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Sample records for asm montreal chapter

  1. Activated sludge models ASM1, ASM2, ASM2d and ASM3

    DEFF Research Database (Denmark)

    Henze, Mogens; Gujer, W.; Mino, T.

    This book has been produced to give a total overview of the Activated Sludge Model (ASM) family at the start of 2000 and to give the reader easy access to the different models in their original versions. It thus presents ASM1, ASM2, ASM2d and ASM3 together for the first time.Modelling of activated...... sludge processes has become a common part of the design and operation of wastewater treatment plants. Today models are being used in design, control, teaching and research.ContentsASM3: Introduction, Comparison of ASM1 and ASM3, ASM3: Definition of compounds in the model, ASM3: Definition of processes...... in the Model, ASM3: Stoichiometry, ASM3: Kinetics, Limitations of ASM3, Aspects of application of ASM3, ASM3C: A Carbon based model, Conclusion ASM 2d: Introduction, Conceptual Approach, ASM 2d, Typical Wastewater Characteristics and Kinetic and Stoichiometric Constants, Limitations, Conclusion ASM 2...

  2. Activated sludge models ASM1, ASM2, ASM2d and ASM3

    DEFF Research Database (Denmark)

    Henze, Mogens; Gujer, W.; Mino, T.

    sludge processes has become a common part of the design and operation of wastewater treatment plants. Today models are being used in design, control, teaching and research.ContentsASM3: Introduction, Comparison of ASM1 and ASM3, ASM3: Definition of compounds in the model, ASM3: Definition of processes...... in the Model, ASM3: Stoichiometry, ASM3: Kinetics, Limitations of ASM3, Aspects of application of ASM3, ASM3C: A Carbon based model, Conclusion ASM 2d: Introduction, Conceptual Approach, ASM 2d, Typical Wastewater Characteristics and Kinetic and Stoichiometric Constants, Limitations, Conclusion ASM 2...... Oxidation Nitrification and Denitrification, Characterization of Wastewater and Estimation of Parameter Values, Typical Parameter Ranges, Default Values, and Effects of Environmental Factors, Assumptions, Restrictions and Constraints, Implementation of the Activated Sludge Model...

  3. Montreal Modern

    DEFF Research Database (Denmark)

    Handberg, Kristian

    2015-01-01

    Through analyses of the retro scenes in Montreal, Canada, the article discusses retro culture’s role as cultural memory. It is shown how Montreal’s cultural identity is formed by memories of modern culture such as the Red-light and Sin City reputation of the illicit nightlife of the 1940s and 1950s......, and the space age modernism of the 1960s following the Expo 67 and Quebec’s Quiet Revolution. This is reflected in the city’s thriving retro culture through the study of two groups of retro shops. In circulating specific memories and objects in a specific context, retro is an important negotiation of the past...

  4. Activated sludge models ASM1, ASM2, ASM2d and ASM3

    DEFF Research Database (Denmark)

    Henze, Mogens; Gujer, W.; Mino, T.

    This book has been produced to give a total overview of the Activated Sludge Model (ASM) family at the start of 2000 and to give the reader easy access to the different models in their original versions. It thus presents ASM1, ASM2, ASM2d and ASM3 together for the first time.Modelling of activated......: Introduction, ASM 2, Typical Wastewater Characteristics and Kinetic and Stoichiometric Constants, Wastewater Characterization for Activated Sludge Processes, Calibration of the ASM 2, Model Limitations, Conclusion, Bibliography ASM 1: Introduction, Method of Model Presentation, Model Incorporating Carbon...... Oxidation Nitrification and Denitrification, Characterization of Wastewater and Estimation of Parameter Values, Typical Parameter Ranges, Default Values, and Effects of Environmental Factors, Assumptions, Restrictions and Constraints, Implementation of the Activated Sludge Model...

  5. Cisco ASM Router

    CERN Multimedia

    2001-01-01

    One of the two "ASM/2-32EM" boxes installed in 1988, from "Cisco Systems Inc." - then an unknown 20-employee company in Menlo Park, California (USA). This is one of the first two Cisco boxes to appear in Switzerland, and possibly Europe. The 220v power supply was a special modification made for use at CERN. They supported IP address filtering, which seemed just what CERN needed to help protect the new Cray XMP-48 super computer from network hackers. The two ASM boxes were both routers and terminal servers. They protected a secure private Ethernet segment used by the Cray project, as well as providing secure terminal connections to that segment, including CERN's first dialback terminal service, which allowed Cray and CERN system analysts to work on the machine from home, using another Cisco feature called TACACS. (Kindly offered by B. Segal who discovered this company while at a Usenix Conference in Phoenix, Arizona in June 1987.)

  6. The metro area of Montreal.

    Science.gov (United States)

    1986-10-01

    Montreal, one of the most civilized and cosmopolitan of North American cities, is the 2nd city in Canada in size and the largest French-speaking city. Of the 2.8 million people who lived there at census time in 1981, 45% chose both French and English as their official language, 41% chose French, and 1% used some other language. Fully 68% of Montreal residents said their mother tongue was French, and 68% also said they spoke French at home. The importance of bilingualism to the business culture of Montreal cannot be overemphasized. In the last decade, French-Canadians have taken an increasingly stronger role in business. Upper-middle-class suburbs that as little as 10 years ago had only 10% of their residents who were of French-Canadian descent now have as many as 50-60% of their residents who are French-Canadians. Most residents of Montreal willingly learn 2 languages. US firms should assume that all representatives who are sent to Montreal should be fluent in both French and English. Montreal's 2,828,349 people create a population density of 1004.9 persons per square kilometer. Montreal has 665 census tracts, which are described in the Metropolitan Atlas Series. Nearly 62% of Montreal's population fall between the ages of 20 and 64--the prime working ages. Although Montreal is 79% Catholic, it does not have the high fertility levels often associated with Catholic areas. There were 1,026,920 households in Montreal in 1981 with an average of 2.7 persons per household. 71% of these were census family households. Montreal had 1,026,895 occupied dwellings in 1985 with an average of 5 rooms each. About 71% of the population aged 15 and over that were not in school were in the labor force; 41% of the labor force was female. The largest employment category for men was manufacturing (16%) and the largest for women was clerical work (39%).

  7. ASME Code Efforts Supporting HTGRs

    Energy Technology Data Exchange (ETDEWEB)

    D.K. Morton

    2010-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

  8. ASME Code Efforts Supporting HTGRs

    Energy Technology Data Exchange (ETDEWEB)

    D.K. Morton

    2011-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

  9. ASME Code Efforts Supporting HTGRs

    Energy Technology Data Exchange (ETDEWEB)

    D.K. Morton

    2012-09-01

    In 1999, an international collaborative initiative for the development of advanced (Generation IV) reactors was started. The idea behind this effort was to bring nuclear energy closer to the needs of sustainability, to increase proliferation resistance, and to support concepts able to produce energy (both electricity and process heat) at competitive costs. The U.S. Department of Energy has supported this effort by pursuing the development of the Next Generation Nuclear Plant, a high temperature gas-cooled reactor. This support has included research and development of pertinent data, initial regulatory discussions, and engineering support of various codes and standards development. This report discusses the various applicable American Society of Mechanical Engineers (ASME) codes and standards that are being developed to support these high temperature gascooled reactors during construction and operation. ASME is aggressively pursuing these codes and standards to support an international effort to build the next generation of advanced reactors so that all can benefit.

  10. Montreal Modern: Retro Culture and the Modern Past in Montreal

    Directory of Open Access Journals (Sweden)

    Kristian Handberg

    2015-03-01

    Full Text Available Through analyses of the retro scenes in Montreal, Canada, the article discusses retro culture's role as cultural memory. It is shown how Montreal's cultural identity is formed by memories of modern culture such as the Red-light and Sin City reputation of the illicit nightlife of the 1940s and 1950s, and the space age modernism of the 1960s following the Expo 67 and Quebec's Quiet Revolution. This is reflected in the city's thriving retro culture through the study of two groups of retro shops. In circulating specific memories and objects in a specific context, retro is an important negotiation of the past in the present. Especially, it is stated that the retro culture displays "local accents" and a new focus on the specificities of modern culture giving a revaluation to a previously overlooked identity such as the Quebecit.

  11. 77 FR 3073 - American Society of Mechanical Engineers (ASME) Codes and New and Revised ASME Code Cases...

    Science.gov (United States)

    2012-01-23

    ...-AI35 American Society of Mechanical Engineers (ASME) Codes and New and Revised ASME Code Cases... addenda to the ASME Boiler and Pressure Vessel (B&PV) Code, and the ASME Code for Operation and... on their use) ASME B&PV Code Cases N-722-1 and N-770-1. This document is necessary to correct...

  12. Globalization of ASME Nuclear Codes and Standards

    International Nuclear Information System (INIS)

    Swayne, Rick; Erler, Bryan A.

    2006-01-01

    With the globalization of the nuclear industry, it is clear that the reactor suppliers are based in many countries around the world (such as United States, France, Japan, Canada, South Korea, South Africa) and they will be marketing their reactors to many countries around the world (such as US, China, South Korea, France, Canada, Finland, Taiwan). They will also be fabricating their components in many different countries around the world. With this situation, it is clear that the requirements of ASME Nuclear Codes and Standards need to be adjusted to accommodate the regulations, fabricating processes, and technology of various countries around the world. It is also very important for the American Society of Mechanical Engineers (ASME) to be able to assure that products meeting the applicable ASME Code requirements will provide the same level of safety and quality assurance as those products currently fabricated under the ASME accreditation process. To do this, many countries are in the process of establishing or changing their regulations, and it is important for ASME to interface with the appropriate organizations in those countries, in order to ensure there is effective use of ASME Codes and standards around the world. (authors)

  13. ASME Material Challenges for Advanced Reactor Concepts

    Energy Technology Data Exchange (ETDEWEB)

    Piyush Sabharwall; Ali Siahpush

    2013-07-01

    This study presents the material Challenges associated with Advanced Reactor Concept (ARC) such as the Advanced High Temperature Reactor (AHTR). ACR are the next generation concepts focusing on power production and providing thermal energy for industrial applications. The efficient transfer of energy for industrial applications depends on the ability to incorporate cost-effective heat exchangers between the nuclear heat transport system and industrial process heat transport system. The heat exchanger required for AHTR is subjected to a unique set of conditions that bring with them several design challenges not encountered in standard heat exchangers. The corrosive molten salts, especially at higher temperatures, require materials throughout the system to avoid corrosion, and adverse high-temperature effects such as creep. Given the very high steam generator pressure of the supercritical steam cycle, it is anticipated that water tube and molten salt shell steam generators heat exchanger will be used. In this paper, the ASME Section III and the American Society of Mechanical Engineers (ASME) Section VIII requirements (acceptance criteria) are discussed. Also, the ASME material acceptance criteria (ASME Section II, Part D) for high temperature environment are presented. Finally, lack of ASME acceptance criteria for thermal design and analysis are discussed.

  14. International Accreditation of ASME Codes and Standards

    International Nuclear Information System (INIS)

    Green, Mervin R.

    1989-01-01

    ASME established a Boiler Code Committee to develop rules for the design, fabrication and inspection of boilers. This year we recognize 75 years of that Code and will publish a history of that 75 years. The first Code and subsequent editions provided for a Code Symbol Stamp or mark which could be affixed by a manufacturer to a newly constructed product to certify that the manufacturer had designed, fabricated and had inspected it in accordance with Code requirements. The purpose of the ASME Mark is to identify those boilers that meet ASME Boiler and Pressure Vessel Code requirements. Through thousands of updates over the years, the Code has been revised to reflect technological advances and changing safety needs. Its scope has been broadened from boilers to include pressure vessels, nuclear components and systems. Proposed revisions to the Code are published for public review and comment four times per year and revisions and interpretations are published annually; it's a living and constantly evolving Code. You and your organizations are a vital part of the feedback system that keeps the Code alive. Because of this dynamic Code, we no longer have columns in newspapers listing boiler explosions. Nevertheless, it has been argued recently that ASME should go further in internationalizing its Code. Specifically, representatives of several countries, have suggested that ASME delegate to them responsibility for Code implementation within their national boundaries. The question is, thus, posed: Has the time come to franchise responsibility for administration of ASME's Code accreditation programs to foreign entities or, perhaps, 'institutes.' And if so, how should this be accomplished?

  15. Improvement of ASME NH for Grade 91

    Energy Technology Data Exchange (ETDEWEB)

    Bernard Riou

    2007-10-09

    This report has been prepared in the context of Task 3 of the ASME/DOE Gen IV material project. It has been identified that creep-fatigue evaluation procedures presently available in ASME (1) and RCC-MR (2) have been mainly developed for austenitic stainless steels and may not be suitable for cyclic softening materials such as mod 9 Cr 1 Mo steel (grade 91). The aim of this document is, starting from experimental test results, to perform a review of the procedures and, if necessary, provide recommendations for their improvements.

  16. ASME Based Quality Documentation Guidelines for Power- and Recovery Boilers

    OpenAIRE

    Lappalainen, Tuomas

    2015-01-01

    The goal of this thesis was to create ASME-based quality documentation guidelines for power- and recovery boilers. The client was a large international power- and recovery boiler manufacturer. The content of this thesis is mainly a report of ASME code and its effects on quality documentation. In thesis are widely compared ASME based quality documention differences between PED/EN projects quality documentation. Also ASMEs most important elements for power- and recovery boiler projects needs fo...

  17. Activated sludge model No. 2d, ASM2d

    DEFF Research Database (Denmark)

    Henze, M.

    1999-01-01

    The Activated Sludge Model No. 2d (ASM2d) presents a model for biological phosphorus removal with simultaneous nitrification-denitrification in activated sludge systems. ASM2d is based on ASM2 and is expanded to include the denitrifying activity of the phosphorus accumulating organisms (PAOs......). This extension of ASM2 allows for improved modeling of the processes, especially with respect to the dynamics of nitrate and phosphate. (C) 1999 IAWQ Published by Elsevier Science Ltd. All rights reserved....

  18. 78 FR 37848 - ASME Code Cases Not Approved for Use

    Science.gov (United States)

    2013-06-24

    ... COMMISSION ASME Code Cases Not Approved for Use AGENCY: Nuclear Regulatory Commission. ACTION: Draft... public comment draft regulatory guide (DG), DG-1233, ``ASME Code Cases not Approved for Use.'' This regulatory guide lists the American Society of Mechanical Engineers (ASME) Code Cases that the NRC has...

  19. 1959 : Borden bails on Montreal question

    International Nuclear Information System (INIS)

    Anon.

    2008-01-01

    In 1959, following months of hearings, the Borden Royal Commission on Oil and Gas was unwilling to grant western producers the access to the Montreal refinery market. Rather than building a pipeline to Montreal, the Commission urged a national policy supporting the export of Canadian crude without license, and encouraging the use of Canadian crude in markets that already have pipeline access to it, including the west coast, Midwest and Ontario. The Commission recommended that the Canadian oil and gas industry take measures to enlarge its share of the United States market and asked that petroleum product retailers displace 50,000 barrels per day of products refined from imported crude in Montreal and sold in Ontario with a similar volume of products refined from Canadian crude. Proponents of the Commission's report stated that exports to the United States were essential to the Canadian oil industry and that a crude oil line to Montreal was not economic. Other key events in 1959 were listed in this article. Alberta and Southern sought approval to export 460 million cubic feet of gas per day to California. Dome Petroleum Limited suggested that the Arctic Islands could hold reserves of up to 100 billion barrels, and a planned nuclear explosion to free oil from the Athabasca oil sands was called off by the federal government for political reasons. 1 tab., 1 fig

  20. Proceedings: 2000 ASME/EPRI Radwaste Workshop

    International Nuclear Information System (INIS)

    2001-01-01

    Nuclear utilities are continually evaluating methods to improve operations and reduce costs associated with radioactive waste management. The continuing deregulation process has added increased emphasis to this activity. The Annual ASME/EPRI Workshop facilitates this effort by communicating technological and managerial improvements throughout the industry. This workshop, restricted to utility radwaste professionals, also serves to communicate practical in-plant improvements with the opportunity to discuss them in detail

  1. Proceedings: 2001 ASME/EPRI Radwaste Workshop

    International Nuclear Information System (INIS)

    2001-01-01

    Nuclear utilities continually evaluate methods to improve operations and reduce costs associated with radioactive waste management. The continuing deregulation process has increased the emphasis on this activity. The Annual ASME/EPRI Workshop facilitates this effort by communicating technology and management improvements throughout the industry. This workshop, restricted to utility radwaste professionals, also serves to communicate practical in-plant improvements with the opportunity to discuss them in detail

  2. [Ethnic entrepreneurship in Montreal: some preliminary results].

    Science.gov (United States)

    Juteau, D; Daviau-guay, J; Moallem, M

    1992-01-01

    "This research note presents a first sketch of a study we are undertaking on ethnic entrepreneurship [in Montreal]. It details first of all our theoretical framework and then presents some preliminary results. For this research, we are studying various ethnic groups, those in the majority as well as the minority. For each of them, we will analyze the impact that immigration status, sex, the industrial sector and urban context play on entrepreneurial activity." (SUMMARY IN ENG AND SPA) excerpt

  3. Temporal Deductive Verification of Basic ASM Models

    OpenAIRE

    Daho, Hocine El-Habib; University of Oran; Benhamamouch, Djillali; University of Oran

    2010-01-01

    Abstract State Machines (ASMs, for short) provide a practical new computational model which has been applied in the area of software engineering for systems design and analysis. However, reasoning about ASM models occurs, not within a formal deductive system, but basically in the classical informal proofs style of mathematics. Several formal verification approaches for proving correctness of ASM models have been investigated. In this paper we consider the use of the TLA+logic for the deductive...

  4. Chapter Seventeen

    African Journals Online (AJOL)

    User

    In the Perspectives of Language and Literature: Essays in Honour of R.U. Uzoezie. Chapter Seventeen ... knowledge, skills and values necessary for a person to become an effective agent of change are provided through .... It was in appreciation of this fact that the European Trade Union Committee for. Education (ETUCE) ...

  5. AsmL Specification of a Ptolemy II Scheduler

    DEFF Research Database (Denmark)

    Lázaro Cuadrado, Daniel; Koch, Peter; Ravn, Anders Peter

    2003-01-01

    Ptolemy II is a tool that combines different computational models for simulation and design of embedded systems. AsmL is a software specification language based on the Abstract State Machine formalism. This paper reports on development of an AsmL model of the Synchronous Dataflow domain scheduler...

  6. FY16 ASME High Temperature Code Activities

    Energy Technology Data Exchange (ETDEWEB)

    Swindeman, M. J. [Chromtech Inc., Oak Ridge, TN (United States); Jetter, R. I. [R. I Jetter Consulting, Pebble Beach, CA (United States); Sham, T. -L. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2016-09-01

    One of the objectives of the ASME high temperature Code activities is to develop and validate both improvements and the basic features of Section III, Division 5, Subsection HB, Subpart B (HBB). The overall scope of this task is to develop a computer program to be used to assess whether or not a specific component under specified loading conditions will satisfy the elevated temperature design requirements for Class A components in Section III, Division 5, Subsection HB, Subpart B (HBB). There are many features and alternative paths of varying complexity in HBB. The initial focus of this task is a basic path through the various options for a single reference material, 316H stainless steel. However, the program will be structured for eventual incorporation all the features and permitted materials of HBB. Since this task has recently been initiated, this report focuses on the description of the initial path forward and an overall description of the approach to computer program development.

  7. The Montreal Protocol for Identification of Amusia.

    Science.gov (United States)

    Vuvan, D T; Paquette, S; Mignault Goulet, G; Royal, I; Felezeu, M; Peretz, I

    2018-04-01

    The Montreal Battery for the Evaluation of Amusia (MBEA; Peretz, Champod, & Hyde Annals of the New York Academy of Sciences, 999, 58-75, 2003) is an empirically grounded quantitative tool that is widely used to identify individuals with congenital amusia. The use of such a standardized measure ensures that the individuals tested will conform to a specific neuropsychological profile, allowing for comparisons across studies and research groups. Recently, a number of researchers have published credible critiques of the usefulness of the MBEA as a diagnostic tool for amusia. Here we argue that the MBEA and its online counterpart, the AMUSIA tests (Peretz et al. Music Perception, 25, 331-343, 2008), should be considered steps in a screening process for amusia, rather than standalone diagnostic tools. The goal of this article is to present, in detailed and easily replicable format, the full protocol through which congenital amusics should be identified. In providing information that has often gone unreported in published articles, we aim to clarify the strengths and limitations of the MBEA and to make recommendations for its continued use by the research community as part of the Montreal Protocol for Identification of Amusia.

  8. Chapter 3

    International Nuclear Information System (INIS)

    Brin, Andre.

    1979-01-01

    Various aspects of the relationship between nuclear energy and the sea are examined in this chapter since, at this moment in time, the sea appears to be a source of cooling water for nuclear power stations; nuclear propulsion has upset a certain number of data on naval forces and the uranium ressources in the water of the seas are sometimes mentioned. But the sea could also become the depository for radioactive waste. Therefore care must be taken to preserve the quality of the marine environment by preventing sizeable amounts of radioactive matter from contaminating it [fr

  9. Accelerator System Model (ASM) user manual with physics and engineering model documentation. ASM version 1.0

    International Nuclear Information System (INIS)

    1993-07-01

    The Accelerator System Model (ASM) is a computer program developed to model proton radiofrequency accelerators and to carry out system level trade studies. The ASM FORTRAN subroutines are incorporated into an intuitive graphical user interface which provides for the open-quotes constructionclose quotes of the accelerator in a window on the computer screen. The interface is based on the Shell for Particle Accelerator Related Codes (SPARC) software technology written for the Macintosh operating system in the C programming language. This User Manual describes the operation and use of the ASM application within the SPARC interface. The Appendix provides a detailed description of the physics and engineering models used in ASM. ASM Version 1.0 is joint project of G. H. Gillespie Associates, Inc. and the Accelerator Technology (AT) Division of the Los Alamos National Laboratory. Neither the ASM Version 1.0 software nor this ASM Documentation may be reproduced without the expressed written consent of both the Los Alamos National Laboratory and G. H. Gillespie Associates, Inc

  10. 1985 ASME-EPRI radwaste workshop: proceedings

    International Nuclear Information System (INIS)

    Coplan, B.V.

    1985-07-01

    The proceedings of the seventh ASME/EPRI jointly sponsored radwaste workshop are presented. The workshop presentations and discussion sessions addressed the following pertinent issues: Meeting Radwaste Regulatory Requirements; Mobile Services; and Radwaste Equipment and Reducing Costs. Interest in meeting regulatory requirements centered on the various aspects of 10CFR61. Proper sampling, compliance methodology, hydrogen generation in stored radwaste and process control programs were the major topics of discussion. Use of mobile services provided by outside organizations is increasing. An extensive summary of available mobile services was presented in the areas of radwaste processing, solidification and decontamination, as well as information on special on-site storage containers. Under the areas of radwaste equipment and reducing costs, the principal items were the status of a mobile incinerator for Commonwealth Edison, establishment of a deminimis level for waste at Ginna, resin volume reduction at Brunswick and a dry active waste segregation program at TVA. Presentations were also made on radwaste transportation and burial and on two planned regional radwaste incineration facilities. The meeting concluded with an open discussion period for all participants on a variety of radwaste items

  11. Auriculoterapia en pacientes asmáticos

    Directory of Open Access Journals (Sweden)

    Adolfo González Salvador

    1997-04-01

    Full Text Available Se realiza un estudio para evaluar la eficacia de la auriculopuntura en 30 asmáticos del área de salud de Aguada de Pasajeros, durante los meses de noviembre de 1992 a abril de 1993. El tratamiento se aplicó durante un mes, con seguimiento durante los 5 meses posteriores. Se observó una disminución en la frecuencia, intensidad y duración de las crisis de asma; la mayoría de los pacientes tuvo una evolución satisfactoria y no se presentaron complicaciones. Se concluye que la auriculoterapia es un método útil en pacientes con asma bronquial debido a su eficacia e inocuidadA study was conducted to evaluate the efficacy of auriculopuncture in 30 asthmatic patients from the health area of Aguada de Pasajeros between November, 1992, and April, 1993. The treatment was applied for a month, with a follow-up during the next 5 months. It was observed a reduction in the frequency, intensity and duration of the asthma crises. Most of the patients had a satisfactory evolution and there were no complications. It is concluded that auriculotherapy is a useful method for patients with bronchial asthma due to its effectiveness and innocuousness.

  12. An example of a component replacement when applying ASME N509 and ASME N510 to older ventilation systems

    Energy Technology Data Exchange (ETDEWEB)

    Arndt, T.E. [Westinghouse Hanford Company, Richland, WA (United States)

    1995-02-01

    This paper presents an example of a component replacement (electric heater) when installed in an older ventilation system that was constructed before the issuance of ASME N509{sup 1} and N510{sup 2}. Many of the existing ventilation systems at the Hanford Site were designed, fabricated, and installed before the issuance of ASME N509{sup 1} and N510{sup 2}. Requiring the application of these codes to existing ventilation systems presents challenges to the engineer when design changes are needed. Although it may seem that the application of ASME N509{sup 1} or N510{sup 2} may be a hindrance at times, this does not need to occur. Proper preparation at the start of project or design modifications can minimize frustration to the engineer when it is judged that portions of ASME N509{sup 1} and N510{sup 2} do not apply in a particular application.

  13. ASME nuclear codes and standards risk management strategic planning

    International Nuclear Information System (INIS)

    Hill, Ralph S. III; Balkey, Kenneth R.; Erler, Bryan A.; Wesley Rowley, C.

    2007-01-01

    This paper is prepared in honor and in memory of the late Professor Emeritus Yasuhide Asada to recognize his contributions to ASME Nuclear Codes and Standards initiatives, particularly those related to risk-informed technology and System Based Code developments. For nearly two decades, numerous risk-informed initiatives have been completed or are under development within the ASME Nuclear Codes and Standards organization. In order to properly manage the numerous initiatives currently underway or planned for the future, the ASME Board on Nuclear Codes and Standards (BNCS) has an established Risk Management Strategic Plan (Plan) that is maintained and updated by the ASME BNCS Risk Management Task Group. This paper presents the latest approved version of the plan beginning with a background of applications completed to date, including the recent probabilistic risk assessment (PRA) standards developments for nuclear power plant applications. The paper discusses planned applications within ASME Nuclear Codes and Standards that will require expansion of the ASME PRA Standard to support new advanced light water reactor and next generation reactor developments, such as for high temperature gas-cooled reactors. Emerging regulatory developments related to risk-informed, performance- based approaches are summarized. A long-term vision for the potential development and evolution to a nuclear systems code that adopts a risk-informed approach across a facility life-cycle (design, construction, operation, maintenance, and closure) is also summarized. Finally, near term and long term actions are defined across the ASME Nuclear Codes and Standards organizations related to risk management, including related U.S. regulatory activities. (author)

  14. Comparison between ASME and ISO standards on surface texture

    Science.gov (United States)

    Hu, Kai; Jiang, Xiangqian; Liu, Xiaojun; Xu, Zhengao

    2006-11-01

    Surface texture is generally a significant technique requirement of high-tech products. Surface quality information can usually play an increasing role in achieving interoperability among existing products, create order in markets, simplify production and ensure safety. As the most authoritative standard organizations, ASME and ISO services are used throughout the world, their codes and standards influence global manufacturers and consumers. ASME B46.1 is one of many vital tools to promote surface measurement techniques, while ISO has a set standard system for surface measurement, analysis and evaluation. This paper compares the ASME B46.1 (2002) standard (Surface texture: surface roughness, waviness, and lay) with ISO 3274 (1997) standard on methods of surface profiles filtering. It preformed the present research in order to show the latest developments of the ASME B46.1 (2002) in the regime of contact profiling techniques where the degree of measurement control is highly advanced, and a large range of other techniques that present valid and useful descriptions of surface texture. Also, this paper shows the differences of terms, definitions and surface texture parameters between ASME B46.1 (2002) and ISO 4287 (1998). The different evaluation results have been calculated based on above two standards for the same surface data. Obviously, it is necessary to consider the divergence above to develop China's standards (GB) on surface texture.

  15. Penetration of ASM 981 in canine skin: a comparative study.

    Science.gov (United States)

    Gutzwiller, Meret E Ricklin; Reist, Martin; Persohn, Elke; Peel, John E; Roosje, Petra J

    2006-01-01

    ASM 981 has been developed for topical treatment of inflammatory skin diseases. It specifically inhibits the production and release of pro-inflammatory cytokines. We measured the skin penetration of ASM 981 in canine skin and compared penetration in living and frozen skin. To make penetration of ASM 981 visible in dog skin, tritium labelled ASM 981 was applied to a living dog and to defrosted skin of the same dog. Using qualitative autoradiography the radioactive molecules were detected in the lumen of the hair follicles until the infundibulum, around the superficial parts of the hair follicles and into a depth of the dermis of 200 to 500 microm. Activity could not be found in deeper parts of the hair follicles, the dermis or in the sebaceous glands. Penetration of ASM 981 is low in canine skin and is only equally spread in the upper third of the dermis 24 hours after application. Penetration in frozen skin takes even longer than in living canine skin but shows the same distribution.

  16. Index to place of publication of ASME Papers, 1978--1988

    International Nuclear Information System (INIS)

    Youngen, G.K.

    1990-06-01

    This index is a list of American Society of Mechanical Engineers (ASME) Papers that are reprinted in the ASME Transactions series of journals. ASME Papers are often cited only by their paper number, making it difficult to determine if the article has ever appeared in print in the journal literature. This index will be useful for tracking down those papers published as journal articles by the ASME. It will also serve as a guide for retention for subscribers to the ASME Papers and Transaction Series. Paper numbers that appear in the journals may be weeded from the collection of ASME Papers

  17. Inservice inspection procedures and training according to the ASME code

    International Nuclear Information System (INIS)

    Greenwald, S.M.; Chockie, L.J.

    1987-01-01

    Mandatory training of the technical staff at a nuclear power plant is of paramount importance if we are to avoid costly plant shutdowns. This training should include the requirements for both Preservice and Inservice Inspection, in addition to Quality Assurance procedures as required by the American Society of Mechanical Engineers (ASME) Code. The training is best accomplished by utilizing instructors who are thoroughly familiar with plant operations and the ASME Code, as well as serving on one of the Code committees. This paper focuses on the Inservice Inspection procedures and the results of an intensive training effort to implement such procedures. (author)

  18. Inservice inspection procedures and training according to the ASME code

    Energy Technology Data Exchange (ETDEWEB)

    Greenwald, S.M.; Chockie, L.J.

    1988-01-01

    Mandatory training of the technical staff at a nuclear power plant is of paramount importance if we are to avoid costly plant shutdowns. This training should include the requirements for both Preservice and inservice Inspection, in addition to Quality Assurance procedures as required by the American Society of Mechanical Engineers (ASME) Code. The training is best accomplished by utilizing instructors who are thoroughly familiar with plant operations and the ASME Code, as well as serving on one of the code committees. This paper focuses on the Inservice Inspection procedures and the results of an intensive training effort to implement such procedures.

  19. AsmL Specification of a Ptolemy II Scheduler

    DEFF Research Database (Denmark)

    Lázaro Cuadrado, Daniel; Koch, Peter; Ravn, Anders Peter

    2003-01-01

    Ptolemy II is a tool that combines different computational models for simulation and design of embedded systems. AsmL is a software specification language based on the Abstract State Machine formalism. This paper reports on development of an AsmL model of the Synchronous Dataflow domain scheduler...... of Ptolemy II. By building this model we can give precise semantics to the implementation. Furthermore it allows us to isolate the scheduling problem from the tool and make the potential parallelism of the implementation explicit. The model is executable and is tested against the implementation...

  20. The human ASM (adult skeletal muscle) gene: expression and chromosomal assignment to 11p15.

    Science.gov (United States)

    Leibovitch, M P; Nguyen, V C; Gross, M S; Solhonne, B; Leibovitch, S A; Bernheim, A

    1991-11-14

    A rat adult skeletal muscle probe (Asm15) originated from a rhabdomyosarcoma was used to isolate the human homologous sequence from a placenta cDNA library. Among several positive clones the longest EcoRI-EcoRI insert (ASM1) obtained was 1875 bp long with 72% homology with rat Asm15 cDNA sequence. Important variations of ASM1 RNA level were observed in different adult skeletal muscles. Expression of a 29kD ASM1 protein was demonstrated in human adult skeletal muscle lysates using an antiserum (PB1579) raised against the C terminal region of the rat Asm15 protein. The human ASM gene was assigned by somatic cell analysis with human (ASM1) and rat (Asm15) probes to chromosome 11, and by in situ hybridization with the human probe to 11p15, a chromosome region involved in human embryonal rhabdomyosarcomas. Except for the presence of a HindII restriction site, the results obtained for the restriction map and the sequence of ASM1 cDNA (data not shown) exhibited extensive homology with the human H19 DNA sequence which have been mapped with a mouse probe also in 11p15. This suggests that ASM/Asm and H19 may represent the same sequence (in this hypothesis the presence of the supplementary HindII site in our ASM1 probe is explained by polymorphic variability). However it was reported that human and mouse H19 mRNA did not encode for a protein but acted as an RNA molecule whereas in our present study ASM protein was detected in human adult skeletal muscle. This could be explained by important regulation of ASM protein expression during development and cell differentiation. However we cannot exclude for the different species studied (mouse, rat, and man) the hypothesis that H19 and ASM/Asm mRNA may represent two distinct messengers from the same gene or even from duplicated genes.

  1. 14 CFR 330.31 - What data must air carriers submit concerning ASMs or RTMs?

    Science.gov (United States)

    2010-01-01

    ... combination passenger/cargo carrier, you must have submitted your August 2001 total completed ASM report to... correct an error that you document to the Department, you must not alter the ASM or RTM reports you...

  2. The importance of the Montreal Protocol in protecting climate.

    Science.gov (United States)

    Velders, Guus J M; Andersen, Stephen O; Daniel, John S; Fahey, David W; McFarland, Mack

    2007-03-20

    The 1987 Montreal Protocol on Substances that Deplete the Ozone Layer is a landmark agreement that has successfully reduced the global production, consumption, and emissions of ozone-depleting substances (ODSs). ODSs are also greenhouse gases that contribute to the radiative forcing of climate change. Using historical ODSs emissions and scenarios of potential emissions, we show that the ODS contribution to radiative forcing most likely would have been much larger if the ODS link to stratospheric ozone depletion had not been recognized in 1974 and followed by a series of regulations. The climate protection already achieved by the Montreal Protocol alone is far larger than the reduction target of the first commitment period of the Kyoto Protocol. Additional climate benefits that are significant compared with the Kyoto Protocol reduction target could be achieved by actions under the Montreal Protocol, by managing the emissions of substitute fluorocarbon gases and/or implementing alternative gases with lower global warming potentials.

  3. Los mexicanos en Montreal: ¿Una comunidad transnacional?

    Directory of Open Access Journals (Sweden)

    Juan Luis Klein

    2017-01-01

    Full Text Available Este artículo analiza los lazos que los inmigrantes mexicanos en Montreal man- tienen con la sociedad de acogida y con sus comunidades de origen. Nos basamos en el estudio de documentos y en la realización de entrevistas con empresarios, profesionales y refugiados mexicanos residentes en Montreal. Concluimos que los mexicanos residentes en Montreal viven su identidad territorial en una situa- ción de tensión social y económica donde domina un sentimiento de pertenen- cia híbrida. “No nos sentimos ni de aquí, ni de allá” nos confía la mayoría de los entrevistados, lo cual da muestras de una comunidad transnacional en gestación.

  4. Asm-1(+), a Neurospora Crassa Gene Related to Transcriptional Regulators of Fungal Development

    OpenAIRE

    Aramayo, R.; Peleg, Y.; Addison, R.; Metzenberg, R.

    1996-01-01

    This report describes the identification, cloning, and molecular analysis of Asm-1(+) (Ascospore maturation 1), the Neurospora crassa homologue of the Aspergillus nidulans stuA (stunted A) gene. The Asm-1(+) gene is constitutively transcribed and encodes an abundant, nucleus-localized 68.5-kD protein. The protein product of Asm-1(+) (ASM-1), contains a potential DNA-binding motif present in related proteins from A. nidulans (StuA), Candida albicans (EFGTF-1), and Saccharomyces cerevisiae (Phd...

  5. Abelian Sandpile Model (ASM) and Infinite Volume Limit

    Indian Academy of Sciences (India)

    Self Organised Criticality (SOC). SOC- dynamics drive a system towards stationary state characterized by power law correlations in space and time. SOC- was proposed by [BTW 87,88] as a mechanism which could explain occurrence of fractal structures in diverse natural phenomena. ASM is a simple model where SOC ...

  6. Adaptation illustrations: Chapter 4

    Science.gov (United States)

    Maria Janowiak; Patricia Butler; Chris Swanston; Matt St. Pierre; Linda. Parker

    2012-01-01

    In this chapter, we demonstrate how the Adaptation Workbook (Chapter 3) can be used with the Adaptation Strategies and Approaches (Chapter 2) to develop adaptation tactics for two real-world management issues. The two illustrations in this chapter are intended to provide helpful tips to managers completing the Adaptation Workbook, as well as to show how the anticipated...

  7. 46 CFR 57.02-2 - Adoption of section IX of the ASME Code.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Adoption of section IX of the ASME Code. 57.02-2 Section... AND BRAZING General Requirements § 57.02-2 Adoption of section IX of the ASME Code. (a) The... accordance with section IX of the ASME (American Society of Mechanical Engineers) Code, as limited, modified...

  8. Selections from the ABC 2011 Annual Convention, Montreal, Canada

    Science.gov (United States)

    Whalen, D. Joel; Andersen, Ken; Campbell, Gloria; Crenshaw, Cheri; Cross, Geoffrey A.; Grinols, Anne Bradstreet; Hildebrand, John; Newman, Amy; Ortiz, Lorelei A.; Paulson, Edward; Phillabaum, Melinda; Powell, Elizabeth A.; Sloan, Ryan

    2012-01-01

    The 12 Favorite Assignments featured in this article were presented at the 2011 Annual Convention of the Association for Business Communication (ABC), Montreal, Canada. A variety of learning objectives are featured: delivering bad news, handling difficult people, persuasion, reporting financial analysis, electronic media, face-to-face…

  9. Mini‑Mental State Exam versus Montreal Cognitive Assessment in ...

    African Journals Online (AJOL)

    Background: Mini‑mental state exam (MMSE) was used several times but no study has examined cognition on the Montreal Cognitive Assessment (MoCA) in diabetes and diabetic retinopathy (DR). In this study, we compared MMSE with MoCA in patients with DR and searched for an association between the severity of DR ...

  10. The importance of the Montreal Protocol in protecting climate

    NARCIS (Netherlands)

    Velders, G.J.M.; Andersen, S.O.; Daniel, J.S.; Fahey, D.W.; McFarland, M.

    2007-01-01

    The 1987 Montreal Protocol on Substances that Deplete the Ozone Layer is a landmark agreement that has successfully reduced the global production, consumption, and emissions of ozone-depleting substances (ODSs). ODSs are also greenhouse gases that contribute to the radiative forcing of climate

  11. Montreal Declaration People\\'s Right to Safety | Conference Report ...

    African Journals Online (AJOL)

    6th World Conference on Injury Prevention and Control, Montreal, Canada, 15th May 2002. African Safety Promotion Vol.1(1) 2002: 78-81. AJOL African Journals Online. HOW TO USE AJOL... for Researchers · for Librarians · for Authors · FAQ's · More about AJOL · AJOL's Partners · Terms and Conditions of Use · Contact ...

  12. Bibliometric Analyses Reveal Patterns of Collaboration between ASMS Members

    Science.gov (United States)

    Palmblad, Magnus; van Eck, Nees Jan

    2018-01-01

    We have explored the collaborative network of the current American Society for Mass Spectrometry (ASMS) membership using bibliometric methods. The analysis shows that 4249 members are connected in a single, large, co-authorship graph, including the majority of the most published authors in the field of mass spectrometry. The map reveals topographical differences between university groups and national laboratories, and that the co-authors with the strongest links have long worked together at the same location. We have collected and summarized information on the geographical distribution of members, showing a high coverage of active researchers in North America and Western Europe. Looking at research fields, we could also identify a number of new or `hot' topics among ASMS members. Interactive versions of the maps are available on-line at https://goo.gl/UBNFMQ (collaborative network) and https://goo.gl/WV25vm (research topics).

  13. Bibliometric Analyses Reveal Patterns of Collaboration between ASMS Members.

    Science.gov (United States)

    Palmblad, Magnus; van Eck, Nees Jan

    2018-03-01

    We have explored the collaborative network of the current American Society for Mass Spectrometry (ASMS) membership using bibliometric methods. The analysis shows that 4249 members are connected in a single, large, co-authorship graph, including the majority of the most published authors in the field of mass spectrometry. The map reveals topographical differences between university groups and national laboratories, and that the co-authors with the strongest links have long worked together at the same location. We have collected and summarized information on the geographical distribution of members, showing a high coverage of active researchers in North America and Western Europe. Looking at research fields, we could also identify a number of new or 'hot' topics among ASMS members. Interactive versions of the maps are available on-line at https://goo.gl/UBNFMQ (collaborative network) and https://goo.gl/WV25vm (research topics). Graphical Abstract ᅟ.

  14. Bibliometric Analyses Reveal Patterns of Collaboration between ASMS Members

    Science.gov (United States)

    Palmblad, Magnus; van Eck, Nees Jan

    2018-03-01

    We have explored the collaborative network of the current American Society for Mass Spectrometry (ASMS) membership using bibliometric methods. The analysis shows that 4249 members are connected in a single, large, co-authorship graph, including the majority of the most published authors in the field of mass spectrometry. The map reveals topographical differences between university groups and national laboratories, and that the co-authors with the strongest links have long worked together at the same location. We have collected and summarized information on the geographical distribution of members, showing a high coverage of active researchers in North America and Western Europe. Looking at research fields, we could also identify a number of new or `hot' topics among ASMS members. Interactive versions of the maps are available on-line at https://goo.gl/UBNFMQ (collaborative network) and https://goo.gl/WV25vm (research topics). [Figure not available: see fulltext.

  15. Investigating ASME allowable loads with finite element analyses

    International Nuclear Information System (INIS)

    Mattar Neto, Miguel; Bezerra, Luciano M.; Miranda, Carlos A. de J.; Cruz, Julio R.B.

    1995-01-01

    The evaluation of nuclear components using finite element analysis (FEA) does not generally fall into the shell type verification adopted by the ASME Code. Consequently, the demonstration that the modes of failure are avoided sometimes is not straightforward. Allowable limits, developed by limit load theory, require the computation of shell membrane and bending stresses. How to calculate these stresses from FEA is not necessarily self-evident. One approach to be considered is to develop recommendations in a case-by-case basis for the most common pressure vessel geometries and loads based on comparison between the results of elastic and plastic FEA. In this paper, FE analyses of common 2D and complex 3D geometries are examined and discussed. It will be clear that in the cases studied, stress separation and categorization are not self-evident and simple tasks to undertake. Certain unclear recommendations of ASME Code can lead the stress analyst to non conservative designs as will be demonstrated in this paper. At the endo of this paper, taking into account comparison between elastic and elastic-plastic FE results from ANSYS some observations, suggestions and conclusions about the degree of conservatism of the ASME recommendations will be addressed. (author)

  16. Design Procedure of Graphite Components by ASME HTR Codes

    Energy Technology Data Exchange (ETDEWEB)

    Kang, Ji-Ho; Jo, Chang Keun [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    In this study, the ASME B and PV Code, Subsection HH, Subpart A, design procedure for graphite components of HTRs was reviewed and the differences from metal materials were remarked. The Korean VHTR has a prismatic core which is made of multiple graphite blocks, reflectors, and core supports. One of the design issues is the assessment of the structural integrity of the graphite components because the graphite is brittle and shows quite different behaviors from metals in high temperature environment. The American Society of Mechanical Engineers (ASME) issued the latest edition of the code for the high temperature reactors (HTR) in 2015. In this study, the ASME B and PV Code, Subsection HH, Subpart A, Graphite Materials was reviewed and the special features were remarked. Due the brittleness of graphites, the damage-tolerant design procedures different from the conventional metals were adopted based on semi-probabilistic approaches. The unique additional classification, SRC, is allotted to the graphite components and the full 3-D FEM or equivalent stress analysis method is required. In specific conditions, the oxidation and viscoelasticity analysis of material are required. The fatigue damage rule has not been established yet.

  17. Rethinking ASME III seismic analysis for piping operability evaluations

    International Nuclear Information System (INIS)

    Adams, T.M.; Stevenson, J.D.

    1994-01-01

    It has been recognized since the mid 1980's that there are very large seismic margins to failure for nuclear piping systems when designed using current industry practice, design criteria, and methods. As a result of this realization there are or have been approximately eighteen initiatives within the ASME , Boiler and Pressure Vessel Code Section III, Division 1, in the form of proposed code cases and proposed code text changes designed to reduce these failure margins to more realistic values. For the most part these initiatives have concentrated on reclassifying seismic inertia stresses in the piping as secondary and increasing the allowable stress limits permitted by Section III of the ASME, Boiler Code. This paper focuses on the application of non-linear spectral analysis methods as a method to reduce the input seismic demand determination and thereby reduce the seismic failure margins. The approach is evaluated using the ASME Boiler Pressure Vessel Code Section III Subgroup on Design benchmark procedure as proposed by the Subgroup's Special Task Group on Integrated Piping Criteria. Using this procedure, criteria are compared to current code criterion and analysis methods, and several other of the currently proposed Boiler and Pressure Vessel, Section III, changes. Finally, the applicability of the non-linear spectral analysis to continued Safe Operation Evaluations is reviewed and discussed

  18. Chapter 10: Management recommendations

    Science.gov (United States)

    Deborah M. Finch; Janie Agyagos; Tracy McCarthey; Robert M. Marshall; Scott H. Stoleson; Mary J. Whitfield

    2000-01-01

    This chapter was developed over a series of meetings using a group-consensus process. Our recommendations are based on published results, on information compiled in the previous chapters, on expert opinion, and on unpublished data of conservation team members. This chapter is available as temporary guidance until the Recovery Plan for the southwestern willow flycatcher...

  19. The History of Surgery at the Montreal Heart Institute.

    Science.gov (United States)

    Grondin, Claude M; Cartier, Raymond; Roy, Denis; Perrault, Louis P

    2016-01-01

    The Montreal Heart Institute (MHI) is a specialty hospital dedicated to cardiology and heart surgery. Founded in 1954 by Paul David, it is currently affiliated with the Université de Montréal. The Montreal Heart Institute is a center that has rested on the shoulders of multiple pioneers over the past 63 years. Renowned for its sustained excellence and commitment to patient care, the MHI also focuses on research and innovation. It has become one of the leading heart institutions in modern cardiac surgery and also one of the busiest cardiac surgery centers in the country. Our leaders have impacted the treatment of patients with heart diseases through clinical care and education. Staff surgeons have been trained at top centers across the world for the benefit of Canadian patients. The MHI was a pioneer in heart transplantation and CABG surgery and focuses on evaluative research of new technology. Copyright © 2016. Published by Elsevier Inc.

  20. Tuberculosis and homelessness in Montreal: a retrospective cohort study.

    Science.gov (United States)

    Tan de Bibiana, Jason; Rossi, Carmine; Rivest, Paul; Zwerling, Alice; Thibert, Louise; McIntosh, Fiona; Behr, Marcel A; Menzies, Dick; Schwartzman, Kevin

    2011-10-28

    Montreal is Canada's second-largest city, where mean annual tuberculosis (TB) incidence from 1996 to 2007 was 8.9/100,000. The objectives of this study were to describe the epidemiology of TB among homeless persons in Montreal and assess patterns of transmission and sharing of key locations. We reviewed demographic, clinical, and microbiologic data for all active TB cases reported in Montreal from 1996 to 2007 and identified persons who were homeless in the year prior to TB diagnosis. We genotyped all available Mycobacterium tuberculosis isolates by IS6110 restriction fragment length polymorphism (IS6110-RFLP) and spoligotyping, and used a geographic information system to identify potential locations for transmission between persons with matching isolates. There were 20 cases of TB in homeless persons, out of 1823 total reported from 1996-2007. 17/20 were Canadian-born, including 5 Aboriginals. Homeless persons were more likely than non-homeless persons to have pulmonary TB (20/20), smear-positive disease (17/20, odds ratio (OR) = 5.7, 95% confidence interval (CI): 1.7-20), HIV co-infection (12/20, OR = 14, 95%CI: 4.8-40), and a history of substance use. The median duration from symptom onset to diagnosis was 61 days for homeless persons vs. 28 days for non-homeless persons (P = 0.022). Eleven homeless persons with TB belonged to genotype-defined clusters (OR = 5.4, 95%CI: 2.2-13), and ten potential locations for transmission were identified, including health care facilities, homeless shelters/drop-in centres, and an Aboriginal community centre. TB cases among homeless persons in Montreal raise concerns about delayed diagnosis and ongoing local transmission.

  1. Tuberculosis and homelessness in Montreal: a retrospective cohort study

    Directory of Open Access Journals (Sweden)

    Tan de Bibiana Jason

    2011-10-01

    Full Text Available Abstract Background Montreal is Canada's second-largest city, where mean annual tuberculosis (TB incidence from 1996 to 2007 was 8.9/100,000. The objectives of this study were to describe the epidemiology of TB among homeless persons in Montreal and assess patterns of transmission and sharing of key locations. Methods We reviewed demographic, clinical, and microbiologic data for all active TB cases reported in Montreal from 1996 to 2007 and identified persons who were homeless in the year prior to TB diagnosis. We genotyped all available Mycobacterium tuberculosis isolates by IS6110 restriction fragment length polymorphism (IS6110-RFLP and spoligotyping, and used a geographic information system to identify potential locations for transmission between persons with matching isolates. Results There were 20 cases of TB in homeless persons, out of 1823 total reported from 1996-2007. 17/20 were Canadian-born, including 5 Aboriginals. Homeless persons were more likely than non-homeless persons to have pulmonary TB (20/20, smear-positive disease (17/20, odds ratio (OR = 5.7, 95% confidence interval (CI: 1.7-20, HIV co-infection (12/20, OR = 14, 95%CI: 4.8-40, and a history of substance use. The median duration from symptom onset to diagnosis was 61 days for homeless persons vs. 28 days for non-homeless persons (P = 0.022. Eleven homeless persons with TB belonged to genotype-defined clusters (OR = 5.4, 95%CI: 2.2-13, and ten potential locations for transmission were identified, including health care facilities, homeless shelters/drop-in centres, and an Aboriginal community centre. Conclusions TB cases among homeless persons in Montreal raise concerns about delayed diagnosis and ongoing local transmission.

  2. Tuberculosis and homelessness in Montreal: a retrospective cohort study

    Science.gov (United States)

    2011-01-01

    Background Montreal is Canada's second-largest city, where mean annual tuberculosis (TB) incidence from 1996 to 2007 was 8.9/100,000. The objectives of this study were to describe the epidemiology of TB among homeless persons in Montreal and assess patterns of transmission and sharing of key locations. Methods We reviewed demographic, clinical, and microbiologic data for all active TB cases reported in Montreal from 1996 to 2007 and identified persons who were homeless in the year prior to TB diagnosis. We genotyped all available Mycobacterium tuberculosis isolates by IS6110 restriction fragment length polymorphism (IS6110-RFLP) and spoligotyping, and used a geographic information system to identify potential locations for transmission between persons with matching isolates. Results There were 20 cases of TB in homeless persons, out of 1823 total reported from 1996-2007. 17/20 were Canadian-born, including 5 Aboriginals. Homeless persons were more likely than non-homeless persons to have pulmonary TB (20/20), smear-positive disease (17/20, odds ratio (OR) = 5.7, 95% confidence interval (CI): 1.7-20), HIV co-infection (12/20, OR = 14, 95%CI: 4.8-40), and a history of substance use. The median duration from symptom onset to diagnosis was 61 days for homeless persons vs. 28 days for non-homeless persons (P = 0.022). Eleven homeless persons with TB belonged to genotype-defined clusters (OR = 5.4, 95%CI: 2.2-13), and ten potential locations for transmission were identified, including health care facilities, homeless shelters/drop-in centres, and an Aboriginal community centre. Conclusions TB cases among homeless persons in Montreal raise concerns about delayed diagnosis and ongoing local transmission. PMID:22034944

  3. Computer Program of SIE ASME-NH (Revision 1.0) Code

    Energy Technology Data Exchange (ETDEWEB)

    Koo, Gyeong Hoi; Lee, J. H

    2008-01-15

    In this report, the SIE ASME (Structural Integrity Evaluations by ASME-NH) (Revision 1.0), which has a computerized implementation of ASME Pressure Vessels and Piping Code Section III Subsection NH rules, is developed to apply to the next generation reactor design subjecting to the elevated temperature operations over 500 .deg. C and over 30 years design lifetime, and the user's manual for this program is described in detail.

  4. Computer Program of SIE ASME-NH (Revision 1.0) Code

    International Nuclear Information System (INIS)

    Koo, Gyeong Hoi; Lee, J. H.

    2008-01-01

    In this report, the SIE ASME (Structural Integrity Evaluations by ASME-NH) (Revision 1.0), which has a computerized implementation of ASME Pressure Vessels and Piping Code Section III Subsection NH rules, is developed to apply to the next generation reactor design subjecting to the elevated temperature operations over 500 .deg. C and over 30 years design lifetime, and the user's manual for this program is described in detail

  5. ASM-024, a piperazinium compound, promotes the in vitro relaxation of β2-adrenoreceptor desensitized tracheas.

    Science.gov (United States)

    Israël-Assayag, Evelyne; Beaulieu, Marie-Josée; Cormier, Yvon

    2015-01-01

    Inhaled β2-adrenoreceptor agonists are widely used in asthma and chronic obstructive pulmonary disease (COPD) for bronchoconstriction relief. β2-Adrenoreceptor agonists relax airway smooth muscle cells via cyclic adenosine monophosphate (cAMP) mediated pathways. However, prolonged stimulation induces functional desensitization of the β2-adrenoreceptors (β2-AR), potentially leading to reduced clinical efficacy with chronic or prolonged administration. ASM-024, a small synthetic molecule in clinical stage development, has shown activity at the level of nicotinic receptors and possibly at the muscarinic level and presents anti-inflammatory and bronchodilator properties. Aerosolized ASM-024 reduces airway resistance in mice and promotes in-vitro relaxation of tracheal and bronchial preparations from animal and human tissues. ASM-024 increased in vitro relaxation response to maximally effective concentration of short-acting beta-2 agonists in dog and human bronchi. Although the precise mechanisms by which ASM-024 promotes airway smooth muscle (ASM) relaxation remain unclear, we hypothesized that ASM-024 will attenuate and/or abrogate agonist-induced contraction and remain effective despite β2-AR tachyphylaxis. β2-AR tachyphylaxis was induced with salbutamol, salmeterol and formoterol on guinea pig tracheas. The addition of ASM-024 relaxed concentration-dependently intact or β2-AR desensitized tracheal rings precontracted with methacholine. ASM-024 did not induce any elevation of intracellular cAMP in isolated smooth muscle cells; moreover, blockade of the cAMP pathway with an adenylate cyclase inhibitor had no significant effect on ASM-024-induced guinea pig trachea relaxation. Collectively, these findings show that ASM-024 elicits relaxation of β2-AR desensitized tracheal preparations and suggest that ASM-024 mediates smooth muscle relaxation through a different target and signaling pathway than β2-adrenergic receptor agonists. These findings suggest ASM-024

  6. Simulation analysis of ASM/Takács models in the BSM1 configuration.

    Science.gov (United States)

    Sorour, M T; Bahgat, L M F

    2006-10-01

    The present paper summarizes the outlines of a simulation analysis study conducted on the BSM1 (formerly the COST benchmark) configuration using activated sludge models (ASM1, ASM2d and ASM3) coupled to Takács settler model. The prime objective was to develop reliable simulation software programs to implement these complex models according to the working conditions of a realistic plant. The analysis focused on comparing the steady state predictions of models ASM1/ ASM3 when imposed to pulse/ step type disturbances on wastewater characteristics and control variables, then on assessing the capability of the simulated configuration for bio-P removal using model ASM2d. Section 1 of the paper briefly presents problem definition/ solution approach while section 2 demonstrates some examples showing the main indications of the simulation analysis. ASM1/ ASM3 predictions indicate the presence of some significant differences between both models that could be related to their underlying concepts. ASM2d simulations show that adverse effects on the permissible limit of effluent's ammonia concentration should be expected when the plant is operated to achieve dual nutrient removal.

  7. Significant issues and changes for ANSI/ASME OM-1 1981, part 1, ASME OMc code-1994, and ASME OM Code-1995, Appendix I, inservice testing of pressure relief devices in light water reactor power plants

    Energy Technology Data Exchange (ETDEWEB)

    Seniuk, P.J.

    1996-12-01

    This paper identifies significant changes to the ANSI/ASME OM-1 1981, Part 1, and ASME Omc Code-1994 and ASME OM Code-1995, Appendix I, {open_quotes}Inservice Testing of Pressure Relief Devices in Light-Water Reactor Power Plants{close_quotes}. The paper describes changes to different Code editions and presents insights into the direction of the code committee and selected topics to be considered by the ASME O&M Working Group on pressure relief devices. These topics include scope issues, thermal relief valve issues, as-found and as-left set-pressure determinations, exclusions from testing, and cold setpoint bench testing. The purpose of this paper is to describe some significant issues being addressed by the O&M Working Group on Pressure Relief Devices (OM-1). The writer is currently the chair of OM-1 and the statements expressed herein represents his personal opinion.

  8. ASM Based Synthesis of Handwritten Arabic Text Pages

    Directory of Open Access Journals (Sweden)

    Laslo Dinges

    2015-01-01

    Full Text Available Document analysis tasks, as text recognition, word spotting, or segmentation, are highly dependent on comprehensive and suitable databases for training and validation. However their generation is expensive in sense of labor and time. As a matter of fact, there is a lack of such databases, which complicates research and development. This is especially true for the case of Arabic handwriting recognition, that involves different preprocessing, segmentation, and recognition methods, which have individual demands on samples and ground truth. To bypass this problem, we present an efficient system that automatically turns Arabic Unicode text into synthetic images of handwritten documents and detailed ground truth. Active Shape Models (ASMs based on 28046 online samples were used for character synthesis and statistical properties were extracted from the IESK-arDB database to simulate baselines and word slant or skew. In the synthesis step ASM based representations are composed to words and text pages, smoothed by B-Spline interpolation and rendered considering writing speed and pen characteristics. Finally, we use the synthetic data to validate a segmentation method. An experimental comparison with the IESK-arDB database encourages to train and test document analysis related methods on synthetic samples, whenever no sufficient natural ground truthed data is available.

  9. ASM Based Synthesis of Handwritten Arabic Text Pages.

    Science.gov (United States)

    Dinges, Laslo; Al-Hamadi, Ayoub; Elzobi, Moftah; El-Etriby, Sherif; Ghoneim, Ahmed

    2015-01-01

    Document analysis tasks, as text recognition, word spotting, or segmentation, are highly dependent on comprehensive and suitable databases for training and validation. However their generation is expensive in sense of labor and time. As a matter of fact, there is a lack of such databases, which complicates research and development. This is especially true for the case of Arabic handwriting recognition, that involves different preprocessing, segmentation, and recognition methods, which have individual demands on samples and ground truth. To bypass this problem, we present an efficient system that automatically turns Arabic Unicode text into synthetic images of handwritten documents and detailed ground truth. Active Shape Models (ASMs) based on 28046 online samples were used for character synthesis and statistical properties were extracted from the IESK-arDB database to simulate baselines and word slant or skew. In the synthesis step ASM based representations are composed to words and text pages, smoothed by B-Spline interpolation and rendered considering writing speed and pen characteristics. Finally, we use the synthetic data to validate a segmentation method. An experimental comparison with the IESK-arDB database encourages to train and test document analysis related methods on synthetic samples, whenever no sufficient natural ground truthed data is available.

  10. Radiation-induced temperature shift of thhe ASME KIc curve

    International Nuclear Information System (INIS)

    Nanstad, R.K.; Haggag, F.M.; Iskander, S.K.

    1989-01-01

    The objective of this study was to determine the effects of neutron irradiation on the temperature shift and shape of the K Ic curve described in Sect. XI of the ASME Boiler and pressure Vessel Code. Two submerged-arc welds with copper contents of 0.23 and 0.31 wt % were commercially fabricated in 215-mm-thick plate. Charpy impact, tensile, dropweight, and compact specimens up to 203.2 mm thick were fabricated and tested to provide a large data for unirradiated material. Similar specimens with compacts up to 101.6 mm thick, irradiated at about 288 degree C to a mean fluence of about 1.6 times 10 19 neutrons/cm 2 in the Oak Ridge Research Reactor, were tested to provide a similarly large data base with which to evaluate the temperature shift and shape of the ASME K Ic curves. Testing was performed by both Oak Ridge National Laboratory and Materials Engineering Associates. Both linear-elastic and elastic-plastic fracture mechanics techniques were used to analyze test results. 3 refs., 4 figs., 1 tab

  11. Limitations of ASM1 and ASM3: a comparison based on batch oxygen uptake rate profiles from different full-scale wastewater treatment plants.

    Science.gov (United States)

    Guisasola, A; Sin, G; Baeza, J A; Carrera, J; Vanrolleghem, P A

    2005-01-01

    The two most popular models for the description of the biological COD removal are ASM1 and ASM3. However, some numerical inconsistencies arise when using these models to interpret the data obtained in short-term respirometric batch experiments. In this study, both models are fitted to four different respirometric batch profiles obtained with biomass from different WWTP. The parameter estimation results and the practical (local) identifiability are analysed, and the limitations of both models are discussed. The growth yield obtained by fitting ASM1 to the short-term respirometric batch profiles is higher than the default one, as well as the storage yield obtained by fitting ASM3 is lower than the default one. Based on these values, possible improvements to the modelling of the biological COD removal, such as the inclusion of simultaneous growth and storage on external substrate, are proposed.

  12. Phosphorus cycling in Montreal's food and urban agriculture systems.

    Directory of Open Access Journals (Sweden)

    Geneviève S Metson

    Full Text Available Cities are a key system in anthropogenic phosphorus (P cycling because they concentrate both P demand and waste production. Urban agriculture (UA has been proposed as a means to improve P management by recycling cities' P-rich waste back into local food production. However, we have a limited understanding of the role UA currently plays in the P cycle of cities or its potential to recycle local P waste. Using existing data combined with surveys of local UA practitioners, we quantified the role of UA in the P cycle of Montreal, Canada to explore the potential for UA to recycle local P waste. We also used existing data to complete a substance flow analysis of P flows in the overall food system of Montreal. In 2012, Montreal imported 3.5 Gg of P in food, of which 2.63 Gg ultimately accumulated in landfills, 0.36 Gg were discharged to local waters, and only 0.09 Gg were recycled through composting. We found that UA is only a small sub-system in the overall P cycle of the city, contributing just 0.44% of the P consumed as food in the city. However, within the UA system, the rate of recycling is high: 73% of inputs applied to soil were from recycled sources. While a Quebec mandate to recycle 100% of all organic waste by 2020 might increase the role of UA in P recycling, the area of land in UA is too small to accommodate all P waste produced on the island. UA may, however, be a valuable pathway to improve urban P sustainability by acting as an activity that changes residents' relationship to, and understanding of, the food system and increases their acceptance of composting.

  13. Phosphorus cycling in Montreal's food and urban agriculture systems.

    Science.gov (United States)

    Metson, Geneviève S; Bennett, Elena M

    2015-01-01

    Cities are a key system in anthropogenic phosphorus (P) cycling because they concentrate both P demand and waste production. Urban agriculture (UA) has been proposed as a means to improve P management by recycling cities' P-rich waste back into local food production. However, we have a limited understanding of the role UA currently plays in the P cycle of cities or its potential to recycle local P waste. Using existing data combined with surveys of local UA practitioners, we quantified the role of UA in the P cycle of Montreal, Canada to explore the potential for UA to recycle local P waste. We also used existing data to complete a substance flow analysis of P flows in the overall food system of Montreal. In 2012, Montreal imported 3.5 Gg of P in food, of which 2.63 Gg ultimately accumulated in landfills, 0.36 Gg were discharged to local waters, and only 0.09 Gg were recycled through composting. We found that UA is only a small sub-system in the overall P cycle of the city, contributing just 0.44% of the P consumed as food in the city. However, within the UA system, the rate of recycling is high: 73% of inputs applied to soil were from recycled sources. While a Quebec mandate to recycle 100% of all organic waste by 2020 might increase the role of UA in P recycling, the area of land in UA is too small to accommodate all P waste produced on the island. UA may, however, be a valuable pathway to improve urban P sustainability by acting as an activity that changes residents' relationship to, and understanding of, the food system and increases their acceptance of composting.

  14. A descriptive study of bicycle helmet use in Montreal, 2011.

    Science.gov (United States)

    Grenier, Tara; Deckelbaum, Dan L; Boulva, Kerianne; Drudi, Laura; Feyz, Mitra; Rodrigue, Nathalie; Tze, Nancy; Fata, Paola; Khwaja, Kosar; Chughtai, Talat; Razek, Tarek

    2013-09-17

    The purpose of this study was to describe bicycle helmet use among Montreal cyclists as a step towards injury prevention programming. Using a cross-sectional study design, cyclists were observed during 60-minute periods at 22 locations on the island of Montreal. There were 1-3 observation periods per location. Observations took place between August 16 and October 31, 2011. Standard statistical methods were used, unadjusted and adjusted odds ratios and 95% confidence interval were calculated. A total of 4,789 cyclists were observed. The helmet-wearing proportion of all cyclists observed was 46% (95% CI 44-47). Women had a higher helmet-wearing proportion than men (50%, 95% CI 47-52 vs. 44%, 95% CI 42-45, respectively). Youth had the highest helmet-wearing proportion (73%, 95% CI 64-81), while young adults had the lowest (34%, 95% CI 30-37). Visible minorities were observed wearing a helmet 29% (95% CI 25-34) of the time compared to Caucasians, 47% (95% CI 46-49). BIXI (bike sharing program) riders were observed wearing a helmet 12% (95% CI 10-15) of the time compared to riders with their own bike, 51% (95% CI 49-52). Although above the national average, bicycle helmet use in Montreal is still considerably low given that the majority of cyclists do not wear a helmet. Injury Prevention Programs could target the entire cyclist population, but special attention may be warranted in specific groups such as young men, visible minorities, BIXI riders, and those riding in tourist areas. Additionally, a collaborative enterprise with the bicycle sharing system BIXI Montreal™ could prove to be fruitful in addressing the availability of bike helmets for BIXI riders.

  15. Performance of the Montreal classification for inflammatory bowel diseases

    Science.gov (United States)

    Spekhorst, Lieke M; Visschedijk, Marijn C; Alberts, Rudi; Festen, Eleonora A; van der Wouden, Egbert-Jan; Dijkstra, Gerard; Weersma, Rinse K

    2014-01-01

    AIM: To validate the Montreal classification system for Crohn’s disease (CD) and ulcerative colitis (UC) within the Netherlands. METHODS: A selection of 20 de-identified medical records with an appropriate representation of the inflammatory bowel disease (IBD) sub phenotypes were scored by 30 observers with different professions (gastroenterologist specialist in IBD, gastroenterologist in training and IBD-nurses) and experience level with IBD patient care. Patients were classified according to the Montreal classification. In addition, participants were asked to score extra-intestinal manifestations (EIM) and disease severity in CD based on their clinical judgment. The inter-observer agreement was calculated by percentages of correct answers (answers identical to the “expert evaluation”) and Fleiss-kappa (κ). Kappa cut-offs: 0.8 excellent. RESULTS: The inter-observer agreement was excellent for diagnosis (κ = 0.96), perianal disease (κ = 0.92) and disease location in CD (κ = 0.82) and good for age of onset (κ = 0.67), upper gastrointestinal disease (κ = 0.62), disease behaviour in CD (κ = 0.79) and disease extent in UC (κ = 0.65). Disease severity in UC was scored poor (κ = 0.23). The additional items resulted in a good inter-observer agreement for EIM (κ = 0.68) and a moderate agreement for disease severity in CD (κ = 0.44). Percentages of correct answers over all Montreal items give a good reflection of the inter-observer agreement (> 80%), except for disease severity (48%-74%). IBD-nurses were significantly worse in scoring upper gastrointestinal disease in CD compared to gastroenterologists (P = 0.008) and gastroenterologists in training (P = 0.040). Observers with less than 10 years of experience were significantly better at scoring UC severity than observers with 10-20 years (P = 0.003) and more than 20 years (P = 0.003) of experience with IBD patient care. Observers with 10-20 years of experience with IBD patient care were significantly

  16. ASME Code requirements for multi-canister overpack design and fabrication

    International Nuclear Information System (INIS)

    SMITH, K.E.

    1998-01-01

    The baseline requirements for the design and fabrication of the MCO include the application of the technical requirements of the ASME Code, Section III, Subsection NB for containment and Section III, Subsection NG for criticality control. ASME Code administrative requirements, which have not historically been applied at the Hanford site and which have not been required by the US Nuclear Regulatory Commission (NRC) for licensed spent fuel casks/canisters, were not invoked for the MCO. As a result of recommendations made from an ASME Code consultant in response to DNFSB staff concerns regarding ASME Code application, the SNF Project will be making the following modifications: issue an ASME Code Design Specification and Design Report, certified by a Registered Professional Engineer; Require the MCO fabricator to hold ASME Section III or Section VIII, Division 2 accreditation; and Use ASME Authorized Inspectors for MCO fabrication. Incorporation of these modifications will ensure that the MCO is designed and fabricated in accordance with the ASME Code. Code Stamping has not been a requirement at the Hanford site, nor for NRC licensed spent fuel casks/canisters, but will be considered if determined to be economically justified

  17. Integrin and GPCR Crosstalk in the Regulation of ASM Contraction Signaling in Asthma.

    Science.gov (United States)

    Teoh, Chun Ming; Tam, John Kit Chung; Tran, Thai

    2012-01-01

    Airway hyperresponsiveness (AHR) is one of the cardinal features of asthma. Contraction of airway smooth muscle (ASM) cells that line the airway wall is thought to influence aspects of AHR, resulting in excessive narrowing or occlusion of the airway. ASM contraction is primarily controlled by agonists that bind G protein-coupled receptor (GPCR), which are expressed on ASM. Integrins also play a role in regulating ASM contraction signaling. As therapies for asthma are based on symptom relief, better understanding of the crosstalk between GPCRs and integrins holds good promise for the design of more effective therapies that target the underlying cellular and molecular mechanism that governs AHR. In this paper, we will review current knowledge about integrins and GPCRs in their regulation of ASM contraction signaling and discuss the emerging concept of crosstalk between the two and the implication of this crosstalk on the development of agents that target AHR.

  18. Bicycle access to downtown Montreal : investing in a better future

    Energy Technology Data Exchange (ETDEWEB)

    Jolicoeur, M. [Velo Quebec, Montreal, PQ (Canada)

    2005-07-01

    The cycling community has long since expressed concern about the need to facilitate and encourage bicycle access to downtown Montreal. The municipality of Montreal in cooperation with Velo Quebec have initiated a process that responds to a specific need to improve safety for cyclists. A study was conducted to analyse the situation, including a portrait of the cycling situation downtown as well as a review of the best practices in ten comparable cities. Various scenarios were then outlined for facilitating bicycle access and mobility downtown. Guiding principles of this study are to include the comfort and safety of cyclists as well as respect for the priority of pedestrians and transit. The paper makes several recommendations and proposals including adding bike lanes on major arteries; ensuring wide bus and bike reserved lanes; as well as contra-flow bike lanes on residential one-way streets. The plan also proposes that racks be installed in numerous locations, including on sidewalks, on streets and at public and private buildings in order to address the shortage of bicycle parking. The paper concludes that only small adjustments to standards are required to put these measures in place. The greatest challenge lies in changing attitudes towards the bicycle as a preferred mode of transportation. 2 refs., 7 figs.

  19. ASM1-based activated sludge model with biopolymer kinetics for integrated simulation of membrane bioreactors for wastewater treatment

    OpenAIRE

    Janus, Tomasz; Ulanicki, Bogumil

    2015-01-01

    This paper presents an activated sludge model suitable for modelling membrane bioreactors (MBRs) for wastewater treatment. The model, later referred to as combined EPS and SMP production ASM1-based model (CES-ASM1), extends Activated Sludge Model No. 1 (ASM1) with biokinetics of two types of bacterial biopolymers: soluble microbial products (SMP) and extracellular polymeric substances (EPS). The biopolymer kinetics in CES-ASM1 are, in their majority, borrowed from Laspidou and Rittmann[1] ...

  20. Chapter 9: Electronics

    International Nuclear Information System (INIS)

    Grupen, Claus; Shwartz, Boris A.

    2006-01-01

    Sophisticated front-end electronics are a key part of practically all modern radiation detector systems. This chapter introduces the basic principles and their implementation. Topics include signal acquisition, electronic noise, pulse shaping (analog and digital), and data readout techniques

  1. Chapter 9: Reliability

    Energy Technology Data Exchange (ETDEWEB)

    Algora, Carlos; Espinet-Gonzalez, Pilar; Vazquez, Manuel; Bosco, Nick; Miller, David; Kurtz, Sarah; Rubio, Francisca; McConnell,Robert

    2016-04-15

    This chapter describes the accumulated knowledge on CPV reliability with its fundamentals and qualification. It explains the reliability of solar cells, modules (including optics) and plants. The chapter discusses the statistical distributions, namely exponential, normal and Weibull. The reliability of solar cells includes: namely the issues in accelerated aging tests in CPV solar cells, types of failure and failures in real time operation. The chapter explores the accelerated life tests, namely qualitative life tests (mainly HALT) and quantitative accelerated life tests (QALT). It examines other well proven and experienced PV cells and/or semiconductor devices, which share similar semiconductor materials, manufacturing techniques or operating conditions, namely, III-V space solar cells and light emitting diodes (LEDs). It addresses each of the identified reliability issues and presents the current state of the art knowledge for their testing and evaluation. Finally, the chapter summarizes the CPV qualification and reliability standards.

  2. Basic Principles - Chapter 6

    Data.gov (United States)

    National Aeronautics and Space Administration — This chapter described at a very high level some of the considerations that need to be made when designing algorithms for a vehicle health management application....

  3. Nuclear component design ontology building based on ASME codes

    International Nuclear Information System (INIS)

    Bao Shiyi; Zhou Yu; He Shuyan

    2005-01-01

    The adoption of ontology analysis in the study of concept knowledge acquisition and representation for the nuclear component design process based on computer-supported cooperative work (CSCW) makes it possible to share and reuse numerous concept knowledge of multi-disciplinary domains. A practical ontology building method is accordingly proposed based on Protege knowledge model in combination with both top-down and bottom-up approaches together with Formal Concept Analysis (FCA). FCA exhibits its advantages in the way it helps establish and improve taxonomic hierarchy of concepts and resolve concept conflict occurred in modeling multi-disciplinary domains. With Protege-3.0 as the ontology building tool, a nuclear component design ontology based ASME codes is developed by utilizing the ontology building method. The ontology serves as the basis to realize concept knowledge sharing and reusing of nuclear component design. (authors)

  4. 76 FR 11191 - Hazardous Materials: Adoption of ASME Code Section XII and the National Board Inspection Code

    Science.gov (United States)

    2011-03-01

    ... Hazardous Materials: Adoption of ASME Code Section XII and the National Board Inspection Code AGENCY... the electronic availability of the American Society of Mechanical Engineers' (ASME) Boiler and... the ANPRM published on December 23, 2010 (ANPRM; 75 FR 80765). The ASME Boiler and Pressure Vessel...

  5. Regulation of dynein-mediated autophagosomes trafficking by ASM in CASMCs.

    Science.gov (United States)

    Xu, Ming; Zhang, Qiufang; Li, Pin-Lan; Nguyen, Thaison; Li, Xiang; Zhang, Yang

    2016-01-01

    Acid sphingomyelinase (ASM; gene symbol Smpd1) has been shown to play a crucial role in autophagy maturation by controlling lysosomal fusion with autophagosomes in coronary arterial smooth muscle cells (CASMCs). However, the underlying molecular mechanism by which ASM controls autophagolysosomal fusion remains unknown. In primary cultured CASMCs, lysosomal Ca2+ induced by 7-ketocholesterol (7-Ket, an atherogenic stimulus and autophagy inducer) was markedly attenuated by ASM deficiency or TRPML1 gene silencing suggesting that ASM signaling is required for TRPML1 channel activity and subsequent lysosomal Ca(2+) release. In these CASMCs, ASM deficiency or TRPML1 gene silencing markedly inhibited 7-Ket-induced dynein activation. In addition, 7-Ket-induced autophagosome trafficking, an event associated with lysosomal Ca(2+) release and dynein activity, was significantly inhibited in ASM-deficient (Smpd1(-/-)) CASMCs compared to that in Smpd1(+/+) CASMCs. Finally, overexpression of TRPML1 proteins restored 7-Ket-induced lysosomal Ca(2+) release and autophagosome trafficking in Smpd1-/- CASMCs. Collectively, these results suggest that ASM plays a critical role in regulating lysosomal TRPML1-Ca(2+) signaling and subsequent dynein-mediated autophagosome trafficking, which leads its role in controlling autophagy maturation in CASMCs under atherogenic stimulation.

  6. Passport of global nuclear business. ASME code certificate acquirement and inspection practices

    International Nuclear Information System (INIS)

    Kawabata, Hiroyuki; Terajima, Makoto; Anami, Kazuhiro

    2010-01-01

    There are possibilities of Japanese nuclear industries to participate in global business such as new and additional construction of nuclear power plants in US and also Asian and other developing countries in the world. It is requisite to acquire ASME code certificate for global business participation, just as passport. This article consists of five papers on present status of ASME code certificate acquirement and inspection practices of nuclear components vendors in the area of Japanese nuclear business. Activities of JSME Committee on Power Generation Facility Codes to make JSME codes corresponded to ASME nuclear codes and standards for their international deployment are also described. (T. Tanaka)

  7. [Ca2+]i oscillations in ASM: relationship with persistent airflow obstruction in asthma.

    Science.gov (United States)

    Sweeney, David; Hollins, Fay; Gomez, Edith; Saunders, Ruth; Challiss, R A John; Brightling, Christopher E

    2014-07-01

    The cause of airway smooth muscle (ASM) hypercontractility in asthma is not fully understood. The relationship of spontaneous intracellular calcium oscillation frequency in ASM to asthma severity was investigated. Oscillations were increased in subjects with impaired lung function abolished by extracellular calcium removal, attenuated by caffeine and unaffected by verapamil or nitrendipine. Whether modulation of increased spontaneous intracellular calcium oscillations in ASM from patients with impaired lung function represents a therapeutic target warrants further investigation. © 2014 The Authors. Respirology published by Wiley Publishing Asia Pty Ltd on behalf of Asian Pacific Society of Respirology.

  8. Clinical applications of positron emission tomography at Montreal Neurological Institute

    International Nuclear Information System (INIS)

    Morgan, P.P.

    1983-01-01

    The Montreal Neurological Institute occupies a leading position in positron emission tomography (PET) of the brain with the help of the following three techological gains: they have acquired a 'Therascan' positron emission tomograph manufactured by Atomic Energy of Canada Ltd.; also, a 'Baby Cyclotron' manufactured by Japan Steel Works Ltd.; and they have written a computer program to display the results in colour. Four short-lived isotopes are used; 11 C, 15 O, 18 F, 13 N. Studies of the oxygen uptake of tumours, their glucose metabolism (as monitored by 18 F labelled 2-fluoro-2-deoxyglucose), and their uptake of therapeutic agents, provide valuable research and diagnostic information. PET is also being used to study epilepsy and cerebrovascular disease

  9. Modeling seasonal variation of hip fracture in Montreal, Canada.

    Science.gov (United States)

    Modarres, Reza; Ouarda, Taha B M J; Vanasse, Alain; Orzanco, Maria Gabriela; Gosselin, Pierre

    2012-04-01

    The investigation of the association of the climate variables with hip fracture incidences is important in social health issues. This study examined and modeled the seasonal variation of monthly population based hip fracture rate (HFr) time series. The seasonal ARIMA time series modeling approach is used to model monthly HFr incidences time series of female and male patients of the ages 40-74 and 75+ of Montreal, Québec province, Canada, in the period of 1993-2004. The correlation coefficients between meteorological variables such as temperature, snow depth, rainfall depth and day length and HFr are significant. The nonparametric Mann-Kendall test for trend assessment and the nonparametric Levene's test and Wilcoxon's test for checking the difference of HFr before and after change point are also used. The seasonality in HFr indicated sharp difference between winter and summer time. The trend assessment showed decreasing trends in HFr of female and male groups. The nonparametric test also indicated a significant change of the mean HFr. A seasonal ARIMA model was applied for HFr time series without trend and a time trend ARIMA model (TT-ARIMA) was developed and fitted to HFr time series with a significant trend. The multi criteria evaluation showed the adequacy of SARIMA and TT-ARIMA models for modeling seasonal hip fracture time series with and without significant trend. In the time series analysis of HFr of the Montreal region, the effects of the seasonal variation of climate variables on hip fracture are clear. The Seasonal ARIMA model is useful for modeling HFr time series without trend. However, for time series with significant trend, the TT-ARIMA model should be applied for modeling HFr time series. Copyright © 2011 Elsevier Inc. All rights reserved.

  10. The Montreal Lectures: 2 August - 2 October, 1944

    International Nuclear Information System (INIS)

    Arsenault, J.E.

    2007-01-01

    The Second World War began in the summer of 1939 and spurred atomic science in the direction of weapons development. The United Kingdom (U.K.) was far ahead until about the summer of 1941 at which time the United States (U.S.) began to have serious interest in atomic weapons. Seen from Europe, the U.S. was a greater distance from the theatre of war and was deemed to be a safer place to conduct atomic research. In addition to good research centres it also had greater financial, manpower, and material resources. Early attempts at full collaboration between the U.K. and the U.S. met with little success and this led to the formation of a joint British-Canadian atomic weapons effort in 1942, with research laboratories located in Montreal, which were well up and running by spring 1943. The Montreal laboratory (ML) initially was administered by the National Research Council (NRC) and scientific direction was provided by the U.K. The ML was the foundation from which the Canadian nuclear industry evolved to the present time. Interest in atomic weapons development by the U.S. had been greatly accelerated by the Japanese attack on Pearl Harbour on 7 December 1941. By the beginning of 1943 it was spending 10 times as much as the U.K. on atomic weapons research. From then on, the U.S. set the Allied agenda for the development of atomic weapons, in varying degrees of collaboration with the U.K. and Canada. This spending which grew to about $2B by the middle of 1945, was directed by the U.S. Army Corps of Engineers under the Manhattan Project, officially established on 13 August 1942, and led by Gen. Leslie R. Groves From 17 September 1942. (author)

  11. Strengthening the Montreal Protocol: Does it cool down the greenhouse?

    International Nuclear Information System (INIS)

    Den Elzen, M.G.J.; Swart, R.J.; Rotmans, J.

    1992-01-01

    Strengthening of the Montreal Protocol is recently being negotiated in London in 1990 in order to achieve further reductions of the regulated CFCs and to include possibly more substances. The implications of different policies with respect to control of ozone depleting substances for climate change are analysed, including the proposed substitution by HCFCs and HFCs, carbon tetrachloride and methylchloroform. A special halocarbon module was developed within the framework of RIVM's Integrated Model to Assess the Greenhouse Effect (IMAGE). IMAGE is a parametrized science based policy model and has been developed to give policy agencies a concise overview of the quantitative aspects of the greenhouse problem, to evaluate various policy options concerning climate change and to serve as a means of communication. It is concluded, from simulations with the halocarbon module, that it is of primary importance to achieve a further reduction of the regulated CFCs compared to the Montreal Protocol with compliance by as many countries as possible. From the perspective of the greenhouse effect the inclusion of longer lived halocarbons, such as carbon tetrachloride and HCFC-22 in the protocol come second. The application of methylchloroform, halons and HCFCs and HFCs with lower global warming potentials (GWPs) than HCFC-22 contributes only marginally to the greenhouse effect in comparison with the much more important greenhouse gases carbon dioxide, methane, ozone and nitrous oxide. Especially if further growth of the total production of HCFCs after complete replacement of the present CFCs can be avoided by using these alternatives with a lower GWP, these substances could therefore be tolerated in a transition period, from the perspective of global warming. 13 figs., 3 tabs., 29 refs

  12. The ASM Curriculum Guidelines for Undergraduate Microbiology: A Case Study of the Advocacy Role of Societies in Reform Efforts.

    Science.gov (United States)

    Horak, Rachel E A; Merkel, Susan; Chang, Amy

    2015-05-01

    A number of national reports, including Vision and Change in Undergraduate Biology Education: A Call to Action, have called for drastic changes in how undergraduate biology is taught. To that end, the American Society for Microbiology (ASM) has developed new Curriculum Guidelines for undergraduate microbiology that outline a comprehensive curriculum for any undergraduate introductory microbiology course or program of study. Designed to foster enduring understanding of core microbiology concepts, the Guidelines work synergistically with backwards course design to focus teaching on student-centered goals and priorities. In order to qualitatively assess how the ASM Curriculum Guidelines are used by educators and learn more about the needs of microbiology educators, the ASM Education Board distributed two surveys to the ASM education community. In this report, we discuss the results of these surveys (353 responses). We found that the ASM Curriculum Guidelines are being implemented in many different types of courses at all undergraduate levels. Educators indicated that the ASM Curriculum Guidelines were very helpful when planning courses and assessments. We discuss some specific ways in which the ASM Curriculum Guidelines have been used in undergraduate classrooms. The survey identified some barriers that microbiology educators faced when trying to adopt the ASM Curriculum Guidelines, including lack of time, lack of financial resources, and lack of supporting resources. Given the self-reported challenges to implementing the ASM Curriculum Guidelines in undergraduate classrooms, we identify here some activities related to the ASM Curriculum Guidelines that the ASM Education Board has initiated to assist educators in the implementation process.

  13. High Level Analysis, Design and Validation of Distributed Mobile Systems with CoreASM

    Science.gov (United States)

    Farahbod, R.; Glässer, U.; Jackson, P. J.; Vajihollahi, M.

    System design is a creative activity calling for abstract models that facilitate reasoning about the key system attributes (desired requirements and resulting properties) so as to ensure these attributes are properly established prior to actually building a system. We explore here the practical side of using the abstract state machine (ASM) formalism in combination with the CoreASM open source tool environment for high-level design and experimental validation of complex distributed systems. Emphasizing the early phases of the design process, a guiding principle is to support freedom of experimentation by minimizing the need for encoding. CoreASM has been developed and tested building on a broad scope of applications, spanning computational criminology, maritime surveillance and situation analysis. We critically reexamine here the CoreASM project in light of three different application scenarios.

  14. Analysis of preservice inspection relief requests and recommendations for ASME code changes

    International Nuclear Information System (INIS)

    Cook, J.F.

    1985-05-01

    NRC regulations require that preservice inspection (PSI) of nuclear plants be performed in accordance with referenced editions and addenda of Division 1 rules of Section XI, ''Rules for Inservice Inspection of Nuclear Power Plant Components'', of the ASME Boiler and Pressure Vessel Code (ASME Code). The regulations permit applicants to request and obtain relief from the NRC from specific ASME Code requirements that are determined to be impractical. Applicant requests for relief from preservice inspection (PSI) requirements were compiled and analyzed. From this data, covering a total of 178 relief requests, common problems with examination requirements were identified. Changes to examination requirements to solve selected problems are proposed. By following later ASME Code requirements, 46 out of the 178 relief requests can be eliminated. Implementing proposed Code changes would eliminate another 25 relief requests, leaving 107 relief requests out of the original 178 relief requests covered by this survey

  15. Estimates of margins in ASME Code strength values for stainless steel nuclear piping

    International Nuclear Information System (INIS)

    Ware, A.G.

    1995-01-01

    The margins in the ASME Code stainless steel allowable stress values that can be attributed to the variations in material strength are evaluated for nuclear piping steels. Best-fit curves were calculated for the material test data that were used to determine allowable stress values for stainless steels in the ASME Code, supplemented by more recent data, to estimate the mean stresses. The mean yield stresses from the test data are about 15 to 20% greater than the ASME Code yield stress values (the stainless steel S m values are based on the yield stress). The ASME Code yield stress values are estimated to approximately coincide with the 97% confidence limit from the test data. The mean and 97% confidence limit values can be used in probabilistic risk assessments of nuclear piping

  16. 115-year-old society knows how to reach young scientists: ASM Young Ambassador Program.

    Science.gov (United States)

    Karczewska-Golec, Joanna

    2015-12-25

    With around 40,000 members in more than 150 countries, American Society for Microbiology (ASM) faces the challenge of meeting very diverse needs of its increasingly international members base. The newly launched ASM Young Ambassador Program seeks to aid the Society in this effort. Equipped with ASM conceptual support and financing, Young Ambassadors (YAs) design and pursue country-tailored approaches to strengthen the Society's ties with local microbiological communities. In a trans-national setting, the active presence of YAs at important scientific events, such as 16th European Congress on Biotechnology, forges new interactions between ASM and sister societies. The paper presents an overview of the Young Ambassadors-driven initiatives at both global and country levels, and explores the topic of how early-career scientists can contribute to science diplomacy and international relations. Copyright © 2014 Elsevier B.V. All rights reserved.

  17. Hurrah for Chapter Books.

    Science.gov (United States)

    Jones, Glenowyn L.

    This annotated bibliography contains a list of 42 recent Chapter Books. The bibliography is divided into the following topics: Adventure-Survival (3 titles); Autobiography-Biography (3 titles); Death (1 title); Easy Readers (8 titles); Good Reading (12 titles); Historical Fiction (10 titles); Mystery (3 titles); Newbery Award Winner, 2000; and…

  18. Water resources (Chapter 12)

    Science.gov (United States)

    Thomas C. Brown; Romano Foti; Jorge Ramirez

    2012-01-01

    In this chapter, we focus on the vulnerability of U.S. freshwater supplies considering all lands, not just forest and rangelands. We do not assess the condition of those lands or report on how much of our water supply originates on lands of different land covers or ownerships, because earlier Resources Planning Act (RPA) Assessment work addressed these topics....

  19. Floristics [Chapter 3

    Science.gov (United States)

    J. D. Haines; R. C. Musselman; C. M. Regan

    1994-01-01

    The initial habitat classification as described in Chapter 2 was conducted in 1986 and 1987 based upon field identification of plant species. A field collection of vascular plant species was made during the 1988, 1989, and 1990 summer seasons. The plant species collected were identified and verified in cooperation with the Rocky Mountain Herbarium at the University of...

  20. Nursery management [Chapter 16

    Science.gov (United States)

    Kim M. Wilkinson

    2009-01-01

    This handbook provides an overview of the factors that go into starting and operating a native plant nursery. Management includes all aspects of working with plants in all their phases of growth as described in Chapter 3, Crop Planning and Developing Propagation Protocols. Management also includes working with the community; organizing materials and infrastructure;...

  1. Chapter 0: Executive summary

    International Nuclear Information System (INIS)

    1995-01-01

    This chapter deals with the background (Gabcikovo hydro power scheme was input in October 1992), project objective, project framework, equipment, establishment of the integrated modelling system, model setup, calibration and validation, definitions of scenarios for model application and with the results of model applications

  2. Research recommendations [Chapter 10

    Science.gov (United States)

    Daniel G. Neary; Alvin L. Medina; John N. Rinne

    2012-01-01

    This chapter contains a number of research recommendations that have developed from the 15 years of research on the UVR conducted by the Southwest Watershed Science Team, as well as from insights from key cooperators and contacts. It is meant to be our best insight as to where efforts should go now. Achieving these recommendations will depend on a number of factors,...

  3. Chapter 8. Data Analysis

    Science.gov (United States)

    Lyman L. McDonald; Christina D. Vojta; Kevin S. McKelvey

    2013-01-01

    Perhaps the greatest barrier between monitoring and management is data analysis. Data languish in drawers and spreadsheets because those who collect or maintain monitoring data lack training in how to effectively summarize and analyze their findings. This chapter serves as a first step to surmounting that barrier by empowering any monitoring team with the basic...

  4. Forestry [Chapter 11

    Science.gov (United States)

    H. Gyde Lund; William A. Befort; James E. Brickell; William M. Ciesla; Elizabeth C. Collins; Raymond L. Czaplewski; Attilio Antonio Disperati; Robert W. Douglass; Charles W. Dull; Jerry D. Greer; Rachel Riemann Hershey; Vernon J. LaBau; Henry Lachowski; Peter A. Murtha; David J. Nowak; Marc A. Roberts; Pierre Schram; Mahadev D. Shedha; Ashbindu Singh; Kenneth C. Winterberger

    1997-01-01

    Foresters and other resource managers have used aerial photographs to help manage resources since the late 1920s. As discussed in chapter 1, however, it was not until the mid-1940s that their use became common. Obtaining photographic coverage was always a problem. For many areas of the world, reasonably complete coverage did not exist until after World War II. In...

  5. Chapter 3: Wood Decay

    Science.gov (United States)

    Dan Cullen

    2014-01-01

    A significant portion of global carbon is sequestered in forest systems. Specialized fungi have evolved to efficiently deconstruct woody plant cell walls. These important decay processes generate litter, soil bound humic substances, or carbon dioxide and water. This chapter reviews the enzymology and molecular genetics of wood decay fungi, most of which are members of...

  6. Sustainable careers: Introductory chapter

    NARCIS (Netherlands)

    Heijden, B.I.J.M. van der; Vos, A. de; Vos, A. de; Heijden, B.I.J.M. van der

    2015-01-01

    In this introductory chapter we will introduce the concept of ‘sustainable careers’ within the broader framework of contemporary careers. Departing from changes in the career context with regard to the dimensions of time, social space, agency and meaning, we advocate a fresh perspective on careers

  7. Tundra, Chapter 5

    Science.gov (United States)

    K. Nadelhoffer; L.H. Geiser

    2011-01-01

    The North American Arctic, comprising the Tundra and Arctic Cordillera ecoregions (CEC 1997, Chapter 2), covers more than 3 million km2 (300 million ha), and accounts for nearly 14 percent of the North American land mass. The North American Arctic also constitutes about 20 percent of the much larger circumpolar Arctic shared by Canada, the United...

  8. Chapter 3: Energy Security

    Energy Technology Data Exchange (ETDEWEB)

    Foust, Thomas D.; Arent, Doug; de Carvalho Macedo, Isaias; Goldemberg, Jose; Hoysala, Chanakya; Filho, Rubens Maciel; Nigro, Francisco E. B.; Richard, Tom L.; Saddler, Jack; Samseth, Jon; Somerville, Chris R.

    2015-04-01

    This chapter considers the energy security implications and impacts of bioenergy. We provide an assessment to answer the following questions: What are the implications for bioenergy and energy security within the broader policy environment that includes food and water security, development, economic productivity, and multiple foreign policy aspects? What are the conditions under which bioenergy contributes positively to energy security?

  9. NRC needs and their implementation-ASME Section IX code

    International Nuclear Information System (INIS)

    Liaw, B.D.

    1985-01-01

    The guiding principle from the onset of government regulation for the peaceful use of nuclear energy has been to prescribe only the minimum requirements that are needed for safety. In the pioneer regulators' collective mind, the technical details could be left to the regulated industry through its agents like NSSS vendors and A/E's and their surrogate organizations like ASME, ANS, AIF, etc. However, it has evolved through the years, due either to the bureaucratic momentum or the vacuum in industry leadership, into a situation where one sees an ever increasing number of detailed ''requirements'' prescribed by the regulators. Within the scope of activities covered by Section XI, there is no exception: e.g., NUREG-067, -0531 -1061; NUREG-0313 Rev. 0, Rev. 1, and now Rev. 2; IE Bulletins 82-03, 83-02; and Generic Letters 84-11, and 84-07, etc. for one issue of pipe crack alone; and there are more to come. There appears a consensus among all concerned parties including regulators that this is not a desirable situation and that something must be done to reverse this trend. The purpose of this discussion is, therefore, to explore the areas where the Section XI Code can be restructured to meet this need, and to seek ideas from the representatives of the regulated industry on the methods of implementation that are effective, efficient, and acceptable to all concerned parties

  10. ASME Section XI trends in developing nuclear codes and standards

    International Nuclear Information System (INIS)

    Hedden, O.F.

    1995-01-01

    When the author began working on nuclear power many years ago, he knew that perfection was the only acceptable technical standard. Unfortunately, this became an obsession with perfection that has had unfavorable consequences in some of the non-technical areas of work in ASME nuclear power Codes and Standards. However, the economic problems of the nuclear power industry now demand a more pragmatic approach if the industry is to continue. Not only does each item considered for action need to be evaluated to criteria that may in some cases be less than perfection, but one needs to consider whether it contributes tangibly to either safety or to reduction in technical or administrative burden. These should be the governing, criteria. The introduction of risk-based inspection methodologies will certainly be an important element in doing this successfully. One needs to consider these criteria collectively, as one discusses each item at the committee level, and individually, as one votes on each item. In the past, the author has been concerned that the industry was not acting quickly enough in taking advantage of opportunities offered by the Code to increase safety or to reduce cost. While he still has some concern, he thinks communication channels have been greatly improved. Now he is becoming more concerned with both the collective and individual actions that delay beneficial changes. The second part of the author's talk has to do with the relevance of the code committees in the nuclear power industry regulatory process

  11. Measurement of large ground motions with the ASM gage

    International Nuclear Information System (INIS)

    Wright, B.L.; Alrick, K.R.; Fritz, J.N.

    1994-01-01

    Conversion of the energy from undergound explosions to distant seismic signals involves hydrodynamic flows sampling a wide range of pressures. For lower pressures a larger portion of the initial wave motion must be measured to obtain definitive results. The intermediate pressure range, where the initial wave is strong enough to destroy most instrumentation but does not contain definitive information in its initial amplitude, presents special difficulties. We present design considerations for an experiment implementing the ASM gage principle (induction of eddy currents in a moving conducting plate) that can sample wave motion for many milliseconds. In essence we hang a large metal plate (large in area) on a wall and watch the free-surface release. This is not an in-itu measurement of the wave profile because the incoming wave is modififed by the release propagating backward from the wall. However, this a relatively clean modification of the incoming wave and is a situation commonly handled in many shock-wave experiments. copyright American Institute of Physics

  12. SDZ ASM 981: an emerging safe and effective treatment for atopic dermatitis.

    Science.gov (United States)

    Luger, T; Van Leent, E J; Graeber, M; Hedgecock, S; Thurston, M; Kandra, A; Berth-Jones, J; Bjerke, J; Christophers, E; Knop, J; Knulst, A C; Morren, M; Morris, A; Reitamo, S; Roed-Petersen, J; Schoepf, E; Thestrup-Pedersen, K; Van Der Valk, P G; Bos, J D

    2001-04-01

    SDZ ASM 981 is a selective inhibitor of the production of pro-inflammatory cytokines from T cells and mast cells in vitro. It is the first ascomycin macrolactam derivative under development for the treatment of inflammatory skin diseases. This study was designed to determine the safety and efficacy of SDZ ASM 981 cream at concentrations of 0.05%, 0.2%, 0.6% and 1.0% in the treatment of patients with atopic dermatitis and to select the concentration to be used in phase III studies. This was a double-blind, randomized, parallel-group, multicentre dose-finding study. A total of 260 patients were randomly assigned to treatment with SDZ ASM 981 cream at concentrations of 0.05%, 0.2%, 0.6%, or 1.0%, matching vehicle cream, or the internal control 0.1% betamethasone-17-valerate cream (BMV). Treatment was given twice daily for up to 3 weeks. A clear dose-response relationship for SDZ ASM 981 was evident, with 0.2%, 0.6% and 1.0% SDZ ASM 981 creams all being significantly more effective than vehicle (P = 0.041, 0.001 and 0.008, respectively) in terms of baseline to end-point changes in the Eczema Area Severity Index (EASI) and pruritus score. The 1.0% cream was the most effective SDZ ASM 981 concentration. BMV was more effective than the SDZ ASM 981 creams tested in this study. It appears that the efficacy plateau was not reached with the SDZ ASM 981 creams within 3 weeks treatment. SDZ ASM 981 was well tolerated. Burning or a feeling of warmth were the only adverse events reported more frequently in the 0.6% and 1.0% SDZ ASM 981 treatment groups than in the vehicle treatment group (42.9%, 48.9% and 34.9%, respectively). Few systemic adverse events were reported during the study (headache was the most frequent systemic event reported by 15 of 252 patients) and none was considered to be related to treatment. The local tolerability profile of the 1.0% cream was similar to that of the lower concentrations. 1.0% SDZ ASM 981 cream, which was shown to be safe, well tolerated and

  13. ASME nuclear codes and standards: Scope of coverage and current initiatives

    International Nuclear Information System (INIS)

    Eisenberg, G. M.

    1995-01-01

    The objective of this paper is to address the broad scope of coverage of nuclear codes, standards and guides produced and administered by the American Society of Mechanical Engineers (ASME). Background information is provided regarding the evolution of the present activities. Details are provided on current initiatives intended to permit ASME to meet the needs of a changing nuclear industry on a worldwide scale. During the early years of commercial nuclear power, ASME produced a code for the construction of nuclear vessels used in the reactor coolant pressure boundary, containment and auxiliary systems. In response to industry growth, ASME Code coverage soon broadened to include rules for construction of other nuclear components, and inservice inspection of nuclear reactor coolant systems. In the years following this, the scope of ASME nuclear codes, standards and guides has been broadened significantly to include air cleaning activities for nuclear power reactors, operation and maintenance of nuclear power plants, quality assurance programs, cranes for nuclear facilities, qualification of mechanical equipment, and concrete reactor vessels and containments. ASME focuses on globalization of its codes, standards and guides by encouraging and promoting their use in the international community and by actively seeking participation of international members on its technical and supervisory committees and in accreditation activities. Details are provided on current international representation. Initiatives are underway to separate the technical requirements from administrative and enforcement requirements, to convert to hard metric units, to provide for non-U. S. materials, and to provide for translations into non-English languages. ASME activity as an accredited ISO 9000 registrar for suppliers of mechanical equipment is described. Rules are being developed for construction of containment systems for nuclear spent fuel and high-level waste transport packagings. Intensive

  14. cASM: Obtaining the Ability to Capture Requirements Information Across the Installation Contracting Support Community

    Science.gov (United States)

    2016-04-22

    social impact to the local populace, but this effect must be closely tied to the strategic effects desired.19 An ill planned acquisition could lead to...21 EVALUATION – CONTINGENCY ACQUISTION SUPPORT MODEL (cASM...iv LIST OF FIGURES Figure 1: Top Twenty Contingency Acquisition Expenditures by PSC…………….……….18 Figure 2: Evaluation of cASM

  15. Acid Sphingomyelinase (ASM is a Negative Regulator of Regulatory T Cell (Treg Development

    Directory of Open Access Journals (Sweden)

    Yuetao Zhou

    2016-08-01

    Full Text Available Background/Aims: Regulatory T cell (Treg is required for the maintenance of tolerance to various tissue antigens and to protect the host from autoimmune disorders. However, Treg may, indirectly, support cancer progression and bacterial infections. Therefore, a balance of Treg function is pivotal for adequate immune responses. Acid sphingomyelinase (ASM is a rate limiting enzyme involved in the production of ceramide by breaking down sphingomyelin. Previous studies in T-cells have suggested that ASM is involved in CD28 signalling, T lymphocyte granule secretion, degranulation, and vesicle shedding similar to the formation of phosphatidylserine-exposing microparticles from glial cells. However, whether ASM affects the development of Treg has not yet been described. Methods: Splenocytes, isolated Naive T lymphocytes and cultured T cells were characterized for various immune T cell markers by flow cytometery. Cell proliferation was measured by Carboxyfluorescein succinimidyl ester (CFSE dye, cell cycle analysis by Propidium Iodide (PI, mRNA transcripts by q-RT PCR and protein expression by Western Blotting respectively. Results: ASM deficient mice have higher number of Treg compared with littermate control mice. In vitro induction of ASM deficient T cells in the presence of TGF-β and IL-2 lead to a significantly higher number of Foxp3+ induced Treg (iTreg compared with control T-cells. Further, ASM deficient iTreg has less AKT (serine 473 phosphorylation and Rictor levels compared with control iTreg. Ceramide C6 led to significant reduction of iTreg in both ASM deficient and WT mice. The reduction in iTreg leads to induction of IL-1β, IL-6 and IL-17 but not IFN-γ mRNA levels. Conclusion: ASM is a negative regulator of natural and iTreg.

  16. Acid Sphingomyelinase (ASM) is a Negative Regulator of Regulatory T Cell (Treg) Development.

    Science.gov (United States)

    Zhou, Yuetao; Salker, Madhuri S; Walker, Britta; Münzer, Patrick; Borst, Oliver; Gawaz, Meinrad; Gulbins, Erich; Singh, Yogesh; Lang, Florian

    2016-01-01

    Regulatory T cell (Treg) is required for the maintenance of tolerance to various tissue antigens and to protect the host from autoimmune disorders. However, Treg may, indirectly, support cancer progression and bacterial infections. Therefore, a balance of Treg function is pivotal for adequate immune responses. Acid sphingomyelinase (ASM) is a rate limiting enzyme involved in the production of ceramide by breaking down sphingomyelin. Previous studies in T-cells have suggested that ASM is involved in CD28 signalling, T lymphocyte granule secretion, degranulation, and vesicle shedding similar to the formation of phosphatidylserine-exposing microparticles from glial cells. However, whether ASM affects the development of Treg has not yet been described. Splenocytes, isolated Naive T lymphocytes and cultured T cells were characterized for various immune T cell markers by flow cytometery. Cell proliferation was measured by Carboxyfluorescein succinimidyl ester (CFSE) dye, cell cycle analysis by Propidium Iodide (PI), mRNA transcripts by q-RT PCR and protein expression by Western Blotting respectively. ASM deficient mice have higher number of Treg compared with littermate control mice. In vitro induction of ASM deficient T cells in the presence of TGF-β and IL-2 lead to a significantly higher number of Foxp3+ induced Treg (iTreg) compared with control T-cells. Further, ASM deficient iTreg has less AKT (serine 473) phosphorylation and Rictor levels compared with control iTreg. Ceramide C6 led to significant reduction of iTreg in both ASM deficient and WT mice. The reduction in iTreg leads to induction of IL-1β, IL-6 and IL-17 but not IFN-γ mRNA levels. ASM is a negative regulator of natural and iTreg. © 2016 The Author(s) Published by S. Karger AG, Basel.

  17. Inhibition of allergen-induced basophil activation by ASM-024, a nicotinic receptor ligand.

    Science.gov (United States)

    Watson, Brittany M; Oliveria, John Paul; Nusca, Graeme M; Smith, Steven G; Beaudin, Sue; Dua, Benny; Watson, Rick M; Assayag, Evelynne Israël; Cormier, Yvon F; Sehmi, Roma; Gauvreau, Gail M

    2014-01-01

    Nicotinic acetylcholine receptors (nAChRs) were identified on eosinophils and shown to regulate inflammatory responses, but nAChR expression on basophils has not been explored yet. We investigated surface receptor expression of nAChR α4, α7 and α1/α3/α5 subunits on basophils. Furthermore, we examined the effects of ASM-024, a synthetic nicotinic ligand, on in vitro anti-IgE and in vivo allergen-induced basophil activation. Basophils were enriched from the peripheral blood of allergic donors and the expression of nAChR subunits and muscarinic receptors was determined. Purified basophils were stimulated with anti-IgE in the presence of ASM-024 with or without muscarinic or nicotinic antagonists for the measurement of CD203c expression and histamine release. The effect of 9 days of treatment with 50 and 200 mg ASM-024 on basophil CD203c expression was examined in the blood of mild allergic asthmatics before and after allergen inhalation challenge. nAChR α4, α7 and α1/α3/α5 receptor subunit expression was detected on basophils. Stimulation of basophils with anti-IgE increased CD203c expression and histamine release, which was inhibited by ASM-024 (10(-5) to 10(-)(3) M, p ASM-024 was reversed in the presence of muscarinic and nicotinic antagonists. In subjects with mild asthma, ASM-024 inhalation significantly inhibited basophil CD203c expression measured 24 h after allergen challenge (p = 0.03). This study shows that ASM-024 inhibits IgE- and allergen-induced basophil activation through both nicotinic and muscarinic receptors, and suggests that ASM-024 may be an efficacious agent for modulating allergic asthma responses. © 2015 S. Karger AG, Basel.

  18. Revision of the ASME nuclear quality assurance standard and its historical background

    International Nuclear Information System (INIS)

    Suzuki, Tetsuya

    2009-01-01

    ASME NQA-1-2008 'Quality Assurance Requirements for Nuclear Facility Applications' will be endorsed by US NRC by the end of 2009. This standard will apply to design, construction and operation of nuclear power plants newly erected in USA. It is important to Japanese vendors developing nuclear business in USA. Historical background, significance of revision and main revised points of the ASME nuclear quality assurance standard are described in the present paper. (T. Tanaka)

  19. Application procedures and analysis examples of the SIE ASME-NH program

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Seok Hoon; Koo, G. H.; Kim, J. B. [KAERI, Daejeon (Korea, Republic of)

    2010-12-15

    In this report, the design rule of the ASME-NH Code was briefly summarized and the application procedures of SIE ASME-NH program were analysed, the analysis examples were described. The SIE ASME-NH program was developed according to the ASME Code Section III Subsection NH rules to perform the primary stress limits, the accumulated inelastic strain limits and the creep fatigue damage evaluations in the structural design of nuclear power plants operating with high temperatures over creep temperature at normal operating conditions. In the analysis examples, the benchmark problem for the high temperature reactor vessel which was discussed in the SIE ASME-NH user's seminar was described. Also, the preliminary structural analysis of an Advanced Burner Test Reactor internal structure was described. Considering the load combinations of the various cycle types submitted from significant operating conditions, the integrity of a reactor internal structure was reviewed according to the stress and strain limits of the ASME-NH rules and the analysis and evaluation results were summarized

  20. Application procedures and analysis examples of the SIE ASME-NH program

    International Nuclear Information System (INIS)

    Kim, Seok Hoon; Koo, G. H.; Kim, J. B.

    2010-12-01

    In this report, the design rule of the ASME-NH Code was briefly summarized and the application procedures of SIE ASME-NH program were analysed, the analysis examples were described. The SIE ASME-NH program was developed according to the ASME Code Section III Subsection NH rules to perform the primary stress limits, the accumulated inelastic strain limits and the creep fatigue damage evaluations in the structural design of nuclear power plants operating with high temperatures over creep temperature at normal operating conditions. In the analysis examples, the benchmark problem for the high temperature reactor vessel which was discussed in the SIE ASME-NH user's seminar was described. Also, the preliminary structural analysis of an Advanced Burner Test Reactor internal structure was described. Considering the load combinations of the various cycle types submitted from significant operating conditions, the integrity of a reactor internal structure was reviewed according to the stress and strain limits of the ASME-NH rules and the analysis and evaluation results were summarized

  1. A Minimal Path Searching Approach for Active Shape Model (ASM)-based Segmentation of the Lung.

    Science.gov (United States)

    Guo, Shengwen; Fei, Baowei

    2009-03-27

    We are developing a minimal path searching method for active shape model (ASM)-based segmentation for detection of lung boundaries on digital radiographs. With the conventional ASM method, the position and shape parameters of the model points are iteratively refined and the target points are updated by the least Mahalanobis distance criterion. We propose an improved searching strategy that extends the searching points in a fan-shape region instead of along the normal direction. A minimal path (MP) deformable model is applied to drive the searching procedure. A statistical shape prior model is incorporated into the segmentation. In order to keep the smoothness of the shape, a smooth constraint is employed to the deformable model. To quantitatively assess the ASM-MP segmentation, we compare the automatic segmentation with manual segmentation for 72 lung digitized radiographs. The distance error between the ASM-MP and manual segmentation is 1.75 ± 0.33 pixels, while the error is 1.99 ± 0.45 pixels for the ASM. Our results demonstrate that our ASM-MP method can accurately segment the lung on digital radiographs.

  2. Chapter 8: Youth Culture

    DEFF Research Database (Denmark)

    Stald, Gitte Bang

    2016-01-01

    no longer has to be fixed, and can be negotiated. The discussion at the end of the chapter focuses on how technology changes at an increasing pace, and how its adoption changes the way we live and interact. Mobile phone use influences interpersonal and group dynamics, from the smallest unit of society......Gitte Stald has been researching mobile technologies since their early days of adoption by younger audiences. In her talk, she focuses on adolescents and their mobile media use. Stald shares her findings from the longitudinal and cross-cultural studies she has been conducting over the years....... The chapter builds on findings from a Danish and a European context, but they can be expanded to think about mobile youth culture in general. Gitte Stald discusses the concepts of digital natives and digital immigrants, sharing, immediacy, and the feeling of presence (or absent presence), social coordination...

  3. Chapter 8. Morphology: Verbs

    OpenAIRE

    Nesset, Tore

    2015-01-01

    Numerous exceptions and idiosyncrasies make the verb a major challenge in Modern Russian. Why are present tense forms inflected for first, second and third person, while past tense forms are inflected for masculine, feminine and neuter gender? Where do all the consonant alternations in verbs come from? Why is the particle бы used to form subjunctive constructions? You will find answers to these and many other questions in this chapter, which explores all the verb forms in Old Rusian, and expl...

  4. Equilíbrio corporal em crianças e adolescentes asmáticos e não asmáticos

    Directory of Open Access Journals (Sweden)

    Marta Cristina Rodrigues da Silva

    2013-06-01

    Full Text Available O objetivo foi analisar e comparar o equilíbrio corporal em crianças e adolescentes asmáticos e não asmáticos. Fizeram parte do grupo de estudos 24 sujeitos com idades de 7 a 14 anos divididos em dois grupos: grupo asmático e grupo controle. Para avaliação do equilíbrio corporal utilizou-se uma plataforma de força. Foram utilizadas as condições, olhos abertos e fechados com três tentativas aleatórias, com duração de 30 segundos cada uma. Os resultados apontaram diferença significativa entre os grupos, no teste de equilíbrio com olhos abertos apresentando maior amplitude de deslocamento na direção ântero-posterior (COPap (p = 0,04, e médio lateral (COPml (p = 0,02 no grupo asmático. Enquanto que no teste com olhos fechados a diferença foi significante apenas na amplitude de deslocamento ântero-posterior (COPap (p = 0,02 e Área de Elipse (p=0,03. Desse modo, a asma com suas limitações e consequências parece influenciar negativamente no equilíbrio corporal de seus portadores quando comparados com crianças sem a patologia e da mesma faixa etária.

  5. Being a Creative and an Immigrant in Montreal

    Directory of Open Access Journals (Sweden)

    Diane-Gabrielle Tremblay

    2016-09-01

    Full Text Available Work on creative careers has focused on the main national populations, while little research has addressed the situation of artists and creators of immigrant origin or different ethnic groups to determine whether they have the same access to work and employment rights. To respond for a call for research on different ethnic groups in the cultural sector, or the ethnic consequences of the individualization of careers, we therefore undertook research on the creative careers of immigrants in Montreal. We were interested in how they emerged as an artist, how they developed their careers, the access and rights they have in terms of support to their career, as McRobbie seems to indicate that ethnicity adds its “own weight to the life chances of those who are attempting to make a living in these fields. We found that these immigrant artists consider their main difficulties to be the lack of social networks, access to various forms of support to compensate for financial risks and difficulties in finding a job. We conclude with a few suggestions: measures to facilitate networking for immigrants, more training and information on government programs, mentoring support, as well as the support from community organizations, associations, and programs.

  6. [Rape by 2 assaillants and gang rape in Montreal].

    Science.gov (United States)

    Lamontagne, Y; Boyer, R; Lamontagne, C; Giroux, J

    1984-11-01

    A survey was conducted in 230 cases of rape and rape attempts heard in the Judicial District of Montreal between January 1975 and May 1978. Data were compiled from the 30 assaults including two or more assaillants. Results show that in cases of rape committed by two men the aggressors are older than gang rapists, meet the victim mainly in her flat or in a bar, and rape her in her own home, in a car or a hotel. In these cases, voyeurism seems to be an important factor since, most of the time, rape is committed by only one of the two aggressors. On the other hand, gang rapists are younger, meet the victim in public places, on the street or when she is hitch-hiking and attack her in one of the aggressors' house, in public places or on the street. Exhibitionism seems more present in this group of rapists. For both groups the victims are mainly single, younger than the aggressors and have diverse occupations. Finally, regarding the legal outcome half of the subjects were liberated or acquitted in both groups. Rape committed by two men had never been studied or compared with gang rape up until now. Results of this survey show dynamic and demographic differences between these two groups of sexual delinquents.

  7. Growing Physics and Astronomy Public Outreach in Montreal

    Science.gov (United States)

    Simard, Gabrielle; Lepo, Kelly

    2017-01-01

    AstroMcGill was founded in 2011 by an enthusiastic group of undergraduate students, graduate students and post-doctoral fellows. It serves as the education and public outreach (EPO) branch of the astronomy group within the Physics Department at McGill University in Montreal, Quebec. Over the last five years, AstroMcGill has grown from organizing sporadic visits in a couple primary schools to running a successful inquiry-based outreach programme for grade 4-6 students, the McGill Space Explorers. During the same time span, the attendance at public AstroNight lectures ramped up from attracting a few dozen people to over 500 people each month. We will highlight the recent successes of the programme and our best guesses for the reasons behind this success. We will also discuss the challenges of working in a bilingual city as we juggle our majority anglophone volunteers, a mandatory french science curriculum for primary school children and the (somewhat) overlapping English- and French-speaking communities in the city.

  8. 46 CFR 56.01-5 - Adoption of ASME B31.1 for power piping, and other standards.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Adoption of ASME B31.1 for power piping, and other... ENGINEERING PIPING SYSTEMS AND APPURTENANCES General § 56.01-5 Adoption of ASME B31.1 for power piping, and... accordance with ASME B31.1 (incorporated by reference; see 46 CFR 56.01-2), as limited, modified, or replaced...

  9. ASME code considerations for the compact heat exchanger

    Energy Technology Data Exchange (ETDEWEB)

    Nestell, James [MPR Associates Inc., Alexandria, VA (United States); Sham, Sam [Oak Ridge National Lab. (ORNL), Oak Ridge, TN (United States)

    2015-08-31

    robustness. Classic shell and tube designs will be large and costly, and may only be appropriate in steam generator service in the SHX where boiling inside the tubes occurs. For other energy conversion systems, all of these features can be met in a compact heat exchanger design. This report will examine some of the ASME Code issues that will need to be addressed to allow use of a Code-qualified compact heat exchanger in IHX or SHX nuclear service. Most effort will focus on the IHX, since the safety-related (Class A) design rules are more extensive than those for important-to-safety (Class B) or commercial rules that are relevant to the SHX.

  10. Quality Management. Chapter 19

    International Nuclear Information System (INIS)

    Hiles, P.A.; McLean, I.D.; Christofides, S.

    2014-01-01

    This chapter introduces the principles and definitions of quality management systems (QMSs) for radiology facilities, to give a framework to assist in the setting up of such systems and to emphasize the role of the medical physicist in this context. While there is a diversity of terms currently in use to describe quality processes both generally and specifically within radiology, there is broad agreement that the effective management of radiation medicine services demands a quality culture that includes a systematic approach to the elements that govern the delivery of that service. Therefore, the concept of quality assurance (QA) within the radiological facility covers, in its widest sense, all those factors that affect the intended outcome, that is, a clinical diagnosis. The medical physicist has an important role in the overall QMS, especially, but not exclusively, with respect to the equipment performance. A worked example of a quality control (QC) programme is included at the end of the chapter, to demonstrate the depth of detail and involvement of the medical physicist

  11. Roles of the Outer Membrane Protein AsmA of Salmonella enterica in the Control of marRAB Expression and Invasion of Epithelial Cells▿

    OpenAIRE

    Prieto, Ana I.; Hernández, Sara B.; Cota, Ignacio; Pucciarelli, M. Graciela; Orlov, Yuri; Ramos-Morales, Francisco; García-del Portillo, Francisco; Casadesús, Josep

    2009-01-01

    A genetic screen for suppressors of bile sensitivity in DNA adenine methylase (dam) mutants of Salmonella enterica serovar Typhimurium yielded insertions in an uncharacterized locus homologous to the Escherichia coli asmA gene. Disruption of asmA suppressed bile sensitivity also in phoP and wec mutants of S. enterica and increased the MIC of sodium deoxycholate for the parental strain ATCC 14028. Increased levels of marA mRNA were found in asmA, asmA dam, asmA phoP, and asmA wec strains of S....

  12. Science of Casting and Solidification: ASM Handbook Contributions — Honoring Professor Doru Michael Stefanescu

    Science.gov (United States)

    Lupulescu, Afina; Henry, Scott; Marken, Karen; Lampman, Steven

    Many of the metal casting processes are still empirical in nature. Many others are deeply rooted in mathematics and therefore, suitable for modeling. Science of casting and solidification is a major technical asset for foundry operations and of extreme importance in understanding different length scales microstructural changes and evolution as well as developing new processes and materials. In his attempt to describe combinations of solidification theory, research results and industrial practice, Professor Doru Michael Stefanescu (ASM Fellow, 1997) has made tremendous contributions to the field. Many of his views on casting and solidification are valued as important impacts within professional environments such as TMS and ASM International. He has written many articles for the ASM Handbook series on subjects including basic metallurgy of cast iron, compacted graphite irons, solidification, thermodynamic properties of iron-base alloys, and computational modeling. He was also Volume Chair for Volume 15: Casting, of the 9th Edition Metals Handbook.

  13. Basic requirements of mechanical properties for nuclear pressure vessel materials in ASME-BPV code

    International Nuclear Information System (INIS)

    Ning Dong; Yao Weida

    2011-01-01

    The four basic aspects of strengths, ductility, toughness and fatigue strengths can be summarized for overall mechanical properties requirements of materials for nuclear pressure-retaining vessels in ASME-BPV code. These mechanical property indexes involve in the factors of melting, manufacture, delivery conditions, check or recheck for mechanical properties and chemical compositions, etc. and relate to degradation and damage accumulation during the use of materials. This paper specifically accounts for the basic requirements and theoretic basis of mechanical properties for nuclear pressure vessel materials in ASME-BPV code and states the internal mutual relationships among the four aspects of mechanical properties. This paper focuses on putting forward at several problems on mechanical properties of materials that shall be concerned about during design and manufacture for nuclear pressure vessels according to ASME-BPV code. (author)

  14. Corticosteroids reduce IL-6 in ASM cells via up-regulation of MKP-1.

    Science.gov (United States)

    Quante, Timo; Ng, Yee Ching; Ramsay, Emma E; Henness, Sheridan; Allen, Jodi C; Parmentier, Johannes; Ge, Qi; Ammit, Alaina J

    2008-08-01

    The mechanisms by which corticosteroids reduce airway inflammation are not completely understood. Traditionally, corticosteroids were thought to inhibit cytokines exclusively at the transcriptional level. Our recent evidence, obtained in airway smooth muscle (ASM), no longer supports this view. We have found that corticosteroids do not act at the transcriptional level to reduce TNF-alpha-induced IL-6 gene expression. Rather, corticosteroids inhibit TNF-alpha-induced IL-6 secretion by reducing the stability of the IL-6 mRNA transcript. TNF-alpha-induced IL-6 mRNA decays at a significantly faster rate in ASM cells pretreated with the corticosteroid dexamethasone (t(1/2) = 2.4 h), compared to vehicle (t(1/2) = 9.0 h; P ASM cells.

  15. Cyclin D1 in ASM Cells from Asthmatics Is Insensitive to Corticosteroid Inhibition.

    Science.gov (United States)

    Allen, Jodi C; Seidel, Petra; Schlosser, Tobias; Ramsay, Emma E; Ge, Qi; Ammit, Alaina J

    2012-01-01

    Hyperplasia of airway smooth muscle (ASM) is a feature of the remodelled airway in asthmatics. We examined the antiproliferative effectiveness of the corticosteroid dexamethasone on expression of the key regulator of G(1) cell cycle progression-cyclin D1-in ASM cells from nonasthmatics and asthmatics stimulated with the mitogen platelet-derived growth factor BB. While cyclin D1 mRNA and protein expression were repressed in cells from nonasthmatics in contrast, cyclin D1 expression in asthmatics was resistant to inhibition by dexamethasone. This was independent of a repressive effect on glucocorticoid receptor translocation. Our results corroborate evidence demonstrating that corticosteroids inhibit mitogen-induced proliferation only in ASM cells from subjects without asthma and suggest that there are corticosteroid-insensitive proliferative pathways in asthmatics.

  16. Palaeoclimate. Chapter 6

    International Nuclear Information System (INIS)

    Jansen, E.; Overpeck, J.; Briffa, K.R.; Duplessy, J.C.; Joos, F.; Masson-Delmotte, V.; Olago, D.; Otto-Bliesner, B.; Peltier, W.R.; Rahmstorf, S.; Ramesh, R.; Raynaud, D.; Rind, D.; Solomina, O.; Villalba, R.; Zhang, D.

    2007-01-01

    This chapter assesses palaeoclimatic data and knowledge of how the climate system changes over interannual to millennial time scales, and how well these variations can be simulated with climate models. Additional palaeoclimatic perspectives are included in other chapters. Palaeoclimate science has made significant advances since the 1970s, when a primary focus was on the origin of the ice ages, the possibility of an imminent future ice age, and the first explorations of the so-called Little Ice Age and Medieval Warm Period. Even in the first IPCC assessment, many climatic variations prior to the instrumental record were not that well known or understood. Fifteen years later, understanding is much improved, more quantitative and better integrated with respect to observations and modelling. After a brief overview of palaeoclimatic methods, including their strengths and weaknesses, this chapter examines the palaeoclimatic record in chronological order, from oldest to youngest. This approach was selected because the climate system varies and changes over all time scales, and it is instructive to understand the contributions that lower-frequency patterns of climate change might make in influencing higher-frequency patterns of variability and change. In addition, an examination of how the climate system has responded to large changes in climate forcing in the past is useful in assessing how the same climate system might respond to the large anticipated forcing changes in the future. Cutting across this chronologically based presentation are assessments of climate forcing and response, and of the ability of state-of-the-art climate models to simulate the responses. Perspectives from palaeoclimatic observations, theory and modelling are integrated wherever possible to reduce uncertainty in the assessment. Several sections also assess the latest developments in the rapidly advancing area of abrupt climate change, that is, forced or unforced climatic change that involves

  17. CHAPTER 1. Introduction

    KAUST Repository

    Zhang, Lianbin

    2016-02-23

    With the development of modern industry and modern economies, environmental problems, especially water pollution and water scarcity, have become the most serious global challenges. In dealing with these challenges, various kinds of functionalized materials and devices are purposefully developed, fabricated, and utilized. It is clear that smart materials have not only provided effective strategies for solving environmental problems, but have also exhibited unprecedented advantages over traditional materials by integrating multifunctions and/or processes into one advanced device/material. In this book, we will present a broad collection of bioinspired smart materials and systems that are used in environmental problem solving. The topics of these chapters span from bioinspired fog collection, self-healing materials, responsive particle-stabilized emulsions, smart draw solutions in forward osmosis, slippery coating, insightful analysis of problems and opportunities for hydrophobic surfaces applied in real conditions, to superwetting materials for oil-water separation.

  18. Tailored ceramics. Chapter 5

    International Nuclear Information System (INIS)

    Haker, A.B.

    1988-01-01

    In the light of the broad variation in US high-level waste (HLW) types and the uncertainties in future waste production, research on the Rockwell International Science Center has focussed on developing a generic technology for the consolidation of high-level wastes into polyphase ceramics. The basic approach has been to 'tailor' wste compositions with chemical additives so that upon consolidation a dense ceramic assemblage is formed that chemically binds the waste species into known phases. This chapter deals with tailored ceramics for current and future high-level waste compositions. Section 2 gives a historical review of the development of tailored ceramics. Section 3 deals with tailored ceramics designed for specific HLW compositions and with microstructure and phase development. Section 4 discusses chemical and physical properties of tailored ceramic waste forms. In section 5 the various processing steps involved in converting HLW to polycrystalline ceramic forms are described. (author). 159 refs.; 20 figs.; 14 tabs

  19. Chapter No.2. Legislation

    International Nuclear Information System (INIS)

    2002-01-01

    UJD as the central body of state administration prepares legislation within their competency and sets also binding criteria in the field of nuclear safety. Based on provisions of the 'Atomic Act' the preparation of rest regulations has continued. Following drafts of 5 were prepared regulations in 2001 and then they were sent for comments to various ministries by UJD: (a) Regulation on safety requirements for design of nuclear installations; (b) Regulation on safety requirements for commissioning and operation of nuclear installations; (c) Regulation on safety documentation; (d) Regulation on periodic safety assessment; (e) Regulation on safety requirements for siting of nuclear installations. Two following UJD safety guides were published in 2001 as the part of edition 'Safety of Nuclear Installations': (a) BNS I. 11.2/1999 'Requirements for performance of safety analyses for ATWS' (b) BNS II.3.1/2000 'Evaluation of acceptability of faults detected during the operation inspection of nuclear installation selected equipment'. As UJD is responsible for performance of such reviews according to law No. 264/1999 Coll. on conformance assessment of products about 10 drafts of technical standards were reviewed. UJD provided documentation to the Slovak Republic position document related to Chapter 14 - Energy which was submitted to the European Union (EU). The set of recommendations related to nuclear safety was elaborated by the special working group on atomic question which was established by the EU Council. Their implementation is required as a prerequisite to close negotiations on Chapter 14 - Energy. The schedule of necessary safety related measures was agreed in co-operation with the SE a.s. and the Ministry of Economy and submitted as additional information for negotiations to the EC. The negotiations on Chapter 14 - Energy were successfully closed in October 2001. The activities in the area of Chapter 22 - Environment were concentrated on submission of necessary data

  20. ASME and RCC-MR comparison for the prevention of fatigue analysis

    International Nuclear Information System (INIS)

    Autrusson, B.; Acker, D.

    1989-01-01

    The purpose of this survey is to compare the simplified methods, without reference to the safety factor allowed for the mechanical properties. An application of both codes, RCC-MR and ASME, on the design of the wall mock-up of the NET project is made and also an estimation with an elastoplastic analysis. In the case of fatigue analysis according to ASME in the plastic field, the elastic stress is magnified by a K e factor derived from stress variation, S n , disregarding geometrical discontinuities. According to RCC-MR, the elastic maximum strain will magnified by two coefficients accounting for plasticity and variation of Poisson ratio

  1. A Survey of Variable Extragalactic Sources with XTE's All Sky Monitor (ASM)

    Science.gov (United States)

    Jernigan, Garrett

    1998-01-01

    The original goal of the project was the near real-time detection of AGN utilizing the SSC 3 of the ASM on XTE which does a deep integration on one 100 square degree region of the sky. While the SSC never performed sufficiently well to allow the success of this goal, the work on the project has led to the development of a new analysis method for coded aperture systems which has now been applied to ASM data for mapping regions near clusters of galaxies such as the Perseus Cluster and the Coma Cluster. Publications are in preparation that describe both the new method and the results from mapping clusters of galaxies.

  2. ASM LabCap's contributions to disease surveillance and the International Health Regulations (2005).

    Science.gov (United States)

    Specter, Steven; Schuermann, Lily; Hakiruwizera, Celestin; Sow, Mah-Séré Keita

    2010-12-03

    The revised International Health Regulations [IHR(2005)], which requires the Member States of the World Health Organization (WHO) to develop core capacities to detect, assess, report, and respond to public health threats, is bringing new challenges for national and international surveillance systems. As more countries move toward implementation and/or strengthening of their infectious disease surveillance programs, the strengthening of clinical microbiology laboratories becomes increasingly important because they serve as the first line responders to detect new and emerging microbial threats, re-emerging infectious diseases, the spread of antibiotic resistance, and the possibility of bioterrorism. In fact, IHR(2005) Core Capacity #8, "Laboratory", requires that laboratory services be a part of every phase of alert and response.Public health laboratories in many resource-constrained countries require financial and technical assistance to build their capacity. In recognition of this, in 2006, the American Society for Microbiology (ASM) established an International Laboratory Capacity Building Program, LabCap, housed under the ASM International Board. ASM LabCap utilizes ASM's vast resources and its membership's expertise-40,000 microbiologists worldwide-to strengthen clinical and public health laboratory systems in low and low-middle income countries. ASM LabCap's program activities align with HR(2005) by building the capability of resource-constrained countries to develop quality-assured, laboratory-based information which is critical to disease surveillance and the rapid detection of disease outbreaks, whether they stem from natural, deliberate or accidental causes.ASM LabCap helps build laboratory capacity under a cooperative agreement with the U.S. Centers for Disease Control and Prevention (CDC) and under a sub-contract with the Program for Appropriate Technology in Health (PATH) funded by the United States Agency for International Development (USAID

  3. 46 CFR 52.01-2 - Adoption of section I of the ASME Boiler and Pressure Vessel Code.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Adoption of section I of the ASME Boiler and Pressure... and Pressure Vessel Code. (a) Main power boilers and auxiliary boilers shall be designed, constructed, inspected, tested, and stamped in accordance with section I of the ASME Boiler and Pressure Vessel Code...

  4. 46 CFR 53.01-3 - Adoption of section IV of the ASME Boiler and Pressure Vessel Code.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 2 2010-10-01 2010-10-01 false Adoption of section IV of the ASME Boiler and Pressure... Boiler and Pressure Vessel Code. (a) Heating boilers shall be designed, constructed, inspected, tested, and stamped in accordance with section IV of the ASME Boiler and Pressure Vessel Code (incorporated by...

  5. Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency.

    Science.gov (United States)

    Acuña, Mariana; Castro-Fernández, Víctor; Latorre, Mauricio; Castro, Juan; Schuchman, Edward H; Guixé, Victoria; González, Mauricio; Zanlungo, Silvana

    2016-10-21

    Niemann-Pick disease (NPD) type A and B are recessive hereditary disorders caused by deficiency in acid sphingomyelinase (ASM). The p.Ala359Asp mutation has been described in several patients but its functional and structural effects in the protein are unknown. In order to characterize this mutation, we modeled the three-dimensional ASM structure using the recent available crystal of the mammalian ASM as a template. We found that the p.Ala359Asp mutation is localized in the hydrophobic core and far from the sphingomyelin binding site. However, energy function calculations using statistical potentials indicate that the mutation causes a decrease in ASM stability. Therefore, we investigated the functional effect of the p.Ala359Asp mutation in ASM expression, secretion, localization and activity in human fibroblasts. We found a 3.8% residual ASM activity compared to the wild-type enzyme, without changes in the other parameters evaluated. These results support the hypothesis that the p.Ala359Asp mutation causes structural alterations in the hydrophobic environment where ASM is located, decreasing its enzymatic activity. A similar effect was observed in other previously described NPDB mutations located outside the active site of the enzyme. This work shows the first full size ASM mutant model describe at date, providing a complete analysis of the structural and functional effects of the p.Ala359Asp mutation over the stability and activity of the enzyme. Copyright © 2016 Elsevier Inc. All rights reserved.

  6. The 1997 NRC IST workshops and the status of questions and issues directed to the ASME O and M committee

    International Nuclear Information System (INIS)

    DiBiasio, A.M.

    1998-05-01

    This paper describes the results of the four NRC Inservice Testing (IST) Workshops which were held in early 1997 pertaining to NRC Inspection Procedure P 73756, Inservice Testing of Pumps and Valves. It also presents the status of the ASME code committees' resolution of certain questions forwarded to the ASME by the NRC. These questions relate to code interpretations, inconsistencies in the code, and industry concerns that are most appropriately resolved through the ASME consensus process. The ASME committees reviewed the questions at their December 1997 and March 1998 code meetings. Of particular interest are those questions for which the ASME code committees did not agree with the NRC response. These questions, as well as those which the committees provided some additional insight or input, are presented in this paper

  7. Climate change impacts on pollinic productivity and allergic rhinitis in Montreal between 1994 and 2002

    Energy Technology Data Exchange (ETDEWEB)

    Garneau, M.; Breton, M.; Fortier, I. [Quebec Univ., Montreal, PQ (Canada)

    2005-07-01

    This presentation defined the correlation between pollinic concentrations of ragweed and medical consultations for allergic rhinitis in Montreal between 1994 and 2002, taking into account meteorological variables and socio-economic factors. The spatio-temporal dynamic of pollinic, meteorological, socio-economic and epidemiological values was reconstituted from descriptive, geographical and statistical analyses. Throughout the ragweed pollinic seasons (August to October) between 1994 and 2002 in the Montreal island area, there were 7,138 consultations for allergic rhinitis. The study concluded that the lengthening of the pollinic seasons, as well as the increase in the average number of medical consultations, combined with the significant correlation linking the temperature to pollinic concentrations suggests that the population affected by pollen allergies will increase over the coming decades in Montreal, and that it will affect certain areas more than others, which is consistent with the anticipated impacts of the rise in temperatures forecasted by different models of climate scenarios.

  8. SUSTAINABILITY ASSESSMENT IN URBAN PLANNING. A CHALLENGE FOR A METHODOLOGICAL CONSTRUCTION: MONTREAL AS CASE STUDY

    Directory of Open Access Journals (Sweden)

    María de Lourdes Flores Lucero

    2014-09-01

    Full Text Available In this paper we describe the methodological process for the qualitative evaluation of the concept of sustainability and its application in the island of Montreal. At the same time we present our theoretical approach and the main results issued of the assessment. We take as analytical tools the Montreal Urban Plan of 2004 and the Strategic Plan for Sustainable Development 2005. We conclude with two main points, first, that the theoretical and pragmatic aspects of urban sustainability in Montreal have been treated in an organic, complex, dynamic and flexible way, allowing social participation and the inclusion of the values of all stakeholders, which are both key elements to follow the path towards sustainability; and secondly, that the approach to an object with such features requires the construction of complex, organic and methodological processes.

  9. Career development through local chapter involvement: perspectives from chapter members.

    Science.gov (United States)

    Thomas, Melissa; Inniss-Richter, Zipporah; Mata, Holly; Cottrell, Randall R

    2013-07-01

    The importance of career development in professional organizations has been noted in the literature. Personal and professional benefits of membership regardless of discipline can be found across the career spectrum from student to executive. The benefits of professional membership with respect to career development in local chapter organizations have seldom been studied. Local chapter participation may offer significant career development opportunities for the practitioner, faculty member, and student. The purpose of this study was to explore the importance of local chapter involvement to the career development of health education practitioners. An 18-item questionnaire was disseminated to the membership of three local SOPHE (Society for Public Health Education) chapters that explored the level of local chapter involvement and the impact of how specific professional development activities impacted career development. The results of the survey highlighted the importance of continuing education programs, networking, and leadership experience in developing one's career that are offered by local SOPHE chapter involvement. Making a positive impact in the community and earning the respect of one's peers were most often reported as indicators of career success. These factors can directly impact local chapter participation. Career development can certainly be enhanced by active participation in the local chapter of a professional association.

  10. The Montreal Protocol treaty and its illuminating history of science-policy decision-making

    Science.gov (United States)

    Grady, C.

    2017-12-01

    The Montreal Protocol on Substances that Deplete the Ozone Layer, hailed as one of the most effective environmental treaties of all time, has a thirty year history of science-policy decision-making. The partnership between Parties to the Montreal Protocol and its technical assessment panels serve as a basis for understanding successes and evaluating stumbles of global environmental decision-making. Real-world environmental treaty negotiations can be highly time-sensitive, politically motivated, and resource constrained thus scientists and policymakers alike are often unable to confront the uncertainties associated with the multitude of choices. The science-policy relationship built within the framework of the Montreal Protocol has helped constrain uncertainty and inform policy decisions but has also highlighted the limitations of the use of scientific understanding in political decision-making. This talk will describe the evolution of the scientist-policymaker relationship over the history of the Montreal Protocol. Examples will illustrate how the Montreal Protocol's technical panels inform decisions of the country governments and will characterize different approaches pursued by different countries with a particular focus on the recently adopted Kigali Amendment. In addition, this talk will take a deeper dive with an analysis of the historic technical panel assessments on estimating financial resources necessary to enable compliance to the Montreal Protocol compared to the political financial decisions made through the Protocol's Multilateral Fund replenishment negotiation process. Finally, this talk will describe the useful lessons and challenges from these interactions and how they may be applicable in other environmental management frameworks across multiple scales under changing climatic conditions.

  11. Roles of the outer membrane protein AsmA of Salmonella enterica in the control of marRAB expression and invasion of epithelial cells.

    Science.gov (United States)

    Prieto, Ana I; Hernández, Sara B; Cota, Ignacio; Pucciarelli, M Graciela; Orlov, Yuri; Ramos-Morales, Francisco; García-del Portillo, Francisco; Casadesús, Josep

    2009-06-01

    A genetic screen for suppressors of bile sensitivity in DNA adenine methylase (dam) mutants of Salmonella enterica serovar Typhimurium yielded insertions in an uncharacterized locus homologous to the Escherichia coli asmA gene. Disruption of asmA suppressed bile sensitivity also in phoP and wec mutants of S. enterica and increased the MIC of sodium deoxycholate for the parental strain ATCC 14028. Increased levels of marA mRNA were found in asmA, asmA dam, asmA phoP, and asmA wec strains of S. enterica, suggesting that lack of AsmA activates expression of the marRAB operon. Hence, asmA mutations may enhance bile resistance by inducing gene expression changes in the marRAB-controlled Mar regulon. In silico analysis of AsmA structure predicted the existence of one transmembrane domain. Biochemical analysis of subcellular fractions revealed that the asmA gene of S. enterica encodes a protein of approximately 70 kDa located in the outer membrane. Because AsmA is unrelated to known transport and/or efflux systems, we propose that activation of marRAB in asmA mutants may be a consequence of envelope reorganization. Competitive infection of BALB/c mice with asmA(+) and asmA isogenic strains indicated that lack of AsmA attenuates Salmonella virulence by the oral route but not by the intraperitoneal route. Furthermore, asmA mutants showed a reduced ability to invade epithelial cells in vitro.

  12. Chapter 11. Heat Exchangers

    Energy Technology Data Exchange (ETDEWEB)

    Rafferty, Kevin D.; Culver, Gene

    1998-01-01

    Most geothermal fluids, because of their elevated temperature, contain a variety of dissolved chemicals. These chemicals are frequently corrosive toward standard materials of construction. As a result, it is advisable in most cases to isolate the geothermal fluid from the process to which heat is being transferred. The task of heat transfer from the geothermal fluid to a closed process loop is most often handled by a plate heat exchanger. The two most common types used in geothermal applications are: bolted and brazed. For smaller systems, in geothermal resource areas of a specific character, downhole heat exchangers (DHEs) provide a unique means of heat extraction. These devices eliminate the requirement for physical removal of fluid from the well. For this reason, DHE-based systems avoid entirely the environmental and practical problems associated with fluid disposal. Shell and tube heat exchangers play only a minor role in low-temperature, direct-use systems. These units have been in common use in industrial applications for many years and, as a result, are well understood. For these reasons, shell and tube heat exchangers will not be covered in this chapter.

  13. Xenobiotics: Chapter 15

    Science.gov (United States)

    Bridges, Christine M.; Semlitsch, Raymond D.; Lannoo, Michael

    2005-01-01

    While a number of compounds have been reported as toxic to amphibians, until recently, there have been conspicuously few ecotoxicological studies concerning amphibians. Studies are now focusing on the effects of xenobiotics on amphibians, an interest likely stimulated by widespread reports of amphibian declines. It has been speculated that chemical contamination may be partially to blame for some documented amphibian declines, by disrupting growth, reproduction, and behavior. However, evidence that xenobiotics are directly to blame for population declines is sparse because environmental concentrations are typically not great enough to generate direct mortality. Although the effects of environmental contaminants on the amphibian immune system are currently unknown, it is possible that exposure to stressors such as organic pollutants (which enter ecosystems in the form of pesticides) may depress immune system function, thus allowing greater susceptibility to fungal infections. This chapter discusses toxicity testing for xenobiotics and presents the results of a study that has focused on the subtle effects of sublethal concentrations of the chemical carbaryl on tadpoles.

  14. Towards the next chapter

    CERN Multimedia

    2013-01-01

    In the late 1970s, while the CERN community was busy preparing the SPS to operate as a collider and planning for LEP, people also had their eyes on the next chapter in the unfolding story of CERN.   That the LEP tunnel should be built with a future hadron collider in mind was a given by the end of the decade. But there had also been proposals to build large proton storage rings, or re-equip the ISR with superconducting magnets. Some people had suggested building an electron-proton collider at CERN, and there were ambitious plans looking far into the future at a possible Very Big Accelerator to be built somewhere in the world, which went by its acronym VBA. For the field of particle physics, with its very long lead times, this is part of the normal cycle, and while most of those options never came to fruition, this process did pave the way for the LHC. Today, with the LHC programme underway, the time has come for CERN to start seriously considering the options for its post-LHC future. Perhaps ...

  15. Synthesis: Chapter 19

    Science.gov (United States)

    Pardo, L.H.; Geiser, L.H.; Fenn, M.E.; Driscoll, C.T.; Goodale, C.L.; Allen, E.B.; Baron, Jill S.; Bobbink, R.; Bowman, W.D.; Clark, C.M.; Emmett, B.; Gilliam, F.S.; Greaver, T.; Hall, S.J.; Lilleskov, E.A.; Liu, L.; Lynch, J.A.; Nadelhoffer, K.; Perakis, S.S.; Robin-Abbott, M. J.; Stoddard, J.L.; Weathers, K. C.

    2011-01-01

    Human activity in the last century has led to a substantial increase in nitrogen (N) emissions and deposition (Galloway et al. 2003). Because of past, and, in some regions, continuing increases in emissions (Lehmann et al. 2005, Nilles and Conley 2001), this N deposition has reached a level that has caused or is likely to cause alterations and damage in many ecosystems across the United States. In some ecoregions, the impact of N deposition has been severe and has changed the biotic community structure and composition of ecosystems. In the Mediterranean California ecoregion, for example (see Chapter 13), replacement of native by exotic invasive vegetation is accelerated because exotic species are often more productive under elevated N deposition than native species in some California grasslands, coastal sage scrub, and desert scrub (Fenn et al. 2010, Rao and Allen 2010, Rao et al. 2010, Weiss 1999, Yoshida and Allen 2004). Such shifts in plant community composition and species richness can have consequences beyond changes in ecosystem structure: shifts may lead to overall losses in biodiversity and further impair particular threatened or endangered species (Stevens et al. 2004). Th e extirpation of the endangered checkerspot butterfl y (Euphydryas editha bayensis), because the host plant for the larval stage disappears in N-enriched ecosystems (Fenn et al. 2010, Weiss 1999), is just one example of the detrimental impacts of elevated N deposition.

  16. Researching on knowledge architecture of design by analysis based on ASME code

    International Nuclear Information System (INIS)

    Bao Shiyi; Zhou Yu; He Shuyan

    2003-01-01

    The quality of knowledge-based system's knowledge architecture is one of decisive factors of knowledge-based system's validity and rationality. For designing the ASME code knowledge based system, this paper presents a knowledge acquisition method which is extracting knowledge through document analysis consulted domain experts' knowledge. Then the paper describes knowledge architecture of design by analysis based on the related rules in ASME code. The knowledge of the knowledge architecture is divided into two categories: one is empirical knowledge, and another is ASME code knowledge. Applied as the basement of the knowledge architecture, a general procedural process of design by analysis that is met the engineering design requirements and designers' conventional mode is generalized and explained detailed in the paper. For the sake of improving inference efficiency and concurrent computation of KBS, a kind of knowledge Petri net (KPN) model is proposed and adopted in expressing the knowledge architecture. Furthermore, for validating and verifying of the empirical rules, five knowledge validation and verification theorems are given in the paper. Moreover the research production is applicable to design the knowledge architecture of ASME codes or other engineering standards. (author)

  17. Impact of ACI-ASME code on design and construction of nuclear containment structures

    International Nuclear Information System (INIS)

    Reedy, R.F.

    1978-01-01

    The effect of the ACI-ASME code for design and construction of concrete containment structures on the nuclear and concrete industries is examined. Topics covered include purpose of the code, general requirements, responsibilities and duties, design and construction specifications, quality assurance, inspection, the liner, and stamping

  18. SDZ ASM 981: an emerging safe and effective treatment for atopic dermatitis.

    NARCIS (Netherlands)

    Luger, T.; Leent, E.J. van; Graeber, M.; Hedgecock, S.; Thurston, M.; Kandra, A.; Berth-Jones, J.; Bjerke, J.; Christophers, E.; Knop, J.; Knulst, A.C.; Morren, M.; Morris, A.; Reitamo, S.; Roed-Petersen, J.; Schoepf, E.; Thestrup-Pedersen, K.; Valk, P.G.M. van der; Bos, J.D.

    2001-01-01

    BACKGROUND: SDZ ASM 981 is a selective inhibitor of the production of pro-inflammatory cytokines from T cells and mast cells in vitro. It is the first ascomycin macrolactam derivative under development for the treatment of inflammatory skin diseases. OBJECTIVES: This study was designed to determine

  19. Parameter subset selection for the dynamic calibration of activated sludge models (ASMs): experience versus systems analysis

    DEFF Research Database (Denmark)

    Ruano, MV; Ribes, J; de Pauw, DJW

    2007-01-01

    In this work we address the issue of parameter subset selection within the scope of activated sludge model calibration. To this end, we evaluate two approaches: (i) systems analysis and (ii) experience-based approach. The evaluation has been carried out using a dynamic model (ASM2d) calibrated...

  20. Technical justification for ASME code section xi crack detection by visual examination

    International Nuclear Information System (INIS)

    Nickell, R.E.; Rashid, Y.R.

    2001-01-01

    A critical technical element of nuclear power plant license renewal in the United States is the demonstration that the effects of aging do not compromise the intended safety function(s) of a system, structure, or component during the extended term of operation. The demonstration may take either of two forms. First, it can be shown that the design basis for the system, structure, or component is sufficiently robust that the aging effects have been insignificant through the current license term, and will continue to be insignificant through the extended term. Alternatively, it can be shown that, while the aging effects may be potentially significant, those effects can be managed and functionality maintained by defined programmatic activities during the extended term of operation. The first of the two approaches is generally provided by the construction basis, such as construction in accordance with the ASME Code Section III and other consensus codes and standards. The second of the two approaches is often provided by periodic inservice inspection and testing, in accordance with the ASME Code Section XI. The purpose of the ASME Section XI inspections and tests is to assure that systems, components, and structures are fit for continued service until the next scheduled inspection or test. The purpose of this paper is to document the effectiveness of the current ASME Code Section XI visual examination procedures in detecting the effects of aging for systems, structures, and components that are tolerant of mature cracks. (author)

  1. Reaction invariant-based reduction of the activated sludge model ASM1 for batch applications

    DEFF Research Database (Denmark)

    Santa Cruz, Judith A.; Mussati, Sergio F.; Scenna, Nicolás J.

    2016-01-01

    to batch activated sludge processes described by the Activated Sludge Model No. 1 (ASM1) for carbon and nitrogen removal. The objective of the model reduction is to describe the exact dynamics of the states predicted by the original model with a lower number of ODEs. This leads to a reduction...

  2. SDZ ASM 981: an emerging safe and effective treatment for atopic dermatitis

    NARCIS (Netherlands)

    Luger, T.; van Leent, E. J.; Graeber, M.; Hedgecock, S.; Thurston, M.; Kandra, A.; Berth-Jones, J.; Bjerke, J.; Christophers, E.; Knop, J.; Knulst, A. C.; Morren, M.; Morris, A.; Reitamo, S.; Roed-Petersen, J.; Schoepf, E.; Thestrup-Pedersen, K.; van der Valk, P. G.; Bos, J. D.

    2001-01-01

    SDZ ASM 981 is a selective inhibitor of the production of pro-inflammatory cytokines from T cells and mast cells in vitro. It is the first ascomycin macrolactam derivative under development for the treatment of inflammatory skin diseases. This study was designed to determine the safety and efficacy

  3. SDZ ASM 981: an emerging safe and effective treatment for atopic dermatitis

    NARCIS (Netherlands)

    Luger, T; Van Leent, EJM; Graeber, M; Hedgecock, S; Thurston, M; Kandra, A; Berth-Jones, J; Bjerke, J; Christophers, E; Knulst, AC; Morren, M; Morris, A; Reitamo, S; Roed-Petersen, J; Schoepf, E; Thestrup-Pedersen, K; van der Valk, P. G. M.; Bos, JD

    Background SDZ ASM 981 is a selective inhibitor of the production of pro-inflammatory cytokines from T cells and mast cells in vitro. It is the first ascomycin macrolactam derivative under development for the treatment of inflammatory skin diseases. Objectives This study was: designed to determine

  4. Simulation and optimization of a coking wastewater biological treatment process by activated sludge models (ASM).

    Science.gov (United States)

    Wu, Xiaohui; Yang, Yang; Wu, Gaoming; Mao, Juan; Zhou, Tao

    2016-01-01

    Applications of activated sludge models (ASM) in simulating industrial biological wastewater treatment plants (WWTPs) are still difficult due to refractory and complex components in influents as well as diversity in activated sludges. In this study, an ASM3 modeling study was conducted to simulate and optimize a practical coking wastewater treatment plant (CWTP). First, respirometric characterizations of the coking wastewater and CWTP biomasses were conducted to determine the specific kinetic and stoichiometric model parameters for the consecutive aeration-anoxic-aeration (O-A/O) biological process. All ASM3 parameters have been further estimated and calibrated, through cross validation by the model dynamic simulation procedure. Consequently, an ASM3 model was successfully established to accurately simulate the CWTP performances in removing COD and NH4-N. An optimized CWTP operation condition could be proposed reducing the operation cost from 6.2 to 5.5 €/m(3) wastewater. This study is expected to provide a useful reference for mathematic simulations of practical industrial WWTPs. Copyright © 2015 Elsevier Ltd. All rights reserved.

  5. Technical report on comparative analysis of ASME QA requirements and ISO series

    International Nuclear Information System (INIS)

    Kim, Kwan Hyun

    2000-06-01

    This technical report provides the differences on the QA requirement ASME and ISO in nuclear fields. This report applies to the quality assurance(QA) programmes of the design of two requirement. The organization having overall responsibility for the nuclear design, preservation, fabrication shall be described in this report in each stage of design project

  6. ASM LabCap’s contributions to disease surveillance and the International Health Regulations (2005

    Directory of Open Access Journals (Sweden)

    Hakiruwizera Celestin

    2010-12-01

    Full Text Available Abstract The revised International Health Regulations [IHR(2005], which requires the Member States of the World Health Organization (WHO to develop core capacities to detect, assess, report, and respond to public health threats, is bringing new challenges for national and international surveillance systems. As more countries move toward implementation and/or strengthening of their infectious disease surveillance programs, the strengthening of clinical microbiology laboratories becomes increasingly important because they serve as the first line responders to detect new and emerging microbial threats, re-emerging infectious diseases, the spread of antibiotic resistance, and the possibility of bioterrorism. In fact, IHR(2005 Core Capacity #8, “Laboratory”, requires that laboratory services be a part of every phase of alert and response. Public health laboratories in many resource-constrained countries require financial and technical assistance to build their capacity. In recognition of this, in 2006, the American Society for Microbiology (ASM established an International Laboratory Capacity Building Program, LabCap, housed under the ASM International Board. ASM LabCap utilizes ASM’s vast resources and its membership’s expertise—40,000 microbiologists worldwide—to strengthen clinical and public health laboratory systems in low and low-middle income countries. ASM LabCap’s program activities align with HR(2005 by building the capability of resource-constrained countries to develop quality-assured, laboratory-based information which is critical to disease surveillance and the rapid detection of disease outbreaks, whether they stem from natural, deliberate or accidental causes. ASM LabCap helps build laboratory capacity under a cooperative agreement with the U.S. Centers for Disease Control and Prevention (CDC and under a sub-contract with the Program for Appropriate Technology in Health (PATH funded by the United States Agency for

  7. 77 FR 12909 - Eastern Maine Railway Company-Assignment of Trackage Rights Exemption-Montreal, Maine & Atlantic...

    Science.gov (United States)

    2012-03-02

    ... Surface Transportation Board Eastern Maine Railway Company--Assignment of Trackage Rights Exemption--Montreal, Maine & Atlantic Railway, Ltd. and Maine Northern Railway Company Pursuant to a written agreement, Montreal, Maine & Atlantic Railway, Ltd. (MMA) has agreed to assign its overhead trackage rights to the...

  8. 76 FR 32266 - Maine Northern Railway Company-Trackage Rights Exemption-Montreal, Maine & Atlantic Railway, Ltd.

    Science.gov (United States)

    2011-06-03

    ... Surface Transportation Board Maine Northern Railway Company--Trackage Rights Exemption-- Montreal, Maine & Atlantic Railway, Ltd. Pursuant to a written trackage rights agreement, Montreal, Maine & Atlantic Railway, Ltd. (MMA) has agreed to grant overhead trackage rights to the Maine Northern Railway Company (MNRC...

  9. Interpreting ASME limits and philosophy in FEA of pressure vessel parts

    International Nuclear Information System (INIS)

    Bezerra, L.M.; Cruz, J.R.B.; Miranda, C.A.J.; Neto, M.M.

    1995-01-01

    In recent years there has been an effort to interpret finite element (FE) stress results on the light of the ASME B and PV rules and philosophy. Many task groups have issued guidelines on stress linearization and classifications. All those attempts have come up trying to cope modern FE techniques with the rules imposed by the ASME Code. This paper is an independent contribution to the Pressure Vessel Research Council (PVRC) groups which are studying the stress classification and the failure mechanism in a FE framework. This work tries to complement the interesting work by Hollinger and Hechmer presented in the PVP-94 in Minneapolis. In that paper, the authors examined a typical support skirt and showed relations between the skirt collapse load obtained by finite element analysis and the loads allowed from the ASME stress limits. To complement such paper, in the present article, different skirt geometry configurations are analyzed. The configurations here investigated consist of similar support skirts but with different angles of attachments between cylinder and cone parts. It will be possible to observe the influence of the bending stress in the collapse load and its relation to the allowable loads inferred from the ASME limits. A pressure vessel with torispherical head under internal pressure is also examined. Using elastic and limit load FEA, the present paper determines the collapse loads of the configurations. It sets up the relations between these collapse loads, stress categories, and limits dictated by the ASME Code Subsection NB. On the light of NB rules and philosophy, this paper shows how different methods of stress assessment, classification, and limits may influence in the design of a pressure vessel

  10. Statistical analysis of geomagnetic field intensity differences between ASM and VFM instruments onboard Swarm constellation

    Science.gov (United States)

    De Michelis, Paola; Tozzi, Roberta; Consolini, Giuseppe

    2017-02-01

    From the very first measurements made by the magnetometers onboard Swarm satellites launched by European Space Agency (ESA) in late 2013, it emerged a discrepancy between scalar and vector measurements. An accurate analysis of this phenomenon brought to build an empirical model of the disturbance, highly correlated with the Sun incidence angle, and to correct vector data accordingly. The empirical model adopted by ESA results in a significant decrease in the amplitude of the disturbance affecting VFM measurements so greatly improving the vector magnetic data quality. This study is focused on the characterization of the difference between magnetic field intensity measured by the absolute scalar magnetometer (ASM) and that reconstructed using the vector field magnetometer (VFM) installed on Swarm constellation. Applying empirical mode decomposition method, we find the intrinsic mode functions (IMFs) associated with ASM-VFM total intensity differences obtained with data both uncorrected and corrected for the disturbance correlated with the Sun incidence angle. Surprisingly, no differences are found in the nature of the IMFs embedded in the analyzed signals, being these IMFs characterized by the same dominant periodicities before and after correction. The effect of correction manifests in the decrease in the energy associated with some IMFs contributing to corrected data. Some IMFs identified by analyzing the ASM-VFM intensity discrepancy are characterized by the same dominant periodicities of those obtained by analyzing the temperature fluctuations of the VFM electronic unit. Thus, the disturbance correlated with the Sun incidence angle could be still present in the corrected magnetic data. Furthermore, the ASM-VFM total intensity difference and the VFM electronic unit temperature display a maximal shared information with a time delay that depends on local time. Taken together, these findings may help to relate the features of the observed VFM-ASM total intensity

  11. Chapter 3. Legislation

    International Nuclear Information System (INIS)

    2001-01-01

    The Nuclear Regulatory Authority of the Slovak Republic (UJD) as the central authority of state administration prepares legislation within their competency and sets also binding criteria in the field of nuclear safety. Based on provisions of the 'Atomic Act' a preparation of remaining 8 decrees have continued. In 2000 the following decrees were issued by UJD: (1) Decree No. 31/2000 Coll on events at nuclear installations. It came into force on 15 February 2000. (2) Decree No. 190/2000 Coll by which details of radioactive waste management and spent fuel management are regulated. It came into force on 1-st July 2000. The following six decrees are at the process of preparation: (a) Decree on quality assurance of nuclear installations, (b) Decree on safety requirements for design of nuclear installations, (c) Decree on safety requirements for commissioning and operation of nuclear installations, (d) Decree on safety documentation, (e) Decree on periodic safety assessment, (f) Decree on safety requirements for siting of nuclear installations. Following five UJD safety guides were published in 2000 as the part of edition 'Safety of Nuclear Installations': (1) BNS I.9.1/1999 Safety of nuclear facilities during decommissioning (issued in April 2000). (2) BNS III.4.1/2000 Requirements on UJD SR permit issue for fuel use in WWER 440 reactors (issued in September 2000). (3) BNS III.4.3/2000 Requirements on assessment of fuel loading for WWER 440 reactors (issued in September 2000). (4) BNS I.2.6/2000 UJD SR requirements on chapter 4 of Safety analysis report 'Core design' (issued in September 2000). (5) NS I.4.2/1996 Use of PSA methodology in the process of regulation by regulatory authority (issued in September 2000). About thirty-five drafts of technical standards were reviewed as UJD is responsible for performance such review according to the law No. 264/1999 Coll. on conformance assessment of products. UJD provided necessary documentation for negotiation positions of the

  12. Collective Intelligence. Chapter 17

    Science.gov (United States)

    Wolpert, David H.

    2003-01-01

    Many systems of self-interested agents have an associated performance criterion that rates the dynamic behavior of the overall system. This chapter presents an introduction to the science of such systems. Formally, collectives are defined as any system having the following two characteristics: First, the system must contain one or more agents each of which we view as trying to maximize an associated private utility; second, the system must have an associated world utility function that rates the possible behaviors of that overall system. In practice, collectives are often very large, distributed, and support little, if any, centralized communication and control, although those characteristics are not part of their formal definition. A naturally occurring example of a collective is a human economy. One can identify the agents and their private utilities as the human individuals in the economy and the associated personal rewards they are each trying to maximize. One could then identify the world utility as the time average of the gross domestic product. ("World utility" per se is not a construction internal to a human economy, but rather something defined from the outside.) To achieve high world utility it is necessary to avoid having the agents work at cross-purposes lest phenomena like liquidity traps or the Tragedy of the Commons (TOC) occur, in which agents' individually pursuing their private utilities lowers world utility. The obvious way to avoid such phenomena is by modifying the agents utility functions to be "aligned" with the world utility. This can be done via punitive legislation. A real-world example of an attempt to do this was the creation of antitrust regulations designed to prevent monopolistic practices.

  13. Applicability of Montreal Process Criterion 1 - conservation of biological diversity - to rangeland sustainability

    Science.gov (United States)

    Curtis H. Flather; Carolyn Hull Sieg

    2000-01-01

    Nine indicators of biodiversity conservation have been defined by the nations participating in the Montreal Process for assessing sustainability of temperate and boreal forests. Five of these indicators address compositional and spatial diversity of ecosystems; two address species diversity; and two are indirect measures of genetic diversity. Our objective was to...

  14. Relocating Precarity and Resiliency within Montreal: The Artists' Bloc of the Immigrant Workers' Centre

    Science.gov (United States)

    Hall, Koby Rogers; Salamanca, Manuel

    2017-01-01

    In this document we describe our experience relocating precarity and resiliency by way of arts activism, to denounce and make visible social injustices experienced by im/migrant communities in Montreal. Under the umbrella of the Immigrant Workers' Centre, and other allies from the im/migrant workers' movement, we combine knowledge building, action…

  15. Sensitivity and Specificity of the Montreal Cognitive Assessment Modified for Individuals Who Are Visually Impaired

    Science.gov (United States)

    Wittich, Walter; Phillips, Natalie; Nasreddine, Ziad S.; Chertkow, Howard

    2010-01-01

    Evaluating the cognitive status of individuals who are visually impaired is limited by the design of the test that is used. This article presents data on the sensitivity and specificity of the version of the Montreal Cognitive Assessment for people who are visually impaired. The original validation data were reanalyzed, excluding the five visual…

  16. A feasibility study of conducting the Montreal Cognitive Assessment remotely in individuals with movement disorders.

    Science.gov (United States)

    Abdolahi, Amir; Bull, Michael T; Darwin, Kristin C; Venkataraman, Venayak; Grana, Matthew J; Dorsey, E Ray; Biglan, Kevin M

    2016-06-01

    Remote assessments of individuals with a neurological disease via telemedicine have the potential to reduce some of the burdens associated with clinical care and research participation. We aim to evaluate the feasibility of conducting the Montreal Cognitive Assessment remotely in individuals with movement disorders. A pilot study derived from two telemedicine trials was conducted. In total, 17 individuals with movement disorders (8 with Parkinson disease and 9 with Huntington disease) had Montreal Cognitive Assessment examinations evaluated in-person and remotely via web-based video conferencing to primarily determine feasibility and potential barriers in its remote administration. Administering the Montreal Cognitive Assessment remotely in a sample of movement disorder patients with mild cognitive impairment is feasible, with only minor common complications associated with technology, including delayed sound and corrupted imaging for participants with low connection speeds. The Montreal Cognitive Assessment has the potential to be used in remote assessments of patients and research participants with movement disorders. © The Author(s) 2014.

  17. American Red Cross Chapter Regions

    Data.gov (United States)

    Department of Homeland Security — The Regions are part of the national field level structure to support chapters. The Regions role is admistrative as well as provides oversight and program technical...

  18. Parametric study of emerging high power accelerator applications using Accelerator Systems Model (ASM)

    International Nuclear Information System (INIS)

    Berwald, D.H.; Mendelsohn, S.S.; Myers, T.J.; Paulson, C.C.; Peacock, M.A.; Piaszczyk, CM.; Rathke, J.W.; Piechowiak, E.M.

    1996-01-01

    Emerging applications for high power rf linacs include fusion materials testing, generation of intense spallation neutrons for neutron physics and materials studies, production of nuclear materials and destruction of nuclear waste. Each requires the selection of an optimal configuration and operating parameters for its accelerator, rf power system and other supporting subsystems. Because of the high cost associated with these facilities, economic considerations become paramount, dictating a full evaluation of the electrical and rf performance, system reliability/availability, and capital, operating, and life cycle costs. The Accelerator Systems Model (ASM), expanded and modified by Northrop Grumman during 1993-96, provides a unique capability for detailed layout and evaluation of a wide variety of normal and superconducting accelerator and rf power configurations. This paper will discuss the current capabilities of ASM, including the available models and data base, and types of trade studies that can be performed for the above applications. (author)

  19. Comparisons of ratchetting analysis methods using RCC-M, RCC-MR and ASME codes

    International Nuclear Information System (INIS)

    Yang Yu; Cabrillat, M.T.

    2005-01-01

    The present paper compares the simplified ratcheting analysis methods used in RCC-M, RCC-MR and ASME with some examples. Firstly, comparisons of the methods in RCC-M and efficiency diagram in RCC-MR are investigated. A special method is used to describe these two methods with curves in one coordinate, and the different conservation is demonstrated. RCC-M method is also be interpreted by SR (second ratio) and v (efficiency index) which is used in RCC-MR. Hence, we can easily compare the previous two methods by defining SR as abscissa and v as ordinate and plotting two curves of them. Secondly, comparisons of the efficiency curve in RCC-MR and methods in ASME-NH APPENDIX T are investigated, with significant creep. At last, two practical evaluations are performed to show the comparisons of aforementioned methods. (authors)

  20. Design and test of ASME strainer for primary cooling system in HANARO

    International Nuclear Information System (INIS)

    Park, Yong-Chul; Ryu, Jeong-Soo

    1999-01-01

    The ASME strainers have been newly installed at the suction side of each reactor coolant pump to get rid of the foreign materials which may damage the pump impeller or interfere with the coolant path of fuel flow tube or primary plate type heat exchanger. The strainer was designed in accordance with ASME SEC. III, DIV. 1, ND and the structural integrity was verified by seismic analysis. The screen was designed in accordance with the effective void area from the result of flow analysis for T-type strainer. After installation of the strainer, it was confirmed through the field test that the flow characteristics of primary cooling system were not adversely affected. The pressure loss coefficient was calculated by Darcy equation using the pressure difference through each strainer and the flow rate measured during the strainer performance test. And these are useful data to predict flow variations by the pressure difference. (author)

  1. Extended activated sludge model no. 1 (ASM1 for simulating biodegradation process using bacterial technology

    Directory of Open Access Journals (Sweden)

    Ya-jing Song

    2012-09-01

    Full Text Available Phosphorus is one of the most important nutrients required to support various kinds of biodegradation processes. As this particular nutrient is not included in the activated sludge model no. 1 (ASM1, this study extended this model in order to determine the fate of phosphorus during the biodegradation processes. When some of the kinetics parameters are modified using observed data from the restoration project of the Xuxi River in Wuxi City, China, from August 25 to 31 in 2009, the extended model shows excellent results. In order to obtain optimum values of coefficients of nitrogen and phosphorus, the mass fraction method was used to ensure that the final results were reasonable and practically relevant. The temporal distribution of the data calculated with the extended ASM1 approximates that of the observed data.

  2. Appropriate nominal stresses for use with ASME Code pressure-loading stress indices for nozzles

    International Nuclear Information System (INIS)

    Rodabaugh, E.C.

    1976-06-01

    This program is part of a cooperative effort with industry to develop and verify analytical methods for assessing the safety of nuclear pressure-vessel and piping-system design. The study of nominal stresses and stress indices described is part of a continuing study of design rules for nozzles in pressure vessels being coordinated by the PVRC Subcommittee on Reinforced Openings and External Loadings. Results from these studies are used by appropriate ASME Code groups in drafting new and improved design rules

  3. The control of safety allowance for nuclear power plant components in ASME-BPVC

    International Nuclear Information System (INIS)

    Yao Weida; Ning Dong; Yang Ren'an; He Yinbiao; Xie Yongcheng; Zhang Ming; Yao Yangui

    2011-01-01

    How to control the 'safety allowance' reasonably at each phase of materials, design, fabrication, test, examination, building, pre-service and in-service operation and others in ASME-BPVC was preliminarily discussed. The two quantitative requirements of 'safety factor' and 'acceptance criteria' were dissected. The responsibilities of controlled documents and personnel to assure 'safety allowance' were also represented. (authors)

  4. Report on ANSI/ASME nuclear air and gas treatment standards for nuclear power plants

    International Nuclear Information System (INIS)

    Fish, J.F.

    1979-01-01

    Original N Committee, N45-8, has completed and published through the approved American National Standards Institute process two Standards, N-509 and N-510. This committee has been dissolved and replaced by ASME Committee on Nuclear Air and Gas Treatment with expanded scope to cover not only air cleaning, but thermal treatment equipment. Current efforts are directed to produce Code documents rather than Standards type publications. This report summarizes changed scope, current organization and sub-committee coverage areas

  5. Application of ASME code AG-1 to YGN 3 ampersand 4 plants, South Korea

    International Nuclear Information System (INIS)

    Kim, Y.K.; Porco, R.D.; York, Y.D.

    1993-01-01

    Yonggwang Nuclear Power Plant Units 3 ampersand 4 are located on the southwestern coast of South Korea on the Yellow Sea. The plant is owned by Korea Electric Power Corp. (KEPCO), with the engineering being performed by Korea Power Engineering Co., Inc. (KOPEC) and Sargent and Lundy under a technology transfer agreement. The plants are both 950 Megawatt (electric) pressurized water reactors of US design. Under contract to KEPCO, Korea Heavy Industries and Construction Co., Ltd. and Ellis and Watts, Division of Dynamics Corporation of America, Batavia, Ohio, supplied major components to the YGN plants in compliance to ASME AG-1. These components included safety related Air Cleaning Units, Reactor containment Fan Cooler Units, Air Handling Units, Cubicle Coolers, Duct Electric Heaters, and fans. This paper details the extent of applicability of ASME Code AG-1 to the specific equipment, description of the equipment, conformance, testing, and design required. The paper also discusses the problems encountered in implementing ASME AG-1, working around Code sections that were not complete at contract inception, conflicts in project documents and related problems. Also discussed are the logistics problems, material availability, and quality assurance aspects complicating the applications of ASME AG-1, due to the required Korean content for some components. Based on successfully supplying the equipment referenced above, it has been concluded that AG-1 is a working document and can be successfully implemented. It provides the requirements necessary for performance, design, construction, acceptance testing, and quality assurance of equipment used as components in nuclear air and gas treatment systems in nuclear facilities. The paper also addresses lessons learned and aspects of mixing US design and US built components in Korean built assemblies

  6. Meeting report on the ASM Conference on Mechanisms of Interbacterial Cooperation and Competition.

    Science.gov (United States)

    Lories, Bram; Parijs, Ilse; Foster, Kevin R; Steenackers, Hans P

    2017-08-14

    The ASM Conference on Mechanisms of Interbacterial Cooperation and Competition was held in Washington DC, from 1 to 4 March 2017. The conference provided an international forum for sociomicrobiologists from different disciplines to present and discuss new findings. The meeting covered a wide range of topics, spanning molecular mechanisms, ecology, evolution, computation and manipulation of interbacterial interactions, and encompassed social communities in medicine, the natural environment, and industry. This report summarizes the presentations and emerging themes. Copyright © 2017 American Society for Microbiology.

  7. The intracarotid amobarbital procedure (Wada test with two protocols combined, Montreal and Seattle Procedimentos do amobarbital intracarotideo (teste de Wada com dois protocolos combinados, Montreal e Seattle

    Directory of Open Access Journals (Sweden)

    Paulo J. M. Leite

    1997-06-01

    Full Text Available The intracarotid amobarbital procedure was carried out in 8 male and 7 female candidates to temporal lobectomy, and a female candidate to frontal lesionectomy, aged 18-50 (mean 32.5 years. Language and memory were tested after injection in each hemisphere. Both were measured by the Montreal procedure. In 9 patients language and memory were evaluated with the Seattle procedure too. In 12 patients the left hemisphere was dominant for language; three had bilateral dominance. In I patient the Seattle procedure demonstrated the dominant hemisphere by relatively slowness of speech during the drug effect in the left hemisphere. Memory was defined to be in the left hemisphere in 12 patients, in the right in 2, bilateral in 1 and in another lateralization was not possible. In 1 patient memory dominance was determined by the Montreal protocol alone because of lack of cooperation. These early results indicate that the methods may be complementary for determination of language and memory dominance in epilepsy surgery candidates.O testo do amobarbital intracarotídeo foi realizado em 8 homens e 7 mulheres candidatos a lobectomia temporal e em uma mulher candidata a lesionectomia frontal, com idades de 18-50 (média 32,5 anos. Linguagem e memória foram testadas após a injeção do amobarbial em cada hemisfério cerebral. Todos os pacientes foram avaliados pelo método de Montreal e 9 também pelo método de Seattle. Em 12 pacientes o hemisfério cerebral esquerdo foi dominante para linguagem e em 3 pacientes houve dominância bilateral. Em uma paciente a linguagem foi determinada apenas através do método de Seattle, com lentificação relativa da fal a, sob ação da droga no hemisfério cerebral esquerdo. Dominância da memória à esquerda foi observada em 12 pacientes, à direita em 2, bilateral em 1 e em outro não foi lateralizada. Dominância da memória foi definida apenas através do método de Montreal em um paciente, devido à pouca coopera

  8. RXTE ASM Observations of GRB991216 - A One Hour Old X-ray Afterglow

    Science.gov (United States)

    Corbet, R.; Smith, D. A.

    The Gamma-ray Burst 991216 (the ``Beethoven" burst) was both very bright itself and also had an unusually bright X-ray afterglow. This afterglow was observed and localized by the RXTE PCA 4 hours after the burst occurred (Takeshima et al. 1999). This position determination then enabled an optical afterglow to be found (Uglesich et al 1999). Serendipitously, the RXTE ASM obtained a sequence of 7 observations covering this source in a period of 11 minutes starting just 1 hour after the burst peak. From these 7 dwells, a flux of 32 +/- 8 mCrabs (1 sigma error) was determined which is consistent with a power-law extrapolation of RXTE PCA flux measurements. While GRB afterglows are generally faint and thus difficult for the RXTE ASM to study, due to its modest collecting area and short observation times, we believe that this unusually bright afterglow has indeed been detected. These results indicate that the RXTE ASM has provided a measurement of an X-ray afterglow light curve at times which have previously not been studied.

  9. Modification of the ASME code z-factor for circumferential surface crack in nuclear ferritic pipings

    International Nuclear Information System (INIS)

    Choi, Young Hwan; Chung, Yon Ki; Koh, Wan Young; Lee, Joung Bae

    1996-01-01

    The purpose of this paper is to modify the ASME Code Z-Factor, which is used in the evaluation of circumferential surface crack in nuclear ferritic pipings. The ASME Code Z-Factor is a load multiplier to compensate plastic load with elasto-plastic load. The current ASME Code Z-Factor underestimates pipe maximum load. In this study, the original SC. TNP method is modified first because the original SC. TNP method has a problem that the maximum allowable load predicted from the original SC. TNP method is slightly higher than that measured from the experiment. Then the new Z-Factor is developed using the modified SC. TNP method. The desirability of both the modified SC. TNP method and the new Z-Factor is examined using the experimental results for the circumferential surface crack in pipings. The results show that (1) the modified SC. TNP method is good for predicting the circumferential surface crack behavior in pipings, and (2) the Z-Factor obtained from the modified SC. TNP method well predicts the behavior of circumferential surface crack in ferritic pipings. 30 refs., 13 figs., 4 tabs. (author)

  10. Linearization of the activated sludge model ASM1 for fast and reliable predictions.

    Science.gov (United States)

    Smets, Ilse Y; Haegebaert, Jeroen V; Carrette, Ronald; Van Impe, Jan F

    2003-04-01

    In this paper a strategy is proposed to reduce the complexity of the activated sludge model no. 1 (ASM1) which describes the biotransformation processes in a common activated sludge process with N-removal. The key feature of the obtained reduced model is that it combines high predictive value (all state variables keep their biological interpretation) with very low computation time. Therefore, this model is a valuable tool in a risk assessment environment (designed for the evaluation of wastewater treatment plants facing stricter effluent norms) as well as in on-line (MPC) control strategies. The complexity reduction procedure consists of four steps. In the first step representative input/output data sets are generated by simulating the full ASM1 model. In the second step the ASM1 model is rewritten in state space format with linear approximations of the nonlinear (kinetic) terms. In the third step the unknown parameters in the linear terms are identified based on the generated input/output data. To reduce the amount of parameter sets that have to be identified (to cover the full operation range of the plant), a Multi-Model interpolation procedure is introduced as a last step.

  11. Comparison of SKIFS 2004:1 and Tillsynshandbok PSA against the ASME PRA Standard and European requirements on PSA; Jaemfoerelse av SKIFS 2004:1 och Tillsynshandbok PSA mot ASME PRA Standard och Europeiska krav paa PSA

    Energy Technology Data Exchange (ETDEWEB)

    Hellstroem, Per

    2005-04-15

    Requirements on PSA for risk informed applications are expressed in different international documents. The ASME PRA standard published in spring 2002 is one such document, PSA requirements are also expressed in the European Utility Requirements (EUR) for new reactors. The Swedish PSA requirements are provided in the Swedish regulators (SKI) statutes SKIFS 2004:1. SKI also has a review handbook for PSA activities (SKI report 2003:48). The review handbook is a support during review of the utilities PSA activities and the PSAs themselves. The review handbook expresses SKIs expectations by providing so called important aspects for both the PSA work and the PSAs, A comparison of SKIFS requirements and the important aspects in the Review handbook, on one side, and the requirements on PSA in EUR and ASME on the other side, is presented. The comparison shows a large difference in the level of detail in the different documents, where ASME is most detailed and specific. This is expected since the SKI review handbook not is a 'PSA guide' in the same way as the ASME PRA standard. A direct comparison of the ASME PRA standard requirements with the important aspects in the review handbook cannot answer the question which ASME capacity level that is achieved by a PSA meeting all important aspects. The conclusion is that it is not likely to achieve capacity level 2 and 3, since very few ASME level 3 attributes are explicitly expressed as important aspects, though many are expressed in general terms. The review handbook important aspects that are most similar to the ASME capacity level 1 attributes are initiating events, sequence analysis, and system analysis while less similarity is found for analysis of operator actions data analysis, quantification and containment analysis (level 2). Less similarity is found for capacity level 2 and 3. However, the number of additional ASME attributes on capacity level 2 and 3 are few. There are also important aspects in the review

  12. The precautionary principle as a provisional instrument in environmental policy: The Montreal Protocol case study

    International Nuclear Information System (INIS)

    Jacobs, J. Roger

    2014-01-01

    Highlights: • I examine whether a policy invoked under the Precautionary Principle can move beyond provisional status. • I review the certainty of conclusions based upon the Global Ozone Research and Monitoring Project. • There is high certainty that anthropogenic ozone depletion has health consequences in polar regions. • Current research focuses on long term projections of risk that perpetuates high uncertainty. • Establishment of a community to generate Assessments acts to perpetuate the period of uncertainty. - Abstract: Environmental studies identify possible threats to the health of the public or the environment when the scientific certainty of risk is low, but the potential cost is high. Governments may respond by invoking the Precautionary Principle, holding that scientific certainty is not required to take actions that reduce possible risk. EU guidelines suggest that precautionary measures remain provisional until sufficient scientific certainty is generated. Here I study the Scientific Assessments produced for the Montreal Protocol, and the scientific community that generates them, and ask whether a long-standing program of scientific investigation and monitoring can generate sufficient scientific certainty to move beyond dependence on the Precautionary Principle. When the Montreal Protocol was ratified, many scientists strongly suspected that anthropogenic substances like chlorofluorocarbons were depleting stratospheric ozone. Although the risk was uncertain, the perceived cost to public health of ozone depletion was high. A quarter century after formulating the Montreal Protocol, science can define the conditions for ozone depletion with great certainty, but uncertainty remains in determining the scale and distribution of the attributable increase in damaging ultra-violet (UV) radiation. Organisations, such as NASA, and scientists that contribute to the Scientific Assessments comprise the community in which the scientific consensus of risk is

  13. GC-ASM: Synergistic Integration of Graph-Cut and Active Shape Model Strategies for Medical Image Segmentation.

    Science.gov (United States)

    Chen, Xinjian; Udupa, Jayaram K; Alavi, Abass; Torigian, Drew A

    2013-05-01

    Image segmentation methods may be classified into two categories: purely image based and model based. Each of these two classes has its own advantages and disadvantages. In this paper, we propose a novel synergistic combination of the image based graph-cut (GC) method with the model based ASM method to arrive at the GC-ASM method for medical image segmentation. A multi-object GC cost function is proposed which effectively integrates the ASM shape information into the GC framework. The proposed method consists of two phases: model building and segmentation. In the model building phase, the ASM model is built and the parameters of the GC are estimated. The segmentation phase consists of two main steps: initialization (recognition) and delineation. For initialization, an automatic method is proposed which estimates the pose (translation, orientation, and scale) of the model, and obtains a rough segmentation result which also provides the shape information for the GC method. For delineation, an iterative GC-ASM algorithm is proposed which performs finer delineation based on the initialization results. The proposed methods are implemented to operate on 2D images and evaluated on clinical chest CT, abdominal CT, and foot MRI data sets. The results show the following: (a) An overall delineation accuracy of TPVF > 96%, FPVF segmentation step compared to GC which requires seed specification and improves on the accuracy of GC. (e) One disadvantage of GC-ASM is its increased computational expense owing to the iterative nature of the algorithm.

  14. Densidade Mineral Óssea em Mulheres Asmáticas, na Fase Perimenopausa

    Directory of Open Access Journals (Sweden)

    Anne K. Laatikainen

    1999-07-01

    Full Text Available RESUMO: Os corticóides inalados, constituem a terapêutica anti-inflamatória de eleição, utilizada nos asmáticos, por longos penodos.Para além dos corticóides inalados utilizados como terapêutica preventiva, a corticoterapia oral e endovenosa é por vezes necessária nos períodos de exacerbação da doença.É bem conhecido o risco de osteoporose em doentes com asma grave medicados com corticoterapta oral a longo prazo O efeito dos corticóides inalados a nivel da densidade óssea, não é bem conhecido, pelo que tem sido alvo de estudos recentes.A menopausa é considerada o principal factor de risco da osteoporose. Ainda não é bem conhecido qual o papel da asma como factor de risco de ostcoporose equal o impacto dos corticóides inalados na densitometria óssea.Os autores procederam a urn estudo inicialmente dingido a uma população de 14220 mulheres dos 47 aos 56 anos de idade (período perimenopausa, residentes na Província de Kuopio, no Leste da Finlândia.Foi enviado urn inquérito incluindo a história ginecológica, uso de terapêutica hormonal de substituição, paridade, peso, altura, actividade fisica, consumo de produtos lácteos, hábitos tabágicos, morbilidade e teraêuticas habituais. Houve resposta em 84 4% dos inquiridos.Foi realizada osteodensitometria óssea (BMD do colo do fémur esquerdo e coluna em 3222 mulheres, de acordo com um estudo randomizado simples, estratificado.Após exclusão de alguns registos considerados inválidos, a população estudada consistia em 2941 mulheres, das quais 119 eram asmáticas. A estas foi feito um inquérito adicional acerca do uso de cortticóides, dose diária, duração e regularidade.Os autores verificaram que 72 doentes (60.5% estavam medicadas com corticóides inalados. Dez asmáticas faziam regularmente corticoterapia oral. Em 61 doentes havia referência a pelo menos um curso de corticóide oral nos últimos 6 meses. Vinte e oito asmáticas nunca tinham feito terap

  15. Understanding the Long-Term Spectral Variability of Cygnus X-1 from BATSE and ASM Observations

    Science.gov (United States)

    Zdziarski, Andrzej A.; Poutanen, Juri; Paciesas, William S.; Wen, Linqing; Six, N. Frank (Technical Monitor)

    2002-01-01

    We present a spectral analysis of observations of Cygnus X-1 by the RXTE/ASM (1.5-12 keV) and CGRO/BATSE (20-300 keV), including about 1200 days of simultaneous data. We find a number of correlations between intensities and hardnesses in different energy bands from 1.5 keV to 300 keV. In the hard (low) spectral state, there is a negative correlation between the ASM 1.5-12 keV flux and the hardness at any energy. In the soft (high) spectral state, the ASM flux is positively correlated with the ASM hardness (as previously reported) but uncorrelated with the BATSE hardness. In both spectral states, the BATSE hardness correlates with the flux above 100 keV, while it shows no correlation with the flux in the 20-100 keV range. At the same time, there is clear correlation between the BATSE fluxes below and above 100 keV. In the hard state, most of the variability can be explained by softening the overall spectrum with a pivot at approximately 50 keV. The observations show that there has to be another, independent variability pattern of lower amplitude where the spectral shape does not change when the luminosity changes. In the soft state, the variability is mostly caused by a variable hard (Comptonized) spectral component of a constant shape superimposed on a constant soft blackbody component. These variability patterns are in agreement with the dependence of the rms variability on the photon energy in the two states. We interpret the observed correlations in terms of theoretical Comptonization models. In the hard state, the variability appears to be driven mostly by changing flux in seed photons Comptonized in a hot thermal plasma cloud with an approximately constant power supply. In the soft state, the variability is consistent with flares of hybrid, thermal/nonthermal, plasma with variable power above a stable cold disk. Also, based on broadband pointed observations simultaneous with those of the ASM and BATSE, we find the intrinsic bolometric luminosity increases by a

  16. ASM-3 acid sphingomyelinase functions as a positive regulator of the DAF-2/AGE-1 signaling pathway and serves as a novel anti-aging target.

    Directory of Open Access Journals (Sweden)

    Yongsoon Kim

    Full Text Available In C. elegans, the highly conserved DAF-2/insulin/insulin-like growth factor 1 receptor signaling (IIS pathway regulates longevity, metabolism, reproduction and development. In mammals, acid sphingomyelinase (ASM is an enzyme that hydrolyzes sphingomyelin to produce ceramide. ASM has been implicated in CD95 death receptor signaling under certain stress conditions. However, the involvement of ASM in growth factor receptor signaling under physiological conditions is not known. Here, we report that in vivo ASM functions as a positive regulator of the DAF-2/IIS pathway in C. elegans. We have shown that inactivation of asm-3 extends animal lifespan and promotes dauer arrest, an alternative developmental process. A significant cooperative effect on lifespan is observed between asm-3 deficiency and loss-of-function alleles of the age-1/PI 3-kinase, with the asm-3; age-1 double mutant animals having a mean lifespan 259% greater than that of the wild-type animals. The lifespan extension phenotypes caused by the loss of asm-3 are dependent on the functions of daf-16/FOXO and daf-18/PTEN. We have demonstrated that inactivation of asm-3 causes nuclear translocation of DAF-16::GFP protein, up-regulates endogenous DAF-16 protein levels and activates the downstream targeting genes of DAF-16. Together, our findings reveal a novel role of asm-3 in regulation of lifespan and diapause by modulating IIS pathway. Importantly, we have found that two drugs known to inhibit mammalian ASM activities, desipramine and clomipramine, markedly extend the lifespan of wild-type animals, in a manner similar to that achieved by genetic inactivation of the asm genes. Our studies illustrate a novel strategy of anti-aging by targeting ASM, which may potentially be extended to mammals.

  17. ASM-3 Acid Sphingomyelinase Functions as a Positive Regulator of the DAF-2/AGE-1 Signaling Pathway and Serves as a Novel Anti-Aging Target

    Science.gov (United States)

    Kim, Yongsoon; Sun, Hong

    2012-01-01

    In C. elegans, the highly conserved DAF-2/insulin/insulin-like growth factor 1 receptor signaling (IIS) pathway regulates longevity, metabolism, reproduction and development. In mammals, acid sphingomyelinase (ASM) is an enzyme that hydrolyzes sphingomyelin to produce ceramide. ASM has been implicated in CD95 death receptor signaling under certain stress conditions. However, the involvement of ASM in growth factor receptor signaling under physiological conditions is not known. Here, we report that in vivo ASM functions as a positive regulator of the DAF-2/IIS pathway in C. elegans. We have shown that inactivation of asm-3 extends animal lifespan and promotes dauer arrest, an alternative developmental process. A significant cooperative effect on lifespan is observed between asm-3 deficiency and loss-of-function alleles of the age-1/PI 3-kinase, with the asm-3; age-1 double mutant animals having a mean lifespan 259% greater than that of the wild-type animals. The lifespan extension phenotypes caused by the loss of asm-3 are dependent on the functions of daf-16/FOXO and daf-18/PTEN. We have demonstrated that inactivation of asm-3 causes nuclear translocation of DAF-16::GFP protein, up-regulates endogenous DAF-16 protein levels and activates the downstream targeting genes of DAF-16. Together, our findings reveal a novel role of asm-3 in regulation of lifespan and diapause by modulating IIS pathway. Importantly, we have found that two drugs known to inhibit mammalian ASM activities, desipramine and clomipramine, markedly extend the lifespan of wild-type animals, in a manner similar to that achieved by genetic inactivation of the asm genes. Our studies illustrate a novel strategy of anti-aging by targeting ASM, which may potentially be extended to mammals. PMID:23049887

  18. ASM-3 acid sphingomyelinase functions as a positive regulator of the DAF-2/AGE-1 signaling pathway and serves as a novel anti-aging target.

    Science.gov (United States)

    Kim, Yongsoon; Sun, Hong

    2012-01-01

    In C. elegans, the highly conserved DAF-2/insulin/insulin-like growth factor 1 receptor signaling (IIS) pathway regulates longevity, metabolism, reproduction and development. In mammals, acid sphingomyelinase (ASM) is an enzyme that hydrolyzes sphingomyelin to produce ceramide. ASM has been implicated in CD95 death receptor signaling under certain stress conditions. However, the involvement of ASM in growth factor receptor signaling under physiological conditions is not known. Here, we report that in vivo ASM functions as a positive regulator of the DAF-2/IIS pathway in C. elegans. We have shown that inactivation of asm-3 extends animal lifespan and promotes dauer arrest, an alternative developmental process. A significant cooperative effect on lifespan is observed between asm-3 deficiency and loss-of-function alleles of the age-1/PI 3-kinase, with the asm-3; age-1 double mutant animals having a mean lifespan 259% greater than that of the wild-type animals. The lifespan extension phenotypes caused by the loss of asm-3 are dependent on the functions of daf-16/FOXO and daf-18/PTEN. We have demonstrated that inactivation of asm-3 causes nuclear translocation of DAF-16::GFP protein, up-regulates endogenous DAF-16 protein levels and activates the downstream targeting genes of DAF-16. Together, our findings reveal a novel role of asm-3 in regulation of lifespan and diapause by modulating IIS pathway. Importantly, we have found that two drugs known to inhibit mammalian ASM activities, desipramine and clomipramine, markedly extend the lifespan of wild-type animals, in a manner similar to that achieved by genetic inactivation of the asm genes. Our studies illustrate a novel strategy of anti-aging by targeting ASM, which may potentially be extended to mammals.

  19. Economics of "essential use exemptions" for metered-dose inhalers under the Montreal Protocol.

    Science.gov (United States)

    DeCanio, Stephen J; Norman, Catherine S

    2007-10-01

    The Montreal Protocol on Substances that Deplete the Ozone Layer has led to rapid reductions in the use of ozone-depleting substances worldwide. However, the Protocol provides for "essential use exemptions" (EUEs) if there are no "technically and economically feasible" alternatives. An application that might qualify as an "essential use" is CFC-powered medical metered-dose inhalers (MDIs) for the treatment of asthma and chronic obstructive pulmonary disease (COPD), and the US and other nations have applied for exemptions in this case. One concern is that exemptions are necessary to ensure access to medications for low-income uninsureds. We examine the consequences of granting or withholding such exemptions, and conclude that government policies and private-sector programs are available that make it economically feasible to phase out chlorofluorocarbons (CFCs) in this application, thereby furthering the global public health objectives of the Montreal Protocol without compromising the treatment of patients who currently receive medication by means of MDIs.

  20. Chapter 1: Direct Normal Radiation

    Energy Technology Data Exchange (ETDEWEB)

    Myer, Daryl R.

    2016-04-15

    This chapter addresses the quantitative and qualitative aspects of the solar resource, the direct solar radiation. It discusses the total or integrated broadband direct beam extraterrestrial radiation (ETR). This total integrated irradiance is comprised of photons of electromagnetic radiation. The chapter also discusses the impact of the atmosphere and its effect upon the direct normal irradiance (DNI) beam radiation. The gases and particulates present in the atmosphere traversed by the direct beam reflect, absorb, and scatter differing spectral regions and proportions of the direct beam, and act as a variable filter. Knowledge of the available broadband DNI beam radiation resource data is essential in designing a concentrating photovoltaic (CPV) system. Spectral variations in the DNI beam radiation affect the performance of a CPV system depending on the solar cell technology used. The chapter describes propagation and scattering processes of circumsolar radiation (CSR), which includes the Mie scattering from large particles.

  1. Facilitators & barriers to organic waste and phosphorus re-use in Montreal

    Directory of Open Access Journals (Sweden)

    Geneviève S. Metson

    2015-10-01

    Full Text Available Abstract Cities have the capacity to play a key role in resource and pollution management through their decisions about organic waste. Often overlooked, but nevertheless essential, is the role that cities can play in increasing phosphorus (P recycling because cities are consumers of large amounts of P-dense food and producers of vast amounts of P-rich waste. Most cities do not take advantage of this potential, seeing P as simply another part of organic waste to be disposed of elsewhere. For example, in Montreal, Canada, only 6% of P in waste is currently recycled. We used semi-structured interviews with key stakeholders (19, participant observation (over 1.5 years, and document review to identify key barriers and facilitators for Montreal to achieve a high level of organic waste recycling through composting. We found that a provincial law mandating 100% recycling of organic matter has great potential to facilitate increased P recycling. However, lack of a shared vision about the role of government, private sector, and citizens in producing high quality compost from waste products is a barrier that inhibits this potential. Cultural inertia, lack of knowledge, and lack of infrastructure also act as barriers to increasing composting in Montreal. Urban agriculture could be a means to overcome some of these barriers as it currently benefits from strong citizen support and is both a consumer and producer of compost. However limited access to potential garden space and training and diversity in desired fertilizer qualities among gardeners somewhat limit this potential. Investing in increasing social capital, and specifically in connecting urban agriculture to waste management objectives, and in linking key stakeholders to co-create shared visions about how to produce high quality compost may act as a stepping stone towards increasing Montreal citizens’ knowledge about, and support for, increasing organic waste and thus P recycling.

  2. A post-Kyoto partner: Considering the Montreal Protocol as a tool to manage nitrous oxide

    Science.gov (United States)

    Mauzerall, D. L.; Kanter, D.; Ravishankara, A. R.; Daniel, J. S.; Portmann, R. W.; Grabiel, P.; Moomaw, W.; Galloway, J. N.

    2012-12-01

    While nitrous oxide (N2O) was recently identified as the largest remaining anthropogenic threat to the stratospheric ozone layer, it is currently regulated under the 1997 Kyoto Protocol due to its simultaneous ability to warm the climate. The threat N2O poses to the stratospheric ozone layer, coupled with the uncertain future of the international climate regime, motivates our exploration of issues that could be relevant to the Parties to the 1987 Montreal Protocol if they decide to take measures to manage N2O in the future. There are clear legal avenues for the Montreal Protocol and its parent treaty, the 1985 Vienna Convention, to regulate N2O, as well as several ways to share authority with the existing and future international climate treaties. N2O mitigation strategies exist to address its most significant anthropogenic sources, including agriculture, where behavioral practices and new technologies could contribute significantly to mitigation efforts. Existing policies managing N2O and other forms of reactive nitrogen could be harnessed and built upon by the Montreal Protocol's existing bodies to implement N2O controls. Given the tight coupling of the nitrogen cycle, such controls would likely simultaneously reduce emissions of reactive nitrogen and hence have co-benefits for ecosystems and public health. Nevertheless, there are at least three major regulatory challenges that are unique and central to N2O control: food security, equity, and the nitrogen cascade. The possible inclusion of N2O in the Montreal Protocol need not be viewed as a sign of the Kyoto Protocol's failure to adequately deal with climate change, given the complexity of the issue. Rather, it could represent an additional tool in the field of sustainable development diplomacy.lt;img border=0 src="images/B43K-06_B.jpg">

  3. Air Carrier's Liability for Damages According to the New Montreal Convention

    Directory of Open Access Journals (Sweden)

    Slobodan Kaštela

    2012-10-01

    Full Text Available The liability of air carriers in international air traffic is stillregulated by the Warsaw Convention from 1929and its amendments.In 1999the Montreal Convention was accepted, whichcompletely substitutes the rules contained in the Warsaw Conventionincluding all its later amendments, and the most importantmodifications have been made regarding the air can·iers'liabilities in case of passenger injury or death on intemationaI flights.

  4. Estimating the health benefits of planned public transit investments in Montreal.

    Science.gov (United States)

    Tétreault, Louis-François; Eluru, Naveen; Hatzopoulou, Marianne; Morency, Patrick; Plante, Celine; Morency, Catherine; Reynaud, Frederic; Shekarrizfard, Maryam; Shamsunnahar, Yasmin; Faghih Imani, Ahmadreza; Drouin, Louis; Pelletier, Anne; Goudreau, Sophie; Tessier, Francois; Gauvin, Lise; Smargiassi, Audrey

    2018-01-01

    Since public transit infrastructure affects road traffic volumes and influences transportation mode choice, which in turn impacts health, it is important to estimate the alteration of the health burden linked with transit policies. We quantified the variation in health benefits and burden between a business as usual (BAU) and a public transit (PT) scenarios in 2031 (with 8 and 19 new subway and train stations) for the greater Montreal region. Using mode choice and traffic assignment models, we predicted the transportation mode choice and traffic assignment on the road network. Subsequently, we estimated the distance travelled in each municipality by mode, the minutes spent in active transportation, as well as traffic emissions. Thereafter we estimated the health burden attributed to air pollution and road traumas and the gains associated with active transportation for both the BAU and PT scenarios. We predicted a slight decrease of overall trips and kilometers travelled by car as well as an increase of active transportation for the PT in 2031 vs the BAU. Our analysis shows that new infrastructure will reduce the overall burden of transportation by 2.5 DALYs per 100,000 persons. This decrease is caused by the reduction of road traumas occurring in the inner suburbs and central Montreal region as well as gains in active transportation in the inner suburbs. Based on the results of our study, transportation planned public transit projects for Montreal are unlikely to reduce drastically the burden of disease attributable to road vehicles and infrastructures in the Montreal region. The impact of the planned transportation infrastructures seems to be very low and localized mainly in the areas where new public transit stations are planned. Copyright © 2017 Elsevier Inc. All rights reserved.

  5. Network collaboration of organizations for homeless individuals in the Montreal region

    Directory of Open Access Journals (Sweden)

    Marie-Josée Fleury

    2014-02-01

    Full Text Available Introduction: We know little about the intensity and determinants of interorganisational collaboration within the homeless network. This study describes the characteristics and relationships (along with the variables predicting their degree of interorganisational collaboration of 68 organisations of such a network in Montreal (Quebec, Canada. Theory and methods: Data were collected primarily through a self-administered questionnaire. Descriptive analyses were conducted followed by social network and multivariate analyses. Results: The Montreal homeless network has a high density (50.5% and a decentralised structure and maintains a mostly informal collaboration with the public and cross-sectorial sectors. The network density showed more frequent contacts among four types of organisations which could point to the existence of cliques. Four variables predicted interorganisational collaboration: organisation type, number of services offered, volume of referrals and satisfaction with the relationships with public organisations. Conclusions and discussion: The Montreal homeless network seems adequate to address non-complex homelessness problems. Considering, however, that most homeless individuals present chronic and complex profiles, it appears necessary to have a more formal and better integrated network of homeless organisations, particularly in the health and social service sectors, in order to improve services.

  6. Socioeconomic geographical links to human immunodeficiency virus seroprevalence among childbearing women in Montreal, 1989-1993.

    Science.gov (United States)

    Hankins, C; Tran, T; Hum, L; Laberge, C; Lapointe, N; Lepine, D; Montpetit, M; O'Shaughnessy, M V

    1998-08-01

    To describe the socioeconomic profiles of geographical areas on Montreal Island in which human immunodeficiency virus (HIV) seropositive women delivering live births between 1989 and 1993 reside. Leftover dried blood spot filter paper specimens collected from newborns were irretrievably unlinked from identifying information prior to testing. Seroprevalence estimates were calculated based on Western blot confirmed positive samples. Using data from the Canadian census, Revenue Canada, and provincial birth records, the socioeconomic characteristics of postal zones in which seropositive mothers reside were described. Montreal Island had an overall 5-year HIV seroprevalence rate estimate of 16.6 (95% CI: 14.1-19.3) per 10000 childbearing women. Areas in which at least one seropositive woman gave birth had lower mean infant birthweights and higher percentages of single mothers and single-parent families. The HIV-positive neonatal blood specimens were more likely to originate from areas where a higher proportion of residents reported less education, greater unemployment, and lower income. Higher HIV infection rates were found among childbearing women from lower socioeconomic areas of Montreal. Increased understanding of the relationship between socioeconomic status and HIV acquisition and transmission is required to inform the development of targeted HIV prevention programmes.

  7. Bronchodilatory and anti-inflammatory effects of ASM-024, a nicotinic receptor ligand, developed for the treatment of asthma.

    Directory of Open Access Journals (Sweden)

    Evelyne Israël Assayag

    Full Text Available Conventional asthma and COPD treatments include the use of bronchodilators, mainly β2-adrenergic agonists, muscarinic receptor antagonists and corticosteroids or leukotriene antagonists as anti-inflammatory agents. These active drugs are administered either separately or given as a fixed-dose combination medication into a single inhaler. ASM-024, a homopiperazinium compound, derived from the structural modification of diphenylmethylpiperazinium (DMPP, has been developed to offer an alternative mechanism of action that could provide symptomatic control through combined anti-inflammatory and bronchodilator properties in a single entity. A dose-dependent inhibition of cellular inflammation in bronchoalveolar lavage fluid was observed in ovalbumin-sensitized mice, subsequently treated for 3 days by nose-only exposure with aerosolized ASM-024 at doses up to 3.8 mg/kg (ED50 = 0.03 mg/kg. The methacholine ED250 values indicated that airway hyperresponsivenness (AHR to methacholine decreased following ASM-024 administration by inhalation at a dose of 1.5 mg/kg, with a value of 0.145 ± 0.032 mg/kg for ASM 024-treated group as compared to 0.088 ± 0.023 mg/kg for untreated mice. In in vitro isometric studies, ASM-024 elicited dose-dependent relaxation of isolated mouse tracheal, human, and dog bronchial preparations contracted with methacholine and guinea pig tracheas contracted with histamine. ASM-024 showed also a dose and time dependant protective effect on methacholine-induced contraction. Overall, with its combined anti-inflammatory, bronchodilating and bronchoprotective properties, ASM-024 may represent a new class of drugs with a novel pharmacological approach that could prove useful for the chronic maintenance treatment of asthma and, possibly, COPD.

  8. Neurospora crassa ASM-1 complements the conidiation defect in a stuA mutant of Aspergillus nidulans.

    Science.gov (United States)

    Chung, Dawoon; Upadhyay, Srijana; Bomer, Brigitte; Wilkinson, Heather H; Ebbole, Daniel J; Shaw, Brian D

    2015-01-01

    Aspergillus nidulans StuA and Neurospora crassa ASM-1 are orthologous APSES (ASM-1, PHD1, SOK2, Efg1, StuA) transcription factors conserved across a diverse group of fungi. StuA and ASM-1 have roles in asexual (conidiation) and sexual (ascospore formation) development in both organisms. To address the hypothesis that the last common ancestor of these diverse fungi regulated conidiation with similar genes, asm-1 was introduced into the stuA1 mutant of A. nidulans. Expression of asm-1 complemented defective conidiophore morphology and restored conidia production to wild type levels in stuA1. Expression of asm-1 in the stuA1 strain did not rescue the defect in sexual development. When the conidiation regulator AbaA was tagged at its C-terminus with GFP in A. nidulans, it localized to nuclei in phialides. When expressed in the stuA1 mutant, AbaA::GFP localized to nuclei in conidiophores but no longer was confined to phialides, suggesting that expression of AbaA in specific cell types of the conidiophore was conditioned by StuA. Our data suggest that the function in conidiation of StuA and ASM-1 is conserved and support the view that, despite the great morphological and ontogenic diversity of their condiphores, the last common ancestor of A. nidulans and N. crassa produced an ortholog of StuA that was involved in conidiophore development. © 2015 by The Mycological Society of America.

  9. Bronchodilatory and anti-inflammatory effects of ASM-024, a nicotinic receptor ligand, developed for the treatment of asthma.

    Science.gov (United States)

    Assayag, Evelyne Israël; Beaulieu, Marie-Josée; Cormier, Yvon

    2014-01-01

    Conventional asthma and COPD treatments include the use of bronchodilators, mainly β2-adrenergic agonists, muscarinic receptor antagonists and corticosteroids or leukotriene antagonists as anti-inflammatory agents. These active drugs are administered either separately or given as a fixed-dose combination medication into a single inhaler. ASM-024, a homopiperazinium compound, derived from the structural modification of diphenylmethylpiperazinium (DMPP), has been developed to offer an alternative mechanism of action that could provide symptomatic control through combined anti-inflammatory and bronchodilator properties in a single entity. A dose-dependent inhibition of cellular inflammation in bronchoalveolar lavage fluid was observed in ovalbumin-sensitized mice, subsequently treated for 3 days by nose-only exposure with aerosolized ASM-024 at doses up to 3.8 mg/kg (ED50 = 0.03 mg/kg). The methacholine ED250 values indicated that airway hyperresponsivenness (AHR) to methacholine decreased following ASM-024 administration by inhalation at a dose of 1.5 mg/kg, with a value of 0.145 ± 0.032 mg/kg for ASM 024-treated group as compared to 0.088 ± 0.023 mg/kg for untreated mice. In in vitro isometric studies, ASM-024 elicited dose-dependent relaxation of isolated mouse tracheal, human, and dog bronchial preparations contracted with methacholine and guinea pig tracheas contracted with histamine. ASM-024 showed also a dose and time dependant protective effect on methacholine-induced contraction. Overall, with its combined anti-inflammatory, bronchodilating and bronchoprotective properties, ASM-024 may represent a new class of drugs with a novel pharmacological approach that could prove useful for the chronic maintenance treatment of asthma and, possibly, COPD.

  10. Chapter 1: Standard Model processes

    OpenAIRE

    Becher, Thomas

    2017-01-01

    This chapter documents the production rates and typical distributions for a number of benchmark Standard Model processes, and discusses new dynamical phenomena arising at the highest energies available at this collider. We discuss the intrinsic physics interest in the measurement of these Standard Model processes, as well as their role as backgrounds for New Physics searches.

  11. Energy and wastes. Chapter 1

    International Nuclear Information System (INIS)

    2002-01-01

    In the Chapter 1 'Energy and wastes' it is shown the wastes generation inevitability at power production, because there are no absolutely wasteless technologies. After energy production technologies analysis the data that nuclear energy is most ecologically acceptable at maintenance related radiation safety measures

  12. The ASM-NSF Biology Scholars Program: An Evidence-Based Model for Faculty Development

    Directory of Open Access Journals (Sweden)

    Amy L. Chang

    2016-05-01

    Full Text Available The American Society for Microbiology (ASM established its ASM-NSF (National Science Foundation Biology Scholars Program (BSP to promote undergraduate education reform by 1 supporting biologists to implement evidence-based teaching practices, 2 engaging life science professional societies to facilitate biologists’ leadership in scholarly teaching within the discipline, and 3 participating in a teaching community that fosters disciplinary-level science, technology, engineering, and mathematics (STEM reform. Since 2005, the program has utilized year-long residency training to provide a continuum of learning and practice centered on principles from the scholarship of teaching and learning (SoTL to more than 270 participants (“scholars” from biology and multiple other disciplines. Additionally, the program has recruited 11 life science professional societies to support faculty development in SoTL and discipline-based education research (DBER. To identify the BSP’s long-term outcomes and impacts, ASM engaged an external evaluator to conduct a study of the program’s 2010­–2014 scholars (n = 127 and society partners. The study methods included online surveys, focus groups, participant observation, and analysis of various documents. Study participants indicate that the program achieved its proposed goals relative to scholarship, professional society impact, leadership, community, and faculty professional development. Although participants also identified barriers that hindered elements of their BSP participation, findings suggest that the program was essential to their development as faculty and provides evidence of the BSP as a model for other societies seeking to advance undergraduate science education reform. The BSP is the longest-standing faculty development program sponsored by a collective group of life science societies. This collaboration promotes success across a fragmented system of more than 80 societies representing the life

  13. The ASM-NSF Biology Scholars Program: An Evidence-Based Model for Faculty Development.

    Science.gov (United States)

    Chang, Amy L; Pribbenow, Christine M

    2016-05-01

    The American Society for Microbiology (ASM) established its ASM-NSF (National Science Foundation) Biology Scholars Program (BSP) to promote undergraduate education reform by 1) supporting biologists to implement evidence-based teaching practices, 2) engaging life science professional societies to facilitate biologists' leadership in scholarly teaching within the discipline, and 3) participating in a teaching community that fosters disciplinary-level science, technology, engineering, and mathematics (STEM) reform. Since 2005, the program has utilized year-long residency training to provide a continuum of learning and practice centered on principles from the scholarship of teaching and learning (SoTL) to more than 270 participants ("scholars") from biology and multiple other disciplines. Additionally, the program has recruited 11 life science professional societies to support faculty development in SoTL and discipline-based education research (DBER). To identify the BSP's long-term outcomes and impacts, ASM engaged an external evaluator to conduct a study of the program's 2010-2014 scholars (n = 127) and society partners. The study methods included online surveys, focus groups, participant observation, and analysis of various documents. Study participants indicate that the program achieved its proposed goals relative to scholarship, professional society impact, leadership, community, and faculty professional development. Although participants also identified barriers that hindered elements of their BSP participation, findings suggest that the program was essential to their development as faculty and provides evidence of the BSP as a model for other societies seeking to advance undergraduate science education reform. The BSP is the longest-standing faculty development program sponsored by a collective group of life science societies. This collaboration promotes success across a fragmented system of more than 80 societies representing the life sciences and helps

  14. ASME N510 test results for Savannah River Site AACS filter compartments

    Energy Technology Data Exchange (ETDEWEB)

    Paul, J.D.; Punch, T.M. [Westinghouse Savannah River Company, Aiken, SC (United States)

    1995-02-01

    The K-Reactor at the Savannah River Site recently implemented design improvements for the Airborne Activity Confinement System (AACS) by procuring, installing, and testing new Air Cleaning Units, or filter compartments, to ASME AG-11, N509, and N510 requirements. Specifically, these new units provide documentable seismic resistance to a Design Basis Accident earthquake, provide 2 inch adsorber beds with 0.25 second residence time, and meet all AG-1, N509, and N510 requirements for testability and maintainability. This paper presents the results of the Site acceptance testing and discusses an issue associated with sample manifold qualification testing.

  15. ASTM and ASME-BPE Standards--Complying with the Needs of the Pharmaceutical Industry.

    Science.gov (United States)

    Huitt, William M

    2011-01-01

    Designing and building a pharmaceutical facility requires the owner, engineer of record, and constructor to be knowledgeable with regard to the industry codes and standards that apply to this effort. Up until 1997 there were no industry standards directed at the needs and requirements of the pharmaceutical industry. Prior to that time it was a patchwork effort at resourcing and adopting nonpharmaceutical-related codes and standards and then modifying them in order to meet the more stringent requirements of the Food and Drug Administration (FDA). In 1997 the American Society of Mechanical Engineers (ASME) published the first Bioprocessing Equipment (BPE) Standard. Through harmonization efforts this relatively new standard has brought together, scrutinized, and refined industry accepted methodologies together with FDA compliance requirements, and has established an American National Standard that provides a comprehensive set of standards that are integral to the pharmaceutical industry. This article describes various American National Standards, including those developed and published by the American Society for Testing and Materials (ASTM), and how they apply to the pharmaceutical industry. It goes on to discuss the harmonization effort that takes place between the various standards developers in an attempt to prevent conflicts and omissions between the many standards. Also included are examples of tables and figures taken from the ASME-BPE Standard. These examples provide the reader with insight to the relevant content of the ASME-BPE Standard. Designing and building a pharmaceutical facility requires the owner, engineer of record, and constructor to be knowledgeable with regard to the industry codes and standards that apply to this effort. Up until 1997 there were no industry standards directed at the needs and requirements of the pharmaceutical industry. Prior to that time it was a patchwork effort at resourcing and adopting nonpharmaceutical-related codes and

  16. Radiografia Torácica em Crise Asmática

    OpenAIRE

    Sanches, Marcos; Marques, Patricia; Oliveira, Elisabete; Lopes, Aldina Canteiro

    2013-01-01

    Criança de oito anos, asmática que iniciou de forma súbita opressão torácica, disfagia e cansaço, motivo pelo qual recorreu ao serviço de urgência. Ao exame físico apresentava tiragem intercostal, polipneia e edema supraclavicular à direita crepitante. A auscultação pulmonar revelava murmúrio vesicular diminuído bilateralmente, aumento do tempo expiratório com sibilos dispersos. A radiografia (Rx) de tórax demonstrou sinais de pneumomediastino (figura 1), pelo que iniciou repouso e tratamento...

  17. Materials and design bases issues in ASME Code Case N-47

    International Nuclear Information System (INIS)

    Huddleston, R.L.; Swindeman, R.W.

    1993-04-01

    A preliminary evaluation of the design bases (principally ASME Code Case N-47) was conducted for design and operation of reactors at elevated temperatures where the time-dependent effects of creep, creep-fatigue, and creep ratcheting are significant. Areas where Code rules or regulatory guides may be lacking or inadequate to ensure the operation over the expected life cycles for the next-generation advanced high-temperature reactor systems, with designs to be certified by the US Nuclear Regulatory Commission, have been identified as unresolved issues. Twenty-two unresolved issues were identified and brief scoping plans developed for resolving these issues

  18. Application of the ASME code in designing containment vessels for packages used to transport radioactive materials

    International Nuclear Information System (INIS)

    Raske, D.T.; Wang, Z.

    1992-01-01

    The primary concern governing the design of shipping packages containing radioactive materials is public safety during transport. When these shipments are within the regulatory jurisdiction of the US Department of Energy, the recommended design criterion for the primary containment vessel is either Section III or Section VIII, Division 1, of the ASME Boiler and Pressure Vessel Code, depending on the activity of the contents. The objective of this paper is to discuss the design of a prototypic containment vessel representative of a packaging for the transport of high-level radioactive material

  19. Nupack, the new ASME code for radioactive material transportation packaging containments

    International Nuclear Information System (INIS)

    Turula, P.

    1998-01-01

    The American Society of Mechanical Engineers (ASME) has added a new division to the nuclear construction section of its Boiler and Pressure Vessel Code (B and PVC). This Division, commonly referred to as Nupack, has been written to provide a consistent set of technical requirements for containment vessels of transportation packagings for high-level radioactive materials. This paper provides an introduction to Nupack, discusses some of its technical provisions, and describes how it can be used for the design and construction of packaging components. Nupack's general provisions and design requirements are emphasized, while treatment of materials, fabrication and inspection is left for another paper

  20. Batse/Sax and Batse/RXTE-ASM Joint Spectral Studies of GRBs

    Science.gov (United States)

    Paciesas, William S.

    2002-01-01

    We proposed to make joint spectral analysis of gamma-ray bursts (GRBs) in the BATSE data base that are located within the fields of view of either the BeppoSAX wide field cameras (WFCs) or the RXTE all-sky monitor (ASM). The very broad-band coverage obtained in this way would facilitate various studies of GRB spectra that are difficult to perform with BATSE data alone. Unfortunately, the termination of the CGRO mission in June 2000 was not anticipated at the time of the proposal, and the sample of common events turned out to be smaller than we would have liked.

  1. Robust boundary detection of left ventricles on ultrasound images using ASM-level set method.

    Science.gov (United States)

    Zhang, Yaonan; Gao, Yuan; Li, Hong; Teng, Yueyang; Kang, Yan

    2015-01-01

    Level set method has been widely used in medical image analysis, but it has difficulties when being used in the segmentation of left ventricular (LV) boundaries on echocardiography images because the boundaries are not very distinguish, and the signal-to-noise ratio of echocardiography images is not very high. In this paper, we introduce the Active Shape Model (ASM) into the traditional level set method to enforce shape constraints. It improves the accuracy of boundary detection and makes the evolution more efficient. The experiments conducted on the real cardiac ultrasound image sequences show a positive and promising result.

  2. Draft ASME code case on ductile cast iron for transport packaging

    Energy Technology Data Exchange (ETDEWEB)

    Saegusa, T. [Central Research Inst. of Electric Power Industry, Abiko (Japan); Arai, T. [Central Research Inst. of Electric Power Industry, Yokosuka (Japan); Hirose, M. [Nuclear Fuel Transport Co., Ltd., Tokyo (Japan); Kobayashi, T. [Nippon Chuzo, Kawasaki (Japan); Tezuka, Y. [Mitsubishi Materials Co., Tokyo (Japan); Urabe, N. [Kokan Keisoku K. K., Kawasaki (Japan); Hueggenberg, R. [GNB, Essen (Germany)

    2004-07-01

    The current Rules for Construction of ''Containment Systems for Storage and Transport Packagings of Spent Nuclear Fuel and High Level Radioactive Material and Waste'' of Division 3 in Section III of ASME Code (2001 Edition) does not include ductile cast iron in its list of materials permitted for use. The Rules specify required fracture toughness values of ferritic steel material for nominal wall thickness 5/8 to 12 inches (16 to 305 mm). New rule for ductile cast iron for transport packaging of which wall thickness is greater than 12 inches (305mm) is required.

  3. Summary of design of nuclear vessels and piping to ASME III (NB, NC, ND) and vessels to BS 5500

    International Nuclear Information System (INIS)

    Harrop, L.P.

    1992-01-01

    There is a hierarchy of design code requirements for pressurised components, starting with non-nuclear codes as the minimum and progressing through the ASME III nuclear Classes 3, 2, 1. In establishing and assessing the safety justifications of nuclear plants it is important to have an appreciation of the gradation of requirements in the ASME III design rules and how these go beyond non-nuclear component design rules. There are two broad aspects to the structural integrity of pressurised components, namely the achievement of integrity and the demonstration of integrity. The technical requirements of design codes are associated with achieving integrity while the documentary aspects are usually associated with demonstrating integrity. In practice documents also have a part in achieving integrity in the communication of information between different organisations and personnel involved in the design process. It is not possible to assign simple numerical measures to the relative integrity afforded by non-nuclear codes and the three Classes of ASME III. Instead it is necessary to compare the different requirements of the rules for the various technical and documentary aspects. This paper summarises the most important technical and documentary aspects of the three Classes of the ASME III Code for vessels and the non-nuclear code BS 5500. A similar summary is also provided for the three Classes of ASME III rules for piping. The intention is that the paper provides a basis for appreciating the relative integrity afforded by these various rules. (author)

  4. Argel, Buenos Aires, Montreal: el Comité de Cine del Tercer Mundo (1973 / 1974 / Algiers, Buenos Aires, Montreal: the Third World Cinema Committee (1973 / 1974

    Directory of Open Access Journals (Sweden)

    Mariano Mestman

    2017-02-01

    Full Text Available El encuentro de cineastas de Argel (Argelia en diciembre de 1973 es bien conocido en los estudios sobre el cine del Tercer Mundo. En cuanto oportunidad de intercambio y discusión, este encuentro permitió la organización del trabajo de los cineastas y focalizó el debate en tres ejes principales: la contribución del cine a los procesos de liberación nacional, la descolonización de las pantallas del Tercer Mundo y la lucha contra la «alienación cultural». El resultado más importante fue la creación del Comité de Cine del Tercer Mundo. Solo seis meses más tarde, un nuevo encuentro tuvo lugar en Buenos Aires (Argentina. Por un lado, el presente ensayo muestra cómo un proyecto político-cinematográfico (el «tercermundismo» fue tomando forma gradualmente durante esos años y destaca el rol de ambas reuniones en la promoción de esta nueva identidad político-cultural. Por otro, este trabajo también propone la necesidad de incorporar a esta historia otro evento decisivo: los Rencontres Internationales pour un Nouveau Cinema, realizados en Montreal en 1974. Poco considerado incluso por la bibliografía especializada, este encuentro puede considerarse el más importante del cine polí- tico mundial de los años sesenta y setenta. Dada la cantidad y diversidad de los participantes de Europa, Estados Unidos, África y América Latina, la conferencia de Montreal fue crucial en la constitución del diálogo entre los cineastas políticos del Primer Mundo y la tendencia tercermundista construida entre Argel y Buenos Aires.Palabras clave: Tercer Mundo, tercermundismo, Tercer Cine, Nuevo Cine Latinoamericano, Federación Panafricana de CineastasAbstract:The filmmakers meeting held in Algiers (Algeria in December 1973 is a wellknown event among Third World Cinema´s studies. As an opportunity to exchange and discussion, this gathering organised the work of Third World filmmakers and focused the debate on three main issues: the contribution of

  5. Chapter 07: Species description pages

    Science.gov (United States)

    Alex C. Wiedenhoeft

    2011-01-01

    These pages are written to be the final step in the identification process; you will be directed to them by the key in Chapter 6. Each species or group of similar species in the same genus has its own set of pages. The information in the first page describes the characteristics of the wood covered in the manual. The page shows images of similar or confusable woods,...

  6. Vegetation and acidification, Chapter 5

    Science.gov (United States)

    David R. DeWalle; James N. Kochenderfer; Mary Beth Adams; Gary W. Miller

    2006-01-01

    In this chapter, the impact of watershed acidification treatments on WS3 at the Fernow Experimental Forest (FEF) and at WS9 on vegetation is presented and summarized in a comprehensive way for the first time. WS7 is used as a vegetative reference basin for WS3, while untreated plots within WS9 are used as a vegetative reference for WS9. Bioindicators of acidification...

  7. Broncoespasmo induzido pelo exercício em adolescentes asmáticos obesos e não-obesos

    OpenAIRE

    Lopes,Wendell Arthur; Rosário,Nelson; Leite,Neiva

    2010-01-01

    OBJETIVO: Avaliar e comparar a frequência e intensidade do broncoespasmo induzido pelo exercício (BIE) em adolescentes asmáticos obesos e não-obesos. MÉTODOS: Estudo transversal e descritivo realizado com 39 adolescentes de ambos os sexos, com idade entre dez e 16 anos, divididos em dois grupos conforme o histórico clínico de asma e/ou rinite alérgica e o índice de massa corporal: asmáticos obesos (n=18); asmáticos não-obesos (n=21). Utilizou-se o teste de broncoprovocação com exercício para ...

  8. Comparison of ASME Code NB-3200 and NB-3600 results for fatigue analysis of B31.1 branch nozzles

    International Nuclear Information System (INIS)

    Nitzel, M.E.; Ware, A.G.; Morton, D.K.

    1996-01-01

    Fatigue analyses wre conducted on two reactor coolant system branch nozzles in an operating PWR designed to the B31.1 Code, for which no explicit fatigue analysis was required by the licensing basis. These analyses were performed as part of resolving issues connected with NRC's Fatigue Action Plan to determine if the cumulative usage factor (CUF) for these nozzles, using the 1992 ASME Code and representative PWR transients, were comparable to nozzles designed and analyzed to the ASME Code. Both NB-3200 and NB-3600 ASME Code methods were used. NB-3200 analyses included the development of finite element models for each nozzle. Although detailed thermal transients were not available for the plant analyzed, representative transients from similar PWRs were applied in each method. CUFs calculated using NB-3200 methods were significantly less than using NB-3600. The paper points out differences in analysis methods and highlights difficulties and unknowns in performing more detailed analyses to reduce conservative assumptions

  9. When a Plant Resistance Inducer Leaves the Lab for the Field: Integrating ASM into Routine Apple Protection Practices.

    Science.gov (United States)

    Marolleau, Brice; Gaucher, Matthieu; Heintz, Christelle; Degrave, Alexandre; Warneys, Romain; Orain, Gilles; Lemarquand, Arnaud; Brisset, Marie-Noëlle

    2017-01-01

    Plant resistance inducers, also called elicitors, could be useful to reduce the use of pesticides. However, their performance in controlling diseases in the field remains unsatisfactory due to lack of specific knowledge of how they can integrate crop protection practices. In this work, we focused on apple crop and acibenzolar- S -methyl (ASM), a well-known SAR (systemic acquired resistance) inducer of numerous plant species. We provide a protocol for orchard-effective control of apple scab due to the ascomycete fungus Venturia inaequalis , by applying ASM in combination with a light integrated pest management program. Besides we pave the way for future optimization levers by demonstrating in controlled conditions (i) the high influence of apple genotypes, (ii) the ability of ASM to prime defenses in newly formed leaves, (iii) the positive effect of repeated elicitor applications, (iv) the additive effect of a thinning fruit agent.

  10. Evaluation of conservatisms and environmental effects in ASME Code, Section III, Class 1 fatigue analysis

    International Nuclear Information System (INIS)

    Deardorff, A.F.; Smith, J.K.

    1994-08-01

    This report documents the results of a study regarding the conservatisms in ASME Code Section 3, Class 1 component fatigue evaluations and the effects of Light Water Reactor (LWR) water environments on fatigue margins. After review of numerous Class 1 stress reports, it is apparent that there is a substantial amount of conservatism present in many existing component fatigue evaluations. With little effort, existing evaluations could be modified to reduce the overall predicted fatigue usage. Areas of conservatism include design transients considerably more severe than those experienced during service, conservative grouping of transients, conservatisms that have been removed in later editions of Section 3, bounding heat transfer and stress analysis, and use of the ''elastic-plastic penalty factor'' (K 3 ). Environmental effects were evaluated for two typical components that experience severe transient thermal cycling during service, based on both design transients and actual plant data. For all reasonable values of actual operating parameters, environmental effects reduced predicted margins, but fatigue usage was still bounded by the ASME Section 3 fatigue design curves. It was concluded that the potential increase in predicted fatigue usage due to environmental effects should be more than offset by decreases in predicted fatigue usage if re-analysis were conducted to reduce the conservatisms that are present in existing component fatigue evaluations

  11. Code cases for implementing risk-based inservice testing in the ASME OM code

    Energy Technology Data Exchange (ETDEWEB)

    Rowley, C.W.

    1996-12-01

    Historically inservice testing has been reasonably effective, but quite costly. Recent applications of plant PRAs to the scope of the IST program have demonstrated that of the 30 pumps and 500 valves in the typical plant IST program, less than half of the pumps and ten percent of the valves are risk significant. The way the ASME plans to tackle this overly-conservative scope for IST components is to use the PRA and plant expert panels to create a two tier IST component categorization scheme. The PRA provides the quantitative risk information and the plant expert panel blends the quantitative and deterministic information to place the IST component into one of two categories: More Safety Significant Component (MSSC) or Less Safety Significant Component (LSSC). With all the pumps and valves in the IST program placed in MSSC or LSSC categories, two different testing strategies will be applied. The testing strategies will be unique for the type of component, such as centrifugal pump, positive displacement pump, MOV, AOV, SOV, SRV, PORV, HOV, CV, and MV. A series of OM Code Cases are being developed to capture this process for a plant to use. One Code Case will be for Component Importance Ranking. The remaining Code Cases will develop the MSSC and LSSC testing strategy for type of component. These Code Cases are planned for publication in early 1997. Later, after some industry application of the Code Cases, the alternative Code Case requirements will gravitate to the ASME OM Code as appendices.

  12. Modelling the biological performance of a side-stream membrane bioreactor using ASM1.

    Science.gov (United States)

    Tian, Ke-Jun; Liu, Xin-Ai; Jiang, Tao; Kennedy, M D; Schippers, J C; Vanrolleghem, P A

    2004-01-01

    Membrane bioreactors (MBRs) are attracting global interest but the mathematical modeling of the biological performance of MBRs remains very limited. This study focuses on the modelling of a side-stream MBR system using Activated Sludge Model No. 1 (ASM1), and comparing the results with the modelling of traditional activated sludge processes. ASM1 parameters relevant for the long-term biological behaviour in MBR systems were calibrated (i.e. Y(H) = 0.72gCOD/gCOD, Y(A) = 0.25gCOD/gN, b(H) = 0.25 d(-1), b(A) = 0.080 d(-1) and f(P) = 0.06), and generally agreed with the parameters in traditional activated sludge processes, with the exception that a higher autotrophic biomass decay rate was observed in the MBR. A sensitivity analysis for steady state operation and DO dynamics suggested that the biological performance of the MBR system (the sludge concentration, effluent quality and the DO dynamics) are very sensitive to the parameters(i.e. Y(H), Y(A), b(H), b(A), micro(maxH) and micro(maxA)), and influent wastewater components(X(I), S(S), X(S), S(NH)).

  13. ASM1 dynamic calibration and long-term validation for an intermittently aerated WWTP.

    Science.gov (United States)

    Marquot, A; Stricker, A E; Racault, Y

    2006-01-01

    Activated sludge models, and ASM1 in particular, are well recognised and useful mathematical representations of the macroscopic processes involved in the biological degradation of the pollution carried by wastewater. Nevertheless, the use of these models through simulation software requires a careful methodology for their calibration (determination of the model parameters' values) and the validation step (verification with an independent data set). This paper presents the methodology and the results of dynamic calibration and validation tasks as a prior work to a modelling project for defining a reference guideline destined to French designers and operators. To reach these goals, a biological nutrient removal (BNR) wastewater treatment plant (WWTP) with intermittent aeration was selected and monitored for 2 years. Two sets of calibrated parameters are given and discussed. The results of the long-term validation task are presented through a 2-month simulation with lots of operation changes. Finally, it is concluded that, even if calibrating ASM1 with a high degree of confidence with a single set of parameters was not possible, the results of the calibration are sufficient to obtain satisfactory results over long-term dynamic simulation. However, simulating long periods reveals specific calibration issues such as the variation of the nitrification capacity due to external events.

  14. A strategy for implementation of experience based seismic equipment qualification in IEEE and ASME industry standards

    International Nuclear Information System (INIS)

    Adams, T.M.

    1996-01-01

    In the past 20 years, extensive data on the performance of mechanical and electric equipment during actual strong motion earthquakes and seismic qualification tests has been accumulated. Recognizing that an experience based approach provides a technically sound and cost effective method for the seismic qualification of some or certain equipment, the IEEE Nuclear Power Engineering Committee and the ASME Committee on Qualification of Mechanical Equipment established a Special Working Group to investigate the incorporation of experienced based methods into the industry consensus codes and standards currently used in the seismic qualification of Seismic Category Nuclear Power Plant equipment. This paper presents the strategy (course of action) which was developed by the Special Working Group for meeting this objective of incorporation of experience based seismic qualification standards used in the design and seismic qualification of seismic category nuclear power plant equipment. This strategy was recommended to both chartering organizations, the IEEE Nuclear Power Engineering Committee and the ASME Committee on Qualification of Mechanical Equipment for their consideration and implementation. The status of the review and implementation of the Special Working Group's recommended strategy by the sponsoring organization is also discussed

  15. Description of comprehensive pump test change to ASME OM code, subsection ISTB

    International Nuclear Information System (INIS)

    Hartley, R.S.

    1994-01-01

    The American Society of Mechanical Engineers (ASME) Operations and Maintenance (OM) Main Committee and Board on Nuclear Codes and Standards (BNCS) recently approved changes to ASME OM Code-1990, Subsection ISTB, Inservice Testing of Pumps in Light-Water Reactor Power Plants. The changes will be included in the 1994 addenda to ISTB. The changes, designated as the comprehensive pump test, incorporate a new, improved philosophy for testing safety-related pumps in nuclear power plants. An important philosophical difference between the open-quotes old codeclose quotes inservice testing (IST) requirements and these changes is that the changes concentrate on less frequent, more meaningful testing while minimizing damaging and uninformative low-flow testing. The comprehensive pump test change establishes a more involved biannual test for all pumps and significantly reduces the rigor of the quarterly test for standby pumps. The increased rigor and cost of the biannual comprehensive tests are offset by the reduced cost of testing and potential damage to the standby pumps, which comprise a large portion of the safety-related pumps at most plants. This paper provides background on the pump testing requirements, discusses potential industry benefits of the change, describes the development of the comprehensive pump test, and gives examples and reasons for many of the specific changes. This paper also describes additional changes to ISTB that will be included in the 1994 addenda that are associated with, but not part of, the comprehensive pump test

  16. Application of adjusted subpixel method (ASM) in HRCT measurements of the bronchi in bronchial asthma patients and healthy individuals.

    Science.gov (United States)

    Mincewicz, Grzegorz; Rumiński, Jacek; Krzykowski, Grzegorz

    2012-02-01

    Recently, we described a model system which included corrections of high-resolution computed tomography (HRCT) bronchial measurements based on the adjusted subpixel method (ASM). To verify the clinical application of ASM by comparing bronchial measurements obtained by means of the traditional eye-driven method, subpixel method alone and ASM in a group comprised of bronchial asthma patients and healthy individuals. The study included 30 bronchial asthma patients and the control group comprised of 20 volunteers with no symptoms of asthma. The lowest internal and external diameters of the bronchial cross-sections (ID and ED) and their derivative parameters were determined in HRCT scans using: (1) traditional eye-driven method, (2) subpixel technique, and (3) ASM. In the case of the eye-driven method, lower ID values along with lower bronchial lumen area and its percentage ratio to total bronchial area were basic parameters that differed between asthma patients and healthy controls. In the case of the subpixel method and ASM, both groups were not significantly different in terms of ID. Significant differences were observed in values of ED and total bronchial area with both parameters being significantly higher in asthma patients. Compared to ASM, the eye-driven method overstated the values of ID and ED by about 30% and 10% respectively, while understating bronchial wall thickness by about 18%. Results obtained in this study suggest that the traditional eye-driven method of HRCT-based measurement of bronchial tree components probably overstates the degree of bronchial patency in asthma patients. Copyright © 2011 Elsevier Ireland Ltd. All rights reserved.

  17. Low appendicular skeletal muscle mass (ASM) with limited mobility and poor health outcomes in middle-aged African Americans.

    Science.gov (United States)

    Malmstrom, Theodore K; Miller, Douglas K; Herning, Margaret M; Morley, John E

    2013-09-01

    Recent efforts to provide a consensus definition propose that sarcopenia be considered a clinical syndrome associated with the loss of both skeletal muscle mass and muscle function that occurs with aging. Validation of sarcopenia definitions that include both low muscle mass and poor muscle function is needed. In the population-based African American Health (AAH) study (N = 998 at baseline/wave 1), muscle mass and mobility were evaluated in a clinical testing center in a subsample of N = 319 persons (ages 52-68) at wave 4 (2004). Muscle mass was measured using dual energy x-ray absorptiometry and mobility by a 6-min walk test and 4-m gait walk test. Height corrected appendicular skeletal mass (ASM; 9.0 ± 1.5 in n = 124 males, 8.3 ± 2.2 in n = 195 females) was computed as total lean muscle mass in arms and legs (kilograms) divided by the square of height (meters). Cross-sectional and longitudinal (6-year) associations of low ASM (bottom 25 % AAH sample; ASM with limited mobility (4-m gait walk ≤1 m/s or 6-min walk ASM with limited mobility was associated with IADL difficulties (p = .008) and frailty (p = .040) but not with ADL difficulties or falls in cross-sectional analyses; and with ADL difficulties (p = .022), IADL difficulties (p = .006), frailty (p = .039), and mortality (p = .003) but not with falls in longitudinal analyses adjusted for age and gender. Low ASM alone was marginally associated with mortality (p = .085) but not with other outcomes in cross-sectional or longitudinal analyses. Low ASM with limited mobility is associated with poor health outcomes among late middle-aged African Americans.

  18. 3D automatic anatomy segmentation based on iterative graph-cut-ASM

    International Nuclear Information System (INIS)

    Chen, Xinjian; Bagci, Ulas

    2011-01-01

    Purpose: This paper studies the feasibility of developing an automatic anatomy segmentation (AAS) system in clinical radiology and demonstrates its operation on clinical 3D images. Methods: The AAS system, the authors are developing consists of two main parts: object recognition and object delineation. As for recognition, a hierarchical 3D scale-based multiobject method is used for the multiobject recognition task, which incorporates intensity weighted ball-scale (b-scale) information into the active shape model (ASM). For object delineation, an iterative graph-cut-ASM (IGCASM) algorithm is proposed, which effectively combines the rich statistical shape information embodied in ASM with the globally optimal delineation capability of the GC method. The presented IGCASM algorithm is a 3D generalization of the 2D GC-ASM method that they proposed previously in Chen et al.[Proc. SPIE, 7259, 72590C1-72590C-8 (2009)]. The proposed methods are tested on two datasets comprised of images obtained from 20 patients (10 male and 10 female) of clinical abdominal CT scans, and 11 foot magnetic resonance imaging (MRI) scans. The test is for four organs (liver, left and right kidneys, and spleen) segmentation, five foot bones (calcaneus, tibia, cuboid, talus, and navicular). The recognition and delineation accuracies were evaluated separately. The recognition accuracy was evaluated in terms of translation, rotation, and scale (size) error. The delineation accuracy was evaluated in terms of true and false positive volume fractions (TPVF, FPVF). The efficiency of the delineation method was also evaluated on an Intel Pentium IV PC with a 3.4 GHZ CPU machine. Results: The recognition accuracies in terms of translation, rotation, and scale error over all organs are about 8 mm, 10 deg. and 0.03, and over all foot bones are about 3.5709 mm, 0.35 deg. and 0.025, respectively. The accuracy of delineation over all organs for all subjects as expressed in TPVF and FPVF is 93.01% and 0.22%, and

  19. 3D automatic anatomy segmentation based on iterative graph-cut-ASM.

    Science.gov (United States)

    Chen, Xinjian; Bagci, Ulas

    2011-08-01

    This paper studies the feasibility of developing an automatic anatomy segmentation (AAS) system in clinical radiology and demonstrates its operation on clinical 3D images. The AAS system, the authors are developing consists of two main parts: object recognition and object delineation. As for recognition, a hierarchical 3D scale-based multiobject method is used for the multiobject recognition task, which incorporates intensity weighted ball-scale (b-scale) information into the active shape model (ASM). For object delineation, an iterative graph-cut-ASM (IGCASM) algorithm is proposed, which effectively combines the rich statistical shape information embodied in ASM with the globally optimal delineation capability of the GC method. The presented IGCASM algorithm is a 3D generalization of the 2D GC-ASM method that they proposed previously in Chen et al. [Proc. SPIE, 7259, 72590C1-72590C-8 (2009)]. The proposed methods are tested on two datasets comprised of images obtained from 20 patients (10 male and 10 female) of clinical abdominal CT scans, and 11 foot magnetic resonance imaging (MRI) scans. The test is for four organs (liver, left and right kidneys, and spleen) segmentation, five foot bones (calcaneus, tibia, cuboid, talus, and navicular). The recognition and delineation accuracies were evaluated separately. The recognition accuracy was evaluated in terms of translation, rotation, and scale (size) error. The delineation accuracy was evaluated in terms of true and false positive volume fractions (TPVF, FPVF). The efficiency of the delineation method was also evaluated on an Intel Pentium IV PC with a 3.4 GHZ CPU machine. The recognition accuracies in terms of translation, rotation, and scale error over all organs are about 8 mm, 10 degrees and 0.03, and over all foot bones are about 3.5709 mm, 0.35 degrees and 0.025, respectively. The accuracy of delineation over all organs for all subjects as expressed in TPVF and FPVF is 93.01% and 0.22%, and all foot bones for

  20. Nerves and Nostalgia: Expression of Loss Among Greek Immigrants in Montreal

    Science.gov (United States)

    Lock, Margaret; Wakewich-Dunk, Pamela

    1990-01-01

    The authors interviewed first-generation Greek immigrant women in Montreal about nonspecific somatic symptoms. The concept of nevra (nerves), which was central to these discussions, was used to link environmental and psychosocial variables with distress and painful physical states. The authors discuss the cultural construction of female identity in Greece and analyze the negative effect of immigration on self-esteem, often manifested as attacks of nevra. Metaphorical concepts, such as nevra, can be used to improve physician understanding and to facilitate communication with, and enhance care of, immigrant patients. PMID:21234036

  1. Revising the diagnosis of congenital amusia with the Montreal Battery of Evaluation of Amusia

    OpenAIRE

    Pfeifer, Jasmin; Hamann, Silke

    2015-01-01

    This article presents a critical survey of the prevalent usage of the Montreal Battery of Evaluation of Amusia (MBEA; Peretz et al., 2003) to assess congenital amusia, a neuro-developmental disorder that has been claimed to be present in 4% of the population (Kalmus and Fry, 1980). It reviews and discusses the current usage of the MBEA in relation to cut-off scores, number of used subtests, manner of testing, and employed statistics, as these vary in the literature. Furthermore, data are pres...

  2. 106-17 Telemetry Standards Chapter 1

    Science.gov (United States)

    2017-07-01

    Telemetry Standards, RCC Standard 106-17 Chapter 1, July 2017 1-1 CHAPTER 1 Introduction The Telemetry Standards address the here-to-date...conventional methods, techniques, and practices affiliated with aeronautical telemetry applicable to the member RCC ranges. The first 11 chapters are...generally devoted to a different element of the telemetry system or process. Chapters 21 through 28 address the topic of network telemetry . These

  3. 46 CFR 56.60-1 - Acceptable materials and specifications (replaces 123 and Table 126.1 in ASME B31.1).

    Science.gov (United States)

    2010-10-01

    ... iron Conform to applicable American National Standards or refer to UCI-23 or UCD-23, Sec. VIII of the... acceptable iron castings are in UCI-23 and UCD-23 of section VIII of the ASME Boiler and Pressure Vessel Code... pressure temperature limitations refer to UCI-3 of section VIII of the ASME Boiler and Pressure Vessel Code...

  4. Incorporation of the concept of microbial product formation into ASM3 and the modeling of a membrane bioreactor for wastewater treatment

    Directory of Open Access Journals (Sweden)

    K. P. Oliveira-Esquerre

    2006-12-01

    Full Text Available This paper proposes a modification of ASM3 in a way that takes into account the process of production and consumption of microbial products (MPs in a submerged membrane bioreactor fed with the effluent of a particular precoagulation sedimentation unit. A comparative representation of the modeling results obtained with ASM3 and ASM1 is performed and it highlights the importance of considering the process of storage of organic substrate, including MPs, as a prior step to bacterial growth. In addition to the suspended solids and microorganisms, various soluble organic substances, which might be either undecomposed organic substances contained in the raw water or MPs, are assumed to be selectively retained within the bioreactor. The results show that the carbonaceous materials are more accurately estimated by ASM3, while ASM1 performs slightly better than ASM3 in the estimation of nitrate. The estimated MP concentration in the mixed liquor and permeate agrees with the experimental evidence, and as expected, MPs play a role in supplying organic substrate to heterotrophs in both ASM1 and ASM3.

  5. 46 CFR 54.01-2 - Adoption of division 1 of section VIII of the ASME Boiler and Pressure Vessel Code.

    Science.gov (United States)

    2010-10-01

    ... Boiler and Pressure Vessel Code. 54.01-2 Section 54.01-2 Shipping COAST GUARD, DEPARTMENT OF HOMELAND... division 1 of section VIII of the ASME Boiler and Pressure Vessel Code. (a) Pressure vessels shall be designed, constructed, and inspected in accordance with section VIII of the ASME Boiler and Pressure Vessel...

  6. Interaction between endoplasmic/sarcoplasmic reticulum stress (ER/SR stress), mitochondrial signaling and Ca(2+) regulation in airway smooth muscle (ASM).

    Science.gov (United States)

    Delmotte, Philippe; Sieck, Gary C

    2015-02-01

    Airway inflammation is a key aspect of diseases such as asthma. Several inflammatory cytokines (e.g., TNFα and IL-13) increase cytosolic Ca(2+) ([Ca(2+)]cyt) responses to agonist stimulation and Ca(2+) sensitivity of force generation, thereby enhancing airway smooth muscle (ASM) contractility (hyper-reactive state). Inflammation also induces ASM proliferation and remodeling (synthetic state). In normal ASM, the transient elevation of [Ca(2+)]cyt induced by agonists leads to a transient increase in mitochondrial Ca(2+) ([Ca(2+)]mito) that may be important in matching ATP production with ATP consumption. In human ASM (hASM) exposed to TNFα and IL-13, the transient increase in [Ca(2+)]mito is blunted despite enhanced [Ca(2+)]cyt responses. We also found that TNFα and IL-13 induce reactive oxidant species (ROS) formation and endoplasmic/sarcoplasmic reticulum (ER/SR) stress (unfolded protein response) in hASM. ER/SR stress in hASM is associated with disruption of mitochondrial coupling with the ER/SR membrane, which relates to reduced mitofusin 2 (Mfn2) expression. Thus, in hASM it appears that TNFα and IL-13 result in ROS formation leading to ER/SR stress, reduced Mfn2 expression, disruption of mitochondrion-ER/SR coupling, decreased mitochondrial Ca(2+) buffering, mitochondrial fragmentation, and increased cell proliferation.

  7. Chemical Tracer Methods: Chapter 7

    Science.gov (United States)

    Healy, Richard W.

    2017-01-01

    Tracers have a wide variety of uses in hydrologic studies: providing quantitative or qualitative estimates of recharge, identifying sources of recharge, providing information on velocities and travel times of water movement, assessing the importance of preferential flow paths, providing information on hydrodynamic dispersion, and providing data for calibration of water flow and solute-transport models (Walker, 1998; Cook and Herczeg, 2000; Scanlon et al., 2002b). Tracers generally are ions, isotopes, or gases that move with water and that can be detected in the atmosphere, in surface waters, and in the subsurface. Heat also is transported by water; therefore, temperatures can be used to trace water movement. This chapter focuses on the use of chemical and isotopic tracers in the subsurface to estimate recharge. Tracer use in surface-water studies to determine groundwater discharge to streams is addressed in Chapter 4; the use of temperature as a tracer is described in Chapter 8.Following the nomenclature of Scanlon et al. (2002b), tracers are grouped into three categories: natural environmental tracers, historical tracers, and applied tracers. Natural environmental tracers are those that are transported to or created within the atmosphere under natural processes; these tracers are carried to the Earth’s surface as wet or dry atmospheric deposition. The most commonly used natural environmental tracer is chloride (Cl) (Allison and Hughes, 1978). Ocean water, through the process of evaporation, is the primary source of atmospheric Cl. Other tracers in this category include chlorine-36 (36Cl) and tritium (3H); these two isotopes are produced naturally in the Earth’s atmosphere; however, there are additional anthropogenic sources of them.

  8. Fourier Transform Methods. Chapter 4

    Science.gov (United States)

    Kaplan, Simon G.; Quijada, Manuel A.

    2015-01-01

    This chapter describes the use of Fourier transform spectrometers (FTS) for accurate spectrophotometry over a wide spectral range. After a brief exposition of the basic concepts of FTS operation, we discuss instrument designs and their advantages and disadvantages relative to dispersive spectrometers. We then examine how common sources of error in spectrophotometry manifest themselves when using an FTS and ways to reduce the magnitude of these errors. Examples are given of applications to both basic and derived spectrophotometric quantities. Finally, we give recommendations for choosing the right instrument for a specific application, and how to ensure the accuracy of the measurement results..

  9. Chapter 9. The landscape sector

    International Nuclear Information System (INIS)

    Larivaille, Pierrette

    1980-01-01

    The object of this work is to examine the interactions between the activities of the electric industry (generating, transmission and distribution) and the environment, whilst showing to what extent the facilities are likely to affect it adversely and describing the measures taken to lessen the detrimental effects. The chapter devoted to the 'landscape' includes a section covering the electricity generating facilities, and among these, the nuclear power stations. The studies carried out on the main units of insertion into the site are presented, particularly the landscaping involved in setting up a power station [fr

  10. Development of a software for the ASME code qualification of class-I nuclear piping systems

    International Nuclear Information System (INIS)

    Mishra, Rajesh; Umashankar, C.; Soni, R.S.; Kushwaha, H.S.; Venkat Raj, V.

    1999-11-01

    In nuclear industry, the designer often comes across the requirements of Class-1 piping systems which need to be qualified for various normal and abnormal loading conditions. In order to have quick design changes and the design reviews at various stages of design, it is quite helpful if a dedicated software is available for the qualification of Class-1 piping systems. BARC has already purchased a piping analysis software CAESAR-II and has used it for the life extension of heavy water plant, Kota. CAESAR-II facilitates the qualification of Class-2 and Class-3 piping systems among others. However, the present version of CAESAR-II does not have the capability to perform stress checks for the ASME Class-1 nuclear piping systems. With this requirement in mind and the prohibitive costs of commercially available software for the Class-1 piping analyses, it was decided to develop a separate software for this class of piping in such a way that the input and output details of the piping from the CAESAR-II software can be made use of. This report principally contains the details regarding development of a software for codal qualification of Class-1 nuclear piping as per ASME code section-III, NB-3600. The entire work was carried out in three phases. The first phase consisted of development of the routines for reading the output files obtained from the CAESAR-II software, and converting them into required format for further processing. In this phase, the nodewise informations available from the CAESAR-II output file were converted into element-wise informations. The second phase was to develop a general subroutine for reading the various input parameters such as diameter, wall thickness, corrosion allowance, bend radius and also to recognize the bend elements based on the bend radius, directly from the input file of CAESAR-II software. The third phase was regarding the incorporation of the required steps for performing the ASME codal checks as per NB-3600 for Class-1 piping

  11. Code-Switching among Trilingual Montrealers: French, English and a Heritage Language

    Directory of Open Access Journals (Sweden)

    Ephie Konidaris

    2004-01-01

    Full Text Available 'Ibis study focuses on the concept of code-switching, which can be defined as the verbal strategy by which multilingual speakers change linguistic code(s within the same speech event as a sign of cultural solidarity or distance and as an act of cultural identity. The participants partaking in this study are three trilingual persons living and working in Montreal. They possess linguistic competencies in the following three languages: English, French and Greek. This study is of particular interest due to the complexity of the socio-political, ethnic, and linguistic context of the setting which entails bilinguality (English and French according to Canada's language laws, while Quebec's provincial laws profess to only one official language (French. In addition, the anecdotal fact that heritage languages of certain minority groups are maintained and widely utilized by members of the specific group in Montreal adds to the unique context in which the trilingual participants were brought up, and that in which they currently live. This study consists of an analysis of the codes (and code-switches used in the participants' audio-taped conversation, obtained as data with consent and later transcribed for analysis.

  12. Protestants, Catholics, and Masonic Conspiracies: The British Association in Montreal (1884).

    Science.gov (United States)

    Toal, Ciaran

    2016-03-01

    The British Association for the Advancement of Science (BAAS), like many nineteenth-century institutions, sought to avoid controversy by excluding the discussion of political and religious topics from its proceedings. Nonpartisanship was a veneer it could hide behind. Yet during the Montreal meeting of 1884-the first time the association ventured beyond the comfortable confines of the British Isles-this "middle way" was tested. While local and visiting Anglophones, many of them BAAS members, viewed the proceedings and character of the association as "decidedly friendly" to religion and as promoting the broad interests of Protestants, Montreal's episcopacy and French-speaking press rallied against the anti-Catholic BAAS, accusing it of harboring a dangerous Masonic clique. In different material and social spaces, the relationship between science, religion, and the association was conceived in distinct ways. In examining this case, this essay seeks to augment the growing body of scholarship within science studies that recognizes the importance of writing both the history and the geography of encounters between science and religion.

  13. Chapter 11: Concentrating Solar Power

    Energy Technology Data Exchange (ETDEWEB)

    Turchi, Craig S [National Renewable Energy Laboratory (NREL), Golden, CO (United States); Stekli, J. [U.S. Department of Energy; Bueno, P. C. [Southwest Research Institute

    2017-01-02

    This chapter summarizes the applications of the supercritical CO2 (sCO2) Brayton cycle in concentrating solar power (CSP) plants. The design and operation of CSP plants are reviewed to highlight the requirements for the power cycle and attributes that are advantageous for the solar-thermal application. The sCO2 Brayton cycle offers the potential of higher cycle efficiency versus superheated or supercritical steam cycles at temperatures relevant for CSP applications. In addition, Brayton cycle systems using sCO2 are anticipated to have smaller weight and volume, lower thermal mass, and less complex power blocks compared with Rankine cycles due to the higher density of the fluid and simpler cycle design. The simpler machinery and compact size of the sCO2 process may also reduce the installation, maintenance, and operation cost of the system. Power cycle capacities in the range of 10-150 MWe are anticipated for the CSP application. In this chapter, we explore sCO2 Brayton cycle configurations that have attributes that are desirable from the perspective of a CSP application, such as the ability to accommodate dry cooling and daily cycling, as well as integration with thermal energy storage.

  14. Impact of the A18.1 ASME Standard on Platform Lifts and Stairway Chairlifts on Accessibility and Usability

    Science.gov (United States)

    Balmer, David C.

    2010-01-01

    This article summarizes the effect of the ASME A18.1 Standard concerning accessibility and usability of Platform Lifts and their remaining technological challenges. While elevators are currently the most effective means of vertical transportation related to speed, capacity, rise and usability, their major drawbacks for accessibility are cost and…

  15. Modeling Nitrous Oxide Production during Biological Nitrogen Removal via Nitrification and Denitrification: Extensions to the General ASM Models

    DEFF Research Database (Denmark)

    Ni, Bing-Jie; Ruscalleda, Maël; Pellicer i Nàcher, Carles

    2011-01-01

    Nitrous oxide (N2O) can be formed during biological nitrogen (N) removal processes. In this work, a mathematical model is developed that describes N2O production and consumption during activated sludge nitrification and denitrification. The well-known ASM process models are extended to capture N2O...

  16. Simulation of municipal-industrial full scale WWTP in an arid climate by application of ASM3

    Directory of Open Access Journals (Sweden)

    Abdelsalam Elawwad

    2017-03-01

    Full Text Available In developing countries, and due to the high cost of treatment of industrial wastewater, municipal wastewater treatment facilities usually receive a mixture of municipal wastewater and partially treated industrial wastewater. As a result, an increased potential for shock loads with high pollutant concentrations is expected. The use of mathematical modelling of wastewater treatment is highly efficient in such cases. A dynamic model based on activated sludge model no. 3 (ASM3 describing the performance of the activated sludge process at a full scale wastewater treatment plant (WWTP receiving mixed domestic–industrial wastewater located in an arid area is presented. ASM3 was extended by adding the Arrhenius equation to respond to changes in temperature. BioWin software V.4 was used as the model platform. The model was calibrated under steady-state conditions, adjusting only three kinetic and stoichiometric parameters: maximum heterotrophic growth rate (μH = 8 d−1, heterotrophic aerobic decay rate (bH, O2 = 0.18 d−1, and aerobic heterotrophic yield (YH,O2 = 0.4 (gCOD/gCOD. ASM3 was successful in predicting the WWTP performance, as the model was validated with 10 months of routine daily measurements. ASM3 extended with the Arrhenius equation could be helpful in the design and operation of WWTPs with mixed municipal–industrial influent in arid areas.

  17. Flanged joints with contact outside the bolt circle: ASME Part B design rules

    International Nuclear Information System (INIS)

    Rodabaugh, E.C.; Moore, S.E.

    1976-05-01

    The ASME Boiler and Pressure Vessel Code, Section VIII, Division 1, gives rules which are subdivided into ''Part A'' and ''Part B''. Part A covers flanged joints where contact between flanges occurs through a gasket located inside the bolt holes. Part B covers flanged joints with contact outside the bolt holes. This report (a) summarizes the theory for Part B flanged joints, (b) presents examples which show the significant differences between Part A flanged joints and Part B flanged joints, (c) presents the available test data relevant to the characteristics of Part B flanged joints, (d) gives listings of two computer programs which can be used to evaluate the characteristics of Part B flanged joints, and (e) gives recommendations for Code revisions and other aspects of Part B flanged-joint design

  18. Change of nonlinear acoustics in ASME grade 122 steel welded joint during creep

    Science.gov (United States)

    Ohtani, Toshihiro; Honma, Takumi; Ishii, Yutaka; Tabuchi, Masaaki; Hongo, Hiromichi; Hirao, Masahiko

    2016-02-01

    In this paper, we described the changes of two nonlinear acoustic characterizations; resonant frequency shift and three-wave interaction, with electromagnetic acoustic resonance (EMAR) throughout the creep life in the welded joints of ASME Grade 122, one of high Cr ferritic heat resisting steels. EMAR was a combination of the resonant acoustic technique with a non-contact electromagnetic acoustic transducer (EMAT). These nonlinear acoustic parameters decreased from the start to 50% of creep life. After slightly increased, they rapidly increased from 80% of creep life to rupture. We interpreted these phenomena in terms of dislocation recovery, recrystallization, and restructuring related to the initiation and growth of creep void, with support from the SEM and TEM observation.

  19. ASME B89.4.19 Performance Evaluation Tests and Geometric Misalignments in Laser Trackers.

    Science.gov (United States)

    Muralikrishnan, B; Sawyer, D; Blackburn, C; Phillips, S; Borchardt, B; Estler, W T

    2009-01-01

    Small and unintended offsets, tilts, and eccentricity of the mechanical and optical components in laser trackers introduce systematic errors in the measured spherical coordinates (angles and range readings) and possibly in the calculated lengths of reference artifacts. It is desirable that the tests described in the ASME B89.4.19 Standard [1] be sensitive to these geometric misalignments so that any resulting systematic errors are identified during performance evaluation. In this paper, we present some analysis, using error models and numerical simulation, of the sensitivity of the length measurement system tests and two-face system tests in the B89.4.19 Standard to misalignments in laser trackers. We highlight key attributes of the testing strategy adopted in the Standard and propose new length measurement system tests that demonstrate improved sensitivity to some misalignments. Experimental results with a tracker that is not properly error corrected for the effects of the misalignments validate claims regarding the proposed new length tests.

  20. Technical Review on Fitness-for-Service for Buried Pipe by ASME Code Case N-806

    International Nuclear Information System (INIS)

    Park, Sang Kyu; Lee, Yo Seop; So, Il Su; Lim, Bu Taek

    2012-01-01

    Fitness-for-Service is a useful technology to determine replacement timing, next inspection timing or in-service when nuclear power plant's buried pipes are damaged. If is possible for buried pipes to be aged by material loss, cracks and occlusion as operating time goes by. Therefore Fitness-for-Service technology for buried pipe is useful for plant industry to perform replacement and repair. Fitness-for-Service for buried pipe is studied in terms of existing code and standard for Fitness-for-Service and a current developing code case. Fitness-for-Service for buried pipe was performed according to Code Case N-806 developed by ASME (American Society of Mechanical Engineers)

  1. Linearization in ASM1 model for the solution of pollutants transport equations

    Directory of Open Access Journals (Sweden)

    Neyva Maria Lopes Romeiro

    2008-08-01

    Full Text Available It is proposed to reduce the complexity existing in non-linear BIOMOC and ASM1 models using Taylor’s frst-order series expansion in the terms whose reactive processes are non-linear. One of the advantages of linear models is the conservation of non-linear model variables. However, the main characteristic of this methodology refers to the computational time obtained in the numeral simulations, which is much shorter than that concerning the non-linear model results. Numerical results are presented, showing the effciency, precision and solidity of the proposed technique in well-known cases in the literature, using the semi-discrete method of finite elements.

  2. Nupack, the new Asme code for radioactive material transportation packaging containments

    International Nuclear Information System (INIS)

    Turula, P.

    1998-01-01

    The American Society of Mechanical Engineers (ASME) has added a new division to the nuclear construction section of its Boiler and Pressure Vessel Code (B and PVC). This Division, commonly referred to as 'Nupack', has been written to provide a consistent set of technical requirements for containment vessels of transportation packagings for high-level radioactive materials. This paper provides an introduction to Nupack, discusses some of its technical provisions, and describes how it can be used the design and construction of packaging components. Nupack's general provisions and design requirements are emphasized, while treatment of materials, fabrication and inspection is left for another paper. Participation in the Nupack development work described in this paper was supported by the U.S. Department of Energy. (authors)

  3. ASME power test code ptc 4.1 for steam generators; Codigo de pruebas de potencia ASME ptc 4.1 para generadores de vapor

    Energy Technology Data Exchange (ETDEWEB)

    Plauchu Alcantara, Jorge Alberto [Plauchu Consultores, Morelia, Michoacan (Mexico)

    2001-07-01

    This presentation is oriented towards those who in this subject have experience in the design and equipment specification, plant projects, factory and field testing, operation or result analyses. An important fraction of the national energy supply, approximately 13%, is applied to the steam generation in the different aspects of the industrial activity, in the electrical industry of public service and in the commercial and services sector. The development of the national programs of energy efficiency verifies this when dedicating to this use of the energy important projects, some of them with support of the USAID. The measurement of the energy utilization or the efficiency of steam generators (or boilers) is made applying some procedure agreed by the parts and the one of greater acceptance and best known in Mexico and internationally is the ASME Power Test Code PTC 4.1 for Steam Generators. The purpose and formality in the determination of efficiency and of steam generation capacity behavior, thermal basic regime or fulfillment of guarantees, radically changes the exigencies of strict attachment to the PTC 4.1 This definition will determine the importance of the test method selected, the deviations and convened exceptions, the influence of the precision and the measurement errors, the consideration of auxiliary equipment, etc. An interpretation or incorrect application of the Test Code has lead and will lead to results and nonreliable decisions. [Spanish] Esta exposicion se orienta a quienes en este tema cuenta con experiencia en diseno y especificacion de equipo, proyecto de planta, pruebas en fabrica y campo, operacion o analisis de resultados. Una fraccion importante de la oferta nacional de energia, 13% aproximadamente, se aplica a la generacion de vapor en diferentes giros de actividad industrial, en la industria electrica, de servicio publico y en el sector de servicios y comercial. El desarrollo de los programas nacionales de eficiencia energetica comprueba

  4. Solar water heating at Ikea's Montreal store; Chauffage solaire de l'eau courante au magasin Ikea de Montreal

    Energy Technology Data Exchange (ETDEWEB)

    Lagana, A.; Sonmor, K. [Ecovision experts-conseils inc., Montreal, PQ (Canada)

    2010-01-01

    The Ikea store in Montreal has integrated an energy efficient solar water heater into its building infrastructure. In June 2010, 30 fixed solar panels were installed on the roof to recuperate energy from the sun for hot water use in the restaurant and store facilities. Prior to this installation, the store was using natural gas for water heating purposes. During a sunny summer day, the solar water heater can provide 100 percent of the hot water needs of the store, even though it was designed to provide only one-third of the heating requirements. The panels are made of copper and painted with black titanium paint. A solution of water and antifreeze circulates in the panels. Digital controls are used at the pumps to control the temperature. The Ikea store uses approximately 3,100 gallons of water per day. The panels provide more than 60 MWh of energy, and represent a savings of 8440 cubic metres of natural gas, and a savings of 19.7 tons of carbon dioxide. The panels cost $1,300 and the return on investment is estimated to be 15.6 years. 3 figs.

  5. Using ASM Podcasts to Excite Undergraduate Students about Current Microbiological Research

    Directory of Open Access Journals (Sweden)

    Stacey E. Lettini

    2014-08-01

    Full Text Available Innovative technology is often used as a mechanism to engage students in and out of the classroom and can be used to increase critical thinking skills. Podcasts are an excellent way to introduce students to current topics and research in microbiology. The American Society for Microbiology (ASM produces three podcasts that are microbiologically focused: This Week in Microbiology (TWiM, This Week in Parasitology (TWiP, and This Week in Virology (TWiV. These podcasts are usually presented in a manner similar to a journal club, as the presenters regularly invite guests to discuss current research papers. Since students often find reading scientific literature difficult and get bogged down in the details rather than seeing the over-arching purpose of a paper, these podcasts have been used in a General Microbiology course to introduce recent research articles. The students were first assigned an original research article to read and review, and they were asked to generate questions pertaining to things they did not understand. Next, students listened to the corresponding podcast that discussed the article and used it to answer their questions. This was followed by a classroom discussion of the article and the podcast. The ASM podcast helped to demystify original research by providing details of the experimental design and presentation of the results in a language that is more casual and relatable. Students demonstrated greater critical thinking and comprehension of microbiology literature after listening to the podcast. This activity can be used in a variety of courses in the biology curriculum.

  6. ASME stress linearization and classification - a discussion based on a case study

    International Nuclear Information System (INIS)

    Miranda, Carlos A. de J.; Faloppa, Altair A.; Mattar Neto, Miguel; Fainer, Gerson

    2011-01-01

    The ASME code, specially in its Nuclear Division (Subsection NB - Class I Components), gives some recommendations to the structural analyst on how to perform the verifications required to prove the design as good as the by-analysis prevented failures modes. Each of these failure modes has specific stress limits which are established based on simple but conservative hypothesis like the material perfectly plastic behavior and the shell theory with its typical membrane and bending stresses with linear distribution along the thickness. Other detail to keep in mind is the code distinction between primary and secondary stresses (respectively, stress that came due to equilibrium and due to displacement compatibility). In general, the numerical models used in the analyses are developed with plane or 3D solid elements and due this fact no direct comparison with the code limits can be done and, besides that, the programs do not distinguish between primary and secondary stresses. Mostly, the later are produced due to the temperature variation but they also appear near discontinuities. Sometimes, this classification is not so clear or direct. To perform the required ASME Code verifications the analyst should obtain the membrane and bending stresses from the plane or 3-D model which is called stress linearization and, also, should classify them as primary and secondary. (The excess between the maximum stress at a point and the sum of these linearized values is called peak stress and is included in the fatigue verification.) This task, most of the time is not a simple one due to the nature of the involved load and/or the complex geometry under analysis. In fact, there are several studies discussing on how to perform these stress classification and linearization. The present paper shows a discussion on how to perform these verifications based on a generic geometry found in many plants, from petrochemical to nuclear, which emphasizes some of theses issues. (author)

  7. User-inspired design methodology using Affordance Structure Matrix (ASM for construction projects

    Directory of Open Access Journals (Sweden)

    Maheswari J. Uma

    2017-01-01

    Full Text Available Traditionally, design phase of construction projects is often performed with incomplete and inaccurate user preferences. This is due to inefficiencies in the methodologies used for capturing the user requirements that can subsequently lead to inconsistencies and result in non-optimised end-result. Iterations and subsequent reworks due to such design inefficiencies is one of the major reasons for unsuccessful project delivery as they impact project performance measures such as time and cost among others. The existing design theories and practice are primarily based on functional requirements. Function-based design deals with design of artifact alone, which may yield favourable or unfavourable consequences with the design artifact. However, incorporating other interactions such as interactions between user & designer is necessary for optimised end-result. Hence, the objective of this research work is to devise a systematic design methodology considering all the three interactions among users, designers and artefacts for improved design efficiency. In this study, it has been attempted to apply the theory of affordances in a case project that involves the design of an offshore facility. A step-by-step methodology for developing Affordance Structure Matrix (ASM, which integrates House of Quality (HOQ and Design Structure Matrix (DSM, is proposed that can effectively capture the user requirements. HOQ is a popular quality management tool for capturing client requirements and DSM is a matrix-based tool that can capture the interdependency among the design entities. The proposed methodology utilises the strengths of both the tools, as DSM compliments HOQ in the process. In this methodology, different affordances such as AUA (Artifact-User-Affordance, AAA (Artifact-Artifact-Affordance and DDA (Designer-Designer-Affordance are captured systematically. Affordance is considered to be user-driven in this context that is in contrast to prevailing design

  8. Comparative evaluation of structural integrity for ITER blanket shield block based on SDC-IC and ASME code

    Energy Technology Data Exchange (ETDEWEB)

    Shim, Hee-Jin [ITER Korea, National Fusion Research Institute, 169-148 Gwahak-Ro, Yuseong-Gu, Daejeon (Korea, Republic of); Ha, Min-Su, E-mail: msha12@nfri.re.kr [ITER Korea, National Fusion Research Institute, 169-148 Gwahak-Ro, Yuseong-Gu, Daejeon (Korea, Republic of); Kim, Sa-Woong; Jung, Hun-Chea [ITER Korea, National Fusion Research Institute, 169-148 Gwahak-Ro, Yuseong-Gu, Daejeon (Korea, Republic of); Kim, Duck-Hoi [ITER Organization, Route de Vinon sur Verdon - CS 90046, 13067 Sant Paul Lez Durance (France)

    2016-11-01

    Highlights: • The procedure of structural integrity and fatigue assessment was described. • Case studies were performed according to both SDC-IC and ASME Sec. • III codes The conservatism of the ASME code was demonstrated. • The study only covers the specifically comparable case about fatigue usage factor. - Abstract: The ITER blanket Shield Block is a bulk structure to absorb radiation and to provide thermal shielding to vacuum vessel and external vessel components, therefore the most significant load for Shield Block is the thermal load. In the previous study, the thermo-mechanical analysis has been performed under the inductive operation as representative loading condition. And the fatigue evaluations were conducted to assure structural integrity for Shield Block according to Structural Design Criteria for In-vessel Components (SDC-IC) which provided by ITER Organization (IO) based on the code of RCC-MR. Generally, ASME code (especially, B&PV Sec. III) is widely applied for design of nuclear components, and is usually well known as more conservative than other specific codes. For the view point of the fatigue assessment, ASME code is very conservative compared with SDC-IC in terms of the reflected K{sub e} factor, design fatigue curve and other factors. Therefore, an accurate fatigue assessment comparison is needed to measure of conservatism. The purpose of this study is to provide the fatigue usage comparison resulting from the specified operating conditions shall be evaluated for Shield Block based on both SDC-IC and ASME code, and to discuss the conservatism of the results.

  9. Verification of Allowable Stresses In ASME Section III Subsection NH For Grade 91 Steel & Alloy 800H

    Energy Technology Data Exchange (ETDEWEB)

    R. W. Swindeman; M. J. Swindeman; B. W. Roberts; B. E. Thurgood; D. L. Marriott

    2007-11-30

    The database for the creep-rupture of 9Cr-1Mo-V (Grade 91) steel was collected and reviewed to determine if it met the needs for recommending time-dependent strength values, S{sub t}, for coverage in ASME Section III Subsection NH (ASME III-NH) to 650 C (1200 F) and 600,000 hours. The accumulated database included over 300 tests for 1% total strain, nearly 400 tests for tertiary creep, and nearly 1700 tests to rupture. Procedures for analyzing creep and rupture data for ASME III-NH were reviewed and compared to the procedures used to develop the current allowable stress values for Gr 91 for ASME II-D. The criteria in ASME III-NH for estimating S{sub t} included the average strength for 1% total strain for times to 600,000 hours, 80% of the minimum strength for tertiary creep for times to 600,000 hours, and 67% of the minimum rupture strength values for times to 600,000 hours. Time-temperature-stress parametric formulations were selected to correlate the data and make predictions of the long-time strength. It was found that the stress corresponding to 1% total strain and the initiation of tertiary creep were not the controlling criteria over the temperature-time range of concern. It was found that small adjustments to the current values in III-NH could be introduced but that the existing values were conservative and could be retained. The existing database was found to be adequate to extend the coverage to 600,000 hours for temperatures below 650 C (1200 F).

  10. Corticosteroid-Induced MKP-1 Represses Pro-Inflammatory Cytokine Secretion by Enhancing Activity of Tristetraprolin (TTP) in ASM Cells.

    Science.gov (United States)

    Prabhala, Pavan; Bunge, Kristin; Ge, Qi; Ammit, Alaina J

    2016-10-01

    Exaggerated cytokine secretion drives pathogenesis of a number of chronic inflammatory diseases, including asthma. Anti-inflammatory pharmacotherapies, including corticosteroids, are front-line therapies and although they have proven clinical utility, the molecular mechanisms responsible for their actions are not fully understood. The corticosteroid-inducible gene, mitogen-activated protein kinase (MAPK) phosphatase 1 (MKP-1, DUSP1) has emerged as a key molecule responsible for the repressive effects of steroids. MKP-1 is known to deactivate p38 MAPK phosphorylation and can control the expression and activity of the mRNA destabilizing protein-tristetraprolin (TTP). But whether corticosteroid-induced MKP-1 acts via p38 MAPK-mediated modulation of TTP function in a pivotal airway cell type, airway smooth muscle (ASM), was unknown. While pretreatment of ASM cells with the corticosteroid dexamethasone (preventative protocol) is known to reduce ASM synthetic function in vitro, the impact of adding dexamethasone after stimulation (therapeutic protocol) had not been explored. Whether dexamethasone modulates TTP in a p38 MAPK-dependent manner in this cell type was also unknown. We address this herein and utilize an in vitro model of asthmatic inflammation where ASM cells were stimulated with the pro-asthmatic cytokine tumor necrosis factor (TNF) and the impact of adding dexamethasone 1 h after stimulation assessed. IL-6 mRNA expression and protein secretion was significantly repressed by dexamethasone acting in a temporally distinct manner to increase MKP-1, deactivate p38 MAPK, and modulate TTP phosphorylation status. In this way, dexamethasone-induced MKP-1 acts via p38 MAPK to switch on the mRNA destabilizing function of TTP to repress pro-inflammatory cytokine secretion from ASM cells. J. Cell. Physiol. 231: 2153-2158, 2016. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  11. Spectrum of SMPD1 mutations in Asian-Indian patients with acid sphingomyelinase (ASM)-deficient Niemann-Pick disease.

    Science.gov (United States)

    Ranganath, Prajnya; Matta, Divya; Bhavani, Gandham SriLakshmi; Wangnekar, Savita; Jain, Jamal Mohammed Nurul; Verma, Ishwar C; Kabra, Madhulika; Puri, Ratna Dua; Danda, Sumita; Gupta, Neerja; Girisha, Katta M; Sankar, Vaikom H; Patil, Siddaramappa J; Ramadevi, Akella Radha; Bhat, Meenakshi; Gowrishankar, Kalpana; Mandal, Kausik; Aggarwal, Shagun; Tamhankar, Parag Mohan; Tilak, Preetha; Phadke, Shubha R; Dalal, Ashwin

    2016-10-01

    Acid sphingomyelinase (ASM)-deficient Niemann-Pick disease is an autosomal recessive lysosomal storage disorder caused by biallelic mutations in the SMPD1 gene. To date, around 185 mutations have been reported in patients with ASM-deficient NPD world-wide, but the mutation spectrum of this disease in India has not yet been reported. The aim of this study was to ascertain the mutation profile in Indian patients with ASM-deficient NPD. We sequenced SMPD1 in 60 unrelated families affected with ASM-deficient NPD. A total of 45 distinct pathogenic sequence variants were found, of which 14 were known and 31 were novel. The variants included 30 missense, 4 nonsense, and 9 frameshift (7 single base deletions and 2 single base insertions) mutations, 1 indel, and 1 intronic duplication. The pathogenicity of the novel mutations was inferred with the help of the mutation prediction software MutationTaster, SIFT, Polyphen-2, PROVEAN, and HANSA. The effects of the identified sequence variants on the protein structure were studied using the structure modeled with the help of the SWISS-MODEL workspace program. The p. (Arg542*) (c.1624C>T) mutation was the most commonly identified mutation, found in 22% (26 out of 120) of the alleles tested, but haplotype analysis for this mutation did not identify a founder effect for the Indian population. To the best of our knowledge, this is the largest study on mutation analysis of patients with ASM-deficient Niemann-Pick disease reported in literature and also the first study on the SMPD1 gene mutation spectrum in India. © 2016 Wiley Periodicals, Inc. © 2016 Wiley Periodicals, Inc.

  12. Why Radiotherapy Works. Chapter 6

    International Nuclear Information System (INIS)

    Tashiro, S.; Nishibuchi, I.; Wondergem, J.

    2017-01-01

    The history of radiotherapy began in 1895, when Röntgen discovered X rays, and in the following year, radiation was used for medical treatment. In the early days, the development of radiotherapy was based extensively on empiricism. Radiotherapists worked closely with radiation biologists in attempting to describe and understand the phenomena produced by ionizing radiation in the clinic and in biological systems. During the ensuing 120 years, radiotherapy has been improved significantly and, in addition to radiation biology, medical physics has played an important role in the design and development of equipment, quality assurance and dosimetry. Over recent decades, advances have been made in the field of molecular biology. Currently available techniques enable us to elucidate the molecular mechanisms of cellular response to ionizing irradiation, and it is anticipated that the role and contributions of radiation biology in radiotherapy will remain relevant. This chapter describes the clinically important biological points, including knowledge from current molecular biology.

  13. Defining groundwater age. Chapter 3

    International Nuclear Information System (INIS)

    Torgersen, T.; Purtschert, R.; Phillips, F.M.; Plummer, L.N.; Sanford, W.E.; Suckow, A.

    2013-01-01

    This book investigates applications of selected chemical and isotopic substances that can be used to recognize and interpret age information pertaining to ‘old’ groundwater (defined as water that was recharged on a timescale from approximately 1000 to more than 1 000 000 a). However, as discussed below, only estimates of the ‘age’ of water extracted from wells can be inferred. These groundwater age estimates are interpreted from measured concentrations of chemical and isotopic substances in the groundwater. Even then, there are many complicating factors, as discussed in this book. In spite of these limitations, much can be learned about the physics of groundwater flow and about the temporal aspects of groundwater systems from age interpretations of measured concentrations of environmental tracers in groundwater systems. This chapter puts the concept of ‘age’ into context, including its meaning and interpretation, and attempts to provide a unifying usage for the rest of the book.

  14. A comparison of the mini mental state exam to the Montreal cognitive assessment in identifying cognitive deficits in Parkinson's disease

    NARCIS (Netherlands)

    Zadikoff, Cindy; Fox, Susan H.; Tang-Wai, David F.; Thomsen, Teri; de Bie, Rob M. A.; Wadia, Pettarusup; Miyasaki, Janis; Duff-Canning, Sarah; Lang, Anthony E.; Marras, Connie

    2008-01-01

    Dementia is an important and increasingly recognized problem in Parkinson's disease (PD). The mini-mental state examination (MMSE) often fails to detect early cognitive decline. The Montreal cognitive assessment (MoCA) is a brief tool developed to detect mild cognitive impairment that assesses a

  15. Taking the Bull by the Horns: The Critical Perspectives and Pedagogy of Two Black Teachers in Anglophone Montreal Schools

    Science.gov (United States)

    Howard, Philip S. S.

    2014-01-01

    In the midst of the complicated racial-linguistic landscape that is Montreal, Quebec, the educational experiences of the relatively small population of Anglophone Blacks are often invisibilized within the education literature, and relatively little attention is paid to the nature of Black students' and educators' struggles with racism and…

  16. Nontimber forest products in the United States: Montreal Process indicators as measures of current conditions and sustainability

    Science.gov (United States)

    Susan J. Alexander; Sonja N. Oswalt; Marla R. Emery

    2011-01-01

    The United States, in partnership with 11 other countries, participates in the Montreal Process. Each country assesses national progress toward the sustainable management of forest resources by using a set of criteria and indicators agreed on by all member countries. Several indicators focus on nontimber forest products (NTFPs). In the United States, permit and...

  17. Time to register for the World Congress of Gastroenterology meeting in Montreal: September 10-14, 2005

    Directory of Open Access Journals (Sweden)

    Philip M Sherman

    2004-01-01

    Full Text Available By now, you should have received an announcement regarding the World Congress of Gastroenterolgy (WCOG 2005 meeting in Montreal, Quebec entitled 'Global Goals in Gastroenterology - Expanding Horizons in the 21st Century'. Enclosed with the announcement is a registration form. We have completed and sent in our forms already - and now encourage you to do the same!

  18. Proceedings of the IUFRO technical session on geomorphic hazards in managed forests: 5-11 August 1990: Montreal, Canada

    Science.gov (United States)

    Raymond M. Rice

    1991-01-01

    The proceedings contains 11 the 17 papers presented at the technical session on geometric hazards in managed forests at the XIX World Congress, International Union of Forestry Research Organizations, August 5-11, 1990, Montreal, Canada, plus one paper not presented orally. Two papers report research on torrents, two are about snow, three concern landslides, and five...

  19. 14 CFR 203.4 - Montreal Agreement as part of airline-passenger contract and conditions of carriage.

    Science.gov (United States)

    2010-01-01

    ... 14 Aeronautics and Space 4 2010-01-01 2010-01-01 false Montreal Agreement as part of airline-passenger contract and conditions of carriage. 203.4 Section 203.4 Aeronautics and Space OFFICE OF THE SECRETARY, DEPARTMENT OF TRANSPORTATION (AVIATION PROCEEDINGS) ECONOMIC REGULATIONS WAIVER OF WARSAW CONVENTION LIABILITY LIMITS AND DEFENSES § 203.4...

  20. Closeness and Competition in the Inter-Ethnic and Co-Ethnic Friendships of Early Adolescents in Toronto and Montreal

    Science.gov (United States)

    Schneider, Barry H.; Dixon, Kristopher; Udvari, Stephen

    2007-01-01

    The purpose of this study is to compare the inter-ethnic and co-ethnic friendships of 390 junior high school students in multi-ethnic neighborhoods of Montreal and Toronto. Friendship dyads were identified on the basis of reciprocal nomination as close friends. The quality of the friendships was measured by questionnaires completed by both members…

  1. Chapter 3 - At the roadside: Forest resources

    Science.gov (United States)

    Bryce Stokes; Timothy G. Rials; Leonard R. Johnson; Karen L. Abt; Prakash Nepal; Kenneth E. Skog; Robert C. Abt; Lixia He; Burton C. English

    2016-01-01

    Chapter 3 assesses the availability of forest resources to the roadside. Not all woody feedstocks are discussed in this chapter. Logging residues and wholetree biomass are included. Other feedstock categories have been moved to chapter 5 or are redefined to be included in the whole-tree biomass category. New methodologies and data are used in the assessment to

  2. Required internship in diagnostic radiology in the fifth year of medicine at Montreal University

    International Nuclear Information System (INIS)

    Saint-Georges, G.; Raymond-Tremblay, D.; Danais, S.; Dussault, R.; Grignon, A.; Lafortune, M.; Saltiel, J.

    1984-01-01

    Problems of methodology, organization, and evaluation confronting the radiology departments of the university hospitals affiliated with the University of Montreal, the medical students, and the University itself in connection with an elective internship in radiology offered in the fifth year of medicine, resulted in the formation of a committee to reorganize the course of study. In this concise article the authors describe this and other measures taken by the University to solve these problems. The committees' main purpose was to restructure the internship which was made compulsory so that future physicians would be prepared to draw on the resources of diagnostic radiology and nuclear medicine. To this end, the committee formulated the objectives, content, evaluation system, and pedagogical methods to be used in those courses. The 25 self-teaching modules, together with the observation and practical interpretation of radiology sessions, proved highly useful in solving the initial problems, and were of particular interest to the students. (author)

  3. Bank of Montreal v. Dynex Petroleum Ltd.: the priority of overriding royalties and net profit interests

    International Nuclear Information System (INIS)

    Dearlove, F.R.

    1996-01-01

    The practice by the petroleum industry of granting overriding royalties (ORRs) and net profit interests (NPIs), was discussed. Some of the reasons for granting ORRs or NPIs included: (1) securing a lease, (2) obtaining geological information, (3) a condition of employment, or (4) acceptance of risk in exploration. In the recent case of Bank of Montreal versus Dynex Petroleum Ltd., it was held that in Alberta, ORRs and NPIs issuing out of a lessee's interest in an oil and gas lease cannot be a grant of interest in land. The effect of this decision is that it will make it difficult to create an ORR or NPI that is not merely a contract. An appeal is expected

  4. Flux measurements in the LEU refueled Slowpoke-2 reactor of Ecole Polytechnique de Montreal

    Energy Technology Data Exchange (ETDEWEB)

    EL Hajjaji, O.; Kennedy, G.; Rozon, D. [Ecole Polytechnique de Montreal, Quebec (Canada). Institut de Genie Nucleaire]. E-mail: elhajj@meca.polymtl.ca

    1998-07-01

    The HEU (93%) SLOWPOKE-2 reactor of Ecole Polytechnique de Montreal was refueled in September 1997 with (20%) LEU fuel after twenty years of operation. Upon completion of refueling the thermal and epithermal neutron fluxes were measured at four radii in the new core by irradiating gold and copper wire at 20 W for 10 minutes. These flux profiles were normalized to the values measured in an irradiation site in the beryllium reflector. We have also used the DRAGON/DONJON chain of codes and a detailed SLOWPOKE reactor model to calculate the flux distribution in the core and in the irradiation site. The calculated flux profiles along the four vertical lines are in agreement with the experimental values. This work also enable us to validate our codes, normally used for power reactors, for a low power research reactor. (author)

  5. Flux measurements in the LEU refueled Slowpoke-2 reactor of Ecole Polytechnique de Montreal

    International Nuclear Information System (INIS)

    EL Hajjaji, O.; Kennedy, G.; Rozon, D.

    1998-01-01

    The HEU (93%) SLOWPOKE-2 reactor of Ecole Polytechnique de Montreal was refueled in September 1997 with (20%) LEU fuel after twenty years of operation. Upon completion of refueling the thermal and epithermal neutron fluxes were measured at four radii in the new core by irradiating gold and copper wire at 20 W for 10 minutes. These flux profiles were normalized to the values measured in an irradiation site in the beryllium reflector. We have also used the DRAGON/DONJON chain of codes and a detailed SLOWPOKE reactor model to calculate the flux distribution in the core and in the irradiation site. The calculated flux profiles along the four vertical lines are in agreement with the experimental values. This work also enable us to validate our codes, normally used for power reactors, for a low power research reactor. (author)

  6. Cognitive reserve in a cross-cultural population: the case of Italian emigrants in Montreal.

    Science.gov (United States)

    Mondini, Sara; Guarino, Ramona; Jarema, Gonia; Kehayia, Eva; Nair, Vasavan; Nucci, Massimo; Mapelli, Daniela

    2014-12-01

    Cognitive reserve could be defined as the accumulation of experiences, abilities, knowledge and changes that occur throughout the lifespan. One of the most difficult changes in life is the experience of emigrating to a foreign country. The present investigation aimed to compare the cognitive reserve of two paired groups of elderly: Italians living in Italy and Italians who in adult age (around 20 years) emigrated to Montreal. Both groups attended the same years of school, in Italy. Cognitive reserve was measured in the two groups by a structured and standardised questionnaire, the cognitive reserve questionnaire. Cognitive reserve showed to be significantly higher in the Italian-Canadian individuals (i.e. Italians who emigrated). Emigration might act as an environmental factor that enriches people's lifestyle and reflects itself in the amount of their cognitive reserve.

  7. Perception of dental illness among persons receiving public assistance in Montreal.

    Science.gov (United States)

    Bedos, Christophe; Brodeur, Jean-Marc; Levine, Alissa; Richard, Lucie; Boucheron, Laurence; Mereus, Witnisse

    2005-08-01

    We examined rationales for behaviors related to dental care among persons receiving public assistance in Montreal, Quebec. Fifty-seven persons receiving public assistance participated in 8 focus groups conducted in 2002. Sessions were recorded on audiotape and transcribed; analyses included debriefing sessions and coding and interpreting transcribed data. In the absence of dental pain and any visible cavity, persons receiving public assistance believed they were free of dental illness. However, they knew that dental pain signals a pathological process that progressively leads to tooth decay and, therefore, should be treated by a dentist. However, when in pain, despite recognizing that they needed professional treatment, they preferred to wait and suffer because of a fear of painful dental treatments and a reluctance to undertake certain procedures. Persons receiving public assistance have perceptions about dental health and illness that prevent them from receiving early treatment for tooth decay, which may lead to disagreements with dentists when planning dental treatments.

  8. Effects of hearing and vision impairments on the Montreal Cognitive Assessment.

    Science.gov (United States)

    Dupuis, Kate; Pichora-Fuller, M Kathleen; Chasteen, Alison L; Marchuk, Veronica; Singh, Gurjit; Smith, Sherri L

    2015-01-01

    Many standardized measures of cognition include items that must be seen or heard. Nevertheless, it is not uncommon to overlook the possible effects of sensory impairment(s) on test scores. In the current study, we investigated whether sensory impairments could affect performance on a widely used screening tool, the Montreal Cognitive Assessment (MoCA). Three hundred and one older adults (mean age = 71 years) completed the MoCA and also hearing and vision tests. Half of the participants had normal hearing and vision, 38% impaired hearing, 5% impaired vision, and 7% had dual-sensory impairment. More participants with normal sensory acuity passed the MoCA compared to those with sensory loss, even after modifying scores to adjust for sensory factors. The results suggest that cognitive abilities may be underestimated if sensory problems are not considered and that people with sensory loss are at greater risk of cognitive decline.

  9. Montreal Communication Evaluation Battery--Portuguese version: age and education effects.

    Science.gov (United States)

    Kerr, Mônica de Souza; Pagliarin, Karina Carlesso; Mineiro, Ana; Ferré, Perrine; Joanette, Yves; Fonseca, Rochele Paz

    2015-01-01

    To verify age and education effects on communication performance of healthy adults in the Montreal Communication Evaluation Battery, Portuguese version (MAC-PT). The sample comprised 90 healthy adults from Portugal, European Portuguese speakers, divided into nine groups according to educational level (4-9, 10-13, and > 13 years of formal schooling) and age (19-40, 41-64, and 65-80 years). The influence of age and education was assessed by comparing mean scores between groups, using a two-way analysis of variance followed by Bonferroni post hoc tests (p ≤ 0.05). The results showed that participants' performance was influenced by age in pragmatic-inferential, discursive, and prosodic tasks. Education had the greatest influence on the performance in all processes evaluated by the MAC-PT. Age and education seem to influence the communicative performance and should be considered in the assessment of neurological patients.

  10. Designing for "the little convalescents": children's hospitals in Toronto and Montreal, 1875-2006.

    Science.gov (United States)

    Adams, Annmarie; Theodore, David

    2002-01-01

    This paper explores more than a century of changing ideas about the health of Canadian children through the architecture of pediatric hospitals in Montreal and Toronto. As a unique source in the history of medicine, hospital architecture reveals three distinct phases in the construction of children as patients. Early 20th-century children's hospitals remained bastions of older spatial attitudes towards health. The postwar hospital was self-consciously modern, with an arrangement more scientific and institutional than its predecessor. Through reference to other typologies, the postmodern hospital marks a curious return to the earlier attitude that children's health is a family affair. Is the hospital a home for children or an institution for science?

  11. Organizational Strategies for Critical Transportation Infrastructure: Characteristics of Urban Resilience. The Case of Montreal.

    Science.gov (United States)

    Beauregard, Stéphane; Therrien, Marie-Christine; Normandin, Julie-Maude

    2010-05-01

    Organizational Strategies for Critical Transportation Infrastructure: Characteristics of Urban Resilience. The Case of Montreal. Stéphane Beauregard M.Sc. Candidate École nationale d'administration publique Julie-Maude Normandin Ph.D. Candidate École nationale d'administration publique Marie-Christine Therrien Professor École nationale d'administration publique The proposed paper presents preliminary results on the resilience of organizations managing critical infrastructure in the Metropolitan Montreal area (Canada). A resilient city is characterized by a network of infrastructures and individuals capable of maintaining their activities in spite of a disturbance (Godschalk, 2002). Critical infrastructures provide essential services for the functioning of society. In a crisis situation, the interruption or a decrease in performance of critical infrastructures could have important impacts on the population. They are also vulnerable to accidents and cascading effects because on their complexity and tight interdependence (Perrow, 1984). For these reasons, protection and security of the essential assets and networks are one of the objectives of organizations and governments. But prevention and recovery are two endpoints of a continuum which include also intermediate concerns: ensuring organizational robustness or failing with elegance rather than catastrophically. This continuum also includes organizational resilience (or system), or the ability to recover quickly after an interruption has occurred. Wildavsky (1988) proposes that anticipation strategies work better against known problems while resilience strategies focus on unknown problems. Anticipation policies can unnecessarily immobilize investments against risks, while resilience strategies include the potential for a certain sacrifice in the interests of a more long-term survival and adaptation to changing threats. In addition, a too large confidence in anticipation strategies can bring loss of capacity of an

  12. Musical cognition in Alzheimer's disease: application of the Montreal Battery of Evaluation of Amusia.

    Science.gov (United States)

    Campanelli, Alessandra; Rendace, Lidia; Parisi, Francesco; D'Antonio, Fabrizia; Imbriano, Letizia; de Lena, Carlo; Trebbastoni, Alessandro

    2016-07-01

    The aim of this study was to assess certain musical abilities in 30 patients with Alzheimer's disease (AD) and 30 healthy controls by using the complete version of the Montreal Battery of Evaluation of Amusia (MBEA). This battery evaluates melodic (scale, contour, and interval) and temporal (rhythm and meter) perception of music and musical memory. We found that altered musical processing is a common feature in AD. Despite that, AD subjects show partially spared abilities for temporal organization of music, though not for melodic perception and musical memory. This peculiar dysfunctional pattern could depend on the neurodegenerative involvement of some specific areas for music perception and memory in the brains of AD patients. Further studies are needed to investigate the usefulness of additional musical tests like the MBEA on larger samples to confirm our preliminary data. © 2016 New York Academy of Sciences.

  13. Occupation, Exclusion and the “Homeless Problem” during Occupy Montreal

    Directory of Open Access Journals (Sweden)

    Véronique Fortin

    2015-03-01

    Full Text Available As part of the Occupy movement in the fall of 2011, the Indignés in Montreal occupied a public square and set up an autonomous encampment to protest against socio-economic inequality. However, cohabitation problems soon arose in the camp and tensions between so-called homeless occupiers and Indignés occupiers developed, leading to the exclusion of the homeless people. This paper addresses this tension and inscribes the concept of occupation in a larger historical context. It teases out the legal histories of occupation-as-exclusive-appropriation to cast another light on occupation-as-protest. Como parte del movimiento “Ocupa” del otoño de 2011, los indignados de Montreal ocuparon una plaza pública, y levantaron un campamento autónomo para protestar por la desigualdad socio-económica. Sin embargo, en el campamento pronto se dieron problemas de cohabitación, y se produjeron tensiones entre los llamados ocupantes sin-techo y los ocupantes indignados, que llevaron a la exclusión de los primeros. Este artículo refleja esta tensión, y sitúa el concepto de ocupación en un contexto histórico mayor. Clarifica la historia legal de “ocupación como apropiación exclusiva” para dar una luz diferente a la “ocupación como protesta”. DOWNLOAD THIS PAPER FROM SSRN: http://ssrn.com/abstract=2569088

  14. Control and monitoring of landfill gas underground migration at the City of Montreal sanitary landfill site

    International Nuclear Information System (INIS)

    Heroux, M.; Turcotte, L.

    1997-01-01

    The proposed paper covers the various aspects of control and monitoring of potential landfill gas (LFG) migration through soil voids or rock fractures at the City of Montreal sanitary landfill site. It depicts the social, geographical and geological context and presents a brief history of the landfill site. It describes the LFG collecting system and LFG migration monitoring equipment and programs. Finally it presents monitoring data taken over last few years. The landfill site is located in a well populated urban area. Since 1968, about 33 million metric tons of domestic and commercial waste have been buried in a former limestone quarry. Because of houses and buildings in the vicinity, 100 m in some locations, LFG underground migration is a major risk. LFG could indeed infiltrate buildings and reach explosive concentrations. So it must be controlled. The City of Montreal acquired the site in 1988 and has progressively built a LFG collecting system, composed of more than 288 vertical wells, to pump out of the landfill 280 million m 3 of gas annually. To verify the efficiency of this system to minimize LFG underground migration, monitoring equipment and programs have also been designed and put into operation. The monitoring network, located all around the landfill area, is composed of 21 well nests automated to monitor presence of gas in the ground in real time. In addition, 55 individual wells, where manual measurements are made, are also available. To complete the monitoring program, some measurements are also taken in buildings, houses and underground utilities in the neighborhood of the site. Monitoring data show that LFG underground migration is well controlled. They also indicate significant decrease of migration over the years corresponding to improvements to the LFG collecting system

  15. Soundscape studies in Montreal's Biodome: using enclosed ecosystems to explain biodiversity to the public

    Science.gov (United States)

    Fisher Favret, K. E.

    2016-02-01

    The Biodome in Montreal is a unique public museum with over 750 species organized into five different ecosystems. We spent several weeks obtaining soundscapes from three of these: Gulf of St. Lawrence, Labrador Coast, and Sub-Antarctic Islands. The idea was to leverage the accessibility and known biodiversity of these mesocosms to calibrate instruments, evaluate methods for assessing biodiversity, and educate people ranging from the penguin keeper to the general public about soundscape ecology and biodiversity assessments. The Gulf of St. Lawrence exhibit has hundreds of fish that belong to 20 species swimming in 2.5 million gallons of seawater, with seabirds and invertebrates nearby. The Sub-Antarctic Islands exhibit, by contrast, has four species of penguins. As part of Montreal's Space for Life program, there is a searchable index of the species available to the public: http://espacepourlavie.ca/en/fauna-and-flora-biodome.The emerging field of soundscape ecology offers a new approach for effectively monitoring changes in sounds generated by communities ranging from urban centers to oceans. The entropy-based approach pioneered by Sueur et al., (2008) characterizes acoustic spectrograms based on the spectral space-filling properties of the sound producers. By calculating the complexity of the acoustic environment, we can detect cycles over various time scales. Disturbed systems can be detected by changes in the timing and frequency of sounds filling various "niches" in the soundscape that might act as early warnings of changes induced on scales from single events to climate shifts. These changes range from presence or absence of vocalizations by individual species, to changes in the higher order statistics of the daily sound structures that include sounds with physical, biological, and human origins. Here we show what we have learned so far about comparing enclosed ecosystems to the real world outside, and some of the challenges and rewards of using soundscape

  16. Chapter 2. The production units

    International Nuclear Information System (INIS)

    1998-01-01

    In the second chapter of this CD ROM the production units of the Slovak Electric, Plc. (Slovenske elektrarne, a.s.), are presented. It consist of next paragraphs: (1) Nuclear power plants (A-1 Nuclear Power Plant (History, Technological scheme, basic data are presented); V-1, V-2 Bohunice Nuclear Power Plant (History 1972-1985, technological scheme; nuclear safety, radiation protection, heat supply, international co-operation and basic data are presented); Mochovce Nuclear Power Plant (History 1980-1998, technological scheme, construction completion, milestones of commissioning, safety and environmental protection as well as basic data are included). (2) Conventional sources of energy (Vojany fossil power plant (History 1959-1992, Technological units of power plant, Impact of operation on the environment, Plant of Vojany FPP Renewal and Reconstruction, Basic data are listed), Novaky fossil power plant (History 1949-1998, Technological scheme, current investment construction, basic data, Handlova heating plant). Kosice Combined Heat Power Plant (History 1960-1995, technological scheme, State metrology centre, acredited chemical laboratory, basic data). (3) Hydroelectric power plants (Trencin HPPs: Cierny Vah pumped storage HPP, Liptovska Mara HPP, Orava HPP, Sucany HPP, Miksova HPP, Nosice HPP, Velke Kozmalovce HPP, Gabcikovo HPP, Dubnica HPP, Nove Mesto n/V HPP, Madunice HPP, Kralova HPP) and Dobsina HPPs: (Dobsina HPP, Ruzin HPP, Domasa HPP, small HPPs) are presented

  17. Chapter 12: Human microbiome analysis.

    Directory of Open Access Journals (Sweden)

    Xochitl C Morgan

    Full Text Available Humans are essentially sterile during gestation, but during and after birth, every body surface, including the skin, mouth, and gut, becomes host to an enormous variety of microbes, bacterial, archaeal, fungal, and viral. Under normal circumstances, these microbes help us to digest our food and to maintain our immune systems, but dysfunction of the human microbiota has been linked to conditions ranging from inflammatory bowel disease to antibiotic-resistant infections. Modern high-throughput sequencing and bioinformatic tools provide a powerful means of understanding the contribution of the human microbiome to health and its potential as a target for therapeutic interventions. This chapter will first discuss the historical origins of microbiome studies and methods for determining the ecological diversity of a microbial community. Next, it will introduce shotgun sequencing technologies such as metagenomics and metatranscriptomics, the computational challenges and methods associated with these data, and how they enable microbiome analysis. Finally, it will conclude with examples of the functional genomics of the human microbiome and its influences upon health and disease.

  18. Various chapter styles for the memoir class

    DEFF Research Database (Denmark)

    Madsen, Lars

    2012-01-01

    Document showcasing various chapter title page designs either included in the LaTeX memoir class or is easily manually coded.......Document showcasing various chapter title page designs either included in the LaTeX memoir class or is easily manually coded....

  19. Chapter 6. Landscape Analysis for Habitat Monitoring

    Science.gov (United States)

    Samuel A. Cushman; Kevin McGarigal; Kevin S. McKelvey; Christina D. Vojta; Claudia M. Regan

    2013-01-01

    The primary objective of this chapter is to describe standardized methods for measur¬ing and monitoring attributes of landscape pattern in support of habitat monitoring. This chapter describes the process of monitoring categorical landscape maps in which either selected habitat attributes or different classes of habitat quality are represented as different patch types...

  20. Chapter 1: Standard application in photon dosimetry

    Energy Technology Data Exchange (ETDEWEB)

    Peixoto, Jose Guilherme Pereira; Potiens, Maria da Penha

    2014-07-01

    Chapter 1 presents: The proprieties; Absolute dosimeter; Traceable dosimeter; Secondary standard dosimeters and their characterization: ionization chamber properties and Ionization chambers (shape and volume); Calibration method: substitute method, tip-to-tip method and known radiation field or Dosimetry method and Calibration results related to chapter 1 are presented.

  1. Chapter 17: Estimating Net Savings: Common Practices

    Energy Technology Data Exchange (ETDEWEB)

    Violette, D. M.; Rathbun, P.

    2014-09-01

    This chapter focuses on the methods used to estimate net energy savings in evaluation, measurement, and verification (EM&V) studies for energy efficiency (EE) programs. The chapter provides a definition of net savings, which remains an unsettled topic both within the EE evaluation community and across the broader public policy evaluation community, particularly in the context of attribution of savings to particular program. The chapter differs from the measure-specific Uniform Methods Project (UMP) chapters in both its approach and work product. Unlike other UMP resources that provide recommended protocols for determining gross energy savings, this chapter describes and compares the current industry practices for determining net energy savings, but does not prescribe particular methods.

  2. IL-17A acts via p38 MAPK to increase stability of TNF-alpha-induced IL-8 mRNA in human ASM.

    Science.gov (United States)

    Henness, Sheridan; van Thoor, Eveline; Ge, Qi; Armour, Carol L; Hughes, J Margaret; Ammit, Alaina J

    2006-06-01

    Human airway smooth muscle (ASM) plays an immunomodulatory role in asthma. Recently, IL-17A has become of increasing interest in asthma, being found at elevated levels in asthmatic airways and emerging as playing an important role in airway neutrophilia. IL-17A predominantly exerts its neutrophil orchestrating role indirectly via the induction of cytokines by resident airway structural cells. Here, we perform an in vitro study to show that although IL-17A did not induce secretion of the CXC chemokine IL-8 from ASM cells, IL-17A significantly potentiates TNF-alpha-induced IL-8 protein secretion and gene expression in a concentration- and time-dependent manner (P ASM cells, acting via a p38 MAPK-dependent posttranscriptional pathway to augment TNF-alpha-induced secretion of the potent neutrophil chemoattractant IL-8 from ASM cells.

  3. Chapter 1: Biomedical knowledge integration.

    Directory of Open Access Journals (Sweden)

    Philip R O Payne

    Full Text Available The modern biomedical research and healthcare delivery domains have seen an unparalleled increase in the rate of innovation and novel technologies over the past several decades. Catalyzed by paradigm-shifting public and private programs focusing upon the formation and delivery of genomic and personalized medicine, the need for high-throughput and integrative approaches to the collection, management, and analysis of heterogeneous data sets has become imperative. This need is particularly pressing in the translational bioinformatics domain, where many fundamental research questions require the integration of large scale, multi-dimensional clinical phenotype and bio-molecular data sets. Modern biomedical informatics theory and practice has demonstrated the distinct benefits associated with the use of knowledge-based systems in such contexts. A knowledge-based system can be defined as an intelligent agent that employs a computationally tractable knowledge base or repository in order to reason upon data in a targeted domain and reproduce expert performance relative to such reasoning operations. The ultimate goal of the design and use of such agents is to increase the reproducibility, scalability, and accessibility of complex reasoning tasks. Examples of the application of knowledge-based systems in biomedicine span a broad spectrum, from the execution of clinical decision support, to epidemiologic surveillance of public data sets for the purposes of detecting emerging infectious diseases, to the discovery of novel hypotheses in large-scale research data sets. In this chapter, we will review the basic theoretical frameworks that define core knowledge types and reasoning operations with particular emphasis on the applicability of such conceptual models within the biomedical domain, and then go on to introduce a number of prototypical data integration requirements and patterns relevant to the conduct of translational bioinformatics that can be addressed

  4. Activated sludge model (ASM) based modelling of membrane bioreactor (MBR) processes: a critical review with special regard to MBR specificities.

    Science.gov (United States)

    Fenu, A; Guglielmi, G; Jimenez, J; Spèrandio, M; Saroj, D; Lesjean, B; Brepols, C; Thoeye, C; Nopens, I

    2010-08-01

    Membrane bioreactors (MBRs) have been increasingly employed for municipal and industrial wastewater treatment in the last decade. The efforts for modelling of such wastewater treatment systems have always targeted either the biological processes (treatment quality target) as well as the various aspects of engineering (cost effective design and operation). The development of Activated Sludge Models (ASM) was an important evolution in the modelling of Conventional Activated Sludge (CAS) processes and their use is now very well established. However, although they were initially developed to describe CAS processes, they have simply been transferred and applied to MBR processes. Recent studies on MBR biological processes have reported several crucial specificities: medium to very high sludge retention times, high mixed liquor concentration, accumulation of soluble microbial products (SMP) rejected by the membrane filtration step, and high aeration rates for scouring purposes. These aspects raise the question as to what extent the ASM framework is applicable to MBR processes. Several studies highlighting some of the aforementioned issues are scattered through the literature. Hence, through a concise and structured overview of the past developments and current state-of-the-art in biological modelling of MBR, this review explores ASM-based modelling applied to MBR processes. The work aims to synthesize previous studies and differentiates between unmodified and modified applications of ASM to MBR. Particular emphasis is placed on influent fractionation, biokinetics, and soluble microbial products (SMPs)/exo-polymeric substances (EPS) modelling, and suggestions are put forward as to good modelling practice with regard to MBR modelling both for end-users and academia. A last section highlights shortcomings and future needs for improved biological modelling of MBR processes. (c) 2010 Elsevier Ltd. All rights reserved.

  5. Flujo espiratorio máximo en niños asmáticos: Casos y controles

    Directory of Open Access Journals (Sweden)

    Arturo Recabarren Lozada

    1995-04-01

    Full Text Available Con el fin de determinar las variaciones del Flujo Espiratorio Máximo (PEF, se estudiaron a 38 niños asmáticos (CASOS en período intercrítico de la enfermedad y a 38 niños sanos (CONTROLES, de ambos sexos comprendidos entre los 5 y 15 años de edad. Los niños asmáticos fueron clasificados por parámetros clínicos en determinado grado de severidad de asma bronquial, determinando el PEF de cada niño objeto de estudio conel mini-Wright Peak Flow Meter, en 2 registros diarios a los 06 y 18 horas, durante 7 días consecutivos, obteniendo la variabilidad del mismo. Se encuentra diferencia en la variabilidad global de niños asmáticos de todos los grados de severidad de la enfermedad comprada con la de los niños normales, con diferencia estadística altamente significativa (p<0.000001. Las variaciones diurnas del PEF ayuda en el diagnóstico del asma bronquial y también son útiles para realizar la catalogación de severidad de la enfermedad. El PEF correlaciona bien con los síntomas presentados por los pacientes y por lo tanto guarda correspondencia con la Hiperreactividad bronquial (HRB del niño asmático. Postulamos que un niño con historia clínica sugestiva, una variabilidad global mayor del 8% indica que el diagnóstico de asma es altamente probable (Rev Med Hered 1995; 6: 76-82

  6. ASME B89.4.19 Performance Evaluation Tests and Geometric Misalignments in Laser Trackers

    Directory of Open Access Journals (Sweden)

    Muralikrishnan, Bala

    2009-01-01

    Full Text Available Small and unintended offsets, tilts, and eccentricity of the mechanical and optical components in laser trackers introduce systematic errors in the measured spherical coordinates (angles and range readings and possibly in the calculated lengths of reference artifacts. It is desirable that the tests described in the ASME B89.4.19 Standard [1] be sensitive to these geometric misalignments so that any resulting systematic errors are identified during performance evaluation. In this paper, we present some analysis, using error models and numerical simulation, of the sensitivity of the length measurement system tests and two-face system tests in the B89.4.19 Standard to misalignments in laser trackers. We highlight key attributes of the testing strategy adopted in the Standard and propose new length measurement system tests that demonstrate improved sensitivity to some misalignments. Experimental results with a tracker that is not properly error corrected for the effects of the misalignments validate claims regarding the proposed new length tests.

  7. Interim status report on the revision of ASME PTC 12.1 -- closed feedwater heaters

    International Nuclear Information System (INIS)

    Stellern, J.L.; Hoobler, J.V.; Milton, J.W.; Welch, T.; Kona, C.; Thompson, H.N.; Tsou, J.L.

    1993-01-01

    The ASME Performance Test Code (PTC) 12.1-1978 for the performance testing of feedwater heaters is being revised extensively and updated. The committee anticipates that the final draft of the proposed Code will be ready for industry review in 1993. This Code revision will greatly enhance the usefulness and cost effectiveness of feedwater heater performance testing. This paper has been prepared to report on the progress of the committee and to disseminate information on the nature of the revision. Included in this paper are some of the notable changes intended for the Code. The most extensive change is the calculation method, which is described in step-by-step detail. An approach is also described for using ultrasonic flow techniques to test individual or split-string feedwater heaters, when flow nozzles are not available. Additionally some educational information on the use and limitations of ultrasonic measurement instrumentation is included. Discussion is also included on the required uncertainty analysis. 3 refs., 2 figs., 2 tabs

  8. ASM-Triggered Too Observations of Kilohertz Oscillations in Three Atoll Sources

    Science.gov (United States)

    Kaaret, P.; Swank, Jean (Technical Monitor)

    2000-01-01

    Three Rossi Timing Explorer (RXTE) observations were carried out for this proposal based on target of opportunity triggers derived from the All-Sky Monitor (ASM) on RXTE. We obtained short observations of 4U1636-536 (15ks) and 4U1735-44 (23ks) and a longer observation of 4U0614+091 (117ks). Our analysis of our observations of the atoll neutron star x-ray binary 4U1735-44 lead to the discovery of a second high frequency quasiperiodic oscillation (QPO) in this source. These results were published in the Astrophysical Journal Letters. The data obtained on the source 4U0614+091 were used in a comprehensive study of this source, which will be published in the Astrophysical Journal. The data from this proposal were particularly critical for that study as they lead to the detection of the highest QPO frequency every found in the x-ray emission from an x-ray binary which will be important in placing limits on the equation of state of nuclear matter.

  9. 2016 ASMS Workshop Review: Next Generation LC/MS: Critical Insights and Future Perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Gao, Hongying; Makarov, Alexander; Smith, Richard D.

    2017-04-17

    The pilot workshop on BNext Generation LC/MS: Critical Insights and Future Perspectives was held on the evening of June 6, 2016 at the 64th ASMS Conference on Mass Spectrometry and Allied Topics held in San Antonio, TX. The workshop, chaired by Hongying Gao (Pfizer), consisted of stimulating talks from distinguished speakers and open discussion among the audience and invited presenters.The objectives of this workshop were to better understand the advances and limitations of current technologies; to exchange perspectives on the next generation LC/MS; and to discuss/debate the features of next generation LC/MS focusing on the following three questions: (1) What would the next generation LC/MS look like? (2) How would it change the way we do analysis? and (3) What fundamental issues need to be resolved? A real-world case in the biopharmaceutical industry was presented by Hongying Gao on the needs by industry for LC/MS innovation and technology advancements. The primary invited speakers were Alexander Makarov (Thermo Fisher Scientific) and Richard (Dick) Smith (Pacific Northwest National Laboratory). The open discussions started with Q&A and comments for Alexander Makarov and Dick Smith, followed by insights and perspectives from members of the audience and other invited presenters who shared their thoughts addressing the above questions.

  10. Section XI of the ASME code: A new approach to qualifying procedures and personnel

    International Nuclear Information System (INIS)

    Chokie, L.J.

    1985-01-01

    Following the results of numerous programs and trials which measured the effectiveness of the nondestructive examinations required by Section XI of the ASME Code on Nuclear Inservice Inspection of Nuclear Power Plant Components, revisions have been made to the Code to improve the over-all reliability. The results of the round-robin programs designed to measure the reliability of detection and the reliability of correctly sizing the flaws indicated that the rather specific requirements in Section XI did not always achieve the desired results in both heavy section pressure vessel steels, nor in austenitic stainless steel piping welds. One of the two major contributors to the less-than-desired reliability was identified as being the training, understanding and qualification of the personnel; the other was principally due to the fact that the exact methods specified in the Code were not always applicable on every steel or every weld joint configuration. Revisions to the Code were proposed and approved to address these deficiencies, and which revisions have been issued for immediate implementation. The new approach is to permit any procedure or method to be used provided the procedure can be qualified on actual specimens containing the type of flaws to be detected, and following the qualification of the procedure, the personnel must be trained and qualified to obtain a certain level of proficiency using the qualified procedure on actual samples. The qualification of each procedure and each individual is required before examining an actual nuclear plant

  11. The application of RCM to ASME code requirements for in-service testing

    International Nuclear Information System (INIS)

    Rowley, C.W.

    1990-01-01

    This paper reports that the high reliability of nuclear power plant systems and components is highly important for both nuclear safety and electrical power production economics. The optimum operating performance of these plant systems and components is heavily dependent on the original or modified design for its inherent reliability and the appropriate trade-off in preventive and corrective maintenance for its developed reliability. In developing this optimum operating performance goal, the plant staff could rely solely on the experience of its personnel. However using this internal subjective approach, the average nuclear power availability has been far less than 80%. Obviously the production economics of a nuclear power plant is the province of the owner-operator, but the safety system and component performance impacts the entire industry. Hence the nuclear industry needs to have in-service testing requirements that maintain the necessary safety standards. Historically the ASME Inservice Testing Code has been a vehicle for defining some of those necessary safety standards, such as inservice testing of pumps, valves, and snubbers. The nuclear industry needs to expand the code testing to include all the systems that affect these necessary safety standards

  12. Iterative and non-iterative solutions of engine flows using ASM and k-ε turbulence models

    International Nuclear Information System (INIS)

    Khaleghi, H.; Fallah, E.

    2003-01-01

    Various turbulent models are widely developed in order to make a good prediction of turbulence phenomena in different applications. The standard k-ε model shows a poor prediction for some applications. The Reynolds Stress Model (RSM) is expected to give a better prediction of turbulent characteristics, because a separate differential equation for each Reynolds stress component is solved in this model. In order to save both time and memory in this calculation a new Algebraic Stress Model (ASM) which was developed by Lumly et al in 1995 is used for calculations of flow characteristics in the internal combustion engine chamber. With using turbulent realizability principles, this model becomes a powerful and reliable turbulence model. In this paper the abilities of the model is examined in internal combustion engine flows. The results of ASM and k-ε models are compared with the experimental data. It is shown that the poor predictions of k-ε model are modified by ASM model. Also in this paper non-iterative PISO and iterative SIMPLE solution algorithms are compared. The results show that the PISO solution algorithm is the preferred and more efficient procedure in the calculation of internal combustion engine. (author)

  13. Elastic-plastic stress analysis and ASME code evaluation of a bottomhead penetration in a reactor pressure vessel

    International Nuclear Information System (INIS)

    Ranganath, S.

    1979-01-01

    Nuclear pressure vessel components are designed to meet the requirements of Section III of the ASME Boiler and Pressure Vessel Code. Specifically, the design must satisfy the limits on stress range and fatigue usage prescribed in NB-3200, Section III ASME Code for the various design and operating conditions for the component. The Code requirements assure that the component does not experience gross yielding and that in general, elastic shakedown occurs following cyclic loading. When elastic stress analysis is performed this can be shown by meeting the limits in the Code on Primary and Primary plus Secondary (P+Q) stress intensities. However, when the P+Q limits cannot be met and elastic Shakedown cannot be demonstrated, plastic analysis may be performed to meet the requirements of the Code. This paper describes the elastic-plastic stress analysis of a Boiling Water Reactor Vessel bottom head in-core penetration and illustrates how plastic analysis can be used in ASME Code evaluations to show Code compliance. Details of the thermal analysis, elastic-plastic stress analysis and fatigue evaluation are presented and it is shown that the in-core penetration satisfies the code requirements. 6 refs

  14. Statistical re-evaluation of the ASME K{sub IC} and K{sub IR} fracture toughness reference curves

    Energy Technology Data Exchange (ETDEWEB)

    Wallin, K.; Rintamaa, R. [Valtion Teknillinen Tutkimuskeskus, Espoo (Finland)

    1998-11-01

    Historically the ASME reference curves have been treated as representing absolute deterministic lower bound curves of fracture toughness. In reality, this is not the case. They represent only deterministic lower bound curves to a specific set of data, which represent a certain probability range. A recently developed statistical lower bound estimation method called the `Master curve`, has been proposed as a candidate for a new lower bound reference curve concept. From a regulatory point of view, the Master curve is somewhat problematic in that it does not claim to be an absolute deterministic lower bound, but corresponds to a specific theoretical failure probability that can be chosen freely based on application. In order to be able to substitute the old ASME reference curves with lower bound curves based on the master curve concept, the inherent statistical nature (and confidence level) of the ASME reference curves must be revealed. In order to estimate the true inherent level of safety, represented by the reference curves, the original data base was re-evaluated with statistical methods and compared to an analysis based on the master curve concept. The analysis reveals that the 5% lower bound Master curve has the same inherent degree of safety as originally intended for the K{sub IC}-reference curve. Similarly, the 1% lower bound Master curve corresponds to the K{sub IR}-reference curve. (orig.)

  15. Development and application of proposed ASME Section XI Code changes for risk-based inspection of piping

    International Nuclear Information System (INIS)

    West, R.A.

    1996-01-01

    This synopsis has been written to describe a perspective on the development and application of ASME Section XI Code changes for risk-based inspection of piping. The content is specifically related to the use of risk-based technology for Inservice Inspection (ISI) of piping and efforts made to support the ASME Research/Westinghouse Owners Group/Millstone Unit 3 approach for use of this technology. The opinions contained herein may or may not reflect those of the ASME Codes and Standards Committees responsible for these activities. In order to take such a detailed technical subject and put it into an understandable format, the author has chosen to provide an analogy to simplify what is actually taking place. Risk-based technology in the ISI of piping can be likened to the process of making and using specifically ground prescription glasses to allow for better vision. It provides a process to develop and use these uniquely ground glasses that will dynamically focus on all the locations and obstacles within a plant's piping systems that could cause that plant to trip and fall; more importantly it identifies the locations where the fall could possibly hurt someone else. In this way, Nuclear Safety is being addressed

  16. Modeling a bench-scale alternating aerobic/anoxic activated sludge system for nitrogen removal using a modified ASM1.

    Science.gov (United States)

    Kim, Hyunook; Noh, Soohong; Colosimo, Mark

    2009-07-01

    The Activated Sludge Model No. 1 (ASM1), developed by The International Association of Water Pollution Research and Control, was applied to model dynamics of NH4+, and NO3- in a bench scale alternating aerobic-anoxic (AAA) activated sludge system for nitrogen removal. The model was modified by eliminating inert soluble COD (S(I)) and inert particulate COD (X(I)) from the model's state variables as these two variables are not involved in any biological reaction and are not readily measurable with conventional routine COD analysis. It was assumed that the soluble COD and particulate COD of wastewater represent readily biodegradable COD (S(S)) and slowly biodegradable (X(S)) in the model, respectively. In addition, alkalinity was also removed from the model, since alkalinity of an AAA system remains stable due to the cyclic modes of the system. Even with the elimination of the three state variables and the assumption made, the model could reasonably predict the NH4+ and NO3- dynamics of the AAA system, and effluent NH4+ and NO3- concentrations with adjustment of only a few kinetic parameters. Compared to the original ASM1, it is expected that the modified ASM1 presented in this study can be more easily utilized by engineers in designing or operating an AAA system in practice, since it requires simple characterization of wastewater COD.

  17. Comparative study of design of piping supports class 1, 2 and 3 considering german code KTA and ASME III - NF

    International Nuclear Information System (INIS)

    Faloppa, Altair A.; Fainer, Gerson; Mattar Neto, Miguel; Elias, Marcos V.

    2013-01-01

    The objective of this paper is developing a comparative study of the design criteria for class 1, 2, 3 piping supports considering the American Code ASME Section III - NF and the German Code KTA 3205.1 to the Primary Circuit, KTA 3205.2 to the others systems and KTA 3205.3 series-production standards supports of a PWR nuclear power plant. An additional purpose of the paper is a general analysis of the main design concepts of the American Code ASME Boiler and Pressure Vessel Code, Section III, Division 1 and German Nuclear Design Code KTA that was performed in order to aid the comparative study proposed. The relevance of this study is to show the differences between codes ASME and KTA since they were applied in the design of the Nuclear Power Plants Angra 1 and Angra 2, and to the design of Angra 3, which is at the moment under construction. It is also considered their use in the design of nuclear installations such as RMB - Reator MultiProposito Brasileiro and LABGENE - Laboratorio de Geracao Nucleoeletrica. (author)

  18. Función adrenal y metabolismo lipídico en niños asmáticos tratados con budesonida

    Directory of Open Access Journals (Sweden)

    Paoli-de Valeri Mariela

    1999-01-01

    Full Text Available Objetivo. Evaluar el efecto de bajas dosis de budesonida inhalado sobre la función adrenal y el metabolismo lipídico en niños asmáticos. Material y métodos. Se estudiaron: 10 niños asmáticos (edad promedio, 8.6 años tratados con budesonida inhalado (200-300 µg/día por un lapso mayor a tres meses (grupo A; 15 niños asmáticos (edad promedio, 7.8 años sin tratamiento esteroideo (grupo B, y 10 niños no asmáticos (grupo C. Se determinaron los niveles de cortisol basal y postestímulo con ACTH, andrógenos adrenales, lípidos y cortisol urinario. Resultados. Entre los grupos A y B no hubo diferencias significativas en las variables estudiadas. En los niños asmáticos (grupo A-B el cortisol urinario fue significativamente mayor en relación con el grupo C. Los niveles de triglicéridos, colesterol total, colesterol de la lipoproteína de baja densidad e índices aterogénicos fueron mayores en el grupo de niños asmáticos, con y sin budesonida, comparados con el grupo C. Conclusiones. El tratamiento con dosis bajas de budesonida inhalado en niños asmáticos no modificó la función del eje adrenal ni el metabolismo lipídico. Los pacientes asmáticos presentaron un perfil lipídico aterogénico que podría incrementar el riesgo de enfermedad cardiovascular.

  19. The new topical ascomycin derivative SDZ ASM 981 does not induce skin atrophy when applied to normal skin for 4 weeks: a randomized, double-blind controlled study.

    Science.gov (United States)

    Queille-Roussel, C; Paul, C; Duteil, L; Lefebvre, M C; Rapatz, G; Zagula, M; Ortonne, J P

    2001-03-01

    SDZ ASM 981 is a selective inhibitor of inflammatory cytokines released from T lymphocytes and mast cells, which has been developed for the treatment of inflammatory skin diseases. In the present study, the atrophogenic potential of SDZ ASM 981 1% cream in humans was compared with that of medium and highly potent topical steroids, and vehicle. Four different preparations, SDZ ASM 981 1% cream, the corresponding vehicle of SDZ ASM 981 1% cream, betamethasone-17-valerate 0.1% cream and triamcinolone acetonide 0.1% cream, were applied to the volar aspect of the forearms of 16 healthy volunteers, twice daily, 6 days a week, for 4 weeks. Skin thickness was evaluated by ultrasound examination, clinical signs of atrophy by stereomicroscopy, and epidermal thickness was assessed by histology. Both topical corticosteroids induced a significant reduction in skin thickness, as compared with SDZ ASM 981 1% cream and vehicle, which were shown to be equivalent. The difference in skin thickness (measured by ultrasound examination) between patients treated with SDZ ASM 981 1% cream and those receiving either of the two topical steroids was significant from day 8 onwards. Histological analysis performed at day 29 showed significant epidermal thinning with topical steroids compared with SDZ ASM 981 1% cream or the vehicle. Conclusion The lack of atrophogenic properties of SDZ ASM 981 1% cream in this short-term study demonstrates its potential as long-term treatment for inflammatory skin diseases, thus overcoming a major drawback of topical steroids. This may also be important for the treatment of children, and sensitive areas of skin, such as the face and skin-folds.

  20. Function of site. Chapter 2

    International Nuclear Information System (INIS)

    1999-01-01

    In Semipalatinsk test site's history there are two stages for nuclear tests. In first stage (1949-1962) when the nuclear tests have being conducted in atmosphere, and second one (1963-1989) when underground nuclear explosions have being carried out. There were 456 nuclear tests, from which 117 were both the surface and the atmospheric explosions and other underground ones. In the chapter general characteristics of atmospheric nuclear tests, conducted on Semipalatinsk test site in 1949-1962 (chronology of conducting, release energy and kinds of nuclear explosions) are presented in tabular form. Most powerful of explosion was test of hydro- nuclear (hydrogen) bomb - prototype of thermonuclear charge in 1955 with capacity 1.6 Mt. In 1990-1992 the target-oriented radioecological investigation of territory around Semipalatinsk test site was carried out. Specialists dividing all atmospheric explosions by rate local traces, forming out of test site into 4 groups: with very strong contamination, with strong contamination, with weak contamination, and with very weak contamination. To nuclear explosions with very strong contamination were attributed the four explosions carrying out in 29.08.1949, 24.09.1951, 12.08.1953, 24.08.1956. Estimations of radiological situation including external doses of radiation and environment contamination and content of radioactive substances in human body was given by 10 European experts in collaboration with Kazakstan scientists. Results of investigation show that during past period surface contamination, called by nuclear weapons' fissile products was subjected to considerable decay. External doses completely coincidence with natural background. Remains of long living radionuclides are insignificant as well, and in 1995 its approximately were equal to annual exposition doses. One of most damaged settlements is Chagan. On it territory 530 radioactive sources with doses capacity from 100 up to 400 μR/h. Scientists of Semipalatinsk defined

  1. The Montreal Affective Voices: a validated set of nonverbal affect bursts for research on auditory affective processing.

    Science.gov (United States)

    Belin, Pascal; Fillion-Bilodeau, Sarah; Gosselin, Frédéric

    2008-05-01

    The Montreal Affective Voices consist of 90 nonverbal affect bursts corresponding to the emotions of anger, disgust, fear, pain, sadness, surprise, happiness, and pleasure (plus a neutral expression), recorded by 10 different actors (5 of them male and 5 female). Ratings of valence, arousal, and intensity for eight emotions were collected for each vocalization from 30 participants. Analyses revealed high recognition accuracies for most of the emotional categories (mean of 68%). They also revealed significant effects of both the actors' and the participants' gender: The highest hit rates (75%) were obtained for female participants rating female vocalizations, and the lowest hit rates (60%) for male participants rating male vocalizations. Interestingly, the mixed situations--that is, male participants rating female vocalizations or female participants rating male vocalizations--yielded similar, intermediate ratings. The Montreal Affective Voices are available for download at vnl.psy.gla.ac.uk/ (Resources section).

  2. Trade restrictions as a means of enforcing compliance with international environmental law. Montreal Protocol on Substances that Deplete the Ozone Layer

    International Nuclear Information System (INIS)

    Lang, W.

    1996-01-01

    The contribution reviews primarily Art. 4 of the Montreal Protocol and its efficiency for enforcing compliance with obligations under international environmental law and discusses aspects of possible conflicts with GATT law. (CB)

  3. The Geography of Clusters: The Case of the Video Games Clusters in Montreal and in Los Angeles

    OpenAIRE

    Sylvianne Pilon; Diane-Gabrielle Tremblay

    2013-01-01

    The aim of our research was to examine how clusters appear and develop in the video game sector. We thus did a comparative study of the video games cluster in Montreal and Los Angeles. This paper shows that concentration of human creativity in arts and in technology is a significant economic localization factor, but cross-fertilization of sectors and public policy also contributes to the understanding of the emergence of clusters in certain urban regions. Thus, political and industrial facto...

  4. Perceptions, Preferences, and Behavior Regarding Energy and Environmental Costs: The Case of Montreal Transport Users

    Directory of Open Access Journals (Sweden)

    Nayer Daher

    2018-02-01

    Full Text Available Providing travel-related fuel and environmental information to transport users is becoming increasingly relevant. However, the impact of providing such information on users’ travel behavior is yet to be determined. This research examined the perceptions and preferences related to the fuel consumption costs, greenhouse gas (GHG social costs, and health-related air pollution costs, and the influence such information could have on travel behavior. Examining the case of Montreal transport users, the authors conducted a survey in which the respondents were asked general and stated preference questions. The respondents were found to be unaware of the energy and environmental footprints of their travel. Approximately 85% of the respondents were not able to estimate GHG social costs and health-related air pollution costs across different modes. The respondents generally overestimated these costs and they interestingly reported higher environmental costs for public transport (metro compared to cars. They also preferred to receive such information in monetary units, and they were more comfortable in receiving the information through mobile applications over other tools/means. The research also found that fuel and environmental information influence respondents’ travel decisions especially their route choices. Finally, the respondents would be willing to pay an average of 7 Canadian dollars/month in exchange for obtaining the information.

  5. [Community organizations and fighting STDs, HIV and AIDS in Montreal: lessons for sub-Saharan Africa].

    Science.gov (United States)

    Agonnoude, Maurice T; Mesenge, C

    2010-01-01

    The HIV/AIDS pandemic is one of the most important public health problems in the world. In Benin as elsewhere in Africa, the combination of some sociological and sociocultural factors with socio-economic realities have led this pandemic to progress faster in some farming regions than in urban areas. This survey was performed during a three-month internship researching community-based organizations in Montreal that care for HIV/AIDS patients. to analyse the actions taken by community-based organisations to combat this pandemic and point out the strengths and weaknesses of this system; - to draw useful lessons to apply in Africa. more than one hundred organisations play a direct or indirect role in the combat against HIV/AIDS in the city ofMontreal. The choice of organisations to visit was determined by their interest for HIV/AIDS prevention and treatment or for the struggle against social exclusion. After a visit and guided tour of the premises of each organisation, one of its officials was interviewed for 20 to 30 minutes (according to a semi-structured outline, appendix 2. The data were analysed manually. the survey showed that even in high-income countries, the same risk behaviors, equally influenced by poverty, social exclusion andvulnerability, lead to this disease. Further, its chronic nature, related to essentially permanent antiretroviral treatments makes it harder for vulnerable groups to maintain healthy behaviours. The concentration of disease in vulnerable groups gives a false sense of security to most of the population, which does not feel concerned, ignores messages intended to raise awareness, and does not participate in voluntary screening. The organisations and actors involved, with the support of public health facilities, battle this vulnerability while providing information and resources to the target groups to help them protect themselves better. This struggle thus remains too focused on these target groups. Efforts must be made to make the

  6. General practitioners' perspective on poverty: a qualitative study in Montreal, Canada.

    Science.gov (United States)

    Loignon, Christine; Gottin, Thomas; Dupéré, Sophie; Bedos, Christophe

    2018-01-16

    Social inequalities in healthcare systems persist worldwide. Physicians' prejudices and negative attitudes towards people living in poverty are one of the determinants of healthcare inequalities. We know very little about general practitioners' (GPs) perceptions of poverty, which shape their attitudes. To identify the perceptions of poverty of GPs who deal with it in everyday practice. A qualitative study based on interviews with GPs working in deprived urban neighbourhoods. In-depth semi-structured interviews were conducted with physicians working in disadvantaged neighbourhoods in Montreal, Canada. Interviews were audio-recorded and transcribed verbatim. Analysis consisted of interview debriefing, transcript coding, and thematic analysis using an inductive and iterative approach. Our study revealed two contrasting perceptions of poverty. The global conception of poverty referred to social determinants and was shared by the majority of physicians interviewed, while the moral conception, centring on individual responsibility, was shared by a minority of participants. The moral judgments and misunderstandings evidenced by GPs regarding poverty suggest avenues for improving general medical training. Understanding social determinants of health should be an important component of this training, to improve access to care for people living in poverty. © The Author 2017. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  7. Montreal Cognitive Assessment (MoCA)-Italian version: regression based norms and equivalent scores.

    Science.gov (United States)

    Conti, Silvia; Bonazzi, Stefano; Laiacona, Marcella; Masina, Marco; Coralli, Mirco Vanelli

    2015-02-01

    The Montreal Cognitive Assessment (MoCA) is a brief cognitive screening instrument developed by Nasreddine et al. to detect mild cognitive impairment, a high-risk condition for Alzheimer's disease and other forms of dementia. In this study we report normative data on the MoCA-Italian version, collected on a sample of 225 Italian healthy subjects ranged in age between 60 and 80 years, and in formal education from 5 to 23 years. The global normal cognition was established in accordance with the Mini-Mental State Examination score and with the Prose Memory Test score (Spinnler and Tognoni, Ital J Neurol Sci 6:25-27, 1987). None of the participants had a history of psychiatric, neurological, cerebrovascular disorders or brain injury or took drugs affecting cognition. Linear regression analysis was performed to evaluate the potential effect of age, education and sex on the MoCA total performance score. We provide correction grids to adjust raw scores and equivalent scores with cut-off value to allow comparison between MoCA performance and others neuropsychological test scores that can be administered on the same subject.

  8. The state of oral and dental health of the homeless and vagrant population of Montreal.

    Science.gov (United States)

    Pizem, P; Massicotte, P; Vincent, J R; Barolet, R Y

    1994-12-01

    Not much is known about the state of oral and dental health of homeless and vagrant people in Montreal. However, a study conducted during April 1993, in conjunction with dental health month, has made it possible to undertake a better evaluation of their oral health status and to identify ways of making dental treatment available to them. Once the oral health status of this population is known, the official body responsible for homeless and vagrant individuals, the "Régie régionale Montréal-Centre," can be given possible solutions for their treatment and care. Most of the homeless are welfare recipients and have access to some basic benefits from this source. One of these benefits is free access to all assured basic dental services. These services are available after a six-month waiting period, and are provided by a dentist of the homeless person's choice. At the beginning of this study, the authors hypothesized that homeless people would prefer to be treated in the hostels and shelters where they sleep, which is currently the situation in Boston. But in 65 per cent of cases, their responses to a questionnaire administered as part of this study were quite different, and indicated that they would prefer to visit a private dentist of their choice. However, there is another important group (35 per cent) who wish to receive dental treatment in the hostels they presently frequent. Any proposed solution should take into consideration both groups of homeless and vagrant persons.

  9. Setting the census household into its urban context: Visualizations from 19th-century Montreal

    Directory of Open Access Journals (Sweden)

    Sherry Olson

    2017-04-01

    Full Text Available Background: Organized by household, North American census data promoted research into household composition, but discouraged research into connections between urban households. Yet these constitute "communications communities" that powerfully influence demographic decisions (Szreter 1996. Objective: How can we uncover relations between urban households? From spatial cues, can we infer social connections that generate constraints on or incentives for the formation of a household, its break-up, reconstitution, or relocation? Methods: For Montreal and its suburbs, 1881‒1901, we employ double geocoding and lot-level precision to explore a dozen types of relationships. Samples for experiment are drawn from a local historical geographic information system (HGIS that integrates tax roll and directory with census data. Results: 'Family' was socially embedded at three levels. Neighbouring of kin was strategic, and kinship was a factor in employment, enterprise, and property development as well as residential choices. In managing property, family networks operated with a horizon of four generations. Conclusions: Introduction of geographic coordinates offers a critical set of neglected cues to relationships between households, such as business partnerships, credit, or use of transit or telephone. In an urban HGIS, advantageous features are lot-level precision and facilities for coding and matching addresses to accommodate alternative levels of spatial aggregation. Contribution: Geocoding is shown to be a breakthrough innovation for exploring urban connectivity. Experiments with maps and networks as tools of visual thinking invite us to rethink the 'census family' at higher levels of relatedness.

  10. Heart Rate Response in Spectators of the Montreal Canadiens Hockey Team.

    Science.gov (United States)

    Khairy, Leia T; Barin, Roxana; Demonière, Fabrice; Villemaire, Christine; Billo, Marie-Josée; Tardif, Jean-Claude; Macle, Laurent; Khairy, Paul

    2017-12-01

    To our knowledge, heart rate responses have not previously been assessed in hockey fans. We quantified heart rate increases in spectators of the Montreal Canadiens, compared televised with live games, explored features associated with peak heart rates, and assessed whether increases correlate with a fan passion score. Healthy adults were enrolled, with half attending live games and half viewing televised games. All subjects completed questionnaires and had continuous Holter monitoring. Intensity of the physical stress response was defined according to previously published heart rate index thresholds as mild ( 1.83). In 20 participants, 35% women, age 46 ± 10 years, the heart rate increased by a median of 92% during the hockey game, from 60 (interquartile range, 54-65) beats per minute at rest to 114 (interquartile range, 103-129) beats per minute (P hockey game is associated with a heart rate response equivalent to vigorous physical stress and a televised game to moderate physical stress. Copyright © 2017 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.

  11. Increased Arctic Deposition of Persistent Compounds as a Result of the Montreal Protocol

    Science.gov (United States)

    Young, C.; Pickard, H. M.; De Silva, A. O.; Spencer, C.; Criscitiello, A. S.; Muir, D.; Sharp, M. J.

    2017-12-01

    Perfluorocarboxylic acids (PFCAs) are among the diverse groups of compounds characterized as persistent organic pollutants. They are toxic, resistant to environmental degradation, and adversely impact human and environmental health. PFCAs with four or fewer carbons, short-chain PFCAs (scPFCAs), are of particular interest because of their increasing levels in the environment, toxicity to plants, and potential for accumulation in some aquatic ecosystems, making them an emerging environmental concern. A minor source of scPFCAs to the Arctic has been shown to be atmospheric transformation of fluoropolymer precursors, followed by deposition. Additional potential sources of scPFCAs to the Arctic are chlorofluorocarbon (CFC)-replacement compounds. Through analysis of an ice core from the Canadian High Arctic, we show that Montreal Protocol-mandated introduction of CFC-replacement compounds for the heat-transfer industry has led to increasing inputs of these scPFCAs to the remote environment. Flux measurements for scPFCAs as a class of contaminants have only been reported in a couple studies to date. Here, we provide the first multi-decadal temporal record of scPFCA deposition, demonstrating a dramatic increase in deposition resulting from emission of CFC-replacements. These results bring to the forefront a need for a holistic approach to environmental risk assessment that considers impacts of replacement substances and degradation products.

  12. Sociology in Global Environmental Governance? Neoliberalism, Protectionism and the Methyl Bromide Controversy in the Montreal Protocol

    Directory of Open Access Journals (Sweden)

    Brian J. Gareau

    2017-10-01

    Full Text Available Sociological studies of global agriculture need to pay close attention to the protectionist aspects of neoliberalism at the global scale of environmental governance. With agri-food studies in the social sciences broadening interrogations of the impact of neoliberalism on agri-food systems and their alternatives, investigating global environmental governance (GEG will help reveal its impacts on the global environment, global science/knowledge, and the potential emergence of ecologically sensible alternatives. It is argued here that as agri-food studies of neoliberalism sharpen the focus on these dimensions the widespread consequences of protectionism of US agri-industry in GEG will become better understood, and the solutions more readily identifiable. This paper illustrates how the delayed phase out of the toxic substance methyl bromide in the Montreal Protocol exemplifies the degree to which the US agri-industry may be protected at the global scale of environmental governance, thus prolonging the transition to ozone-friendly alternatives. Additionally, it is clear that protectionism has had a significant impact on the dissemination and interpretation of science/knowledge of methyl bromide and its alternatives. Revealing the role that protectionism plays more broadly in the agriculture/environmental governance interface, and its oftentimes negative impacts on science and potential alternatives, can shed light on how protectionism can be made to serve ends that are at odds with environmental protection.

  13. SCREENING FOR POSTSTROKE COGNITIVE IMPAIRMENT VIA MINI MENTAL STATE EXAMINATION AND MONTREAL COGNITIVE ASSESSMENT SCALE

    Directory of Open Access Journals (Sweden)

    Mirena Valkova

    2012-10-01

    Full Text Available Objective: The aim of our study is to examine cognitive performance after mild stroke via Mini Mental State Examination (MMSE and Montreal cognitive assessment scale (MoCA and to compare the results.Material and methods: We examined 54 patients with mild stroke (aged 52 to 72 (mean 63.17, SD 5.96; 34 males and 20 females and 54 controls, adjusted by age, sex and education level. All subjects were tested via MMSE (Bulgarian version and MoCa (Bulgarian version. Data was collected in the single step model at the 90th day after stroke incident for patients and at the day of obtaining informed consent for controls. Results: Patients have poorer performance on both MMSE and MoCa than controls. MoCa has comparatively good discriminative validity and sensitivity.Conclusions: Although MMSE is one of the classical screening tools for cognitive impairment widely used in Bulgaria, other screening tools should not be ignored. On the basis of our results, MoCa is also a good screening instrument, especially for poststroke cognitive impairment.

  14. Risk of lung cancer from residential heating and cooking fuels in Montreal, Canada.

    Science.gov (United States)

    Ramanakumar, Agnihotram V; Parent, Marie-Elise; Siemiatycki, Jack

    2007-03-15

    Among the major sources of indoor air pollution are combustion by-products from heating and cooking. Concern is increasing that use of polluting heating and cooking sources can increase cancer risk. In Canada, most cooking and heating currently relies on electricity or natural gas, but, in the past, and still in some areas, coal and wood stoves were used for heating and gas and wood for cooking. In the course of a case-control study of lung cancer carried out in Montreal in 1996-2001, the authors collected information on subjects' lifetime exposure to such sources of domestic pollution by means of a personal interview with the subject or a next-of-kin proxy. Questionnaires were completed for 739 male cases, 925 male controls, 466 female cases, and 616 female controls. Odds ratios were computed in relation to a few indices of exposure to traditional heating and cooking sources, adjusting for a number of covariates, including smoking. Among men, there was no indication of excess risks. Among women, the odds ratio for those exposed to both traditional heating and cooking sources was 2.5 (95% confidence interval: 1.5, 3.6; n = 253). The findings for women suggest the need for research dedicated to exploring this association, with particular emphasis on improved exposure assessment.

  15. Emergy Evaluation of Dwelling Operation in Five Housing Units of Montreal Island, Canada

    Directory of Open Access Journals (Sweden)

    Ricardo Enrique Vega-Azamar

    2017-04-01

    Full Text Available Sustainability of cities and the environmental implications of high resource utilization by the domestic sector are growing concerns related to urban regions. Well-informed urban planning decision-making is an essential tool to help in the task and, for that, an important point to consider is the influence of parameters like residential density and housing typology on the intensity of resource utilization. Emergy synthesis, a life-cycle energy analysis methodological approach that considers the interaction of natural and human-made flows, was used to evaluate the environmental support for dwelling operational stage in five typical present-day housing units on the island of Montreal. As expected, resource utilization, measured as total emergy used, was positively correlated to housing unit size both with respect to number of occupants and dwelling size. Results suggest that variables affecting notably the intensity of resource utilization are per household income and per dweller habitable space and, while a higher income increased per capita emergy in all cases, increasing space availability per resident did not result in a decrease of empower density after 50 m2/person. Future work should consider lower and higher densities and analyses at the scale of blocks, neighborhoods and urban planning zones.

  16. Cross-Cultural Applicability of the Montreal Cognitive Assessment (MoCA): A Systematic Review.

    Science.gov (United States)

    O'Driscoll, Ciarán; Shaikh, Madiha

    2017-01-01

    The Montreal Cognitive Assessment (MoCA) is widely used to screen for mild cognitive impairment (MCI). While there are many available versions, the cross-cultural validity of the assessment has not been explored sufficiently. We aimed to interrogate the validity of the MoCA in a cross-cultural context: in differentiating MCI from normal controls (NC); and identifying cut-offs and adjustments for age and education where possible. This review sourced a wide range of studies including case-control studies. In addition, we report findings for differentiating dementias from NC and MCI from dementias, however, these were not considered to be an appropriate use of the MoCA. The subject of the review assumes heterogeneity and therefore meta-analyses was not conducted. Quality ratings, forest plots of validated studies (sensitivity and specificity) with covariates (suggested cut-offs, age, education and country), and summary receiver operating characteristic curve are presented. The results showed a wide range in suggested cutoffs for MCI cross-culturally, with variability in levels of sensitivity and specificity ranging from low to high. Poor methodological rigor appears to have affected reported accuracy and validity of the MoCA. The review highlights the necessity for cross-cultural considerations when using the MoCA, and recognizing it as a screen and not a diagnostic tool. Appropriate cutoffs and point adjustments for education are suggested.

  17. Sustainability Assessment of the Residential Land Use in Seven Boroughs of the Island of Montreal, Canada

    Directory of Open Access Journals (Sweden)

    Ricardo Enrique Vega-Azamar

    2015-02-01

    Full Text Available High resource utilization in the residential sector, and the associated environmental impacts, are central issues in the growth of urban regions. Land-use urban planning is a primary instrument for the proper development of cities; an important point is the consideration of the urban form’s influence on resource utilization intensity. Emergy synthesis, an energy-based methodological approach that allows the quantification and integration of both natural and human-generated flows interacting in urban environments, was used to assess sustainability of the residential land use of seven boroughs on the Island of Montreal. Natural resources, food, water, acquired goods and services, electricity and fuels were the main flows considered in the analysis. Results suggest that income, household size and distance to downtown are the variables affecting resource utilization intensity more noticeably and that allocation of green area coverage is an important parameter for controlling land use intensity. With the procedure used for calculating resource use intensity in the seven boroughs, it is possible to generate a tool to support urban planning decision-making for assessing sustainable development scenarios. Future research should consider urban green space potential for accommodating local waste treatment systems, acting as a greenhouse gas emissions sink and promoting human health.

  18. Validation of Montreal Cognitive Assessment-Basic in a sample of elderly Egyptians with neurocognitive disorders.

    Science.gov (United States)

    Saleh, Alia Adel; Alkholy, Rasha Saad Abd El Hamid Ali; Khalaf, Ola Osama; Sabry, Noha Ahmed; Amer, Hanan; El-Jaafary, Shaimaa; Khalil, Mohamed Abd El Fatah

    2018-02-09

    Montreal Cognitive Assessment-Basic (MoCA-B) is a modified version of the MoCA that is especially suitable for use in elderly subjects with low education. The Authors translated the tool into Arabic and they aimed at validation of this tool in a sample of elderly Egyptians. The study included 93 patients, 60 years and older, fulfilling the DSM-5 criteria of Mild Neurocognitive Disorder (NCD) (39 patients) and Major Neurocognitive Disorder (54 patients) that were compared to 112 community dwelling elder subjects. All subjects were assessed using the MoCA-B, Mini-Mental State Examination (MMSE), and the Clinical Dementia Rating Scale (CDR) in addition to the required laboratory and radiological investigations. MoCA-B demonstrated good internal consistency (Cronbach's alpha = 0.915) and content validity in discrimination between normal and diseased subjects. It showed superior sensitivity and specificity when compared to MMSE in screening for Mild NCD (AUC MoCA-B = 0.988 versus MMSE = 0.939). The recommended cut-off was 21/22 with sensitivity of 92.5% and specificity of 98.2% for detecting Mild NCD and 16/17 with sensitivity of 90.7% and specificity of 97.4% for detecting Major NCD (dementia). The Arabic MoCA-B is a valid cognitive assessment tool in elderly Egyptian subjects.

  19. Psychic centrality: reflections on two psychohistoriographic cultural therapy workshops in Montreal.

    Science.gov (United States)

    Hickling, Frederick W; Guzder, Jaswant; Robertson-Hickling, Hilary; Snow, Stephen; Kirmayer, Laurence J

    2010-02-01

    The use of psychohistoriographic cultural therapy (PCT) developed in Jamaica is described in the context of two workshops in Montreal. PCT is a form of group intervention that seeks to elicit and clarify the "psychic centrality" of a group. Psychic centrality refers to a sense of psychological containment or organization of diverse individual points of view through creating a historical map of collective experience. In PCT, this collective map is constructed and techniques borrowed from creative arts therapies are used to develop a performance. This performance provides additional containment and fosters a group process that can contain collective conflicts. The performance can also be used to engage an audience, working to contain conflict while representing diverse perspectives within the group. Factors that may contribute to the effectiveness of PCT and those that may derail the process are identified through the systematic comparison of the two workshops. PCT was demonstrated to cross successfully from a Third to a First World culture, and established potential as a method to facilitate group conflict resolution and for the promotion of pluralistic civil societies.

  20. Normative Data of the Montreal Cognitive Assessment in the Greek Population and Parkinsonian Dementia.

    Science.gov (United States)

    Konstantopoulos, K; Vogazianos, P; Doskas, T

    2016-05-01

    The Montreal Cognitive Assessment (MoCA) is a brief cognitive instrument for the measurement of dementia. The aim of the present study is to provide normative data for the MoCA test in the Greek speaking population and to measure its validity in a clinical group of parkinsonian dementia participants. A total of 710 healthy Greek speaking participants and 19 parkinsonian dementia participants took part in the study. Both, the MoCA test and a neuropsychological test battery (digit span, semantic verbal fluency, phonemic verbal fluency, Color Trails Test) were administered to the normative and clinical samples. The test was found to correlate with all neuropsychological tests used in the test battery and it showed high discriminant validity (optimal screening cutoff point = 21, sensitivity = 0.82, specificity = 0.90) in the parkinsonian dementia participants. Further research is needed to use it in larger clinical samples and in different neurological diseases. © The Author 2016. Published by Oxford University Press. All rights reserved. For permissions, please e-mail: journals.permissions@oup.com.

  1. Effects of Montreal municipal sewage effluents on immune responses of juvenile female rainbow trout (Oncorhynchus mykiss)

    Energy Technology Data Exchange (ETDEWEB)

    Salo, Harri M. [INRS-institut Armand-Frappier, 245 Hymus Boul., Pointe-Claire, Que. H9R 1G6 (Canada)], E-mail: harri.salo@ktl.fi; Hebert, Nancy; Dautremepuits, Claire [INRS-institut Armand-Frappier, 245 Hymus Boul., Pointe-Claire, Que. H9R 1G6 (Canada); Cejka, Patrick [Montreal Wastewater Treatment Plant, 12 001 Maurice-Duplessis, Montreal, Que. H1C 1V3 (Canada); Cyr, Daniel G.; Fournier, Michel [INRS-institut Armand-Frappier, 245 Hymus Boul., Pointe-Claire, Que. H9R 1G6 (Canada)

    2007-10-30

    The objective of this study was to examine the immunotoxicity of treated Montreal sewage effluents on juvenile female rainbow trout (Oncorhynchus mykiss). A comprehensive panel of immunological assays was used to evaluate the effects of exposure for 1 and 4 weeks to 1, 3, 10 and 20% sewage effluent. Phagocytic ingestion of fluorescent latex beads by head kidney macrophages and granulocytes was suppressed following 1-week of exposure, with the highest exposure concentration being the most suppressive. Phagocytic activity returned to control levels after 4 weeks of exposure. The cytotoxic activity of head kidney derived non-specific cytotoxic cells was enhanced after a 1-week exposure, especially at the lowest exposure concentration, and returned to control levels after 4 weeks of exposure. In vitro lymphocyte proliferation in response to LPS and ConA activation was not affected following sewage effluent exposure, but nonactivated, spontaneous proliferation of lymphocytes was suppressed in a dose-dependent manner after 4 weeks of exposure. Plasma lysozyme activity was elevated at lowest exposure concentration after 4 weeks. No changes were noted in either the blood leukocyte/erythrocyte ratio or in the proportion of circulating lymphocytes and thrombocytes. The proportion of circulating granulocytes increased following exposure for 4 weeks to the low effluent concentration. Plasma cortisol levels were not affected by effluent exposure suggesting that mechanisms other than stress influenced the observed immunomodulation. In summary, this study demonstrates that sewage effluent can alter the immune functions of rainbow trout.

  2. Sleep Disturbance from Road Traffic, Railways, Airplanes and from Total Environmental Noise Levels in Montreal.

    Science.gov (United States)

    Perron, Stéphane; Plante, Céline; Ragettli, Martina S; Kaiser, David J; Goudreau, Sophie; Smargiassi, Audrey

    2016-08-11

    The objective of our study was to measure the impact of transportation-related noise and total environmental noise on sleep disturbance for the residents of Montreal, Canada. A telephone-based survey on noise-related sleep disturbance among 4336 persons aged 18 years and over was conducted. LNight for each study participant was estimated using a land use regression (LUR) model. Distance of the respondent's residence to the nearest transportation noise source was also used as an indicator of noise exposure. The proportion of the population whose sleep was disturbed by outdoor environmental noise in the past 4 weeks was 12.4%. The proportion of those affected by road traffic, airplane and railway noise was 4.2%, 1.5% and 1.1%, respectively. We observed an increased prevalence in sleep disturbance for those exposed to both rail and road noise when compared for those exposed to road only. We did not observe an increased prevalence in sleep disturbance for those that were both exposed to road and planes when compared to those exposed to road or planes only. We developed regression models to assess the marginal proportion of sleep disturbance as a function of estimated LNight and distance to transportation noise sources. In our models, sleep disturbance increased with proximity to transportation noise sources (railway, airplane and road traffic) and with increasing LNight values. Our study provides a quantitative estimate of the association between total environmental noise levels estimated using an LUR model and sleep disturbance from transportation noise.

  3. Effects of Montreal municipal sewage effluents on immune responses of juvenile female rainbow trout (Oncorhynchus mykiss)

    International Nuclear Information System (INIS)

    Salo, Harri M.; Hebert, Nancy; Dautremepuits, Claire; Cejka, Patrick; Cyr, Daniel G.; Fournier, Michel

    2007-01-01

    The objective of this study was to examine the immunotoxicity of treated Montreal sewage effluents on juvenile female rainbow trout (Oncorhynchus mykiss). A comprehensive panel of immunological assays was used to evaluate the effects of exposure for 1 and 4 weeks to 1, 3, 10 and 20% sewage effluent. Phagocytic ingestion of fluorescent latex beads by head kidney macrophages and granulocytes was suppressed following 1-week of exposure, with the highest exposure concentration being the most suppressive. Phagocytic activity returned to control levels after 4 weeks of exposure. The cytotoxic activity of head kidney derived non-specific cytotoxic cells was enhanced after a 1-week exposure, especially at the lowest exposure concentration, and returned to control levels after 4 weeks of exposure. In vitro lymphocyte proliferation in response to LPS and ConA activation was not affected following sewage effluent exposure, but nonactivated, spontaneous proliferation of lymphocytes was suppressed in a dose-dependent manner after 4 weeks of exposure. Plasma lysozyme activity was elevated at lowest exposure concentration after 4 weeks. No changes were noted in either the blood leukocyte/erythrocyte ratio or in the proportion of circulating lymphocytes and thrombocytes. The proportion of circulating granulocytes increased following exposure for 4 weeks to the low effluent concentration. Plasma cortisol levels were not affected by effluent exposure suggesting that mechanisms other than stress influenced the observed immunomodulation. In summary, this study demonstrates that sewage effluent can alter the immune functions of rainbow trout

  4. Use of a new public bicycle share program in Montreal, Canada.

    Science.gov (United States)

    Fuller, Daniel; Gauvin, Lise; Kestens, Yan; Daniel, Mark; Fournier, Michel; Morency, Patrick; Drouin, Louis

    2011-07-01

    Cycling contributes to physical activity and health. Public bicycle share programs (PBSPs) increase population access to bicycles by deploying bicycles at docking stations throughout a city. Minimal research has systematically examined the prevalence and correlates of PBSP use. To determine the prevalence and correlates of use of a new public bicycle share program called BIXI (name merges the word BIcycle and taXI) implemented in May 2009 in Montreal, Canada. A total of 2502 adults were recruited to a telephone survey in autumn 2009 via random-digit dialing according to a stratified random sampling design. The prevalence of BIXI bicycle use was estimated. Multivariate logistic regression allowed for identification of correlates of use. Data analysis was conducted in spring and summer 2010. The unweighted mean age of respondents was 47.4 (SD=16.8) years and 61.4% were female. The weighted prevalence for use of BIXI bicycles at least once was 8.2%. Significant correlates of BIXI bicycle use were having a BIXI docking station within 250 m of home, being aged 18-24 years, being university educated, being on work leave, and using cycling as the primary mode of transportation to work. A newly implemented public bicycle share program attracts a substantial fraction of the population and is more likely to attract younger and more educated people who currently use cycling as a primary transportation mode. Copyright © 2011 American Journal of Preventive Medicine. Published by Elsevier Inc. All rights reserved.

  5. The Geography of Clusters: The Case of the Video Games Clusters in Montreal and in Los Angeles

    Directory of Open Access Journals (Sweden)

    Sylvianne Pilon

    2013-01-01

    Full Text Available The aim of our research was to examine how clusters appear and develop in the video game sector. We thus did a comparative study of the video games cluster in Montreal and Los Angeles. This paper shows that concentration of human creativity in arts and in technology is a significant economic localization factor, but cross-fertilization of sectors and public policy also contributes to the understanding of the emergence of clusters in certain urban regions. Thus, political and industrial factors offer an explanation as to why clusters emerge and how they evolve, going beyond the purely geographic or economic factors. In LA as in Montreal, the cross-fertilization with film is important. However, in Montreal, it is the public policy contributing to financing jobs in the Multimedia City and the French language that brought Ubisoft to the city; this contributed to make the city well known in the field, creating a “brand” for the city and thus fuelling the cluster development.

  6. An ASM/ADM model interface for dynamic plant-wide simulation.

    Science.gov (United States)

    Nopens, Ingmar; Batstone, Damien J; Copp, John B; Jeppsson, Ulf; Volcke, Eveline; Alex, Jens; Vanrolleghem, Peter A

    2009-04-01

    Mathematical modelling has proven to be very useful in process design, operation and optimisation. A recent trend in WWTP modelling is to include the different subunits in so-called plant-wide models rather than focusing on parts of the entire process. One example of a typical plant-wide model is the coupling of an upstream activated sludge plant (including primary settler, and secondary clarifier) to an anaerobic digester for sludge digestion. One of the key challenges when coupling these processes has been the definition of an interface between the well accepted activated sludge model (ASM1) and anaerobic digestion model (ADM1). Current characterisation and interface models have key limitations, the most critical of which is the over-use of X(c) (or lumped complex) variable as a main input to the ADM1. Over-use of X(c) does not allow for variation of degradability, carbon oxidation state or nitrogen content. In addition, achieving a target influent pH through the proper definition of the ionic system can be difficult. In this paper, we define an interface and characterisation model that maps degradable components directly to carbohydrates, proteins and lipids (and their soluble analogues), as well as organic acids, rather than using X(c). While this interface has been designed for use with the Benchmark Simulation Model No. 2 (BSM2), it is widely applicable to ADM1 input characterisation in general. We have demonstrated the model both hypothetically (BSM2), and practically on a full-scale anaerobic digester treating sewage sludge.

  7. Isolation and characterization of plantaricin ASM1: a new bacteriocin produced by Lactobacillus plantarum A-1.

    Science.gov (United States)

    Hata, Tomomi; Tanaka, Rie; Ohmomo, Sadahiro

    2010-01-31

    Bacteriocins produced by lactic acid bacteria showing stability even in neutral and weak alkaline pH were screened, and a new bacteriocin produced by Lactobacillus plantarum A-1, plantaricin ASM1 (PASM1) was purified and characterized. This bacteriocin which is heat-stable but digested by trypsin inhibits the growth of lactic acid bacterial species, such as Lactobacillus, Leuconostoc, and Enterococcus. PASM1 showed stability in a wide pH range compared to nisin A. The bacteriocin was purified using cation exchange, hydrophobic interaction, and reverse-phase high-performance liquid chromatography. The activity of the purified bacteriocin was obtained as one fraction. Matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis of the fraction showed a mass of 5045.7Da. Combining the data obtained from amino acid and DNA sequencing, the primary sequence of PASM1 was determined. The sequence of the corresponding gene revealed that the peptide is ribosomally synthesized as a 64 amino acid precursor containing a 21 amino acid N-terminal extension of the double-glycine type. The mature peptide consists of 43 amino acids, which could contain two intramolecular disulfide bonds in the structure. Three putative open reading frames were located upstream of the PLNA1 gene. These genes may encode the thioredoxin family proteins and a response regulator both of which have been suggested to regulate expression of the PASM1 gene and the processing of its leader peptide. PASM1 has no reported homologue bacteriocins. Stability in a wide pH range and heat indicates its potential for application in food preservation. Copyright 2009 Elsevier B.V. All rights reserved.

  8. Fire effects on prehistoric ceramics [Chapter 3

    Science.gov (United States)

    Trisha Rude; Anne Trinkle Jones

    2012-01-01

    In North America, prehistoric pottery is primarily earthenware (a porous ceramic, fired at a relatively low temperature). It is not glass-like or dense like other kinds of pottery such as stoneware and porcelain (see chapter 6).

  9. The reinvigorated South African GRSS Chapter

    CSIR Research Space (South Africa)

    Schwegmann, Colin P

    2017-09-01

    Full Text Available Looking ahead, the South African GRSS Chapter is investigating the possibility of organizing a meeting with local GRSS members, universities, and other remote-sensing organizations with the purpose of engaging undergraduate and early postgraduate...

  10. Chapter 42. Waterborne and Foodborne Parasites

    Science.gov (United States)

    This chapter identifies the most prominent parasites in North America that are acquired through contaminated food and water including protozoa (Acanthamoeba, Naegleria, Entamoeba, Giardia, Cryptosporidium, Cystoisospora, Cyclospora, Toxoplasma, and Balantidium), nematodes (Trichinella, Angiostrongyl...

  11. The Innovation in Libraries Awesome Foundation Chapter

    Directory of Open Access Journals (Sweden)

    Joshua Finnell

    2017-05-01

    Full Text Available In Brief: This article discusses the creation, philosophy, and future directions of the Innovation in Libraries Awesome Foundation Chapter, a grassroots crowdfunding initiative incubated within Library Pipeline.

  12. Chapter 5: Summary of model application

    International Nuclear Information System (INIS)

    1995-01-01

    This chapter provides a brief summary of the model applications described in Volume III of the Final Report. This chapter dealt with the selected water management regimes; ground water flow regimes; agriculture; ground water quality; hydrodynamics, sediment transport and water quality in the Danube; hydrodynamics, sediment transport and water quality in the river branch system; hydrodynamics, sediment transport and water quality in the Hrusov reservoir and with ecology in this Danube area

  13. 106-17 Telemetry Management Resources Chapter 25

    Science.gov (United States)

    2017-07-01

    capable of generating event -based notifications. Management resources regarding general notifications are contained within the...Telemetry Standards, RCC Standard 106-17 Chapter 25, July 2017 i CHAPTER 25 Management Resources Acronyms...iii Chapter 25. Management Resources

  14. Effects of ASM-024, a modulator of acetylcholine receptor function, on airway responsiveness and allergen-induced responses in patients with mild asthma.

    Science.gov (United States)

    Boulet, Louis-Philippe; Gauvreau, Gail M; Cockcroft, Donald W; Davis, Beth; Vachon, Luc; Cormier, Yvon; O'Byrne, Paul M

    2015-01-01

    To evaluate the safety, tolerability and clinical activity of ASM-024, a new cholinergic compound with dual nicotinic and muscarinic activity, in mild allergic asthma. The present study involved 24 stable, mild allergic asthmatic subjects. In a cross-over design, ASM-024 (50 mg or 200 mg) or placebo were administered once daily by nebulization over three periods of nine consecutive days separated by a three-week washout. The effect of each treatment on the forced expiratory volume in 1 s (FEV1), provocative concentration of methacholine causing a 20% decline in FEV1 (PC20), early and late asthmatic responses, and allergen-induced inflammation were measured. Seventeen subjects completed the study. During treatment with ASM-024 at 50 mg or 200 mg, the PC20 value increased respectively from a mean (± SD) 2.56±3.86 mg/mL to 4.11 mg/mL (P=0.007), and from 3.12±4.37 mg/mL to 5.23 mg/mL (P=0.005) (no change with placebo). On day 7 (day preceding allergen challenge), postdosing FEV1 increased by 2.0% with 50 mg (P=0.005) and 1.9% with 200 mg (P=0.008) (placebo -1.1%). ASM-24 had no inhibitory effect on early and late asthmatic responses, nor on sputum eosinophil or neutrophil levels. ASM-024 induced no serious adverse events, but caused cough in 22% and 48% of the subjects with 50 mg and 200 mg, respectively, compared with 10% who were on placebo. ASM-024 did not inhibit allergen-induced asthmatic response and related airway inflammation, but reduced methacholine airway responsiveness and slightly improved lung function. The mechanism by which ASM-024 improves these outcomes requires further study.

  15. Towards a consensus-based biokinetic model for green microalgae - The ASM-A.

    Science.gov (United States)

    Wágner, Dorottya S; Valverde-Pérez, Borja; Sæbø, Mariann; Bregua de la Sotilla, Marta; Van Wagenen, Jonathan; Smets, Barth F; Plósz, Benedek Gy

    2016-10-15

    Cultivation of microalgae in open ponds and closed photobioreactors (PBRs) using wastewater resources offers an opportunity for biochemical nutrient recovery. Effective reactor system design and process control of PBRs requires process models. Several models with different complexities have been developed to predict microalgal growth. However, none of these models can effectively describe all the relevant processes when microalgal growth is coupled with nutrient removal and recovery from wastewaters. Here, we present a mathematical model developed to simulate green microalgal growth (ASM-A) using the systematic approach of the activated sludge modelling (ASM) framework. The process model - identified based on a literature review and using new experimental data - accounts for factors influencing photoautotrophic and heterotrophic microalgal growth, nutrient uptake and storage (i.e. Droop model) and decay of microalgae. Model parameters were estimated using laboratory-scale batch and sequenced batch experiments using the novel Latin Hypercube Sampling based Simplex (LHSS) method. The model was evaluated using independent data obtained in a 24-L PBR operated in sequenced batch mode. Identifiability of the model was assessed. The model can effectively describe microalgal biomass growth, ammonia and phosphate concentrations as well as the phosphorus storage using a set of average parameter values estimated with the experimental data. A statistical analysis of simulation and measured data suggests that culture history and substrate availability can introduce significant variability on parameter values for predicting the reaction rates for bulk nitrate and the intracellularly stored nitrogen state-variables, thereby requiring scenario specific model calibration. ASM-A was identified using standard cultivation medium and it can provide a platform for extensions accounting for factors influencing algal growth and nutrient storage using wastewater resources. Copyright

  16. Velódromo Olímpico de Montreal – Canadá

    Directory of Open Access Journals (Sweden)

    Taillibert, Roger

    1976-12-01

    Full Text Available This stadium is one of the most interesting ones that have been constructed lately. It has the following basic conditions: harmonious integration with the other Olympic installations; possibilities for future enlargements; total absence of supports; perfect permeability for the natural daylight; and perfect insulations in view of the hard climate of Montreal. Bearing these features in mind, the building consists of two parts: — The velodrome itself with lawn; 285.70 m long and 7.50 m wide courses with a slope varying between 18° and 48° with regard to the horizontal line; gallery for the public; auxiliary premises; dressing rooms, etc. — And the regular spheric roof the plan form of which represents three segments beginning with one buttress in the northeast end and increasing to three buttresses in the southeast end. This entirely self-supporting dome is 172 m long with a maximum height of 32 m. The total surface is 15,000 m2. The work was calculated by means of computers and was carried out with prefabricated pieces of concrete so as to achieve a better quality control of the concrete, and above all, a greater exactness of the prefabricated members. This was an indispensable factor in this case, where the maximum admissible error in most of the pieces was only 1.5 mm.Es uno de los estadios más interesantes de los últimos tiempos, con las siguientes condiciones básicas: armónica integración con las restantes instalaciones olímpicas; posibilidad de transformación para futuras aplicaciones; total ausencia de soportes; amplia permeabilidad a la luz natural; y perfecta estanquidad ante las duras condiciones climáticas de Montreal. Partiendo de estas premisas, el edificio consta de dos partes: — El velódromo propiamente dicho, con: césped; pista de carreras de 285,70 m de desarrollo, 7,50 m de anchura e inclinación variable entre 18° y 48° respecto a la horizontal; gradas para el público; locales auxiliares

  17. Latent segmentation based count models: Analysis of bicycle safety in Montreal and Toronto.

    Science.gov (United States)

    Yasmin, Shamsunnahar; Eluru, Naveen

    2016-10-01

    The study contributes to literature on bicycle safety by building on the traditional count regression models to investigate factors affecting bicycle crashes at the Traffic Analysis Zone (TAZ) level. TAZ is a traffic related geographic entity which is most frequently used as spatial unit for macroscopic crash risk analysis. In conventional count models, the impact of exogenous factors is restricted to be the same across the entire region. However, it is possible that the influence of exogenous factors might vary across different TAZs. To accommodate for the potential variation in the impact of exogenous factors we formulate latent segmentation based count models. Specifically, we formulate and estimate latent segmentation based Poisson (LP) and latent segmentation based Negative Binomial (LNB) models to study bicycle crash counts. In our latent segmentation approach, we allow for more than two segments and also consider a large set of variables in segmentation and segment specific models. The formulated models are estimated using bicycle-motor vehicle crash data from the Island of Montreal and City of Toronto for the years 2006 through 2010. The TAZ level variables considered in our analysis include accessibility measures, exposure measures, sociodemographic characteristics, socioeconomic characteristics, road network characteristics and built environment. A policy analysis is also conducted to illustrate the applicability of the proposed model for planning purposes. This macro-level research would assist decision makers, transportation officials and community planners to make informed decisions to proactively improve bicycle safety - a prerequisite to promoting a culture of active transportation. Copyright © 2016 Elsevier Ltd. All rights reserved.

  18. Evaluating the relationship between education level and cognitive impairment with the Montreal Cognitive Assessment Test.

    Science.gov (United States)

    Yancar Demir, Esra; Özcan, Tuba

    2015-09-01

    Mild cognitive impairment (MCI) is defined as 'a cognitive decline greater than that expected for an individual's age and education level but that does not interfere notably with activities of daily life'. The Montreal Cognitive Assessment (MoCA) is a screening test for MCI. We investigated the performance of the Turkish version of the MoCA in detecting MCI among elderly persons in a rural area, the majority of whom have a low level of education. We evaluated 50 consecutive men referred from an outpatient clinic. Educational level was divided into three categories: group 1, less than primary (5 years). We evaluated the effect of education on MoCA scores and compared subjects' test performance among the different categories of education level. A total of 50 male patients with MCI (mean age: 70.74 ± 7.87) met the inclusion criteria. There were no differences in the total scores based on education or in the subscores for visuospatial/executive function, naming, attention, abstraction and delayed recall. Language was the only domain that showed significant differences between the groups. In post-hoc analysis, differences were found between groups 1 and 3 and between groups 1 and 2. Group 1 had significantly lower scores for language. The repeat subscore for language was significantly lower in group 1 than in group 2. In fluency, there were significant differences between groups 2 and 3 and between group 1 and 3. To our knowledge, this is the first study to analyze the applicability of the Turkish version of MoCA in populations with little education. Our results emphasize the need to adapt the language sections of this test, so it can be easily used in populations with low education levels. © 2014 The Authors. Psychogeriatrics © 2014 Japanese Psychogeriatric Society.

  19. Revising the diagnosis of congenital amusia with the Montreal Battery of Evaluation of Amusia.

    Science.gov (United States)

    Pfeifer, Jasmin; Hamann, Silke

    2015-01-01

    This article presents a critical survey of the prevalent usage of the Montreal Battery of Evaluation of Amusia (MBEA; Peretz et al., 2003) to assess congenital amusia, a neuro-developmental disorder that has been claimed to be present in 4% of the population (Kalmus and Fry, 1980). It reviews and discusses the current usage of the MBEA in relation to cut-off scores, number of used subtests, manner of testing, and employed statistics, as these vary in the literature. Furthermore, data are presented from a large-scale experiment with 228 German undergraduate students who were assessed with the MBEA and a comprehensive questionnaire. This experiment tested the difference between scores that were obtained in a web-based study (at participants' homes) and those obtained under laboratory conditions with a computerized version of the MBEA. In addition to traditional statistical procedures, the data were evaluated using Signal Detection Theory (SDT; Green and Swets, 1966), taking into consideration the individual's ability to discriminate and their response bias. Results show that using SDT for scoring instead of proportion correct offers a bias-free and normally distributed measure of discrimination ability. It is also demonstrated that a diagnosis based on an average score leads to cases of misdiagnosis. The prevalence of congenital amusia is shown to depend highly on the statistical criterion that is applied as cut-off score and on the number of subtests that is considered for the diagnosis. In addition, three different subtypes of amusics were found in our sample. Lastly, significant differences between the web-based and the laboratory group were found, giving rise to questions about the validity of web-based experimentation.

  20. Revising the diagnosis of congenital amusia with the Montreal Battery of Evaluation of Amusia

    Directory of Open Access Journals (Sweden)

    Jasmin ePfeifer

    2015-04-01

    Full Text Available This article presents a critical survey of the prevalent usage of the Montreal Battery of Evaluation of Amusia (MBEA; Peretz et al., 2003 to assess congenital amusia, a neuro-developmental disorder that has been claimed to be present in 4% of the population (Kalmus and Fry, 1980. It reviews and discusses the current usage of the MBEA in relation to cut-off scores, number of used subtests, manner of testing, and employed statistics, as these vary in the literature. Furthermore, data are presented from a large-scale experiment with 228 German undergraduate students who were assessed with the MBEA and a comprehensive questionnaire. This experiment tested the difference between scores that were obtained in a web-based study (at participants’ homes and those obtained under laboratory conditions with a computerized version of the MBEA. In addition to traditional statistical procedures, the data were evaluated using Signal Detection Theory (SDT; Green and Swets, 1966, taking into consideration the individual’s ability to discriminate and their response bias. Results show that using SDT for scoring instead of proportion correct offers a bias-free and normally distributed measure of discrimination ability. In addition it is also demonstrated that a diagnosis based on an average score leads to cases of misdiagnosis. The prevalence of congenital amusia is shown to depend highly on the statistical criterion that is applied as cut-off score and on the number of subtests that is considered for the diagnosis. In addition, three different subtypes of amusics were found in our sample. Lastly, significant differences between the web-based and the laboratory group were found, giving rise to questions about the validity of web-based experimentation.

  1. Revising the diagnosis of congenital amusia with the Montreal Battery of Evaluation of Amusia

    Science.gov (United States)

    Pfeifer, Jasmin; Hamann, Silke

    2015-01-01

    This article presents a critical survey of the prevalent usage of the Montreal Battery of Evaluation of Amusia (MBEA; Peretz et al., 2003) to assess congenital amusia, a neuro-developmental disorder that has been claimed to be present in 4% of the population (Kalmus and Fry, 1980). It reviews and discusses the current usage of the MBEA in relation to cut-off scores, number of used subtests, manner of testing, and employed statistics, as these vary in the literature. Furthermore, data are presented from a large-scale experiment with 228 German undergraduate students who were assessed with the MBEA and a comprehensive questionnaire. This experiment tested the difference between scores that were obtained in a web-based study (at participants’ homes) and those obtained under laboratory conditions with a computerized version of the MBEA. In addition to traditional statistical procedures, the data were evaluated using Signal Detection Theory (SDT; Green and Swets, 1966), taking into consideration the individual’s ability to discriminate and their response bias. Results show that using SDT for scoring instead of proportion correct offers a bias-free and normally distributed measure of discrimination ability. It is also demonstrated that a diagnosis based on an average score leads to cases of misdiagnosis. The prevalence of congenital amusia is shown to depend highly on the statistical criterion that is applied as cut-off score and on the number of subtests that is considered for the diagnosis. In addition, three different subtypes of amusics were found in our sample. Lastly, significant differences between the web-based and the laboratory group were found, giving rise to questions about the validity of web-based experimentation. PMID:25883562

  2. Evaluation of the integrity of reactor vessels designed to ASME Code, Sections I and/or VIII

    International Nuclear Information System (INIS)

    Hoge, K.G.

    1976-01-01

    A documented review of nuclear reactor pressure vessels designed to ASME Code, Sections I and/or VIII is made. The review is primarily concerned with the design specifications and quality assurance programs utilized for the reactor vessel construction and the status of power plant material surveillance programs, pressure-temperature operating limits, and inservice inspection programs. The following ten reactor vessels for light-water power reactors are covered in the report: Indian Point Unit No. 1, Dresden Unit No. 1, Yankee Rowe, Humboldt Bay Unit No. 3, Big Rock Point, San Onofre Unit No. 1, Connecticut Yankee, Oyster Creek, Nine Mile Point Unit No. 1, and La Crosse

  3. Comparisons of ASME-code fatigue-evaluation methods for nuclear Class 1 piping with Class 2 or 3 piping

    International Nuclear Information System (INIS)

    Rodabaugh, E.C.

    1983-06-01

    The fatigue evaluation procedure used in the ASME Boiler and Pressure Vessel Code, Sect. III, Nuclear Power Plant Components, for Class 1 piping is different from the procedure used for Class 2 or 3 piping. The basis for each procedure is described, and correlations between the two procedures are presented. Conditions under which either procedure or both may be unconservative are noted. Potential changes in the Class 2 or 3 piping procedure to explicitly cover all loadings are discussed. However, the report is intended to be informative, and while the contents of the report may guide future Code changes, specific recommendations are not given herein

  4. Acid sphingomyelinase (Asm) deficiency patients in The Netherlands and Belgium: disease spectrum and natural course in attenuated patients.

    Science.gov (United States)

    Hollak, C E M; de Sonnaville, E S V; Cassiman, D; Linthorst, G E; Groener, J E; Morava, E; Wevers, R A; Mannens, M; Aerts, J M F G; Meersseman, W; Akkerman, E; Niezen-Koning, K E; Mulder, M F; Visser, G; Wijburg, F A; Lefeber, D; Poorthuis, B J H M

    2012-11-01

    Niemann-Pick disease (NPD) is a neurovisceral lysosomal storage disorder caused by acid sphingomyelinase (ASM) deficiency, which can be categorized as either Niemann-Pick disease type A [NPD-A], with progressive neurological disease and death in early childhood, or as Niemann-Pick disease type B [NPD-B], with a more variable spectrum of manifestations. Enzyme replacement therapy (ERT) with recombinant sphingomyelinase is currently studied as potential treatment for NPD-B patients. The objective of this study is to characterize the clinical features of patients with ASM deficiency in the Netherlands and Belgium with focus on the natural disease course of NPD-B patients. Prospective and retrospective data on ASM deficient patients were collected in The Netherlands and part of Belgium. Patients with NPD-B that could be followed prospectively were evaluated every 6-12 months for pulmonary function tests, 6 minute walk test (6 MWT), imaging (bone marrow infiltration measured by QCSI, organ volumes by MRI and CT scan of the lungs) and biochemical markers. Twenty-five patients with ASM deficiency were identified (13 males, 12 females, median age 13years, range 1-59 years). Nine patients had died at the time of the study, including four NPD-A patients at the age of 1,1, 2, 3 and five NPDB patents at the age of 5, 6, 43, 56 and 60 years. There was a high prevalence of homozygosity and compound heterozygosity for the common p.Arg608del mutation in 43% and 19% of NPD-B patients, respectively. In NPD-B patients, thrombocytopenia was present in most, while anemia and leucopenia were less common (33% and 6 % respectively). HDL cholesterol was reduced in most patients. Pulmonary disease was severe in several patients. Follow-up up to 11 years revealed a gradual decrease in platelet count. Detailed investigations in 6 NPD-B patients with follow-up in 4 patients revealed remarkable stable disease parameters up to 6 years, with some decline in pulmonary function and 6 MWT. Bone

  5. A Grand Gender Convergence: Its Last Chapter

    OpenAIRE

    Claudia Goldin

    2014-01-01

    The converging roles of men and women are among the grandest advances in society and the economy in the last century. These aspects of the grand gender convergence are figurative chapters in a history of gender roles. But what must the "last" chapter contain for there to be equality in the labor market? The answer may come as a surprise. The solution does not (necessarily) have to involve government intervention and it need not make men more responsible in the home (although that wouldn't hur...

  6. Comparative studies on the effects of a yucca extract and acibenzolar-S-methyl (ASM) on inhibition of Venturia inaequalis in apple leaves

    DEFF Research Database (Denmark)

    Bengtsson, Marianne Vibeke; Wulff, Ednar Gadelha; Jørgensen, Hans Jørgen Lyngs

    2009-01-01

    and pathogen sporulation on leaves and both showed similar control efficacies as the reference treatment, sulphur. Whereas yucca extract and sulphur gave significant inhibition of conidial germination in vitro, ASM did not inhibit germination. Histopathological studies of the infection process of V. inaequalis...... in apple leaves showed that the yucca extract primarily acted by inhibiting pre-penetration events and penetration itself. In contrast, the ASM treatment significantly inhibited more stages of the infection process (pre-penetration, penetration and post-penetration events). These observations suggest...... was up-regulated following yucca treatment, to a level similar to that observed after treatment with ASM. The fungitoxic effect of sulphur on V. inaequalis was also confirmed in this study....

  7. Influência das variáveis biopsicossociais na qualidade de vida em asmáticos

    Directory of Open Access Journals (Sweden)

    Ana Paula Soares de Matos

    Full Text Available A asma brônquica é uma doença complexa e interfere com a qualidade de vida desses doentes. Pretendemos, com a presente investigação, estudar a relação das variáveis sócio-demográficas (género, idade e grau de instrução, clínicas (gravidade da doença, duração e tipo clínico e psicológicas (cognições, emoções e comportamentos com a qualidade de vida do doente asmático. Cinqüenta doentes asmáticos do Departamento de Pneumologia e Imunoalergologia dos Hospitais da Universidade de Coimbra preencheram cinco questionários de auto-resposta que avaliavam as variáveis psicológicas em estudo. Os dados clínicos relativamente à doença foram igualmente recolhidos.Os nossos resultados revelam-nos que a qualidade de vida se relaciona com um conjunto de variáveis que podemos denominar biopsicossociais (e.g., uma menor qualidade de vida relaciona-se com uma maior idade, menor escolaridade, uma atitude mais negativa face à asma, designada "estigma", cognições disfuncionais e comportamentos/emoções-problema relacionados com a asma. Implicações ao nível do tratamento são apresentadas.

  8. Intervención educativa para población infanto-juvenil asmática

    Directory of Open Access Journals (Sweden)

    Maria Antonia Acevedo Veja

    2015-11-01

    Full Text Available Se realizó una intervención educativa a la población infanto-juvenil asmática con edades entre ocho y once años en el policlínico de Manatí, Las Tunas, entre enero y julio de 2012, con el objetivo de evaluar la eficacia de la misma. La población de estudio estuvo formada por los 258 pacientes asmáticos de los 29 Consultorios de Médico de Familia (CMF del área, y la muestra por los 50 seleccionados por muestreo aleatorio simple. La información se obtuvo mediante un cuestionario que fue aplicado antes y después de la intervención educativa y los datos fueron recogidos durante la consulta y de la historia clínica individual. Se concluyó que predominó el sexo masculino, con antecedentes de primera línea de asma bronquial, con factores desencadenantes tales como: infecciones respiratorias agudas, polvo y humedad, así como aquellos que presentan signos clínicos de reflujo y que tienen una mala técnica de aplicación de spray. Se apreció un insuficiente nivel de conocimientos sobre la evaluación de severidad de la crisis, los factores desencadenantes, el manejo del spray y el tratamiento intercrisis, y las exacerbaciones.

  9. Non Destructive Test Dye Penetrant and Ultrasonic on Welding SMAW Butt Joint with Acceptance Criteria ASME Standard

    Science.gov (United States)

    Endramawan, T.; Sifa, A.

    2018-02-01

    The purpose of this research is to know the type of discontinuity of SMAW welding result and to determine acceptance criteria based on American Society of Mechanical Engineer (ASME) standard. Material used is mild steel 98,71% Fe and 0,212% C with hardness 230 VHN with specimen diameter 20 cm and thickness 1.2 cm which is welded use SMAW butt joint with electrode for rooting LB 52U diameter 2.6 mm, current 70 Ampere and voltage 380 volt, filler used LB 5218 electrode diameter 3.2 mm with current 80 Ampere and 380 volt. The method used to analyze the welded with non destructive test dye penetrant (PT) method to see indication on the surface of the object and Ultrasonic (UT) to see indication on the sub and inner the surface of the object, the result is discontinuity recorded and analyzed and then the discontinuity is determine acceptance criteria based on the American Society of Mechanical Engineer (ASME) standards. The result show the discontinuity of porosity on the surface of the welded and inclusion on sub material used ultrasonic test, all indication on dye penetrant or ultrasonic test if there were rejected of result of welded that there must be gouging on part which rejected and then re-welding.

  10. An evaluation of the impact of FIFA World Cup on soccer emergency department injuries among Montreal adolescents.

    Science.gov (United States)

    Keays, Glenn; Friedman, Debbie; Beaudin, Marianne; Gagnon, Isabelle

    2017-11-10

    The 'trickle-down effect', or how major sports events have a positive impact on sports participation, has been the subject of many studies, but none produced conclusive results. We took a different approach and rather than look at sports participation, we used injuries as a proxy and see if injuries increased, or remained the same, after the International Federation of Association Football World Cup. Using a retrospective cohort design, we looked at the injuries suffered by males and females (13-16 years old) while playing team sports in Montreal, that occurred in May to July, from 1999 to 2014. Information reported by the Canadian Hospitals Injury Reporting Prevention Program (CHIRPP) was limited to the two CHIRPP centres in Montreal: the Montreal Children's Hospital and Hopital Sainte-Justine. In females, no significant trends were noticed. In males who played non-organised soccer, the percent changes between FIFA World Cup (WC) (June) and pre-FIFA WC (May) was always highest during FIFA WC years: 17.2% more injuries in years when FIFA WC was held compared to 1.3% less injuries during non-FIFA WC years. In non-organised soccer, male players suffered less strains/sprains (11.9% vs. 30.1%; P = 0.015), suffered more severe injuries (59.7% vs. 43.1%; P = 0.049) and more of their injuries were the results of direct contact with another player (26.8% vs. 13.3%; P = 0.028) during FIFA WC. FIFA WC seems to have an impact on the injuries of teenage boys when playing non-organised soccer. The impact was short-lived, only lasting during the FIFA WC event. © 2017 Paediatrics and Child Health Division (The Royal Australasian College of Physicians).

  11. [Factors associated with dental consultation in children in Talca (Chile) and in Chilean immigrants in Montreal (Canada)].

    Science.gov (United States)

    Núñez, Loreto; Icaza, Gloria; Contreras, Violeta; Correa, Gloria; Canales, Tatiana; Mejía, Gloria; Oxman-Martínez, Jacqueline; Moreau, Jacques

    2013-01-01

    To identify the factors that influence the use of dental services in 4-7-year-olds and in 10-13-year-olds resident in the cities of Talca (Chile) and Montreal (Canada). A nonprobabilistic cross-sectional study was carried out in 147 boys and girls in Talca and in 94 boys and girls in Montreal between 2009 and 2011. Sociodemographic variables were recorded in parents and children, including age and sex. Data were also gathered on parental education, family composition, and proximity to health centers within neighborhoods. The data were analyzed with Fisher's exact test and the robust Cox regression model (with constant time) with a significance level of 0,05. In Talca, parental education was significantly associated with dental care visits at least twice a year. The children of parents with university education were 2.20 times more likely to consult a dentist (95% CI: 1.30-3.73). Children whose parents perceived their children's health positively were 53% (OR = 0,47; 95% CI: 0,28-0,77) less likely to consult a dentist. In Montreal, the children of parents with university education were 2.10 times more likely to consult a dentist (95%CI: 1.17-3.76), while older children (10-13 years) were 2.11 (95% CI: 1.15-3.88) times more likely to consult a dentist. In both cities, parental education level was associated with the use of dental services. Copyright © 2012 SESPAS. Published by Elsevier Espana. All rights reserved.

  12. Life story chapters, specific memories and the reminiscence bump

    DEFF Research Database (Denmark)

    Thomsen, Dorthe Kirkegaard; Pillemer, David B.; Ivcevic, Zorana

    2011-01-01

    are over-represented at the beginning of chapters. Potential connections between chapters and the cultural life script are also examined. Adult participants first divided their life story into chapters and identified their most positive and most negative chapter. They then recalled a specific memory from......Theories of autobiographical memory posit that extended time periods (here termed chapters) and memories are organised hierarchically. If chapters organise memories and guide their recall, then chapters and memories should show similar temporal distributions over the life course. Previous research...... and that the cultural life script contributes to the search process....

  13. Office-Based Screening for Dementia in Parkinson Disease: The Montreal Parkinson Risk of Dementia Scale in 4 Longitudinal Cohorts.

    Science.gov (United States)

    Dawson, Benjamin K; Fereshtehnejad, Seyed-Mohammad; Anang, Julius B M; Nomura, Takashi; Rios-Romenets, Silvia; Nakashima, Kenji; Gagnon, Jean-François; Postuma, Ronald B

    2018-03-26

    Parkinson disease dementia dramatically increases mortality rates, patient expenditures, hospitalization risk, and caregiver burden. Currently, predicting Parkinson disease dementia risk is difficult, particularly in an office-based setting, without extensive biomarker testing. To appraise the predictive validity of the Montreal Parkinson Risk of Dementia Scale, an office-based screening tool consisting of 8 items that are simply assessed. This multicenter study (Montreal, Canada; Tottori, Japan; and Parkinson Progression Markers Initiative sites) used 4 diverse Parkinson disease cohorts with a prospective 4.4-year follow-up. A total of 717 patients with Parkinson disease were recruited between May 2005 and June 2016. Of these, 607 were dementia-free at baseline and followed-up for 1 year or more and so were included. The association of individual baseline scale variables with eventual dementia risk was calculated. Participants were then randomly split into cohorts to investigate weighting and determine the scale's optimal cutoff point. Receiver operating characteristic curves were calculated and correlations with selected biomarkers were investigated. Dementia, as defined by Movement Disorder Society level I criteria. Of the 607 patients (mean [SD] age, 63.4 [10.1]; 376 men [62%]), 70 (11.5%) converted to dementia. All 8 items of the Montreal Parkinson Risk of Dementia Scale independently predicted dementia development at the 5% significance level. The annual conversion rate to dementia in the high-risk group (score, >5) was 14.9% compared with 5.8% in the intermediate group (score, 4-5) and 0.6% in the low-risk group (score, 0-3). The weighting procedure conferred no significant advantage. Overall predictive validity by the area under the receiver operating characteristic curve was 0.877 (95% CI, 0.829-0.924) across all cohorts. A cutoff of 4 or greater yielded a sensitivity of 77.1% (95% CI, 65.6-86.3) and a specificity of 87.2% (95% CI, 84.1-89.9), with a

  14. Use of alumni and employer surveys for internal quality assurance of the DVM program at the University of Montreal.

    Science.gov (United States)

    Doucet, Michèle Y; Vrins, André

    2010-01-01

    Annual alumni and employer surveys, initially designed as outcomes assessment tools, were integrated into a new internal quality assurance strategy to improve the doctor of veterinary medicine program at the University of Montreal's Faculté de Médecine Vétérinaire. Data collected annually from the classes of 2004-2007 indicated that alumni and their employers were generally satisfied with their level of preparation after one year of professional activity. Specific weaknesses were found in non-technical skills such as communication and resource management. These data were used in support of other forms of feedback to guide curricular reform.

  15. A Decontamination Process to Remove Metals and Stabilise Montreal Sewage Sludge

    Directory of Open Access Journals (Sweden)

    G. Mercier

    2002-01-01

    Full Text Available The Montreal Urban Community (MUC treatment plant produces approximately 270 tons of dry sludge daily (tds/day during physicochemical wastewater treatment. The sludges are burned and contribute to the greenhouse effect by producing atmospheric CO2. Moreover, the sludge emanates a nauseating odour during its thermal stabilisation and retains unpleasant odours for the part (25% that is dried and granulated. To solve this particular problem, the treatment plant authorities are currently evaluating an acidic chemical leaching (sulfuric or hydrochloric acid process at a pH between 2 and 3, using an oxidizing agent such as ferric chloride or hydrogen peroxide (METIX-AC technology, patent pending; [20]. They could integrate it to a 70 tds/day granulated sludge production process. Verification of the application of METIX-AC technology was carried out in a pilot plant set up near the sludge production plant of the MUC. The tests showed that METIX-AC technology can be advantageously integrated to the process used at the MUC. The residual copper (274 ± 58 mg/kg and cadmium (5.6 ± 2.9 mg/kg concentrations in the treated sludge meet legislation standards. The results have also shown that odours have been significantly eliminated for the dewatered, decontaminated, and stabilized biosolids (> 97% compared to the non-decontaminated biosolids. A high rate of odour elimination also was obtained for the liquid leached biosolids (> 93%, compared to the untreated liquid biosolids. The fertilising value (N and P is well preserved by the METIX-AC process. Dissolved organic carbon measurements have showed that little organic matter is brought in solution during the treatment. In fact, the average concentration of dissolved organic carbon measured in the treated liquid phase is 966 ± 352 mg/l, whereas it is 1190 ± 325 mg/l in untreated sludge. The treated sludge was first conditioned with an organic polymer and a coagulant aid. It was successfully dewatered with

  16. Evaluation of the implementation of the Montreal At Home/Chez Soi project.

    Science.gov (United States)

    Fleury, Marie-Josée; Grenier, Guy; Vallée, Catherine

    2014-11-28

    Homelessness and mental disorders constitute a major problem in Canada. The purpose of the At Home/Chez Soi pilot project was to house and provide supports to marginalised groups. Policymakers are in a better position to nurture new, complex interventions if they know which key factors hinder or enable their implementation. This paper evaluates the implementation process for the Montreal site of this project. We collected data from 62 individuals, through individual interviews, focus groups, questionnaires, observations and documentation. The implementation process was analysed using a conceptual framework with five constructs: Intervention Characteristics (IC), Context of Implementation (CI), Implementation Process (IP), Organizational Characteristics (OC) and Strategies of Implementation (SI). The most serious obstacle to the project came from the CI construct, i.e., lack of support from provincial authorities and key local resources in the homelessness field. The second was within the OC construct. The chief hindrances were numerous structures, divergent values among stakeholders, frequent turnover of personnel and team leaders; lacking staff supervision and miscommunication. The third is related to IC: the complex, unyielding nature of the project undermined its chances of success. The greatest challenges from IP were the pressure to perform, along with stress caused by planning, deadlines and tension between teams. Conversely, SI construct conditions (e.g., effective governing structures, comprehensive training initiatives and toolkits) were generally very positive even with problems in power sharing and local leadership. For the four other constructs, the following proved useful: evidence of the project's scope and quality, great needs of services consolidation, generous financing and status as a research pilot project, enthusiasm and commitment toward the project, substantially improved services, and overall user satisfaction. This study demonstrated the

  17. Chapter 2. Adolescents' Attitudes toward the Computer

    Science.gov (United States)

    Russian Education and Society, 2004

    2004-01-01

    This second chapter focuses on an analysis of the aspects that characterize the typical content of students' attitudes toward the world of computers. In this connection, it attempts to determine what is of the greatest interest to students as they deal with the world of computers, which types of programs they use, and which magazines they read…

  18. Chapter 13, Policy options: North America

    Science.gov (United States)

    Jane Barr; James Dobrowolski; John Campbell; Philippe Le Prestre; Lori Lynch; Marc Sydnor; Robert Adler; Jose Etcheverry; Alexander Kenny; Catherine Hallmich; Jim Lazar; Russell M. Meyer; Robin Newmark; Janet Peace; Julie A. Suhr Pierce; Stephen. Yamasaki

    2012-01-01

    As previously indicated, GEO-5 shifts the GEO focus from identifying environmental problems to identifying solutions that governments can then prioritize. This chapter provides examples of a number of policy options and market mechanisms that have shown some success in improving environmental conditions in North America. They are organized by priority environmental...

  19. Chapter Five: Language Learning and Discursive Practice

    Science.gov (United States)

    Young, Richard F.

    2008-01-01

    This chapter is framed by the three questions related to learning in Practice Theory posed by Johannes Wagner (2008): (1) What is learned?; (2) Who is learning?; and (3) Who is participating in the learning? These questions are addressed in two learning theories: Language Socialization and Situated Learning theory. In Language Socialization, the…

  20. Other pospiviroids infecting Solanaceous plants (Book Chapter)

    Science.gov (United States)

    Aside from potato spindle tuber viroid, the genus Pospiviroid contains several agents reported to naturally infect solanaceous crops (e.g. tomato, potato, pepper) or ornamental plants (e.g. Petunia hybrida, Solanum spp., Brugmansia spp.). The present chapter focuses on the following so-called solana...

  1. Transfer of property inter vivos : chapter 7

    NARCIS (Netherlands)

    van Vliet, Lars

    2017-01-01

    This chapter will give an overview of the various transfer systems for movable property and immovable property. It will focus on voluntary transfers based on a legal act between the transferor and transferee. First the difference between the unitary approach and the functional approach to passing of

  2. Denmark - Chapter in Handbook of Global Bioethics

    DEFF Research Database (Denmark)

    Nielsen, Linda; Faber, Berit A.

    2014-01-01

    This chapter about bioethics in Denmark focuses on specific Danish characteristics. These are the early start of a bioethics debate, legislation and bioethics councils; the independence of the councils and the parliamentarians voting on ethical issues; the introduction and extraordinary importance...... of laymen as a part of the bioethical debate and decisions; and the strong focus on debate and educational tools....

  3. Life cycle analysis of biochar [Chapter 3

    Science.gov (United States)

    Richard D. Bergman; Hongmei Gu; Deborah S. Page-Dumroese; Nathaniel M. Anderson

    2017-01-01

    All products, including bioproducts, have an impact on the environment by consuming resources and releasing emissions during their production. Biochar, a bioproduct, has received considerable attention because of its potential to sequester carbon in soil while enhancing productivity, thus aiding sustainable supply chain development. In this chapter, the environmental...

  4. Invasive species in southern Nevada [Chapter 4

    Science.gov (United States)

    Mathew L. Brooks; Steven M. Ostoja; Jeanne C. Chambers

    2013-01-01

    Southern Nevada contains a wide range of topographies, elevations, and climatic zones emblematic of its position at the ecotone between the Mojave Desert, Great Basin, and Colorado Plateau ecoregions. These varied environmental conditions support a high degree of biological diversity (Chapter 1), but they also provide opportunities for a wide range of invasive species...

  5. Adaptation strategies and approaches: Chapter 2

    Science.gov (United States)

    Patricia Butler; Chris Swanston; Maria Janowiak; Linda Parker; Matt St. Pierre; Leslie. Brandt

    2012-01-01

    A wealth of information is available on climate change adaptation, but much of it is very broad and of limited use at the finer spatial scales most relevant to land managers. This chapter contains a "menu" of adaptation actions and provides land managers in northern Wisconsin with a range of options to help forest ecosystems adapt to climate change impacts....

  6. Landscape genomics: A brief perspective [Chapter 9

    Science.gov (United States)

    Michael K. Schwartz; Gordon Luikart; Kevin S. McKelvey; Samuel A. Cushman

    2010-01-01

    Landscape genetics is the amalgamation of population genetics and landscape ecology (see Manel et al. 2003; Storfer et al. 2007). In Chapter 17, we discuss landscape genetics and provide two examples of applications in the area of modeling population connectivity and inferring fragmentation. These examples, like virtually all extant landscape genetic analyses, were...

  7. Chapter 9: Questions from CNEN specific exams

    International Nuclear Information System (INIS)

    2018-01-01

    The following are real questions from CNEN specific exams for obtaining the certification of RSO for gamma irradiators. These are questions that require essay answers, that are interpretative ones and therefore that may accept more than one interpretation, therefore more than one answer. For this reason, suggestions of answers will be presented in the second part of this chapter

  8. Chapter 3: Status and trends of vegetation

    Science.gov (United States)

    James M. Guldin; Frank R. Thompson; Lynda L. Richards; Kyra C. Harper

    1999-01-01

    This chapter provides information about the vegetation cover of the Assessment area. The types and areal extent of vegetation in the Highlands are of interest for many reasons. Vegetation cover largely determines the availability of habitat for terrestrial animals, plants, and other organisms. Vegetation cover strongly influences what uses {e.g., timber, forage,...

  9. Chapter 6: Accidents; Capitulo 6: Acidentes

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2014-06-01

    The chapter 6 talks about the accidents with radiators all over the world, specifically, the Stimos, in Italy, 1975, San Salvador, in El Salvador, 1989, Soreq, in Israel, 1990, Nesvizh, in Byelorussian, 1991, in Illinois, US, 1965, in Maryland, US, 1991, Hanoi, Vietnam, 1992, Fleurus, in Belgium, 2006. Comments on the accidents and mainly the learned lessons.

  10. Science, practice, and place [Chapter 2

    Science.gov (United States)

    Daniel R. Williams

    2013-01-01

    Place-oriented inquiry and practice are proposed as keys to overcoming the persistent gap between science and practice. This chapter begins by describing some of the reasons science fails to simplify conservation practice, highlighting the challenges associated with the social and ecological sciences of multi-scaled complexity. Place concepts help scientists and...

  11. Acquisition and Processing of High Resolution Hyperspectral Imageries for the 3d Mapping of Urban Heat Islands and Microparticles of Montreal

    Science.gov (United States)

    Mongeau, R.; Baudouin, Y.; Cavayas, F.

    2017-10-01

    Ville de Montreal wanted to develop a system to identify heat islands and microparticles at the urban scale and to study their formation. UQAM and UdeM universities have joined their expertise under the framework "Observatoire Spatial Urbain" to create a representative geospatial database of thermal and atmospheric parameters collected during the summer months. They innovated in the development of a methodology for processing high resolution hyperspectral images (1-2 m). In partnership with Ville de Montreal, they integrated 3D geospatial data (topography, transportation and meteorology) in the process. The 3D mapping of intraurban heat islands as well as air micro-particles makes it possible, initially, to identify the problematic situations for future civil protection interventions during extreme heat. Moreover, it will be used as a reference for the Ville de Montreal to establish a strategy for public domain tree planting and in the analysis of urban development projects.

  12. Overview of Current Labelling Methods. Chapter 2

    International Nuclear Information System (INIS)

    Alberto, R.

    2009-01-01

    The conjugation of 99m Tc complexes or complex fragments to targeting vectors is the core science of labelling chemistry. The first sections of the chapter outline the non-chemical constraints to be considered for successful biomolecule labelling and for a chance of becoming introduced to the market. Without taking these constraints into account, even the best radiopharmaceutical will not gain access to the market. Labelling methods, which either fulfil these constraints completely or, at least, to a significant extent, will then be emphasized. Besides the old cores, such as [Tc=O] 3+ , the novel cores [Tc] 3+ , [Tc≡N] 2+ and [Tc(CO) 3 ] + as well as the intensive research based on these cores are discussed in detail. Recent examples towards novel 99m Tc based radiopharmaceuticals are described. Based on the current methods for the labelling of biomolecules, the objective of the chapter is to guide towards potential novel approaches in radiopharmaceutical chemistry. (author)

  13. Vaccination against bacterial kidney disease: Chapter 22

    Science.gov (United States)

    Elliott, Diane G.; Wiens, Gregory D.; Hammell, K. Larry; Rhodes, Linda D.; Edited by Gudding, Roar; Lillehaug, Atle; Evensen, Øystein

    2014-01-01

    Bacterial kidney disease (BKD) of salmonid fishes, caused by Renibacterium salmoninarum, has been recognized as a serious disease in salmonid fishes since the 1930s. This chapter discusses the occurrence and significance, etiology, and pathogenesis of BKD. It then describes the different vaccination procedures and the effects and side-effects of vaccination. Despite years of research, however, only a single vaccine has been licensed for prevention of BKD, and has demonstrated variable efficacy. Therefore, in addition to a presentation of the current status of BKD vaccination, a discussion of potential future directions for BKD vaccine development is included in the chapter. This discussion is focused on the unique characteristics of R. salmoninarum and its biology, as well as aspects of the salmonid immune system that might be explored specifically to develop more effective vaccines for BKD prevention.

  14. GOSPEL OF ST. JOHN, CHAPTER 21

    Directory of Open Access Journals (Sweden)

    A. PROKOPTCHUK

    2006-01-01

    Full Text Available The purpose of this report is to show that chapter 21 of Jn is inseparably linked withall previous material of the fourth Gospel. These links are more than sufficient. The sup-position that this chapter was not in the original text has become long established, how-ever there has not existed any objective evidence for this fact. Critique has always had away of raising itself above the Scripture. In the author’s opinion a researcher’s role isrelated to that of St. John. Each of us becomes an eyewitness of the things seen and per-ceived. We should not rise above the text, but keep at the same level with it in order tohave a deep insight into author’s enigma, Christ’s enigma and get it across to our hear-ers

  15. Analysis of Chinese emissions trends of major halocarbons in monitoring the impacts of the Montreal Protocol

    Science.gov (United States)

    Li, S.; Park, S.; Park, M.; Kim, J.; Muhle, J.; Fang, X.; Stohl, A.; Weiss, R. F.; Kim, K.

    2013-12-01

    nationwide effort for the Clean Development Mechanism project benefit of the Kyoto protocol. Emission rates of the halocarbons determined from the empirical emission strengths will certainly vary according to emission trend of our reference species, HCFC-22 in China from 2008 and 2012. Annual and average of HCFC-22 emissions from 2008 to 2012 will be calculated with an inverse method based on FLEXPART transport model. More detailed discussion on the emission rate estimation and its related caveats will be made in the presentation, but overall our analysis highlights the significance of long-term continuous monitoring for CFCs, HCFCs and HFCs in China to investigate impacts of Montreal Protocol regulations.

  16. Structural diversity in gallium(III) complexes of the tripodal triarsine MeC(CH2AsMe2)3.

    Science.gov (United States)

    Cheng, Fei; Hector, Andrew L; Levason, William; Reid, Gillian; Webster, Michael; Zhang, Wenjian

    2007-06-07

    The preparation and crystal structures of the first examples of gallium halide complexes with the tripodal arsine, MeC(CH(2)AsMe(2))3, reveal three distinctly different coordination modes for the ligand; the neutral [{micro(3)-MeC(CH(2)AsMe(2))3-kappaAs:kappaAs':kappaAs''}(GaI(3))3] with the triarsine coordinating to three GaI(3) units, [{Me(2)AsCH(2)C(Me)(CH(2)AsMe(2))2-kappa(2)AsAs'}GaCl(2)][GaCl(4)] involving bidentate chelation to a GaCl2+ cationic unit with the third As donor atom uncoordinated, and [{MeC(CH(2)AsMe(2))3-kappaAs:kappa(2)As'As''}(GaCl3)(GaCl2)][GaCl4] in which the triarsine forms a bidentate chelate to the GaCl2+ unit and the third As donor atom binds to a further GaCl3 unit.

  17. Dynamic experiments with high bisphenol-A concentrations modelled with an ASM model extended to include a separate XOC degrading microorganism

    DEFF Research Database (Denmark)

    Lindblom, Erik Ulfson; Press-Kristensen, Kåre; Vanrolleghem, P.A.

    2009-01-01

    with the endocrine disrupting XOC bisphenol-A (BPA) in an activated sludge process with real wastewater were used to hypothesize an ASM-based process model including aerobic growth of a specific BPA-degrading microorganism and sorption of BPA to sludge. A parameter estimation method was developed, which...

  18. Comportamiento de variables clínico-epidemiológicas en pacientes asmáticos. Consultorio Médico de Familia 14, Puerto Padre

    Directory of Open Access Journals (Sweden)

    José Ramón Martínez Pérez

    2015-12-01

    Full Text Available Se realizó un estudio descriptivo de corte transversal en 40 pacientes asmáticos de todas las edades, pertenecientes al Consultorio 14 del área de salud de Puerto Padre, provincia de Las Tunas, durante los meses de enero a junio de 2008; con el objetivo de determinar el comportamiento de variables clínico-epidemiológicas en dichos pacientes. Para cumplimentar los objetivos se diseñó una encuesta que recogió las variables de interés. El análisis se hizo a través del sistema Statistix, permitiendo  obtener  la distribución de frecuencia y los porcientos. El test de Chi-Cuadrado se empleó en la comparación de variables cualitativas. Los resultados fueron descritos, interpretados y comparados con otros estudios. Se concluye que los pacientes grado I según Kraeppelin son los mas representados en nuestra población de pacientes asmáticos;  los broncodilatadores son los medicamentos mas utilizados por la población asmática estudiada; el incumplimiento del tratamiento medicamentoso no se relacionó con la severidad de la enfermedad en la población estudiada;  las malas condiciones de la vivienda y  el tabaquismo influyeron de forma negativa en la evolución del paciente asmático.

  19. Comparisons of ANS, ASME, AWS, and NFPA standards cited in the NRC standard review plan, NUREG-0800, and related documents

    Energy Technology Data Exchange (ETDEWEB)

    Ankrum, A.R.; Bohlander, K.L.; Gilbert, E.R.; Spiesman, J.B. [Pacific Northwest Lab., Richland, WA (United States)

    1995-11-01

    This report provides the results of comparisons of the cited and latest versions of ANS, ASME, AWS and NFPA standards cited in the NRC Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants (NUREG 0800) and related documents. The comparisons were performed by Battelle Pacific Northwest Laboratories in support of the NRC`s Standard Review Plan Update and Development Program. Significant changes to the standards, from the cited version to the latest version, are described and discussed in a tabular format for each standard. Recommendations for updating each citation in the Standard Review Plan are presented. Technical considerations and suggested changes are included for related regulatory documents (i.e., Regulatory Guides and the Code of Federal Regulations) citing the standard. The results and recommendations presented in this document have not been subjected to NRC staff review.

  20. Optimization of the Production of Sludge in an Activated Sludge System Through the Calibration of the ASM1 Model

    Directory of Open Access Journals (Sweden)

    Espinosa-Rodríguez M.A

    2015-01-01

    Full Text Available Recently several protocols have been proposed for the calibration the ASM1 model and each one of them emphasizes obtaining a good adjustment in the production of sludge. Precisely here is where the discrepancies are evaluated and adjustments made to data, through a mass balance. The objective of this work was to conduct first a balance of flows in the wastewater treatment plant "Dulces Nombres" in Monterrey, Nuevo Leon, Mexico, and then adjust them until closing properly the mass balance for the total phosphorus, total suspended solids, and inorganic suspended solids (ISS. On might say that to calibrate the biological model was important to determine reliably the flow of sludge (QWAS since on it depends the cell retention mean time (θC in the reactor; this was accomplished successfully through the balance of the ISS and using of GPS-X software for the simulation of scenarios of optimization.

  1. Comparisons of ANS, ASME, AWS, and NFPA standards cited in the NRC standard review plan, NUREG-0800, and related documents

    International Nuclear Information System (INIS)

    Ankrum, A.R.; Bohlander, K.L.; Gilbert, E.R.; Spiesman, J.B.

    1995-11-01

    This report provides the results of comparisons of the cited and latest versions of ANS, ASME, AWS and NFPA standards cited in the NRC Standard Review Plan for the Review of Safety Analysis Reports for Nuclear Power Plants (NUREG 0800) and related documents. The comparisons were performed by Battelle Pacific Northwest Laboratories in support of the NRC's Standard Review Plan Update and Development Program. Significant changes to the standards, from the cited version to the latest version, are described and discussed in a tabular format for each standard. Recommendations for updating each citation in the Standard Review Plan are presented. Technical considerations and suggested changes are included for related regulatory documents (i.e., Regulatory Guides and the Code of Federal Regulations) citing the standard. The results and recommendations presented in this document have not been subjected to NRC staff review

  2. Aeração nasal em crianças asmáticas Nasal ventilation in asthmatics children

    Directory of Open Access Journals (Sweden)

    Daniele Andrade da Cunha

    2011-10-01

    Full Text Available OBJETIVO: identificar a presença de sinais de alterações na expiração de crianças asmáticas. MÉTODO: este estudo foi realizado com 30 crianças com idades entre 6 e 10 anos de ambos os sexos com diagnóstico clínico de asma confirmado pelo prontuário médico e 30 crianças não asmáticas também de ambos os sexos na mesma faixa etária. Foi avaliada a aeração nasal com o espelho milimetrado de Altmann, sendo mensurado o escape de ar nasal objetivando a verificação da saída uni ou bilateral do ar e a relação de simetria entre a narina direita e a esquerda. As imagens foram importadas para o computador por meio do scanner HP da série Scanjet 2400. A análise foi realizada no software Scion Image for Windows (Alpha 4.0.3.2. Para análise das variáveis quantitativas entre grupos foi aplicado o teste t-student e para a análise intragrupos foi aplicado o teste t-Student pareado.Todas as conclusões foram tomadas ao nível de significância de 5%, sendo usados o Excel 2000 e o SPSS v8.0, para as análises. RESULTADOS: não foram encontradas diferenças estatisticamente significantes entre as crianças asmáticas e não-ásmáticas, acerca das mensurações quanto à área total e quanto às áreas das narinas direita e esquerda. CONCLUSÃO: não foi identificada a presença de sinais de alterações na expiração de crianças asmáticas, desta forma, faz-se necessário um estudo mais específico das funções nasal e pulmonar.PURPOSE: to identify the symptoms of changes in the exhalation of asthmatic children. METHOD: this study was conducted with 30 children from 6 to 10 year-old, of both genders and with asthma clinical diagnosis confirmed by medical records and 30 non-asthmatic children from 6 to 10 year-old, of both genders, and with same age. We evaluated the nasal ventilation with Altmann millimeter nasal mirror measuring the nasal air escape in order to check their unilateral or bilateral air output and the relation of

  3. IRIG 106 Chapter 10 Programmers Handbook

    Science.gov (United States)

    2016-08-16

    IRIG 106 Chapter 10 Programmers’ Handbook RCC 123-16 August 2016 xii PS program stream RCC Range Commanders Council RFC Request for Comment RIU...Force (IETF) has published Request For Comment ( RFC ) 32709 defining the Internet Small Computer Systems Interface (iSCSI) protocol for transporting...NMEA National Marine Electronics Association ORB operation request block PCM pulse code modulation PDU protocol data unit PHY Physical Layer

  4. Haramekhala - tantra (the first chapter on medicine).

    Science.gov (United States)

    Sharma, P V

    1986-01-01

    This translation of Haramekhala - tantra of the author is based on Banaras Hindu University manuscript which seems to be a novel one. The manuscript runs into 133 stanzas in all in the form of dialogue between lord Siva and goddess Parvati. This is only the first chapter (of the great work) dealing with medicine. From stanza 109 onwards some magic spells are described and as such those have not been included in this translation.

  5. Gaia DR1 documentation Chapter 3: Astrometry

    Science.gov (United States)

    Hobbs, D.; Lindegren, L.; Bastian, U.; Klioner, S.; Hernandez, J.; Lammers, U.; Bombrun, A.; Mignard, F.; Altmann, M.; Andrei, A.; Davidson, M.; de Bruijne, J. H. J.

    2017-12-01

    This chapter presents the models and processing steps used for Gaia's core solution, namely, the Astrometric Global Iterative Solution (AGIS). The inputs to this solution rely heavily on the basic observables (or astrometric elementaries) which have been pre-processed and discussed in Chapter 2, the results of which have been published in Fabricius et al. (2016). The models consist of reference systems and time scales; assumed linear stellar motion and relativistic light deflection; in addition to fundamental constants and the transformation of coordinate systems. Higher level inputs such as: planetary and solar system ephemeris; Gaia tracking and orbit information; initial quasar catalogues and BAM data are all needed for the processing described here. The astrometric calibration models are outlined followed by the details processing steps which give AGIS its name. The final Section 3.5 represents a basic quality assessment and validation of the scientific results which has also been published in detail in Lindegren et al. (2016). However, the validation of the science products was not restricted to just this, a more independent catalogue consolidation and validation of the science results for Gaia DR1 was also performed and are documented in Chapter 7 and have been published in Arenou et al. (2017).

  6. Solid Lubrication Fundamentals and Applications. Chapter 6

    Science.gov (United States)

    Miyoshi, Kazuhisa

    2000-01-01

    This chapter focuses attention on the friction and wear properties of selected solid lubricating films to aid users in choosing the best lubricant, deposition conditions, and operational variables. For simplicity, discussion of the tribological properties of concern is separated into two parts. The first part of the chapter discusses the different solid lubricating films selected for study including commercially developed solid film lubricants: (1) bonded molybdenum disulfide (MoS2), (2) magnetron-sputtered MoS2, (3) ion-plated silver, (4) ion-plated lead, (5) magnetron-sputtered diamondlike carbon (MS DLC), and (6) plasma-assisted, chemical-vapor-deposited diamondlike carbon (PACVD DEC) films. Marked differences in the friction and wear properties of the different films resulted from the different environmental conditions (ultrahigh vacuum, humid air, and dry nitrogen) and the solid film lubricant materials. The second part of the chapter discusses the physical and chemical characteristics, friction behavior, and endurance life of the magnetron-sputtered MoS2 films. The role of interface species and the effects of applied load, film thickness, oxygen pressure, environment, and temperature on the friction and wear properties are considered.

  7. Pengaruh pH, Kecepatan Putar dan Asam Asetat terhadap Karakteristik CO2 Corrosion Baja ASME SA516 grade 70

    Directory of Open Access Journals (Sweden)

    Faris Adham

    2017-01-01

    Full Text Available Fenomena korosi merupakan sesuatu yang pasti terjadi pada setiap logam. Laju korosi dari suatu material dipengaruhi oleh beberapa faktor diantaranya yaitu nilai pH lingkungan dan karakteristik aliran fluida yang kontak langsung dengan logam. Pada oil and gas industry, baja ASME SA 516 grade 70 sering digunakan sebagai material flowline dan banyak terjadi CO2 Corrosion. Penelitian ini bertujuan untuk melakukan studi laju korosi material baja ASME SA 516 grade 70 yang mengandung CO2. Penelitian dilakukan dengan metoda weight loss menggunakan alat Rotating Cylinder Electrode (RCE selama 10 hari dan metode Polarization selama 1 jam. Selain itu digunakan pula XRD dan SEM guna mendukung data-data analisa. Pada penelitian ini digunakan media elektrolit NaCl 3,5% dengan kandungan CH3COOH sebesar 0 ppm dan 1500 ppm dengan variasi kecepatan putaran yaitu 0 RPM, 150 RPM, 300 RPM, dan 450 RPM pada pH 5 dan 6. Pada pengujian polarization, didapatkan hasil laju korosi tertinggi sebesar 9.9323 mm/y pada larutan CH3COOH 1500 ppm pH 5 dan kecepatan putar 450 RPM, sedangkan data dari pengujian weight loss sebesar 4.8795 mm/y. Hasil pengamatan SEM menunjukkan adanya perbedaan morfologi pada permukaan spesimen karena pengaruh kecepatan putaran. Kecepatan putaran mengakibatkan tergerusnya produk korosi oleh aliran. Pada pengujian XRD dengan menggunakan spesimen pH 5 dengan kandungan 0 ppm dan 1500 ppm 0 RPM ditemukan FeCO3, Fe(OH3 dan senyawa FeOOH sebagai produk korosi.

  8. Regulatory Safety Issues in the Structural Design Criteria of ASME Section III Subsection NH and for Very High Temperatures for VHTR and GEN IV

    International Nuclear Information System (INIS)

    O'Donnell, William J.; Griffin, Donald S.

    2007-01-01

    The objective of this task is to identify issues relevant to ASME Section III, Subsection NH [1], and related Code Cases that must be resolved for licensing purposes for VHTGRs (Very High Temperature Gas Reactor concepts such as those of PBMR, Areva, and GA); and to identify the material models, design criteria, and analysis methods that need to be added to the ASME Code to cover the unresolved safety issues. Subsection NH was originally developed to provide structural design criteria and limits for elevated-temperature design of Liquid Metal Fast Breeder Reactor (LMFBR) systems and some gas-cooled systems. The U.S. Nuclear Regulatory Commission (NRC) and its Advisory Committee for Reactor Safeguards (ACRS) reviewed the design limits and procedures in the process of reviewing the Clinch River Breeder Reactor (CRBR) for a construction permit in the late 1970s and early 1980s, and identified issues that needed resolution. In the years since then, the NRC and various contractors have evaluated the applicability of the ASME Code and Code Cases to high-temperature reactor designs such as the VHTGRs, and identified issues that need to be resolved to provide a regulatory basis for licensing. This Report describes: (1) NRC and ACRS safety concerns raised during the licensing process of CRBR , (2) how some of these issues are addressed by the current Subsection NH of the ASME Code; and (3) the material models, design criteria, and analysis methods that need to be added to the ASME Code and Code Cases to cover unresolved regulatory issues for very high temperature service.

  9. Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect.

    Science.gov (United States)

    Patel, Brijeshkumar S; Kugel, Michael J; Baehring, Gina; Ammit, Alaina J

    2017-08-01

    The xanthine doxofylline has been examined in clinical trials and shown to have efficacy and greater tolerability than theophylline in asthma and chronic obstructive pulmonary disease. The 'novofylline' doxofylline has demonstrated bronchodilatory and anti-inflammatory actions in in vivo and ex vivo experimental models of respiratory disease. However, there are limited studies in vitro. We address this herein and examine whether doxofylline has anti-inflammatory impact on primary cultures of airway smooth muscle (ASM) cells. We conduct a series of investigations comparing and contrasting doxofylline with the archetypal xanthine, theophylline, and the specific phosphodiesterase (PDE) 4 inhibitor, cilomilast. We confirm that the xanthine drugs do not have action as PDE inhibitors in ASM cells. Unlike cilomilast, doxofylline (and theophylline) do not increase cAMP production in ASM cells induced by long-acting β 2 -agonist formoterol. Similar to theophylline, and consistent with the lack of cAMP potentiation, doxofylline does not augment formoterol-induced upregulation of the anti-inflammatory protein mitogen-activated protein kinase phosphatase 1 (MKP-1). However, when we examine the effect of doxofylline on secretion of the interleukin 8 from ASM cells stimulated by tumour necrosis factor (an in vitro surrogate measure of inflammation), there was no repression of inflammation. This is in contrast to the anti-inflammatory impact exerted by theophylline and cilomilast in confirmatory experiments. In summary, our study is the first to examine the effect of doxofylline on ASM cells in vitro and highlights some distinct differences between two key members of xanthine drug family, doxofylline and theophylline. Copyright © 2017 Elsevier Ltd. All rights reserved.

  10. TRAIL death receptor 4 signaling via lysosome fusion and membrane raft clustering in coronary arterial endothelial cells: evidence from ASM knockout mice.

    Science.gov (United States)

    Li, Xiang; Han, Wei-Qing; Boini, Krishna M; Xia, Min; Zhang, Yang; Li, Pin-Lan

    2013-01-01

    Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) and its receptor, death receptor 4 (DR4), have been implicated in the development of endothelial dysfunction and atherosclerosis. However, the signaling mechanism mediating DR4 activation leading to endothelial injury remains unclear. We recently demonstrated that ceramide production via hydrolysis of membrane sphingomyelin by acid sphingomyelinase (ASM) results in membrane raft (MR) clustering and the formation of important redox signaling platforms, which play a crucial role in amplifying redox signaling in endothelial cells leading to endothelial dysfunction. The present study aims to investigate whether TRAIL triggers MR clustering via lysosome fusion and ASM activation, thereby conducting transmembrane redox signaling and changing endothelial function. Using confocal microscopy, we found that TRAIL induced MR clustering and co-localized with DR4 in coronary arterial endothelial cells (CAECs) isolated from wild-type (Smpd1 (+/+)) mice. Furthermore, TRAIL triggered ASM translocation, ceramide production, and NADPH oxidase aggregation in MR clusters in Smpd1 ( +/+ ) CAECs, whereas these observations were not found in Smpd1 (-/-) CAECs. Moreover, ASM deficiency reduced TRAIL-induced O(2) (-[Symbol: see text]) production in CAECs and abolished TRAIL-induced impairment on endothelium-dependent vasodilation in small resistance arteries. By measuring fluorescence resonance energy transfer, we found that Lamp-1 (lysosome membrane marker protein) and ganglioside G(M1) (MR marker) were trafficking together in Smpd1 (+/+) CAECs, which was absent in Smpd1 (-/-) CAECs. Consistently, fluorescence imaging of living cells with specific lysosome probes demonstrated that TRAIL-induced lysosome fusion with membrane was also absent in Smpd1 (-/-) CAECs. Taken together, these results suggest that ASM is essential for TRAIL-induced lysosomal trafficking, membrane fusion and formation of MR redox signaling platforms

  11. Assessing the Multiple Benefits of Clean Energy Chapter 1: Introduction

    Science.gov (United States)

    Chapter 1 of “Assessing the Multiple Benefits of Clean Energy” provides an introduction to the document. /meta name=DC.title content=Assessing the Multiple Benefits of Clean Energy Chapter 1: Introduction

  12. The Domestic Foodscapes of Young Low-Income Women in Montreal: Cooking Practices in the Context of an Increasingly Processed Food Supply

    Science.gov (United States)

    Engler-Stringer, Rachel

    2010-01-01

    Over the course of the past century, the quantity of prepackaged, pre-prepared foods available in the North American context has increased dramatically. This study examines the shifts in food practices that are taking place through an exploration of the day-to-day cooking practices of a group of young, low-income women in Montreal and considers…

  13. Risk of lung cancer associated with six types of chlorinated solvents: results from two case-control studies in Montreal, Canada

    Science.gov (United States)

    Methods: Two case-control studies of occupation and lung cancer were conducted in Montreal, including 2,016 cases and 2,001 population controls. Occupational exposure to a host of agents was evaluated using a combination of subject-reported job history and expert assessment. We e...

  14. Using Kolb's Experiential Learning Cycle in Chapter Presentations

    Science.gov (United States)

    Stokes-Eley, Stephanie

    2007-01-01

    Student-led chapter presentations provide an excellent opportunity for instructors to evaluate a student's comprehension of the assigned chapter, as well as the student's ability to present and convey information in a public forum. Although several instructors realize the benefits of requiring students to complete chapter presentations either as…

  15. Association Between Montreal Cognitive Assessment Scores and Measures of Functional Mobility in Lower Extremity Amputees After Inpatient Rehabilitation.

    Science.gov (United States)

    Frengopoulos, Courtney; Burley, Joshua; Viana, Ricardo; Payne, Michael W; Hunter, Susan W

    2017-03-01

    To determine whether scores on a cognitive measure are associated with walking endurance and functional mobility of individuals with transfemoral or transtibial amputations at discharge from inpatient prosthetic rehabilitation. Retrospective cohort study. Rehabilitation hospital. Consecutive admissions (N=176; mean age ± SD, 64.27±13.23y) with transfemoral or transtibial amputation that had data at admission and discharge from an inpatient prosthetic rehabilitation program. Not applicable. Cognitive status was assessed using the Montreal Cognitive Assessment (MoCA). The L Test and the 2-minute walk test (2MWT) were used to estimate functional mobility and walking endurance. The mean ± SD MoCA score was 24.05±4.09 (range, 6-30), and 56.3% of patients had scores rehabilitation on the basis of cognitive impairment alone. Copyright © 2016 American Congress of Rehabilitation Medicine. Published by Elsevier Inc. All rights reserved.

  16. Significant Weakening of Brewer-Dobson Circulation Trends Over the 21st Century as a Consequence of the Montreal Protocol

    Science.gov (United States)

    Polvani, Lorenzo M.; Abalos, Marta; Garcia, Rolando; Kinnison, Doug; Randel, William J.

    2018-01-01

    It is well established that increasing greenhouse gases, notably CO2, will cause an acceleration of the stratospheric Brewer-Dobson circulation (BDC) by the end of this century. We here present compelling new evidence that ozone depleting substances are also key drivers of BDC trends. We do so by analyzing and contrasting small ensembles of "single-forcing" integrations with a stratosphere resolving atmospheric model with interactive chemistry, coupled to fully interactive ocean, land, and sea ice components. First, confirming previous work, we show that increasing concentrations of ozone depleting substances have contributed a large fraction of the BDC trends in the late twentieth century. Second, we show that the phasing out of ozone depleting substances in coming decades—as a consequence of the Montreal Protocol—will cause a considerable reduction in BDC trends until the ozone hole is completely healed, toward the end of the 21st century.

  17. [Compulsory internship in diagnostic radiology in the 5th year of medicine at the University of Montreal].

    Science.gov (United States)

    Saint-Georges, G; Raymond-Tremblay, D; Danais, S; Dussault, R; Grignon, A; Lafortune, M; Saltiel, J

    1984-01-01

    Problems of methodology, organization, and evaluation confronting the radiology departments of the university hospitals affiliated with the University of Montreal, the medical students, and the University itself in connection with an elective internship in radiology offered in the fifth year of medicine, resulted in the formation of a committee to reorganize the course of study. In this concise article the authors describe this and other measures taken by the University to solve these problems. The committees' main purpose was to restructure the internship which was made compulsory so that future physicians would be prepared to draw on the resources of diagnostic radiology and nuclear medicine. To this end, the committee formulated the objectives, content, evaluation system, and pedagogical methods to be used in those courses. The 25 self-teaching modules, together with the observation and practical interpretation of radiology sessions, proved highly useful in solving the initial problems, and were of particular interest to the students.

  18. Promoting the APS Chapter Program by sharing its history, best practices, and how-to guide for establishing new chapters.

    Science.gov (United States)

    Hopper, Mari K

    2017-03-01

    Early establishment of physiological societies in Oklahoma and Ohio demonstrated the benefits of networking physiologists and paved the way for establishing the APS Chapter Program. Designed to promote the general objectives of the APS, the Chapter Program was officially launched in 1995, with Ohio being the first recognized chapter. There are 13 active chapters regularly engaged in numerous activities designed to advance physiology education and research. In the hopes that others will recognize the important offerings of state chapters and consider organizing one, the aims for this paper are to 1) share a brief history, 2) provide rationale for chapter initiation, and 3) describe the process involved in establishing a chapter. In light of current changes in American Medical Association and Liaison Committee on Medical Education guidelines, the present time may be critical in promoting chapters, as they play a vital role in sustaining recognition and support for the discipline. Copyright © 2017 the American Physiological Society.

  19. Solid Lubrication Fundamentals and Applications. Chapter 2

    Science.gov (United States)

    Miyoshi, Kazuhisa

    1998-01-01

    This chapter describes powerful analytical techniques capable of sampling tribological surfaces and solid-film lubricants. Some of these techniques may also be used to determine the locus of failure in a bonded structure or coated substrate; such information is important when seeking improved adhesion between a solid-film lubricant and a substrate and when seeking improved performance and long life expectancy of solid lubricants. Many examples are given here and through-out the book on the nature and character of solid surfaces and their significance in lubrication, friction, and wear. The analytical techniques used include the late spectroscopic methods.

  20. Chapter three: methodology of exposure modeling

    CSIR Research Space (South Africa)

    Moschandreas, DJ

    2002-12-01

    Full Text Available not be the most important pathway of exposure for all pollutants, it is considered the one of major concern for exposure to PM. Related concepts, such as dose, will not be addressed in this chapter. The National Academy of Sciences suggests the fol- lowing model... over time. Other exposure expressions are used to estimate exposures to pollutants in the in- gestion and dermal absorption pathways. Major variables of concern in the estimation of ex- posure, Eq. (2), are the concentration of PM and its constituents...

  1. Space Applications of Mass Spectrometry. Chapter 31

    Science.gov (United States)

    Hoffman, John H.; Griffin, Timothy P.; Limero, Thomas; Arkin, C. Richard

    2010-01-01

    Mass spectrometers have been involved in essentially all aspects of space exploration. This chapter outlines some of these many uses. Mass spectrometers have not only helped to expand our knowledge and understanding of the world and solar system around us, they have helped to put man safely in space and expand our frontier. Mass spectrometry continues to prove to be a very reliable, robust, and flexible analytical instrument, ensuring that its use will continue to help aid our investigation of the universe and this small planet that we call home.

  2. Utilização de Ecolife® e Acibenzolar-s-metil (ASM no controle da antracnose da banana em pós-colheita Use of Ecolife® and Acibenzolar-S-metil (ASM on the control of antracnosis in banana post-harvest

    Directory of Open Access Journals (Sweden)

    Luciano Marinho Furtado

    2010-09-01

    Full Text Available O objetivo deste trabalho foi avaliar a ação dos produtos ASM e Ecolife no controle da antracnose pós-colheita em frutos de banana. Frutos sadios de banana, variedades maçã, prata, pacovan e cacau , em fase intermediária de maturação, foram imersos previamente em soluções de ASM e Ecolife e inoculados com Colletotrichum musae. Utilizou-se o delineamento inteiramente casualizado, em esquema fatorial com quatro repetições. Os resultados apresentados demonstraram a eficácia dos produtos nas concentrações de 5 ml/ L (Ecolife e 0,50g/ L (ASM no controle da antracnose nas variedades analisa das. A variedade cacau apresentou menor lesão quando tratada com o Ecolife (5,79 mm. Com relação ao efeito do ASM, a bana na prata demonstrou um melhor resultado, com tamanho médio de lesão de 5,62 mm. Com o decorrer do processo de maturação dos frutos houve um decréscimo na severidade da doença nas quatro variedades estudadas, exceto no tratamento testemunha, que continuou apresentando aumento no tamanho das lesões nos frutos e atingir a polpa ao final da maturação.The aim of this work was to evaluate the effects of ASM and Ecolife on the control of post-harvest antracnosis in banana. Banana fruits of Maçã, Prata, Pacovan and Figo varieties, at intermediate stage of maturation, were immersed in solutions of ASM and Ecolife and inoculated with Colletotrichum musae A completely randomized design was used, at a factorial scheme 4x2 (four varieties x two products with four replicates. The presented results demonstrated the susceptibility of the fruits to the disease, mainly Maça variety with lesion of 17,99 mm. It was demosntrated the effectiveness of products at concentrations of 5ml. L-1 (Ecolife and 0.50g. L-1 (ASM on antracnosis control. The Figo variety presented the smallest injuries when treated with Ecolife (5.79 mm. Regarding ASM effects, Prata variety demonstrated the best performance, with 5.62 mm of injuries diameter

  3. Chapter 9. Benefits of International Collaboration | Science ...

    Science.gov (United States)

    In this chapter, we share what we have learned from working with our Brazilian colleagues on a multi university, multiyear, and multi basin ecological assessment and how those experiences were transmitted more broadly. These lessons (each of which is described in subsequent paragraphs) included 1) learning about markedly different ecosystems; 2) values to the U.S. Environmental Protection Agency (USEPA) of testing monitoring protocols in those ecosystems; 3) applying lessons from the CEMIG (Companhia Energética de Minas Gerais) project to research on other continents and elsewhere in Brazil; 4) advantages of academic team research; 5) benefits of corporate-sponsored research and federal student scholarships; 6) communicating with the general public; 7) the research web that has developed out of our work in Brazil; and 8) experiencing Brazilian culture. The USEPA’s NARS survey designs and field methods are being applied in large basin stream surveys in countries outside of the U.S. These applications not only provide valuable tests of the NARS approaches, but enhance International cooperation and generate new understandings of natural and anthropogenic controls on biota and physical habitat in streams. These understandings not only aid interpretation of the condition of streams in the regions surveyed, but also refine approaches for interpreting aquatic resource surveys elsewhere. In this book chapter, Robert Hughes and Philip Kaufmann describe th

  4. WIN Chapters: Milestones and Future Plans

    Energy Technology Data Exchange (ETDEWEB)

    Castro, P.; Pelegrí, M.

    2015-07-01

    In this paper the WIN Chapters: milestones and future plans are presented. WIN-IAEA has rewarded-in the three last years - to Australia-2014, South-Africa-2013 and Sweden-2012. WIN-Global -specially WiN IAEA- can collaborate a lot with the CTBTO presenting the content of the Treaty on the Non-Proliferation of Nuclear Weapons actually increasing the signatory members in 2015. Historical decisions on NTP are already affecting WiN IAEA. The research reactors or high flux reactors are important in the field of medical applications and other future applications. In Australia women-scientist of OPAL, can become WiN. Between the OPAL applications there is a production of silicon plates to be used in laptops/mobiles. WIN-Europe activities related with the climatic change and with the academic promotion. 2015 is also a very important year due the celebration of 20th Anniversary of WIN-Spain; plans of this Chapter and Conferences of WIN-Global are presented. In addition there are women working in ITER, in some activities in the EU, China, India, Japan, South Korea, USA and Russia both in the academic (R+D) field and into the Industry. (Author)

  5. Environment. Chapter 5; Medio ambiente. Capitulo 5

    Energy Technology Data Exchange (ETDEWEB)

    Martin del Castillo, Carlos [Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)

    2009-07-01

    In this chapter it is mentioned the concern for the care of the environment in Mexico by prominent foreign and Mexican scientists who impelled the creation of a Forest Law. The ecological policies for the conservation of natural resources that cause a sustainable development in Mexico are commented; it is described what the environmental infrastructure consists of; the case of trash handling is analyzed and the Chapter concludes with the relationship of the environment, the climatic change, the infrastructure and the planning. [Spanish] En este capitulo se menciona la preocupacion por el cuidado del medio ambiente en Mexico, por prominentes cientificos extranjeros y mexicanos que impulsaron la creacion de una Ley Forestal. Se comentan las politicas ecologicas para la conservacion de recursos naturales que propicien un desarrollo sustentable en Mexico; se describe en que consiste la infraestructura ambiental; se analiza el caso del manejo de la basura y; se concluye con la relacion del medio ambiente, el cambio climatico, la infraestructura y la planeacion.

  6. Map projections and the Internet: Chapter 4

    Science.gov (United States)

    Kessler, Fritz; Battersby, Sarah E.; Finn, Michael P.; Clarke, Keith

    2017-01-01

    The field of map projections can be described as mathematical, static, and challenging. However, this description is evolving in concert with the development of the Internet. The Internet has enabled new outlets for software applications, learning, and interaction with and about map projections . This chapter examines specific ways in which the Internet has moved map projections from a relatively obscure paper-based setting to a more engaging and accessible online environment. After a brief overview of map projections, this chapter discusses four perspectives on how map projections have been integrated into the Internet. First, map projections and their role in web maps and mapping services is examined. Second, an overview of online atlases and the map projections chosen for their maps is presented. Third, new programming languages and code libraries that enable map projections to be included in mapping applications are reviewed. Fourth, the Internet has facilitated map projection education and research especially with the map reader’s comprehension and understanding of complex topics like map projection distortion is discussed.

  7. Chapter 44: history of neurology in Italy.

    Science.gov (United States)

    Bentivoglio, Marina; Mazzarello, Paolo

    2010-01-01

    The chapter starts from the Renaissance (although the origins of Italian neurology can be traced back to the Middle Ages), when treatises of nervous system physiopathology still followed Hippocratic and Galenic "humoral" theories. In Italy, as elsewhere in Europe, the concepts of humoral pathology were abandoned in the 18th century, when neurology was influenced by novel trends. Neurology acquired the status of clinical discipline (as "clinic of mental diseases") after national reunification (declared in 1861 but completed much later). At the end of the 19th and first decades of the 20th century, eminent Italian "neuropsychiatrists" (including, among many others, Ugo Cerletti, who introduced electroconvulsive shock therapy in 1938) stimulated novel knowledge and approaches, "centers of excellence" flourished, and "Neurological Institutes" were founded. In the first half of the 20th century, the history of Italian neurology was dominated by World Wars I and II (which stimulated studies on the wounded) and the fascist regime in-between the Wars (when the flow of information was instead very limited). Italy became a republic in 1946, and modern neurology and its distinction from psychiatry were finally promoted. The chapter also provides detailed accounts of scientific societies and journals dedicated to the neurological sciences in Italy.

  8. An activated sludge modeling framework for xenobiotic trace chemicals (ASM-X): assessment of diclofenac and carbamazepine.

    Science.gov (United States)

    Plósz, Benedek Gy; Langford, Katherine H; Thomas, Kevin V

    2012-11-01

    Conventional models for predicting the fate of xenobiotic organic trace chemicals, identified, and calibrated using data obtained in batch experiments spiked with reference substances, can be limited in predicting xenobiotic removal in wastewater treatment plants (WWTPs). At stake is the level of model complexity required to adequately describe a general theory of xenobiotic removal in WWTPs. In this article, we assess the factors that influence the removal of diclofenac and carbamazepine in activated sludge, and evaluate the complexity required for the model to effectively predict their removal. The results are generalized to previously published cases. Batch experimental results, obtained under anoxic and aerobic conditions, were used to identify extensions to, and to estimate parameter values of the activated sludge modeling framework for Xenobiotic trace chemicals (ASM-X). Measurement and simulation results obtained in the batch experiments, spiked with the diclofenac and carbamazepine content of preclarified municipal wastewater shows comparably high biotransformation rates in the presence of growth substrates. Forward dynamic simulations were performed using full-scale data obtained from Bekkelaget WWTP (Oslo, Norway) to evaluate the model and to estimate the level of re-transformable xenobiotics present in the influent. The results obtained in this study demonstrate that xenobiotic loading conditions can significantly influence the removal capacity of WWTPs. We show that the trace chemical retransformation in upstream sewer pipes can introduce considerable error in assessing the removal efficiency of a WWTP, based only on parent compound concentration measurements. The combination of our data with those from the literature shows that solids retention time (SRT) can enhance the biotransformation of diclofenac, which was not the case for carbamazepine. Model approximation of the xenobiotic concentration, detected in the solid phase, suggest that between

  9. Rehabilitación integral y tolerancia al ejercicio físico en escolares asmáticos severos

    Directory of Open Access Journals (Sweden)

    . Héctor Alejandro Cruz Oliver

    1995-04-01

    Full Text Available Se realizó un estudio en 99 escolares asmáticos severos, incluidos en un programa de rehabilitación integral en el centro para niños asmáticos de la Ciudad de los Pioneros "José Martí" en Tarará, durante el curso escolar 1991-1992. A todos los escolares se les sometió antes de comenzar el programa, a una prueba de tolerancia al ejercicio físico mediante la carrera libre, y acorde con los resultados de ésta se clasificaron en 2 grupos; grupo I, con asma inducida por el ejercicio (AIE y grupo II, sin AIE. Al finalizar el programa de rehabilitación al grupo I se le sometió nuevamente a la prueba de tolerancia al ejercicio físico. Todos los escolares se evaluaron mediante la espirometría en condiciones basales antes del programa de rehabilitación y al finalizar éste. En 55 escolares (55,5 % se constató la presencia inicial de AIE. Al finalizar el programa de rehabilitación sólo en 23 de ellos se mantuvo este fenómeno. Con excepción de un escolar perteneciente al grupo I el resto de los niños toleraron sin dificultad las actividades físicas programadas. En relación con los parámetros de función respiratoria no se hallaron diferencias significativas en ninguno de ellos, cuando se compararon ambos grupos entre sí antes del programa de rehabilitación, y después de él. Comparando cada grupo consigo mismo sólo se observó un incremento significativo del flujo máximo medio (MMF en ambos grupos, lo que reflejó una disminución del componente obstructivo bronquial periférico.

  10. Investigation of the Stress Intensity Limits of ASME Section III Div.5 for Structure Design Criteria of SFR Fuel Assembly

    Energy Technology Data Exchange (ETDEWEB)

    Choo, Jin-Yup; Kim, Hyung-Kyu; Cheon, Jin-Sik [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2016-10-15

    These affect the mechanical design of the fuel assembly components. And thus, appropriate structural design criteria should also be chosen to incorporate the specific design conditions of the SFR fuel assemblies. Among them, the temperature is one of the most crucial conditions to be concerned because the sodium coolant temperature is normally more than 500ºC which is much higher than that of the LWR (< 350ºC). This implies that a thermal creep should be significantly considered in the SFR fuel assembly mechanical design. In addition to the high temperature condition, an irradiation swelling is also an important behavior that the SFR fuel assembly material should accommodate. To incorporate the temperature and irradiation impacts, the material of the fuel assembly components is presently determined to be made of HT-9, the ferriticmartensitic steel. In this paper, the ASME Sec. III Div. 5 (referred to as ‘Div. 5’ hereinafter), which was developed for a ‘high temperature reactor’, is considered as one of the structural design criteria for the mechanical design of SFR fuel assemblies. In this paper, the stress intensity limits, S{sub m} and S{sub t} of HT-9 were built for the structural criteria of an SFR fuel assembly. S{sub m} is obtained from the ultimate strength. As for S{sub t}, it is more complicated because of its dependency of time duration in addition to temperature. Following the definition of S{sub mt}, the method in the ASME Sec. III Div. 1, Subsec. NH was consulted. We found that the Sm is adopted as S{sub mt} under the temperature about 470ºC which is relatively low temperature range and over 470ºC with relatively short time duration as 1000 hours. And the S{sub t} is adopted as Smt at over 470ºC and long time duration over 34800 hours, and over 520ºC and 10{sup 4} hours too. And at over 570ºC and 1000 hours, and at over 630ºC and 100 hours, S{sub t} is also adopted for S{sub mt}.

  11. Materials for Liquid Propulsion Systems. Chapter 12

    Science.gov (United States)

    Halchak, John A.; Cannon, James L.; Brown, Corey

    2016-01-01

    Earth to orbit launch vehicles are propelled by rocket engines and motors, both liquid and solid. This chapter will discuss liquid engines. The heart of a launch vehicle is its engine. The remainder of the vehicle (with the notable exceptions of the payload and guidance system) is an aero structure to support the propellant tanks which provide the fuel and oxidizer to feed the engine or engines. The basic principle behind a rocket engine is straightforward. The engine is a means to convert potential thermochemical energy of one or more propellants into exhaust jet kinetic energy. Fuel and oxidizer are burned in a combustion chamber where they create hot gases under high pressure. These hot gases are allowed to expand through a nozzle. The molecules of hot gas are first constricted by the throat of the nozzle (de-Laval nozzle) which forces them to accelerate; then as the nozzle flares outwards, they expand and further accelerate. It is the mass of the combustion gases times their velocity, reacting against the walls of the combustion chamber and nozzle, which produce thrust according to Newton's third law: for every action there is an equal and opposite reaction. Solid rocket motors are cheaper to manufacture and offer good values for their cost. Liquid propellant engines offer higher performance, that is, they deliver greater thrust per unit weight of propellant burned. They also have a considerably higher thrust to weigh ratio. Since liquid rocket engines can be tested several times before flight, they have the capability to be more reliable, and their ability to shut down once started provides an extra margin of safety. Liquid propellant engines also can be designed with restart capability to provide orbital maneuvering capability. In some instances, liquid engines also can be designed to be reusable. On the solid side, hybrid solid motors also have been developed with the capability to stop and restart. Solid motors are covered in detail in chapter 11. Liquid

  12. Chapter 2: Stand-alone Applications - TOPCAT

    Science.gov (United States)

    Miller, C. J.

    Tool for OPerations on Catalogues And Tables or TOPCAT is a graphical viewer for table data. It offers a variety of ways to work with data tables, including a browser for the cell data, viewers for information about table and column metadata, dataset visualization, and even analysis. We discuss a small subset of TOPCAT's functionalities in this chapter. TOPCAT was originally developed as part of the Starlink program in the United Kingdom. It is now maintained by AstroGrid. The program is written in pure Java and available under the GNU General Public License. It is available for download and a version is included in the software distribution accompanying this book. TOPCAT is a GUI interface on top of the STIL library. A command line interface to this library, STILTS, described in Chapter 21 provides scriptable access to many of the capabilities described here. The purpose of this tutorial is to provide an overview of TOPCAT to the novice user. The best place to look for and learn about TOPCAT is the web page maintained by Mark B. Taylor. There, TOPCAT documentation is provided in HTML, PDF, via screen shots, etc. In this chapter we take the user through a few examples that give the general idea of how TOPCAT works. The majority of the functionality of TOPCAT is not included in this short tutorial. Our goal in this tutorial is to lead the reader through an exercise that would result in a publication quality figure (e.g. for a journal article). Specifically, we will use TOPCAT to show how the color-magnitude relation of a galaxy cluster compares to that of all galaxies in the Sloan Digital Sky Survey (York et al. 2000). This diagnostic is used not only in cluster finding, but its linear fit can provide insight into the age and/or metallicity of the oldest galaxies in galaxy clusters (which are some of the oldest galaxies in the Universe). The data we need for this exercise are: 1) the entire spectroscopic galaxy catalog from the SDSS, with galaxy positions, galaxy

  13. News from the Library: A new key reference work for the engineer: ASME's Boiler and Pressure Vessel Code at the CERN Library

    CERN Multimedia

    CERN Library

    2011-01-01

    The Library is aiming at offering a range of constantly updated reference books, to cover all areas of CERN activity. A recent addition to our collections strengthens our offer in the Engineering field.   The CERN Library now holds a copy of the complete ASME Boiler and Pressure Vessel Code, 2010 edition. This code establishes rules of safety governing the design, fabrication, and inspection of boilers and pressure vessels, and nuclear power plant components during construction. This document is considered worldwide as a reference for mechanical design and is therefore important for the CERN community. The Code published by ASME (American Society of Mechanical Engineers) is kept current by the Boiler and Pressure Committee, a volunteer group of more than 950 engineers worldwide. The Committee meets regularly to consider requests for interpretations, revision, and to develop new rules. The CERN Library receives updates and includes them in the volumes until the next edition, which is expected to ...

  14. instU_3d_asm_Cp: MERRA 3D IAU State, Meteorology Diurnal 1.25 x 1.25 degree V5.2.0 (MAIUCPASM) at GES DISC

    Data.gov (United States)

    National Aeronautics and Space Administration — The MAIUCPASM or instU_3d_asm_Cp data product is the MERRA Data Assimilation System 3-Dimensional assimilated state on pressure, at a reduced resolution. It is a...

  15. inst3_3d_asm_Cp: MERRA 3D IAU State, Meteorology Instantaneous 3-hourly 1.25 x 1.25 degree V5.2.0 (MAI3CPASM) at GES DISC

    Data.gov (United States)

    National Aeronautics and Space Administration — The MAI3CPASM or inst3_3d_asm_Cp data product is the MERRA Data Assimilation System 3-Dimensional assimilated state on pressure, at a reduced resolution. It is a...

  16. instM_3d_asm_Cp: MERRA 3D IAU State, Meteorology Monthly Mean 1.25 x 1.25 degree V5.2.0 (MAIMCPASM) at GES DISC

    Data.gov (United States)

    National Aeronautics and Space Administration — The MAIMCPASM or instM_3d_asm_Cp data product is the MERRA Data Assimilation System 3-Dimensional assimilated state on pressure, at a reduced resolution. It is a...

  17. 9 July 2012 - Academy of Sciences Malaysia (ASM), Chairman, Mathematical and Physical Sciences Discipline Group M. Yahaya FASc and his delegation visiting the LHC superconducting magnet test hall with Technology Department G. De Rijk.

    CERN Document Server

    Maximilien Brice

    2012-01-01

    9 July 2012 - Academy of Sciences Malaysia (ASM), Chairman, Mathematical and Physical Sciences Discipline Group M. Yahaya FASc and his delegation visiting the LHC superconducting magnet test hall with Technology Department G. De Rijk.

  18. const_2d_asm_Nx: MERRA DAS 2d constants 0.667 x 0.5 degree V5.2.0 (MAC0NXASM) at GES DISC

    Data.gov (United States)

    National Aeronautics and Space Administration — The MAC0NXASM or const_2d_asm_Nx data product is the MERRA Data Assimilation System 2-Dimensional Constants at native resolution. MERRA, or the Modern Era...

  19. Effect of beta2-adrenoceptor agonists and other cAMP-elevating agents on inflammatory gene expression in human ASM cells: a role for protein kinase A.

    Science.gov (United States)

    Kaur, Manminder; Holden, Neil S; Wilson, Sylvia M; Sukkar, Maria B; Chung, Kian Fan; Barnes, Peter J; Newton, Robert; Giembycz, Mark A

    2008-09-01

    In diseases such as asthma, airway smooth muscle (ASM) cells play a synthetic role by secreting inflammatory mediators such as granulocyte-macrophage colony-stimulating factor (GM-CSF), IL-6, or IL-8 and by expressing surface adhesion molecules, including ICAM-1. In the present study, PGE(2), forskolin, and short-acting (salbutamol) and long-acting (salmeterol and formoterol) beta(2)-adrenoceptor agonists reduced the expression of ICAM-1 and the release of GM-CSF evoked by IL-1beta in ASM cells. IL-1beta-induced IL-8 release was also repressed by PGE(2) and forskolin, whereas the beta(2)-adrenoceptor agonists were ineffective. In each case, repression of these inflammatory indexes was prevented by adenoviral overexpression of PKIalpha, a highly selective PKA inhibitor. These data indicate a PKA-dependent mechanism of repression and suggest that agents that elevate intracellular cAMP, and thereby activate PKA, may have a widespread anti-inflammatory effect in ASM cells. Since ICAM-1 and GM-CSF are highly NF-kappaB-dependent genes, we used an adenoviral-delivered NF-kappaB-dependent luciferase reporter to examine the effects of forskolin and the beta(2)-adrenoceptor agonists on NF-kappaB activation. There was no effect on luciferase activity measured in the presence of forskolin or beta(2)-adrenoceptor agonists. This finding is consistent with the observation that IL-1beta-induced expression of IL-6, a known NF-kappaB-dependent gene in ASM, was also unaffected by beta(2)-adrenoceptor agonists, forskolin, PGE(2), 8-bromo-cAMP, or rolipram. Collectively, these results indicate that repression of IL-1beta-induced ICAM-1 expression and GM-CSF release by cAMP-elevating agents, including beta(2)-adrenoceptor agonists, may not occur through a generic effect on NF-kappaB.

  20. Tamarix, hydrology and fluvial geomorphology: Chapter 7

    Science.gov (United States)

    Auerbach, Daniel A.; Merritt, David M.; Shafroth, Patrick B.; Sher, Anna A; Quigley, Martin F.

    2013-01-01

    This chapter explores the impact of hydrology and fluvial geomorphology on the distribution and abundance of Tamarix as well as the reciprocal effects of Tamarix on hydrologic and geomorphic conditions. It examines whether flow-regime alteration favors Tamarix establishment over native species, and how Tamarix stands modify processes involved in the narrowing of river channels and the formation of floodplains. It begins with an overview of the basic geomorphic and hydrologic character of rivers in the western United States before analyzing how this setting has contributed to the regional success of Tamarix. It then considers the influence of Tamarix on the hydrogeomorphic form and function of rivers and concludes by discussing how a changing climate, vegetation management, and continued water-resource development affect the future role of Tamarix in these ecosystems.

  1. Environment-effect reporting. Chapter 6

    International Nuclear Information System (INIS)

    Hermens, P.A.H.

    1989-01-01

    Environment-effect reporting is a tool in the resolution of one or more government bodies about activities which may have important disadvantageous impacts upon the environment. This chapter gives a treatment of environment-effect reporting as a process consisting of the preparation, draw-up, judgement and use of an environment-effect report (MER), followed by an evaluation. The contentsof an environment-effect report are indicated. The role of environment-effect reporting in relation with other procedures is discussed. Some experience with the application of environment-effect reporting is presented and a number of experiences in the application are discussed. (H.W.). 5 refs.; 3 figs.; 3 tabs

  2. History of Artificial Gravity. Chapter 3

    Science.gov (United States)

    Clement, Gilles; Bukley, Angie; Paloski, William

    2006-01-01

    This chapter reviews the past and current projects on artificial gravity during space missions. The idea of a rotating wheel-like space station providing artificial gravity goes back in the writings of Tsiolkovsky, Noordung, and Wernher von Braun. Its most famous fictional representation is in the film 2001: A Space Odyssey, which also depicts spin-generated artificial gravity aboard a space station and a spaceship bound for Jupiter. The O Neill-type space colony provides another classic illustration of this technique. A more realistic approach to rotating the space station is to provide astronauts with a smaller centrifuge contained within a spacecraft. The astronauts would go into it for a workout, and get their gravity therapeutic dose for a certain period of time, daily or a few times a week. This simpler concept is current being tested during ground-based studies in several laboratories around the world.

  3. Granulomatose broncocêntrica idiopática em jovem não asmática

    Directory of Open Access Journals (Sweden)

    Santos José Wellington Alves dos

    2003-01-01

    Full Text Available Granulomatose broncocêntrica é um achado histopatológico descritivo, caracterizado pela inflamação granulomatosa necrosante, centrada em brônquios e bronquíolos, e que ocorre associada a doenças infecciosas, imunológicas e neoplásicas, ou de forma idiopática. Este trabalho relata o caso de uma jovem não asmática de 26 anos com dor torácica, febre e tosse produtiva havia um mês, que apresentou consolidação e cavitação em segmento lingular, observadas na radiografia e na tomografia computadorizada de tórax. Punção aspirativa transbrônquica evidenciou lesão inflamatória inespecífica, sem etiologia identificada. O exame histológico de material obtido por biópsia pulmonar a céu aberto foi compatível com granulomatose broncocêntrica idiopática. Após tratamento com prednisona, houve melhora clínica, sem recidivas.

  4. CEASEMT system: the TEDEL code. Pipings - Plasticity - Dynamics - Statics - Buckling - Thermoplasticity - Creep - Large displacements - FLUIDS - SEISMS - ASME

    International Nuclear Information System (INIS)

    Hoffmann, Alain; Jeanpierre, Francoise; Axisa, Francois; Chevalier, Gerard; Lepareux, Michel.

    1977-01-01

    The TEDEL code is intended for elastic and plastic computation of three-dimensional pipes and frames with possible junction to shells. The structures are described with using assemblies of beam elements, or piping elements such as, curved pipes, 90 0 elbows, tees, any elements, the stiffness properties of which are given to TEDEL. TEDEL allows the dynamic computation of the structures: search of eigenfrequencies and eigenmodes of vibration, time response to any time-dependent canvassing. This response can be obtained either from recombining a number of eigenmodes, or from a direct numerical integration of the dynamics equation. In these last two cases TEDEL accounts for some possible damping. A TEDEL option allows critical buckling loads to be computed (Euler). The structures can offer any shapes comprising any number of materials. The data are readout without any format, and distributed in optional commands with a precise physical meaning: GEOMETRY, MATERIALS, LOAD, COMPUTATION, END. A dynamical memory control allows the size of the routine to be adapted to the problem to be treated. For pipings, an option is intended for an automatic checking of the stress level with regard to the limiting values of the ASME. Geometrical data, node positions, element numbering are given by COCO which also delivers perspective drawings for the structure to be studied. The results on magnetic tapes can be treated by the subroutines ESPACE-VISU-TEMPS [fr

  5. More on fatigue verification of Class 1 nuclear power piping according to ASME BPV III NB-3600

    International Nuclear Information System (INIS)

    Zeng, Lingfu; Dahlström, Lars; Jansson, Lennart G.

    2011-01-01

    In this paper, fatigue verification of Class 1 nuclear power piping according to ASME Boiler and Pressure Vessel Code, Section III, NB-3600, and relevant issues that are often discussed in connection to the power uprate of several Swedish BWR reactors in recent years, are dealt with. Key parameters involved in the fatigue verification, i.e. the alternating stress intensity S alt , the penalty factor K e and the cumulative damage factor U, and relevant computational procedures applicable for the assessment of low-cycle fatigue failure using strain-controlled data, are particularly addressed. A so-called simplified elastic-plastic discontinuity analysis for alternative verification when basic fatigue requirements found unsatisfactory, and the procedures provided in NB-3600 for evaluating the alternating stress intensity S alt , are reviewed in detail. Our emphasis is placed on other procedures alternative to the simplified elastic-plastic discontinuity analysis. A more in-depth discussion is given to an alternative suggested earlier by the authors using nonlinear finite element analyses. This paper is a continuation of our work presented in ICONE16/17/18, which attempted to categorize design rules in the code into linear design rules and non-linear design rules and to clarify corresponding design requirements and finite element analyses, in particular, those non-linear ones. (author)

  6. Report on the FY17 Development of Computer Program for ASME Section III, Division 5, Subsection HB, Subpart B Rules

    Energy Technology Data Exchange (ETDEWEB)

    Swindeman, M. J. [Argonne National Lab. (ANL), Argonne, IL (United States); Jetter, R. I. [Argonne National Lab. (ANL), Argonne, IL (United States); Sham, T. -L. [Argonne National Lab. (ANL), Argonne, IL (United States)

    2017-01-01

    One of the objectives of the high temperature design methodology activities is to develop and validate both improvements and the basic features of ASME Boiler and Pressure Vessel Code, Section III, Rules for Construction of Nuclear Facility Components, Division 5, High Temperature Reactors, Subsection HB, Subpart B (HBB). The overall scope of this task is to develop a computer program to aid assessment procedures of components under specified loading conditions in accordance with the elevated temperature design requirements for Division 5 Class A components. There are many features and alternative paths of varying complexity in HBB. The initial focus of this computer program is a basic path through the various options for a single reference material, 316H stainless steel. However, the computer program is being structured for eventual incorporation all of the features and permitted materials of HBB. This report will first provide a description of the overall computer program, particular challenges in developing numerical procedures for the assessment, and an overall approach to computer program development. This is followed by a more comprehensive appendix, which is the draft computer program manual for the program development. The strain limits rules have been implemented in the computer program. The evaluation of creep-fatigue damage will be implemented in future work scope.

  7. Optimization of A(2)O BNR processes using ASM and EAWAG Bio-P models: model performance.

    Science.gov (United States)

    El Shorbagy, Walid E; Radif, Nawras N; Droste, Ronald L

    2013-12-01

    This paper presents the performance of an optimization model for a biological nutrient removal (BNR) system using the anaerobic-anoxic-oxic (A(2)O) process. The formulated model simulates removal of organics, nitrogen, and phosphorus using a reduced International Water Association (IWA) Activated Sludge Model #3 (ASM3) model and a Swiss Federal Institute for Environmental Science and Technology (EAWAG) Bio-P module. Optimal sizing is attained considering capital and operational costs. Process performance is evaluated against the effect of influent conditions, effluent limits, and selected parameters of various optimal solutions with the following results: an increase of influent temperature from 10 degrees C to 25 degrees C decreases the annual cost by about 8.5%, an increase of influent flow from 500 to 2500 m(3)/h triples the annual cost, the A(2)O BNR system is more sensitive to variations in influent ammonia than phosphorus concentration and the maximum growth rate of autotrophic biomass was the most sensitive kinetic parameter in the optimization model.

  8. Modeling nitrous oxide production during biological nitrogen removal via nitrification and denitrification: extensions to the general ASM models.

    Science.gov (United States)

    Ni, Bing-Jie; Ruscalleda, Maël; Pellicer-Nàcher, Carles; Smets, Barth F

    2011-09-15

    Nitrous oxide (N(2)O) can be formed during biological nitrogen (N) removal processes. In this work, a mathematical model is developed that describes N(2)O production and consumption during activated sludge nitrification and denitrification. The well-known ASM process models are extended to capture N(2)O dynamics during both nitrification and denitrification in biological N removal. Six additional processes and three additional reactants, all involved in known biochemical reactions, have been added. The validity and applicability of the model is demonstrated by comparing simulations with experimental data on N(2)O production from four different mixed culture nitrification and denitrification reactor study reports. Modeling results confirm that hydroxylamine oxidation by ammonium oxidizers (AOB) occurs 10 times slower when NO(2)(-) participates as final electron acceptor compared to the oxic pathway. Among the four denitrification steps, the last one (N(2)O reduction to N(2)) seems to be inhibited first when O(2) is present. Overall, N(2)O production can account for 0.1-25% of the consumed N in different nitrification and denitrification systems, which can be well simulated by the proposed model. In conclusion, we provide a modeling structure, which adequately captures N(2)O dynamics in autotrophic nitrification and heterotrophic denitrification driven biological N removal processes and which can form the basis for ongoing refinements.

  9. A Retrospective Look at 20 Years of ASM Education Programs (1990-2010) and a Prospective Look at the Next 20 Years (2011-2030).

    Science.gov (United States)

    Chang, Amy

    2011-01-01

    Professional societies provide visibility and legitimacy to the work of their post secondary educator members, advocate best practices in courses and sponsored student research, and establish deep networks and communities that catalyze members to collectively engage in undergraduate teaching and learning scholarship. Within the American Society for Microbiology (ASM), the Education Board, established in the mid-1970s, assumes this role. I have been fortunate enough to watch several pivotal programs support our growth and change the status quo by providing opportunities for biology educators to flourish. In this retrospective review, the background and details I offer about each initiative help explain ASM Education offerings, how our growth has been supported and how the status quo has changed. In this prospective look, I offer my vision of the future in post secondary education where classroom learning is student-centered and focused on global problems affecting our health and environment. For the profession to proliferate, the ASM must provide members as many opportunities in learning biology as they do with advancing biology to new frontiers.

  10. DFT study of isomers of the ruthenium dihydride complex RuH2(CO)2(AsMe2Ph)2.

    Science.gov (United States)

    Said, R Ben; Essalah, K; Sanhoury, M A K; Hussein, K; Boughdiri, S; Chermette, H

    2017-04-01

    A density functional theory (DFT) study of cct-As, ccc, and cct-CO isomers of the ruthenium dihydride complex RuH 2 (CO) 2 (AsMe 2 Ph) 2 is reported (see Scheme for the labeling isomer 34 structures of RuH 2 (CO) 2 (AsMe 2 Ph) 2 ). Complex geometries and relative energies of different isomers have been calculated with both B3LYP and M06-2X functionals. The results show that the B3LYP calculated Boltzmann populations of cct-As, ccc, and cct-CO isomers are 65.5, 34.2, and 0.3%, respectively. These are in better agreement with the experimental data than those calculated at the M06-2X level. However, the calculations of 1 H NMR chemical shifts were found to be better described with M06-2X than with B3LYP or with HF level of theories. In addition, a transition state between the two most stable isomers was determined through DFT/(B3LYP or M06-2X) calculations. Graphical Abstract Scheme: Labeling structure of RuH 2 (CO) 2 (AsMe 2 Ph) 2 .

  11. Health and mental health care utilization by clients of resources for homeless persons in quebec city and montreal, Canada: a 5-year follow-up study.

    Science.gov (United States)

    Bonin, Jean-Pierre; Fournier, Louise; Blais, Régis; Perreault, Michel; White, Noé Djawn

    2010-01-01

    The objective of this cohort study is to describe the service utilization by clients of homeless resources in Quebec and Montreal (Canada) over a 5-year period. Participants (N = 426) were recruited from a survey conducted in 1999 about clients' utilization of resources intended for homeless people in Montreal and Quebec. Data analyzed in this study were also drawn from three administrative databanks managed by the Quebec health care system. Results revealed that: (1) in general, mental health services are less used than physical health services; (2) generally, women, older persons, nonhomeless persons, and persons with mental health problems utilized proportionately more health services; and (3) participants involved in this study tend to continue using services over years in a system where health services are free. These findings are discussed in terms of long-term service utilization by clients of homeless resources.

  12. Individual- and area-level disparities in access to the road network, subway system and a public bicycle share program on the Island of Montreal, Canada.

    Science.gov (United States)

    Fuller, Daniel; Gauvin, Lise; Kestens, Yan

    2013-02-01

    Few studies have examined potential disparities in access to transportation infrastructures, an important determinant of population health. To examine individual- and area-level disparities in access to the road network, public transportation system, and a public bicycle share program in Montreal, Canada. Examining associations between sociodemographic variables and access to the road network, public transportation system, and a public bicycle share program, 6,495 adult respondents (mean age, 48.7 years; 59.0 % female) nested in 33 areas were included in a multilevel analysis. Individuals with lower incomes lived significantly closer to public transportation and the bicycle share program. At the area level, the interaction between low-education and low-income neighborhoods showed that these areas were significantly closer to public transportation and the bicycle share program controlling for individual and urbanicity variables. More deprived areas of the Island of Montreal have better access to transportation infrastructure than less-deprived areas.

  13. Chapter 2 : X and gamma ray secondary standard metrology

    Energy Technology Data Exchange (ETDEWEB)

    Peixoto, JoseGuilherme Pereira; Potiens, Maria da Penha

    2014-07-01

    Chapter 2 presents: an introduction; SSDL responsibilities; Determination of a calibration coefficient: The model equation; Dosimetry Protocols: codes of practice in radiotherapy, diagnostic radiology and radiation protection)

  14. Impacts on integrated spatial and infrastructure planning (Chapter18)

    CSIR Research Space (South Africa)

    Van Huyssteen, Elsona

    2016-01-01

    Full Text Available stream_source_info Van Huyssteen_2016.pdf.txt stream_content_type text/plain stream_size 193754 Content-Encoding UTF-8 stream_name Van Huyssteen_2016.pdf.txt Content-Type text/plain; charset=UTF-8 CHAPTER 18: IMPACTS... ON INTEGRATED SPATIAL AND INFRASTRUCTURE PLANNING CHAPTER 18 Impacts on Integrated Spatial and Infrastructure Planning CHAPTER 18: IMPACTS ON INTEGRATED SPATIAL AND INFRASTRUCTURE PLANNING Page 18-1 CHAPTER 18: IMPACTS ON INTEGRATED SPATIAL...

  15. Case study of the propagation of a small flaw under PWR loading conditions and comparison with the ASME code design life. Comparison of ASME Code Sections III and XI

    International Nuclear Information System (INIS)

    Yahr, G.T.; Gwaltney, R.C.; Richardson, A.K.; Server, W.L.

    1986-01-01

    A cooperative study was performed by EG and G Idaho, Inc., and Oak Ridge National Laboratory to investigate the degree of conservatism and consistency in the ASME Boiler and Pressure Vessel Code Section III fatigue evaluation procedure and Section XI flaw acceptance standards. A single, realistic, sample problem was analyzed to determine the significance of certain points of criticism made of an earlier parametric study by staff members of the Division of Engineering Standards of the Nuclear Regulatory Commission. The problem was based on a semielliptical flaw located on the inside surface of the hot-leg piping at the reactor vessel safe-end weld for the Zion 1 pressurized-water reactor (PWR). Two main criteria were used in selecting the problem; first, it should be a straight pipe to minimize the computational expense; second, it should exhibit as high a cumulative usage factor as possible. Although the problem selected has one of the highest cumulative usage factors of any straight pipe in the primary system of PWRs, it is still very low. The Code Section III fatigue usage factor was only 0.00046, assuming it was in the as-welded condition, and fatigue crack-growth analyses predicted negligible crack growth during the 40-year design life. When the analyses were extended past the design life, the usage factor was less than 1.0 when the flaw had propagated to failure. The current study shows that the criticism of the earlier report should not detract from the conclusion that if a component experiences a high level of cyclic stress corresponding to a fatigue usage factor near 1.0, very small cracks can propagate to unacceptable sizes

  16. The Challenges of the Local Management of Ethnic-Religious Diversity in Montreal: The Case of the Fitting Out of Places of Worship

    Directory of Open Access Journals (Sweden)

    Annick Germain

    2007-06-01

    Full Text Available Based on the case of Montreal, the author reviews the set of experiences of public intervention in the area of management of ethnic-religious diversity, which has led to the formulation of new debates with regard to the fit of this plurality in the urban space. The challenges posed by the incorporation of these new religious references in the configuring of the urban fabric also opens up questions on the meaning of cohabitation in increasingly plural neighbourhoods.

  17. Numerical Prediction of Dust. Chapter 10

    Science.gov (United States)

    Benedetti, Angela; Baldasano, J. M.; Basart, S.; Benincasa, F.; Boucher, O.; Brooks, M.; Chen, J. P.; Colarco, P. R.; Gong, S.; Huneeus, N.; hide

    2013-01-01

    Covers the whole breadth of mineral dust research, from a scientific perspective Presents interdisciplinary work including results from field campaigns, satellite observations, laboratory studies, computer modelling and theoretical studies Explores the role of dust as a player and recorder of environmental change This volume presents state-of-the-art research about mineral dust, including results from field campaigns, satellite observations, laboratory studies, computer modelling and theoretical studies. Dust research is a new, dynamic and fast-growing area of science and due to its multiple roles in the Earth system, dust has become a fascinating topic for many scientific disciplines. Aspects of dust research covered in this book reach from timescales of minutes (as with dust devils, cloud processes, and radiation) to millennia (as with loess formation and oceanic sediments), making dust both a player and recorder of environmental change. The book is structured in four main parts that explore characteristics of dust, the global dust cycle, impacts of dust on the Earth system, and dust as a climate indicator. The chapters in these parts provide a comprehensive, detailed overview of this highly interdisciplinary subject. The contributions presented here cover dust from source to sink and describe all the processes dust particles undergo while travelling through the atmosphere. Chapters explore how dust is lifted and transported, how it affects radiation, clouds, regional circulations, precipitation and chemical processes in the atmosphere, and how it deteriorates air quality. The book explores how dust is removed from the atmosphere by gravitational settling, turbulence or precipitation, how iron contained in dust fertilizes terrestrial and marine ecosystems, and about the role that dust plays in human health. We learn how dust is observed, simulated using computer models and forecast. The book also details the role of dust deposits for climate reconstructions

  18. Petro-Canada's project to add petroleum product storage tanks to the Municipality of Montreal-East

    International Nuclear Information System (INIS)

    Lefebvre, G.; Joly, R.; Guay, T.

    2006-01-01

    This paper explored the environmental impacts associated with Petro-Canada's project to add petroleum product storage tanks to its refinery in the east-end of Montreal. The project plan is based on a 6 year horizon from 2006-2012. The additional reservoirs would store new products destined for the petrochemical industry and for consumers, thus improving the flexibility and reliability of the refinery. The products would include low sulfur diesel and ethanol gasoline. The project does not involve any increase in refining capacity, and is estimated to cost $15 million. The main issues associated with this project are ambient air quality, the protection of groundwater and soil, as well as the security of areas inhabited by neighbouring areas in risk of a major accident. Emissions of organic compounds, including benzene, are considered minimal considering the use of sealed floating roofs. Geomembranes will be installed under the storage tanks to ensure the protection of groundwater and soil. Any consequences to the population of neighbouring areas resulting from accidents inside the industrial park will be limited since the reservoirs will be located more than 1 km away from a populated area. Quebec's Ministry of Sustainable Development, Environment and Parks recommended that this project be approved as long as the terms and measures of environmental regulations are respected, and that an emergency plan is submitted before the operation of the first reservoir. 1 tab

  19. Oscillating in and out of place: Experiences of older adults residing in homeless shelters in Montreal, Quebec.

    Science.gov (United States)

    Burns, Victoria F

    2016-12-01

    Aging in place is desirable from the perspective of older adults and policy makers alike. However, the meaning of 'place' for adults experiencing homelessness has been largely overlooked. Addressing this gap, this constructivist grounded theory study discusses the meaning of place for 15 older adults residing in emergency homeless shelters in Montreal, Quebec. Findings revealed that four interrelated dimensions of place-that is, control, comfort, privacy, and security were instrumental in supporting participants' ability to feel in place across housed-homeless trajectories. Many felt out of place well before they lost their housing and some felt more in place during homelessness when shelter conditions and interpersonal relations supported these four dimensions. The empirically-driven model oscillating in and out of place extends and nuances existing understandings of aging in place and provides insights into policy and practice solutions for older adults who may not have a stable place to call home. Copyright © 2016 Elsevier Inc. All rights reserved.

  20. Is gentrification all bad? Positive association between gentrification and individual's perceived neighborhood collective efficacy in Montreal, Canada.

    Science.gov (United States)

    Steinmetz-Wood, Madeleine; Wasfi, Rania; Parker, George; Bornstein, Lisa; Caron, Jean; Kestens, Yan

    2017-07-14

    Collective efficacy has been associated with many health benefits at the neighborhood level. Therefore, understanding why some communities have greater collective efficacy than others is important from a public health perspective. This study examined the relationship between gentrification and collective efficacy, in Montreal Canada. A gentrification index was created using tract level median household income, proportion of the population with a bachelor's degree, average rent, proportion of the population with low income, and proportion of the population aged 30-44. Multilevel linear regression analyses were conducted to measure the association between gentrification and individual level collective efficacy. Gentrification was positively associated with collective efficacy. Gentrifiers (individuals moving into gentrifying neighborhoods) had higher collective efficacy than individuals that lived in a neighborhood that did not gentrify. Perceptions of collective efficacy of the original residents of gentrifying neighborhoods were not significantly different from the perceptions of neighborhood collective efficacy of gentrifiers. Our results indicate that gentrification was positively associated with perceived collective efficacy. This implies that gentrification could have beneficial health effects for individuals living in gentrifying neighborhoods.

  1. Academic performance and educational pathways of young allophones: A comparative multivariate analysis of Montreal, Toronto, and Vancouver

    Directory of Open Access Journals (Sweden)

    Jacques Ledent

    2013-01-01

    Full Text Available Using several local and provincial data banks enabling one to follow the school progression of the cohort of students who, in Canada’s three main immigration-destination cities, were expected to graduate secondary school in 2004, this article examines the academic performance and educational pathways of those students who at home use a language other the main language of schooling: non-French speakers in Montreal and non-English speakers in Toronto and Vancouver. First, after accounting for differences in characteristics, those students (target group are shown to succeed better than the remaining students (comparison group, especially in Vancouver. However, within the target group, there appear to be substantial differences in performance between linguistic subgroups, which are far from being similar in all three cities. Second, the individual and contextual factors that influence the academic performance of the students in the target group appear to be similar for some and different for others in the three cities, while presenting some more-or-less large discrepancies with the corresponding factors pertaining to the comparison group. The article concludes with a few policy implications.

  2. The NAA method at Polytechnique Montreal. An efficient alternative way to use the k0 NAA models

    International Nuclear Information System (INIS)

    Chilian, C.; Kennedy, G.

    2014-01-01

    At Ecole Polytechnique Montreal, the philosophy in performing neutron activation analysis (NAA) is long-term and application oriented. Thinking long-term implies a good understanding of the fundamentals of the method, of the samples, of the tools, reactor and detectors, and there must be constant innovation that is experimentally validated with extensive measurements. Application oriented means a NAA method developed to provide users with fast, sensitive, accurate and reliable analyses for various types of materials. This philosophy dictates the manner in which the developments in the areas of NAA software, peak-area calculation, dead-time correction, detection efficiency model, k 0 and Q 0 values, neutron moderation and neutron self-shielding are carried out. This paper presents a survey of the Laboratory’s methodology, reviewing a few of its unique features such as detector efficiency calibration and sample related perturbations of the neutron activation. These features are used as examples to provide the reader with an understanding of the philosophy and the evolution of the NAA method at Ecole Polytechnique. (author)

  3. Comparison of Montreal Cognitive Assessment and Mini-Mental State Examination in Evaluating Cognitive Domain Deficit Following Aneurysmal Subarachnoid Haemorrhage

    Science.gov (United States)

    Wong, George Kwok Chu; Lam, Sandy Wai; Wong, Adrian; Ngai, Karine; Poon, Wai Sang; Mok, Vincent

    2013-01-01

    Objective Cognitive deficits are common after aneurysmal subarachnoid haemorrhage (aSAH), and clinical evaluation is important for their management. Our hypothesis was that the Montreal Cognitive Assessment (MoCa) is superior to the Mini-Mental State Examination (MMSE) in screening for cognitive domain deficit in aSAH patients. Methods We carried out a prospective observational and diagnostic accuracy study on Hong Kong aSAH patients aged 21 to 75 years who had been admitted within 96 hours of ictus. The domain-specific neuropsychological assessment battery, the MoCA and MMSE were administered 2–4 weeks and 1 year after ictus. A cognitive domain deficit was defined as a cognitive domain z score ictus, the MoCA produced higher area under the curve scores for cognitive impairment than the MMSE (MoCA, 0.92; 95% CI, 0.83 to 0.97 versus MMSE, 0.77; 95% CI, 0.66 to 0.83, p = 0.009). Interpretation Cognitive domain deficits and cognitive impairment in patients with aSAH can be screened with the MoCA in both the subacute and chronic phases. PMID:23573223

  4. Academic performance and educational pathways of young allophones: A comparative multivariate analysis of Montreal, Toronto, and Vancouver

    Directory of Open Access Journals (Sweden)

    Jacques Ledent

    2013-05-01

    Full Text Available Using several local and provincial data banks enabling one to follow the school progression of the cohort of students who, in Canada’s three main immigration-destination cities, were expected to graduate secondary school in 2004, this article examines the academic performance and educational pathways of those students who at home use a language other the main language of schooling: non-French speakers in Montreal and non-English speakers in Toronto and Vancouver. First, after accounting for differences in characteristics, those students (target group are shown to succeed better than the remaining students (comparison group, especially in Vancouver. However, within the target group, there appear to be substantial differences in performance between linguistic subgroups, which are far from being similar in all three cities. Second, the individual and contextual factors that influence the academic performance of the students in the target group appear to be similar for some and different for others in the three cities, while presenting some more-or-less large discrepancies with the corresponding factors pertaining to the comparison group. The article concludes with a few policy implications.

  5. Validation studies of the Portuguese experimental version of the Montreal Cognitive Assessment (MoCA): confirmatory factor analysis.

    Science.gov (United States)

    Duro, Diana; Simões, Mário R; Ponciano, Emanuel; Santana, Isabel

    2010-05-01

    The Montreal Cognitive Assessment (MoCA) is a cognitive screening instrument created with the purpose of overcoming some of the insufficiencies of the Mini-Mental State Examination (MMSE). The MoCA evaluates more cognitive areas and is comprised of more complex tasks as compared with the MMSE, which makes it a more sensitive instrument in the detection of Mild Cognitive Impairment (MCI), a state that often progresses to dementia. In this study we performed an analysis of the psychometric and diagnostic properties of the Portuguese experimental version of the MoCA in a clinical sample of 212 subjects with MCI and several dementia subtypes in a memory clinic setting. Additionally, we performed a Confirmatory Factor Analysis (CFA) to assess the MoCA's latent factorial structure. In a clinical population, the MoCA is a valid and reliable instrument with good psychometric properties, revealing high sensitivity in identifying MCI and dementia patients who generally score within the normal range on the MMSE. By using the parcels method, CFA results showed very good/excellent adjustment indexes. The practical implications of this CFA study allow us to propose a two factor model factorial structure for the MoCA: a first factor designated Memory, which includes memory, language and orientation subtests (the latter being closely correlated with the former), and a second factor designated Attention/Executive Functions, comprised of attention, executive functions and visuospacial abilities tasks.

  6. Recent actions taken on methyl bromide under the Montreal Protocol: Their potential economic implications on international trade

    International Nuclear Information System (INIS)

    Ross, R.T.; Vail, P.V.

    1993-01-01

    Methyl bromide (MB) produced and used by man is a versatile, highly effective, fastacting fumigant employed in a number of important ways to kill organisms destructive to plants. A wide spectrum of commodities is treated with MB. The compound is unique in that it provides a wide range of pest control, may be applied to a broad spectrum of both food and non-food commodities, can be used for fumigation of large and small quantities of materials, and, when applied properly, leaves no residues of toxicological significance. Recently, this compound has come under scientific scrutiny and has been identified as a potentially potent ozone depleting chemical. As a result, countries operating under the Montreal Protocol will be restricting its use, and, in some cases, eliminating its use altogether. To date there are no alternative chemical fumigants to replace methyl bromide. Non-chemical treatments such as irradiation, hot and cold treatments, modified atmosphere, etc., are the most promising. The paper focuses on the magnitude of the economic consequences on international trade and the necessity to have available alternative treatments that are highly effective, fast-acting, and practical. 8 refs, 12 tabs

  7. Montreal Battery of Evaluation of Amusia: Validity evidence and norms for adolescents in Belo Horizonte, Minas Gerais, Brazil

    Directory of Open Access Journals (Sweden)

    Marília Nunes-Silva

    Full Text Available ABSTRACT The Montreal Battery of Evaluation of Amusia (MBEA is a battery of tests that assesses six music processing components: scale, contour, interval, rhythm, metric, and music memory. The present study sought to verify the psychometric characteristics of the MBEA in a sample of 150 adolescents aged 14-18 years in the city of Belo Horizonte, Minas Gerais, Brazil, and to develop specific norms for this population. We used statistical procedures that explored the dimensional structure of the MBEA and its items, evaluating their adequacy from empirical data, verifying their reliability, and providing evidence of validity. The results for the difficult levels for each test indicated a trend toward higher scores, corroborating previous studies. From the analysis of the criterion groups, almost all of the items were considered discriminatory. The global score of the MBEA was shown to be valid and reliable (r K-R20=0.896 for assessing the musical ability of normal teenagers. Based on the analysis of the items, we proposed a short version of the MBEA. Further studies with larger samples and amusic individuals are necessary to provide evidence of the validity of the MBEA in the Brazilian milieu. The present study brings to the Brazilian context a tool for diagnosing deficits in musical skills and will serve as a basis for comparisons with single case studies and studies of populations with specific neuropsychological syndromes.

  8. How do dentists perceive poverty and people on social assistance? A qualitative study conducted in Montreal, Canada.

    Science.gov (United States)

    Loignon, Christine; Landry, Anne; Allison, Paul; Richard, Lucie; Bedos, Christophe

    2012-05-01

    Despite significant needs, people on social assistance are sometimes reluctant to consult dentists because of previous negative experience and communication barriers. They feel poorly understood by oral health professionals and sometimes complain of being stigmatized. It is thus important to know how dentists perceive poverty and this group of patients. The aim of this study was to understand how dentists perceive poverty and people on social assistance. To investigate this largely unexplored question, a qualitative study was conducted based on in-depth interviews with thirty-three dentists practicing in Montreal, Canada. Interviews were audiotaped and transcribed for qualitative analysis. The study revealed two perspectives on poverty: 1) the individualistic-deficit perspective and 2) the socio-lifecourse perspective. In the individualistic-deficit perspective, which predominated among these participants, dentists explained poverty by individual factors and emphasized individuals' negative attitudes toward work and lack of capabilities. Conversely, dentists with a socio-lifecourse perspective described poverty as a structural rather than an individual process. Acknowledging individuals' distress and powerlessness, these dentists expressed more empathy toward people on social assistance. The results suggest the individualistic-deficit perspective impedes the care relationship between dentists and poor patients as well as highlighting the need to better prepare dentists for addressing issues of poverty and social inequities in clinical practice.

  9. Calidad de vida en el adolescente asmático Quality of life in the asthmatic adolescent

    Directory of Open Access Journals (Sweden)

    Orquídea Aguirre Pérez

    2010-12-01

    Full Text Available INTRODUCCIÓN: la mejoría de la calidad de vida es clave en el tratamiento del niño-adolescente con asma. OBJETIVO: identificar la afectación que provoca el asma bronquial en la calidad de vida del adolescente asmático. MÉTODOS: se realizó un estudio descriptivo, longitudinal y prospectivo de 103 adolescentes asmáticos con diagnóstico de asma leve intermitente, asma leve persistente y asma moderada persistente en la Escuela Secundaria Básica "Antonio José de Sucre", en la localidad de Cojímar, en el período entre el 1ro. de enero de 2006 y el 31 de diciembre del propio año. RESULTADOS: los síntomas principales fueron la tos, la disnea y la sibilancia, y las molestias más frecuentes, el cansancio, la dificultad para respirar hondo y la sensación de quedar sin aire. Predominó el sexo masculino y las edades de 12 y 13 años. El mayor número de respuestas de las alteraciones de la función emocional se concentraba en las categorías más bajas del nivel de afectación, y las respuestas sobre la limitación de la actividad motora se inclinaron hacia las categorías de muchísimo, mucho, bastante y regular. Predominó la afectación moderada de la calidad de vida. El asma persistente moderada fue la mayormente referida en la afectación de calidad de vida severa.INTRODUCTION: the improvement in quality of life is a key element in treatment of asthmatic child-adolescent. OBJECTIVE: to identify the affection provoking the bronchial asthma in the quality of life of the asthmatic adolescent. METHODS: a prospective longitudinal and descriptive study was conducted in 103 asthmatic adolescents diagnosed with intermittent slight asthma from the "Antonio José de Sucre" Secondary Basic School in the Cojimar place, from January 1, to December 31, 2006. RESULTS: the major symptoms included cough, dyspnea and sibilation and the more frequent nuisances were the tiredness, profound breathlessness and the feeling of lack of air. There was

  10. Moving forward with imperfect information: chapter 19

    Science.gov (United States)

    Averyt, Kristen; Brekke, Levi D.; Kaatz, Laurna; Welling, Leigh; Hartge, Eric H.; Iseman, Tom

    2013-01-01

    This chapter summarized the scope of what is known and not known about climate in the Southwestern United States. There is now more evidence and more agreement among climate scientists about the physical climate and related impacts in the Southwest compared with that represented in the 2009 National Climate Assessment (Karl, Melillo, and Peterson 2009). However, there remain uncertainties about the climate system, the complexities within climate models, the related impacts to the biophysical environment, and the use of climate information on decision making. Uncertainty is introduced in each step of the climate planning-an-response process--in the scenarios used to drive the climate models, the information used to construct the models, and the interpretation and use of the model' data for planning and decision making (Figure 19.1). There are server key challenge, drawn from recommendations of the authors of this report, that contribute to these uncertainties in the Southwest: - There is a dearth of climate observations at high elevations and on the lands of Native nations.

  11. Energy. Chapter 4; Energia. Capitulo 4

    Energy Technology Data Exchange (ETDEWEB)

    Martin del Castillo, Carlos [Universidad Nacional Autonoma de Mexico, Mexico, D.F. (Mexico)

    2009-07-01

    This chapter stands out that the infrastructure for the electric energy generation, as well as the one departing from fossil fuels has been the responsibility of two institutions with great solvency in the scope of engineering: the Comision Federal de Electricidad (CFE) and Petroleos Mexicanos (PEMEX). It is presented here the energy future in a sustainable context; a prospective study to year 2050; a strategic proposal of Petroleos Mexicanos; the forecast of the oil industry in Mexico and a technological prospective of the energy. [Spanish] En este capitulo se destaca que la infraestructura para la generacion de energia, tanto electrica como a partir de combustibles fisiles ha corrido a cargo de dos instituciones con gran solvencia en el ambito de la ingenieria: la Comision Federal de Electricidad (CFE) y Petroleos Mexicanos (Pemex). Se presenta el futuro de la energia en un contexto sustentable; un estudio prospectivo al ano 2050; una propuesta estrategica de Petroleos Mexicanos; la prospectiva de la industria petrolera en Mexico y; una prospectiva tecnologica de la energia.

  12. Gaia DR1 documentation Chapter 6: Variability

    Science.gov (United States)

    Eyer, L.; Rimoldini, L.; Guy, L.; Holl, B.; Clementini, G.; Cuypers, J.; Mowlavi, N.; Lecoeur-Taïbi, I.; De Ridder, J.; Charnas, J.; Nienartowicz, K.

    2017-12-01

    This chapter describes the photometric variability processing of the Gaia DR1 data. Coordination Unit 7 is responsible for the variability analysis of over a billion celestial sources. In particular the definition, design, development, validation and provision of a software package for the data processing of photometrically variable objects. Data Processing Centre Geneva (DPCG) responsibilities cover all issues related to the computational part of the CU7 analysis. These span: hardware provisioning, including selection, deployment and optimisation of suitable hardware, choosing and developing software architecture, defining data and scientific workflows as well as operational activities such as configuration management, data import, time series reconstruction, storage and processing handling, visualisation and data export. CU7/DPCG is also responsible for interaction with other DPCs and CUs, software and programming training for the CU7 members, scientific software quality control and management of software and data lifecycle. Details about the specific data treatment steps of the Gaia DR1 data products are found in Eyer et al. (2017) and are not repeated here. The variability content of the Gaia DR1 focusses on a subsample of Cepheids and RR Lyrae stars around the South ecliptic pole, showcasing the performance of the Gaia photometry with respect to variable objects.

  13. Seguimiento del paciente asmático: qué debe saber el farmacéutico comunitario

    Directory of Open Access Journals (Sweden)

    Plaza Zamora J

    2013-03-01

    Full Text Available El asma tiene una prevalencia de entre un 1 y un 18% dependiendo del país. En el proceso de atención al paciente, y a través de los síntomas que presenta (disnea, tos, sibilancias, opresión torácica, el farmacéutico comunitario puede hacer educación sanitaria para evitar los agentes causales del asma, sobre cómo usar el dispositivo de inhalación prescrito por el médico, explicar al paciente su medicación, cómo es su tratamiento para conocer mejor su enfermedad, qué signos y síntomas denotan una falta de control de la misma, qué métodos se pueden usar para monitorizar la evolución del asma, detectar una posible falta de efectividad del tratamiento por tener sintomatología a pesar de estar usando adecuadamente el dispositivo de inhalación, sospechar que exista algún medicamento causante del asma, repasar el resto de medicación que usa por si existieran interacciones que afectaran tanto a la efectividad como a la seguridad del tratamiento. Existe un importante infradiagnóstico del asma, un 57,5% según el ECRHS (siglas del inglés European Community Respiratory Health Survey. En la farmacia comunitaria se puede hacer cribado de la enfermedad con la ayuda de cuestionarios validados en niños y no validados en adultos. Mediante la presente revisión se pretende ofrecer al farmacéutico comunitario una herramienta práctica para su labor diaria de atención al paciente asmático.

  14. Maduración sexual en una muestra de niños asmáticos

    Directory of Open Access Journals (Sweden)

    Gladys Abreu Suárez

    1996-04-01

    Full Text Available Con el objetivo de evaluar la repercusión del asma bronquial sobre la maduración sexual, se estudiaron en un corte transversal 180 niños asmáticos de uno y otro sexos, entre 7 y 15 años de edad, procedentes de la consulta externa del Hospital Pediátrico Docente de Centro Habana. A todos los niños se les evaluó el peso, la talla, los pliegues grasos y la maduración sexual y esquelética. Las medias de peso, talla y pliegues grasos se correspondieron con valores reportados en niños sanos. No se encontró retardo en la maduración sexual; la mayoría de los niños con estadios puberales avanzados se agruparon en los canales más altos de edad ósea.With the aim of assessing the effects of bronchial asthma on sex maturation, a cross-sectional study was carried out in 180 asthmatic children of both sexes, between 7 and 15 years old, outpatients coming from the Educational Pediatric Hospital at Centro Habana. An evaluation was made to all the children, and it included body weight, body height, skinfold thickness, bone development and sex maturation. Means in weight, height, and skinfold thickness were correspondent with the values reported for healthy children. No retardation was found in sex maturation; most part of the children with advanced pubertal stages were gathered in the highest channels of skeletal age.

  15. Chapter 2: Optical Properties of the Water Column

    Science.gov (United States)

    Kiefer, D. A.; Collins, D. J.

    1994-01-01

    In this chapter, and in chapter 29, the basic inter-relationship between the flux of radiant energy through the water column and the fixation of carbon by the phytoplankton in the ocean through processes of photosynthesis or primary production will be discussed.

  16. DCAA Contract Audit Manual. Volume 1, Chapters 1 - 11

    Science.gov (United States)

    1995-01-01

    basis. A contractor choos - counting period will be computed as ing to estimate the total cost of all described above. employees in the plan may use...the report should conform to Contractors should be encouraged to sub- Chapter 10. A i ICAA Coutract Audit Manul Jimmy 199 10(1) CHAPTER 10 NOTICE

  17. Chapter 1. Radioecology as a special part of ecology

    International Nuclear Information System (INIS)

    Toelgyessy, J.; Harangozo, M.

    2000-01-01

    This is a chapter of textbook of radioecology for university students. In this chapter authors deal with ecology and ecology terminology as well as its particular part - radioecology and it basic terminology. Connection of radioecology with other scientific and technical disciplines is reviewed

  18. Chapter 5. Using Habitat Models for Habitat Mapping and Monitoring

    Science.gov (United States)

    Samuel A. Cushman; Timothy J. Mersmann; Gretchen G. Moisen; Kevin S. McKelvey; Christina D. Vojta

    2013-01-01

    This chapter provides guidance for applying existing habitat models to map and monitor wildlife habitat. Chapter 2 addresses the use of conceptual models to create a solid foundation for selecting habitat attributes to monitor and to translate these attributes into quantifiable and reportable monitoring measures. Most wildlife species, however, require a complex suite...

  19. Implications of fire management on cultural resources [Chapter 9

    Science.gov (United States)

    Rebecca S. Timmons; Leonard deBano; Kevin C. Ryan

    2012-01-01

    Previous chapters in this synthesis have identified the important fuel, weather, and fire relationships associated with damage to cultural resources (CR). They have also identified the types of effects commonly encountered in various fire situations and provided some guidance on how to recognize damages and minimize their occurrence. This chapter describes planning...

  20. Colour Metallography of Cast Iron - Chapter 2: Grey Iron (Ⅲ

    Directory of Open Access Journals (Sweden)

    Zhou Jiyang

    2009-11-01

    Full Text Available The book, Colour Metallography of Cast Iron , uses colour metallography technique to study solidification structures of cast irons: graphite, carbides, austenite and eutectics; and focuses on solidification processes. With progress of modern solidification theory, the control of material solidification process becomes important measure for improving traditional materials and developing new materials. Solidification structure not only influences mechanical and physical properties of cast iron, but also affects its internal quality. The book uses a large amount of colour photos to describe the formation of solidification structures and their relations. Crystallization phenomena, which cannot be displayed with traditional metallography, are presented and more phase transformation information is obtained from these colour metallographic photos. This book consists of five sections: Chapter 1 Introduction, Chapter 2 Grey Iron, Chapter 3 Ductile Iron, Chapter 4 Vermicular Cast Iron, and Chapter 5 White Cast Iron. CHINA FOUNDRY publishs this book in several parts serially,starting from the first issue of 2009.

  1. Introduction to MODIS Cloud Products. Chapter 5

    Science.gov (United States)

    Baum, Bryan A.; Platnick, Steven

    2006-01-01

    derived from heritage instruments. This chapter provides an overview of the MODIS Level-2 and -3 operational cloud products.

  2. Education and Training of Radiotherapists. Chapter 17

    International Nuclear Information System (INIS)

    Coffey, M.

    2017-01-01

    The radiotherapist (RTT) is a member of the multidisciplinary team responsible for the preparation and delivery of a course of radiotherapy to cancer patients. The roles and responsibilities of the RTT vary significantly among countries and, in some instances, within countries. They are a reflection of both the local or broader national factors and the available resources, but must always incorporate accurate and safe practice. Irrespective of the scope of practice, roles and responsibilities, any educational programme developed for this professional group must not only prepare the RTTs for current practice, but enable them to adapt to future developments and challenges. Quality and equality of care for all patients receiving radiotherapy are the ultimate goals. To achieve these goals, educational programmes must include the subjects underpinning accurate and safe practice and must integrate academic and clinical components. Health care is undergoing reform in many countries, with a much stronger emphasis on patient centred care. However, reform of the delivery and quality of health care cannot be achieved without the parallel reform in health professional education. This need for reform is emphasized in the report on health professions education issued by the Institute of Medicine of the National Academies, wherein it is stated that “all health professionals should be educated to deliver patient-centered care as members of an interdisciplinary team, emphasizing evidence-based practice, quality improvement approaches, and informatics” [17.1]. This chapter deals with health care education in the United States of America, but the sentiment is equally applicable to the delivery of high quality health care for cancer patients throughout the world.

  3. Polysaccharides: Origin, Source and Properties. Chapter 2

    International Nuclear Information System (INIS)

    Al-Assaf, S.

    2016-01-01

    Polysaccharides are natural polymers that can be extracted from various sources. They can be extracted from plant cell walls (such as pectin, cellulose and starch); from seeds (guar gum (GG), locust bean gum (LBG) and tara gum (TG)); from tubers or roots (konjac mannan); and from seaweed (alginate and agarm carrageenan). In some cases, the source is tree exudates (gum arabic (GA), ghatti gum and karaya gum) or animals (hyaluronan, chitosan and chondroitin sulphate). Some types of bacteria and fungi are also a source of polysaccharides (xanthan, gellan, wellan, dextran, pullulan and cellulose). In their natural environment, polysaccharides provide structural support, gelation, hydration and lubrication, and play a role in cell signalling. They are commonly referred to as hydrocolloids, particularly in the food industry, but this term also includes proteins. Owing to their remarkable properties, polysaccharides are currently used as thickening, stabilizing, gelling, film forming and emulsifying agents in various industrial sectors. Furthermore, the quest to understand how they function in their natural assembly, whether as part of a cell wall or in connective tissues, has led to their use as a source of dietary fibre, as a therapeutic agent to restore lubrication in diseased osteoarthritic joints, as plant growth promoters and in anti-ageing applications, among others; they may find many more applications in the future. This chapter will explore the origins, molecular structures and conformations of natural polymers, with an emphasis on functionality. Also, methods employed for the modification of polysaccharides to enhance their functionality or produce novel materials, as well as those using radiation processing, will be briefly mentioned.

  4. Ecological consequences of manipulative parasites: chapter 9

    Science.gov (United States)

    Lafferty, Kevin D.; Kuris, A. M.

    2012-01-01

    phrases such as “may ultimately infl uence community structure” (Kiesecker and Blaustein 1999), yet few demonstrate ecological effects. Here, we consider the conditions under which manipulative parasites might have a substantial ecological effect in nature and highlight those for which evidence exists (see also Chapter 10).

  5. Getting the Most from Pi Sigma Alpha Chapters: Exploring the Chapter Activity Grant Program and Its Multiplier Effects

    Science.gov (United States)

    Alexander, Robert M.

    2009-01-01

    The political science honor society, Pi Sigma Alpha, has chapters in nearly 700 institutions across the United States. The organization sponsors many programs that can contribute a great deal to students of political science; however, many students are unaware of these opportunities. This article encourages chapter advisors to make use of these…

  6. Mundialización, acción colectiva e iniciativa local en la reconversión de Montreal

    Directory of Open Access Journals (Sweden)

    Juan-Luis Klein

    2003-05-01

    Full Text Available Este texto presenta un análisis del rol que juegan las iniciativas locales de base comunitaria en los procesos de desarrollo local, en el marco de la reconversión de las economías metropolitanas impulsada por la mundialización. La reconversión lleva a las metrópolis a especializarse en sectores económicos de alto tenor científico-técnico. Esto pone en peligro la viabilidad de los sectores más tradicionales, y sobre todo, fragiliza a la dotación de los espacios intrametropolitanos (municipios, distritos, barrios en los cuales estos sectores se habían especializado, en tanto que medios de vida y de trabajo. A partir del caso de Montreal, se verá que en estos espacios tienen lugar experiencias alternativas cuyo objetivo es el de conectar a las colectividades excluidas de la reconversión que se experimenta en los sectores de alta tecnología, la cual es impulsada por las fuerzas del mercado. Esto auspicia una vía de reconversión más incluyente desde el punto de vista social, en la cual la innovación tecnológica se combina con la innovación social. Pero también muestra que esta asociatividad es el resultado de un proceso en el cual las iniciativas locales, a través de acciones colectivas, estructuran el territorio, delimitan espacios de identidad y construyen las bases de un modelo de desarrollo en el cual lo económico se inserta en lo social, y en el cual el medio territorial se construye progresivamente.This text presents an analysis of the role played by communitarian based local initiatives in the process of local development, within the frame of the metropolitan economic reconversion driven by globalization. Reconversion makes metropolis specialize in high economic sectors, both technically and scientifically developed. This fact puts in danger the viability of the more traditional sectors and overall, fragilizes the endowment of intrametropolitan spaces (municipalities, districts, neighbourhoods in wich those sectores had

  7. Modeling vehicle operating speed on urban roads in Montreal: a panel mixed ordered probit fractional split model.

    Science.gov (United States)

    Eluru, Naveen; Chakour, Vincent; Chamberlain, Morgan; Miranda-Moreno, Luis F

    2013-10-01

    Vehicle operating speed measured on roadways is a critical component for a host of analysis in the transportation field including transportation safety, traffic flow modeling, roadway geometric design, vehicle emissions modeling, and road user route decisions. The current research effort contributes to the literature on examining vehicle speed on urban roads methodologically and substantively. In terms of methodology, we formulate a new econometric model framework for examining speed profiles. The proposed model is an ordered response formulation of a fractional split model. The ordered nature of the speed variable allows us to propose an ordered variant of the fractional split model in the literature. The proposed formulation allows us to model the proportion of vehicles traveling in each speed interval for the entire segment of roadway. We extend the model to allow the influence of exogenous variables to vary across the population. Further, we develop a panel mixed version of the fractional split model to account for the influence of site-specific unobserved effects. The paper contributes substantively by estimating the proposed model using a unique dataset from Montreal consisting of weekly speed data (collected in hourly intervals) for about 50 local roads and 70 arterial roads. We estimate separate models for local roads and arterial roads. The model estimation exercise considers a whole host of variables including geometric design attributes, roadway attributes, traffic characteristics and environmental factors. The model results highlight the role of various street characteristics including number of lanes, presence of parking, presence of sidewalks, vertical grade, and bicycle route on vehicle speed proportions. The results also highlight the presence of site-specific unobserved effects influencing the speed distribution. The parameters from the modeling exercise are validated using a hold-out sample not considered for model estimation. The results indicate

  8. Montreal Cognitive Assessment for screening mild cognitive impairment: variations in test performance and scores by education in Singapore.

    Science.gov (United States)

    Ng, Tze Pin; Feng, Lei; Lim, Wee Shiong; Chong, Mei Sian; Lee, Tih Shih; Yap, Keng Bee; Tsoi, Tung; Liew, Tau Ming; Gao, Qi; Collinson, Simon; Kandiah, Nagaendran; Yap, Philip

    2015-01-01

    The Montreal Cognitive Assessment (MoCA) was developed as a screening instrument for mild cognitive impairment (MCI). We evaluated the MoCA's test performance by educational groups among older Singaporean Chinese adults. The MoCA and Mini-Mental State Examination (MMSE) were evaluated in two independent studies (clinic-based sample and community-based sample) of MCI and normal cognition (NC) controls, using receiver operating characteristic curve analyses: area under the curve (AUC), sensitivity (Sn), and specificity (Sp). The MoCA modestly discriminated MCI from NC in both study samples (AUC = 0.63 and 0.65): Sn = 0.64 and Sp = 0.36 at a cut-off of 28/29 in the clinic-based sample, and Sn = 0.65 and Sp = 0.55 at a cut-off of 22/23 in the community-based sample. The MoCA's test performance was least satisfactory in the highest (>6 years) education group: AUC = 0.50 (p = 0.98), Sn = 0.54, and Sp = 0.51 at a cut-off of 27/28. Overall, the MoCA's test performance was not better than that of the MMSE. In multivariate analyses controlling for age and gender, MCI diagnosis was associated with a education was associated with a 3- to 5-point decrement (η(2) = 0.115 and η(2) = 0.162, respectively). The MoCA's ability to discriminate MCI from NC was modest in this Chinese population, because it was far more sensitive to the effect of education than MCI diagnosis. © 2015 S. Karger AG, Basel.

  9. Statistical modeling of the spatial variability of environmental noise levels in Montreal, Canada, using noise measurements and land use characteristics.

    Science.gov (United States)

    Ragettli, Martina S; Goudreau, Sophie; Plante, Céline; Fournier, Michel; Hatzopoulou, Marianne; Perron, Stéphane; Smargiassi, Audrey

    2016-11-01

    The availability of noise maps to assess exposure to noise is often limited, especially in North American cities. We developed land use regression (LUR) models for LA eq24h , L night , and L den to assess the long-term spatial variability of environmental noise levels in Montreal, Canada, considering various transportation noise sources (road, rail, and air). To explore the effects of sampling duration, we compared our LA eq24h levels that were computed over at least five complete contiguous days of measurements to shorter sampling periods (20 min and 24 h). LUR models were built with General Additive Models using continuous 2-min noise measurements from 204 sites. Model performance (adjusted R 2 ) was 0.68, 0.59, and 0.69 for LA eq24h , L night , and L den , respectively. Main predictors of measured noise levels were road-traffic and vegetation variables. Twenty-minute non-rush hour measurements corresponded well with LA eq24h levels computed over 5 days at road-traffic sites (bias: -0.7 dB(A)), but not at rail (-2.1 dB(A)) nor at air (-2.2 dB(A)) sites. Our study provides important insights into the spatial variation of environmental noise levels in a Canadian city. To assess long-term noise levels, sampling strategies should be stratified by noise sources and preferably should include 1 week of measurements at locations exposed to rail and aircraft noise.

  10. Social capital and obesity among adults: Longitudinal findings from the Montreal neighborhood networks and healthy aging panel.

    Science.gov (United States)

    Wu, Yun-Hsuan; Moore, Spencer; Dube, Laurette

    2017-11-29

    Curbing the worldwide increase in obesity requires upstream social interventions that modify the environment in which obesity emerges. Recent studies have suggested that social capital and networks may influence a person's risk of obesity. Yet, few longitudinal studies have assessed whether social capital and networks reduce obesity risk in adult populations. In this study, the data come from three waves (2008, 2010, and 2013) of the Montreal Neighborhood Networks and Health Aging Panel (N=2606). Self-reported height and weight were used to calculate body mass index (BMI) with obesity defined as a BMI>30. Name and position generator instruments captured network measures of social capital, including: (1) upper reachability, (2) range, (3) diversity and (4) the number of kin ties. Questions on generalized trust and participation were used to assess cognitive and structural dimensions of social capital. Separate random effects logistic regression was used to examine the association among social network characteristics, social capital, and obesity. We found the greater the number of kin ties in a person's network, the greater the risk of obesity (OR: 1.33, 95% CI: 1.08-1.62). Adults with higher network diversity (OR: 0.83, 95% CI: 0.72-0.96) and high generalized trust (OR: 0.52, 95% CI: 0.35-0.77) were at a lower the risk of obesity. The current study confirmed that higher network capital and trust were protective against obesity, while having kin ties was not. Disentangling the multidimensional role that social capital plays can lead to more effective interventions to reduce obesity. Copyright © 2017 Elsevier Inc. All rights reserved.

  11. Comparison of montreal cognitive assessment and mini-mental state examination in evaluating cognitive domain deficit following aneurysmal subarachnoid haemorrhage.

    Directory of Open Access Journals (Sweden)

    George Kwok Chu Wong

    Full Text Available Cognitive deficits are common after aneurysmal subarachnoid haemorrhage (aSAH, and clinical evaluation is important for their management. Our hypothesis was that the Montreal Cognitive Assessment (MoCa is superior to the Mini-Mental State Examination (MMSE in screening for cognitive domain deficit in aSAH patients.We carried out a prospective observational and diagnostic accuracy study on Hong Kong aSAH patients aged 21 to 75 years who had been admitted within 96 hours of ictus. The domain-specific neuropsychological assessment battery, the MoCA and MMSE were administered 2-4 weeks and 1 year after ictus. A cognitive domain deficit was defined as a cognitive domain z score <-1.65 (below the fifth percentile. Cognitive impairment was defined as two or more cognitive domain deficits. The study is registered at ClinicalTrials.gov of the US National Institutes of Health (NCT01038193.Both the MoCA and the MMSE were successful in differentiating between patients with and without cognitive domain deficits and cognitive impairment at both assessment periods. At 1 year post-ictus, the MoCA produced higher area under the curve scores for cognitive impairment than the MMSE (MoCA, 0.92; 95% CI, 0.83 to 0.97 versus MMSE, 0.77; 95% CI, 0.66 to 0.83, p = 0.009.Cognitive domain deficits and cognitive impairment in patients with aSAH can be screened with the MoCA in both the subacute and chronic phases.

  12. "I love having benzos after my coke shot": The use of psychotropic medication among cocaine users in downtown Montreal.

    Science.gov (United States)

    Motta-Ochoa, Rossio; Bertrand, Karine; Arruda, Nelson; Jutras-Aswad, Didier; Roy, Élise

    2017-11-01

    Cocaine abuse is a major public health issue due to its role in the HIV and hepatitis C virus (HCV) epidemics in North America. A significant area of concern among people who use cocaine (PWUC), injected or smoked, is their frequent misuse of prescription drugs, particularly psychotropic medication (PM), such as tranquilizers, sedatives, stimulants, and antipsychotics. This paper aims to describe and understand practices of PM use among PWUC in downtown Montreal. Ethnographic methods including participant observation and semi-structured interviews were used in an iterative manner. Two thirds of the 50 participants were male. They ranged in age from 20 to 60 and most were homeless. A significant proportion of them reported polydrug use patterns that included frequent concomitant opioid use (heroin and/or prescription opioids (PO)). Benzodiazepine-based tranquilizers and the atypical antipsychotic quetiapine were the most frequently used PM. Routes of PM administration were oral, nasal and, to a lesser degree, intravenous. Five main PM use practices were identified: 1) "downers" from cocaine high (benzodiazepines and quetiapine); 2) enhancers of heroin/PO effects (benzodiazepines); 3) reducers or suppressors of heroin/PO withdrawal symptoms (benzodiazepines); 4) enablers of a different type of "trip" (benzodiazepines); and 5) treatment for mental and physical problems (benzodiazepines and quetiapine). PM use practices showed several complementary functions that PM fulfill in a context of polydrug use. The soothing and stimulating effects of PM reinforce the patterns of drug use among participants, posing various risks including overdose, HIV/HCV transmission, PM dependence and accidents. The results highlight the need for clinicians to assess clients' substance use patterns when prescribing PM and to question PWUC about PM use. The findings also underline certain unmet service needs in relation to overdose, HIV/HCV and mental health prevention/treatment among cocaine

  13. Risk factor modifications and depression incidence: a 4-year longitudinal Canadian cohort of the Montreal Catchment Area Study

    Science.gov (United States)

    Meng, Xiangfei; Brunet, Alain; Turecki, Gustavo; Liu, Aihua; D'Arcy, Carl; Caron, Jean

    2017-01-01

    Objective Few studies have examined the effect of risk factor modifications on depression incidence. This study was to explore psychosocial risk factors for depression and quantify the effect of risk factor modifications on depression incidence in a large-scale, longitudinal population-based study. Methods Data were from the Montreal Longitudinal Catchment Area study (N=2433). Multivariate modified Poisson regression was used to estimate relative risk (RR). Population attributable fractions were also used to estimate the potential impact of risk factor modifications on depression incidence. Results The cumulative incidence rate of major depressive disorder at the 2-year follow-up was 4.8%, and 6.6% at the 4-year follow-up. Being a younger adult, female, widowed, separated or divorced, Caucasian, poor, occasional drinker, having a family history of mental health problems, having less education and living in areas with higher unemployment rates and higher proportions of visible minorities, more cultural community centres and community organisations, were consistently associated with the increased risk of incident major depressive disorder. Although only 5.1% of the disease incidence was potentially attributable to occasional drinking (vs abstainers) at the 2-year follow-up, the attribution of occasional drinking doubled at the 4-year follow-up. A 10% reduction in the prevalence of occasional drinking in this population could potentially prevent half of incident cases. Conclusions Modifiable risk factors, both individual and societal, could be the targets for public depression prevention programmes. These programmes should also be gender-specific, as different risk factors have been identified for men and women. Public health preventions at individual levels could focus on the better management of occasional drinking, as it explained around 5%~10% of incident major depressive disorders. Neighbourhood characteristics could also be the target for public prevention

  14. Quick screening of cognitive function in Indian multiple sclerosis patients using Montreal cognitive assessment test-short version

    Directory of Open Access Journals (Sweden)

    Darshpreet Kaur

    2013-01-01

    Full Text Available Background: Cognitive impairments in multiple sclerosis (MS are now well recognized worldwide, but unfortunately this domain has been less explored in India due to many undermining factors. The aim of this study was to evaluate cognitive impairments in Indian MS patients with visual or upper limb motor problems with the help of short version of Montreal cognitive assessment test (MoCA. Subjects and Methods: Thirty MS patients and 50 matched controls were recruited for the 12 points MoCA task. Receiver operating characteristic curve (ROC analysis was performed to determine optimal sensitivity and specificity of the 12 points MoCA in differentiating cognitively impaired patients and controls. Results: The mean 12 points MoCA scores of the controls and MS patients were 11.56 ± 0.67 and 8.06 ± 1.99, respectively. In our study, the optimal cut-off value for 12 points MoCA to be able to differentiate patients with cognitive impairments from controls is 10/12. Accordingly, 73.3% patients fell below the cut off value. Both the groups did not have significant statistical differences with regard to age and educational years. Conclusion: The 12 points, short version of MoCA, is a useful brief screening tool for quick and early detection of mild cognitive impairments in subjects with MS. It can be administered to patients having visual and motor problems. It is of potential use by primary care physicians, nurses, and other allied health professionals who need a quick screening test. No formal training for administration is required. Financial and time constraints should not limit the use of the proposed instrument.

  15. Comparing the clinical presentation of first-episode psychosis across different migrant and ethnic minority groups in Montreal, Quebec.

    Science.gov (United States)

    van der Ven, Elsje; Bourque, François; Joober, Ridha; Selten, Jean-Paul; Malla, Ashok K

    2012-05-01

    To explore differences in severity and nature of symptoms of first-episode psychosis (FEP) according to ethnic group and migrant status. We administered rating scales to assess positive and negative symptoms, as well as general psychopathology, to 301 consecutive patients presenting with an FEP within a defined catchment area in Montreal, Quebec, classified according to ethnicity and migrant status. Symptom scores of Euro-Canadian patients without a recent history of migration, that is, the reference group (n = 145), were compared with those of African and Afro-Caribbean (n = 39), Asian (n = 27), Central and South American (n = 15), Middle Eastern and North African (n = 24), and European and North American (n = 39) patients. Except for referral source, there were no significant differences between ethnic groups on any demographic variables. The African and Afro-Caribbean group had a higher level of negative symptoms (especially alogia) and general psychopathology scores on the Positive and Negative Syndrome Scale (especially, uncooperativeness, preoccupation, and poor attention), compared with the reference group. Ethnic groups did not differ on the Scale for the Assessment of Positive Symptoms scores. A comparison of FEP patients from different ethnic groups and native-born Euro-Canadians revealed no significant differences in the nature of positive symptoms at first presentation or in age at onset, suggesting that there was no evidence for the hypothesis that ethnic minorities are misdiagnosed as psychotic. Increased severity of negative symptoms and general psychopathology, specifically among the black ethnic minority group, may have implications for the role of ethnicity for the treatment and outcome of the initial episode of psychotic disorders.

  16. Seville City Hall Chapter Room ceiling decoration

    Directory of Open Access Journals (Sweden)

    Robador, M. D.

    2010-02-01

    Full Text Available The present article describes a chemical and physical study of the colour, chemical composition and mineral phases of the decorative materials in the Seville City Hall Chapter House ceiling. The findings showed that the inner most layer of material, calcite, was covered with white lead, in turn concealed under a layer of gilded bole. The ceiling underwent re-gilding, also over bole, due in all likelihood to wear on the original gold leaf. In the nineteenth century, the entire ceiling with the exception of the inscriptions was whitewashed with calcite and white lead. Silver was employed on King John I’s sword (coffer 27. Gold leaf was used to adorn the royal attributes: crowns, belts, sceptres, swords and rosary beads. The high reliefs were likewise gilded. The pigments identified on the ceiling adornments included azurite, malachite, vermilion and gas black. A lime and ground dolomite mortar was used throughout.

    El objetivo de este trabajo es el estudio de diferentes aspectos, como el color, la composición química y las fases mineralógicas presentes en los diferentes materiales que forman la ornamentación del techo de la Sala Capitular del Ayuntamiento de Sevilla, mediante métodos físicos y químicos. Nuestros resultados muestran que el dorado fue realizado sobre una capa de bol previamente depositada sobre una lámina de blanco de plomo que cubría un estrato de calcita. Posteriormente, y probablemente debido a alteraciones en el dorado original, el techo fue de nuevo dorado usando una técnica similar. En el siglo XIX, casi todo el techo, excepto las zonas con inscripciones, fue blanqueado usando una mezcla de calcita y blanco de plomo. Se empleó plata para cubrir la espada del rey Juan I (casetón 27. Finísimas láminas de oro se usaron para decorar los atributos reales: coronas, cinturones, cetros, espadas y rosarios. En diferentes partes de la decoración fueron detectados pigmentos como azurita, malaquita, bermellón y

  17. A avaliação da Qualidade de Vida no Doente Asmático

    Directory of Open Access Journals (Sweden)

    C.H. Leroyer

    1998-11-01

    Full Text Available RESUMO: A avaliarção da Qualidade de Vida (QV do doente respiratório crónico, tem suscitado um interesse cresceote nos últimos anos. O conceito de QV é complexo, sendo, segundo o grupo de trabalho da OMS sobre este tema: “… influenciado pelo estado de saúde fisico, psicológico, o grau de independência, a inserrção social e as relarções com os constituintes essenciais do meio ambiente”. Neste trabalho, os autores abordam a importância e o lugar da avaliação da QV no estudo do doente com asma brônquica e analisam OS diferéntes métodos de avaliação disponíveis.Tal como as outras doenças respiratórias crónicas, a asma tem repercussões na qualidade de vida dos doentes. Como resposta, o.doente asmàtico pode desenvolver mecanismos de adaptação complexos, ex: diminuir o seu nível de actividade funcional (fenómeno de “normalidade ajustada” em que ao fim de certo tempo, a incapacidade para a realização de certas actividades fisicas é assumido pelo doente como “normal”. A avaliação da qualidade de vida deve, nestes casos, ser capaz de evidenciar a real limitação da actividade do doente.Os factores exteriores (ex: elirna, também exercem uma influência determinante sobre o doente asmátìco. Em resposta a estes, o doente pode limitar a sua actividadc (ex: evitar ambientcs enfumarados ou evitar o exercicio ao ar livre nos dias frios ou pode alterar o meio ambientc (ex: medidas de evicção dos ácaros.A asma brônquica afecta três domínios da vida do indivíduo: Físico, Psíquico e Social. Como resultado, a avaliarção da QV do doente asmático é um estudo pluridimensional e deve ser encarada como complementar dos restantes indicadores habitualmente empregues no estudo da asma (estudo funcional respiratório, análiscs, “scores” clinicos, etc.. Além disso

  18. A practical example of code comparison evaluation of conformance to the Asme 3 code of large nuclear replacement parts manufactured according to RCC-M

    International Nuclear Information System (INIS)

    Dunand-Roux, L.; Berger, T.; Grandemange, J.M.; Lemoine, M.

    2004-01-01

    This paper summarizes the work carried out to evaluate the compliance of a French RCC-M practice with the ASME Code, for installation of pressurized water reactor closure heads manufactured as per the French regulations, on American nuclear power plants. This evaluation covers all requirements regarding: - Materials and purchases, - Design and analysis, - Manufacturing, welding and related qualifications, - Non-destructive inspections. On completion of this evaluation, a number of additional justifications were produced, revealing that the technical solutions retained are compatible with both construction codes. (authors)

  19. Report on the activities of the ASME-NQA Committee Working Group on Quality Assurance Requirements for Research and Development, April 1990 to August 1991

    Energy Technology Data Exchange (ETDEWEB)

    Dronkers, J.J.

    1991-09-01

    This report transmits to the public eye the activities of the American Society of Mechanical Engineers-Nuclear Quality Assurance (ASME-NQA) Committee Working Group on Quality Assurance Requirements for Research and Development. The appendix lists the members of this group as of August 1991. The report covers a period of 17 months. The working group met eight times in this period, and much intellectual ground was traversed. There was seldom agreement on the nature of the task, but there was no doubt as to its urgency. The task was how to adapt the nuclear quality assurance standard, the NQA-1, to research and development work. 1 fig., 7 tabs.

  20. Função respiratória em filhos de mães asmáticas

    Directory of Open Access Journals (Sweden)

    Marco A. Valadares

    2013-04-01

    Full Text Available OBJETIVO: Avaliar a função pulmonar e as manifestações clínicas sugestivas de asma em filhos de mães com diagnóstico médico referido de asma. MÉTODOS: Estudo observacional transversal analítico aninhado a uma coorte de 4.757 parturientes. Foram avaliadas 86 crianças aos seis anos de idade, filhas de mães com diagnóstico médico de asma antes da gestação. Foram coletadas informações referentes a sintomatologias clínicas de atopias e doenças respiratórias, variáveis socioeconômicas e de exposição; tendo sido as crianças submetidas à espirometria. RESULTADOS: Foram encontrados 30,3% de alterações espirométricas, havendo predomínio do diagnóstico de asma nos que apresentaram padrão obstrutivo. Diagnóstico médico pregresso de asma ocorreu em 9,3% das crianças; contudo, o diagnóstico estabelecido a partir da presença e frequência dos sintomas de asma representou 18,6%. Das 86 crianças participantes, 37,2% tiveram um escore de cinco ou mais pontos no questionário ISAAC, estando isso associado à alteração do padrão espirométrico (p = 0,002. Após a regressão logística múltipla, maior escolaridade paterna, maior número de quartos no domicílio e o fato de a mãe não ter apresentado "chiado" durante a gestação foram estatisticamente significantes como fatores protetores para a presença de distúrbio ventilatório à espirometria. CONCLUSÕES: A frequência de alterações do teste espirométrico em filhos de mães asmáticas foi alta, com o padrão restritivo ocorrendo mais vezes que o obstrutivo. Houve uma maior ocorrência de exames obstrutivos naqueles que apresentavam sintomatologia clínica de asma, com uma frequência de diagnóstico clínico de asma superior à encontrada na literatura.