WorldWideScience

Sample records for assessment los reales

  1. Los Alamos National Laboratory's Mobile Real Time Radiography System

    International Nuclear Information System (INIS)

    Vigil, J.; Taggart, D.; Betts, S.; Mendez, J.; Rael, C.; Martinez, F.

    1997-01-01

    A 450-KeV Mobile Real Time Radiography (RTR) System was delivered to Los Alamos National Laboratory (LANL) in January 1996. It was purchased to inspect containers of radioactive waste produced at (LANL). Since its delivery it has been used to radiograph greater than 600 drums of radioactive waste at various LANL sites. It has the capability of inspecting waste containers of various sizes. It has three independent X-Ray acquisition formats. The primary system used is a 12 in. image intensifier, the second is a 36 in. linear diode array (LDA) and the last is an open system. It is fully self contained with on board generator, HVAC and a fire suppression system. It is on a 53 ft long X 8 ft. wide X 14 ft. high trailer that can be moved over any highway requiring only a easily obtainable overweight permit because it weighs approximately 38 tons. It was built to conform to industry standards for a cabinet system which does not require an exclusion zone. The fact that this unit is mobile has allowed us to operate where the waste is stored, rather than having to move the waste to a fixed facility

  2. La creación de los Vales Reales = The creation of the Vales Reales

    Directory of Open Access Journals (Sweden)

    Pedro Damián Cano Borrego

    2016-06-01

    Full Text Available A finales del siglo XVIII la Monarquía adolecía de graves problemas económicos, derivados del estado permanente de guerra en el que se hallaba sumido el Reino, que impedía la arribada de remesas de metales preciosos y suponía unos ingentes gastos, lo que llevó a que a finales del reinado de Carlos III se creasen los Vales Reales, a modo de deuda pública. Por sus características, fueron desde el principio títulos de renta, amortizables en plazos más o menos grandes, dependiendo de las cláusulas que regían sus emisiones en un principio y más tarde de la situación del Tesoro Público. In the late eighteenth century the Spanish monarchy had serious economic problems arising from the permanent state of war in which they had sunk the Kingdom, which prevented the arrival of remittances of precious metals and assumed a heavy expenses, which led to the end the reign of Carlos III the creation of the Vales Reales, a kind of public debt. By their nature, they were from the beginning income securities, redeemable in larger or smaller periods, depending on the terms governing their emissions at first and later on the status of Treasury

  3. Referencias al contrabando en los informes de los «oidores» de la Real Audiencia de Extremadura

    Directory of Open Access Journals (Sweden)

    Eusebio MEDINA GARCÍA

    2009-11-01

    Full Text Available RESUMEN: En este artículo se recogen y se comentan las principales referencias sobre el contrabando tradicional en la frontera de España y Portugal, contenidas en los informes de los «oidores» (1791 y en otras disposiciones de la Real Audiencia de Extremadura. Además de resaltar la importancia que tuvo la instauración de la Real Audiencia de Extremadura en el proceso de consolidación de la Administración central en la región, ponemos de manifiesto el enorme interés de la autoridad real por conocer, para erradicar, los tráficos ilegales; siendo la recién estrenada —Real Audiencia—, un instrumento fundamental para implementar esa política de represión del contrabando en la frontera de Portugal, a finales del siglo XVIII.ABSTRACT: In this article the main references on the traditional smuggling in the border between Spain and Portugal, contained in the reports the «oidores» (1791 and in other regulations of the Royal Court of Extremadura are gathered and commented. Besides highlighting the great importance that the establishment of the Royal Court of Extremadura had in the process of consolidation of the state administration in the region, we point out the enormous interest of the Royal Authority in knowing the illegal trafficking to eradicate it. In this sense, the new Royal Court was a fundamental instrument to implement this policy of smuggling repression in the border at the end of 18th century.

  4. Caracterización de los nidos de Aguila Real (Aquila chrysaëtos) en Navarra.

    OpenAIRE

    FERNANDEZ, C., LEOZ, J.

    1986-01-01

    Se presentan los datos referentes a 90 nidos de 25 parejas de   Aguila real (A. chrysaëtus) establecidos en el extremo occidental   de la vertiente meridional de los Pirineos. Se obtienen conclusiones sobre: número de nidos utilizables por   pareja, distancias entre nidos, altitud y posición relativa de   los nidos en los cortados, localización de los nidos en los   árboles y cortados, orientaciones predominantes, construcción y   arreglo de los nidos, dimensiones de los ...

  5. Los Alamos low-level waste performance assessment status

    International Nuclear Information System (INIS)

    Wenzel, W.J.; Purtymun, W.D.; Dewart, J.M.; Rodgers, J.E.

    1986-06-01

    This report reviews the documented Los Alamos studies done to assess the containment of buried hazardous wastes. Five sections logically present the environmental studies, operational source terms, transport pathways, environmental dosimetry, and computer model development and use. This review gives a general picture of the Los Alamos solid waste disposal and liquid effluent sites and is intended for technical readers with waste management and environmental science backgrounds but without a detailed familiarization with Los Alamos. The review begins with a wide perspective on environmental studies at Los Alamos. Hydrology, geology, and meteorology are described for the site and region. The ongoing Laboratory-wide environmental surveillance and waste management environmental studies are presented. The next section describes the waste disposal sites and summarizes the current source terms for these sites. Hazardous chemical wastes and liquid effluents are also addressed by describing the sites and canyons that are impacted. The review then focuses on the transport pathways addressed mainly in reports by Healy and Formerly Utilized Sites Remedial Action Program. Once the source terms and potential transport pathways are described, the dose assessment methods are addressed. Three major studies, the waste alternatives, Hansen and Rogers, and the Pantex Environmental Impact Statement, contributed to the current Los Alamos dose assessment methodology. Finally, the current Los Alamos groundwater, surface water, and environmental assessment models for these mesa top and canyon sites are described

  6. Tiger Team Assessment of the Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    1991-11-01

    This report documents the Tiger Team Assessment of the Los Alamos National Laboratory (LANL) located in Los Alamos, New Mexico. LANL is operated for the US Department of Energy (DOE) by the University of California. The Tiger Team Assessment was conducted from September 23 to November 8, 1991, under the auspices of the DOE Office of Special Projects, Office of Assistant Secretary for Environment, Safety and Health. The assessment was comprehensive, encompassing environmental, safety, and health (ES ampersand H) disciplines; management; and contractor and DOE self-assessments. Compliance with applicable Federal, state, and local regulations; applicable DOE Orders; best management practices; and internal LANL site requirements was assessed. In addition, an evaluation of the adequacy and effectiveness of the DOE and the site contractors' management of ES ampersand H/quality assurance programs was conducted. This volume discusses findings concerning the environmental assessment

  7. Performance Characterization of a Real-Time Massive MIMO System with LOS Mobile Channels

    OpenAIRE

    Harris, Paul; Malkowsky, Steffen; Vieira, Joao; Hassan, Fredrik Tufvesson Wael Boukley; Liu, Liang; Beach, Mark; Armour, Simon; Edfors, Ove

    2017-01-01

    The first measured results for massive multiple input, multiple-output (MIMO) performance in a line-of-sight (LOS) scenario with moderate mobility are presented, with 8 users served in real-time using a 100 antenna base Station (BS) at 3.7 GHz. When such a large number of channels dynamically change, the inherent propagation and processing delay has a critical relationship with the rate of change, as the use of outdated channel information can result in severe detection and precoding inaccura...

  8. Efecto de la jalea real sobre la proliferación de los linfocitos humanos

    OpenAIRE

    del Valle Pérez, Lázaro O; Macías Abraham, Consuelo; Esquivel Suárez, Ileana; Rodríguez Amado, Jacqueline; Alpízar Olivares, Yulién; Torres Leyva, Isabel

    2001-01-01

    Se estudió el efecto in vitro de la jalea real (JR) sobre los linfocitos de 10 donantes voluntarios del Banco de Sangre del Instituto de Hematología e Inmunología mediante la prueba de transformación linfoblástica con el empleo de timidina tritiada. Se cultivaron 100 mL de la muestra (2 ´ 106 linf/mL) en las siguientes condiciones experimentales: 100 mL de RPMI 1640 suplementado con suero fetal bovino al 20 %, diluciones dobles de la JR (tableta 100 mg) desde 1:2 hasta 1:4096 respectivamente....

  9. Real-time alpha monitoring of a radioactive liquid waste stream at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Johnson, J.D.; Whitley, C.R.; Rawool-Sullivan, M. [Los Alamos National Lab., NM (United States)

    1995-12-31

    This poster display concerns the development, installation, and testing of a real-time radioactive liquid waste monitor at Los Alamos National Laboratory (LANL). The detector system was designed for the LANL Radioactive Liquid Waste Treatment Facility so that influent to the plant could be monitored in real time. By knowing the activity of the influent, plant operators can better monitor treatment, better segregate waste (potentially), and monitor the regulatory compliance of users of the LANL Radioactive Liquid Waste Collection System. The detector system uses long-range alpha detection technology, which is a nonintrusive method of characterization that determines alpha activity on the liquid surface by measuring the ionization of ambient air. Extensive testing has been performed to ensure long-term use with a minimal amount of maintenance. The final design was a simple cost-effective alpha monitor that could be modified for monitoring influent waste streams at various points in the LANL Radioactive Liquid Waste Collection System.

  10. Enfermedad pulmonar obstructiva crónica: los pacientes en la vida real. Estudio LEONPOC

    Directory of Open Access Journals (Sweden)

    Silvia García García

    2017-12-01

    Full Text Available Resumen: Objetivo: El objetivo de este estudio ha sido conocer las características de los pacientes EPOC por fenotipos y según la GOLD 2011-ABCD y el grado de concordancia de los tratamientos farmacológicos. Diseño: Estudio transversal de observación y descriptivo. Emplazamiento: Pacientes EPOC entre 40 y 85 años pertenecientes al Área de León que figuran en la base de datos MEDORA de Atención Primaria. Participantes: De los 5.522 pacientes recogidos en la base de datos de MEDORA con los criterios de selección descritos, se calculó un tamaño muestral de 734 sujetos, de los cuales se estudiaron finalmente 577 enfermos. Mediciones principales: Se diseñó un cuestionario estructurado para recoger la información sociodemográfica, clínica, tratamientos y calidad de vida. Se incluía realización de espirometría y prueba broncodilatadora. Resultados: De los 734 enfermos muestreados se ha conseguido estudiar al 78,6% (577. En 166 pacientes (28,7%, el diagnóstico había sido realizado exclusivamente por la clínica, sin constancia de espirometría en el MEDORA. En 123 (21,3% el índice FEV1/FVC fue superior a 0,7, por lo que se descartó el diagnóstico de EPOC. Con respecto a los tratamientos prescritos según fenotipos, observamos que en el fenotipo no agudizador existe una sobreprescripción de corticoides inhalados. Lo mismo sucede en los grupos A y B. Conclusiones: A pesar de las guías clínicas, el manejo de los pacientes con EPOC en la vida real sigue siendo mejorable, tanto en el aspecto diagnóstico como de medidas terapéuticas. Abstract: Objective: The purpose of this study was to evaluate different characteristics of COPD patients according to phenotypes and GOLD guidelines.according to GesEPOC phenotypes and GOLD 2011 ABCD guidelines and pharmacological treatment agreement. Design: Cross-sectional survey. Location: COPD patients aged 40-85 from Le

  11. ANALISIS ESTADISTICO IMPLICATIVO DE LOS CONOCIMIENTOS PREVIOS SOBRE NUMEROS REALES DE INGRESANTES A LA UNIVERSIDAD

    Directory of Open Access Journals (Sweden)

    Liliana Noemí Caputo

    2017-05-01

    Full Text Available DOI: 10.12957/cadest.2016.25323 El objetivo de este trabajo es presentar la técnica de análisis estadístico implicativo (ASI y ejemplificar su uso mediante el análisis de un ítem de la prueba de diagnóstico tomada en 2013 a ingresantes a la Facultad de Ciencias Exactas y Naturales y Agrimensura de la Universidad Nacional del Nordeste (Argentina. Como resultado del análisis se obtuvieron algunas relaciones establecidas por los sujetos evaluados  entre el conocimiento de ciertos números reales como elementos de - o de alguno de sus subconjuntos ( - y la representación correcta en la recta real de cuatro de ellos. La ausencia de algunas relaciones conceptuales esperadas (como por ejemplo entre el conocimiento del conjunto numérico al que pertenece un determinado número y su representación en la recta numérica permite detectar aquellas relaciones conceptuales que no integran la red cognitiva de los sujetos evaluados, lo cual parece estar indicando la necesidad de prever y poner en práctica actividades de enseñanza que favorezcan  el establecimiento de dichas relaciones.

  12. Emplazamiento hacia el ENE del manto de Los Reales (Alpujarrides occidentales: criterios estructurales y de petrofábrica

    Directory of Open Access Journals (Sweden)

    Tubía, J. M.

    1984-08-01

    Full Text Available Los Reales nappe rests over Ojén nappe to the North of Sierra Alpujata. The nappe contact zone shows a intense plastic deformation with mylonitic rocks, The deformation decreases progressively going away from the contacto The structural study of footwall and hangingwall roen permits to attribute this deformation to the Los Reales nappe emplacement over that of Ojén. The foliation and stretching lineation distributions show a WSW-ENE shear direction. The mylonite microstructural characteristics and the enstatite crystalline preferred orientations in the basal peridotites give a mear sense in according that, Los Reales nappe is displaced, in their present position, from the WSW towards the ENE.

    El manto de Los Reales descansa sobre el manto de Ojén, al norte de Sierra Alpujata. La zona de contacto entre mantos exhibe una intensa deformación plástica con rocas miloníticas; la deformación disminuye progresivamente al alejarse del contacto. El estudio estructural de las rocas infra y suprayacentes al contacto permite atribuir esta deformación al emplazamiento del manto de Los Reales sobre el de Ojén. , Las distribuciones de la foliación y de la lineación, de estiramiento indican una dirección de cizallamiento WSW-ENE. Las características microestructurales de las milonitas y las orientaciones preferentes cristalinas de la enstatita en las peridotitas basales proporcionan un sentido de cizallamiento tal que el manto de Los Reales se ha desplazado, en su posición actual, desde el WSW hacia el ENE.

  13. Getting Real: Implementing Assessment Alternatives in Mathematics.

    Science.gov (United States)

    Hopkins, Martha H.

    1997-01-01

    Recounts experiences of a university professor who returned to the elementary classroom and attempted to implement the National Council of Teachers of Mathematics Standards and appropriate assessment methods, including nontraditional paper-and-pencil tasks, journal-like writing assignments, focused observations, and performance-based assessments…

  14. Tiger Team Assessment of the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-01

    The purpose of the safety and health assessment was to determine the effectiveness of representative safety and health programs at the Los Alamos National Laboratory (LANL). Within the safety and health programs at LANL, performance was assessed in the following technical areas: Organization and Administration, Quality Verification, Operations, Maintenance, Training and Certification, Auxiliary Systems, Emergency Preparedness, Technical Support, Packaging and Transportation, Nuclear Criticality Safety, Security/Safety Interface, Experimental Activities, Site/Facility Safety Review, Radiological Protection, Personnel Protection, Worker Safety and Health (OSHA) Compliance, Fire Protection, Aviation Safety, Explosives Safety, Natural Phenomena, and Medical Services.

  15. Tiger Team Assessment of the Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    1991-11-01

    The purpose of the safety and health assessment was to determine the effectiveness of representative safety and health programs at the Los Alamos National Laboratory (LANL). Within the safety and health programs at LANL, performance was assessed in the following technical areas: Organization and Administration, Quality Verification, Operations, Maintenance, Training and Certification, Auxiliary Systems, Emergency Preparedness, Technical Support, Packaging and Transportation, Nuclear Criticality Safety, Security/Safety Interface, Experimental Activities, Site/Facility Safety Review, Radiological Protection, Personnel Protection, Worker Safety and Health (OSHA) Compliance, Fire Protection, Aviation Safety, Explosives Safety, Natural Phenomena, and Medical Services

  16. Real time source term and dose assessment

    International Nuclear Information System (INIS)

    Breznik, B.; Kovac, A.; Mlakar, P.

    2001-01-01

    The Dose Projection Programme is a tool for decision making in case of nuclear emergency. The essential input data for quick emergency evaluation in the case of hypothetical pressurised water reactor accident are following: source term, core damage assessment, fission product radioactivity, release source term and critical exposure pathways for an early phase of the release. A reduced number of radio-nuclides and simplified calculations can be used in dose calculation algorithm. Simple expert system personal computer programme has been developed for the Krsko Nuclear Power Plant for dose projection within the radius of few kilometers from the pressurised water reactor in early phase of an accident. The input data are instantaneous data of core activity, core damage indicators, release fractions, reduction factor of the release pathways, spray operation, release timing, and dispersion coefficient. Main dose projection steps are: accurate in-core radioactivity determination using reactor power input; core damage and in-containment source term assessment based on quick indications of instrumentation or on activity analysis data; user defines release pathway for typical PWR accident scenarius; dose calculation is performed only for exposure pathway critical for decision about evacuation or sheltering in early phase of an accident.(author)

  17. Tiger Team Assessment of the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    1991-11-01

    The Management Subteam conducted a management and organization assessment of environment, safety, and health (ES H) activities performed by the Los Alamos National Laboratory (LANL) and onsite contractor personnel. The objectives of the assessment were to (1) evaluate the effectiveness of management systems and practices in terms of ensuring environmental compliance and the safety and health of workers and the general public, (2) identify key findings, and (3) identify root causes for all ES H findings and concerns. The scope of the assessment included examinations of the following from an ES H perspective: (1) strategic and program planning; (2) organizational structure and management configuration; (3) human resource management, including training and staffing; (4) management systems, including performance monitoring and assessment; (5) conduct of operations; (6) public and institutional interactions; and (7) corporate'' parent support.

  18. Mejora de los Test de Planificabilidad para Asignación Incremental de Tareas en Sistemas Multiprocesadores de Tiempo Real

    Directory of Open Access Journals (Sweden)

    Sergio Sáez

    2013-04-01

    Full Text Available Resumen: Durante la etapa de diseño de un sistema multiprocesador de tiempo real, los test de planificabilidad son una parte clave de los algoritmos de asignación de tareas. El uso de test de planificabilidad exactos permite aumentar la eficiencia de los algoritmos de asignación a costa de un incremento en el tiempo de computo necesario para validar una partición. Aunque existen varios estudios que mejoran el rendimiento de dichos test de planificabilidad, ninguno se ha centrado en el contexto en que dichos test se utilizan. Este trabajo presenta diversas mejoras en los test de planificabilidad exactos basándose en la naturaleza incremental del proceso de asignación. Abstract: During the design of a Real-Time Multiprocessor System, schedulability tests are a key component of the task allocation algorithms. Using exact schedulability tests increases the efficiency of these allocation algorithms, but the execution cost to validate a task partition is also greatly increased. Although several improvement to these schedulability test have been recently published, their use in the multiprocessor context is still unaddressed. This work presents several improvements to execution costs of the schedulability test when they are used by task allocation algorithms taking advantage of the incremental nature of this allocation process. Palabras clave: Sistema Multiprocesadores, Análisis de Planificabilidad, Sistema de Tiempo Real, Keywords: Multiprocessor Systems, Schedulability Analysis, Real-Time Systems

  19. Efectos de los emplazamientos de marca real y enmascarada en el comportamiento del consumidor: un experimento exploratorio

    Directory of Open Access Journals (Sweden)

    Alejandro Alvarado Herrera

    2014-10-01

    Full Text Available La efectividad del emplazamiento de marcas enmascaradas en el comportamiento del consumidor no ha sido comparada empíricamente con la producida por el emplazamiento de marcas reales. Para hacerlo, se realizó un experimento exploratorio verdadero (post-test en 4 ciudades mexicanas. Una animación de HuevoCartoon con 3 versiones desarrolladas ex profeso, manipulando la variable Tipo de emplazamiento, fue presentada a 183 participantes voluntarios repartidos aleatoriamente en los grupos y, posteriormente, se solicitó que respondieran un cuestionario que midió 7 variables dependientes referentes a los efectos cognitivos, emocionales y conativos producidos en los sujetos. Los resultados permiten concluir que la diferencia en la efectividad del uso de ambos tipos de emplazamiento es meramente marginal.

  20. Los Alamos National Laboratory 1995 self assessment report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-06-30

    The Los Alamos National Laboratory (LANL) Safeguards and Security (S and S) Assurance Program (AP) is designed to ensure the adequacy and effectiveness of the LANL S and S program. The Assurance Program provides a mechanism for discovering deficiencies, determining causes, conducting risk assessments, implementing corrective actions, and documenting the assessment process. Selection of organizations for self assessments is based on the criteria established in the LANL S and S Assurance Program. For FY 1995, 12 organizations were selected for self assessments, these organizations are identified fin the schedule at Appendix A. The S and S topical areas selected for review in each organization varied depending on their security interests and included: Program Planning and Management (PPM); Protection Program Operations (PPO); Material Control and Accountability (MC and A); Computer and Communications Security (COMPSEC and COMSEC); Information Security (INFOSEC); Personnel Security (PERSEC); and Operational Security (OPSEC). The objective was to ascertain the effectiveness of S and S programs in each organization, its formality of operations, and its integration with the overall Laboratory S and S program. The goal was to meet both the DOE self-assessment requirements and the UC performance criteria and document the results.

  1. Los Alamos National Laboratory 1995 self assessment report

    International Nuclear Information System (INIS)

    1995-01-01

    The Los Alamos National Laboratory (LANL) Safeguards and Security (S and S) Assurance Program (AP) is designed to ensure the adequacy and effectiveness of the LANL S and S program. The Assurance Program provides a mechanism for discovering deficiencies, determining causes, conducting risk assessments, implementing corrective actions, and documenting the assessment process. Selection of organizations for self assessments is based on the criteria established in the LANL S and S Assurance Program. For FY 1995, 12 organizations were selected for self assessments, these organizations are identified fin the schedule at Appendix A. The S and S topical areas selected for review in each organization varied depending on their security interests and included: Program Planning and Management (PPM); Protection Program Operations (PPO); Material Control and Accountability (MC and A); Computer and Communications Security (COMPSEC and COMSEC); Information Security (INFOSEC); Personnel Security (PERSEC); and Operational Security (OPSEC). The objective was to ascertain the effectiveness of S and S programs in each organization, its formality of operations, and its integration with the overall Laboratory S and S program. The goal was to meet both the DOE self-assessment requirements and the UC performance criteria and document the results

  2. Domingo del Monte, ¿“El más real y útil de los cubanos de su tiempo”?

    Directory of Open Access Journals (Sweden)

    Francisco Morán

    2016-07-01

    Full Text Available José Martí llamó a Domingo del Monte “el más real y útil de los cubanos de su tiempo”. Los estudiosos de la cultura cubana no han dejado de usar la frase para afirmar el protagonismo de Del Monte en la gestación de la conciencia nacional. Al discutir principalmente la correspondencia de Del Monte con el diplomático norteamericano Alexander Everett, este artículo demuestra que, paradójicamente, el juicio martiano inscribió una cubanidad enlazada al racismo y al anexionismo.

  3. Real-time Color Codes for Assessing Learning Process

    OpenAIRE

    Dzelzkalēja, L; Kapenieks, J

    2016-01-01

    Effective assessment is an important way for improving the learning process. There are existing guidelines for assessing the learning process, but they lack holistic digital knowledge society considerations. In this paper the authors propose a method for real-time evaluation of students’ learning process and, consequently, for quality evaluation of teaching materials both in the classroom and in the distance learning environment. The main idea of the proposed Color code method (CCM) is to use...

  4. Real Time Face Quality Assessment for Face Log Generation

    DEFF Research Database (Denmark)

    Kamal, Nasrollahi; Moeslund, Thomas B.

    2009-01-01

    Summarizing a long surveillance video to just a few best quality face images of each subject, a face-log, is of great importance in surveillance systems. Face quality assessment is the back-bone for face log generation and improving the quality assessment makes the face logs more reliable....... Developing a real time face quality assessment system using the most important facial features and employing it for face logs generation are the concerns of this paper. Extensive tests using four databases are carried out to validate the usability of the system....

  5. A real-time internal dose assessment exercise

    International Nuclear Information System (INIS)

    Bingham, D.; Bull, R. K.

    2013-01-01

    A real-time internal dose assessment exercise has been conducted in which participants were required to make decisions about sampling requirements, seek relevant information about the 'incident' and make various interim dose assessments. At the end of the exercise, each participant was requested to make a formal assessment, providing statements of the methods, models and assumptions used in that assessment. In this paper we describe how the hypothetical assessment case was set up and the exercise was conducted, the responses of the participants and the assessments of dose that they made. Finally we discuss the lessons learnt from the exercise and suggest how the exercise may be adapted to a wider range of participants. (authors)

  6. Aplicación de las opciones reales en la toma de decisiones en los mercados de electricidad

    Directory of Open Access Journals (Sweden)

    Felipe Isaza Cuervo

    2014-01-01

    Full Text Available Las decisiones estratégicas en los mercados de electricidad están sujetas a un alto riesgo e incertidumbre; en consecuencia, las opciones reales aparecen como una alternativa para la toma de decisiones en dichos mercados. En el presente artículo se realiza una revisión de literatura analizando y clasificando aplicacio- nes de opciones reales sobre decisiones de inversión, operación, y de políticas y programas energéticos. Además se presenta un ejemplo sintético de aplicación teórico utilizando un modelo binomial para incor- porar energía eólica en vez de térmica de acuerdo con la volatilidad de los precios del carbón. Se concluye que las opciones reales permiten tomar mejores decisiones que los métodos tradicionales, pues capturan a través de sus múltiples modelos las diferentes incertidumbres propias de estos mercados.

  7. Aplicación de las opciones reales en la toma de decisiones en los mercados de electricidad

    Directory of Open Access Journals (Sweden)

    Felipe Isaza Cuervo

    2014-10-01

    Full Text Available Las decisiones estratégicas en los mercados de electricidad están sujetas a un alto riesgo e incertidumbre; en consecuencia, las opciones reales aparecen como una alternativa para la toma de decisiones en dichos mercados. En el presente artículo se realiza una revisión de literatura analizando y clasificando aplicaciones de opciones reales sobre decisiones de inversión, operación, y de políticas y programas energéticos. Además se presenta un ejemplo sintético de aplicación teórico utilizando un modelo binomial para incorporar energía eólica en vez de térmica de acuerdo con la volatilidad de los precios del carbón. Se concluye que las opciones reales permiten tomar mejores decisiones que los métodos tradicionales, pues capturan a través de sus múltiples modelos las diferentes incertidumbres propias de estos mercados.

  8. Million trees Los Angeles canopy cover and benefit assessment

    Science.gov (United States)

    E.G. McPherson; J.R. Simpson; Q. Xiao; C. Wu

    2011-01-01

    The Million Trees LA initiative intends to improve Los Angeles’s environment through planting and stewardship of 1 million trees. The purpose of this study was to measure Los Angeles’s existing tree canopy cover (TCC), determine if space exists for 1 million additional trees, and estimate future benefits from the planting. High-resolution QuickBird remote sensing data...

  9. Assessing urban forest effects and values, Los Angeles' urban forest

    Science.gov (United States)

    David J. Nowak; Robert E. III Hoehn; Daniel E. Crane; Lorraine Weller; Antonio. Davila

    2011-01-01

    An analysis of trees in Los Angeles, CA, reveals that this area has about 6 million trees with tree and shrub canopies that cover 24.9 percent of the city. The most common tree species are Italian cypress, scrub oak, laurel sumac, Mexican fan palm, and Indian laurel, Trees in Los Angeles currently store about 1.3 million tons of carbon (4.7 million tons CO2...

  10. Needs assessment for fire department services and resources for the Los Alamos National Laboratory, Los Alamos, New Mexico. Final report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-11-15

    This report has been developed in response to a request from the Los Alamos National Laboratory (LANL) to evaluate the need for fire department services so as to enable the Laboratory to plan effective fire protection and thereby: meet LANL`s regulatory and contractual obligations; interface with the Department of Energy (DOE) and other agencies on matters relating to fire and emergency services; and ensure appropriate protection of the community and environment. This study is an outgrowth of the 1993 Fire Department Needs Assessment (prepared for DOE) but is developed from the LANL perspective. Input has been received from cognizant and responsible representatives at LANL, DOE, Los Alamos County (LAC) and the Los Alamos Fire Department (LAFD).

  11. Real-time risk assessment of operational events

    International Nuclear Information System (INIS)

    Perryman, L.J.; Foster, N.A.S.; Nicholls, D.R.; Grobbelaar, J.F.

    1996-01-01

    Probabilistic risk assessment (PRA) has always been fundamental to the licensing process of Koeberg nuclear power station. Furthermore, over the past 8 years PRA has assisted in many areas of operation. One of these areas is the real-time assessment of abnormal operating events. Over the years, considerable experience has been gained in using PRA to improve plant safety and performance. This paper presents some of the insights obtained in using PRA in such a dynamic role and demonstrates that, by developing and using the plant-specific 'living' PRA, considerable safety and financial gains can be obtained. These insights specifically concern the prerequisites before optimal use of a plant-specific 'living' PRA can be made. Finally, examples are presented of occurrences when PRA was used to improve plant safety and performance. These examples serve to demonstrate the advantages that can be obtained if sufficient resources are placed at the disposal of the PRA team. (orig.)

  12. Development of a real-time radiological dose assessment system

    Energy Technology Data Exchange (ETDEWEB)

    Han, Moon Hee; Lee, Young Bok; Kim, Eun Han; Suh, Kyung Suk; Hwang, Won Tae; Choi, Young Gil

    1997-07-01

    A radiological dose assessment system named FADAS has been developed. This system is necessary to estimated the radiological consequences against a nuclear accident. Mass-consistent wind field module was adopted for the generation of wind field over the whole domain using the several measured wind data. Random-walk dispersion module is used for the calculation of the distribution of radionuclides in the atmosphere. And volume-equivalent numerical integration method has been developed for the assessment of external gamma exposure given from a randomly distributed radioactive materials and a dose data library has been made for rapid calculation. Field tracer experiments have been carried out for the purpose of analyzing the site-specific meteorological characteristics and increasing the accuracy of wind field generation and atmospheric dispersion module of FADAS. At first, field tracer experiment was carried out over flat terrain covered with rice fields using the gas samplers which were designed and manufactured by the staffs of KAERI. The sampled gas was analyzed using gas chromatograph. SODAR and airsonde were used to measure the upper wind. Korean emergency preparedness system CARE was integrated at Kori 4 nuclear power plants in 1995. One of the main functions of CARE is to estimate the radiological dose. The developed real-time dose assessment system FADAS was adopted in CARE as a tool for the radiological dose assessment. (author). 79 refs., 52 tabs., 94 figs.

  13. Animales notables: la percepción de los brasileños sobre la fauna en el billete del Real

    Directory of Open Access Journals (Sweden)

    Graziele Scalfi

    2016-01-01

    Full Text Available Brasil es considerada una nación mega diversa, poseedora de algunos de los grupos de especies animales más numerosos del mundo. El billete del Real, la moneda brasileña, homenajea esta rica fauna desde 1994. Cerca de 190 millones de billetes circulan todos los días en las manos de los brasileños, pero ¿será que esa enorme exposición es suficiente para que la población reconozca esa fauna? Este artículo, evalúa la percepción de los brasileños con relación a la divulgación de los animales de la fauna brasileña en los billetes del Real. El análisis, se basa en las actividades realizadas durante la 10org.siir.client.entities.Sup@3ccd9945 Semana Nacional de Ciencia y Tecnología, en octubre de 2013, en el campus de la Universidad Estatal de Campinas (Unicamp y en el Parque Taquaral, en Campinas, en el estado de San Pablo. Los participantes fueron invitados a escoger especies que ilustraban cada uno de los seis billetes del Real y responder un cuestionario relativo a los hábitos de los animales brasileños retratados. Participaron en dicha actividad 159 personas, 86 de ellas individualmente y 73 en pareja o en grupo. Aunque los billetes son parte de su día a día, los participantes recordaban vagamente a los animales impresos en los billetes, aun mostrando 16 imágenes de animales, seis de los cuales, aparecen impresos en los billetes. El resultado indica que la divulgación científica tiene un gran reto por delante, una vez que la información habitual como lo es la fauna en el Real, no es suficiente para que la población identifique las especies nativas de Brasil.

  14. Beneficios que aporta la metodología MDE a los entornos de desarrollo de sistemas de tiempo real

    Directory of Open Access Journals (Sweden)

    César Cuevas

    2013-04-01

    Full Text Available Resumen: Se analizan los beneficios que aporta el empleo de la metodología Model-Driven Engineering (MDE cuando se utiliza como base y soporte de entornos de diseño de sistemas de tiempo real. Con esta metodología, se incrementa la facilidad de uso del entorno para el diseñador, ya que, en función del paradigma que utilice y de la fase del proceso de diseño que esté llevando a cabo, el entorno le ofrece una vista especializada del sistema, la cual presenta de una forma precisa y coherente la información sobre la que está decidiendo. Por otro lado, una infraestructura MDE facilita el desarrollo de herramientas y su integración en el entorno, ya que, a través de los mecanismos de gestión y transformación de modelos con los que está dotada, cada herramienta recibe únicamente la información que utiliza, estructurada de modo adecuado, y así mismo, puede generar sus resultados de la forma que le sea natural, ya que el entorno los sabe gestionar. Por último, la metodología MDE permite considerar el entorno de diseño de tiempo real como una vista especializada que se integra coherentemente en un entorno más general, el cual soporta las restantes fases del diseño del sistema. Abstract: This paper analyses the benefits provided by the Model-Driven Engineering (MDE methodology when it is used as the base support for real-time systems design environments. The application of MDE eases the environment usage by the designer, because depending on the chosen paradigm and on the stage of the development process, the environment offers a specialized view of the system, presenting in a precise and coherent fashion the information under decision. On the other hand, an MDE infrastructure facilitates the development of tools and their integration within the environment, as, through the model management and transformation mechanisms this infrastructure is equipped with, every tool receives as input the right information it uses, structured as it

  15. Los Angeles 1-Million tree canopy cover assessment

    Science.gov (United States)

    Gregory E. McPherson; James R. Simpson; Qingfu Xiao; Wu Chunxia

    2008-01-01

    The Million Trees LA initiative intends to chart a course for sustainable growth through planting and stewardship of trees. The purpose of this study was to measure Los Angeles's existing tree canopy cover (TCC), determine if space exists for 1 million additional trees, and estimate future benefits from the planting. High resolution QuickBird remote sensing data,...

  16. Real Time Assessment of Young Adults' Attitudes toward Tobacco Messages.

    Science.gov (United States)

    Hébert, Emily T; Vandewater, Elizabeth A; Businelle, Michael S; Harrell, Melissa B; Kelder, Steven H; Perry, Cheryl L

    2018-01-01

    We used ecological momentary assessment (EMA) to examine young adults' attitudes towards pro-tobacco messages encountered in real time and their association with intentions to use tobacco. Young adults (N = 92, ages 18-29) recorded sightings of marketing or social media related to tobacco in real time via mobile app for 28 days. Participants reported message characteristics, their attitudes towards the message, and intentions to use the depicted product for each submission. We used generalized linear mixed models to examine factors related to attitude towards message and intentions to use tobacco. Messages depicting e-cigarettes (p < .001) or hookah (p < .05) were associated with significantly more favorable attitudes compared with traditional cigarettes. Positive attitude towards the message was significantly associated with intention to use the depicted product (p < .001). Messages depicting e-cigarettes and hookah were significantly associated with higher intention to use. Message source was not significantly related to attitudes towards the message or product use intentions. Marketing featuring e-cigarettes and hookah is an important target for future regulation. Given that pro-tobacco and e-cigarette messages are prevalent online, future research should consider the Internet and social media as important venues for counter-marketing and intervention efforts.

  17. Estados, clases y Real Hacienda en los inicios de la conquista del Perú

    Directory of Open Access Journals (Sweden)

    Acosta, Antonio

    2006-04-01

    Full Text Available The article focuses the existence of economic and social contradictions among the various groups of interests within the society and the bureaucracy of the Monarchy at the beginning of the XVIth century. They projected themselves to the conquest of the Indies and their effects, contradictory too, are the central problem of the study.

    El artículo aborda la existencia de una serie de contradicciones económicas y sociales entre los diferentes grupos de intereses existentes en la sociedad y en la administración de la Monarquía castellana al comienzo del siglo XVI. Dichas contradicciones se proyectaron en la conquista de las Indias y sus efectos, igualmente de carácter contrapuesto, constituyen el problema central del trabajo.

  18. LOS Throughput Measurements in Real-Time with a 128-Antenna Massive MIMO Testbed

    OpenAIRE

    Harris, Paul; Zhang, Siming; Beach, Mark; Mellios, Evangelos; Nix, Andrew; Armour, Simon; Doufexi, Angela; Nieman, Karl; Kundargi, Nikhil

    2017-01-01

    This paper presents initial results for a novel 128-antenna massive Multiple-Input, Multiple- Output (MIMO) testbed developed through Bristol Is Open in collaboration with National Instruments and Lund University. We believe that the results presented here validate the adoption of massive MIMO as a key enabling technology for 5G and pave the way for further pragmatic research by the massive MIMO community. The testbed operates in real-time with a Long-Term Evolution (LTE)-like PHY in Time Div...

  19. Arte y arquitectura efímera en los funerales reales de Córdoba del Tucumán

    Directory of Open Access Journals (Sweden)

    Page, Carlos A.

    2009-12-01

    Full Text Available The subject on you honors them and exequies real has had in the last decades a particular consideration, mainly for the accomplishments conducted in the great Hispano-American capitals. But these manifestations also appear in other cities, like Cordoba del Tucumán, where the Jesuits established the first university in Argentina. From his foundation (1573 it depended soon on the virreinato of the Perú and of the Río de la Plata when was designated to head of the government (1785. In happening of two centuries of history it was witness of a series of real mournful celebrations of which they have been left little testimonies documentary and that we try to rescue in this article. The excellent graphical representations of tumuli have not been conserved of Cordoba as those of Lima or Mexico, but several documents that describe these monuments that were the best exponent of the ephemeral architecture of their time. They are testimonies that made meet systems of representation which they allowed to expose in addition to the architecture, the sculpture, painting and literature that located as opposed to the spectator all the artistic expressions that could transmit the painful message.El tema sobre las honras y exequias reales ha tenido en las últimas décadas una particular consideración, sobre todo para las realizaciones efectuadas en las grandes capitales hispanoamericanas. Pero estas manifestaciones también aparecen en otras ciudades, como Córdoba del Tucumán, donde los jesuitas establecieron la primera universidad argentina. Desde su fundación (1573 dependió del virreinato del Perú y luego del Río de la Plata cuando fue designada cabecera de la gobernación homónima (1785. En el devenir de dos siglos de historia fue testigo de una serie de celebraciones luctuosas reales de las que han quedado escasos testimonios documentales y que pretendemos rescatar en este artículo. No se han conservado de Córdoba las excelentes representaciones

  20. LIBERACIÓN EN TIEMPO REAL DE LOS PRODUCTOS COMERCIALES DEL CENTRO DE INMUNOLOGÍA MOLECULAR

    Directory of Open Access Journals (Sweden)

    Antonio E. Vallín García

    2010-11-01

    Full Text Available

    Este artículo describe un Procedimiento de Liberación en Tiempo Real para los productos comerciales del Centro de Inmunología Molecular. El Procedimiento incorpora el conocimiento del proceso a través de todas las etapas del proceso productivo, evaluando los parámetros y controles de proceso para asegurar la calidad del Ingrediente Farmacéutico Activo y del Producto Final.  La aplicación sistemática disminuirá significativamente el tiempo de liberación, garantizando la calidad del producto, el cumplimiento de las regulaciones y mayor conocimiento del proceso y del producto.

     

    This article describes a Procedure of Liberation in Real Time for the commercial products of the Center of Molecular Immunology. The Procedure incorporates the knowledge of the process through all the stages of the productive process, evaluating the parameters and process controls to assure the quality of the Active Pharmaceutical Ingredient and of the Final Product.  The systematic application will diminish the time of liberation, significantly guaranteeing the quality of the product, the execution of the regulations and bigger knowledge of the process and of the product.

  1. Environmental assessment for effluent reduction, Los Alamos National Laboratory, Los Alamos, New Mexico

    International Nuclear Information System (INIS)

    1996-01-01

    The Department of Energy (DOE) proposes to eliminate industrial effluent from 27 outfalls at Los Alamos National Laboratory (LANL). The Proposed Action includes both simple and extensive plumbing modifications, which would result in the elimination of industrial effluent being released to the environment through 27 outfalls. The industrial effluent currently going to about half of the 27 outfalls under consideration would be rerouted to LANL's sanitary sewer system. Industrial effluent from other outfalls would be eliminated by replacing once-through cooling water systems with recirculation systems, or, in a few instances, operational changes would result in no generation of industrial effluent. After the industrial effluents have been discontinued, the affected outfalls would be removed from the NPDES Permit. The pipes from the source building or structure to the discharge point for the outfalls may be plugged, or excavated and removed. Other outfalls would remain intact and would continue to discharge stormwater. The No Action alternative, which would maintain the status quo for LANL's outfalls, was also analyzed. An alternative in which industrial effluent would be treated at the source facilities was considered but dismissed from further analysis because it would not reasonably meet the DOE's purpose for action, and its potential environmental effects were bounded by the analysis of the Proposed Action and the No Action alternatives

  2. Black Gold, White Power: Mapping Oil, Real Estate, and Racial Segregation in the Los Angeles Basin, 1900-1939

    Directory of Open Access Journals (Sweden)

    Daniel G. Cumming

    2018-03-01

    Full Text Available In 1923, Southern California produced over twenty percent of the world’s oil. At the epicenter of an oil boom from 1892 to the 1930s, Los Angeles grew into the nation’s fifth largest city. By the end of the rush, it had also become one of the most racially segregated cities in the country. Historians have overlooked the relationship between industrialists drilling for oil and real estate developers codifying a racist housing market, namely through “redlining” maps and mortgage lending. While redlining is typically understood as a problem of horizontal territory, this paper argues that the mapping of the underground—the location and volume of subterranean oil fields, in particular—was a crucial technique in underwriting urban apartheid. Mapping technologies linked oil exploitation with restrictive property rights, constructing oil as a resource and vertically engineering a racialized housing market. By focusing on petro-industrialization interlocked with segregationist housing, this article reveals an unexamined chapter in Los Angeles’s history of resource exploitation and racial capitalism. Moreover, it contributes to a growing literature on the social production of resources, extractive technology and political exclusion, and the technoscientific practices used by states and corporations to mine the underground while constructing metropolitan inequality above ground.

  3. Relevancia de los diferentes momentos del juego y de las acciones a balón parado (ABP en los rendimientos del FC Barcelona y Real Madrid durante la liga nacional de fútbol profesional 2011/12

    Directory of Open Access Journals (Sweden)

    Xavier Planes i Fontestad

    2015-08-01

    Full Text Available El estudio se centra en la relevancia de las fases dinámicas y estáticas en los rendimientos del FC Barcelona y Real Madrid. Utilizamos la metodología observacional con el fin de tratar de asociar los diferentes Momentos o Fases del juego (MJ y las Acciones a Balón Parado (ABP con la obtención de cada uno de los goles. Para conseguirlo, hemos creado un instrumento de observación ad hoc (IOX y hemos utilizado dos instrumentos de registro (LINCE y MOTS. Para el análisis de los datos del registro y la obtención de resultados, hemos utilizado las técnicas de comparación de proporciones con el software Statgraphics, habiendo encontrado, inicialmente, diferencias significativas entre los dos equipos únicamente en la fase defensiva.

  4. Relación de largo plazo y análisis de causalidad y sensibilidad entre los salarios reales y la productividad laboral en el sector manufacturero a partir de cifras de los departamentos en Colombia

    Directory of Open Access Journals (Sweden)

    John Alexander Méndez Sayago

    2015-06-01

    Full Text Available Este artículo se enfoca en identificar la relación entre los salarios y la productividad. Para comprobar si existe una relación de largo plazo entre estas variables, se realizan pruebas de raíz unitaria y cointegración para determinar si las series comparten tendencias estocásticas comunes. También se estimó un modelo de vectores autorregresivos (VAR para realizar un análisis de causalidad y sensibilidad, y así determinar cuál es el efecto futuro de los choques en cualquier variable del sistema, sobre ella misma y sobre la otra. Para el ejercicio empírico, se emplearon las series de productividad y salarios de 24 departamentos de Colombia, calculadas a partir de la información de la encuesta anual manufacturera. Los hallazgos empíricos permiten concluirque en Colombia existe un conflicto en la distribución de la riqueza porque los cambios en la productividad no se reflejan en incrementos de los salarios reales de los trabajadores. Por otra parte, a los empresarios no les conviene aumentar el salario real porque ese incremento no tiene un efecto futuro positivo sobre la productividad.

  5. A real-time assessment of factors influencing medication events.

    Science.gov (United States)

    Dollarhide, Adrian W; Rutledge, Thomas; Weinger, Matthew B; Fisher, Erin Stucky; Jain, Sonia; Wolfson, Tanya; Dresselhaus, Timothy R

    2014-01-01

    Reducing medical error is critical to improving the safety and quality of healthcare. Physician stress, fatigue, and excessive workload are performance-shaping factors (PSFs) that may influence medical events (actual administration errors and near misses), but direct relationships between these factors and patient safety have not been clearly defined. This study assessed the real-time influence of emotional stress, workload, and sleep deprivation on self-reported medication events by physicians in academic hospitals. During an 18-month study period, 185 physician participants working at four university-affiliated teaching hospitals reported medication events using a confidential reporting application on handheld computers. Emotional stress scores, perceived workload, patient case volume, clinical experience, total sleep, and demographic variables were also captured via the handheld computers. Medication event reports (n = 11) were then correlated with these demographic and PSFs. Medication events were associated with 36.1% higher perceived workload (p sleep (p = .10). These results confirm the effect of factors influencing medication events, and support attention to both provider and hospital environmental characteristics for improving patient safety. © 2013 National Association for Healthcare Quality.

  6. SNM holdup assessment of Los Alamos exhaust ducts

    International Nuclear Information System (INIS)

    Marshall, R.S.

    1994-02-01

    Fissile material holdup in glovebox and fume hood exhaust ducting has been quantified for all Los Alamos duct systems. Gamma-based, nondestructive measurements were used to quantify holdup. The measurements were performed during three measurement campaigns. The first campaign, Phase I, provided foot-by-foot, semiquantitative measurement data on all ducting. These data were used to identify ducting that required more accurate (quantitative) measurement. Of the 280 duct systems receiving Phase I measurements, 262 indicated less than 50 g of fissile holdup and 19 indicated fissile holdup of 50 or more grams. Seven duct systems were measured in a second campaign, called Series 1, Phase II. Holdup estimates on these ducts ranged from 421 g of 235 U in a duct servicing a shut-down uranium-machining facility to 39 g of 239 Pu in a duct servicing an active plutonium-processing facility. Measurements performed in the second campaign proved excessively laborious, so a third campaign was initiated that used more efficient instrumentation at some sacrifice in measurement quality. Holdup estimates for the 12 duct systems measured during this third campaign ranged from 70 g of 235 U in a duct servicing analytical laboratories to 1 g of 235 U and 1 g of 239 Pu in a duct carrying exhaust air to a remote filter building. These quantitative holdup estimates support the conclusion made at the completion of the Phase I measurements that only ducts servicing shut-down uranium operations contain about 400 g of fissile holdup. No ventilation ducts at Los Alamos contain sufficient fissile material holdup to present a criticality safety concern

  7. EFECTOS DE LOS CHOQUES DE ORIGEN EXTERNO SOBRE LA PRODUCCIÓN Y EL TIPO DE CAMBIO REAL DE COSTA RICA

    Directory of Open Access Journals (Sweden)

    José Mayorga V.

    2011-09-01

    Full Text Available Se aplicó la técnica de vectores autorregresivos (VAR a datos trimestrales del periodo 1982 a 1995, para analizar los principales efectos que generan sobre la producción y el tipo de cambio real de Costa Rica, los choques externos comerciales y financieros. Los primeros fueron aproximados por indicadores de demanda externa y de precios internacionales (PIB de EEUU y la relación de términos de intercambio del país; los segundos, por la tasa de interés estadounidense. Con respecto a otras investigaciones sobre el tema, el estudio permite tener idea sobre la magnitud, el sentido y la permanencia de los choques.La evidencia estadística sugiere que un aumento en el dinamismo de la economía mundial tiende a producir un aumento permanente y amplio en la producción nacional y una apreciación real reducida y transitoria del colón (de poco más de un año luego de ocurrido el evento.Un mejoramiento de los precios relativos de los bienes objeto de comercio internacional del país tiende a aumentar en forma limitada y por corto tiempo (medio año el PIB doméstico y a ocasionar una apreciación del colón reducida aunque de duración importante (alrededor de dos años y medio.Un aumento de las tasas de interés externas afecta negativamente el producto real del país y, sorprendentemente, aprecia en términos reales, en forma permanente y profunda, al colón.

  8. TRAC-PF1/MOD1 assessment at Los Alamos

    International Nuclear Information System (INIS)

    Knight, T.D.

    1984-01-01

    The Los Alamos National Laboratory is developing the Transient Reactor Analysis Code (TRAC) to provide an advanced best-estimate predictive capability for the analysis of postulated accidents in pressurized water reactors (PWRs). Over the past several years, four distinct versions of the code have been released; each new version introduced improvements to the existing models and numerics and added new models to extend the applications of the code. The first goal of the code was to analyze large-break loss-of-coolant accidents (LOCAs), and the TRAC-P1A and TRAC-PD2 codes primarily addressed the large-break LOCA. (The TRAC-PD2/MOD1 code is essentially the same as the TRAC-PD2 code but it also includes a released set of error corrections.) The TRAC-PF1 code contained major changes to the models and trips and to the numerical methods. These modifications enhanced the computational speed of the code and improved the application to small-break LOCAs. The TRAC-PF1/MOD1 code, the latest released version, added improved steam-generator modeling, a turbine component, and a control system together with modified constitutive relations to model the balance of plant on the secondary side and to extend the applications to non-LOCA transients. The TRAC-PF1/MOD1 code also contains reasonably general reactor-kinetics modeling to facilitate the simulation of transients with delayed scram or without scram. 13 references, 24 figures

  9. La hipótesis de los tres registros - simbólico, imaginario, real - en la enseñanza de J. Lacan The three registers hypothesis - symbolic, imaginary, real - in the J. Lacan work

    Directory of Open Access Journals (Sweden)

    Manuel Murillo

    2011-12-01

    Full Text Available En el presenta trabajo exploramos algunos interrogantes en torno a lo que llamamos la hipótesis de los tres registros -simbólico, imaginario, real- en la enseñanza de J. Lacan. El objetivo que nos propusimos fue identificar los momentos privilegiados en la enseñanza de Lacan para el abordaje en la temática y describir su hipótesis de los tres registros. De acuerdo a nuestra hipótesis los tres registros constituyen en la enseñanza de Lacan una tesis inédita en el campo del psicoanálisis que implica a la vez un retorno a Freud y una interrogación a Freud. Para este estudio nos hemos servido principalmente de la conferencia que Lacan dictó en 1953 sobre los tres registros, y del seminario 22 de 1974-1975, también dedicado, en gran medida, a los tres registros. Concluimos que los registros son los nombres del padre, a la par que las dimensiones del ser hablante y los fundamentos del discurso y práctica psicoanalíticos.In this paper we explore some questions about what we call the three registers hypothesis -symbolic, imaginary, real- in J. Lacan work. The objective we set was to identify the pivotal moments in the work of Lacan to approach the subject and describe his three records hypothesis. According to our hypothesis, three records are in the work of Lacan an original thesis in the psychoanalysis field, which involves both a return to Freud and an interrogation to Freud. For this study we used mainly the conference that Lacan gave in 1953 on three records, and the seminar 22, 1974-1975, also dedicated largely to the three records. We conclude that the records are the father's names, and at the same time, the speaking being dimensions and psychoanalytic discourse and practice fundaments.

  10. La comunicación digital del FC Barcelona y del Real Madrid CF y su percepción por los periodistas deportivos / Digital communication of FC Barcelona and Real Madrid CF and its perception by sports journalists

    Directory of Open Access Journals (Sweden)

    Fernando Olabe Sánchez

    2012-12-01

    Full Text Available ResumenEl FC Barcelona y el Real Madrid CF han cambiado su modelo de gestión comunicativa, especialmente en su relación con los medios de comunicación. Favorecidos por la implantación de las TIC, los departamentos de Comunicación de estas entidades se constituyen en gatekeeper al controlar y emitir, a través de sus propios medios de comunicación, como las televisiones y radios propias y los soportes online, las informaciones que ellos mismos generan. De este modo, controlan los mensajes y los emiten directamente a sus públicos objetivos sin la intermediación de los medios convencionales, condicionando las rutinas productivas de los periodistas deportivos.El objetivo de este trabajo es mostrar la percepción que estos profesionales tienen sobre las diferentes herramientas y soportes online que los departamentos de Comunicación de estos clubes emplean en su actividad diaria con los medios.AbstractThe FC Barcelona and Real Madrid CF have changed their communicative management model, especially in its relationship with the media. Favored by the introduction of ICT, Communication departments of these entities constitute gatekeeper to control and issue, through their own media, such as television and radio stations and media own online, the information that they generate. Thus, controlling broadcast messages and their target audiences directly without the intermediation of the mainstream media, conditioning routines productive sports journalists.The aim of this paper is to show the perception that these professionals have about the different tools and online media Communication departments to use these clubs in their daily activities with the media.

  11. Methods of Assessing Noise Nuisance of Real Estate Surroundings

    Directory of Open Access Journals (Sweden)

    Szopińska Kinga

    2016-03-01

    Full Text Available Testing what factors create the market value of real estate is key information when preparing property valuations as well as other opinions and professional evaluations on the basis of which court verdicts or administrative decisions are made. One of the factors influencing the value of some real estate is the level of noise present in the surroundings, which can lead to the occurrence of noise nuisance negatively affecting social relations.

  12. Los ocupantes de tierras en la Norpatagonia. Los Inspectores nacionales, el colono ideal y el poblador real al comenzar el siglo XX

    Directory of Open Access Journals (Sweden)

    Blanco, Graciela

    2016-12-01

    Full Text Available El presente trabajo realiza una aproximación a los pobladores que se asentaron en el norte de la Patagonia Argentina, particularmente en el Territorio de Río Negro, a partir de los informes de inspección realizados por funcionarios de la Dirección Nacional de Tierras en los años 1904, 1910 y 1920-21. Estos informes no abarcan la totalidad del territorio, inspeccionándose en esos años distintas zonas, particularmente las destinadas a funcionar como colonias o reservas –Conesa, Choele Choel, Frias, El Cuy, Valcheta-. Los mismos dan cuenta de los pobladores, la forma de tenencia de la tierra, la producción y las inversiones realizadas, clasificando y calificando a los pobladores de acuerdo a diferentes variables. El relato construido por estos inspectores resultaba el insumo más importante a la hora de decidir el acceso a la tierra. Se estudian los informes que estos agentes estatales producían, caracterizando las condiciones del poblamiento y puesta en producción de la región por parte de los pequeños productores de ganado menor o crianceros, complementando esas fuentes con la prensa regional y la producción existente sobre el tema.

  13. Year 2000 assessment report, Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Weir, D.

    1998-04-21

    The purpose of this report is to advise managers on the status of Year 2000 readiness at the Laboratory and provide a summary of critical issues to be addressed in order to ensure that the Year 2000 date rollover will not disrupt Laboratory Operations. The Laboratory`s Year 2000 council members are in the first phase of Year 2000 plans: gathering data and assessing the status of their divisions or programs. This first snapshot of the Laboratory Year 2000 readiness assessment is expected to grow and change over time as more refined assessments, plans, and schedules are developed and as more information becomes available. Here are findings to date: (1) Embedded systems` status not known. (2) Preliminary cost estimates for Year 2000 repairs, testing, and implementation are estimated to be at least $5.9 million, not including embedded systems. (3) The Laboratory is required to make unavoidable purchases of Year 2000-compliant products. (4) The Year 2000 short-term issue forces some long-term transition plans to be set aside. (5) The Laboratory is at risk for the following consequences if they can`t demonstrate an active Year 2000 program: risk of system failures; potential funding freezes by the OMB and DOE; legal liabilities; and risk to the UC contract. (6) The deadline for this project is immutable. (7) DOE is continually increasing reporting requirements, expanding from only DOE mission-essential to all operations. (7) DOE audit criticizes the Laboratory`s mission-essential systems planning.

  14. Real options as an alternative methodology to assess investment projects Las opciones reales como metodología alternativa en la evaluación de proyectos de inversión

    Directory of Open Access Journals (Sweden)

    Raúl Enrique Aristizábal Velásquez

    2012-12-01

    Full Text Available This paper aims to broaden the applicability of the assessment methodology of investment projects through real options as a key element for investment decision making. Traditional project valuation methodologies are described and their gaps, which special characteristic is uncertainty, are presented. A parallel between financial and real options that could be used for valuation is made, using the binomial tree method. Finally, a case study in the construction sector shows a project valuation using expand and waiting options.Este trabajo busca ampliar la aplicabilidad de la metodología de valoración de proyectos de inversión por medio de opciones reales como un elemento fundamental al momento de tomar una decisión de si se debe invertir o no. Se hace un recorrido por las técnicas tradicionales para valorar un proyecto de inversión y se plantean los vacíos que estos dejan, con respecto a proyectos en los que su principal característica es la incertidumbre. Se realiza un paralelo entre las opciones financieras y las opciones reales que per- mita valorar, utilizando la metodología de los árboles binomiales. Por último, se elabora un caso del que se plantea valorar una opción de espera y una opción de expandir de manera conjunta en el sector de la construcción.

  15. Real-time traveler information market assessment white paper.

    Science.gov (United States)

    2010-02-22

    This report takes a multi-modal look at the lay of the land of the real-time traveler information : market in the United States. This includes identification and characterization of the gaps in the : domestic industry with respect to data cover...

  16. Multimedia contaminant environmental exposure assessment methodology as applied to Los Alamos, New Mexico

    International Nuclear Information System (INIS)

    Whelan, G.; Thompson, F.L.; Yabusaki, S.B.

    1983-02-01

    The MCEA (Multimedia Contaminant Environmental Exposure Assessment) methodology assesses exposures to air, water, soil, and plants from contaminants released into the environment by simulating dominant mechanisms of contaminant migration and fate. The methodology encompasses five different pathways (i.e., atmospheric, terrestrial, overland, subsurface, and surface water) and combines them into a highly flexible tool. The flexibility of the MCEA methodology is demonstrated by encompassing two of the pathways (i.e., overland and surface water) into an effective tool for simulating the migration and fate of radionuclides released into the Los Alamos, New Mexico region. The study revealed that: (a) the 239 Pu inventory in lower Los Alamos Canyon increased by approximately 1.1 times for the 50-y flood event; (b) the average contaminant 239 Pu concentrations (i.e., weighted according to the depth of the respective bed layer) in lower Los Alamos Canyon for the 50-y flood event decreased by 5.4%; (c) approx. 27% of the total 239 Pu contamination resuspended from the entire bed (based on the assumed cross sections) for the 50-y flood event originated from lower Pueblo Canyon; (d) an increase in the 239 Pu contamination of the bed followed the general deposition patterns experienced by the sediment in Pueblo-lower Los Alamos Canyon; likewise, a decrease in the 239 Pu contamination of the bed followed general sediment resuspension patterns in the canyon; (e) 55% of the 239 Pu reaching the San Ildefonso Pueblo in lower Los Alamos Canyon originated from lower Los Alamos Canyon; and (f) 56% of the 239 Pu contamination reaching the San Ildefonso Pueblo in lower Los Alamos Canyon was carried through towards the Rio Grande. 47 references, 41 figures, 29 tables

  17. Assessment of real driving emissions via portable emission measurement system

    Science.gov (United States)

    Clenci, A.; Sălan, V.; Niculescu, R.; Iorga-Simăn, V.; Zaharia, C.

    2017-10-01

    The European Commission approved a so-called Real Driving Emission (RDE) test in response to the criticisms to the current driving cycle used at chassis dyno for homologation purpose (NEDC): it is considered outdated and misleading since air pollutants in real driving conditions are considerably higher than the certification thresholds. So, what’s at stake is the air quality which degraded continuously despite the ever-increasing severity of the regulations during the last almost three decades. Thus, from September 2017, the RDE test will become part of the type approval process for all cars sold in Europe. As its name points out, it will include “real world driving” using a portable emissions measurement system (PEMS). The paper presents the RDE features (PEMS mounting, testing environment, boundary conditions, driving dynamics) and presents a case study on the influence of the driving style upon the tail-pipe emissions under the RDE testing. The results presented in the paper issued from the existing cooperation on this topic between University of Pitesti and Renault Technologie Roumanie

  18. Los libros de obra del palacio de la Almudaina y su relación con la Rentas Reales de la Procuración Real del Reino de Mallorca, primer tercio del siglo XIV

    Directory of Open Access Journals (Sweden)

    María Llompart Bibiloni

    2013-07-01

    Full Text Available El palacio de la Almudaina es una de las principales obras urbanísticas proyectadas por Jaime II de Mallorca, que empezaron hacia 1305, y no acabaron hasta 1315-1316. El presente artículo se centra en el estudio de tres libros contables que se encuentran en el Archivo Histórico de Mallorca relativos a dichas obras, en concreto de los años 1309, 1310 y 1313. Dichos registros nos permiten conocer, en detalle, no solo los costes de construcción y remodelación de dicha obra emblemática, sino también la manera de trabajar en la isla a principios del siglo XIV. Se analizan los costes de maestros y profesionales, mano de obra no cualificada, mujeres y esclavos, así como los materiales contabilizados, las fuentes de financiación utilizadas y su relación con los ingresos y gastos de la Procuración Real de Mallorca en dicho periodo. Estos Llibres de la Almudayna son los documentos más antiguos, que han llegado a nuestros días, referidos a unas obras de tales dimensiones en el Reino de Mallorca y son una fuente fiable de datos útiles para la investigación histórica de esa época.

  19. Real-time safety risk assessment based on a real-time location system for hydropower construction sites.

    Science.gov (United States)

    Jiang, Hanchen; Lin, Peng; Fan, Qixiang; Qiang, Maoshan

    2014-01-01

    The concern for workers' safety in construction industry is reflected in many studies focusing on static safety risk identification and assessment. However, studies on real-time safety risk assessment aimed at reducing uncertainty and supporting quick response are rare. A method for real-time safety risk assessment (RTSRA) to implement a dynamic evaluation of worker safety states on construction site has been proposed in this paper. The method provides construction managers who are in charge of safety with more abundant information to reduce the uncertainty of the site. A quantitative calculation formula, integrating the influence of static and dynamic hazards and that of safety supervisors, is established to link the safety risk of workers with the locations of on-site assets. By employing the hidden Markov model (HMM), the RTSRA provides a mechanism for processing location data provided by the real-time location system (RTLS) and analyzing the probability distributions of different states in terms of false positives and negatives. Simulation analysis demonstrated the logic of the proposed method and how it works. Application case shows that the proposed RTSRA is both feasible and effective in managing construction project safety concerns.

  20. Environmental Assessment for Electrical Power System Upgrades at Los Alamos National Laboratory, Los Alamos, New Mexico - Final Document

    Energy Technology Data Exchange (ETDEWEB)

    N/A

    2000-03-09

    The ''National Environmental Policy Act of 1969'' (NEPA) requires Federal agency officials to consider the environmental consequences of their proposed actions before decisions are made. In complying with NEPA, the United States (U.S.) Department of Energy (DOE) follows the Council on Environmental Quality (CEQ) regulations (40 Code of Federal Regulations [CFR] 1500-1508) and DOE's NEPA implementing procedures (10 CFR 1021). The purpose of an Environmental Assessment (EA) is to provide Federal decision makers with sufficient evidence and analysis to determine whether to prepare an Environmental Impact Statement (EIS) or issue a Finding of No Significant Impact. In this case, the DOE decision to be made is whether to construct and operate a 19.5-mile (mi) (31-kilometer [km]) electric transmission line (power line) reaching from the Norton Substation, west across the Rio Grande, to locations within the Los Alamos National Laboratory (LANL) Technical Areas (TAs) 3 and 5 at Los Alamos, New Mexico. The construction of one electric substation at LANL would be included in the project as would the construction of two line segments less than 1,200 feet (ft) (366 meters [m]) long that would allow for the uncrossing of a portion of two existing power lines. Additionally, a fiber optics communications line would be included and installed concurrently as part of the required overhead ground conductor for the power line. The new power line would improve the reliability of electric service in the LANL and Los Aktrnos County areas as would the uncrossing of the crossed segments of the existing lines. Additionally, installation of the new power line would enable the LANL and the Los Alamos County electric grid, which is a shared resource, to be adapted to accommodate the future import of increased power when additional power service becomes available in the northern New Mexico area. Similarly, the fiber optics line would allow DOE to take advantage of

  1. The Equilibrium Real Exchange Rate of the Malagasy Franc; Estimation and Assessment

    OpenAIRE

    John Cady

    2003-01-01

    Employing cointegration techniques, the long-run determinants of Madagascar's real exchange rate are examined from a stock-flow perspective. The long-run behavior of the real effective exchange rate is explained by the net foreign asset position and factors affecting trade flows. An index of the long-run equilibrium real exchange rate is developed to assess the degree of misalignment. The general conclusions are that the Malagasy franc has experienced significant misalignment in the past, but...

  2. Applying real options analysis to assess cleaner energy development strategies

    International Nuclear Information System (INIS)

    Cheng, Ching-Tsung; Lo, Shang-Lien; Lin, Tyrone T.

    2011-01-01

    The energy industry, accounts for the largest portion of CO 2 emissions, is facing the issue of compliance with the national clean energy policy. The methodology for evaluating the energy mix policy is crucial because of the characteristics of lead time embedded with the power generation facilities investment and the uncertainty of future electricity demand. In this paper, a modified binomial model based on sequential compound options, which may account for the lead time and uncertainty as a whole is established, and a numerical example on evaluating the optional strategies and the strategic value of the cleaner energy policy is also presented. It is found that the optimal decision at some nodes in the binomial tree is path dependent, which is different from the standard sequential compound option model with lead time or time lag concept. The proposed modified binomial sequential compound real options model can be generalized and extensively applied to solve the general decision problems that deal with the long lead time of many government policies as well as capital intensive investments. - Highlights: → Introducing a flexible strategic management approach for government policy making. → Developing a modified binomial real options model based on sequential compound options. → Proposing an innovative model for managing the long term policy with lead time. → Applying to evaluate the options of various scenarios of cleaner energy strategies.

  3. La Administración Real en los Condados de Rosellón y Cerdaña (1600-1640

    Directory of Open Access Journals (Sweden)

    Miguel Ángel MARTÍNEZ RODRÍGUEZ

    2009-10-01

    Full Text Available RESUMEN: Durante los últimos años he investigado los diferentes niveles de la administración real en Cataluña, prestando una atención especial al funcionamiento de la justicia. Pero hace aproximadamente un par de años decidí concentrarme en el estudio de los altos cargos en estos territorios, es decir, en la administración real en el Rosellón y la Cerdaña. Para ello era imprescindible estudiar los gobernadores de dichos condados y los procuradores reales, que pertenecían a familias muy conocidas. Este último cargo fue patrimonializado por la familia Llupià. También me he preocupado por conocer las interminables actividades bélicas, que tanto caracterizan su trayectoria profesional, contra el ejército francés. Hecho de por sí muy relevante, ya que muchos de ellos desarrollaron su cursus honorum en esta candente zona fronteriza. Estos oficiales también debían tener unos imprescindibles conocimientos jurídicos, cualidades que no garantizaban por ellas mismas la promoción, pero que no por ello se tenían que desdeñar. Sus lazos familiares y sus relaciones sociales eran asimismo importantes para conseguir su anhelada proyección profesional. Esta información tan relevante se puede observar con claridad durante el proceso de selección, cuando cada candidato muestra sus conexiones sociales, las cuales le capacitan para optar a los máximos cargos de responsabilidad en los condados. El Consejo de Aragón y los virreyes siempre tienen en cuenta, de una forma u otra, los servicios familiares de los pretendientes. Cargos estos que no representaban la meta final para sus ocupantes. La administración real en Cataluña era más atractiva y normalmente mejor retribuida. Pero como era realmente difícil acceder directamente a los mismos era aconsejable intentar conseguir estos cargos en los condados, aunque no estuvieran tan bien retribuidos.ABSTRACT: During the last years I’ve done research into the different levels of the royal

  4. Personality Assessment for Employee Development: Ivory Tower or Real World?

    Science.gov (United States)

    Moyle, Penny; Hackston, John

    2018-06-22

    The acceptance and popularity of personality assessments in organizational contexts has grown enormously over the last 40 years. Although these are used across many applications, such as executive coaching, team building, and hiring and promotion decisions, the focus of most published research on the use of personality assessments at work is biased toward assessment for employee selection. Reviews have therefore tended to use criteria that are appropriate for selection, neglecting the additional and different criteria that are important in relation to employee development. An illustration of the often-discussed scientist-practitioner divide is that the Myers-Briggs Type Indicator is the most widely known and used personality assessment in organizations, despite harsh criticism by the academic community. This article reviews this debate, and draws implications for the appropriate choice of personality assessments for use in individual and team development, and a new direction for scientific research.

  5. Relación de largo plazo y análisis de causalidad y sensibilidad entre los salarios reales y la productividad laboral en el sector manufacturero a partir de cifras de los departamentos en Colombia

    Directory of Open Access Journals (Sweden)

    Jhon Alexander Méndez Sayago

    2014-09-01

    Full Text Available Este artículo se enfoca en identificar la relación entre los salarios y la productividad. Para comprobar si existe una relación de largo plazo entre estas variables, se realizan pruebas de raíz unitaria y cointegración para determinar si las series comparten tendencias estocásticas comunes. También se estimó un modelo de vectores autorregresivos (VAR para realizar un análisis de causalidad y sensibilidad, y así determinar cuál es el efecto futuro de los choques en cualquier variable del sistema, sobre ella misma y sobre la otra. Para el ejercicio empírico, se emplearon las series de productividad y salarios de 24 departamentos de Colombia, calculadas a partir de la información de la encuesta anual manufacturera. Los hallazgos empíricos permiten concluir que en Colombia existe un conflicto en la distribución de la riqueza porque los cambios en la productividad no se reflejan en incrementos de los salarios reales de los trabajadores. Por otra parte, a los empresarios no les conviene aumentar el salario real porque ese incremento no tiene un efecto futuro positivo sobre la productividad.******This article focuses on identifying the relation between wages and productivity. To demonstrate if there is a long-term relation between these variables, unit root and cointegration tests were applied to determine if the series shared common stochastic tendencies. A vector autoregressive model (VAR was used to do a causality and sensitivity analysis to determine the future effect of the shocks in any variable of the system, on itself and others. To conduct the empirical exercise, series of productivity and wages from 24 Colombian regions were used, which were calculated from the annual manufacturing survey. The empirical findings allow to conclude that a distribution of wealth conflict exists in Colombia because changes in productivity are not reflected on workers’ real salaries growths. On the other hand, increasing the actual wage is not

  6. Use of ecotoxicological screening action levels in ecological risk assessment at Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Ferenbauah, R.; Ebinger, M.; Gallegos, A.; Hansen, W.; Myers, O.; Wenzel, W.

    1995-01-01

    Regulatory drivers found in several environmental statutes require that ecological risk assessment and Natural Resource Damage Assessment be performed to assess potential environmental impact from contaminated sites and from proposed remedial alternatives. At Los Alamos National Laboratory, the initial phase of the ecological risk assessment process required preliminary evaluation of contaminated sites to determine whether potential for ecological impact exists. The preliminary evaluations were made using Ecotoxicological Screening Action Levels (ESALS) calculated as a function of reference toxicity dose, body weight, food/water/air intake, and fraction of soil intake with food. Reference toxicity doses were derived from the Environmental Protection Agency Integrated Risk Information System (IRIS) and Health Effects Assessment Summary Tables (HEAST) toxicology databases. Other parameters required for ESAL calculations were derived from physiological, metabolic, and behavioral data available in the literature. The Los Alamos ESALs were derived for guilds of animals with similar behavioral patterns, which were identified from natural resource survey data collected at Los Alamos. Subsequent to development of Ecotoxicological Screening Action Levels, Hazard Quotients, which are ratios of soil concentrations to Ecotoxicological Screening Action Levels, were calculated for potential contaminants of concern. The Hazard Quotients were used to identify which potential contaminants of concern should be evaluated further for ecological impact. There is potential for ecological impact when the Hazard Quotient is equal to or greater than one

  7. Investigation of the Adaptability of Transient Stability Assessment Methods to Real-Time Operation

    DEFF Research Database (Denmark)

    Weckesser, Johannes Tilman Gabriel; Jóhannsson, Hjörtur; Sommer, Stefan

    2012-01-01

    In this paper, an investigation of the adaptability of available transient stability assessment methods to real-time operation and their real-time performance is carried out. Two approaches based on Lyapunov’s method and the equal area criterion are analyzed. The results allow to determine...

  8. Environmental assessment for the proposed CMR Building upgrades at the Los Alamos National Laboratory, Los Alamos, New Mexico. Final document

    International Nuclear Information System (INIS)

    1997-01-01

    In order to maintain its ability to continue to conduct uninterrupted radioactive and metallurgical research in a safe, secure, and environmentally sound manner, the US Department of Energy (DOE) proposes to upgrade the Los Alamos National Laboratory (LANL) Chemistry and Metallurgy Research (CMR) Building. The building was built in the early 1950s to provide a research and experimental facility for analytical chemistry, plutonium and uranium chemistry, and metallurgy. Today, research and development activities are performed involving nuclear materials. A variety of radioactive and chemical hazards are present. The CMR Building is nearing the end of its original design life and does not meet many of today's design codes and standards. The Proposed Action for this Environmental Assessment (EA) includes structural modifications to some portions of the CMR Building which do not meet current seismic criteria for a Hazard Category 2 Facility. Also included are upgrades and improvements in building ventilation, communications, monitoring, and fire protection systems. This EA analyzes the environmental effects of construction of the proposed upgrades. The Proposed Action will have no adverse effects upon agricultural and cultural resources, wetlands and floodplains, endangered and threatened species, recreational resources, or water resources. The Proposed Action would have negligible effects on human health and transportation, and would not pose a disproportionate adverse health or environmental impact on minority or low-income populations within an 80 kilometer (50 mile) radius of the CMR Building

  9. Environmental assessment for the proposed CMR Building upgrades at the Los Alamos National Laboratory, Los Alamos, New Mexico. Final document

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1997-02-04

    In order to maintain its ability to continue to conduct uninterrupted radioactive and metallurgical research in a safe, secure, and environmentally sound manner, the US Department of Energy (DOE) proposes to upgrade the Los Alamos National Laboratory (LANL) Chemistry and Metallurgy Research (CMR) Building. The building was built in the early 1950s to provide a research and experimental facility for analytical chemistry, plutonium and uranium chemistry, and metallurgy. Today, research and development activities are performed involving nuclear materials. A variety of radioactive and chemical hazards are present. The CMR Building is nearing the end of its original design life and does not meet many of today`s design codes and standards. The Proposed Action for this Environmental Assessment (EA) includes structural modifications to some portions of the CMR Building which do not meet current seismic criteria for a Hazard Category 2 Facility. Also included are upgrades and improvements in building ventilation, communications, monitoring, and fire protection systems. This EA analyzes the environmental effects of construction of the proposed upgrades. The Proposed Action will have no adverse effects upon agricultural and cultural resources, wetlands and floodplains, endangered and threatened species, recreational resources, or water resources. The Proposed Action would have negligible effects on human health and transportation, and would not pose a disproportionate adverse health or environmental impact on minority or low-income populations within an 80 kilometer (50 mile) radius of the CMR Building.

  10. Floodplain Assessment for the Middle Los Alamos Canyon Aggregate Area Investigations in Technical Area 02 at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Hathcock, Charles Dean [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-05-22

    The proposed action being assessed in this document occurs in TA-02 in the bottom of Los Alamos Canyon. The DOE proposes to conduct soil sampling at AOC 02-011 (d), AOC 02- 011(a)(ii), and SWMU 02-005, and excavate soils in AOC 02-011(a)(ii) as part of a corrective actions effort. Additional shallow surface soil samples (soil grab samples) will be collected throughout the TA-02 area, including within the floodplain, to perform ecotoxicology studies (Figures 1 and 2). The excavation boundaries in AOC 02-011(a)(ii) are slightly within the delineated 100-year floodplain. The project will use a variety of techniques for soil sampling and remediation efforts to include hand/digging, standard hand auger/sampling, excavation using machinery such as backhoe and front end loader and small drill rig. Heavy equipment will traverse the floodplain and spoils piles will be staged in the floodplain within developed or previously disturbed areas (e.g., existing paved roads and parking areas). The project will utilize and maintain appropriate best management practices (BMPs) to contain excavated materials, and all pollutants, including oil from machinery/vehicles. The project will stabilize disturbed areas as appropriate at the end of the project.

  11. Assessing acupuncture effect in the real world study

    Directory of Open Access Journals (Sweden)

    Qi-Wen Zhang

    2017-04-01

    Full Text Available Acupuncture, with its unique set of theories and its evident results in clinical practice is an important part of traditional Chinese medicine (TCM, and gaining recognition worldwide for the past few years. Although acupuncture treatment is generally accepted by the public, a few western researchers believe that sufficient evidence of its efficiency is still currently lacking, therefore creating a challenge of its acceptance on a wider scale. This article suggests the concepts of acupuncture behind clinical researches by reviewing the clinical researches done, analyzing the existing problems, and integrating real life acupuncture into the research process. By increasing the credibility of acupuncture, its reach can be extended globally and to more countries and regions.

  12. Environmental Assessment for the High Explosives Wastewater Treatment Facility, Los Alamos National Laboratory, Los Alamos, New Mexico

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1995-08-03

    The Department of Energy (DOE) has identified a need to improve the management of wastewater resulting from high explosives (HE) research and development work at Los Alamos National Laboratory (LANL). LANL`s current methods off managing HE-contaminated wastewater cannot ensure that discharged HE wastewater would consistently meet the Environmental Protection Agency`s (EPA`s) standards for wastewater discharge. The DOE needs to enhance He wastewater management to e able to meet both present and future regulatory standards for wastewater discharge. The DOE also proposes to incorporate major pollution prevention and waste reduction features into LANL`s existing HE production facilities. Currently, wastewater from HE processing buildings at four Technical Areas (TAs) accumulates in sumps where particulate HE settles out and barium is precipitated. Wastewater is then released from the sumps to the environment at 15 permitted outfalls without treatment. The released water may contain suspended and dissolved contaminants, such as HE and solvents. This Environmental Assessment (EA) analyzes two alternatives, the Proposed Action and the Alternative Action, that would meet the purpose and need for agency action. Both alternatives would treat all HE process wastewater using sand filters to remove HE particulates and activated carbon to adsorb organic solvents and dissolved HE. Under either alternative, LANL would burn solvents and flash dried HE particulates and spent carbon following well-established procedures. Burning would produce secondary waste that would be stored, treated, and disposed of at TA-54, Area J. This report contains the Environmental Assessment, as well as the Finding of No Significant Impact and Floodplain Statement of Findings for the High Explosives Wastewater Treatment Facility.

  13. Environmental Assessment for the High Explosives Wastewater Treatment Facility, Los Alamos National Laboratory, Los Alamos, New Mexico

    International Nuclear Information System (INIS)

    1995-01-01

    The Department of Energy (DOE) has identified a need to improve the management of wastewater resulting from high explosives (HE) research and development work at Los Alamos National Laboratory (LANL). LANL's current methods off managing HE-contaminated wastewater cannot ensure that discharged HE wastewater would consistently meet the Environmental Protection Agency's (EPA's) standards for wastewater discharge. The DOE needs to enhance He wastewater management to e able to meet both present and future regulatory standards for wastewater discharge. The DOE also proposes to incorporate major pollution prevention and waste reduction features into LANL's existing HE production facilities. Currently, wastewater from HE processing buildings at four Technical Areas (TAs) accumulates in sumps where particulate HE settles out and barium is precipitated. Wastewater is then released from the sumps to the environment at 15 permitted outfalls without treatment. The released water may contain suspended and dissolved contaminants, such as HE and solvents. This Environmental Assessment (EA) analyzes two alternatives, the Proposed Action and the Alternative Action, that would meet the purpose and need for agency action. Both alternatives would treat all HE process wastewater using sand filters to remove HE particulates and activated carbon to adsorb organic solvents and dissolved HE. Under either alternative, LANL would burn solvents and flash dried HE particulates and spent carbon following well-established procedures. Burning would produce secondary waste that would be stored, treated, and disposed of at TA-54, Area J. This report contains the Environmental Assessment, as well as the Finding of No Significant Impact and Floodplain Statement of Findings for the High Explosives Wastewater Treatment Facility

  14. The impact of gated Communities on property values: evidence of changes in real estate markets -Los Angeles, 1980-2000

    Directory of Open Access Journals (Sweden)

    Renaud Le Goix

    2007-05-01

    Full Text Available The paper focuses on how gated communities, as private means of providing public infrastructure and security, real estate products and club-economies, produce changes in housing market patterns. Based on an empirical study of Los Angeles (California data, it aims to trace to what extent gates and walls favor property values and if the presence of gated communities produces over time (1980-2000 a deterrent effect on non-gated properties abutting the enclave, or close to it. Resulting from a demand for security, gated communities are a leading offer from the homebuilding industry. But their spread emerges from a partnership between local governments and land developers. Both agree to charge the homebuyer with the cost of urban sprawl (construction and maintenance costs of infrastructure within the gates. Such a structuring of residential space is particularly desirable on the urban edges, where the cost of urban sprawl exceeds the financial assets of local public authorities. New private developments provide local governments with new wealthy taxpayers at almost no cost. As compensation, the homebuyer is granted private and exclusive access to sites and amenities (lakes, beaches, etc.. Such exclusivity favors the location rent, and usually positively affects the property values within the gated enclaves. But it is also assumed that operating cost of private governance are paid for by the increase of property values. Market failure nevertheless occurs when costs rise above sustainable levels compared to property values. Changes produced by gates yield to at least two outcomes. At first sight, residential enclosures produce a price premium, thus being a smart investment. Furthermore, gated communities might well be able to generate enough property value to pay off the price of private governance. But this analysis holds only on a short term basis. In the long term, larger and wealthier gated communities are successful in shielding their property

  15. Goodness of Fit of Skills Assessment Approaches: Insights from Patterns of Real vs. Synthetic Data Sets

    Science.gov (United States)

    Beheshti, Behzad; Desmarais, Michel C.

    2015-01-01

    This study investigates the issue of the goodness of fit of different skills assessment models using both synthetic and real data. Synthetic data is generated from the different skills assessment models. The results show wide differences of performances between the skills assessment models over synthetic data sets. The set of relative performances…

  16. ARAC: A flexible real-time dose consequence assessment system

    International Nuclear Information System (INIS)

    Ellis, J.S.; Sullivan, T.J.

    1993-01-01

    Since its beginning, the Atmospheric Release Advisory Capability (ARAC), an emergency radiological dose assessment service of the US Government, has been called on to do consequence assessments for releases into the atmosphere of radionuclides and a variety of other substances. Some of the more noteworthy emergency responses have been for the Three Mile Island and Chernobyl nuclear power reactor accidents, and more recently, for a cloud of gases from a rail-car spill into the Sacramento river of the herbicide metam sodium, smoke from hundreds of burning oil wells in Kuwait, and ash clouds from the eruption of Mt. Pinatubo. The spatial scales of these responses range from local, to regional, to global, and the response periods from hours, to weeks, to months. Because of the variety of requirements of each unique assessment, ARAC has developed and maintains a flexible system of people, computer software and hardware

  17. Anxiety in Asperger's Syndrome: Assessment in Real Time

    Science.gov (United States)

    Hare, Dougal J.; Wood, Christopher; Wastell, Sarah; Skirrow, Paul

    2015-01-01

    Anxiety is a major problem for many people with Asperger's syndrome who may have qualitatively different fears from a non-Asperger's syndrome population. Research has relied on measures developed for non-Asperger's syndrome populations that require reporting past experiences of anxiety, which may confound assessment in people with Asperger's…

  18. Innovative real time simulation training and nuclear probabilistic risk assessment

    International Nuclear Information System (INIS)

    Reisinger, M.F.

    1991-01-01

    Operator errors have been an area of public concern for the safe operation of nuclear power plants since the TMI2 incident. Simply stated, nuclear plants are very complex systems and the public is skeptical of the operators' ability to comprehend and deal with the vast indications and complexities of potential nuclear power plant events. Prior to the TMI2 incident, operator errors and human factors were not included as contributing factors in the Probabilistic Risk Assessment (PRA) studies of nuclear power plant accidents. More recent efforts in nuclear risk assessment have addressed some of the human factors affecting safe nuclear plant operations. One study found four major factors having significant impact on operator effectiveness. This paper discusses human factor PRAs, new applications in simulation training and the specific potential benefits from simulation in promoting safer operation of future power plants as well as current operating power plants

  19. Real-Time Assessment and Diagnosis of Process Operating Performance

    Directory of Open Access Journals (Sweden)

    Shabnam Sedghi

    2017-04-01

    Full Text Available Over time, the performance of processes may deviate from the initial design due to process variations and uncertainties, making it necessary to develop systematic methods for online optimality assessment based on routine operating process data. Some processes have multiple operating modes caused by the set point change of the critical process variables to achieve different product specifications. On the other hand, the operating region in each operating mode can alter, due to uncertainties. In this paper, we will establish an optimality assessment framework for processes that typically have multi-mode, multi-region operations, as well as transitions between different modes. The kernel density approach for mode detection is adopted and improved for operating mode detection. For online mode detection, the model-based clustering discriminant analysis (MclustDA approach is incorporated with some a priori knowledge of the system. In addition, multi-modal behavior of steady-state modes is tackled utilizing the mixture probabilistic principal component regression (MPPCR method, and dynamic principal component regression (DPCR is used to investigate transitions between different modes. Moreover, a probabilistic causality detection method based on the sequential forward floating search (SFFS method is introduced for diagnosing poor or non-optimum behavior. Finally, the proposed method is tested on the Tennessee Eastman (TE benchmark simulation process in order to evaluate its performance.

  20. Assessment of greater-than-Class C waste at Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Shuman, R.; Jennrich, E.A.; Merrell, G.B.

    1991-02-01

    Department of Energy (DOE) Order 5820.2A regulates the onsite disposal of low-level radioactive waste (LLW) at all DOE facilities. Among its stipulations, the Order states that ''Disposition of wastes designated as greater-than-Class C, as defined in 10 CFR 61.55 must be handled as special cases. Disposal systems for such waste must be justified by a specific performance assessment.'' Los Alamos National Laboratory (LANL) personnel have undertaken a review and performance assessment of LLW disposal at its Area-G disposal facility, which is described in this report

  1. Una revisión crítica de las técnicas de filtrado para la teoría de los ciclos económicos reales

    Directory of Open Access Journals (Sweden)

    Lopera Sierra John Fernando

    2010-12-01

    Full Text Available Este artículo presenta una revisión de diferentes investigaciones con respecto a dos elementos básicos de la teoría de los ciclos económicos reales: los factores que determinan los ciclos económicos y las técnicas de filtrado (estadísticas o económicas que permiten estimarlos. El trabajo concluye, al igual que otros estudios, que cuando se utilizan diferentes técnicas de filtrado es posible encontrar distintos hechos estilizados, lo cual condiciona las interpretaciones sobre los factores que determinan los ciclos.

  2. Assessing Change in High School Student Information Literacy Using the Tool for Real-Time Assessment of Information Literacy Skills

    Science.gov (United States)

    Kovalik, Cindy L.; Yutzey, Susan D.; Piazza, Laura M.

    2012-01-01

    Change in high school student information literacy (IL) knowledge and skills, from freshman year to senior year in high school was the focus of this quasi-experimental research project. Researchers used a free information literacy skills assessment tool entitled TRAILS (Tool for Real-time Assessment of Information Literacy Skills) to measure…

  3. Aquifers in coastal reclaimed lands - real world assessments

    Science.gov (United States)

    Saha, A.; Bironne, A.; Vonhögen-Peeters, L.; Lee, W. K.; Babovic, V. M.; Vermeulen, P.; van Baaren, E.; Karaoulis, M.; Blanchais, F.; Nguyen, M.; Pauw, P.; Doornenbal, P.

    2017-12-01

    Climate change and population growth are significant concerns in coastal regions around the world, where more than 30% of the world's population reside. The numbers continue to rise as coastal areas are increasingly urbanized. Urbanization creates land shortages along the coasts, which has spurred coastal reclamation activities as a viable solution. In this study, we focus on these reclamation areas; reclaimed areas in Singapore, and in the Netherlands, and investigate the potential of these reclaimed bodies as artificial aquifers that could attenuate water shortage problems in addition to their original purpose. We compare how the reclamation methods determine the hydrogeological characteristics of these manmade aquifers. We highlight similarities in freshwater lens development in the artificial shallow aquifers under natural recharge under diverse conditions, i.e. tropical and temperate zones, using numerical models. The characteristics and responses of these aquifers with dynamic freshwater-saltwater interface are contrasted against naturally occurring coastal aquifers where equilibrium was disturbed by anthropogenic activities. Finally, we assess the risks associated with subsidence and saltwater intrusion, combining measurements and numerical models, in case these aquifers are planned for Aquifer Storage and Recovery (ASR) or Managed Aquifer Recharge (MAR) strategies. Relative performances of some ASR schemes are simulated and compared in the reclaimed lands.

  4. Rate-base determination through real-time efficiency assessment

    International Nuclear Information System (INIS)

    Eckhardt, J.H.; Bishop, T.W.

    1990-01-01

    One of the main problems with nuclear power is the extremely high construction costs and long schedules for plant construction and start-up. It is unlikely that utility executives will risk their companies' financial health by committing the necessary capital resources given the prevailing uncertainties. For new nuclear plants to play a major role in preventing future electric supply shortages, the financial uncertainties associated with high construction costs must be minimized. To contain costs and maintain reasonable schedules for future plants, the utilities, vendors, the US Nuclear Regulatory Commission (NRC), and the state regulatory commissions can make specific changes. One of the key factors to reduce uncertainty and improve cost and schedule performance is for the state regulatory commissions to change the method of determining reasonable plant costs and placing those costs in the rate base. Currently, most state regulatory commissions assess the reasonableness of costs only after completion of construction, resulting in years of financial uncertainty and untimely conclusions as to what should have been done better

  5. Curiosidades vivas. Los animales de América y Filipinas en la Ménagerie real durante el siglo XVIIII

    Directory of Open Access Journals (Sweden)

    Gómez-Centurión Jiménez, Carlos

    2009-12-01

    Full Text Available The article analyzes the important role of animals from Spanish America and the Philippines in Royal zoological collections during the 18th Century. It studies not only the species that were included more frequently in the collections and the criteria for their selection, but also the political and lobbying mechanisms devised for their shipment to the Madrid Court. The article also describes the many obstacles that had to be overcome in order to ensure the survival of the animals in their transoceanic journey.El artículo analiza el importante papel desempeñado por los animales procedentes de la América española y de Filipinas en las colecciones zoológicas reales durante el siglo XVIII. Además de las especies que con mayor frecuencia estuvieron presentes en dichas colecciones y sus criterios de selección, se estudian los mecanismos clientelares y políticos que propiciaban su envío hasta la corte madrileña, así como los numerosos obstáculos que era necesario sortear para que los animales lograran sobrevivir a la travesía trans - oceánica.

  6. Unsupervised deep learning for real-time assessment of video streaming services

    NARCIS (Netherlands)

    Torres Vega, M.; Mocanu, D.C.; Liotta, A.

    2017-01-01

    Evaluating quality of experience in video streaming services requires a quality metric that works in real time and for a broad range of video types and network conditions. This means that, subjective video quality assessment studies, or complex objective video quality assessment metrics, which would

  7. Political-Philosophical Perspectives about the Notions of Indian, Inca, and Mestizo on the «Comentarios reales de los Incas»

    Directory of Open Access Journals (Sweden)

    Alejandro Javier Viveros Espinosa

    2016-11-01

    Full Text Available This essay posits certain political-philosophical perspectives on the Inca Garcilaso de la Vega’s Primera parte de los Comentarios reales de los Incas (1609. To this purpose we will develop two hermeneutical movements. The first refers to a theoretical and methodological questioning related to the notion of Indian as a discursive construction during colonial times in the Andes area. The second deploys a critical exercise grounded on the interaction between the notions of Indian, Inca, and Mestizo, which is focused on how they build alternative subjectivities. Both movements consolidate an interpretation about the Inca Garcilaso’s political-philosophical reflections, remarking his proposals of a bifurcated modern civilizational project in the New World.

  8. Low Energy Accelerator Laboratory Technical Area 53, Los Alamos National Laboratory. Environmental assessment

    International Nuclear Information System (INIS)

    1995-04-01

    This Environmental Assessment (EA) analyzes the potential environmental impacts that would be expected to occur if the Department of Energy (DOE) were to construct and operate a small research and development laboratory building at Technical Area (TA) 53 at the Los Alamos National Laboratory (LANL), Los Alamos, New Mexico. DOE proposes to construct a small building to be called the Low Energy Accelerator Laboratory (LEAL), at a previously cleared, bladed, and leveled quarter-acre site next to other facilities housing linear accelerator research activities at TA-53. Operations proposed for LEAL would consist of bench-scale research, development, and testing of the initial section of linear particle accelerators. This initial section consists of various components that are collectively called an injector system. The anticipated life span of the proposed development program would be about 15 years

  9. Chemical Exposure Assessment Program at Los Alamos National Laboratory: A risk based approach

    International Nuclear Information System (INIS)

    Stephenson, D.J.

    1996-01-01

    The University of California Contract And DOE Order 5480.10 require that Los Alamos National Laboratory (LANL) perform health hazard assessments/inventories of all employee workplaces. In response to this LANL has developed the Chemical Exposure Assessment Program. This program provides a systematic risk-based approach to anticipation, recognition, evaluation and control of chemical workplace exposures. Program implementation focuses resources on exposures with the highest risks for causing adverse health effects. Implementation guidance includes procedures for basic characterization, qualitative risk assessment, quantitative validation, and recommendations and reevaluation. Each component of the program is described. It is shown how a systematic method of assessment improves documentation, retrieval, and use of generated exposure information

  10. Investigation of the Adaptability of Transient Stability Assessment Methods to Real-Time Operation

    OpenAIRE

    Weckesser, Johannes Tilman Gabriel; Jóhannsson, Hjörtur; Sommer, Stefan; Østergaard, Jacob

    2012-01-01

    In this paper, an investigation of the adaptability of available transient stability assessment methods to real-time operation and their real-time performance is carried out. Two approaches based on Lyapunov’s method and the equal area criterion are analyzed. The results allow to determine the runtime of each method with respect to the number of inputs. Furthermore, it allows to identify, which method is preferable in case of changes in the power system such as the integration of distributed ...

  11. Ranking of options of real estate use by expert assessments mathematical processing

    Science.gov (United States)

    Lepikhina, O. Yu; Skachkova, M. E.; Mihaelyan, T. A.

    2018-05-01

    The article is devoted to the development of the real estate assessment concept. In conditions of multivariate using of the real estate method based on calculating, the integral indicator of each variant’s efficiency is proposed. In order to calculate weights of criteria of the efficiency expert method, Analytic hierarchy process and its mathematical support are used. The method allows fulfilling ranking of alternative types of real estate use in dependence of their efficiency. The method was applied for one of the land parcels located on Primorsky district in Saint Petersburg.

  12. Los conjuntos palaciegos reales de las Tierras Bajas Mayas del sur: una evaluación de los datos arqueológicos e iconográficos Royal palace complexes in Southern Maya Lowlands: evaluating archaeological and iconographical data

    Directory of Open Access Journals (Sweden)

    Kai Delvendahl

    2010-01-01

    Full Text Available Este artículo va a trazar algunas conclusiones de una evaluación de los aspectos físicos, espaciales, funcionales y sociales de los conjuntos palaciegos reales tomando en cuenta evidencia arqueológica e iconográfica. Para el componente iconográfico se analizaron representaciones de escenas palaciegas pintadas sobre 87 vasijas cilíndricas de cerámica, mientras que para el componente arqueológico se evaluó información de conjuntos palaciegos bien documentados como el Grupo Palaciego M7 de Aguateca, el Palacio de Palenque, Los 27 Escalones de Kohunlich, el Grupo 10L-2 de Copán, la Acrópolis Central de Tikal y el Grupo Gran Acrópolis de Calakmul. Uno de los objetivos generales de este trabajo es proporcionar un ejemplo de cómo se puede capitalizar la información que las escenas palaciegas proveen (al comparar el corpus iconográfico con el dato arqueológico. Esto permitiría plantear ideas más ajustadas sobre los aspectos físicos, espaciales, funcionales y sociales de los conjuntos palaciegos del Clásico Tardío en el área maya.This paper will present some conclusions of an evaluation of the physical, spatial, functional, and social aspects of Classic Maya royal palaces taking into account archaeological and iconographic evidence. For the iconographic evaluation, the analysis examined representations of palace-like ambience on 87 cylindrical ceramic vases, while the archaeological information includes data from the better documented palace groups of the Southern Maya Lowlands, including the Palace Group M7 of Aguateca, the Palace of Palenque, Los 27 Escalones of Kohunlich, Group 10L-2 of Copan, the Central Acropolis of Tikal and the Grand Acropolis Group of Calakmul. In comparing the iconographic corpus with the archaeological evidence, one of the general objectives of this presentation is to provide an example of how the information inherent in the palace scenes can be capitalized to propose more adjusted ideas about the

  13. Real-time Continuous Assessment Method for Mental and Physiological Condition using Heart Rate Variability

    Science.gov (United States)

    Yoshida, Yutaka; Yokoyama, Kiyoko; Ishii, Naohiro

    It is necessary to monitor the daily health condition for preventing stress syndrome. In this study, it was proposed the method assessing the mental and physiological condition, such as the work stress or the relaxation, using heart rate variability at real time and continuously. The instantanuous heart rate (HR), and the ratio of the number of extreme points (NEP) and the number of heart beats were calculated for assessing mental and physiological condition. In this method, 20 beats heart rate were used to calculate these indexes. These were calculated in one beat interval. Three conditions, which are sitting rest, performing mental arithmetic and watching relaxation movie, were assessed using our proposed algorithm. The assessment accuracies were 71.9% and 55.8%, when performing mental arithmetic and watching relaxation movie respectively. In this method, the mental and physiological condition was assessed using only 20 regressive heart beats, so this method is considered as the real time assessment method.

  14. DOE Los Alamos National Laboratory – PV Feasibility Assessment, 2015 Update, NREL Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Dean, Jesse [National Renewable Energy Lab. (NREL), Golden, CO (United States); Witt, Monica Rene [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-04-06

    This report summarizes solar and wind potential for Los Alamos National Laboratory (LANL). This report is part of the “Los Alamos National Laboratory and Los Alamos County Renewable Generation” study.

  15. Contaminación acústica en la zona 3 de la ciudad de Querétaro: comparación de los niveles de ruido reales y los apreciados por los habitantes

    Directory of Open Access Journals (Sweden)

    Ivan Peñaloza Pineda

    2016-01-01

    Full Text Available En este artículo se describen los daños ocasionados la contaminación acústica en distintos niveles, expuestos en diversos estudios científicos; se muestran mediciones de decibeles in situ, así como los resultados de un estudio exploratorio que expone la percepción respecto a la contaminación acústica de 168 habitantes de una zona determinada de la ciudad de Querétaro, con el objetivo de encontrar el grado de afectación percibida para determinar si hay concordancia al respecto. El presente artículo forma parte de una investigación encaminada al desarrollo de un producto orientado a la disminución del ruido en las viviendas. Nuestros hallazgos indican que, aunque cerca de 60% de los encuestados encuentra el ruido de la zona como “elevado”, e identifica los vehículos y las motocicletas como la fuente de ruido más molesta, al mismo tiempo no son conscientes de las afectaciones en el desempeño de sus actividades como consecuencia de los niveles de contaminación acústica en la zona.

  16. In-vivo assessment of whole-body radioisotope burdens at the Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Vasilik, D.G.; Aikin, I.C.

    1983-08-01

    The Los Alamos National Laboratory program for in-vivo measurements includes the capability for the whole-body assessment of body burdens for x-ray or gamma-ray emitting radioisotopes. This capability is an important part of the health and safety program at Los Alamos where a wide variety of radioisotopes are utilized. This report addresses the whole body portion of our in-vivo measurement capabilities. Whole-body measurements at Los Alamos make use of a hyperpure germanium (HpGe) detector and a lithium-drifted germanium [Ge(Li)] detector for identification and quantification of radioisotopes. Analysis results are interpreted in terms of two basic statistical measures of detection limits. One measure is called the minimum significant measured activity (MSMA), which is interpreted as meaning that there is some activity in the body. The second measure is called the minimum detectable true activity (MDTA), which is defined as the smallest amount of activity required to be in the body in order that a measurement of an individual can be expected to imply correctly the presence of activity with a predetermined degree of confidence. 7 references, 8 figures

  17. Hacer atractivo el aprendizaje de la matemática, insertando los contenidos dentro de modelos reales

    OpenAIRE

    Arancibia, Sara

    2004-01-01

    Diversos estudios sobre tecnologías educativas para la docencia superior, formulan la participación activa y aprendizajes significativos, complementado con trabajo interactivo y autoestima positiva. Investigadores en educación afirman que “Construimos significados cuando relacionamos las nuevas informaciones con nuestros esquemas previos de comprensión de la realidad”. Por tanto, se propone incluir los contenidos dentro de situaciones naturales que impliquen el enfrentamiento del alumno con t...

  18. Los ingenios de carpintería en la construcción del Monasterio de San Lorenzo el Real de El Escorial

    Directory of Open Access Journals (Sweden)

    Manuel José García Sanguino

    2008-01-01

    Full Text Available La considerable altura que fue alcanzando el Monasterio de San Lorenzo el Real de El Escorial requirió la construcción de grúas de madera para elevar del suelo los pesados bloques de granito gris de la Sierra de Guadarrama. Es en este preciso momento cuando algunos de los carpinteros, que trabajaban en tan insigne obra, pusieron al servicio de Felipe II su audacia y habilidad técnica. El análisis exhaustivo y riguroso de la documentación existente en la biblioteca del Monasterio de San Lorenzo de El Escorial, esclarece la autoría de la fabricación de estas máquinas o ingenios.The considerable height that the Monastery of San Lorenzo el Real de El Escorial was reaching, required the construction of wooden cranes to raise the heavy blocks of grey granite from the Guadarrama mountains. At that precise moment, some of the carpenters who were working on this notable construction, offered their courage and skills to Felipe II. The rigorous and comprehensive analysis of the existing documentation at the Royal Library in the Monastery clarifies who was responsible for the construction of those machines or devices.

  19. Los planes de estudio y el claustro de la Facultad de Farmacia en la Real Universidad de La Habana entre 1880 y 1898

    Directory of Open Access Journals (Sweden)

    Pilar Marchante Castellanos

    2009-04-01

    Full Text Available Aunque el plan de estudios de 1880, último que aplicó la Corona española en Cuba, representó un notable progreso para la organización de la enseñanza en la Universidad de La Habana, no introdujo de inicio cambios en la formación del profesional farmacéutico. La verdadera transformación se produjo al aplicarse la reforma de 1887, la cual tuvo como principal objetivo rediseñar las carreras de Farmacia y Medicina en la Real Universidad de La Habana. En este trabajo se presenta el plan de estudios de 1880 y el que se aprobó como resultado de la reforma de 1887 para la Facultad de Farmacia. Se hace además referencia a los profesores que ocuparon las diferentes cátedras y a los auxiliares que debieron asumir las vacantes en cada curso. Todos los catedráticos resultaron afectados de una u otra forma por las sucesivas medidas administrativas adoptadas en la Universidad, en virtud de la crítica situación política que afectó a la isla durante la vigencia del plan de 1880, agudizada al extremo después del estallido, en 1895, de la última guerra librada contra España por la independencia de Cuba.

  20. Modelado y simulación del comportamiento real de los componentes pasivos en el dominio de la frecuencia

    Directory of Open Access Journals (Sweden)

    Luis Arturo Herrera-Vega

    2014-12-01

    El presente documento pretende resumir una serie de modelos conceptuales simples desarrollados por varios autores que aproximan; de forma más precisa, el comportamiento de estos dispositivos al variar las frecuencias de operación, así como una breve descripción de los materiales utilizados en su construcción, con el objetivo de ampliar el panorama teórico para un mejor entendimiento y posterior caracterización de sistemas eléctricos.

  1. Alternative Assessment--Can Real-World Skills Be Tested? Policy Briefs.

    Science.gov (United States)

    Simon, Karen; Gregg, Soleil

    Many educators are shifting their teaching strategies and approaches to include more emphasis on critical thinking skills, the communication of ideas, a variety of approaches to content emphasizing varied student learning styles, and the need to draw explicit connections among topics for retention of learning. Real-world assessment measures, then,…

  2. A Real-Time Plagiarism Detection Tool for Computer-Based Assessments

    Science.gov (United States)

    Jeske, Heimo J.; Lall, Manoj; Kogeda, Okuthe P.

    2018-01-01

    Aim/Purpose: The aim of this article is to develop a tool to detect plagiarism in real time amongst students being evaluated for learning in a computer-based assessment setting. Background: Cheating or copying all or part of source code of a program is a serious concern to academic institutions. Many academic institutions apply a combination of…

  3. Determinación de esteroles en la fracción insaponificable del aceite de los frutos de la palma real cubana (Roystonea regia

    Directory of Open Access Journals (Sweden)

    David Marrero Delange

    2013-03-01

    Full Text Available Introducción: los esteroles han sido ampliamente estudiados por su importancia nutricional y farmacéutica. Sin embargo, para nuestro conocimiento, la composición de esteroles del aceite de los frutos de la palma real cubana (Roystonea regia no ha sido determinada hasta el momento. Objetivos: determinar la composición de esteroles que pudieran estar presentes en la fracción insaponificable del aceite de R. regia mediante CG-EM. Métodos: muestras de dos lotes de aceite de R. regia fueron sometidas al procedimiento para la determinación de esteroles establecido por el del Instituto de Nutracéuticos de los EE.UU., el cual consiste, fundamentalmente, en una saponificación con disolución de KOH/EtOH y posterior extracción con n-hexano de las fracciones insaponificables. Las fracciones obtenidas fueron analizadas por CG-EM como derivados TMS e identificadas por comparación de sus espectros con los de patrones comerciales y los de la base de espectros Wiley. Para la cuantificación se utilizó el colestano como patrón interno. Resultados: en la fracción insaponificable del aceite de R. regia se encontró un contenido total de esteroles de 66,1%; lo que representa un 0,14 % del aceite. La fracción de esteroles, estuvo compuesta principalmente por â -sitosterol (51,2 %, estigmasterol (9,6 %, campesterol (9,2 %, 24-metilen-cicloartanol (9,2 %, Ä5-avenasterol (8,9 %, cicloartanol (7,5 %; además de otros componentes minoritarios como cicloartenol, ã-sitosterol y colesterol. Conclusiones: se identificaron y se cuantificaron mediante CG-EM los esteroles de la fracción insaponificable del aceite de R. regia, en la cual el â-sitosterol resultó el componente mayoritario. Estos resultados son una contribución al estudio de la composición química de dicho aceite y pudieran avalar su posible utilidad nutricional y seguridad.

  4. Determinantes de los precios reales de las materias primas agrícolas. El papel de los inventarios y de los factores macroeconómicos (1960-2010

    Directory of Open Access Journals (Sweden)

    Luis N. Lanteri

    2012-12-01

    Full Text Available In recent years, there has been an extraordinary increase in international commodity prices, such as fossil fuels (oil and agricultural products. This paper analyzes the behavior of real prices of major agricultural commodities (wheat, corn, soybeans and rice using SVAR models, with short-term restrictions, and annual data covering the period 1960-2010. The results suggest that the prices of these commodities increase with improvements in industrial growth, easy monetary policy, dollar depreciation, and inventory reductions. There is an inverse relation between the ratios inventories/consumption and the real prices of grains.

  5. Psychophysiological Assessment in Pilots Performing Challenging Simulated and Real Flight Maneuvers.

    Science.gov (United States)

    Johannes, Bernd; Rothe, Stefanie; Gens, André; Westphal, Soeren; Birkenfeld, Katja; Mulder, Edwin; Rittweger, Jörn; Ledderhos, Carla

    2017-09-01

    The objective assessment of psychophysiological arousal during challenging flight maneuvers is of great interest to aerospace medicine, but remains a challenging task. In the study presented here, a vector-methodological approach was used which integrates different psychophysiological variables, yielding an integral arousal index called the Psychophysiological Arousal Value (PAV). The arousal levels of 15 male pilots were assessed during predetermined, well-defined flight maneuvers performed under simulated and real flight conditions. The physiological data, as expected, revealed inter- and intra-individual differences for the various measurement conditions. As indicated by the PAV, air-to-air refueling (AAR) turned out to be the most challenging task. In general, arousal levels were comparable between simulator and real flight conditions. However, a distinct difference was observed when the pilots were divided by instructors into two groups based on their proficiency in AAR with AWACS (AAR-Novices vs. AAR-Professionals). AAR-Novices had on average more than 2000 flight hours on other aircrafts. They showed higher arousal reactions to AAR in real flight (contact: PAV score 8.4 ± 0.37) than under simulator conditions (7.1 ± 0.30), whereas AAR-Professionals did not (8.5 ± 0.46 vs. 8.8 ± 0.80). The psychophysiological arousal value assessment was tested in field measurements, yielding quantifiable arousal differences between proficiency groups of pilots during simulated and real flight conditions. The method used in this study allows an evaluation of the psychophysiological cost during a certain flying performance and thus is possibly a valuable tool for objectively evaluating the actual skill status of pilots.Johannes B, Rothe S, Gens A, Westphal S, Birkenfeld K, Mulder E, Rittweger J, Ledderhos C. Psychophysiological assessment in pilots performing challenging simulated and real flight maneuvers. Aerosp Med Hum Perform. 2017; 88(9):834-840.

  6. Final environmental assessment: TRU waste drum staging building, Technical Area 55, Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    1996-01-01

    Much of the US Department of Energy's (DOE's) research on plutonium metallurgy and plutonium processing is performed at Los Alamos National Laboratory (LANL), in Los Alamos, New Mexico. LANL's main facility for plutonium research is the Plutonium Facility, also referred to as Technical Area 55 (TA-55). The main laboratory building for plutonium work within the Plutonium Facility (TA-55) is the Plutonium Facility Building 4, or PF-4. This Environmental Assessment (EA) analyzes the potential environmental effects that would be expected to occur if DOE were to stage sealed containers of transuranic (TRU) and TRU mixed waste in a support building at the Plutonium Facility (TA-55) that is adjacent to PF-4. At present, the waste containers are staged in the basement of PF-4. The proposed project is to convert an existing support structure (Building 185), a prefabricated metal building on a concrete foundation, and operate it as a temporary staging facility for sealed containers of solid TRU and TRU mixed waste. The TRU and TRU mixed wastes would be contained in sealed 55-gallon drums and standard waste boxes as they await approval to be transported to TA-54. The containers would then be transported to a longer term TRU waste storage area at TA-54. The TRU wastes are generated from plutonium operations carried out in PF-4. The drum staging building would also be used to store and prepare for use new, empty TRU waste containers

  7. Safety Culture Monitoring: How to Assess Safety Culture in Real Time?

    International Nuclear Information System (INIS)

    Zronek, B.; Maryska, J.; Treslova, L.

    2016-01-01

    Do you know what is current level of safety culture in your company? Are you able to follow trend changes? Do you know what your recent issues are? Since safety culture is understood as vital part of nuclear industry daily life, it is crucial to know what the current level is. It is common to perform safety culture survey or ad hoc assessment. This contribution shares Temelin NPP, CEZ approach how to assess safety culture level permanently. Using behavioral related outputs of gap solving system, observation program, dedicated surveys, regulatory assessment, etc., allows creating real time safety culture monitoring without the need to perform any other activities. (author)

  8. Garantías de los derechos reales mediante el sistema de registro y de seguro de título

    Directory of Open Access Journals (Sweden)

    Norma Loureiro Russo

    2014-11-01

    Full Text Available El concepto de seguridad jurídica tiene tal amplitud que trasciende cualquier funciónjurídica, ubicándose en la aplicacíón del derecho todo.Cabe destacar en ese concepto, sus valores esenciales y constitutivos, tales como la justicia y la seguridad, siendo la certeza uno de sus ingredientes. (...Contenido: Seguridad jurídica. Función notarial y seguridad jurídica. La publicidad registral y la seguridad jurídica. Esencia. Materia. Fines. Oponibilidad. Legitimidad.Garantía de los derechos reales y seguro de títulos. Origen del contrato de seguro de título. Concepto. Conclusiones

  9. Plan de comercialización para el posicionamiento de los productos apícolas (miel de abeja, jalea real y turrón) elaborados por la asociación de apicultores de la parroquia cacha “apica” en los supermercados mayoristas de la ciudad de Riobamba.

    OpenAIRE

    Chérrez Pazmiño, Ángel Yobani

    2015-01-01

    El objetivo del presente estudio fue elaborar un Plan de Comercialización para el Posicionamiento de los productos apícolas (Miel de abeja, Jalea real y Turrón) elaborados por la Asociación de productores apícolas “APICA” en los supermercados de la ciudad de Riobamba, con la finalidad que la empresa incremente el índice de sus ventas y estas generen mayores recursos económicos a los socios. Se realizó el estudio de mercado para determinar las preferencias de consumo de los productos apícolas...

  10. EGRESADOS DEL REAL COLEGIO DE MINERÍA EN LOS INICIOS DE LA REVOLUCIÓN DE INDEPENDENCIA DE MÉXICO. 1810. EGRESADOS DEL REAL COLEGIO DE MINERÍA EN LOS INICIOS DE LA REVOLUCIÓN DE INDEPENDENCIA DE MÉXICO. 1810.

    Directory of Open Access Journals (Sweden)

    Isauro Rionda Arreguín

    2012-02-01

    Full Text Available The Real Colegio de Mineria or Real Seminario de Mineria or Colegio Metalico was founded in 1792 and in january the 1st of that year admitted the first students. Several of their graduates during the firs decade of the XIX century worked in the mining industry in Guanajuato and were involved in the insurrection movement, among them were: José Antonio Rojas, Casimiro Chowell, Rafael Dávalos, y Ramón Fabié y Mariano Jiménez.Se funda en 1792 el Real Colegio de Minería o Real Seminario de Minería, o Colegio Metálico; institución que abre sus puertas a los primeros alumnos, el día primero de enero de ese año. Esos egresados del Real Colegio de Minería que en la primera década del siglo XIX trabajaron en la minería guanajuatense fueron: José Antonio Rojas, Casimiro Chowell, Rafael Dávalos, y Ramón Fabié y Mariano Jiménez.

  11. Validation and Assessment of Multi-GNSS Real-Time Precise Point Positioning in Simulated Kinematic Mode Using IGS Real-Time Service

    Directory of Open Access Journals (Sweden)

    Liang Wang

    2018-02-01

    Full Text Available Precise Point Positioning (PPP is a popular technology for precise applications based on the Global Navigation Satellite System (GNSS. Multi-GNSS combined PPP has become a hot topic in recent years with the development of multiple GNSSs. Meanwhile, with the operation of the real-time service (RTS of the International GNSS Service (IGS agency that provides satellite orbit and clock corrections to broadcast ephemeris, it is possible to obtain the real-time precise products of satellite orbits and clocks and to conduct real-time PPP. In this contribution, the real-time multi-GNSS orbit and clock corrections of the CLK93 product are applied for real-time multi-GNSS PPP processing, and its orbit and clock qualities are investigated, first with a seven-day experiment by comparing them with the final multi-GNSS precise product ‘GBM’ from GFZ. Then, an experiment involving real-time PPP processing for three stations in the Multi-GNSS Experiment (MGEX network with a testing period of two weeks is conducted in order to evaluate the convergence performance of real-time PPP in a simulated kinematic mode. The experimental result shows that real-time PPP can achieve a convergence performance of less than 15 min for an accuracy level of 20 cm. Finally, the real-time data streams from 12 globally distributed IGS/MGEX stations for one month are used to assess and validate the positioning accuracy of real-time multi-GNSS PPP. The results show that the simulated kinematic positioning accuracy achieved by real-time PPP on different stations is about 3.0 to 4.0 cm for the horizontal direction and 5.0 to 7.0 cm for the three-dimensional (3D direction.

  12. Acerca de las relaciones entre arqueología, patrimonio arqueológico y archivos : estudio del caso madrileño a través de los fondos documentales conservados en la Real Academia de la Historia

    OpenAIRE

    Salas Álvarez, Jesús

    2015-01-01

    Análisis de la relación existente entre la Arqueología y el Patrimonio Arqueológico, con la documentación conservada en los archivos y bibliotecas de las principales instituciones culturales españolas. A modo de ejemplo, el trabajo se centra en los fondos documentales que sobre arqueología madrileña se conservan en la Real Academia de la Historia.

  13. A real-time assessment of measurement uncertainty in the experimental characterization of sprays

    International Nuclear Information System (INIS)

    Panão, M R O; Moreira, A L N

    2008-01-01

    This work addresses the estimation of the measurement uncertainty of discrete probability distributions used in the characterization of sprays. A real-time assessment of this measurement uncertainty is further investigated, particularly concerning the informative quality of the measured distribution and the influence of acquiring additional information on the knowledge retrieved from statistical analysis. The informative quality is associated with the entropy concept as understood in information theory (Shannon entropy), normalized by the entropy of the most informative experiment. A new empirical correlation is derived between the error accuracy of a discrete cumulative probability distribution and the normalized Shannon entropy. The results include case studies using: (i) spray impingement measurements to study the applicability of the real-time assessment of measurement uncertainty, and (ii) the simulation of discrete probability distributions of unknown shape or function to test the applicability of the new correlation

  14. A generalised Dynamic Overflow Risk Assessment (DORA) for Real Time Control of urban drainage systems

    DEFF Research Database (Denmark)

    Vezzaro, Luca; Grum, Morten

    2014-01-01

    An innovative and generalised approach to the integrated Real Time Control of urban drainage systems is presented. The Dynamic Overflow Risk Assessment (DORA) strategy aims to minimise the expected Combined Sewer Overflow (CSO) risk by considering (i) the water volume presently stored in the drai......An innovative and generalised approach to the integrated Real Time Control of urban drainage systems is presented. The Dynamic Overflow Risk Assessment (DORA) strategy aims to minimise the expected Combined Sewer Overflow (CSO) risk by considering (i) the water volume presently stored...... and their uncertainty contributed to further improving the performance of drainage systems. The results of this paper will contribute to the wider usage of global RTC methods in the management of urban drainage networks....

  15. FTA real-time transit information assessment : white paper on literature review of real-time transit information systems.

    Science.gov (United States)

    Real-time transit information systems are key technology applications within the transit industry designed to provide better customer service by disseminating timely and accurate information. Riders use this information to make various decisions abou...

  16. Una ciudad de los vascones en el yacimiento de Campo Real/Fillera (Sos del Rey Católico-Sangüesa

    Directory of Open Access Journals (Sweden)

    Andreu Pintado, Javier

    2008-12-01

    Full Text Available The following paper deals with the detailed and preliminary study of the archaeological site of Campo Real/Fillera (Sos del Rey Católico/Sangüesa, between today Zaragoza and Navarra provinces specially focusing in its Roman period. The paper exposes a review of the archeological and epigraphical material from the site, proposes an urban condition for it and raises some hypothesis on its identification with one of the cities that ancient sources tribued to Vascones.El presente trabajo aborda el estudio detallado y preliminar del yacimiento arqueológico de Campo Real/Fillera (Sos del Rey Católico/Sangüesa, en el límite entre las actuales provincias de Zaragoza y Navarra con especial atención a su etapa romana. Se procede a la revisión del material arqueológico y epigráfico procedente del lugar, se defiende la condición de enclave urbano del yacimiento y se plantea una hipótesis respecto de su identificación con las ciudades que las fuentes antiguas atribuyen a los Vascones.

  17. REAL-TIME ASSESSMENT OF MICROWAVE ABLATION EFFICACY BY NIR SPECTROSCOPIC TECHNIQUE

    Directory of Open Access Journals (Sweden)

    JINZHE ZHAO

    2014-01-01

    Full Text Available Microwave ablation (MWA status monitoring in real time plays a key role in assessment of therapeutic effectiveness. As a novel real-time assessment method, near infrared spectroscopy (NIRs was used to evaluate the ablation efficacy. MWA experiments were carried out on in vitro porcine livers. An optical measurement system for biological tissue is developed by our lab to monitor reduced scattering coefficient $(\\mu_{s}^{'}$ at 690 nm of the coagulation zones. It is noted that $\\mu_{s}^{'}$ of liver tissue, which increases as the liver tissue being ablated, is clearly related with the coagulation status. $\\mu_{s}^{'}$ of normal tissue and coagulated tissue is 3–5 and 17–19 cm-1, respectively. Continuous changes of $\\mu_{s}^{'}$ demonstrate that optical parameter can be used as an efficacy evaluation factor because it essentially indicates the degree of thermal damage. Compared with temperature, optical parameter is more sensitive and accurate, which is promising for real-time therapeutic efficacy assessment in MWA.

  18. Improved Thévenin equivalent methods for real-time voltage stability assessment

    DEFF Research Database (Denmark)

    Perez, Angel; Jóhannsson, Hjörtur; Østergaard, Jacob

    2016-01-01

    An improved Thévenin equivalent method for real-time voltage stability assessment that uses wide-area information from synchrophasors is proposed. The improvements are a better modeling of the limited synchronous generators, and a processing that anticipates the effect of field current limiters......, before the latter are activated. Several study cases using detailed dynamic simulations of the Nordic test system have been used to assess the performance of the proposed improvements. Their effectiveness is analyzed and, based on the results, their possible application in combination...

  19. Suitability of voltage stability study methods for real-time assessment

    DEFF Research Database (Denmark)

    Perez, Angel; Jóhannsson, Hjörtur; Vancraeyveld, Pieter

    2013-01-01

    This paper analyzes the suitability of existing methods for long-term voltage stability assessment for real-time operation. An overview of the relevant methods is followed with a comparison that takes into account the accuracy, computational efficiency and characteristics when used for security...... assessment. The results enable an evaluation of the run time of each method with respect to the number of inputs. Furthermore, the results assist in identifying which of the methods is most suitable for realtime operation in future power system with production based on fluctuating energy sources....

  20. Evaluation of HVDC interconnection models for considering its impact in real-time voltage stability assessment

    DEFF Research Database (Denmark)

    Perez, Angel; Jóhannsson, Hjörtur; Lund, P.

    2015-01-01

    An approach to evaluate the HVDC interconnectionsmodels to be used in real-time voltage stability assessment is proposed.The existing models for the HVDC interconnections, thatare based on voltage source converter, were studied selecting theones that are suitable for its application in Thevenin...... equivalent ´methods for voltage stability assessment. The proposed methodis to evaluate the validity of the models by using synthetizedPMU measurements from simulations and from PMUs connectedto the danish system. Wide-area measurements are used toestimate the HVDC model parameters which are needed...

  1. Self-Motion Perception: Assessment by Real-Time Computer Generated Animations

    Science.gov (United States)

    Parker, Donald E.

    1999-01-01

    Our overall goal is to develop materials and procedures for assessing vestibular contributions to spatial cognition. The specific objective of the research described in this paper is to evaluate computer-generated animations as potential tools for studying self-orientation and self-motion perception. Specific questions addressed in this study included the following. First, does a non- verbal perceptual reporting procedure using real-time animations improve assessment of spatial orientation? Are reports reliable? Second, do reports confirm expectations based on stimuli to vestibular apparatus? Third, can reliable reports be obtained when self-motion description vocabulary training is omitted?

  2. Environmental assessment of remedial action, acid/middle Pueblo Canyon, Los Alamos, New Mexico

    International Nuclear Information System (INIS)

    1982-08-01

    The radiological survey of the former radioactive waste treatment plant site (TA-45), Acid Canyon, and Pueblo Canyon found residual radioactivity at the site itself and in the channel and banks of Acid, Pueblo, and lower Los Alamos Canyons, all the way to the Rio Grande. The largest reservoir of radioactive material is in lower Pueblo Canyon, which is on DOE property. The only areas where residual radioactivity exceeds the proposed cleanup criteria are at the former vehicle decontamination facility, located between the former treatment plant site and Acid Canyon, around the former untreated waste outfall and for a short distance below, and in two small areas farther down in Acid Canyon. The three alternatives proposed are (1) to take no action, (2) to fence the areas where the residual radioactivity exceeds the proposed criteria (minimal action), and (3) to clean up the former vehicle decontamination facility and around the former untreated waste outfall. Calculations based on actual measurements indicate that the annual dose at the location having the greatest residual radioactivity would be about 12% of the applicable guideline. Most doses are much smaller than that. No environmental impacts are associated with either the no-action or minimal action alternatives. The impact associated with the cleanup alternative is very small. The preferred alternative is to clean up the areas around the former vehicle decontamination facility and the untreated waste outfall. This course of action is recommended not because of any real danger associated with the residual radioactivity, but rather because the cleanup operation is a minor effort and would conform with the ALARA (as low as reasonably achievable) philosophy

  3. Transferability and robustness of real-time freeway crash risk assessment.

    Science.gov (United States)

    Shew, Cameron; Pande, Anurag; Nuworsoo, Cornelius

    2013-09-01

    This study examines the data from single loop detectors on northbound (NB) US-101 in San Jose, California to estimate real-time crash risk assessment models. The classification tree and neural network based crash risk assessment models developed with data from NB US-101 are applied to data from the same freeway, as well as to the data from nearby segments of the SB US-101, NB I-880, and SB I-880 corridors. The performance of crash risk assessment models on these nearby segments is the focus of this research. The model applications show that it is in fact possible to use the same model for multiple freeways, as the underlying relationships between traffic data and crash risk remain similar. The framework provided here may be helpful to authorities for freeway segments with newly installed traffic surveillance apparatuses, since the real-time crash risk assessment models from nearby freeways with existing infrastructure would be able to provide a reasonable estimate of crash risk. The robustness of the model output is also assessed by location, time of day, and day of week. The analysis shows that on some locations the models may require further learning due to higher than expected false positive (e.g., the I-680/I-280 interchange on US-101 NB) or false negative rates. The approach for post-processing the results from the model provides ideas to refine the model prior to or during the implementation. Copyright © 2013 National Safety Council and Elsevier Ltd. All rights reserved.

  4. Condition assessment of the Los Alamos National Laboratory radioactive liquid waste collection system

    International Nuclear Information System (INIS)

    Edgemon, G.L.; Moss, W.D.; Worland, V.P.

    2004-01-01

    The radioactive liquid waste collection system (RLWCS) at Los Alamos National Laboratory (LANE) is a site-wide double-encased piping system installed in 1982 that allows radioactive liquid waste (RLW) producing facilities to gravity drain their waste to the radioactive liquid waste treatment facility (RLWTF) through a system of underground high-density polyethylene (HDPE) pipes and vaults. The RLWCS stretches approximately four miles and typically receives approximately 10,000 gallons of RLW per day for treatment at the RLWTF. Uncertainty of the current condition of the RLWCS was recently identified as a potential risk to the future continued availability of the RLW treatment function. A condition assessment was performed in April 2004 to evaluate the risks and estimate the remaining useful life of the existing RLWCS. Several representative and 'worst-case' RLWCS primary piping sections and their associated inspection vaults were selected for direct visual assessment, remote borescopic examination, and in-situ durometer testing. This field investigation combined with an RLWCS materials compatibility review showed that the primary piping of the RLWCS is in relatively good condition, with only a few noteworthy areas of degradation.

  5. Wide-Area Assessment of Aperiodic Small Signal Rotor Angle Stability in Real-Time

    DEFF Research Database (Denmark)

    Jóhannsson, Hjörtur; Nielsen, Arne Hejde; Østergaard, Jacob

    2013-01-01

    This paper presents the details of a new real-time stability assessment method. The method assesses a particular mechanism of stability: each generator’s capability to generate sufficient steady state electromechanical torque. The lack of sufficient steady state torque causes aperiodic increase...... of multiple operating points is derived in the paper. Finally, results from time-domain simulation of instability scenarios in the Nordic32 test system are presented and results used for testing the assessment method. The results illustrate the method’s capability to efficiently identify the location...... in rotor angle and a loss of synchronism, referred to as aperiodic small signal instability. The paper provides the theoretical background of the method and an analytical assessment criterion. Furthermore, a mathematical mapping of the generators’ operating points that enables informative visualization...

  6. An accelerometry-based methodology for assessment of real-world bilateral upper extremity activity.

    Directory of Open Access Journals (Sweden)

    Ryan R Bailey

    Full Text Available The use of both upper extremities (UE is necessary for the completion of many everyday tasks. Few clinical assessments measure the abilities of the UEs to work together; rather, they assess unilateral function and compare it between affected and unaffected UEs. Furthermore, clinical assessments are unable to measure function that occurs in the real-world, outside the clinic. This study examines the validity of an innovative approach to assess real-world bilateral UE activity using accelerometry.Seventy-four neurologically intact adults completed ten tasks (donning/doffing shoes, grooming, stacking boxes, cutting playdough, folding towels, writing, unilateral sorting, bilateral sorting, unilateral typing, and bilateral typing while wearing accelerometers on both wrists. Two variables, the Bilateral Magnitude and Magnitude Ratio, were derived from accelerometry data to distinguish between high- and low-intensity tasks, and between bilateral and unilateral tasks. Estimated energy expenditure and time spent in simultaneous UE activity for each task were also calculated.The Bilateral Magnitude distinguished between high- and low-intensity tasks, and the Magnitude Ratio distinguished between unilateral and bilateral UE tasks. The Bilateral Magnitude was strongly correlated with estimated energy expenditure (ρ = 0.74, p<0.02, and the Magnitude Ratio was strongly correlated with time spent in simultaneous UE activity (ρ = 0.93, p<0.01 across tasks.These results demonstrate face validity and construct validity of this methodology to quantify bilateral UE activity during the performance of everyday tasks performed in a laboratory setting, and can now be used to assess bilateral UE activity in real-world environments.

  7. Assessing facade value - how clients make business cases in changing real estate markets

    Directory of Open Access Journals (Sweden)

    Alexandra den Heijer

    2013-12-01

    Full Text Available Relevance: The value of any intervention in the built environment is most relevant for the stakeholders that are investing in it. For them all costs need to be balanced with benefits - not necessarily directly financial, but adding value to the performance of the accommodated organization. Business cases contain performance criteria like competitive advantage (branding the organization, productivity (optimally supporting users of the building, profitability (on organizational level and sustainable development (monitoring the ecological footprint. In the changing real estate markets – from supply-driven to demand-driven and with increasingly higher vacancy rates – priorities in decisions about buildings have been shifting.Purpose: This paper elaborates on how (a the trends in real estate markets and (b changing priorities in decision making affect the quality demand for buildings and their facades.Design/methodology/approach: This paper is based on research of the Real Estate Management chair in general (market analysis, transformation trends, conceptual frameworks and more specifically on decisions about university campuses in the past 10 years (14 campuses and 57 buildings assessed.Findings: This paper provides both conceptual frameworks to assess the (added value of interventions in the built environment for the client and their (changing priorities in the brief for buildings and their facades.

  8. Self-motion perception: assessment by real-time computer-generated animations

    Science.gov (United States)

    Parker, D. E.; Phillips, J. O.

    2001-01-01

    We report a new procedure for assessing complex self-motion perception. In three experiments, subjects manipulated a 6 degree-of-freedom magnetic-field tracker which controlled the motion of a virtual avatar so that its motion corresponded to the subjects' perceived self-motion. The real-time animation created by this procedure was stored using a virtual video recorder for subsequent analysis. Combined real and illusory self-motion and vestibulo-ocular reflex eye movements were evoked by cross-coupled angular accelerations produced by roll and pitch head movements during passive yaw rotation in a chair. Contrary to previous reports, illusory self-motion did not correspond to expectations based on semicircular canal stimulation. Illusory pitch head-motion directions were as predicted for only 37% of trials; whereas, slow-phase eye movements were in the predicted direction for 98% of the trials. The real-time computer-generated animations procedure permits use of naive, untrained subjects who lack a vocabulary for reporting motion perception and is applicable to basic self-motion perception studies, evaluation of motion simulators, assessment of balance disorders and so on.

  9. Assessing the Value of Real-life Brands in Virtual Worlds

    DEFF Research Database (Denmark)

    Mattsson, Jan; Barnes, Stuart; Hartley, Nicole

    2015-01-01

    World. A key finding is the difficulty in creating emotional brand value in Second Life which has serious implications for the sustainability of current real-life brands in Virtual Worlds. The paper rounds off with conclusions and implications for future research and practice in this very new area.......Virtual Worlds are a significant new market environment for brand-building through experiential customer service interactions. Using value theory, this paper aims to assess the experiential brand value of real-life brands that have moved to the Virtual World of Second Life. A key premise...... is that current brand offerings in Virtual Worlds do not offer consumers adequate experiential value. The results demonstrate both the validity of an axiological approach to examining brand value, and highlight significant problems in consumer perceptions of the experiential value of brands within the Virtual...

  10. Assessing facade value - how clients make business cases in changing real estate markets

    Directory of Open Access Journals (Sweden)

    Alexandra Den Heijer

    2013-12-01

    Full Text Available Corresponding author: Dr. ir. Alexandra den Heijer, Delft University of Technology (TU Delft, Faculty of Architecture and the Built Environment, Department of Real Estate & Housing, Julianalaan 134, 2628 BL Delft, The Netherlands. Tel.: +31 15 278 4159; E-mail: a.c.denheijer@tudelft.nl RELEVANCE: The value of any intervention in the built environment is most relevant for the stakeholders that are investing in it. For them all costs need to be balanced with benefits - not necessarily directly financial, but adding value to the performance of the accommodated organization. Business cases contain performance criteria like competitive advantage (branding the organization, productivity (optimally supporting users of the building, profitability (on organizational level and sustainable development (monitoring the ecological footprint. In the changing real estate markets – from supply-driven to demand-driven and with increasingly higher vacancy rates – priorities in decisions about buildings have been shifting. PURPOSE: This paper elaborates on how (a the trends in real estate markets and (b changing priorities in decision making affect the quality demand for buildings and their facades. DESIGN/METHODOLOGY/APPROACH: This paper is based on research of the Real Estate Management chair in general (market analysis, transformation trends, conceptual frameworks and more specifically on decisions about university campuses in the past 10 years (14 campuses and 57 buildings assessed. FINDINGS: This paper provides both conceptual frameworks to assess the (added value of interventions in the built environment for the client and their (changing priorities in the brief for buildings and their facades

  11. Los capítulos primero y segundo del libro I de la Primera parte de los Comentarios Reales del Inca Garcilaso a la luz de la retórica grecolatina

    Directory of Open Access Journals (Sweden)

    Violeta Pérez Custodio

    2013-10-01

    Full Text Available This paper aims to offer an example of the influence of ancient rhetoric in the first and second chapters of the first book of the Primera parte de los Comentarios reales by the Inca Garcilaso, where the author deals with several cosmographic and geographic topics under controversy, as it is usual in other chronicles of the Indies. In order to do it, the argumentative structure of these chapters is compared to the argumentative strategies contained in the thesis, the progymnasma used from the Antiquity to practice how to amplify a matter of debate. One of the variations of the thesis was the “theoretical thesis”, dealing with cosmographic issues closely related to the ones discussed by Garcilaso. The similarity between the argumentative strategies recommended in the thesis and the ones used in the two chapters analysed here suggest that the Inca took advantage of the resources provided by this training exercise. It also reinforces the idea that the Peruvian historian mastered the rhetorical technique, although he didn't received any academic education.

  12. Los capítulos primero y segundo del libro I de la Primera parte de los Comentarios Reales del Inca Garcilaso a la luz de la retórica grecolatina

    Directory of Open Access Journals (Sweden)

    Pérez Custodio, Violeta

    2013-10-01

    Full Text Available This paper aims to offer an example of the influence of ancient rhetoric in the first and second chapters of the first book of the Primera parte de los Comentarios reales by the Inca Garcilaso, where the author deals with several cosmographic and geographic topics under controversy, as it is usual in other chronicles of the Indies. In order to do it, the argumentative structure of these chapters is compared to the argumentative strategies contained in the thesis, the progymnasma used from the Antiquity to practice how to amplify a matter of debate. One of the variations of the thesis was the “theoretical thesis”, dealing with cosmographic issues closely related to the ones discussed by Garcilaso. The similarity between the argumentative strategies recommended in the thesis and the ones used in the two chapters analysed here suggest that the Inca took advantage of the resources provided by this training exercise. It also reinforces the idea that the Peruvian historian mastered the rhetorical technique, although he didn't received any academic education

  13. Imaging techniques used for the real-time assessment of angiogenesis in digestive cancers

    DEFF Research Database (Denmark)

    Saftoiu, Adrian; Vilmann, Peter; Săftoiu, Adrian

    2011-01-01

    Angiogenesis has a critical role in primary tumor growth and the development of metastases. Several angiogenesis inhibitors were recently developed, being a very attractive target for digestive tumor therapy. However, individualized therapy should not only be based on the pre-treatment imaging...... of reviews was to analyze and enhance current knowledge and future perspectives about the real-time assessment of angiogenesis in digestive cancers, used for the longitudinal monitoring of the effects of chemo-radiotherapy (including anti-angiogenic therapies), as well as for the precise targeting of drugs...

  14. An assessment of the real-time application capabilities of the SIFT computer system

    Science.gov (United States)

    Butler, R. W.

    1982-01-01

    The real-time capabilities of the SIFT computer system, a highly reliable multicomputer architecture developed to support the flight controls of a relaxed static stability aircraft, are discussed. The SIFT computer system was designed to meet extremely high reliability requirements and to facilitate a formal proof of its correctness. Although SIFT represents a significant achievement in fault-tolerant system research it presents an unusual and restrictive interface to its users. The characteristics of the user interface and its impact on application system design are assessed.

  15. Can virtual reality exposure therapy gains be generalized to real life? A meta-analysis of studies applying behavioral assessments

    NARCIS (Netherlands)

    Morina, N.; Ijntema, H.; Meyerbröker, K.; Emmelkamp, P.M.G.

    2015-01-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials

  16. Assessment of Predictor Importance with the Example of the Real Estate Market

    Directory of Open Access Journals (Sweden)

    Kubus Mariusz

    2016-12-01

    Full Text Available Regression methods can be used for the valuation of real estate in the comparative approach. However, one of the problems of predictive modelling is the presence of redundant or irrelevant variables in data. Such variables can decrease the stability of models, and they can even reduce prediction accuracy. The choice of real estate’s features is largely determined by an appraiser, who is guided by his/her experience. Still, the use of statistical methods of a feature selection can lead to a more accurate valuation model. In the paper we apply regularized linear regression which belongs to embedded methods of a feature selection. For the considered data set of real estate land designated for single-family housing we obtained a model, which led to a more accurate valuation than some other popular linear models applied with or without a feature selection. To assess the model’s quality we used the leave-one-out cross-validation.

  17. Assessing Efficiency of Taxation of Banks and Enterprises of the Real Sector of Economy of Ukraine

    Directory of Open Access Journals (Sweden)

    Olkhovyk Volodymyr V.

    2013-12-01

    Full Text Available The article analysis the tax load for the banking system in general. Analysis showed the tax load of the banks is rather low and does not reach the fifth part of 1 percent. At the same time, by individual branches of the real sector of economy this indicator is in an average for 5 years 5 – 8 percent, which confirms violation of the principle of proportionality of the taxation system of Ukraine. The ratio of elasticity of taxes of the banks showed unevenness of distribution of taxes if compared with dynamics of change of GDP. However, taxes of the real sector are distributed in proportion to the change of the GDP share. Calculation of the Herfindahl index allowed assessment of efficiency of taxation of banks in the structure of the economy of Ukraine. The index of concentration of taxation of banks had a rather low value during the analysed period (2008 – 2012, which is confirmed by data on a low tax load of the banks if compared to rather high values of tax load at enterprises of the real sector of economy.

  18. Real time security assessment in national load dispatch centre, Tenaga Nasional Berhad, Malaysia

    Energy Technology Data Exchange (ETDEWEB)

    Sreedharan, G. [Tenaga Nasional Berhad, Kuala Lumpur (Malaysia); Moghavvemi, M. [Univ. of Malaya, Kuala Lumpur (Malaysia)

    2007-07-01

    Electric energy is one of the most important resources of modern industrial society. Electric power is available to the user instantly at the correct voltage, frequency and exactly at the amount that is needed. However, the power system is subjected to constant disturbances created by random load changes, faults created by natural causes and by equipment failures. One of the major impacts of the disturbances to the system is the impact imposed on transmission networks or corridors, which have increased the demand for more accurate and up to date information on the power system. It has become impossible to operate the system with an acceptable degree of security by using traditional operational planning studies that are conducted off-line and use forecast conditions to predict system security limits. Therefore the use of on-line security assessment is quickly becoming a necessity. This paper simplified the general off-line security assessment methodology by attempting to use the real time system snap shot data as an input to the dynamic security assessment tool namely VSAT. The study used raw data produced at every 10 minute cycle in order to conduct a security assessment of the power system, including current power system load; network topology; unit commitment; and generator and transmission line outages. The purpose of the project was to implement a real time security assessment to benefit the system operators to assist them in their daily work in monitoring and operating the power system in Tenaga Nasional Berhad. The paper discussed project implementation including a description of the project and project background. It discussed the operation of VSAT, result display, and future enhancement. 18 refs., 5 figs.

  19. Assessment of Multiple GNSS Real-Time SSR Products from Different Analysis Centers

    Directory of Open Access Journals (Sweden)

    Zhiyu Wang

    2018-03-01

    Full Text Available The real-time State Space Representation (SSR product of the GNSS (Global Navigation Satellite System orbit and clock is one of the most essential corrections for real-time precise point positioning (PPP. In this work, the performance of current SSR products from eight analysis centers were assessed by comparing it with the final product and the accuracy of real-time PPP. Numerical results showed that (1 the accuracies of the GPS SSR product were better than 8 cm for the satellite orbit and 0.3 ns for the satellite clock; (2 the accuracies of the GLONASS (GLObalnaya NAvigatsionnaya Sputnikovaya Sistema SSR product were better than 10 cm for orbit RMS (Root Mean Square and 0.6 ns for clock STD (Standard Deviation; and (3 the accuracies of the BDS (BeiDou Navigation Satellite System and Galileo SSR products from CLK93 were about 14.54 and 4.42 cm for the orbit RMS and 0.32 and 0.18 ns for the clock STD, respectively. The simulated kinematic PPP results obtained using the SSR products from CLK93 and CLK51 performed better than those using other SSR products; and the accuracy of PPP based on all products was better than 6 and 10 cm in the horizontal and vertical directions, respectively. The real-time kinematic PPP experiment carried out in Beijing, Tianjin, and Shijiazhuang, China indicated that the SSR product CLK93 from Centre National d’Etudes Spatiales (CNES had a better performance than CAS01. Moreover, the PPP with GPS + BDS dual systems had a higher accuracy than those with only a GPS single system.

  20. La materia económica en «La Florida del Inca» y los «Comentarios reales»: testimonio colonial y discurso historiográfico

    Directory of Open Access Journals (Sweden)

    Julián Díez Torres

    2018-01-01

    Full Text Available Si bien el Inca Garcilaso de la Vega no escribió tratados sino obras de historia política, las referencias económicas en La Florida del Inca (1605 y las dos partes de los Comentarios reales (1609, 1617 ofrecen un testimonio indirecto de algunos de los procesos económicos del colonialismo temprano. Este artículo sintetiza las menciones de Garcilaso al comercio, los precios y los bienes materiales, y las sitúa dentro de la evolución de su manera de escribir historia y dentro de sus opiniones sobre la historia del Nuevo Mundo (incluyendo tanto interpretaciones de procesos históricos como recuerdos personales.

  1. An accuracy assessment of realtime GNSS time series toward semi- real time seafloor geodetic observation

    Science.gov (United States)

    Osada, Y.; Ohta, Y.; Demachi, T.; Kido, M.; Fujimoto, H.; Azuma, R.; Hino, R.

    2013-12-01

    Large interplate earthquake repeatedly occurred in Japan Trench. Recently, the detail crustal deformation revealed by the nation-wide inland GPS network called as GEONET by GSI. However, the maximum displacement region for interplate earthquake is mainly located offshore region. GPS/Acoustic seafloor geodetic observation (hereafter GPS/A) is quite important and useful for understanding of shallower part of the interplate coupling between subducting and overriding plates. We typically conduct GPS/A in specific ocean area based on repeated campaign style using research vessel or buoy. Therefore, we cannot monitor the temporal variation of seafloor crustal deformation in real time. The one of technical issue on real time observation is kinematic GPS analysis because kinematic GPS analysis based on reference and rover data. If the precise kinematic GPS analysis will be possible in the offshore region, it should be promising method for real time GPS/A with USV (Unmanned Surface Vehicle) and a moored buoy. We assessed stability, precision and accuracy of StarFireTM global satellites based augmentation system. We primarily tested for StarFire in the static condition. In order to assess coordinate precision and accuracy, we compared 1Hz StarFire time series and post-processed precise point positioning (PPP) 1Hz time series by GIPSY-OASIS II processing software Ver. 6.1.2 with three difference product types (ultra-rapid, rapid, and final orbits). We also used difference interval clock information (30 and 300 seconds) for the post-processed PPP processing. The standard deviation of real time StarFire time series is less than 30 mm (horizontal components) and 60 mm (vertical component) based on 1 month continuous processing. We also assessed noise spectrum of the estimated time series by StarFire and post-processed GIPSY PPP results. We found that the noise spectrum of StarFire time series is similar pattern with GIPSY-OASIS II processing result based on JPL rapid orbit

  2. Automating Flood Hazard Mapping Methods for Near Real-time Storm Surge Inundation and Vulnerability Assessment

    Science.gov (United States)

    Weigel, A. M.; Griffin, R.; Gallagher, D.

    2015-12-01

    Storm surge has enough destructive power to damage buildings and infrastructure, erode beaches, and threaten human life across large geographic areas, hence posing the greatest threat of all the hurricane hazards. The United States Gulf of Mexico has proven vulnerable to hurricanes as it has been hit by some of the most destructive hurricanes on record. With projected rises in sea level and increases in hurricane activity, there is a need to better understand the associated risks for disaster mitigation, preparedness, and response. GIS has become a critical tool in enhancing disaster planning, risk assessment, and emergency response by communicating spatial information through a multi-layer approach. However, there is a need for a near real-time method of identifying areas with a high risk of being impacted by storm surge. Research was conducted alongside Baron, a private industry weather enterprise, to facilitate automated modeling and visualization of storm surge inundation and vulnerability on a near real-time basis. This research successfully automated current flood hazard mapping techniques using a GIS framework written in a Python programming environment, and displayed resulting data through an Application Program Interface (API). Data used for this methodology included high resolution topography, NOAA Probabilistic Surge model outputs parsed from Rich Site Summary (RSS) feeds, and the NOAA Census tract level Social Vulnerability Index (SoVI). The development process required extensive data processing and management to provide high resolution visualizations of potential flooding and population vulnerability in a timely manner. The accuracy of the developed methodology was assessed using Hurricane Isaac as a case study, which through a USGS and NOAA partnership, contained ample data for statistical analysis. This research successfully created a fully automated, near real-time method for mapping high resolution storm surge inundation and vulnerability for the

  3. Use of NASA Near Real-Time and Archived Satellite Data to Support Disaster Assessment

    Science.gov (United States)

    McGrath, Kevin M.; Molthan, Andrew L.; Burks, Jason E.

    2014-01-01

    NASA's Short-term Prediction Research and Transition (SPoRT) Center partners with the NWS to provide near realtime data in support of a variety of weather applications, including disasters. SPoRT supports NASA's Applied Sciences Program: Disasters focus area by developing techniques that will aid the disaster monitoring, response, and assessment communities. SPoRT has explored a variety of techniques for utilizing archived and near real-time NASA satellite data. An increasing number of end-users - such as the NWS Damage Assessment Toolkit (DAT) - access geospatial data via a Web Mapping Service (WMS). SPoRT has begun developing open-standard Geographic Information Systems (GIS) data sets via WMS to respond to end-user needs.

  4. Loose and Tight GNSS/INS Integrations: Comparison of Performance Assessed in Real Urban Scenarios.

    Science.gov (United States)

    Falco, Gianluca; Pini, Marco; Marucco, Gianluca

    2017-01-29

    Global Navigation Satellite Systems (GNSSs) remain the principal mean of positioning in many applications and systems, but in several types of environment, the performance of standalone receivers is degraded. Although many works show the benefits of the integration between GNSS and Inertial Navigation Systems (INSs), tightly-coupled architectures are mainly implemented in professional devices and are based on high-grade Inertial Measurement Units (IMUs). This paper investigates the performance improvements enabled by the tight integration, using low-cost sensors and a mass-market GNSS receiver. Performance is assessed through a series of tests carried out in real urban scenarios and is compared against commercial modules, operating in standalone mode or featuring loosely-coupled integrations. The paper describes the developed tight-integration algorithms with a terse mathematical model and assesses their efficacy from a practical perspective.

  5. Critical Care Nurses Inadequately Assess SAPS II Scores of Very Ill Patients in Real Life

    Directory of Open Access Journals (Sweden)

    Andreas Perren

    2012-01-01

    Full Text Available Background. Reliable ICU severity scores have been achieved by various healthcare workers but nothing is known regarding the accuracy in real life of severity scores registered by untrained nurses. Methods. In this retrospective multicentre audit, three reviewers independently reassessed 120 SAPS II scores. Correlation and agreement of the sum-scores/variables among reviewers and between nurses and the reviewers’ gold standard were assessed globally and for tertiles. Bland and Altman (gold standard—nurses of sum scores and regression of the difference were determined. A logistic regression model identifying risk factors for erroneous assessments was calculated. Results. Correlation for sum scores among reviewers was almost perfect (mean ICC = 0.985. The mean (±SD nurse-registered SAPS II sum score was 40.3±20.2 versus 44.2±24.9 of the gold standard (32 points scores. The lowest agreement was found in high SAPS II tertiles for haemodynamics (k = 0.45–0.51. Conclusions. In real life, nurse-registered SAPS II scores of very ill patients are inaccurate. Accuracy of scores was not associated with nurses’ characteristics.

  6. Diffuse reflectance spectroscopy as a tool for real-time tissue assessment during colorectal cancer surgery

    Science.gov (United States)

    Baltussen, Elisabeth J. M.; Snaebjornsson, Petur; de Koning, Susan G. Brouwer; Sterenborg, Henricus J. C. M.; Aalbers, Arend G. J.; Kok, Niels; Beets, Geerard L.; Hendriks, Benno H. W.; Kuhlmann, Koert F. D.; Ruers, Theo J. M.

    2017-10-01

    Colorectal surgery is the standard treatment for patients with colorectal cancer. To overcome two of the main challenges, the circumferential resection margin and postoperative complications, real-time tissue assessment could be of great benefit during surgery. In this ex vivo study, diffuse reflectance spectroscopy (DRS) was used to differentiate tumor tissue from healthy surrounding tissues in patients with colorectal neoplasia. DRS spectra were obtained from tumor tissue, healthy colon, or rectal wall and fat tissue, for every patient. Data were randomly divided into training (80%) and test (20%) sets. After spectral band selection, the spectra were classified using a quadratic classifier and a linear support vector machine. Of the 38 included patients, 36 had colorectal cancer and 2 had an adenoma. When the classifiers were applied to the test set, colorectal cancer could be discriminated from healthy tissue with an overall accuracy of 0.95 (±0.03). This study demonstrates the possibility to separate colorectal cancer from healthy surrounding tissue by applying DRS. High classification accuracies were obtained both in homogeneous and inhomogeneous tissues. This is a fundamental step toward the development of a tool for real-time in vivo tissue assessment during colorectal surgery.

  7. Real-Time Risk Assessment Framework for Unmanned Aircraft System (UAS) Traffic Management (UTM)

    Science.gov (United States)

    Ancel, Ersin; Capristan, Francisco M.; Foster, John V.; Condotta, Ryan

    2017-01-01

    The new Federal Aviation Administration (FAA) Small Unmanned Aircraft rule (Part 107) marks the first national regulations for commercial operation of small unmanned aircraft systems (sUAS) under 55 pounds within the National Airspace System (NAS). Although sUAS flights may not be performed beyond visual line-of-sight or over non- participant structures and people, safety of sUAS operations must still be maintained and tracked at all times. Moreover, future safety-critical operation of sUAS (e.g., for package delivery) are already being conceived and tested. NASA's Unmanned Aircraft System Trac Management (UTM) concept aims to facilitate the safe use of low-altitude airspace for sUAS operations. This paper introduces the UTM Risk Assessment Framework (URAF) which was developed to provide real-time safety evaluation and tracking capability within the UTM concept. The URAF uses Bayesian Belief Networks (BBNs) to propagate off -nominal condition probabilities based on real-time component failure indicators. This information is then used to assess the risk to people on the ground by calculating the potential impact area and the effects of the impact. The visual representation of the expected area of impact and the nominal risk level can assist operators and controllers with dynamic trajectory planning and execution. The URAF was applied to a case study to illustrate the concept.

  8. Carded Tow Real-Time Color Assessment: A Spectral Camera-Based System

    Directory of Open Access Journals (Sweden)

    Rocco Furferi

    2016-08-01

    Full Text Available One of the most important parameters to be controlled during the production of textile yarns obtained by mixing pre-colored fibers, is the color correspondence between the manufactured yarn and a given reference, usually provided by a designer or a customer. Obtaining yarns from raw pre-colored fibers is a complex manufacturing process entailing a number of steps such as laboratory sampling, color recipe corrections, blowing, carding and spinning. Carding process is the one devoted to transform a “fuzzy mass” of tufted fibers into a regular mass of untwisted fibers, named “tow”. During this process, unfortunately, the correspondence between the color of the tow and the target one cannot be assured, thus leading to yarns whose color differs from the one used for reference. To solve this issue, the main aim of this work is to provide a system able to perform a spectral camera-based real-time measurement of a carded tow, to assess its color correspondence with a reference carded fabric and, at the same time, to monitor the overall quality of the tow during the carding process. Tested against a number of differently colored carded fabrics, the proposed system proved its effectiveness in reliably assessing color correspondence in real-time.

  9. Continuous Real-time Viability Assessment of Kidneys Based on Oxygen Consumption

    Science.gov (United States)

    Weegman, B.P.; Kirchner, V.A.; Scott, W.E.; Avgoustiniatos, E.S.; Suszynski, T.M.; Ferrer-Fabrega, J.; Rizzari, M.D.; Kidder, L.S.; Kandaswamy, R.; Sutherland, D.E.R.; Papas, K.K.

    2010-01-01

    Background Current ex vivo quality assessment of donor kidneys is limited to vascular resistance measurements and histological analysis. New techniques for the assessment of organ quality before transplantation may further improve clinical outcomes while expanding the depleted deceased-donor pool. We propose the measurement of whole organ oxygen consumption rate (WOOCR) as a method to assess the quality of kidneys in real time before transplantation. Methods Five porcine kidneys were procured using a donation after cardiac death (DCD) model. The renal artery and renal vein were cannulated and the kidney connected to a custom-made hypothermic machine perfusion (HMP) system equipped with an inline oxygenator and fiber-optic oxygen sensors. Kidneys were perfused at 8°C, and the perfusion parameters and partial oxygen pressures (pO2) were measured to calculate WOOCR. Results Without an inline oxygenator, the pO2 of the perfusion solution at the arterial inlet and venous outlet diminished to near 0 within minutes. However, once adequate oxygenation was provided, a significant pO2 difference was observed and used to calculate the WOOCR. The WOOCR was consistently measured from presumably healthy kidneys, and results suggest that it can be used to differentiate between healthy and purposely damaged organs. Conclusions Custom-made HMP systems equipped with an oxygenator and inline oxygen sensors can be applied for WOOCR measurements. We suggest that WOOCR is a promising approach for the real-time quality assessment of kidneys and other organs during preservation before transplantation. PMID:20692397

  10. LabVIEW aplicado al diagnóstico de estado en tiempo real de transformadores de potencia; LabVIEW apply to diagnostic that assess the condition in real time of the power transfor

    Directory of Open Access Journals (Sweden)

    Eliezer Fernández Padrón

    2014-04-01

    Full Text Available Este trabajo está dirigido al rediseño del Sistema de Adquisición y Procesamiento de Datos de la Estación para el Diagnóstico de Estado en Tiempo Real del Autotransformador de Potencia No. 2 de 100MVA, de la Subestación Barquisimeto de Venezuela, a partir de controladores embebidos en tiempo real de la familia cRIO de National Instruments y las técnicas de programación que ofrece la plataforma NI LabVIEW, con la finalidad de integrar un sistema único (software-hardware que permita aumentar la calidad en las mediciones, el procesamiento de los datos, la interface hombre-máquina, su capacidad de expansión y reproducibilidad. El mismo puede ser accedido mediante navegadores Web de Internet y transferir datos en tiempo real a través de la red, además es capaz de trabajar autónomo presentando respaldo en comunicación y alimentación de energía eléctrica, logrando un mejor servicio de diagnóstico continuo en dicho autotransformador.  This work is focused on the redesign of the Acquisition System and Processing Data of the Station for the Diagnostic that Assess the Condition in Real Time of the 100MVA Power Autotransformer No. 2 of the Substation Barquisimeto from Venezuela with the embedded controllers in real time of the cRIO technology of the National Instruments and the programming techniques supported by the NI LabVIEW platform with the purpose of integrating an unique system (hardware-software that allows to improve the quality in the measurements, the processing data, the man-machine interface, its expansion capability and reproduction. This system can be obtained by the internet web browser and it can transfer data in real time through the network, it is also able to work autonomous having a back in communicating and electrical energy feeding, getting a better continuous diagnostic service and the autotransformer.

  11. LabVIEW aplicado al diagnóstico de estado en tiempo real de transformadores de potencia LabVIEW apply to diagnostic that assess the condition in real time of the power transformers

    Directory of Open Access Journals (Sweden)

    Eliezer Fernández Padrón

    2012-02-01

    Full Text Available Este trabajo está dirigido al rediseño del Sistema de Adquisición y Procesamiento de Datos de la Estación para el Diagnóstico de Estado en Tiempo Real del Autotransformador de Potencia No. 2 de 100MVA, de la Subestación Barquisimeto de Venezuela, a partir de controladores embebidos en tiempo real de la familia cRIO de National Instruments y las técnicas de programación que ofrece la plataforma NI LabVIEW, con la finalidad de integrar un sistema único (software-hardware que permita aumentar la calidad en las mediciones, el procesamiento de los datos, la interface hombre-máquina, su capacidad de expansión y reproducibilidad. El mismo puede ser accedido mediante navegadores Web de Internet y transferir datos en tiempo real a través de la red, además es capaz de trabajar autónomo presentando respaldo en comunicación y alimentación de energía eléctrica, logrando un mejor servicio de diagnóstico continuo en dicho autotransformador.This work is focused on the redesign of the Acquisition System and Processing Data of the Station for the Diagnostic that Assess the Condition in Real Time of the 100MVA Power Autotransformer No. 2 of the Substation Barquisimeto from Venezuela with the embedded controllers in real time of the cRIO technology of the National Instruments and the programming techniques supported by the NI LabVIEW platform with the purpose of integrating an unique system (hardware-software that allows to improve the quality in the measurements, the processing data, the man-machine interface, its expansion capability and reproduction. This system can be obtained by the internet web browser and it can transfer data in real time through the network, it is also able to work autonomous having a back in communicating and electrical energy feeding, getting a better continuous diagnostic service and the autotransformer.

  12. Los paisajes de dehesa de la provincia de Ciudad Real. Caracterización y valoración biogeográfica a través de la metodología LANBIOEVA

    Directory of Open Access Journals (Sweden)

    María Cristina Díaz Sanz

    2017-01-01

    Full Text Available El paisaje de dehesa se configura como un mosaico arbolado en el que la transformación del me- dio ha sido secular. Esta característica y la configuración de un paisaje cultural no es óbice para que dentro de estas formaciones existan unos valores de raigambre ambiental y ecológica, junto a otros de tipo cultural. Todo ello hace que sean especialmente biodiversos y, por tanto, uno de los ecosistemas que mayor interés científico y social despierta. Es precisamente este interés el que nos lleva a caracterizar y valorar los espacios de dehesa de la provincia de Ciudad Real a través de la metodología LANBIOEVA ( Landscape Biogeographic Evaluation . En este sentido, se aplica este método de forma sistemática a estos bosques culturales y se obtienen los valores para cada uno de los criterios analizados de manera que pueden ser comparados con los de otras formaciones analizadas a escala global. La evaluación de estos paisajes tan singulares pretende testar dicho método en este tipo de condiciones. Los resultados muestran que los grupos de criterios más ambientalistas o ecológicos cuentan con unas cifras muy parecidas a las formaciones boscosas mejor conservadas dentro del ámbito ibérico. Los valores culturales, por su parte, muestran pun- tuaciones superiores, lo que hace que, en general, la suma de los criterios naturales, culturales y estructurales sean bastante elevados. En este sector, las amenazas no son excesivamente altas de manera que el valor final, por su parte, muestra unas cifras más modestas.

  13. Real-time phase contrast magnetic resonance imaging for assessment of haemodynamics: from phantom to patients

    Energy Technology Data Exchange (ETDEWEB)

    Traber, Julius; Wurche, Lennart; Dieringer, Matthias A.; Utz, Wolfgang; Knobelsdorff-Brenkenhoff, Florian von; Schulz-Menger, Jeanette [Max-Delbrueck-Centrum and Charite -Medical University Berlin and HELIOS Klinikum Berlin-Buch, Department of Cardiology and Nephrology, Working Group on Cardiovascular Magnetic Resonance Imaging, Experimental and Clinical Research Center, Berlin (Germany); Greiser, Andreas [Siemens AG Healthcare Sector, Erlangen (Germany); Jin, Ning [Siemens Medical Solutions USA, Inc., Columbus, OH (United States)

    2016-04-15

    Assessment of haemodynamics is crucial in many cardiac diseases. Phase contrast MRI (PC-MRI) can accurately access it. Arrhythmia is a major limitation in conventional segmented PC-MRI (SEG). A real-time PC-MRI sequence (RT) could overcome this. We validated RT by comparing to SEG. A prototype RT using shared velocity encoding was tested against SEG at 1.5 T in a flow phantom and consecutively included patients with (n = 55) or without (n = 59) aortic valve disease. In patients with atrial fibrillation (Afib, n = 15), only RT was applied. Phantom: PC images were acquired in front of and behind an interchangeable aortic-stenosis-like inlay. Mean velocity and flow were quantified. Patients: PC images were acquired in the ascending aorta, pulmonary trunk and superior caval vein. Peak velocity, stroke volume and regurgitant fraction were quantified. Phantom: Mean velocities (11 ± 1 to 207 ± 10 cm/s) and flow correlated closely between SEG and RT (r ≥ 0.99, ICC ≥ 0.98, p < 0.0005). Patients without AVD or with aortic regurgitation: Concordance of SEG and RT was excellent regarding peak velocities, stroke volumes (r ≥ 0.91, ICC ≥ 0.94, p < 0.0005) and regurgitant fractions (r = 0.95, ICC = 0.95, p < 0.0005). RT was feasible in all patients with Afib. The real-time sequence is accurate compared to conventional segmented PC-MRI. Its applicability in Afib was shown. Real-time PC-MRI might become a valuable tool in arrhythmia. (orig.)

  14. An assessment of the potential of PFEM-2 for solving long real-time industrial applications

    Science.gov (United States)

    Gimenez, Juan M.; Ramajo, Damián E.; Márquez Damián, Santiago; Nigro, Norberto M.; Idelsohn, Sergio R.

    2017-07-01

    The latest generation of the particle finite element method (PFEM-2) is a numerical method based on the Lagrangian formulation of the equations, which presents advantages in terms of robustness and efficiency over classical Eulerian methodologies when certain kind of flows are simulated, especially those where convection plays an important role. These situations are often encountered in real engineering problems, where very complex geometries and operating conditions require very large and long computations. The advantages that the parallelism introduced in the computational fluid dynamics making affordable computations with very fine spatial discretizations are well known. However, it is not possible to have the time parallelized, despite the effort that is being dedicated to use space-time formulations. In this sense, PFEM-2 adds a valuable feature in that its strong stability with little loss of accuracy provides an interesting way of satisfying the real-life computation needs. After having already demonstrated in previous publications its ability to achieve academic-based solutions with a good compromise between accuracy and efficiency, in this work, the method is revisited and employed to solve several nonacademic problems of technological interest, which fall into that category. Simulations concerning oil-water separation, waste-water treatment, metallurgical foundries, and safety assessment are presented. These cases are selected due to their particular requirements of long simulation times and or intensive interface treatment. Thus, large time-steps may be employed with PFEM-2 without compromising the accuracy and robustness of the simulation, as occurs with Eulerian alternatives, showing the potentiality of the methodology for solving not only academic tests but also real engineering problems.

  15. ¡Los carlistas en Palacio¡ La depuración política de la Capilla Real (1834-1835

    Directory of Open Access Journals (Sweden)

    Antonio Manuel Moral Roncal

    2004-01-01

    Full Text Available El proceso de implantación del liberalismo en España no sólo estuvo marcado por su larga duración, sino también por su alto grado de violencia. En consecuencia, cada alternativa de poder se vio seguida de un proceso de rigor que no sólo implicó la exclusión del enemigo político de la vida pública, sino también su persecución física y exilio. La corte fue una parte del amplio ámbito de poder del monarca. Por ello, entre 1832 y 1835, los partidarios de María Cristina, para el triunfo de sus ideas, consideraron necesario depurar ¡a Real Casa y Patrimonio de sus adversarios, reconociendo, de esta manera, la importancia definitiva de este espacio de poder. Y es que el rechazo o el apoyo de la Corona a una determinada opción política fue un factor decisivo —entre muchos otros— para su triunfo durante ese período de tiempo. El presente articulo se centra en la depuración realizada en una significativa sección palatina: la Capilla Real.The process oí liberalism s installation in Spain was not only marked by its long duration, but also for its high degree of violence. In consequence, each alternative of power was followed by a rigor process that didn't only imply the exclusión of the political enemy of public Ufe, but also its physical persecution and exile. The court was a part of the wide environment ofking's power. For it, between 1832 and 1835, those in favor of María Cristina, for the victory of their ideas, considered necessary to purífy the Royal House and Patrimony recognizing, in this way, the definitive importance of this power space. And it is that the rejection or the support of the Crown to a certain political option were a decisivo factor —many other— for their victory during that period. The present articulates it is centered in the purification carried out in a significant palatino section: the Royal Chapel.

  16. Development of an intelligent hydroinformatic system for real-time monitoring and assessment of civil infrastructure

    Science.gov (United States)

    Cahill, Paul; Michalis, Panagiotis; Solman, Hrvoje; Kerin, Igor; Bekic, Damir; Pakrashi, Vikram; McKeogh, Eamon

    2017-04-01

    With the effects of climate change becoming more apparent, extreme weather events are now occurring with greater frequency throughout the world. Such extreme events have resulted in increased high intensity flood events which are having devastating consequences on hydro-structures, especially on bridge infrastructure. The remote and often inaccessible nature of such bridges makes inspections problematic, a major concern if safety assessments are required during and after extreme flood events. A solution to this is the introduction of smart, low cost sensing solutions at locations susceptible to hydro-hazards. Such solutions can provide real-time information on the health of the bridge and its environments, with such information aiding in the mitigation of the risks associated with extreme weather events. This study presents the development of an intelligent system for remote, real-time monitoring of hydro-hazards to bridge infrastructure. The solution consists of two types of remote monitoring stations which have the capacity to monitor environmental conditions and provide real-time information to a centralized, big data database solution, from which an intelligent decision support system will accommodate the results to control and manage bridge, river and catchment assets. The first device developed as part of the system is the Weather Information Logging Device (WILD), which monitors rainfall, temperature and air and soil moisture content. The ability of the WILD to monitor rainfall in real time enables flood early warning alerts and predictive river flow conditions, thereby enabling decision makers the ability to make timely and effective decisions about critical infrastructures in advance of extreme flood events. The WILD is complemented by a second monitoring device, the Bridge Information Recording Device (BIRD), which monitors water levels at a given location in real-time. The monitoring of water levels of a river allows for, among other applications

  17. Noninvasive Real-Time Assessment of Cell Viability in a Three-Dimensional Tissue.

    Science.gov (United States)

    Mahfouzi, Seyed Hossein; Amoabediny, Ghassem; Doryab, Ali; Safiabadi-Tali, Seyed Hamid; Ghanei, Mostafa

    2018-04-01

    Maintaining cell viability within 3D tissue engineering scaffolds is an essential step toward a functional tissue or organ. Assessment of cell viability in 3D scaffolds is necessary to control and optimize tissue culture process. Monitoring systems based on respiration activity of cells (e.g., oxygen consumption) have been used in various cell cultures. In this research, an online monitoring system based on respiration activity was developed to monitor cell viability within acellular lung scaffolds. First, acellular lung scaffolds were recellularized with human umbilical cord vein endothelial cells, and then, cell viability was monitored during a 5-day period. The real-time monitoring system generated a cell growth profile representing invaluable information on cell viability and proliferative states during the culture period. The cell growth profile obtained by the monitoring system was consistent with 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide analysis and glucose consumption measurement. This system provided a means for noninvasive, real-time, and repetitive investigation of cell viability. Also, we showed the applicability of this monitoring system by introducing shaking as an operating parameter in a long-term culture.

  18. Sexual and Gender Minority Youth in Foster Care: Assessing Disproportionality and Disparities in Los Angeles

    OpenAIRE

    Wilson, Bianca DM; Cooper, Khush; Kastanis, Angeliki; Nezhad, Sheila

    2014-01-01

    LGBTQ foster youth are twice as likely to report poor treatment and more likely to live in group homes and to have more foster care placements. Approximately 1 in 5, or 1,400 foster youth in Los Angeles County, home to the nation’s largest population of foster youth, identify as LGBTQ. The finding is twice the estimated percentage of youth not in foster care who are LGBTQ. Generally, LGBTQ foster youth mirror the racial/ethnic demographic of all foster youth in Los Angeles County. The majorit...

  19. Environmental Assessment. Proposed Air Force Space Division Housing Project, White Point, Los Angeles, California

    Science.gov (United States)

    1984-07-01

    render any potential impactsnegligible. 5 E. Diking, Dredging and Shoreline Structures The project would have no effect on these areas of concern; see3...San Juan Capistrano Indians of Southern California [1812-1826]") and Hugo Reid’s letters I printed in the Los Angeles Star in the 1800’s ( Heizer 1968...California5 n.d. A Brief History of Fort MacArthur. Heizer , R. F. (ed.) 1968 The Indians of Los Angeles County: Hugo Reid’s Letters of 1852

  20. Assessment of Real Heat Transfer Coefficients through Shell and Tube and Plate Heat Exchangers

    Directory of Open Access Journals (Sweden)

    Dan CONSTANTINESCU

    2011-07-01

    Full Text Available The purpose of this paper is to present a procedure used in the assessment of the real heat transfer characteristic of shell and tube and plate heat exchangers. The theoretical fundamentals of the procedure are introduced as well as the measured data collection and processing. The theoretical analysis is focused on the adoption of criterial equations which, subjected to certain verification criteria presented in the paper, provide the most credible value of the convection heat transfer coefficients inside the circular and flat tubes. In the end two case studies are presented, one concerning a shell and tube heat exchanger operational at INCERC Thermal Substation and the other concerning a plate heat exchanger tested on the Laboratory Stand of the Department of Building Services and Efficient Use of Energy in Buildings of INCERC Bucharest.

  1. High-resolution real-time sonography and MR imaging in assessment of osteocartilaginous exostoses

    International Nuclear Information System (INIS)

    Prayer, L.M.; Kropej, D.H.; Wimberger, D.M.; Wurnig, C.F.; Kramer, J.; Kainberger, F.M.; Braun, O.H.; Ritschl, P.W.; Imhof, H.

    1991-01-01

    High-resolution real-time ultrasonography (US) and MR imaging, using both spin-echo (SE) and gradient-echo (GE) sequences, were performed prospectively in 14 patients with solitary osteocartilaginous exostoses to assess cartilage cap thickness and bursa formation. Results were compared to surgical and histopathologic findings in all cases. Both US and MR imaging were useful in evaluating exostotic cartilage cap thickness, which is supposed to be the most reliable sign of malignant transformation. Hyaline cartilage matrix had distinctive features in US and MR imaging caused by its specific histologic composition. The formation of bursae over the protruding exostoses, which results in pain and clinically could raise the suspicion of growth and malignant transformation, was demonstrated best using GE sequences. MR imaging was thus superior to US in the detection of bursa formation. (orig.)

  2. The Rational Expectations Hypothesis: An assessment on its real world application

    Directory of Open Access Journals (Sweden)

    Santiago Tobón

    2014-12-01

    Full Text Available The Rational Expectations Hypothesis was first developed as a theoretical technique aimed at explaining agents’ behavior in a given environment. In particular, it describes how the outcome of a given economic phenomenon depends to a certain degree on what agents expect to happen. Subsequently, it was introduced into macroeconomic models as a way to explain the ineffectiveness of monetary policy. Since then, most of these models have been based on the rational expectations assumption. This paper assesses the real life application of this feature based on two arguments: the determination of an objective reality through beliefs and subjective expectations; and the exclusion of the evolution of human knowledge and innovation in macroeconomic models.

  3. Imaging techniques used for the real-time assessment of angiogenesis in digestive cancers

    DEFF Research Database (Denmark)

    Săftoiu, Adrian; Vilmann, Peter

    2011-01-01

    Angiogenesis has a critical role in primary tumor growth and the development of metastases. Several angiogenesis inhibitors were recently developed, being a very attractive target for digestive tumor therapy. However, individualized therapy should not only be based on the pre-treatment imaging...... evaluation, but also on sensitive monitoring of microvascular changes during treatment. State-of-the-art imaging techniques have the potential to visualize and characterize angiogenesis, although the technology and methodologies employed are recent and need further validation. The aim of this series...... of reviews was to analyze and enhance current knowledge and future perspectives about the real-time assessment of angiogenesis in digestive cancers, used for the longitudinal monitoring of the effects of chemo-radiotherapy (including anti-angiogenic therapies), as well as for the precise targeting of drugs...

  4. High-resolution real-time sonography and MR imaging in assessment of osteocartilaginous exostoses

    Energy Technology Data Exchange (ETDEWEB)

    Prayer, L.M.; Kropej, D.H.; Wimberger, D.M.; Wurnig, C.F.; Kramer, J.; Kainberger, F.M.; Braun, O.H.; Ritschl, P.W.; Imhof, H. (Vienna Univ. (Austria). Depts. of Radiology, Orthopedic Surgery, Pathology, and the MR Inst.)

    1991-09-01

    High-resolution real-time ultrasonography (US) and MR imaging, using both spin-echo (SE) and gradient-echo (GE) sequences, were performed prospectively in 14 patients with solitary osteocartilaginous exostoses to assess cartilage cap thickness and bursa formation. Results were compared to surgical and histopathologic findings in all cases. Both US and MR imaging were useful in evaluating exostotic cartilage cap thickness, which is supposed to be the most reliable sign of malignant transformation. Hyaline cartilage matrix had distinctive features in US and MR imaging caused by its specific histologic composition. The formation of bursae over the protruding exostoses, which results in pain and clinically could raise the suspicion of growth and malignant transformation, was demonstrated best using GE sequences. MR imaging was thus superior to US in the detection of bursa formation. (orig.).

  5. A Systematic Approach for Real-Time Operator Functional State Assessment

    Science.gov (United States)

    Zhang, Guangfan; Wang, Wei; Pepe, Aaron; Xu, Roger; Schnell, Thomas; Anderson, Nick; Heitkamp, Dean; Li, Jiang; Li, Feng; McKenzie, Frederick

    2012-01-01

    A task overload condition often leads to high stress for an operator, causing performance degradation and possibly disastrous consequences. Just as dangerous, with automated flight systems, an operator may experience a task underload condition (during the en-route flight phase, for example), becoming easily bored and finding it difficult to maintain sustained attention. When an unexpected event occurs, either internal or external to the automated system, the disengaged operator may neglect, misunderstand, or respond slowly/inappropriately to the situation. In this paper, we discuss an approach for Operator Functional State (OFS) monitoring in a typical aviation environment. A systematic ground truth finding procedure has been designed based on subjective evaluations, performance measures, and strong physiological indicators. The derived OFS ground truth is continuous in time compared to a very sparse estimation of OFS based on an expert review or subjective evaluations. It can capture the variations of OFS during a mission to better guide through the training process of the OFS assessment model. Furthermore, an OFS assessment model framework based on advanced machine learning techniques was designed and the systematic approach was then verified and validated with experimental data collected in a high fidelity Boeing 737 simulator. Preliminary results show highly accurate engagement/disengagement detection making it suitable for real-time applications to assess pilot engagement.

  6. Rapid quality assessment of Radix Aconiti Preparata using direct analysis in real time mass spectrometry.

    Science.gov (United States)

    Zhu, Hongbin; Wang, Chunyan; Qi, Yao; Song, Fengrui; Liu, Zhiqiang; Liu, Shuying

    2012-11-08

    This study presents a novel and rapid method to identify chemical markers for the quality control of Radix Aconiti Preparata, a world widely used traditional herbal medicine. In the method, the samples with a fast extraction procedure were analyzed using direct analysis in real time mass spectrometry (DART MS) combined with multivariate data analysis. At present, the quality assessment approach of Radix Aconiti Preparata was based on the two processing methods recorded in Chinese Pharmacopoeia for the purpose of reducing the toxicity of Radix Aconiti and ensuring its clinical therapeutic efficacy. In order to ensure the safety and effectivity in clinical use, the processing degree of Radix Aconiti should be well controlled and assessed. In the paper, hierarchical cluster analysis and principal component analysis were performed to evaluate the DART MS data of Radix Aconiti Preparata samples in different processing times. The results showed that the well processed Radix Aconiti Preparata, unqualified processed and the raw Radix Aconiti could be clustered reasonably corresponding to their constituents. The loading plot shows that the main chemical markers having the most influence on the discrimination amongst the qualified and unqualified samples were mainly some monoester diterpenoid aconitines and diester diterpenoid aconitines, i.e. benzoylmesaconine, hypaconitine, mesaconitine, neoline, benzoylhypaconine, benzoylaconine, fuziline, aconitine and 10-OH-mesaconitine. The established DART MS approach in combination with multivariate data analysis provides a very flexible and reliable method for quality assessment of toxic herbal medicine. Copyright © 2012 Elsevier B.V. All rights reserved.

  7. Assessing the benefits of residential demand response in a real time distribution energy market

    International Nuclear Information System (INIS)

    Siano, Pierluigi; Sarno, Debora

    2016-01-01

    Highlights: • A new probabilistic methodology, integrating DR in a distribution energy market is proposed. • The method can alleviate distribution network congestions. • This method based on D-LMPs allows cost savings for end-user customers. • Innovative thermal and shiftable loads Real Time control algorithms are also presented. - Abstract: In the field of electricity distribution networks and with the advent of smart grids and microgrids, the use of Distribution Locational Marginal Price (D-LMPs) in a Real Time (RT) distribution market managed by a Distribution System Operator (DSO) is discussed in presence of empowered residential end-users that are able to bid for energy by a demand aggregator while following Demand Response (DR) initiatives. Each customer is provided by a transactive controller, which reads the locational market signals and answers with a bid taking into account the user preferences about some appliances involved in DR activities and controlled by smart plugs-in. In particular, Heating Ventilation and Air Conditioning (HVAC) appliances and shiftable loads are controlled so that their consumption profile can be modified according to the price of energy. In order to assess the effectiveness of the proposed method in terms of energy and cost saving, an innovative probabilistic methodology for evaluating the impact of residential DR choices considering uncertainties related to load demand, user preferences, environmental conditions, house thermal behavior and wholesale market trends has been proposed. The uncertainties related to the stochastic variations of the variables involved are modeled by using the Monte Carlo Simulation (MCS) method. The combination of MCS and RT distribution market simulation based on D-LMPs are used to assess the operation and impact of the DR method over one month. Simulations results on an 84-buses distribution network confirmed that the proposed method allows saving costs for residential end-users and making

  8. Comparative life cycle assessment of real pilot reactors for microalgae cultivation in different seasons

    International Nuclear Information System (INIS)

    Pérez-López, Paula; De Vree, Jeroen H.; Feijoo, Gumersindo; Bosma, Rouke; Barbosa, Maria J.; Moreira, María Teresa; Wijffels, René H.; Van Boxtel, Anton J.B.; Kleinegris, Dorinde M.M.

    2017-01-01

    Highlights: •Life cycle assessment was used to compare 3 real pilot systems for algae cultivation. •The temperature control system was the main contributor to environmental impacts. •Tubular reactors had lower impacts per unit of biomass produced than open pond. •Meteorological conditions on the reactors played a critical role in LCA results. •Environmental impact reductions of 17–90% were estimated for optimized full-scale reactors. -- Abstract: Microalgae are promising natural resources for biofuels, chemical, food and feed products. Besides their economic potential, the environmental sustainability must be examined. Cultivation has a significant environmental impact that depends on reactor selection and operating conditions. To identify the main environmental bottlenecks for scale-up to industrial facilities this study provides a comparative life cycle assessment (LCA) of open raceway ponds and tubular photobioreactors at pilot scale. The results are based on experimental data from real pilot plants operated in summer, fall and winter at AlgaePARC (Wageningen, The Netherlands). The energy consumption for temperature regulation presented the highest environmental burden. The production of nutrients affected some categories. Despite limited differences compared to the vertical system, the horizontal PBR was found the most efficient in terms of productivity and environmental impact. The ORP was, given the Dutch climatic conditions, only feasible under summer operation. The results highlight the relevance of LCA as a tool for decision-making in process design. Weather conditions and availability of sources for temperature regulation were identified as essential factors for the selection of geographic locations and for microalgal cultivation systems based on environmental criteria. Simulation of large-scale reactors with optimized temperature regulation systems lead to environmental improvements and energy demand reductions ranging from 17% up to 90% for

  9. Trabajo de campo en un paisaje minero: los desafíos de Real de Catorce, San Luis Potosí

    Directory of Open Access Journals (Sweden)

    Geronimo Barrera de la Torre

    2015-01-01

    Full Text Available Uno de los procesos más significativos que atraviesa México en la última década, es la expansión de la actividad minera por parte de empresas de capital extranjero, principalmente canadiense. En este contexto, antiguos sitios mineros son considerados nuevamente para la extracción de metales con tecnologías modernas, que permiten explotar tanto los yacimientos como los jales o desperdicios de anteriores operaciones mineras.

  10. Assessing the impacts of implementing lean construction Evaluando los impactos de la implementación de lean construction

    Directory of Open Access Journals (Sweden)

    Luis F Alarcón

    2008-04-01

    Full Text Available Over the last 10 years an increasing number of companies have implemented lean construction practices in an attempt to improve performance in construction projects. Most companies, and also some researchers, have reported satisfactory results from their implementation. However, there is still a need to provide more extensive analysis of the empirical evidence available to assess the impact of the implementation of lean construction. The authors have researched the implementation of the Last Planner System and other Lean Construction techniques in over one hundred construction projects over the last five years. They have also developed strategies and support tools for implementation. This paper analyzes some of the main impacts observed in the studied projects, and some of the lessons learned from implementations. The paper discusses difficulties and barriers for implementation, productivity improvements, variability reduction and effectiveness of implementation strategies. The paper also provides recommendations for future implementation and researchEn los últimos 10 años un creciente número de empresas constructoras ha implementado prácticas de Lean Construction para mejorar el desempeño de sus proyectos. La mayor parte de estas empresas, y también algunos investigadores, han informado sobre buenos resultados obtenidos en los proyectos. Sin embargo, todavía es necesario un análisis más completo de la evidencia empírica disponible para evaluar así el impacto de Lean Construction en los proyectos y empresas. Los autores han investigado la implementación del Sistema Ultimo Planificador y otras técnicas de Lean Construction en mas de un centenar de proyectos en los últimos 5 años y han desarrollado estrategias y herramientas de apoyo para su implementación. Este artículo analiza algunos de los principales impactos observados en los proyectos estudiados y las lecciones aprendidas en este proceso. Se discuten dificultades y barreras

  11. Los maestros de obras aprobados por la Real Academia de Bellas Artes de San Fernando (1816-1858 : una profesión en continuo conflicto con los arquitectos

    Directory of Open Access Journals (Sweden)

    Rosario Santamaría Almolda

    2000-01-01

    Full Text Available Los maestros de obras fueron unos profesionales titulados a los cuales la legislación les reconoció una serie de facultades para diseñar y dirigir construcciones. Estas facultades provocaron a lo largo del siglo xix un continuo conflicto de competencias profesionales con los arquitectos. Tenían los maestros de obras menos conocimientos y estudios que los arquitectos por sus menos años de carrera, pero con suficiente capacidad científica para proyectar. Estos diplomados después de un período de formación en las Academias o en los estudios de los arquitectos y, posterioremente en la Escuela Especial de Arquitectura, sabían conjugar la teoría con la práctica.The work managers were qualified professionals with less knowledges than the architects but with enought scientific capacity for making a proyect. The law admited that they were able to design and run a construction proyect and this will produce in the xix century a clash of professional competences between architecs and works managers as this work managers after a period of studies in academies or in the office of the architecs, and after that in the Special School of Architecture, were able to put together theory and practique.

  12. Biological Assessment of the Continued Operation of Los Alamos National Laboratory on Federally Listed Threatened and Endangered Species

    Energy Technology Data Exchange (ETDEWEB)

    Hansen, Leslie A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States). Ecology and Air Quality Group

    2006-09-19

    This biological assessment considers the effects of continuing to operate Los Alamos National Laboratory on Federally listed threatened or endangered species, based on current and future operations identified in the 2006 Site-wide Environmental Impact Statement for the Continued Operation of Los Alamos National Laboratory (SWEIS; DOE In Prep.). We reviewed 40 projects analyzed in the SWEIS as well as two aspects on ongoing operations to determine if these actions had the potential to affect Federally listed species. Eighteen projects that had not already received U.S. Fish and Wildlife Service (USFWS) consultation and concurrence, as well as the two aspects of ongoing operations, ecological risk from legacy contaminants and the Outfall Reduction Project, were determined to have the potential to affect threatened or endangered species. Cumulative impacts were also analyzed.

  13. An assessment of Microtox trademark as a biomonitoring tool for whole effluent testing for Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Zachritz, W.H. II; Morrow, J.

    1994-01-01

    Los Alamos National Laboratory (LANL) has special discharge problems relating to potential radioactive content of the effluent discharge waters. Because of this all testing must be performed on-site and results must be rapidly determined. There is a need to examine the development of a real-time procedure for effluent biomonitoring to met these site limitations. The Microtox trademark unit for toxicity testing is a microbially-based test system that shows great promise to be used for WET testing. The overall goal of this study is to develop an acceptable protocol for operational biomonitoring using the Microtox trademark toxicity test for LANL. The specific objectives include: development of an appropriate toxicity testing protocol using the Microtox trademark toxicity test for whole effluent toxicity testing and evaluation of the protocol based on factors such as sensitivity, response time, cost of analysis, and simplicity of operation

  14. A Dynamic Speech Comprehension Test for Assessing Real-World Listening Ability.

    Science.gov (United States)

    Best, Virginia; Keidser, Gitte; Freeston, Katrina; Buchholz, Jörg M

    2016-07-01

    Many listeners with hearing loss report particular difficulties with multitalker communication situations, but these difficulties are not well predicted using current clinical and laboratory assessment tools. The overall aim of this work is to create new speech tests that capture key aspects of multitalker communication situations and ultimately provide better predictions of real-world communication abilities and the effect of hearing aids. A test of ongoing speech comprehension introduced previously was extended to include naturalistic conversations between multiple talkers as targets, and a reverberant background environment containing competing conversations. In this article, we describe the development of this test and present a validation study. Thirty listeners with normal hearing participated in this study. Speech comprehension was measured for one-, two-, and three-talker passages at three different signal-to-noise ratios (SNRs), and working memory ability was measured using the reading span test. Analyses were conducted to examine passage equivalence, learning effects, and test-retest reliability, and to characterize the effects of number of talkers and SNR. Although we observed differences in difficulty across passages, it was possible to group the passages into four equivalent sets. Using this grouping, we achieved good test-retest reliability and observed no significant learning effects. Comprehension performance was sensitive to the SNR but did not decrease as the number of talkers increased. Individual performance showed associations with age and reading span score. This new dynamic speech comprehension test appears to be valid and suitable for experimental purposes. Further work will explore its utility as a tool for predicting real-world communication ability and hearing aid benefit. American Academy of Audiology.

  15. Real-time ultrasound elastography: an assessment of enlarged cervical lymph nodes.

    Science.gov (United States)

    Lo, Wu-Chia; Cheng, Po-Wen; Wang, Chi-Te; Liao, Li-Jen

    2013-09-01

    To determine the efficacy of real-time elastography (RTE), compared with our previously proposed prediction model, in the detection of malignancy in cervical lymph nodes (LNs). One hundred and thirty-one patients underwent ultrasound-guided fine needle aspiration biopsy (ultrasound FNAB) after ultrasound and RTE evaluation. The formula of the RTE scoring system was a four-point visual scale, based on a previously determined model. The formula of the prediction model was: [Formula: see text]. An extended model was constructed with four previous predictors and elasticity scores, using a logistic regression model. Final histology revealed 77 benign and 54 malignant LNs. In the elasticity score system, sensitivity was 66.7 %, specificity was 57.1 %, the positive predictive value (PPV) was 52.2 % and the negative predictive value (NPV) was 71.0 %. In the prediction model system, sensitivity was 79.6 %, specificity was 92.2 %, the PPV was 87.8 % and the NPV was 86.6 %. When the extended and the original model were compared, the areas under the receiver operating characteristic curve (c-statistic) was 0.94 and 0.95, respectively (P > 0.05). Qualitative RTE offers no additional value over conventional ultrasound in predicting malignancy in cervical LNs. • An ultrasound system can help in the assessment of cervical lymph nodes. • Grey-scale and power Doppler ultrasound remain fundamental for neck nodal evaluation. • Qualitative real-time elastography provided no additional value compared with current prediction models.

  16. Environmental Assessment for Leasing Land for the Siting, Construction and Operation of a Commercial AM Radio Antenna at Los Alamos National Laboratory, Los Alamos, NM

    Energy Technology Data Exchange (ETDEWEB)

    N/A

    2000-02-16

    The United States (U.S.) Department of Energy (DOE) proposes to lease approximately 3 acres of land at the Los Alamos National Laboratory (LANL) on the southeast tip of Technical Area (TA) 54 for the siting, construction and operation of an AM radio broadcasting antenna. This Environmental Assessment (EA) has been developed in order to assess the environmental effects of the Proposed Action and No Action alternative. The Proposed Action includes the lease of land for the siting, construction and operation of an AM radio broadcasting antenna in TA-54, just north of Pajarito Road and State Highway 4. The No Action Alternative was also considered. Under the No Action Alternative, DOE would not lease land on LANL property for the siting and operation of an AM radio broadcasting antenna; the DOE would not have a local station for emergency response use; and the land would continue to be covered in native vegetation and serve as a health and safety buffer zone for TA-54 waste management activities. Other potential sites on LANL property were evaluated but dismissed for reasons such as interference with sensitive laboratory experiments. Potential visual, health, and environmental effects are anticipated to be minimal for the Proposed Action. The radio broadcasting antenna would be visible against the skyline from some public areas, but would be consistent with other man-made objects in the vicinity that partially obstruct viewsheds (e.g. meteorological tower, power lines). Therefore, the net result would be a modest change of the existing view. Electromagnetic field (EMF) emissions from the antenna would be orders or magnitude less than permissible limits. The proposed antenna construction would not affect known cultural sites, but is located in close proximity to two archaeological sites. Construction would be monitored to ensure that the associated road and utility corridor would avoid cultural sites.

  17. The undergraduate physics tutorial program at CSU Los Angeles assessment of utility and areas of interest

    Science.gov (United States)

    Avetyan, Smbat

    The Physics Education Research (PER) group at the University of Washington have researched traditional teaching methods and found that students in introductory physics are lacking a conceptual understanding of the physics material. The solution they put forth is an interactive tutorial program designed to meet the lack of conceptual understanding. Since the tutorial programs inception at CSU Los Angeles in Fall 2006 no evaluation has been successfully undertaken therefore the effect of the tutorial program in the physics 200 series is deeply obscure to the department. The research has shed light on the tutorial program and brought into context its effectiveness on the overall physics 200 series courses at CSU Los Angeles. The researcher has addressed the following research questions, what overall effect does the tutorial program have on the Physics 200 series curriculum? What is the size and significance of gains attributable to the undergraduate calculus based Physics 200 series tutorial program at CSU Los Angeles? What can we learn from gains about individual weekly lessons from the Physics 200 series tutorial courses? What is the correlation of tutorial gains with student final course grades? Are the gains from the tutorial program different for genders? Is there a difference in gains based on the different students' colleges?

  18. Computer-assisted assessment of ultrasound real-time elastography: initial experience in 145 breast lesions.

    Science.gov (United States)

    Zhang, Xue; Xiao, Yang; Zeng, Jie; Qiu, Weibao; Qian, Ming; Wang, Congzhi; Zheng, Rongqin; Zheng, Hairong

    2014-01-01

    To develop and evaluate a computer-assisted method of quantifying five-point elasticity scoring system based on ultrasound real-time elastography (RTE), for classifying benign and malignant breast lesions, with pathologic results as the reference standard. Conventional ultrasonography (US) and RTE images of 145 breast lesions (67 malignant, 78 benign) were performed in this study. Each lesion was automatically contoured on the B-mode image by the level set method and mapped on the RTE image. The relative elasticity value of each pixel was reconstructed and classified into hard or soft by the fuzzy c-means clustering method. According to the hardness degree inside lesion and its surrounding tissue, the elasticity score of the RTE image was computed in an automatic way. Visual assessments of the radiologists were used for comparing the diagnostic performance. Histopathologic examination was used as the reference standard. The Student's t test and receiver operating characteristic (ROC) curve analysis were performed for statistical analysis. Considering score 4 or higher as test positive for malignancy, the diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were 93.8% (136/145), 92.5% (62/67), 94.9% (74/78), 93.9% (62/66), and 93.7% (74/79) for the computer-assisted scheme, and 89.7% (130/145), 85.1% (57/67), 93.6% (73/78), 92.0% (57/62), and 88.0% (73/83) for manual assessment. Area under ROC curve (Az value) for the proposed method was higher than the Az value for visual assessment (0.96 vs. 0.93). Computer-assisted quantification of classical five-point scoring system can significantly eliminate the interobserver variability and thereby improve the diagnostic confidence of classifying the breast lesions to avoid unnecessary biopsy. Copyright © 2013 Elsevier Ireland Ltd. All rights reserved.

  19. Computer-assisted assessment of ultrasound real-time elastography: Initial experience in 145 breast lesions

    Energy Technology Data Exchange (ETDEWEB)

    Zhang, Xue; Xiao, Yang [Shenzhen Key Lab for Molecular Imaging, Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen (China); Zeng, Jie [Department of Medical Ultrasonics, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou (China); Qiu, Weibao; Qian, Ming; Wang, Congzhi [Shenzhen Key Lab for Molecular Imaging, Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen (China); Zheng, Rongqin, E-mail: zhengronggin@hotmail.com [Department of Medical Ultrasonics, Third Affiliated Hospital of Sun Yat-Sen University, Guangzhou (China); Zheng, Hairong, E-mail: hr.zheng@siat.ac.cn [Shenzhen Key Lab for Molecular Imaging, Paul C. Lauterbur Research Center for Biomedical Imaging, Institute of Biomedical and Health Engineering, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen (China)

    2014-01-15

    Purpose: To develop and evaluate a computer-assisted method of quantifying five-point elasticity scoring system based on ultrasound real-time elastography (RTE), for classifying benign and malignant breast lesions, with pathologic results as the reference standard. Materials and methods: Conventional ultrasonography (US) and RTE images of 145 breast lesions (67 malignant, 78 benign) were performed in this study. Each lesion was automatically contoured on the B-mode image by the level set method and mapped on the RTE image. The relative elasticity value of each pixel was reconstructed and classified into hard or soft by the fuzzy c-means clustering method. According to the hardness degree inside lesion and its surrounding tissue, the elasticity score of the RTE image was computed in an automatic way. Visual assessments of the radiologists were used for comparing the diagnostic performance. Histopathologic examination was used as the reference standard. The Student's t test and receiver operating characteristic (ROC) curve analysis were performed for statistical analysis. Results: Considering score 4 or higher as test positive for malignancy, the diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) were 93.8% (136/145), 92.5% (62/67), 94.9% (74/78), 93.9% (62/66), and 93.7% (74/79) for the computer-assisted scheme, and 89.7% (130/145), 85.1% (57/67), 93.6% (73/78), 92.0% (57/62), and 88.0% (73/83) for manual assessment. Area under ROC curve (A{sub z} value) for the proposed method was higher than the A{sub z} value for visual assessment (0.96 vs. 0.93). Conclusion: Computer-assisted quantification of classical five-point scoring system can significantly eliminate the interobserver variability and thereby improve the diagnostic confidence of classifying the breast lesions to avoid unnecessary biopsy.

  20. Rapid quality assessment of Radix Aconiti Preparata using direct analysis in real time mass spectrometry

    Energy Technology Data Exchange (ETDEWEB)

    Zhu Hongbin; Wang Chunyan; Qi Yao [Changchun Center of Mass Spectrometry and Chemical Biology Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (China); University of Chinese Academy of Sciences, Beijing 100039 (China); Song Fengrui, E-mail: songfr@ciac.jl.cn [Changchun Center of Mass Spectrometry and Chemical Biology Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (China); Liu Zhiqiang; Liu Shuying [Changchun Center of Mass Spectrometry and Chemical Biology Laboratory, Changchun Institute of Applied Chemistry, Chinese Academy of Sciences, Changchun 130022 (China)

    2012-11-08

    Highlights: Black-Right-Pointing-Pointer DART MS combined with PCA and HCA was used to rapidly identify markers of Radix Aconiti. Black-Right-Pointing-Pointer The DART MS behavior of six aconitine-type alkaloids was investigated. Black-Right-Pointing-Pointer Chemical markers were recognized between the qualified and unqualified samples. Black-Right-Pointing-Pointer DART MS was shown to be an effective tool for quality control of Radix Aconiti Preparata. - Abstract: This study presents a novel and rapid method to identify chemical markers for the quality control of Radix Aconiti Preparata, a world widely used traditional herbal medicine. In the method, the samples with a fast extraction procedure were analyzed using direct analysis in real time mass spectrometry (DART MS) combined with multivariate data analysis. At present, the quality assessment approach of Radix Aconiti Preparata was based on the two processing methods recorded in Chinese Pharmacopoeia for the purpose of reducing the toxicity of Radix Aconiti and ensuring its clinical therapeutic efficacy. In order to ensure the safety and effectivity in clinical use, the processing degree of Radix Aconiti should be well controlled and assessed. In the paper, hierarchical cluster analysis and principal component analysis were performed to evaluate the DART MS data of Radix Aconiti Preparata samples in different processing times. The results showed that the well processed Radix Aconiti Preparata, unqualified processed and the raw Radix Aconiti could be clustered reasonably corresponding to their constituents. The loading plot shows that the main chemical markers having the most influence on the discrimination amongst the qualified and unqualified samples were mainly some monoester diterpenoid aconitines and diester diterpenoid aconitines, i.e. benzoylmesaconine, hypaconitine, mesaconitine, neoline, benzoylhypaconine, benzoylaconine, fuziline, aconitine and 10-OH-mesaconitine. The established DART MS approach in

  1. Rapid quality assessment of Radix Aconiti Preparata using direct analysis in real time mass spectrometry

    International Nuclear Information System (INIS)

    Zhu Hongbin; Wang Chunyan; Qi Yao; Song Fengrui; Liu Zhiqiang; Liu Shuying

    2012-01-01

    Highlights: ► DART MS combined with PCA and HCA was used to rapidly identify markers of Radix Aconiti. ► The DART MS behavior of six aconitine-type alkaloids was investigated. ► Chemical markers were recognized between the qualified and unqualified samples. ► DART MS was shown to be an effective tool for quality control of Radix Aconiti Preparata. - Abstract: This study presents a novel and rapid method to identify chemical markers for the quality control of Radix Aconiti Preparata, a world widely used traditional herbal medicine. In the method, the samples with a fast extraction procedure were analyzed using direct analysis in real time mass spectrometry (DART MS) combined with multivariate data analysis. At present, the quality assessment approach of Radix Aconiti Preparata was based on the two processing methods recorded in Chinese Pharmacopoeia for the purpose of reducing the toxicity of Radix Aconiti and ensuring its clinical therapeutic efficacy. In order to ensure the safety and effectivity in clinical use, the processing degree of Radix Aconiti should be well controlled and assessed. In the paper, hierarchical cluster analysis and principal component analysis were performed to evaluate the DART MS data of Radix Aconiti Preparata samples in different processing times. The results showed that the well processed Radix Aconiti Preparata, unqualified processed and the raw Radix Aconiti could be clustered reasonably corresponding to their constituents. The loading plot shows that the main chemical markers having the most influence on the discrimination amongst the qualified and unqualified samples were mainly some monoester diterpenoid aconitines and diester diterpenoid aconitines, i.e. benzoylmesaconine, hypaconitine, mesaconitine, neoline, benzoylhypaconine, benzoylaconine, fuziline, aconitine and 10-OH-mesaconitine. The established DART MS approach in combination with multivariate data analysis provides a very flexible and reliable method for quality

  2. Environmental Assessment for Lease of Land for the Development of a Research Park at Los Alamos National Laboratory, Los Alamos, New Mexico - Final Document

    Energy Technology Data Exchange (ETDEWEB)

    N/A

    1997-10-07

    As part of its initiative to fulfill its responsibilities to provide support for the incorporated County of Los Alamos (the County) as an Atomic Energy Community, while simultaneously fulfilling its obligations to enhance the self-sufficiency of the County under authority of the Atomic Energy Community Act of 1955 and the Defense Authorization Act, the U.S. Department of Energy (DOE) proposes to lease undeveloped land in Los Alamos, New Mexico, to the County for private sector use as a research park. The Proposed Action is intended to accelerate economic development activities within the County by creating regional employment opportunities through offering federal land for private sector lease and use. As a result of the proposed land lease, any government expenditures for providing infrastructure to the property would be somewhat supplemented by tenant purchase of Los Alamos National Laboratory (LANL) expertise in research and development activities. The presence of a research park within LANL boundaries is expected to allow private sector tenants of the park to be able to quickly and efficiently call upon LANL scientific expertise and facility and equipment capabilities as part of their own research operations and LANL research personnel, in turn, would be challenged in areas complementary to their federally funded research. In this way a symbiotic relationship would be enjoyed by both parties while simultaneously promoting economic development for the County through new job opportunities at the Research Park and at LANL, new indirect support opportunities for the community at large, and through payment of the basic building space leases. A ''sliding-scale'' approach (DOE 1993) is the basis for the analysis of effects in this Environmental Assessment (EA). That is, certain aspects of the Proposed Action have a greater potential for creating adverse environmental effects than others; therefore, they are discussed in greater detail in this EA

  3. Real-time flood forecasts & risk assessment using a possibility-theory based fuzzy neural network

    Science.gov (United States)

    Khan, U. T.

    2016-12-01

    Globally floods are one of the most devastating natural disasters and improved flood forecasting methods are essential for better flood protection in urban areas. Given the availability of high resolution real-time datasets for flood variables (e.g. streamflow and precipitation) in many urban areas, data-driven models have been effectively used to predict peak flow rates in river; however, the selection of input parameters for these types of models is often subjective. Additionally, the inherit uncertainty associated with data models along with errors in extreme event observations means that uncertainty quantification is essential. Addressing these concerns will enable improved flood forecasting methods and provide more accurate flood risk assessments. In this research, a new type of data-driven model, a quasi-real-time updating fuzzy neural network is developed to predict peak flow rates in urban riverine watersheds. A possibility-to-probability transformation is first used to convert observed data into fuzzy numbers. A possibility theory based training regime is them used to construct the fuzzy parameters and the outputs. A new entropy-based optimisation criterion is used to train the network. Two existing methods to select the optimum input parameters are modified to account for fuzzy number inputs, and compared. These methods are: Entropy-Wavelet-based Artificial Neural Network (EWANN) and Combined Neural Pathway Strength Analysis (CNPSA). Finally, an automated algorithm design to select the optimum structure of the neural network is implemented. The overall impact of each component of training this network is to replace the traditional ad hoc network configuration methods, with one based on objective criteria. Ten years of data from the Bow River in Calgary, Canada (including two major floods in 2005 and 2013) are used to calibrate and test the network. The EWANN method selected lagged peak flow as a candidate input, whereas the CNPSA method selected lagged

  4. Real-time elastography with a novel quantitative technology for assessment of liver fibrosis in chronic hepatitis B

    International Nuclear Information System (INIS)

    Wang Juan; Guo Long; Shi Xiuying; Pan Wenqian; Bai Yunfei; Ai Hong

    2012-01-01

    Background: The accurate evaluation of liver fibrosis stage is important in determining the treatment strategy. The limitations of percutaneous liver biopsy as the gold standard are obvious for invasion. Real-time elastography with conventional ultrasound probes and a new quantitative technology for diffuse histological lesion is a novel approach for staging of liver fibrosis. Purpose: This study aimed to evaluate the value of real-time tissue elastography with a new quantitative technology for the assessment of liver fibrosis stage. Materials and methods: Real-time elastography was performed in 55 patients with liver fibrosis and chronic hepatitis B and in 20 healthy volunteers. Eleven parameters for every patient in colorcode image obtained from the real-time elastography were analyzed with principal components analysis. We analyzed the correlation between elasticity index and liver fibrosis stage and the accuracy of real-time elastography for liver fibrosis staging. Additionally, aspartate transaminase-to-platelet ratio index was also included in the analysis. Results: The Spearman's correlation coefficient between the elasticity index and the histologic fibrosis stage was 0.81, which is highly significant (p 0.05), respectively. Conclusions: Real-time elastography with a new quantitative technology for diffuse histological lesion is a new and promising sonography-based noninvasive method for the assessment of liver fibrosis in patients with chronic hepatitis B.

  5. Un estudio de la evolución del pensamiento matemático : el ejemplo de la conceptualización del conjunto de los números reales y de la noción de completitud en la enseñanza universitaria

    OpenAIRE

    Bergé, Analía

    2004-01-01

    En esta tesis, enmarcada dentro del campo de Didáctica de la Matemática, se estudia la evolución en la conceptualización del conjunto de los números reales por parte de los estudiantes de nivel universitario. Se toma como referencia las carreras de Licenciatura y Profesorado en Matemática de la Universidad de Buenos Aires. ¿Qué se quiere expresar con “el estudio de la evolución..."? Los alumnos establecen un primer contacto con los números reales temprano en su escolaridad. En un primer momen...

  6. An Empirical Assessment of the Real Exchange Rate and Poverty in Nigeria

    OpenAIRE

    Ben. U. Omojimite; Victor E. Oriavwote

    2012-01-01

    This paper investigated the influence of the real exchange rate on poverty within the framework of a dependent economy model. Using data covering 1980 to 2010, the result of a Vector Error Correction model (VECM) showed that the volatility of the real exchange rate has significant influence on the level of poverty in Nigeria. Thus, government policies that targets real exchange rate could play significant role in reducing the level of poverty in Nigeria, particularly if supported by basic ins...

  7. Assessing and responding in real time to online anti-vaccine sentiment during a flu pandemic.

    Science.gov (United States)

    Seeman, Neil; Ing, Alton; Rizo, Carlos

    2010-01-01

    The perceived safety of vaccination is an important explanatory factor for vaccine uptake and, consequently, for rates of illness and death. The objectives of this study were (1) to evaluate Canadian attitudes around the safety of the H1N1 vaccine during the fall 2009 influenza pandemic and (2) to consider how public health communications can leverage the Internet to counteract, in real time, anti-vaccine sentiment. We surveyed a random sample of 175,257 Canadian web users from October 27 to November 19, 2009, about their perceptions of the safety of the HINI vaccine. In an independent analysis, we also assessed the popularity of online flu vaccine-related information using a tool developed for this purpose. A total of 27,382 unique online participants answered the survey (15.6% response rate). Of the respondents, 23.4% considered the vaccine safe, 41.4% thought it was unsafe and 35.2% reported ambivalence over its safety. Websites and blog posts with anti-vaccine sentiment remained popular during the course of the pandemic. Current public health communication and education strategies about the flu vaccine can be complemented by web analytics that identify, track and neutralize anti-vaccine sentiment on the Internet, thus increasing perceived vaccine safety. Counter-marketing strategies can be transparent and collaborative, engaging online "influencers" who spread misinformation.

  8. Real time analysis for atmospheric dispersions for Fukushima nuclear accident: Mobile phone based cloud computing assessment

    International Nuclear Information System (INIS)

    Woo, Tae Ho

    2014-01-01

    Highlights: • Possible nuclear accident is simulated for the atmospheric contaminations. • The simulations results give the relative importance of the fallouts. • The cloud computing of IT is performed successfully. • One can prepare for the possible damages of such a NPP accident. • Some other variables can be considered in the modeling. - Abstract: The radioactive material dispersion is investigated by the system dynamics (SD) method. The non-linear complex algorithm could give the information about the hazardous material behavior in the case of nuclear accident. The prevailing westerlies region is modeled for the dynamical consequences of the Fukushima nuclear accident. The event sequence shows the scenario from earthquake to dispersion of the radionuclides. Then, the dispersion reaches two cities in Korea. The importance of the radioactive dispersion is related to the fast and reliable data processing, which could be accomplished by cloud computing concept. The values of multiplications for the wind, plume concentrations, and cloud computing factor are obtained. The highest value is 94.13 in the 206th day for Seoul. In Pusan, the highest value is 15.48 in the 219th day. The source is obtained as dispersion of radionuclide multiplied by 100. The real time safety assessment is accomplished by mobile phone

  9. A real-time, quantitative PCR protocol for assessing the relative parasitemia of Leucocytozoon in waterfowl

    Science.gov (United States)

    Smith, Matthew M.; Schmutz, Joel A.; Apelgren, Chloe; Ramey, Andy M.

    2015-01-01

    Microscopic examination of blood smears can be effective at diagnosing and quantifying hematozoa infections. However, this method requires highly trained observers, is time consuming, and may be inaccurate for detection of infections at low levels of parasitemia. To develop a molecular methodology for identifying and quantifying Leucocytozoon parasite infection in wild waterfowl (Anseriformes), we designed a real-time, quantitative PCR protocol to amplify Leucocytozoon mitochondrial DNA using TaqMan fluorogenic probes and validated our methodology using blood samples collected from waterfowl in interior Alaska during late summer and autumn (n = 105). By comparing our qPCR results to those derived from a widely used nested PCR protocol, we determined that our assay showed high levels of sensitivity (91%) and specificity (100%) in detecting Leucocytozoon DNA from host blood samples. Additionally, results of a linear regression revealed significant correlation between the raw measure of parasitemia produced by our qPCR assay (Ct values) and numbers of parasites observed on blood smears (R2 = 0.694, P = 0.003), indicating that our assay can reliably determine the relative parasitemia levels among samples. This methodology provides a powerful new tool for studies assessing effects of haemosporidian infection in wild avian species.

  10. Assessment of the real-time PCR and different digital PCR platforms for DNA quantification.

    Science.gov (United States)

    Pavšič, Jernej; Žel, Jana; Milavec, Mojca

    2016-01-01

    Digital PCR (dPCR) is beginning to supersede real-time PCR (qPCR) for quantification of nucleic acids in many different applications. Several analytical properties of the two most commonly used dPCR platforms, namely the QX100 system (Bio-Rad) and the 12.765 array of the Biomark system (Fluidigm), have already been evaluated and compared with those of qPCR. However, to the best of our knowledge, direct comparison between the three of these platforms using the same DNA material has not been done, and the 37 K array on the Biomark system has also not been evaluated in terms of linearity, analytical sensitivity and limit of quantification. Here, a first assessment of qPCR, the QX100 system and both arrays of the Biomark system was performed with plasmid and genomic DNA from human cytomegalovirus. With use of PCR components that alter the efficiency of qPCR, each dPCR platform demonstrated consistent copy-number estimations, which indicates the high resilience of dPCR. Two approaches, one considering the total reaction volume and the other considering the effective reaction size, were used to assess linearity, analytical sensitivity and variability. When the total reaction volume was considered, the best performance was observed with qPCR, followed by the QX100 system and the Biomark system. In contrast, when the effective reaction size was considered, all three platforms showed almost equal limits of detection and variability. Although dPCR might not always be more appropriate than qPCR for quantification of low copy numbers, dPCR is a suitable method for robust and reproducible quantification of viral DNA, and a promising technology for the higher-order reference measurement method.

  11. Measuring everyday functional competence using the Rasch assessment of everyday activity limitations (REAL) item bank.

    Science.gov (United States)

    Oude Voshaar, Martijn A H; Ten Klooster, Peter M; Vonkeman, Harald E; van de Laar, Mart A F J

    2017-11-01

    Traditional patient-reported physical function instruments often poorly differentiate patients with mild-to-moderate disability. We describe the development and psychometric evaluation of a generic item bank for measuring everyday activity limitations in outpatient populations. Seventy-two items generated from patient interviews and mapped to the International Classification of Functioning, Disability and Health (ICF) domestic life chapter were administered to 1128 adults representative of the Dutch population. The partial credit model was fitted to the item responses and evaluated with respect to its assumptions, model fit, and differential item functioning (DIF). Measurement performance of a computerized adaptive testing (CAT) algorithm was compared with the SF-36 physical functioning scale (PF-10). A final bank of 41 items was developed. All items demonstrated acceptable fit to the partial credit model and measurement invariance across age, sex, and educational level. Five- and ten-item CAT simulations were shown to have high measurement precision, which exceeded that of SF-36 physical functioning scale across the physical function continuum. Floor effects were absent for a 10-item empirical CAT simulation, and ceiling effects were low (13.5%) compared with SF-36 physical functioning (38.1%). CAT also discriminated better than SF-36 physical functioning between age groups, number of chronic conditions, and respondents with or without rheumatic conditions. The Rasch assessment of everyday activity limitations (REAL) item bank will hopefully prove a useful instrument for assessing everyday activity limitations. T-scores obtained using derived measures can be used to benchmark physical function outcomes against the general Dutch adult population.

  12. Real-time 3D radiation risk assessment supporting simulation of work in nuclear environments

    International Nuclear Information System (INIS)

    Szoke, I; Louka, M N; Bryntesen, T R; Bratteli, J; Edvardsen, S T; RøEitrheim, K K; Bodor, K

    2014-01-01

    This paper describes the latest developments at the Institute for Energy Technology (IFE) in Norway, in the field of real-time 3D (three-dimensional) radiation risk assessment for the support of work simulation in nuclear environments. 3D computer simulation can greatly facilitate efficient work planning, briefing, and training of workers. It can also support communication within and between work teams, and with advisors, regulators, the media and public, at all the stages of a nuclear installation’s lifecycle. Furthermore, it is also a beneficial tool for reviewing current work practices in order to identify possible gaps in procedures, as well as to support the updating of international recommendations, dissemination of experience, and education of the current and future generation of workers. IFE has been involved in research and development into the application of 3D computer simulation and virtual reality (VR) technology to support work in radiological environments in the nuclear sector since the mid 1990s. During this process, two significant software tools have been developed, the VRdose system and the Halden Planner, and a number of publications have been produced to contribute to improving the safety culture in the nuclear industry. This paper describes the radiation risk assessment techniques applied in earlier versions of the VRdose system and the Halden Planner, for visualising radiation fields and calculating dose, and presents new developments towards implementing a flexible and up-to-date dosimetric package in these 3D software tools, based on new developments in the field of radiation protection. The latest versions of these 3D tools are capable of more accurate risk estimation, permit more flexibility via a range of user choices, and are applicable to a wider range of irradiation situations than their predecessors. (paper)

  13. Real-time 3D radiation risk assessment supporting simulation of work in nuclear environments.

    Science.gov (United States)

    Szőke, I; Louka, M N; Bryntesen, T R; Bratteli, J; Edvardsen, S T; RøEitrheim, K K; Bodor, K

    2014-06-01

    This paper describes the latest developments at the Institute for Energy Technology (IFE) in Norway, in the field of real-time 3D (three-dimensional) radiation risk assessment for the support of work simulation in nuclear environments. 3D computer simulation can greatly facilitate efficient work planning, briefing, and training of workers. It can also support communication within and between work teams, and with advisors, regulators, the media and public, at all the stages of a nuclear installation's lifecycle. Furthermore, it is also a beneficial tool for reviewing current work practices in order to identify possible gaps in procedures, as well as to support the updating of international recommendations, dissemination of experience, and education of the current and future generation of workers.IFE has been involved in research and development into the application of 3D computer simulation and virtual reality (VR) technology to support work in radiological environments in the nuclear sector since the mid 1990s. During this process, two significant software tools have been developed, the VRdose system and the Halden Planner, and a number of publications have been produced to contribute to improving the safety culture in the nuclear industry.This paper describes the radiation risk assessment techniques applied in earlier versions of the VRdose system and the Halden Planner, for visualising radiation fields and calculating dose, and presents new developments towards implementing a flexible and up-to-date dosimetric package in these 3D software tools, based on new developments in the field of radiation protection. The latest versions of these 3D tools are capable of more accurate risk estimation, permit more flexibility via a range of user choices, and are applicable to a wider range of irradiation situations than their predecessors.

  14. Soil Properties Database of Spanish Soils. Volume VIII.- Castilla-La Mancha (a): Toledo and Ciudad Real; Bade de Datos de Propiedades Edafologicas de los Suelos Espanoles. Volumen VIII.- Castilla-La Mancha (a): Toledo y Ciudad Real

    Energy Technology Data Exchange (ETDEWEB)

    Trueba, C.; Millan, R.; Schmid, T.; Lago, C. [CIEMAT. Madrid (Spain); Roquero, C.; Magister, M. [UPM. Madrid (Spain)

    1999-06-01

    The soil vulnerability determines the sensitivity of the soil after an accidental radioactive contamination due to Cs-137 and Sr-90. The Departamento de Impacto Ambiental de la Energia of CIEMAT is carrying out an assessment of the radiological vulnerability of the different Spanish soils found on the Iberian Peninsula. This requires the knowledge of the soil properties for the various types of existing soils. In order to achieve thin aim, a bibliographical compilation of soil profiles has been made to characterize the different soil types and create a database of their properties. Depending on the year of publication and the type of documentary source, the information compiled from the available bibliography is very heterogeneous. Therefore, an important effort has been made to normalize and process the information prior ot its incorporation to the database. This volume presents the criteria applied to normalize and process the data as well as the soil properties of the various soil types belonging to the provinces of Toledo and Ciudad Real of the Comunidad Autonoma de Castilla-La Mancha. (Author) 32 refs.

  15. Advances in real-time technology assessment and emergency response: Close-in atmospheric dispersion modeling and exposure estimation

    International Nuclear Information System (INIS)

    Sims, J.; Lee, R.; McCallen, R.; Lawver, B.; Clark, J.; Rueppel, D.; Sullivan, T.

    1992-07-01

    We have developed a stand-alone, real-time emergency response system to assess and predict the offsite dispersion of particulate releases. We have also developed advanced modeling tools that win expand the capability of the emergency response system to predict nearfield dispersion over complex terrain and around buildings

  16. The Madrid Royal Schools of St. Elisabeth and Loreto according Constitutions of 1715 and 1718 Los Reales Colegios de Santa Isabel y Loreto de Madrid según sus constituciones de 1715 y 1718

    Directory of Open Access Journals (Sweden)

    Beatriz COMELLA GUTIÉRREZ

    2013-02-01

    Full Text Available The Madrid Royal Schools of Saint Elizabeth and Loreto were founded by Philip II at the end of 16th Century. Both institutions provided education for orphan girls. They still exist as Catholic coeducational schools granted by the Education Department. These two Schools were Royal Sponsorship belonging to Palace ecclesiastical jurisdiction. The Schools Constitutions sanctioned by Philip V have been preserved until now. Although these Schools have a parallel history, the mentioned Constitutions are completely different for each School. According to these Norms, the Madrid Royal Schools of Saint Elizabeth and Loreto have many differences between them.Los Reales Colegios de Santa Isabel y Loreto de Madrid para niñas huérfanas fueron fundados por Felipe II a finales del siglo XVI. Ambas instituciones siguen funcionando en la actualidad como centros educativos católicos mixtos y concertados. Los dos fueron patronatos reales pertenecientes a la jurisdicción eclesiástica de Palacio. Se han conservado las Constituciones de ambos aprobadas bajo el reinado de Felipe V. Aunque los Colegios tienen una historia paralela, la citada normativa es muy diferente para cada institución; según las Constituciones, Santa Isabel y Loreto tienen más aspectos diferenciadores que comunes.

  17. Performance assessment of refractory samples in the Los Alamos Controlled Air Incinerator

    International Nuclear Information System (INIS)

    Hutchins, D.A.; Borduin, L.C.; Koenig, R.A.; Vavruska, J.S.; Warner, C.L.

    1986-01-01

    A refractory evaluation project was initiated in 1979 to study the performance of six selected refractory materials within the Los Alamos Controlled Air Incinerator (CAI). Determining refractory resistance to thermal shock, chemical attack, and plutonium uptake was of particular interest. The experimental refractories were subjected to a variety of waste materials, including transuranic (TRU) contaminated wastes, highly chlorinated compounds and alkaline metal salts of perchlorate, chlorate, nitrate and oxylate, over the six year period of this study. Results of this study to date indicate that the use of high alumina, and possibly specialty plastic refractories, is advisable for the lining of incinerators used for the thermal destruction of diverse chemical compounds. 12 refs., 4 tabs

  18. Enhancement of the basic seismic assessment of the Los Alamos National Laboratory facilities and buildings

    International Nuclear Information System (INIS)

    Fritz-de la Orta, G.O.

    1995-01-01

    This paper presents the results of a comparison of values obtained for the seismic security of 479 buildings and facilities at Los Alamos National Laboratory following the methodology adapted from Dr. Otto Frit's original System, and the requirements contained both in FEMA-154 ''Rapid Visual Screening of Buildings for Potential Hazards: A Handbook'' and FEMA-187 ''NEHRP Handbook for the Seismic Evaluation of Existing Buildings.'' These comparisons were made from five buildings chosen randomly illustrating a wide variety of construction types and building configurations. Each building is divided into sectors, defined as portions of it that are attached additions to the original building, or portions separated by an expansion joint between the structural systems. The five buildings studied contain a total of sixteen sectors. The paper is divided into the following sections: Introduction; Basic Concepts of the LANL Methodology; Basic Concepts of FEMA-178; Highlights of the Comparison; Comments on the Results; and Final Words

  19. Real-time measurements of secondary organic aerosol formation and aging from ambient air in an oxidation flow reactor in the Los Angeles area

    Directory of Open Access Journals (Sweden)

    A. M. Ortega

    2016-06-01

    Full Text Available Field studies in polluted areas over the last decade have observed large formation of secondary organic aerosol (SOA that is often poorly captured by models. The study of SOA formation using ambient data is often confounded by the effects of advection, vertical mixing, emissions, and variable degrees of photochemical aging. An oxidation flow reactor (OFR was deployed to study SOA formation in real-time during the California Research at the Nexus of Air Quality and Climate Change (CalNex campaign in Pasadena, CA, in 2010. A high-resolution aerosol mass spectrometer (AMS and a scanning mobility particle sizer (SMPS alternated sampling ambient and reactor-aged air. The reactor produced OH concentrations up to 4 orders of magnitude higher than in ambient air. OH radical concentration was continuously stepped, achieving equivalent atmospheric aging of 0.8 days–6.4 weeks in 3 min of processing every 2 h. Enhancement of organic aerosol (OA from aging showed a maximum net SOA production between 0.8–6 days of aging with net OA mass loss beyond 2 weeks. Reactor SOA mass peaked at night, in the absence of ambient photochemistry and correlated with trimethylbenzene concentrations. Reactor SOA formation was inversely correlated with ambient SOA and Ox, which along with the short-lived volatile organic compound correlation, indicates the importance of very reactive (τOH  ∼  0.3 day SOA precursors (most likely semivolatile and intermediate volatility species, S/IVOCs in the Greater Los Angeles Area. Evolution of the elemental composition in the reactor was similar to trends observed in the atmosphere (O : C vs. H : C slope  ∼  −0.65. Oxidation state of carbon (OSc in reactor SOA increased steeply with age and remained elevated (OSC  ∼  2 at the highest photochemical ages probed. The ratio of OA in the reactor output to excess CO (ΔCO, ambient CO above regional background vs. photochemical age is similar to

  20. Real-time measurements of secondary organic aerosol formation and aging from ambient air in an oxidation flow reactor in the Los Angeles area

    Science.gov (United States)

    Ortega, Amber M.; Hayes, Patrick L.; Peng, Zhe; Palm, Brett B.; Hu, Weiwei; Day, Douglas A.; Li, Rui; Cubison, Michael J.; Brune, William H.; Graus, Martin; Warneke, Carsten; Gilman, Jessica B.; Kuster, William C.; de Gouw, Joost; Gutiérrez-Montes, Cándido; Jimenez, Jose L.

    2016-06-01

    Field studies in polluted areas over the last decade have observed large formation of secondary organic aerosol (SOA) that is often poorly captured by models. The study of SOA formation using ambient data is often confounded by the effects of advection, vertical mixing, emissions, and variable degrees of photochemical aging. An oxidation flow reactor (OFR) was deployed to study SOA formation in real-time during the California Research at the Nexus of Air Quality and Climate Change (CalNex) campaign in Pasadena, CA, in 2010. A high-resolution aerosol mass spectrometer (AMS) and a scanning mobility particle sizer (SMPS) alternated sampling ambient and reactor-aged air. The reactor produced OH concentrations up to 4 orders of magnitude higher than in ambient air. OH radical concentration was continuously stepped, achieving equivalent atmospheric aging of 0.8 days-6.4 weeks in 3 min of processing every 2 h. Enhancement of organic aerosol (OA) from aging showed a maximum net SOA production between 0.8-6 days of aging with net OA mass loss beyond 2 weeks. Reactor SOA mass peaked at night, in the absence of ambient photochemistry and correlated with trimethylbenzene concentrations. Reactor SOA formation was inversely correlated with ambient SOA and Ox, which along with the short-lived volatile organic compound correlation, indicates the importance of very reactive (τOH ˜ 0.3 day) SOA precursors (most likely semivolatile and intermediate volatility species, S/IVOCs) in the Greater Los Angeles Area. Evolution of the elemental composition in the reactor was similar to trends observed in the atmosphere (O : C vs. H : C slope ˜ -0.65). Oxidation state of carbon (OSc) in reactor SOA increased steeply with age and remained elevated (OSC ˜ 2) at the highest photochemical ages probed. The ratio of OA in the reactor output to excess CO (ΔCO, ambient CO above regional background) vs. photochemical age is similar to previous studies at low to moderate ages and also extends to

  1. Differences between clinical "snap-shot" and "real-life" assessments of lumbar spine alignment and motion - What is the "real" lumbar lordosis of a human being?

    Science.gov (United States)

    Dreischarf, Marcel; Pries, Esther; Bashkuev, Maxim; Putzier, Michael; Schmidt, Hendrik

    2016-03-21

    The individual lumbar lordosis and lumbar motion have been identified to play an important role in pathogenesis of low back pain and are essential references for preoperative planning and postoperative evaluation. The clinical "gold-standard" for measuring lumbar lordosis and its motion are radiological "snap-shots" taken while standing and during upper-body flexion and extension. The extent to which these clinically assessed values characterise lumbar alignment and its motion in daily life merits discussion. A non-invasive measurement-system was employed to measure lumbar lordosis and lumbar motion in 208 volunteers (age: 20-74yrs; ♀/♂: 115/93). For an initial short-term measurement, comparable with the clinical "snap-shot", lumbar lordosis and its motion were assessed while standing and during flexion and extension. Subsequently, volunteers were released to their daily lives while wearing the device, and measurements were performed during the following 24h. The average lumbar lordosis during 24h (8.0°) differed significantly from the standardised measurement while standing (33.3°). Ranges of motion were significantly different throughout the day compared to standing measurements. The influence of the factors age and gender on lordosis and its motion resulted in conflicting results between long- and short-term-measurements. In conclusion, results of short-term examinations differ considerably from the average values during real-life. These findings might be important for surgical planning and increase the awareness of the biomechanical challenges that spinal structures and implants face in real-life. Furthermore, long-term assessments of spinal alignment and motion during daily life can provide valid data on spinal function and can reveal the importance of influential factors. Copyright © 2016 Elsevier Ltd. All rights reserved.

  2. A Real-Time Safety and Quality Reporting System: Assessment of Clinical Data and Staff Participation

    International Nuclear Information System (INIS)

    Rahn, Douglas A.; Kim, Gwe-Ya; Mundt, Arno J.; Pawlicki, Todd

    2014-01-01

    Purpose: To report on the use of an incident learning system in a radiation oncology clinic, along with a review of staff participation. Methods and Materials: On September 24, 2010, our department initiated an online real-time voluntary reporting system for safety issues, called the Radiation Oncology Quality Reporting System (ROQRS). We reviewed these reports from the program's inception through January 18, 2013 (2 years, 3 months, 25 days) to assess error reports (defined as both near-misses and incidents of inaccurate treatment). Results: During the study interval, there were 60,168 fractions of external beam radiation therapy and 955 brachytherapy procedures. There were 298 entries in the ROQRS system, among which 108 errors were reported. There were 31 patients with near-misses reported and 27 patients with incidents of inaccurate treatment reported. These incidents of inaccurate treatment occurred in 68 total treatment fractions (0.11% of treatments delivered during the study interval). None of these incidents of inaccurate treatment resulted in deviation from the prescription by 5% or more. A solution to the errors was documented in ROQRS in 65% of the cases. Errors occurred as repeated errors in 22% of the cases. A disproportionate number of the incidents of inaccurate treatment were due to improper patient setup at the linear accelerator (P<.001). Physician participation in ROQRS was nonexistent initially, but improved after an education program. Conclusions: Incident learning systems are a useful and practical means of improving safety and quality in patient care

  3. A Real-Time Safety and Quality Reporting System: Assessment of Clinical Data and Staff Participation

    Energy Technology Data Exchange (ETDEWEB)

    Rahn, Douglas A.; Kim, Gwe-Ya; Mundt, Arno J.; Pawlicki, Todd, E-mail: tpawlicki@ucsd.edu

    2014-12-01

    Purpose: To report on the use of an incident learning system in a radiation oncology clinic, along with a review of staff participation. Methods and Materials: On September 24, 2010, our department initiated an online real-time voluntary reporting system for safety issues, called the Radiation Oncology Quality Reporting System (ROQRS). We reviewed these reports from the program's inception through January 18, 2013 (2 years, 3 months, 25 days) to assess error reports (defined as both near-misses and incidents of inaccurate treatment). Results: During the study interval, there were 60,168 fractions of external beam radiation therapy and 955 brachytherapy procedures. There were 298 entries in the ROQRS system, among which 108 errors were reported. There were 31 patients with near-misses reported and 27 patients with incidents of inaccurate treatment reported. These incidents of inaccurate treatment occurred in 68 total treatment fractions (0.11% of treatments delivered during the study interval). None of these incidents of inaccurate treatment resulted in deviation from the prescription by 5% or more. A solution to the errors was documented in ROQRS in 65% of the cases. Errors occurred as repeated errors in 22% of the cases. A disproportionate number of the incidents of inaccurate treatment were due to improper patient setup at the linear accelerator (P<.001). Physician participation in ROQRS was nonexistent initially, but improved after an education program. Conclusions: Incident learning systems are a useful and practical means of improving safety and quality in patient care.

  4. Análisis de las tendencias macroestructurales de la lengua española en los cibermedios: las entrevistas corales de Marca.com protagonizadas por los clásicos entre el Real Madrid C. F. y el Barcelona F. C. (2010-2011

    Directory of Open Access Journals (Sweden)

    Daniel Barredo Ibáñez

    2013-01-01

    Full Text Available En este artículo se realiza un análisis lingüístico de las entrevistas corales en Marca.com en el marco de los cinco enfrentamientos deportivos entre el Real Madrid F. C. y el F. C. Barcelona (2010-2011, es decir, aquellas formas de intercambio que tuvieron como protagonista este importante evento futbolístico, denominado como ‘el Clásico’. Los resultados obtenidos muestran las tendencias macroestructurales del uso del lenguaje por parte de los usuarios o ideantes. En primer lugar, se concluye cierta despreocupación por el uso del lenguaje basado en las normas ortográficas o en las reglas sintácticas; y, en segundo lugar, una tendencia a evitar en gran medida las deformaciones lingüísticas vinculadas con los chats. Esto podría identificarse como una conciencia colectiva informativa, porque los ideantes saben que sus textos pasarán de lo íntimo a lo publicado, y de lo publicado a lo público.

  5. Real-time risk assessment in seismic early warning and rapid response: a feasibility study in Bishkek (Kyrgyzstan)

    Science.gov (United States)

    Picozzi, M.; Bindi, D.; Pittore, M.; Kieling, K.; Parolai, S.

    2013-04-01

    Earthquake early warning systems (EEWS) are considered to be an effective, pragmatic, and viable tool for seismic risk reduction in cities. While standard EEWS approaches focus on the real-time estimation of an earthquake's location and magnitude, innovative developments in EEWS include the capacity for the rapid assessment of damage. Clearly, for all public authorities that are engaged in coordinating emergency activities during and soon after earthquakes, real-time information about the potential damage distribution within a city is invaluable. In this work, we present a first attempt to design an early warning and rapid response procedure for real-time risk assessment. In particular, the procedure uses typical real-time information (i.e., P-wave arrival times and early waveforms) derived from a regional seismic network for locating and evaluating the size of an earthquake, information which in turn is exploited for extracting a risk map representing the potential distribution of damage from a dataset of predicted scenarios compiled for the target city. A feasibility study of the procedure is presented for the city of Bishkek, the capital of Kyrgyzstan, which is surrounded by the Kyrgyz seismic network by mimicking the ground motion associated with two historical events that occurred close to Bishkek, namely the 1911 Kemin ( M = 8.2; ±0.2) and the 1885 Belovodsk ( M = 6.9; ±0.5) earthquakes. Various methodologies from previous studies were considered when planning the implementation of the early warning and rapid response procedure for real-time risk assessment: the Satriano et al. (Bull Seismol Soc Am 98(3):1482-1494, 2008) approach to real-time earthquake location; the Caprio et al. (Geophys Res Lett 38:L02301, 2011) approach for estimating moment magnitude in real time; the EXSIM method for ground motion simulation (Motazedian and Atkinson, Bull Seismol Soc Am 95:995-1010, 2005); the Sokolov (Earthquake Spectra 161: 679-694, 2002) approach for estimating

  6. Los inicios de la enseñanza de las lenguas para fines específicos en el Real Colegio de Cirugía de la Armada de Cádiz

    Directory of Open Access Journals (Sweden)

    Manuel Botella Rodríguez

    2007-10-01

    Full Text Available En 1748 se funda en Cádiz (España el Real Colegio de Cirugía de la Armada. Uno de los legados más importantes que se conservan de aquella fundación es su valioso catálogo bibliográfico humanístico y científico. Hemos analizado diccionarios y manuales de gramática destinados al aprendizaje de lenguas extranjeras (fundamentalmente francés e inglés con el fin de llevar a cabo un estudio y recrear lo que pudo ser el método de adquisición de lenguas durante los siglos XVIII y XIX y encontrar un posible embrión del aprendizaje de lenguas para fines específicos en la Universidad de Cádiz.

  7. An Unobtrusive System to Measure, Assess, and Predict Cognitive Workload in Real-World Environments

    Science.gov (United States)

    Bracken, Bethany K.; Palmon, Noa; Elkin-Frankston, Seth; Irvin, Scott; Jenkins, Michael; Farry, Mike

    2017-01-01

    , designed to operate in real-world environments to be worn comfortably (e.g., positioned into a baseball cap or a surgeons cap) to measure changes in brain blood oxygenation without adding burden to the individual being assessed.

  8. Los inicios de la transición política al socialismo en Cuba. El dilema entre el poder formal y el real

    OpenAIRE

    Rafuls Pineda, Daniel

    2015-01-01

    Revisión crítica de algunas de las tesis más difundidas sobre los inicios de la transición política al socialismo en Cuba, enarboladas a partir de postulados esenciales de Marx, Engels y Lenin para explicar otros contextos históricos, que, potencialmente, pudieran contribuir a una mejor comprensión de los actuales procesos revolucionarios latinoamericanos, utilizando el propio instrumental teórico-metodológico que hemos heredado del marxismo. Critical review of some of the most widespread ...

  9. Preliminary Risk Assessment of the Southwestern Willow Flycatcher (Empidonax traillii extimus) at the Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Gallegos, A.F.; Gonzales, G.J.; Bennett, K.D.; Mullen, M.A.; Foxx, T.S.

    1998-01-01

    The southwestern willow flycatcher (Empidonax traillii extimus) is the fourth threatened or endangered species to undergo a preliminary assessment for estimating potential risk from environmental contaminants at the Los Alamos National Laboratory. The assessments are being conducted as part of a three-year project to develop a habitat management plan for threatened and endangered species and species of concern at the Laboratory. For the preliminary assessment, estimated doses were compared against toxicity reference values to generate hazard indices (HIs). This assessment included a measure of cumulative effects from multiple contaminants (radionuclides, metals, and organic chemicals) to 100 simulated nest sites located within flycatcher potential habitat. Sources of contaminant values were 10,000-ft 2 grid cells within an Ecological Exposure Unit (EEU). This EEU was estimated around the potential habitat and was based on the maximum home range for the fly catcher identified in the scientific literature. The tools used included a custom FORTRAN program, ECORSK5, and a geographic information system. Food consumption and soil ingestion contaminant pathways were addressed in the assessment. Using a four-category risk evaluation, HI results indicate no appreciable impact is expected to the southwestern willow flycatcher. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, flycatcher habitat, facility siting, and/or facility operations in order to maintain low levels of risk from contaminants

  10. Preliminary Risk Assessment of the Southwestern Willow Flycatcher (Empidonax traillii extimus) at the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Gallegos, A.F.; Gonzales, G.J.; Bennett, K.D.; Mullen, M.A.; Foxx, T.S.

    1998-10-01

    The southwestern willow flycatcher (Empidonax traillii extimus) is the fourth threatened or endangered species to undergo a preliminary assessment for estimating potential risk from environmental contaminants at the Los Alamos National Laboratory. The assessments are being conducted as part of a three-year project to develop a habitat management plan for threatened and endangered species and species of concern at the Laboratory. For the preliminary assessment, estimated doses were compared against toxicity reference values to generate hazard indices (HIs). This assessment included a measure of cumulative effects from multiple contaminants (radionuclides, metals, and organic chemicals) to 100 simulated nest sites located within flycatcher potential habitat. Sources of contaminant values were 10,000-ft{sup 2} grid cells within an Ecological Exposure Unit (EEU). This EEU was estimated around the potential habitat and was based on the maximum home range for the fly catcher identified in the scientific literature. The tools used included a custom FORTRAN program, ECORSK5, and a geographic information system. Food consumption and soil ingestion contaminant pathways were addressed in the assessment. Using a four-category risk evaluation, HI results indicate no appreciable impact is expected to the southwestern willow flycatcher. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, flycatcher habitat, facility siting, and/or facility operations in order to maintain low levels of risk from contaminants.

  11. REAL OPTIONS ANALYSIS – ASSESSMENT METHOD OF INVESTMENT PROJECTS IN GREEN ENERGY

    Directory of Open Access Journals (Sweden)

    MAFTEI DANIEL

    2014-10-01

    Full Text Available This article highlights the importance of real options as a evaluation method of investment in green energy. Article consider several theoretical and practical approaches, the analysis based on real options by many authors who have theorized and used this method. Each approach provides a operationalisation through a steps series of specific evaluation. This paper highlights the different views: academics, financiers, managers and facilitates the access to an accurate evaluation decisions of projects.

  12. Assessment of Options for the Treatment of Nitrate Salt Wastes at Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Robinson, Bruce Alan; Funk, David John; Stevens, Patrice Ann

    2016-01-01

    This paper summarizes the methodology used to evaluate options for treatment of the remediated nitrate salt waste containers at Los Alamos National Laboratory. The method selected must enable treatment of the waste drums, which consist of a mixture of complex nitrate salts (oxidizer) improperly mixed with sWheat Scoop®1, an organic kitty litter and absorbent (fuel), in a manner that renders the waste safe, meets the specifications of waste acceptance criteria, and is suitable for transport and final disposal in the Waste Isolation Pilot Plant located in Carlsbad, New Mexico. A Core Remediation Team was responsible for comprehensively reviewing the options, ensuring a robust, defensible treatment recommendation. The evaluation process consisted of two steps. First, a prescreening process was conducted to cull the list on the basis for a decision of feasibility of certain potential options with respect to the criteria. Then, the remaining potential options were evaluated and ranked against each of the criteria in a consistent methodology. Numerical scores were established by consensus of the review team. Finally, recommendations were developed based on current information and understanding of the scientific, technical, and regulatory situation. A discussion of the preferred options and documentation of the process used to reach the recommended treatment options are presented.

  13. Options Assessment Report: Treatment of Nitrate Salt Waste at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Bruce Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Stevens, Patrice Ann [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-12-17

    This report documents the methodology used to select a method of treatment for the remediated nitrate salt (RNS) and unremediated nitrate salt (UNS) waste containers at Los Alamos National Laboratory (LANL). The method selected should treat the containerized waste in a manner that renders the waste safe and suitable for transport and final disposal in the Waste Isolation Pilot Plant (WIPP) repository, under specifications listed in the WIPP Waste Acceptance Criteria (DOE/CBFO, 2013). LANL recognizes that the results must be thoroughly vetted with the New Mexico Environment Department (NMED) and that a modification to the LANL Hazardous Waste Facility Permit is a necessary step before implementation of this or any treatment option. Likewise, facility readiness and safety basis approvals must be received from the Department of Energy (DOE). This report presents LANL’s preferred option, and the documentation of the process for reaching the recommended treatment option for RNS and UNS waste, and is presented for consideration by NMED and DOE.

  14. Options assessment report: Treatment of nitrate salt waste at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Bruce Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Stevens, Patrice Ann [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-09-16

    This report documents the methodology used to select a method of treatment for the remediated nitrate salt (RNS) and unremediated nitrate salt (UNS) waste containers at Los Alamos National Laboratory (LANL). The method selected should treat the containerized waste in a manner that renders the waste safe and suitable for transport and final disposal in the Waste Isolation Pilot Plant (WIPP) repository, under specifications listed in the WIPP Waste Acceptance Criteria (DOE/CBFO, 2013). LANL recognized that the results must be thoroughly vetted with the New Mexico Environment Department (NMED) and the a modification to the LANL Hazardous Waste Facility Permit is a necessary step before implementation of this or any treatment option. Likewise, facility readiness and safety basis approvals must be received from the Department of Energy (DOE). This report presents LANL's preferred option, and the documentation of the process for reaching the recommended treatment option for RNS and UNS waste, and is presented for consideration by NMED and DOE.

  15. Assessment of Options for the Treatment of Nitrate Salt Wastes at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, Bruce Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Funk, David John [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Stevens, Patrice Ann [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2016-03-17

    This paper summarizes the methodology used to evaluate options for treatment of the remediated nitrate salt waste containers at Los Alamos National Laboratory. The method selected must enable treatment of the waste drums, which consist of a mixture of complex nitrate salts (oxidizer) improperly mixed with sWheat Scoop®1, an organic kitty litter and absorbent (fuel), in a manner that renders the waste safe, meets the specifications of waste acceptance criteria, and is suitable for transport and final disposal in the Waste Isolation Pilot Plant located in Carlsbad, New Mexico. A Core Remediation Team was responsible for comprehensively reviewing the options, ensuring a robust, defensible treatment recommendation. The evaluation process consisted of two steps. First, a prescreening process was conducted to cull the list on the basis for a decision of feasibility of certain potential options with respect to the criteria. Then, the remaining potential options were evaluated and ranked against each of the criteria in a consistent methodology. Numerical scores were established by consensus of the review team. Finally, recommendations were developed based on current information and understanding of the scientific, technical, and regulatory situation. A discussion of the preferred options and documentation of the process used to reach the recommended treatment options are presented.

  16. Real-time Risk Assessment for Aids to Navigation Using Fuzzy-FSA on Three-Dimensional Simulation System

    Directory of Open Access Journals (Sweden)

    Jinbiao Chen

    2014-06-01

    Full Text Available The risk level of the Aids to Navigation (AtoNs can reflect the ship navigation safety level in the channel to some extent. In order to appreciate the risk level of the aids to navigation (AtoNs in a navigation channel and to provide some decision-making suggestions for the AtoNs Maintenance and Management Department, the risk assessment index system of the AtoNs was built considering the advanced experience of IALA. Under the Formal Safety Assessment frame, taking the advantages of the fuzzy comprehensive evaluation method, the fuzzy-FSA model of risk assessment for aids to navigation was established. The model was implemented for the assessment of aids to navigation in Shanghai area based on the aids to navigation three-dimensional simulation system. The real-time data were extracted from the existing information system of aids to navigation, and the real-time risk assessment for aids to navigation of the chosen channel was performed on platform of the three-dimensional simulation system, with the risk assessment software. Specifically, the deep-water channel of the Yangtze River estuary was taken as an example to illustrate the general assessment procedure. The method proposed presents practical significance and application prospect on the maintenance and management of the aids to navigation.

  17. Human Reliability in Probabilistic Safety Assessments; Fiabilidad Humana en los Analisis Probabilisticos de Seguridad

    Energy Technology Data Exchange (ETDEWEB)

    Nunez Mendez, J

    1989-07-01

    Nowadays a growing interest in environmental aspects is detected in our country. It implies an assessment of the risk involved in the industrial processes and installations in order to determine if those are into the acceptable limits. In these safety assessments, among which PSA (Probabilistic Safety Assessments), can be pointed out the role played by the human being in the system is one of the more relevant subjects (This relevance has been demonstrated in the accidents happened) . However, in Spain there aren't manuals specifically dedicated to asses the human contribution to risk in the frame of PSAs. This report aims to improve this situation providing: a) a theoretical background to help the reader in the understanding of the nature of the human error, b) a quid to carry out a Human Reliability Analysis and c) a selected overview of the techniques and methodologies currently applied in this area. (Author) 20 refs.

  18. Human Reliability in Probabilistic Safety Assessments; Fiabilidad Humana en los Analisis Probabilisticos de Seguridad

    Energy Technology Data Exchange (ETDEWEB)

    Nunez Mendez, J.

    1989-07-01

    Nowadays a growing interest in environmental aspects is detected in our country. It implies an assessment of the risk involved in the industrial processes and installations in order to determine if those are into the acceptable limits. In these safety assessments, among which PSA (Probabilistic Safety Assessments), can be pointed out the role played by the human being in the system is one of the more relevant subjects (This relevance has been demonstrated in the accidents happened) . However, in Spain there aren't manuals specifically dedicated to asses the human contribution to risk in the frame of PSAs. This report aims to improve this situation providing: a) a theoretical background to help the reader in the understanding of the nature of the human error, b) a quid to carry out a Human Reliability Analysis and c) a selected overview of the techniques and methodologies currently applied in this area. (Author) 20 refs.

  19. Real-Time Tropospheric Product Establishment and Accuracy Assessment in China

    Science.gov (United States)

    Chen, M.; Guo, J.; Wu, J.; Song, W.; Zhang, D.

    2018-04-01

    Tropospheric delay has always been an important issue in Global Navigation Satellite System (GNSS) processing. Empirical tropospheric delay models are difficult to simulate complex and volatile atmospheric environments, resulting in poor accuracy of the empirical model and difficulty in meeting precise positioning demand. In recent years, some scholars proposed to establish real-time tropospheric product by using real-time or near-real-time GNSS observations in a small region, and achieved some good results. This paper uses real-time observing data of 210 Chinese national GNSS reference stations to estimate the tropospheric delay, and establishes ZWD grid model in the country wide. In order to analyze the influence of tropospheric grid product on wide-area real-time PPP, this paper compares the method of taking ZWD grid product as a constraint with the model correction method. The results show that the ZWD grid product estimated based on the national reference stations can improve PPP accuracy and convergence speed. The accuracy in the north (N), east (E) and up (U) direction increase by 31.8 %,15.6 % and 38.3 %, respectively. As with the convergence speed, the accuracy of U direction experiences the most improvement.

  20. Probabilistic risk assessment for the Los Alamos Meson Physics Facility worst-case design-basis accident

    International Nuclear Information System (INIS)

    Sharirli, M.; Butner, J.M.; Rand, J.L.; Macek, R.J.; McKinney, S.J.; Roush, M.L.

    1992-01-01

    This paper presents results from a Los Alamos National Laboratory Engineering and Safety Analysis Group assessment of the worse-case design-basis accident associated with the Clinton P. Anderson Meson Physics Facility (LAMPF)/Weapons Neutron Research (WNR) Facility. The primary goal of the analysis was to quantify the accident sequences that result in personnel radiation exposure in the WNR Experimental Hall following the worst-case design-basis accident, a complete spill of the LAMPF accelerator 1L beam. This study also provides information regarding the roles of hardware systems and operators in these sequences, and insights regarding the areas where improvements can increase facility-operation safety. Results also include confidence ranges to incorporate combined effects of uncertainties in probability estimates and importance measures to determine how variations in individual events affect the frequencies in accident sequences

  1. Floodplain Assessment for the North Ancho Canyon Aggregate Area Cleanup in Technical Area 39 at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Hathcock, Charles Dean [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-04-26

    This floodplain assessment was prepared in accordance with 10 Code of Federal Regulations (CFR) 1022 Compliance with Floodplain and Wetland Environmental Review Requirements, which was promulgated to implement the U.S. Department of Energy (DOE) requirements under Executive Order 11988 Floodplain Management and Executive Order 11990 Wetlands Protection. According to 10 CFR 1022, a 100-year floodplain is defined as “the lowlands adjoining inland and coastal waters and relatively flat areas and flood prone areas of offshore islands.” In this action, DOE is proposing to collect soil investigation samples and remove contaminated soil within and around selected solid waste management units (SWMUs) near and within the 100-year floodplain (hereafter “floodplain”) in north Ancho Canyon at Los Alamos National Laboratory (LANL). The work is being performed to comply with corrective action requirements under the 2016 Compliance Order on Consent.

  2. Study of the feasibility of a compact gamma camera for real-time cancer assessment

    CERN Document Server

    Caballero Ontanaya, Luis

    2017-01-01

    Results from the simulations of a Compton gamma camera based on compact configuration of detectors consisting in two detection modules, each of them having two stages of high-resolution position- and energy sensitive radiation detectors operated in time-coincidence are presented. Monolithic scintillation crystals instead of pixelated crystals in order to reduce dead areas have been simulated. In order to study the system feasibility to produce real-time images, different setups are considered. Performance in terms of acquisition times have been calculated to determine the real-time capabilities and limitations of such a system.

  3. Power Quality Assessment in Real Shipboard Microgrid Systems under Unbalanced and Harmonic AC Bus Voltage

    DEFF Research Database (Denmark)

    Liu, Wenzhao; Tarasiuk, Tomasz; Gorniak, Mariusz

    2018-01-01

    were proposed and carried out in a real ship under sea-going conditions to address this problem. The ship experimental results were presented and discussed considering non-linear bow thruster load and high power ballast pump loads under unbalanced and harmonic voltage conditions. In addition......, the analysis of voltage transient dips during ballast pump starting up is presented. Further, the voltage/current distortions of working generator, bow thruster and pump loads are analyzed. The paper provides a valuable analysis for coping with PQ issues in the real ship power system....

  4. 110 kV NETWORK TECHNICAL LOSSES ASSESSMENT. REAL DISTRIBUTION SYSTEM CASE STUDY

    Directory of Open Access Journals (Sweden)

    BARBULESCU C.

    2015-06-01

    Full Text Available The paper is focusing on evaluating the technical losses within a real distribution network. The study was conducted for a distribution system operator within the Romanian Power System. The analysed area is represented by a real part of the Romanian Power System. It is modelled in a computer aided power system analysis tool. Several power system operating conditions are analysed. Power system optimization measures are provided having as a goal to reduce the technical losses' value. Values obtained based on the field measurement are compared to the ones provided by computer simulations. These conclusions are very useful for the distribution network operator.

  5. Estudio colorimétrico de los azulejos del Patio de las Doncellas del Real Alcázar de Sevilla (España*

    Directory of Open Access Journals (Sweden)

    Manuel Melgosa

    2015-05-01

    Full Text Available Se han realizado medidas colorimétricas y goniocolorimétricas de 187 azulejos de la galería baja del Patio de las Doncellas (S. xiv, que pueden agruparse en torno a 5 tonos principales: blanco, negro, azul, verde y melado. Las medidas goniocolorimétricas se muestran necesarias para caracterizar correctamente la mayoría de estas muestras, siendo insuficientes las medidas colorimétricas convencionales. Los principales cambios de color se dan al movernos desde el ángulo de –15° (próximo a la dirección de reflexión especular hasta el de +45° (dirección perpendicular a la muestra, consistiendo en un descenso de claridad (L* y un aumento de croma (C*ab. Para las muestras negras se observa además un acusado descenso del ángulo de tono (hab, así como un valor alto de 16,0 para el índice de flop en claridad. Las muestras negras y meladas tienen apariencia metalizada, con valores del índice de metalizado superiores a 5,0. Las diferencias de color entre los ángulos extremos de –15° y +110° son bastante elevadas, oscilando sus valores medios entre 4,1 (blancos y 31,2 (melados unidades CIELAB. La presente caracterización goniocolorimétrica de los azulejos del Patio de las Doncellas aporta una metodología y resultados que pueden ser útiles para los trabajos de conservadores y restauradores.

  6. Development of sustainable performance indicators to assess the benefits of real-time monitoring in mechanised underground mining

    OpenAIRE

    Govindan, Rajesh; Cao, Wenzhuo; Korre, Anna; Durucan, Sevket; Graham, Peter; Simon, Clara; Barlow, Glenn; Pemberton, Ross

    2018-01-01

    This paper presents the development and quantification of a catalogue of Sustainable Performance Indicators (SPIs) for the assessment of the benefits real-time mining can offer in small and complex mechanised underground mining operations. The SPIs investigated in detail include: ‒ grade accuracy and error of the resource model, ‒ high/low grade ore classification accuracy and error, ‒ additional high grade ore identified per unit volume, ‒ profit expected per unit volume, ‒ or...

  7. Assessment of the Real Life Exposure to 2G and 3G Base Stations Over a Day from Instantaneous Measurement

    OpenAIRE

    Mahfouz , Zaher; Gati , Azeddine; Lautru , David; Wiart , Joe; Hanna , Victor Fouad

    2011-01-01

    International audience; In this paper, the general public daily exposure to mobile telephony is investigated. The considered signals are GSM900, GSM1800, UMTS and HSDPA. The study focus on the assessment of the maximal real electric field received over the day from an instantaneous measurement performed any time during the day. An extrapolation factor is presented to extrapolate an instantaneous measurement for any signal to the maximal possible value received by this signal over the day. Thi...

  8. Evaluación de los Efectos del Dinero Endógeno en los Ciclos Reales // Evaluation of The Effects of Endogenous Money in Real Cycles // Avaliação dos Efeitos do Dinheiro Endógeno em Ciclos Reais

    Directory of Open Access Journals (Sweden)

    Nelson Manolo Chávez Muñoz

    2016-11-01

    Full Text Available El estudio analiza los efectos que existen de la endogeneidad del dinero como lo postula la escuela Post-Keynesiana en la tasa de crecimiento de países emergentes como Colombia, Chile y Argentina y de países avanzados como Reino Unido, Estados Unidos y Canadá; realizando una comparación de los resultados entre los dos grupos de países. De otra parte, se estima un modelo económico para cada grupo de países en el que los créditos domésticos y las reservas internacionales explican de manera independiente a la base monetaria, con el fin de tratar de argumentar la endogeneidad de la misma. El documento presenta una aproximación al marco teórico del tema tratado desde los planteamientos post-keynesianos, incluyendo la teoría del circuito monetario, la cual cobra importancia en este trabajo, ya que los circuitistas argumentan que el proceso de producción se expande a través el crédito bancario, que es en parte lo que se pretende demostrar. De otro lado, los modelos econométricos se estimaron utilizando la metodología de panel de datos, para los años comprendidos entre 1994 y 2011. Las estimaciones econométricas evidencian en primer lugar que la tasa de crecimiento de los dos grupos de países está explicada por la base monetaria y el multiplicador monetario de manera inelástica.; mientras que la base monetaria reacciona inelásticamente a los créditos domésticos y a las reservas internacionales en los dos grupos de países.

  9. La teoría de los valores en Miguel Reale : fundamento de su pensamiento filosófico-jurídico

    OpenAIRE

    Mateos García, María Ángeles

    1996-01-01

    La presente tesis estudia la teoría iusfilosofica de Miguel Reale en torno a una tesis principal: que su teoría del valor es el fundamento de su pensamiento filosófico-jurídico. Para demostrar este supuesto he estructurado el trabajo en 3 partes, persiguiendo dos objetivos básicos: 1.-mostrar el desarrollo y evolución del pensamiento iusfilosofico de Miguel Reale en torno a un hilo conductor: su teoría del valor. 2.-interpretar su axiología en relacion con otras explicaciones; desentrañando l...

  10. On real-time assessment of post-emergency condition existence in complex electric power systems

    Energy Technology Data Exchange (ETDEWEB)

    Tarasov, Vladimir I. [Irkutsk State Technical University 83, Lermontov Street, Irkutsk 664074 (Russian Federation)

    2008-12-15

    This paper presents two effective numerical criteria of estimating post-emergency operating conditions' non-existence in complicated electric power systems. These criteria are based on mathematic and programming tools of the regularized quadratic descent method and the regularized two-parameter minimization method. The proposed criteria can be effectively applied in calculations of real-time electric operating conditions. (author)

  11. Real-time impedance-based stability assessment of grid converter interactions

    DEFF Research Database (Denmark)

    Messo, Tuomas; Luhtala, Roni; Roinila, Tomi

    2017-01-01

    , more efficient post-fault diagnostics or to enable re-selection of control parameters. The method is implemented on a dSPACE real-time control platform and the associated Control Desk software. The paper also discusses potential limitations and suggests future improvements. A short video is available...

  12. LTE delay assessment for real-time management of future smart grids

    NARCIS (Netherlands)

    Jorguseski, L.; Zhang, H.; Chrysalos, M.; Golinski, M.; Toh, Y.

    2017-01-01

    This study investigates the feasibility of using Long Term Evolution (LTE), for the real-time state estimation of the smart grids. This enables monitoring and control of future smart grids. The smart grid state estimation requires measurement reports from different nodes in the smart grid and

  13. Teaching the Assessment of Normality Using Large Easily-Generated Real Data Sets

    Science.gov (United States)

    Kulp, Christopher W.; Sprechini, Gene D.

    2016-01-01

    A classroom activity is presented, which can be used in teaching students statistics with an easily generated, large, real world data set. The activity consists of analyzing a video recording of an object. The colour data of the recorded object can then be used as a data set to explore variation in the data using graphs including histograms,…

  14. Assessment of the strengths and weaknesses of the new Real Driving Emissions (RDE) test procedure

    NARCIS (Netherlands)

    Cuelenaere, R.F.A.; Ligterink, N.E.

    2016-01-01

    Door Dieselgate is er hernieuwde aandacht voor de luchtverontreinigende uitlaatgassen van auto’s, in het bijzonder voor de hoge NOx praktijkemissies van moderne Euro-5 en Euro-6 personenauto’s en bestelwagens. De ontwikkeling van nieuwe Europese Real Driving Emissions (RDE) wetgeving wordt gezien

  15. Healthy food choices are happy food choices : evidence from a real life sample using smartphone based assessments

    OpenAIRE

    Wahl, Deborah R.; Villinger, Karoline; König, Laura M.; Ziesemer, Katrin; Schupp, Harald T.; Renner, Britta

    2017-01-01

    Research suggests that "healthy" food choices such as eating fruits and vegetables have not only physical but also mental health benefits and might be a long-term investment in future well-being. This view contrasts with the belief that high-caloric foods taste better, make us happy, and alleviate a negative mood. To provide a more comprehensive assessment of food choice and well-being, we investigated in-the-moment eating happiness by assessing complete, real life dietary behaviour across ei...

  16. Proceedings of the IAEA consultants' meeting on the assessment of the results of the REAL-84 exercise

    International Nuclear Information System (INIS)

    Zsolnay, E.M.; Nolthenius, H.J.; Piksaikin, V.

    1987-03-01

    The document contains the proceedings of a consultants' meeting organized by the IAEA to discuss the assessment of the results of the REAL-84 exercise. The aim of the exercise is to improve the assessment of accuracies in radiation damage predictions by various laboratories using good quality input data and proper calculation methods. The emphasis lies on radiation damage to reactor pressure vessels and related nuclear technology. The purpose of the meeting was to consider the progress, the presentation of the results and their interpretation, the discussion of scientific phenomena and to suggest recommendations for future actions by the IAEA and participants

  17. Soil Monitor: an open source web application for real-time soil sealing monitoring and assessment

    Science.gov (United States)

    Langella, Giuliano; Basile, Angelo; Giannecchini, Simone; Iamarino, Michela; Munafò, Michele; Terribile, Fabio

    2016-04-01

    Soil sealing is one of the most important causes of land degradation and desertification. In Europe, soil covered by impermeable materials has increased by about 80% from the Second World War till nowadays, while population has only grown by one third. There is an increasing concern at the high political levels about the need to attenuate imperviousness itself and its effects on soil functions. European Commission promulgated a roadmap (COM(2011) 571) by which the net land take would be zero by 2050. Furthermore, European Commission also published a report in 2011 providing best practices and guidelines for limiting soil sealing and imperviousness. In this scenario, we developed an open source and an open source based Soil Sealing Geospatial Cyber Infrastructure (SS-GCI) named as "Soil Monitor". This tool merges a webGIS with parallel geospatial computation in a fast and dynamic fashion in order to provide real-time assessments of soil sealing at high spatial resolution (20 meters and below) over the whole Italy. Common open source webGIS packages are used to implement both the data management and visualization infrastructures, such as GeoServer and MapStore. The high-speed geospatial computation is ensured by a GPU parallelism using the CUDA (Computing Unified Device Architecture) framework by NVIDIA®. This kind of parallelism required the writing - from scratch - all codes needed to fulfil the geospatial computation built behind the soil sealing toolbox. The combination of GPU computing with webGIS infrastructures is relatively novel and required particular attention at the Java-CUDA programming interface. As a result, Soil Monitor is smart because it can perform very high time-consuming calculations (querying for instance an Italian administrative region as area of interest) in less than one minute. The web application is embedded in a web browser and nothing must be installed before using it. Potentially everybody can use it, but the main targets are the

  18. Particularidades de los procesos valorativos en los trastornos neuróticos Particularities of the assessing processes in the neurotic upheavals

    Directory of Open Access Journals (Sweden)

    Arturo José Sánchez Hernández

    2007-04-01

    Full Text Available El autor comienza exponiendo breves antecedentes históricos del término neurosis, y lo define conceptualmente. Continúa explicando como participan factores biológicos, psicológicos y sociales, primero en la producción de una susceptibilidad a padecer trastornos neuróticos y luego en la génesis y mantenimiento de los mismos. Argumenta que los factores analizados, cada uno de forma aislada, no garantizan el surgimiento de estas entidades nosológicas, sino que tiene que producirse una confluencia de ellos propicia para la formación y puesta en funcionamiento de estos trastornos; y generarse una causalidad recursiva o circular entre determinados elementos de esos factores que consolide el proceso. Mas adelante define el concepto de valoración. Argumenta que el paciente con trastorno neurótico presenta dificultades tanto para evaluar determinados sectores de la realidad como para corregir su error de interpretación y valorativo, así como el código sobre el cual se efectúan tales errores. Termina explicando la connotación ético moral de las alteraciones valorativas que se producen en los trastornos neuróticosThe author show brief historical antecedents about neurosis term, and expose the conceptual definition about it. Later show the participation of biological, psychological and social factors, in genesis and maintenance of neurotic disorder. Argue that analysed factors, each one isolated, are not enough to originate neurotic disorders. Is necessary the confluence of this factors, and take place the reject causality among this in order to consolidated the process. Later define the valuation concept and finish establishes that the patient whit neurotic disorders have difficult to evaluate some area of reality and to correct his interpretative and evaluative mistake, in the same way as to correct the code utilized in this mistake

  19. The TEX-I real-time expert system, applied to situation assessment for the SNR-300 reactor

    International Nuclear Information System (INIS)

    Schmal, N.; Leder, H.J.; Schade, H.J.

    1988-01-01

    Interatom, a subsidiary company of Siemens, is developing expert systems for the technical domain. These systems are operating in various industrial applications like flexible manufacturing or plant configuration, based on a domain-specific expert system shell, developed by Interatom. Additional projects are focusing on real-time diagnostics, e.g., for nuclear power plants. The authors report in this paper about a diagnosis expert system for the liquid-metal fast breeder reactor SNR-300, which uses new real-time tools, developed within the German TEX-I project (technical expert systems for data interpretation, diagnosis, and process control). The purpose of the system is to support the reactor operators in assessing plant status in real time, based on readings from many sensors. By on-line connection to the process control computer, it can monitor all incoming signal values, check the consistency of data, continuously diagnose the current plant status, detect unusual trends prior to accidents, localize faulty components, and recommended operator response in abnormal conditions. In the present knowledge acquisition and test phase, the expert system is connected to a real-time simulation of the reactor. The simulator is based on a thermohydraulic code for simulation of the transient behavior of temperatures and flow rates in the reactor core, plena, pipes, pumps, valves, intermediate heat exchangers, and cooling components. Additionally, the system's response to an asynchronous operator interaction can be simulated

  20. LA TEORÍA DEL SERVICIO PÚBLICO Y SU APLICACIÓN REAL EN MATERIA DE ACUEDUCTO DURANTE LA DÉCADA DE LOS TREINTA

    Directory of Open Access Journals (Sweden)

    Antonio Alejandro Barreto Moreno

    2011-11-01

    Full Text Available En la década de los treinta, la noción de servicio público se encuentra en el centro de una construcción jurídica sistemática del Estado; su organización tuvo como precursor a León Duguit, cuya recepción en Colombia fue de cierto impacto en la política estatal interna en la primera mitad del siglo XX. A partir de lo anterior, este escrito se propone analizar si, en la realidad de la actividad estatal y los servicios públicos en el período 1930-1940, se vieron reflejadas las ideas importadas de la escuela francesa o si, por el contrario, el influjo del que se habla fue meramente enunciativo y se quedó en la simplediscusión dogmática legal y constitucional. Este ejercicio de validación para el caso de Bogotá permite mostrar la noción de servicio público en acción, esto es,cumpliendo el objetivo de realización de la función social del Estado. Para cumplir con el objetivo propuesto, se estudian dos asuntos en la prestación del servicio público de acueducto: primero, es importante evidenciar en los antecedentes y texto definitivo de la Ley 65 de 1936 (República de Colombia, 1936A que probablemente estuvieron influenciados por la tendencia doctrinal que se viene comentando; y segundo, que algo semejante ocurrió en la prestación del servicio público en la ciudad de Bogotá para el período 1930-1940.

  1. Assessing Task Migration Impact on Embedded Soft Real-Time Streaming Multimedia Applications

    Directory of Open Access Journals (Sweden)

    Alimonda Andrea

    2008-01-01

    Full Text Available Abstract Multiprocessor systems on chips (MPSoCs are envisioned as the future of embedded platforms such as game-engines, smart-phones and palmtop computers. One of the main challenge preventing the widespread diffusion of these systems is the efficient mapping of multitask multimedia applications on processing elements. Dynamic solutions based on task migration has been recently explored to perform run-time reallocation of task to maximize performance and optimize energy consumption. Even if task migration can provide high flexibility, its overhead must be carefully evaluated when applied to soft real-time applications. In fact, these applications impose deadlines that may be missed during the migration process. In this paper we first present a middleware infrastructure supporting dynamic task allocation for NUMA architectures. Then we perform an extensive characterization of its impact on multimedia soft real-time applications using a software FM Radio benchmark.

  2. Assessing nonlinear structures in real exchange rates using recurrence plot strategies

    Science.gov (United States)

    Belaire-Franch, Jorge; Contreras, Dulce; Tordera-Lledó, Lorena

    2002-11-01

    Purchasing power parity (PPP) is an important theory at the basis of a large number of economic models. However, the implication derived from the theory that real exchange rates must follow stationary processes is not conclusively supported by empirical studies. In a recent paper, Serletis and Gogas [Appl. Finance Econ. 10 (2000) 615] show evidence of deterministic chaos in several OECD exchange rates. As a consequence, PPP rejections could be spurious. In this work, we follow a two-stage testing procedure to test for nonlinearities and chaos in real exchange rates, using a new set of techniques designed by Webber and Zbilut [J. Appl. Physiol. 76 (1994) 965], called recurrence quantification analysis (RQA). Our conclusions differ slightly from Serletis and Gogas [Appl. Finance Econ. 10 (2000) 615], but they are also supportive of chaos for some exchange rates.

  3. Assessing Task Migration Impact on Embedded Soft Real-Time Streaming Multimedia Applications

    Directory of Open Access Journals (Sweden)

    Andrea Acquaviva

    2008-01-01

    Full Text Available Multiprocessor systems on chips (MPSoCs are envisioned as the future of embedded platforms such as game-engines, smart-phones and palmtop computers. One of the main challenge preventing the widespread diffusion of these systems is the efficient mapping of multitask multimedia applications on processing elements. Dynamic solutions based on task migration has been recently explored to perform run-time reallocation of task to maximize performance and optimize energy consumption. Even if task migration can provide high flexibility, its overhead must be carefully evaluated when applied to soft real-time applications. In fact, these applications impose deadlines that may be missed during the migration process. In this paper we first present a middleware infrastructure supporting dynamic task allocation for NUMA architectures. Then we perform an extensive characterization of its impact on multimedia soft real-time applications using a software FM Radio benchmark.

  4. Future teachers’ perception on the assessing systems for their learning Percepción de los futuros docentes sobre los sistemas de evaluación de sus aprendizajes

    Directory of Open Access Journals (Sweden)

    Víctor Manuel López Pator

    2012-11-01

    Full Text Available This paper is aimed at analysing the students’ perception on assessment and grading systems, instruments and techniques used in Teacher Education (TE. In order to determine the current situation for this assessment in TE a questionnaire containing four subscales was developed with a high reliability degree. Data obtained are applied to a simple of 635 students from 7 different colleges and analysed with both descriptive and inferential statistics using single-factor ANOVA. The outcomes show that assessing practices oriented towards learning are still minority practices in TE. On the other hand, the existence of so many significant differences between Primary Teacher Education and Secondary Teacher Education is worrisome. The analyses also suggest there are few subjects containing assessing styles oriented towards learning, although they include very varied and rich strategies.La finalidad de este estudio es analizar la percepción que el alumnado tiene de los sistemas, instrumentos y técnicas de evaluación y calificación que se utilizan en la formación inicial del profesorado (FIP. Para determinar la situación actual de esta evaluación en la FIP se ha elaborado un cuestionario con cuatro subescalas que ha presentado un nivel alto de fiabilidad. Los datos obtenidos, tras su aplicación a una muestra de 635 alumnos, pertenecientes a 7 centros universitarios, se analizan tanto a nivel descriptivo como inferencial utilizando ANOVAs de un factor. Los resultados indican que las prácticas de evaluación orientadas al aprendizaje son todavía minoritarias en la FIP. En cambio es preocupante la existencia de numerosas diferencias significativas entre la FIP de primaria y de secundaria. Los análisis sugieren, además, que existen pocas asignaturas con estilos de evaluación orientados al aprendizaje, pero en ellas se utilizan estrategias muy variadas y ricas.

  5. Aplicación de técnicas de PCR en tiempo real a la trazabilidad y autenticidad de los piensos

    OpenAIRE

    Pegels Rojas, Nicolette

    2015-01-01

    La trazabilidad y el correcto etiquetado de los piensos y sus ingredientes son factores esenciales para prevenir fraudes y garantizar la seguridad alimentaria. En el ámbito de la lucha contra las Encefalopatías Espongiformes Transmisibles (EETs), la prohibición de la Unión Europea (UE) de alimentar a rumiantes y otros animales de granja con harinas de carne y huesos derivadas de animales, hace necesaria la disponibilidad de metodologías que permitan identificar el origen de las materias prima...

  6. Wetland Plant Guide for Assessing Habitat Impacts of Real-Time Salinity Management

    OpenAIRE

    Quinn, Nigel W.T.; Feldmann, Sara A.

    2004-01-01

    This wetland plant guide was developed to aid moist soil plant identification and to assist in the mapping of waterfowl and shorebird habitat in the Grassland Water District and surrounding wetland areas. The motivation for this habitat mapping project was a concern that real-time salinity management of wetland drainage might have long-term consequences for wildfowl habitat health -- changes in wetland drawdown schedules might, over the long term, lead to increased soil salinity and othe...

  7. Real-Time Water Quality Monitoring and Habitat Assessment in the San Luis National Wildlife Refuge

    OpenAIRE

    Quinn, Nigel W.T.; Hanlon, Jeremy S.; Burns, Josephine R.; Stromayer, Karl A.K.; Jordan, Brandon M.; Ennis, Mike J.; Woolington, Dennis W.

    2005-01-01

    The project report describes a two year experiment to control wetland drainage to the San Joaquin River of California from the San Luis National Wildlife Refuge using a decision support system for real-time water quality management. This system required the installation and operation of one inlet and three drainage flow and water quality monitoring stations which allowed a simnple mass balance model to be developed of the seasonally managed wetlands in the study area. Remote sensing meth...

  8. Los Neutrinos Los Neutrinos

    Directory of Open Access Journals (Sweden)

    Julián Félix

    2012-02-01

    Full Text Available From all the proposals to understand the structure of matter, and the way the natural world is conformed, the one about neutrinos is the most enigmatic, abstract, and foreign to immediate experience; however, this is the one that has delved more deeply over the nearly eighty years since it was formulated by Wolfgang Pauli –in 1930- as a radical proposition to understand nucleon decay, and the decay of other particles, without the violation of the principle of conservation of energy and momentum at subatomic level. This proposition has evolved through the years, and from Pauli’s original idea only the basic elements remain.This article contains the tale of the hypothesis of neutrinos, its early history, its evolution up to present day, and the efforts done nowadays to study them. In summary, this is the physics of neutrinos. De todas las propuestas para entender la estructura de la materia, y la conformación del mundo natural, los neutrinos es la más enigmática, abstracta, y ajena a la experiencia inmediata; sin embargo, es la que más hondo ha ido calando a lo largo de los ya casi ochenta años de haber sido formulada por Wolfgang Pauli –en el año 1930- como una medida radical para entender el decaimiento de los nucleones, y otras partículas, sin que se violara el principio de la conservación de la energía y del momento a nivel subatómico. La propuesta ha evolucionado a lo largo de los años, y de la idea original de Pauli ya sólo lo básico permanece. En este artículo está el relato de la hipótesis de los neutrinos, su historia primera, su evolución hasta el presente, los esfuerzos que en la actualidad se realizan para estudiarlos. En breve, ésta es la física de los neutrinos.

  9. La Máquina. Tensión real / virtual en los modos de producción del objeto estético..

    OpenAIRE

    Maldonado Gómez, José

    2015-01-01

    [EN] Through a qualitative model I’ll try to show the structural relationships between different components and potential of the art object (yield and product) and how the objective reality of this requires a fine mesh of conceptual elements that can be considered as the virtual side of the model. The real and virtual elements are "engaged" to ensure the functioning of the model and the possible interpretations derived from its dynamic potential (transitivity). The model I intend to use will ...

  10. Utilization of real time PCR for the assessment of egg burden in the organs of Schistosoma japonicum experimentally infected mice.

    Science.gov (United States)

    Dang-Trinh, Minh-Anh; Angeles, Jose Ma M; Moendeg, Kharleezelle J; Macalanda, Adrian Miki C; Higuchi, Luna; Oto, Chiho; Kirinoki, Masashi; Chigusa, Yuichi; Kawazu, Shin-Ichiro

    2018-06-01

    Schistosoma japonicum, causing zoonotic intestinal schistosomiasis, is found in China, the Philippines and parts of Indonesia. Severe disease manifestations are basically due to the deposition of eggs in some vital organs such as the liver, spleen and brain. Traditionally, histopathological microscopic examination of the egg burden was used to evaluate the intensity of infection in the affected organs. However, this technique is laborious, time-consuming and requires trained personnel. In this study, real time PCR targeting the mitochondrial NADH dehydrogenase I gene was used to compare with microscopic examination of tissue sections in evaluating the egg burdens in different affected organs. Livers, spleens and brains of the S. japonicum infected mice after 8 and 18 weeks post-infection (p.i) were harvested and examined. Results showed that there were statistically significant correlations between the egg burden evaluated by tissue section examination, and the Ct values of the real time PCR of livers with heavy egg burden at 8 (r = -0.81) and 18 (r = -0.80) weeks p.i. Furthermore, a correlation (r = -0.56) between the egg burden assessed by the microscopic examination and Ct value of the real time PCR of spleens with moderate egg burden after 18 weeks p.i and not 8 weeks p.i was also observed. Brains with low egg burden showed no schistosome eggs in the microscopic examination, however one sample tested positive by real time PCR. These results suggested that real time PCR is useful in evaluating schistosome egg burden in the organs of the experimentally infected mice model that will give further insights into the pathology of schistosomiasis. Copyright © 2018 Elsevier Inc. All rights reserved.

  11. Assessment that Matters: Integrating the "Chore" of Department-Based Assessment with Real Improvements in Political Science Education

    Science.gov (United States)

    Deardorff, Michelle D.; Folger, Paul J.

    2005-01-01

    Assessment requirements often raise great concerns among departments and faculty: fear of loss of autonomy, distraction from primary departmental goals, and the creation of alien and artificial external standards. This article demonstrates how one political science department directly responded to their own unique circumstances in assessing their…

  12. Perils of using speed zone data to assess real-world compliance to speed limits.

    Science.gov (United States)

    Chevalier, Anna; Clarke, Elizabeth; Chevalier, Aran John; Brown, Julie; Coxon, Kristy; Ivers, Rebecca; Keay, Lisa

    2017-11-17

    Real-world driving studies, including those involving speeding alert devices and autonomous vehicles, can gauge an individual vehicle's speeding behavior by comparing measured speed with mapped speed zone data. However, there are complexities with developing and maintaining a database of mapped speed zones over a large geographic area that may lead to inaccuracies within the data set. When this approach is applied to large-scale real-world driving data or speeding alert device data to determine speeding behavior, these inaccuracies may result in invalid identification of speeding. We investigated speeding events based on service provider speed zone data. We compared service provider speed zone data (Speed Alert by Smart Car Technologies Pty Ltd., Ultimo, NSW, Australia) against a second set of speed zone data (Google Maps Application Programming Interface [API] mapped speed zones). We found a systematic error in the zones where speed limits of 50-60 km/h, typical of local roads, were allocated to high-speed motorways, which produced false speed limits in the speed zone database. The result was detection of false-positive high-range speeding. Through comparison of the service provider speed zone data against a second set of speed zone data, we were able to identify and eliminate data most affected by this systematic error, thereby establishing a data set of speeding events with a high level of sensitivity (a true positive rate of 92% or 6,412/6,960). Mapped speed zones can be a source of error in real-world driving when examining vehicle speed. We explored the types of inaccuracies found within speed zone data and recommend that a second set of speed zone data be utilized when investigating speeding behavior or developing mapped speed zone data to minimize inaccuracy in estimates of speeding.

  13. Real time assessment of RF cardiac tissue ablation with optical spectroscopy

    Energy Technology Data Exchange (ETDEWEB)

    Demos, S G; Sharareh, S

    2008-03-20

    An optical spectroscopy approach is demonstrated allowing for critical parameters during RF ablation of cardiac tissue to be evaluated in real time. The method is based on incorporating in a typical ablation catheter transmitting and receiving fibers that terminate at the tip of the catheter. By analyzing the spectral characteristics of the NIR diffusely reflected light, information is obtained on such parameters as, catheter-tissue proximity, lesion formation, depth of penetration of the lesion, formation of char during the ablation, formation of coagulum around the ablation site, differentiation of ablated from healthy tissue, and recognition of micro-bubble formation in the tissue.

  14. Assessment of offsite, real-time dose measurement systems for emergency situations

    International Nuclear Information System (INIS)

    Maeck, W.J.; Hoffman, L.G.; Staples, B.A.; Keller, J.H.

    1982-04-01

    An evaluation is made of the effectiveness of fixed, real-time monitoring systems around nuclear power stations in determining the magnitude of unmonitored releases. The effects of meteorological conditions on the accuracy with which the magnitude of unmonitored releases is determined and the uncertainties inherent in defining these meteorological conditions are discussed. The number and placement of fixed field detectors in a system is discussed, and the data processing equipment required to convert field detector output data into release rate information is described. Cost data relative to the purchase and installation of specific systems are given, as well as the characteristics and information return for a system purchased at an arbitrary cost

  15. Evaluation of enhancements to Thevenin equivalent based methods for real-time voltage stability assessment

    DEFF Research Database (Denmark)

    Perez, Angel; Jóhannsson, Hjörtur; Østergaard, Jacob

    2014-01-01

    The possibilities offered by the use of Phasor Measurement Units (PMU) in real - time monitoring provide interesting ways to ensure secure operation of power systems. This paper studies the specific case of voltage stability and the possible improvements to the Thevenin equivalent methods, which...... is applied generally with local measurements. This paper uses the PMU measurements to calculate the grid transformation coefficients to obtain wide - area information. This is achieved by studying the generator's electromo tive force estimated using values in the coefficient transformation matrix...

  16. Array-Based Ultrawideband through-Wall Radar: Prediction and Assessment of Real Radar Abilities

    Directory of Open Access Journals (Sweden)

    Nadia Maaref

    2013-01-01

    Full Text Available This paper deals with a new through-the-wall (TTW radar demonstrator for the detection and the localisation of people in a room (in a noncooperative way with the radar situated outside but in the vicinity of the first wall. After modelling the propagation through various walls and quantifying the backscattering by the human body, an analysis of the technical considerations which aims at defining the radar design is presented. Finally, an ultrawideband (UWB frequency modulated continuous wave (FMCW radar is proposed, designed, and implemented. Some representative trials show that this radar is able to localise and track moving people behind a wall in real time.

  17. Healthy food choices are happy food choices: Evidence from a real life sample using smartphone based assessments.

    Science.gov (United States)

    Wahl, Deborah R; Villinger, Karoline; König, Laura M; Ziesemer, Katrin; Schupp, Harald T; Renner, Britta

    2017-12-06

    Research suggests that "healthy" food choices such as eating fruits and vegetables have not only physical but also mental health benefits and might be a long-term investment in future well-being. This view contrasts with the belief that high-caloric foods taste better, make us happy, and alleviate a negative mood. To provide a more comprehensive assessment of food choice and well-being, we investigated in-the-moment eating happiness by assessing complete, real life dietary behaviour across eight days using smartphone-based ecological momentary assessment. Three main findings emerged: First, of 14 different main food categories, vegetables consumption contributed the largest share to eating happiness measured across eight days. Second, sweets on average provided comparable induced eating happiness to "healthy" food choices such as fruits or vegetables. Third, dinner elicited comparable eating happiness to snacking. These findings are discussed within the "food as health" and "food as well-being" perspectives on eating behaviour.

  18. Accuracy of real-time shear wave elastography for assessing liver fibrosis in chronic hepatitis C: a pilot study.

    Science.gov (United States)

    Ferraioli, Giovanna; Tinelli, Carmine; Dal Bello, Barbara; Zicchetti, Mabel; Filice, Gaetano; Filice, Carlo

    2012-12-01

    Real-time shear wave elastography (SWE) is a novel, noninvasive method to assess liver fibrosis by measuring liver stiffness. This single-center study was conducted to assess the accuracy of SWE in patients with chronic hepatitis C (CHC), in comparison with transient elastography (TE), by using liver biopsy (LB) as the reference standard. Consecutive patients with CHC scheduled for LB by referring physicians were studied. One hundred and twenty-one patients met inclusion criteria. On the same day, real-time SWE using the ultrasound (US) system, Aixplorer (SuperSonic Imagine S.A., Aix-en-Provence, France), TE using FibroScan (Echosens, Paris, France), and US-assisted LB were consecutively performed. Fibrosis was staged according to the METAVIR scoring system. Analyses of receiver operating characteristic (ROC) curve were performed to calculate optimal area under the ROC curve (AUROC) for F0-F1 versus F2-F4, F0- F2 versus F3-F4, and F0-F3 versus F4 for both real-time SWE and TE. Liver stiffness values increased in parallel with degree of liver fibrosis, both with SWE and TE. AUROCs were 0.92 (95% confidence interval [CI]: 0.85-0.96) for SWE and 0.84 (95% CI: 0.76-0.90) for TE (P = 0.002), 0.98 (95% CI: 0.94-1.00) for SWE and 0.96 (95% CI: 0.90-0.99) for TE (P = 0.14), and 0.98 (95% CI: 0.93-1.00) for SWE and 0.96 (95% CI: 0.91-0.99) for TE (P = 0.48), when comparing F0-F1 versus F2- F4, F0- F2 versus F3-F4, and F0 -F3 versus F4, respectively. The results of this study show that real-time SWE is more accurate than TE in assessing significant fibrosis (≥ F2). With respect to TE, SWE has the advantage of imaging liver stiffness in real time while guided by a B-mode image. Thus, the region of measurement can be guided with both anatomical and tissue stiffness information. Copyright © 2012 American Association for the Study of Liver Diseases.

  19. Intraoperative brain hemodynamic response assessment with real-time hyperspectral optical imaging (Conference Presentation)

    Science.gov (United States)

    Laurence, Audrey; Pichette, Julien; Angulo-Rodríguez, Leticia M.; Saint Pierre, Catherine; Lesage, Frédéric; Bouthillier, Alain; Nguyen, Dang Khoa; Leblond, Frédéric

    2016-03-01

    Following normal neuronal activity, there is an increase in cerebral blood flow and cerebral blood volume to provide oxygenated hemoglobin to active neurons. For abnormal activity such as epileptiform discharges, this hemodynamic response may be inadequate to meet the high metabolic demands. To verify this hypothesis, we developed a novel hyperspectral imaging system able to monitor real-time cortical hemodynamic changes during brain surgery. The imaging system is directly integrated into a surgical microscope, using the white-light source for illumination. A snapshot hyperspectral camera is used for detection (4x4 mosaic filter array detecting 16 wavelengths simultaneously). We present calibration experiments where phantoms made of intralipid and food dyes were imaged. Relative concentrations of three dyes were recovered at a video rate of 30 frames per second. We also present hyperspectral recordings during brain surgery of epileptic patients with concurrent electrocorticography recordings. Relative concentration maps of oxygenated and deoxygenated hemoglobin were extracted from the data, allowing real-time studies of hemodynamic changes with a good spatial resolution. Finally, we present preliminary results on phantoms obtained with an integrated spatial frequency domain imaging system to recover tissue optical properties. This additional module, used together with the hyperspectral imaging system, will allow quantification of hemoglobin concentrations maps. Our hyperspectral imaging system offers a new tool to analyze hemodynamic changes, especially in the case of epileptiform discharges. It also offers an opportunity to study brain connectivity by analyzing correlations between hemodynamic responses of different tissue regions.

  20. Real-Time Scintigraphic Assessment of Intravenous Radium-223 Administration for Quality Control

    Directory of Open Access Journals (Sweden)

    Chadwick L. Wright

    2015-01-01

    Full Text Available Radium-223 (223Ra dichloride is an approved intravenous radiotherapy for patients with osseous metastases from castration-resistant prostate cancer (CRPC. In addition to the therapeutic alpha radiation, there is additional 223Ra radiation generated which produces photons that can be imaged with conventional gamma cameras. No studies have evaluated real-time and quality imaging during intravenous 223Ra administration to verify systemic circulation and exclude 223Ra extravasation at the injection site. A retrospective review was performed for fifteen 223Ra administrations for CRPC patients which were imaged using a large field of view portable gamma camera (LFOVPGC for the purposes of quality control and patient safety. Dynamic imaging of the chest was performed before, during, and after the 223Ra administration to verify systemic circulation, per institutional clinical protocol. Before and after 223Ra administration, a static image was obtained of the intravenous access site. Dynamic imaging of the chest confirmed systemic administration early during the 1-minute injection period for all patients. There were no cases of focal 223Ra extravasation at the site of intravenous access. These results verify that systemic 223Ra administrations can be quantified with real-time imaging using an LFOVPGC. This simple approach can confirm and quantify systemic circulation of 223Ra early during injection and exclude focal extravasation for the purposes of quality control.

  1. Wetland Plant Guide for Assessing Habitat Impacts of Real-Time Salinity Management

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, Nigel W.T.; Feldmann, Sara A.

    2004-10-15

    This wetland plant guide was developed to aid moist soil plant identification and to assist in the mapping of waterfowl and shorebird habitat in the Grassland Water District and surrounding wetland areas. The motivation for this habitat mapping project was a concern that real-time salinity management of wetland drainage might have long-term consequences for wildfowl habitat health--changes in wetland drawdown schedules might, over the long term, lead to increased soil salinity and other conditions unfavorable to propagation of the most desirable moist soil plants. Hence, the implementation of a program to monitor annual changes in the most common moist soil plants might serve as an index of habitat health and sustainability. Our review of the current scientific and popular literature failed to identify a good, comprehensive field guide that could be used to calibrate and verify high resolution remote sensing imagery, that we had started to use to develop maps of wetland moist soil plants in the Grassland Water District. Since completing the guide it has been used to conduct ground truthing field surveys using the California Native Plant Society methodology in 2004. Results of this survey and a previous wetland plant survey in 2003 are published in a companion LBNL publication summarizing 4 years of fieldwork to advance the science of real-time wetland salinity management.

  2. Leveraging Educational Data Mining for Real-Time Performance Assessment of Scientific Inquiry Skills within Microworlds

    Science.gov (United States)

    Gobert, Janice D.; Sao Pedro, Michael A.; Baker, Ryan S. J. D.; Toto, Ermal; Montalvo, Orlando

    2012-01-01

    We present "Science Assistments," an interactive environment, which assesses students' inquiry skills as they engage in inquiry using science microworlds. We frame our variables, tasks, assessments, and methods of analyzing data in terms of "evidence-centered design." Specifically, we focus on the "student model," the…

  3. Real-World Assessment of Clinical Outcomes in Patients with Lower-Risk Myelofibrosis Receiving Treatment with Ruxolitinib

    Directory of Open Access Journals (Sweden)

    Keith L. Davis

    2015-01-01

    Full Text Available Few trial-based assessments of ruxolitinib in patients with lower-risk myelofibrosis (MF have been conducted, and no studies have made such assessments in a real-world population. We assessed changes in spleen size and constitutional symptoms during ruxolitinib treatment using a retrospective, observational review of anonymized US medical record data of patients diagnosed with IPSS low-risk (n=25 or intermediate-1-risk (n=83 MF. The majority of patients were male (low risk, 60%; intermediate-1 risk, 69%. Most patients (92% and 77% were still receiving ruxolitinib at the medical record abstraction date (median observation/exposure time, 8 months. The proportion of patients with moderate or severe palpable splenomegaly (≥10 cm decreased from diagnosis (56% to best response (12%. Fatigue was reported in 47% of patients and was the most common constitutional symptom. For most symptoms in both risk groups, shifts in the distribution of severity from more to less severe from diagnosis to best response were observed. Both patients with low-risk and intermediate-1-risk MF experienced a substantial decrease in spleen size with ruxolitinib treatment in real-world settings. For most symptoms examined, there were distinct improvements in the distribution of severity during ruxolitinib treatment. These findings suggest that patients with lower-risk MF may benefit clinically from ruxolitinib treatment.

  4. Los reales de minas de la caja de Guadalajara durante el siglo XVIII: Circuitos comerciales y producción de plata

    Directory of Open Access Journals (Sweden)

    de León Meza, C. René

    2011-08-01

    Full Text Available This article shows the economic significance of the group of mines that belonged to the jurisdiction of the «Caja de Guadalajara». The novelty lies in that local historiography had erroneously labeled these mining camps as being small. Recent studies show that they were not so small after all. These groups of mines were the focal point of the economy of a vast region and triggered the development of agriculture, livestock and trade activities. This article reveals the nexus between the fluctuations in silver production and events in Europe.

    Este artículo da a conocer la importancia económica que tuvo un conjunto de reales de minas que perteneció a la jurisdicción de la caja de Guadalajara. Es novedoso porque por primera vez son estudiados aquéllos que la historiografía local ha considerado erróneamente como «pequeños reales de minas». Estas explotaciones fueron el eje articulador de la economía en una vasta región que impulsó el desarrollo de la ganadería, agricultura y comercio. Vincula las fluctuaciones en la producción de plata con sucesos ocurridos en Europa.

  5. Real-Time GPS Monitoring for Earthquake Rapid Assessment in the San Francisco Bay Area

    Science.gov (United States)

    Guillemot, C.; Langbein, J. O.; Murray, J. R.

    2012-12-01

    The U.S. Geological Survey Earthquake Science Center has deployed a network of eight real-time Global Positioning System (GPS) stations in the San Francisco Bay area and is implementing software applications to continuously evaluate the status of the deformation within the network. Real-time monitoring of the station positions is expected to provide valuable information for rapidly estimating source parameters should a large earthquake occur in the San Francisco Bay area. Because earthquake response applications require robust data access, as a first step we have developed a suite of web-based applications which are now routinely used to monitor the network's operational status and data streaming performance. The web tools provide continuously updated displays of important telemetry parameters such as data latency and receive rates, as well as source voltage and temperature information within each instrument enclosure. Automated software on the backend uses the streaming performance data to mitigate the impact of outages, radio interference and bandwidth congestion on deformation monitoring operations. A separate set of software applications manages the recovery of lost data due to faulty communication links. Displacement estimates are computed in real-time for various combinations of USGS, Plate Boundary Observatory (PBO) and Bay Area Regional Deformation (BARD) network stations. We are currently comparing results from two software packages (one commercial and one open-source) used to process 1-Hz data on the fly and produce estimates of differential positions. The continuous monitoring of telemetry makes it possible to tune the network to minimize the impact of transient interruptions of the data flow, from one or more stations, on the estimated positions. Ongoing work is focused on using data streaming performance history to optimize the quality of the position, reduce drift and outliers by switching to the best set of stations within the network, and

  6. Real-time biosensor for the assessment of nanotoxicity and cancer electrotherapy

    Science.gov (United States)

    Hondroulis, Evangelia

    Knowledge of cell electronics has led to their integration to medicine either by physically interfacing electronic devices with biological systems or by using electronics for both detection and characterization of biological materials. In this dissertation, an electrical impedance sensor (EIS) was used to measure the electrode surface impedance changes from cell samples of human and environmental toxicity of nanoscale materials in 2D and 3D cell culture models. The impedimetric response of human lung fibroblasts and rainbow trout gill epithelial cells when exposed to various nanomaterials was tested to determine their kinetic effects towards the cells and to demonstrate the biosensor's ability to monitor nanotoxicity in real-time. Further, the EIS allowed rapid, real-time and multi-sample analysis creating a versatile, noninvasive tool that is able to provide quantitative information with respect to alteration in cellular function. We then extended the application of the unique capabilities of the EIS to do real-time analysis of cancer cell response to externally applied alternating electric fields at different intermediate frequencies and low-intensity. Decreases in the growth profiles of the ovarian and breast cancer cells were observed with the application of 200 and 100 kHz, respectively, indicating specific inhibitory effects on dividing cells in culture in contrast to the non-cancerous HUVECs and mammary epithelial cells. We then sought to enhance the effects of the electric field by altering the cancer cell's electronegative membrane properties with HER2 antibody functionalized nanoparticles. An Annexin V/EthD-III assay and zeta potential were performed to determine the cell death mechanism indicating apoptosis and a decrease in zeta potential with the incorporation of the nanoparticles. With more negatively charged HER2-AuNPs attached to the cancer cell membrane, the decrease in membrane potential would thus leave the cells more vulnerable to the

  7. A spatially-dynamic preliminary risk assessment of the bald eagle at the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Gonzales, G.J.; Gallegos, A.F.; Foxx, T.S.; Fresquez, P.R.; Mullen, M.A.; Pratt, L.E.; Gomez, P.E.

    1998-04-01

    The Endangered Species Act of 1973 and the Record of Decision on the Dual Axis Radiographic Hydrodynamic Test Facility at the Los Alamos National Laboratory (LANL) require that the Department of Energy protect the bald eagle (Haliaeetus leucocephalus), a state and federally listed species, from stressors such as contaminants. A preliminary risk assessment of the bald eagle was performed using a custom FORTRAN code, ECORSK5, and the geographical information system. Estimated exposure doses to the eagle for radionuclide, inorganic metal, and organic contaminants were derived for varying ratios of aquatic vs. terrestrial simulated diet and compared against toxicity reference values to generate hazard indices (His). HI results indicate that no appreciable impact to the bald eagle is expected from contaminants at LANL from soil ingestion and food consumption pathways. This includes a measure of cumulative effects from multiple contaminants that assumes linear additive toxicity. Improving model realism by weighting simulated eagle foraging based on distance from potential roost sites increased the HI by 76%, but still to inconsequential levels. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, eagle habitat, facility siting, and/or facility operations in order to maintain risk from contaminants at low levels.

  8. Can virtual reality exposure therapy gains be generalized to real-life? : A meta-analysis of studies applying behavioral assessments

    NARCIS (Netherlands)

    Morina, Nexhmedin; Ijntema, Hiske; Meyerbröker, Katharina; Emmelkamp, Paul M G

    2015-01-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials

  9. AN ASSESSMENT OF SPACEBORNE NEAR-NADIR INTERFEROMETRIC SAR PERFORMANCE OVER INLAND WATERS WITH REAL

    Directory of Open Access Journals (Sweden)

    H. Tan

    2018-04-01

    Full Text Available Elevation measurements of the continental water surface have been poorly collected with in situ measurements or occasionally with conventional altimeters with low accuracy. Techniques using InSAR at near-nadir angles to measure the inland water elevation with large swath and with high accuracy have been proposed, for instance, the WSOA on Jason 2 and the KaRIn on SWOT. However, the WSOA was abandoned unfortunately and the SWOT is planned to be launched in 2021. In this paper, we show real acquisitions of the first spaceborne InSAR of such kind, the Interferometric Imaging Radar Altimeter (InIRA, which has been working on Tiangong II spacecraft since 2016. We used the 90-m SRTM DEM as a reference to estimate the phase offset, and then an empirical calibration model was used to correct the baseline errors.

  10. An Assessment of Spaceborne Near-Nadir Interferometric SAR Performance Over Inland Waters with Real

    Science.gov (United States)

    Tan, H.; Li, S. Y.; Liu, Z. W.

    2018-04-01

    Elevation measurements of the continental water surface have been poorly collected with in situ measurements or occasionally with conventional altimeters with low accuracy. Techniques using InSAR at near-nadir angles to measure the inland water elevation with large swath and with high accuracy have been proposed, for instance, the WSOA on Jason 2 and the KaRIn on SWOT. However, the WSOA was abandoned unfortunately and the SWOT is planned to be launched in 2021. In this paper, we show real acquisitions of the first spaceborne InSAR of such kind, the Interferometric Imaging Radar Altimeter (InIRA), which has been working on Tiangong II spacecraft since 2016. We used the 90-m SRTM DEM as a reference to estimate the phase offset, and then an empirical calibration model was used to correct the baseline errors.

  11. Assessment of Cooperative and Heterogeneous Indoor Localization Algorithms with Real Radio Devices

    DEFF Research Database (Denmark)

    Nielsen, Jimmy Jessen; Noureddine, Hadi; Amiot, Nicolas

    2014-01-01

    In this paper we present results of real-life local- ization experiments performed in an unprecedented cooperative and heterogeneous wireless context. The experiments covered measurements of different radio devices packed together on a trolley, emulating a multi-standard Mobile Terminal (MT) along...... representative trajectories in a crowded office environment. Among all the radio access technologies involved in this campaign (including LTE, WiFi...), the focus is herein put mostly on Impulse Radio - Ultra Wideband (IR-UWB) and ZigBee sub-systems, which are enabled with peer-to-peer ranging capabilities based...... on Time of Arrival (ToA) estimation and Received Signal Strength (RSS) measurements respectively. Single-link model parameters are preliminarily drawn and discussed. In comparison with existing similar campaigns, new algorithms are also applied to the measurement data, showing the interest of advanced de...

  12. Assessment of bacterial pathogens in fresh rainwater and airborne particulate matter using Real-Time PCR

    Science.gov (United States)

    Kaushik, Rajni; Balasubramanian, Rajasekhar

    2012-01-01

    Bacterial pathogens in airborne particulate matter (PM) and in rainwater (RW) were detected using a robust and sensitive Real-Time PCR method. Both RW and PM were collected simultaneously in the tropical atmosphere of Singapore, which were then subjected to analysis for the presence of selected bacterial pathogens and potential pathogen of health concern ( Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa and Aeromonas hydrophila). These pathogens were found to be prevalent in both PM and RW samples with E. coli being the most prevalent potential pathogen in both types of samples. The temporal distribution of these pathogens in PM and RW was found to be similar to each other. Using the proposed microbiological technique, the atmospheric deposition (dry and wet deposition) of bacterial pathogens to lakes and reservoirs can be studied in view of growing concerns about the outbreak of waterborne diseases.

  13. Smartphone-Based Real-time Assessment of Swallowing Ability From the Swallowing Sound

    Science.gov (United States)

    Ueno, Tomoyuki; Teramoto, Yohei; Nakai, Kei; Hidaka, Kikue; Ayuzawa, Satoshi; Eguchi, Kiyoshi; Matsumura, Akira; Suzuki, Kenji

    2015-01-01

    Dysphagia can cause serious challenges to both physical and mental health. Aspiration due to dysphagia is a major health risk that could cause pneumonia and even death. The videofluoroscopic swallow study (VFSS), which is considered the gold standard for the diagnosis of dysphagia, is not widely available, expensive and causes exposure to radiation. The screening tests used for dysphagia need to be carried out by trained staff, and the evaluations are usually non-quantifiable. This paper investigates the development of the Swallowscope, a smartphone-based device and a feasible real-time swallowing sound-processing algorithm for the automatic screening, quantitative evaluation, and the visualisation of swallowing ability. The device can be used during activities of daily life with minimal intervention, making it potentially more capable of capturing aspirations and risky swallow patterns through the continuous monitoring. It also consists of a cloud-based system for the server-side analyzing and automatic sharing of the swallowing sound. The real-time algorithm we developed for the detection of dry and water swallows is based on a template matching approach. We analyzed the wavelet transformation-based spectral characteristics and the temporal characteristics of simultaneous synchronised VFSS and swallowing sound recordings of 25% barium mixed 3-ml water swallows of 70 subjects and the dry or saliva swallowing sound of 15 healthy subjects to establish the parameters of the template. With this algorithm, we achieved an overall detection accuracy of 79.3% (standard error: 4.2%) for the 92 water swallows; and a precision of 83.7% (range: 66.6%–100%) and a recall of 93.9% (range: 72.7%–100%) for the 71 episodes of dry swallows. PMID:27170905

  14. Smartphone-Based Real-time Assessment of Swallowing Ability From the Swallowing Sound.

    Science.gov (United States)

    Jayatilake, Dushyantha; Ueno, Tomoyuki; Teramoto, Yohei; Nakai, Kei; Hidaka, Kikue; Ayuzawa, Satoshi; Eguchi, Kiyoshi; Matsumura, Akira; Suzuki, Kenji

    2015-01-01

    Dysphagia can cause serious challenges to both physical and mental health. Aspiration due to dysphagia is a major health risk that could cause pneumonia and even death. The videofluoroscopic swallow study (VFSS), which is considered the gold standard for the diagnosis of dysphagia, is not widely available, expensive and causes exposure to radiation. The screening tests used for dysphagia need to be carried out by trained staff, and the evaluations are usually non-quantifiable. This paper investigates the development of the Swallowscope, a smartphone-based device and a feasible real-time swallowing sound-processing algorithm for the automatic screening, quantitative evaluation, and the visualisation of swallowing ability. The device can be used during activities of daily life with minimal intervention, making it potentially more capable of capturing aspirations and risky swallow patterns through the continuous monitoring. It also consists of a cloud-based system for the server-side analyzing and automatic sharing of the swallowing sound. The real-time algorithm we developed for the detection of dry and water swallows is based on a template matching approach. We analyzed the wavelet transformation-based spectral characteristics and the temporal characteristics of simultaneous synchronised VFSS and swallowing sound recordings of 25% barium mixed 3-ml water swallows of 70 subjects and the dry or saliva swallowing sound of 15 healthy subjects to establish the parameters of the template. With this algorithm, we achieved an overall detection accuracy of 79.3% (standard error: 4.2%) for the 92 water swallows; and a precision of 83.7% (range: 66.6%-100%) and a recall of 93.9% (range: 72.7%-100%) for the 71 episodes of dry swallows.

  15. Young adult non-smokers' exposure to real-world tobacco marketing: results of an ecological momentary assessment pilot study.

    Science.gov (United States)

    Rose, Shyanika W; Anesetti-Rothermel, Andrew; Elmasry, Hoda; Niaura, Ray

    2017-08-31

    The aims of this pilot study were to assess and characterize non-current smoking young adults' exposure to tobacco marketing through an ecological momentary assessment protocol. Ecological momentary assessment (EMA) consists of repeated measurement of momentary phenomena and is well-suited to capture sporadic experiences in the real-world, such as exposure to tobacco marketing. EMA has the potential to capture detailed information about real-world marketing exposures in ways that reduce recall bias and increase ecological validity. In this study, young adults (n = 31; ages 18-25) responded to random prompts regarding their momentary exposure to tobacco marketing via text messages on their smartphones for 14 days (n = 1798 observations). Unadjusted and adjusted analyses were conducted using multilevel logistic regression to assess the odds of exposure accounting for correlation of multiple repeated measures within individuals while controlling for variability between individuals. Respondents reported, on average, two momentary exposures to tobacco advertising in the 14-day study period. In adjusted analyses, African-American (aOR 3.36; 95% CI 1.07, 10.54) and Hispanic respondents (aOR 5.08; 95% CI 1.28, 20.13) were more likely to report exposure to tobacco advertising. Respondents were also more likely to report exposure when also exposed to others using tobacco products and when they were at stores compared with at home (aOR 14.82; 95% CI 3.61, 60.88). Non-smoking young adults report exposure to tobacco marketing particularly at the point-of-sale, with the highest likelihood of exposure among African-American and Hispanic young people. EMA protocols can be effective in assessing the potential impact of point-of-sale tobacco marketing on young adults.

  16. Does health intervention research have real world policy and practice impacts: testing a new impact assessment tool.

    Science.gov (United States)

    Cohen, Gillian; Schroeder, Jacqueline; Newson, Robyn; King, Lesley; Rychetnik, Lucie; Milat, Andrew J; Bauman, Adrian E; Redman, Sally; Chapman, Simon

    2015-01-01

    There is a growing emphasis on the importance of research having demonstrable public benefit. Measurements of the impacts of research are therefore needed. We applied a modified impact assessment process that builds on best practice to 5 years (2003-2007) of intervention research funded by Australia's National Health and Medical Research Council to determine if these studies had post-research real-world policy and practice impacts. We used a mixed method sequential methodology whereby chief investigators of eligible intervention studies who completed two surveys and an interview were included in our final sample (n = 50), on which we conducted post-research impact assessments. Data from the surveys and interviews were triangulated with additional information obtained from documentary analysis to develop comprehensive case studies. These case studies were then summarized and the reported impacts were scored by an expert panel using criteria for four impact dimensions: corroboration; attribution, reach, and importance. Nineteen (38%) of the cases in our final sample were found to have had policy and practice impacts, with an even distribution of high, medium, and low impact scores. While the tool facilitated a rigorous and explicit criterion-based assessment of post-research impacts, it was not always possible to obtain evidence using documentary analysis to corroborate the impacts reported in chief investigator interviews. While policy and practice is ideally informed by reviews of evidence, some intervention research can and does have real world impacts that can be attributed to single studies. We recommend impact assessments apply explicit criteria to consider the corroboration, attribution, reach, and importance of reported impacts on policy and practice. Impact assessments should also allow sufficient time between impact data collection and completion of the original research and include mechanisms to obtain end-user input to corroborate claims and reduce biases

  17. Assessment of real aging in selection process of replacement materials for stone monuments conservation.

    Directory of Open Access Journals (Sweden)

    Nicolas Concha Lozano

    2011-04-01

    Full Text Available En el ámbito de la sustitución de piedras en los monumentos, frecuentemente se plantea el problema de la selección de las piedras de reemplazo. De hecho, la reconstrucción debe ser estéticamente duradera, es decir, la piedra sustituida debe envejecer como la piedra original. Este estudio presenta una cadena de procesamiento de imágenes, desde la adquisición hasta la visualización, que permite comparar imágenes de piedras en varias etapas de su envejecimiento: recién extraída de la cantera, envejecida en edificios antiguos, y decapada con arena en monumentos recién restaurados. Esta herramienta incluye: (1 una calibración de cámara digital, (2 una transformación de adaptación cromática y (3 una etapa de redimensión. Para testear el método propuesto, un estudio de caso se llevó a cabo para evaluar la compatibilidad de tres tipos de caliza. Esta herramienta gráfica puede ayudar la selección de materiales de reemplazo con envejecimiento complejo como la piedra natural.

  18. Emergency Assessment of Debris-Flow Hazards from Basins Burned by the 2007 Buckweed Fire, Los Angeles County, Southern California

    Science.gov (United States)

    Cannon, Susan H.; Gartner, Joseph E.; Michael, John A.; Bauer, Mark A.; Stitt, Susan C.; Knifong, Donna L.; McNamara, Bernard J.; Roque, Yvonne M.

    2007-01-01

    INTRODUCTION The objective of this report is to present a preliminary emergency assessment of the potential for debris-flow generation from basins burned by the Buckweed Fire in Los Angeles County, southern California in 2007. Debris flows are among the most hazardous geologic phenomena; debris flows that followed wildfires in southern California in 2003 killed 16 people and caused tens of millions of dollars of property damage. A short period of even moderate rainfall on a burned watershed can lead to debris flows. Rainfall that is normally absorbed into hillslope soils can run off almost instantly after vegetation has been removed by wildfire. This causes much greater and more rapid runoff than is normal from creeks and drainage areas. Highly erodible soils in a burn scar allow flood waters to entrain large amounts of ash, mud, boulders, and unburned vegetation. Within the burned area and downstream, the force of rushing water, soil, and rock can destroy culverts, bridges, roadways, and buildings, potentially causing injury or death. This emergency debris-flow hazard assessment is presented as relative ranking of the predicted median volume of debris flows that can issue from basin outlets in response to 2.25 inches (57.15 mm) of rainfall over a 3-hour period. Such a storm has a 10-year return period. The calculation of debris flow volume is based on a multiple-regression statistical model that describes the median volume of material that can be expected from a recently burned basin as a function of the area burned at high and moderate severity, the basin area with slopes greater than or equal to 30 percent, and triggering storm rainfall. Cannon and others (2007) describe the methods used to generate the hazard maps. Identification of potential debris-flow hazards from burned drainage basins is necessary to issue warnings for specific basins, to make effective mitigation decisions, and to help plan evacuation timing and routes.

  19. Emergency Assessment of Debris-Flow Hazards from Basins Burned by the 2007 Canyon Fire, Los Angeles County, Southern California

    Science.gov (United States)

    Cannon, Susan H.; Gartner, Joseph E.; Michael, John A.; Bauer, Mark A.; Stitt, Susan C.; Knifong, Donna L.; McNamara, Bernard J.; Roque, Yvonne M.

    2007-01-01

    INTRODUCTION The objective of this report is to present a preliminary emergency assessment of the potential for debris-flow generation from basins burned by the Canyon Fire in Los Angeles County, southern California in 2007. Debris flows are among the most hazardous geologic phenomena; debris flows that followed wildfires in southern California in 2003 killed 16 people and caused tens of millions of dollars of property damage. A short period of even moderate rainfall on a burned watershed can lead to debris flows. Rainfall that is normally absorbed into hillslope soils can run off almost instantly after vegetation has been removed by wildfire. This causes much greater and more rapid runoff than is normal from creeks and drainage areas. Highly erodible soils in a burn scar allow flood waters to entrain large amounts of ash, mud, boulders, and unburned vegetation. Within the burned area and downstream, the force of rushing water, soil, and rock can destroy culverts, bridges, roadways, and buildings, potentially causing injury or death. This emergency debris-flow hazard assessment is presented as relative ranking of the predicted median volume of debris flows that can issue from basin outlets in response to 2.25 inches (57.15 mm) of rainfall over a 3-hour period. Such a storm has a 10-year return period. The calculation of debris flow volume is based on a multiple-regression statistical model that describes the median volume of material that can be expected from a recently burned basin as a function of the area burned at high and moderate severity, the basin area with slopes greater than or equal to 30 percent, and triggering storm rainfall. Cannon and others (2007) describe the methods used to generate the hazard maps. Identification of potential debris-flow hazards from burned drainage basins is necessary to issue warnings for specific basins, to make effective mitigation decisions, and to help plan evacuation timing and routes.

  20. Impact of Model Detail of Synchronous Machines on Real-time Transient Stability Assessment

    DEFF Research Database (Denmark)

    Weckesser, Johannes Tilman Gabriel; Jóhannsson, Hjörtur; Østergaard, Jacob

    2013-01-01

    In this paper, it is investigated how detailed the model of a synchronous machine needs to be in order to assess transient stability using a Single Machine Equivalent (SIME). The results will show how the stability mechanism and the stability assessment are affected by the model detail. In order...... of the machine models is varied. Analyses of the results suggest that a 4th-order model may be sufficient to represent synchronous machines in transient stability studies....

  1. Assessing and evaluating urban VOC emissions in mid-latitude megacities from intensive observations in Paris and Los Angeles

    Science.gov (United States)

    Borbon, A.; Gilman, J. B.; Kuster, W. C.; McKeen, S. A.; Holloway, J. S.; Gros, V.; Gaimoz, C.; Beekmann, M.; De Gouw, J. A.

    2011-12-01

    Volatile Organic Compounds (VOC) affect urban air quality and regional climate change by contributing to ozone formation and the build-up of Secondary Organic Aerosols (SOA). Quantification of VOC emissions is a first critical step to predict VOC environmental impacts and to design effective abatement strategies. Indeed, the quality of ozone and SOA forecasts strongly depends on an accurate knowledge of the primary VOC emissions. However, commonly used bottom-up approaches are highly uncertain due to source multiplicity (combustion processes, storage and distribution of fossil fuels, solvent use, etc.) because of numerous controlling factors (driving conditions, fuel type, temperature, radiation, etc.), and their great variability in time and space. Field observations of VOC and other trace gases can provide valuable top-down constraints to evaluate VOC emission inventories at urban scales. In addition, the implementation of emission reduction measures raises the question of the increasing importance of VOC sources other than traffic. Here, we will evaluate VOC emissions of two mid-latitude megacities in the Northern Hemisphere: the Greater Paris area (Europe) and Los Angeles (USA). In 2009 and 2010, three intensive field campaigns took place in Paris and Los Angeles in the framework of the MEGAPOLI (EU FP7) and CalNex-2010 projects, respectively. Very detailed measurements of aerosol composition and properties, and their gaseous VOC precursors were carried out at ground-based sites (urban center and suburban) and on various mobile platforms. This contribution uses a comprehensive suite of VOC measurements collected by GC-MS/FID techniques at ground-based sites in both cities by a source-receptor methodology. First, emission ratios were estimated from the observations (uncertainty of ± 20%) and compared regarding regional characteristics and European vs. Californian control policies. Then, determined emission ratios were used to assess the accuracy of up

  2. Assessment of surface solar irradiance derived from real-time modelling techniques and verification with ground-based measurements

    Science.gov (United States)

    Kosmopoulos, Panagiotis G.; Kazadzis, Stelios; Taylor, Michael; Raptis, Panagiotis I.; Keramitsoglou, Iphigenia; Kiranoudis, Chris; Bais, Alkiviadis F.

    2018-02-01

    This study focuses on the assessment of surface solar radiation (SSR) based on operational neural network (NN) and multi-regression function (MRF) modelling techniques that produce instantaneous (in less than 1 min) outputs. Using real-time cloud and aerosol optical properties inputs from the Spinning Enhanced Visible and Infrared Imager (SEVIRI) on board the Meteosat Second Generation (MSG) satellite and the Copernicus Atmosphere Monitoring Service (CAMS), respectively, these models are capable of calculating SSR in high resolution (1 nm, 0.05°, 15 min) that can be used for spectrally integrated irradiance maps, databases and various applications related to energy exploitation. The real-time models are validated against ground-based measurements of the Baseline Surface Radiation Network (BSRN) in a temporal range varying from 15 min to monthly means, while a sensitivity analysis of the cloud and aerosol effects on SSR is performed to ensure reliability under different sky and climatological conditions. The simulated outputs, compared to their common training dataset created by the radiative transfer model (RTM) libRadtran, showed median error values in the range -15 to 15 % for the NN that produces spectral irradiances (NNS), 5-6 % underestimation for the integrated NN and close to zero errors for the MRF technique. The verification against BSRN revealed that the real-time calculation uncertainty ranges from -100 to 40 and -20 to 20 W m-2, for the 15 min and monthly mean global horizontal irradiance (GHI) averages, respectively, while the accuracy of the input parameters, in terms of aerosol and cloud optical thickness (AOD and COT), and their impact on GHI, was of the order of 10 % as compared to the ground-based measurements. The proposed system aims to be utilized through studies and real-time applications which are related to solar energy production planning and use.

  3. Low-level waste drum staging building at Weapons Engineering Tritium Facility, TA-16, Los Alamos National Laboratory, Los Alamos, New Mexico. Environmental Assessment

    International Nuclear Information System (INIS)

    1994-08-01

    The proposed action is to place a 3 meter (m) by 4.5 m (10 ft x 15 ft) prefabricated storage building (transportainer) adjacent to the existing Weapons Engineering Tritium Facility (WETF) at Technical Area (TA-) 16, Los Alamos National Laboratory (LANL), and to use the building as a staging site for sealed 55 galllon drums of noncompactible waste contaminated with low levels of tritium (LLW). Up to eight drums of waste would be accumulated before the waste is moved by LANL Waste Management personnel to the existing on-site LLW disposal area at TA-54. The drum staging building would be placed on a bermed asphalt pad, near other existing accumulation structures for office trash and compactible LLW. The no-action alternative is to continue storing drums of LLW in the WETF laboratories where they occupy valuable work space, hamper movement of personnel and equipment, and require waste management personnel to enter those laboratories in order to remove filled drums. No new waste would be generated by implementing the proposed action; no changes or increases in WETF operations or waste production rate are anticipated as a result of staging drums of LLW outside the main laboratory building. The site for the LLW drum staging building would not impact any sensitive areas. Tritium emissions from the drums of LLW were included within the source term for normal operations at the WETF; the cumulative impacts would not be increased

  4. La diplomacia castellana durante el reinado de Juan II: la participación de los letrados de la cancillería real en las embajadas regias

    Directory of Open Access Journals (Sweden)

    Cañas Gálvez, Francisco de Paula

    2010-12-01

    Full Text Available A good part of the Castilian diplomatic corps of the first half of the 15th. century was coming from the bureaucratic - administrative structures of the Royal Chancery. The present work try to approach the study of those embassies and diplomatic missions and the participation of these officials doing a special support in his professional and court profile.

    Una buena parte del cuerpo diplomático castellano de la primera mitad del siglo XV procedía de las estructuras burocrático-administrativas de la Cancillería Real. El presente trabajo pretender abordar el estudio de aquellas embajadas y misiones diplomáticas y la participación de estos oficiales haciendo un especial hincapié en su perfil profesional y cortesano.

  5. Real-Time Dynamic Brake Assessment Proof of Concept Final Report

    Energy Technology Data Exchange (ETDEWEB)

    Lascurain, Mary Beth [ORNL; Franzese, Oscar [ORNL; Capps, Gary J [ORNL

    2011-11-01

    This proof-of-concept research was performed to explore the feasibility of using real-world braking data from commercial motor vehicles to make a diagnosis of brake condition similar to that of the performance-based brake tester (PBBT). This was done by determining the relationship between pressure and brake force (P-BF), compensating for the gross vehicle weight (GVW). The nature of this P-BF relationship (e.g., low braking force for a given brake application pressure) may indicate brake system problems. In order to determine the relationship between brake force and brake application pressure, a few key parameters of duty cycle information were collected. Because braking events are often brief, spanning only a few seconds, a sample rate of 10 Hz was needed. The algorithm under development required brake application pressure and speed (from which deceleration was calculated). Accurate weight estimation was also needed to properly derive the braking force from the deceleration. In order to ensure that braking force was the predominant factor in deceleration for the segments of data used in analysis, the data was screened for grade as well. Also, the analysis needed to be based on pressures above the crack pressure. The crack pressure is the pressure below which the individual brakes are not applied due the nature of the mechanical system. This value, which may vary somewhat from one wheel end to another, is approximately 10 psi. Therefore, only pressures 15 psi and above were used in the analysis. The Department of Energy s Medium Truck Duty Cycle research has indicated that under the real-world circumstances of the test vehicle brake pressures of up to approximately 30 psi can be expected. Several different types of data were collected during the testing task of this project. Constant-pressure stopping tests were conducted at several combinations of brake application pressure (15, 20, 25, and 30 psi), load conditions (moderately and fully laden), and speeds (20 and

  6. La base electoral de Obama, redes sociales virtuales y reales: los casos de generation engage y moms for Obama The electoral support of Obama, real and social virtual networks: the case of ‘Generation Engage’ and ‘Moms for Obama’

    Directory of Open Access Journals (Sweden)

    José Luis González

    Full Text Available ResumenDespués de un año de la victoria electoral de Barack Obama, el actual presidente de los Estados Unidos mantiene unas cotas de popularidad muy elevadas, máxime si tenemos en cuenta la actual coyuntura de crisis que afecta de manera frontal a los Estados Unidos. El presente artículo, a partir del estudio de un estado concreto: Carolina del Norte, explica cuáles son las bases sobre las que se sustenta dicho apoyo, bases que tienen que ver con un trabajo realizado desde las elecciones primarias del Partido Demócrata y que se sustentan en un adecuado uso de las redes sociales, tanto virtuales como reales. Para demostrar esta hipótesis, se muestran los resultados de un vasto trabajo de campo realizado, fundamentalmente con dos redes que han centrado sus esfuerzos en afianzar el voto joven y el voto femenino: ‘Generation Engage’ y ‘Mom for Obama’.AbstractAfter one year of the election victory of Barack Obama, the current president of the United Status, has a very high level of popularity, especially bearing in mind the current crisis that affects the United States. This article, from the study of a particular state: North Carolina, explains the keys of support, keys that are related to work done since the primaries and the Democratic Party behind in an appropriate use of social networks, both virtual and real. To prove this hypothesis, we show the results of an extensive field work carried out mainly with two networks that have focused their efforts on strengthening the youth vote and women voters: Generation Engage and 'Moms for Obama.

  7. Real enough: using virtual public speaking environments to evoke feelings and behaviors targeted in stuttering assessment and treatment.

    Science.gov (United States)

    Brundage, Shelley B; Hancock, Adrienne B

    2015-05-01

    Virtual reality environments (VREs) are computer-generated, 3-dimensional worlds that allow users to experience situations similar to those encountered in the real world. The purpose of this study was to investigate VREs for potential use in assessing and treating persons who stutter (PWS) by determining the extent to which PWS's affective, behavioral, and cognitive measures in a VRE correlate with those same measures in a similar live environment. Ten PWS delivered speeches-first to a live audience and, on another day, to 2 virtual audiences (neutral and challenging audiences). Participants completed standard tests of communication apprehension and confidence prior to each condition, and frequency of stuttering was measured during each speech. Correlational analyses revealed significant, positive correlations between virtual and live conditions for affective and cognitive measures as well as for frequency of stuttering. These findings suggest that virtual public speaking environments engender affective, behavioral, and cognitive reactions in PWS that correspond to those experienced in the real world. Therefore, the authentic, safe, and controlled environments provided by VREs may be useful for stuttering assessment and treatment.

  8. Bayesian Algorithm Implementation in a Real Time Exposure Assessment Model on Benzene with Calculation of Associated Cancer Risks

    Directory of Open Access Journals (Sweden)

    Pavlos A. Kassomenos

    2009-02-01

    Full Text Available The objective of the current study was the development of a reliable modeling platform to calculate in real time the personal exposure and the associated health risk for filling station employees evaluating current environmental parameters (traffic, meteorological and amount of fuel traded determined by the appropriate sensor network. A set of Artificial Neural Networks (ANNs was developed to predict benzene exposure pattern for the filling station employees. Furthermore, a Physiology Based Pharmaco-Kinetic (PBPK risk assessment model was developed in order to calculate the lifetime probability distribution of leukemia to the employees, fed by data obtained by the ANN model. Bayesian algorithm was involved in crucial points of both model sub compartments. The application was evaluated in two filling stations (one urban and one rural. Among several algorithms available for the development of the ANN exposure model, Bayesian regularization provided the best results and seemed to be a promising technique for prediction of the exposure pattern of that occupational population group. On assessing the estimated leukemia risk under the scope of providing a distribution curve based on the exposure levels and the different susceptibility of the population, the Bayesian algorithm was a prerequisite of the Monte Carlo approach, which is integrated in the PBPK-based risk model. In conclusion, the modeling system described herein is capable of exploiting the information collected by the environmental sensors in order to estimate in real time the personal exposure and the resulting health risk for employees of gasoline filling stations.

  9. Bayesian algorithm implementation in a real time exposure assessment model on benzene with calculation of associated cancer risks.

    Science.gov (United States)

    Sarigiannis, Dimosthenis A; Karakitsios, Spyros P; Gotti, Alberto; Papaloukas, Costas L; Kassomenos, Pavlos A; Pilidis, Georgios A

    2009-01-01

    The objective of the current study was the development of a reliable modeling platform to calculate in real time the personal exposure and the associated health risk for filling station employees evaluating current environmental parameters (traffic, meteorological and amount of fuel traded) determined by the appropriate sensor network. A set of Artificial Neural Networks (ANNs) was developed to predict benzene exposure pattern for the filling station employees. Furthermore, a Physiology Based Pharmaco-Kinetic (PBPK) risk assessment model was developed in order to calculate the lifetime probability distribution of leukemia to the employees, fed by data obtained by the ANN model. Bayesian algorithm was involved in crucial points of both model sub compartments. The application was evaluated in two filling stations (one urban and one rural). Among several algorithms available for the development of the ANN exposure model, Bayesian regularization provided the best results and seemed to be a promising technique for prediction of the exposure pattern of that occupational population group. On assessing the estimated leukemia risk under the scope of providing a distribution curve based on the exposure levels and the different susceptibility of the population, the Bayesian algorithm was a prerequisite of the Monte Carlo approach, which is integrated in the PBPK-based risk model. In conclusion, the modeling system described herein is capable of exploiting the information collected by the environmental sensors in order to estimate in real time the personal exposure and the resulting health risk for employees of gasoline filling stations.

  10. The effectiveness of the Geritalk communication skills course: a real-time assessment of skill acquisition and deliberate practice.

    Science.gov (United States)

    Gelfman, Laura P; Lindenberger, Elizabeth; Fernandez, Helen; Goldberg, Gabrielle R; Lim, Betty B; Litrivis, Evgenia; O'Neill, Lynn; Smith, Cardinale B; Kelley, Amy S

    2014-10-01

    Communication skills are critical in Geriatrics and Palliative Medicine because these patients confront complex clinical scenarios. We evaluated the effectiveness of the Geritalk communication skills course by comparing pre- and post-course real-time assessment of the participants leading family meetings. We also evaluated the participants' sustained skills practice. We compare the participants' skill acquisition before and after Geritalk using a direct observation Family Meeting Communication Assessment Tool and assess their deliberate practice at follow-up. First-year Geriatrics or Palliative Medicine fellows at Mount Sinai Medical Center and the James J. Peters Bronx VA Medical Center participated in Geritalk. Pre- and post-course family meeting assessments were compared. An average net gain of 6.8 skills represented a greater than 20% improvement in use of applicable skills. At two month follow-up, most participants reported deliberate practice of fundamental and advanced skills. This intensive training and family meeting assessment offers evidence-based communication skills training. Published by Elsevier Inc.

  11. Water resources planning under climate change: Assessing the robustness of real options for the Blue Nile

    Science.gov (United States)

    Jeuland, Marc; Whittington, Dale

    2014-03-01

    This article presents a methodology for planning new water resources infrastructure investments and operating strategies in a world of climate change uncertainty. It combines a real options (e.g., options to defer, expand, contract, abandon, switch use, or otherwise alter a capital investment) approach with principles drawn from robust decision-making (RDM). RDM comprises a class of methods that are used to identify investment strategies that perform relatively well, compared to the alternatives, across a wide range of plausible future scenarios. Our proposed framework relies on a simulation model that includes linkages between climate change and system hydrology, combined with sensitivity analyses that explore how economic outcomes of investments in new dams vary with forecasts of changing runoff and other uncertainties. To demonstrate the framework, we consider the case of new multipurpose dams along the Blue Nile in Ethiopia. We model flexibility in design and operating decisions—the selection, sizing, and sequencing of new dams, and reservoir operating rules. Results show that there is no single investment plan that performs best across a range of plausible future runoff conditions. The decision-analytic framework is then used to identify dam configurations that are both robust to poor outcomes and sufficiently flexible to capture high upside benefits if favorable future climate and hydrological conditions should arise. The approach could be extended to explore design and operating features of development and adaptation projects other than dams.

  12. Assessment of disintegrant efficacy with fractal dimensions from real-time MRI.

    Science.gov (United States)

    Quodbach, Julian; Moussavi, Amir; Tammer, Roland; Frahm, Jens; Kleinebudde, Peter

    2014-11-20

    An efficient disintegrant is capable of breaking up a tablet in the smallest possible particles in the shortest time. Until now, comparative data on the efficacy of different disintegrants is based on dissolution studies or the disintegration time. Extending these approaches, this study introduces a method, which defines the evolution of fractal dimensions of tablets as surrogate parameter for the available surface area. Fractal dimensions are a measure for the tortuosity of a line, in this case the upper surface of a disintegrating tablet. High-resolution real-time MRI was used to record videos of disintegrating tablets. The acquired video images were processed to depict the upper surface of the tablets and a box-counting algorithm was used to estimate the fractal dimensions. The influence of six different disintegrants, of different relative tablet density, and increasing disintegrant concentration was investigated to evaluate the performance of the novel method. Changing relative densities hardly affect the progression of fractal dimensions, whereas an increase in disintegrant concentration causes increasing fractal dimensions during disintegration, which are also reached quicker. Different disintegrants display only minor differences in the maximal fractal dimension, yet the kinetic in which the maximum is reached allows a differentiation and classification of disintegrants. Copyright © 2014 Elsevier B.V. All rights reserved.

  13. Engaging and Assessing Students through their Electronic Devices and Real Time Quizzes

    Directory of Open Access Journals (Sweden)

    E. Ferrándiz

    2016-10-01

    Full Text Available This paper describes a teaching experience using Socrative, a third party electronic tool, for real-time questioning in lectures of Econometrics.  Econometrics is a theoretical-practical subject, but traditionally a large proportion of our students tend to focus on the practical and discard the theory, often skipping classes on theory and avoiding studying its content, probably motivated by its complexity. As a consequence, students’ marks obtained in the theoretical part of the exam are usually low. In this context, we put forward a change in our teaching methodology to include the use of Socrative, a freely available app, that allows students to answer teachers’ short, true/false, or multiple choice questions posed during each class using their smartphones (or other electronic devices with Internet connection. The objectives of this project are twofold: 1 to engage students and increase attendance at lectures; 2 to improve feedback on the learning process. The results of a survey of a sample of 186 students reveal that Socrative has been an effective tool for achieving these objectives.

  14. Foundation stones for a real socio-environmental integration in projects' impact assessments

    Science.gov (United States)

    Andres Dominguez-Gomez, J.

    2015-04-01

    In the last twenty years, both the increase in academic production and the expansion of professional involvement in Environmental Impact Assessment (EIA) and Social Impact Assessment (SIA), have evidenced growing scientific and business interest in risk and impact analysis. However, this growth has not brought with it a parallel progress in addressing their main shortcomings: insufficient integration of environmental and social features into development project analyses and, in cases where the social aspects are considered, technical-methodological failings in their diagnosis and assessment. It is clear that these weaknesses carry with them substantial threats to the sustainability (social, environmental and economic) of schemes which impact on the environment, and in consequence, to the local contexts where they are carried out and to the delicate balance of the global ecosystem. This paper argue that, in a sociological context of growing complexity, four foundation-stones are required to underpin research methodologies (for both diagnosis and assessment) in the socio-environmental risks of development projects: a theoretical foundation in actor-network theory; an ethical grounding in values which are internationally recognized though not always carried through into practice; a (new) epistemological-scientific base; and a methodological foundation in social participation.

  15. Wide-Area Assessment of Aperiodic Small Signal Rotor Angle Stability in Real-Time

    DEFF Research Database (Denmark)

    Jóhannsson, Hjörtur; Nielsen, Arne Hejde; Østergaard, Jacob

    2014-01-01

    in rotor angle and a loss of synchronism, referred to as aperiodic small signal instability. The paper provides the theoretical background of the method and an analytical assessment criterion. Furthermore, a mathematical mapping of the generators' operating points that enables informative visualization...

  16. Real-Time Live Confocal Fluorescence Microscopy as a New Tool for Assessing Platelet Vitality.

    Science.gov (United States)

    Hermann, Martin; Nussbaumer, Oliver; Knöfler, Ralf; Hengster, Paul; Nussbaumer, Walter; Streif, Werner

    2010-01-01

    BACKGROUND: Assessment of platelet vitality is important for patients presenting with inherited or acquired disorders of platelet function and for quality assessment of platelet concentrates. METHODS: Herein we combined live stains with intra-vital confocal fluorescence microscopy in order to obtain an imaging method that allows fast and accurate assessment of platelet vitality. Three fluorescent dyes, FITC-coupled wheat germ agglutinin (WGA), tetramethylrhodamine methyl ester perchlorate (TMRM) and acetoxymethylester (Rhod-2), were used to assess platelet morphology, mitochondrial activity and intra-platelet calcium levels. Microscopy was performed with a microlens-enhanced Nipkow spinning disk-based system allowing live confocal imaging. RESULTS: Comparison of ten samples of donor platelets collected before apheresis and platelets collected on days 5 and 7 of storage showed an increase in the percentage of Rhod-2-positive platelets from 3.6 to 47 and finally to 71%. Mitochondrial potential was demonstrated in 95.4% of donor platelets and in 92.5% of platelets stored for 7 days. CONCLUSION: Such fast and accurate visualization of known key parameters of platelet function could be of relevance for studies addressing the quality of platelets after storage and additional manipulation, such as pathogen inactivation, as well as for the analysis of inherited platelet function disorders.

  17. Integration and Assessment of Multiple Mobile Manipulators in a Real-World Industrial Production Facility

    DEFF Research Database (Denmark)

    Bøgh, Simon; Schou, Casper; Rühr, Thomas

    2014-01-01

    This paper presents a large-scale research experiment carried out within the TAPAS project, where multiple mobile manipulators were integrated and assessed in an industrial context. We consider an industrial scenario in which mobile manipulators naturally extend automation of logistic tasks towar...

  18. The Assessment of the Intelligence of Latinos in the United States. (La Medicion de la Inteligencia de los Latinos en los Estados Unidos).

    Science.gov (United States)

    Cauce, Ana M.; And Others

    Most of the research on the assessment of the intelligence of Latinos in the United States appears to be based on some possibly erroneous or at least dubious assumptions. Among these are the following: (1) the assumption of bilinguality; (2) the assumption of equal proficiency in the English language; (3) the assumption of the equivalence of…

  19. Teacher Directed Design: Content Knowledge, Pedagogy and Assessment under the Nevada K-12 Real-Time Seismic Network

    Science.gov (United States)

    Cantrell, P.; Ewing-Taylor, J.; Crippen, K. J.; Smith, K. D.; Snelson, C. M.

    2004-12-01

    Education professionals and seismologists under the emerging SUN (Shaking Up Nevada) program are leveraging the existing infrastructure of the real-time Nevada K-12 Seismic Network to provide a unique inquiry based science experience for teachers. The concept and effort are driven by teacher needs and emphasize rigorous content knowledge acquisition coupled with the translation of that knowledge into an integrated seismology based earth sciences curriculum development process. We are developing a pedagogical framework, graduate level coursework, and materials to initiate the SUN model for teacher professional development in an effort to integrate the research benefits of real-time seismic data with science education needs in Nevada. A component of SUN is to evaluate teacher acquisition of qualified seismological and earth science information and pedagogy both in workshops and in the classroom and to assess the impact on student achievement. SUN's mission is to positively impact earth science education practices. With the upcoming EarthScope initiative, the program is timely and will incorporate EarthScope real-time seismic data (USArray) and educational materials in graduate course materials and teacher development programs. A number of schools in Nevada are contributing real-time data from both inexpensive and high-quality seismographs that are integrated with Nevada regional seismic network operations as well as the IRIS DMC. A powerful and unique component of the Nevada technology model is that schools can receive "stable" continuous live data feeds from 100's seismograph stations in Nevada, California and world (including live data from Earthworm systems and the IRIS DMC BUD - Buffer of Uniform Data). Students and teachers see their own networked seismograph station within a global context, as participants in regional and global monitoring. The robust real-time Internet communications protocols invoked in the Nevada network provide for local data acquisition

  20. Optimal estimate of the coolant flow in the assemblies of a BWR of natural circulation in real time; Estimacion optima del flujo de refrigerante en los ensambles de un BWR de circulacion natural en tiempo real

    Energy Technology Data Exchange (ETDEWEB)

    Valle H, J.; Morales S, J. B. [UNAM, Facultad de Ingenieria, Division de Estudios de Posgrado, Laboratorio de Analisis de Ingenieria de Reactores Nucleares, Paseo Cuauhnahuac 8532, Col. Progreso, 62550 Jiutepec, Morelos (Mexico); Espinosa P, G., E-mail: julfi_jg@yahoo.com.mx [Universidad Autonoma Metropolitana, Unidad Iztapalapa, Av. San Rafael Atlixco 186, Col. Vicentina, 09340 Mexico D. F. (Mexico)

    2012-10-15

    The present work exposes the design and the implementation of an advanced controller that allows estimating the coolant flow in the fuel assemblies of a BWR reactor of natural circulation in real time. To be able to reduce the penalizations that are established in the calculations of the operation limits due to the magnitude of the uncertainties in the coolant flows of a natural circulation reactor, is the objective of this research. In this work the construction of the optimal controller that allows estimating the coolant flows in a fuel channels group of the reactor is shown, as well as the operation of this applied to a reduced order model that simulates the dynamics of a natural circulation reactor. The controller design required of an estimator of the valuation variables not directly of the plant and of the estimates use of the local distributions of the coolant flow. The controller construction of the estimator was based mathematically in the filter Kalman whose algorithm allows to be carried out an advanced control of the system. To prove the estimator operation was development a simplified model that reproduces the basic dynamics of the flowing coolant in the reactor, which works as observer of the system, this model is coupled by means of the estimator controller to a detail model of the plant. The results are presented by means of graphics of the interest variables and the estimate flow, and they are documented in the chart that is presented at the end of this article. (Author)

  1. An Entropy Approach to Disclosure Risk Assessment: Lessons from Real Applications and Simulated Domains

    Science.gov (United States)

    Airoldi, Edoardo M.; Bai, Xue; Malin, Bradley A.

    2011-01-01

    We live in an increasingly mobile world, which leads to the duplication of information across domains. Though organizations attempt to obscure the identities of their constituents when sharing information for worthwhile purposes, such as basic research, the uncoordinated nature of such environment can lead to privacy vulnerabilities. For instance, disparate healthcare providers can collect information on the same patient. Federal policy requires that such providers share “de-identified” sensitive data, such as biomedical (e.g., clinical and genomic) records. But at the same time, such providers can share identified information, devoid of sensitive biomedical data, for administrative functions. On a provider-by-provider basis, the biomedical and identified records appear unrelated, however, links can be established when multiple providers’ databases are studied jointly. The problem, known as trail disclosure, is a generalized phenomenon and occurs because an individual’s location access pattern can be matched across the shared databases. Due to technical and legal constraints, it is often difficult to coordinate between providers and thus it is critical to assess the disclosure risk in distributed environments, so that we can develop techniques to mitigate such risks. Research on privacy protection has so far focused on developing technologies to suppress or encrypt identifiers associated with sensitive information. There is growing body of work on the formal assessment of the disclosure risk of database entries in publicly shared databases, but a less attention has been paid to the distributed setting. In this research, we review the trail disclosure problem in several domains with known vulnerabilities and show that disclosure risk is influenced by the distribution of how people visit service providers. Based on empirical evidence, we propose an entropy metric for assessing such risk in shared databases prior to their release. This metric assesses risk by

  2. Seismic Monitoring To Assess Performance Of Structures In Near-Real Time: Recent Progress

    International Nuclear Information System (INIS)

    Celebi, Mehmet

    2008-01-01

    Earlier papers have described how observed data from classical accelerometers deployed in structures or from differential GPS with high sampling ratios deployed at roofs of tall buildings can be configured to establish seismic health monitoring of structures. In these configurations, drift ratios 1 are the main parametric indicator of damage condition of a structure or component of a structure.Real-time measurement of displacements are acquired either by double integration of accelerometer time-series data, or by directly using GPS. Recorded sensor data is then related to the performance level of a building. Performance-based design method stipulates that for a building the amplitude of relative displacement of the roof of a building (with respect to its base) indicates its performance.Usually, drift ratio is computed using relative displacement between two consecutive floors. When accelerometers are used, a specific software is used to compute displacements and drift ratios in realtime by double integration of accelerometer data from several floors. However, GPS-measured relative displacements are limited to being acquired only at the roof with respect to its reference base. Thus, computed drift ratio is the average drift ratio for the whole building. Until recently, the validity of measurements using GPS was limited to long-period structures (T>1 s) because GPS systems readily available were limited to 10-20 samples per seconds (sps) capability. However, presently, up to 50 sps differential GPS systems are available on the market and have been successfully used to monitor drift ratios [1,2]--thus enabling future usefulness of GPS to all types of structures. Several levels of threshold drift ratios can be postulated in order to make decisions for inspections and/or occupancy.Experience with data acquired from both accelerometers and GPS deployments indicates that they are reliable and provide pragmatic alternatives to alert the owners and other authorized parties

  3. A spatially-dynamic preliminary risk assessment of the American peregrine falcon at the Los Alamos National Laboratory (version 1)

    International Nuclear Information System (INIS)

    Gallegos, A.F.; Gonzales, G.J.; Bennett, K.D.

    1997-06-01

    The Endangered Species Act and the Record of Decision on the Dual Axis Radiographic Hydrodynamic Test Facility at the Los Alamos National Laboratory require protection of the American peregrine falcon. A preliminary risk assessment of the peregrine was performed using a custom FORTRAN model and a geographical information system. Estimated doses to the falcon were compared against toxicity reference values to generate hazard indices. Hazard index results indicated no unacceptable risk to the falcon from the soil ingestion pathway, including a measure of cumulative effects from multiple contaminants that assumes a linear additive toxicity type. Scaling home ranges on the basis of maximizing falcon height for viewing prey decreased estimated risk by 69% in a canyons-based home range and increased estimated risk by 40% in a river-based home range. Improving model realism by weighting simulated falcon foraging based on distance from potential nest sites decreased risk by 93% in one exposure unit and by 82% in a second exposure unit. It was demonstrated that choice of toxicity reference values can have a substantial impact on risk estimates. Adding bioaccumulation factors for several organics increased partial hazard quotients by a factor of 110, but increased the mean hazard index by only 0.02 units. Adding a food consumption exposure pathway in the form of biomagnification factors for 15 contaminants of potential ecological concern increased the mean hazard index to 1.16 (± 1.0), which is above the level of acceptability (1.0). Aroclor-1254, dichlorodiphenyltrichlorethane (DDT) and dichlorodiphenylethelyne (DDE) accounted for 81% of the estimated risk that includes soil ingestion and food consumption Contaminant pathways and a biomagnification component. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, falcon habitat, facility siting, and/or facility operations. 123 refs., 10 figs., 2 tabs

  4. A spatially-dynamic preliminary risk assessment of the American peregrine falcon at the Los Alamos National Laboratory (version 1)

    Energy Technology Data Exchange (ETDEWEB)

    Gallegos, A.F.; Gonzales, G.J.; Bennett, K.D. [and others

    1997-06-01

    The Endangered Species Act and the Record of Decision on the Dual Axis Radiographic Hydrodynamic Test Facility at the Los Alamos National Laboratory require protection of the American peregrine falcon. A preliminary risk assessment of the peregrine was performed using a custom FORTRAN model and a geographical information system. Estimated doses to the falcon were compared against toxicity reference values to generate hazard indices. Hazard index results indicated no unacceptable risk to the falcon from the soil ingestion pathway, including a measure of cumulative effects from multiple contaminants that assumes a linear additive toxicity type. Scaling home ranges on the basis of maximizing falcon height for viewing prey decreased estimated risk by 69% in a canyons-based home range and increased estimated risk by 40% in a river-based home range. Improving model realism by weighting simulated falcon foraging based on distance from potential nest sites decreased risk by 93% in one exposure unit and by 82% in a second exposure unit. It was demonstrated that choice of toxicity reference values can have a substantial impact on risk estimates. Adding bioaccumulation factors for several organics increased partial hazard quotients by a factor of 110, but increased the mean hazard index by only 0.02 units. Adding a food consumption exposure pathway in the form of biomagnification factors for 15 contaminants of potential ecological concern increased the mean hazard index to 1.16 ({+-} 1.0), which is above the level of acceptability (1.0). Aroclor-1254, dichlorodiphenyltrichlorethane (DDT) and dichlorodiphenylethelyne (DDE) accounted for 81% of the estimated risk that includes soil ingestion and food consumption Contaminant pathways and a biomagnification component. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, falcon habitat, facility siting, and/or facility operations. 123 refs., 10 figs., 2 tabs.

  5. Transweb - real time transportation threat assessment analysis tool: look what the future may bring for energy related infrastructure?

    International Nuclear Information System (INIS)

    Dilger, F.; Ballard, J.D.

    2005-01-01

    Full text: Transweb is envisioned as a transportation threat assessment program and this real time GIS based web assessment too (a.k.a., GTA for GIS threat assessment) can be used to plan railroad or highway shipments of hazardous waste (e.g., toxic industrial chemicals - TIC's) and high-level nuclear waste materials (e.g., like those destined for Yucca Mountain - HLW) that may be used in energy production facilities. Transweb will become a vulnerability mapping and analysis tool that can be used by transportation planners, emergency response personnel, security/safety managers, and law enforcement to route such shipments, make contingency plans in the event of altered road or rail conditions, and/or to assist in the response to an accident or human initiated event like terrorism. The initial phase of the project will seek to establish the protocol on highway shipments and follow up phases will focus on rail GTA's. This paper will report on the initial development of this analytical technique, define the problems associated with such analysis, and offer examples of its analytical possibilities for threat assessment relative to energy related facilities like nuclear power generation stations. (author)

  6. Floodplain and Wetland Assessment for the Mortandad Wetland Enhancement and the DP Dissipater Projects at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Hathcock, Charles Dean [Los Alamos National Laboratory

    2017-03-31

    This floodplain and wetland assessment was prepared in accordance with 10 Code of Federal Regulations (CFR) 1022 Compliance with Floodplain and Wetland Environmental Review Requirements, which was promulgated to implement the U.S. Department of Energy (DOE) requirements under Executive Order 11988 Floodplain Management and Executive Order 11990 Wetlands Protection. According to 10 CFR 1022, a 100-year floodplain is defined as “the lowlands adjoining inland and coastal waters and relatively flat areas and flood prone areas of offshore islands” and a wetland is defined as “an area that is inundated or saturated by surface or groundwater at a frequency and duration sufficient to support, and that under normal circumstances does support, a prevalence of vegetation typically adapted for life in saturated soil conditions, including swamps, marshes, bogs, and similar areas.” In this action, DOE is proposing two projects to improve wetland and floodplain function at Los Alamos National Laboratory (LANL). The proposed work will comply with corrective action requirements under the Settlement Agreement and Stipulated Final Compliance Order (Settlement Agreement)1 Number HWB-14-20. The first project is located in Technical Areas (TA)-03 in upper Mortandad Canyon. The upper Mortandad wetlands have existing stormwater controls that need to be rehabilitated. Head-cut formation is occurring at the downstream portion of the wetland. This project will repair damages to the wetland and reduce the future erosion potential. The second project is located in TA-21 in Delta Prime (DP) Canyon. The intent of the DP Dissipater Project in DP Canyon is to install stormwater control structures in DP Canyon to retain low channel flows and reduce downstream sediment transport as well as peak flows during low and moderate storm events. Due to increased erosion, the stream bank in this area has unstable vertical walls within the stream channel. The DOE prepared this floodplain and wetland

  7. Assessing the Possibility of Implementing Tools of Technical Analysys for Real Estate Market Analysis

    Directory of Open Access Journals (Sweden)

    Brzezicka Justyna

    2016-06-01

    Full Text Available Technical analysis (TA and its different aspects are widely used to study the capital market. In the traditional approach, this analysis is used to determine the probability of changes in current rates on the basis of their past changes, accounting for factors which had, have or may have an influence on shaping the supply and demand of a given asset. In the practical sense, TA is a set of techniques used for assessing the value of an asset based on the analysis of the asset's trajectories as well as statistical tools.

  8. Real-time SWMF-Geospace at CCMC: assessing the quality of output from continuous operational simulations

    Science.gov (United States)

    Liemohn, M. W.; Welling, D. T.; De Zeeuw, D.; Kuznetsova, M. M.; Rastaetter, L.; Ganushkina, N. Y.; Ilie, R.; Toth, G.; Gombosi, T. I.; van der Holst, B.

    2016-12-01

    The ground-based magnetometer index Dst is a decent measure of the near-Earth current systems, in particular those in the storm-time inner magnetosphere. The ability of a large-scale, physics-based model to reproduce, or even predict, this index is therefore a tangible measure of the overall validity of the code for space weather research and space weather operational usage. Experimental real-time simulations of the Space Weather Modeling Framework (SWMF) are conducted at the Community Coordinated Modeling Center (CCMC), with results available there (http://ccmc.gsfc.nasa.gov/realtime.php), through the CCMC Integrated Space Weather Analysis (iSWA) site (http://iswa.ccmc.gsfc.nasa.gov/IswaSystemWebApp/), and the Michigan SWMF site (http://csem.engin.umich.edu/realtime). Presently, two configurations of the SWMF are running in real time at CCMC, both focusing on the geospace modules, using the BATS-R-US magnetohydrodynamic model, the Ridley Ionosphere Model, and with and without the Rice Convection Model for inner magnetospheric drift physics. While both have been running for several years, nearly continuous results are available since July 2015. Dst from the model output is compared against the Kyoto real-time Dst. Various quantitative measures are presented to assess the goodness of fit between the models and observations. In particular, correlation coefficients, RMSE and prediction efficiency are calculated and discussed. In addition, contingency tables are presented, demonstrating the ability of the model to predict "disturbed times" as defined by Dst values below some critical threshold. It is shown that the SWMF run with the inner magnetosphere model is significantly better at reproducing storm-time values, with prediction efficiencies above 0.25 and Heidke skill scores above 0.5. This work was funded by NASA and NSF grants, and the European Union's Horizon 2020 research and innovation programme under grant agreement 637302 PROGRESS.

  9. Determinación de esteroles en la fracción insaponificable del aceite de los frutos de la palma real cubana (Roystonea regia Determination of sterols determination in unsaponifiable fraction from Cuban royal palm (Roystonea regia fruit oil

    Directory of Open Access Journals (Sweden)

    David Marrero Delange

    2013-03-01

    Full Text Available Introducción: los esteroles han sido ampliamente estudiados por su importancia nutricional y farmacéutica. Sin embargo, para nuestro conocimiento, la composición de esteroles del aceite de los frutos de la palma real cubana (Roystonea regia no ha sido determinada hasta el momento. Objetivos: determinar la composición de esteroles que pudieran estar presentes en la fracción insaponificable del aceite de R. regia mediante CG-EM. Métodos: muestras de dos lotes de aceite de R. regia fueron sometidas al procedimiento para la determinación de esteroles establecido por el del Instituto de Nutracéuticos de los EE.UU., el cual consiste, fundamentalmente, en una saponificación con disolución de KOH/EtOH y posterior extracción con n-hexano de las fracciones insaponificables. Las fracciones obtenidas fueron analizadas por CG-EM como derivados TMS e identificadas por comparación de sus espectros con los de patrones comerciales y los de la base de espectros Wiley. Para la cuantificación se utilizó el colestano como patrón interno. Resultados: en la fracción insaponificable del aceite de R. regia se encontró un contenido total de esteroles de 66,1%; lo que representa un 0,14 % del aceite. La fracción de esteroles, estuvo compuesta principalmente por â -sitosterol (51,2 %, estigmasterol (9,6 %, campesterol (9,2 %, 24-metilen-cicloartanol (9,2 %, Ä5-avenasterol (8,9 %, cicloartanol (7,5 %; además de otros componentes minoritarios como cicloartenol, ã-sitosterol y colesterol. Conclusiones: se identificaron y se cuantificaron mediante CG-EM los esteroles de la fracción insaponificable del aceite de R. regia, en la cual el â-sitosterol resultó el componente mayoritario. Estos resultados son una contribución al estudio de la composición química de dicho aceite y pudieran avalar su posible utilidad nutricional y seguridad.Introduction: sterols have been widely studied because of their pharmaceutical and nutritional importance. However, to

  10. Assessment of real exposure to GSM mobile telephones using the SYRPOM

    International Nuclear Information System (INIS)

    Picard, D.; Fouquet, L.; Chauvin, S.

    2013-01-01

    A mobile telephone user's exposure to the radio-frequency electromagnetic field depends heavily on the power their telephone radiates, which can vary widely according to requests from the base station. This study presents the design and development of a system called System for Radiated Power Measurement (SYRPOM), which measures the power radiated by a mobile telephone. This study also describes the tests carried out on the system itself and gives the results of two measuring campaigns it has been possible to perform in this way. The first such campaign consisted of assessing the mean power received by a typical mobile telephone user carrying out various activities. The second campaign was aimed at (1) comparing the mean radiated power when stationary and when moving and (2) assessing and contrasting different models of handsets in terms of the mean radiated power. The SYRPOM has proved to be a flexible, easy-to-use high-performance and innovative tool for carrying out this kind of studies. (authors)

  11. A study on the radiation and environmental safety -Development of a real-time radiological dose assessment system-

    Energy Technology Data Exchange (ETDEWEB)

    Han, Moon Heui; Lee, Yung Bok; Kim, Eun Han; Suh, Kyung Suk; Hwang, Won Tae [Korea Atomic Energy Research Institute, Taejon (Korea, Republic of)

    1995-07-01

    The real-time dose assessment system under development has been updated and the technology for tracer experiment has been established. The calculation of external gamma dose is the most difficult and time-consuming part of the dose calculations. The characteristics of external gamma exposure have been investigated and the method for reducing the calculation time has been devised. The internal exposure via the ingestion of the contaminated foodstuffs is one of the important pathways to the total radiological exposure. In the emergency, it is necessary to take an action such like food ban to protect the internal exposure. An algorithm for the interface between the real-time system and the food chain model has been provided. The second field tracer experiment over flat terrain has been carried out on a plain in Iksan city in Junrabook-Do. Sequential tracer sampler which can be sampled the tracer gas over arbitrary 12 time interval has been designed and manufactured. SF{sub 6} has been used as the tracer gas and the sampled gas has been analysed by gas-chromatographer. 55 figs, 32 tabs, 65 refs. (Author).

  12. Concentration measurement in a road tunnel as a method to assess "real-world" vehicles exhaust emissions

    Science.gov (United States)

    Zanini, G.; Berico, M.; Monforti, F.; Vitali, L.; Zambonelli, S.; Chiavarini, S.; Georgiadis, T.; Nardino, M.

    An experiment aimed at comparing particulate matter (PM) and polycyclic aromatic hydrocarbons (PAHs) concentrations produced in a road tunnel by buses is described. The experiment took place in 2001 in Bologna when a couple of buses belonging to the public transport fleet where driven backwards and forwards in a road tunnel closed to all other vehicles. Buses run in the tunnel for 8 h a day for 4 experiment days, each day using a different fuel: biodiesel, diesel-water emulsion, diesel-water emulsion with low sulphur content and commercial diesel. Average daily concentrations of PM of different sizes and of 12 PHAs were measured and comparison between different fuels was attempted in order to assess "real-world" exhaust emissions of different fuels. Due to heterogeneity of experimental conditions in different days and the relatively large measurement uncertainties, the effort was only partially successful, and it was not possible to state any firm conclusion on fuels reliability even if some indications in agreement with literature were found. Nevertheless, the experiment and the data analysis method developed could be of interest as a methodological approach for future experiments aimed at evaluating "real-world" exhaust emissions of single vehicles.

  13. Assessing the value of real-time snow and avalanche information

    Science.gov (United States)

    Zeidler, Antonia; Adams, Marc; Schuster, Martin; Berner, Martin; Nagy, Wilhelm

    2017-04-01

    This poster presentation shows first results from a pilot study on exploring the possibilities of using existing and new information and communication technologies (ICT) for snow and avalanche assessments. Today, ICT solutions allow the utilisation of information at a high spatiotemporal resolution, due to the widespread availability of internet access, high computing power and affordable mobile devices. Therefore, there is an increasing request for up to date information on snow and avalanche decision-making. However, there are challenges that need to be addressed from different view points. These include topics in the field of technological feasibility of providing a stable network, exchanging trustworthy information and motivation of experts to participate. This contribution discusses the lessons-learnt, from the establishment of a platform to the user-experience.

  14. Assessing the Sectoral Dynamics of Non-performing Loans: Signs from Financial and Real Economy

    Directory of Open Access Journals (Sweden)

    Bogdan MOINESCU

    2012-02-01

    Full Text Available The paper is an attempt at studying the mechanisms whereby the economic activity dynamics and money market conditions affect the developments in nonperforming loan ratio across the main activity sectors, namely agriculture, industry, commerce and constructions. The default rates are modeled both on the basis of a linear approach and via a logistic function, starting from the methodological solution of the reputed conditional risk model referred to as Credit Portfolio View. The robustness of the analytical framework is ensured by applying SUR estimation method for simultaneous systems of equations in combination with that of autoregressive vectors. The empirical analysis is based on unique set of quarterly data, which allows for assessing the quality of non-financial companies loan repayment. The relevant explanatory variables were used in various configurations and lags for constructing several macroeconomic credit risk models.

  15. Assessing air medical crew real-time readiness to perform critical tasks.

    Science.gov (United States)

    Braude, Darren; Goldsmith, Timothy; Weiss, Steven J

    2011-01-01

    Air medical transport has had problems with its safety record, attributed in part to human error. Flight crew members (FCMs) must be able to focus on critical safety tasks in the context of a stressful environment. Flight crew members' cognitive readiness (CR) to perform their jobs may be affected by sleep deprivation, personal problems, high workload, and use of alcohol and drugs. The current study investigated the feasibility of using a computer-based cognitive task to assess FCMs' readiness to perform their job. The FCMs completed a short questionnaire to evaluate their physiologic and psychological state at the beginning and end of each shift. The FCMs then performed 3 minutes of a computer-based cognitive task called synthetic work environment (SYNWIN test battery). Task performance was compared with the questionnaire variables using correlation and regression analysis. Differences between the beginning and end of each shift were matched and compared using a paired Students t test. SYNWIN performance was significantly worse at the end of a shift compared with the beginning of the shift (p = 0.028) primarily because of decrement in the memory component. The SYNWIN composite scores were negatively correlated to degree of irritability felt by the participant, both before (r = -0.25) and after (r = -0.34) a shift and were significantly correlated with amount of sleep (0.22), rest (0.30), and life satisfaction (0.30). Performance by FCMs on a simple, rapid, computer-based psychological test correlates well with self-reported sleep, rest, life satisfaction, and irritability. Although further studies are warranted, these findings suggest that assessment of the performance of FCMs on a simple, rapid, computer-based, multitasking battery is feasible as an approach to determine their readiness to perform critical safety tasks through the SYNWIN task battery.

  16. Real-Time Assessment of the Effect of Biofeedback Therapy with Migraine: A Pilot Study.

    Science.gov (United States)

    Odawara, Miyuki; Hashizume, Masahiro; Yoshiuchi, Kazuhiro; Tsuboi, Koji

    2015-12-01

    Biofeedback therapy has been reported to be effective in the treatment of migraine. However, previous studies have assessed its effectiveness using paper-and-pencil diaries, which are not very reliable. The objective of the present pilot study was to investigate the feasibility of using computerized ecological momentary assessment (EMA) for evaluating the efficacy of BF treatment for migraine in a randomized controlled trial. The subjects comprised one male and 26 female patients with migraine. They were randomly assigned to either biofeedback or wait-list control groups. Patients were asked to carry a palmtop-type computer to record momentary symptoms for 4 weeks before and after biofeedback treatment. The primary outcome measure was headache intensity. The secondary outcome measures included psychological stress, anxiety, irritation, headache-related disability and the frequency (number of days per month) of migraine attack and of headache of at least moderate intensity (pain rating ≥50). Headache intensity showed significant main effects of period (before vs. after therapy, p = 0.02) and group (biofeedback vs. control groups, p = 0.42) and a significant period × group interaction (p Biofeedback reduced the duration of headaches by 1.9 days, and the frequency of days when headache intensity was ≥50 by 2.4 times. In addition, headache-related disability, psychological stress, depression, anxiety, and irritation were significantly improved. The present study used computerized EMA to show that biofeedback could improve the symptoms of migraine, including psychological stress and headache-related disability.

  17. Real-time assessment of radiation burden of the population in the vicinity of nuclear power plants during radiation accidents

    International Nuclear Information System (INIS)

    Stubna, M.

    1986-01-01

    The method is presented of real-time calculation of the radiation situation (dose equivalents) in the environs of a nuclear power plant in case of an accident involving the release of radioactive substances into the atmosphere, this for the potentially most significant exposure paths in the initial and medium stages of the accident. The method allows to take into consideration the time dependence of the rate of radioactive substance release from the nuclear power plant and to assess the development in space and time of the radiation situation in the environs of the nuclear power plant. The use of the method is illustrated by an example of the calculation of the development of the radiation situation for model accidents of a hypothetical PWR with containment. (author)

  18. Numerical modeling in real-time assessment of dispersal of radionuclides beyond ten to twenty kilometres from an accidental release

    International Nuclear Information System (INIS)

    ApSimon, H.M.; Wilson, J.J.N.

    1990-01-01

    The Chernobyl accident has demonstrated the need for capabilities to assess transport and contamination out to considerable distances and across national frontiers in the event of a nuclear accident. For real-time assessment close to the source, the transport, dilution and deposition of material are usually based on simple Gaussian plume or puff techniques. At greater distances, usually beyond 10 or 20 km., changing meteorological conditions and topographical features become increasingly important and may require rather different modelling techniques. At yet longer distances synoptic scale weather patterns and their evolution govern where material will travel, and regions where precipitation may potentially yield higher deposition of critical nuclides such as I-131 and Cs-137. This paper will consider the questions to be addressed by numerical models during a nuclear emergency, and how such models may be incorporated in an overall assessment system for emergency procedures, extending to span the European Continent. The appropriate modelling techniques available for simulating transport over mesoscale distances (out to a few hundred kilometres), and for the synoptic scale (out to a few thousand kilometres) will be reviewed. The radiological measurements which would be of the greatest use for checking and revising model calculations in an emergency situation will also be discussed, and the importance of international exchange of such information emphasized

  19. 24-Hour Blood Pressure Variability Assessed by Average Real Variability: A Systematic Review and Meta-Analysis.

    Science.gov (United States)

    Mena, Luis J; Felix, Vanessa G; Melgarejo, Jesus D; Maestre, Gladys E

    2017-10-19

    Although 24-hour blood pressure (BP) variability (BPV) is predictive of cardiovascular outcomes independent of absolute BP levels, it is not regularly assessed in clinical practice. One possible limitation to routine BPV assessment is the lack of standardized methods for accurately estimating 24-hour BPV. We conducted a systematic review to assess the predictive power of reported BPV indexes to address appropriate quantification of 24-hour BPV, including the average real variability (ARV) index. Studies chosen for review were those that presented data for 24-hour BPV in adults from meta-analysis, longitudinal or cross-sectional design, and examined BPV in terms of the following issues: (1) methods used to calculate and evaluate ARV; (2) assessment of 24-hour BPV determined using noninvasive ambulatory BP monitoring; (3) multivariate analysis adjusted for covariates, including some measure of BP; (4) association of 24-hour BPV with subclinical organ damage; and (5) the predictive value of 24-hour BPV on target organ damage and rate of cardiovascular events. Of the 19 assessed studies, 17 reported significant associations between high ARV and the presence and progression of subclinical organ damage, as well as the incidence of hard end points, such as cardiovascular events. In all these cases, ARV remained a significant independent predictor ( P <0.05) after adjustment for BP and other clinical factors. In addition, increased ARV in systolic BP was associated with risk of all cardiovascular events (hazard ratio, 1.18; 95% confidence interval, 1.09-1.27). Only 2 cross-sectional studies did not find that high ARV was a significant risk factor. Current evidence suggests that ARV index adds significant prognostic information to 24-hour ambulatory BP monitoring and is a useful approach for studying the clinical value of BPV. © 2017 The Authors. Published on behalf of the American Heart Association, Inc., by Wiley.

  20. Living donor transplantation--the real gift of life. Procurement and the ethical assessment.

    Science.gov (United States)

    Banasik, Mirosław

    2006-01-01

    It has been observed during the past 10-15 years a greater disparity between the supply of kidneys for transplantation and the demand of patients on waiting lists. The number of cadaveric kidneys available for transplantation have not increased in many countries. Countries and their societies are faced with a choice, let patients with the end- stage renal disease stay on, dialysis giving a faster death and a lower quality of life, or decide to introduce the more active living donation program. There are countries, historically Scandinavian countries, the U.S.A. and U.K., which decided to change medical, social and ethical attitudes to help their citizens and patients on dialysis. For many other countries approval of the new approach of their donation seems to cause difficulties. The main problem for medical staff is the principle Primum non nocere (First do no harm), removal of a living kidney conflicts with this principle. From the other point of view is the human right of an individual to autonomy for donation of a kidney. The donor is completely informed for the risks involved in donation of a kidney to an awaiting recipient. The donors reasons for donation of the kidney must be understood and family pressure excluded. Where is the borderline between the paternalistic approach of the medical personnel preventing the altruistic attitude of the donor? How far is the role of the medical staff to extend in the assessment of the altruistic nature and goodwill of the donors?

  1. Evaluación de los caminos rurales: hacia un enfoque orientado al usuario. / Assessment of rural roads. Towards a user-oriented approach.

    Directory of Open Access Journals (Sweden)

    González, Sergio

    2000-03-01

    Full Text Available Este trabajo presente algunos resultados de un estudio piloto realizado para el IFRTD (Foro Internacional para el Transporte Rural y el Desarrollo, Londres sobre los temas de movilización y vialidad en la comuna de Canela, IV Región de Chile. El planteamiento es que una política coherente de vialidad rural debe tener como fundamento un entendimiento de las necesidades percibidas por las comunidades rurales y de las prioridades que expresan. Este tema se explora en el proyecto en forma preliminar utilizando metodologías cualitativas y cuantitativas para investigar las necesidades de movilización en diversas comunidades de Canela desde el punto de vista de los usuarios, operadores de transporte y autoridades locales. Se presentará un análisis de los resultados pertinentes al asunto de la vialidad, que pretende establecer de manera tentativa un perfil del usuario de los caminos rurales de la zona y las características de sus traslados más difíciles. Entre los resultados más significativos se destacan:Una percepción de los amplios efectos modernizadores que introduce la pavimentación de un camino de acceso al sector.La existencia de una correlación baja pero positiva entre la dificultad percibida por el usuario de su traslado y su evaluación del camino, que se ve relacionado con el modo de transporte que se ocupa.La conclusión principal del trabajo es que un conocimiento de los criterios propios con los cuales el usuario rural evalúa su traslado es necesario para una gestión exitosa de la vialidad rural./The author argues that a coherent policy for rural roads should be founded on the understanding of the perceived needs of rural communities and the priorities expressed. It describes the Methodological approaches to assess, in this way, rural roads.

  2. Ice crystallization in porous building materials: assessing damage using real-time 3D monitoring

    Science.gov (United States)

    Deprez, Maxim; De Kock, Tim; De Schutter, Geert; Cnudde, Veerle

    2017-04-01

    Frost action is one of the main causes of deterioration of porous building materials in regions at middle to high latitudes. Damage will occur when the internal stresses due to ice formation become larger than the strength of the material. Hence, the sensitivity of the material to frost damage is partly defined by the structure of the solid body. On the other hand, the size, shape and interconnection of pores manages the water distribution in the building material and, therefore, the characteristics of the pore space control potential to form ice crystals (Ruedrich et al., 2011). In order to assess the damage to building materials by ice crystallization, lot of effort was put into identifying the mechanisms behind the stress build up. First of all, volumetric expansion of 9% (Hirschwald, 1908) during the transition of water to ice should be mentioned. Under natural circumstances, however, water saturation degrees within natural rocks or concrete cannot reach a damaging value. Therefore, linear growth pressure (Scherer, 1999), as well as several mechanisms triggered by water redistribution during freezing (Powers and Helmuth, 1953; Everett, 1961) are more likely responsible for damage due to freezing. Nevertheless, these theories are based on indirect observations and models and, thus, direct evidence that reveals the exact damage mechanism under certain conditions is still lacking. To obtain this proof, in-situ information needs to be acquired while a freezing process is performed. X-ray computed tomography has proven to be of great value in material research. Recent advances at the Ghent University Centre for Tomography (UGCT) have already allowed to dynamically 3D image crack growth in natural rock during freeze-thaw cycles (De Kock et al., 2015). A great potential to evaluate the different stress build-up mechanisms can be found in this imaging technique consequently. It is required to cover a range of materials with different petrophysical properties to achieve

  3. Un gabinete numismático de la Ilustración española: la Real Sociedad Bascongada de los Amigos del País y Diego Lorenzo del Prestamero

    Directory of Open Access Journals (Sweden)

    Carlos ORTIZ DE URBINA MONTOYA

    2009-11-01

    Full Text Available RESUMEN: En las postrimerías del siglo XVIII, la pionera de la Sociedades Económicas fundadas en los territorios de la Corona borbónica española, la Real Sociedad Bascongada de los Amigos del País, establecería en Vitoria de la mano de su subsecretario, Diego Lorenzo del Prestamero, un gabinete numismático que se nutriría de las aportaciones de sus socios, tanto peninsulares como coloniales. La Guerra de la Convención, que daría lugar a la invasión y ocupación francesa de buena parte del territorio de Guipúzcoa y en última instancia de la ciudad de Vitoria, marcaría el punto de inflexión en la existencia de la Bascongada, y en consecuencia de sus actividades y, entre ellas, de su monetario. Adquirida por la Diputación Foral de Álava, esta colección numismática se encuentra en la actualidad depositada en el Palacio de Bendaña de Vitoria-Gasteiz a la espera de su ubicación definitiva.ABSTRACT: In the last years of of the 18th century, the pioneer of the economic societies established in the Spanish Bourbon kingdoms, the Real Sociedad Bascongada de Amigos del País, founded a numismatic collection in Vitoria, inspired by its under-secretary, Diego Lorenzo del Prestamero, and funded by the contributions of members in both the Peninsular and the colonies. The War of the Convention, that caused France to invade and occupy a large part of Guipúzcoa and eventually the city of Vitoria, marked the turning point in the existence of the Bascongada and, consequently, of its activities, including its numismatic activity. Acquired by the Leasehold Delegation (Diputación Foral of Álava, this numismatic collection is now in the Palace of Bendaña in Vitoria-Gasteiz, awaiting its definitive location.

  4. La recuperación de los elementos de piedra en el patrimonio arquitectónico monumental: el caso del claustro del convento de la Asunción de Calatrava de Almagro (Ciudad Real

    Directory of Open Access Journals (Sweden)

    Maldonado-Ramos, L.

    2014-12-01

    Full Text Available The cloister of Asunción de Calatravas’ Convent is one of the most important examples of Renaissance in Ciudad Real province. This paper compiles the explanation and summary of the intervention process in the stone elements of the cloister, based on a theoretical research about the type of stones in the area of analysis and the building as well as the most suitable techniques to restore them. Once the latter where selected, their adequation and compatibility was checked by on site tests. The paper has as main aim to divulge the methodology and the intervention, as well as to create a forum of debate about the restoration techniques for similar cases of Renaissance Architectural Heritage.El Claustro del Convento de la Asunción de Calatravas es uno de los ejemplos de arquitectura renacentista de mayor interés situados en la provincia de Ciudad Real. El presente artículo expone y resume el proceso de intervención llevado a cabo en los elementos pétreos del claustro, fundamentado en una investigación teórica sobre el tipo de material existente en la zona de estudio y en la edificación así como en las técnicas de intervención más adecuadas. Una vez seleccionadas éstas, su adecuación y compatibilidad se comprobó a partir de ensayos in situ desarrollados en áreas específicas de la intervención, extendiéndose posteriormente al resto de la actuación. El artículo pretende divulgar la metodología empleada así como la actuación llevada a cabo en dicha edificación y crear un foro de debate sobre las técnicas de actuación restauradora en casos similares de patrimonio arquitectónico renacentista.

  5. Task-oriented quality assessment and adaptation in real-time mission critical video streaming applications

    Science.gov (United States)

    Nightingale, James; Wang, Qi; Grecos, Christos

    2015-02-01

    In recent years video traffic has become the dominant application on the Internet with global year-on-year increases in video-oriented consumer services. Driven by improved bandwidth in both mobile and fixed networks, steadily reducing hardware costs and the development of new technologies, many existing and new classes of commercial and industrial video applications are now being upgraded or emerging. Some of the use cases for these applications include areas such as public and private security monitoring for loss prevention or intruder detection, industrial process monitoring and critical infrastructure monitoring. The use of video is becoming commonplace in defence, security, commercial, industrial, educational and health contexts. Towards optimal performances, the design or optimisation in each of these applications should be context aware and task oriented with the characteristics of the video stream (frame rate, spatial resolution, bandwidth etc.) chosen to match the use case requirements. For example, in the security domain, a task-oriented consideration may be that higher resolution video would be required to identify an intruder than to simply detect his presence. Whilst in the same case, contextual factors such as the requirement to transmit over a resource-limited wireless link, may impose constraints on the selection of optimum task-oriented parameters. This paper presents a novel, conceptually simple and easily implemented method of assessing video quality relative to its suitability for a particular task and dynamically adapting videos streams during transmission to ensure that the task can be successfully completed. Firstly we defined two principle classes of tasks: recognition tasks and event detection tasks. These task classes are further subdivided into a set of task-related profiles, each of which is associated with a set of taskoriented attributes (minimum spatial resolution, minimum frame rate etc.). For example, in the detection class

  6. Assessing the distribution of environmental stewardship organizations and their relationship to the demographics of Los Angeles County

    Science.gov (United States)

    Krystle M. Golly

    2017-01-01

    An equal distribution of environmental stewardship organizations across the urban landscape provides an environment that facilitates community empowerment. The systemic issues found in Los Angeles County play an important role in the social development of the area. Through the utilization of modern technology and geographical mapping software, spatial distribution of...

  7. Los comuneros del Socorro : II parte

    Directory of Open Access Journals (Sweden)

    Jorge Cárdenas García

    1979-02-01

    Full Text Available Como se dijo anteriormente, el 11 de mayo de 1781 los jefes comuneros ordenaron a los vencedores de Puente Real marchar sobre Tunja para que las autoridades y gentes de aquella jurisdicción se prepararan a emprender el camino hacia Santa Fe, última meta de los insurrectos.

  8. VALIDITATION OF A LIGHT QUESTIONNAIRE WITH REAL-LIFE PHOTOPIC ILLUMINANCE MEASUREMENTS: THE HARVARD LIGHT EXPOSURE ASSESSMENT QUESTIONNAIRE

    Science.gov (United States)

    Bajaj, Archna; Rosner, Bernard; Lockley, Steven; Schernhammer, Eva S.

    2011-01-01

    Background Light exposure at night is now considered a probable carcinogen. To study the effects of light on chronic diseases like cancer, methods to measure light exposure in large observational studies are needed. We aimed to investigate the validity of self-reported current light exposure. Methods We developed a self-administered semiquantitative light questionnaire, the Harvard Light Exposure Assessment (H-LEA) questionnaire, and compared photopic scores derived from this questionnaire with actual photopic and circadian measures obtained from a real-life 7-day light meter application among 132 women (85 rotating night shift workers and 47 day workers) participating in the Nurses' Health Study II. Results After adjustment for age, BMI, collection day, and night work status, the overall partial Spearman correlation between self-report of light exposure and actual photopic light measurements was 0.72 (P<0.001; Kendall τ =0.57) and 0.73 (P<0.0001; Kendall τ =0.58) when correlating circadian light measurements. There were only minimal differences in accuracy of self-report of light exposure and photopic or circadian light measurement between day (r=0.77 and 0.78, respectively) and rotating night shift workers (r=0.68 and 0.69, respectively). Conclusions The results of this study provide evidence of the criterion validity of self-reported light exposure using the H-LEA questionnaire. Impact: This questionnaire is a practical method of assessing light exposure in large scale epidemiologic studies. PMID:21737411

  9. Application of speckle image correlation for real-time assessment of metabolic activity in herpes virus-infected cells

    Science.gov (United States)

    Vladimirov, A. P.; Malygin, A. S.; Mikhailova, J. A.; Borodin, E. M.; Bakharev, A. A.; Poryvayeva, A. P.

    2014-09-01

    Earlier we reported developing a speckle interferometry technique and a device designed to assess the metabolic activity of a cell monolayer cultivated on a glass substrate. This paper aimed at upgrading the technique and studying its potential for real-time assessment of herpes virus development process. Speckle dynamics was recorded in the image plane of intact and virus-infected cell monolayer. HLE-3, L-41 and Vero cells were chosen as research targets. Herpes simplex virus-1-(HSV-1)- infected cell cultures were studied. For 24 h we recorded the digital value of optical signal I in one pixel and parameter η characterizing change in the distribution of the optical signal on 10 × 10-pixel areas. The coefficient of multiple determination calculated by η time dependences for three intact cell cultures equals 0.94. It was demonstrated that the activity parameters are significantly different for intact and virus-infected cells. The difference of η value for intact and HSV-1-infected cells is detectable 10 minutes from the experiment start.

  10. Application of speckle image correlation for real-time assessment of metabolic activity in herpes virus-infected cells

    International Nuclear Information System (INIS)

    Vladimirov, A P; Malygin, A S; Mikhailova, J A; Borodin, E M; Bakharev, A A; Poryvayeva, A P

    2014-01-01

    Earlier we reported developing a speckle interferometry technique and a device designed to assess the metabolic activity of a cell monolayer cultivated on a glass substrate. This paper aimed at upgrading the technique and studying its potential for real-time assessment of herpes virus development process. Speckle dynamics was recorded in the image plane of intact and virus-infected cell monolayer. HLE-3, L-41 and Vero cells were chosen as research targets. Herpes simplex virus-1-(HSV-1)- infected cell cultures were studied. For 24 h we recorded the digital value of optical signal I in one pixel and parameter η characterizing change in the distribution of the optical signal on 10 × 10-pixel areas. The coefficient of multiple determination calculated by η time dependences for three intact cell cultures equals 0.94. It was demonstrated that the activity parameters are significantly different for intact and virus-infected cells. The difference of η value for intact and HSV-1-infected cells is detectable 10 minutes from the experiment start.

  11. The TEX-I real-time expert system applied to situation assessment for the SNR-300 reactor

    International Nuclear Information System (INIS)

    Schmal, N.; Doerbecker, K.; Leder, H.J.; Rueckert, M.; Schade, H.J.

    1990-01-01

    Within the German TEX-I Project, which was sponsored by the Federal Ministry for Research and Technology, several companies developed industrial applications of technical expert systems for data interpretation, diagnosis and process control. The purpose of the diagnosis expert system reported here is to support the operators of the LMFBR SNR-300 in assessing plant status in real-time, based on readings from a large number of sensors. By online connection to the process control computer, it can monitor all incoming signal values, check the consistency of data, continuously diagnose the current plant status, detect unusual trends prior to accidents, localize faulty components and recommend operators response in abnormal conditions. The systems architecture consists of two basic subsystems, an inference engine and an intelligent process interface, implemented in Lisp on a Symbolics-Workstation. The inference engine has been derived from BABYLON, a hybrid shell developed by the German computer research institute GMD. This shell includes rules, prologue, constraints and an object oriented frame processor. The extended version has a component description language and a top-down diagnosis scheme including a mechanism of attention focusing. Inference run as independent, quasi-parallel processes. These so-called inference tasks can interrupt or abort each other, if higher priority events must be processed. The complete system is modelled in an object oriented matter and is divided into several subsystems and each subsystem into its physical components. At present the expert system is connected to a real-time simulation of the reactor. The simulation is based on a thermohydraulic code for simulation of the transient behaviour of temperatures and flow rates in the reactor core, plena, pipes, pumps, valves, intermediate heat exchangers and cooling components. Additionally, the systems response to an asynchronous operator interaction can be simulated. Several types of anomalies

  12. Performance and Quality Assessment of the Forthcoming Copernicus Marine Service Global Ocean Monitoring and Forecasting Real-Time System

    Science.gov (United States)

    Lellouche, J. M.; Le Galloudec, O.; Greiner, E.; Garric, G.; Regnier, C.; Drillet, Y.

    2016-02-01

    Mercator Ocean currently delivers in real-time daily services (weekly analyses and daily forecast) with a global 1/12° high resolution system. The model component is the NEMO platform driven at the surface by the IFS ECMWF atmospheric analyses and forecasts. Observations are assimilated by means of a reduced-order Kalman filter with a 3D multivariate modal decomposition of the forecast error. It includes an adaptive-error estimate and a localization algorithm. Along track altimeter data, satellite Sea Surface Temperature and in situ temperature and salinity vertical profiles are jointly assimilated to estimate the initial conditions for numerical ocean forecasting. A 3D-Var scheme provides a correction for the slowly-evolving large-scale biases in temperature and salinity.Since May 2015, Mercator Ocean opened the Copernicus Marine Service (CMS) and is in charge of the global ocean analyses and forecast, at eddy resolving resolution. In this context, R&D activities have been conducted at Mercator Ocean these last years in order to improve the real-time 1/12° global system for the next CMS version in 2016. The ocean/sea-ice model and the assimilation scheme benefit among others from the following improvements: large-scale and objective correction of atmospheric quantities with satellite data, new Mean Dynamic Topography taking into account the last version of GOCE geoid, new adaptive tuning of some observational errors, new Quality Control on the assimilated temperature and salinity vertical profiles based on dynamic height criteria, assimilation of satellite sea-ice concentration, new freshwater runoff from ice sheets melting …This presentation doesn't focus on the impact of each update, but rather on the overall behavior of the system integrating all updates. This assessment reports on the products quality improvements, highlighting the level of performance and the reliability of the new system.

  13. Flood Foresight: A near-real time flood monitoring and forecasting tool for rapid and predictive flood impact assessment

    Science.gov (United States)

    Revilla-Romero, Beatriz; Shelton, Kay; Wood, Elizabeth; Berry, Robert; Bevington, John; Hankin, Barry; Lewis, Gavin; Gubbin, Andrew; Griffiths, Samuel; Barnard, Paul; Pinnell, Marc; Huyck, Charles

    2017-04-01

    The hours and days immediately after a major flood event are often chaotic and confusing, with first responders rushing to mobilise emergency responders, provide alleviation assistance and assess loss to assets of interest (e.g., population, buildings or utilities). Preparations in advance of a forthcoming event are becoming increasingly important; early warning systems have been demonstrated to be useful tools for decision markers. The extent of damage, human casualties and economic loss estimates can vary greatly during an event, and the timely availability of an accurate flood extent allows emergency response and resources to be optimised, reduces impacts, and helps prioritise recovery. In the insurance sector, for example, insurers are under pressure to respond in a proactive manner to claims rather than waiting for policyholders to report losses. Even though there is a great demand for flood inundation extents and severity information in different sectors, generating flood footprints for large areas from hydraulic models in real time remains a challenge. While such footprints can be produced in real time using remote sensing, weather conditions and sensor availability limit their ability to capture every single flood event across the globe. In this session, we will present Flood Foresight (www.floodforesight.com), an operational tool developed to meet the universal requirement for rapid geographic information, before, during and after major riverine flood events. The tool provides spatial data with which users can measure their current or predicted impact from an event - at building, basin, national or continental scales. Within Flood Foresight, the Screening component uses global rainfall predictions to provide a regional- to continental-scale view of heavy rainfall events up to a week in advance, alerting the user to potentially hazardous situations relevant to them. The Forecasting component enhances the predictive suite of tools by providing a local

  14. Reflexiones sobre el Real Decreto español 171/2007, de 9 de febrero, por el que se regula la publicidad de los protocolos familiares en las sociedades familiares

    Directory of Open Access Journals (Sweden)

    María Angustias Díaz Gómez

    2011-06-01

    Full Text Available El objeto de este trabajo es analizar el Protocolo Familiar, estudiando su concepto, naturaleza jurídica y eficacia, su contenido, publicidad y desarrollo. El protocolo familiar es un instrumento jurídico que pretende organizar la relación entre la familia y la empresa, separando ambas realidades y, especialmente, trata de planificar adecuadamente la sucesión de la empresa familiar. Se trata de reflexionar sobre el Real Decreto español 171/2007, de 9 de febrero, por el que se regula la publicidad de los protocolos familiares en las Sociedades Familiares.The object of this work is to analyze the Family Protocol, studying his concept, juridical nature and effectiveness, his content, advertising and development. The family protocol is a legal instrument that, intends to organize the interaction between a family and their family-owned business, separating both realities and, specially, it tries to plan adequately the succession of the family business. It is a question of thinking about the Spanish Royal decree 171/2007, of February 9rd, by which there is regulated the advertising of the family protocols in the Familiar Companies.

  15. Evaluación de los estados emocionales de estudiantes de enfermería Assessment of the Nursing Students' Emotional States

    Directory of Open Access Journals (Sweden)

    João Luís Alves Apóstolo

    2007-06-01

    Full Text Available Fundamento: El estudio de los estados emocionales surge como problemática pertinente, en el contexto de la ayuda al desarrollo personal de los estudiantes y del aprendizaje construido. Objetivo: Analizar los estados emocionales de los estudiantes de la escuela de Enfermería de Coimbra, Portugal. Método: Estudio descriptivo-correlacional en una muestra de 229 estudiantes, en el que fueron aplicadas la Depression Anxiety and Stress Scale y la Positive and Negative Affect Schedule, una semana anterior al inicio de exámenes. Resultados: Aproximadamente 50% de los estudiantes presentaron niveles de ansiedad y de estrés superior al normal y 20%, niveles severos y extremamente severos. Aproximadamente 40 % de los estudiantes presentaron niveles de depresión superior al normal y 9% niveles severos y extremamente severos. Las mujeres presentaron promedios más altos de ansiedad, estrés y afectividad negativa. Discusión: Se verificó un elevado número de estudiantes revelando sufrimiento, diagnóstico que permitió definir una estrategia de intervención institucional en tres direcciones: valoración de estrategias de asesoría pedagógica utilizadas por los profesores; reorientación de estrategias de recepción a estudiantes de nuevo ingreso a la escuela y la creación de un consultorio de apoyo psico-pedagógico, que está ya en funcionamiento.Background: The study of the emotional states arises as a pertinent problematics, in the context of the help to the students’ personal development and of the built learning. Objective: To analyse the emotional states of the students drawn from the Nursing School of Coimbra, Portugal. Method: Descriptive-correlational study in a sample of 229 nursing students, in the week prior to the students’ final assessment. The Depression Anxiety and Stress Scale and the Positive and Negative Affect Schedule were used. Results: Approximately 50% of the students present levels of anxiety and stress above the

  16. Program management assessment of Federal Facility Compliance Agreement regarding CAA-40 C.F.R. Part 61, Subpart H at the Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    1997-01-01

    An assessment of Los Alamos National Laboratory's management system related to facility compliance with an element of the Clean Air Act was performed under contract by a team from Northern Arizona University. More specifically, a Federal Facilities Compliance Agreement (FFCA) was established in 1996 to bring the Laboratory into compliance with emissions standards of radionuclides, commonly referred to as Rad/NESHAP. In the fall of 1996, the four-person team of experienced environmental managers evaluated the adequacy of relevant management systems to implement the FFCA provisions. The assessment process utilized multiple procedures including document review, personnel interviews and re-interviews, and facility observations. The management system assessment was completed with a meeting among team members, Laboratory officials and others on November 1, 1996 and preparation of an assessment report

  17. Los insomnios

    OpenAIRE

    Takeuchi Tan, Yuri; Fundación Valle de Lili

    1998-01-01

    Los insomnios/El sueño normal/Otros trastornos de sueño que producen insomnio pero también hipersomnio (excesiva somnolencia diurna)/Manejo y tratamiento de los insomnios/Higiene del sueño/Instrucciones para la higiene del sueño/Técnicas conductuales/Terapia farmacológica.

  18. Real-Time Assessment of Fatigue in Patients With Multiple Sclerosis: How Does It Relate to Commonly Used Self-Report Fatigue Questionnaires?

    Science.gov (United States)

    Heine, Martin; van den Akker, Lizanne Eva; Blikman, Lyan; Hoekstra, Trynke; van Munster, Erik; Verschuren, Olaf; Visser-Meily, Anne; Kwakkel, Gert

    2016-11-01

    (1) To assess real-time patterns of fatigue; (2) to assess the association between a real-time fatigue score and 3 commonly used questionnaires (Checklist Individual Strength [CIS] fatigue subscale, Modified Fatigue Impact Scale (MFIS), and Fatigue Severity Scale [FSS]); and (3) to establish factors that confound the association between the real-time fatigue score and the conventional fatigue questionnaires in patients with multiple sclerosis (MS). Cross-sectional study. MS-specialized outpatient facility. Ambulant patients with MS (N=165) experiencing severe self-reported fatigue. Not applicable. A real-time fatigue score was assessed by sending participants 4 text messages on a particular day (How fatigued do you feel at this moment?; score range, 0-10). Latent class growth mixed modeling was used to determine diurnal patterns of fatigue. Regression analyses were used to assess the association between the mean real-time fatigue score and the CIS fatigue subscale, MFIS, and FSS. Significant associations were tested for candidate confounders (eg, disease severity, work status, sleepiness). Four significantly different fatigue profiles were identified by the real-time fatigue score, namely a stable high (n=79), increasing (n=57), stable low (n=16), and decreasing (n=13). The conventional questionnaires correlated poorly (rquestionnaires, ranging from 15.4% to 35%. Perceived fatigue showed 4 different diurnal patterns in patients with MS. Severity of sleepiness is an important confounder to take into account in the assessment of fatigue. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  19. REAL INTAKE AND PROVISION WITH VITAMINS AND CALCIUM IN OSTEOPOROSIS: ASSESSMENT BY MEASURING INTAKE AND PLASMA CONCENTRATIONS

    Directory of Open Access Journals (Sweden)

    V. N. Khodyrev

    2014-01-01

    Full Text Available Aim:  To assess the providing an organism with vitamins (А, В2, С, Е, β-carotene, and calcium in osteoporosis patients by measuring their intake and plasma concentrations. Materials and methods: 108 pairs “osteoporosis patient – healthy volunteer” aged 64.29±9.73 years were formed using a “case-control” method. Real intake of vitamins and calcium was studied defining the frequency of food taking for a month using questionnaire method. Daily intake of vitamins А, В2, С, Е, β-carotene, and calcium was calculated based on the analysis of the frequency of food taking. Among the basic group, using randomized method, 60% of osteoporosis patients were selected who underwent definition of plasma levels of vitamins А, В2, С, and Е. The same study was performed in 60 control volunteers. Results: Correlation of the intake of vitamins A, C, and β-carotene with their plasma levels wasn’t noted. It may reveal an increased need in these nutrients in osteoporosis. According to the calcium intake, every osteoporosis patient can be attributed to a population category with deep insufficiency of calcium intake (less than 500 mg a day. Conclusion: The data obtained need further investigation and, first of all, in clinical and biochemical fields (enzymatic non-provision for calcium uptake, clinical manifestations of insufficient provision with nutrients. Solution of these problems would enable regulation of food intake concerning calcium uptake in osteoporosis.

  20. A system for real-time environmental assessment using an operational meteorological data base for dispersion calculations

    International Nuclear Information System (INIS)

    Appelgren, A.; Hallberg, B.; Nordlinder, S.; Salomonsson, S.

    1990-01-01

    A method for assessing the meteorological conditions on a local scale, about 20 km, around a specific site was developed, and applied to the area around the Forsmark nuclear power plant, situated on the coast about 100 km north of Stockholm. Meteorological data were collected, for an one-year period, from sensors in a tower and from a Sodar system at Forsmark. In addition, two Sodar systems were placed at several locations around the power plant, out to a distance of approximately 20 km. By statistical compiling, an operational data base was established, consisting of classes of wind speed, wind direction and atmospheric stability. The data from the remote sites were related to those from Forsmark. This gave the possibility to determine the variation of the meteorological conditions in time and space, using data from a single location only. The main objective of the Forsmark project was to identify and indicate situations in which the conditions for dispersion were difficult to model accurately when using measurements taken from a conventional tower, without knowledge of the influence of local mesoscale disturbances. Such could be e.g. sea breeze, large horizontal or vertical wind shear, terrain-induced flow patterns etc. The use of an operational data base, as described above, in connection with real-time dispersion models, such as AIRPAC/EMMA, will improve the performance of such models, as well as consequence analyses, in case of accidental releases from nuclear power plants or other industrial plants

  1. Ambient mass spectrometry employing direct analysis in real time (DART) ion source for olive oil quality and authenticity assessment

    International Nuclear Information System (INIS)

    Vaclavik, Lukas; Cajka, Tomas; Hrbek, Vojtech; Hajslova, Jana

    2009-01-01

    A novel approach for the authentication of olive oil samples representing different quality grades has been developed. A new type of ion source, direct analysis in real time (DART), coupled to a high-resolution time-of-flight mass spectrometer (TOFMS) was employed for the comprehensive profiling of triacylglycerols (TAGs) and/or polar compounds extracted with a methanol-water mixture. The main parameters influencing the ionization efficiency of TAGs were the type of sample solvent, degree of sample dilution, ion beam temperature, and presence of a dopant (ammonia vapors). The ionization yield of polar compounds depended mainly on a content of water in the extract and ion beam temperature. Using DART-TOFMS, not only differentiation among extra virgin olive oil (EVOO), olive pomace oil (OPO) and olive oil (OO) could be easily achieved, but also EVOO adulteration with commonly used adulterant, hazelnut oil (HO), was feasible. Based on the linear discriminant analysis (LDA), the introduced method allowed detection of HO addition of 6 and 15% (v/v) when assessing DART-TOFMS mass profiles of polar compounds and TAGs, respectively.

  2. Ambient mass spectrometry employing direct analysis in real time (DART) ion source for olive oil quality and authenticity assessment

    Energy Technology Data Exchange (ETDEWEB)

    Vaclavik, Lukas; Cajka, Tomas; Hrbek, Vojtech [Institute of Chemical Technology Prague, Faculty of Food and Biochemical Technology, Department of Food Chemistry and Analysis, Technicka 5, 166 28 Prague 6 (Czech Republic); Hajslova, Jana, E-mail: jana.hajslova@vscht.cz [Institute of Chemical Technology Prague, Faculty of Food and Biochemical Technology, Department of Food Chemistry and Analysis, Technicka 5, 166 28 Prague 6 (Czech Republic)

    2009-07-10

    A novel approach for the authentication of olive oil samples representing different quality grades has been developed. A new type of ion source, direct analysis in real time (DART), coupled to a high-resolution time-of-flight mass spectrometer (TOFMS) was employed for the comprehensive profiling of triacylglycerols (TAGs) and/or polar compounds extracted with a methanol-water mixture. The main parameters influencing the ionization efficiency of TAGs were the type of sample solvent, degree of sample dilution, ion beam temperature, and presence of a dopant (ammonia vapors). The ionization yield of polar compounds depended mainly on a content of water in the extract and ion beam temperature. Using DART-TOFMS, not only differentiation among extra virgin olive oil (EVOO), olive pomace oil (OPO) and olive oil (OO) could be easily achieved, but also EVOO adulteration with commonly used adulterant, hazelnut oil (HO), was feasible. Based on the linear discriminant analysis (LDA), the introduced method allowed detection of HO addition of 6 and 15% (v/v) when assessing DART-TOFMS mass profiles of polar compounds and TAGs, respectively.

  3. The design of a miniature personal exposure monitor for continuous real-time data acquisition in electromagnetic field exposure assessment

    International Nuclear Information System (INIS)

    Hansen, N.H.; Conroy, T.J.; Wilson, B.W.

    1994-06-01

    The design of a small, light-weight personal exposure monitor suitable for use in EMF exposure assessment studies is nearing completion at Pacific Northwest Laboratory. The monitor is designed to be non-obtrusive, battery operated, and able to continuously record extremely low-frequency (ELF) (1Ohz--500hz) magnetic-field data. It also captures high-frequency (500hz--1OMhz) transients that exceed a preset threshold, retaining the largest transients in memory. The monitor can record one or more days of data on a single easily replaceable, credit-card-size memory (PCMCIA). A battery charge will last a minimum of one day. Batteries are rechargeable and easily replaced. A data-compression algorithm is under development that will be tailored to the efficient compression of low-frequency EMF signals and will permit data to be logged for at least one day before swapping memory cards. The memory cards are readable by a base- station computer that can perform analysis of the data. The monitor is designed to accommodate four inputs supporting full-field sensors as well as a proposed ocular exposure measurement system. Our design effort has shown that a practical personal exposure monitor for EMF can be built based on current technology, continuous logging of real-time ELF waveforms is both feasible and practical, and such a device is appropriate for proposed EMF exposure studies

  4. Real Patient and its Virtual Twin: Application of Quantitative Systems Toxicology Modelling in the Cardiac Safety Assessment of Citalopram.

    Science.gov (United States)

    Patel, Nikunjkumar; Wiśniowska, Barbara; Jamei, Masoud; Polak, Sebastian

    2017-11-27

    A quantitative systems toxicology (QST) model for citalopram was established to simulate, in silico, a 'virtual twin' of a real patient to predict the occurrence of cardiotoxic events previously reported in patients under various clinical conditions. The QST model considers the effects of citalopram and its most notable electrophysiologically active primary (desmethylcitalopram) and secondary (didesmethylcitalopram) metabolites, on cardiac electrophysiology. The in vitro cardiac ion channel current inhibition data was coupled with the biophysically detailed model of human cardiac electrophysiology to investigate the impact of (i) the inhibition of multiple ion currents (I Kr , I Ks , I CaL ); (ii) the inclusion of metabolites in the QST model; and (iii) unbound or total plasma as the operating drug concentration, in predicting clinically observed QT prolongation. The inclusion of multiple ion channel current inhibition and metabolites in the simulation with unbound plasma citalopram concentration provided the lowest prediction error. The predictive performance of the model was verified with three additional therapeutic and supra-therapeutic drug exposure clinical cases. The results indicate that considering only the hERG ion channel inhibition of only the parent drug is potentially misleading, and the inclusion of active metabolite data and the influence of other ion channel currents should be considered to improve the prediction of potential cardiac toxicity. Mechanistic modelling can help bridge the gaps existing in the quantitative translation from preclinical cardiac safety assessment to clinical toxicology. Moreover, this study shows that the QST models, in combination with appropriate drug and systems parameters, can pave the way towards personalised safety assessment.

  5. PRÁCTICAS EVALUATIVAS DE LOS DOCENTES EN CHILE: UNA REALIDAD IN SITU / ASSESSMENT PRACTICES OF TEACHERS IN CHILE: A REALITY IN SITU

    Directory of Open Access Journals (Sweden)

    Alicia Zambrano

    2016-11-01

    Full Text Available La evaluación es fundamental para mejorar la calidad de la enseñanza. Es una actividad compleja y exige un trabajo colaborativo, reflexión y organización; su desarrollo resulta fundamental para la mejora y la innovación de todos los ámbitos educativos: sistemas, programas, servicios, profesores y estudiantes. Desde la evaluación se orienta la actividad educativa de tal forma que los sujetos se ven condicionados no sólo a partir de los resultados surgidos en las evaluaciones sino a partir de la focalización y determinación de los elementos y objetos sobre lo que ejercerá su realidad (Mateo, 2000. El principal objetivo de esta investigación ha sido caracterizar y analizar el proceso evaluativo que llevan a cabo los docentes de Educación General Básica de la administración de tipo municipal de una comuna al sur de Chile. El mismo parte del diseño y construcción de un cuestionario exploratorio sobre la evaluación del aprendizaje y entrevista semiestructurada sobre el proceso evaluativo, aplicados a profesores de educación general básica, en forma presencial. Con las respuestas aportadas se describen e interpretan los procesos evaluativos que desarrollan los docentes; se destaca la importancia y los efectos posteriores coherentes con los principios de la Reforma Educacional y la ley de Sistema Nacional de Aseguramiento de la Calidad. Los resultados reflejaron que los docentes desarrollan procesos evaluativos más tradicionales para evaluar, con un énfasis exclusivo en el estudiante y confirmaron que aquellos docentes que otorgan una mayor importancia a la evaluación desarrollan buenas prácticas evaluativas. El estudio demuestra que las buenas prácticas evaluativas no inciden en el porcentaje de aprobación del estudiante. De igual modo, constata que la conceptualización sobre evaluación que tiene el docente incide en la percepción de buenas prácticas evaluativas. Finalmente, los docentes con niveles competenciales altos no

  6. Los Cactos

    Directory of Open Access Journals (Sweden)

    García Paredes Antonio

    1942-12-01

    Full Text Available El Cacto Cactus es uno de los géneros de plantas de la familia de las Cacteas Nopaleas que contiene muchas especies y variedades todas de formas extrañas, propias de la América intertropical y que habitan en los climas fríos y templados, en terrenos secos y estériles, desde el norte de Méjico hasta la Patagonia. Algunos cactos se cultivan por sus frutos que son sanosy sabrosos, otros como plantas ornamentales en los parques y jardines, otros como auxiliares para la industria, como los nopales en los que se cría la Cochinilla, insecto de la familia de los Hemípteros que produce la laca o carmín, materia colorante indispensable en la pintura al óleo y la acuarela, y por último, hoy están en moda y se cultivan con esmero una gran variedad de diminutos cactos exóticosque se mantienen sobre arena húmeda en pequeñas maceteras de porcelana, en los lugares más visibles de las habitaciones.

  7. Can virtual reality exposure therapy gains be generalized to real-life? A meta-analysis of studies applying behavioral assessments.

    Science.gov (United States)

    Morina, Nexhmedin; Ijntema, Hiske; Meyerbröker, Katharina; Emmelkamp, Paul M G

    2015-11-01

    In virtual reality exposure therapy (VRET), patients are exposed to virtual environments that resemble feared real-life situations. The aim of the current study was to assess the extent to which VRET gains can be observed in real-life situations. We conducted a meta-analysis of clinical trials applying VRET to specific phobias and measuring treatment outcome by means of behavioral laboratory tests or recordings of behavioral activities in real-life. Data sources were searches of databases (Medline, PsycInfo, and Cochrane). We included in total 14 clinical trials on specific phobias. Results revealed that patients undergoing VRET did significantly better on behavioral assessments following treatment than before treatment, with an aggregated uncontrolled effect size of g = 1.23. Furthermore, patients undergoing VRET performed better on behavioral assessments at post-treatment than patients on wait-list (g = 1.41). Additionally, results of behavioral assessment at post-treatment and at follow-up revealed no significant differences between VRET and exposure in vivo (g = -0.09 and 0.53, respectively). Finally, behavioral measurement effect sizes were similar to those calculated from self-report measures. The findings demonstrate that VRET can produce significant behavior change in real-life situations and support its application in treating specific phobias. Copyright © 2015 Elsevier Ltd. All rights reserved.

  8. Analysis of water availability from Son Real and Binicaubell torrents (Mallorca-Spain) for use in the artificial recharge of the La Marineta aquifer; Analisis de las disponibilidades hidricas de los torrentes de Son Real y Binicaubell (Mallorca-Espana) para su utilizacion en la recarga artificial del acuifero de la Marineta

    Energy Technology Data Exchange (ETDEWEB)

    Murillo, J. M.; Orden, J. A. de la; Gavilan, C. J.

    2009-07-01

    The history of artificial recharge of groundwater in Majorca island is explained in this paper. Too, a brief description of the only experience now working is shown, and an overview of the proposal of the Hydrogeological Plan of the Demarcation of Baleares for the regulation of runoff by means of the artificial recharge of aquifers is presented. This should include Son Real and Binicaubell torrents; so, an assessment of their water surpluses to determine water availability for artificial recharge is analyzed. The methodology used is based on a climatic analysis in the studied basins, as well as on the Son Real y Binicaubell torrents water inflow.Water naturally infiltrated through these torrents' beds and surpluses flowing to the sea are also quantified. The statistical analysis involves methods such as autocorrelation. (Author) 20 refs.

  9. A theoretical study for the real-time assessment of external gamma exposure using equivalent-volume numerical integration

    International Nuclear Information System (INIS)

    Han, Moon Hee

    1995-02-01

    An approximate method for estimating gamma external dose due to an arbitrary distribution of radioactive material has been developed. For the assessment of external gamma dose, the space over which radioactive material is distributed has been assumed to be composed of hexagonal cells. The evaluation of three-dimensional integration over the space is an extremely time-consuming task. Hence, a different approach has been used for the study, i.e., a equivalent-volume spherical approach in which a regular hexahedron is modeled as a equivalent-volume sphere to simplify the integration. For the justification of the current approach, two case studies have been performed: a comparison with a point source approximation and a comparison of external dose rate with the Monte Carlo integration. These comparisons show that the current approach gives reasonable results in a physical sense. Computing times of the developed and Monte Carlo integration method on VAX system have been compared as a function of the number of hexagonal cells. This comparison shows that CPU times for both methods are comparable in the region of small number of cells, but in the region of large number, Monte Carlo integration needs much more computing times. The proposed method is shown to have an accuracy equivalent to Monte Carlo method with an advantage of much shorter calculation time. Then, the method developed here evaluates early off-site consequences of a nuclear accident. An accident consequence assessment model has been integrated using Gaussian puff model which is used to obtain the distribution of radioactive material in the air and on the ground. For this work, the real meteorological data measured at Kori site for 10 years (1976 - 1985) have been statistically analyzed for obtaining site-specific conditions. The short-term external gamma exposures have been assessed for several site-specific meteorological conditions. The results show that the extent and the pattern of short-term external

  10. The potential of clustering methods to define intersection test scenarios: Assessing real-life performance of AEB.

    Science.gov (United States)

    Sander, Ulrich; Lubbe, Nils

    2018-04-01

    Intersection accidents are frequent and harmful. The accident types 'straight crossing path' (SCP), 'left turn across path - oncoming direction' (LTAP/OD), and 'left-turn across path - lateral direction' (LTAP/LD) represent around 95% of all intersection accidents and one-third of all police-reported car-to-car accidents in Germany. The European New Car Assessment Program (Euro NCAP) have announced that intersection scenarios will be included in their rating from 2020; however, how these scenarios are to be tested has not been defined. This study investigates whether clustering methods can be used to identify a small number of test scenarios sufficiently representative of the accident dataset to evaluate Intersection Automated Emergency Braking (AEB). Data from the German In-Depth Accident Study (GIDAS) and the GIDAS-based Pre-Crash Matrix (PCM) from 1999 to 2016, containing 784 SCP and 453 LTAP/OD accidents, were analyzed with principal component methods to identify variables that account for the relevant total variances of the sample. Three different methods for data clustering were applied to each of the accident types, two similarity-based approaches, namely Hierarchical Clustering (HC) and Partitioning Around Medoids (PAM), and the probability-based Latent Class Clustering (LCC). The optimum number of clusters was derived for HC and PAM with the silhouette method. The PAM algorithm was both initiated with random start medoid selection and medoids from HC. For LCC, the Bayesian Information Criterion (BIC) was used to determine the optimal number of clusters. Test scenarios were defined from optimal cluster medoids weighted by their real-life representation in GIDAS. The set of variables for clustering was further varied to investigate the influence of variable type and character. We quantified how accurately each cluster variation represents real-life AEB performance using pre-crash simulations with PCM data and a generic algorithm for AEB intervention. The

  11. Quistes de los maxilares

    Directory of Open Access Journals (Sweden)

    Ivan Alberto Manotas Arevalo

    2013-12-01

    Full Text Available Los Grandes Quistes de los Maxilares han estado vinculados siempre a la humanidad, desde tiempos remotos, pues han sido halladas en restos de especimenes fosiles, han llamado la atencion de los clínicos, en torno a su etiologia, en la que se ha introducido la participacion de la genetica, (demostrada en el desarrollo de los queratoquistes maxilares, la fisiopatologia, caracteristicas histologicas (inmunohistoquimica, posibilidades diagnosticas por la imagen, (como la tomografia computarizada y la resonancia nuclear magnetica y otras pruebas. Además llaman la atención al estudio, por sus alternativas de manejo especialmente las formas radicales, y el analisis de asociaciones a otras patolo-gias benignas y malignas, y de la recurrencia muy alto de algunas de estas lesiones. Mucho se ha desarrollado para elucidar su naturaleza real, estadificar adecuadamente la lesion descartando asocia-ciones patologicas sindromicas, indicar un tratamiento apropiado, y realizar seguimientos a largo plazo. Este articulo pretende recaudar una information general que de parametros para abordar el estudio de los quistes maxilares a partir de la presentacion de un caso clinico.

  12. Un análisis formal sobre los Llibres del Compte, de Reebudes i de Dades de la Procuración Real del Reino de Mallorca (1310-30

    Directory of Open Access Journals (Sweden)

    Maria Llompart Bibiloni

    2007-12-01

    Por un lado los Llibres del Compte, de Dades i de Reebudes al tener como finalidad la determinación de un saldo a entregar al Rey superan los simples libros registros, presentando características de la partida simple avanzada e incluso con indicios de partida doble. El método contable utilizado parece similar al de los comerciantes y banqueros italianos de la época, como la sociedad familiar florentina de los Peruzzi, quienes asimismo destinaban en sus libros, la primera mitad aproximada a los debes y la segunda mitad de páginas a los haberes. Y además de su importancia en el campo de la Historia de la Contabilidad en España, son una fuente inmejorable de datos económicos de la época.

  13. Virtual chromoendoscopy for the real-time assessment of colorectal polyps in vivo: a systematic review and economic evaluation.

    Science.gov (United States)

    Picot, Joanna; Rose, Micah; Cooper, Keith; Pickett, Karen; Lord, Joanne; Harris, Petra; Whyte, Sophie; Böhning, Dankmar; Shepherd, Jonathan

    2017-12-01

    Current clinical practice is to remove a colorectal polyp detected during colonoscopy and determine whether it is an adenoma or hyperplastic by histopathology. Identifying adenomas is important because they may eventually become cancerous if untreated, whereas hyperplastic polyps do not usually develop into cancer, and a surveillance interval is set based on the number and size of adenomas found. Virtual chromoendoscopy (VCE) (an electronic endoscopic imaging technique) could be used by the endoscopist under strictly controlled conditions for real-time optical diagnosis of diminutive (≤ 5 mm) colorectal polyps to replace histopathological diagnosis. To assess the clinical effectiveness and cost-effectiveness of the VCE technologies narrow-band imaging (NBI), flexible spectral imaging colour enhancement (FICE) and i-scan for the characterisation and management of diminutive (≤ 5 mm) colorectal polyps using high-definition (HD) systems without magnification. Systematic review and economic analysis. People undergoing colonoscopy for screening or surveillance or to investigate symptoms suggestive of colorectal cancer. NBI, FICE and i-scan. Diagnostic accuracy, recommended surveillance intervals, health-related quality of life (HRQoL), adverse effects, incidence of colorectal cancer, mortality and cost-effectiveness of VCE compared with histopathology. Electronic bibliographic databases including MEDLINE, EMBASE, The Cochrane Library and Database of Abstracts of Reviews of Effects were searched for published English-language studies from inception to June 2016. Bibliographies of related papers, systematic reviews and company information were screened and experts were contacted to identify additional evidence. Systematic reviews of test accuracy and economic evaluations were undertaken in accordance with the Preferred Reporting Items for Systematic Reviews and Meta-Analyses statement. Meta-analyses were conducted, where possible, to inform the independent

  14. los aprendizajes

    Directory of Open Access Journals (Sweden)

    Graciela Pérez Rivera

    2007-01-01

    Full Text Available En este documento se presentan algunos resultados, obtenidos hasta el momento, de un estudio sobre las prácticas de evaluación de profesores universitarios. El propósito del estudio es participar en la búsqueda de las relaciones existentes entre los conceptos y las prácticas educativas, en este caso de evaluación. Se identifican las principales tendencias en cuanto a la concepción de la evaluación del aprendizaje y las funciones que se le otorgan, los propósitos con los que se evalúa, los objetos o contenidos a evaluar, las formas en que se lleva a cabo la evaluación y el uso que se da a los resultados. Identificar cuáles son las tendencias de las prácticas de evaluación en nuestras aulas universitarias representa un paso que puede ayudar a cuidar que este proceso tan importante recobre su papel formativo para todos aquellos quienes participamos en los procesos educativos; además, representa la posibilidad de construir formas para lograr mejorar nuestra labor docente en general, y en particular, nuestra práctica evaluativa.

  15. The advantages of live/real time three-dimensional transesophageal echocardiography during assessments of pulmonary stenosis.

    Science.gov (United States)

    Kemaloğlu Öz, Tuğba; Özpamuk Karadeniz, Fatma; Akyüz, Şükrü; Ünal Dayı, Şennur; Esen Zencirci, Aycan; Atasoy, Işıl; Ösken, Altuğ; Eren, Mehmet

    2016-04-01

    This report sought to compare live/real-time three-dimensional transesophageal echocardiography (3D-TEE) with two-dimensional transesophageal echocardiography (2D-TEE) and to determine whether there are advantages to using 3D-TEE on patients with pulmonary stenosis (PS). Sixteen consecutive adult patients (50 % male and 50 % female; mean age 33 ± 13.4 years) with PS and indications of TEE were prospectively enrolled in this study. Following this, initial 2D-TEE and 3D-TEE examinations were performed, and 3D-TEE images were analyzed using an off-line Q-lab software system. Finally, the 2D-TEE and 3D-TEE findings were compared. In the present study, 3D-TEE allowed us to obtain the en face views of pulmonary valves (PVs) in all but one patient. While this patient was without a PV due to a previous tetralogy of Fallot operation, we could detect the type of PV in the other 15 (93.7 %) patients by using 3D-TEE. Due to poor image quality, the most stenotic area was not measurable in only one (6.2 %) of the patients. In eight (50 %) of the patients, severity and localization of stenosis were more precisely determined with 3DTEE than with 2D-TEE. The PVs' maximal annulus dimensions were found to be significantly larger when they were measured using 3D modalities. This study provides evidence of the incremental value of using 3D-TEE rather than 2D-TEE during assessments of PS, specifically in cases where special conditions (pregnancy, pulmonary regurgitation, and concomitant atrial septal defects) cause recordings of the transvalvular peak gradient to be inaccurate. Therefore, 3D-TEE should be used as a complementary imaging tool to 2D-TEE during routine echocardiographic examinations.

  16. Comparative Analysis of Dynamic Cell Viability, Migration and Invasion Assessments by Novel Real-Time Technology and Classic Endpoint Assays

    Science.gov (United States)

    Limame, Ridha; Wouters, An; Pauwels, Bea; Fransen, Erik; Peeters, Marc; Lardon, Filip; De Wever, Olivier; Pauwels, Patrick

    2012-01-01

    Background Cell viability and motility comprise ubiquitous mechanisms involved in a variety of (patho)biological processes including cancer. We report a technical comparative analysis of the novel impedance-based xCELLigence Real-Time Cell Analysis detection platform, with conventional label-based endpoint methods, hereby indicating performance characteristics and correlating dynamic observations of cell proliferation, cytotoxicity, migration and invasion on cancer cells in highly standardized experimental conditions. Methodology/Principal Findings Dynamic high-resolution assessments of proliferation, cytotoxicity and migration were performed using xCELLigence technology on the MDA-MB-231 (breast cancer) and A549 (lung cancer) cell lines. Proliferation kinetics were compared with the Sulforhodamine B (SRB) assay in a series of four cell concentrations, yielding fair to good correlations (Spearman's Rho 0.688 to 0.964). Cytotoxic action by paclitaxel (0–100 nM) correlated well with SRB (Rho>0.95) with similar IC50 values. Reference cell migration experiments were performed using Transwell plates and correlated by pixel area calculation of crystal violet-stained membranes (Rho 0.90) and optical density (OD) measurement of extracted dye (Rho>0.95). Invasion was observed on MDA-MB-231 cells alone using Matrigel-coated Transwells as standard reference method and correlated by OD reading for two Matrigel densities (Rho>0.95). Variance component analysis revealed increased variances associated with impedance-based detection of migration and invasion, potentially caused by the sensitive nature of this method. Conclusions/Significance The xCELLigence RTCA technology provides an accurate platform for non-invasive detection of cell viability and motility. The strong correlations with conventional methods imply a similar observation of cell behavior and interchangeability with other systems, illustrated by the highly correlating kinetic invasion profiles on different

  17. Assessing the interactivity and prescriptiveness of faculty professional development workshops: The real-time professional development observation tool

    Science.gov (United States)

    Olmstead, Alice; Turpen, Chandra

    2016-12-01

    Professional development workshops are one of the primary mechanisms used to help faculty improve their teaching, and draw in many STEM instructors every year. Although workshops serve a critical role in changing instructional practices within our community, we rarely assess workshops through careful consideration of how they engage faculty. Initial evidence suggests that workshop leaders often overlook central tenets of education research that are well established in classroom contexts, such as the role of interactivity in enabling student learning [S. Freeman et al., Proc. Natl. Acad. Sci. U.S.A. 111, 8410 (2014)]. As such, there is a need to develop more robust, evidence-based models of how best to support faculty learning in professional development contexts, and to actively support workshop leaders in relating their design decisions to familiar ideas from other educational contexts. In response to these needs, we have developed an observation tool, the real-time professional development observation tool (R-PDOT), to document the form and focus of faculty engagement during workshops. In this paper, we describe the motivation and methodological considerations behind the development of the R-PDOT, justify our decisions to highlight particular aspects of workshop sessions, and demonstrate how the R-PDOT can be used to analyze three sessions from the Physics and Astronomy New Faculty Workshop. We also justify the accessibility and potential utility of the R-PDOT output as a reflective tool using preliminary data from interviews with workshop leaders, and consider the roles the R-PDOT could play in supporting future research on faculty professional development.

  18. Comparative analysis of dynamic cell viability, migration and invasion assessments by novel real-time technology and classic endpoint assays.

    Directory of Open Access Journals (Sweden)

    Ridha Limame

    Full Text Available BACKGROUND: Cell viability and motility comprise ubiquitous mechanisms involved in a variety of (pathobiological processes including cancer. We report a technical comparative analysis of the novel impedance-based xCELLigence Real-Time Cell Analysis detection platform, with conventional label-based endpoint methods, hereby indicating performance characteristics and correlating dynamic observations of cell proliferation, cytotoxicity, migration and invasion on cancer cells in highly standardized experimental conditions. METHODOLOGY/PRINCIPAL FINDINGS: Dynamic high-resolution assessments of proliferation, cytotoxicity and migration were performed using xCELLigence technology on the MDA-MB-231 (breast cancer and A549 (lung cancer cell lines. Proliferation kinetics were compared with the Sulforhodamine B (SRB assay in a series of four cell concentrations, yielding fair to good correlations (Spearman's Rho 0.688 to 0.964. Cytotoxic action by paclitaxel (0-100 nM correlated well with SRB (Rho>0.95 with similar IC(50 values. Reference cell migration experiments were performed using Transwell plates and correlated by pixel area calculation of crystal violet-stained membranes (Rho 0.90 and optical density (OD measurement of extracted dye (Rho>0.95. Invasion was observed on MDA-MB-231 cells alone using Matrigel-coated Transwells as standard reference method and correlated by OD reading for two Matrigel densities (Rho>0.95. Variance component analysis revealed increased variances associated with impedance-based detection of migration and invasion, potentially caused by the sensitive nature of this method. CONCLUSIONS/SIGNIFICANCE: The xCELLigence RTCA technology provides an accurate platform for non-invasive detection of cell viability and motility. The strong correlations with conventional methods imply a similar observation of cell behavior and interchangeability with other systems, illustrated by the highly correlating kinetic invasion profiles on

  19. Menu labeling perception and health behaviors among immigrant and US born minority populations: assessment in two Los Angeles public markets.

    Science.gov (United States)

    Vargas-Bustamante, Arturo

    2013-01-01

    To analyze menu labeling perception and food choices/health behaviors in two Los Angeles public markets. Labels with food caloric content were displayed in the food court of one of these markets. Bivarate means analyses compared the surveyed population by market and by nativity status. The main predictors of menu-labeling influence were identified in the sample from the market that displayed labels. A separate analysis investigated food choices/health behaviors among immigrant cohorts by time of US residence. Reading labels when shopping was one of the main predictors associated with menu labeling influence. Longer-stayed immigrants were more likely to afford "balanced meals", but they were also more likely to eat in fast food restaurants and less likely to engage into moderate/intense physical activity. While nativity was not a significant predictor of menu labeling influence on food choices, our findings suggest food choices/behaviors convergence among immigrant and US-born populations.

  20. Assessment of resident operative performance using a real-time mobile Web system: preparing for the milestone age.

    Science.gov (United States)

    Wagner, Justin P; Chen, David C; Donahue, Timothy R; Quach, Chi; Hines, O Joe; Hiatt, Jonathan R; Tillou, Areti

    2014-01-01

    : 0.55-1.38) than with CERP measures (mean = 0.37, CI: 0.34-0.41). Additionally, there were consistent increases in each of the OPRS subcategories. In contrast to CERPs, the OPRS fully satisfies the Accreditation Council for Graduate Medical Education and American Board of Surgery operative assessment requirements. The mobile Web platform provides a convenient interface, broad accessibility, automatic data compilation, and compatibility with common database and statistical software. Our mobile OPRS system encourages candid feedback dialog and generates a comprehensive review of individual and group-wide operative proficiency in real time. Copyright © 2014 Association of Program Directors in Surgery. Published by Elsevier Inc. All rights reserved.

  1. Dificultades en los métodos de estudio de exposiciones ambientales y defectos del tubo neural Methodological challenges to assess environmental exposures related to neural tube defects

    Directory of Open Access Journals (Sweden)

    Víctor Hugo Borja-Aburto

    1999-11-01

    Full Text Available Objetivo. Discutir las actitudes en la evaluación de las exposiciones ambientales como factores de riesgo para defectos de riesgo del tubo neural, al tiempo que se presentan los principales factores estudiados hasta la fecha. Resultados. Las exposiciones ambientales se citan muy a menudo como causa de malformaciones congénitas; sin embargo, ha sido difícil establecer esta asociación en los estudios de poblaciones humanas, debido a problemas en su diseño y conducción. Lo anterior es particularmente marcado en el caso del estudio de los defectos del cierre del tubo neural (DTN, que es una de las principales malformaciones y que incluye anencefalia, espina bífida y encefalocele, y su asociación con exposiciones ambientales. Las dificultades en los métodos surgen de: a la medida de frecuencia para realizar comparaciones espacio-temporales; b la clasificación y heterogeneidad de las malformaciones; c la consideración de los factores relacionados con la madre, el padre y el producto, de manera conjunta, y d la evaluación de las exposiciones ambientales. Conclusiones. Hipotéticamente las exposiciones ambientales tanto del padre como de la madre pueden producir daño genético antes y/o después de la concepción por la acción directa sobre el embrión o sobre el complejo fetoplacentario, de tal manera que en la evaluación de exposiciones ambientales: a deben tomarse en cuenta las exposiciones maternas y paternas; b debe considerarse el periodo crítico de exposición, esto es, tres meses anteriores a la concepción para el padre y un mes alrededor de la concepción para la madre; c en la medida de lo posible, la evaluación de la exposición deberá ser cuantitativa, evitando clasificar a los grupos únicamente como expuestos y no expuestos, y d es recomendable emplear marcadores biológicos de exposición siempre que sea posible, así como utilizar marcadores biológicos que permitan clasificar a la población en grupos con distinta

  2. SW-platform for R&D in Applications of Synchrophasor Measurements for Wide-Area Assessment, Control and Visualization in Real-Time

    DEFF Research Database (Denmark)

    Jóhannsson, Hjörtur; Morais, Hugo; Pedersen, Allan Henning Birger

    2014-01-01

    The Danish research project “Secure Operation of Sustainable Power Systems (SOSPO)” is currently being conducted in a collaboration by a group of partners from academia and industry. The focus of the project is on how to achieve secure operation of the power grid as large scale thermal power plants......, supplied by fossil fuel, are phased out in favor of non - controllable renewable energy sources like wind and solar energy. In particular, the SOSPO project aims to develop real - time stability and security assessment methods as well as wide - area control methods to re - establish stable and secure...... realistic conditions, the future system scenarios are represented in a real time grid simulator that is an integrated part of the platform. The SW - platform provides structured access to any model parameter as well as access to real - time phasor measurement unit (PMU) and remote terminal unit (RTU...

  3. Scale for assessing the quality of Mexican adults' mealtime habits Escala para evaluar la calidad de los hábitos al comer en adultos mexicanos

    Directory of Open Access Journals (Sweden)

    Darina Dosamantes-Carrasco

    2011-04-01

    Full Text Available OBJECTIVE: To construct a scale for assessing the quality of mealtime habits in a sample of urban Mexican adults, computing the contribution of a set of advisable and unadvisable mealtime habits. MATERIAL AND METHODS: We performed an exploratory factor analysis among 7 472 adults participating in the baseline assessment of the Health Workers Cohort Study, to assess the mealtime habits quality. Likelihood ratio test for difference of two probabilities and test for the difference of two means were used to identify differences between low and high categories of the Mealtime Habits Quality Scale (MHQS across variables of interest. RESULTS: Participants with the top quality of mealtime habits showed lower rates of overweight, obesity, abdominal obesity, and elevated body fat. They were also more adherent to a prudent dietary pattern than a western dietary pattern, and consumed more fruits and vegetables. CONCLUSIONS: Anthropometric and dietary variables differed across MHQS categories. However, further validation of the scale, and assessment of their ability to predict weight gain or related diseases are needed, using prospective and intervention studies.OBJETIVO: Construir una escala para evaluar la calidad de los hábitos al comer, calculando la contribución de un grupo de hábitos recomendables y no recomendables, en población adulta urbana de México. MATERIAL Y MÉTODOS: Realizamos un análisis exploratorio de factores en 7 472 adultos participantes en el Estudio de Cohorte de Trabajadores de la Salud para evaluar la calidad de los hábitos al comer. Para identificar diferencias entre la baja y alta calidad de los hábitos al comer a través de las variables de interés, utilizamos la prueba de razón de probabilidades a fin de evaluar la diferencia entre dos proporciones y la prueba de comparación de medias. RESULTADOS: Los participantes clasificados en la categoría de alta calidad de los hábitos al comer presentaron prevalencias m

  4. Real-time three-dimensional transesophageal echocardiography in the assessment of mechanical prosthetic mitral valve ring thrombosis.

    Science.gov (United States)

    Ozkan, Mehmet; Gürsoy, Ozan Mustafa; Astarcıoğlu, Mehmet Ali; Gündüz, Sabahattin; Cakal, Beytullah; Karakoyun, Süleyman; Kalçık, Macit; Kahveci, Gökhan; Duran, Nilüfer Ekşi; Yıldız, Mustafa; Cevik, Cihan

    2013-10-01

    Although 2-dimensional (2D) transesophageal echocardiography (TEE) is the gold standard for the diagnosis of prosthetic valve thrombosis, nonobstructive clots located on mitral valve rings can be missed. Real-time 3-dimensional (3D) TEE has incremental value in the visualization of mitral prosthesis. The aim of this study was to investigate the utility of real-time 3D TEE in the diagnosis of mitral prosthetic ring thrombosis. The clinical outcomes of these patients in relation to real-time 3D transesophageal echocardiographic findings were analyzed. Of 1,263 patients who underwent echocardiographic studies, 174 patients (37 men, 137 women) with mitral ring thrombosis detected by real-time 3D TEE constituted the main study population. Patients were followed prospectively on oral anticoagulation for 25 ± 7 months. Eighty-nine patients (51%) had thrombi that were missed on 2D TEE and depicted only on real-time 3D TEE. The remaining cases were partially visualized with 2D TEE but completely visualized with real-time 3D TEE. Thirty-seven patients (21%) had thromboembolism. The mean thickness of the ring thrombosis in patients with thromboembolism was greater than that in patients without thromboembolism (3.8 ± 0.9 vs 2.8 ± 0.7 mm, p 3D TEE during follow-up. There were no thrombi in 39 patients (25%); 45 (29%) had regression of thrombi, and there was no change in thrombus size in 68 patients (44%). Thrombus size increased in 3 patients (2%). Thrombosis was confirmed surgically and histopathologically in 12 patients (7%). In conclusion, real-time 3D TEE can detect prosthetic mitral ring thrombosis that could be missed on 2D TEE and cause thromboembolic events. Copyright © 2013 Elsevier Inc. All rights reserved.

  5. Performance of real-time strain elastography, transient elastography, and aspartate-to-platelet ratio index in the assessment of fibrosis in chronic hepatitis C.

    Science.gov (United States)

    Ferraioli, Giovanna; Tinelli, Carmine; Malfitano, Antonello; Dal Bello, Barbara; Filice, Gaetano; Filice, Carlo; Above, Elisabetta; Barbarini, Giorgio; Brunetti, Enrico; Calderon, Willy; Di Gregorio, Marta; Lissandrin, Raffaella; Ludovisi, Serena; Maiocchi, Laura; Michelone, Giuseppe; Mondelli, Mario; Patruno, Savino F A; Perretti, Alessandro; Poma, Gianluigi; Sacchi, Paolo; Zaramella, Marco; Zicchetti, Mabel

    2012-07-01

    The purpose of this article is to evaluate the diagnostic performance of transient elastography, real-time strain elastography, and aspartate-to-platelet ratio index in assessing fibrosis in patients with chronic hepatitis C by using histologic Metavir scores as reference standard. Consecutive patients with chronic hepatitis C scheduled for liver biopsy were enrolled. Liver biopsy was performed on the same day as transient elastography and real-time strain elastography. Transient elastography and real-time strain elastography were performed in the same patient encounter by a single investigator using a medical device based on elastometry and an ultrasound machine, respectively. Diagnostic performance was assessed by using receiver operating characteristic curves and area under the receiver operating characteristic curve (AUC) analysis. One hundred thirty patients (91 men and 39 women) were analyzed. The cutoff values for transient elastography, real-time strain elastography, and aspartate-to-platelet ratio index were 6.9 kPa, 1.82, and 0.37, respectively, for fibrosis score of 2 or higher; 7.3 kPa, 1.86, and 0.70, respectively, for fibrosis score of 3 or higher; and 9.3 kPa, 2.33, and 0.70, respectively, for fibrosis score of 4. AUC values of transient elastography, real-time strain elastography, aspartate-to-platelet ratio index were 0.88, 0.74, and 0.86, respectively, for fibrosis score of 2 or higher; 0.95, 0.80, and 0.89, respectively, for fibrosis score of 3 or higher; and 0.97, 0.80, and 0.84, respectively, for fibrosis score of 4. A combination of the three methods, when two of three were in agreement, showed AUC curves of 0.93, 0.95, and 0.95 for fibrosis scores of 2 or higher, 3 or higher, and 4, respectively. Transient elastography, real-time strain elastography, and aspartate-to-platelet ratio index values were correlated with histologic stages of fibrosis. Transient elastography offered excellent diagnostic performance in assessing severe fibrosis and

  6. Estereotipos hacia los ancianos

    Directory of Open Access Journals (Sweden)

    Marta Gil Barreiro

    1997-02-01

    Full Text Available Se realizó un estudio descriptivo en 4 grupos etáreos diferentes: 20; 40; 60 y 70 años, del área de salud que abarca el Policlínico Docente "Lawton", con vistas a determinar cómo se estructuran los estereotipos hacia los ancianos. El instrumento de evaluación utilizado se confeccionó para la ocasión: la escala de adjetivos. El estereotipo más positivo hacia los ancianos lo evidenciaron los individuos de 40 años, a los que le siguieron, en orden decreciente, los de 70; 20 y 60 años.A descriptive study was a carried out in four different age groups: 20, 40, 60, and 70 years old, in the health area belonging to the "Lawton" Teaching Policlinic, in order to determine how the stereotypes towards the older people are formulated. The adjective scale was the assessing instrument built for the ocassion. The most positive stereotype towards the elder was demonstrated by individuals 40 years of age, followed in decreasing order, by the 70, 20, and 60 years old groups.

  7. Diagnostic value of real-time elastography in the assessment of hepatic fibrosis in patients with liver iron overload

    International Nuclear Information System (INIS)

    Paparo, Francesco; Cevasco, Luca; Zefiro, Daniele; Biscaldi, Ennio; Bacigalupo, Lorenzo; Balocco, Manuela; Pongiglione, Marta; Banderali, Simone; Forni, Gian Luca; Rollandi, Gian Andrea

    2013-01-01

    Objective: The objective of our prospective monocentric work was to determine the diagnostic value of real-time elastography (RTE) in the assessment of liver fibrosis in patients with iron overload, using transient elastography (TE) as reference standard. Methods: Sixty-seven consecutive patients with MRI detectable iron overload (T2* < 6.3 ms) were enrolled. TE and RTE were performed on the same day as MRI. Elastograms were acquired by an experienced operator and analyzed by calculating the elastic ratio between perihepatic soft tissues and liver parenchyma. An elliptical ROI of 1 cm 2 (Z 1 ) was positioned in the liver parenchyma and a smaller elliptical ROI of 2 mm 2 (Z 2 ) was positioned in a homogeneously soft (red) region of the diaphragm, which was considered as internal control to calculate the elastic ratio Z 2 /Z 1 . Results: Seven patients were excluded because of invalid TE or RTE examinations. The remaining 60 patients were 57% males and 43% females (mean age: 42 [21–76] years), including 37 homozygous-β-thalassemics, 13 patients with β-thalassemia intermedia, 6 with primary hemochromatosis, and 4 with myelodysplastic syndrome. Increasing elastic ratios were significantly correlated with increasing TE values (r = 0.645, 95% CI 0.468–0.772, P < 0.0001). The mean elastic ratios for each METAVIR group were as follows: F0/1 = 1.9 ± 0.4; F2 = 2.2 ± 0.4; F3 = 2.9 ± 0.5; F4 = 3.2 ± 0.4. The diagnostic accuracy of RTE for F ≥ 2 evaluated by AUC-ROC analysis was 0.798 (95% CI 0.674–0.890). The diagnostic accuracy of RTE for F ≥ 3 was 0.909 (95% CI 0.806–0.968). At a cut-off ≥ 2.75, RTE showed a sensitivity of 70% (95% CI 45.7–88.1) and a specificity of 97.5% (95% CI 86.8–99.9). Conclusions: In patients with MRI-detectable liver iron-overload RTE allows to discriminate between F0/1–F2 and F3–F4 with a reasonable diagnostic accuracy

  8. Diagnostic value of real-time elastography in the assessment of hepatic fibrosis in patients with liver iron overload

    Energy Technology Data Exchange (ETDEWEB)

    Paparo, Francesco [Department of Radiology, E.O. Ospedali Galliera, Mura della Cappuccine 14, 16128 Genoa (Italy); Cevasco, Luca [School of Radiology, University of Genoa, Via Leon Battista Alberti 4, 16132 Genoa (Italy); Zefiro, Daniele [Medical Physics Department, E.O. Ospedali Galliera, Mura della Cappuccine 14, 16128 Genoa (Italy); Biscaldi, Ennio; Bacigalupo, Lorenzo [Department of Radiology, E.O. Ospedali Galliera, Mura della Cappuccine 14, 16128 Genoa (Italy); Balocco, Manuela [Unit of Microcitemia and Hereditary Anaemias, E.O. Ospedali Galliera, Mura della Cappuccine 14, 16128 Genoa (Italy); Pongiglione, Marta; Banderali, Simone [Department of Radiology, E.O. Ospedali Galliera, Mura della Cappuccine 14, 16128 Genoa (Italy); Forni, Gian Luca [Unit of Microcitemia and Hereditary Anaemias, E.O. Ospedali Galliera, Mura della Cappuccine 14, 16128 Genoa (Italy); Rollandi, Gian Andrea, E-mail: gian.andrea.rollandi@galliera.it [Department of Radiology, E.O. Ospedali Galliera, Mura della Cappuccine 14, 16128 Genoa (Italy)

    2013-12-01

    Objective: The objective of our prospective monocentric work was to determine the diagnostic value of real-time elastography (RTE) in the assessment of liver fibrosis in patients with iron overload, using transient elastography (TE) as reference standard. Methods: Sixty-seven consecutive patients with MRI detectable iron overload (T2* < 6.3 ms) were enrolled. TE and RTE were performed on the same day as MRI. Elastograms were acquired by an experienced operator and analyzed by calculating the elastic ratio between perihepatic soft tissues and liver parenchyma. An elliptical ROI of 1 cm{sup 2} (Z{sub 1}) was positioned in the liver parenchyma and a smaller elliptical ROI of 2 mm{sup 2} (Z{sub 2}) was positioned in a homogeneously soft (red) region of the diaphragm, which was considered as internal control to calculate the elastic ratio Z{sub 2}/Z{sub 1}. Results: Seven patients were excluded because of invalid TE or RTE examinations. The remaining 60 patients were 57% males and 43% females (mean age: 42 [21–76] years), including 37 homozygous-β-thalassemics, 13 patients with β-thalassemia intermedia, 6 with primary hemochromatosis, and 4 with myelodysplastic syndrome. Increasing elastic ratios were significantly correlated with increasing TE values (r = 0.645, 95% CI 0.468–0.772, P < 0.0001). The mean elastic ratios for each METAVIR group were as follows: F0/1 = 1.9 ± 0.4; F2 = 2.2 ± 0.4; F3 = 2.9 ± 0.5; F4 = 3.2 ± 0.4. The diagnostic accuracy of RTE for F ≥ 2 evaluated by AUC-ROC analysis was 0.798 (95% CI 0.674–0.890). The diagnostic accuracy of RTE for F ≥ 3 was 0.909 (95% CI 0.806–0.968). At a cut-off ≥ 2.75, RTE showed a sensitivity of 70% (95% CI 45.7–88.1) and a specificity of 97.5% (95% CI 86.8–99.9). Conclusions: In patients with MRI-detectable liver iron-overload RTE allows to discriminate between F0/1–F2 and F3–F4 with a reasonable diagnostic accuracy.

  9. Towards a real-time susceptibility assessment of rainfall-induced shallow landslides on a regional scale

    Directory of Open Access Journals (Sweden)

    L. Montrasio

    2011-07-01

    Full Text Available In the framework of landslide risk management, it appears relevant to assess, both in space and in time, the triggering of rainfall-induced shallow landslides, in order to prevent damages due to these kind of disasters. In this context, the use of real-time landslide early warning systems has been attracting more and more attention from the scientific community. This paper deals with the application, on a regional scale, of two physically-based stability models: SLIP (Shallow Landslides Instability Prediction and TRIGRS (Transient Rainfall Infiltration and Grid-based Regional Slope-stability analysis. A back analysis of some recent case-histories of soil slips which occurred in the territory of the central Emilian Apennine, Emilia Romagna Region (Northern Italy is carried out and the main results are shown. The study area is described from geological and climatic viewpoints. The acquisition of geospatial information regarding the topography, the soil properties and the local landslide inventory is also explained.

    The paper outlines the main features of the SLIP model and the basic assumptions of TRIGRS. Particular attention is devoted to the discussion of the input data, which have been stored and managed through a Geographic Information System (GIS platform. Results of the SLIP model on a regional scale, over a one year time interval, are finally presented. The results predicted by the SLIP model are analysed both in terms of safety factor (Fs maps, corresponding to particular rainfall events, and in terms of time-varying percentage of unstable areas over the considered time interval. The paper compares observed landslide localizations with those predicted by the SLIP model. A further quantitative comparison between SLIP and TRIGRS, both applied to the most important event occurred during the analysed period, is presented. The limits of the SLIP model, mainly due to some restrictions of simplifying the physically

  10. Aplicación de los microcontroladores a la docencia de sistemas digitales: “Termómetro digital a tiempo real y conexión serie a PC”

    OpenAIRE

    Ramírez Mendoza, Agurtzane

    2006-01-01

    El objetivo de este Trabajo de Fin de Carrera es servir de referencia para una práctica de la asignatura de Sistemas Electrónicos Digitales. Se diseñará el hardware y el software necesario para que, paso a paso, los alumnos de esta asignatura entren en contacto con el mundo de los microcontrolador, y más concretamente con el PIC16F87XA. Mediante pasos sencillos el alumno tomará contacto con los periféricos más importantes de este microcontrolador, formándose una base consist...

  11. Response of a diuron-degrading community to diuron exposure assessed by real-time quantitative PCR monitoring of phenylurea hydrolase A and B encoding genes

    OpenAIRE

    Pesce , S.; Beguet , J.; Rouard , N.; Devers Lamrani , M.; Martin Laurent , F.

    2013-01-01

    A real-time quantitative PCR method was developed to detect and quantify phenlylurea hydrolase genes' (puhA and puhB) sequences from environmental DNA samples to assess diuron-degrading genetic potential in some soil and sediment microbial communities. In the soil communities, mineralization rates (determined with [ring-14C]-labeled diuron) were linked to diuron-degrading genetic potentials estimated from puhB number copies, which increased following repeated diuron treatments. In the sedimen...

  12. Incremental value of live/real time three-dimensional transesophageal echocardiography over the two-dimensional technique in the assessment of primary cardiac malignant fibrous histiocytoma.

    Science.gov (United States)

    Gok, Gulay; Elsayed, Mahmoud; Thind, Munveer; Uygur, Begum; Abtahi, Firoozeh; Chahwala, Jugal R; Yıldırımtürk, Özlem; Kayacıoğlu, İlyas; Pehlivanoğlu, Seçkin; Nanda, Navin C

    2015-07-01

    We describe a case of primary cardiac malignant fibrous histiocytoma where live/real time three-dimensional transesophageal echocardiography added incremental value to the two-dimensional modalities. Specifically, the three-dimensional technique allowed us to delineate the true extent and infiltration of the tumor, to identify characteristics of the tumor mass suggestive of its malignant nature, and to quantitatively assess the total tumor burden. © 2015, Wiley Periodicals, Inc.

  13. Use of the exposure unit concept in risk assessments: A case study for Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Hartmann, H.M.; Butler, J.P.; Dorries, A.M.; Beck, J.R.

    1993-10-01

    The use of the exposure unit concept to refine intake estimates in quantitative risk assessments is explained. The selection of appropriate exposure unit areas for varying receptors and the application of the concept to large sites and to relatively small solid waste management units (SWMUs) are discussed. Examples are presented

  14. Assessing the real-world cost-effectiveness of adjuvant trastuzumab in HER-2/neu positive breast cancer.

    LENUS (Irish Health Repository)

    Hedden, Lindsay

    2012-01-01

    Among women with surgically removed, high-risk HER-2\\/neu-positive breast cancer, trastuzumab has demonstrated significant improvements in disease-free and overall survival. The objective of this study is to evaluate the cost-effectiveness of the currently recommended 12-month adjuvant protocol of trastuzumab using a Markov modeling approach and real-world cost data.

  15. Quantitative and qualitative assessment of real world data comparative effectiveness research of systemic therapies in lung oncology: A systematic review

    NARCIS (Netherlands)

    Peters, Bas J.M.; Janssen, Vivi E.M.T.; Schramel, Franz M.; van de Garde, Ewoudt M.W.

    2016-01-01

    Introduction The growing interest in comparative effectiveness research (CER) based on data from routine clinical practice also extends towards lung oncology. Although CER studies using real world data (RWD) have the potential to assist clinical decision-making, concerns about the quality and

  16. Simultaneous quantitative assessment of circulating cell-free mitochondrial and nuclear DNA by multiplex real-time PCR

    Directory of Open Access Journals (Sweden)

    Peng Xia

    2009-01-01

    Full Text Available Quantification of circulating nucleic acids in plasma and serum could be used as a non-invasive diagnostic tool for monitoring a wide variety of diseases and conditions. We describe here a rapid, simple and accurate multiplex real-time PCR method for direct synchronized analysis of circulating cell-free (ccf mitochondrial (mtDNA and nuclear (nDNA DNA in plasma and serum samples. The method is based on one-step multiplex real-time PCR using a FAM-labeled MGB probe and primers to amplify the mtDNA sequence of the ATP 8 gene, and a VIC-labeled MGB probe and primers to amplify the nDNA sequence of the glycerinaldehyde-3-phosphate-dehydrogenase (GAPDH gene, in plasma and serum samples simultaneously. The efficiencies of the multiplex assays were measured in serial dilutions. Based on the simulation of the PCR reaction kinetics, the relative quantities of ccf mtDNA were calculated using a very simple equation. Using our optimised real-time PCR conditions, close to 100% efficiency was obtained from the two assays. The two assays performed in the dilution series showed very good and reproducible correlation to each other. This optimised multiplex real-time PCR protocol can be widely used for synchronized quantification of mtDNA and nDNA in different samples, with a very high rate of efficiency.

  17. Function Modelling Of The Market And Assessing The Degree Of Similarity Between Real Properties - Dependent Or Independent Procedures In The Process Of Office Property Valuation

    Directory of Open Access Journals (Sweden)

    Barańska Anna

    2015-09-01

    Full Text Available Referring to the developed and presented in previous publications (e.g. Barańska 2011 two-stage algorithm for real estate valuation, this article addresses the problem of the relationship between the two stages of the algorithm. An essential part of the first stage is the multi-dimensional function modelling of the real estate market. As a result of selecting the model best fitted to the market data, in which the dependent variable is always the price of a real property, a set of market attributes is obtained, which in this model are considered to be price-determining. In the second stage, from the collection of real estate which served as a database in the process of estimating model parameters, the selected objects are those which are most similar to the one subject to valuation and form the basis for predicting the final value of the property being valued. Assessing the degree of similarity between real properties can be carried out based on the full spectrum of real estate attributes that potentially affect their value and which it is possible to gather information about, or only on the basis of those attributes which were considered to be price-determining in function modelling. It can also be performed by various methods. This article has examined the effect of various approaches on the final value of the property obtained using the two-stage prediction. In order fulfill the study aim precisely as possible, the results of each calculation step of the algorithm have been investigated in detail. Each of them points to the independence of the two procedures.

  18. LA EDUCACIÓN SEXUAL DEL COLECTIVO TRANS: UNA COMPARACIÓN ENTRE EL CURRÍCULO REAL DE UN BACHILLERATO POPULAR Y EL PRESCRIPTO EN LOS LINEAMIENTOS CURRICULARES NACIONALES DE ARGENTINA

    Directory of Open Access Journals (Sweden)

    Eugenia Grotz

    2016-10-01

    educación en los materiales difundidos por el Ministerio de Educación de la Nación, generamos 6 categorías para el análisis de los contenidos de ESI propuestos en los LCN para el Área de Ciencias Naturales y Educación para la Salud, y luego comparamos estos contenidos con la información obtenida de una entrevista con el docente de Educación para la Salud en el Bachillerato trans. Así, pudimos identificar contenidos sobre ESI que se trabajan con una perspectiva distinta de la que plantean los LCN y contenidos que directamente están ausentes en dichos lineamientos, y cuya incorporación consideramos conveniente tanto para la educación del colectivo trans como para la sociedad en su conjunto.

  19. Economic assessment of R and D with real options in the field of fast reactors taking into account uncertainty on their competitiveness: the case of France

    International Nuclear Information System (INIS)

    Taverdet-Popiolek, Nathalie; Shoai Tehrani, Bianka

    2013-01-01

    In a context of potential worldwide nuclear development, this paper aims at assessing the economic value of pursuing research in Generation IV fast reactors today, given that it would allow industrial deployment around 2040 in case of high uranium prices. Two key variables shall be considered as inputs for the assessment: the price of uranium and the over-cost of Generation IV reactors compared to the previous generation. Our model based on real options theory demonstrates that this value is positive and outweighs the risks associated with the competitiveness of Generation IV. (authors)

  20. Implementation of a Flexible Bayesian Classifier for the Assessment of Patient’s Activities within a Real-time Personalized Mobile Application

    Directory of Open Access Journals (Sweden)

    V. Miskovic

    2017-02-01

    Full Text Available This paper presents an implementation of a mobile application that provides a real-time personalized assessment of patient’s activities by using a Flexible Bayesian Classifier. The personalized assessment is derived from data collected from the 3-axial accelerometer sensor and the counting steps sensor, both widespread among nowadays mobile devices. Despite the fact that online mobile solutions with Bayesian Classifier have been rare and insufficiently precise, we have proven that the accuracy of the proposed system within a defined data model is comparable to the accuracy of decision trees and neural networks.

  1. Does a 20-week aerobic exercise training programme increase our capabilities to buffer real-life stressors? A randomized, controlled trial using ambulatory assessment.

    Science.gov (United States)

    von Haaren, Birte; Ottenbacher, Joerg; Muenz, Julia; Neumann, Rainer; Boes, Klaus; Ebner-Priemer, Ulrich

    2016-02-01

    The cross-stressor adaptation hypothesis suggests that regular exercise leads to adaptations in the stress response systems that induce decreased physiological responses to psychological stressors. Even though an exercise intervention to buffer the detrimental effects of psychological stressors on health might be of utmost importance, empirical evidence is mixed. This may be explained by the use of cross-sectional designs and non-personally relevant stressors. Using a randomized controlled trial, we hypothesized that a 20-week aerobic exercise training does reduce physiological stress responses to psychological real-life stressors in sedentary students. Sixty-one students were randomized to either a control group or an exercise training group. The academic examination period (end of the semester) served as a real-life stressor. We used ambulatory assessment methods to assess physiological stress reactivity of the autonomic nervous system (heart rate variability: LF/HF, RMSSD), physical activity and perceived stress during 2 days of everyday life and multilevel models for data analyses. Aerobic capacity (VO2max) was assessed pre- and post-intervention via cardiopulmonary exercise testing to analyze the effectiveness of the intervention. During real-life stressors, the exercise training group showed significantly reduced LF/HF (β = -0.15, t = -2.59, p = .01) and increased RMSSD (β = 0.15, t = 2.34, p = .02) compared to the control group. Using a randomized controlled trial and a real-life stressor, we could show that exercise appears to be a useful preventive strategy to buffer the effects of stress on the autonomic nervous system, which might result into detrimental health outcomes.

  2. Assessment of SCAR markers to design real-time PCR primers for rhizosphere quantification of Azospirillum brasilense phytostimulatory inoculants of maize.

    Science.gov (United States)

    Couillerot, O; Poirier, M-A; Prigent-Combaret, C; Mavingui, P; Caballero-Mellado, J; Moënne-Loccoz, Y

    2010-08-01

    To assess the applicability of sequence characterized amplified region (SCAR) markers obtained from BOX, ERIC and RAPD fragments to design primers for real-time PCR quantification of the phytostimulatory maize inoculants Azospirillum brasilense UAP-154 and CFN-535 in the rhizosphere. Primers were designed based on strain-specific SCAR markers and were screened for successful amplification of target strain and absence of cross-reaction with other Azospirillum strains. The specificity of primers thus selected was verified under real-time PCR conditions using genomic DNA from strain collection and DNA from rhizosphere samples. The detection limit was 60 fg DNA with pure cultures and 4 x 10(3) (for UAP-154) and 4 x 10(4) CFU g(-1) (for CFN-535) in the maize rhizosphere. Inoculant quantification was effective from 10(4) to 10(8) CFU g(-1) soil. BOX-based SCAR markers were useful to find primers for strain-specific real-time PCR quantification of each A. brasilense inoculant in the maize rhizosphere. Effective root colonization is a prerequisite for successful Azospirillum phytostimulation, but cultivation-independent monitoring methods were lacking. The real-time PCR methods developed here will help understand the effect of environmental conditions on root colonization and phytostimulation by A. brasilense UAP-154 and CFN-535.

  3. The Los Alamos primer

    CERN Document Server

    Serber, Robert

    2018-01-01

    Unabridged declassified value reproduction of The Los Alamos Primer by Robert Serber, in full color with all censor markings. This is the booklet given to new workers at Los Alamos during World War II, to catch them up on how to build a practical fission bomb. The Primer was driven by Robert Oppenheimer asking his protégé Robert Serber to summarize all knowledge and possible solutions known as of April 1943 in a series of lectures. Serber did such an excellent job that the notes from the series was turned into The Los Alamos Primer. Serber was known as an expert that bridged theory and reality, and so was also chosen to be one of the first Americans to enter Hiroshima and Nagasaki to assess the atomic damage in 1945.

  4. Risk assessment of the retrieval of transuranic waste: Pads 1, 2, and 4, Technical Area-54, Area G Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Wilbert, K.A.; Lyon, B.F.; Hutchison, J.; Holmes, J.A.; Legg, J.L.; Simek, M.P.; Travis, C.C.; Wollert, D.A.

    1995-05-01

    The Risk Assessment for the Retrieval of Transuranic Waste is a comparative risk assessment of the potential adverse human health effects resulting from exposure to contaminants during retrieval and post-retrieval aboveground storage operations of post-1970 earthen-covered transuranic waste. Two alternatives are compared: (1) Immediate Retrieval and (2) Delayed Retrieval. Under the Immediate Retrieval Alternative, retrieval of the waste is assumed to begin immediately, Under the Delayed Retrieval Alternative, retrieval is delayed 10 years. The current risk assessment is on Pads 1, 2, and 4, at Technical Area-54, Area-G, Los Alamos National Laboratory (LANL). Risks are assessed independently for three scenarios: (1) incident-free retrieval operations, (2) incident-free storage operations, and (3) a drum failure analysis. The drum failure analysis evaluates container integrity under both alternatives and assesses the impacts of potential drum failures during retrieval operations. Risks associated with a series of drum failures are potentially severe for workers, off-site receptors, and general on-site employees if retrieval is delayed 10 years and administrative and engineering controls remain constant. Under the Delayed Retrieval Alternative, an average of 300 drums out of 16,647 are estimated to fail during retrieval operations due to general corrosion, while minimal drums are predicted to fail under the Immediate Retrieval Alternative. The results of the current study suggest that, based on risk, remediation of Pads 1, 2, and 4 at LANL should not be delayed. Although risks from incident-free operations in the Delayed Retrieval Alternative are low, risks due to corrosion and drum failures are potentially severe

  5. The Toxic Exposure Surveillance System (TESS): Risk assessment and real-time toxicovigilance across United States poison centers

    International Nuclear Information System (INIS)

    Watson, William A.; Litovitz, Toby L.; Belson, Martin G.; Funk Wolkin, Amy B.; Patel, Manish; Schier, Joshua G.; Reid, Nicole E.; Kilbourne, Edwin; Rubin, Carol

    2005-01-01

    The Toxic Exposure Surveillance System (TESS) is a uniform data set of US poison centers cases. Categories of information include the patient, the caller, the exposure, the substance(s), clinical toxicity, treatment, and medical outcome. The TESS database was initiated in 1985, and provides a baseline of more than 36.2 million cases through 2003. The database has been utilized for a number of safety evaluations. Consideration of the strengths and limitations of TESS data must be incorporated into data interpretation. Real-time toxicovigilance was initiated in 2003 with continuous uploading of new cases from all poison centers to a central database. Real-time toxicovigilance utilizing general and specific approaches is systematically run against TESS, further increasing the potential utility of poison center experiences as a means of early identification of potential public health threats

  6. The Toxic Exposure Surveillance System (TESS): risk assessment and real-time toxicovigilance across United States poison centers.

    Science.gov (United States)

    Watson, William A; Litovitz, Toby L; Belson, Martin G; Wolkin, Amy B Funk; Patel, Manish; Schier, Joshua G; Reid, Nicole E; Kilbourne, Edwin; Rubin, Carol

    2005-09-01

    The Toxic Exposure Surveillance System (TESS) is a uniform data set of US poison centers cases. Categories of information include the patient, the caller, the exposure, the substance(s), clinical toxicity, treatment, and medical outcome. The TESS database was initiated in 1985, and provides a baseline of more than 36.2 million cases through 2003. The database has been utilized for a number of safety evaluations. Consideration of the strengths and limitations of TESS data must be incorporated into data interpretation. Real-time toxicovigilance was initiated in 2003 with continuous uploading of new cases from all poison centers to a central database. Real-time toxicovigilance utilizing general and specific approaches is systematically run against TESS, further increasing the potential utility of poison center experiences as a means of early identification of potential public health threats.

  7. Los Monjes

    Directory of Open Access Journals (Sweden)

    Nicolás Salom Franco

    2002-01-01

    Full Text Available El título de este estudio debiera causar escalofrío en la concienciacolombiana pues se trata de uno de los episodios de mayor desdoro denuestra vida diplomática e institucional.El 22 de Noviembre se cumplen cincuenta años, - medio siglo – dehaber cursado nuestra Cancillería al gobierno de Venezuela, la «NotaDiplomática» más desafortunada por no darle otro calificativo, quegobierno alguno haya podido concebir renunciando graciosamente,contra toda evidencia histórica y jurídica a nuestra soberanía en unaparte del maritorio nacional, cuya aparente insignificancia sólo tuvo ytiene como sustento, la ignorancia jurídica y mucho de la estrechez dela mentalidad andina y mediterránea que con persistente prolongaciónen el tiempo por su desprecio de nuestro inmenso espacio marítimojurisdiccional, ha dominado y domina al Ministerio de RelacionesExteriores, con escasos intervalos de lúcida excepción. Para que no seborre de la memoria colectiva este baldón, como homenaje póstumo a larecta exégesis jurídica y también como toque de alerta a los nuevosprotagonistas de nuestra descaecida diplomacia - así sea ominoso surecuerdo - volvemos en estas páginas a hacer una reseña histórica de losepisodios que condujeron al auto despojo de nuestra soberanía maríti-ma, al regalársele los islotes y cayos de «Los Monjes» a la «hermana»República de Venezuela

  8. Bayesian Algorithm Implementation in a Real Time Exposure Assessment Model on Benzene with Calculation of Associated Cancer Risks

    OpenAIRE

    Sarigiannis, Dimosthenis A.; Karakitsios, Spyros P.; Gotti, Alberto; Papaloukas, Costas L.; Kassomenos, Pavlos A.; Pilidis, Georgios A.

    2009-01-01

    The objective of the current study was the development of a reliable modeling platform to calculate in real time the personal exposure and the associated health risk for filling station employees evaluating current environmental parameters (traffic, meteorological and amount of fuel traded) determined by the appropriate sensor network. A set of Artificial Neural Networks (ANNs) was developed to predict benzene exposure pattern for the filling station employees. Furthermore, a Physiology Based...

  9. QC-ART: A tool for real-time quality control assessment of mass spectrometry-based proteomics data.

    Science.gov (United States)

    Stanfill, Bryan A; Nakayasu, Ernesto S; Bramer, Lisa M; Thompson, Allison M; Ansong, Charles K; Clauss, Therese; Gritsenko, Marina A; Monroe, Matthew E; Moore, Ronald J; Orton, Daniel J; Piehowski, Paul D; Schepmoes, Athena A; Smith, Richard D; Webb-Robertson, Bobbie-Jo; Metz, Thomas O; TEDDY Study Group, The Environmental Determinants Of Diabetes In The Young

    2018-04-17

    Liquid chromatography-mass spectrometry (LC-MS)-based proteomics studies of large sample cohorts can easily require from months to years to complete. Acquiring consistent, high-quality data in such large-scale studies is challenging because of normal variations in instrumentation performance over time, as well as artifacts introduced by the samples themselves, such as those due to collection, storage and processing. Existing quality control methods for proteomics data primarily focus on post-hoc analysis to remove low-quality data that would degrade downstream statistics; they are not designed to evaluate the data in near real-time, which would allow for interventions as soon as deviations in data quality are detected.  In addition to flagging analyses that demonstrate outlier behavior, evaluating how the data structure changes over time can aide in understanding typical instrument performance or identify issues such as a degradation in data quality due to the need for instrument cleaning and/or re-calibration.  To address this gap for proteomics, we developed Quality Control Analysis in Real-Time (QC-ART), a tool for evaluating data as they are acquired in order to dynamically flag potential issues with instrument performance or sample quality.  QC-ART has similar accuracy as standard post-hoc analysis methods with the additional benefit of real-time analysis.  We demonstrate the utility and performance of QC-ART in identifying deviations in data quality due to both instrument and sample issues in near real-time for LC-MS-based plasma proteomics analyses of a sample subset of The Environmental Determinants of Diabetes in the Young cohort. We also present a case where QC-ART facilitated the identification of oxidative modifications, which are often underappreciated in proteomic experiments. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.

  10. Quantification of Fusarium graminearum and Fusarium culmorum by real-time PCR system and zearalenone assessment in maize

    International Nuclear Information System (INIS)

    Atoui, A.; El Khoury, A.; Kallassy, M.; Lebrihi, A.

    2012-01-01

    Zearalenone (ZEA) is a mycotoxin produced by some species of Fusarium, especially by Fusarium grami- nearum and F. culmorum. ZEA induces hyperoestrogenic responses in mammals and can result in reproductive disorders in farm animals. In the present study, a real-time PCR (qPCR) assay has been successfully developed for the detection and quantification of Fusarium graminearum based on primers targeting the gene PKS13 involved in ZEA biosynthesis. A standard curve was developed by plotting the logarithm of known concentrations of F. graminearum DNA against the cycle threshold (Ct) value. The developed real time PCR system was also used to analyze the occurrence of zearalenone producing F. graminearum strains on maize. In this context, DNA extractions were performed from thirty-two maize samples, and subjected to real time PCR. Maize samples also were analyzed for zearalenone content by HPLC. F. graminearum DNA content (pg DNA/ mg of maize) was then plotted against ZEA content (ppb) in maize samples. The regression curve showed a positive and good correlation (R2 = 0.760) allowing for the estimation of the potential risk from ZEA contamination. Consequently, this work offers a quick alternative to conventional methods of ZEA quantification and mycological detection and quantification of F. graminearum in maize. (author)

  11. The Use of OMPS Near Real Time Products in Volcanic Cloud Risk Mitigation and Smoke/Dust Air Quality Assessments

    Science.gov (United States)

    Seftor, C. J.; Krotkov, N. A.; McPeters, R. D.; Li, J. Y.; Durbin, P. B.

    2015-12-01

    Near real time (NRT) SO2 and aerosol index (AI) imagery from Aura's Ozone Monitoring Instrument (OMI) has proven invaluable in mitigating the risk posed to air traffic by SO2 and ash clouds from volcanic eruptions. The OMI products, generated as part of NASA's Land, Atmosphere Near real-time Capability for EOS (LANCE) NRT system and available through LANCE and both NOAA's NESDIS and ESA's Support to Aviation Control Service (SACS) portals, are used to monitor the current location of volcanic clouds and to provide input into Volcanic Ash (VA) advisory forecasts. NRT products have recently been developed using data from the Ozone Mapping and Profiler Suite onboard the Suomi NPP platform; they are currently being made available through the SACS portal and will shortly be incorporated into the LANCE NRT system. We will show examples of the use of OMPS NRT SO2 and AI imagery to monitor recent volcanic eruption events. We will also demonstrate the usefulness of OMPS AI imagery to detect and track dust storms and smoke from fires, and how this information can be used to forecast their impact on air quality in areas far removed from their source. Finally, we will show SO2 and AI imagery generated from our OMPS Direct Broadcast data to highlight the capability of our real time system.

  12. Assessment of Real-Time Compaction Quality Test Indexes for Rockfill Material Based on Roller Vibratory Acceleration Analysis

    Directory of Open Access Journals (Sweden)

    Tianbo Hua

    2018-01-01

    Full Text Available Compaction quality is directly related to the structure and seepage stability of a rockfill dam. To timely and accurately test the compaction quality of the rockfill material, four real-time test indexes were chosen to characterize the soil compaction degree based on the analysis of roller vibratory acceleration, including acceleration peak value (ap, acceleration root mean square value (arms, crest factor value (CF, and compaction meter value (CMV. To determine which of these indexes is the most appropriate, a two-part field compaction experiment was conducted using a vibratory roller in different filling zones of the dam body. Data on rolling parameters, real-time test indexes, and compaction quality indexes were collected to perform statistical regression analyses. Combined with the spectrum analysis of the acceleration signal, it was found that the CF index best characterizes the compaction degree of the rockfill material among the four indexes. Furthermore, the quantitative relations between the real-time index and compaction quality index were established to determine the control criterion of CF, which can instruct the site work of compaction quality control in the rockfill rolling process.

  13. Medical work Assessment in German hospitals: a Real-time Observation study (MAGRO – the study protocol

    Directory of Open Access Journals (Sweden)

    Mache Stefanie

    2009-06-01

    Full Text Available Abstract Background The increasing economic pressure characterizes the current situation in health care and the need to justify medical decisions and organizational processes due to limited financial resources is omnipresent. Physicians tend to interpret this development as a decimation of their own medical influence. This becomes even more obvious after a change in hospital ownership i.e. from a public to a private profit oriented organization. In this case each work procedure is revised. To date, most research studies have focused mainly on differences between hospitals of different ownership regarding financial outcomes and quality of care, leaving important organizational issues unexplored. Little attention has been devoted to the effects of hospital ownership on physicians' working routines. The aim of this observational real time study is to deliver exact data about physicians' work at hospitals of different ownership. Methods The consequences of different management types on the organizational structures of the physicians' work situation and on job satisfaction in the ward situation are monitored by objective real time studies and multi-level psycho diagnostic measurements. Discussion This study is unique in its focus. To date no results have been found for computer-based real time studies on work activity in the clinical field in order to objectively evaluate a physician's work-related stress. After a complete documentation of the physicians' work processes the daily work flow can be estimated and systematically optimized. This can stimulate an overall improvement of health care services in Germany.

  14. Concurrent measurement of "real-world" stress and arousal in individuals with psychosis: assessing the feasibility and validity of a novel methodology.

    Science.gov (United States)

    Kimhy, David; Delespaul, Philippe; Ahn, Hongshik; Cai, Shengnan; Shikhman, Marina; Lieberman, Jeffrey A; Malaspina, Dolores; Sloan, Richard P

    2010-11-01

    Psychosis has been repeatedly suggested to be affected by increases in stress and arousal. However, there is a dearth of evidence supporting the temporal link between stress, arousal, and psychosis during "real-world" functioning. This paucity of evidence may stem from limitations of current research methodologies. Our aim is to the test the feasibility and validity of a novel methodology designed to measure concurrent stress and arousal in individuals with psychosis during "real-world" daily functioning. Twenty patients with psychosis completed a 36-hour ambulatory assessment of stress and arousal. We used experience sampling method with palm computers to assess stress (10 times per day, 10 AM → 10 PM) along with concurrent ambulatory measurement of cardiac autonomic regulation using a Holter monitor. The clocks of the palm computer and Holter monitor were synchronized, allowing the temporal linking of the stress and arousal data. We used power spectral analysis to determine the parasympathetic contributions to autonomic regulation and sympathovagal balance during 5 minutes before and after each experience sample. Patients completed 79% of the experience samples (75% with a valid concurrent arousal data). Momentary increases in stress had inverse correlation with concurrent parasympathetic activity (ρ = -.27, P feasibility and validity of our methodology in individuals with psychosis. The methodology offers a novel way to study in high time resolution the concurrent, "real-world" interactions between stress, arousal, and psychosis. The authors discuss the methodology's potential applications and future research directions.

  15. LOS ALAMOS

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    Following the historic observation of neutrinos in the mid-1950s by two Los Alamos scientists, Fred Reines and Clyde Cowan, Jr, using inverse beta decay, there has been a long and distinguished history of experimental neutrino physics at LAMPF, the Los Alamos Meson Physics Facility. LAMPF is the only meson factory to have had an experimental neutrino programme. In the late 1970s, the first LAMPF neutrino experiment used a 6-tonne water Cherenkov detector 7 metres from the beam stop. A collaboration of Yale, Los Alamos and several other institutions, this experiment searched for the forbidden decay of a muon into an electron and two neutrinos, and measured the reaction rate of a neutrino interacting with a deuteron to give two protons and an electron - the inverse of the reaction that drives the sun's primary energy source. The next LAMPF neutrino experiment, a UC Irvine/Maryland/Los Alamos collaboration, ran from 1982 through 1986 and measured the elastic scattering rate of electron neutrinos and protons, where both neutral and charged weak currents contribute. With its precision of about 15%, the experiment provided the first demonstration of (destructive) interference between the charged and neutral currents. More recent neutrino experiments at LAMPF have searched for neutrino oscillations, especially between muon- and electron-neutrinos. The newest experiment to pursue this physics (as well as oscillations in other channels) is LSND (July/ August, page 10 and cover). In addition to searching for these oscillations, LSND will measure neutrino-proton elastic scattering at low momentum transfer, providing a sensitive measure of the strange quark contribution to the proton spin. LSND began taking data in August. Los Alamos physicists have also been busy in neutrino physics experiments elsewhere. One such experiment looked at the beta decay of free molecular tritium to obtain an essentially model independent determination of the electron-neutrino mass. The

  16. La vida social de los precios: evaluaciones monetarias y acción económica en los mercados de la seguridad privada = The social life of prices: monetary assessments and economic action in private security markets

    Directory of Open Access Journals (Sweden)

    Valcarce, Federico Lorenc

    2010-01-01

    Full Text Available A partir de un estudio sobre los mercados de la seguridad privada en Argentina, el presente artículo aborda la manera en que los precios son producidos, percibidos, interpretados y manipulados en el curso de las acciones económicas de diversos agentes, así como las estrategias se despliegan para controlar la competencia y el intercambio. Mi trabajo se apoya sobre unas treinta entrevistas con dirigentes de empresas de seguridad y unas cuarenta entrevistas con diversos clientes de esas empresas, además de observaciones realizadas en unas veinte empresas del sector e intercambios informales con informantes clave. Además, me sirvo de materiales producidos por organismos públicos, por cámaras y entidades profesionales del ámbito de la seguridad, y por las propias empresas. En el desarrollo del trabajo, muestro que los precios son negociados en el curso de las transacciones mercantiles y que los actores introducen otros principios de interacción que la competencia para tratar de asegurar la rentabilidad de sus empresas o la calidad de los productos que compran

  17. Indicadores para evaluar la salud reproductiva y los programas pertinentes Indicators for assessing reproductive health and programs that address it

    Directory of Open Access Journals (Sweden)

    1998-01-01

    Full Text Available This report presents a set of indicators to aid in the assessment of reproductive health and its associated programs in developing countries. The indicators basically stem from the accords ratified at the International Conference on Population and Development (ICPD, which was held in 1994 for the purpose of improving the reproductive health status of women, men, and adolescents throughout the world. However, working drafts and ways of approaching the subject were developed in 1996 at several meetings of representatives of the United Nations Population Fund (UNFPA, bilateral agencies, and nongovernmental organizations. The indicators are not in their definitive and final form, and it is expected that comments received from users will allow them to be improved. The indicators deal with the monitoring of progress toward the goals of the ICPD, managerial policies and procedures, family planning, maternal health, infections of the reproductive system and sexually transmitted diseases, abortion and infertility, and other demographic, social, and economic factors.

  18. Rapid Evidence Assessment of the Literature (REAL(©)): streamlining the systematic review process and creating utility for evidence-based health care.

    Science.gov (United States)

    Crawford, Cindy; Boyd, Courtney; Jain, Shamini; Khorsan, Raheleh; Jonas, Wayne

    2015-11-02

    Systematic reviews (SRs) are widely recognized as the best means of synthesizing clinical research. However, traditional approaches can be costly and time-consuming and can be subject to selection and judgment bias. It can also be difficult to interpret the results of a SR in a meaningful way in order to make research recommendations, clinical or policy decisions, or practice guidelines. Samueli Institute has developed the Rapid Evidence Assessment of the Literature (REAL) SR process to address these issues. REAL provides up-to-date, rigorous, high quality SR information on health care practices, products, or programs in a streamlined, efficient and reliable manner. This process is a component of the Scientific Evaluation and Review of Claims in Health Care (SEaRCH™) program developed by Samueli Institute, which aims at answering the question of "What works?" in health care. The REAL process (1) tailors a standardized search strategy to a specific and relevant research question developed with various stakeholders to survey the available literature; (2) evaluates the quantity and quality of the literature using structured tools and rulebooks to ensure objectivity, reliability and reproducibility of reviewer ratings in an independent fashion and; (3) obtains formalized, balanced input from trained subject matter experts on the implications of the evidence for future research and current practice. Online tools and quality assurance processes are utilized for each step of the review to ensure a rapid, rigorous, reliable, transparent and reproducible SR process. The REAL is a rapid SR process developed to streamline and aid in the rigorous and reliable evaluation and review of claims in health care in order to make evidence-based, informed decisions, and has been used by a variety of organizations aiming to gain insight into "what works" in health care. Using the REAL system allows for the facilitation of recommendations on appropriate next steps in policy, funding

  19. [The role of information and training for workers on the correct use of earplugs in assessing real noise attenuation with E-A-RfitTM system].

    Science.gov (United States)

    Cassano, Filippo; Aloise, Ingrid; Labianca, Graziano; Gaccione, Vincenzo; Mazzotta, Cosimo; Cardascia, Francesco; Garavaglia, Michela; Germano, Candida; Dentamaro, Antonella; Di Lorenzo, Luigi

    2015-07-08

    Laboratory levels of perceived noise attenuation as heard using earplugs are always higher than the real levels that can be achieved at the workplace. The employer is bound by law to supply individual hearing protection devices (HPDs), to assess their efficiency and efficacy, and also to inform and train workers on the correct use of HPDs. This study assessed the real "personal attenuation rating" (PAR) of HPDs  used by workers at the workplace, before (PAR A) and after (PAR B) specific and individual training. These values were also compared with the theoretical  "single number rating" (SNR) provided by the manufacturer. The study covered all the 65 male employees of an awnings factory, using the E-A-RfitTM computerized method, which can measure PARs, based on the difference between sound pressures recorded by an "outside" microphone and an "inside" microphone placed in the auditory canal, with earplugs inserted, before (PAR A) and after (PAR B), i.e., the specific and individual training described above. PARs B were always definitely higher than PARs A, both for all tested frequencies and the corresponding average values, which were automatically detected by E-A-RfitTM. Furthermore the same PARs B were  decidedly lower than the respective SNRs supplied by the manufacturer on the basis of laboratory assessments. These data prove that specific and individual training for workers improves the performance of earplugs, contributing to a more appropriate secondary prevention of the effects of noise on hearing; they also prove that the real attenuation recorded in workers are always lower than those supplied by the manufacturer of the devices. It is recommended that the E-A-RfitTM system, which allowed these results to be achieved objectively, should be normally used to assess exposure to noise in workers, when HPDs are worn.

  20. Quantitative assessment of hematopoietic chimerism by quantitative real-time polymerase chain reaction of sequence polymorphism systems after hematopoietic stem cell transplantation.

    Science.gov (United States)

    Qin, Xiao-ying; Li, Guo-xuan; Qin, Ya-zhen; Wang, Yu; Wang, Feng-rong; Liu, Dai-hong; Xu, Lan-ping; Chen, Huan; Han, Wei; Wang, Jing-zhi; Zhang, Xiao-hui; Li, Jin-lan; Li, Ling-di; Liu, Kai-yan; Huang, Xiao-jun

    2011-08-01

    Analysis of changes in recipient and donor hematopoietic cell origin is extremely useful to monitor the effect of hematopoietic stem cell transplantation (HSCT) and sequential adoptive immunotherapy by donor lymphocyte infusions. We developed a sensitive, reliable and rapid real-time PCR method based on sequence polymorphism systems to quantitatively assess the hematopoietic chimerism after HSCT. A panel of 29 selected sequence polymorphism (SP) markers was screened by real-time PCR in 101 HSCT patients with leukemia and other hematological diseases. The chimerism kinetics of bone marrow samples of 8 HSCT patients in remission and relapse situations were followed longitudinally. Recipient genotype discrimination was possible in 97.0% (98 of 101) with a mean number of 2.5 (1-7) informative markers per recipient/donor pair. Using serial dilutions of plasmids containing specific SP markers, the linear correlation (r) of 0.99, the slope between -3.2 and -3.7 and the sensitivity of 0.1% were proved reproducible. By this method, it was possible to very accurately detect autologous signals in the range from 0.1% to 30%. The accuracy of the method in the very important range of autologous signals below 5% was extraordinarily high (standard deviation real-time PCR method over short tandem repeat PCR chimerism assays is the absence of PCR competition and plateau biases, with demonstrated greater sensitivity and linearity. Finally, we prospectively analyzed bone marrow samples of 8 patients who received allografts and presented the chimerism kinetics of remission and relapse situations that illustrated the sensitivity level and the promising clinical application of this method. This SP-based real-time PCR assay provides a rapid, sensitive, and accurate quantitative assessment of mixed chimerism that can be useful in predicting graft rejection and early relapse.

  1. Real Property Tax Rates

    Data.gov (United States)

    Montgomery County of Maryland — The Levy Year 2012 real property tax rate dataset reflects all the rates per $100 set each year by the County Council. These rates are applied to the assessed value...

  2. Los flujos de efectivo en una economía monástica. Estudio del Arca de la Comunidad del Monasterio de Santa María la Real de Oseira (1614-1698

    Directory of Open Access Journals (Sweden)

    Elena Gallego Rodríguez

    2007-07-01

    Este artículo concluye con algunas reflexiones y un resumen de los resultados. Estos resultados nos muestran la idoneidad de la información financiera que suministra el libro de estados en función de los objetivos que presentaba el acto al que iba destinado -Capítulo General- y las decisiones que en él se tomaban. Así, el estudio prueba la vinculación entre el libro de estados y las obligaciones contributivas de la Congregación, facilitando la función de control sobre la gestión de la Media Anata en las abadías y la asignación de los repartimentos.

  3. Risk assessment methods in radiotherapy: Probabilistic safety assessment (PSA); Los metodos de analisis de riesgo en radioterapia: Analisis Probabilistico de seguridad (APS)

    Energy Technology Data Exchange (ETDEWEB)

    Ramirez Vera, M. L.; Perez Mulas, A.; Delgado, J. M.; Barrientos Ontero, M.; Somoano, F.; Alvarez Garcia, C.; Rodriguez Marti, M.

    2011-07-01

    The understanding of accidents that have occurred in radiotherapy and the lessons learned from them are very useful to prevent repetition, but there are other risks that have not been detected to date. With a view to identifying and preventing such risks, proactive methods successfully applied in other fields, such as probabilistic safety assessment (PSA), have been developed. (Author)

  4. An Assessment of the radiological vulnerability for Spanish soils; Estimacion de indices de vulnerabilidad radiologica para los suelos peninsulares espanoles

    Energy Technology Data Exchange (ETDEWEB)

    Trueba, C.; Millan, R.; Schimid, T.; Lago, C.; Gutierrez, J. [Ciemat. Madrid (Spain)

    2000-07-01

    A methodology is presented to assess the radiological vulnerability of soils, based exclusively on their pedagogical properties. The radiological vulnerability defined as the potential capacity of soils to fix or transfer deposited radiocaesium and radiostrontium to plants, is represented in terms of vulnerability indexes. Two pathways are considered, the external irradiation and their transfer through the food chain, where the top horizon and a critical depth of 60 cm is taken into account, respectively, Partial vulnerability indexes are considered for each pathway, which allows a qualitative prediction of the behaviour of the contaminants in soils Global indexes have been obtained as the sum of the partial indexes. The methodology has been applied and validated using a data base consisting of more than 2000 soil profiles selected from all over Spain. This included a pedagogical characterisation and normalisation of the different soil profiles. Results have been obtained for individual soil profiles and with the aid of a GIS, the distribution of the partial and global indexes have been presented for the most representative soil types. (Author)

  5. On the possibility of real time air quality and toxicology assessment using multi-wavelength photoacoustic spectroscopy

    Science.gov (United States)

    Ajtai, Tibor; Pinter, Mate; Utry, Noemi; Kiss-Albert, Gergely; Palagyi, Andrea; Manczinger, Laszlo; Vagvölgyi, Csaba; Szabo, Gabor; Bozoki, Zoltan

    2016-04-01

    In this study we present results of field measurement campaigns focusing on the in-situ characterization of absorption spectra and the health relevance of light absorbing carbonaceous (LAC) in the ambient. The absorption spectra is measured @ 266, 355, 532 and 1064 nm by our state-of-the-art four-wavelength photoacoustic instrument, while for health relevance the eco- cito and genotoxicity parameters were measured using standardized methodologies. We experimentally demonstrated a correlation between the toxicities and the measured absorption spectra quantified by its wavelength dependency. Based on this correlation, we present novel possibilities on real-time air quality monitoring. LAC is extensively studied not only because of its considerable climate effects but as a serious air pollutant too. Gradually increasing number of studies demonstrated experimentally that the health effect of LAC is more serious than it is expected based on its share in total atmospheric aerosol mass. Furthermore during many local pollution events LAC not only has dominancy but it is close to exclusivity. Altogether due to its climate and health effects many studies and proposed regulations focus on the physical, chemical and toxicological properties of LAC as well as on its source apportionment. Despites of its importance, there is not yet a widely accepted standard methodology for the real-time and selective identification of LAC. There are many different reasons of that: starting from its complex inherent physicochemical features including many unknown constituents, via masking effect of ambient on the inherent physicochemical properties taking place even in case of a short residence, ending with the lack of reliable instrumentation for its health or source relevant parameters. Therefore, the methodology and instrument development for selective and reliable identification of LAC is timely and important issues in climate and air quality researches. Recently, many studies demonstrated

  6. Los inmigrados

    Directory of Open Access Journals (Sweden)

    Lojze Kovačič

    2007-12-01

    Full Text Available Lojze Kovačič nació el 9 de noviembre de 1928 en Basilea, Suiza, en una familia de emigrantes, de madre alemana y padre esloveno. En 1938, cuando las autoridades suizas expulsaron del país a todos los emigrantes que no tenían ciudadanía suiza, se fue a vivir con su familia a Eslovenia, primero a Novo mesto, luego a Ljubljana donde frecuentó la escuela primaria, secundaria y la academia de pedagogía. Vivió en Ljubljana donde trabajó primero como periodista y luego como pedagogo. Murió el 1 de mayo de 2004 en la capital eslovena. Escribió obras autobiográficas y de ficción: Ljubljanske razglednice / Postales de Ljubljana (1956, Ključi mesta / Las llaves de la ciudad (1967, Deček in smrt / El niño y la muerte (1968, Sporočila v spanju – Resničnost / Mensajes en el sueño – Realidad (1972, Pet fragmentov / Cinco fragmentos (1981, Pri{leki / Los inmigrados (trilogía 1983–85, Basel / Basilea (1986, Prah / Polvo (1988, Kristalni čas / Tiempo de cristal (1990, Zgodbe s panjskih končnic / Relatos de las tablas de la colmena (1992, Knji`evna delavnica – {ola pisanja / Taller de literatura – escuela de la escritura (1997. A continuación se presentan dos fragmentos de la primera parte de la trilogía Pri{leki / Los inmigrados, una historia marcadamente autobiográfica del retorno a Eslovenia de una familia desalojada de Basilea, narrada a través de la voz de un niño de diez años, traducida al castellano por Xavier Farré y publicada por la editorial Siruela de Madrid en 2007.

  7. Neutralization Assay for Zika and Dengue Viruses by Use of Real-Time-PCR-Based Endpoint Assessment.

    Science.gov (United States)

    Wilson, Heather L; Tran, Thomas; Druce, Julian; Dupont-Rouzeyrol, Myrielle; Catton, Michael

    2017-10-01

    The global spread and infective complications of Zika virus (ZKV) and dengue virus (DENV) have made them flaviviruses of public health concern. Serological diagnosis can be challenging due to antibody cross-reactivity, particularly in secondary flavivirus infections or when there is a history of flavivirus vaccination. The virus neutralization assay is considered to be the most specific assay for measurement of anti-flavivirus antibodies. This study describes an assay where the neutralization endpoint is measured by real-time PCR, providing results within 72 h. It demonstrated 100% sensitivity (24/24 ZKV and 15/15 DENV) and 100% specificity (11/11 specimens) when testing well-characterized sera. In addition, the assay was able to determine the correct DENV serotype in 91.7% of cases. The high sensitivity and specificity of the real-time PCR neutralization assay makes it suitable to use as a confirmatory test for sera that are reactive in commercial IgM/IgG enzyme immunoassays. Results are objective and the PCR-based measurement of the neutralization endpoint lends itself to automation so that throughput may be increased in times of high demand. Copyright © 2017 American Society for Microbiology.

  8. Novel real-time 3D radiological mapping solution for ALARA maximization, D and D assessments and radiological management

    Energy Technology Data Exchange (ETDEWEB)

    Dubart, Philippe; Hautot, Felix [AREVA Group, 1 route de la Noue, Gif sur Yvette (France); Morichi, Massimo; Abou-Khalil, Roger [AREVA Group, Tour AREVA-1, place Jean Millier, Paris (France)

    2015-07-01

    Good management of dismantling and decontamination (D and D) operations and activities is requiring safety, time saving and perfect radiological knowledge of the contaminated environment as well as optimization for personnel dose and minimization of waste volume. In the same time, Fukushima accident has imposed a stretch to the nuclear measurement operational approach requiring in such emergency situation: fast deployment and intervention, quick analysis and fast scenario definition. AREVA, as return of experience from his activities carried out at Fukushima and D and D sites has developed a novel multi-sensor solution as part of his D and D research, approach and method, a system with real-time 3D photo-realistic spatial radiation distribution cartography of contaminated premises. The system may be hand-held or mounted on a mobile device (robot, drone, e.g). In this paper, we will present our current development based on a SLAM technology (Simultaneous Localization And Mapping) and integrated sensors and detectors allowing simultaneous topographic and radiological (dose rate and/or spectroscopy) data acquisitions. This enabling technology permits 3D gamma activity cartography in real-time. (authors)

  9. Novel real-time 3D radiological mapping solution for ALARA maximization, D and D assessments and radiological management

    International Nuclear Information System (INIS)

    Dubart, Philippe; Hautot, Felix; Morichi, Massimo; Abou-Khalil, Roger

    2015-01-01

    Good management of dismantling and decontamination (D and D) operations and activities is requiring safety, time saving and perfect radiological knowledge of the contaminated environment as well as optimization for personnel dose and minimization of waste volume. In the same time, Fukushima accident has imposed a stretch to the nuclear measurement operational approach requiring in such emergency situation: fast deployment and intervention, quick analysis and fast scenario definition. AREVA, as return of experience from his activities carried out at Fukushima and D and D sites has developed a novel multi-sensor solution as part of his D and D research, approach and method, a system with real-time 3D photo-realistic spatial radiation distribution cartography of contaminated premises. The system may be hand-held or mounted on a mobile device (robot, drone, e.g). In this paper, we will present our current development based on a SLAM technology (Simultaneous Localization And Mapping) and integrated sensors and detectors allowing simultaneous topographic and radiological (dose rate and/or spectroscopy) data acquisitions. This enabling technology permits 3D gamma activity cartography in real-time. (authors)

  10. STATE POLICY FUNDAMENTALS IN FORMATION OF A NATIONAL STANDARD OF "GREEN CONSTRUCTION" FOR ASSESSMENT OF ITEMS OF REAL PROPERTY

    Directory of Open Access Journals (Sweden)

    Kolchigin Mikhail Aleksandrovich

    2012-12-01

    Full Text Available The authors analyze the problem of implementation of principles of "green construction" in the Russian Federation. Despite the availability of the appropriate legislation in the field of environmental safety of construction, there are no legal, social, or economic incentives that may boost development of "green" technologies. Until recently, fundamentals of the state policy in the field of environmental protection of real estate development have not succeeded in motivating market players to implement advanced green technologies. However, recently, the government has begun motivating the construction industry towards the use of "green" technologies. The first activity is aimed at improving the legislation and updating the international voluntary certification according to BREAM and LEED standards. The result is the acceptance of the National Green Building Standard for real estate valuation that will open up new opportunities and prospects to the participants of the construction market. However, at the initial phase of implementation of "Fundamentals of the State Policy in the Field of Environmental Development of the Russian Federation", government authorities should provide their support to proponents of green buildings, including financial inflows.

  11. Real Language Meets Real Business

    Science.gov (United States)

    Muirhead, Muirhead; Schechter, Sarah

    2016-01-01

    The Real Business Language Challenge was a collaborative pilot project between Coca-Cola Enterprises (CCE) and Routes into Languages East for Year 9 and 10 pupils. It was based on CCE's award-winning Real Business Challenge, part of its highly acclaimed education programme. The Real Business Language Challenge transformed the project into a…

  12. The Development and Application of a Value-Driven Aircraft Maintenance Operations Performance Assessment Model combined with Real Options Analysis

    NARCIS (Netherlands)

    Goossens, H.G.; Beelaerts van Blokland, W.W.A.; Curran, R.

    2011-01-01

    This research paper presents the results from the development of an Aircraft Maintenance Operations Performance Assessment Model (AMOPAM). The AMOPAM is able to assess the differences in performance in between two different states or scenarios of aircraft maintenance operations and is able to

  13. Tristes, tristes guerras. Los conflictos bélicos en los álbumes ilustrados

    OpenAIRE

    López Tortosa, Carolina

    2016-01-01

    Este trabajo tiene como finalidad reflexionar sobre los álbumes ilustrados destinados a niños que tratan los conflictos bélicos. Distinguiremos cuatro grupos: álbumes de ficción, basados en hechos reales, los que se escribieron durante una guerra y, por último, la poesía ilustrada. En todos ellos analizaremos cómo se desarrolla la guerra y cómo esta involucra y afecta a diferentes grupos sociales, en especial, los niños. Además, durante todo el trabajo reflejaremos las emociones y los pensami...

  14. Real-time assessment of exposure dose to workers in radiological environments during decommissioning of nuclear facilities

    International Nuclear Information System (INIS)

    Jeong, KwanSeong; Choi, ByungSeon; Moon, JeiKwon; Hyun, Dongjun; Lee, Jonghwan; Kim, IkJune; Kim, GeunHo; Seo, JaeSeok; Jeong, SeongYoung; Lee, JungJun; Song, HaeSang; Lee, SangWha; Son, BongKi

    2014-01-01

    Highlights: • The method of exposure dose assessment to workers during decommissioning of nuclear facilities. • The environments of simulation were designed under a virtual reality. • To assess exposure dose to workers, human model was developed within a virtual reality. - Abstract: This objective of this paper is to develop a method to simulate and assess the exposure dose to workers during decommissioning of nuclear facilities. To simulate several scenarios, decommissioning environments were designed using virtual reality. To assess exposure dose to workers, a human model was also developed using virtual reality. The exposure dose was measured and assessed under the principle of ALARA in accordance with radiological environmental change. This method will make it possible to plan for the exposure dose to workers during decommissioning of nuclear facilities

  15. Improved method for considering PMU’s uncertainty and its effect on real-time stability assessment methods based on Thevenin equivalent

    DEFF Research Database (Denmark)

    Perez, Angel; Jóhannsson, Hjörtur; Østergaard, Jacob

    2015-01-01

    This article characterizes experimentally the relation between phase and magnitude error from Phasor Measurement Units (PMU) in steady state and study its effect on real-time stability assessment methods. This is achieved by a set of laboratory tests applied to four different devices, where...... a bivariate Gaussian mixture distribution was used to represent the error, obtained experimentally, and later include it in the synthesized PMU measurement using the Monte Carlo Method. Two models for including uncertainty are compared and the results show that taking into account the correlation between...

  16. Real-time assessment of perioperative behaviors in children and parents: development and validation of the perioperative adult child behavioral interaction scale.

    Science.gov (United States)

    Sadhasivam, Senthilkumar; Cohen, Lindsey L; Hosu, Liana; Gorman, Kristin L; Wang, Yu; Nick, Todd G; Jou, Jing Fang; Samol, Nancy; Szabova, Alexandra; Hagerman, Nancy; Hein, Elizabeth; Boat, Anne; Varughese, Anna; Kurth, Charles Dean; Willging, J Paul; Gunter, Joel B

    2010-04-01

    Behavior in response to distressful events during outpatient pediatric surgery can contribute to postoperative maladaptive behaviors, such as temper tantrums, nightmares, bed-wetting, and attention seeking. Currently available perioperative behavioral assessment tools have limited utility in guiding interventions to ameliorate maladaptive behaviors because they cannot be used in real time, are only intended to be used during 1 phase of the experience (e.g., perioperative), or provide only a static assessment of the child (e.g., level of anxiety). A simple, reliable, real-time tool is needed to appropriately identify children and parents whose behaviors in response to distressful events at any point in the perioperative continuum could benefit from timely behavioral intervention. Our specific aims were to (1) refine the Perioperative Adult Child Behavioral Interaction Scale (PACBIS) to improve its reliability in identifying perioperative behaviors and (2) validate the refined PACBIS against several established instruments. The PACBIS was used to assess the perioperative behaviors of 89 children aged 3 to 12 years presenting for adenotonsillectomy and their parents. Assessments using the PACBIS were made during perioperative events likely to prove distressing to children and/or parents (perioperative measurement of blood pressure, induction of anesthesia, and removal of the IV catheter before discharge). Static measurements of perioperative anxiety and behavioral compliance during anesthetic induction were made using the modified Yale Preoperative Anxiety Scale and the Induction Compliance Checklist (ICC). Each event was videotaped for later scoring using the Child-Adult Medical Procedure Interaction Scale-Short Form (CAMPIS-SF) and Observational Scale of Behavioral Distress (OSBD). Interrater reliability using linear weighted kappa (kappa(w)) and multiple validations using Spearman correlation coefficients were analyzed. The PACBIS demonstrated good to excellent

  17. A Real-Time Location-Based Services System Using WiFi Fingerprinting Algorithm for Safety Risk Assessment of Workers in Tunnels

    Directory of Open Access Journals (Sweden)

    Peng Lin

    2014-01-01

    Full Text Available This paper investigates the feasibility of a real-time tunnel location-based services (LBS system to provide workers’ safety protection and various services in concrete dam site. In this study, received signal strength- (RSS- based location using fingerprinting algorithm and artificial neural network (ANN risk assessment is employed for position analysis. This tunnel LBS system achieves an online, real-time, intelligent tracking identification feature, and the on-site running system has many functions such as worker emergency call, track history, and location query. Based on ANN with a strong nonlinear mapping, and large-scale parallel processing capabilities, proposed LBS system is effective to evaluate the risk management on worker safety. The field implementation shows that the proposed location algorithm is reliable and accurate (3 to 5 meters enough for providing real-time positioning service. The proposed LBS system is demonstrated and firstly applied to the second largest hydropower project in the world, to track workers on tunnel site and assure their safety. The results show that the system is simple and easily deployed.

  18. Development of a Real-Time Environmental Monitoring System, Life Cycle Assessment Systems, and Pollution Prevention Programs

    Science.gov (United States)

    Kocher, Walter M.

    2003-01-01

    Pollution prevention (P2) opportunities and Greening the Government (GtG) activities, including the development of the Real-Time Environmental Monitoring System (RTEMS), are currently under development at the NASA Glenn Research Center. The RTEMS project entails the ongoing development of a monitoring system which includes sensors, instruments, computer hardware and software, plus a data telemetry system.Professor Kocher has been directing the RTEMS project for more than 3 years, and the implementation of the prototype system at GRC will be a major portion of his summer effort. This prototype will provide mulitmedia environmental monitoring and control capabilities, although water quality and air emissions will be the immediate issues addressed this summer. Applications beyond those currently identified for environmental purposes will also be explored.

  19. Assessment of a new Bacteroidales marker targeting North American beaver (Castor canadensis) fecal pollution by real-time PCR.

    Science.gov (United States)

    Marti, Romain; Zhang, Yun; Tien, Yuan-Ching; Lapen, David R; Topp, Edward

    2013-11-01

    In many settings wildlife can be a significant source of fecal pathogen input into surface water. The North American beaver (Castor canadensis) is a zoonotic reservoir for several human pathogens including Cryptosporidium spp. and Giardia spp. In order to specifically detect fecal pollution by beavers, we have developed and validated a beaver-specific Bacteroidales marker, designated Beapol01, based on the 16S rRNA gene. The marker is suitable for quantifying pollution using real-time PCR. The specificity and sensitivity of the marker was excellent, Beaver signal was detected in water of a mixed-activity watershed harbouring this rodent. Overall, Beapol01 will be useful for a better understanding of fecal source inputs in drainage basins inhabited by the beaver. © 2013.

  20. Real-Time Water Quality Monitoring and Habitat Assessment in theSan Luis National Wildlife Refuge

    Energy Technology Data Exchange (ETDEWEB)

    Quinn, Nigel W.T.; Hanlon, Jeremy S.; Burns, Josephine R.; Stromayer, Karl A.K.; Jordan, Brandon M.; Ennis, Mike J.; Woolington,Dennis W.

    2005-08-28

    The project report describes a two year experiment to control wetland drainage to the San Joaquin River of California from the San Luis National Wildlife Refuge using a decision support system for real-time water quality management. This system required the installation and operation of one inlet and three drainage flow and water quality monitoring stations which allowed a simple mass balance model to be developed of the seasonally managed wetlands in the study area. Remote sensing methods were developed to document long-term trends in wetland moist soil vegetation and soil salinity in response to management options such as delaying the initiation of seasonal wetland drainage. These environmental management tools provide wetland managers with some of the tools necessary to improve salinity conditions in the San Joaquin River and improve compliance with State mandated salinity objectives without inflicting long-term harm on the wild fowl habitat resource.

  1. Functional and real-time requirements of a multisensor data fusion (MSDF) situation and threat assessment (STA) resource management (RM) system

    Science.gov (United States)

    Duquet, Jean Remi; Bergeron, Pierre; Blodgett, Dale E.; Couture, Jean; Macieszczak, Maciej; Mayrand, Michel; Chalmers, Bruce A.; Paradis, Stephane

    1998-03-01

    The Research and Development group at Lockheed Martin Canada, in collaboration with the Defence Research Establishment Valcartier, has undertaken a research project in order to capture and analyze the real-time and functional requirements of a next generation Command and Control System (CCS) for the Canadian Patrol Frigates, integrating Multi- Sensor Data Fusion (MSDF), Situation and Threat Assessment (STA) and Resource Management (RM). One important aspect of the project is to define how the use of Artificial Intelligence may optimize the performance of an integrated, real-time MSDF/STA/RM system. A closed-loop simulation environment is being developed to facilitate the evaluation of MSDF/STA/RM concepts, algorithms and architectures. This environment comprises (1) a scenario generator, (2) complex sensor, hardkill and softkill weapon models, (3) a real-time monitoring tool, (4) a distributed Knowledge-Base System (KBS) shell. The latter is being completely redesigned and implemented in-house since no commercial KBS shell could adequately satisfy all the project requirements. The closed- loop capability of the simulation environment, together with its `simulated real-time' capability, allows the interaction between the MSDF/STA/RM system and the environment targets during the execution of a scenario. This capability is essential to measure the performance of many STA and RM functionalities. Some benchmark scenarios have been selected to demonstrate quantitatively the capabilities of the selected MSDF/STA/RM algorithms. The paper describes the simulation environment and discusses the MSDF/STA/RM functionalities currently implemented and their performance as an automatic CCS.

  2. Preliminary geohydrologic conceptual model of the Los Medanos region near the Waste Isolation Pilot Plant for the purpose of performance assessment

    International Nuclear Information System (INIS)

    Brinster, K.F.

    1991-01-01

    This report describes a geohydrologic conceptual model of the northern Delaware Basin to be used in modeling three-dimensional, regional ground-water flow for assessing the performance of the Waste Isolation Pilot Plant (WIPP) in the Los Medanos region near Carlsbad, New Mexico. Geochemical and hydrological evidence indicates that flow is transient in the Rustler Formation and the Capitan aquifer in response to changing geologic, hydrologic, and climatic conditions. Before the Pleistocene, ground-water flow in the Rustler Formation was generally eastward, but uneven tilting of the Delaware Basin lowered the regional base level and formed fractures in the evaporitic sequence of rocks approximately parallel to the basin axis. Dissolution along the fractures, coupled with erosion, formed Nash Draw. Also, the drop in base level resulted in an increase in the carrying power of the Pecos River, which began incising the Capitan/aquifer near Carlsbad, New Mexico. Erosion and downcutting released hydraulic pressure that caused a reversal in Rustler ground-water flow direction near the WIPP. Flow in the Rustler west of the WIPP is toward Nash Draw and eventually toward Malaga Bend; flow south of the WIPP is toward Malaga Bend. 126 refs., 70 figs., 18 tabs

  3. Economical and environmental assessment of an optimized solar cooling system for a medium-sized benchmark office building in Los Angeles, California

    Energy Technology Data Exchange (ETDEWEB)

    Hang, Yin; Qu, Ming [School of Civil Engineering, Purdue University, CIVL G243, 550 Stadium Mall Drive, West Lafayette, IN 47907 (United States); Zhao, Fu [School of Mechanical Engineering, Purdue University (United States)

    2011-02-15

    This paper presents a systematic energetic, economical, and environmental assessment on a solar cooling system for a medium-sized office building in Los Angeles, California by means of system modeling. The studied solar cooling system primarily consists of evacuated tube solar collectors, a hot water storage tank, a single-effect LiBr-H{sub 2}O absorption chiller, and a gas-fired auxiliary heater. System performance optimization and sensitivity analysis were conducted by varying two major parameters (i.e. storage tank volume and collector area). The results suggest that a trade-off exists between economic performance indicated by the equivalent uniform annual cost (EUAC) and the energetic/environmental performance indicated by the solar fraction and CO{sub 2} reduction percentage, respectively. The cost of carbon footprint reduction was defined and served as an indicator for the overall system performance. Based on this indicator, the optimal system design could be found for a solar cooling system. The approach adapted in this study can be applied to other buildings located in different climate zones to reveal the cost and benefits of solar cooling technologies and facilitate decision-making. (author)

  4. Experimental assessment of the thermal performance of storage canister/holding fixture configurations for the Los Alamos Nuclear Materials Storage Facility

    International Nuclear Information System (INIS)

    Bernardin, J.D.; Naffziger, D.C.; Gregory, W.S.

    1997-11-01

    This report presents experimental results on the thermal performance of various nested canister configurations and canister holding fixtures to be used in the Los Alamos Nuclear Materials Storage Facility. The experiment consisted of placing a heated aluminum billet (to represent heat-generating nuclear material) inside curved- and flat-bottom canisters with and without holding plate fixtures and/or extended fin surfaces. Surface temperatures were measured at several locations on the aluminum billet, inner and outer canisters, and the holding plate fixture to assess the effectiveness of the various configurations in removing and distributing the heat from the aluminum billet. Results indicated that the curved-bottom canisters, with or without holding fixtures, were extremely ineffective in extracting heat from the aluminum billet. The larger thermal contact area provided by the flat-bottom canisters compared with the curved-bottom design, greatly enhanced the heat removal process and lowered the temperature of the aluminum billet considerably. The addition of the fixture plates to the flat-bottom canister geometry greatly enhances the heat removal rates and lowers the canister operating temperatures considerably. The addition of the fixture plates to the flat-bottom canister geometry greatly enhances the heat removal rates and lowers the canister operating temperatures considerably. Finally, the addition of extended fin surfaces to the outer flat-bottom canister positioned on a fixture plate, reduced the canister temperatures still further

  5. Floodplain Assessment for the Upper Cañon de Valle Watershed Enhancement Project in Technical Area 16 at Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Hathcock, Charles Dean [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Keller, David Charles [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Sartor, Karla A. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-10-04

    This floodplain assessment was prepared in accordance with 10 Code of Federal Regulations (CFR) 1022 Compliance with Floodplain and Wetland Environmental Review Requirements, which was promulgated to implement the U.S. Department of Energy (DOE) requirements under Executive Order 11988 Floodplain Management and Executive Order 11990 Wetlands Protection. According to 10 CFR 1022, a 100-year floodplain is defined as “the lowlands adjoining inland and coastal waters and relatively flat areas and flood prone areas of offshore islands.” In this action, DOE is proposing to control the run-on of storm water by slowing water velocity and managing sediments from the upper portions of the Cañon de Valle watershed on Los Alamos National Laboratory (LANL) property with a number of new watershed controls near and within the 100-year floodplain (hereafter floodplain). The proposed work will comply with requirements under the Settlement Agreement and Stipulated Final Compliance Order (Settlement Agreement) Number HWB-14-20.

  6. Los diarios

    Directory of Open Access Journals (Sweden)

    Alfonso Hanssen

    1967-12-01

    Full Text Available Junio 14 - Uno ha tenido el cuidado de amar exageradamente. Se extingue la pasión y se reduce en el ánima la energía. La convertimos en imágenes. La especie de rechazo. El fracaso de los sentimientos desleídos. El tedio galopante. La furia. Y el espíritu lleno y caótico. Entonces uno necesita mudarse, transportarse en la crín de la idea tropélica. Porque uno está perdido. Porque quiere navegar con mástiles rotos. Se le propone a la vida la danza dionisíaca. Extraerse uno. Someterse al éxtasis imaginativo.

  7. A real-time comparison between direct control, sequential pattern recognition control and simultaneous pattern recognition control using a Fitts' law style assessment procedure.

    Science.gov (United States)

    Wurth, Sophie M; Hargrove, Levi J

    2014-05-30

    Pattern recognition (PR) based strategies for the control of myoelectric upper limb prostheses are generally evaluated through offline classification accuracy, which is an admittedly useful metric, but insufficient to discuss functional performance in real time. Existing functional tests are extensive to set up and most fail to provide a challenging, objective framework to assess the strategy performance in real time. Nine able-bodied and two amputee subjects gave informed consent and participated in the local Institutional Review Board approved study. We designed a two-dimensional target acquisition task, based on the principles of Fitts' law for human motor control. Subjects were prompted to steer a cursor from the screen center of into a series of subsequently appearing targets of different difficulties. Three cursor control systems were tested, corresponding to three electromyography-based prosthetic control strategies: 1) amplitude-based direct control (the clinical standard of care), 2) sequential PR control, and 3) simultaneous PR control, allowing for a concurrent activation of two degrees of freedom (DOF). We computed throughput (bits/second), path efficiency (%), reaction time (second), and overshoot (%)) and used general linear models to assess significant differences between the strategies for each metric. We validated the proposed methodology by achieving very high coefficients of determination for Fitts' law. Both PR strategies significantly outperformed direct control in two-DOF targets and were more intuitive to operate. In one-DOF targets, the simultaneous approach was the least precise. The direct control was efficient in one-DOF targets but cumbersome to operate in two-DOF targets through a switch-depended sequential cursor control. We designed a test, capable of comprehensively describing prosthetic control strategies in real time. When implemented on control subjects, the test was able to capture statistically significant differences (p

  8. New approaches for the reliable in vitro assessment of binding affinity based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics.

    Science.gov (United States)

    Zeilinger, Markus; Pichler, Florian; Nics, Lukas; Wadsak, Wolfgang; Spreitzer, Helmut; Hacker, Marcus; Mitterhauser, Markus

    2017-12-01

    Resolving the kinetic mechanisms of biomolecular interactions have become increasingly important in early-phase drug development. Since traditional in vitro methods belong to dose-dependent assessments, binding kinetics is usually overlooked. The present study aimed at the establishment of two novel experimental approaches for the assessment of binding affinity of both, radiolabelled and non-labelled compounds targeting the A 3 R, based on high-resolution real-time data acquisition of radioligand-receptor binding kinetics. A novel time-resolved competition assay was developed and applied to determine the K i of eight different A 3 R antagonists, using CHO-K1 cells stably expressing the hA 3 R. In addition, a new kinetic real-time cell-binding approach was established to quantify the rate constants k on and k off , as well as the dedicated K d of the A 3 R agonist [ 125 I]-AB-MECA. Furthermore, lipophilicity measurements were conducted to control influences due to physicochemical properties of the used compounds. Two novel real-time cell-binding approaches were successfully developed and established. Both experimental procedures were found to visualize the kinetic binding characteristics with high spatial and temporal resolution, resulting in reliable affinity values, which are in good agreement with values previously reported with traditional methods. Taking into account the lipophilicity of the A 3 R antagonists, no influences on the experimental performance and the resulting affinity were investigated. Both kinetic binding approaches comprise tracer administration and subsequent binding to living cells, expressing the dedicated target protein. Therefore, the experiments resemble better the true in vivo physiological conditions and provide important markers of cellular feedback and biological response.

  9. Emergency Assessment of Debris-Flow Hazards from Basins Burned by the 2007 Ranch Fire, Ventura and Los Angeles Counties, Southern California

    Science.gov (United States)

    Cannon, Susan H.; Gartner, Joseph E.; Michael, John A.; Bauer, Mark A.; Stitt, Susan C.; Knifong, Donna L.; McNamara, Bernard J.; Roque, Yvonne M.

    2007-01-01

    INTRODUCTION The objective of this report is to present a preliminary emergency assessment of the potential for debris-flow generation from basins burned by the Ranch Fire in Ventura and Los Angeles Counties, southern California in 2007. Debris flows are among the most hazardous geologic phenomena; debris flows that followed wildfires in southern California in 2003 killed 16 people and caused tens of millions of dollars of property damage. A short period of even moderate rainfall on a burned watershed can lead to debris flows. Rainfall that is normally absorbed into hillslope soils can run off almost instantly after vegetation has been removed by wildfire. This causes much greater and more rapid runoff than is normal from creeks and drainage areas. Highly erodible soils in a burn scar allow flood waters to entrain large amounts of ash, mud, boulders, and unburned vegetation. Within the burned area and downstream, the force of rushing water, soil, and rock can destroy culverts, bridges, roadways, and buildings, potentially causing injury or death. This emergency debris-flow hazard assessment is presented as relative ranking of the predicted median volume of debris flows that can issue from basin outlets in response to 2.25 inches (57.15 mm) of rainfall over a 3-hour period. Such a storm has a 10-year return period. The calculation of debris flow volume is based on a multiple-regression statistical model that describes the median volume of material that can be expected from a recently burned basin as a function of the area burned at high and moderate severity, the basin area with slopes greater than or equal to 30 percent, and triggering storm rainfall. Cannon and others (2007) describe the methods used to generate the hazard maps. Identification of potential debris-flow hazards from burned drainage basins is necessary to issue warnings for specific basins, to make effective mitigation decisions, and to help plan evacuation timing and routes.

  10. Assessment of Clinically Suspected Tubercular Lymphadenopathy by Real-Time PCR Compared to Non-Molecular Methods on Lymph Node Aspirates.

    Science.gov (United States)

    Gupta, Vivek; Bhake, Arvind

    2018-01-01

    The diagnosis of tubercular lymphadenitis (TBLN) is challenging. This study assesses the role of diagnostic intervention with real-time PCR in clinically suspected tubercular lymphadenopathy in relation to cytology and microbiological methods. The cross-sectional study involved 214 patients, and PCR, cytology, and Ziehl-Neelsen (ZN) staining was performed on aspirates. The findings were compared with culture on Lowenstein-Jensen medium. The overall concordance of cytology and PCR, both individually and combined, was calculated. χ2 and Phi values were assessed between cytology, PCR, and culture. A cytological diagnosis of tuberculosis (TB), reactive lymphoid hyperplasia, and suppurative lymphadenitis was made in 71, 112, and 6 patients, respectively. PCR and culture were positive in 40% of the cases. Among the TBLN patients, PCR showed higher positivity in necrosis and culture showed higher positivity in necrotizing granuloma. Positive ZN staining was observed in 29.6% of the TBLN cases, with an overall positivity of 11%. PCR could additionally detect 82 cases missed by ZN staining. The overall concordance rate for either diagnostic modality, i.e., PCR or cytology, was highest (75%), and for PCR alone was 74%. Phi values were observed to be 0.47 between PCR and culture. Real-time PCR for Mycobacterium tuberculosis complex on aspirates offers a definitive and comparable diagnosis of TBLN. Including this approach as the primary investigation in the work-up of TBLN could reduce the burden of TB. © 2017 S. Karger AG, Basel.

  11. Real-time Risk Assessment for Aids to Navigation Using Fuzzy-FSA on Three-Dimensional Simulation System

    OpenAIRE

    Jinbiao Chen; Chaojian Shi; Dongxing Jia

    2014-01-01

    The risk level of the Aids to Navigation (AtoNs) can reflect the ship navigation safety level in the channel to some extent. In order to appreciate the risk level of the aids to navigation (AtoNs) in a navigation channel and to provide some decision-making suggestions for the AtoNs Maintenance and Management Department, the risk assessment index system of the AtoNs was built considering the advanced experience of IALA. Under the Formal Safety Assessment frame, taking the advantages of the fuz...

  12. Energy Recovery from the Organic Fraction of Municipal Solid Waste: A Real Options-Based Facility Assessment

    Directory of Open Access Journals (Sweden)

    Luigi Ranieri

    2018-01-01

    Full Text Available During the last years, due to the strict regulations on waste landfilling, anaerobic digestion (AD of the organic fraction of municipal solid waste (OFMSW is increasingly considered a sustainable alternative for waste stabilization and energy recovery. AD can reduce the volume of OFMSW going to landfill and produce, at the same time, biogas and compost, all at a profit. The uncertainty about the collected quantity of organic fraction, however, may undermine the economic-financial sustainability of such plants. While the flexibility characterizing some AD technologies may prove very valuable in uncertain contexts since it allows adapting plant capacity to changing environments, the investment required for building flexible systems is generally higher than the investment for dedicated equipment. Hence, an adequate justification of investments in these flexible systems is needed. This paper presents the results of a study aimed at investigating how different technologies may perform from technical, economic and financial standpoints, in presence of an uncertain organic fraction quantity to be treated. Focusing on two AD treatment plant configurations characterized by a technological process with different degree of flexibility, a real options-based model is developed and then applied to the case of the urban waste management system of the Metropolitan Area of Bari (Italy. Results show the importance of pricing the flexibility of treatment plants, which becomes a critical factor in presence of an uncertain organic fraction. Hence, it has to be taken into consideration in the design phase of these plants.

  13. Targeting a polyketide synthase gene for Aspergillus carbonarius quantification and ochratoxin A assessment in grapes using real-time PCR

    International Nuclear Information System (INIS)

    Atoui, A.; Mathieu, F.; Lebrihi, A.

    2007-01-01

    Aspergillus carbonarius is an ochratoxin producing fungus that has been considered to be responsible of the ochratoxin A (OTA) contamination in grapes and wine. In order to monitor and quantify A. carbonarius, a specific primer pair Ac12RL O TAF/Ac12RL O TAR has been designed from the acyltransferase (AT) domain of the polyketide synthase sequence Ac12RL3 to amplify 141 bp PCR product. Among the mycotoxigenic fungi tested, only A. carbonarius gave a positive result. This specific primer pair was also successfully employed in real-time PCR conjugated with SYBR Green I dye for the direct quantification of this fungus in grape samples. A positive correlation (R2 = 0.81) was found between A. carbonarius DNA content and OTA concentration in 72 grape samples, allowing for the estimation of the potential risk from OTA contamination. Consequently, this work offers a quick alternative to conventional methods of OTA quantification and mycological detection and quantification of A. carbonarius in grapes. (author)

  14. Safety surrogate histograms (SSH): A novel real-time safety assessment of dilemma zone related conflicts at signalized intersections.

    Science.gov (United States)

    Ghanipoor Machiani, Sahar; Abbas, Montasir

    2016-11-01

    Drivers' indecisiveness in dilemma zones (DZ) could result in crash-prone situations at signalized intersections. DZ is to the area ahead of an intersection in which drivers encounter a dilemma regarding whether to stop or proceed through the intersection when the signal turns yellow. An improper decision to stop by the leading driver, combined with the following driver deciding to go, can result in a rear-end collision, unless the following driver recognizes a collision is imminent and adjusts his or her behavior at or shortly after the onset of yellow. Considering the significance of DZ-related crashes, a comprehensive safety measure is needed to characterize the level of safety at signalized intersections. In this study, a novel safety surrogate measure was developed utilizing real-time radar field data. This new measure, called safety surrogate histogram (SSH), captures the degree and frequency of DZ-related conflicts at each intersection approach. SSH includes detailed information regarding the possibility of crashes, because it is calculated based on the vehicles conflicts. An example illustrating the application of the new methodology at two study sites in Virginia is presented and discussed, and a comparison is provided between SSH and other DZ-related safety surrogate measures mentioned in the literature. The results of the study reveal the efficacy of the SSH as complementary to existing surrogate measures. Copyright © 2015 Elsevier Ltd. All rights reserved.

  15. Cool City Design: Integrating Real-Time Urban Canyon Assessment into the Design Process for Chinese and Australian Cities

    Directory of Open Access Journals (Sweden)

    Marcus White

    2016-09-01

    Full Text Available Many cities are undergoing rapid urbanisation and intensification with the unintended consequence of creating dense urban fabric with deep ‘urban canyons’. Urban densification can trap longwave radiation impacting on local atmospheric conditions, contributing to the phenomena known as the Urban Heat Island (UHI. As global temperatures are predicted to increase, there is a critical need to better understand urban form and heat retention in cities and integrate analysis tools into the design decision making process to design cooler cities. This paper describes the application and validation of a novel three-dimensional urban canyon modelling approach calculating Sky View Factor (SVF, one important indicator used in the prediction of UHI. Our modified daylighting system based approach within a design modelling environment allows iterative design decision making informed by SVF on an urban design scale. This approach is tested on urban fabric samples from cities in both Australia and China. The new approach extends the applicability in the design process of existing methods by providing ‘real-time’ SVF feedback for complex three-dimensional urban scenarios. The modelling approach enables city designers to mix intuitive compositional design modelling with dynamic canyon feedback. The approach allows a greater understanding of existing and proposed urban forms and identifying potential canyon problem areas, improved decision making and design advocacy, and can potentially have an impact on cities’ temperature.

  16. Green Routing Fuel Saving Opportunity Assessment: A Case Study on California Large-Scale Real-World Travel Data

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Lei [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Holden, Jacob [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Gonder, Jeffrey D [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Wood, Eric W [National Renewable Energy Laboratory (NREL), Golden, CO (United States)

    2017-07-31

    New technologies, such as connected and automated vehicles, have attracted more and more researchers for improving the energy efficiency and environmental impact of current transportation systems. The green routing strategy instructs a vehicle to select the most fuel-efficient route before the vehicle departs. It benefits the current transportation system with fuel saving opportunity through identifying the greenest route. This paper introduces an evaluation framework for estimating benefits of green routing based on large-scale, real-world travel data. The framework has the capability to quantify fuel savings by estimating the fuel consumption of actual routes and comparing to routes procured by navigation systems. A route-based fuel consumption estimation model, considering road traffic conditions, functional class, and road grade is proposed and used in the framework. An experiment using a large-scale data set from the California Household Travel Survey global positioning system trajectory data base indicates that 31% of actual routes have fuel savings potential with a cumulative estimated fuel savings of 12%.

  17. Green Routing Fuel Saving Opportunity Assessment: A Case Study on California Large-Scale Real-World Travel Data: Preprint

    Energy Technology Data Exchange (ETDEWEB)

    Zhu, Lei; Holden, Jacob; Gonder, Jeff; Wood, Eric

    2017-07-13

    New technologies, such as connected and automated vehicles, have attracted more and more researchers for improving the energy efficiency and environmental impact of current transportation systems. The green routing strategy instructs a vehicle to select the most fuel-efficient route before the vehicle departs. It benefits the current transportation system with fuel saving opportunity through identifying the greenest route. This paper introduces an evaluation framework for estimating benefits of green routing based on large-scale, real-world travel data. The framework has the capability to quantify fuel savings by estimating the fuel consumption of actual routes and comparing to routes procured by navigation systems. A route-based fuel consumption estimation model, considering road traffic conditions, functional class, and road grade is proposed and used in the framework. An experiment using a large-scale data set from the California Household Travel Survey global positioning system trajectory data base indicates that 31% of actual routes have fuel savings potential with a cumulative estimated fuel savings of 12%.

  18. Integration of dynamic simulator for exploring WWTP. The real case of Calasparra WWTP (Murcia, Spain); Integracion de los simuladores de operacion en la explotacion de EDAR. Aplicacion a un Caso Practico: la EDAR de Calasparra

    Energy Technology Data Exchange (ETDEWEB)

    Irizar Picon, I.; Gomez San Martin, S.; Castro Gonzalez, A.; Ayesa Iturrate, E.

    2006-07-01

    This work presents an integrated decision support tool for operation of wastewater treatment full-scale plants (WWTP). Such a tool has ben developed by combining an efficient management of real data with the utilisation of dynamic simulator customised for operation of WWTP. In addition, it has been applied to a full-scale WWTP so as to demonstrate its real capabilities for predicting plant performance and for exploring new operational strategies. Finally, the system architecture was designed making use of web technologies in order to facilitate their utilisation. (Author) 10 refs.

  19. Analysing UK real estate market forecast disagreement

    OpenAIRE

    McAllister, Patrick; Newell, G.; Matysiak, George

    2005-01-01

    Given the significance of forecasting in real estate investment decisions, this paper investigates forecast uncertainty and disagreement in real estate market forecasts. Using the Investment Property Forum (IPF) quarterly survey amongst UK independent real estate forecasters, these real estate forecasts are compared with actual real estate performance to assess a number of real estate forecasting issues in the UK over 1999-2004, including real estate forecast error, bias and consensus. The re...

  20. System for integrated adherence monitoring: real-time non-adherence risk assessment in pediatric kidney transplantation.

    Science.gov (United States)

    Pai, Ahna L H; Rausch, Joseph; Tackett, Alayna; Marsolo, Keith; Drotar, Dennis; Goebel, Jens

    2012-06-01

    This study reports initial results of the development of the SIAM, a non-adherence risk assessment system for tacrolimus and sirolimus for the pediatric kidney transplant population. Forty-eight youths between 10 and 25 yr of age diagnosed with chronic kidney disease or a kidney transplant used an electronic pill bottle (EM; time stamps each bottle opening) to dispense their medication for at least 30 days or until their next clinic appointment. Youth also completed a self-report adherence measure, and standard deviations were calculated for the last four medication serum trough levels obtained for each patient. Estimation models were developed for each medication (i.e., SIAM(TACRO) and SIAM(SIRO) ) to assign weights to these clinically available adherence measures (self-report and trough levels) for the calculation of a non-adherence risk composite score. SIAM(TACRO) models included both self-report and tacrolimus trough levels and significantly predicted EM. For sirolimus, the model predictive of adherence as measured by EM consisted of the standard deviation of sirolimus trough levels only (SIAM(SIRO) ). Non-adherence risk can be effectively assessed using clinically available assessment tools. However, the best methods for using self-report and trough levels to predict non-adherence likely differ based on the medication for which adherence is being assessed. © 2012 John Wiley & Sons A/S.

  1. Assessing the Interactivity and Prescriptiveness of Faculty Professional Development Workshops: The Real-Time Professional Development Observation Tool

    Science.gov (United States)

    Olmstead, Alice; Turpen, Chandra

    2016-01-01

    Professional development workshops are one of the primary mechanisms used to help faculty improve their teaching, and draw in many STEM instructors every year. Although workshops serve a critical role in changing instructional practices within our community, we rarely assess workshops through careful consideration of how they engage faculty.…

  2. Los Alamos Climatology 2016 Update

    Energy Technology Data Exchange (ETDEWEB)

    Bruggeman, David Alan [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2017-02-10

    The Los Alamos National Laboratory (LANL or the Laboratory) operates a meteorology monitoring network to support LANL emergency response, engineering designs, environmental compliance, environmental assessments, safety evaluations, weather forecasting, environmental monitoring, research programs, and environmental restoration. Weather data has been collected in Los Alamos since 1910. Bowen (1990) provided climate statistics (temperature and precipitation) for the 1961– 1990 averaging period, and included other analyses (e.g., wind and relative humidity) based on the available station locations and time periods. This report provides an update to the 1990 publication Los Alamos Climatology (Bowen 1990).

  3. The Feasibility of Real-Time Intraoperative Performance Assessment With SIMPL (System for Improving and Measuring Procedural Learning): Early Experience From a Multi-institutional Trial.

    Science.gov (United States)

    Bohnen, Jordan D; George, Brian C; Williams, Reed G; Schuller, Mary C; DaRosa, Debra A; Torbeck, Laura; Mullen, John T; Meyerson, Shari L; Auyang, Edward D; Chipman, Jeffrey G; Choi, Jennifer N; Choti, Michael A; Endean, Eric D; Foley, Eugene F; Mandell, Samuel P; Meier, Andreas H; Smink, Douglas S; Terhune, Kyla P; Wise, Paul E; Soper, Nathaniel J; Zwischenberger, Joseph B; Lillemoe, Keith D; Dunnington, Gary L; Fryer, Jonathan P

    Intraoperative performance assessment of residents is of growing interest to trainees, faculty, and accreditors. Current approaches to collect such assessments are limited by low participation rates and long delays between procedure and evaluation. We deployed an innovative, smartphone-based tool, SIMPL (System for Improving and Measuring Procedural Learning), to make real-time intraoperative performance assessment feasible for every case in which surgical trainees participate, and hypothesized that SIMPL could be feasibly integrated into surgical training programs. Between September 1, 2015 and February 29, 2016, 15 U.S. general surgery residency programs were enrolled in an institutional review board-approved trial. SIMPL was made available after 70% of faculty and residents completed a 1-hour training session. Descriptive and univariate statistics analyzed multiple dimensions of feasibility, including training rates, volume of assessments, response rates/times, and dictation rates. The 20 most active residents and attendings were evaluated in greater detail. A total of 90% of eligible users (1267/1412) completed training. Further, 13/15 programs began using SIMPL. Totally, 6024 assessments were completed by 254 categorical general surgery residents (n = 3555 assessments) and 259 attendings (n = 2469 assessments), and 3762 unique operations were assessed. There was significant heterogeneity in participation within and between programs. Mean percentage (range) of users who completed ≥1, 5, and 20 assessments were 62% (21%-96%), 34% (5%-75%), and 10% (0%-32%) across all programs, and 96%, 75%, and 32% in the most active program. Overall, response rate was 70%, dictation rate was 24%, and mean response time was 12 hours. Assessments increased from 357 (September 2015) to 1146 (February 2016). The 20 most active residents each received mean 46 assessments by 10 attendings for 20 different procedures. SIMPL can be feasibly integrated into surgical training programs

  4. Assessment of Real-Time Time-Dependent Density Functional Theory (RT-TDDFT) in Radiation Chemistry: Ionized Water Dimer.

    Science.gov (United States)

    Chalabala, Jan; Uhlig, Frank; Slavíček, Petr

    2018-03-29

    Ionization in the condensed phase and molecular clusters leads to a complicated chain of processes with coupled electron-nuclear dynamics. It is difficult to describe such dynamics with conventional nonadiabatic molecular dynamics schemes since the number of states swiftly increases as the molecular system grows. It is therefore attractive to use a direct electron and nuclear propagation such as the real-time time-dependent density functional theory (RT-TDDFT). Here we report a RT-TDDFT benchmark study on simulations of singly and doubly ionized states of a water monomer and dimer as a prototype for more complex processes in a condensed phase. We employed the RT-TDDFT based Ehrenfest molecular dynamics with a generalized gradient approximate (GGA) functional and compared it with wave-function-based surface hopping (SH) simulations. We found that the initial dynamics of a singly HOMO ionized water dimer is similar for both the RT-TDDFT/GGA and the SH simulations but leads to completely different reaction channels on a longer time scale. This failure is attributed to the self-interaction error in the GGA functionals and it can be avoided by using hybrid functionals with large fraction of exact exchange (represented here by the BHandHLYP functional). The simulations of doubly ionized states are reasonably described already at the GGA level. This suggests that the RT-TDDFT/GGA method could describe processes following the autoionization processes such as Auger emission, while its applicability to more complex processes such as intermolecular Coulombic decay remains limited.

  5. Real-time DNA barcoding in a rainforest using nanopore sequencing: opportunities for rapid biodiversity assessments and local capacity building.

    Science.gov (United States)

    Pomerantz, Aaron; Peñafiel, Nicolás; Arteaga, Alejandro; Bustamante, Lucas; Pichardo, Frank; Coloma, Luis A; Barrio-Amorós, César L; Salazar-Valenzuela, David; Prost, Stefan

    2018-04-01

    Advancements in portable scientific instruments provide promising avenues to expedite field work in order to understand the diverse array of organisms that inhabit our planet. Here, we tested the feasibility for in situ molecular analyses of endemic fauna using a portable laboratory fitting within a single backpack in one of the world's most imperiled biodiversity hotspots, the Ecuadorian Chocó rainforest. We used portable equipment, including the MinION nanopore sequencer (Oxford Nanopore Technologies) and the miniPCR (miniPCR), to perform DNA extraction, polymerase chain reaction amplification, and real-time DNA barcoding of reptile specimens in the field. We demonstrate that nanopore sequencing can be implemented in a remote tropical forest to quickly and accurately identify species using DNA barcoding, as we generated consensus sequences for species resolution with an accuracy of >99% in less than 24 hours after collecting specimens. The flexibility of our mobile laboratory further allowed us to generate sequence information at the Universidad Tecnológica Indoamérica in Quito for rare, endangered, and undescribed species. This includes the recently rediscovered Jambato toad, which was thought to be extinct for 28 years. Sequences generated on the MinION required as few as 30 reads to achieve high accuracy relative to Sanger sequencing, and with further multiplexing of samples, nanopore sequencing can become a cost-effective approach for rapid and portable DNA barcoding. Overall, we establish how mobile laboratories and nanopore sequencing can help to accelerate species identification in remote areas to aid in conservation efforts and be applied to research facilities in developing countries. This opens up possibilities for biodiversity studies by promoting local research capacity building, teaching nonspecialists and students about the environment, tackling wildlife crime, and promoting conservation via research-focused ecotourism.

  6. Real-time web-based assessment of total population risk of future emergency department utilization: statewide prospective active case finding study.

    Science.gov (United States)

    Hu, Zhongkai; Jin, Bo; Shin, Andrew Y; Zhu, Chunqing; Zhao, Yifan; Hao, Shiying; Zheng, Le; Fu, Changlin; Wen, Qiaojun; Ji, Jun; Li, Zhen; Wang, Yong; Zheng, Xiaolin; Dai, Dorothy; Culver, Devore S; Alfreds, Shaun T; Rogow, Todd; Stearns, Frank; Sylvester, Karl G; Widen, Eric; Ling, Xuefeng B

    2015-01-13

    An easily accessible real-time Web-based utility to assess patient risks of future emergency department (ED) visits can help the health care provider guide the allocation of resources to better manage higher-risk patient populations and thereby reduce unnecessary use of EDs. Our main objective was to develop a Health Information Exchange-based, next 6-month ED risk surveillance system in the state of Maine. Data on electronic medical record (EMR) encounters integrated by HealthInfoNet (HIN), Maine's Health Information Exchange, were used to develop the Web-based surveillance system for a population ED future 6-month risk prediction. To model, a retrospective cohort of 829,641 patients with comprehensive clinical histories from January 1 to December 31, 2012 was used for training and then tested with a prospective cohort of 875,979 patients from July 1, 2012, to June 30, 2013. The multivariate statistical analysis identified 101 variables predictive of future defined 6-month risk of ED visit: 4 age groups, history of 8 different encounter types, history of 17 primary and 8 secondary diagnoses, 8 specific chronic diseases, 28 laboratory test results, history of 3 radiographic tests, and history of 25 outpatient prescription medications. The c-statistics for the retrospective and prospective cohorts were 0.739 and 0.732 respectively. Integration of our method into the HIN secure statewide data system in real time prospectively validated its performance. Cluster analysis in both the retrospective and prospective analyses revealed discrete subpopulations of high-risk patients, grouped around multiple "anchoring" demographics and chronic conditions. With the Web-based population risk-monitoring enterprise dashboards, the effectiveness of the active case finding algorithm has been validated by clinicians and caregivers in Maine. The active case finding model and associated real-time Web-based app were designed to track the evolving nature of total population risk, in a

  7. Normativa básica de la edificación «condiciones acústicas en los edificios NBE-CA-81» Real Decreto 1909/81 de 24 de julio

    Directory of Open Access Journals (Sweden)

    A., A.

    1981-05-01

    Full Text Available Esta Norma dictada por el Real Decreto 1909/81 de 24 de julio y publicada en el «B.O.E.» del 7 de septiembre de 1981 es de obligada observancia en todos ios proyectos y construcciones de edificaciones públicas y privadas.

  8. Real-time assessment of corneal endothelial cell damage following graft preparation and donor insertion for DMEK.

    Directory of Open Access Journals (Sweden)

    Maninder Bhogal

    Full Text Available To establish a method for assessing graft viability, in-vivo, following corneal transplantation.Optimization of calcein AM fluorescence and toxicity assessment was performed in cultured human corneal endothelial cells and ex-vivo corneal tissue. Descemet membrane endothelial keratoplasty grafts were incubated with calcein AM and imaged pre and post preparation, and in-situ after insertion and unfolding in a pig eye model. Global, macroscopic images of the entire graft and individual cell resolution could be attained by altering the magnification of a clinical confocal scanning laser microscope. Patterns of cell loss observed in situ were compared to those seen using standard ex-vivo techniques.Calcein AM showed a positive dose-fluorescence relationship. A dose of 2.67μmol was sufficient to allow clear discrimination between viable and non-viable areas (sensitivity of 96.6% with a specificity of 96.1% and was not toxic to cultured endothelial cells or ex-vivo corneal tissue. Patterns of cell loss seen in-situ closely matched those seen on ex-vivo assessment with fluorescence viability imaging, trypan blue/alizarin red staining or scanning electron microscopy. Iatrogenic graft damage from preparation and insertion varied between 7-35% and incarceration of the graft tissue within surgical wounds was identified as a significant cause of endothelial damage.In-situ graft viability assessment using clinical imaging devices provides comparable information to ex-vivo methods. This method shows high sensitivity and specificity, is non-toxic and can be used to evaluate immediate cell viability in new grafting techniques in-vivo.

  9. Knee ultrasound from research to real practice: a systematic literature review of adult knee ultrasound assessment feasibility studies.

    Science.gov (United States)

    Peltea, Alexandra; Berghea, Florian; Gudu, Tania; Ionescu, Ruxandra

    2016-12-05

    To identify and analyse existing data regarding knee ultrasound (US) feasibility in clinical practice. Material and methods: A systematic literature review was performed using the terms: ("knee") AND ("ultrasound" OR "ultrasonography") AND ("feasibility" OR "pilot" OR "proof of concept"). Feasibility studies regarding knee US or US aided maneuver involving knee joint, published during 2005-2015, were selected and evaluated against a complex framework constructed around mandatory key areas for feasibility studies: acceptability, demand, implementation, practicality, adaptation, integration and expansion. One hundred and fifty-nine publications were identified, of which 9 were included in the final analysis: 6 dealt with the development and implementation of novel US scores, while the rest focused on implementing MSUS in clinical practice, evaluating the usefulness of articular cartilage US assessment and the feasibility of sonography for intra-articular knee injections, respectively. Six studies quantified feasibility as time spent for the evaluation, with only two addressing areassuch as acceptability, implementation and practicality, although none of these systematically assessed all feasibility domains. Knee US feasibility is still poorly addressed; the time required for US assessment is the main area addressed. This information gap should be properly addressed in future works, in order to ensure the right place for this technique.

  10. Development and psychometric evaluation of the self-assessment of psoriasis symptoms (SAPS) - clinical trial and the SAPS - real world patient-reported outcomes.

    Science.gov (United States)

    Armstrong, April W; Banderas, Benjamin; Foley, Catherine; Stokes, Jonathan; Sundaram, Murali; Shields, Alan L

    2017-09-01

    The Self-Assessment of Psoriasis Symptoms - Clinical Trials (SAPS-CT) and SAPS - Real World (SAPS-RW) were simultaneously created to assess the experience of plaque psoriasis in two unique contexts. Qualitative and quantitative research was conducted in four phases namely concept elicitation, questionnaire construction, content evaluation and psychometric evaluation. Following concept elicitation, 18 concepts were selected to inform questionnaire construction of the SAPS-CT and SAPS-RW. To accommodate each context of use, the SAPS-CT asks respondents to rate the target symptom 'at its worst' in the 24 h prior to assessment, while the SAPS-RW asks respondents to rate the target symptom "on average" in the 7 days prior to assessment. Cognitive debriefing confirmed that patients could comprehend and provide meaningful responses to both versions and, after minor modifications, resulted in 11-item questionnaires administered in an observational study (N = 200). Results from the observational study informed further item reduction (SAPS-RW to six items and SAPS-CT to nine items) and demonstrated that scores from each were reliable (Cronbach's α > 0.90, test-retest intraclass correlation coefficient >0.70), construct valid and able to differentiate among clinically distinct groups. The SAPS-CT and SAPS-RW are content-valid PRO questionnaires capable of producing psychometrically sound scores when administered chronic to plaque psoriasis patients.

  11. Accuracy of real-time shear wave elastography in the assessment of normal liver tissue in the guinea pig (cavia porcellus).

    Science.gov (United States)

    Glińska-Suchocka, K; Kubiak, K; Spużak, J; Jankowski, M; Borusewicz, P

    2017-03-28

    Shear wave elastography is a novel technique enabling real-time measurement of the elasticity of liver tissue. The color map is superimposed on the classic ultrasound image of the assessed tissue, which enables a precise evaluation of the stiffness of the liver tissue. The aim of the study was to assess the stiffness of normal liver tissue in the guinea pig using shear wave elastography. The study was carried out on 36 guinea pigs using the SuperSonic Imagine Aixplorer scanner, and a 1 to 6 MH convex SC6-1 transducer. An ultrasound guided Try-Cut liver core needle biopsy was carried out in all the studied animals and the collected samples were examined to exclude pathological lesions. The mean liver tissue stiffness ranged from 0.89 to 5.40 kPa. We found that shear wave elastography is an easy, non-invasive technique that can be used to assess the stiffness of liver tissue. The obtained results can be used in future studies to assess the types and changes of liver tissue in the course of various types of liver disease.

  12. Feasibility of free-breathing, GRAPPA-based, real-time cardiac cine assessment of left-ventricular function in cardiovascular patients at 3 T

    International Nuclear Information System (INIS)

    Zhu, Xiaomei; Schwab, Felix; Marcus, Roy; Hetterich, Holger; Theisen, Daniel; Kramer, Harald; Notohamiprodjo, Mike; Schlett, Christopher L.; Nikolaou, Konstantin; Reiser, Maximilian F.

    2015-01-01

    Highlights: • Grappa-based real time cine cardiac MRI is feasible for assessment of left ventricular function. • Significant underestimation of systolic function, peak ejection and filling rates needs to be considered. • Heart rate is the only positive predictor of the deviation of obtained parameters. - Abstract: Objectives: To determine the feasibility of free-breathing, GRAPPA-based, real-time (RT) cine 3 T cardiac magnetic resonance imaging (MRI) with high acceleration factors for the assessment of left-ventricular function in a cohort of patients as compared to conventional segmented cine imaging. Materials and methods: In this prospective cohort study, subjects with various cardiac conditions underwent MRI involving two RT cine sequences (high resolution and low resolution) and standard segmented cine imaging. Standard qualitative and quantitative parameters of left-ventricular function were quantified. Results: Among 25 subjects, 24 were included in the analysis (mean age: 50.5 ± 21 years, 67% male, 25% with cardiomyopathy). RT cine derived quantitative parameters of volumes and left ventricular mass were strongly correlated with segmented cine imaging (intraclass correlation coefficient [ICC]: >0.72 for both RT cines) but correlation for peak ejection and filling rates were moderate to poor for both RT cines (ICC < 0.40). Similarly, RT cines significantly underestimated peak ejection and filling rates (>103.2 ± 178 ml/s). Among patient-related factors, heart rate was strongly predictive for deviation of measurements (p < 0.05). Conclusions: RT cine MRI at 3 T is feasible for qualitative and quantitative assessment of left ventricular function for low and high-resolution sequences but results in significant underestimation of systolic function, peak ejection and filling rates

  13. Real Forestry for Real Estate

    Science.gov (United States)

    Gagnon, Jennifer; Fisher, Jason

    2013-01-01

    Virginia is poised to see an unprecedented change in forest land ownership. To provide new landowners with information on sustainable forest management, we developed a two-part program, Real Forestry for Real Estate. First, we assembled New Landowner Packets, which contain a variety of sustainable forest management resources. Second, two…

  14. Sistemas en tiempo real

    OpenAIRE

    Ramón, Hugo Dionisio; Romero, Fernando

    2002-01-01

    El objetivo de esta línea de investigación es el estudio y desarrollo de aplicaciones que poseen restricciones temporales. Resulta de interés el estudio de diferentes metodologías para la especificación y desarrollo de aplicaciones en tiempo real, así como las plataformas donde dichas aplicaciones pueden ejecutarse. Se trabaja experimentalmente con distintos tipos de hardware y software entre los que pueden mencionarse placas A/D, mini-robots, máquinas multimicroprocesadores y diferentes s...

  15. A multidisciplinary approach of workload assessment in real-job situations: Investigation in the field of aerospace activities

    Directory of Open Access Journals (Sweden)

    Claudine eMélan

    2014-09-01

    Full Text Available The present contribution presents two field studies combining tools and methods from cognitive psychology and from occupational psychology in order to perform a thorough investigation of workload in employees. Cognitive load theory proposes to distinguish different load categories of working memory, in a context of instruction. Intrinsic load is inherent to the task, extraneous load refers to components of a learning environment that may be modified to reduce total load, and germane load enables schemas construction and thus efficient learning. We showed previously that this theoretical framework may be successfully extended to working memory tasks in non instructional designs. Other theoretical models, issued from the field of occupational psychology, account for an individual’s perception of work demands or requirements in the context of different psychosocial features of the (work environment. Combining these approaches is difficult as workload assessment by job-perception questionnaires explore an individual’s overall job-perception over a large time-period, whereas cognitive load investigations in working memory tasks are typically performed within short time-periods. We proposed an original methodology enabling investigation of workload and load factors in a comparable time-frame. We report two field studies investigating workload on different shift-phases and between work-shifts, with two custom-made tools. The first one enabled workload assessment by manipulating intrinsic load (task difficulty and extraneous load (time pressure in a working-memory task. The second tool was a questionnaire based on the theoretical concepts of work-demands, control and psychosocial support. Two additional dimensions suspected to contribute to job-perception, i.e. work-family conflicts and availability of human and technical resources were also explored. Results of workload assessments were discussed in light of operators’ alertness and job-performance.

  16. A multidisciplinary approach of workload assessment in real-job situations: investigation in the field of aerospace activities.

    Science.gov (United States)

    Mélan, Claudine; Cascino, Nadine

    2014-01-01

    The present contribution presents two field studies combining tools and methods from cognitive psychology and from occupational psychology in order to perform a thorough investigation of workload in employees. Cognitive load theory proposes to distinguish different load categories of working memory, in a context of instruction. Intrinsic load is inherent to the task, extraneous load refers to components of a learning environment that may be modified to reduce total load, and germane load enables schemas construction and thus efficient learning. We showed previously that this theoretical framework may be successfully extended to working memory tasks in non-instructional designs. Other theoretical models, issued from the field of occupational psychology, account for an individual's perception of work demands or requirements in the context of different psychosocial features of the (work) environment. Combining these approaches is difficult as workload assessment by job-perception questionnaires explore an individual's overall job-perception over a large time-period, whereas cognitive load investigations in working memory tasks are typically performed within short time-periods. We proposed an original methodology enabling investigation of workload and load factors in a comparable time-frame. We report two field studies investigating workload on different shift-phases and between work-shifts, with two custom-made tools. The first one enabled workload assessment by manipulating intrinsic load (task difficulty) and extraneous load (time pressure) in a working-memory task. The second tool was a questionnaire based on the theoretical concepts of work-demands, control, and psychosocial support. Two additional dimensions suspected to contribute to job-perception, i.e., work-family conflicts and availability of human and technical resources were also explored. Results of workload assessments were discussed in light of operators' alertness and job-performance.

  17. Uncertainty in real-time voltage stability assessment methods based on Thevenin equivalent due to PMU’s accuracy

    DEFF Research Database (Denmark)

    Perez, Angel; Møller, Jakob Glarbo; Jóhannsson, Hjörtur

    2014-01-01

    This article studies the influence of PMU’s accuracy in voltage stability assessment, considering the specific case of Th ́ evenin equivalent based methods that include wide-area information in its calculations. The objective was achieved by producing a set of synthesized PMU measurements from...... a time domain simulation and using the Monte Carlo method to reflect the accuracy for the PMUs. This is given by the maximum value for the Total Vector Error defined in the IEEE standard C37.118. Those measurements allowed to estimate the distribution pa- rameters (mean and standard deviation...

  18. Cobre para los muertos. Estudio arqueométrico del material metálico procedente del monumento megalítico prehistórico de Castillejo del Bonete (Terrinches, Ciudad Real

    Directory of Open Access Journals (Sweden)

    Ignacio MONTERO RUIZ

    2014-06-01

    Full Text Available Castillejo del Bonete es una cueva que fue utilizada y adaptada como monumento funerario durante la Prehistoria reciente. Abundantes piezas metálicas en óptimo estado de conservación se han recuperado de los túmulos construidos encima de la cueva, tanto en el interior de tumbas como fuera de ellas. El objetivo de este trabajo es presentar la colección metálica del yacimiento recuperada hasta finales de 2012. También el estudio arqueometalúrgico de varias de las piezas y una interpretación del conjunto en relación a su ámbito cultural y territorial. La investigación además incorpora datos inéditos de El Acequión, Albacete, para proporcionar una perspectiva comparativa sobre la procedencia del metal en la Edad del Bronce con los datos disponibles del área argárica. Las piezas metálicas son explicadas en sus respectivos contextos arqueológicos antes de ser analizadas por diferentes métodos y técnicas: isótopos de plomo, espectrometría por fluorescencia de rayos X, microscopía electrónica de barrido con microanálisis por espectrometría de dispersión de energías de rayos X, metalografía y análisis de microdureza. Los resultados revelan tipos y procesos metalúrgicos característicos del Calcolítico y fases antiguas de la Edad del Bronce. En general son piezas sin estaño pero con alto contenido en arsénico, procedentes en buena parte del área de Linares.

  19. Assessing the use of digital radiography and a real-time interactive pulmonary nodule analysis system for large population lung cancer screening

    International Nuclear Information System (INIS)

    Xu Yan; Ma Daqing; He Wen

    2012-01-01

    Rationale and objectives: To assess the use of chest digital radiograph (DR) assisted with a real-time interactive pulmonary nodule analysis system in large population lung cancer screening. Materials and methods: 346 DR/CR patient studies with corresponding CT images were selected from 12,500 patients screened for lung cancer from year 2007 to 2009. Two expert chest radiologists established CT-confirmed Gold Standard of nodules on DR/CR images with consensus. These cases were read by eight other chest radiologists (participating radiologists) first without using a real-time interactive pulmonary nodule analysis system and then re-read using the system. Performances of participating radiologists and the computer system were analyzed. Results: The computer system achieved similar performance on DR and CR images, with a detection rate of 76% and an average FPs of 2.0 per image. Before and after using the computer-aided detection system, the nodule detection sensitivities of the participating radiologists were 62.3% and 77.3% respectively, and the A z values increased from 0.794 to 0.831. Statistical analysis demonstrated statically significant improvement for the participating radiologists after using the computer analysis system with a P-value 0.05. Conclusion: The computer system could help radiologists identify more lesions, especially small ones that are more likely to be overlooked on chest DR/CR images, and could help reduce inter-observer diagnostic variations, while its FPs were easy to recognize and dismiss. It is suggested that DR/CR assisted by the real-time interactive pulmonary nodule analysis system may be an effective means to screen large populations for lung cancer.

  20. Preliminary risk assessment of the Mexican Spotted Owl under a spatially-weighted foraging regime at the Los Alamos National Laboratory

    Energy Technology Data Exchange (ETDEWEB)

    Gallegos, A.F.; Gonzales, G.J.; Bennett, K.D.; Pratt, L.E.

    1997-02-01

    The Record of Decision on the Dual Axis Radiographic Hydrodynamic Test Facility at the Los Alamos National Laboratory requires that the Department of Energy takes special precautions to protect the Mexican Spotted Owl (Strix occidentalis lucida). In order to do so, risk to the owl presented by radiological and nonradiological contaminants must be estimated. A preliminary risk assessment on the Mexican Spotted Owl in two Ecological Exposure Units (EEUs) was performed using a modified Environmental Protection Agency Quotient method, the FORTRAN model ECORSK4, and a geographic information system. Estimated doses to the owl under a spatially-weighted foraging regime were compared against toxicological reference doses generating hazard indices (HIs) and hazard quotients (HQs) for three risk source types. The average HI was 0.20 for EEU-21 and 0.0015 for EEU-40. Under the risk parameter assumptions made, hazard quotient results indicated no unacceptable risk to the owl, including a measure of cumulative effects from multiple contaminants that assumes a linear additive toxicity type. An HI of 1.0 was used as the evaluative criteria for determining the acceptability of risk. This value was exceeded (1.06) in only one of 200 simulated potential nest sites. Cesium-137, Ni, {sup 239}Pu, Al and {sup 234}U we`re among the constituents with the highest partial HQs. Improving model realism by weighting simulated owl foraging based on distance from potential nest sites decreased the estimated risk by 72% (0.5 HI units) for EEU-21 and by 97.6% (6.3E-02 HI units) for EEU-40. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, owl habitat, facility siting, and/or facility operations in order to maintain risk from contaminants at acceptably low levels.

  1. Preliminary risk assessment of the Mexican Spotted Owl under a spatially-weighted foraging regime at the Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Gallegos, A.F.; Gonzales, G.J.; Bennett, K.D.; Pratt, L.E.

    1997-02-01

    The Record of Decision on the Dual Axis Radiographic Hydrodynamic Test Facility at the Los Alamos National Laboratory requires that the Department of Energy takes special precautions to protect the Mexican Spotted Owl (Strix occidentalis lucida). In order to do so, risk to the owl presented by radiological and nonradiological contaminants must be estimated. A preliminary risk assessment on the Mexican Spotted Owl in two Ecological Exposure Units (EEUs) was performed using a modified Environmental Protection Agency Quotient method, the FORTRAN model ECORSK4, and a geographic information system. Estimated doses to the owl under a spatially-weighted foraging regime were compared against toxicological reference doses generating hazard indices (HIs) and hazard quotients (HQs) for three risk source types. The average HI was 0.20 for EEU-21 and 0.0015 for EEU-40. Under the risk parameter assumptions made, hazard quotient results indicated no unacceptable risk to the owl, including a measure of cumulative effects from multiple contaminants that assumes a linear additive toxicity type. An HI of 1.0 was used as the evaluative criteria for determining the acceptability of risk. This value was exceeded (1.06) in only one of 200 simulated potential nest sites. Cesium-137, Ni, 239 Pu, Al and 234 U we're among the constituents with the highest partial HQs. Improving model realism by weighting simulated owl foraging based on distance from potential nest sites decreased the estimated risk by 72% (0.5 HI units) for EEU-21 and by 97.6% (6.3E-02 HI units) for EEU-40. Information on risk by specific geographical location was generated, which can be used to manage contaminated areas, owl habitat, facility siting, and/or facility operations in order to maintain risk from contaminants at acceptably low levels

  2. Los estados financieros de las empresas por actividad económica medido a través del costo real del crédito y niveles de endeudamiento.

    OpenAIRE

    Simbaña Taipe, Luis Enrique

    2014-01-01

    Se analiza la interrelación existente entre las decisiones de inversión y el endeudamiento de las empresas ecuatorianas, así como los determinantes de la composición de su estructura financiera, a partir de la información financiera presentada en la Superintendencia de Compañías, durante el periodo 2002 al 2009. Para ello se analiza empíricamente un modelo lineal de datos de panel, definido por Verona et al. (2003), utilizando como variables explicativas, el tamaño de la empresa, el costo de ...

  3. Publicación de los contaminantes atmosféricos de la estación de monitoreo en tiempo real de la ciudad de Cuenca, utilizando servicios estándares OGC

    OpenAIRE

    Sellers Walden, Chester Andrew

    2013-01-01

    La contaminación del aire ambiente es una constante amenaza para la salud humana y el ambiente per se, por lo que se requiere de la definición de políticas y de la toma de decisiones respecto a la prevención, control y mitigación de los impactos de la contaminación. Para tal fin se implementan y despliegan redes de sensores que miden el estado del entorno en el que vivimos. El GAD Municipal del cantón Cuenca, y en particular la Empresa Municipal de Movilidad Transito y Trasporte (EMOV-E...

  4. Tool to assess teamwork performance in higher education Tool to assess teamwork performance in higher education Herramienta para evaluar el funcionamiento de los equipos de trabajo en entornos docentes

    Directory of Open Access Journals (Sweden)

    Carmen Jaca García

    2013-01-01

    was used with 53 teams in a Bachelor’s Degree Programme inIndustrial Engineering. In this case, the results were used to analyze whether theproposed tool is suitable for assessing teamwork effectiveness in the university context.Practical implications: This tool will serve to provide feedback to students about the acquisition of their teamwork competency throughout the course of a Bachelor’s Degree.Social implications: Teamwork is a professional ability required by a great number of organizations, and universities should incorporate the development and assessment o fteamwork skills into their degree programmes.Originality/value: Developing this competence requires different social and personalskills, which are very difficult for students to acquire only by engaging in teamwork-building activities. The crucial step of providing feedback must also be an integral partof university curricula.Objeto: En este trabajo se presenta una herramienta de evaluación del desempeño de un equipo de trabajo que permite tutorizar experiencias de aprendizaje de trabajo en equipo y retroalimentar a los estudiantes en base a unos criterios de mejora definidos.Diseño/metodología: La herramienta se ha diseñado a partir de un modelo creado a partir de una revisión bibliográfica que representa el proceso de trabajo en equipo. A partir de este modelo se ha diseñado un cuestionario que permite medir el funcionamiento de los equipos  y se ha utilizado con 53 equipos de trabajo en  el Grado en Ingeniería de Organización Industrial de Tecnun-Universidad de Navarra.Aportaciones y resultados: El análisis de los resultados de estos equipos ha permitido obtener información acerca de la idoneidad de la herramienta para valorar el funcionamiento de equipos de trabajo en el ámbito docente.Implicaciones prácticas: El uso de la herramienta a lo largo de un ciclo docente conduce a la progresiva adquisición de la competencia por parte de los alumnos.Implicaciones sociales: El trabajo en

  5. Real-world clinical applicability of pathogenicity predictors assessed on SERPINA1 mutations in alpha-1-antitrypsin deficiency.

    Science.gov (United States)

    Giacopuzzi, Edoardo; Laffranchi, Mattia; Berardelli, Romina; Ravasio, Viola; Ferrarotti, Ilaria; Gooptu, Bibek; Borsani, Giuseppe; Fra, Annamaria

    2018-06-07

    The growth of publicly available data informing upon genetic variations, mechanisms of disease and disease sub-phenotypes offers great potential for personalised medicine. Computational approaches are likely required to assess large numbers of novel genetic variants. However, the integration of genetic, structural and pathophysiological data still represents a challenge for computational predictions and their clinical use. We addressed these issues for alpha-1-antitrypsin deficiency, a disease mediated by mutations in the SERPINA1 gene encoding alpha-1-antitrypsin. We compiled a comprehensive database of SERPINA1 coding mutations and assigned them apparent pathological relevance based upon available data. 'Benign' and 'Pathogenic' mutations were used to assess performance of 31 pathogenicity predictors. Well-performing algorithms clustered the subset of variants known to be severely pathogenic with high scores. Eight new mutations identified in the ExAC database and achieving high scores were selected for characterisation in cell models and showed secretory deficiency and polymer formation, supporting the predictive power of our computational approach. The behaviour of the pathogenic new variants and consistent outliers were rationalised by considering the protein structural context and residue conservation. These findings highlight the potential of computational methods to provide meaningful predictions of the pathogenic significance of novel mutations and identify areas for further investigation. This article is protected by copyright. All rights reserved. This article is protected by copyright. All rights reserved.

  6. Onboard tagging for real-time quality assessment of photoplethysmograms acquired by a wireless reflectance pulse oximeter.

    Science.gov (United States)

    Li, Kejia; Warren, Steve; Natarajan, Balasubramaniam

    2012-02-01

    Onboard assessment of photoplethysmogram (PPG) quality could reduce unnecessary data transmission on battery-powered wireless pulse oximeters and improve the viability of the electronic patient records to which these data are stored. These algorithms show promise to increase the intelligence level of former "dumb" medical devices: devices that acquire and forward data but leave data interpretation to the clinician or host system. To this end, the authors have developed a unique onboard feature detection algorithm to assess the quality of PPGs acquired with a custom reflectance mode, wireless pulse oximeter. The algorithm uses a Bayesian hypothesis testing method to analyze four features extracted from raw and decimated PPG data in order to determine whether the original data comprise valid PPG waveforms or whether they are corrupted by motion or other environmental influences. Based on these results, the algorithm further calculates heart rate and blood oxygen saturation from a "compact representation" structure. PPG data were collected from 47 subjects to train the feature detection algorithm and to gauge their performance. A MATLAB interface was also developed to visualize the features extracted, the algorithm flow, and the decision results, where all algorithm-related parameters and decisions were ascertained on the wireless unit prior to transmission. For the data sets acquired here, the algorithm was 99% effective in identifying clean, usable PPGs versus nonsaturated data that did not demonstrate meaningful pulsatile waveshapes, PPGs corrupted by motion artifact, and data affected by signal saturation.

  7. Assessing the resilience of a real-world social-ecological system: lessons from a multidisciplinary evaluation of a South African pastoral system

    Directory of Open Access Journals (Sweden)

    Anja Linstädter

    2016-09-01

    Full Text Available In the past decades, social-ecological systems (SESs worldwide have undergone dramatic transformations with often detrimental consequences for livelihoods. Although resilience thinking offers promising conceptual frameworks to understand SES transformations, empirical resilience assessments of real-world SESs are still rare because SES complexity requires integrating knowledge, theories, and approaches from different disciplines. Taking up this challenge, we empirically assess the resilience of a South African pastoral SES to drought using various methods from natural and social sciences. In the ecological subsystem, we analyze rangelands' ability to buffer drought effects on forage provision, using soil and vegetation indicators. In the social subsystem, we assess households' and communities' capacities to mitigate drought effects, applying agronomic and institutional indicators and benchmarking against practices and institutions in traditional pastoral SESs. Our results indicate that a decoupling of livelihoods from livestock-generated income was initiated by government interventions in the 1930s. In the post-apartheid phase, minimum-input strategies of herd management were adopted, leading to a recovery of rangeland vegetation due to unintentionally reduced stocking densities. Because current livelihood security is mainly based on external monetary resources (pensions, child grants, and disability grants, household resilience to drought is higher than in historical phases. Our study is one of the first to use a truly multidisciplinary resilience assessment. Conflicting results from partial assessments underline that measuring narrow indicator sets may impede a deeper understanding of SES transformations. The results also imply that the resilience of contemporary, open SESs cannot be explained by an inward-looking approach because essential connections and drivers at other scales have become relevant in the globalized world. Our study thus has

  8. Real analysis

    CERN Document Server

    McShane, Edward James

    2013-01-01

    This text surveys practical elements of real function theory, general topology, and functional analysis. Discusses the maximality principle, the notion of convergence, the Lebesgue-Stieltjes integral, function spaces and harmonic analysis. Includes exercises. 1959 edition.

  9. Los límites de la ausencia. Un ensayo sobre historia de las ideas: José Aricó, Leopoldo Zea y Carlos Real de Azúa

    Directory of Open Access Journals (Sweden)

    Ximena Espeche

    2017-06-01

    Full Text Available I propose reading José Aricó’s “Marx y América Latina” as a work in which the author discusses Leopoldo Zea´s proposals to study the history of ideas in such a way that it also relates to Carlos Real de Azúa´s approaches: the obsessions and terms of a possible “esoteric history” or a “philosophical research”.

  10. Regional meeting for the Americas assesses progress against rotavirus Reunión regional para las Américas evalúa el progreso contra los rotavirus

    Directory of Open Access Journals (Sweden)

    2004-01-01

    Full Text Available La diarrea provocada por la infección por rotavirus es una de las principales causas de morbilidad y mortalidad en el mundo. Los rotavirus ocasionan un total de alrededor de 111 millones de casos de diarrea y 440 000 muertes, 82% de ellas en países en desarrollo. Solo en la Región de las Américas, los rotavirus causan aproximadamente 75 000 ingresos hospitalarios y 15 000 muertes cada año. Con el objetivo de evaluar la marcha de la lucha contra los rotavirus en la Región, a principios de septiembre de 2003 se celebró en Lima, Perú, una reunión cuyos participantes examinaron la información epidemiológica, debatieron acerca de los adelantos alcanzados en el desarrollo de nuevas vacunas contra rotavirus y describieron sus experiencias con la vigilancia de la infección rotavírica. En los próximos años pueden aparecer en el mercado varias vacunas, entre ellas Rotarix (GlaxoSmithKline y RotaTeq (Merck. Ambas vacunas ya han pasado exitosamente por los estudios de fases I y II y en estos momentos se llevan a cabo extensos estudios de fase III. No obstante, aún no se conoce lo suficiente acerca del impacto económico de la enfermedad, la efectividad en función del costo que pueda llegar a alcanzar la vacunación y la vigilancia de los rotavirus en el laboratorio. La reunión realizada en Lima generó varias recomendaciones, entre ellas algunas de carácter general acerca de los estudios epidemiológicos sobre rotavirus, la metodología de los estudios de corte económico y una base de datos para su vigilancia. En relación con los laboratorios y las técnicas analíticas, las recomendaciones se centraron en las redes de laboratorios, el mejor momento para recolectar las muestras de heces y la manera de almacenar y procesar esas muestras.

  11. Real Time Assessment of Potable Water Quality in Distribution Network based on Low Cost Multi-Sensor Array

    Science.gov (United States)

    Bhardwaj, Jyotirmoy; Gupta, Karunesh K.; Khatri, Punit

    2018-03-01

    New concepts and techniques are replacing traditional methods of water quality parameters measurement systems. This paper proposed a new way of potable water quality assessment in distribution network using Multi Sensor Array (MSA). Extensive research suggests that following parameters i.e. pH, Dissolved Oxygen (D.O.), Conductivity, Oxygen Reduction Potential (ORP), Temperature and Salinity are most suitable to detect overall quality of potable water. Commonly MSA is not an integrated sensor array on some substrate, but rather comprises a set of individual sensors measuring simultaneously different water parameters all together. Based on research, a MSA has been developed followed by signal conditioning unit and finally, an algorithm for easy user interfacing. A dedicated part of this paper also discusses the platform design and significant results. The Objective of this proposed research is to provide simple, efficient, cost effective and socially acceptable means to detect and analyse water bodies regularly and automatically.

  12. Valoración Biogeográfica de los Paisajes Vegetales de Las Bardenas Reales de Navarra a través de la Metodología LANBIOEVA

    Directory of Open Access Journals (Sweden)

    Pedro José Lozano-Valencia

    2017-12-01

    Full Text Available El territorio de las Bardenas de Navarra configura uno de los paisajes más originales e infrecuentes de Europa. El relieve tabular estructural del Terciario ha sido modelado mayoritariamente en forma de badlands en un contexto climático de precipitaciones escasas y concentradas, temperaturas rigurosas tanto en invierno como en verano y vientos persistentes. Este contexto ambiental configura un paisaje vegetal de carácter estepario y con ciertas reminiscencias de zonas áridas o semiáridas. Es precisamente este interés el que nos lleva a caracterizar y valorar sus agrupaciones vegetales a través de la metodología LANBIOEVA. El método se aplica de forma sistemática de manera que las evaluaciones para cada uno de los criterios y subcriterios puedan ser comparadas con las obtenidas durante más de 25 años en otros ámbitos y formaciones a escala global. Destacan con valoraciones altas el pinar de Pinus halepensis y, sobre todo, el carrascal de Quercus ilex ssp. rotundifolia. Por su parte, las puntuaciones más bajas se registran para el coscojar de Quercus coccifera.

  13. Moving from laboratory to real life conditions: Influence on the assessment of variability and stability of gait.

    Science.gov (United States)

    Tamburini, Paola; Storm, Fabio; Buckley, Chris; Bisi, Maria Cristina; Stagni, Rita; Mazzà, Claudia

    2018-01-01

    The availability of wearable sensors allows shifting gait analysis from the traditional laboratory settings, to daily life conditions. However, limited knowledge is available about whether alterations associated to different testing environment (e.g. indoor or outdoor) and walking protocols (e.g. free or controlled), result from actual differences in the motor behaviour of the tested subjects or from the sensitivity to these changes of the indexes adopted for the assessment. In this context, it was hypothesized that testing environment and walking protocols would not modify motor control stability in the gait of young healthy adults, who have a mature and structured gait pattern, but rather the variability of their motor pattern. To test this hypothesis, data from trunk and shank inertial sensors were collected from 19 young healthy participants during four walking tasks in different environments (indoor and outdoor) and in both controlled (i.e. following a predefined straight path) and free conditions. Results confirmed what hypothesized: variability indexes (Standard deviation, Coefficient of variation and Poincaré plots) were significantly influenced by both environment and walking conditions. Stability indexes (Harmonic ratio, Short term Lyapunov exponents, Recurrence quantification analysis and Sample entropy), on the contrary, did not highlight any change in the motor control. In conclusion, this study highlighted an influence of environment and testing condition on the assessment of specific characteristics of gait (i.e. variability and stability). In particular, for young healthy adults, both environment and testing conditions affect gait variability indexes, whereas neither affect gait stability indexes. Copyright © 2017. Published by Elsevier B.V.

  14. Near Real-Time Flood Monitoring and Impact Assessment Systems. Chapter 6; [Case Study: 2011 Flooding in Southeast Asia

    Science.gov (United States)

    Ahamed, Aakash; Bolten, John; Doyle, Colin; Fayne, Jessica

    2016-01-01

    Floods are the costliest natural disaster, causing approximately 6.8 million deaths in the twentieth century alone. Worldwide economic flood damage estimates in 2012 exceed $19 Billion USD. Extended duration floods also pose longer term threats to food security, water, sanitation, hygiene, and community livelihoods, particularly in developing countries. Projections by the Intergovernmental Panel on Climate Change (IPCC) suggest that precipitation extremes, rainfall intensity, storm intensity, and variability are increasing due to climate change. Increasing hydrologic uncertainty will likely lead to unprecedented extreme flood events. As such, there is a vital need to enhance and further develop traditional techniques used to rapidly assess flooding and extend analytical methods to estimate impacted population and infrastructure. Measuring flood extent in situ is generally impractical, time consuming, and can be inaccurate. Remotely sensed imagery acquired from space-borne and airborne sensors provides a viable platform for consistent and rapid wall-to-wall monitoring of large flood events through time. Terabytes of freely available satellite imagery are made available online each day by NASA, ESA, and other international space research institutions. Advances in cloud computing and data storage technologies allow researchers to leverage these satellite data and apply analytical methods at scale. Repeat-survey earth observations help provide insight about how natural phenomena change through time, including the progression and recession of floodwaters. In recent years, cloud-penetrating radar remote sensing techniques (e.g., Synthetic Aperture Radar) and high temporal resolution imagery platforms (e.g., MODIS and its 1-day return period), along with high performance computing infrastructure, have enabled significant advances in software systems that provide flood warning, assessments, and hazard reduction potential. By incorporating social and economic data

  15. A GIS-based generic real-time risk assessment framework and decision tools for chemical spills in the river basin.

    Science.gov (United States)

    Jiang, Jiping; Wang, Peng; Lung, Wu-seng; Guo, Liang; Li, Mei

    2012-08-15

    This paper presents a generic framework and decision tools of real-time risk assessment on Emergency Environmental Decision Support System for response to chemical spills in river basin. The generic "4-step-3-model" framework is able to delineate the warning area and the impact on vulnerable receptors considering four types of hazards referring to functional area, societal impact, and human health and ecology system. Decision tools including the stand-alone system and software components were implemented on GIS platform. A detailed case study on the Songhua River nitrobenzene spill illustrated the goodness of the framework and tool Spill first responders and decision makers of catchment management will benefit from the rich, visual and dynamic hazard information output from the software. Copyright © 2012 Elsevier B.V. All rights reserved.

  16. A pilot study investigating the feasibility of symptom assessment manager (SAM), a Web-based real-time tool for monitoring challenging behaviors.

    Science.gov (United States)

    Loi, Samantha M; Wanasinghage, Sangeeth; Goh, Anita; Lautenschlager, Nicola T; Darby, David G; Velakoulis, Dennis

    2018-04-01

    Improving and minimizing challenging behaviors seen in psychiatric conditions, including behavioral and psychological symptoms of dementia are important in the care of people with these conditions. Yet there is a lack of systematic evaluation of these as a part of routine clinical care. The Neuropsychiatric Inventory is a validated and reliable tool for rating the severity and disruptiveness of challenging behaviors. We report on the evaluation of a Web-based symptom assessment manager (SAM), designed to address the limitation of previous tools using some of the Neuropsychiatric Inventory functions, to monitor behaviors by staff caring for people with dementia and other psychiatric conditions in inpatient and residential care settings. The SAM was piloted in an 8-bed inpatient neuropsychiatry unit over 5 months. Eleven nurses and 4 clinicians were trained in usage of SAM. Primary outcomes were usage of SAM and perceived usability, utility, and acceptance of SAM. Secondary outcomes were the frequencies of documented behavior. Usage data were analyzed using chi-square and logistic regression analyses. The SAM was used for all admitted patients regardless of diagnosis, with a usage rate of 64% for nurses regularly employed in the unit. Staff provided positive feedback regarding the utility of SAM. The SAM appeared to offer individualized behavior assessment by providing a quick, structured, and standardized platform for assessing behavior in a real-world setting. Further research would involve trialing SAM with more staff in alternative settings such as in home or residential care settings. Copyright © 2017 John Wiley & Sons, Ltd.

  17. Comparison of Optomap ultrawide-field imaging versus slit-lamp biomicroscopy for assessment of diabetic retinopathy in a real-life clinic

    Directory of Open Access Journals (Sweden)

    Purbrick RMJ

    2014-07-01

    Full Text Available Robert M J Purbrick, Shahrnaz Izadi, Ankur Gupta, N Victor Chong Oxford Eye Hospital, John Radcliffe Hospital, Oxford, UK Purpose: We aimed to assess the agreement between clinical assessment of diabetic retinopathy and Optomap ultrawide-field imaging (UWFI in a real-life clinic setting. Methods: Structured examination findings, from diabetic patients attending routine medical retina clinics in July 2011, were retrospectively compared with the grade obtained from Optomap UWFI images, graded independently by two ophthalmologists, taken at the same visit. Results: A total of 84 eyes (42 patients were examined, and 74 eyes (37 patients were suitable for analysis. The hospital Eye Service slit-lamp biomicroscopy grades for retinopathy were: no diabetic retinopathy in zero eyes; background retinopathy in 21 eyes; preproliferative retinopathy in 34 eyes; and proliferative retinopathy in 19 eyes. For retinopathy, the agreement between the Optomap UWFI and clinical grading was moderate for both graders (κ=0.57 and κ=0.63, and there was almost perfect agreement between the two graders (κ=0.92. The clinical grades for the presence of photocoagulation scars were: no photocoagulation scars in 46 eyes and photocoagulation scars visible in 28 eyes, indicating substantial agreement between the Optomap UWFI and clinical grading for both graders (κ=0.73 and κ=0.64. There were two instances where proliferative retinopathy was documented clinically but graded as preproliferative by both graders of Optomap UWFI. These were investigated, and neither patient required treatment, ie, the difference in retinopathy grade would not have affected the patient outcomes. Conclusion: This study demonstrated moderate agreement between Optomap UWFI and hospital slit-lamp biomicroscopy grading of patients’ retinopathy in a real-life medical retina clinic setting. The authors believe that Optomap UWFI is, not only a very useful adjunct to clinical examination in terms of

  18. Los árboles

    Directory of Open Access Journals (Sweden)

    Jaime Paredes Pardo

    1964-09-01

    Full Text Available Los árboles son hijos del viento que transporta las semillas. En los valles anda de prisa, tanto que a veces alcanza a los trenes y a la melena de los caballos que espanta la algarabía de los pasajeros. Como los trenes, el viento tiene una frente de humo. De niebla como las montañas. ¿Pensará el viento?

  19. Personalized risk communication for personalized risk assessment: Real world assessment of knowledge and motivation for six mortality risk measures from an online life expectancy calculator.

    Science.gov (United States)

    Manuel, Douglas G; Abdulaziz, Kasim E; Perez, Richard; Beach, Sarah; Bennett, Carol

    2018-01-01

    In the clinical setting, previous studies have shown personalized risk assessment and communication improves risk perception and motivation. We evaluated an online health calculator that estimated and presented six different measures of life expectancy/mortality based on a person's sociodemographic and health behavior profile. Immediately after receiving calculator results, participants were invited to complete an online survey that asked how informative and motivating they found each risk measure, whether they would share their results and whether the calculator provided information they need to make lifestyle changes. Over 80% of the 317 survey respondents found at least one of six healthy living measures highly informative and motivating, but there was moderate heterogeneity regarding which measures respondents found most informative and motivating. Overall, health age was most informative and life expectancy most motivating. Approximately 40% of respondents would share the results with their clinician (44%) or social networks (38%), although the information they would share was often different from what they found informative or motivational. Online personalized risk assessment allows for a more personalized communication compared to historic paper-based risk assessment to maximize knowledge and motivation, and people should be provided a range of risk communication measures that reflect different risk perspectives.

  20. Assessment of Left Ventricular Function and Mass on Free-Breathing Compressed Sensing Real-Time Cine Imaging.

    Science.gov (United States)

    Kido, Tomoyuki; Kido, Teruhito; Nakamura, Masashi; Watanabe, Kouki; Schmidt, Michaela; Forman, Christoph; Mochizuki, Teruhito

    2017-09-25

    Compressed sensing (CS) cine magnetic resonance imaging (MRI) has the advantage of being inherently insensitive to respiratory motion. This study compared the accuracy of free-breathing (FB) CS and breath-hold (BH) standard cine MRI for left ventricular (LV) volume assessment.Methods and Results:Sixty-three patients underwent cine MRI with both techniques. Both types of images were acquired in stacks of 8 short-axis slices (temporal/spatial resolution, 41 ms/1.7×1.7×6 mm 3 ) and compared for ejection fraction, end-diastolic and systolic volumes, stroke volume, and LV mass. Both BH standard and FB CS cine MRI provided acceptable image quality for LV volumetric analysis (score ≥3) in all patients (4.7±0.5 and 3.7±0.5, respectively; Pcine MRI (median, IQR: BH standard, 83.8 mL, 64.7-102.7 mL; FB CS, 79.0 mL, 66.0-101.0 mL; P=0.0006). The total acquisition times for BH standard and FB CS cine MRI were 113±7 s and 24±4 s, respectively (Pcine MRI is a clinically useful alternative to BH standard cine MRI in patients with impaired BH capacity.

  1. A method of assessing the efficacy of hand sanitizers: use of real soil encountered in the food service industry.

    Science.gov (United States)

    Charbonneau, D L; Ponte, J M; Kochanowski, B A

    2000-04-01

    In many outbreaks of foodborne illness, the food worker has been implicated as the source of the infection. To decrease the likelihood of cross-contamination, food workers must clean and disinfect their hands frequently. To ensure their effectiveness, hand disinfectants should be tested using rigorous conditions that mimic normal use. Currently, several different methods are used to assess the efficacy of hand disinfectants. However, most of these methods were designed with the health care worker in mind and do not model the specific contamination situations encountered by the food worker. To fill this void, we developed a model that uses soil from fresh meat and a means of quantifying bacteria that is encountered and transferred during food preparation activities. Results of studies using various doses of para-chloro-meta-xylenol and triclosan confirm that the method is reproducible and predictable in measuring the efficacy of sanitizers. Consistent, dose-dependent results were obtained with relatively few subjects. Other studies showed that washing hands with a mild soap and water for 20 s was more effective than applying a 70% alcohol hand sanitizer.

  2. The attorneys of the Royal Chancery of Valladolid and their Montepío. Difficulties and problems involved in a forced formula for social welfare and sociability Los Procuradores de la Real Chancillería de Valladolid y su Montepío. Dificultades y problemas de una fórmula de previsión y sociabilidad forzada

    Directory of Open Access Journals (Sweden)

    Margarita TORREMOCHA HERNÁNDEZ

    2012-05-01

    Full Text Available The Enlightenment fostered the disappearance of trade and professional guilds to make way for new forms of a secular nature that were charitable funds for dependents or «Montepíos». The professionals of the royal courts instituted these forms of social welfare, established primarily for the aid of widows and orphans. These new partnerships lacked the socio-religious status of the previous formulas, yet did not take on the spirit of social culture of the subsequent mutual aid associations. These absences contributed to their short existence, but it was actually the economic factor that led to the disappearance of many «Montepíos». Attorneys and Agents of the Royal Chancery founded a «Montepío» in 1780 which had trouble surviving even before the end of the decade. The measures embraced to overcome the economic failures and human defections say much about the shortcomings of this method of forced sociability.Los ilustrados promovieron la desaparición de las cofradías gremiales y profesionales, para dejar paso a fórmulas nuevas de carácter laico denominadas Montepíos. Los profesionales de los tribunales reales instituyeron estas fórmulas de previsión; establecidas fundamentalmente para el socorro tras la defunción a viudas y huérfanos. Estas nuevas asociaciones carecían de la condición socio-religioso de las anteriores, y no desarrollaron el carácter de cultura social de las posteriores asociaciones de socorros mutuos. Tales lagunas contribuyeron a su corta existencia, pero sobre todo fue el factor económico lo que condujo a no pocos Montepíos a su desaparición. Los Procuradores y Agentes de la real Chancillería fundaron en 1780 un Montepío que antes de terminar la década ya tenía problemas para sobrevivir. Las medidas adoptadas para subsanar las quiebras económicas y las defecciones humanas, dicen mucho sobre las deficiencias de esta fórmula de sociabilidad forzada.

  3. Materials accounting at Los Alamos National Laboratory

    International Nuclear Information System (INIS)

    Erkkila, B.H.; Roberts, N.J.

    1989-01-01

    This presentation gives an overview of the accounting system used at the Los Alamos National Laboratory by the Los Alamos Nuclear Material Accounting and Safeguards System (MASS). This system processes accounting data in real time for bulk materials, discrete items, and materials undergoing dynamic processing. The following topics are covered in this chapter: definitions; nuclear material storage; nuclear material storage; computer system; measurement control program; inventory differences; and current programs and future plans

  4. Summary of the 2010 assessment on medium- to low-temperature geothermal resources in Mexico; Resumen de la evaluacion 2010 de los recursos geotermicos mexicanos de temperatura intermedia a baja

    Energy Technology Data Exchange (ETDEWEB)

    Iglesias, Eduardo R.; Torres, Rodolfo J.; Martinez Estrella, J. Ignacio; Reyes Picasso, Neftali [Instituto de Investigaciones Electricas, Cuernavaca, Morelos (Mexico)]. E-mail: iglesias@iie.org.mx

    2011-07-15

    In 2003 we published our first assessment of the medium- to low-temperature (T {<=} 200 degrees Celsius) Mexican geothermal resources. The assessment was based on a database of 1,358 geothermal manifestations (surface manifestations, e.g. springs, fumaroles, water wells, etc.) identified at that time. Due to a lack of information on one or more relevant parameters, such as geographical coordinates, reservoir or surface temperatures, types of fluid, etc., that assessment included only about 30% of the geothermal manifestations in the database. Since then our group has increased significantly the amount of information in the database, using field work and data compilation from different sources. We have developed a database linked with a Geographical Information System (GIS). This work presents an updated assessment of the medium- to low-temperature Mexican geothermal resources based on our current database, which includes 2,361 geothermal manifestations. As before, we have relied on the volume method and Montecarlo simulations to estimate geothermal resources and their uncertainties for each identified geothermal system. These geothermal systems very often include more than one geothermal manifestation, generally increasing the reliability of the individual estimations. In all, we estimated the geothermal resources of 918 individual geothermal systems which included 1,797 geothermal manifestations (as before, a significant fraction of the identified manifestations lack relevant information) located in 26 of the 32 Mexican States. In most cases these resources would be classified as inferred resources, according to the Australian Geothermal Code. We then added the inferred thermal-energy statistical distributions of the 918 geothermal systems by Montecarlo simulation, obtaining the total estimated geothermal resources of the 26 Mexican States and its uncertainty. With the resulting statistical distribution, we estimated the total-thermal energy stored in the 918

  5. Getting real with real options

    OpenAIRE

    M. R Grasselli

    2006-01-01

    We apply a utility-based method to obtain the value of a finite-time investment opportunity when the underlying real asset is not perfectly correlated to a traded financial asset. Using a discrete-time algorithm to calculate the indifference price for this type of real option, we present numerical examples for the corresponding investment thresholds, in particular highlighting their dependence with respect to correlation and risk aversion.