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Sample records for argon beam coagulation

  1. The use of argon beam coagulation in pressure sore reconstruction.

    Science.gov (United States)

    Buck, Donald W; Lewis, Victor L

    2009-12-01

    Pressure sores are a significant source of physical and financial burden for debilitated patients. When conservative measures fail, surgical reconstruction with myocutaneous flaps may be the last hope for cure and/or improved quality of life in these patients. Adequate haemostasis is an integral component of these reconstructive procedures, as bleeding and haematoma formation can lead to increased morbidity. This study was designed to investigate the use of argon beam coagulation in patients undergoing bony debridement and subsequent pressure sore reconstruction with myocutaneous flaps. The clinical records of 34 patients undergoing pressure sore reconstruction with the use of argon beam coagulation from 2004 to 2006 at an academic institution were reviewed and outcomes were assessed. Reconstruction was performed by a single surgeon on 34 patients (31 men, three women; mean age 41+/-15 years), with a total of 41 pressure sores. Thirteen (32.5%) patients had evidence of osteomyelitis preoperatively and five (12.5%) had previous coccygectomies secondary to infection. Twenty-six (65%) of the pressure sores were treated with hamstring V-Y musculocutaneous flaps, 10 (25%) with gluteal flaps, and four (10%) with tensor fascia lata flaps. Overall, suture line dehiscence occurred in six (15%) cases, flap failure and pressure sore recurrence occurred in six (15%) cases, an abscess developed in one (2.5%) case, and a sinus tract with a superficial wound developed in one (2.5%) case. There were no complications related to haemostasis, including excessive bleeding or haematoma formation. Argon beam coagulation is an efficacious tool for achieving adequate haemostasis during pressure sore reconstruction, particularly when significant bony debridement is involved. The use of argon beam coagulation does not result in an increased complication or recurrence rate when compared with conventional electrocautery methods.

  2. Argon beam coagulation for treatment of symptomatic radiation-induced proctitis.

    Science.gov (United States)

    Fantin, A C; Binek, J; Suter, W R; Meyenberger, C

    1999-04-01

    Radiation proctitis is a complication of radiotherapy for malignant pelvic disease. Argon beam coagulation is a new and rapidly evolving technology that permits a "no-touch" electrocoagulation of diseased tissue. We analyzed retrospectively the records of 7 patients with prostatic and endometrial cancers treated with irrradiation (median radiation dose was 6840 cGy, range 2400 to 7200 cGy). The median time to onset of symptoms after the conclusion of radiotherapy was 20 months (range 16 to 48 months); symptoms consisted of rectal bleeding and tenesmus in all patients. The patients underwent argon beam coagulation after colonoscopic evaluation. The usual treatment interval was 3 weeks (range 1 to 3 weeks). A median of 2 treatment sessions (range 2 to 4) was necessary for complete symptom relief. All interventions were well tolerated without complications. During follow-up (median 24 months, range 18 to 24 months), there was no recurrence of symptoms (bleeding, tenesmus). Argon beam coagulation is a safe, well tolerated, and effective treatment option in symptomatic radiation proctitis.

  3. Argon plasma coagulation for treatment of hemorrhagic radiation gastroduodenitis

    Energy Technology Data Exchange (ETDEWEB)

    Maekawa, Shu-Ji; Aoyama, Nobuo; Shirasaka, Daisuke; Inoue, Takashi; Kuroda, Kohei; Ebara, Shigeyuki; Tamura, Takao; Miyamoto, Masaki; Kasuga, Masato [Kobe Univ. (Japan). Graduate School of Medicine

    2002-01-01

    A 79-year-old man who had received radiotherapy for portal vein thrombosis due to hepatocellular carcinoma (HCC) 5 months earlier, showed progressive anemia and melena. Endoscopy on admission revealed diffuse bleeding from multiple telangiectasias on the anterior wall of the antrum and bulbus. We treated this patient with a new non-contact hemostatic method: the argon plasma coagulator (APC). The melena stopped after the first session and the hemoglobin level remained stable for 7 months. No delayed complications have been observed. Gastrointestinal bleeding from chronic radiation gastroduodenitis is rarely reported compared with radiation proctitis. This case demonstrates that APC is effective for hemostasis of diffuse bleeding from radiation gastroduodenitis, just as for radiation protitis. (author)

  4. Bronchoscopic electrocauterization versus argon plasma coagulation as a palliative management for patients with bronchogenic carcinoma

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    Amgad A. Farhat

    2015-01-01

    It was concluded that, therapeutic bronchoscopic intervention either by electrocautery or argon plasma coagulation is a safe and effective method for palliative management of patients with central malignant airway obstruction.

  5. Ablation of Barrett’s esophagus using the second-generation argon plasma coagulation

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    Objective To investigate the efficacy and safety of the second-generation argon plasma coagulation (VIO APC) in ablation of Barrett’s esophagus. Methods Eighteen patients with Barrett’s esophagus (12 males, median age of 55 years, median length of 2.1 cm,1 low-grade dysplasia, 13 cases of short segment Barrett’s esophagus) received VIO APC, which was performed at a power setting of 40W and argon gas flow at 1.5-2.0 L/min, "forced" mode, in 1-3 sessions (mean 1.3). All the patients received treatment with hi...

  6. Epinephrine plus argon plasma or heater probe coagulation in ulcer bleeding

    Institute of Scientific and Technical Information of China (English)

    Ahmet Karaman; Mevlut Baskol; Sebnem Gursoy; Edip Torun; Alper Yurci; Banu Demet Ozel; Kadri Guven; Omer Ozbakir; Mehmet Yucesoy

    2011-01-01

    AIM: To compare the effectiveness of argon plasma coagulation (APC) and heater probe coagulation (HPC) in non-variceal upper gastrointestinal bleeding. METHODS: Eighty-five (18 female, 67 male) patients admitted for acute gastrointestinal bleeding due to gastric or duodenal ulcer were included in the study. Upper endoscopy was performed and HPC or APC were chosen randomly to stop the bleeding. Initial hemostasis and rebleeding rates were primary and secondary end-points of the study. RESULTS: Initial hemostasis was achieved in 97.7% (42/43) and 81% (36/42) of the APC and HPC groups, respectively (P 0.05). CONCLUSION: APC is an effective hemostatic method in bleeding peptic ulcers. Larger multicenter trials are necessary to confirm these results.

  7. Long-term outcomes of endoscopic argon plasma coagulation (APC) therapy for early esophageal cancer and precancerous lesions

    Institute of Scientific and Technical Information of China (English)

    王国清

    2013-01-01

    Objective To evaluate the long-term outcomes of endoscopic argon plasma coagulation (APC) therapy for early esophageal cancer and precancerous lesions.Methods One-hundred and seventy one cases with early esophageal cancer (intramucosal carcinoma) and precancerous lesions were treated by APC from 1994 to 2005,

  8. Ablation of Barrett's esophagus using the second-generation argon plasma coagulation

    Institute of Scientific and Technical Information of China (English)

    Li Zhang; Lei Dong; Jia Liu; Xiao-lan Lu

    2009-01-01

    Objective To investigate the efficacy and safety of the second-generation argon plasma coagulation (VIO APC) in ablation of Barrett's esophagus. Methods Eighteen patients with Barrett's esophagus (12 males, median age of 55 years, median length of 2.1 cm,1 low-grade dysplasia, 13 cases of short segment Barrett's esophagus) received VIO APC, which was performed at a power setting of 40W and argon gas flow at 1. 5-2. 0 L/min, "forced" mode, in 1-3 sessions (mean 1.3). All the patients received treatment with high-dose proton pump inhibitors. The main complaints before ablation were upper abdominal pain in 12 patients (66%), sour regurgitation in 14 patients (77%), and dysphagia or odynophagia in 7 patients (38%). Two patients (11%) had esophageal hiatal hernia. Results The percentage of patients in whom ablation was endoscopically achieved proximal to the gastroesophageal junction was 77. 8%(14/18), and histologically achieved in 66. 7% (12/18). Berried glands were observed in 2 patients who had achieved endoscopic ablation, the areas of Barrett's mucosa were reduced by more than 60% in the other 4 patients. After treatment, 4 patients had transient retrosternal pain and 3 patients had mild epigastric discomfort. One patient had small amounts of hemorrhage during the process, and it ceased after norepinephrine and thrombosin were administered through endoscope biopsy channel. No esophageal stricture or other severe adverse events was observed. During 11.8 (4-15) months' follow-up, the patients who had achieved the complete ablation had no evidence of relapse of Barrett's esophagus. Conclusion VIO APC with a relatively low power setting can effectively ablate the Barrett's mucosa with special intestinal metaplasia when standard APC has been done. No severe adverse events were observed. Long-term follow-up is needed to assess cancer prevention and the durability of the neo-squamous epithelium.

  9. Prophylactic argon plasma coagulation ablation does not decrease delayed postpolypectomy bleeding.

    Science.gov (United States)

    Lee, Chang Kyun; Lee, Suck-Ho; Park, Ji-Young; Lee, Tae Hoon; Chung, Il-Kwun; Park, Sang-Heum; Kim, Hong-Soo; Kim, Sun-Joo

    2009-08-01

    The most common complication of colonoscopic polypectomy is postpolypectomy bleeding (PPB). However, there are no established guidelines for the prevention of delayed PPB. It is possible that submucosal vessels of an artificial ulcer are a potential source of delayed bleeding that occurs several days after polypectomy. The aim of this randomized, controlled study was to evaluate the efficacy of prophylactic argon plasma coagulation (APC) of nonbleeding visible vessels in preventing delayed PPB. A prospective, randomized, controlled study. A tertiary referral center. A total of 987 polyps in 600 consecutive patients were resected by colonoscopic polypectomy. In patients who underwent APC (APC group), all nonbleeding visible vessels on the ulcer crater were targeted and were then coagulated by APC ablation until they disappeared, but not in patients who did not undergo APC (control group). The incidence of delayed PPB in the APC group was compared with that in the control group. Delayed PPB occurred in 3.3% (16/475) of all the patients, including 2.5% (6/240) in the APC group and 4.3% (10/235) in the control group. No significant differences were observed between the 2 groups in the rates of delayed PPB, irrespective of the type of delayed bleeding (significant bleeding: 0.8% [2/240] vs 1.3% [3/235], P = .638; minor bleeding: 1.7% [4/240] vs 3% [7/235], P = .378). There were no significant APC-related complications. Single-center study. Prophylactic APC ablation does not appear to have an additional advantage in the prevention of delayed PPB.

  10. Adrenaline Injection Plus Argon Plasma Coagulation versus Adrenaline Injection Plus Hemoclips for Treating High-Risk Bleeding Peptic Ulcers: A Prospective, Randomized Trial

    Directory of Open Access Journals (Sweden)

    Seyed Alireza Taghavi

    2009-01-01

    Full Text Available BACKGROUND/OBJECTIVE: Several combination endoscopic therapies are currently in use. The present study aimed to compare argon plasma coagulation (APC + adrenaline injection (AI with hemoclips + AI for the treatment of high-risk bleeding peptic ulcers.

  11. Converging of Argon Cluster Ion Beams with a Glass Capillary

    Science.gov (United States)

    Shoji, Kazuhiro; Iuchi, Kensuke; Izumi, Motoki; Moritani, Kousuke; Inui, Norio; Mochiji, Kozo

    We have investigated the converging behavior of argon gas cluster ion beam passed through a glass capillary. The gas cluster ions are attractive as a projectile for SIMS from the view point of minimization of the damages. The cluster ion beam of 5 keV consisting of 500˜3000 argon atoms was injected in the capillary. The inner diameters of the capillary at the inlet and outlet were 0.8 mm and 9.6˜140 μm, respectively. Ion current from the outlet of the all the capillaries were detected. We obtained the converging factor of 2˜7, which depended on the incident ion current. The kinetic energy of the incident ions was found to be reduced by 20˜30% by passing through the capillary. Contrary, the velocity of the ions was not changed. These facts suggest that the cluster becomes 20˜30% smaller in mass by passing through the capillary. As far as we know, this is the first report on the study of the converging of cluster ions by using a glass capillary.

  12. Temporal evolution of electron beam generated Argon plasma in pasotron device

    Science.gov (United States)

    Khandelwal, Neha; Pal, U. N.; Prakash, Ram; Choyal, Y.

    2016-10-01

    The plasma- assisted slow wave oscillator (PASOTRON) is a high power microwave source in which the electron beam in the interaction region is confined by the background plasma. The plasma is generated by impact ionization of background gas with the electron beam. A model has been developed for temporal evolution of Argon plasma in pasotron device. In this model, we consider electron beam of energy E interacting with Argon gas. The resulting ionization creates quasi neutral argon plasma composed of argon Ar atoms, singly ionized ions Ar+1and electrons having energy from 0 to E. Electron impact excitation, ionization, radiative decay, radiative recombination and three body recombination processes are considered in this model. Population of ground and excited states of argon atom, ground state of argon ion as well as the population of electron energy groups is calculated by solving time dependent rate equations. Temporal evolution of electron beam generated plasma is given.

  13. Long-term follow-up after complete ablation of Barrett's esophagus with argon plasma coagulation

    Institute of Scientific and Technical Information of China (English)

    Ahmed Madisch; Stephan Miehlke; Ekkehard Bayerd(o)rffer; Birgit Wiedemann; David Antos; Anke Sievert; Michael Vieth; Manfred Stolte; Heinrich Schulz

    2005-01-01

    AIM: To report the long-term outcome of patients after complete ablation of non-neoplastic Barrett's esophagus (BE) with respect to BE relapse and development of intraepithelial neoplasia or esophageal adenocarcinoma.METHODS: In 70 patients with histologically proven nonneoplastic BE, complete BE ablation was achieved by argon plasma coagulation (APC) and high-dose proton pump inhibitor therapy (120 mg omeprazole daily). Sixty-six patients (94.4%) underwent further surveillance endoscopy. At each surveillance endoscopy four-quadrant biopsies were taken from the neo-squamous epithelium at 2 cm intervals depending on the pre-treatment length of BE mucosa beginning at the neo-Z-line, and from any endoscopically suspicious lesion.RESULTS: The median follow-up of 66 patients was 51 mo (range 9-85 mo) giving a total of 280.5 patient years.A mean of 6 biopsies were taken during surveillance endoscopies. In 13 patients (19.7%) tongues or islands suspicious for BE were found during endoscopy. In 8 of these patients (12.1%) non-neoplastic BE relapse was confirmed histologically giving a histological relapse rate of 3% per year. In none of the patients, intraepithelial neoplasia nor an esophageal adenocarcinoma was detected.Logistic regression analysis identified endoscopic detection of islands or tongues as the only positive predictor of BE relapse (P = 0.0004).CONCLUSION: The long-term relapse rate of nonneoplastic BE following complete ablation with high-power APC is low (3% per year).

  14. Argon plasma coagulation of gastrojejunal anastomosis for weight regain after gastric bypass.

    Science.gov (United States)

    Baretta, Giorgio A P; Alhinho, Helga C A W; Matias, Jorge Eduardo F; Marchesini, João Batista; de Lima, João Henrique F; Empinotti, Celso; Campos, Josemberg M

    2015-01-01

    The failure of approximately 20 % of obese patients who undergo Roux-en-Y gastric bypass (RYGB) to maintain weight loss over the following 18-24 months is related to the surgical procedure, to the patient, or both. Although the underlying mechanisms are uncertain, one factor that has been postulated is the dilation of the gastrojejunal anastomosis. The objective was to evaluate the safety and efficacy of the serial use of argon plasma coagulation (APC) in reducing the diameter of the dilated gastrojejunal anastomosis and post-RYGB weight regain. We carried out a prospective, nonrandomized study of 30 patients, with no control or sham group, monitoring RYGB weight regain associated with dilation of the gastrojejunal anastomosis over a postoperative period of 18 months. Each patient underwent three sessions of APC in the anastomosis separated by 8 weeks, with a final endoscopic examination 8 weeks after the last session. There was a loss of 15.48 kg (range = 8.0-16.0 kg) of the 19.6 kg (range = 7.0-39.0 kg) of regained weight after RYGB and a reduction of 66.89 % in the final anastomotic diameter, with statistically significant reductions between each APC session. Previous body mass index significantly decreased up to the final examination, and the final weight was close to but not at the same level as the nadir. Our study indicates that the use of APC to treat weight regain after RYGB is a safe and effective procedure and promotes a reduction in gastrojejunal anastomosis, final weight, and BMI, with a low rate of complications.

  15. Video: argon plasma coagulator in a 2-month-old child with tracheoesophageal fistula.

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    Nardo, Giovanni Di; Oliva, Salvatore; Barbato, Maria; Aloi, Marina; Midulla, Fabio; Roggini, Mario; Valitutti, Francesco; Frediani, Simone; Cucchiara, Salvatore

    2012-09-01

    A 2 month-old boy was admitted to the authors' hospital because of regurgitation and persistent cough during breastfeeding. A chest X-ray examination and a barium esophagogram disclosed small amounts of barium passing in the trachea, suggesting a tracheoesophageal fistula (TEF). Bronchoscopy combined with upper gastrointestinal (GI) endoscopy performed with the patient under general anesthesia confirmed the fistula. The TEF was treated by injection of 1 ml Glubran 2 from the esophageal side. A nasogastric tube was placed for feedings, and 7 days later, a barium esophagogram showed a reduction of caliber but not complete closure of the TEF. Unsuccessful fistula obliteration with Glubran was attributed to technical difficulties in catheterization of the fistula orifice, mainly resulting from its close proximity to the upper esophageal sphincter and to its small caliber. Therefore, an argon plasma coagulator (APC) probe with a circumferentially oriented nozzle was used from the esophageal side as an alternative technique to fulgurate the residual fistula orifice (see video). A nasogastric tube was placed for feedings. Oral feeding was started 7 days later when a barium esophagogram confirmed complete fistula closure. At the 2-year follow-up visit, the boy was asymptomatic, and the barium esophagogram was negative. This report describes a case in which esophagoscopy gave a clear view of the fistula due to its direction from esophagus to trachea. Complete fistula obliteration was not obtained with Glubran. However, APC was successfully used to close the residual fistula orifice. The authors suggest that APC can be used as an alternative endoscopic technique to repair TEF when other techniques fail.

  16. Clinical analysis on argon plasma coagulation (APC) under painless colonoscopy for treatment of patients with colorectal polyp canceration.

    Science.gov (United States)

    Sun, J-Y; Sun, D-J; Li, X-J; Jiao, K; Zhai, Z-W

    2016-01-01

    To investigate the clinical effects of argon plasma coagulation combined high frequency electric knife in treating patients with colorectal polyp canceration. 56 patients diagnosed with colorectal polyp canceration were divided into control group (n=23) and observation group (n=33). Patients in the control group were treated with high frequency electric band ligation electroexcision while patients in observation group were treated with argon coagulation combined high frequency electric knife therapy. The patients were followed up for 6 months and, then, compared for their clinical effects and prognosis. The average diameter of the polyp, the ratios of sessile and flat polyps in observation group were significantly higher than those in the control group with p0.05. Further, the differences in operation completion rate and polyp resection rate at one time in observation group was significantly higher than those of control group while operative complication rate and operation time was significantly lower than those in the control group with pplasma coagulation combined high frequency electric knife could extend polyp resection indication, along with improvement in the operation effect and reduction of complications.

  17. Efficacy of argon plasma coagulation in the management of portal hypertensive gastropathy

    Science.gov (United States)

    Hanafy, Amr Shaaban; El Hawary, Amr Talaat

    2016-01-01

    Objectives: Evaluation of the outcome and experience in 2 years of management of portal hypertensive gastropathy (PHG) by argon plasma coagulation (APC) in a cohort of Egyptian cirrhotic patients. Methods: This study was conducted over a 2-year period from January 2011 to February 2013. Upper gastrointestinal endoscopy was performed to evaluate the degree and site of PHG. APC was applied to areas with mucosal vascular lesions. Results: In total, 200 cirrhotic patients were enrolled; 12 patients were excluded due to death (n = 6) caused by hepatic encephalopathy (n = 3), hepatorenal syndrome (n = 2), or chronic lymphatic leukemia (n = 1), or did not complete the treatment sessions (n = 6), so 188 patients completed the study. PHG was mainly fundic in 73 patients (38.8 %), corporeal in 66 patients (35.1 %), and pangastric in 49 patients (26.1 %) (P = 0.026). Patients were exposed to APC and received proton pump inhibitors together with propranolol at a dose sufficient to reduce the heart rate by 25 % or down to 55 beats/min. The mean (± standard deviation) number of sessions was 1.65 ± 0.8; six patients needed four sessions (3.2 %), 19 patients needed three sessions (10.1 %), 74 patients needed two sessions (39.4 %), and 89 patients needed one session (47.3 %). Patients with fundic and corporeal PHG required the lowest number of sessions (P = 0.000). Patients were followed up every 2 months for up to 1 year; the end point was a complete response with improved anemia and blood transfusion requirement which was achieved after one session in 89 patients (75.4 %), two sessions in 24 patients (20.3 %) and three sessions in five patients (4.3 %). A complete response was more prevalent in patients with corporeal and fundic PHG (P = 0.04). Conclusions: After 2 years’ experience in managing PHG, we found that a combination of APC and non-selective beta blockers was highly efficacious and safe in controlling

  18. An Inflammatory Fibroid Polyp in the Hepatic Flexure of the Colon Treated with Argon Plasma Coagulation, Endoscopic Clipping and Polypectomy

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    Ariyo Ihimoyan

    2012-01-01

    Full Text Available Inflammatory fibroid polyp (IFP is a rare benign polypoid lesion of the gastrointestinal tract. Most IFPs occur in the stomach and colonic occurrence is very rare. Histologically IFP is characterized by a mixture of numerous small vessels, fibroblasts and edematous connective tissue associated with marked inflammatory infiltration by eosinophils. We present a rare case of a pedunculated IFP in the hepatic flexure of the colon treated successfully with a combination of argon plasma coagulation, endoclipping and polypectomy. A 74-year-old asymptomatic female underwent a screening colonoscopy in our hospital. A 12-mm pedunculated polyp was found at the hepatic flexure of the colon. After saline injection, we attempted to remove the polyp with a hot snare. However the polyp stalk was extremely difficult to resect despite several attempts with the hot snare. We placed an endoclip at the base of the stalk and then applied argon plasma coagulation at 1.0 l/min and 40 W. After these measures we were able to resect the stalk and the polyp was retrieved. Histologically the polyp was located in the submucosa of the gastrointestinal tract. Proliferation of spindle cells and infiltration of inflammatory cells such as plasma cells and eosinophils were observed. The spindle cells were positive for CD34 and S100 but negative for c-kit and muscle markers. These findings are consistent with a histopathological diagnosis of IFP.

  19. From electrocautery, balloon dilatation, neodymium-doped:yttrium-aluminum-garnet (Nd:YAG) laser to argon plasma coagulation and cryotherapy

    Science.gov (United States)

    Pickering, Edward M.; Lee, Hans J.

    2015-01-01

    Over the past decade, there has been significant advancement in the development/application of therapeutics in thoracic diseases. Ablation methods using heat or cold energy in the airway is safe and effective for treating complex airway disorders including malignant and non-malignant central airway obstruction (CAO) without limiting the impact of future definitive therapy. Timely and efficient use of endobronchial ablative therapies combined with mechanical debridement or stent placement results in immediate relief of dyspnea for CAO. Therapeutic modalities reviewed in this article including electrocautery, balloon dilation (BD), neodymium-doped:yttrium-aluminum-garnet (Nd:YAG) laser, argon plasma coagulation (APC), and cryotherapy are often combined to achieve the desired results. This review aims to provide a clinically oriented review of these technologies in the modern era of interventional pulmonology (IP). PMID:26807284

  20. The role of argon plasma coagulation in the management of Barrett's esophagus: a single-center experience

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    Gad YZ

    2011-04-01

    Full Text Available Yahia Z Gad1, Adel A Zeid21Associate Professor of Internal Medicine, Mansoura Specialized Medical Hospital, Mansoura University, Mansoura, Egypt; 2Consultant Surgeon, Al Nil Hospital, Mansaura, EgyptBackground/aim: Patients with Barrett's esophagus (BE are 30 times more likely to develop esophageal adenocarcinoma (EAC than the general population. Data regarding the use of argon plasma coagulation (APC for treatment of patients with BE in Egypt are still limited. This article discusses the efficacy and safety of APC as a thermoablative modality in Egyptian patients with BE.Materials and methods: A total of 73 referred eligible patients with a confirmed endoscopic and histopathologic diagnosis of BE were enrolled in this study and subjected to thermoablation by high-power (hp-APC equipment at a 60 W setting until complete ablation or a maximum of five sessions and were followed up clinically and endoscopically at 3-month intervals. Computer-generated randomization allocated patients into APC-treated and control groups (n = 75, all of whom were treated with a proton pump inhibitor.Results: Minor and major complications occurred in 8 of 73 (10.95% and 1 of 73 (1.36% patients, respectively. Macroscopic ablation was achieved after one session in 37 of 73 (50.63% patients, and complete histologic ablation was confirmed after 167 sessions in 69 of 73 (94.52% patients. At 1-year follow-up, no relapses of BE or progression to EAC were observed.Conclusion: hp-APC at a medium-energy setting of 60 W in an acid-reduced environment can ablate BE effectively and safely with promising initial results.Keywords: Barrett's esophagus, argon plasma coagulation

  1. Argon Plasma Coagulation Therapy Versus Topical Formalin for Intractable Rectal Bleeding and Anorectal Dysfunction After Radiation Therapy for Prostate Carcinoma

    Energy Technology Data Exchange (ETDEWEB)

    Yeoh, Eric, E-mail: eric.yeoh@health.sa.gov.au [Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide (Australia); School of Medicine, University of Adelaide, Adelaide (Australia); Tam, William; Schoeman, Mark [School of Medicine, University of Adelaide, Adelaide (Australia); Department of Gastroenterology, Royal Adelaide Hospital, Adelaide (Australia); Moore, James; Thomas, Michelle [School of Medicine, University of Adelaide, Adelaide (Australia); Department of Colorectal Surgery, Royal Adelaide Hospital, Adelaide (Australia); Botten, Rochelle; Di Matteo, Addolorata [Department of Radiation Oncology, Royal Adelaide Hospital, Adelaide (Australia)

    2013-12-01

    Purpose: To evaluate and compare the effect of argon plasma coagulation (APC) and topical formalin for intractable rectal bleeding and anorectal dysfunction associated with chronic radiation proctitis. Methods and Materials: Thirty men (median age, 72 years; range, 49-87 years) with intractable rectal bleeding (defined as ≥1× per week and/or requiring blood transfusions) after radiation therapy for prostate carcinoma were randomized to treatment with APC (n=17) or topical formalin (n=13). Each patient underwent evaluations of (1) anorectal symptoms (validated questionnaires, including modified Late Effects in Normal Tissues–Subjective, Objective, Management, and Analytic and visual analogue scales for rectal bleeding); (2) anorectal motor and sensory function (manometry and graded rectal balloon distension); and (3) anal sphincteric morphology (endoanal ultrasound) before and after the treatment endpoint (defined as reduction in rectal bleeding to 1× per month or better, reduction in visual analogue scales to ≤25 mm, and no longer needing blood transfusions). Results: The treatment endpoint was achieved in 94% of the APC group and 100% of the topical formalin group after a median (range) of 2 (1-5) sessions of either treatment. After a follow-up duration of 111 (29-170) months, only 1 patient in each group needed further treatment. Reductions in rectal compliance and volumes of sensory perception occurred after APC, but no effect on anorectal symptoms other than rectal bleeding was observed. There were no differences between APC and topical formalin for anorectal symptoms and function, nor for anal sphincteric morphology. Conclusions: Argon plasma coagulation and topical formalin had comparable efficacy in the durable control of rectal bleeding associated with chronic radiation proctitis but had no beneficial effect on anorectal dysfunction.

  2. MeV Argon ion beam generation with narrow energy spread

    CERN Document Server

    Xu, Jiancai; Shen, Baifei; Zhang, Hui; Li, Shun; Yu, Yong; Li, Jinfeng; Lu, Xiaoming; Wang, Cheng; Wang, Xinliang; Liang, Xiaoyan; Leng, Yuxin; Li, Ruxin; Xu, Zhizhan

    2016-01-01

    Laser driven particle acceleration has shown remarkable progresses in generating multi-GeV electron bunches and 10s of MeV ion beams based on high-power laser facilities. Intense laser pulse offers the acceleration field of 1012 Volt per meter, several orders of magnitude larger than that in conventional accelerators, enabling compact devices. Here we report that a highly-collimated argon ion beam with narrow energy spread is produced by irradiating a 45-fs fully-relativistic laser pulse onto an argon cluster target. The highly-charged (Argon ion with charge state of 16+) heavy ion beam has a minimum absolute energy spread of 0.19 MeV per nucleon at the energy peak of 0.39 MeV per nucleon. we identify a novel scheme from particle-in-cell simulations that greatly reduces the beam energy spread. The laser-driven intense plasma wakefield has a strong modulation on the ion beam in a way that the low energy part is cut off. The pre-accelerated argon ion beam from Coulomb explosion thus becomes more mono-energetic ...

  3. Preparation of a primary argon beam for the CERN fixed target physics.

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    Küchler, D; O'Neil, M; Scrivens, R; Thomae, R

    2014-02-01

    The fixed target experiment NA61 in the North Area of the Super Proton Synchrotron is studying phase transitions in strongly interacting matter. Up to now they used the primary beams available from the CERN accelerator complex (protons and lead ions) or fragmented beams created from the primary lead ion beam. To explore a wider range of energies and densities a request was made to provide primary argon and xenon beams. This paper describes the results of the setting up and 10 week test run of the Ar(11+) beam from the 14.5 GHz ECR ion source and the linear accelerator (Linac3) at CERN.

  4. Preparation of a primary argon beam for the CERN fixed target physics

    Energy Technology Data Exchange (ETDEWEB)

    Küchler, D., E-mail: detlef.kuchler@cern.ch; O’Neil, M.; Scrivens, R. [CERN, BE Department, 1211 Geneva 23 (Switzerland); Thomae, R. [iThemba LABS, P.O. Box 722, Somerset West 7130 (South Africa)

    2014-02-15

    The fixed target experiment NA61 in the North Area of the Super Proton Synchrotron is studying phase transitions in strongly interacting matter. Up to now they used the primary beams available from the CERN accelerator complex (protons and lead ions) or fragmented beams created from the primary lead ion beam. To explore a wider range of energies and densities a request was made to provide primary argon and xenon beams. This paper describes the results of the setting up and 10 week test run of the Ar{sup 11+} beam from the 14.5 GHz ECR ion source and the linear accelerator (Linac3) at CERN.

  5. Endoscopic ablation of Barrett's esophagus using the second generation argon plasma coagulation: a prospective randomized controlled trail

    Institute of Scientific and Technical Information of China (English)

    Li Zhang; Lei Dong; Jia Liu; Xiaolan Lu; Jun Zhang

    2009-01-01

    Objective:To investigate the efficacy and safety of the second generation argon plasma coagulation(VIO APC) in the ablation of Barrett's Esophagus. Methods:A total of 35 patients with uncomplicated Barrett's esophagus entered into a prospective, randomized, unblinded study comparing the treatment VIO APC combined with a proton pump inhibiter with a proton pump inhibiter administered alone. VIO APC was performed at a power setting of 40W, and argon gas flow at 1.5-2.0 L/min, and "forced" mode. Ablative treatment was repeated until either no Barrett's epithelium remained or a maximum of 5 treatment sessions occurred. Results:In the ablation group, macroscopic complete ablation was achieved in 14 of 18 patients, and complete ablation confirmed by histology in 12 of 18 patients (P<0.01). Buried glands were observed in 2 patients who had achieved macroscopic ablation. The Barrett's mucosa averaged a reduction of 65%(range 50-75%) in the remaining 4 patients. In the control group, only 2 patients had partial regression, median 30%(range 20-40%).In the ablation group, post-treatment 4 patients had transient retrosternal pain, and 3 patients had mild epigastric discomfort. One patient had a small hemorrhage during the procedure, which ceased after norepinephrine and thrombosin were administered through the endoscope biopsy channel. No adverse events were observed in the control group. During 11.8(4-15) months follow-up, patients who had achieved the complete ablation have no evidence of relapse of Barrett's esophagus. Conclusion:VIO APC with a relatively low power setting can effectively ablate the Barrett's mucosa. No severe adverse events were observed. Long-term follow-up is needed to assess cancer prevention and the durability of the neo-squamous epithelium.

  6. Linac3 LEBT beam measurements during the 2014-2015 Argon ion run

    CERN Document Server

    Bellodi, Giulia; Maintrot, Marc; Toivanen, Ville Aleksi; CERN. Geneva. ATS Department

    2016-01-01

    Between Spring 2014 and Spring 2015, LINAC3 delivered a beam of Argon ions. A campaign of beam studies was launched with the aim of better understanding the present limitations in the machine performance in the framework of the requested intensity goals as defined by the LHC Injectors Upgrade project. Measurements were mostly focused on beam characterization in the low energy part of Linac3 (LEBT), where performance in operation is mostly limited (in terms of beam transmission). Systematic quadrupole scans provided indirect measurement of the beam transverse emittance and were used as input to improve and refine the accelerator and beam description parameters used in simulations. IBSimu studies of beam formation and extraction at the source were interfaced with particle tracking with the 3D code PATH, and the resulting predictions found good validation in the beam measurements taken during this campaign.

  7. Electron-beam-sustained discharge revisited - light emission from combined electron beam and microwave excited argon at atmospheric pressure

    CERN Document Server

    Dandl, T; Neumeier, A; Wieser, J; Ulrich, A

    2015-01-01

    A novel kind of electron beam sustained discharge is presented in which a 12keV electron beam is combined with a 2.45GHz microwave power to excite argon gas at atmospheric pressure in a continuous mode of operation. Optical emission spectroscopy is performed over a wide wavelength range from the vacuum ultraviolet (VUV) to the near infrared (NIR). Several effects which modify the emission spectra compared to sole electron beam excitation are observed and interpreted by the changing plasma parameters such as electron density, electron temperature and gas temperature.

  8. Electron-beam-sustained discharge revisited - light emission from combined electron beam and microwave excited argon at atmospheric pressure

    OpenAIRE

    Dandl, T.; Hagn, H.; Neumeier, A.; Wieser, J; Ulrich, A.

    2015-01-01

    A novel kind of electron beam sustained discharge is presented in which a 12keV electron beam is combined with a 2.45GHz microwave power to excite argon gas at atmospheric pressure in a continuous mode of operation. Optical emission spectroscopy is performed over a wide wavelength range from the vacuum ultraviolet (VUV) to the near infrared (NIR). Several effects which modify the emission spectra compared to sole electron beam excitation are observed and interpreted by the changing plasma par...

  9. Electron-beam-sustained discharge revisited — light emission from combined electron beam and microwave excited argon at atmospheric pressure

    Science.gov (United States)

    Dandl, Thomas; Hagn, Hermann; Neumeier, Alexander; Wieser, Jochen; Ulrich, Andreas

    2014-09-01

    A novel kind of electron beam sustained discharge is presented in which a 12 keV electron beam is combined with a 2.45 GHz microwave power to excite argon gas at atmospheric pressure in a continuous mode of operation. Optical emission spectroscopy is performed over a wide wavelength range from the vacuum ultraviolet (VUV) to the near infrared (NIR). Several effects which modify the emission spectra compared to sole electron beam excitation are observed and interpreted by the changing plasma parameters such as electron density, electron temperature and gas temperature.

  10. Is argon plasma coagulation an effective and safe treatment option for patients with chronic radiation proctitis after high doses of radiotherapy?

    Science.gov (United States)

    Hortelano, Eduardo; Gómez-Iturriaga, Alfonso; Ortiz-de-Zárate, Roberto; Zaballa, Manuel; Barturen, Ángel; Casquero, Francisco; San-Miguel, Íñigo; Carvajal, Carvajal; Cacicedo, Jon; Del-Hoyo, Olga; Lupiani, Javier; Pérez, Fernando; Bilbao, Pedro

    2014-03-01

    In severe cases refractory to medical treatment, APC appears to be the preferred alternative to control persistent rectal bleeding of patients with chronic radiation proctitis. Although successful outcomes have been demonstrated in patients previously treated with moderate doses of radiotherapy, there is reluctance towards its indication due to the concern of severe adverse events in patients treated with high doses of radiation. The aim of this study was to assess the efficacy and toxicity of APC in the management of bleeding radiationinduced proctitis in patients treated with high doses of radiation for prostate cancer. Data from 30 patients were treated with APC due to chronic radiation proctitis, were reviewed retrospectively. All cases had prostate cancer and 9 of them (30 %) underwent previous radical prostatectomy. The median dose of conformal 3D External Beam Radiotherapy (EBRT) delivered was 74 Gy (range 46-76). Median rectal D1cc and D2cc was 72.5 and 72.4 Gy respectively. Median rectal V70, V60 and V40 was 12, 39.5 and 80 %. Cardiovascular and digestive disease, diabetes, smoking behaviour, lowest haemoglobin and transfusion requirements were recorded. Indications for treatment with APC were anemia and persistent bleeding despite medical treatment. Argon gas flow was set at 1.8 l/min with an electrical power setting of 50 W. Median age of all patients was 69.6 years. The median lowest haemoglobin level was 9.6 g/dL. Median time between completion of radiotherapy and first session of APC was 13 months. Ninety-four therapeutic sessions were performed (median 3 sessions). Median time follow-up was 14.5 months (range 2-61). Complete response with resolved rectal bleeding was achieved in 23 patients (77 %), partial response in 5 (16 %) and no control in 2 (6 %). No patients required transfusion following therapy. Two patients developed long-term (> 6 weeks) grade 2 rectal ulceration and grade 2 rectal incontinence, respectively. The argon plasma coagulation

  11. Is argon plasma coagulation an effective and safe treatment option for patients with chronic radiation proctitis after high doses of radiotherapy?

    Directory of Open Access Journals (Sweden)

    Eduardo Hortelano

    Full Text Available Introduction: In severe cases refractory to medical treatment, APC appears to be the preferred alternative to control persistent rectal bleeding of patients with chronic radiation proctitis. Although successful outcomes have been demonstrated in patients previously treated with moderate doses of radiotherapy, there is reluctance towards its indication due to the concern of severe adverse events in patients treated with high doses of radiation. Objectives: The aim of this study was to assess the efficacy and toxicity of APC in the management of bleeding radiation-induced proctitis in patients treated with high doses of radiation for prostate cancer. Methods and materials: Data from 30 patients were treated with APC due to chronic radiation proctitis, were reviewed retrospectively. All cases had prostate cancer and 9 of them (30 % underwent previous radical prostatectomy. The median dose of conformal 3D External Beam Radiotherapy (EBRT delivered was 74 Gy (range 46-76. Median rectal D1cc and D2cc was 72.5 and 72.4 Gy respectively. Median rectal V70, V60 and V40 was 12, 39.5 and 80 %. Cardiovascular and digestive disease, diabetes, smoking behaviour, lowest haemoglobin and transfusion requirements were recorded. Indications for treatment with APC were anemia and persistent bleeding despite medical treatment. Argon gas flow was set at 1.8 l/min with an electrical power setting of 50 W. Results: Median age of all patients was 69.6 years. The median lowest haemoglobin level was 9.6 g/dL. Median time between completion of radiotherapy and first session of APC was 13 months. Ninety-four therapeutic sessions were performed (median 3 sessions. Median time follow-up was 14.5 months (range 2-61. Complete response with resolved rectal bleeding was achieved in 23 patients (77 %, partial response in 5 (16 % and no control in 2 (6 %. No patients required transfusion following therapy. Two patients developed long-term (> 6 weeks grade 2 rectal ulceration and

  12. Comparison of argon plasma coagulation in management of upper gastrointestinal angiodysplasia and gastric antral vascular ectasia hemorrhage.

    Science.gov (United States)

    Chiu, Yi-Chun; Lu, Lung-Sheng; Wu, Keng-Liang; Tam, William; Hu, Ming-Luen; Tai, Wei-Chen; Chiu, King-Wah; Chuah, Seng-Kee

    2012-06-09

    Vascular ectasias, including gastric antral vascular ectasia (GAVE) and angiodysplasia, are increasingly recognized as important sources of gastrointestinal bleeding. This study investigated and compared the efficacies and outcomes of treatment of upper gastrointestinal (UGI) angiodysplasia and GAVE hemorrhage by endoscopic argon plasma coagulation (APC). From January 2006 to December 2009, 46 patients diagnosed with upper GI bleeding caused by angiodysplasia or GAVE at a tertiary hospital were recruited into this study. They included 26 males and 20 females with an average age of 65.6 years (range, 45-90 years). All patients underwent APC for hemostasis during an endoscopic procedure. Parameters such as underlying co-morbidities, number of endoscopic treatment sessions, recurrent bleeding, and clinical outcomes during follow-up were analyzed. The 46 patients with UGI vascular ectasia hemorrhage included 27 patients with angiodysplasia and 19 with GAVE. The patients with angiodysplasia were older than those with GAVE (71.6 ± 10.2 years versus 61.8 ± 11.9 years, P = 0.005). More GAVE patients than angiodysplasia patients had co-existing liver cirrhosis (63.2% versus 25.9%, P = 0.012). The patients with GAVE had a higher rate of recurrent bleeding (78.9% versus 7.4%, P bleeding. Further multivariate analysis revealed that GAVE was the only independent risk factor for recurrent bleeding after APC treatment (OR = 0.027, P bleeding. The efficacy of APC treatment is greater for angiodysplasia than for vascular ectasia bleeding. GAVE patients have a higher recurrent bleeding rate and may require multiple treatment sessions for sustained hemostasis.

  13. Endoscopic plasma argon coagulation in treatment of weight regain after bariatric surgery: what does the patient think about this?

    Science.gov (United States)

    Marchesini, Simone Dallegrave; Baretta, Giorgio Alfredo Pedroso; Cambi, Maria Paula Carlini; Marchesini, João Batista

    2014-01-01

    Bariatric surgery, especially Roux-en-Y gastric bypass is an effective treatment for refractory morbid obesity, causing the loss of 75% of initial excess weight. After the surgery, however, weight regain can occur in 10-20% of cases. To help, endoscopic argon plasma coagulation (APC) is used to reduce the anastomotic diameter. Many patients who undergo this treatment, are not always familiar with this procedure and its respective precautions. The aim of this study was to determine how well the candidate for APC understands the procedure and absorbs the information provided by the multidisciplinary team. We prepared a questionnaire with 12 true/false questions to evaluate the knowledge of the patients about the procedure they were to undergo. The questionnaire was administered by the surgeon during consultation in the preoperative period. The patients were invited to fill out the questionnaire. We found out that the majority learned about the procedure through the internet. They knew it was an outpatient treatment, where the anesthesia was similar to that for endoscopy, and that they would have to follow a liquid diet. But none of them knew that the purpose of this diet was to improve local wound healing. Bariatric patients who have a second chance to resume weight loss, need continuous guidance. The internet should be used by the multidisciplinary team to promote awareness that APC will not be sufficient for weight loss and weight-loss maintenance in the long term. Furthermore, there is a need to clarify again the harm of drinking alcohol in the process of weight loss, making its curse widely known.

  14. Performance Of A Liquid Argon Time Projection Chamber Exposed To The WANF Neutrino Beam

    CERN Document Server

    Arneodo, F; Bonesini, M; Borio di Tigliole, A; Boschetti, B; Bueno, A; Calligarich, E; Casagrande, F; Cavalli, D; Cavanna, F; Cennini, P; Centro, Sandro; Cesana, E; Cline, D; Curioni, A; De Mitri, I; De Vecchi, C; Dolfini, R; Ferrari, A; Ghezzi, A; Guglielmi, A; Kisiel, J; Mannocchi, G; Martinez de la Ossa, A; Matthey, C; Mauri, F; Montanari, C; Navas, S; Negri, P; Nicoletto, Marino; Otwinowski, S; Paganoni, M; Palamara, O; Pepato, Adriano; Periale, L; Piano Mortari, G; Picchi, P; Pietropaolo, F; Puccini, A; Pullia, A; Ragazzi, S; Rancati, T; Rappoldi, A; Raselli, G L; Redaelli, N; Rondio, E; Rubbia, André; Rubbia, Carlo; Sala, P R; Sergiampietri, F; Sobczyk, J; Suzuki, S; Tabarelli de Fatis, T; Terrani, M; Terranova, F; Tonazzo, A; Ventura, Sandro; Vignoli, C; Wang, H; Zalewska A

    2006-01-01

    We present the results of the first exposure of a Liquid Argon TPC to a multi-GeV neutrino beam. The data have been collected with a 50 liters ICARUS-like chamber located between the CHORUS and NOMAD experiments at the CERN West Area Neutrino Facility (WANF). We discuss both the instrumental performance of the detector and its capability to identify and reconstruct low multiplicity neutrino interactions.

  15. Two-dimensional numerical simulation of a continuous needle-like argon electron-beam plasma

    Science.gov (United States)

    Bai, Xiaoyan; Chen, Chen; Li, Hong; Liu, Wandong

    2017-05-01

    The fluid-Poisson equations coupled with the Monte Carlo method were used to simulate the spatio-temporal behavior of a needle-like argon electron-beam plasma. Based on the Monte Carlo simulation, three coupled parameters characterizing the electron beam propagation for initial energies above several keV were expressed using a universal dimensionless shape function given in terms of the beam range multiplied by a normalized coefficient. Therefore, a single run of the Monte Carlo code was sufficient for the simulations over a wide range of conditions. The spatial potential as a function of space and time was studied from the fluid-Poisson equations. The results indicate that the time evolution of the spatial potential was influenced by the presence of the slowed-down electrons and the flying beam electrons, whereas the potential in quasi-equilibrium was mainly determined from the spatial distribution of the secondary electron. The potential in quasi-equilibrium was positive near the beam entrance and most negative along the tip of the beam range, which was a result of ambipolar diffusion. When the enclosing boundary surfaces were moved within the beam range, the potential was nearly positive everywhere. The calculation on the diffusion-drift flux indicated that the net current of the secondary electrons flowing back to the incident plane in quasi-equilibrium balanced the incident beam current, which was the so-called return current in the three-dimensional space.

  16. CAPTAIN-Minerνa. Neutrino-Argon Scattering in a Medium-Energy Neutrino Beam

    Energy Technology Data Exchange (ETDEWEB)

    Mauger, Christopher M. [Los Alamos National Lab. (LANL), Los Alamos, NM (United States)

    2015-10-29

    The NuMI facility at Fermilab is currently providing an extremely intense beam of neutrinos for the NOνA, MINERνA and MINOS+ experiments. By installing the 5-ton CAPTAIN liquid argon TPC in front of the MINERνA detector in the NuMI beamline and combining the data from the CAPTAIN, MINERνA and MINOS+ detectors, a broad program of few-GeV neutrino cross section measurements on argon can be pursued. These measurements will be extremely helpful for future oscillation experiments. By directly comparing the cross sections on argon to MINERνA’s scintillator (CH) target, a new level of precision can be achieved in the measurements of the effects of the nucleus on neutrino interactions. These effects are of interest to not only the particle physics but also the nuclear physics community. This document describes in detail the physics goals of the CAPTAIN-MINERνA experiment, in addition to a first estimate of the technical resources required to install, commission and operate the CAPTAIN detector in front of the MINERVA detector.

  17. Two Dimensional LIF Measurements and Potential Structure of Ion Beam Formation in an Argon Helicon Plasma

    Science.gov (United States)

    Aguirre, Evan; Scime, Earl; Good, Timothy

    2016-10-01

    We report 2-dimensional, spatially resolved observations of ion beam formation in an expanding helicon plasma. Previous studies found that a current free double layer (CFDL) spontaneously arises at low pressure, below 1 mT. We use Laser Induced Fluorescence (LIF), a non-perturbative diagnostic to measure the ion velocity distribution functions (IVDFs) of argon ions both parallel and perpendicular to the background magnetic field. We report ion beam formation as a function of the expansion chamber magnetic field (0-108 G). The ion beam appears peaked in the center of the expansion chamber and decays over a few centimeters radially. We also report the potential structure of the plasma obtained with a planar Langmuir probe. To obtain meaningful Langmuir probe measurements, averages of tens of current-voltage are needed to reduce the effects of large electrostatic fluctuations that arise in plasmas that generate ion beams. We report the dependence of density, electron temperature, and floating potential on radial and axial position in the expansion plume. NSF Award PHYS-1360278.

  18. Effect of ribs in HIFU beam path on formation of coagulative necrosis in goat liver

    Science.gov (United States)

    Li, Faqi; Gong, Xiaobo; Hu, Kai; Li, Chongyan; Wang, Zhibiao

    2006-05-01

    The motives of the work are to explore the effect of ribs in HIFU beam path on HIFU ablation goat liver. A model-JC Focused Ultrasound Tumor Therapeutic System was used. A 0.75 MHz focused transducer with 150mm aperture and 120mm focal length was used in all experiment. Acoustical power can be adjusted. 30 goats were divided into control group (HIFU beam through rib cage, HIFU alone), experiment group 1(HIFU beam through rib cage, HIFU combined with microbubble) and experiment group 2(Ribs in HIFU beam path were surgically removed, HIFU alone). 20 targeted regions at 5cm away from skin surface were applied for creating necrosis with linear scanning of 15mm length using HIFU in 3 groups. All animals were sacrificed two days later and exposed organs were dissected. After obtaining the maximal section, the volumes of the necrotic regions were measured, then to calculate Energy Efficiency Factor (EEF). Researched results showed that Ribs in HIFU beam path affected the formation of coagulative necrosis and enhanced EEF in control group. HIFU combined with microbubble could enhance the formation of coagulative necrosis and decrease EEF.

  19. Scanning-probe-microscopy of polyethylene terephthalate surface treatment by argon ion beam

    Energy Technology Data Exchange (ETDEWEB)

    Espinoza-Beltran, Francisco [Polymer & Biopolymer Group, Libramiento Norponiente no. 2000, Cinvestav Queretaro, Queretaro 76230 (Mexico); Sanchez, Isaac C. [Department of Chemical Engineering, The University of Texas at Austin, Austin, TX 78712 (United States); España-Sánchez, Beatriz L.; Mota-Morales, Josué D.; Carrillo, Salvador; Enríquez-Flores, C.I. [Polymer & Biopolymer Group, Libramiento Norponiente no. 2000, Cinvestav Queretaro, Queretaro 76230 (Mexico); Poncin-Epaillard, Fabienne, E-mail: epaill@univ-lemans.fr [Institute for Molecules and Materials, UMR CNRS 6283, Av. O. Messiaen, Universitè du Maine, Le Mans 72085 (France); Luna-Barcenas, Gabriel, E-mail: gluna@qro.cinvestav.mx [Polymer & Biopolymer Group, Libramiento Norponiente no. 2000, Cinvestav Queretaro, Queretaro 76230 (Mexico)

    2015-11-01

    Highlights: • Kelvin-probe-force microscopy helps study of PET surface treated by Ar ion beam. • Ar ion beam surface treatment promotes chain scission and N insertion. • Surface roughness and work function increases as intensity of ion energy increases. • Adhesive force of PET decrease due to the surface changes by ion bombardment. - Abstract: The effect of argon (Ar{sup +}) ion beam treatment on the surface of polyethylene terephthalate (PET) samples was studied by scanning probe microscopy (SPM) and the changes in surface topography were assessed by atomic force microscopy (AFM). Kelvin probe force microscopy (KPFM) sheds light of adhesion force between treated polymer films and a Pt/Cr probe under dry conditions, obtaining the contact potential difference of material. As a result of Ar{sup +} ion bombardment, important surface chemical changes were detected by X-ray photoelectron spectroscopy (XPS) measurements such as chains scission and incorporation of nitrogen species. Ion beam treatment increases the surface roughness from 0.49 ± 0.1 nm to 7.2 ± 0.1 nm and modify the surface potential of PET samples, decreasing the adhesive forces from 12.041 ± 2.1 nN to 5.782 ± 0.06 nN, and producing a slight increase in the electronic work function (Φ{sub e}) from 5.1 V (untreated) to 5.2 V (treated). Ar{sup +} ion beam treatment allows to potentially changing the surface properties of PET, modifying surface adhesion, improving surface chemical changes, wetting properties and surface potential of polymers.

  20. Safety and efficacy of argon plasma coagulator ablation therapy for flat colorectal adenomas Seguridad y eficacia de la ablación de pólipos colorrectales con argón plasma

    OpenAIRE

    García, A.; O. Núñez; C. González-Asanza; Parera, A; L. Menchén; Ripoll, C.; Senent, C; E. Cos; P. Menchén

    2004-01-01

    Introduction: argon-plasma coagulation (APC) has been used safely and efficaciously in multiple settings including colon polyp treatment. The aim of this study was to evaluate APC efficacy and safety in the treatment of flat colorectal adenomas. Materials and methods: APC ablation was prospectively performed and evaluated in 22 consecutive patients with colorectal adenomas, 11 of which had large sessile adenomas that were treated with piecemeal polypectomy and APC ablation of residual adenoma...

  1. Comparison of Hemostatic Efficacy of Argon Plasma Coagulation with and without Distilled Water Injection in Treating High-Risk Bleeding Ulcers

    Directory of Open Access Journals (Sweden)

    Yuan-Rung Li

    2014-01-01

    Full Text Available Background. Argon plasma coagulation (APC is useful to treat upper gastrointestinal bleeding, but its hemostatic efficacy has received little attention. Aims. This investigation attempted to determine whether additional endoscopic injection before APC could improve hemostatic efficacy in treating high-risk bleeding ulcers. Methods. From January 2007 to April 2011, adult patients with high-risk bleeding ulcers were included. This investigation compared APC plus distilled water injection (combined group to APC alone for treating high-risk bleeding ulcers. Outcomes were assessed based on initial hemostasis, surgery, blood transfusion, hospital stay, rebleeding, and mortality at 30 days posttreatment. Results. Totally 120 selected patients were analyzed. Initial hemostasis was accomplished in 59 patients treated with combined therapy and 57 patients treated with APC alone. No significant differences were noted between these groups in recurred bleeding, emergency surgery, 30-day mortality, hospital stay, or transfusion requirements. Comparing the combined end point of mortality plus the failure of initial hemostasis, rebleeding, and the need for surgery revealed an advantage for the combined group (P=0.040. Conclusions. Endoscopic therapy with APC plus distilled water injection was no more effective than APC alone in treating high-risk bleeding ulcers, whereas combined therapy was potentially superior for patients with poor overall outcomes.

  2. Fragmentation of bile duct stones: a prospective systematic in vitro evaluation of argon plasma coagulation, cryotechnology, and water-jet technology.

    Science.gov (United States)

    Eickhoff, A; Koberstein, S; Rothsching, M; Gemmel, C; Eickhoff, J C; Riemann, J F; Enderle, M D

    2009-08-01

    Choledocholithiasis is a common disease in the West. Lithotripsy by mechanical methods using baskets and by laser or electrohydraulic methods varies in effectiveness. With argon plasma coagulation (APC), high temperatures are used for devitalization and fragmentation; cryogenic techniques use the selective controlled application of freeze-thaw cycles to devitalize pathological tissue; and the dissecting water jet exploits the high pressure action of a thin laminar jet. We aimed to assess the feasibility and effectiveness of APC, cryotechnology, and the dissecting water jet as options for the fragmentation of bile duct stones. In an in vitro feasibility study, we evaluated the fragmentation of 120 bile duct stones treated with the three methods. Primary measures were assessment of the fragmentation rate, fragmentation effect, and energy application for each technology. Fragmentation was seen in only 10 % of stones treated cryogenically using liquid nitrogen. APC at a power setting of 30 - 50 W fragmented all the cholesterol stones, but results with hard pigment stones were unsatisfactory even at high energies of a 100 W setting and long application time. Using the water jet, all 40 stones (100 %) were cracked effectively and completely with a pressure of 10 - 50 bar. In this feasibility study, the first of its kind, only the water-jet device demonstrated efficient fragmentation of large bile duct stones in vitro. APC and cryotechnology are not suitable for the treatment of bile duct stones; the fragmentation rate with these methods was inadequate.

  3. 内镜下HFEC术对比APC术治疗大肠息肉的疗效探究%Clinical efficacy of endoscopic high frequency electric coagulation and argon plasma coagulation for colorectal polyps

    Institute of Scientific and Technical Information of China (English)

    刘伟

    2015-01-01

    目的 探究内镜下高频电凝切除术(High frequency electric coagulation,HFEC)与氩离子凝固术(Argon plasma coagulation,APC)在大肠息肉(Colorectal polyps,CP)治疗中的价值,为临床上CP治疗方式的选择提供依据.方法选择2009年3月-2014年3月在杭州师范大学附属医院接受治疗的CP患者980例,随机分成HFEC组490例(息肉653枚)和APC组490例(息肉688枚),HFEC组患者采用HFEC切除治疗,APC组则采用APC术治疗.治疗后,统计2组患者一次清除率和并发症发生率,据此评价两种术式对CP治疗的价值.结果采用SPSS19.0进行统计学分析,行x2检验,以P<0.05为差异具有统计学意义.结果 APC组一次切除息肉635枚,两次及以上切除53枚,一次切除率为92.3%,而HFEC组一次切除息肉562枚,两次及以上切除91枚,一次切除率为86.1%,2组一次切除率比较,差异具有统计学意义(x2 =13.58,P<0.05);APC组发生腹胀22例,腹痛13例,穿孔1例,出血2例,并发症率为7.8%;HFEC组发生腹胀34例,腹痛21例,穿孔6例,出血9例,并发症率为14.3%,2组并发症率比较,差异具有统计学意义(x2=10.66,P<0.05).结论 APC术治疗CP一次切除率高,且并发症低,安全可靠,是CP患者较佳的治疗方式.

  4. Enhancing ion yields in time-of-flight-secondary ion mass spectrometry: a comparative study of argon and water cluster primary beams.

    Science.gov (United States)

    Sheraz née Rabbani, Sadia; Razo, Irma Berrueta; Kohn, Taylor; Lockyer, Nicholas P; Vickerman, John C

    2015-02-17

    Following from our previous Letter on this topic, this Article reports a detailed study of time-of-flight-secondary ion mass spectrometry (TOF-SIMS) positive ion spectra generated from a set of model biocompounds (arginine, trehalose, DPPC, and angiotensin II) by water cluster primary ion beams in comparison to argon cluster beams over a range of cluster sizes and energies. Sputter yield studies using argon and water beams on arginine and Irganox 1010 have confirmed that the sputter yields using water cluster beams lie on the same universal sputtering curve derived by Seah for argon cluster beams. Thus, increased ion yield using water cluster beams must arise from increased ionization. The spectra and positive ion signals observed using cluster beams in the size range from 1,000 to 10,000 and the energy range 5-20 keV are reported. It is confirmed that water cluster beams enhance proton related ionization over against argon beams to a significant degree such that enhanced detection sensitivities from 1 μm(2) in the region of 100 to 1,000 times relative to static SIMS analysis with Ar2000 cluster beams appear to be accessible. These new studies show that there is an unexpected complexity in the ionization enhancement phenomenon. Whereas optimum ion yields under argon cluster bombardment occur in the region of E/n ≥ 10 eV (where E is the beam energy and n the number of argon atoms in the cluster) and fall rapidly when E/n < 10 eV; for water cluster beams, ion yields increase significantly in this E/n regime (where n is the number of water molecules in the cluster) and peak for 20 keV beams at a cluster size of 7,000 or E/n ∼3 eV. This important result is explored further using D2O cluster beams that confirm that in this low E/n regime protonation does originate to a large extent from the water molecules. The results, encouraging in themselves, suggest that for both argon and water cluster beams, higher energy beams, e.g., 40 and 80 keV, would enable larger

  5. Crossed-beam time-of-flight study of metastable helium in collisions with helium, neon, and argon

    Energy Technology Data Exchange (ETDEWEB)

    Fiering, K.B.

    1981-01-01

    Absolute total integral velocity-resolved cross sections have been measured for collisions of helium singlet (2/sup 1/S/sub 0/) and triplet (2/sup 3/S/sub 1/) metastables with ground-state helium, neon, and argon in the thermal velocity range of 1.0 to 3.5 x 10/sup 5/ cm/sec. Additional measurements on the He/sup +/-Ne system with a large input acceptance angle at the detector failed to show previously predicted sharply-rising velocity structure in the inelastic transfer cross sections. The measurements were taken with a crossed-beam time-of-flight apparatus.

  6. a Crossed-Beam Time-Of Study of Metastable Helium in Collisions with Helium, Neon, and Argon.

    Science.gov (United States)

    Fiering, Kenneth Barratt

    Absolute total integral velocity-resolved cross sections have been measured for collisions of helium singlet (2('1)S(,0)) and triplet (2('3)S(,1)) metastables with ground-state helium, neon, and argon in the thermal velocity range of 1.0-3.5 x 10('5) cm/sec. Additional measurements on the He*-Ne system with a large input acceptance angle at the detector failed to show previously predicted sharply -rising velocity structure in the inelastic transfer cross sections. The measurements were taken with a crossed-beam time-of-flight apparatus.

  7. Compact cryogenic source of periodic hydrogen and argon droplet beams for relativistic laser-plasma generation

    Energy Technology Data Exchange (ETDEWEB)

    Fraga, R. A. Costa; Kalinin, A.; Kuehnel, M.; Schottelius, A. [Institut fuer Kernphysik, J. W. Goethe-Universitaet, Max-von-Laue-Str. 1, 60438 Frankfurt am Main (Germany); Hochhaus, D. C.; Neumayer, P. [EMMI Extreme Matter Institute and Research Division, GSI Helmholtzzentrum fuer Schwerionenforschung, Planckstr. 1, 64291 Darmstadt (Germany); FIAS Frankfurt Institute for Advanced Studies, J. W. Goethe-Universitaet, Ruth-Moufang-Str. 1, 60438 Frankfurt am Main (Germany); Polz, J. [Institut fuer Optik und Quantenelektronik, Max-Wien-Platz 1, 07743 Jena (Germany); Kaluza, M. C. [Institut fuer Optik und Quantenelektronik, Max-Wien-Platz 1, 07743 Jena (Germany); Helmholtz-Institut Jena, Froebelstieg 3, 07743 Jena (Germany); Grisenti, R. E. [Institut fuer Kernphysik, J. W. Goethe-Universitaet, Max-von-Laue-Str. 1, 60438 Frankfurt am Main (Germany); GSI Helmholtzzentrum fuer Schwerionenforschung, Planckstr. 1, 64291 Darmstadt (Germany)

    2012-02-15

    We present a cryogenic source of periodic streams of micrometer-sized hydrogen and argon droplets as ideal mass-limited target systems for fundamental intense laser-driven plasma applications. The highly compact design combined with a high temporal and spatial droplet stability makes our injector ideally suited for experiments using state-of-the-art high-power lasers in which a precise synchronization between the laser pulses and the droplets is mandatory. We show this by irradiating argon droplets with multi-terawatt pulses.

  8. Investigations on the time evolution of the plasma density in argon electron-beam plasma at intermediate pressure

    Science.gov (United States)

    Xiaoyan, BAI; Chen, CHEN; Hong, LI; Wandong, LIU

    2017-03-01

    The time evolution of the argon electron-beam plasma at intermediate pressure and low electron beam intensity was presented. By applying the amplitude modulation with the frequency of 20 Hz on the stable beam current, the plasma evolution was studied. A Faraday cup was used for the measurement of the electron beam current and a single electrostatic probe was used for the measurement of the ion current. Experimental results indicated that the ion current was in phase with the electron beam current in the pressure range from 200 Pa to 3000 Pa and in the beam current range lower than 20 mA, the residual density increased approximately linearly with the maximum density in the log-log plot and the fitting coefficient was irrelative to the pressure. And then three kinds of kinetic models were developed and the simulated results given by the kinetic model, without the consideration of the excited atoms, mostly approached to the experimental results. This indicated that the effect of the excited atoms on the plasma density can be ignored at intermediate pressure and low electron beam current intensity, which can greatly simplify the kinetic model. In the end, the decrease of the plasma density when the beam current was suddenly off was studied based on the simplified model and it was found that the decease characteristic at intermediate pressure was approximate to the one at high pressure at low electron beam intensity, which was in good accordance with the experimental results. Supported by National Natural Science Foundations of China (No. 11375187) and the Foundation of State key Laboratory of China (No. SKLIPR1510).

  9. Test beam results of a stereo preshower integrated in the liquid argon accordion calorimeter

    CERN Document Server

    Davis, R; Greenious, G; Kitching, P; Olsen, B; Pinfold, James L; Rodning, N L; Boos, E; Zhautykov, B O; Aubert, Bernard; Bazan, A; Beaugiraud, B; Boniface, J; Colas, Jacques; Eynard, G; Jézéquel, S; Le Flour, T; Linossier, O; Nicoleau, S; Sauvage, G; Thion, J; Van den Plas, D; Wingerter-Seez, I; Zitoun, R; Zolnierowski, Y; Chmeissani, M; Fernández, E; Garrido, L; Martínez, M; Padilla, C; Citterio, M; Gordon, H A; Lissauer, D; Ma, H; Makowiecki, D S; Radeka, V; Rahm, David Charles; Rescia, S; Stephani, D; Takai, H; Baisin, L; Berset, J C; Chevalley, J L; Gianotti, F; Gildemeister, O; Marin, C P; Nessi, Marzio; Poggioli, Luc; Richter, W; Vuillemin, V; Baze, J M; Delagnes, E; Gosset, L G; Lavocat, P; Lottin, J P; Mansoulié, B; Meyer, J P; Renardy, J F; Schwindling, J; Simion, S; Taguet, J P; Teiger, J; Walter, C; Collot, J; de Saintignon, P; Hostachy, J Y; Mahout, G; Barreiro, F; Del Peso, J; García, J; Hervás, L; Labarga, L; Romero, P; Scheel, C V; Chekhtman, A; Cousinou, M C; Dargent, P; Dinkespiler, B; Etienne, F; Fassnacht, P; Fouchez, D; Martin, L; Miotto, A; Monnier, E; Nagy, E; Olivetto, C; Tisserant, S; Battistoni, G; Camin, D V; Cavalli, D; Costa, G; Cozzi, L; Fedyakin, N N; Ferrari, A; Mandelli, L; Mazzanti, M; Perini, L; Resconi, S; Sala, P R; Beaudoin, G; Depommier, P; León-Florián, E; Leroy, C; Roy, P; Augé, E; Breton, D; Chase, Robert L; Chollet, J C; de La Taille, C; Fayard, Louis; Fournier, D; González, J; Hrisoho, A T; Jacquier, Y; Merkel, B; Nikolic, I A; Noppe, J M; Parrour, G; Pétroff, P; Puzo, P; Richer, J P; Schaffer, A C; Seguin-Moreau, N; Serin, L; Tisserand, V; Veillet, J J; Vichou, I; Canton, B; David, J; Genat, J F; Imbault, D; Le Dortz, O; Savoy-Navarro, Aurore; Schwemling, P; Eek, L O; Lund-Jensen, B; Söderqvist, J; Astbury, Alan; Keeler, Richard K; Lefebvre, M; Robertson, S; White, J

    1998-01-01

    This paper describes the construction of an integrated preshower within the RD3 liquid argon accordion calorimeter. It has a stereo view which enables the measurement of two transverse coordinates. The prototype was tested at CERN with electrons, photons and muons to validate its capability to work at LHC ( Energy resolution, impact point resolution, angular resolution, $\\pi^o$/$\\gamma$ rejection ).

  10. Argon cluster ion beams for organic depth profiling: results from a VAMAS interlaboratory study.

    Science.gov (United States)

    Shard, Alexander G; Havelund, Rasmus; Seah, Martin P; Spencer, Steve J; Gilmore, Ian S; Winograd, Nicholas; Mao, Dan; Miyayama, Takuya; Niehuis, Ewald; Rading, Derk; Moellers, Rudolf

    2012-09-18

    The depth profiling of organic materials with argon cluster ion sputtering has recently become widely available with several manufacturers of surface analytical instrumentation producing sources suitable for surface analysis. In this work, we assess the performance of argon cluster sources in an interlaboratory study under the auspices of VAMAS (Versailles Project on Advanced Materials and Standards). The results are compared to a previous study that focused on C(60)(q+) cluster sources using similar reference materials. Four laboratories participated using time-of-flight secondary-ion mass spectrometry for analysis, three of them using argon cluster sputtering sources and one using a C(60)(+) cluster source. The samples used for the study were organic multilayer reference materials consisting of a ∼400-nm-thick Irganox 1010 matrix with ∼1 nm marker layers of Irganox 3114 at depths of ∼50, 100, 200, and 300 nm. In accordance with a previous report, argon cluster sputtering is shown to provide effectively constant sputtering yields through these reference materials. The work additionally demonstrates that molecular secondary ions may be used to monitor the depth profile and depth resolutions approaching a full width at half maximum (fwhm) of 5 nm can be achieved. The participants employed energies of 2.5 and 5 keV for the argon clusters, and both the sputtering yields and depth resolutions are similar to those extrapolated from C(60)(+) cluster sputtering data. In contrast to C(60)(+) cluster sputtering, however, a negligible variation in sputtering yield with depth was observed and the repeatability of the sputtering yields obtained by two participants was better than 1%. We observe that, with argon cluster sputtering, the position of the marker layers may change by up to 3 nm, depending on which secondary ion is used to monitor the material in these layers, which is an effect not previously visible with C(60)(+) cluster sputtering. We also note that electron

  11. Compact Cryogenic Source of Periodic Hydrogen and Argon Droplet Beams for Intense Laser-Plasma Generation

    CERN Document Server

    Fraga, R A Costa; Kühnel, M; Hochhaus, D C; Schottelius, A; Polz, J; Kaluza, M C; Neumayer, P; Grisenti, R E

    2011-01-01

    We present a cryogenic source of periodic streams of micrometer-sized hydrogen (H2) and argon (Ar) droplets as ideal mass-limited target systems for fundamental intense laser-driven plasma applications. The highly compact design combined with a high temporal and spatial droplet stability makes our injector ideally suited for experiments using state-of-the-art low-repetition rate high-power lasers, in which a precise synchronization between the laser pulses and the droplets is mandatory. We demonstrate this explicitly by irradiating Ar droplets with pulses from a Petawatt laser.

  12. Characterization of CdZnTe after argon ion beam bombardment

    Energy Technology Data Exchange (ETDEWEB)

    Bensalah, H., E-mail: hakima.bensalah@uam.es [Departamento de Fisica de Materiales, Laboratorio de Crecimiento de Cristales, Facultad de Ciencias, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid (Spain); Hortelano, V. [GdS-Optronlab Group, Departamento Fisica Materia Condensada, Universidad de Valladolid, Edificio I-D, Paseo de Belen 1, 47011 Valladolid (Spain); Plaza, J.L. [Departamento de Fisica de Materiales, Laboratorio de Crecimiento de Cristales, Facultad de Ciencias, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid (Spain); Martinez, O. [GdS-Optronlab Group, Departamento Fisica Materia Condensada, Universidad de Valladolid, Edificio I-D, Paseo de Belen 1, 47011 Valladolid (Spain); Crocco, J.; Zheng, Q.; Carcelen, V.; Dieguez, E. [Departamento de Fisica de Materiales, Laboratorio de Crecimiento de Cristales, Facultad de Ciencias, Universidad Autonoma de Madrid, Cantoblanco, 28049 Madrid (Spain)

    2012-12-05

    Highlights: Black-Right-Pointing-Pointer After argon irradiation using low fluence, the defects on surface were removed. Black-Right-Pointing-Pointer The PL intensity increases after irradiation. This increase should be related to the improved quality of the CdZnTe surfaces. Black-Right-Pointing-Pointer Irradiation process lead to an elimination of Te precipitates from the surfaces of the CdZnTe samples. - Abstract: The objective of this work is to analyze the effects of argon ion irradiation process on the structure and distribution of Te inclusions in Cd{sub 1-x}Zn{sub x}Te crystals. The samples were treated with different ion fluences ranging from 2 to 8 Multiplication-Sign 10{sup 17} cm{sup -2}. The state of the samples before and after irradiation were studied by Scanning Electron Microscopy (SEM), Atomic Force Microscopy (AFM), Cathodoluminescence, Photoluminescence, and micro-Raman spectroscopy. The effect of the irradiation on the surface of the samples was clearly observed by SEM or AFM. Even for small fluences a removal of polishing scratches on the sample surfaces was observed. Likely correlated to this effect, an important enhancement in the luminescence intensity of the irradiated samples was observed. An aggregation effect of the Te inclusions seems to occur due to the Ar bombardment, which are also eliminated from the surfaces for the highest ion fluences used.

  13. Performance of the ATLAS liquid argon forward calorimeter in beam tests

    CERN Document Server

    Archambault, J P; Cadabeschi, M; Epshteyn, V; Galt, C; Gillberg, D; Gorbounov, P; Heelan, L; Khakzad, M; Khovanskiy, V; Krieger, P; Loch, P; McCarthy, T G; Oakham, F G; Orr, R S; Rutherfoord, J; Savine, A; Schram, M; Shatalov, P; Shaver, L; Shupe, M; Strickland, V; Thompson, P; Tsukerman, I

    2013-01-01

    One of two ATLAS Forward Calorimeters, consisting of threemodules, one behind the other, was exposed to particle beams ofknown energies in order to study the detector performance with andwithout the presence of upstream material in the beam, and at theinner edge of the acceptance where shower energy containment isincomplete. Data were taken in the H6 beamline at CERN usingelectron and hadron beams with energies from 10 to 200 GeV.Results related to the intrinsic detector calibration, based on datataken with a minimal amount of material in front of the detector,have been previously published, but are updated here. This paperfocuses on studies of data taken with additional upstream materialin place. The effects of this additional material on the linearityand resolution of the response are presented. The response at theinner edge of the acceptance is also investigated. For all analyses,results based on a GEANT4 simulation of the beam-test setup anddetector response are also presented.

  14. Watermelon stomach: clinical aspects and treatment with argon plasma coagulation Ectasia vascular do antro gástrico ("watermelon stomach": aspectos clínicos e tratamento com coagulação com plasma de argônio

    Directory of Open Access Journals (Sweden)

    Dalton M. Chaves

    2006-09-01

    Full Text Available BACKGROUND: Gastric antral vascular ectasia is a disorder whose pathogenetic mechanism is unknown. The endoscopic treatment with argon plasma coagulation has been considered one of the best endoscopic therapeutic options. AIM: To analyze the endoscopic and clinical features of gastric antral vascular ectasia and its response to the argon plasma coagulation treatment. PATIENTS AND METHODS: Eighteen patients were studied and classified into two groups: group 1 - whose endoscopic aspect was striped (watermelon or of the diffuse confluent type; group 2 - diffuse spotty nonconfluent endoscopic aspect. RESULTS: Group 1 with eight patients, all having autoimmune antibodies, but one, whose antibodies were not searched for. Three were cirrhotic and three had hypothyroidism. All had gastric mucosa atrophy. In group 2, with 10 patients, all had non-immune liver disease, with platelet levels below 90.000. Ten patients were submitted to argon plasma coagulation treatment, with 2 to 36 months of follow-up. Lesions recurred in all patients who remained in the follow-up program and one did not respond to treatment for acute bleeding control. CONCLUSION: There seem to be two distinct groups of patients with gastric antral vascular ectasia: one related to immunologic disorders and other to non-immune chronic liver disease and low platelets. The endoscopic treatment using argon plasma coagulation had a high recurrence in the long-term evaluation.RACIONAL: "Watermelon stomach" ou ectasia vascular do antro gástrico é uma doença de etiopatogenia desconhecida. O tratamento endoscópico através da coagulação com plasma de argônio é considerado uma das melhores opções terapêuticas. OBJETIVO: Analisar os aspectos clínicos e endoscópicos da ectasia vascular do antro gástrico e a resposta ao tratamento com coagulação com plasma de argônio. PACIENTES E MÉTODOS: Dezoito pacientes foram estudados e classificados em dois grupos: grupo I - oito pacientes que

  15. Anomalous argon excitation in pulse supersonic flows of Ar + CH sub 4 , Ar + SiH sub 4 and Ar + CH sub 4 + SiH sub 4 mixtures, activated with an electron beam

    CERN Document Server

    Madirbaev, V Z; Korobejshchikov, N G; Sharafutdinov, R G

    2001-01-01

    The processes of energy exchange in the supersonic flows of the argon mixtures with methane and silane, activated by the electron beam, are studied. It is shown, that at the initial stage of condensation in the flux there takes place selective excitation of the argon atoms energy levels. The boundary parameters, whereby the effect of the anomalous radiation excitation is observed, are determined

  16. Effectiveness of argon plasma coagulation in the treatment of chronic actinic proctitis Efectividad de la fulguración con argón plasma en el tratamiento de la proctitis actínica crónica

    Directory of Open Access Journals (Sweden)

    V. Tormo

    2009-02-01

    Full Text Available Introduction: there are two kinds of actinic proctitis - one is acute and self-limited, and lasts about 3 months; the other is chronic and develops months to years after radiation therapy. The incidence of chronic actinic proctitis is about 5-20% of radiated prostate tumors. Objective: to evaluate the effectiveness of argon plasma coagulation in the treatment of chronic actinic proctitis. Material and method: a retrospective search of patients with the diagnosis of actinic proctitis. The number of argon plasma coagulation therapies needed to achieve the symptom resolution was analyzed. Results: we found 22 patients with a diagnosis of actinic proctitis. Nineteen were males (86.7% and three (13.6% were females. Nineteen patients (86.4% had a diagnosis of prostate adenocarcinoma, one had a diagnosis of squamous-cell cervix carcinoma (4.5%, and two had a diagnosis of endometrial carcinoma (9.1%. The mean number of coagulation sessions needed for symptom resolution was 2.58 (absolute range 1-7 with a median of 2 sessions. Conclusion: multiple treatments are described in the literature. None of them have shown promising results. Our results suggest that argon plasma coagulation is effective in the treatment of this condition, and achieves a rapid and sustained response with few sessions and a good safety profile.Introducción: existen 2 tipos de proctitis actínica, una aguda autolimitada, que dura aproximadamente 3 meses y otra crónica que aparece a los meses o años de la radioterapia. La incidencia de proctitis actínica crónica es del 5-20% de los tumores prostáticos irradiados. Objetivo: evaluar la efectividad de la fulguración con argón plasma en el tratamiento de este tipo de proctitis. Material y método: estudio retrospectivo. Realizamos una búsqueda retrospectiva de aquellos pacientes diagnosticados de proctitis actínica entre 2004 y 2007. Analizamos el número de sesiones de fulguración con plasma de argón que fueron necesarias

  17. Transparent and electrically conductive GaSb/Si direct wafer bonding at low temperatures by argon-beam surface activation

    Science.gov (United States)

    Predan, F.; Reinwand, D.; Klinger, V.; Dimroth, F.

    2015-10-01

    Direct wafer bonds of the material system n-GaSb/n-Si have been achieved by means of a low-temperature direct wafer bonding process, enabling an optical transparency of the bonds along with a high electrical conductivity of the boundary layer. In the used technique, the surfaces are activated by sputter-etching with an argon fast-atom-beam (FAB) and bonded in ultra-high vacuum. The bonds were annealed at temperatures between 300 and 400 °C, followed by an optical, mechanical and electrical characterization of the interface. Additionally, the influence of the sputtering on the surface topography of the GaSb was explicitly investigated. Fully bonded wafer pairs with high bonding strengths were found, as no blade could be inserted into the bonds without destroying the samples. The interfacial resistivities of the bonded wafers were significantly reduced by optimizing the process parameters, by which Ohmic interfacial resistivities of less than 5 mΩ cm2 were reached reproducibly. These promising results make the monolithic integration of GaSb on Si attractive for various applications.

  18. Production of highly charged argon ions from a room temperature electron beam ion trap

    Institute of Scientific and Technical Information of China (English)

    WANG Tie-Shan; PENG Hai-Bo; Ovsyannikov V P; Kentsch U; Ullmann F; CHENG Rui; Zschornack G

    2008-01-01

    In this work.highly charged ions have been extracted from the advanced Electron Beam Ion Source (EBIS-A) developed in a scientific cooperation between the Dresden University of Technology and the DREEBIT GmbH Dresden.The charge state distributions of ions extracted from the EBIS-A are measured in and extracted in the leaky mode.3×105 Ar18+ ions per pulse are extracted in the pulse mode.The ion charge state distribution is a function of the ionization time.

  19. Study of argon additive in a beam injection type negative ion source using VUV emission spectroscopy

    OpenAIRE

    Nakada, Naoki; Fukumasa, Osamu

    2006-01-01

    Effects of Ar addition are studied by using a beam injection type negative ion source. With adding Ar, I_ increases at low base H_2 pressure. At high base H_2 pressure, however, I_ decreases. VUV emission intensities also decrease at high base pressure. In other words, Ar addition is adverse effect for production of H_2 (v''). Therefore, decrease in I_ is caused by decrease in H_2 (v''). In D_2 plasmas, variation patterns of plasma parameters and VUV intensities by Ar addition are nearly the ...

  20. A continuous microwave discharge maintained by two crossing millimeter-wave beams in hydrogen and argon: numerical simulation and experiment

    Science.gov (United States)

    Chernov, V. V.; Gorbachev, A. M.; Vikharev, A. L.; Radishev, D. B.; Kozlov, A. V.

    2016-12-01

    The results of numerical simulation of a continuous microwave discharge in two crossing wave beams of 30 GHz radiation in a mixture of hydrogen and argon are presented. The model describes the steady state of the gas discharge in Ar-H2-H through the self-consistent solution of the following equations: Maxwell’s equations, the electron balance equation, the transport of hydrogen atoms in the ternary mixture, the heat conduction equation and the equation of state of ideal gas. In Maxwell’s equations the effect of the plasma is taken into account through the conduction current. It is assumed that the generation of electrons occurs due to ionization processes and their loss occurs due to processes of electron-ion recombination and ambipolar diffusion. In the model the heat transfer is considered to be due to gas thermal conductivity and transfer of dissociation energy through the flow of hydrogen atoms. The gas pressure is assumed to be constant, and convection effects are neglected. The other approximations and reductions used in the model are discussed. The adequacy of the obtained model is confirmed by comparing the calculation results to experimental data. For comparison the distributions of gas temperature along the substrate in the center of the discharge and the atomic hydrogen flow to the substrate are used. The temperature is experimentally obtained through the analysis of the optical emission of the C2 Swan line. The atomic hydrogen flow to the substrate is measured from the etching of graphite samples imbedded into the substrate. The possibility of obtaining large-area uniform plasma layers in hydrogen with a small addition of methane is predicted. The applications of such gas discharge are discussed.

  1. 内镜下氩离子凝固术治疗老年人大肠息肉%Endoscopic argon plasma coagulation in the treatment of elderly patients with colorectal polyps

    Institute of Scientific and Technical Information of China (English)

    邵耘; 何晓璞; 吴爱娟; 陈国胜; 许海尘; 薛绮萍; 孙为豪

    2012-01-01

    目的 探讨内镜下氩离子凝固术(APC)治疗老年人大肠息肉的安全性和有效性.方法 采用德国ERBE 公司生产的APC(VI0 200D型)内镜专用氩气刀对电子肠镜检查发现的大肠息肉进行内镜下治疗.结果 258例老年患者共检出525枚息肉全部使用APC治愈,根据息肉大小和形态,使用APC灼除302枚(57.5%),APC切除89枚(17%),黏膜下注射后APC切除134枚(25.5%),局部渗血者行APC电凝或钛夹止血.术后2例(0.8%)出现少量便血,予药物治疗后出血停止,无穿孔和大出血等严重并发症.结论 APC可作为老年人大肠息肉的首选治疗,安全性高,并发症少.%Objective To evaluate the safety and efficacy of endoscopic argon plasma coagulation (APC) in the treatment of elderly patients with colorectal polyps. Methods Colorectal polyps found in electronic enteroscopy were treated with argon plasma generated by ERBE APC (VIO 200D, ERBE Company, German) . Results A total of 525 polyps were detected in 258 elderly patients and all were cured by APC. According to the polyp size and morphology, 302 (57.5%) sessile flat polyps with diameter 0.2 cm to 0.5 cm were ablated with APC, 89 (17%) semi-pedunculated and pedunculated polyps were resected by high-frequency electrosection, and 134 sessile (25.5%) polyps with diameter 0.6 cm to 5.0 cm were resected after submucosal injection with epinephrine plus methylene blue normal saline on focal membrane. APC electric coagulation or titanium clip was employed when bleeding appeared in partial wounds. Minor bleeding occurred in two patients (0.8%) and was stopped after treated with hemostatic drugs; there were no serious complications such as perforations or bleeding requiring transfusion. Conclusion APC is a well tolerated and effective treatment for elderly patients with colorectal polyps.

  2. Combination of Argon Plasma Coagulation and Cryotherapy in Treatment of Central Type Lung Cancer%APC联合冷冻治疗53例中央型肺癌

    Institute of Scientific and Technical Information of China (English)

    王江红; 王珏; 易楠; 项颖

    2009-01-01

    目的 探讨经支气管镜氩等离子体凝固(argon plasma coagulation,APC)结合冷冻治疗中央型肺癌的疗效及安全性.方法 经支气管镜对53例中央型肺癌患者进行APC结合冷冻治疗,其中非小细胞肺癌(NSCLC)46例,小细胞肺癌(SCLC)7例,从症状改善情况、肺功能、血气分析、气促评分、体力状况变化、狭窄再通疗效等方面进行评价.结果 53例病人经136次治疗后完全有效29例(54.7%)、部分有效21例(39.6%)、轻度有效2例(3.8%)、无效1例(1.9%).仅有少数病例出现一过性轻、中度低氧血症(19.9%).结论 经支气管镜应用APC结合冷冻治疗中央型肺癌安全、有效.

  3. Argon plasma coagulation treatment of anal high-grade squamous intraepithelial lesions in men who have sex with men living with HIV: results of a 2-year prospective pilot study.

    Science.gov (United States)

    de Pokomandy, A; Rouleau, D; Lalonde, R; Beauvais, C; de Castro, C; Coutlée, F

    2017-08-23

    Men who have sex with men (MSM) living with HIV are at high risk for anal high-grade squamous intraepithelial lesions (HSILs) and cancer. The best management of anal HSIL remains unclear. Our objective was to assess whether argon plasma coagulation (APC) could be safe, well tolerated and efficient to treat anal HSILs in MSM living with HIV. A prospective phase II, open-label, pilot study was conducted to evaluate APC to treat anal HSILs in 20 HIV-positive MSM. Participants were followed for 2 years after their first treatment. Twenty men with persistent HSILs completed the 2-year study. Their baseline median CD4 count was 490 cells/μL and 85% had undetectable HIV viral loads. Overall, 65% (13/20) of participants were clear of HSILs at their 24-month visit. The initial response rates after the first, second and third APC treatments were 45%, 44% and 67%, respectively, but recurrences were common. The main side effect was pain during and within 1 week after the treatments. There were no long-term side effects, nor serious adverse events related to the procedure. Cost is a drawback. APC can be used to treat anal HSILs in HIV-seropositive MSM, and requires repeated treatment because of a high recurrence rate. As successful treatment of human papillomavirus (HPV) infection or eradication of the anal transitional zone remains impossible, HSIL treatment is challenging and requires long-term follow-up. © 2017 British HIV Association.

  4. Combined electron-beam and coagulation purification of molasses distillery slops. Features of the method, technical and economic evaluation of large-scale facility

    Energy Technology Data Exchange (ETDEWEB)

    Pikaev, A.K. E-mail: pikaev@ipc.rssi.ru; Ponomarev, A.V.; Bludenko, A.V.; Minin, V.N.; Elizar' eva, L.M

    2001-04-01

    The paper summarizes the results obtained from the study on combined electron-beam and coagulation method for purification of molasses distillery slops from distillery produced ethyl alcohol by fermentation of grain, potato, beet and some other plant materials. The method consists in preliminary mixing of industrial wastewater with municipal wastewater, electron-beam treatment of the mixture and subsequent coagulation. Technical and economic evaluation of large-scale facility (output of 7000 m{sup 3} day{sup -1}) with two powerful cascade electron accelerators (total maximum beam power of 400 kW) for treatment of the wastewater by the above method was carried out. It was calculated that the cost of purification of the wastes is equal to 0.25 US$ m{sup -3} that is noticeably less than in the case of the existing method.

  5. Combined electron-beam and coagulation purification of molasses distillery slops. Features of the method, technical and economic evaluation of large-scale facility

    Science.gov (United States)

    Pikaev, A. K.; Ponomarev, A. V.; Bludenko, A. V.; Minin, V. N.; Elizar'eva, L. M.

    2001-04-01

    The paper summarizes the results obtained from the study on combined electron-beam and coagulation method for purification of molasses distillery slops from distillery produced ethyl alcohol by fermentation of grain, potato, beet and some other plant materials. The method consists in preliminary mixing of industrial wastewater with municipal wastewater, electron-beam treatment of the mixture and subsequent coagulation. Technical and economic evaluation of large-scale facility (output of 7000 m 3 day -1) with two powerful cascade electron accelerators (total maximum beam power of 400 kW) for treatment of the wastewater by the above method was carried out. It was calculated that the cost of purification of the wastes is equal to 0.25 US$ m -3 that is noticeably less than in the case of the existing method.

  6. Safety and efficacy of argon plasma coagulator ablation therapy for flat colorectal adenomas Seguridad y eficacia de la ablación de pólipos colorrectales con argón plasma

    Directory of Open Access Journals (Sweden)

    A. García

    2004-05-01

    Full Text Available Introduction: argon-plasma coagulation (APC has been used safely and efficaciously in multiple settings including colon polyp treatment. The aim of this study was to evaluate APC efficacy and safety in the treatment of flat colorectal adenomas. Materials and methods: APC ablation was prospectively performed and evaluated in 22 consecutive patients with colorectal adenomas, 11 of which had large sessile adenomas that were treated with piecemeal polypectomy and APC ablation of residual adenomatous tissue, whereas the remaining eleven patients with flat or carpet-like adenomas were only treated with APC. The mean initial longitudinal extension of adenomas to be treated with APC was 22 mm (range, 20 to 40 mm. Results: the mean age of patients was 70 years. Adenomas were found most frequently in the rectum (50% and cecum (23%. Complete ablation was achieved in 90.9% of adenomas. Recurrence was observed in 20% of patients, all of them in the rectum, after a mean follow-up period of 16.3 months (range, 8 to 35. All recurrences were managed satisfactorily. No major complications were seen. Conclusions: argon plasma coagulator ablation of flat colorectal adenomas is an efficacious and safe technique, specially in the right colon, but results must be confirmed in controlled trials with a higher number of patients.Introducción: el argón plasma (AP, como terapia endoscópica, ha sido utilizado en diferentes lesiones digestivas, incluyendo la ablación de tejido adenomatoso de pólipos colorrectales. El objetivo del presente estudio fue evaluar la seguridad y efectividad del tratamiento con AP de pólipos colorrectales. Material y métodos: se valoró de forma prospectiva la aplicación en la práctica clínica de AP en el tratamiento de 22 pacientes con pólipos colorrectales, de los cuales 11 pacientes con pólipos de gran tamaño fueron tratados con polipectomía endoscópica fragmentada más ablación del tejido adenomatoso con AP, y los otros 11

  7. 氩离子凝固术治疗结直肠息肉的临床应用价值%Application value of curing colorectal polyps with the argon plasma coagulation

    Institute of Scientific and Technical Information of China (English)

    张兰霞; 张鸣青; 王爱民

    2012-01-01

    Objective To evaluate the efficacy and the clinical value of argon plasma coagulation ( APC) in the treatment of colorectal polyps. Methods One hundred and sixty patients with 351 colorectal polyps were treated with APC ablation. 214 sessile and 65 semi-pedunculated polyps were only treated with APC, 72 pedunculated polyps were treated with polypectomy and polyp remnants were also treated with APC. Results All of the patients were healed. Symptomless emphysema under the local mucosal occurred in 2 patients. Transient mild abdominal pain occurred in 78 patients and relieved without treatment. Conclusion APC is an effective and safe method for treating colorectal polyp. It is easy to operate with fewer complications and can be the preferred method for the applanate and wide outsole polyps.%目的 探讨氩离子凝固术治疗结直肠息肉的疗效及临床应用价值.方法 对160例患者共351枚结直肠息肉行氩离子凝固术(APC)治疗,其中214枚扁平和65枚亚蒂息肉仅行APC治疗,72枚有蒂息肉电切治疗后用APC处理息肉残端.结果 本组病例全部临床治愈.2例患者出现无症状的局部黏膜下气肿,78例患者出现短暂腹痛,未行处理自行缓解.结论 APC是一种安全有效的结直肠息肉治疗方法,副反应少,操作简便,尤其是在扁平、广基息肉的治疗中可作为首选方法.

  8. Expression of cyclooxygenase-2 in the mucosa of the gastroesophageal junction in patients with Barrett’s oesophagus – the results of ablation therapy with argon plasma coagulation and laparoscopic Nissen fundoplication

    Directory of Open Access Journals (Sweden)

    Kazimierz Rembiasz

    2010-06-01

    Full Text Available Introduction: Barrett’s oesophagus (BE is a result of replacement of the mucosa of the distal oesophagus by metaplasticcolumnar epithelium. The role of cyclooxygenase-2 (COX-2 and chronic inflammation in the progression of BEtoward adenocarcinoma of the oesophagus is emphasized. Argon plasma coagulation (APC allows for effective ablationof metaplastic mucosa. It is believed that effective suppression of gastric secretion with proton pump inhibitors(PPI promotes squamous cell re-epithelialization and a decrease in expression of some biomarkers including COX-2.A similar effect can be achieved by the anti-reflux procedure.Aim: To evaluate the usefulness of COX-2 expression in determining the risk of malignant transformation in patientswith BE.Material and methods: Patients from two out of three study groups underwent APC ablation of metaplastic mucosacombined with chronic PPI administration (group A or laparoscopic Nissen fundoplication (group B. Controls (group Kwere submitted only to PPI treatment. Expression of COX-2 was evaluated in fresh-frozen biopsy specimens obtainedfrom the distal oesophagus in all 60 patients before and 12 months after treatment.Results: Overexpression of COX-2 was found in 41 patients (68.3%. The highest degree of COX-2 expression was documentedin patients with dysplasia. After treatment overexpression of COX-2 was markedly reduced in patients fromgroups A and B, which correlated well with histopathological findings. Controls did not show important changes inCOX-2 expression.Conclusions: Significant correlation of the degree of COX-2 overexpression with histopathological findings points tothe possible use of this biomarker as a valuable indicator of the risk of malignant transformation in patients with BE.

  9. Argon in action

    CERN Document Server

    Corinne Pralavorio

    2015-01-01

    Over the past few days, the SPS has been accelerating argon ions, which have started to be sent to the NA61/SHINE experiment. This operating mode, using a new type of ion, required a number of modifications to the accelerator.   Picture 1: a “super-cycle” of the SPS, featuring a proton cycle for the LHC, followed by an argon ion cycle for the North Area. Today, the accelerators are once again juggling particles and even performing completely new tricks. The SPS is supplying beams of argon ions for the first time, at energies never before achieved for this type of beam. They are destined for the NA61/SHINE experiment (see box) located in the North Area, which began receiving the beams on 11 February. Argon ions have a relatively large mass, as they consist of 40 nucleons, so they can be used in a similar way to lead ions. The main difficulty in accelerating them lies in the SPS, where the variation in acceleration frequency is limited. “The SPS was designed for a...

  10. Protective Sliding Carbon-Based Nanolayers Prepared by Argon or Nitrogen Ion-Beam Assisted Deposition on Ti6Al4V Alloy

    Directory of Open Access Journals (Sweden)

    Petr Vlcak

    2016-01-01

    Full Text Available The microstructure and the surface properties of samples coated by carbon-based nanolayer were investigated in an effort to increase the surface hardness and reduce the coefficient of friction of the Ti6Al4V alloy. Protective carbon-based nanolayers were fabricated by argon or nitrogen ion-beam assisted deposition at ion energy of 700 eV on Ti6Al4V substrates. The Raman spectra indicated that nanolayers had a diamond-like carbon character with sp2 rich bonds. The TiC and TiN compounds formed in the surface area were detected by X-ray diffraction. Nanoscratch tests showed increased adhesion of a carbon-based nanolayer deposited with ion assistance in comparison with a carbon nanolayer deposited without ion assistance. The results showed that argon ion assistance leads to greater nanohardness than a sample coated by a carbon-based nanolayer with nitrogen ion assistance. A more than twofold increase in nanohardness and a more than fivefold decrease in the coefficient of friction were obtained for samples coated by a carbon-based nanolayer with ion assistance, in comparison with the reference sample.

  11. Crossed-beam time-of-flight study of metastable helium in collisions with helium, neon and argon

    Energy Technology Data Exchange (ETDEWEB)

    Fiering, K.B.; Ryan, S.R. (Arizona Univ., Tucson (USA). Dept. of Physics); Wing, W.H. (Arizona Univ., Tucson (USA). Dept. of Physics; Arizona Univ., Tucson (USA). Optical Sciences Center)

    1982-11-14

    Absolute velocity-resolved total integral cross sections have been measured for collisions of helium singlet (2/sup 1/S/sub 0/) and triplet (2/sup 3/S/sub 1/) metastable (He*) atoms with ground-state helium, neon, and argon atoms in the thermal velocity range of 1.0-3.5x10/sup 5/ cms/sup -1/. Additional measurements on the He*-Ne system with a large input aperture at the detector to suppress the sensitivity of the apparatus to elastic scattering failed to show the previously predicted sharply rising velocity structure in the inelastic excitation transfer cross sections.

  12. Simulation of the CERN GTS-LHC ECR ion source extraction system with lead and argon ion beams

    CERN Document Server

    Toivanen, V; Küchler, D; Lombardi, A; Scrivens, R; Stafford-Haworth, J

    2014-01-01

    A comprehensive study of beam formation and beam transport has been initiated in order to improve the performance of the CERN heavy ion injector, Linac3. As part of this study, the ion beam extraction system of the CERN GTS-LHC 14.5 GHz Electron Cyclotron Resonance Ion Source (ECRIS) has been modelled with the ion optical code IBSimu. The simulations predict self-consistently the triangular and hollow beam structures which are often observed experimentally with ECRIS ion beams. The model is used to investigate the performance of the current extraction system and provides a basis for possible future improvements. In addition, the extraction simulation provides a more realistic representation of the initial beam properties for the beam transport simulations, which aim to identify the performance bottle necks along the Linac3 low energy beam transport. The results of beam extraction simulations with Pb and Ar ion beams from the GTS-LHC will be presented and compared with experimental observations.

  13. Clinical analysis of effect of endoscopic cryotherapy and argon plasma coagulation on 28 cases of Bronchial Tuberculosis%经支气管镜冷冻联合氩气刀治疗支气管结核28例临床分析

    Institute of Scientific and Technical Information of China (English)

    苗玉昴; 齐曼古力·吾守尔; 胡昕; 夏宇; 王晶

    2012-01-01

    Objective To approach the effectiveness of effect of endoscopic cryotherapy and argon plasma coagulation on airway constriction in 28 cases of Bronchial Tuberculosis. Methods 28 cases of airway constriction with Bronchial Tuberculosis received endo scopic cryotherapy and argon plasma coagulation, and clinical symptoms, iconography and endoscopic changes were compared before and alter treatment. Results Every patient underwent 4. 7 times cryotherapy and argon plasma coagulation in the mean course of 1 . 6 months. Rate of complete response, partial response, mild response and invalidity were respectively 57. 1% ( 16/28 ), 35.7% ( 10/28 ), 7.1% ( 2/28 ) and 0. Only two of them was Pneumothorax and the rest of them had no adverse reaction. After 1 ~ 4 months of follow - up , re -stenosis occurred in 4 cases and received stent implantation. Long - term efficiency was 71 A% ( 20/28 ). Conclusions Endoscopic cry otherapy and argon plasma coagulation on airway constriction in treatment of Bronchial Tuberculosis are simple, effective and sale.%目的 探讨经支气管镜介入冷冻联合氩气刀治疗结核性大气道狭窄的疗效.方法 对28例支气管结核患者的狭窄气道进行冷冻联合氩气刀治疗,比较治疗前后的临床表现、影像学及镜下改变等指标来进行疗效评价.结果 28例患者经过平均1.6个月和平均4.7次/人的治疗,完全有效57.1%(16/28),部分有效35.7%(10/28),轻度有效7.1%(2/28),无效0例.术中有2例出现气胸,其余的未见明显不良反应,经过1~4月的随访,4例出现再次狭窄而采取支架植入治疗,长期有效率达71.4%(20/28).结论 冷冻联合氩气刀治疗支气管结核是一项安全、有效、简便的支气管治疗方法.

  14. Efficacy of Argon Plasma Coagulation in Management of Different Pathologic Types Colorectal Polyps%氩离子凝固术治疗不同病理类型结直肠息肉的疗效观察

    Institute of Scientific and Technical Information of China (English)

    赵曙光; 王旭霞; 黄裕新; 闻勤生; 赵保民

    2008-01-01

    目的:氩离子凝固术(Argon-plasma coagulation,APC)可以有效地治疗结直肠息肉,对不同病理类型息肉的疗效是否存在差异,目前尚不清楚.本文比较APC治疗不同病理类型结直肠息肉的效果.方法:对62例结直肠息肉患者共112枚结肠息肉行APC治疗,其中17例亚蒂和74例扁平息肉仅用APC治疗;21例有蒂息肉电切治疗后用APC处理息肉残基,治疗结束后1个月进行结肠镜随访.结果:112枚结直肠息肉经一次APC治疗均成功清除,随访期间共有4例(6.5%)患者出现复发,均为直肠腺瘤性息肉,经再次APC治疗后彻底清除.单纯APC治疗组复发3枚(3.3%);电切后用APC处理残端组术后复发1枚(4.7%),两组间复发率无显著差别(P>0.05),腺瘤性息肉的复发率显著高于其他两种病理类型(P<0.05).1例直肠有蒂息肉经圈套器切除后APC处理残端时出现黏膜下气肿,3例患者出现了短暂的腹痛,未经处理缓解,其余患者无特殊并发症.结论:APC是一种安全有效的结直肠息肉治疗方法,但对腺瘤性息肉APC治疗后应加强随访,以确保治疗成功.

  15. Ambient air particle transport into the effluent of a cold atmospheric-pressure argon plasma jet investigated by molecular beam mass spectrometry

    Science.gov (United States)

    Dünnbier, M.; Schmidt-Bleker, A.; Winter, J.; Wolfram, M.; Hippler, R.; Weltmann, K.-D.; Reuter, S.

    2013-10-01

    Ambient air species, which are transported into the active effluent of an atmospheric-pressure plasma jet result in highly reactive oxygen and nitrogen species (RONS). Especially for the envisaged application field of plasma medicine, these RONS are responsible for strong biological responses. In this work, the effect of ambient air transport into the effluent of an atmospheric-pressure plasma argon jet on the on-axis densities of nitrogen, oxygen and argon was investigated by means of absolutely calibrated molecular beam mass spectrometry (MBMS). According to biomedical experiments a (bottomless) Petri dish was installed in front of the MBMS. In the following, the near flow field is referring to the region close to the nozzle exit and the far flow field is referring to the region beyond that. The absolute on-axis densities were obtained by three different methods, for the near flow field with VUV-absorption technique, for the far flow field with the MBMS and the total flow field was calculated with a computational fluid dynamics (CFD) simulation. The results of the ambient air particle densities of all independent methods were compared and showed an excellent agreement. Therefore the transport processes of ambient air species can be measured for the whole effluent of an atmospheric-pressure plasma jet. Additionally, with the validation of the simulation it is possible in future to calculate the ambient species transport for various gas fluxes in the same turbulent flow regime. Comparing the on-axis densities obtained with an ignited and with a non-ignited plasma jet shows that for the investigated parameters, the main influence on the ambient air species transport is due to the increased temperature in the case when the jet is switched on. Moreover, the presence of positive ions (e.g. ArN_{2}^{+} ) formed due to the interaction of plasma-produced particles and ambient air species, which are transported into the effluent, is shown.

  16. Photon reconstruction in the ATLAS Inner Detector and Liquid Argon Barrel Calorimeter at the 2004 Combined Test Beam

    CERN Document Server

    Abat, E; Addy, T N; Adragna, P; Aharrouche, M; Ahmad, A; Akesson, T.P A; Aleksa, M; Alexa, C; Anderson, K; Andreazza, A; Anghinolfi, F; Antonaki, A; Arabidze, G; Arik, E; Atkinson, T; Baines, J; Baker, O K; Banfi, D; Baron, S; Barr, A J; Beccherle, R; Beck, H P; Belhorma, B; Bell, P J; Benchekroun, D; Benjamin, D P; Benslama, K; Bergeaas Kuutmann, E; Bernabeu, J; Bertelsen, H; Binet, S; Biscarat, C; Boldea, V; Bondarenko, V G; Boonekamp, M; Bosman, M; Bourdarios, C; Broklova, Z; Burckhart-Chromek, D; Bychkov, V; Callahan, J; Calvet, D; Canneri, M; Capeans Garrido, M; Caprini, M; Cardiel Sas, L; Carli, T; Carminati, L; Carvalho, J; Cascella, M; Castillo, M V; Catinaccio, A; Cauz, D; Cavalli, D; Cavalli-Sforza, M; Cavasinni, V; Cetin, S A; Chen, H; Cherkaoui, R; Chevalier, L; Chevallier, F; Chouridou, S; Ciobotaru, M; Citterio, M; Clark, A; Cleland, B; Cobal, M; Cogneras, E; Conde Muino, P; Consonni, M; Constantinescu, S; Cornelissen, T; Correard, S; Corso-Radu, A; Costa, G; Costa, M J; Costanzo, D; Cuneo, S; Cwetanski, P; Da Silva, D; Dam, M; Dameri, M; Danielsson, H O; Dannheim, D; Darbo, G; Davidek, T; De, K; Defay, P O; Dekhissi, B; Del Peso, J; Del Prete, T; Delmastro, M; Derue, F; Di Ciaccio, L; Di Girolamo, B; Dita, S; Dittus, F; Djama, F; Djobava, T; Dobos, D; Dobson, M; Dolgoshein, B A; Dotti, A; Drake, G; Drasal, Z; Dressnandt, N; Driouchi, C; Drohan, J; Ebenstein, W L; Eerola, P; Efthymiopoulos, I; Egorov, K; Eifert, T F; Einsweiler, K; El Kacimi, M; Elsing, M; Emelyanov, D; Escobar, C; Etienvre, A I; Fabich, A; Facius, K; Idrissi Fakhr-Eddine, A; Fanti, M; Farbin, A; Farthouat, P; Fassouliotis, D; Fayard, L; Febbraro, R; Fedin, O L; Fenyuk, A; Fergusson, D; Ferrari, P; Ferrari, R; Ferreira, B C; Ferrer, A; Ferrere, D; Filippini, G; Flick, T; Fournier, D; Francavilla, P; Francis, D; Froeschl, R; Froidevaux, D; Fullana, E; Gadomski, S; Gagliardi, G; Gagnon, P; Gallas, M; Gallop, B J; Gameiro, S; Gan, K K; Garcia, R; Garcia, C; Gavrilenko, I L; Gemme, C; Gerlach, P; Ghodbane, N; Giakoumopoulou, V; Giangiobbe, V; Giokaris, N; Glonti, G; Gottfert, T.; Golling, T; Gollub, N; Gomes, A; Gomez, M D; Gonzalez-Sevilla, S; Goodrick, M J; Gorfine, G; Gorini, B; Goujdami, D; Grahn, K J; Grenier, P; Grigalashvili, N; Grishkevich, Y; Grosse-Knetter, J; Gruwe, M; Guicheney, C; Gupta, A; Haeberli, C; Hartel, R.; Hajduk, Z; Hakobyan, H; Hance, M; Hansen, J D; Hansen, P H; Hara, K; Harvey, A., Jr; Hawkings, R J; Heinemann, F.E W; Henriques Correia, A; Henss, T; Hervas, L; Higon, E; Hill, J C; Hoffman, J; Hostachy, J Y; Hruska, I; Hubaut, F; Huegging, F; Hulsbergen, W; Hurwitz, M; Iconomidou-Fayard, L; Jansen, E; Jen-La Plante, I; Johansson, P.D C; Jon-And, K; Joos, M; Jorgensen, S; Joseph, J; Kaczmarska, A; Kado, M; Karyukhin, A; Kataoka, M; Kayumov, F; Kazarov, A; Keener, P T; Kekelidze, G D; Kerschen, N; Kersten, S; Khomich, A; Khoriauli, G; Khramov, E; Khristachev, A; Khubua, J; Kittelmann, T H; Klingenberg, R; Klinkby, E B; Kodys, P; Koffas, T; Kolos, S; Konovalov, S P; Konstantinidis, N; Kopikov, S; Korolkov, I; Kostyukhin, V; Kovalenko, S; Kowalski, T Z; Kruger, K.; Kramarenko, V; Kudin, L G; Kulchitsky, Y; Lacasta, C; Lafaye, R; Laforge, B; Lampl, W; Lanni, F; Laplace, S; Lari, T; Le Bihan, A C; Lechowski, M; Ledroit-Guillon, F; Lehmann, G; Leitner, R; Lelas, D; Lester, C G; Liang, Z; Lichard, P; Liebig, W; Lipniacka, A; Lokajicek, M; Louchard, L; Loureiro, K F; Lucotte, A; Luehring, F; Lund-Jensen, B; Lundberg, B; Ma, H; Mackeprang, R; Maio, A; Maleev, V P; Malek, F; Mandelli, L; Maneira, J; Mangin-Brinet, M; Manousakis, A; Mapelli, L; Marques, C; Marti i Garcia, S; Martin, F; Mathes, M; Mazzanti, M; McFarlane, K W; McPherson, R; Mchedlidze, G; Mehlhase, S; Meirosu, C; Meng, Z; Meroni, C; Mialkovski, V; Mikulec, B; Milstead, D; Minashvili, I; Mindur, B; Mitsou, V A; Moed, S; Monnier, E; Moorhead, G; Morettini, P; Morozov, S V; Mosidze, M; Mouraviev, S V; Moyse, E.W J; Munar, A; Myagkov, A; Nadtochi, A V; Nakamura, K; Nechaeva, P; Negri, A; Nemecek, S; Nessi, M; Nesterov, S Y; Newcomer, F M; Nikitine, I; Nikolaev, K; Nikolic-Audit, I; Ogren, H; Oh, S H; Oleshko, S B; Olszowska, J; Onofre, A; Padilla Aranda, C; Paganis, S; Pallin, D; Pantea, D; Paolone, V; Parodi, F; Parsons, J; Parzhitski, S; Pasqualucci, E; Passmore, S M; Pater, J; Patrichev, S; Peez, M; Perez Reale, V; Perini, L; Peshekhonov, V D; Petersen, J; Petersen, T C; Petti, R; Phillips, P W; Pilcher, J; Pina, J; Pinto, B; Podlyski, F; Poggioli, L; Poppleton, A; Poveda, J; Pralavorio, P; Pribyl, L; Price, M J; Prieur, D; Puigdengoles, C; Puzo, P; Ragusa, F; Rajagopalan, S; Reeves, K; Reisinger, I; Rembser, C; Bruckman de Renstrom, P.A.; Reznicek, P; Ridel, M; Risso, P; Riu, I; Robinson, D; Roda, C; Roe, S; Rohne, O.; Romaniouk, A; Rousseau, D; Rozanov, A; Ruiz, A; Rusakovich, N; Rust, D; Ryabov, Y F; Ryjov, V; Salto, O; Salvachua, B; Salzburger, A; Sandaker, H; Santamarina Rios, C.Santamarina; Santi, L; Santoni, C; Saraiva, J G; Sarri, F; Sauvage, G; Says, L P; Schaefer, M; Schegelsky, V A; Schiavi, C; Schieck, J; Schlager, G; Schlereth, J; Schmitt, C; Schultes, J; Schwemling, P; Schwindling, J; Seixas, J M; Seliverstov, D M; Serin, L; Sfyrla, A; Shalanda, N; Shaw, C; Shin, T; Shmeleva, A; Silva, J; Simion, S; Simonyan, M; Sloper, J E; Smirnov, S.Yu; Smirnova, L; Solans, C; Solodkov, A; Solovianov, O; Soloviev, I; Sosnovtsev, V V; Spano, F; Speckmayer, P; Stancu, S; Stanek, R; Starchenko, E; Straessner, A; Suchkov, S I; Suk, M; Szczygiel, R; Tarrade, F; Tartarelli, F; Tas, P; Tayalati, Y; Tegenfeldt, F; Teuscher, R; Thioye, M; Tikhomirov, V O; Timmermans, C.J.W P; Tisserant, S; Toczek, B; Tremblet, L; Troncon, C; Tsiareshka, P; Tyndel, M; Karagoz Unel, M.; Unal, G; Unel, G; Usai, G; Van Berg, R; Valero, A; Valkar, S; Valls, J A; Vandelli, W; Vannucci, F; Vartapetian, A; Vassilakopoulos, V I; Vasilyeva, L; Vazeille, F; Vernocchi, F; Vetter-Cole, Y; Vichou, I; Vinogradov, V; Virzi, J; Vivarelli, I; de Vivie, J B; Volpi, M; Vu Anh, T; Wang, C; Warren, M; Weber, J; Weber, M; Weidberg, A R; Weingarten, J; Wells, P S; Werner, P; Wheeler, S; Wiesmann, M; Wilkens, H; Williams, H H; Wingerter-Seez, I; Yasu, Y; Zaitsev, A; Zenin, A; Zenis, T; Zenonos, Z; Zhang, H; Zhelezko, A; Zhou, N

    2011-01-01

    The reconstruction of photons in the ATLAS detector is studied with data taken during the 2004 Combined Test Beam, where a full slice of the ATLAS detector was exposed to beams of particles of known energy at the CERN SPS. The results presented show significant differences in the longitudinal development of the electromagnetic shower between converted and unconverted photons as well as in the total measured energy. The potential to use the reconstructed converted photons as a means to precisely map the material of the tracker in front of the electromagnetic calorimeter is also considered. All results obtained are compared with a detailed Monte-Carlo simulation of the test-beam setup which is based on the same simulation and reconstruction tools as those used for the ATLAS detector itself.

  17. Proton Scattering on Liquid Argon

    Science.gov (United States)

    Bouabid, Ryan; LArIAT Collaboration

    2017-01-01

    LArIAT (Liquid Argon In A Test-beam) is a liquid argon time projection chamber (LArTPC) positioned in a charged particle beamline whose primary purpose is to study the response of LArTPC's to charged particle interactions. This previously unmeasured experimental data will allow for improvement of Monte Carlo simulations and development of identification techniques, important for future planned LArTPC neutrino experiments. LArIAT's beamline is instrumented to allow for the identification of specific particles as well as measurement of those particles' incoming momenta. Among the particles present in the beamline, the analysis presented here focuses on proton-Argon interactions. This study uses particle trajectories and calorimetric information to identify proton-Argon interaction candidates. We present preliminary data results on the measurement of the proton-Argon cross-section. Liquid Argon In A Test Beam. The work is my analysis made possible through the efforts of LArIAT detector, data, and software.

  18. Proposal for a Full-Scale Prototype Single-Phase Liquid Argon Time Projection Chamber and Detector Beam Test at CERN

    CERN Document Server

    Kutter, T

    2015-01-01

    The Deep Underground Neutrino Experiment (DUNE) will use a large liquid argon (LAr) detector to measure the CP violating phase, determine the neutrino mass hier- archy and perform precision tests of the three-flavor paradigm in long-baseline neutrino oscillations. The detector will consist of four modules each with a fiducial mass of 10 kt of LAr and due to its unprecedented size will allow sensitive searches for proton decay and the detection and measurement of electron neutrinos from core collapse supernovae [1]. The first 10 kt module will use single-phase LAr detection technique and be itself modular in design. The successful manufacturing, installation and operation of several full-scale detector components in a suitable configuration represents a critical engineering milestone prior to the construction and operation of the first full 10 kt DUNE detector module at the SURF underground site. A charged particle beam test of a prototype detector will provide critical calibration measurements as well as inva...

  19. Analysis of a Partial Male-Sterile Mutant of Arabidopsis thaliana Isolated from a Low-Energy Argon Ion Beam Mutagenized Pool

    Institute of Scientific and Technical Information of China (English)

    XU Min; BIAN Po; WU Yuejin; YU Zengliang

    2008-01-01

    A screen for Arabidopsis fertility mutants, mutagenized by low-energy argon ion beam, yielded two partial male-sterile mutants tc243-1 and tc243-2 which have similar phenotypes. tc243-2 was investigated in detail. The segregation ratio of the mutant phenotypes in the M2 pools suggested that mutation behaved as single Mendelian recessive mutations, tc243 showed a series of mutant phenotypes, among which partial male-sterile was its striking mutant characteristic. Phenotype analysis indicates that there are four factors leading to male sterility, a. Floral organs normally develop inside the closed bud, but the anther filaments do not elongate sufficiently to position the locules above the stigma at anthesis, b. The anther locules do not dehisce at the time of flower opening (although limited dehiscence occurs later), c. Pollens of mutant plants develop into several types of pollens at the trinucleated stage, as determined by staining with DAPI (4',6-diamidino-2-phenylindole), which shows a variable size, shape and number of nucleus. d. The viability of pollens is lower than that of the wild type on the germination test in vivo and vitro.

  20. Reactive ion beam etching studies of tungsten with CF sub 4 /argon mixtures using ion scattering spectroscopy and SIMS

    Energy Technology Data Exchange (ETDEWEB)

    Cox, T.I.; Deshmukh, V.G.I. (Royal Signals and Radar Establishment, Malvern (UK)); Armour, D.G. (Salford Univ. (UK). Dept. of Electrical Engineering)

    1989-01-01

    Tungsten foil was bombarded at 550 eV with ion beams generated from CF{sub 4}/Ar gas mixtures. The chemical compositions of the bombarded surface and etch products were determined using Ion Scattering Spectroscopy and Secondary Ion Mass Spectrometry respectively. As the ratio CF{sub 4}/Ar was increased, the tungsten surface became covered with fluorine atoms. The products observed were positive ions of W, WF, and WF{sub 2}, with WF{sub 2} being only formed above a threshold concentration of CF{sub 4} in the gas mixture. (author).

  1. Fabrication and characterization of tunnel barriers in a multi-walled carbon nanotube formed by argon atom beam irradiation

    Energy Technology Data Exchange (ETDEWEB)

    Tomizawa, H. [Advanced Device Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Department of Applied Physics, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585 (Japan); Yamaguchi, T., E-mail: tyamag@riken.jp [Advanced Device Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Akita, S. [Department of Physics and Electronics, Osaka Prefecture University, 1-1 Gakuen-cho, Nakaku, Sakai, Osaka 599-8531 (Japan); Ishibashi, K. [Advanced Device Laboratory, RIKEN, 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan); Department of Applied Physics, Tokyo University of Science, 6-3-1 Niijuku, Katsushika-ku, Tokyo 125-8585 (Japan); RIKEN Center for Emergent Matter Science (CEMS), 2-1 Hirosawa, Wako, Saitama 351-0198 (Japan)

    2015-07-28

    We have evaluated tunnel barriers formed in multi-walled carbon nanotubes (MWNTs) by an Ar atom beam irradiation method and applied the technique to fabricate coupled double quantum dots. The two-terminal resistance of the individual MWNTs was increased owing to local damage caused by the Ar beam irradiation. The temperature dependence of the current through a single barrier suggested two different contributions to its Arrhenius plot, i.e., formed by direct tunneling through the barrier and by thermal activation over the barrier. The height of the formed barriers was estimated. The fabrication technique was used to produce coupled double quantum dots with serially formed triple barriers on a MWNT. The current measured at 1.5 K as a function of two side-gate voltages resulted in a honeycomb-like charge stability diagram, which confirmed the formation of the double dots. The characteristic parameters of the double quantum dots were calculated, and the feasibility of the technique is discussed.

  2. Efficacy and safety of argon plasma coagulation for the treatment of hemorrhagic radiation proctitis Eficacia y seguridad de la electrocoagulación con plasma de argón en el tratamiento del sangrado rectal secundario a proctitis por radioterapia

    Directory of Open Access Journals (Sweden)

    C. de la Serna Higuera

    2004-11-01

    Full Text Available Objective: to evaluate the efficacy, safety and medium-/long-term clinical course of patients undergoing endoscopic treatment with argon plasma coagulation for hemorrhagic radiation proctopathy. Design: descriptive, retrospective study with medium- and long-term follow-up. Patients, material and methods: ten patients were treated with argon plasma coagulation for hemorrhagic radiation proctopathy between July 1998 and February 2003. Inclusion criteria were: evidence of chronic rectal bleeding, consistent endoscopic findings, and absence of any other cause of hematochezia after a comprehensive ano-rectal examination and complete colonoscopy. The equipment used was a standard colonoscope, an argon delivery unit, an argon plasma coagulation probe 1.5 mm in internal diameter, and a high-frequency electrosurgical generator. Consecutive treatment sessions were programmed whenever it was considered necessary until all mucosal lesions had been treated. Clinical and evolutive follow-up was performed with a focus on tolerance, efficacy, and potential argon plasma coagulation-related complications. Data were updated by personal or telephonic interview. Results: in all patients, chronic rectal bleeding stopped after the last treatment session. The mean number of treatment sessions to stop symptoms was 1.7. Mean follow-up was 31.1 months. All sessions were well tolerated, similarly to standard rectoscopy. In one case a recurrence of rectal bleeding was observed four months later, which required two repeat sessions. Four patients were anemic at inclusion. Three of them reported a resolved anemia at the end of the study. No delayed argon plasma coagulation-related complications such us ulcers or strictures were seen. Conclusions: argon plasma coagulation appears to be a useful, effective and safe treatment for rectal bleeding resulting from chronic radiation proctitis when compared to standard medical and endoscopic treatments. These successful outcomes seem

  3. Hemostatic efficacy of TachoSil in liver resection compared with argon beam coagulator treatment: An open, randomized, prospective, multicenter, parallel-group trial

    DEFF Research Database (Denmark)

    Fischer, Lars; Seiler, Christoph M.; Broelsch, Christoph E.

    2011-01-01

    surgical trial with 2 parallel groups. Patients were eligible for intra-operative randomization after elective resection of ≥1 liver segment and primary hemostasis. The primary end point was the time to hemostasis after starting the randomized intervention to obtain secondaty hemostasis. Secondary end...

  4. Hemostatic efficacy of TachoSil in liver resection compared with argon beam coagulator treatment: An open, randomized, prospective, multicenter, parallel-group trial

    DEFF Research Database (Denmark)

    Fischer, Lars; Seiler, Christoph M.; Broelsch, Christoph E.

    2011-01-01

    points were drainage duration, volume, and content. Adverse events were collected to evaluate the safety of treatments. The trial was registered internationally (Eudract number 2008-006407-23). Results: Among 119 patients (60 TachoSil and 59 ABC) randomized in 10 tertiary care centers in Europe, the mean...... time to hemostasis was less when TachoSil was used (3.6 minutes) compared with ABC (5.0 minutes; P = .0018). The estimated ratio of mean time to hemostasis for TachoSil/ABC ws 0.61 (95% confidence interval, 0.47-0.80; P = .0003). Postoperative drainage volume, drainage fluid, and drainage duration did...... not differ between the 2 groups. Mortality (2 vs. 4 patients) and adverse reactions (24 vs. 28 patients) for TachoSil versus ABC did not differ. Conclusion: This trial confirmed that TachoSil achieved significantly faster hemostasis after liver resection compared with ABC. Postoperative morbidity...

  5. Hemostatic efficacy of TachoSil in liver resection compared with argon beam coagulator treatment: an open, randomized, prospective, multicenter, parallel-group trial

    DEFF Research Database (Denmark)

    Fischer, Lars; Seiler, Christoph M; Broelsch, Christoph E;

    2011-01-01

    surgical trial with 2 parallel groups. Patients were eligible for intra-operative randomization after elective resection of = 1 liver segment and primary hemostasis. The primary end point was the time to hemostasis after starting the randomized intervention to obtain secondary hemostasis. Secondary end...... time to hemostasis was less when TachoSil was used (3.6 minutes) compared with ABC (5.0 minutes; P = .0018). The estimated ratio of mean time to hemostasis for TachoSil/ABC was 0.61 (95% confidence interval, 0.47-0.80; P = .0003). Postoperative drainage volume, drainage fluid, and drainage duration did...... not differ between the 2 groups. Mortality (2 vs 4 patients) and adverse reactions (24 vs 28 patients) for TachoSil versus ABC did not differ. CONCLUSION: This trial confirmed that TachoSil achieved significantly faster hemostasis after liver resection compared with ABC. Postoperative morbidity and mortality...

  6. The effect of the dc bias voltage on the x-ray bremsstrahlung and beam intensities of medium and highly charged ions of argon.

    Science.gov (United States)

    Rodrigues, G; Lakshmy, P S; Baskaran, R; Kanjilal, D; Roy, A

    2010-02-01

    X-ray bremsstrahlung measurements from the 18 GHz High Temperature Superconducting Electron Cyclotron Resonance Ion Source, Pantechnik-Delhi Ion Source were measured as a function of negative dc bias voltage, keeping all other source operating parameters fixed and the extraction voltage in the off condition. The optimization of medium and highly charged ions of argon with similar source operating parameters is described. It is observed that the high temperature component of the electron is altered significantly with the help of bias voltage, and the electron population has to be maximized for obtaining higher current.

  7. The scintillation of liquid argon

    CERN Document Server

    Heindl, T; Hofmann, M; Krücken, R; Oberauer, L; Potzel, W; Wieser, J; Ulrich, A

    2015-01-01

    A spectroscopic study of liquid argon from the vacuum ultraviolet at 110 nm to 1000 nm is presented. Excitation was performed using continuous and pulsed 12 keV electron beams. The emission is dominated by the analogue of the so called 2nd excimer continuum. Various additional emission features were found. The time structure of the light emission has been measured for a set of well defined wavelength positions. The results help to interpret literature data in the context of liquid rare gas detectors in which the wavelength information is lost due to the use of wavelength shifters.

  8. LIQUID ARGON CALORIMETER PERFORMANCE AT HIGH RATES

    CERN Document Server

    Kukhtin, V; The ATLAS collaboration

    2011-01-01

    The performance of the ATLAS liquid argon endcap and forward calorimeters has been projected at the planned high luminosity LHC option HL-LHC by exposing small calorimeter modules of the electromagnetic, hadronic, and forward calorimeters to high intensity proton beams at IHEP/Protvino accelerator. The results of HV current and of pulse shape analysis, and also the dependence of signal amplitude on beam intensity are presented.

  9. Valoración de la respuesta endoscópica al tratamiento con argón plasma en la rectitis actínica crónica Evaluation of the endoscopic response to argon plasma coagulation in patients with chronic radiation proctopathy

    Directory of Open Access Journals (Sweden)

    M. Latorre Sánchez

    2008-10-01

    Full Text Available Objetivo: valorar la mejoría endoscópica tras el tratamiento con argón plasma utilizado para el control sintomático de las rectitis actínicas crónicas. Diseño y pacientes: estudio prospectivo de 48 meses de duración, con 38 pacientes (26 hombres y 12 mujeres, con edad media de 70,9 ± 7,38 años. Todos presentaban algún grado de rectorragia y/o anemia. Se realizaron entrevistas clínicas, analíticas y sesiones endoscópicas con argón, de forma periódica mensual, hasta la normalización analítica y cese del sangrado, con un seguimiento posterior de 24 meses. Para valorar la mejoría se utilizaron parámetros analíticos, gradación de sangrado (Chutckan y un índice endoscópico. Resultados: el tiempo medio trascurrido entre el inicio y la finalización del seguimiento fue de 28,5 ± 3,9 meses. La media de sesiones administradas por paciente ha sido de 3,6 ± 2,7. Si comparamos los síntomas antes, después del tratamiento existe una disminución significativa en el grado de rectorragia según la clasificación de Chutkan (2,29 ± 1,08 vs. 0,59 ± 1,12, p Objectives: to evaluate endoscopic improvement after argon plasma coagulation (APC in symptomatic patients with chronic radiation proctopathy. Methods and patients: a prospective study of 38 patients with radiation proctitis (26 males and 12 females, mean age 70.9 ± 7.38 yrs, and with rectal bleeding and or anemia. We performed monthly interviews, blood tests, and APC sessions until rectal bleeding had ceased and hemoglobin and ferritin levels were improved, with a follow-up of 24 months. We used blood testing, bleeding scores (Chutckhan's index, and endoscopic scores to evaluate improvement. Results: mean time between inclusion and follow-up completion was 28.5 ± 3.9 months. Mean number of sessions per patient was 3.6 ± 2.7. There was a significant decrease (2.29 ± 1.8 vs. 0.59 ± 1.12, p < 0.05 in rectal bleeding (Chutckan score from baseline after APC. There was a significant

  10. Therapeutic effect of argon plasma coagulation and cryotherapy combined with radiotherapy on patients with central type lung cancer%经支气管镜氩等离子体凝固及冷冻结合体外放射联合治疗中央型肺癌疗效的临床研究

    Institute of Scientific and Technical Information of China (English)

    何小鹏; 刘小伟; 党焱; 王利; 杨友文; 朱波; 陈剑辉; 马玉娟

    2013-01-01

    [Objective] To study the efficacy and safety of argon plasma coagulation (APC) and cryotherapy through bronchoscope combined with radiation on patients with central type lung cancer.[Methods] 60 patients with central type lung cancer patients were divided into two groups.35 cases in treatment group,with combined therapy.The control group 25 cases,radiation treatment.Clinical symptom,life quality scroe,airway obstruction were measured before and after treatment.[Results] After average 4 times APC and cryotherapy through bronchoscope,result compared with control group,the remission rate of clinical symptoms,airway obstruction,and improve of life quality score were markedly highter,two group had a statistically difference (P <0.05).[Conclusion] Radiation combined with APC and cryotherapy through bronchoscope is a effective and safe therapy for the patients with central type lung cancer.%目的 探讨经支气管镜氩等离子体凝固(APC)及冷冻技术结合体外放射治疗中央型肺癌的疗效.方法 对35例确诊为中心型肺癌的患者进行联合治疗,并与单纯放疗患者进行对比,以观察其疗效.结果 经平均4次的介入治疗,治疗组临床症状、生活质量评分、气道阻塞的缓解相对于对照组均有明显改善,其差异具有显著性(P<0.05).结论 经支气管镜APC及冷冻技术结合体外放疗是治疗中心型肺癌的安全有效方法.

  11. Experimental and Theoretical Estimation of Excited Species Generation in Pulsed Electron Beam-Generated Plasmas Produced in Pure Argon, Nitrogen, Oxygen, and Their Mixtures

    Science.gov (United States)

    2011-05-13

    efficiency i (-) Oxygen molecules (O2) a1X3 3.8 x 103 1.27 mkm 0.98 b1X3 12 762 1.63 c1 +A,3+A3 0.09 243-306 4.70 B3X3 5 x10-7...published in the 20th centuries: argon NIFS -DATA-72, National Institute for Fusion Science (Jpn), ISSN 0915-6364. 34. C. Yamabe, S. J. Buckman and A. V...contribution of the b1 family of states. DS 6 is the peak observed at 15.8 eV. DS 7 is associated with a state at 17.3 eV. DS 8 is for c1  states

  12. Spatial coagulation with bounded coagulation rate

    OpenAIRE

    Bailleul, Ismael

    2010-01-01

    We prove that the spatial coagulation equation with bounded coagulation rate is well-posed for all times in a given class of kernels if the convection term of the underlying particle dynamics has divergence bounded below by a positive constant. Multiple coagulations, fragmentation and scattering are also considered.

  13. ICARUS and status of liquid argon technology

    CERN Document Server

    Menegolli, Alessandro

    2012-01-01

    ICARUS T600 is the largest liquid Argon Time Projection Chamber (LAr TPC) detector ever realized. It operates underground at the LNGS laboratory in Gran Sasso. It has been smoothly running since summer 2010, collecting data with the CNGS (Cern to Gran Sasso) beam and with cosmic particles. Liquid Argon TPCs are indeed 'electronic bubble chambers', providing a completely uniform imaging calorimetry with unprecedented accuracy on such massive volumes. ICARUS T600 is internationally considered as a milestone towards the realization of the next generation of massive detectors (tens of ktons) for neutrino and rare event physics. Results will be presented on the data collected so far with the detector.

  14. Argon broad ion beam tomography in a cryogenic scanning electron microscope: a novel tool for the investigation of representative microstructures in sedimentary rocks containing pore fluid.

    Science.gov (United States)

    Desbois, G; Urai, J L; Pérez-Willard, F; Radi, Z; Offern, S; Burkart, I; Kukla, P A; Wollenberg, U

    2013-03-01

    The contribution describes the implementation of a broad ion beam (BIB) polisher into a scanning electron microscope (SEM) functioning at cryogenic temperature (cryo). The whole system (BIB-cryo-SEM) provides a first generation of a novel multibeam electron microscope that combines broad ion beam with cryogenic facilities in a conventional SEM to produce large, high-quality cross-sections (up to 2 mm(2)) at cryogenic temperature to be imaged at the state-of-the-art SEM resolution. Cryogenic method allows detecting fluids in their natural environment and preserves samples against desiccation and dehydration, which may damage natural microstructures. The investigation of microstructures in the third dimension is enabled by serial cross-sectioning, providing broad ion beam tomography with slices down to 350 nm thick. The functionalities of the BIB-cryo-SEM are demonstrated by the investigation of rock salts (synthetic coarse-grained sodium chloride synthesized from halite-brine mush cold pressed at 150 MPa and 4.5 GPa, and natural rock salt mylonite from a salt glacier at Qom Kuh, central Iran). In addition, results from BIB-cryo-SEM on a gas shale and Boom Clay are also presented to show that the instrument is suitable for a large range of sedimentary rocks. For the first time, pore and grain fabrics of preserved host and reservoir rocks can be investigated at nm-scale range over a representative elementary area. In comparison with the complementary and overlapping performances of the BIB-SEM method with focused ion beam-SEM and X-ray tomography methods, the BIB cross-sectioning enables detailed insights about morphologies of pores at greater resolution than X-ray tomography and allows the production of large representative surfaces suitable for FIB-SEM investigations of a specific representative site within the BIB cross-section.

  15. 支气管镜介导下氩气刀与氩气刀联合冷冻技术治疗气道狭窄的对照研究%Prospective study of argon plasma coagulation(APC)and cryotherapy combined with APC under bronchoscopy for airway stenosis

    Institute of Scientific and Technical Information of China (English)

    程剑剑; 陈献亮; 张文平; 齐咏; 刘红梅; 马芸

    2011-01-01

    Objective To compare the efficacy and safety of argon plasma coagulation(APC)with cryotherapy combined with APC under flexible bronchoscopy to treat airway stenosis.Methods Patients with inoperable airway stenosis which are suitable for APC treatment are assigned to APC group or APC combined with cryotherapy group randomly.Then,evaluate the effect of the two different therapy by bronchoscopy.Results Fourteen of the total 40 patients have to undergo other therapy such as implanting stents and/or brachytherapy because of their special conditions,6 of them belonging to APC group,8 of them belonging to APC combined with cryotherapy group.Forty patients underwent 127 times of bronchoscopy.No differences in efficacy and safety were discovered between the two groups(P=0.173).Conclusions APC and cryotherapy combined with APC under bronchoscopy for airway stenosis were clinically safe and effective.%目的 评价支气管镜介导下使用氩气刀与联合使用氩气刀及冷冻技术治疗气道狭窄,对比其有效性和安全性.方法 选择2008年7月至2010年4月门诊及住院治疗的气道狭窄患者,根据病因及气道内的镜下表现,判断具有支气管镜介导下氩气刀治疗指征的患者,随机进入氩气刀治疗组或氩气刀联合冷冻治疗组.追踪复查支气管镜,评价疗效.结果 14例患者根据病情需要另外联合支架置入和/或后装放疗,其中6例属氩气刀治疗组,氩气刀联合冷冻治疗组8例.40例患者共进行127次气管镜检查治疗.两组患者疗效相比差异无统计学意义(P=0.173),均未出现并发症.结论 气管镜介导下使用氩气刀与联合使用氩气刀及冷冻技术治疗气道狭窄,均能达到满意的临床疗效,安全可靠.

  16. 高频电刀氩气刀治疗伴呼吸功能不全的大气道肿瘤效果和安全性%Efficacy and safety of electrocautery and argon plasma coagulation for the therapy of central airway tumor with respiratory insufficiency

    Institute of Scientific and Technical Information of China (English)

    周一平; 陈小可; 刘慧; 夏莉萍; 喻海琼; 刘念; 李爱芬; 林海容

    2015-01-01

    目的:探讨经支气管镜高频电刀氩气刀治疗伴呼吸功能不全大气道肿瘤的有效性和安全性。方法分析广东医学院附属福田医院2010年9月~2014年12月19例经病理确诊的伴呼吸功能不全的晚期中央型肺癌患者的高频电刀氩气刀治疗情况。结果19例患者共进行了37次治疗,手术室全麻6人6次,其他31次均在支气管镜室非全麻下手术,25次辅助通气下进行。有效8例,部分有效7例,轻度有效3例。同时进行光动力照射治疗的有6例,置入金属支架的有1例。结论治疗大气道肿瘤伴呼吸功能不全,选择良好的麻醉和呼吸支持方式后,高频电刀氩气刀术是一种安全、有效的方法。%Objective To investigate the efficacy and safety of electrocautery and argon plasma coagulation (APC) for the therapy of central airway tumor with respiratory insufficiency. Methods The efficacy of electrocautery and APC for the therapy of 19 pathologically confirmed advanced central airway tumor with respiratory insufficiency from September 2010 to December 2014 in Affiliated Futian Hospital of Guangdong Medical College was analyzed. Results Of the 19 patients with a total of 37 treatments, 6 patients and 6 periods were in the operating room under general anesthesia;the other 31 periods were in the bronchoscopy room under potical anesthesia with sedation, 25 periods with assisted me-chanical ventilation. 8 cases were effective, 7 cases were partial response, 3 cases were mild effective. 6 cases took si-multaneous photodynamic therapy, one case took metal stent implantation. Conclusion With the proper anesthesia and respiratory support, electrocautery and APC is a safe and effective method for central airway tumor with respiratory in-sufficiency.

  17. ATLAS Liquid Argon Calorimeter Module Zero

    CERN Multimedia

    1993-01-01

    This module was built and tested with beam to validate the ATLAS electromagnetic calorimeter design. One original design feature is the folding. 10 000 lead plates and electrodes are folded into an accordion shape and immersed in liquid argon. As they cross the folds, particles are slowed down by the lead. As they collide with the lead atoms, electrons and photons are ejected. There is a knock-on effect and as they continue on into the argon, a whole shower is produced. The electrodes collect up all the electrons and this signal gives a measurement of the energy of the initial particle. The M0 was fabricated by French institutes (LAL, LAPP, Saclay, Jussieu) in the years 1993-1994. It was tested in the H6/H8 beam lines in 1994, leading to the Technical Design Report in 1996.

  18. A new, very massive modular Liquid Argon Imaging Chamber to detect low energy off-axis neutrinos from the CNGS beam. (Project MODULAr)

    CERN Document Server

    Baibussinov, B; Battistoni, G; Benetti, P; Borio, A; Calligarich, E; Cambiaghi, M; Cavanna, F; Centro, Sandro; Cocco, A G; Dolfini, R; Berzolari, A Gigli; Farnese, C; Fava, A; Ferrari, A; Fiorillo, G; Gibin, D; Guglielmi, A M; Mannocchi, G; Mauri, F; Menegolli, A; Meng, G; Montanari, C; Palamara, O; Periale, L; Piazzoli, A; Picchi, P; Pietropaolo, F; Rappoldi, A; Raselli, G L; Rubbia, Carlo; Sala, P; Satta, G; Varanini, F; Ventura, Sandro; Vignoli, C

    2007-01-01

    The paper is considering an opportunity for the CERN/GranSasso (CNGS) neutrino complex, concurrent time-wise with T2K and NOvA, to search for theta_13 oscillations and CP violation. Compared with large water Cherenkov (T2K) and fine grained scintillators (NOvA), the LAr-TPC offers a higher detection efficiency and a lower backgrounds, since virtually all channels may be unambiguously recognized. The present proposal, called MODULAr, describes a 20 kt fiducial volume LAr-TPC, following very closely the technology developed for the ICARUS-T60o, and is focused on the following activities, for which we seek an extended international collaboration: (1) the neutrino beam from the CERN 400 GeV proton beam and an optimised horn focussing, eventually with an increased intensity in the framework of the LHC accelerator improvement program; (2) A new experimental area LNGS-B, of at least 50000 m3 at 10 km off-axis from the main Laboratory, eventually upgradable to larger sizes. A location is under consideration at about ...

  19. Coagulation for the clinician

    African Journals Online (AJOL)

    on the surface of many cell types that are not normally in contact with the circulation (Fig. ...... The special stationary cylindrical cup holds the blood (0.36 ml) and is oscillated through .... coagulation process. The battery of traditional coagulation.

  20. Coagulation Factors Test

    Science.gov (United States)

    ... be limited. Home Visit Global Sites Search Help? Coagulation Factors Share this page: Was this page helpful? ... else I should know? How is it used? Coagulation factor testing is performed to determine if a ...

  1. Study on tracheal intubation related severe subglottic stenosis under laryngeal mask by using holmium laser combined with argon plasma coagulation and cryotherapy through bronchoscopy%喉罩下经支气管镜钬激光联合氩气刀和二氧化碳冷冻治疗儿童获得性重度声门下狭窄

    Institute of Scientific and Technical Information of China (English)

    许煊; 祝彬; 石苗茜; 任海丽; 封志纯

    2015-01-01

    目的:探讨2例气管插管相关性重度声门下狭窄喉罩下支气管镜诊断及介入治疗的操作方法、有效性及安全性。方法2例男性患儿,年龄分别为4和11个月,因气管插管后出现脱机困难及呼吸困难,经CT及支气管镜检查,诊断为气管插管相关的重度声门下狭窄,在对家长进行详细告知支气管镜下介入手术不可预知情况并由家长签字同意后,遂对2例患儿进行经喉罩支气管镜下钬激光联合氩气刀和二氧化碳( CO2)冷冻治疗,分析患儿的临床资料、并发症及术后转归、随访情况。结果2例手术过程顺利,例1术后紧贴声门下的肉芽组织被完全清除,2例患儿声门下环形狭窄完全解除,治疗前呼吸道狭窄处周长约2.5 mm,治疗后,周长达5.2 mm,4.0 mm支气管镜进出无障碍,术后气管导管均成功拔除,呼吸困难均明显改善。2例患儿治疗后即刻、7 d、30 d和90 d镜下检查结果示狭窄处开放良好。术中有血氧饱和度下降及心率增快或减慢,暂停操作及恢复给氧后立即恢复,术中及术后未见异常血流动力学改变,2例目前仍在随访中。结论经喉罩钬激光、氩气刀及CO2冷冻治疗可用于后天性肉芽组织增生引起的声门下狭窄,方法安全、有效,近期效果显著,远期仍在进一步随访评估。%Objective To explore the operating methods,the effectiveness and safety for 2 cases of tracheal in-tubation related severe subglottic stenosis under laryngeal mask by using bronchoscopy in the diagnosis and interven-tional treatment. Methods Two male patients ( age at 4 and 11 months) both had difficulty breathing and weaning failure after endotracheal intubation,who were diagnosed with severe subglottic stenosis through CT and bronchoscopy examination. All parents signed their consent after being fully informed of treatment risks. Two cases were treated under bronchoscopic holmium laser combined with argon plasma coagulation and

  2. Evidence of room temperature ferromagnetism in argon/oxygen annealed TiO{sub 2} thin films deposited by electron beam evaporation technique

    Energy Technology Data Exchange (ETDEWEB)

    Mohanty, P. [School of Materials Science and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi 221005 (India); Kabiraj, D. [Inter University Accelerator Center, Aruna Asaf Ali Marg, New Delhi 110067 (India); Mandal, R.K. [Department of Metallurgical Engineering, Indian Institute of Technology, Banaras Hindu University, Varanasi 221005 (India); Kulriya, P.K. [Inter University Accelerator Center, Aruna Asaf Ali Marg, New Delhi 110067 (India); Sinha, A.S.K. [Department of Chemical Engineering, Indian Institute of Technology, Banaras Hindu University, Varanasi 221005 (India); Rath, Chandana, E-mail: chandanarath@yahoo.com [School of Materials Science and Technology, Indian Institute of Technology, Banaras Hindu University, Varanasi 221005 (India)

    2014-04-15

    TiO{sub 2} thin films deposited by electron beam evaporation technique annealed in either O{sub 2} or Ar atmosphere showed ferromagnetism at room temperature. The pristine amorphous film demonstrates anatase phase after annealing under Ar/O{sub 2} atmosphere. While the pristine film shows a super-paramagnetic behavior, both O{sub 2} and Ar annealed films display hysteresis at 300 K. X-ray photo emission spectroscopy (XPS), Raman spectroscopy, Rutherford’s backscattering spectroscopy (RBS), cross-sectional transmission electron microscopy (TEM) and energy dispersive X-ray spectroscopy (EDS) were used to refute the possible role of impurities/contaminants in magnetic properties of the films. The saturation magnetization of the O{sub 2} annealed film is found to be higher than the Ar annealed one. It is revealed from shifting of O 1s and Ti 2p core level spectra as well as from the enhancement of high binding energy component of O 1s spectra that the higher magnetic moment is associated with higher oxygen vacancies. In addition, O{sub 2} annealed film demonstrates better crystallinity, uniform deposition and smoother surface than that of the Ar annealed one from glancing angle X-ray diffraction (GAXRD) and atomic force microscopy (AFM). We conclude that although ferromagnetism is due to oxygen vacancies, the higher magnetization in O{sub 2} annealed film could be due to crystallinity, which has been observed earlier in Co doped TiO{sub 2} film deposited by pulsed laser deposition (Mohanty et al., 2012 [10]). - Highlights: • TiO{sub 2} films were deposited by e-beam evaporation technique and post annealed under O{sub 2}/Ar at 500 °C. • The pristine film shows SPM behavior where as O{sub 2} and Ar annealed films demonstrate RTFM. • The presence of magnetic impurities has been discarded by various characterization techniques. • The magnetic moment is found to be higher in O{sub 2} annealed film than the Ar annealed one. • The higher M{sub s} in O{sub 2

  3. Tissue gas and blood analyses of human subjects breathing 80% argon and 20% oxygen

    Science.gov (United States)

    Horrigan, D. J.; Wells, C. H.; Guest, M. M.; Hart, G. B.; Goodpasture, J. E.

    1979-01-01

    Eight human volunteers, individually studied in a hyperbaric chamber, breathed: (1) air at 1 ATA; (2) 80% argon and 20% oxygen at 1 ATA for 30 min; (3) air at 1 ATA for 30 min; (4) 100% O2 at 1 ATA for 30 min; (5) air at 1 ATA for 30 min; (6) 100% O2 at 2 ATA for 60 min; and (7) 80% argon and 20% oxygen at 1 ATA for 30 min. Oxygen, carbon dioxide, nitrogen, and argon tensions were measured in muscle and subcutaneous tissue by mass spectroscopic analyses. Venous blood obtained at regular intervals was analyzed for coagulation and fibrinolytic factors. Inert gas narcosis was not observed. After breathing argon for 30 min, muscle argon tensions were almost three times the subcutaneous tensions. Argon wash-in mirrored nitrogen wash-out. Argon wash-in and wash-out had no effect on tissue PO2 or PCO2. Coagulation and fibrinolytic changes usually associated with vascular bubbles were absent.

  4. Tissue gas and blood analyses of human subjects breathing 80% argon and 20% oxygen

    Science.gov (United States)

    Horrigan, D. J.; Wells, C. H.; Guest, M. M.; Hart, G. B.; Goodpasture, J. E.

    1979-01-01

    Eight human volunteers, individually studied in a hyperbaric chamber, breathed: (1) air at 1 ATA; (2) 80% argon and 20% oxygen at 1 ATA for 30 min; (3) air at 1 ATA for 30 min; (4) 100% O2 at 1 ATA for 30 min; (5) air at 1 ATA for 30 min; (6) 100% O2 at 2 ATA for 60 min; and (7) 80% argon and 20% oxygen at 1 ATA for 30 min. Oxygen, carbon dioxide, nitrogen, and argon tensions were measured in muscle and subcutaneous tissue by mass spectroscopic analyses. Venous blood obtained at regular intervals was analyzed for coagulation and fibrinolytic factors. Inert gas narcosis was not observed. After breathing argon for 30 min, muscle argon tensions were almost three times the subcutaneous tensions. Argon wash-in mirrored nitrogen wash-out. Argon wash-in and wash-out had no effect on tissue PO2 or PCO2. Coagulation and fibrinolytic changes usually associated with vascular bubbles were absent.

  5. Thermophysical properties of argon

    Energy Technology Data Exchange (ETDEWEB)

    Jaques, A.

    1988-02-01

    The entire report consists of tables of thermodynamic properties (including sound velocity, thermal conductivity and diffusivity, Prandtl number, density) of argon at 86 to 400/degree/K, in the form of isobars over 0.9 to 100 bars. (DLC)

  6. 氩气刀配合分叉型被膜金属支架置入治疗气管隆突处狭窄16例%Argon plasma coagulation combined with bifurcated metal stents for treatment of airway stenosis in the carinal region A 16-case analysis

    Institute of Scientific and Technical Information of China (English)

    王洪武; 周云芝; 马洪明; 罗凌飞; 李晶; 邹珩; 李冬妹

    2009-01-01

    纳入16例气管隆突处气道狭窄患者,其中良性病变4例,恶件病变12例.对气道内病变先用氩等离子体凝固清除,随后放置气道分叉型金属支架.所选支架均为国产Z型不锈钢被膜支架.L型及I型支架均在软质气管镜引导下放置,Y型支架在气管镜和透视结合下放置.氩等离子体凝固治疗前气管、左、右主支气管的阻塞程度分别为(58.8±9.1)%,(67.4±7.4)%及(69.6±8.9)%,氩等离子体凝固首次消融后的阻塞程度分别为(7.5±2.4)%,(19.4±4.1)%及(27.6±5.4)%.所有患者胸闷、气憋症状均有明显改善,气促指数降低,体能状况Kamofsky评分增高.12例患者一次成功放置支架,其中9例为Y型:4例放置失败,其中2例肺癌患者隆突较宽,Y型支架难以置入,改用L型+I型.患者中位生存时间为10个月,平均生存时间为13个月.结果提示,氩等离子体凝固结合分叉型被膜金属支架置入治疗气管隆突处狭窄可以改善患者梗阻症状,提高生活质量.%A total of 16 patients with airway stenosis including benign lesion (n=4) and malignant disease (n=12) were treated with argon plasma coagulation (APC) and Z-type covered retrievable metallic stent.L-and I-type stents were placed by guidance of brenchoscope,while Y-type stent was placed by the guidance of both bronchoscope and fluoroscope.Airway stenosis was from (58.8 +9.1)% before APC to (7.5±2.4)% after APC in tracheal,from (67.4±7.4)% to (19.4±4.1)% in left main bronchus,from (69.6±8.9)% to (27.6±5.4)% in right main bronchus.Symptoms of chest distress and breathlessness were improved remarkably,tachypnea indexes were decreased,but Kamofsky performance scope were increased.Twelve stents were successfully installed by the first time,including 9 Y-shape;otherwise,4 stents failed to be installed because the carinal was too wide to insert the Y-shape stent in two patients with lung cancer,finally,L+I type stents were used.Median survival time after successful

  7. Argon plasma coagulation and hyperbaric oxygen therapy in chronic radiation proctopathy, effectiveness and impact on tissue toxicity Argón plasma y oxígeno hiperbárico para el control de la rectorragia crónica secundaria a la proctopatía por radiación

    Directory of Open Access Journals (Sweden)

    Julio César Álvaro-Villegas

    2011-11-01

    Full Text Available Background: chronic radiation proctopathy (CRP is associated with recurrent rectal bleeding and transfusional requirements. Argon plasma coagulation (APC and hyperbaric oxygen therapy (HOT have been shown to be effective in the control of CRP. No prospective comparisons have been reported between these treatments. Aim: the aim was to evaluate the effectiveness, safety and impact on tissue toxicity of APC compared to HOT in patients with CRP. Material and methods: a prospective study for evaluating treatment response was conducted. Patients with cervical cancer and CRP with rectal bleeding were recruited. They had not received previous treatment. Collected data included: demographics, previous radiation dosage, duration and severity of rectal bleeding. Hemoglobin, transfusional requirements, and tissue toxicity (SOMA LENT questionnaire at baseline and at 1, 2, and 3 months follow up were recorded. Results: thirty-one patients were included, 14 in the APC group and 17 in the HOT group. No response was noted in 13 and 18% of patients in the APC and HOT group respectively (p = NS. At the 1 and 2 months follow-up, the APC group showed a significantly better response in terms of transfusional requirements (0.6 vs. 3.4 and 0.7 vs. 2.5 and tissue toxicity score (5.3 vs. 8.6 and 3.8 vs. 7.248. After 3 months, both groups showed further improvement in all parameters without significant differences between them. Conclusions: APC and HOT were effective, safe and decreased the tissue toxicity scores in patients with CRP. However, response rate was higher and faster in the APC group.Introducción: la proctopatía por radiación (PPR se asocia con rectorragía recurrente y requerimientos de trasfusiones. La coagulación con argón plasma (APC y la terapia con oxígeno hiperbárico (HOT han sido efectivas en el control de la PPR. No hay estudios prospectivos comparativos entre ambas técnicas. Objetivo: el objetivo del estudio es evaluar la efectividad

  8. Future liquid Argon detectors

    CERN Document Server

    Rubbia, A

    2013-01-01

    The Liquid Argon Time Projection Chamber offers an innovative technology for a new class of massive detectors for rare-event detection. It is a precise tracking device that allows three-dimensional spatial reconstruction with mm-scale precision of the morphology of ionizing tracks with the imaging quality of a "bubble chamber", provides $dE/dx$ information with high sampling rate, and acts as high-resolution calorimeter for contained events. First proposed in 1977 and after a long maturing process, its holds today the potentialities of opening new physics opportunities by providing excellent tracking and calorimetry performance at the relevant multi-kton mass scales, outperforming other techniques. In this paper, we review future liquid argon detectors presently being discussed by the neutrino physics community.

  9. Developing Detectors for Scintillation Light in Liquid Argon for DUNE

    Energy Technology Data Exchange (ETDEWEB)

    Howard, Bruce [Fermilab

    2016-12-22

    The Deep Underground Neutrino experiment will conduct a broad program of physics research by studying a beam of neutrinos from Fermilab, atmospheric neutrinos, neutrinos from potential supernovae, and potential nucleon decay events. In pursuit of these studies, the experiment will deploy four 10kt fiducial mass liquid argon time projection chambers underground in Lead, South Dakota. Liquid argon time projection chambers allow high-resolution tracking and energy measurements. A precise timing signal is needed to provide the necessary time stamp to localize events in the drift direction. As liquid argon is a natural scintillator, a photon detection system will be deployed to provide such a signal, especially for non-beam events. In the baseline design for the single-phase time projection chamber, the detectors are contained within the anode plane assemblies. The design of two prototypes utilizing wavelength shifters and light guides are presented, and aspects of the research and development program are discussed.

  10. Application of argon beam coagulator in high abdominal pressure management during laparoscopic hepatectomy%氩气凝血器在腹腔镜肝脏切除中高气腹压的处理

    Institute of Scientific and Technical Information of China (English)

    唐劲草; 刘荣

    2009-01-01

    目的:探讨氩气凝血器在腹腔镜肝脏切除应用中腹压过高的解决方法.方法:总结我院2008年8-12月以来行腹腔镜下肝脏切除手术中应用氩气凝血器处理肝脏断面的病例7例,分别在氩气凝血器处理肝脏断面时关闭和打开Trocar排气阀,并测试2min后腹压值,进行统计学分析.结果:LH术中在应用氩气凝血器同时打开Trocar排气阀,使用前腹压值(11.571±0.787)mmHg(1mmHg=0.133kPa),与使用后腹压值(12.143±0.900)mmHg比较无统计学差异;而当关闭Trocar排气阀,则可以发现腹压值明显升高,使用前腹压值(12.429±0.976)mmHg与使用后腹压值(21.571±1.718)mmHg比较有明显统计学差异(P<0.05).结论:在使用氩气刀的同时打开Trocar排气阀,可有效解决腹压过高的问题.

  11. Electrical and spectroscopic characterization of a surgical argon plasma discharge

    Science.gov (United States)

    Keller, Sandra; Bibinov, Nikita; Neugebauer, Alexander; Awakowicz, Peter

    2013-01-01

    For electrosurgical procedures, the argon plasma coagulation (APC) discharge is a well-established atmospheric-pressure plasma tool for thermal haemostasis and devitalization of biological tissue. To characterize this plasma source, voltage-current measurements, microphotography, optical emission spectroscopy and numerical simulation are applied. Two discharge modes are established during the operation of the APC plasma source. A short transient spark discharge is ignited within the positive half period of the applied high voltage after a streamer channel connects the APC probe and the counter-electrode. During the second phase, which continues under negative high voltage, a glow discharge is stabilized in the plasma channel.

  12. Microrheological Coagulation Assay Exploiting Micromechanical Resonators.

    Science.gov (United States)

    Padovani, Francesco; Duffy, James; Hegner, Martin

    2017-01-03

    Rheological measurements in biological liquids yield insights into homeostasis and provide information on important molecular processes that affect fluidity. We present a fully automated cantilever-based method for highly precise and sensitive measurements of microliter sample volumes of human blood plasma coagulation (0.009 cP for viscosity range 0.5-3 cP and 0.0012 g/cm(3) for density range 0.9-1.1 g/cm(3)). Microcantilever arrays are driven by a piezoelectric element, and resonance frequencies and quality factors of sensors that change over time are evaluated. A highly accurate approximation of the hydrodynamic function is introduced that correlates resonance frequency and quality factor of cantilever beams immersed in a fluid to the viscosity and density of that fluid. The theoretical model was validated using glycerol reference solutions. We present a surface functionalization protocol that allows minimization of unspecific protein adsorption onto cantilevers. Adsorption leads to measurement distortions and incorrect estimation of the fluid parameters (viscosity and density). Two hydrophilic terminated self-assembled monolayers (SAMs) sensor surfaces are compared to a hydrophobic terminated SAM coating. As expected, the hydrophobic modified surfaces induced the highest mass adsorption and could promote conformational changes of the proteins and subsequent abnormal biological activity. Finally, the activated partial thromboplastin time (aPTT) coagulation assay was performed, and the viscosity, density, and coagulation rate of human blood plasma were measured along with the standard coagulation time. The method could extend and improve current coagulation testing.

  13. Cancer and blood coagulation.

    Science.gov (United States)

    Boccaccio, C; Medico, E

    2006-05-01

    In human patients, blood coagulation disorders often associate with cancer, even in its early stages. Recently, in vitro and in vivo experimental models have shown that oncogene expression, or inactivation of tumour suppressor genes, upregulate genes that control blood coagulation. These studies suggest that activation of blood clotting, leading to peritumoral fibrin deposition, is instrumental in cancer development. Fibrin can indeed build up a provisional matrix, supporting the invasive growth of neoplastic tissues and blood vessels. Interference with blood coagulation can thus be considered as part of a multifaceted therapeutic approach to cancer.

  14. Dust coagulation in ISM

    Science.gov (United States)

    Chokshi, Arati; Tielens, Alexander G. G. M.; Hollenbach, David

    1989-01-01

    Coagulation is an important mechanism in the growth of interstellar and interplanetary dust particles. The microphysics of the coagulation process was theoretically analyzed as a function of the physical properties of the coagulating grains, i.e., their size, relative velocities, temperature, elastic properties, and the van der Waal interaction. Numerical calculations of collisions between linear chains provide the wave energy in individual particles and the spectrum of the mechanical vibrations set up in colliding particles. Sticking probabilities are then calculated using simple estimates for elastic deformation energies and for the attenuation of the wave energy due to absorption and scattering processes.

  15. Filamentation of ultrashort laser pulses of different wavelengths in argon

    Indian Academy of Sciences (India)

    XIEXING QI; WENBIN LIN

    2017-02-01

    We investigate the filaments formed by the ultrashort laser pulses with different wavelengths of 400 nm, 586 nm and 800 nm propagating in argon. Numerical results show that, when the input power or the ratio of the input power to the critical power is given, the pulse with 400 nm wavelength has the largest on-axis intensity, as well as the narrowest filament and the most stable beam radius. These results indicate that the pulse with shorter wavelength is more suitable for the long-range propagation in argon.

  16. Disseminated intravascular coagulation (DIC)

    Science.gov (United States)

    ... Jr, Silberstein LE, et al, eds. Hematology: Basic Principles and Practice . 6th ed. Philadelphia, PA: Elsevier Saunders; 2013:chap 141. Thachil J, Toh CH. Current concepts in the management of disseminated intravascular coagulation. Thromb Res . 2012;129 ...

  17. Coagulation and Mental Disorders

    Directory of Open Access Journals (Sweden)

    Silvia Hoirisch-Clapauch

    2014-10-01

    Full Text Available The neurovascular unit is a key player in brain development, homeostasis, and pathology. Mental stress affects coagulation, while severe mental illnesses, such as recurrent depression and schizophrenia, are associated with an increased thrombotic risk and cardiovascular morbidity. Evidence indicates that the hemostatic system is involved to some extent in the pathogenesis, morbidity, and prognosis of a wide variety of psychiatric disorders. The current review focuses on emerging data linking coagulation and some psychiatric disorders.

  18. Depleted argon from underground sources

    Energy Technology Data Exchange (ETDEWEB)

    Back, H.O.; /Princeton U.; Alton, A.; /Augustana U. Coll.; Calaprice, F.; Galbiati, C.; Goretti, A.; /Princeton U.; Kendziora, C.; /Fermilab; Loer, B.; /Princeton U.; Montanari, D.; /Fermilab; Mosteiro, P.; /Princeton U.; Pordes, S.; /Fermilab

    2011-09-01

    Argon is a powerful scintillator and an excellent medium for detection of ionization. Its high discrimination power against minimum ionization tracks, in favor of selection of nuclear recoils, makes it an attractive medium for direct detection of WIMP dark matter. However, cosmogenic {sup 39}Ar contamination in atmospheric argon limits the size of liquid argon dark matter detectors due to pile-up. The cosmic ray shielding by the earth means that Argon from deep underground is depleted in {sup 39}Ar. In Cortez Colorado a CO{sub 2} well has been discovered to contain approximately 500ppm of argon as a contamination in the CO{sub 2}. In order to produce argon for dark matter detectors we first concentrate the argon locally to 3-5% in an Ar, N{sub 2}, and He mixture, from the CO{sub 2} through chromatographic gas separation. The N{sub 2} and He will be removed by continuous cryogenic distillation in the Cryogenic Distillation Column recently built at Fermilab. In this talk we will discuss the entire extraction and purification process; with emphasis on the recent commissioning and initial performance of the cryogenic distillation column purification.

  19. The Liquid Argon Purity Demonstrator

    CERN Document Server

    Adamowski, M; Dvorak, E; Hahn, A; Jaskierny, W; Johnson, C; Jostlein, H; Kendziora, C; Lockwitz, S; Pahlka, B; Plunkett, R; Pordes, S; Rebel, B; Schmitt, R; Stancari, M; Tope, T; Voirin, E; Yang, T

    2014-01-01

    The Liquid Argon Purity Demonstrator was an R&D test stand designed to determine if electron drift lifetimes adequate for large neutrino detectors could be achieved without first evacuating the cryostat. We describe here the cryogenic system, its operations, and the apparatus used to determine the contaminant levels in the argon and to measure the electron drift lifetime. The liquid purity obtained by this system was facilitated by a gaseous argon purge. Additionally, gaseous impurities from the ullage were prevented from entering the liquid at the gas-liquid interface by condensing the gas and filtering the resulting liquid before returning to the cryostat. The measured electron drift lifetime in this test was greater than 6 ms, sustained over several periods of many weeks. Measurements of the temperature profile in the argon, to assess convective flow and boiling, were also made and are compared to simulation.

  20. The Liquid Argon Purity Demonstrator

    Energy Technology Data Exchange (ETDEWEB)

    Adamowski, M.; Carls, B.; Dvorak, E.; Hahn, A.; Jaskierny, W.; Johnson, C.; Jostlein, H.; Kendziora, C.; Lockwitz, S.; Pahlka, B.; Plunkett, R.; Pordes, S.; Rebel, B.; Schmitt, R.; Stancari, M.; Tope, T.; Voirin, E.; Yang, T.

    2014-07-01

    The Liquid Argon Purity Demonstrator was an R&D test stand designed to determine if electron drift lifetimes adequate for large neutrino detectors could be achieved without first evacuating the cryostat. We describe here the cryogenic system, its operations, and the apparatus used to determine the contaminant levels in the argon and to measure the electron drift lifetime. The liquid purity obtained by this system was facilitated by a gaseous argon purge. Additionally, gaseous impurities from the ullage were prevented from entering the liquid at the gas-liquid interface by condensing the gas and filtering the resulting liquid before returning to the cryostat. The measured electron drift lifetime in this test was greater than 6 ms, sustained over several periods of many weeks. Measurements of the temperature profile in the argon, to assess convective flow and boiling, were also made and are compared to simulation.

  1. Liquid argon calorimeter performance at high rates

    CERN Document Server

    Seifert, F; The ATLAS collaboration

    2012-01-01

    The expected increase of luminosity at HL-LHC by a factor of ten with respect to LHC luminosities has serious consequences for the signal reconstruction, radiation hardness requirements and operations of the ATLAS liquid argon calorimeters in the endcap, respectively forward region. Small modules of each type of calorimeter have been built and exposed to a high intensity proton beam of 50 GeV at IHEP/Protvino. The beam is extracted via the bent crystal technique, offering the unique opportunity to cover intensities ranging from $10^6$ p/s up to $10^{12}$ p/s. This exceeds the deposited energy per time expected at HL-LHC by more than a factor of 100. The correlation between beam intensity and the read-out signal has been studied. The data show clear indications of pulse shape distortion due to the high ionization build-up, in agreement with MC expectations. This is also confirmed from the dependence of the HV currents on beam intensity.

  2. Liquid Argon Calorimeter performance at High Rates

    CERN Document Server

    Seifert, F; The ATLAS collaboration

    2013-01-01

    The expected increase of luminosity at HL-LHC by a factor of ten with respect to LHC luminosities has serious consequences for the signal reconstruction, radiation hardness requirements and operations of the ATLAS liquid argon calorimeters in the endcap, respectively forward region. Small modules of each type of calorimeter have been built and exposed to a high intensity proton beam of 50 GeV at IHEP/Protvino. The beam is extracted via the bent crystal technique, offering the unique opportunity to cover intensities ranging from $10^6$ p/s up to $3\\cdot10^{11}$ p/s. This exceeds the deposited energy per time expected at HL-LHC by more than a factor of 100. The correlation between beam intensity and the read-out signal has been studied. The data show clear indications of pulse shape distortion due to the high ionization build-up, in agreement with MC expectations. This is also confirmed from the dependence of the HV currents on beam intensity.

  3. [Blood coagulation in hyperthermia].

    Science.gov (United States)

    Zwierzina, W D; Herold, M; Günther, R; Kunz, F

    1980-01-01

    Young healthy volunteers were treated with physical hyperthermia (baths) in order to investigate changes in blood coagulation. Such therapy is used in the treatment of rheumatic diseases. Single hot baths (mean body temperature 38,2-39,9 degrees C) resulted in a rise of fibrinogen, factors IX and XII, maximal amplitude of the thrombelastogram and hemoglobin and in a decrease of plasminogen. In a series of hypothermic baths no additional changes of coagulation or fibrinolysis could be found. The results suggest that hyperthermia causes a tendency to thrombosis.

  4. A pressurized argon gas TPC as DUNE near detector

    CERN Document Server

    Martin-Albo, J

    2016-01-01

    DUNE is a new international experiment for neutrino physics and nucleon decay searches. It will consist of two detectors, about 1300 km apart, exposed to a multi-megawatt neutrino beam that will be built at Fermilab. One of the two detectors will be installed several hundred meters downstream of the neutrino production point with the primary role of characterising the energy spectrum and composition of the beam as well as performing precision measurements of neutrino cross sections. For the design of this so-called near detector, the DUNE Collaboration is considering, among other technologies, a pressurized argon gas time projection chamber. Such a detector, thanks to its low density and low detection thresholds, would allow the detailed measurement in argon of nuclear effects at the neutrino interaction vertex, which are considered at present one of the most important sources of systematic uncertainty for neutrino oscillation measurements.

  5. Readiness of the ATLAS Liquid Argon Calorimeter for LHC Collisions

    CERN Document Server

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Zitoun, R; Zivkovic, L; Zmouchko, V V; Zobernig, G; Zoccoli, A; zur Nedden, M; Zutshi, V

    2010-01-01

    The ATLAS liquid argon calorimeter has been operating continuously since August 2006. At this time, only part of the calorimeter was readout, but since the beginning of 2008, all calorimeter cells have been connected to the ATLAS readout system in preparation for LHC collisions. This paper gives an overview of the liquid argon calorimeter performance measured in situ with random triggers, calibration data, cosmic muons, and LHC beam splash events. Results on the detector operation, timing performance, electronics noise, and gain stability are presented. High energy deposits from radiative cosmic muons and beam splash events allow to check the intrinsic constant term of the energy resolution. The uniformity of the electromagnetic barrel calorimeter response along eta (averaged over phi) is measured at the percent level using minimum ionizing cosmic muons. Finally, studies of electromagnetic showers from radiative muons have been used to cross-check the Monte Carlo simulation. The performance results obtained u...

  6. Electron Impact Induced VUV Emission from Argon

    Science.gov (United States)

    Young, J. A.; Malone, C. P.; Johnson, P. V.

    2011-10-01

    Emission intensity and spectra are important tools for diagnosing plasma properties such as electron temperature and neutral density. In order to properly interpret emissions from low-density plasmas, accurate cross sections are needed, particularly low energy electron-impact cross sections. Of interest are the cross sections for Argon, a common species used in industrial and lighting applications. In this paper, we present recent measurements of electron-impact induced VUV emissions from Ar using a magnetically collimated monoenergetic beam of electrons and a 0.2m spectrometer. Specifically, we present emission excitation functions for both Ar I(1048 Å) and Ar I(1066 Å) emissions. Similarities and differences between current results and previously published emission results will be discussed. Also discussed will be the relation to recent electron energy loss results.

  7. Cryogenic System for the Test Facilities of the ATLAS Liquid Argon Calorimeter Modules

    CERN Document Server

    Bremer, J; Chalifour, M; Haug, F; Passardi, Giorgio; Tischhauser, Johann

    1998-01-01

    To perform cold tests on the different modules of the ATLAS liquid argon calorimeter, a cryogenic system has been constructed and is now operated at the CERN North Experimental Area. Three different test cryostats will house the modules, which can also be exposed to particle beams for calibration purposes. The three cryostats share a common liquid argon and liquid nitrogen distribution system. The system is rather complex since it has to allow operations of the three cryostats at the same time. Liquid nitrogen is used as cold source for both the cool-down of the cryostats and for normal operation of the cryostats filled with liquid argon.

  8. Overview of the coagulation system

    Directory of Open Access Journals (Sweden)

    Sanjeev Palta

    2014-01-01

    Full Text Available Coagulation is a dynamic process and the understanding of the blood coagulation system has evolved over the recent years in anaesthetic practice. Although the traditional classification of the coagulation system into extrinsic and intrinsic pathway is still valid, the newer insights into coagulation provide more authentic description of the same. Normal coagulation pathway represents a balance between the pro coagulant pathway that is responsible for clot formation and the mechanisms that inhibit the same beyond the injury site. Imbalance of the coagulation system may occur in the perioperative period or during critical illness, which may be secondary to numerous factors leading to a tendency of either thrombosis or bleeding. A systematic search of literature on PubMed with MeSH terms ′coagulation system, haemostasis and anaesthesia revealed twenty eight related clinical trials and review articles in last 10 years. Since the balance of the coagulation system may tilt towards bleeding and thrombosis in many situations, it is mandatory for the clinicians to understand physiologic basis of haemostasis in order to diagnose and manage the abnormalities of the coagulation process and to interpret the diagnostic tests done for the same.

  9. Attachment cooling of electrons in oxygen-argon and SF6-argon mixtures

    Science.gov (United States)

    Babaeva, Natalia; Kim, Sung Jin; Park, Gan Young; Lee, Jae Koo

    2004-09-01

    In e-beam sustained plasma different electron temperature can be obtained. Thus, in plasma of capacitive RF discharges in inert gases typical electron temperature is of the order of 2-3 eV. At certain conditions, in plasma of electronegative gases electron temperature can approach ion/neutral temperature. We consider e-beam sustained plasma of electronegative gases and their mixtures with argon where the main mechanism of plasma neutralization is connected with electron-molecule attachment. In such plasma, due to retardation of fast electrons of e-beam secondary electrons are created which loose their energy due to attachment. It is shown, that at certain conditions (in dependence of the e-beam intensity and spectrum of secondary electrons) electron temperature can obtain the values comparable or even less than temperature of neutral component. The effect can be explained by the increase of attachment rate coefficient with the increase of electron temperature (mean electron energy). Such a dependence leads to attachment of the fastest plasma electrons and selective loss of electrons whose energy exceeds the mean electron energy and, as a result, to effective electron cooling. The theoretical and numerical analysis of the problem has been conducted. The numerical results obtained using ELENDIF code are compared with Particle-in-cell/Monte Carlo simulations under similar conditions.

  10. COAGULATION ACTIVITY IN LIVER DISEASE

    Directory of Open Access Journals (Sweden)

    Dr. Sheikh Sajjadieh Mohammad Reza

    2009-07-01

    Full Text Available Patients with advanced hepatic failure may present with the entire spectrum of coagulation factor deficiencies. This study was designed to determine laboratory abnormalities in coagulation in chronic liver disease and the association of these abnormalities with the extent of chronic hepatitis and cirrhosis. Coagulation markers were assayed in 60 participants: 20 patients with chronic hepatitis, 20 patients with cirrhosis, and 20 healthy individuals (control. Plasma levels of anti-thrombin III were determined by a chromogenic substrate method, and plasma concentrations of fibrinogen were analyzed by the Rutberg method. Commercially available assays were used for laboratory coagulation tests. The levels of coagualation activity markers in patients with chronic liver disease were significantly different in comparison to those in healthy participants. These results indicate the utility of measuring markers for coagulation activity in determining which cirrhosis patients are more susceptible to disseminated intravascular coagulation.

  11. Attainable superheat of argon-helium, argon-neon solutions.

    Science.gov (United States)

    Baidakov, Vladimir G; Kaverin, Aleksey M; Andbaeva, Valentina N

    2008-10-16

    The method of lifetime measurement has been used to investigate the kinetics of spontaneous boiling-up of superheated argon-helium and argon-neon solutions. Experiments were made at a pressure of p = 1.5 MPa and concentrations up to 0.33 mol% in the range of nucleation rates from 10 (4) to 10 (8) s (-1) m (-3). The homogeneous nucleation regime has been distinguished. With good agreement between experimental data and homogeneous nucleation theory in temperature and concentration dependences of the nucleation rate, a systematic underestimation by 0.25-0.34 K has been revealed in superheat temperatures over the saturated line attained by experiment as compared with theoretical values calculated in a macroscopic approximation. The revealed disagreement between theory and experiment is connected with the dependence of the properties of new-phase nuclei on their size.

  12. Readiness of the ATLAS liquid argon calorimeter for LHC collisions

    Science.gov (United States)

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O.; Osculati, B.; Osuna, C.; Otec, R.; P Ottersbach, J.; Ould-Saada, F.; Ouraou, A.; Ouyang, Q.; Owen, M.; Owen, S.; Ozcan, V. E.; Ozone, K.; Ozturk, N.; Pacheco Pages, A.; Padhi, S.; Padilla Aranda, C.; Paganis, E.; Pahl, C.; Paige, F.; Pajchel, K.; Pal, A.; Palestini, S.; Pallin, D.; Palma, A.; Palmer, J. D.; Pan, Y. B.; Panagiotopoulou, E.; Panes, B.; Panikashvili, N.; Panitkin, S.; Pantea, D.; Panuskova, M.; Paolone, V.; Papadopoulou, Th. D.; Park, S. J.; Park, W.; Parker, M. A.; Parker, S. I.; Parodi, F.; Parsons, J. A.; Parzefall, U.; Pasqualucci, E.; Passardi, G.; Passeri, A.; Pastore, F.; Pastore, Fr.; Pásztor, G.; Pataraia, S.; Pater, J. R.; Patricelli, S.; Patwa, A.; Pauly, T.; Peak, L. S.; Pecsy, M.; Pedraza Morales, M. I.; Peleganchuk, S. V.; Peng, H.; Penson, A.; Penwell, J.; Perantoni, M.; Perez, K.; Perez Codina, E.; Pérez García-Estañ, M. T.; Perez Reale, V.; Perini, L.; Pernegger, H.; Perrino, R.; Perrodo, P.; Persembe, S.; Perus, P.; Peshekhonov, V. D.; Petersen, B. 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P.; Schmieden, K.; Schmitt, C.; Schmitz, M.; Schott, M.; Schouten, D.; Schovancova, J.; Schram, M.; Schreiner, A.; Schroeder, C.; Schroer, N.; Schroers, M.; Schuler, G.; Schultes, J.; Schultz-Coulon, H.-C.; Schumacher, J.; Schumacher, M.; Schumm, B. A.; Schune, Ph.; Schwanenberger, C.; Schwartzman, A.; Schwemling, Ph.; Schwienhorst, R.; Schwierz, R.; Schwindling, J.; Scott, W. G.; Searcy, J.; Sedykh, E.; Segura, E.; Seidel, S. C.; Seiden, A.; Seifert, F.; Seixas, J. M.; Sekhniaidze, G.; Seliverstov, D. M.; Sellden, B.; Seman, M.; Semprini-Cesari, N.; Serfon, C.; Serin, L.; Seuster, R.; Severini, H.; Sevior, M. E.; Sfyrla, A.; Shamim, M.; Shan, L. Y.; Shank, J. T.; Shao, Q. T.; Shapiro, M.; Shatalov, P. B.; Shaver, L.; Shaw, C.; Shaw, K.; Sherman, D.; Sherwood, P.; Shibata, A.; Shimojima, M.; Shin, T.; Shmeleva, A.; Shochet, M. J.; Shupe, M. A.; Sicho, P.; Sidoti, A.; Siebel, A.; Siegert, F.; Siegrist, J.; Sijacki, Dj.; Silbert, O.; Silva, J.; Silver, Y.; Silverstein, D.; Silverstein, S. B.; Simak, V.; Simic, Lj.; Simion, S.; Simmons, B.; Simonyan, M.; Sinervo, P.; Sinev, N. B.; Sipica, V.; Siragusa, G.; Sisakyan, A. N.; Sivoklokov, S. Yu.; Sjoelin, J.; Sjursen, T. B.; Skubic, P.; Skvorodnev, N.; Slater, M.; Slavicek, T.; Sliwa, K.; Sloper, J.; Sluka, T.; Smakhtin, V.; Smirnov, S. Yu.; Smirnov, Y.; Smirnova, L. N.; Smirnova, O.; Smith, B. C.; Smith, D.; Smith, K. M.; Smizanska, M.; Smolek, K.; Snesarev, A. A.; Snow, S. W.; Snow, J.; Snuverink, J.; Snyder, S.; Soares, M.; Sobie, R.; Sodomka, J.; Soffer, A.; Solans, C. A.; Solar, M.; Solfaroli Camillocci, E.; Solodkov, A. A.; Solovyanov, O. V.; Soluk, R.; Sondericker, J.; Sopko, V.; Sopko, B.; Sosebee, M.; Sosnovtsev, V. V.; Sospedra Suay, L.; Soukharev, A.; Spagnolo, S.; Spanò, F.; Speckmayer, P.; Spencer, E.; Spighi, R.; Spigo, G.; Spila, F.; Spiwoks, R.; Spousta, M.; Spreitzer, T.; Spurlock, B.; Denis, R. D. St.; Stahl, T.; Stamen, R.; Stancu, S. N.; Stanecka, E.; Stanek, R. W.; Stanescu, C.; Stapnes, S.; Starchenko, E. A.; Stark, J.; Staroba, P.; Starovoitov, P.; Stastny, J.; Staude, A.; Stavina, P.; Stavropoulos, G.; Steinbach, P.; Steinberg, P.; Stekl, I.; Stelzer, B.; Stelzer, H. J.; Stelzer-Chilton, O.; Stenzel, H.; Stevenson, K.; Stewart, G.; Stockton, M. C.; Stoerig, K.; Stoicea, G.; Stonjek, S.; Strachota, P.; Stradling, A.; Straessner, A.; Strandberg, J.; Strandberg, S.; Strandlie, A.; Strauss, M.; Strizenec, P.; Ströhmer, R.; Strom, D. M.; Strong, J. A.; Stroynowski, R.; Strube, J.; Stugu, B.; Stumer, I.; Soh, D. A.; Su, D.; Suchkov, S. I.; Sugaya, Y.; Sugimoto, T.; Suhr, C.; Suk, M.; Sulin, V. V.; Sultansoy, S.; Sumida, T.; Sun, X.; Sundermann, J. 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G.; Undrus, A.; Unel, G.; Unno, Y.; Urbaniec, D.; Urkovsky, E.; Urquijo, P.; Urrejola, P.; Usai, G.; Uslenghi, M.; Vacavant, L.; Vacek, V.; Vachon, B.; Vahsen, S.; Valenta, J.; Valente, P.; Valentinetti, S.; Valkar, S.; Valladolid Gallego, E.; Vallecorsa, S.; Valls Ferrer, J. A.; van Berg, R.; van der Graaf, H.; van der Kraaij, E.; van der Poel, E.; van der Ster, D.; van Eldik, N.; van Gemmeren, P.; van Kesteren, Z.; van Vulpen, I.; Vandelli, W.; Vandoni, G.; Vaniachine, A.; Vankov, P.; Vannucci, F.; Varela Rodriguez, F.; Vari, R.; Varnes, E. W.; Varouchas, D.; Vartapetian, A.; Varvell, K. E.; Vasilyeva, L.; Vassilakopoulos, V. I.; Vazeille, F.; Vegni, G.; Veillet, J. J.; Vellidis, C.; Veloso, F.; Veness, R.; Veneziano, S.; Ventura, A.; Ventura, D.; Venturi, M.; Venturi, N.; Vercesi, V.; Verducci, M.; Verkerke, W.; Vermeulen, J. C.; Vetterli, M. C.; Vichou, I.; Vickey, T.; Viehhauser, G. H. A.; Villa, M.; Villani, E. G.; Villaplana Perez, M.; Villate, J.; Vilucchi, E.; Vincter, M. G.; Vinek, E.; Vinogradov, V. B.; Viret, S.; Virzi, J.; Vitale, A.; Vitells, O. V.; Vivarelli, I.; Vives Vaques, F.; Vlachos, S.; Vlasak, M.; Vlasov, N.; Vogt, H.; Vokac, P.; Volpi, M.; Volpini, G.; von der Schmitt, H.; von Loeben, J.; von Radziewski, H.; von Toerne, E.; Vorobel, V.; Vorobiev, A. P.; Vorwerk, V.; Vos, M.; Voss, R.; Voss, T. T.; Vossebeld, J. H.; Vranjes, N.; Vranjes Milosavljevic, M.; Vrba, V.; Vreeswijk, M.; Vu Anh, T.; Vudragovic, D.; Vuillermet, R.; Vukotic, I.; Wagner, P.; Wahlen, H.; Walbersloh, J.; Walder, J.; Walker, R.; Walkowiak, W.; Wall, R.; Wang, C.; Wang, H.; Wang, J.; Wang, J. C.; Wang, S. M.; Ward, C. P.; Warsinsky, M.; Wastie, R.; Watkins, P. M.; Watson, A. T.; Watson, M. F.; Watts, G.; Watts, S.; Waugh, A. T.; Waugh, B. M.; Webel, M.; Weber, J.; Weber, M. D.; Weber, M.; Weber, M. S.; Weber, P.; Weidberg, A. R.; Weingarten, J.; Weiser, C.; Wellenstein, H.; Wells, P. S.; Wen, M.; Wenaus, T.; Wendler, S.; Wengler, T.; Wenig, S.; Wermes, N.; Werner, M.; Werner, P.; Werth, M.; Werthenbach, U.; Wessels, M.; Whalen, K.; Wheeler-Ellis, S. J.; Whitaker, S. P.; White, A.; White, M. J.; White, S.; Whiteson, D.; Whittington, D.; Wicek, F.; Wicke, D.; Wickens, F. J.; Wiedenmann, W.; Wielers, M.; Wienemann, P.; Wiglesworth, C.; Wiik, L. A. M.; Wildauer, A.; Wildt, M. A.; Wilhelm, I.; Wilkens, H. G.; Williams, E.; Williams, H. H.; Willis, W.; Willocq, S.; Wilson, J. A.; Wilson, M. G.; Wilson, A.; Wingerter-Seez, I.; Winklmeier, F.; Wittgen, M.; Wolter, M. W.; Wolters, H.; Wosiek, B. K.; Wotschack, J.; Woudstra, M. J.; Wraight, K.; Wright, C.; Wright, D.; Wrona, B.; Wu, S. L.; Wu, X.; Wulf, E.; Xella, S.; Xie, S.; Xie, Y.; Xu, D.; Xu, N.; Yamada, M.; Yamamoto, A.; Yamamoto, S.; Yamamura, T.; Yamanaka, K.; Yamaoka, J.; Yamazaki, T.; Yamazaki, Y.; Yan, Z.; Yang, H.; Yang, U. K.; Yang, Y.; Yang, Z.; Yao, W.-M.; Yao, Y.; Yasu, Y.; Ye, J.; Ye, S.; Yilmaz, M.; Yoosoofmiya, R.; Yorita, K.; Yoshida, R.; Young, C.; Youssef, S. P.; Yu, D.; Yu, J.; Yu, M.; Yu, X.; Yuan, J.; Yuan, L.; Yurkewicz, A.; Zaidan, R.; Zaitsev, A. M.; Zajacova, Z.; Zambrano, V.; Zanello, L.; Zarzhitsky, P.; Zaytsev, A.; Zeitnitz, C.; Zeller, M.; Zema, P. F.; Zemla, A.; Zendler, C.; Zenin, O.; Zenis, T.; Zenonos, Z.; Zenz, S.; Zerwas, D.; Zevi Della Porta, G.; Zhan, Z.; Zhang, H.; Zhang, J.; Zhang, Q.; Zhang, X.; Zhao, L.; Zhao, T.; Zhao, Z.; Zhemchugov, A.; Zheng, S.; Zhong, J.; Zhou, B.; Zhou, N.; Zhou, Y.; Zhu, C. G.; Zhu, H.; Zhu, Y.; Zhuang, X.; Zhuravlov, V.; Zilka, B.; Zimmermann, R.; Zimmermann, S.; Zimmermann, S.; Ziolkowski, M.; Zitoun, R.; Živković, L.; Zmouchko, V. V.; Zobernig, G.; Zoccoli, A.; Zur Nedden, M.; Zutshi, V.

    2010-12-01

    The ATLAS liquid argon calorimeter has been operating continuously since August 2006. At this time, only part of the calorimeter was readout, but since the beginning of 2008, all calorimeter cells have been connected to the ATLAS readout system in preparation for LHC collisions. This paper gives an overview of the liquid argon calorimeter performance measured in situ with random triggers, calibration data, cosmic muons, and LHC beam splash events. Results on the detector operation, timing performance, electronics noise, and gain stability are presented. High energy deposits from radiative cosmic muons and beam splash events allow to check the intrinsic constant term of the energy resolution. The uniformity of the electromagnetic barrel calorimeter response along η (averaged over φ) is measured at the percent level using minimum ionizing cosmic muons. Finally, studies of electromagnetic showers from radiative muons have been used to cross-check the Monte Carlo simulation. The performance results obtained using the ATLAS readout, data acquisition, and reconstruction software indicate that the liquid argon calorimeter is well-prepared for collisions at the dawn of the LHC era.

  13. Metal oxide morphology in argon-assisted glancing angle deposition

    Energy Technology Data Exchange (ETDEWEB)

    Sorge, J. B.; Taschuk, M. T.; Wakefield, N. G.; Sit, J. C.; Brett, M. J. [Department of Electrical and Computer Engineering, University of Alberta, Edmonton, AB T6G 2V4 (Canada); Department of Electrical and Computer Engineering, University of Alberta, Edmonton, AB T6G 2V4 (Canada) and NRC National Institute for Nanotechnology, Edmonton, AB T6G 2M9 (Canada)

    2012-03-15

    Glancing angle deposition (GLAD) is a thin film deposition technique capable of fabricating columnar architectures such as posts, helices, and chevrons with control over nanoscale film features. Argon bombardment during deposition modifies the GLAD process, producing films with new morphologies which have shown promise for sensing and photonic devices. The authors report modification of column tilt angle, film density, and specific surface area for 12 different metal oxide and fluoride film materials deposited using Ar-assisted GLAD. For the vapor flux/ion beam geometry and materials studied here, with increasing argon flux, the column tilt increases, film density increases, and specific surface area decreases. With a better understanding of the nature of property modification and the mechanisms responsible, the Ar-assisted deposition process can be more effectively targeted towards specific applications, including birefringent thin films or photonic crystal square spirals.

  14. Disseminated intravascular coagulation in cancer patients

    NARCIS (Netherlands)

    M. Levi

    2009-01-01

    Disseminated intravascular coagulation (DIC) is a syndrome that may complicate a variety of diseases, including malignant disease. DIC is characterized by widespread, intravascular activation of coagulation (leading to intravascular fibrin deposition) and simultaneous consumption of coagulation fact

  15. How Is Disseminated Intravascular Coagulation Treated?

    Science.gov (United States)

    ... the NHLBI on Twitter. How Is Disseminated Intravascular Coagulation Treated? Treatment for disseminated intravascular coagulation (DIC) depends ... and treat the underlying cause. Acute Disseminated Intravascular Coagulation People who have acute DIC may have severe ...

  16. Liquid Argon Barrel Cryostat Arrived

    CERN Multimedia

    Pailler, P

    Last week the first of three cryostats for the ATLAS liquid argon calorimeter arrived at CERN. It had travelled for 46 days over several thousand kilometers from Japan to CERN. During three years it has been fabricated by Kawasaki Heavy Industries Ltd. at Harima, close to Kobe, under contract from Brookhaven National Laboratory (BNL) of the U.S.. This cryostat consists of two concentric cylinders made of aluminium: the outer vacuum vessel with a diameter of 5.5 m and a length of 7 m, and the inner cold vessel which will contain the electromagnetic barrel calorimeter immersed in liquid argon. The total weight will be 270 tons including the detectors and the liquid argon. The cryostat is now located in building 180 where it will be equipped with 64 feed-throughs which serve for the passage of 122,880 electrical lines which will carry the signals of the calorimeter. After integration of the calorimeter, the solenoidal magnet of ATLAS will be integrated in the vacuum vessel. A final cold test of the cryostat inc...

  17. Argon-krypton ion laser as light source for medical photocoagulation applications

    Science.gov (United States)

    Kamiński, Wojciech; Warda, Piotr; Kasprzak, Jan; Kesik, Jerzy

    2013-01-01

    Photocoagulators are one of the most popular laser devices in medicine. Due to different kind of interaction of particular wavelength range of laser light with live tissues, sources of laser radiation which can cover as much as possible of visible spectrum are still very wanted (see [1,2]). In last years it also can be observed the intensive developing works on new photocoagulation technique called "micropulse coagulation" [3,4]. The most critical feature of lasers for micropulse coagulation is the possibility of fast switching between two selected laser power values. It seems that the good proposal for these applications can be ion laser filled with argon-krypton mixture. Authors previously have indicated the possibility of improvement of generation conditions in this type of laser in presence of buffer gases [5,6] and with use developed by authors pulse supply regime [7,8]. These improvements allow to obtain output power values of most important argon and krypton laser lines in laser filled with mixture of both gases, similar to values available in laser filled with pure gases. Presented in this paper the following researches are concerned on verification of possibilities of use of the developed laser system in photocoagulation with possibility of use of the laser system in micropulse coagulation technique.

  18. Composing Experimental Environment of PRIDE Argon cell

    Energy Technology Data Exchange (ETDEWEB)

    Noh, Seonho; Jang, Yongkuk; Cho, Il Je [Korea Atomic Energy Research Institute, Daejeon (Korea, Republic of)

    2015-10-15

    In PRIDE depleted Uranium feed material and a depleted Uranium mixed with some surrogate material are used for performing engineering scale Pyroprocessing. PRIDE has to maintain inert atmosphere because of the characteristic of Electrolytic Reduction technology, Electro refining technology, Electrowinning technology. The impurity concentration of the Argon cell has to be under 50 ppm(Oxygen, moisture). Atmospheric pressure changes and temperature changes can affect the Argon cell's impurity concentration. In this paper, how to compose the Argon cell impurity concentration under 50 ppm to make the exact optimal experimental environment(Oxygen, moisture) will be introduced. Composing the exact optimal experimental environment by supplying Argon gas have been introduced in this paper. Continuously supplying Argon gas which is heavier than the Oxygen through the bottom of the Argon cell the oxygen eventually discharged through the high vent fan and lower the impurity concentration of Oxygen.

  19. Structural determination of argon trimer

    Directory of Open Access Journals (Sweden)

    Xiguo Xie

    2015-09-01

    Full Text Available Rare gas clusters are model systems to investigate structural properties at finite size. However, their structures are difficult to be determined with available experimental techniques because of the strong coupling between the vibration and the rotation. Here we experimentally investigated multiple ionization and fragmentation dynamics of argon trimer by ultrashort intense laser fields and reconstructed their structures with Coulomb explosion technique. The measured structure distribution was compared with our finite-temperature ab initio calculations and the discrepancy was discussed. The present study provides a guidance for the development of theoretical methods for exploring the geometric structure of rare gas clusters.

  20. Kinetic modeling of the Townsend breakdown in argon

    Science.gov (United States)

    Macheret, S. O.; Shneider, M. N.

    2013-10-01

    Kinetic modeling of the Townsend breakdown in argon was performed in the "forward-back" approximation. The kinetic model was found to adequately describe the left branch of the Paschen curve, and the important role of ionization by fast ions and atoms near the cathode, as well as the increase in secondary emission coefficient in strong electric fields described in the literature, was confirmed. The modeling also showed that the electron energy distribution function develops a beam of high-energy electrons and that the runaway effect, i.e., the monotonic increase of the mean electron energy with the distance from the cathode, occurs at the left branch of the Paschen curve.

  1. Tin LPP plasma control in the argon cusp source

    Science.gov (United States)

    McGeoch, Malcolm W.

    2016-03-01

    The argon cusp plasma has been introduced [1,2] for 500W class tin LPP exhaust control in view of its high power handling, predicted low tin back-scatter from a beam dump, and avoidance of hydrogen usage. The physics of tin ion control by a plasma is first discussed. Experimentally, cusp stability and exhaust disc geometry have previously been proved at full scale [2], the equivalent of 300W-500W usable EUV. Here we verify operation of the plasma barrier that maintains a high argon density next to the collector, for its protection, and a low density in the long path toward the intermediate focus, for efficiency. A pressure differential of 2Pa has been demonstrated in initial work. Other aspects of tin LPP plasma control by the cusp have now been demonstrated using tin ions from a low Hz 130mJ CO2 laser pulse onto a solid tin surface at the cusp center. Plasma is rejected at the design to match a specified exhaust power is discussed. In view of this work, argon cusp exhaust control appears to be very promising for 500W class tin LPP sources.

  2. 氩离子凝固术联合腹腔镜食管裂孔疝修补术加胃底折叠术治疗食管裂孔疝合并Barrett食管的疗效观察%Clinical study of argon plasma coagulation combined with laparoscopic hiatal hernia repair and fundoplication in the treatment of hiatal hernia with Barrett esophagus

    Institute of Scientific and Technical Information of China (English)

    张成; 克力木; 李义亮; 苏福增; 李慧灵; 王志; 李赞林; 艾克拜尔; 阿扎提

    2015-01-01

    Objective To investigate the clinical efficacy of argon plasma coagulation (APC) combined with laparoscopic hiatal hernia repair and fundoplication in the treatment of hiatal hernia associated with Barrett esophagus.Methods A total of 61 cases of hiatal hernias with Barrett esophagus from June 2010 to January 2014 in the Department of Minimal Invasive Surgery, Hernia and Abdominal wall Surgery, People's Hospital of Xinjiang Uyhur Autonomous Region were prospectively enrolled and were randomly allocated into two groups by computer system.Twenty-nine patients received esomeprazole 40 mg/d after APC treatment for 8 weeks (APC with medicine group).Thirty-two patients underwent laparoscopic hiatal hernia repair and Nissen fundoplication after APC treatment (APC with surgery group).All the patients were reviewed by gastroscope and pathologic examination at half a year and one year after operation respectively.Differences of disease improvement and recurrence between the two groups were evaluated.Results In APC with medicine group, the Barrett's esophagus was relieved after one or two times of APC treatment, however, gastroscope and pathology revealed recurrence of Barrett's esophagus in 7 cases at half a year, and cumulative 16 cases of recurrences were detected after one year follow-up (16/29, 55.2%).In APC with surgery group, only one patient had recurrent Barrett's esophagus at half a year, and a total of two at one year follow-up by gastroscope examination(2/32, 6.3%).Significantly low recurrence rate of Barrett's esophagus was observed in APC with surgery group compared to APC with medicine group(P<0.01).Furthermore, recurrent hiatal hernia was detected in only one case in APC with surgery group.No esophageal cancer was found in both groups during follow-up.Conclusion APC combined with laparoscopic hiatal hernia repair and fundoplication is an ideal method for patients with hiatal hernia and Barrett's esophagus.%目的 探讨氩离子凝固术(APC)联合腹

  3. Obstetrical disseminated intravascular coagulation score.

    Science.gov (United States)

    Kobayashi, Takao

    2014-06-01

    Obstetrical disseminated intravascular coagulation (DIC) is usually a very acute, serious complication of pregnancy. The obstetrical DIC score helps with making a prompt diagnosis and starting treatment early. This DIC score, in which higher scores are given for clinical parameters rather than for laboratory parameters, has three components: (i) the underlying diseases; (ii) the clinical symptoms; and (iii) the laboratory findings (coagulation tests). It is justifiably appropriate to initiate therapy for DIC when the obstetrical DIC score reaches 8 points or more before obtaining the results of coagulation tests. Improvement of blood coagulation tests and clinical symptoms are essential to the efficacy evaluation for treatment after a diagnosis of obstetrical DIC. Therefore, the efficacy evaluation criteria for obstetrical DIC are also defined to enable follow-up of the clinical efficacy of DIC therapy.

  4. Disorders of coagulation in pregnancy.

    Science.gov (United States)

    Katz, D; Beilin, Y

    2015-12-01

    The process of haemostasis is complex and is further complicated in the parturient because of the physiological changes of pregnancy. Understanding these changes and the impact that they have on the safety profile of the anaesthetic options for labour and delivery is crucial to any anaesthetist caring for the parturient. This article analyses current theories on coagulation and reviews the physiological changes to coagulation that occur during pregnancy and the best methods with which to evaluate coagulation. Finally, we examine some of the more common disorders of coagulation that occur during pregnancy, including von Willebrand disease, common factor deficiencies, platelet disorders, the parturient on anticoagulants, and the more rare acute fatty liver of pregnancy, with a focus on their implications for neuraxial anaesthesia.

  5. Quality Control and Assurance for Coagulation Tests

    Institute of Scientific and Technical Information of China (English)

    彭黎明

    2006-01-01

    @@ The coagulation laboratory aids the clinician in assessing not only the bleeding patient but also the thrombotic patient. The techniques of coagulation laboratory are used to evaluate not only the coagulation system but also the anti-coagulation system, fibrinolytic system,platelet and vascular endothelial function. Enzymes, inhibitors, plasma factors and co-factors, cellular release products, and cell receptors can be measured in coagulation laboratory.

  6. Argon purge gas cooled by chill box

    Science.gov (United States)

    Spiro, L. W.

    1966-01-01

    Cooling argon purge gas by routing it through a shop-fabricated chill box reduces charring of tungsten inert gas torch head components. The argon gas is in a cooled state as it enters the torch and prevents buildup of char caused by the high concentrations of heat in the weld area during welding operations.

  7. Pulse Compression by Filamentation in Argon with an Acoustic Optical Programmable Dispersive Filter for Predispersion Compensation

    Institute of Scientific and Technical Information of China (English)

    CHEN Xiao-Wei; JIANG Yong-Liang; LENG Yu-Xin; LIU Jun; GE Xiao-Chun; LI Ru-Xin; XU Zhi-Zhan

    2006-01-01

    @@ We have experimentally demonstrated pulses 0.4 mJ in duration smaller than 12 fs with an excellent spatial beam profile by self-guided propagation in argon. The original 52fs pulses from the chirped pulsed amplification laser system are first precompressed to 32 fs by inserting an acoustic optical programmable dispersive filter instrument into the laser system for spectrum reshaping and dispersion compensation, and the pulse spectrum is subsequently broadened by filamentation in an argon cell. By using chirped mirrors for post-dispersion compensation, the pulses are successfully compressed to smaller than 12fs.

  8. Enhancement of negative capacitance effect in (CoFeZr){sub x}(CaF{sub 2}){sub (100−x)} nanocomposite films deposited by ion beam sputtering in argon and oxygen atmosphere

    Energy Technology Data Exchange (ETDEWEB)

    Koltunowicz, T.N., E-mail: t.koltunowicz@pollub.pl [Lublin University of Technology, 20-618 Lublin (Poland); Zhukowski, P., E-mail: p.zhukowski@pollub.pl [Lublin University of Technology, 20-618 Lublin (Poland); Bondariev, V. [Lublin University of Technology, 20-618 Lublin (Poland); Saad, A. [Al Balqa Applied University, Physics Department, P.O. Box 4545, Amman 11953 (Jordan); Fedotova, J.A. [National Center for Particles and High Energy Physics of Belarusian State University, 220040 Minsk (Belarus); Fedotov, A.K. [Belarusian State University, 220030 Minsk (Belarus); Milosavljević, M. [VINČA Institute of Nuclear Sciences, Belgrade University, P.O. Box 522, 11001 Belgrade (Serbia); Kasiuk, J.V. [National Center for Particles and High Energy Physics of Belarusian State University, 220040 Minsk (Belarus)

    2014-12-05

    Highlights: • (FeCoZr){sub x}(CaF{sub 2}){sub (100−x)} nanomaterals deposited in oxygen-containing atmosphere (Ar + O{sub 2}). • FeCoZr “cores” covered with FeCo-oxide “shells” embedded into nonoxygen dielectric matrix. • On σ(T{sub p}) are two minima related to the crossing zero line values of Θ{sub 1} = 90° and of Θ{sub 2} = −90°. - Abstract: The paper presents frequency f and temperature T{sub p} dependences of phase shift angle Θ, admittance σ and capacitance C{sub p} for the as-deposited and annealed (CoFeZr){sub x}(CaF{sub 2}){sub (100−x)} nanocomposite films deposited by ion-beam sputtering of a compound target in a mixed argon–oxygen gas atmosphere in vacuum chamber. The studied films presented metallic FeCoZr “cores” covered with FeCo-based oxide “shells” embedded into oxygen-free dielectric matrix (fluorite). It was found for the metallic phase content within the range of 52.2 at.% ⩽ x ⩽ 84.3 at.% in low-f region that Θ values were negative, while in the high-f region we observed the Θ < 0{sup o}. It was obtained that the f-dependences of capacitance module displayed minimum at the corresponding frequency when the Θ(f) crossed its zero line Θ = 0{sup o}. It was also observed that the σ(T{sub p}) dependence displayed the occurrence of two minima that were related to the values of Θ{sub 1} = 90° (the first minimum) and of Θ{sub 2} = −90° (the second one). Some possible reasons of such behavior of (CoFeZr){sub x}(CaF{sub 2}){sub (100−x)} nanocomposite films are discussed.

  9. Search for WIMPs in liquid argon

    CERN Document Server

    Amsler, C

    2011-01-01

    Our group from the University of Zurich is performing R&D work towards the design of a large liquid argon detector to detect Weakly Interacting Massive Particles (WIMPs). This project is developed within the DARWIN Collaboration funded by ASPERA to prepare a proposal for the next generation of WIMP searches using noble liquids. We are performing R&D to detect the VUV light from recoiling argon nuclei. Results obtained with one ton of liquid argon (ArDM prototype) and prospects using a monoenergetic neutron source are discussed.

  10. In vitro study of safety and co-efficiency of the transbronchial coagulation techniques

    Institute of Scientific and Technical Information of China (English)

    BAI Chong; DONG Yu-chao; SONG Xiao-lian; HUANG Yi; SHI Hui; HU Zhen-li; LI Qiang

    2013-01-01

    Background The usual transbronchial coagulation techniques include microwave,argon plasma coagulation (APC),electrocautery and cryotherapy.However,there are serious clinical problems in the safety of each.By analyzing the experimental data and clinical observations,we observed the variable effects of different coagulation techniques via bronchofibroscopy,to look for an optimal interventional management of luminal bronchus diseases,and evaluate the safety and the equivalent point.Methods Four kinds of coagulation techniques under bronchoscopy were performed on the fresh bronchus of healthy sheep,and the pathologic changes in all groups were observed under the microscope.The different treatment parameters were as follows:microwave 60 W×1 second,3 seconds,5 seconds and 40 W×1 second,3 seconds,5 seconds; APC 40 W×1 second,3 seconds,5 seconds; electrocautery 40 W×1 second,3 seconds,5 seconds;cryotherapy 100 Ω×60 seconds,120 seconds.Results After treatment,ovine bronchial mucosa in all groups showed pathologic changes such as local necrosis and amotio of the mucosa lining epithelium,local submucosa coagulative necrosis or tissue defects,while inflammation in the surrounding tissue was not obvious.Under the same output power and action time,different methods had different outcomes.The damage by APC was the most superficial,microwave was the second,and electrocautery caused the worst damage.The study also found that effects of electrocautery at 40 W×3 seconds,microwave at 40 W×5 seconds or 60 W×3 seconds,APC at 40 W×5 seconds and cryotherapy at 100 Ω×120 seconds were the equivalent point conditions.The appearance included mucosa absence,partial submucosa absence,and collagen fiber coagulation in treatment areas.Conclusions Each coagulation technique has its own characteristic.It is very important to choose the appropriate power and action time of the suitable method according to the therapy requirement.

  11. Blood coagulation using High Intensity Focused Ultrasound (HIFU)

    Science.gov (United States)

    Nguyen, Phuc V.; Oh, Junghwan; Kang, Hyun Wook

    2014-03-01

    High Intensity Focused Ultrasound (HIFU) technology provides a feasible method of achieving thermal coagulation during surgical procedures. One of the potential clinical benefits of HIFU can induce immediate hemostasis without suturing. The objective of this study was to investigate the efficiency of a HIFU system for blood coagulation on severe vascular injury. ngHIFU treatment was implemented immediately after bleeding in artery. The ultrasound probe was made of piezoelectric material, generating a central frequency of 2.0 MHz as well as an ellipsoidal focal spot of 2 mm in lateral dimension and 10 mm in axial dimension. Acoustic coagulation was employed on a perfused chicken artery model in vitro. A surgical incision (1 to 2 mm long) was made with a scapel on the arterial wall, and heparinized autologous blood was made to leak out from the incision with a syringe pump. A total of 5 femoral artery incisions was treated with the HIFU beam. The intensity of 4500 W/cm2 at the focus was applied for all treatments. Complete hemostasis was achieved in all treatments, along with the treatment times of 25 to 50 seconds. The estimated intraoperative blood loss was from 2 to 5 mL. The proposed HIFU system may provide an effective method for immediate blood coagulation for arteries and veins in clinical applications.

  12. Opacity of Shock-Generated Argon Plasmas

    Institute of Scientific and Technical Information of China (English)

    王藩侯; 陈敬平; 周显明; 李西军; 经福谦; 孟续军; 孙永盛

    2001-01-01

    Argon plasmas with uniform density and temperature are generated by a planar shock wave through argon gas. The opacities of argon plasma, covering the thermodynamic states at temperatures of 1.4-2.2eV and in densities of 0.0083- 0.015 g/cm3, are investigated by measuring the emitted radiance versus time at several visible wavelengths. Comparison of the measured opacities with those calculated demonstrates that the average atom model can be used well to describe the essential transport behaviour of photons in argon plasma under the abovementioned thermodynamic condition. A simplified and self-consistent method to deduce the reflectivity R(λ) at the baseplate surface is applied. It demonstrates that the values of R(λ) are all around 0.4 in the experiments, which are basically in agreement with those given by Erskine previously (1994 J. Quant. Spectrosc. Radiat.Transfer 51 97).

  13. Clinical periodontics with the argon laser

    Science.gov (United States)

    Finkbeiner, R. L.

    1995-04-01

    The argon laser has proven to be a valuable tool for the thermodynamic debridement of the periodontal lesion, incisions and tissue fusion. Illustrations of clinical applications and discussion of laser parameters will be provided.

  14. Depinning as a coagulation process

    Science.gov (United States)

    İşeri, M.; Kaspar, D.; Mungan, M.

    2016-08-01

    We consider a one-dimensional model that describes the depinning of an elastic string of particles in a strongly pinning, phase-disordered periodic environment under a slowly increasing force. The evolution towards depinning occurs by the triggering of avalanches in regions of activity which are at first isolated, but later grow and merge. For large system sizes the dynamically critical behavior is dominated by the coagulation of these active regions. Our analysis and numerical simulations show that the evolution of the sizes of active regions is well described by a Smoluchowski coagulation equation, allowing us to predict correlation lengths and avalanche sizes in terms of certain moments of the size distribution.

  15. Argon Laser Photoablation for Postburn Conjunctival Pigmentation

    Directory of Open Access Journals (Sweden)

    Seong Joon Ahn

    2014-01-01

    Full Text Available We report a case of an ocular burn injury from boiling water which resulted in conjunctival pigmentation, 1 week following injury. For cosmetic purposes, 2 sessions of argon laser photoablation were performed. One month after laser treatment, conjunctival pigmentation had been successfully removed and the patient was very satisfied with the results. Argon laser photoablation may be an effective way to remove postburn conjunctival pigmentation.

  16. Coagulation/Flocculation of Tannery Wastewater Using Immobilized Chemical Coagulants

    Directory of Open Access Journals (Sweden)

    Q. Imran

    2012-04-01

    Full Text Available Chemical coagulants were immobilized into bead form using sodium alginate to treat tannery wastewater samples. The used chemical coagulants were ammonium aluminium sulphate (NH4Al(SO42, aluminium sulphate (Al2(SO42, calcium carbonate (CaCO3, sodium citrate (Na3C6HsO7. The effect of the chemical coagulant dose and tannery wastewater pH was studied on wastewater electrical conductance (EC, total dissolved solids (TDS, sulphates, chlorides, phenolphthalein alkalinity, total alkalinity and chemical oxygen demand (COD. The quantity of various pollutants present in waste water was reduced after treatment. The optimized dose and pH for maximum decrease in EC and TDS were 5g/L and 7, respectively. The maximum reduction in the amount of sulphates and chlorides present in tannery wastewater was observed at dosage of 0.5g/L and pH 7. A dosage of 5g/L and pH 7 was also found most favorable for maximum reduction in values of COD, phenolphtalein and total alkalinity. The chromium concentrations in tannery wastewater before and after treatment were determined by atomic absorption spectrophotometer. A reduction in chromium concentration was observed after treatment. The promising results of the present study demonstrate that immobilization of chemical coagulants can make them more effective for wastewater treatment.

  17. 21 CFR 864.5400 - Coagulation instrument.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Coagulation instrument. 864.5400 Section 864.5400 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND HUMAN SERVICES (CONTINUED....5400 Coagulation instrument. (a) Identification. A coagulation instrument is an automated or...

  18. Potassium-argon/argon-40-argon-39 geochronology of Cenozoic alkali basalts from the South China Sea

    Institute of Scientific and Technical Information of China (English)

    YAN Quanshu; SHI Xuefa; YANG Yaomin; WANG Kunshan

    2008-01-01

    Based on the isotopic chronologic results of Cenozoic alkali basalts from the South China Sea,the characteristics of volcanic activi-ty of the South China Sea after spreading were studied.The potassium - argon ages of eight alkali basalt samples from the South China Sea,and the argon - argon ages of two samples among them are reported.Apparent ages of the whole rock are 3.80 to 7.91 Ma with an average value of 5.43 Ma (potassium- argon,whole rock),and there is little difference among samples at the same location,e.g.,4.76~5.78 Ma for location S04-12.The argon - argon ages for the two samples are 6.06 and 4.71 Ma,which lie within the age scope of potassium - argon method.The dating results indicate that rock-forming age is from late Miocene to Pli-ocene,which is consistent with erupting event for alkali basalts from adjacent regions of the South China Sea.Volcanic activities occur after the cessation of spreading of the South China Sea,which are controlled by lithospheric fault and the spreading center formed during the spreading period of the South China Sea.These dating results,combined with geochemical characteristics of these basalts,the published chronological data for the South China Sea and its adjacent regions,and the updated geophysical data near Hainan Island,suggest that after the cessation of spreading of the South China Sea,there occur widely distributing magmatic activities which primarily is alkali basalt,and the volcanic activity continues to Quaternary.The activity may be relative to Hainan mantle plume originated from core/mantle boundary.

  19. Argon Collection And Purification For Proliferation Detection

    Energy Technology Data Exchange (ETDEWEB)

    Achey, R. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL); Hunter, D. [Savannah River Site (SRS), Aiken, SC (United States). Savannah River National Lab. (SRNL)

    2015-10-09

    In order to determine whether a seismic event was a declared/undeclared underground nuclear weapon test, environmental samples must be taken and analyzed for signatures that are unique to a nuclear explosion. These signatures are either particles or gases. Particle samples are routinely taken and analyzed under the Comprehensive Nuclear-Test-Ban Treaty Organization (CTBTO) verification regime as well as by individual countries. Gas samples are analyzed for signature gases, especially radioactive xenon. Underground nuclear tests also produce radioactive argon, but that signature is not well monitored. A radioactive argon signature, along with other signatures, can more conclusively determine whether an event was a nuclear test. This project has developed capabilities for collecting and purifying argon samples for ultra-low-background proportional counting. SRNL has developed a continuous gas enrichment system that produces an output stream containing 97% argon from whole air using adsorbent separation technology (the flow diagram for the system is shown in the figure). The vacuum swing adsorption (VSA) enrichment system is easily scalable to produce ten liters or more of 97% argon within twelve hours. A gas chromatographic separation using a column of modified hydrogen mordenite molecular sieve has been developed that can further purify the sample to better than 99% purity after separation from the helium carrier gas. The combination of these concentration and purification systems has the capability of being used for a field-deployable system for collecting argon samples suitable for ultra-low-background proportional counting for detecting nuclear detonations under the On-Site Inspection program of the CTBTO verification regime. The technology also has applications for the bulk argon separation from air for industrial purposes such as the semi-conductor industry.

  20. Conclusive evidence of abrupt coagulation inside the void during cyclic nanoparticle formation in reactive plasma

    Science.gov (United States)

    van de Wetering, F. M. J. H.; Nijdam, S.; Beckers, J.

    2016-07-01

    In this letter, we present scanning electron microscopy (SEM) results that confirm in a direct way our earlier explanation of an abrupt coagulation event as the cause for the void hiccup. In a recent paper, we reported on the fast and interrupted expansion of voids in a reactive dusty argon-acetylene plasma. The voids appeared one after the other, each showing a peculiar, though reproducible, behavior of successive periods of fast expansion, abrupt contraction, and continued expansion. The abrupt contraction was termed "hiccup" and was related to collective coagulation of a new generation of nanoparticles growing in the void using relatively indirect methods: electron density measurements and optical emission spectroscopy. In this letter, we present conclusive evidence using SEM of particles collected at different moments in time spanning several growth cycles, which enables us to follow the nanoparticle formation process in great detail.

  1. Argon ion beam induced surface pattern formation on Si

    Energy Technology Data Exchange (ETDEWEB)

    Hofsäss, H.; Bobes, O.; Zhang, K. [2nd Institute of Physics, Faculty of Physics, University Göttingen, Friedrich-Hund-Platz 1, 37077 Göttingen (Germany)

    2016-01-21

    The development of self-organized surface patterns on Si due to noble gas ion irradiation has been studied extensively in the past. In particular, Ar ions are commonly used and the pattern formation was analyzed as function of ion incidence angle, ion fluence, and ion energies between 250 eV and 140 keV. Very few results exist for the energy regime between 1.5 keV and 10 keV and it appears that pattern formation is completely absent for these ion energies. In this work, we present experimental data on pattern formation for Ar ion irradiation between 1 keV and 10 keV and ion incidence angles between 50° and 75°. We confirm the absence of patterns at least for ion fluences up to 10{sup 18} ions/cm{sup 2}. Using the crater function formalism and Monte Carlo simulations, we calculate curvature coefficients of linear continuum models of pattern formation, taking into account contribution due to ion erosion and recoil redistribution. The calculations consider the recently introduced curvature dependence of the erosion crater function as well as the dynamic behavior of the thickness of the ion irradiated layer. Only when taking into account these additional contributions to the linear theory, our simulations clearly show that that pattern formation is strongly suppressed between about 1.5 keV and 10 keV, most pronounced at 3 keV. Furthermore, our simulations are now able to predict whether or not parallel oriented ripple patterns are formed, and in case of ripple formation the corresponding critical angles for the whole experimentally studied energies range between 250 eV and 140 keV.

  2. Attenuation of vacuum ultraviolet light in liquid argon

    CERN Document Server

    Neumeier, A; Oberauer, L; Potzel, W; Schönert, S; Dandl, T; Heindl, T; Ulrich, A; Wieser, J

    2015-01-01

    The transmission of liquid argon has been measured, wavelength resolved, for a wavelength interval from 118 to 250 nm. The wavelength dependent attenuation length is presented for pure argon. It is shown that no universal wavelength independent attenuation length can be assigned to liquid argon for its own fluorescence light due to the interplay between the wavelength dependent emission and absorption. A decreasing transmission is observed below 130 nm in both chemically cleaned and distilled liquid argon and assigned to absorption by the analogue of the first argon excimer continuum. For not perfectly cleaned argon a strong influence of impurities on the transmission is observed. Two strong absorption bands at 126.5 and 141.0 nm with approximately 2 and 4 nm width, respectively, are assigned to traces of xenon in argon. A broad absorption region below 180 nm is found for unpurified argon and tentatively attributed to the presence of water in the argon sample.

  3. Kinetic modeling of the Townsend breakdown in argon

    Energy Technology Data Exchange (ETDEWEB)

    Macheret, S. O.; Shneider, M. N. [Department of Mechanical and Aerospace Engineering, Princeton University, D-414 Engineering Quadrangle, Princeton, New Jersey 08544 (United States)

    2013-10-15

    Kinetic modeling of the Townsend breakdown in argon was performed in the “forward-back” approximation. The kinetic model was found to adequately describe the left branch of the Paschen curve, and the important role of ionization by fast ions and atoms near the cathode, as well as the increase in secondary emission coefficient in strong electric fields described in the literature, was confirmed. The modeling also showed that the electron energy distribution function develops a beam of high-energy electrons and that the runaway effect, i.e., the monotonic increase of the mean electron energy with the distance from the cathode, occurs at the left branch of the Paschen curve.

  4. LArIAT: Worlds First Pion-Argon Cross-Section

    Energy Technology Data Exchange (ETDEWEB)

    Hamilton, Pip [Fermilab

    2016-11-02

    The LArIAT experiment has performed the world's first measurement of the total charged-current pion cross-section on an argon target, using the repurposed ArgoNeuT detector in the Fermilab test beam. Presented here are the results of that measurement, along with an overview of the LArIAT experiment and details of the LArIAT collaboration's plans for future measurements.

  5. LArIAT: Worlds First Pion-Argon Cross-Section

    CERN Document Server

    Hamilton, Pip

    2016-01-01

    The LArIAT experiment has performed the world's first measurement of the total charged-current pion cross-section on an argon target, using the repurposed ArgoNeuT detector in the Fermilab test beam. Presented here are the results of that measurement, along with an overview of the LArIAT experiment and details of the LArIAT collaboration's plans for future measurements.

  6. Table-top setup for investigating the scintillation properties of liquid argon

    CERN Document Server

    Heindl, T; Fedenev, A; Hofmann, M; Krücken, R; Oberauer, L; Potzel, W; Wieser, J; Ulrich, A

    2015-01-01

    The spectral and temporal light emission properties of liquid argon have been studied in the context of its use in large liquid rare-gas detectors for detecting Dark Matter particles in astronomy. A table-top setup has been developed. Continuous and pulsed low energy electron beam excitation is used to stimulate light emission. A spectral range from 110 to 1000 nm in wavelength is covered by the detection system with a time resolution on the order of 1 ns.

  7. Trapping cold ground state argon atoms.

    Science.gov (United States)

    Edmunds, P D; Barker, P F

    2014-10-31

    We trap cold, ground state argon atoms in a deep optical dipole trap produced by a buildup cavity. The atoms, which are a general source for the sympathetic cooling of molecules, are loaded in the trap by quenching them from a cloud of laser-cooled metastable argon atoms. Although the ground state atoms cannot be directly probed, we detect them by observing the collisional loss of cotrapped metastable argon atoms and determine an elastic cross section. Using a type of parametric loss spectroscopy we also determine the polarizability of the metastable 4s[3/2](2) state to be (7.3±1.1)×10(-39)  C m(2)/V. Finally, Penning and associative losses of metastable atoms in the absence of light assisted collisions, are determined to be (3.3±0.8)×10(-10)  cm(3) s(-1).

  8. Effect of argon during diamond deposition

    Energy Technology Data Exchange (ETDEWEB)

    Barbosa, D.C.; Mengui, U.A.; Contin, A.; Trava-Airoldi, V.J.; Baldan, M.R.; Corat, E.J. [Instituto Nacional de Pesquisas Espaciais (INPE), Sao Jose dos Campos, SP (Brazil). Laboratorio Associado de Sensores e Materiais

    2014-07-01

    The effect of argon content upon the growth rate and the properties of diamond thin films grown with different grains sizes is explored. An argon-free and argon-rich gas mixture of methane and hydrogen is used in a hot filament chemical vapor deposition reactor. Characterization of the films is accomplished by scanning electron microscopy, Raman spectroscopy and high-resolution x-ray diffraction. An extensive comparison of the growth rate values obtained in this study with those found in the literature suggests that there are distinct common trends for microcrystalline and nanocrystalline diamond growth, despite a large variation in the gas mixture composition. Included is a discussion of the possible reasons for these observations. (author)

  9. Treatment of Disseminated Intravascular Coagulation.

    Science.gov (United States)

    Makruasi, Nisa

    2015-11-01

    Disseminated intravascular coagulation (DIC) is a syndrome characterized by systemic activation of blood coagulation, generation of thrombin, and leading to disturbance of the microvasculature. In this article, definition and diagnostic criteria of DIC depend on the International Society of Thrombosis and Haemostasis (ISTH). There is no gold standard for diagnosis of DIC, only low quality evidence is used in general practice. Many diagnostic tests and repeated measurement are required. For the treatment of DIC, there is no good quality evidence. The most important treatment for DIC is the specific treatment of the conditions associated DIC. Platelets and/or plasma transfusion may be also necessary if indicated. Nevertheless, there is no gold standard for diagnosis and treatment of DIC, we use only low quality evidence in general practice.

  10. Comparison of GEANT4 Simulations with Testbeam Data and GEANT3 for the ATLAS Liquid Argon Calorimeter

    Institute of Scientific and Technical Information of China (English)

    D.Benchekroun; G.Karapetian; 等

    2001-01-01

    We present several comparisons of GEANT4 simulations with test beam data and GEANT3 simulations for different liquid argon(LAr) calorimeters of the ATLAS detector,All relevant parts of the test beam setup(scintilators,multi wire proportional chambers,cryostat etc.)are described in GEANT4 as well as in GEANT3.Muon and electron data at different energies have been compared with Monte Carlo prediction.

  11. Comparison of coagulation performance and floc properties using a novel zirconium coagulant against traditional ferric and alum coagulants.

    Science.gov (United States)

    Jarvis, Peter; Sharp, Emma; Pidou, Marc; Molinder, Roger; Parsons, Simon A; Jefferson, Bruce

    2012-09-01

    Coagulation in drinking water treatment has relied upon iron (Fe) and aluminium (Al) salts throughout the last century to provide the bulk removal of contaminants from source waters containing natural organic matter (NOM). However, there is now a need for improved treatment of these waters as their quality deteriorates and water quality standards become more difficult to achieve. Alternative coagulant chemicals offer a simple and inexpensive way of doing this. In this work a novel zirconium (Zr) coagulant was compared against traditional Fe and Al coagulants. The Zr coagulant was able to provide between 46 and 150% lower dissolved organic carbon (DOC) residual in comparison to the best traditional coagulant (Fe). In addition floc properties were significantly improved with larger and stronger flocs forming when the Zr coagulant was used with the median floc sizes being 930 μm for Zr; 710 μm for Fe and 450 μm for Al. In pilot scale experiments, a similar improved NOM and particle removal was observed. The results show that when optimised for combined DOC removal and low residual turbidity, the Zr coagulant out-performed the other coagulants tested at both bench and pilot scale.

  12. Positive and negative pulsed corona in argon

    NARCIS (Netherlands)

    Veldhuizen, E.M. van; Rutgers, W.R.; Ebert, U.

    2002-01-01

    Photographs are obtained of corona discharges in argon at atmospheric pressure using a high resolution, intensified CCD camera. Positive and negative polarity is applied at the curved electrode in a point-plane gap and a plane-plane gap with a protruding point. Branching is observed in the positive

  13. Thermal decomposition of barium valerate in argon

    DEFF Research Database (Denmark)

    Torres, P.; Norby, Poul; Grivel, Jean-Claude

    2015-01-01

    The thermal decomposition of barium valerate (Ba(C4H9CO2)(2)/Ba-pentanoate) was studied in argon by means of thermogravimetry, differential thermal analysis, IR-spectroscopy, X-ray diffraction and hot-stage optical microscopy. Melting takes place in two different steps, at 200 degrees C and 280...

  14. 46 CFR 151.50-36 - Argon or nitrogen.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 5 2010-10-01 2010-10-01 false Argon or nitrogen. 151.50-36 Section 151.50-36 Shipping... BULK LIQUID HAZARDOUS MATERIAL CARGOES Special Requirements § 151.50-36 Argon or nitrogen. (a) A cargo tank that contains argon or nitrogen and that has a maximum allowable working pressure of 172 kPa...

  15. Microwave diagnostic for the determination of the electron temperature of a low density shock-heated argon plasma

    Science.gov (United States)

    Schneider, C. P.; Exberger, R. J.

    1978-01-01

    The diffraction, defocusing and beam bending effects of microwaves transmitted through a bounded shock-heated argon plasma with low electron density are investigated with the purpose of developing an accurate method for electron temperature (Te) determination. This report describes the evaluation technique and presents results for an argon plasma with pressure between 3 and 10 torr, and T2 between 5500 and 9500 K. The electron temperature values obtained have a range of uncertainty between -20% and +10% only. The electron temperature is equal or lower by approximately 1000 K in comparison to the heavy particle temperature (T2).

  16. Pulse Shape Discrimination in liquid argon and its implications for Dark Matter searches using depleted argon

    CERN Document Server

    Kryczynski, Pawel

    2012-01-01

    A brief outline of Dark Matter detection experiments using liquid argon technology is presented. The Pulse Shape background discrimination method (PSD) is described and the example of its use in 2.3 l R&D detector is given. Methods of calculating sensitivity of a Dark Matter detector are discussed and used to estimate the possible improvement of sensitivity after introduction of isotopically depleted liquid argon.

  17. Coagulation factor Xa signaling : the link between coagulation and inflammatory bowel disease?

    NARCIS (Netherlands)

    Borensztajn, Keren; Peppelenbosch, Maikel P.; Spek, C. Arnold

    2009-01-01

    Inflammatory bowel disease (IBD) is characterized by activation of the coagulation cascade and it has long been suspected that coagulation is an essential component of this still largely idiopathic group of diseases. The realization that coagulation factors are not only passive mediators in the prop

  18. Imaging of hydrogen halides photochemistry on argon and ice nanoparticles

    Energy Technology Data Exchange (ETDEWEB)

    Poterya, V., E-mail: poterya@jh-inst.cas.cz; Lengyel, J.; Pysanenko, A.; Svrčková, P.; Fárník, M., E-mail: michal.farnik@jh-inst.cas.cz [J. Heyrovský Institute of Physical Chemistry v.v.i., Academy of Sciences of the Czech Republic, Dolejškova 3, 18223 Prague (Czech Republic)

    2014-08-21

    The photodissociation dynamics of HX (X = Cl, Br) molecules deposited on large Ar{sub N} and (H{sub 2}O){sub N}, N{sup ¯}≈ 10{sup 2}–10{sup 3}, clusters is investigated at 193 nm using velocity map imaging of H and Cl photofragments. In addition, time-of-flight mass spectrometry after electron ionization complemented by pickup cross section measurements provide information about the composition and structure of the clusters. The hydrogen halides coagulate efficiently to generate smaller (HX){sub n} clusters on Ar{sub N} upon multiple pickup conditions. This implies a high mobility of HX molecules on argon. On the other hand, the molecules remain isolated on (H{sub 2}O){sub N}. The photodissociation on Ar{sub N} leads to strong H-fragment caging manifested by the fragment intensity peaking sharply at zero kinetic energy. Some of the Cl-fragments from HCl photodissociation on Ar{sub N} are also caged, while some of the fragments escape the cluster directly without losing their kinetic energy. The images of H-fragments from HX on (H{sub 2}O){sub N} also exhibit a strong central intensity, however, with a different kinetic energy distribution which originates from different processes: the HX acidic dissociation followed by H{sub 3}O neutral hydronium radical formation after the UV excitation, and the slow H-fragments stem from subsequent decay of the H{sub 3}O. The corresponding Cl-cofragment from the photoexcitation of the HCl·(H{sub 2}O){sub N} is trapped in the ice nanoparticle.

  19. Genetic engineering and coagulation factors.

    Science.gov (United States)

    Fass, D N; Toole, J J

    1985-06-01

    It is unfortunate that we cannot report, in the area of coagulation, advances that have been seen in related fields such as thrombolytic therapy. The reported progress (Gold et al, 1984; Van de Werf et al, 1984) with human recombinant tissue plasminogen activator (Pennica et al, 1983) augers well for the application of recombinant technology to the problems faced by patients with coagulation defects. While plasminogen activator is being assessed in an acute therapeutic setting, its use signals a beginning of the application of the technology to abnormalities of the haemostatic mechanism. Chronic administration of coagulation factors for prophylaxis and replacement therapy would appear to be just one more step down the pathway illuminated by the biochemists, microbiologists and cell biologists who have preceded the clinicians in this promising area. There is no record of the use of genetically engineered materials in the treatment of coagulation defects, primarily because the body of knowledge and refined techniques have only recently been acquired. For this reason we have had to project developments in other areas onto the problems that exist for the haemostatically compromised patient. In describing the potential usefulness of these technologies, it is difficult to ascertain where the logical projection, from a fully investigated model system, diverges from flights of imaginative fancy. Cloning projects considered overly ambitious and grandiose at the beginning of this decade are already accomplished feats. The feasibility of gene therapy in the mammalian system has been demonstrated, and trade publications now discuss governmental approval for investigative use of this procedure in 1985. Panels of physicians, scientists and even politicians now seriously contemplate and promulgate views and regulations pertaining to the efficacy and ethics of the use of genetic engineering in the treatment of human disease. The haemophilias will certainly be among the first

  20. challenges in management of warfarin anti-coagulation in advanced ...

    African Journals Online (AJOL)

    2013-07-01

    Jul 1, 2013 ... hyper-coagulable state in advanced HIV/AIDS patients has ... state in these patients with abnormalities in the coagulation ... Oral anti-coagulation therapy with warfarin ..... as stasis, trauma, or known hypercoagulability (e.g..

  1. Liquid argon scintillation light studies in LArIAT

    Energy Technology Data Exchange (ETDEWEB)

    Kryczynski, Pawel [Fermilab

    2016-10-12

    The LArIAT experiment is using its Liquid Argon Time Projection Chamber (LArTPC) in the second run of data-taking at the Fermilab Test Beam Facility. The goal of the experiment is to study the response of LArTPCs to charged particles of energies relevant for planned neutrino experiments. In addition, it will help to develop and evaluate the performance of the simulation, analysis, and reconstruction software used in other LAr neutrino experiments. Particles from a tertiary beam detected by LArIAT (mainly protons, pions and muons) are identified using a set of beamline detectors, including Wire Chambers, Time of Flight counters and Cherenkov counters, as well as a simplified sampling detector used to detect muons. In its effort towards augmenting LArTPC technology for other neutrino experiments, LArIAT also takes advantage of the scintillating capabilities of LAr and is testing the possibility of using the light signal to help reconstruct calorimetric information and particle ID. In this report, we present results from these studies of the scintillation light signal to evaluate detector performance and calorimetry.

  2. SC response characteristics of two kinds of coagulant

    Institute of Scientific and Technical Information of China (English)

    杨万东; 宋爽; 史惠祥

    2002-01-01

    Automatic coagulant dosage control with streaming current (SC) technique is introduced in this paper. Aluminum and ferric coagulants are widely used in surface water treatment. The SC response characteristics of P-AlCl3 aluminum coagulant and P-FeCl3 ferric coagulant were investigated in this work. Bench-scale water treatment results were obtained from jar tests including rapid mixing, flocculation and undisturbed sedimentation. Results showed that aluminum coagulant is more sensitive than ferric coagulant to SC response.

  3. SC response characteristics of two kinds of coagulant

    Institute of Scientific and Technical Information of China (English)

    杨万东; 宋爽; 史惠祥

    2002-01-01

    Automatic coagulant dosage control with streaming current (SC) technique is in troduced inthis paper. Aluminum and ferric coagulants are widely used in surface water treatment. The SC response characteristics of P-AiCI3 aluminum coagulant and P-FeCI3 ferric coagulant were investigated in this work. Bench-scale water treatment results were obtained from jar tests including rapid mixing,flocculation and undisturbed sedimentation. Results showed that aluminum coagulant is more sensitive than ferric coagulant to SC response.

  4. Coagulation and fibrinolysis during laparoscopic cholecystectomy

    DEFF Research Database (Denmark)

    Rahr, H B; Fabrin, K; Larsen, J F

    1999-01-01

    Laparoscopic surgery appears to be less traumatic to the patient than open surgery, but its influence upon coagulation and fibrinolysis is incompletely elucidated. Our aim was to measure markers of coagulation and fibrinolysis before, during. and after laparoscopic cholecystectomy (LC). Blood...

  5. Investigation of coagulation activity of natural coagulants from seeds of different leguminose species

    Directory of Open Access Journals (Sweden)

    Šćiban Marina B.

    2005-01-01

    Full Text Available The ability of seeds of plants: Phaseolus vulgaris, Robinia pseudoacacia Ceratonia siliqua and Amorpha fruticosa, to act as natural coagulants was tested using synthetic turbid water. This water was prepared by adding kaolin into tap water, just before the test. Active components were extracted from ground seeds with distilled water. The coagulation ability of this extract was assessed by the use of standard jar test measurements in water with various initial turbidity. Investigation of these natural coagulants was confirmed their positive coagulation activity. Of all plants that have been examined, the seed extract from Ceratonia siliqua appeared to be one of the most effective coagulants for water treatment. A dose of 20 mg/l of this coagulant resulted in 100% coagulation activity for clarification of water with 17.5 NTU initial turbidity.

  6. WA105: A large demonstrator of a liquid argon dual phase TPC

    Science.gov (United States)

    Zambelli, L.; Murphy, S.; WA105 Collaboration

    2017-09-01

    The Liquid argon technology has been chosen for the DUNE underground experiment for the study of neutrino oscillations, neutrino astrophysics and proton decay. This detector has excellent tracking and calorimetric capabilities much superior to currently operating neutrino detectors. WA105 is a large demonstrator of the dual-phase liquid argon TPC based on the GLACIER design, with a 6×6×6 m3 (appr. 300t) active volume. Its construction and operation test scalable solutions for the crucial aspects of this detector: ultra-high argon purity in non-evacuable tanks, long drifts, very high drift voltages, large area MPGD, cold preamplifiers. The TPC will be built inside a tank based on industrial LNG technology. Electrons produced in the liquid argon are extracted in the gas phase. Here, a readout plane based on Large Electron Multipliers (LEM’s) provides amplification before the charge collection onto an anode plane with strip readout. This highly cost effective solution provides excellent imaging capabilities with equal charge sharing on both views. PMTs located at the bottom of the tank containing the liquid argon provide the readout of the scintillation light. This demonstrator is an industrial prototype of the design proposed for a large underground detector. WA105 is under construction at CERN and will be exposed to a charged particle beam (0.5 - 20 GeV/c) in the North Area in 2018. The data will provide necessary calibration of the detector performances and benchmark sophisticated reconstruction algorithms. This project is a crucial milestone for the long baseline neutrino program DUNE.

  7. Quantifying interspecific coagulation efficiency of phytoplankton

    DEFF Research Database (Denmark)

    Hansen, J.L.S.; Kiørboe, Thomas

    1997-01-01

    Non-sticky latex beads and sticky diatoms were used as models to describe mutual coagulation between sticky and non-sticky particles. in mixed suspensions of beads and Thalassiosira nordenskjoeldii, both types of particles coagulated into mixed aggregates at specific rates, from which the intersp......Non-sticky latex beads and sticky diatoms were used as models to describe mutual coagulation between sticky and non-sticky particles. in mixed suspensions of beads and Thalassiosira nordenskjoeldii, both types of particles coagulated into mixed aggregates at specific rates, from which....... nordenskjoeldii. Mutual coagulation between Skeletonema costatum and the non-sticky cel:ls of Ditylum brightwellii also proceeded with hall the efficiency of S. costatum alone. The latex beads were suitable to be used as 'standard particles' to quantify the ability of phytoplankton to prime aggregation...

  8. Textile wastewater purification through natural coagulants

    Science.gov (United States)

    Beltrán-Heredia, J.; Sánchez-Martín, J.; Rodríguez-Sánchez, M. T.

    2011-09-01

    A new coagulant obtained through polymerization of Acacia mearnsii de Wild tannin extract has been characterized in the removal of two dangerous dye pollutants: Alizarin Violet 3R and Palatine Fast Black WAN. This coagulant is lab-synthesized according to the etherification of tannins with glycidyltrimethylammonium chloride and formaldehyde and its performance in dye removal in terms of efficiency was high. Reasonably low coagulant dosages (ca. 50 mg L-1) reaches high capacity levels (around 0.8 for Alizarin Violet 3R and 1.6 for Palatine Fast Black WAN mg dye mg-1 of coagulant) and pH and temperature are not extremely affecting variables. The systems coagulant dyes were successfully modeled by applying the Langmuir hypothesis. q max and b parameters were obtained with an adjusted correlation factor ( r 2) above 0.8.

  9. Argon gas flow through glass nanopipette

    Science.gov (United States)

    Takami, Tomohide; Nishimoto, Kiwamu; Goto, Tadahiko; Ogawa, Shuichi; Iwata, Futoshi; Takakuwa, Yuji

    2016-12-01

    We have observed the flow of argon gas through a glass nanopipette in vacuum. A glass nanopipette with an inner diameter of 100 nm and a shank length of 3 mm was set between vacuum chambers, and argon gas was introduced from the top of the nanopipette to the bottom. The exit pressure was monitored with an increase in entrance pressure in the range of 50-170 kPa. Knudsen flow was observed at an entrance pressure lower than 100 kPa, and Poiseuille flow was observed at an entrance pressure higher than 120 kPa. The proposed pressure-dependent gas flow method provides a means of evaluating the glass nanopipette before using it for various applications including nanodeposition to surfaces and femtoinjection to living cells.

  10. Abnormal epidermal changes after argon laser treatment

    Energy Technology Data Exchange (ETDEWEB)

    Neumann, R.A.; Knobler, R.M.; Aberer, E.; Klein, W.; Kocsis, F.; Ott, E. (Univ. of Vienna (Austria))

    1991-02-01

    A 26-year-old woman with a congenital port-wine stain on the forehead was treated three times at 2-month intervals with an argon laser. Six months after the last treatment, moderate blanching and mild scaling confined to the treated area was observed. A biopsy specimen of the treated area revealed a significant decrease in ectatic vessels. However, epidermal changes similar to those of actinic keratosis with disorganized cell layers and marked cytologic abnormalities were seen. Analysis of peripheral blood lymphocytes for a defect in DNA repair was negative. Multiple, argon laser-induced photothermal effects may be responsible for the changes observed in our case and may lead to premalignant epidermal transformation.

  11. Explanation of the memory effect in argon

    Directory of Open Access Journals (Sweden)

    Marković Vidosav

    2005-01-01

    Full Text Available Memory effect - the long time variation of the electrical breakdown time delay on the relaxation time td (τ was observed in argon 24 hours after relaxation times and explained by the long-lived metastable states remaining from the preceding glow. However, the quenching processes reducing the effective lifetime of metastable states several orders of magnitude below that relevant for the time scale of observation were neglected. By applying approximate gas phase models it was found that the early afterglow kinetics up to hundreds of milliseconds is dominated by the decay of molecular argon ions Ar2+ and the approximate value of their ambipolar diffusion coefficient is determined. After that, nitrogen atoms present as impurities and recombined on the cathode surface and/or field emission determine the breakdown time delay down to the cosmic rays and natural radioactivity level.

  12. Observation of the Dependence of Scintillation from Nuclear Recoils in Liquid Argon on Drift Field

    CERN Document Server

    Alexander, T; Cao, H; Cocco, A G; DeJongh, F; Fiorillo, G; Galbiati, C; Ghag, C; Grandi, L; Kendziora, C; Lippincott, W H; Loer, B; Love, C; Manenti, L; Martoff, C J; Meng, Y; Montanari, D; Mosteiro, P; Olvitt, D; Pordes, S; Qian, H; Rossi, B; Saldanha, R; Tan, W; Tatarowicz, J; Walker, S; Wang, H; Watson, A W; Westerdale, S; Yoo, J

    2013-01-01

    We have exposed a dual-phase Liquid Argon Time Projection Chamber (LAr-TPC) to a low energy pulsed narrowband neutron beam, produced at the Notre Dame Institute for Structure and Nuclear Astrophysics to study the scintillation light yield of recoiling nuclei in a LAr-TPC. A liquid scintillation counter was arranged to detect and identify neutrons scattered in the LAr-TPC target and to select the energy of the recoiling nuclei. We report the observation of a significant dependence on drift field of liquid argon scintillation from nuclear recoils of 11 keV. This observation is important because, to date, estimates of the sensitivity of noble liquid TPC dark matter searches are based on the assumption that electric field has only a small effect on the light yield from nuclear recoils.

  13. Nanometer-scale sharpening and surface roughening of ZnO nanorods by argon ion bombardment

    Energy Technology Data Exchange (ETDEWEB)

    Chatterjee, Shyamal, E-mail: shyamal@iitbbs.ac.in [School of Basic Sciences, Indian Institute of Technology, Bhubaneswar 751013 (India); Behera, Akshaya K. [School of Basic Sciences, Indian Institute of Technology, Bhubaneswar 751013 (India); Banerjee, Amarabha; Tribedi, Lokesh C. [Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400005 (India); Som, Tapobrata [Institute of Physics, Sachivalaya Marg, Bhubaneswar 751005 (India); Ayyub, Pushan, E-mail: pushan@tifr.res.in [Tata Institute of Fundamental Research, Homi Bhabha Road, Mumbai 400005 (India)

    2012-07-01

    We report the effects of exposing a hydrothermally grown, single crystalline ZnO nanorod array to a beam of 50 keV argon ions at room temperature. High resolution electron microscopy reveals that the ion bombardment results in a nanometer-scale roughening of the nanorod sidewalls, which were almost atomically flat in the pristine sample. Ion bombardment further causes the flat, Almost-Equal-To 100 nm diameter nanorod tips to get sharpened to ultrafine points less than 10 nm across. While tip sharpening is attributed to preferential sputtering, the formation of crystalline surface protuberances can be ascribed to surface instability due to curvature dependent sputtering and surface diffusion under argon-ion bombardment. Both the nanoscale roughening as well as the tip sharpening are expected to favorably impact a wide variety of applications, such as those involving catalysis, gas sensing, solar cells, field emission and gas discharge.

  14. An impact hypothesis for Venus argon anomalies

    Science.gov (United States)

    Kaula, W. M.; Newman, W. I.

    1997-03-01

    The Ar-36+38 argon-excess anomally of Venus has been hypothesized to have its origin in the impact of an outer solar system body of about 100-km diameter. A critical evaluation is made of this hypothesis and its competitors; it is judged that its status must for the time being remain one of 'Sherlock Holmes' type, in that something so improbable must be accepted when all alternatives are eliminated.

  15. Effects of argon ion irradiation on nucleation and growth of silver nanoparticles in a soda-glass matrix

    Directory of Open Access Journals (Sweden)

    P. Gangopadhyay

    2011-09-01

    Full Text Available The present article explores an experimental study for nucleation and non-equilibrium growth of silver nanoparticles in a soda-glass matrix. Ion-irradiation induced recoiling of silver atoms with argon ions (at energy 100 keV facilitates nucleation as well as growth of the silver nanoparticles in the soda-glass matrix. Small growth of the silver nanoparticles in the soda-glass matrix has been experimentally observed after the irradiation with higher fluences of the argon ions. Role of the argon ions for the evolution of the silver nanoparticles in the soda-glass matrix has been elucidated in the present report. With increase of the argon-ion fluences, while slight athermal growth of the silver nanoparticles has been estimated, drastic increase in the optical responses and Rutherford backscattering (RBS yields of the silver nanoparticles have been observed in the sample with the maximum fluences. Possible correlations of increase of argon-ion fluences and the observed experimental results (optical and RBS, in particular have been explained in this article. Although it has been demonstrated using the silver metal film on a soda-glass substrate as a model example, the non-equilibrium approach of nucleation and ion-beam controlled growth of metal nanoparticles in a matrix should be applicable to other immiscible systems as well.

  16. [Coagulation profiles during cardiac surgery].

    Science.gov (United States)

    Bitkova, E E; Zvereva, N Iu; Khvatov, V B; Chumakov, M V; Timerbaev, V Kh; Dublev, A V; Redkoborodyĭ, A V

    2014-01-01

    To evaluate patients' hemostasis after cardiac surgery using thromboelastometric and impedance aggregometry. 66 patients were examined intraoperatively. Comparison group included 45 blood donors. Hemostasis was tested for thromboelastometricRotem Gamma with the assessment of external (exTem) and internal (inTem) pathways of coagulation tests performed detection of heparin (hepTem) and cytochalasin-D-inactivation of platelets (fibTem) to assess the level of fibrinogen. Collagen-induced platelet aggregation was determined in an aggregometer CHRONO-LOG (USA). Significant deviations of the parameters of hemostasis were detected in 52 of the 66 studied patients. In group-1 (23 patients) revealed a residual effect of heparin. The effect manifested prolongation CT (clotting time) inTem to an average of 241 +/- 15 s, compared with CT hepTem--181 +/- 7. Patients in this group were in need of additional administration of protamine sulfate. Postoperative bleeding and resternotomia were observed in 3 patients of group-1. In group-2 (25 patients) CT inTem was 216 +/- 21 with significantly fewer CT hepTem (272 +/- 26). The data indicated excess of protamine sulfate. Platelets aggregation decreased compared to the norm. According to the obtained results, the addition of protamine sulfate is not required, however, in 7 cases the protamine sulfate was administered in a dose of 8.9 +/- 0.8 mg in 6 cases resternotomiya required. In the third group (n = 6) bleeding was observed in 4 patients. The difference in CT-hepCT was significant. Significant variations were revealed in the tests of the activity of the extrinsic pathway of coagulation and cytochalasin-D-induced inactivation of platelets: exMCF- 42 +/- 2 mm (normal 57 +/- 15 mm), fibMCF 5.0 +/- 0.3 mm (norm 12.8 +/- 4.3 mm). The concentration of platelets and their aggregation activity was sharply reduced. Disorders of hemostasis in the third group, designated as dilution coagulopathy. Turning thromboelastometric and impedance

  17. Enhanced coagulation for high alkalinity and micro-polluted water: the third way through coagulant optimization.

    Science.gov (United States)

    Yan, Mingquan; Wang, Dongsheng; Qu, Jiuhui; Ni, Jinren; Chow, Christopher W K

    2008-04-01

    Conventional coagulation is not an effective treatment option to remove natural organic matter (NOM) in water with high alkalinity/pH. For this type of water, enhanced coagulation is currently proposed as one of the available treatment options and is implemented by acidifying the raw water and applying increased doses of hydrolyzing coagulants. Both of these methods have some disadvantages such as increasing the corrosive tendency of water and increasing cost of treatment. In this paper, an improved version of enhanced coagulation through coagulant optimization to treat this kind of water is demonstrated. A novel coagulant, a composite polyaluminum chloride (HPAC), was developed with both the advantages of polyaluminum chloride (PACl) and the additive coagulant aids: PACl contains significant amounts of highly charged and stable polynuclear aluminum hydrolysis products, which is less affected by the pH of the raw water than traditional coagulants (alum and ferric salts); the additives can enhance both the charge neutralization and bridging abilities of PACl. HPAC exhibited 30% more efficiency than alum and ferric salts in dissolved organic carbon (DOC) removal and was very effective in turbidity removal. This result was confirmed by pilot-scale testing, where particles and organic matter were removed synergistically with HPAC as coagulant by sequential water treatment steps including pre-ozonation, coagulation, flotation and sand filtration.

  18. Coagulation abnormalities in the cirrhotic patient.

    Science.gov (United States)

    Muciño-Bermejo, Jimena; Carrillo-Esper, Raúl; Uribe, Misael; Méndez-Sánchez, Nahum

    2013-01-01

    The clotting process is a dynamic array of multiple processes which can be described in four phases: platelet plug initiation and formation, clotting process propagation by the coagulation cascade, clotting termination by antithrombotic mechanisms and clot removal by fibrinolysis. The liver plays a central role in each of these phases of clotting process, as it synthesizes the majority of coagulation factors and proteins involved in fibrinolysis as well as thrombopoeitin, which is responsible for platelet production from megakaryocytes. Many pathological processes associated with cirrhosis, such as portal hypertension and endothelial dysfunction, as well as co-morbid conditions, may also alter the coagulation process. Consequently, patients with liver disease have a disturbed balance of procoagulant and anti-coagulant factors which deviates from the normal coagulation cascade. This situation poses an additional problem in the diagnostic and therapeutic approach to this group of patients, since traditional coagulation test may not be reliable for assessing bleeding or thrombotic risk and traditional transfusional strategies may not be applicable in cirrhotic patients. In this article, we review the pathophysiological bases of coagulation abnormalities, in cirrhotic patients, the diagnostic therapeutic strategies to be followed and its impact on the clinical outcome in the cirrhotic patient.

  19. FORMATION OF CARBON NANOSTRUCTURES USING ACETYLENE, ARGON-ACETYLENE AND ARGON-HYDROGEN-ACETYLENE PLASMAS

    OpenAIRE

    Marcinauskas, Liutauras; Grigonis, Alfonsas; Valincius, Vitas

    2013-01-01

    The amorphous carbon films were deposited on silicon-metal substrates by plasma jet chemical vapor deposition (PJCVD) and plasma enchanted CVD (PECVD). PJCVD carbon films have been prepared at atmospheric pressure in argon-acetylene and argon-hydrogen-acetylene plasma mixtures. The films deposited in Ar-C2H2 plasma are attributed to graphite-like carbon films. The formation of the nanocrystalline graphite was obtained in Ar-H2-C2H2 plasma. Addition of the hydrogen gas lead to the ...

  20. Coagulation behavior of polyaluminum chloride:Effects of pH and coagulant dosage☆

    Institute of Scientific and Technical Information of China (English)

    Ning Wei; Zhongguo Zhang; Dan Liu; Yue Wu; Jun Wang; Qunhui Wang

    2015-01-01

    Coagulation mechanisms of polyaluminum chloride (PACl) at various dosages were studied using a conventional jar test at different final and initial pH values during treating kaolin suspension. The optimal final pH and dosages for PACl were obtained based on residual turbidity and zeta potential of flocs. The coagulation zones at various PACl dosages and solution pH values were developed and compared with those of alum. It is found that the optimal mechanism under acidic condition is charge neutralization, while alkaline condition wil facilitate the coagulation of PACl. Both charge neutralization coagulation and sweep coagulation can achieve high coagulation efficiency under the alkaline condition ranging from final pH 7.0 to 10.0. Stabilization, charge neutralization destabilization, restabilization and sweep zones occur successively with increasing PACl dosages with the final pH values fixed at 7.0 and 8.0, but restabilization zone disappears at final pH 10.0. When the final pH is not controlled and consequently decreases with increasing PACl dosage, no typical sweep zone can be observed and the coagulant efficiency decreases at high PACl dosage. It seems that the final pH is more meaningful than the initial pH for coagulation. Charge neutralization coagulation efficiency is dominated by zeta potential of flocs and PACl precipitates. The charge neutralization and sweep coagulation zones of PACl are broader in the ranges of coagulant dosage and pH than those of alum. The results are helpful for us to treat water and wastewa-ter using PACl and to understand the coagulation process of PACl.

  1. Argon diffusion from biotite at high temperature and pressure

    Institute of Scientific and Technical Information of China (English)

    陈道公; 贾命命; 李彬贤; 陆全明; 谢鸿森; 侯渭

    1995-01-01

    t The experiments of argon diffusion dynamics for biotite were carried out at 700 -1000℃ and 0.5 - 2,0 GPa and the diffusion coefficient and activation energy using different models have been calculated. The results indicate that the pressure does affect the argon diffusion and its effect is opposite to that of temperature. When p increases, the activation energy increases and diffusion coefficient decreases. The relation between pressure, closure temperature and cooling rate has been obtained. It is postulated that in low T and high p conditions, the argon diffusion from the environment to the system could occur and incur the appearance of the external argon in minerals.

  2. Argon laser treatment of central serous chorioretinopathy

    Directory of Open Access Journals (Sweden)

    Ting- Bing Fang

    2013-04-01

    Full Text Available AIM: To observe the efficacy of the argon laser photocoagulation treatment of central serous chorioretinopathy(CSC. METHODS: The treatment groups: 18 patients(18 eyes, argon laser photocoagulation and oral jolethin, vitamin B1, inosine and venoruton tablets. Control group: 18 patients(18 eyes, oral lecithin complex iodine, vitamin B1, inosine, venoruton tablets. Foveal thickness and neuroepithelial layer detachment range were measured by optical coherence tomography(OCTbefore treatment, after 1 month and 3 months post-operation to compare the decline in value of foveal thickness and neuroepithelial layer detachment range of the two groups. RESULTS: After 1 month of treatment, the decline in value of the center foveal thickness: the value of treatment group was 256±72μm; the value of the control group was 82±57μm, and the difference of the two groups, P <0.05; the decline in value of neuroepithelial layer detachment range: the value of the treatment group was 3 548±168μm, the value of the control group was 1 520±143μm, And the difference of the two groups, P<0.05. After three months of treatment, the decline in value of the center foveal thickness: the value of treatment group was 383±75μm, the value of the control group was 312±67 μm, and the difference of the two groups, P<0.05; decline in value of neuroepithelial layer detachment range: the value of the treatment group was 4 908±172μm, the value of the control group was 4 211±153μm, and the difference of the two groups, P <0.05. The differences were statistically significant between the treatment and the control groups(two independent samples t-test. CONCLUSION:Argon laser photocoagulation treatment of CSC is an effective treatment method and can significantly shorten the course.

  3. [New oral anticoagulants - influence on coagulation tests].

    Science.gov (United States)

    Simeon, L; Nagler, M; Wuillemin, W A

    2014-01-01

    The new oral anticoagulants (NOACs) represent alternative antithrombotic agents for prophylaxis and therapy of thromboembolic diseases. They act either by inhibition of the clotting factor Xa or IIa (thrombin). As a consequence, they influence several coagulation assays (for example prothrombin time, activated partial thromboplastin time). Because of the short half-life of these new agents, these changes show great variations in the course of 24 hours. Furthermore, there are significant differences of laboratory results depending on the used reagents. We explain the influence of apixaban, rivaroxaban (factor Xa inhibitors) and dabigatran (thrombin inhibitor) on the most commonly used coagulation assays. Besides we show that this influence depends on the way of action of the drug as well as on the principle of the coagulation assay. Being aware of this relationships helps to interpret the results of coagulation assays under influence of NOACs correctly.

  4. Coagulation testing in the perioperative period

    Directory of Open Access Journals (Sweden)

    Venkatesan Thiruvenkatarajan

    2014-01-01

    Full Text Available Perioperative coagulation management is a complex task that has a significant impact on the perioperative journey of patients. Anaesthesia providers play a critical role in the decision-making on transfusion and/or haemostatic therapy in the surgical setting. Various tests are available in identifying coagulation abnormalities in the perioperative period. While the rapidly available bedside haemoglobin measurements can guide the transfusion of red blood cells, blood product administration is guided by many in vivo and in vitro tests. The introduction of newer anticoagulant medications and the implementation of the modified in vivo coagulation cascade have given a new dimension to the field of perioperative transfusion medicine. A proper understanding of the application and interpretation of the coagulation tests is vital for a good perioperative outcome.

  5. SIMULATION MODELING SLOW SPATIALLY HETER- OGENEOUS COAGULATION

    Directory of Open Access Journals (Sweden)

    P. A. Zdorovtsev

    2013-01-01

    Full Text Available A new model of spatially inhomogeneous coagulation, i.e. formation of larger clusters by joint interaction of smaller ones, is under study. The results of simulation are compared with known analytical and numerical solutions.

  6. Near-infrared scintillation of liquid argon

    Energy Technology Data Exchange (ETDEWEB)

    Alexander, T. [Fermilab; Escobar, C. O. [Campinas State U.; Lippincott, W. H. [Fermilab; Rubinov, P. [Fermilab

    2016-03-03

    Since the 1970s it has been known that noble gases scintillate in the near infrared (NIR) region of the spectrum (0.7 $\\mu$m < $\\lambda$; < 1.5$\\mu$m). More controversial has been the question of the NIR light yield for condensed noble gases. We first present the motivation for using the NIR scintillation in liquid argon detectors, then briefly review early as well as more recent efforts and finally show encouraging preliminary results of a test performed at Fermilab.

  7. Near-infrared scintillation of liquid argon

    CERN Document Server

    Alexander, T; Lippincott, W H; Rubinov, P

    2016-01-01

    Since the 1970s it has been known that noble gases scintillate in the near infrared (NIR) region of the spectrum (0.7 $\\mu$m < $\\lambda$; < 1.5$\\mu$m). More controversial has been the question of the NIR light yield for condensed noble gases. We first present the motivation for using the NIR scintillation in liquid argon detectors, then briefly review early as well as more recent efforts and finally show encouraging preliminary results of a test performed at Fermilab.

  8. Argon isotope fractionation induced by stepwise heating

    Science.gov (United States)

    Trieloff, Mario; Falter, Martina; Buikin, Alexei I.; Korochantseva, Ekaterina V.; Jessberger, Elmar K.; Altherr, Rainer

    2005-03-01

    Noble gas isotopes are widely used to elucidate the history of the rocks in which they have been trapped, either from distinct reservoirs or by accumulation following radioactive decay. To extract noble gases from their host rocks, stepwise heating is the most commonly used technique to deconvolve isotopically different components, e.g., atmospheric, in situ radiogenic, or excess radiogenic from mantle or crustal reservoirs. The accurate determination of the isotopic composition of these different components is of crucial importance, e.g., for ages obtained by 40Ar- 39Ar stepheating plateaus. However, diffusion theory-based model calculations predict that the stepwise thermal extraction process from mineral phases induces isotope fractionation and, hence, adulterates the original composition. Such effects are largely unconsidered, as they are small and a compelling experimental observation is lacking. We report the first unequivocal evidence for significant mass fractionation of argon isotopes during thermal extraction, observed on shungite, a carbon-rich Precambrian sedimentary rock. The degree of fractionation, as monitored by 38Ar/ 36Ar and 40Ar/ 36Ar ratios, very well agrees with theoretical predictions assuming an inverse square root dependence of diffusion coefficient and atomic mass, resulting in easier extraction of lighter isotopes. Hence, subatmospheric 40Ar/ 36Ar ratios obtained for argon extracted at low temperatures may not represent paleoatmospheric argon. Shungite argon resembles modern atmospheric composition, but constraints on the timing of trapping appear difficult to obtain, as shungites are multicomponent systems. In 40Ar- 39Ar stepwise heating, the isotope fractionation effect could cause systematic underestimations of plateau ages, between 0.15 and 0.4% depending on age, or considerably higher if samples contain appreciable atmospheric Ar. The magnitude of this effect is similar to the presently achieved uncertainties of this increasingly

  9. Effects of nucleotides and nucleosides on coagulation

    DEFF Research Database (Denmark)

    Bune, Laurids; Thaning, Pia; Johansson, Pär I;

    2010-01-01

    Nucleotides, including ADP, ATP and uridine triphosphate (UTP), are discharged profusely in the circulation during many pathological conditions including sepsis. Sepsis can cause hypotension and systemic activation of the coagulation and fibrinolytic systems in humans, which may cause disseminated...... intravascular coagulation. We investigated whether nucleotide-induced cardiovascular collapse as provoked by systemic infusion of adenosine, ADP, ATP, UTP and nitric oxide affected the haemostatic system as assessed by whole blood thromboelastography (TEG) analysis. Ten pigs received a randomized infusion...

  10. Coagulation testing in the perioperative period

    OpenAIRE

    Venkatesan Thiruvenkatarajan; Ashlee Pruett; Sanjib Das Adhikary

    2014-01-01

    Perioperative coagulation management is a complex task that has a significant impact on the perioperative journey of patients. Anaesthesia providers play a critical role in the decision-making on transfusion and/or haemostatic therapy in the surgical setting. Various tests are available in identifying coagulation abnormalities in the perioperative period. While the rapidly available bedside haemoglobin measurements can guide the transfusion of red blood cells, blood product administration is ...

  11. TPEPICO studies near ionization threshold of argon and krypton clusters

    Energy Technology Data Exchange (ETDEWEB)

    Krauss, J.; Vries, J. de; Steger, H.; Kaiser, E.; Kamke, B.; Kamke, W. (Freiburg Univ. (Germany, F.R.). Fakultaet fuer Physik Freiburg Univ. (Germany, F.R.). Freiburger Materialforschungszentrum)

    1991-01-01

    Single photon ionization of argon- and krypton clusters has been studied in the region between threshold and the ionization potential of the corresponding atom. Synchrotron radiation from the electron storage ring BESSY is used to ionize the clusters; threshold-photoelectron-photoion-coincidence (TPEPICO)-time-of-flight technique is used to detect ions correlated with the emission of zero-kinetic-energy-electrons. The spectra of the clusters in the range of n=2 to 15 are discussed in view of the extensive fragmentation taking place in these systems. In order to characterize the properties of the clusters a method using scaling laws is applied. The principles and the deduction of Hagena's scaling parameter {Gamma}{sup *} are briefly reviewed. Using {Gamma}{sup *} an experimentally derived mean cluster size for molecular beams can be assigned. This allows one to clearly demonstrate the systematic variations of the measured spectra due to cluster fragmentation. As a general feature it is observed that, in the range studied, the peak in the measured ionization rate for a cluster ion (fragment) of a given size shifts to higher photon energies as the mean cluster size is increased. (orig.).

  12. High precision wavelength measurements of QED-sensitive forbidden transitions in highly charged argon ions.

    Science.gov (United States)

    Draganić, I; Crespo López-Urrutia, J R; DuBois, R; Fritzsche, S; Shabaev, V M; Orts, R Soria; Tupitsyn, I I; Zou, Y; Ullrich, J

    2003-10-31

    We present the results of an experimental study of magnetic dipole (M1) transitions in highly charged argon ions (Ar X, Ar XI, Ar XIV, Ar XV) in the visible spectral range using an electron beam ion trap. Their wavelengths were determined with, for highly charged ions, unprecedented accuracy up to the sub-ppm level and compared with theoretical calculations. The QED contributions, calculated in this Letter, are found to be 4 orders of magnitude larger than the experimental error and are absolutely indispensable to bring theory and experiment to a good agreement. This method shows great potential for the study of QED effects in relativistic few-electron systems.

  13. R&D Argon Detector at Ash River (RADAR) - Letter of Intent

    CERN Document Server

    Adamson, P; Guzowski, P; Habig, A; Holin, A; Huang, J; Kordosky, M; Kreymer, A E; Lang, K; Marshak, M; Mehdiyev, R; Miller, W H; Naples, D; Nichol, R J; Patterson, R B; Sousa, A; Thomas, J; Whitehead, L H

    2013-01-01

    The RADAR project proposes to deploy a 6 kton liquid argon TPC at the NOvA Far Detector building in Ash River, Minnesota, and expose it to the NuMI beam during NOvA running. It will significantly add to the physics capabilities of the NOvA program while providing LBNE with an R&D program based on full-scale TPC module assemblies. RADAR offers an excellent opportunity to improve the full Homestake LBNE project in physics reach, timeline, costs, and fostering international partnership. The anticipated duration of the project's construction is 5 years, with running happening between 2018 and 2023.

  14. Lithium-argon discharges in a multicusp-ECR microwave resonant cavity

    Energy Technology Data Exchange (ETDEWEB)

    Brooks, C.B.; Brake, M.L. [Univ. of Michigan, Ann Arbor, MI (United States). Dept. of Nuclear Engineering

    1995-12-01

    A newly designed multicusp-ECR microwave resonant cavity is being used as a lithium plasma source. Lithium plasma sources have a variety of applications in nuclear fusion research. As a source of ions or neutrals for beams, they are utilized in diagnostics and fueling of magnetic confinement fusion. Argon and lithium-argon discharges have been created in a multicusp-ECR microwave resonant cavity. A double Langmuir probe has been used to determine discharge characteristics, indicating ion densities of 10{sup 10}--10{sup 11} cm{sup {minus}3} and electron temperatures of about 3 eV with operating pressures of 4--20 mtorr and input powers of 100--250 W. Lithium is introduced to the system in the form of lithium chloride or lithium carbonate which is then heated by a background argon discharge allowing dissociation of lithium. The dissociation is evidenced by the observation of strong Li-I lines in the discharge using optical emission spectroscopy. LiCl was found to give a strong Li-I optical signal for about 15 min run time whereas Li{sub 2}CO{sub 3} gave lower intensity lines, but for about 60 min run time.

  15. The effects of argon ion bombardment on the corrosion resistance of tantalum

    Science.gov (United States)

    Ramezani, A. H.; Sari, A. H.; Shokouhy, A.

    2017-02-01

    Application of ion beam has been widely used as a surface modification method to improve surface properties. This paper investigates the effect of argon ion implantation on surface structure as well as resistance against tantalum corrosion. In this experiment, argon ions with energy of 30 keV and in doses of 1 × 1017-10 × 1017 ions/cm2 were used. The surface bombardment with inert gases mainly produces modified topography and morphology of the surface. Atomic Force Microscopy was also used to patterned the roughness variations prior to and after the implantation phase. Additionally, the corrosion investigation apparatus wear was applied to compare resistance against tantalum corrosion both before and after ion implantation. The results show that argon ion implantation has a substantial impact on increasing resistance against tantalum corrosion. After the corrosion test, scanning electron microscopy (SEM) analyzed the samples' surface morphologies. In addition, the elemental composition is characterized by energy-dispersive X-ray (EDX) analysis. The purpose of this paper was to obtain the perfect condition for the formation of tantalum corrosion resistance. In order to evaluate the effect of the ion implantation on the corrosion behavior, potentiodynamic tests were performed. The results show that the corrosion resistance of the samples strongly depends on the implantation doses.

  16. Angle dependence of argon gas cluster sputtering yields for organic materials.

    Science.gov (United States)

    Seah, M P; Spencer, S J; Shard, A G

    2015-02-19

    The first angle-dependent measurements of the sputtering yield of an organic material using argon gas cluster ions under a wide range of conditions are reported in order to develop an analytical description of the behavior important for the development of the application of secondary ion mass spectrometry to organic and biological systems. Data are presented for Irganox 1010 using argon gas cluster ion beams of 5 and 10 keV energy, E, with cluster sizes, n, from 1000 to 5000. The measurements are conducted in an X-ray photoelectron spectrometer for a range of angles from 0 to 80° from the surface normal. The results support the Universal Equation for argon gas cluster sputtering yields with the angle dependence incorporated into the equation via a simple angle dependence of the parameter A. This explains how and why the angular dependence of the sputtering yield changes significantly with increasing E/n. These results are also accurately confirmed using the published measurements for polystyrene by Rading et al.

  17. Measurement of neutrino interactions in gaseous argon with T2K

    CERN Document Server

    ,

    2016-01-01

    The T2K near-detector, ND280, employs three large argon gas TPCs (Time Projection Chambers) for particle tracking and identification. The gas inside the TPCs can be used as an active target to study the neutrino interactions in great detail. The low density of the gas leads to very low track energy thresholds, allowing the reconstruction of very low momentum tracks, e.g. protons with kinetic energies down to $\\mathcal{O}$(1 MeV). Since different nuclear interaction models vary considerably in their predictions of those low momentum track multiplicities, this makes neutrino interactions on gases a powerful probe to test those models. The TPCs operate with an argon-based gas mixture (95% by volume) and have been exposed to the T2K neutrino beam since the beginning of the experiment in 2010. Due to the low total mass of the gas, neutrino argon interactions happen only rarely, compared to the surrounding scintillator-based detectors. We expect about 600 such events in the recorded data so far (about 200 in the fi...

  18. [Incidental finding of pathological coagulation parameters].

    Science.gov (United States)

    Luxembourg, B; Lindhoff-Last, E

    2014-10-01

    Pathological coagulation parameters may reflect life-threatening hemorrhagic or thromboembolic diseases but may also be a laboratory result without any clinical significance, result from in vitro phenomena or preanalytical errors. This article gives an overview of potential pitfalls in coagulation diagnostics, lists the differential diagnoses of pathological coagulation parameters and describes further steps in the diagnostic approach to clarify pathological results. The focus lies on coagulation parameters that are frequently determined in routine clinical investigations, e.g. platelet count, prothrombin time, activated partial thromboplastin time (aPTT) and fibrinogen. Besides heparin, fondaparinux, danaparoid, and vitamin K antagonists, direct factor Xa inhibitors and direct thrombin inhibitors are nowadays available for therapeutic anticoagulation. This article gives an overview of the influence of anticoagulants on coagulation parameters which depends on the dose, the time of the last administration, as well as the method used for the determination of coagulation parameters. Moreover, common reasons for elevation of the fibrin degradation product D-dimer are presented. The clinical utility of D-dimer assays is limited by their poor specificity. Elevated D-dimer concentrations can be found in various diseases and also under normal physiological circumstances (e.g. in the elderly). Thus, the most useful clinical application of D-dimer is evidence of normal values to essentially rule out venous thromboembolism.

  19. Optical readout of liquid argon ionisation

    Science.gov (United States)

    Spooner, N. J. C.; Lightfoot, P. K.; Barker, G. J.; Ramachers, Y. A.; Mavrokoridis, K.

    2011-07-01

    Reading out the charge from a very large liquid argon detector, such as proposed for next generation proton decay and long baseline neutrino detectors, represents a significant challenge. Current proposals suggest using wires in the liquid or a two-phase approach that can provide some gain via amplification in the gas phase. We present here work on an alternative new approach in which the charge is read out by optical means following generation of electroluminescence, such as in a THGEM (Thick Gas Electron Multiplier) mounted within the liquid. This has the potential for significant advantages by providing both simpler readout electronics and significant charge gain, without the need for the complexities of dual phase operation. Tests with a silicon photomultiplier (SiPM) mounted above a THGEM, all submerged in liquid argon, have allowed first demonstration of the technique. Sensitivity to 5.9 keV 55Fe gamma events was observed with an estimated gain of 150 photoelectrons per drifted electron. We review the concepts and results.

  20. Performance of a liquid argon accordion hadronic calorimeter prototype

    Energy Technology Data Exchange (ETDEWEB)

    Gingrich, D.M. [Alberta Univ., Edmonton, AB (Canada); Greeniaus, G. [Alberta Univ., Edmonton, AB (Canada); Kitching, P. [Alberta Univ., Edmonton, AB (Canada); Olsen, B. [Alberta Univ., Edmonton, AB (Canada); Pinfold, J.L. [Alberta Univ., Edmonton, AB (Canada); Rodning, N.L. [Alberta Univ., Edmonton, AB (Canada); Boos, E. [Alma-Ata (Kazakhstan); Schaoutnikov, B.O. [Alma-Ata (Kazakhstan); Aubert, B. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Bazan, A. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Beaugiraud, B. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Boniface, J. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Colas, J. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Jezequel, S. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Leflour, T. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Maire, M. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Rival, F. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Stipcevic, M. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Thion, J. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; VanDenPlas, D. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Wingerter-Seez, I. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Zolnierowski, Y.P. [Grenoble-1 Univ., 74 - Annecy (France). Lab. de Physique des Particules; Chmeissani, M. [Universidad Autonoma de Barcelona (Spain); Fernandez, E. [Universidad Autonoma de Barcelona (Spain); Garrido, L. [Universidad Autonoma de Barcelona (Spain); Martinez, M. [Universidad Autonoma de Barcelona (Spain); Padilla, C. [Universidad Autonoma de Barcelona (Spain); Gordon, H.A. [Brookhaven National Lab., Upton, NY (United States); RD3 Colla...

    1995-02-15

    A liquid argon hadronic calorimeter using the ``accordion`` geometry and the electrostatic transformer readout scheme has been tested at CERN, together with a liquid argon accordion electromagnetic prototype. The results obtained for pions on the linearity, the energy resolution and the uniformity of the calorimeter response are well within the requirements for operation at the LHC. ((orig.))

  1. Comparison of Diode and Argon Laser Lesions in Rabbit Retina

    Institute of Scientific and Technical Information of China (English)

    Hui Zhang; Xiaoxin Li; Bin Li; Jiping Da

    2004-01-01

    Purpose: To compare the histological alteration of retina with various spot intensities between diode and argon lasers in order to instruct the clinical use of 810 nm diode laser.Methods: Transpupillary retinal photocoagulations were performed on 42 eyes of 27pigmented rabbits. Histopathologic alteration of lesions in different intensities and different time intervals after irradiation produced by diode and argon laser was observed and compared using light microscopy. Areas of various lesions measured by image analysis system (CMIAS) were compared quantitatively.Results: Histopathologically, two-week-old grade 2 lesions produced by diode laser induced the disappearance of outer nuclear cells. More than a half of all showed reduction in number of outer nuclear layer cells in argon. Fibroblasts appeared in the diode grade 3lesions 5 days after irradiation. CMIAS data showed that all the areas of diode lesions immediately after photocoagulation were to be larger than those of argon laser lesions in the same spot intensity (P < 0.05). However, twenty-four hours after photocoagulation, the area of the diode lesions increased less than that of the argon laser lesions (8%vs.23%).Conclusion: The acute histological effect caused by 810 nm diode laser and argon green laser is similar,while the expansion of lesion area 24 hours after photocoagulation was less with the diode laser compared to the argon. This may be the first report in the literature regarding quantitative analysis of the delayed reaction of argon green lasers.

  2. Stopping Power of Solid Argon for Helium Ions

    DEFF Research Database (Denmark)

    Besenbacher, F.; Bøttiger, Jørgen; Grauersen, O.

    1981-01-01

    By means of the Rutherford-backscattering method, the stopping cross section of solid argon has been measured for 0.5–3 MeV helium ions to an accuracy of not, vert, similar3%. The results agree within the experimental accuracies with our earlier measurements for gaseous argon over the energy region...

  3. Improved installation prototype for measurement of low argon-37 activity

    Science.gov (United States)

    Pakhomov, Sergei; Dubasov, Yuri

    2015-04-01

    On-site Inspection (OSI) is a key element of verification of State Parties' compliance with the Comprehensive Nuclear-Test-Ban Treaty (CTBT). An on-site inspection is launched to establish whether or not a nuclear explosion has been carried out. One of the most significant evidence of n underground nuclear explosion (UNE) is detection above background concentrations of argon-37 in near surface air. Argon-37 is formed in large amounts at interaction of neutrons of UNE with the potassium which is a part of the majority of rocks. Its estimated contents for the 100th days after explosion with a energy of 1000 t of TNT near a surface can vary from 1 to 1000 mBq/m3. The background concentrations of argon-37 in subsoil air vary 1 do100 mBq/m3. Traditionally, for argon-37 activity measurement the gas-proportional counters are used. But at Khlopin Radium institute the developments of the new type of highly sensitive and low-background installation capable to provide the required range of measurements of the argon-37 concentration are conducted. The liquid scintillation method of the registration of the low-energetic argon-37 electrons is the basic installation principle and as scintillator, the itself condensed air argon sample is used. Registration of scintillations of liquid argon is made by means of system from 3 PMT which cathodes are cooled near to the temperature of liquid nitrogen together with the measuring chamber in which placed the quartz glass ampule, containing the measured sample of the liquefied argon. For converse the short wavelength photons (λ = 127 nm) of liquid argon scintillations to more long-wave, corresponding to the range of PMT sensitivity, the polymer film with tetra-phenyl-butadiene (TPB) is provided. Even the insignificant impurities of nitrogen, oxygen and others gaseous in the liquid argon samples can to cause the quenching of scintillation, especially their slow components. To account this effect and it influence on change of registration

  4. Argon Diffusion Measured in Rhyolite Melt at 100 MPa

    Science.gov (United States)

    Weldon, N.; Edwards, P. M.; Watkins, J. M.; Lesher, C. E.

    2016-12-01

    Argon diffusivity (D_{Ar} ) controls the rate and length scale of argon exchange between melt and gas phases and is used as a parameter to model noble gas fractionation during magma degassing. D_{Ar} may also be useful in geochronology to estimate the distribution of excess (non-radiogenic) atmospheric argon in lavas. Our measurements of D_{Ar} in molten anhydrous rhyolite near 1000 °C and 100 MPa add to the existing dataset. Using a rapid-quench cold seal pressure apparatus we exposed cylindrical charges drilled from a Miocene rhyolite flow near Buck Mtn., CA to a pure argon atmosphere resulting in a gradually lengthening argon concentration gradient between the saturated surface and the argon poor interior. Argon concentration was measured by electron microprobe along radial transects from the center to the surface of bisected samples. D_{Ar} was calculated for each transect by fitting relative argon concentration (as a function of distance from the surface) to Green's function (given each experiment's specific temperature, pressure and runtime). Variability (σ = 1.202{μm }^{2} /s) was smaller than in previous studies, but still greater than what is likely due to analytical or experimental uncertainty. We observed a symmetric geometric bias in the distribution of argon in our samples, possibly related to advective redistribution of argon accompanying the deformation of cylindrical charges into spheroids driven by surface tension. Average diffusivity, D_{Ar} = 4.791{μm }^{2} /s, is close to the predicted value, D_{Ar} = {μm }^{2} /s ( σ_{ \\bar{x} } = 1.576 {μm }^{2} /s), suggesting that Behrens and Zhang's (2001) empirical model is valid for anhydrous rhyolite melts to relatively higher temperatures and lower pressures. Behrens, H. and Y. Zhang (2001). "Ar diffusion in hydrous silicic melts: implications for volatile diffusion mechanisms and fractionation." Earth and Planetary Science Letters 192: 363-376.

  5. Diagnosis and treatment of disseminated intravascular coagulation.

    Science.gov (United States)

    Levi, M

    2014-06-01

    Disseminated intravascular coagulation (DIC) is a condition in which systemic activation of coagulation without a specific localization occurs, resulting in extensive formation of intravascular fibrin, particularly in small and midsize vessels. Disseminated intravascular coagulation may lead to several altered coagulation parameters, including a low platelet count, abnormal global clotting assays, low levels of physiological anticoagulant proteases, or increased fibrin degradation products. Also, more complex assays for activation of coagulation factors or pathways may indicate involvement of these molecules in DIC. None of these tests alone, however, can accurately ascertain or rebuff a diagnosis of DIC. Nonetheless, a combination of readily available routine assays may be instrumental in establishing a diagnosis of DIC and can also be useful to point to a subset of patients with DIC that may need definite, often costly, interventions in the hemostatic system. Current insights on relevant etiological pathways that may contribute to the occurrence of DIC have led to innovative therapeutic and adjunctive approaches to patient with DIC. Management options directed at the amelioration of hemostatic activation may tentatively be indicated and were found to be advantageous in experimental and clinical investigations. These treatments encompass elimination of tissue factor-mediated thrombin generation or restitution of normal anticoagulant function.

  6. Magnetic particle imaging of blood coagulation

    Energy Technology Data Exchange (ETDEWEB)

    Murase, Kenya, E-mail: murase@sahs.med.osaka-u.ac.jp; Song, Ruixiao; Hiratsuka, Samu [Department of Medical Physics and Engineering, Division of Medical Technology and Science, Faculty of Health Science, Graduate School of Medicine, Osaka University, Osaka 565-0871 (Japan)

    2014-06-23

    We investigated the feasibility of visualizing blood coagulation using a system for magnetic particle imaging (MPI). A magnetic field-free line is generated using two opposing neodymium magnets and transverse images are reconstructed from the third-harmonic signals received by a gradiometer coil, using the maximum likelihood-expectation maximization algorithm. Our MPI system was used to image the blood coagulation induced by adding CaCl{sub 2} to whole sheep blood mixed with magnetic nanoparticles (MNPs). The “MPI value” was defined as the pixel value of the transverse image reconstructed from the third-harmonic signals. MPI values were significantly smaller for coagulated blood samples than those without coagulation. We confirmed the rationale of these results by calculating the third-harmonic signals for the measured viscosities of samples, with an assumption that the magnetization and particle size distribution of MNPs obey the Langevin equation and log-normal distribution, respectively. We concluded that MPI can be useful for visualizing blood coagulation.

  7. Viscoelastic coagulation testing: technology, applications, and limitations.

    Science.gov (United States)

    McMichael, Maureen A; Smith, Stephanie A

    2011-06-01

    Use of viscoelastic point-of-care (POC) coagulation instrumentation is relatively new to veterinary medicine. In human medicine, this technology has recently undergone resurgence owing to its capacity to detect hypercoagulability. The lack of sensitive tests for detecting hypercoagulable states, along with our current understanding of in vivo coagulation, highlights the deficiencies of standard coagulation tests, such as prothrombin and partial thromboplastin times, which are performed on platelet-poor plasma. Viscoelastic coagulation analyzers can provide an assessment of global coagulation, from the beginning of clot formation to fibrinolysis, utilizing whole blood. In people, use of this technology has been reported to improve management of hemostasis during surgery and decrease usage of blood products and is being used as a rapid screen for hypercoagulability. In veterinary medicine, clinical use of viscoelastic technology has been reported in dogs, cats, foals, and adult horses. This article will provide an overview of the technology, reagents and assays, applications in human and veterinary medicine, and limitations of the 3 viscoelastic POC analyzers in clinical use.

  8. Magnetic particle imaging of blood coagulation

    Science.gov (United States)

    Murase, Kenya; Song, Ruixiao; Hiratsuka, Samu

    2014-06-01

    We investigated the feasibility of visualizing blood coagulation using a system for magnetic particle imaging (MPI). A magnetic field-free line is generated using two opposing neodymium magnets and transverse images are reconstructed from the third-harmonic signals received by a gradiometer coil, using the maximum likelihood-expectation maximization algorithm. Our MPI system was used to image the blood coagulation induced by adding CaCl2 to whole sheep blood mixed with magnetic nanoparticles (MNPs). The "MPI value" was defined as the pixel value of the transverse image reconstructed from the third-harmonic signals. MPI values were significantly smaller for coagulated blood samples than those without coagulation. We confirmed the rationale of these results by calculating the third-harmonic signals for the measured viscosities of samples, with an assumption that the magnetization and particle size distribution of MNPs obey the Langevin equation and log-normal distribution, respectively. We concluded that MPI can be useful for visualizing blood coagulation.

  9. Coagulation management in patients undergoing neurosurgical procedures.

    Science.gov (United States)

    Robba, Chiara; Bertuetti, Rita; Rasulo, Frank; Bertuccio, Alessando; Matta, Basil

    2017-10-01

    Management of coagulation in neurosurgical procedures is challenging. In this contest, it is imperative to avoid further intracranial bleeding. Perioperative bleeding can be associated with a number of factors, including anticoagulant drugs and coagulation status but is also linked to the characteristic and the site of the intracranial disorder. The aim of this review will be to focus primarily on the new evidence regarding the management of coagulation in patients undergoing craniotomy for neurosurgical procedures. Antihemostatic and anticoagulant drugs have shown to be associated with perioperative bleeding. On the other hand, an increased risk of venous thromboembolism and hypercoagulative state after elective and emergency neurosurgery, in particular after brain tumor surgery, has been described in several patients. To balance the risk between thrombosis and bleeding, it is important to be familiar with the perioperative changes in coagulation and with the recent management guidelines for anticoagulated patients undergoing neurosurgical procedures, in particular for those taking new direct anticoagulants. We have considered the current clinical trials and literature regarding both safety and efficacy of deep venous thrombosis prophylaxis in the neurosurgical population. These were mainly trials concerning both elective surgical and intensive care patients with a poor grade intracranial bleed or multiple traumas with an associated severe traumatic brain injury (TBI). Coagulation management remains a major issue in patients undergoing neurosurgical procedures. However, in this field of research, literature quality is poor and further studies are necessary to identify the best strategies to minimize risks in this group of patients.

  10. Injection of photoelectrons into dense argon gas

    CERN Document Server

    Borghesani, A F

    2010-01-01

    The injection of photoelectrons in a gaseous or liquid sample is a widespread technique to produce a cold plasma in a weakly--ionized system in order to study the transport properties of electrons in a dense gas or liquid. We report here the experimental results of photoelectron injection into dense argon gas at the temperatureT=142.6 K as a function of the externally applied electric field and gas density. We show that the experimental data can be interpreted in terms of the so called Young-Bradbury model only if multiple scattering effects due to the dense environment are taken into account when computing the scattering properties and the energetics of the electrons.

  11. Commissioning of the ATLAS liquid argon calorimeters

    CERN Document Server

    Rezaie, Erfan

    ATLAS, a multi-purpose detector built at the LHC at CERN, requires an extensive commissioning campaign to be ready for proton-proton collisions. In this work, we focus on the commissioning of the liquid Argon (LAr) calorimeters, with emphasis on commissioning with cosmic rays. First we outline one phase of the commissioning work, which involves testing of the front-end electronics of the two endcap calorimeters. We then describe two cosmic ray generators as input to a Monte-Carlo simulation of cosmic rays in ATLAS, and compare their results. Finally, we explain a technique developed for this work which uses information from the Tile calorimeters to predict the timing of cosmic rays within the LAr calorimeters, because cosmic rays occur randomly in time whereas the electronics are clocked at [Special characters omitted.] . The results from this analysis tool are compared to default tools, using both simulated and real cosmic ray data in the calorimeters.

  12. Merging of high speed argon plasma jets

    Energy Technology Data Exchange (ETDEWEB)

    Case, A.; Messer, S.; Brockington, S.; Wu, L.; Witherspoon, F. D. [HyperV Technologies Corp., Chantilly, Virginia 22180 (United States); Elton, R. [University of Maryland, College Park, Maryland 20742 (United States)

    2013-01-15

    Formation of an imploding plasma liner for the plasma liner experiment (PLX) requires individual plasma jets to merge into a quasi-spherical shell of plasma converging on the origin. Understanding dynamics of the merging process requires knowledge of the plasma phenomena involved. We present results from the study of the merging of three plasma jets in three dimensional geometry. The experiments were performed using HyperV Technologies Corp. 1 cm Minirailguns with a preionized argon plasma armature. The vacuum chamber partially reproduces the port geometry of the PLX chamber. Diagnostics include fast imaging, spectroscopy, interferometry, fast pressure probes, B-dot probes, and high speed spatially resolved photodiodes, permitting measurements of plasma density, temperature, velocity, stagnation pressure, magnetic field, and density gradients. These experimental results are compared with simulation results from the LSP 3D hybrid PIC code.

  13. ArgonCube: a Modular Approach for Liquid Argon TPC Neutrino Detectors for Near Detector Environments

    CERN Document Server

    Auger, M; Sinclair, JR

    2017-01-01

    Liquid Argon Time Projection Chambers (LAr TPCs) are an ideal detector candidate for future neutrino oscillation physics experiments, underground neutrino observatories and proton decay searches. A large international project based on this technology is currently under consideration at the future LBNF/DUNE facility in the United States. That particular endeavor would be on the very large mass scale of 40~kt. Following diverse and long standing R\\&D work conducted over several years, with contributions from international collaborators, we propose a novel LAr TPC based on a fully-modular, innovative design, ArgonCube. ArgonCube will demonstrate that LAr TPCs are a viable detector technology for high-energy and high-multiplicity environments, such as the DUNE near detector. Necessary R\\&D work is proceeding along two main pathways; the first, aimed at the demonstration of modular detector design and the second, at the exploration of new signal readout methods. This two-pronged approach has provided a hig...

  14. Study of Neutron-Induced Ionization in Helium and Argon Chamber Gases

    CERN Document Server

    Indurthy, D; Harris, D; Kopp, S; Proga, M; Zwaska, R M

    2004-01-01

    Ion chambers used to monitor the secondary hadron and tertiary muon beam in the NuMI neutrino beamline will be exposed to background particles, including low energy neutrons produced in the beam dump. To understand these backgrounds, we have studied Helium- and Argon-filled ionization chambers exposed to intense neutron fluxes from PuBe neutron sources ($E_n=1-10$ MeV). The sources emit about 10$^8$ neutrons per second. The number of ion pairs in the chamber gas volume per incident neutron is derived. While limited in precision because of a large gamma ray background from the PuBe sources, our results are consistent with the expectation that the neutrons interact purely elastically in the chamber gas.

  15. Coagulation of carbon clusters in detonation front

    Science.gov (United States)

    Kupershtokh, A. L.; Ershov, A. P.; Medvedev, D. A.

    1996-05-01

    During the detonation synthesis, diamonds of ˜3 nm in size are produced from the excess carbon released in explosion. Coagulation occurs generally well below the melting temperature. Molecular dynamic simulations within the framework of simple Lennard-Jones model showed important features of interacting carbon clusters: 1) Coagulation is exothermic, and small clusters merge as liquid drops. Clusters larger than ˜3 nm unite keeping their shape, but surface atoms are in quasimolten state and can migrate between two grains. This "wetting" is rather slow. For small clusters there exist considerable temperature fluctuations due to interaction with the thermal bath. 2) Coagulation is accompanied by strong tensions. Both positive and negative pressure phases during the collision can reach ˜30 GPa. This can explain why the region of good diamond yield lies on P-T plane much higher than the graphite-diamond transition line.

  16. Monitoring Thermal Coagulation with Ultrasonic Textures

    Institute of Scientific and Technical Information of China (English)

    YANG Wei; ZHANG Su; CHEN Ya-zhu; CHEN Lei; HU Bing; MA Wei-yin

    2007-01-01

    The feasibility of using B-mode ultrasound image textures and pattern recognition technique to characterize the thermal coagulation in vitro during radiofrequency ablation was investigated.The changes of ultrasonic textures in the different regions of samples varied with the heating time in the in-vitro experiments, which would result in that the coagulated and noncoagulated regions of tissue had different ultrasonic textures.Using support vector machine to extract the ultrasonic texture features and characterize the state of tissue, the size and boundaries of thermal lesions could be detected and measured more exactly than only using the gray scale information of B-mode ultrasound image.The proposed method would be applied to the image-guided radiofrequency ablation (IGRA) procedure for monitoring the thermal coagulation.

  17. Coagulation function in patients with pancreatic carcinoma

    Institute of Scientific and Technical Information of China (English)

    WANG Hang-yan; XIU Dian-rong; LI Zhi-fei; WANG Gang

    2009-01-01

    Background The coagulation function in patients with pancreatic carcinoma is abnormal and the reason is not very clear. In this study, we retrospectively analyzed the coagulation function in patients with pancreatic carcinoma.Methods From June 2004 to December 2007, 132 patients received diagnosis and treatment in our hospital. The coagulative parameters including the prothrombin time, activated partial thromboplastin time, and fibrinogen levels were collected and studied retrospectively.Results The average fibrinogen levels in patients with pancreatic carcinoma, (476.21±142.05) mg/dl, were significantly higher than in patients with cholangiolithiasis, (403.28±126.41) mg/dl (P 0.05).Conclusions The level of fibrinogen in patients with pancreatic carcinoma was elevated. The elevated fibrinogen level may be associated with invasiveness and lymphatic metastasis. Using vitamin K in perioperation management did not reduce intraoperative blood loss.

  18. Cutting and coagulation during intraoral soft tissue surgery using Er: YAG laser.

    Science.gov (United States)

    Onisor, I; Pecie, R; Chaskelis, I; Krejci, I

    2013-06-01

    To find the optimal techniques and parameters that enables Er:YAG laser to be used successfully for small intraoral soft tissue interventions, in respect to its cutting and coagulation abilities. In vitro pre-tests: 4 different Er:YAG laser units and one CO2 unit as the control were used for incision and coagulation on porcine lower jaws and optimal parameters were established for each type of intervention and each laser unit: energy, frequency, type, pulse duration and distance. 3 different types of intervention using Er:YAG units are presented: crown lengthening, gingivoplasty and maxillary labial frenectomy with parameters found in the in vitro pre-tests. The results showed a great decrease of the EMG activity of masseter and anterior temporalis muscles. Moreover, the height and width of the chewing cycles in the frontal plane increased after therapy. Er:YAG is able to provide good cutting and coagulation effects on soft tissues. Specific parameters have to be defined for each laser unit in order to obtain the desired effect. Reduced or absent water spray, defocused light beam, local anaesthesia and the most effective use of long pulses are methods to obtain optimal coagulation and bleeding control.

  19. The investigation of coagulation activity of natural coagulants extracted from different strains of common bean

    Directory of Open Access Journals (Sweden)

    Šćiban Marina B.

    2010-01-01

    Full Text Available Coagulation and flocculation by adding chemicals are the methods that are usually used for removal of water turbidity. This study is concerned with the coagulation activity of extracts of various strains of bean. The aim was to ascertain if bean varieties influence coagulation activity. Active components were extracted from 1 g of ground sample with 100 ml distilled water. Contents of dry matter and nitrogen were specified in the solid samples, and the content of soluble nitrogen was determined in the extracts. These data were used to calculate the efficiency of extraction of nitrogen-containing compounds. The coagulation activity was assessed by jar test using synthetic turbid water, of the initial pH 9 and turbidity 35 NTU. The jar test was carried out by adding different amounts of extracts to model water, and stirring the content. After sedimentation for 1 h, residual turbidity was determined by turbidimeter and coagulation activity was calculated. The increment of organic matter concentration after the coagulation was also determined. These experiments confirmed that extracts of all investigated strains of bean could be used successfully as natural coagulants.

  20. Disseminated intravascular coagulation in burn injury.

    Science.gov (United States)

    Lippi, Giuseppe; Ippolito, Luigi; Cervellin, Gianfranco

    2010-06-01

    Disseminated intravascular coagulation (DIC) is a complex and multifaceted disorder characterized by the activation of coagulation and fibrinolytic pathways, consumption of coagulation factors, and depletion of coagulation regulatory proteins. The introduction into the circulation of cellular debris characterized by strong thromboplastic activity due to tissue factor exposition or release (in or from burned tissues), which can thereby activate extrinsic pathway of coagulation system and trigger massive thrombin generation when present in sufficient concentration, represents the most plausible biological explanation to support the development of intravascular coagulation in patients with burn injury. Severe burns left untreated might also lead to an immunological and inflammatory response (activation of the complement cascade), which can amplify fibrinolysis and blood clotting. Overall, the real prevalence of DIC in patients with burns is as yet unclear. Postmortem, retrospective, and even longitudinal investigations are in fact biased by several factors, such as the objective difficulty to establish whether DIC might have occurred as a primary complication of burns or rather as a consequence of other superimposed pathologies (e.g., sepsis, multiple organ failure), the different diagnostic criteria for assessing DIC, and the heterogeneity of the patient samples studied. Nevertheless, the current scientific evidence is consistent with the hypothesis that biochemical changes suggestive for DIC (hypercoagulability, hypo- and hyperfibrinolysis) are commonplace in patients with burn trauma, and their severity increases exponentially with the severity of injury. Overt DIC seems to occur especially in critically ill burn patients or in those with severe burns (up to third degree) and large involvement of body surface area, in whom an appropriate therapy might be effective to prevent the otherwise fulminant course. Although early prophylaxis with antithrombin concentrates

  1. Argon laser induced changes to the carbonate content of enamel

    Energy Technology Data Exchange (ETDEWEB)

    Ziglo, M.J. [Orthodontic Graduate Program, Faculty of Medicine and Dentistry, University of Alberta, Private Practice, Regina, Saskatchewan (Canada); Nelson, A.E., E-mail: aenelson@dow.com [Department of Chemical and Materials Engineering, Faculty of Engineering, University of Alberta (Canada); Heo, G.; Major, P.W. [Orthodontic Graduate Program, Faculty of Medicine and Dentistry, University of Alberta (Canada)

    2009-05-15

    Argon laser irradiation can be used to cure orthodontic brackets onto teeth in significantly less time than conventional curing lights. In addition, it has been shown that the argon laser seems to impart a demineralization resistance to the enamel. The purpose of this study was to use surface science techniques to ascertain if this demineralization resistance is possibly a result of a decrease in the carbonate content of enamel. Eleven mandibular third molars previously scheduled for extraction were collected and used in the present study. The teeth were sectioned in two and randomly assigned to either the argon laser (457-502 nm; 250 mW cm{sup -2}) or the control (no treatment) group. The sections assigned to the argon laser group were cured for 10 s and analyzed. To exaggerate any potential changes the experimental sections were then exposed to a further 110 s of argon laser irradiation. Surface analysis was performed using X-ray photoelectron spectroscopy (XPS) and time-of-flight secondary ion mass spectrometry (ToF-SIMS). The results showed no statistically significant change in the carbonate content of enamel after argon laser irradiation (p > 0.05). Thus, it is suggested that any demineralization resistance imparted to the enamel surface by argon laser irradiation is not due to alterations in carbonate content.

  2. Effects of nucleotides and nucleosides on coagulation

    DEFF Research Database (Denmark)

    Bune, Laurids; Thaning, Pia; Johansson, Pär I;

    2010-01-01

    intravascular coagulation. We investigated whether nucleotide-induced cardiovascular collapse as provoked by systemic infusion of adenosine, ADP, ATP, UTP and nitric oxide affected the haemostatic system as assessed by whole blood thromboelastography (TEG) analysis. Ten pigs received a randomized infusion......Nucleotides, including ADP, ATP and uridine triphosphate (UTP), are discharged profusely in the circulation during many pathological conditions including sepsis. Sepsis can cause hypotension and systemic activation of the coagulation and fibrinolytic systems in humans, which may cause disseminated.......7 ng/ml; P blood was evaluated by TEG. Circulating ADP induces hypocoagulation without signs of increased fibrinolysis as evaluated by TEG. The potential...

  3. Effect of rivaroxaban on blood coagulation using the viscoelastic coagulation test ROTEM™.

    Science.gov (United States)

    Casutt, M; Konrad, C; Schuepfer, G

    2012-11-01

    This study investigated the influence of the oral direct inhibitor of factor Xa rivaroxaban on blood coagulation measured by rotation thrombelastometry ROTEM™. Blood was obtained from 11 healthy male volunteers before and 2.5 h after oral administration of 10 mg rivaroxaban. In addition to standard coagulation tests clot formation was measured by ROTEM™ analyzing extrinsic (Extem) and intrinsic thrombelastometry (Intem). Significant differences to the baseline values were found in the Extem clotting time (Extem-CT, 58 ± 9 s and 87 ± 17 s, p coagulation by rivaroxaban.

  4. Modeling Electronegative Impurity Concentrations in Liquid Argon Detectors

    Science.gov (United States)

    Tang, Wei; Li, Yichen; Thorn, Craig; Qian, Xin

    2017-01-01

    Achieving long electron lifetime is crucial to reach the high performance of large Liquid Argon Time Projection Chamber (LArTPC) envisioned for next generation neutrino experiments. We have built up a quantitative model to describe the impurity distribution and transportation in a cryostat. Henrys constants of Oxygen and water, which describe the partition of impurities between gas argon and liquid argon, have been deduced through this model with the measurements in BNL 20-L LAr test stand. These results indicate the importance of the gas purification system and prospects on large LArTPC detectors will be discussed.

  5. Practical reactor production of {sup 41}Ar from argon clathrate

    Energy Technology Data Exchange (ETDEWEB)

    Mercer, J.R. E-mail: jmercer@pharmacy.ualberta.ca; Duke, M.J.M.; McQuarrie, S.A

    2000-06-01

    The radionuclide {sup 41}Ar has many ideal properties as a gas flow tracer. However, the modest cross-section of {sup 40}Ar for thermal neutron activation makes preparation of suitable activities of {sup 41}Ar technically difficult particularly for low flux reactors. Argon can however be trapped in a molecular complex called a clathrate that can then be irradiated. We prepared argon clathrate and explored its irradiation and stability characteristics. Argon clathrate can be used to provide gigabecquerel quantities of {sup 41}Ar even with low power reactors.

  6. Analysis of tungsten carbide coatings by infrared laser-induced argon spark with inductively coupled plasma atomic emission spectrometry

    Science.gov (United States)

    Kanický, V.; Otruba, V.; Mermet, J.-M.

    2000-10-01

    Infrared laser ablation was studied for application to the analysis of plasma-sprayed tungsten carbide/cobalt coatings. The potential of the laser induced argon-spark (LINA-Spark™), as a sample introduction device in inductively coupled plasma atomic emission spectrometry was studied. The use of an IR laser along with defocusing led to laser-induced microplasma-based ablation. The mass ablation rate, represented by the ICP emission intensity per laser beam unit area, exhibited a flat increase in the irradiance range 2-250 GW/cm 2. A low slope (0.5) of this dependence in log-log scale gave evidence of plasma shielding. The steep increase in the measured acoustic signal when focused in front of the sample, i.e. in argon, indicated a breakdown of argon. Consequently, considerably lower ICP emissions were observed within the same range of irradiance. The cobalt/tungsten line intensity ratio in the ICP was practically constant from 1.5 up to at least 250 GW/cm 2. Acceptable precision (R.S.D.<5%) was obtained without internal standardization for irradiance between 2 and 8 GW/cm 2. Optimization of the laser pulse energy, repetition rate, beam focusing and sample displacement during interaction led to the linearization of dependences of signal vs. cobalt percentage, at least up to the highest studied value of 23% Co.

  7. [The implantation of bipolar coagulation to remove endometriosis foci].

    Science.gov (United States)

    Sobkiewicz, S; Palatyński, A; Salata, I

    2001-05-01

    The paper compares the results of bipolar coagulation bey means of ERBE ICC 300 diatermy coagulator and WISAP endocoagulator. The results of both types of coagulation were assessed with reference to the changes occurring on peritoneum ligamenti sacro-uterini, Douglas pouch and ovary. The best results of endometriosis foci coagulation were obtained with bipolar ball at 20-30 W; no side effects or feelings of malaise were observed in patients just after the operation or over a longer period of convalescence.

  8. Mathematical Model of Extrinsic Blood Coagulation Cascade Dynamic System

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The blood coagulation system is very important to life. This paper presents a mathematical blood coagulation model for the extrinsic pathway. This model simulates clotting factor VIII, which plays an important role in the coagulation mechanism. The mathematical model is used to study the equilibrium stability, orbit structure, attractors and global stability behavior, with conclusions in accordance with the physiological phenomena. Moreover, the results provide information about blood related illnesses, which can be used for further study of the coagulation mechanism.

  9. The relationship between inflammation and the coagulation system

    NARCIS (Netherlands)

    Choi, Goda; Schultz, Marcus J; Levi, Marcel; van der Poll, Tom

    2006-01-01

    Inflammation and coagulation play pivotal roles in host defence. As phylogenetically old responses, there is extensive cross-talk between inflammation and coagulation in enabling an adequate immune response against potentially injurious stimuli. Immune cells are important in the initiation of coagul

  10. Diagnosis of overt disseminated intravascular coagulation in critically Ill adults by Sonoclot coagulation analysis.

    Science.gov (United States)

    Wan, Peng; Tong, Hua-Sheng; Zhang, Xing-Qin; Duan, Peng-Kai; Tang, You-Qing; Su, Lei

    2014-08-01

    Disseminated intravascular coagulation (DIC) diagnosis is hampered by the limited availability of reliable clinical or laboratory tests. Currently available tests are time consuming and expensive. We investigated whether coagulation and platelet function analyses using the Sonoclot system were suitable for overt DIC diagnosis in critically ill adults. This was an observational diagnostic study performed in 498 patients presenting with an underlying disorder associated with DIC. Overt DIC patients were identified according to an International Society on Thrombosis and Hemostasis (ISTH) score of >5. Coagulation and platelet parameters were analyzed using the Sonoclot system, and compared with ISTH as the gold standard. Receiver operating characteristic curves and area under the curves were used to evaluate the value of the Sonoclot parameters. There were no differences for age or gender between the groups. Significant correlations were observed between activated clotting time (ACT) and ISTH score (r = 0.7; P coagulation dysfunction in patients with overt DIC.

  11. Laboratory testing in disseminated intravascular coagulation.

    Science.gov (United States)

    Favaloro, Emmanuel J

    2010-06-01

    The diagnosis of disseminated intravascular coagulation (DIC) relies on clinical signs and symptoms, identification of the underlying disease, the results of laboratory testing, and differentiation from other pathologies. The clinical features mainly depend on the underlying cause of the DIC. The laboratory diagnosis of DIC uses a combination of tests because no single test result alone can firmly establish or rule out the diagnosis. Global tests of hemostasis may initially provide evidence of coagulation activation and later in the process provide evidence of consumption of coagulation factors, but their individual diagnostic efficiency is limited. Fibrinolytic markers, in particular D-dimer, are reflective of activation of both coagulation and fibrinolysis, so that a normal finding can be useful for ruling-out DIC. Decreased levels of the natural anticoagulants (in particular, antithrombin and protein C) are frequently observed in patients with DIC, but their measurement is not normally incorporated into standard diagnostic algorithms. New tests are being explored for utility in DIC, and some additional tests may be useful on a case-by-case basis, depending on the proposed cause of the DIC or their local availability. For example, clot waveform analysis is useful but currently limited to a single instrument. Also, procalcitonin is an inflammatory biomarker that may be useful within the context of septic DIC, and activated factor X clotting time is an emerging test of procoagulant phospholipids that also seems to hold promise in DIC.

  12. Genetically determined coagulation disorders in ischemic stroke

    NARCIS (Netherlands)

    M.P.J. van Goor (Marie-Louise)

    2004-01-01

    textabstractThe aim of the research described in this thesis was to investigate the role of genetically determined coagulation disorders in ischemic stroke. We therefore performed several retrospective studies and one prospective case-control study of patients with recent ischemic stroke (the COCOS

  13. Blood coagulation factor VIII: An overview

    Indian Academy of Sciences (India)

    G M Bhopale; R K Nanda

    2003-12-01

    Factor VIII (FVIII) functions as a co-factor in the blood coagulation cascade for the proteolytic activation of factor X by factor IXa. Deficiency of FVIII causes hemophilia A, the most commonly inherited bleeding disorder. This review highlights current knowledge on selected aspects of FVIII in which both the scientist and the clinician should be interested.

  14. Coagulation-flocculation studies of wastewaters

    NARCIS (Netherlands)

    Leentvaar, J.

    1982-01-01

    Although coagulation-flocculation processes have been practiced world-wide for almost a century in water treatment, several problems both in the theoretical and in the applied field have not been resolved yet. Especially interpretation of practical results with respect to governing coagula

  15. Haemostatic effects of recombinant coagulation factor VIIa

    NARCIS (Netherlands)

    Lisman, Johannes Antonius

    2002-01-01

    Recombinant coagulation factor VIIa (rFVIIa) has recently become available for treatment of patients with inhibitor-complicated haemophilia. It has been postulated that rFVIIa could become a universal haemostatic agent. Case reports and small studies confirm efficacy and safety of rFVIIa in a

  16. Blood coagulation: hemostasis and thrombin regulation.

    Science.gov (United States)

    Tanaka, Kenichi A; Key, Nigel S; Levy, Jerrold H

    2009-05-01

    Perioperative bleeding is a major challenge particularly because of increasing clinical use of potent antithrombotic drugs. Understanding current concepts of coagulation is important in determining the preoperative bleeding risk of patients, and in managing hemostatic therapy perioperatively. The serine protease thrombin plays pivotal roles in the activation of additional serine protease zymogens (inactive enzymatic precursors), cofactors, and cell-surface receptors. Thrombin generation is closely regulated to locally achieve rapid hemostasis after injury without causing uncontrolled systemic thrombosis. During surgery, there are major disturbances in coagulation and inflammatory systems because of hemorrhage/hemodilution, blood transfusion, and surgical stresses. Postoperative bleeding often requires allogeneic blood transfusions, which support thrombin generation and hemostasis. However, procoagulant activity and inflammation are increased postoperatively; thus, antithrombotic therapy may be required to prevent perioperative thrombotic complications. There have been significant advances in the management of perioperative hemostasis and thrombosis because of the introduction of novel hemostatic and antithrombotic drugs. However, a limitation of current treatment is that conventional clotting tests do not reflect the entire physiological processes of coagulation making optimal pharmacologic therapy difficult. Understanding the in vivo regulatory mechanisms and pharmacologic modulation of thrombin generation may help control bleeding without potentially increasing prothrombotic risks. In this review, we focus on the regulatory mechanisms of hemostasis and thrombin generation using multiple, simplified models of coagulation.

  17. Targeting exosites on blood coagulation proteases

    Directory of Open Access Journals (Sweden)

    Monteiro Robson Q.

    2005-01-01

    Full Text Available The high specificity of blood coagulation proteases has been attributed not only to residues surrounding the active site but also to other surface domains that are involved in recognizing and interacting with macromolecular substrates and inhibitors. Specific blood coagulation inhibitors obtained from exogenous sources such as blood sucking salivary glands and snake venoms have been identified. Some of these inhibitors interact with exosites on coagulation enzymes. Two examples are discussed in this short revision. Bothrojaracin is a snake venom-derived protein that binds to thrombin exosites 1 and 2. Complex formation impairs several exosite-dependent activities of thrombin including fibrinogen cleavage and platelet activation. Bothrojaracin also interacts with proexosite 1 on prothrombin thus decreasing the zymogen activation by the prothrombinase complex (FXa/FVa. Ixolaris is a two Kunitz tick salivary gland inhibitor, that is homologous to tissue factor pathway inhibitor. Recently it was demonstrated that ixolaris binds to heparin-binding exosite of FXa, thus impairing the recognition of prothrombin by the enzyme. In addition, ixolaris interacts with FX possibly through the heparin-binding proexosite. Differently from FX, the ixolaris-FX complex is not recognized as substrate by the intrinsic tenase complex (FIXa/FVIIIa. We conclude that these inhibitors may serve as tools for the study of coagulation exosites as well as prototypes for new anticoagulant drugs.

  18. Roles for vitamin K beyond coagulation

    Science.gov (United States)

    Recent interest in vitamin K has been motivated by evidence of physiological roles beyond that of coagulation. Vitamin K and vitamin K-dependent proteins may be involved in regulation of calcification, energy metabolism, and inflammation. However, the evidence for many of these proposed roles in the...

  19. Brownian coagulation at high particle concentrations

    NARCIS (Netherlands)

    Trzeciak, T. M.

    2012-01-01

    The process of Brownian coagulation, whereby particles are brought together by thermal motion and grow by collisions, is one of the most fundamental processes influencing the final properties of particulate matter in a variety of technically important systems. It is of importance in colloids, emulsi

  20. Summary of the Second Workshop on Liquid Argon Time Projection Chamber Research and Development in the United States

    Energy Technology Data Exchange (ETDEWEB)

    Acciarri, R. [Fermi National Accelerator Lab. (FNAL), Batavia, IL (United States); et al.

    2015-04-21

    The second workshop to discuss the development of liquid argon time projection chambers (LArTPCs) in the United States was held at Fermilab on July 8-9, 2014. The workshop was organized under the auspices of the Coordinating Panel for Advanced Detectors, a body that was initiated by the American Physical Society Division of Particles and Fields. All presentations at the workshop were made in six topical plenary sessions: i) Argon Purity and Cryogenics, ii) TPC and High Voltage, iii) Electronics, Data Acquisition and Triggering, iv) Scintillation Light Detection, v) Calibration and Test Beams, and vi) Software. This document summarizes the current efforts in each of these areas. It primarily focuses on the work in the US, but also highlights work done elsewhere in the world.

  1. Generation of stable and low-divergence 10-MeV quasimonoenergetic electron bunch using argon gas jet

    Directory of Open Access Journals (Sweden)

    M. Mori

    2009-08-01

    Full Text Available The pointing stability and divergence of a quasimonoenergetic electron bunch generated in a self-injected laser-plasma acceleration regime using 4 TW laser is studied. A pointing stability of 2.4 mrad root-mean-square (rms and a beam divergence of 10.6 mrad (rms were obtained using an argon gas-jet target for 50 sequential shots, while these values were degraded by a factor of 3 at the optimum condition using helium. The peak electron energies were 8.5±0.7 and 24.8±3.6  MeV using argon and helium, respectively. The experimental results indicate that the different propagation condition could be generated with the different material, although it is performed with the same irradiation condition.

  2. Surface wet-ability modification of thin PECVD silicon nitride layers by 40 keV argon ion treatments

    Science.gov (United States)

    Caridi, F.; Picciotto, A.; Vanzetti, L.; Iacob, E.; Scolaro, C.

    2015-10-01

    Measurements of wet-ability of liquid drops have been performed on a 30 nm silicon nitride (Si3N4) film deposited by a PECVD reactor on a silicon wafer and implanted by 40 keV argon ions at different doses. Surface treatments by using Ar ion beams have been employed to modify the wet-ability. The chemical composition of the first Si3N4 monolayer was investigated by means of X-ray Photoelectron Spectroscopy (XPS). The surface morphology was tested by Atomic Force Microscopy (AFM). Results put in evidence the best implantation conditions for silicon nitride to increase or to reduce the wet-ability of the biological liquid. This permits to improve the biocompatibility and functionality of Si3N4. In particular experimental results show that argon ion bombardment increases the contact angle, enhances the oxygen content and increases the surface roughness.

  3. Summary of the Second Workshop on Liquid Argon Time Projection Chamber Research and Development in the United States

    CERN Document Server

    Acciarri, R; Artrip, D; Baller, B; Bromberg, C; Cavanna, F; Carls, B; Chen, H; Deptuch, G; Epprecht, L; Dharmapalan, R; Foreman, W; Hahn, A; Johnson, M; Jones, B J P; Junk, T; Lang, K; Lockwitz, S; Marchionni, A; Mauger, C; Montanari, C; Mufson, S; Nessi, M; Back, H Olling; Petrillo, G; Pordes, S; Raaf, J; Rebel, B; Sinins, G; Soderberg, M; Spooner, N J C; Stancari, M; Strauss, T; Terao, K; Thorn, C; Tope, T; Toups, M; Urheim, J; Van de Water, R; Wang, H; Wasserman, R; Weber, M; Whittington, D; Yang, T

    2015-01-01

    The second workshop to discuss the development of liquid argon time projection chambers (LArTPCs) in the United States was held at Fermilab on July 8-9, 2014. The workshop was organized under the auspices of the Coordinating Panel for Advanced Detectors, a body that was initiated by the American Physical Society Division of Particles and Fields. All presentations at the workshop were made in six topical plenary sessions: $i)$ Argon Purity and Cryogenics, $ii)$ TPC and High Voltage, $iii)$ Electronics, Data Acquisition and Triggering, $iv)$ Scintillation Light Detection, $v)$ Calibration and Test Beams, and $vi)$ Software. This document summarizes the current efforts in each of these areas. It primarily focuses on the work in the US, but also highlights work done elsewhere in the world.

  4. Study of nuclear recoils in liquid argon with monoenergetic neutrons

    CERN Document Server

    Regenfus, C; Amsler, C; Creus, W; Ferella, A; Rochet, J; Walter, M

    2012-01-01

    For the development of liquid argon dark matter detectors we assembled a setup in the laboratory to scatter neutrons on a small liquid argon target. The neutrons are produced mono-energetically (E_kin=2.45 MeV) by nuclear fusion in a deuterium plasma and are collimated onto a 3" liquid argon cell operating in single-phase mode (zero electric field). Organic liquid scintillators are used to tag scattered neutrons and to provide a time-of-flight measurement. The setup is designed to study light pulse shapes and scintillation yields from nuclear and electronic recoils as well as from {\\alpha}-particles at working points relevant to dark matter searches. Liquid argon offers the possibility to scrutinise scintillation yields in noble liquids with respect to the populations of the two fundamental excimer states. Here we present experimental methods and first results from recent data towards such studies.

  5. A Study of the Residual 39Ar Content in Argon from Underground Sources

    CERN Document Server

    Xu, J; Galbiati, C; Goretti, A; Guray, G; Hohman, T; Holtz, D; Ianni, A; Laubenstein, M; Loer, B; Love, C; Martoff, C J; Montanari, D; Mukhopadhyay, S; Nelson, A; Rountree, S D; Vogelaar, R B; Wright, A

    2012-01-01

    The discovery of argon from underground sources with significantly less 39Ar than atmospheric argon was an important step in the development of direct-detection dark matter experiments using argon as the active target. We report on the design and operation of a low background detector with a single phase liquid argon target that was built to study the 39Ar content of the underground argon. Underground argon from the Kinder Morgan CO2 plant in Cortez, Colorado was determined to have less than 0.65% of the 39Ar activity in atmospheric argon.

  6. Optimized coagulation of high alkalinity, low temperature and particle water: pH adjustment and polyelectrolytes as coagulant aids.

    Science.gov (United States)

    Yu, Jianfeng; Wang, Dongsheng; Yan, Mingquan; Ye, Changqing; Yang, Min; Ge, Xiaopeng

    2007-08-01

    The Yellow River in winter as source water is characterized as high alkalinity, low temperature and low particle concentrations, which have brought many difficulties to water treatment plants. This study fully examines the optimized coagulation process of the Yellow River by conventional and pre-polymerized metal coagulants, pH adjustment and polyelectrolytes as the primary coagulants or coagulant aids. For all the metal coagulants, polyaluminum chlorides are superior to traditional metal coagulants due to their stable polymeric species and low consumption of alkalinity. The removal of natural organic matter by monomeric metal coagulants can be improved through pH adjustment, which is in accordance with the higher concentration of polymeric species formed at corresponding pH value. With the addition of polyelectrolytes as coagulant aids, the coagulation performance is significantly improved. The effective removal of dissolved organic matter is consistent with high charge density, while molecular weight is relatively important for removing particles, which is consistent with polyelectrolytes as primary coagulants. These results suggest that the coagulation mechanisms in the removal of dissolved organic matter and particles are different, which may be exploited for optimized coagulation for the typical source water in practice.

  7. Electron avalanches in liquid argon mixtures

    Energy Technology Data Exchange (ETDEWEB)

    Kim, J.G.; Dardin, S.M.; Kadel, R.W.; Kadyk, J.A.; Wenzel, W.B.; Peskov, V.

    2004-03-19

    We have observed stable avalanche gain in liquid argon when mixed with small amounts of xenon in the high electric field (>7 MV/cm) near the point of a chemically etched needle in a point-plane geometry. We identify two gain mechanisms, one pressure dependent, and the other independent of the applied pressure. We conclude that the pressure dependent signals are from avalanche gain in gas bubbles at the tip of the needle, while the pressure independent pulses are from avalanche gain in liquid. We measure the decay time spectra of photons from both types of avalanches. The decay times from the pressure dependent pulses decrease (increase) with the applied pressure (high voltage), while the decay times from the pressure independent pulses are approximately independent of pressure or high voltage. For our operating conditions, the collected charge distribution from avalanches is similar for 60 keV or 122 keV photon sources. With krypton additives, instead of Xe, we measure behavior consistent with only the pressure dependent pulses. Neon and TMS were also investigated as additives, and designs for practical detectors were tested.

  8. Size Determination of Argon Clusters from a Rayleigh Scattering Experiment

    Institute of Scientific and Technical Information of China (English)

    LEI An-Le; ZHAI Hua-Jin; LIU Bing-Chen; LI Zhong; NI Guo-Yuan; XU Zhi-Zhan

    2000-01-01

    Argon clusters are produced in the process of adiabatic expansion of a high backing pressure gas into vacuum through a nozzle. The cluster size is determined by a Rayleigh scattering measurement. The scattered signal measured is proportional to the 2.78th power of gas stagnation pressure. The average cluster sizes vary from 100 to more than 12000 atoms/cluster with the argon gas backing pressures ranging between 3 to 45 atm.

  9. Improvement of paint effluents coagulation using natural and synthetic coagulant aids.

    Science.gov (United States)

    Aboulhassan, M A; Souabi, S; Yaacoubi, A; Baudu, M

    2006-11-01

    The coagulant iron chloride and the flocculants Polysep 3000 (PO), Superfloc A-1820 (SU) and Praestol 2515 TR (PR) have been used in this study to show the efficiency of coagulation flocculation process in the chemical precipitation method for the removal of organic and colouring matters from the paint industry wastewater. This study also includes the amount of produced sludge. The results indicate that FeCl(3) is efficient at pH range 8-9 and at optimal dose of 650 mgl(-1). Iron chloride allows the removal of 82% of chemical oxygen demand (COD) and 94% of colour. However, sequential addition of coagulant and polymeric additives enhance clearly pollutant removal and produces less decanted sludge compared to the results obtained when the coagulant is used alone. The removal efficiency of COD reaches 91% and that of colour 99%. Coagulation-biflocculation process is more effective than the coagulation-monoflocculation one. The sequential addition of iron chloride, Polysep 3000 (cationic flocculant) and Praestol 2515 TR (anionic flocculant) seems to be the most suitable combination for the treatment of the paint industry wastewaters.

  10. Study on the removal of acid dyes using chitosan as a natural coagulant/coagulant aid.

    Science.gov (United States)

    Zonoozi, M H; Alavi Moghaddam, M R; Arami, M

    2011-01-01

    Chitosan was selected as a natural coagulating agent for the removal of acid dyes (Acid Blue 292; AB292, and Acid Red 398; AR398) from dye-containing solutions. The study was organised in two phases. In phase 1, chitosan was used alone as a natural coagulant for the removal of the dyes. For this purpose, the effect of different parameters including pH, chitosan dosage and initial dye concentration on the dye removal efficiency was examined. In phase 2 of the study, the application of chitosan as a natural coagulant aid in conjunction with polyaluminium chloride (PAC) was assessed. According to the results of phase 1, the best removal efficiencies occurred in an acidic pH range (less than 6) for both of the dyes. Also, excellent dye removal results (about 90%) were achieved with relatively low dosages of chitosan (30-35 mg L(-1) for AB292 and 50-60 mg L(-1) for AR398). However, the initial concentration of the dyes severely influenced the coagulation performance of chitosan, which can constrain the performance of chitosan as a natural coagulant. On the basis of the results of phase 2, chitosan, as a natural coagulant aid, noticeably enhanced the dye removal efficiency of PAC, especially in the case of AB292. Small amounts of chitosan (3 or 5 mg L(-1)) enhanced the dye removal efficiency of PAC up to 2.5 times for AB292.

  11. Enhanced coagulation for improving coagulation performance and reducing residual aluminum combining polyaluminum chloride with diatomite.

    Science.gov (United States)

    Hu, Wenchao; Wu, Chunde

    2016-01-01

    The feasibility of using enhanced coagulation, which combined polyaluminum chloride (PAC) with diatomite for improving coagulation performance and reducing the residual aluminum (Al), was discussed. The effects of PAC and diatomite dosage on the coagulation performance and residual Al were mainly investigated. Results demonstrated that the removal efficiencies of turbidity, dissolved organic carbon (DOC), and UV254 were significantly improved by the enhanced coagulation, compared with PAC coagulation alone. Meaningfully, the five forms of residual Al (total Al (TAl), total dissolved Al (TDAl), dissolved organic Al (DOAl), dissolved monomeric Al (DMAl), and dissolved organic monomeric Al (DOMAl)) all had different degrees of reduction in the presence of diatomite and achieved the lowest concentrations (0.185, 0.06, 0.053, 0.014, and 0 mg L(-1), respectively) at a PAC dose of 15 mg L(-1) and diatomite dose of 40 mg L(-1). In addition, when PAC was used as coagulant, the majority of residual Al existed in dissolved form (about 31.14-70.16%), and the content of DOMAl was small in the DMAl.

  12. Effects of argon gas flow rate on laser-welding.

    Science.gov (United States)

    Takayama, Yasuko; Nomoto, Rie; Nakajima, Hiroyuki; Ohkubo, Chikahiro

    2012-01-01

    The purpose of this study was to evaluate the effects of the rate of argon gas flow on joint strength in the laser-welding of cast metal plates and to measure the porosity. Two cast plates (Ti and Co-Cr alloy) of the same metal were abutted and welded together. The rates of argon gas flow were 0, 5 and 10 L/min for the Co-Cr alloy, and 5 and 10 L/min for the Ti. There was a significant difference in the ratio of porosity according to the rate of argon gas flow in the welded area. Argon shielding had no significant effect on the tensile strength of Co-Cr alloy. The 5 L/min specimens showed greater tensile strength than the 10 L/min specimens for Ti. Laser welding of the Co-Cr alloy was influenced very little by argon shielding. When the rate of argon gas flow was high, joint strength decreased for Ti.

  13. Power Consideration for Pulsed Discharges in Potassium Seeded Argon

    Institute of Scientific and Technical Information of China (English)

    XIA Sheng-Guo; HE Jun-Jia; LIU Ke-Fu

    2007-01-01

    Minimization of energy consumed in plasma generation is critical for applications, in which a large volume of plasmas is needed. We suggest that a high electron density atmospheric pressure plasmas can be generated by pulsed discharges in potassium seeded argon at an elevated temperature with a very small power input. The ionization efficiency and power budget of pulsed discharges in such plasmas are analytically studied. The results show that ionization efficiency of argon, especially at small reduced electric field E/N (the ratio of the electric field to the gas number density), is improved effectively in the presence of small amount of potassium additives. Power input of pulsed discharge to sustain a prescribed average level of ionization in potassium seeded argon is three orders of magnitude lower than that in pure argon. Further, unlike in pure argon, it is found that very short high-voltage pulses with very high repetition rates are unnecessary in potassium seeded argon. A pulse with 100ns of pulse duration, 5kHz of repetition rate, and 2Td (1 Td = 1 ×10-21 Vm2) of E/N is enough to sustain an electron density of 10l9m-3 in 1 atm 1500 K Ar+0.1% K mixture, with a very small power input of about 0.08 × 104 W/m3.

  14. THE IMPORTANCE OF COAGULATION BATH IN ACRYLIC FIBER PRODUCTION

    Directory of Open Access Journals (Sweden)

    İsmail TİYEK

    2005-03-01

    Full Text Available In the production of acrylic fibers using wet-spinning method, fiber formation takes places in the coagulation bath. Therefore, physical properties of the fibers, produced by the wet-spinning method, is affected by coagulation bath conditions. For this reason, coagulation bath parameters have to be checked very well. In this paper, both the physical events such as diffusion and phase transition, occured in the coagulation bath, and some coagulation bath parameters that affect these physical events are studied. Furthermore, it is tried to express their affects on the physical characteristics of the fibers.

  15. Unidentified coagulation disorders in post-tonsillectomy hemorrhage.

    Science.gov (United States)

    Windfuhr, Jochen P; Chen, Yue-Shih; Remmert, Stephan

    2004-01-01

    We conducted a retrospective study of 6,966 patients who had undergone tonsillectomy or adenotonsillectomy to evaluate the incidence and clinical features of previously unidentified coagulation disorders in patients who experienced postoperative hemorrhage (n = 201). We found that post-tonsillectomy hemorrhage secondary to unidentified coagulation disorders is extremely rare. However, normal coagulation values and an insignificant history do not rule out coagulation disorders. If diffuse, persistent, and bilateral bleeding is not related to arterial hypertension, dissection technique, or local infection, a rapid and detailed analysis of coagulation factors should be considered.

  16. Numerical Modeling of an RF Argon-Silane Plasma with Dust Particle Nucleation and Growth

    Science.gov (United States)

    Girshick, Steven; Agarwal, Pulkit

    2012-10-01

    We have developed a 1-D numerical model of an RF argon-silane plasma in which dust particles nucleate and grow. This model self-consistently couples a plasma module, a chemistry module and an aerosol module. The plasma module solves population balance equations for electrons and ions, the electron energy equation under the assumption of a Maxwellian velocity distribution, and Poisson's equation for the electric field. The chemistry module treats silane dissociation and reactions of silicon hydrides containing up to two silicon atoms. The aerosol module uses a sectional method to model particle size and charge distributions. The nucleation rate is equated to the rates of formation of anions containing two Si atoms, and a heterogeneous reaction model is used to model particle surface growth. Aerosol effects considered include particle charging, coagulation, and particle transport by neutral drag, ion drag, electric force, gravity and Brownian diffusion. Simulation results are shown for the case of a 13.56 MHz plasma at a pressure of 13 Pa and applied RF voltage of 100 V (amplitude), with flow through a showerhead electrode. These results show the strong coupling between the plasma and the spatiotemporal evolution of the nanoparticle cloud.

  17. In vitro effects of argon laser radiation on blood: quantitative and morphologic analysis

    Energy Technology Data Exchange (ETDEWEB)

    Abela, G.S.; Crea, F.; Smith, W.; Pepine, C.J.; Conti, C.R.

    1985-02-01

    Use of the argon laser to recanalize stenosed arteries may require delivery of the beam through blood. To assess the degree of hemolysis and debris formation, 84 samples of citrated whole blood were exposed to argon laser radiation with varying power (1, 2 and 3 watts) and duration (5, 10, 20 and 40 seconds). Compared with control samples, only blood samples exposed to a power of 3 watts for 40 seconds showed a marked decrease in hematocrit (from 37 +/- 1.3 to 33 +/- 1.4%, p less than 0.01) and a marked increase in both free hemoglobin concentration (from 0.2 +/- 0.2 to 1.3 +/- 0.5 g/100 ml, p less than 0.01) and debris weight (from 0.9 +/- 0.3 to 2.8 +/- 0.5 mg, p less than 0.01). Scanning electron microscopy of debris from samples of whole blood, washed erythrocytes and platelet-rich plasma lased at 3 watts for 40 seconds documented the presence of membrane denaturation of blood elements, resulting in their fusion to form complex mesh-like conglomerates. Similar morphologic changes were observed in whole blood samples exposed to a ''hot tip'' rather than laser radiation. These data indicate that: 1) argon laser radiation with a power of 3 watts does not produce apparent hemolysis or debris formation for exposure periods up to 20 seconds, and 2) the effects of laser radiation on blood are probably mediated by thermal denaturation of cell membranes, as suggested by the same morphologic changes produced by thermal injury from a ''hot tip.''

  18. New argon-argon (40Ar/39Ar) radiometric age dates from selected subsurface basalt flows at the Idaho National Laboratory, Idaho

    Science.gov (United States)

    Hodges, Mary K.; Turrin, Brent D.; Champion, Duane E.; Swisher, Carl C.

    2015-01-01

    In 2011, the U.S. Geological Survey, in cooperation with the U.S. Department of Energy, collected samples for 12 new argon-argon radiometric ages from eastern Snake River Plain olivine tholeiite basalt flows in the subsurface at the Idaho National Laboratory. The core samples were collected from flows that had previously published paleomagnetic data. Samples were sent to Rutgers University for argon-argon radiometric dating analyses.

  19. Communication: Trapping a proton in argon: Spectroscopy and theory of the proton-bound argon dimer and its solvation

    Science.gov (United States)

    McDonald, D. C.; Mauney, D. T.; Leicht, D.; Marks, J. H.; Tan, J. A.; Kuo, J.-L.; Duncan, M. A.

    2016-12-01

    Ion-molecule complexes of the form H+Arn are produced in pulsed-discharge supersonic expansions containing hydrogen and argon. These ions are analyzed and mass-selected in a reflectron spectrometer and studied with infrared laser photodissociation spectroscopy. Infrared spectra for the n = 3-7 complexes are characterized by a series of strong bands in the 900-2200 cm-1 region. Computational studies at the MP2/aug-cc-pVTZ level examine the structures, binding energies, and infrared spectra for these systems. The core ion responsible for the infrared bands is the proton-bound argon dimer, Ar-H+-Ar, which is progressively solvated by the excess argon. Anharmonic vibrational theory is able to reproduce the vibrational structure, identifying it as arising from the asymmetric proton stretch in combination with multiple quanta of the symmetric argon stretch. Successive addition of argon shifts the proton vibration to lower frequencies, as the charge is delocalized over more ligands. The Ar-H+-Ar core ion has a first solvation sphere of five argons.

  20. Evaluation of the process of coagulation/flocculation of produced water using Moringa oleifera Lam. as natural coagulant

    Energy Technology Data Exchange (ETDEWEB)

    Santana, C.R.; Pereira, D.F.; Sousa, S.C S N.; Silva, G.F. [Universidade Federal de Sergipe (UFSE), Sao Cristovao, SE (Brazil). Dept. de Engenharia Quimica], e-mail: claudia@ufs.br; Cavalcanti, E.B. [Universidade Tiradentes (UNIT), SE (Brazil). Inst. de Tecnologia e Pesquisa

    2010-07-15

    In the lifetime of an oil well, there comes a moment when a lot of water begins to be produced along with oil, either by the conditions of the reservoir, or as a result of water injection in the secondary recovery of the well. An important step in such process involves the treatment of the produced water by means of coagulation techniques. Therefore, the use of environmentally correct coagulants is presented as a viable alternative and has demonstrated advantages over the use of chemical coagulants. The plant of the genus Moringa, whose species is oleifera Lam, stands out as one of the most promising natural coagulants. The present study investigated the evaluation of the coagulation/flocculation of produced water, using seeds of Moringa oleifera Lam. as coagulant. The results were very significant, demonstrating that Moringa oleifera Lam. can be used as a natural coagulant in this type of treatment. (author)

  1. Design and Adaptation of an Optical System for Slit Lamp Delivery of a CO2 Laser Beam.

    Science.gov (United States)

    1981-12-01

    apply directly to the lasers used most d3+:Arban frequently in ocular surgery (CO2, Nd :YAG, ruby and argon ) and a potential surgical excimer laser (KrF...ophthalmologists -- the slit lamp . A reconfigured slit lamp , similar to the commercially made 900 Argon Laser Photo- coagulator, would be ideal (Ref 23). Such a...ADAill 108 AIR FORCE INST OF TECH WRIGHT-PATTERSON AFB OH SCHOO-ETC F/6 6/18 DESIGN AND ADAPTATION OF AN OPTICAL SYSTEM FOR SLIT LAMP DELIVE-ETC(U

  2. ATLAS One of the first Heavy ions collisions with stable beams- Event Display - November 2015

    CERN Multimedia

    ATLAS Collaboration

    2015-01-01

    One of the first heavy ions collisions with stable beams recorded by ATLAS in November 2015. Tracks reconstructed from hits in the inner tracking detector are shown as orange arcs curving in the solenoidal magnetic field. The green and yellow bars indicate energy deposits in the Liquid Argon and Scintillating Tile calorimeters respectively. The beam pipe and the inner detectors are also shown.

  3. A kinetic model of the electron-beam-pumped XeCl laser active medium

    Energy Technology Data Exchange (ETDEWEB)

    Boichenko, A.M.; Derzhiev, V.I.; Zhidkov, A.G.; Iakovlenko, S.I. (Institut Obshchei Fiziki, Moscow (USSR))

    1989-02-01

    Kinetic models are developed for XeCl laser active media in different buffer gases (helium, neon, and argon) pumped by an electron beam. In the calculations of the generation characteristics, allowance is made for the effect of the cavity field on the photoinduced transitions. The numerical results on the efficiency are in good agreement with experiments on electron beams. 17 refs.

  4. Evolution of Martian atmospheric argon: Implications for sources of volatiles

    Science.gov (United States)

    Hutchins, Kevin S.; Jakosky, Bruce M.

    We have examined processes affecting isotopes of argon (36Ar, 38Ar, 40Ar) in order to determine important atmospheric sources and sinks. Our simple model for argon evolution incorporates production of radiogenic argon in the mantle, outgassing of all argon species by extrusive and intrusive volcanism, and loss to space by knock-on sputtering above the exobase. Sputtering has been shown previously to be an important loss process for atmospheric species, especially isotopes of noble gases, which have few other mechanisms of escape. The integrated evolution of argon (36Ar, 38Ar, and 40Ar, respectively) is modeled in terms of these variables: (1) the planetary concentration of potassium, (2) the fraction of juvenile argon released catastrophically during the first 600 Myr., (3) potential variation in the time-history of sputtering loss from that suggested by Luhmann et al. [1992], and (4) the volume of total outgassing to the surface as compared to outgassing contributed by volcanic release. Our results indicate that Mars has lost between 85-95% of 36Ar and 70-88% of outgassed 40Ar. Due to this substantial loss, the planet must have outgassed the equivalent of between 10 and 100 times the total volume of gases released by extrusive and intrusive volcanics. This indicates that volcanic outgassing, alone, is insufficient to explain the present-day abundances of 36Ar and 40Ar in the Martian atmosphere. Similar calculations for 20Ne suggest outgassed volumes of between 100 and 1800 times in excess of that due to volcanism. This results in a distinct Ne/Ar elemental fractionation, with a preference for outgassing argon, of the order of 10 to 17. Although the results must be evaluated within the model uncertainties, the results are compelling in that they unequivocally show the existence of additional sources of atmospheric volatiles and helps define a means to identify them.

  5. Upgrade of the ATLAS Liquid Argon Calorimeters for the High-Luminosity LHC

    CERN Document Server

    McCarthy, Tom; The ATLAS collaboration

    2016-01-01

    The increased particle flux at the high luminosity phase of the Large Hadron Collider (HL-LHC), with instantaneous luminosities of up to 7.5 times the original design value, will have an impact on many sub-systems of the ATLAS detector. This contribution highlights the particular impacts on the ATLAS liquid argon calorimeter system, together with an overview of the various upgrade plans leading up to the HL-LHC. The higher luminosities are of particular importance for the forward calorimeters (FCal), where the expected increase in the ionization load poses a number of problems that can degrade the FCal performance such as beam heating and space-charge effects in the liquid argon gaps and high-voltage drop due to increased current drawn over the current-limiting resistors. A proposed FCal replacement as a way to counter some of these problems is weighed against the risks associated with the replacement. To further mitigate the effects of increased pile-up, the installation of a high-granularity timing detector...

  6. Upgrade of the ATLAS Liquid Argon Calorimeters for the High-Luminosity LHC arXiv

    CERN Document Server

    McCarthy, Thomas G.

    The increased particle flux at the high luminosity phase of the Large Hadron Collider (HL-LHC), with instantaneous luminosities of up to 7.5 times the original design value, will have an impact on many sub-systems of the ATLAS detector. This contribution highlights the particular impacts on the ATLAS liquid argon calorimeter system, together with an overview of the various upgrade plans leading up to the HL-LHC. The higher luminosities are of particular importance for the forward calorimeters (FCal), where the expected increase in the ionization load poses a number of problems that can degrade the FCal performance such as beam heating and space-charge effects in the liquid argon gaps and high-voltage drop due to increased current drawn over the current-limiting resistors. A proposed FCal replacement as a way to counter some of these problems is weighed against the risks associated with the replacement. To further mitigate the effects of increased pile-up, the installation of a high-granularity timing detector...

  7. Status of the Atlas Liquid Argon Calorimeter and its Performance after three years of LHC operation

    CERN Document Server

    De La Torre, H; The ATLAS collaboration

    2013-01-01

    The ATLAS experiment is designed to study the proton-proton collisions produced at the Large Hadron Collider(LHC) at CERN. Liquid argon sampling calorimeters are used for all electromagnetic calorimetry covering the pseudo-rapidity region up to 3.2, as well as for hadronic calorimetry in the range 1.4-4.9. The electromagnetic calorimeters use lead as passive material and are characterized by an accordion geometry that allows a fast and uniform azimuthal response without any gap. Copper and tungsten were chosen as passive material for the hadronic calorimetry; whereas a classic plate geometry was adopted at large polar angles, an innovative one based on cylindrical electrodes with thin argon gaps was designed for the coverage at low angles, where the particles flow is higher. All detectors are housed in three cryostats kept at 87 K. After installation in 2004-2006, the calorimeters were extensively commissioned over the three years period prior to first collisions in 2009, using cosmic rays and single LHC beam...

  8. Measurement of Scintillation and Ionization Yield and Scintillation Pulse Shape from Nuclear Recoils in Liquid Argon

    CERN Document Server

    Cao, H; Avetisyan, R; Back, H O; Cocco, A G; DeJongh, F; Fiorillo, G; Galbiati, C; Grandi, L; Guardincerri, Y; Kendziora, C; Lippincott, W H; Love, C; Lyons, S; Manenti, L; Martoff, C J; Meng, Y; Montanari, D; Mosteiro, P; Olvitt, D; Pordes, S; Qian, H; Rossi, B; Saldanha, R; Sangiorgio, S; Siegl, K; Strauss, S Y; Tan, W; Tatarowicz, J; Walker, S; Wang, H; Watson, A W; Westerdale, S; Yoo, J

    2014-01-01

    We have measured the scintillation and ionization yield of recoiling nuclei in liquid argon as a function of applied electric field by exposing a dual-phase Liquid Argon Time Projection Chamber (LAr-TPC) to a low energy pulsed narrowband neutron beam produced at the Notre Dame Institute for Structure and Nuclear Astrophysics. Liquid scintillation counters were arranged to detect and identify neutrons scattered in the TPC and to select the energy of the recoiling nuclei. We report measurements of the scintillation and ionization yields for nuclear recoils with energies from 10.3 to 57.2 keV and for applied electric fields from 0 to 1000 V/cm. We also report the observation of an anti-correlation between scintillation and ionization from nuclear recoils, which is similar to the anti-correlation between scintillation and ionization from electron recoils. A comparison of the light and charge yield of recoils parallel and perpendicular to the applied electric field yielded a first evidence of sensitivity to direct...

  9. ATLAS Liquid Argon Endcap Calorimeter R and D for sLHC

    CERN Document Server

    Schacht, P; The ATLAS collaboration

    2009-01-01

    The performance of the ATLAS liquid argon endcap has been studied for luminosities as expected for the operation at sLHC. The increase of integrated luminosity by a factor of ten has serious consequences for the signal reconstruction, radiation hardness requirements and operation of the forward liquid argon calorimeters. The response has been studied with small modules of the type as built for ATLAS in a very high intensity beam at IHEP/Protvino. The highest intensity obtained was well above the level of energy impact expected for ATLAS at sLHC. The signal processing of the ATLAS Hadronic Endcap Calorimeters employs the concept of 'active pads' which keeps the detector capacities at the input of the amplifiers small and thereby achieves a fast rise time of the signal. This concept is realized using highly integrated amplifier and summing chips in GaAs technology. With an increase of luminosity by a factor of ten the safety factor for the radiation hardness is essentially eliminated. Therefore new more radiati...

  10. ATLAS Liquid Argon Endcap Calorimeter R and D for sLHC

    CERN Document Server

    Schacht, P; The ATLAS collaboration

    2009-01-01

    The performance of the ATLAS liquid argon endcap has been studied for luminosities as expected for the operation at sLHC. The increase of integrated luminosity by a factor of ten has serious consequences for the signal reconstruction, radiation hardness requirements and operations of the forward liquid argon calorimeters. The response has been studied with small modules of the type as built for ATLAS in a very high intensity beam at IHEP/Protvino. The highest intensity obtained was well above the level of energy impact expected for ATLAS at sLHC. The signal processing of the ATLAS Hadronic Endcap Calorimeter employs the concept of 'active pads' which keeps the detector capacities at the input of the amplifiers small and thereby achieves a fast rise time of the signal. This concept is realized using highly integrated amplifier and summing chips in GaAs technology. With an increase of luminosity by a factor of ten the safety factor for the radiation hardness is essentially eliminated. Therefore new more radiati...

  11. [Disseminated intravascular coagulation: clinical and biological diagnosis].

    Science.gov (United States)

    Touaoussa, Aziz; El Youssi, Hind; El Hassani, Imane; Hanouf, Daham; El Bergui, Imane; Zoulati, Ghizlane; Amrani Hassani, Moncef

    2015-01-01

    Disseminated intravascular coagulation (DIC) is a syndrome characterized by the systemic activation of blood coagulation. Its pathophysiological mechanisms are complex and dependent on the underlying pathology, making the clinical and biological expression of quite variable DIC. Among the various biological parameters disrupted, most are not specific, and none of them allows in itself to make the diagnosis. All this does not facilitate the task of the practitioner for diagnosis of overt DIC, much less that of the non-overt DIC, early stage whose treatment would improve the prognosis. These considerations have led to develop scores, combining several parameters depending on their availability in daily practice, as well as their diagnostic relevance. Of all the scores, the ISTH (International society of thrombosis and hemostasis) remains the most used.

  12. EFFECTS OF ORAL CONTRACEPTIVES ON COAGULATING FACTORS

    Directory of Open Access Journals (Sweden)

    H.R. Sadeghipour Roudsari.

    1997-06-01

    Full Text Available Thirty young, healthy, nonsmoking women (mean age approximately 28 years taking low-dose oral contraceptive pills were recruited for the study of the effects of these pills on coagulating factors. Twenty subjects were taking LD pill (Ethinyl estradiol 0.03 mg, levonorgestrel 0.15 mg and 10 others were taking Cilest (Ethinyl estradiol 0.035 mg, Norgestimate 0.25 mg for six months. The control subjects did not receive any oral contraceptives or other medications. Our results showed that:"n1. There is no significant difference between the effects of LD and Cilest (with a different progestin content on coagulating factors."n2. No significant changes were observed between both LD users and controls in PT, APTT, and fibrinogen levels."n3. No significant changes were observed between both Cilest users and controls in PT, APTT, and fibrinogen levels."n

  13. Self-similar behavior for multicomponent coagulation

    Institute of Scientific and Technical Information of China (English)

    杨曼丽; 卢志明; 刘宇陆

    2014-01-01

    Self-similar behavior for the multicomponent coagulation system is investi-gated analytically in this paper. Asymptotic self-similar solutions for the constant ker-nel, sum kernel, and product kernel are achieved by introduction of different generating functions. In these solutions, two size-scale variables are introduced to characterize the asymptotic distribution of total mass and individual masses. The result of product kernel (gelling kernel) is consistent with the Vigli-Ziff conjecture to some extent. Furthermore, the steady-state solution with injection for the constant kernel is obtained, which is again the product of a normal distribution and the scaling solution for the single variable coag-ulation.

  14. Coagulation of dust particles in a plasma

    Science.gov (United States)

    Horanyi, M.; Goertz, C. K.

    1990-01-01

    The electrostatic charge of small dust grains in a plasma in which the temperature varies in time is discussed, pointing out that secondary electron emission might introduce charge separation. If the sign of the charge on small grains is opposite to that on big ones, enhanced coagulation can occur which will affect the size distribution of grains in a plasma. Two scenarios where this process might be relevant are considered: a hot plasma environment with temperature fluctuations and a cold plasma environment with transient heating events. The importance of the enhanced coagulation is uncertain, because the plasma parameters in grain-producing environments such as a molecular cloud or a protoplanetary disk are not known. It is possible, however, that this process is the most efficient mechanism for the growth of grains in the size range of 0.1-500 microns.

  15. Can dust coagulation trigger streaming instability?

    CERN Document Server

    Drazkowska, Joanna

    2014-01-01

    Streaming instability can be a very efficient way of overcoming growth and drift barriers to planetesimal formation. However, it was shown that strong clumping, which leads to planetesimal formation, requires a considerable number of large grains. State-of-the-art streaming instability models do not take into account realistic size distributions resulting from the collisional evolution of dust. We investigate whether a sufficient quantity of large aggregates can be produced by sticking and what the interplay of dust coagulation and planetesimal formation is. We develop a semi-analytical prescription of planetesimal formation by streaming instability and implement it in our dust coagulation code based on the Monte Carlo algorithm with the representative particles approach. We find that planetesimal formation by streaming instability may preferentially work outside the snow line, where sticky icy aggregates are present. The efficiency of the process depends strongly on local dust abundance and radial pressure g...

  16. Ventricular metastasis resulting in disseminated intravascular coagulation

    Directory of Open Access Journals (Sweden)

    Davis Ian D

    2005-05-01

    Full Text Available Abstract Background Disseminated Intravascular Coagulation (DIC complicates up to 7% of malignancies, the commonest solid organ association being adenocarcinoma. Transitional Cell Carcinoma (TCC has rarely been associated with DIC. Case presentation A 74-year-old woman with TCC bladder and DIC was found to have a cardiac lesion suspicious for metastatic disease. The DIC improved with infusion of plasma and administration of Vitamin K, however the cardiac lesion was deemed inoperable and chemotherapy inappropriate; given the patients functional status. We postulate that direct activation of the coagulation cascade by the intraventricular metastasis probably triggered the coagulopathy in this patient. Conclusion Cardiac metastases should be considered in cancer patients with otherwise unexplained DIC. This may influence treatment choices.

  17. [Disseminated intravascular coagulation in solid tumours].

    Science.gov (United States)

    Ferrand, François Régis; Garcia-Hejl, Carine; Moussaid, Yassine; Schernberg, Antoine; Bidard, François-Clément; Pavic, Michel; Khenifer, Safia; Stoclin, Annabelle

    2014-06-01

    Disseminated intravascular coagulation (DIC) is a complex abnormality of hemostasis with dramatic consequences and long described as associated with tumors. Yet the diagnosis and management of paraneoplastic DIC are poorly defined. The purpose of this paper is to review DIC associated with solid tumors, at the pathophysiological and therapeutic levels in particular. We also report data from a recent retrospective series of patients with DIC in the context of a solid tumor, to illustrate the epidemiological, clinical and prognostic.

  18. Rennet coagulation of heated milk concentrates

    OpenAIRE

    Schreiber, Regina; Hinrichs, Jörg

    2000-01-01

    International audience; The high temperature heating of cheese milk is a useful tool for preventing late fermentation during cheese ripening if the renneting properties remain unchanged. The aim of the investigations was to find heating conditions which guarantee the inactivation of clostridia spores but still enable rennet coagulation of the heated milk and milk concentrates respectively. The gel strength of the rennet gels increased the more the casein content increased. The native whey pro...

  19. Modelling Coagulation Systems: A Stochastic Approach

    CERN Document Server

    Ryazanov, V V

    2011-01-01

    A general stochastic approach to the description of coagulating aerosol system is developed. As the object of description one can consider arbitrary mesoscopic values (number of aerosol clusters, their size etc). The birth-and-death formalism for a number of clusters can be regarded as a partial case of the generalized storage model. An application of the storage model to the number of monomers in a cluster is discussed.

  20. Coagulation Factor IX for Hemophilia B Therapy


    OpenAIRE

    Orlova, N.; Kovnir, S.; Vorobiev, I.; Gabibov, A.

    2012-01-01

    Factor IX is a zymogen enzyme of the blood coagulation cascade. Inherited absence or deficit of the IX functional factor causes bleeding disorder hemophilia B, which requires constant protein replacement therapy. Reviewed herein are the current state in the manufacturing of FIX, improved variants of the recombinant protein for therapy, transgenic organisms for obtaining FIX, and the advances in the gene therapy of hemophilia B.

  1. Electrocoagulation versus chemical coagulation: coagulation/flocculation mechanisms and resulting floc characteristics.

    Science.gov (United States)

    Harif, Tali; Khai, Moti; Adin, Avner

    2012-06-15

    Electrocoagulation (EC) and chemical coagulation (CC) are employed in water treatment for particle removal. Although both are used for similar purposes, they differ in their dosing method - in EC the coagulant is added by electrolytic oxidation of an appropriate anode material, while in CC dissolution of a chemical coagulant is used. These different methods in fact induce different chemical environments, which should impact coagulation/flocculation mechanisms and subsequent floc formation. Hence, the process implications when choosing which to apply should be significant. This study elucidates differences in coagulation/flocculation mechanisms in EC versus CC and their subsequent effect on floc growth kinetics and structural evolution. A buffered kaolin suspension served as a representative solution that underwent EC and CC by applying aluminum via additive dosing regime in batch mode. In EC an aluminum anode generated the active species while in CC, commercial alum was used. Aluminum equivalent doses were applied, at initial pH values of 5, 6.5 and 8, while samples were taken over pre-determined time intervals, and analyzed for pH, particle size distribution, ζ potential, and structural properties. EC generated fragile flocs, compared to CC, over a wider pH range, at a substantially higher growth rate, that were prone to restructuring and compaction. The results suggest that the flocculation mechanism governing EC in sweep floc conditions is of Diffusion Limited Cluster Aggregation (DCLA) nature, versus a Reaction Limited Cluster Aggregation (RLCA) type in CC. The implications of these differences are discussed.

  2. Disseminated intravascular coagulation: testing and diagnosis.

    Science.gov (United States)

    Wada, Hideo; Matsumoto, Takeshi; Yamashita, Yoshiki; Hatada, Tsuyoshi

    2014-09-25

    Abnormalities of the hemostatic system in patients with DIC result from the sum of vectors for hypercoagulation and hyperfibrinolysis. DIC is classified into hyperfibrinolysis, hypercoagulation, massive bleeding or nonsymptomatic types according to the balance of the two vectors. Both the antithrombin (AT) and protein C (PC) levels are significantly low in patients with septic DIC, and reduced amounts of AT and PC result in the lack of inhibition of thrombin and activated FVIII, respectively. Thrombin activates FVIII, while activated FVIII accelerates the coagulation pathway to generate thrombin; thus activation of the coagulation system persists. Three sets of diagnostic criteria have been established by the Japanese Ministry of Health, Labour and Welfare, International Society of Thrombosis and Haemostasis and Japanese Association for Acute Medicine, respectively. Although these three diagnostic criteria score hemostatic abnormalities using similar global coagulation tests, the sensitivity and/or specificity for death differ. Treatment with AT or activated PC may not improve the outcomes of patients with sepsis at the early stage, although they may improve the outcomes in those with DIC. Therefore, new diagnostic criteria for determining the appropriate time to initiate anticoagulant treatment are required.

  3. Coagulation factor VIII activity in diabetic patients

    Directory of Open Access Journals (Sweden)

    Nermina Babić

    2011-02-01

    Full Text Available Aim To examine coagulation factor VIII activity in plasma, as a risk factor for thrombosis, in the patients with diabetes mellitus (DM. Also, to assess its relationship with ibrinogen and fasting blood glucose concentrations and with body mass index. Methods The plasma coagulation factor VIII activity, plasma levels of ibrinogen and blood glucose concentrations were measured in 30 patients with DM type 1, 30 patients with DM type 2 and in 30 healthy subjects. Body weight and body height were also measured and BMI was calculated.Results The plasma factor VIII activity in patients with DM type 1 and patients with DM type 2 was signiicantly higher than the values measured in healthy subjects. There was no signiicant difference in the factor VIII activity between patients with DM type 1 and type 2. The concentrations of ibrinogen and blood glucose in both groups of patients were signiicantly higher than in the group of healthy subjects. Patients with DM type 2 had a signiicantly higher BMI compared to healthy subjects, as well as compared to patients with DM type 1. There was a signiicant positive correlation between plasma factor VIII activity and plasma level of ibrinogen and a signiicant negative correlation between factor VIII activity and BMI in patients with DM type 2. Conclusion Diabetic patients have the elevated plasma coagulation factor VIII activity and increased ibrinogen concentration thus an increased risk of thrombosis and vascular diseases.

  4. Laser frequency bandwidth narrowing by photorefractive two-beam coupling.

    Science.gov (United States)

    Chomsky, D; Sternklar, S; Zigler, A; Jackel, S

    1992-04-01

    We present a theoretical analysis and experimental demonstration of a new method for spectral narrowing of laser radiation. The bandwidth narrowing is experienced by a laser beam subjected to a photorefractive two-beam coupling process. Contrary to the conventional method of frequency filtering by a Fabry-Perot étalon, this technique has no intrinsic finesse limitation on its resolution. A factor of 2 in frequency bandwidth narrowing is achieved with an argon-ion laser.

  5. The Spectroscopic Detectability of Argon in the Lunar Atmosphere

    CERN Document Server

    Parker, J W; Gladstone, G R; Shull, J M; Parker, Joel Wm.

    1999-01-01

    Direct measurements of the abundance of argon in the lunar atmosphere were made in 1973 by instruments placed on the Moon during the Apollo 17 mission, but the total daytime abundance is unknown due to instrument saturation effects; thus, until we are able to return to the Moon for improved direct measurements, we must use remote sensing to establish the daytime abundance. In this paper, we present a complete analysis of the potential for measuring argon in the lunar atmosphere via emission-line or absorption-line observations. We come to the surprising conclusion that the lower limit established by the in situ lunar argon measurements implies that any absorption-line measurement of argon in the lower, dayside lunar atmosphere requires analysis in the optically-thick regime. In light of this result, we present the results of our EUVS sounding rocket observations of the lunar occultation of Spica, which provide a new upper limit on the abundance of argon in the daytime lunar atmosphere. We also re-analyze a re...

  6. Irradiation damage simulation of Zircaloy-4 using argon ions bombardment

    Institute of Scientific and Technical Information of China (English)

    Dequan Peng; Xinde Bai; Feng Pan

    2008-01-01

    To simulate irradiation damage, argon ion was implanted in the Zircaloy-4 with the fluence ranging from 1×1016 to 1×1017 cm-2, using accelerating implanter at an extraction voltage of 190 kV and liquid nitrogen temperature. Then the influence of argon ion implantation on the aqueous corrosion behavior of Zircaloy-4 was studied. The valence states of elements in the surface layer of the samples wcrc analyzed using X-ray photoelectron spectroscopy (XPS). Transmission clcctron microscopy (TEM) was used to examine the microstructure of the argon-implanted samples. The potentiodynamic polarization technique was employed to evaluate the aqueous corrosion resistance of implanted Zircaloy-4 in 1 mol/L H2SO4 solution. It is found that there appear bubbles on the surface of the samples when the argon flucncc is 1×1016 cm-2. The microstructure of argon-implanted samples changes from amor-phous to partial amorphous, then to polycrystallinc, and again to amorphous. The corrosion resistance of implanted samples linearly declines with the increase of flucnce approximately, which is attributed to the linear increase of the irradiation damage.

  7. The Molecular Pathway of Argon-Mediated Neuroprotection

    Directory of Open Access Journals (Sweden)

    Felix Ulbrich

    2016-10-01

    Full Text Available The noble gas argon has attracted increasing attention in recent years, especially because of its neuroprotective properties. In a variety of models, ranging from oxygen-glucose deprivation in cell culture to complex models of mid-cerebral artery occlusion, subarachnoid hemorrhage or retinal ischemia-reperfusion injury in animals, argon administration after individual injury demonstrated favorable effects, particularly increased cell survival and even improved neuronal function. As an inert molecule, argon did not show signs of adverse effects in the in vitro and in vivo model used, while being comparably cheap and easy to apply. However, the molecular mechanism by which argon is able to exert its protective and beneficial characteristics remains unclear. Although there are many pieces missing to complete the signaling pathway throughout the cell, it is the aim of this review to summarize the known parts of the molecular pathways and to combine them to provide a clear insight into the cellular pathway, starting with the receptors that may be involved in mediating argons effects and ending with the translational response.

  8. Characteristics of Knock in Hydrogen-Oxygen-Argon SI Engine

    Energy Technology Data Exchange (ETDEWEB)

    Killingsworth, N; Rapp, V; Flowers, D; Aceves, S; Chen, J; Dibble, R

    2010-02-23

    A promising approach for improving the efficiency of internal combustion engines is to employ a working fluid with a high specific heat ratio such as the noble gas argon. Moreover, all harmful emissions are eliminated when the intake charge is composed of oxygen, nonreactive argon, and hydrogen fuel. Previous research demonstrated indicated thermal efficiencies greater than 45% at 5.5 compression ratio in engines operating with hydrogen, oxygen, and argon. However, knock limits spark advance and increasing the efficiency further. Conditions under which knock occurs in such engines differs from typical gasoline fueled engines. In-cylinder temperatures using hydrogen-oxygen-argon are higher due to the high specific heat ratio and pressures are lower because of the low compression ratio. Better understanding of knock under these conditions can lead to operating strategies that inhibit knock and allow operation closer to the knock limit. In this work we compare knock with a hydrogen, oxygen, and argon mixture to that of air-gasoline mixtures in a variable compression ratio cooperative fuels research (CFR) engine. The focus is on stability of knocking phenomena, as well as, amplitude and frequency of the resulting pressure waves.

  9. Treatment of Leachate by Coagulation-Flocculation using different Coagulants and Polymer: A Review

    Directory of Open Access Journals (Sweden)

    Lee Mao Rui

    2012-01-01

    Full Text Available Leachate will be treated by using coagulation-flocculation. Coagulation and flocculation are essential processes in a number of diverse disciplines, including biochemistry, cheese manufacturing, rubber manufacturing, and in water and waste water treatment. It is effective for removing high concentration organic pollutant and heavy metals in wastewater. However, coagulationflocculation examined the effectiveness of alum, ferric chloride and polyaluminum chloride (PAC1  as well as the use of synthetic polymers on the removal of suspended solid (SS, color, COD and ammoniacal nitrogen (NH3N from leachate. The coagulant dosage has typically been determined through jar test, which requires a long experiment time in a field water treatment plant.

  10. Update on the high speed serializer ASIC development for ATLAS Liquid Argon calorimeter upgrade

    CERN Document Server

    Liu, T; The ATLAS collaboration

    2011-01-01

    We have been developing a serializer application-specific integrated circuit (ASIC) based on a commercial 0.25-μm silicon-on-sapphire (SOS) CMOS technology for the ATLAS liquid argon calorimeter front-end electronics upgrade. The first prototype, a 5 Gbps 16:1 serializer has been designed, fabricated, and tested in lab environment and in a 200 MeV proton beam. The test results indicate that the first prototype meets the design goals. The second prototype, a double-lane, 8 Gbps per lane serializer is under development. The post-layout simulation indicates that 8 Gbps is achievable. In this paper we present the design and the test results of the first prototype and the design and status of the second prototype.

  11. A high speed serializer ASIC for ATLAS Liquid Argon calorimeter upgrade

    CERN Document Server

    Liu, T; The ATLAS collaboration

    2014-01-01

    We have been developing a serializer application-specific integrated circuit (ASIC) based on a commercial 0.25-μm silicon-on-sapphire (SOS) CMOS technology for the ATLAS liquid argon calorimeter front-end electronics upgrade. The first prototype, a 5 Gbps 16:1 serializer has been designed, fabricated, and tested in lab environment and in 200 MeV proton beam. The test results indicate that the first prototype meets the design goals. The second prototype, a double-lane, 8 Gbps per lane serializer is under development. The post layout simulation indicates that 8 Gbps is achievable. In this paper we present the design and the test results of the first prototype and the design and status of the second prototype.

  12. Observation of {Delta}n=1 dielectronic recombination resonances of boronlike argon

    Energy Technology Data Exchange (ETDEWEB)

    Zong, W. [Stockholm Univ. (Sweden). Dept. of Atomic Phys.; DeWitt, D.R. [Stockholm Univ. (Sweden). Dept. of Atomic Phys.; Schuch, R. [Stockholm Univ. (Sweden). Dept. of Atomic Phys.; Gao, H. [Stockholm Univ. (Sweden). Dept. of Atomic Phys.; Asp, S. [Stockholm Univ. (Sweden). Dept. of Atomic Phys.; Justiniano, E. [East Carolina Univ., Greenville, NC (United States). Dept. of Physics

    1996-02-01

    We report here an observation of {Delta}n=1 dielectronic recombination resonances of boron-like argon in the energy region 140-195 eV. With the cooler`s electron beam as a target, a resolution of approximately 0.6 eV FWHM was obtained in the observed energy range. The energies of the doubly excited states were estimated with a Hartree-Fock calculation, which indicates that the observed resonances are from Ar{sup 13+}(1s{sup 2}2s{sup 2}2p) to Ar{sup 12+}(1s{sup 2}2s{sup 2}3l3l`) and Ar{sup 12+}(1s{sup 2}2s2p3l3l`) transitions. (orig.).

  13. Spatially Resolved Measurements of a Double Layer in an Argon Helicon Plasma

    Science.gov (United States)

    Aguirre, Evan; Siddiqui, Umair; McKee, John; Scime, Earl

    2015-11-01

    We report 2-dimensional, spatially resolved observations of a double layer in an expanding helicon plasma. These new measurements investigate the origins of previously observed multiple ion beam populations in the downstream plasma. We use Laser Induced Fluorescence (LIF) to measure the ion velocity distribution functions (IVDFs) of argon ions and neutrals both parallel and perpendicular to the background magnetic field and an rf-compensated Langmuir probe to determine the local plasma potential. These are the first multi-dimensional LIF measurements of ion acceleration in a current-free double layer and were obtained with a recently installed, internal scanning probe system in the HELIX-LEIA experimental facility. This work is supported by US National Science Foundation grant number PHY-1360278.

  14. Comparisons of the Electron and Muon Testbeam Response of the ATLAS Liquid Argon Calorimeters with GEANT4 Simulations

    CERN Document Server

    Benchekroun, D; Karapetian, G V; Kiryunin, A E; Kish, J; Kordas, K; Leltchouk, M; Loch, P; Mazini, R; Negroni, S; Parrour, G; Salihagic, D; Seligman, W; Soukharev, A M; Strízenec, P; Unal, G

    2004-01-01

    GEANT4, a new simulation toolkit, is now in use by the different sub-detectors which are currently being built and tested for the ATLAS experiment. The validation of the GEANT4 electromagnetic physics is done by comparing the response of the various modules of the ATLAS liquid argon calorimeters to electron and muon test beams to the results of GEANT4 simulations. Comparisons to the corresponding GEANT3 predictions has been done as well. This note presents the status of the work on this validation.

  15. Precise 3D track reconstruction algorithm for the ICARUS T600 liquid argon time projection chamber detector

    CERN Document Server

    Antonello, M

    2013-01-01

    Liquid Argon Time Projection Chamber (LAr TPC) detectors offer charged particle imaging capability with remarkable spatial resolution. Precise event reconstruction procedures are critical in order to fully exploit the potential of this technology. In this paper we present a new, general approach of three-dimensional reconstruction for the LAr TPC with a practical application to track reconstruction. The efficiency of the method is evaluated on a sample of simulated tracks. We present also the application of the method to the analysis of real data tracks collected during the ICARUS T600 detector operation with the CNGS neutrino beam.

  16. Precise 3D Track Reconstruction Algorithm for the ICARUS T600 Liquid Argon Time Projection Chamber Detector

    Directory of Open Access Journals (Sweden)

    M. Antonello

    2013-01-01

    Full Text Available Liquid Argon Time Projection Chamber (LAr TPC detectors offer charged particle imaging capability with remarkable spatial resolution. Precise event reconstruction procedures are critical in order to fully exploit the potential of this technology. In this paper we present a new, general approach to 3D reconstruction for the LAr TPC with a practical application to the track reconstruction. The efficiency of the method is evaluated on a sample of simulated tracks. We present also the application of the method to the analysis of stopping particle tracks collected during the ICARUS T600 detector operation with the CNGS neutrino beam.

  17. A prototype liquid Argon Time Projection Chamber for the study of UV laser multi-photonic ionization

    CERN Document Server

    Rossi, B; Ereditato, A; Haug, S; Hanni, R; Hess, M; Janos, S; Juget, F; Kreslo, I; Lehmann, S; Lutz, P; Mathieu, R; Messina, M; Moser, U; Nydegger, F; Schutz, H U; Weber, M S; Zeller, M

    2009-01-01

    This paper describes the design, realization and operation of a prototype liquid Argon Time Projection Chamber (LAr TPC) detector dedicated to the development of a novel online monitoring and calibration system exploiting UV laser beams. In particular, the system is intended to measure the lifetime of the primary ionization in LAr, in turn related to the LAr purity level. This technique could be exploited by present and next generation large mass LAr TPCs for which monitoring of the performance and calibration plays an important role. Results from the first measurements are presented together with some considerations and outlook.

  18. Disseminated intravascular coagulation in a patient with metastatic prostate cancer: Fatal outcome following strontium-89 therapy

    Energy Technology Data Exchange (ETDEWEB)

    Leong, C.; McKenzie, R.; Coupland, D.B. [Univ. of British Columbia, (Canada)] [and others

    1994-10-01

    A patient with metastatic prostate cancer was found to have low-grade disseminated intravascular coagulation (DIC). He had significant bone pain despite external-beam radiotherapy and was given {sup 89}Sr with subsequent thrombocytopenia and epistaxis. The patient died from generalized hemorrhage 36 days postinjection. Although it is not possible to establish a causal relationship between {sup 89}Sr and DIC, practitioners should be alert to complications associated with the primary disorder which might occur at a time to raise concern about the intervention. 8 refs., 1 tab.

  19. A comprehensive model for the humoral coagulation network in humans.

    Science.gov (United States)

    Wajima, T; Isbister, G K; Duffull, S B

    2009-09-01

    Coagulation is an important process in hemostasis and comprises a complicated interaction of multiple enzymes and proteins. We have developed a mechanistic quantitative model of the coagulation network. The model accurately describes the time courses of coagulation factors following in vivo activation as well as in vitro blood coagulation tests of prothrombin time (PT, often reported as international normalized ratio (INR)) and activated partial thromboplastin time (aPTT). The model predicts the concentration-time and time-effect profiles of warfarin, heparins, and vitamin K in humans. The model can be applied to predict the time courses of coagulation kinetics in clinical situations (e.g., hemophilia) and for biomarker identification during drug development. The model developed in this study is the first quantitative description of the comprehensive coagulation network.

  20. Coagulation, flocculation. Organic polymers and their use; Coagulation, floculation. Les polymeres organiques et leurs utilisations

    Energy Technology Data Exchange (ETDEWEB)

    Charbonnier, H. [SNF Floerger, Saint Etienne (France)

    1997-12-31

    Used for specific pollutions, and less onerous in their use, organic polymers can be employed alone or in combination with inorganic products in order to meet legal standards or to reduce the volume of the sludges formed. Two major families of polymers can be distinguished according to the stage of the process in which they are used: coagulants and flocculants, these two uses corresponding to very different characteristics. A coagulant must provide the maximum of electrical charges in order to destabilize colloidal suspensions, whilst a flocculant must make it possible to collect small particles into conglomerates which are easier to filter out. (authors)

  1. Attenuation measurements of vacuum ultraviolet light in liquid argon revisited

    Energy Technology Data Exchange (ETDEWEB)

    Neumeier, A. [Physik-Department E15, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany); Dandl, T.; Himpsl, A. [Physik-Department E12, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany); Hofmann, M. [Physik-Department E15, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany); KETEK GmbH, Hofer Straße 3, 81737 München (Germany); Oberauer, L.; Potzel, W.; Schönert, S. [Physik-Department E15, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany); Ulrich, A., E-mail: andreas.ulrich@ph.tum.de [Physik-Department E12, Technische Universität München, James-Franck-Straße 1, 85748 Garching (Germany)

    2015-11-11

    The attenuation of vacuum ultraviolet light in liquid argon in the context of its application in large liquid noble gas detectors has been studied. Compared to a previous publication several technical issues concerning transmission measurements in general are addressed and several systematic effects were quantitatively measured. Wavelength-resolved transmission measurements have been performed from the vacuum ultraviolet to the near-infrared region. On the current level of sensitivity with a length of the optical path of 11.6 cm, no xenon-related absorption effects could be observed, and pure liquid argon is fully transparent down to the short wavelength cut-off of the experimental setup at 118 nm. A lower limit for the attenuation length of pure liquid argon for its own scintillation light has been estimated to be 1.10 m based on a very conservative approach.

  2. Attenuation measurements of vacuum ultraviolet light in liquid argon revisited

    CERN Document Server

    Neumeier, A; Himpsl, A; Hofmann, M; Oberauer, L; Potzel, W; Schönert, S; Ulrich, A

    2015-01-01

    The attenuation of vacuum ultraviolet light in liquid argon in the context of its application in large liquid noble gas detectors has been studied. Compared to a previous publication several technical issues concerning transmission measurements in general are addressed and several systematic effects were quantitatively measured. Wavelength-resolved transmission measurements have been performed from the vacuum ultraviolet to the near-infrared region. On the current level of sensitivity with a length of the optical path of 11.6 cm, no xenon-related absorption effects could be observed, and pure liquid argon is fully transparent down to the short wavelength cut-off of the experimental setup at 118 nm. A lower limit for the attenuation length of pure liquid argon for its own scintillation light has been estimated to be 1.10 m based on a very conservative approach.

  3. Studies of Electron Avalanche Behavior in Liquid Argon

    CERN Document Server

    Kim, J G; Jackson, K H; Kadel, R W; Kadyk, J A; Peskov, Vladimir; Wenzel, W A

    2002-01-01

    Electron avalanching in liquid argon is being studied as a function of voltage, pressure, radiation intensity, and the concentrations of certain additives, especially xenon. The avalanches produced in an intense electric field at the tip of a tungsten needle are initiated by ionization from a moveable americium (241Am) gamma ray source. Photons from xenon excimers are detected as photomultiplier signals in coincidence with the current pulse from the needle. In pure liquid argon the avalanche behavior is erratic, but the addition of even a small amount of xenon (>100ppm) stabilizes the performance. Similar attempts with neon (30%) as an additive to argon have been unsuccessful. Tests with higher energy gamma rays (57Co) yield spectra and other performance characteristics quite similar to those using the 241Am source. Two types of signal pulses are commonly observed: a set of pulses that are sensitive to ambient pressure, and a set of somewhat smaller pulses that are not pressure dependent.

  4. Scintillation time dependence and pulse shape discrimination in liquid argon

    CERN Document Server

    Lippincott, W H; Gastler, D; Hime, A; Kearns, E; McKinsey, D N; Nikkel, J A; Stonehill, L C

    2008-01-01

    Using a single-phase liquid argon detector with a signal yield of 4.85 photoelectrons per keV of electronic-equivalent recoil energy (keVee), we measure the scintillation time dependence of both electronic and nuclear recoils in liquid argon down to 5 keVee. We develop two methods of pulse shape discrimination to distinguish between electronic and nuclear recoils. Using one of these methods, we measure a background and statistics-limited level of electronic recoil contamination to be $7.6\\times10^{-7}$ between 60 and 128 keV of nuclear recoil energy (keVr) for a nuclear recoil acceptance of 50% with no nuclear recoil-like events above 72 keVr. Finally, we develop a maximum likelihood method of pulse shape discrimination using the measured scintillation time dependence and predict the sensitivity to WIMP-nucleon scattering in three configurations of a liquid argon dark matter detector.

  5. Liquid Argon Calorimetry with LHC-Performance Specifications

    CERN Multimedia

    2002-01-01

    % RD-3 Liquid Argon Calorimetry with LHC-Performance Specifications \\\\ \\\\Good electromagnetic and hadronic calorimetry will play a central role in an LHC detector. Among the techniques used so far, or under development, the liquid argon sampling calorimetry offers high radiation resistence, good energy resolution (electromagnetic and hadronic), excellent calibration stability and response uniformity. Its rate capabilities, however, do not yet match the requirements for LHC. \\\\ \\\\The aim of this proposal is to improve the technique in such a way that high granularity, good hermiticity and adequate rate capabilities are obtained, without compromising the above mentioned properties. To reach this goal, we propose to use a novel structure, the $^{\\prime\\prime}$accordion$^{\\prime\\prime}$, coupled to fast preamplifiers working at liquid argon temperature. Converter and readout electrodes are no longer planar and perpendicular to particles, as usual, but instead they are wiggled around a plane containing particles. ...

  6. On the Electric Breakdown in Liquid Argon at Centimeter Scale

    CERN Document Server

    Auger, M; Ereditato, A; Goeldi, D; Janos, S; Kreslo, I; Luethi, M; von Rohr, C Rudolf; Strauss, T; Weber, M S

    2015-01-01

    We present a study on the dependence of electric breakdown discharge parameters on electrode geometry and the breakdown field in liquid argon near its boiling point. The measurements were performed with a spherical cathode and a planar anode at distances ranging from 0.1 mm to 10.0 mm. A detailed study of the time evolution of the breakdown volt-ampere characteristics was performed for the first time. It revealed a slow streamer development phase in the discharge. The results of a spectroscopic study of the visible light emission of the breakdowns complement the measurements. The light emission from the initial phase of the discharge is attributed to electro-luminescence of liquid argon following a current of drifting electrons. These results contribute to set benchmarks for breakdown-safe design of ionization detectors, such as Liquid Argon Time Projection Chambers (LAr TPC).

  7. The Simulation of the ATLAS Liquid Argon Calorimetry

    CERN Document Server

    Archambault, J P; Carli, T; Costanzo, D; Dell'Acqua, A; Djama, F; Gallas, M; Fincke-Keeler, M; Khakzad, M; Kiryunin, A; Krieger, P; Leltchouk, M; Loch, P; Ma, H; Menke, S; Monnier, E; Nairz, A; Niess, V; Oakham, G; Oram, C; Pospelov, G; Rajagopalan, S; Rimoldi, A; Rousseau, D; Rutherfoord, J; Seligman, W; Soukharev, A; Strízenec, P; Tóth, J; Tsukerman, I; Tsulaia, V; Unal, G; Grahn, K J

    2008-01-01

    In ATLAS, all of the electromagnetic calorimetry and part of the hadronic calorimetry is performed by a calorimeter system using liquid argon as the active material, together with various types of absorbers. The liquid argon calorimeter consists of four subsystems: the electromagnetic barrel and endcap accordion calorimeters; the hadronic endcap calorimeters, and the forward calorimeters. A very accurate geometrical description of these calorimeters is used as input to the Geant 4-based ATLAS simulation, and a careful modelling of the signal development is applied in the generation of hits. Certain types of Monte Carlo truth information ("Calibration Hits") may, additionally, be recorded for calorimeter cells as well as for dead material. This note is a comprehensive reference describing the simulation of the four liquid argon calorimeteter components.

  8. A therapeutic experience on Port Wine hemangiomas with Argon Laser

    Directory of Open Access Journals (Sweden)

    Farahvash M

    1997-09-01

    Full Text Available Port wine stains are benign but cosmetically devasting congenital angiomas. The argon laser is a therapeutic device newly applied to this condition. Our program was begun 6 years ago. From the beginning, the study was conceived as a clinical investigation of both the port wine stain and its argon laser therapy. A total of 218 patients with port wine stains have been studied and many aspects of their clinical condition detailed. Employing the Argon laser, test spots have been carried out in patients and the results have been analyzed with clinical aspects of the lesions. Altogether, 501 treatments were performed in 218 patients. Good to excellent results were obtained in 81 patients. Moderate Result was obtained in 31 weak result in 65 patients. Most common complication were hyperpigmentation and depressed scar.

  9. Enzymic Milk Coagulation: Casein Micelle Aggregation and Curd Formation

    OpenAIRE

    McMahon, Donald J.

    1983-01-01

    Enzymic milk coagulation was monitored by measuring changes in curd firmness and apparent absorbance of undiluted milk. Detection of coagulation, visually or rheologically, occurred after the milk changes from a system of aggregating particles to an extended space network. This change was observed as a shoulder in apparent absorbance plots and coagulation time was defined as the critical point in the aggregation process analogously to non-linear condensation polymerization reactions. It corre...

  10. Computer Simulation of Influence of Sedimentation on Rapid Coagulation

    Institute of Scientific and Technical Information of China (English)

    孙祉伟; 陈致英

    2003-01-01

    A computer simulation was performed to explore the features and effects of sedimentation on rapid coagulation.To estimate the accumulated influence of gravity on coagulation for dispersions, a sedimentation influence ratio is defined. Some factors possibly related to the influence of sedimentation were considered in the simulation and analysed by comparing the size distribution of aggregates, the change in collision number, and coagulation rates at different gravity levels (0 g, 1 g and more with g being the gravitational constant).

  11. Measurement of Longitudinal Electron Diffusion in Liquid Argon

    CERN Document Server

    Li, Yichen; Thorn, Craig; Qian, Xin; Diwan, Milind; Joshi, Jyoti; Kettell, Steve; Morse, William; Rao, Triveni; Stewart, Jim; Tang, Wei; Viren, Brett

    2015-01-01

    We report the measurement of longitudinal electron diffusion coefficients in liquid argon for electric fields between 100 and 2000 V/cm with a gold photocathode as a bright electron source. The measurement principle, apparatus, and data analysis are described. Our results, which are consistent with previous measurements in the region between 100 to 350 V/cm [1] , are systematically higher than the prediction of Atrazhev-Timoshkin[2], and represent the world's best measurement in the region between 350 to 2000 V/cm. The quantum efficiency of the gold photocathode, the drift velocity and longitudinal diffusion coefficients in gas argon are also presented.

  12. Rotational spectrum and dynamics of tetrahydrofuran-argon

    Energy Technology Data Exchange (ETDEWEB)

    Melandri, S.; Favero, P.G.; Caminati, W. [Dipartimento di Chimica ' G. Ciamician' dell' Universita, Via Selmi 2, I-40126 Bologna (Italy); Lopez, J.C.; Alonso, J.L. [Departamento de Quimica-Fisica, Facultad de Ciencias, Universidad de Valladolid, E-47005 Valladolid (Spain)

    1998-12-15

    The jet-cooled rotational spectrum of the tetrahydrofuran-argon molecular complex has been investigated by millimeter-wave absorption and Fourier transform microwave spectroscopies. The argon atom is located nearly over the oxygen atom, almost perpendicularly to the COC plane. Each rotational transition is split in two component lines due to the residual pseudorotational effects of the ring in the complex. The splitting between the two vibrational sublevels has been calculated to be 111.345(44) MHz. (Copyright (c) 1998 Elsevier Science B.V., Amsterdam. All rights reserved000.

  13. The Erosion of Frozen Argon by Swift Helium Ions

    DEFF Research Database (Denmark)

    Besenbacher, F.; Bøttiger, Jørgen; Graversen, O.

    1981-01-01

    The temperature, energy, and thickness dependence of the erosion rates of frozen argon films when irradiated with 0.1–3 MeV helium ions have been measured. The erosion yields Y are much too high to be explained by the concentional collisional cascade-sputtering theory and are furthermore unequivo......The temperature, energy, and thickness dependence of the erosion rates of frozen argon films when irradiated with 0.1–3 MeV helium ions have been measured. The erosion yields Y are much too high to be explained by the concentional collisional cascade-sputtering theory and are furthermore...

  14. Breakdown voltage of metal-oxide resistors in liquid argon

    CERN Document Server

    Bagby, L F; James, C C; Jones, B J P; Jostlein, H; Lockwitz, S; Naples, D; Raaf, J L; Rameika, R; Schukraft, A; Strauss, T; Weber, M S; Wolbers, S A

    2014-01-01

    We characterized a sample of metal-oxide resistors and measured their breakdown voltage in liquid argon by applying high voltage (HV) pulses over a 3 second period to simulate the electric breakdown in a HV-divider chain. All resistors had higher breakdown voltages in liquid argon than their vendor ratings in air at room temperature. Failure modes range from full destruction to coating damage. In cases where breakdown was not catastrophic, subsequent breakdown voltages were lower in subsequent measuring runs. One resistor type withstands 131\\,kV pulses, the limit of the test setup.

  15. Attosecond-correlated dynamics of two electrons in argon

    Indian Academy of Sciences (India)

    V Sharma; N Camus; B Fischer; M Kremer; A Rudenko; B Bergues; M Kuebel; N G Johnson; M F Kling; T Pfeifer; J Ullrich; R Moshammer

    2014-01-01

    In this work we explored strong field-induced decay of doubly excited transient Coulomb complex Ar** → Ar2++2. We measured the correlated two-electron emission as a function of carrier envelop phase (CEP) of 6 fs pulses in the non-sequential double ionization (NSDI) of argon. Classical model calculations suggest that the intermediate doubly excited Coulomb complex loses memory of its formation dynamics. We estimated the ionization time difference between the two electrons from NSDI of argon and it is 200 ± 100 as (N Camus et al, Phys. Rev. Lett. 108, 073003 (2012)).

  16. Recovery of struvite via coagulation and flocculation using natural compounds.

    Science.gov (United States)

    Latifian, Maryam; Liu, Jing; Mattiasson, Bo

    2014-01-01

    One of the major setbacks of struvite recovery processes is the difficulty in harvesting struvite crystals. This study evaluates the use of different coagulants to improve precipitation of struvite (MgNH4PO4.6H20) crystals. Chitosan and poly(diallyldimethyl ammonium chloride) (Poly-DADMAC) as a coagulant-flocculent and alginate and bentonite as a coagulant aid have been examined in jar tests. Also, a continuous three-phase process, i.e., struvite crystallization, coagulation/flocculation and precipitation process, was set up for real wastewater. Addition of chitosan as the coagulant and bentonite as the coagulant aid was significantly more efficient in forming struvite flocs in comparison to Poly-DADMAC alone or with coagulant aid, which did not show any positive effect. The calculated average settling velocity of struvite with chitosan-bentonite addition in synthetic and in real wastewater increased by approximately 5.3 and 2.8 folds, respectively, compared with that of no coagulant/flocculent addition. Phosphorus recovery of over 70% was achieved by the continuous process. Findings in this study clearly confirmed the possibility of using chitosan and bentonite as an efficient coagulant-flocculent to enhance the recovery of struvite crystals.

  17. Effect of cyanobacterial peptides and proteins on coagulation of kaolinite

    Directory of Open Access Journals (Sweden)

    Kateřina Novotná

    2016-12-01

    Full Text Available Coagulation of peptides and proteins produced by the cyanobacterium Microcystis aeruginosa and their influence on the coagulation of hydrophobic kaolinite particles were investigated. For this purpose, the dose of ferric sulphate used as the coagulant was optimized and jar tests with kaolinite, peptides/proteins and both kaolinite and peptides/proteins were carried out under different pH conditions. At pH 4–5.5, the peptides/proteins were efficiently coagulated and peptides/proteins were also found to contribute to the coagulation of kaolinite particles at this pH. Charge neutralization and adsorption were found to be the dominant coagulation mechanisms. The coagulation efficiency and the character of the prevailing coagulation mechanism were strongly dependent on the charge characteristics of the peptides/proteins, kaolinite and hydrolysis products of iron, thus on the pH value. At a pH of about 6, the coagulation process deteriorated due to the formation of soluble Fe-peptide/protein complexes.

  18. Compound bioflocculant and polyaluminum chloride in kaolin-humic acid coagulation: factors influencing coagulation performance and floc characteristics.

    Science.gov (United States)

    Li, Ruihua; Gao, Baoyu; Huang, Xin; Dong, Hongyu; Li, Xiaochen; Yue, Qinyan; Wang, Yan; Li, Qian

    2014-11-01

    The objective of this study was to investigate the influence of coagulant dosage and pH on coagulation performance and floc properties using polyaluminum chloride (PAC) and compound bioflocculant (CBF) dual-coagulant in kaolin-humic acid (HA) treatment. Results showed that as PAC dosage rose, comparatively better coagulation efficiencies and floc characteristics were achieved due to stronger charge neutralization and sweeping effect. Addition of CBF could enhance coagulation performance and floc properties, including size, strength and recoverability, except fractal dimension. Solution pH had a significant effect on coagulation efficiencies and flocs formation. Under acidic condition, flocs showed higher strength and recoverability but lower fractal dimension, where charge neutralization was the foremost mechanism. More compact flocs were generated under alkaline condition due to the sweeping effect of hydrolyzed Al species. Copyright © 2014 Elsevier Ltd. All rights reserved.

  19. Coagulation profile of liquid-state plasma.

    Science.gov (United States)

    Gosselin, Robert C; Marshall, Carol; Dwyre, Denis M; Gresens, Chris; Davis, Diana; Scherer, Lynette; Taylor, Douglas

    2013-03-01

    Use of liquid plasma (LP) has been reported as early as the mid 1930s. Unlike fresh-frozen plasma (FFP), LP is maintained at 1 to 6°C for up to 40 days after collection and processing. Despite its approved use by the US Food and Drug Administration, the coagulation profile of LP is incompletely described. In this study we evaluate the coagulation profile of LP stored up to 30 days. LP was prepared by removing plasma from nonleukoreduced whole blood within 24 hours of collection. Three LP units from each ABO group were collected and stored at 1 to 6°C. Plasma aliquots were obtained at Postcollection Days 1 to 5, 10, 15, 20, 25, and 30 and then stored at -70°C. Each aliquot was tested for prothrombin time, activated partial thromboplastin time, and other coagulation and fibrinolytic factors. There was a significant decrease in Factor (F)V, FVII, FVIII, von Willebrand factor (VWF), protein S (PS) activity, and endogenous thrombin potential on Day 15 compared with Day 1. No significant difference was observed for PS antigen, D-dimer, or thrombin-antithrombin complex. At least 50% activity of all measured factors was noted on Day 15, compared to Day 1. Considerable heterogeneity was observed between the different blood groups for FVII, FVIII, and VWF. These data demonstrate that LP maintains at least 50% of factor activity and thrombin-generating capacity up to 15 days of refrigerated storage. It may be more appropriate to limit LP storage and supplement with FFP when used for management of massively bleeding patients. © 2012 American Association of Blood Banks.

  20. The effect of garlic on coagulation tests

    Directory of Open Access Journals (Sweden)

    MA. Yeganeh

    2007-01-01

    Full Text Available Abstract Background and purpose: There are many reports on anti-thrombotic properties of garlic. Also, regarding the simultaneous consumption of garlic and Warfarine or non-steroid anti-inflammatory drugs (NSAIDs, some warning recommendations are published. The aim of present study was to evaluate the effects of garlic on coagulation tests, and in case of any demonstrative anticoagulation effect, the patients, particularly those with coagulation disorders, could be given appropriate advice on proper consumption of garlic.Materials and Methods: This was a clinical trial in which 50 volunteer students were selected based on information collected using appropriate questionnaires. The students were tested for coagulation assays including bleeding time (BT, clotting time (CT, prothrombin time (PT, partial thromboplastin time (PIT, clot retraction (CR, and platelets count (PC before and after consumption of garlic. Data were analyzed using SPPS and T-test. The average values of tests obtained in two stages of experiment were further compared statistically. Results: The results of our study on subjects (30 females and 20 males with an average age of 21.7 years showed that there was no significant change in values obtained for CT, PT, PC and CR (p>0.05 following consumption of garlic. However, a significant increase in PTT values was found following consumption of garlic (the p values for samples collected after 24 hours and 4 hours were 0.001 and 0.012 respectively. There was also a significant difference (p=0.027 in BT 24 hours after garlic consumption. Regarding the results of similar tests among two genders, no significant difference was found.Conclusion: Following consumption of garlic, there was a significant increase in PIT and BT, the effect being more obvious after 24 hours. The data of present study regarding the inhibitory effect of garlic on platelet activities is consistent with those reported by some other researches which is also

  1. A concept of the photon collider beam dump

    CERN Document Server

    Shekhtman, L I

    2014-01-01

    Photon beams at photon colliders are very narrow, powerful (10--15 MW) and cannot be spread by fast magnets (because photons are neutral). No material can withstand such energy density. For the ILC-based photon collider, we suggest using a 150 m long, pressurized (P ~ 4 atm) argon gas target in front of a water absorber which solves the overheating and mechanical stress problems. The neutron background at the interaction point is estimated and additionally suppressed using a 20 m long hydrogen gas target in front of the argon.

  2. Coagulation-Inflammatory Network: Anti-inflammatory Effect of Natural Coagulation Inhibitors

    Institute of Scientific and Technical Information of China (English)

    贺石林

    2001-01-01

    @@ Considerable evidence has accumulated to indicated that the serine protease in blood clotting process not only participate in the activation of coagulation factors,but also result in a series of cell responses particularly involved in inflammation process through appropriate receptors.

  3. Study on coagulation property of metal-polysilicate coagulants in low turbidity water treatment

    Institute of Scientific and Technical Information of China (English)

    杨海燕; 崔福义; 赵庆良; 马超

    2004-01-01

    In order to remove the low turbidity present in surface water, a novel metal-polysilicate coagulant was used to treat the raw water taken from Tanjiang River in Guangdong Province. This study on the effects of A1/Fe molar ratio on the performance of a complex compound formed by polysilicic acid, aluminium and ferric salt (PAFS) showed that PAFS with A1/Fe ratio of 10:3 seemed to have the best coagulation performance in removing turbidity and color. Experimental results showed that under the conditions of polymerization time of 15 d, sedimentation time of 12 min, and pH of 6-8,PAFS with A1/Fe molar ratio of 10:3 had the best coagulation efficiency and lowest residual A1 concentration. The turbidity decreased from 23.8 NTU to 3.23 NTU and the residual A1 concentration was only 0.165 mg/L in the product water. It could be speculated that colloidal impurities and particulate A1 were removed by adsorption bridging and electrical neutralization of long chain inorganic polymer coagulants.

  4. Study on coagulation property of metal-polysilicate coagulants in low turbidity water treatment

    Institute of Scientific and Technical Information of China (English)

    杨海燕; 崔福义; 赵庆良; 马超

    2004-01-01

    In order to remove the low turbidity present in surface water, a novel metal-polysilicate coagulant was used to treat the raw water taken from Tanjiang River in Guangdong Province. This study on the effects of Al/Fe molar ratio on the performance of a complex compound formed by polysilicic acid, aluminium and ferric salt (PAFS) showed that PAFS with Al/Fe ratio of 10:3 seemed to have the best coagulation performance in removing turbidity and color. Experimental results showed that under the conditions of polymerization time of 15 d, sedimentation time of 12 min, and pH of 6(8, PAFS with Al/Fe molar ratio of 10:3 had the best coagulation efficiency and lowest residual Al concentration. The turbidity decreased from 23.8 NTU to 3.23 NTU and the residual Al concentration was only 0.165 mg/L in the product water. It could be speculated that colloidal impurities and particulate Al were removed by adsorption bridging and electrical neutralization of long chain inorganic polymer coagulants.

  5. Tissue regenerating functions of coagulation factor XIII

    DEFF Research Database (Denmark)

    Soendergaard, C; Kvist, P H; Seidelin, J B;

    2013-01-01

    The protransglutaminase factor XIII (FXIII) has recently gained interest within the field of tissue regeneration, as it has been found that FXIII significantly influences wound healing by exerting a multitude of functions. It supports haemostasis by enhancing platelet adhesion to damaged......-receptor 2 and the αVβ3 integrin is important for angiogenesis supporting formation of granulation tissue. Chronic inflammatory conditions involving bleeding and activation of the coagulation cascade have been shown to lead to reduced FXIII levels in plasma. Of particular importance for this review...

  6. The Diagnosis and Man Disseminated Intravascular Coagulation

    Institute of Scientific and Technical Information of China (English)

    Flelcher B.; Taylor.Jr

    2003-01-01

    @@ This review describes disseminated intravascular coagulation(DIC) as a syndrome in which hemostatic factors are activated and products are generated. This syndrome ranges in severity from an obvious decompensated coagulopathy (overt-DIC) to the subclinical compensated activation of hemostatic factors(non-overt DIC). Ths first part of this review emphasizes two points: First, activation of the hemostatic system is controlled by a vast network of capillaries and venules through anticoagulant and antiinflammatory regulatory factors that operate from the endothelium( e. G. , protein C and thrombomodulin, tissue factor pathway inhibitor).

  7. New data on electron-beam purification of wastewater

    Energy Technology Data Exchange (ETDEWEB)

    Pikaev, A.K. E-mail: pikaev@ipc.rssi.ru

    2002-11-01

    Recent environmental applications of radiation technology, developed in the author's laboratory, are presented in this paper. They are electron-beam and coagulation purification of molasses distillery slops from distillery-produced ethyl alcohol by fermentation of plant materials, electron-beam purification of wastewater from carboxylic acids (for example, formic acid) and removal of petroleum products (diesel fuel, motor oil and residual fuel oil) from water by {gamma}-irradiation.

  8. New data on electron-beam purification of wastewater

    Science.gov (United States)

    Pikaev, A. K.

    2002-11-01

    Recent environmental applications of radiation technology, developed in the author's laboratory, are presented in this paper. They are electron-beam and coagulation purification of molasses distillery slops from distillery-produced ethyl alcohol by fermentation of plant materials, electron-beam purification of wastewater from carboxylic acids (for example, formic acid) and removal of petroleum products (diesel fuel, motor oil and residual fuel oil) from water by γ-irradiation.

  9. 内镜下氩离子凝固术联合高频电刀治疗胃肠息肉的体会%Endoscopic Argonion Coagulation Technique Combined High-frequency Electrotome Experience for the Treatment of Gastrointestinal Polyps

    Institute of Scientific and Technical Information of China (English)

    张小敏

    2013-01-01

    Objective To explore the endoscopic argon ion coagulation technique combined high-frequency electrotome for the treatment of gastrointestinal polyps. Methods Using the endoscopic argon ion coagulation technique combined high-frequency electrotome resection of gastrointestinal polyps. Results 3~6 months after treatment tracking patients with endoscopic check after half an year, no complications occurred, polyp recurrence under endoscopy. Conclusion The argon ion coagulation technique with high frequency electric knife therapy gastrointestinal polyp is a kind of safe, easy and effective method of endoscopic treatment.%目的:探讨内镜下氩离子凝固术联合高频电刀治疗胃肠息肉的效果。方法采用内镜下氩离子凝固术联合高频电刀切除胃肠息肉。结果治疗后3~6个月追踪患者并于半年后复查内镜,无并发症发生,内镜下未见息肉复发。结论氩离子凝固术联合高频电刀治疗胃肠息肉是一种安全、简便、有效的内镜下治疗方法。

  10. Laser-induced vibrational dynamics of ozone in solid argon

    DEFF Research Database (Denmark)

    Hansen, Flemming Yssing; Amstrup, B.; Henriksen, Niels Engholm

    1997-01-01

    We consider the vibrational dynamics, induced by an intense infrared laser pulse, in an ozone molecule with isotopic substitution, that is, (OOO)-O-16-O-16-O-18 and compare the dynamics in the gas phase and in solid ar on. not perturbed by argon on a time-scale of a few picoseconds and selective...

  11. Behavior of Excited Argon Atoms in Inductively Driven Plasmas

    CERN Document Server

    Hebner, G A

    1999-01-01

    Laser induced fluorescence has been used to measure the spatial distribution of the two lowest energy argon excited states, 1s sub 5 and 1s sub 4 , in inductively driven plasmas containing argon, chlorine and boron trichloride. The behavior of the two energy levels with plasma conditions was significantly different, probably because the 1s sub 5 level is metastable and the 1s sub 4 level is radiatively coupled to the ground state but is radiation trapped. The argon data is compared with a global model to identify the relative importance of processes such as electron collisional mixing and radiation trapping. The trends in the data suggest that both processes play a major role in determining the excited state density. At lower rfpower and pressure, excited state spatial distributions in pure argon were peaked in the center of the discharge, with an approximately Gaussian profile. However, for the highest rfpowers and pressures investigated, the spatial distributions tended to flatten in the center of the disch...

  12. Human-chromosome alterations induced by argon laser treatment

    Energy Technology Data Exchange (ETDEWEB)

    Simi, S.; Colella, C. (Consiglio Nazionale delle Ricerche, Pisa (Italy). Lab. di Mutagenesi e Differenziamento); Agati, G.; Fusi, F. (Florence Univ. (Italy). Ist. di Farmacologia); Corsi, M.F.; Pratesi, R. (Consiglio Nazionale delle Ricerche, Florence (Italy). Lab. di Elettronica Quantistica); Tocco, G.A. (Naples Univ. (Italy). Ist. di Istologia ed Embrilogia)

    1984-07-01

    The possible occurrence of genetic damage arising from exposure of human cells to visible laser light has been evaluated in PHA-stimulated human lymphocytes. Aneuploidy and chromosome aberrations have been observed after exposure to an argon laser. These findings appear of special interest in view of the possible role of these chromosome alterations in carcinogenesis.

  13. A 2-Dimensional Fluid Model for an Argon Rf Discharge

    NARCIS (Netherlands)

    Passchier, J. D. P.; W. J. Goedheer,

    1993-01-01

    A fluid model for an argon rf discharge in a cylindrical discharge chamber is presented. The model contains the particle balances for electrons and ions and the electron energy balance. A nonzero autobias voltage is obtained by imposing the condition that the time-averaged current toward the powered

  14. Thermal decomposition of Yttrium(III) isovalerate in argon

    DEFF Research Database (Denmark)

    Grivel, Jean-Claude; Yue, Zhao; Tang, Xiao;

    2016-01-01

    The thermal behaviour of yttrium(III) isovalerate (Y(C4H9CO2)3) was studied in argon by means of thermogravimetry, differential thermal analysis, FTIR-spectroscopy, hot-stage optical microscopy and X-ray diffraction with a laboratory Cu-tube source as well as with a synchrotron radiation source...

  15. Thermal decomposition of yttrium(III) valerate in argon

    DEFF Research Database (Denmark)

    Grivel, Jean-Claude; Yue, Zhao; Tang, Xiao;

    2014-01-01

    The thermal decomposition of yttrium(III) valerate (Y(C4H9CO2)3) was studied in argon by means of thermogravimetry, differential thermal analysis, IR-spectroscopy, X-ray diffraction, in-situ synchrotron diffraction and hot-stage microscopy as well as room temperature optical microscopy. Melting...

  16. Characterising argon-bomb balloons for high-speed photography

    CSIR Research Space (South Africa)

    Olivier, M

    2013-08-01

    Full Text Available A method to optimise the geometry, explosive charge mass and volume of an argon bomb for specific lighting requirements has been proposed. The method is specifically aimed at applications that require photographic diagnostics with ultra-high speed...

  17. Influence of Blowing of Argon on the Cleanness of Steel

    Directory of Open Access Journals (Sweden)

    A. Pribulová

    2012-09-01

    Full Text Available The mechanical properties of steel components are controlled by the chemical composition and mechanical treatment to which thesteel is submitted. Non-metallic inclusions have a very high influence on the steel quality but secondary metallurgy enables to reduce their content in the steel. Possibilities of secondary metallurgy are relatively extensive but financial situation in Slovak foundries does not enable to make investments in secondary metallurgy in the near future. Accessible means for influencing of steel quality is injection of an inert gas .Main goal of experiments described in the article was verify the influence of blowing of argon into the steel in an electric inductionfurnace on its cleanness. Duration and flow-rate of argon blowing have a very clearly influence on the final content of non-metallicinclusions. Minimum time of argon blowing necessary for reducing of content of non-metallic inclusions in one tonne electric inductionfurnace was more then 6 minutes and recommended argon flow rate was 10 litters per minute.

  18. LArGe. A liquid argon scintillation veto for GERDA

    Energy Technology Data Exchange (ETDEWEB)

    Heisel, Mark

    2011-04-13

    LArGe is a GERDA low-background test facility to study novel background suppression methods in a low-background environment, for possible applications in the GERDA experiment. GERDA searches for the neutrinoless double-beta decay in {sup 76}Ge, by operating naked germanium detectors submersed into 65 m{sup 3} of liquid argon. Similarly, LArGe runs Ge-detectors in 1 m{sup 3} (1.4 tons) of liquid argon, which in addition is instrumented with photomultipliers to detect argon scintillation light. The light is used in anti-coincidence with the germanium detectors, to effectively suppress background events that deposit energy in the liquid argon. This work adresses the design, construction, and commissioning of LArGe. The background suppression efficiency has been studied in combination with a pulse shape discrimination (PSD) technique for various sources, which represent characteristic backgrounds to GERDA. Suppression factors of a few times 10{sup 3} have been achieved. First background data of LArGe (without PSD) yield a background index of (0.12-4.6).10{sup -2} cts/(keV.kg.y) (90% c.l.), which is at the level of the Gerda phase I design goal. Furthermore, for the first time we measure the natural {sup 42}Ar abundance (in parallel to Gerda), and have indication for the 2{nu}{beta}{beta}-decay in natural germanium. (orig.)

  19. Study of Liquid Argon Dopants for LHC Hadron Calorimetry

    CERN Multimedia

    2002-01-01

    Hadron calorimetry based on the Liquid Argon Ionisation Chamber technique is one of the choice techniques for LHC-experimentation. A systematic study of the effect of selected dopants on Liquid Argon (LAr) will be carried out with the aim to achieve an improvement on: \\item (i)~``Fast Liquid Argon'' search and study of dopants to increase the drift velocity. It has been already shown that CH&sub4. added at a fraction of one percent increases the drift velocity by a factor of two or more. \\item (ii)~``Compensated Liquid Argon'' search and study of dopants to increase the response to densely ionising particles, resulting in improved compensation, such as photosensitive dopants. \\end{enumerate}\\\\ \\\\ Monitoring of the parameters involved in understanding the response of a calorimeter is essential. In case of doped LAr, the charge yield, the non-saturated drift velocity and the electron lifetime in the liquid should be precisely and simultaneously monitored as they all vary with the level of dopant concentrati...

  20. Optical emission spectroscopy of argon and hydrogen-containing plasmas

    Science.gov (United States)

    Siepa, Sarah; Danko, Stephan; Tsankov, Tsanko V.; Mussenbrock, Thomas; Czarnetzki, Uwe

    2015-09-01

    Optical emission spectroscopy (OES) on neutral argon is applied to investigate argon, hydrogen and hydrogen-silane plasmas. The spectra are analyzed using an extensive collisional-radiative model (CRM), from which the electron density and the electron temperature (or mean energy) can be calculated. The CRM also yields insight into the importance of different excited species and kinetic processes. The OES measurements are performed on pure argon plasmas at intermediate pressure. Besides, hydrogen and hydrogen-silane plasmas are investigated using argon as a trace gas. Especially for the gas mixture discharges, CRMs for low and high pressure differ substantially. The commonly used line-ratio technique is found to lose its sensitivity for gas mixture discharges at higher pressure. A solution using absolutely calibrated line intensities is proposed. The effect of radiation trapping and the shape of the electron energy distribution function on the results are discussed in detail, as they have been found to significantly influence the results. This work was supported by the Ruhr University Research School PLUS, funded by Germany's Excellence Initiative [DFG GSC 98/3].

  1. Pressure broadening of acetylene rotational Raman lines by argon

    OpenAIRE

    Ceruti, M; Frenkel, D.; Mctaque, J.P.

    1980-01-01

    The anisotropic interaction between acetylene and argon has been studied by observing the density dependence of the acetylene pure rotational Raman line broadening. The observed cross sections are approximately twice that predicted from the known polarizabilities and acetylene molecular quadrupole moment. An empirical atom-atom anisotropic potential adequately parametrizes the results.

  2. Pressure broadening of acetylene rotational Raman lines by argon

    NARCIS (Netherlands)

    Ceruti, M.; Frenkel, D.; McTaque, J.P.

    1980-01-01

    The anisotropic interaction between acetylene and argon has been studied by observing the density dependence of the acetylene pure rotational Raman line broadening. The observed cross sections are approximately twice that predicted from the known polarizabilities and acetylene molecular quadrupole m

  3. Attenuation of vacuum ultraviolet light in pure and xenon-doped liquid argon - an approach to an assignment of the near-infrared emission from the mixture

    CERN Document Server

    Neumeier, A; Himpsl, A; Oberauer, L; Potzel, W; Schönert, S; Ulrich, A

    2015-01-01

    Results of transmission experiments of vacuum ultraviolet light through a 11.6 cm long cell filled with pure and xenon-doped liquid argon are described. Pure liquid argon shows no attenuation down to the experimental short-wavelength cut-off at 118nm. Based on a conservative approach, a lower limit of 1.10 m for the attenuation length of its own scintillation light could be derived. Adding xenon to liquid argon at concentrations on the order of parts per million leads to strong xenon-related absorption features which are used for a tentative assignment of the recently found near-infrared emission observed in electron-beam excited liquid argon-xenon mixtures. Two of the three absorption features can be explained by perturbed xenon transitions and the third one by a trapped exciton (Wannier-Mott) impurity state. A calibration curve connecting the equivalent width of the absorption line at 140 nm with xenon concentration is provided.

  4. 21 CFR 874.4490 - Argon laser for otology, rhinology, and laryngology.

    Science.gov (United States)

    2010-04-01

    ... 21 Food and Drugs 8 2010-04-01 2010-04-01 false Argon laser for otology, rhinology, and laryngology. 874.4490 Section 874.4490 Food and Drugs FOOD AND DRUG ADMINISTRATION, DEPARTMENT OF HEALTH AND... Argon laser for otology, rhinology, and laryngology. (a) Identification. The argon laser device for...

  5. Attach importance to the early diagnosis and treatment of acute coagulation dysfunction after major war trauma

    OpenAIRE

    Li, Jie-Shou; You-sheng LI

    2013-01-01

    Coagulation dysfunction after major war trauma is conventionally attributed to consumption and dilution of coagulation factors. However, recent studies have identified an acute coagulation dysfunction at the early stage after trauma. This coagulation dysfunction due to endogenous coagulation disturbance at the early stage after trauma is called acute traumatic coagulation dysfunction (ATCD), and the patients with ATCD would have an increased complication rate and mortality. Standard coagulati...

  6. Conversion of an atomic to a molecular argon ion and low pressure argon relaxation

    Science.gov (United States)

    M, N. Stankov; A, P. Jovanović; V, Lj Marković; S, N. Stamenković

    2016-01-01

    The dominant process in relaxation of DC glow discharge between two plane parallel electrodes in argon at pressure 200 Pa is analyzed by measuring the breakdown time delay and by analytical and numerical models. By using the approximate analytical model it is found that the relaxation in a range from 20 to 60 ms in afterglow is dominated by ions, produced by atomic-to-molecular conversion of Ar+ ions in the first several milliseconds after the cessation of the discharge. This conversion is confirmed by the presence of double-Gaussian distribution for the formative time delay, as well as conversion maxima in a set of memory curves measured in different conditions. Finally, the numerical one-dimensional (1D) model for determining the number densities of dominant particles in stationary DC glow discharge and two-dimensional (2D) model for the relaxation are used to confirm the previous assumptions and to determine the corresponding collision and transport coefficients of dominant species and processes. Project supported by the Ministry of Education, Science and Technological Development of the Republic of Serbia (Grant No. ON171025).

  7. Nanoparticle assisted coagulation of aqueous alumina suspensions

    Directory of Open Access Journals (Sweden)

    Abdullah Fatih Çetinel

    2012-02-01

    Full Text Available Colloidal processing of ceramics offers a high potential to achieve homogeneous microstructures with improved material properties. In this study, a novel forming method is investigated, which was already applied successfully for the fabrication of ceramic matrix composites (CMC, but is also considered to be a suitable direct casting technique for the fabrication of advanced ceramics with tailored microstructure and properties. The so-called nanoparticle assisted coagulation method (NPAC represents a modification of the hydrolysis-assisted solidification (HAS technique. It promises green components with high green strength, uniform density as well as homogeneous and tailored microstructure. Electrostatically stabilized colloidal suspensions with high solid loadings were produced by dispersing various fractions of submicron alumina powder and aluminium hydroxide nano-powder in water without use of any organic binder. Rheology and coagulation kinetics of suspensions and green part properties were studied regarding to modifications of pH value, setting temperature, amount of setting agent, amount of nano-powder, solids loading and process parameters like ultrasound treatment. It could be revealed that the homogeneous core-shell arrangement of submicron and nanoparticles in the colloidal state can be transmitted to the green state, which improves the microstructure and green density of the green parts. For this, the NPAC method is seen as a promising technique for the fabrication of advanced ceramics with tailored microstructure and properties.

  8. Coagulation mechanisms--nano- and microprocesses.

    Science.gov (United States)

    Licsko, I

    2004-01-01

    Possible coagulation mechanisms were studied in relatively high alkalinity model systems and surface waters. On the basis of available information, original laboratory experiments and simple calculation were performed in order to show that the adsorption of Al3+ and Fe3+ ions is not the dominant process in decreasing the stability of suspended particles. The ions of the feeding coagulants hydrolyse within short time and form positively charged water soluble aluminium- or ferric hydroxides. Adsorption of these water soluble hydroxides onto the surface of colloids and quasi-colloid particles are restricted because of the quick completion of the hydrolysis process in relatively high alkalinity (>1.2 mmol/L) water. The result of complete hydrolysis of Al3+ or Fe3+ ions are slightly positively charged poorly water soluble aluminium or ferric hydroxide sols. The positively charged hydroxides and the associated water molecules are connected to each other by hydrogen bonds, providing a stabile structure. The hydrogen bonds provide the aggregation of slightly positively charged sol aggregation into flocs. Considering the repulsing forces among the sols, high numbers of individual sol particles (having nm sizes) are able adsorb onto the surface of suspended particles, changing their electrical charge and decreasing the stability of the colloids and quasi-colloid particles. This process is dominant in the destabilisation of suspended particles.

  9. Perioperative coagulation management--fresh frozen plasma.

    Science.gov (United States)

    Kor, Daryl J; Stubbs, James R; Gajic, Ognjen

    2010-03-01

    Clinical studies support the use of perioperative fresh frozen plasma (FFP) in patients who are actively bleeding with multiple coagulation factor deficiencies and for the prevention of dilutional coagulopathy in patients with major trauma and/or massive haemorrhage. In these settings, current FFP dosing recommendations may be inadequate. However, a substantial proportion of FFP is transfused in non-bleeding patients with mild elevations in coagulation screening tests. This practice is not supported by the literature, is unlikely to be of benefit and unnecessarily exposes patients to the risks of FFP. The role of FFP in reversing the effects of warfarin anticoagulation is dependent on the clinical context and availability of alternative agents. Although FFP is commonly transfused in patients with liver disease, this practice needs broad reconsideration. Adverse effects of FFP include febrile and allergic reactions, transfusion-associated circulatory overload and transfusion-related acute lung injury. The latter is the most serious complication, being less common with the preferential use of non-alloimmunised, male-donor predominant plasma. FP24 and thawed plasma are alternatives to FFP with similar indications for administration. Both provide an opportunity for increasing the safe plasma donor pool. Although prothrombin complex concentrates and factor VIIa may be used as alternatives to FFP in a variety of specific clinical contexts, additional study is needed.

  10. Monte Carlo models of dust coagulation

    CERN Document Server

    Zsom, Andras

    2010-01-01

    The thesis deals with the first stage of planet formation, namely dust coagulation from micron to millimeter sizes in circumstellar disks. For the first time, we collect and compile the recent laboratory experiments on dust aggregates into a collision model that can be implemented into dust coagulation models. We put this model into a Monte Carlo code that uses representative particles to simulate dust evolution. Simulations are performed using three different disk models in a local box (0D) located at 1 AU distance from the central star. We find that the dust evolution does not follow the previously assumed growth-fragmentation cycle, but growth is halted by bouncing before the fragmentation regime is reached. We call this the bouncing barrier which is an additional obstacle during the already complex formation process of planetesimals. The absence of the growth-fragmentation cycle and the halted growth has two important consequences for planet formation. 1) It is observed that disk atmospheres are dusty thr...

  11. Development of a Silicon Carbide Molecular Beam Nozzle for Simulation Planetary Flybys and Low-Earth Orbit

    Science.gov (United States)

    Patrick, E. L.; Earle, G. D.; Kasprzak, W. T.; Mahaffy, Paul R.

    2008-01-01

    From commercial origins as a molybdenum molecular beam nozzle, a ceramic nozzle of silicon carbide (SiC) was developed for space environment simulation. The nozzle is mechanically stable under extreme conditions of temperature and pressure. A heated, continuous, supersonically-expanded hydrogen beam with a 1% argon seed produced an argon beam component of nearly 4 km/s, with an argon flux exceeding 1x1014 /cm2.s. This nozzle was part of a molecular beam machine used in the Atmospheric Experiments Branch at NASA Goddard Space Flight Center to characterize the performance of the University of Texas at Dallas Ram Wind Sensor (RWS) aboard the Air Force Communications/Navigation Outage Forecasting System (C/NOFS) launched in the Spring of 2008.

  12. Argon metastable dynamics and lifetimes in a direct current microdischarge

    Science.gov (United States)

    Stefanović, Ilija; Kuschel, Thomas; Schröter, Sandra; Böke, Marc

    2014-09-01

    In this paper we study the properties of a pulsed dc microdischarge with the continuous flow of argon. Argon metastable lifetimes are measured by tunable diode laser absorption spectroscopy (TDLAS) and are compared with calculated values which yield information about excitation and de-excitation processes. By increasing the gas flow-rate about 5 times from 10 to 50 sccm, the Arm lifetime increases from 1 to 5 μs due to the reduction of metastable quenching with gas impurities. Optical emission spectroscopy reveals nitrogen and water molecules as the main gas impurities. The estimated N2 density [N2] = 0.1% is too low to explain the measured metastable lifetimes. Water impurity was found to be the main de-excitation source of argon metastable atoms due to high quenching coefficients. The water impurity level of [H2O] = 0.15% to 1% is sufficient to bring calculated metastable lifetimes in line with experiments. The maximum value of water content in the discharge compared to the argon atoms is estimated to approximately 6%, due to the large surface to volume ratio of the microdischarge. The current pulse releases the water molecules from the electrode surface and they are either re-adsorbed in the time between 0.4 ms for [H2O] = 1% and 2.6 ms for [H2O] = 0.15% or pumped out of the discharge with the speed equal to the gas flow-rate. Depending on its partial pressure, the water impurity re-adsorption time is of the order of magnitude or less then the argon gas residence time.

  13. Argon metastable dynamics and lifetimes in a direct current microdischarge

    Energy Technology Data Exchange (ETDEWEB)

    Stefanović, Ilija [Institute of Physics, University of Belgrade, Pregrevica 118, 11080 Belgrade (Serbia); Kuschel, Thomas; Schröter, Sandra; Böke, Marc [Ruhr-Universität Bochum, Institute for Experimental Physics II, Universitätsstraße 150, 44780 Bochum (Germany)

    2014-09-21

    In this paper we study the properties of a pulsed dc microdischarge with the continuous flow of argon. Argon metastable lifetimes are measured by tunable diode laser absorption spectroscopy (TDLAS) and are compared with calculated values which yield information about excitation and de-excitation processes. By increasing the gas flow-rate about 5 times from 10 to 50 sccm, the Ar{sup m} lifetime increases from 1 to 5 μs due to the reduction of metastable quenching with gas impurities. Optical emission spectroscopy reveals nitrogen and water molecules as the main gas impurities. The estimated N₂ density [N₂]=0.1% is too low to explain the measured metastable lifetimes. Water impurity was found to be the main de-excitation source of argon metastable atoms due to high quenching coefficients. The water impurity level of [H₂O]=0.15% to 1% is sufficient to bring calculated metastable lifetimes in line with experiments. The maximum value of water content in the discharge compared to the argon atoms is estimated to approximately 6%, due to the large surface to volume ratio of the microdischarge. The current pulse releases the water molecules from the electrode surface and they are either re-adsorbed in the time between 0.4 ms for [H₂O]=1% and 2.6 ms for [H₂O]=0.15% or pumped out of the discharge with the speed equal to the gas flow-rate. Depending on its partial pressure, the water impurity re-adsorption time is of the order of magnitude or less then the argon gas residence time.

  14. Disinfection of an infrared coagulation device used to treat hemorrhoids.

    Science.gov (United States)

    Rutala, William A; Gergen, Maria F; Weber, David J

    2012-02-01

    Infrared coagulation devices are used to treat internal hemorrhoids, and as semicritical items should undergo high-level disinfection between patients. We developed and validated a method for disinfecting an infrared coagulation device that cannot be immersed in disinfectant solution.

  15. Analysis and optimization of coagulation and flocculation process

    Science.gov (United States)

    Saritha, V.; Srinivas, N.; Srikanth Vuppala, N. V.

    2015-02-01

    Natural coagulants have been the focus of research of many investigators through the last decade owing to the problems caused by the chemical coagulants. Optimization of process parameters is vital for the effectiveness of coagulation process. In the present study optimization of parameters like pH, dose of coagulant and mixing speed were studied using natural coagulants sago and chitin in comparison with alum. Jar test apparatus was used to perform the coagulation. The results showed that the removal of turbidity was up to 99 % by both alum and chitin at lower doses of coagulant, i.e., 0.1-0.3 g/L, whereas sago has shown a reduction of 70-100 % at doses of 0.1 and 0.2 g/L. The optimum conditions observed for sago were 6 and 7 whereas chitin was stable at all pH ranges, lower coagulant doses, i.e., 0.1-0.3 g/L and mixing speed—rapid mixing at 100 rpm for 10 min and slow mixing 20 rpm for 20 min. Hence, it can be concluded that sago and chitin can be used for treating water even with large seasonal variation in turbidity.

  16. Genetic parameters for milk coagulation properties in Estonian Holstein cows.

    NARCIS (Netherlands)

    Vallas, M.; Bovenhuis, H.; Kaart, T.; Parna, K.; Kiiman, H.

    2010-01-01

    The objective of this study was to estimate heritabilities and repeatabilities for milk coagulation traits [milk coagulation time (RCT) and curd firmness (E30)] and genetic and phenotypic correlations between milk yield and composition traits (milk fat percentage and protein percentage, urea, somati

  17. Influence of blood flow on the coagulation cascade

    DEFF Research Database (Denmark)

    The influence of diffusion and convetive flows on the blood coagulation cascade is investigated for a controlled perfusion experiment. We present a cartoon model and reaction schemes for parts of the coagulation cascade with sunsequent set up of a mathematical model in two space dimensions plus one...

  18. Coagulation chemistries for silica removal from cooling tower water.

    Energy Technology Data Exchange (ETDEWEB)

    Nyman, May Devan; Altman, Susan Jeanne; Stewart, Tom

    2010-02-01

    The formation of silica scale is a problem for thermoelectric power generating facilities, and this study investigated the potential for removal of silica by means of chemical coagulation from source water before it is subjected to mineral concentration in cooling towers. In Phase I, a screening of many typical as well as novel coagulants was carried out using concentrated cooling tower water, with and without flocculation aids, at concentrations typical for water purification with limited results. In Phase II, it was decided that treatment of source or make up water was more appropriate, and that higher dosing with coagulants delivered promising results. In fact, the less exotic coagulants proved to be more efficacious for reasons not yet fully determined. Some analysis was made of the molecular nature of the precipitated floc, which may aid in process improvements. In Phase III, more detailed study of process conditions for aluminum chloride coagulation was undertaken. Lime-soda water softening and the precipitation of magnesium hydroxide were shown to be too limited in terms of effectiveness, speed, and energy consumption to be considered further for the present application. In Phase IV, sodium aluminate emerged as an effective coagulant for silica, and the most attractive of those tested to date because of its availability, ease of use, and low requirement for additional chemicals. Some process optimization was performed for coagulant concentration and operational pH. It is concluded that silica coagulation with simple aluminum-based agents is effective, simple, and compatible with other industrial processes.

  19. Characteristics of particle coagulation in an underground parking lot.

    Science.gov (United States)

    Zhao, Yu; Kato, Shinsuke; Zhao, Jianing

    2015-12-01

    Particles in vehicle exhaust plumes in underground parking lots have adverse health effects due to the enclosed environment in which they are released and the temperature difference between the tailpipe and ambient environment; at the same time, particle coagulation might be obvious near the tailpipe in an underground parking lot. In the present study, airflow and temperature fields were calculated using the Realizable k-ε model, and the Eulerian particle transport model was selected in the numerical simulation of particle concentration dispersion. Polydisperse thermal coagulation due to Brownian collisions was employed to calculate the particle coagulation. The results show that particle coagulation rate and half-time were significant within 1 m from the tailpipe. The variations in the particle coagulation rate and half-time were similar, but their directions were opposite. Air exhaust time was nearly four times longer than averaged half-time and 40 times longer than minimum half-time. The peak particle diameter increased approximately 1.43 times due to coagulation. A double particle concentration at the tailpipe caused the fourfold rise in the particle coagulation rate in the distance ranging less than 1 m from the tailpipe. An increase in exhaust velocity at the tailpipe could shorten the obvious range of particle coagulation along the centerline of the tailpipe from 1 to 0.8 m in the study.

  20. Critical assessment of chitosan as coagulant to remove cyanobacteria

    NARCIS (Netherlands)

    Lurling, Miguel; Noyma, Natalia Pessoa; Magalhães, de Leonardo; Miranda, Marcela; Mucci, Maíra; Oosterhout, van F.; Huszar, Vera L.M.; Marinho, Marcelo Manzi

    2017-01-01

    Removal of cyanobacteria from the water column using a coagulant and a ballast compound is a promising technique to mitigate nuisance. As coagulant the organic, biodegradable polymer chitosan has been promoted. Results in this study show that elevated pH, as may be common during cyanobacterial

  1. Critical assessment of chitosan as coagulant to remove cyanobacteria

    NARCIS (Netherlands)

    Lürling, Miquel; Noyma, Natalia Pessoa; Magalhães, Leonardo de; Miranda, Marcela; Mucci, Maíra; Oosterhout, Frank van; Huszar, Vera L.M.; Marinho, Marcelo Manzi

    2017-01-01

    Removal of cyanobacteria from the water column using a coagulant and a ballast compound is a promising technique to mitigate nuisance. As coagulant the organic, biodegradable polymer chitosan has been promoted. Results in this study show that elevated pH, as may be common during cyanobacterial

  2. A NEW TECHNIQUE FOR PURIFICATION OF WATER USING NATURAL COAGULANT

    Directory of Open Access Journals (Sweden)

    C. P. Pise

    2014-12-01

    Full Text Available The use of chemical coagulants is not suitable due to health and economic considerations. Studies are carried out in laboratory scale on deionized and river water containing synthetic turbidity of kaolinite. Experiments are carried out in three turbidity ranges: 150, 450, 1000 (NTU and the pH range 6-8. The efficiency of Moringa oleifera (MO seed extract and alum is examined with jar test, settling column and pilot test. The aim of this study is to find out the optimum combination of MO and alum using alum as a coagulant aid in household treatment of natural river surface water for domestic use. The various coagulant combinations with which the raw water from the river is treated include Moringa oleifera seed powder only, Alum coagulant only and blended Moringa oleifera seeds and alum in different combinations. When Moringa oleifera seed powder is used as the sole coagulant, a filter was needed to obtain an acceptable turbidity value but there was no need for pH adjustment or correction. Moringa oleifera seed powder can be used in treating household drinking water either as a sole coagulant or in combination with alum as a coagulant aid. The recommended ratio for the combined coagulant dose is 60% MO seed powder and 40% alum.

  3. Metals in airpollution particles decrease whole blood coagulation time

    Science.gov (United States)

    The mechanism underlying the pro-coagulative effect of air pollution particle exposure is not known. We tested the postulate that 1) the soluble fraction ofan air pollution particle can affect whole blood coagulation time and 2) metals included in the soluble fraction are respons...

  4. Pre-coagulation for microfiltration of an upland surface water.

    Science.gov (United States)

    Pikkarainen, A T; Judd, S J; Jokela, J; Gillberg, L

    2004-01-01

    The effect of different coagulants on cake formation and hydraulic resistance in membrane filtration of strongly coloured (SUVA> or =4.8) upland surface water has been studied at bench-scale under constant pressure conditions. Coagulants used were aluminium sulphate, polyaluminium chloride, ferric chloride and ferric sulphate. Optimisation of coagulation parameters was carried by conventional jar testing. The R'c (specific cake resistance in m(-2)) values were determined for all coagulants over a range of coagulant doses and slow mixing flocculation periods. Experiments indicated slight differences in cake formation trends between ferric- and aluminium-based coagulants and chloride and sulphate counterions, but that the range of measured R'c values was small (0.9 and 2.6 x 10(18) m(-2)) over the range of doses studied. Greater than 99% UV(254) removal was achieved with every coagulant, whereas dissolved organic carbon (DOC) removal ranged from 78% to 88%. Optimisation of the pre-coagulation-membrane filtration process suggests ferric chloride to be slightly superior for the feedwater matrix studied on the basis of DOC removal, whereas ferric sulphate gave slightly lower filter cake specific resistance values.

  5. On-line experimental results of an argon gas cell-based laser ion source (KEK Isotope Separation System)

    Science.gov (United States)

    Hirayama, Y.; Watanabe, Y. X.; Imai, N.; Ishiyama, H.; Jeong, S. C.; Jung, H. S.; Miyatake, H.; Oyaizu, M.; Kimura, S.; Mukai, M.; Kim, Y. H.; Sonoda, T.; Wada, M.; Huyse, M.; Kudryavtsev, Yu.; Van Duppen, P.

    2016-06-01

    KEK Isotope Separation System (KISS) has been developed at RIKEN to produce neutron rich isotopes with N = 126 to study the β -decay properties for application to astrophysics. The KISS is an element-selective mass-separation system which consists of an argon gas cell-based on laser ion source for atomic number selection and an ISOL mass-separation system. The argon gas cell of KISS is a key component to stop and collect the unstable nuclei produced in a multi-nucleon transfer reaction, where the isotopes of interest will be selectively ionized using laser resonance ionization. We have performed off- and on-line experiments to study the basic properties of the gas cell as well as of the KISS. We successfully extracted the laser-ionized stable 56Fe (direct implantation of a 56Fe beam into the gas cell) atoms and 198Pt (emitted from the 198Pt target by elastic scattering with a 136Xe beam) atoms from the KISS during the commissioning on-line experiments. We furthermore extracted laser-ionized unstable 199Pt atoms and confirmed that the measured half-life was in good agreement with the reported value.

  6. Disseminated intravascular coagulation in term and preterm neonates.

    Science.gov (United States)

    Veldman, Alex; Fischer, Doris; Nold, Marcel F; Wong, Flora Y

    2010-06-01

    Among critically ill patients, the risk of developing disseminated intravascular coagulation (DIC) is probably highest in neonates. Low plasma reserves in pro- and anticoagulant coagulation factors, intravascular volume contraction after birth, and a high incidence of hypoxia and sepsis in critically ill newborns rapidly lead to a decompensation of the coagulation system in this population. Global coagulation tests and single-factor plasma levels have to be interpreted in the context of age-corrected normal ranges. Platelet consumption and reduced protein C plasma levels have diagnostic value; the latter also has prognostic potential in neonates with DIC and sepsis. Therapeutic success relies heavily on reversal of the underlying condition. Some coagulation-specific therapies have been explored in small studies and case series with varying success and sometimes conflicting results. Therefore, larger controlled trials in this common and serious condition are urgently needed.

  7. Coagulation defects resulting from ambient temperature-induced hypothermia.

    Science.gov (United States)

    Staab, D B; Sorensen, V J; Fath, J J; Raman, S B; Horst, H M; Obeid, F N

    1994-05-01

    Ambient temperature-induced hypothermia noted in trauma patients is frequently accompanied by a bleeding diathesis despite "laboratory normal" coagulation values. To document this impression, the following experiment was conducted. Coagulation studies and platelet function studies were performed in ten minipigs during induced whole body hypothermia (40 degrees C to 34 degrees C) and rewarming. Cooling was achieved in 2 to 3 hours and rewarming took 4 to 5 hours. In addition, similar coagulation and platelet function studies were conducted on plasma samples from the same animals that were cooled and then rewarmed in a water bath. Platelet counts and function as measured by Sonoclot analysis and aggregation did not decrease significantly with hypothermia in either model. Plasma cooled in a water bath demonstrated abnormal PT and aPTT (p coagulation defects in a porcine model. Some of the coagulation defects were most pronounced during rewarming.

  8. Performance and characterization of a new tannin-based coagulant

    Science.gov (United States)

    Beltrán-Heredia, J.; Sánchez-Martín, J.; Gómez-Muñoz, C.

    2012-09-01

    Diethanolamine and formaldehyde were employed to cationize tannins from black wattle. This novel coagulant called CDF was functionally characterized in removing sodium dodecylbenzene sulfonate (anionic surfactant) and Palatine Fast Black WAN (azoic dye). Refined tannin-derived commercial coagulants exhibited similar efficiency, while CDF presented higher coagulant ability than alum, a usual coagulant agent. Low doses of CDF (ca. 100 mg L-1) were able to remove more than 70 % of surfactant and more than 85 % of dye (initial pollutant concentration of ca. 100 mg L-1) and it presented no temperature affection and worked at a relatively wide pH range. Surfactant and dye removal responded to the classical coagulant-and-adsorption models, such as Frumkin-Fowler-Guggenheim or Gu and Zhu in the case of surfactant, and Langmuir and Freundlich in the case of dye.

  9. Clinical and prognostic significance of coagulation assays in lung cancer.

    Science.gov (United States)

    Tas, Faruk; Kilic, Leyla; Serilmez, Murat; Keskin, Serkan; Sen, Fatma; Duranyildiz, Derya

    2013-03-01

    Activation of coagulation and fibrinolysis is frequently encountered among cancer patients. Such tumors are supposed to be associated with higher risk of invasion, metastases and eventually worse outcome. The aim of this study is to explore the prognostic value of blood coagulation tests for lung cancer patients. The study comprised 110 lung cancer patients. Pretreatment blood coagulation tests including PT, aPTT, PTA, INR, D-dimer, fibrinogen levels and platelet counts were evaluated. The plasma level of all coagulation tests revealed statistically significant difference between patient and control group (p coagulation parameters (p = 0.05). In conclusion, elevation of PT and INR are associated with decreased survival in lung cancer patients.

  10. Plasma diagnostics of the SIMPA Ecr ion source by X-ray spectroscopy, Collisions of H-like Neon ions with Argon clusters; Diagnostic du plasma de la source d'ions ECR SIMPA par spectroscopie X, Collision d'ions neon hydrogenoides avec des agregats d'argon

    Energy Technology Data Exchange (ETDEWEB)

    Adrouche, N

    2006-09-15

    The first part of this thesis is devoted to the SIMPA ECR ion source characterization, first, I explored the ion source's capacities on the point of view of extracted currents for three elements, argon, krypton and neon. By analyzing the Bremsstrahlung spectra, I determined the electronic temperature in the plasma and the electronic and ionic densities. In a second time, I recorded high resolution X-spectra of argon and krypton plasma's. By taking into account the principal mechanisms of production of a K hole in the ions inside the plasma, I determined the ionic densities of the high charge states of argon. Lastly, I highlighted a correlation between the ions charge states densities with the intensities of extracted currents. The second part of the thesis is devoted to Ne{sup 9+-} argon clusters collisions. First, I presented simple and effective theoretical models allowing to describe the phenomena occurring during a collision, from the point of view of the projectile. I carried out a simulation for a collision of an ion Ne{sup 9+} with an argon cluster of a given size, which has enabled us to know the energy levels populated during the electronic capture and to follow the number of electrons in each projectile shell. Lastly, I presented the first results of a collision between a Ne{sup 9+} beam and argon clusters. These results, have enabled me by using projectile X-ray spectroscopy during the ions-clusters collision, to evidence a strong clustering of targets atoms and to highlight an electronic multi-capture in the projectile ion excited states. (author)

  11. Myocardial Dose Response To Argon Laser Irradiation In Saline And Blood With Ultramicroscopical Analysis Of Myocardial Debris

    Science.gov (United States)

    Ben-Shachar, Giora; Morse, Dennis E.; Sivakoff, Mark C.; Riemenschneider, Thomas A.

    1986-01-01

    Fresh myocardial segments from fetal and adult sheep, and from newborn and adult pigs were exposed to continuous mode argon laser irradiation in saline medium. Additionally, myocardial segments from newborn pigs were exposed to laser irradiation in fresh, heparin-ized blood medium. The irradiation distance from the tip of the quartz fiber to the tissue varied between contact and 20 mm, and power output at the fiber tip varied between 1 and 8 watts. Exposure time was kept constant at 2 seconds. Tissue debris was also processed for study by scanning and transmission electron microscopy. There was no difference in myocardial tissue response between sheep and pigs, nor was there a difference in response between young and adult animals. In both saline and blood media, there was a sharp decrease in burn depth with increasing irradiation distance. With increasing irradiation distances in saline medium, burn diameter increased initially and then plateaued; while with increasing irradiation distance in blood medium, the burn diameter decreased sharply. When the fiber tip was in contact with the tissue, the diameter of burn was greater in blood than saline, while the depth of burn was similar. Filtration of the tissue bath demonstrated particles as large as 3 mm in length which were composed of deformed and coagulated whole tissue segments. Electron and scanning micrography of the bath media identified intracellular components and fragments of burst cells. In conclusion, we have found no difference in adult vs. newborn, or sheep vs. porcine myocardial response to fiberoptic argon laser irradiation. The most critical factors affecting width and depth of burn were the distance of the fiber tip from the tissue, and the medium in which the tissue was bathed. Of particular clinical importance was the fact that the burn width and depth drastically decreased when blood was present between the laser fiber and the tissue.

  12. Coagulant recovery and reuse for drinking water treatment.

    Science.gov (United States)

    Keeley, James; Jarvis, Peter; Smith, Andrea D; Judd, Simon J

    2016-01-01

    Coagulant recovery and reuse from waterworks sludge has the potential to significantly reduce waste disposal and chemicals usage for water treatment. Drinking water regulations demand purification of recovered coagulant before they can be safely reused, due to the risk of disinfection by-product precursors being recovered from waterworks sludge alongside coagulant metals. While several full-scale separation technologies have proven effective for coagulant purification, none have matched virgin coagulant treatment performance. This study examines the individual and successive separation performance of several novel and existing ferric coagulant recovery purification technologies to attain virgin coagulant purity levels. The new suggested approach of alkali extraction of dissolved organic compounds (DOC) from waterworks sludge prior to acidic solubilisation of ferric coagulants provided the same 14:1 selectivity ratio (874 mg/L Fe vs. 61 mg/L DOC) to the more established size separation using ultrafiltration (1285 mg/L Fe vs. 91 mg/L DOC). Cation exchange Donnan membranes were also examined: while highly selective (2555 mg/L Fe vs. 29 mg/L DOC, 88:1 selectivity), the low pH of the recovered ferric solution impaired subsequent treatment performance. The application of powdered activated carbon (PAC) to ultrafiltration or alkali pre-treated sludge, dosed at 80 mg/mg DOC, reduced recovered ferric DOC contamination to water quality parameters. Several PAC-polished recovered coagulants provided the same or improved DOC and turbidity removal as virgin coagulant, as well as demonstrating the potential to reduce disinfection byproducts and regulated metals to levels comparable to that attained from virgin material.

  13. Electron density and temperature in NIO1 RF source operated in oxygen and argon

    Science.gov (United States)

    Barbisan, M.; Zaniol, B.; Cavenago, M.; Pasqualotto, R.; Serianni, G.; Zanini, M.

    2017-08-01

    The NIO1 experiment, built and operated at Consorzio RFX, hosts an RF negative ion source, from which it is possible to produce a beam of maximum 130 mA in H- ions, accelerated up to 60 kV. For the preliminary tests of the extraction system the source has been operated in oxygen, whose high electronegativity allows to reach useful levels of extracted beam current. The efficiency of negative ions extraction is strongly influenced by the electron density and temperature close to the Plasma Grid, i.e. the grid of the acceleration system which faces the source. To support the tests, these parameters have been measured by means of the Optical Emission Spectroscopy diagnostic. This technique has involved the use of an oxygen-argon mixture to produce the plasma in the source. The intensities of specific Ar I and Ar II lines have been measured along lines of sight close to the Plasma Grid, and have been interpreted with the ADAS package to get the desired information. This work will describe the diagnostic hardware, the analysis method and the measured values of electron density and temperature, as function of the main source parameters (RF power, pressure, bias voltage and magnetic filter field). The main results show that not only electron density but also electron temperature increase with RF power; both decrease with increasing magnetic filter field. Variations of source pressure and plasma grid bias voltage appear to affect only electron temperature and electron density, respectively.

  14. Simulation of nanoparticle coagulation in radio-frequency C2H2/Ar microdischarges

    Science.gov (United States)

    Xiang-Mei, Liu; Qi-Nan, Li; Rui, Li

    2016-06-01

    The nanoparticle coagulation is investigated by using a couple of fluid models and aerosol dynamics model in argon with a 5% molecular acetylene admixture rf microdischarges, with the total input gas flow rate of 400 sccm. It co-exists with a homogeneous, secondary electron-dominated low temperature γ-mode glow discharges. The heat transfer equation and flow equation for neutral gas are taken into account. We mainly focused on investigations of the nanoparticle properties in atmospheric pressure microdischarges, and discussed the influences of pressure, electrode spacing, and applied voltage on the plasma density and nanoparticle density profiles. The results show that the characteristics of microdischarges are quite different from those of low pressure radio-frequency discharges. First, the nanoparticle density in the bulk plasma in microdischarges is much larger than that of low pressure discharges. Second, the nanoparticle density of 10 nm experiences an exponential increase as soon as the applied voltage increases, especially in the presheath. Finally, as the electrode spacing increases, the nanoparticle density decreased instead of increasing. Project supported by the Natural Science Foundation of Heilongjiang Province, China (Grant Nos. A2015011 and A2015010), the Postdoctoral Scientific Research Development Fund of Heilongjiang Province, China (Grant No. LBH-Q14159), the Program for Young Teachers Scientific Research in Qiqihar University (Grant No. 2014k-Z11), the National Natural Science Foundation of China (Grant No. 11404180), and the University Nursing Program for Yong Scholars with Creative Talents in Heilongjiang Province, China (Grant No. UNPYSCT-2015095).

  15. Anemia Due to Inflammation in an Anti-Coagulated Patient with Blue Rubber Bleb Nevus Syndrome.

    Science.gov (United States)

    Bonaventura, Aldo; Liberale, Luca; Hussein El-Dib, Nadia; Montecucco, Fabrizio; Dallegri, Franco

    2016-01-01

    Blue rubber bleb nevus syndrome (BRBNS) is a rare disease characterized by vascular malformations mostly involving skin and gastrointestinal tract. This disease is often associated with sideropenic anemia and occult bleeding. We report the case of chronic severe anemia in an old patient under oral anticoagulation treatment for chronic atrial fibrillation. At admission, the patient also presented fever and increased laboratory parameters of systemic inflammation (ferritin 308 mcg/L, C-reactive protein (CRP) 244 mg/L). A small bluish-colored lesion over the left ear lobe was observed. Fecal occult blood test was negative as well as other signs of active bleeding. Lower gastrointestinal endoscopy revealed internal hemorrhoids and multiple teleangiectasias that were treated with argon plasma coagulation. Videocapsule endoscopy demonstrated multiple bluish nodular lesions in the small intestine. Unexpectedly, chronic severe anemia due to systemic inflammation was diagnosed in an old anticoagulated patient with BRNBS. The patient was treated with blood transfusions, hydration, antibiotic treatment, and long-acting octreotide acetate, without stopping warfarin. Fever and inflammation disappeared without any acute gastrointestinal bleeding and improvement of hemoglobin levels at three-month follow up. This is the oldest patient presenting with chronic anemia, in which BRNBS was also diagnosed. Surprisingly, anemia was mainly caused by systemic inflammation instead of chronic gastrointestinal bleeding. However, we would recommend investigating this disease also in old subjects with mild signs and symptoms.

  16. Evidence for Argon Content in Pure Oxygen from Thermal Data

    Science.gov (United States)

    Steur, Peter P. M.; Yang, Inseok; Pavese, Franco

    2017-02-01

    Since many years it is known that argon impurities in oxygen change the temperature of the oxygen triple point by +12 K{\\cdot }mol^{-1} (positive, while most impurities decrease the temperature) without any effect on the melting range of this transition, for the impurity concentrations usually encountered in nominally pure gases. It has been hypothesized that thermal measurements on the α -β solid-to-solid transition at 23.8 K or the β -γ solid-to-solid transition at 43.8 K may give reliable evidence regarding the argon content. However, such measurements require very long times for full completion of each transition (with prohibitive costs if liquid helium is used) and for the α -β solid-to-solid transition the heat pulse method cannot be applied reliably. The availability of closed-cycle refrigerators permits the first obstacle to be surmounted. The automatic system earlier developed at INRIM during the EU Multicells project and used extensively for the project on the isotopic effect in neon is perfectly suited for such measurements. Thus, the uncertainties of the temperature measurements are similar to those obtained previously (of the order of 0.1 mK or less). Three argon-in-oxygen mixtures were prepared gravimetrically and certified at KRISS, just as was previously done for the work on the neon isotopic compositions. Results of continuous-current measurements on the α -β solid-to-solid transition, along with the triple-point data obtained with the heat pulse method, are presented for one cell with a known doped argon content, to be compared with similar data from a cell with oxygen of very high purity. In addition, some preliminary data for the β -γ solid-to-solid transition are given. The measurements on the mixture with the highest argon content, about 1002 μmol{\\cdot } mol^{-1}, imply a (linear) sensitivity of (116 ± 7) K{\\cdot }mol^{-1} for the α -β transition. This sensitivity may be different at much lower argon contents, and follow

  17. Comparison of coagulants and coagulation aids for treatment of meat processing wastewater by column flotation.

    Science.gov (United States)

    de Sena, Rênnio F; Moreira, Regina F P M; José, Humberto J

    2008-11-01

    The physicochemical treatment of the wastewater from a meat processing industry was studied using three ferric salts as coagulants in conjunction with four different polymers as coagulation aids by batch column flotation. The effluent was characterized in terms of pH (6.5-6.7), turbidity (1000-12000 NTU), total solids (TS) (2300-7000mgl(-1)), oils and greases (OG) (820-1050mgl(-1)), and biochemical and chemical oxygen demands (BOD(5) and COD) (1200-1760 and 2800-3230mgl(-1)), respectively. The treatments achieved typical organic load reductions of oils and greases, and total solids (up to 85%), as well as biochemical and chemical oxygen demands (between 62.0-78.8% and 74.6-79.5%, respectively). The research also found that the utilization of a column flotation achieved high efficiency of organic matter removal and its operation as a primary treatment showed no significant dependence of pollutant removal and air flow rate.

  18. Data Reduction Processes Using FPGA for MicroBooNE Liquid Argon Time Projection Chamber

    Energy Technology Data Exchange (ETDEWEB)

    Wu, Jinyuan

    2010-05-26

    MicroBooNE is a liquid Argon time projection chamber to be built at Fermilab for an accelerator-based neutrino physics experiment and as part of the R&D strategy for a large liquid argon detector at DUSEL. The waveforms of the {approx}9000 sense wires in the chamber are continuously digitized at 2 M samples/s - which results in a large volume of data coming off the TPC. We have developed a lossless data reduction scheme based on Huffman Coding and have tested the scheme on cosmic ray data taken from a small liquid Argon time projection chamber, the BO detector. For sense wire waveforms produced by cosmic ray tracks, the Huffman Coding scheme compresses the data by a factor of approximately 10. The compressed data can be fully recovered back to the original data since the compression is lossless. In addition to accelerator neutrino data, which comes with small duty cycle in sync with the accelerator beam spill, continuous digitized waveforms are to be temporarily stored in the MicroBooNE data-acquisition system for about an hour, long enough for an external alert from possible supernova events. Another scheme, Dynamic Decimation, has been developed to compress further the potential supernova data so that the storage can be implemented within a reasonable budget. In the Dynamic Decimation scheme, data are sampled at the full sampling rate in the regions-of-interest (ROI) containing waveforms of track-hits and are decimated down to lower sampling rate outside the ROI. Note that unlike in typical zerosuppression schemes, in Dynamic Decimation, the data in the pedestal region are not thrown away but kept at a lower sampling rate. An additional factor of 10 compression ratio is achieved using the Dynamic Decimation scheme on the BO detector data, making a total compression rate of approximate 100 when the Dynamic Decimation and the Huffman Coding functional blocks are cascaded. Both of the blocks are compiled in low-cost FPGA and their silicon resource usages are low.

  19. Aluminium metallisation of argon and oxygen plasma-modified polycarbonate thin film surfaces

    Science.gov (United States)

    Rastomjee, C. S.; Keil, M.; Sotobayashi, H.; Bradshaw, A. M.; Lamont, C. L. A.; Gador, D.; Umbach, E.

    1998-12-01

    The influence of plasma treatment on the metallisation of polycarbonate surfaces was studied using X-ray absorption spectroscopy (XAFS) and core level X-ray photoelectron spectroscopy (XPS). Thin films of two different molecules were chosen: bis-phenol-A polycarbonate with phenol endgroups (P-PC) prepared ex situ by the spin-coating technique onto MoTe 2{0001}surfaces, and the model compound bis-phenol-A polycarbonate ( n=1) with tert-butyl phenyl endgroups (tBP-PC) evaporated in situ in UHV onto Cu{110}, Ag{100} and Ag{111} surfaces with film thicknesses of up to several monolayers. Surfaces of untreated samples and of samples which were pre-treated with either an inert argon or a reactive oxygen microwave plasma were metallised with Al (evaporated by electron beam heating) at film thicknesses ranging from the sub-monolayer region up to several monolayers. For the untreated surface, XAFS and XPS spectra suggest that the Al reacts with the carbonate groups leading to a breaking of the CO double bonds (and/or a reduction in bond order) as well as formation of Al oxide, Al hydroxide and Al-O-C linkages. A study of the time-dependent oxidation of the evaporated Al leads to the conclusion that Al slowly diffuses to the reactive sites in the first few subsurface layers of the polymer. Argon plasma treatment of samples leads to a reduction in the number of carbonyl groups in the near surface region. After metal deposition a higher ratio of metallic, non-reacted, Al was observed covering the polycarbonate surface and the diffusion rate into the polymer bulk seems to be higher than in the case of the untreated surface. Oxygen plasma treatment leads to the creation of additional CO containing species which also react with the Al in the subsequent metallisation process. Here, the ratio of oxidised Al on the polymer surface is higher than observed for untreated and argon plasma pre-treated polymer surfaces.

  20. Measurement of scintillation and ionization yield and scintillation pulse shape from nuclear recoils in liquid argon

    Energy Technology Data Exchange (ETDEWEB)

    Cao, H.; Alexander, T.; Aprahamian, A.; Avetisyan, R.; Back, H. O.; Cocco, A. G.; DeJongh, F.; Fiorillo, G.; Galbiati, C.; Grandi, L.; Guardincerri, Y.; Kendziora, C.; Lippincott, W. H.; Love, C.; Lyons, S.; Manenti, L.; Martoff, C. J.; Meng, Y.; Montanari, D.; Mosteiro, P.; Olvitt, D.; Pordes, S.; Qian, H.; Rossi, B.; Saldanha, R.; Sangiorgio, S.; Siegl, K.; Strauss, S. Y.; Tan, W.; Tatarowicz, J.; Walker, S.; Wang, H.; Watson, A. W.; Westerdale, S.; Yoo, J.

    2015-05-01

    We have measured the scintillation and ionization yield of recoiling nuclei in liquid argon as a function of applied electric field by exposing a dual-phase liquid argon time projection chamber (LAr-TPC) to a low energy pulsed narrow band neutron beam produced at the Notre Dame Institute for Structure and Nuclear Astrophysics. Liquid scintillation counters were arranged to detect and identify neutrons scattered in the TPC and to select the energy of the recoiling nuclei. We report measurements of the scintillation yields for nuclear recoils with energies from 10.3 to 57.3 keV and for median applied electric fields from 0 to 970 V / cm . For the ionization yields, we report measurements from 16.9 to 57.3 keV and for electric fields from 96.4 to 486 V / cm . We also report the observation of an anticorrelation between scintillation and ionization from nuclear recoils, which is similar to the anticorrelation between scintillation and ionization from electron recoils. Assuming that the energy loss partitions into excitons and ion pairs from 83 m Kr internal conversion electrons is comparable to that from 207 Bi conversion electrons, we obtained the numbers of excitons ( N ex ) and ion pairs ( N i ) and their ratio ( N ex / N i ) produced by nuclear recoils from 16.9 to 57.3 keV. Motivated by arguments suggesting direction sensitivity in LAr-TPC signals due to columnar recombination, a comparison of the light and charge yield of recoils parallel and perpendicular to the applied electric field is presented for the first time.

  1. Loss of vasoreactivity by laser thermal energy or argon laser irradiation.

    Science.gov (United States)

    Tomaru, T; Uchida, Y; Nakamura, F; Miwa, A Y; Kawai, S; Okada, R; Sugimoto, T

    1993-05-01

    Vasoreactivity of laser-treated vessels was investigated in two different experimental conditions. The canine left circumflex coronary artery (LCx) was lased under perfusion with Krebs-bicarbonate buffer by means of a thermal laser (hot-tip probe, HT) at 7 W for 6 seconds and an argon laser beam through a 300 microns optical fiber at 3 W (tip power) for 1 second at 12 spots. A nontreated segment of the LCx served as a control. Two 3-mm long segments were obtained from the treated segment: one to measure the results of potassium (K) induced contraction, and another 3, 4 diaminopyridine (DAP; K channel inhibitor) induced contraction. In 11 instances, coronary angiography of the perfused artery showed less than 50% stenosis after laser treatment. The segments were then mounted isometrically with 1 g tension in Krebs-bicarbonate buffer. Contraction was induced either with 30 mM KCI or 10(-2) M DAP and expressed as developed tension (gram; g). KCI induced vasocontraction of 4.15 +/- 0.93 g in the control, 0.33 +/- 0.71 g in laser irradiated segments (P thermally-treated segments (P thermally treated segments (P dilatation reduced the stenosis to less than 50%. The lesions also showed reduced vasoreactivity. In vivo thermal angioplasty resulted in reduced vasoreactivity compared to control in 4 anesthetized dogs. Thus, laser and thermal angioplasty reduced vasoreactivity induced by either KCI or 3, 4 DAP. Neither acetylcholine at 10(-6) M nor papaverine at 10(-4) M was able to induce relaxation of treated segments. In conclusion, 1) the lased coronary artery loses its vasoreactivity to either a constrictive or relaxing agent, 2) although stenosis may be produced by laser energy, additional balloon dilatation can reduce residual stenosis, and 3) laser thermal or argon laser angioplasty may prevent severe coronary spasm.

  2. MicroBooNE and the Road to Large Liquid Argon Neutrino Detectors

    Science.gov (United States)

    Karagiorgi, G.

    Liquid Argon Time Projection Chambers (LArTPC's) provide a promising technology for multi-kiloton scale detectors aiming to address-among other pressing particle physics questions-the possibility of short and long baseline electron neutrino and antineutrino appearance. MicroBooNE, a 170 ton LArTPC under construction, is the next necessary step in a phased R&D effort toward construction and stable operation of larger-scale LArTPC's. This development effort also leans heavily on the ArgoNeuT and LAr1 LArTPC R&D experiments at Fermilab. In addition to advancing the LArTPC technology, these projects also provide unique physics opportunities. For example, Micro-BooNE will be located in the Booster Neutrino Beamline at Fermilab, at ∼470 m from neutrino production. Thus, in addition to measuring a suite of low energy neutrino cross sections on argon, MicroBooNE will investigate the anomalous low energy excess seen by the MiniBooNE experiment. Furthermore, the neutrino beam energy and relatively short baseline provide MicroBooNE with sensitivity to high-∼m2 neutrino oscillations. These proceedings summarize the role of the MicroBooNE detector in the US LArTPC R&D program, present its physics reach, and briefly discuss the physics potential of a dedicated near-future neutrino oscillation program at the Booster Neutrino Beamline, as a way to maximize the physics output of the Fermilab LArTPC R&D projects.

  3. Preparation of PFS coagulant by sectionalized reactor

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    The oxidation rate of ferrous sulfate is investigated for the preparation of polyferric sulfate(PFS) coagulant.It is proved that this reaction is zero order with respect to Fe2 +,first order with respect to NO2 (g),and first order with respect to the interface area between gas phase and liquid phase.According to this mechanism,sectionalized reactor(SR) is used in place of traditional reactor(TR),and the liquid of reaction mixture is recycled by pump.As a result,not only the flow path of reaction liquid is prolonged,but also gas-liquid contact area enlarged,and the reaction distinctly accelerated,compared with traditional reactor.The effects of parameters including temperature,acidity and others on the reaction rate are also discussed.

  4. Quinine-Induced Disseminated Intravascular Coagulation

    Directory of Open Access Journals (Sweden)

    Firas Abed

    2016-01-01

    Full Text Available Every drug comes with some side effect. It is the benefit/risk ratio that determines the medical use of the drug. Quinine, a known antimalarial drug, has been used for nocturnal leg cramps since the 1930s; it is associated with severe life-threatening hematological and cardiovascular side effects. Disseminated intravascular coagulation (DIC, albeit rare, is a known coagulopathy associated with Quinine. It is imperative to inquire about the Quinine intake in medication history in patients with coagulopathy, as most patients still consider it a harmless home remedy for nocturnal leg cramps. In this report, we present a case of coagulopathy in a middle-aged woman, who gave a history of taking Quinine for nocturnal leg cramps, as her home remedy. Early identification of the offending agent led to the diagnosis, prompt discontinuation of the medication, and complete recovery and prevented the future possibility of recurrence.

  5. Contact activation of blood-plasma coagulation

    Science.gov (United States)

    Golas, Avantika

    Surface engineering of biomaterials with improved hemocompatibility is an imperative, given the widespread global need for cardiovascular devices. Research summarized in this dissertation focuses on contact activation of FXII in buffer and blood plasma frequently referred to as autoactivation. The extant theory of contact activation imparts FXII autoactivation ability to negatively charged, hydrophilic surfaces. According to this theory, contact activation of plasma involves assembly of proteins comprising an "activation complex" on activating surfaces mediated by specific chemical interactions between complex proteins and the surface. This work has made key discoveries that significantly improve our core understanding of contact activation and unravel the existing paradigm of plasma coagulation. It is shown herein that contact activation of blood factor XII (FXII, Hageman factor) in neat-buffer solution exhibits a parabolic profile when scaled as a function of silanized-glass-particle activator surface energy (measured as advancing water adhesion tension t°a=g° Iv costheta in dyne/cm, where g°Iv is water interfacial tension in dyne/cm and theta is the advancing contact angle). Nearly equal activation is observed at the extremes of activator water-wetting properties --36 < t°a < 72 dyne/cm (O° ≤ theta < 120°), falling sharply through a broad minimum within the 20 < t°a < 40 dyne/cm (55° < theta < 75°). Furthermore, contact activation of FXII in buffer solution produces an ensemble of protein fragments exhibiting either procoagulant properties in plasma (proteolysis of blood factor XI or prekallikrein), amidolytic properties (cleavage of s-2302 chromogen), or the ability to suppress autoactivation through currently unknown biochemistry. The relative proportions of these fragments depend on activator surface chemistry/energy. We have also discovered that contact activation is moderated by adsorption of plasma proteins unrelated to coagulation through an

  6. Treatment of Textile Wastewaterby Adsorption and Coagulation

    Directory of Open Access Journals (Sweden)

    Himanshu Patel

    2010-01-01

    Full Text Available The composite of wastewater treatment was carried out using activated charcoal as adsorbent to remove COD, BOD, color in which various parameters like adsorbent dose, contact duration, temperature and agitator speed were considered. The adsorbent behavior can be explained on the basis of Freundlich and Langmuir adsorption isotherm model. Maximum removal (87.6, 81.0 and 90.0% of COD, BOD and color respectively was found at adsorbent dosage of 11 g/L. Also, the textile mill wastewater was treated with different doses of coagulants like alum, ferric sulphate and ferrous sulphate at constant contact duration (4 hours and room temperature (300 K. Percentage reduction (maximum corresponds to 80.2, 74.0 and 84.9% was obtained for removal of COD, BOD and color respectively.

  7. Using chloramine as a coagulant aid in enhancing coagulation of Yellow River water in China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Considering that contaminated raw water mostly contains high Ammonia-N and a majority of water treatment plants use prechlorination process in China, efficiency of chloramines as a coagulant aid in enhancing coagulation was investigated by Jar stirring and pilot-scale tests, using Yellow River water containing high concentration of natural organic matters (NOM) and bromide in winter. The jar tests results showed that, compared with no preoxidation, preformed chloramine apparently decreased the turbidity of settled and filtered water with low dosage (2.0 mg/L), and the aid-coagulation efficiency was further enhanced with the increase of chlorine (Cl2) to Ammonia-N (N) ratio. Pilot-scale studies indicated that, in comparison to the case without preoxidation, the turbidity removal efficiency of flotation and filtration effluent water was significantly improved, the particle counts of filtered water were decreased 63.4%, the average rate of filter head loss was reduced 18.2%, and filter run time was prolonged 15.7%. Therefore, chloramine preoxidation may substantially enhance the particle separation efficiency.

  8. Spectroscopic Investigation of the Argon Metastable State Through Optical Emission From Pulsed Argon Discharge

    Science.gov (United States)

    2010-07-01

    within the interstellar medium, but also occurs naturally on earth in our ionosphere, auroras, lightning, and fire. Artificial sources can also...collide with another particle and exchange energy. Some electrons may travel further, and therefore increase their energy, before a collision takes place...line shape was unaffected by greater filtering, which indicated the absence of power broadening due to saturation. From the filters, the beam traveled

  9. Fibrinolytic and coagulative activities of Yersinia pestis

    Directory of Open Access Journals (Sweden)

    Timo K. Korhonen

    2013-07-01

    Full Text Available The outer membrane protease Pla belongs to the omptin protease family spread by horizontal gene transfer into Gram-negative bacteria that infect animals or plants. Pla has adapted to support the life style of the plague bacterium Yersinia pestis. Pla has a -barrel fold with 10 membrane-spanning  strands and five surface loops, and the barrel surface contains bound lipopolysaccharide (LPS that is critical for the conformation and the activity of Pla. The biological activity of Pla is influenced by the structure of the surface loops around the active site groove and by temperature-induced LPS modifications. Several of the putative virulence-related functions documented for Pla in vitro address control of the human hemostatic system, i.e. coagulation and fibrinolysis. Pla activates human plasminogen to the serine protease plasmin and activates the physiological plasminogen activator urokinase. Pla also inactivates the protease inhibitors alpha-2-antiplasmin and plasminogen activator inhibitor 1 and prevents the activation of thrombin-activatable fibrinolysis inhibitor. These functions enhance uncontrolled fibrinolysis which is thought to improve Y. pestis dissemination and survival in the mammalian host, and lowered fibrin(ogen deposition has indeed been observed in mice infected with Pla-positive Y. pestis. However, Pla also inactivates an anticoagulant, the tissue factor pathway inhibitor, which should increase fibrin formation and clotting. Thus Pla and Y. pestis have complex interactions with the hemostatic system. Y. pestis modifies its LPS upon transfer to the mammalian host and we hypothesize that the contrasting biological activities of Pla in coagulation and fibrinolysis are influenced by LPS changes during infection.

  10. A short contemporary history of disseminated intravascular coagulation.

    Science.gov (United States)

    Levi, Marcel; van der Poll, Tom

    2014-11-01

    Disseminated intravascular coagulation (DIC) is a syndrome characterized by systemic intravascular activation of coagulation, leading to a widespread deposition of fibrin in the circulation. There is ample experimental and pathological evidence that the fibrin deposition contributes to multiple organ failure. The massive and ongoing activation of coagulation may result in depletion of platelets and coagulation factors, which may cause bleeding (consumption coagulopathy). The syndrome of DIC is well known in the medical literature for centuries, although a more precise description of the underlying mechanisms had to await the 20th century. Initial ideas on a role of the contact activation system as the primary trigger for the systemic activation of coagulation as well as a presumed hyperfibrinolytic response in DIC have been found to be misconceptions. Experimental and clinical evidence now indicate that the initiation of coagulation in DIC is caused by tissue factor expression, which in combination with downregulated physiological anticoagulant pathways and impaired fibrinolysis leads to widespread fibrin deposition. In addition, an extensive bidirectional interaction between coagulation and inflammation may further contribute to the pathogenesis of DIC.

  11. Thromboelastometry in patients with severe sepsis and disseminated intravascular coagulation.

    Science.gov (United States)

    Sivula, Mirka; Pettilä, Ville; Niemi, Tomi T; Varpula, Marjut; Kuitunen, Anne H

    2009-09-01

    Severe sepsis induces coagulopathy, which may lead to disseminated intravascular coagulation (DIC). Thromboelastometry is a point-of-care whole blood coagulation monitor, which has been validated in human endotoxemia model. We assessed thromboelastometry in severe sepsis and overt DIC and investigated its applicability in differentiating sepsis-related coagulation disturbances. Thromboelastometry (EXTEM and FIBTEM tests) and traditional coagulation assays were analyzed in 28 patients with severe sepsis, 12 of who fulfilled the criteria of overt DIC on admission. Ten healthy persons served as controls. Coagulation parameters, clotting time, clot formation time (CFT), alpha angle, maximal clot firmness (MCF) and lysis index at 60 min, were registered. In patients with overt DIC, EXTEM MCF, CFT and alpha angle differed from that in both healthy controls and patients without DIC, indicating hypocoagulation (MCF 52, 63 and 68 mm; CFT 184, 88 and 73 s; and alpha angle 58, 72 and 76 degrees , respectively, P coagulation assays showed progressively worsening coagulopathy from controls to septic patients without DIC and further to those with overt DIC. We conclude that thromboelastometry may be a valuable tool in assessing whole blood coagulation capacity in patients with severe sepsis with and without overt DIC.

  12. Effect of coagulation pretreatment on the fouling of ultrafiltration membrane

    Institute of Scientific and Technical Information of China (English)

    DONG Bing-zhi; CHEN Yan; GAO Nai-yun; FAN Jin-chu

    2007-01-01

    The purpose of this study is to understand the effect and mechanism of preventing membrane fouling,by coagulation pretreatment,in terms of fractional component and molecular weight of natural organic matter(NOM).A relatively higher molecular weight(MW)of hydrophobic compounds was responsible for a rapid decline in the ultrafiltration flux.Coagulation could effectively remove the hydrophobic organics.resulting in the increase of flux.It was found that a lower MW of neutral hydrophilic compounds,which could remove inadequately by coagulation.was responsible for tlle slow declining flux.The fluxes in the filtration of coagulated water and supematant water were compared and the results showed that a lower MW of neutral hydrophilic compounds remained in the supernatant water after coagulation could be rejected by a membrane,resulting in fouling.It was also found that the coagulated flocs could absorb neutral hydrophilic compounds effectively.Therefore,with the coagulated flocs formed on the membrane surface,the flux decline could be improved.

  13. Fuzzy Based Auto-coagulation Control Through Photometric Dispersion Analyzer

    Institute of Scientific and Technical Information of China (English)

    白桦; 李圭白

    2004-01-01

    The main role of water treatment plants is to supply high-quality safe drinking water. Coagulation is one of the most important stages of surface water treatment. The photometric dispersion analyzer(PDA) is a new optical method for flocculation monitoring, and is feasible to realize coagulation feedback control. The on line modification of the coagulation control system' s set point( or optimum dosing coagulant) has influenced the application of this technology in water treatment plant for a long time. A fuzzy control system incorporating the photometric dispersion analyzer was utilized in this coagulation control system. Proposed is a fuzzy logic inference control system by using Takagi and Sugeno' s fuzzy if-then rule for the self-correction of set point on line. Programmed is the dosing rate fuzzy control system in SIEMENS small-scale programmable logic controller. A 400 L/min middle-scale water treatment plant was utilized to simulate the reaction. With the changes of raw water quality, the set point was modified correctly in time, as well as coagulant dosing rate, and residual turbility before filtration was eligible and stable. Results show that this fuzzy inference and control system performs well on the coagulation control system through PDA.

  14. Opacity measurements in shock-generated argon plasmas

    Energy Technology Data Exchange (ETDEWEB)

    Erskine, D.

    1993-07-01

    Dense plasmas having uniform and constant density and temperature are generated by passage of a planar shock wave through gas. The opacity of the plasma is accurately measured versus wavelength by recording the risetime of emitted light. This technique is applicable to a wide variety of species and plasma conditions. Initial experiments in argon have produced plasmas with 2 eV temperatures, 0.004--0.04 g/cm{sup 3} densities, and coupling parameters {Gamma} {approximately}0.3--0.7. Measurements in visible light are compared with calculations using the HOPE code. An interesting peak in the capacity at 400 nm is observed for the first time and is identified with the 4s-5p transition in excited neutral argon atoms.

  15. Breakdown voltage of metal-oxide resistors in liquid argon

    Energy Technology Data Exchange (ETDEWEB)

    Bagby, L. F. [Fermilab; Gollapinni, S. [Kansas State U.; James, C. C. [Fermilab; Jones, B. J.P. [MIT; Jostlein, H. [Fermilab; Lockwitz, S. [Fermilab; Naples, D. [Pittsburgh U.; Raaf, J. L. [Fermilab; Rameika, R. [Fermilab; Schukraft, A. [Fermilab; Strauss, T. [Bern U., LHEP; Weber, M. S. [Bern U., LHEP; Wolbers, S. A. [Fermilab

    2014-11-07

    We characterized a sample of metal-oxide resistors and measured their breakdown voltage in liquid argon by applying high voltage (HV) pulses over a 3 second period. This test mimics the situation in a HV-divider chain when a breakdown occurs and the voltage across resistors rapidly rise from the static value to much higher values. All resistors had higher breakdown voltages in liquid argon than their vendor ratings in air at room temperature. Failure modes range from full destruction to coating damage. In cases where breakdown was not catastrophic, subsequent breakdown voltages were lower in subsequent measuring runs. One resistor type withstands 131 kV pulses, the limit of the test setup.

  16. Measurement of longitudinal electron diffusion in liquid argon

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yichen, E-mail: yichen@bnl.gov [Physics Department, Brookhaven National Laboratory, 20 Pennsylvania St., Building 510E, Upton, NY 11973 (United States); Tsang, Thomas [Instrumentation Division, Brookhaven National Laboratory, 20 N. Technology St., Building 535B, Upton, NY 11973 (United States); Thorn, Craig; Qian, Xin; Diwan, Milind; Joshi, Jyoti; Kettell, Steve; Morse, William [Physics Department, Brookhaven National Laboratory, 20 Pennsylvania St., Building 510E, Upton, NY 11973 (United States); Rao, Triveni [Instrumentation Division, Brookhaven National Laboratory, 20 N. Technology St., Building 535B, Upton, NY 11973 (United States); Stewart, James; Tang, Wei; Viren, Brett [Physics Department, Brookhaven National Laboratory, 20 Pennsylvania St., Building 510E, Upton, NY 11973 (United States)

    2016-04-21

    We report the measurement of longitudinal electron diffusion coefficients in liquid argon for electric fields between 100 and 2000 V/cm with a gold photocathode as a bright electron source. The measurement principle, apparatus, and data analysis are described. In the region between 100 and 350 V/cm, our results show a discrepancy with the previous measurement [1]. In the region between 350 and 2000 V/cm, our results represent the world's best measurement. Over the entire measured electric field range, our results are systematically higher than the calculation of Atrazhev‐Timoshkin [2]. The quantum efficiency of the gold photocathode, the drift velocity and longitudinal diffusion coefficients in gas argon are also presented.

  17. Treatment of facial vascular lesions with an argon laser

    Science.gov (United States)

    Szymanczyk, Jacek; Golebiowska, Aleksandra; Michalska, I.

    1996-03-01

    Two-hundred-ninety-six patients with various vascular lesions of the face have been treated with argon laser LAK-1 in the Department of Dermatology Warsaw Medical Academy since April 1992. The diagnosis of the treated lesions was port-wine stains, multiple telangiectasiae and small, most often induced by trauma hemangioma cavernosum of the lip. Best results were achieved in the patients with small hemangiomas cavernosum of the lip and multiple telangiectasiae on the face. Cure rate in this group was 100%. In 112 port-wine stain cases fading of 50 - 75% comparing with the adjacent skin was achieved. With stress, the argon laser therapy is a method of choice for the treatment of hemangioma cavernosum, port-wine stains and multiple teleagiectasiae of the face.

  18. Detection of Cherenkov light emission in liquid argon

    Energy Technology Data Exchange (ETDEWEB)

    Antonello, M.; Arneodo, F.; Badertscher, A.; Baiboussinov, B.; Baldo Ceolin, M.; Battistoni, G.; Bekman, B.; Benetti, P.; Bernardini, E.; Bischofberger, M.; Borio di Tigliole, A.; Brunetti, R.; Bueno, A.; Calligarich, E.; Campanelli, M.; Carpanese, C.; Cavalli, D.; Cavanna, F. E-mail: flavio.cavanna@aquila.infn.it; Cennini, P.; Centro, S.; Cesana, A.; Chen, C.; Chen, D.; Chen, D.B.; Chen, Y.; Cieslik, C.; Cline, D.; Dai, Z.; De Vecchi, C.; Dabrowska, A.; Dolfini, R.; Felcini, M.; Ferrari, A.; Ferri, F.; Ge, Y.; Gibin, D.; Gigli Berzolari, A.; Gil-Botella, I.; Graczyk, K.; Grandi, L.; Guglielmi, A.; He, K.; Holeczek, J.; Huang, X.; Juszczak, C.; Kielczewska, D.; Kisiel, J.; Kozlowski, T.; Laffranchi, M.; Lagoda, J.; Li, Z.; Lu, F.; Ma, J.; Markiewicz, M.; Matthey, C.; Mauri, F.; Mazza, D.; Meng, G.; Messina, M.; Montanari, C.; Muraro, S.; Navas-Concha, S.; Nurzia, G.; Otwinowski, S.; Ouyang, Q.; Palamara, O.; Pascoli, D.; Periale, L.; Piano Mortari, G.B.; Piazzoli, A.; Picchi, P.; Pietropaolo, F.; Polchlopek, W.; Rancati, T.; Rappoldi, A.; Raselli, G.L.; Rico, J.; Rondio, E.; Rossella, M.; Rubbia, A.; Rubbia, C.; Sala, P.; Scannicchio, D.; Segreto, E.; Seo, Y.; Sergiampietri, F.; Sobczyk, J.; Stepaniak, J.; Szarska, M.; Szeptycka, M.; Terrani, M.; Ventura, S.; Vignoli, C.; Wang, H.; Woo, J.; Xu, G.; Xu, Z.; Zalewska, A.; Zalipska, J.; Zhang, C.; Zhang, Q.; Zhen, S.; Zipper, W

    2004-01-11

    Detection of Cherenkov light emission in liquid argon has been obtained with an ICARUS prototype, during a dedicated test run at the Gran Sasso Laboratory external facility. Ionizing tracks from cosmic ray muons crossing the detector active volume have been collected in coincidence with visible light signals from a photo-multiplier (PMT) immersed in liquid argon. A 3D reconstruction of the tracks has been performed exploiting the ICARUS imaging capability. The angular distributions of the tracks triggered by the PMT signals show an evident directionality. By means of a detailed Monte Carlo simulation we show that the geometrical characteristics of the events are compatible with the hypothesis of Cherenkov light emission as the main source of the PMT signals.

  19. Development of cryogenic installations for large liquid argon neutrino detectors

    CERN Document Server

    Adamowski, M; Geynisman, M; Hentschel, S; Montanari, D; Nessi, M; Norris, B

    2015-01-01

    A proposal for a very large liquid argon (68,000 kg) based neutrino detector is being studied. To validate the design principles and the detector technology, and to gain experience in the development of the cryostats and the cryogenic systems needed for such large experiments, several smaller scale installations will be developed and implemented, at Fermilab and CERN. The cryogenic systems for these installations will be developed, constructed, installed and commissioned by an international engineering team. These installations shall bring the required cooling power under specific conditions to the experiments for the initial cool-down and the long term operation, and shall also guarantee the correct distribution of the cooling power within the cryostats to ensure a homogeneous temperature distribution within the cryostat itself. The cryogenic systems shall also include gaseous and liquid phase argon purification devices to be used to reach and maintain the very stringent purity requirements needed for these...

  20. Infrared spectrum of the chloromethylene hydroperoxide cation in solid argon

    Science.gov (United States)

    Chen, Mohua; Zhou, Mingfei

    2013-07-01

    Infrared spectrum of the chloromethylene hydroperoxide cation, HC(Cl)OOH+ in solid argon is reported. The cation is produced by co-condensation of dichloromethane and dioxygen mixtures with high-frequency discharged argon at 4 K followed by visible light excitation. On the basis of isotopic substitutions as well as quantum chemical frequency calculations, absorptions at 3452.7, 3052.0, 1499.6, 976.9, 855.4 and 956.1 cm-1 are assigned to the O-H, C-H, Cdbnd O, C-Cl and O-O stretching and out-of-plane CH wagging vibrations of the chloromethylene hydroperoxy cation. The cation was predicted to have a singlet ground state with planar Cs symmetry.

  1. Trimming of a Migrated Biliary Nitinol Stent Using Argon Plasma

    Directory of Open Access Journals (Sweden)

    Hiroyuki Matsubayashi

    2009-07-01

    Full Text Available Metallic stent migration is a well-known complication which cannot always be managed by removal or repositioning, especially in case of uncovered stent. We report a patient who developed obstructive jaundice due to migration of an expandable metallic stent (EMS inserted in the lower bile duct. Trimming of the EMS using argon plasma was performed, with the power setting of 60 W and 2.0 l/min of argon flow. The distal part of the EMS was removed and mechanical cleaning using balloon catheter was performed for remnant EMS. Without additional stent insertion, jaundice was relieved in a few days. No complication was recognized during the procedure and no recurrence of jaundice in the rest of his life.

  2. Laser-tissue interaction of a continuous-wave 2-μm, 3-μm cascade oscillation fiber laser: sharp incision with controlled coagulation layer thickness

    Science.gov (United States)

    Arai, Tsunenori; Sumiyoshi, Tetsumi; Naruse, Kyota; Ishihara, Miya; Sato, Shunichi; Kikuchi, Makoto; Kasamatsu, Tadashi; Sekita, Hitoshi; Obara, Minoru

    2000-06-01

    We studied coagulation layer controlled incision with newly developed continuous wave 2 micrometer, 3 micrometer cascade oscillation fiber laser in vitro. Since this laser device simultaneously oscillates 2 micrometer and 3 micrometer radiation, we could change tissue interaction by arranging power ratio of 2 micrometer to 3 micrometer radiation. About one watt of total irradiation power with various power ratios was focused to extracted fresh porcine myocardium or anesthetized rabbit on an automatic moving stage to obtain line incision. Macro photograph and microscopic histology were used to observe tissue interaction phenomenon. The incised specimen showed that precise cutting groove with thin coagulation layer was attained by a 3 micrometer based radiation, meanwhile addition of 2 micrometer radiation to 3 micrometer radiation made coagulation layer thicker. A heat conduction simulator using finite-element method was used to qualitatively explain obtained coagulation layer thickness. This precise incision with controllable side coagulation layer may effective to control bleeding during incision, for instance, for skin, liver, and kidney incisions. Pure continuous wave radiation of 2 micrometer and 3 micrometer may eliminate stress wave induced tissue damage which is frequently found in Ho:YAG and/or Er:YAG tissue interactions. Moreover, sapphire fiber might offer flexible power delivery to this new laser to establish endoscopic application and/or to improved beam handling.

  3. Imperative function of electron beams in low-energy plasma focus device

    Indian Academy of Sciences (India)

    M Z Khan; L K Lim; S L Yap; C S Wong

    2015-12-01

    A 2.2 kJ plasma focus device was analysed as an electron beam and an X-ray source that operates with argon gas refilled at a specific pressure. Time-resolved X-ray signals were observed using an array of PIN diode detectors, and the electron beam energy was detected using a scintillator-assisted photomultiplier tube. The resultant X-rays were investigated by plasma focus discharge for pressures ranging from 1.5 mbar to 2.0 mbar. This range corresponded to the significant values of X-ray yields and electron beam energies from the argon plasma. The electron temperature of argon plasma at an optimum pressure range was achieved by an indirect method using five-channel BPX65 PIN diodes of aluminum foils with different thicknesses. X-ray yield, electron beam energy, and electron temperature of argon plasma were achieved at 1.5–2.0 mbar because of the strong bombardment of the energetic electron beam.

  4. Measurement of scintillation efficiency for nuclear recoils in liquid argon

    CERN Document Server

    Gastler, D; Hime, A; Stonehill, L C; Seibert, S; Klein, J; Lippincott, W H; McKinsey, D N; Nikkel, J A

    2010-01-01

    The scintillation light yield of liquid argon from nuclear recoils relative to electronic recoils has been measured as a function of recoil energy from 10 keVr up to 250 keVr. The scintillation efficiency, defined as the ratio of the nuclear recoil scintillation response to the electronic recoil response, is 0.25 \\pm 0.02 + 0.01(correlated) above 20 keVr.

  5. Monte Carlo Simulation of Argon in Nano-Space

    Institute of Scientific and Technical Information of China (English)

    CHEN Min; YANG Chun; GUO Zeng-Yuan

    2000-01-01

    Monte Carlo simulations are performed to investigate the thermodynamic properties of argon confined in nano-scale cubes constructed of graphite walls. A remarkable depression of the system pressures is observed. The simulations reveal that the length-scale of the cube, the magnitude of the interaction between the fluid and the graphite wall and the density of the fluid exhibit reasonable effects on the thermodynamic property shifts of the luid.

  6. Investigation of Non-Equilibrium Argon and Hydrogen Plasmas.

    Science.gov (United States)

    Braun, Christopher Gifford

    1987-09-01

    Theoretical and experimental investigations are made into non-equilibrium argon and hydrogen partially -ionized plasmas characteristic of glow discharge devices such as thyratrons and discharge tubes. For an argon plasma, the development and use of a collisional-radiative, steady -state, three-energy-level model is presented and experimental measurements on pulsed argon plasmas are briefly mentioned. Two different theoretical argon plasma models are discussed; the first is numerically solved using a non-Maxwellian electron distribution function, while the second is solved analytically, including atom-atom inelastic collisions, assuming Maxwellian electron and atom distribution functions. For a hydrogen plasma, experimental measurements using fluorescence and laser-induced fluorescence have been made in a modified hydrogen thyratron over a wide current density range (from 100 to 8,000 A/cm('2)) for the atomic hydrogen population densities n = 2,3,4. A pronounced rise in the atomic hydrogen excited state populations is observed after the end of the current pulse. A new method to measure the time-resolved electron density has been developed and results are presented. A time-dependent model for atomic hydrogen plasmas typical of a thyratron has been constructed, and preliminary results are shown. This model includes ten atomic energy levels (n = 1 to n = 9 and the continuum), takes into account energy balance with an externally supplied current density and assumes a Maxwellian electron distribution function. Implications of these measurements and theoretical analysis upon the operation of thyratrons are discussed. (Copies available exclusively from Micrographics Department, Doheny Library, University of Southern California, Los Angeles, CA 90089 -0182.).

  7. Liquid Argon Hadronic EndCap Production Database

    CERN Document Server

    Oram, C J; Wielers, M

    2004-01-01

    This document describes the contents of the Liquid Argon Hadronic EndCap (HEC) Production Database. At the time of the PRR (Production Readiness Review), the groups responsible for the production of the LAr HEC components and modules were required to provide a detailed plan as to what data should be stored in the production database and how the data should be accessed, displayed and queried in all reasonable foreseeable circumstances. This document describes the final database.

  8. Argon laser photocoagulation of cyclodialysis clefts after cataract surgery

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, B. [Univ. of Lund, Dept. of Ophthalmology, Lund (Sweden)

    1995-06-01

    Three patients with cyclodialysis clefts, hypotony and hypotonic retinopathy subsequent to cataract surgery were treated with argon laser photocoagulation. The hypotony was reversed in each patient and their visual acuity was normalized. Laser photocoagulation is a noninvasive treatment that can be repeated easily and safely. The complications of the treatment are minor. A hypertensive episode commonly occurs in the early postoperative period. (au) 8 refs.

  9. Current concepts in the management of disseminated intravascular coagulation.

    Science.gov (United States)

    Thachil, Jecko; Toh, Cheng Hock

    2012-04-01

    Disseminated Intravascular Coagulation is a clinicopathological syndrome where widespread intravascular coagulation occurs in response to an inciting process. The pathophysiology for this disorder is complex with an important role for thrombin, the central regulator of the coagulation process. Since the clinical spectrum of DIC is variable due to its dynamic nature, the laboratory diagnosis should ideally be not based on a single marker or an isolated set of results. The treatment should primary focus on the management of the underlying triggering condition with blood products used as resuscitative measures. Newer therapeutic modalities have been recently tried with success although the management of DIC still remains a major challenge.

  10. Pro-coagulant activity of human mesenchymal stem cells.

    Science.gov (United States)

    Christy, Barbara A; Herzig, Maryanne C; Montgomery, Robbie K; Delavan, Christopher; Bynum, James A; Reddoch, Kristin M; Cap, Andrew P

    2017-04-05

    Allogeneic mesenchymal stem cells (MSCs) show great potential for the treatment of military and civilian trauma, based on their reduced immunogenicity and ability to modulate inflammation and immune function in the recipient. Although generally considered to be safe, MSCs express tissue factor (TF), a potent activator of coagulation. In the current study, we evaluated multiple MSC populations for tissue factor expression and pro-coagulant activity in order to characterize safety considerations for systemic use of MSCs in trauma patients who may have altered coagulation homeostasis. Multiple MSC populations derived from either human adipose tissue or bone marrow were expanded in the recommended stem cell media. Stem cell identity was confirmed using a well-characterized panel of positive and negative markers. Tissue factor expression on the cell surface was evaluated by flow cytometry with anti-CD142 antibody. Effects on blood coagulation were determined by thromboelastography (TEG) and calibrated automated thrombogram (CAT) assays using platelet poor plasma or whole blood. MSCs express tissue factor on their surfaces and are pro-coagulant in the presence of blood or plasma. The adipose-derived MSCs (Ad-MSC) evaluated were more pro-coagulant and expressed more tissue factor than bone marrow MSCs (BM-MSCs), which showed a greater variability in TF expression. BM-MSCs were identified that exhibited low pro-coagulant activity, whereas all Ad-MSCs examined exhibited high pro-coagulant activity. The percentage of cells in a given population expressing surface tissue factor correlates roughly with functional pro-coagulant activity. MSC tissue factor expression and pro-coagulant activity change over time in culture. All MSC populations are not equivalent; care should be taken to select cells for clinical use that minimize potential safety problems and maximize chance of patient benefit. Adipose-derived MSCs appear more consistently pro-coagulant than BM-MSCs, presenting a

  11. A loop of coagulation factor VIIa influencing macromolecular substrate specificity

    DEFF Research Database (Denmark)

    Bjelke, Jais R; Persson, Egon; Rasmussen, Hanne B;

    2006-01-01

    Coagulation factor VIIa (FVIIa) belongs to a family of proteases being part of the stepwise, self-amplifying blood coagulation cascade. To investigate the impact of the mutation Met(298{156})Lys in FVIIa, we replaced the Gly(283{140})-Met(298{156}) loop with the corresponding loop of factor Xa....../Met(298{156})Lys-FVIIa with almost the same activity and specificity profile. We conclude that a lysine residue in position 298{156} of FVIIa requires a hydrophilic environment to be fully accommodated. This position appears critical for substrate specificity among the proteases of the blood coagulation...

  12. Changes in the human blood coagulating system during prolonged hypokinesia

    Science.gov (United States)

    Filatova, L. M.; Anashkin, O. D.

    1978-01-01

    Changes in the coagulating system of the blood were studied in six subjects during prolonged hypokinesia. Thrombogenic properties of the blood rose in all cases on the 8th day. These changes are explained by stress reaction due to unusual conditions for a healthy person. Changes in the blood coagulating system in the group subjected to physical exercise and without it ran a practically parallel course. Apparently physical exercise is insufficient to prevent such changes that appear in the coagulating system of the blood during prolonged hypokinesia.

  13. Implementation of a microcontroller-based semi-automatic coagulator.

    Science.gov (United States)

    Chan, K; Kirumira, A; Elkateeb, A

    2001-01-01

    The coagulator is an instrument used in hospitals to detect clot formation as a function of time. Generally, these coagulators are very expensive and therefore not affordable by a doctors' office and small clinics. The objective of this project is to design and implement a low cost semi-automatic coagulator (SAC) prototype. The SAC is capable of assaying up to 12 samples and can perform the following tests: prothrombin time (PT), activated partial thromboplastin time (APTT), and PT/APTT combination. The prototype has been tested successfully.

  14. Metal clusters on supported argon layers; Metallcluster auf dielektrischen Substraten

    Energy Technology Data Exchange (ETDEWEB)

    Faber, Bernhard

    2011-10-21

    The deposition of small sodium clusters on supported Ar(001)-surfaces is simulated. Theoretical description is achieved by a hierarchical model consisting of time-dependent DFT and molecular dynamics. The valence electrons of the sodium atoms are considered by Kohn-Sham-Scheme with self interaction correction. The interaction of argon atoms and sodium ions is described by atom-atom potentials whereas the coupling to the QM electrons is done by local pseudo-potentials. A decisive part of the model is the dynamical polarizability of the rare-gas atoms. The optional metal support is considered by the method of image charges. The influence of the forces caused by image charges and the influence of the number of argon monolayers on structure, optical response and deposition dynamics of Na{sub 6} and Na{sub 8} is investigated. There is very little influence on cluster structure and only a small shift of the cluster perpendicular to the surface. Concerning optical response the position of the Mie plasmon peak stays robust whereas the details of spectral fragmentation react very sensitively to changes. The forces caused by image charges of the metal support play only a little role with the dynamics of deposition while the thickness of the argon surface strongly influences the dissipation. (orig.)

  15. Bacteria Inactivation Using DBD Plasma Jet in Atmospheric Pressure Argon

    Institute of Scientific and Technical Information of China (English)

    XU Guimin; ZHANG Guanjun; SHI Xingmin; MA Yue; WANG Ning; LI Yuan

    2009-01-01

    A coaxial dielectric barrier discharge plasma jet Was designed,which can be operated in atmospheric pressure argon under an intermediate frequency sinusoidal resonant power supply,and an atmospheric pressure glow-like discharge Was achieved.Two kinds of typical bacteria,i.e.,the Staphylococcus aureus(S.aurens)and Escherichia coil(E.coil),were employed to study the bacterial inactivation mechanism by means of the non-thermal plasma.The killing log value (KLV)of S.aureus reached up to 5.38 with a treatment time of 90 s and that of E.coil up to 5.36 with 60 s,respectively.According to the argon emission spectra of the plasma jet and the scanning electron microscope (SEM) images of the two bacteria before and after the plasma treatment.it is concluded that the reactive species in the argon plasma played a major role in the bacterial inactivation,while the heat,electric field and UV photons had little effect.

  16. Isotopic fractionation of argon during stepwise release from shungite

    Science.gov (United States)

    Rison, W.

    1980-05-01

    It is noted that in previous attempts to determine the Ar-40/Ar-36 ratio in the ancient atmosphere, the only direct measurement yielding a value below the atmospheric value of today is for argon released at low temperatures from a pre-Cambrian shungite. In the present work, a low value for Ar-40/Ar-36 in gas released from a type I shungite at low temperatures is confirmed. Attention is given to a study of the accompanying Ar-38/Ar-36 ratios and the enhanced ratio of Ar-40/Ar-36 for the fractions released at high temperatures which shows that the effect observed is a result of the stepwise heating and the argon diffusion mobilized thereby. It is suggested that the low Ar-40/Ar-36 obtained in the past is from the same source rather than reflecting the isotropic composition of the pre-Cambrian atmosphere, and that the type I shungite may exhibit simple volume diffusion over macroscopic dimensions as glasses do. It is concluded that if this is so, the diffusion parameters obtained from the data would imply rapid exchange with the atmosphere for any argon initially trapped in the veins of the material.

  17. Space-charge effects in liquid argon ionization chambers

    Science.gov (United States)

    Rutherfoord, J. P.; Walker, R. B.

    2015-03-01

    We have uniformly irradiated liquid argon ionization chambers with betas from high-activity 90Sr sources. The radiation environment is similar to that in the liquid argon calorimeters which are part of the ATLAS detector installed at CERN's Large Hadron Collider (LHC). We measured the resulting ionization current over a wide range of applied potential for two different source activities and for three different chamber gaps. These studies provide operating experience at exceptionally high ionization rates. In particular they indicate a stability at the 0.1% level for these calorimeters over years of operation at the full LHC luminosity when operated in the normal mode at an electric field E = 1.0 kV / mm. We can operate these chambers in the normal mode or in the space-charge limited regime and thereby determine the transition point between the two. This transition point is parameterized by a positive argon ion mobility of μ+ = 0.08 ± 0.02mm2 / V s at a temperature of 88.0±0.5 K and at a pressure of 1.02±0.02 bar. In the space-charge limited regime the ionization currents are degraded and show signs of instability. At the highest electric fields in our study (6.7 kV/mm) the ionization current is still slowly rising with increasing electric field.

  18. Cryogenic Tests of the Atlas Liquid Argon Calorimeter

    CERN Document Server

    Fabre, C; Chalifour, M; Gonidec, A; Passardi, Giorgio

    2006-01-01

    The ATLAS liquid argon calorimeter consists of the barrel and two end-cap detectors housed in three independent cryostats filled with a total volume of 78 m3 of liquid argon. During cool-down the temperature differences in the composite structure of the detectors must be kept within strict limits to avoid excessive mechanical stresses and relative displacements. During normal operation the formation of gas bubbles, which are detrimental to the functioning of the detector, must be prevented and temperature gradients of less than 0.7 K across the argon bath are mandatory due to the temperature dependence of the energy measurements. Between April 2004 and May 2005 the barrel (120 t) and one end-cap (219 t) underwent qualification tests at the operating temperature of 87.3 K using a dedicated test facility at ground level. These tests provided a validation of the cooling methods to be adopted in the final underground configuration. In total 6.9 GJ and 15.7 GJ were extracted from the calorimeters and a temperature...

  19. Free electron lifetime achievements in liquid Argon imaging TPC

    Energy Technology Data Exchange (ETDEWEB)

    Baibussinov, B; Ceolin, M Baldo; Centro, S; Cieslik, K; Farnese, C; Fava, A; Gibin, D; Guglielmi, A; Meng, G; Pietropaolo, F; Varanini, F; Ventura, S [INFN, Sezione di Padova via Marzolo 8, I-35131 Padova (Italy); Calligarich, E [INFN, Sezione di Pavia via Bassi 6, I-27100 Pavia (Italy); Rubbia, C, E-mail: Carlo.Rubbia@cern.c [Laboratori Nazionali del Gran Sasso dell' INFN I-67010 Assergi (Italy)

    2010-03-15

    A key feature for the success of the liquid Argon imaging TPC (LAr-TPC) technology is the industrial purification against electro-negative impurities, especially Oxygen and Nitrogen remnants, which have to be continuously kept at an exceptionally low level by filtering and recirculating liquid Argon. Improved purification techniques have been applied to a 120 liters LAr-TPC test facility in the INFN-LNL laboratory. Through-going muon tracks have been used to determine the free electron lifetime in liquid Argon against electro-negative impurities. The short path length here observed (30 cm) is compensated by the high accuracy in the observation of the specific ionization of cosmic ray muons at sea level as a function of the drift distance. A free electron lifetime of tau {approx} (21.4{sup +7.3}{sub -4.3}) ms, namely > 15.8 ms at 90% C.L. has been observed over several weeks under stable conditions, corresponding to a residual Oxygen equivalent of {approx} 15 ppt (part per trillion). At 500 V/cm, the free electron speed is 1.5 mm/mus. In a LAr-TPC a free electron lifetime in excess of 15 ms corresponds for instance to an attenuation of less than 20% after a drift path of 5 m, opening the way to the operation of the LAr-TPC with exceptionally long drift distances.

  20. Vacuum ultraviolet radiation emitted by microwave driven argon plasmas

    Science.gov (United States)

    Espinho, S.; Felizardo, E.; Henriques, J.; Tatarova, E.

    2017-04-01

    Vacuum ultraviolet (VUV) radiation emitted by microwave driven argon plasmas has been investigated at low-pressure conditions (0.36 mbar). A classical surface-wave sustained discharge at 2.45 GHz has been used as plasma source. VUV radiation has been detected by emission spectroscopy in the 30-125 nm spectral range. The spectrum exhibits atomic and ionic argon emissions with the most intense spectral lines corresponding to the atomic resonance lines, at 104.8 nm and 106.7 nm, and to the ion lines, at 92.0 nm and 93.2 nm. Emissions at lower wavelengths were also detected, including lines with no information concerning level transitions in the well-known NIST database (e.g., the atomic line at 89.4 nm). The dependence of the lines' intensity on the microwave power delivered to the launcher was investigated. The electron density was estimated to be around 1012 cm-3 using the Stark broadening of the hydrogen Hβ line at 486.1 nm. The main population and loss mechanisms considered in the model for the excited argon atom and ion states emitting in the VUV range are discussed. The experimental results were compared to self-consistent model predictions, and a good agreement was obtained.

  1. Calculation of the rate of coagulation of hydrophobic colloids in the non-steady state

    NARCIS (Netherlands)

    Roebersen, G.J.; Wiersema, P.H.

    1974-01-01

    In accurate coagulation measurements, the observed coagulation rate should be extrapolated to time zero to find the rate of formation of doublets from singlet particles. In the theoretical calculation of coagulation rates, generally a steady state is assumed. At the onset of coagulation, however, a

  2. Effect of nano-scale curvature on the intrinsic blood coagulation system

    OpenAIRE

    Kushida, Takashi; Saha, Krishnendu; Subramani, Chandramouleeswaran; Nandwana, Vikas; Rotello, Vincent M.

    2014-01-01

    The intrinsic coagulation activity of silica nanoparticles strongly depends on their surface curvature. Nanoparticles with higher surface curvature do not denature blood coagulation factor XII on its surface, providing a coagulation ‘silent’ surface, while nanoparticles with lower surface curvature shows denaturation and concomitant coagulation.

  3. Calculation of the rate of coagulation of hydrophobic colloids in the non-steady state

    NARCIS (Netherlands)

    Roebersen, G.J.; Wiersema, P.H.

    1974-01-01

    In accurate coagulation measurements, the observed coagulation rate should be extrapolated to time zero to find the rate of formation of doublets from singlet particles. In the theoretical calculation of coagulation rates, generally a steady state is assumed. At the onset of coagulation, however, a

  4. K-Ar age of young volcanic rocks and excess argon--Binary mixing model and quantitative study of excess argon effect

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    A binary mixing model for excess argon is suggested in the note. According to this model and the data of excess argon component obtained in our experiment , a quantitative study of the effect of excess argon on real K-Ar age of young volcanic rocks is done. The result indicates that the effect of 5% excess argon component in samples on K-Ar age of the samples more than 2 Ma is less than 7.36% and can lead K-Ar age of 0.5 Ma samples to increase by 32.4%, while 1% excess argon component leads K-Ar age of 0.5 Ma samples to increase by 6.26%. Therefore, when pre-processed excess argon component is ≤1%, K-Ar age of the samples more than 0.5 Ma should be credible. On this basis we suggest a principal opinion for evaluation of previous K-Ar dating results and propose that the matrix is used to determine K-Ar age of young volcanic rocks. For the samples less than 0.2 Ma, in the case of high excess argon content, even if only 1% excess argon component exists in their matrix, it can also greatly affect their K-A age. Thus it must be careful to treat the dating result.

  5. Removal of titanium dioxide nanoparticles by coagulation: effects of coagulants, typical ions, alkalinity and natural organic matters.

    Science.gov (United States)

    Wang, H T; Ye, Y Y; Qi, J; Li, F T; Tang, Y L

    2013-01-01

    To investigate the possibility of removing titanium dioxide nanoparticles (TiO2 NPs) from water by coagulation, as well as to find the optimal coagulant and experimental conditions for TiO2 NP removal, four types of coagulant were adopted: polyferric sulfate (PFS), ferric chloride (FeCl3), polyaluminum chloride (PACl), and alum (Al2(SO4)3). It was found that the removal of TiO2 NPs by coagulation was affected by ionic strength, alkalinity, as well as types and dosages of coagulants. PFS and FeCl3 achieved much higher removal efficiency of TiO2 NPs than PACl and Al2(SO4)3 did. For 30 mg/L TiO2 NPs, a dosage of 0.3 mM PFS (as Fe) achieved 84% removal after coagulation followed by 30 min settlement. Optimal ionic strength (0.1 M NaCl or 0.03 M CaCl2) is of vital importance for the performance of PFS. Na2SO4 is unfavorable for the performance of PFS. Optimal alkalinity (0.01-0.03 M NaHCO3) is necessary for FeCl3 to remove TiO2 NPs. Natural organic matter, as represented by humic acid (HA) up to 11 mg/L, reduces the removal of TiO2 NPs by coagulation. These findings indicate that coagulation is a good option for the removal of TiO2 NPs from water, and more attention should be paid to the effects of water quality when using coagulation to remove TiO2 NPs from aqueous matrices. This provides a possible solution to alleviate the potential hazard caused by TiO2 NPs.

  6. Influence of natural coagulants on isoflavones and antioxidant activity of tofu.

    Science.gov (United States)

    Rekha, C R; Vijayalakshmi, G

    2010-08-01

    Tofu (instead of preparing using synthetic coagulant) was prepared using coagulants of plant origin (Citrus limonum, Garcinia indica, Tamarindus indica, Phyllanthus acidus and Passiflora edulis). Total crude protein and fat contents were highest in tofu prepared using G. indica and T. indica (72.5% dbw) compared to synthetic coagulant. Tofu prepared with natural coagulants had signifi cantly higher antioxidant activity compared to synthetic coagulant. Bioconversion of isoflavone glucosides (daidzin and genistin) into their corresponding bioactive aglycones (daidzein and genistein) was observed in tofu. The difference between glucosides and aglycones contents in soy milk was significant but there was not much difference in tofu coagulated with synthetic and natural coagulants.

  7. Impacts of epichlorohydrin-dimethylamine on coagulation performance and membrane fouling in coagulation/ultrafiltration combined process with different Al-based coagulants.

    Science.gov (United States)

    Bu, Fan; Gao, Baoyu; Li, Ruihua; Sun, Shenglei; Yue, Qinyan

    2016-09-01

    Two kinds of aluminum-based coagulants and epichlorohydrin-dimethylamine (DAM-ECH) were used in the treatment of humic acid-kaolin simulated water by coagulation-ultrafiltration (C-UF) hybrid process. Coagulation performance, floc characteristics, including floc size, compact degree, and strength were investigated in this study. Ultrafiltration experiments were conducted by a dead-end batch unit to implement the resistance analyses to explore the membrane fouling mechanisms. Results showed that DAM-ECH aid significantly increased the UV254 and DOC removal efficiencies and contributed to the formation of larger and stronger flocs with a looser structure. Aluminum chloride (Al) gave rise to better coagulation performance with DAM-ECH compared with poly aluminum chloride (PACl). The consequences of ultrafiltration experiments showed that DAM-ECH aid could reduce the membrane fouling mainly by decreasing the cake layer resistance. The flux reductions for PACl, Al/DAM-ECH (dosing both Al and DAM-ECH) and PACl/DAM-ECH (dosing both PACl and DAM-ECH) were 62%, 56% and 44%, respectively. Results of this study would be beneficial for the application of PACl/DAM-ECH and Al/DAM-ECH composite coagulants in water treatment processes. Copyright © 2016 Elsevier Ltd. All rights reserved.

  8. Resonance broadening of argon lines in a micro-scaled atmospheric pressure plasma jet (argon μAPPJ)

    Science.gov (United States)

    Pipa, A. V.; Ionikh, Yu. Z.; Chekishev, V. M.; Dünnbier, M.; Reuter, S.

    2015-06-01

    Optical emission from atmospheric pressure micro-jet operating with pure argon (argon μAPPJ) flow has been detected with a moderate resolution spectrometer. Large broadening of the several argon (Ar) lines has been observed in the near infrared spectral region. This effect was attributed to resonance broadening of the s2 (Paschen notation) level in 3p54s configuration. In the present work, corresponding line profiles are suggested for plasma diagnostics. For this, a general case of resonance broadening coefficient of noble gases is discussed. As broadening reflects the Ar density, and the static gas pressure of the jet is in equilibrium with the ambient, the local gas temperature can be inferred. An estimation of gas temperature from the width of the 750 nm Ar line is in agreement with rotational temperature of OH radicals determined from the A2Σ+ → X2Π (0, 0) band. At low temperatures (300-600 K) and at partial Ar pressure near atmospheric, the resonance width of the suggested lines is very sensitive to small temperature variations. High temperature sensitivity and large width make the resonance broadened lines very attractive for diagnostics of low temperature discharges at elevated pressure, e.g., as they are used in plasma-medicine.

  9. Disseminated intravascular coagulation: a review for the internist.

    Science.gov (United States)

    Levi, Marcel; van der Poll, Tom

    2013-02-01

    Disseminated intravascular coagulation (DIC) is a syndrome characterized by systemic intravascular activation of coagulation, leading to widespread deposition of fibrin in the circulation. Recent knowledge on important pathogenetic mechanisms that may lead to DIC has resulted in novel preventive and therapeutic approaches to patients with DIC. The diagnosis of DIC can be made by sensitive laboratory tests; however, most of these tests are not readily available in a clinical setting. A reliable diagnosis can also be made on the basis of a small series of laboratory tests that can be combined in a scoring algorithm. The cornerstone of the management of DIC is the specific and vigorous treatment of the underlying disorder. Strategies aimed at the inhibition of coagulation activation may theoretically be justified and have been found beneficial in experimental and clinical studies. These strategies comprise inhibition of tissue factor-mediated activation of coagulation or restoration of physiological anticoagulant pathways.

  10. Performance of Solanum incunum Linnaeus as natural coagulant ...

    African Journals Online (AJOL)

    hope&shola

    ISSN 1996-0786 ©2011 Academic Journals. Full Length ... that S. incunum is promising as coagulant and disinfectant product for water purification. ... it acceptable for release or reuse. ... to interfere with maintenance of a free chlorine residual.

  11. Treatability of South African surface waters by enhanced coagulation

    African Journals Online (AJOL)

    2013-06-05

    Jun 5, 2013 ... The majority of South African inland surface water sources are compromised due to a ... minimising residual coagulant, minimising sludge production .... included as being indicative of the worst effects of indirect reuse.

  12. Surgical Coagulator With Carbon Dioxide Laser For Gynecology

    Science.gov (United States)

    Wolinski, Wieslaw; Kazmirowski, Antoni; Korobowicz, Witold; Olborski, Zbigniew

    1987-10-01

    The technical data and parameters of the CO2 surgical laser for gynecology are given. Coagulator was designed and constructed in Institute of Microelectronics and Optoelectronics Warsaw Technical University.

  13. Coagulation profile in patients undergoing video-assisted thoracoscopic lobectomy

    DEFF Research Database (Denmark)

    Christensen, Thomas Decker; Vad, Henrik; Pedersen, Søren

    2017-01-01

    -, and the first two days postoperatively by standard coagulation blood test, thromboelastometry (ROTEM®) and thrombin generation. RESULTS: Patients undergoing potential curative surgery for lung cancer were not hypercoagulable preoperatively. There was no statistically significant difference in the majority...

  14. CARDIOVASCULAR AND BLOOD COAGULATION EFFECTS OF PULMONARY ZINC EXPOSURE

    Science.gov (United States)

    Cardiovascular damage induced by pulmonary exposure to environmental chemicals can result from direct action or, secondarily, from pulmonary injury. We have developed a rat model of pulmonary exposure to zinc to demonstrate cardiac, coagulative, and fibrinolytic alterations. Mal...

  15. Bio-responsive polymer hydrogels homeostatically regulate blood coagulation

    Science.gov (United States)

    Maitz, Manfred F.; Freudenberg, Uwe; Tsurkan, Mikhail V.; Fischer, Marion; Beyrich, Theresa; Werner, Carsten

    2013-01-01

    Bio-responsive polymer architectures can empower medical therapies by engaging molecular feedback-response mechanisms resembling the homeostatic adaptation of living tissues to varying environmental constraints. Here we show that a blood coagulation-responsive hydrogel system can deliver heparin in amounts triggered by the environmental levels of thrombin, the key enzyme of the coagulation cascade, which—in turn—becomes inactivated due to released heparin. The bio-responsive hydrogel quantitatively quenches blood coagulation over several hours in the presence of pro-coagulant stimuli and during repeated incubation with fresh, non-anticoagulated blood. These features enable the introduced material to provide sustainable, autoregulated anticoagulation, addressing a key challenge of many medical therapies. Beyond that, the explored concept may facilitate the development of materials that allow the effective and controlled application of drugs and biomolecules. PMID:23868446

  16. Thrombomodulin: A Bifunctional Modulator of Inflammation and Coagulation in Sepsis

    Directory of Open Access Journals (Sweden)

    Takayuki Okamoto

    2012-01-01

    Full Text Available Deregulated interplay between inflammation and coagulation plays a pivotal role in the pathogenesis of sepsis. Therapeutic approaches that simultaneously target both inflammation and coagulation hold great promise for the treatment of sepsis. Thrombomodulin is an endogenous anticoagulant protein that, in cooperation with protein C and thrombin-activatable fibrinolysis inhibitor, serves to maintain the endothelial microenvironment in an anti-inflammatory and anticoagulant state. A recombinant soluble form of thrombomodulin has been approved to treat patients suffering from disseminated intravascular coagulation (DIC and has thus far shown greater therapeutic potential than heparin. A phase II clinical trial is currently underway in the USA to study the efficacy of thrombomodulin for the treatment of sepsis with DIC complications. This paper focuses on the critical roles that thrombomodulin plays at the intersection of inflammation and coagulation and proposes the possible existence of interactions with integrins via protein C. Finally, we provide a rationale for the clinical application of thrombomodulin for alleviating sepsis.

  17. PARTICLE ELECTROSTATIC COAGULATION AND ITS APPLICATIONS IN DUST CONTROL

    Institute of Scientific and Technical Information of China (English)

    顾强; 刘炳江

    1995-01-01

    Fine particulates instead of others create particulate pollution and they are easier to escape from almost all conventional collectors of low-or medium-efficiency. It is of practical significance to take full advantages of particle coagulation by electrostatic forces to upgrade the collentors' performance. This paper investigates the main mechanisms of coagulation, an possiboie trostatic forces existing in the collectors and their effects on the particle coagulation. To make particle kinetic coagulation electrostaticaUy enhanced be a step of the conventional collectors' operations,certain conditions should be created through some modifications of the collectors. Based on that, the authors suggest that a precharger electro-cyclone technique be applied to improve the performance of common cyclones still widely used in many places. And a preliminary semi-industrial test has been carried out at Jiawang Power Station, Xuzhou, Jiangsu Province, and the results show that the modified cyclone increases its efficiency from about 800% to. 92-94%.

  18. Carbon dioxide pressure-induced coagulation of microalgae.

    Science.gov (United States)

    Lee, Roland; Jessop, Philip G; Champagne, Pascale

    2015-12-28

    The move to a low-carbon economy has generated renewed interest in microalgae for the production of biofuels with the potential mutual benefit of wastewater treatment. However, harvesting has been identified as a limiting factor to the economic viability of this process. This paper explores the harvesting of microalgae using high-pressure gas without the addition of coagulants. Coagulation of microalgae under high-pressure gas was found to be an efficient method to separate algae from suspension. The critical coagulation pressures (CCPs) for H(2) and CO(2) were determined to be 6.1 and 6.2 MPa, respectively. The CO(2)-induced decrease in solution pH positively influenced coagulation rates, without appearing to affect the CCP. This approach could be beneficial for the economic removal of microalgae from solution for the production of both biofuels and biomedical compounds without the addition of non-environmentally friendly chemicals. © 2015 The Author(s).

  19. optimization of coagulation-flocculation process for colour removal ...

    African Journals Online (AJOL)

    user

    ... as an alternative for conventional coagulants that are widely used in dye wastewater treatment plants. ... biological treatment techniques used are aerobic degradation ... for colour removal from industrial wastewater due to its efficiency and ...

  20. Optical and thermal simulations of noninvasive laser coagulation of the human vas deferens

    Science.gov (United States)

    Schweinsberger, Gino R.; Cilip, Christopher M.; Trammell, Susan R.; Cherukuri, Harish; Fried, Nathaniel M.

    2011-03-01

    Successful noninvasive laser coagulation of the canine vas deferens, in vivo, has been previously reported. However, there is a significant difference between the optical properties of canine and human skin. In this study, Monte Carlo simulations of light transport through tissue and heat transfer simulations are performed to determine the feasibility of noninvasive laser vasectomy in humans. A laser wavelength of 1064 nm was chosen for deep optical penetration in tissue. Monte Carlo simulations determined the spatial distribution of absorbed photons inside the tissue layers (epidermis, dermis, and vas). The results were convolved with a 3-mm-diameter laser beam, and then used as the spatial heat source for the heat transfer model. A laser pulse duration of 500 ms and pulse rate of 1 Hz, and cryogen spray cooling were incident on the tissue for 60 s. Average laser power (5-9 W), cryogen pulse duration (60-100 ms), cryogen cooling rate (0.5-1.0 Hz), and increase in optical transmission due to optical clearing (0-50 %), were studied. After application of an optical clearing agent to increase skin transmission by 50%, an average laser power of 6 W, cryogen pulse duration of 60 ms, and cryogen cooling rate of 1 Hz resulted in vas temperatures of ~ 60°C, sufficient for thermal coagulation, while 1 mm of the skin surface (epidermis and dermis) remained at a safe temperature of ~ 45 °C. Monte Carlo and heat transfer simulations indicate that it is possible to noninvasively thermally coagulate the human vas without adverse effects (e.g. scrotal skin burns), if an optical clearing agent is applied to the skin prior to the procedure.

  1. Application of Dual Coagulant (Alum + Barley in Removing Colour from Leachate

    Directory of Open Access Journals (Sweden)

    Shaylinda Mohd Zin Nur

    2017-01-01

    Full Text Available Coagulation/flocculation is one of the treatment method for highly polluted leachate. One of the main affecting factor for this process is the coagulant used. Coagulant is divided into natural and chemical coagulant. In the current study, Alum (chemical coagulant and barley (natural coagulant were used as dual coagulant. The aim of this study is to examine the effectiveness of dual coagulant made from alum and barley in removing colour from the effluent of Simpang Renggam landfill leachate aeration lagoon through coagulation/flocculation method. Coagulation/flocculation process with single alum coagulant, single barley coagulant and dual coagulant (alum+barley were examined by evaluating the optimum values of pH and dose. Optimum dose and pH for alum and barley as single coagulant were; 3 g/L & pH 5; 0.8 g/L & pH 6. Higher removal of colour was recorded for alum compared to barley. Application of alum and barley as dual coagulant had higher colour removal than alum and barley as single coagulant. The optimum pH and dose for dual coagulant were at pH 6, 3.0 g/L of alum and 0.8 g/L of barley respectively. However, at pH 6, 2 g/L alum and 1.6 g/L barley, the removal of colour was similar to alum at 3 g/L. It can be concluded that barley as coagulant aid able to reduce 33 % usage of alum at par removals of colour. Thus, the dual coagulant consist of alum and barley has the potential to be applied as a coagulant for leachate treatment.

  2. Removal of Arsenic from Drinking Water by Adsorption and Coagulation

    Science.gov (United States)

    Zhang, M.; Sugita, H.; Hara, J.; Takahashi, S.

    2013-12-01

    Removal of arsenic from drinking water has been an important issue worldwide, which has attracted greater attentions in recent years especially for supplying safe drinking water in developing countries. Although many kinds of treatment approaches that are available or applicable both in principle and practice, such as adsorption, coagulation, membrane filtration, ion exchange, biological process, electrocoagulation and so on, the first 2 approaches (i.e., adsorption and coagulation) are most promising due to the low-cost, high-efficiency, simplicity of treating systems, and thus can be practically used in developing countries. In this study, a literature survey on water quality in Bangladesh was performed to understand the ranges of arsenic concentration and pH of groundwater in Bangladesh. A series of tests were then organized and performed to investigate the effects of arsenic concentration, arsenic forms, pH, chemical compositions of the materials used for adsorption and coagulation, particle size distribution and treatment time on quality of treated water. The experimental results obtained in the study illustrated that both adsorption and coagulation can be used to effectively reduce the concentrations of either arsenic (V) or arsenic (III) from the contaminated water. Coagulation of arsenic with a magnesium-based material developed in this study can be very effective to remove arsenic, especially arsenic (V), from contaminated water with a concentration of 10 ppm to an undetectable level of 0.002 ppm by ICP analyses. Compared to arsenic (III), arsenic (V) is easier to be removed. The materials used for adsorption and coagulation in this study can remove arsenic (V) up to 9 mg/g and 6 mg/g, and arsenic (III) up to 4 mg/g and 3 mg/g, respectively, depending on test conditions and compositions of the materials being used. The control of pH during treatment can be a challenging technical issue for developing both adsorbent and coagulant. Keywords: Water Treatment

  3. Verification of high efficient broad beam cold cathode ion source

    Science.gov (United States)

    Abdel Reheem, A. M.; Ahmed, M. M.; Abdelhamid, M. M.; Ashour, A. H.

    2016-08-01

    An improved form of cold cathode ion source has been designed and constructed. It consists of stainless steel hollow cylinder anode and stainless steel cathode disc, which are separated by a Teflon flange. The electrical discharge and output characteristics have been measured at different pressures using argon, nitrogen, and oxygen gases. The ion exit aperture shape and optimum distance between ion collector plate and cathode disc are studied. The stable discharge current and maximum output ion beam current have been obtained using grid exit aperture. It was found that the optimum distance between ion collector plate and ion exit aperture is equal to 6.25 cm. The cold cathode ion source is used to deposit aluminum coating layer on AZ31 magnesium alloy using argon ion beam current which equals 600 μA. Scanning electron microscope and X-ray diffraction techniques used for characterizing samples before and after aluminum deposition.

  4. Coagulation-flocculation in leachate treatment using modified micro sand

    Science.gov (United States)

    Thaldiri, Nur Hanani; Halim, Azhar Abdul

    2013-11-01

    Sanitary landfill leachate is considered as highly polluted wastewater, without any treatment, discharging into water system will cause underground water and surface water pollutions. This study was to investigate the treatability of the semi-aerobic landfill leachate via coagulation-flocculation using poly-aluminum chloride (PAC), cationic polymer, and modified micro sand. Leachate was collected from Pulau Burung Sanitary Landfill (PBSL) located in Penang, Malaysia. Coagulation-flocculation was performed by using jar test equipment and the effect of pH, dose of coagulant and dose of polymer toward removal of chemical oxygen demand (COD), color and suspended solid (SS) were examined. Micro sand was also used in this study to compare settling time of coagulation-flocculation process. The optimum pH, dose of coagulant (PAC) and dose of polymer (cationic) achieved were 7.0, 1000 mg/L and 8 mg/L, respectively. The dose of micro sand used for the settling time process was 300 mg/L. Results showed that 52.66% removal of COD, 97.16% removal of SS and 96.44% removal of color were achieved under optimum condition. The settling times for the settling down of the sludge or particles that formed during coagulation-flocculation process were 1 min with modified sand, 20 min with raw micro sand and 45 min without micro sand.

  5. Modeling of particle coagulation in low pressure PECVD

    Science.gov (United States)

    Bhandarkar, U.; Kortshagen, U.

    1998-10-01

    Contaminant particles generated in plasmas used to manufacture semiconductor devices can potentially destroy micro-electronic circuits. Particles of micrometer-size in a plasma are usually negatively charged due to the higher mobility of electrons. Like charges on the particles should inhibit growth by coagulation. However, the coagulation rates of nanometer-sized particles observed experimentally are even higher than the thermal coagulation rates of uncharged particles. This observation implies the presence of positively charged nano-particles along with the negative ones such that the mutual attraction enhances coagulation. We propose photo-detachment of electrons due to UV radiation as a potential path for the generation of positively charged particles. We have developed a self-consistent plasma-coagulation model based on the General Dynamic Equation which is well-known from aerosol research. Plasma properties are determined self-consistently using a global plasma model. The particle charge distribution is calculated using a charging module which also accounts for UV photo-detachment. Preliminary results of this model yield coagulation rates consistent with those observed experimentally.

  6. Activation of blood coagulation in cancer: implications for tumour progression.

    Science.gov (United States)

    Lima, Luize G; Monteiro, Robson Q

    2013-09-04

    Several studies have suggested a role for blood coagulation proteins in tumour progression. Herein, we discuss (1) the activation of the blood clotting cascade in the tumour microenvironment and its impact on primary tumour growth; (2) the intravascular activation of blood coagulation and its impact on tumour metastasis and cancer-associated thrombosis; and (3) antitumour therapies that target blood-coagulation-associated proteins. Expression levels of the clotting initiator protein TF (tissue factor) have been correlated with tumour cell aggressiveness. Simultaneous TF expression and PS (phosphatidylserine) exposure by tumour cells promote the extravascular activation of blood coagulation. The generation of blood coagulation enzymes in the tumour microenvironment may trigger the activation of PARs (protease-activated receptors). In particular, PAR1 and PAR2 have been associated with many aspects of tumour biology. The procoagulant activity of circulating tumour cells favours metastasis, whereas the release of TF-bearing MVs (microvesicles) into the circulation has been correlated with cancer-associated thrombosis. Given the role of coagulation proteins in tumour progression, it has been proposed that they could be targets for the development of new antitumour therapies.

  7. Removal of dispersant-stabilized carbon nanotubes by regular coagulants

    Institute of Scientific and Technical Information of China (English)

    Ni Liu; Changli Liu; Jing Zhang; Daohui Lin

    2012-01-01

    Coagulation followed by sedimentation,as a conventional technique in the water treatment plant,can be the first line of defense against exposures of carbon nanotubes(CNTs)to aquatic organisms and human beings,which has been rarely documented.This study investigated the removal of dispersant-stabilized CNT suspensions by poly aluminum chloride(PAC1)and KAI(SO4)2·12H2O (alum),with a focus on the effects of dispersant type,coagulant type and dosage.PAC1 performed better than alum in the removal of tannic acid-,humic acid-,and sodium dodecyl benzenesulfonate-stabilized CNTs,but worse for polyethylene glycol octylphenyl ether(TX100)-stabilized CNTs.Neither coagulant could effectively precipitate cetyltrimethyl ammonium bromide-stabilized CNTs.The removal by PAC1 first increased up to a plateau and then decreased with the continued increase of coagulant dosage.However,the removal rates leveled off but did not decrease after achieving their highest level with the continued addition of alum.The coagulation and flocculation of the CNT suspensions by PAC1 could be regulated mainly by the mechanism of adsorption charge neutralization,whereas the coagulation by alum mainly involved electrical double-layer compression.

  8. Coagulation properties of anelectrochemically prepared polyaluminum chloride containing active chlorine

    Institute of Scientific and Technical Information of China (English)

    HU Chengzhi; LIU Huijuan; QU Jiuhui

    2006-01-01

    With high content of the Al13 species and the active chloride, an electrochemically prepared polyaluminum chloride (E-PACl) presents integrated efficiency of coagulation and oxidation. The coagulation properties of E-PACl were systemically investigated through jar tests in the various water quality conditions. The active chlorine in E-PACl can significantly influence the coagulation behavior due to the active chlorine preoxidation, which can change the surface charge characteristic of organic matter (OM) in water. The active chlorine preoxidation could improve the E-PACl coagulation efficiency if the water possessed the characteristics of relatively low OM content (2 mg/L) and high hardness (278 mg CaCO3/L). In the water with medium content of OM (5 mg/L), dosage would be a crucial factor to decide whether the active chlorine in E-PACl aided coagulation process or not. Comparing with alkaline condition, active chlorine would show a more significant influence on the coagulation process in acidic region.

  9. The effects of coagulants on the structure of PBO materials

    Institute of Scientific and Technical Information of China (English)

    LI Jin-huan; HUANG Yu-dong; MENG Lin

    2006-01-01

    PBO materials possess super mechanical properties and high thermal and chemical resistance due to their special rigid-rod backbones with heterocyclic chemical structure and supermolecular microstructure. But these structures may be affected by a series of preparing technologies, among which the coagulant is even more important. In this paper the chemical and microstructure changes of PBO materials coagulated with different solvents were investigated. Analyses of molecular weight and chemical structure of PBO coagulated indicate that the heterocyclic ring of PBO will experience cleavage in coagulation and in this stage water plays an important role. The final structure of PBO materials may involve several intermediate structures lying between benzoxazole and the open ring. Wide-angle X-ray diffraction (WAXD) 2θ scans and scanning probe microscope (SPM) show that the microstructure of PBO materials coagulated in solvents with different properties will change a lot and those coagulants with the smaller rate of diffusion like methanol can cause more ordered molecule alignment containing fewer voids.

  10. Does whole blood coagulation analysis reflect developmental haemostasis?

    Science.gov (United States)

    Ravn, Hanne Berg; Andreasen, Jo Bnding; Hvas, Anne-Mette

    2016-07-27

    Developmental haemostasis has been well documented over the last 3 decades and age-dependent reference ranges have been reported for a number of plasmatic coagulation parameters. With the increasing use of whole blood point-of-care tests like rotational thromboelastometry (ROTEM) and platelet function tests, an evaluation of age-dependent changes is warranted for these tests as well. We obtained blood samples from 149 children, aged 1 day to 5.9 years, and analysed conventional plasmatic coagulation tests, including activated partial prothrombin time, prothrombin time, and fibrinogen (functional). Whole blood samples were analysed using ROTEM to assess overall coagulation capacity and Multiplate analyzer to evaluate platelet aggregation. Age-dependent changes were analysed for all variables. We found age-dependent differences in all conventional coagulation tests (all P values coagulation assessment when applying ROTEM, apart from clotting time in the EXTEM assay (P coagulation test. However, these age-dependent changes were not displayed in whole blood monitoring using ROTEM or Multiplate analyzer. Type of anticoagulant had a significant influence on platelet aggregation across all age groups.

  11. Beam loading

    CERN Document Server

    Gamp, Alexander

    2013-01-01

    We begin by giving a description of the radio-frequency generator-cavity-beam coupled system in terms of basic quantities. Taking beam loading and cavity detuning into account, expressions for the cavity impedance as seen by the generator and as seen by the beam are derived. Subsequently methods of beam-loading compensation by cavity detuning, radio-frequency feedback and feedforward are described. Examples of digital radio-frequency phase and amplitude control for the special case of superconducting cavities are also given. Finally, a dedicated phase loop for damping synchrotron oscillations is discussed.

  12. Coagulation of humic waters for diffused pollution control and the influence of coagulant type on DOC fractions removed.

    Science.gov (United States)

    Heiderscheidt, Elisangela; Leiviskä, Tiina; Kløve, Bjørn

    2016-10-01

    This study examined the suitability of organic coagulants for treatment of typically humic peat extraction runoff water by comparing their performance with that of ferric sulphate (FS). The influence of coagulant type on dissolved organic carbon (DOC) fractions removed was analysed in detail using LC-OCD-OND (size exclusion liquid chromatography coupled with organic carbon and organic nitrogen detection) fractionation techniques. In general, lower coagulant dosage was needed under acidic (pH 4.5) than neutral (pH 6.5) conditions. Chitosan (Chit) and poly (diallyldimethyl) ammonium chloride (pDMAC) required significantly lower dosage (40-55%) than FS for acceptable purification, while a tannin-based coagulant (Tan2) required substantially higher dosage (55-75%) independent of water pH. FS demonstrated the best removal of DOC (polymers demonstrated satisfactory overall performance, achieving purification rates mostly inside the requirements set by Finnish environmental authorities.

  13. [Shock and coagulation disorders in systemic mastocytosis].

    Science.gov (United States)

    Hansen, U; Wiese, R; Knolle, J

    1994-09-16

    A 41-year-old man was admitted in circulatory shock of unknown aetiology (systolic pressure 50 mm Hg) and marked reddening of the upper part of the body as well as maculopapular rash over the whole body. After 1500 ml of colloidal solution had been infused the blood pressure rose to a level at which the patient's condition was no longer at risk. He reported having had a similar attack of flushing and circulatory collapse during the last few years, each time after drinking 3-41 of beer. Laboratory tests showed thromboplastin time 56%, partial thromboplastin time 130 s and thrombin time > 180 s. Three hours after admission the coagulation times had further deteriorated, but had become normal within 20 hours. After rest and after a provocation (hot bath) the serum concentrations were: heparin 0.21 U/ml and 0.85 U/ml; histamine 1.9 micrograms/ml and 2.3 micrograms/ml; serotonin 23 micrograms/ml and 38 micrograms/ml. Histological examination of an iliac crest bone marrow biopsy revealed dense collections of mast cells, as seen in systemic mastocytosis. A skin biopsy was diagnostic of urticaria pigmentosa.

  14. Blood coagulation reactions on nanoscale membrane surfaces

    Science.gov (United States)

    Pureza, Vincent S.

    Blood coagulation requires the assembly of several membrane-bound protein complexes composed of regulatory and catalytic subunits. The biomembranes involved in these reactions not only provide a platform for these procoagulant proteins, but can also affect their function. Increased exposure of acidic phospholipids on the outer leaflet of the plasma membrane can dramatically modulate the catalytic efficiencies of such membrane-bound enzymes. Under physiologic conditions, however, these phospholipids spontaneously cluster into a patchwork of membrane microdomains upon which membrane binding proteins may preferentially assemble. As a result, the membrane composition surrounding these proteins is largely unknown. Through the development and use of a nanometer-scale bilayer system that provides rigorous control of the phospholipid membrane environment, I investigated the role of phosphatidylserine, an acidic phospholipid, in the direct vicinity (within nanometers) of two critical membrane-bound procoagulant protein complexes and their respective natural substrates. Here, I present how the assembly and function of the tissue factor˙factor VIIa and factor Va˙factor Xa complexes, the first and final cofactor˙enzyme complexes of the blood clotting cascade, respectively, are mediated by changes in their immediate phospholipid environments.

  15. Inflammation and coagulation in urticaria and angioedema.

    Science.gov (United States)

    Cugno, Massimo; Asero, Riccardo; Tedeschi, Alberto; Lazzari, Riccardo; Marzano, Angelo V

    2012-09-01

    Urticaria is a skin disease characterised by short-lived surface swellings of the dermis (wheals) frequently accompanied by itching. It is classified as acute or chronic depending on whether the wheal recurrence occurs for less or more than six weeks. Acute urticaria is often due to a hypersensitivity reaction, whereas about 50% of the cases of chronic urticaria are regarded as autoimmune. Urticaria may occur alone or in association with a deeper swelling (angioedema) involving the subcutaneous and/or submucosal tissues, and last from hours to a few days. Angioedema can also develop alone, and may be idiopathic or be caused by allergies, inherited or acquired deficiencies of C1-inhibitor protein, or adverse drug reactions. An interplay between inflammation and coagulation has been proposed as a pathomechanism in urticaria and urticaria-associated angioedema (in which histamine and thrombin are involved), as well as in angioedema due to C1-inhibitor deficiency, which involves various biological systems. An increase in the plasma markers of thrombin generation, fibrinolysis and inflammation has been documented during exacerbations of urticaria and angioedema, with the marker levels decreasing to normal during remission. However, the hypercoagulable state in chronic urticaria and angioedema has not been reported to be associated with any increased risk of thrombosis, although there have been a number of reports of cardiovascular events occurring during episodes of acute urticaria. These observations have provided the rationale for the clinical evaluation of anticoagulant and antifibrinolytic drugs, the efficacy of which has sometimes been demonstrated.

  16. Accelerators for the PS neutrino beam

    CERN Document Server

    Steerenberg, R; Gschwendtner, E; Pardons, A; Vincke, H

    2013-01-01

    A recent memorandum for an experimental proposal [1] was discussed during the CERN PS and SPS experimental committee (SPSC) of April 2011 and at the Research Board of June 2011. The proposed experiment, with objective to investigate the anomalous ν(μ) → ν(e) oscillations, aims at re-using the discontinued CERN PS Neutrino Facility (PSNF) and experimental zones to install a 150 ton liquid argon time projection chamber (LArTPC) as near detector and a 600 ton LArTPC as far detector. This article will summarize the experimental needs, the proposed facility layout, a primary beam production scheme and the requirements for the reconstruction of the PSNF.

  17. Measuring Muon-Neutrino Charged-Current Differential Cross Sections with a Liquid Argon Time Projection Chamber

    Energy Technology Data Exchange (ETDEWEB)

    Spitz, Joshua B. [Yale Univ., New Haven, CT (United States)

    2011-01-01

    More than 80 years after its proposed existence, the neutrino remains largely mysterious and elusive. Precision measurements of the neutrino's properties are just now beginning to take place. Such measurements are required in order to determine the mass of the neutrino, how many neutrinos there are, if neutrinos are different than anti-neutrinos, and more. Muon-neutrino charged-current differential cross sections on an argon target in terms of the outgoing muon momentum and angle are presented. The measurements have been taken with the ArgoNeuT Liquid Argon Time Projection Chamber (LArTPC) experiment. ArgoNeuT is the first LArTPC to ever take data in a low energy neutrino beam, having collected thousands of neutrino and anti-neutrino events in the NuMI beamline at Fermilab. The results are relevant for long baseline neutrino oscillation experiments searching for non-zero $\\theta_{13}$, CP-violation in the lepton sector, and the sign of the neutrino mass hierarchy, among other things. Furthermore, the differential cross sections are important for understanding the nature of the neutrino-nucleus interaction in general. These measurements represent a significant step forward for LArTPC technology as they are among the first neutrino physics results with such a device.

  18. Performance of the ATLAS Liquid Argon Calorimeter after three years of LHC operation and plans for a future upgrade

    CERN Document Server

    Nikiforou, N; The ATLAS collaboration

    2013-01-01

    The ATLAS experiment is designed to study the proton-proton collisions produced at the Large Hadron Collider(LHC) at CERN. Liquid argon sampling calorimeters are used for all electromagnetic calorimetry covering the pseudo-rapidity region up to 3.2, as well as for hadronic calorimetry in the range 1.4-4.9. The electromagnetic calorimeters use lead as passive material and are characterized by an accordion geometry that allows a fast and uniform azimuthal response without any gap. Copper and tungsten were chosen as passive material for the hadronic calorimetry; whereas a classic plate geometry was adopted at large polar angles, an innovative one based on cylindrical electrodes with thin argon gaps was designed for the coverage at low angles, where the particles flow is higher. All detectors are housed in three cryostats kept at 87 K. After installation in 2004-2006, the calorimeters were extensively commissioned over the three years period prior to first collisions in 2009, using cosmic rays and single LHC beam...

  19. Performance of the ATLAS Liquid Argon Calorimeter after three years of LHC operation and plans for a future upgrade.

    CERN Document Server

    Strizenec, P; The ATLAS collaboration

    2014-01-01

    The ATLAS experiment is designed to study the proton-proton collisions produced at the Large Hadron Collider (LHC) at CERN. Liquid argon sampling calorimeters are used for all electromagnetic calorimetry covering the pseudorapidity region up to 3.2, as well as for hadronic calorimetry in the range 1.4-4.9. The electromagnetic calorimeters use lead as passive material and are characterized by an accordion geometry that allows a fast and uniform azimuthal response. Copper and tungsten were chosen as passive material for the hadronic calorimetry; whereas a parallel plate geometry was adopted at large polar angles, an innovative one based on cylindrical electrodes with thin argon gaps was designed for the coverage at low angles, where the particles flow is higher. All detectors are housed in three cryostats kept at 88.5 K. After installation in 2004-2006, the calorimeters were extensively commissioned over the three years period prior to first collisions in 2009, using cosmic rays and single LHC beams. Since then...

  20. Amplification of femtosecond vacuum ultraviolet laser pulses at 126 nm in an optical-field-induced ionized argon plasma

    Science.gov (United States)

    Kubodera, Shoichi; Kaku, Masanori; Katto, Masahito; Miyazaki, Kenzo

    2012-10-01

    Short-wavelength lasers in the vacuum ultraviolet (VUV) spectral region between 100 and 200 nm have not yet been developed to the same degree as visible and infrared lasers. We have been developing the argon excimer laser at 126 nm by using an optical-field-induced ionized (OFI) argon plasma. We have observed the gain of 0.86 /cm at 126 nm in the OFI Ar plasma, which was produced inside a hollow fiber with a diameter of 250 microns and a length of 5 cm. In this paper, we have used the OFI plasma gain medium as an amplifier of the 126 nm radiation. A femtosecond 126 nm pulse was produced by the seventh-order nonlinear wavelength conversion of a femtosecond Ti:sapphire laser at 882 nm. The femtosecond wavelength-converted coherent VUV beam was then injected inside the OFI plasma that was produced by the same Ti:sapphire laser, resulting in a 2.4-fold increase of the VUV intensity with one-pass amplification. The gain-length product of 0.87 with the one-pass amplification was evaluated, which was consistent with the value we have observed in the previous measurements. The further extension of the OFI plasma by using a hollow fiber would be plausible to increase the gain-length product and the VUV amplified intensity.

  1. Effects of argon gas flow rate and guide shell on oxygen concentration in Czochralski silicon growth

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    φ200 mm silicon single crystals were grown in the φ450 mm hot zone of a Czochralski (CZ) furnace. By modifying the pattern and the velocity of the argon flow, the silicon single crystals with different oxygen concentrations were obtained. Through numerical simulation, the velocity of the argon gas flow was plotted for the first time. The experiment results were analyzed and the optimum condition of the argon flow with the lowest oxygen concentration was obtained.

  2. Enhanced WWTP effluent organic matter removal in hybrid ozonation-coagulation (HOC) process catalyzed by Al-based coagulant

    Energy Technology Data Exchange (ETDEWEB)

    Jin, Xin [School of Environmental and Municipal Engineering, Xi’an University of Architecture and Technology, Xi’an, Shaanxi Province, 710055 (China); Jin, Pengkang, E-mail: pkjin@hotmail.com [School of Environmental and Municipal Engineering, Xi’an University of Architecture and Technology, Xi’an, Shaanxi Province, 710055 (China); Hou, Rui [School of Environmental and Municipal Engineering, Xi’an University of Architecture and Technology, Xi’an, Shaanxi Province, 710055 (China); Yang, Lei [Department of Materials Science and Engineering, Monash University, Clayton, VIC, 3800 (Australia); Wang, Xiaochang C., E-mail: xcwang@xauat.edu.cn [School of Environmental and Municipal Engineering, Xi’an University of Architecture and Technology, Xi’an, Shaanxi Province, 710055 (China)

    2017-04-05

    Highlights: • A novel HOC process was firstly put forward to apply in wastewater reclamation. • Interactions between ozone and Al-based coagulants was found in the HOC process. • Ozonation can be catalyzed and enhanced by Al-based coagulants in the HOC process. • HOC process showed better organics removal than pre-ozonation-coagulation process. - Abstract: A novel hybrid ozonation-coagulation (HOC) process was developed for application in wastewater reclamation. In this process, ozonation and coagulation occurred simultaneously within a single unit. Compared with the conventional pre-ozonation-coagulation process, the HOC process exhibited much better performance in removing dissolved organic matters. In particular, the maximal organic matters removal efficiency was obtained at the ozone dosage of 1 mgO{sub 3}/mg DOC at each pH value (pH 5, 7 and 9). In order to interpret the mechanism of the HOC process, ozone decomposition was monitored. The results indicated that ozone decomposed much faster in the HOC process. Moreover, by using the reagent of O{sub 3}-resistant hydroxyl radical (·OH) probe compound, para-chlorobenzoic acid (pCBA), and electron paramagnetic resonance (EPR) analysis, it was observed that the HOC process generated higher content of ·OH compared with pre-ozonation process. This indicates that the ·OH oxidation reaction as the key step can be catalyzed and enhanced by Al-based coagulants and their hydrolyzed products in this developed process. Thus, based on the catalytic effects of Al-based coagulants on ozonation, the HOC process provides a promising alternative to the conventional technology for wastewater reclamation in terms of higher efficiency.

  3. Extreme Ultraviolet Beam-Foil Spectroscopy of Highly Ionized Neon and Argon.

    Science.gov (United States)

    1986-08-01

    velocity v, where the cross sections for electron capture scale as v- . For example, 99 Andresen and Veje calculate a maximum capture cross section into s...Andresen, S. Hultberg, B. Jelenkovic, L. Liljeby, S. Mannervik and E. Veje , Z. Physik A 242, 101 (1979). 88. B. Andresen, B. Denne, J. 0. Ekberg, L...A. Trigueiros and E. Veje , Phys. Rev. A 26, 2468 (1982). 90. H. D. Betz, D. Roschenthaler and J. Rothermel, Phys. Rev. Ltr. 50, 34 (1983). 91. A

  4. Measurement of the drift field in the ARGONTUBE LAr TPC with 266~nm pulsed laser beams

    CERN Document Server

    Ereditato, A; Janos, S; Kreslo, I; Luethi, M; von Rohr, C Rudolf; Schenk, M; Strauss, T; Weber, M S; Zeller, M

    2014-01-01

    ARGONTUBE is a liquid argon time projection chamber (LAr TPC) with a drift field generated in-situ by a Greinacher voltage multiplier circuit. We present results on the measurement of the drift field distribution based on a simplified model of a multi-stage Greinacher circuit, by using straight ionization tracks generated by an intense UV laser beam.

  5. Optimisation of combined coagulation and microfiltration for water treatment.

    Science.gov (United States)

    Judd, S J; Hillis, P

    2001-08-01

    The effect of upstream coagulant dosing for full-flow microfiltration of an upland-reservoir water has been investigated. The process, run under conditions of constant flux and pH and based on a ferric salt, is compared with a published study of another full-flow process based on alum dosing and operated at constant pressure and coagulant concentration. The current study includes data for the residual deposit remaining following backflushing by reverse flow. Results are presented in terms of the specific-cake resistance (R'o, m(-2)) as a function of pH or coagulant dose. Reasonable correlation with classical cake filtration theory was obtained, such that R' was assumed to be independent of run time and cake thickness. The following trends have been noted: The optimum pH for the alum-based system appears to be between 7.5 and 8 on the basis of cake resistance. The effect of coagulant dose between 18 and 71 microM Fe3+ is much more significant than a change in pH between 5 and 9 for the alum system: a 53-fold increase in specific flux compared with a 7-fold increase with reference to the limiting R'o values at pH 4.8 and 7.7. A low coagulant dose (0.018mM, 1.0 mg l(-1) Fe3+) appears to have a slightly detrimental effect on downstream microfiltration operation. The low coagulant doses apparently cause incomplete aggregation of colloidal particles such that internal fouling of the membrane takes place. The residual (cleaning cycle) deposit resistance followed roughly the same trend as the backflush cycle-cake resistance with coagulant concentration, but with a much reduced value (about 16 times lower, on average). An optimum coagulant dose of 0.055 mM (3.1 mg/l) Fe3+ can be identified on the basis of operational cost based on coagulant cost and cake resistance, all other aspects of the system being substantially unchanged. It is concluded that coagulation with downstream microfiltration offers a cost-effective means of removing natural organic matter, achieving a THMFP

  6. Effects of argon flow on impurities transport in a directional solidification furnace for silicon solar cells

    Science.gov (United States)

    Li, Zaoyang; Liu, Lijun; Ma, Wencheng; Kakimoto, Koichi

    2011-03-01

    A global simulation including coupled oxygen and carbon transport was carried out to study the argon flow effects on the impurities transport in a directional solidification furnace for silicon solar cells. The simulation is based on a fully coupled calculation of the thermal and flow fields in a furnace including argon gas flow and melt convection. Five chemical reactions are considered in the impurity transport model. The effects of both the argon flow rate and the furnace pressure were examined. It was found that the argon flow has an important effect on the silicon melt convection, which will further influence the evaporation characteristic of SiO at the melt free surface. The amount of SiO carried away by the argon flow increases with increase in the argon flow rate while the CO gas can be prevented from being transported to the melt free surface. There exists a peak value for the concentration of impurities in the furnace chamber regarding argon flow rate due to the correlation among SiO evaporated, reacted and taken away. The pressure also influences the impurity transport in the furnace by modifying the pattern of argon flow. The numerical results demonstrate a method to control the oxygen and carbon transport in a directional solidification furnace by adjusting the argon flow rate and the furnace pressure.

  7. Influence of argon laser curing on resin bond strength.

    Science.gov (United States)

    Hinoura, K; Miyazaki, M; Onose, H

    1993-04-01

    Light cured resin composites are usually cured with halogen lamps whose light output decreases with time and distance to the resin surface. This study compared bond strengths of resins to tooth structure cured with either an argon laser or a conventional halogen light. The enamel and dentin of bovine incisors were ground on the buccal surface with wet #600 grit SiC paper. A 4 x 2 mm mold was placed on the tooth surface and Scotchbond 2/Silux and Clearfil Photobond/Photo Clearfil A were placed into the molds and cured using a Quick Light or an argon laser for exposure times of 10, 20, and 30 seconds, and distances of 0.0, 0.5, 1.0, and 1.5 mm from the resin surface. The intensity of the Quick Light was measured as 510 mW/cm2 at 470 +/- 15 nm and the intensity of the argon laser was adjusted to 510 mW/cm2 before curing. Shear bond tests at a crosshead speed of 1.0 mm/min were performed after 24 hours of storage in water. The bond strengths obtained with the halogen lamp and the laser were not significantly different at the same exposure times and at 0.0 or 0.5 mm from the resin surface. The laser cured bond strengths did not decrease with increasing distance whereas there was a significant decrease in halogen bond strengths at distances greater than 0.5 mm for both resins. The use of the laser might provide a clinical advantage in cases where the curing light source cannot be brought into proximity to the surface of the resin.

  8. Effect of high power CO2 and Yb:YAG laser radiation on the characteristics of TIG arc in atmospherical pressure argon and helium

    Science.gov (United States)

    Wu, Shikai; Xiao, Rongshi

    2015-04-01

    The effects of laser radiation on the characteristics of the DC tungsten inert gas (TIG) arc were investigated by applying a high power slab CO2 laser and a Yb:YAG disc laser. Experiment results reveal that the arc voltage-current curve shifts downwards, the arc column expands, and the arc temperature rises while the high power CO2 laser beam vertically interacts with the TIG arc in argon. With the increase of the laser power, the voltage-current curve of the arc shifts downwards more significantly, and the closer the laser beam impingement on the arc to the cathode, the more the decrease in arc voltage. Moreover, the arc column expansion and the arc temperature rise occur mainly in the region between the laser beam incident position and the anode. However, the arc characteristics hardly change in the cases of the CO2 laser-helium arc and YAG laser-arc interactions. The reason is that the inverse Bremsstrahlung absorption coefficients are greatly different due to the different electron densities of the argon and helium arcs and the different wave lengths of CO2 and YAG lasers.

  9. Test beam studies of the TRD prototype filled with different gas mixtures based on Xe, Kr, and Ar

    Science.gov (United States)

    Celebi, E.; Brooks, T.; Joos, M.; Rembser, C.; Gurbuz, S.; Cetin, S. A.; Konovalov, S. P.; Tikhomirov, V. O.; Zhukov, K.; Fillipov, K. A.; Romaniouk, A.; Smirnov, S. Yu; Teterin, P. E.; Vorobev, K. A.; Boldyrev, A. S.; Maevsky, A.; Derendarz, D.

    2017-01-01

    Towards the end of LHC Run1, gas leaks were observed in some parts of the Transition Radiation Tracker (TRT) of ATLAS. Due to these leaks, primary Xenon based gas mixture was replaced with Argon based mixture in various parts. Test-beam studies with a dedicated Transition Radiation Detector (TRD) prototype were carried out in 2015 in order to understand transition radiation performance with mixtures based on Argon and Krypton. We present and discuss the results of these test-beam studies with different active gas compositions.

  10. Study of a Novel Concept for a Liquid Argon Calorimeter \

    CERN Multimedia

    2002-01-01

    % RD33 \\\\ \\\\ The development of a fast, highly granular and compact electromagnetic liquid argon calorimeter prototype is proposed as a generic R\\&D project for a novel concept of calorimetry in proton-proton and electron-positron collider detectors: the $^{\\prime$Thin Gap Turbine$^{\\prime}$ (TGT). The TGT calorimeter has a modular construction, is flexible in its longitudinal and transverse granularity, and offers a uniform energy response and resolution, independent of the production angle of incident particles. An important aspect of the project is the development of fast, radiation-hard front-end electronics which is operating in the cold.

  11. Liquid Argon TPC Signal Formation, Signal Processing and Hit Reconstruction

    Energy Technology Data Exchange (ETDEWEB)

    Baller, Bruce [Fermilab

    2017-03-11

    This document describes the early stage of the reconstruction chain that was developed for the ArgoNeuT and MicroBooNE experiments at Fermilab. These experiments study accelerator neutrino interactions that occur in a Liquid Argon Time Projection Chamber. Reconstructing the properties of particles produced in these interactions requires knowledge of the micro-physics processes that affect the creation and transport of ionization electrons to the readout system. A wire signal deconvolution technique was developed to convert wire signals to a standard form for hit reconstruction, to remove artifacts in the electronics chain and to remove coherent noise.

  12. Optical fiber read-out for liquid argon scintillation light

    CERN Document Server

    Csáthy, J Janicskó; Kratz, J; Schönert, S; Wiesinger, Ch

    2016-01-01

    In this paper we describe the performance of a light detector for Ar scintillation light made of wavelength-shifting (WLS) fibers connected to Silicon-Photomultipliers (SiPM). The setup was conceived to be used as anti-Compton veto for high purity germanium (HPGe) detectors operated directly in liquid Argon (LAr). Background suppression efficiencies for different radioactive sources were measured in a test cryostat with about 800 kg LAr. This work was part of the R\\&D effort for the GERDA experiment.

  13. Large Area Pico-second Photodetectors (LAPPD) in Liquid Argon

    Science.gov (United States)

    Dharmapalan, Ranjan; Lappd Collaboration

    2015-04-01

    The Large Area Pico-second Photodetector (LAPPD) project has recently produced the first working devices with a small form factor and pico-second timing resolution. A number of current and proposed neutrino and dark matter experiments use liquid argon as a detector medium. A flat photodetector with excellent timing resolution will help with background suppression and improve the overall sensitivity of the experiment. We present the research done and some preliminary results to customize the LAPPD devices to work in a cryogenic environment. Argonne National Laboratory (LDRD) and DOE.

  14. Dimerization of argon and the properties of its small clusters

    Science.gov (United States)

    Titov, S. V.; Serov, S. A.; Ostrovskii, G. M.

    2016-12-01

    Statistical thermodynamic means are used to study the bound state of a small cluster AN (2 ≤ N ≤ 5) of Lennard-Jones particles in a spherical cavity. The statistical sum is calculated by the Monte Carlo method. For the dimer, integration is reduced to quadratures. The integration region contains only phase space points corresponding to the bound cluster state. Dimerization constant 2A = A2 is calculated via the probability of finding a molecule in the bound state using the example of argon.

  15. The abundances of neon, sulfur, and argon in planetary nebulae

    Science.gov (United States)

    Beck, S. C.; Lacy, J. H.; Townes, C. H.; Aller, L. H.; Geballe, T. R.; Baas, F.

    1981-01-01

    New infrared observations of Ne II, Ar III, and S IV are used in optical observations of other ionization states of the considered elements to evaluate the abundances of neon, argon, and sulfur in 18 planetary nebulae. Attention is also given to one or more of the infrared lines in 18 other nebulae. It is pointed out that S IV was detected in approximately 90% of the observed objects, while Ar III was found in about 80%, and Ne II in roughly one-third. It is noted that optical observations typically include only a limited region of the nebula, while the infrared measurements frequently involve integration over the entire nebular image.

  16. Sulfur X-ray absorption fine structure in porous Li–S cathode films measured under argon atmospheric conditions

    Energy Technology Data Exchange (ETDEWEB)

    Müller, Matthias, E-mail: matthias.mueller@ptb.de [Physikalisch-Technische Bundesanstalt, Abbestr. 2-12, 10587 Berlin (Germany); Choudhury, Soumyadip [Leibniz-Institut für Polymerforschung, Hohe Strasse 6, 01069 Dresden (Germany); Technische Universität Dresden, Physical Chemistry of Polymeric Materials ,01062 Dresden (Germany); Gruber, Katharina [VARTA Micro Innovation GmbH, Stremayrgasse 9, 8010 Graz (Austria); Cruz, Valene B. [Universität Ulm, Institut für Elektrochemie, 89069 Ulm (Germany); Helmholtz-Institut Ulm (HIU), 89069 Ulm (Germany); Fuchsbichler, Bernd [VARTA Micro Innovation GmbH, Stremayrgasse 9, 8010 Graz (Austria); Jacob, Timo [Universität Ulm, Institut für Elektrochemie, 89069 Ulm (Germany); Helmholtz-Institut Ulm (HIU), 89069 Ulm (Germany); Koller, Stefan [VARTA Micro Innovation GmbH, Stremayrgasse 9, 8010 Graz (Austria); Stamm, Manfred [Leibniz-Institut für Polymerforschung, Hohe Strasse 6, 01069 Dresden (Germany); Technische Universität Dresden, Physical Chemistry of Polymeric Materials ,01062 Dresden (Germany); Ionov, Leonid [Leibniz-Institut für Polymerforschung, Hohe Strasse 6, 01069 Dresden (Germany); Beckhoff, Burkhard [Physikalisch-Technische Bundesanstalt, Abbestr. 2-12, 10587 Berlin (Germany)

    2014-04-01

    In this paper we present the first results for the characterization of highly porous cathode materials with pore sizes below 1 μm for Lithium Sulfur (Li–S) batteries by Near Edge X-ray Absorption Fine Structure (NEXAFS) spectroscopy. A novel cathode material of porous carbon films fabricated with colloidal array templates has been investigated. In addition, an electrochemical characterization has been performed aiming on an improved correlation of physical and chemical parameters with the electrochemical performance. The performed NEXAFS measurements of cathode materials allowed for a chemical speciation of the sulfur content inside the cathode material. The aim of the presented investigation was to evaluate the potential of the NEXAFS technique to characterize sulfur in novel battery material. The long term goal for the characterization of the battery materials is the sensitive identification of undesired side reactions, such as the polysulfide shuttle, which takes place during charging and discharging of the battery. The main drawback associated with the investigation of these materials is the fact that NEXAFS measurements can usually only be performed ex situ due to the limited in situ instrumentation being available. For Li–S batteries this problem is more pronounced because of the low photon energies needed to study the sulfur K absorption edge at 2472 eV. We employed 1 μm thick Si{sub 3}N{sub 4} windows to construct sealed argon cells for NEXAFS measurements under ultra high vacuum (UHV) conditions as a first step towards in situ measurements. The cells keep the sample under argon atmosphere at any time and the X-ray beam passes mainly through vacuum which enables the detection of the low energy X-ray emission of sulfur. Using these argon cells we found indications for the presence of lithium polysulfides in the cathode films whereas the correlations to the offline electrochemical results remain somewhat ambiguous. As a consequence of these findings one

  17. Performance of the ATLAS Hadronic End-Cap Calorimeter in Beam Tests

    CERN Document Server

    Dowler, B; Soukup, J; Vincter, M G; Cheplakov, A P; Datskov, V I; Fedorov, A; Javadov, N; Kalinnikov, V; Kakurin, S; Kazarinov, M; Kukhtin, V; Ladygin, E; Lazarev, A B; Neganov, A B; Pisarev, I; Serochkin, E; Shilov, S N; Shalyugin, A N; Usov, Yu; Bán, J; Bruncko, Dusan; Chytracek, R; Jusko, A; Kladiva, E; Strízenec, P; Gärtner, V; Hiebel, S; Hohlfeld, M; Jakobs, K; Köpke, L; Marschalkowski, E; Meder, D; Othegraven, R; Schäfer, U; Thomas, J; Walkowiak, W; Zeitnitz, C; Leroy, C; Mazini, R; Mehdiyev, R; Akimov, A; Blagov, M I; Komar, A; Snesarev, A A; Speransky, M N; Sulin, V; Yakimenko, M; Aderholz, M; Brettel, H; Cwienk, W D; Dulny, B; Fent, J; Fischer, A; Haberer, W; Huber, J; Huber, R; Karev, A; Kiryunin, A E; Kobler, T; Kurchaninov, L L; Laskus, H; Lindenmayer, M; Mooshofer, P; Oberlack, H; Salihagic, D; Schacht, P; Stenzel, H; Striegel, D; Tribanek, W; Chekulaev, S V; Denisov, S; Levitsky, M; Minaenko, A A; Mitrofanov, G Ya; Moiseev, A; Pleskatch, A; Sytnik, V V; Benoit, P; Hoyle, K; Honma, A; Maharaj, R; Oram, C J; Pattyn, E; Rosvick, M; Sbarra, C; Wellisch, H P; Wielers, M; Birney, P; Dobbs, M; Fincke-Keeler, M; Fortin, D; Hodges, T; Keeler, Richard K; Langstaf, R; Lefebvre, M; Lenckowski, M; McPherson, R A; O'Neil, D C; Forbush, D

    2002-01-01

    Modules of the ATLAS liquid argon Hadronic End-cap calorimeter (HEC) were exposed to beams of electrons, muons and pions in the energy range 6GeVbeam test setup are given. Results on the energy response and resolution are presented and compared with simulations. The ATLAS energy resolution for jets in the end-cap region is inferred and meets the ATLAS requirements.

  18. Performance of the ATLAS hadronic end-cap calorimeter in beam tests

    Energy Technology Data Exchange (ETDEWEB)

    Dowler, B.; Pinfold, J.; Soukup, J.; Vincter, M.; Cheplakov, A.; Datskov, V.; Fedorov, A.; Javadov, N.; Kalinnikov, V.; Kakurin, S.; Kazarinov, M.; Kukhtin, V.; Ladygin, E.; Lazarev, A.; Neganov, A.; Pisarev, I.; Serochkin, E.; Shilov, S.; Shalyugin, A.; Usov, Yu.; Ban, J.; Bruncko, D.; Chytracek, R.; Jusko, A.; Kladiva, E.; Strizenec, P.; Gaertner, V.; Hiebel, S.; Hohlfeld, M.; Jakobs, K.; Koepke, L.; Marschalkowski, E.; Meder, D.; Othegraven, R.; Schaefer, U.; Thomas, J.; Walkowiak, W.; Zeitnitz, C.; Leroy, C.; Mazini, R.; Mehdiyev, R.; Akimov, A.; Blagov, M.; Komar, A.; Snesarev, A.; Speransky, M.; Sulin, V.; Yakimenko, M.; Aderholz, M.; Brettel, H.; Cwienk, W.; Dulny, B.; Fent, J.; Fischer, A.; Haberer, W.; Huber, J.; Huber, R.; Karev, A.; Kiryunin, A.; Kobler, T.; Kurchaninov, L.; Laskus, H.; Lindenmayer, M.; Mooshofer, P.; Oberlack, H.; Salihagic, D.; Schacht, P. E-mail: phys@mppmn.mpg.de; Stenzel, H.; Striegel, D.; Tribanek, W.; Chekulaev, S.; Denisov, S.; Levitsky, M.; Minaenko, A.; Mitrofanov, G.; Moiseev, A.; Pleskatch, A.; Sytnik, V.; Benoit, P.; Hoyle, K.W.; Honma, A.; Maharaj, R.; Oram, C.J.; Pattyn, E.W.; Rosvick, M.; Sbarra, C.; Wellisch, H-P.; Wielers, M.; Birney, P.S.; Dobbs, M.; Fincke-Keeler, M.; Fortin, D.; Hodges, T.A.; Keeler, R.K.; Langstaff, R.; Lefebvre, M.; Lenckowski, M.; McPherson, R.; O' Neil, D.C.; Forbush, D.; Mockett, P.; Toevs, F.; Braun, H.M.; Thadome, J

    2002-04-11

    Modules of the ATLAS liquid argon Hadronic End-cap Calorimeter (HEC) were exposed to beams of electrons, muons and pions in the energy range 6{<=}E{<=}200 GeV at the CERN SPS. A description of the HEC and of the beam test setup are given. Results on the energy response and resolution are presented and compared with simulations. The ATLAS energy resolution for jets in the end-cap region is inferred and meets the ATLAS requirements.

  19. Modified quadrupole mass analyzer RGA-100 for beam plasma research in forevacuum pressure range

    Energy Technology Data Exchange (ETDEWEB)

    Zolotukhin, D. B.; Tyunkov, A. V. [Tomsk State University of Control Systems and Radioelectronics, 40 Lenin Ave., Tomsk 634050 (Russian Federation); Yushkov, Yu. G., E-mail: yuyushkov@gmail.com [Tomsk State University of Control Systems and Radioelectronics, 40 Lenin Ave., Tomsk 634050 (Russian Federation); Tomsk Polytechnic University, 30 Lenin Ave., Tomsk 634050 (Russian Federation); Oks, E. M. [Tomsk State University of Control Systems and Radioelectronics, 40 Lenin Ave., Tomsk 634050 (Russian Federation); Institute of High Current Electronics SB RAS, 2/3, Akademichesky Ave., Tomsk 634055 (Russian Federation)

    2015-12-15

    The industrial quadrupole RGA-100 residual gas analyzer was modified for the research of electron beam-generated plasma at forevacuum pressure range. The standard ionizer of the RGA-100 was replaced by three electrode extracting unit. We made the optimization of operation parameters in order to provide the maximum values of measured currents of any ion species. The modified analyzer was successfully tested with beam plasma of argon, nitrogen, oxygen, and hydrocarbons.

  20. A quantitative comparison between electrocoagulation and chemical coagulation for boron removal from boron-containing solution

    Energy Technology Data Exchange (ETDEWEB)

    Yilmaz, A. Erdem [Atatuerk University, Faculty of Engineering, Department of Environmental Engineering, 25240 Erzurum (Turkey)], E-mail: aerdemy@atauni.edu.tr; Boncukcuoglu, Recep [Atatuerk University, Faculty of Engineering, Department of Environmental Engineering, 25240 Erzurum (Turkey); Kocakerim, M. Muhtar [Atatuerk University, Faculty of Engineering, Department of Chemical Engineering, 25240 Erzurum (Turkey)

    2007-10-22

    This paper provides a quantitative comparison of electrocoagulation and chemical coagulation approaches based on boron removal. Electrocoagulation process delivers the coagulant in situ as the sacrificial anode corrodes, due to a fixed current density, while the simultaneous evolution of hydrogen at the cathode allows for pollutant removal by flotation. By comparison, conventional chemical coagulation typically adds a salt of the coagulant, with settling providing the primary pollutant removal path. Chemical coagulation was carried out via jar tests using aluminum chloride. Comparison was done with the same amount of coagulant between electrocoagulation and chemical coagulation processes. Boron removal obtained was higher with electrocoagulation process. In addition, it was seen that chemical coagulation has any effect for boron removal from boron-containing solution. At optimum conditions (e.g. pH 8.0 and aluminum dose of 7.45 g/L), boron removal efficiencies for electrocoagulation and chemical coagulation were 94.0% and 24.0%, respectively.