WorldWideScience

Sample records for approval letter bk090041

  1. LETTERS

    Institute of Scientific and Technical Information of China (English)

    2004-01-01

    At the request of you, our readers, this year we are introducing a "Letters to the Editor" column. We value your comments, positive and negative, on our layout, content and pictures and will make continuous efforts to improve our magazine. We welcome your comments and views on all aspects of China. [We reserve the right to edit for content, clarity or length.]If your letter or e-mail is published, you receive a gift!

  2. LETTERS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Dear Editor, I am a loyal reader of your magazine. I read Issue No.9 (March 2, 2006) and was deeply impressed by the articles on tobacco. Tobacco is indeed a big problem in China. Well, I would like to introduce, through your letters page, an association closely related to tobacco control. It is called Green Breathing Association, a student organization in Xiamen University (probably the first one of its kind in China). The mission of Green Breathing is to promote the public awareness of tobac-

  3. Letters

    Science.gov (United States)

    2001-01-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE, UK. Contents: Maths for physics? Help! Fire! Energy and mass Maths for physics? As a maths graduate working as a university research associate I should be well qualified to support my daughter, who has just started AS-level physics, with the maths she needs for the course. There seems to be little integration between the maths and physics departments, so that maths needed for physics has not yet been covered in maths lessons. This is a problem I remember from my own school days, but the shorter timescale and modular nature of the AS and A2 levels means that it is essential that this mismatch of knowledge is resolved now. I would like to know whether physics teachers in the UK have encountered this problem and whether there is a deficiency in the maths syllabus in relation to the requirements of the AS and A2 levels in Physics or whether this is a problem peculiar to my daughter's school. Eleanor Parent of A-level student, Sheffield, UK Help! Fire! Is there a crisis in physics education? Is physics didactics coming to an end? Yes and no. Being a delegate from Norway at the on-going conference Physics on Stage (6-10 November 2000) at CERN in Geneva, I have had the opportunity to discuss this with people from all over Europe. Yes, there is a crisis. (Look at the proceedings for details on this.) I'd like to take a broader look at this situation. Like Hari Seldon in Isaac Asimov's Foundation Trilogy, I believe that there is nothing like a real crisis to get things going... Famous is the quote from the American Patent Office around 1890: 'Everything has been invented that could be invented'. Fortunately, this spurred action. The Michelson and Morley experiment heralded a most exciting period for physics. Just a cosmic blink later we put a person on the Moon. Coming back to the crisis - I am certain that in the near future we will see an interesting development

  4. Letters

    Science.gov (United States)

    2001-07-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE, UK. Contents: Alternative view of education in Zambia Pedantry or compromise Alternative view of education in Zambia I have just read the 'On the Map' report of the International School of Lusaka with very mixed feelings (Physics Education, March 2001). I have recently spent some time in Zambia, in Lusaka, and share Sue Pears' love for the country and the Zambians. The ISL is indeed a good, prestigious school, similar to International Schools in many other countries. But, as in most other developing countries, there is enormous variation between the different types of schooling, and the ISL is at one end of the spectrum. Most schools in Zambia are less favoured. Zambia is a wonderful, beautiful country full of the most friendly and resourceful people I know. It is also a very poor country. It is a country of enormous contrasts and its schools reflect that variation. It has a tiny, affluent 'middle' class of professionals, politicians, businessmen, employees of international businesses and NGOs—nearly all paid from overseas budgets. It has an enormous majority of poor folk, cheerfully living in very basic conditions but sharing their lives in extended families without complaint. The government is virtually bankrupt, and consequently those paid by the government—teachers, police, nurses etc—get a pittance. The wage for a teacher in a typical school is #20 per month (compared to a typical teacher in the UK who gets 100 times more, about #2000 per month). The GNP in Zambia is about 1 per day per person, and this has to pay for all the schools, hospitals, police, and the civic infrastructure that we take so much for granted (the GNP in UK is about 60 per day per person). Consequently most state schools do not have resources; they have a classroom and a teacher but little else. What resources the school has will be paid for by the school fees that every

  5. Letters

    Science.gov (United States)

    2001-03-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE Contents: Force on a pendulum Sound slows down Bond is back Force on a pendulum The simple pendulum has been used by several educationalists for investigating the patterns of thinking among students and their observations that Aristotelian thinking persists among students at college level. I had also considered the simple pendulum in my 1985 letter in Physics Today [1], so I was interested to read the test given by Lenka Czudková and Jana Musilová [2]. When students were asked to draw net forces acting on the particle at various positions, 31.9% of students believed that the net force was tangential to the particle's path the whole time. To me this is no surprise because in our derivation of the equation for the period of a simple pendulum we assume that the unbalanced sine component provides the restoring force for the harmonic motion of the bob. Of course, Czudková and Musilová's question asked students for the net force on the particle, not the component. The student's answer fits well with the logic of the equilibrium of forces and the parallelogram law. Lastly, let me bring out the similarity between the student's answer and the thinking of George Gamow. He used to call positrons 'donkey' electrons because of their displacement against the applied force, before Paul Dirac termed them positrons. Victor Weisskeptf told me this anecdote in a letter in May 1982. References [1] Sathe D 1985 Phys. Today 38 144 [2] Czudková L and Musilová J 2000 Phys. Educ. 35 428 Dileep V Sathe Dadawala Jr College, Pune, India Sound slows down Without wanting to stir up more trouble amongst the already muddy waters of Physics teaching, consider how many times you have heard (or, more worryingly, read) this: 'Sound waves travel faster in a denser material' But...The velocity of simple longitudinal waves in a bulk medium is given by v = (K/ρ)1/2 where K is

  6. Letters

    Science.gov (United States)

    2001-09-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE, UK. Contents: M-set as metaphor The abuse of algebra M-set as metaphor 'To see a World in a Grain of Sand And a Heaven in a Wild Flower Hold Infinity in the palm of your hand And Eternity in an hour' William Blake's implied relativity of spatial and temporal scales is intriguing and, given the durability of this worlds-within-worlds concept (he wrote in 1803) in art, literature and science, the blurring of distinctions between the very large and the very small must strike some kind of harmonious chord in the human mind. Could this concept apply to the physical world? To be honest, we cannot be absolutely sure. Most cosmological thinking still retains the usual notions of a finite universe and an absolute size scale extending from smallest to largest objects. In the boundless realm of mathematics, however, the story is quite different. The M-set was discovered by the French mathematician Benoit Mandelbrot in 1980, created by just a few simple lines of computer code that are repeated recursively. As in Blake's poem, this 'world' has no bottom we have an almost palpable archetype for the concept of infinity. I would use the word 'tangible', but one of the defining features of the M-set is that nowhere in the labyrinth can one find a surface smooth enough for a tangent. Upon magnification even surfaces that appeared to be smooth explode with quills and scrolls and lightning bolts and spiral staircases. And there is something more, something truly sublime. Observe a small patch with unlimited magnifying power and, as you observe the M-set on ever-smaller scales, down through literally endless layers of ornate structure, you occasionally come upon a rapidly expanding cortex of dazzling colour with a small black structure at its centre. The black spot appears to be the M-set itself! There is no end to the hierarchy, no bottom-most level, just endless recursive

  7. Letters

    Science.gov (United States)

    2001-05-01

    The Editor welcomes letters, by e-mail to ped@iop.org or by post to Dirac House, Temple Back, Bristol BS1 6BE, UK. Contents: Quantum uncertainties Reflections in a plastic box A brief history of quantum physics Correction Grammar and gender Quantum uncertainties Whilst I enjoyed Gesche Pospiech's article ('Uncertainty and complementarity: the heart of quantum physics' 2000 Phys. Educ. 35 393 9) I would like to expand on two comments he makes. Firstly the author claims that QM is linear, and a consequence of this is that any two superimposed states form an admissible third state. This is rather too sweeping, as it is true only for degenerate states. Otherwise quantum mechanics would allow a continuum of energies between states by a simple admixture of levels. The proof of this statement is trivial. For a Hamiltonian H and two orthogonal wavefunctions, ψ1 and ψ2 with energies E1 and E2 then (ψ1 + ψ2) is not an eigenfunction of that Hamiltonian as H(ψ1 + ψ2) = E1ψ1 + E2ψ2 ≠ E(ψ1 + ψ2) for any value of E, unless E1 = E2. Secondly Pospiech states that quantum objects show wave- or particle-like behaviour, depending on the measuring apparatus, and that occasionally experiments (such as Taylor's) reveal both. I would contest the validity of this type of thinking. All experiments on quantum objects reveal both types of behaviour—even ones which simply show straight line motion of photons. What is important, in addition, is our interpretation of the results. It takes an understanding of QED, for example, to see that an experiment which otherwise shows particle behaviour is, in fact, showing quantum behaviour. More contentiously though I would suggest that detection apparatus is incapable of detecting anything other than particles. Wave-like behaviour is revealed only by an analysis of the paths the particle could have taken. In other words, the interference of continuous fields sometimes predicts the same results when the detection is averaged over many events

  8. 9 CFR 316.7 - Marking devices not to be false or misleading; style and size of lettering; approval required.

    Science.gov (United States)

    2010-01-01

    ... figures thereon shall be of such style and type as will make a clear and legible impression. All markings... misleading; style and size of lettering; approval required. 316.7 Section 316.7 Animals and Animal Products... AND THEIR CONTAINERS § 316.7 Marking devices not to be false or misleading; style and size...

  9. Searching for approval. Tax-exempt hospitals, systems may find some relief through FHLB letters of credit in last week's housing aid bill.

    Science.gov (United States)

    Evans, Melanie

    2008-08-01

    The bill to aid homeowners that Congress passed last week also offered a gift for tax-exempt healthcare borrowers. The law allows the Federal Home Loan Banks to back tax-exempt bonds with letters of credit, thus letting borrowers benefit from those banks' credit strength. But don't expect the floodgates to open. "Banks are preserving their capital for less risky endeavors," says Kelly Arduino, left, of Wipfli.

  10. Letter to jane addams.

    Science.gov (United States)

    Bloom, M

    1995-06-01

    This letter, written to one of the founding figures in social work, draws parallels between primary prevention at the beginning and the end of the twentieth century. As expected, the letter remains unanswered.

  11. Drugs Approved for Bladder Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for bladder cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  12. Drugs Approved for Breast Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for breast cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  13. Drugs Approved for Pancreatic Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for pancreatic cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  14. Van: An Open Letter

    Science.gov (United States)

    Tieman, John Samuel

    2011-01-01

    This essay is an open letter from a classroom teacher to a concerned citizen. The letter lists a variety of problems caused largely by standardization and the more corrosive effects of positivism. Many of these problems are unknown to those outside the immediate school setting. While the letter focuses on a specific setting, an inner city school…

  15. Heartland Winthrop Approval

    Science.gov (United States)

    This May 19, 2016 letter from EPA approves the petition from Heartland Corn Products regarding non-grandfathered ethanol produced through a dry mill process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the RFS program.

  16. FHR Iowa Falls Approval

    Science.gov (United States)

    This October 22, 2015, letter from EPA approves the petition from Flint Hills Resources, LLC, regarding non-grandfathered ethanol produced through the FHR Iowa Falls Process, qualifying under the Clean Air Act for renewable fuel (D-code 6) RINs under the R

  17. The Business Letter.

    Science.gov (United States)

    Nederland Independent School District, TX.

    GRADES OR AGES: Grades 9-12. SUBJECT MATTER: Business. ORGANIZATION AND PHYSICAL APPEARANCE: This guide, designed for direct student use, indicates the parts of a business letter, a placement guide, and steps for typing letters. Worksheets and illustrations indicate forms of block and indented styles; open, closed, and mixed punctuation; the…

  18. Letter of Map Revision

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  19. Letters from Our Readers

    Institute of Scientific and Technical Information of China (English)

    1993-01-01

    Since the first publication of Cultural Exchang-China& World in October 1992,we have received a unmber of verykind letters from Chinese and foreign readers giving support andencouagement to this magazine.We would like to take thisopportunity to thank them all and to invite others to write in as well,especially if they have suggestions or criticisms to make.Thefollowing are letters from two of our overseas readers.

  20. Drugs Approved for Colon and Rectal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for use in colon cancer and rectal cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters.

  1. Temporal processing deficits in letter-by-letter reading.

    Science.gov (United States)

    Ingles, Janet L; Eskes, Gail A

    2007-01-01

    Theories of the cognitive impairment underlying letter-by-letter reading vary widely, including prelexical and lexical level deficits. One prominent prelexical account proposes that the disorder results from difficulty in processing multiple letters simultaneously. We investigated whether this deficit extends to letters presented in rapid temporal succession. A letter-by-letter reader, G.M., was administered a rapid serial visual presentation task that has been used widely to study the temporal processing characteristics of the normal visual system. Comparisons were made to a control group of 6 brain-damaged individuals without reading deficits. Two target letters were embedded at varying temporal positions in a stream of rapidly presented single digits. After each stream, the identities of the two letters were reported. G.M. required an extended period of time after he had processed one letter before he was able to reliably identify a second letter, relative to the controls. In addition, G.M.'s report of the second letter was most impaired when it immediately followed the first letter, a pattern not seen in the controls, indicating that G.M. had difficulty processing the two items together. These data suggest that a letter-by-letter reading strategy may be adopted to help compensate for a deficit in the temporal processing of letters.

  2. 75 FR 62439 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving a...

    Science.gov (United States)

    2010-10-08

    ...-2010-043] Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving..., 2010. I. Introduction On August 6, 2010, the Financial Industry Regulatory Authority, Inc. (``FINRA..., 2010 (``Wiesenberg Letter''); Letter from Manisha Kimmel, Executive Director, Financial...

  3. Letters in this Issue

    Science.gov (United States)

    1998-01-01

    Reforming the General Chemistry Textbook individual letters by Edward T. Samulski; Stephen J. Hawkes; Stephen J. Fisher; J. Stephen Hartman; A. R. H. Cole; Stanley Pine, Ronald Archer, and Herbert Kaesz; Jimmy Reeves; Robert Hill; and Brock Spencer, C. Bradley Moore and Nedah Rose. Re: article by R. J. Gillespie The author replies

  4. Letter to the Editor

    Directory of Open Access Journals (Sweden)

    Pamela Ann Marshall

    2015-12-01

    Full Text Available A letter to the Editor alerting the ASM education community to the passing of Dr. Joseph P. Caruso, influential colleague and co-author of an article included in the scientific citizenship-themed issue of the Journal of Microbiology & Biology Education (JMBE.

  5. The Scarlet Letter

    NARCIS (Netherlands)

    Hawthorne, Nathaniel

    2005-01-01

    The Scarlet Letter is the story of three New England settlers at odds with the Puritan society in which they live. Roger Chillingworth, an ageing scholar, arrives in New England after two years' separation from his wife Hester to find her on trial for adultery. She refuses to reveal her lover's iden

  6. The Fuzzy Scarlet Letter

    Science.gov (United States)

    Pallas, Aaron M.

    2012-01-01

    Critics of the public release of teacher evaluation scores sometimes liken these ratings to the scarlet letter worn by Hester Prynne in Nathaniel Hawthorne's classic novel. The comparison is apt. But public school teachers who are subjected to public shaming because of their students' test scores can rarely expect the opportunities for redemption…

  7. Lincoln's Letter to Siam.

    Science.gov (United States)

    Alexander, Mary; Childress, Marilyn

    1980-01-01

    Focuses on the problem of the U.S. president receiving gifts from foreign dignitaries. The reproducible letter from President Lincoln to King Rama IV of Siam in which he accepts two gifts and graciously declines proffered elephants serves as center for discussion of the problem. Suggestions for teaching and a crossword puzzle are included. (KC)

  8. On The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    徐丹

    2016-01-01

    Reading The Scarlet Letter, one is mostly impressed by the spirit of The Bible the story depicted. The book chiefly discusses sin and how to atone for it. Hester Prynne is the heroine of the fiction. This paper researches her fate to illustrate the influence of The Bible to Hawthorne.

  9. Symbolism in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    王忠杰

    2007-01-01

    Nathaniel Hawthorne is the greatest American romantic novelist during the nineteenth century. This paper researches the symbolism in his masterpiece The Scarlet Letter from the aspect of the symbolic meaning of the scarlet letter.

  10. Letters to a Young Writer.

    Science.gov (United States)

    Wright, C. D.; Schulman, Grace

    2001-01-01

    Presents two letters to a young writer, modeled on the influential "Letters to a Young Poet" by Rainer Maria Rilke. Notes the first letter situates itself when a young writer first turns toward poetry; and the second addresses the relationship between mentorship and the imagination, questioning the right of any writer to presume to guide the…

  11. Drugs Approved for Hodgkin Lymphoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for Hodgkin lymphoma. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  12. Drugs Approved for Multiple Myeloma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for multiple myeloma and other plasma cell neoplasms. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  13. Drugs Approved for Myeloproliferative Neoplasms

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for myeloproliferative neoplasms. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  14. A red-letter day !

    CERN Document Server

    2008-01-01

    Today is a red-letter day for the LHC and CERN as a beam of protons has travelled around the LHC ring for the very first time! The start of LHC operation marks the end of a long period in which you have given your all, and this first particle beam circulating in the accelerator now paves the way for discoveries that will open up a whole new field of knowledge. The history of the LHC began in 1984 with a debate on the possible objectives of a future accelerator, based on the state of our knowledge at that time. The CERN Council then approved the single-stage construction of the LHC in 1996, giving the go-ahead for the work that has now reached completion. For the past twelve years, physicists, engineers and technicians from CERN and its associated institutes have been engaged in constructing the three pillars of the LHC: the accelerator (including the upgrade of the existing accelerator chain), the four experiments, and the computing ...

  15. A Letter to Alien

    Institute of Scientific and Technical Information of China (English)

    邱政榜

    2012-01-01

    Dear Alien, 1 am sorry to hear that you have some problems. I hear you argued with your best friend. 1 think you could call him up or go to his home. You could write him a letter. And you could tell him you are sony. Or maybe you could give him a ticket to a ball game. I am sure you will get on well with him again.

  16. The Danish letters

    DEFF Research Database (Denmark)

    Beier, Sofie; Ejlers, Steen

    2011-01-01

    The talk will focus on Danish type designers and their work on Æ (AE), Ø (Oslash) and Å (Aring). These 'anomalies' found in the Danish written language, often causes difficulties for type designers. The counters of Ø/ø sometimes appear overcrowded, the uppercase Æ can result in an uncomfortably o......' attempt to create the optimal variation of these letters, we will give a brief introduction to the Danish typography tradition ranging from the early 20th Century and up until today....

  17. A comparison of letter and digit processing in letter-by-letter reading.

    Science.gov (United States)

    Ingles, Janet L; Eskes, Gail A

    2008-01-01

    The extent to which letter-by-letter reading results from a specific orthographic deficit, as compared with a nonspecific disturbance in basic visuoperceptual mechanisms, is unclear. The current study directly compared processing of letters and digits in a letter-by-letter reader, G.M., using a rapid serial visual presentation (RSVP) task and a speeded matching task. Comparisons were made to a group of six brain-damaged individuals without reading deficits. In the RSVP task, G.M. had increased difficulty reporting the target identities when they were letters, as compared with digits. Although this general pattern was also evident in the control group, the magnitude of the letter-digit accuracy difference was greater in G.M. Similarly, in the matching task, G.M. was slower to match letters than digits, relative to the control group, although his response times to both item types were increased. These data suggest that letter-by-letter reading, at least in this case, results from a visuoperceptual encoding deficit that particularly affects letters, but also extends to processing of digits to a lesser extent. Results are consistent with the notion that a left occipitotemporal area is specialized for letter processing with greater bilaterality in the visual processing of digits.

  18. Letters to the Editor

    Science.gov (United States)

    1998-03-01

    All the Letters to the Editor in this issue are in the same PostScript or PDF file. Contents Comment on `Magnetic and electric field strengths of high voltage power lines and household appliances' José Luis Giordano Dept. de Ciencia y Tecnología de Materiales y Fluidos, CPSI, Universidad de Zaragoza, Spain Twins paradox S R Carson Norton College, Malton, North Yorkshire, UK On alternative ways of finding the ratio of specific heats of gases Tomas Ficker Physics Department, Technical University of Brno, Czech Republic

  19. Checklist Evaluation for Teaching Business Letters.

    Science.gov (United States)

    Javed, M. Latif

    1981-01-01

    Offers a checklist for use in evaluating business letters written by students. Contends that the checklist can simplify paper checking, objectify grading, help students better prepare their letter assignments, and facilitate their understanding of letter writing principles. (FL)

  20. How to Write a Business Letter

    Institute of Scientific and Technical Information of China (English)

    N·J·斯特克

    2004-01-01

    @@ Generally speaking, there are two kinds of letters, business letters and personal letters. By "business" we do not mean buying, selling, or exchanging goods with people or companies, although it can mean that, but important matters we have to discuss or deal with. A business letter may be a recommendation, a job/college application, an inquiry, an answer, an invitation, a complaint, etc. In other words, all letters that are not "personal"are "business" letters.

  1. Letter from the Friends Chairman

    Science.gov (United States)

    ... Home Current Issue Past Issues Letter from the Friends Chairman Past Issues / Fall 2006 Table of Contents ... FNLM Chairman Paul Rogers converse at a recent Friends function at the National Library of Medicine. Photo ...

  2. The Style of Business Letters

    Institute of Scientific and Technical Information of China (English)

    Li Kai

    2008-01-01

    This study explores the application of Systemic Functional Granunar (SFG) to the analysis of English Business Letters (EBL). With China's opening up to the outside, especially its entrance into WTO, international business is becoming more and more popular. Most of the transactions in international business are discussed in detail through airmail letters, telegrams, telexes, faxes or E-mails.As a world language, English is used widely in the negotiation of international businesses. Writing a piece of effective English Business Letter is of great importance. As a medium between the business partners, EBL affects the interaction and negotiation between them. This article is intended to seek the linguistic characteristics of business letters and prove that the theories of SFG can be used to analyze EBL discourse and they are actually effective.

  3. Unit 2: Application Letters & The Job Interview

    OpenAIRE

    Aleson Carbonell, Marian

    2007-01-01

    Unit 2a_ Letters of Application and the CV: Reading the employment section. Unit 2b_Letters of Application and the CV:Writing Letters and the Job Hunting Process. Unit 2c_ Letters of Application and the CV: The Job Interview.

  4. Essay: Physical Review Letters; Sam Goudsmit's Vision.

    Science.gov (United States)

    Adair, Robert K

    2008-01-18

    Sam Goudsmit implemented his vision of converting the Letters section of Physical Review into a distinct journal fifty years ago. Physical Review Letters was designed to publish "only papers that really deserve rapid communication." The new journal became so successful with physicists throughout the world that Physical Review Letters now publishes 3500 Letters per year.

  5. Letter Writing: A Tool for Counselor Educators

    Science.gov (United States)

    Hoffman, Rachel M.

    2008-01-01

    Letter writing is an integral component of narrative therapy practice. In addition to the benefits of letter writing in counseling practice, letter writing may hold interesting possibilities for use in counselor education. This article provides a brief review of the benefits of letter writing in counseling practice and discusses the potential use…

  6. Symbolism in the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    苑文良

    2005-01-01

    A famous writer in American Renaissance, Nathaniel Hawthorne was deeply influenced by three thoughts, Puritanism consciousness, transcendental philosophy and transcendentalism .Novel The Scarlet Letter is Hawthorne's most remarkable masterpiece. It thoroughly response to people's spirit wreck of Puritanism and unbridled pursuit for happy life. Meanwhile, The Scarlet Letter also makes Nathanael Hawthorne known all around the world. Hawthorne uses the symbolism so skilfful that it enhances the artistic effects of his work greatly. This paper researches the symbolism in this novel from the following aspects: the changing symbolic meaning of the scarlet letter, the names of the major characters and many objects that are described in the novel to make the symbolism clear to the readers.

  7. Symbolism in the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    苑文良

    2005-01-01

    A famous writer in American Renaissance, Nathaniel Hawthorne was deeply influenced by three thoughts, Puritanism consciousness, transcendental philosophy and transcendentalism .Novel The Scarlet Letter is Hawthorne's most remarkable masterpiece. It thoroughly response to people's spirit wreck of Puritanism and unbridled pursuit for happy life. Meanwhile, The Scarlet Letter also makes Nathaniel Hawthorne known all around the world. Hawthorne uses the symbolism so skillful that it enhances the artistic effects of his work greatly. This paper researches the symbolism in this novel from the following aspects: the changing symbolic meaning of the scarlet letter, the names of the major characters and many objects that are described in the novel to make the symbolism clear to the readers.

  8. THE POWER OF LOWERCASE LETTERS IN READING

    Directory of Open Access Journals (Sweden)

    Firdevs GÜNEŞ

    2012-06-01

    Full Text Available Today, the most superior way of obtaining knowledge is reading. Reading gives direction to the individual's language, cognitive, social skills and future. For this reason, great importance is given to the teaching of reading. The teaching of reading is carried out based on two basic skills including word recognition and comprehension. In the word recognition process, appearance of the letters the shapes of the wordswritten in uppercase or lowercase letters are effective. Brain research reveal that the words written in small letters more quickly recognized and understood. Based on the recognition of words written in capital letters, small letters become stronger and they are recognised easier than the capital letters. For this reason, a text written in small letter is read more quickly than in capital letters. In addition, text in lowercase letters makes to examine all the details of the text, in-depth awareness and understanding. Small letters are in the process of visual recognition, attention, and remember the rule affects reading, seeing, understanding, and accelerates the configuration tasks in mind. This situation makes the use of lowercase letters in advertising. The advertising in small letters and logos were more easily recognized and remembered. Therefore, in order to increase strength of association big companies and brands, are used lowercase letters. In reading activities taking these results into well known and necessary precautions should be taken about lowercase letters.

  9. Curriculum Vitae and Related Letters.

    Science.gov (United States)

    Peterson, Sharyl Bender

    This booklet, which was developed by a college career center, explains the purpose of and procedures for writing curriculum vitae (CV) and related letters. The following topics are covered: when a CV is appropriate, points to consider when writing a CV, items usually included, possible sections to include in a CV, and steps in writing cover…

  10. Electronic Discharge Letter Mobile App

    NARCIS (Netherlands)

    Lezcano, Leonardo; Triana, Michel; Ternier, Stefaan; Hartkopf, Kathleen; Stieger, Lina; Schroeder, Hanna; Sopka, Sasa; Drachsler, Hendrik; Maher, Bridget; Henn, Patrick; Orrego, Carola; Marcus, Specht

    2014-01-01

    The electronic discharge letter mobile app takes advantage of Near Field Communication (NFC) within the PATIENT project and a related post-doc study. NFC enabled phones to read passive RFID tags, but can also use this short-range wireless technology to exchange (small) messages. NFC in that sense co

  11. Effects of stimulus duration and inter-letter spacing on letter-in-string identification.

    Science.gov (United States)

    Marzouki, Yousri; Grainger, Jonathan

    2014-05-01

    Effects of stimulus duration and inter-letter spacing were studied in a letter-in-string identification paradigm. Participants were shown strings of 5 random consonants (e.g., PGKDM) centered on fixation and were asked to identify the letter that had appeared at a post-cued location. Stimulus duration was manipulated in Experiment 1 (13 ms-91 ms), and inter-letter spacing manipulated in Experiment 2 (for a fixed stimulus duration of 26 ms). We contrasted performance to outer-letters (positions 1 and 5) with non-central inner letters (positions 2 and 4), the first-letter (position 1) with the final letter (position 5), and the central-letter (position 3) with the other inner letters (positions 2 and 4). The outer-letter advantage and the first-letter advantage were present throughout the entire range of exposure durations, whereas the central-letter advantage increased with longer exposures. On the other hand, increased spacing reduced both the outer-letter advantage and the first-letter advantage, whereas it led to a greater central-letter advantage. Changes in acuity and crowding as a function of stimulus exposure and inter-letter spacing, can account for this pattern of results.

  12. Letter to President [Lostwood National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Secretary of the Interior to the President regarding the establishment of the Lostwood Wilderness area. The letter discusses the...

  13. The Presentation of Courtesy in Business Letter

    Institute of Scientific and Technical Information of China (English)

    刘文君

    2013-01-01

    Nowadays the tendency of economic globalization in the world brings about increasingly closer international trade cooperation. The business letter has been an important communicative tool in the international trade. A polite business letter could promote the trade and help achieve the business cooperation. Therefore the presentation of courtesy in the business letter is of great significance. This paper presents a study of the courtesy in the business letter from the lexical aspect.

  14. Beyond Zebra: Preschoolers' Knowledge about Letters.

    Science.gov (United States)

    Treiman, Rebecca; Richmond-Welty, E. Daylene; Tincoff, Ruth

    1997-01-01

    Argues that an important type of child knowledge about letters is knowledge of the phonological structure of the letters' names in English. Concludes that learning the alphabet forms the basis for generalizations about the structure of letter names. (22 references) (Author/CK)

  15. Michelangelo, a Tireless Letter Writer

    Directory of Open Access Journals (Sweden)

    Adelin Charles Fiorato

    2014-04-01

    Full Text Available A titan of artistic creation, the sculptor-painter-architect Michelangelo was also a tireless letter writer. Five hundred and eighteen of his letters have reached us, stretching from his youth to the eve of his death, but we know that many others have been lost. Written in a kind of familiar Florentine and in a style of minimalist ‘realism’ – which does not prevent the presence of either impetuous polemical flights or pages of literary indulgence – these letters deal mainly with everyday subjects: day-by-day relationships, either endearing or resentful, with his relatives, financial or property matters and, above all, the marriage problems which concerned his nephew Leonardo, the sole heir of the family. But one also discovers in them the artist’s warm feelings of friendship and love, his poetic and aesthetic exchanges, his relationships, often conflictual, with his fellow-artists and patrons as well as his reflections on old age and death. All in all, these letters represent a documentary chronicle of a Florentine bourgeois family and the technical hassle of an entrepreneur’s activity. If, on the one hand, the Carteggio does not shed light either on Michelangelo’s conception of art or the way in which he realized his works, on the other it illustrates certain latent aspects of his projects, as well as of his personality, which was at the same time melancholy and aggressive, surprisingly whole and manifold. This luxuriant correspondence presents, so to speak, a ‘genetic’ interest, since it reveals the hidden face of the brilliant conceiver and creator, of the artist and entrepreneur struggling with the obstacles whose overcoming makes creation possible. 

  16. Spatio-temporal properties of letter crowding

    Science.gov (United States)

    Chung, Susana T. L.

    2016-01-01

    Crowding between adjacent letters has been investigated primarily as a spatial effect. The purpose of this study was to investigate the spatio-temporal properties of letter crowding. Specifically, we examined the systematic changes in the degradation effects in letter identification performance when adjacent letters were presented with a temporal asynchrony, as a function of letter separation and between the fovea and the periphery. We measured proportion-correct performance for identifying the middle target letter in strings of three lowercase letters at the fovea and 10° in the inferior visual field, for a range of center-to-center letter separations and a range of stimulus onset asynchronies (SOA) between the target and flanking letters (positive SOAs: target preceded flankers). As expected, the accuracy for identifying the target letters reduces with decreases in letter separation. This crowding effect shows a strong dependency on SOAs, such that crowding is maximal between 0 and ∼100 ms (depending on conditions) and diminishes for larger SOAs (positive or negative). Maximal crowding does not require the target and flanking letters to physically coexist for the entire presentation duration. Most importantly, crowding can be minimized even for closely spaced letters if there is a large temporal asynchrony between the target and flankers. The reliance of letter identification performance on SOAs and how it changes with letter separations imply that the crowding effect can be traded between space and time. Our findings are consistent with the notion that crowding should be considered as a spatio-temporal, and not simply a spatial, effect. PMID:27088895

  17. Spatio-temporal properties of letter crowding.

    Science.gov (United States)

    Chung, Susana T L

    2016-01-01

    Crowding between adjacent letters has been investigated primarily as a spatial effect. The purpose of this study was to investigate the spatio-temporal properties of letter crowding. Specifically, we examined the systematic changes in the degradation effects in letter identification performance when adjacent letters were presented with a temporal asynchrony, as a function of letter separation and between the fovea and the periphery. We measured proportion-correct performance for identifying the middle target letter in strings of three lowercase letters at the fovea and 10° in the inferior visual field, for a range of center-to-center letter separations and a range of stimulus onset asynchronies (SOA) between the target and flanking letters (positive SOAs: target preceded flankers). As expected, the accuracy for identifying the target letters reduces with decreases in letter separation. This crowding effect shows a strong dependency on SOAs, such that crowding is maximal between 0 and ∼100 ms (depending on conditions) and diminishes for larger SOAs (positive or negative). Maximal crowding does not require the target and flanking letters to physically coexist for the entire presentation duration. Most importantly, crowding can be minimized even for closely spaced letters if there is a large temporal asynchrony between the target and flankers. The reliance of letter identification performance on SOAs and how it changes with letter separations imply that the crowding effect can be traded between space and time. Our findings are consistent with the notion that crowding should be considered as a spatio-temporal, and not simply a spatial, effect.

  18. A bread-and-butter letter

    Institute of Scientific and Technical Information of China (English)

    王道庚

    2007-01-01

    @@ letter作"信"讲是很常用的词,私人信件是personal letter,业务信件叫做business letter,祝贺信是letter of congratulation,邀请信是letter of invitation 等等.还有一种信是a bread-and-butter letter,你知道是什么信吗?我们知道bread and butter是涂有黄油的面包,那么,a bread-and-butter letter就是"黄油面包信"吧?非也.

  19. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Veggie Dream I was interested to read your articles about vegetarianism(January issue) and how it is catching on in China.I always imagined China to be a meat eating country before. Being vegetarian is very misunderstood by many people.I am a vegetarian and it has taught me to be very tolerant.If I go to any banquet,dinner,buffet,cocktail party,or any other event where food is served,I have learned to always try and eat beforehand or at least carry some of my own snacks.Vegetarians are rarely,if ever,catered for at social events,apart from the odd carrot or celery stick,tucked away in between the moun-

  20. Letters

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    My name is Tom R. Chambers. I have been teaching English in Sheng Da College (near Zhengzhou) for two years,and faithfully reading your publication for over a year. I am also a documentary photographer, and I wonder if you'd be interested in publishing my experiences in China. I've created a Sheng Da College/China Travels website, which I feel is aninteresting approach to a travelogue,

  1. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Give Peace a Chance The African Union(AU) has put forward a four-point formula to end the civil war in Libya.These points are:an immediate ceasefire by all military actions;continued humanitarian aid to those in need;protection of foreigners,including African expatriates living in Libya;and creation of a necessary political reforms agenda to eliminate the causes of the present crisis.This is all a clear indication that the AU is

  2. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Female Farmers Zambian female farming groups are very happy to hear the news that the government has launched a $500,000 Sustainable Livelihood and Women Empowerment Project. Poor women farmer groups will now at least have some opportunity of getting financial help as well as help with new technology.We women farmers will also get help with training and livestock resources.The project is said to support 1,900 households and is in part of the process toward meeting the millennium goals.

  3. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Despicable Acts Images of children starving to death are always disturbing.After reading a report about how food aid is being stolen and then sold on the market in Somalia I was saddened,sickened and outraged at the same time.A news report from Associated Press said that the food reaches the hungry people in the refugee camps and is then being removed from them with threats of violence and sold for profit.What kind of people are these that we share the planet with.What would make someone

  4. LETTERS

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    Dear Editor, Ref.To our tele talk to day,I have the honour to write you as you claimed that"Rarely do journalist challenge the Dalai Lama". Dalai Lama is an hypocrite who used to systematically fool people and his principle of peace are too bogus,he must be stopped in the frame work of peace as his fol-lowers are sluggish and kept themself burried under ignorance.

  5. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    EkooniBaje It brings me much joy to write about your article on Lagos(February issue).I felt obliged to use this opportunity to show to China and the rest of the world that there is a home for them in Lagos."Eko o ni Baje" is a popular local slogan in Lagos,Nigeria which simply means "Lagos will not spoil." Recently,the Nigerian community in Beijing and across China together with the Chinese Government celebrated 40 years of bilateral trade relations with China.This is to

  6. Letters

    Science.gov (United States)

    2000-04-01

    Coulombic Models in Chemical Bonding by Lawrence J. Sacks and by Derek W. Smith Re: articles by R. J. Gillespie and by D. W. Smith D. W. Smith replies Capsaicin Hazard by Paul E. Vorndam Re: article by J. D. Batchelor and B. T. Jones B. T. Jones reply Editor's Note: Hazards Re: JCE 1999, 76, 240 and JCE 2000, 77, 266.

  7. LETTERS

    Institute of Scientific and Technical Information of China (English)

    2006-01-01

    Tobacco Problem Your recent cover story 'Tobacco Dilemma" (Issue No.9, March 2, 2006) should not be a dilemma at all. The Chinese Government should just come down very hard on cigarette smoking. It does not make sense to let tobacco smoking proliferate because it enriches government coffers through heftv taxes. Tobacco smokine is an

  8. Letters

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    Waste Not,Want Not I enjoy reading your magazine and was moved by your story about the massive famine in the Horn of Africa in your September issue.Last week I attended a banquet for an outgoing official at a popular restaurant in Beijing.We had many different dishes and after we had finished I noticed how much food remained uneaten on the table.After having read your story I thought about how so much is wasted in one place and so much needed in another.How does that happen? I felt guilty and wanted to do something to help at that moment. I think as people sharing the same planet we must be aware of what goes on

  9. LETTERS

    Institute of Scientific and Technical Information of China (English)

    Deqyi

    2008-01-01

    Dear degyi, Number two arrived-it looks good-it looks normal Tibet again after all that NEWS NEWS NEWS we had last week about Lhasa.I haven't read it yet-just turning the pages to get first impression. I like the clear printing pictures of mountains Tibetan areas,Tibetan horse,Tibetan sheep grazing at foot of mountains,Tibetan girls in out of this world Tibetan dresses,Tibetan town under Heaven, Kyirong men,rope bridge with streamers.Tibetan history engraved in rock; I like beer-but I don't like beer tac...

  10. Pragmatic Functions of Hedges in Business Letters

    Institute of Scientific and Technical Information of China (English)

    刘璐璐

    2013-01-01

    The aim of the present research to explore the hedges used English business letters. Several samples have been chosen to make qualitative study in order to achieve the goal of answering the following question: what are the pragmatic functions of hedges being used in business letters? After analyzing the samples, the conclusion could be came that the employment of hedges in business letters has three pragmatic functions—giving the right amount of information, being polite and self-production.

  11. Secret letters cast light on Copenhagen

    Energy Technology Data Exchange (ETDEWEB)

    Durrani, Matin

    2001-11-01

    Letters by Niels Bohr that have been kept secret since his death could explain the mystery of why Werner Heisenberg visited him in Copenhagen in 1941. When the author Michael Frayn spent two years writing Copenhagen, he had no idea how successful the play would become. He doubted that audiences would sit through a historical drama about a war-time meeting between Werner Heisenberg - head of Germany's nuclear programme - and his old mentor Niels Bohr in the Nazi-occupied Danish capital in 1941. But Frayn's efforts paid off. Audiences and critics alike have thrilled at the way the award-winning play probes the historical uncertainty that surrounds the encounter. Was Heisenberg fishing for information about the Allies' atomic plans - or was he trying to recruit Bohr for Germany's bomb programme? Did Heisenberg want to suggest that the Germans were close to finishing a bomb so that the Allies would make peace with Hitler? Maybe he was simply seeking approval from Bohr for his own atomic work. There is also a moral debate: did Heisenberg know how to build a bomb, but decided not to - or did he want to build one, but got his calculations wrong? Unfortunately, no-one was there to record or observe the encounter and we cannot know for sure what was said or implied between the two men. All we do know is that the pair dined together and took a short walk - and that the incident damaged Bohr and Heisenberg's friendship forever. To piece together what happened, historians of science have had to rely on Heisenberg's post-war recollections - which have been ambiguous and contradictory - along with scraps of evidence from secondary sources. (U.K.)

  12. Resource Letter: GW-1: Global warming

    Science.gov (United States)

    Firor, John W.

    1994-06-01

    This Resource Letter provides a guide to the literature on the possibility of a human-induced climate change—a global warming. Journal articles and books are cited for the following topics: the Greenhouse Effect, sources of infrared-trapping gases, climate models and their uncertainties, verification of climate models, past climate changes, and economics, ethics, and politics of policy responses to climate change. [The letter E after an item indicates elementary level or material of general interest to persons becoming informed in the field. The letter I, for intermediate level, indicates material of somewhat more specialized nature, and the letter A indicates rather specialized or advanced material.

  13. Effect of orthographic processes on letter-identity and letter-position encoding in dyslexic children

    Directory of Open Access Journals (Sweden)

    Caroline eReilhac

    2012-05-01

    Full Text Available The ability to identify letters and encode their position is a crucial step of the word recognition process. However and despite their word identification problem, the ability of dyslexic children to encode letter-identity and letter-position within strings was not systematically investigated. This study aimed at filling this gap and further explored how letter identity and letter position encoding is modulated by letter context in developmental dyslexia. For this purpose, a letter-string comparison task was administered to French dyslexic children and two chronological-age (CA and reading-age (RA-matched control groups. Children had to judge whether two successively and briefly presented 4-letter-strings were identical or different. Letter-position and letter-identity were manipulated through the transposition (e.g., RTGM vs. RMGT or substitution of two letters (e.g., TSHF vs. TGHD. Non-words, pseudo-words and words were used as stimuli to investigate sub-lexical and lexical effects on letter encoding. Dyslexic children showed both substitution and transposition detection problems relative to CA controls. A substitution advantage over transpositions was only found for words in dyslexic children whereas it extended to pseudo-words in RA controls and to all type of items in CA controls. Letters were better identified in the dyslexic group when belonging to orthographically familiar strings. Letter position encoding was very impaired in dyslexic children who did not show any word context effect in contrast to CA controls. Overall, the current findings point to a strong letter identity and letter position encoding disorder in developmental dyslexia.

  14. Letters from the Future: Suggestions for Using Letter Writing as a School Counselling Intervention

    Science.gov (United States)

    Kress, Victoria E.; Hinkle, Michelle Gimenez; Protivnak, Jake J.

    2011-01-01

    This article presents a school counselling intervention that utilises letters written from the future. Few peer-reviewed articles have addressed the use of letter writing in a school counselling context, and none have focused on the use of letters from the future as a means of school counsellor intervention. The authors present a theoretical…

  15. Disentangling the Developmental Trajectories of Letter Position and Letter Identity Coding Using Masked Priming

    Science.gov (United States)

    Kezilas, Yvette; McKague, Meredith; Kohnen, Saskia; Badcock, Nicholas A.; Castles, Anne

    2017-01-01

    Masked transposed-letter (TL) priming effects have been used to index letter position processing over the course of reading development. Whereas some studies have reported an increase in TL priming over development, others have reported a decrease. These findings have led to the development of 2 somewhat contradictory accounts of letter position…

  16. Prefix Codes: Equiprobable Words, Unequal Letter Costs

    OpenAIRE

    Golin, Mordecai; Young, Neal E.

    2002-01-01

    Describes a near-linear-time algorithm for a variant of Huffman coding, in which the letters may have non-uniform lengths (as in Morse code), but with the restriction that each word to be encoded has equal probability. [See also ``Huffman Coding with Unequal Letter Costs'' (2002).

  17. Genre Analysis of Letters of Complaint

    Institute of Scientific and Technical Information of China (English)

    曹劲草

    2014-01-01

    This article makes a genre analysis of letter of complaint according to Swales’ theory in hope that some enlightenment wil be provided for the traders in writing letters of complaint in a more efficient way. The study focus on the structural features, grammatical features and lexical features.

  18. Feminist Criticism in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    魏福林; 何志燕

    2007-01-01

    The Scarlet Letter written by Nathaniel Hawthorne is a great book. Through feminist criticism we can get how The Scarlet Letter may be read as dramatizing Hester Prynne's spiritual and physical struggle to survive as an individual in a society whose values authorize the privileged power of men.

  19. Reflection on Letter from Birmingham Jail

    Institute of Scientific and Technical Information of China (English)

    张远艳; 罗瑞

    2015-01-01

    "Letter from Birmingham Jail" is written by Martin Luther King,Jr.,who is a famous American civil rights leader.This essay attempts to analyze three major arguments in this letter to arouse people’s consciousness to cherish and protect our freedom.

  20. Reflection on Letter from Birmingham Jail

    Institute of Scientific and Technical Information of China (English)

    张远艳; 罗瑞

    2015-01-01

    Letter from Birmingham Jail” is written by Martin Luther King,Jr.,who is a famous American civil rights leader.This essay attempts to analyze three major arguments in this letter to arouse people’s consciousness to cherish and protect our freedom.

  1. Essay: the origin of physical review letters.

    Science.gov (United States)

    Trigg, George L

    2008-11-21

    When Sam Goudsmit, then Editor of Physical Review, decided to publish the Letters separately, he asked me to become Assistant Editor of the new journal. I wound up staying at PRL for a quarter of a century. I describe some of the new techniques we developed to speed up review and production so that Letters could be quickly published.

  2. Design Improvements for Frequently Misrecognized Letters

    DEFF Research Database (Denmark)

    Beier, Sofie; Larson, Kevin

    2010-01-01

    To enhance typeface legibility we studied how to improve the design of individual letters. Three diff erent fonts were created, each containing several variations of the most frequently misrecognized letters. These variations were tested both with distance and short exposure methodologies. Creati...

  3. TEACHERS' VIEWS ON CURSIVE LETTERS FONTS

    Directory of Open Access Journals (Sweden)

    Erol DURAN

    2011-06-01

    Full Text Available This study is subject to forms of writing letters in cursive font. Research is descriptive screening model. Researcher, 227 primary school teachers with the first writing in cursive writing teaching to previously made in the province and district in Ankara, " Cursive Letters Shape Writing Assessment" named semi-structure interview form applied. Teachers in this survey, the shape of the letter, if appropriate, the letter an "appropriate" to write, did not find the appropriate letter in the shape of the new propositions were asked to spell. The data was descriptively analysed and interpreted after then. 16% of teachers participating in the research, the teaching of cursive writing not find a significant and steep wants to return to perpendicular to the basic text writing. 12% of the teachers, the cursive letters stated that the whole appropriate shape patterns grows. Participated in the study with other teachers, most of the letters in "appropriate" expression while falling, "b, d, f, k, r, s, ş, v, z, B, D, L, T, Z" the letters and shape patterns indicate that it should be changed new faces in this case suggested shape.

  4. Writing Back and Forth: Class Letters.

    Science.gov (United States)

    Fulwiler, Toby

    1997-01-01

    Recommends that college teachers and their students exchange weekly letters, in either paper or electronic form, as a familiar and friendly means of communication. The method increases dialog, suggests rethinking, and encourages rewriting while keeping the stakes low. Students respond well to the assignment. Samples of student letters and comments…

  5. 24 CFR 241.1010 - Feasibility letter.

    Science.gov (United States)

    2010-04-01

    ... 24 Housing and Urban Development 2 2010-04-01 2010-04-01 false Feasibility letter. 241.1010 Section 241.1010 Housing and Urban Development Regulations Relating to Housing and Urban Development...-Eligibility Requirements § 241.1010 Feasibility letter. (a) Request for study. The owner may request...

  6. From Numbers to Letters: Feedback Regularization in Visual Word Recognition

    Science.gov (United States)

    Molinaro, Nicola; Dunabeitia, Jon Andoni; Marin-Gutierrez, Alejandro; Carreiras, Manuel

    2010-01-01

    Word reading in alphabetic languages involves letter identification, independently of the format in which these letters are written. This process of letter "regularization" is sensitive to word context, leading to the recognition of a word even when numbers that resemble letters are inserted among other real letters (e.g., M4TERI4L). The present…

  7. Letter identification and the neural image classifier.

    Science.gov (United States)

    Watson, Andrew B; Ahumada, Albert J

    2015-02-12

    Letter identification is an important visual task for both practical and theoretical reasons. To extend and test existing models, we have reviewed published data for contrast sensitivity for letter identification as a function of size and have also collected new data. Contrast sensitivity increases rapidly from the acuity limit but slows and asymptotes at a symbol size of about 1 degree. We recast these data in terms of contrast difference energy: the average of the squared distances between the letter images and the average letter image. In terms of sensitivity to contrast difference energy, and thus visual efficiency, there is a peak around ¼ degree, followed by a marked decline at larger sizes. These results are explained by a Neural Image Classifier model that includes optical filtering and retinal neural filtering, sampling, and noise, followed by an optimal classifier. As letters are enlarged, sensitivity declines because of the increasing size and spacing of the midget retinal ganglion cell receptive fields in the periphery.

  8. [Lake Mason and Soo Line Marsh project design approval

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This letter is the approval from the U.S. Fish and Wildlife Service of the designs created by Ducks Unlimited, Inc. for the Lake Mason and Soo Line Marsh National...

  9. Drugs Approved for Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for ovarian cancer. The list includes generic names, brand names, and common drug combinations, which are shown in capital letters. The drug names link to NCI's Cancer Drug Information summaries.

  10. Critical contrastive rhetoric: The influence of L2 letter writing instruction on L1letter writing

    Directory of Open Access Journals (Sweden)

    Mehrnoosh Fakharzadeh

    2014-08-01

    Full Text Available The present study employed critical contrastive rhetoric to investigate the L2 to L1 transfer of organizational pattern and directness level of speech acts in business complaint letters. By examining the L1 complaint letters of 30 tourism university students in two phases of study, pre and post instruction of English complaint letter, the study revealed that the rhetorical organization of Persian letters are in a state of hybridity. The post instruction comparison of letters, however, showed a tendency towards applying English conventions both in organization and directness level of complaint speech act in the L1 complaint letters. The results also revealed that after instruction the expert in the field of tourism viewed some letters as inappropriate in terms of politeness which is reflected through some lexical items.

  11. Differences between English and Chinese Sales Promotion Letters

    Institute of Scientific and Technical Information of China (English)

    PANG Yu-yan

    2015-01-01

    This paper aims to figure out the differences in English and Chinese sales promotion letters by analyzing ten selected letters from business writing books and websites, which might provide more valuable information for businessmen in their sales promotion letter writing.

  12. Statistical mechanics of letters in words.

    Science.gov (United States)

    Stephens, Greg J; Bialek, William

    2010-06-01

    We consider words as a network of interacting letters, and approximate the probability distribution of states taken on by this network. Despite the intuition that the rules of English spelling are highly combinatorial and arbitrary, we find that maximum entropy models consistent with pairwise correlations among letters provide a surprisingly good approximation to the full statistics of words, capturing ∼92% of the multi-information in four-letter words and even "discovering" words that were not represented in the data. These maximum entropy models incorporate letter interactions through a set of pairwise potentials and thus define an energy landscape on the space of possible words. Guided by the large letter redundancy we seek a lower-dimensional encoding of the letter distribution and show that distinctions between local minima in the landscape account for ∼68% of the four-letter entropy. We suggest that these states provide an effective vocabulary which is matched to the frequency of word use and much smaller than the full lexicon.

  13. A letter from Janet Benshoof.

    Science.gov (United States)

    Benshoof, J

    1997-06-06

    This letter to readers of "Reproductive Freedom News" criticizes the American Medical Association's (AMA) Board of Trustees for endorsing a bill in the US Senate that would ban "partial-birth" abortions and allow the imprisonment of physicians who perform the procedure. The decision of the Board of Trustees was made in total disregard to the AMA bylaws, because the decision ran counter to the recommendations of an AMA task force that concluded that the AMA should take no action on this bill but seek to preserve the ability of physicians to use their discretion in providing medical care and the viability line in abortion legislation. The proposed criminal ban fails to contain a viability line; provides no exception to protect a woman's health, medical choice, or safety; and provides no exception in cases of fetal anomaly. The action by the Board of Trustees seriously undermines the work of the Center for Reproductive Law and Policy and gives abortion opponents ammunition to mount a serious challenge to the Roe vs. Wade decision. The AMA endorsement goes beyond simply stating that the procedure should never be used; it endorses giving physicians who perform such abortions, for whatever reason, prison terms. This position undermines two critical principles long upheld by the AMA: 1) that physicians must be able to carry out their medical responsibilities free from government interference and 2) that women have a fundamental right to decide on the appropriate provision of abortion services within their physician-patient relationship. The damage from this endorsement can and should be undone by the AMA's House of Delegates at their meeting in June 1997.

  14. Gender bias found in recommendation letters

    Science.gov (United States)

    Kruesi, Liz

    2016-11-01

    Female postdoctoral fellowship applicants are half as likely as their male counterparts to receive glowing recommendation letters, according to a study by researchers at Columbia University's Lamont-Doherty Earth Observatory (LDEO).

  15. Letter to President [Valentine National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Secretary of the Interior to the President regarding the establishment of the Valentine National Wildlife Refuge Wilderness area....

  16. Stochastic Flips on Two-letter Words

    CERN Document Server

    Bodini, Olivier; Regnault, Damien

    2010-01-01

    This paper introduces a simple Markov process inspired by the problem of quasicrystal growth. It acts over two-letter words by randomly performing \\emph{flips}, a local transformation which exchanges two consecutive different letters. More precisely, only the flips which do not increase the number of pairs of consecutive identical letters are allowed. Fixed-points of such a process thus perfectly alternate different letters. We show that the expected number of flips to converge towards a fixed-point is bounded by $O(n^3)$ in the worst-case and by $O(n^{5/2}\\ln{n})$ in the average-case, where $n$ denotes the length of the initial word.

  17. 2013 FEMA Letter of Map Revision

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  18. Scott's Lake Excavation Letters on Human Remains

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This is two letters written about the repatriation of Santee Indian human remains and funerary objects to Santee Sioux Tribe. Includes an inventory of human remains...

  19. Drugs Approved for Melanoma

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Melanoma This page lists cancer drugs approved by the ... that are not listed here. Drugs Approved for Melanoma Aldesleukin Cobimetinib Cotellic (Cobimetinib) Dabrafenib Dacarbazine DTIC-Dome ( ...

  20. Symbols of Pearl in The Scarlet letter

    Institute of Scientific and Technical Information of China (English)

    Li Aiqing

    2002-01-01

    This article evaluates The Scatet Letter with the help of analyzing the symbolic meanings of Pearl. In this article, the author attempts to propose the symbols of Pearl from four aspects: the function of the letter, the symbol of Hester's distillation of instinct;the symbol of freedom; the symbol of consummation. From the interpretation of the symbols of Pearl, it has been proved that Pearl becomes Hawthorne' s best vehicle to convey his attitudes toward Puritanism.

  1. On the Commercial Features of Business Letters

    Institute of Scientific and Technical Information of China (English)

    邬娜

    2008-01-01

    Effective business communication is the"lifeblood"of every organization and a key to success in your business career. Generally,each trade or each business achieves an agreement and then draws up a contract after buyer and seller exchange business letter. Thus,a successful business letter is one of the most personal method to promote a business career. The paper informs how to write suc-cessful correspondence.

  2. On Coding Non-Contiguous Letter Combinations

    Directory of Open Access Journals (Sweden)

    Frédéric eDandurand

    2011-06-01

    Full Text Available Starting from the hypothesis that printed word identification initially involves the parallel mapping of visual features onto location-specific letter identities, we analyze the type of information that would be involved in optimally mapping this location-specific orthographic code onto a location-invariant lexical code. We assume that some intermediate level of coding exists between individual letters and whole words, and that this involves the representation of letter combinations. We then investigate the nature of this intermediate level of coding given the constraints of optimality. This intermediate level of coding is expected to compress data while retaining as much information as possible about word identity. Information conveyed by letters is a function of how much they constrain word identity and how visible they are. Optimization of this coding is a combination of minimizing resources (using the most compact representations and maximizing information. We show that in a large proportion of cases, non-contiguous letter sequences contain more information than contiguous sequences, while at the same time requiring less precise coding. Moreover, we found that the best predictor of human performance in orthographic priming experiments was within-word ranking of conditional probabilities, rather than average conditional probabilities. We conclude that from an optimality perspective, readers learn to select certain contiguous and non-contiguous letter combinations as information that provides the best cue to word identity.

  3. Letter Position Dyslexia in Arabic: From Form to Position

    Science.gov (United States)

    Friedmann, Naama; Haddad-Hanna, Manar

    2012-01-01

    This study reports the reading of 11 Arabic-speaking individuals with letter position dyslexia (LPD), and the effect of letter form on their reading errors. LPD is a peripheral dyslexia caused by a selective deficit to letter position encoding in the orthographic-visual analyzer, which results in migration of letters within words, primarily of middle letters. The Arabic orthography is especially interesting for the study of LPD because Arabic letters have different forms in different positions in the word. As a result, some letter position errors require letter form change. We compared the rate of letter migrations that change letter form with migrations that do not change letter form in 10 Arabic-speaking individuals with developmental LPD, and one bilingual Arabic and Hebrew-speaking individual with acquired LPD. The results indicated that the participants made 40% letter position errors in migratable words when the resulting word included the letters in the same form, whereas migrations that changed letter form almost never occurred. The error rate of the Arabic-Hebrew bilingual reader was smaller in Arabic than in Hebrew. However, when only words in which migrations do not change letter form were counted, the rate was similar in Arabic and Hebrew. Hence, whereas orthographies with multiple letter forms for each letter might seem more difficult in some respects, these orthographies are in fact easier to read in some forms of dyslexia. Thus, the diagnosis of LPD in Arabic should consider the effect of letter forms on migration errors, and use only migratable words that do not require letter-form change. The theoretical implications for the reading model are that letter form (of the position-dependent type found in Arabic) is part of the information encoded in the abstract letter identity, and thus affects further word recognition processes, and that there might be a pre-lexical graphemic buffer in which the checking of orthographic well-formedness takes place

  4. Neural Correlates of Top-Down Letter Processing

    Science.gov (United States)

    Liu, Jiangang; Li, Jun; Zhang, Hongchuan; Rieth, Cory A.; Huber, David E.; Li, Wu; Lee, Kang; Tian, Jie

    2010-01-01

    This fMRI study investigated top-down letter processing with an illusory letter detection task. Participants responded whether one of a number of different possible letters was present in a very noisy image. After initial training that became increasingly difficult, they continued to detect letters even though the images consisted of pure noise,…

  5. 33 CFR 127.009 - Letter of recommendation.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Letter of recommendation. 127.009... General § 127.009 Letter of recommendation. After the COTP receives the Letter of Intent under § 127.007(a) or (b), the COTP issues a Letter of Recommendation as to the suitability of the waterway for LNG...

  6. Representation of Letter Position in Spelling: Evidence from Acquired Dysgraphia

    Science.gov (United States)

    Fischer-Baum, Simon; McCloskey, Michael; Rapp, Brenda

    2010-01-01

    The graphemic representations that underlie spelling performance must encode not only the identities of the letters in a word, but also the positions of the letters. This study investigates how letter position information is represented. We present evidence from two dysgraphic individuals, CM and LSS, who perseverate letters when spelling: that…

  7. Letter-Transposition Effects Are Not Universal: The Impact of Transposing Letters in Hebrew

    Science.gov (United States)

    Velan, Hadas; Frost, Ram

    2009-01-01

    We examined the effects of letter-transposition in Hebrew in three masked-priming experiments. Hebrew, like English has an alphabetic orthography where sequential and contiguous letter strings represent phonemes. However, being a Semitic language it has a non-concatenated morphology that is based on root derivations. Experiment 1 showed that…

  8. Alphabetic skills in preschool: a preliminary study of letter naming and letter writing.

    Science.gov (United States)

    Molfese, Victoria J; Beswick, Jennifer; Molnar, Andrew; Jacobi-Vessels, Jill

    2006-01-01

    Development of letter naming and writing (skills in writing first name, dictated and copied letters, and dictated and copied numbers) was examined in 79 preschool children (M age = 56 months). Skills were assessed in the fall to determine the status of these procedural skills that are components of alphabetic knowledge at the start of the school year. Children with high letter-naming scores also had high scores on letter writing, including dictated or copied letters and writing some or all of the letters of their names. Letter-naming skills were related to number-writing skills whether the numbers were dictated or copied. The highest writing scores were found for first name writing compared to writing or copying letters and numbers. A focus on the development of procedural knowledge in the preschool period may yield the hopep for impacts on later reading skills that has not been found in curricula emphasizing conceptual knowledge (e.g., knowledge of print concepts, book conventions).

  9. ERP Correlates of Letter Identity and Letter Position Are Modulated by Lexical Frequency

    Science.gov (United States)

    Vergara-Martinez, Marta; Perea, Manuel; Gomez, Pablo; Swaab, Tamara Y.

    2013-01-01

    The encoding of letter position is a key aspect in all recently proposed models of visual-word recognition. We analyzed the impact of lexical frequency on letter position assignment by examining the temporal dynamics of lexical activation induced by pseudowords extracted from words of different frequencies. For each word (e.g., BRIDGE), we created…

  10. The Symbolic Significance of The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    张力

    2007-01-01

    As a great romantic novelist in America in 19th century, Hawthorne was outstanding in handling the application of symbolism. The Scarlet Letter is Hawthorne's most important symbolic novel, which stands as the best work of Hawthorne and one of the indubitable masterpieces of American literature. This thesis aims at the exploration of the usage of the symbolism in the novel. It mainly discusses the deep symbolic significance of the scarlet letter "A" and the little pearl. The scarlet letter is the central symbol of the novel. Its symbolic meaning changes from 'adultery' to 'able', even 'angelic' in the novel. It also examines the symbolic meanings of little Pearl and some typical natural surroundings such as the jail, the forest, the rosebush and so on.

  11. A bread-and-butter letter

    Institute of Scientific and Technical Information of China (English)

    王道庚

    2007-01-01

    letter作“信”讲是很常用的词,私人信件是personal letter。业务信件叫做business letter,祝贺信是letter of congratulation,邀请信是letter of invitation等等。还有一种信是a bread—and—butter letter,你知道是什么信吗?我们知道bread and butter是涂有黄油的面包,那么,a bread—and—butter leuer就是“黄油面包信”吧?非也。

  12. Traditions of martyrdom in the Ignatian Letters

    Directory of Open Access Journals (Sweden)

    S. Fuhrmann

    2011-06-01

    Full Text Available The letters of Ignatius represent one of the key texts for the emergence of martyrdom during the second century AD in Christianity. This article is concerned with the question whether Ignatius contributed to a “theology of martyrdom” or whether he rather relied on previous traditions. The author argues, by undertaking an analysis of certain pragmatics and semantics, that the motif of martyrdom is solely used to buttress Ignatius’ claim for authority among his intended addressees by referring to an understanding of martyrdom that has its roots in the New Testament. An identification of the author of the letters with a historical martyr is regarded as unlikely.

  13. [Structured electronic consultation letter for shoulder disorders].

    Science.gov (United States)

    Paloneva, Juha; Oikari, Marjo; Ylinen, Jari; Ingalsuo, Minna; Ilkka, Kunnamo; Ilkka, Kiviranta

    2012-01-01

    Referral to a specialist has a significant influence on management of the patient and costs associated with the treatments. However, development and research of the process by which patients are referred has been almost neglected. Expectations considering the purpose, contents, and timing of the referral of the consulting physician and the consultant do not always meet. A structured, electronic consultation letter was developed to respond this need. Functionality and interactivity are the key elements of the referral, including (1) an electronic referral letter to a specialist, (2) interactive education in clinical examination and management of shoulder disorders, and (3) an instrument of clinical examination and documentation of shoulder disorders.

  14. Letters in the Forest: Global precedence effect disappears for letters but not for non-letters under reading-like conditions

    Directory of Open Access Journals (Sweden)

    Thomas eLachmann

    2014-07-01

    Full Text Available Normally-skilled reading involves special processing strategies for letters, which are habitually funneled into an abstract letter code. On the basis of previous studies we argue that this habit leads to the preferred usage of an analytic strategy for the processing of letters, while non-letters are preferably processed via a holistic strategy. The well-known Global Precedence Effect (GPE seems to contradict to this assumption, since, with compound, hierarchical figures, including letter items, faster responses are observed to the global than to the local level of the figure, as well as an asymmetric interference effect from global to local level. We argue that with letters these effects depend on presentation conditions; only when they elicit the processing strategies automatized for reading, an analytic strategy for letters in contrast to non-letters is to be expected. We compared the GPE for letters and non-letters in central viewing, with the global stimulus size close to the functional visual field in whole word reading (6.5o of visual angle and local stimuli close to the critical size for fluent reading of individual letters (.5o of visual angle. Under these conditions, the GPE remained robust for non-letters. For letters, however, it disappeared: letters showed no overall response time advantage for the global level and symmetric congruence effects (local-to-global as well as global-to local interference. We interpret these results as according to the view that reading is based on resident analytic visual processing strategies for letters.

  15. Reply to letter to the editor

    NARCIS (Netherlands)

    Woelders, H.

    2006-01-01

    In response to the letter by Dr. Amir Arav I would like to mention the following. The application of the principle of directional solidification to cryopreservation of living cells was, as far as I am aware, not the invention of Dr. Arav. It was first published and patented by Rubinsky (Berkeley, CA

  16. Crowding Affects Letters and Symbols Differently

    Science.gov (United States)

    Grainger, Jonathan; Tydgat, Ilse; Issele, Joanna

    2010-01-01

    Five experiments examined crowding effects with letter and symbol stimuli. Experiments 1 through 3 compared 2-alternative forced-choice (2AFC) identification accuracy for isolated targets presented left and right of fixation with targets flanked either by 2 other items of the same category or a single item situated to the right or left of targets.…

  17. Application of Politeness Strategies in Business Letters

    Institute of Scientific and Technical Information of China (English)

    杨雅婷

    2015-01-01

    As is known to all,businesses are very image - conscious. Most of the companies try to conduct themselves decently and politely in their business transactions,among which business letters are major manifestations of politeness. Application of Politeness Strategies is of great significance.

  18. Varsity letters documenting modern colleges and universities

    CERN Document Server

    Samuels, Helen Willa

    1998-01-01

    A study of the functions of colleges and universities, Varsity Letters is intended to aid those responsible for the documentation of these institutions. Samuels offers specific advice about the records of modern colleges and universities and proposes a method to ensure their adequate documentation. She also offers a method to analyze and plan the preservation of records for any type of institution.

  19. Fallout from Chernobyl [Letters to the editor

    Energy Technology Data Exchange (ETDEWEB)

    Williams, E.D. (Addenbrooke' s Hospital, Cambridge (United Kingdom)); Abelin, T.; Egger, M. (Bern Univ. (Switzerland)) (and others)

    1994-11-12

    Six brief letters discuss the possible health effects of fallout from the Chernobyl reactor accident including an increase in thyroid cancer in children in Belarus, chromosomal abnormalities in workers from Latvia who cleared up the Chernobyl accident site, an increased trisomy 21 in Berlin but a lack of increased childhood leukaemia incidence in Greece. (UK).

  20. Letter of the Editor-in-chief

    Institute of Scientific and Technical Information of China (English)

    Shiwen Wang; Mathew Sorrentino; Thach Nguyen

    2006-01-01

    @@ Dear Friends and Colleagues, In this letter, I would like to celebrate the second anniversary of the Journal of Geriatric Cardiology (JGC).With the help of all of you, friends and colleagues, readers,editorials consultants, authors and editorial staff, the JGC was able to grow and publish many quality papers from the world.

  1. Samuel Beckett: Color, Letter, and Line.

    Science.gov (United States)

    Conley, Tom

    1985-01-01

    Through a bilingual reading of Beckett's "Mal vu mal dit," the illusion of painted relief for printed letters is created. Colors manifest themselves through the continual process of translation. The French translation adds color to the black and white English text. (DF)

  2. Researches Made on The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    王舫

    2011-01-01

    Being the first American native novel,a great number of researches have been made on The Scarlet Letter.This paper collects some popular researches that have been made on this novel and classifies them into five perspectives --- romance,symbolism,Puritanism,feminism and psychoanalysis.

  3. The Electronic Discharge Letter Mobile App

    NARCIS (Netherlands)

    Lezcano, Leonardo; Ternier, Stefaan; Drachsler, Hendrik; Kalz, Marco; Specht, Marcus

    2013-01-01

    Lezcano, L., Ternier, S., Drachsler, H., Kalz, M., & Specht, M. (2013, September). The Electronic Discharge Letter Mobile App. In iProceedings of MEDICINE 2.0: 6th World Congress on Social Media, Mobile Apps, Internet/Web 2.0 (pp. 221-222). London, England. Retrieved from http://www.medicine20congre

  4. Readerly and Writerly "Letters from the Park."

    Science.gov (United States)

    Conde, Susana

    1993-01-01

    Discusses in depth the film "Cartas del parque" ("Letters from the Park"), the first of six films in the "Amores Dificiles" series. Notes that the film is pervaded by the traditional overdetermination of gender roles. Suggests that an intrusive and authoritative narrator makes of this both a "readerly" and a…

  5. 42 CFR 93.202 - Charge letter.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Charge letter. 93.202 Section 93.202 Public Health PUBLIC HEALTH SERVICE, DEPARTMENT OF HEALTH AND HUMAN SERVICES HEALTH ASSESSMENTS AND HEALTH EFFECTS STUDIES OF HAZARDOUS SUBSTANCES RELEASES AND FACILITIES PUBLIC HEALTH SERVICE POLICIES ON...

  6. An Unknown Letter by Maria Komornicka

    Directory of Open Access Journals (Sweden)

    Mateusz Bourkane

    2013-01-01

    Full Text Available The study presents an unpublished letter by Maria Komornicka, which the poet sent in July 1899 to her aunt, Aleksandra Oszacka. The epistolary communication, which contains several pieces of information about the life and activities of the poet living in Warsaw, can be a valuable material for researchers interested in her biography.

  7. Hester Prynne in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    赵丽

    2011-01-01

    The Scarlet Letter is the masterpiece of Nathaniel Hawthorne, one of the great writers in the nineteenth century America. Since it was published in the year of 1850, it has been reread in the circle of literary criticism..In the book, Hawthorne Portrays H

  8. SiD Letter of Intent

    CERN Document Server

    Aihara, H; Oreglia, M.; Berger, E.L.; Guarino, V.; Repond, J.; Weerts, H.; Xia, L.; Zhang, J.; Zhang, Q.; Srivastava, A.; Butler, J.M.; Goldstein, Joel; Velthuis, J.; Radeka, V.; Zhu, R.-Y.; Lutz, P.; de Roeck, A.; Elsener, K.; Gaddi, A.; Gerwig, H.; Grefe, C.; Klempt, W.; Linssen, L.; Schlatter, D.; Speckmayer, P.; Thom, J.; Yang, J.; Christian, D.C.; Cihangir, S.; Cooper, W.E.; Demarteau, M.; Fisk, H.E.; Garren, L.A.; Krempetz, K.; Kutschke, R.K.; Lipton, R.; Para, A.; Tschirhart, R.; Wenzel, H.; Yarema, R.; Grunewald, M.; Pankov, A.; U., Gomel State Tech.; Dutta, T.; Dauncey, P.D.; Balbuena, J.P.; Fleta, C.; Lozano, M.; Ullan, M.; Christian, G.B.; Faus-Golfe, A.; Fuster, J.; Lacasta, C.; Marinnas, C.; Vos, M.; Duarte, J.; Fernandez, M.; Gonzalez, J.; Jaramillo, R.; Lopez, Virto, A.; Martinez-Eivero, C.; Moya, D.; Ruiz-Mimeno, A.; Vila, I.; Colledani, C.; Dorokhov, A.; Hu-Guo, C.; Winter, M.; Moortgat-Pick, G.; Onoprienko, D.V.; Kim, G.N.; Park, H.; Adloff, C.; Blaha, J.; Blaising, J.-J.; Cap, S.; Chefdeville, M.; Drancourt, C.; Espargiliare, A.; Gaglione, R.; Geffroy, N.; Jacquemier, J.; Karyotakis, Y.; Prast, J.; Vouters, G.; Gronberg, J.; Walston, S.; Wright, D.; Sawyer, L.; Laloum, M.; Ciobanu, C.; Chauveau, J.; Savoy-Navarro, A.; Andricek, L.; Moser, H.-G.; Cowan, R.f.; Fisher, P.; Yamamoto, R.K.; Kenney, ClMl; Boos, E.E.; Merkin, M.; Chen, S.; Chakraborty, D.; Dyshkant, A.; Hedin, D.; Zutshi, V.; Galkin, V.; D'Ascenzo, N.; Ossetski, D.; Saveliev, V.; Kapusta, F.; De Masi, R.; Vrba, V.; Lu, C.; McDonald, K.T.; Smith, A.J.S.; Bortoletto, D.; Coath, R.; Crooks, J.; Damerell, C.; Gibson, M.; Nichols, A.; Stanitzki, M.; Strube, J.; Turchetta, R.; Tyndel, M.; Weber, M.; Worm, S.; Zhang, Z.; Barklow, T.L.; Belymam, A.; Breidenbach, M.; Cassell, R.; Craddock, W.; Deaconu, C.; Dragone, A.; Graf, N.A.; Haller, G.; Herbst, R.; Hewett, J.L.; Jaros, J.A.; Johnson, A.S.; Kim, P.C.; MacFarlane, D.B.; Markiewicz, T.; Maruyama, T.; McCormick, J.; Moffeit, K.; Neal, H.A.; Nelson, T.K.; Oriunno, M.; Partridge, R.; Peskin, M.E.; Rizzo, T.G.; Rowson, P.; Su, D.; Woods, M.; Chakrabarti, S.; Dieguez, A.; Garrido, Ll.; Kaminski, J.; Conway, J.S.; Chertok, M.; Gunion, J.; Holbrook, B.; Lander, R.L.; Tripathi, S.M.; Fadeyev, V.; Schumm, B.A.; Oreglia, M.; Gill, J.; Nauenberg, U.; Oleinik, G.; Wagner, S.R.; Ranjan, K.; Shivpuri, R.; Varner, G.S.; Orava, R.; Van Kooten, R.; Bilki, B.; Charles, M.; Kim, T.J.; Mallik, U.; Norbeck, E.; Onel, Y.; Brau, B.P.; Willocq, S.; Taylor, G.N.; Riles, Keith; Yang, H.-J.; Kriske, R.; Cremaldi, L.; Rahmat, R.; Lastovicka-Medin, G.; Seidel, S.; Hildreth, M.D.; Wayne, M.; Brau, J.E.; Frey, R.; Sinev, N.; Strom, D.M.; Torrence, E.; Banda, Y.; Burrows, P.N.; Devetak, E.; Foster, B.; Lastovicka, T.; Li, Y.-M.; Nomerotski, A.; Riera-Babures, J.; Vilasis-Cardona, X.; Manly, S.; Adeva, B.; Iglesias Escudero, C.; Vazquez Regueiro, P.; Saborido Silva, J.J.; Gallas Torreira, A.; Gao, D.; Jie, W.; Jungfeng, Y.; Li, C.; Liu, S.; Liu, Y.; Sun, Y.; Wang, Q.; Yi, J.; Yonggang, W.; Zhao, Z.; De, K.; Farbin, A.; Park, S.; Smith, J.; White, A.P.; Yu, J.; Lou, X.C.; Abe, T.; Aihara, H.; Iwasaki, M.; Lubatti, H.J.; Band, H.R.; Feyzi, F.; Prepost, R.; Karchin, P.E.; Milstene, C.; Baltay, C.; Dhawan, S.; Kwon, Y.-J.

    2009-01-01

    Letter of intent describing SiD (Silicon Detector) for consideration by the International Linear Collider IDAG panel. This detector concept is founded on the use of silicon detectors for vertexing, tracking, and electromagnetic calorimetry. The detector has been cost-optimized as a general-purpose detector for a 500 GeV electron-positron linear collider.

  9. The Best Use of a Cover Letter

    Institute of Scientific and Technical Information of China (English)

    2005-01-01

    So when should you use a cover letter? Only as part of a limited, targeted campaign to reach potential employers. Take the time to research and understand a company before committing yourself on paper as a potential employee, if you have no idea what the company does,

  10. "Physical Review Letters" in the Classroom

    Science.gov (United States)

    Angiolillo, Paul J.; Lynch, Jonathan

    2010-01-01

    Ask any physicist what the preeminent journal in the field is, and I think the almost unanimous answer will be "Physical Review Letters" ("PRL"). This weekly journal of the American Physical Society publishes high-impact research from all the major subdisciplines of physics. This journal is not the one you would think is the first place a high…

  11. An Open Letter to Ninth Graders

    Science.gov (United States)

    Sullivan, Patrick

    2009-01-01

    Many studies and reports in recent years have argued that there's an important "expectations gap" between the skills students are typically bringing to college and what college teachers think students should be bringing with them to college. This article, presented in the form of an open letter to first-year high school students, is an attempt…

  12. Post-Approval Studies

    Data.gov (United States)

    U.S. Department of Health & Human Services — The CDRH Post-Approval Studies Program encompasses design, tracking, oversight, and review responsibilities for studies mandated as a condition of approval of a...

  13. Letter to President [Laguna Atascosa National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Secretary of the Interior to the President regarding the establishment of the Laguna Atascosa Wilderness area. The letter...

  14. 50 CFR 216.257 - Letters of Authorization.

    Science.gov (United States)

    2010-10-01

    ... ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND IMPORTING OF MARINE... Mexico § 216.257 Letters of Authorization. (a) A Letter of Authorization, unless suspended or...

  15. Letter to President [Back Bay National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Assistant Secretary of the Interior to the President regarding the establishment of the Back Bay Wilderness area. The letter...

  16. Letter to President [Cedar Island National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Assistant Secretary of the Interior to the President regarding the establishment of the Cedar Island Wilderness area. The letter...

  17. Can words be read without abstract letter identities?

    Directory of Open Access Journals (Sweden)

    Simon Fischer-Baum

    2014-04-01

    CH’s acquired dyslexia and dysgraphia left him with a profound impairment in processing abstract letter identities. This impairment affected his ability to process strings of letters in a variety of tasks; for example nonword reading, spelling, recognizing orally spelled words. However, while impaired, his single word reading was surprisingly good given his single letter impairment, suggesting an additional route to word meaning from visually-presented familiar words that does not require abstract letter identities.

  18. 33 CFR 62.43 - Numbers and letters.

    Science.gov (United States)

    2010-07-01

    ... letters. (a) All solid red and solid green aids are numbered, with red aids bearing even numbers and green... 33 Navigation and Navigable Waters 1 2010-07-01 2010-07-01 false Numbers and letters. 62.43... to assist in their identification, or to indicate their purpose. Sidemarks may carry letters...

  19. Transposed-Letter and Laterality Effects in Lexical Decision

    Science.gov (United States)

    Perea, Manuel; Fraga, Isabel

    2006-01-01

    Two divided visual field lexical decision experiments were conducted to examine the role of the cerebral hemispheres in transposed-letter similarity effects. In Experiment 1, we created two types of nonwords: nonadjacent transposed-letter nonwords ("TRADEGIA"; the base word was "TRAGEDIA," the Spanish for "TRAGEDY") and two-letter different…

  20. Letter representations in writing: An fMRI adaptation approach

    Directory of Open Access Journals (Sweden)

    Olivier eDufor

    2013-10-01

    Full Text Available Abstract:Behavioral and neuropsychological research in reading and spelling has provided evidence for the role of the following types of orthographic representations in letter writing: letter forms, letter case, and abstract letter identities. We report on the results of an fMRI investigation designed to identify the neural substrates of these different representational types. Using a neural adaptation paradigm we examined the neural distribution of inhibition and release from inhibition in a letter-writing task in which, on every trial, participants produced three repetitions of the same letter and a fourth letter that was either identical to (no-change trial or different from the previous three (change trial. Change trials involved a change in the shape, case and/or identity of the letter. After delineating the general letter writing network by identifying areas that exhibited significant neural adaptation effects on no-change trials, we used deconvolution analysis to examine this network for effects of release from inhibition on change trials. In this way we identified regions specifically associated with the representation of letter shape (left SFS and SFG/pre-CG and letter identity (left fusiform gyrus or both (cerebellum, post-central gyrus and middle frontal gyrus. No regions were associated with the representation of letter case. This study showcases an investigational approach that allows for the differentiation of the neurotopography of the representational types that are key to our ability to produce written language.

  1. Return to sender: Constantijn Huygens as a man of letters

    NARCIS (Netherlands)

    Gosseye, L.; Blom, F.; Leerintveld, A.

    2013-01-01

    Return to Sender takes as its starting point Constantijn Huygens’ letters and shows us the author in his different guises: intimus of René Descartes, translator of John Donne, collector of art, writer of flirtatious love letters and the author of a long consolatory letter-poem for an ailing friend w

  2. Michael Maier--nine newly discovered letters.

    Science.gov (United States)

    Lenke, Nils; Roudet, Nicolas; Tilton, Hereward

    2014-02-01

    The authors provide a transcription, translation, and evaluation of nine newly discovered letters from the alchemist Michael Maier (1568-1622) to Gebhardt Johann von Alvensleben (1576-1631), a noble landholder in the vicinity of Magdeburg. Stemming from the final year of his life, this correspondence casts new light on Maier's biography, detailing his efforts to secure patronage amid the financial crisis of the early Thirty Years' War. While his ill-fated quest to perfect potable gold continued to form the central focus of his patronage suits, Maier also offered his services in several arts that he had condemned in his printed works, namely astrology and "supernatural" magic. Remarks concerning his previously unknown acquaintance with Heinrich Khunrath call for a re-evaluation of Maier's negotiation of the discursive boundaries between Lutheran orthodoxy and Paracelsianism. The letters also reveal Maier's substantial contribution to a work previously ascribed solely to the English alchemist Francis Anthony.

  3. Culture and subculture in transactional letter writing

    DEFF Research Database (Denmark)

    Shaw, Philip; Okamura, Akiko

    2000-01-01

    with efforts to write such letters by 21 NSE and 23 NNSE non-professionals (British undergraduates and overseas English teachers). The results showed that the non-native professionals by and large perceived the rhetorical demands of the situation similarly to native professionals but were a little less likely...... and language. Thus the teaching approach for writing depends crucially on the status of the learners, and to teach lexical phrases is particularly important for non-natives....

  4. Essay: reflections on Physical Review Letters.

    Science.gov (United States)

    Lazarus, David

    2008-08-01

    During my tenure as APS Editor-in-Chief Physical Review Letters changed from a journal whose authors were mostly from the U.S. to one whose authors were mostly from abroad. I encouraged authors to publicize their work even before their papers were accepted for publication. And I sought to raise the quality of the papers that were published even higher than before.

  5. Your Letters Could Change My Life

    Institute of Scientific and Technical Information of China (English)

    Nancy; Snow

    2007-01-01

    "Your letters could change my life."These words were sent to me by a Chinese student whose lifelong dream is to study in America.I met her in September 2007, just a week after arriving as a visiting pro- fessor at Tsinghua University’s School of Journalism and Communication.She attended a lunch where I was speaking. We exchanged some pleasantries.She e- mailed a follow-up greeting and

  6. Resource Letter QI-1: Quantum Information

    Science.gov (United States)

    Strauch, Frederick W.

    2016-07-01

    This Resource Letter surveys the history and modern developments in the field of quantum information. It is written to guide advanced undergraduates, beginning graduate students, and other new researchers to the theoretical and experimental aspects of this field. The topics covered include quantum states and processes, quantum coding and cryptography, quantum computation, the experimental implementation of quantum information processing, and the role of quantum information in the fundamental properties and foundations of physical theories.

  7. Resource Letter: TE-1: Teaching electronics

    Science.gov (United States)

    Henry, Dennis C.

    2002-01-01

    This Resource Letter examines the evolution, roles, and content of courses in electronics in the undergraduate physics curriculum, and provides a guide to resources for faculty teaching such courses. It concludes with a brief section addressing problems of electromagnetic interference in electronic systems, and provides an introduction to the literature and practice of electromagnetic compatibility. I have included textbooks, reference books, articles, collections of laboratory experiments and projects, sources of equipment and parts, software packages, videos, and websites.

  8. A Retrospective Analysis Comparing the New Standardized Letter of Recommendation in Dermatology with the Classic Narrative Letter of Recommendation.

    Science.gov (United States)

    Kaffenberger, Jessica A; Mosser, Joy; Lee, Grace; Pootrakul, Llana; Harfmann, Katya; Fabbro, Stephanie; Faith, Esteban Fernandez; Carr, David; Plotner, Alisha; Zirwas, Matthew; Kaffenberger, Benjamin H

    2016-09-01

    Background: In an effort to avoid numerous problems associated with narrative letters of recommendation, a dermatology standardized letter of recommendation was utilized in the 2014-2015 resident application cycle. Objective: A comparison of the standardized letter of recommendation and narrative letters of recommendation from a single institution and application cycle to determine if the standardized letter of recommendation met its original goals of efficiency, applicant stratification, and validity. Methods: Eight dermatologists assessed all standardized letters of recommendation/narrative letters of recommendation pairs received during the 2014-2015 application cycle. Five readers repeated the analysis two months later. Each letter of recommendation was evaluated based on a seven question survey. Letter analysis and survey completion for each letter was timed. Results: Compared to the narrative letters of recommendation, the standardized letter of recommendation is easier to interpret (precommendation are also faster to interpret (precommendation (precommendation appears to be meeting its initial goals of 1) efficiency, 2) applicant stratification, and 3) validity. (J Clin Aesthet Dermatol. 2016;9(9):36-2.).

  9. LEXICAL PHRASEOLOGICAL ANALYSIS OF ENGLISH BUSINESS LETTERS

    Directory of Open Access Journals (Sweden)

    Krivoruchko I. S.

    2015-11-01

    Full Text Available The development of international cooperation has promoted the updating of problems connected with business communication effectiveness. These problems are very crucial, because their solution may predetermine the collaboration success of business partners. The integral part of this success is the efficiency of the exchange of textual information. Nowadays the main information exchange method in modern business relations is business correspondence in English; therefore, its research makes an important contribution to the solution of the pressing problem connected with the achievement of some goals in business. In the article, we analyze both general and specific linguistic features of English business letters, which differ them from texts of other fields of human activity. A special attention is paid to the question of the content and presence degree of lexicological and phraseological units in English business letters. In the end the author comes to the conclusion that business communication is considered effective if it contributes to the mutual understanding of partners with the help of the most optimal means. The analysis of practical material showed that these means could be lexicological and phraseological units. The correct choice of these units helps with the formation of those features of a business letter, which would make it effective

  10. Gender differences in recommendation letters for postdoctoral fellowships in geoscience

    Science.gov (United States)

    Dutt, Kuheli; Pfaff, Danielle L.; Bernstein, Ariel F.; Dillard, Joseph S.; Block, Caryn J.

    2016-11-01

    Gender disparities in the fields of science, technology, engineering and mathematics, including the geosciences, are well documented and widely discussed. In the geosciences, despite receiving 40% of doctoral degrees, women hold less than 10% of full professorial positions. A significant leak in the pipeline occurs during postdoctoral years, so biases embedded in postdoctoral processes, such as biases in recommendation letters, may be deterrents to careers in geoscience for women. Here we present an analysis of an international data set of 1,224 recommendation letters, submitted by recommenders from 54 countries, for postdoctoral fellowships in the geosciences over the period 2007-2012. We examine the relationship between applicant gender and two outcomes of interest: letter length and letter tone. Our results reveal that female applicants are only half as likely to receive excellent letters versus good letters compared to male applicants. We also find no evidence that male and female recommenders differ in their likelihood to write stronger letters for male applicants over female applicants. Our analysis also reveals significant regional differences in letter length, with letters from the Americas being significantly longer than any other region, whereas letter tone appears to be distributed equivalently across all world regions. These results suggest that women are significantly less likely to receive excellent recommendation letters than their male counterparts at a critical juncture in their career.

  11. Neural correlates of letter reversal in children and adults.

    Science.gov (United States)

    Blackburne, Liwei King; Eddy, Marianna D; Kalra, Priya; Yee, Debbie; Sinha, Pawan; Gabrieli, John D E

    2014-01-01

    Children often make letter reversal errors when first learning to read and write, even for letters whose reversed forms do not appear in normal print. However, the brain basis of such letter reversal in children learning to read is unknown. The present study compared the neuroanatomical correlates (via functional magnetic resonance imaging) and the electrophysiological correlates (via event-related potentials or ERPs) of this phenomenon in children, ages 5-12, relative to young adults. When viewing reversed letters relative to typically oriented letters, adults exhibited widespread occipital, parietal, and temporal lobe activations, including activation in the functionally localized visual word form area (VWFA) in left occipito-temporal cortex. Adults exhibited significantly greater activation than children in all of these regions; children only exhibited such activation in a limited frontal region. Similarly, on the P1 and N170 ERP components, adults exhibited significantly greater differences between typical and reversed letters than children, who failed to exhibit significant differences between typical and reversed letters. These findings indicate that adults distinguish typical and reversed letters in the early stages of specialized brain processing of print, but that children do not recognize this distinction during the early stages of processing. Specialized brain processes responsible for early stages of letter perception that distinguish between typical and reversed letters may develop slowly and remain immature even in older children who no longer produce letter reversals in their writing.

  12. 75 FR 41262 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving...

    Science.gov (United States)

    2010-07-15

    ...''); Submission via SEC WebForm from Leonard Steiner, Steiner & Libo, P.C., dated May 27, 2010 (``Steiner comments... approve the proposal on an expedited basis. \\12\\ See PIRC letter. ] The Steiner comments suggest limiting... represented by only one attorney.\\13\\ The Steiner comments also ask that: (1) FINRA be ordered to...

  13. Letter-by-letter processing in the phonological conversion of multiletter graphemes: searching for sounds in printed pseudowords.

    Science.gov (United States)

    Peereman, Ronald; Brand, Muriele; Rey, Arnaud

    2006-02-01

    Current models of word reading differ in their descriptions of how print-to-sound conversion is performed. Whereas a parallel procedure is generally assumed, the dual-route cascaded model developed by Coltheart and colleagues (Coltheart, Rastle, Perry, Langdon, and Ziegler, 2001) holds that the nonlexical conversion operates letter by letter, serially from left to right. An interesting aspect of the hypothesized serial procedure is that only the first letter of two-letter graphemes is thought to cause activation of its corresponding phonological code, the second letter of multiletter graphemes being directly merged with the preceding letter to form a complex grapheme. This hypothesis was examined in a task in which participants had to detect target phonemes in visually presented pseudowords. The data suggest that phonological codes associated with all the letters of the multiletter graphemes are activated.

  14. Algoritmi matematici nelle lettere di Gerbert

    Science.gov (United States)

    Rossi, P.

    The content of Gerbert's "scientific" letters is analyzed in detail, with special emphasis on arithmetical and geometrical issues, such as multiplication and division rules related to the use of abacus, superparticular numbers and evaluation of the area of an equilateral triangle. It is shown that Gerbert's area formula, albeit based on rational fractions, could hardly be conceived without knowledge of Pythagoras' theorem. This fact casts a light also on the astronomical tools created by Gerbert, where the didactical aspect cannot be separated from the accuracy of the demonstrations and of the measurements.

  15. Letters to Solovine 1906-1955

    CERN Document Server

    Einstein, Albert

    2011-01-01

    A provocative collection of letters to his longtime friend and translator that spans Einstein's career and reveals the inner thoughts and daily life of a transformative genius From their early days as tutor and scholar, discussing philosophy over Spartan dinners, to their work together to publish Einstein's books in Europe, in Maurice Solovine Einstein found both an engaged mind and a loyal friend. While Einstein frequently shared his observations on science, politics, philosophy, and religion in his correspondence with Solovine, he was just as likely to express his feelings about everyday l

  16. ERP correlates of letter identity and letter position are modulated by lexical frequency

    Science.gov (United States)

    Vergara-Martínez, Marta; Perea, Manuel; Gómez, Pablo; Swaab, Tamara Y.

    2013-01-01

    The encoding of letter position is a key aspect in all recently proposed models of visual-word recognition. We analyzed the impact of lexical frequency on letter position assignment by examining the temporal dynamics of lexical activation induced by pseudowords extracted from words of different frequencies. For each word (e.g., BRIDGE), we created two pseudowords: A transposed-letter (TL: BRIGDE) and a replaced-letter pseudoword (RL: BRITGE). ERPs were recorded while participants read words and pseudowords in two tasks: Semantic categorization (Experiment 1) and lexical decision (Experiment 2). For high-frequency stimuli, similar ERPs were obtained for words and TL-pseudowords, but the N400 component to words was reduced relative to RL-pseudowords, indicating less lexical/semantic activation. In contrast, TL- and RL-pseudowords created from low-frequency stimuli elicited similar ERPs. Behavioral responses in the lexical decision task paralleled this asymmetry. The present findings impose constraints on computational and neural models of visual-word recognition. PMID:23454070

  17. 78 FR 58580 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving...

    Science.gov (United States)

    2013-09-24

    ..., dated July 10, 2013 (``Speyer Letter''); and Leonard Steiner, Attorney, dated July 10, 2013 (``Steiner..., Speyer Letter, St. John's Law Letter, and Steiner Letter. \\13\\ See Buchwalter Letter. \\14\\ See Gitomore Letter, Lipner Letter, Neuman Letter, Speyer Letter, St. John's Law Letter, and Steiner Letter. See...

  18. 50 CFR 216.256 - Applications for Letters of Authorization.

    Science.gov (United States)

    2010-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND... in the Gulf of Mexico § 216.256 Applications for Letters of Authorization. To incidentally...

  19. Writing effective consultation letters: 12 tips for teachers.

    Science.gov (United States)

    Keely, Erin; Dojeiji, Suzan; Myers, Kathryn

    2002-11-01

    Written correspondence is the standard mode of communication between healthcare providers. Despite the importance of this skill and increased emphasis on ambulatory care, communication skills and professionalism in training programs, there has been very little written on the teaching and evaluation of consultation letter writing. Consultation letter writing is an essential skill that cannot be learned simply by reading others' letters and should be taught in a formal manner. This article describes the authors' experience in teaching the skill of writing effective consultation letters to residents and describes strategies for evaluating this skill.

  20. Drugs Approved for Thyroid Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Thyroid Cancer This page lists cancer drugs approved by the ... that are not listed here. Drugs Approved for Thyroid Cancer Cabozantinib-S-Malate Caprelsa (Vandetanib) Cometriq (Cabozantinib-S-Malate) Doxorubicin ...

  1. Drugs Approved for Lung Cancer

    Science.gov (United States)

    ... Ask about Your Treatment Research Drugs Approved for Lung Cancer This page lists cancer drugs approved by the ... listed here. Drugs Approved for Non-Small Cell Lung Cancer Abitrexate (Methotrexate) Abraxane (Paclitaxel Albumin-stabilized Nanoparticle Formulation) ...

  2. Open Letter to the European Commission

    DEFF Research Database (Denmark)

    Savin, Andrej; Schwemer, Sebastian Felix

    2016-01-01

    The recent developments, starting with the Communication on Online Platforms and the Digital Single Market Opportunities and Challenges for Europe released on 25/05/2016, followed by a series of proposals (Proposal for a Directive amending the Audiovisual Media Services Directive, Proposal...... Internet users, namely the rights protected by Articles 8 and 11 of the European Convention of Human Rights. Yet, the proposed Copyright Directive, in particular, seems to negatively affect both the domain and effect of Article 15 of the E-commerce Directive. The signatories of this open letter therefore...... urge the European Commission to take into account the human rights dimension of Article 15 of the E-commerce Directive, as made explicit by the Court of the Justice of the European Union, and to make sure its implications are carefully examined across sectors. Authors: Sophie Stalla-Bourdillon Eleonora...

  3. Original Sin in the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    孙婷

    2012-01-01

    The Scarlet Letter,a representative work of Nathaniel Hawthorne,is a classical novel in American literature of 19th century.It vividly portrays people's life which was greatly influenced by Puritanism and Calvinism.And the author Nathaniel Hawthorne,who lived in that er-a,is also inevitably influenced by these mainstream thoughts.He ex-pressed his black romanticism,black view of human nature and original sin theory in almost each of his work.In his masterpiece,the Scarlet Let-ter,one important theme is original sin.This essay will first analyze where the original sin theory stems from and how it's developed by Hawthorne,and secondly will study how this theory influences the plot and major characters.

  4. NEESPI focus issues in Environmental Research Letters

    Science.gov (United States)

    Norman, Julian; Groisman, Pavel; Soja, Amber J.

    2010-05-01

    In 2007 and 2009 Environmental Research Letters published focus issues (edited by Pavel Groisman and Amber J Soja) made up of work carried out by NEESPI participants. Here, we present the content of those focus issues as an invaluable resource for researchers working in the NEESPI study area. The first of the two issues, published in 2007 with title 'Northern Hemisphere High Latitude Climate and Environmental Change', presents a diverse collection of articles that are assembled into five groups devoted to studies of climate and hydrology, land cover and land use, the biogeochemical cycle and its feedbacks, the cryosphere, and human dimensions. The second issue, published in 2009, with title 'Climatic and Environmental Change in Northern Eurasia' presents diverse, assorted studies of different aspects of contemporary change, representing the diversity of climates and ecosystems across Northern Eurasia.

  5. Boscovich: scientist and man of letters

    Science.gov (United States)

    Proverbio, E.

    Ruggiero Giuseppe Boscovich (1711-1781) is known as one of the most important scientists of the second half of XVIII century, but he was active also as a man of letters, especially through an abundant production of poems in Latin verse. We try to interpret these two, apparently antinomic, aspects of his character in the framework of the culture of his epoch, in which science and literary productions were not considered as two separate or opposite fields, but only two different aspects of human knowledge. In particular we review the field of his poetic production in which this fundamental unity of knowledge is most evident, namely his poems with didactic-scientific subjects, which are examples of high-level popularization of the latest progresses in science (in particular astronomy and Newtonian physics) by means of elegant Latin verse.

  6. Resource Letter BH-2: Black Holes

    CERN Document Server

    Gallo, Elena

    2008-01-01

    This resource letter is designed to guide students, educators, and researchers through (some of) the literature on black holes. Both the physics and astrophysics of black holes are discussed. Breadth has been emphasized over depth, and review articles over primary sources. We include resources ranging from non-technical discussions appropriate for broad audiences to technical reviews of current research. Topics addressed include classification of stationary solutions, perturbations and stability of black holes, numerical simulations, collisions, the production of gravity waves, black hole thermodynamics and Hawking radiation, quantum treatments of black holes, black holes in both higher and lower dimensions, and connections to nuclear and condensed matter physics. On the astronomical end, we also cover the physics of gas accretion onto black holes, relativistic jets, gravitationally red-shifted emission lines, evidence for stellar-mass black holes in binary systems and super-massive black holes at the centers...

  7. A Key to the Art of Letters

    DEFF Research Database (Denmark)

    Jensen-Rix, Robert William

    2008-01-01

    The article examines A. Lane's grammar A Key to the Art of Letters and its contexts. Symbolically published at the threshold to the eighteenth century, Lane presents an unusually bold plan to make English a world language. Although Lane's book holds a key position in the development of English...... grammatical theory, there has been no comprehensive study of its innovative methods and radical proposals for a new national curriculum. Its challenge to Latin and French is analyzed in a historical perspective, and the impact of Lane's ideas during the eighteenth century is traced. The article shows...... that Lane is the first to use English as the basis for writing universal grammar, as part of his strategy to promote English as a universal code for learning and science...

  8. Open Letter to Religious Leaders about Sex Education

    Science.gov (United States)

    American Journal of Sexuality Education, 2011

    2011-01-01

    The "Open Letter to Religious Leaders about Sex Education" reinforces scriptural and theological commitments to truth-telling in calling for "full and honest education about sexual and reproductive health." This "Open Letter" was published in 2002, at about the midpoint of a decade-long federal government commitment to…

  9. Sidebearings analysis of alphabet letters with complex shape

    Directory of Open Access Journals (Sweden)

    Bojan Banjanin

    2014-12-01

    Full Text Available Defining inter-letter space is important part of typeface designing process. The purpose of defining the letter space is to make them visually equally distant from each other within words, sentences and paragraphs creating an even value of grey, without darker or lighter areas. Different approaches for determining letter space were developed in order to facilitate this demanding process. Miguel Sousa (2006 and Walter Tracy (2003 proposes their spacing methods and in paper of De Melo Vargas (2007 and our previous work (Banjanin & Nedeljković, 2014 these methods were tested. The problems occur when defining space around letters a, f, g, s, t, z, and S, for which neither Sousa nor Tracy propose any kind of guidelines (except visual. The aim of this paper is to measure and analyse spacing values for these letters and to see if there is some kind of “formula” or some kind of guidelines which will broaden existing methods in more accurate way. We measured left and right sidebearings of these 7 problematic letters and established additional guidelines for defining letter space of those letters more accurately.

  10. Patient information letters on nutrition: development and implementation.

    NARCIS (Netherlands)

    Binsbergen, J.J. van; Drenthen, A.J.

    2003-01-01

    BACKGROUND: In 1998 the Dutch College of General Practitioners (NHG) began developing patient information letters (PILs), based on the practice guidelines for family physicians (FPs) (NHG standards). Five nutritional guidance letters have since been developed with the Dutch Nutrition Center. METHODS

  11. Character Invention in the Letters of Maimie Pinzer.

    Science.gov (United States)

    Carlson, A. Cheree

    1995-01-01

    Presents a case study of autobiographical letters written by a turn-of-the-century prostitute to a Boston matron. Shows how, in creating a narrative of her life, the author of the letters uses several rhetorical strategies to recreate her character to persuade her audience (and herself) that she is worthy of respect. (SR)

  12. Teaching Braille Letters, Numerals, Punctuation, and Contractions to Sighted Individuals

    Science.gov (United States)

    Putnam, Brittany C.; Tiger, Jeffrey H.

    2015-01-01

    Braille-character recognition is one of the foundational skills required for teachers of braille. Prior research has evaluated computer programming for teaching braille-to-print letter relations (e.g., Scheithauer & Tiger, 2012). In the current study, we developed a program (the Visual Braille Trainer) to teach not only letters but also…

  13. Editorial: acceptance criteria and editorial procedures for Optics Letters

    DEFF Research Database (Denmark)

    Zhang, Xi-Cheng; Andersen, Peter E.; Justus, Brian L.

    2014-01-01

    Optics Letters Editors strive to provide timely reviews and decisions for authors while bringing top quality papers to the optics community. The purpose of this editorial is to explain Optics Letters' acceptance criteria and editorial procedures. Our hope is that greater transparency concerning...

  14. Editorial: acceptance criteria and editorial procedures for Optics Letters.

    Science.gov (United States)

    Zhang, Xi-Cheng; Andersen, Peter E; Justus, Brian L; Galtarossa, Andrea

    2014-09-01

    Optics Letters Editors strive to provide timely reviews and decisions for authors while bringing top quality papers to the optics community. The purpose of this editorial is to explain Optics Letters' acceptance criteria and editorial procedures. Our hope is that greater transparency concerning the decision-making process will increase understanding as well as acceptance of our criteria and procedures.

  15. Editorial: acceptance criteria and editorial procedures for Optics Letters.

    OpenAIRE

    Zhang, Xi-Cheng; Andersen, Peter E.; Justus, Brian L.; Galtarossa, Andrea

    2014-01-01

    Optics Letters Editors strive to provide timely reviews and decisions for authors while bringing top quality papers to the optics community. The purpose of this editorial is to explain Optics Letters' acceptance criteria and editorial procedures. Our hope is that greater transparency concerning the decision-making process will increase understanding as well as acceptance of our criteria and procedures.

  16. Motion Detection, Letter Position Encoding, and Single Word Reading.

    Science.gov (United States)

    Cornelissen, P. L.; Hansen, P. C.

    1998-01-01

    A study involving 48 undergraduates found a link between motion detection and letter-position encoding and a positive relationship, albeit a nonlinear one, between motion detection threshold and the likelihood of making letter errors. This result held when age, IQ, reading age, and phonological awareness were taken into account. (CR)

  17. [The letters of Hermann Rorschach to his brother].

    Science.gov (United States)

    Signer, Rita; Müller, Christian

    2005-01-01

    Hermann Rorschach, brilliant creator of the projective test called after him, worked from the beginning to the middle of 1914 in a sanatorium near Moscow. Recently discovered letters to his brother Paul reveal his motives for abandoning his initial plan to settle in Russia. Apparently the impossibility of scientific work was of great importance. Additional letters complement our knowledge of Rorschach's personality.

  18. Letters to Our Forebears: Reconnecting Generations through Writing.

    Science.gov (United States)

    Okawa, Gail Y.

    2003-01-01

    Proposes that students writing public letters to their forebears might provide a reminder of how individuals and communities can learn from the experience of their foremothers and forefathers. Includes the author's letter to her grandfather, who was imprisoned in internment camps for Japanese Americans during World War II. (PM)

  19. An Approach to the Humanity of the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    Du Feng; Wang qingping

    2009-01-01

    "The Scarlet Letter"is Hawthorne's realist representative.In his masterpiece the Scarlet letter.Hawthorne tells us that all human beings are combination of goodness and evil.As human nature changes between goodness and evil,the science mastered by human beings may bring happiness or pains.

  20. 14 CFR 136.3 - Letters of Authorization.

    Science.gov (United States)

    2010-01-01

    ...) AIR CARRIERS AND OPERATORS FOR COMPENSATION OR HIRE: CERTIFICATION AND OPERATIONS COMMERCIAL AIR TOURS AND NATIONAL PARKS AIR TOUR MANAGEMENT National Air Tour Safety Standards § 136.3 Letters of Authorization. Operators subject to this subpart who have Letters of Authorization may use the...

  1. Letter Position Coding Across Modalities: The Case of Braille Readers

    Science.gov (United States)

    Perea, Manuel; García-Chamorro, Cristina; Martín-Suesta, Miguel; Gómez, Pablo

    2012-01-01

    Background The question of how the brain encodes letter position in written words has attracted increasing attention in recent years. A number of models have recently been proposed to accommodate the fact that transposed-letter stimuli like jugde or caniso are perceptually very close to their base words. Methodology Here we examined how letter position coding is attained in the tactile modality via Braille reading. The idea is that Braille word recognition may provide more serial processing than the visual modality, and this may produce differences in the input coding schemes employed to encode letters in written words. To that end, we conducted a lexical decision experiment with adult Braille readers in which the pseudowords were created by transposing/replacing two letters. Principal Findings We found a word-frequency effect for words. In addition, unlike parallel experiments in the visual modality, we failed to find any clear signs of transposed-letter confusability effects. This dissociation highlights the differences between modalities. Conclusions The present data argue against models of letter position coding that assume that transposed-letter effects (in the visual modality) occur at a relatively late, abstract locus. PMID:23071522

  2. Letter position coding across modalities: the case of Braille readers.

    Directory of Open Access Journals (Sweden)

    Manuel Perea

    Full Text Available BACKGROUND: The question of how the brain encodes letter position in written words has attracted increasing attention in recent years. A number of models have recently been proposed to accommodate the fact that transposed-letter stimuli like jugde or caniso are perceptually very close to their base words. METHODOLOGY: Here we examined how letter position coding is attained in the tactile modality via Braille reading. The idea is that Braille word recognition may provide more serial processing than the visual modality, and this may produce differences in the input coding schemes employed to encode letters in written words. To that end, we conducted a lexical decision experiment with adult Braille readers in which the pseudowords were created by transposing/replacing two letters. PRINCIPAL FINDINGS: We found a word-frequency effect for words. In addition, unlike parallel experiments in the visual modality, we failed to find any clear signs of transposed-letter confusability effects. This dissociation highlights the differences between modalities. CONCLUSIONS: The present data argue against models of letter position coding that assume that transposed-letter effects (in the visual modality occur at a relatively late, abstract locus.

  3. Overt use of a tactile-kinesthetic strategy shifts to covert processing in rehabilitation of letter-by-letter reading.

    Science.gov (United States)

    Lott, Susan Nitzberg; Carney, Aimee Syms; Glezer, Laurie S; Friedman, Rhonda B

    2010-11-01

    BACKGROUND: Letter-by-letter readers identify each letter of the word they are reading serially in left to right order before recognizing the word. When their letter naming is also impaired, letter-by-letter reading is inaccurate and can render even single word reading very poor. Tactile and/or kinesthetic strategies have been reported to improve reading in these patients, but only under certain conditions or for a limited set of stimuli. AIMS: The primary aim of the current study was to determine whether a tactile/kinesthetic treatment could significantly improve reading specifically under normal reading conditions, i.e. reading untrained words presented in free vision and read without overt use of the strategy. METHODS #ENTITYSTARTX00026; PROCEDURES: Three chronic letter-by-letter readers participated in a tactile/kinesthetic treatment aimed at first improving letter naming accuracy (phase 1) and then letter-by-letter reading speed (phase 2). In a multiple case series design, accuracy and speed of reading untrained words without overt use of the trained tactile/kinesthetic strategy was assessed before phase 1, after phase 1 and again after phase 2. OUTCOMES #ENTITYSTARTX00026; RESULTS: All three patients significantly improved both their speed and accuracy reading untrained words without overt use of the trained tactile/kinesthetic strategy. All three patients required the additional practice in phase 2 to achieve significant improvement. Treatment did not target sentence level reading, yet two of the three patients became so adept that they could read entire sentences. CONCLUSIONS: This study replicates previous findings on the efficacy of tactile/kinesthetic treatment for letter-by-letter readers with poor letter naming. It further demonstrates that this treatment can alter cognitive processing such that words never specifically trained can be read in free vision without overtly using the trained strategy. The data suggest that an important element in achieving

  4. Drugs Approved for Retinoblastoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for retinoblastoma. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  5. Drugs Approved for Neuroblastoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for neuroblastoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  6. FWS Approved Acquisition Boundaries

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data layer depicts the external boundaries of lands and waters that are approved for acquisition by the U.S. Fish and Wildlife Service (USFWS) in North America,...

  7. Premarket Approvals (PMA)

    Data.gov (United States)

    U.S. Department of Health & Human Services — Premarket approval by FDA is the required process of scientific review to ensure the safety and effectiveness of all devices classified as Class III devices. An...

  8. FWS Approved Acquisition Boundaries

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This data layer depicts the external boundaries of lands and waters that are approved for acquisition by the U.S. Fish and Wildlife Service (USFWS) in North...

  9. Digit and letter alexia in carbon monoxide poisoning

    Institute of Scientific and Technical Information of China (English)

    Qingyu Shen; Xiaoming Rong; Rui Pan; Ying Peng; Wei Peng; Yamei Tang

    2012-01-01

    This study examined a 24-year-old patient with delayed encephalopathy, who was admitted to hospital with complaints of headache and visual impairment 1 week after acute carbon monoxide poisoning. The results of a visual field assessment, electroencephalography and head magnetic resonance imaging indicated damage to the cerebral cortex. After a 2-week treatment period, the patient had recovered from the visual impairment, but exhibited digit- and letter-reading difficulty. The Chinese aphasia battery and the number and letter battery supplement were conducted. The results revealed that the patient exhibited digit and letter alexia, while the ability to read Chinese characters was preserved. In contrast, the patient exhibited a deficit in Chinese character writing, while number and letter writing remained intact. Following treatment, reading and writing ability was improved and electroencephalographic abnormalities were ameliorated. Overall, our experimental findings demonstrated that delayed encephalopathy following acute carbon monoxide poisoning was characterized by digit and letter alexia.

  10. Automatic adverse drug events detection using letters to the editor.

    Science.gov (United States)

    Yang, Chao; Srinivasan, Padmini; Polgreen, Philip M

    2012-01-01

    We present and test the intuition that letters to the editor in journals carry early signals of adverse drug events (ADEs). Surprisingly these letters have not yet been exploited for automatic ADE detection unlike for example, clinical records and PubMed. Part of the challenge is that it is not easy to access the full-text of letters (for the most part these do not appear in PubMed). Also letters are likely underrated in comparison with full articles. Besides demonstrating that this intuition holds we contribute techniques for post market drug surveillance. Specifically, we test an automatic approach for ADE detection from letters using off-the-shelf machine learning tools. We also involve natural language processing for feature definitions. Overall we achieve high accuracy in our experiments and our method also works well on a second new test set. Our results encourage us to further pursue this line of research.

  11. Peer assessment of outpatient consultation letters – feasibility and satisfaction

    Directory of Open Access Journals (Sweden)

    Dojeiji Suzan

    2007-05-01

    Full Text Available Abstract Background Written correspondence is one of the most important forms of communication between health care providers, yet there is little feedback provided to specialists. The objective of this study was to determine the feasibility and satisfaction of a peer assessment program on consultation letters and to determine inter-rater reliability between family physicians and specialists. Methods A rating scale of nine 5-point Likert scale items including specific content, style items, education value of the letter and an overall rating was developed from a previous validated tool. Nine Internal Medicine specialists/subspecialists from two tertiary care centres submitted 10 letters with patient and physician identifiers removed. Two Internal Medicine specialists, and 2 family physicians from the other centre rated each letter (to protect writer anonymity. A satisfaction survey was sent to each writer and rater after collation of the results. A follow-up survey was sent 6–8 months later. Results There was a high degree of satisfaction with the process and feedback. The rating scale information was felt to be useful and appropriate for evaluating the quality of consultation letters by 6/7 writers. 5/7 seven writers felt that the feedback they received resulted in immediate changes to their letters. Six months later, 6/9 writers indicated they had maintained changes in their letters. Raters rank ordered letters similarly (Cronbach's alpha 0.57–0.84 but mean scores were highly variant. At site 1 there were significant differences in scoring brevity (p Conclusion Most participants found peer assessment of letters feasible and beneficial and longstanding changes occurred in some individuals. Family physicians and specialists appear to have different expectations on some items. Further studies on reliability and validity, with a larger sample, are required before high stakes professional assessments include consultation letters.

  12. Detecting letters and words in prose passages: a test of alternative theoretical accounts of the missing letter effect.

    Science.gov (United States)

    Healy, Alice F; Cunningham, Thomas F

    2014-01-01

    College students searched for either h or the in prose passages in which every h occurred in the test word the. In Experiment 1, passage versions differed in that the critical noun phrases were either the alone (i.e., in citation form as a noun referring to itself) or "the definite article." Many more detection errors occurred for letter than word target items, especially with "the definite article." In Experiment 2, passage versions differed in that a given noun phrase containing the test word the occurred as a subject in one version and an object in the other. Again, many more detection errors occurred when the target item was the letter h than when it was the letter sequence the. Also, with letter but not letter sequence targets, more detection errors occurred for object than subject noun phrases. In Experiment 3, passages were presented either in regular format or with all capital letters. Students made more detection errors with the regular than with the capitals format, many more errors occurred when participants searched for letters than for letter sequences, and the effect of target item was larger with regular than with capitals format. These findings suggest that accounts of detection errors in reading must include the influence of unitization and processing time or attentional allocation.

  13. Six steps to fast-track insurance approval for bariatric surgery.

    Science.gov (United States)

    Frezza, Eldo E

    2006-05-01

    Most of the health-insurers approve bariatric surgery for patients according to the NIH standards, while others only approve the surgery if the patient has a BMI >50. Therefore, it is important for the physician to know and carefully follow the various criteria of different insurance companies. We suggest 6 steps to fast-track insurance approval: 1) a multidisciplinary team; 2) 6-month diet; 3) comprehensive medical evaluation; 4) flexibility and consistency; 5) analysis of each patient indication; 6) quality of cost-effectiveness and long-term monitoring and benefits. In the event that an insurance company rejects the request for surgery, a blueprint of an appeal letter is very important. The appeal letter should stress the indications and benefits of surgery for your patients. Insurance company criteria may differ from the NIH guidelines. Irrespective of this, the steps outlined will help speed the insurance approval process and reduce paperwork and confusion. Most often, rejections stem from letters that were not written clearly or that lacked one or more of the elements delineated above. If the surgeon follows the 6 steps described, he/she should meet less disappointment, as in our experience that went from 50% to 90% success because of better communication with insurance and more appropriate paperwork.

  14. 75 FR 59299 - Self-Regulatory Organizations; NYSE Amex LLC; Order Approving a Proposed Rule Change Amending Its...

    Science.gov (United States)

    2010-09-27

    ... Commission received no comment letters on the proposal. This order approves the proposed rule change. \\1\\ 15... combination with SFTI connections and optic connections to outside access centers and within the data center. The SFTI and optic connections are not related to the co-location services. Amex represented that...

  15. [Darwin in the Republic of Letters].

    Science.gov (United States)

    Bertani, Stefano

    2013-01-01

    For those accustomed to thinking that the modern cultural dimension arose under the banner of a clash between the so-called "two cultures," the figure of Darwin the "humanist" could reserve numerous surprises. It was above all the well-known paleontologist S.J. Gould who pointed them out. He went so far as to track down, in the Italian cultural roots from Saint Francis to Galileo, an element of continuity between his own Darwinism and our literary tradition that passes through the writing of the masterpieces of the nineteenth-century natural sciences. On the basis of a similar, and also audacious, rereading of the cultural history, the essay proposes to indicate some possible developments of the new dialogue undertaken, beginning with the insertion of the scientist Darwin in the European horizon of the Republic of Letters. There are then indicated some historical-cultural categories that would merit reconsideration: the new figure of intellectual of the twenty-first century, the idea of a science immersed in the historical contingency and in the concrete pleasure of the subject that knows, the role of "sweetness" and of "wonder" also in the most rigorous study, and lastly the need of an in-depth knowledge of the Darwinian writing, not as a curiosity for the educational trend of the era of positivism, but as an indispensable epistemological requisite for a correct understanding of its science.

  16. Concurrent cognitive processing and letter sequence transcription deficits in stutterers.

    Science.gov (United States)

    Webster, W G

    1990-03-01

    Previous research has indicated that men who stutter transcribe rapidly presented sequences of letters more slowly and less accurately than nonstutterer controls. Experiment 1 demonstrated that the transcription deficit is not limited to task conditions that demand concurrent monitoring and responding. This was evidenced by comparable deficits on a successive response condition that required subjects to write letters after the presentation was complete. The results of Experiment 2 indicated that the deficit is not due to a difficulty by stutterers in parsing streams of stimulus information internally. Their performance did not differentially improve when letters were grouped with brief pauses, nor with experience in transcribing preparsed letter sequences. This experiment also demonstrated that the phenomenon is generalizable to women. In related testing, stutterers were slower than controls in writing internally generated sequences of letters, those of the alphabet forwards and backwards, but not in writing the same two letters, A and B, repetitively nor in the cognitively more demanding task of writing numbers backwards by three's. These results parallel those obtained with finger tapping of same versus unique sequences by stutterers and were interpreted as being consistent with the idea that while stutterers are not generally slower motorically than nonstutterers, they experience difficulty when required to organize and carry out tasks with new multiple response transitions. The two experiments have replicated and extended, under different conditions, the earlier findings of a letter sequence transcription deficit in stutterers, but the nature of the interference still remains to be clarified.

  17. Novel Moment Features Extraction for Recognizing Handwritten Arabic Letters

    Directory of Open Access Journals (Sweden)

    Gheith Abandah

    2009-01-01

    Full Text Available Problem statement: Offline recognition of handwritten Arabic text awaits accurate recognition solutions. Most of the Arabic letters have secondary components that are important in recognizing these letters. However these components have large writing variations. We targeted enhancing the feature extraction stage in recognizing handwritten Arabic text. Approach: In this study, we proposed a novel feature extraction approach of handwritten Arabic letters. Pre-segmented letters were first partitioned into main body and secondary components. Then moment features were extracted from the whole letter as well as from the main body and the secondary components. Using multi-objective genetic algorithm, efficient feature subsets were selected. Finally, various feature subsets were evaluated according to their classification error using an SVM classifier. Results: The proposed approach improved the classification error in all cases studied. For example, the improvements of 20-feature subsets of normalized central moments and Zernike moments were 15 and 10%, respectively. Conclusion/Recommendations: Extracting and selecting statistical features from handwritten Arabic letters, their main bodies and their secondary components provided feature subsets that give higher recognition accuracies compared to the subsets of the whole letters alone.

  18. Pembrolizumab: first global approval.

    Science.gov (United States)

    Poole, Raewyn M

    2014-10-01

    Pembrolizumab [Keytruda(®) (US)], a humanized monoclonal antibody against the programmed death receptor-1 (PD-1) protein, has been developed by Merck & Co for the treatment of cancer. Pembrolizumab has received its first global approval for the treatment of advanced, unresectable or metastatic malignant melanoma in the US, for use in patients with disease progression after prior treatment with ipilimumab and, for BRAF V600 mutation-positive patients, a BRAF inhibitor. It is the first anti-PD-1 therapy to receive regulatory approval in the US, and is currently under regulatory review in the EU. This article summarizes the milestones in the development of pembrolizumab leading to this first approval for the treatment of malignant melanoma.

  19. Pomalidomide: first global approval.

    Science.gov (United States)

    Elkinson, Shelley; McCormack, Paul L

    2013-05-01

    Pomalidomide (Pomalyst(®)) is a small molecule analogue of thalidomide under development with Celgene Corporation for the oral treatment of haematological and connective tissue diseases. Pomalidomide has been approved in the USA and is awaiting approval in the EU for use with low-dose dexamethasone for the treatment of relapsed and refractory multiple myeloma that has progressed following at least two prior therapies, including lenalidomide and bortezomib. The efficacy and safety of pomalidomide as monotherapy in patients with relapsed and refractory multiple myeloma has also been evaluated in a phase III trial. The agent is in phase III clinical development for the treatment of myelofibrosis and in phase II development for systemic sclerosis. Pomalidomide is also being investigated in patients with amyloidosis, prostate cancer, small cell lung cancer, pancreatic cancer, graft-versus-host disease, and Waldenstrom's macroglobulinaemia. This article summarizes the milestones in the development of pomalidomide leading to this first global approval for relapsed and refractory multiple myeloma.

  20. Apremilast: first global approval.

    Science.gov (United States)

    Poole, Raewyn M; Ballantyne, Anita D

    2014-05-01

    Apremilast (Otezla(®)), an oral small molecule inhibitor of type-4 cyclic nucleotide phosphodiesterase (PDE-4), is under development with Celgene Corporation for the treatment of psoriatic arthritis, psoriasis, ankylosing spondylitis, Behçet's syndrome, atopic dermatitis, and rheumatoid arthritis. Apremilast is indicated for the treatment of active psoriatic arthritis in adults. Apremilast has received its first global approval for this indication in the USA. Regulatory submissions for approval in this indication are under review in Canada and Europe. Regulatory filings have also been submitted for apremilast in the treatment of plaque psoriasis in the USA and Europe. This article summarizes the milestones in the development of apremilast leading to its first approval for the treatment of psoriatic arthritis.

  1. International Large Detector. Letter of intent

    Energy Technology Data Exchange (ETDEWEB)

    Stoeck, Holger [Sydney Univ., NSW (Australia). Falkiner High Energy Physics Group; Bergauer, Thomas; Dragicevic, Marko [Oesterreichische Akademie der Wissenschaften, Vienna (AT). Inst. fuer Hochenergiephysik] (and others)

    2010-07-01

    In the summer of 2007, the GLD concept study group, whose membership was largely based in Asia, and the LDC concept study group, which was mostly based in Europe with a strong north american membership, joined forces to produce a single Letter of Intent for a detector at the International Linear Collider, and formed the ILD concept group. Both the GLD and LDC concepts used the particle flow algorithm for jet reconstruction and a TPC for the central tracker. The basic parameters of the two concepts such as the size of the detector and the strength of the solenoid field, however, were quite different and had to be unified in order to write this letter of intent for ILD. Also, other critical details such as the interaction region design had to be unified. This was a non-trivial task, neither politically nor sociologically. The newly-formed concept study group, the ILD group, created a management team and engaged in intense studies to define the ILD detector concept by scientifically optimising the detector designs. The process has worked remarkably well, and we present here the outcome of this study as well as the large amount of studies that preceded separately by the two older concept groups. The ILD detector concept is now well defined, even though some technology choices are still open. One of the merits of unifying the detector concepts was that it revitalised the studies on physics performance and detector designs. We believe that the level of sophistication of the simulation and physics analyses has reached a high degree of sophistication for a detector group at this stage. This was achieved through collaboration and competition, and is the result of a productive learning process. The unification had also positive effects on the subdetector R and D efforts. Most R and D on detector technologies relevant to the GLD and LDC groups is being performed within the framework of detector R and D collaborations such as LCTPC, SiLC, CALICE, and FCAL which pursue their

  2. Code-switching in letter writing

    Directory of Open Access Journals (Sweden)

    P.S. Sobahle

    2013-02-01

    Full Text Available The study sets out to investigate code switching in letter writing among a small group ofXhosa speaking people. Code switching is found in informal speech and informal writing. It was established from the data that the closer people are, the more code switching there is. Code switching seems to follow a pattern in that it was observed to occur: (a only with certain people (b when talking about certain topics (c when wanting to exclude another person (d when emphasising a point. Code switching also appears to have a 'grammar' of its own. It is not in any way a pidgin. It is clear from the data that code switching does not reflect denial of one's identity. English, being the medium of education for Blacks in South Africa, is therefore bound to be reflected not only in their speech but also in their writing. Die studie het ten doe/ om registeroorskakeling in die skryf van briewe deur 'n klein groepie Xhosasprekendes te ondersoek. Registeroorskakeling word gevind in informele spraak en informele skryfwerk. Daar is uit die data vasgestel dat hoe intiemer mense is hoe meer vind registeroorskakeling plaas. Volgens waarneming blyk dit dat registeroorskakeling 'n patroon volg, want dit het voorgekom: (a net by sekere mense (b wanneer oor sekere onderwerpe gepraat is (c wanneer 'n ander per soon uitgeskakel is (d wanneer 'n mening beklemtoon is. Registeroorskakeling blyk 'n eie grammatika te he. Dit is geensins "pidgin" nie. Dit blyk uit data dat die skrywer se identiteit nie verlore raak tydens registeroorskakeling nie. Omdat Engels die medium van onderrig vir Swartes in Suid-Afrika is, sal dit noodwendig nie net in hulle spraak nie, maar ook in hul skryfwerk gereflekteer word.

  3. 78 FR 7784 - Health Information Technology Policy Committee Nomination Letters

    Science.gov (United States)

    2013-02-04

    ... From the Federal Register Online via the Government Publishing Office GOVERNMENT ACCOUNTABILITY OFFICE Health Information Technology Policy Committee Nomination Letters AGENCY: Government... Recovery and Reinvestment Act of 2009 (ARRA) established the Health Information Technology Policy...

  4. Politeness Strategies in Good-news Business Letters

    Institute of Scientific and Technical Information of China (English)

    毕争; 李纳

    2008-01-01

    This paper analyzes the presentation of politeness in good-news business letters at the lexical,syntactic,and discourse levels based on Leech's Politeness Principle and Brown and Levinson's Face-saving Theory.

  5. Sept 2013 NFHL Letter of Map Revision (LOMR)

    Data.gov (United States)

    Earth Data Analysis Center, University of New Mexico — The National Flood Hazard Layer (NFHL) data incorporates all Digital Flood Insurance Rate Map(DFIRM) databases published by FEMA, and any Letters Of Map Revision...

  6. 50 CFR 216.259 - Modifications to Letters of Authorization.

    Science.gov (United States)

    2010-10-01

    ... ATMOSPHERIC ADMINISTRATION, DEPARTMENT OF COMMERCE MARINE MAMMALS REGULATIONS GOVERNING THE TAKING AND... in the Gulf of Mexico § 216.259 Modifications to Letters of Authorization. (a) Except as provided...

  7. [Letter of Concurrence : Meredosia National Wildlife Refuge Sport Fishing Plan

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This letter states that the Illinois Department of Conservation concurs with Meredosia NWR's efforts to establish a public use program on the Refuge.

  8. Toward a statistical mechanics of four letter words

    CERN Document Server

    Stephens, Greg J

    2008-01-01

    We consider words as a network of interacting letters, and approximate the probability distribution of states taken on by this network. Despite the intuition that the rules of English spelling are highly combinatorial (and arbitrary), we find that maximum entropy models consistent with pairwise correlations among letters provide a surprisingly good approximation to the full statistics of four letter words, capturing ~92% of the multi-information among letters and even "discovering" real words that were not represented in the data from which the pairwise correlations were estimated. The maximum entropy model defines an energy landscape on the space of possible words, and local minima in this landscape account for nearly two-thirds of words used in written English.

  9. Consultation letters for medically unexplained physical symptoms in primary care

    NARCIS (Netherlands)

    Hoedeman, Rob; Blankenstein, Annette H.; van der Feltz-Cornelis, Christina M.; Krol, Boudien; Stewart, Roy; Groothoff, Johan W.; van der Feltz-Cornelis, CM

    2010-01-01

    Background In primary care between 10% and 35% of all visits concern patients with medically unexplained physical symptoms (MUPS). MUPS are associated with high medical consumption, significant disabilities and psychiatricmorbidity. Objectives To assess the effectiveness of consultation letters (CLs

  10. Love letters to the dead: resurrecting an epistolary art.

    Science.gov (United States)

    Lander, Dorothy A; Graham-Pole, John R

    This article explores the art of letter-writing, specifically to our beloved dead, as a form of autoethnographic research, pedagogy, and care work. As university teachers and qualitative researchers in palliative and end-of-life care, we review the literature and history of epistolary communications with the deceased, as a prelude to writing our own letters. John writes to his long-dead mother and Dorothy to her recently deceased spouse Patrick, each letter followed by a reflective dialogue between us. Through this dialogue, we highlight the potential application of this art, or handcraft, to formal and informal palliative care, and the implications for practice, pedagogy, policy, and research. We propose that such direct, non-mediated, communications can offer a valuable form of healing for bereaved people. The therapeutic potential of letter writing and the abundance of literary and popular culture exemplars of responses from the dead are also largely unexplored in death education and research.

  11. Resource Letter PE-1: Physics and the Environment

    Science.gov (United States)

    Shonle, John I.

    1974-01-01

    Presents a Resource Letter on air pollution, noise pollution, transportation, and solid waste for the purpose of acquainting college physicists with some of the literature and teaching aids. Included are five bibliographies of which four are annotated. (CC)

  12. Letter from Federal Power Commission [Havasu National Wildlife Refuge

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — This document is a letter from the Federal Power Commission to the Secretary of the Interior. It confirms that the Federal Power Commission has no plans that...

  13. Name-letter branding under scrutiny: real products, new algorithms, and the probability of buying.

    Science.gov (United States)

    Stieger, Stefan

    2010-06-01

    People like letters matching their own first and last name initials more than nonname letters. This name-letter effect has also been found for brands, i.e., people like brands resembling their own name letters (initial or first three). This has been termed name-letter branding effect. In the present study of 199 participants, ages 12 to 79 years, this name-letter branding effect was found for a modified design (1) using real products, (2) concentrating on product names rather than brand names, (3) using five different products for each letter of the Roman alphabet, (4) asking for the buying probability, and (5) using recently introduced algorithms, controlling for individual response tendencies (i.e., liking all letters more or less) and general normative popularity of particular letters (i.e., some letters are generally preferred more than other letters).

  14. Politeness Strategies in English and Chinese Business Letters

    Institute of Scientific and Technical Information of China (English)

    查琳琳

    2014-01-01

    This paper explores similarities and differences in the application of positive and negative politeness strategies to Eng-lish and Chinese business letters and illuminates underlying causes of such similarities and differences. The results indicate that English and Chinese business letters have some common features and great discrepancies in categories and the distribution of posi-tive and negative politeness strategies. It is argued that common situational factors, different cultural backgrounds and different syntactic features result in their similarities and differences.

  15. On a Field, Sable, the Letter A, Gules——Comments on The Scarlet Letter%On a Field, Sable, the Letter A, Gules--Comments on The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    王瑾

    2007-01-01

    Nathaniel Hawthorne's The Scarlet Letter is a moral and psychological novel which focuses on human nature and the effects of sin. This paper is divided into two parts. The first part focuses on the analysis ofa sable field and the second part is about gules letter A. Actually the two parts are the answers to where the sin is and how to achieve redemption. Hawthorne's thoughts,good wishes and artistic characters are fully expressed in it.

  16. FDA Approval for Imiquimod

    Science.gov (United States)

    On July 15, 2004, the U.S. Food and Drug Administration (FDA) announced the approval of a new indication for Aldara® (imiquimod) topical cream for the treatment of superficial basal cell carcinoma (sBCC), a type of skin cancer.

  17. The effects of alphabet and expertise on letter perception.

    Science.gov (United States)

    Wiley, Robert W; Wilson, Colin; Rapp, Brenda

    2016-08-01

    Long-standing questions in human perception concern the nature of the visual features that underlie letter recognition and the extent to which the visual processing of letters is affected by differences in alphabets and levels of viewer expertise. We examined these issues in a novel approach using a same-different judgment task on pairs of letters from the Arabic alphabet with 2 participant groups: 1 with no prior exposure to Arabic and 1 with reading proficiency. Hierarchical clustering and linear mixed-effects modeling of reaction times and accuracy provide evidence that both the specific characteristics of the alphabet and observers' previous experience with it affect how letters are perceived and visually processed. The findings of this research further our understanding of the multiple factors that affect letter perception and support the view of a visual system that dynamically adjusts its weighting of visual features as expert readers come to more efficiently and effectively discriminate the letters of the specific alphabet they are viewing. (PsycINFO Database Record

  18. A linguistic kaleidoscope of the Malay letter; The case of the eighteenth century official letters from the Sultanate of Buton

    Directory of Open Access Journals (Sweden)

    S. Suryadi

    2015-07-01

    Full Text Available The Malay letters make up the largest category of documents among the Malay manuscripts preserved at Leiden University Library, the Netherlands. The corpus represents the scope of the territories under Dutch East Indies authority during the colonial era. In fact, they are authentic documents which denote not only political contact between the local kingdoms in the Archipelago (Nusantara with the Dutch East Indies government in Batavia during colonial times but also constitute an important source for the study of the historical development of the Malay language. This essay looks at the language characters of such letters which came from the court of Buton in Southeast Sulawesi. It aims to sketch the linguistic variety of the classical Malay language represented in its eighteenth century letter-writing tradition. Having specific diction and features that confirm local influences, the language of the letters shows distinctiveness in terms of phonology, morphology and syntax.

  19. Letters to those who Dare Feel: Using Reflective Letter-Writing to Explore the Emotionality of Research

    Directory of Open Access Journals (Sweden)

    Kathleen Pithouse-Morgan

    2012-02-01

    Full Text Available Using reflective letter-writing as a method of generating data, a group of four researchers embarked on a collaborative autoethnographic inquiry into the emotional dimensions of researching social aspects of HIV & AIDS. In this article, we use the medium of a narrative dialogue to represent and re-examine our reflective letter-writing method. The dialogue draws attention to key features of reflective letter-writing as a collaborative autoethnographic research method and, in so doing, highlights and explores the nature, potential significance, and challenges of this method. Our discussion points to the value of a collaborative process of reflective letter-writing as a way for researchers to access and portray emotional aspects of their research experience, to deepen their engagement with these emotional dimensions, and to gain insight into their own and others' lived research experiences.

  20. Letter - Reply: Meteors in Australian Aboriginal Dreamings

    Science.gov (United States)

    Hamacher, Duane W.

    2011-06-01

    In response to the letter by Gorelli (2010) about Hamacher & Norris (2010), he is quite right about Aboriginal people witnessing impact events in Australia. There are several oral traditions regarding impact sites, some of which were probably witnessed, as Gorelli pointed out. The Henbury craters he mentions, with a young age of only ∼ 4200 years, have oral traditions that seem to describe a cosmic impact, including an aversion to drinking water that collects in the craters in fear that the fire-devil (which came from the sun, according to an Elder) would rain iron in them again. Other impact sites, such as Gosse's Bluff crater (Tnorala in the Arrernte language) and Wolfe Creek crater (Kandimalal in the Djaru language) have associated impact stories, despite their old ages (142 Ma and ∼0.3 Ma, respectively). In addition, many fireball and airburst events are described in Aboriginal oral traditions, a number of which seem to indicate impact events that are unknown to Western science. I have published a full treatise of meteorite falls and impact events in Australian Aboriginal culture that I would like to bring to the attention of Gorelli and WGN readers (Hamacher & Norris, 2009). Although our paper was published in the 2009 volume of Archaeoastronomy, it did not appear in print until just recently, which is probably why it has gone unnoticed. Recent papers describing the association between meteorites and Aboriginal cosmology (Hamacher, 2011) and comets in Aboriginal culture (Hamacher & Norris, 2011) have also been published, and would likely be of interest to WGN readers. I heartily agree with Gorelli that oral traditions are fast disappearing, taking with them a wealth of information about not only that peoples' culture, but also about past geologic and astronomical events, such as meteorite falls and cosmic impacts (a branch of the growing field of Geomythology). There is an old saying that "when a man dies, a library goes with him". This is certainly the

  1. 78 FR 21449 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving...

    Science.gov (United States)

    2013-04-10

    ... & Kantas, dated Feb. 7, 2013 (``Shepherd Letter''); letter from Leonard Steiner, Beverly Hills, California, dated Feb. 7, 2013 (``Steiner Letter''); letter from Joseph Fogel, Fogel & Associates, dated Feb....

  2. Using Incremental Rehearsal to Teach Letter Sounds to English Language Learners

    Science.gov (United States)

    Rahn, Naomi L.; Wilson, Jennifer; Egan, Andrea; Brandes, Dana; Kunkel, Amy; Peterson, Meredith; McComas, Jennifer

    2015-01-01

    This study examined the effects of incremental rehearsal (IR) on letter sound expression for one kindergarten and one first grade English learner who were below district benchmark for letter sound fluency. A single-subject multiple-baseline design across sets of unknown letter sounds was used to evaluate the effect of IR on letter-sound expression…

  3. Linking the Shapes of Alphabet Letters to Their Sounds: The Case of Hebrew

    Science.gov (United States)

    Treiman, Rebecca; Levin, Iris; Kessler, Brett

    2012-01-01

    Learning the sounds of letters is an important part of learning a writing system. Most previous studies of this process have examined English, focusing on variations in the phonetic iconicity of letter names as a reason why some letter sounds (such as that of b, where the sound is at the beginning of the letter's name) are easier to learn than…

  4. Pseudo-synesthesia through reading books with colored letters.

    Directory of Open Access Journals (Sweden)

    Olympia Colizoli

    Full Text Available BACKGROUND: Synesthesia is a phenomenon where a stimulus produces consistent extraordinary subjective experiences. A relatively common type of synesthesia involves perception of color when viewing letters (e.g. the letter 'a' always appears as light blue. In this study, we examine whether traits typically regarded as markers of synesthesia can be acquired by simply reading in color. METHODOLOGY/PRINCIPAL FINDINGS: Non-synesthetes were given specially prepared colored books to read. A modified Stroop task was administered before and after reading. A perceptual crowding task was administered after reading. Reading one book (>49,000 words was sufficient to induce effects regarded as behavioral markers for synesthesia. The results of the Stroop tasks indicate that it is possible to learn letter-color associations through reading in color (F(1, 14 = 5.85, p = .030. Furthermore, Stroop effects correlated with subjective reports about experiencing letters in color (r(13 = 0.51, p = .05. The frequency of viewing letters is related to the level of association as seen by the difference in the Stroop effect size between upper- and lower-case letters (t(14 = 2.79, p = .014 and in a subgroup of participants whose Stroop effects increased as they continued to read in color. Readers did not show significant performance advantages on the crowding task compared to controls. Acknowledging the many differences between trainees and synesthetes, results suggest that it may be possible to acquire a subset of synesthetic behavioral traits in adulthood through training. CONCLUSION/SIGNIFICANCE: To our knowledge, this is the first evidence of acquiring letter-color associations through reading in color. Reading in color appears to be a promising avenue in which we may explore the differences and similarities between synesthetes and non-synesthetes. Additionally, reading in color is a plausible method for a long-term 'synesthetic' training program.

  5. Preventive letter: doubling the return rate after gestational diabetes mellitus.

    Science.gov (United States)

    Olmos, Pablo R; Borzone, Gisella R; Berkowitz, Loni; Mertens, Nicolás; Busso, Dolores; Santos, José L; Poblete, José A; Vera, Claudio; Belmar, Cristián; Goldenberg, Denisse; Samith, Bárbara; Acosta, Ana M; Escalona, Manuel

    2015-05-01

    To measure the impact of a "Preventive Letter" designed to encourage the return of gestational diabetes mellitus (GDM) mothers to follow up visit after delivery, in the context of a worldwide concern about low return rates after delivery of these patients. Mothers with GDM require medical evaluation and an oral glucose tolerance test (OGTT) 6 weeks after delivery, in order to: [a] confirm remission of GDM and [b] provide advice on the prevention of type 2 diabetes. In the year 2003 we developed a "Preventive Letter", containing three aspects: [a] current treatment, [b] suggested management during labor, and [c] a stapled laboratory order for OGTT to be performed 6 weeks after delivery. The return rate after delivery was assessed in two groups of GDM mothers: [a] "Without Preventive Letter" (n = 253), and "With Preventive Letter" (n = 215). Both groups, similar with respect to age (33.0 ± 5.4 and 32.3 ± 4.9 years respectively, p = 0.166) and education time (14.9 ± 1.8 and 15.0 ± 1.8 years respectively, p = 0.494), showed a significant difference in the 1-year return rate after delivery, as assessed by the Kaplan-Meier test: 32.0 % for the group "Without Preventive Letter", and 76.0 % for the group "With Preventive Letter" (p return rate after delivery of GDM mothers was 2.4 times higher in the group "With Preventive Letter" than in the group without it. We believe that this low-cost approach could be useful in other institutions caring for pregnant women with diabetes.

  6. Linaclotide: first global approval.

    Science.gov (United States)

    McWilliams, Vanessa; Whiteside, Glenn; McKeage, Kate

    2012-11-12

    Linaclotide is a once-daily, orally administered, first-in-class agonist of guanylate cyclase-C that is minimally absorbed. It is being developed to treat gastrointestinal disorders by Ironwood Pharmaceuticals and its partners, Forest Laboratories (North America), Almirall (Europe) and Astellas Pharma (Asia-Pacific). Linaclotide has received its first global approval in the US for the treatment of constipation-predominant irritable bowel syndrome (IBS-C) and chronic idiopathic constipation (CIC), and a marketing submission has been filed in the EU for IBS-C. This article summarizes the milestones in the development of linaclotide leading to this first approval for IBS-C and CIC. This profile has been extracted and modified from the Adis R&D Insight drug pipeline database. Adis R&D Insight tracks drug development worldwide through the entire development process, from discovery, through pre-clinical and clinical studies to market launch.

  7. Pitolisant: First Global Approval.

    Science.gov (United States)

    Syed, Yahiya Y

    2016-09-01

    Pitolisant (Wakix™) is an inverse agonist of the histamine H3 receptor that is being developed by Bioproject. Oral pitolisant is approved in the EU for the treatment of narcolepsy with or without cataplexy in adults. Pitolisant has received a Temporary Authorization of Use in France for this indication in case of treatment failure, intolerance or contraindication to currently available treatment. Pitolisant has orphan drug designation in the EU and the USA. In the pivotal HARMONY I trial, pitolisant significantly decreased excessive daytime sleepiness versus placebo in adults with narcolepsy with or without cataplexy (primary endpoint). Pitolisant also significantly decreased cataplexy rate versus placebo in these patients. This article summarizes the milestones in the development of pitolisant leading to this first approval for narcolepsy.

  8. THE EFFECTS OF WORD FAMILIARITY AND LETTER STRUCTURE FAMILIARITY ON THE PERCEPTION OF WORDS

    Science.gov (United States)

    An experiment was conducted to test the hypothesis that familiarity of letter structure (as opposed to familiarity of the word ) would facilitate the...perception of the word . The results showed an interaction between letter structure familiarity and work familiarity such that while letter structure...familiarity facilitated correct identification of the letters of the word , letter structure familiarity resulted in inhibiting the perception of

  9. Baricitinib: First Global Approval.

    Science.gov (United States)

    Markham, Anthony

    2017-03-13

    Baricitinib (Olumiant™) is an orally-administered, small-molecule, janus-associated kinase (JAK) inhibitor developed by Eli Lilly and Incyte Corporation for the treatment of rheumatoid arthritis (RA), atopic dermatitis and systemic lupus erythematosus. JAKs transduce intracellular signals from cell surface receptors for various cytokines and growth factors involved in inflammation and immune function, suggesting JAK inhibitors may be of therapeutic benefit in inflammatory conditions. In February 2017, baricitinib was approved in the EU, as monotherapy or in combination with methotrexate, for the treatment of moderate to severe active rheumatoid arthritis in adult patients who have responded inadequately to, or who are intolerant to one or more disease-modifying anti-rheumatic drugs (DMARDs). Regulatory approval to market baricitinib as a treatment for RA has also been sought in the USA and Japan. This article summarizes the milestones in the development of baricitinib leading to this first global approval for the treatment for moderate to severe active RA in adult patients who have responded inadequately to, or are intolerant to one or more DMARDs.

  10. Evolocumab: First Global Approval.

    Science.gov (United States)

    Markham, Anthony

    2015-09-01

    Evolocumab (Repatha™) is a fully human monoclonal antibody developed by Amgen that has been approved as a treatment for hypercholesterolaemia in the EU, and is awaiting approval in the USA and Japan. It specifically binds proprotein convertase subtilisin/kexin type 9 (PCSK9)-a negative regulator of low-density lipoprotein (LDL)-receptors-thereby improving the ability of the liver to bind LDL-cholesterol (LDL-C), leading to reduced LDL-C blood levels. The drug reduces LDL-C levels in patients with hypercholesterolaemia when used as monotherapy or in conjunction with a statin. This article summarizes the milestones in the development of evolocumab leading to this approval for the treatment of adults with primary hypercholesterolaemia (heterozygous familial and non-familial) or mixed dyslipidaemia as an adjunct to diet with or without a statin and/or other lipid lowering therapies, and in adults and adolescents aged ≥12 years with homozygous familial hypercholesterolaemia in combination with other lipid lowering therapies.

  11. Extra-large letter spacing improves reading in dyslexia.

    Science.gov (United States)

    Zorzi, Marco; Barbiero, Chiara; Facoetti, Andrea; Lonciari, Isabella; Carrozzi, Marco; Montico, Marcella; Bravar, Laura; George, Florence; Pech-Georgel, Catherine; Ziegler, Johannes C

    2012-07-10

    Although the causes of dyslexia are still debated, all researchers agree that the main challenge is to find ways that allow a child with dyslexia to read more words in less time, because reading more is undisputedly the most efficient intervention for dyslexia. Sophisticated training programs exist, but they typically target the component skills of reading, such as phonological awareness. After the component skills have improved, the main challenge remains (that is, reading deficits must be treated by reading more--a vicious circle for a dyslexic child). Here, we show that a simple manipulation of letter spacing substantially improved text reading performance on the fly (without any training) in a large, unselected sample of Italian and French dyslexic children. Extra-large letter spacing helps reading, because dyslexics are abnormally affected by crowding, a perceptual phenomenon with detrimental effects on letter recognition that is modulated by the spacing between letters. Extra-large letter spacing may help to break the vicious circle by rendering the reading material more easily accessible.

  12. Melanie Klein's letters addressed to Marcelle Spira (1955-1960).

    Science.gov (United States)

    Quinodoz, Jean-Michel

    2009-12-01

    Between 1955 and 1960, Melanie Klein wrote some 45 hitherto unpublished letters to Marcelle Spira, the Swiss psychoanalyst living at that time in Geneva. In 2006, after Spira's death, these letters were deposited with the Raymond de Saussure Psychoanalysis Centre in Geneva. They are the only known letters that Klein addressed to her psychoanalyst colleagues. Several topics are mentioned in them: (1) the meetings between the two women in Geneva and London; (2) Spira's contribution to Boulanger's translation into French of The Psychoanalysis of Children, which Klein herself carefully revised; (3) the papers that Klein was at that time working on, including Envy and Gratitude; (4) Spira's own work; (5) the difficulties that Spira, a Kleinian psychoanalyst who trained in Buenos Aires, was encountering in her attempt to be admitted to the Swiss Psychoanalytical Society; and (6) a few items of personal and family news. In addition to the invaluable historical information that these letters provide, they offer us a very moving epistolary self-portrait of Melanie Klein, enabling us to discover her personality in the final years of her life - she died in September 1960, just two months after writing her last letter to Spira.

  13. Written work: the social functions of Research Ethics Committee letters.

    Science.gov (United States)

    Dixon-Woods, Mary; Angell, Emma; Ashcroft, Richard E; Bryman, Alan

    2007-08-01

    Research Ethics Committees (RECs) are increasingly institutionalised as a feature of research practice, but have remained strangely neglected by social scientists. In this paper, we argue that analysis of letters from RECs to researchers offers important insights into how RECs operate. We report a traditional content analysis and an ethnographic content analysis of 141 letters to researchers, together with an analysis of the organisational and institutional arrangements for RECs in the UK. We show that REC letters perform three important social functions. First, they define what is deemed by a REC to be ethical practice for any particular application, and confer authority on that definition. They do this actively, through comments on particular aspects of proposals, and passively, through silences about other aspects. Second, they provide an account of the work of the REC, and function as a form of institutional display. Third, they specify the nature of the relationship between the REC and the applicant, casting the applicant in a supplicant role and requiring forms of docility. Writing and reading REC letters require highly specific competences, and engage both parties in a Bourdieusian "game" that discourages challenges from researchers. The authority of RECs' decisions derives not from their appeal to the moral superiority of any ethical position, but through their place in the organisational structure and the social positioning of the parties to the process thus implied. Letters are the critical point at which RECs act on researchers and their projects.

  14. Detection and identification of crowded mirror-image letters in normal peripheral vision.

    Science.gov (United States)

    Chung, Susana T L

    2010-02-01

    Performance for discriminating single mirror-image letters in peripheral vision can be as good as that in central vision, provided that letter size is scaled appropriately [Higgins, K. E., Arditi, A., & Knoblauch, K. (1996). Detection and identification of mirror-image letter pairs in central and peripheral vision. Vision Research, 36, 331-337]. In this study, we asked whether or not there is a reduction in performance for discriminating mirror-image letters when the letters are flanked closely by other letters, compared with unflanked (single) letters; and if so, whether or not this effect is greater in peripheral than in central vision. We compared contrast thresholds for detecting and identifying mirror-image letters "b" and "d" for a range of letter separations, at the fovea and 10 degrees eccentricity, for letters that were scaled in size. For comparison, thresholds were also determined for a pair of non-mirror-image letters "o" and "x". Our principal finding is that there is an additional loss in sensitivity for identifying mirror-image letters ("bd"), compared with non-mirror-image letters ("ox"), when the letters are flanked closely by other letters. The effect is greater in peripheral than central vision. An auxiliary experiment comparing thresholds for letters "d" and "q" vs. "b" and "d" shows that the additional loss in sensitivity for identifying crowded mirror-image letters cannot be attributed to the similarity in letter features between the two letters, but instead, is specific to the axis of symmetry. Our results suggest that in the presence of proximal objects, there is a specific loss in sensitivity for processing broad-band left-right mirror images in peripheral vision.

  15. A Novel Handwritten Letter Recognizer Using Enhanced Evolutionary Neural Network

    Science.gov (United States)

    Mahmoudi, Fariborz; Mirzashaeri, Mohsen; Shahamatnia, Ehsan; Faridnia, Saed

    This paper introduces a novel design for handwritten letter recognition by employing a hybrid back-propagation neural network with an enhanced evolutionary algorithm. Feeding the neural network consists of a new approach which is invariant to translation, rotation, and scaling of input letters. Evolutionary algorithm is used for the global search of the search space and the back-propagation algorithm is used for the local search. The results have been computed by implementing this approach for recognizing 26 English capital letters in the handwritings of different people. The computational results show that the neural network reaches very satisfying results with relatively scarce input data and a promising performance improvement in convergence of the hybrid evolutionary back-propagation algorithms is exhibited.

  16. Letters from ainsworth: contesting the 'organization' of attachment.

    Science.gov (United States)

    Landa, Sophie; Duschinsky, Robbie

    2013-05-01

    As Main (1999) noted in her obituary for Mary Ainsworth, 'she was interacting weekly by letter and manuscript with her mentor and friend, John Bowlby, and their academic correspondence formed an important part of her, and implicitly our, life.' These letters of Ainsworth to John Bowlby during the 1980s, available in the Wellcome Trust Library in London, contain valuable reflections on the work of her pupils to extend her system of classifying infant behaviour in the Strange Situation Procedure. Mary Main proposed a D classification and interpreted such behaviour as a breakdown in an ABC strategy caused by a conflict between a disposition to approach and flee from the caregiver. Patricia Crittenden extended the subtypes of A and C, using a developmental model of information processing, and observed that they could be used together in A/C combinations. These letters offer insight into Ainsworth's intellectual rationale for encouraging both Main and Crittenden in their conflicting endeavours.

  17. Spatial representations of numbers and letters in children

    Directory of Open Access Journals (Sweden)

    Jan eLonnemann

    2013-08-01

    Full Text Available Different lines of evidence suggest that children’s mental representations of numbers are spatially organized in form of a mental number line. It is, however, still unclear whether a spatial organization is specific for the numerical domain or also applies to other ordinal sequences in children. In the present study, children (n = 129 aged 8-9 years were asked to indicate the midpoint of lines flanked by task-irrelevant digits or letters. We found that the localization of the midpoint was systematically biased towards the larger digit. A similar, but less pronounced, effect was detected for letters with spatial biases towards the letter succeeding in the alphabet. Instead of assuming domain-specific forms of spatial representations, we suggest that ordinal information expressing relations between different items of a sequence might be spatially coded in children, whereby numbers seem to convey this kind of information in the most salient way.

  18. The Archetypes of the Characters in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    成程

    2015-01-01

    Nathaniel Hawthorne and his works are deeply influenced by the religion and the Holy Bible.It has many corresponding relationships between the Biblical allusions and the characters,plot and theme in the Scarlet Letter.Hawthorne gave the novel symbolic characters in order to give this symbolism novel a deeper connotation,by borrowing quite a lot of the Biblical allusions.The Scarlet Letter established Hawthorne as the most important 19th century romantic novelist in the United States.This paper attempts to analyze the characteristics and the life experience of the figures in the novel,such as Hester Prynne,Chillingworth,Dimmesdale and Pearl by using the archetypal criticism.The paper also will compare the novel to the Holy Bible so that we canfind the archetypes of the Holy Bible hidden in the Scarlet Letter.

  19. The Archetypes of the Characters in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    成程

    2015-01-01

    Nathaniel Hawthorne and his works are deeply influenced by the religion and the Holy Bible.It has many corresponding relationships between the Biblical allusions and the characters,plot and theme in the Scarlet Letter.Hawthorne gave the novel symbolic characters in order to give this symbolism novel a deeper connotation,by borrowing quite a lot of the Biblical allusions.The Scarlet Letter established Hawthorne as the most important 19 th century romantic novelist in the United States.This paper attempts to analyze the characteristics and the life experience of the figures in the novel,such as Hester Prynne,Chillingworth,Dimmesdale and Pearl by using the archetypal criticism.The paper also will compare the novel to the Holy Bible so that we can find the archetypes of the Holy Bible hidden in the Scarlet Letter.

  20. Romanian letter-writing: a cultural-rhetorical perspective (II

    Directory of Open Access Journals (Sweden)

    Gabriela-Iuliana Morcov

    2016-08-01

    Full Text Available The article aims at revealing the features of Romanian letter-writing during its stages of formation and consolidation. The structural and the stylistic analysis of letters is carried out with regard to the composition of the documents written in Old Romanian according to the requirements imposed by the Slavonic template and with regard to the rhetorical division of the three styles: the simple style, the middle style and the grand style. The description of the Old Romanian epistolary style is based on a taxonomy inspired by Roman Jakobson’s functional communicative model (1964. Following the six factors identified by Jakobson, letters are classified according to the socio-cultural status and the communicative competence of the addresser and of the addressee and in line with the context, the channel and the linguistic code used to write them.

  1. Musical expertise affects neural bases of letter recognition.

    Science.gov (United States)

    Proverbio, Alice Mado; Manfredi, Mirella; Zani, Alberto; Adorni, Roberta

    2013-02-01

    It is known that early music learning (playing of an instrument) modifies functional brain structure (both white and gray matter) and connectivity, especially callosal transfer, motor control/coordination and auditory processing. We compared visual processing of notes and words in 15 professional musicians and 15 controls by recording their synchronized bioelectrical activity (ERPs) in response to words and notes. We found that musical training in childhood (from age ~8 years) modifies neural mechanisms of word reading, whatever the genetic predisposition, which was unknown. While letter processing was strongly left-lateralized in controls, the fusiform (BA37) and inferior occipital gyri (BA18) were activated in both hemispheres in musicians for both word and music processing. The evidence that the neural mechanism of letter processing differed in musicians and controls (being absolutely bilateral in musicians) suggests that musical expertise modifies the neural mechanisms of letter reading.

  2. A common left occipito-temporal dysfunction in developmental dyslexia and acquired letter-by-letter reading?

    Directory of Open Access Journals (Sweden)

    Fabio Richlan

    Full Text Available We used fMRI to examine functional brain abnormalities of German-speaking dyslexics who suffer from slow effortful reading but not from a reading accuracy problem. Similar to acquired cases of letter-by-letter reading, the developmental cases exhibited an abnormal strong effect of length (i.e., number of letters on response time for words and pseudowords.Corresponding to lesions of left occipito-temporal (OT regions in acquired cases, we found a dysfunction of this region in our developmental cases who failed to exhibit responsiveness of left OT regions to the length of words and pseudowords. This abnormality in the left OT cortex was accompanied by absent responsiveness to increased sublexical reading demands in phonological inferior frontal gyrus (IFG regions. Interestingly, there was no abnormality in the left superior temporal cortex which--corresponding to the onological deficit explanation--is considered to be the prime locus of the reading difficulties of developmental dyslexia cases.The present functional imaging results suggest that developmental dyslexia similar to acquired letter-by-letter reading is due to a primary dysfunction of left OT regions.

  3. Closure Letter Report for Corrective Action Unit 496: Buried Rocket Site - Antelope Lake

    Energy Technology Data Exchange (ETDEWEB)

    NSTec Environmental Restoration

    2007-05-01

    A Streamlined Approach for Environmental Restoration (SAFER) Plan for investigation and closure of CAU 496, Corrective Action Site (CAS) TA-55-008-TAAL (Buried Rocket), at the Tonopah Test Range (TTR), was approved by the Nevada Department of Environmental Protection (NDEP) on July 21,2004. Approval to transfer CAS TA-55-008-TAAL from CAU 496 to CAU 4000 (No Further Action Sites) was approved by NDEP on December 21, 2005, based on the assumption that the rocket did not present any environmental concern. The approval letter included the following condition: ''NDEP understands, from the NNSA/NSO letter dated November 30,2005, that a search will be conducted for the rocket during the planned characterization of other sites at the Tonopah Test Range and, if found, the rocket will be removed as a housekeeping measure''. NDEP and U.S. Department of Energy, National Nuclear Security Administration Nevada Site Office personnel located the rocket on Mid Lake during a site visit to TTR, and a request to transfer CAS TA-55-008-TAAL from CAU 4000 back to CAU 496 was approved by NDEP on September 11,2006. CAS TA-55-008-TAAL was added to the ''Federal Facility Agreement and Consent Order'' of 1996, based on an interview with a retired TTR worker in 1993. The original interview documented that a rocket was launched from Area 9 to Antelope Lake and was never recovered due to the high frequency of rocket tests being conducted during this timeframe. The interviewee recalled the rocket being an M-55 or N-55 (the M-50 ''Honest John'' rocket was used extensively at TTR from the 1960s to early 1980s). A review of previously conducted interviews with former TTR personnel indicated that the interviewees confused information from several sites. The location of the CAU 496 rocket on Mid Lake is directly south of the TTR rocket launch facility in Area 9 and is consistent with information gathered on the lost rocket during recent

  4. On the Elements of Tragedy in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    冶静芳

    2014-01-01

    As the masterpiece of Nathaniel Hawthorn’s writing, The Scarlet Letter not only brings him fame forever, but also gives us more about people’s life in Puritan society in 17th. Since this novel is so important and excellent, the thesis mainly focus-es on probing into the theme of elements of tragedy in The Scarlet Letter. According to the whole story, the love tragedy is attrib-uted to four factors: the Puritan beliefs of original sin, the attitude of public on love outside marriage, the personalities of the main characters, and the differences between dream and reality.

  5. An Analysis of the Symbolic Colors in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    ZHU Kai-lin

    2016-01-01

    Nathaniel Hawthorn is the greatest American romantic novelist during the nineteenth century. He is skillful at the using of symbolism in his works, especially in his masterpiece The Scarlet Letter. Hawthorn is a writer with art talent, who uses differ-ent colors to enhance the artistic effects of The scarlet Letter. Colors emerging on the most occasions are used as a mayor form of symbolism to reflect the character’s feelings, personalities and fates. This paper aims to elaborate the usage of colors as a form of symbolism in three parts:the symbolic meaning of red, the symbolic meaning of black, and the symbolic meaning of grey.

  6. Resource Letter SOP-1: Self-Organizing Physics

    Science.gov (United States)

    Jacobs, Donald T.

    2015-08-01

    This Resource Letter introduces the reader to an area of physics where systems can self-organize to a particular shape or behavior that, while dynamically changing, is surprisingly robust. The self-organization is due to the complex interactions that typically preclude explanation from just the forces among adjacent molecules or objects. How one recognizes such systems and explains their behavior is the topic of this Resource Letter. Some systems exhibit universal behavior that is well documented and understood, but other systems are just now being investigated.

  7. Letters of Gold: Enabling Primitive Accumulation through Neoliberal Conservation

    OpenAIRE

    Büscher, Bram

    2009-01-01

    textabstractAbstract: In Capital I, Marx wrote that the history of the separation of the producers from the means of production “is written in the annals of mankind in letters of blood and fire” (Marx, 1976: 875). This ‘so-called primitive accumulation’, or ‘accumulation by dispossession’ in David Harvey’s words, continues unabated. Yet, its framing has changed considerably. Increasingly, capitalists have tried to avoid writing primitive accumulation in ‘letters of blood and fire’. Instead, t...

  8. Lapse resistance in the verbal letter reporting task.

    Science.gov (United States)

    Arditi, Aries

    2006-04-01

    Lapses, or misreporting errors, can affect accuracy of threshold measurements. Assumptions about lapse rate, especially in untrained observers, have consequently guided the design of at least one clinical psychophysical test. Lapse rate was assessed using a verbal letter identification paradigm like that used in visual acuity and letter contrast sensitivity testing. Subjects occasionally made slip-of-the tongue errors but spontaneously corrected them. Lapse rate (excluding such errors) was 0-3 errors per 1,536 (average rate of 0.0005). In this common clinical paradigm, in which observers set their reporting pace, and where opportunity to amend responses is available, lapse rate is negligible.

  9. Resource Letter: Research-based Assessments in Physics and Astronomy

    CERN Document Server

    Madsen, Adrian; Sayre, Eleanor C

    2016-01-01

    This resource letter provides a guide to research-based assessments (RBAs) of physics and astronomy content. These are standardized assessments that were rigorously developed and revised using student ideas and interviews, expert input, and statistical analyses. RBAs have had a major impact on physics and astronomy education reform by providing a universal and convincing measure of student understanding that instructors can use to assess and improve the effectiveness of their teaching. In this resource letter, we present an overview of all content RBAs in physics and astronomy by topic, research validation, instructional level, format, and themes, to help faculty find the best assessment for their course.

  10. Dear Hacker Letters to the Editor of 2600

    CERN Document Server

    Goldstein, Emmanuel

    2010-01-01

    Actual letters written to the leading hackers' magazine. For 25 years, 2600: The Hacker Quarterly has given voice to the hacker community in all its manifestations. This collection of letters to the magazine reveals the thoughts and viewpoints of hackers, both white and black hat, as well as hacker wannabes, technophiles, and people concerned about computer security. Insightful and entertaining, the exchanges illustrate 2600 's vast readership, from teenage rebels, anarchists, and survivalists to law enforcement, consumer advocates, and worried parents.: 2600: The Hacker Quarterly has been the

  11. 78 FR 66826 - Prior Label Approval System: Generic Label Approval

    Science.gov (United States)

    2013-11-07

    ... submitted for evaluation and approval before use under the final rule are: (1) Labels for chicken produced..., such as ``no antibiotics administered'' or ``vegetarian fed''; (4) instructional or...

  12. Effects of ocular transverse chromatic aberration on near foveal letter recognition.

    Science.gov (United States)

    Yang, Shun-nan; Tai, Yu-chi; Laukkanen, Hannu; Sheedy, James

    2009-11-01

    Transverse chromatic aberration (TCA) smears retinal images of peripheral stimuli. In reading, text information is extracted from both foveal and near fovea, where TCA magnitude is relatively small and variable. The present study investigated whether TCA significantly affects near foveal letter identification. Subjects were briefly presented a string of five letters centered one degree of visual angle to the left or right of fixation. They indicated whether the middle letter was the same as a comparison letter subsequently presented. Letter strings were rendered with a reddish fringe on the left edge of each letter and a bluish fringe on the right edge, consistent with expected left periphery TCA, or with the opposite fringe consistent with expected right periphery TCA. Effect of the color fringing on letter recognition was measured by comparing the response accuracy for fringed and non-fringed stimuli. Effects of lateral interference were examined by manipulating inter-letter spacing and similarity of neighboring letters. Results demonstrated significantly improved response accuracy with the color fringe opposite to the expected TCA, but decreased accuracy when consistent with it. Narrower letter spacing exacerbated the effect of the color fringe, whereas letter similarity did not. Our results suggest that TCA significantly reduces the ability to recognize letters in the near fovea by impeding recognition of individual letters and by enhancing lateral interference between letters.

  13. Visual and Artistic Functions of Letters Khaghani’s Poetry

    Directory of Open Access Journals (Sweden)

    Dr. M. Zolfaghari

    Full Text Available The intensity of emotion and vibration of meaning in the poet's mind causes him to go beyond the ordinary language and through metaphors, similes and linguistic preparation he conveys intellectual and emotional meanings. He has a sharp eye and a sensitive spirit and creative temprement and by inventing new images shows the creativity and imagination in various arenas and attempts in the way of literary strength and creating personal style and this point more than anything else must be done by presenting images and newness. Perhaps in the sixth century, and especially in Azerbaijani school, more than other periods, poets have been looking for creating innovative style in eloquence. Their major attempts were mainly in imaging, it was a wide field that they have competed and it is natural that in this illustration the alphabet letters would be very helpful. Khaghani poetry as one of the greatest poets of this school has the perfect poetrical book of painting and meaning, and delicated pattern in new and different scientific, cultural and religious paintings and letters are a broad range of elements that put a new field in front of the poet and he is aware of the potential features of the letters and also the new images and the artistic creativity.This paper shows descriptive - analytical study of various aspects of Khaghani’s poetry and frequency of letters in the alphabet, authentic images based on alphabet, taken at different pseudo relevance of poetry in the context of multiple semantic and literal characters, making figures of speech based on literary characters, images and characters and the sense of connection . . . which has been shown in his poetry.Letter has double and even multiple uses in Khaghani poetic works (divan and more than the construction of words which is the real and common sense that is used as an artistic. There is a world in the heart of every letter, word and morpheme lies in the poet's point of view is the last and

  14. How do we code the letters of a word when we have to write it? Investigating double letter representation in French.

    Science.gov (United States)

    Kandel, Sonia; Peereman, Ronald; Ghimenton, Anna

    2014-05-01

    How do we code the letters of a word when we have to write it? We examined whether the orthographic representations that the writing system activates have a specific coding for letters when these are doubled in a word. French participants wrote words on a digitizer. The word pairs shared the initial letters and differed on the presence of a double letter (e.g., LISSER/LISTER). The results on latencies, letter and inter-letter interval durations revealed that L and I are slower to write when followed by a doublet (SS) than when not (ST). Doublet processing constitutes a supplementary cognitive load that delays word production. This suggests that word representations code letter identity and quantity separately. The data also revealed that the central processes that are involved in spelling representation cascade into the peripheral processes that regulate movement execution.

  15. Obinutuzumab: first global approval.

    Science.gov (United States)

    Cameron, Fiona; McCormack, Paul L

    2014-01-01

    Obinutuzumab (Gazyva™) is an intravenously administered, humanized and glycoengineered, type II anti-CD20 monoclonal antibody for the treatment of B-cell malignancies. It is approved in the US for use in combination with chlorambucil for the first-line treatment of chronic lymphocytic leukaemia (CLL), and has been filed for approval in the EU in this indication. The antibody is based on GlycArt Biotechnology's (later Roche Glycart AG) proprietary GlycoMAb® technology, which uses glycoengineered antibodies that specifically increase antibody-dependent cellular cytotoxicity and thereby increase immune-mediated target cell death. Obinutuzumab is a type II anti-CD20 antibody that induces enhanced direct cell death. The monoclonal antibody is in worldwide phase III development with Roche and its subsidiaries, Genentech and Chugai Pharmaceutical, as well as Biogen Idec, for diffuse large B-cell lymphoma and non-Hodgkin's lymphoma generally, and is also in phase III development in countries outside of the US and EU for CLL.

  16. Safinamide: first global approval.

    Science.gov (United States)

    Deeks, Emma D

    2015-04-01

    Safinamide (Xadago(®)) is an oral α-aminoamide derivative developed by Newron for the treatment of Parkinson's disease (PD). The drug has both dopaminergic properties (highly selective and reversible inhibition of monoamine oxidase-B) and non-dopaminergic properties (selective sodium channel blockade and calcium channel modulation, with consequent inhibition of excessive glutamate release). Safinamide is approved in the EU, Iceland, Lichtenstein and Norway, as an add-on therapy to stable-dose levodopa, alone or in combination with other PD therapies in mid- to late-stage fluctuating PD patients; regulatory submissions have also been filed in the USA and Switzerland for its use in this indication. Additional submissions have been made in the USA, Iceland, Lichtenstein, Norway and Switzerland for early-stage PD. Safinamide has also undergone phase II investigation in PD patients with drug-induced dyskinesia (France, Germany, Austria, Canada and South Africa) or cognitive impairment (USA and Spain). This article summarizes the milestones in the development of safinamide leading to its first approval for PD.

  17. From word superiority to word inferiority: Visual processing of letters and words in pure alexia

    DEFF Research Database (Denmark)

    Habekost, Thomas; Petersen, Anders; Behrmann, Marlene

    2014-01-01

    tasks for all patients, and this pattern was more pronounced in the more severely affected patients. The relationship between performance with single letters and words was, however, not straightforward: One patient performed within the normal range on the letter perception task, while being severely...... impaired in letter naming and word processing, and performance with letters and words was dissociated in all four patients, with word reading being more severely impaired than letter recognition. This suggests that the word reading deficit in pure alexia may not be reduced to an impairment in single letter...

  18. A Mentoring Opportunity: A Joint Effort in Writing Letters of Recommendation.

    Science.gov (United States)

    Master, Zubin

    2017-01-01

    Integrity in writing letters of recommendation is important to academic research because it is an influential criterion used pervasively in peer review. While research in the integrity of recommendation letters has concentrated on contents of the letter, bias, and reliability, few have questioned the process of letter writing. Here, I argue that letter writing should be a joint opportunity between mentor/supervisor/advisor and trainee. It results in more compelling letters, may prevent errors and the use of biased language, and serves as an excellent mentoring opportunity promoting self-reflection.

  19. Drugs Approved for Cervical Cancer

    Science.gov (United States)

    ... Human Papillomavirus (HPV) Nonavalent Vaccine Recombinant Human Papillomavirus (HPV) Quadrivalent Vaccine Drugs Approved to Treat Cervical Cancer Avastin (Bevacizumab) Bevacizumab Blenoxane (Bleomycin) Bleomycin Hycamtin (Topotecan ...

  20. Friday Letters: Connecting Students, Teachers, and Families through Writing

    Science.gov (United States)

    Newman, Terry H.; Bizzarri, Sarah A.

    2012-01-01

    An important part of student success in school is the involvement of families. However, the communication between students and families regarding school is often sparse at best and caregivers can feel left out as to what is happening. Friday letters improve communication between students and families and also provide a myriad of instructional…

  1. Grooming the Victim: An Analysis of a Perpetrator's Seduction Letter.

    Science.gov (United States)

    Singer, Mark I.; And Others

    1992-01-01

    This paper reviews the literature on the sexual victimization of adolescent males, with emphasis on victim selection factors and strategies. A letter written by a middle-aged man to entice a teenage boy into sexual activity is then presented and analyzed. (DB)

  2. Letters from a suicide: Van Gogh and his sister.

    Science.gov (United States)

    Lester, David

    2010-04-01

    An analysis of trends over a 3-yr. period in the letters of Vincent Van Gogh to his sister as the time of his suicide approached identified 8 trends, including an increase in words concerned with anxiety and words concerned with the past.

  3. Letters of Gold: Enabling Primitive Accumulation through Neoliberal Conservation

    NARCIS (Netherlands)

    B.E. Büscher (Bram)

    2009-01-01

    textabstractAbstract: In Capital I, Marx wrote that the history of the separation of the producers from the means of production “is written in the annals of mankind in letters of blood and fire” (Marx, 1976: 875). This ‘so-called primitive accumulation’, or ‘accumulation by dispossession’ in David H

  4. A Genre-based Analysis of English Refusal Letters

    Institute of Scientific and Technical Information of China (English)

    费伟

    2014-01-01

    The present study analyzes ten English refusal letters of two subcategories based on Swales ’genre analysis model and finds that difference exists in the generic features of the two subcategorized types. Teachers should reveal the underlying rationale behind linguistic features of a specific genre so that students can not only identify genre but also apply it appropriately.

  5. Resource Letter FNP-1: Frontiers of nuclear physics

    Science.gov (United States)

    Bertsch, G. F.

    2004-08-01

    This Resource Letter provides a bibliography of the current research activities in nuclear physics and also a guide for finding useful nuclear data. The major areas included are nuclear structure and reactions, symmetry tests, nuclear astrophysics, nuclear theory, high-density matter, and nuclear instrumentation.

  6. Model business letters, emails and other business documents

    CERN Document Server

    Taylor, Shirley

    2012-01-01

    For anyone who wants to communicate effectively in business, this is your complete reference guide for any form of written communication. Packed with over 500 sample documents, over 100 tips for better business writing and useful templates you can apply to your writing immediately, Model Business Letters will help you put the key rules of good business writing into action.

  7. Underlying Cause(s) of Letter Perseveration Errors

    Science.gov (United States)

    Fischer-Baum, Simon; Rapp, Brenda

    2012-01-01

    Perseverations, the inappropriate intrusion of elements from a previous response into a current response, are commonly observed in individuals with acquired deficits. This study specifically investigates the contribution of failure-to activate and failure-to-inhibit deficit(s) in the generation of letter perseveration errors in acquired…

  8. 33 CFR 401.68 - Explosives Permission Letter.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 3 2010-07-01 2010-07-01 false Explosives Permission Letter. 401.68 Section 401.68 Navigation and Navigable Waters SAINT LAWRENCE SEAWAY DEVELOPMENT CORPORATION, DEPARTMENT OF TRANSPORTATION SEAWAY REGULATIONS AND RULES Regulations Dangerous Cargo § 401.68...

  9. A Cohesive and Coherent Analysis of The Purloined Letter

    Institute of Scientific and Technical Information of China (English)

    杜娟娟; 郭鸿雁

    2013-01-01

      The thesis aims to do a research on the cohesion and coherence in The Purloined Letter written by Edgar Allan Poe based on the theories of Halliday and Hasan as well as the Chinese scholars Zhang Delu and Liu Rushan. By the means of them, Poe’s ingenious composition and vivid characters emerge in the mind of the readers.

  10. Word-initial letters influence fixation durations during fluent reading

    Directory of Open Access Journals (Sweden)

    Christopher J. Hand

    2012-04-01

    Full Text Available The present study examined how word-initial letters influence lexical access during reading. Eye movements were monitored as participants read sentences containing target words. Three factors were independently manipulated. First, target words had either high or low constraining word-initial letter sequences (e.g., dwarf or clown, respectively. Second, targets were either high or low in frequency of occurrence (e.g., train or stain, respectively. Third, targets were embedded in either biasing or neutral contexts (i.e., targets were high or low in their predictability. This 2 (constraint × 2 (frequency × 2 (context design allowed us to examine the conditions under which a word’s initial letter sequence could facilitate processing. Analyses of fixation duration data revealed significant main effects of constraint, frequency, and context. Moreover, in measures taken to reflect early lexical processing (i.e., first and single fixation duration, there was a significant interaction between constraint and context. The overall pattern of findings suggests lexical access is facilitated by highly constraining word-initial letters. Results are discussed in comparison to recent studies of lexical features involved in word recognition during reading.

  11. The letter of submission: avoiding the promotional genre

    DEFF Research Database (Denmark)

    Shaw, Philip; Okamura, Akiko

    1998-01-01

    Functionally the letter of submission accompanying an article submitted to a journal is promotional, but it does not have the form one would expect from e.g. Bhatia 1993. Instead it is extremely brief and uninformative. This reflects the so-called Utilitarian Discourse which is a shared feature...

  12. Relations among Early Object Recognition Skills: Objects and Letters

    Science.gov (United States)

    Augustine, Elaine; Jones, Susan S.; Smith, Linda B.; Longfield, Erica

    2015-01-01

    Human visual object recognition is multifaceted and comprised of several domains of expertise. Developmental relations between young children's letter recognition and their 3-dimensional object recognition abilities are implicated on several grounds but have received little research attention. Here, we ask how preschoolers' success in recognizing…

  13. 26 CFR 601.201 - Rulings and determinations letters.

    Science.gov (United States)

    2010-04-01

    ... not merely incorporated by reference, and must be accompanied by an analysis of their bearing on the... requirements for establishing that translations of foreign law are satisfactory as evidence for purposes of... taxpayer believes that a determination letter of this type is in error, he may ask the district director...

  14. The Psychological Reflection of Hawthorn in the Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    SHI Yan-qing

    2015-01-01

    The Scarlet Letter is Nathaniel Hawthorne’s masterpiece, representing the height of Hawthorne’s literary genius. This thesis tries to reveal part of the author’s psychological activities, repressed feelings from his childhood from analyzing the main characters, especially Hester, the mother and Pearl, the daughter.

  15. 33 CFR 157.204 - Letter of acceptance.

    Science.gov (United States)

    2010-07-01

    ...) POLLUTION RULES FOR THE PROTECTION OF THE MARINE ENVIRONMENT RELATING TO TANK VESSELS CARRYING OIL IN BULK Dedicated Clean Ballast Tanks on Tank Vessels General § 157.204 Letter of acceptance. The Coast Guard... submitted under § 157.202 show that the dedicated clean ballast tank system meets this subpart....

  16. Just keep it simple : a field experiment on fundraising letters

    NARCIS (Netherlands)

    Bekkers, René; Crutzen, Olaf

    2007-01-01

    This paper studies how the use of a colour picture in fundraising letters affect response rates and the amount donated in a fundraising campaign. Envelopes, with a full colour picture were tested against envelopes, without a picture in a controlled field experiment at a national religious charity in

  17. CNPC Signed New Contracts and Letters with ESSO Corp

    Institute of Scientific and Technical Information of China (English)

    Lin Rujin; Li Qing

    1995-01-01

    @@ On April 7, 1995 two petroleum contracts, concerning the deep horizons in the northwest of Songliao Basin and Dafenshan-Eboliang Block in Qaidam Basin and two letters of intent for petroleum cooperation were signed in Beijing by Zhuo Yongkang,Vice President , CNPC and Jon L.Thompson, President, Esso Exploration Company.

  18. Cold-induced vasodilation : letter to the editor

    NARCIS (Netherlands)

    Daanen, H.A.M.

    2009-01-01

    Reactie op: Flouris, et al. Effect of body temperature on cold induced vasodilationa. Eur J Applied Phys 2008;104:491-499. De aurteurs hebben daar weer een reply op geschreven; Flouris AD, Cheung SS (2009) Authors’ response to H. Daanen’s ‘cold-induced vasodilation’ letter. Eur J Appl Physiol 106:31

  19. SPS Research into superconductivity highlighted in Physical Review Letters

    OpenAIRE

    2016-01-01

    Research conducted by Dr Jorge Quintanilla as part of an international collaboration has been chosen as an Editors' Suggestion on the Physical Review Letters website. The full article can be accessed here. Below is a summary from Dr Quintanilla about what the research was and how it is useful.

  20. Functional communication within a perceptual network processing letters and pseudoletters.

    Science.gov (United States)

    Herdman, Anthony T

    2011-10-01

    Many studies have identified regions within human ventral visual stream to be important for object identification and categorization; however, knowledge of how perceptual information is communicated within the visual network is still limited. Current theories posit that if a high correspondence between incoming sensory information and internal representations exists, then the object is rapidly identified, and if there is not, then the object requires extra detailed processing. Event-related responses from the present magnetoencephalography study showed two main effects. The N1m peak latencies were approximately 15 milliseconds earlier to familiar letters than to unfamiliar pseudoletters, and the N2m was more negative to pseudoletters than to letters. Event-related beamforming analyses identified these effects to be within bilateral visual cortices with a right lateralization for the N2m effect. Furthermore, functional connectivity analyses revealed that gamma-band (50-80 Hz) oscillatory phase synchronizations among occipital regions were greater to letters than to pseudoletters (around 85 milliseconds). However, during a later time interval between 245 and 375 milliseconds, pseudoletters elicited greater gamma-band phase synchronizations among a more distributed occipital network than did letters. These findings indicate that familiar object processing begins by at least 85 milliseconds, which could represent an initial match to an internal template. In addition, unfamiliar object processing persisted longer than that for familiar objects, which could reflect greater attention to inexperienced objects to determine their identity and/or to consolidate a new template to aid in future identification.

  1. RL-PER1: Resource Letter on Physics Education Research.

    Science.gov (United States)

    McDermott, Lillian C.; Redish, Edward F.

    The purpose of this resource letter is to provide an overview of research on the learning and teaching of physics. The references have been selected to meet the needs of two groups of physicists engaged in physics education. The first is the growing number whose field of scholarly inquiry is (or might become) physics education research. The second…

  2. Resource Letter PhD-1: Physics Demonstrations.

    Science.gov (United States)

    Davis, John A.; Eaton, Bruce G.

    1979-01-01

    This resource letter is an annotated bibliography aimed at individuals who have recently become interested in lecture demonstrations in physics. Listed are 103 printed sources of information on lecture demonstrations. Whenever possible, annotations are followed by reviews so that other opinions can be consulted. (BT)

  3. Letters Home as an Alternative to Lab Reports

    Science.gov (United States)

    Lane, W. Brian

    2014-01-01

    The traditional lab report is known to create several pedagogical shortcomings in the introductory physics course, particularly with regard to promoting student engagement and encouraging quality writing. This paper discusses the use of a "letter home" written to a non-physicist as an alternative to lab reports that creates a more…

  4. Resource Letter TPB-1: Theoretical Physics and Biology

    Science.gov (United States)

    MacDonald, N.

    1974-01-01

    This is one of a series of Resource Letters on different topics, intended to guide college physicists to some of the literature and other teaching aids. This bibliography is designed to help physicists identify literature related to mathematical biology. (Author/RH)

  5. Authors' response to the letter from Kalleian Eserian et al

    NARCIS (Netherlands)

    Riet-Nales, D.A. van; Doeve, M.E.; Nicia, A.E.; Teerenstra, S.; Notenboom, K.; Hekster, Y.A.; Bemt, B.J.F van den

    2015-01-01

    This letter is a response to the comments of Kalleian Eserian et al. on our study relating to the accuracy, precision and sustainability of six tablet splitters and a kitchen knife as an alternative to breaking paracetamol 500mg tablets by hand. We would like to inform the readers of International J

  6. Research on the Attitude towards Lettered-words in Chinese

    Institute of Scientific and Technical Information of China (English)

    潘正华

    2014-01-01

    Lettered words have sprouted in all kinds of situations and many kinds of media, which has been a very common phenomenon. This essay focuses on the relationship between the attitudes and the factors such as age, sex, and the educational background, trying to find some correlation between them, which is important also in the language policy.

  7. The Effects of Sin in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    吴希博; 逯海涛

    2008-01-01

    "Sin" plays a very important role in the understanding of Hawthorne's "psychological romance"- The Scarlet Letter. The paper introduces the major view that influences him--the Puritan doctrine of "original sin" so as to investigate Hawthorne's own attitudes towards the sin and the effects of sin on the two main characters in the novel.

  8. "Letter-Space": Typographic Translations of Urban Place

    Science.gov (United States)

    Naismith, Jacqueline; O'Sullivan, Annette

    2011-01-01

    This article discusses a Bachelor of Design honours year typography project in the medium of letterpress. The "Letter-space" project positioned letterpress as a textual, spatial and structural visual language, through which the experiences and meanings of a local urban place were translated, mapped and given form through typographic design. We…

  9. Documentary Letters of Credit, Legal Nature and Sources of Law

    Directory of Open Access Journals (Sweden)

    Alavi Hamed

    2016-06-01

    Full Text Available There is no doubt about risky nature of international trade. Such risk can be conceptualized as country risk, transportation risk, customer risk and etc. Documentary Letters of Credit (LC are used as a method of payment in international business for many centuries in order to reduce risk of trade specially when parties are located in different countries and do not have precise information from financial standing of each other. In such occasion LC will reduce the risk of trade by shifting payment obligation from buyer as an individual to a payment guarantee of a bank as a legal entity in return for presentation of complying documents with terms of credit by seller. Familiarity with legal nature and different legal frameworks which govern the international operation of documentary letters of credit can facilitate the process of international trade for businessmen and boost national economies. However, lack of knowledge about them can impose huge losses on international traders. Situation will be more complicated when we understand that there are many internationally recognized legal frameworks which can affect the operation of LC and they get frequently updated in order to address technological and economic developments in global market. In this paper, author tries to answer questions regarding (i what are international legal frameworks governing operation of documentary letters of credit? (ii which areas of LC operation has been covered by them and (iii how do they address the legal questions regarding international operation of documentary letters of credit?

  10. Tactile Perception and Braille Letter Recognition: Effects of Developmental Teaching.

    Science.gov (United States)

    Mangold, Sally S.

    1978-01-01

    The extent to which a developmental program of tactile perception and braille letter recognition would affect errors in these abilities and reduce scrubbing and backtracking behaviors of 30 legally blind braille users (5-15 years old) was studied. (Author/BD)

  11. Transposed-Letter Priming across Inflectional Morpheme Boundaries

    Science.gov (United States)

    Zargar, Ehsan Shafiee; Witzel, Naoko

    2017-01-01

    This study reports findings from two experiments testing whether a transposed-letter (TL) priming effect can be obtained when the transposition occurs across morphological boundaries. Previous studies have primarily tested derivationally complex words or compound words, but have not examined a more rule-based and productive morphological…

  12. Discourse Strategies of Italian and English Sales Promotion Letters

    Science.gov (United States)

    Vergaro, Carla

    2004-01-01

    This article describes a contrastive study on rhetorical differences between Italian and English sales promotion letters. It is assumed that cultural differences affect discourse genres traditionally considered as standardized, ritual or even formulaic, written business communication being a case in point. It was our goal to investigate how…

  13. Color associations for days and letters across different languages

    NARCIS (Netherlands)

    Rouw, R.; Case, L.; Gosavi, R.; Ramachandran, V.

    2014-01-01

    While colors are commonplace in everyday metaphors, relatively little is known about implicit color associations to linguistic or semantic concepts in a general population. In this study, we test color associations for ordered linguistic concepts (letters and days). The culture and language specific

  14. 谈谈字母词%Talk about letter words

    Institute of Scientific and Technical Information of China (English)

    胡月

    2013-01-01

    随着现代社会的发展和中外交流的加强,字母词作为一种新型词语为人们广泛使用。本文讨论了字母词的概念及五种分类,字母词由于对外开放、与国际接轨、日常交际和语用心理影响而流行,并且对字母词具有结构简单及形象直观,含蓄委婉和轻松幽默的表达功效进行概括性分析,让人们正视字母词的使用从而引导语言的健康发展。%With the quick development of the modern society and the enhanced communication between China and abroad, letter words as newly developed, has been widely adopted by people. This paper will discuss the definition and five categories of letter words, explaining such factors leading to the popularity of letter words as the characteristics of open quality and daily dialogue, conforming with the international use, and the influence of pragmatic psychological. Also, the paper will summarize the expression efficiency of letter words including the simple construction and visual pattern, implicit, lively and humorous properties, which make people have a better understanding of the letter words and guide the healthy development of the language.

  15. Substituted-Letter and Transposed-Letter Effects in a Masked Priming Paradigm with French Developing Readers and Dyslexics

    Science.gov (United States)

    Lete, Bernard; Fayol, Michel

    2013-01-01

    The aim of the study was to undertake a behavioral investigation of the development of automatic orthographic processing during reading acquisition in French. Following Castles and colleagues' 2007 study ("Journal of Experimental Child Psychology, 97," 165-182) and their lexical tuning hypothesis framework, substituted-letter and…

  16. FDA-Approved HIV Medicines

    Science.gov (United States)

    HIV Treatment FDA-Approved HIV Medicines (Last updated 2/27/2017; last reviewed 2/27/2017) Treatment with HIV medicines is ... approved by the U.S. Food and Drug Administration (FDA) for the treatment of HIV infection in the ...

  17. An audit of letters of referral to a prosthodontic department in a dental teaching hospital.

    Science.gov (United States)

    Fenlon, Michael R; Glick, Shiri; Sherriff, Martyn

    2008-09-01

    The purpose of this study was to investigate the quality and number of letters of referral for new patients received in the Prosthodontics Department of a Dental Teaching Hospital. Letters received during the month of May 2006 were included. Each letter of referral was tested against five criteria which might be expected in an appropriate letter of referral. These were information on the following: relevant dental history, relevant medical history, teeth present, diagnosis, and treatment plan. The results showed that only 8% of letters met all five criteria and 11% met none of them. Letters requesting better information were sent to referring practitioner as a result of this audit. However a re-audit in May 2007 showed that 9% of letters met all five criteria and 15% met none of them. A need has been identifiedfor better referral letters and ways of achieving this were discussed.

  18. Letter about Ivory-billed Woodpecker on Allan Grey Estate (Dahomey NWR)

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Letter contains historic information regarding ivory-billed woodpecker occurance on Dahomey NWR prior to World War II. Letter found in museum in PA by Dr. Jerome...

  19. Retinal Locus and the Identification of Tachistoscopically Presented Letters by Retarded and Nonretarded Individuals

    Science.gov (United States)

    Mosley, James L.

    1978-01-01

    Two-letter stimulus displays, differing in the magnitude of the horizontal spatial separation between the letters, were presented tachistoscopically to 10 retarded and 1 nonretarded adults. (Author/CL)

  20. Teaching letter sounds to kindergarten English language learners using incremental rehearsal.

    Science.gov (United States)

    Peterson, Meredith; Brandes, Dana; Kunkel, Amy; Wilson, Jennifer; Rahn, Naomi L; Egan, Andrea; McComas, Jennifer

    2014-02-01

    Proficiency in letter-sound correspondence is important for decoding connected text. This study examined the effects of an evidence-based intervention, incremental rehearsal (IR), on the letter-sound expression of three kindergarten English language learners (ELLs) performing below the district benchmark for letter-sound fluency. Participants were native speakers of Hmong, Spanish, and Polish. A multiple-baseline design across sets of unknown letter sounds was used to evaluate the effects of IR on letter-sound expression. Visual analysis of the data showed an increase in level and trend when IR was introduced in each phase. Percentage of all non-overlapping data (PAND) ranged from 95% to 100%. All participants exceeded expected growth and reached the spring district benchmark for letter-sound fluency. Results suggest that IR is a promising intervention for increasing letter-sound expression for ELLs who evidence delays in acquiring letter sounds.

  1. Electronic Approval of Invoices (AEF)

    CERN Multimedia

    2004-01-01

    With a view to the simplification of administrative procedures, AS and FI Departments have completed the second phase of the new procedure for the electronic approval of invoices via the EDH application. The aim of this new procedure is to rationalise the invoice approval process, notably by eliminating paper copies from the approval circuit. This will simplify the processing of invoices and facilitate their timely settlement, while at the same time maintaining a high level of security. Phase II includes handling the electronic approval process of invoices whose amounts do not correspond exactly to those of the associated orders. In such cases, budgetary approval is required for the entire invoiced amount. Further information can be obtained at : http://ais.cern.ch/projs/AEF/help/F_help.htm Phase II of the procedure will be introduced gradually with effect from April 2004. Finance Department, Accounts Payable Section Tel: 72295 Organisation and Procedures Tel: 75885 Information Technologies Department,...

  2. Higher-contrast requirements for recognizing low-pass-filtered letters.

    Science.gov (United States)

    Kwon, MiYoung; Legge, Gordon E

    2013-01-09

    Kwon and Legge (2011) found that high levels of letter recognition accuracy are possible even when letters are severely low-pass filtered (0.9 cycles per letter). How is letter recognition possible with such severe reduction in the spatial resolution of stimulus letters? Clues may come from understanding the possible interaction between contrast and spatial resolution in letter recognition. Here, we asked what the effect is on the contrast threshold for detecting and recognizing letters as the spatial-frequency cutoff of letters is reduced (in cycles per letter). We measured contrast thresholds of seven normally sighted subjects for detecting and recognizing single letters of the English alphabet. The letters were low-pass filtered with several cutoff frequencies (0.9-3.5 cycles per letter, including unfiltered letters). We found that differences in contrast thresholds between detection and recognition increased substantially with decreasing cutoff frequency. We also incorporated the human contrast sensitivity function into an ideal observer model and found qualitatively good agreement between the pattern of performance for the model and our human subjects. Our findings show that the human visual system requires higher contrast for letter recognition when spatial resolution is severely limited. Good agreement between the model and human subjects shows that the greater contrast requirement for recognizing low-pass letters is due to a reduction in the information content of the letters rather than a change in human visual processing. The reduction in stimulus information may be due to increasing stimulus similarity associated with a reduction in spatial-frequency cutoff.

  3. Latin Classics in the Letters of Saint Jerome

    Directory of Open Access Journals (Sweden)

    Julijana Visočnik

    2002-12-01

    Full Text Available Saint Jerome, one of the most important Latin Fathers of the Church, was born in the 4th century AD in the town of Stridon, located somewhere on the border between Pannonia and Dalmatia. After finishing elementary school in his home town, he continued his education in Rome with the well-known teacher and grammarian Aelius Donatus, becoming acquainted with all the important Latin classics. In Rome, Jerome was baptised and after that he decided to become a monk. He dedicated his life to God and started writing prayers, translating the Bible and correcting its existing translations, and engaging in criticisms and polemics caused by contemporary events and practices. He also wrote over 120 letters, which were addressed to various people, some of them famous in their own right and some known today precisely through his writings. A lot of variety can be found in his letters: some of them are just short answers, while others grew to be independent books including discussions about moral, exegetic, and dogmatic questions. Letter XXII was written in the year 384 AD as an instruction for the virgin life of Julia Eustochium. In chapter 30, the reader is introduced to some facts about Jerome's life, as well as to the statement: "Ciceronianus es, non Christianus." This he heard in his feverish dreams, nightmares even, in which he was told not to read pagan literature any more. He promised not to, but the question inevitably arises if this was possible. He had already read and learnt by heart so many Latin classics that it was impossible for him to ignore them. Therefore it comes as no surprise that his writings are permeated with echoes of, or borrowings from, Horace, Virgil, Terence, Cicero, Plautus, Lucretius, Persius, Ovid, Martial, Quintilian, and Seneca. His letters also preserve a number of passages from their works. The Latin authors most frequently mentioned in the letters are Virgil, Horace, and Cicero - writers whose works were used as examples in

  4. 42 CFR 84.50 - Types of respirators to be approved; scope of approval.

    Science.gov (United States)

    2010-10-01

    ... 42 Public Health 1 2010-10-01 2010-10-01 false Types of respirators to be approved; scope of... Classification of Approved Respirators; Scope of Approval; Atmospheric Hazards; Service Time § 84.50 Types of respirators to be approved; scope of approval. Approvals shall be issued for the types of respirators...

  5. The A.I.D.A. Plan and the Writing of Sales Letters.

    Science.gov (United States)

    Jong, Rowena

    A study based on textual analysis of sales letters is reported that evaluates the Attention, Interest, Desire, and Action (AIDA) approach to teaching the writing of sales letters. Thirty business letters written by undergraduate business students and executives were analyzed. The forms of cohesion, voice pattern, and information focus of the…

  6. Developmental Changes during Childhood in Single-Letter Acuity and Its Crowding by Surrounding Contours

    Science.gov (United States)

    Jeon, Seong Taek; Hamid, Joshua; Maurer, Daphne; Lewis, Terri L.

    2010-01-01

    Crowding refers to impaired target recognition caused by surrounding contours. We investigated the development of crowding in central vision by comparing single-letter and crowding thresholds in groups of 5-year-olds, 8-year-olds, 11-year-olds, and adults. The task was to discriminate the orientation of a Sloan letter E. Single-letter thresholds,…

  7. Experience-dependent hemispheric specialization of letters and numbers is revealed in early visual processing.

    Science.gov (United States)

    Park, Joonkoo; Chiang, Crystal; Brannon, Elizabeth M; Woldorff, Marty G

    2014-10-01

    Recent fMRI research has demonstrated that letters and numbers are preferentially processed in distinct regions and hemispheres in the visual cortex. In particular, the left visual cortex preferentially processes letters compared with numbers, whereas the right visual cortex preferentially processes numbers compared with letters. Because letters and numbers are cultural inventions and are otherwise physically arbitrary, such a double dissociation is strong evidence for experiential effects on neural architecture. Here, we use the high temporal resolution of ERPs to investigate the temporal dynamics of the neural dissociation between letters and numbers. We show that the divergence between ERP traces to letters and numbers emerges very early in processing. Letters evoked greater N1 waves (latencies 140-170 msec) than did numbers over left occipital channels, whereas numbers evoked greater N1s than letters over the right, suggesting letters and numbers are preferentially processed in opposite hemispheres early in visual encoding. Moreover, strings of letters, but not single letters, elicited greater P2 ERP waves (starting around 250 msec) than numbers did over the left hemisphere, suggesting that the visual cortex is tuned to selectively process combinations of letters, but not numbers, further along in the visual processing stream. Additionally, the processing of both of these culturally defined stimulus types differentiated from similar but unfamiliar visual stimulus forms (false fonts) even earlier in the processing stream (the P1 at 100 msec). These findings imply major cortical specialization processes within the visual system driven by experience with reading and mathematics.

  8. Epistolary and Emotional Education: The Letters of an Irish Father to His Daughter, 1747-1752

    Science.gov (United States)

    Ruberg, Willemijn

    2008-01-01

    The letters Bishop Edward Synge (1691-1762) wrote to his daughter Alicia (1733-1807) in 1747-1752 are discussed to show how correspondence from a father to a daughter could be used to teach a teenage girl how to spell and write letters. Moreover, these letters are an excellent source to show how emotional behaviour was taught. Instructions on…

  9. I'm Gonna Sit Right Down and Write Someone a Letter. [Lesson Plan].

    Science.gov (United States)

    National Endowment for the Humanities (NFAH), Washington, DC.

    This lesson plan uses fascinating letters (written by people famous, infamous, and ordinary, some of whom lived through extraordinary times), as a starting point for discussion of and practice in the conventions and purposes of letter-writing. Its 10 lessons seek to make students able to: (1) list at least 5 conventions of letter writing; (2) cite…

  10. Learning of Letter Names Follows Similar Principles across Languages: Evidence from Hebrew

    Science.gov (United States)

    Treiman, Rebecca; Levin, Iris; Kessler, Brett

    2007-01-01

    Letter names play an important role in early literacy. Previous studies of letter name learning have examined the Latin alphabet. The current study tested learners of Hebrew, comparing their patterns of performance and types of errors with those of English learners. We analyzed letter-naming data from 645 Israeli children who had not begun formal…

  11. 78 FR 73450 - Defense Federal Acquisition Regulation Supplement: Preparation of Letter of Offer and Acceptance...

    Science.gov (United States)

    2013-12-06

    ... Regulation Supplement: Preparation of Letter of Offer and Acceptance (DFARS Case 2012-D048) AGENCY: Defense... of ] the letter of offer and acceptance for a foreign military sales program that will require an... activity in preparing the letter of offer and acceptance for a foreign military sales program that...

  12. 78 FR 28793 - Defense Federal Acquisition Regulation Supplement: Preparation of Letter of Offer and Acceptance...

    Science.gov (United States)

    2013-05-16

    ... Regulation Supplement: Preparation of Letter of Offer and Acceptance (DFARS Case 2012-D048) AGENCY: Defense... officer role in assisting the DoD implementing agency in preparation of the letter of offer and acceptance... to assist the DoD implementing activity in preparing the letter of offer and acceptance for a...

  13. 46 CFR 308.522 - Collateral deposit fund, letter of transmittal, Form MA-302.

    Science.gov (United States)

    2010-10-01

    ... 46 Shipping 8 2010-10-01 2010-10-01 false Collateral deposit fund, letter of transmittal, Form MA-302. 308.522 Section 308.522 Shipping MARITIME ADMINISTRATION, DEPARTMENT OF TRANSPORTATION EMERGENCY... Collateral deposit fund, letter of transmittal, Form MA-302. The standard form of letter of transmittal...

  14. Drugs Approved for Stomach (Gastric) Cancer

    Science.gov (United States)

    ... about Your Treatment Research Drugs Approved for Stomach (Gastric) Cancer This page lists cancer drugs approved by the ... are not listed here. Drugs Approved for Stomach (Gastric) Cancer Cyramza (Ramucirumab) Docetaxel Doxorubicin Hydrochloride 5-FU (Fluorouracil ...

  15. Letter case and text legibility in normal and low vision.

    Science.gov (United States)

    Arditi, Aries; Cho, Jianna

    2007-09-01

    It is thought by cognitive scientists and typographers alike, that lower-case text is more legible than upper-case. Yet lower-case letters are, on average, smaller in height and width than upper-case characters, which suggests an upper-case advantage. Using a single unaltered font and all upper-, all lower-, and mixed-case text, we assessed size thresholds for words and random strings, and reading speeds for text with normal and visually impaired participants. Lower-case thresholds were roughly 0.1 log unit higher than upper. Reading speeds were higher for upper- than for mixed-case text at sizes twice acuity size; at larger sizes, the upper-case advantage disappeared. Results suggest that upper-case is more legible than the other case styles, especially for visually-impaired readers, because smaller letter sizes can be used than with the other case styles, with no diminution of legibility.

  16. Martyrs' last letters: are they the same as suicide notes?

    Science.gov (United States)

    Leenaars, Antoon A; Ben Park, B C; Collins, Peter I; Wenckstern, Susanne; Leenaars, Lindsey

    2010-05-01

    Of the 800,000 suicides worldwide every year, a small number fall under Emile Durkheim's term of altruistic suicides. Study on martyrdom has been limited. There has to date, for example, been no systematic empirical study of martyr letters. We examined 33 letters of Korean self-immolators, compared with 33 suicide notes of a matched sample of more common suicides. An analysis of intrapsychic factors (suicide as unbearable pain, psychopathology) and interpersonal factors (suicide as murderous impulses and need to escape) revealed that, although one can use the same psychological characteristics or dynamics to understand the deaths, the state of mind of martyrs is more extreme, such that the pain is reported to be even more unbearable. Yet, there are differences, such as there was no ambivalence in the altruistic notes. It is concluded that intrapsychic and interpersonal characteristics are central in understanding martyrs, probably equal to community or societal factors. More forensic study is, however, warranted.

  17. Letter: supplementary pyridoxine given to women using oral contraceptives.

    Science.gov (United States)

    Winston, F

    1975-07-15

    This letter is a response to an article describing the efficacy of administering large doses of tryptophan to depressive patients taking oral contraceptives. This letter-writer argues that the salient action of mood elevation is a result of the supplemental pyridoxine (vitamin B) which ameliorates the deficiency induced by oral contraceptive use that leads to depression resulting from inhibition of synthesis of biogenic amines in the central nervous system. Instead of large doses of tryptophan, which may cause dangerous accumulations of possibly carcinogenic and diabetogenic metabolites when therapy for depression is indicated, pyridoxine should be administered together with the tryptophan; the tryptophan should be discontinued once the deficiency is corrected, although the vitamin therapy should continue throughout oral contraceptive use.

  18. Resource Letter ANP-1: Advances in Neutrino Physics

    Science.gov (United States)

    Goodman, Maury C.

    2016-12-01

    Three of the twelve fundamental fermions in particle physics are neutrinos. It was long thought that neutrinos might be massless, but we now know through the phenomenon of neutrino oscillations that neutrinos have mass. This resource letter will cover the history of the growth in our knowledge about neutrinos since they were first proposed in the 1930s, and also covers some up the upcoming experiments which will further our understanding of neutrino properties. Results from experiments are described that use various sources of neutrinos including nuclear reactors, cosmic rays, accelerators, and supernovae. In this resource letter, the resources that can be used to trace the past, present, and anticipated future advances in neutrino physics are reviewed.

  19. Resource Letter HCMP-1: History of Condensed Matter Physics

    Science.gov (United States)

    Martin, Joseph D.

    2017-02-01

    This Resource Letter provides a guide to the literature on the history of condensed matter physics, including discussions of the development of the field and strategies for approaching its complicated historical trajectory. Following the presentation of general resources, journal articles and books are cited for the following topics: conceptual development; institutional and community structure; social, cultural, and political history; and connections between condensed matter physics and technology.

  20. Covert attention enhances letter identification without affecting channel tuning.

    Science.gov (United States)

    Talgar, Cigdem P; Pelli, Denis G; Carrasco, Marisa

    2004-02-02

    Directing covert attention to the target location enhances sensitivity, but it is not clear how this enhancement comes about. Knowing that a single spatial frequency channel mediates letter identification, we use the critical-band-masking paradigm to investigate whether covert attention affects the spatial frequency tuning of that channel. We find that directing attention to the target location halves threshold energy without affecting the channel's spatial frequency tuning.

  1. LETTER TO THE EDITOR: Explicit finite inverse Hilbert transforms

    Science.gov (United States)

    You, Jiangsheng; Zeng, Gengsheng L.

    2006-06-01

    Recently, Noo and coworkers discovered an explicit inversion formula for the finite Hilbert transform, which is very important to accurate reconstruction from truncated projections. This letter presents two formulae for the finite inverse Hilbert transform using some elementary complex variable analysis. The new formulae do not contain the constant C and the singular endpoints that exist in the formula in Noo et al (2004 Phys. Med. Biol. 49 3903-23).

  2. Letter to Freud: on the plight of psychoanalysis.

    Science.gov (United States)

    Mendes, Dinah M

    2011-12-01

    In the form of a letter, the writer communicates to Freud her appreciation for the incomparable richness and complexity of the psychoanalytic enterprise in its century-long evolution from classical, Freudian origins to new developments in theory and technique. At the same time, concern is expressed about the continuity and survival of psychoanalysis in a cultural milieu that has absorbed its once radical ideas about sexuality and unconscious motivation while resisting its viability as a method of treatment.

  3. Forensic linguistics: Applications of forensic linguistics methods to anonymous letters

    OpenAIRE

    NOVÁKOVÁ, Veronika

    2011-01-01

    The title of my bachelor work is ?Forensic linguistics: Applications of forensic linguistics methods to anonymous letters?. Forensic linguistics is young and not very known branch of applied linguistics. This bachelor work wants to introduce forensic linguistics and its method. The bachelor work has two parts ? theory and practice. The theoretical part informs about forensic linguistics in general. Its two basic aspects utilized in forensic science and respective methods. The practical part t...

  4. Resource Letter PSEn-1: Physics and society: Energy

    Science.gov (United States)

    Hobson, Art

    2007-04-01

    This Resource Letter provides a guide to the physics-related literature about energy-and-society. Journal articles, books, and websites are cited for the following topics: general references, textbooks, other pedagogical resources, population growth, fossil fuels, global warming, nuclear power, side effects of nuclear power, fusion power, renewable resources (including hydroelectric, biofuels, wind, photovoltaics, direct solar, geothermal, hydrogen, and energy storage), energy efficiency, and transportation efficiency.

  5. The “Sin” Analysis in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    邓永秀

    2014-01-01

    The Scarlet Letter,one of the immortal representatives of Romanticism literature makes the American writer Nathaniel Hawthorne known around the world.The unique organization of the novel,the skillful use of symbolism and metaphor demonstrate the writer’s profound insight and unique view of the society and the human nature,which make the“sin”rise to a higher level.

  6. The “Sin” Analysis in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    邓永秀

    2014-01-01

    The Scarlet Letter,one of the immortal representatives of Romanticism literature makes the American writer Nathaniel Hawthorne known around the world.The unique organization of the novel,the skillful use of symbolism and metaphor demonstrate the writer’s profound insight and unique view of the society and the human nature,which make the"sin"rise to a higher level.

  7. Resource Letter DEAU-1: Dark energy and the accelerating universe

    Science.gov (United States)

    Linder, Eric V.

    2008-03-01

    This Resource Letter provides a guide to the literature on dark energy and the accelerating universe. It is intended to be of use to researchers, teachers, and students at several levels. Journal articles, books, and websites are cited for the following topics: Einstein's cosmological constant, quintessence or dynamical scalar fields, modified cosmic gravity, relations to high-energy physics, cosmological probes and observations, terrestrial probes, calculational tools and parameter estimation, teaching strategies and educational resources, and the fate of the universe.

  8. Physics Letters B, Volume 716, Issue 1- Cover Page

    CERN Multimedia

    CERN

    2012-01-01

    The cover page of the Physics Letters B Journal, Volume 716, Issue 1, dedicated to the observation of a new particle in the search for the Standard Model Higgs boson. To celebrate this historical discovery, Elsevier reprinted the ATLAS and the CMS articles together with a foreword by Peter Higgs and the other scientists that predicted the existence of the so-called Higgs boson and published this in a separate booklet.

  9. Analysis of the Sin in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    刘瑾

    2013-01-01

    Nathaniel Hawthorne's novel, The Scarlet Letter, describes the different sins, their different attitudes to sins and their ends and mainly discusses the problems of sin and redemption, which reflects that to live is to suffer from sins and atone for sins, whereas the death is a way of relief and access to rebirth. This paper mainly discusses the novel's theme, namely, the sin committed by the three characters.

  10. Open letter to the Italian Ministry of University and Research

    Directory of Open Access Journals (Sweden)

    O'Grady K

    2008-12-01

    Full Text Available Open letter to the Minister of Italian University. The government should get advice from the best Italian scientists for the necessary reform of the Italian University, with special concern to crucial processes as the appointment of new professors and academic evaluation. The current government proposal for a random draw of evaluation committees in charge for the appointment of new professors is considered as a wrong solution and harmful tool for dealing with such a crucial process.

  11. Biosimilars approval process.

    Science.gov (United States)

    Zuñiga, Leyre; Calvo, Begoña

    2010-04-01

    For similar biological medicinal products, the so-called biosimilars, clinical trials are required rather than just the bioequivalence studies required to support the registration of a generic small molecule drug product. The EU Directive 2001/83/EC, as amended, stated that where a biological medicinal product which is similar to a reference biological product, does not meet the conditions in the definition of generic medicinal products the results of appropriate pre-clinical tests or clinical trials relating to these conditions must be provided. The challenge is to determine the exact nature of the non-clinical and clinical programme required to gain regulatory approval. The applicant is encouraged to provide a detailed description of the strategy used to demonstrate the biosimilar and the reference product have similar profiles in terms of quality, safety and efficacy. The extent to which comparability can be proven will have quite an impact on how many non-clinical and clinical studies the biosimilar applicant will be required to conduct. The dossier submitted by the applicant to the EMEA should cover all aspects of the comparability assessment and must include data on possible unwanted immune reactions to the therapeutic protein. Post-marketing pharmacovigilance plans are also expected to be included in the biosimilar dossier.

  12. Gender Differences in Iranian EFL Students’ Letter Writing

    Directory of Open Access Journals (Sweden)

    Somaye Hamdi asl

    2012-11-01

    Full Text Available Studies regarding gender differences in EFL context have been done for many years. However, it seems that writing, which is a vital skill in academic issues, has gained much less attention in this area. In addition, not having enough knowledge of gender differences for teachers is one of the main barriers of language learning. The current study examines gender differences in Iranian EFL students’ letter writing in terms of 13 linguistic features mentioned in Mulac, Bradac, & Gibbons (2001. The results of this study showed significant differences toward the use of some linguistic features. Female participants tended to use more “I” references, references to quantity, references to emotions, uncertainty verbs, sentence initial adverbials and judgmental adjectives. In addition, the results showed than women tended to be wordier than men in terms of total number of words. Men, on the other hand, exceeded women on a number of linguistic dimensions including locatives, mean length sentence and dependent clauses. Moreover, elliptical sentences were not used by female participants at all and few male participants used them in their letters. Therefore, this study demonstrated gender differences in Iranian EFL students’ letter writing. These dissimilarities between genders in EFL can be contributed to many aspects such as educational instructions, teachers, and cultural differences. It also illustrated teachers’ perspectives of gender regarding students’ writing.Keywords: Gender, Writing, Linguistic Features

  13. Letters from Ainsworth: Contesting the ‘Organization’ of Attachment

    Science.gov (United States)

    Landa, Sophie; Duschinsky, Robbie

    2013-01-01

    As Main (1999) noted in her obituary for Mary Ainsworth, ‘she was interacting weekly by letter and manuscript with her mentor and friend, John Bowlby, and their academic correspondence formed an important part of her, and implicitly our, life.’ These letters of Ainsworth to John Bowlby during the 1980s, available in the Wellcome Trust Library in London, contain valuable reflections on the work of her pupils to extend her system of classifying infant behaviour in the Strange Situation Procedure. Mary Main proposed a D classification and interpreted such behaviour as a breakdown in an ABC strategy caused by a conflict between a disposition to approach and flee from the caregiver. Patricia Crittenden extended the subtypes of A and C, using a developmental model of information processing, and observed that they could be used together in A/C combinations. These letters offer insight into Ainsworth’s intellectual rationale for encouraging both Main and Crittenden in their conflicting endeavours. PMID:23667365

  14. [The letters preserved by Vittorio Benussi 'Fund Sante de Sanctis'].

    Science.gov (United States)

    Cicciola, Elisabetta; Lombardo, Giovanni Pietro

    2008-01-01

    Through the publication of a previously unpublished exchange of letters, this paper examines the relations between the Italian psychologists Sante De Sanctis and Vittorio Benussi. The collaboration between the two scholars, which emerges from the 23 letters presented here, was solid and long-lasting both on the scientific plane and on the personal one. It began in 1905 on the occasion of the Fifth International Congress of Psychology held in Rome, and it terminated more than 20 years later, in 1927, with the death of Benussi, who took his own life. The Benussi-De Sanctis correspondence (1905-1927) is part of a archive, denominated the "Sante De Sanctis (1893-1935) Archive," which has been recently constituted on the basis of commonly shared archival criteria. In order to facilitate a better understanding of the general context of Sante De Sanctis's scientific relations, the Appendix contains an analytical list, divided into 170 files, of all those who sent letters to him between 1893 and 1935.

  15. Accurate reading with sequential presentation of single letters

    Directory of Open Access Journals (Sweden)

    Nicholas Seow Chiang Price

    2012-10-01

    Full Text Available Rapid, accurate reading is possible when isolated, single words from a sentence are sequentially presented at a fixed spatial location. We investigated if reading of words and sentences is possible when single letters are rapidly presented at the fovea under user-controlled or automatically-controlled rates. When tested with complete sentences, trained participants achieved reading rates of over 60 words/minute and accuracies of over 90% with the single letter reading (SLR method and naive participants achieved average reading rates over 30 wpm with >90% accuracy. Accuracy declined as individual letters were presented for shorter periods of time, even when the overall reading rate was maintained by increasing the duration of spaces between words. Words in the lexicon that occur more frequently were identified with higher accuracy and more quickly, demonstrating that trained participants have lexical access. In combination, our data strongly suggest that comprehension is possible and that SLR is a practicable form of reading under conditions in which normal scanning of text is not possible, or for scenarios with limited spatial and temporal resolution such as patients with low vision or prostheses.

  16. ERP Indices of Stimulus Prediction in Letter Sequences

    Directory of Open Access Journals (Sweden)

    Edith Kaan

    2014-10-01

    Full Text Available Given the current focus on anticipation in perception, action and cognition, including language processing, there is a need for a method to tap into predictive processing in situations in which cue and feedback stimuli are not explicitly marked as such. To this aim, event related potentials (ERPs were obtained while participants viewed alphabetic letter sequences (“A”, “B”, “C”, “D”, “E”, …, in which the letters were highly predictable, and random sequences (“S”, “B”, “A”, “I”, “F”, “M”, …, without feedback. Occasionally, the presentation of a letter in a sequence was delayed by 300 ms. During this delay period, an increased negativity was observed for predictive versus random sequences. In addition, the early positivity following the delay was larger for predictive compared with random sequences. These results suggest that expectation-sensitive ERP modulations can be elicited in anticipation of stimuli that are not explicit targets, rewards, feedback or instructions, and that a delay can strengthen the prediction for a particular stimulus. Applications to language processing will be discussed.

  17. Approval plans issues and innovations

    CERN Document Server

    Katz, Linda S

    2013-01-01

    How can you, as an acquisition librarians, keep current on the output of hundreds of publishers? The answer, of course, is that you cannot. For over 30 years, approval plans have been used by librarians to acquire current titles, save staff time, and build core collections. Even today, these reasons seem appropriate, as libraries try to maintain up-to-date collections and control personnel and operating budgets. However, as shown in Approval Plans: Issues and Innovations, the use of approval plans is not so simple and straightforward; their use is subject to complex procedures and policies--an

  18. Letter Frequency Analysis of Lithuanian and Other Languages Using the Latin Alphabet

    Directory of Open Access Journals (Sweden)

    Gintautas Grigas

    2015-12-01

    Full Text Available It is important to evaluate specificities of alphabets, particularly the letter frequencies while designing keyboards, analyzing texts, designing games based on alphabets, and doing some text mining. In order to adequately compare lettter frequences of Lithuanian language to other languages in the Internet space, Wikipedia source was selected which content is common to different languages. The method of letter frequency jumps is used. The main attention is paid to the analysis of letter frequencies at the boundary between native letters and foreign letters used in Lithuanian and other languages.

  19. 76 FR 70190 - Self-Regulatory Organizations; Financial Industry Regulatory Authority, Inc.; Order Approving...

    Science.gov (United States)

    2011-11-10

    ... October 20, 2011 (``Shatto Letter''); letter from Naphtali M. Hamlet, Investor, dated October 21, 2011 (``Hamlet Letter''); letter from Daniel Zinn, General Counsel, OTC Markets Group Inc., dated October 20... reported for public dissemination. \\12\\ See Shatto Letter; Hamlet Letter. \\13\\ See Shatto Letter. \\14\\...

  20. Verse Letter from Gregory of Nazianzus to Vitalianus

    Directory of Open Access Journals (Sweden)

    Erika Brodňanská

    2012-12-01

    Full Text Available The article offers a complex view of the poetic letter of Gregory of Nazianzus II, II, 3 Ad Vitalianum, which has not yet been the subject of modern criticism. The letter is a plea by Vitalianus’ banished sons for their father to take them back. Based on the manuscript tradition, the article’s author concludes that the fictional author of the letter is the son Phocas rather than Peter. The disrupted relationship between father and sons is reflected in both the content of the poem and the forms of salutations used: the seemingly positive epithets φέριστε, μακάρτατε, and φίλε; forms of address which directly express a certain distance and coldness (μέγα φέρτατε, ὦ ἄνα, or even animosity towards the father (ὀλοώτατε δαῖμον, ὦ κακόβουλε. The poetic letter has a concentric structure (A; B; C; D; E; F; G; F´; E´; D´; C´; B´; A´, with individual com­ponents linked for the most part thematically. The letter is written in dactylic hexameter. The most frequently used metre in the verses is the holodactyl, and the most frequent caesura is the caesura post tertium trochaeum. As far as the breach of Hermann’s bridge in verses is concerned, and based on the understanding of the term ‘word’ in metrics, the author of the article concludes that in the majority of cases the breach is only ‘visual’, and cannot be detected when listened to. Gregory did not avoid three true hiatuses; and in two verses, in order to keep the rhythm of dactylic hexameter, it is essential to measure a long syllable as a short one. However, metric errors may be related to prosodic licence.

  1. ABC versus QWERTZ: interference from mismatching sequences of letters in the alphabet and on the keyboard.

    Science.gov (United States)

    Kozlik, Julia; Neumann, Roland; Kunde, Wilfried

    2013-08-01

    Letters have a position in the alphabet and they have a position on standard personal computer keyboards. The present study explored the consequences of compatibility between spatial codes representing letter position in the alphabet and on the keyboard. In Experiment 1, participants responded faster to letter dyads in an alphabetic order judgment task, when the letters' alphabetical order matched their left to right order on the keyboard. In Experiment 2, compatible dyads were typed more quickly than incompatible dyads. Finally, in Experiments 3 and 4, letter dyads with compatible alphabetical and keyboard sequences of letters were more preferred than dyads with incompatible orders. Together, these results suggest that the perception of letters concurrently activates 2 representations of ordinal sequences. Compatibility between these representations enhances performance as well as affective evaluations. Limitations of this alphabet-keyboard compatibility effect as well as implications for the development of formal typing courses and computer keyboard design are discussed.

  2. Drugs Approved for Liver Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for liver cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  3. Drugs Approved for Vulvar Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for vulvar cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  4. Drugs Approved for Esophageal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for esophageal cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  5. Drugs Approved for Vaginal Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) to prevent vaginal cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  6. Drugs Approved for Endometrial Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for endometrial cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  7. Drugs Approved for Penile Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for penile cancer. The list includes generic names and brand names. The drug names link to NCI’s Cancer Drug Information summaries.

  8. Is It Really FDA Approved?

    Science.gov (United States)

    ... does not approve cosmetics. Examples of cosmetics are perfumes, makeup, moisturizers, shampoos, hair dyes, face and body ... and provide the agency with a notification before marketing a new formula. FDA conducts yearly inspections of ...

  9. Electronic Voucher Approval - Financial Management

    Data.gov (United States)

    US Agency for International Development — This process provides a workflow and eSignature capability which allows the CFO to router vouchers for review and electronic signature approval to COTRs in AIDW. It...

  10. Drugs Approved for Skin Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for skin cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  11. Drugs Approved for Kaposi Sarcoma

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for Kaposi sarcoma. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  12. Drugs Approved for Bone Cancer

    Science.gov (United States)

    This page lists cancer drugs approved by the Food and Drug Administration (FDA) for bone cancer. The list includes generic names and brand names. The drug names link to NCI's Cancer Drug Information summaries.

  13. Elosulfase alfa: first global approval.

    Science.gov (United States)

    Sanford, Mark; Lo, Jin Han

    2014-04-01

    Elosulfase alfa (Vimizim™) is a recombinant form of N-acetylgalactosamine-6-sulfatase (GALNS) that was developed by BioMarin Pharmaceutical Inc. as an enzyme replacement therapy for patients with mucopolysaccharidosis type IVA (MPS IVA), also known as Morquio A syndrome. Patients with MPS IVA have a GALNS deficiency, which results in serious musculoskeletal, cardiorespiratory and other system disturbances. Elosulfase alfa was approved by the US FDA on 14 February 2014 for the treatment of MPS IVA. The European Medicines Agency Committee for Medicinal Products for Human Use (CHMP) has recently recommended that elosulfase alfa be approved for use in the EU in the same indication. Within the last year, the manufacturer has also filed applications for approval for the use of elosulfase alfa in MPS IVA in Brazil, Australia, Canada and Mexico. This article summarizes the milestones in the development of elosulfase alfa leading to its first global approval in MPS IVA.

  14. Drugs Approved for Prostate Cancer

    Science.gov (United States)

    ... 2015 2014 2013 2012 Media Resources Media Contacts Multicultural ... This page lists cancer drugs approved by the Food and Drug Administration (FDA) for prostate cancer. The list includes generic ...

  15. Trulance Approved for Chronic Constipation

    Science.gov (United States)

    ... news/fullstory_163171.html Trulance Approved for Chronic Constipation Drug designed to stimulate upper gastrointestinal tract To ... U.S. Food and Drug Administration to treat persistent constipation of unknown (idiopathic) cause in adults. Some 42 ...

  16. 9 CFR 147.52 - Approved tests.

    Science.gov (United States)

    2010-01-01

    ... 9 Animals and Animal Products 1 2010-01-01 2010-01-01 false Approved tests. 147.52 Section 147.52... Approved Tests § 147.52 Approved tests. (a) The procedures for the bacteriological examination of poultry and poultry environments described in this part are approved tests for use in the NPIP. In...

  17. Resource Letter BSSMF-1: Biological Sensing of Static Magnetic Fields

    Science.gov (United States)

    Finegold, Leonard

    2012-10-01

    This Resource Letter provides a guide to the literature on the effects of static (time-invariant) magnetic fields B on life, concentrating on how selected creatures sense/detect B. Journal articles, books, and previous and future electronically accessible media are cited for the following topics: history, the magnetic sensing/detection of B by creatures from bacteria to bugworms to butterflies to bees to birds to bats to bovines to beings (human), some of the mechanisms of effects at the developmental and cellular levels, experimental pitfalls, claimed healing effects of B, some medical uses of magnets, and cosmetics. The field presents a fascinating, evolving saga.

  18. Why the DSM? – Letter to the Editors

    Directory of Open Access Journals (Sweden)

    Cozic, Jean-Yves

    2014-03-01

    Full Text Available The psychological experience is not always in register to pathology. Classification must be as close as possible to the clinical examination, but also respectful of human principles. For a long time classifications have had a Linnaean feel; the concern of psychatrists with little leeway for therapeutic action. Professor PELICIER was accustomed to saying that this classifications could be called “herbarium of the flowers of Evil”, with a capital letter on Flowers, recalling one of our great poets, Charles Baudelaire, who described melancholy so well: “When the low, heavy sky weighs like a lid on the groaning spirit, victim of long ennui”.

  19. Charles Dickens and the Cat Paw Letter Opener

    Directory of Open Access Journals (Sweden)

    Jenny Pyke

    2014-10-01

    Full Text Available This article explores the sensory expectations around Victorian taxidermy, beginning with Charles Dickens’s letter opener made from the paw of his favourite cat and moving to a discussion of 'Our Mutual Friend'. I suggest that in a mid-Victorian moment in which work and laziness are polarized as the available moral, economic, and social categories, a desire for stillness, a space that is neither work nor laziness, exists in the encounter with taxidermied animals. The taxidermied animal allows energy and stillness to coexist.

  20. Science Letters: Lattice type transmission line of negative refractive index

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    In this letter, we introduce a novel passive transmission line of negative refractive index (i.e., left-handedness) based on identical symmetrical lattice type structures [thus called "lattice type transmission line" (LT-TL)]. The dispersion characteristic and the transmission response of the proposed LT-TL are analyzed. While all the other left-handed passive transmission lines are of high pass, the present passive left-handed transmission line is of low pass. Compared with a conventional transmission line, the LT-TL has a phase shift of 180° in the entire wide pass-band.

  1. The "Letter" and the play of the correspondence

    OpenAIRE

    Joacy Ghizzi Neto

    2013-01-01

    The present essays has as it bottom line the short story “The Purloined Letter” by Edgar Alan Poe and the respectives analysis done by Jacques Lacan in “O Seminário A carta roubada” (Escritos, 1998) and by Jacques Derrida in “O carteiro da verdade” (O cartão-postal, 2007), beyond the reading by Nancy and Labarthe in O título da letra and also Rene Major in Lacan com Derrida, with the wager at the potency of the significant letter/lettre that has a double meaning as “carta” and as “letra”, wit...

  2. A Finite Abelian Group of Two-Letter Inversions

    Directory of Open Access Journals (Sweden)

    Sherwin E. Balbuena

    2015-11-01

    Full Text Available In abstract algebra, the study of concrete groups is fundamentally important to beginners. Most commonly used groups as examples are integer addition modulo n, real number addition and multiplication, permutation groups, and groups of symmetry. The last two examples are finite non-abelian groups and can be investigated with the aid of concrete representations. This study presents a finite abelian group of inversions of two letter symbols with vertical and horizontal axes of symmetry and whose binary operation is established through motions like alternation, rotation, reflection, and a combination of two or all motions.

  3. The Description Of Characters In The Novel The Scarlet Letter

    OpenAIRE

    Sirait, Wahyu Alamsyah

    2016-01-01

    Literature is a kind of imaginative writing. It reflects a problem of life done by human being. Novel is one of literary works that has intrinsic elements. Studying intrinsic elements in a novel, it means to study life experience of group human being through a novel. The writer analyzes the theme in novel The shining by Stephen King 's. therefore, this paper is entitled become : THE DESCRIPTION OF CHARACTERS IN THE NOVEL THE SCARLET LETTER. This writing is a description on the characters used...

  4. Resource Letter PTG-1: Precision Tests of Gravity

    CERN Document Server

    Will, Clifford M

    2010-01-01

    This resource letter provides an introduction to some of the main current topics in experimental tests of general relativity as well as to some of the historical literature. It is intended to serve as a guide to the field for upper-division undergraduate and graduate students, both theoretical and experimental, and for workers in other fields of physics who wish learn about experimental gravity. The topics covered include alternative theories of gravity, tests of the principle of equivalence, solar-system and binary-pulsar tests, searches for new physics in gravitational arenas, and tests of gravity in new regimes, involving astrophysics and gravitational radiation.

  5. WRITING FOR A REAL AUDIENCE: A LETTER-EXCHANGE PROJECT

    Institute of Scientific and Technical Information of China (English)

    2001-01-01

    In an EFL class, writing for a real audience can bring aboutmany inherent educational benefits. However, this is often ne-glected by many language teachers. This paper reports on the re-sults obtained from using a writing for a real audience project inan Intensive Reading course for non-English majors. Students inthis project wrote letters to their partners in the target languageand shared information with each other. The author found thatthe process of writing for a real audience can not only help stu-dents practice using the target language but also can encouragethem to overcome writing apprehension.

  6. Effects of social approval bias on self-reported fruit and vegetable consumption: a randomized controlled trial

    Directory of Open Access Journals (Sweden)

    Marcus Al C

    2008-06-01

    Full Text Available Abstract Background Self-reports of dietary intake in the context of nutrition intervention research can be biased by the tendency of respondents to answer consistent with expected norms (social approval bias. The objective of this study was to assess the potential influence of social approval bias on self-reports of fruit and vegetable intake obtained using both food frequency questionnaire (FFQ and 24-hour recall methods. Methods A randomized blinded trial compared reported fruit and vegetable intake among subjects exposed to a potentially biasing prompt to that from control subjects. Subjects included 163 women residing in Colorado between 35 and 65 years of age who were randomly selected and recruited by telephone to complete what they were told would be a future telephone survey about health. Randomly half of the subjects then received a letter prior to the interview describing this as a study of fruit and vegetable intake. The letter included a brief statement of the benefits of fruits and vegetables, a 5-A-Day sticker, and a 5-a-Day refrigerator magnet. The remainder received the same letter, but describing the study purpose only as a more general nutrition survey, with neither the fruit and vegetable message nor the 5-A-Day materials. Subjects were then interviewed on the telephone within 10 days following the letters using an eight-item FFQ and a limited 24-hour recall to estimate fruit and vegetable intake. All interviewers were blinded to the treatment condition. Results By the FFQ method, subjects who viewed the potentially biasing prompts reported consuming more fruits and vegetables than did control subjects (5.2 vs. 3.7 servings per day, p Conclusion Self-reports of fruit and vegetable intake using either a food frequency questionnaire or a limited 24-hour recall are both susceptible to substantial social approval bias. Valid assessments of intervention effects in nutritional intervention trials may require objective measures of

  7. Electronic Approval of Invoices (AEF)

    CERN Multimedia

    2003-01-01

    With a view to the simplification of administrative procedures, AS and FI Divisions have drawn up a new procedure for the electronic approval of invoices via the EDH application. The aim of this new procedure is to rationalise the invoice approval process, notably by eliminating paper copies from the approval circuit. This will simplify the processing of invoices and facilitate their timely settlement, while at the same time maintaining a high level of security. This new procedure, in its current phase, will be gradually implemented from 1 November 2003 onwards. For clarification and further information, please see: http://ais.cern.ch/projs/AEF/help/help.htm . Finance Division, Accounts Payable Tel.: 7.22.95

  8. 77 FR 8865 - Public Water System Supervision Program Approval for the State of Illinois; Tentative Approval

    Science.gov (United States)

    2012-02-15

    ... From the Federal Register Online via the Government Publishing Office ENVIRONMENTAL PROTECTION AGENCY Public Water System Supervision Program Approval for the State of Illinois; Tentative Approval... State of Illinois submitted a primacy application for its approved Public Water System...

  9. Examination and Comparison of Phrases of Some Old Letters of Ascension (to Heaven and It's Comparison with Shafiee Kadkani's Letter

    Directory of Open Access Journals (Sweden)

    کهدویی کهدویی

    2011-05-01

    Full Text Available Human voyage to the world of ultra sense is a matter of discourses which was widely discussed between nations and the various schools of philosophy, language and many people including leaders of religions and thoughts branches confessed doing such voyages and left some literary reports of their mystical and dreamy travel. The oldest and newest of these reports are shown in this paper and them between the voyages that traditional people have reported and the letter of ascension of M.R.SH.KK as ample of a modern man which is available we make some comparisons in different dimensions , dealing with unconscious and interfering of super human in forming their phrases . This survey shows that most of these voyages could have certain occurrences, and could explain them in scientific view and particularly based on Yung's ideas. In evaluating a part of phrases of these voyages it has been shown that the similarities and common points of these ascensions is related to the beliefs, mortification and deliberations that cause these voyages in one side and in the other side is related to the influence of the most formers and the letter voyages; also by comparing the two traditional and modern groups of passengers of the invisible world. Through submitting and explaining their documentary reports, the ideology role of these two groups is described in creating the elements of these phrases and mean while the commitment and mission of human is described based on considering the traditional definition of human as a speaking animal and the definition of moderns as a searching animal in human general ascension , and at the end it is reminded that the modern human is trying to encourage and prepare the collective conscience of human to clear and improve the society through conscious movement and describing manners of painful souls in world of spirits and using the fear strategy. The reason of fear less critic of poets in the last part of the letter of ascension of

  10. A Study on the Application in Business Letters of Cooperative Principle

    Institute of Scientific and Technical Information of China (English)

    王莹

    2016-01-01

    With the rapid development of science and technology, English business letters have become one of the most crucial parts in foreign trade. English business letters play an important role in foreign trade, which aims to acquire information, make effective communication, deal with related matters, maintain friendly business relations and proceed regular business contacts. As an effective bridge and cooperative bond, English business letters receive its popularity in joint ventures. The leaders focus on the application of the English business letters.The paper focus on the study of English business letters through cooperative principle, letting users of English business letters have a more profound and comprehensive understanding. Therefore, it is better to guide and get desired outcome.

  11. BIBLICAL METAPHORS IN LETTERS OF LEV OF OPTINA

    Directory of Open Access Journals (Sweden)

    Svetlana Olegovna Zakharchenko

    2014-11-01

    Full Text Available This article presents the first analysis of tropes in the letters of the first Elder Lev (Nagolkin of Optina Pustyn Monastery (Opta’s hermitage – i. e. proverbs, allusions, allegories periphrasis and metaphors. Elder Lev most frequently used such tropes as "the storm of temptations", "the heart field", "happy harvest", "rags of the passions", "the marriage of the soul", "verbal sheep", "soldier of Christ", "spiritual milk", "the mind’s wolf", "a log of pride". One special thing about these tropes is that they blend together severalbiblical quotations and the Gospel images. Both simple and extended metaphors are used, and all the metaphors in the letters of St. Lev of Optina have a special function: they actualize biblical events, describe symbolically the inner world of a person and show the way to the salvation of the soul. It is typical of the Elder to use his own unique tropes, which are very diff erent from the traditional poetic images of the Russian literature of the 19th century.

  12. The Letter of Jude and Graeco-Roman Invective

    Directory of Open Access Journals (Sweden)

    Alicia J. Batten

    2014-02-01

    Full Text Available Many have attempted to identify the opponents in Jude and have addressed the manner in which the author characterises this group. Moreover, scholars have expended considerable energy on the analysis and explication of Jude’s rhetorical structure and style, and there is wide consensus that as a text, Jude is a sophisticated letter. However, less work has attended to the evaluation of Jude within the tradition of Graeco-Roman invective. In comparing verses from Jude to some examples from such literature, we find similar themes. In particular, the letter of Jude and some Graeco-Roman moralists engage in a particular tactic to undermine, even destroy, the character of their opponents. They both present them as effeminates, which, although a stereotype, is one of the worst insults a writer or orator could wage against an adversary. This article argues that Jude engages in such character assassination, invoking effeminacy in the manner that he describes his opponents’ behaviour, and placing them in a long line of debauched and condemned figures from ages past.

  13. The "Letter" and the play of the correspondence

    Directory of Open Access Journals (Sweden)

    Joacy Ghizzi Neto

    2013-11-01

    Full Text Available The present essays has as it bottom line the short story “The Purloined Letter” by Edgar Alan Poe and the respectives analysis done by Jacques Lacan in “O Seminário A carta roubada” (Escritos, 1998 and by Jacques Derrida in “O carteiro da verdade” (O cartão-postal, 2007, beyond the reading by Nancy and Labarthe in O título da letra and also Rene Major in Lacan com Derrida, with the wager at the potency of the significant letter/lettre that has a double meaning as “carta” and as “letra”, with its potency, as letter, as possible literature. The present work concern aswell with another readings, about epistolography, by Josefina Ludmer, Emile Cioran, Juan José Saer, Liliana Heer, Silviano Santiago. The present work approaches aswell the reading by Michel Foucault in “A escrita de si” (O que é um autor?, 1992 arguing that the correspondence as a way of “escrita de si”, despite it is destinated, in principle to an other. The present essays has as principle objective to think the proceeding of correspondence between artists/poets as a play of ambivalent positions, and not as how a static share between the remitter and the receiver.

  14. Letter-case information and the identification of brand names.

    Science.gov (United States)

    Perea, Manuel; Jiménez, María; Talero, Fernanda; López-Cañada, Soraya

    2015-02-01

    A central tenet of most current models of visual-word recognition is that lexical units are activated on the basis of case-invariant abstract letter representations. Here, we examined this assumption by using a unique type of words: brand names. The rationale of the experiments is that brand names are archetypically printed either in lowercase (e.g., adidas) or uppercase (e.g., IKEA). This allows us to present the brand names in their standard or non-standard case configuration (e.g., adidas, IKEA vs. ADIDAS, ikea, respectively). We conducted two experiments with a brand-decision task ('is it a brand name?'): a single-presentation experiment and a masked priming experiment. Results in the single-presentation experiment revealed faster identification times of brand names in their standard case configuration than in their non-standard case configuration (i.e., adidas faster than ADIDAS; IKEA faster than ikea). In the masked priming experiment, we found faster identification times of brand names when they were preceded by an identity prime that matched its standard case configuration than when it did not (i.e., faster response times to adidas-adidas than to ADIDAS-adidas). Taken together, the present findings strongly suggest that letter-case information forms part of a brand name's graphemic information, thus posing some limits to current models of visual-word recognition.

  15. Initial and noninitial name-letter preferences as obtained through repeated letter rating tasks continue to reflect (different aspects of) self-esteem.

    Science.gov (United States)

    Hoorens, Vera; Takano, Keisuke; Franck, Erik; Roberts, John E; Raes, Filip

    2015-09-01

    We tested the usefulness of name-letter preference scores as indirect indicators of self-esteem by exploring whether multiple unsupervised self-administrations of letter rating tasks within a short period of time yield useful data. We also examined whether preferences for initials and noninitial name-letters tap different aspects of self-esteem. Participants from a community sample (N = 164; 58 men and 106 women, 17-67 years, Mage = 34.57, SD = 13.28) completed daily letter rating tasks and state self-esteem questionnaires for 7 consecutive days. They also completed a trait self-esteem questionnaire on the first measurement day as well as 6 months later. Preference scores for first-name initials were stronger but more unstable than preference scores for other name-letters. Preferences for first-name initials were primarily associated with directly measured state self-esteem whereas preferences for noninitials were primarily associated with directly measured trait self-esteem even if the latter was measured 6 months later. Thus, we showed that preferences for initials and noninitials are not simply interchangeable. Previous letter rating studies, which almost exclusively used initial preferences, should be interpreted in terms of state rather than trait self-esteem. In future studies, researchers should focus on the name-letter preference that reflects the aspect of self-esteem they wish to address.

  16. The Long and Short of Genetic Counseling Summary Letters: A Case-control Study.

    Science.gov (United States)

    Roggenbuck, J; Temme, R; Pond, D; Baker, J; Jarvis, K; Liu, M; Dugan, S; Mendelsohn, N J

    2015-08-01

    Genetic counseling summary letters are intended to reinforce information received during genetic counseling, but little information is available on patient/family responses to these letters. We conducted a case-control study to assess the effectiveness of two different letter formats. Parents of children receiving a new diagnosis were enrolled. The control group (n = 85) received a genetic counseling summary letter in a narrative format, 4-5 pages in length. After the control enrollment period, genetic counselors were trained by a professional medical writer to develop a concise letter format. The case group (n = 64) received a concise letter, approximately 1.5 pages in length, utilizing simple sentences, lay terms, and lists/bullet points. Parents completed a survey 4 weeks after the visit to rate the letter's format, usefulness, and their emotional reaction. Results show that parents in the case group rated the letter more highly (p = 0.023), particularly in the emotional response dimension (rating changes in anxiety, depression, fear, ability to cope, and confidence in response to the letter). Parents in the case group also rated the genetic counseling session more highly (p = 0.039). In the control group, parents without a college degree were more likely to rate the letter as too long and the level of medical detail as too high. In the case group, no significant differences were seen between parents with or without a college degree. These data suggest that a short genetic counseling summary letter is rated higher by parents, and is particularly associated with a more positive emotional reaction. A short letter format highlighting the basic facts related to the genetic condition may be more useful to parents of diverse educational backgrounds, and may support a positive emotional adaptation at the time of a new diagnosis. Genetic counselors may benefit from specific instruction in medical and educational writing.

  17. Parallel public spheres: distance and discourse in letters to the editor.

    Science.gov (United States)

    Perrin, Andrew J; Vaisey, Stephen

    2008-11-01

    This article examines letters to the editor as one of the ways citizens seek to enact a public sphere using technological mediation. Using a sample of all letters received by a metropolitan newspaper during a three-month period (N = 1,113), the authors demonstrate that the tone and argumentative styles of letters differ with the scope of the issues the letters address. Local issues evoke more reasoned, conciliatory tones, while issues beyond the local context evoke more emotional, confrontational tones, even after controlling for individual writers' characteristics and anger as a motivation to write.

  18. Impaired letter-string processing in developmental dyslexia: what visual-to-phonology code mapping disorder?

    Science.gov (United States)

    Valdois, Sylviane; Lassus-Sangosse, Delphine; Lobier, Muriel

    2012-05-01

    Poor parallel letter-string processing in developmental dyslexia was taken as evidence of poor visual attention (VA) span, that is, a limitation of visual attentional resources that affects multi-character processing. However, the use of letter stimuli in oral report tasks was challenged on its capacity to highlight a VA span disorder. In particular, report of poor letter/digit-string processing but preserved symbol-string processing was viewed as evidence of poor visual-to-phonology code mapping, in line with the phonological theory of developmental dyslexia. We assessed here the visual-to-phonological-code mapping disorder hypothesis. In Experiment 1, letter-string, digit-string and colour-string processing was assessed to disentangle a phonological versus visual familiarity account of the letter/digit versus symbol dissociation. Against a visual-to-phonological-code mapping disorder but in support of a familiarity account, results showed poor letter/digit-string processing but preserved colour-string processing in dyslexic children. In Experiment 2, two tasks of letter-string report were used, one of which was performed simultaneously to a high-taxing phonological task. Results show that dyslexic children are similarly impaired in letter-string report whether a concurrent phonological task is simultaneously performed or not. Taken together, these results provide strong evidence against a phonological account of poor letter-string processing in developmental dyslexia.

  19. Alkylbenzene Project in Xinjiang Approved

    Institute of Scientific and Technical Information of China (English)

    Zhou Weiyong

    1996-01-01

    @@ The feasibility study on alkylbenzene project in Dushanzi, Xinjiang Uygur Autonomous Region, submitted jointly by the government of Xinjiang UygurAutonomous Region and China National Petroleum Corporation (CNPC), has been approved by State Council recently,after pass appraisa l by China International Engineering Consulting Corporation entrusted by State Planning Committee.

  20. Trouble Spots in Online Direct-to-Consumer Prescription Drug Promotion: A Content Analysis of FDA Warning Letters

    Directory of Open Access Journals (Sweden)

    Hyosun Kim

    2015-12-01

    Full Text Available Background For the purpose of understanding the Food and Drug Administration’s (FDA’s concerns regarding online promotion of prescription drugs advertised directly to consumers, this study examines notices of violations (NOVs and warning letters issued by the FDA to pharmaceutical manufacturers. Methods The FDA’s warning letters and NOVs, which were issued to pharmaceutical companies over a 10-year period (2005 to 2014 regarding online promotional activities, were content-analyzed. Results Six violation categories were identified: risk information, efficacy information, indication information, product labeling, material information issues, and approval issues. The results reveal that approximately 95% of the alleged violations were found on branded drug websites, in online paid advertisements, and in online videos. Of the total 179 violations, the majority of the alleged violations were concerned with the lack of risk information and/or misrepresentation of efficacy information, suggesting that achieving a fair balance of benefit versus risk information is a major problem with regard to the direct-to-consumer advertising (DTCA of prescription drugs. In addition, the character space limitations of online platforms, eg, sponsored links on search engines, pose challenges for pharmaceutical marketers with regard to adequately communicating important drug information, such as indication information, risk information, and product labeling. Conclusion Presenting drug information in a fair and balanced manner remains a major problem. Industry guidance should consider addressing visibility and accessibility of information in the web environment to help pharmaceutical marketers meet the requirements for direct-to-consumer promotion and to protect consumers from misleading drug information. Promotion via social media warrants further attention, as pharmaceutical manufacturers have already begun actively establishing a social media presence, and the

  1. Trouble Spots in Online Direct-to-Consumer Prescription Drug Promotion: A Content Analysis of FDA Warning Letters

    Science.gov (United States)

    Kim, Hyosun

    2015-01-01

    Background: For the purpose of understanding the Food and Drug Administration’s (FDA’s) concerns regarding online promotion of prescription drugs advertised directly to consumers, this study examines notices of violations (NOVs) and warning letters issued by the FDA to pharmaceutical manufacturers. Methods: The FDA’s warning letters and NOVs, which were issued to pharmaceutical companies over a 10-year period (2005 to 2014) regarding online promotional activities, were content-analyzed. Results: Six violation categories were identified: risk information, efficacy information, indication information, product labeling, material information issues, and approval issues. The results reveal that approximately 95% of the alleged violations were found on branded drug websites, in online paid advertisements, and in online videos. Of the total 179 violations, the majority of the alleged violations were concerned with the lack of risk information and/or misrepresentation of efficacy information, suggesting that achieving a fair balance of benefit versus risk information is a major problem with regard to the direct-to-consumer advertising (DTCA) of prescription drugs. In addition, the character space limitations of online platforms, eg, sponsored links on search engines, pose challenges for pharmaceutical marketers with regard to adequately communicating important drug information, such as indication information, risk information, and product labeling. Conclusion: Presenting drug information in a fair and balanced manner remains a major problem. Industry guidance should consider addressing visibility and accessibility of information in the web environment to help pharmaceutical marketers meet the requirements for direct-to-consumer promotion and to protect consumers from misleading drug information. Promotion via social media warrants further attention, as pharmaceutical manufacturers have already begun actively establishing a social media presence, and the FDA has thus

  2. Lost and Found, Letters and Methods: Assessing Attitudes toward Chiropractic and Medical Care

    Directory of Open Access Journals (Sweden)

    Hannah Kern

    2010-10-01

    Full Text Available Attitudes toward traditional and chiropractic medicine were compared using Milgram's lost letter technique. A total of 192 letters were placed on the windshields of vehicles in parking lots at six restaurants and department stores in each of four quadrants of a medium-sized, Southeastern city. These letters were addressed to "Admissions" at either a fictitious Institute of Medicine or Institute of Chiropractic Care. Return addresses included either a male or a female name. Thus, those who found a lost letter were faced with the option of returning or not returning a letter from either a male or a female, addressed to an Institute of traditional or non-traditional medicine. After examining previous studies which had used the lost letter technique, numerous methodological improvements were implemented. For example, letters were randomly assigned to potential drop spots for each of 24 study locations (six study locations in each of four city quadrants, and a Latin square design was used to control for possible order effects in the four study conditions that were implemented. Nearly 65% of the letters (124 of 192 were returned. We found: 1 letters addressed to a fictitious Institute of Chiropractic Care were just as likely to be returned as those addressed to a fictitious Institute of Medicine; 2 letters with female return addresses were as likely to be returned as those with male return addresses; 3 there was no interaction between study conditions; 4 based on what was essentially a replication study, a comparison of the pattern of returns using the first and second cycle of lost letters (n = 96 for each cycle revealed an equivalent pattern of no-difference findings. DOI: 10.2458/azu_jmmss.v1i1.78

  3. DOE Advanced Scientific Advisory Committee (ASCAC): Workforce Subcommittee Letter

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, Barbara [University of Houston; Calandra, Henri [Total SA; Crivelli, Silvia [Lawrence Berkeley National Laboratory, University of California, Davis; Dongarra, Jack [University of Tennessee; Hittinger, Jeffrey [Lawrence Livermore National Laboratory; Lathrop, Scott A. [NCSA, University of Illinois Urbana-Champaign; Sarkar, Vivek [Rice University; Stahlberg, Eric [Advanced Biomedical Computing Center; Vetter, Jeffrey S. [Oak Ridge National Laboratory; Williams, Dean [Lawrence Livermore National Laboratory

    2014-07-23

    Simulation and computing are essential to much of the research conducted at the DOE national laboratories. Experts in the ASCR ¬relevant Computing Sciences, which encompass a range of disciplines including Computer Science, Applied Mathematics, Statistics and domain Computational Sciences, are an essential element of the workforce in nearly all of the DOE national laboratories. This report seeks to identify the gaps and challenges facing DOE with respect to this workforce. This letter is ASCAC’s response to the charge of February 19, 2014 to identify disciplines in which significantly greater emphasis in workforce training at the graduate or postdoctoral levels is necessary to address workforce gaps in current and future Office of Science mission needs.

  4. Concepts of a quantum information theory of many letters

    CERN Document Server

    Boström, K J

    2000-01-01

    A theoretical framework is presented allowing the treatment of quantum messages with components of variable length. To this aim a many-letter space is constructed which turns out to be a natural space for quantum messages of this type, generalizing the usual fixed-length quantum information theory which is fully contained within this framework. An observable is defined measuring the amount of quantum information carried by a particular message, with the "qbit" obtaining a second meaning as its unit. A general characterization of quantum codes is given where compression codes are defined by their property of decreasing the average information content of a given a priori message ensemble. A lossless quantum coding scheme - analog to the classical Huffman scheme but different from the Braunstein scheme - is implemented, which not only ensures perfect fidelity in retrieving the original messages but also provides optimal compression.

  5. Lossless quantum coding in many-letter spaces

    CERN Document Server

    Boström, K J

    2000-01-01

    Based on the concept of many-letter theory a general characterization of quantum codes using the Kraus representation is given. Compression codes are defined by their property of decreasing the average information content of a given a priori message ensemble. Lossless quantum codes, in contrast to lossy codes, provide the retrieval of the original input states with perfect fidelity. A general lossless coding scheme is given that translates between two quantum alphabets. It is shown that this scheme is never compressive. Furthermore, a lossless quantum coding scheme, analog to the classical Huffman scheme but different from the Braunstein scheme, is implemented, which provides optimal compression. Motivated by the concept of lossless quantum compression, an observable is defined that measures the amount of compressible quantum information contained in a particular message with respect to a given \\emph{a priori} message ensemble. The average of this observable yields the von Neumann entropy, which is finally es...

  6. A Thematic Analysis of Hawthorne's The Scarlet Letter

    Directory of Open Access Journals (Sweden)

    Pyeaam Abbasi

    2009-01-01

    Full Text Available The Scarlet Letter is yet another story of the never-ending conflict of individuals versus society in which the recurrent theme of appearance versus reality is central and woven into different elements of the novel. The significance of this theme lies in the fact that it is adopted by both the Puritan Culture to subjugate its members and hide the truth, and by a protagonist who claims a new identity and violates the Puritanical codes. This is traceable in two major binary oppositions elaborated in this paper as: Society / Individual; and Religion / Love with a look at the two characters of Dimmesdale / Hester and the two colours of Sable / Gules. This paper is an attempt to show how these binary oppositions work, throughout the novel, to stress appearance as a tool for fixing Puritanical codes, and reality as a tool for constructing new ones.

  7. Reply to the Letter by Gary C. Vezzoli

    Directory of Open Access Journals (Sweden)

    Shnoll S. E.

    2008-04-01

    Full Text Available In a letter published by Dr. Vezzoli in the current issue of your journal, he claims priority back to 2001 for an explanation to certain gravitational phenomena, which were first recorded by me and my co-workers at my laboratory. He claims priority to me on the basis of the fact that he shared his results and plans with me in 2001 in private communication. However, I and my co-workers understood the phenomena in the same terms as much as 20 years before that, in the 1980's, and discussed by us in numerous publications during the 1980's, in the Soviet (now Russian scientific journals. I provide a list of my early publications, refuting Dr. Vezzoli's claim to priority.

  8. Reply to the Letter by Gary C. Vezzoli

    Directory of Open Access Journals (Sweden)

    Shnoll S. E.

    2008-04-01

    Full Text Available In a letter published by Dr. Vezzoli in the current issue of your journal, he claims priority back to 2001 for an explanation to certain gravitational phenomena, which were first recorded by me and my co-workers at my laboratory. He claims priority to me on the basis of the fact that he shared his results and plans with me in 2001 in private communication. However, I and my co-workers understood the phenomena in the same terms as much as 20 years before that, in the 1980’s, and discussed by us in numerous publications during the 1980’s, in the Soviet (now Russian scientific journals. I provide a list of my early publications, refuting Dr. Vezzoli’s claim to priority.

  9. Why are digits easier to identify than letters?

    Science.gov (United States)

    Schubert, Teresa M

    2017-01-27

    Beginning with Dejerine's report of pure alexia in 1892, numerous researchers have noted that individuals with acquired impairments of reading may show spared digit identification performance. This digit advantage has also been found in unimpaired adult readers across a number of tasks, and five main hypotheses have been proposed to explain how it arises. In this paper I consider these hypotheses in the context of recent theories of a unified alphanumeric character identification system, and evaluate them according to relevant empirical evidence. Despite some promising findings, none of the hypotheses currently provide a sufficient explanation of the digit advantage. Rather than developing new hypotheses to explain a categorical difference between digit and letter performance, I argue that future work should consider factors that affect identification performance specific to individual characters.

  10. MARGINALIA TO BIRCHBARK LETTERS AND SOME OLD RUSSIAN EPIGRAPHIC TEXTS

    Directory of Open Access Journals (Sweden)

    Marina A. Bobrik

    2014-01-01

    Full Text Available This series of notes deals with several lexical (bebrъkъ ‘young beaver’, ryti rěku ‘to change the course of a river by digging a channel’, na časy ‘in time’, grammatical (object case variation in the name lists to commemorate during the liturgy and phonetic (pronunciation of tense consonants reflected in writing phenomena in birch bark letters (№ 7, 59, 445, 506, 508а, 508б, 522, 541, 542, 551, 559, 560, 561, 595, 765 and in two Old Russian inscriptions — on the Sterzhen Cross (1133 A.D. and in the Church of Sts. Boris and Gleb in Novogrudok (12th c.. Some refinements to prior interpretations are proposed, and, in addition, some novel solutions. 

  11. Science Letters: Efficient page layout analysis on small devices

    Institute of Scientific and Technical Information of China (English)

    Eun-jung HAN; Chee-onn WONG; Kee-chul JUNG; Kyung-ho LEE; Eun-yi KIM

    2009-01-01

    Previously we have designed and implemented new image browsing facilities to support effective offline image contents on mobile devices with limited capabilities: low bandwidth, small display, and slow processing. In this letter, we fulfill the automatic production of cartoon contents fitting small-screen display, and introduce a clustering method useful for various types of cartoon images as a prerequisite stage for preserving semantic meaning. The usage of neural networks is to properly cut the various forms of pages. Texture information that is useful for grayscale image segmentation gives us a good clue for page layout analysis using the multilayer perceptron (MLP) based x-y recursive algorithm. We also automatically frame the segment MLP using agglomerative segmentation. Our experimental results show that the combined approaches yield good results of segmentation for several cartoons.

  12. Tank waste source term inventory validation. Volume 1. Letter report

    Energy Technology Data Exchange (ETDEWEB)

    Brevick, C.H.; Gaddis, L.A.; Johnson, E.D.

    1995-04-28

    The sample data for selection of 11 radionuclides and 24 chemical analytes were extracted from six separate sample data sets, were arranged in a tabular format and were plotted on scatter plots for all of the 149 single-shell tanks, the 24 double-shell tanks and the four aging waste tanks. The solid and liquid sample data was placed in separate tables and plots. The sample data and plots were compiled from the following data sets: characterization raw sample data, recent core samples, D. Braun data base, Wastren (Van Vleet) data base, TRAC and HTCE inventories. This document is Volume I of the Letter Report entitled Tank Waste Source Term Inventory Validation.

  13. Modern physics letters A special issue on hadrontherapy

    CERN Document Server

    2015-01-01

    CERN Courier Review (Jul 8, 2016) : The applications of nuclear and particle physics to medicine have seen extraordinary development since the discovery of X-rays by Röntgen at the end of the 19th century. Medical imaging and oncologic therapy with photons and charged particles (specifically hadrons) are currently hot research topics. This special issue of Modern Physics Letters is dedicated to hadron therapy, which is the frontier of cancer radiation therapy, and aims at filling a gap in the current literature on medical physics. Through 10 invited review papers, the volume presents the basics of hadron therapy, along with the most recent scientific and technological developments in the field. The first part covers topics such as the history of hadron therapy, radiation biophysics, particle accelerators, dose-delivery systems and treatment planning. In the second part, more specific topics are treated, including dose and beam monitoring, proton computer tomography, innoacustics and microdosimetry. This vo...

  14. Authors' response to the letter from Kalleian Eserian et al.

    Science.gov (United States)

    van Riet-Nales, Diana A; Doeve, Myrthe E; Nicia, Agnes E; Teerenstra, Steven; Notenboom, Kim; Hekster, Yechiel A; van den Bemt, Bart J F

    2015-01-30

    This letter is a response to the comments of Kalleian Eserian et al. on our study relating to the accuracy, precision and sustainability of six tablet splitters and a kitchen knife as an alternative to breaking paracetamol 500mg tablets by hand. We would like to inform the readers of International Journal of Pharmaceutics that our study focused on splitting tablets with a mechanical tool rather than breaking tablets by hand. Although publications on hand breaking tablets were not cited for this reason, we are familiar with the conclusions of these publications. This is especially true for the publications that were written by direct colleagues from the department of the corresponding author e.g., Van Santen et al. and Van der Steen et al.

  15. Multiple Levels of Letter Representation in Written Spelling: Evidence From a Single Case of Dysgraphia with Multiple Deficits

    Directory of Open Access Journals (Sweden)

    Marie-Pierre de Partz

    2005-01-01

    Full Text Available In this paper, we report a detailed analysis of the impaired performance of a dysgraphic individual, AD, who produced similar rates of letter-level errors in written spelling, oral spelling, and typing. We found that the distribution of various letter error types displayed a distinct pattern in written spelling on the one hand and in oral spelling and typing on the other. In particular, noncontextual letter substitution errors (i.e., errors in which the erroneous letter that replaces the target letter does not occur elsewhere within the word were virtually absent in oral spelling and typing and mainly found in written spelling. In contrast, letter deletion errors and multiple-letter errors were typically found in oral spelling and very exceptional in written spelling. Only contextual letter substitution errors (i.e., errors in which the erroneous letter that replaces the target letter is identical to a letter occurring earlier or later in the word were found in similar proportions in the three tasks. We argue that these contrasting patterns of letter error distribution result from damage to two distinct levels of letter representation and processing within the spelling system, namely, the amodal graphemic representation held in the graphemic buffer and the letter form representation computed by subsequent writing-specific processes. Then, we examined the relationship between error and target in the letter substitution errors produced in written and oral spelling and found evidence that distinct types of letter representation are processed at each of the hypothetized levels of damage: symbolic letter representation at the graphemic level and representation of the component graphic strokes at the letter form processing level.

  16. Perceptual learning: tactile letter recognition transfers across body surfaces.

    Science.gov (United States)

    Arnold, Gabriel; Auvray, Malika

    2014-01-01

    Visual-to-tactile sensory substitution devices are designed to assist visually impaired people by converting visual stimuli into tactile stimuli. The important claim has been made that, after training with these devices, the tactile stimuli can be moved from one body surface to another without any decrease in performance. This claim, although recurrent, has never been empirically investigated. Moreover, studies in the field of tactile perceptual learning suggest that performance improvement transfers only to body surfaces that are closely represented in the somatosensory cortex, i.e. adjacent or homologous contralateral body surfaces. These studies have however mainly used discrimination tasks of stimuli varying along only one feature (e.g., orientation of gratings) whereas, in sensory substitution, tactile information consists of more complex stimuli. The present study investigated the extent to which there is a transfer of tactile letter learning. Participants first underwent a baseline session in which the letters were presented on their belly, thigh, and shin. They were subsequently trained on only one of these body surfaces, and then re-tested on all of them, as a post-training session. The results revealed that performance improvement was the same for both the trained and the untrained surfaces. Moreover, this transfer of perceptual learning was equivalent for adjacent and non-adjacent body surfaces, suggesting that tactile learning transfer occurs independently of the distance on the body. A control study consisting of the same baseline and post-training sessions, without training in between, revealed weaker improvement between the two sessions. The obtained results support the claim that training with sensory substitution devices results in a relative independence from the stimulated body surface.

  17. The locus of impairment in English developmental letter position dyslexia

    Directory of Open Access Journals (Sweden)

    Yvette eKezilas

    2014-06-01

    Full Text Available Many children with reading difficulties display phonological deficits and struggle to acquire nonlexical reading skills. However, not all children with reading difficulties have these problems, such as children with selective Letter Position Dyslexia (LPD, who make excessive migration errors (such as reading slime as ‘smile’. Previous research has explored three possible loci for the deficit – the phonological output buffer, the orthographic input lexicon, and the orthographic-visual analysis stage of reading. While there is compelling evidence against a phonological output buffer and orthographic input lexicon deficit account of English LPD, the evidence in support of an orthographic-visual analysis deficit is currently limited. In this multiple single-case study with three English speaking children with developmental LPD we aimed to both replicate and extend previous findings regarding the locus of impairment in English LPD. First, we ruled out a phonological output buffer and an orthographic input lexicon deficit by administering tasks that directly assess phonological processing and lexical guessing. We then went on to directly assess whether or not children with LPD have an orthographic-visual analysis deficit by modifying two tasks that have previously been used to localize processing at this level: a same-different decision task and a nonword reading task. The results from these tasks indicate that LPD is most likely caused by a deficit specific to the coding of letter positions at the orthographic-visual analysis stage of reading. These findings provide further evidence for the heterogeneity of dyslexia and its underlying causes.

  18. The locus of impairment in English developmental letter position dyslexia.

    Science.gov (United States)

    Kezilas, Yvette; Kohnen, Saskia; McKague, Meredith; Castles, Anne

    2014-01-01

    Many children with reading difficulties display phonological deficits and struggle to acquire non-lexical reading skills. However, not all children with reading difficulties have these problems, such as children with selective letter position dyslexia (LPD), who make excessive migration errors (such as reading slime as "smile"). Previous research has explored three possible loci for the deficit - the phonological output buffer, the orthographic input lexicon, and the orthographic-visual analysis stage of reading. While there is compelling evidence against a phonological output buffer and orthographic input lexicon deficit account of English LPD, the evidence in support of an orthographic-visual analysis deficit is currently limited. In this multiple single-case study with three English-speaking children with developmental LPD, we aimed to both replicate and extend previous findings regarding the locus of impairment in English LPD. First, we ruled out a phonological output buffer and an orthographic input lexicon deficit by administering tasks that directly assess phonological processing and lexical guessing. We then went on to directly assess whether or not children with LPD have an orthographic-visual analysis deficit by modifying two tasks that have previously been used to localize processing at this level: a same-different decision task and a non-word reading task. The results from these tasks indicate that LPD is most likely caused by a deficit specific to the coding of letter positions at the orthographic-visual analysis stage of reading. These findings provide further evidence for the heterogeneity of dyslexia and its underlying causes.

  19. A very large soul: selected letters from Margaret Laurence to Canadian writers A very large soul: selected letters from Margaret Laurence to Canadian writers

    Directory of Open Access Journals (Sweden)

    John J. O'Connor

    2008-04-01

    Full Text Available “This will be a brief letter, as I have a horrifying stack of business letters to catch up on,” wrote Margaret Laurence to her friend and fellow novelist Gabrielle Roy in 1978, echoing an earlier lament to her epistolary friend Ernest Buckler about the need to “keep pace with the ghastly flow of business correspondence.” Although she was always to face some tension between her personal and professional selves as correspondent, her priority was never in question: “Must go. I have 70 letters to reply to, having got far behind in correspondence ... am trying now to communicate once again with dear friends first, and then to answer all the others, which will no doubt be my winter project” (4 Sept. 1974 letter to Silver Donald Cameron. “This will be a brief letter, as I have a horrifying stack of business letters to catch up on,” wrote Margaret Laurence to her friend and fellow novelist Gabrielle Roy in 1978, echoing an earlier lament to her epistolary friend Ernest Buckler about the need to “keep pace with the ghastly flow of business correspondence.” Although she was always to face some tension between her personal and professional selves as correspondent, her priority was never in question: “Must go. I have 70 letters to reply to, having got far behind in correspondence ... am trying now to communicate once again with dear friends first, and then to answer all the others, which will no doubt be my winter project” (4 Sept. 1974 letter to Silver Donald Cameron.

  20. The Barthel index-dyspnea a tool for respiratory rehabilitation: reply to the letter by Chuang [Letter of clarification

    Directory of Open Access Journals (Sweden)

    Carone M

    2017-03-01

    Full Text Available Mauro Carone,1 Michele Vitacca,2 Mara Paneroni,2 Paola Baiardi,3 Antonio Spanevello,4,5 Giorgio Bertolotti6 1Respiratory Division, ICS MAUGERI SPA SB, Institute of Cassano Murge (BA IRCCS, Italy; 2Respiratory Rehabilitation Division, ICS MAUGERI SPA SB, Institute of Lumezzane (BS IRCCS, Italy; 3Scientific Direction, ICS MAUGERI SPA SB, Institute of Pavia, IRCCS, Italy; 4Respiratory Rehabilitation Division, ICS MAUGERI SPA SB, Institute of Tradate (VA IRCCS, Italy; 5Respiratory Diseases Unit, University of Insubria, Varese; 6Psychology Unit, ICS MAUGERI SPA SB, Institute of Tradate (VA IRCCS, Italy We read the remarkable letter by Chuang.1 We thank him for his valid suggestions on our paper. Interestingly, he focused on the two dimensions of the Barthel index-dyspnea (BI-d, which was exactly our goal. As rehabilitators, our goal is to provide patients with physical therapy depending on their health status and to improve their respiratory function. We need to verify and demonstrate the efficacy and the outcomes of respiratory rehabilitation, supported by physical therapy. For these reasons, we need an assessment device that measures respiratory improvement during daily motor activities that should be monitored.The modified Barthel index2 is a well-consolidated and widely used instrument to assess the performance of a person in a predetermined and fixed set of activities of daily living (ADLs. By proposing BI-d,3 we aimed to develop a scale to measure how dyspnea precludes or reduces the same ADLs, with the ultimate goal of globally assessing the effectiveness of rehabilitation. Hence, an assessment method that measures the impact of dyspnea on activities monitored by a rehabilitation program is of utmost importance for rehabilitators. Large part of Chuang’s letter is based on the Chronic Respiratory Questionnaire-dyspnea (CRQ-d. The CRQ-d is a health-related quality of life (health status questionnaire, with a dyspnea “domain”.4 However

  1. 32 CFR 552.77 - Suspension approval.

    Science.gov (United States)

    2010-07-01

    ... 32 National Defense 3 2010-07-01 2010-07-01 true Suspension approval. 552.77 Section 552.77 National Defense Department of Defense (Continued) DEPARTMENT OF THE ARMY MILITARY RESERVATIONS AND....77 Suspension approval. The installation commander will personally approve all cases in...

  2. 40 CFR 123.61 - Approval process.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 21 2010-07-01 2010-07-01 false Approval process. 123.61 Section 123... REQUIREMENTS Program Approval, Revision, and Withdrawal § 123.61 Approval process. (a) After determining that a...; and (6) Briefly outline the fundamental aspects of the State's proposed program, and the process...

  3. 40 CFR 145.31 - Approval process.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 22 2010-07-01 2010-07-01 false Approval process. 145.31 Section 145.31 Protection of Environment ENVIRONMENTAL PROTECTION AGENCY (CONTINUED) WATER PROGRAMS (CONTINUED) STATE UIC PROGRAM REQUIREMENTS Program Approval, Revision and Withdrawal § 145.31 Approval process....

  4. 12 CFR 611.510 - Approval procedures.

    Science.gov (United States)

    2010-01-01

    ... 12 Banks and Banking 6 2010-01-01 2010-01-01 false Approval procedures. 611.510 Section 611.510 Banks and Banking FARM CREDIT ADMINISTRATION FARM CREDIT SYSTEM ORGANIZATION Transfer of Authorities § 611.510 Approval procedures. (a) Upon receipt of approval of a resolution by the Farm...

  5. 76 FR 60357 - Federal Regulations; OMB Circulars, OFPP Policy Letters, and CASB Cost Accounting Standards...

    Science.gov (United States)

    2011-09-29

    ... derived from 41 U.S.C. 1501. Cost Accounting Standards are rules governing the measurement, assignment... and 48 CFR Ch. 1 Federal Regulations; OMB Circulars, OFPP Policy Letters, and CASB Cost Accounting... Procurement Policy (OFPP) Policy Letters, and Cost Accounting Standards Board (CASB) Cost Accounting...

  6. 76 FR 14407 - Exchange of Letters Between Dr. Murray M. Lumpkin, Deputy Commissioner, International Programs...

    Science.gov (United States)

    2011-03-16

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF HEALTH AND HUMAN SERVICES Food and Drug Administration Exchange of Letters Between Dr. Murray M. Lumpkin, Deputy... providing notice of exchange of letters between Dr. Murray M. Lumpkin, Deputy Commissioner,...

  7. 44 CFR 70.7 - Notice of Letter of Map Amendment.

    Science.gov (United States)

    2010-10-01

    ... 44 Emergency Management and Assistance 1 2010-10-01 2010-10-01 false Notice of Letter of Map Amendment. 70.7 Section 70.7 Emergency Management and Assistance FEDERAL EMERGENCY MANAGEMENT AGENCY... Notice of Letter of Map Amendment. (a) The Federal Insurance Administrator, shall not publish a notice...

  8. Neural Dissociation of Number from Letter Recognition and Its Relationship to Parietal Numerical Processing

    Science.gov (United States)

    Park, Joonkoo; Hebrank, Andrew; Polk, Thad A.; Park, Denise C.

    2012-01-01

    The visual recognition of letters dissociates from the recognition of numbers at both the behavioral and neural level. In this article, using fMRI, we investigate whether the visual recognition of numbers dissociates from letters, thereby establishing a double dissociation. In Experiment 1, participants viewed strings of consonants and Arabic…

  9. 32 CFR Appendix B to Part 216 - ROTC Sample Letter of Inquiry

    Science.gov (United States)

    2010-07-01

    ... INSTITUTIONS OF HIGHER EDUCATION Pt. 216, App. B Appendix B to Part 216—ROTC Sample Letter of Inquiry (Tailor letter to situation presented) Dr. Jane Smith, President, ABC University, Anywhere, USA 12345-9876. Dear... institution of higher education, or to an individual, to be available solely for student financial...

  10. Letters From the Public: A Portrait of Popular Astronomy in Mexico (1918-1947)

    Science.gov (United States)

    Biro, S.

    2011-10-01

    The letters that Joaquín Gallo received while he was director of the National Astronomical Observatory (OAN) allow us glimpses of astronomy in Mexican popular culture in the first half of the 20th century. An examination of the interests and motivations of the authors of these letters produces a portrait of the Mexicans interested in astronomy.

  11. Electrical Connections: Letters to Thomas Edison in Response to His Claim of Solving Incandescent Lighting, 1878.

    Science.gov (United States)

    Bazerman, Charles

    1994-01-01

    Discusses the way in which letters sent to Thomas Edison following the report that he had solved the problem of incandescent lighting reveal the many discursive worlds that Edison's work touched. Claims these letters indicate how a technological accomplishment is also a multiple, complex social, and communicative accomplishment, creating place and…

  12. Writing Cover Letters That Address Instructor Feedback Improves Final Papers in a Research Methods Course

    Science.gov (United States)

    Daniel, Frances; Gaze, Catherine M.; Braasch, Jason L. G.

    2015-01-01

    We examined how writing cover letters to the instructor influenced final papers in research methods courses. After receiving instructor feedback on drafts of each section of an American Psychological Association style research paper throughout the semester, students in two classes wrote cover letters to the instructor explaining how the instructor…

  13. Resource Letter TTSM-1: Teaching thermodynamics and statistical mechanics in introductory physics, chemistry, and biology

    CERN Document Server

    Dreyfus, Benjamin W; Meltzer, David E; Sawtelle, Vashti

    2014-01-01

    This Resource Letter draws on discipline-based education research from physics, chemistry, and biology to collect literature on the teaching of thermodynamics and statistical mechanics in the three disciplines. While the overlap among the disciplinary literatures is limited at present, we hope this Resource Letter will spark more interdisciplinary interaction.

  14. The New Scarlet Letter: Student Perceptions of the Accounting Profession after Enron

    Science.gov (United States)

    Coleman, Mimi; Kreuze, Jerry; Langsam, Sheldon

    2004-01-01

    Recent scandals have tarnished the integrity of the accounting profession, marking it with a modern version of the scarlet letter "A," which represented disgrace in Nathaniel Hawthorne's "The Scarlet Letter." In this study, the authors surveyed college business students on their perceptions of the accounting profession and examined how it can…

  15. 19 CFR 181.100 - Effect of NAFTA advance ruling letters; modification and revocation.

    Science.gov (United States)

    2010-04-01

    ... ruling letter, either directly, by reference, or by implication, is accurate and complete in every... to which it is purported to relate is subject to the verification of the facts incorporated in the...) Regional value content rulings. Each advance ruling letter concerning the application of a regional...

  16. Effect on Mail Survey Return Rates of Including Questionnaires With Follow-Up Letters.

    Science.gov (United States)

    Futrell, Charles M.; Lamb, Charles W., Jr.

    1981-01-01

    Two thousand questionnaires were mailed to respondents allocated among seven treatments. Controls received an initial mailing (questionnaire and cover letter) only. The remaining six treatments varied by number of follow-up mailings and whether another questionnaire copy was included. Results suggest more than one follow-up letter with a…

  17. A drift towards direct structures in Dutch direct mail sales letters

    NARCIS (Netherlands)

    Jansen, Frank; Stukker, Ninne

    2014-01-01

    Dutch direct mail sales letters have traditionally had an indirect structure. In such a format, the transactional proposition is presented late in the letter in order to maximize the possibility that the readers will pay attention to, be interested in, and feel motivated to consider the proposition

  18. Managing Dissent in the Catholic Church: A Reinterpretation of the Pastoral Letter on War and Peace.

    Science.gov (United States)

    Hogan, J. Michael

    1989-01-01

    Reexamines the American National Conference of Catholic Bishops' 1983 Pastoral Letter on War and Peace. Finds that the pastoral letter functioned rhetorically not to foster but to manage dissent, diffusing a radical Catholic challenge to American defense policy and reclaiming the bishops' authority to define Church teachings on war and peace. (SR)

  19. The Letter Position as Facilitative or Debilitative in Word Retention of EFL Learners

    Science.gov (United States)

    Marefat, Hamideh; Shirazi, Masoumeh Ahmadi

    2014-01-01

    This study concerns the effect of letter position on the retention of words by EFL learners. Given the fact that everyone has a mental lexicon, we would suggest that words are possibly organized in alphabetical order, then it would be likely for the learners to retain the words easily when exposed to the first letters of given words. The study…

  20. An Analysis of English Business Letters from the Perspective of Interpersonal Function

    Science.gov (United States)

    Xu, Bo

    2012-01-01

    The purpose of the present study is to find out the features of English business letters. Halliday's systemic functional linguistics is used as the theoretical framework, mainly, interpersonal fucntion. The English business letter (EBL) is an important written text used for international business communication and it has its own features of text.…

  1. Adolescent Sexual Initiation through the Lens of Letters to the Editor Published in Polish Teenage Magazines

    Science.gov (United States)

    Kopacz, Marek S.; Bajka-Kopacz, Aleksandra

    2012-01-01

    Almost all teenage magazines invite readers to submit questions concerning relationships, published as letters to the editor, popularly called "advice columns," often containing explicit questions about sexuality. This study aims to examine, firstly, how themes related to sexual initiation are presented in letters to the editor published…

  2. Exploiting a Corpus of Business Letters from a Phraseological, Functional Perspective

    Science.gov (United States)

    Flowerdew, Lynne

    2012-01-01

    This paper illustrates how a freely available online corpus has been exploited in a module on teaching business letters covering the following four speech acts (functions) commonly found in business letters: invitations, requests, complaints and refusals. It is proposed that different strategies are required for teaching potentially…

  3. The Presentation of Self in Letters of Application: A Mixed-Method Approach

    Science.gov (United States)

    Soroko, Emilia

    2012-01-01

    The application letter, as the first phase of employment-seeking, is an opportunity for a job applicant to make a favorable impression on a potential employer. In the current study, the author used a mixed-method approach to empirically explore strategies for self-presentation in job application letters and determine the methods used in the…

  4. The Long Road to Automation: Neurocognitive Development of Letter-Speech Sound Processing

    Science.gov (United States)

    Froyen, Dries J. W.; Bonte, Milene L.; van Atteveldt, Nienke; Blomert, Leo

    2009-01-01

    In transparent alphabetic languages, the expected standard for complete acquisition of letter-speech sound associations is within one year of reading instruction. The neural mechanisms underlying the acquisition of letter-speech sound associations have, however, hardly been investigated. The present article describes an ERP study with beginner and…

  5. Harvard Education Letter. Volume 27, Number 2, March-April 2011

    Science.gov (United States)

    Walser, Nancy, Ed.

    2011-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Hybrid Schools for the iGeneration: New Schools Combine "Bricks" and "Clicks" (Brigid Schulte); (2) Dual Language Programs on the Rise: "Enrichment" Model Puts Content Learning…

  6. Harvard Education Letter. Volume 24, Number 4, July-August 2008

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2008-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Taking the Measure of New Teachers: California Shifts from Standardized Tests to Performance-Based Assessment as a Condition of Licensure (Robert Rothman); (2) When 1/2 + 1/3 =…

  7. Harvard Education Letter. Volume 22, Number 3, May-June 2006

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2006-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Making Schools Safer for LGBT Youth: Despite Signs of Progress, Lesbian, Gay, Bisexual, and Transgender Students Say Harassment Persists (Michael Sadowski); (2) Rx for a…

  8. Harvard Education Letter. Volume 23, Number 5, September-October 2007

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2007-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Confronting the Autism Epidemic: New Expectations for Children with Autism Means a New Role for Public Schools (Kate McKenna); (2) Internet Research 101: How to Help Middle…

  9. Harvard Education Letter. Volume 25, Number 2, March-April 2009

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2009-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Money and Motivation: New Initiatives Rekindle Debate over the Link between Rewards and Student Achievement (David McKay Wilson); (2) An Inexact Science: What Are the Technical…

  10. Harvard Education Letter. Volume 23, Number 4, July-August 2007

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2007-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Meeting of the Minds: The Parent-Teacher Conference Is the Cornerstone of School-Home Relations. How Can It Work for All Families? (Laura Pappano); (2) In Search of That "Third…

  11. Harvard Education Letter. Volume 25, Number 1, January-February 2009

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2009-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Learning Across Distance: Virtual-Instruction Programs Are Growing Rapidly, but the Impact on "Brick-and-Mortar" Classrooms Is Still up in the Air…

  12. Harvard Education Letter. Volume 24, Number 3, May-June 2008

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2008-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) "Equity, Access, and Opportunity": Despite Challenges, More Districts Adopt One-to-One Laptop Programs (Colleen Gillard); (2) Small Kids, Big Words: Research-Based Strategies…

  13. Harvard Education Letter. Volume 24, Number 2, March-April 2008

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2008-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Educating Teenage Immigrants: High Schools Experiment with Ways to Group New English-Language Learners (Lucy Hood); (2) Hot Topics and Key Words: Pilot Project Brings Teachers…

  14. Harvard Education Letter. Volume 25, Number 5, September-October 2009

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2009-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) The Invisible Hand in Education Policy: Behind the Scenes, Economists Wield Unprecedented Influence (David McKay Wilson); (2) Bonding and Bridging: Schools Open Doors for…

  15. Harvard Education Letter. Volume 24, Number 1, January-February 2008

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2008-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Leadership Lessons From Schools Becoming "Data Wise" (Jennifer L. Steele and Kathryn Parker Boudett); (2) A Guide on the Side: Mentors Help New Leaders Prepare for Life in the…

  16. Harvard Education Letter. Volume 28, Number 1, January-February 2012

    Science.gov (United States)

    Walser, Nancy, Ed.

    2012-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Using Theater to Teach Social Skills: Researchers Document Improvements for Children with Autism (Patti Hartigan); (2) The Family Model of Schooling Revisited: Few Teachers,…

  17. Harvard Education Letter. Volume 27, Number 3, May-June 2011

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2011-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Bringing Art into School, Byte by Byte: Innovative Programs Use Technology to Expand Access to the Arts (Patti Hartigan); (2) Differentiated Instruction…

  18. Harvard Education Letter. Volume 23, Number 3, May-June 2007

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2007-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) The Road to School Improvement: It's Hard, It's Bumpy, and It Takes as Long as It Takes (Richard F. Elmore and Elizabeth A. City); (2) Better Teaching with Web Tools: How…

  19. Harvard Education Letter. Volume 27, Number 1, January-February 2011

    Science.gov (United States)

    Walser, Caroline T., Ed.

    2011-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) The Greening of Environmental Ed: Teachers Focus on Complexity, Evidence, and Letting Students Draw Their Own Conclusions (Lucy Hood); (2) Like Teacher,…

  20. Harvard Education Letter. Volume 22, Number 1, January-February 2006

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2006-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) The "Data Wise" Improvement Process: Eight Steps for Using Test Data to Improve Teaching and Learning (Kathryn Parker Boudett, Elizabeth A. City,…

  1. Harvard Education Letter. Volume 26, Number 1, January-February 2010

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2010-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Charters and Unions: What's the Future for This Unorthodox Relationship? (Alexander Russo); (2) From Special Ed to Higher Ed: Transition Planning for Disabled Students Focuses…

  2. Harvard Education Letter. Volume 22, Number 6, November-December 2006

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2006-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) (In)formative Assessments: New Tests and Activities Can Help Teachers Guide Student Learning (Robert Rothman); (2) Recent Research on the Achievement Gap: How Lifestyle…

  3. Harvard Education Letter. Volume 24, Number 5, September-October 2008

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2008-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Teaching 21st Century Skills: What Does It Look Like in Practice? (Nancy Walser); (2) Getting and Spending: Schools and Districts Share Lessons on the Effective Uses of…

  4. Harvard Education Letter. Volume 22, Number 4, July-August 2006

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2006-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Beyond Auto Shop 1: Is Career and Technical Education a Promising Path for High School Reform? (Lucy Hood); (2) The School Readiness Gap:…

  5. Harvard Education Letter. Volume 27, Number 6, November-December 2011

    Science.gov (United States)

    Walser, Nancy, Ed.

    2011-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) With Cheating on the Rise, Schools Respond (David McKay Wilson); (2) Waldorf Education in Public Schools: Educators Adopt--and Adapt--This Developmental, Arts-Rich Approach…

  6. Harvard Education Letter. Volume 26, Number 4, July-August 2010

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2010-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Learning Progressions in Science: A New Approach Emphasizes Sustained Instruction in Big Ideas (Patti Hartigan); (2) Putting the "Boy Crisis" in…

  7. Harvard Education Letter. Volume 23, Number 1, January-February 2007

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2007-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Response to Intervention: A New Approach to Reading Instruction Aims to Catch Struggling Readers Early (Nancy Walser); (2) Getting Advisory Right: Focus and…

  8. Harvard Education Letter. Volume 24, Number 6, November-December 2008

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2008-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) When Worlds Collide: Universal PreK Brings New Challenges for Public Elementary Schools (David McKay Wilson); (2) Answers and Questions: Schools Survey Their Students--and…

  9. Harvard Education Letter. Volume 25, Number 3, May-June 2009

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2009-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Improving Teaching and Learning through Instructional Rounds (Lee Teitel); (2) Developmentally Appropriate Practice in the Age of Testing: New Reports Outline Key Principles…

  10. Harvard Education Letter. Volume 26, Number 2, March-April 2010

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2010-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Online Testing, Version 1.0: Oregon's Adaptive Computer-Based Accountability Test Offers a Peek at a Brave New Future (Robert Rothman); (2) Beyond…

  11. Harvard Education Letter. Volume 22, Number 3, May-June 2006

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2006-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Making Schools Safer for LGBT Youth: Despite Signs of Progress, Lesbian, Gay, Bisexual, and Transgender Students Say Harassment Persists (Michael Sadowski);…

  12. Harvard Education Letter. Volume 26, Number 3, May-June 2010

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2010-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Unleashing the "Brain Power" of Groups in the Classroom: The Neuroscience behind Collaborative Work (Nancy Walser); (2) Putting AP to the Test: New Research Assesses the…

  13. Harvard Education Letter. Volume 27, Number 5, September-October 2011

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2011-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Teaching Students to Ask Their Own Questions: One Small Change Can Yield Big Results (Dan Rothstein and Luz Santana); (2) Voice of Experience: Jerry Weast--Leading a System…

  14. Harvard Education Letter. Volume 23, Number 2, March-April 2007

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2007-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) More Than "Making Nice": Getting Teachers to (Truly) Collaborate (Laura Pappano); (2) "Doing the Critical Things First": An Aligned Approach to PreK and Early Elementary Math;…

  15. Harvard Education Letter. Volume 23, Number 6, November-December 2007

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2007-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Charting a New Course toward Racial Integration: Districts Seek Legal Routes to Capture the Benefits of Diversity (Brigid Schulte); (2) Voluntary Integration: Two Views--(a)…

  16. Harvard Education Letter. Volume 25, Number 4, July-August 2009

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2009-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Putting the Brakes on "Summer Slide": Modified School Calendars Build in Time to Enrich Learning and Sustain Gains (Brigid Schulte); (2) Closing…

  17. Harvard Education Letter. Volume 26, Number 5, September-October 2010

    Science.gov (United States)

    Walser, Nancy, Ed.

    2010-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Scenes from the School Turnaround Movement: Passion, Frustration, Mid-Course Corrections Mark Rapid Reforms (Laura Pappano); (2) The Media Savvy Educator:…

  18. Harvard Education Letter. Volume 27, Number 4, July-August 2011

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2011-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Integrated Data Systems Link Schools and Communities: Researchers Combine School and Non-School Data to Inform Interventions and Policy (Patti Hartigan);…

  19. Harvard Education Letter. Volume 28, Number 2, March-April 2012

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2012-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Course Credits on the Quick: Controversial Online Recovery Programs Speed the Path to Graduation (Andrew Brownstein); (2) Collaborating to Make Schools More Inclusive…

  20. Harvard Education Letter. Volume 26, Number 6, November-December 2010

    Science.gov (United States)

    Walser, Nancy, Ed.

    2010-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Video Games Take Testing to the Next Level: Researchers See Promise in Game-Like Assessments That Measure Complex Skills (Robert Rothman); (2) An Academic…

  1. Harvard Education Letter. Volume 24, Number 4, July-August 2008

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2008-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Taking the Measure of New Teachers: California Shifts from Standardized Tests to Performance-Based Assessment as a Condition of Licensure (Robert Rothman);…

  2. Harvard Education Letter. Volume 25, Number 6, November-December 2009

    Science.gov (United States)

    Chauncey, Caroline T., Ed.

    2009-01-01

    "Harvard Education Letter" is published bimonthly by the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) "Platooning" Instruction: Districts Weigh Pros and Cons of Departmentalizing Elementary Schools (Lucy Hood); (2) Behind the Classroom Door: A Rare Glimpse Indicates the…

  3. Harvard Education Letter. Volume 22, Number 2, March-April 2006

    Science.gov (United States)

    Chauncey, Caroline, Ed.

    2006-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Talking 'bout Evolution: High School Science Teachers Share Strategies for Dealing with Controversy in the Classroom (Nancy Walser); (2) Standards-Based…

  4. Edmund Burke's "Letter to a Noble Lord": A Textual Study in Political Philosophy and Rhetorical Action.

    Science.gov (United States)

    Browne, Stephen H.

    1988-01-01

    Analyzes Edmund Burke's "Letter to a Noble Lord," noting that it not only reflects Burke's character, but also represents a significant example of the public letter as a rhetorical form and illustrates Burke's concern for the alignment of principle with public action. (MM)

  5. Effect of Assessment Task and Letter Writing Ability on Preschool Children's Spelling Performance

    Science.gov (United States)

    Puranik, Cynthia; Apel, Kenn

    2010-01-01

    The purpose of this study was to examine whether spelling performance in preschool children varied as a function of the method of assessment and letter writing ability. The authors manipulated the motoric element and memory demands of the task by having children spell single words using letter tiles, orally, and by writing. The authors also…

  6. Adolescent Sexual Initiation through the Lens of Letters to the Editor Published in Polish Teenage Magazines

    Science.gov (United States)

    Kopacz, Marek S.; Bajka-Kopacz, Aleksandra

    2012-01-01

    Almost all teenage magazines invite readers to submit questions concerning relationships, published as letters to the editor, popularly called "advice columns," often containing explicit questions about sexuality. This study aims to examine, firstly, how themes related to sexual initiation are presented in letters to the editor published in Polish…

  7. Strategy Effects on Word Searching in Japanese Letter Fluency Tests: Evidence from the NIRS Findings

    Science.gov (United States)

    Hatta, Takeshi; Kanari, Ayano; Mase, Mitsuhito; Nagano, Yuko; Shirataki, Tatsuaki; Hibino, Shinji

    2009-01-01

    Strategy effects on word searching in the Japanese letter fluency test were investigated using the Near-infrared Spectroscopy (NIRS). Participants were given a Japanese letter fluency test and they were classified into two types of strategy users, based on analysis of their recorded verbal responses. One group, AIUEO-order strategy users, employed…

  8. Harvard Education Letter. Volume 20, Number 3, May-June 2004

    Science.gov (United States)

    Sadowski, Michael, Ed.

    2004-01-01

    "Harvard Education Letter" is published bimonthly at the Harvard Graduate School of Education. This issue of "Harvard Education Letter" contains the following articles: (1) Taking Care of Novice Teachers: Researchers Suggest How Administrators Can Keep Their Newer Teachers Teaching and Maintain a First-Rate Faculty (Reino Makkonen); (2) Assessing…

  9. 39 CFR 320.4 - Suspension for certain letters of college and university organizations.

    Science.gov (United States)

    2010-07-01

    ... letters of college and university organizations. The operation of 39 U.S.C. 601(a) (1) through (6) and... university. Colleges and universities choosing to provide their student or faculty organizations access to... of a single college or university and which operate in accordance with the Letters of the...

  10. 49 CFR 220.29 - Statement of letters and numbers in radio communications.

    Science.gov (United States)

    2010-10-01

    ...) FEDERAL RAILROAD ADMINISTRATION, DEPARTMENT OF TRANSPORTATION RAILROAD COMMUNICATIONS Radio and Wireless Communication Procedures § 220.29 Statement of letters and numbers in radio communications. (a) If necessary for... 49 Transportation 4 2010-10-01 2010-10-01 false Statement of letters and numbers in...

  11. The further interpretation of human nature by Hawthorne's novel "the Scarlet Letter"

    Institute of Scientific and Technical Information of China (English)

    Du Feng Wang qingping

    2009-01-01

    "The Scarlet Letter"is Hawthorne's realist representative.In his masterpiece the Scarlet letter,Hawthorne tells us that all human beings are combination of goodness and evil.As hun~n namre changes between goodness and evil,the science mastered by human beings may bring happiness or pains.

  12. Teaching the Pragmatics of Accounts-Payable Letters in Papua New Guinea.

    Science.gov (United States)

    Moody, James

    The development of a course in English letter-writing for workers in the accounts-payable departments of Papua New Guinea businesses is described. The needs assessment involved extensive discussion with company staff and their supervisors, collection and analysis of letters recently produced by that staff, and development of a diagnostic test. It…

  13. Intentional Practices in Supervision of Family Counseling: The Use of Supervisory Letters

    Science.gov (United States)

    Desmond, Kimberly J.; Kindsvatter, Aaron

    2010-01-01

    Supervisors perform various roles in helping to guide the supervisee through the challenging process of family counseling. The use of letters in supervision helps to focus the supervisory processes in family counseling. Following the discrimination model of supervision, three types of supervisory letters are suggested for intentional supervision…

  14. Contributions of Emergent Literacy Skills to Name Writing, Letter Writing, and Spelling in Preschool Children

    Science.gov (United States)

    Puranik, Cynthia S.; Lonigan, Christopher J.; Kim, Young-Suk

    2011-01-01

    The purpose of this study was to examine which emergent literacy skills contribute to preschool children's emergent writing (name-writing, letter-writing, and spelling) skills. Emergent reading and writing tasks were administered to 296 preschool children aged 4-5 years. Print knowledge and letter-writing skills made positive contributions to name…

  15. 40 CFR 280.115 - Replenishment of guarantees, letters of credit, or surety bonds.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 26 2010-07-01 2010-07-01 false Replenishment of guarantees, letters... Replenishment of guarantees, letters of credit, or surety bonds. (a) If at any time after a standby trust is... were drawn upon, replenishment shall occur by the earliest anniversary date among the mechanisms....

  16. Does Location Uncertainty in Letter Position Coding Emerge Because of Literacy Training?

    Science.gov (United States)

    Perea, Manuel; Jiménez, María; Gomez, Pablo

    2016-01-01

    In the quest to unveil the nature of the orthographic code, a useful strategy is to examine the transposed-letter effect (e.g., JUGDE is more confusable with its base word, JUDGE, than the replacement-letter nonword JUPTE). A leading explanation of this phenomenon, which is in line with models of visual attention, is that there is perceptual…

  17. A Letter from Edmund Husserl to Franz Brentano from 29 XII 1889

    NARCIS (Netherlands)

    Ierna, Carlo

    2015-01-01

    Among the correspondence between Husserl and Brentano kept at the Houghton Library of Harvard University there is a letter from Husserl to Brentano from 29 XII 1889, whose contents were completely unknown until now. The letter is of some significance, both historically as well as systematically for

  18. Letter-Sound Reading: Teaching Preschool Children Print-to-Sound Processing

    Science.gov (United States)

    Wolf, Gail Marie

    2016-01-01

    This intervention study investigated the growth of letter sound reading and growth of consonant-vowel-consonant (CVC) word decoding abilities for a representative sample of 41 US children in preschool settings. Specifically, the study evaluated the effectiveness of a 3-step letter-sound teaching intervention in teaching preschool children to…

  19. 76 FR 68257 - Letters of Interest for Credit Assistance Under the Transportation Infrastructure Finance and...

    Science.gov (United States)

    2011-11-03

    ... Credit Assistance Under the Transportation Infrastructure Finance and Innovation Act (TIFIA) Program... Transportation Infrastructure Finance and Innovation Act of 1998 (TIFIA), authorizing the U.S. Department of... letter and detailed plan of finance). Letters of Interest submitted pursuant to this notice of...

  20. DOCUMENTARY LETTER OF CREDIT IN THE REGULATION OF 600-PARIS PUBLICATION

    Directory of Open Access Journals (Sweden)

    VASILE NEMES

    2011-04-01

    Full Text Available In the year 2007 was adopted the Publication no. 600 of Paris regarding the Rules and the Uniform Practices for documentary letters of credit which replaced the Publication no. 500. Publication no. 600 (UCP 600 is applied to all the irrevocable documentary letters of credit when the parties make express reference to these Rules. The Publication no. 600 includes uniform rules, international practices and standards of irrevocable documentary letters of credit. The new Publication has brought a number of changes on the issues regarding the performance of the letters of credit, both in the relationship with the nonbanking institutions participants and in the relationship between the credit institutions participating in the performance of the letter of credit. This study, without being exhaustive, aims to capture the main aspects of novelty brought by the publication no. 600 and their legal approach to the new perspective of the international trade relations. It has in view, in particular, the irrevocable character of the letter of credit, the elaboration method and procedure of the letter of credit, the participants to the unfolding of the specific relationship of the letter of credit and the main duties of the involved credit institutions.

  1. Letter and Numeral Identification: Their Relationship with Early Literacy and Numeracy Skills

    Science.gov (United States)

    Neumann, Michelle M.; Hood, Michelle; Ford, Ruth M.; Neumann, David L.

    2013-01-01

    The relationship between letter and numeral identification is reviewed to determine whether early identification of these symbols impact upon both literacy and numeracy development. Numerals and letters share similar perceptual properties such as geometric features and arbitrary labels. Through early socio-cultural experiences with surrounding…

  2. I like Cities; Do You like Letters? Introducing Urban Typography in Art Education

    Science.gov (United States)

    Huerta, Ricard

    2010-01-01

    This article proposes a study of the letters and graphics found in the city, while at the same time opening up unusual spaces linked to the cultural arena and visual geographies for the creation of learning spaces in art education, introducing urban typography for training teachers. The letters in urban spaces can help us reinterpret the…

  3. The Rhetoric of Martin Luther King, Jr.: Letter from Birmingham Jail

    Science.gov (United States)

    Mott, Wesley T.

    1975-01-01

    Argues that the success of 'The Letter' can be attributed to the confluence of three distinct rhetorical traits: King's heritage of the highly emotional Negro preaching tradition, his shrewd sense of political timing and polemical skill, and his conscious literary ability, and notes that 'The Letter' is one of the most frequently collected items…

  4. George gives to geology Jane : the name letter effect and incidental similarity cues in fundraising

    NARCIS (Netherlands)

    Bekkers, René H.F.P.

    2010-01-01

    - People tend to like others with attributes similar to their own (the similarity principle) and favor products with names similar to their own (the name letter effect). - In the present field experiment, the name letter effect and similarity principle are tested in a phonaton among alumni of Utrech

  5. The Rhetorical Construction of Time in Martin Luther King, Jr.'s "Letter from Birmingham Jail."

    Science.gov (United States)

    Lee, Ronald E.

    1991-01-01

    Explores the rhetorical use of time in Martin Luther King, Jr.'s "Letter from Birmingham Jail." Offers an explanation of the ideological heritage that temporarily unifies the discourse. Describes the letter's recent, historical, and spiritual time frames, accounts for the ideological purpose each serves, and explains on what ground they…

  6. 31 CFR 535.576 - Payment of non-dollar letters of credit to Iran.

    Science.gov (United States)

    2010-07-01

    ... credit to Iran. 535.576 Section 535.576 Money and Finance: Treasury Regulations Relating to Money and... letters of credit to Iran. Notwithstanding the prohibitions of §§ 535.201 and 535.206(a)(4), payment of existing non-dollar letters of credit in favor of Iranian entities or any person in Iran by any...

  7. The temporal dynamics of implicit processing of non-letter, letter, and word-forms in the human visual cortex.

    Science.gov (United States)

    Appelbaum, Lawrence G; Liotti, Mario; Perez, Ricardo; Fox, Sarabeth P; Woldorff, Marty G

    2009-01-01

    The decoding of visually presented line segments into letters, and letters into words, is critical to fluent reading abilities. Here we investigate the temporal dynamics of visual orthographic processes, focusing specifically on right hemisphere contributions and interactions between the hemispheres involved in the implicit processing of visually presented words, consonants, false fonts, and symbolic strings. High-density EEG was recorded while participants detected infrequent, simple, perceptual targets (dot strings) embedded amongst a of character strings. Beginning at 130 ms, orthographic and non-orthographic stimuli were distinguished by a sequence of ERP effects over occipital recording sites. These early latency occipital effects were dominated by enhanced right-sided negative-polarity activation for non-orthographic stimuli that peaked at around 180 ms. This right-sided effect was followed by bilateral positive occipital activity for false-fonts, but not symbol strings. Moreover the size of components of this later positive occipital wave was inversely correlated with the right-sided ROcc180 wave, suggesting that subjects who had larger early right-sided activation for non-orthographic stimuli had less need for more extended bilateral (e.g., interhemispheric) processing of those stimuli shortly later. Additional early (130-150 ms) negative-polarity activity over left occipital cortex and longer-latency centrally distributed responses (>300 ms) were present, likely reflecting implicit activation of the previously reported 'visual-word-form' area and N400-related responses, respectively. Collectively, these results provide a close look at some relatively unexplored portions of the temporal flow of information processing in the brain related to the implicit processing of potentially linguistic information and provide valuable information about the interactions between hemispheres supporting visual orthographic processing.

  8. From graphemes to abstract letter shapes: levels of representation in written spelling.

    Science.gov (United States)

    Rapp, B; Caramazza, A

    1997-08-01

    The letter substitution errors of 2 dysgraphic subjects who, despite relatively intact oral spelling, made well-formed letter substitution errors in written spelling, were studied. Many of these errors bear a general physical similarity to the intended target. Analyses revealed that this similarity apparently was based on the features of the component strokes of letters rather than on visuospatial characteristics. A comparison of these subjects' letter substitution errors with those of 2 other individuals with brain damage, whose damage was at a different level of processing, revealed that the latter subjects' errors are not explicable in terms of stroke-feature similarity. Strong support was found for the computation of multiple representational types in the course of written spelling. This system includes a relatively abstract, effector-independent representational level that specifies the features of the component strokes of letters.

  9. A New Demonstration of the Illusory Letters Phenomenon: Graphemic Restoration in Arabic Word Perception.

    Science.gov (United States)

    Jordan, Timothy R; Sheen, Mercedes; AlJassmi, Maryam A; Paterson, Kevin B

    2015-02-01

    The illusory letters phenomenon (ILP) is a unique demonstration that words can be perceived as complete even when letters are physically absent. However, the ILP has only ever been reported for a Latinate language (English), and it is unknown whether the illusion occurs for alphabetic languages with fundamentally different visual properties. Here we report a demonstration of the ILP for Arabic in which stimuli containing only the exterior letters of three-letter Arabic words and a nonsense pattern in the interior position were presented to fluent Arabic readers. Despite being incomplete, participants perceived these stimuli as complete Arabic words with all letters visible in their appropriate positions, and were unable to distinguish between illusory and normal displays. This finding provides an important extension of the original ILP and suggests that alphabetic languages may be widely susceptible to the phenomenon and reading generally may occur as a process augmented by illusory percepts.

  10. Visual and Artistic Functions of Letters in Khaghani’s Poetry

    Directory of Open Access Journals (Sweden)

    Mohsen Zolfaghari

    2013-11-01

    Full Text Available Abstract The intensity of emotion and fluctuation of meaning in the poet's mind causes him to go beyond the ordinary language and convey intellectual and emotional meanings through metaphors, similes and linguistic preparations. He has sharp eyes and a sensitive spirit and creative temperament and attempts strengthening his own literary language and creating personal style by inventing novel images, showing the creativity and imagination and entering in various arenas of imagination. This point more than anything else could be done by presenting images and new figures. Perhaps in the sixth century, and especially in Azerbaijani school, more than other periods, poets have been looking for creating innovative style in eloquence. Their major attempts were mainly in imaging, a wide field that they have competed. It is obvious that in this illustration the alphabet letters would be very helpful. Khaghani's Divan of poetry, as one of the greatest poets of this school, is the perfect poetical book of paintings in which meaning has been hidden under a delicate pattern and new different scientific, cultural and religious images. Letters are a broad range of elements that put a new field in front of the poet and he is aware of the potential features of the letters, new images, and artistic creativity techniques as well. This paper shows descriptive - analytical study of various aspects of Khaghani’s poetry and frequency of letters in the alphabet letters, alphabetic-based authenticity of images, different similarity reasons, semantic and literal multi-relevance of letters in the context of poetry, producing figures of speech based on letters, sensational relationship exists between images and letters which have been shown in his poetry. Letter have a double and even multiple application in Khaghani's poetic works (divan and moreover the construction of words and conveying meaning which is the real and common usage, they were used as artistic instruments

  11. Masked form priming is moderated by the size of the letter-order-free orthographic neighbourhood.

    Science.gov (United States)

    Burt, Jennifer S; Duncum, Sophie

    2016-03-16

    University students made lexical decisions to targets preceded by masked primes. In Experiment 1, transposed-letter primes were used also in the sandwich priming paradigm, in which the target is briefly pre-presented prior to the prime. The priming effects in the masked paradigm, but not in the sandwich paradigm, were moderated by the density of the letter-order-free neighbourhood of the target. In Experiment 2, letter-order-free neighbour prime words produced a priming cost in masked priming. These results are consistent with the idea that sandwich priming attenuates letter-order-free neighbour competition in target identification. Unexpectedly, no priming cost was produced by conventional (letter-position-preserving) word neighbour primes. Order-free neighbours may produce facilitation of target processing less, and more variably, than conventional neighbours.

  12. Hunan Rare Earth Group Approved

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>Following Guangdong,Guangxi,Fujian and Jiangxi,Hunan announced that it would consolidate its rare earth resources-the consolidation plan of Hunan Rare Earth Group has been approved. Consolidation of the rare earth industry of south China is in full swing.According to "Several Opinions of the State Council on Promoting the Sustainable and Healthy Development of Rare Earth Industry"(hereinafter referred to as "Several Opinions")released in 2011,

  13. Nelfinavir: fourth protease inhibitor approved.

    Science.gov (United States)

    1997-01-01

    The Food and Drug Administration (FDA) has granted accelerated approval to nelfinavir in both adult and pediatric formulations. Agouron, the manufacturer, used innovative computerized drug design techniques to discover, design, and refine the nelfinavir molecule. Nelfinavir is marketed under the trade name Viracept, and costs $5,000 per year. Early clinical trials find it to be as powerful as the other protease inhibitors, but with a different resistance profile. The drug has relatively few drug indications; however, several compounds have been contraindicated.

  14. Sin and Guilt of Hester in The Scarlet Letter

    Institute of Scientific and Technical Information of China (English)

    张伶俐

    2010-01-01

    身为加尔文教派一员的霍桑深受基督教原罪思想的影响,并以祖先们对贵格会教徒的迫害为耻,这些经历通常使霍桑的作品中带有罪恶感的基调.作为霍桑的代表作就清晰的反映了他的这一思想.作者虽然认为人生而有罪,但并不相信罪恶的不可饶恕性.他鼓励人们通过善行来解除自己的罪恶.霍桑深信善举不仅能弥补罪恶,更能净化心灵,甚至可以是堕落的罪者转变为令人敬仰的凡间天使.女主人公海斯特正是这样形象的一个很好例证.霍桑通过对中主人公心理矛盾产生及化解的刻画和他们形象转变的描述,成功的完成了小说主题的深化和升华.%Nathaniel Hawthorne,a leading American writer and a Calvinist,was shameful for his ancestors'misdeeds and influenced greatly by the Christian view of"original sin".He believes that humankind was bom sinful.This kind of his thought can be reflected clearly in his masterpiece The Scarlet Letter.He keeps a criticize eye on the adultery sin Hester Prynne and Arthur Dimmesdale committed,blames the cold revenge of Roger Chillingworth.But he does not consider that sin is not unforgivable.People can remedy their sin by goodness.God will also send angel to help people realize their sin and stops them from further sin,eg.Pearl.Hester were forgiven by God at the end of the novel.Hester even becomes a kind of compassionate maternal figure through her persisted helping to the poor and the needy.Thus,Hawthorne successfully portrays the heroine,with the theme of"original sin"of The Scarlet Letter.

  15. The Physicist and Astronomer Christoper Scheiner - Biography Letters, Works

    Science.gov (United States)

    Daxecker, Franz

    The Jesuit priest Christopher Scheiner was one of the most influential astronomers of the first half of the 17th century. He was a creative and down-to-earth natural scientist who worked in the fields of astronomy, physics, optics and ophthalmology, while following his vocations as university lecturer, church builder and pastor. In scientific matters he was Galilei's opponent. Their dispute centred on the priority of discovery in regard to the sunspots. Scheiner was not the first to discover the sunspots, but he gave the most detailed account thereofin his main work "Rosa Ursina sive Sol". He was, however, ceaseless in his defense of the geocentric system. In 1891, Anton v.Braunmühl published a biography of Father Scheiner. Ever since then, new documents have come to light, justifying the publication of a new biography. Among the documents now available is Scheiner's hitherto unknown dissertation. Notes taken during his lectures in Ingolstadt provide valuable information on astronomy using the telescope, an invention of his lifetime. His exchange of letters with personalities like Archduke Leopold V of Austria-Tyrol, with scientists like Magini, Galilei, Gassendi, Kepler and confriars Rader, Guldin, Alber, Minutuli, Cysat und Kircher is a source of precious insights. Letters to Scheiner from the Father Generals of his order display evidence of his superiors' zero tolerance for the helincentric system. They also disclose Scheiner's wish to become a missionary in China, the financial difficulties he faced while trying to find a publisher for his "Rosa Ursina sive Sol" and his personal shortcomings. A Scheiner obituary from 1650 was found in Cracow in 2001. It contains information on the troublesome last years of his life and has finally allowed us to determine the year of his birth. Scheiner's personality has been praised as well as criticized by many authors - sometimes depending on their ideological backgrounds. This holds true especially regarding the argument

  16. Nursing empire: travel letters from Africa and the Caribbean.

    Science.gov (United States)

    Howell, Jessica

    2013-02-01

    This essay analyses colonial nurses' travel letters, written from West Africa and the Caribbean between the turn of the century and 1920, in order to better understand the role of nurses in forming satellite versions of home. Though their primary function was to 'nurse empire' by helping to repair and maintain the bodies needed for imperial labour, nurses also contributed to written discourses supporting Britain's economic interests and political goals. Through careful consideration of primary archival material, this essay analyses the rhetorical modes that may have helped nurses gain professional and personal authority abroad. It considers nurses as moving within several kinds of imperial networks - geographical, institutional and discursive - and traces the shifts in their written self-representation according to these different contexts. In order to reform nursing, in the mid-nineteenth century Florence Nightingale defined the 'New Nurse's' ideal personality as well as her duties. Ever since, the nurse's 'character' has often been essentialised in literature and culture. As Julia Hallam observes in Nursing the Image (2000), the nurse is commonly portrayed as ministering angel, potential seductress, battleaxe or doctor's helpmate. The goal of this essay is to resist simplifying nurses' cultural significance, motivations or experiences by studying the multiple influences to which colonial nurses were subject and the shifting registers in their writing.

  17. Desejo de encadear letras A desire to enchain letters

    Directory of Open Access Journals (Sweden)

    Cristóvão Giovani Burgarelli

    2009-04-01

    Full Text Available Este texto se propõe pensar algumas questões sobre a entrada da criança em processo de alfabetização na leitura e na produção textual. Partindo da discussão sobre a relação entre a criança, o professor e o texto, busca-se uma articulação entre essas três instâncias e o conceito de inconsciente, cuja estrutura é a da linguagem. Situando-se, por fim, que se trata da constituição de um sujeito desejante, serão privilegiados os conceitos psicanalíticos de pulsão, escrita e letra.This text proposes to think through some issues round the introduction to reading and writing of the child who is being made literate. Starting out from a discussion of the relationship between child, teacher and text, it will seek to articulate these three instances and the concept of the unconscious, whose structure is that of language. Finally, situating itself where the building of a desiring subject occurs, it will prioritize the psychoanalytical concepts of pulsation, writing and letter.

  18. THE INTERLOCUTOR IN THE PRODUCTION OF PERSONAL LETTERS IN CLASSROOM

    Directory of Open Access Journals (Sweden)

    Ednéia Aparecida Bernardineli BERNINI

    2013-12-01

    Full Text Available Considering a teaching-learning conception based on the discourse as a social practice, experiences in reading and writing in classroom become more meaningful, because resources that allow the student to assume a dialogic attitude are valued. In this perspective, this paper aims to analyze the presence of the interlocutor/other in personal letters of students from the eighth grade / elementary school of a private school of the municipality of Marialva – Paraná. The presence of traces of a real interlocutor and an external real interlocutor will be analyzed, since the proposal requested a receiver. Even so, a virtual and an internal interlocutor are observed. To support this analysis, readings and concepts developed by the Circle of Bakhtin and by Brazilian researches that approach this theory were used. What is evident was the constant traces of a real external interlocutor, but, also, some writing evidences for a real interlocutor, in addition to the insignificant traces of a virtual interlocutor and no trace of an internal interlocutor. The results of the analysis show that the students do not show maturity in the use of the elements of a text, including, the interlocutor.

  19. THE INTERLOCUTOR IN THE PRODUCTION OF PERSONAL LETTERS IN CLASSROOM

    Directory of Open Access Journals (Sweden)

    Ednéia Aparecida Bernardineli Bernini

    2014-05-01

    Full Text Available : Considering a teaching-learning conception based on the discourse as a social practice, experiences in reading and writing in classroom become more meaningful, because resources that allow the student to assume a dialogic attitude are valued. In this perspective, this paper aims to analyze the presence of the interlocutor/other in personal letters of students from the eighth grade / elementary school of a private school of the municipality of Marialva – Paraná. The presence of traces of a real interlocutor and an external real interlocutor will be analyzed, since the proposal requested a receiver. Even so, a virtual and an internal interlocutor are observed. To support this analysis, readings and concepts developed by the Circle of Bakhtin and by Brazilian researches that approach this theory were used. What is evident was the constant traces of a real external interlocutor, but, also, some writing evidences for a real interlocutor, in addition to the insignificant traces of a virtual interlocutor and no trace of an internal interlocutor. The results of the analysis show that the students do not show maturity in the use of the elements of a text, including, the interlocutor.

  20. BUDGET IN DANGER : OUR LETTER TO THE MINISTERS

    CERN Multimedia

    STAFF ASSOCIATION

    2010-01-01

    In edition no. 104 of Echo we told you about the Finance Committee meeting which took place on Wednesday 16 June and the tense atmosphere that reigned during this meeting. Echoing the alarming news from most of our countries (budget cuts, restrictions, reforms), CERN’s global budget is indeed under pressure. This is extremely serious. How can we carry out our mission if our Member States do not give us the means? Basic research cannot progress with budget cuts. The Management tried to make this understood at the meeting, however, most delegations could not or would not see reason. Refusing to sit idly by, the Staff Association decided to act immediately. It sent a letter to all ministers in the twenty Member States concerned by CERN and its financing. A copy was also sent to all Finance Committee and Council delegates. We thus hope to help convince all our Member States that it is essential that they continue to invest in basic research, a breeding ground for new ideas and at the roo...