WorldWideScience

Sample records for application reference efsa-gmo-uk-2005-21

  1. 43 CFR 3.8 - Applications referred for recommendation.

    Science.gov (United States)

    2010-10-01

    ... 43 Public Lands: Interior 1 2010-10-01 2010-10-01 false Applications referred for recommendation... AMERICAN ANTIQUITIES § 3.8 Applications referred for recommendation. Applications for permits shall be referred to the Smithsonian Institution for recommendation....

  2. Generating application ontologies from reference ontologies.

    Science.gov (United States)

    Shaw, Marianne; Detwiler, Landon T; Brinkley, James F; Suciu, Dan

    2008-11-06

    The semantic web provides the possiblity of linking together large numbers of biomedical ontologies. Unfortunately, many of the biomedical ontologies that have been developed are domain-specific and do not share a common structure that will allow them to be easily combined. Reference ontologies provide the necessary ontological framework for linking together these smaller, specialized ontologies. We present extensions to the semantic web query language SparQL that will allow researchers to develop application ontologies that are derived from reference ontologies. We have modified the ARQ query processor to support subqueries, recursive subqueries, and Skolem functions for node creation. We demonstrate the utility of these extensions by deriving an application ontology from the Foundational Model of Anatomy.

  3. Generating Application Ontologies from Reference Ontologies

    OpenAIRE

    Shaw, Marianne; Detwiler, Landon T.; Brinkley, James F.; Suciu, Dan

    2008-01-01

    The semantic web provides the possiblity of linking together large numbers of biomedical ontologies. Unfortunately, many of the biomedical ontologies that have been developed are domain-specific and do not share a common structure that will allow them to be easily combined. Reference ontologies provide the necessary ontological framework for linking together these smaller, specialized ontologies.

  4. Microfabricated Reference Electrodes and their Biosensing Applications

    Directory of Open Access Journals (Sweden)

    M. Jamal Deen

    2010-03-01

    Full Text Available Over the past two decades, there has been an increasing trend towards miniaturization of both biological and chemical sensors and their integration with miniaturized sample pre-processing and analysis systems. These miniaturized lab-on-chip devices have several functional advantages including low cost, their ability to analyze smaller samples, faster analysis time, suitability for automation, and increased reliability and repeatability. Electrical based sensing methods that transduce biological or chemical signals into the electrical domain are a dominant part of the lab-on-chip devices. A vital part of any electrochemical sensing system is the reference electrode, which is a probe that is capable of measuring the potential on the solution side of an electrochemical interface. Research on miniaturization of this crucial component and analysis of the parameters that affect its performance, stability and lifetime, is sparse. In this paper, we present the basic electrochemistry and thermodynamics of these reference electrodes and illustrate the uses of reference electrodes in electrochemical and biological measurements. Different electrochemical systems that are used as reference electrodes will be presented, and an overview of some contemporary advances in electrode miniaturization and their performance will be provided.

  5. A reference accelerator scheme for ADS applications

    Energy Technology Data Exchange (ETDEWEB)

    Biarrotte, Jean-Luc [CNRS/IN2P3, Institut de Physique Nucleaire, 91406 Orsay (France)]. E-mail: biarrott@ipno.in2p3.fr; Bousson, Sebastien [CNRS/IN2P3, Institut de Physique Nucleaire, 91406 Orsay (France); Junquera, Tomas [CNRS/IN2P3, Institut de Physique Nucleaire, 91406 Orsay (France); Mueller, Alex C. [CNRS/IN2P3, Institut de Physique Nucleaire, 91406 Orsay (France); Olivier, Aurelia [CNRS/IN2P3, Institut de Physique Nucleaire, 91406 Orsay (France)

    2006-06-23

    Accelerator Driven Systems (ADS) for transmutation of nuclear waste typically require 350MeV-1GeV accelerators delivering proton fluxes of 5-10mA for demonstrators, and 20-50mA for large industrial systems. Thus, such machines belong to the category of the so-called HPPA (High-Power Proton Accelerators), with multi-megawatt beam power. HPPA are presently developed and constructed at great pace for their broad utility in fundamental or applied science. Compared to other HPPA, many features and requirements are similar for the ADS driver. However, there is a need for exceptional reliability: because of the induced thermal stress to the sub-critical core, the number of unwanted 'beam-trips' should not exceed a few per year, a requirement that is several orders of magnitude above usual performance. Consecutive to the work of the European Technical Working Group (ETWG) on ADS, the Preliminary Design Study of an Experimental ADS (PDS-XADS) was launched in 2001 as a 5th Framework Program EC project. A special Working Package (WP3) was dedicated to the accelerator design, taking especially into account that the issue of 'beam-trips' could be a potential 'show-stopper' for ADS technology in general. A reference solution, based on a linear superconducting accelerator with its associated doubly achromatic beam line, has been worked out to some detail. For high reliability, the proposed design is intrinsically fault tolerant, relying on highly modular 'de-rated' components associated to a fast digital feedback system. The proposed solution also appears to be robust concerning operational aspects like maintenance and radioprotection. A roadmap for construction as well as the required consolidated budget was elaborated. A program for the remaining R and D, focused on experimental reliability demonstration of prototypical components has been elaborated. This R and D will be performed in the 6th Framework Program EC project EUROTRANS, which

  6. Applicability of Virtual Reference Stations for Static and Kinematic Positioning

    Science.gov (United States)

    Kalita, Jakub; Rzepecka, Zofia

    2013-04-01

    There is a possibility to generate artificial observations for a particular position by using a known Virtual Reference Station technique. It is done by transferring the observations from a physical reference station and interpolating the biases, usually using a network of reference stations. Theoretically, the measurements can replace the physical reference receiver and both, simplify and improve the processing of static and kinematic measurements. Here, the VRS is used as a control station for static and kinematic post-processing taking advantage of the network of reference stations by interpolating ionospheric and tropospheric biases to location of measurement. However previous computational experiments showed that the generated virtual observations are strongly correlated with the observations gathered at the nearest physical reference station. The previous studies were performed at close vicinity of the physical reference station. For further investigations of these correlations, and the issue of how do they influence processing results, a field experiment was designed and performed, in which the real measurements were taken at various distances from the physical reference station. Basing on these measurements, the correlations between the reference station and VRS stations were studied. The unknown physical stations were determined and used as a comparison for VRS measurements. Also, the applicability of VRS observations for static and kinematic processing was validated. To assure independence of calculations and results, besides commercial software (GNSS Solutions and LGO) chosen Precise Point Positioning services were used. The VRS data were obtained from the POZGEO-D service of the ASG-EUPOS network.

  7. LCCP Desktop Application v1.0 Engineering Reference

    Energy Technology Data Exchange (ETDEWEB)

    Beshr, Mohamed [University of Maryland, College Park; Aute, Vikrant [University of Maryland, College Park

    2014-04-01

    This Life Cycle Climate Performance (LCCP) Desktop Application Engineering Reference is divided into three parts. The first part of the guide, consisting of the LCCP objective, literature review, and mathematical background, is presented in Sections 2-4. The second part of the guide (given in Sections 5-10) provides a description of the input data required by the LCCP desktop application, including each of the input pages (Application Information, Load Information, and Simulation Information) and details for interfacing the LCCP Desktop Application with the VapCyc and EnergyPlus simulation programs. The third part of the guide (given in Section 11) describes the various interfaces of the LCCP code.

  8. Practical considerations in the development and application of reference levels

    Energy Technology Data Exchange (ETDEWEB)

    Selby, J. M.; Kennedy, W. E. Jr.; Swinth, K. L.; Gilbert, R. O.; Soldat, J. K.

    1988-05-01

    Radiological exposures to the public during an accident that releases radioactive materials to the environment occur initially through the air pathway, secondly through a water pathway, and finally, through the food chain. From these exposure pathways, reference levels of radionuclides must be applied to limit public radiation doses. Such reference levels are difficult to develop and apply, particularly if the contaminants are transuranic elements such as plutonium. The reference level must be related to a resultant theoretical dose to the public through generic calculations. However, to permit rapid decisions after an accident, the reference levels need to be related to conditions or media in the environment that can be directly measured. They must also be tied to specific countermeasures such as sheltering, evacuation, or interdiction of drinking water or food supplies. This paper discusses the practical considerations in the development and application of reference levels for transuranic in the environment and the present capability to rapidly detect and quantify their concentrations following accidental contamination events. 16 refs., 3 tabs.

  9. Opportunities for ISRU Applications in the Mars Reference Mission

    Science.gov (United States)

    Duke, Michael B.

    1998-01-01

    The NASA Mars Exploration Reference Mission envisions sending three crews of six astronauts to Mars, each for 500-day stays on the surface. In situ Resourse Unitlization (ISRU) has been baselined for the production of propellant for crews leaving the surface, as well as to create reservoirs of water and life-support consumables These applications improve performance (by reducing the mass of hardware and supplies that must be brought to Mars for the propulsion system) and reduce risk (by creating consumables as backups to stores brought from Earth). Similar applications of other types of ISRU-derived materials should be sought and selected if they similarly improve performance or reduce risk. Some possible concepts for consideration, based on a review of the components included in the Reference Mission, include (1) emplacement of a hardened landing pad; (2) construction of a roadway for transporting the nuclear power system to a safe distance from the habitat; (3) radiation shielding for inflatable structures; (4) tanks and plumbing for bioregenerative life-support system; (5) drilling rig; (6) additional access structures for equipment and personnel and unpressurized structures for vehicle storage; (7) utilitarian manufactured products (e.g., stools and benches) for habitat and laboratory; (8) thermal radiators; (9) photovoltaic devices and support structures; and ( 10) external structures for storage and preservation of Mars samples. These may be viewed principally as mission- enhancing concepts for the Reference Mission. Selection would require a clear rationale for performance improvement or risk reduction and a demonstration that the cost of developing and transporting the needed equipment would be recovered within the budget for the program. Additional work is also necessary to ascertain whether early applications of ISRU for these types of purposes could lead to the modification of later missions, allowing the replacement of infrastructure payloads currently

  10. An iodine-based frequency reference for space applications

    Science.gov (United States)

    Schuldt, Thilo; Johann, Ulrich; Doeringshoff, Klaus; Kovalchuk, Evgeny; Peters, Achim; Braxmaier, Claus; Pahl, Julia; Stuehler, Johannes; Franz, Matthias

    We present the development of an iodine-based frequency reference for future potential applications in space, including the gravitational wave detector LISA/eLISA (Laser Interferometer Space Antenna), the mini SpaceTime Asymmetry Research (mSTAR) program, the aperture-synthesis telescope Darwin and the GRACE (Gravity Recovery and Climate Experiment) follow on mission/NGGM (Next Generation Gravity Mission) exploring Earth's gravity. Based on a state-of-the-art laboratory iodine frequency reference, setups on elegant breadboard (EBB) and engineering model (EM) level were realized, taking into account specific design criteria for space compatibility such as compactness and robustness. Both setups employ modulation transfer spectroscopy (MTS) in combination with balanced detection. They use a baseplate made of glass material in combination with a dedicated easy-to-handle assembly-integration technology (adhesive bonding) ensuring high pointing stability of the two counter-propagating laser beams in the iodine cell and therefore high long-term stability. The EBB setup utilizes a commercial off-the-shelf 30 cm long iodine cell in triple-pass configuration, the EM setup a specifically designed and manufactured compact iodine cell made of fused silica in a nine-pass configuration with a specific robust cold finger design. Both setups were characterized in beat measurements with a ULE cavity setup. Similar frequency stabilities of about 1*10 (-14) at an integration time of 1 s and below 5*10 (-15) at integration times between 10 s and 100 s were demonstrated. These values are comparable to the currently best laboratory setups. The EM setup was further subjected to environmental testing including thermal cycling and vibrational testing. Financial support by the German Space Agency DLR with funds provided by the Federal Ministry of Economics and Technology (BMWi) under grant numbers 50 QT 1102 and 50 QT 1201 is highly appreciated. The authors thank Jan Hrabina and Josef Lazar

  11. A Reliable Reference Electrode in Molten Carbonate and Its Applications

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    A Ag|AgCl reference electrode which can be used in molten carbonate media has been described in this paper.It consists of a silver wire immersed in a solution of AgCl(1mol%) in (Li0.62,K0.38)2CO3,with a zirconia junction.The main properties of reference electrode,such as reproducibility ,stability and reversibility, were checked.The results have demonstrated that the reference electrode is reliable.With such reference electrode catalysis of various electrode materials to oxygen reduction in molten alkali carbonate media was investigated.It is found that as catalysts for oxygen reduction oxidized nickel-niobium alloy is superior to nickel oxide.

  12. Reference clock parameters for digital communications systems applications

    Science.gov (United States)

    Kartaschoff, P.

    1981-01-01

    The basic parameters relevant to the design of network timing systems describe the random and systematic time departures of the system elements, i.e., master (or reference) clocks, transmission links, and other clocks controlled over the links. The quantitative relations between these parameters were established and illustrated by means of numerical examples based on available measured data. The examples were limited to a simple PLL control system but the analysis can eventually be applied to more sophisticated systems at the cost of increased computational effort.

  13. Neutron imaging and applications a reference for the imaging community

    CERN Document Server

    McGreevy, Robert L; Bilheux, Hassina Z

    2009-01-01

    Offers an introduction to the basics of neutron beam production in addition to the wide scope of techniques that enhance imaging application capabilities. This title features a section that describes imaging single grains in polycrystalline materials, neutron imaging of geological materials and other materials science and engineering areas.

  14. Comprehensive NASA Cis-Lunar Earth Moon Libration Orbit Reference and Web Application Project

    Data.gov (United States)

    National Aeronautics and Space Administration — To finalize a comprehensive NASA Cis-Lunar / Earth-Moon Libration Orbit Reference and Web Application begun using FY13 IRAD funding approved in May 2013. This GSFC...

  15. Dietary reference intakes: aplicabilidade das tabelas em estudos nutricionais Dietary reference intakes: application of tables in nutritional studies

    Directory of Open Access Journals (Sweden)

    Renata Maria Padovani

    2006-12-01

    1997 and known as Dietary Reference Intakes, offer a new model by establishing indices of nutrient intake and refining the concept of risk associated with diet evaluation. Errors of both intra and interindividual nature, due to the variability of an individual's feeding pattern, the uneven distribution of requirements within a population, respectively, and the small number of days of observation, are factors that together can have a large impact on the confidence of the analysis. For these reasons, only the judicious selection of the reference values, published in the form of tables from 1997 through 2005, should enable the user to reach the proper assessment. This paper had the objective of highlighting various critical characteristics of application and compiling the values in order to facilitate their use by both professionals and students of the area.

  16. 18 CFR 1300.101 - Cross references to employee ethical conduct standards and other applicable regulations.

    Science.gov (United States)

    2010-04-01

    ... employee ethical conduct standards and other applicable regulations. 1300.101 Section 1300.101 Conservation of Power and Water Resources TENNESSEE VALLEY AUTHORITY STANDARDS OF CONDUCT FOR EMPLOYEES OF TENNESSEE VALLEY AUTHORITY § 1300.101 Cross references to employee ethical conduct standards and...

  17. Evaluation and applicability of transfinite element formulations with particular reference to radiation

    Science.gov (United States)

    Tamma, Kumar K.; Railkar, Sudhir B.

    1988-01-01

    The evaluation and applicability of hybrid transfinite element formulations are described for transient nonlinear thermal models with particular reference to account for radiation effects. The formulations are developed from basic concepts and evaluated for both one- and two-dimensional thermal models. The methodology presented is a hybrid approach as it combines finite elements, classical Galerkin schemes, and transform methods. Basic features of the hybrid formulations and the associated solution scheme used are first described. Therein, numerical test models are presented to evaluate the applicability for predicting the nonlinear transient response in one- and two-dimensional thermal models influenced due to radiation effects.

  18. 41 CFR 102-118.185 - When buying freight transportation, must my agency reference the applicable contract or tender on...

    Science.gov (United States)

    2010-07-01

    ... transportation, must my agency reference the applicable contract or tender on the bill of lading (including a GBL... Government Bill of Lading (gbl) Or Government Transportation Request (gtr) (until Form Retirement) § 102-118... the bill of lading (including a GBL)? Yes, your agency must reference the applicable contract...

  19. Reference tissue modeling with parameter coupling: application to a study of SERT binding in HIV

    Science.gov (United States)

    Endres, Christopher J.; Hammoud, Dima A.; Pomper, Martin G.

    2011-04-01

    When applicable, it is generally preferred to evaluate positron emission tomography (PET) studies using a reference tissue-based approach as that avoids the need for invasive arterial blood sampling. However, most reference tissue methods have been shown to have a bias that is dependent on the level of tracer binding, and the variability of parameter estimates may be substantially affected by noise level. In a study of serotonin transporter (SERT) binding in HIV dementia, it was determined that applying parameter coupling to the simplified reference tissue model (SRTM) reduced the variability of parameter estimates and yielded the strongest between-group significant differences in SERT binding. The use of parameter coupling makes the application of SRTM more consistent with conventional blood input models and reduces the total number of fitted parameters, thus should yield more robust parameter estimates. Here, we provide a detailed evaluation of the application of parameter constraint and parameter coupling to [11C]DASB PET studies. Five quantitative methods, including three methods that constrain the reference tissue clearance (kr2) to a common value across regions were applied to the clinical and simulated data to compare measurement of the tracer binding potential (BPND). Compared with standard SRTM, either coupling of kr2 across regions or constraining kr2 to a first-pass estimate improved the sensitivity of SRTM to measuring a significant difference in BPND between patients and controls. Parameter coupling was particularly effective in reducing the variance of parameter estimates, which was less than 50% of the variance obtained with standard SRTM. A linear approach was also improved when constraining kr2 to a first-pass estimate, although the SRTM-based methods yielded stronger significant differences when applied to the clinical study. This work shows that parameter coupling reduces the variance of parameter estimates and may better discriminate between

  20. Normalization references for Europe and North America for application with USEtox™ characterization factors

    DEFF Research Database (Denmark)

    Laurent, Alexis; Lautier, Anne; Rosenbaum, Ralph K.;

    2011-01-01

    Purpose: In life cycle impact assessment, normalization can be a very effective tool for the life cycle assessment practitioner to interpret results and put them into perspective. The paper presents normalization references for the recently developed USEtox™ model, which aims at calculating...... globally applicable characterization factors. Normalization references for Europe and North America are determined, and guidance for expansions to other geographical regions is provided. Materials and methods The base years of the European and North American inventories are 2004 and 2002/2008, respectively......, a similar coverage of substances was obtained for both regions with relatively high representation of metals and a number of organic compounds, mainly consisting of non-methane volatile organic compounds and pesticides. The two inventory sets were eventually characterized with the characterization factors...

  1. Application of Model Reference Adaptive Control System to Instrument Pointing System /IPS/

    Science.gov (United States)

    Waites, H. B.

    1979-01-01

    A Model Reference Adaptive Controller (MRAC) is derived for a Shuttle payload called the Instrument Pointing System (IPS). The unique features of this MRAC design are that total state feedback is not required, that the internal structure of the model is independent of the internal structure of the IPS, and that the model input is of bounded variation and not required a priori. An application of Liapunov's stability theorems is used to synthesize a control signal which assures MRAC asymptotic stability. Exponential observers are used to obtain the necessary state information to implement the control synthesis. Results are presented which show how effectively the MRAC can maneuver the IPS.

  2. A Ka-band Celestial Reference Frame with Applications to Deep Space Navigation

    Science.gov (United States)

    Jacobs, Christopher S.; Clark, J. E.; García-Miró, C.; Horiuchi, S.; Sotuela, I.

    2011-10-01

    The Ka-band radio spectrum is now being used for a wide variety of applications. This paper highlights the use of Ka-band as a frequency for precise deep space navigation based on a set of reference beacons provided by extragalactic quasars which emit broadband noise at Ka-band. This quasar-based celestial reference frame is constructed using X/Ka-band (8.4/32 GHz) from fifty-five 24-hour sessions with the Deep Space Network antennas in California, Australia, and Spain. We report on observations which have detected 464 sources covering the full 24 hours of Right Ascension and declinations down to -45 deg. Comparison of this X/Ka-band frame to the international standard S/X-band (2.3/8.4 GHz) ICRF2 shows wRMS agreement of ~200 micro-arcsec (μas) in α cos δ and ~300 μas in δ. There is evidence for systematic errors at the 100 μas level. Known errors include limited SNR, lack of instrumental phase calibration, tropospheric refraction mis-modeling, and limited southern geometry. The motivation for extending the celestial reference frame to frequencies above 8 GHz is to access more compact source morphology for improved frame stability and to support spacecraft navigation for Ka-band based NASA missions.

  3. A Ka-Band Celestial Reference Frame with Applications to Deep Space Navigation

    Science.gov (United States)

    Jacobs, Christopher S.; Clark, J. Eric; Garcia-Miro, Cristina; Horiuchi, Shinji; Sotuela, Ioana

    2011-01-01

    The Ka-band radio spectrum is now being used for a wide variety of applications. This paper highlights the use of Ka-band as a frequency for precise deep space navigation based on a set of reference beacons provided by extragalactic quasars which emit broadband noise at Ka-band. This quasar-based celestial reference frame is constructed using X/Ka-band (8.4/32 GHz) from fifty-five 24-hour sessions with the Deep Space Network antennas in California, Australia, and Spain. We report on observations which have detected 464 sources covering the full 24 hours of Right Ascension and declinations down to -45 deg. Comparison of this X/Ka-band frame to the international standard S/X-band (2.3/8.4 GHz) ICRF2 shows wRMS agreement of approximately 200 micro-arcsec in alpha cos(delta) and approximately 300 micro-arcsec in delta. There is evidence for systematic errors at the 100 micro-arcsec level. Known errors include limited SNR, lack of instrumental phase calibration, tropospheric refraction mis-modeling, and limited southern geometry. The motivation for extending the celestial reference frame to frequencies above 8 GHz is to access more compact source morphology for improved frame stability and to support spacecraft navigation for Ka-band based NASA missions.

  4. Design and Development of Hybrid Multilevel Inverter employing Dual Reference Modulation Technique for Fuel Cell Applications

    Directory of Open Access Journals (Sweden)

    R. Seyezhai

    2011-10-01

    Full Text Available MultiLevel Inverter (MLI has been recognized as an attractive topology for high voltage DC-AC conversion. This paper focuses on a new dual reference modulation technique for a hybrid multilevel inverter employing Silicon carbide (SiC switches for fuel cell applications. The proposed modulation technique employs two reference waveforms and a single inverted sine wave as the carrier waveform. This technique is compared with the conventional dual carrier waveform in terms of output voltage spectral quality and switching losses. An experimental five-level hybrid inverter test rig has been built using SiC switches to implement the proposed algorithm. Gating signals are generated using PIC microcontroller. The performance of the inverter has been analyzed and compared with the result obtained from theory and simulation. Simulation study of Proportional Integral (PI controller for the inverter employing the proposed modulation strategy has been done in MATLAB/SIMULINK. Keywords: Multilevel inverter, SiC , dual reference modulation, switching losses, PI

  5. Reference tissue modeling with parameter coupling: application to a study of SERT binding in HIV

    Energy Technology Data Exchange (ETDEWEB)

    Endres, Christopher J; Pomper, Martin G [Russell H Morgan Department of Radiology and Radiological Science, Johns Hopkins Medical Institutions, Baltimore, MD 21231 (United States); Hammoud, Dima A, E-mail: endres@jhmi.edu [Radiology and Imaging Sciences, National Institutes of Health/Clinical Center, Bethesda, MD (United States)

    2011-04-21

    When applicable, it is generally preferred to evaluate positron emission tomography (PET) studies using a reference tissue-based approach as that avoids the need for invasive arterial blood sampling. However, most reference tissue methods have been shown to have a bias that is dependent on the level of tracer binding, and the variability of parameter estimates may be substantially affected by noise level. In a study of serotonin transporter (SERT) binding in HIV dementia, it was determined that applying parameter coupling to the simplified reference tissue model (SRTM) reduced the variability of parameter estimates and yielded the strongest between-group significant differences in SERT binding. The use of parameter coupling makes the application of SRTM more consistent with conventional blood input models and reduces the total number of fitted parameters, thus should yield more robust parameter estimates. Here, we provide a detailed evaluation of the application of parameter constraint and parameter coupling to [{sup 11}C]DASB PET studies. Five quantitative methods, including three methods that constrain the reference tissue clearance (k{sup r}{sub 2}) to a common value across regions were applied to the clinical and simulated data to compare measurement of the tracer binding potential (BP{sub ND}). Compared with standard SRTM, either coupling of k{sup r}{sub 2} across regions or constraining k{sup r}{sub 2} to a first-pass estimate improved the sensitivity of SRTM to measuring a significant difference in BP{sub ND} between patients and controls. Parameter coupling was particularly effective in reducing the variance of parameter estimates, which was less than 50% of the variance obtained with standard SRTM. A linear approach was also improved when constraining k{sup r}{sub 2} to a first-pass estimate, although the SRTM-based methods yielded stronger significant differences when applied to the clinical study. This work shows that parameter coupling reduces the

  6. A High-voltage Reference Testbed for the Evaluation of High-voltage Dividers for Pulsed Applications

    CERN Document Server

    Bastos, M Cerqueira; Bergman, A; 10.1109/CPEM.2010.5543408

    2010-01-01

    The design, evaluation and commissioning of a high voltage reference testbed for pulsed applications to be used in the precision testing of high voltage dividers is described. The testbed is composed of a pulsed power supply, a reference divider based on compressed gas capacitor technology and an acquisition system which makes use of the fast measurement capabilities of the HP 3458 DVM. Results of the evaluation of the reference system are presented.

  7. State-specific Multi-reference Perturbation Theories with Relaxed Coefficients: Molecular Applications

    Directory of Open Access Journals (Sweden)

    Debashis Mukherjee

    2002-06-01

    Full Text Available Abstract: We present in this paper two new versions of Rayleigh-Schr¨odinger (RS and the Brillouin-Wigner (BW state-specific multi-reference perturbative theories (SSMRPT which stem from our state-specific multi-reference coupled-cluster formalism (SS-MRCC, developed with a complete active space (CAS. They are manifestly sizeextensive and are designed to avoid intruders. The combining coefficients cμ for the model functions φμ are completely relaxed and are obtained by diagonalizing an effective operator in the model space, one root of which is the target eigenvalue of interest. By invoking suitable partitioning of the hamiltonian, very convenient perturbative versions of the formalism in both the RS and the BW forms are developed for the second order energy. The unperturbed hamiltonians for these theories can be chosen to be of both Mφller-Plesset (MP and Epstein-Nesbet (EN type. However, we choose the corresponding Fock operator fμ for each model function φμ, whose diagonal elements are used to define the unperturbed hamiltonian in the MP partition. In the EN partition, we additionally include all the diagonal direct and exchange ladders. Our SS-MRPT thus utilizes a multi-partitioning strategy. Illustrative numerical applications are presented for potential energy surfaces (PES of the ground (1Σ+ and the first delta (1Δ states of CH+ which possess pronounced multi-reference character. Comparison of the results with the corresponding full CI values indicates the efficacy of our formalisms.

  8. 43 CFR 20.101 - Cross-references to ethical conduct, financial disclosure and other applicable regulations.

    Science.gov (United States)

    2010-10-01

    ..., financial disclosure and other applicable regulations. 20.101 Section 20.101 Public Lands: Interior Office... Cross-references to ethical conduct, financial disclosure and other applicable regulations. In addition... responsibilities and conduct regulations at 5 CFR part 735; and the executive branch financial...

  9. 15 CFR 0.735-2 - Cross-references to ethical conduct, financial disclosure, and other applicable regulations.

    Science.gov (United States)

    2010-01-01

    ..., financial disclosure, and other applicable regulations. 0.735-2 Section 0.735-2 Commerce and Foreign Trade... Cross-references to ethical conduct, financial disclosure, and other applicable regulations. Employees... at 5 CFR part 2635 and the executive branch-wide financial disclosure regulations at 5 CFR part 2634....

  10. 14 CFR 1207.101 - Cross-references to ethical conduct, financial disclosure, and other applicable regulations.

    Science.gov (United States)

    2010-01-01

    ..., financial disclosure, and other applicable regulations. 1207.101 Section 1207.101 Aeronautics and Space...-references to ethical conduct, financial disclosure, and other applicable regulations. Employees of the... and conduct at 5 CFR part 735, and the executive branch-wide financial disclosure regulation at 5...

  11. Applicability of the "Frame of Reference" approach for environmental monitoring of offshore renewable energy projects.

    Science.gov (United States)

    Garel, Erwan; Rey, Cibran Camba; Ferreira, Oscar; van Koningsveld, Mark

    2014-08-01

    This paper assesses the applicability of the Frame of Reference (FoR) approach for the environmental monitoring of large-scale offshore Marine Renewable Energy (MRE) projects. The focus is on projects harvesting energy from winds, waves and currents. Environmental concerns induced by MRE projects are reported based on a classification scheme identifying stressors, receptors, effects and impacts. Although the potential effects of stressors on most receptors are identified, there are large knowledge gaps regarding the corresponding (positive and negative) impacts. In that context, the development of offshore MRE requires the implementation of fit-for-purpose monitoring activities aimed at environmental protection and knowledge development. Taking European legislation as an example, it is suggested to adopt standardized monitoring protocols for the enhanced usage and utility of environmental indicators. Towards this objective, the use of the FoR approach is advocated since it provides guidance for the definition and use of coherent set of environmental state indicators. After a description of this framework, various examples of applications are provided considering a virtual MRE project located in European waters. Finally, some conclusions and recommendations are provided for the successful implementation of the FoR approach and for future studies.

  12. A Reference Model for Monitoring IoT WSN-Based Applications.

    Science.gov (United States)

    Capella, Juan Vicente; Campelo, José Carlos; Bonastre, Alberto; Ors, Rafael

    2016-10-30

    The Internet of Things (IoT) is, at this moment, one of the most promising technologies that has arisen for decades. Wireless Sensor Networks (WSNs) are one of the main pillars for many IoT applications, insofar as they require to obtain context-awareness information. The bibliography shows many difficulties in their real implementation that have prevented its massive deployment. Additionally, in IoT environments where data producers and data consumers are not directly related, compatibility and certification issues become fundamental. Both problems would profit from accurate knowledge of the internal behavior of WSNs that must be obtained by the utilization of appropriate tools. There are many ad-hoc proposals with no common structure or methodology, and intended to monitor a particular WSN. To overcome this problem, this paper proposes a structured three-layer reference model for WSN Monitoring Platforms (WSN-MP), which offers a standard environment for the design of new monitoring platforms to debug, verify and certify a WSN's behavior and performance, and applicable to every WSN. This model also allows the comparative analysis of the current proposals for monitoring the operation of WSNs. Following this methodology, it is possible to achieve a standardization of WSN-MP, promoting new research areas in order to solve the problems of each layer.

  13. Bayesian methods for uncertainty factor application for derivation of reference values.

    Science.gov (United States)

    Simon, Ted W; Zhu, Yiliang; Dourson, Michael L; Beck, Nancy B

    2016-10-01

    In 2014, the National Research Council (NRC) published Review of EPA's Integrated Risk Information System (IRIS) Process that considers methods EPA uses for developing toxicity criteria for non-carcinogens. These criteria are the Reference Dose (RfD) for oral exposure and Reference Concentration (RfC) for inhalation exposure. The NRC Review suggested using Bayesian methods for application of uncertainty factors (UFs) to adjust the point of departure dose or concentration to a level considered to be without adverse effects for the human population. The NRC foresaw Bayesian methods would be potentially useful for combining toxicity data from disparate sources-high throughput assays, animal testing, and observational epidemiology. UFs represent five distinct areas for which both adjustment and consideration of uncertainty may be needed. NRC suggested UFs could be represented as Bayesian prior distributions, illustrated the use of a log-normal distribution to represent the composite UF, and combined this distribution with a log-normal distribution representing uncertainty in the point of departure (POD) to reflect the overall uncertainty. Here, we explore these suggestions and present a refinement of the methodology suggested by NRC that considers each individual UF as a distribution. From an examination of 24 evaluations from EPA's IRIS program, when individual UFs were represented using this approach, the geometric mean fold change in the value of the RfD or RfC increased from 3 to over 30, depending on the number of individual UFs used and the sophistication of the assessment. We present example calculations and recommendations for implementing the refined NRC methodology.

  14. IFCC recommendation: The theory of reference values. Part 4. Control of analytical variation in the production, transfer and application of reference values

    OpenAIRE

    Solberg, Helge Erik; Stamm, D.

    1991-01-01

    This paper is the fourth in a series of Recommendations on the Theory of Reference Values. The others cover: Part 1. The Concept of Reference Values [1]. Part 2. Selection of Individuals for the Production of Reference Values [2]. Part 3. Preparation of Individuals and Collection of Specimens for the Production of Reference Values [3]. Part 5. Statistical Treatment of Collected Reference Values. Determination of Reference Limits [4]. Part 6. Presentation of Observed Values Related to Referenc...

  15. Standard Reference Tables -

    Data.gov (United States)

    Department of Transportation — The Standard Reference Tables (SRT) provide consistent reference data for the various applications that support Flight Standards Service (AFS) business processes and...

  16. Applicability of Two International Risk Scores in Cardiac Surgery in a Reference Center in Brazil

    Energy Technology Data Exchange (ETDEWEB)

    Garofallo, Silvia Bueno; Machado, Daniel Pinheiro; Rodrigues, Clarissa Garcia; Bordim, Odemir Jr.; Kalil, Renato A. K.; Portal, Vera Lúcia, E-mail: veraportal.pesquisa@gmail.com [Post-Graduation Program in Health Sciences: Cardiology, Instituto de Cardiologia/Fundação Universitária de Cardiologia, Porto Alegre, RS (Brazil)

    2014-06-15

    The applicability of international risk scores in heart surgery (HS) is not well defined in centers outside of North America and Europe. To evaluate the capacity of the Parsonnet Bernstein 2000 (BP) and EuroSCORE (ES) in predicting in-hospital mortality (IHM) in patients undergoing HS at a reference hospital in Brazil and to identify risk predictors (RP). Retrospective cohort study of 1,065 patients, with 60.3% patients underwent coronary artery bypass grafting (CABG), 32.7%, valve surgery and 7.0%, CABG combined with valve surgery. Additive and logistic scores models, the area under the ROC (Receiver Operating Characteristic) curve (AUC) and the standardized mortality ratio (SMR) were calculated. Multivariate logistic regression was performed to identify the RP. Overall mortality was 7.8%. The baseline characteristics of the patients were significantly different in relation to BP and ES. AUCs of the logistic and additive BP were 0.72 (95% CI, from 0.66 to 0.78 p = 0.74), and of ES they were 0.73 (95% CI; 0.67 to 0.79 p = 0.80). The calculation of the SMR in BP was 1.59 (95% CI; 1.27 to 1.99) and in ES, 1.43 (95% CI; 1.14 to 1.79). Seven RP of IHM were identified: age, serum creatinine > 2.26 mg/dL, active endocarditis, systolic pulmonary arterial pressure > 60 mmHg, one or more previous HS, CABG combined with valve surgery and diabetes mellitus. Local scores, based on the real situation of local populations, must be developed for better assessment of risk in cardiac surgery.

  17. CMOS compatible fabrication process of MEMS resonator for timing reference and sensing application

    Science.gov (United States)

    Huynh, Duc H.; Nguyen, Phuong D.; Nguyen, Thanh C.; Skafidas, Stan; Evans, Robin

    2015-12-01

    Frequency reference and timing control devices are ubiquitous in electronic applications. There is at least one resonator required for each of this device. Currently electromechanical resonators such as crystal resonator, ceramic resonator are the ultimate choices. This tendency will probably keep going for many more years. However, current market demands for small size, low power consumption, cheap and reliable products, has divulged many limitations of this type of resonators. They cannot be integrated into standard CMOS (Complement metaloxide- semiconductor) IC (Integrated Circuit) due to material and fabrication process incompatibility. Currently, these devices are off-chip and they require external circuitries to interface with the ICs. This configuration significantly increases the overall size and cost of the entire electronic system. In addition, extra external connection, especially at high frequency, will potentially create negative impacts on the performance of the entire system due to signal degradation and parasitic effects. Furthermore, due to off-chip packaging nature, these devices are quite expensive, particularly for high frequency and high quality factor devices. To address these issues, researchers have been intensively studying on an alternative for type of resonator by utilizing the new emerging MEMS (Micro-electro-mechanical systems) technology. Recent progress in this field has demonstrated a MEMS resonator with resonant frequency of 2.97 GHz and quality factor (measured in vacuum) of 42900. Despite this great achievement, this prototype is still far from being fully integrated into CMOS system due to incompatibility in fabrication process and its high series motional impedance. On the other hand, fully integrated MEMS resonator had been demonstrated but at lower frequency and quality factor. We propose a design and fabrication process for a low cost, high frequency and a high quality MEMS resonator, which can be integrated into a standard

  18. Application of Optical Flow Sensors for Dead Reckoning, Heading Reference, Obstacle Detection, and Obstacle Avoidance

    Science.gov (United States)

    2015-09-01

    OPTICAL FLOW SENSORS FOR DEAD RECKONING, HEADING REFERENCE, OBSTACLE DETECTION, AND OBSTACLE AVOIDANCE by Tarek M. Nejah September 2015... SENSORS FOR DEAD RECKONING, HEADING REFERENCE, OBSTACLE DETECTION, AND OBSTACLE AVOIDANCE 5. FUNDING NUMBERS 6. AUTHOR(S) Nejah, Tarek M. 7...avoidance using only one optical mouse sensor was presented in this thesis. Odometry, position tracking, and obstacle avoidance are important issues in

  19. 40 CFR 53.4 - Applications for reference or equivalent method determinations.

    Science.gov (United States)

    2010-07-01

    ... A of this subpart, using appropriate graphical, nomenclature, and mathematical conventions such as... designated as a reference or equivalent method, to ensure that all analyzers or samplers offered for sale... tests are released for sale. (ii) Section 4.13 in reference 1 of appendix A of this subpart...

  20. Bushland Reference ET Calculator with QA/QC capabilities and iPhone/iPad application

    Science.gov (United States)

    Accurate daily reference evapotranspiration (ET) values are needed to estimate crop water demand for irrigation management and hydrologic modeling purposes. The USDA-ARS Conservation and Production Research Laboratory at Bushland, Texas developed the Bushland Reference ET (BET) Calculator for calcul...

  1. Application of the WHO Growth Reference (2007) to Assess the Nutritional Status of Children in China

    Institute of Scientific and Technical Information of China (English)

    YAN-PING LI; XIAO-QI HU; JING-ZHAO; XIAO-GUANG YANG; GUAN-SHENG MA

    2009-01-01

    Objective To assess the nutrition status of children and adolescents in China using the WHO growth reference (2007) in comparison with that defined by the International Obesity Task Force (IOTF) and the Working Group on Obesity in China (WGOC). Methods Overweight and obesity were defined by age-, sex-, specific BMI reference developed by WHO (2007), IOTF (2000), and WGOC (2004), respectively. Stunting and thinness were defined as height and BMI less than two standard deviations (SD) of the WHO growth reference (2007), respectively. Data of children and adolescents aged 5 to 19 years (n=54 857, 28 273 boys, 26 584 girls) from the 2002 China National Nutrition and Health Survey (CNNHS) were used in the study. Results The prevalence of overweight, obesity, stunting and thinness among Chinese children and adolescents aged 5-19 years was 5.0%, 1.2%, 13.8%, and 7.4%, respectively when the WHO growth reference (2007) was used, whereas the estimated absolute total number affected by these 4 conditions were 14.6, 3.7, 40.6, and 21.8 million, respectively. The prevalence of overweight and obesity was 18.1% in large cities, while the stunting prevalence was 25.1% in rural 4. Obesity prevalence assessed by the WHO growth reference was higher than that as assessed by the IOTF reference, and obesity prevalence assessed by the WGOC reference was lower than that as assessed by the IOTF reference. Conclusion The nutritional status of children and adolescents is not equal in different areas of China. Stunting is still the main health problem of the poor, while overweight and obesity are the main health problems in large cities.

  2. A reference system for animal biometrics: application to the northern leopard frog

    Science.gov (United States)

    Petrovska-Delacretaz, D.; Edwards, A.; Chiasson, J.; Chollet, G.; Pilliod, D.S.

    2014-01-01

    Reference systems and public databases are available for human biometrics, but to our knowledge nothing is available for animal biometrics. This is surprising because animals are not required to give their agreement to be in a database. This paper proposes a reference system and database for the northern leopard frog (Lithobates pipiens). Both are available for reproducible experiments. Results of both open set and closed set experiments are given.

  3. A Contrastive Study of Personal Reference between Chinese and English and Its Application

    Institute of Scientific and Technical Information of China (English)

    张茜

    2008-01-01

    This paper aims to make a contrast of personal reference between Chinese and English and apply the contrastive study to Second Language(L2)teaching and learning and English-Chinese translation.Both Chinese and English have certain expressions serving as personal reference so as to achieve unity and coherence of a text.In spite of the similarity,there are differences in grammatical devices of personal reference between the two languages.Generally speaking,compared with English,there are two main differences in Chinese:A:Native Chinese speakers are prone to omit the subject and possessive determiners.B:Native Chinese speakers usually employ the device of lexical repetition to achieve the unity and coherence of a text.Both the differences will cause difficulties in L2 learning and translation.

  4. Standard digital reference images for investment steel castings for aerospace applications

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 The digital reference images provided in the adjunct to this standard illustrate various types and degrees of discontinuities occurring in thin-wall steel investment castings. Use of this standard for the specification or grading of castings requires procurement of the adjunct digital reference images which illustrate the discontinuity types and severity levels. They are intended to provide the following: 1.1.1 A guide enabling recognition of thin-wall steel casting discontinuities and their differentiation both as to type and degree through digital radiographic examination. 1.1.2 Example digital radiographic illustrations of discontinuities and a nomenclature for reference in acceptance standards, specifications and drawings. 1.2 Two illustration categories are covered as follows: 1.2.1 Graded—Six common discontinuity types each illustrated in eight degrees of progressively increasing severity. 1.2.2 Ungraded—Twelve single illustrations of additional discontinuity types and of patterns and imper...

  5. Liver Rapid Reference Set Application (#1): David Lubman - Univ of Michigan (2009) — EDRN Public Portal

    Science.gov (United States)

    We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC for the 5 glycoproteins was 0.81. The sensitivity and specificity for the 5 glycoproteins was 79% and 72% at the point that maximizes sensitivity+specificity in the ROC curve, and it was 79% and 35%, respectively, for AFP at the same point in the ROC curve. The reference set will allow us to determine the best performance of the 5 glycoproteins by themselves or whether their combination has a better sensitivity and/or specificity and AUROC. While a direct comparison with AFP will be made, the reference set will not allow a robust comparison due to the low sample size. If the glycoproteins are complementary or have better performance than AFP, then the next step would be to test them in the entire phase 2 hepatocellular carcinoma set.

  6. Liver Rapid Reference Set Application ( #2): Lubman - Univ of Michigan (2010) — EDRN Public Portal

    Science.gov (United States)

    We are requesting the reference set, which includes 50 HCC cases and 50 cirrhotic controls. In our preliminary study, AFP had a AUROC of 0.66 while the AUROC for the 5 glycoproteins was 0.81. The sensitivity and specificity for the 5 glycoproteins was 79% and 72% at the point that maximizes sensitivity+specificity in the ROC curve, and it was 79% and 35%, respectively, for AFP at the same point in the ROC curve. The reference set will allow us to determine the best performance of the 5 glycoproteins by themselves or whether their combination has a better sensitivity and/or specificity and AUROC. While a direct comparison with AFP will be made, the reference set will not allow a robust comparison due to the low sample size. If the glycoproteins are complementary or have better performance than AFP, then the next step would be to test them in the entire phase 2 hepatocellular carcinoma set.

  7. Composite iterative learning controller design for gradually varying references with applications in an AFM system

    Institute of Scientific and Technical Information of China (English)

    方勇纯; 张玉东; 董晓坤

    2014-01-01

    Learning control for gradually varying references in iteration domain was considered in this research, and a composite iterative learning control strategy was proposed to enable a plant to track unknown iteration-dependent trajectories. Specifically, by decoupling the current reference into the desired trajectory of the last trial and a disturbance signal with small magnitude, the learning and feedback parts were designed respectively to ensure fine tracking performance. After some theoretical analysis, the judging condition on whether the composite iterative learning control approach achieves better control results than pure feedback control was obtained for varying references. The convergence property of the closed-loop system was rigorously studied and the saturation problem was also addressed in the controller. The designed composite iterative learning control strategy is successfully employed in an atomic force microscope system, with both simulation and experimental results clearly demonstrating its superior performance.

  8. Chronically Implanted, Nafion-Coated Ag/AgCl Reference Electrodes for Neurochemical Applications.

    Science.gov (United States)

    Hashemi, Parastoo; Walsh, Paul L; Guillot, Thomas S; Gras-Najjar, Julie; Takmakov, Pavel; Crews, Fulton T; Wightman, R Mark

    2011-11-16

    Fast-scan cyclic voltammetry (FSCV) at carbon fiber microelectrodes can be used to measure behaviorally correlated dopamine changes in the extracellular fluid of the brain of freely moving rats. These experiments employ a chronically implanted Ag/AgCl reference electrode. When dopamine measurements are taken 4 days after implantation, there is often a potential shift, typically greater than +0.2 V, in the anodic and cathodic peaks in the cyclic voltammogram for dopamine. In this work, we optimized a method to coat sintered Ag/AgCl reference electrodes with the perfluorinated polymer, Nafion, to prevent this shift. We find that we can stabilize reference electrodes for up to 28 days. Immunohistochemistry of the tissue around the implant site shows extensive glial encapsulation around both bare and Nafion-coated devices. However, the lesion around bare electrodes has a rough texture implying that these cells are strongly adsorbed onto the bare reference electrode, while the lesion around a Nafion-coated electrode shows that cells are more intact implying that they adsorb less strongly. EDS and SEM analysis of the surface of the electrodes confirms this by visualizing a heavy build up of plaques, organic in nature, only on bare electrodes. Impedance spectroscopy indicates no difference between the impedance of bare and Nafion-coated Ag/AgCl electrodes, indicating that glial encapsulation does not lead to an increase in uncompensated resistance between the working and reference electrodes. The electrochemical shift therefore must be due to the unique chemical microenvironment around the reference electrode that alters the chloride equilibrium, a process that the Nafion coating prevents.

  9. 40 CFR Table A-1 to Subpart A of... - Summary of Applicable Requirements for Reference and Equivalent Methods for Air Monitoring of...

    Science.gov (United States)

    2010-07-01

    ... Reference and Equivalent Methods for Air Monitoring of Criteria Pollutants A Table A-1 to Subpart A of Part...) AMBIENT AIR MONITORING REFERENCE AND EQUIVALENT METHODS General Provisions Pt. 53, Subpt. A, Table A-1 Table A-1 to Subpart A of Part 53—Summary of Applicable Requirements for Reference and...

  10. CCF analysis of high redundancy systems safety/relief valve data analysis and reference BWR application. Main report

    Energy Technology Data Exchange (ETDEWEB)

    Mankamo, T. [Avaplan Oy (Finland); Bjoere, S.; Olsson, Lena [ABB Atom AB, Vaesteraas (Sweden)

    1992-12-01

    Dependent failure analysis and modeling were developed for high redundancy systems. The study included a comprehensive data analysis of safety and relief valves at the Finnish and Swedish BWR plants, resulting in improved understanding of Common Cause Failure mechanisms in these components. The reference application on the Forsmark 1/2 reactor relief system, constituting of twelve safety/relief lines and two regulating relief lines, covered different safety criteria cases of reactor depressurization and overpressure protection function, and failure to re close sequences. For the quantification of dependencies, the Alpha Factor Model, the Binomial Probability Model and the Common Load Model were compared for applicability in high redundancy systems.

  11. A computational model for reference-frame synthesis with applications to motion perception.

    Science.gov (United States)

    Clarke, Aaron M; Öğmen, Haluk; Herzog, Michael H

    2016-09-01

    As discovered by the Gestaltists, in particular by Duncker, we often perceive motion to be within a non-retinotopic reference frame. For example, the motion of a reflector on a bicycle appears to be circular, whereas, it traces out a cycloidal path with respect to external world coordinates. The reflector motion appears to be circular because the human brain subtracts the horizontal motion of the bicycle from the reflector motion. The bicycle serves as a reference frame for the reflector motion. Here, we present a general mathematical framework, based on vector fields, to explain non-retinotopic motion processing. Using four types of non-retinotopic motion paradigms, we show how the theory works in detail. For example, we show how non-retinotopic motion in the Ternus-Pikler display can be computed.

  12. Salivary cortisol monitoring: determination of reference values in healthy children and application in asthmatic children.

    Science.gov (United States)

    Nagakura, Toshikazu; Tanaka, Toshiaki; Arita, Masahiko; Nishikawa, Kiyoshi; Shigeta, Makoto; Wada, Noriyuki; Matsumoto, Tsutomu; Hiraba, Kazumi; Fukuda, Norimasa

    2012-01-01

    Venipuncture testing of adrenocortical function in asthmatic infants and young children receiving inhaled corticosteroids can raise cortisol levels and mask physiological responses. This study aimed to establish reference ranges for salivary cortisol levels and evaluate the safety and effects of jet-nebulized budesonide inhalation suspension (BIS) on salivary cortisol levels and patient outcomes in infants and young children with mild or persistent asthma. Reference salivary cortisol levels were determined in healthy children aged 6 months to 4 years old. A 12-week multicenter, randomized, parallel-group, open-label study was performed involving 53 age-matched asthmatic children who received either 0.5 mg/day of BIS or 40-60 mg/day of cromolyn sodium inhalation suspension (CIS) via compressor nebulizer. The effective measuring range of salivary cortisol concentration in asthmatic children was 0.12-3.00 micrograms/dL. The upper and lower limits of the reference range were 0.827 and 0.076 micrograms/dL, respectively. No significant difference was seen from baseline through week 12 in the CIS and BIS groups. BIS was safe in these patients, with no inhibitory effects on adrenocortical function. Salivary cortisol measurement offers a useful and accurate tool for testing adrenocortical function in infants and young children. Longer-term studies that incorporate testing of the hypothalamic-pituitary-adrenal axis are warranted to confirm our findings.

  13. Development and application of a general plasmid reference material for GMO screening.

    Science.gov (United States)

    Wu, Yuhua; Li, Jun; Wang, Yulei; Li, Xiaofei; Li, Yunjing; Zhu, Li; Li, Jun; Wu, Gang

    The use of analytical controls is essential when performing GMO detection through screening tests. Additionally, the presence of taxon-specific sequences is analyzed mostly for quality control during GMO detection. In this study, 11 commonly used genetic elements involving three promoters (P-35S, P-FMV35S and P-NOS), four marker genes (Bar, NPTII, HPT and Pmi), and four terminators (T-NOS, T-35S, T-g7 and T-e9), together with the reference gene fragments from six major crops of maize, soybean, rapeseed, rice, cotton and wheat, were co-integrated into the same single plasmid to construct a general reference plasmid pBI121-Screening. The suitability test of pBI121-Screening plasmid as reference material indicated that the non-target sequence on the pBI121-Screening plasmid did not affect the PCR amplification efficiencies of screening methods and taxon-specific methods. The sensitivity of screening and taxon-specific assays ranged from 5 to 10 copies of pBI121-Screening plasmid, meeting the sensitivity requirement of GMO detection. The construction of pBI121-Screening solves the lack of a general positive control for screening tests, thereby reducing the workload and cost of preparing a plurality of the positive control.

  14. Reference Standardization for Mass Spectrometry and High-resolution Metabolomics Applications to Exposome Research.

    Science.gov (United States)

    Go, Young-Mi; Walker, Douglas I; Liang, Yongliang; Uppal, Karan; Soltow, Quinlyn A; Tran, ViLinh; Strobel, Frederick; Quyyumi, Arshed A; Ziegler, Thomas R; Pennell, Kurt D; Miller, Gary W; Jones, Dean P

    2015-12-01

    The exposome is the cumulative measure of environmental influences and associated biological responses throughout the lifespan, including exposures from the environment, diet, behavior, and endogenous processes. A major challenge for exposome research lies in the development of robust and affordable analytic procedures to measure the broad range of exposures and associated biologic impacts occurring over a lifetime. Biomonitoring is an established approach to evaluate internal body burden of environmental exposures, but use of biomonitoring for exposome research is often limited by the high costs associated with quantification of individual chemicals. High-resolution metabolomics (HRM) uses ultra-high resolution mass spectrometry with minimal sample preparation to support high-throughput relative quantification of thousands of environmental, dietary, and microbial chemicals. HRM also measures metabolites in most endogenous metabolic pathways, thereby providing simultaneous measurement of biologic responses to environmental exposures. The present research examined quantification strategies to enhance the usefulness of HRM data for cumulative exposome research. The results provide a simple reference standardization protocol in which individual chemical concentrations in unknown samples are estimated by comparison to a concurrently analyzed, pooled reference sample with known chemical concentrations. The approach was tested using blinded analyses of amino acids in human samples and was found to be comparable to independent laboratory results based on surrogate standardization or internal standardization. Quantification was reproducible over a 13-month period and extrapolated to thousands of chemicals. The results show that reference standardization protocol provides an effective strategy that will enhance data collection for cumulative exposome research. In principle, the approach can be extended to other types of mass spectrometry and other analytical methods.

  15. Applications of dendrochronology and sediment geochronology to establish reference episodes for evaluations of environmental radioactivity

    Energy Technology Data Exchange (ETDEWEB)

    Waugh, W.J.; Carroll, J.; Abraham, J.D.; Landeen, D.S. [Roy F. Weston, Inc., U.S. Department of Energy, Grand Junction Office, 2597 B 3/4 Road, Grand Junction, CO 81503 (United States)

    1998-12-01

    Dendrochronology and sediment geochronology have been used to demonstrate retrospective monitoring of environmental radioactivity at United States Department of Energy (DOE) sites. {sup 14}C in annual growth rings of sagebrush preserved the temporal and spatial patterns of {sup 14}C resulting from dispersion downwind of a nuclear fuel processing facility at the Hanford Site in Washington State. As far as 10 km downwind of the facility, {sup 14}C concentrations were significantly higher in growth rings formed during a fuel processing episode than in rings produced during preoperational or postoperational episodes. An episode of uranium mill tailings deposition in pond sediments at the Grand Junction Office in Colorado was reconstructed using {sup 210}Pb geochronology constrained by a marker of peak {sup 137}Cs fallout. Uranium concentrations in ponds sediments deposited after the processing episode provide a reasonable cleanup standard. These reference episodes of environmental radioactivity reconstructed from measurements taken within contaminated environments can improve or replace reference area data as baseline information for dose reconstructions, risk assessments, and the establishment of cleanup standards. (Copyright (c) 1998 Elsevier Science B.V., Amsterdam. All rights reserved.)

  16. Earth Global Reference Atmospheric Model 2007 (Earth-GRAM07) Applications for the NASA Constellation Program

    Science.gov (United States)

    Leslie, Fred W.; Justus, C. G.

    2008-01-01

    Engineering models of the atmosphere are used extensively by the aerospace community for design issues related to vehicle ascent and descent. The Earth Global Reference Atmosphere Model version 2007 (Earth-GRAM07) is the latest in this series and includes a number of new features. Like previous versions, Earth-GRAM07 provides both mean values and perturbations for density, temperature, pressure, and winds, as well as monthly- and geographically-varying trace constituent concentrations. From 0 km to 27 km, thermodynamics and winds are based on the National Oceanic and Atmospheric Administration Global Upper Air Climatic Atlas (GUACA) climatology. For altitudes between 20 km and 120 km, the model uses data from the Middle Atmosphere Program (MAP). Above 120 km, EarthGRAM07 now provides users with a choice of three thermosphere models: the Marshall Engineering Thermosphere (MET-2007) model; the Jacchia-Bowman 2006 thermosphere model (JB2006); and the Naval Research Labs Mass Spectrometer, Incoherent Scatter Radar Extended Model (NRL MSIS E-OO) with the associated Harmonic Wind Model (HWM-93). In place of these datasets, Earth-GRAM07 has the option of using the new 2006 revised Range Reference Atmosphere (RRA) data, the earlier (1983) RRA data, or the user may also provide their own data as an auxiliary profile. Refinements of the perturbation model are also discussed which include wind shears more similar to those observed at the Kennedy Space Center than the previous version Earth-GRAM99.

  17. Characterization of bandgap reference circuits designed for high energy physics applications

    Science.gov (United States)

    Traversi, G.; De Canio, F.; Gaioni, L.; Manghisoni, M.; Mattiazzo, S.; Ratti, L.; Re, V.; Riceputi, E.

    2016-07-01

    The objective of this work is to design a high performance bandgap voltage reference circuit in a standard commercial 65 nm CMOS technology capable of operating in harsh radiation environments. A prototype circuit based on three different devices (diode, bipolar transistor and MOSFET) was fabricated and tested. Measurement results show a temperature variation as low as ±3.4 mV over a temperature range of 170 ° C (-30 °C to 140 °C) and a line regulation at room temperature of 5.2%/V. Measured VREF is 690 mV±15 mV (3σ) for 26 samples on the same wafer. Circuits correctly operate with supply voltages in the range from 1.32 V down to 0.78 V. A reference voltage shift of only 7.6 mV (around 1.1%) was measured after irradiation with 10 keV X-rays up to an integrated dose of 225 Mrad (SiO2).

  18. RBE, reference RBE and clinical RBE: applications of these concepts in hadron therapy.

    Science.gov (United States)

    Wambersie, A

    1999-06-01

    Introduction of heavy particles (hadrons) into radiation therapy aims at improving the physical selectivity of the irradiation (e.g. proton beams), or the radiobiological differential effect (e.g. fast neutrons), or both (e.g. heavy-ion beams). Each of these new therapy modalities requires several types of information before prescribing safely the doses to patients, as well as for recording and reporting the treatments: (i) absorbed dose measured in a homogeneous phantom in reference conditions; (ii) dose distribution computed at the level of the target volume(s) and the normal tissues at risk; (iii) radiation quality from which a RBE evaluation could be predicted and (iv) RBE measured on biological systems or derived from clinical observation. In hadron therapy, the RBE of the different beams raises specific problems. For fast neutrons, the RBE varies within wide limits (about 2 to 5) depending on the neutron energy spectrum, dose, and biological system. For protons, the RBE values range between smaller limits (about 1.0 to 1.2). A clinical benefit can thus not be expected from RBE differences. However, the proton RBE problem cannot be ignored since dose differences of about 5% can be detected clinically in some cases. The situation is most complex with heavy ions since RBE variations are at least as large as for fast neutrons, as a function of particle type and energy, dose and biological system. In addition, RBE varies with depth. Radiation quality thus has to be taken into account when prescribing and reporting a treatment. This can be done in different ways: (a) description of the method of beam production; (b) computed LET spectra and/or measured microdosimetric spectra at the points clinically relevant; (c) RBE determination. The most relevant RBE data are those obtained for late tolerance of normal tissues at 2 Gy per fraction ("reference RBE"). The "clinical RBE" selected by the radiation oncologist when prescribing the treatment will be close to the

  19. Toxicity reference values for chlorophacinone and their application for assessing anticoagulant rodenticide risk to raptors

    Science.gov (United States)

    Rattner, Barnett A.; Horak, Katherine E.; Lazarus, Rebecca; Schultz, Sandra; Knowles, Susan N.; Abbo, B.G.; Volker, Steven F.

    2015-01-01

    Despite widespread use and benefit, there are growing concerns regarding hazards of second-generation anticoagulant rodenticides to non-target wildlife which may result in expanded use of first-generation compounds, including chlorophacinone (CPN). The toxicity of CPN over a 7-day exposure period was investigated in American kestrels (Falco sparverius) fed either rat tissue mechanically-amended with CPN, tissue from rats fed Rozol® bait (biologically-incorporated CPN), or control diets (tissue from untreated rats or commercial bird of prey diet) ad libitum. Nominal CPN concentrations in the formulated diets were 0.15, 0.75 and 1.5 µg/g food wet weight, and measured concentrations averaged 94 % of target values. Kestrel food consumption was similar among groups and body weight varied by less than 6 %. Overt signs of intoxication, liver CPN residues, and changes in prothrombin time (PT), Russell’s viper venom time (RVVT) and hematocrit, were generally dose-dependent. Histological evidence of hemorrhage was present at all CPN dose levels, and most frequently observed in pectoral muscle and heart. There were no apparent differences in toxicity between mechanically-amended and biologically-incorporated CPN diet formulations. Dietary-based toxicity reference values at which clotting times were prolonged in 50 % of the kestrels were 79.2 µg CPN consumed/kg body weight-day for PT and 39.1 µg/kg body weight-day for RVVT. Based upon daily food consumption of kestrels and previously reported CPN concentrations found in small mammals following field baiting trials, these toxicity reference values might be exceeded by free-ranging raptors consuming such exposed prey. Tissue-based toxicity reference values for coagulopathy in 50 % of exposed birds were 0.107 µg CPN/g liver wet weight for PT and 0.076 µg/g liver for RVVT, and are below the range of residue levels reported in raptor mortality incidents attributed to CPN exposure. Sublethal responses associated

  20. Liver Rapid Reference Set Application: Hemken - Abbott (2015) — EDRN Public Portal

    Science.gov (United States)

    The aim for this testing is to find a small panel of biomarkers (n=2-5) that can be tested on the Abbott ARCHITECT automated immunoassay platform for the early detection of hepatocellular carcinoma (HCC). This panel of biomarkers should perform significantly better than alpha-fetoprotein (AFP) alone based on multivariate statistical analysis. This testing of the EDRN reference set will help expedite the selection of a small panel of ARCHITECT biomarkers for the early detection of HCC. The panel of ARCHITECT biomarkers Abbott plans to test include: AFP, protein induced by vitamin K absence or antagonist-II (PIVKA-II), golgi protein 73 (GP73), hepatocellular growth factor (HGF), dipeptidyl peptidase 4 (DPP4) and DPP4/seprase (surface expressed protease) heterodimer hybrid. PIVKA-II is abnormal des-carboxylated prothrombin (DCP) present in vitamin K deficiency.

  1. An ultra-stable iodine-based frequency reference for space applications

    Science.gov (United States)

    Schuldt, Thilo; Braxmaier, Claus; Doeringshoff, Klaus; Keetman, Anja; Reggentin, Matthias; Kovalchuk, Evgeny; Peters, Achim

    2012-07-01

    Future space missions require for ultra-stable optical frequency references. Examples are the gravitational wave detector LISA/eLISA (Laser Interferometer Space Antenna), the SpaceTime Asymmetry Research (STAR) program, the aperture-synthesis telescope Darwin and the GRACE (Gravity Recovery and Climate Experiment) follow on mission exploring Earth's gravity. As high long-term frequency stability is required, lasers stabilized to atomic or molecular transitions are preferred, also offering an absolute frequency reference. Frequency stabilities in the 10 ^{-15} domains at longer integration times (up to several hours) are demonstrated in laboratory experiments using setups based on Doppler-free spectroscopy. Such setups with a frequency stability comparable to the hydrogen maser in the microwave domain, have the potential to be developed space compatible on a relatively short time scale. Here, we present the development of ultra-stable optical frequency references based on modulation-transfer spectroscopy of molecular iodine. Noise levels of 2\\cdot10 ^{-14} at an integration time of 1 s and below 3\\cdot10 ^{-15} at integration times between 100 s and 1000 s are demonstrated with a laboratory setup using an 80 cm long iodine cell in single-pass configuration in combination with a frequency-doubled Nd:YAG laser and standard optical components and optomechanic mounts. The frequency stability at longer integration times is (amongst other things) limited by the dimensional stability of the optical setup, i.e. by th pointing stability of the two counter-propagating beams overlapped in the iodine cell. With the goal of a future space compatible setup, a compact frequency standard on EBB (elegant breadboard) level was realized. The spectroscopy unit utilizes a baseplate made of Clearceram-HS, a glass ceramics with an ultra-low coefficient of thermal expansion of 2\\cdot10 ^{-8} K ^{-1}. The optical components are joint to the baseplate using adhesive bonding technology

  2. A RISK-AWARE BUSINESS PROCESS MANAGEMENT REFERENCE MODEL AND ITS APPLICATION IN AN EGYPTIAN UNIVERSITY

    Directory of Open Access Journals (Sweden)

    Mohamed H. Haggag

    2015-05-01

    Full Text Available Due to the environmental pressures on organizations, the demand on Business Process Management (BPM automation suites has increased. This led to the arising need for managing process-related risks. Therefore the management of risks in business processes has been the subject of many researches during the past few years. However, most of these researches focused mainly on one or two stages of the BPM life cycle and introduced a support for it. This paper aims to provide a reference model for Risk-Aware BPM which addresses the whole stages of the BPM life cycle, as well as some current techniques are listed for the implementation of this model. Additionally, a case study for a business process in an Egyptian university is introduced, in order to apply this model in real-world environment. The results will be analyzed and concluded.

  3. Liver Full Reference Set Application :Timothy Block - Drexel Univ (2010) — EDRN Public Portal

    Science.gov (United States)

    The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular carcinoma (HCC) in the background of liver cirrhosis. The use of the validation set would allow us to directly compare GP73 and fucosylated markers against AFP, AFP-L3 and DCP as well as test them in combination with these markers

  4. Liver Rapid Reference Set Application: Timothy Block - Drexel Univ (2008) — EDRN Public Portal

    Science.gov (United States)

    The goal of this application is to determine if the levels of serum GP73 and fucosylated kininogen/acute phase proteins can be used to detect hepatocellular carcinoma (HCC) in the background of liver cirrhosis. The use of the validation set would allow us to directly compare GP73 and fucosylated markers against AFP, AFP-L3 and DCP as well as test them in combination with these markers

  5. Bumpy Application of Utility Code for Genomic Inventions: With Special Reference to Express Sequence Tags

    Directory of Open Access Journals (Sweden)

    M R Sreenivasa Murthy

    2013-12-01

    Full Text Available Genomics, a new bough of biotechnology responsible for gene mapping has acquired a rapid significance in the field of patents. Brisk growth of patent filing in genomic subject matter is raising serious concerns about their utility from the perspective of societal benefit. Though the genomic related patent application qualifies the criterion of invention and non-obviousness in major instances, the inventors are unable to satisfy the utility criterion. Some instances such as patent application for ESTs have no utility at all. The patent regulators constructed various tests to deal with the situation such as specificity, substantiality (real world credibility tests etc. Hoverer, it is noteworthy that an attempt to uniform the standard of utility test for genomic inventions especially in the field of ESTs, cloning and creation of chimeras, has been made by America and Europe through specific regulations. Thus, the objective of this paper is firstly, to explain the importance of biotechnology and genomic inventions for mankind and significance of ESTs for future research. Secondly, to analyze the application of Utility code prior to the emergence of Utility code in America and Europe. Thirdly to scrutinize the Utility code in both countries and their implication on aftermath cases, and. fourthly and finally, to critically evaluate the both countries utility pathways in the light of societal benefit.

  6. A study on the application of statistics and information theory to problems of communication with special reference to radar

    Directory of Open Access Journals (Sweden)

    B. S. Raghuram

    1963-07-01

    Full Text Available Information theory, which originated in Tele-communication studies, is a branch of Mathematical statistics with many applications of statistical inference. The three fundamental problems are: (i Development of statistical measures of information capacity in a Communication system, (ii the transmission problem of information in a system, and (iii analytical study of reception from a statistical decision point of view. This paper is an attempt to present a comprehensive study of all three aspects. In addition, application of sequential analysis, specially with reference to radar signal detection and range estimation has been briefly discussed. Finally from the point of view of signal reception in the case of a radar, the problem has been considered as a statistical decision study. In conclusion, the computational problems as well as certain comparative studies have been briefly touched upon. Illustrative examples are given and graphs are shown wherever necessary.

  7. Adiabatic diesel engine component development: Reference engine for on-highway applications

    Science.gov (United States)

    Hakim, Nabil S.

    1986-01-01

    The main objectives were to select an advanced low heat rejection diesel reference engine (ADRE) and to carry out systems analysis and design. The ADRE concept selection consisted of: (1) rated point performance optimization; (2) study of various exhaust energy recovery scenarios; (3) components, systems and engine configuration studies; and (4) life cycle cost estimates of the ADRE economic worth. The resulting ADRE design proposed a reciprocator with many advanced features for the 1995 technology demonstration time frame. These included ceramic air gap insulated hot section structural components, high temperature tribology treatments, nonmechanical (camless) valve actuation systems, and elimination of the cylinder head gasket. ADRE system analysis and design resulted in more definition of the engine systems. These systems include: (1) electro-hydraulic valve actuation, (2) electronic common rail injection system; (3) engine electronic control; (4) power transfer for accessory drives and exhaust energy recovery systems; and (5) truck installation. Tribology and performance assessments were also carried out. Finite element and probability of survival analyses were undertaken for the ceramic low heat rejection component.

  8. Reference database of hypervariable genetic markers of Argentina: application for molecular anthropology and forensic casework.

    Science.gov (United States)

    Sala, A; Penacino, G; Carnese, R; Corach, D

    1999-06-01

    The population of Argentina is mostly composed of people of European ancestry. Aboriginal communities are at present very reduced in number and restricted to small geographically isolated patches. Three aboriginal communities, the Mapuche, Tehuelche and Wichi, were selected for short tandem repeat (STR) investigation. The metropolitan population of the city of Buenos Aires was analyzed, with both micro- and minisatellites. The minisatellite loci D1S7, D2S44, D4S139, D5S110, D8S358, D10S28, and D17S26 were typed on HaeIII-digested DNA obtained from unrelated individuals. D1S80 was typed by polymerase chain reaction (PCR). The autosomal STRs THO1, FABP, D6S366, CSF1PO, TPOX, F13A1, FES/FPS, vWA, MBPA/B, D16S539, D7S820, D13S317, and RENA4 and the sex chromosome STRs HPRTB, DYS385, DYS3891, DYS38911, DYS19, DYS390, DYS391, DYS392, DYS393 and YCAII were also investigated. As a by-product of our investigations, a reference database was created that is routinely used in forensic casework and paternity testing. STR allele frequency distributions are characterized by significant differences within and also between different populations. In contrast, the minisatellite bin distribution of the metropolitan population is not significantly different from other Caucasian populations.

  9. MSA Bladder Reference Set Application: Charles Rosser-Hawaii (2014) — EDRN Public Portal

    Science.gov (United States)

    The goal of this proposal is straightforward. We wish to assay in a discovery set, reference set from EDRN, both PAI-1 and ANG promoters and genes for mutations. Then the results will be confirmed in a test cohort comprised of DNA extracted from fresh frozen tissue (n = 80 BCa patients). DNA from matching buffy coat from these 80 patients will serve as control. Extracted RNA can be assessed for difference in transcription. Furthermore, matched voided urine samples from these 80 patients are available to assess protein levels of PAI-1 and ANG by ELISA in addition to assessing activity of PAI-1 and ANG. At the end, we will link any genetic alteration with changes in RNA, protein and protein activity level as well as clinical features (e.g., age, race, tobacco history, grade, stage and outcomes). This comprehensive study will allow us with certainty to state if there are mutations in the promoters and genes of PAI-1 and ANG that are functional and thus may lead to the growth advantage that we previously demonstrated in our experiments.

  10. Teledetection passive et processus decisionnel a reference spatiale: Application a l'aquaculture en milieu marin

    Science.gov (United States)

    Habbane, Mohamed

    L'objectif de cette etude est d'elaborer un processus decisionnel a reference spatiale (PDRS) pour la mariculture. Le PDRS est applique aux eaux cotieres de la baie des Chaleurs, dans le golfe du Saint-Laurent (Canada). Une carte preliminaire regionale d'indices du potentiel maricole, d'une limite de resolution spatiale de 1 kmsp2, est produite avec des parametres du niveau 1. Ces parametres englobent la temperature de l'eau de surface, extraite des images AVHRR, la salinite, les courants ainsi que les pigments chlorophylliens, quantifies a l'aide de mesures in situ. Les images AVHRR, prises en 1994, ont ete utiliees comme reference primaire pour selectionner des aires pouvant supporter une activite maricole sur la cote nord de la baie des Chaleurs. La temperature de surface extraite de ces images permet une analyse mesoechelle a la fois qualitative et quantitative des processus cotiers observes pendant la periode d'acquisition des donnees. Les autres donnees, soit la salinite, les courants et les concentrations en pigments chlorophylliens, sont analysees de facon a identifier la variabilite spatio-temporelle des caracteristiques des eaux de surface. L'ensemble des informations permet de produire une carte preliminaire regionale d'indices du potentiel maricole de la partie centrale de la baie des Chaleurs. Selon cet indice (defini entre 0 et 1), le secteur de potentiel aquicole de 0,5 a 0,75 s'etend sur une superficie d'environ 300 kmsp2. La localisation de cette aire potentielle est en accord avec les fortes concentrations en pigments chlrophylliens, presentant des conditions environnementales ideales a une haute productivite biologique. Par la suite la carte preliminaire est modifiee en tenant compte des parametres du niveau 2. Ces parametres sont la geomorphologie littorale, la bathymetrie, les sediments en suspension, les vents, les vagues, le debit d'eau douce, la glace marine, le carbone organique dissous, les aires de peche et les sources de pollution. Ces

  11. Embedded FPGA platform for fast steering mirror and optical inertial reference unit applications

    Science.gov (United States)

    Wasson, Steven; Morgan, Felix; Eckelkamp-Baker, Dan

    2011-05-01

    Applied Technology Associates (ATA) is developing a field-programmable gate array (FPGA) based processing platform to transition our state-of-the-art fast-steering mirrors (FSM's) and optical inertial reference units (OIRU's) from the laboratory environment to field operation. This platform offers an abundance of reconfigurable high-speed digital input/output (I/O) and parallel hardware-based processing resources in a compact size, weight, and power (SWaP) form factor with a path to a radiation-hardened version. The FPGA's high-speed I/O can be used to acquire sensor data and drive actuators with minimal latency while the FPGA's processing resources can efficiently realize signal processing and control algorithms with deterministic timing. These features allow high sampling rates between 20 KHz - 30 KHz. This will result in higher open-loop bandwidths in our FSM's and OIRU's. This will subsequently result in improved disturbance rejection in our FSM's and improved base motion jitter rejection in our OIRU's. This paper briefly presents the embedded system requirements of ATA's FSM's and OIRU's and the FPGA-based computational architecture derived to meet these requirements. It then describes the FPGA cores and embedded software that have been developed to efficiently realize interfacing, signal processing, and data collection tasks. Special attention is given to ATA's high-performance floating-point co-processor and innovative design approach that translates signal processing and control algorithms developed in MATLAB®/Simulink® into their equivalent implementation on the co-processor.

  12. Application of artificial intelligence to estimate the reference evapotranspiration in sub-humid Doon valley

    Science.gov (United States)

    Nema, Manish K.; Khare, Deepak; Chandniha, Surendra K.

    2017-03-01

    Estimation of evapotranspiration (ET) is an essential component of the hydrologic cycle, which is also requisite for efficient irrigation water management planning and hydro-meteorological studies at both the basin and catchment scales. There are about twenty well-established methods available for ET estimation which depends upon various meteorological parameters and assumptions. Most of these methods are physically based and need a variety of input data. The FAO-56 Penman-Monteith method (PM) for estimating reference evapotranspiration (ET0) is recommend for irrigation scheduling worldwide, because PM generally yields the best results under various climatic conditions. This study investigates the abilities of artificial neural networks (ANN) to improve the accuracy of monthly evaporation estimation in sub-humid climatic region of Dehradun. In the first part of the study, different ANN models, comprising various combinations of training function and number of neutrons were developed to estimate the ET0 and it has been compared with the Penman-Monteith (PM) ET0 as the ideal (observed) ET0. Various statistical approaches were considered to estimate the model performance, i.e. Coefficient of Correlation (r), Sum of Squared Errors, Root Mean Square Error, Nash-Sutcliffe Efficiency Index (NSE) and Mean Absolute Error. The ANN model with Levenberg-Marquardt training algorithm, single hidden layer and nine number of neutron schema was found the best predicting capabilities for the study station with Coefficient of Correlation (r) and NSE value of 0.996 and 0.991 for calibration period and 0.990 and 0.980 for validation period, respectively. In the subsequent part of the study, the trend analysis of ET0 time series revealed a rising trend in the month of March, and a falling trend during June to November, except August, with more than 90% significance level and the annual declining rate was found to 1.49 mm per year.

  13. Superconductors, analysis and applications, with special reference to the utilisation of bulk (Re)BCO materials

    Energy Technology Data Exchange (ETDEWEB)

    Coombs, T.A., E-mail: tac1000@cam.ac.u [University of Cambridge, Department of Engineering, Trumpington Street, Cambridge CB2 1PZ (United Kingdom)

    2010-11-01

    The Electrical Power and Energy Conversion (EPEC) superconductivity group at Cambridge University has been working on the application of superconductivity to large scale devices. This work is taking place over a range of areas which cover FCLs, motors and generators, SMES, accelerator magnets and MRI. The research is underpinned by advanced modelling techniques using both pure Critical State models and E-J models to analyse the behaviour of the superconductors. As part of the device design we are concentrating on the analysis of AC losses in complicated geometries such as are found in motor windings and the magnetisation of bulk superconductors to enable their full potential to be realised. We are interested in the full range of high-temperature superconductors and have measured and predicted the performance of YBCO, MgB{sub 2} and BSCCO at a range of temperatures and in wire, tape and bulk forms. This paper concentrates on recent work which includes: modelling of coils using formulations based on H and A. A critical state model for the analysis of coils in SMES; crossed field effects in bulk superconductors; a magnetic model together with experimental results which explain and describe the method of flux pumping whereby a bulk superconductor can be magnetised to a high flux density using a repeatedly applied field of low flux density and finally a new configuration for MRI magnets

  14. Nutrimetabonomics:applications for nutritional sciences, with specific reference to gut microbial interactions.

    Science.gov (United States)

    Claus, Sandrine P; Swann, Jonathan R

    2013-01-01

    Understanding the role of the diet in determining human health and disease is one major objective of modern nutrition. Mammalian biocomplexity necessitates the incorporation of systems biology technologies into contemporary nutritional research. Metabonomics is a powerful approach that simultaneously measures the low-molecular-weight compounds in a biological sample, enabling the metabolic status of a biological system to be characterized. Such biochemical profiles contain latent information relating to inherent parameters, such as the genotype, and environmental factors, including the diet and gut microbiota. Nutritional metabonomics, or nutrimetabonomics, is being increasingly applied to study molecular interactions between the diet and the global metabolic system. This review discusses three primary areas in which nutrimetabonomics has enjoyed successful application in nutritional research: the illumination of molecular relationships between nutrition and biochemical processes; elucidation of biomarker signatures of food components for use in dietary surveillance; and the study of complex trans-genomic interactions between the mammalian host and its resident gut microbiome. Finally, this review illustrates the potential for nutrimetabonomics in nutritional science as an indispensable tool to achieve personalized nutrition.

  15. Application of ESP for gas cleaning in cement industry--with reference to India.

    Science.gov (United States)

    Bapat, J D

    2001-02-16

    Electrostatic precipitators (ESP) are used for gas cleaning in almost every section of cement manufacture. Application of ESP is studied, keeping in view Indian conditions. The characterisation of dust emissions has been done for different units, such as rotary kiln and raw mill, alkali by-pass, clinker cooler, cement and coal mill, in terms of exit gas quantity, temperature, dew point, dust content and particle size. It is seen that all these characteristics have a wide range of variance. The ESP system must effectively deal with these variations. The fundamental analytical expression governing the performance of ESP, i.e. the Deutsch equation, and that for particle migration velocity, were analysed to predict the effect of major operating parameters, namely particle size, temperature and applied voltage. Whereas the migration velocity (and the efficiency) varies directly with the particle size, it is proportional to the square and square root of applied voltage and absolute temperature of the gas, respectively. The increase in efficiency due to temperature is not seen in dc based ESP, perhaps due to more pronounced negative effect on the applied voltage due to the increase in dust resistivity at higher temperatures. The effect of gas and dust characteristics on the collection efficiency of ESP, as seen in the industrial practice, is summarised. Some main process and design improvements effectively dealing with the problem of gas and dust characteristics have been discussed. These are gas conditioning, pulse energization, ESP-fabric filter (FF) combination, improved horizontal flow as well as open top ESP.Generally, gas conditioning entails higher operating and maintenance costs. Pulse energization allows the use of hot gas, besides reducing the dust emission and power consumption. The improved horizontal flow ESP has been successfully used in coal dust cleaning. The open top or vertical flow ESP has a limitation on collection efficiency as it provides for only

  16. Multi-product newsvendor problem with hybrid demand and its applications to ordering pharmaceutical reference standard materials

    Science.gov (United States)

    Wang, Dan; Qin, Zhongfeng

    2016-04-01

    Uncertainty is inherent in the newsvendor problem. Most of the existing literature is devoted to characterizing the uncertainty either by randomness or by fuzziness. However, in many cases, randomness and fuzziness simultaneously appear in the same problem. Motivated by this observation, we investigate the multi-product newsvendor problem by considering the demands as hybrid variables which are proposed to describe quantities with double uncertainties. According to the expected value criterion, we formulate an expected profit maximization model and convert it to a deterministic form when the chance distributions are given. We discuss two special cases of hybrid variable demands and give their chance distributions. Then we design hybrid simulation to estimate the chance distribution and use genetic algorithm to solve the proposed models. Finally, we proceed to present numerical examples of purchasing pharmaceutical reference standard materials to illustrate the applicability of our methodology and the effectiveness of genetic algorithm.

  17. Whether western normative laboratory values used for clinical diagnosis are applicable to Indian population? An overview on reference interval.

    Science.gov (United States)

    Malati, T

    2009-04-01

    Reference Intervals denote normative values related to laboratory parameters/analytes used by diagnostic centers for clinical diagnosis. International guidelines recommend that every country must establish reference intervals for healthy individuals belonging to a group of homogeneous population. Considering enormous racial and ethnic diversity of Indian population, it is mandatory to establish reference intervals specific to Indian population. The overview on reference interval describes why the national organizations in India need to initiate nationwide efforts to establish its own laboratory standards for apparently healthy reference individuals belonging to our polygenetic, polyethnic, polyracial, multilinguistic and multicultural predominantly rural and appreciable urban Indian population with varied dietary habits.

  18. Application of fundamental aquatic chemistry to the safety case and the role of thermodynamic reference data bases

    Energy Technology Data Exchange (ETDEWEB)

    Altmaier, Marcus; Gaona, Xavier; Fellhauer, David; Geckeis, Horst [Karlsruhe Institute of Technology, Eggenstein-Leopoldshafen (Germany). Inst. for Nuclear Waste Disposal

    2015-07-01

    All national and international programs developing a Nuclear Waste Disposal Safety Case have recognized the essential requirement of assessing aqueous (radionuclide) chemistry and establishing reliable thermodynamic databases. Long-term disposal of nuclear waste in deep underground repositories is the safest option to separate highly hazardous radionuclides from the environment. In order to predict the long-term performance of a repository for different evolution scenarios, the potentially relevant specific (geo)chemical systems are analyzed. This requires a detailed understanding of solubility, speciation and thermodynamics for all relevant components including radionuclides, and the availability of reliable thermodynamic data and databases as fundamental input for integral geochemical model calculations and hence PA. Radionuclide solubility and speciation strongly depend on chemical conditions (pH, E{sub h}, matrix electrolyte system and ionic strength) with additional factors like the presence of complexing ligands or temperature further impacting solution chemistry. As the fundamental chemical key processes are known and convincingly described by general laws of nature (→ solution thermodynamics), the long-term behavior of a repository system can be analyzed over geological timescales using geochemical tools. A key application of fundamental aquatic chemistry in the Safety Case is the determination of solubility limits (radionuclide source terms). Based upon fundamental chemical information (on solid phases, complexation reactions, activity coefficients, etc.), the maximum amount of radionuclides potentially dissolved in a given volume of solution and transported away from the repository, are quantified. A detailed understanding of radionuclide chemistry is also crucial for neighboring fields. For example, advanced mechanistic understanding and modeling of sorption processes at the solid liquid interphase, waste dissolution processes, secondary phase and

  19. Applicability of kDNA-PCR for routine diagnosis of American tegumentary leishmaniasis in a tertiary reference hospital.

    Science.gov (United States)

    Satow, Marcela M; Yamashiro-Kanashiro, Edite H; Rocha, Mussya C; Oyafuso, Luiza K; Soler, Rita C; Cotrim, Paulo C; Lindoso, José Angelo L

    2013-01-01

    This study evaluated the applicability of kDNA-PCR as a prospective routine diagnosis method for American tegumentary leishmaniasis (ATL) in patients from the Instituto de Infectologia Emílio Ribas (IIER), a reference center for infectious diseases in São Paulo - SP, Brazil. The kDNA-PCR method detected Leishmania DNA in 87.5% (112/128) of the clinically suspected ATL patients, while the traditional methods demonstrated the following percentages of positivity: 62.8% (49/78) for the Montenegro skin test, 61.8% (47/76) for direct investigation, and 19.3% (22/114) for in vitro culture. The molecular method was able to confirm the disease in samples considered negative or inconclusive by traditional laboratory methods, contributing to the final clinical diagnosis and therapy of ATL in this hospital. Thus, we strongly recommend the inclusion of kDNA-PCR amplification as an alternative diagnostic method for ATL, suggesting a new algorithm routine to be followed to help the diagnosis and treatment of ATL in IIER.

  20. APPLICABILITY OF kDNA-PCR FOR ROUTINE DIAGNOSIS OF AMERICAN TEGUMENTARY LEISHMANIASIS IN A TERTIARY REFERENCE HOSPITAL

    Directory of Open Access Journals (Sweden)

    Marcela M. Satow

    2013-12-01

    Full Text Available SUMMARY This study evaluated the applicability of kDNA-PCR as a prospective routine diagnosis method for American tegumentary leishmaniasis (ATL in patients from the Instituto de Infectologia Emílio Ribas (IIER, a reference center for infectious diseases in São Paulo - SP, Brazil. The kDNA-PCR method detected Leishmania DNA in 87.5% (112/128 of the clinically suspected ATL patients, while the traditional methods demonstrated the following percentages of positivity: 62.8% (49/78 for the Montenegro skin test, 61.8% (47/76 for direct investigation, and 19.3% (22/114 for in vitro culture. The molecular method was able to confirm the disease in samples considered negative or inconclusive by traditional laboratory methods, contributing to the final clinical diagnosis and therapy of ATL in this hospital. Thus, we strongly recommend the inclusion of kDNA-PCR amplification as an alternative diagnostic method for ATL, suggesting a new algorithm routine to be followed to help the diagnosis and treatment of ATL in IIER.

  1. A Simple method for reference crop evapotranspiration under non-advective conditions suitable for remote sensing applications

    Science.gov (United States)

    de Bruin, Henk A. R.; Trigo, Isabel F.; Bosveld, Fred C.; Fokke Meirink, Jan

    2015-04-01

    A method is presented to estimate daily reference crop evapotranspiration (ETo) under non-advective conditions from Meteosat Second Generation (MSG) imagery. For this purpose observations of Cabauw in the Netherlands have been analyzed. Due to the climatic conditions and the local water management at this site water stress is very rare, which makes this dataset ideal to assess ETo without advection. The findings of older studies are combined to arrive at a simple formula for ETo, requiring daily global radiation and air temperature as input only. The formula is validated against independent eddy-covariance measurements of actual evapotranspiration. The bias is 3 W m-2 and the root mean square error (RMSE) 7.6 W m-2. The applied Slob-de Bruin estimate of net radiation is tested separately, yielding a bias of 1.4 W m-2 and a RMSE of 9.6 W m-2. In a next step the measured global radiation has been replaced with MSG estimates. For ETo this resulted in a bias of 1.6 W m-2 and a RMSE of 11.7 W m-2. Based on arguments used by Schmidt (1915) a reasonably sound physical justification for the proposed ETo formula is presented. This justifies application of the results outside Cabauw. However, this applies to conditions where advection can be ignored. It is pointed out that in semi-arid regions local advection cannot be ignored. Finally, the ambiguousness of the formal definition of ETo given in the FAO Irrigation and Drainage Paper No. 56 is discussed.

  2. Real-time virtual reference service based on applicable artificial intelligence technologies:The début of the robot Xiaotu at Tsinghua University Library

    Institute of Scientific and Technical Information of China (English)

    Fei; YAO; Lei; JI; Chengyu; ZHANG; Wu; CHEN

    2011-01-01

    The adoption of applicable artificial intelligence technologies to library real-time virtual reference services is an innovative experimentation in one of the key areas of library services.Based on the open source software Artificial Linguistic Internet Computer Entity(A.L.I.C.E.)and a combined application of several other relevant supporting technologies for facilitating the use of the current existing library resources,Tsinghua University Library has recently developed a real-time smart talking robot,named Xiaotu,for the enhancement of its various service functions,such as reference services,book searching,Baidu Baike searching,self-directed learning,etc.The operation of Xiaotu is programmed into Renren website(a social networking website),which adds significantly an innovative feature to the modus operandi of the real-time virtual reference service at Tsinghua University Library.

  3. Implicit reference-based group-wise image registration and its application to structural and functional MRI.

    Science.gov (United States)

    Geng, Xiujuan; Christensen, Gary E; Gu, Hong; Ross, Thomas J; Yang, Yihong

    2009-10-01

    In this study, an implicit reference group-wise (IRG) registration with a small deformation, linear elastic model was used to jointly estimate correspondences between a set of MRI images. The performance of pair-wise and group-wise registration algorithms was evaluated for spatial normalization of structural and functional MRI data. Traditional spatial normalization is accomplished by group-to-reference (G2R) registration in which a group of images are registered pair-wise to a reference image. G2R registration is limited due to bias associated with selecting a reference image. In contrast, implicit reference group-wise (IRG) registration estimates correspondences between a group of images by jointly registering the images to an implicit reference corresponding to the group average. The implicit reference is estimated during IRG registration eliminating the bias associated with selecting a specific reference image. Registration performance was evaluated using segmented T1-weighted magnetic resonance images from the Nonrigid Image Registration Evaluation Project (NIREP), DTI and fMRI images. Implicit reference pair-wise (IRP) registration-a special case of IRG registration for two images-is shown to produce better relative overlap than IRG for pair-wise registration using the same small deformation, linear elastic registration model. However, IRP-G2R registration is shown to have significant transitivity error, i.e., significant inconsistencies between correspondences defined by different pair-wise transformations. In contrast, IRG registration produces consistent correspondence between images in a group at the cost of slightly reduced pair-wise RO accuracy compared to IRP-G2R. IRG spatial normalization of the fractional anisotropy (FA) maps of DTI is shown to have smaller FA variance compared with G2R methods using the same elastic registration model. Analyses of fMRI data sets with sensorimotor and visual tasks show that IRG registration, on average, increases the

  4. 37 CFR 1.78 - Claiming benefit of earlier filing date and cross-references to other applications.

    Science.gov (United States)

    2010-07-01

    ...-filed application must name as an inventor at least one inventor named in the later-filed application and disclose the named inventor's invention claimed in at least one claim of the later-filed... provisional applications, each prior-filed provisional application must name as an inventor at least...

  5. Reference Revolutions.

    Science.gov (United States)

    Mason, Marilyn Gell

    1998-01-01

    Describes developments in Online Computer Library Center (OCLC) electronic reference services. Presents a background on networked cataloging and the initial implementation of reference services by OCLC. Discusses the introduction of OCLC FirstSearch service, which today offers access to over 65 databases, future developments in integrated…

  6. The projection of a test genome onto a reference population and applications to humans and archaic hominins.

    Science.gov (United States)

    Yang, Melinda A; Harris, Kelley; Slatkin, Montgomery

    2014-12-01

    We introduce a method for comparing a test genome with numerous genomes from a reference population. Sites in the test genome are given a weight, w, that depends on the allele frequency, x, in the reference population. The projection of the test genome onto the reference population is the average weight for each x, [Formula: see text]. The weight is assigned in such a way that, if the test genome is a random sample from the reference population, then [Formula: see text]. Using analytic theory, numerical analysis, and simulations, we show how the projection depends on the time of population splitting, the history of admixture, and changes in past population size. The projection is sensitive to small amounts of past admixture, the direction of admixture, and admixture from a population not sampled (a ghost population). We compute the projections of several human and two archaic genomes onto three reference populations from the 1000 Genomes project-Europeans, Han Chinese, and Yoruba-and discuss the consistency of our analysis with previously published results for European and Yoruba demographic history. Including higher amounts of admixture between Europeans and Yoruba soon after their separation and low amounts of admixture more recently can resolve discrepancies between the projections and demographic inferences from some previous studies.

  7. Analyzing Virtual Reference Station for GPS surveying: experiments and applications in a test site of the northern Apennine (Italy.

    Directory of Open Access Journals (Sweden)

    G. Casula

    2008-06-01

    Full Text Available The availability of a GPS network of 10-20 km mean size, provides good topographical support for the measurement of ground displacements, even at a local scale such as a landslide. In particular, a series of multitemporal kinematic or rapid-static GPS acquisitions of a landslide allows a good characterization of its displacements if the measurements are referred to a GPS reference network. Nevertheless, a wider network formed by stations located at long distances, for example at several tens of kilometers, characterized by large spacing, can lead to results affected by high noise, degrading the accuracy of final point positions. In order to obtain an adequate GPS reference network, some virtual reference stations (VRSs can be introduced, even if a network refinement based on VRS cannot reach the same accuracy of a real local network. Some experiments, including measurements on a real landslide, have been performed in order to evaluate the performance of this technique. The results point out that the standard deviation of the obtained solutions is about two or three times larger than those which can be reached using a real local network.

  8. VizBin: an application for reference-independent visualization and human-augmented binning of metagenomic data

    NARCIS (Netherlands)

    Laczny, C.C.; Sternal, T.; Plugaru, V.; Gawron, P.; Atashpendar, A.; Margossian, H.H.; Coronado, S.; Van der Maaten, L.J.M.; Vlassis, N.; Wilmes, P.

    2015-01-01

    Background: Metagenomics is limited in its ability to link distinct microbial populations to genetic potential due to a current lack of representative isolate genome sequences. Reference-independent approaches, which exploit for example inherent genomic signatures for the clustering of metagenomic f

  9. ICRP Publication 116—the first ICRP/ICRU application of the male and female adult reference computational phantoms

    CERN Document Server

    Petoussi-Henss, Nina; Eckerman, Keith F; Endo, Akira; Hertel, Nolan; Hunt, John; Menzel, Hans G; Pelliccioni, Maurizio; Schlattl, Helmut; Zankl, Maria

    2014-01-01

    ICRP Publication 116 on `Conversion coefficients for radiological protection quantities for external radiation exposures', provides fluence-to-dose conversion coefficients for organ-absorbed doses and effective dose for various types of external exposures (ICRP 2010 ICRP Publication 116). The publication supersedes the ICRP Publication 74 (ICRP 1996 ICRP Publication 74, ICRU 1998 ICRU Report 57), including new particle types and expanding the energy ranges considered. The coefficients were calculated using the ICRP/ICRU computational phantoms (ICRP 2009 ICRP Publication 110) representing the reference adult male and reference adult female (ICRP 2002 ICRP Publication 89), together with a variety of Monte Carlo codes simulating the radiation transport in the body. Idealized whole-body irradiation from unidirectional and rotational parallel beams as well as isotropic irradiation was considered for a large variety of incident radiations and energy ranges. Comparison of the effective doses with operational quantit...

  10. Application of the light-shift effect to laser frequency stabilization with reference to a microwave frequency standard

    Energy Technology Data Exchange (ETDEWEB)

    Arditi, M. (Univ. of Paris, Orsay, France); Picque, J.L.

    1975-10-01

    A new method allowing laser frequency stabilization with reference to a microwave oscillator, independently of the laser intensity, is described. The method makes use of the dependence of the ground-state HF transition frequency on the optical radiation frequency in alkali atoms irradiated by quasi-resonant light. Preliminary experimental investigations are reported in the case of a cw CaAs diode laser tuned to the D2 absorption line in a cesium gas cell. The absolute laser frequency exhibited variations of 1.4 MHz rms around an average value determined to within 2 parts in 100 billions for a period of 5 min. The possibility of defining a cesium beam, reference wavelength connected with the time standard is discussed.

  11. Perturbational treatment of spin-orbit coupling for generally applicable high-level multi-reference methods

    CERN Document Server

    Mai, Sebastian; Plasser, Felix; Marquetand, Philipp; Lischka, Hans; González, Leticia

    2016-01-01

    An efficient perturbational treatment of spin-orbit coupling within the framework of high-level multi-reference techniques has been implemented in the most recent version of the COLUMBUS quantum chemistry package, extending the existing fully variational two-component (2c) multi-reference configuration interaction singles and doubles (MRCISD) method. The proposed scheme follows related implementations of quasi-degenerate perturbation theory (QDPT) model space techniques. Our model space is built either from uncontracted, large-scale scalar relativistic MRCISD wavefunctions or based on the scalar-relativistic solutions of the linear-response-theory-based multi-configurational averaged quadratic coupled cluster method (LRT-MRAQCC). The latter approach allows for a consistent, approximatively size-consistent and size-extensive treatment of spin-orbit coupling. The approach is described in detail and compared to a number of related techniques. The inherent accuracy of the QDPT approach is validated by comparing c...

  12. Application of an electronic bulletin board, as a mechanism of coordination of actions in complex systems - reference model

    Directory of Open Access Journals (Sweden)

    Katarzyna Grzybowska

    2015-06-01

    Full Text Available Background: In her previous research, the author of this publication indicates that coordination is a dependent variable which has a great driving force and is a very unstable factor. This results in the fact that all of the actions connected with coordination have an impact on other factors of cooperation as well as the integration of the enterprises in the structures of a supply chain type structure. Material and methods:  The article has been divided into two basic parts. The first part regards the reference models in complex systems (supply chain systems. They can constitute a starting point for the modelling of target processes in the built supply chain structure. The second part presents template process models (Reference Models for selected action coordination mechanisms during enterprise cooperation. The aim of the article is the presentation the model an Electronic Bulletin Board (EBB, as a mechanism of coordination of actions in complex systems. Results: The article was prepared on the basis of literature from the researched area. The material was also prepared on the basis of interviews with practitioners. They have allowed for the preparation of template process models (Reference Models for selected action coordination methods in the supply chain. Conclusions: The result of the work is a prepared model as well as its description in the use of IDEF0. The presented model is a demonstrative model. The proposed reference model makes it possible to define the parameters of a selected mechanism of coordination of actions, and forms a basis for affecting the progression of the process through an analysis of values of identified parameters. The parameterization of elements constitutes the foundation for the monitoring of the process via 1 unambiguous identification of the object of monitoring and 2 analysis of different variants of the progression of the process.

  13. Application of artificial neural networks for the wind speed prediction of target station using reference stations data

    Energy Technology Data Exchange (ETDEWEB)

    Bilgili, Mehmet; Sahin, Besir; Yasar, Abdulkadir [Cukurova University, Faculty of Engineering and Architecture, Mechanical Engineering Department, 01330 Adana (Turkey)

    2007-11-15

    In this study, artificial neural networks (ANNs) were applied to predict the mean monthly wind speed of any target station using the mean monthly wind speeds of neighboring stations which are indicated as reference stations. Hourly wind speed data, collected by the Turkish State Meteorological Service (TSMS) at 8 measuring stations located in the eastern Mediterranean region of Turkey were used. The long-term wind data, containing hourly wind speeds, directions and related information, cover the period between 1992 and 2001. These data were divided into two sections. According to the correlation coefficients, reference and target stations were defined. The mean monthly wind speeds of reference stations were used and also corresponding months were specified in the input layer of the network. On the other hand, the mean monthly wind speed of the target station was utilized in the output layer of the network. Resilient propagation (RP) learning algorithm was applied in the present simulation. The hidden layers and output layer of the network consist of logistic sigmoid transfer function (logsig) and linear transfer function (purelin) as an activation function. Finally, the values determined by ANN model were compared with the actual data. The maximum mean absolute percentage error was found to be 14.13% for Antakya meteorological station and the best result was found to be 4.49% for Mersin meteorological station. (author)

  14. Development of Chinese reference man deformable surface phantom and its application to the influence of physique on electromagnetic dosimetry.

    Science.gov (United States)

    Yu, D; Wang, M; Liu, Q

    2015-09-07

    A reference man is a theoretical individual that represents the average anatomical structure and physiological and metabolic features of a specific group of people and has been widely used in radiation safety research. With the help of an advantage in deformation, the present work proposed a Chinese reference man adult-male polygon-mesh surface phantom based on the Visible Chinese Human segment image dataset by surface rendering and deforming. To investigate the influence of physique on electromagnetic dosimetry in humans, a series of human phantoms with 10th, 50th and 90th body mass index and body circumference percentile physiques for Chinese adult males were further constructed by deforming the Chinese reference man surface phantom. All the surface phantoms were then voxelized to perform electromagnetic field simulation in a frequency range of 20 MHz to 3 GHz using the finite-difference time-domain method and evaluate the whole-body average and organ average specific absorption rate and the ratios of absorbed energy in skin, fat and muscle to the whole body. The results indicate thinner physique leads to higher WBSAR and the volume of subcutaneous fat, the penetration depth of the electromagnetic field in tissues and standing-wave occurrence may be the influence factors of physique on electromagnetic dosimetry.

  15. Electronics engineer's reference book

    CERN Document Server

    Turner, L W

    1976-01-01

    Electronics Engineer's Reference Book, 4th Edition is a reference book for electronic engineers that reviews the knowledge and techniques in electronics engineering and covers topics ranging from basics to materials and components, devices, circuits, measurements, and applications. This edition is comprised of 27 chapters; the first of which presents general information on electronics engineering, including terminology, mathematical equations, mathematical signs and symbols, and Greek alphabet and symbols. Attention then turns to the history of electronics; electromagnetic and nuclear radiatio

  16. Application of the Böhm chamber for reference beta dose measurements and the calibration of personal dosimeters

    Directory of Open Access Journals (Sweden)

    Skubacz Krystian

    2016-03-01

    Full Text Available Thermoluminescent dosimeters (TLDs currently used in personal and area dosimetry are often utilized to measure doses of ionizing radiation in fields with a more complex structure and therefore they should be calibrated in relation to different radiation types. The results of such calibration presented for UD-813 TLDs allowed for evaluation of their capability in relation to different radiation types like the beta and photon radiation of different energies and neutron radiation generated by the 241Am-Be source. The detector response for 60 keV photons was 10% higher than for the 662 keV gamma radiation of 137Cs. There were also response differences in relation to photon and beta radiation between detectors with an enhanced concentration of lithium 6Li and boron 10B and detectors containing a natural level of these isotopes. Measurements of the reference beta doses were performed with the help of the Böhm chamber. This method is relatively more complicated compared to determining the reference photon and neutron doses and is described thoroughly in this paper. The corrected current measured by the Böhm chamber for the chosen parameters was a linear function for an entire available range of the chamber depths. The percentage of errors related to the evaluated reference beta doses were below 2% despite a rather large number of corrections that should be taken into account. The calibration distances varied from 11 cm to 50 cm. For this range and beta particle energy, the absorption of radiation in the air was negligible and their attenuation had a predominantly geometric character.

  17. Regular Expression Pocket Reference

    CERN Document Server

    Stubblebine, Tony

    2007-01-01

    This handy little book offers programmers a complete overview of the syntax and semantics of regular expressions that are at the heart of every text-processing application. Ideal as a quick reference, Regular Expression Pocket Reference covers the regular expression APIs for Perl 5.8, Ruby (including some upcoming 1.9 features), Java, PHP, .NET and C#, Python, vi, JavaScript, and the PCRE regular expression libraries. This concise and easy-to-use reference puts a very powerful tool for manipulating text and data right at your fingertips. Composed of a mixture of symbols and text, regular exp

  18. Handbook of reference electrodes

    CERN Document Server

    Inzelt, György; Scholz, Fritz

    2013-01-01

    Reference Electrodes are a crucial part of any electrochemical system, yet an up-to-date and comprehensive handbook is long overdue. Here, an experienced team of electrochemists provides an in-depth source of information and data for the proper choice and construction of reference electrodes. This includes all kinds of applications such as aqueous and non-aqueous solutions, ionic liquids, glass melts, solid electrolyte systems, and membrane electrodes. Advanced technologies such as miniaturized, conducting-polymer-based, screen-printed or disposable reference electrodes are also covered. Essen

  19. Reference systems for the determination of {sup 10}B through autoradiography images: Application to a melanoma experimental model

    Energy Technology Data Exchange (ETDEWEB)

    Portu, A., E-mail: portu@cnea.gov.ar [Centro Atomico Constituyentes (CAC), Comision Nacional de Energia Atomica (CNEA), Av. Gral. Paz 1499, AC: B1650KNA, San Martin, Buenos Aires (Argentina)] [Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Rivadavia 1917, AC: C1033AAJ, Ciudad Autonoma de Buenos Aires (Argentina); Carpano, M., E-mail: carpano@cnea.gov.ar [Centro Atomico Constituyentes (CAC), Comision Nacional de Energia Atomica (CNEA), Av. Gral. Paz 1499, AC: B1650KNA, San Martin, Buenos Aires (Argentina); Dagrosa, A., E-mail: dagrosa@cnea.gov.ar [Centro Atomico Constituyentes (CAC), Comision Nacional de Energia Atomica (CNEA), Av. Gral. Paz 1499, AC: B1650KNA, San Martin, Buenos Aires (Argentina)] [Consejo Nacional de Investigaciones Cientificas y Tecnicas (CONICET), Rivadavia 1917, AC: C1033AAJ, Ciudad Autonoma de Buenos Aires (Argentina); Nievas, S., E-mail: nievas@cnea.gov.ar [Centro Atomico Constituyentes (CAC), Comision Nacional de Energia Atomica (CNEA), Av. Gral. Paz 1499, AC: B1650KNA, San Martin, Buenos Aires (Argentina)

    2011-12-15

    The amount of {sup 10}B in tissue samples may be determined by measuring the track density in the autoradiography image produced on a nuclear track detector. Different systems were evaluated as reference standards to be used for a quantitative evaluation of boron concentration. The obtained calibration curves were applied to evaluate the concentration of {sup 10}B in melanoma tumour of NIH nude mice after a biodistribution study. The histological features observed in the tissue sections were accurately reproduced by the autoradiography images.

  20. Perturbational treatment of spin-orbit coupling for generally applicable high-level multi-reference methods

    Energy Technology Data Exchange (ETDEWEB)

    Mai, Sebastian; Marquetand, Philipp; González, Leticia [Institute of Theoretical Chemistry, University of Vienna, Währinger Str. 17, 1090 Vienna (Austria); Müller, Thomas, E-mail: th.mueller@fz-juelich.de [Institute for Advanced Simulation, Jülich Supercomputing Centre, Forschungszentrum Jülich, 52425 Jülich (Germany); Plasser, Felix [Interdisciplinary Center for Scientific Computing, University of Heidelberg, Im Neuenheimer Feld 368, 69120 Heidelberg (Germany); Lischka, Hans [Institute of Theoretical Chemistry, University of Vienna, Währinger Str. 17, 1090 Vienna (Austria); Department of Chemistry and Biochemistry, Texas Tech University, Lubbock, Texas 79409-1061 (United States)

    2014-08-21

    An efficient perturbational treatment of spin-orbit coupling within the framework of high-level multi-reference techniques has been implemented in the most recent version of the COLUMBUS quantum chemistry package, extending the existing fully variational two-component (2c) multi-reference configuration interaction singles and doubles (MRCISD) method. The proposed scheme follows related implementations of quasi-degenerate perturbation theory (QDPT) model space techniques. Our model space is built either from uncontracted, large-scale scalar relativistic MRCISD wavefunctions or based on the scalar-relativistic solutions of the linear-response-theory-based multi-configurational averaged quadratic coupled cluster method (LRT-MRAQCC). The latter approach allows for a consistent, approximatively size-consistent and size-extensive treatment of spin-orbit coupling. The approach is described in detail and compared to a number of related techniques. The inherent accuracy of the QDPT approach is validated by comparing cuts of the potential energy surfaces of acrolein and its S, Se, and Te analoga with the corresponding data obtained from matching fully variational spin-orbit MRCISD calculations. The conceptual availability of approximate analytic gradients with respect to geometrical displacements is an attractive feature of the 2c-QDPT-MRCISD and 2c-QDPT-LRT-MRAQCC methods for structure optimization and ab inito molecular dynamics simulations.

  1. JDBC Pocket Reference

    CERN Document Server

    Bales, Donald

    2003-01-01

    JDBC--the Java Database Connectivity specification--is a complex set of application programming interfaces (APIs) that developers need to understand if they want their Java applications to work with databases. JDBC is so complex that even the most experienced developers need to refresh their memories from time to time on specific methods and details. But, practically speaking, who wants to stop and thumb through a weighty tutorial volume each time a question arises? The answer is the JDBC Pocket Reference, a data-packed quick reference that is both a time-saver and a lifesaver. The JDBC P

  2. Application of a Reference Framework for Integration of Web Resources in Dotlrn--Case Study of Physics--Topic: Waves

    Science.gov (United States)

    Gomez, Fabinton Sotelo; Ordóñez, Armando

    2016-01-01

    Previously a framework for integrating web resources providing educational services in dotLRN was presented. The present paper describes the application of this framework in a rural school in Cauca--Colombia. The case study includes two web resources about the topic of waves (physics) which is oriented in secondary education. Web classes and…

  3. Analysis of laser shock experiments on precompressed samples using a quartz reference and application to warm dense hydrogen and helium

    CERN Document Server

    Brygoo, Stephanie; Loubeyre, Paul; Lazicki, Amy E; Hamel, Sebastien; Qi, Tingting; Celliers, Peter M; Coppari, Federica; Eggert, Jon H; Fratanduono, Dayne E; Hicks, Damien G; Rygg, J Ryan; Smith, Raymond F; Swift, Damian C; Collins, Gilbert W; Jeanloz, Raymond

    2015-01-01

    Megabar (1 Mbar = 100 GPa) laser shocks on precompressed samples allow reaching unprecedented high densities and moderately high 10000-100000K temperatures. We describe here a complete analysis framework for the velocimetry (VISAR) and pyrometry (SOP) data produced in these experiments. Since the precompression increases the initial density of both the sample of interest and the quartz reference for pressure-density, reflectivity and temperature measurements, we describe analytical corrections based on available experimental data on warm dense silica and density-functional-theory based molecular dynamics computer simulations. Using our improved analysis framework we report a re-analysis of previously published data on warm dense hydrogen and helium, compare the newly inferred pressure, density and temperature data with most advanced equation of state models and provide updated reflectivity values.

  4. Development and application of biochemical and haematological reference intervals to identify unhealthy green sea turtles (Chelonia mydas).

    Science.gov (United States)

    Flint, Mark; Morton, John M; Limpus, Colin J; Patterson-Kane, Janet C; Murray, Peter J; Mills, Paul C

    2010-09-01

    Biochemical and haematological reference intervals (RIs) have been reported for sea turtles, but their value for ante-mortem disease diagnosis may be limited due to small sample sizes and outdated statistical analyses. In the present study, 290 green sea turtles (Chelonia mydas) were captured, clinically assessed and blood sampled. Of these, 211 were classified as 'clinically healthy' and 25 as 'clinically unhealthy'. RIs were estimated using data from the healthy turtles and compared with blood values from the unhealthy animals. All of the unhealthy animals had plasma biochemical and haematological values outside one or more RIs (albumin, 48% of unhealthy animals; alkaline phosphatase, 35%; aspartate transaminase, 13%; creatinine, 30%; globulin, 3%; glucose, 34%; lactic dehydrogenase, 26%; phosphorus, 22%; sodium, 13%; thrombocytes, 57%; and monocytes, 5%). Among small immature turtles, those with Chelonibia testudinaria plastron barnacle counts 20 were three times more likely to be unhealthy than those with no barnacles. In addition, small immature and mature turtles were more likely to be unhealthy than large immature turtles.

  5. Measurements of the total-body potassium contents. Application of reference value with the whole-body counter

    Energy Technology Data Exchange (ETDEWEB)

    Yamamoto, Tetsuo [Chiba Univ. (Japan). Inst. for Training Radiological Technicians; Saegusa, Kenji; Arimizu, Noboru; Kuniyasu, Yoshio; Itoh, Hisao

    2001-08-01

    The total-body potassium contents were measured in 405 healthy volunteers and 186 patients with whole body counter in Chiba University Hospital. The total-body potassium contents was expressed by the reference value (R value). The R value was calculated as measured potassium contents (g) divided by the body surface area (m{sup 2}) and adjusted by age and sex of healthy persons. The R value was 100.65{+-}9.22% in 405 healthy volunteers. Those of each disease were as follows: liver cirrhosis; 94.24{+-}11.22%, chronic hepatitis; 95.74{+-}11.24%, hyperthyroidism; 99.37{+-}10.8%, periodic paralysis; 82.0{+-}9.01%, Barter's syndrome; 93.99{+-}9.86%, myasthenia gravis; 97.34{+-}6.42% and hypo-potassemia; 90.64{+-}11.76%, respectively. The R values of other diseases such as uterine cancer, breast cancer, anemia, hypertension were 97.78{+-}11.5%, 99.22{+-}8.88%, 96.64{+-}12.73%, 98.5{+-}9.63% respectively. Fourteen patients showed especially lower R values under 75%. These were 1 liver cirrhosis, 3 hypertension, 1 diabetes mellitus, 3 hypo-potassemia, 1 periodic paralysis, 2 Barter's syndrome, 2 chemical poisoning, and 1 breast cancer. Follow-up study was performed in some patients with the lower R values. The result of follow-up study showed that there was a relationship between improvement of symptoms and increase of total body potassium contents. (author)

  6. Relativistic equation-of-motion coupled-cluster method using open-shell reference wavefunction: Application to ionization potential

    Science.gov (United States)

    Pathak, Himadri; Sasmal, Sudip; Nayak, Malaya K.; Vaval, Nayana; Pal, Sourav

    2016-08-01

    The open-shell reference relativistic equation-of-motion coupled-cluster method within its four-component description is successfully implemented with the consideration of single- and double- excitation approximations using the Dirac-Coulomb Hamiltonian. At the first attempt, the implemented method is employed to calculate ionization potential value of heavy atomic (Ag, Cs, Au, Fr, and Lr) and molecular (HgH and PbF) systems, where the effect of relativity does really matter to obtain highly accurate results. Not only the relativistic effect but also the effect of electron correlation is crucial in these heavy atomic and molecular systems. To justify the fact, we have taken two further approximations in the four-component relativistic equation-of-motion framework to quantify how the effect of electron correlation plays a role in the calculated values at different levels of theory. All these calculated results are compared with the available experimental data as well as with other theoretically calculated values to judge the extent of accuracy obtained in our calculations.

  7. Python library reference

    NARCIS (Netherlands)

    Rossum, G. van

    1995-01-01

    Python is an extensible, interpreted, object-oriented programming language. It supports a wide range of applications, from simple text processing scripts to interactive WWW browsers. While the Python Reference Manual describes the exact syntax and semantics of the language, it does not describe the

  8. Synthetic growth reference charts

    NARCIS (Netherlands)

    Hermanussen, Michael; Stec, Karol; Aßmann, Christian; Meigen, Christof; Van Buuren, Stef

    2016-01-01

    Objectives: To reanalyze the between-population variance in height, weight, and body mass index (BMI), and to provide a globally applicable technique for generating synthetic growth reference charts. Methods: Using a baseline set of 196 female and 197 male growth studies published since 1831, common

  9. Surface and bulk characterization of an ultrafine South African coal fly ash with reference to polymer applications

    Science.gov (United States)

    van der Merwe, E. M.; Prinsloo, L. C.; Mathebula, C. L.; Swart, H. C.; Coetsee, E.; Doucet, F. J.

    2014-10-01

    South African coal-fired power stations produce about 25 million tons of fly ash per annum, of which only approximately 5% is currently reused. A growing concern about pollution and increasing landfill costs stimulates research into new ways to utilize coal fly ash for economically beneficial applications. Fly ash particles may be used as inorganic filler in polymers, an application which generally requires the modification of their surface properties. In order to design experiments that will result in controlled changes in surface chemistry and morphology, a detailed knowledge of the bulk chemical and mineralogical compositions of untreated fly ash particles, as well as their morphology and surface properties, is needed. In this paper, a combination of complementary bulk and surface techniques was explored to assess the physicochemical properties of a classified, ultrafine coal fly ash sample, and the findings were discussed in the context of polymer application as fillers. The sample was categorized as a Class F fly ash (XRF). Sixty-two percent of the sample was an amorphous glass phase, with mullite and quartz being the main identified crystalline phases (XRD, FTIR). Quantitative carbon and sulfur analysis reported a total bulk carbon and sulfur content of 0.37% and 0.16% respectively. The spatial distribution of the phases was determined by 2D mapping of Raman spectra, while TGA showed a very low weight loss for temperatures ranging between 25 and 1000 °C. Individual fly ash particles were characterized by a monomodal size distribution (PSD) of spherical particles with smooth surfaces (SEM, TEM, AFM), and a mean particle size of 4.6 μm (PSD). The BET active surface area of this sample was 1.52 m2/g and the chemical composition of the fly ash surface (AES, XPS) was significantly different from the bulk composition and varied considerably between spheres. Many properties of the sample (e.g. spherical morphology, small particle size, thermal stability) appeared

  10. Simultaneous determination of Si, Al and Na concentrations by particle induced gamma-ray emission and applications to reference materials and ceramic archaeological artifacts

    Energy Technology Data Exchange (ETDEWEB)

    Dasari, K.B. [Radiochemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India); GITAM Institute of Science, GITAM University, Visakhapatnam 530045 (India); Chhillar, S. [Radiochemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India); Acharya, R., E-mail: racharya@barc.gov.in [Radiochemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India); Ray, D.K.; Behera, A. [Ion Beam Laboratory, Institute of Physics, Bhubaneswar 751005 (India); Lakshmana Das, N. [GITAM Institute of Science, GITAM University, Visakhapatnam 530045 (India); Pujari, P.K. [Radiochemistry Division, Bhabha Atomic Research Centre, Trombay, Mumbai 400085 (India)

    2014-11-15

    A particle induced gamma ray emission (PIGE) method using 4 MeV proton beam was standardized for simultaneous determination of Si, Al and Na concentrations and has been applied for non-destructive analysis of several reference materials and archaeological clay pottery samples. Current normalized count rates of gamma-rays for the three elements listed above were obtained by an in situ method using Li as internal standard. The paper presents application of the in situ current normalized PIGE method for grouping study of 39 clay potteries, obtained from Rajasthan and Andhra Pradesh states of India. Grouping of artifacts was carried out using the ratios of SiO{sub 2} to Al{sub 2}O{sub 3} concentrations, due to their non volatile nature. Powder samples and elemental standards in pellet forms (cellulose matrix) were irradiated using the 4 MeV proton beam (∼10 nA) from the 3 MV tandem accelerator at IOP Bhubaneswar, and assay of prompt gamma rays was carried out using a 60% relative efficiency HPGe detector coupled to MCA. The concentration ratio values of SiO{sub 2}/Al{sub 2}O{sub 3} indicated that pottery samples fell into two major groups, which are in good agreement with their collection areas. Reference materials from IAEA and NIST were analyzed for quantification of Si, Al and Na concentrations as a part of validation as well as application of PIGE method.

  11. Simultaneous determination of Si, Al and Na concentrations by particle induced gamma-ray emission and applications to reference materials and ceramic archaeological artifacts

    Science.gov (United States)

    Dasari, K. B.; Chhillar, S.; Acharya, R.; Ray, D. K.; Behera, A.; Lakshmana Das, N.; Pujari, P. K.

    2014-11-01

    A particle induced gamma ray emission (PIGE) method using 4 MeV proton beam was standardized for simultaneous determination of Si, Al and Na concentrations and has been applied for non-destructive analysis of several reference materials and archaeological clay pottery samples. Current normalized count rates of gamma-rays for the three elements listed above were obtained by an in situ method using Li as internal standard. The paper presents application of the in situ current normalized PIGE method for grouping study of 39 clay potteries, obtained from Rajasthan and Andhra Pradesh states of India. Grouping of artifacts was carried out using the ratios of SiO2 to Al2O3 concentrations, due to their non volatile nature. Powder samples and elemental standards in pellet forms (cellulose matrix) were irradiated using the 4 MeV proton beam (∼10 nA) from the 3 MV tandem accelerator at IOP Bhubaneswar, and assay of prompt gamma rays was carried out using a 60% relative efficiency HPGe detector coupled to MCA. The concentration ratio values of SiO2/Al2O3 indicated that pottery samples fell into two major groups, which are in good agreement with their collection areas. Reference materials from IAEA and NIST were analyzed for quantification of Si, Al and Na concentrations as a part of validation as well as application of PIGE method.

  12. Electrical engineer's reference book

    CERN Document Server

    Jones, G R

    2013-01-01

    A long established reference book: radical revision for the fifteenth edition includes complete rearrangement to take in chapters on new topics and regroup the subjects covered for easy access to information.The Electrical Engineer's Reference Book, first published in 1945, maintains its original aims: to reflect the state of the art in electrical science and technology and cater for the needs of practising engineers. Most chapters have been revised and many augmented so as to deal properly with both fundamental developments and new technology and applications that have come to the fore since

  13. Application of distance-coded reference measuring system on rotary swivel drive of the 3D laser cutting machine%距离编码测量装置在三维激光切割机上的应用

    Institute of Scientific and Technical Information of China (English)

    翟东升; 钟昇; 洪超

    2013-01-01

    The application method of distance-coded reference measuring system on rotary swivel drive of the 3D laser cutting machine has been introduced in the text. The above method and conclusion provide reference for the application of distance-coded reference measuring system on other machine tools.%本文主要介绍带距离编码参考点标记的测量装置在三维激光切割机旋转机构上的应用方法,可为距离编码测量装置的应用提供参考.

  14. Application of genotyping-by-sequencing on semiconductor sequencing platforms: a comparison of genetic and reference-based marker ordering in barley.

    Directory of Open Access Journals (Sweden)

    Martin Mascher

    Full Text Available The rapid development of next-generation sequencing platforms has enabled the use of sequencing for routine genotyping across a range of genetics studies and breeding applications. Genotyping-by-sequencing (GBS, a low-cost, reduced representation sequencing method, is becoming a common approach for whole-genome marker profiling in many species. With quickly developing sequencing technologies, adapting current GBS methodologies to new platforms will leverage these advancements for future studies. To test new semiconductor sequencing platforms for GBS, we genotyped a barley recombinant inbred line (RIL population. Based on a previous GBS approach, we designed bar code and adapter sets for the Ion Torrent platforms. Four sets of 24-plex libraries were constructed consisting of 94 RILs and the two parents and sequenced on two Ion platforms. In parallel, a 96-plex library of the same RILs was sequenced on the Illumina HiSeq 2000. We applied two different computational pipelines to analyze sequencing data; the reference-independent TASSEL pipeline and a reference-based pipeline using SAMtools. Sequence contigs positioned on the integrated physical and genetic map were used for read mapping and variant calling. We found high agreement in genotype calls between the different platforms and high concordance between genetic and reference-based marker order. There was, however, paucity in the number of SNP that were jointly discovered by the different pipelines indicating a strong effect of alignment and filtering parameters on SNP discovery. We show the utility of the current barley genome assembly as a framework for developing very low-cost genetic maps, facilitating high resolution genetic mapping and negating the need for developing de novo genetic maps for future studies in barley. Through demonstration of GBS on semiconductor sequencing platforms, we conclude that the GBS approach is amenable to a range of platforms and can easily be modified as new

  15. Application of genotyping-by-sequencing on semiconductor sequencing platforms: a comparison of genetic and reference-based marker ordering in barley.

    Science.gov (United States)

    Mascher, Martin; Wu, Shuangye; Amand, Paul St; Stein, Nils; Poland, Jesse

    2013-01-01

    The rapid development of next-generation sequencing platforms has enabled the use of sequencing for routine genotyping across a range of genetics studies and breeding applications. Genotyping-by-sequencing (GBS), a low-cost, reduced representation sequencing method, is becoming a common approach for whole-genome marker profiling in many species. With quickly developing sequencing technologies, adapting current GBS methodologies to new platforms will leverage these advancements for future studies. To test new semiconductor sequencing platforms for GBS, we genotyped a barley recombinant inbred line (RIL) population. Based on a previous GBS approach, we designed bar code and adapter sets for the Ion Torrent platforms. Four sets of 24-plex libraries were constructed consisting of 94 RILs and the two parents and sequenced on two Ion platforms. In parallel, a 96-plex library of the same RILs was sequenced on the Illumina HiSeq 2000. We applied two different computational pipelines to analyze sequencing data; the reference-independent TASSEL pipeline and a reference-based pipeline using SAMtools. Sequence contigs positioned on the integrated physical and genetic map were used for read mapping and variant calling. We found high agreement in genotype calls between the different platforms and high concordance between genetic and reference-based marker order. There was, however, paucity in the number of SNP that were jointly discovered by the different pipelines indicating a strong effect of alignment and filtering parameters on SNP discovery. We show the utility of the current barley genome assembly as a framework for developing very low-cost genetic maps, facilitating high resolution genetic mapping and negating the need for developing de novo genetic maps for future studies in barley. Through demonstration of GBS on semiconductor sequencing platforms, we conclude that the GBS approach is amenable to a range of platforms and can easily be modified as new sequencing

  16. Development and field application of a nonlinear ultrasonic modulation technique for fatigue crack detection without reference data from an intact condition

    Science.gov (United States)

    Lim, Hyung Jin; Kim, Yongtak; Koo, Gunhee; Yang, Suyoung; Sohn, Hoon; Bae, In-hwan; Jang, Jeong-Hwan

    2016-09-01

    In this study, a fatigue crack detection technique, which detects a fatigue crack without relying on any reference data obtained from the intact condition of a target structure, is developed using nonlinear ultrasonic modulation and applied to a real bridge structure. Using two wafer-type lead zirconate titanate (PZT) transducers, ultrasonic excitations at two distinctive frequencies are applied to a target inspection spot and the corresponding ultrasonic response is measured by another PZT transducer. Then, the nonlinear modulation components produced by a breathing-crack are extracted from the measured ultrasonic response, and a statistical classifier, which can determine if the nonlinear modulation components are statistically significant in comparison with the background noise level, is proposed. The effectiveness of the proposed fatigue crack detection technique is experimentally validated using the data obtained from aluminum plates and aircraft fitting-lug specimens under varying temperature and loading conditions, and through a field testing of Yeongjong Grand Bridge in South Korea. The uniqueness of this study lies in that (1) detection of a micro fatigue crack with less than 1 μm width and fatigue cracks in the range of 10-20 μm in width using nonlinear ultrasonic modulation, (2) automated detection of fatigue crack formation without using reference data obtained from an intact condition, (3) reliable and robust diagnosis under varying temperature and loading conditions, (4) application of a local fatigue crack detection technique to online monitoring of a real bridge.

  17. Application of the informational reference system OZhUR to the automated processing of data from satellites of the Kosmos series

    Science.gov (United States)

    Pokras, V. M.; Yevdokimov, V. P.; Maslov, V. D.

    1978-01-01

    The structure and potential of the information reference system OZhUR designed for the automated data processing systems of scientific space vehicles (SV) is considered. The system OZhUR ensures control of the extraction phase of processing with respect to a concrete SV and the exchange of data between phases.The practical application of the system OZhUR is exemplified in the construction of a data processing system for satellites of the Cosmos series. As a result of automating the operations of exchange and control, the volume of manual preparation of data is significantly reduced, and there is no longer any need for individual logs which fix the status of data processing. The system Ozhur is included in the automated data processing system Nauka which is realized in language PL-1 in a binary one-address system one-state (BOS OS) electronic computer.

  18. Enterprise Reference Library

    Science.gov (United States)

    Bickham, Grandin; Saile, Lynn; Havelka, Jacque; Fitts, Mary

    2011-01-01

    Introduction: Johnson Space Center (JSC) offers two extensive libraries that contain journals, research literature and electronic resources. Searching capabilities are available to those individuals residing onsite or through a librarian s search. Many individuals have rich collections of references, but no mechanisms to share reference libraries across researchers, projects, or directorates exist. Likewise, information regarding which references are provided to which individuals is not available, resulting in duplicate requests, redundant labor costs and associated copying fees. In addition, this tends to limit collaboration between colleagues and promotes the establishment of individual, unshared silos of information The Integrated Medical Model (IMM) team has utilized a centralized reference management tool during the development, test, and operational phases of this project. The Enterprise Reference Library project expands the capabilities developed for IMM to address the above issues and enhance collaboration across JSC. Method: After significant market analysis for a multi-user reference management tool, no available commercial tool was found to meet this need, so a software program was built around a commercial tool, Reference Manager 12 by The Thomson Corporation. A use case approach guided the requirements development phase. The premise of the design is that individuals use their own reference management software and export to SharePoint when their library is incorporated into the Enterprise Reference Library. This results in a searchable user-specific library application. An accompanying share folder will warehouse the electronic full-text articles, which allows the global user community to access full -text articles. Discussion: An enterprise reference library solution can provide a multidisciplinary collection of full text articles. This approach improves efficiency in obtaining and storing reference material while greatly reducing labor, purchasing and

  19. Instrumentation reference book

    CERN Document Server

    Boyes, Walt

    2002-01-01

    Instrumentation is not a clearly defined subject, having a 'fuzzy' boundary with a number of other disciplines. Often categorized as either 'techniques' or 'applications' this book addresses the various applications that may be needed with reference to the practical techniques that are available for the instrumentation or measurement of a specific physical quantity or quality. This makes it of direct interest to anyone working in the process, control and instrumentation fields where these measurements are essential.* Comprehensive and authoritative collection of technical information* Writte

  20. VBScript pocket reference

    CERN Document Server

    Lomax, Paul; Petrusha, Ron

    2008-01-01

    Microsoft's Visual Basic Scripting Edition (VBScript), a subset of Visual Basic for Applications, is a powerful language for Internet application development, where it can serve as a scripting language for server-side, client-side, and system scripting. Whether you're developing code for Active Server Pages, client-side scripts for Internet Explorer, code for Outlook forms, or scripts for Windows Script Host, VBScript Pocket Reference will be your constant companion. Don't let the pocket-friendly format fool you. Based on the bestsellingVBScript in a Nutshell, this small book details every V

  1. The Construction and Application of Personal References Library Based on Reference Manager Software%基于RM的个人参考文献图书馆的构建与应用

    Institute of Scientific and Technical Information of China (English)

    牛玲

    2006-01-01

    个人参考文献的集中化管理是科研工作者必须要面临的难题.本文首先比较了目前流行的信息管理软件Reference Manager、Endnote和Pro-Cite,接着以Reference Manager为例,论述了构建个人参考文献图书馆的多种方法:人工录入,联机检索导入和网络检索间接导入;并详细说明了个人议.参考文献的使用方法,最后对Reference Manager的不足提出自己的建议.

  2. 蒸散发模拟的Valiantzas方法在中国的应用%Application of Valiantzas approach to estimating reference evapotranspiration in China

    Institute of Scientific and Technical Information of China (English)

    潘云; 宫辉力; 李小娟; 朱琳; 张静

    2011-01-01

    accurate reference evapotranspiration than that obtained by other two widely used models (Priestley-Taylor and Hargreaves). The Penman-Valiantzas model is further tested using the long-term measurement observed at the Yanqing Station in Beijing. The result of a 20-year monthly simulation reveals that the correlation coefficients between reference evapotranspirations calculated by the Penman-Valiantzas model and the FAO Penman-Menteith model as well as observed by the pan observation at the station are 97.84% and 86.38% , respectively. The daily simulation of reference evapotranspiration using the Penman-Valiantzas-Hargreaves model has also been improved.Our results demonstrate the applicability of the two new models in China in the absence of the wind speed and sunshine hour data date.

  3. Library Reference Services.

    Science.gov (United States)

    Miller, Constance; And Others

    1985-01-01

    Seven articles on library reference services highlight reference obsolescence in academic libraries, major studies of unobtrusive reference tests, methods for evaluating reference desk performance, reference interview evaluation, problems of reference desk control, online searching by end users, and reference collection development in…

  4. Development of molecular closures for the reference interaction site model theory with application to square-well and Lennard-Jones homonuclear diatomics

    Science.gov (United States)

    Munaò, Gianmarco; Costa, Dino; Caccamo, Carlo

    2016-10-01

    Inspired by significant improvements obtained for the performances of the polymer reference interaction site model (PRISM) theory of the fluid phase when coupled with ‘molecular closures’ (Schweizer and Yethiraj 1993 J. Chem. Phys. 98 9053), we exploit a matrix generalization of this concept, suitable for the more general RISM framework. We report a preliminary test of the formalism, as applied to prototype square-well homonuclear diatomics. As for the structure, comparison with Monte Carlo shows that molecular closures are slightly more predictive than their ‘atomic’ counterparts, and thermodynamic properties are equally accurate. We also devise an application of molecular closures to models interacting via continuous, soft-core potentials, by using well established prescriptions in liquid state perturbation theories. In the case of Lennard-Jones dimers, our scheme definitely improves over the atomic one, providing semi-quantitative structural results, and quite good estimates of internal energy, pressure and phase coexistence. Our finding paves the way to a systematic employment of molecular closures within the RISM framework to be applied to more complex systems, such as molecules constituted by several non-equivalent interaction sites.

  5. Proposal of simple and novel method of capacity fading analysis using pseudo-reference electrode in lithium ion cells: Application to solvent-free lithium ion polymer batteries

    Science.gov (United States)

    Shono, Kumi; Kobayashi, Takeshi; Tabuchi, Masato; Ohno, Yasutaka; Miyashiro, Hajime; Kobayashi, Yo

    2014-02-01

    We propose a simple procedure for introducing a pseudo-reference electrode (PRE) to lithium ion batteries using isometric lithium metal placed between the cathode and anode, and we successfully obtained the cathode and anode voltage profiles, individual interfacial impedances, and the misalignment of the operation range between the cathode and anode after cycle operation. The proposed procedure is applicable to lithium ion battery systems using a solid electrolyte to prepare two cells with a lithium counter electrode. We determined the capacity decrease of a solvent-free lithium ion polymer battery consisting of a LiNi1/3Mn1/3Co1/3O2 (NMC), a polyether-based solid polymer electrolyte (SPE), and a graphite (Gr) with the proposed PRE over 1000 cycles. The capacity retention of the [Gr|SPE|NMC] cell reached 50% at the 1000th cycle upon the optimization of cell preparation, and we found that the main factor of the capacity decrease was the continuous irreversible loss of active lithium at the graphite anode, not the oxidation of the SPE. Our findings suggest that we should reconsider combining a polyether-based SPE with a conventionally used 4 V class cathode and a graphite anode to develop an innovative, safe, and low-cost battery for the expected large lithium ion battery systems for stationary use.

  6. Electronics engineer's reference book

    CERN Document Server

    Mazda, F F

    1989-01-01

    Electronics Engineer's Reference Book, Sixth Edition is a five-part book that begins with a synopsis of mathematical and electrical techniques used in the analysis of electronic systems. Part II covers physical phenomena, such as electricity, light, and radiation, often met with in electronic systems. Part III contains chapters on basic electronic components and materials, the building blocks of any electronic design. Part IV highlights electronic circuit design and instrumentation. The last part shows the application areas of electronics such as radar and computers.

  7. Xcode 5 developer reference

    CERN Document Server

    Wentk, Richard

    2014-01-01

    Design, code, and build amazing apps with Xcode 5 Thanks to Apple's awesome Xcode development environment, you can create the next big app for Macs, iPhones, iPads, or iPod touches. Xcode 5 contains gigabytes of great stuff to help you develop for both OS X and iOS devices - things like sample code, utilities, companion applications, documentation, and more. And with Xcode 5 Developer Reference, you now have the ultimate step-by-step guide to it all. Immerse yourself in the heady and lucrative world of Apple app development, see how to tame the latest features and functions, and find loads of

  8. Selecting the optimal method to calculate daily global reference potential evaporation from CFSR reanalysis data for application in a hydrological model study

    Directory of Open Access Journals (Sweden)

    F. C. Sperna Weiland

    2012-03-01

    Full Text Available Potential evaporation (PET is one of the main inputs of hydrological models. Yet, there is limited consensus on which PET equation is most applicable in hydrological climate impact assessments. In this study six different methods to derive global scale reference PET daily time series from Climate Forecast System Reanalysis (CFSR data are compared: Penman-Monteith, Priestley-Taylor and original and re-calibrated versions of the Hargreaves and Blaney-Criddle method. The calculated PET time series are (1 evaluated against global monthly Penman-Monteith PET time series calculated from CRU data and (2 tested on their usability for modeling of global discharge cycles.

    A major finding is that for part of the investigated basins the selection of a PET method may have only a minor influence on the resulting river flow. Within the hydrological model used in this study the bias related to the PET method tends to decrease while going from PET, AET and runoff to discharge calculations. However, the performance of individual PET methods appears to be spatially variable, which stresses the necessity to select the most accurate and spatially stable PET method. The lowest root mean squared differences and the least significant deviations (95% significance level between monthly CFSR derived PET time series and CRU derived PET were obtained for a cell-specific re-calibrated Blaney-Criddle equation. However, results show that this re-calibrated form is likely to be unstable under changing climate conditions and less reliable for the calculation of daily time series. Although often recommended, the Penman-Monteith equation applied to the CFSR data did not outperform the other methods in a evaluation against PET derived with the Penman-Monteith equation from CRU data. In arid regions (e.g. Sahara, central Australia, US deserts, the equation resulted in relatively low PET values and, consequently, led to relatively high discharge values for dry basins (e

  9. Virtual reference services

    OpenAIRE

    Márdero Arellano, Miguel Ángel

    2001-01-01

    Analysis of virtual reference services, their standandars and new technologies that have changed the tradicional practice at the library’s reference desk. Major American virtual reference services initiatives and their characteristics are described.

  10. Establishment of a reference interval for natural killer cell activity through flow cytometry and its clinical application in the diagnosis of hemophagocytic lymphohistiocytosis.

    Science.gov (United States)

    Chung, H J; Park, C J; Lim, J H; Jang, S; Chi, H S; Im, H J; Seo, J J

    2010-04-01

    Recently, the Histiocyte Society revised the diagnostic criteria for hemophagocytic lymphohistiocytosis (HLH) to include low or absent natural killer (NK) cell activity, according to local laboratory reference. The aim of this study was to establish reference interval for functional NK-cell activity in 63 healthy Korean individuals using a flow-cytometric assay. We used peripheral blood mononuclear cells (PBMCs) as effector cells and Fluorescein isothiocyanate-labeled K562 cells as target cells. NK-cell activity was calculated using the following equation: NK-cell activity (%) = (test lysis - spontaneous lysis) x 100/(maximum lysis - spontaneous lysis). NK-cell activity was analyzed in 13 known HLH patients and 16 suspected non-HLH patients using a flow-cytometric assay. The mean (+/-SD) cytotoxicity of PBMCs from healthy individuals was 20.9 +/- 5.3% and the reference interval was 11.8-31.9%. The mean NK-cell activity of HLH patients (8.3 +/- 8.9%) was significantly lower (P = 0.001) than that of non-HLH patients (20.1 +/- 7.8%). The sequential changes in NK-cell activity in the HLH group corresponded to clinical and laboratory findings following treatment. We successfully developed a functional NK-cell activity test for use in the clinical laboratory and obtained a reference interval of NK-cell activity from healthy donors. This assay, and associated reference interval, was used to analyze 30 clinically relevant specimens and the results were shown to be well correlated.

  11. Magnetohydrodynamic inertial reference system

    Science.gov (United States)

    Eckelkamp-Baker, Dan; Sebesta, Henry R.; Burkhard, Kevin

    2000-07-01

    Optical platforms increasingly require attitude knowledge and optical instrument pointing at sub-microradian accuracy. No low-cost commercial system exists to provide this level of accuracy for guidance, navigation, and control. The need for small, inexpensive inertial sensors, which may be employed in pointing control systems that are required to satisfy angular line-of-sight stabilization jitter error budgets to levels of 1-3 microradian rms and less, has existed for at least two decades. Innovations and evolutions in small, low-noise inertial angular motion sensor technology and advances in the applications of the global positioning system have converged to allow improvement in acquisition, tracking and pointing solutions for a wide variety of payloads. We are developing a small, inexpensive, and high-performance inertial attitude reference system that uses our innovative magnetohydrodynamic angular rate sensor technology.

  12. Rational Application and Reflection of References in Thesis Writing%参考文献在论文写作中的合理应用及思考

    Institute of Scientific and Technical Information of China (English)

    陆遐

    2014-01-01

    The quotations should be identified correctly by standard, scientific and reasonable method in the use of the references. This paper analyzes how to use references rationally in thesis writing, elaborates the meaning and inspection methods of the references, and provides help for thesis writing.%在参考文献的使用上,需以规范、科学、合理的方式,正确地进行引文标识。本文就在论文的写作中如何合理运用参考文献的问题进行分析,对参考文献的意义、查阅方法等问题进行阐述,为论文的写作提供一定帮助。

  13. Reference Models for Virtual Enterprises

    DEFF Research Database (Denmark)

    Tølle, Martin; Bernus, Peter; Vesterager, Johan

    2002-01-01

    This paper analyses different types of Reference Models (RMs) applicable to support the set up and (re)configuration of virtual enterprises (VEs). RMs are models capturing concepts common to VEs aiming to convert the task of setting up of VE towards a configuration task, and hence reduce the time...... needed for VE creation. The RMs are analysed through a mapping onto the Virtual Enterprise Reference Architecture (VERA) created in the IMS GLOBEMEN project based upon GERAM.......This paper analyses different types of Reference Models (RMs) applicable to support the set up and (re)configuration of virtual enterprises (VEs). RMs are models capturing concepts common to VEs aiming to convert the task of setting up of VE towards a configuration task, and hence reduce the time...

  14. Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): reference data for the trunk and application in patients with chronic postherpetic neuralgia.

    Science.gov (United States)

    Pfau, Doreen B; Krumova, Elena K; Treede, Rolf-Detlef; Baron, Ralf; Toelle, Thomas; Birklein, Frank; Eich, Wolfgang; Geber, Christian; Gerhardt, Andreas; Weiss, Thomas; Magerl, Walter; Maier, Christoph

    2014-05-01

    Age- and gender-matched reference values are essential for the clinical use of quantitative sensory testing (QST). To extend the standard test sites for QST-according to the German Research Network on Neuropathic Pain-to the trunk, we collected QST profiles on the back in 162 healthy subjects. Sensory profiles for standard test sites were within normal interlaboratory differences. QST revealed lower sensitivity on the upper back than the hand, and higher sensitivity on the lower back than the foot, but no systematic differences between these trunk sites. Age effects were significant for most parameters. Females exhibited lower pressure pain thresholds (PPT) than males, which was the only significant gender difference. Values outside the 95% confidence interval of healthy subjects (considered abnormal) required temperature changes of >3.3-8.2 °C for thermal detection. For cold pain thresholds, confidence intervals extended mostly beyond safety cutoffs, hence only relative reference data (left-right differences, hand-trunk differences) were sufficiently sensitive. For mechanical detection and pain thresholds, left-right differences were 1.5-2.3 times more sensitive than absolute reference data. The most sensitive parameter was PPT, where already side-to-side differences >35% were abnormal. Compared to trunk reference data, patients with postherpetic neuralgia exhibited thermal and tactile deficits and dynamic mechanical allodynia, mostly without reduced mechanical pain thresholds. This pattern deviates from other types of neuropathic pain. QST reference data for the trunk will also be useful for patients with postthoracotomy pain or chronic back pain.

  15. 2002 reference document; Document de reference 2002

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    This 2002 reference document of the group Areva, provides information on the society. Organized in seven chapters, it presents the persons responsible for the reference document and for auditing the financial statements, information pertaining to the transaction, general information on the company and share capital, information on company operation, changes and future prospects, assets, financial position, financial performance, information on company management and executive board and supervisory board, recent developments and future prospects. (A.L.B.)

  16. Application of Isotope Dilution Mass Spectrometry for Reference Measurements of Cadmium. Copper, Mercury, Lead, Zinc and Methyl Mercury in Marine Sediment Sample

    Directory of Open Access Journals (Sweden)

    Vasileva E.

    2013-04-01

    Full Text Available Marine sediment was selected as a test sample for the laboratory inter-comparison studies organized by the Environment Laboratoryes of the International Atomic Energy. The analytical procedure to establish the reference values for the Cd, Cu, Hg, Methyl Hg, Pb and Zn amount contents was based on Isotope Dilution Inductively Coupled Plasma-Mass Spectrometry (ID ICP-MS applied as a primary method of measurement..The Hg and Methyl Hg determination will be detailed more specifically because of the problems encountered with this element, including sample homogeneity issues, memory effects and possible matrix effects during the ICP- MS measurement stage. Reference values, traceable to the SI, with total uncertainties of less than 2% relative expanded uncertainty (k=2 were obtained for Cd, Cu, Zn and Pb and around 5% for Hg and CH3Hg.

  17. Development of a 690 K SNP array in catfish and its application for genetic mapping and validation of the reference genome sequence

    Science.gov (United States)

    Zeng, Qifan; Fu, Qiang; Li, Yun; Waldbieser, Geoff; Bosworth, Brian; Liu, Shikai; Yang, Yujia; Bao, Lisui; Yuan, Zihao; Li, Ning; Liu, Zhanjiang

    2017-01-01

    Single nucleotide polymorphisms (SNPs) are capable of providing the highest level of genome coverage for genomic and genetic analysis because of their abundance and relatively even distribution in the genome. Such a capacity, however, cannot be achieved without an efficient genotyping platform such as SNP arrays. In this work, we developed a high-density SNP array with 690,662 unique SNPs (herein 690 K array) that were relatively evenly distributed across the entire genome, and covered 98.6% of the reference genome sequence. Here we also report linkage mapping using the 690 K array, which allowed mapping of over 250,000 SNPs on the linkage map, the highest marker density among all the constructed linkage maps. These markers were mapped to 29 linkage groups (LGs) with 30,591 unique marker positions. This linkage map anchored 1,602 scaffolds of the reference genome sequence to LGs, accounting for over 97% of the total genome assembly. A total of 1,007 previously unmapped scaffolds were placed to LGs, allowing validation and in few instances correction of the reference genome sequence assembly. This linkage map should serve as a valuable resource for various genetic and genomic analyses, especially for GWAS and QTL mapping for genes associated with economically important traits. PMID:28079141

  18. Development of real-time PCR method for the detection and the quantification of a new endogenous reference gene in sugar beet "Beta vulgaris L.": GMO application.

    Science.gov (United States)

    Chaouachi, Maher; Alaya, Akram; Ali, Imen Ben Haj; Hafsa, Ahmed Ben; Nabi, Nesrine; Bérard, Aurélie; Romaniuk, Marcel; Skhiri, Fethia; Saïd, Khaled

    2013-01-01

    KEY MESSAGE : Here, we describe a new developed quantitative real-time PCR method for the detection and quantification of a new specific endogenous reference gene used in GMO analysis. The key requirement of this study was the identification of a new reference gene used for the differentiation of the four genomic sections of the sugar beet (Beta vulgaris L.) (Beta, Corrollinae, Nanae and Procumbentes) suitable for quantification of genetically modified sugar beet. A specific qualitative polymerase chain reaction (PCR) assay was designed to detect the sugar beet amplifying a region of the adenylate transporter (ant) gene only from the species of the genomic section I of the genus Beta (cultivated and wild relatives) and showing negative PCR results for 7 species of the 3 other sections, 8 related species and 20 non-sugar beet plants. The sensitivity of the assay was 15 haploid genome copies (HGC). A quantitative real-time polymerase chain reaction (QRT-PCR) assay was also performed, having high linearity (R (2) > 0.994) over sugar beet standard concentrations ranging from 20,000 to 10 HGC of the sugar beet DNA per PCR. The QRT-PCR assay described in this study was specific and more sensitive for sugar beet quantification compared to the validated test previously reported in the European Reference Laboratory. This assay is suitable for GMO quantification in routine analysis from a wide variety of matrices.

  19. Development of an orange juice in-house reference material and its application to guarantee the quality of vitamin C determination in fruits, juices and fruit pulps.

    Science.gov (United States)

    Valente, A; Sanches-Silva, A; Albuquerque, T G; Costa, H S

    2014-07-01

    Reference materials are useful for the quality control of analytical procedures and to evaluate the performance of laboratories. There are few and expensive certified reference materials commercially available for vitamin C or ascorbic acid analysis in food matrices. In this study, the preparation and the suitability assessment of an orange juice in-house reference material (RM) for vitamin C analysis in fruits, juices and in fruit pulps is described. This RM was used for the development and full validation of an HPLC method. The results showed excellent linearity (r(2)=0.9995), good accuracy (96.6-97.3%) and precision, as relative standard deviation, ranged from 0.70% to 3.67%. The in-house RM was homogenous and stable at storage conditions (-80°C) during 12 months. According to our results, this in-house RM is an excellent tool to use in quality control and method verification purposes for vitamin C analysis of fruits, juices and fruit pulps matrices. Furthermore, a stabilization solution with perchloric and metaphosphoric acids was developed which prevents degradation of ascorbic acid for a period of 12 months at -80°C.

  20. Electrical engineering a pocket reference

    CERN Document Server

    Schmidt-Walter, Heinz

    2007-01-01

    This essential reference offers you a well-organized resource for accessing the basic electrical engineering knowledge you need for your work. Whether you're an experienced engineer who appreciates an occasional refresher in key areas, or a student preparing to enter the field, Electrical Engineering: A Pocket Reference provides quick and easy access to fundamental principles and their applications. You also find an extensive collection of time-saving equations that help simplify your daily projects.Supported with more than 500 diagrams and figures, 60 tables, and an extensive index, this uniq

  1. Genetics Home Reference

    Science.gov (United States)

    Skip Navigation Bar Home Current Issue Past Issues Genetics Home Reference Past Issues / Spring 2007 Table of ... of this page please turn Javascript on. The Genetics Home Reference (GHR) Web site — ghr.nlm.nih. ...

  2. CMS Statistics Reference Booklet

    Data.gov (United States)

    U.S. Department of Health & Human Services — The annual CMS Statistics reference booklet provides a quick reference for summary information about health expenditures and the Medicare and Medicaid health...

  3. Best Reference Sources 2001.

    Science.gov (United States)

    Coutts, Brian; McConnell, Tamara

    2002-01-01

    Presents an annotated list of the best reference materials published in 2001. Discusses activity in the reference publishing industry; costs; and lists print materials, Web sites, databases, and CD-ROMs. (LRW)

  4. Transfer factor (diffusing capacity) standardized for alveolar volume: validation, reference values and applications of a new linear model to replace KCO (TL/VA)

    Science.gov (United States)

    Chinn, D J; Cotes, J E; Flowers, R; Marks, A M; Reed, J W

    1996-06-01

    Transfer factor (TL) varies with alveolar volume (VA), but not in the manner implied by the carbon monoxide transfer coefficient (KCO (TL/VA)). This paper considers two other simple models (one linear and one exponential) which might standardize TL for VA, and asks the questions: 1) Is either model valid? 2) What are appropriate reference values? and 3) Will the model be useful? The relationship of TL to VA within subjects at different depths of inspiration, and between subjects having lungs of different sizes, were measured and compared. The subjects were asymptomatic, nonsmoking, Caucasian adults, including 31 males assessed in the laboratory and 503 male and female participants in population studies. The linear partial regression coefficients of TL on VA (L corrected for body temperature, atmospheric pressure and water saturation (BTPS)) standardized for height (H) in metres, were similar within- and between-subjects; the coefficients applied over a wide range of values for VA. This was not the case for the exponential model. The resulting reference equations in SI units for males and females were: TL = 11.52 H + 2.72 VA.H-2 - 0.051 Age -12.35. RSD 1.17; and TL = 4.87 H + 2.29 VA.H-2 - 0.019 Age -3.03. RSD 0.92, respectively. The residual standard deviations (RSD) about the new relationships were less than in other series. The new linear model could account for much of the variation between different published reference values for TL; it could be useful clinically, in circumstances when VA deviates from the norm. The model does not explain differences in TL associated with gender. Inclusion of VA.H-2 as a covariate in the reference equation for transfer factor, in addition to age and height, improves the accuracy of prediction of normal transfer factor compared with current reference values; its use suggests that some of the differences between published values is due to the volume term. The equations can be used clinically, and eliminate the need for carbon

  5. Herbal reference standards.

    Science.gov (United States)

    Schwarz, Michael; Klier, Bernhard; Sievers, Hartwig

    2009-06-01

    This review describes the current definitions and regulatory requirements that apply to reference standards that are used to analyse herbal products. It also describes and discusses the current use of reference substances and reference extracts in the European and United States pharmacopoeias.

  6. Study on the Preparation and Application of Cannabis Fructus TLC Reference Extract%火麻仁薄层色谱鉴别用对照提取物的研制与应用

    Institute of Scientific and Technical Information of China (English)

    邓仕任; 蔡明宸; 夏林波; 王鑫; 朱夏敏

    2016-01-01

    Cannabis fructus TLC reference extract was prepared and its application in the quality control of Cannabis fructus and preparations as a reference drug was explored.Cannabis fructus TLC reference extract was prepared by opting processing route and investigating stability influencing factors.The application to TLC identification items of Cannabis fructus was performed according to the Chinese Pharmacopoeia 2010 edition.Results showed that Cannabis fructus TLC reference extract can play the same role as Cannabis fructus reference drug with the same quantity and quality.Cannabis fructus TLC reference extract for TLC identification can be used for quality control analysis of Cannabis fructus and preparations.The research provided a foundation for further development of TCM reference extracts.%研制被薄层色谱鉴别用火麻仁对照提取物,以替代对照药材用于火麻仁的薄层鉴别。从制备工艺考察、提取物稳定性影响因素考察以及提取物性状等方面制订薄层色谱鉴别用火麻仁对照提取物的制备和保存方法,并比较对照药材与对照提取物在薄层鉴别中的应用结果。结果表明:制备方法为:火麻仁药材粉末(过二号筛)加25倍乙醚脱脂后,药渣加10倍甲醇加热回流提取1 h,滤过,减压蒸去甲醇,所得浸膏用10倍甲醇复溶,加入与浸膏等重量的柱层析硅胶(200~300目),混匀,减压蒸干甲醇,过九号筛即得。该对照提取物与火麻仁药材的薄层鉴别效果一致。本研究制备的火麻仁薄层鉴别用对照提取物稳定可靠,可以替代火麻仁对照药材用于火麻仁及其成方制剂的质量控制分析。

  7. A reference-modified density functional theory: An application to solvation free-energy calculations for a Lennard-Jones solution.

    Science.gov (United States)

    Sumi, Tomonari; Maruyama, Yutaka; Mitsutake, Ayori; Koga, Kenichiro

    2016-06-14

    In the conventional classical density functional theory (DFT) for simple fluids, an ideal gas is usually chosen as the reference system because there is a one-to-one correspondence between the external field and the density distribution function, and the exact intrinsic free-energy functional is available for the ideal gas. In this case, the second-order density functional Taylor series expansion of the excess intrinsic free-energy functional provides the hypernetted-chain (HNC) approximation. Recently, it has been shown that the HNC approximation significantly overestimates the solvation free energy (SFE) for an infinitely dilute Lennard-Jones (LJ) solution, especially when the solute particles are several times larger than the solvent particles [T. Miyata and J. Thapa, Chem. Phys. Lett. 604, 122 (2014)]. In the present study, we propose a reference-modified density functional theory as a systematic approach to improve the SFE functional as well as the pair distribution functions. The second-order density functional Taylor series expansion for the excess part of the intrinsic free-energy functional in which a hard-sphere fluid is introduced as the reference system instead of an ideal gas is applied to the LJ pure and infinitely dilute solution systems and is proved to remarkably improve the drawbacks of the HNC approximation. Furthermore, the third-order density functional expansion approximation in which a factorization approximation is applied to the triplet direct correlation function is examined for the LJ systems. We also show that the third-order contribution can yield further refinements for both the pair distribution function and the excess chemical potential for the pure LJ liquids.

  8. Ecological Evaluation Index continuous formula (EEI-c application: a step forward for functional groups, the formula and reference condition values

    Directory of Open Access Journals (Sweden)

    S. ORFANIDIS

    2012-12-01

    Full Text Available The Ecological Evaluation Index continuous formula (EEI-c was designed to estimate the habitat- based ecological status of rocky coastal and sedimentary transitional waters using shallow benthic macrophyte communities as bioindicators. This study aimed to remedy the weaknesses of the currently used EEI methodology in: (1 ecological status groups (ESG, (2 the formula, and (3 reference condition values. A cluster analysis of twelve species traits was used to delineate ESGs. Two main clusters (ESG I, late-successional; ESG II, opportunistic were identified that were hierarchically divided into three and two sub-clusters, respectively: ESG I comprised thick perennial (IA, thick plastic (IB and shade-adapted plastic (IC coastal water species, and angiosperm plastic (IA, thick plastic (IB and shade-adapted plastic (IC transitional water species. ESG II comprised fleshy opportunistic (IIB and filamentous sheet-like opportunistic (IIA species both in coastal and transitional waters. To avoid discrete jumps at the boundaries between predefined ecological categories, a hyperbolic model that approximates the index values and expresses the ecosystem status in continuous numbers was developed. Seventy-four quantitative and destructive samples of the upper infralittoralCystoseira crinita and coastal lagoonRuppia cirrhosa communities from tentative pristine to less impacted sites in Greece verified 10 as an ‘ideal’ EEI-c reference condition value.

  9. CONSTRUCTION OF THE REFERENCE DATABASE IN GBDB AND ITS APPLICATION%GBDB的在线文献数据库及其应用

    Institute of Scientific and Technical Information of China (English)

    樊隽轩; 侯旭东; 陈清; 张琳娜; 陈中阳

    2012-01-01

    The Geobiodiversity Database (GBDB, ht-tp://www. geobiodiversity. com) is a unique, section-based online database system for palaeontolo-gical and stratigraphic research. Various kinds of data sources can be integrated into it, including geographic, lithostratigraphic, biostratigraphic, chronostratigraphic, taxonomic and related bibliographic reference data. Data sources are mostly taken from the published literature. The reference database is therefore an important data source in GBDB. Through the reference database users can track the source of the data, check and verify its quality, and even attach their own opinions, as an important comparison with the initiator' s thoughts. To achieve a comprehensive reference database is a long-term and time-consuming job. As more people become involved, the less time will be consumed per person and the more rapidly data quality will increase. After four years' development, the present reference database is well integrated in GBDB, and eight major reference types are recognized. Both DOI (Digital Object unique Identifier) and URL (Uniform / Universal Resource Locator) automatic conversion to full-text database are supported. Users can upload their Endnote files to the GBDB reference database through the database administrator (fanjunxuan@ gmail. com). A new export function to 12 common journals such as Palaeontology , Journal of Paleontology, Palaeo3, and Acta Palaeontologica Sinica , has recently become available online. By Feb. 15, 2012, 44 310 literature records related to palaeontology and stratigraphy had been compiled into the GBDB. Amongst them, 4 321 were based on material from China, which, according to our preliminary estimation, comprises about one third of the total literature on Chinese material. Simple counting of literature published in each decade since 1900 indicates a slow increase from 1910-1919 to 1950-1959, except for a slight decrease probably resulting from the 2nd World War. Then there was a rapid

  10. Visual Basic 2012 programmer's reference

    CERN Document Server

    Stephens, Rod

    2012-01-01

    The comprehensive guide to Visual Basic 2012 Microsoft Visual Basic (VB) is the most popular programming language in the world, with millions of lines of code used in businesses and applications of all types and sizes. In this edition of the bestselling Wrox guide, Visual Basic expert Rod Stephens offers novice and experienced developers a comprehensive tutorial and reference to Visual Basic 2012. This latest edition introduces major changes to the Visual Studio development platform, including support for developing mobile applications that can take advantage of the Windows 8 operating system

  11. Dynamic HTML The Definitive Reference

    CERN Document Server

    Goodman, Danny

    2007-01-01

    Packed with information on the latest web specifications and browser features, this new edition is your ultimate one-stop resource for HTML, XHTML, CSS, Document Object Model (DOM), and JavaScript development. Here is the comprehensive reference for designers of Rich Internet Applications who need to operate in all modern browsers, including Internet Explorer 7, Firefox 2, Safari, and Opera. With this book, you can instantly see browser support for the latest standards-based technologies, including CSS Level 3, DOM Level 3, Web Forms 2.0, XMLHttpRequest for AJAX applications, JavaScript 1.7

  12. Application of genotyping-by-sequencing on semiconductor sequencing platforms: A comparison of genetic and reference-based marker ordering in barley

    Science.gov (United States)

    The rapid development of next generation sequencing platforms has enabled the use of sequencing for routine genotyping across a range of genetics studies and breeding applications. Genotyping-by-sequencing (GBS), a low-cost, reduced representation sequencing method, is becoming a common approach fo...

  13. Dynamic modeling of breast tissue with application of model reference adaptive system identification technique based on clinical robot-assisted palpation.

    Science.gov (United States)

    Keshavarz, M; Mojra, A

    2015-11-01

    Accurate identification of breast tissue's dynamic behavior in physical examination is critical to successful diagnosis and treatment. In this study a model reference adaptive system identification (MRAS) algorithm is utilized to estimate the dynamic behavior of breast tissue from mechanical stress-strain datasets. A robot-assisted device (Robo-Tac-BMI) is going to mimic physical palpation on a 45 year old woman having a benign mass in the left breast. Stress-strain datasets will be collected over 14 regions of both breasts in a specific period of time. Then, a 2nd order linear model is adapted to the experimental datasets. It was confirmed that a unique dynamic model with maximum error about 0.89% is descriptive of the breast tissue behavior meanwhile mass detection may be achieved by 56.1% difference from the normal tissue.

  14. [Application and case analysis on the problem-based teaching of Jingluo Shuxue Xue (Science of Meridian and Acupoint) in reference to the team oriented learning method].

    Science.gov (United States)

    Ma, Ruijie; Lin, Xianming

    2015-12-01

    The problem based teaching (PBT) has been the main approach to the training in the universities o the world. Combined with the team oriented learning method, PBT will become the method available to the education in medical universities. In the paper, based on the common questions in teaching Jingluo Shuxue Xue (Science of Meridian and Acupoint), the concepts and characters of PBT and the team oriented learning method were analyzed. The implementation steps of PBT were set up in reference to the team oriented learning method. By quoting the original text in Beiji Qianjin Yaofang (Essential recipes for emergent use worth a thousand gold), the case analysis on "the thirteen devil points" was established with PBT.

  15. Application of Google Scholar in Consulting and Citing References%Google Scholar在参考文献查引中的应用

    Institute of Scientific and Technical Information of China (English)

    陈小华

    2016-01-01

    From the editors of sci-tech periodical and authors point of view, the paper discusses the specific steps to consult and cite references, perfect and proofread their recording contents, collect citing number of times for theses. It also analyzes the possible problems and their solutions in the process of operation.%从科技期刊编辑和论文撰写者的视角,文章论述了利用Google Scholar来从事参考文献的查找、引用,参考文献著录内容的完善与校对,论文被引用次数的搜集等工作的具体步骤,并分析了操作过程中可能遇到的问题及其解决办法。

  16. So You Want To Do Virtual Reference?

    Science.gov (United States)

    Coffman, Steve

    2001-01-01

    Examines the practical details of setting up live online reference services in libraries. Topics include choosing software; differences between licensed and hosted applications; models used to implement virtual reference services; how libraries are using these services in day to day operations; and marketing strategies. (Author/LRW)

  17. Android quick APIs reference

    CERN Document Server

    Cinar, Onur

    2015-01-01

    The Android Quick APIs Reference is a condensed code and APIs reference for the new Google Android 5.0 SDK. It presents the essential Android APIs in a well-organized format that can be used as a handy reference. You won't find any technical jargon, bloated samples, drawn out history lessons, or witty stories in this book. What you will find is a software development kit and APIs reference that is concise, to the point and highly accessible. The book is packed with useful information and is a must-have for any mobile or Android app developer or programmer. In the Android Quick APIs Refe

  18. Workplace Ergonomics Reference Guide

    Science.gov (United States)

    Workplace Ergonomics Reference Guide 2 nd Edition A Publication of the Computer/Electronic Accommodations Program Real Solutions for Real ... Table of Contents.................................................................................................................................. ... Checklist ........................................................................................................................... 3 Ergonomic ...

  19. Application of the ICRP/ICRU reference computational phantoms to internal dosimetry: calculation of specific absorbed fractions of energy for photons and electrons.

    Science.gov (United States)

    Hadid, L; Desbrée, A; Schlattl, H; Franck, D; Blanchardon, E; Zankl, M

    2010-07-07

    The emission of radiation from a contaminated body region is connected with the dose received by radiosensitive tissue through the specific absorbed fractions (SAFs) of emitted energy, which is therefore an essential quantity for internal dose assessment. A set of SAFs were calculated using the new adult reference computational phantoms, released by the International Commission on Radiological Protection (ICRP) together with the International Commission on Radiation Units and Measurements (ICRU). Part of these results has been recently published in ICRP Publication 110 (2009 Adult reference computational phantoms (Oxford: Elsevier)). In this paper, we mainly discuss the results and also present them in numeric form. The emission of monoenergetic photons and electrons with energies ranging from 10 keV to 10 MeV was simulated for three source organs: lungs, thyroid and liver. SAFs were calculated for four target regions in the body: lungs, colon wall, breasts and stomach wall. For quality assurance purposes, the simulations were performed simultaneously at the Helmholtz Zentrum München (HMGU, Germany) and at the Institute for Radiological Protection and Nuclear Safety (IRSN, France), using the Monte Carlo transport codes EGSnrc and MCNPX, respectively. The comparison of results shows overall agreement for photons and high-energy electrons with differences lower than 8%. Nevertheless, significant differences were found for electrons at lower energy for distant source/target organ pairs. Finally, the results for photons were compared to the SAF values derived using mathematical phantoms. Significant variations that can amount to 200% were found. The main reason for these differences is the change of geometry in the more realistic voxel body models. For electrons, no SAFs have been computed with the mathematical phantoms; instead, approximate formulae have been used by both the Medical Internal Radiation Dose committee (MIRD) and the ICRP due to the limitations imposed

  20. Application of the ICRP/ICRU reference computational phantoms to internal dosimetry: calculation of specific absorbed fractions of energy for photons and electrons

    Science.gov (United States)

    Hadid, L.; Desbrée, A.; Schlattl, H.; Franck, D.; Blanchardon, E.; Zankl, M.

    2010-07-01

    The emission of radiation from a contaminated body region is connected with the dose received by radiosensitive tissue through the specific absorbed fractions (SAFs) of emitted energy, which is therefore an essential quantity for internal dose assessment. A set of SAFs were calculated using the new adult reference computational phantoms, released by the International Commission on Radiological Protection (ICRP) together with the International Commission on Radiation Units and Measurements (ICRU). Part of these results has been recently published in ICRP Publication 110 (2009 Adult reference computational phantoms (Oxford: Elsevier)). In this paper, we mainly discuss the results and also present them in numeric form. The emission of monoenergetic photons and electrons with energies ranging from 10 keV to 10 MeV was simulated for three source organs: lungs, thyroid and liver. SAFs were calculated for four target regions in the body: lungs, colon wall, breasts and stomach wall. For quality assurance purposes, the simulations were performed simultaneously at the Helmholtz Zentrum München (HMGU, Germany) and at the Institute for Radiological Protection and Nuclear Safety (IRSN, France), using the Monte Carlo transport codes EGSnrc and MCNPX, respectively. The comparison of results shows overall agreement for photons and high-energy electrons with differences lower than 8%. Nevertheless, significant differences were found for electrons at lower energy for distant source/target organ pairs. Finally, the results for photons were compared to the SAF values derived using mathematical phantoms. Significant variations that can amount to 200% were found. The main reason for these differences is the change of geometry in the more realistic voxel body models. For electrons, no SAFs have been computed with the mathematical phantoms; instead, approximate formulae have been used by both the Medical Internal Radiation Dose committee (MIRD) and the ICRP due to the limitations imposed

  1. A strategy for designing multi-taxa specific reference gene systems. example of application--ppi phosphofructokinase (ppi-PPF) used for the detection and quantification of three taxa: maize (Zea mays), cotton (Gossypium hirsutum) and rice (Oryza sativa).

    Science.gov (United States)

    Chaouachi, Maher; Giancola, Sandra; Romaniuk, Marcel; Laval, Valérie; Bertheau, Yves; Brunel, Dominique

    2007-10-03

    In the first part of the paper, we report the description of a new strategy for the development of a plant reference gene system that can be used for genetically modified organism (GMO) analysis. On the basis of in silico research for candidate genes, the design of degenerate primers allowed the obtention of genomic sequences of the selected gene ppi-phosphofructokinase ( ppi-PPF) for nine taxa in which GMOs have been developed. The comparison and the analysis of inter- and intraspecies sequence variability were performed using a large number of species and cultivars. As an example of application following the detection of single nucleotide polymorphism, we designed specific conventional and real-time polymerase chain reaction tests for the detection and quantification of three taxa, namely, maize, cotton, and rice. This system was highly specific and sensitive. The gene copy number conservation among different cultivars was analyzed and confirmed with a sequencing step. This reference gene system is adequate for use in routine assays for the quantification of GMOs. We then explain briefly the constraints faced and propose recommendations when designing a reference gene system depending on the species to be targeted.

  2. Application of USCRN Station Density Strategy to China Climate Reference Network%USCRN气候基准站网布局理论在我国的应用

    Institute of Scientific and Technical Information of China (English)

    胡婷; 周江兴; 代刊

    2012-01-01

    基于美国气候基准站网(USCRN,US Climate Reference Network)的均匀正三角网格布局模式,以站网对我国平均降水量和气温的方差解释量分别能够达到95%和98%为标准,利用我国2416个观测站的降水量和气温数据研究了我国气候观测站网的布局设计,得到能反映我国整体气候特征的站网最少台站数.结果表明:为显著减少全国尺度上的气候不确定性,需要新建边长为3°纬距的正三角均匀网格(103个站点)站网,并在全国范围内开展站址考察、总结评估和运行检验工作,才能得到新的气候基准站网;在已有气候观测系统基础上改进完善而不新建系统,则改进的气候基准站网为最接近边长为2°纬距的正三角网格分布(229个站点),其中199个预期位置或其附近已建有观测站点,没有对应实际站点的30个预期位置主要分布在青藏高原西南大部,这些地区将是未来建站的重点.%The US Climate Reference Network (USCRN) consists of 114 stations developed, deployed, managed, and maintained by the National Oceanic and Atmospheric Administration (NOAA) in the continental United States for the express purpose of detecting the national signal of climate change, focusing solely on precipitation and temperature. The vision of the USCRN program is to reduce uncertainty and error range envelopes in producing the most precise in situ precipitation and temperature records possible, and to do it with the fewest possible stations located in areas of minimal human disturbance and with the least likelihood of human development over the coming 50-100 years. And the key goal of USCRN is to reduce cli-mate uncertainty at the national level to a statistically insignificant level. That is, for precipitation climate uncertainty should be reduced by 95% and for temperature climate uncertainty at the national level should be reduced by 98%.China is in great need of a sustainable high-quality and long

  3. Evaluation of the Penman-Monteith (FAO 56 PM Method for Calculating Reference Evapotranspiration Using Limited Data: Application to the Wet Páramo of Southern Ecuador

    Directory of Open Access Journals (Sweden)

    Mario Córdova

    2015-08-01

    Full Text Available Reference evapotranspiration (ETo is often calculated using the Penman-Monteith (FAO 56 PM; Allen et al 1998 method, which requires data on temperature, relative humidity, wind speed, and solar radiation. But in high-mountain environments, such as the Andean páramo, meteorological monitoring is limited and high-quality data are scarce. Therefore, the FAO 56 PM equation can be applied only through the use of an alternative method suggested by the same authors that substitutes estimates for missing data. This study evaluated whether the FAO 56 PM method for estimating missing data can be effectively used for páramo landscapes in the high Andes of southern Ecuador. Our investigation was based on data from 2 automatic weather stations at elevations of 3780 m and 3979 m. We found that using estimated wind speed data has no major effect on calculated ETo but that if solar radiation data are estimated, ETo calculations may be erroneous by as much as 24%; if relative humidity data are estimated, the error may be as high as 14%; and if all data except temperature are estimated, errors higher than 30% may result. Our study demonstrates the importance of using high-quality meteorological data for calculating ETo in the wet páramo landscapes of southern Ecuador.

  4. Organomercury determination in biological reference materials: application to a study on mercury speciation in marine mammals off the Faröe Islands.

    Science.gov (United States)

    Schintu, M; Jean-Caurant, F; Amiard, J C

    1992-08-01

    The potential use of graphite furnace atomic absorption spectrometry (GF-AAS) for the organic mercury determination in marine biological tissues was evaluated. Following its isolation by acid extraction in toluene, organic mercury was recovered in aqueous thiosulfate and measured by GF-AAS. The detection limit was 0.01 microgram Hg/g (as methyl mercury). Analyses were conducted on three reference standard materials certified for their methyl mercury content, DOLT-1, DORM-1, and TORT-1, provided by the National Research Council of Canada. The method resulted in very good recovery and reproducibility, indicating that GF-AAS can provide results comparable to those obtained by using more expensive and time consuming analytical techniques. The method was applied to the analysis of liver tissues of pilot whale specimens (Globicephala melas) from the drive fishery of the Faröe Islands (northeast Atlantic). The results provided useful information on the proportion of different mercury forms in the liver of these marine mammals.

  5. Creation and application of voxelised dosimetric models, and a comparison with the current methodology as used for the International Commission on Radiological Protection's Reference Animals and Plants.

    Science.gov (United States)

    Higley, K; Ruedig, E; Gomez-Fernandez, M; Caffrey, E; Jia, J; Comolli, M; Hess, C

    2015-06-01

    Over the past decade, the International Commission on Radiological Protection (ICRP) has developed a comprehensive approach to environmental protection that includes the use of Reference Animals and Plants (RAPs) to assess radiological impacts on the environment. For the purposes of calculating radiation dose, the RAPs are approximated as simple shapes that contain homogeneous distributions of radionuclides. As uncertainties in environmental dose effects are larger than uncertainties in radiation dose calculation, some have argued against more realistic dose calculation methodologies. However, due to the complexity of organism morphology, internal structure, and density, dose rates calculated via a homogenous model may be too simplistic. The purpose of this study is to examine the benefits of a voxelised phantom compared with simple shapes for organism modelling. Both methods typically use Monte Carlo methods to calculate absorbed dose, but voxelised modelling uses an exact three-dimensional replica of an organism with accurate tissue composition and radionuclide source distribution. It is a multi-stage procedure that couples imaging modalities and processing software with Monte Carlo N-Particle. These features increase dosimetric accuracy, and may reduce uncertainty in non-human biota dose-effect studies by providing mechanistic answers regarding where and how population-level dose effects arise.

  6. Submergence Vulnerability Index development and application to Coastwide Reference Monitoring System Sites and Coastal Wetlands Planning, Protection and Restoration Act projects

    Science.gov (United States)

    Stagg, Camille L.; Sharp, Leigh Anne; McGinnis, Thomas E.; Snedden, Gregg A.

    2013-01-01

    Since its implementation in 2003, the Coastwide Reference Monitoring System (CRMS) in Louisiana has facilitated the creation of a comprehensive dataset that includes, but is not limited to, vegetation, hydrologic, and soil metrics on a coastwide scale. The primary impetus for this data collection is to assess land management activities, including restoration efforts, across the coast. The aim of the CRMS analytical team is to provide a method to synthesize this data to enable multiscaled evaluations of activities in Louisiana’s coastal wetlands. Several indices have been developed to facilitate data synthesis and interpretation, including a Floristic Quality Index, a Hydrologic Index, and a Landscape Index. This document details the development of the Submergence Vulnerability Index, which incorporates sediment-elevation data as well as hydrologic data to determine the vulnerability of a wetland based on its ability to keep pace with sea-level rise. The objective of this document is to provide Federal and State sponsors, project managers, planners, landowners, data users, and the rest of the coastal restoration community with the following: (1) data collection and model development methods for the sediment-elevation response variables, and (2) a description of how these response variables will be used to evaluate CWPPRA project and program effectiveness.

  7. Application of the optimized decoupling methodology for the construction of a skeletal primary reference fuel (PRF mechanism focusing on engine-relevant conditions

    Directory of Open Access Journals (Sweden)

    Yachao eChang

    2015-09-01

    Full Text Available For the multi-dimensional simulation of the engines with advanced compression-ignition combustion strategies, a practical and robust chemical kinetic mechanism is highly demanded. Decoupling methodology is effective for the construction of skeletal mechanisms for long-chain alkanes. To improve the performance of the decoupling methodology, further improvements are introduced based on recent theoretical and experimental works. The improvements include: (1 updating the H2/O2 sub-mechanism; (2 refining the rate constants in the HCO/CH3/CH2O sub-mechanism; (3 building a new reduced C2 sub-mechanism; and (4 improving the large-molecule sub-mechanism. With the improved decoupling methodology, a skeletal primary reference fuel (PRF mechanism is developed. The mechanism is validated against the experimental data in shock tubes, jet-stirred reactors, premixed and counterflow flames for various PRF fuels covering the temperature range of 500–1450 K, the pressure range of 1–55 atm, and the equivalence ratio range of 0.25¬–1.0. Finally, the skeletal mechanism is coupled with a multi-dimensional computational fluid dynamics model to simulate the combustion and emission characteristics of homogeneous charge compression ignition (HCCI engines fueled with iso-octane and PRF. Overall, the agreements between the experiment and prediction are satisfactory.

  8. Aspect and Reference time

    NARCIS (Netherlands)

    Borik, O.

    2002-01-01

    This thesis provides a theory of aspect in Russian based on the notion of Reference time. The main claim advocated in this study is that there are two types of aspect, predicational/telicity aspect and perspective or Reference time aspect. It is argued that these two types should be carefully distin

  9. Reference class forecasting

    DEFF Research Database (Denmark)

    Flyvbjerg, Bent

    optimisme og misinformation. RCF bygger på teorier, som vandt Daniel Kahneman Nobelprisen i økonomi i 2002. RCF estimerer budgettet for et givet projekt på grundlag af de faktiske udfald for budgetterne i en reference-klasse af projekter. RCF udføres i tre trin: 1. Identifikation af en relevant reference...

  10. Marketing Reference Services.

    Science.gov (United States)

    Norman, O. Gene

    1995-01-01

    Relates the marketing concept to library reference services. Highlights include a review of the literature and an overview of marketing, including research, the marketing mix, strategic plan, marketing plan, and marketing audit. Marketing principles are applied to reference services through the marketing mix elements of product, price, place, and…

  11. Rethinking Virtual Reference

    Science.gov (United States)

    Tenopir, Carol

    2004-01-01

    Virtual reference services seem a natural extension of libraries digital collections and the emphasis on access to the library anytime, anywhere. If patrons use the library from home, it makes sense to provide them with person-to-person online reference. The Library of Congress (LC), OCLC, and several large library systems have developed and…

  12. Reference Service Training Manual.

    Science.gov (United States)

    Mielke, John; Young, William

    This manual is primarily designed as an orientation program for librarians new to the Reference Services Division at the State University of New York at Albany University Libraries. It contains practical information and some of the procedures necessary for providing service at the reference desk in these libraries. The appendices provide samples…

  13. China Connections Reference Book.

    Science.gov (United States)

    Kalat, Marie B.; Hoermann, Elizabeth F.

    This reference book focuses on six aspects of the geography of the People's Republic of China. They are: territory, governing units, population and land use, waterways, land forms, and climates. Designed as a primary reference, the book explains how the Chinese people and their lifestyles are affected by China's geography. Special components…

  14. Steady induction effects in geomagnetism. Part 1C: Geomagnetic estimation of steady surficial core motions: Application to the definitive geomagnetic reference field models

    Science.gov (United States)

    Voorhies, Coerte V.

    1993-01-01

    In the source-free mantle/frozen-flux core magnetic earth model, the non-linear inverse steady motional induction problem was solved using the method presented in Part 1B. How that method was applied to estimate steady, broad-scale fluid velocity fields near the top of Earth's core that induce the secular change indicated by the Definitive Geomagnetic Reference Field (DGRF) models from 1945 to 1980 are described. Special attention is given to the derivation of weight matrices for the DGRF models because the weights determine the apparent significance of the residual secular change. The derived weight matrices also enable estimation of the secular change signal-to-noise ratio characterizing the DGRF models. Two types of weights were derived in 1987-88: radial field weights for fitting the evolution of the broad-scale portion of the radial geomagnetic field component at Earth's surface implied by the DGRF's, and general weights for fitting the evolution of the broad-scale portion of the scalar potential specified by these models. The difference is non-trivial because not all the geomagnetic data represented by the DGRF's constrain the radial field component. For radial field weights (or general weights), a quantitatively acceptable explication of broad-scale secular change relative to the 1980 Magsat epoch must account for 99.94271 percent (or 99.98784 percent) of the total weighted variance accumulated therein. Tolerable normalized root-mean-square weighted residuals of 2.394 percent (or 1.103 percent) are less than the 7 percent errors expected in the source-free mantle/frozen-flux core approximation.

  15. Radar rainfall estimation for the post-event analysis of a Slovenian flash-flood case: application of the mountain reference technique at C-band frequency

    Directory of Open Access Journals (Sweden)

    L. Bouilloud

    2009-01-01

    Full Text Available This article is dedicated to radar rainfall estimation for the post-event analysis of a Slovenian flash flood that occurred on 18 September 2007. The utility of the Mountain Reference Technique is demonstrated to quantify rain attenuation effects that affect C-band radar measurements in heavy rain. Maximum path-integrated attenuation between 15 and 20 dB were measured thanks to mountain returns for path-averaged rain rates between 10 and 15 mm h−1 over a 120-km path. The proposed technique allowed estimation of an effective radar calibration correction factor, assuming the reflectivity-attenuation relationship to be known. Screening effects were quantified using a geometrical calculation based on a digitized terrain model of the region. The vertical structure of the reflectivity was modelled with a normalized apparent vertical profile of reflectivity. Implementation of the radar data processing indicated that: (1 attenuation correction using the Hitschfeld Bordan algorithm allowed obtaining satisfactory radar rain estimates (Nash criterion of 0.8 at the event time scale; (2 due to the attenuation equation instability, it is however compulsory to limit the maximum path-integrated attenuation to be corrected to about 10 dB; (3 the results also proved to be sensitive on the parameterization of reflectivity-attenuation-rainrate relationships. The convective nature of the precipitation explains the rather good performance obtained. For more contrasted rainy systems with convective and stratiform regions, the combination of the vertical (VPR and radial (attenuation, screening sources of heterogeneity yields a still very challenging problem for radar quantitative precipitation estimation at C-band.

  16. Collaborating on Referring Expressions

    CERN Document Server

    Heeman, P A; Heeman, Peter A.; Hirst, Graeme

    1995-01-01

    This paper presents a computational model of how conversational participants collaborate in order to make a referring action successful. The model is based on the view of language as goal-directed behavior. We propose that the content of a referring expression can be accounted for by the planning paradigm. Not only does this approach allow the processes of building referring expressions and identifying their referents to be captured by plan construction and plan inference, it also allows us to account for how participants clarify a referring expression by using meta-actions that reason about and manipulate the plan derivation that corresponds to the referring expression. To account for how clarification goals arise and how inferred clarification plans affect the agent, we propose that the agents are in a certain state of mind, and that this state includes an intention to achieve the goal of referring and a plan that the agents are currently considering. It is this mental state that sanctions the adoption of g...

  17. Revisions of the Fish Invasiveness Screening Kit (FISK) for its application in warmer climatic zones, with particular reference to peninsular Florida.

    Science.gov (United States)

    Lawson, Larry L; Hill, Jeffrey E; Vilizzi, Lorenzo; Hardin, Scott; Copp, Gordon H

    2013-08-01

    The initial version (v1) of the Fish Invasiveness Scoring Kit (FISK) was adapted from the Weed Risk Assessment of Pheloung, Williams, and Halloy to assess the potential invasiveness of nonnative freshwater fishes in the United Kingdom. Published applications of FISK v1 have been primarily in temperate-zone countries (Belgium, Belarus, and Japan), so the specificity of this screening tool to that climatic zone was not noted until attempts were made to apply it in peninsular Florida. To remedy this shortcoming, the questions and guidance notes of FISK v1 were reviewed and revised to improve clarity and extend its applicability to broader climatic regions, resulting in changes to 36 of the 49 questions. In addition, upgrades were made to the software architecture of FISK to improve overall computational speed as well as graphical user interface flexibility and friendliness. We demonstrate the process of screening a fish species using FISK v2 in a realistic management scenario by assessing the Barcoo grunter Scortum barcoo (Terapontidae), a species whose management concerns are related to its potential use for aquaponics in Florida. The FISK v2 screening of Barcoo grunter placed the species into the lower range of medium risk (score = 5), suggesting it is a permissible species for use in Florida under current nonnative species regulations. Screening of the Barcoo grunter illustrates the usefulness of FISK v2 as a proactive tool serving to inform risk management decisions, but the low level of confidence associated with the assessment highlighted a dearth of critical information on this species.

  18. CSS Pocket Reference

    CERN Document Server

    Meyer, Eric

    2011-01-01

    When you're working with CSS and need a quick answer, CSS Pocket Reference delivers. This handy, concise book provides all of the essential information you need to implement CSS on the fly. Ideal for intermediate to advanced web designers and developers, the 4th edition is revised and updated for CSS3, the latest version of the Cascading Style Sheet specification. Along with a complete alphabetical reference to CSS3 selectors and properties, you'll also find a short introduction to the key concepts of CSS. Based on Cascading Style Sheets: The Definitive Guide, this reference is an easy-to-us

  19. STL pocket reference

    CERN Document Server

    Lischner, Ray

    2003-01-01

    The STL Pocket Reference describes the functions, classes, and templates in that part of the C++ standard library often referred to as the Standard Template Library (STL). The STL encompasses containers, iterators, algorithms, and function objects, which collectively represent one of the most important and widely used subsets of standard library functionality. The C++ standard library, even the subset known as the STL, is vast. It's next to impossible to work with the STL without some sort of reference at your side to remind you of template parameters, function invocations, return types--ind

  20. Biomedical Engineering Desk Reference

    CERN Document Server

    Ratner, Buddy D; Schoen, Frederick J; Lemons, Jack E; Dyro, Joseph; Martinsen, Orjan G; Kyle, Richard; Preim, Bernhard; Bartz, Dirk; Grimnes, Sverre; Vallero, Daniel; Semmlow, John; Murray, W Bosseau; Perez, Reinaldo; Bankman, Isaac; Dunn, Stanley; Ikada, Yoshito; Moghe, Prabhas V; Constantinides, Alkis

    2009-01-01

    A one-stop Desk Reference, for Biomedical Engineers involved in the ever expanding and very fast moving area; this is a book that will not gather dust on the shelf. It brings together the essential professional reference content from leading international contributors in the biomedical engineering field. Material covers a broad range of topics including: Biomechanics and Biomaterials; Tissue Engineering; and Biosignal Processing* A hard-working desk reference providing all the essential material needed by biomedical and clinical engineers on a day-to-day basis * Fundamentals, key techniques,

  1. R quick syntax reference

    CERN Document Server

    Tollefson, Margot

    2014-01-01

    The R Quick Syntax Reference is a handy reference book detailing the intricacies of the R language. Not only is R a free, open-source tool, R is powerful, flexible, and has state of the art statistical techniques available. With the many details which must be correct when using any language, however, the R Quick Syntax Reference makes using R easier.Starting with the basic structure of R, the book takes you on a journey through the terminology used in R and the syntax required to make R work. You will find looking up the correct form for an expression quick and easy. With a copy of the R Quick

  2. LINQ Pocket Reference

    CERN Document Server

    Albahari, Joseph

    2008-01-01

    Ready to take advantage of LINQ with C# 3.0? This guide has the detail you need to grasp Microsoft's new querying technology, and concise explanations to help you learn it quickly. And once you begin to apply LINQ, the book serves as an on-the-job reference when you need immediate reminders. All the examples in the LINQ Pocket Reference are preloaded into LINQPad, the highly praised utility that lets you work with LINQ interactively. Created by the authors and free to download, LINQPad will not only help you learn LINQ, it will have you thinking in LINQ. This reference explains: LINQ's ke

  3. The Calibration Reference Data System

    Science.gov (United States)

    Greenfield, P.; Miller, T.

    2016-07-01

    We describe a software architecture and implementation for using rules to determine which calibration files are appropriate for calibrating a given observation. This new system, the Calibration Reference Data System (CRDS), replaces what had been previously used for the Hubble Space Telescope (HST) calibration pipelines, the Calibration Database System (CDBS). CRDS will be used for the James Webb Space Telescope (JWST) calibration pipelines, and is currently being used for HST calibration pipelines. CRDS can be easily generalized for use in similar applications that need a rules-based system for selecting the appropriate item for a given dataset; we give some examples of such generalizations that will likely be used for JWST. The core functionality of the Calibration Reference Data System is available under an Open Source license. CRDS is briefly contrasted with a sampling of other similar systems used at other observatories.

  4. Underwater Sound Reference Division

    Data.gov (United States)

    Federal Laboratory Consortium — The Underwater Sound Reference Division (USRD) serves as the U.S. standardizing activity in the area of underwater acoustic measurements, as the National Institute...

  5. Ozone Standard Reference Photometer

    Data.gov (United States)

    Federal Laboratory Consortium — The Standard Reference Photometer (SRP) Program began in the early 1980s as collaboration between NIST and the U.S. Environmental Protection Agency (EPA) to design,...

  6. Reference Climatological Stations

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The Reference Climatological Stations (RCS) network represents the first effort by NOAA to create and maintain a nationwide network of stations located only in areas...

  7. Genetics Home Reference: hypermethioninemia

    Science.gov (United States)

    ... C. Mutations in human glycine N-methyltransferase give insights into its role in methionine metabolism. Hum Genet. ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  8. Toxicity Reference Database

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Toxicity Reference Database (ToxRefDB) contains approximately 30 years and $2 billion worth of animal studies. ToxRefDB allows scientists and the interested...

  9. Review: Satellite-based remote sensing and geographic information systems and their application in the assessment of groundwater potential, with particular reference to India

    Science.gov (United States)

    Jasmin, Ismail; Mallikarjuna, P.

    2011-06-01

    Various hydrological, geological and geomorphological factors play a major role in the occurrence and movement of groundwater in different terrains. With advances in space technology and the advent of powerful personal computers, techniques for the assessment of groundwater potential have evolved, of which remote sensing (RS) and geographic information systems (GIS) are of great significance. The application of these methods is comprehensively reviewed with respect to the exploration and assessment of groundwater potential in consolidated and unconsolidated formations in semi-arid regions, and specifically in India. The process of such assessment includes the collection of remotely sensed data from suitable sensors and the selection of thematic maps on rainfall, geology, lithology, geomorphology, soil, land use/land cover, drainage patterns, slope and lineaments. The data are handled according to their significance with the assignment of appropriate weights and integrated into a sophisticated GIS environment. The requisite remote sensing and GIS data, in conjunction with necessary field investigations, help to identify the groundwater potential zones effectively.

  10. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2012-01-01

    <正>The format for citations in text and for bibliographic references follows GB/T 7714—2005.The citation should be ordered in number as it appears in the text of the submitted article.For journal article Sun,Y.,Li,B.,&Qu,J.F.Design and implementation of library intelligent IM reference robot.New Technology of Library and Information Service(in Chinese),2011,205:88–92.

  11. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2014-01-01

    <正>The format for citations in text and for bibliographic references follows GB/T 7714—2005.The citation should be ordered in number as it appears in the text of the submitted article.For journal article Sun,Y.,Li,B.,&Qu,J.F.Design and implementation of library intelligent IM reference robot.New Technology of Library and Information Service(in Chinese),

  12. Reference Based Genome Compression

    OpenAIRE

    Chern, Bobbie; Ochoa, Idoia; Manolakos, Alexandros; No, Albert; Venkat, Kartik; Weissman, Tsachy

    2012-01-01

    DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while viable, cannot offer the same savings as approaches tuned to inherent biological properties. We propose an algorithm to compress a target genome given a known reference genome. The proposed algorithm first generates a mapping from the reference to the target gen...

  13. Reference Man anatomical model

    Energy Technology Data Exchange (ETDEWEB)

    Cristy, M.

    1994-10-01

    The 70-kg Standard Man or Reference Man has been used in physiological models since at least the 1920s to represent adult males. It came into use in radiation protection in the late 1940s and was developed extensively during the 1950s and used by the International Commission on Radiological Protection (ICRP) in its Publication 2 in 1959. The current Reference Man for Purposes of Radiation Protection is a monumental book published in 1975 by the ICRP as ICRP Publication 23. It has a wealth of information useful for radiation dosimetry, including anatomical and physiological data, gross and elemental composition of the body and organs and tissues of the body. The anatomical data includes specified reference values for an adult male and an adult female. Other reference values are primarily for the adult male. The anatomical data include much data on fetuses and children, although reference values are not established. There is an ICRP task group currently working on revising selected parts of the Reference Man document.

  14. PVWatts Version 1 Technical Reference

    Energy Technology Data Exchange (ETDEWEB)

    Dobos, A. P.

    2013-10-01

    The NREL PVWatts(TM) calculator is a web application developed by the National Renewable Energy Laboratory (NREL) that estimates the electricity production of a grid-connected photovoltaic system based on a few simple inputs. PVWatts combines a number of sub-models to predict overall system performance, and makes several hidden assumptions about performance parameters. This technical reference details the individual sub-models, documents assumptions and hidden parameters, and explains the sequence of calculations that yield the final system performance estimation.

  15. Establishing ecological reference conditions and tracking post-application effectiveness of lanthanum-saturated bentonite clay (Phoslock®) for reducing phosphorus in aquatic systems: an applied paleolimnological approach.

    Science.gov (United States)

    Moos, M T; Taffs, K H; Longstaff, B J; Ginn, B K

    2014-08-01

    Innovative management strategies for nutrient enrichment of freshwater are important in the face of this increasing global problem, however many strategies are not assessed over long enough time periods to establish effectiveness. Paleolimnological techniques using diatoms as biological indicators were utilized to establish ecological reference conditions, environmental variation, and the effectiveness of lanthanum-saturated bentonite clay (brand name: Phoslock(®)) applied to reduce water column phosphorus (P) concentrations in four waterbodies in Ontario, Canada, and eastern Australia. In sediment cores from the two Canadian sites, there were short-lived changes to diatom assemblages, relative to inferred background conditions, and a temporary reduction in both measured and diatom-inferred total phosphorus (TP) before returning to pre-application conditions (particularly in the urban stormwater management pond which has a high flushing rate and responds rapidly to precipitation and surface run-off). The two Australian sites (a sewage treatment pond and a shallow recreational lake), recorded no reduction in diatom-inferred TP. Based on our pre-application environmental reconstruction, changes to the diatom assemblages and diatom-inferred TP appeared to be driven by larger, climatic factors. While laboratory tests involving this product showed sharp reductions in water column TP, management strategies require detailed information on pre-application environmental conditions and variations in order to accurately assess the effectiveness of new technologies for lake management.

  16. Application of EndNote Software in Medical Reference Management and Paper Writing%EndNote 软件在医学文献管理和论文写作中的应用

    Institute of Scientific and Technical Information of China (English)

    陈丽华; 张戎; 方亮; 张赟; 金伯泉

    2015-01-01

    Referring to the specific characteristics of medical scientific research ,we introduce the basic knowledge as well as using methods ,technical advantages and disadvantages of Endnote software in the management of medical reference and paper w riting ,aiming to promote its application in medical scientific research in order to facilitate medical scientific research .%结合医学科研工作的具体特点,介绍了EndNote软件的基本知识及其在医学文献管理和论文写作中的运用方法、技术优势和不足之处,旨在使包括研究生在内的医学科研工作者能够在医学科研工作中更好地应用EndNote软件,为其有效地进行医学科研工作打下基础。

  17. Validation of 24-Hour Posaconazole and Voriconazole MIC Readings versus the CLSI 48-Hour Broth Microdilution Reference Method: Application of Epidemiological Cutoff Values to Results from a Global Candida Antifungal Surveillance Program▿

    Science.gov (United States)

    Pfaller, M. A.; Boyken, L. B.; Hollis, R. J.; Kroeger, J.; Messer, S. A.; Tendolkar, S.; Diekema, D. J.

    2011-01-01

    We performed 24- and 48-h MIC determinations of posaconazole and voriconazole against more than 16,000 clinical isolates of Candida species. By using the 24- and 48-h epidemiological cutoff values (ECVs), the categorical agreement between the 24-h and reference 48-h broth microdilution results ranged from 97.1% (C. parapsilosis and voriconazole) to 99.8% (C. krusei and voriconazole), with 0.0 to 2.9% very major discrepancies (VMD). The essential agreement (within 2 log2 dilutions) between the 24- and 48-h results was 99.6% for both posaconazole and voriconazole. The MIC results obtained for both posaconazole and voriconazole after only 24 h of incubation may be used to determine the susceptibilities of Candida spp. to these important antifungal agents. The applications of ECVs to this large collection of Candida isolates suggests the potential to develop 24-h species-specific clinical breakpoints for both posaconazole and voriconazole. PMID:21289155

  18. New celestial reference system

    Science.gov (United States)

    Seidelmann, P. K.; Kaplan, G. H.; van Flandern, T. C.

    It is pointed out that the IAU (1976) System of Astronomical Constants, the FK5 and new lunar and planetary theories are being introduced in 1984. The investigation and planning for the transition have revealed the complex interdependencies between observational techniques and the reference systems and their strong link to the rotating and orbiting earth. Details for the conversion to the new system are given. The concepts for a future reference system are developed, based on separating the real motions involved in such a way that observations from various moving platforms can be related to the appropriate coordinate system without involving motions that are not intrinsically involved in the observations. As a consequence, the reference systems determined or used in space, while affected by aberration and parallax, would logically be defined with no dependence on precession, nutation, polar motion, or Universal Time, all of which are concerned with motions of the earth's surface.

  19. Setting reference targets

    Energy Technology Data Exchange (ETDEWEB)

    Ruland, R.E.

    1997-04-01

    Reference Targets are used to represent virtual quantities like the magnetic axis of a magnet or the definition of a coordinate system. To explain the function of reference targets in the sequence of the alignment process, this paper will first briefly discuss the geometry of the trajectory design space and of the surveying space, then continue with an overview of a typical alignment process. This is followed by a discussion on magnet fiducialization. While the magnetic measurement methods to determine the magnetic centerline are only listed (they will be discussed in detail in a subsequent talk), emphasis is given to the optical/mechanical methods and to the task of transferring the centerline position to reference targets.

  20. Reference Based Genome Compression

    CERN Document Server

    Chern, Bobbie; Manolakos, Alexandros; No, Albert; Venkat, Kartik; Weissman, Tsachy

    2012-01-01

    DNA sequencing technology has advanced to a point where storage is becoming the central bottleneck in the acquisition and mining of more data. Large amounts of data are vital for genomics research, and generic compression tools, while viable, cannot offer the same savings as approaches tuned to inherent biological properties. We propose an algorithm to compress a target genome given a known reference genome. The proposed algorithm first generates a mapping from the reference to the target genome, and then compresses this mapping with an entropy coder. As an illustration of the performance: applying our algorithm to James Watson's genome with hg18 as a reference, we are able to reduce the 2991 megabyte (MB) genome down to 6.99 MB, while Gzip compresses it to 834.8 MB.

  1. HTML & XHTML Pocket Reference

    CERN Document Server

    Robbins, Jennifer

    2010-01-01

    After years of using spacer GIFs, layers of nested tables, and other improvised solutions for building your web sites, getting used to the more stringent standards-compliant design can be intimidating. HTML and XHTML Pocket Reference is the perfect little book when you need answers immediately. Jennifer Niederst-Robbins, author Web Design in a Nutshell, has revised and updated the fourth edition of this pocket guide by taking the top 20% of vital reference information from her Nutshell book, augmenting it judiciously, cross-referencing everything, and organizing it according to the most com

  2. Perl Pocket Reference

    CERN Document Server

    Vromans, Johan

    2011-01-01

    If you have a Perl programming question, you'll find the answer quickly in this handy, easy-to-use quick reference. The Perl Pocket Reference condenses and organizes stacks of documentation down to the most essential facts, so you can find what you need in a heartbeat. Updated for Perl 5.14, the 5th edition provides a summary of Perl syntax rules and a complete list of operators, built-in functions, and other features. It's the perfect companion to O'Reilly's authoritative and in-depth Perl programming books, including Learning Perl, Programming Perl, and the Perl Cookbook..

  3. Python pocket reference

    CERN Document Server

    Lutz, Mark

    2010-01-01

    This is the book to reach for when you're coding on the fly and need an answer now. It's an easy-to-use reference to the core language, with descriptions of commonly used modules and toolkits, and a guide to recent changes, new features, and upgraded built-ins -- all updated to cover Python 3.X as well as version 2.6. You'll also quickly find exactly what you need with the handy index. Written by Mark Lutz -- widely recognized as the world's leading Python trainer -- Python Pocket Reference, Fourth Edition, is the perfect companion to O'Reilly's classic Python tutorials, also written by Mark

  4. CSS Pocket Reference

    CERN Document Server

    Meyer, Eric A

    2007-01-01

    They say that good things come in small packages, and it's certainly true for this edition of CSS Pocket Reference. Completely revised and updated to reflect the latest Cascading Style Sheet specifications in CSS 2.1, this indispensable little book covers the most essential information that web designers and developers need to implement CSS effectively across all browsers. Inside, you'll find: A short introduction to the key concepts of CSS A complete alphabetical reference to all CSS 2.1 selectors and properties A chart displaying detailed information about CSS support for every style ele

  5. bash Quick Reference

    CERN Document Server

    Robbins, Arnold

    2008-01-01

    In this quick reference, you'll find everything you need to know about the bash shell. Whether you print it out or read it on the screen, this PDF gives you the answers to the annoying questions that always come up when you're writing shell scripts: What characters do you need to quote? How do you get variable substitution to do exactly what you want? How do you use arrays? It's also helpful for interactive use. If you're a Unix user or programmer, or if you're using bash on Windows, you'll find this quick reference indispensable.

  6. References on Sustainable Buildings

    OpenAIRE

    2005-01-01

    This web site is developed with the aim to promote sustainable design and planning of buildings. Selected references including books, reports, audio/visual materials and journals are listed. Most of the materials can be found in the HKU Libraries. To facilitate retrieval, links are provided to the library catalogue system for further information and study.

  7. Reference-Dependent Sympathy

    Science.gov (United States)

    Small, Deborah A.

    2010-01-01

    Natural disasters and other traumatic events often draw a greater charitable response than do ongoing misfortunes, even those that may cause even more widespread misery, such as famine or malaria. Why is the response disproportionate to need? The notion of reference dependence critical to Prospect Theory (Kahneman & Tversky, 1979) maintains that…

  8. The Reference Encounter Model.

    Science.gov (United States)

    White, Marilyn Domas

    1983-01-01

    Develops model of the reference interview which explicitly incorporates human information processing, particularly schema ideas presented by Marvin Minsky and other theorists in cognitive processing and artificial intelligence. Questions are raised concerning use of content analysis of transcribed verbal protocols as methodology for studying…

  9. Selecting a Reference Object

    Science.gov (United States)

    Miller, Jared E.; Carlson, Laura A.; Hill, Patrick L.

    2011-01-01

    One way to describe the location of an object is to relate it to another object. Often there are many nearby objects, each of which could serve as a candidate to be the reference object. A common theoretical assumption is that features that make a given object salient relative to the candidate set are instrumental in determining which is selected.…

  10. Virtual Reference Services.

    Science.gov (United States)

    Brewer, Sally

    2003-01-01

    As the need to access information increases, school librarians must create virtual libraries. Linked to reliable reference resources, the virtual library extends the physical collection and library hours and lets students learn to use Web-based resources in a protected learning environment. The growing number of virtual schools increases the need…

  11. X Python reference manual

    NARCIS (Netherlands)

    Mullender, K.S.

    1995-01-01

    This document describes the built-in types, exceptions, and functions of the X windows extension to Python. It assumes basic knowledge about the Python language and access to the X windows documentation. For an informal introduction to the language, see the Python Tutorial. The Python Reference Manu

  12. Extending reference assembly models

    DEFF Research Database (Denmark)

    Church, Deanna M.; Schneider, Valerie A.; Steinberg, Karyn Meltz;

    2015-01-01

    The human genome reference assembly is crucial for aligning and analyzing sequence data, and for genome annotation, among other roles. However, the models and analysis assumptions that underlie the current assembly need revising to fully represent human sequence diversity. Improved analysis tools...

  13. International Geomagnetic Reference Field

    DEFF Research Database (Denmark)

    Finlay, Chris; Maus, S.; Beggan, C. D.

    2010-01-01

    The eleventh generation of the International Geomagnetic Reference Field (IGRF) was adopted in December 2009 by the International Association of Geomagnetism and Aeronomy Working Group V‐MOD. It updates the previous IGRF generation with a definitive main field model for epoch 2005.0, a main field...

  14. Role and Reference Grammar.

    Science.gov (United States)

    Van Valin, Robert D., Jr.

    This paper discusses Role and Reference Grammar (RRG), which is a structuralist-formalist theory of grammar. RRG grew out of an attempt to answer two fundamental questions: (1) what would linguistic theory look like if it were based on the analysis of Lakhota, Tagalog, and Dyirbal, rather than on the analysis of English?; and (2) how can the…

  15. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted

  16. Digital Reference Service.

    Science.gov (United States)

    Mon, Lorri

    2000-01-01

    Discusses the increasing demand for digital reference services from government Web sites via email, and describes a partnership between the Government Printing Office and the federal depository library at the University of Illinois at Chicago to create electronic access to the Department of State Foreign Affairs Network (DOSFAN). (Author/LRW)

  17. An Amharic Reference Grammar.

    Science.gov (United States)

    Leslau, Wolf

    This reference grammar presents a structural description of the orthography, phonology, morphology, and syntax of Amharic, the national language of Ethiopia. The Amharic material in this work, designed to prepare the student for speaking and reading the language, appears in both Amharic script and phonetic transcription. See ED 012 044-5 for the…

  18. OSH technical reference manual

    Energy Technology Data Exchange (ETDEWEB)

    1993-11-01

    In an evaluation of the Department of Energy (DOE) Occupational Safety and Health programs for government-owned contractor-operated (GOCO) activities, the Department of Labor`s Occupational Safety and Health Administration (OSHA) recommended a technical information exchange program. The intent was to share written safety and health programs, plans, training manuals, and materials within the entire DOE community. The OSH Technical Reference (OTR) helps support the secretary`s response to the OSHA finding by providing a one-stop resource and referral for technical information that relates to safe operations and practice. It also serves as a technical information exchange tool to reference DOE-wide materials pertinent to specific safety topics and, with some modification, as a training aid. The OTR bridges the gap between general safety documents and very specific requirements documents. It is tailored to the DOE community and incorporates DOE field experience.

  19. Maritime Claims Reference Manual

    Science.gov (United States)

    1990-07-12

    8217 75028.8’ 28 Isla Conica 51010.7’ 75015.5’ 29 Roca Santa Lucia 51037.0’ 75.21.0’ 30 Roca Galicia 52003.4’ 75009.0’ 31 Islotes Evangelistas 52023.6’ 75005.6...amendment to the Marine Space Act which, inter alia , deletes reference to Rotuma as an archipelago. Instead, the waters within the baselines are

  20. Electrical engineer's reference book

    CERN Document Server

    Laughton, M A

    1985-01-01

    Electrical Engineer's Reference Book, Fourteenth Edition focuses on electrical engineering. The book first discusses units, mathematics, and physical quantities, including the international unit system, physical properties, and electricity. The text also looks at network and control systems analysis. The book examines materials used in electrical engineering. Topics include conducting materials, superconductors, silicon, insulating materials, electrical steels, and soft irons and relay steels. The text underscores electrical metrology and instrumentation, steam-generating plants, turbines

  1. GDB Pocket Reference

    CERN Document Server

    Robbins, Arnold

    2009-01-01

    The GNU debugger is valuable for testing, fixing, and retesting software because it allows you to see exactly what's going on inside of a program as it's executing. This new pocket reference shows you how to specify a target for debugging, perform a careful examination to find the cause of program failure, and make quick changes for further testing. The guide covers several popular programming languages.

  2. Open SHMEM Reference Implementation

    Energy Technology Data Exchange (ETDEWEB)

    2016-05-12

    OpenSHMEM is an effort to create a specification for a standardized API for parallel programming in the Partitioned Global Address Space. Along with the specification the project is also creating a reference implementation of the API. This implementation attempts to be portable, to allow it to be deployed in multiple environments, and to be a starting point for implementations targeted to particular hardware platforms. It will also serve as a springboard for future development of the API.

  3. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet age:

  4. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet

  5. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet

  6. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet age:

  7. Electroacoustical reference data

    CERN Document Server

    Eargle, John M

    2002-01-01

    The need for a general collection of electroacoustical reference and design data in graphical form has been felt by acousticians and engineers for some time. This type of data can otherwise only be found in a collection of handbooks. Therefore, it is the author's intention that this book serve as a single source for many electroacoustical reference and system design requirements. In form, the volume closely resembles Frank Massa's Acoustic Design Charts, a handy book dating from 1942 that has long been out of print. The basic format of Massa's book has been followed here: For each entry, graphical data are presented on the right page, while text, examples, and refer­ ences appear on the left page. In this manner, the user can solve a given problem without thumbing from one page to the next. All graphs and charts have been scaled for ease in data entry and reading. The book is divided into the following sections: A. General Acoustical Relationships. This section covers the behavior of sound transmis­ sion in...

  8. Applicability of the Hargraeves Method in Estimating Reference Evapotranspiration in the Taklamakan Desert Hinterland%Hargreaves公式在塔克拉玛干沙漠腹地的适用性

    Institute of Scientific and Technical Information of China (English)

    王永东; 李生宇; 徐新文; 雷加强; 金小军; 王强; 邸鲲; 张忠良

    2013-01-01

    对运用Hargreaves公式计算参考作物蒸散量(ET0)在干旱区的适用性存在不同观点.为了求证Hargreaves公式在极端干旱区塔克拉玛干沙漠腹地的适用性,利用2005-2010年塔克拉玛干沙漠研究站的气象资料,以利用Penman-Monteith公式计算的结果为标准,对利用Hargreaves公式计算的ET0进行了对比分析,并对两种计算结果差异的成因进行了阐释.结果表明:在年时间尺度上,利用Hargreaves公式计算的结果略大于利用Penman-Monteith公式计算的结果,标准差介于32.86~35.00 mm,年参考作物蒸散量计算结果呈现弱变异程度;在月时间尺度上,用两种方法计算的参考作物蒸散量呈现中等变异程度,蒸散量绝对偏差介于-3.26~8.73 mm,相对偏差介于-12.20%~29.02%,除了10月与11月,其余月份相对偏差均保持在10%之内.用两种方法计算的10月与11月份ET0产生差异的最主要原因在于有较高的温度较差.最后,经过对年、月参考作物蒸散量进行t-检验及建立回归方程,表明Hargreaves公式适用于极端干旱的塔克拉玛干沙漠腹地.%There are different opinions on the applicability of the Hargreaves method in calculating reference crop evapotranspiration (ET0) in arid land. In order to test the applicability of the Hargreaves method in the Taklamakan Desert hinterland, we carried out the current study using the metadata in 2005-2010 collected at the meteorological station in the Taklamakan Desert hinterland. The Penman-Monteith method was set as standard to compare the difference between the two methods. The results showed that at annual scale, the ET0 calculated with the Hargreaves equation was a little higher than that obtained by Penman-Monteith method, the standard deviation were 32. 86~35.00 mm, and the annual reference crop evapotranspiration (ET0) presented weak variation; at monthly scale, the reference crop evapotranspiration (ET0) presented a middle variation, the

  9. Reference blindness: the influence of references on trust in Wikipedia

    NARCIS (Netherlands)

    Lucassen, Teun; Noordzij, Matthijs L.; Schraagen, Jan Maarten

    2011-01-01

    In this study we show the influence of references on trust in information. We changed the contents of reference lists of Wikipedia articles in such a way that the new references were no longer in any sense related to the topic of the article. Furthermore, the length of the reference list was varied.

  10. 46 CFR 193.01-3 - Incorporation by reference.

    Science.gov (United States)

    2010-10-01

    ... PROTECTION EQUIPMENT Application § 193.01-3 Incorporation by reference. (a) Certain material is incorporated... Specification for International Shore Connections for Marine Fire Applications, incorporation by reference approved for § 193.10-10. (2) (c) National Fire Protection Association (NFPA), 1 Batterymarch Park,...

  11. Roaming Reference: Reinvigorating Reference through Point of Need Service

    Directory of Open Access Journals (Sweden)

    Kealin M. McCabe

    2011-11-01

    Full Text Available Roaming reference service was pursued as a way to address declining reference statistics. The service was staffed by librarians armed with iPads over a period of six months during the 2010-2011 academic year. Transactional statistics were collected in relation to query type (Research, Facilitative or Technology, location and approach (librarian to patron, patron to librarian or via chat widget. Overall, roaming reference resulted in an additional 228 reference questions, 67% (n=153 of which were research related. Two iterations of the service were implemented, roaming reference as a standalone service (Fall 2010 and roaming reference integrated with traditional reference desk duties (Winter 2011. The results demonstrate that although the Weller Library’s reference transactions are declining annually, they are not disappearing. For a roaming reference service to succeed, it must be a standalone service provided in addition to traditional reference services. The integration of the two reference models (roaming reference and reference desk resulted in a 56% decline in the total number of roaming reference questions from the previous term. The simple act of roaming has the potential to reinvigorate reference services as a whole, forcing librarians outside their comfort zones, allowing them to reach patrons at their point of need.

  12. Mechanical engineer's reference book

    CERN Document Server

    Parrish, A

    1973-01-01

    Mechanical Engineer's Reference Book: 11th Edition presents a comprehensive examination of the use of Systéme International d' Unités (SI) metrication. It discusses the effectiveness of such a system when used in the field of engineering. It addresses the basic concepts involved in thermodynamics and heat transfer. Some of the topics covered in the book are the metallurgy of iron and steel; screw threads and fasteners; hole basis and shaft basis fits; an introduction to geometrical tolerancing; mechanical working of steel; high strength alloy steels; advantages of making components as castings

  13. XSLT 10 Pocket Reference

    CERN Document Server

    Lenz, Evan

    2008-01-01

    XSLT is an essential tool for converting XML into other kinds of documents: HTML, PDF file, and many others. It's a critical technology for XML-based platforms such as Microsoft .NET, Sun Microsystems' Sun One, as well as for most web browsers and authoring tools. As useful as XSLT is, however, most people have a difficult time getting used to its peculiar characteristics. The ability to use advanced techniques depends on a clear and exact understanding of how XSLT templates work and interact. The XSLT 1.0 Pocket Reference from O'Reilly wants to make sure you achieve that level of understan

  14. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet age:A citation analysis of computer science literature.Information Processing and Manage-

  15. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet age:A citation analysis of computer science literature.Information Processing and Management,2001,37:661-675.2 Fernandez,M.,Kadiyska,Y.,&Suciu,D.,et al.SilkRoute:A framework for publishing

  16. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2008-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5th Ed.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet age:A citation analysis of computer science literature.Information Processing and Management,2001,37:661-675.

  17. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet age:A citation analysis of computer science literature.Information Processing and Management,2001,37:661-675.2 Fernandez.M

  18. Rails Pocket Reference

    CERN Document Server

    Berry, Eric

    2008-01-01

    Rails 2.1 brings a new level of stability and power to this acclaimed web development framework, but keeping track of its numerous moving parts is still a chore. Rails Pocket Reference offers you a painless alternative to hunting for resources online, with brief yet thorough explanations of the most frequently used methods and structures supported by Rails 2.1, along with key concepts you need to work through the framework's most tangled corners. Organized to help you quickly find what you need, this book will not only get you up to speed on how Rails works, it also provides a handy referenc

  19. Generic Crystalline Disposal Reference Case

    Energy Technology Data Exchange (ETDEWEB)

    Painter, Scott Leroy [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Chu, Shaoping [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Harp, Dylan Robert [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Perry, Frank Vinton [Los Alamos National Lab. (LANL), Los Alamos, NM (United States); Wang, Yifeng [Sandia National Lab. (SNL-NM), Albuquerque, NM (United States)

    2015-02-20

    A generic reference case for disposal of spent nuclear fuel and high-level radioactive waste in crystalline rock is outlined. The generic cases are intended to support development of disposal system modeling capability by establishing relevant baseline conditions and parameters. Establishment of a generic reference case requires that the emplacement concept, waste inventory, waste form, waste package, backfill/buffer properties, EBS failure scenarios, host rock properties, and biosphere be specified. The focus in this report is on those elements that are unique to crystalline disposal, especially the geosphere representation. Three emplacement concepts are suggested for further analyses: a waste packages containing 4 PWR assemblies emplaced in boreholes in the floors of tunnels (KBS-3 concept), a 12-assembly waste package emplaced in tunnels, and a 32-assembly dual purpose canister emplaced in tunnels. In addition, three failure scenarios were suggested for future use: a nominal scenario involving corrosion of the waste package in the tunnel emplacement concepts, a manufacturing defect scenario applicable to the KBS-3 concept, and a disruptive glaciation scenario applicable to both emplacement concepts. The computational approaches required to analyze EBS failure and transport processes in a crystalline rock repository are similar to those of argillite/shale, with the most significant difference being that the EBS in a crystalline rock repository will likely experience highly heterogeneous flow rates, which should be represented in the model. The computational approaches required to analyze radionuclide transport in the natural system are very different because of the highly channelized nature of fracture flow. Computational workflows tailored to crystalline rock based on discrete transport pathways extracted from discrete fracture network models are recommended.

  20. Sensor employing internal reference electrode

    DEFF Research Database (Denmark)

    2013-01-01

    The present invention concerns a novel internal reference electrode as well as a novel sensing electrode for an improved internal reference oxygen sensor and the sensor employing same.......The present invention concerns a novel internal reference electrode as well as a novel sensing electrode for an improved internal reference oxygen sensor and the sensor employing same....

  1. Coal data: A reference

    Energy Technology Data Exchange (ETDEWEB)

    1995-02-01

    This report, Coal Data: A Reference, summarizes basic information on the mining and use of coal, an important source of energy in the US. This report is written for a general audience. The goal is to cover basic material and strike a reasonable compromise between overly generalized statements and detailed analyses. The section ``Supplemental Figures and Tables`` contains statistics, graphs, maps, and other illustrations that show trends, patterns, geographic locations, and similar coal-related information. The section ``Coal Terminology and Related Information`` provides additional information about terms mentioned in the text and introduces some new terms. The last edition of Coal Data: A Reference was published in 1991. The present edition contains updated data as well as expanded reviews and additional information. Added to the text are discussions of coal quality, coal prices, unions, and strikes. The appendix has been expanded to provide statistics on a variety of additional topics, such as: trends in coal production and royalties from Federal and Indian coal leases, hours worked and earnings for coal mine employment, railroad coal shipments and revenues, waterborne coal traffic, coal export loading terminals, utility coal combustion byproducts, and trace elements in coal. The information in this report has been gleaned mainly from the sources in the bibliography. The reader interested in going beyond the scope of this report should consult these sources. The statistics are largely from reports published by the Energy Information Administration.

  2. The OTIS Reference Manual

    CERN Document Server

    Deppe, H; Trunk, U; Uwer, U

    2008-01-01

    This document describes the port definitions, electrical specifications, modes of operation and programming sequences of the OTIS TDC. The chip is developed for the Outer Tracker of the LHCb experiment. OTIS1.0 is the first full-scale prototype of this 32 channel TDC and has been submitted in April 2002 in a standard 0.25µm CMOS process. Within the clock driven architecture of the chip a DLL provides the reference for the drift time measurement. The drift time data of every channel is stored in the pipeline memory until a trigger decision arrives. A control unit provides memory and trigger management and handles data transmission to the subsequent DAQ stage. The latest chip version is OTIS1.3.

  3. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2009-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet age:A citation analysis of computer science literature.Information Processing and Management,2001,37:661-675.2 Fernandez,M.,Kadiyska,Y.,&Suciu,D.,et al.SilkRoute:A framework for publishing relational data in XML.ACM Transactions on Database Systems,2002,27(4):438-493.

  4. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2010-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet age:A citation analysis of computer science literature.Information Processing and Management,2001,37:661-675.2 Fernandez,M.,Kadiyska,Y.,&Suciu,D.,et al.SilkRoute:A framework for publishing relational data in XML.ACM Transactions on Database Systems,2002,27(4):438-493.

  5. Reference Citation Format

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    <正>The format for citations in text and for bibliographic references follows the Publication Manual of the American Psychological Association(5thEd.,2001)and GB/T 7714-2005.The citation of printed word should be ordered in number as it appears in the text of the submitted article.For journal article1 Goodrum,A.A.,McCain,K.W.,&Lawrence,S.,et al.Scholarly publishing in the Internet age:A citation analysis of computer science literature.Information Processing and Management,2001,37:661-675.2 Fernandez,M.,Kadiyska,Y.,&Suciu,D.,et al.SilkRoute:A framework for publishing relational data in XML.ACM Transactions on Database Systems,2002,27(4):438-493.

  6. Tank characterization reference guide

    Energy Technology Data Exchange (ETDEWEB)

    De Lorenzo, D.S.; DiCenso, A.T.; Hiller, D.B.; Johnson, K.W.; Rutherford, J.H.; Smith, D.J. [Los Alamos Technical Associates, Kennewick, WA (United States); Simpson, B.C. [Westinghouse Hanford Co., Richland, WA (United States)

    1994-09-01

    Characterization of the Hanford Site high-level waste storage tanks supports safety issue resolution; operations and maintenance requirements; and retrieval, pretreatment, vitrification, and disposal technology development. Technical, historical, and programmatic information about the waste tanks is often scattered among many sources, if it is documented at all. This Tank Characterization Reference Guide, therefore, serves as a common location for much of the generic tank information that is otherwise contained in many documents. The report is intended to be an introduction to the issues and history surrounding the generation, storage, and management of the liquid process wastes, and a presentation of the sampling, analysis, and modeling activities that support the current waste characterization. This report should provide a basis upon which those unfamiliar with the Hanford Site tank farms can start their research.

  7. Areva reference document 2007; Areva document de reference 2007

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2008-07-01

    This reference document contains information on the AREVA group's objectives, prospects and development strategies, particularly in Chapters 4 and 7. It contains also information on the markets, market shares and competitive position of the AREVA group. Content: 1 - Person responsible for the reference document and persons responsible for auditing the financial statements; 2 - Information pertaining to the transaction (not applicable); 3 - General information on the company and its share capital: Information on Areva, Information on share capital and voting rights, Investment certificate trading, Dividends, Organization chart of AREVA group companies, Equity interests, Shareholders' agreements; 4 - Information on company operations, new developments and future prospects: Overview and strategy of the AREVA group, The Nuclear Power and Transmission and Distribution markets, The energy businesses of the AREVA group, Front End division, Reactors and Services division, Back End division, Transmission and Distribution division, Major contracts 140 Principal sites of the AREVA group, AREVA's customers and suppliers, Sustainable Development and Continuous Improvement, Capital spending programs, Research and Development programs, Intellectual Property and Trademarks, Risk and insurance; 5 - Assets financial position financial performance: Analysis of and comments on the group's financial position and performance, Human Resources report, Environmental report, Consolidated financial statements 2007, Notes to the consolidated financial statements, Annual financial statements 2007, Notes to the corporate financial statements; 6 - Corporate governance: Composition and functioning of corporate bodies, Executive compensation, Profit-sharing plans, AREVA Values Charter, Annual Ordinary General Meeting of Shareholders of April 17, 2008; 7 - Recent developments and future prospects: Events subsequent to year-end closing for 2007, Outlook; Glossary; table of

  8. Areva, reference document 2006; Areva, document de reference 2006

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2006-07-01

    This reference document contains information on the AREVA group's objectives, prospects and development strategies, particularly in Chapters 4 and 7. It contains information on the markets, market shares and competitive position of the AREVA group. Content: - 1 Person responsible for the reference document and persons responsible for auditing the financial statements; - 2 Information pertaining to the transaction (Not applicable); - 3 General information on the company and its share capital: Information on AREVA, on share capital and voting rights, Investment certificate trading, Dividends, Organization chart of AREVA group companies, Equity interests, Shareholders' agreements; - 4 Information on company operations, new developments and future prospects: Overview and strategy of the AREVA group, The Nuclear Power and Transmission and Distribution markets, The energy businesses of the AREVA group, Front End division, Reactors and Services division, Back End division, Transmission and Distribution division, Major contracts, The principal sites of the AREVA group, AREVA's customers and suppliers, Sustainable Development and Continuous Improvement, Capital spending programs, Research and development programs, intellectual property and trademarks, Risk and insurance; - 5 Assets - Financial position - Financial performance: Analysis of and comments on the group's financial position and performance, 2006 Human Resources Report, Environmental Report, Consolidated financial statements, Notes to the consolidated financial statements, AREVA SA financial statements, Notes to the corporate financial statements; 6 - Corporate Governance: Composition and functioning of corporate bodies, Executive compensation, Profit-sharing plans, AREVA Values Charter, Annual Combined General Meeting of Shareholders of May 3, 2007; 7 - Recent developments and future prospects: Events subsequent to year-end closing for 2006, Outlook; 8 - Glossary; 9 - Table of concordance.

  9. Preliminary reference Earth model

    Science.gov (United States)

    Dziewonski, Adam M.; Anderson, Don L.

    1981-06-01

    A large data set consisting of about 1000 normal mode periods, 500 summary travel time observations, 100 normal mode Q values, mass and moment of inertia have been inverted to obtain the radial distribution of elastic properties, Q values and density in the Earth's interior. The data set was supplemented with a special study of 12 years of ISC phase data which yielded an additional 1.75 × 10 6 travel time observations for P and S waves. In order to obtain satisfactory agreement with the entire data set we were required to take into account anelastic dispersion. The introduction of transverse isotropy into the outer 220 km of the mantle was required in order to satisfy the shorter period fundamental toroidal and spheroidal modes. This anisotropy also improved the fit of the larger data set. The horizontal and vertical velocities in the upper mantle differ by 2-4%, both for P and S waves. The mantle below 220 km is not required to be anisotropic. Mantle Rayleigh waves are surprisingly sensitive to compressional velocity in the upper mantle. High S n velocities, low P n velocities and a pronounced low-velocity zone are features of most global inversion models that are suppressed when anisotropy is allowed for in the inversion. The Preliminary Reference Earth Model, PREM, and auxiliary tables showing fits to the data are presented.

  10. Reference change values.

    Science.gov (United States)

    Fraser, Callum G

    2011-09-30

    Reference change values (RCV) provide objective tools for assessment of the significance of differences in serial results from an individual. The concept is simple and the calculation easy, since all laboratories know their analytical imprecision (CV(A)) and estimates of within-subject biological variation (CV(I)) are available for a large number of quantities. Generally, CV(I) are constant over time, geography, methodology and in health and chronic stable disease. The formula is RCV=2(1/2) · Z · (CV(A)(2) + CV(I)(2))(1/2), where Z is the number of standard deviations appropriate to the probability. Correct interpretation of the semantics describing the clinical use of RCV is vital for selection of the Z-score. Many quantities of clinically importance exist for which good estimates of RCV are unavailable. Derivation of CV(I) may be difficult for such quantities: flair and imagination are required in selecting populations with chronic but stable disease on whom CV(I) can be determined. RCV can be used for delta-checking and auto-verification and laboratory information management systems (LIMS) can be adapted to do this. Recently, log-normal transformation to obtain unidirectional RCV has been used. Gaps in knowledge of RCV still require filling since the need for measures of change is clearly expressed in guidelines.

  11. Sensor Characteristics Reference Guide

    Energy Technology Data Exchange (ETDEWEB)

    Cree, Johnathan V.; Dansu, A.; Fuhr, P.; Lanzisera, Steven M.; McIntyre, T.; Muehleisen, Ralph T.; Starke, M.; Banerjee, Pranab; Kuruganti, T.; Castello, C.

    2013-04-01

    The Buildings Technologies Office (BTO), within the U.S. Department of Energy (DOE), Office of Energy Efficiency and Renewable Energy (EERE), is initiating a new program in Sensor and Controls. The vision of this program is: • Buildings operating automatically and continuously at peak energy efficiency over their lifetimes and interoperating effectively with the electric power grid. • Buildings that are self-configuring, self-commissioning, self-learning, self-diagnosing, self-healing, and self-transacting to enable continuous peak performance. • Lower overall building operating costs and higher asset valuation. The overarching goal is to capture 30% energy savings by enhanced management of energy consuming assets and systems through development of cost-effective sensors and controls. One step in achieving this vision is the publication of this Sensor Characteristics Reference Guide. The purpose of the guide is to inform building owners and operators of the current status, capabilities, and limitations of sensor technologies. It is hoped that this guide will aid in the design and procurement process and result in successful implementation of building sensor and control systems. DOE will also use this guide to identify research priorities, develop future specifications for potential market adoption, and provide market clarity through unbiased information

  12. The Herschel Reference Survey

    CERN Document Server

    Boselli, A; Cortese, L; Bendo, G; Chanial, P; Buat, V; Davies, J; Auld, R; Rigby, E; Baes, M; Barlow, M; Bock, J; Bradford, M; Castro-Rodriguez, N; Charlot, S; Clements, D; Cormier, D; Dwek, E; Elbaz, D; Galametz, M; Galliano, F; Gear, W; Glenn, J; Gomez, H; Griffin, M; Hony, S; Isaak, K; Levenson, L; Lu, N; Madden, S; O'Halloran, B; Okumura, K; Oliver, S; Page, M; Panuzzo, P; Papageorgiou, A; Parkin, T; Perez-Fournon, I; Pohlen, M; Rangwala, N; Roussel, H; Rykala, A; Sacchi, N; Sauvage, M; Schulz, B; Schirm, M; Smith, M W L; Spinoglio, L; Stevens, J; Symeonidis, M; Vaccari, M; Vigroux, L; Wilson, C; Wozniak, H; Wright, G; Zeilinger, W

    2010-01-01

    The Herschel Reference Survey is a guaranteed time Herschel key project and will be a benchmark study of dust in the nearby universe. The survey will complement a number of other Herschel key projects including large cosmological surveys that trace dust in the distant universe. We will use Herschel to produce images of a statistically-complete sample of 323 galaxies at 250, 350 and 500 micron. The sample is volume-limited, containing sources with distances between 15 and 25 Mpc and flux limits in the K-band to minimize the selection effects associated with dust and with young high-mass stars and to introduce a selection in stellar mass. The sample spans the whole range of morphological types (ellipticals to late-type spirals) and environments (from the field to the centre of the Virgo Cluster) and as such will be useful for other purposes than our own. We plan to use the survey to investigate (i) the dust content of galaxies as a function of Hubble type, stellar mass and environment, (ii) the connection betwe...

  13. Global Reference Tables Services Architecture

    Data.gov (United States)

    Social Security Administration — This database stores the reference and transactional data used to provide a data-driven service access method to certain Global Reference Table (GRT) service tables.

  14. Using machine learning to produce near surface soil moisture estimates from deeper in situ records at U.S. Climate Reference Network (USCRN) locations: Analysis and applications to AMSR-E satellite validation

    Science.gov (United States)

    Coopersmith, Evan J.; Cosh, Michael H.; Bell, Jesse E.; Boyles, Ryan

    2016-12-01

    Surface soil moisture is a critical parameter for understanding the energy flux at the land atmosphere boundary. Weather modeling, climate prediction, and remote sensing validation are some of the applications for surface soil moisture information. The most common in situ measurement for these purposes are sensors that are installed at depths of approximately 5 cm. There are however, sensor technologies and network designs that do not provide an estimate at this depth. If soil moisture estimates at deeper depths could be extrapolated to the near surface, in situ networks providing estimates at other depths would see their values enhanced. Soil moisture sensors from the U.S. Climate Reference Network (USCRN) were used to generate models of 5 cm soil moisture, with 10 cm soil moisture measurements and antecedent precipitation as inputs, via machine learning techniques. Validation was conducted with the available, in situ, 5 cm resources. It was shown that a 5 cm estimate, which was extrapolated from a 10 cm sensor and antecedent local precipitation, produced a root-mean-squared-error (RMSE) of 0.0215 m3/m3. Next, these machine-learning-generated 5 cm estimates were also compared to AMSR-E estimates at these locations. These results were then compared with the performance of the actual in situ readings against the AMSR-E data. The machine learning estimates at 5 cm produced an RMSE of approximately 0.03 m3/m3 when an optimized gain and offset were applied. This is necessary considering the performance of AMSR-E in locations characterized by high vegetation water contents, which are present across North Carolina. Lastly, the application of this extrapolation technique is applied to the ECONet in North Carolina, which provides a 10 cm depth measurement as its shallowest soil moisture estimate. A raw RMSE of 0.028 m3/m3 was achieved, and with a linear gain and offset applied at each ECONet site, an RMSE of 0.013 m3/m3 was possible.

  15. Global daily reference evapotranspiration modeling and evaluation

    Science.gov (United States)

    Senay, G.B.; Verdin, J.P.; Lietzow, R.; Melesse, Assefa M.

    2008-01-01

    Accurate and reliable evapotranspiration (ET) datasets are crucial in regional water and energy balance studies. Due to the complex instrumentation requirements, actual ET values are generally estimated from reference ET values by adjustment factors using coefficients for water stress and vegetation conditions, commonly referred to as crop coefficients. Until recently, the modeling of reference ET has been solely based on important weather variables collected from weather stations that are generally located in selected agro-climatic locations. Since 2001, the National Oceanic and Atmospheric Administration's Global Data Assimilation System (GDAS) has been producing six-hourly climate parameter datasets that are used to calculate daily reference ET for the whole globe at 1-degree spatial resolution. The U.S. Geological Survey Center for Earth Resources Observation and Science has been producing daily reference ET (ETo) since 2001, and it has been used on a variety of operational hydrological models for drought and streamflow monitoring all over the world. With the increasing availability of local station-based reference ET estimates, we evaluated the GDAS-based reference ET estimates using data from the California Irrigation Management Information System (CIMIS). Daily CIMIS reference ET estimates from 85 stations were compared with GDAS-based reference ET at different spatial and temporal scales using five-year daily data from 2002 through 2006. Despite the large difference in spatial scale (point vs. ???100 km grid cell) between the two datasets, the correlations between station-based ET and GDAS-ET were very high, exceeding 0.97 on a daily basis to more than 0.99 on time scales of more than 10 days. Both the temporal and spatial correspondences in trend/pattern and magnitudes between the two datasets were satisfactory, suggesting the reliability of using GDAS parameter-based reference ET for regional water and energy balance studies in many parts of the world

  16. Jakarta Struts Pocket Reference

    CERN Document Server

    Cavaness, Chuck

    2003-01-01

    Web tier frameworks have soared in popularity over the past year or so due to the increasing complexity of Java itself, and the need to get more work done with fewer resources. Developers who used to spend hours and hours writing low-level features can use a well-written framework to build the presentation tier so they start coding the "good stuff" sooner--the business logic at the core of the program. The Jakarta Struts Framework is one of the most popular presentation frameworks for building web applications with Java Servlet and JavaServer Pages (JSP) technologies. If you work with the St

  17. Fundamentals of Managing Reference Collections

    Science.gov (United States)

    Singer, Carol A.

    2012-01-01

    Whether a library's reference collection is large or small, it needs constant attention. Singer's book offers information and insight on best practices for reference collection management, no matter the size, and shows why managing without a plan is a recipe for clutter and confusion. In this very practical guide, reference librarians will learn:…

  18. A reference model for database security proxy

    Institute of Scientific and Technical Information of China (English)

    2002-01-01

    How to protect the database, the kernel resources of information warfare, is becoming more and more important since the rapid development of computer and communication technology. As an application-level firewall, database security proxy can successfully repulse attacks originated from outside the network, reduce to zerolevel damage from foreign DBMS products. We enhanced the capability of the COAST's firewall reference model by adding a transmission unit modification function and an attribute value mapping function, describes the schematic and semantic layer reference model, and finally forms a reference model for DBMS security proxy which greatly helps in the design and implementation of database security proxies. This modeling process can clearly separate the system functionality into three layers, define the possible security functions for each layer, and estimate the computational cost for each layer.

  19. A reference model for database security proxy

    Institute of Scientific and Technical Information of China (English)

    蔡亮; 杨小虎; 董金祥

    2002-01-01

    How to protect the database, the kernel resources of information warfare, is becoming more and more important since the rapid development of computer and communication technology. As an application-level firewall, database security proxy can successfully repulse attacks originated from outside the network, reduce to zerolevel damage from foreign DBMS products. We enhanced the capability of the COAST' s firewall reference model by adding a transmission unit modification function and an attribute value mapping function,describes the schematic and semantic layer reference model, and finally forms a reference model for DBMS security proxy which greatly helps in the design and implementation of database security proxies. This modeling process can clearly separate the system functionality into three layers, define the possible security functions for each layer, and estimate the computational cost for each layer.

  20. Co-reference and reasoning.

    Science.gov (United States)

    Walsh, Clare R; Johnson-Laird, P N

    2004-01-01

    Co-reference occurs when two or more noun phrases refer to the same individual, as in the following inferential problem: Mark is kneeling by the fire or he is looking at the TV but not both. / Mark is kneeling by the fire. / Is he looking at the TV? In three experiments, we compared co-referential reasoning problems with problems referring to different individuals. Experiment 1 showed that co-reference improves accuracy. In Experiment 2, we replicated that finding and showed that co-reference speeds up both reading and inference. Experiment 3 showed that the effects of co-reference are greatest when the premises and the conclusion share co-referents. These effects led the participants to make illusory inferences--that is, to draw systematically invalid conclusions. The results are discussed in terms of the mental model theory of reasoning.

  1. Reference models supporting enterprise networks and virtual enterprises

    DEFF Research Database (Denmark)

    Tølle, Martin; Bernus, Peter

    2003-01-01

    This article analyses different types of reference models applicable to support the set up and (re)configuration of Virtual Enterprises (VEs). Reference models are models capturing concepts common to VEs aiming to convert the task of setting up of VE into a configuration task, and hence reducing ...... the time needed for VE creation. The reference models are analysed through a mapping onto the Virtual Enterprise Reference Architecture (VERA) based upon GERAM and created in the IMS GLOBEMEN project.......This article analyses different types of reference models applicable to support the set up and (re)configuration of Virtual Enterprises (VEs). Reference models are models capturing concepts common to VEs aiming to convert the task of setting up of VE into a configuration task, and hence reducing...

  2. The effect of reference choices on the spatio-temporal analysis of brain evoked potentials: the use of infinite reference.

    Science.gov (United States)

    Yao, Dezhong; Wang, Li; Arendt-Nielsen, Lars; Chen, Andrew C N

    2007-11-01

    Reference is a very virtual issue in EEG and ERP. Understanding the difference of various references will make the applications more confident. In this work, somatosensory evoked potential (SEP) with stimulation on the right hand was studied. The SEP spatio-temporal analysis was conducted comparatively on six references, left mastoid (contralateral mastoid reference, CM), right mastoid (ipsilateral mastoid reference, IM), linked mastoids (LM), average reference (AR), vertex reference (Cz) and the infinity reference (IR) newly proposed in 2001. Among the six, CM is the one used in actual recordings, and the other five are obtained by off-line re-referencing. The comparison is conducted on four selected components (P30 ms, P40 ms, N90 ms and P230 ms) in both temporal and spatial aspects. The results show that references may have a distinct influence on the amplitudes of the scalp potentials, with relative error at some electrodes larger than 500%, and for some electrodes it may even change the polarity. Pair-wise multiple comparison (Tukey test) shows that the differences of peak values among various references are very significant (P or =LM>IR>AR>Cz. The two-ways (the six references vs. the four Peaks) repeated measures ANOVA test shows the effect of different references depends on various components; there is a statistically significant interaction between reference and the peak (P=future.

  3. An Internet of Things Generic Reference Architecture

    DEFF Research Database (Denmark)

    Bhalerao, Dipashree M.; Riaz, Tahir; Madsen, Ole Brun

    2013-01-01

    Internet of things Network is a future application of Internet. This network has three major basic blocks as business process or Application, core network or internetwork and peripheral network as Things or objects. The assembly has the basic intention of connecting all physical and virtual things......, and keeping track of all these things for monitoring and controlling some information. IoT architecture is studied from software architecture, overall system architecture and network architecture point of view. Paper puts forward the requirements of software architecture along with, its component...... and deployment diagram, process and interface diagram at abstract level. Paper proposes the abstract generic IoT reference and concrete abstract generic IoT reference architectures. Network architecture is also put up as a state of the art. Paper shortly gives overviews of protocols used for IoT. Some...

  4. Interchangeable spline reference guide

    Energy Technology Data Exchange (ETDEWEB)

    Dolin, R.M.

    1994-05-01

    The WX-Division Integrated Software Tools (WIST) Team evolved from two previous committees, First was the W78 Solid Modeling Pilot Project`s Spline Subcommittee, which later evolved into the Vv`X-Division Spline Committee. The mission of the WIST team is to investigate current CAE engineering processes relating to complex geometry and to develop methods for improving those processes. Specifically, the WIST team is developing technology that allows the Division to use multiple spline representations. We are also updating the contour system (CONSYS) data base to take full advantage of the Division`s expanding electronic engineering process. Both of these efforts involve developing interfaces to commercial CAE systems and writing new software. The WIST team is comprised of members from V;X-11, -12 and 13. This {open_quotes}cross-functional{close_quotes} approach to software development is somewhat new in the Division so an effort is being made to formalize our processes and assure quality at each phase of development. Chapter one represents a theory manual and is one phase of the formal process. The theory manual is followed by a software requirements document, specification document, software verification and validation documents. The purpose of this guide is to present the theory underlying the interchangeable spline technology and application. Verification and validation test results are also presented for proof of principal.

  5. Virtual Reference Interferometry: Theory & Experiment

    Science.gov (United States)

    Galle, Michael Anthony

    This thesis introduces the idea that a simulated interferogram can be used as a reference for an interferometer. This new concept represents a paradigm shift from the conventional thinking, where a reference is the phase of a wavefront that traverses a known path. The simulated interferogram used as a reference is called a virtual reference. This thesis develops the theory of virtual reference interferometry and uses it for the characterization of chromatic dispersion in short length (virtual reference combines the advantages of these techniques so that it is both accurate and easy to operate. Chromatic dispersion measurements based on virtual reference interferometry have similar accuracy as the best conventional measurement techniques due to the ability to measure first and second order dispersion directly from the interference pattern. Unique capabilities of virtual reference interferometry are demonstrated, followed by a derivation of the operational constraints and system parameters. The technique is also applied to the characterization of few-mode fibers, a hot topic in telecommunications research where mode division multiplexing promises to expand network bandwidth. Also introduced is the theory of dispersive virtual reference interferometry, which can be used to overcome the bandwidth limitations associated with the measurement of near-zero dispersion-length optical components via compression of the interference pattern. Additionally, a method for utilizing the virtual reference interferometer in a low-coherence setup is introduced, enabling characterization in new wavelength ranges and further reducing the cost of characterization.

  6. Validation of reference transcripts in strawberry (Fragaria spp.).

    Science.gov (United States)

    Clancy, Maureen A; Rosli, Hernan G; Chamala, Srikar; Barbazuk, W Brad; Civello, P Marcos; Folta, Kevin M

    2013-12-01

    Contemporary methods to assay gene expression depend on a stable set of reference transcripts for accurate quantitation. A lack of well-tested reference genes slows progress in characterizing gene expression in high-value specialty crops. In this study, a set of strawberry (Fragaria spp.) constitutively expressed reference genes has been identified by merging digital gene expression data with expression profiling. Constitutive reference candidates were validated using quantitative PCR and hybridization. Several transcripts have been identified that show improved stability across tissues relative to traditional reference transcripts. Results are similar between commercial octoploid strawberry and the diploid model. Our findings also show that while some never-before-used references are appropriate for most applications, even the most stable reference transcripts require careful assessment across the diverse tissues and fruit developmental states before being adopted as controls.

  7. 参考作物蒸散简易估算方法在黄土高原的适用性%Applicability of simple estimating method for reference crop evapotranspiration in Loess Plateau

    Institute of Scientific and Technical Information of China (English)

    李志

    2012-01-01

    Some methods for estimating reference crop evapotranspiration (ETo) are widely used in regions with insufficient meteorological data, but their applicabilities should be evaluated. The performances of six simple methods for estimating ET0 (i.e. FAO-24 Rad, FAO-24 BC, Hargreaves, Priestley-Taylor, Makkink and Turc) are evaluated based on the meteorological data from 48 stations during 1961 -2009 in the Loess Plateau. Results showed that FAO-24 BC and Hargreaves equations were satisfactory to estimate annual ETo while Makkink and Priestley-Taylor methods are not. The estimation errors of annual ETo mainly come from those in November to March, while in April to October were very small. Spatial variability exist in the applicability of the six methods. FAO-24 BC and Hargreaves performs better at most stations while the other methods, especially for Makkink and Priestley-Taylor, provide unsatisfactory results. Most methods are not suitable for estimating ETo in the southwest region except for Priestley-Taylor. Overall, FAO-24 BC and Hargreaves are recommended as the priority simple methods for calculating ETo in the Loess Plateau.%参考作物蒸散(ET0)的简易估算方法在气象数据缺乏区域具有广泛的应用,但其适用性需要评估.基于1961~2009年48个气象站的数据,以FAO Penman-Monteith公式为标准评估了6种ET0简易估算方法(FAO-24 Rad、FAO-24 BC、Hargreaves、Priestley-Taylor、Makkink和Turc)在黄土高原应用的可能性.结果表明,对于ET0年值的估算,FAO-24 BC和Hargreaves的结果令人满意,效果最差的是Makkink和Priestley-Taylor公式.ET0年值误差主要来源于11-3月,各方法对4-10月ET0的估算效果相对较好.各方法的适用性存在空间变异,FAO-24 BC和Hargreaves公式的效果普遍较好,其他方法对该区各站ET0估算误差均较大,特别是Makkink和Priestley-Taylor公式;除Priestley-Taylor公式外,多数方法对西南区的估算误差较大.因此,黄土

  8. Relativistic formulation and reference frame

    OpenAIRE

    Klioner, Sergei A.

    2004-01-01

    After a short review of experimental foundations of metric theories of gravity, the choice of general relativity as a theory to be used for the routine modeling of Gaia observations is justified. General principles of relativistic modeling of astronomical observations are then sketched and compared to the corresponding Newtonian principles. The fundamental reference system -- Barycentric Celestial Reference System, which has been chosen to be the relativistic reference system underlying the f...

  9. User Preferences in Reference Services: Virtual Reference and Academic Libraries

    Science.gov (United States)

    Cummings, Joel; Cummings, Lara; Frederiksen, Linda

    2007-01-01

    This study examines the use of chat in an academic library's user population and where virtual reference services might fit within the spectrum of public services offered by academic libraries. Using questionnaires, this research demonstrates that many within the academic community are open to the idea of chat-based reference or using chat for…

  10. Acute Myeloid Leukemia - Genetics Home Reference [Genetics Home Reference (Conditions)

    Lifescience Database Archive (English)

    Full Text Available Conditions Genes Chromosomes Handbook Glossary Resources Conditions > Acute Myeloid...te myeloid leukemia with mutated CEBPA Fanconi anemia You may also search Genetics Home Reference for Acut...e Myeloid Leukemia for additional information. Published : October 27, 2014 Acute Myeloid Leukemia - Genetics Home Reference ...

  11. Java for dummies quick reference

    CERN Document Server

    Lowe, Doug

    2012-01-01

    A reference that answers your questions as you move through your coding The demand for Android programming and web apps continues to grow at an unprecedented pace and Java is the preferred language for both. Java For Dummies Quick Reference keeps you moving through your coding while you solve a problem, look up a command or syntax, or search for a programming tip. Whether you're a Java newbie or a seasoned user, this fast reference offers you quick access to solutions without requiring that you wade through pages of tutorial material. Leverages the true reference format that is organized with

  12. Public-key cryptography based on bounded quantum reference frames

    OpenAIRE

    Ioannou, Lawrence M.; Mosca, Michele

    2009-01-01

    We demonstrate that the framework of bounded quantum reference frames has application to building quantum-public-key cryptographic protocols and proving their security. Thus, the framework we introduce can be seen as a public-key analogue of the framework of Bartlett et al. (Phys. Rev. A 70, 032307), where a private shared reference frame is shown to have cryptographic application. The protocol we present in this paper is an identification scheme, which, like a digital signature scheme, is a ...

  13. Dedicated online virtual reference instruction.

    Science.gov (United States)

    Guillot, Ladonna; Stahr, Beth; Plaisance, Louise

    2005-01-01

    To facilitate nursing students' information literacy skills and enhance traditional library user services, academic librarians have developed synchronous (real-time) online virtual reference instruction in nursing research classes. The authors discuss collaborative efforts of nursing and library faculty in planning, implementing, and evaluating a discipline-specific virtual reference pilot program.

  14. The Virtual Reference Librarian's Handbook.

    Science.gov (United States)

    Lipow, Anne Grodzins

    This book is a practical guide to librarians and their administrators who are thinking about or in the early stages of providing virtual reference service. Part 1, "The Decision to Go Virtual," provides a context for thinking about virtual reference, including the benefits and problems, getting in the virtual frame of mind, and shopping…

  15. Reference counting for reversible languages

    DEFF Research Database (Denmark)

    Mogensen, Torben Ægidius

    2014-01-01

    deallocation. This requires the language to be linear: A pointer can not be copied and it can only be eliminated by deallocating the node to which it points. We overcome this limitation by adding reference counts to nodes: Copying a pointer to a node increases the reference count of the node and eliminating...

  16. Technostress and the Reference Librarian.

    Science.gov (United States)

    Kupersmith, John

    1992-01-01

    Defines "technostress" as the stress experienced by reference librarians who must constantly deal with the demands of new information technology and the changes they produce in the work place. Discussion includes suggested ways in which both organizations and individuals can work to reduce stress. (27 references) (LAE)

  17. Reference analysis of the signal + background model in counting experiments II. Approximate reference prior

    Science.gov (United States)

    Casadei, D.

    2014-10-01

    The objective Bayesian treatment of a model representing two independent Poisson processes, labelled as ``signal'' and ``background'' and both contributing additively to the total number of counted events, is considered. It is shown that the reference prior for the parameter of interest (the signal intensity) can be well approximated by the widely (ab)used flat prior only when the expected background is very high. On the other hand, a very simple approximation (the limiting form of the reference prior for perfect prior background knowledge) can be safely used over a large portion of the background parameters space. The resulting approximate reference posterior is a Gamma density whose parameters are related to the observed counts. This limiting form is simpler than the result obtained with a flat prior, with the additional advantage of representing a much closer approximation to the reference posterior in all cases. Hence such limiting prior should be considered a better default or conventional prior than the uniform prior. On the computing side, it is shown that a 2-parameter fitting function is able to reproduce extremely well the reference prior for any background prior. Thus, it can be useful in applications requiring the evaluation of the reference prior for a very large number of times.

  18. Reference image selection for difference imaging analysis

    CERN Document Server

    Huckvale, Leo; Sale, Stuart E

    2014-01-01

    Difference image analysis (DIA) is an effective technique for obtaining photometry in crowded fields, relative to a chosen reference image. As yet, however, optimal reference image selection is an unsolved problem. We examine how this selection depends on the combination of seeing, background and detector pixel size. Our tests use a combination of simulated data and quality indicators from DIA of well-sampled optical data and under-sampled near-infrared data from the OGLE and VVV surveys, respectively. We search for a figure-of-merit (FoM) which could be used to select reference images for each survey. While we do not find a universally applicable FoM, survey-specific measures indicate that the effect of spatial under-sampling may require a change in strategy from the standard DIA approach, even though seeing remains the primary criterion. We find that background is not an important criterion for reference selection, at least for the dynamic range in the images we test. For our analysis of VVV data in particu...

  19. Linking English-Language Test Scores onto the Common European Framework of Reference: An Application of Standard-Setting Methodology. TOEFL iBT Research Report TOEFL iBt-06. ETS RR-08-34

    Science.gov (United States)

    Tannenbaum, Richard J.; Wylie, E. Caroline

    2008-01-01

    The Common European Framework of Reference (CEFR) describes language proficiency in reading, writing, speaking, and listening on a 6-level scale. In this study, English-language experts from across Europe linked CEFR levels to scores on three tests: the TOEFL® iBT test, the TOEIC® assessment, and the TOEIC "Bridge"™ test.…

  20. Avaliação da ingestão de nutrientes de crianças de uma creche filantrópica: aplicação do Consumo Dietético de Referência Assessment of nutrients intake of children in a charity daycare center: application of Dietary Reference Intake

    Directory of Open Access Journals (Sweden)

    Roseane Moreira Sampaio Barbosa

    2007-04-01

    Full Text Available OBJETIVOS: comparar a adequação aparente da ingestão dos nutrientes utilizando os valores de referência "Consumo Dietético de Referência" (Dietary Reference Intake-DRIs de 35 crianças de uma creche filantrópica, em dois momentos, no ato da matrícula (momento 1 e após seis meses de freqüência na creche (momento 2. MÉTODOS: A avaliação sócio-demográfica foi realizada através de questionário abordando renda, escolaridade, condições de moradia e saneamento básico. Para avaliação do consumo alimentar, no ato da matrícula, a história dietética foi determinada em entrevista com o responsável, com o propósito de obter informações sobre consumo habitual da criança na sua residência. Após o período de seis meses foi utilizado o método de pesagem direta de alimentos (na creche complementando com o consumo alimentar da criança na residência. A análise dos nutrientes como proteínas, ferro, cálcio e vitamina C, além das fibras alimentares, foi realizada através um programa computacional. Para comparar a adequação dos nutrientes nos dois momentos do estudo utilizou-se o teste t de Student para dados pareados (p OBJECTIVES: to compare nutrients intake apparent adequacy through reference values of Dietary Reference Intake (DRIs of 35 children of a charity daycare center in two instances, when they enrolled (instance 1 and six months after (instance 2. METHODS: socio-demographic assessment was performed through a questionnaire collecting information pertaining to income, school level, living conditions and basic sanitation. To assess food consumption at enrollment, dietary history was informed through an interview with the parent, family member or guardian on the usual intake of the child at home. Following a six month period the weighed food record method (in the daycare center was performed complemented by the food intake of the child at home. Nutrient analysis such as proteins, iron, calcium and vitamin C in

  1. The Preliminaries of a Reference

    DEFF Research Database (Denmark)

    Butler, Graham; Sadl, Urska

    2017-01-01

    by the reasons why the Court after an oral hearing held in the presence of the parties and eight intervening Member States, and after hearing the Advocate General did not deliver one. The comment examines the legal framework, as well as the detailed procedural rules and guidelines that govern the cooperation...... of national courts in the preliminary reference procedure. It highlights the fact that preliminary references can only work when the preliminaries of a reference – the culture of sincere cooperation and litigation, efficient communication and flexible procedural rules – are in place....

  2. Improved scatterometry time-to-solution using virtual reference

    Science.gov (United States)

    Vaid, Alok; Iddawela, Givantha; Tsai, Jamie; Wainreb, Gilad; Isbester, Paul; Kang, Byung Cheol (Charles); Klots, Michael; Katz, Yinon; Bozdog, Cornel; Sendelbach, Matt

    2015-03-01

    Advanced nodes require precise detection and control of intricate profile details - scatterometry is tool of choice for such requirements. Scatterometry is a model-based technique, and needs extensive reference metrology for qualification. Such reference measurements are costly, time-consuming and often destructive causing delays in deployment. With increasing number of scatterometry steps in flow, and the requirement to collect more reference data points to statistically qualify shrinking metrology specifications, the cost and time for reference metrology is exponentially increasing. This work is aimed to significantly reduce this need. We developed a novel methodology whereby scatterometry spectral information itself is used to predict "virtual" reference data. We qualify this methodology on several key applications from 20nm and 14nm node. We find that performance of solution developed using proposed methodology is indeed similar to performance of solution obtained using real reference data, thereby significantly reducing the lead time to develop scatterometry solutions.

  3. Phase measurement profilometry based on a virtual reference plane method

    Science.gov (United States)

    Ren, Hongbing; Lee, Jinlong; Gao, Xiaorong

    2016-09-01

    In Phase Measurement Profilometry(PMP), the setting of the reference plane plays an important role. It is a critical step to capture the grating fringe projected onto the reference plane in PMP. However, it is sometimes difficult to choose and place the reference plane in practical applications. In this paper, a virtual reference plane is introduced into PMP, with which 3D measurement can be realized without using the physical reference plane. The virtual reference plane is generated through extracting a partial area of the deformed fringe image that corresponds to a planar region and employing the interpolation algorithm. The method is proved theoretically through simulation experiments, providing a new suggestion for actual measurement by PMP.

  4. The validation of housekeeping genes as a reference in quantitative Real Time PCR analysis: application in the milk somatic cells and frozen whole blood of goats infected with caprine arthritis encephalitis virus.

    Science.gov (United States)

    Jarczak, Justyna; Kaba, Jarosław; Bagnicka, Emilia

    2014-10-10

    The validation of housekeeping genes (HKGs) for normalization of RNA expression in Real-Time PCR is crucial to obtain the most reliable results. There is limited information on reference genes used in the study of gene expression in milk somatic cells and the frozen whole blood of goats. Thus, the aim of this study was to propose the most stable housekeeping genes that can be used as a reference in Real-Time PCR analysis of milk somatic cells and whole blood of goats infected with caprine arthritis encephalitis virus (CAEV). Animals were divided into two groups: non-infected (N=13) and infected with CAEV (N=13). Biological material (milk somatic cells and whole blood) was collected 4 times during the lactation period (7, 30, 100 and 240days post-partum). The expression levels of candidate reference genes were analyzed using geNorm and NormFinder software. The stability of candidates for reference gene expression was analyzed for CAEV-free (control) and CAEV-infected groups, and also for both groups together (combined group). The stability of expression of β-actin (ACTB), glyceraldehyde-3P-dehydrogenase (GAPDH), cyclophilin A (PPIA), RNA18S1, ubiquilin (UBQLN1) and ribosomal protein large subunit P0 (RPLP0) was determined in milk somatic cells, while ACTB, PPIA, RPLP0, succinate dehydrogenase complex subunit A (SDHA), zeta polypeptide (YWHAZ), battenin (CLN3), eukaryotic translation initiation factor 3K (EIF3K) and TATA box-binding protein (TBP) were measured in frozen whole blood of goats. PPIA and RPLP0 were considered as the most suitable internal controls as they were stably expressed in milk somatic cells regardless of disease status, according to NormFinder software. Furthermore, geNorm results indicated the expression of PPIA/RPLP0 genes as the best combination under these experimental conditions. The results of frozen whole blood analysis using NormFinder software revealed that the most stable reference gene in control, CAEV-infected and combined groups is

  5. Calibration of Priestley-Taylor and Hargreaves and its applicability for both alfalfa and grass reference crops%Priestley-Taylor和Hargreaves公式在高矮两种参考作物上的适应性与率定

    Institute of Scientific and Technical Information of China (English)

    吕玉平; 徐俊增; 李斌; 孙璐; 杨士红

    2015-01-01

    以ASCE标准Penman-Montieth公式为基准,在不同气候区分别对Priestley-Taylor和Hargreaves这两种常用的参考作物蒸发蒸腾量EFref计算公式在高矮两种参考作物上进行适应性分析、地区率定以及率定公式验证。结果表明:以矮型参考作物为参考面时, Priestley-Taylor和Hargreaves公式分别在湿润区和干旱区具有较好的适应性,但对于EFref的估算仍具有较大的误差,两公式均不能直接应用于高型参考作物;经地区率定后两公式在干旱、半干旱半湿润、湿润3个气候区高型参考作物上的计算精度显著改善,但仍低于在矮型参考作物上的精度,Priestley-Taylor公式在气候区间的差异性不明显,Hargreaves公式在干旱区有更好的适应性。%With ASCE standardized reference Penman-Montieth as benchmark reference evapotranspiration equation, two commonly used ETref estimating methods, namely Priestley-Taylor and Hargreaves, were evaluated, local calibrated and validated in different climate regions in China. The results showed that Priestley-Taylor and Hargreaves performed better for grass reference crop in humid and arid regions,respectively. But the error in ETref estimating is unneglectable, and its can not be applied directly to alfalfa reference crop without local calibration. The local calibrated Priestley-Taylor and Hargreaves performed better in different climate regions, and the accuracy was significantly improved for alfalfa reference crop. Both methods performed better on grass than alfalfa reference crop. Performance of Priestley-Taylor showed no significant difference in different climate region, and Hargreaves had higher precision in arid region.

  6. Genetics Home Reference: warfarin resistance

    Science.gov (United States)

    ... novel VKORC1 mutations associated with oral anticoagulant resistance: insights into improved patient diagnosis and treatment. J Thromb ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  7. Genetics Home Reference: Canavan disease

    Science.gov (United States)

    ... disease, a rare early-onset human spongiform leukodystrophy: insights into its genesis and possible clinical interventions. Biochimie. ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  8. Genetics Home Reference: Vohwinkel syndrome

    Science.gov (United States)

    ... of connexins in ear and skin physiology - functional insights from disease-associated mutations. Biochim Biophys Acta. 2013 ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  9. Genetics Home Reference: Larsen syndrome

    Science.gov (United States)

    ... affinity in the absence of major structural disturbance: Insights from the crystal structures of filamin B actin ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  10. Genetics Home Reference: Brugada syndrome

    Science.gov (United States)

    ... rare variation in arrhythmia-susceptibility genes provides new insights into molecular diagnosis for Brugada syndrome. Hum Mol ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  11. Genetics Home Reference: psoriatic arthritis

    Science.gov (United States)

    ... PubMed Nograles KE, Brasington RD, Bowcock AM. New insights into the pathogenesis and genetics of psoriatic arthritis. ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  12. Genetics Home Reference: boomerang dysplasia

    Science.gov (United States)

    ... affinity in the absence of major structural disturbance: Insights from the crystal structures of filamin B actin ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  13. Genetics Home Reference: Meckel syndrome

    Science.gov (United States)

    ... genetics and pathogenic mechanisms for the severe ciliopathies: insights into neurodevelopment and pathogenesis of neural tube defects. ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  14. Genetics Home Reference: Brody myopathy

    Science.gov (United States)

    ... Kuppevelt TH, Ferlini A, Tomelleri G. Brody disease: insights into biochemical features of SERCA1 and identification of ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  15. Genetics Home Reference: hidradenitis suppurativa

    Science.gov (United States)

    ... JN. γ-Secretase mutations in hidradenitis suppurativa: new insights into disease pathogenesis. J Invest Dermatol. 2013 Mar; ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  16. Genetics Home Reference: Wolfram syndrome

    Science.gov (United States)

    ... V. Genotypic classification of patients with Wolfram syndrome: insights into the natural history of the disease and ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  17. Crescent Lake Wilderness Reference Sheet

    Data.gov (United States)

    US Fish and Wildlife Service, Department of the Interior — Reference sheet includes information about Crescent Lake National Wildlife Refuge, and results of the public hearing for Crescent Lake Wilderness Proposal.

  18. World Reference Center for Arboviruses.

    Science.gov (United States)

    1985-01-01

    viruses from many parts of the world. 7 %, 1.1%vl ’ e- "., Distribution of reagents. The reference center distributed 970 ampoules of reference sera...eight pools of Culiseta melanura collected during 1984 as part of a field study on Lyme disease and other zoonoses in Connecticut. A ninth strain was...dense amorphous masses, were present also in the cytoplasm. Smooth-surfaced reticula occurred in the cytoplasm and contained viral particles in

  19. Virtual reference: chat with us!

    Science.gov (United States)

    Lapidus, Mariana; Bond, Irena

    2009-01-01

    Virtual chat services represent an exciting way to provide patrons of medical libraries with instant reference help in an academic environment. The purpose of this article is to examine the implementation, marketing process, use, and development of a virtual reference service initiated at the Massachusetts College of Pharmacy and Health Sciences and its three-campus libraries. In addition, this paper will discuss practical recommendations for the future improvement of the service.

  20. TclTk Pocket Reference

    CERN Document Server

    Raines, Paul

    1998-01-01

    The Tcl/Tk combination is increasingly popular because it lets you produce sophisticated graphical interfaces with a few easy commands, develop and change scripts quickly, and conveniently tie together existing utilities or programming libraries. The Tcl/Tk Pocket Reference,a handy reference guide to the basic Tcl language elements, Tcl and Tk commands, and Tk widgets, is a companion volume to Tcl/Tk in a Nutshell.

  1. Nonorthogonal orbital based n-body reduced density matrices and their applications to valence bond theory. III. Second-order perturbation theory using valence bond self-consistent field function as reference.

    Science.gov (United States)

    Chen, Zhenhua; Chen, Xun; Ying, Fuming; Gu, Junjing; Zhang, Huaiyu; Wu, Wei

    2014-10-07

    Using the formulas and techniques developed in Papers I and II of this series, the recently developed second-order perturbation theory based on a valence bond self-consistent field reference function (VBPT2) has been extended by using the internally contracted correction wave function. This ansatz strongly reduces the size of the interaction space compared to the uncontracted wave function and thus improves the capability of the VBPT2 method dramatically. Test calculations show that internally contracted VBPT2 using only a small number of reference valence bond functions, can give results as accuracy as the VBPT2 method and other more sophisticated methods such as full configuration interaction and multireference configuration interaction.

  2. Research on the Application of IM and SNS in University Library’s Virtual Reference Service%IM与SNS在高校图书馆虚拟参考咨询服务中的应用研究

    Institute of Scientific and Technical Information of China (English)

    张鹏; 梁玉磊

    2014-01-01

    阐述了高校图书馆虚拟参考咨询服务所用工具IM与SNS的特点,对高校图书馆虚拟参考咨询服务所用的2种IM工具和5种SNS工具进行了比较,提出了高校图书馆移动服务的解决策略。%This paper expounds the features of IM(instant messaging) and SNS(social networking services), the tools used in university library’s virtual reference services, compares two IM tools and five SNS tools used in university library’s virtual reference services, and puts forward some solutions for university library’s mobile services.

  3. Referring Expressions: A Unified Approach

    Institute of Scientific and Technical Information of China (English)

    K.M. Jaszczolt

    2001-01-01

    @@ 0. Introduction Expressions used by speakers to refer are commonly divided into two categories: that of directly referring expressions and that of expressions whose referring function is secured by the context of utterance. Directly referring expressions are normally said to include proper names, some pronouns including demonstrative, and demonstrative phrases. The other category comprises mainly definite and indefinite descriptions, the first being their most acclaimed representative. Definite descriptions are widely acknowledged to have referential uses. They are not referring expressions, so to speak, by default,but rather as a result of a contextually determined interpretation. As a category, they are frequently said to belong with quantifiers (Neale 1990; Recanati 1993). However, the arguments for classifying them with referring expressions are ample (Bach 1987a; Larson & Segal 1995; Brown 1995; Jaszczolt 1997a,1997b, 1999b). It is argued in Part I of this paper that although definite descriptions exhibit an ambiguity of use between the referential and the attributive reading, they also exhibit the property of having an unmarked, salient interpretation which makes them akin to directly referential terms. This salient reading is the referential interpretation, arrived at with the help of the hearer′s presumption of the presence of strong referential intention that supports the speaker′s utterance.

  4. Korean Reference HLW Disposal System

    Energy Technology Data Exchange (ETDEWEB)

    Choi, Heui Joo; Lee, J. Y.; Kim, S. S. (and others)

    2008-03-15

    This report outlines the results related to the development of Korean Reference Disposal System for High-level radioactive wastes. The research has been supported around for 10 years through a long-term research plan by MOST. The reference disposal method was selected via the first stage of the research during which the technical guidelines for the geological disposal of HLW were determined too. At the second stage of the research, the conceptual design of the reference disposal system was made. For this purpose the characteristics of the reference spent fuels from PWR and CANDU reactors were specified, and the material and specifications of the canisters were determined in term of structural analysis and manufacturing capability in Korea. Also, the mechanical and chemical characteristics of the domestic Ca-bentonite were analyzed in order to supply the basic design parameters of the buffer. Based on these parameters the thermal and mechanical analysis of the near-field was carried out. Thermal-Hydraulic-Mechanical behavior of the disposal system was analyzed. The reference disposal system was proposed through the second year research. At the final third stage of the research, the Korean Reference disposal System including the engineered barrier, surface facilities, and underground facilities was proposed through the performance analysis of the disposal system.

  5. Using Virtual Reference Transcripts for Staff Training.

    Science.gov (United States)

    Ward, David

    2003-01-01

    Describes a method of library staff training based on chat transcript analysis in which graduate student workers at a university reference desk examined transcripts of actual virtual reference desk transactions to analyze reference interviews. Discusses reference interview standards, reference desk behavior, and reference interview skills in…

  6. Calibration of {sup 90}Sr+{sup 90}Y chemical applicators using a mini extrapolation chamber as reference system;Calibracao de aplicadores clinicos de {sup 90}Sr+{sup 90}Y utilizando uma mini-camera de extrapolacao como sistema de referencia

    Energy Technology Data Exchange (ETDEWEB)

    Antonio, Patricia L.; Caldas, Linda V.E. [Instituto de Pesquisas Energeticas e Nucleares (IPEN/CNEN-SP), Sao Paulo, SP (Brazil); Oliveira, Mercia L. [Centro Regional de Ciencias Nucleares do Nordeste (CRCN-NE/CNEN-PE), Recife, PE (Brazil)

    2009-07-01

    {sup 90}Sr + {sup 90}Y clinical applicators are beta radiation sources utilized in several radiotherapy Brazilian clinics, although don't be more manufactured. These sources are employed in brachytherapy procedures for the treatment of superficial lesions of skin and eyes. International recommendations and previous works determine that dermatological and ophthalmic applicators shall be calibrated periodically, and one of the methods for their calibration consists of the use of an extrapolation chamber. In this work, a method of calibration of {sup 90}Sr + {sup 90}Y clinical applicators was applied using a mini-extrapolation chamber of plane window, developed at the Calibration Laboratory at IPEN, as a reference system. The results obtained were considered satisfactory, when compared with the results given in the calibration certificates of the sources. (author)

  7. Reference Anytime Anywhere: Towards Virtual Reference Services at Penn State.

    Science.gov (United States)

    Moyo, Lesley M.

    2002-01-01

    Outlines the service rationale, software and technology considerations taken by the Pennsylvania State University library in planning towards online, real-time reference services and provides an overview of the planned pilot project. Discusses recent trends in academic electronic libraries, including providing value-added services to support…

  8. Virtual Reference, Real Money: Modeling Costs in Virtual Reference Services

    Science.gov (United States)

    Eakin, Lori; Pomerantz, Jeffrey

    2009-01-01

    Libraries nationwide are in yet another phase of belt tightening. Without an understanding of the economic factors that influence library operations, however, controlling costs and performing cost-benefit analyses on services is difficult. This paper describes a project to develop a cost model for collaborative virtual reference services. This…

  9. Reference Anywhere, Anytime: Recent Works on Virtual Reference

    Science.gov (United States)

    Lindsay, Elizabeth Blakesley

    2008-01-01

    The topic of virtual reference has been a popular one in the past year, and this column highlights a range of those articles. Included are overviews of the topic, articles addressing specific technological solutions and concerns, and pieces that explore the intricacies of delivering and assessing a "traditional" service through a…

  10. Acute - Glossary Entry - Genetics Home Reference [Genetics Home Reference (Glossary)

    Lifescience Database Archive (English)

    Full Text Available | F | G | H | I | J | K | L | M | N | O | P | Q-R | S | T | U | V | W | X | Y-Z Acute Definition(s) Having ...ding Medical Terminology . Published : October 27, 2014 Acute - Glossary Entry - Genetics Home Reference ...

  11. Swahili Learners' Reference Grammar. African Language Learners' Reference Grammar Series.

    Science.gov (United States)

    Thompson, Katrina Daly; Schleicher, Antonia Folarin

    This reference grammar is written for speakers of English who are learning Swahili. Because many language learners are not familiar with the grammatical terminology, this book explains the basic terminology and concepts of English grammar that are necessary for understanding the grammar of Swahili. It assumes no formal knowledge of English grammar…

  12. Fast Reference-Based MRI

    CERN Document Server

    Weizman, Lior; Ben-Basaht, Dafna

    2015-01-01

    In many clinical MRI scenarios, existing imaging information can be used to significantly shorten acquisition time or to improve Signal to Noise Ratio (SNR). In some cases, a previously acquired image can serve as a reference image, that may exhibit similarity to the image being acquired. Examples include similarity between adjacent slices in high resolution MRI, similarity between various contrasts in the same scan and similarity between different scans of the same patient. In this paper we present a general framework for utilizing reference images for fast MRI. We take into account that the reference image may exhibit low similarity with the acquired image and develop an iterative weighted approach for reconstruction, which tunes the weights according to the degree of similarity. Experiments demonstrate the performance of the method in three different clinical MRI scenarios: SNR improvement in high resolution brain MRI, utilizing similarity between T2-weighted and fluid-attenuated inversion recovery (FLAIR)...

  13. Haemostatic reference intervals in pregnancy

    DEFF Research Database (Denmark)

    Szecsi, Pal Bela; Jørgensen, Maja; Klajnbard, Anna;

    2010-01-01

    Haemostatic reference intervals are generally based on samples from non-pregnant women. Thus, they may not be relevant to pregnant women, a problem that may hinder accurate diagnosis and treatment of haemostatic disorders during pregnancy. In this study, we establish gestational age......-specific reference intervals for coagulation tests during normal pregnancy. Eight hundred one women with expected normal pregnancies were included in the study. Of these women, 391 had no complications during pregnancy, vaginal delivery, or postpartum period. Plasma samples were obtained at gestational weeks 13......-20, 21-28, 29-34, 35-42, at active labor, and on postpartum days 1 and 2. Reference intervals for each gestational period using only the uncomplicated pregnancies were calculated in all 391 women for activated partial thromboplastin time (aPTT), fibrinogen, fibrin D-dimer, antithrombin, free protein S...

  14. JavaScript programmer's reference

    CERN Document Server

    Valentine, Thomas

    2013-01-01

    JavaScript Programmer's Reference is an invaluable resource that won't stray far from your desktop (or your tablet!). It contains detailed information on every JavaScript object and command, and combines that reference with practical examples showcasing how you can use those commands in the real world. Whether you're just checking the syntax of a method or you're starting out on the road to JavaScript mastery, the JavaScript Programmer's Reference will be an essential aid.  With a detailed and informative tutorial section giving you the ins and outs of programming with JavaScript and the DOM f

  15. The Rosia Language Reference Manual

    Science.gov (United States)

    1981-12-01

    Alternate database 16 Anaphora 26, 30, 56 Anaphoric reference 30 Arithmetic expressions 33 Arithmetic operators 8 Bind 54 Binding 54, 57 BNF 94...Descriptions as Class Membership Tests .......... 28 4.2.7. Descriptions and Modification ................... 29 4.2.8. Anaphoric Descriptions...54 4.9.3. Variable Binding ................................ 54 4.9.4. Pattern Matching ................................ 55 5

  16. Tractor Transmissions. A Teaching Reference.

    Science.gov (United States)

    American Association for Agricultural Engineering and Vocational Agriculture, Athens, GA.

    The manual was developed as a reference for teaching students about transmissions in farm tractors. The manual is divided into five sections: (1) transmission history, (2) gears and bearings in transmission, (3) sliding-gear transmissions, (4) planetary gearing, and (5) glossary. The working principles of the sliding-gear transmission, the most…

  17. Genetics Home Reference: Pyle disease

    Science.gov (United States)

    ... Superti-Furga A, Baron R. Cortical-Bone Fragility--Insights from sFRP4 Deficiency in Pyle's Disease. N Engl ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  18. Genetics Home Reference: atopic dermatitis

    Science.gov (United States)

    ... 0b013e32830e6fb2. Review. Citation on PubMed Shaker M. New insights into the allergic march. Curr Opin Pediatr. 2014 ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  19. Haemostatic reference intervals in pregnancy

    DEFF Research Database (Denmark)

    Szecsi, Pal Bela; Jørgensen, Maja; Klajnbard, Anna;

    2010-01-01

    Haemostatic reference intervals are generally based on samples from non-pregnant women. Thus, they may not be relevant to pregnant women, a problem that may hinder accurate diagnosis and treatment of haemostatic disorders during pregnancy. In this study, we establish gestational age-specific refe......Haemostatic reference intervals are generally based on samples from non-pregnant women. Thus, they may not be relevant to pregnant women, a problem that may hinder accurate diagnosis and treatment of haemostatic disorders during pregnancy. In this study, we establish gestational age......-specific reference intervals for coagulation tests during normal pregnancy. Eight hundred one women with expected normal pregnancies were included in the study. Of these women, 391 had no complications during pregnancy, vaginal delivery, or postpartum period. Plasma samples were obtained at gestational weeks 13......-20, 21-28, 29-34, 35-42, at active labor, and on postpartum days 1 and 2. Reference intervals for each gestational period using only the uncomplicated pregnancies were calculated in all 391 women for activated partial thromboplastin time (aPTT), fibrinogen, fibrin D-dimer, antithrombin, free protein S...

  20. Space-Time Reference Systems

    CERN Document Server

    Soffel, Michael

    2013-01-01

    The high accuracy of modern astronomical spatial-temporal reference systems has made them considerably complex. This book offers a comprehensive overview of such systems. It begins with a discussion of ‘The Problem of Time’, including recent developments in the art of clock making (e.g., optical clocks) and various time scales. The authors address  the definitions and realization of spatial coordinates by reference to remote celestial objects such as quasars. After an extensive treatment of classical equinox-based coordinates, new paradigms for setting up a celestial reference system are introduced that no longer refer to the translational and rotational motion of the Earth. The role of relativity in the definition and realization of such systems is clarified. The topics presented in this book are complemented by exercises (with solutions). The authors offer a series of files, written in Maple, a standard computer algebra system, to help readers get a feel for the various models and orders of magnitude. ...

  1. Guam and Micronesia Reference Sources.

    Science.gov (United States)

    Goetzfridt, Nicholas J.; Goniwiecha, Mark C.

    1993-01-01

    This article lists reference sources for studying Guam and Micronesia. The entries are arranged alphabetically by main entry within each section in the categories of: (1) bibliographical works; (2) travel and guide books; (3) handbooks and surveys; (4) dictionaries; (5) yearbooks; (6) periodical and newspaper publications; and (7) audiovisual…

  2. A Computerized Reference Retrieval System.

    Science.gov (United States)

    Harline, N. La Var

    An automated retrieval system for reference works was constructed as a prototype in order to illustrate the capabilities and potentialities of future retrieval systems. More than 170 biographical works were indexed and stored in a computer disk to form a biographical data base, and a computer program was written to match patron queries. Consistent…

  3. [Developmental Placement.] Collected Research References.

    Science.gov (United States)

    Bjorklund, Gail

    Drawing on information and references in the ERIC system, this literature review describes research related to a child's developmental placement. The issues examined include school entrance age; predictive validity, reliability, and features of Gesell School Readiness Assessment; retention; and the effectiveness of developmental placement. A…

  4. Childhood Obesity. Special Reference Briefs.

    Science.gov (United States)

    Winick, Myron

    This reference brief deals with the problem of childhood obesity and how it can lead to obesity in the adult. Eighty-four abstracts are presented of studies on the identification, prevention, and treatment of obesity in children, focusing on diet and psychological attitudes. Subjects of the studies were children ranging in age from infancy through…

  5. Selected Reference Books of 1998.

    Science.gov (United States)

    McIlvaine, Eileen

    1999-01-01

    Reviews a selection of recent scholarly and general reference works under the categories of Periodicals and Newspapers, Philosophy, Literature, Film and Radio, Art and Architecture, Music, Political Science, Women's Studies, and History. A brief summary of new editions of standard works is provided at the end of the articles. (AEF)

  6. Selected Reference Books of 1992.

    Science.gov (United States)

    McIlvaine, Eileen

    1993-01-01

    Presents an annotated bibliography of 40 recent scholarly and general works of interest to reference workers in university libraries. Topics areas covered include philosophy, religion, language, literature, architecture, economics, law, area studies, Russia and the Soviet Union, women's studies, and Christopher Columbus. New editions and…

  7. Reference Values of Skin Autofluorescence

    NARCIS (Netherlands)

    Koetsier, M.; Lutgers, H. L.; de Jonge, C.; Links, T. P.; Smit, A. J.; Graaff, R.

    2010-01-01

    Background: Skin autofluorescence (AF) as measured with the AGE Reader (DiagnOptics Technologies, Groningen, The Netherlands) is a noninvasive prognostic marker in diabetes mellitus and other diseases with increased cardiovascular risk. This study provides reference values of healthy Caucasian contr

  8. Mobile Technologies and Roving Reference

    Science.gov (United States)

    Penner, Katherine

    2011-01-01

    As 21st century librarians, we have made apt adjustments for reaching out into the digital world, but we need to consider the students who still use library services within our walls. We can use available handheld, mobile technologies to help patrons too shy to approach the desk and free library staff to bring reference service directly to patrons.

  9. Development of a dual-internal-reference technique to improve accuracy when determining bacterial 16S rRNA:16S rRNA gene ratio with application to Escherichia coli liquid and aerosol samples.

    Science.gov (United States)

    Zhen, Huajun; Krumins, Valdis; Fennell, Donna E; Mainelis, Gediminas

    2015-10-01

    Accurate enumeration of rRNA content in microbial cells, e.g. by using the 16S rRNA:16S rRNA gene ratio, is critical to properly understand its relationship to microbial activities. However, few studies have considered possible methodological artifacts that may contribute to the variability of rRNA analysis results. In this study, a technique utilizing genomic DNA and 16S rRNA from an exogenous species (Pseudomonas fluorescens) as dual internal references was developed to improve accuracy when determining the 16S rRNA:16S rRNA gene ratio of a target organism, Escherichia coli. This technique was able to adequately control the variability in sample processing and analysis procedures due to nucleic acid (DNA and RNA) losses, inefficient reverse transcription of RNA, and inefficient PCR amplification. The measured 16S rRNA:16S rRNA gene ratio of E. coli increased by 2-3 fold when E. coli 16S rRNA gene and 16S rRNA quantities were normalized to the sample-specific fractional recoveries of reference (P. fluorescens) 16S rRNA gene and 16S rRNA, respectively. In addition, the intra-sample variation of this ratio, represented by coefficients of variation from replicate samples, decreased significantly after normalization. This technique was applied to investigate the temporal variation of 16S rRNA:16S rRNA gene ratio of E. coli during its non-steady-state growth in a complex liquid medium, and to E. coli aerosols when exposed to particle-free air after their collection on a filter. The 16S rRNA:16S rRNA gene ratio of E. coli increased significantly during its early exponential phase of growth; when E. coli aerosols were exposed to extended filtration stress after sample collection, the ratio also increased. In contrast, no significant temporal trend in E. coli 16S rRNA:16S rRNA gene ratio was observed when the determined ratios were not normalized based on the recoveries of dual references. The developed technique could be widely applied in studies of relationship between

  10. Canvas Pocket Reference Scripted Graphics for HTML5

    CERN Document Server

    Flanagan, David

    2010-01-01

    The Canvas element is a revolutionary feature of HTML5 that enables powerful graphics for rich Internet applications, and this pocket reference provides the essentials you need to put this element to work. If you have working knowledge of JavaScript, this book will help you create detailed, interactive, and animated graphics -- from charts to animations to video games -- whether you're a web designer or a programmer interested in graphics. Canvas Pocket Reference provides both a tutorial that covers all of the element's features with plenty of examples and a definitive reference to each of t

  11. OpenGIS参考模型ORM及地理信息服务应用模式%OpenGIS Reference Model(ORM)and Application Schema for Geographic Information Services

    Institute of Scientific and Technical Information of China (English)

    于海龙; 邬伦

    2004-01-01

    地理信息语义互操作是地理信息共享应用的基础,为解决OpenGIS抽象规范与实施规范在地理信息语义描述上的不足,OGC建立了OpenGIS参考模型(OpenGIS Reference Model,ORM),旨在通过ORM实现地理信息共享与互操作.该文从空间信息应用政策、空间信息语义描述、空间信息服务定义与分类、多网络服务配置、共享开发标准五个层面介绍ORM,并分析基于ORM的地理信息服务应用模式.

  12. Application of reference method in the standardization for the determination of alanine aminotransferase%参考方法在丙氨酸氨基转移酶测定标准化中的应用

    Institute of Scientific and Technical Information of China (English)

    郑松柏; 王建兵; 黄宪章; 马艳; 庄俊华; 徐宁; 周华友; 陈茶

    2012-01-01

    Objective To investigate the accuracy and comparability of alanine aminotransferase(ALT) measurement results in human serum samples and commercial materials before and after calibration with frozen human serum calibrator assigned by reference method. Methods Five frozen human-pooled serum samples were assigned values by the reference method without pyridoxal 5-phosphate for ALT in four candidate reference laboratories, which were used to evaluate the results of ALT catalytic activity detected by ten testing systems in Guangzhou. One of the serum sample was used as the common calibrator. The results of serum samples and commercial materials from different systems before and after calibration were analyzed for biases and intersystem variations. Results After calibration,the variance of the systems for the results of serum samples decreased from between 11. 90% and 8. 60% to between 6. 78% and 2. 30% ,and the bias decreased dramatically from between - 12. 52% and - 8. 44 % to between - 3. 36% and -0. 08%. Slopes of the regression lines of ALT results of serum samples between reference systems and routine systems after calibration were closer to 1 and intercepts closer to 0 than those obtained before calibration. Conclusion Accuracy and comparability of ALT measurements could be improved by using a common human serum calibrator. But commercial materials might not be commutable for human serum in ALT measurements.%目的 调查不同检测系统使用经参考方法赋值的冰冻人血清样本作为校准品进行校准后,不同来源样本丙氨酸氨基转移酶(ALT)测定结果的可比性与准确性的改变程度.方法 5份经4家候选参考实验室应用不含磷酸吡哆醛的ALT参考方法定值的冰冻人混合血清样本用于评价广州地区10个不同检测系统ALT催化活性结果的可比性与准确性.其中一个样本用作校准品校准各系统.比较校准前后各系统间新鲜血清样本与商品制备物测定

  13. Crowdsourcing Application of Virtual Reference Service in University Libraries%众包在高校图书馆虚拟参考咨询服务中的运用

    Institute of Scientific and Technical Information of China (English)

    薛红

    2012-01-01

    The paper introduced crowdsourcing and its advantages. Human resource shortage is one of the bottlenecks for the development of virtual reference service in university libraries, crowdsourcing model will contribute to further enhancing its service level and service quality.%众包借助互联网的优势,低成本汇聚各地的人力资源,解决原本需要高昂费用才能解决甚至不能解决的问题。人力资源不足是影响高校虚拟参考咨询服务健康发展的瓶颈之一,学习、借鉴和引进众包模式,将有助于进一步提高其服务水平和服务质量。

  14. Application of Health Belief Model\\'s constructs for predicting regular consumption of folic acid supplements in pregnant women referred to Borazjan’s health centers in 2014-15

    Directory of Open Access Journals (Sweden)

    Zohre kafaee

    2016-04-01

    Full Text Available Background: One of the most common disorders in pregnancy is Folic Acid deficiency and its complications. The aim of this study was to examine the predictors of regular use of folic acid supplements based on HBM in pregnant women referred to Borazjan’s health centers. Material and Methods: In this cross-sectional study, 228 pregnant women or women with planning of pregnancy referred to health centers of Borazjan with random sampling method evaluated. Data was collected with questionnaire in 4 parts included demographic characteristics, knowledge, health belief model constructs and questions about folic acid supplement use. Data was analyzed by SPSS software with using appropriate statistical tests. Results: The mean age of samples was 27.4±5.41. 144 patients (63.2% consumed Folic Acid pills regularly, and 84 patients (36.8% had irregular use. The awareness of folic acid in 22.8% of women was good, 59.6%  and 17.5% of samples had intermediate and poor awareness, respectively. The perceived barriers (P<0.001, perceived benefits (P=0.002 and self-efficacy (P<0.001 had relation with consumption of folic acid and among demographic variables, only education level (P=0.04 had relation with the consumption of pills. In logistic regression perceived barriers was only predictor. Age and educational level had indirect effect in regular consume pill. Conclusion: Perceived barriers was strongest predictors of folic acid use, therefore intervention based on health belief model, with emphasis on reducing barriers is necessary for improving the use of this medicine during pregnancy.

  15. Mixed quantum/classical theory for inelastic scattering of asymmetric-top-rotor + atom in the body-fixed reference frame and application to the H{sub 2}O + He system

    Energy Technology Data Exchange (ETDEWEB)

    Semenov, Alexander [Chemistry Department, Wehr Chemistry Building, Marquette University, Milwaukee, Wisconsin 53201-1881 (United States); PSL Research University, Observatoire de Paris, Sorbonne Universités, UPMC Univ Paris 06, ENS, UCP, CNRS, UMR8112, LERMA, 5 Place Janssen, 92195 Meudon (France); Dubernet, Marie-Lise [PSL Research University, Observatoire de Paris, Sorbonne Universités, UPMC Univ Paris 06, ENS, UCP, CNRS, UMR8112, LERMA, 5 Place Janssen, 92195 Meudon (France); Babikov, Dmitri, E-mail: dmitri.babikov@mu.edu [Chemistry Department, Wehr Chemistry Building, Marquette University, Milwaukee, Wisconsin 53201-1881 (United States)

    2014-09-21

    The mixed quantum/classical theory (MQCT) for inelastic molecule-atom scattering developed recently [A. Semenov and D. Babikov, J. Chem. Phys. 139, 174108 (2013)] is extended to treat a general case of an asymmetric-top-rotor molecule in the body-fixed reference frame. This complements a similar theory formulated in the space-fixed reference-frame [M. Ivanov, M.-L. Dubernet, and D. Babikov, J. Chem. Phys. 140, 134301 (2014)]. Here, the goal was to develop an approximate computationally affordable treatment of the rotationally inelastic scattering and apply it to H{sub 2}O + He. We found that MQCT is somewhat less accurate at lower scattering energies. For example, below E = 1000 cm{sup −1} the typical errors in the values of inelastic scattering cross sections are on the order of 10%. However, at higher scattering energies MQCT method appears to be rather accurate. Thus, at scattering energies above 2000 cm{sup −1} the errors are consistently in the range of 1%–2%, which is basically our convergence criterion with respect to the number of trajectories. At these conditions our MQCT method remains computationally affordable. We found that computational cost of the fully-coupled MQCT calculations scales as n{sup 2}, where n is the number of channels. This is more favorable than the full-quantum inelastic scattering calculations that scale as n{sup 3}. Our conclusion is that for complex systems (heavy collision partners with many internal states) and at higher scattering energies MQCT may offer significant computational advantages.

  16. Future National Reference Frames for the United States

    Science.gov (United States)

    Stone, W. A.

    2015-12-01

    The mission of the National Oceanic and Atmospheric Administration's National Geodetic Survey (NGS) is "to define, maintain and provide access to the National Spatial Reference System (NSRS) to meet our nation's economic, social, and environmental needs." NSRS is the nation's system of latitude, longitude, elevation, and related geophysical and geodetic models and tools, which provides a consistent spatial reference framework for the broad spectrum of geoscientific applications and other positioning-related requirements. Technological developments - notably Global Navigation Satellite Systems (GNSS) - and user accuracy requirements necessitate that NGS endeavor to modernize the NSRS. Preparations are underway by NGS for a comprehensive NSRS makeover, to be completed in 2022 and delivered through a new generation of horizontal and vertical datums (reference frames), featuring unprecedented accuracy, repeatability, and efficiency of access. This evolution is outlined in the "National Geodetic Survey Ten-Year Strategic Plan, 2013-2023." This presentation will outline the motivation for this effort and the history, current status and planned evolution of NSRS. Fundamental to the delivery of the future reference frame paradigm are new geometric and geopotential (elevation) frameworks. The new geometric reference frame, realized through GNSS Continuously Operating Reference Stations (CORS), will replace the North American Datum of 1983 (NAD83) and will provide the nationwide framework for determination of latitude, longitude, and ellipsoid height. Designed to complement the new geometric reference frame, a corresponding geopotential reference frame - based on a national gravimetric geoid and replacing the North American Vertical Datum of 1988 (NAVD88) - will be developed and co-released. The gravimetric geoid - or definitional reference surface (zero elevation) - for the future geopotential reference frame will be built in part from airborne gravimetric data collected in

  17. Hot Experimental Facility reference flowsheet

    Energy Technology Data Exchange (ETDEWEB)

    North, E.D.

    1982-01-01

    This paper is a useful set of background information of HEF flowsheets, although many changes have been made in the past three years. The HEF reference flowsheet is a modified high-acid PUREX flowsheet capable of operating in the coprocessing mode or with full partitioning of U and Pu. Adequate decontamination factors are provided to purify high-burnup, fast breeder-reactor fuels to levels required for recycle back to a fuel fabrication facility. Product streams are mixed U-Pu oxide and uranium oxide. No contaminated liquid wastes are intentionally discharged to the environment. All wastes are solidified and packaged for appropriate disposal. Acid and water are recovered for internal recycle. Excess water is treated and discharged from the plant stack. Several changes have been made in the reference flowsheet since that time, and these are noted briefly.

  18. The Lyman alpha reference sample

    DEFF Research Database (Denmark)

    Hayes, M.; Östlin, G.; Schaerer, D.

    2013-01-01

    We report on new imaging observations of the Lyman alpha emission line (Lyα), performed with the Hubble Space Telescope, that comprise the backbone of the Lyman alpha Reference Sample. We present images of 14 starburst galaxies at redshifts 0.028 Reference Sample. We present images of 14 starburst galaxies at redshifts 0.028 ... with quantities that scale with dust content, in the sense that a low dust abundance is a necessary requirement (although not the only one) in order to spread Lyα photons throughout the interstellar medium and drive a large extended Lyα halo. © 2013. The American Astronomical Society. All rights reserved....

  19. Savings, subgoals, and reference points

    Directory of Open Access Journals (Sweden)

    Helen Colby

    2013-01-01

    Full Text Available Decision makers often save money for a specific goal by forgoing discretionary consumption and instead putting the money toward the savings goal. We hypothesized that reference points can be exploited to enhance this type of saving. In two hypothetical scenario studies, subjects made judgments of their likelihood to forgo a small expenditure in order to put the money toward the savings goal. In Experiment 1, judgments were higher if the savings goal was presented as composed of weekly subgoals (e.g., save $60 per week to buy a $180 iPod. Experiment 2 replicated this finding and demonstrated that the subgoal manipulation increased judgments of likelihood to save money only when the money saved from the foregone consumption would allow the decision maker to meet the weekly subgoal exactly (not under or overshoot it. These results suggest a reference point mechanism and point to ways that behavioral decision research can be harnessed to improve economic behaviors.

  20. Project X: Accelerator Reference Design

    CERN Document Server

    Holmes, S D; Chase, B; Gollwitzer, K; Johnson, D; Kaducak, M; Klebaner, A; Kourbanis, I; Lebedev, V; Leveling, A; Li, D; Nagaitsev, S; Ostroumov, P; Pasquinelli, R; Patrick, J; Prost, L; Scarpine, V; Shemyakin, A; Solyak, N; Steimel, J; Yakovlev, V; Zwaska, R

    2013-01-01

    Part 1 of "Project X: Accelerator Reference Design, Physics Opportunities, Broader Impacts". Part 1 contains the volume Preface and a description of the conceptual design for a high-intensity proton accelerator facility being developed to support a world-leading program of Intensity Frontier physics over the next two decades at Fermilab. Subjects covered include performance goals, the accelerator physics design, and the technological basis for such a facility.

  1. A note on reference limits

    OpenAIRE

    Huang, Jing-Ye; Chen, Lin-An; Welsh, A. H.

    2010-01-01

    We introduce a conceptual framework within which the problem of setting reference intervals is one of estimating population parameters. The framework enables us to broaden the possibilities for inference by showing how to create confidence intervals for population intervals. We propose a new kind of interval (the γ-mode interval) as the population parameter of interest and show how to estimate and make optimal inference about this interval. Finally, we clarify the relationship between our ref...

  2. National Software Reference Library (NSRL)

    Science.gov (United States)

    National Software Reference Library (NSRL) (PC database for purchase)   A collaboration of the National Institute of Standards and Technology (NIST), the National Institute of Justice (NIJ), the Federal Bureau of Investigation (FBI), the Defense Computer Forensics Laboratory (DCFL),the U.S. Customs Service, software vendors, and state and local law enforement organizations, the NSRL is a tool to assist in fighting crime involving computers.

  3. HANFORD WASTE MINEROLOGY REFERENCE REPORT

    Energy Technology Data Exchange (ETDEWEB)

    DISSELKAMP RS

    2010-06-18

    This report lists the observed mineral phase phases present in the Hanford tanks. This task was accomplished by performing a review of numerous reports using experimental techniques including, but not limited to: x-ray diffraction, polarized light microscopy, scanning electron microscopy, transmission electron microscopy, energy dispersive spectroscopy, electron energy loss spectroscopy, and particle size distribution analyses. This report contains tables that can be used as a quick reference to identify the crystal phases present observed in Hanford waste.

  4. HANFORD WASTE MINERALOGY REFERENCE REPORT

    Energy Technology Data Exchange (ETDEWEB)

    DISSELKAMP RS

    2010-06-29

    This report lists the observed mineral phases present in the Hanford tanks. This task was accomplished by performing a review of numerous reports that used experimental techniques including, but not limited to: x-ray diffraction, polarized light microscopy, scanning electron microscopy, transmission electron microscopy, energy dispersive spectroscopy, electron energy loss spectroscopy, and particle size distribution analyses. This report contains tables that can be used as a quick reference to identify the crystal phases observed in Hanford waste.

  5. World Reference Center for Arboviruses.

    Science.gov (United States)

    1983-01-01

    Greece. Monoclonal antibodies for Rift Valley fever were generally specific, all IgG, reacted the same in HI and neutralization when directed to...demonstrate transmission by nectar, failed to show any marked effects of colonization through 6 generations on susceptibility to infection, and failed...were referred for testing by the Centro Nacional de Microbiologia , Madrid. The sera were tested and found negative by HI with dengue and Rift Valley

  6. Tv & video engineer's reference book

    CERN Document Server

    Jackson, K G

    1991-01-01

    TV & Video Engineer's Reference Book presents an extensive examination of the basic television standards and broadcasting spectrum. It discusses the fundamental concepts in analogue and digital circuit theory. It addresses studies in the engineering mathematics, formulas, and calculations. Some of the topics covered in the book are the conductors and insulators, passive components, alternating current circuits; broadcast transmission; radio frequency propagation; electron optics in cathode ray tube; color encoding and decoding systems; television transmitters; and remote supervision of unatten

  7. Microgrid cyber security reference architecture.

    Energy Technology Data Exchange (ETDEWEB)

    Veitch, Cynthia K.; Henry, Jordan M.; Richardson, Bryan T.; Hart, Derek H.

    2013-07-01

    This document describes a microgrid cyber security reference architecture. First, we present a high-level concept of operations for a microgrid, including operational modes, necessary power actors, and the communication protocols typically employed. We then describe our motivation for designing a secure microgrid; in particular, we provide general network and industrial control system (ICS)-speci c vulnerabilities, a threat model, information assurance compliance concerns, and design criteria for a microgrid control system network. Our design approach addresses these concerns by segmenting the microgrid control system network into enclaves, grouping enclaves into functional domains, and describing actor communication using data exchange attributes. We describe cyber actors that can help mitigate potential vulnerabilities, in addition to performance bene ts and vulnerability mitigation that may be realized using this reference architecture. To illustrate our design approach, we present a notional a microgrid control system network implementation, including types of communica- tion occurring on that network, example data exchange attributes for actors in the network, an example of how the network can be segmented to create enclaves and functional domains, and how cyber actors can be used to enforce network segmentation and provide the neces- sary level of security. Finally, we describe areas of focus for the further development of the reference architecture.

  8. Programming Windows® Embedded CE 60 Developer Reference

    CERN Document Server

    Boling, Douglas

    2010-01-01

    Get the popular, practical reference to developing small footprint applications-now updated for the Windows Embedded CE 6.0 kernel. Written by an authority on embedded application development, this book focuses in on core operating concepts and the Win32 API. It delivers extensive code samples and sample projects-helping you build proficiency creating innovative Windows applications for a new generation of devices. Discover how to: Create complex applications designed for the unique requirements of embedded devicesManage virtual memory, heaps, and the stack to minimize your memory footprintC

  9. 基于蒸渗仪实测的参考作物蒸散发模型北京地区适用性评价%Applicability assessment of reference evapotranspiration models in Beijing based on lysimeter measurement

    Institute of Scientific and Technical Information of China (English)

    袁小环; 杨学军; 陈超; 武菊英

    2014-01-01

    参考作物蒸散发(ET0,reference evapotranspiration)是计算植被耗水量、分析区域水分平衡、管理水资源的基本参数。由于区域间气象条件的差异,ET0模型在不同地区表现出不同的适用性。蒸渗仪实测是欧美地区评价参考作物蒸散发模型的经典方法,而中国尚少研究,华北地区未见报道。2012年生长季(4-10月),应用自动称重式蒸渗仪实测高羊茅草坪蒸散评价了Penman-Monteith (FAO-56)、Hargreaves-Samani、Priestley-Taylor、Penman-van Bavel模型在北京地区的适用性。在2个蒸渗仪中建植冷季型高羊茅草坪,以获得ET0标准数据。试验地安装Dynamet气象站,自动测量并记录气象数据:空气温度、空气相对湿度、太阳总辐射和高度2m的风速,用于模型计算参考作物蒸散发。应用线性回归与均方根误差(RMSE)、一致性指数(d)2个指标评价模型的预测准确性。研究结果表明,太阳总辐射与月蒸散之间呈现较强的线性关系(R2=0.95,p=2.72×10-7),说明太阳辐射能量是驱动SPAC(soil-plant-atmosphere continuum)系统中水分从植被向大气运动的主要动力。随着时间尺度减小,模型的估算准确度降低。由于模型的输入参数不同,在 ET0计算中出现了不同方向的偏差。月尺度上, Priestley-Taylor模型低估,而Penman-Monteith、Hargreaves-Samani和Penman-van Bavel模型高估了蒸散。日尺度上,Hargreaves-Samani模型和Penman-van Bavel模型略微高估了日蒸散,比率分别为1.0167和1.0526;Penman-Monteith 模型和 Priestly-Taylor 模型低估了日蒸散,比率分别为0.8204和0.7593。时尺度上,除了Priestly-Taylor模型全部得出最低的数值,其余模型在不同天气类型下得出不同的计算结果。综合月、日、时3个时间尺度的评价结果,Penman-van Bavel是最准确的ET0计算公式,RMSE分别为0.63 mm/d(月)、1.43 mm

  10. 奶粉中亚硝酸盐和硝酸盐成分分析基体标准物质的应用%The Application of Matrix Reference Material of Nitrite and Nitrate in Milk Powder

    Institute of Scientific and Technical Information of China (English)

    王智聪; 冯炫; 余笑波; 沙跃兵

    2016-01-01

    建立了奶粉中亚硝酸盐和硝酸盐含量准确测定的方法,以奶粉中亚硝酸盐和硝酸盐成分分析基体标准物质作为质控品进行方法学的考察与评价。奶粉样品经低温-酸沉淀/固相萃取净化,采用离子色谱-电导检测分析。结果表明,亚硝酸盐(以NO2-计)和硝酸盐(以NO3-计)分别在0.010μg/mL~0.500μg/mL和0.100μg/mL~5.00μg/mL的范围内线性良好,相关系数(r)均大于0.99,在奶粉中的最低定量限分别为0.400/4.00 mg/kg(NO2-/NO3-);亚硝酸盐和硝酸盐测定方法中的基质效应分别为95.6%/99.6%(NO2-/NO3-);基于基质效应的加标回收率分别为90.3%/87.1%(NO2-/NO3-);以奶粉基体标准物质进行方法学考察,方法的准确性分别为90.5%/89.9%(NO2-/NO3-),精密度(RSD)分别为2.1%/0.7%(NO2-/NO3-)。奶粉中亚硝酸盐和硝酸盐成分分析基体标准物质作为质控品,可以用于分析测试方法的评价、实验室结果的比对,以及相关行业奶粉中亚硝酸盐和硝酸盐含量监测量值传递体系的建立,为奶粉的质量控制和安全评价提供保障。%An accurate method was developed for the analysis of nitrite and nitrate in milk powder, which using matrix reference material as quality control tool to evaluate the analytical method. Milk powder sample was se-quence cleaned by low temperature-acid precipitation and sold phase extraction, and then analyzed by ion chromatography-conductivity detector. The results showed that nitrite and nitrate displayed good linear relation-ships over the range of 0.010μg/mL-0.500μg/mL(NO2-) and 0.100μg/mL-5.00μg/mL(NO3-), with correla-tion coefficients greater than 0.99. The quantitation limits of nitrite and nitrate in milk powder were 0.400 mg/kg and 4.00 mg/kg. The matrix effects of the method for nitrite and nitrate were 95.6%and 99.6%, and the addi-tion recoveries based on matrix effect were 90.3%and 87.1%separately. The

  11. Portable fluorescence meter with reference backscattering channel

    Science.gov (United States)

    Kornilin, Dmitriy V.; Grishanov, Vladimir N.; Zakharov, Valery P.; Burkov, Dmitriy S.

    2016-09-01

    Methods based on fluorescence and backscattering are intensively used for determination of the advanced glycation end products (AGE) concentration in the biological tissues. There are strong correlation between the AGE concentration and the severity of such diseases like diabetes, coronary heart disease and renal failure. This fact can be used for diagnostic purposes in medical applications. Only few investigations in this area can be useful for development of portable and affordable in vivo AGE meter because the most of them are oriented on using spectrometers. In this study we describe the design and the results of tests on volunteers of portable fluorescence meter based on two photodiodes. One channel of such fluorimeter is used for measurement of the autofluorescence (AF) intensity, another one - for the intensity of elastically scattered radiation, which can be used as a reference. This reference channel is proposed for normalization of the skin autofluorescence signal to the human skin photo type. The fluorimeter, that was developed is relatively compact and does not contain any expensive optical and electronic components. The experimental results prove that proposed tool can be used for the AGE estimation in human skin.

  12. Portals Reference Implementation v. 1.0

    Energy Technology Data Exchange (ETDEWEB)

    2016-04-15

    The Portals reference implementation is based on the Portals 4.X API, published by Sandia National Laboratories as a freely available public document. It is designed to be an implementation of the Portals Networking Application Programming Interface and is used by several other upper layer protocols like SHMEM, GASNet and MPI. It is implemented over existing networks, specifically Ethernet and InfiniBand networks. This implementation provides Portals networks functionality and serves as a software emulation of Portals compliant networking hardware. It can be used to develop software using the Portals API prior to the debut of Portals networking hardware, such as Bull’s BXI interconnect, as well as a substitute for portals hardware on development platforms that do not have Portals compliant hardware. The reference implementation provides new capabilities beyond that of a typical network, namely the ability to have messages matched in hardware in a way compatible with upper layer software such as MPI or SHMEM. It also offers methods of offloading network operations via triggered operations, which can be used to create offloaded collective operations. Specific details on the Portals API can be found at http://portals4.org.

  13. On combining reference data to improve imputation accuracy.

    Directory of Open Access Journals (Sweden)

    Jun Chen

    Full Text Available Genotype imputation is an important tool in human genetics studies, which uses reference sets with known genotypes and prior knowledge on linkage disequilibrium and recombination rates to infer un-typed alleles for human genetic variations at a low cost. The reference sets used by current imputation approaches are based on HapMap data, and/or based on recently available next-generation sequencing (NGS data such as data generated by the 1000 Genomes Project. However, with different coverage and call rates for different NGS data sets, how to integrate NGS data sets of different accuracy as well as previously available reference data as references in imputation is not an easy task and has not been systematically investigated. In this study, we performed a comprehensive assessment of three strategies on using NGS data and previously available reference data in genotype imputation for both simulated data and empirical data, in order to obtain guidelines for optimal reference set construction. Briefly, we considered three strategies: strategy 1 uses one NGS data as a reference; strategy 2 imputes samples by using multiple individual data sets of different accuracy as independent references and then combines the imputed samples with samples based on the high accuracy reference selected when overlapping occurs; and strategy 3 combines multiple available data sets as a single reference after imputing each other. We used three software (MACH, IMPUTE2 and BEAGLE for assessing the performances of these three strategies. Our results show that strategy 2 and strategy 3 have higher imputation accuracy than strategy 1. Particularly, strategy 2 is the best strategy across all the conditions that we have investigated, producing the best accuracy of imputation for rare variant. Our study is helpful in guiding application of imputation methods in next generation association analyses.

  14. Semantic Features for Classifying Referring Search Terms

    Energy Technology Data Exchange (ETDEWEB)

    May, Chandler J.; Henry, Michael J.; McGrath, Liam R.; Bell, Eric B.; Marshall, Eric J.; Gregory, Michelle L.

    2012-05-11

    When an internet user clicks on a result in a search engine, a request is submitted to the destination web server that includes a referrer field containing the search terms given by the user. Using this information, website owners can analyze the search terms leading to their websites to better understand their visitors needs. This work explores some of the features that can be used for classification-based analysis of such referring search terms. We present initial results for the example task of classifying HTTP requests countries of origin. A system that can accurately predict the country of origin from query text may be a valuable complement to IP lookup methods which are susceptible to the obfuscation of dereferrers or proxies. We suggest that the addition of semantic features improves classifier performance in this example application. We begin by looking at related work and presenting our approach. After describing initial experiments and results, we discuss paths forward for this work.

  15. Shock wave science and technology reference library

    CERN Document Server

    2009-01-01

    This book, as a volume of the Shock Wave Science and Technology Reference Library, is primarily concerned with detonation waves or compression shock waves in reactive heterogeneous media, including mixtures of solid, liquid and gas phases. The topics involve a variety of energy release and control processes in such media - a contemporary research field that has found wide applications in propulsion and power, hazard prevention as well as military engineering. The six extensive chapters contained in this volume are: - Spray Detonation (SB Murray and PA Thibault) - Detonation of Gas-Particle Flow (F Zhang) - Slurry Detonation (DL Frost and F Zhang) - Detonation of Metalized Composite Explosives (MF Gogulya and MA Brazhnikov) - Shock-Induced Solid-Solid Reactions and Detonations (YA Gordopolov, SS Batsanov, and VS Trofimov) - Shock Ignition of Particles (SM Frolov and AV Fedorov) Each chapter is self-contained and can be read independently of the others, though, they are thematically interrelated. They offer a t...

  16. Reference frame independent quantum key distribution

    CERN Document Server

    Laing, Anthony; Rarity, John G; O'Brien, Jeremy L

    2010-01-01

    We describe a quantum key distribution protocol based on pairs of entangled qubits that generates a secure key between two partners in an environment of unknown and slowly varying reference frame. A direction of particle delivery is required, but the phases between the computational basis states need not be known or fixed. The protocol can simplify the operation of existing setups and has immediate applications to emerging scenarios such as earth-to-satellite links and the use of integrated photonic waveguides. We compute the asymptotic secret key rate for a two-qubit source, which coincides with the rate of the six-state protocol for white noise. We give the generalization of the protocol to higher-dimensional systems and detail a scheme for physical implementation in the three dimensional qutrit case.

  17. Reference Electrodes in Metal Corrosion

    Directory of Open Access Journals (Sweden)

    S. Szabó

    2010-01-01

    Full Text Available With especial regard to hydrogen electrode, the theoretical fundamentals of electrode potential, the most important reference electrodes and the electrode potential measurement have been discussed. In the case of the hydrogen electrode, it have been emphasised that there is no equilibrium between the hydrogen molecule (H2 and the hydrogen (H+, hydronium (H3O+ ion in the absence of a suitable catalyst. Taking into account the practical aspects as well, the theorectical basis of working of hydrogen, copper-copper sulphate, mercury-mercurous halide, silver-silver halide, metal-metal oxide, metal-metal sulphate and “Thalamid” electrodes, has been discussed.

  18. [Dietary reference intakes of phosphorus].

    Science.gov (United States)

    Uenishi, Kazuhiro

    2012-10-01

    Phosphorus (P) exists at the all organs and plays important physiological roles in the body. A wide range of food contains P, which is absorbed at a higher level (60-70%) and its insufficiency and deficiency are rarely found. P is used as food additives in many processed food, where risk of overconsumption could be an issue. P has less evidence in terms of nutrition. P has the adequate intake and the tolerable upper intake level, for risk reduction of health disorders associated with excess intake, at the Dietary Reference Intakes for Japanese (2010 edition).

  19. Reference frame for Product Configuration

    DEFF Research Database (Denmark)

    Ladeby, Klaes Rohde; Oddsson, Gudmundur Valur

    2011-01-01

    on configuration systems in the shape of anecdotal reporting on the development of information systems that perhaps support the configuration task – perhaps not. Consequently, the definition of configuration has become ambiguous as different research groups defines configuration differently. This paper propose...... a reference frame for configuration that permits 1) a more precise understanding of a configuration system, 2) a understanding of how the configuration system relate to other systems, and 3) a definition of the basic concepts in configuration. The total configuration system, together with the definition...

  20. Nuclear power a reference handbook

    CERN Document Server

    Henderson, Harry R

    2014-01-01

    In the 21st century, nuclear power has been identified as a viable alternative to traditional energy sources to stem global climate change, and condemned as risky to human health and environmentally irresponsible. Do the advantages of nuclear energy outweigh the risks, especially in light of the meltdown at the Fukushima plant in 2011? This guide provides both a comprehensive overview of this critical and controversial technology, presenting reference tools that include important facts and statistics, biographical profiles, a chronology, and a glossary. It covers major controversies and proposed solutions in detail and contains contributions by experts and important stakeholders that provide invaluable perspective on the topic.

  1. Oracle Data Dictionary Pocket Reference

    CERN Document Server

    Kreines, David

    2003-01-01

    If you work with Oracle, then you don't need to be told that the data dictionary is large and complex, and grows larger with each new Oracle release. It's one of the basic elements of the Oracle database you interact with regularly, but the sheer number of tables and views makes it difficult to remember which view you need, much less the name of the specific column. Want to make it simpler? The Oracle Data Dictionary Pocket Reference puts all the information you need right at your fingertips. Its handy and compact format lets you locate the table and view you need effortlessly without stoppin

  2. 33 CFR 183.310 - Reference areas.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Reference areas. 183.310 Section... of 2 Horsepower or Less General § 183.310 Reference areas. (a) The forward reference area of a boat... aft reference area of a boat is the aftmost two feet of the top surface of the hull or deck,...

  3. 33 CFR 183.210 - Reference areas.

    Science.gov (United States)

    2010-07-01

    ... 33 Navigation and Navigable Waters 2 2010-07-01 2010-07-01 false Reference areas. 183.210 Section... of More Than 2 Horsepower General § 183.210 Reference areas. (a) The forward reference area of a boat...) The aft reference area of a boat is the aft most two feet of the top surface of the hull or deck,...

  4. Using Pin as a Memory Reference Generator for Multiprocessor Simulation

    Energy Technology Data Exchange (ETDEWEB)

    McCurdy, C

    2005-10-22

    In this paper we describe how we have used Pin to generate a multithreaded reference stream for simulation of a multiprocessor on a uniprocessor. We have taken special care to model as accurately as possible the effects of cache coherence protocol state, and lock and barrier synchronization on the performance of multithreaded applications running on multiprocessor hardware. We first describe a simplified version of the algorithm, which uses semaphores to synchronize instrumented application threads and the simulator on every memory reference. We then describe modifications to that algorithm to model the microarchitectural features of the Itanium2 that affect the timing of memory reference issue. An experimental evaluation determines that while cycle-accurate multithreaded simulation is possible using our approach, the use of semaphores has a negative impact on the performance of the simulator.

  5. Application of reference gene for real-time RT-PCR%内参照基因在实时荧光定量RT-PCR检测中的应用

    Institute of Scientific and Technical Information of China (English)

    陈瑾歆; 陈建业; 李云祥

    2011-01-01

    目的 建立测定内参照β-actin表达量的实时荧光定量RT-PCR两步法检测方法.方法 根据Genbank 中人β-actin保守区域序列设计荧光PCR适用的引物和探针,构建质粒标准品建立标准曲线用于荧光PCR相对定量,检测荧光PCR方法的特异性和重复性.结果 建立了人β-actin实时荧光RT-PCR检测方法.结论 本实验建立的人β-actin表达实时荧光RT-PCR两步法检测方法特异性和重复性较好,为β-actin作为定量RT-PCR中内参照基因进行人其他功能基因和病原基因表达的定量分析奠定了基础.%Objective To establish a Taqman real-time RT-PCR 2-step assay for quantitative detection of the expression of human β-actin. Methods Specific primers and probes were designed for real-time RT-PCR according to β-actin cDNA sequence. Plasmid standard preparations were constructed by T-A clone, extracted and prepared for establishing standard curve used for relative quantification real-time RT-PCR. The expression levels of β-actin were measured by real-time RT-PCR in HepG2 cells to detect the specificity and reproducibility of real-time RT-PCR assay. Results An effective real-time RT-PCR assay was established for detecting β-actin mRNA expression levels.Conclusions The real-time PCR assay for the expression of β-actin is a sensitive, specific tool for quantitative assay of mRNA expression levels of other gene when using β-actin as reference genes.

  6. 一种新静力扣除方案在AREM中的应用与试验%The application and experimentation of a new hydrostatic extraction of reference atmosphere in AREM

    Institute of Scientific and Technical Information of China (English)

    吴水清; 徐幼平; 胡邦辉; 程锐; 杨支中

    2013-01-01

    A new scheme of reference atmosphere is introduced to modify the hydrostatic extraction of AREM dynamic framework in this pa-per. A representative storm case is selected to make post-prediction simulation experimentation to validate the effects of the modified model. The results show that this new extraction does better for strong precipitation prediction. There are good impacts on the range, intensity and central location of rainstorms and severe ones. The new extraction improves AREM’s forecast exactitude of meteorological factor fields, espe-cially the prediction of temperature and zonal wind in the middle and low troposphere and low stratosphere has been more remarkably im-proved comparing with the non-revised model. A lot of simulations in flood season validate the results mentioned above. The new hydrostatic extraction is reasonable and effectual.%  引入一种新的参考大气方案,对AREM模式动力框架进行静力扣除修改,并选取暴雨个例进行后报模拟试验,考察模式改进后对暴雨过程的预报效果。试验结果表明:新静力扣除方案对模式预报强降水有较好改进,其主要表现在暴雨、大暴雨范围和强度及其中心位置预报上;新方案也提高了模式对气象要素场的预报准确度,特别是对流层中下层及下平流层的温度和纬向风预报,较模式修改前有了较明显的改进。汛期批量试验进一步证实了以上结果,该新静力扣除方案合理有效。

  7. Superior cross-species reference genes: a blueberry case study.

    Science.gov (United States)

    Die, Jose V; Rowland, Lisa J

    2013-01-01

    The advent of affordable Next Generation Sequencing technologies has had major impact on studies of many crop species, where access to genomic technologies and genome-scale data sets has been extremely limited until now. The recent development of genomic resources in blueberry will enable the application of high throughput gene expression approaches that should relatively quickly increase our understanding of blueberry physiology. These studies, however, require a highly accurate and robust workflow and make necessary the identification of reference genes with high expression stability for correct target gene normalization. To create a set of superior reference genes for blueberry expression analyses, we mined a publicly available transcriptome data set from blueberry for orthologs to a set of Arabidopsis genes that showed the most stable expression in a developmental series. In total, the expression stability of 13 putative reference genes was evaluated by qPCR and a set of new references with high stability values across a developmental series in fruits and floral buds of blueberry were identified. We also demonstrated the need to use at least two, preferably three, reference genes to avoid inconsistencies in results, even when superior reference genes are used. The new references identified here provide a valuable resource for accurate normalization of gene expression in Vaccinium spp. and may be useful for other members of the Ericaceae family as well.

  8. Reference ballistic imaging database performance.

    Science.gov (United States)

    De Kinder, Jan; Tulleners, Frederic; Thiebaut, Hugues

    2004-03-10

    Ballistic imaging databases allow law enforcement to link recovered cartridge cases to other crime scenes and to firearms. The success of these databases has led many to propose that all firearms in circulation be entered into a reference ballistic image database (RBID). To assess the performance of an RBID, we fired 4200 cartridge cases from 600 9mm Para Sig Sauer model P226 series pistols. Each pistol fired two Remington cartridges, one of which was imaged in the RBID, and five additional cartridges, consisting of Federal, Speer, Winchester, Wolf, and CCI brands. Randomly selected samples from the second series of Remington cartridge cases and from the five additional brands were then correlated against the RBID. Of the 32 cartridges of the same make correlated against the RBID, 72% ranked in the top 10 positions. Likewise, of the 160 cartridges of the five different brands correlated against the database, 21% ranked in the top 10 positions. Generally, the ranking position increased as the size of the RBID increased. We obtained similar results when we expanded the RBID to include firearms with the same class characteristics for breech face marks, firing pin impressions, and extractor marks. The results of our six queries against the RBID indicate that a reference ballistics image database of new guns is currently fraught with too many difficulties to be an effective and efficient law enforcement tool.

  9. Hypertext Cross-Reference Utilities

    Science.gov (United States)

    Warren-Smith, R. F.; Draper, P. W.

    This document describes a set of ``Hypertext Cross-Reference Utilities'' (HTX) which are designed to help maintain large documentation sets whose constituent documents are written using the Hypertext Markup Languagee (HTML). The central part of HTX is a hypertext linker, hlink. This allows hyper-links (or cross-references) to be established between related documents in such a way that it is easy to maintain their integrity as individual documents are updated. Information produced by this linking process is also used by other HTX utilities to provide document search facilities and the ability to randomly access any part of a documentation set. This latter capability forms a basis for constructing hypertext help systems for use by other software. The expected readership of this document includes those who read hypertext documentation, those who write it, and those who maintain it, especially those who write and maintain Starlink documentation. Software developers may also be interested in the possibilities for hypertext help that HTX provides.

  10. The soil reference shrinkage curve

    CERN Document Server

    Chertkov, V Y

    2014-01-01

    A recently proposed model showed how a clay shrinkage curve is transformed to the soil shrinkage curve at the soil clay content higher than a critical one. The objective of the present work was to generalize this model to the soil clay content lower a critical one. I investigated (i) the reference shrinkage curve, that is, one without cracks; (ii) the superficial layer of aggregates, with changed pore structure compared with the intraaggregate matrix; and (iii) soils with sufficiently low clay content where there are large pores inside the intraaggregate clay (so-called lacunar pores). The methodology is based on detail accounting for different contributions to the soil volume and water content during shrinkage. The key point is the calculation of the lacunar pore volume variance at shrinkage. The reference shrinkage curve is determined by eight physical soil parameters: (1) oven-dried specific volume; (2) maximum swelling water content; (3) mean solid density; (4) soil clay content; (5) oven-dried structural...

  11. 77 FR 18916 - Production Measurement Documents Incorporated by Reference

    Science.gov (United States)

    2012-03-29

    ... Quantities Using Dynamic Measurement Methods and Volumetric Correction Factors, Part 5--Calculation of Base... introduction of new exploration or production techniques or new technologies. BSEE has reviewed the following... information provided is applicable to other fluids. It is intended for use as a reference manual for...

  12. Hoffmann法在建立儿童红细胞计数参考区间中的应用%The application of Hoffmann method in the establishment of children's reference intervals of erythrocyte count

    Institute of Scientific and Technical Information of China (English)

    冯国双; 宋文琪; 吕亚奇; 聂晓璐; 蔡思雨; 刘天怡; 彭晓霞

    2016-01-01

    Objective To verify the reliability and feasibility of Hoffmann method in establishing pediatric reference intervals (RI) of erythrocyte count.Methods Three hundreds and ninty-two thousands of hospital-based data for erythrocyte count of children aged in 1 to 17,measured by the Sysmex Xs-800i,was collected from Beijing Children's Hospital during January to December 2014.Outliers were removed using the Dixon method,then Hoffmann method was conducted to establish the gender and age stratified pediatric RIs of erythrocyte count.The erythrocyte count of 2 217 healthy children,recruited from Beijing Children's Hospital and Liaocheng Children's Hospital in Shandong province,was conducted as normal reference to verify the reliability of Hoffmann method in establishing RIs and to compare with existing RIs.Results In 4 subgroups as following,male aging 1 to 12 years,male aging 13 to 17 years,female aging 1 to 12 years,female aging 13 to 17 years,the RIs of erythrocyte count established using Hoffmann method were (4.1-5.4) × 1012/L,(4.4-5.7) × 1012/L,(4.0-5.3) × 1012/L,(4.0-5.3) × 1012/L,respectively.The verification results in 2 217 healthy children showed that the proportions of out of range in four subgroups were 6.17%,8.81%,6.22%,7.78%,respectively.Conclusion Hoffmann method produce reliable RIs according with the actual situation in healthy children,which is also convenient and is worth popularizing in clinical practice.%目的 验证Hoffmann法在建立儿童红细胞计数参考区间中的可靠性及可行性.方法 收集北京儿童医院2014年1-12月期间1~17岁39.2万份儿童的红细胞计数结果,所有红细胞计数采用Sysmex Xs-800i自动血液分析仪检测.首先对红细胞计数值采用Dixon法进行异常值剔除,然后用Hoffmann法建立不同性别、不同年龄的儿童红细胞计数的参考区间,并以2014年在北京儿童医院和山东省聊城儿童医院招募的2217名健康体检儿童作为正常对照组,验

  13. A Quick Reference on Hypoxemia.

    Science.gov (United States)

    Bach, Jonathan

    2017-03-01

    This article describes the calculation of the alveolar-arterial gas gradient and its clinical application in determining the cause of hypoxemia. It also outlines the analysis of arterial blood gases and the clinical approach toward diagnosis and treatment of respiratory disease.

  14. New Concepts in Digital Reference

    CERN Document Server

    Lankes, R David

    2009-01-01

    Let us start with a simple scenario: a man asks a woman 'how high is Mount Everest?' The woman replies '29,029 feet'. Nothing could be simpler. Now let us suppose that rather than standing in a room, or sitting on a bus, the man is at his desk and the woman is 300 miles away with the conversation taking place using e-mail. Still simple? Certainly - it happens every day. So why all the bother about digital (virtual, electronic, chat, etc.) reference? If the man is a pilot flying over Mount Everest, the answer matters. If you are a lawyer going to court, the identity of the woman is very importa

  15. The Micropaleontological Reference Centers Network

    Directory of Open Access Journals (Sweden)

    David Lazarus

    2006-09-01

    Full Text Available The Micropaleontological Reference Centers (MRCscomprise large microfossil slide collections prepared from core samples obtained through the Deep Sea Drilling Project(DSDP and Ocean Drilling Program (ODP. The MRCs have been maintained for three decades, largely as a volunteer effort by a global network of curators at more than a dozen institutions (Fig.1, Table 1. They were originallyintended to provide a permanent micropaleontological archive for the DSDP; however, as their geographic and stratigraphic coverage has increased they have become increasingly valuable for research and teaching. This article describes the MRCs and their current usage, identifi es the need to maintain and improve the accuracy of the microfossil taxonomy upon which most DSDP and ODP geochronologyis based, and cites the potential for the future use of the MRCs by the Integrated Ocean Drilling Program (IODP.

  16. 细节管理在整形医院感染管理中的应用研究%Details referred to in the plastic for the application of hospital infection management

    Institute of Scientific and Technical Information of China (English)

    李革红; 福华东; 郭景英; 郭晓博

    2014-01-01

    目的:探讨细节管理在整形医院感染管理中的研究应用,以期筛选出整形医院院感控制的方法,提高医院的医疗水平。方法医院从2012年初开始实施细节管理,2012年出院患者共9895例,实施手术9148例,2011年的出院9815例,共实施手术8981例;比较实施细节管理前后医院感染发生情况。结果2012年发生医院感染166例,感染率0.51%,2011年发生医院感染率1.69%,两年医院感染比较,差异有统计学意义( P<0.05),两年感染部位均以手术部位感染为主,手术部位感染率从2011年的1.50%降至2012年的0.46%,呈下降趋势。结论医院在感染控制工作中,通过强调细节管理,有效地降低了医院感染暴发的可能性,减少了感染的发生,保证了患者在医院的安全。%OBJECTIVE To investigate the research and application of detail management in orthopedic hospital infection management ,so as to filter out the better control methods for plastic surgery hospital infections to improve the hospital′s medical standards .METHODS The hospital had implemented detail management since the early 2012 .In 2012 the number of 9 895 cases discharged and a total of 9 148 cases received surgery ,while in 2011 the numbers were 9 815 and 8 981 cases .Before and after the implementation detail management ,the hospital infection occurrence was compared .RESULTS The occurrence of nosocomial infections in our hospital in 2012 was 166 cases ,and nosocomial infection rate was 0 .51% ,while 2011 ,the infection rate was 1 .69% ,which was significant different between the two years (P<0 .05) .The infection sites in these two years were mainly the sites of surgery ,and the infection rate of surgery sites has been decreased from 1 .5% to 0 .46% ,which was in a decreased trend .CONCLUSION The hospital infection control work ,by emphasizing the detail management ,could effectively reduce the likelihood of

  17. Reference values for pulmonary diffusing capacity for adult native Finns.

    Science.gov (United States)

    Kainu, Annette; Toikka, Jyri; Vanninen, Esko; Timonen, Kirsi L

    2017-04-01

    Measurement standards for pulmonary diffusing capacity were updated in 2005 by the ATS/ERS Task Force. However, in Finland reference values published in 1982 by Viljanen et al. have been used to date. The main aim of this study was to produce updated reference models for single-breath diffusing capacity for carbon monoxide for Finnish adults. Single-breath diffusing capacity for carbon monoxide was measured in 631 healthy non-smoking volunteers (41.5% male). Reference values for diffusing capacity (DLCO), alveolar volume (VA), diffusing capacity per unit of lung volume (DLCO/VA), and lung volumes were calculated using a linear regression model. Previously used Finnish reference values were found to produce too low predicted values, with mean predicted DLCO 111.0 and 104.4%, and DLCO/VA of 103.5 and 102.7% in males and females, respectively. With the European Coalition for Steel and Coal (ECSC) reference values there was a significant sex difference in DLCO/VA with mean predicted 105.4% in males and 92.8% in females (p values for DLCO, DLCO/VA, VA, vital capacity (VC), inspiratory vital capacity (IVC), and inspiratory capacity (IC) are suggested for clinical use to replace technically outdated reference values for clinical applications.

  18. Reference materials and representative test materials: the nanotechnology case

    Energy Technology Data Exchange (ETDEWEB)

    Roebben, G., E-mail: gert.roebben@ec.europa.eu [Joint Research Centre of the European Commission, Institute for Reference Materials and Measurements (Belgium); Rasmussen, K. [Joint Research Centre of the European Commission, Institute for Health and Consumer Protection (Italy); Kestens, V.; Linsinger, T. P. J. [Joint Research Centre of the European Commission, Institute for Reference Materials and Measurements (Belgium); Rauscher, H. [Joint Research Centre of the European Commission, Institute for Health and Consumer Protection (Italy); Emons, H. [Joint Research Centre of the European Commission, Institute for Reference Materials and Measurements (Belgium); Stamm, H. [Joint Research Centre of the European Commission, Institute for Health and Consumer Protection (Italy)

    2013-03-15

    An increasing number of chemical, physical and biological tests are performed on manufactured nanomaterials for scientific and regulatory purposes. Existing test guidelines and measurement methods are not always directly applicable to or relevant for nanomaterials. Therefore, it is necessary to verify the use of the existing methods with nanomaterials, thereby identifying where modifications are needed, and where new methods need to be developed and validated. Efforts for verification, development and validation of methods as well as quality assurance of (routine) test results significantly benefit from the availability of suitable test and reference materials. This paper provides an overview of the existing types of reference materials and introduces a new class of test materials for which the term 'representative test material' is proposed. The three generic concepts of certified reference material, reference material(non-certified) and representative test material constitute a comprehensive system of benchmarks that can be used by all measurement and testing communities, regardless of their specific discipline. This paper illustrates this system with examples from the field of nanomaterials, including reference materials and representative test materials developed at the European Commission's Joint Research Centre, in particular at the Institute for Reference Materials and Measurements (IRMM), and at the Institute for Health and Consumer Protection (IHCP).

  19. Determination of Reference Catalogs for Meridian Observations Using Statistical Method

    Science.gov (United States)

    Li, Z. Y.

    2014-09-01

    The meridian observational data are useful for developing high-precision planetary ephemerides of the solar system. These historical data are provided by the jet propulsion laboratory (JPL) or the Institut De Mecanique Celeste Et De Calcul Des Ephemerides (IMCCE). However, we find that the reference systems (realized by the fundamental catalogs FK3 (Third Fundamental Catalogue), FK4 (Fourth Fundamental Catalogue), and FK5 (Fifth Fundamental Catalogue), or Hipparcos), to which the observations are referred, are not given explicitly for some sets of data. The incompleteness of information prevents us from eliminating the systematic effects due to the different fundamental catalogs. The purpose of this paper is to specify clearly the reference catalogs of these observations with the problems in their records by using the JPL DE421 ephemeris. The data for the corresponding planets in the geocentric celestial reference system (GCRS) obtained from the DE421 are transformed to the apparent places with different hypothesis regarding the reference catalogs. Then the validations of the hypothesis are tested by two kinds of statistical quantities which are used to indicate the significance of difference between the original and transformed data series. As a result, this method is proved to be effective for specifying the reference catalogs, and the missed information is determined unambiguously. Finally these meridian data are transformed to the GCRS for further applications in the development of planetary ephemerides.

  20. Generic Argillite/Shale Disposal Reference Case

    Energy Technology Data Exchange (ETDEWEB)

    Zheng, Liange; Colon, Carlos Jové; Bianchi, Marco; Birkholzer, Jens

    2014-08-08

    properties (parameters) used in these models are different, which not only make inter-model comparisons difficult, but also compromise the applicability of the lessons learned from one model to another model. The establishment of a reference case would therefore be helpful to set up a baseline for model development. A generic salt repository reference case was developed in Freeze et al. (2013) and the generic argillite repository reference case is presented in this report. The definition of a reference case requires the characterization of the waste inventory, waste form, waste package, repository layout, EBS backfill, host rock, and biosphere. This report mainly documents the processes in EBS bentonite and host rock that are potentially important for performance assessment and properties that are needed to describe these processes, with brief description other components such as waste inventory, waste form, waste package, repository layout, aquifer, and biosphere. A thorough description of the generic argillite repository reference case will be given in Jové Colon et al. (2014).

  1. Monolithic Michelson Interferometer as ultra stable wavelength reference

    Science.gov (United States)

    Wan, Xiaoke; Ge, Jian

    2010-07-01

    Ultra-stable Monolithic Michelson interferometer can be an ideal reference for highprecision applications such as RV measurement in planet searching and orbit study. The advantages include wide wavelength range, simple sinusoidal spectral format, and high optical efficiency. In this paper, we report that a monolithic Michelson interferometers has been in-house developed with minimized thermal sensitivity with compensation tuning. With a scanning white light interferometer, the thermal sensitivity is measured ~ 6x10-7/°C at 550 nm and it decreases to zero near 1000 nm. We expect the wideband wavelength reference source to be stabilized better than 0.3 m/s for RV experiments

  2. Java Foundation Classes in a Nutshell Desktop Quick Reference

    CERN Document Server

    Flanagan, David

    1999-01-01

    Java Foundation Classes in a Nutshell is an indispensable quick reference for Java programmers who are writing applications that use graphics or graphical user interfaces. The author of the bestsellingJava in a Nutshell has written fast-paced introductions to the Java APIs that comprise the Java Foundation Classes (JFC), such as the Swing GUI components and Java 2D, so that you can start using these exciting new technologies right away. This book also includes O'Reilly's classic-style, quick-reference material for all of the classes in the javax.swing and java.awt packages and their numerous

  3. LDRD final report on a unified linear reference system

    Energy Technology Data Exchange (ETDEWEB)

    Espinoza, J. Jr.; Mackoy, R.D. [Sandia National Labs., Albuquerque, NM (United States). Decision Support Systems Software Engineering Dept.; Fletcher, D.R. [Univ. of New Mexico, Albuquerque, NM (United States). Alliance for Transportation Research

    1997-06-01

    The purpose of the project was to describe existing deficiencies in Geographic Information Systems for transportation (GIS-T) applications and prescribe solutions that would benefit the transportation community in general. After an in-depth literature search and much consultation with noted transportation experts, the need for a common linear reference system that integrated and supported the planning and operational needs of the transportation community became very apparent. The focus of the project was set on a unified linear reference system and how to go about its requirements definition, design, implementation, and promulgation to the transportation community.

  4. The Reference Forward Model (RFM)

    Science.gov (United States)

    Dudhia, Anu

    2017-01-01

    The Reference Forward Model (RFM) is a general purpose line-by-line radiative transfer model, currently supported by the UK National Centre for Earth Observation. This paper outlines the algorithms used by the RFM, focusing on standard calculations of terrestrial atmospheric infrared spectra followed by a brief summary of some additional capabilities and extensions to microwave wavelengths and extraterrestrial atmospheres. At its most basic level - the 'line-by-line' component - it calculates molecular absorption cross-sections by applying the Voigt lineshape to all transitions up to ±25 cm-1 from line-centre. Alternatively, absorptions can be directly interpolated from various forms of tabulated data. These cross-sections are then used to construct infrared radiance or transmittance spectra for ray paths through homogeneous cells, plane-parallel or circular atmospheres. At a higher level, the RFM can apply instrumental convolutions to simulate measurements from Fourier transform spectrometers. It can also calculate Jacobian spectra and so act as a stand-alone forward model within a retrieval scheme. The RFM is designed for robustness, flexibility and ease-of-use (particularly by the non-expert), and no claims are made for superior accuracy, or indeed novelty, compared to other line-by-line codes. Its main limitations at present are a lack of scattering and simplified modelling of surface reflectance and line-mixing.

  5. Gender agreement and multiple referents

    Science.gov (United States)

    Finocchiaro, Chiara; Mahon, Bradford Z.; Caramazza, Alfonso

    2010-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana ‘the:fem apple:fem and the: fem banana: fem’) than masculine conjoined noun phrases (e.g., il fiore e il libro ‘the:mas flower: mas and the:mas book:mas’). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.* PMID:21037930

  6. Gender agreement and multiple referents.

    Science.gov (United States)

    Finocchiaro, Chiara; Mahon, Bradford Z; Caramazza, Alfonso

    2008-01-01

    We report a new pattern of usage in current, spoken Italian that has implications for both psycholinguistic models of language production and linguistic theories of language change. In Italian, gender agreement is mandatory for both singular and plural nouns. However, when two or more nouns of different grammatical gender appear in a conjoined noun phrase (NP), masculine plural agreement is required. In this study, we combined on-line and off-line methodologies in order to assess the mechanisms involved in gender marking in the context of multiple referents. The results of two pronoun production tasks showed that plural feminine agreement was significantly more difficult than plural masculine agreement. In a separate study using offline judgements of acceptability, we found that agreement violations in Italian are tolerated more readily in the case of feminine conjoined noun phrases (e.g., la mela e la banana 'the:fem apple:fem and the: fem banana: fem') than masculine conjoined noun phrases (e.g., il fiore e il libro 'the:mas flower: mas and the:mas book:mas'). Implications of these results are discussed both at the level of functional architecture within the language production system and at the level of changes in language use.

  7. Facilitating Physician Access to Medical Reference Information

    OpenAIRE

    2005-01-01

    Context: Computer-based medical reference information is augmenting—and in some cases, replacing—many traditional sources. For Kaiser Permanente (KP) physicians, this change presents both advantages and obstacles to finding medical reference information.

  8. Common Frame of Reference and social justice

    NARCIS (Netherlands)

    Hesselink, M.W.; Satyanarayana, R.

    2009-01-01

    The article "Common Frame of Reference and Social Justice" by Martijn W. Hesselink evaluates the Draft Common Frame of Reference (DCFR) of social justice. It discusses the important areas, namely a common frame of Reference in a broad sense, social justice and contract law, private law and democracy

  9. Frames of Reference in the Classroom

    Science.gov (United States)

    Grossman, Joshua

    2012-01-01

    The classic film "Frames of Reference" effectively illustrates concepts involved with inertial and non-inertial reference frames. In it, Donald G. Ivey and Patterson Hume use the cameras perspective to allow the viewer to see motion in reference frames translating with a constant velocity, translating while accelerating, and rotating--all with…

  10. Virtual Reference Services: Directions and Agendas.

    Science.gov (United States)

    Gray, Suzanne M.

    2000-01-01

    Analyzes Web sites of ten large research libraries in order to establish a basic understanding of how some major libraries are currently providing virtual reference services. Discusses centralization; email reference guidelines; creating a service economy; expanding hours of service; virtual users' needs; and real-time virtual reference.…

  11. Implementing virtual reference services a LITA guide

    CERN Document Server

    Thomsett-Scott, Beth C

    2013-01-01

    Social web technologies present an often confusing array of options for answering user reference questions. Applying 20 years' experience as a reference librarian working through the development of virtual reference and the integration of new tools and technologies into the industry, Thomsett-Scott lays out how libraries are using vendor services such as LibraryH3lp, LibAnswers, and Text a Librarian, as well as free tools like Twitter and Google Voice for their reference needs. Practitioners offer details on virtual reference services such as Twitter Search, instant messaging services such as

  12. Design Reference Missions for Deep-Space Optical Communication

    Science.gov (United States)

    Breidenthal, J.; Abraham, D.

    2016-05-01

    We examined the potential, but uncertain, NASA mission portfolio out to a time horizon of 20 years, to identify mission concepts that potentially could benefit from optical communication, considering their communications needs, the environments in which they would operate, and their notional size, weight, and power constraints. A set of 12 design reference missions was selected to represent the full range of potential missions. These design reference missions span the space of potential customer requirements, and encompass the wide range of applications that an optical ground segment might eventually be called upon to serve. The design reference missions encompass a range of orbit types, terminal sizes, and positions in the solar system that reveal the chief system performance variables of an optical ground segment, and may be used to enable assessments of the ability of alternative systems to meet various types of customer needs.

  13. Fabricating defensible reference standards for the NDA lab

    Energy Technology Data Exchange (ETDEWEB)

    Ceo, R.N.; May, P.K. [Oak Ridge Y-12 Plant, TN (United States)

    1997-11-01

    Nondestructive analysis (NDA) is performed at the Oak Ridge Y-12 Plant in support of the enriched uranium operations. Process materials are analyzed using gamma ray- and neutron-based instruments including segmented gamma scanners, solution assay systems, and an active well coincidence counter. Process wastes are also discarded based on results of these measurements. Good analytical practice, as well as applicable regulations, mandates that these analytical methods be calibrated using reference materials traceable to the national standards base. Reference standards for NDA instruments are not commercially available owing to the large quantities of special nuclear materials involved. Instead, representative materials are selected from each process stream, then thoroughly characterized by methods that are traceable to the national standards base. This paper discusses the process materials to be analyzed, reference materials selected for calibrating each NDA instrument, and details of their characterization and fabrication into working calibrations standards. Example calibration curves are also presented. 4 figs.

  14. jQuery Pocket Reference

    CERN Document Server

    Flanagan, David

    2010-01-01

    "As someone who uses jQuery on a regular basis, it was surprising to discover how much of the library I'm not using. This book is indispensable for anyone who is serious about using jQuery for non-trivial applications."-- Raffaele Cecco, longtime developer of video games, including Cybernoid, Exolon, and Stormlord jQuery is the "write less, do more" JavaScript library. Its powerful features and ease of use have made it the most popular client-side JavaScript framework for the Web. This book is jQuery's trusty companion: the definitive "read less, learn more" guide to the library. jQuery P

  15. User satisfaction with referrals at a collaborative virtual reference service Virtual reference services, Reference services, Referrals, User satisfaction

    Directory of Open Access Journals (Sweden)

    Nahyun Kwon

    2006-01-01

    Full Text Available Introduction. This study investigated unmonitored referrals in a nationwide, collaborative chat reference service. Specifically, it examined the extent to which questions are referred, the types of questions that are more likely to be referred than others, and the level of user satisfaction with the referrals in the collaborative chat reference service. Method. The data analysed for this study were 420 chat reference transaction transcripts along with corresponding online survey questionnaires submitted by the service users. Both sets of data were collected from an electronic archive of a southeastern state public library system that has participated in 24/7 Reference of the Metropolitan Cooperative Library System (MCLS. Results. Referrals in the collaborative chat reference service comprised approximately 30% of the total transactions. Circulation-related questions were the most often referred among all question types, possibly because of the inability of 'outside' librarians to access patron accounts. Most importantly, user satisfaction with referrals was found to be significantly lower than that of completed answers. Conclusion. The findings of this study addressed the importance of distinguishing two types of referrals: the expert research referrals conducive to collaborative virtual reference services; and the re-directional local referrals that increase unnecessary question traffic, thereby being detrimental to effective use of collaborative reference. Continuing efforts to conceptualize referrals in multiple dimensions are anticipated to fully grasp complex phenomena underlying referrals.

  16. WECC Variable Generation Planning Reference Book: Appendices

    Energy Technology Data Exchange (ETDEWEB)

    Makarov, Yuri V.; Du, Pengwei; Etingov, Pavel V.; Ma, Jian; Vyakaranam, Bharat

    2013-05-13

    The document titled “WECC Variable Generation Planning Reference Book”. This book is divided into two volumes; one is the main document (volume 1)and the other is appendices (volume 2). The main document is a collection of the best practices and the information regarding the application and impact of variables generation on power system planning. This volume (appendices) has additional information on the following topics: Probabilistic load flow problems. 2. Additional useful indices. 3. high-impact low-frequency (HILF) events. 4. Examples of wide-area nomograms. 5. Transmission line ratings, types of dynamic rating methods. 6. Relative costs per MW-km of different electric power transmission technologies. 7. Ultra-high voltage (UHV) transmission. 8.High voltage direct current (VSC-HVDC). 9. HVDC. 10. Rewiring of existing transmission lines. 11. High-temperature low sag (HTLS) conductors. 12. The direct method and energy functions for transient stability analysis in power systems. 13.Blackouts caused by voltage instability. 14. Algorithm for parameter continuation predictor-corrector methods. 15. Approximation techniques available for security regions. 16. Impacts of wind power on power system small signals stability. 17. FIDVR. 18. FACTS. 19. European planning standard and practices. 20. International experience in wind and solar energy sources. 21. Western Renewable Energy Zones (WREZ). 22. various energy storage technologies. 23. demand response. 24. BA consolidation and cooperation options. 25. generator power management requirements and 26. European planning guidelines.

  17. First steps towards a scatterometry reference standard

    Science.gov (United States)

    Bodermann, Bernd; Hansen, Poul-Erik; Burger, Sven; Henn, Mark-Alexander; Gross, Hermann; Bär, Markus; Scholze, Frank; Endres, Johannes; Wurm, Matthias

    2012-10-01

    Supported by the European Commission and EURAMET, a consortium of 10 participants from national metrology institutes, universities and companies has recently started a joint research project with the aim of overcoming current challenges in optical scatterometry for traceable linewidth metrology and to establish scatterometry as a traceable and absolute metrological method for dimensional measurements. This requires a thorough investigation of the influence of all significant sample, tool and data analysis parameters, which affect the scatterometric measurement results. For this purpose and to improve the tool matching between scatterometers, CD-SEMs and CD-AFMs, experimental and modelling methods will be enhanced. The different scatterometry methods will be compared with each other and with specially adapted atomic force microscopy (AFM) and scanning electron microscopy (SEM) measurement systems. Additionally novel methods for sophisticated data analysis will be developed and investigated to reach significant reductions of the measurement uncertainties in critical dimension (CD) metrology. To transfer traceability to industrial applications of scatterometry an important step and one final goal of this project is the realisation of different waferbased reference standard materials for calibration of scatterometers. The approaches to reach these goals and first design considerations and preliminary specification of the scatterometry standards are presented and discussed.

  18. Coupled Cluster Methods for Multi-Reference Applications

    Science.gov (United States)

    2011-04-11

    through the direct solution of the Schrodinger equation (or Dirac equation for heavier elements) that describes the electrons in such systems. With...accurate to within expected error bars, requires two elements: new theory developments in how to better solve the Schrodinger equation and their...same excitations can be generated from more than one 0M. When this ansatz is inserted into the Schrodinger equation it leads to a complicated

  19. Reference View Selection in DIBR-Based Multiview Coding.

    Science.gov (United States)

    Maugey, Thomas; Petrazzuoli, Giovanni; Frossard, Pascal; Cagnazzo, Marco; Pesquet-Popescu, Beatrice

    2016-04-01

    Augmented reality, interactive navigation in 3D scenes, multiview video, and other emerging multimedia applications require large sets of images, hence larger data volumes and increased resources compared with traditional video services. The significant increase in the number of images in multiview systems leads to new challenging problems in data representation and data transmission to provide high quality of experience on resource-constrained environments. In order to reduce the size of the data, different multiview video compression strategies have been proposed recently. Most of them use the concept of reference or key views that are used to estimate other images when there is high correlation in the data set. In such coding schemes, the two following questions become fundamental: 1) how many reference views have to be chosen for keeping a good reconstruction quality under coding cost constraints? And 2) where to place these key views in the multiview data set? As these questions are largely overlooked in the literature, we study the reference view selection problem and propose an algorithm for the optimal selection of reference views in multiview coding systems. Based on a novel metric that measures the similarity between the views, we formulate an optimization problem for the positioning of the reference views, such that both the distortion of the view reconstruction and the coding rate cost are minimized. We solve this new problem with a shortest path algorithm that determines both the optimal number of reference views and their positions in the image set. We experimentally validate our solution in a practical multiview distributed coding system and in the standardized 3D-HEVC multiview coding scheme. We show that considering the 3D scene geometry in the reference view, positioning problem brings significant rate-distortion improvements and outperforms the traditional coding strategy that simply selects key frames based on the distance between cameras.

  20. Pseudo-Reference-Based Assembly of Vertebrate Transcriptomes

    Directory of Open Access Journals (Sweden)

    Kyoungwoo Nam

    2016-02-01

    Full Text Available High-throughput RNA sequencing (RNA-seq provides a comprehensive picture of the transcriptome, including the identity, structure, quantity, and variability of expressed transcripts in cells, through the assembly of sequenced short RNA-seq reads. Although the reference-based approach guarantees the high quality of the resulting transcriptome, this approach is only applicable when the relevant reference genome is present. Here, we developed a pseudo-reference-based assembly (PRA that reconstructs a transcriptome based on a linear regression function of the optimized mapping parameters and genetic distances of the closest species. Using the linear model, we reconstructed transcriptomes of four different aves, the white leg horn, turkey, duck, and zebra finch, with the Gallus gallus genome as a pseudo-reference, and of three primates, the chimpanzee, gorilla, and macaque, with the human genome as a pseudo-reference. The resulting transcriptomes show that the PRAs outperformed the de novo approach for species with within about 10% mutation rate among orthologous transcriptomes, enough to cover distantly related species as far as chicken and duck. Taken together, we suggest that the PRA method can be used as a tool for reconstructing transcriptome maps of vertebrates whose genomes have not yet been sequenced.

  1. REFERENCE CASES FOR USE IN THE CEMENTITOUS PARTNERSHIP PROJECT

    Energy Technology Data Exchange (ETDEWEB)

    Langton, C.; Kosson, D.; Garrabrants, A.

    2010-08-31

    The Cementitious Barriers Partnership Project (CBP) is a multi-disciplinary, multi-institution cross cutting collaborative effort supported by the US Department of Energy (DOE) to develop a reasonable and credible set of tools to improve understanding and prediction of the structural, hydraulic and chemical performance of cementitious barriers used in nuclear applications. The period of performance is >100 years for operating facilities and > 1000 years for waste management. The CBP has defined a set of reference cases to provide the following functions: (i) a common set of system configurations to illustrate the methods and tools developed by the CBP, (ii) a common basis for evaluating methodology for uncertainty characterization, (iii) a common set of cases to develop a complete set of parameter and changes in parameters as a function of time and changing conditions, (iv) a basis for experiments and model validation, and (v) a basis for improving conceptual models and reducing model uncertainties. These reference cases include the following two reference disposal units and a reference storage unit: (i) a cementitious low activity waste form in a reinforced concrete disposal vault, (ii) a concrete vault containing a steel high-level waste tank filled with grout (closed high-level waste tank), and (iii) a spent nuclear fuel basin during operation. Each case provides a different set of desired performance characteristics and interfaces between materials and with the environment. Examples of concretes, grout fills and a cementitious waste form are identified for the relevant reference case configurations.

  2. Automated Reference File Generation for HST STIS Using OPUS

    Science.gov (United States)

    Swam, Michael S.; Goodfrooij, Paul; Diaz-Miller, Rosa I.

    A project has been undertaken at the Space Telescope Science Institute (STScI) to automatically generate some types of instrument reference files as soon as the raw exposures are received from the Hubble Space Telescope (HST). This project will start by automatically producing bias and dark reference files for some of the modes of the Space Telescope Imaging Spectrograph's (STIS) CCD camera. Using database tables of planned and received exposures, scripts developed by the STIS instrument group, and the process automation and monitoring features of OPUS, this system will allow monitoring of reference file creation as it occurs on the production systems at STScI. This monitoring occurs through the OPUS Observation Manager (OMG), a Java application running on a potentially remote workstation or personal computer. The automation of the process will not only reduce considerably the time it takes to create these reference files, but also will allow the delivery of accurate bias and dark reference files for STIS shortly after the observations occur, resulting in a much better calibration of the data. This paper will describe the features of the system architecture and the software technologies used to implement them.

  3. Reference frames in virtual spatial navigation are viewpoint dependent

    Directory of Open Access Journals (Sweden)

    Ágoston eTörök

    2014-09-01

    Full Text Available Spatial navigation in the mammalian brain relies on a cognitive map of the environment. Such cognitive maps enable us, for example, to take the optimal route from a given location to a known target. The formation of these maps is naturally influenced by our perception of the environment, meaning it is dependent on factors such as our viewpoint and choice of reference frame. Yet, it is unknown how these factors influence the construction of cognitive maps. Here, we evaluated how various combinations of viewpoints and reference frames affect subjects’ performance when they navigated in a bounded virtual environment without landmarks. We measured both their path length and time efficiency and found that (i ground perspective was associated with egocentric frame of reference, (ii aerial perspective was associated with allocentric frame of reference, (iii there was no appreciable performance difference between first and third person egocentric viewing positions and (iv while none of these effects were dependent on gender, males tended to perform better in general. Our study provides evidence that there are inherent associations between visual perspectives and cognitive reference frames. This result has implications about the mechanisms of path integration in the human brain and may also inspire designs of virtual reality applications. Lastly, we demonstrated the effective use of a tablet PC and spatial navigation tasks for studying spatial and cognitive aspects of human memory.

  4. The use of standardized infinity reference in EEG coherency studies.

    Science.gov (United States)

    Marzetti, L; Nolte, G; Perrucci, M G; Romani, G L; Del Gratta, C

    2007-05-15

    The study of large scale interactions in the brain from EEG signals is a promising method for the identification of functional networks. However, the validity of a large scale parameter is limited by two factors: the use of a non-neutral reference and the artifactual self-interactions between the measured EEG signals introduced by volume conduction. In this paper, we propose an approach to study large scale EEG coherency in which these factors are eliminated. Artifactual self-interaction by volume conduction is eliminated by using the imaginary part of the complex coherency as a measure of interaction and the Reference Electrode Standardization Technique (REST) is used for the approximate standardization of the reference of scalp EEG recordings to a point at infinity that, being far from all possible neural sources, acts like a neutral virtual reference. The application of our approach to simulated and real EEG data shows that the detection of interaction, as opposed to artifacts due to reference and volume conduction, is a goal that can be achieved from the study of a large scale parameter.

  5. REFERENCE CASES FOR USE IN THE CEMENTITIOUS BARRIERS PARTNERSHIP

    Energy Technology Data Exchange (ETDEWEB)

    Langton, C

    2009-01-06

    The Cementitious Barriers Project (CBP) is a multidisciplinary cross cutting project initiated by the US Department of Energy (DOE) to develop a reasonable and credible set of tools to improve understanding and prediction of the structural, hydraulic and chemical performance of cementitious barriers used in nuclear applications. The period of performance is >100 years for operating facilities and > 1000 years for waste management. The CBP has defined a set of reference cases to provide the following functions: (1) a common set of system configurations to illustrate the methods and tools developed by the CBP, (2) a common basis for evaluating methodology for uncertainty characterization, (3) a common set of cases to develop a complete set of parameter and changes in parameters as a function of time and changing conditions, and (4) a basis for experiments and model validation, and (5) a basis for improving conceptual models and reducing model uncertainties. These reference cases include the following two reference disposal units and a reference storage unit: (1) a cementitious low activity waste form in a reinforced concrete disposal vault, (2) a concrete vault containing a steel high-level waste tank filled with grout (closed high-level waste tank), and (3) a spent nuclear fuel basin during operation. Each case provides a different set of desired performance characteristics and interfaces between materials and with the environment. Examples of concretes, grout fills and a cementitious waste form are identified for the relevant reference case configurations.

  6. Establishment of Reference Interval of Serum Prolactin in an Indian Population

    OpenAIRE

    Lahiri, Kapil Deb; Baruah, Mriganka; Ghosh, Joya; Sengupta, Soumendyu

    2014-01-01

    Background: Reference data on serum prolactin levels based on a representative Indian sample are still lacking. The western normative laboratory values used for clinical diagnosis may not be applicable to Indian population. The objective of the study was to measure the serum prolactin levels in healthy Indian male and female in order to establish reference interval and to compare with the available reference intervals. It is a cross- sectional study done in West Bengal, India.

  7. METHOD OF MAXIMAL INFORMATIVE ZONE FOR VIRTUAL REFERENCE STATION DEVELOPMENT IN KINEMATIC SYSTEMS OF GPS NETWORKS

    Directory of Open Access Journals (Sweden)

    R. A. Eminov,

    2013-03-01

    Full Text Available The existing actual material on experimental assessment of positioning error in VRS GPS networks is analyzed where the mobile receiver is provided with virtual reference station. The method of highly informative zone is suggested for removal of initial uncertainty in reference station selection with the aim to develop minimal GPS network consisting of three reference stations. Methodical recommendations and directions are given for the suggested method application.

  8. Web of science: a unique method of cited reference searching.

    Science.gov (United States)

    Sevinc, Alper

    2004-07-01

    The number of times an article is acknowledged as a reference in another article reflects its scientific impact. Citation analysis is one of the parameters for assessing the quality of research published in scientific, technology and social science journals. Web of Science enables users to search current and retrospective multidisciplinary information. Parameters and practical applications evaluating journal and article citation characteristics available through the Science Citation Index are summarized.

  9. Phase-sensitive multiple reference optical coherence tomography (Conference Presentation)

    Science.gov (United States)

    Dsouza, Roshan I.; Subhash, Hrebesh; Neuhaus, Kai; Hogan, Josh; Wilson, Carol; Leahy, Martin

    2016-03-01

    Multiple reference OCT (MR-OCT) is a recently developed novel time-domain OCT platform based on a miniature reference arm optical delay, which utilizes a single miniature actuator and a partial mirror to generate recirculating optical delay for extended axial-scan range. MR-OCT technology promises to fit into a robust and cost-effective design, compatible with integration into consumer-level devices for addressing wide applications in mobile healthcare and biometry applications. Using conventional intensity based OCT processing techniques, the high-resolution structural imaging capability of MR-OCT has been recently demonstrated for various applications including in vivo human samples. In this study, we demonstrate the feasibility of implementing phase based processing with MR-OCT for various functional applications such as Doppler imaging and sensing of blood vessels, and for tissue vibrography applications. The MR-OCT system operates at 1310nm with a spatial resolution of ~26 µm and an axial scan rate of 600Hz. Initial studies show a displacement-sensitivity of ~20 nm to ~120 nm for the first 1 to 9 orders of reflections, respectively with a mirror as test-sample. The corresponding minimum resolvable velocity for these orders are ~2.3 µm/sec and ~15 µm/sec respectively. Data from a chick chorioallantoic membrane (CAM) model will be shown to demonstrate the feasibility of MR-OCT for imaging in-vivo blood flow.

  10. 76 FR 53492 - South Carolina Public Service Authority (Also Referred to as Santee Cooper); Combined Licenses...

    Science.gov (United States)

    2011-08-26

    ... COMMISSION South Carolina Public Service Authority (Also Referred to as Santee Cooper); Combined Licenses for... as Santee Cooper), for two Title 10 of the Code of Federal Regulations (10 CFR) part 52 combined... Service Authority (Also Referred to as Santee Cooper) Application for the Virgil C. Summer Nuclear...

  11. 40 CFR 61.156 - Cross-reference to other asbestos regulations.

    Science.gov (United States)

    2010-07-01

    ... 40 Protection of Environment 8 2010-07-01 2010-07-01 false Cross-reference to other asbestos... for Asbestos § 61.156 Cross-reference to other asbestos regulations. In addition to this subpart, the regulations referenced in Table 1 also apply to asbestos and may be applicable to those sources specified...

  12. Minimize reference sideband generation in microwave PLLs

    Science.gov (United States)

    Goldman, Stan

    1991-02-01

    The processes responsible for producing reference sidebands are outlined, and the sources of coupling to the microwave voltage-controlled oscillator (VCO) tune line including power-supply-generated signals, TTL-controlled interface signals, intermediate programmable-divider signals, and radiated TTL signals are discussed. It is noted that filtering alone is inadequate for reference-sideband suppression, while minimizing the tuning slope and maximizing the reference frequency will result in a reduced reference-sideband level. Minimizing offset currents by using a differential amplifier connection may reduce the reference-sideband level aggravated by an opamp. The selection of a TTL, ECL, or GaAs phase/frequency detector can determine the level of reference sidebands, as well as PCB isolation techniques.

  13. Quantum metrology in coarsened measurement reference

    Science.gov (United States)

    Xie, Dong; Xu, Chunling; Wang, An Min

    2017-01-01

    We investigate the role of coarsened measurement reference, which originates from the coarsened reference time and basis, in quantum metrology. When the measurement is based on one common reference basis, the disadvantage of coarsened measurement can be removed by symmetry. Owing to the coarsened reference basis, the entangled state cannot perform better than the product state for a large number of probe particles in estimating the phase. Given a finite uncertainty of the coarsened reference basis, the optimal number of probe particles is obtained. Finally, we prove that the maximally entangled state always achieves better frequency precision in the case of non-Markovian dephasing than that in the case of Markovian dephasing. The product state is more resistant to the interference of the coarsened reference time than the entangled state.

  14. Skinner's verbal behavior: A reference list

    Science.gov (United States)

    Sundberg, Mark L.; Partington, James W.

    1982-01-01

    The language literature contains many citations to Skinner's book Verbal Behavior (1957), however, most of them are negative and generally unsupportive. The current list of references was assembled to bring readers in contact with the growing body of literature which supports Skinner's work. A total of 136 references were found and divided into two categories, (1) conceptual, and (2) experimental and applied. These references are presented in an effort to stimulate additional research in this important aspect of behavior analysis. PMID:22573391

  15. ["Pro Ana": Psychodynamic References for Anorexia Nervosa].

    Science.gov (United States)

    Siefert, Linda

    2017-02-01

    "Pro Ana": Psychodynamic References for Anorexia Nervosa The internet-based phenomenon "Pro Ana" refers to the eating disorder anorexia nervosa in a positive way. To understand what the phenomenon "Pro Ana" represents, the websites are used as a starting point of the current analysis. Based on these results, similarities and differences between "Pro Ana" and the eating disorder anorexia nervosa are discussed. Furthermore psychodynamic references for anorexia nervosa are derived and finally their importance for treatment motivation will be considered.

  16. Online Citation and Reference Management Tools

    OpenAIRE

    Das, Anup-Kumar

    2015-01-01

    This Unit is on online citation and reference management tools. The tools discussed are Mendeley, CiteULike, Zotero, Google Scholar Library, and EndNote Basic. The features of all the management tools have been discussed with figures, tables, and text boxes. This Unit discusses in details aspects of different Online Citation and Reference Management Tools. Published in the Open Access for Researchers > Module 4: Research Evaluation Metrics > Unit 4: Online Citation and Reference Management T...

  17. Post-Newtonian reference ellipsoid for relativistic geodesy

    Science.gov (United States)

    Kopeikin, Sergei; Han, Wenbiao; Mazurova, Elena

    2016-02-01

    We apply general relativity to construct the post-Newtonian background manifold that serves as a reference spacetime in relativistic geodesy for conducting a relativistic calculation of the geoid's undulation and the deflection of the plumb line from the vertical. We chose an axisymmetric ellipsoidal body made up of a perfect homogeneous fluid uniformly rotating around a fixed axis, as a source generating the reference geometry of the background manifold through Einstein's equations. We then reformulate and extend hydrodynamic calculations of rotating fluids done by a number of previous researchers for astrophysical applications to the realm of relativistic geodesy to set up algebraic equations defining the shape of the post-Newtonian reference ellipsoid. To complete this task, we explicitly perform all integrals characterizing gravitational field potentials inside the fluid body and represent them in terms of the elementary functions depending on the eccentricity of the ellipsoid. We fully explore the coordinate (gauge) freedom of the equations describing the post-Newtonian ellipsoid and demonstrate that the fractional deviation of the post-Newtonian level surface from the Maclaurin ellipsoid can be made much smaller than the previously anticipated estimate based on the astrophysical application of the coordinate gauge advocated by Bardeen and Chandrasekhar. We also derive the gauge-invariant relations of the post-Newtonian mass and the constant angular velocity of the rotating fluid with the parameters characterizing the shape of the post-Newtonian ellipsoid including its eccentricity, a semiminor axis, and a semimajor axis. We formulate the post-Newtonian theorems of Pizzetti and Clairaut that are used in geodesy to connect the geometric parameters of the reference ellipsoid to the physically measurable force of gravity at the pole and equator of the ellipsoid. Finally, we expand the post-Newtonian geodetic equations describing the post-Newtonian ellipsoid to

  18. Referent Salience Affects Second Language Article Use

    Science.gov (United States)

    Trenkic, Danijela; Pongpairoj, Nattama

    2013-01-01

    The effect of referent salience on second language (L2) article production in real time was explored. Thai (-articles) and French (+articles) learners of English described dynamic events involving two referents, one visually cued to be more salient at the point of utterance formulation. Definiteness marking was made communicatively redundant with…

  19. Accuracy of References in Five Entomology Journals.

    Science.gov (United States)

    Kristof, Cynthia

    ln this paper, the bibliographical references in five core entomology journals are examined for citation accuracy in order to determine if the error rates are similar. Every reference printed in each journal's first issue of 1992 was examined, and these were compared to the original (cited) publications, if possible, in order to determine the…

  20. [Determination and verification of reference intervals].

    Science.gov (United States)

    Henny, J; Arnaud, J; Giroud, C; Vassault, A

    2010-12-01

    Based on the original recommendation of the Expert Panel on the Theory of Reference values of the International Federation of Clinical Chemistry and Laboratory Medicine (IFCC-LM), updated guidelines were recently published under the auspices of IFCC and the Clinical and Laboratory Standards Institute. These updated guidelines add valuable improvements (transference, validation and verifying reference intervals).

  1. RASD's New Interlibrary Reference Request Form.

    Science.gov (United States)

    American Libraries, 1985

    1985-01-01

    Introduces information request form developed by Cooperative Reference Services Committee of American Library Association's Reference and Adult Services Division to be used whenever a library cannot supply information requested by a patron and would like to ask another library for assistance. Front of proposed form with sample question is shown.…

  2. Writing references and using citation management software.

    Science.gov (United States)

    Sungur, Mukadder Orhan; Seyhan, Tülay Özkan

    2013-09-01

    The correct citation of references is obligatory to gain scientific credibility, to honor the original ideas of previous authors and to avoid plagiarism. Currently, researchers can easily find, cite and store references using citation management software. In this review, two popular citation management software programs (EndNote and Mendeley) are summarized.

  3. Sense and the Computation of Reference

    NARCIS (Netherlands)

    Muskens, R.A.

    2005-01-01

    The paper shows how ideas that explain the sense of an expression as a method or algorithm for finding its reference, preshadowed in Frege's dictum that sense is the way in which a referent is given, can be formalized on the basis of the ideas in Thomason (1980). To this end, the function that sends

  4. Spatial reference in multiple object tracking.

    Science.gov (United States)

    Jahn, Georg; Papenmeier, Frank; Meyerhoff, Hauke S; Huff, Markus

    2012-01-01

    Spatial reference in multiple object tracking is available from configurations of dynamic objects and static reference objects. In three experiments, we studied the use of spatial reference in tracking and in relocating targets after abrupt scene rotations. Observers tracked 1, 2, 3, 4, and 6 targets in 3D scenes, in which white balls moved on a square floor plane. The floor plane was either visible thus providing static spatial reference or it was invisible. Without scene rotations, the configuration of dynamic objects provided sufficient spatial reference and static spatial reference was not advantageous. In contrast, with abrupt scene rotations of 20°, static spatial reference supported in relocating targets. A wireframe floor plane lacking local visual detail was as effective as a checkerboard. Individually colored geometric forms as static reference objects provided no additional benefit either, even if targets were centered on these forms at the abrupt scene rotation. Individualizing the dynamic objects themselves by color for a brief interval around the abrupt scene rotation, however, did improve performance. We conclude that attentional tracking of moving targets proceeds within dynamic configurations but detached from static local background.

  5. 23 CFR 650.317 - Reference manuals.

    Science.gov (United States)

    2010-04-01

    ... 23 Highways 1 2010-04-01 2010-04-01 false Reference manuals. 650.317 Section 650.317 Highways..., STRUCTURES, AND HYDRAULICS National Bridge Inspection Standards § 650.317 Reference manuals. (a) The... following URL: http://www.transportation.org. (1) The Manual for Bridge Evaluation, First Edition,...

  6. Ready Reference Collections: Thoughts on Trends

    Science.gov (United States)

    Fernandes, Maria Isabel

    2008-01-01

    What is a ready reference collection? A stack of reference books selected according to personal interests? Each institution is unique in its needs and so are the collections that each library carries. The curricula and programs determine the collection development policies and the student population justifies the needs for their implementation. Is…

  7. Gastronomic Reference, Synecdoche, and Political Images.

    Science.gov (United States)

    Brummett, Barry

    1981-01-01

    Defines gastronomic reference, or mention of what public figures eat, as synecdoche. Illustrates how use of this rhetorical device contributed to public figures and public images in the 1980 presidential campaign. Argues that interest in gastronomic reference leads to a broader concern for how synecdoche functions in public discourse. (PD)

  8. Virtual Reference Transcript Analysis: A Few Models.

    Science.gov (United States)

    Smyth, Joanne

    2003-01-01

    Describes the introduction of virtual, or digital, reference service at the University of New Brunswick libraries. Highlights include analyzing transcripts from LIVE (Library Information in a Virtual Environment); reference question types; ACRL (Association of College and Research Libraries) information literacy competency standards; and the Big 6…

  9. Ensuring Quality in a Virtual Reference Environment

    Science.gov (United States)

    Barbier, Pat; Ward, Joyce

    2004-01-01

    Soon after AskALibrarian, Florida's Statewide Virtual Reference Desk, began to offer Chat Reference to the public in 2003, a Quality Assurance Workgroup was established to ensure that the service patrons received would be friendly, accurate, and adequate. To make certain that best practices were used in answering the real time questions, two…

  10. Automation and Job Satisfaction among Reference Librarians.

    Science.gov (United States)

    Whitlatch, Jo Bell

    1991-01-01

    Discussion of job satisfaction and the level of job performance focuses on the effect of automation on job satisfaction among reference librarians. The influence of stress is discussed, a job strain model is explained, and examples of how to design a job to reduce the stress caused by automation are given. (12 references) (LRW)

  11. Grouping in Primary Schools and Reference Processes.

    Science.gov (United States)

    Meijnen, G. W.; Guldemond, H.

    2002-01-01

    Studied reference processes in within-class grouping for elementary school students in the Netherlands in homogeneous (n=16) and heterogeneous (n=14) classes. Findings indicate that homogeneous grouping sets strong reference processes in motion, and processes of comparison have considerably greater effects in homogeneous groups, with negative…

  12. Online Searching in the Reference Room.

    Science.gov (United States)

    Bonta, Bruce D.

    1983-01-01

    Interpersonal relations as necessary part of information transfer process are considered with respect to online searching in reference setting. Major concerns discussed are processes and activities of online searching, role of searcher versus that of end-user, and future trends of reference service in increasingly online environment. Fifty-five…

  13. 47 CFR 15.605 - Cross reference.

    Science.gov (United States)

    2010-10-01

    ... 47 Telecommunication 1 2010-10-01 2010-10-01 false Cross reference. 15.605 Section 15.605 Telecommunication FEDERAL COMMUNICATIONS COMMISSION GENERAL RADIO FREQUENCY DEVICES Access Broadband Over Power Line (Access BPL) § 15.605 Cross reference. (a) The provisions of subparts A and B of this part apply to...

  14. Going Prime Time with Live Chat Reference.

    Science.gov (United States)

    Hoag, Tara J.; Cichanowicz, Edana McCaffrey

    2001-01-01

    Describes the development of the Suffolk Cooperative Library System's live, online chat reference service, a pilot project for public libraries in Suffolk County (New York). Topics include chat software selection; a virtual reference collection; marketing; funding; staffing; evaluation; expanded hours of service; email; and extracting data from…

  15. Uncertainty in Reference and Information Service

    Science.gov (United States)

    VanScoy, Amy

    2015-01-01

    Introduction: Uncertainty is understood as an important component of the information seeking process, but it has not been explored as a component of reference and information service. Method: Interpretative phenomenological analysis was used to examine the practitioner perspective of reference and information service for eight academic research…

  16. Reference Sources: Little Known to Basic

    Science.gov (United States)

    RQ, 1970

    1970-01-01

    This article lists seventy-eight reference sources, and is divided into the following four sections: (1) Useful But Little-Known Reference Tools by John Fetros, (2) The Statesman's Year-Book by James Becker, (3) Single Volume Scientific Encyclopedias by Jack Clarke and (4) Ten Basic Sources of Business and Economic Statistics by James Woy. (MF)

  17. The application evaluation and reference range investigation of ESR-30 auto- dynamic erythrocyte sedimentation rate instrument%ESR-30型全自动动态血沉仪的应用评价与参考区间调查

    Institute of Scientific and Technical Information of China (English)

    路爱丽; 齐振普; 张敏

    2012-01-01

    ). There was hoist trend by age. There were statistical meaning to results in groups older than 61 and younger than 60 for men(Z= -4. 574, P = 0. 000). There was no statistical meaning difference between the results in over-60s and aged 60 or below for women(Z = - 1. 322, P = 0. 185). The reference ranges according to the method were 0 -23. 0 mm/h for men aged 60 or below, 0 - 37. 0 mm/ h for men aged more than 60, and 0 -37. 0 mm/h for women, respectively. Conclusion The result comparability of instrument method and Westergren method is good. Instrument method is suitable for clinical laboratory application. ESR reference ranges of healthy people are quite different from those reported in previous literatures, which should be taken care of.

  18. Standard digital reference images for titanium castings

    CERN Document Server

    American Society for Testing and Materials. Philadelphia

    2010-01-01

    1.1 The digital reference images provided in the adjunct to this standard illustrate various types and degrees of discontinuities occurring in titanium castings. Use of this standard for the specification or grading of castings requires procurement of the adjunct digital reference images, which illustrate the discontinuity types and severity levels. They are intended to provide the following: 1.1.1 A guide enabling recognition of titanium casting discontinuities and their differentiation both as to type and degree through digital radiographic examination. 1.1.2 Example digital radiographic illustrations of discontinuities and a nomenclature for reference in acceptance standards, specifications and drawings. 1.2 The digital reference images consist of seventeen digital files each illustrating eight grades of increasing severity. The files illustrate seven common discontinuity types representing casting sections up to 1-in. (25.4-mm). 1.3 The reference radiographs were developed for casting sections up to 1...

  19. Alcohol references on undergraduate males' Facebook profiles.

    Science.gov (United States)

    Egan, Katie G; Moreno, Megan A

    2011-09-01

    Perceived peer alcohol use is a predictor of consumption in college males; frequent references to alcohol on Facebook may encourage alcohol consumption. Content analysis of college males' Facebook profiles identified references to alcohol. The average age of 225 identified profiles was 19.9 years. Alcohol references were present on 85.3% of the profiles; the prevalence of alcohol was similar across each undergraduate grade. The average number of alcohol references per profile was 8.5 but increased with undergraduate year (p = .003; confidence interval = 1.5, 7.5). Students who were of legal drinking age referenced alcohol 4.5 times more than underage students, and an increase in number of Facebook friends was associated with an increase in displayed alcohol references (p < .001; confidence interval = 0.009, 0.02). Facebook is widely used in the college population; widespread alcohol displays on Facebook may influence social norms and cause increases in male college students' alcohol use.

  20. SYSTEMATIC ERROR REDUCTION: NON-TILTED REFERENCE BEAM METHOD FOR LONG TRACE PROFILER.

    Energy Technology Data Exchange (ETDEWEB)

    QIAN,S.; QIAN, K.; HONG, Y.; SENG, L.; HO, T.; TAKACS, P.

    2007-08-25

    Systematic error in the Long Trace Profiler (LTP) has become the major error source as measurement accuracy enters the nanoradian and nanometer regime. Great efforts have been made to reduce the systematic error at a number of synchrotron radiation laboratories around the world. Generally, the LTP reference beam has to be tilted away from the optical axis in order to avoid fringe overlap between the sample and reference beams. However, a tilted reference beam will result in considerable systematic error due to optical system imperfections, which is difficult to correct. Six methods of implementing a non-tilted reference beam in the LTP are introduced: (1) application of an external precision angle device to measure and remove slide pitch error without a reference beam, (2) independent slide pitch test by use of not tilted reference beam, (3) non-tilted reference test combined with tilted sample, (4) penta-prism scanning mode without a reference beam correction, (5) non-tilted reference using a second optical head, and (6) alternate switching of data acquisition between the sample and reference beams. With a non-tilted reference method, the measurement accuracy can be improved significantly. Some measurement results are presented. Systematic error in the sample beam arm is not addressed in this paper and should be treated separately.

  1. Comparison of Pyranometers vs. PV Reference Cells for Evaluation of PV Array Performance

    Energy Technology Data Exchange (ETDEWEB)

    Dunn, L.; Gostein, M.; Emery, K.

    2012-09-01

    As the photovoltaics (PV) industry has grown, the need for accurately monitoring the solar resource of PV power plants has increased. Historically, the PV industry has relied on thermopile pyranometers for irradiance measurements, and a large body of historical irradiance data taken with pyranometers exists. However, interest in PV reference devices is increasing. In this paper, we discuss why PV reference devices are better suited for PV applications, and estimate the typical uncertainties in irradiance measurements made with both pyranometers and PV reference devices. We assert that the quantity of interest in monitoring a PV power plant is the equivalent irradiance under the IEC 60904-3 reference solar spectrum that would produce the same electrical response in the PV array as the incident solar radiation. For PV-plant monitoring applications, we find the uncertainties in irradiance measurements of this type to be on the order of +/-5% for thermopile pyranometers and +/-2.4% for PV reference devices.

  2. Development and characterisation of a new line width reference material

    Science.gov (United States)

    Dai, Gaoliang; Zhu, Fan; Heidelmann, Markus; Fritz, Georg; Bayer, Thomas; Kalt, Samuel; Fluegge, Jens

    2015-11-01

    A new critical dimension (CD, often synonymously used for line width) reference material with improved vertical parallel sidewalls (IVPSs) has been developed and characterised. The sample has a size of 6 mm  ×  6 mm, consisting of 4 groups of 5  ×  5 feature patterns. Each feature pattern has a group of five reference line features with a nominal CD of 50 nm, 70 nm, 90 nm, 110 nm and 130 nm, respectively. Each feature pattern includes a pair of triangular alignment marks, applicable for precisely identifying the target measurement position, e.g. for comparison or calibration between different tools. The geometry of line features has been investigated thoroughly using a high-resolution transmission electron microscope and a CD atomic force microscope (CD-AFM). Their results indicate the high quality of the line features: the top corner radius of  strategy for the non-destructive calibration of the developed sample is introduced, which enables the application of the reference material in practice.

  3. Evaluating the adequacy of a reference site pool for ecological assessments in environmentally complex regions

    Science.gov (United States)

    Ode, Peter R.; Rehn, Andrew C.; Mazor, Raphael D.; Schiff, Kenneth C.; Stein, Eric D.; May, Jason; Brown, Larry R.; Herbst, David B.; Gillette, D.D.; Lunde, Kevin; Hawkins, Charles P.

    2016-01-01

    Many advances in the field of bioassessment have focused on approaches for objectively selecting the pool of reference sites used to establish expectations for healthy waterbodies, but little emphasis has been placed on ways to evaluate the suitability of the reference-site pool for its intended applications (e.g., compliance assessment vs ambient monitoring). These evaluations are critical because an inadequately evaluated reference pool may bias assessments in some settings. We present an approach for evaluating the adequacy of a reference-site pool for supporting biotic-index development in environmentally heterogeneous and pervasively altered regions. We followed common approaches for selecting sites with low levels of anthropogenic stress to screen 1985 candidate stream reaches to create a pool of 590 reference sites for assessing the biological integrity of streams in California, USA. We assessed the resulting pool of reference sites against 2 performance criteria. First, we evaluated how well the reference-site pool represented the range of natural gradients present in the entire population of streams as estimated by sites sampled through probabilistic surveys. Second, we evaluated the degree to which we were successful in rejecting sites influenced by anthropogenic stress by comparing biological metric scores at reference sites with the most vs fewest potential sources of stress. Using this approach, we established a reference-site pool with low levels of human-associated stress and broad coverage of environmental heterogeneity. This approach should be widely applicable and customizable to particular regional or programmatic needs.

  4. Python pocket reference, version 2.4

    CERN Document Server

    Lutz, Mark

    2005-01-01

    Python is optimized for quality, productivity, portability, and integration. Hundreds of thousands of Python developers around the world rely on Python for general-purpose tasks, Internet scripting, systems programming, user interfaces, and product customization. Available on all major computing platforms, including commercial versions of Unix, Linux, Windows, and Mac OS X, Python is portable, powerful and remarkable easy to use. With its convenient, quick-reference format, Python Pocket Reference, 3rd Edition is the perfect on-the-job reference. More importantly, it's now been refreshed

  5. Reference and information services an introduction

    CERN Document Server

    Bopp, Richard E

    2011-01-01

    Reflecting the dramatic changes shaped by rapidly developing technologies over the past six years, this new fourth edition of Reference and Information Services takes the introduction to reference sources and services significantly beyond the content of the first three editions. In Part I, Concepts and Processes, chapters have been revised and updated to reflect new ideas and methods in the provision of reference service in an era when many users have access to the Web. In Part II, Information Sources and Their Use, discussion of each source type has been updated to encompass key resources in

  6. Path Generation for High-Performance Motion of ROVs Based on a Reference Model

    Directory of Open Access Journals (Sweden)

    Daniel de A. Fernandes

    2015-04-01

    Full Text Available This paper deals with the generation of sufficiently smooth position, velocity, and acceleration references for guiding the motion of an ROV along purposefully defined curvature-continuous paths in automated missions. The references are meant to be employed in high-performance trajectory tracking and dynamic positioning applications. The path planning problem is not in the scope of this work. A reference model that synthesises references concerning a single Degree-of-Freedom (DoF motion is initially described. Then, the use of the synthesised references as the parametrisation for other references concerning multiple DoF motion along curvature-continuous paths is exploited. Results from computer simulations and full-scale sea trials, both based on the NTNU's ROV Minerva, are presented and discussed.

  7. a Study on Producing Highly Reliabile Reference Data Sets for Global Land Cover Validation

    Science.gov (United States)

    Soyama, N.; Muramatsu, K.; Daigo, M.; Ochiai, F.; Fujiwara, N.

    2016-06-01

    Validating the accuracy of land cover products using a reliable reference dataset is an important task. A reliable reference dataset is produced with information derived from ground truth data. Recently, the amount of ground truth data derived from information collected by volunteers has been increasing globally. The acquisition of volunteer-based reference data demonstrates great potential. However information given by volunteers is limited useful vegetation information to produce a complete reference dataset based on the plant functional type (PFT) with five specialized forest classes. In this study, we examined the availability and applicability of FLUXNET information to produce reference data with higher levels of reliability. FLUXNET information was useful especially for forest classes for interpretation in comparison with the reference dataset using information given by volunteers.

  8. Post-Newtonian reference-ellipsoid for relativistic geodesy

    CERN Document Server

    Kopeikin, Sergei; Mazurova, Elena

    2015-01-01

    We apply general relativity to construct the post-Newtonian background manifold that serves as a reference level surface in relativistic geodesy for conducting calculation of geoid's undulation. We chose the perfect homogeneous fluid uniformly rotating around a fixed axis as a source of the background manifold. We, then, reformulate and extend rotating-fluid calculations done by a number of previous researchers for astrophysical applications to the realm of relativistic geodesy to find out the algebraic equation of the post-Newtonian reference-ellipsoid. We explicitly perform all integrals characterizing gravitational potentials inside the fluid body and represent them in terms of elementary functions depending on the body's eccentricity. We fully explore the coordinate freedom of the equations describing the post-Newtonian ellipsoid and demonstrate that the fractional deviation of the post-Newtonian level surface from the Maclaurin ellipsoid can be made much smaller than the previously anticipated estimate a...

  9. Conditional Reference Adaptation for Offset-free MPC

    DEFF Research Database (Denmark)

    Waschl, Harald; Jørgensen, John Bagterp; Huusom, Jakob Kjøbsted;

    2014-01-01

    Model predictive control has become a widely accepted strategy in industrial applications in the recent years. Often mentioned reasons for the success are the optimization based on a system model, consideration of constraints and an intuitive tuning process. However, as soon as unknown disturbances...... addresses the performance targets in the nominal case, decouples the system and essentially leads to a rst order response. The second outer loop enables oset-free tracking in case of unknown disturbances and consists of feedback controllers adapting the reference. Due to the mentioned properties...... these controllers can be tuned separate and by known guidelines. To address conditions with active input constraints, additionally a conditional reference adaptation scheme is introduced. The tuning strategy is evaluated on a simulated linear Wood-Berry binary distillation column example....

  10. Nationwide Multicenter Reference Interval Study for 28 Common Biochemical Analytes in China.

    Science.gov (United States)

    Xia, Liangyu; Chen, Ming; Liu, Min; Tao, Zhihua; Li, Shijun; Wang, Liang; Cheng, Xinqi; Qin, Xuzhen; Han, Jianhua; Li, Pengchang; Hou, Li'an; Yu, Songlin; Ichihara, Kiyoshi; Qiu, Ling

    2016-03-01

    A nationwide multicenter study was conducted in the China to explore sources of variation of reference values and establish reference intervals for 28 common biochemical analytes, as a part of the International Federation of Clinical Chemistry and Laboratory Medicine, Committee on Reference Intervals and Decision Limits (IFCC/C-RIDL) global study on reference values. A total of 3148 apparently healthy volunteers were recruited in 6 cities covering a wide area in China. Blood samples were tested in 2 central laboratories using Beckman Coulter AU5800 chemistry analyzers. Certified reference materials and value-assigned serum panel were used for standardization of test results. Multiple regression analysis was performed to explore sources of variation. Need for partition of reference intervals was evaluated based on 3-level nested ANOVA. After secondary exclusion using the latent abnormal values exclusion method, reference intervals were derived by a parametric method using the modified Box-Cox formula. Test results of 20 analytes were made traceable to reference measurement procedures. By the ANOVA, significant sex-related and age-related differences were observed in 12 and 12 analytes, respectively. A small regional difference was observed in the results for albumin, glucose, and sodium. Multiple regression analysis revealed BMI-related changes in results of 9 analytes for man and 6 for woman. Reference intervals of 28 analytes were computed with 17 analytes partitioned by sex and/or age. In conclusion, reference intervals of 28 common chemistry analytes applicable to Chinese Han population were established by use of the latest methodology. Reference intervals of 20 analytes traceable to reference measurement procedures can be used as common reference intervals, whereas others can be used as the assay system-specific reference intervals in China.

  11. Overview of Uranium Isotopic Reference Materials at IRMM

    Science.gov (United States)

    Alonso-Munoz, A.; Richter, S.; Eykens, R.; Aregbe, Y.; Kuehn, H.; Verbruggen, A.

    2007-12-01

    For many applications in the geological sciences, in particular in geochemistry research, isotope ratio measurements play a significant role. For instance, in geochronology isotope abundances of uranium and its daughter products thorium and lead have been used since more than five decades to determine the age of various samples of geological interest. However, in order to validate mass spectrometric measurement procedures and to calibrate detector systems, suitable isotope reference materials are needed. IRMM is a well recognized provider for nuclear isotope reference materials to the nuclear industry and nuclear safeguards authorities, which can also be used for geological applications. This paper gives an overview of isotope reference materials for uranium prepared and certified at IRMM. These materials are synthetic isotope reference materials prepared based on proven methods of purifying and mixing highly enriched oxides. Firstly, a set of 10 mixtures of 233U, 235U and 238U was made in which the 235U/238U ratios were kept at 1:1 and the 233U/235U ratios varied from 1.0 to 10-6 (IRMM-072). This set is ideal for checking the linearity response of detectors used in isotope mass spectrometry. Recently, after the IRMM-072 series was exhausted, it has been replaced by the IRMM-073 and IRMM-074 series. Secondly the double spike IRMM-3636 with a 233U/236U ratio of 1:1 was prepared which allows internal mass fractionation correction for high precision 235U/238U ratio measurements. The 234U abundance of this double spike material is low enough to allow an accurate and precise correction of 234U/238U ratios, even for measurements of close to equilibrium uranium samples.

  12. National Drug File - Reference Terminology API

    Data.gov (United States)

    U.S. Department of Health & Human Services — The National Drug File - Reference Terminology (NDF-RT) is produced by the U.S. Department of Veterans Affairs, Veterans Health Administration (VHA). NDF-RT is an...

  13. Genetics Home Reference: critical congenital heart disease

    Science.gov (United States)

    ... Health Conditions critical congenital heart disease critical congenital heart disease Enable Javascript to view the expand/collapse boxes. ... PDF Open All Close All Description Critical congenital heart disease (CCHD) is a term that refers to a ...

  14. Climate Reference Network Hourly02 Product

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The U.S. Climate Reference Network is designed specifically to monitor national climate change with best scientific practice and adherence to the accepted principles...

  15. Connecting VLBI and Gaia celestial reference frames

    CERN Document Server

    Malkin, Zinovy

    2016-01-01

    The current state of the link problem between radio and optical celestial reference frames is considered. The main objectives of the investigations in this direction during the next few years are the preparation of a comparison and the mutual orientation and rotation between the optical {\\it Gaia} Celestial Reference Frame (GCRF) and the 3rd generation radio International Celestial Reference Frame (ICRF3), obtained from VLBI observations. Both systems, ideally, should be a realization of the ICRS (International Celestial Reference System) at micro-arcsecond level accuracy. Therefore, the link accuracy between the ICRF and GCRF should be obtained with similar error level, which is not a trivial task due to relatively large systematic and random errors in source positions at different frequency bands. In this paper, a brief overview of recent work on the GCRF--ICRF link is presented. Additional possibilities to improve the GCRF--ICRF link accuracy are discussed. The suggestion is made to use astrometric radio s...

  16. Genetics Home Reference: juvenile idiopathic arthritis

    Science.gov (United States)

    ... Home Health Conditions juvenile idiopathic arthritis juvenile idiopathic arthritis Enable Javascript to view the expand/collapse boxes. ... PDF Open All Close All Description Juvenile idiopathic arthritis refers to a group of conditions involving joint ...

  17. Registration document 2005; Document de reference 2005

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-07-01

    This reference document of Gaz de France provides information and data on the Group activities in 2005: financial informations, business, activities, equipments factories and real estate, trade, capital, organization charts, employment, contracts and research programs. (A.L.B.)

  18. Medicare Referring Provider (DMEPOS) Data CY2013

    Data.gov (United States)

    U.S. Department of Health & Human Services — The Centers for Medicare and Medicaid Services (CMS) released a new dataset, the Referring Provider Durable Medical Equipment, Prosthetics, Orthotics and Supplies...

  19. Visual performance fields: frames of reference.

    Science.gov (United States)

    Corbett, Jennifer E; Carrasco, Marisa

    2011-01-01

    Performance in most visual discrimination tasks is better along the horizontal than the vertical meridian (Horizontal-Vertical Anisotropy, HVA), and along the lower than the upper vertical meridian (Vertical Meridian Asymmetry, VMA), with intermediate performance at intercardinal locations. As these inhomogeneities are prevalent throughout visual tasks, it is important to understand the perceptual consequences of dissociating spatial reference frames. In all studies of performance fields so far, allocentric environmental references and egocentric observer reference frames were aligned. Here we quantified the effects of manipulating head-centric and retinotopic coordinates on the shape of visual performance fields. When observers viewed briefly presented radial arrays of Gabors and discriminated the tilt of a target relative to homogeneously oriented distractors, performance fields shifted with head tilt (Experiment 1), and fixation (Experiment 2). These results show that performance fields shift in-line with egocentric referents, corresponding to the retinal location of the stimulus.

  20. Genetics Home Reference: giant axonal neuropathy

    Science.gov (United States)

    ... R. Proteomic analysis in giant axonal neuropathy: new insights into disease mechanisms. Muscle Nerve. 2012 Aug;46( ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  1. Genetics Home Reference: Bardet-Biedl syndrome

    Science.gov (United States)

    ... Citation on PubMed Zaghloul NA, Katsanis N. Mechanistic insights into Bardet-Biedl syndrome, a model ciliopathy. J ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  2. Genetics Home Reference: Bart-Pumphrey syndrome

    Science.gov (United States)

    ... of connexins in ear and skin physiology - functional insights from disease-associated mutations. Biochim Biophys Acta. 2013 ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  3. Genetics Home Reference: fragile X syndrome

    Science.gov (United States)

    ... Van Esch H. The Fragile X premutation: new insights and clinical consequences. Eur J Med Genet. 2006 ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  4. Genetics Home Reference: atelosteogenesis type 1

    Science.gov (United States)

    ... affinity in the absence of major structural disturbance: Insights from the crystal structures of filamin B actin ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  5. Genetics Home Reference: type 1 diabetes

    Science.gov (United States)

    ... or Free article on PubMed Central Morahan G. Insights into type 1 diabetes provided by genetic analyses. ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  6. Genetics Home Reference: progressive external ophthalmoplegia

    Science.gov (United States)

    ... JD, Copeland WC. Mitochondrial DNA replication and disease: insights from DNA polymerase γ mutations. Cell Mol Life ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  7. Genetics Home Reference: polycystic kidney disease

    Science.gov (United States)

    ... ED. Pathophysiology of childhood polycystic kidney diseases: new insights into disease-specific therapy. Pediatr Res. 2014 Jan; ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  8. Genetics Home Reference: Brooke-Spiegler syndrome

    Science.gov (United States)

    ... gene (CYLD) mutations in Brooke-Spiegler syndrome: novel insights into the role of deubiquitination in cell signaling. ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  9. Genetics Home Reference: arrhythmogenic right ventricular cardiomyopathy

    Science.gov (United States)

    ... with arrhythmogenic right ventricular dysplasia/cardiomyopathy provides novel insights into patterns of disease expression. Circulation. 2007 Apr ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  10. Genetics Home Reference: Pelizaeus-Merzbacher disease

    Science.gov (United States)

    ... Garbern JY. Pelizaeus-Merzbacher disease: pathogenic mechanisms and insights into the roles of proteolipid protein 1 in ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  11. Genetics Home Reference: atelosteogenesis type 3

    Science.gov (United States)

    ... affinity in the absence of major structural disturbance: Insights from the crystal structures of filamin B actin ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  12. Genetics Home Reference: familial hypertrophic cardiomyopathy

    Science.gov (United States)

    ... PubMed Ho CY. New Paradigms in Hypertrophic Cardiomyopathy: Insights from Genetics. Prog Pediatr Cardiol. 2011 May;31( ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  13. Genetics Home Reference: childhood myocerebrohepatopathy spectrum

    Science.gov (United States)

    ... JD, Copeland WC. Mitochondrial DNA replication and disease: insights from DNA polymerase γ mutations. Cell Mol Life ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  14. Genetics Home Reference: primary carnitine deficiency

    Science.gov (United States)

    ... Majdalani M. Primary carnitine deficiency: novel mutations and insights into the cardiac phenotype. Clin Genet. 2014 Feb; ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  15. Genetics Home Reference: spondylocarpotarsal synostosis syndrome

    Science.gov (United States)

    ... affinity in the absence of major structural disturbance: Insights from the crystal structures of filamin B actin ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  16. Genetics Home Reference: familial restrictive cardiomyopathy

    Science.gov (United States)

    ... AV. Malignant and benign mutations in familial cardiomyopathies: insights into mutations linked to complex cardiovascular phenotypes. J ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  17. Genetics Home Reference: fragile XE syndrome

    Science.gov (United States)

    ... AFF (AF4/FMR2) family of RNA-binding proteins: insights into the molecular pathology of FRAXE intellectual disability. ... healthcare professional . About Genetics Home Reference Site Map Customer Support Selection Criteria for Links USA.gov Copyright ...

  18. Source Reference File Usage: Management Summary

    Data.gov (United States)

    Social Security Administration — A report by region then by state that details how often medical sources from the Source Reference File are used when taking disability claims vs. sources that are...

  19. Selected Reference Books of 2000/2001.

    Science.gov (United States)

    McIlvaine, Eileen

    2002-01-01

    Presents an annotated list of selected recent scholarly and general reference works under the subject categories of archives; literature; music; psychology; sociology; black studies; women's studies; history and area studies; and new editions and supplements. (LRW)

  20. Astronomical catalog desk reference, 1994 edition

    Science.gov (United States)

    1994-01-01

    The Astronomical Catalog Desk Reference is designed to aid astronomers in locating machine readable catalogs in the Astronomical Data Center (ADC) archives. The key reference components of this document are as follows: A listing of shortened titles for all catalogs available from the ADC (includes the name of the lead author and year of publication), brief descriptions of over 300 astronomical catalogs, an index of ADC catalog numbers by subject keyword, and an index of ADC catalog numbers by author. The heart of this document is the set of brief descriptions generated by the ADC staff. The 1994 edition of the Astronomical Catalog Desk Reference contains descriptions for over one third of the catalogs in the ADC archives. Readers are encouraged to refer to this section for concise summaries of those catalogs and their contents.

  1. Global Reference Tables for Management Information Systems.

    Data.gov (United States)

    Social Security Administration — This database is a collection of reference tables that store common information used throughout SSA. These tables standardize code structures and code usage of SSA...

  2. Selected Reference Books of 1997-98.

    Science.gov (United States)

    McIlvaine, Eileen

    1998-01-01

    Presents an annotated selection of recent scholarly and general reference works under the subject headings of religion and mythology, literature, architecture, dance, film and television, women's studies, political science, and history, as well as new editions and supplements. (LRW)

  3. Global Reference Tables for Production Systems.

    Data.gov (United States)

    Social Security Administration — This database is a collection of reference tables that store common information used throughout SSA. These tables standardized code structures and code usage of SSA...

  4. Marine Mammal Food Habits Reference Collections

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The National Marine Mammal Laboratory (NMML) Food Habits Reference Collection, containing over 8000 specimens of cephalopod beaks and fish bones and otoliths, is...

  5. Printed circuit board designer's reference basics

    CERN Document Server

    Robertson, Chris

    2003-01-01

    PCB design instruction and reference manual, all in one book, with in- depth explanation of the processes and tools used in modern PCB design Standards, formulas, definitions, and procedures, plus software to tie it all together.

  6. Solid Reference Electrode of Metallurgical Oxygen Sensor

    Institute of Scientific and Technical Information of China (English)

    LOU Tian-jun; KONG Xiang-hua; HUANG Ke-qin; LIU Qing-guo

    2006-01-01

    The thermal equilibrium state of the reference electrode was investigated. The results show that the temperature difference between the inside and the outside of zirconia tube was very small and the Seebeck effect can be ignored after the sensor was dipped into liquid steel for more than 2 s. A special sensor was designed to test the relation between the EMF (electromotive force) of sensor and the thermal equilibrium state of the reference electrode. Based on these results, it is suggested that the peak in EMF curve was caused by the change of oxygen potential in reference electrode before the thermal equilibrium was reached. If NiO was added by 2%-5% to the Cr/Cr2O3 reference electrode, the peak in EMF curve could be eliminated.

  7. Climate Reference Network Daily01 Product

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — The U.S. Climate Reference Network is designed specifically to monitor national climate change with best scientific practice and adherence to the accepted principles...

  8. 40 CFR 1065.1010 - Reference materials.

    Science.gov (United States)

    2010-07-01

    ... and Technology that we have incorporated by reference. The first column lists the number and name of... Procedures,” Amended July 30, 2002, Mobile Source Division, California Air Resources Board 1065.805...

  9. Assessing clustering results with reference taxonomies.

    Science.gov (United States)

    Valiente, Gabriel

    2006-01-01

    The comparative analysis of phylogenies obtained using different phylogenetic methods or different gene sequences for a given set of species, is usually done by computing some quantitative measure of similarity between the phylogenetic trees. Such a quantitative approach provides little insight into the actual similarities and differences between the alternative phylogenies. In this paper, we present a method for the qualitative assessment of a phylogenetic tree against a reference taxonomy, based on highlighting their common clusters. Our algorithms build a reference taxonomy for the taxa present in a given phylogenetic tree and produce a dendogram for the input phylogenetic tree, with branches in those clusters common to the reference taxonomy highlighted. Our implementation of the algorithms produces publication-quality graphics. For unrooted phylogenies, the method produces a radial cladogram for the input phylogenetic tree, with branches in common clusters to the reference taxonomy highlighted.

  10. References in the Australasian Medical Journal

    Directory of Open Access Journals (Sweden)

    Prakash Adhikari

    2010-12-01

    Full Text Available BackgroundReferences serve as an important tool in providing credibility to the published literature and to assist retrieval of the cited and related information. This study was done to observe the accuracy of references in articles published in Australasian Medical Journal.Method Fifty references were randomly selected from two different issues of Australasian Medical Journal (AMJ: Volume 3, Number 11, 2010 and Volume 3, Number 10, 2010. The instructions for authors of this journal were examined. References from each article were compared with the original for accuracy, using the following six elements: 1 authors; including spelling, initials, order and number; 2 title, including spelling and punctuation; 3 journal name, including use of correct abbreviation as listed in Index Medicus; 4 year; 5 volume; and 6 page numbers, including first and last page numbers. Citations were considered incorrect if there was an error in any of these six elements. References not cited from indexed journals were excluded. Statistical analysis was done by using frequency and percentage.ResultsResults show that 14.0% references in AMJ were inaccurate. Most common errors were author’s name and journal name. Author’s names were found to be incorrect in 10.0% references while journal name (either incorrect abbreviations or incorrect instructions or punctuation errors were found to be incorrect in 4.0%. Least common error was found in writing the title of the article (2.0%. There were no errors found in other elements.ConclusionErrors in citing the references are also found in the AMJ. The quoted error in this study (14.0% is comparable to other international literature. The majority of errors are avoidable. So, the authors, editors and the reviewers have to check for any errors seriously before publication in the journal.

  11. The evolution of electronic reference sources

    OpenAIRE

    Van Epps, Amy S.

    2004-01-01

    Purpose To provide a historical look at the development of web versions of reference materials and discuss what makes an easy-to-use and useful electronic handbook. Design/methodology/approach Electronic reference materials were limited to handbooks available on the web. Observations and assumptions about usability are tested with an information retrieval test for specific tasks in print and online editions of the same texts. Findings Recommended adoption of those elements which create a w...

  12. Review of Epigenetics: A Reference Manual

    OpenAIRE

    Banister, Carolyn E

    2012-01-01

    The study of epigenetics has experienced exponential growth in the past 15 years and continues to be a major focus of study across biological disciplines. A new reference text Epigenetics: A Reference Manual, published by Caister Academic Press and edited by Jeffrey M. Craig and Nicholas C. Wong (Developmental Epigenetics Group, Murdoch Children's Research Institute, Victoria, Australia), presents a current and comprehensive look into the many facets of epigenetics research. The information t...

  13. Reference Sources and Services in the Humanities

    OpenAIRE

    1996-01-01

    The paper is to discuss the meaning, the nature, and the subject fields of the Humanities; to study the information needs of the Humanists; and to introduce some important reference sources in the Humanities.The paper indicates the future trends of reference services in the Humanities are as follows : to develop on-line searching, to collect various kinds library materials, to educate and train specialized librarians on Humanities, as well as to march towards virtual library era in networking...

  14. Analysis of SOFCs Using Reference Electrodes

    Energy Technology Data Exchange (ETDEWEB)

    Finklea, H.; Chen, X.; Gerdes, K.; Pakalapati, S.; Celik, I.

    2013-01-01

    Reference electrodes are frequently applied to isolate the performance of one electrode in a solid oxide fuel cell. However, reference electrode simulations raise doubt to veracity of data collected using reference electrodes. The simulations predict that the reported performance for the one electrode will frequently contain performance of both electrodes. Nonetheless, recent reports persistently treat data so collected as ideally isolated. This work confirms the predictions of the reference electrode simulations on two SOFC designs, and to provides a method of validating the data measured in the 3-electrode configuration. Validation is based on the assumption that a change in gas composition to one electrode does not affect the impedance of the other electrode at open circuit voltage. This assumption is supported by a full physics simulation of the SOFC. Three configurations of reference electrode and cell design are experimentally examined using various gas flows and two temperatures. Impedance data are subjected to deconvolution analysis and equivalent circuit fitting and approximate polarization resistances of the cathode and anode are determined. The results demonstrate that the utility of reference electrodes is limited and often wholly inappropriate. Reported impedances and single electrode polarization values must be scrutinized on this basis.

  15. Dynamics of a Quantum Reference Frame

    CERN Document Server

    Poulin, D; Poulin, David; Yard, Jon

    2006-01-01

    We analyze a quantum mechanical gyroscope, which is modeled as a large spin and used as a reference against which to measure the angular momenta of spin-1/2 particles. These measurements induce a back-action on the reference which is the central focus of our study. We begin by deriving explicit expressions for the quantum channel representing the back-action. Then, we analyze the dynamics incurred by the reference when it is used to sequentially measure particles drawn from a fixed ensemble. We prove that the reference thermalizes with the measured particles and find that generically, the thermal state is reached in time which scales linearly with the size of the reference. This contrasts a recent conclusion of Bartlett et al. that this takes a quadratic amount of time when the particles are completely unpolarized. We now understand their result in terms of a simple physical principle based on symmetries and conservation laws. Finally, we initiate the study of the non-equilibrium dynamics of the reference. He...

  16. The International Reference Ionosphere: Model Update 2016

    Science.gov (United States)

    Bilitza, Dieter; Altadill, David; Reinisch, Bodo; Galkin, Ivan; Shubin, Valentin; Truhlik, Vladimir

    2016-04-01

    The International Reference Ionosphere (IRI) is recognized as the official standard for the ionosphere (COSPAR, URSI, ISO) and is widely used for a multitude of different applications as evidenced by the many papers in science and engineering journals that acknowledge the use of IRI (e.g., about 11% of all Radio Science papers each year). One of the shortcomings of the model has been the dependence of the F2 peak height modeling on the propagation factor M(3000)F2. With the 2016 version of IRI, two new models will be introduced for hmF2 that were developed directly based on hmF2 measurements by ionosondes [Altadill et al., 2013] and by COSMIC radio occultation [Shubin, 2015], respectively. In addition IRI-2016 will include an improved representation of the ionosphere during the very low solar activities that were reached during the last solar minimum in 2008/2009. This presentation will review these and other improvements that are being implemented with the 2016 version of the IRI model. We will also discuss recent IRI workshops and their findings and results. One of the most exciting new projects is the development of the Real-Time IRI [Galkin et al., 2012]. We will discuss the current status and plans for the future. Altadill, D., S. Magdaleno, J.M. Torta, E. Blanch (2013), Global empirical models of the density peak height and of the equivalent scale height for quiet conditions, Advances in Space Research 52, 1756-1769, doi:10.1016/j.asr.2012.11.018. Galkin, I.A., B.W. Reinisch, X. Huang, and D. Bilitza (2012), Assimilation of GIRO Data into a Real-Time IRI, Radio Science, 47, RS0L07, doi:10.1029/2011RS004952. Shubin V.N. (2015), Global median model of the F2-layer peak height based on ionospheric radio-occultation and ground-based Digisonde observations, Advances in Space Research 56, 916-928, doi:10.1016/j.asr.2015.05.029.

  17. Myths of Isotopic Reference Materials Busted

    Science.gov (United States)

    Coplen, T.

    2007-12-01

    During the past several years, the determination of the isotopic abundances of elements including H, Li, B, C, N, O, Mg, Si, S, Cl, Ca, Cr, Fe, Cu, Zn, Tl, and Se has substantially increased because of expanded use in hydrology, environmental studies, microbiology, forensic investigations, atmospheric investigations, oceanography, etc. Improvements in instrumentation enable increasingly precise isotope-amount-ratio measurements in these fields, but these improvements in precision commonly do not lead to improvements in accuracy because of the lack or improper use of isotopic reference materials. When properly used, these critically important materials enable any laboratory worldwide to measure the same homogeneous sample and report the same isotopic abundance within analytical uncertainty. For example, for stable isotopic analysis of gaseous hydrogen samples, the agreement among 36 laboratories worldwide before normalization to any hydrogen gas reference material was 11.8 per mill. After normalization to anchors (gaseous H isotopic reference materials) at each end of the delta H-2 scale, the agreement was 0.85 per mill, an improvement of more than an order of magnitude. Consistency of delta C-13 measurements often can be improved by nearly 50 percent by anchoring the delta C-13 scale with two isotopic reference materials differing substantially in C-13 mole fraction, namely NBS 19 calcite and L-SVEC lithium carbonate. Agreement of delta C-13 values of four expert laboratories analyzing USGS40 L- glutamic acid by CF-IRMS methods improved from 0.084 to 0.015 per mill with use of the two scale anchors (NBS 19 and L-SVEC). Solid oxygen isotopic reference materials (IAEA-600 caffeine, IAEA-601 and IAEA-602 benzoic acids, IAEA-NO-3, USGS32, USGS34, and USGS35 nitrates, NBS-127, IAEA-SO-5, and IAEA-SO-6 barium sulfates) are poorly calibrated. Calibrating these solids to the VSMOW-SLAP reference water scale has been very difficult because both the solids and reference

  18. Nuclear thermal rocket workshop reference system Rover/NERVA

    Science.gov (United States)

    Borowski, Stanley K.

    1991-01-01

    The Rover/NERVA engine system is to be used as a reference, against which each of the other concepts presented in the workshop will be compared. The following topics are reviewed: the operational characteristics of the nuclear thermal rocket (NTR); the accomplishments of the Rover/NERVA programs; and performance characteristics of the NERVA-type systems for both Mars and lunar mission applications. Also, the issues of ground testing, NTR safety, NASA's nuclear propulsion project plans, and NTR development cost estimates are briefly discussed.

  19. PMP Certification All-In-One Desk Reference For Dummies

    CERN Document Server

    Stackpole, Cynthia Snyder

    2011-01-01

    Be as prepared as possible to take the PMP certification exam The PMP certification is the most popular project management certification available, but also a very difficult certification to obtain with very demanding requirements. That's where this All-in-One reference comes in. Packed with valuable information for taking the exam, the nine books in one covers everything from the certification process to gathering information for the application and signing up to take the exam, as well as studying for the most pertinent parts of the Project Management Body of Knowledge (PMBOK), and review que

  20. Easy-to-use strategy for reference gene selection in quantitative real-time PCR experiments.

    Science.gov (United States)

    Klenke, Stefanie; Renckhoff, Kristina; Engler, Andrea; Peters, Jürgen; Frey, Ulrich H

    2016-12-01

    Real-time PCR is an indispensable technique for mRNA expression analysis but conclusions depend on appropriate reference gene selection. However, while reference gene selection has been a topic of publications, this issue is often disregarded when measuring target mRNA expression. Therefore, we (1) evaluated the frequency of appropriate reference gene selection, (2) suggest an easy-to-use tool for least variability reference gene selection, (3) demonstrate application of this tool, and (4) show effects on target gene expression profiles. All 2015 published articles in Naunyn-Schmiedeberg's Archives of Pharmacology were screened for the use of quantitative real-time PCR analysis and selection of reference genes. Target gene expression (Vegfa, Grk2, Sirt4, and Timp3) in H9c2 cells was analyzed following various interventions (hypoxia, hyperglycemia, and/or isoflurane exposure with and without subsequent hypoxia) in relation to putative reference genes (Actb, Gapdh, B2m, Sdha, and Rplp1) using the least variability method vs. an arbitrarily selected but established reference gene. In the vast majority (18 of 21) of papers, no information was provided regarding selection of an appropriate reference gene. In only 1 of 21 papers, a method of appropriate reference gene selection was described and in 2 papers reference gene selection remains unclear. The method of reference gene selection had major impact on interpretation of target gene expression. With hypoxia, for instance, the least variability gene was Rplp1 and target gene expression (Vefga) heavily showed a 2-fold up-regulation (p = 0.022) but no change (p = 0.3) when arbitrarily using Gapdh. Frequency of appropriate reference gene selection in this journal is low, and we propose our strategy for reference gene selection as an easy tool for proper target gene expression.