies from 189 to 209GeV. A 95% C.L. lower mass limit of 109.1GeV/c2 is obtained for a Higgs boson cross section equal to that expected from the Standard Model if the Higgs boson decays exclusively into hadrons and/or taus, irrespective of the relative branching fractions.

  11. Studies of Hadronic Event Structure in $e^+ e^-$ Annihilation from 30 GeV to 209 GeV with the L3 Detector

    CERN Document Server

    Achard, P; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Anderhub, H; Andreev, V P; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, G; Baksay, L; Baldew, S V; Banerjee, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Biasini, M; Biglietti, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bottai, S; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Chamizo-Llatas, M; Chang, Y H; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; de la Cruz, B; Cucciarelli, S; van Dalen, J A; De Asmundis, R; Déglon, P L; Debreczeni, J; Degré, A; Dehmelt, K; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Dionisi, C; Dittmar, M; Doria, A; Dova, M T; Duchesneau, D; Duda, M; Echenard, B; Eline, A; El-Hage, A; El-Mamouni, H; Engler, A; Eppling, F J; Extermann, P; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, M; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, F; Fisher, P H; Fisher, W; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gentile, S; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hirschfelder, J; Hofer, H; Hohlmann, M; Holzner, G; Hou, S R; Hu, Y; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Kaur, M; Kienzle-Focacci, M N; Kim, J K; Kirkby, Jasper; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Koutsenko, V F; Kräber, M H; Krämer, R W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Levtchenko, M; Levchenko, P M; Li, C; Likhoded, S; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Luci, C; Luminari, L; Lustermann, W; Ma Wen Gan; Malgeri, L; Malinin, A; Maña, C; Mans, J; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Nagy, S; Natale, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Nisati, A; Novák, T; Nowak, H; Ofierzynski, R A; Organtini, G; Pal, I; Palomares, C; Paolucci, P; Paramatti, R; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pioppi, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Pothier, J; Prokofev, D; Prokofiev, D O; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Roe, B P; Romero, L; Rosca, A; Rosemann, C; Rosenbleck, C; Rosier-Lees, S; Roth, S; Rubio, J A; Ruggiero, G; Rykaczewski, H; Sakharov, A; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Schäfer, C; Shchegelskii, V; Schopper, Herwig Franz; Schotanus, D J; Sciacca, C; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Son, D; Souga, C; Spillantini, P; Steuer, M; Stickland, D P; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S; Suter, H; Swain, J D; Szillási, Z; Tang, X W; Tarjan, P; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Ulbricht, J; Valente, E; Van de Walle, R T; Vásquez, R; Veszpremi, V; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Wadhwa, M; Wang, Q; Wang, X L; Wang, Z M; Weber, M; Wilkens, H; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhao, J; Zhu, G Y; Zhu, R Y; Zhuang, H L; Zichichi, A; Zimmermann, B; Zöller, M

    2004-01-01

    In this Report, QCD results obtained from a study of hadronic event structure in high energy e^+e^- interactions with the L3 detector are presented. The operation of the LEP collider at many different collision energies from 91 GeV to 209 GeV offers a unique opportunity to test QCD by measuring the energy dependence of different observables. The main results concern the measurement of the strong coupling constant, \\alpha_s, from hadronic event shapes and the study of effects of soft gluon coherence through charged particle multiplicity and momentum distributions.

  12. Isotope Shifts of the $6d\\,^2$D$_{3/2}\\,$ - $7p\\,^2$P$_{1/2}\\,$ Transition in Trapped Short-Lived $^{209-214}$Ra$^+$

    CERN Document Server

    Giri, G S; Berg, J E van den; Böll, O; Dammalapati, U; van der Hoek, D J; Jungmann, K; Kruithof, W L; Müller, S; Portela, M Nuñez; Onderwater, C J G; Santra, B; Timmermans, R G E; Wansbeek, L W; Willmann, L; Wilschut, H W

    2011-01-01

    Laser spectroscopy of short-lived radium isotopes in a linear Paul trap has been performed. The isotope shifts of the $6d\\,^2$D$_{3/2}\\,$ - $7p\\,^2$P$_{1/2}\\,$ transition in $^{209-214}$Ra$^+$ were measured, which are sensitive to the short range part of the atomic wavefunctions. The results are essential experimental input for improving the precision of atomic structure calculation. This is indispensable for parity violation in Ra$^+$ aiming at the determination of the weak mixing angle.

  13. Measurement of the photon-proton total cross section at a center-of-mass energy of 209 GeV at HERA

    International Nuclear Information System (INIS)

    The photon-proton total cross section has been measured in the process e+p→e+γp→e+X with the ZEUS detector at HERA. Events were collected with photon virtuality Q22 and average γp center-of-mass energy Wγp=209 GeV in a dedicated run, designed to control systematic effects, with an integrated luminosity of 49 nb-1. The measured total cross section is σtotγp=174±1 (stat.)±13 (syst.) μb. The energy dependence of the cross section is compatible with parameterizations of high-energy pp and pp-bar data

  14. DUST FROM COMET 209P/LINEAR DURING ITS 2014 RETURN: PARENT BODY OF A NEW METEOR SHOWER, THE MAY CAMELOPARDALIDS

    International Nuclear Information System (INIS)

    We report a new observation of the Jupiter family comet 209P/LINEAR during its 2014 return. The comet is recognized as a dust source of a new meteor shower, the May Camelopardalids. 209P/LINEAR was apparently inactive at a heliocentric distance rh = 1.6 AU and showed weak activity at rh ≤ 1.4 AU. We found an active region of <0.001% of the entire nuclear surface during the comet's dormant phase. An edge-on image suggests that particles up to 1 cm in size (with an uncertainty of factor 3-5) were ejected following a differential power-law size distribution with index q = –3.25 ± 0.10. We derived a mass-loss rate of 2-10 kg s–1 during the active phase and a total mass of ≈5 × 107 kg during the 2014 return. The ejection terminal velocity of millimeter- to centimeter-sized particles was 1-4 m s–1, which is comparable to the escape velocity from the nucleus (1.4 m s–1). These results imply that such large meteoric particles marginally escaped from the highly dormant comet nucleus via the gas drag force only within a few months of the perihelion passage

  15. DUST FROM COMET 209P/LINEAR DURING ITS 2014 RETURN: PARENT BODY OF A NEW METEOR SHOWER, THE MAY CAMELOPARDALIDS

    Energy Technology Data Exchange (ETDEWEB)

    Ishiguro, Masateru [Department of Physics and Astronomy, Seoul National University, Gwanak, Seoul 151-742 (Korea, Republic of); Kuroda, Daisuke [Okayama Astrophysical Observatory, National Astronomical Observatory of Japan, Asakuchi, Okayama 719-0232 (Japan); Hanayama, Hidekazu [Ishigakijima Astronomical Observatory, National Astronomical Observatory of Japan, Ishigaki, Okinawa 907-0024 (Japan); Takahashi, Jun; Takagi, Yuhei; Morihana, Kumiko; Honda, Satoshi; Arai, Akira [Nishi-Harima Astronomical Observatory, Center for Astronomy, University of Hyogo, Sayo, Hyogo 679-5313 (Japan); Hasegawa, Sunao; Sarugaku, Yuki [Institute of Space and Astronautical Science (ISAS), Japan Aerospace Exploration Agency (JAXA), Sagamihara, Kanagawa 252-5210 (Japan); Watanabe, Makoto; Imai, Masataka; Goda, Shuhei [Department of Cosmosciences, Graduate School of Science, Hokkaido University, Sapporo 060-0810 (Japan); Akitaya, Hiroshi [Hiroshima Astrophysical Science Center, Hiroshima University, Higashihiroshima, Hiroshima 739-8526 (Japan); Sekiguchi, Kazuhiro [National Astronomical Observatory of Japan, National Institute of Natural Sciences, Mitaka, Tokyo 181-8588 (Japan); Oasa, Yumiko [Faculty of Education, Saitama University, Sakura, Saitama 338-8570 (Japan); Saito, Yoshihiko [Department of Physics, Tokyo Institute of Technology, Meguro-ku, Tokyo 152-8551 (Japan); Morokuma, Tomoki [Institute of Astronomy, Graduate School of Science, The University of Tokyo, Mitaka, Tokyo 181-0015 (Japan); Murata, Katsuhiro [Department of Astrophysics, Nagoya University, Chikusa-ku, Nagoya 464-8602 (Japan); Nogami, Daisaku [Department of Astronomy, Graduate School of Science, Kyoto University, Kyoto 606-8502 (Japan); and others

    2015-01-10

    We report a new observation of the Jupiter family comet 209P/LINEAR during its 2014 return. The comet is recognized as a dust source of a new meteor shower, the May Camelopardalids. 209P/LINEAR was apparently inactive at a heliocentric distance r{sub h} = 1.6 AU and showed weak activity at r{sub h} ≤ 1.4 AU. We found an active region of <0.001% of the entire nuclear surface during the comet's dormant phase. An edge-on image suggests that particles up to 1 cm in size (with an uncertainty of factor 3-5) were ejected following a differential power-law size distribution with index q = –3.25 ± 0.10. We derived a mass-loss rate of 2-10 kg s{sup –1} during the active phase and a total mass of ≈5 × 10{sup 7} kg during the 2014 return. The ejection terminal velocity of millimeter- to centimeter-sized particles was 1-4 m s{sup –1}, which is comparable to the escape velocity from the nucleus (1.4 m s{sup –1}). These results imply that such large meteoric particles marginally escaped from the highly dormant comet nucleus via the gas drag force only within a few months of the perihelion passage.

  16. Dust from Comet 209P/LINEAR during its 2014 Return: Parent Body of a New Meteor Shower, the May Camelopardalids

    CERN Document Server

    Ishiguro, Masateru; Hanayama, Hidekazu; Takahashi, Jun; Hasegawa, Sunao; Sarugaku, Yuki; Watanabe, Makoto; Imai, Masataka; Goda, Shuhei; Akitaya, Hiroshi; Takagi, Yuhei; Morihana, Kumiko; Honda, Satoshi; Arai, Akira; Sekiguchi, Kazuhiro; Oasa, Yumiko; Saito, Yoshihiko; Morokuma, Tomoki; Murata, Katsuhiro; Nogami, Daisaku; Nagayama, Takahiro; Yanagisawa, Kenshi; Yoshida, Michitoshi; Ohta, Kouji; Kawai, Nobuyuki; Miyaji, Takeshi; Fukushima, Hideo; Watanabe, Jun-ichi; Opitom, Cyrielle; Jehin, Emmanuel; Gillon, Michael; Vaubaillon, Jeremie J

    2014-01-01

    We report a new observation of the Jupiter-family comet 209P/LINEAR during its 2014 return. The comet is recognized as a dust source of a new meteor shower, the May Camelopardalids. 209P/LINEAR was apparently inactive at a heliocentric distance rh = 1.6 au and showed weak activity at rh < 1.4 au. We found an active region of <0.001% of the entire nuclear surface during the comet's dormant phase. An edge-on image suggests that particles up to 1 cm in size (with an uncertainty of factor 3-5) were ejected following a differential power-law size distribution with index q=-3.25+-0.10. We derived a mass loss rate of 2-10 kg/s during the active phase and a total mass of ~5x10^7 kg during the 2014 return. The ejection terminal velocity of millimeter- to centimeter-sized particles was 1-4 m/s, which is comparable to the escape velocity from the nucleus (1.4 m/s). These results imply that such large meteoric particles marginally escaped from the highly dormant comet nucleus via the gas drag force only within a fe...

  17. In vitro screening of reversible and time-dependent inhibition on CYP3A by TM208 and TM209 in rat liver microsomes

    Directory of Open Access Journals (Sweden)

    Miaoran Ning

    2012-04-01

    Full Text Available TM208 and TM209, dithiocarbamate derivatives with potential anti-cancer effects, were evaluated in reversible and time-dependent cytochrome P450 (CYP 3A inhibition assays in rat liver microsomes using testosterone as probe substrate. Both compounds were found to be weak reversible inhibitors and moderate mechanism-based inhibitors of rat CYP3A. For reversible inhibition on rat CYP3A, the Ki values of competitive inhibition model were 12.10±1.75 and 13.94±1.31 μM, respectively. For time-dependent inhibition, the inactivation constants (Kl were 31.93±12.64 and 32.91±15.58 μM, respectively, and the maximum inactivation rates (kinact were 0.03497±0.0069 and 0.07259±0.0172 min−1 respectively. These findings would provide useful in vitro information for future in vivo DDI studies on TM208 or TM209.

  18. 母源性BDE-209暴露对仔鼠海马一氧化氮神经递质的影响%Eeffect of maternal BDE-209 exposure on the Nitric Oxide neurotransmitter in hippocampus of offspring rats

    Institute of Scientific and Technical Information of China (English)

    吴英; 余艳红; 陈敦金

    2012-01-01

    目的 从一氧化氮神经递质角度探讨母源性BDE-209损伤仔鼠神经系统的可能机制.方法 3月龄wistar雌鼠自确定交配成功后随机分为实验组A、B、C、D和对照组E,通过胃灌方法建立自妊娠期至哺乳期的不同剂量BDE-209(100、300、600、1200mg/kg/d)的暴露模型,21天仔鼠断乳后各组随机选取10只仔鼠作为研究对象,应用光电比色法和放射免疫法分别测定各组仔鼠海马组织中一氧化氮(N0)含量、神经元型一氧化氮合成酶( nNOS)活性、环鸟苷酸(cGMP)含量.结果 与对照组E相比,C、D组NO含量和nNOS活性明显增加(P<0.05);B、C、D组cGMP含量明显升高(P<0.05).结论 一定剂量的母源性BDE-209可能通过影响仔鼠NO神经信号递质系统影响其神经认知功能.%Objective: To study the possible mechanism of the damage to nerve system of prenatal and lactational BDE — 209 ( brominated Diphenyl Ethers - 209 ) in offspring rats from the view of Nitric Oxide neurotransmitter system. Methods: After the determination of mate successfully, the female Wistar rats at the age of 3 months were divided in to five groups randomly, so it is the experimental group A, B, C, D and the control group E. Peanut oil suspensions of commercial BDE —209 was given in doses of 100 (group A) , 300 (group B) , 600 (group C) , 1200 (group D) mg/ kg ? D by oral gavage for maternal rats in the experimental groups. The control group (E) was administered only with the same capacity of Peanut oil at the same time. Pick up respectively ten male rats of the fist weaning offspring in each group randomly as the object of our study. We measure the levels of Nitric Oxide (NO) , neuro - nitricoxide synthase (nNOS) and the cyclic guanylic acid (cGMP) in hippocampus tissue of offspring rats by photoelectric colorimetry and radioimmunity in each group. Results: Compared to the offspring rats in control group E, the content of NO and activity of nNOS in the group C and group

  19. Calculation of neutron cross sections for 90Zr, 208Pb and 209Bi in the energy range of 0.5-25 MeV by using the optical model potentials

    International Nuclear Information System (INIS)

    Neutron total cross sections and differential elastic scattering cross sections for the nuclides 90Zr, 208Pb and 209Bi were calculated using different global spherical optical potential (SOP) parameter sets at neutron energies from 0.5-25 MeV. Calculated cross sections for the corresponding nuclides were compared with their experimental data obtained by the EXFOR file to select the best fit parameter sets. It is found that the parameter sets of Ferer Rapaport for 90Zr and Bechetti and Greenless for 208Pb and 209Bi are the best fitted set to obtain the experimental data of total cross sections and angular distributions of these nuclides. (author)

  20. Measurement of the photon proton total cross section at a center-of-mass energy of 209-GeV at HERA

    CERN Document Server

    Chekanov, S; Krakauer, D A; Magill, S; Musgrave, B; Pellegrino, A; Repond, J; Yoshida, R; Mattingly, M C K; Antonioli, P; Bari, G; Basile, M; Bellagamba, L; Boscherini, D; Bruni, A; Bruni, G; Cara Romeo, G; Cifarelli, Luisa; Cindolo, F; Contin, A; Corradi, M; De Pasquale, S; Giusti, P; Iacobucci, G; Levi, G; Margotti, A; Massam, Thomas; Nania, R; Palmonari, F; Pesci, A; Sartorelli, G; Zichichi, A; Aghuzumtsyan, G; Bartsch, D; Brock, I; Crittenden, James Arthur; Goers, S; Hartmann, H; Hilger, E; Irrgang, P; Jakob, H P; Kappes, A; Katz, U F; Kerger, R; Kind, O; Paul, E; Rautenberg, J; Renner, R; Schnurbusch, H; Stifutkin, A; Tandler, J; Voss, K C; Weber, A; Wessoleck, H; Bailey, D S; Brook, N H; Cole, J E; Foster, B; Heath, G P; Heath, H F; Robins, S; Rodrigues, E; Scott, J; Tapper, R J; Wing, M; Capua, M; Mastroberardino, A; Schioppa, M; Susinno, G; Jeoung, H Y; Kim, J Y; Lee, J H; Lim, I T; Ma, K J; Pac, M Y; Caldwell, A; Helbich, M; Liu, X; Mellado, B; Paganis, S; Schmidke, W B; Sciulli, F; Chwastowski, J; Eskreys, Andrzej; Figiel, J; Olkiewicz, K; Przybycien, M B; Stopa, P; Zawiejski, L; Bednarek, B; Grabowska-Bold, I; Jelen, K; Kisielewska, D; Kowal, A M; Kowal, M; Kowal, T; Mindur, B; Rulikowska-Zarebska, E; Suszycki, L; Szuba, D; Szuba, J; Kotanski, Andrzej; Slominski, W; Bauerdick, L A T; Behrens, U; Borras, K; Chiochia, V; Dannheim, D; Desler, K; Drews, G; Fourletova, J; Fox-Murphy, A; Fricke, U; Geiser, A; Göbel, F; Göttlicher, P; Graciani, R; Haas, T; Hain, W; Hartner, G F; Hillert, S; Kötz, U; Kowalski, H; Labes, H; Lelas, D; Löhr, B; Mankel, R; Martens, J; Martínez, M; Moritz, M; Notz, D; Petrucci, M C; Polini, A; Schneekloth, U; Selonke, F; Stonjek, S; Surrow, B; Whitmore, J J; Wichmann, R; Wolf, G; Youngman, C; Zeuner, W; Coldewey, C; López-Duran-Viani, A; Meyer, A; Schlenstedt, S; Barbagli, G; Gallo, E; Genta, C; Pelfer, P G; Bamberger, Andreas; Benen, A; Coppola, N; Markun, P; Raach, H; Wölfle, S; Bell, M; Bussey, Peter J; Doyle, A T; Glasman, C; Hanlon, S; Lee, S W; Lupi, A; McCance, G J; Saxon, D H; Skillicorn, Ian O; Bodmann, B; Holm, U; Salehi, H; Wick, K; Ziegler, A; Carli, T; Gialas, I; Klimek, K; Lohrmann, E; Milite, M; Collins-Tooth, C; Foudas, C; Goncalo, R; Long, K R; Metlica, F; Miller, D B; Tapper, A D; Walker, R; Cloth, P; Filges, D; Kuze, M; Nagano, K; Tokushuku, K; Yamada, S; Yamazaki, Y; Barakbaev, A N; Boos, E G; Pokrovskiy, N S; Zhautykov, B O; Ahn, S H; Lee, S B; Park, S K; Lim, H; Son, D; Barreiro, F; García, G; González, O; Labarga, L; Del Peso, J; Redondo, I; Terron, J; Vázquez, M; Barbi, M; Bertolin, A; Corriveau, F; Ochs, A; Padhi, S; Stairs, D G; Saint-Laurent, M G; Tsurugai, T; Antonov, A; Bashkirov, V; Danilov, P; Dolgoshein, B A; Gladkov, D; Sosnovtsev, V V; Suchkov, S; Dementiev, R K; Ermolov, P F; Golubkov, Yu A; Katkov, I I; Khein, L A; Korotkova, N A; Korzhavina, I A; Kuzmin, V A; Levchenko, B B; Lukina, O Yu; Proskuryakov, A S; Shche, L M; Solomin, A N; Vlasov, N N; Zotkin, S A; Bokel, C; Engelen, J; Grijpink, S; Koffeman, E; Kooijman, P; Maddox, E; Schagen, S; Tassi, E; Tiecke, H G; Tuning, N; Velthuis, J J; Wiggers, L; De Wolf, E; Brümmer, N; Bylsma, B; Durkin, L S; Gilmore, J; Ginsburg, C M; Kim, C L; Ling, T Y; Boogert, S; Cooper-Sarkar, A M; Devenish, R C E; Ferrando, J; Matsushita, T; Rigby, M; Ruske, O; Sutton, M R; Walczak, R; Brugnera, R; Carlin, R; Dal Corso, F; Dusini, S; Garfagnini, A; Limentani, S; Longhin, A; Parenti, A; Posocco, M; Stanco, L; Turcato, M; Adamczyk, L; Oh, B Y; Saull, P R B; Iga, Y; D'Agostini, Giulio; Marini, G; Nigro, A; Cormack, C; Hart, J C; McCubbin, N A; Heusch, C A; Park, I H; Pavel, N; Abramowicz, H; Dagan, S; Gabareen, A; Kananov, S; Kreisel, A; Levy, A; Abe, T; Fusayasu, T; Kohno, T; Umemori, K; Yamashita, T; Hamatsu, R; Hirose, T; Inuzuka, M; Kitamura, S; Matsuzawa, K; Nishimura, T; Arneodo, M; Cartiglia, N; Cirio, R; Costa, M; Ferrero, M I; Maselli, S; Monaco, V; Peroni, C; Ruspa, M; Sacchi, R; Solano, A; Staiano, A; Galea, R; Koop, T; Levman, G M; Martin, J F; Mirea, A; Sabetfakhri, A; Butterworth, J M; Gwenlan, C; Hall-Wilton, R; Hayes, M E; Heaphy, E A; Jones, T W; Lane, J B; Lightwood, M S; West, B J; Ciborowski, J; Ciesielski, R; Grzelak, G; Nowak, R J; Pawlak, J M; Smalska, B; Sztuk, J; Tymieniecka, T; Ukleja, A; Ukleja, J; Zakrzewski, J A; Adamus, M; Plucinsky, P P; Eisenberg, Y; Gladilin, L K; Hochman, D; Karshon, U; Breitweg, J; Chapin, D; Cross, R; Kcira, D; Lammers, S; Reeder, D D; Savin, A A; Smith, W H; Deshpande, A A; Dhawan, S; Hughes, V W; Straub, P B; Bhadra, S; Catterall, C D; Fourletov, S; Menary, S R; Soares, M; Standage, J

    2002-01-01

    The photon-proton total cross section has been measured in the process e+ p -> e+ gamma p -> e+ X with the ZEUS detector at HERA. Events were collected with photon virtuality Q^2 < 0.02 GeV^2 and average gamma-p center-of-mass energy W_{gamma p} = 209 GeV in a dedicated run, designed to control systematic effects, with an integrated luminosity of 49 nb^{-1}. The measured total cross section is sigma_{tot}^{gamma p} = 174 +- 1 (stat.) +- 13 (syst.) microbarns. The energy dependence of the cross section is compatible with parameterizations of high-energy p-p and p-pbar data.

  1. Tests of the Standard Model and Constraints on New Physics from Measurements of Fermion-Pair Production at 189-209 GeV at LEP

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Arcelli, S; Asai, S; Axen, D A; Azuelos, Georges; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brigliadori, L; Brown, R M; Büsser, K; Burckhart, H J; Campana, S; Carnegie, R K; Caron, B; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, Akos; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Feld, L; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Fürtjes, A; Gagnon, P; Gary, J W; Gaycken, G; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, Richard J; Hensel, C; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanaya, N; Kanzaki, J; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, Richard K; Kellogg, R G; Kennedy, B W; Klein, K; Klier, A; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kormos, L L; Kramer, T; Krieger, P; Von Krogh, J; Krüger, K; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Layter, J G; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; MacPherson, A; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Mashimo, T; Mättig, P; McDonald, W J; McKenna, J A; McMahon, T J; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Michelini, Aldo; Mihara, S; Mikenberg, G; Miller, D J; Moed, S; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Okpara, A N; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Poli, B; Polok, J; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rosati, S; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Schwick, C; Scott, W G; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Stephens, K; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Waller, D; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wetterling, D; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2004-01-01

    Cross-section and angular distributions for hadronic and lepton-pair final states in e+e- collisions at centre-of-mass energies between 189 GeV and 209 GeV, measured with the OPAL detector at LEP, are presented and compared with the predictions of the Standard Model. The measurements are used to determine the electromagnetic coupling constant alphaem at LEP2 energies. In addition, the results are used together with OPAL measurements at 91-183 GeV within the S-matrix formalism to determine the gamma-Z interference term and to make an almost model-independent measurement of the Z mass. Limits on extensions to the Standard Model described by effective four-fermion contact interactions or the addition of a heavy Z boson are also presented.

  2. Study of Z Pair Production and Anomalous Couplings in $e^+ e^-$ Collisions at $\\sqrt{s}$ between 190 GeV and 209 GeV

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Arcelli, S; Asai, S; Axen, D A; Azuelos, Georges; Bailey, I; Barberio, E; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brigliadori, L; Brown, R M; Büsser, K; Burckhart, H J; Campana, S; Carnegie, R K; Caron, B; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Csilling, A; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Feld, L; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Fürtjes, A; Gagnon, P; Gary, J W; Gaycken, G; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harder, K; Harel, A; Harin-Dirac, M; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, R J; Hensel, C; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanaya, N; Kanzaki, J; Karapetian, G V; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kim, D H; Klein, K; Klier, A; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kormos, L L; Kramer, T; Krieger, P; Von Krogh, J; Krüger, K; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Layter, J G; Leins, A; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, J; MacPherson, A; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Mashimo, T; Mättig, P; McDonald, W J; McKenna, J A; McMahon, T J; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Moed, S; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Okpara, A N; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Patrick, G N; Pilcher, J E; Pinfold, J L; Plane, D E; Poli, B; Polok, J; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Rick, H; Roney, J M; Rosati, S; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Schwick, C; Scott, W G; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Siroli, G P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Stephens, K; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Taylor, R J; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Waller, D; Ward, C P; Ward, D R; Warsinsky, M; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wetterling, D; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2003-01-01

    A study of Z-boson pair production in e+e- annihilation at center-of-mass energies between 190 GeV and 209 GeV is reported. Final states containing only leptons, (l+l-l+l- and l+l-nn), quark and lepton pairs, (qql+l-, qqnn) and only hadrons (qqqq) are considered. In all states with at least one Z boson decaying hadronically, lifetime, lepton and event-shape tags are used to separate bb pairs from qq final state. Limits on anomalous ZZgamma and ZZZ couplings are derived from the measured cross sections and from event kinematics using an optimal observable method. Limits on low scale gravity with large dimensions are derived from the cross sections and their dependence on polar angle.

  3. Search for Neutral Higgs Bosons of the Minimal Supersymmetric Standard Model in $e^{+}e^{-}$ Interactions at $\\sqrt{s}$ up to 209 GeV

    CERN Document Server

    Achard, P; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Anderhub, H; Andreev, V P; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, G; Baksay, L; Baldew, S V; Banerjee, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Biasini, M; Biglietti, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bottai, S; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Chamizo-Llatas, M; Chang, Y H; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; de la Cruz, B; Cucciarelli, S; van Dalen, J A; De Asmundis, R; Déglon, P L; Debreczeni, J; Degré, A; Dehmelt, K; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Dionisi, C; Dittmar, Michael; Doria, A; Dova, M T; Duchesneau, D; Echenard, B; Eline, A; El-Mamouni, H; Engler, A; Eppling, F J; Ewers, A; Extermann, Pierre; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisher, W; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gentile, S; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hakobyan, R S; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hirschfelder, J; Hofer, H; Hohlmann, M; Holzner, G; Hou, S R; Hu, Y; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, J K; Kirkby, Jasper; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Levtchenko, M; Levchenko, P M; Li, C; Likhoded, S A; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luminari, L; Lustermann, W; Ma Wen Gan; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Nagy, S; Natale, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Ofierzynski, R A; Organtini, G; Palomares, C; Pandoulas, D; Paolucci, P; Paramatti, R; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pioppi, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Pothier, J; Prokofiev, D O; Prokofev, D; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Roux, B; Rubio, Juan Antonio; Ruggiero, G; Rykaczewski, H; Sakharov, A; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Souga, C; Spillantini, P; Steuer, M; Stickland, D P; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S V; Suter, H; Swain, J D; Szillási, Z; Tang, X W; Tarjan, P; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Ulbricht, J; Valente, E; Van de Walle, R T; Vásquez, R P; Veszpremi, V; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Wadhwa, M; Wallraff, W; Wang, X L; Wang, Z M; Weber, M; Wienemann, P; Wilkens, H; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhao, J; Zhu, G Y; Zhu, R Y; Zhuang, H L; Zichichi, A; Zimmermann, B; Zöller, M

    2002-01-01

    A search for the lightest neutral CP-even and neutral CP-odd Higgs bosons of the Minimal Supersymmetric Standard Model is performed using 216.6 pb-1 of data collected with the L3 detector at LEP at centre-of-mass energies between 203 and 209 GeV. No indication of a signal is found. Including our results from lower centre-of-mass energies, lower limits on the Higgs boson masses are set as a function of tan(beta) for several scenarios. For tan(beta) greater than 0.7 they are mh > 84.5 GeV and mA > 86.3 GeV at 95% confidence level.

  4. Search for pair-produced leptoquarks in $e^{+}e^{-}$ interactions at $\\sqrt{s}\\simeq$ 189 -209 GeV

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Arcelli, S; Asai, S; Axen, D A; Azuelos, Georges; Bailey, I; Barberio, E; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Bock, P; Boeriu, O; Boutemeur, M; Braibant, S; Brigliadori, L; Brown, R M; Burckhart, H J; Büsser, K; Campana, S; Carnegie, R K; Caron, B; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Csilling, Akos; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Feld, L; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Fürtjes, A; Gagnon, P; Gary, J W; Gaycken, G; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Hajdu, C; Hamann, M; Hanson, G G; Harder, K; Harel, A; Harin-Dirac, M; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, Richard J; Hensel, C; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanaya, N; Kanzaki, J; Karapetian, G V; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, Richard K; Kellogg, R G; Kennedy, B W; Kim, D H; Klein, K; Klier, A; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kormos, L L; Krämer, T; Krieger, P; Von Krogh, J; Krüger, K; Kupper, M; Kühl, T; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Layter, J G; Leins, A; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, J; MacPherson, A; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Mashimo, T; McDonald, W J; McKenna, J A; McMahon, T J; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Michelini, Aldo; Mihara, S; Mikenberg, G; Miller, D J; Moed, S; Mohr, W; Mori, T; Mutter, A; Mättig, P; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Okpara, A N; Oreglia, M J; Orito, S; Pahl, C; Pater, J R; Patrick, G N; Pilcher, J E; Pinfold, J L; Plane, D E; Poli, B; Polok, J; Pooth, O; Przybycien, M B; Pásztor, G; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rosati, S; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schröder, M; Schumacher, M; Schwick, C; Schörner-Sadenius, T; Scott, W G; Sen-Gupta, A; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Siroli, G P; Skuja, A; Smith, A M; Sobie, R J; Spanó, F; Stahl, A; Stephens, K; Strom, D; Ströhmer, R; Söldner-Rembold, S; Tarem, S; Tasevsky, M; Taylor, R J; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vannerem, P; Vertesi, R; Verzocchi, M; Vollmer, C F; Voss, H; Vossebeld, Joost Herman; Waller, D; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wetterling, D; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2003-01-01

    A search for pair-produced leptoquarks is performed using e+e- collision events collected by the OPAL detector at LEP at centre-of-mass energies between 189 and 209 GeV. The data sample corresponds to a total integrated luminosity of 596 pb^-1. The leptoquarks are assumed to be produced via couplings to the photon and the Z0. For a given search channel only leptoquark decays involving a single lepton generation are considered. No evidence for leptoquark pair production is observed. Lower limits on masses for scalar and vector leptoquarks are calculated. The results improve most of the LEP limits derived from previous searches for the pair production process by 10-25 GeV, depending on the leptoquark quantum numbers.

  5. The damping of the single-particle proton strengths in 1isub(11/2) and 1jsub(15/2) states of 209Bi

    International Nuclear Information System (INIS)

    15 proton states have been mixed with the low-lying vibrational states as well as the vibrational states arising from the giant resonances in 208Pb to search for the broad fragmentations of the 1 'one' j15/2 and 'one' i11/2 states as observed in the most recent (α,t) reaction on 208Pb. The distribution of the shell-model strengths of these two high-spin states can be explained on the basis of the core polarisation effect on these two proton states of 209Bi. Knowledge of the altered shell-model energies of the proton states of 208Pb is necessary for the search for magicity in the superheavy nuclei. (author)

  6. Measurement of event shape distributions and moments in $e^{+}e^{-} \\to$ hadrons at 91-209 GeV and a determination of $\\alpha_{s}$

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Asai, S; Axen, D A; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brown, R M; Burckhart, H J; Campana, S; Capiluppi, P; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, R J; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanzaki, J; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krieger, P; Von Krogh, J; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Mashimo, T; Mättig, P; McKenna, J A; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rossi, A M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L; CERN. Geneva

    2005-01-01

    We have studied hadronic events from e+e- annihilation data at centre-of-mass energies from 91 to 209 GeV. We present distributions of event shape observables and their moments at each energy and compare with QCD Monte Carlo models. From the event shape distributions we extract the strong coupling alpha_s and test its evolution with energy scale. The results are consistent with the running of alpha_s expected from QCD. Combining all data, the value of alpha_s (M_z) is determined to be alpha_s(Mz)=0.1191+-0.0005(stat.)+-0.0010 (expt.)+-0.0011(hadr.)+-0.0044(theo.) The energy evolution of the moments is also used to determine a value of alpha_ with slightly larger errors: alpha_s(Mz)=0.1223+-0.0005(stat.) +-0.0014(expt.) +-0.0016(hadr.) +0.0054 -0.0036 (theo).

  7. Neutron-induced fission cross section of (nat)Pb and (209)Bi from threshold to 1 GeV: An improved parametrization

    CERN Document Server

    Tarrio, D; Audouin, L; Berthier, B; Duran, I; Ferrant, L; Isaev, S; Le Naour, C; Paradela, C; Stephan, C; Trubert, D; Abbondanno, U; Aerts, G; Alvarez-Velarde, F; Andriamonje, S; Andrzejewski, J; Assimakopoulos, P; Badurek, G; Baumann, P; Becvar, F; Belloni, F; Berthoumieux, E; Calvino, F; Calviani, M; Cano-Ott, D; Capote, R; Carrapico, C; Carrillo de Albornoz, A; Cennini, P; Chepel, V; Chiaveri, E; Colonna, N; Cortes, G; Couture, A; Cox, J; Dahlfors, M; David, S; Dillmann, I; Dolfini, R; Domingo-Pardo, C; Dridi, W; Eleftheriadis, C; Embid-Segura, M; Ferrari, A; Ferreira-Marques, R; Fitzpatrick, L; Frais-Koelbl, H; Fujii, K; Furman, W; Goncalves, I; Gonzalez-Romero, E; Goverdovski, A; Gramegna, F; Griesmayer, E; Guerrero, C; Gunsing, F; Haas, B; Haight, R; Heil, M; Herrera-Martinez, A; Igashira, M; Jericha, E; Kadi, Y; Kappeler, F; Karadimos, D; Karamanis, D; Kerveno, M; Ketlerov, V; Koehler, P; Konovalov, V; Kossionides, E; Krticka, M; Lampoudis, C; Leeb, H; Lederer, C; Lindote, A; Lopes, I; Losito, R; Lozano, M; Lukic, S; Marganiec, J; Marques, L; Marrone, S; Martinez, T; Massimi, C; Mastinu, P; Mendoza, E; Mengoni, A; Milazzo, P.M; Moreau, C; Mosconi, M; Neves, F; Oberhummer, H; O'Brien, S; Oshima, M; Pancin, J; Papachristodoulou, C; Papadopoulos, C; Patronis, N; Pavlik, A; Pavlopoulos, P; Perrot, L; Pigni, M.T; Plag, R; Plompen, A; Plukis, A; Poch, A; Praena, J; Pretel, C; Quesada, J; Rauscher, T; Reifarth, R; Rosetti, M; Rubbia, C; Rudolf, G; Rullhusen, P; Salgado, J; Santos, C; Sarchiapone, L; Sarmento, R; Savvidis, I; Tagliente, G; Tain, J.L; Tavora, L; Terlizzi, R; Vannini, G; Vaz, P; Ventura, A; Villamarin, D; Vlachoudis, V; Vlastou, R; Voss, F; Walter, S; Wendler, H; Wiescher, M; Wisshak, K

    2011-01-01

    Neutron-induced fission cross sections for (nat)Pb and (209)Bi were measured with a white-spectrum neutron source at the CERN Neutron Time-of-Flight (n\\_TOF) facility. The experiment, using neutrons from threshold up to 1 GeV, provides the first results for these nuclei above 200 MeV. The cross sections were measured relative to (235)U and (238)U in a dedicated fission chamber with parallel plate avalanche counter detectors. Results are compared with previous experimental data. Upgraded parametrizations of the cross sections are presented, from threshold energy up to 1 GeV. The proposed new sets of fitting parameters improve former results along the whole energy range.

  8. Comparison of reactions for the production of 258,257Db: 208Pb(51V,xn) and 209Bi(50Ti,xn)

    OpenAIRE

    Gates, Jacklyn M.

    2008-01-01

    Excitation functions for the 1n and 2n exit channels of the 208Pb(51V,xn)259-xDb reaction were measured. A maximum cross section of the 1n exit channel of 2070+1100/-760 pb was measured at an excitation energy of 16.0 +- 1.8 MeV. For the 2n exit channel, a maximum cross section of 1660+450/-370 pb was measured at 22.0 +- 1.8 MeV excitation energy. The 1n excitation function for the 209Bi(50Ti,n)258Db reaction was remeasured, resulting in a cross section of 5480+1750/-1370 pb at an excitati...

  9. Search for a fourth generation b'-quark at LEP-II at sqrt{s}=196-209 GeV

    CERN Document Server

    Abdallah, J; Adam, W; Adzic, P; Albrecht, T; Alemany-Fernandez, R; Allmendinger, T; Allport, P P; Amaldi, Ugo; Amapane, N; Amato, S; Anashkin, E; Andreazza, A; Andringa, S; Anjos, N; Antilogus, P; Apel, W D; Arnoud, Y; Ask, S; Åsman, B; Augustin, J E; Augustinus, A; Baillon, P; Ballestrero, A; Bambade, P; Barbier, R; Bardin, D; Barker, G J; Baroncelli, A; Battaglia, M; Baubillier, M; Becks, K H; Begalli, M; Behrmann, A; Ben-Haim, E; Benekos, N; Benvenuti, A; Bérat, C; Berggren, M; Berntzon, L; Bertrand, D; Besançon, M; Besson, N; Bloch, D; Blom, M; Bluj, M; Bonesini, M; Boonekamp, M; Booth, P S L; Borisov, G; Botner, O; Bouquet, B; Bowcock, T J V; Boyko, I; Bracko, M; Brenner, R; Brodet, E; Brückman, P; Brunet, J M; Buschbeck, B; Buschmann, P; Calvi, M; Camporesi, T; Canale, V; Carena, F; Castro, N; Cavallo, F; Chapkin, M; Charpentier, P; Checchia, P; Chierici, R; Shlyapnikov, P; Chudoba, J; Chung, S U; Cieslik, K; Collins, P; Contri, R; Cosme, G; Cossutti, F; Costa, M J; Crennell, D J; Cuevas-Maestro, J; D'Hondt, J; Dalmau, J; Da Silva, T; Da Silva, W; Della Ricca, G; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Maria, N; De Min, A; De Paula, L; Di Ciaccio, L; Di Simone, A; Doroba, K; Drees, J; Eigen, G; Ekelöf, T J C; Ellert, M; Elsing, M; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Feindt, M; Fernández, J; Ferrer, A; Ferro, F; Flagmeyer, U; Föth, H; Fokitis, E; Fulda-Quenzer, F; Fuster, J; Gandelman, M; García, C; Gavillet, P; Gazis, E; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; Graziani, E; Grosdidier, G; Grzelak, K; Guy, J; Haag, C; Hallgren, A; Hamacher, K; Hamilton, K; Haug, S; Hauler, F; Hedberg, V; Hennecke, M; Herr, H; Hoffman, J; Holmgren, S O; Holt, P J; Houlden, M A; Jackson, J N; Jarlskog, G; Jarry, P; Jeans, D; Johansson, E K; Johansson, P D; Jonsson, P; Joram, C; Jungermann, L; Kapusta, F; Katsanevas, S; Katsoufis, E; Kernel, G; Kersevan, B P; Kerzel, U; King, B T; Kjaer, N J; Kluit, P; Kokkinias, P; Kourkoumelis, C; Kuznetsov, O; Krumshtein, Z; Kucharczyk, M; Lamsa, J; Leder, G; Ledroit, F; Leinonen, L; Leitner, R; Lemonne, J; Lepeltier, V; Lesiak, T; Liebig, W; Liko, D; Lipniacka, A; Lopes, J H; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Malek, A; Maltezos, S; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Mazzucato, M; Mönig, K; Mulders, M; Nawrocki, K; Olshevskii, A G; Masik, J; McNulty, R; Mastroyiannopoulos, N; Migliore, E; Matorras, F; Matteuzzi, C; Mazzucato, F; Moch, M; Montenegro, J; Moraes, D; Moreno, S; Morettini, P; Müller, U; Münich, K; Murray, W; Monge, R; Orava, R; Muryn, B; Österberg, K; Myatt, G; Myklebust, T; Nassiakou, M; Oliveira, O; Paganoni, M; Navarria, F; Nikolenko, M; Oblakowska-Mucha, A; Ouraou, A; Obraztsov, V F; Oyanguren, A; Oliveira, S M; Paiano, S; Meroni, C; Mitaroff, W A; Mjörnmark, U; Moa, T; Mundim, L; Onofre, A; Nicolaidou, R; Palacios, J P; Palka, H; Papadopoulou, T D; Pape, L; Parkes, C; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Peralta, L; Perepelitsa, V; Perrotta, A; Petrolini, A; Piedra, J; Pieri, L; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Poireau, V; Pol, M E; Polok, G; Pozdnyakov, V; Pukhaeva, N; Pullia, A; Rames, J; Read, A; Rebecchi, P; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Richard, F; Rídky, J; Rivero, M; Rodríguez, D; Romero, A; Ronchese, P; Roudeau, P; Rovelli, T; Ruhlmann-Kleider, V; Ryabtchikov, D; Sadovskii, A; Siebel, M; Stanitzki, M; Salmi, L; Stocchi, A; Salt, J; Sander, C; Stugu, B; Santos, R; Savoy-Navarro, A; Sopczak, A; Szeptycka, M; Schwickerath, U; Sosnowski, R; Szumlak, T; Sekulin, R; Spassoff, Tz; Tabarelli de Fatis, T; Sisakian, A; Smadja, G; Strauss, J; Smirnova, O; Sokolov, A; Szczekowski, M; Taffard, A C; Tegenfeldt, F; Timmermans, J; Tkatchev, L; Tobin, M; Todorovova, S; Tomé, B; Tonazzo, A; Tortosa, P; Travnicek, P; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M L; Tyapkin, I A; Tyapkin, P; Tzamarias, S; Uvarov, V; Valenti, G; van Dam, P; Van Eldik, J; Van Remortel, N; Van Vulpen, I; Vegni, G; Veloso, F; Venus, W; Verdier, P; Verzi, V; Vilanova, D; Vitale, L; Vrba, V; Wahlen, H; Washbrook, A J; Weiser, C; Wicke, D; Wickens, J; Wilkinson, G; Winter, M; Witek, M; Yushchenko, O; Zalewska-Bak, A; Zalewski, P; Zavrtanik, D; Zhuravlov, V; Zimin, N I; Zintchenko, A; Zupan, M

    2007-01-01

    A search for the pair production of fourth generation b'-quarks was performed using data taken by the DELPHI detector at LEP-II. The analysed data were collected at centre-of-mass energies ranging from 196 to 209 GeV, corresponding to an integrated luminosity of 420 pb^{-1}. No evidence for a signal was found. Upper limits on BR(b' -> bZ) and BR(b' -> cW) were obtained for b' masses ranging from 96 to 103 GeV/c^2. These limits, together with the theoretical branching ratios predicted by a sequential four generations model, were used to constrain the value of R_{CKM}=|V_{cb'}/V_{tb'}V_{tb}|, where V_{cb'}, V_{tb'} and V_{tb} are elements of the extended CKM matrix.

  10. Dynamical decay process of {sup 219,} {sup 220}Ra{sup *} formed in {sup 10,} {sup 11}B+{sup 209}Bi reactions

    Energy Technology Data Exchange (ETDEWEB)

    Sawhney, G.; Sharma, M.K. [Thapar University, School of Physics and Materials Science, Punjab (India)

    2012-05-15

    The excitation functions for both the evaporation residue and fission have been calculated for {sup 10}B +{sup 209}Bi and {sup 11}B+{sup 209}Bi reactions forming compound systems {sup 219,220}Ra{sup *}, using the dynamical cluster-decay model (DCM) with effects of deformations and orientations of the nuclei included in it. In addition to this, the excitation functions for complete fusion (CF) are obtained by summing the fission cross-sections, neutron evaporation and charged particle evaporation residue cross-sections produced through the {alpha}xn and pxn (x = 2, 3, 4) emission channels for the {sup 219}Ra system at various incident centre-of-mass energies. Experimentally the CF cross-sections are suppressed and the observed suppression is attributed to the low binding energy of {sup 10,11}B which breaks up into charged fragments. The reported complete fusion (CF) and incomplete fusion (ICF) excitation functions for the {sup 219}Ra system are found to be nicely fitted by the calculations performed in the framework of DCM, without invoking a significant contribution from quasi-fission. Although DCM has been applied for a number of compound nucleus decay studies in the recent past, the same is being used here in reference to ICF and subsequent decay processes along with the CF process. Interestingly the main contribution to complete fusion cross-section comes from the fission cross-section at higher incident energies, which in DCM is found to consist of an asymmetric fission window, shown to arise due to the deformation and orientation effects of formation and decay fragments. (orig.)

  11. Determination of the neutron resonance parameters for 206Pb and of the thermal neutron capture cross section for 206Pb and 209Bi

    International Nuclear Information System (INIS)

    Chapter 1 describes the motivation of the measurements (accelerator driven systems, stellar nucleosynthesis, neutron induced reactions on 206Pb), the present status of the neutron capture data for 206Pb and 209Bi and the structure of this work. In Chapter 2 the basic reaction theory underlying this work is described. The neutron induced reaction mechanism and formalism are explained. The parameterisation of the cross section in terms of R-matrix theory is discussed and we put particular emphasis on the statistical behaviour of the resonance parameters and the impact of the angular distribution of gamma rays following neutron capture. The relation between experimental observables and the resonance parameters is discussed together with general comments related to resonance shape analysis. Chapter 3 is focused on the determination of resonance parameters for 206Pb. We performed high-resolution transmission and capture measurements at the Time-Of-Flight (TOF) facility GELINA of the IRMM at Geel (B) and determined the resonance parameters. For nuclei like 206Pb, where the total width is dominated by Γn, the capture area allows to determine G. Transmission measurements were carried out to determine Γn, and the statistical factor g of resonances. Before performing a Resonance Shape Analysis (RSA) on the transmission and capture data, we verified the neutron flux and resolution at GELINA. We also compared the characteristics of GELINA with those of the n-TOF facility at CERN. A special emphasis is placed on the total energy detection technique using C6D6 detectors. This technique was applied for the determination of the capture cross section. To reduce systematic bias effects on the capture cross section, the response of the detectors was determined by Monte Carlo simulations, which has been validated by experiments. Using these response functions the partial capture cross sections for individual resonances of 206Pb have been deduced, by unfolding the response of the C6D

  12. Effect of gamma radiation on electrical and optical properties of (TeO2)0.9 (In2O3)0.1 thin films

    Indian Academy of Sciences (India)

    S L Sharma; T K Maity

    2011-02-01

    We have studied in detail the gamma radiation induced changes in the electrical properties of the (TeO2)0.9 (In2O3)0.1 thin films of different thicknesses, prepared by thermal evaporation in vacuum. The current–voltage characteristics for the as-deposited and exposed thin films were analysed to obtain current versus dose plots at different applied voltages. These plots clearly show that the current increases quite linearly with the radiation dose over a wide range and that the range of doses is higher for the thicker films. Beyond certain dose (a quantity dependent on the film thickness), however, the current has been observed to decrease. In order to understand the dose dependence of the current, we analysed the optical absorption spectra for the as-deposited and exposed thin films to obtain the dose dependences of the optical bandgap and energy width of band tails of the localized states. The increase of the current with the gamma radiation dose may be attributed partly to the healing effect and partly to the lowering of the optical bandgap. Attempts are on to understand the decrease in the current at higher doses. Employing dose dependence of the current, some real-time gamma radiation dosimeters have been prepared, which have been found to possess sensitivity in the range 5–55 Gy/A/cm2. These values are far superior to any presently available real-time gamma radiation dosimeter.

  13. Di-Jet Production in Photon-Photon colisions at $\\sqrt{s_{ee}}$ from 189 to 209 GeV

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, Gideon; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Arcelli, S; Asai, S; Axen, D A; Azuelos, Georges; Bailey, I; Barberio, E; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Bloodworth, Ian J; Boeriu, O; Bock, P; Bonacorsi, D; Boutemeur, M; Braibant, S; Brigliadori, L; Brown, R M; Büsser, K; Burckhart, H J; Campana, S; Carnegie, R K; Caron, B; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Csilling, Akos; Cuffiani, M; Dado, S; Dallison, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Elfgren, E; Etzion, E; Fabbri, Franco Luigi; Feld, L; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Fürtjes, A; Gagnon, P; Gary, J W; Gaycken, G; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harder, K; Harel, A; Harin-Dirac, M; Hauschild, M; Hauschildt, J; Hawkes, C M; Hawkings, R; Hemingway, Richard J; Hensel, C; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Homer, R James; Horváth, D; Howard, R; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanaya, N; Kanzaki, J; Karapetian, G V; Karlen, D A; Kartvelishvili, V G; Kawagoe, K; Kawamoto, T; Keeler, Richard K; Kellogg, R G; Kennedy, B W; Kim, D H; Klein, K; Klier, A; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kormos, L L; Krämer, T; Kress, T; Krieger, P; Von Krogh, J; Krop, D; Krüger, K; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Layter, J G; Leins, A; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, J; MacPherson, A; Mader, W; Marcellini, S; Marchant, T E; Martin, A J; Martin, J P; Masetti, G; Mashimo, T; Mättig, P; McDonald, W J; McKenna, J A; McMahon, T J; McPherson, R A; Meijers, F; Méndez-Lorenzo, P; Menges, W; Merritt, F S; Mes, H; Michelini, Aldo; Mihara, S; Mikenberg, G; Miller, D J; Moed, S; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Okpara, A N; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Patrick, G N; Pilcher, J E; Pinfold, James L; Plane, D E; Poli, B; Polok, J; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Rick, Hartmut; Roney, J M; Rosati, S; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sahr, O; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Schwick, C; Scott, W G; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Siroli, G P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Stephens, K; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Taylor, R J; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trefzger, T M; Tricoli, A; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vachon, B; Vollmer, C F; Vannerem, P; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Waller, D; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wetterling, D; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2003-01-01

    Di-jet producion is studied in collisions of quasi-real photons at e+e- centre- of-mass energies sqrt(s)ee from 189 to 209 GeV at LEP. The data were collected with the OPAL detector. Jets are reconstructed using an inclusive k_t clustering algorithm for all cross-section measurements presented. A cone jet algorithm is used in addition to study the different structure of the jets resulting from either of the algorithms. The inclusive di-jet cross-section is measured as a function of the mean transverse energy Etm(jet) of the two leading jets, and as a functiuon of the estimated fraction of the photon momentum carried by the parton entering the hard sub-process, xg, for different regions of Etm (jet). Angular distribution in di-jet events are measured and used to demonstrate the dominance of quark and gluon initiated processes in different regions of phase space. Furthermore the inclusive di-jet cross-section as a function of |eta(jet)| and |delta eta (jet)| is presented where eta(jet) is the jet pseudo-rapidit...

  14. Scaling violations of quark and gluon jet fragmentation functions in $e^{+}e{-}$ annihilations at $\\sqrt{s}$ = 91.2 and 183-209 GeV

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Asai, S; Axen, D A; Azuelos, Georges; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brigliadori, L; Brown, R M; Büsser, K; Burckhart, H J; Campana, S; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, Akos; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Feld, L; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Gaycken, G; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, Richard J; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanaya, N; Kanzaki, J; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, Richard K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krieger, P; Von Krogh, J; Krüger, K; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Layter, J G; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Mashimo, T; Mättig, P; McKenna, J A; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, Aldo; Mihara, S; Mikenberg, G; Miller, D J; Moed, S; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Poli, B; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Scott, W G; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2004-01-01

    Flavour inclusive, udsc and b fragmentation functions in unbiased jets, and flavour inclusive, udsc, b and gluon fragmentation functions in biased jets are measured in e+e- annihilations from data collected at centre-of-mass energies of 91.2, and 183-209 GeV with the OPAL detector at LEP. The unbiased jets are defined by hemispheres of inclusive hadronic events, while the biased jet measurements are based on three-jet events selected with jet algorithms. Several methods are employed to extract the fragmentation functions over a wide range of scales. Possible biases are studied in the results are obtained. The fragmentation functions are compared to results from lower energy e+e- experiments and with earlier LEP measurements and are found to be consistent. Scaling violations are observed and are found to be stronger for the fragmentation functions of gluon jets than for those of quarks. The measured fragmentation functions are compared to three recent theoretical next-to-leading order calculations and to the p...

  15. Multi-Photon Events with Large Missing Energy in $e^{+}e^{-}$ Collisions at $\\sqrt{s}=192-209 GeV$

    CERN Document Server

    Abbiendi, G; Åkesson, P F; Alexander, G; Allison, J; Amaral, P; Anagnostou, G; Anderson, K J; Arcelli, S; Asai, S; Axen, D A; Azuelos, Georges; Bailey, I; Barberio, E; Barillari, T; Barlow, R J; Batley, J Richard; Bechtle, P; Behnke, T; Bell, K W; Bell, P J; Bella, G; Bellerive, A; Benelli, G; Bethke, Siegfried; Biebel, O; Boeriu, O; Bock, P; Boutemeur, M; Braibant, S; Brigliadori, L; Brown, R M; Büsser, K; Burckhart, H J; Campana, S; Carnegie, R K; Carter, A A; Carter, J R; Chang, C Y; Charlton, D G; Ciocca, C; Csilling, A; Cuffiani, M; Dado, S; de Roeck, A; De Wolf, E A; Desch, Klaus; Dienes, B; Donkers, M; Dubbert, J; Duchovni, E; Duckeck, G; Duerdoth, I P; Etzion, E; Fabbri, Franco Luigi; Feld, L; Ferrari, P; Fiedler, F; Fleck, I; Ford, M; Frey, A; Gagnon, P; Gary, J W; Gaycken, G; Geich-Gimbel, C; Giacomelli, G; Giacomelli, P; Giunta, M; Goldberg, J; Gross, E; Grunhaus, Jacob; Gruwé, M; Günther, P O; Sen-Gupta, A; Hajdu, C; Hamann, M; Hanson, G G; Harel, A; Hauschild, M; Hawkes, C M; Hawkings, R; Hemingway, R J; Herten, G; Heuer, R D; Hill, J C; Hoffman, K; Horváth, D; Igo-Kemenes, P; Ishii, K; Jeremie, H; Jovanovic, P; Junk, T R; Kanaya, N; Kanzaki, J; Karlen, Dean A; Kawagoe, K; Kawamoto, T; Keeler, R K; Kellogg, R G; Kennedy, B W; Kluth, S; Kobayashi, T; Kobel, M; Komamiya, S; Kramer, T; Krieger, P; Von Krogh, J; Krüger, K; Kühl, T; Kupper, M; Lafferty, G D; Landsman, Hagar Yaël; Lanske, D; Layter, J G; Lellouch, D; Letts, J; Levinson, L; Lillich, J; Lloyd, S L; Loebinger, F K; Lü, J; Ludwig, A; Ludwig, J; Mader, W; Marcellini, S; Martin, A J; Masetti, G; Mashimo, T; Mättig, P; McKenna, J A; McPherson, R A; Meijers, F; Menges, W; Merritt, F S; Mes, H; Meyer, N; Michelini, A; Mihara, S; Mikenberg, G; Miller, D J; Moed, S; Mohr, W; Mori, T; Mutter, A; Nagai, K; Nakamura, I; Nanjo, H; Neal, H A; Nisius, R; O'Neale, S W; Oh, A; Oreglia, M J; Orito, S; Pahl, C; Pásztor, G; Pater, J R; Pilcher, J E; Pinfold, J L; Plane, D E; Poli, B; Pooth, O; Przybycien, M B; Quadt, A; Rabbertz, K; Rembser, C; Renkel, P; Roney, J M; Rozen, Y; Runge, K; Sachs, K; Saeki, T; Sarkisyan-Grinbaum, E; Schaile, A D; Schaile, O; Scharff-Hansen, P; Schieck, J; Schörner-Sadenius, T; Schröder, M; Schumacher, M; Scott, W G; Seuster, R; Shears, T G; Shen, B C; Sherwood, P; Skuja, A; Smith, A M; Sobie, R J; Söldner-Rembold, S; Spanó, F; Stahl, A; Strom, D; Ströhmer, R; Tarem, S; Tasevsky, M; Teuscher, R; Thomson, M A; Torrence, E; Toya, D; Tran, P; Trigger, I; Trócsányi, Z L; Tsur, E; Turner-Watson, M F; Ueda, I; Ujvári, B; Vollmer, C F; Vannerem, P; Vertesi, R; Verzocchi, M; Voss, H; Vossebeld, Joost Herman; Ward, C P; Ward, D R; Watkins, P M; Watson, A T; Watson, N K; Wells, P S; Wengler, T; Wermes, N; Wilson, G W; Wilson, J A; Wolf, G; Wyatt, T R; Yamashita, S; Zer-Zion, D; Zivkovic, L

    2004-01-01

    Events with a final state consisting of two or more photons and large missing transverse energy have been observed in e+e- collisions at centre-of-mass energies in the range 192 - 209 GeV using the OPAL detector at LEP. Cross-section measurements are performed within the kinematic acceptance of the selection and compared with the expectation from the Standard Model process e+e- -> nu nu gamma gamma(gamma). No evidence for new physics contributions to this final state is observed. Upper limits on sigma (e+e- -> XX) BR^2(X -> Ygamma) are derived for the case of stable and invisible Y. In the case of massive Y the combined limits obtained from all the data range from 10 fb to 60 fb, while for the special case of massless Y the range is 20 fb to 40 fb. The limits apply to pair production of excited neutrions (X=nu^*,Y=nu), to neutralino production (X=~chi^0_2, Y=~chi^0_1) and to supersymmetric models in which X=~chi^0_1 and Y=~G is a light gravitino.

  16. Measurement of the mass and width of the W boson in e+e- collisions at sqrt{s} = 161-209 GeV

    Science.gov (United States)

    Abdallah, J.; Abreu, P.; Adam, W.; Adzic, P.; Albrecht, T.; Alemany-Fernandez, R.; Allmendinger, T.; Allport, P. P.; Amaldi, U.; Amapane, N.; Amato, S.; Anashkin, E.; Andreazza, A.; Andringa, S.; Anjos, N.; Antilogus, P.; Apel, W.-D.; Arnoud, Y.; Ask, S.; Asman, B.; Augustin, J. E.; Augustinus, A.; Baillon, P.; Ballestrero, A.; Bambade, P.; Barbier, R.; Bardin, D.; Barker, G. J.; Baroncelli, A.; Battaglia, M.; Baubillier, M.; Becks, K.-H.; Begalli, M.; Behrmann, A.; Ben-Haim, E.; Benekos, N.; Benvenuti, A.; Berat, C.; Berggren, M.; Bertrand, D.; Besancon, M.; Besson, N.; Bloch, D.; Blom, M.; Bluj, M.; Bonesini, M.; Boonekamp, M.; Booth, P. S. L.; Borisov, G.; Botner, O.; Bouquet, B.; Bowcock, T. J. V.; Boyko, I.; Bracko, M.; Brenner, R.; Brodet, E.; Bruckman, P.; Brunet, J. M.; Buschbeck, B.; Buschmann, P.; Calvi, M.; Camporesi, T.; Canale, V.; Carena, F.; Castro, N.; Cavallo, F.; Chapkin, M.; Charpentier, Ph.; Checchia, P.; Chierici, R.; Chliapnikov, P.; Chudoba, J.; Chung, S. U.; Cieslik, K.; Collins, P.; Contri, R.; Cosme, G.; Cossutti, F.; Costa, M. J.; Crennell, D.; Cuevas, J.; D'Hondt, J.; da Silva, T.; da Silva, W.; Della Ricca, G.; de Angelis, A.; de Boer, W.; de Clercq, C.; de Lotto, B.; de Maria, N.; de Min, A.; de Paula, L.; di Ciaccio, L.; di Simone, A.; Doroba, K.; Drees, J.; Duperrin, A.; Eigen, G.; Ekelof, T.; Ellert, M.; Elsing, M.; Espirito Santo, M. C.; Fanourakis, G.; Fassouliotis, D.; Feindt, M.; Fernandez, J.; Ferrer, A.; Ferro, F.; Flagmeyer, U.; Foeth, H.; Fokitis, E.; Fulda-Quenzer, F.; Fuster, J.; Gandelman, M.; Garcia, C.; Gavillet, Ph.; Gazis, E.; Gokieli, R.; Golob, B.; Gomez-Ceballos, G.; Goncalves, P.; Graziani, E.; Grosdidier, G.; Grzelak, K.; Guy, J.; Haag, C.; Hallgren, A.; Hamacher, K.; Hamilton, K.; Haug, S.; Hauler, F.; Hedberg, V.; Hennecke, M.; Hoffman, J.; Holmgren, S.-O.; Holt, P. J.; Houlden, M. A.; Jackson, J. N.; Jarlskog, G.; Jarry, P.; Jeans, D.; Johansson, E. K.; Jonsson, P.; Joram, C.; Jungermann, L.; Kapusta, F.; Katsanevas, S.; Katsoufis, E.; Kernel, G.; Kersevan, B. P.; Kerzel, U.; King, B. T.; Kjaer, N. J.; Kluit, P.; Kokkinias, P.; Kourkoumelis, C.; Kouznetsov, O.; Krumstein, Z.; Kucharczyk, M.; Lamsa, J.; Leder, G.; Ledroit, F.; Leinonen, L.; Leitner, R.; Lemonne, J.; Lepeltier, V.; Lesiak, T.; Liebig, W.; Liko, D.; Lipniacka, A.; Lopes, J. H.; Lopez, J. M.; Loukas, D.; Lutz, P.; Lyons, L.; MacNaughton, J.; Malek, A.; Maltezos, S.; Mandl, F.; Marco, J.; Marco, R.; Marechal, B.; Margoni, M.; Marin, J.-C.; Mariotti, C.; Markou, A.; Martinez-Rivero, C.; Masik, J.; Mastroyiannopoulos, N.; Matorras, F.; Matteuzzi, C.; Mazzucato, F.; Mazzucato, M.; Mc Nulty, R.; Meroni, C.; Migliore, E.; Mitaroff, W.; Mjoernmark, U.; Moa, T.; Moch, M.; Moenig, K.; Monge, R.; Montenegro, J.; Moraes, D.; Moreno, S.; Morettini, P.; Mueller, U.; Muenich, K.; Mulders, M.; Mundim, L.; Murray, W.; Muryn, B.; Myatt, G.; Myklebust, T.; Nassiakou, M.; Navarria, F.; Nawrocki, K.; Nicolaidou, R.; Nikolenko, M.; Oblakowska-Mucha, A.; Obraztsov, V.; Olshevski, A.; Onofre, A.; Orava, R.; Osterberg, K.; Ouraou, A.; Oyanguren, A.; Paganoni, M.; Paiano, S.; Palacios, J. P.; Palka, H.; Papadopoulou, Th. D.; Pape, L.; Parkes, C.; Parodi, F.; Parzefall, U.; Passeri, A.; Passon, O.; Peralta, L.; Perepelitsa, V.; Perrotta, A.; Petrolini, A.; Piedra, J.; Pieri, L.; Pierre, F.; Pimenta, M.; Piotto, E.; Podobnik, T.; Poireau, V.; Pol, M. E.; Polok, G.; Pozdniakov, V.; Pukhaeva, N.; Pullia, A.; Radojicic, D.; Rames, J.; Read, A.; Rebecchi, P.; Rehn, J.; Reid, D.; Reinhardt, R.; Renton, P.; Richard, F.; Ridky, J.; Rivero, M.; Rodriguez, D.; Romero, A.; Ronchese, P.; Roudeau, P.; Rovelli, T.; Ruhlmann-Kleider, V.; Ryabtchikov, D.; Sadovsky, A.; Salmi, L.; Salt, J.; Sander, C.; Savoy-Navarro, A.; Schwickerath, U.; Sekulin, R.; Siebel, M.; Simard, L.; Sisakian, A.; Smadja, G.; Smirnova, O.; Sokolov, A.; Sopczak, A.; Sosnowski, R.; Spassov, T.; Stanitzki, M.; Stocchi, A.; Strauss, J.; Stugu, B.; Szczekowski, M.; Szeptycka, M.; Szumlak, T.; Tabarelli, T.; Tegenfeldt, F.; Thomas, J.; Timmermans, J.; Tkatchev, L.; Tobin, M.; Todorovova, S.; Tome, B.; Tonazzo, A.; Tortosa, P.; Travnicek, P.; Treille, D.; Tristram, G.; Trochimczuk, M.; Troncon, C.; Turluer, M.-L.; Tyapkin, I. A.; Tyapkin, P.; Tzamarias, S.; Uvarov, V.; Valenti, G.; van Dam, P.; van Eldik, J.; van Remortel, N.; van Vulpen, I.; Vegni, G.; Veloso, F.; Venus, W.; Verdier, P.; Verzi, V.; Vilanova, D.; Vitale, L.; Vrba, V.; Wahlen, H.; Washbrook, A. J.; Weiser, C.; Wicke, D.; Wickens, J.; Wilkinson, G.; Winter, M.; Witek, M.; Yushchenko, O.; Zalewska, A.; Zalewski, P.; Zavrtanik, D.; Zhuravlov, V.; Zimin, N. I.; Zintchenko, A.; Zupan, M.

    2008-05-01

    A measurement of the W boson mass and width has been performed by the DELPHI collaboration using the data collected during the full LEP2 programme (1996-2000). The data sample has an integrated luminosity of 660 pb-1 and was collected over a range of centre-of-mass energies from 161 to 209 GeV. Results are obtained by applying the method of direct reconstruction of the mass of the W from its decay products in both the W+W-→ℓν¯ℓqq¯’ and W+W-→qq¯’q¯q’ channels. The W mass result for the combined data set is M_W = 80.336 ±0.055 ({text{Stat.}}) ±0.028 ({text{Syst.}}) ±0.025 ({text{FSI}}) ±0.009 ({text{LEP}}) text{GeV}/c^2, where FSI represents the uncertainty due to final state interaction effects in the qq¯’q¯q’ channel, and LEP represents that arising from the knowledge of the collision energy of the accelerator. The combined value for the W width is {ΓW} = 2.404 ±0.140 ({text{Stat.}}) ±0.077 ({text{Syst.}}) ±0.065 ({text{FSI}}) text{GeV}/c^2. These results supersede all values previously published by the DELPHI collaboration.

  17. Excitation functions of residual nuclei production from 40–2600 MeV proton-irradiated 206,207,208,natPb and 209Bi

    Indian Academy of Sciences (India)

    Yu E Titarenko; V F Batyaev; V M Zhivun; V O Kudryashov; K A Lipatov; A V Ignatyuk; S G Mashnik

    2007-02-01

    The work is aimed at experimental determination of the independent and cumulative yields of radioactive residual nuclei produced in intermediate-energy proton-irradiated thin targets made of highly isotopic enriched and natural lead (206,207,208,natPb) and 209Bi. 5972 radioactive product nuclide yields have been measured in 55 thin targets induced by 0.04, 0.07, 0.10, 0.15, 0.25, 0.6, 0.8, 1.2, 1.4, 1.6 and 2.6 GeV protons extracted from the ITEP U-10 proton synchrotron. The measured data have been compared with data obtained at other laboratories as well as with theoretical simulations by seven codes. We found that the predictive power of the tested codes is different but is satisfactory for most of the nuclides in the spallation region, though none of the codes agree well with the data in the whole mass region of product nuclides and all should be improved further.

  18. Spontaneous deletion of a 209-kilobase-pair fragment from the Escherichia coli genome occurs with acquisition of resistance to an assortment of infectious phages.

    Science.gov (United States)

    Tanji, Yasunori; Hattori, Kenji; Suzuki, Kohichi; Miyanaga, Kazuhiko

    2008-07-01

    To breed resistance to an assortment of infectious phages, continuous cultures of Escherichia coli JM109 grown in a chemostat were exposed to phage mixtures prepared from sewage influent. Four sequential chemostat-grown cultures were each infected with a different phage mixture. At the end of a chemostat run, one phage-resistant colony was isolated and used to inoculate the subsequent culture. This process was repeated, and increased phage resistance of the input bacterial strain resulted from the successive challenges with different phage cocktails. Multiple mutations apparently accumulated progressively. A mutant isolated at the end of the four runs, designated D198, showed resistance to 38 of 40 phages that infect the parent strain, JM109. D198 produced less outer membrane protein C (OmpC) than JM109. However, restoration of the OmpC protein by plasmid-mediated complementation did not completely restore the susceptibility of D198 to the 38 phages. Therefore, alterations beyond the level of OmpC protein production contribute to the phage resistance of D198. PCR-based genetic analysis revealed that D198 has a genome that is 209 kbp (about 200 genes) smaller than JM109. The deletion includes the chromosomal section from ompC to wbbL that encodes the rhamnosyl transferase involved in lipopolysaccharide biosynthesis. Strains D198 and JM109 were comparable in their growth characteristics and their abilities to express a recombinant protein.

  19. Measurement of the Mass and Width of the W Boson in $e^{+}e^{-}$ Collisions at $\\sqrt{s}$ = 161 - 209 GeV

    CERN Document Server

    Abdallah, J; Adam, W; Adzic, P; Albrecht, T; Alemany-Fernandez, R; Allmendinger, T; Allport, P P; Amaldi, Ugo; Amapane, N; Amato, S; Anashkin, E; Andreazza, A; Andringa, S; Anjos, N; Antilogus, P; Apel, W D; Arnoud, Y; Ask, S; Åsman, B; Augustin, J E; Augustinus, A; Baillon, P; Ballestrero, A; Bambade, P; Barbier, R; Bardin, D; Barker, G J; Baroncelli, A; Battaglia, M; Baubillier, M; Becks, K H; Begalli, M; Behrmann, A; Ben-Haim, E; Benekos, N; Benvenuti, A; Bérat, C; Berggren, M; Bertrand, D; Besançon, M; Besson, N; Bloch, D; Blom, M; Bluj, M; Bonesini, M; Boonekamp, M; Booth, P S L; Borisov, G; Botner, O; Bouquet, B; Bowcock, T J V; Boyko, I; Bracko, M; Brenner, R; Brodet, E; Brückman, P; Brunet, J M; Buschbeck, B; Buschmann, P; Calvi, M; Camporesi, T; Canale, V; Carena, F; Castro, N; Cavallo, F; Chapkin, M; Charpentier, P; Checchia, P; Chierici, R; Chliapnikov, P V; Chudoba, J; Chung, S U; Cieslik, K; Collins, P; Contri, R; Cosme, G; Cossutti, F; Costa, M J; Crennell, D J; Cuevas-Maestro, J; D'Hondt, J; Da Silva, T; Da Silva, W; Della Ricca, G; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Maria, N; De Min, A; De Paula, L; Di Ciaccio, L; Di Simone, A; Doroba, K; Drees, J; Duperrin, A; Eigen, G; Ekelöf, T J C; Ellert, M; Elsing, M; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Feindt, M; Fernández, J; Ferrer, A; Ferro, F; Flagmeyer, U; Föth, H; Fokitis, E; Fulda-Quenzer, F; Fuster, J; Gandelman, M; García, C; Gavillet, P; Gazis, E; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; Graziani, E; Grosdidier, G; Grzelak, K; Guy, J; Haag, C; Hallgren, A; Hamacher, K; Hamilton, K; Haug, S; Hauler, F; Hedberg, V; Hennecke, M; Hoffman, J; Holmgren, S O; Holt, P J; Houlden, M A; Jackson, J N; Jarlskog, G; Jarry, P; Jeans, D; Johansson, E K; Jonsson, P; Joram, C; Jungermann, L; Kapusta, F; Katsanevas, S; Kokkinias, P; Leinonen, L; Katsoufis, E; Kernel, G; Kersevan, B P; Krumshtein, Z; Lesiak, T; Kerzel, U; Liebig, W; King, B T; Lamsa, J; Liko, D; Kjaer, N J; Leder, G; Kluit, P; Kourkoumelis, C; Leitner, R; Kuznetsov, O; Kucharczyk, M; Ledroit, F; Lopes, J H; Lemonne, J; Lepeltier, V; Lipniacka, A; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Malek, A; Maltezos, S; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J C; Mariotti, C; Markou, A; Martínez-Rivero, C; Masik, J; Mastroyiannopoulos, N; Matorras, F; Matteuzzi, C; Mazzucato, F; Mazzucato, M; McNulty, R; Meroni, C; Migliore, E; Mitaroff, W A; Mjörnmark, U; Moa, T; Moch, M; Mönig, K; Monge, R; Montenegro, J; Moraes, D; Moreno, S; Morettini, P; Müller, U; Münich, K; Mulders, M; Mundim, L; Murray, W; Muryn, B; Myatt, G; Myklebust, T; Paganoni, M; Nassiakou, M; Paiano, S; Navarria, F; Nawrocki, K; Nicolaidou, R; Nikolenko, M; Ouraou, A; Parkes, C; Oblakowska-Mucha, A; Oyanguren, A; Obraztsov, V F; Olshevski, A; Palacios, J P; Onofre, A; Palka, H; Orava, R; Österberg, K; Pape, L; Papadopoulou, T D; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Peralta, L; Perepelitsa, V; Perrotta, A; Petrolini, A; Piedra, J; Pieri, L; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Poireau, V; Pol, M E; Polok, G; Pozdnyakov, V; Pukhaeva, N; Pullia, A; Radojicic, D; Rames, J; Read, A; Rebecchi, P; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Richard, F; Rídky, J; Rivero, M; Rodríguez, D; Romero, A; Ronchese, P; Roudeau, P; Rovelli, T; Ruhlmann-Kleider, V; Ryabtchikov, D; Sadovskii, A; Salmi, L; Salt, J; Sander, C; Savoy-Navarro, A; Schwickerath, U; Sopczak, A; Szeptycka, M; Sekulin, R; Siebel, M; Spassoff, Tz; Tabarelli de Fatis, T; Simard, L; Stanitzki, M; Tegenfeldt, F; Sisakian, A; Stocchi, A; Thomas, J; Smadja, G; Strauss, J; Smirnova, O; Stugu, B; Sokolov, A; Sosnowski, R; Szumlak, T; Szczekowski, M; Tkatchev, L; Tobin, M; Timmermans, J; Todorovova, S; Tomé, B; Tonazzo, A; Tortosa, P; Travnicek, P; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M L; Tyapkin, I A; Tyapkin, P; Tzamarias, S; Uvarov, V; Valenti, G; van Dam, P; Van Eldik, J; Vilanova, D; Winter, M; Van Remortel, N; Vitale, L; Witek, M; Vrba, V; Van Vulpen, I; Wahlen, H; Vegni, G; Veloso, F; Weiser, C; Venus, W; Wicke, D; Verdier, P; Verzi, V; Washbrook, A J; Wickens, J; Wilkinson, G; Zimin, N I; Yushchenko, O; Zalewska-Bak, A; Zalewski, P; Zavrtanik, D; Zhuravlov, V; Zintchenko, A; Zupan, M

    2008-01-01

    A measurement of the W boson mass and width has been performed by the DELPHI collaboration using the data collected during the full LEP2 programme (1996-2000). The data sample has an integrated luminosity of 660 pb^-1 and was collected over a range of centre-of-mass energies from 161 to 209 GeV. Results are obtained by applying the method of direct reconstruction of the mass of the W from its decay products in both the W+W- -> lvqq and W+W- -> qqqq channels. The W mass result for the combined data set is M_W = 80.336 +/- 0.055 (Stat.) +/- 0.028 (Syst.) +/- 0.025 (FSI) +/- 0.009 (LEP) GeV/c^2, where FSI represents the uncertainty due to final state interaction effects in the qqqq channel, and LEP represents that arising from the knowledge of the collision energy of the accelerator. The combined value for the W width is Gamma_W = 2.404 +/- 0.140 (Stat.) +/- 0.077 (Syst.) +/- 0.065 (FSI) GeV/c^2. These results supersede all values previously published by the DELPHI collaboration. This paper is dedicated to the m...

  20. Modes of transference and rupture of the nucleus with neutron halos 6 He on 209 Bi near of the Coulomb barrier

    International Nuclear Information System (INIS)

    In recent experiments, the fusion of the exotic radioactive nucleus 6 He with 209 Bi has been studied for the first time at energies above and below the Coulomb barrier. A considerable enhancement in the fusion was observed, which implies a reduction of about 25% in the nominal fusion barrier. Some previous theoretical works suggest that this striking effect may be caused by the coupling to neutron transfer channels with a positive Q-value which would lead to a neutron flow and the consequent formation of a neck between the projectile and the target. Later, in the current work, we ran two new experiments on the same reaction using the FN Tandem Van de Graaff (10 MV) accelerator and the dual superconducting TwinSol system, both of them belonging to the University of Notre Dame, USA. This time, the purpose was to study one- and two-neutron transfer and the 6 He projectile breakup at laboratory energies of 14.7, 16.2, 17.9, 19.0 and 22.5 MeV. A strong group of 4 He was observed (with an effective Q-value about .5 MeV) whose integrated cross section results exceptionally high, exceeding the fusion cross section both above and below the barrier. The simultaneously measured elastic scattering angular distribution required high total cross sections so that this yield is confirmed. Preliminary coupled channels calculations sing the computer program called Fresco developed at the University of Surrey (England) suggested that the reaction mechanisms may be better described as a direct nuclear breakup and two-neutron transfer to unbound states in 211 Bi. These calculations predicted also an enhancement in the fusion cross section below the barrier due to the transfer and breakup channel coupling, which strongly suggests that this channel is the 'doorway state' that explains the fusion barrier reduction observed in previous experiments. It was found that the 4 He group fully dominates the total reaction cross section at the measured energies and we show evidence that a new

  1. Analysis of type 2 diabetes patients with ABI and CAVI%209例Ⅱ型糖尿病患者ABI和CAVI测定结果分析

    Institute of Scientific and Technical Information of China (English)

    任明容; 张勇

    2012-01-01

    目的 N探讨Ⅱ型糖尿病患者踝臂指数(ankle-brachial index,ABI)与心踝血管指数(cardio-ankle vascular index,CAVI)对早期糖尿病大血管病变监测的临床意义.方法 随机选取Ⅱ型糖尿病患者209例,测定ABI与CAVI值.结果 右侧ABI:89例(42.6%)在正常范围,76例(36.1%)有动脉闭塞可能,42例(20.1%)动脉闭塞可能性较高,2例(1.0%)血管有早期动脉硬化或有钙化现象;左侧ABI:94例(44.9%)在正常值范围,72例(34.4%)有动脉闭塞的可能,38例(18.2%)动脉闭塞的可能性较高,5例(2.5%)血管有早期动脉硬化或钙化现象.右侧CAVI:136例(65.1%)在正常范围,62例(29.6%)有动脉闭塞可能,11例(5.2%)动脉闭塞可能性较高;左侧CAVI:146例(69.8%)在正常范围,58例(27.8%)有动脉闭塞可能,5例(2.4%)动脉闭塞可能性较高.结论 在Ⅱ型糖尿病患者中应用ABI和CAVI测定,有利于筛选出合并大血管病变患者,具有临床应用意义.%Objective To explore the type 2 diabetic patients with ankle brachial index ( ankle-brachial, index, ABI ) and cardio-ankle vascular index ( cardio-ankle vascular index,CAVI ) on early stage of diabetic macrovascular disease and the clinical significance of monitoring. Methods We randomly selected patients with type 209 diabetes mellitus patients to determinate the value of ABI and CAVI. Results Right ABI:89 cases ( 42. 6% ] were in the normal range;in 76 cases ( 36.1%) with arterial occlusion may;in 42 cases ( 20. 1%) arterial occlusion higher likelihood;in 2 cases [1% ) vascular early arteriosclerosis or calcification phenomenon. The left ABI:94 cases ( 44. 9%) in the range of normal value; in 72 cases ( 34.4%) with arterial occlusion may; 38 (18.2%) ABI artery occlusion with the possibility of higher; in 5 cases (2. 5 %) vascular early arteriosclerosis or calcification phenomenon. Right CAVI: 136 cases (65.1 %) were in the normal range; in 62 cases ( 29. 6%) with arterial occlusion may;in 11

  2. Evaluation of the toxic effects of brominated compounds (BDE-47, 99, 209, TBBPA) and bisphenol A (BPA) using a zebrafish liver cell line, ZFL

    International Nuclear Information System (INIS)

    Highlights: • A homologous zebrafish thyroid hormone (TH) receptor (TR) reporter gene system was developed in a zebrafish liver cell-line (ZFL) to study the possible effects of chemicals on TR activities. • BPA was found to have antagonistic effects on T3 induced TR activity, BDE-47, BDE-99, and TBBPA did not show any interference of TR activity. • Down regulation of deiodinases and some sulfation enzymes or phase II enzymes by the tested chemicals indicated their impacts on TH eleiminations. • The up-regulation of tranthyretin by BDE-47 at 96 h long-term exposure gave a link to the CYP family for its role in producing a more toxic and oxidized form. - Abstract: The toxic effects of three polybrominated diphenyl ether (PBDE) congeners (BDE-47, -99, and -209), tetrabromobisphenol A (TBBPA) and bisphenol A (BPA), were evaluated by determining their 24 h and 96 h median lethal concentrations using a zebrafish liver cell line, ZFL. It was found that BDE-47, BDE-99 and TBBPA showed comparative cytotoxicity within the range of 1.2–4.2 μM, and were more toxic than BPA (367.1 μM at 24 h and 357.6 μM at 96 h). However, BDE-209 induced only 15% lethality with exposures up to 25 μM. The molecular stresses of BDE-47, -99, TBBPA and BPA involved in thyroid hormone (TH) homeostasis and hepatic metabolism were also investigated. Using a reporter gene system to detect zebrafish thyroid hormone receptor β (zfTRβ) transcriptional activity, the median effective concentration of triiodothyronine (T3) was determined to be 9.2 × 10−11 M. BDE-47, BDE-99, TBBPA and BPA alone, however, did not exhibit zfTRβ agonistic activity. BPA displayed T3 (0.1 nM) induced zfTRβ antagonistic activity with a median inhibitory concentration of 19.3 μM. BDE-47, BDE-99 and TBBPA displayed no antagonistic effects of T3-induced zfTRβ activity. Target gene expressions were also examined under acute exposures. The significant inhibition of different types of deiodinases by all of the

  3. Evaluation of the toxic effects of brominated compounds (BDE-47, 99, 209, TBBPA) and bisphenol A (BPA) using a zebrafish liver cell line, ZFL

    Energy Technology Data Exchange (ETDEWEB)

    Yang, Jie; Chan, King Ming, E-mail: kingchan@cuhk.edu.hk

    2015-02-15

    Highlights: • A homologous zebrafish thyroid hormone (TH) receptor (TR) reporter gene system was developed in a zebrafish liver cell-line (ZFL) to study the possible effects of chemicals on TR activities. • BPA was found to have antagonistic effects on T3 induced TR activity, BDE-47, BDE-99, and TBBPA did not show any interference of TR activity. • Down regulation of deiodinases and some sulfation enzymes or phase II enzymes by the tested chemicals indicated their impacts on TH eleiminations. • The up-regulation of tranthyretin by BDE-47 at 96 h long-term exposure gave a link to the CYP family for its role in producing a more toxic and oxidized form. - Abstract: The toxic effects of three polybrominated diphenyl ether (PBDE) congeners (BDE-47, -99, and -209), tetrabromobisphenol A (TBBPA) and bisphenol A (BPA), were evaluated by determining their 24 h and 96 h median lethal concentrations using a zebrafish liver cell line, ZFL. It was found that BDE-47, BDE-99 and TBBPA showed comparative cytotoxicity within the range of 1.2–4.2 μM, and were more toxic than BPA (367.1 μM at 24 h and 357.6 μM at 96 h). However, BDE-209 induced only 15% lethality with exposures up to 25 μM. The molecular stresses of BDE-47, -99, TBBPA and BPA involved in thyroid hormone (TH) homeostasis and hepatic metabolism were also investigated. Using a reporter gene system to detect zebrafish thyroid hormone receptor β (zfTRβ) transcriptional activity, the median effective concentration of triiodothyronine (T3) was determined to be 9.2 × 10{sup −11} M. BDE-47, BDE-99, TBBPA and BPA alone, however, did not exhibit zfTRβ agonistic activity. BPA displayed T3 (0.1 nM) induced zfTRβ antagonistic activity with a median inhibitory concentration of 19.3 μM. BDE-47, BDE-99 and TBBPA displayed no antagonistic effects of T3-induced zfTRβ activity. Target gene expressions were also examined under acute exposures. The significant inhibition of different types of deiodinases by all of

  4. 20.9.Extrapyramidal disorder

    Institute of Scientific and Technical Information of China (English)

    1992-01-01

    920191 Effect of 6-hydroxydopamine oncerebral catecholamines,lipid peroxidationand antioxidant enzymes in rat-concernedwith pathogensis of Parkinson’s disease.LIANG Liping (梁立平),JIANG Dehua (江德华).Dept Neurol,Neurolgic Instit,Tianjing,300052.Chin J Neurol and Psychiat 1991; 24 (4): 223-227.As an animal model of human Parkinson’s

  5. 十溴联苯醚降解菌群的降解特性与组成分析%Characteristics and composition of the microbial consortium for decabromodiphenyl ether (BDE-209) degradation

    Institute of Scientific and Technical Information of China (English)

    陈桂兰; 陈杏娟; 郭俊; 孙国萍; 陆祖军; 麦碧娴; 许玫英

    2013-01-01

    [Objective] A microbial consortium Cf3, which was obtained and enriched from an e-waste contaminated river sediment, was applied to study the characteristics for decabromodiphenyl ether (BDE-209) degradation in order to pave a way for the bioremediation of PBDEs contaminant in sediment. And the composition of the microbial consortium was also studied. [Methods] Congeners of BDE-209 after the biodegradation were analyzed by GC-MS and the degradation rates were calculated. The composition of the microbial consortium was analyzed by DGGE. [Results] High BDE-209 degradation rates were obtained by consortium Cf3. After 120 days incubation, 80.03% BDE-209 was transformed by consortium Cf3 when the initial amount of BDE-209 was 2.6 μmol. Meanwhile, the biomass was obtained and the OD600 value increased from 0.01 to 0.21. The pH also changed from 6.93 to 8.50 during the degradation process. Ten cultivable strains were isolated from this consortium, six of which associated with Citrobacter spp. and four with Alcaligenes spp. based on the 16S rRNA gene sequences. Denaturing gradient gel electrophoresis (DGGE) results showed that other four major genera Wolinella spp., Acidaminococcus spp., Acetobacterium spp. and Desulfovibrio spp. were presented besides Citrobacter spp. and Alcaligenes spp.. However, the bands for Acetobacterium spp. and Desulfovibrio spp. disappeared with prolonging the incubation time. [Conclusion] A microbial consortium with high PBDEs degradation rate was obtained. The data obtained in the study about the characteristics of the degradation of BDE-209 by the microbial consortium and the composition of the consortium could provides some useful information and precious strains resources for the anaerobic bioremediation of polybrominated di-phenyl ethers (PBDEs) in the persistent organic polluted environment.%[目的]针对水体沉积物中日益严重的多溴联苯醚污染问题,以电子垃圾污染河床沉积物为种源

  6. Polychlorinated biphenyl (PCB) concentrations and congener composition in masu salmon from Japan: A study of all 209 PCB congeners by high-resolution gas chromatography/high-resolution mass spectrometry (HRGC/HRMS)

    International Nuclear Information System (INIS)

    Highlights: • Two subspecies of masu salmon collected from central to northern Japan were examined. • All 209 PCB congeners in the fish were analyzed by HRGC/HRMS with δ15N and δ13C determinations. • ∑ PCBs was highest in fish that had upstreamed from Ise Bay, which is close to a heavy industrial area. • However, TEQdl-PCBs values were highest in fish from southern part of the Sea of Japan. - Abstract: We collected two subspecies of masu salmon: Oncorhynchus masou masou from four localities (southern Sea of Japan northward to Hokkaido) and O. masou ishikawae from upstream from Ise Bay close to a heavy industrial area. All 209 PCB congeners were analyzed using HRGC/HRMS. PCA ordination of congener concentrations divided data into three groups: (i) ssp. masou from Hokkaido, (ii) ssp. masou from the other regions and (iii) ssp. ishikawae. The highest ∑ PCB concentration (40.39 ng/wet wt) was in ssp. ishikawae followed by ssp. masou from southern waters; however the TEQdioxin-like PCBs was highest in ssp. masou from southern water (1.96 pg-TEQdioxin-like PCBs/g wet wt.) due to the high proportion of congener #126 in its complement (#126 has the highest toxic equivalency factor among congeners). There is likely a contamination source offshore in the southern Sea of Japan and/or along the migratory route of ssp. masou

  7. Modes of transference and rupture of the nucleus with neutron halos {sup 6} He on {sup 209} Bi near of the Coulomb barrier; Modos de transferencia y rompimiento del nucleo con halo neutronico {sup 6} He sobre {sup 209} Bi cerca de la barrera de Coulomb

    Energy Technology Data Exchange (ETDEWEB)

    Lizcano C, D

    2003-07-01

    In recent experiments, the fusion of the exotic radioactive nucleus {sup 6} He with {sup 209} Bi has been studied for the first time at energies above and below the Coulomb barrier. A considerable enhancement in the fusion was observed, which implies a reduction of about 25% in the nominal fusion barrier. Some previous theoretical works suggest that this striking effect may be caused by the coupling to neutron transfer channels with a positive Q-value which would lead to a neutron flow and the consequent formation of a neck between the projectile and the target. Later, in the current work, we ran two new experiments on the same reaction using the FN Tandem Van de Graaff (10 MV) accelerator and the dual superconducting TwinSol system, both of them belonging to the University of Notre Dame, USA. This time, the purpose was to study one- and two-neutron transfer and the {sup 6} He projectile breakup at laboratory energies of 14.7, 16.2, 17.9, 19.0 and 22.5 MeV. A strong group of {sup 4} He was observed (with an effective Q-value about .5 MeV) whose integrated cross section results exceptionally high, exceeding the fusion cross section both above and below the barrier. The simultaneously measured elastic scattering angular distribution required high total cross sections so that this yield is confirmed. Preliminary coupled channels calculations sing the computer program called Fresco developed at the University of Surrey (England) suggested that the reaction mechanisms may be better described as a direct nuclear breakup and two-neutron transfer to unbound states in {sup 211} Bi. These calculations predicted also an enhancement in the fusion cross section below the barrier due to the transfer and breakup channel coupling, which strongly suggests that this channel is the 'doorway state' that explains the fusion barrier reduction observed in previous experiments. It was found that the {sup 4} He group fully dominates the total reaction cross section at the

  8. β-Thalassemia major resulting from compound heterozygosity for HBB: c.92+2T>C [formerly known as IVS-I-2 (T>C)] and a novel β(0)-thalassemia frameshift mutation: HBB: c.209delG; p.Gly70Valfs*20.

    Science.gov (United States)

    Kluge, Michelle L; Hoyer, James D; Swanson, Kenneth C; Oliveira, Jennifer L

    2014-01-01

    A novel β(0)-thalassemia (β-thal) frameshift mutation, HBB: c.209delG; p.Gly70Valfs*20, is described in a 21-year-old African American female with β-thalassemia major (β-TM) due to compound heterozygosity for the β(0)-thal mutation HBB: c.92+2T>C [formerly known as IVS-I-2 (T>C)] and HBB: c.209delG. The combination of these mutations demonstrates a complete lack of β-globin chain synthesis, evidenced by the proband having no Hb A present.

  9. Production cross section of At radionuclides from $^{7}$Li+$^{\\textrm{nat}}$Pb and $^{9}$Be+$^{\\textrm{nat}}$Tl reactions

    CERN Document Server

    Maiti, Moumita

    2011-01-01

    Earlier we reported theoretical studies on the probable production of astatine radionuclides from $^{6,7}$Li and $^{9}$Be-induced reactions on natural lead and thalliun targets, respectively. For the first time, in this report, production of astatine radionuclides has been investigated experimentally with two heavy ion induced reactions: $^{9}$Be+$^{\\textrm{nat}}$Tl and $^{7}$Li+$^{\\textrm{nat}}$Pb. Formation cross sections of the evaporation residues, $^{207,208,209,210}$At, produced in (HI, xn) channel, have been measured by the stacked-foil technique followed by the off-line $\\gamma$-spectrometry at the low incident energies ($<$50 MeV). Measured excitation functions have been explained in terms of compound nuclear reaction mechanism using Weisskopf-Ewing and Hauser-Feshbach model. Absolute cross section values are lower than the respective theoretical predictions.

  10. Measurements of delayed neutrons yields and time spectra from 1 GeV protons interacting with thick {sup nat}Pb, {sup 209}Bi and {sup nat}Fe targets

    Energy Technology Data Exchange (ETDEWEB)

    Ridikas, D.; Blideanu, V.; David, J.C.; Dore, D.; Prevost, A. [CEA Saclay, Dept. d' Astrophysique, de Physique des Particules de Physique Nucleaire et de l' Instrumentation Associee, 91- Gif sur Yvette (France); Ledoux, X. [CEA Bruyeres-le-Chatel (CEA/DIF, DPTA/SPN), 91 (France); Barzakh, A.; Fedorov, D.; Moroz, F.; Panteleev, V.; Shcherbakov, O.; Vorobyev, A. [Petersburg Nuclear Physics Institute, Leningrad district (Russian Federation); Plukiene, R.; Plukis, A. [Institute of Physics, Vilnius (Lithuania)

    2008-07-01

    This paper presents the experimental results on the delayed neutrons (DN) yields and time spectra from 1 GeV protons interacting with natural lead, {sup 209}Bi and natural iron targets of variable thicknesses from 5 cm to 55 cm. Both absolute yields and time constants were obtained. In parallel, the MCNPX and PHITS codes were used to predict the DN precursors and construct the theoretical DN tables. Different model parameters are examined and show significant dependence on the choice of the intra-nuclear cascade and fission-evaporation models used. These data and modelling are of great importance for the new generation spallation neutron sources based on liquid metal technologies. Finally, the above experiment allowed the determination of the production cross sections of a number of delayed neutrons precursors as, {sup 87}Br, {sup 88}Br and {sup 17}N. For the 3 targets the emission of delayed neutrons is dominated by light reaction products such as {sup 9}Li and {sup 17}N during decay times from 0 to 20-30 s. In the case of fissile targets after longer decay times the fission fragments such as {sup 88}Br and {sup 87}Br are the major contributors. These results permit the examination of two different reaction mechanisms, namely fission and fragmentation, implemented in high energy transport codes. (authors)

  11. Eeffect of maternal BDE-209 on the cholinergic neurotransmitter system in the hippocampus of offspring rats%母源性十溴联苯醚暴露对仔鼠海马胆碱能神经递质系统的影响

    Institute of Scientific and Technical Information of China (English)

    吴英; 余艳红; 陈敦金

    2013-01-01

    目的:从胆碱能神经递质系统角度探讨母源性十溴联苯醚(BDE-209)损伤仔鼠神经系统的可能机制.方法:3 月龄wistar雌鼠自确定交配成功后随机分为实验组(A、B、C、D组)和对照组(E组),通过灌胃方法建立自妊娠期至哺乳期的不同剂量BDE-209[100、300、600、1 200 mg/(kg?d)]的暴露模型,21 d仔鼠断乳后各组随机选取10只仔鼠作为研究对象,应用免疫组织化学和比色法分别测定各组仔鼠海马组织中乙酰胆碱纤维(ACH)含量、乙酰胆碱酯酶(ACHE)活性、毒蕈碱受体(M.ACHR)含量、烟碱受体(N-ACHR)含量.结果:与E组相比,B、C、D组ACH含量和ACHE活性下降;C、D组M.ACHR含量下降;仅D组N-ACHR含量下降.结论:-定剂量的母源性BDE-209可能通过影响仔鼠胆碱能神经递质系统而具有神经毒性,且存在剂量效应关系.%Objective To study the possible mechanism of the damage of nerve system of prenatal induced by lactational BDE-209 (brominated Diphenyl Ethers-209) in the offspring rats from the cholinergic neurotransmitter system point of view. Methods After mating successfully, the female Wistar rats at the age of 3 months were divided into five groups randomly including the experimental group A, B, C, D and the control group E. BDE-209 was given in doses of 100(group A) , 300(group B) , 600(group C) , 1 200 (group D) mg/(kg·d) by oral gavage for maternal rats in the experimental groups. Ten rats of the first weaning offspring in each group were selected randomly. We determined the contents of acetylcholine, muscarinic cholinoreceptor, cholinergic nicotinic receptor and the activity of acetylcholinesterase by immunohistochemistry and chromatometry in each group. Results Compared with group E, the concentration of acetylcholine and the activity of acetylcholinesterase decreased significantly in group B , C and D, the concentration of muscarinic cholinoreceptor decreased significantly in group C and D , and the concentration

  12. Has Special Delisting System of China Achieved Policy Effect? ——Empirical Test from 209 Special Treatment Companies during 1998~2013 in China%中国特殊性退市制度达到政策性效果了吗?——基于中国1998~2013年209家ST上市公司的实证分析

    Institute of Scientific and Technical Information of China (English)

    贾天明; 雷良海

    2016-01-01

    The research is based on two angles, one is the volatility of the unsystematic risk for listed companies; the other one is the valuation for companies' share price. By sampling 209 A-share ST companies listed in Shanghai and Shenzhen from 1998 to 2013, we discuss the implementation consequence of the policy on ST thoroughly and meticu-lously. The results show that after the control of the fixed effects about the companies' characteristics, industry and time, the implementation of the ST is positively related with the unsystematic risk of listed companies, is negatively related with the stock value of companies. After introducing the earnings management variables that can reflect the behavior of companies' managers, earnings management activities have a weak effect on decreasing the unsystematic risk, on the contrary the earnings management activities increase ST policy effects in small increments on the unsystematic risk. Thus we conclude that ST policy plays a warning role, protects the rights and interests of investors, achieves a good policy effect. The investment decision-making behavior of investors in China has gradually inclined to be reasonable. The effect of traditional financial packaging methods is not increasingly obvious for investors.%本研究从上市公司非系统性风险和公司股票估值的角度出发,采用1998年至2013年具有时间连续性的209家ST上市企业为研究样本,对ST政策的实施效果进行了深入细致的探讨. 结果发现,在控制了公司特征、行业和时间固定效应后,ST政策的实施与上市公司非系统性风险呈正相关,与公司股票价值呈负相关;在引入反映公司管理者行为的盈余管理变量后,盈余管理并未起到降低企业非系统性风险的作用,相反却增加了ST政策对企业非系统性风险的影响效果. 基于上述分析,ST政策的实施起到了警示作用,保护了投资者的权益;我国投资者的投资决策行为逐渐趋向理性,影

  13. 10 CFR 209.3 - Definitions.

    Science.gov (United States)

    2010-01-01

    ... pursuant to the Agreement on an International Energy Program signed at Paris on November 18, 1974, including (1) the Annex entitled “Emergency Reserves”, (2) any amendment to such Agreement which includes another nation as a Party to such Agreement, and (3) any technical or clerical amendment to such...

  14. 33 CFR 136.209 - Proof.

    Science.gov (United States)

    2010-07-01

    ... claim. Final cost estimates for conducting damage assessments or implementing a restoration plan may form the basis for a claim against the Fund for an uncompensated natural resources damage claim. (c... a claim for the same natural resources damages and that payment of any subpart of the...

  15. 23 CFR 645.209 - General requirements.

    Science.gov (United States)

    2010-04-01

    ... this part and the provisions of 23 CFR 1.23(c) for longitudinal installations. (f) Direct Federal... enhancement and natural beauty. Such areas include public park and recreational lands, wildlife and waterfowl... standards set forth in the current edition of the “Manual on Uniform Traffic Control Devices” (MUTCD) and...

  16. 21 CFR 209.2 - Definitions.

    Science.gov (United States)

    2010-04-01

    .... Pharmacy includes, but is not limited to, a retail, mail order, Internet, hospital, university, or clinic pharmacy, or a public health agency, regularly and lawfully engaged in dispensing prescription drugs....

  17. Underground research laboratory room 209 instrument array

    International Nuclear Information System (INIS)

    An in situ excavation response test was conducted at the 240 level of the Underground Research Laboratory (URL). The test was carried out in conjunction with drill and blast excavation of a near-circular tunnel, about 3.5 m in diameter. The tunnel was excavated through a tunnel axis. Three modelling groups made predictions of the response of the rock mass and hydraulic behaviour of the water-bearing fracture to excavation. Two of the groups used the three-dimensional Finite-element Method and one group used the Discontinuous Deformation Analysis Method. Both methods predicted displacements and stress changes that agreed reasonably well with the measured response, but none of the methods predicted the hydraulic response of the fracture

  18. 48 CFR 209.403 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... determines that a contractor has engaged in bid-rigging, price-fixing, or other anti-competitive behavior; or... the Federal Property Management Regulations (41 CFR 101-45.6) and the Defense Materiel...

  19. 22 CFR 209.9 - Hearings.

    Science.gov (United States)

    2010-04-01

    ... thereof shall be conducted in conformity with 5 U.S.C. 554-557 (sections 5-8 of the Administrative... opportunity shall be given to refute facts and arguments advanced on either side of the issues. A...

  20. 22 CFR 1203.735-209 - Indebtedness.

    Science.gov (United States)

    2010-04-01

    ... Foreign Relations UNITED STATES INTERNATIONAL DEVELOPMENT COOPERATION AGENCY EMPLOYEE RESPONSIBILITIES AND... obligation means one acknowledged by the employee or reduced to judgement by a court or one imposed by law such as Federal, State, or local taxes, and “in a proper and timely manner” means in a manner which...

  1. 22 CFR 209.5 - Assurance required.

    Science.gov (United States)

    2010-04-01

    ... application for Federal financial assistance to an institution of higher education (including assistance for... financing construction of new or improvement of existing facilities on such property for the purposes for... necessary to accomplish such financing, and upon such conditions as he deems appropriate, to forbear...

  2. 49 CFR 209.3 - Definitions.

    Science.gov (United States)

    2010-10-01

    ... transferred by the DOT Act include, but are not limited to, the following statutes: (i) the Safety Appliance...); (ii) the Locomotive Inspection Act (49 U.S.C. 20102, 20701-20703, 21302, and 21304, formerly...

  3. 7 CFR 20.9 - Records.

    Science.gov (United States)

    2010-01-01

    ... lading or delivery documents evidencing all such exports and inspection and weight certificates relating thereto. Such records shall be available during regular business hours for inspection and audit...

  4. Evidence Based Education Request Desk. EBE #209

    Science.gov (United States)

    Regional Educational Laboratory Southeast, 2008

    2008-01-01

    What are states doing to improve graduation rates? A requester asked a state scan matrix of Southern Regional Education Board (SREB) states or other states with similar student demographics, and other states with exemplary programs with great successes. This paper responds to this request.

  5. Evaluation of a Wet Chemistry Method for Isolation of Cyclotron Produced [211At]Astatine

    Directory of Open Access Journals (Sweden)

    Shigeki Watanabe

    2013-09-01

    Full Text Available A “wet chemistry” approach for isolation of 211At from an irradiated bismuth target is described. The approach involves five steps: (1 dissolution of bismuth target in conc. HNO3; (2 removal of the HNO3 by distillation; (3 dissolution of residue in 8 M HCl; (4 extraction of 211At from 8 M HCl into DIPE; and (5 extraction of 211At from DIPE into NaOH. Results from 55 “optimized” 211At isolation runs gave recovery yields of approximately 78% after decay and attenuation corrections. An attenuation-corrected average of 26 ± 3 mCi in the target provided isolated (actual yields of 16 ± 3 mCi of 211At. A sixth step, used for purification of 211At from trace metals, was evaluated in seven runs. In those runs, isolated 211At was distilled under reductive conditions to provide an average 71 ± 8% recovery. RadioHPLC analyses of the isolated 211At solutions, both initial and after distillation, were obtained to examine the 211At species present. The primary species of 211At present was astatide, but astatate and unidentified species were also observed. Studies to determine the effect of bismuth attenuation on 211At were conducted to estimate an attenuation factor (~1.33 for adjustment of 211At readings in the bismuth target.

  6. Production of Astatine-211 at the Duke University Medical Center for its regional distribution

    Energy Technology Data Exchange (ETDEWEB)

    Zalutsky, Michael [Duke University Medical Center, Durham, NC (United States)

    2016-01-01

    Systemic targeted radiation therapy and radioimmunotherapy continue to be important tools in the treatment of certain cancers. Because of their high energy and short path length, alpha particle emitters such as 211At are more effective than either external beam x- ray or in vivo beta radiation in delivering potentially curative doses of radiation. The limited clinical trials that have been conducted to date have yielded encouraging responses in some patients, e.g., malignant brain tumors. In order to escalate the additional necessary research and development in radiochemistry, radiobiology and efficacy evaluation of alpha particle radiotherapeutics, it is universally agreed that access to an affordable, reliable supply of 211At is warranted. In conjunction with the Department of Energy's intent to enhance stable and radioactive isotope availability for research applications, it is the primary objective of this project to improve 211At production and purification capabilities at Duke so that this radionuclide can be supplied to researchers at other institutions throughout the US.The most widely used 211At production method involves the α,2n reaction on Bismuth using a cyclotron with beams ≤ 28 MeV. Yields can be enhanced with use of an internal target that allows for a higher alpha fluence plus efficient heat dissipation in the target. Both of these items are in place at Duke; however, in order to support production for multi-institutional use, irradiation campaigns in excess of 50 µAp and four hours duration will be needed. Further, post-irradiation processing equipment is lacking that will enable the distribution process. Financial support is sought for i) a shielded, ventilated processing/containment hood; ii) development of a post-irradiation target retrieval system; iii) fabrication of a 211At distillation and recovery module and iv) a performance review and, where needed, an enhancement of seven major subsystems that comprise the CS-30 Cyclotron. With these modifications in place, routine production of ≥200 mCi of At-211 should be readily achievable, given our methodological development of At-211 target preparation, internal target irradiation and dry distillation to recover the radionuclide.

  7. Final Report for grant entitled "Production of Astatine-211 for U.S. Investigators"

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, Daniel Scott

    2012-12-12

    Alpha-particle emitting radionuclides hold great promise in the therapy of cancer, but few alpha-emitters are available to investigators to evaluate. Of the alpha-emitters that have properties amenable for use in humans, 211At is of particular interest as it does not have alpha-emitting daughter radionuclides. Thus, there is a high interest in having a source of 211At for sale to investigators in the US. Production of 211At is accomplished on a cyclotron using an alpha-particle beam irradiation of bismuth metal. Unfortunately, there are few cyclotrons available that can produce an alpha particle beam for that production. The University of Washington has a cyclotron, one of three in the U.S., that is currently producing 211At. In the proposed studies, the things necessary for production and shipment of 211At to other investigators will be put into place at UW. Of major importance is the efficient production and isolation of 211At in a form that can be readily used by other investigators. In the studies, production of 211At on the UW cyclotron will be optimized by determining the best beam energy and the highest beam current to maximize 211At production. As it would be very difficult for most investigators to isolate the 211At from the irradiated target, the 211At-isolation process will be optimized and automated to more safely and efficiently obtain the 211At for shipment. Additional tasks to make the 211At available for distribution include obtaining appropriate shipping vials and containers, putting into place the requisite standard operating procedures for Radiation Safety compliance at the levels of 211At activity to be produced / shipped, and working with the Department of Energy, Isotope Development and Production for Research and Applications Program, to take orders, make shipments and be reimbursed for costs of production and shipment.

  8. Inclusive measurement of (p,πsup(-)xn) double charge exchange reactions on bismuth from threshold to 800 MeV

    International Nuclear Information System (INIS)

    The energy dependence of the total angle-integrated cross section for the production of astatine isotopes from (p,πsup(-)xn) double charge exchange reactions on bismuth (sup(209)Bi) was measured from 120 to 800 MeV using activation and radiochemical techniques. Chemical yields were estimated by direct radioassaying of sup(211)At activity in thin (approximately 1 mg/cmsup(2)), irradiated bismuth targets. Calculations of the contributions of secondary (2-step) reactions to these measured astatine yields were performed, based partially upon the observed sup(211)At activity although even at the highest energies, the contribution to products lighter than sup(207)At was negligible. These data for products with as many as 7 neutrons removed from the doubly coherent product (sup(210)At) display nearby gaussian shapes for the mass distributions of the astatine residues with the maximum occurring for about sup(204)At. The most probable momentum transfer deduced from these distributions for the initial πsup(-) production step was 335 MeV/c. The observed excitation functions display a behaviour similar to that observed for the yield of sup(210)Po from a (p,πsup(O)) reaction on sup(209)Bi, but radically different from that observed for inclusive πsup(-) reactions on a heavy nucleus. These data are discussed in terms of recent theoretical approaches to negative pion production from bismuth. In addition, a simple, schematic model is developed to treat the rapidly decreasing percentage of the total inclusive πsup(-) emission which is observed for this double charge exchange reaction. This model reflects the capacity of a nucleus to a source of internal energetic protons

  9. Contribution to construction and setup of a detection system for the focal plan of the BBS spectrometer. Application to study of the neutron emission decay of the resonant states populated by the reaction (4He,3He) at 42 MeV/u in nuclei 208Pb and 209Pb

    International Nuclear Information System (INIS)

    In order to realize an experimental program dedicated to nuclear structure studies we have conceived and constructed at IPN Orsay a detection system for the focal plane of the magnetic spectrometer BBS, installed at the cryogenic cyclotron AGOR of the laboratory KVI (The Netherlands). Two detection units, consisting each of two localization plans of the Cathode Strip Chamber (CSC) type, measure the position and angle of particle trajectory. This information is used for the determination of the reaction parameters at the target by a backtracking procedure. The identification of the reaction products is done by the measurement of their time-of-flight and energy loss. For light ions this task is assumed by plastic scintillators, and for heavy ions by a parallel plan detector (PPAC) and an ionization chamber. This detection system is well adapted to the requirements given by the detection of a large range of ions (protons to 36Ar at energies of several tenths of MeV/nucleon) as well as the big acceptance, the small dispersion and the aberration of the BBS. The results of the test show the good performances of the detection system. In a first experiment the focal plane detection system was coupled to the neutron multidetector EVEN in order to study the decay of resonant high spin states at high excitation energies by the (4He, 3He) reaction on 207Pb and 208Pb targets. The transfer spectra, inclusive and in coincidence, of the nuclei 208Pb and 209Pb show a striking resemblance except for an excitation energy shift which is due to the hole in the last neutron shell of 207Pb. The resonances at l 8 and l = 9 are clearly populated, in agreement with the predictions of the Bonaccorso-Brink model. A sizeable fraction of the decay of the l = 8 resonance is direct, but at excitation energies higher than 15 MeV (in 208Pb) the decay is mostly statistical. (author)

  10. 33 CFR 209.340 - Laboratory investigations and materials testing.

    Science.gov (United States)

    2010-07-01

    ... will directly contribute to a specific planning, design, or construction activity which derives its... Project, St. Anthony Falls Laboratory, University of Minnesota, Minneapolis, Minnesota. The District... will be performed on a cost reimbursable basis. (2) Work may be performed for State and local units...

  11. 48 CFR 1352.209-74 - Organizational conflict of interest.

    Science.gov (United States)

    2010-10-01

    ... Organizational conflict of interest. As prescribed in 48 CFR 1309.507-2(d), insert the following clause: Organizational Conflict of Interest (APR 2010) (a) Purpose. The purpose of this clause is to ensure that the... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Organizational conflict...

  12. 44 CFR 209.10 - Project implementation requirements.

    Science.gov (United States)

    2010-10-01

    ... requirements, 44 CFR part 13, the grant agreement, and with applicable Federal, State, and local laws and... assistance; insurance settlements; legal settlements; Small Business Administration loans; and any other... agricultural purposes; and (ii) Take measures to bring a non-compliant parcel back into compliance within...

  13. The underground research laboratory room 209 excavation response test

    International Nuclear Information System (INIS)

    The response of the rock mass to excavation is an important factor in the design and performance of underground excavations and installations. This is particularly true in the excavation of vaults for the disposal of nuclear fuel waste, where the conditions in the rock mass around the disposal areas may affect the performance of engineered sealing systems installed to isolate the waste. The factors influencing, and mechanisms controlling, rock mass response to excavation must be understood in order to accommodate excavation response effects in disposal vault design and construction

  14. 48 CFR 15.209 - Solicitation provisions and contract clauses.

    Science.gov (United States)

    2010-10-01

    ... of commercial items exempted under 15.403-1. (2)(i) When using funds appropriated or otherwise made... REGULATION CONTRACTING METHODS AND CONTRACT TYPES CONTRACTING BY NEGOTIATION Solicitation and Receipt...

  15. 24 CFR 1710.209 - Title and land use.

    Science.gov (United States)

    2010-04-01

    ... any documentation which evidences the developers' authorization to develop and/or sell the land. (2... acceptable for such purposes in the political subdivision where the land is located. (B) A clear delineation... the subdivision on the environment, submit a summary of that study. (3) Restrictions or...

  16. 29 CFR 825.209 - Maintenance of employee benefits.

    Science.gov (United States)

    2010-07-01

    ... not increase in the event the employment relationship terminates. (b) The same group health plan..., hospital care, dental care, eye care, mental health counseling, substance abuse treatment, etc., must be... FMLA ceases if and when the employment relationship would have terminated if the employee had not...

  17. 28 CFR 36.209 - Illegal use of drugs.

    Science.gov (United States)

    2010-07-01

    ... rehabilitation program; or (iii) Is erroneously regarded as engaging in such use. (b) Health and drug... connection with drug rehabilitation, to an individual on the basis of that individual's current illegal use of drugs, if the individual is otherwise entitled to such services. (2) A drug rehabilitation...

  18. n-Alcohol/Water Partition Coefficients for Decachlorobiphenyl (PCB 209)

    Science.gov (United States)

    Measurements of n-octanol/water partition coefficients (Kow) for highly hydrophobic chemicals are extremely difficult and are rarely made, in part due to the large volumes of water typically needed to quantify these compounds in the aqueous phase. An extrapolation approach using ...

  19. Dicty_cDB: VFL209 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available se catalytic subunit A;... 413 e-114 AB093512_1( AB093512 |pid:none) Saccharomyces pastorianus VMA1 gen... 2...83 9e-75 AB093514_1( AB093514 |pid:none) Saccharomyces pastorianus VMA1 gen... 283 9e-75 ( P17255 ) RecName:...-74 AB093513_1( AB093513 |pid:none) Saccharomyces pastorianus VMA1 gen... 279 1e-

  20. 49 CFR 1540.209 - Fees for security threat assessment.

    Science.gov (United States)

    2010-10-01

    ... current cost of conducting security threat assessments. TSA determines fee amounts and any necessary revisions to the fee amounts based on current costs, using a method of analysis consistent with widely accepted accounting principles and practices, and calculated in accordance with the provisions of 31...

  1. Diagnose in beeld (209). Een te water geraakte man

    NARCIS (Netherlands)

    van Noord, T; Ligtenberg, J J M; Zijlstra, J G

    2004-01-01

    A 32-year-old man was presented with severe hypothermia and respiratory insufficiency after submersion in water. The ECG showed Osborn waves and a prolonged QRS and QT duration which normalized after correction of the hypothermia.

  2. 40 CFR 180.209 - Terbacil; tolerances for residues.

    Science.gov (United States)

    2010-07-01

    ... terbacil, in or on the following raw agricultural commodities: Commodity Parts per million Alfalfa, forage 1.0 Alfalfa, hay 2.0 Apple 0.3 Asparagus 0.4 Blueberry 0.2 Caneberry subgroup 13A 0.2 Peach...

  3. Dicty_cDB: SSL209 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available iva ameiva ... 33 6.5 CP001280_47( CP001280 |pid:none) Methylocella silvestris BL2,... EU254537_1( EU254537 |pid:none) Plasmodium sp. br67 cytochrome b (... 33 6.5 AY099047_1( AY099047 |pid:none) Plasmodium sp. from Ame

  4. 44 CFR 209.8 - Application and review process.

    Science.gov (United States)

    2010-10-01

    ... processing subgrants to applicants in accordance with 44 CFR part 13 and this part. (b) Timeframes. We will... historic preservation that is readily available; (9) Attachments for each property as follows: (i) A... list (provide NFIP Repetitive Loss Property Locator Number, if available); and (xiii) Observations...

  5. 48 CFR 1352.209-71 - Limitation of future contracting.

    Science.gov (United States)

    2010-10-01

    ... Limitation of future contracting. As prescribed in 48 CFR 1309.507-2(a), insert the following clause... obtaining an unfair competitive advantage in concurrent or future acquisitions. (1) Descriptions or... 48 Federal Acquisition Regulations System 5 2010-10-01 2010-10-01 false Limitation of...

  6. 48 CFR 3052.209-73 - Limitation of future contracting.

    Science.gov (United States)

    2010-10-01

    ... in (HSAR) 48 CFR 3009.507-2, the contracting officer may insert a clause substantially as follows in...: (1) If the Contractor, under the terms of this contract, or through the performance of tasks pursuant to this contract, is required to develop specifications or statements of work that are to...

  7. 48 CFR 1852.209-71 - Limitation of future contracting.

    Science.gov (United States)

    2010-10-01

    ...: (1) If the Contractor, under the terms of this contract, or through the performance of tasks pursuant to this contract, is required to develop specifications or statements or work that are to be... to prepare such specifications or statements of work under this contract. (2) To the extent that...

  8. 48 CFR 1552.209-74 - Limitation of future contracting.

    Science.gov (United States)

    2010-10-01

    ..., or through the performance of work pursuant to this contract, is required to develop specifications... subcontract under an EPA contract, which supports EPA's performance of Superfund Headquarters policy work... companies. (b) If the Contractor, under the terms of this contract, or through the performance of...

  9. 48 CFR 952.209-72 - Organizational conflicts of interest.

    Science.gov (United States)

    2010-10-01

    ... competitive advantage over other parties by virtue of its performance of this contract. (b) Scope. The... unsolicited) which stem directly from the Contractor's performance of work under this contract for a period of (Contracting Officer see 48 CFR 909.507-2 and enter specific term) years after the completion of this...

  10. Dicty_cDB: SSK209 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available d Amino Acid sequence nqyh*nn*NMMMMMKMMKTKMIKRKRKHLVNMVINVIVNQLITLKNFHIHS*likfnfrf *k*nkik*nkik*nknkksndclil...RKHLVNMVINVIVNQLITLKNFHIHS*likfnfrf *k*nkik*nkik*nknkksndclilkn Frame B: tntirtiri*****r**rrr*lkekestl*iw**m

  11. 34 CFR 685.209 - Income contingent repayment plan.

    Science.gov (United States)

    2010-07-01

    ... Consumer Price Index (as determined by the Secretary) between December 1995 and the December next preceding... AGI does not reasonably reflect the borrower's current income, the Secretary may use other... consent form, developed consistent with 26 CFR 301.6103(c)-1 and provided to the borrower by the...

  12. Dicty_cDB: SFL209 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available update 2001. 6. 1 Translated Amino Acid sequence nxflxyky*ihilffyil*HFIKKKKKKKXKKXPFXKKK--- ---VKTKXQDXEGIPPDQQRXIXRW*xixxmxxls...nsyfiflyivtfhkkkkkkkx*kxpfxekk--- ---m*kxxfkixkvfpxinnvsfxvgxqxrxcxxsl*lqypkrixlshlvxrlrgwyxnl cqninw*dhhs*s... ixfyxtnikfifyffiycnis*kkkkkkxlkxplfxkkk--- ---VKTKXQDXEGIPPDQQRXIXRW*xixxmxxlslitiskknxtxplgxqikrvvxksl skh

  13. Contribution to construction and setup of a detection system for the focal plan of the BBS spectrometer. Application to study of the neutron emission decay of the resonant states populated by the reaction ({sup 4}He,{sup 3}He) at 42 MeV/u in nuclei {sup 208}Pb and {sup 209}Pb; Contribution a la construction et a la mise au point d'un systeme de detection pour le plan focal du spectrometre BBS. Application a l'etude de la decroissance par emission de neutrons d'etats resonants peuples par la reaction ({sup 4}He,{sup 3}He) a 42 MeV/u dans les noyaux {sup 208}Pb et {sup 209}Pb

    Energy Technology Data Exchange (ETDEWEB)

    Plankl-Chabib, Elke [Inst. de Physique Nucleaire, Paris-11 Univ., 91 - Orsay (France)

    1999-06-11

    In order to realizean experimental program dedicated to nuclear structure studies we have conceived and constructed at IPN Orsay a detection system for the focal plane of the magnetic spectrometer BBS, installed at the cryogenic cyclotron AGOR of the laboratory KVI (The Netherlands). Two detection units, consisting each of two localization plans of the Cathode Strip Chamber (CSC) type, measure the position and angle of particle trajectory. This information is used for the determination of the reaction parameters at the target by a backtracking procedure. The identification of the reaction products is done by the measurement of their time-of-flight and energy loss. For light ions this task is assumed by plastic scintillators, and for heavy ions by a parallel plan detector (PPAC) and an ionization chamber. This detection system is well adapted to the requirements given by the detection of a large range of ions (protons to {sup 36}Ar at energies of several tenths of MeV/nucleon) as well as the big acceptance, the small dispersion and the aberration of the BBS. The results of the test show the good performances of the detection system. In a first experiment the focal plane detection system was coupled to the neutron multidetector EVEN in order to study the decay of resonant high spin states at high excitation energies by the ({sup 4}He, {sup 3}He) reaction on {sup 207}Pb and {sup 208}Pb targets. The transfer spectra, inclusive and in coincidence, of the nuclei {sup 208}Pb and {sup 209}Pb show a striking resemblance except for an excitation energy shift which is due to the hole in the last neutron shell of {sup 207}Pb. The resonances at l 8 and l = 9 are clearly populated, in agreement with the predictions of the Bonaccorso-Brink model. A sizeable fraction of the decay of the l = 8 resonance is direct, but at excitation energies higher than 15 MeV (in {sup 208}Pb) the decay is mostly statistical.

  14. An all-solid state laser system for the laser ion source RILIS and in-source laser spectroscopy of astatine at ISOLDE,CERN

    OpenAIRE

    Rothe, Sebastian

    2012-01-01

    This doctoral thesis describes the extension of the resonance ionization laser ion source RILIS at CERN/ISOLDE by the addition of an all-solid state tunable titanium:sapphire (Ti:Sa) laser system to complement the well-established system of dye lasers. Synchronous operation of the so called Dual RILIS system of Ti:Sa and dye lasers was investigated and the potential for increased ion beam intensity, reliability, and reduced setup time has been demonstrated. In-source resonance ionization spec...

  15. Linear motor system for sliding door for 209-series 950-generation electric railcar; 209 kei 950 dai densha soku hikidoyo rinia motor system

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-01-10

    The system named above has been delivered to East Japan Railway Co. by Fuji Electric Co., Ltd., for use aboard the railway company`s prototype car to close the sliding door and is now in test use, the car designed to carry both commuters and suburbanites. This is the first product of the linear motor-driven type intended to close the sliding door aboard a railway car. Some features are stated below. The door lock and the door lock disengagement unit are improved, with their reliability enhanced. TIMS (train information management system) control and transmission enable the opening and closing of the door, supervision over the individual door state, parameter rewriting, etc., from the driver`s cab. Some base boards are added for shortening the rigging process. It is planned that a 1-linear motor drive system will be manufactured, lighter in weight, lower in power consumption, enhanced in safety, and reduced in cost, for installation aboard the car. (NEDO)

  16. 34 CFR 300.209 - Treatment of charter schools and their students.

    Science.gov (United States)

    2010-07-01

    ... schools that are public schools of the LEA. (1) In carrying out Part B of the Act and these regulations with respect to charter schools that are public schools of the LEA, the LEA must— (i) Serve children... the site to its other public schools; and (ii) Provide funds under Part B of the Act to those...

  17. The Mars Hand Lens Imager (MAHLI) for the 209 Mars Science Laboratory

    Science.gov (United States)

    Edgett, K. S.; Bell, J. F., III; Herkenhoff, K. E.; Heydari, E.; Kah, L. C.; Minitti, M. E.; Olson, T. S.; Rowland, S. K.; Schieber, J.; Sullivan, R. J.

    2005-01-01

    The MArs Hand Lens Imager (MAHLI) is a small, RGB-color camera designed to examine geologic material at 12.5-75 microns/pixel resolution at the Mars Science Laboratory (MSL) landing site. MAHLI is a PI-led investigation competitively selected by NASA in December 2004 as part of the science payload for the MSL rover launching in 2009. The instrument is being fabricated by, and will be operated by, Malin Space Science Systems of San Diego, California.

  18. 24 CFR 1003.209 - Prohibition on use of assistance for employment relocation activities.

    Science.gov (United States)

    2010-04-01

    ... constitute a significant loss of jobs. (ii) A job is considered to be lost due to the provision of ICDBG... job loss as defined in this rule. (d) Assistance not covered by this section. This section does not... loss of jobs in the Identified Service Area from which the relocation occurs. (b) Definitions....

  19. Sam Ting at the ISR intersection I-2 (experiment R209)

    CERN Multimedia

    1976-01-01

    The Genova-Harvard-MIT-Pisa Collaboration, later CERN-Harvard-Frascati-MIT-Naples-Pisa Collaboration, set up an experiment to search for the electromagnetic properties of protons in the time-like region and search for the neutral boson Z0 (Muon pair production)

  20. 33 CFR 209.141 - Coordination of hydroelectric power operations with power marketing agencies.

    Science.gov (United States)

    2010-07-01

    ... civil works field operating agencies (FOA) having generating facilities producing marketable electric... recovering Federal investment are the responsibilities of the power marketing agencies. (2) All FOA... marketing agency will be notified of that fact in writing. (2) FOA responsibility. The FOA...

  1. Measurement of neutron total cross-sections of 209Bi at the Pohang Neutron Facility

    CERN Document Server

    Wang, Tao-Feng; Kim, Guinyun

    2014-01-01

    Measurements of neutron total cross-sections of natural bismuth in the neutron energy region from 0.1 eV to 100 eV have been performed by using the time-of-flight method at the Pohang Neutron Facility, which consists of an electron linear accelerator, a water-cooled tantalum target with a water moderator, and a 12-m-long time-of-flight path. A 6Li-ZnS(Ag) scintillator with a diameter of 12.5 cm and a thickness of 1.6 cm is employed as a neutron detector, and a piece of high purity natural bismuth metallic plates with a thickness of 3 mm is used for the neutron transmission measurement. The present results were compared with the evaluated data from ENDF/B VII.1 and other previous reported experimental data.

  2. Study of ZZ Production at LEP at √s=183 - 209 GeV

    Science.gov (United States)

    Pásztor, Gabriella

    A study of Z boson pair production in e+e- annihilation using the OPAL detector at LEP is reported . The ZZ production cross-section is measured, limits on anomalous ZZγ and ZZZ couplings are derived, and constraints on models of low scale quantum gravity in extra spatial dimensions are set.

  3. Study of ZZ production at LEP at $\\sqrt{s}$ = 183-209 GeV

    CERN Document Server

    Pásztor, G

    2001-01-01

    A study of Z boson pair production in e+e- annihilation using the OPAL detector at LEP is reported. The ZZ production cross-section is measured, limits on anomalous ZZgamma and ZZZ couplings are derived, and constraints on models of low scale quantum gravity in extra spatial dimensions are set.

  4. 48 CFR 252.209-7007 - Prohibited Financial Interests for Lead System Integrators.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Prohibited Financial... Financial Interests for Lead System Integrators (JUL 2009) (a) Definitions. As used in this clause— (1) Lead... system responsibility. Unless an exception is granted, the Contractor shall not have any direct...

  5. 48 CFR 3052.209-75 - Prohibited financial interests for lead system integrators.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 7 2010-10-01 2010-10-01 false Prohibited financial... interests for lead system integrators. As prescribed in (HSAR) 48 CFR 3009.570-4(b), use the following clause: PROHIBITED FINANCIAL INTERESTS FOR LEAD SYSTEM INTEGRATORS (JUL 2010) (a) Definitions. As used...

  6. SU-E-J-209: Verification of 3D Surface Registration Between Stereograms and CT Images

    Energy Technology Data Exchange (ETDEWEB)

    Han, T; Gifford, K [UT MD Anderson Cancer Center, Houston, TX (United States); Smith, B [MD Anderson Cancer Center, Houston, TX (United States); Salehpour, M [M.D. Anderson Cancer Center, Houston, TX (United States)

    2014-06-01

    Purpose: Stereography can provide a visualization of the skin surface for radiation therapy patients. The aim of this study was to verify the registration algorithm in a commercial image analysis software, 3dMDVultus, for the fusion of stereograms and CT images. Methods: CT and stereographic scans were acquired of a head phantom and a deformable phantom. CT images were imported in 3dMDVultus and the surface contours were generated by threshold segmentation. Stereograms were reconstructed in 3dMDVultus. The resulting surfaces were registered with Vultus algorithm and then exported to in-house registration software and compared with four algorithms: rigid, affine, non-rigid iterative closest point (ICP) and b-spline algorithm. RMS (root-mean-square residuals of the surface point distances) error between the registered CT and stereogram surfaces was calculated and analyzed. Results: For the head phantom, the maximum RMS error between registered CT surfaces to stereogram was 6.6 mm for Vultus algorithm, whereas the mean RMS error was 0.7 mm. For the deformable phantom, the maximum RMS error was 16.2 mm for Vultus algorithm, whereas the mean RMS error was 4.4 mm. Non-rigid ICP demonstrated the best registration accuracy, as the mean of RMS errors were both within 1 mm. Conclusion: The accuracy of registration algorithm in 3dMDVultus was verified and exceeded RMS of 2 mm for deformable cases. Non-rigid ICP and b-spline algorithms improve the registration accuracy for both phantoms, especially in deformable one. For those patients whose body habitus deforms during radiation therapy, more advanced nonrigid algorithms need to be used.

  7. 48 CFR 3052.209-71 - Reserve Officer Training Corps and military recruiting on campus.

    Science.gov (United States)

    2010-10-01

    ...) Definitions. Institution of higher education, as used in this clause, means an institution that meets the requirements of 20 U.S.C. 1001 and includes all subelements of such an institution. (b) Limitation on contract... Training Corps and military recruiting on campus. As prescribed in (HSAR) 48 CFR 3009.470-4, use...

  8. 48 CFR 3052.209-70 - Prohibition on contracts with corporate expatriates.

    Science.gov (United States)

    2010-10-01

    ... contracts with corporate expatriates. As prescribed at (HSAR) 48 CFR 3009.104-75, insert the following... former shareholders of the domestic corporation by reason of holding stock in the domestic corporation... Revenue Code of 1986) shall be treated as a partnership. (e) Treatment of Certain Rights. (1)...

  9. Fission fragment mass distribution studies for 28Si + 197Au, 209Bi, 235U reactions

    International Nuclear Information System (INIS)

    In reactions with heavy ions, complete fusion and quasi-fission are the competing processes at energies above the Coulomb barrier. The quasi-fission process, in which the system reseparates before reaching a compact compound nucleus, is a major hurdle in forming heavy and superheavy evaporation residues (ER) in heavy-ion reactions. Fission fragment mass distribution for the fully equilibrated compound nucleus is decided at the scission point due to a long descent from saddle to scission. At higher excitation energies, the shell effects are washed out and the mass distribution is expected to be symmetric. The width of the distribution strongly depends on the entrance channel properties, such as mass asymmetry, deformation of interacting nuclei, collision energy, and the Coulomb factor Z1 Z2. Any sudden change in the width of the mass distribution would indicate departure from full equilibration, while onset of mass asymmetry or a sudden increase in width would be a strong signal of quasi fission

  10. 48 CFR 252.209-7006 - Limitations on Contractors Acting as Lead System Integrators.

    Science.gov (United States)

    2010-10-01

    ... construction of any individual system or element of any system of systems. (c) Representations. (1) The offeror...(s), system of systems, or services described in this solicitation. (d) If the offeror answered...

  11. 48 CFR 3052.209-74 - Limitations on contractors acting as lead system integrators.

    Science.gov (United States)

    2010-10-01

    ... individual system or element of any system of systems. (c) Representations. (1) The offeror represents that... financial interest in the development or construction of any system(s), subsystem(s), system of systems, element of any system of systems, or services it proposes or intends to seek to satisfy this...

  12. 49 CFR Appendix B to Part 209 - Federal Railroad Administration Guidelines for Initial Hazardous Materials Assessments

    Science.gov (United States)

    2010-10-01

    ... committed the acts due to a failure to exercise reasonable care under the circumstances (“knowingly”). For... example, the guidelines for shipping paper violations at 49 CFR §§ 172.200-.203. All penalties in these... confusion, these penalty guidelines use the notion of “human contact” to trigger penalty aggravation....

  13. Uptake, translocation and metabolism of decabromodiphenyl ether (BDE-209) in seven aquatic plants.

    Science.gov (United States)

    Deng, Daiyong; Liu, Jin; Xu, Meiying; Zheng, Guolu; Guo, Jun; Sun, Guoping

    2016-06-01

    Terrestrial plant uptake of PBDEs from contaminated soils has been widely reported recently. In this study the fate of deca-BDE within a plant/PBDEs/aquatic environment system was investigated through simulated pot experiments. Accumulations of the total PBDEs and deca-BDE were observed in tissues of seven test aquatic plant species, namely Phragmites australis, Cyperus papyrus, Alternanthera philoxeroides, Colocasia esculenta, Scirpus validus, Acorus calamus and Oryza sativa. In all seven plants, O. sativa leads the uptake and accumulation both in the total PBDEs (444.8 ng g(-1)) and deca-BDE (368.0 ng g(-1)) in roots. Among the six common phytoremediation aquatic plants, A. calamus leads the uptake (236.2 ng g(-1)), and P. australis leads the translocation (Cshoot/Croot = 0.35), while A. philoxeroides (43.4%) and P. australis (80.0%) lead in the metabolism efficiencies in the root and shoot, respectively. The detection of seventeen lesser brominated PBDE congeners provided the debromination evidence, and the specific PBDEs profiles in test plant species indicated there is no common metabolic pattern. Furthermore, a relative high proportion of lesser brominated PBDE congeners in shoots suggested the possible metabolic difference between roots and shoots. Finally, a noticeable percentage of penta- and octa-BDE derived from deca-BDE also hint the ecological risk in deca-BDE use. This comparative research on the aquatic plants provide a broad vision on the understanding of plant/PBDEs/aquatic environment interaction system, and may be applied to remediate PBDEs in contaminated waters and sediments. PMID:26994429

  14. 40 CFR 600.209-85 - Calculation of fuel economy values for labeling.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Calculation of fuel economy values for... (CONTINUED) ENERGY POLICY FUEL ECONOMY AND CARBON-RELATED EXHAUST EMISSIONS OF MOTOR VEHICLES Fuel Economy Regulations for 1977 and Later Model Year Automobiles-Procedures for Calculating Fuel Economy Values §...

  15. 40 CFR 600.209-95 - Calculation of fuel economy values for labeling.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 29 2010-07-01 2010-07-01 false Calculation of fuel economy values for... (CONTINUED) ENERGY POLICY FUEL ECONOMY AND CARBON-RELATED EXHAUST EMISSIONS OF MOTOR VEHICLES Fuel Economy Regulations for 1977 and Later Model Year Automobiles-Procedures for Calculating Fuel Economy Values §...

  16. 24 CFR 570.209 - Guidelines for evaluating and selecting economic development projects.

    Science.gov (United States)

    2010-04-01

    ... equity investment will not be unreasonably high; and (6) That to the extent practicable, CDBG funds are... residents of an area pursuant to a strategy approved by HUD under the provisions of § 91.215(e) of this title; (M) Creates or retains jobs through businesses assisted in an area pursuant to a...

  17. 48 CFR 2152.209-71 - Certification regarding debarment, suspension, proposed debarment, and other responsibility matters.

    Science.gov (United States)

    2010-10-01

    ... Federal Acquisition Regulations System OFFICE OF PERSONNEL MANAGEMENT, FEDERAL EMPLOYEES GROUP LIFE..., theft, forgery, bribery, falsification or destruction of records, making false statements, or...

  18. 48 CFR 2052.209-71 - Contractor organizational conflicts of interest (representation).

    Science.gov (United States)

    2010-10-01

    ... Organizational Conflicts of Interest Representation (OCT 1999) I represent to the best of my knowledge and belief... representation, as completed, indicates that situations or relationships of the type set forth in 48 CFR 2009.570... provisions of 48 CFR 2009-570-9. (b) The refusal to provide the representation required by 48 CFR...

  19. 29 CFR 779.209 - Vertical activities which are “related activities.”

    Science.gov (United States)

    2010-07-01

    ... structure such as the manufacturing, warehousing, and retailing of a particular product or products.” Where... business activities, such as a wholesaling and retailing or manufacturing and retailing, are interrelated... to carry out a business purpose of the manufacturing plant, retailing and manufacturing will...

  20. 23 CFR 420.209 - What are the conditions for approval?

    Science.gov (United States)

    2010-04-01

    ... management process that identifies and results in implementation of RD&T activities expected to address high priority transportation issues. The management process must include: (1) An interactive process for... management process in implementing the RD&T program, to determine the utilization of the State DOT's...

  1. Yeast Interacting Proteins Database: YGR209C, YDL081C [Yeast Interacting Proteins Database

    Lifescience Database Archive (English)

    Full Text Available ects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a cofactor for Tsa...ystem which protects cells against oxidative and reductive stress, forms LMA1 complex with Pbi2p, acts as a

  2. 49 CFR 1542.209 - Fingerprint-based criminal history records checks (CHRC).

    Science.gov (United States)

    2010-10-01

    ... certification to an airport operator pursuant to paragraph (n) of this section, or 14 CFR 108.31(n) in effect prior to November 14, 2001 (see 14 CFR Parts 60 to 139 revised as of January 1, 2001). An airport user... disqualifying criminal offense. (iii) A statement informing the individual that Federal regulations under 49...

  3. 47 CFR 54.209 - Annual reporting requirements for designated eligible telecommunications carriers.

    Science.gov (United States)

    2010-10-01

    ... 911 special facility, as defined in 47 CFR 4.5(e). (iii) Specifically, the eligible telecommunications... CFR 4.5, of at least 30 minutes in duration for each service area in which an eligible... 47 Telecommunication 3 2010-10-01 2010-10-01 false Annual reporting requirements for...

  4. 33 CFR 209.310 - Representation of submarine cables and pipelines on nautical charts.

    Science.gov (United States)

    2010-07-01

    ... submarine cable and pipelines to the National Oceanic and Atmospheric Administration (NOAA), National Ocean... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Representation of submarine... of submarine cables and pipelines on nautical charts. (a) The policy of the Corps of Engineers...

  5. 48 CFR 2452.209-70 - Potential organizational conflicts of interest.

    Science.gov (United States)

    2010-10-01

    ... competitive advantage. The offeror may also provide relevant facts that show how its organizational structure and/or management systems limit its knowledge of possible organizational conflicts of interest... 48 Federal Acquisition Regulations System 6 2010-10-01 2010-10-01 true Potential...

  6. 75 FR 51332 - Eleventh Meeting: RTCA Special Committee 209: In Joint Session With EUROCAE WG-49: ATCRBS/Mode S...

    Science.gov (United States)

    2010-08-19

    ...) Review of the Status of Open Action Items AI-10-11--Review of Documents for P5 Pulse Position Differences (WP11-03) AI-10-03--Issues Related to Zeroing Registers 08 16 & 20 16 (WP11-04) AI-10-02--Register 60 16 Maximum Update Interval Changes (WP11-05) AI-10-01--Errata for Register 60 16 for GPS Data Input...

  7. 18 CFR 376.209 - Procedures during periods of emergency requiring activation of the Continuity of Operations Plan.

    Science.gov (United States)

    2010-04-01

    ... on requests to ensure continued construction of essential natural gas facilities with sensitive construction timelines, on Commencement of Service requests, and on completion of dam safety work, in a manner... major wire services, industry press, and appropriate metropolitan area radio stations announcing...

  8. 49 CFR 350.211 - What is the format of the certification required by § 350.209?

    Science.gov (United States)

    2010-10-01

    ... laws or regulations. 8. The State must maintain the average aggregate expenditure of the State and its... eligible for funding under the Basic program at a level at least equal to the average level of expenditure... each Government fiscal year. These expenditures must cover at least the following four program...

  9. 75 FR 12968 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217C, and -219 Turbofan Engines

    Science.gov (United States)

    2010-03-18

    ... (62 FR 4902). ADDRESSES: You can get the service information identified in this AD from Pratt... proposed AD in the Federal Register on December 21, 2009 (74 FR 67831). That action proposed to require...'' under DOT Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); and (3) Will not have...

  10. 75 FR 38052 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217A, -217C, and -219 Series Turbofan...

    Science.gov (United States)

    2010-07-01

    ... April 11, 2000 (65 FR 19477-78). Examining the AD Docket You may examine the AD docket on the Internet... 39 by superseding AD 2005-02- 03, Amendment 39-13948 (70 FR 3867, January 27, 2005). That AD requires... Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); and 3. Would not have a...

  11. 76 FR 16526 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217A, -217C, and -219 Series Turbofan...

    Science.gov (United States)

    2011-03-24

    ...We are superseding an existing airworthiness directive (AD) for the products listed above. That AD currently requires initial and repetitive torque inspections of the 3rd stage and 4th stage low- pressure turbine (LPT) blades for shroud notch wear and replacement of the blade if wear limits are exceeded. That AD also requires replacing LPT-to-exhaust case bolts and nuts with bolts and nuts......

  12. 75 FR 50945 - Airworthiness Directives; Pratt & Whitney JT8D-209, -217, -217A, -217C, and -219 Turbofan Engines

    Science.gov (United States)

    2010-08-18

    ... complete Privacy Act Statement in the Federal Register published on April 11, 2000 (65 FR 19477-78...-02, Amendment 39-14242 (70 FR 52004, September 1, 2005), to require revisions to the TLS of the... Regulatory Policies and Procedures (44 FR 11034, February 26, 1979); and 3. Would not have a...

  13. 48 CFR 3052.209-76 - Prohibition on Federal Protective Service guard services contracts with business concerns owned...

    Science.gov (United States)

    2010-10-01

    ... or business ethics and that an award would be consistent with the mission of FPS. The business... longer calls into question the individual or business concern's integrity or business ethics and that an... Protective Service guard services contracts with business concerns owned, controlled, or operated by...

  14. Amino acid 1-209 is essential for PDX-1-mediated repression of human CMV IE promoter activity

    Institute of Scientific and Technical Information of China (English)

    Jing CHEN; Lei CHEN; Ge LI; Lu CHENG; Yin HUANG; Jia-xin ZHANG; Wei-wei FAN; Da-ru LU

    2006-01-01

    Aim: To explore the different roles of pancreatic duodenal homeobox factors-1 (PDX-1) domains in PDX-1 mediated repression of human cytomegalovirus immediately early (CMV IE) promoter. Methods: A series of truncated PDX-1 mutants were constructed. The binding of PDX-1 and CMV IE promoter was identified by electrophoretic mobility shift assay (EMSA). The dual-reporter assay was applied to examine the repression activities of PDX-1 mutants on CMV IE promoter. In addition, RNAi technology was used to specifically knock down the endogenous PDX-1 expression. Results: The reporter assay indicated that compared to the mock controls (pEGFP-N2), overexpression of PDX-1 resulted in a 41% decrease of CMV IE promoter activity in the 293 cells (P<0.05) and 43% decrease in HeLa cells (P<0.05), and the repression levels of various truncated mutants played on CMV IE promoter were different. Specific knock down of the endogenous PDX-1 expression significantly restored the activity of CMV IE promoter. EMS A demonstrated that domain 3 is necessary for nuclear localization and DNA binding activity of PDX-1. However, binding of PDX-1 alone to CMV IE promoter was not sufficient to inhibit its transcriptional activity, and other domains of PDX-1 presented were also required. Conclusion: Our data suggested that the DNA binding activity of PDX-1 domain 3 and the cooperative binding of PDX-1 domain 1/2 with other proteins were required for PDX-1 mediated repression of CMV IE promoter.

  15. SU-E-J-209: Geometric Distortion at 3T in a Commercial 4D MRI-Compatible Phantom

    Energy Technology Data Exchange (ETDEWEB)

    Fatemi-Ardekani, A; Wronski, M; Kim, A; Stanisz, G; Sarfehnia, A; Keller, B [Sunnybrook Health Sciences Centre, Toronto, ON (Canada)

    2015-06-15

    Purpose: There are very few commercial 4D phantoms that are marketed as MRI compatible. We are evaluating one such commercial phantom, made to be used with an MRI-Linear accelerator. The focus of this work is to characterize the geometric distortions produced in this phantom at 3T using 3 clinical MR pulse sequences. Methods: The CIRS MRI-Linac Dynamic Phantom (CIRSTM) under investigation in this study consists of a softwaredriven moving tumour volume within a thorax phantom body and enables dose accumulation by placing a dosimeter within the tumour volume. Our initial investigation is to evaluate the phantom in static mode prior to examining its 4D capability. The water-filled thorax phantom was scanned using a wide-bore Philips 3T Achieva MRI scanner employing a Thoracic xl coil and clinical 2D T1W FFE, 2D T1W TSE and 3D T1W TFE pulse sequences. Each of the MR image sets was rigidly fused with a reference CT image of the phantom employing a rigid registration with 6 degrees of freedom. Geometric distortions between the MR and CT image sets were measured in 3 dimensions at selected points along the periphery of the distortion grid embedded within the phantom body (11.5, 7.5 and 3 cm laterally, ant/post and sup/inf of magnetic isocenter respectively). Results: The maximal measured geometric distortions between the MR and reference CT points of interest were 0.9, 1.8 and 1.3 mm in the lateral, anteriorposterior and cranio-caudal directions, respectively. For all 3 spatial dimensions, the maximal distortions occurred for the FFE pulse sequence. Maximal distortions for the 2D FFE, 2D TSE and 3D TFE sequences were 1, 0.7 and 1.8 mm, respectively. Conclusion: Our initial static investigation of this phantom shows minimal geometric distortions at 3T along the periphery of the embedded grid. CIRS has provided us with a phantom at no charge for evaluation at 3 Tesla.

  16. Orthorectification and Mosaicing of Color Aerial Photographyfor the Main Eight Hawaiian Islands: Oahu (208-209-0516)

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This project is a cooperative effort among the National Ocean Service, National Centers for Coastal Ocean Science, Center for Coastal Monitoring and Assessment; the...

  17. The Salience of Racial Isolation: African Americans' and Latinos' Perceptions of Climate and Enrollment Choices with and without Proposition 209

    Science.gov (United States)

    Kidder, William C.

    2012-01-01

    One of the important arguments by critics of affirmative action is that it actually hurts the students it is supposed to help by subjecting them to the "stigma" of being admitted under policies explicitly seeking campus diversity. Such students, this theory argues, must feel embarrassed and uncomfortable as a result and would prefer to be…

  18. 49 CFR Appendix A to Part 209 - Statement of Agency Policy Concerning Enforcement of the Federal Railroad Safety Laws

    Science.gov (United States)

    2010-10-01

    ... collectively herein as the “older safety statutes”: The Safety Appliance Acts, 45 U.S.C. 1-16; the Locomotive..., steam locomotives, and grade crossing signals apply to these non-insular tourist operations (see 49 CFR... CFR 1.49 (c), (d), (f), (g), and (m). Those statutes include the Federal Railroad Safety Act of...

  19. SU-E-T-209: Independent Dose Calculation in FFF Modulated Fields with Pencil Beam Kernels Obtained by Deconvolution

    Energy Technology Data Exchange (ETDEWEB)

    Azcona, J [Department of Radiation Physics, Clinica Universidad de Navarra (Spain); Burguete, J [Universidad de Navarra, Pamplona, Navarra (Spain)

    2014-06-01

    Purpose: To obtain the pencil beam kernels that characterize a megavoltage photon beam generated in a FFF linac by experimental measurements, and to apply them for dose calculation in modulated fields. Methods: Several Kodak EDR2 radiographic films were irradiated with a 10 MV FFF photon beam from a Varian True Beam (Varian Medical Systems, Palo Alto, CA) linac, at the depths of 5, 10, 15, and 20cm in polystyrene (RW3 water equivalent phantom, PTW Freiburg, Germany). The irradiation field was a 50 mm diameter circular field, collimated with a lead block. Measured dose leads to the kernel characterization, assuming that the energy fluence exiting the linac head and further collimated is originated on a point source. The three-dimensional kernel was obtained by deconvolution at each depth using the Hankel transform. A correction on the low dose part of the kernel was performed to reproduce accurately the experimental output factors. The kernels were used to calculate modulated dose distributions in six modulated fields and compared through the gamma index to their absolute dose measured by film in the RW3 phantom. Results: The resulting kernels properly characterize the global beam penumbra. The output factor-based correction was carried out adding the amount of signal necessary to reproduce the experimental output factor in steps of 2mm, starting at a radius of 4mm. There the kernel signal was in all cases below 10% of its maximum value. With this correction, the number of points that pass the gamma index criteria (3%, 3mm) in the modulated fields for all cases are at least 99.6% of the total number of points. Conclusion: A system for independent dose calculations in modulated fields from FFF beams has been developed. Pencil beam kernels were obtained and their ability to accurately calculate dose in homogeneous media was demonstrated.

  20. Compound list: simvastatin [Open TG-GATEs

    Lifescience Database Archive (English)

    Full Text Available simvastatin SST 00117 ftp://ftp.biosciencedbc.jp/archive/open-tggates/LATEST/Human/in_vitro/simv...astatin.Human.in_vitro.Liver.zip ftp://ftp.biosciencedbc.jp/archive/open-tggates/LATEST/Rat/in_vitro/simv...astatin.Rat.in_vitro.Liver.zip ftp://ftp.biosciencedbc.jp/archive/open-tggates/LATEST/Rat/in_vivo/Liver/Single/simv...archive/open-tggates/LATEST/Rat/in_vivo/Liver/Repeat/simvastatin.Rat.in_vivo.Liver.Repeat.zip ...

  1. AB209. The effect of 4-week pedometer and sleep monitoring programme on asthenospermia patients in information technology workers: a prospective study

    OpenAIRE

    Gao, Ming; Wang, Lei; Liu, Xiang; Sun, Jianhua

    2016-01-01

    Objective In China, information technology (IT) workers face many health problems as a result of the nature of work by computer. For instance, IT workers often work overtime and irregular life (such as staying up late, sedentary, lack of exercise, etc.), IT related occupational diseases are more and more. There are many asthenospermia patients in IT workers in clinic, how to improve sperm-related outcomes of them is a problem for us. Using real-time pedometer and sleep monitoring is an innova...

  2. Study of Multiphoton Final States and Tests of QED in $e^+ e^-$ collisions at $\\sqrt{s}$ up to 209 GeV

    CERN Document Server

    Achard, P; Aguilar-Benítez, M; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alviggi, M G; Anderhub, H; Andreev, V P; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Bajo, A; Baksay, G; Baksay, L; Baldew, S V; Banerjee, S; Banerjee, Sw; Barczyk, A; Barillère, R; Bartalini, P; Basile, M; Batalova, N; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Bellucci, L; Berbeco, R; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Biasini, M; Biglietti, M; Biland, A; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böhm, A; Boldizsar, L; Borgia, B; Bottai, S; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brochu, F; Burger, J D; Burger, W J; Cai, X D; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada, M; Chamizo-Llatas, M; Chang, Y H; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chiefari, G; Cifarelli, Luisa; Cindolo, F; Clare, I; Clare, R; Coignet, G; Colino, N; Costantini, S; de la Cruz, B; Cucciarelli, S; van Dalen, J A; De Asmundis, R; Déglon, P L; Debreczeni, J; Degré, A; Deiters, K; Della Volpe, D; Delmeire, E; Denes, P; De Notaristefani, F; De Salvo, A; Diemoz, M; Dierckxsens, M; Dionisi, C; Dittmar, Michael; Doria, A; Dova, M T; Duchesneau, D; Echenard, B; Eline, A; El-Mamouni, H; Engler, A; Eppling, F J; Ewers, A; Extermann, Pierre; Falagán, M A; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Ferguson, T; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisher, W; Fisk, I; Forconi, G; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gataullin, M; Gentile, S; Giagu, S; Gong, Z F; Grenier, G; Grimm, O; Grünewald, M W; Guida, M; van Gulik, R; Gupta, V K; Gurtu, A; Gutay, L J; Haas, D; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Hirschfelder, J; Hofer, H; Hohlmann, M; Holzner, G; Hou, S R; Hu, Y; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Käfer, D; Kaur, M; Kienzle-Focacci, M N; Kim, J K; Kirkby, Jasper; Kittel, E W; Klimentov, A; König, A C; Kopal, M; Koutsenko, V F; Kräber, M H; Krämer, R W; Krenz, W; Krüger, A; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Levchenko, P M; Li, C; Likhoded, S A; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lü, Y S; Lübelsmeyer, K; Luci, C; Luminari, L; Lustermann, W; Ma Wen Gan; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mans, J; Martin, J P; Marzano, F; Mazumdar, K; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Mihul, A; Milcent, H; Mirabelli, G; Mnich, J; Mohanty, G B; Muanza, G S; Muijs, A J M; Musicar, B; Musy, M; Nagy, S; Natale, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nisati, A; Nowak, H; Ofierzynski, R A; Organtini, G; Palomares, C; Pandoulas, D; Paolucci, P; Paramatti, R; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Pedace, M; Pensotti, S; Perret-Gallix, D; Petersen, B; Piccolo, D; Pierella, F; Pioppi, M; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; Pothier, J; Prokofiev, D O; Prokofev, D; Quartieri, J; Rahal-Callot, G; Rahaman, M A; Raics, P; Raja, N; Ramelli, R; Rancoita, P G; Ranieri, R; Raspereza, A V; Razis, P A; Ren, D; Rescigno, M; Reucroft, S; Riemann, S; Riles, K; Roe, B P; Romero, L; Rosca, A; Rosier-Lees, S; Roth, S; Rosenbleck, C; Roux, B; Rubio, Juan Antonio; Ruggiero, G; Rykaczewski, H; Sakharov, A; Saremi, S; Sarkar, S; Salicio, J; Sánchez, E; Sanders, M P; Schäfer, C; Shchegelskii, V; Schmidt-Kärst, S; Schmitz, D; Schopper, Herwig Franz; Schotanus, D J; Schwering, G; Sciacca, C; Servoli, L; Shevchenko, S; Shivarov, N; Shoutko, V; Shumilov, E; Shvorob, A V; Siedenburg, T; Son, D; Spillantini, P; Steuer, M; Stickland, D P; Stoyanov, B; Strässner, A; Sudhakar, K; Sultanov, G G; Sun, L Z; Sushkov, S V; Suter, H; Swain, J D; Szillási, Z; Tang, X W; Tarjan, P; Tauscher, Ludwig; Taylor, L; Tellili, B; Teyssier, D; Timmermans, C; Ting, Samuel C C; Ting, S M; Tonwar, S C; Tóth, J; Tully, C; Tung, K L; Ulbricht, J; Valente, E; Van de Walle, R T; Veszpremi, V; Vesztergombi, G; Vetlitskii, I; Vicinanza, D; Viertel, Gert M; Villa, S; Vivargent, M; Vlachos, S; Vodopyanov, I; Vogel, H; Vogt, H; Vorobev, I; Vorobyov, A A; Wadhwa, M; Wallraff, W; Wang, X L; Wang, Z M; Weber, M; Wienemann, P; Wilkens, H; Wynhoff, S; Xia, L; Xu, Z Z; Yamamoto, J; Yang, B Z; Yang, C G; Yang, H J; Yang, M; Yeh, S C; Zalite, A; Zalite, Yu; Zhang, Z P; Zhao, J; Zhu, G Y; Zhu, R Y; Zhuang, H L; Zichichi, A; Zilizi, G; Zimmermann, B; Zöller, M

    2002-01-01

    The process e+ e- -> n gamma with n>=2 is studied at centre-of-mass energies ranging from \\root(s)=192 to 208 GeV. The data sample corresponds to a total integrated luminosity of 427 1/pb. The total and differential cross sections are found to be in agreement with the QED expectations. Using all the data collected with the L3 detector above the Z pole, limits on deviations from QED, excited electrons, contact interactions, extra space dimensions and excited spin-3/2 leptons are set.

  3. NHEXAS PHASE I REGION 5 STUDY--STANDARD OPERATING PROCEDURE--NHEXAS PILOT FIELD STUDY SCRIPTING AND LOGISTICS (RTI/ACS-AP-209-080)

    Science.gov (United States)

    This protocol provides an overview of the schedule, scripting, and logistics for home visits conducted in the NHEXAS Region 5 study. By its nature, this protocol provides a general description of these activities, since the actual schedule was subject to change due to outside cir...

  4. Two organophosphorus flame retardants, resorcinol bis (diphenylphosphate)(PBDPP) and bisphenol A bis (diphenylphosphate) (BPA-BDPP) used as alternatives for BDE209 detected in dust

    OpenAIRE

    Brandsma, Sicco H.; Sellström, Ulla; de Wit, Cynthia A.; de Boer, Jacob; Leonards, Pim E.G.

    2013-01-01

    Resorcinol bis(diphenylphosphate) (RBDPP) and bisphenol A bis(diphenylphosphate) (BPA-BDPP) are two halogen-free organophosphorus flame retardant (PFRs) that are used as an alternative for the decabromodiphenyl ether (Deca-BDE) technical mixture in TV/flatscreen housing and other electronic consumer products.' In this study, dust samples were collected from various microenvironments in The Netherlands (houses, cars), Greece.(houses), and Sweden (apartments, cars, furniture stores, electronics...

  5. Evidence of social and environmental vulnerability in Sepetiba Bay: an analysis of risk situations - doi:10.5020/18061230.2009.p209

    Directory of Open Access Journals (Sweden)

    Aldo Pacheco Ferreira

    2012-01-01

    Full Text Available Objective: To identify, among the population of Sepetiba Bay, risk situations of environmental vulnerability. Methods: Data collection was performed through a self-administered questionnaire with open and closed questions in a determined population of 895 subjects, between 2007 and 2009. The techniques used consisted of semi-structured interviews, structured questionnaires and participant observation (triangulation of methods. After the validation of the instrument by stages (face validity, content validity and construct validity,the main risks reported by the subjects were determined. Results: A total of 675 environmental risk situations was detected, especially the contamination of the water, soil and air; the waste; the impact on flora and social demands. It was observed that the same risk may simultaneously affect more than one location, emphasizing that one same problem was mentioned in more than one location of the bay. Conclusions: The results support the hypothesis guiding the research that the environment is part of the culture of a particular community or group as a process of interaction between cultural and natural environment.

  6. Nuclear Level Density Parameters of Pb203-209 and Bi206-210 Deformed Target Isotopes Used on Accelerator-Driven Systems in Collective Excitation Modes

    Directory of Open Access Journals (Sweden)

    Şeref Okuducu

    2012-01-01

    Full Text Available The nuclear level density parameters of some deformed isotopes of target nuclei (Pb, Bi used on the accelerator-driven subcritical systems (ADSs have been calculated taking into consideration different collective excitation modes of observed nuclear spectra near the neutron binding energy. The method used in the present work assumes equidistant spacing of the collective coupled state bands of the considered isotopes. The present calculated results for different collective excitation bands have been compared with the compiled values from the literature for s-wave neutron resonance data, and good agreement was found.

  7. A study of shell model neutron states in 207,209Pb using the generalized Woods-Saxon plus spin-orbit potential

    Science.gov (United States)

    Liendo, J. A.; Castro, E.; Gómez, R.; Caussyn, D. D.

    2016-07-01

    The experimental binding energies of single-particle and single-hole neutron states belonging to neutron shells that extend from N = 126-184 and 82-126, respectively, have been reproduced by solving the Schrödinger equation with a potential that has two components: the generalized Woods-Saxon (GWS) potential and the spin-orbit (SO) coupling term. The GWS potential contains the traditional WS potential plus a term (SU) whose intensity reaches a maximum in the nuclear surface. Our results indicate the existence of an explicit relationship between the strength of the SU potential and the orbital angular momentum quantum number ℓ of the state. This dependence has been used to make reasonable predictions for the excitation energy centroids of states located inside and outside the neutron shells investigated. Comparisons are made with results reported in previous investigations.

  8. Correlations between Polarisation States of W Particles in the Reaction $e^- e^+\\to W^- W^+$ at LEP2 Energies 189-209 GeV

    CERN Document Server

    Abdallah, J; Adam, W; Adzic, P; Albrecht, T; Alemany-Fernandez, R; Allmendinger, T; Allport, P P; Amaldi, U; Amapane, N; Amato, S; Anashkin, E; Andreazza, A; Andringa, S; Anjos, N; Antilogus, P; Apel, W-D; Arnoud, Y; Ask, S; Åsman, B; Augustin, J E; Augustinus, A; Baillon, P; Ballestrero, A; Bambade, P; Barbier, R; Bardin, D; Barker, G J; Baroncelli, A; Battaglia, M; Baubillier, M; Becks, K-H; Begalli, M; Behrmann, A; Ben-Haim, E; Benekos, N; Benvenuti, A; Bérat, C; Berggren, M; Bertrand, D; Besançon, M; Besson, N; Bloch, D; Blom, M; Bluj, M; Bonesini, M; Boonekamp, M; Booth, P S L; Borisov, G; Botner, O; Bouquet, B; Bowcock, T J V; Boyko, I; Bracko, M; Brenner, R; Brodet, E; Brückman, P; Brunet, J M; Buschbeck, B; Buschmann, P; Calvi, M; Camporesi, T; Canale, V; Carena, F; Castro, N; Cavallo, F; Chapkin, M; Charpentier, Ph; Checchia, P; Chierici, R; Chliapnikov, P V; Chudoba, J; Chung, S U; Cieslik, K; Collins, P; Contri, R; Cosme, G; Cossutti, F; Costa, M J; Crennell, D J; Cuevas-Maestro, J; D'Hondt, J; Da Silva, T; Da Silva, W; Della Ricca, G; De Angelis, A; de Boer, Wim; De Clercq, C; De Lotto, B; De Maria, N; De Min, A; De Paula, L; Di Ciaccio, L; Di Simone, A; Doroba, K; Drees, J; Eigen, G; Ekelöf, T J C; Ellert, M; Elsing, M; Espirito-Santo, M C; Fanourakis, G K; Fassouliotis, D; Feindt, M; Fernández, J; Ferrer, A; Ferro, F; Flagmeyer, U; Föth, H; Fokitis, E; Fulda-Quenzer, F; Fuster, J; Gandelman, M; García, C; Gavillet, Ph; Gazis, E; Gokieli, R; Golob, B; Gómez-Ceballos, G; Gonçalves, P; Graziani, E; Grosdidier, G; Grzelak, K; Guy, J; Haag, C; Hallgren, A; Hamacher, K; Hamilton, K; Haug, S; Hauler, F; Hedberg, V; Hennecke, M; Hoffman, J; Holmgren, S-O; Holt, P J; Houlden, M A; Jackson, J N; Jarlskog, G; Jarry, P; Jeans, D; Johansson, E K; Jonsson, P; Joram, C; Jungermann, L; Kapusta, F; Katsanevas, S; Katsoufis, E; Kernel, G; Kersevan, B P; Kerzel, U; King, B T; Kjaer, N J; Kluit, P; Kokkinias, P; Kourkoumelis, C; Kuznetsov, O; Krumshtein, Z; Kucharczyk, M; Lamsa, J; Leder, G; Ledroit, F; Leinonen, L; Leitner, R; Lemonne, J; Lepeltier, V; Lesiak, T; Liebig, W; Liko, D; Lipniacka, A; Lopes, J H; López, J M; Loukas, D; Lutz, P; Lyons, L; MacNaughton, J; Malek, A; Maltezos, S; Mandl, F; Marco, J; Marco, R; Maréchal, B; Margoni, M; Marin, J-C; Mariotti, C; Markou, A; Martínez-Rivero, C; Masik, J; Mastroyiannopoulos, N; Matorras, F; Matteuzzi, C; Mazzucato, F; Mazzucato, M; McNulty, R; Meroni, C; Migliore, E; Mitaroff, W A; Mjörnmark, U; Moa, T; Moch, M; Mönig, K; Monge, R; Montenegro, J; Moraes, D; Moreno, S; Morettini, P; Müller, U; Münich, K; Mulders, M; Mundim, L; Murray, W; Muryn, B; Myatt, G; Myklebust, T; Nassiakou, M; Navarria, F; Nawrocki, K; Némécek, S; Nicolaidou, R; Nikolenko, M; Oblakowska-Mucha, A; Obraztsov, V F; Olshevski, A; Onofre, A; Orava, R; Österberg, K; Ouraou, A; Oyanguren, A; Paganoni, M; Paiano, S; Palacios, J P; Palka, H; Papadopoulou, Th D; Pape, L; Parkes, C; Parodi, F; Parzefall, U; Passeri, A; Passon, O; Peralta, L; Perepelitsa, V; Perrotta, A; Petrolini, A; Piedra, J; Pieri, L; Pierre, F; Pimenta, M; Piotto, E; Podobnik, T; Poireau, V; Pol, M E; Polok, G; Pozdnyakov, V; Pukhaeva, N; Pullia, A; Radojicic, D; Rebecchi, P; Rehn, J; Reid, D; Reinhardt, R; Renton, P B; Richard, F; Rídky, J; Rivero, M; Rodríguez, D; Romero, A; Ronchese, P; Roudeau, P; Rovelli, T; Ruhlmann-Kleider, V; Ryabtchikov, D; Sadovskii, A; Salmi, L; Salt, J; Sander, C; Savoy-Navarro, A; Schwickerath, U; Sekulin, R; Siebel, M; Sisakian, A; Smadja, G; Smirnova, O; Sokolov, A; Sopczak, A; Sosnowski, R; Spassoff, Tz; Stanitzki, M; Stocchi, A; Strauss, J; Stugu, B; Szczekowski, M; Szeptycka, M; Szumlak, T; Tabarelli de Fatis, T; Tegenfeldt, F; Timmermans, J; Tkatchev, L; Tobin, M; Todorovova, S; Tomé, B; Tonazzo, A; Tortosa, P; Travnicek, P; Treille, D; Tristram, G; Trochimczuk, M; Troncon, C; Turluer, M-L; Tyapkin, I A; Tyapkin, P; Tzamarias, S; Uvarov, V; Valenti, G; van Dam, P; Van Eldik, J; Van Remortel, N; Van Vulpen, I; Vegni, G; Veloso, F; Venus, W; Verdier, P; Verzi, V; Vilanova, D; Vitale, L; Vrba, V; Wahlen, H; Washbrook, A J; Weiser, C; Wicke, D; Wickens, J; Wilkinson, G; Winter, M; Witek, M; Yushchenko, O; Zalewska-Bak, A; Zalewski, P; Zavrtanik, D; Zhuravlov, V; Zimin, N I; Zintchenko, A; Zupan, M

    2009-01-01

    In a study of the reaction e-e+ -> W-W+ with the DELPHI detector, the probabilities of the two W particles occurring in the joint polarisation states transverse-transverse (TT), longitudinal-transverse plus transverse-longitudinal (LT) and longitudinal-longitudinal (LL) have been determined using the final states WW -> l nu q qbar (l = e, mu). The two-particle joint polarisation probabilities, i.e. the spin density matrix elements rho_TT, rho_LT, rho_LL, are measured as functions of the W- production angle, theta_W-, at an average reaction energy of 198.2 GeV. Averaged over all cos(theta_W-), the following joint probabilities are obtained: rho_TT = (67 +/- 8)%, rho_LT = (30 +/- 8)%, rho_LL = (3 +/- 7)% . These results are in agreement with the Standard Model predictions of 63.0%, 28.9% and 8.1%, respectively. The related polarisation cross-sections sigma_TT, sigma_LT and sigma_LL are also presented.

  9. Rendimento de óleo essencial de Salvia officinalis L. sob ação de reguladores vegetais - DOI: 10.4025/actascibiolsci.v28i3.209 Essential oil yield in Salvia officinallis L. under the action of plant growth regulators - DOI: 10.4025/actascibiolsci.v28i3.209

    Directory of Open Access Journals (Sweden)

    Elizabeth Orika Ono

    2007-11-01

    Full Text Available O objetivo deste trabalho foi avaliar o efeito de diferentes reguladores vegetais no rendimento do óleo essencial de plantas de Salvia officinalis L. O experimento foi conduzido em casa de vegetação e o delineamento experimental foi inteiramente casualizado, consistindo em cinco tratamentos com três repetições cada. Os tratamentos consistiram na aplicação de ácido giberélico (GA3, benzilaminopurina (BAP e ácido 2- cloroetil-fosfônico (ethephon e Stimulate a 2%, comparados com plantas controle (água. A pulverização, via foliar, dos reguladores vegetais foram realizadas em três épocas, aos 15, 25 e 35 dias após o transplante de plântulas previamente germinadas em câmaras de germinação a 25ºC e luz constante. A produção de massa seca da parte aérea e rendimento do óleo essencial foi avaliada aos 131 dias após o transplante. A parte aérea das plantas foi seca em estufa a 35ºC determinando a massa seca e a extração do óleo foi realizada pelo método de hidrodestilação, determinando o volume de óleo. Plantas tratadas com GA3 e Stimulate apresentaram incrementos no teor de óleo essencial, enquanto que as plantas tratadas com BAP e ethephon apresentaram diminuição no volume de óleo essencial comparado às plantas controle.This study aimed to evaluate the effect of different plant growth regulators on essential oil yield in Salvia officinalis L. plants. The experiment was held in a greenhouse and the experimental design was completely randomized, with 5 treatments and three replications. The Treatments consisted in the application of gibberellic acid (GA3, benzylaminopurine (BAP, 2-chloroethyl phosphonic acid (ethephon, and Stimulate at 2%, compared with control plants (water. Applications of plant growth regulators were performed in three consecutive periods, in turn, 15, 25 and 35 days after transplanting of seeding germinating in the light at 25ºC. The dry mass yield of the aerial part and the oil essential content were determined 131 days after the transplant. The aerial part of the plants was dried in an oven at 35ºC; after dry mass determination, the oil was extracted by hydrodistillation and its volume was determined. Plants treated with GA3 and Stimulate showed increase in essential oil content, while plants treated with BAP and ethephon showed decrease in essential oil volume when compared with the control plants.

  10. SPECT assay of radiolabeled monoclonal antibodies. Final performance report, March 1992--November 1995

    Energy Technology Data Exchange (ETDEWEB)

    Jaszczak, R.J.

    1995-12-01

    Research is described in the following areas: development and evaluation quantitatively of reconstruction algorithms with improved compensations for attenuation, scatter, and geometric collimator response; evaluation of single photon emission computed tomography (SPECT) quantification of iodine 123 and astatine 211; and the development and evaluation of SPECT pinhole imaging for low and medium energy photons.

  11. Shelf-life of ɛ-lysyl-3-(trimethylstannyl)benzamide immunoconjugates, precursors for 211At labeling of antibodies

    DEFF Research Database (Denmark)

    Aneheim, Emma; Halleröd, Jenny; Albertsson, Per;

    2015-01-01

    Astatine-211 is possibly the most promising radionuclide for targeted α-particle therapy when it comes to the treatment of occult disseminated cancer. Preclinical research has proven effective, and patient studies have been initiated based on these results. However, a lack of production capacity...

  12. 10 CFR Appendix B to Part 20 - Annual Limits on Intake (ALIs) and Derived Air Concentrations (DACs) of Radionuclides for...

    Science.gov (United States)

    2010-01-01

    .... Actinium Ac 89 Aluminum Al 13 Americium Am 95 Antimony Sb 51 Argon Ar 18 Arsenic As 33 Astatine At 85... Curium Cm 96 Dysprosium Dy 66 Einsteinium Es 99 Erbium Er 68 Europium Eu 63 Fermium Fm 100 Fluorine F...

  13. SPECT assay of radiolabeled monoclonal antibodies. Final performance report, March 1992--November 1995

    International Nuclear Information System (INIS)

    Research is described in the following areas: development and evaluation quantitatively of reconstruction algorithms with improved compensations for attenuation, scatter, and geometric collimator response; evaluation of single photon emission computed tomography (SPECT) quantification of iodine 123 and astatine 211; and the development and evaluation of SPECT pinhole imaging for low and medium energy photons

  14. Hurdles for a Broader Use of 211At and for the Synthesis of 211At-Labelled Radiopharmaceuticals at High Activities for Clinical Use

    International Nuclear Information System (INIS)

    One of the key impediments to the use of 211At is the very well known deleterious effect of high radiation fields caused by its alpha particles on the synthesis of 211At-labelled radiopharmaceuticals. This is problematic because radiolysis-mediated effects can produce diminishing efficiency of electrophilic astatination reactions due to increasing deposition of radiation dose with increasing activities and with the passage of the time. Astatine-211 has chemical properties that permit complex labelling strategies and a longer half-life than 213Bi that makes it more suitable when the targeting molecule does not gain immediate access to the tumour cells. The first clinical evaluation was published in 2001 [2] in patients with brain tumour. Although this study circumvents many of the challenges to entering clinical studies with 211At and many obstacles had to be surmounted before clinical studies could be initiated, several problems were encountered in maintaining efficient labelling with escalating radiation dose of α-particle even with fresh 211At elution [3]. Astatine-211 also has an additional hurdle to overcome before to its clinical application in labelled radiopharmaceuticals related with its production and distribution. Among the potential group of promising α- emitter it is the only one produced by cyclotrons, but due to the scarcity of cyclotrons equipped with 25−30 MeV α-particle beams, it will of necessity be utilized in distant locations from the site of production. It presents a major chemical challenge because the diminishing efficiency of electrophilic astatination reactions with the passage of the time is well known, a problem likely related to the radiolysis produced by the high LET (linear energy transfer) meaning that large amounts of energy are deposited in a highly localized manner. This problem has been most comprehensively investigated to understand and evaluate the role of the radiolysis effects of astatine alpha particles in the synthesis

  15. Iceland and mid-ocean ridges : S. Björnsson (editor). Vísindafélag Islendinga, Reykjavik, 1967, 209 pp., 65 illus., U.S. $8.50

    NARCIS (Netherlands)

    Rutten, M.G.

    1968-01-01

    Although the quality of the papers is high and the insights obtained are rewarding and modern, I should have still preferred the inclusion of some more factual data. For instance, in Gudmundur Sigwaldason’s paper on the chemistry of basalts, the 43 analyses known are promised, but not produced. In K

  16. Study on preservatives of vacuum-packed Chinese New Year rice cake . Journal of Zhejiang University (Agric . & Life Sci .), 2013,39(2):209-214%真空包装年糕保鲜剂研究

    Institute of Scientific and Technical Information of China (English)

    张希; 何逸波; 杜鹃; 冯凤琴

    2013-01-01

    Summary Water milled Chinese New Year rice cake ( NYRC ) is a kind of delicious and nutritive Chinese traditional food . But the short shelf life of the NYRC restricts its industrialization development . The purpose of the study is to inhibit the growth of spoilage microorganisms effectively and to extend the shelf life of the vacuum‐packed NYRC . There were four main steps:1) the spoilage microorganisms were separated and characterized from vacuum‐packed NYRC . 2) Six commonly used antibacterial agents were chosen against the spoilage microorganisms , and the minimum inhibitory concentrations ( MIC ) were determined . 3 ) The synergistic effects between glycerol monolaurate ( GML) and other preservatives were measured . 4) In order to investigate application effect of chosen food preservatives , lab and factory testes were taken in NYRC product . The moisture , hardness and colour ( L value) of the vacuum‐packed NYRC were determined . The main results were as follows:1) The spoilage microorganisms which led to corruption of vacuum‐packed NYRC were two kinds of Bacillus . 2) Among the tested preservatives , GML had the lowest MIC which was 32μg/mL . 3 ) There was synergistic effect of GML and sodium dehydroacetate , and the fractional inhibitory concentration index ( FIC I ) was 0 .531 . The compound preservative made up of GML , citric acid and sodium dehydroacetate at the mass ratio of 1∶1∶1 was selected against the Bacillus . 4) Adding the selected compound preservative of 1 .5g/kg could extend the shelf life from about 7 d to 20 d at 37 ℃ . The compound preservative not only had no adverse effect on the moisture and color of NYRC , but also could reduce the hardness efficiently . In NYRC products , the compound preservative shows significantly better effect than the monomer GML . In addition , while prolonging the shelf life of the vacuum‐packed NYRC , the compound preservative had no adverse effect on its quality .%  为了有效地抑制真空包装水磨年糕腐败微生物的生长,延长其保质期,首先分离并鉴定真空包装年糕中的腐败微生物;针对该菌种选取相应的保鲜剂,并通过测定单体和复配保鲜剂的最低抑制质量浓度和协同增效作用,确定适用于真空包装年糕的复配保鲜剂.结果表明:导致真空包装年糕腐败的微生物主要为芽孢杆菌属( Bacillus);针对该类微生物的适宜复配保鲜剂配方为 w(单甘油月桂酸酯)∶ w(柠檬酸)∶ w(脱氢醋酸钠)=1∶1∶1;经过实验室和工厂大试检测表明,添加1.5 g/kg该复配物,同时在95℃灭菌60 min ,能将真空包装水磨年糕的保质期由原来在37℃下7 d左右提高到20 d .说明用该配方不仅能有效地延长年糕的保质期,且其品质不会受到影响;单甘油月桂酸酯还可降低年糕的硬度.

  17. Maternal glycated haemoglobin, pre-gestational weight, pregnancy weight gain and risk of large-for-gestational-age babies: a Danish cohort study of 209 singleton Type 1 diabetic pregnacies

    DEFF Research Database (Denmark)

    Nielsen, G.L.; Dethlefsen, Claus; Møller, M.;

    2007-01-01

    Aims To examine the association between maternal glycated haemoglobin in the second half of diabetic pregnancies and the relative risk of delivering large-for-gestational-age (LGA) babies, controlling for maternal body mass index (BMI) before pregnancy, weight gain, age, White class and smoking...... habits. Methods We identified all pregnant diabetic women in North Jutland County, Denmark from 1985 to 2003. Data on HbA1c values from the 20th gestational week to term were collected from medical records and the babies were classified as large, normal or small for gestational age. The association...

  18. Multibeam collection for KN209-01: Multibeam data collected aboard Knorr from 2012-09-06 to 2012-10-09, departing from Woods Hole, MA and returning to Ponta Delgada, Azores

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  19. Multibeam collection for KN209-02: Multibeam data collected aboard Knorr from 2012-10-16 to 2012-11-09, departing from Ponta Delgada, Azores and returning to Charleston, SC

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This data set is part of a larger set of data called the Multibeam Bathymetry Database (MBBDB) where other similar data can be found at...

  20. Information Literacy Programs and Research: Reflections on "Information Literacy Programs and Research: An International Review" by Christine Bruce. 2000. "The Australian Library Journal" 49 no. 3: 209-218.

    Science.gov (United States)

    Bruce, Christine

    2011-01-01

    Although in the late 1990s there was much discussion as to whether the idea of information literacy was necessary or had longevity, global interest in the phenomenon has increased rather than diminished. Information literacy standards have been developed and become widely accepted in educational systems. Research centres for information literacy…

  1. $\\beta$-delayed fission, laser spectroscopy and shape-coexistence studies with radioactive At beams

    CERN Multimedia

    We propose to study the $\\beta$-delayed fission, laser spectroscopy and radioactive decay of the newly available pure beams of neutron-deficient and neutron-rich astatine (Z=85) isotopes. The fission probability and the fission fragment distribution of the even-even isotopes $^{194,196}$Po following the $\\beta$-decay of the isotopes $^{194,196}$At will be studied with the Windmill setup. In-source laser spectroscopy will be performed on the entire astatine isotopic chain, using a combination of the Windmill setup, ISOLTRAP MR-ToF and ISOLDE Faraday. Radioactive decay data will be acquired at the Windmill setup throughout those studies and contribute to the global understanding of the phenomenon of shape coexistence in the neutron-deficient lead region.

  2. 209株临床分离的不同基因型白假丝酵母菌和丝状真菌的抗真菌药物敏感性及其耐药性趋势研究%Study on antifungal susceptibilities and resistance trends of 209 strains of C.albicans with various genotypes and filamentous fungi isolated from clinical specimens

    Institute of Scientific and Technical Information of China (English)

    王和; 康颖倩; 刘姝; 罗振华; 王丹霓

    2012-01-01

    目的 了解常见致病性真菌的药物敏感性及其耐药性趋势.方法 检测临床分离白假丝酵母菌和丝状菌的抗真菌药物敏感性.结果 176株白假丝酵母菌A型(55.1%)、B型(29.0%)和C型(15.9%)的FC和AP敏感率较高(88.7%~100%),FL、IT及VR 敏感率较低(小于26%).各基因型菌株在FC、AP、FL、IT、VR敏感性无明显差异(P>0.05),在FC与AP、FL、IT、VR,AP与FL、IT、VR之间存在显著的敏感率差异(P<0.001).33株丝状菌的MIC值,9株(27.3%)AP≥3μg/mL,7株(21.2 %)FC≥3μg/mL,32株(97%)FL>256μg/mL.各菌株的FC、AP、FL、IT、CS敏感率有差异,AP与FL、CS,IT与FL、CS,FC与FL、CS,FL与CS之间的敏感率差异显著(P<0.001).结论 白假丝酵母菌基因A型、B型和C型对所测试抗真菌药物的敏感性无明显差异.白假丝酵母菌和丝状菌多数菌株表现出较高的耐药率和明显的耐药性发展趋势.%Objective To investigate the antifungal susceptibilities and resistance trends of the pathogenic fungi. Methods With the method of minimum inhibitory concentration (MIC) test, the susceptibilities and the trend of drug-resistance to flucytosine, amphotericin B, fluconazole, itraconazole, voriconazole and/or caspofungin of 176 strains of C. albicans and 33 filamentous fungi which were isolated from patients with infectious diseases were detected. Results 176 strains of C. albicans, including 97 strains of genotype A (55.1%), 51 strains of genotype B (29.0%) and 28 strains of genotype C (15.9%), were sensitive to flucytosine and amphotericin B (sensitivity rate of 88.7% to 100%) but resistant to fluconazole, itraconazole and voriconazole (sensitivity rate<26%=. In various genotypes of C. albicans, no significant difference in susceptibility rates of flucytosine, amphotericin B, fluconazole, itraconazole, voriconazole can be found (P>0.05). However, the significant difference (P<0.001= in susceptibility rates of different antifungal drugs can be observed between flucytosine and other drugs such as amphotericin B, fluconazole, itraconazole and voriconazole; such difference can be also observed between amphotericin B and azole group. In 33 filamentous fungi, MIC values of amphotericin B for 9 strains (27.3%) were≥3μg/mL, flucytosine for 7 strains (27.3%) were≥3μg/mL, and fluconazole for 32 strains (97%) were≥256μg/mL, respectively. The susceptibility differences for the strains existed in flucytosine, amphotericin B, fluconazole, itraconazole and caspofiingin. Among them, the significant differences (P<0.001) in susceptibility rates of these strains can be observed between amphotericin B and fluconazole/caspofungin, between itraconazole and fluconazole/caspofungin, between flucytosine and fluconazole/ caspofungin, and between fluconazole and caspofungin, respectively. Conclusion There is no significant differences existed in the drug susceptibility test for the C. albicans strains with different genotypes A, B and C. Most strains of C. albicans and filamentous fungi displayed the resistance characteristics and showed the resistance tendency to antifungal drugs.

  3. Radiopharmaceutical Chemistry of Targeted Radiopharmaceutics. Synthesis of 211At-Labeled Radiopharmaceuticals at High Activities for Clinical Use

    International Nuclear Information System (INIS)

    Targeted α-particle radiotherapy is an appealing approach to cancer treatment because of the potential for delivering curative doses of radiation to tumor with minimal damage to normal tissue due to a range equivalent to only a few cell diameters. Compared with β-emitters they have significant advantages from a radiobiological perspective. The LET of 211At α-particles is more than 400 times higher than the β-particles emitted by 90Y, in addition the distance between ionizing events is almost the same as that between the two strands of DNA, yielding a high probability of creating non-repairable DNA damage. It gives the ability to kill cancer cells not compromised by hypoxia, dose rate effects or cell cycle position, enhancing their attractiveness for targeted radiotherapy. However, translation of the concept to the clinic has been slow, many obstacles had to be surmounted before clinical studies could be initiated, the first clinical evaluation of a 211At- labeled mAb was made in 2001. This study circumvents many of the challenges to entering clinical studies with 211At. But several problems were encountered in maintaining efficient labeling with escalating radiation dose of alpha-particle likely related to radiolysis. The impact of the radiolysis produced by the α-particle over the labeling chemistry is much higher in comparison with typical β-emitters due to a deposition of energy in the solvent in a highly localized manner two orders of magnitude per unit volume higher than 90Y or 131I. Due to these difficulties a comprehensive basic science study about the radiolytic effects of astatine alpha-particles over the synthesis of 211At-labeled radiopharmaceuticals was carried out. Its main goal was overcoming the problem of the synthesis of 211At-labeled radiopharmaceuticals at the high activities necessaries for therapy and also to extend the shelf life of astatine elutions. Briefly this study held several steps, the first one was to study the role of solvent

  4. 32 CFR 516.65 - Litigation reports in civil recovery cases.

    Science.gov (United States)

    2010-07-01

    ... CIVIL AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.65... prepared on a given case such as the DFARS 209.406-3 (48 CFR 209.406-3) report. (d) The MACOM...

  5. Main: 1MVL [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1MVL シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Phosphopantothenoylcystei...6641; BAB01331.1; -.|PDB; 1E20; X-ray; A=1-209.|PDB; 1MVL; X-ray; A=1-209.|PDB; 1MVN; X-ray; A=1-209.|InterP...LCDNLLTCIIRAWDYTKPLFVAPAMNTLMWNNPFTERHLLSLDELGITLIPPIKKRLACGDYGNGAMAEPSLIYSTVRLFWESQAHQQTGGTS arabi_1MVL.jpg ...

  6. 76 FR 71922 - Defense Federal Acquisition Regulation Supplement: Separation of Combined Provisions and Clauses...

    Science.gov (United States)

    2011-11-21

    .... * * * * * (ii) 252.209-7002, Disclosure of Ownership or Control by a Foreign Government. (iii) 252.209-7003...) 252.209-7001, Disclosure of Ownership or Control by the Government of a Terrorist Country. Applies to... part in a foreign country; and (B) A foreign government controls wage rates or material prices and...

  7. Molecular and Biological Characterization of an Isolate of Cucumber mosaic virus from Glycine soja by Generating its Infectious Full-genome cDNA Clones

    Directory of Open Access Journals (Sweden)

    Mi Sa Vo Phan

    2014-06-01

    Full Text Available Molecular and biological characteristics of an isolate of Cucumber mosaic virus (CMV from Glycine soja (wild soybean, named as CMV-209, was examined in this study. Comparison of nucleotide sequences and phylogenetic analyses of CMV-209 with the other CMV strains revealed that CMV-209 belonged to CMV subgroup I. However, CMV-209 showed some genetic distance from the CMV strains assigned to subgroup IA or subgroup IB. Infectious full-genome cDNA clones of CMV-209 were generated under the control of the Cauliflower mosaic virus 35S promoter. Infectivity of the CMV-209 clones was evaluated in Nicotiana benthamiana and various legume species. Our assays revealed that CMV-209 could systemically infect Glycine soja (wild soybean and Pisum sativum (pea as well as N. benthamiana, but not the other legume species.

  8. Human radiation studies: Remembering the early years: Oral history of Dr. Patricia Wallace Durbin, Ph.D., conducted November 11, 1994

    International Nuclear Information System (INIS)

    This report is a transcript of an interview of Dr. Patricia Wallace Durbin by representatives of the US DOE Office of Human Radiation Research. Dr. Durbin was selected for this interview because of her knowledge of the human plutonium injections and her recollections of key figures, especially Joseph Hamilton. After a brief biographical sketch Dr. Durbin discusses her loss of research funding from DOE, her recollections concerning research into strontium metabolism as part of Project Sunshine, her recollections relating to the rationale for studies of human metabolism of radionuclides, her remembrances of Dr. Hamilton's Astatine and Plutonium research, and her experiences in gathering archival records concerning these researches

  9. EFFECT OF MECHANICAL PROPERTIES OF MARTENSITE AND LOADING RATE ON DUAL PHASE STEELS

    OpenAIRE

    BAYRAM, Ali

    1998-01-01

    In this study, steel sheet materials were used in order to obtain dual-phase steel. Specimens for this purpose have been annealed in ferrite + astatine regions at the temperatures of 740, 760, 800 and 820 °C. The specimens were annealed at the different temperatures with corresponding times 20, 40 and 60 minutes and quenched into water. As a result of this dual-phase steels at different ferrite + martensite ratio were produced. Sheet specimens were tested at the range of loading rates of 1...

  10. 76 FR 79203 - Prospective Grant of Exclusive License: Veterinary Biological Products for Swine Influenza Vaccines

    Science.gov (United States)

    2011-12-21

    ..., HHS. ACTION: Notice. SUMMARY: This is notice, in accordance with 35 U.S.C. 209(c)(1) and 37 CFR 404.7... and will comply with the terms and conditions of 35 U.S.C. 209 and 37 CFR 404.7. The prospective... consistent with the requirements of 35 U.S.C. 209 and 37 CFR 404.7. The invention relates to compositions...

  11. Cause analysis on sidewall enclosure superheater tube rupture of 2 209 t/h boiler in Huaneng Dezhou Power Plant%华能德州电厂2209t/h锅炉侧墙包复过热器爆管原因分析

    Institute of Scientific and Technical Information of China (English)

    黄新元; 刘长振; 张凯; 马东森

    2004-01-01

    建立了计算华能德州电厂2209t/h锅炉侧墙包复过热器流量偏差的数学模型,指出该炉频繁爆管的根本原因在于侧墙包复过热器存在固定的滞流区域.利用本模型对增加的管子入口节流圈的流量分布进行估计,采取相应措施后解决了该炉的爆管问题.

  12. Communication Breakdown: Librarian and Student Approaches to Virtual Reference Differ. A review of: Walter, Virginia A. and Cindy Mediavilla. “Teens Are from Neptune, Librarians Are from Pluto: An Analysis of Online Reference Transactions.” Library Trends 54.2 (2005: 209-227.

    Directory of Open Access Journals (Sweden)

    Stephanie Hall

    2006-09-01

    Full Text Available Objective – To evaluate the effectiveness of an online reference and referral service for students (primarily those in middle school and high school seeking homework help. Design – Analysis of 114 transcripts of reference transactions. Setting – A centralized homework reference and tutor referral service provided on behalf of the California State Library by the Metropolitan Cooperative Library System. Subjects – Virtual reference librarians at a large urban library system and middle and high school students in California. Methods – One hundred fourteen virtual reference transactions recorded between October 12 and November 8, 2003 were evaluated against the Reference and User Services Association’s (RUSA “Guidelines for Behavioral Performance of Reference and Information Service Providers.” Secondly, the transcripts were subjected to discourse analysis. Main results Performance of virtual reference librarians vis‐àvis RUSA guidelines In the majority of cases, there was some evidence that librarians communicated clearly (110 out of 114 transactions. In 78 cases, it appeared that a librarian was available quickly, and in 92 of the transactions a friendly greeting was given. What was striking, however, was that in a clear majority of cases, some of the classic reference interview strategies were not employed. In 100 or more cases each, the following strategies were not observed: repeating or paraphrasing the question; helping to interpret the question; verifying mutual understanding; asking if the question has been answered; asking if the student needs more information. Furthermore, in 75 cases librarians did not probe for further information to clarify the question, while in 87 cases they did not check that information had been clearly understood. Possibly related to these findings, the researchers felt that the transcripts revealed “a conviction that homework questions are not the proper content for reference transactions” (222. In addition, librarians were found to be frequently too quick to refer students to a tutor, when a query might have been better answered as a reference question. Findings of discourse analysis In general, the virtual reference librarians used impersonal, formal language to “reinforce the professional’s superior position vis‐à‐vis the help‐seeker” (217. There were repeated attempts by the students to interject a lighter or warmer tone (using humour, emoticons, informal language, introducing a personal note, etc.. These attempts were rarely reciprocated, with librarians continuing to use impersonal language, including stock messages such as: “we are experiencing a very busy time right now,” (217; or, “I am going to send you a page which will give you some help with your homework. After we disconnect this session, click on this link and follow the instructions to be connected with a tutor. Please do not click on any links on this page until after we have disconnected” (217. In several cases librarians were preoccupied with defining their roles—for example, specifying that they could give reference help but not advice. In all, the distancing mechanisms used by librarians, combined with occasional inaccurate referrals and technical problems with the software, were seen to create an enormous potential forfrustration on the part of the student. Conclusions – The most important implication of the study was that librarians and students were worlds (or planets apart in their approach to the reference interaction. While “teens attempted to create meaningby recreating the chat discourse environment in which they were most at home”, librarians “tried to create meaning in a parallel discourse environment that duplicated as much as possible the standard impersonal protocols of a face‐to‐face reference counter” (223. One suggested way to alleviate the disconnect between librarians and students was to involve students in the planning of the services. For now, however, the authors conclude that “teens are from Neptune, librarians are from Pluto. Better services would result if they could meet somewhere closer together” (224.

  13. Alpha-decay studies of the new isotopes sup 1 sup 9 sup 1 At and sup 1 sup 9 sup 3 At

    CERN Document Server

    Kettunen, H; Grahn, T; Greenlees, P T; Jones, P; Julin, R; Juutinen, S; Keenan, A; Kuusiniemi, P; Leino, M; Leppaenen, A P; Nieminen, P; Pakarinen, J; Rahkila, P; Uusitalo, J

    2003-01-01

    Detailed alpha-decay studies have been performed for the neutron-deficient isotopes sup 1 sup 9 sup 1 At and sup 1 sup 9 sup 3 At. The nuclei were produced in fusion-evaporation reactions of sup 5 sup 4 Fe and sup 5 sup 6 Fe ions with a sup 1 sup 4 sup 1 Pr target. The fusion products were separated in-flight using a gas-filled recoil separator and implanted into a position-sensitive silicon detector. The isotopes were identified using position, time and energy correlations between the implants and subsequent alpha-decays. Three alpha-decaying states were identified for sup 1 sup 9 sup 3 At and two for sup 1 sup 9 sup 1 At. The spin and parity of the initial states in the astatine isotopes were deduced based on unhindered alpha-decays to states in the bismuth daughter nuclei. In both astatine isotopes the 1/2 sup + intruder state was determined to be the ground state and a 7/2 sup - state to be the first-excited state. In sup 1 sup 9 sup 3 At the alpha-decay of the 13/2 sup + state was observed in coincidence...

  14. Rationalization of the solvation effects on the AtO+ ground-state change.

    Science.gov (United States)

    Ayed, Tahra; Réal, Florent; Montavon, Gilles; Galland, Nicolas

    2013-09-12

    (211)At radionuclide is of considerable interest as a radiotherapeutic agent for targeted alpha therapy in nuclear medicine, but major obstacles remain because the basic chemistry of astatine (At) is not well understood. The AtO(+) cationic form might be currently used for (211)At-labeling protocols in aqueous solution and has proved to readily react with inorganic/organic ligands. But AtO(+) reactivity must be hindered at first glance by spin restriction quantum rules: the ground state of the free cation has a dominant triplet character. Investigating AtO(+) clustered with an increasing number of water molecules and using various flavors of relativistic quantum methods, we found that AtO(+) adopts in solution a Kramers restricted closed-shell configuration resembling a scalar-relativistic singlet. The ground-state change was traced back to strong interactions, namely, attractive electrostatic interactions and charge transfer, with water molecules of the first solvation shell that lift up the degeneracy of the frontier π* molecular orbitals (MOs). This peculiarity brings an alternative explanation to the highly variable reproducibility reported for some astatine reactions: depending on the production protocols (with distillation in gas-phase or "wet chemistry" extraction), (211)At may or may not readily react. PMID:23944251

  15. Protein (Cyanobacteria): 294385 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available YP_007105521.1 1117:5160 1118:2838 1129:209 1173263:841 parallel beta-helix repeat (two copie...NLIEGNRQTGITILGNSSPDLGNADSLGNNRIRNNLLRDVQYTGTEAIAAVGNEISRLSGNIQLSGTLQSQPLSVPNISSAPNVSPNLPNGVTRTIIPNSVIVRTLPIE

  16. 77 FR 69638 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2012-11-20

    ... and Human Development Special Emphasis Panel; Contraceptive Clinical Trail Network: Female Sites. Date... Research; 93.209, Contraception and Infertility Loan Repayment Program, National Institutes of Health,...

  17. 77 FR 69641 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2012-11-20

    ... Development Special Emphasis Panel; Contraceptive Clinical Trail Network: Female Sites. Date: December 7, 2012....209, Contraception and Infertility Loan Repayment Program, National Institutes of Health, HHS)...

  18. 78 FR 11660 - Eunice Kennedy Shriver National Institute of Child Health & Human Development; Notice of Closed...

    Science.gov (United States)

    2013-02-19

    ... Development Special Emphasis Panel; Heart Placental Axis Development and Prevention of Cardiovascular Birth... Children; 93.929, Center for Medical Rehabilitation Research; 93.209, Contraception and Infertility...

  19. 2 CFR 1125.1010 - Suspending official (DoD supplement to Governmentwide definition at 2 CFR 180.1010).

    Science.gov (United States)

    2010-01-01

    ... Governmentwide definition at 2 CFR 180.1010). 1125.1010 Section 1125.1010 Grants and Agreements Federal Agency... Definitions § 1125.1010 Suspending official (DoD supplement to Governmentwide definition at 2 CFR 180.1010... identified in 48 CFR part 209, subpart 209.4, as suspending officials for procurement contracts....

  20. Indian national information programme for marine science

    Digital Repository Service at National Institute of Oceanography (India)

    Tapaswi, M.P.

    stream_size 11 stream_content_type text/plain stream_name Natl_Inf_Policies_Program_1991_209.pdf.txt stream_source_info Natl_Inf_Policies_Program_1991_209.pdf.txt Content-Encoding ISO-8859-1 Content-Type text/plain; charset...

  1. AcEST: BP921018 [AcEST

    Lifescience Database Archive (English)

    Full Text Available HAD-hydrolase MK0970 OS=Met... 44 2e-04 sp|Q3UGR5|HDHD2_MOUSE Haloacid dehalogena...311|Y209_METTH Uncharacterized HAD-hydrolase MTH_209 OS=Me... 45 1e-04 sp|Q8TWR2|Y970_METKA Uncharacterized

  2. 32 CFR 516.15 - General.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true General. 516.15 Section 516.15 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY AID OF CIVIL AUTHORITIES AND PUBLIC RELATIONS... Regulation Supplement, section 209.406-3 (48 CFR 209.406-3); reporting the exercise of criminal...

  3. 32 CFR 516.67 - Overseas cases of fraud or corruption.

    Science.gov (United States)

    2010-07-01

    ... suspension and debarment actions are governed by DFARS 209.403 (48 CFR 209.403). The names of all firms and... 32 National Defense 3 2010-07-01 2010-07-01 true Overseas cases of fraud or corruption. 516.67... AUTHORITIES AND PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.67...

  4. 78 FR 721 - California State Nonroad Engine Pollution Control Standards; Transport Refrigeration Units...

    Science.gov (United States)

    2013-01-04

    ... 209(e) of the Clean Air Act, or are not subject to Clean Air Act preemption. \\4\\ 74 FR 3030 (January... 209(b) motor vehicle waivers).\\7\\ \\5\\ 59 FR 36969 (July 20, 1994). \\6\\ 62 FR 67733 (December 30, 1997... or fire) associated with compliance with the California standard. \\7\\ 59 FR 36969 (July 20, 1994)....

  5. 40 CFR 60.106 - Test methods and procedures.

    Science.gov (United States)

    2010-07-01

    ... shall be used to determine opacity. (c) If auxiliary liquid or solid fossil-fuels are burned in an... = Heat input rate from solid or liquid fossil fuel, million J/hr (million Btu/hr). Rc = Coke burn-off... basis, ppm or g/dscm 20.9c = 20.9 percent oxygen−0.0 percent oxygen (defined oxygen correction...

  6. 40 CFR 225.3 - Procedure for invoking economic impact.

    Science.gov (United States)

    2010-07-01

    ... accordance with 33 CFR 209.120 and 209.145. (b) If the decision of the Chief of Engineers is that ocean... 40 Protection of Environment 24 2010-07-01 2010-07-01 false Procedure for invoking economic impact... DUMPING CORPS OF ENGINEERS DREDGED MATERIAL PERMITS § 225.3 Procedure for invoking economic impact....

  7. Drug: D03690 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D03690 Drug Desciclovir (USAN/INN) C8H11N5O2 209.0913 209.2052 D03690.gif Antiviral...08307] Antivirals Anti-HSV agent DNA polymerase inhibitor Purine analogue Desciclovir D03690 Desciclovir (US

  8. EST Table: DC532825 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available DC532825 E_ET_J150_02A06_R_0 10/09/28 64 %/209 aa ref|XP_002093380.1| GE20793 [Dros...ophila yakuba] gb|EDW93092.1| GE20793 [Drosophila yakuba] 10/09/01 64 %/209 aa FBpp0265803|DyakGE20793-PA 10

  9. 49 CFR 1544.229 - Fingerprint-based criminal history records checks (CHRC): Unescorted access authority, authority...

    Science.gov (United States)

    2010-10-01

    ... certification made to an airport operator on or after December 6, 2001, pursuant to 14 CFR 107.209(n) in effect prior to November 14, 2001 (see 14 CFR parts 60 to 139 revised as of January 1, 2001) or § 1542.209(n... employee or contract employee covered under a certification made to an airport operator pursuant to 14...

  10. 32 CFR 516.61 - Reporting requirements.

    Science.gov (United States)

    2010-07-01

    ... PUBLIC RELATIONS LITIGATION Remedies in Procurement Fraud and Corruption § 516.61 Reporting requirements... is requested by PFD, the provisions of DFARS 209.406-3 (48 CFR 209.406-3) will be followed. That... this information to assist them in taking appropriate administrative, contractual, and civil...

  11. 33 CFR 263.12 - References.

    Science.gov (United States)

    2010-07-01

    ... and Appearance of Feasibility Reports. (f) ER 1105-2-502 Public Meetings (33 CFR 209.405). (g) ER 1105-2-507 Preparation and Coordination of Environmental Statements (33 CFR 209.410). (h) ER 1105-2-800 Public Involvement: General Policies (33 CFR 380). (i) ER 1105-2-811 A-95 Clearinghouse Coordination...

  12. Drug: D08558 [KEGG MEDICUS

    Lifescience Database Archive (English)

    Full Text Available D08558 Drug Talipexole (INN) C10H15N3S 209.0987 209.3112 D08558.gif Antiparkinsonia...ceptor interaction hsa04728(1813) Dopaminergic synapse map07057 Antiparkinsonian agents map07213 Dopamine re

  13. Pyrolysis and its influence factors of decabromodiphenyl ether%十溴联苯醚的热解及其影响因素研究

    Institute of Scientific and Technical Information of China (English)

    刘芃岩; 张雅婧; 张彦娜; 张瑞瑞; 孙佳慧

    2016-01-01

    This study investigates influence factors and thermal degradation of decabromodiphenyl ether (BDE-209) under the temperature range of 200~300℃.The results indicated that pyrolysis of BDE-209 was affected by temperature, time and common metal salts which were produced during the manufacturing and processing of printed circuit boards, such as copper nitrate, ferric chloride, aluminum chloride and zinc chloride. Pyrolysis of BDE-209 could be accelerated with the rise of temperature and extension of pyrolysis time. Results showed a greater impact of temperature on pyrolysis than that of time. A significant acceleration of pyrolysis was detected with copper nitrate, ferric chloride and aluminum chloride with degradation rates of BDE-209 in copper nitrate > ferric chloride > aluminum chloride. Pyrolysis of BDE-209 was inhibited with the presence of zinc chloride. Acceleration of aluminum chloride and inhibition of zinc chloride were weakened with the increase of temperature. This research results can provide a scientific basis for further study on the release and degradation of BDE-209 from electronic waste during the thermal treatment.%在200~300℃的温度范围内研究了十溴联苯醚(BDE-209)的热降解及其影响因素.结果表明,温度、时间以及硝酸铜、三氯化铁、氯化铝和氯化锌等处理线路板过程中产生的金属盐对BDE-209热降解有不同的影响.升高温度或延长热解时间均能促进BDE-209的热解,且温度对BDE-209降解的影响程度大于时间对其降解的影响;硝酸铜、三氯化铁和氯化铝对BDE-209的热解均起促进作用,促进作用的顺序为:硝酸铜>三氯化铁>氯化铝;氯化锌对BDE-209的热解有抑制作用;随着温度的升高,氯化铝和氯化锌对BDE-209热降解的影响减弱.该研究结果可为深入探究电子垃圾热处理过程中BDE-209的释放及降解提供科学依据.

  14. Fate and ecological effects of decabromodiphenyl ether in a field lysimeter.

    Science.gov (United States)

    Du, Wenchao; Ji, Rong; Sun, Yuanyuan; Zhu, Jianguo; Wu, Jichun; Guo, Hongyan

    2013-08-20

    Flame-retardant polybrominated diphenyl ethers (PBDEs) are environmental contaminants. Deca-BDE is increasingly used commercially, but little is known about the long-term fate and impact of its major component, decabromodiphenyl ether (BDE-209), on the soil environment. In this study, we investigated the fate and ecological effect of BDE-209 over 4 years in outdoor lysimeters in a field planted with a rice-wheat rotation. BDE-209 and six lower-brominated PBDEs (BDE-28, -47, -99, -153, -154, and -183) were detected in soil layers of the test lysimeter. We calculated an average BDE-209 migration rate of 1.54 mg·m(-2)·yr(-1). In samples collected in May 2008, November 2008, November 2009, November 2010, and November 2011, 95.5%, 94.3%, 108.1%, 33.8%, and 35.5% of the spiked BDE-209 were recovered, respectively. We predicted the major pathway for debromination of BDE-209 in soil to be: BDE-209→BDE-183→BDE-153/BDE-154→BDE-99→BDE-47→BDE-28. In plants, BDE-209 and seven lower-brominated PBDEs (BDE-28, -47, -99, -100, -153, -154, and -183) were detected. BDE-100 was mainly derived from the debromination of BDE-154 in plants, but sources of other lower-brominated PBDEs were still difficult to determine. In soils containing BDE-209 for 4 years, soil urease activity increased, and soil protease activity slightly decreased. Our results provide important insights for understanding the behavior of BDE-209 in agricultural soils. PMID:23899302

  15. New developments of the in-source spectroscopy method at RILIS/ISOLDE

    CERN Document Server

    Marsh, B A; Imai, N; Seliverstov, M D; Rothe, S; Sels, S; Capponi, L; Rossel, R E; Franchoo, S; Wendt, K; Focker, G J; Kalaninova, Z; Sjoedin, A M; Popescu, L; Nicol, T; Huyse, M; Radulov, D; Atanasov, D; Kesteloot, N; Borgmann, Ch; Cocolios, T E; Lecesne, N; Ghys, L; Pauwels, D; Rapisarda, E; Kreim, S; Liberati, V; Wolf, R N; Andel, B; Schweikhard, L; Lane, J; Derkx, X; Kudryavtsev, Yu; Zemlyanoy, S G; Fedosseev, V N; Lynch, K M; Rosenbusch, M; Van Duppen, P; Lunney, D; Manea, V; Barzakh, A E; Andreyev, A N; Truesdale, V; Flanagan, K T; Molkanov, P L; Koester, U; Van Beveren, C; Wienholtz, F; Goodacre, T Day; Antalic, S; Bastin, B; De Witte, H; Fink, D A; Fedorov, D V

    2013-01-01

    At the CERN ISOLDE facility, long isotope chains of many elements are produced by proton-induced reactions in target materials such as uranium carbide. The Resonance Ionization Laser Ion Source (RILIS) is an efficient and selective means of ionizing the reaction products to produce an ion beam of a chosen isotope. Coupling the RILIS with modern ion detection techniques enables highly sensitive studies of nuclear properties (spins, electromagnetic moments and charge radii) along an isotope chain, provided that the isotope shifts and hyperfine structure splitting of the atomic transitions can be resolved. At ISOLDE the campaign to measure the systematics of isotopes in the lead region (Pb, Bi, Tl and Po) has been extended to include the gold and astatine isotope chains. Several developments were specifically required for the feasibility of the most recent measurements: new ionization schemes (Po, At); a remote controlled narrow line-width mode of operation for the RILIS Ti:sapphire laser (At, Au, Po); isobar fr...

  16. Development of 211At Chemistry for Labelling Biomolecules

    International Nuclear Information System (INIS)

    Our studies have demonstrated that high recovery of 211At can be obtained using a “wet chemistry” approach to isolation from the bismuth target. We have also demonstrated that direct labelling of antibody-B10 conjugates with 211At can be performed in high yields, and that the astatinated antibodies are stable to in vivo deastatination. While these results will allow us to enter clinical studies with 211At-labelled antibodies, the chemistry associated with 211At is not fully understood. Therefore, it is important that many more basic studies to be conducted with 211At, so the optimal labelling reagent for each type of disease-targeting agent becomes apparent

  17. Alpha particle induced DNA damage and repair in normal cultured thyrocytes of different proliferation status

    DEFF Research Database (Denmark)

    Lyckesvärd, Madeleine Nordén; Delle, Ulla; Kahu, Helena;

    2014-01-01

    Childhood exposure to ionizing radiation increases the risk of developing thyroid cancer later in life and this is suggested to be due to higher proliferation of the young thyroid. The interest of using high-LET alpha particles from Astatine-211 ((211)At), concentrated in the thyroid by the same...... levels of γH2AX decreased during the first 24h in both cycling and stationary cultures and complete repair was seen in all cultures but cycling cells exposed to (211)At. Compared to stationary cells alpha particles were more harmful for cycling cultures, an effect also seen at the pChk2 levels...... cultures at a modest level of damage, clearly demonstrating that cell cycle status influences the relative effectiveness of alpha particles....

  18. EFFECT OF MECHANICAL PROPERTIES OF MARTENSITE AND LOADING RATE ON DUAL PHASE STEELS

    Directory of Open Access Journals (Sweden)

    Ali BAYRAM

    1998-03-01

    Full Text Available In this study, steel sheet materials were used in order to obtain dual-phase steel. Specimens for this purpose have been annealed in ferrite + astatine regions at the temperatures of 740, 760, 800 and 820 °C. The specimens were annealed at the different temperatures with corresponding times 20, 40 and 60 minutes and quenched into water. As a result of this dual-phase steels at different ferrite + martensite ratio were produced. Sheet specimens were tested at the range of loading rates of 10, 50 and 259 mm/min. Strength properties of dual-phase steels were investigated depending on annealing temperature, ratio of martensite and loading rate.

  19. New developments of the in-source spectroscopy method at RILIS/ISOLDE

    Energy Technology Data Exchange (ETDEWEB)

    Marsh, B.A., E-mail: bruce.marsh@cern.ch [CERN, CH-1211 Geneva (Switzerland); Andel, B. [Comenius University, Bratislava (Slovakia); Andreyev, A.N. [University of York, Department of Physics, York YO10 5DD (United Kingdom); Antalic, S. [Comenius University, Bratislava (Slovakia); Atanasov, D. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Barzakh, A.E. [Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, 188300 Gatchina (Russian Federation); Bastin, B. [Grand Accérateur National d’Ions Lourds (GANIL), Bd Henri Becquerel, F-14076 Caen (France); Borgmann, Ch. [Max-Planck-Institut für Kernphysik, Saupfercheckweg 1, 69117 Heidelberg (Germany); Capponi, L. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Cocolios, T.E.; Day Goodacre, T. [CERN, CH-1211 Geneva (Switzerland); University of Manchester, Manchester (United Kingdom); Dehairs, M. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Derkx, X. [University of the West of Scotland, School of Engineering, Paisley PA1 2BE (United Kingdom); De Witte, H. [KU Leuven, Celestijnenlaan 200D, B-3001 Leuven (Belgium); Fedorov, D.V. [Petersburg Nuclear Physics Institute, NRC Kurchatov Institute, 188300 Gatchina (Russian Federation); Fedosseev, V.N.; Focker, G.J. [CERN, CH-1211 Geneva (Switzerland); Fink, D.A. [Ruprecht-Karls Universität, Seminarstr. 2, 69117 Heidelberg (Germany); CERN, CH-1211 Geneva (Switzerland); Flanagan, K.T. [University of Manchester, Manchester (United Kingdom); Franchoo, S. [CSNSM-IN2P3-CNRS, Université Paris-Sud, 91406 Orsay (France); and others

    2013-12-15

    Highlights: • Upgrade of the lasers, detectors and data acquisition for in-source resonance ionization spectroscopy at ISOLDE. • First use of the ISOLTRAP MR-ToF MS in combination with laser spectroscopy at ISOLDE. • Resonance ionization of astatine for the study of its nuclear structure. -- Abstract: At the CERN ISOLDE facility, long isotope chains of many elements are produced by proton-induced reactions in target materials such as uranium carbide. The Resonance Ionization Laser Ion Source (RILIS) is an efficient and selective means of ionizing the reaction products to produce an ion beam of a chosen isotope. Coupling the RILIS with modern ion detection techniques enables highly sensitive studies of nuclear properties (spins, electromagnetic moments and charge radii) along an isotope chain, provided that the isotope shifts and hyperfine structure splitting of the atomic transitions can be resolved. At ISOLDE the campaign to measure the systematics of isotopes in the lead region (Pb, Bi, Tl and Po) has been extended to include the gold and astatine isotope chains. Several developments were specifically required for the feasibility of the most recent measurements: new ionization schemes (Po, At); a remote controlled narrow line-width mode of operation for the RILIS Ti:sapphire laser (At, Au, Po); isobar free ionization using the Laser Ion Source Trap, LIST (Po); isobar selective particle identification using the multi-reflection time-of-flight mass separator (MR-ToF MS) of ISOLTRAP (Au, At). These are summarized as part of an overview of the current status of the in-source resonance ionization spectroscopy setup at ISOLDE.

  20. Remediation of polybrominated diphenyl ethers in soil using Ni/Fe bimetallic nanoparticles: Influencing factors, kinetics and mechanism

    Energy Technology Data Exchange (ETDEWEB)

    Xie, Yingying [School of Chemistry and Environment, South China Normal University, Guangzhou 51006 (China); Guangdong Technology Research Center for Ecological Management and Remediation of Urban Water System, Guangzhou 51006 (China); Fang, Zhanqiang, E-mail: zhqfang@scnu.edu.cn [School of Chemistry and Environment, South China Normal University, Guangzhou 51006 (China); Guangdong Technology Research Center for Ecological Management and Remediation of Urban Water System, Guangzhou 51006 (China); Cheng, Wen [School of Chemistry and Environment, South China Normal University, Guangzhou 51006 (China); Guangdong Technology Research Center for Ecological Management and Remediation of Urban Water System, Guangzhou 51006 (China); Tsang, Pokeung Eric [Department of Science and Environmental Studies, The Hong Kong Institute of Education, Hong Kong 00852 (China); Zhao, Dongye [Environmental Engineering Program, Department of Civil Engineering, Auburn University, Auburn, AL 36849 (United States)

    2014-07-01

    Polybrominated diphenyl ethers (PBDEs) are commonly used as additive flame retardants in all kinds of electronic products. PBDEs are now ubiquitous in the environment, with soil as a major sink, especially in e-waste recycling sites. This study investigated the degradation of decabromodiphenyl ether (BDE209) in a spiked soil using Ni/Fe bimetallic nanoparticles. The results indicated that Ni/Fe bimetallic nanoparticles are able to degrade BDE209 in soil at ambient temperature and the removal efficiency can reach 72% when an initial pH of 5.6 and at a Ni/Fe dosage of 0.03 g/g. A declining trend in degradation was noticed with decreasing Ni loading and increasing of initial BDE209 concentration. The degradation products of BDE209 were analyzed by GC-MS, which showed that the degradation of BDE209 was a process of stepwise debromination from nBr to (n − 1)Br. And a possible debromination pathway was proposed. At last, the degradation process was analyzed as two-step mechanism, mass transfer and reaction. This current study shows the potential ability of Ni/Fe nanoparticles to be used for removal of PBDEs in contaminated soil. - Highlights: • Ni/Fe bimetallic nanoparticles could effectively degradate BDE209 in soil. • The effects of various factors on remediation of BDE209 in soil using Ni/Fe were considered. • The degradation of BDE209 was a process of stepwise debromination from nBr to (n − 1)Br. • A possible debromination pathway and mechanism about removal of BDE209 in soil were proposed.

  1. Polybrominated diphenyl ethers (PBDES) at a solid waste incineration plant I: Atmospheric concentrations

    Science.gov (United States)

    Agrell, Cecilia; ter Schure, Arnout F. H.; Sveder, Jeanette; Bokenstrand, Alma; Larsson, Per; Zegers, Bart N.

    2004-09-01

    In the first of two papers, the atmospheric poly brominated diphenyl ether (PBDE) concentrations at a municipal solid waste incineration (MSW) plant with electronic recycling is compared with that at an industrial urban reference site producing asphalt and concrete. In the second paper, atmospheric deposition and washout behaviour is presented (Atmos. Environ. (2004a)). PBDEs (BDE28, -47, -66, -100, -154, -153, -183, -209) in the gaseous and particulate phase were measured with high resolution in time during the colder parts of the year to minimise the influence of potential historical pollution at the sites through volatilisation. This also means that reported levels are lower compared to other reported data. Results of BDE47 (TetraBDE) and BDE209 (DecaBDE) as representatives of "old" vs. "new" PBDEs as well as ∑PBDE, excluding BDE209, are presented. Median ∑PBDE, BDE47 and BDE209 concentration were 6.3, 2.1 and 10.4 pg m-3 at the MSW and 3.5, 1.7 and 6.5 pg m-3 at the reference site. The total concentrations (gaseous and particulate phase) were significantly higher at the MSW compared to the reference site for ∑PBDE and BDE47 but not for BDE209. The same results were obtained regarding concentrations in the gaseous phase. Particle concentrations were significantly higher at the MSW for ∑PBDE, BDE47 and BDE209. Within each site, the gaseous-phase concentration was significantly higher than the particulate-phase concentration except for BDE209 at the MSW. Thus, the proportion of BDE209 detected in the particulate phase was higher at the MSW compared to the reference site. Together with the results of the second paper, we suggest that treatment of waste is presently a source of "old" PBDEs to the environment, whereas the rather similar BDE209 concentrations at the two sites are more a result of proximity to potential diffuse sources.

  2. Probing a potential in vivo drug-excipient interaction: temporal effects of a modified β-cyclodextrin on the intravenous pharmacokinetics of a model high-affinity drug ligand.

    Science.gov (United States)

    Mannila, Anne; Morizzi, Julia; Nguyen, Thuy Tien; Charman, Susan A; McIntosh, Michelle P; Shackleford, David M

    2012-09-01

    The investigational synthetic ozonide, OZ209, has previously been shown to have high binding affinity for sulfobutylether(7)-β-cyclodextrin [(SBE)(7)-β-CD] resulting in altered pharmacokinetics when administered intravenously to rats in a (SBE)(7)-β-CD aqueous formulation. In the present study, OZ209 and (SBE)(7)-β-CD have been used to probe whether a modified β-CD excipient, on systemic administration, can bind to and alter the pharmacokinetics of a coadministered drug. When (SBE)(7)-β-CD was administered 60 min after OZ209, a spike in the concentration of OZ209 in blood and plasma was detected within 2 min of the (SBE)(7)-β-CD infusion, and this was accompanied by a temporary decrease in the whole blood-to-plasma partitioning ratio of OZ209, the duration of which was dependent upon the dose of (SBE)(7)-β-CD. Administration of (SBE)(7)-β-CD also resulted in increased urinary excretion of OZ209. By contrast, administration of (SBE)(7)-β-CD 4 h prior to OZ209 had no pronounced effect on the blood or plasma pharmacokinetics of OZ209, consistent with the (SBE)(7)-β-CD having been largely eliminated prior to the administration of OZ209. This study is the first to demonstrate an in vivo drug-excipient interaction between a modified β-CD and a coadministered drug, and also demonstrates that such an interaction can be avoided through appropriate consideration of CD pharmacokinetics. PMID:22549698

  3. Kolmnurkkelmus, vahendlikult toimepandud vargus ja nõude omastamine. Riigikohtu kriminaalkolleegiumi otsus 3-1-1-85-11 / Kristina Domaškina

    Index Scriptorium Estoniae

    Domaškina, Kristina

    2012-01-01

    Riigikohtu lahendist 3-1-1-85-11, mis käsitleb varguse, kelmuse ja omastamise objektiivsete koosseisude temaatikat. Materiaalõiguslikest küsimustest karistusseadustiku paragrahvide 199, 209 ja 201 järgi

  4. Constructing and Analyzing Fusion Promoter of Partial Sericin 1 and Bombyx A3 Cytoplasmic Actin

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Previous report showed that the 209 bp DNA sequence upstream of the sericin 1 transcriptional start site (-586 to -378 bp) is involved in promoting transcription and responsible for the tissue specificity of sericin 1 promoter in silkworm Bombyx mori. In the present study, this 209 bp sequence exhibited enhancive effect by assembling in two different locations of ubiquitous Bombyx A3 cytoplasmic actin promoter. Sf-9 cells were transfected with recombinant plasmids using Cellfectin reagent. Firefly luciferase gene located downstream of fusion promoter was considered as a reporter, whereas the activity of the co-transfected Renilla luciferase gene (pGL2-SV40) provides an internal control. This 209 bp region up-regulates the strength of A3 promoter significantly (P < 0.01) when it enters into A3 promoter with respect to the position in sericin 1 gene promoter. This 209-bp fragment was almost functionless when being located upstream of A3 promoter.

  5. Colloidal Silver Products

    Science.gov (United States)

    ... Events Multimedia (Video, Images, and Audio) NCCIH Clinical Digest A monthly newsletter with evidence-based information on ... require a viewer such as the free Adobe Reader . NCCIH Pub No.: D209 Date Created: May 2004 ...

  6. Dicty_cDB: Contig-U16339-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available ifiysin*kv*vckaytnynkpdcgplg kgsiedgkiytfssfmcwtgcdrlakiakslkiplrahfwqesankikeemmercfnkek nsfvstwdgddvdpylll..., Expect(2) = 0.0 Identities = 209/210 (99%), Positives = 210/210 (100%) Frame = +3 Query: 1578 KAYTNYNKPDCGPLGKGSIEDGKIYTFSSFMCW...TGCDRLAKIAKSLKIPLRAHFWQESAN 1757 +AYTNYNKPDCGPLGKGSIEDGKIYTFSSFMCWTGCDRLAKIAKSLKIPLRAHF...WQESAN Sbjct: 418 QAYTNYNKPDCGPLGKGSIEDGKIYTFSSFMCWTGCDRLAKIAKSLKIPLRAHFWQESAN 47

  7. Dicty_cDB: Contig-U02156-1 [Dicty_cDB

    Lifescience Database Archive (English)

    Full Text Available tagat 125 Query: 126 ttaccnaatgggacccntttnaatttatc 154 ||||||||||||||||||||||||||||| Sbjct: 126 ttaccnaatggg...||||||| Sbjct: 268 aganatcnaattaanatttggcnattagggtcnactaatgataanaatganaatttagat 209 Query: 126 ttaccnaatggga...cccntttnaatttatc 154 ||||||||||||||||||||||||||||| Sbjct: 208 ttaccnaatgggacccntttnaatttatc 180 Score = 143 ...|||||||||||||||||||||||||||||||||||||||||| Sbjct: 66 aganatcnaattaanatttggcnattagggtcnactaatgataanaatganaatt

  8. Cognitive load theory

    OpenAIRE

    Kirschner, Paul A.; Kirschner, Femke; Paas, Fred

    2010-01-01

    Kirschner, P. A., Kirschner, F. C., & Paas, F. (2009). Cognitive load theory. In E. M. Anderman & L. H. Anderman (Eds.). Psychology of classroom learning: An encyclopedia, Volume 1, a-j (pp. 205-209). Detroit, MI: Macmillan Reference.

  9. Determination of cross-section starting from a decay curve composed of two halves lives; Determinacion de la seccion eficaz a partir de una curva de decaimiento compuesta de dos vidas medias

    Energy Technology Data Exchange (ETDEWEB)

    Martinez Q, E.; Aguilera, E.F. [Instituto Nacional de Investigaciones Nucleares, Departamento del Acelerador, A.P. 18-1027, 11801 Mexico D.F. (Mexico)

    1998-07-01

    It is presented a method developed to determine the cross section of 3n channel of the fusion reaction {sup 6} He + {sup 209} Bi which is based in the {alpha} decay curve of residual nucleus, {sup 212} At. (Author)

  10. 78 FR 70308 - Prospective Grant of Exclusive License: Development of Chitosan/IL-12 Conjugate as...

    Science.gov (United States)

    2013-11-25

    ... Health, HHS. ACTION: Notice. SUMMARY: This is notice, in accordance with 35 U.S.C. 209 and 37 CFR Part... or a chitosan derivative. Similar compositions are described wherein chitosan or a derivative forms...

  11. 77 FR 4895 - New Animal Drugs; Chloramphenicol, Diethylcarbamazine Citrate, Hygromycin B, Methoxyflurane...

    Science.gov (United States)

    2012-02-01

    ... Drugs; Chloramphenicol, Diethylcarbamazine Citrate, Hygromycin B, Methoxyflurane, Neomycin Sulfate... Affiliate of IGI, ane, prednisolone, Inc., Box 209, tetracaine, Harding Hwy., neomycin sulfate). Buena, NJ 08310. NADA 044-655 NEOMYCANE Ophthalmic Evsco Ointment (neomycin Pharmaceuticals, an...

  12. Melbourne Eesti Ühing Kodu aasta peakoosolek / Sirje Jõgi

    Index Scriptorium Estoniae

    Jõgi, Sirje

    2007-01-01

    18. märtsil, ühingus on 209 liiget ja viis auliiget. Esitati aruanded, valiti uus 9 liikmeline juhatus: Bruno Metsar, Glory Toom, Milvi Vaikma, Sirje Jõgi, Rolf Luik, Imbi Knappstein, Rein Valling, Diana Ritchie ja Siiri Taveter

  13. 75 FR 6740 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Science.gov (United States)

    2010-02-10

    ... Act Release No. 60711 (September 23, 2009), 74 FR 49419 (September 28, 2009) (order approving SR... Abercrombie & Fitch Co. 187 MMM 3M Co. 172 APC Anadarko Petroleum Corp. 140 MU Micron Technology Inc. 209...

  14. 铜绿假单胞菌胞内酶粗提液对十溴联苯醚的降解%Biodegradation of Decabromodiphenyl Ether by Intracellular Enzyme Obtained from Pseudomonas aeruginosa

    Institute of Scientific and Technical Information of China (English)

    史广宇; 尹华; 叶锦韶; 彭辉; 张娜; 何宝燕

    2013-01-01

    探讨了铜绿假单胞菌粗酶液对十溴联苯醚(BDE-209)的降解特性,结果表明,该菌株胞内酶在12h内对1 mg·L-1的BDE-209降解率达到了69.22%,温度、pH值、酶蛋白浓度及底物BDE-209浓度均会影响胞内酶粗提液对BDE-209的降解效率.当BDE-209浓度为1 mg·L-时,BDE-209适宜的酶促降解条件为:温度30℃,反应pH值7.5,且降解率随着酶浓度的增加而增大.胞内酶对BDE-209的降解过程符合一级动力学反应模型,底物浓度为1mg· L-时降解速率最快,半衰期为6.9h.胞内酶降解BDE-209符合高浓度底物抑制的酶促反应类型,其基本降解动力学参数为rma =0.133 mg·(L·h)-1,Km=0.642mg·L-1,Ki=1.558 mg·L-1.%The degradation characteristics of decabromodiphenyl ether (BDE-209) by crude enzyme from Pseudomonas aeruginosa were investigated. The results revealed that the degradation efficiency of the intracellular enzyme excreted from this bacterial strain reached 69.22% after incubation with 1 mg·L-1 BDE-209 for 12 h. Temperature, pH, enzyme concentration and BDE-209 concentration all influenced the ability of crude enzyme to degrade BDE-209. When the BDE-209 concentration was 1 mg·L , the optimal condition for enzymatic degradation was temperature 30℃ and pH 7. 5 , and the degradation rate increased with increasing enzyme concentration. The degradation process of BDE- 209 by intracellular enzyme of the strain conformed to the first-order kinetic model. The highest reaction rate was achieved when the initial concentration of BDE-209 was 1 mg·L and the half-life of this substrate was 6. 9 h. In addition, the biodegradation of BDE-209 can be well described by enzymatic reaction of high concentration substrate inhibition, with a maximum substrate utilization rate of 0. 133 mg·(L·h)-1 , a Michaelis-Menten constant of 0. 642 mg·L-1 , and an inhibitory constant of 1. 558 mg·L , respectively.

  15. Cool dwarfs in wide multiple systems. Paper 3: Two common-proper-motion, late-type stars separated by over 11 arcmin

    CERN Document Server

    Caballero, J A; Miret, F X; Tobal, T; Cairol, J

    2012-01-01

    LP 209-28 and LP 209-27 have similar proper motions as tabulated by several catalogues. Using seven astrometric epochs spanning 59 years, we confirm a common tangential velocity by measuring a constant angular separation of rho = 666.62+/-0.09 arcsec. Accurate SDSS and 2MASS photometry indicates that they are normal dwarfs of approximate spectral types K7 V and M3 V. However, from their apparent magnitudes, both LP 209-28 and LP 209-27 are located at 200-250 pc, from where one can deduce an astonishing projected physical separation of 0.6-0.8 pc. The system Koenigstuhl 6 AB represents another world record among the least-bound systems with low-mass star components.

  16. Organisation and methods for the transport of dangerous goods by road

    International Nuclear Information System (INIS)

    This article reviews certain parts of Act No. 209 BGBL1 (1967) concerning the transport of dangerous goods by road. In particular, it sets out the dangerous goods, by class, covered by the Act and describes the labelling requirements. (NEA)

  17. Dexamethasone treatment differentially alters viral shedding and the antibody and acute phase protein response after multivalent respiratory vaccination in beef steers

    Science.gov (United States)

    Our objective was to examine immunosuppression induced by dexamethasone (DEX) administration in cattle upon immunological responses to a multivalent respiratory vaccine containing replicating and non-replicating agents. Steers ( n = 32; 209 +/- 8 kg) seronegative to infectious bovine rhinotracheitis...

  18. International Scientific Technology Exchanges in 2012

    Institute of Scientific and Technical Information of China (English)

    LI; Lin

    2012-01-01

    <正>In 2012, CIAE sent 209 teams abroad for taking part in international meeting, technical visiting, further studying and training. CIAE received 412 foreign scholars from about 30 countries, and some reports were given by foreign scholars as follows:

  19. 75 FR 6756 - Self-Regulatory Organizations; NYSE Arca, Inc.; Notice of Filing and Immediate Effectiveness of...

    Science.gov (United States)

    2010-02-10

    ... Act Release No. 60711 (September 23, 2009), 74 FR 49419 (September 28, 2009) (order approving SR... Corp. Inc. 209 ATVI Activision 177 NUE Nucor Corp. Blizzard Inc. 145 BBD Banco Bradesco SA. 157...

  20. 29 CFR 780.112 - General meaning of “agriculture or horticultural commodities.”

    Science.gov (United States)

    2010-07-01

    ... mineral wealth or other natural resources, or by uncultivated natural growth. For example, peat humus or peat moss is not an agricultural commodity. Wirtz v. Ti Ti Peat Humus Co., 373 f(2d) 209 (C.A.4)....

  1. Protein (Viridiplantae): 308813045 [PGDBj - Ortholog DB

    Lifescience Database Archive (English)

    Full Text Available otein involved in mRNA turnover (ISS) Ostreococcus tauri MPKSKRARVVSLTKTKKKDREWKSSIIDRARDALELRASAYVFKYTCMRNG...XP_003083829.1 33090:209 3041:6341 1035538:5129 13792:5129 70447:4042 70448:4808 Pr

  2. Distinguishing PCB Isomeric Congeners with their Gas Chromatographic and Mass Spectrometric Ortho Effect using Comprehensive Gas Chromatography

    Science.gov (United States)

    The 209 polychlorinated biphenyl (PCB) congeners and associated nine isomeric groups (nine groups of PCBs with the same degree of chlorination) have been long recorded as high endocrine disrupting chemicals in the environment. Difficult analytical problems exist, in those frequen...

  3. Main: 1MVN [RPSD[Archive

    Lifescience Database Archive (English)

    Full Text Available 1MVN シロイヌナズナ Arabidopsis Arabidopsis thaliana (L.) Heynh. Phosphopantothenoylcystei...Q9SWE5|EMBL; AF166262; AAD51616.1; -.|EMBL; AB026641; BAB01331.1; -.|PDB; 1E20; X-ray; A=1-209.|PDB; 1MVL; X-ray; A=1-209.|PDB; 1MV...VTLYTDEDEWSSWNKIGDPVLHIELRRWADVLVIAPLSANTLGKIAGGLCDNLLTCIIRAWDYTKPLFVAPAMNTLMWNNPFTERHLLSLDELGITLIPPIKKRLACGDYGNGAMAEPSLIYSTVRLFWESQAHQQTGGTS arabi_1MVN.jpg ...

  4. Interaction of Polybrominated Diphenyl Ethers and Aerobic Granular Sludge: Biosorption and Microbial Degradation

    OpenAIRE

    Shou-Qing Ni; Qingjie Cui; Zhen Zheng

    2014-01-01

    As a new category of persistent organic pollutants, polybrominated diphenyl ethers (PBDEs) have become ubiquitous global environmental contaminants. No literature is available on the aerobic biotransformation of decabromodiphenyl ether (BDE-209). Herein, we investigated the interaction of PBDEs with aerobic granular sludge. The results show that the removal of BDE-209 from wastewater is mainly via biosorption onto aerobic granular sludge. The uptake capacity increased when temperature, contac...

  5. Synthesis and docking analysis of new heterocyclic system of tetrazolo[5',1':2,3][1,3,4]thiadiazepino [7,6-b]quinolines as aldose reductase inhibitors

    Directory of Open Access Journals (Sweden)

    Mohammad Saadatmandzadeh

    2014-09-01

    Conclusion: All of the best models formed strong hydrogen bonds with Trp 111 and Tyr 209 via tetrazole moiety. It was found that pi-pi interaction between Tyr 209, Trp 20 and His 110 side chain and quinolin moiety was one of the common factors in enzyme-inhibitor junction. It was found that both hydrogen bonding and hydrophobic interactions are important in the structure and function of biological molecules, especially for inhibition in a complex.

  6. Experimental test of a new neutron threshold detector and its application

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The possibility of using 209Bi as a new threshold detector to measurc high-energy neutrons was investigated for the first time. At the same time the experiment measured successfully the emitted neutron fiuence rate, energy spectrum and dose equivalent rate distributions in the heavy ion target area using a detector complex including 209Bi, 115In, 27A1, 19F and 12C samples.

  7. 49 CFR 571.210 - Standard No. 210; Seat belt assembly anchorages.

    Science.gov (United States)

    2010-10-01

    ... protection requirements of S5.1 of Standard No. 208 (49 CFR 571.208). S4.1.3School bus passenger seats. S4.1... shall be Type 1 or Type 2 as defined in S3 of FMVSS No. 209 (49 CFR 571.209). S4.1.3.2Type 2 seat belt... structure. Small occupant seating position is as defined in 49 CFR 571.222. S4. Requirements. S4.1Type.......

  8. 20 CFR 725.219 - Duration of entitlement; child.

    Science.gov (United States)

    2010-04-01

    ...; (3) The child attains age 18; and (i) Is not a student (as defined in § 725.209(b)) during any part of the month in which the child attains age 18; and (ii) Is not under a disability (as defined in § 725.209(a)(2)(ii)) at that time; (4) If the child's entitlement beyond age 18 is based on his or...

  9. Role of projectile breakup in {sup 6}He and {sup 6}Li induced fusion reactions around barrier energies

    Energy Technology Data Exchange (ETDEWEB)

    Kumari, Anju; Kharab, Rajesh, E-mail: kharabrajesh@rediffmail.com

    2015-09-15

    The influence of projectile breakup on fusion cross section for {sup 6}He + {sup 209}Bi, {sup 6}He + {sup 64}Zn, {sup 6}Li + {sup 209}Bi and {sup 6}Li + {sup 64}Zn reactions at near barrier energies is studied within the framework of quantum diffusion approach. The breakup does not affect the fusion induced by {sup 6}He, whereas a significant suppression for {sup 6}Li induced reaction is observed in below barrier energy region.

  10. 49 CFR 571.222 - Standard No. 222; School bus passenger seating and crash protection.

    Science.gov (United States)

    2010-10-01

    ... minimum height of 520 mm above the seating reference point, as specified by S4.1.3.2(a) of 49 CFR 571.210... seat, shall also meet the requirements of: (i) S4.4.3.3 of Standard No. 208 (49 CFR 571.208); (ii) Standard No. 209 (49 CFR 571.209), as they apply to school buses; and, (iii) Standard No. 210 (49 CFR...

  11. Toxicokinetics and the related metabolites in rainbow trout(Oncorhynchus mykiss) after exposure to decabromodiphenyl ether

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    Decabromodiphenyl ether(BDE209) is poorly absorbed by mammals,and little information is available on the toxicokinetics of BDE209 and its metabolites in fish.In the present study,rainbow trout(Oncorhynchus mykiss) were administered to 100 ng/g and 500 ng/g body wet weight of BDE209 via a single intraperitoneal injection and parent BDE209 and its metabolites were sequentially monitored for 28 days.The results showed that toxicokinetic profiles of BDE209 could be described by the one-compartment model.In the higher dose group(500 ng/g wet weight),the calculated half-life(t1/2) and elimination rate(ke) were 17.7 d and 0.039/d in the liver,and 100.3 d and 0.007/d in the muscle,respectively.Three major methoxylated brominated diphenyl ethers(MeO-BDEs) were detected with 2,2’,4,4’-tetrabromo-5-methoxydiphenyl ether(5-MeO-BDE47) being detected in all tissue samples.There was no significant temporal change of 5-MeO-BDE47 concentration in the muscle,whereas an exponential increase was observed in the liver.Therefore,the metabolism rate of BDE209 depended on the administered dose.BDE209 was hardly accumulated in the muscle of rainbow trout,while the liver was a primary metabolic organ.MeO-BDEs were formed via metabolism of BDE209,which probably played a significant role in fish toxicology as a potential indicator.

  12. Biosorption and degradation of decabromodiphenyl ether by Brevibacillus brevis and the influence of decabromodiphenyl ether on cellular metabolic responses.

    Science.gov (United States)

    Wang, Linlin; Tang, Litao; Wang, Ran; Wang, Xiaoya; Ye, Jinshao; Long, Yan

    2016-03-01

    There is global concern about the effects of decabromodiphenyl ether (BDE209) on environmental and public health. The molecular properties, biosorption, degradation, accumulation, and cellular metabolic effects of BDE209 were investigated in this study to identify the mechanisms involved in the aerobic biodegradation of BDE209. BDE209 is initially absorbed by wall teichoic acid and N-acetylglucosamine side chains in peptidoglycan, and then, BDE209 is transported and debrominated through three pathways, giving tri-, hepta-, octa-, and nona-bromodiphenyl ethers. The C-C bond energies decrease as the number of bromine atoms on the diphenyl decreases. Polybrominated diphenyl ethers (PBDEs) inhibit protein expression or accelerate protein degradation and increase membrane permeability and the release of Cl(-), Na(+), NH4 (+), arabinose, proteins, acetic acid, and oxalic acid. However, PBDEs increase the amounts of K(+), Mg(2+), PO4 (3-), SO4 (2-), and NO3 (-) assimilated. The biosorption, degradation, accumulation, and removal efficiencies when Brevibacillus brevis (1 g L(-1)) was exposed to BDE209 (0.5 mg L(-1)) for 7 days were 7.4, 69.5, 16.3, and 94.6 %, respectively. PMID:26555880

  13. Oncogenic GNAQ and GNA11 mutations in uveal melanoma in Chinese.

    Directory of Open Access Journals (Sweden)

    Xiaolin Xu

    Full Text Available To examine whether GNAQ and GNA11 somatic mutations previously identified in uveal melanomas of Caucasians are associated with uveal melanomas in Chinese patients.Uveal melanomas treated by primary enucleation in Chinese patients underwent a mutation analysis of GNAQ and GNA11 with sequencing of exon 5 and exon 4.The study included 50 patients with uveal melanoma and with a mean age of 47.6±13.0 years. During the follow-up of at least 3 years, 20 (40% patients developed extraocular metastases. The frequencies of GNAQ and GNA11 somatic mutations in uveal melanoma were 18% (9/50 and 20% (10/50, respectively. The mutations occurred exclusively in codon 209 of exon 5. No mutations were detected in exon 4. Mutations affecting codon 209 in GNAQ were c.626A>C(Q209P (78% and c.626A>T(Q209L (22%. Mutations affecting codon 209 in GNA11 were exclusively c.626A>T(Q209L (100%. In none of the tumors, mutations of BRAF and NRAS were detected. GNAQ/11 mutations were marginally (P = 0.045 associated with optic disc involvement. In Kaplan-Meier analysis, metastasis-free survival was not significantly (P = 0.94 associated with GNAQ/11 mutations.Mutations of GNAQ and GNA11 can be found in Chinese patients as in Caucasian patients with uveal melanoma, with a higher frequency reported for Caucasian patients.

  14. Regional dynamics of persistent organic pollutants (POPs) in the Pearl River Delta, China: implications and perspectives.

    Science.gov (United States)

    Zhang, Kai; Zhang, Bao-Zhong; Li, Shao-Meng; Zeng, Eddy Y

    2011-10-01

    The mass transport budgets of 1,1,1-trichloro-2,2-bis(chlorophenyl)ethane (p,p'-DDT) and decabromodiphenyl ether (BDE-209) in the Pearl River Delta, South China were calculated based on previously collected data. Residual p,p'-DDT, mostly related to historical use, has largely settled into soil (780,000 kg), while the soil BDE-209 inventory (44,000 kg) is considerably smaller. Conversely, large amounts of BDE-209 currently used in numerous commercial products have resulted in a much higher atmospheric depositional flux of BDE-209 (28,100 kg/yr) relative to p,p'-DDT (310 kg/yr). The soil inventory of p,p'-DDT is predicted to decrease to half of its current value after 22 years, and the percent area containing soil p,p'-DDT at levels exceeding the effects range-medium (27 ng/g) will decrease from 40% to 20%. Finally, soil BDE-209 inventory will reach an equilibrium value of 940 tons in ~60 years, when BDE-209 levels in 50% of soil will be above an equivalent risk guideline value (125 ng/g).

  15. Long-term exposure to high levels of decabrominated diphenyl ether inhibits CD4 T-cell functions in C57Bl/6 mice.

    Science.gov (United States)

    Feng, Yan; Zeng, Weihong; Wang, Ying; Shen, Hao; Wang, Yan

    2016-09-01

    In recent years, the adverse health effects of decabrominated diphenyl ether (BDE-209) have raised more concerns as a growing number of studies reported its persistence in the environment and abundance in the human population, especially in occupational environmental compartments and exposed personnel. This study applies our previous animal model simulating occupational exposure to BDE-209 to investigate its potential adverse effects on CD4 T cells. Female C57Bl/6 mice were orally gavaged with BDE-209 at a dose of 800 mg kg(-1) every 2 days for 10 months and the blood of each mouse was collected for analysis. Kinetic changes of the peripheral immune system were investigated from 1 to 5 months of exposure. The chronic effects on cytokine production, proliferation and the antigen-specific responses of CD4 T cells were evaluated at 7, 9 and 10 months, respectively. The results have shown that impaired proliferation and cytokine (IFN-γ, IL-2 or TNF-α) production of CD4 T cells were observed in BDE-209-exposed mice, accompanied by increased T regulatory cells in the blood. BDE-209 exposure in vitro also suppressed the reactivity of CD4 T cells at concentrations of 0.01, 0.1, 1 and 10 μM. Furthermore, we observed weaker antigen-specific CD4 T-cell responses to Listeria monocytogenes infection in the mice exposed to BDE-209, suggesting decreased resistance to exogenous pathogens. Taken together, these observations indicate an impaired cellular immunity after long-term and relative high-dose exposure to BDE-209 in adult mice. Copyright © 2015 John Wiley & Sons, Ltd. PMID:26682527

  16. Estimating European historical production, consumption and atmospheric emissions of decabromodiphenyl ether

    Energy Technology Data Exchange (ETDEWEB)

    Earnshaw, Mark R., E-mail: m.earnshaw2@lancaster.ac.uk; Jones, Kevin C., E-mail: k.c.jones@lancaster.ac.uk; Sweetman, Andy J., E-mail: a.sweetman@lancaster.ac.uk

    2013-03-01

    A European scale production, consumption and environmental emissions inventory is produced for decabromodiphenyl ether (DecaBDE) for the period 1970–2020. A dynamic substance flow analysis model of DecaBDE is developed and emission of the main congener, BDE-209, to environmental compartments is estimated. From 1970 to 2010, it is estimated that a total of 185,000–250,000 tonnes of DecaBDE was consumed in Europe. Consumption peaked in the late 1990s at approximately 9000 tonnes/year and has declined by ∼ 30% in 2010. Predicted BDE-209 atmospheric emissions peak in 2004 at 10 tonnes/year. The waste management phase of the BDE-209 life cycle is responsible for the majority of atmospheric emissions via volatilisation and particle bound emissions from landfills, whilst leakage from Sewerage systems is the major source of emissions to the hydrosphere. Use of sewage sludge from wastewater treatment works as an agricultural fertiliser is the most important pathway of BDE-209 to soil. Although DecaBDE consumption has declined in recent years, the stock in use for 2010 remains considerable (60,000 tonnes) and is likely to act as a source of atmospheric emissions for several decades. Uncertainties exist in these estimations and more field or experimental data is needed to clarify the significance of certain emission pathways, in particular, emissions from landfill sites. - Highlights: ► Total DecaBDE consumption in Europe for the period 1970–2010 is estimated to be between 185,000 and 250,000 tonnes. ► European atmospheric emissions of BDE-209 is predicted to peak in 2004 at 10 tonnes/year. ► The waste management phase is responsible for the majority of BDE-209 environmental emissions. ► The volume of BDE-209 present in the anthroposphere is declining and is predicted to fall to negligible levels by 2030.

  17. Relationships between polybrominated diphenyl ethers and transcription and activity of type 1 deiodinase in a gull highly exposed to flame retardants.

    Science.gov (United States)

    François, Anthony; Técher, Romy; Houde, Magali; Spear, Philip; Verreault, Jonathan

    2016-09-01

    Deca-brominated diphenyl ether (deca-BDE), composed mainly of BDE-209, is subject to usage restrictions in North America and Europe, although global action on its continued use has yet to be undertaken. Relatively large concentrations of polybrominated diphenyl ethers (PBDEs), especially BDE-209 and its higher brominated degradation products, have been reported in tissues of ring-billed gulls (Larus delawarensis) breeding near the densely populated city of Montreal (QC, Canada). There is limited knowledge of BDE-209 biotransformation and toxicokinetics in birds. Deiodinases, a class of enzymes catalyzing thyroid hormone conversion, have been suggested to be involved in BDE-209 debromination in birds. The objective of the present study was to investigate the relationships between PBDE concentrations and type 1 deiodinase (D1) transcription and in vitro activity (microsomes) in livers of Montreal-breeding ring-billed gulls. The ring-billed gulls exhibiting the highest D1 activity in liver microsomes accumulated the greatest liver concentrations of hepta-BDEs and octa-BDEs. Activity of D1 was inversely related to concentration ratios of BDE-209 to octa-BDEs and ∑hepta-BDE. An even stronger inverse relation was found between D1 activity and BDE-209 to ∑nona + octa + hepta-BDE concentration ratios. The messenger ribonucleic acid (mRNA) levels of D1 in gull livers were inversely associated with liver concentrations of ∑octa-BDE. The present study's findings suggest that D1 is potentially involved in BDE-209 biotransformation and accumulation of higher brominated PBDEs in livers of ring-billed gulls. Environ Toxicol Chem 2016;35:2215-2222. © 2016 SETAC. PMID:27336952

  18. The effect of LED-light action on microbial colony forming ability of several species of staphylococcus

    Science.gov (United States)

    Tuchina, Elena S.; Permyakova, Natalia F.; Tuchin, Valery V.

    2007-05-01

    Photodynamic therapy (PDT) now is widespread for treatment of the various skin infections caused by Propionibacterium acnes or Staphylococcii spp. We used PDT for influence on opportunistic microflora of human skin presented by Staphylococcus hominis, S. warnery, S. epidermidis S. aureus 209 P, S. aureus 69. Species S. epidermidis, S. aureus 209 P, S. hominis to some extent reduced colonies forming ability under action of dual wavelength LED-light (442 nm and 597 nm). For species S. warnery, S. aureus 69 the increase in CFU number under action of light relative to control was characteristic. Our experiments have shown, that phototherapy can be used for treatment of diseases associated with S. aureus 209 P. The doze 8 J/cm2 caused reduction in CFU of this species on 40% relative to control.

  19. EST Table: AU004022 [KAIKOcDNA[Archive

    Lifescience Database Archive (English)

    Full Text Available AU004022 ws00847 10/09/28 81 %/249 aa ref|NP_001106136.1| Annexin IX isoform B [Bom...byx mori] dbj|BAA92810.1| annexin IX-B [Bombyx mori] 10/08/28 73 %/209 aa FBpp0280989|DpseGA19090-PA 10/08/2...7 43 %/209 aa T07C4.9a#CE23956#WBGene00003589#locus:nex- 2#Annexin#status:Confirmed#UniProt:Q27512#protein_i...ene:ANXB9 10/09/10 63 %/210 aa gnl|Amel|GB16448-PA 10/09/10 75 %/209 aa gi|91092420|ref|XP_967931.1| PREDICTED: similar to Annexin IX CG5730-PC [Tribolium castaneum] NM_001043376 ws0 ...

  20. Phosphorylation of ARD1 by IKKβ contributes to its destabilization and degradation

    International Nuclear Information System (INIS)

    IκB kinase β (IKKβ), a major kinase downstream of various proinflammatory signals, mediates multiple cellular functions through phosphorylation and regulation of its substrates. On the basis of protein sequence analysis, we identified arrest-defective protein 1 (ARD1), a protein involved in apoptosis and cell proliferation processes in many human cancer cells, as a new IKKβ substrate. We provided evidence showing that ARD1 is indeed a bona fide substrate of IKKβ. IKKβ physically associated with ARD1 and phosphorylated it at Ser209. Phosphorylation by IKKβ destabilized ARD1 and induced its proteasome-mediated degradation. Impaired growth suppression was observed in ARD1 phosphorylation-mimic mutant (S209E)-transfected cells as compared with ARD1 non-phosphorylatable mutant (S209A)-transfected cells. Our findings of molecular interactions between ARD1 and IKKβ may enable further understanding of the upstream regulation mechanisms of ARD1 and of the diverse functions of IKKβ.

  1. Study on Directional Paired Comparison Test of Vinegar%食醋定向成对比较检验研究

    Institute of Scientific and Technical Information of China (English)

    魏永义; 王富刚

    2016-01-01

    In this paper,directional paired comparison test method is adopted to evaluate the sensory properties of vinegar.The result shows that there's no significant difference in the intensity of saltiness,sweetness,scorch aroma and fruit aroma of two kinds of vinegar samples 375,209.There's significant difference in the intensity of color,sourness,umami and vinegar aroma of two kinds of vinegar samples.However,sample 375 is stronger than sample 209 in the intensity of color,sourness and vinegar aroma,and sample 209 is stronger than sample 375 in the intensity of umami.This method could evaluate the difference of certain sensory property of vinegar.%采用定向成对比较检验评价了食醋在感官特性上的差异,结果表明:在5%显著水平上,375和209两个食醋样品在咸味、甜味、焦香、果香的强度上无显著差异;两个食醋样品在色泽、酸味、鲜味、醋香的强度上有显著差异,但是,375样品比209样品的色泽、酸味、醋香都强,209样品比375样品的鲜味强,该方法能评价出食醋某一感官特性之间的差异。

  2. Study of Neutron-Deficient $^{202-205}$Fr Isotopes with Collinear Resonance Ionization Spectroscopy

    CERN Document Server

    De Schepper, Stijn; Cocolios, Thomas; Budincevic, Ivan

    The scope of this master’s thesis is the study of neutron-deficient $^{202−205}$Fr isotopes. These isotopes are inside the neutron-deficient lead region, a region that has shown evidence of shape coexistence. For this thesis, this discussion is limited to the phenomenon where a low lying excited state has a different shape than the ground state. Shape coexistence is caused by intruder states. These are single-particle Shell Model states that are perturbed in energy due to the interaction with a deformed core. In the neutron-deficient lead region the main proton intruder orbit is the 3s$_{1/2}$orbit. When going towards more neutron-deficient isotopes, deformation increases. The $\\pi3s_{1/2}$orbit will rise in energy and will eventually become the ground state in odd- A bismuth (Z=83) isotopes. It is also observed in odd-A astatine (Z=85) isotopes, already in less neutron-deficient nuclei. The same phenomenon is expected to be present francium (Z=87) isotopes already at $^{199}$Fr. Although it is currently ...

  3. The biokinetics of alpha-particle emitting radiopharmaceuticals

    Energy Technology Data Exchange (ETDEWEB)

    Taylor, D.M. [School of Chemistry, Cardiff Univ., Cardiff (United Kingdom); Duffield, J.R. [Faculty of Applied Sciences, Univ. of the West of England, Bristol (United Kingdom)

    2005-07-01

    The past two decades have seen wide interest in the application of alpha-particle emitting radionuclides for targeted endoradiotherapy and a large number of compounds labeled with {sup 211}At (T{sup 1}/{sub 2} 7.21 h), {sup 212}Bi (T{sup 1}/{sub 2} 1 h) or {sup 213}Bi (T{sup 1}/{sub 2} 0.78 h) have been studied. Knowledge of the biokinetic behaviour of such agents is important both for their optimal clinical exploitation and for general radiological protection purposes. Animal studies of the distribution and retention of {sup 211}At compounds, including ionic astatide, substituted aromatic compounds and labelled monoclonal antibodies, have provided new information on the biochemistry of astatine. With respect the thyroid gland the uptake of the astatide ion has been shown to be very much lower than that of the iodide ion. Less information is available for {sup 212}Bi-labelled radiopharmaceuticals. The available data for both {sup 211}At and {sup 212}Bi radiopharmaceuticals are reviewed. Cautious generic biokinetic models for inorganic and simple organic compounds of {sup 211}At and {sup 212}Bi; for [{sup 211}At]-, and [{sup 212}Bi]-biphosphonates and for [{sup 211}At]-, and [{sup 212}Bi]-monoclonal antibodies, are proposed for use in general radiological protection when compound-specific data are not available. (orig.)

  4. Combined effect of gefitinib ('Iressa', ZD1839) and targeted radiotherapy with {sup 211}At-EGF

    Energy Technology Data Exchange (ETDEWEB)

    Sundberg, Aasa Liljegren; Orlova, Anna; Gedda, Lars; Tolmachev, Vladimir; Carlsson, Joergen [Division of Biomedical Radiation Sciences, Rudbeck Laboratory, Uppsala University, 751 85, Uppsala (Sweden); Almqvist, Ylva [Division of Radiology, Uppsala University, Uppsala (Sweden); Blomquist, Erik [Division of Oncology, Uppsala University, Uppsala (Sweden); Jensen, Holger J. [Department of Clinical Physiology and Nuclear Medicine, PET and Cyclotron Unit, Rigshospitalet, Copenhagen (Denmark)

    2003-10-01

    The EGFR-TKI (epidermal growth factor receptor tyrosine kinase inhibitor) gefitinib ['Iressa' (trademark of the AstraZeneca group of companies), ZD1839] increases the cellular uptake of radiolabelled epidermal growth factor (EGF). We investigated gefitinib treatment combined with astatine-211 EGF targeting in vitro using two cell lines expressing high levels of EGFR: A431 (sensitive to gefitinib) and U343MGaCl2:1 (resistant to gefitinib). In both cell lines, the uptake of {sup 211}At-EGF was markedly increased by concomitant treatment with gefitinib. Survival was investigated using both a clonogenic survival assay and a cell growth assay. Combined gefitinib and {sup 211}At-EGF treatment reduced the survival of U343 cells 3.5-fold compared with {sup 211}At-EGF alone. In A431 cells, {sup 211}At-EGF treatment resulted in very low survival, but combined treatment with gefitinib increased the survival by about 20-fold. These results indicate that combined treatment with gefitinib might increase the effect of ligand-mediated radionuclide therapy in gefitinib-resistant tumours and decrease the effect of such therapy in gefitinib-sensitive tumours. (orig.)

  5. Alpha particle emitters in medicine

    International Nuclear Information System (INIS)

    Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical applications of alpha emitters. In recent years, however, the potential use of antibodies labeled with alpha emitting radionuclides against cancer has seemed promising because alpha particles are highly effective in cell killing. High dose rates at high LET, effectiveness under hypoxic conditions, and minimal expectancy of repair are additional advantages of alpha emitters over antibodies labeled with beta emitting radionuclides for cancer therapy. Cyclotron-produced astatine-211 (211At) and natural bismuth-212 (212Bi) have been proposed and are under extensive study in the United States and Europe. Radium-223 (223Ra) also has favorable properties as a potential alpha emitting label, including a short-lived daughter chain with four alpha emissions. The radiation dosimetry of internal alpha emitters is complex due to nonuniformly distributed sources, short particle tracks, and high relative specific ionization. The variations in dose at the cellular level may be extreme. Alpha-particle radiation dosimetry, therefore, must involve analysis of statistical energy deposition probabilities for cellular level targets. It must also account fully for nonuniform distributions of sources in tissues, source-target geometries, and particle-track physics. 18 refs., 4 figs

  6. Tumor Immunotargeting Using Innovative Radionuclides

    Directory of Open Access Journals (Sweden)

    Françoise Kraeber-Bodéré

    2015-02-01

    Full Text Available This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality.

  7. Development of Reagents for Application of At-211 to Targeted Radionuclide Therapy of Cancer

    Energy Technology Data Exchange (ETDEWEB)

    Wilbur, D. Scott

    2011-12-23

    This grant covered only a period of 4 months as the major portion of the award was returned to DOE due to an award of funding from NIH that covered the same research objectives. A letter regarding the termination of the research is attached as the last page of the Final Report. The research conducted was limited due to the short period of this grant, but the results obtained in that period are outlined in the Final Report. The studies addressed in the research effort were directed at a problem that is of critical importance to the in vivo application of the alpha-particle emitting radionuclide At-211. That problem, low in vivo stability of many astatinated molecules, severely limits the use of At-211 in therapeutic applications. The advances sought in the studies were expected to expand the types of biomolecules that can be used as carriers of At-211, and provide improved in vivo targeting of the radiation dose compared with the dose delivered to normal tissue.

  8. Tumor immunotargeting using innovative radionuclides.

    Science.gov (United States)

    Kraeber-Bodéré, Françoise; Rousseau, Caroline; Bodet-Milin, Caroline; Mathieu, Cédric; Guérard, François; Frampas, Eric; Carlier, Thomas; Chouin, Nicolas; Haddad, Ferid; Chatal, Jean-François; Faivre-Chauvet, Alain; Chérel, Michel; Barbet, Jacques

    2015-01-01

    This paper reviews some aspects and recent developments in the use of antibodies to target radionuclides for tumor imaging and therapy. While radiolabeled antibodies have been considered for many years in this context, only a few have reached the level of routine clinical use. However, alternative radionuclides, with more appropriate physical properties, such as lutetium-177 or copper-67, as well as alpha-emitting radionuclides, including astatine-211, bismuth-213, actinium-225, and others are currently reviving hopes in cancer treatments, both in hematological diseases and solid tumors. At the same time, PET imaging, with short-lived radionuclides, such as gallium-68, fluorine-18 or copper-64, or long half-life ones, particularly iodine-124 and zirconium-89 now offers new perspectives in immuno-specific phenotype tumor imaging. New antibody analogues and pretargeting strategies have also considerably improved the performances of tumor immunotargeting and completely renewed the interest in these approaches for imaging and therapy by providing theranostics, companion diagnostics and news tools to make personalized medicine a reality. PMID:25679452

  9. SPECT assay of radiolabeled monoclonal antibodies. Progress report, September 1, 1992--August 24, 1993

    Energy Technology Data Exchange (ETDEWEB)

    Jaszczak, R.J.

    1993-08-20

    The overall goal of this project is to improve the effectiveness of single photon emission computed tomography (SPECT) to image and quantify radiolabeled monoclonal antibodies. During the past year, we have made significant progress toward this goal, and this report summarizes that work. Our efforts have been mainly directed along three fronts. First, we have developed and tested new reconstruction methods including three-dimensional iterative algorithms that model non-uniform attenuation and distance-dependent detector response. Both fan beam and parallel beam collimator geometries have been modeled and novel ways of improving the efficiency of the computationally intensive methods have been introduced. Second, an ultra-high resolution, small field-of-view pinhole collimator has been constructed and evaluated. Reconstructed spatial resolution of 1 to 3 mm (FWHM) has been achieved in phantom scans with a useful field-of-view of 9 to 10 cm. Finally, we have investigated the ability of SPECT to image and quantify astatine-211 distributions. Reconstructed images of phantom data demonstrated quantitative accuracy to within 10% with proper attenuation and scatter compensation.

  10. Silver impregnated nanoparticles of titanium dioxide as carriers for {sup 211}At

    Energy Technology Data Exchange (ETDEWEB)

    Cedrowska, Edyta; Lyczko, Monika; Piotrowska, Agata; Bilewicz, Aleksander [Institute of Nuclear Chemistry and Technology, Warsaw (Poland); Stolarz, Anna; Trcinska, Agnieszka [Warsaw Univ. (Poland). Heavy Ion Lab.; Szkliniarz, Katarzyna [Silesia Univ. Katowice (Poland). Inst. of Physics; Was, Bogdan [Polish Academy of Science, Cracow (Poland). Inst. of Nuclear Physics

    2016-08-01

    The {sup 211}At radioisotope exhibits very attractive nuclear properties for application in radionuclide therapy. Unfortunately use of {sup 211}At is limited, because astatine as the heaviest halogen forms weak bond with carbon atoms in the biomolecules which makes {sup 211}At bioconjugates unstable in physiological conditions. In our work we propose a new solution for binding of {sup 211}At which consists of using nanoparticles of titanium dioxide modified with silver atoms as carriers for {sup 211}At. Ag{sup +} cations have been absorbed on the nanometer-sized TiO{sub 2} particles (15 and 32 nm) through ion exchange process and were reduced in Tollens' reaction. The obtained TiO{sub 2}-Ag nanoparticles were labeled with {sup 211}At. It was found that labeling yields were almost quantitative under reducing conditions, while under oxidizing conditions they dropped to about 80%. The labeled nanoparticles exhibited very high stability in physiological salt, PBS buffer, solutions of peptides (0.001 M cysteine, 0.001 M glutathione) and in human blood serum. To make TiO{sub 2}/Ag nanoparticles well dispersed in water and biocompatible their surface was modified with a silane coupling agent containing poly(ethyleneglycol) molecules. The developed functionalization approach will allow us to attach biomolecules to the TiO{sub 2}/Ag surface.

  11. Nuclear and chemical data for life sciences

    International Nuclear Information System (INIS)

    Use of reactor produced radionuclides is popular in life sciences. However, cyclotron production of proton rich radionuclides are being more focused in recent times. These radionuclides have already gained attention in various fields, including life sciences, provided they are obtained in pure form. This article is a representative brief of our contributions in generating nuclear data for the production of proton rich radionuclides of terbium, astatine, technetium, ruthenium, cadmium, niobium, zirconium, rhenium, etc., which may have application in clinical, biological, agriculture studies or in basic research. The chemical data required to separate the product isotopes from the corresponding target matrix have been presented along with a few propositions of radiopharmaceuticals. It also emphasizes on the development of simple empirical technique, based on the nuclear reaction model analysis, to generate reliable nuclear data for the estimation of yield and angular distribution of emitted neutrons and light charged particles from light as well as heavy ion induced reactions on thick stopping targets. These data bear utmost important in radiation dosimetry. (author)

  12. Studies of Stable Octupole Deformations in the Radium Region

    CERN Multimedia

    2002-01-01

    The purpose of the present project is to locate and identify states in the atomic nuclei possessing stable pearshaped octupole deformation. Such states, formally related to the structures known in molecular physics, manifest themselves as families of parity doublets in odd nuclei.\\\\ \\\\ The best possibilities for observing stable octupole deformations are offered in the Ra-region. Both theoretical calculations and experimental indications support such expectations. Such indications are the non-observation of two-phonon octupole vibrational states in the ISOLDE studies of the even-even radium nuclei, and the reversed sign of the decoupling factor of the ground state band in |2|2|5Ra observed in the single-neutron transfer reactions. In order to establish the predicted strong E1 and E3-transitions between the parity doublets in odd nuclei with stable octupole deformations it is proposed to study conversion electrons in odd-mass francium radium and radon isotopes following the @b-decay of francium and astatine. \\...

  13. Alpha particle emitters in medicine

    Energy Technology Data Exchange (ETDEWEB)

    Fisher, D.R.

    1989-09-01

    Radiation-induced cancer of bone, liver and lung has been a prominent harmful side-effect of medical applications of alpha emitters. In recent years, however, the potential use of antibodies labeled with alpha emitting radionuclides against cancer has seemed promising because alpha particles are highly effective in cell killing. High dose rates at high LET, effectiveness under hypoxic conditions, and minimal expectancy of repair are additional advantages of alpha emitters over antibodies labeled with beta emitting radionuclides for cancer therapy. Cyclotron-produced astatine-211 ({sup 211}At) and natural bismuth-212 ({sup 212}Bi) have been proposed and are under extensive study in the United States and Europe. Radium-223 ({sup 223}Ra) also has favorable properties as a potential alpha emitting label, including a short-lived daughter chain with four alpha emissions. The radiation dosimetry of internal alpha emitters is complex due to nonuniformly distributed sources, short particle tracks, and high relative specific ionization. The variations in dose at the cellular level may be extreme. Alpha-particle radiation dosimetry, therefore, must involve analysis of statistical energy deposition probabilities for cellular level targets. It must also account fully for nonuniform distributions of sources in tissues, source-target geometries, and particle-track physics. 18 refs., 4 figs.

  14. Structural relaxation monitored by instantaneous shear modulus

    DEFF Research Database (Denmark)

    Olsen, Niels Boye; Dyre, Jeppe; Christensen, Tage Emil

    1998-01-01

    time definition based on a recently proposed expression for the relaxation time, where G [infinity] reflects the fictive temperature. All parameters entering the reduced time were determined from independent measurements of the frequency-dependent shear modulus of the equilibrium liquid.......This paper reports on aging of the silicone oil MS704 for sudden changes of temperature from 210.5 to 209.0 K and from 207.5 to 209.0 K studied by continuously monitoring the instantaneous shear modulus G [infinity]. The results are interpreted within the Tool-Narayanaswamy formalism with a reduced...

  15. Polybrominated diphenyl ethers in paired samples of maternal and umbilical cord blood plasma and associations with house dust in a Danish cohort

    DEFF Research Database (Denmark)

    Frederiksen, Marie; Thomsen, Cathrine; Frøshaug, May;

    2010-01-01

    determined in placental tissue from the same individuals, and the relationship with the external exposure from house dust from the participants' homes was explored. Samples of maternal and umbilical cord plasma from a cohort of 51 pregnant women from the Copenhagen area were collected. Paired maternal...... and umbilical cord plasma were analysed for BDE-28, 37, 47, 85, 99, 100, 119, 138, 153, 154, 183, 209 and the brominated biphenyl BB-153 using automated SPE extraction and GC-HRMS for the tri- to hepta-BDEs and GC-LRMS (ECNI) for BDE-209. PBDEs were detected in all maternal and umbilical cord plasma samples...

  16. AcEST: BP916259 [AcEST

    Lifescience Database Archive (English)

    Full Text Available |YN02_CAEEL Uncharacterized protein T23G5.2 OS=Caenorha... 41 0.002 sp|Q757H2|CSR1..._ASHGO Phosphatidylinositol transfer protein CSR1 ... 41 0.002 sp|Q9VMD6|RETM_DROME Protein real-time OS=Dr...|O66585|Y209_AQUAE Uncharacterized protein aq_209 OS=Aquifex a... 37 0.032 sp|Q06705|CSR1_YEAST Phosphatidyl...inositol transfer protein CSR1 ... 35 0.16 sp|P41034|TTPA_RAT Alpha-tocopherol transfer protein OS=Rattus n.

  17. Commissioning of the Francium Trapping Facility at TRIUMF

    CERN Document Server

    Tandecki, M; Collister, R; Aubin, S; Behr, J A; Gomez, E; Gwinner, G; Orozco, L A; Pearson, M R

    2013-01-01

    We report on the successful commissioning of the Francium Trapping Facility at TRIUMF. Large laser-cooled samples of francium are produced from a francium ion beam delivered by the ISAC radioactive ion beam facility. The ion beam is neutralized on an yttrium foil, which is subsequently heated to transfer the atoms into the magneto-optical trapping region. We have successfully trapped $^{207}$Fr, $^{209}$Fr and $^{221}$Fr, with a maximum of $2.5 \\times 10^5$ $^{209}$Fr atoms. The neutral cold atoms will be used in studies of the weak interaction through measurements of atomic parity non-conservation.

  18. Effects of humic acids and microorganisms on decabromodiphenyl ether, 4,4′-dibromodiphenyl ether and anthracene transportation in soil

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    In this study, effects of humic acids (HA) and microorganisms on the migration of hydrophobic organic contaminants (HOCs), decabromodiphenyl ether (BDE-209), 4,4′-dibromodiphenyl ether (BDE-15) and anthracene, in soils were examined. More soil particles were dispersed into the colloidal phase (0.22-1 μm) in the presence of HA and/or microorganisms as a result of increased erosion and friction. The study suggested that PBDEs (BDE-209 and BDE-15) and anthracene in soils would be transported to other places by soil colloids with surface and underground water flow given the high concentrations of HA and microorganisms in the natural environment.

  19. Creating a system of medical and psychological rehabilitation of extreme professions representatives (firemen-rescuers as a model)

    OpenAIRE

    Chumaeva, Julia; Golikovа, Vladislava; Nekhoroshkova, Julia; Ogulenko, Alexey; Shafran, Leonid

    2015-01-01

    Chumaeva Julia, Golikovа Vladislava, Nekhoroshkova Julia, Ogulenko Alexey, Shafran Leonid. Creating a system of medical and psychological rehabilitation of extreme professions representatives (firemen-rescuers as a model). Journal of Education, Health and Sport. 2015;5(8):197-209. ISSN 2391-8306. DOI 10.5281/zenodo.28064 http://dx.doi.org/10.5281/zenodo.28064 http://ojs.ukw.edu.pl/index.php/johs/article/view/2015%3B5%288%29%3A197-209 https://pbn.nauka.gov.pl/works/6...

  20. Patterns and concentration levels of polybrominated diphenyl ethers (PBDEs) in placental tissue of women in Denmark

    DEFF Research Database (Denmark)

    Frederiksen, Marie; Thomsen, Marianne; Vorkamp, Katrin;

    2009-01-01

    The levels and congener patterns of PBDEs were investigated in human placental samples in Denmark. The median concentrations of sigmaPBDE(tri-hepta) and BDE-209 in the 50 samples were 1.22 and 1.14 ng g(-1) lw, respectively, with the total sum ranging from 0.51 to 17.1 ng g(-1) lw, which is similar...... index (BMI), revealed inherent congener patterns (19% X-variance) showing increased frequency for participants within the highest BMI group to have elevated concentrations of BDE-209 in the placental tissue....

  1. A Swedish family with de novo alpha-synuclein A53T mutation: evidence for early cortical dysfunction

    DEFF Research Database (Denmark)

    Puschmann, Andreas; Ross, Owen A; Vilariño-Güell, Carles;

    2009-01-01

    A de novo alpha-synuclein A53T (p.Ala53 Th; c.209G > A) mutation has been identified in a Swedish family with autosomal dominant Parkinson's disease (PD). Two affected individuals had early-onset (before 31 and 40 years), severe levodopa-responsive PD with prominent dysphasia, dysarthria, and...

  2. [Christofer Herrmann. Kloster und Burg - die architektur des Deutschens Ordens im Pressen und Livland. In : Glaube, Macht und Pracht. GeistlicheGemeinschaften des Ostseeraums im Zeitalter der Backsteingotik] / Dennis Hortmuth

    Index Scriptorium Estoniae

    Hortmuth, Dennis

    2011-01-01

    Arvustus: Christofer Herrmann. Kloster und Burg - die Architektur des Deutschen Ordens in Preussen und Livland. In : Glaube, Macht und Pracht. GeistlicheGemeinschaften des Ostseeraums im Zeitalter der Backsteingotik (=Archäologie und Geschichte im Ostseeraum; Archaeology and History of the Baltic 6) Rahden : Verlag Marie Leidorf, 2009. S. 209-219. Saksa Ordu arhitektuurist Preisi- ja Liivimaal

  3. 77 FR 72851 - California State Nonroad Engine Pollution Control Standards; Portable Equipment Registration...

    Science.gov (United States)

    2012-12-06

    ... procedures are consistent with section 209 of the Act. \\23\\ 76 FR 7194 (February 9, 2011). In response to EPA... Act (``CAA'' or ``the Act''), regarding its Portable Equipment Registration Program (``PERP'').\\1\\ The..., without prejudice to CARB's position and to avoid further delay in obtaining federal authorization,...

  4. 77 FR 38771 - Prospective Grant of Exclusive Patent License

    Science.gov (United States)

    2012-06-29

    ... National Institute of Standards and Technology Prospective Grant of Exclusive Patent License AGENCY... of exclusive patent license. SUMMARY: This is a notice in accordance with 35 U.S.C. 209(e) and 37 CFR... territories, possessions and commonwealths, to NIST's interest in the invention embodied in U.S....

  5. 77 FR 48130 - Prospective Grant of Exclusive Patent License

    Science.gov (United States)

    2012-08-13

    ... National Institute of Standards and Technology Prospective Grant of Exclusive Patent License AGENCY... patent license. SUMMARY: This is a notice in accordance with 35 U.S.C. 209(e) and 37 CFR 404.7(a)(1)(i... and commonwealths, to NIST's interest in the invention embodied in Provisional Application for...

  6. 75 FR 63443 - Prospective Grant of Exclusive Patent License

    Science.gov (United States)

    2010-10-15

    ... National Institute of Standards and Technology Prospective Grant of Exclusive Patent License AGENCY... patent license. SUMMARY: This is a notice in accordance with 35 U.S.C. 209(c)(1) and 37 CFR 404.7(a)(1)(i... and commonwealths, to NIST's interest in the invention embodied in U.S. Patent Application No....

  7. 77 FR 65673 - Prospective Grant of Exclusive Patent License

    Science.gov (United States)

    2012-10-30

    ... National Institute of Standards and Technology Prospective Grant of Exclusive Patent License AGENCY... patent license. SUMMARY: This is a notice in accordance with 35 U.S.C. 209(e) and 37 CFR 404.7(a)(1)(i... and commonwealths, to NIST's interest in the invention embodied in U.S. Patent Application No....

  8. Brief Report: Are Autistic-Behaviors in Children Related to Prenatal Vitamin Use and Maternal Whole Blood Folate Concentrations?

    Science.gov (United States)

    Braun, Joseph M.; Froehlich, Tanya; Kalkbrenner, Amy; Pfeiffer, Christine M.; Fazili, Zia; Yolton, Kimberly; Lanphear, Bruce P.

    2014-01-01

    Prenatal multivitamin/folic acid supplement use may reduce the risk of autism spectrum disorders. We investigated whether 2nd trimester prenatal vitamin use and maternal whole blood folate (WBF) concentrations were associated with Social Responsiveness Scale (SRS) scores at 4-5 years of age in a prospective cohort of 209 mother-child pairs. After…

  9. Dysthymia among Substance Abusers: An Exploratory Study of Individual and Mental Health Factors

    Science.gov (United States)

    Diaz, Naelys; Horton, Eloise G.; McIlveen, John; Weiner, Michael; Nelson, Jenniffer

    2009-01-01

    The purpose of this study was to examine the individual characteristics and mental health factors of dysthymic and nondysthymic substance abusers. Out of a total of 1,209 medical records reviewed to select cases of dysthymic and nondysthymic substance abusers attending a community drug treatment program, 183 medical records were selected, 48% of…

  10. Kvaalide kvainimine / Daniel C. Dennett ; tõlk. Bruno Mölder

    Index Scriptorium Estoniae

    Dennett, Daniel C., 1942-

    1997-01-01

    Järgneb Akadeemia 1998, nr. 1, lk. 189-221. Lk. 209-221 järelsõna: B. Mölder. Dennett ja kvaalid. Sisald. bibliogr. Tõlke allikas: Quining Qualia. In: Conciousness in Contemporary Science. - Oxford, 1988, lk. 42-77

  11. 48 CFR 234.004 - Acquisition strategy.

    Science.gov (United States)

    2010-10-01

    ... 48 Federal Acquisition Regulations System 3 2010-10-01 2010-10-01 false Acquisition strategy. 234..., DEPARTMENT OF DEFENSE SPECIAL CATEGORIES OF CONTRACTING MAJOR SYSTEM ACQUISITION 234.004 Acquisition strategy. (1) See 209.570 for policy applicable to acquisition strategies that consider the use of lead...

  12. The influence of temperature on photosynthesis of different tomato genotypes

    NARCIS (Netherlands)

    Gosiewski, W.; Nilwik, H.J.M.; Bierhuizen, J.F.

    1982-01-01

    Net photosynthesis and dark respiration from whole plants of various tomato genotypes were measured in a closed system. At low irradiance (27 W m−2) and low external CO2 concentration (550 mg m−3), net photosynthesis of 10 genotypes was found to vary between 0.122 and 0.209 mg CO2 m−2 s−1. Correlati

  13. 47 CFR 20.6 - CMRS spectrum aggregation limit.

    Science.gov (United States)

    2010-10-01

    ... any right to determine how the stock will be voted. Holdings by investment companies will be... telephone company, or a business owned by minorities and/or women, as these terms are defined in § 1.2110 of...) regulated as CMRS (see 47 CFR 20.9) shall have an attributable interest in a total of more than 55 MHz...

  14. Birth Order, Family Size, and Self-Esteem: A Filipino Study.

    Science.gov (United States)

    Watkins, David; Astilla, Estela

    1980-01-01

    Investigates the relationship between birth order and self-esteem among 209 11- to 13-year-old girls attending a private high school in the central Philippines. The Self-Esteem Inventory was used to measure self-esteem. No evidence of any influence of birth order, family size, or their interaction with self-esteem was found. (Author/RH)

  15. El desarrollo del aprendizaje significativo en el estudiante del curso de Matemáticas I de bachillerato, mediante el uso del texto álgebra interactiva.-única

    OpenAIRE

    Palazuelos Barranco, María del Socorro

    1999-01-01

    Tesis (Maestra en Educación, Especialidad en Desarrollo Cognitivo)--Instituto Tecnológico y de Estudios Superiores de Monterrey Universidad Virtual. Dra. Mónica Pórres Hernández, Asesor. Bibliografía: h. 209-210. Desc. física: viii, 211 h. : il. ; 28 cm.

  16. Single and multi-photon events with missing energy in $e^+ e^-$ collisions at 161 GeV < $\\sqrt{s}$ < 172 GeV

    CERN Document Server

    Acciarri, M; Aguilar-Benítez, M; Ahlen, S P; Alcaraz, J; Alemanni, G; Allaby, James V; Aloisio, A; Alverson, G; Alviggi, M G; Ambrosi, G; Anderhub, H; Andreev, V P; Angelescu, T; Anselmo, F; Arefev, A; Azemoon, T; Aziz, T; Bagnaia, P; Baksay, L; Banerjee, S; Banerjee, Sw; Banicz, K; Barczyk, A; Barillère, R; Barone, L; Bartalini, P; Baschirotto, A; Basile, M; Battiston, R; Bay, A; Becattini, F; Becker, U; Behner, F; Berdugo, J; Berges, P; Bertucci, B; Betev, B L; Bhattacharya, S; Biasini, M; Biland, A; Bilei, G M; Blaising, J J; Blyth, S C; Bobbink, Gerjan J; Böck, R K; Böhm, A; Boldizsar, L; Borgia, B; Bourilkov, D; Bourquin, Maurice; Braccini, S; Branson, J G; Brigljevic, V; Brock, I C; Buffini, A; Buijs, A; Burger, J D; Burger, W J; Busenitz, J K; Button, A M; Cai, X D; Campanelli, M; Capell, M; Cara Romeo, G; Carlino, G; Cartacci, A M; Casaus, J; Castellini, G; Cavallari, F; Cavallo, N; Cecchi, C; Cerrada-Canales, M; Cesaroni, F; Chamizo-Llatas, M; Chang, Y H; Chaturvedi, U K; Chekanov, S V; Chemarin, M; Chen, A; Chen, G; Chen, G M; Chen, H F; Chen, H S; Chéreau, X J; Chiefari, G; Chien, C Y; Cifarelli, Luisa; Cindolo, F; Civinini, C; Clare, I; Clare, R; Cohn, H O; Coignet, G; Colijn, A P; Colino, N; Commichau, V; Costantini, S; Cotorobai, F; de la Cruz, B; Csilling, Akos; Dai, T S; D'Alessandro, R; De Asmundis, R; Degré, A; Deiters, K; Della Volpe, D; Denes, P; De Notaristefani, F; DiBitonto, Daryl; Diemoz, M; Van Dierendonck, D N; Di Lodovico, F; Dionisi, C; Dittmar, Michael; Dominguez, A; Doria, A; Dova, M T; Duchesneau, D; Duinker, P; Durán, I; Dutta, S; Easo, S; Efremenko, Yu V; El-Mamouni, H; Engler, A; Eppling, F J; Erné, F C; Ernenwein, J P; Extermann, Pierre; Fabre, M; Faccini, R; Falciano, S; Favara, A; Fay, J; Fedin, O; Felcini, Marta; Fenyi, B; Ferguson, T; Ferroni, F; Fesefeldt, H S; Fiandrini, E; Field, J H; Filthaut, Frank; Fisher, P H; Fisk, I; Forconi, G; Fredj, L; Freudenreich, Klaus; Furetta, C; Galaktionov, Yu; Ganguli, S N; García-Abia, P; Gau, S S; Gentile, S; Gheordanescu, N; Giagu, S; Goldfarb, S; Goldstein, J; Gong, Z F; Gougas, Andreas; Gratta, Giorgio; Grünewald, M W; Gupta, V K; Gurtu, A; Gutay, L J; Hartmann, B; Hasan, A; Hatzifotiadou, D; Hebbeker, T; Hervé, A; Van Hoek, W C; Hofer, H; Hong, S J; Hoorani, H; Hou, S R; Hu, G; Innocente, Vincenzo; Jenkes, K; Jin, B N; Jones, L W; de Jong, P; Josa-Mutuberria, I; Kasser, A; Khan, R A; Kamrad, D; Kamyshkov, Yu A; Kapustinsky, J S; Karyotakis, Yu; Kaur, M; Kienzle-Focacci, M N; Kim, D; Kim, D H; Kim, J K; Kim, S C; Kim, Y G; Kinnison, W W; Kirkby, A; Kirkby, D; Kirkby, Jasper; Kiss, D; Kittel, E W; Klimentov, A; König, A C; Kopp, A; Korolko, I; Koutsenko, V F; Krämer, R W; Krenz, W; Kunin, A; Ladrón de Guevara, P; Laktineh, I; Landi, G; Lapoint, C; Lassila-Perini, K M; Laurikainen, P; Lebeau, M; Lebedev, A; Lebrun, P; Lecomte, P; Lecoq, P; Le Coultre, P; Le Goff, J M; Leiste, R; Leonardi, E; Levchenko, P M; Li Chuan; Lin, C H; Lin, W T; Linde, Frank L; Lista, L; Liu, Z A; Lohmann, W; Longo, E; Lu, W; Lü, Y S; Lübelsmeyer, K; Luci, C; Luckey, D; Luminari, L; Lustermann, W; Ma Wen Gan; Maity, M; Majumder, G; Malgeri, L; Malinin, A; Maña, C; Mangeol, D J J; Mangla, S; Marchesini, P A; Marin, A; Martin, J P; Marzano, F; Massaro, G G G; McNally, D; McNeil, R R; Mele, S; Merola, L; Meschini, M; Metzger, W J; Von der Mey, M; Mi, Y; Mihul, A; Van Mil, A J W; Mirabelli, G; Mnich, J; Molnár, P; Monteleoni, B; Moore, R; Morganti, S; Moulik, T; Mount, R; Müller, S; Muheim, F; Muijs, A J M; Nahn, S; Napolitano, M; Nessi-Tedaldi, F; Newman, H; Niessen, T; Nippe, A; Nisati, A; Nowak, H; Oh, Yu D; Opitz, H; Organtini, G; Ostonen, R; Palomares, C; Pandoulas, D; Paoletti, S; Paolucci, P; Park, H K; Park, I H; Pascale, G; Passaleva, G; Patricelli, S; Paul, T; Pauluzzi, M; Paus, C; Pauss, Felicitas; Peach, D; Pei, Y J; Pensotti, S; Perret-Gallix, D; Petersen, B; Petrak, S; Pevsner, A; Piccolo, D; Pieri, M; Pinto, J C; Piroué, P A; Pistolesi, E; Plyaskin, V; Pohl, M; Pozhidaev, V; 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    1997-01-01

    A search for single and multi-photon events with missing energy is performed using data collected at centre-of-mass energies between 161 GeV and 172 GeV for a total of 20.9 pb$^{-1}$ of integrated luminosity. The results obtained are used to derive the value for the $\

  17. 77 FR 20388 - California State Nonroad Engine Pollution Control Standards; Large Spark-Ignition (LSI) Engines...

    Science.gov (United States)

    2012-04-04

    ... context of section 209(b) motor vehicle waivers).\\7\\ \\5\\ 59 FR 36969 (July 20, 1994). \\6\\ See 62 FR 67733... increased risk of burn or fire) associated with compliance with the California standard. \\7\\ See 59 FR 36969... the issues raised by A4A. \\32\\ See, e.g., 74 FR 32744, 32783 (July 8, 2009). \\33\\ See Motor...

  18. Profiling the Jazz Singer

    Science.gov (United States)

    Hargreaves, Wendy

    2013-01-01

    This paper presents new data extracted from the National Survey of Jazz Instrumentalists and Vocalists. The survey was administered to 209 professional jazz musicians who resided and performed in Australia during 2009-2010. Presented here are five statistically significant characteristics which differentiate vocalists' experiences from other…

  19. Prevalence of impaired glucose tolerance and other types of dysglycaemia among young twins and singletons in Guinea-Bissau

    DEFF Research Database (Denmark)

    Hennild, Ditte Egegaard; Bjerregaard-Andersen, Morten; Joaquím, Luis Carlos;

    2016-01-01

    was conducted from February 2011 until March 2012 at the Bandim Health Project, a health and demographic surveillance system site in the capital Bissau. Twins (n = 209) and singletons (n = 182) were recruited from a previously established cohort. Oral glucose tolerance tests (OGTT) were performed, along...

  20. Fresh Fruit and Vegetable Purchases in an Urban Supermarket by Low-Income Households

    Science.gov (United States)

    Phipps, Etienne J.; Stites, Shana D.; Wallace, Samantha L.; Braitman, Leonard E.

    2013-01-01

    Objective: To investigate the predictors of fresh fruit and vegetable purchases in a low-income population and identify subgroups in which interventions to increase such purchases might prove useful. Methods: Retrospective analysis of 209 shopping transactions from 30 households. Individual and household characteristics obtained from primary…