WorldWideScience

Sample records for application central cafeteria

  1. From Cafeteria to Cafe.

    Science.gov (United States)

    Harrington-Lueker, Donna

    1992-01-01

    If school architects, cafeteria designers, and some food service personnel have their way, the long, grey serving line characterizing most school cafeterias will go the way of meatloaf and mashed potatoes. This means booths and restaurant-like tables, school colors, brightly lit menu boards, windows overlooking courtyards, and mall-like…

  2. Summer season | Cafeteria closures

    CERN Multimedia

    2013-01-01

    Please note the following cafeteria closures over the summer season: Bldg. 54 closed from 29/07/2013 to 06/09/2013. Bldg. 13: closed from 13/07/2013 to 06/09/2013. Restaurant No. 2, table service (brasserie and restaurant): closed from 01/08/2013 to 06/09/2013. Bldg. 864: closed from 29/07/2013 to 06/09/2013. Bldg. 865: closed from 29/07/2013 to 06/09/2013.

  3. Smartphone app allows online payments in cafeterias on Meyrin site

    CERN Multimedia

    2016-01-01

    As of October 18, 2016, Novae will implement a new additional system of payment in all the cafeterias on the Meyrin site, using the smartphone application Mobino. For step-by-step instructions watch this short video:

  4. Cafeteria/Multi-Purpose Spaces.

    Science.gov (United States)

    Larsen, Christopher W.

    2001-01-01

    Highlights school cafeteria design criteria that creates dining facilities that are both social areas as well as eating spaces. Also examined are key design considerations for multi-purpose areas. (GR)

  5. School Cafeteria Operations: Separating Myth from Reality

    Science.gov (United States)

    Weeks, Richard

    2011-01-01

    School officials often assume that the food service director or management company should be the one concerned with the cafeteria program's management details. But of course that's not the case. Cafeteria operations affect the school business bottom line, so they indeed fall under the purview of school business officials. Not only should school…

  6. Microbiological criteria in public catering: sampling and auditing experiences in canteens and cafeterias in Piedmont

    Directory of Open Access Journals (Sweden)

    Amaranta Traversa

    2013-02-01

    Full Text Available In the period 2006-2011 six public catering establishments (3 canteens and 3 cafeterias were monitored, trough audit and sampling, in order to verify the application of good manufacturing and hygiene practices during food production, handling and serving. The compliance to microbiological food safety criteria (Listeria monocytogenes and Salmonella spp. and process hygiene criteria were investigated using ISO standards for microbiological analyses. A total of 612 samples were collected: 192 food samples and 288 environmental swab samples from canteens; 33 food samples and 99 swab samples from cafeterias. Regarding food safety, two samples were in disagreement with criteria fixed in EU Regulation as Listeria monocytogenes was isolated from a turkey breast in a canteen and from a sandwich in a cafeteria. Regarding process hygiene criteria, as no microbiological limits are legally defined for catering services, for this study limits were fixed according to the quality standards of tender, scientific literature and laboratory experience. 23.4% foodstuffs and 8.7% swabs resulted non-compliant in canteens; 48.5% foodstuffs and 6.1% swabs resulted non-compliant in cafeterias. The count of coagulase-positive staphylococci (CPS was higher of the fixed limits in raw turkey meat and in cooked spinach: the presence among CPS of S. aureus was confirmed, strains were not able to produce enterotoxins. The most common non-compliance in hygiene criteria was represented by aerobic colony count (60.7% of total non-compliance in canteens and 75.0% in cafeterias and coliform bacteria (20.3% in canteens and 25.0% in cafeterias. Nine raw foods or raw readyto- eat food samples were non-compliant for both coliform bacteria and aerobic count; one sample (raw turkey meat was non-compliant for CPS and aerobic count but resulted to be compliant after cooking. Auditing and sampling are the most effective tools to improve food quality standard and to enhance food business

  7. Application of Cafeteria Total Rewards in the Incentive of Professional Managers In Ruraf Financial System%自助式整体薪酬在农信系统职业经理人激励中的应用

    Institute of Scientific and Technical Information of China (English)

    栾凌雁; 陈锦新

    2012-01-01

    According to the problems in the incentive of professional managers in rural financial system as well as the characteristics of the professional managers themselves, the characteristics and advantages of cafeteria total rewards in the incentive of professional managers were studied, based on which the practical implementation and issues we should pay attention to of the cafeteria total rewards were brifely analyzed.%从现行农信系统职业经理人激励中存在的问题入手,结合职业经理人自身的特点,对自助式整体薪酬在职业经理人激励中的特点和优点进行了研究,在此基础上,对自助式整体薪酬的具体实施和应注意的问题进行了简要分析.

  8. Bye Bye Cafeteria, Hello Restaurant-Style Dining.

    Science.gov (United States)

    Milshtein, Amy

    1999-01-01

    Examines how the university cafeteria is being transformed into restaurant-style dining to attract and retain sophisticated student customers. Harvard's and Seattle Pacific University's dining facilities are briefly highlighted. Concluding comments address planning tips for converting the old cafeteria into a better dining experience. (GR)

  9. Application of the Balanced Score Card in the Management of Cafeterias of College%浅谈平衡计分卡在高校食堂管理中的运用

    Institute of Scientific and Technical Information of China (English)

    王兴伯

    2014-01-01

    The balanced score card is a kind of efficient instrument for the performance evaluation. More and more for-profit ventures use the balanced score cards to improve the management level of the ventures. With the economic development, the socialized reform of the university logistics gradually changes into operating. Cafeterias management changes into the enterprise model, but it still keeps the characteristic of service first. So, the non-financial indicator is particularly important. This paper introduces the balanced score card as the new way to evaluate the performance of the cafeterias management in college, establishes a comprehensive evaluation index system and analyzes the problems should pay attention to in the construction of the cafeterias management of college to ensure the profit targets on the basis of the high quality service.%平衡计分卡是绩效考核的一种有效工具,越来越多的营利性企业青睐于使用平衡计分卡提高企业管理水平。随着经济发展,高校后勤的社会化改革逐渐向经营性转变,食堂经营向企业模式转变,但依然保持服务性第一的特点,非财务指标显得尤为重要。文章引入平衡计分卡作为高校食堂绩效考核的新途径,建立综合评价指标体系,并分析在高校食堂管理中实施需要注意的问题,以达成高校食堂总愿景,即在保证优质服务的基础上完成营利目标。

  10. [Promotion of healthy eating habits by schools: a methodological proposal for training courses for educators and school cafeteria owners].

    Science.gov (United States)

    Schmitz, Bethsáida de Abreu Soares; Recine, Elisabetta; Cardoso, Gabriela Tavares; da Silva, Juliana Rezende Melo; Amorim, Nina Flávia de Almeida; Bernardon, Renata; Rodrigues, Maria de Lourdes Carlos Ferreirinha

    2008-01-01

    The project entitled Promotion of Health Eating Habits by Schools, operating in the Federal District of Brazil since 2001, encourages good eating habits in the school community within the context of promoting healthy lifestyles and preventing chronic non-communicable diseases. The current article presents and analyzes a methodology to train preschool and elementary educators and school cafeteria owners. The workshops included theoretical classes, practical activities, and educational games and were evaluated on the basis of expansion and applicability of knowledge, in addition to implementation of the 10 steps to a healthy school cafeteria. The proposed pedagogical activities were verified by an analysis of the teachers' workshop folders. The overall evaluation was positive, with expansion of knowledge (p < 0.05) among participants for the three workshop modules. The objectives laid out in the workshop folders were reached by 44% of the teachers. In the implementation of the healthy cafeteria, positive results were observed when comparing the pre and post-training periods. The methodology helped expand knowledge for both teachers and cafeteria owners, highlighting the school community as a prime space for promoting healthy eating. PMID:18670711

  11. Cafeteria-Style Grading in General Chemistry

    Science.gov (United States)

    Goodwin, John A.; Gilbert, Brian D.

    2001-04-01

    Self-selected individual course-grade weighting schemes allow students personal choice of course components in the general chemistry sequence at Coastal Carolina University. With the availability of a wide range of commercial and academically produced pedagogical resources, students can select materials that best suit their own learning styles, social situations, and motivation level. Our students use a signed contract to indicate their preferred grade-weighting schemes for determination of the course grade. In doing so, they choose from course components that include peer-led team learning (PLTL) in the Workshop Chemistry (WSC) model, computer-assisted instruction (CAI) using the ChemSkill Builder (CSB) software, a variety of in-class quizzes and group problem-solving exercises, written exams, and the final written exam. Minimum percentage values are required of all components except WSC and CSB, which have been completely optional graded course components at CCU since the summer of 1999. Comparison of student success in the course and content learning suggests that the improvements observed with introduction of a gamut of activities increase even more when the cafeteria-style grading is implemented.

  12. Serving Up Change in School Cafeterias (with Related Video)

    Science.gov (United States)

    Capalbo, Mike A.

    2011-01-01

    Today's education institution kitchens are colorful and inviting, designed with curvature and stainless steel to compete with local restaurants, offering more variety and efficiency to the demanding health-conscious "Generation Me" consumer who is short on time and big on selection. In short, campus eateries are less "cafeteria" and more "cafe."…

  13. Environmental enrichment and cafeteria diet attenuate the response to chronic variable stress in rats.

    Science.gov (United States)

    Zeeni, N; Bassil, M; Fromentin, G; Chaumontet, C; Darcel, N; Tome, D; Daher, C F

    2015-02-01

    Exposure to an enriched environment (EE) or the intake of a highly palatable diet may reduce the response to chronic stress in rodents. To further explore the relationships between EE, dietary intake and stress, male Sprague-Dawley rats were fed one of two diets for 5 weeks: high carbohydrate (HC) or "cafeteria" (CAF) (Standard HC plus a choice of highly palatable cafeteria foods: chocolate, biscuits, and peanut butter). In addition, they were either housed in empty cages or cages with EE. After the first two weeks, half of the animals from each group were stressed daily using a chronic variable stress (CVS) paradigm, while the other half were kept undisturbed. Rats were sacrificed at the end of the 5-week period. The effects of stress, enrichment and dietary intake on animal adiposity, serum lipids, and stress hormones were analyzed. Results showed an increase in intra-abdominal fat associated with the CAF diet and an increase in body weight gain associated with both the CAF diet and EE. Furthermore, the increase in ACTH associated with CVS was attenuated in the presence of EE and the CAF diet independently while the stress-induced increase in corticosterone was reduced by the combination of EE and CAF feeding. The present study provides evidence that the availability of a positive environment combined to a highly palatable diet increases resilience to the effects of CVS in rats. These results highlight the important place of palatable food and supportive environments in reducing central stress responses.

  14. Pollution Prevention Opportunity Assessment for the SNL/NM cafeterias.

    Energy Technology Data Exchange (ETDEWEB)

    McCord, Samuel Adam

    2005-12-01

    This Pollution Prevention Opportunity Assessment (PPOA) was conducted for the two Sandia National Laboratories/New Mexico cafeteria facilities between May and August 2005. The primary purpose of this PPOA is to assess waste and resource reduction opportunities and issue Pollution Prevention (P2) recommendations for Sandia's food service facilities. This PPOA contains recommendations for energy, water and resource reduction, as well as material substitution based upon environmentally preferable purchasing. Division 3000 has requested the PPOA report as part of the Division's compliance effort to implement the Environmental Management System (EMS) per DOE Order 450.1. This report contains a summary of the information collected and analyses performed with recommended options for implementation. The SNL/NM P2 Group will work with Division 3000 and the respective cafeteria facilities to implement these options.

  15. Ergonomic assessments of three Idaho National Engineering Laboratory cafeterias

    Energy Technology Data Exchange (ETDEWEB)

    Ostrom, L.T.; Romero, H.A.; Gilbert, B.G.; Wilhelmsen, C.A.

    1993-01-01

    The Idaho National Engineering Laboratory is a Department of Energy facility that performs a variety of engineering and research projects. EG G Idaho is the prime contractor for the laboratory and, as such, performs the support functions in addition to technical, research, and development functions. As a part of the EG G Idaho Industrial Hygiene Initiative, ergonomic assessments were conducted at three Idaho National Engineering Laboratory Cafeterias. The purposes of the assessments were to determine whether ergonomic problems existed in the work places and, if so, to make recommendations to improve the work place and task designs. The study showed there were ergonomic problems in all three cafeterias assessed. The primary ergonomic stresses observed included wrist and shoulder stress in the dish washing task, postural stress in the dish washing and food preparation tasks, and back stress in the food handling tasks.

  16. Ergonomic assessments of three Idaho National Engineering Laboratory cafeterias

    Energy Technology Data Exchange (ETDEWEB)

    Ostrom, L.T.; Romero, H.A.; Gilbert, B.G.; Wilhelmsen, C.A.

    1993-05-01

    The Idaho National Engineering Laboratory is a Department of Energy facility that performs a variety of engineering and research projects. EG&G Idaho is the prime contractor for the laboratory and, as such, performs the support functions in addition to technical, research, and development functions. As a part of the EG&G Idaho Industrial Hygiene Initiative, ergonomic assessments were conducted at three Idaho National Engineering Laboratory Cafeterias. The purposes of the assessments were to determine whether ergonomic problems existed in the work places and, if so, to make recommendations to improve the work place and task designs. The study showed there were ergonomic problems in all three cafeterias assessed. The primary ergonomic stresses observed included wrist and shoulder stress in the dish washing task, postural stress in the dish washing and food preparation tasks, and back stress in the food handling tasks.

  17. Effects of lactation upon circulating plasma metabolites in cafeteria-fed rats

    OpenAIRE

    Salvadó, J.; Segués Piqué, Teresa; Alemany, Marià; Arola i Ferrer, Lluís

    1986-01-01

    1. The effects of "cafeteria feeding" on primiparous Wistar rats during lactation have been studied by measuring circulating levels of glucose, amino acids, lactate, urea and ammonia as well as glycogen levels in liver and muscle. 2. No significant changes in glucose levels were observed despite alterations in blood glucose compartmentation. 3. Compared with controls, the dams given the cafeteria diet had higher liver glycogen stores which were more easily mobilized at the peak of lactation. ...

  18. 77 FR 1965 - Central Securities Corporation; Notice of Application

    Science.gov (United States)

    2012-01-12

    ... Bonus Stock to Non-employee Directors without restrictions. Immediately following each annual meeting of... continues as a director after, that annual meeting shall receive an award of 500 Shares of Bonus Stock. In... common stock granted as a bonus, and awards denominated in cash. Applicant: Central...

  19. Determinação de elementos minerais e traços por ativação neutrônica, em refeições servidas no restaurante da Faculdade de Saúde Pública/USP Determination of mineral and trace elements by neutron activation analysis, in meals served at the central cafeteria of Faculty of Public Health/USP

    Directory of Open Access Journals (Sweden)

    Déborah I.T. FÁVARO

    2000-08-01

    estes elementos nos dias estudados.The objective of this research was to check the nutritional adequacy of diets served to University students related to essential elements and also to monitor for some toxic elements. Within this framework, the aim was to determine the levels of these elements in meals served at the Cafeteria of the School of Public Health at USP used by students and workers along one week. The 5 meals served along the week at the Cafeteria were analyzed separately. Three trays per meal were used to collect the food according to a duplicate portion technique. The centesimal composition of the meals was determined according to the methods suggested by AOAC. Neutron Activation Analysis was used and the concentration of the following elements was determined: Ba, Br, Ca, Ce, Cl, Co, Cr, Cs, Fe, K, Mg, Mn, Mo, Na, Rb, Sb, Sc, Se and Zn. The calculated intake obtained in the present work was compared to the daily recommended values set by RDA, WHO and Reference Man. Regarding macronutrients, the protein and lipid levels were high in some cases. The fiber content of the meals was adequate. Concerning the mineral contents of Br, Ca, Fe, Mg, Mn, Rb, Se and Zn, the intake was adequate, but for the elements K, Mo, Na, Cl and Cr, the intake was too high concerning to recommendations. For the elements Ba, Co, Cs and Sb the daily intakes were compared to the values set by Reference Man. There are no recommendations for Ce and Sc elements. A great variability was also observed in the concentrations of these elements during the period of this study.

  20. Obesity induced by cafeteria diet disrupts fertility in the rat by affecting multiple ovarian targets.

    Science.gov (United States)

    Bazzano, M V; Torelli, C; Pustovrh, M C; Paz, D A; Elia, E M

    2015-11-01

    Obesity constitutes a health problem of increasing worldwide prevalence. Among the health detriments caused by obesity, reproduction is disrupted. However, the mechanisms involved in this disruption are not fully understood. Animals fed a cafeteria diet constitute the model for the study of obesity that most closely reflects Western diet habits. The aims of this study were to evaluate whether a cafeteria diet affects ovarian function and to contribute to the understanding of the mechanisms involved. For that purpose, 22-day-old female Wistar rats were fed ad libitum with a standard diet (control group; n = 20) or cafeteria diet (CAF group; n = 20). The cafeteria diet induced obesity and hyperglycaemia, without altering serum triglycerides, cholesterol or C-reactive protein concentrations. This diet also altered ovarian function: the rats showed prolonged dioestrous phases, decreased serum oestradiol concentrations and increased number of antral atretic follicles. Moreover, follicular cysts were detected in the CAF group, concomitantly with a decrease in the number of anti-Müllerian hormone immunoreactive pre-antral follicles and COX-2-positive antral and pre-ovulatory follicles. The authors conclude that a cafeteria diet reduces ovarian reserve, induces the presence of follicular cysts and disturbs the ovulatory process, leading to the delayed pregnancy observed in these animals.

  1. Same spaces, different races: what can cafeteria seating patterns tell us about intergroup relations in middle school?

    Science.gov (United States)

    Echols, Leslie; Solomon, Brett J; Graham, Sandra

    2014-10-01

    Using 2 segregation indices--an exposure index previously used in cafeteria studies and an entropy index used for the first time, to our knowledge, in this study--we examined racial segregation in seating patterns among ethnically diverse middle school students in their school cafeteria over a 2-week period. Given the representation of groups in the cafeteria each day, results indicated the expected amount of contact between Asian and White students, but more limited contact between Asian and Latino students and between White and Latino students. Latino students, who were in the numerical majority in the sample, appeared least likely to contribute to overall segregation in the cafeteria. Implications for using the cafeteria methodology to examine intergroup relations were discussed. PMID:25111541

  2. Chocolate Milk Consequences: A Pilot Study Evaluating the Consequences of Banning Chocolate Milk in School Cafeterias

    OpenAIRE

    Hanks, Andrew S.; Just, David R; Brian Wansink

    2014-01-01

    OBJECTIVES: Currently, 68.3% of the milk available in schools is flavored, with chocolate being the most popular (61.6% of all milk). If chocolate milk is removed from a school cafeteria, what will happen to overall milk selection and consumption? METHODS: In a before-after study in 11 Oregon elementary schools, flavored milk-which will be referred to as chocolate milk-was banned from the cafeteria. Milk sales, school enrollment, and data for daily participation in the National School Lunch P...

  3. The Effect of Price Reduction on Salad Bar Purchases at a Corporate Cafeteria

    Science.gov (United States)

    Pronk, Nicolaas P.; Katz, Abigail S.; Tillema, Juliana O.; Flottemesch, Thomas J.

    2013-01-01

    The objective of this study was to determine the effect of a price reduction on salad bar purchases in a corporate cafeteria. We reduced the price of salad bar purchases by 50% during March 2012 and analyzed sales data by month for February through June 2012. We also conducted an anonymous survey. Salad bar sales by weight more than tripled during the price reduction and returned to baseline afterward. Survey respondents reported that the high price of salad relative to other choices is a barrier to purchases. Policies that make the price of salads equal to other choices in cafeterias may significantly increase healthful food consumption. PMID:23428084

  4. Environmental applications of ion chromatography in Eastern and Central Europe.

    Science.gov (United States)

    Michalski, Rajmund

    2010-08-01

    Environmental analytics is one of the most important applications of ion chromatography. It includes determination of ions in water and wastewater as well as in gaseous and solid ones. Nowadays, ion chromatography has almost completely displaced the classical methods of ion determination in these areas. In spite of the fact that the ion chromatography has been officially present in the scientific world for 36 years, its role and popularity is highly diversified in various countries and regions of the world. In highly industrialized countries, it has been a reference method of water and wastewater analysis for years. In other parts of the world, it is not used and appreciated sufficiently despite its undeniable advantages. The following paper is a short overview of the most highly cited scientific and research institutions that conduct research in terms of environmental applications of ion chromatography in Eastern and Central Europe. Furthermore, the paper presents a list of a number of scientific papers referring to the discussed area, published in the years 1996-2009 in some of the most highly cited international scientific journals, and concerning publications of scientists from Eastern and Central Europe seen against the background of Europe and the world.

  5. Schools′ cafeteria status: Does it affect snack patterns? a qualitative study

    Directory of Open Access Journals (Sweden)

    Fatemeh Esfarjani

    2013-01-01

    Full Text Available Background: The aim of this study was to evaluate patterns of students′ snacks habits regarding to their schools′ cafeteria status in Tehran by focus group discussion (FGD technique. Methods: Participants were 240 students (12-15 years old, selected from12 middle-schools in Tehran. The field study consisted of 24 FGDs sessions; involving 8-10 participants. Collected data were coded, categorized and analyzed using constant comparative method. Results: Over half of the students believed that snack consumption is necessary. Although, majority of students believed that their schools′ cafeterias are not acceptable, they noted them as one of the necessary parts of school. Nearly half of the children were complaining of unvaried and expensive food items. The most purchased items were: Cookies, sandwiches with mayonnaise and ketchup, soft drinks and chocolate milk. Most of the students were interested in having roles in their cafeterias. Conclusions: Schools′ cafeteria are significant sources of supplying adolescents′ snacks, so developing hygienic stores containing healthy and nutritious food items is a key element to affect their snack selection positively. Reaching this goal requires a multi disciplinary approach through participation of students, school staff, parents, and the support of community and media.

  6. A Group Contingency Program to Improve the Behavior of Elementary School Students in a Cafeteria

    Science.gov (United States)

    Fabiano, Gregory A.; Pelham, William E., Jr.; Karmazin, Karen; Kreher, Joanne; Panahon, Carlos J.; Carlson, Carl

    2008-01-01

    Studies of behavior modification interventions for disruptive behavior in schools have generally focused on classroom behavior with less research directed toward child behavior in other school settings (e.g., cafeterias). The present report documents the effect of a group contingency intervention with a random reward component, targeting…

  7. Effect of Food Service Nutrition Improvements on Elementary School Cafeteria Lunch Purchase Patterns

    Science.gov (United States)

    Cluss, Patricia A.; Fee, LuAnn; Culyba, Rebecca J.; Bhat, Kiran B.; Owen, Kay

    2014-01-01

    Background: Schools can play a major role in prevention and intervention for childhood obesity. We describe changes in elementary school cafeteria lunch sales patterns resulting from nutritional improvements in menu offerings that were part of a community-wide focus on health. Methods: Elementary school lunch sales data were collected for 1 week…

  8. The impact of educational and environmental interventions in Dutch worksite cafeterias

    NARCIS (Netherlands)

    I.H.M. Steenhuis; P. van Assema (Patricia); G.J.P. van Breukelen (Gerard); K. Glanz; G.J. Kok (Gerjo); H. de Vries (Hein)

    2004-01-01

    textabstractEnvironmental interventions as labeling of healthy foods and an increased availability of healthy foods may help consumers to meet the guidelines for a healthy diet. This article describes a study into the effectiveness of two environmental programs to be used in worksite cafeterias alon

  9. Applications of Nanotechnology to the Central Nervous System

    Science.gov (United States)

    Blumling, James P., II

    Nanotechnology and nanomaterials, in general, have become prominent areas of academic research. The ability to engineer at the nano scale is critical to the advancement of the physical and medical sciences. In the realm of physical sciences, the applications are clear: smaller circuitry, more powerful computers, higher resolution intruments. However, the potential impact in the fields of biology and medicine are perhaps even grander. The implementation of novel nanodevices is of paramount importance to the advancement of drug delivery, molecular detection, and cellular manipulation. The work presented in this thesis focuses on the development of nanotechnology for applications in neuroscience. The nervous system provides unique challenges and opportunities for nanoscale research. This thesis discusses some background in nanotechnological applications to the central nervous system and details: (1) The development of a novel calcium nanosenser for use in neurons and astrocytes. We implemented the calcium responsive component of Dr. Roger Tsien's Cameleon sensor, a calmodulin-M13 fusion, in the first quantum dot-based calcium sensor. (2) The exploration of cell-penetrating peptides as a delivery mechanism for nanoparticles to cells of the nervous system. We investigated the application of polyarginine sequences to rat primary cortical astrocytes in order to assess their efficacy in a terminally differentiated neural cell line. (3) The development of a cheap, biocompatible alternative to quantum dots for nanosensor and imaging applications. We utilized a positively charged co-matrix to promote the encapsulation of free sulforhodamine B in silica nanoparticles, a departure from conventional reactive dye coupling to silica matrices. While other methods have been invoked to trap dye not directly coupled to silica, they rely on positively charged dyes that typically have a low quantum yield and are not extensively tested biologically, or they implement reactive dyes bound

  10. Engineering Biomaterial Properties for Central Nervous System Applications

    Science.gov (United States)

    Rivet, Christopher John

    Biomaterials offer unique properties that are intrinsic to the chemistry of the material itself or occur as a result of the fabrication process; iron oxide nanoparticles are superparamagnetic, which enables controlled heating in the presence of an alternating magnetic field, and a hydrogel and electrospun fiber hybrid material provides minimally invasive placement of a fibrous, artificial extracellular matrix for tissue regeneration. Utilization of these unique properties towards central nervous system disease and dysfunction requires a thorough definition of the properties in concert with full biological assessment. This enables development of material-specific features to elicit unique cellular responses. Iron oxide nanoparticles are first investigated for material-dependent, cortical neuron cytotoxicity in vitro and subsequently evaluated for alternating magnetic field stimulation induced hyperthermia, emulating the clinical application for enhanced chemotherapy efficacy in glioblastoma treatment. A hydrogel and electrospun fiber hybrid material is first applied to a rat brain to evaluate biomaterial interface astrocyte accumulation as a function of hybrid material composition. The hybrid material is then utilized towards increasing functional engraftment of dopaminergic progenitor neural stem cells in a mouse model of Parkinson's disease. Taken together, these two scenarios display the role of material property characterization in development of biomaterial strategies for central nervous system repair and regeneration.

  11. Cafeteria diet induce changes in blood flow that are more related with heat dissipation than energy accretion.

    Science.gov (United States)

    Sabater, David; Agnelli, Silvia; Arriarán, Sofía; Romero, María Del Mar; Fernández-López, José Antonio; Alemany, Marià; Remesar, Xavier

    2016-01-01

    Background. A "cafeteria" diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy. Methods. Male Wistar rats were exposed for a month to "cafeteria" diet. Rats were cannulated and fluorescent microspheres were used to determine blood flow. Results. Exposure to the cafeteria diet did not change cardiac output, but there was a marked shift in organ irrigation. Skin blood flow decreased to compensate increases in lungs and heart. Blood flow through adipose tissue tended to increase in relation to controls, but was considerably increased in brown adipose tissue (on a weight basis). Discussion. The results suggest that the cafeteria diet-induced changes were related to heat transfer and disposal. PMID:27547590

  12. Grape Seed Procyanidin Extract Improves Insulin Production but Enhances Bax Protein Expression in Cafeteria-Treated Male Rats

    Directory of Open Access Journals (Sweden)

    Lídia Cedó

    2013-01-01

    Full Text Available In a previous study, the administration of a grape seed procyanidin extract (GSPE in female Wistar rats improved insulin resistance, reduced insulin production, and modulated apoptosis biomarkers in the pancreas. Considering that pharmacokinetic and pharmacodynamic parameters in females are different from these parameters in males, the aim of the present study was to evaluate the effects of GSPE on male Wistar cafeteria-induced obese rats. The results have confirmed that the cafeteria model is a robust model mimicking a prediabetic state, as these rats display insulin resistance, increased insulin synthesis and secretion, and increased apoptosis in the pancreas. In addition, GSPE treatment (25 mg/kg of GSPE for 21 days in male rats improves insulin resistance and counteracts the cafeteria-induced effects on insulin synthesis. However, the administration of the extract enhances the cafeteria-induced increase in Bax protein levels, suggesting increased apoptosis. This result contradicts previous results from cafeteria-fed female rats, in which GSPE seemed to counteract the increased apoptosis induced by the cafeteria diet.

  13. The impact of educational and environmental interventions in Dutch worksite cafeterias

    OpenAIRE

    Steenhuis, I H M; van Assema, Patricia; Breukelen, Gerard van; Glanz, K; Kok, Gerjo; de Vries, Hein

    2004-01-01

    textabstractEnvironmental interventions as labeling of healthy foods and an increased availability of healthy foods may help consumers to meet the guidelines for a healthy diet. This article describes a study into the effectiveness of two environmental programs to be used in worksite cafeterias along with an educational program. The aim of the interventions was to reduce fat intake and increase fruit and vegetable intake. In the 'Labeling Program', low fat products were labeled. The 'Food Sup...

  14. Small portion sizes in worksite cafeterias: do they help consumers to reduce their food intake?

    OpenAIRE

    Vermeer, W.M.; Steenhuis, I.H.M.; Leeuwis, F H; Heymans, M.W.; Seidell, J. C.

    2011-01-01

    Background: Environmental interventions directed at portion size might help consumers to reduce their food intake. Objective: To assess whether offering a smaller hot meal, in addition to the existing size, stimulates people to replace their large meal with a smaller meal. Design: Longitudinal randomized controlled trial assessing the impact of introducing small portion sizes and pricing strategies on consumer choices. Setting/participants: In all, 25 worksite cafeterias and a panel consistin...

  15. Chocolate milk consequences: a pilot study evaluating the consequences of banning chocolate milk in school cafeterias.

    Directory of Open Access Journals (Sweden)

    Andrew S Hanks

    Full Text Available OBJECTIVES: Currently, 68.3% of the milk available in schools is flavored, with chocolate being the most popular (61.6% of all milk. If chocolate milk is removed from a school cafeteria, what will happen to overall milk selection and consumption? METHODS: In a before-after study in 11 Oregon elementary schools, flavored milk-which will be referred to as chocolate milk-was banned from the cafeteria. Milk sales, school enrollment, and data for daily participation in the National School Lunch Program (NSLP were compared year to date. RESULTS: Total daily milk sales declined by 9.9% (p<0.01. Although white milk increased by 161.2 cartons per day (p<0.001, 29.4% of this milk was thrown away. Eliminating chocolate milk was also associated with 6.8% fewer students eating school lunches, and although other factors were also involved, this is consistent with the notion of psychological reactance. CONCLUSIONS: Removing chocolate milk from school cafeterias may reduce calorie and sugar consumption, but it may also lead students to take less milk overall, drink less (waste more of the white milk they do take, and no longer purchase school lunch. Food service managers need to carefully weigh the costs and benefits of eliminating chocolate milk and should consider alternative options that make white milk more convenient, attractive, and normal to choose.

  16. You Don't Have To Dread Cafeteria Duty: A Guide to Surviving Lunchroom, Recess, Bus, and "Other Duties as Assigned."

    Science.gov (United States)

    Novak, Dori E.; Strohmer, Joanne C.

    This book offers educators ideas, plans, games, and reproducibles for making the school cafeteria into an inviting place where students can learn and have fun. Chapter 1, "The Dreaded School Cafeteria Scene," discusses observing the big picture and getting others involved. Chapter 2, "What Could Be," helps create a vision of what could be. Chapter…

  17. Smoking ban in all restaurants and cafeterias on the CERN site

    CERN Multimedia

    CSR

    2006-01-01

    In 2005 the SCC decided that there would be a total smoking ban in all restaurants and satellite cafeterias on the CERN site, except for the designated area in Restaurant No.1. Unfortunately, it seems that this ban is often over-looked, resulting in an unhealthy and unpleasant environment for the users and staff of these facilities. You are asked to respect this ban and are reminded that smoking is only permitted in the room in Restaurant 1 specially installed for this purpose. The CSR Restaurant Monitoring Committee

  18. 77 FR 41975 - Southern Star Central Gas Pipeline, Inc.; Notice of Application

    Science.gov (United States)

    2012-07-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Southern Star Central Gas Pipeline, Inc.; Notice of Application Take notice that on June 27, 2012, Southern Star Central Gas Pipeline, Inc. (Southern Star), 4700 Highway 56, Owensboro, Kentucky 42301, filed...

  19. 75 FR 74697 - Central Oregon Irrigation District; Notice of Competing Preliminary Permit Application Accepted...

    Science.gov (United States)

    2010-12-01

    ... Energy Regulatory Commission Central Oregon Irrigation District; Notice of Competing Preliminary Permit..., 2010, Central Oregon Irrigation District filed an application for a preliminary permit, pursuant to... diversion control; (4) a 400-foot-long lined canal and flume channel; (5) a 45-foot-long,...

  20. Cafeteria diet inhibits insulin clearance by reduced insulin-degrading enzyme expression and mRNA splicing.

    Science.gov (United States)

    Brandimarti, P; Costa-Júnior, J M; Ferreira, S M; Protzek, A O; Santos, G J; Carneiro, E M; Boschero, A C; Rezende, L F

    2013-11-01

    Insulin clearance plays a major role in glucose homeostasis and insulin sensitivity in physiological and/or pathological conditions, such as obesity-induced type 2 diabetes as well as diet-induced obesity. The aim of the present work was to evaluate cafeteria diet-induced obesity-induced changes in insulin clearance and to explain the mechanisms underlying these possible changes. Female Swiss mice were fed either a standard chow diet (CTL) or a cafeteria diet (CAF) for 8 weeks, after which we performed glucose tolerance tests, insulin tolerance tests, insulin dynamics, and insulin clearance tests. We then isolated pancreatic islets for ex vivo glucose-stimulated insulin secretion as well as liver, gastrocnemius, visceral adipose tissue, and hypothalamus for subsequent protein analysis by western blot and determination of mRNA levels by real-time RT-PCR. The cafeteria diet induced insulin resistance, glucose intolerance, and increased insulin secretion and total insulin content. More importantly, mice that were fed a cafeteria diet demonstrated reduced insulin clearance and decay rate as well as reduced insulin-degrading enzyme (IDE) protein and mRNA levels in liver and skeletal muscle compared with the control animals. Furthermore, the cafeteria diet reduced IDE expression and alternative splicing in the liver and skeletal muscle of mice. In conclusion, a cafeteria diet impairs glucose homeostasis by reducing insulin sensitivity, but it also reduces insulin clearance by reducing IDE expression and alternative splicing in mouse liver; however, whether this mechanism contributes to the glucose intolerance or helps to ameliorate it remains unclear.

  1. Altered feeding patterns in rats exposed to a palatable cafeteria diet: increased snacking and its implications for development of obesity.

    Directory of Open Access Journals (Sweden)

    Sarah I Martire

    Full Text Available BACKGROUND: Rats prefer energy-rich foods over chow and eat them to excess. The pattern of eating elicited by this diet is unknown. We used the behavioral satiety sequence to classify an eating bout as a meal or snack and compared the eating patterns of rats fed an energy rich cafeteria diet or chow. METHODS: Eight week old male Sprague Dawley rats were exposed to lab chow or an energy-rich cafeteria diet (plus chow for 16 weeks. After 5, 10 and 15 weeks, home-cage overnight feeding behavior was recorded. Eating followed by grooming then resting or sleeping was classified as a meal; whereas eating not followed by the full sequence was classified as a snack. Numbers of meals and snacks, their duration, and waiting times between feeding bouts were compared between the two conditions. RESULTS: Cafeteria-fed rats ate more protein, fat and carbohydrate, consistently ingesting double the energy of chow-fed rats, and were significantly heavier by week 4. Cafeteria-fed rats tended to take multiple snacks between meals and ate fewer meals than chow-fed rats. They also ate more snacks at 5 weeks, were less effective at compensating for snacking by reducing meals, and the number of snacks in the majority of the cafeteria-fed rats was positively related to terminal body weights. CONCLUSIONS: Exposure to a palatable diet had long-term effects on feeding patterns. Rats became overweight because they initially ate more frequently and ultimately ate more of foods with higher energy density. The early increased snacking in young cafeteria-fed rats may represent the establishment of eating habits that promote weight gain.

  2. [Peripheral vertigo versus central vertigo. Application of the HINTS protocol].

    Science.gov (United States)

    Batuecas-Caletrío, Ángel; Yáñez-González, Raquel; Sánchez-Blanco, Carmen; González-Sánchez, Enrique; Benito, José; Gómez, José Carlos; Santa Cruz-Ruiz, Santiago

    2014-10-16

    Introduccion. Uno de los dilemas mas importantes concernientes al vertigo en urgencias es su diagnostico diferencial. Existen signos de alarma de gran sensibilidad en la exploracion que pueden ponernos en la pista de encontrarnos ante un vertigo central. Objetivo. Determinar la eficacia de la aplicacion del protocolo HINTS en el diagnostico del accidente cerebrovascular que simula un vertigo periferico. Pacientes y metodos. Estudio observacional descriptivo sobre pacientes ingresados con diagnostico de sindrome vestibular agudo en urgencias. Todos los pacientes fueron objeto de un seguimiento diario hasta la mejoria de sus sintomas con informacion del nistagmo, la maniobra de impulso oculocefalico y el test de skew. Se comparan los resultados del estudio de resonancia magnetica con la alteracion en alguno de esos tres signos a lo largo del ingreso del enfermo. Resultados. Se reunio a 91 pacientes, con una edad media de 55,8 años. Se objetivo un accidente cerebrovascular en ocho de ellos. De estos (edad media: 71 años), en siete existia una alteracion en alguno de los signos HINTS y en uno el estudio fue normal (sensibilidad: 0,88; especificidad: 0,96). Todos ellos tenian algun factor de riesgo vascular. Conclusiones. Una exploracion adecuada y dirigida ante un paciente que acude a urgencias con un sindrome vestibular agudo resulta de vital importancia para establecer el diagnostico diferencial entre la patologia periferica y la central, ya que algunos accidentes cerebrovasculares se pueden presentar bajo la apariencia de un vertigo agudo. Aplicar un protocolo como HINTS permite sospechar la patologia central con una gran sensibilidad y especificidad.

  3. Clinical application of MRI to fetal central nervous system

    International Nuclear Information System (INIS)

    Objective: To explore the value of MRI on fetal central nervous system. Methods: Twenty-four women with complicated pregnancies, aged from 22 to 32 years (average 27 years) and with gestation from 23-39 weeks (average 30 weeks) were studied with a 1.5T superconductive MR unit within 24 hours after ultrasound studies. T2-weighted MR imaging was performed using HASTE and T1-weighted MR imaging was using FLASH. Comparison of the diagnosis of MRI and ultrasound were done with autopsy or postnatal follow-up MRI. Results: Of the 24 cases, 24 fetus were found. The fetal brain, gyrus, sulcus, corpus callosum, thalamus, cerebellum, brain stem, and spinal cord were shown more clearly on MR T2-weighted images. T1-weighted images were not as good as T2-weighted images. Twenty-seven lesions were visualized by ultrasound and thirty-one by MRI in these twenty-four fetuses. By MRI study, two cases were conformed their ultrasound diagnosis, ten cases were completed their ultrasound diagnosis, and twelve cases were made the same diagnosis as ultrasound. Conclusion: MR has advantages in displaying fetal central nervous system anatomy over ultrasound, the quality of MR images is not affected by maternal somatotype, volume of amniotic fluid, fetal skull and the pelvic skeleton of pregnant women. Based on ultrasound, MR imaging is a valuable complement to sonography in difficult cases, it can conforming, completing, even more correcting the diagnosis made by ultrasound. (authors)

  4. Effect of Argyreia speciosa root extract on cafeteria diet-induced obesity in rats

    Directory of Open Access Journals (Sweden)

    Shiv Kumar

    2011-01-01

    Full Text Available Objectives : To evaluate the antiobesity effects of the ethanolic extract of Argyreia speciosa roots in rats fed with a cafeteria diet (CD. Materials and Methods : Obesity was induced in albino rats by feeding them a CD daily for 42 days, in addition to a normal diet. Body weight and food intake was measured initially and then every week thereafter. On day 42, the serum biochemical parameters were estimated and the animals were sacrificed with an overdose of ether. The, liver and parametrial adipose tissues were removed and weighed immediately. The liver triglyceride content was estimated. The influence of the extract on the pancreatic lipase activity was also determined by measuring the rate of release of oleic acid from triolein. Results : The body weight at two-to-six weeks and the final parametrial adipose tissue weights were significantly lowered (P < 0.01 and P < 0.05, respectively in rats fed with the CD with Argyreia speciosa extract 500 mg/kg/day as compared to the CD alone. The extract also significantly reduced (P < 0.01 the serum contents of leptin, total cholesterol, low density lipoprotein (LDL, and triglycerides, which were elevated in rats fed with CD alone. In addition, the extract inhibited the induction of fatty liver with the accumulation of hepatic triglycerides. The extract also showed inhibition of pancreatic lipase activity by using triolein as a substrate. Conclusions : The ethanolic extract of Argyreia speciosa roots produces inhibitory effects on cafeteria diet-induced obesity in rats.

  5. The Relationship between Nutrition Knowledge and School Cafeteria Purchases of Seventh Grade Students in a Rural Indiana School District

    Science.gov (United States)

    Pucciarelli, Deanna; McNeany, Terry; Friesen, Carol

    2013-01-01

    Purpose/Objective: School cafeterias have the potential to positively contribute to the prevention and treatment of childhood obesity. The purpose of this project was to assess adolescents' nutrition knowledge and dietary choices, and to measure the relationship between students' nutrition knowledge and the type of food items purchased…

  6. Project Refresh: Testing the Efficacy of a School-Based Classroom and Cafeteria Intervention in Elementary School Children

    Science.gov (United States)

    Song, Hee-Jung; Grutzmacher, Stephanie; Munger, Ash L.

    2016-01-01

    Background: The purpose of this study was to assess the effect of a school-based nutrition program using a cafeteria environment intervention and classroom nutrition education on self-reported fruit and vegetable (FV) consumption, self-efficacy to select FV, and preference for healthy foods. Methods: Using quasi-experimental pre-post design with 3…

  7. A Pricing Strategy To Promote Sales of Lower Fat Foods in High School Cafeterias: Acceptability and Sensitivity Analysis.

    Science.gov (United States)

    Hannan, Peter; French, Simone A.; Story, Mary; Fulkerson, Jayne A.

    2002-01-01

    Examined the purchase patterns of seven targeted foods under conditions in which prices of three high-fat foods were raised and prices of four low-fat foods were lowered in a high school cafeteria over 1 school year. Data collected on food sales and revenues supported the feasibility of a pricing strategy that offered low-fat foods at lower prices…

  8. West Texas nursing education portal project: developing a regional centralized application system.

    Science.gov (United States)

    Allen, Patricia; Billings, Lynda; Cannon, Sharon; Majors, Jennifer; Sportsman, Susan; Ballesteros, Pauline A; Bezinque, Kim; Bolton, Cathy; Cottenoir, Marla; Edwards, Carmen; Louder, Justin; O'Neal, Cynthia; Morgan, Jackolyn; Reyes, Helen; Ross, Linda

    2011-01-01

    Because of the nursing shortage and a demand for maximum enrollment, a group of five baccalaureate and seven associate degree nursing programs in West Texas first met in 2007 to form the West Texas Nursing Education Consortium (WTNEC). To emphasize the importance of scale and distance, the West Texas region is larger than all of the northeastern states combined. The founding group agreed that the first mission of WTNEC should be to pool resources in order to increase admission and graduation rates for WTNEC schools. Two years later, this mission is being accomplished by the implementation of a plan designed to increase participating schools' admissions, retention, and graduation rates. A grant proposal was written and funded to develop a central regionalization of the application process for entry into WTNEC generic programs (associates degree in nursing and bachelor of science in nursing), with the goal of decreasing and possibly eliminating student vacancy rates in member schools and perhaps reducing the resources needed by each school for the admission process. The implemented centralized application system allowed prospective students to apply online to the centralized admission portal. Students maintained the freedom to choose the nursing program(s) they wanted to attend, but they were also made aware of possible openings in other participating schools. The admission portal also saved potential students time and money by submitting one centralized application, resulting in consolidation of the nursing school application process. Eleven of the 12 consortium schools participated in the centralized application system. PMID:21596353

  9. Cafeteria Computers.

    Science.gov (United States)

    Dervarics, Charles

    1992-01-01

    By relying on new computer hardware and software, school food service departments can keep better records of daily food consumption, free and reduced-price meals, inventory, production, and other essentials. The most commonly used systems fall into two basic categories: point-of-sale computers and behind-the-counter systems. State funding efforts…

  10. CentiServer: A Comprehensive Resource, Web-Based Application and R Package for Centrality Analysis.

    Directory of Open Access Journals (Sweden)

    Mahdi Jalili

    Full Text Available Various disciplines are trying to solve one of the most noteworthy queries and broadly used concepts in biology, essentiality. Centrality is a primary index and a promising method for identifying essential nodes, particularly in biological networks. The newly created CentiServer is a comprehensive online resource that provides over 110 definitions of different centrality indices, their computational methods, and algorithms in the form of an encyclopedia. In addition, CentiServer allows users to calculate 55 centralities with the help of an interactive web-based application tool and provides a numerical result as a comma separated value (csv file format or a mapped graphical format as a graph modeling language (GML file. The standalone version of this application has been developed in the form of an R package. The web-based application (CentiServer and R package (centiserve are freely available at http://www.centiserver.org/.

  11. A cafeteria diet modifies the response to chronic variable stress in rats.

    Science.gov (United States)

    Zeeni, N; Daher, C; Fromentin, G; Tome, D; Darcel, N; Chaumontet, C

    2013-03-01

    Stress is known to lead to metabolic and behavioral changes. To study the possible relationships between stress and dietary intake, male Sprague-Dawley rats were fed one of three diets for 6 weeks: high carbohydrate (HC), high fat (HF), or "Cafeteria" (CAF) (Standard HC plus a choice of highly palatable cafeteria foods: chocolate, biscuits, and peanut butter). After the first 3 weeks, half of the animals from each group (experimental groups) were stressed daily using a chronic variable stress (CVS) paradigm, while the other half of the animals (control groups) were kept undisturbed. Rats were sacrificed at the end of the 6-week period. The effects of stress and dietary intake on animal adiposity, serum lipids, and corticosterone were analyzed. Results showed that both chronic stress and CAF diet resulted in elevated total cholesterol, increased low-density lipoprotein (LDL), and lower high-density lipoprotein (HDL). In addition, increases in body weight, food intake, and intra-abdominal fat were observed in the CAF group compared with the other dietary groups. In addition, there was a significant interaction between stress and diet on serum corticosterone levels, which manifest as an increase in corticosterone levels in stressed rats relative to non-stressed controls in the HC and HF groups but not in the CAF group. These results show that a highly palatable diet, offering a choice of food items, is associated with a reduction in the response to CVS and could validate a stressor-induced preference for comfort food that in turn could increase body weight.

  12. Process evaluation of two environmental nutrition programmes and an educational nutrition programme conducted at supermarkets and worksite cafeterias in the Netherlands

    NARCIS (Netherlands)

    I.H.M. Steenhuis; P. van Assema (Patricia); A. Reubsaet; G.J. Kok (Gerjo)

    2004-01-01

    textabstractThis article describes the process evaluation of two environmental programs and a educational nutrition program, implemented at supermarkets and worksite cafeterias. Studies conducted earlier, indicated that the programs had no effect on consumers’ eating behavior. Consequently, the more

  13. Recycled Water Reuse Permit Renewal Application for the Central Facilities Area Sewage Treatment Plant

    Energy Technology Data Exchange (ETDEWEB)

    Mike Lewis

    2014-09-01

    This renewal application for a Recycled Water Reuse Permit is being submitted in accordance with the Idaho Administrative Procedures Act 58.01.17 “Recycled Water Rules” and the Municipal Wastewater Reuse Permit LA-000141-03 for continuing the operation of the Central Facilities Area Sewage Treatment Plant located at the Idaho National Laboratory. The permit expires March 16, 2015. The permit requires a renewal application to be submitted six months prior to the expiration date of the existing permit. For the Central Facilities Area Sewage Treatment Plant, the renewal application must be submitted by September 16, 2014. The information in this application is consistent with the Idaho Department of Environmental Quality’s Guidance for Reclamation and Reuse of Municipal and Industrial Wastewater and discussions with Idaho Department of Environmental Quality personnel.

  14. Wastewater Land Application Permit LA-000141 Renewal Information for the Central Facilities Area Sewage Treatment Plant

    Energy Technology Data Exchange (ETDEWEB)

    Laboratory, Idaho National

    1999-02-01

    On July 25, 1994, the State ofldaho Division of Environmental Quality (DEQ) issued a Wastewater Land Application Permit (WLAP) for the Idaho National Engineering Laboratory's (INEL, now the Idaho National Engineering and Environmental Laboratory [INEEL]) Central Facilities Area (CFA) Sewage Treatment Plant (STP). The permit expires August 7, 1999. In addition to the renewal application, this report was prepared to provide the following information as requested by DEQ.

  15. Effects of the cafeteria diet on the salivary glands of trained and sedentary Wistar rats=Efeitos da dieta de cafeteria sobre as glândulas salivares de ratos Wistar sedentários e treinados

    Directory of Open Access Journals (Sweden)

    Sonia Lucy Molinari

    2012-01-01

    Full Text Available The objective of this work was to study the effect of the aerobic physical training and the cafeteria diet introduced after weaning of Wistar rats and on the morphology of the main salivary glands (parotid, submandibular, sublingual. Male rats after weaning were subjected to the cafeteria diet or the standard rodent chow, and either performed aerobic physical training in a treadmill for 100 days, or did not performed any physical activity. Analyses were done considering the response in body weight, adipose tissues and salivary glands, and the data were submitted to statistical treatment (p O objetivo deste trabalho foi avaliar as características morfológicas das glândulas salivares (parótida, submandibular, sublingual apresentadas por ratos submetidos a treinamento físico aeróbio e dieta de cafeteria após o período de lactação. Ratos machos após a lactação consumiram dieta de cafeteria ou ração-padrão para roedores e realizaram treinamento físico aeróbio em esteira rolante por um período de 100 dias, ou não realizaram nenhuma atividade física. Foram feitas análises sobre a resposta do peso corporal, dos tecidos adiposos e das glândulas salivares e os dados submetidos a tratamento estatístico (p < 0,05. A análise morfológica e morfométrica das glândulas salivares foi realizada a partir de cortes histológicos corados com Hematoxilina e Eosina. Apesar do comportamento normofágico, os roedores alimentados com dieta de cafeteria apresentaram maior quantidade de gordura corporal, com repercussão sobre o peso da glândula parótida. A análise morfométrica das glândulas submandibulares indicou redução na proporção dos ácinos serosos como efeito da dieta de cafeteria e do treinamento físico. No entanto, excesso de gordura corporal, dieta de cafeteria e/ou treinamento físico não influenciou a organização histológica das glândulas salivares. Concluiu-se que as glândulas parótidas e submandibulares são mais

  16. Hypolipidemic and weight reducing activity of the ethanolic extract of Tamarindus indica fruit pulp in cafeteria diet- and sulpiride-induced obese rats

    Directory of Open Access Journals (Sweden)

    Vaneeta Jindal

    2011-01-01

    Full Text Available Objectives: To investigate the effect of ethanolic extract of fruit pulp of Tamarindus indica Linn. (Family: Caesalpiniaceae on obesity in rats using cafeteria diet-induced obesity and antipsychotic drug (sulpiride-induced obesity. Materials and Methods: Cafeteria diet was administered for 40 successive days to male Wistar rats and sulpiride (20 mg/kg, i.p. was administered for 28 successive days to female Wistar rats. In separate groups of animals, the ethanolic extract (50 and 100 mg/kg p.o. of Tamarindus indica fruit was administered along with cafeteria diet for 40 successive days to Wistar male rats and along with sulpiride for 28 successive days to Wistar female rats. Results: Cafeteria diet alone significantly increased body weight, serum total cholesterol, triglycerides, and glucose levels and decreased HDL cholesterol in male rats as compared to control. Sulpiride per se significantly increased the levels of glucose, triglycerides, cholesterol and there was no significant effect on HDL-cholesterol in female rats as compared to control. Ethanolic extract showed a significant decrease in body weight, serum cholesterol, and triglycerides and a significant increase in HDL-cholesterol in cafeteria diet- and sulpiride-induced obese rats as compared to their respective control groups. Conclusions: Thus, the ethanolic extract of Tamarindus indica fruit pulp showed a significant weight-reducing and hypolipidemic activity in cafeteria diet- and sulpiride-induced obese rats.

  17. Planning and development of the Better Bites program: a pricing manipulation strategy to improve healthy eating in a hospital cafeteria.

    Science.gov (United States)

    Liebert, Mina L; Patsch, Amy J; Smith, Jennifer Howard; Behrens, Timothy K; Charles, Tami; Bailey, Taryn R

    2013-07-01

    The Better Bites program, a hospital cafeteria nutrition intervention strategy, was developed by combining evidence-based practices with hospital-specific formative research, including key informant interviews, the Nutrition Environment Measures Study in Restaurants, hospital employee surveys, and nutrition services staff surveys. The primary program components are pricing manipulation and marketing to promote delicious, affordable, and healthy foods to hospital employees and other cafeteria patrons. The pricing manipulation component includes decreasing the price of the healthy items and increasing the price of the unhealthy items using a 35% price differential. Point-of-purchase marketing highlights taste, cost, and health benefits of the healthy items. The program aims to increase purchases of healthy foods and decrease purchases of unhealthy foods, while maintaining revenue neutrality. This article addresses the formative research, planning, and development that informed the Better Bites program.

  18. Cafeteria diet induce changes in blood flow that are more related with heat dissipation than energy accretion

    Science.gov (United States)

    Sabater, David; Agnelli, Silvia; Arriarán, Sofía; Romero, María del Mar; Fernández-López, José Antonio; Alemany, Marià

    2016-01-01

    Background. A “cafeteria” diet is a self-selected high-fat diet, providing an excess of energy, which can induce obesity. Excess of lipids in the diet hampers glucose utilization eliciting insulin resistance, which, further limits amino acid oxidation for energy. Methods. Male Wistar rats were exposed for a month to “cafeteria” diet. Rats were cannulated and fluorescent microspheres were used to determine blood flow. Results. Exposure to the cafeteria diet did not change cardiac output, but there was a marked shift in organ irrigation. Skin blood flow decreased to compensate increases in lungs and heart. Blood flow through adipose tissue tended to increase in relation to controls, but was considerably increased in brown adipose tissue (on a weight basis). Discussion. The results suggest that the cafeteria diet-induced changes were related to heat transfer and disposal. PMID:27547590

  19. Wastewater Land Application Permit LA-000141 Renewal Information for the Central Facilities Area Sewage Treatment Plant

    Energy Technology Data Exchange (ETDEWEB)

    None

    1999-02-01

    On July 25, 1994, the State of ldaho Division of Environmental Quality issued a Wastewater Land Application Permit, #LA-000141-01, for the Central Facilities Area Sewage Treatment Plant. The permit expires August 7, 1999. This report is being submitted with the renewal application and specifically addresses; Wastewater flow; Wastewater characteristics; Impacts to vegetation in irrigation area; Impacts to soil in irrigation area; Evaluation of groundwater monitoring wells for Wastewater Land Application Permit purposes; Summary of trends observed during the 5-year reporting period; and Projection of changes and new processes.

  20. Effect of point-of-purchase calorie labeling on restaurant and cafeteria food choices: A review of the literature

    Directory of Open Access Journals (Sweden)

    French Simone A

    2008-10-01

    Full Text Available Abstract Background Eating away from home has increased in prevalence among US adults and now comprises about 50% of food expenditures. Calorie labeling on chain restaurant menus is one specific policy that has been proposed to help consumers make better food choices at restaurants. The present review evaluates the available empirical literature on the effects of calorie information on food choices in restaurant and cafeteria settings. Methods Computer-assisted searches were conducted using the PUBMED database and the Google Scholar world wide web search engine to identify studies published in peer-review journals that evaluated calorie labeling of cafeteria or restaurant menu items. Studies that evaluated labeling only some menu items (e.g. low calorie foods only were excluded from the review since the influence of selective labeling may be different from that which may be expected from comprehensive labeling. Results Six studies were identified that met the selection criteria for this review. Results from five of these studies provide some evidence consistent with the hypothesis that calorie information may influence food choices in a cafeteria or restaurant setting. However, results from most of these studies suggest the effect may be weak or inconsistent. One study found no evidence of an effect of calorie labeling on food choices. Each of the studies had at least one major methodological shortcoming, pointing toward the need for better designed studies to more rigorously evaluate the influence of point-of-purchase calorie labeling on food choices. Conclusion More research is needed that meets minimum standards of methodological quality. Studies need to include behavioral outcomes such as food purchase and eating behaviors. Also, studies need to be implemented in realistic settings such as restaurants and cafeterias.

  1. Effect of point-of-purchase calorie labeling on restaurant and cafeteria food choices: A review of the literature

    OpenAIRE

    French Simone A; Harnack Lisa J

    2008-01-01

    Abstract Background Eating away from home has increased in prevalence among US adults and now comprises about 50% of food expenditures. Calorie labeling on chain restaurant menus is one specific policy that has been proposed to help consumers make better food choices at restaurants. The present review evaluates the available empirical literature on the effects of calorie information on food choices in restaurant and cafeteria settings. Methods Computer-assisted searches were conducted using t...

  2. Hypercaloric cafeteria-like diet induced UCP3 gene expression in skeletal muscle is impaired by hypothyroidism

    Directory of Open Access Journals (Sweden)

    Christoffolete M.A.

    2004-01-01

    Full Text Available The uncoupling protein UCP3 belongs to a family of mitochondrial carriers located in the inner mitochondrial membrane of certain cell types. It is expressed almost exclusively at high levels in skeletal muscle and its physiological role has not been fully determined in this tissue. In the present study we have addressed the possible interaction between a hypercaloric diet and thyroid hormone (T3, which are strong stimulators of UCP3 gene expression in skeletal muscle. Male Wistar rats weighing 180 ± 20 g were rendered hypothyroid by thyroidectomy and the addition of methimazole (0.05%; w/v to drinking water after surgery. The rats were fed a hypercaloric cafeteria diet (68% carbohydrates, 13% protein and 18% lipids for 10 days and sacrificed by decapitation. Subsequently, the gastrocnemius muscle was dissected, total RNA was isolated with Trizol? and UCP3 gene expression was determined by Northern blotting using a specific probe. Statistical analysis was performed by one-way analysis of variance (ANOVA followed by the Student-Newman-Keuls post-test. Skeletal muscle UCP3 gene expression was decreased by 60% in hypothyroid rats and UCP3 mRNA expression was increased 70% in euthyroid cafeteria-fed rats compared to euthyroid chow-fed animals, confirming previous studies. Interestingly, the cafeteria diet was unable to stimulate UCP3 gene expression in hypothyroid animals (40% lower as compared to euthyroid cafeteria-fed animals. The results show that a hypercaloric diet is a strong stimulator of UCP3 gene expression in skeletal muscle and requires T3 for an adequate action.

  3. Effect of point-of-purchase calorie labeling on restaurant and cafeteria food choices: A review of the literature

    Science.gov (United States)

    Harnack, Lisa J; French, Simone A

    2008-01-01

    Background Eating away from home has increased in prevalence among US adults and now comprises about 50% of food expenditures. Calorie labeling on chain restaurant menus is one specific policy that has been proposed to help consumers make better food choices at restaurants. The present review evaluates the available empirical literature on the effects of calorie information on food choices in restaurant and cafeteria settings. Methods Computer-assisted searches were conducted using the PUBMED database and the Google Scholar world wide web search engine to identify studies published in peer-review journals that evaluated calorie labeling of cafeteria or restaurant menu items. Studies that evaluated labeling only some menu items (e.g. low calorie foods only) were excluded from the review since the influence of selective labeling may be different from that which may be expected from comprehensive labeling. Results Six studies were identified that met the selection criteria for this review. Results from five of these studies provide some evidence consistent with the hypothesis that calorie information may influence food choices in a cafeteria or restaurant setting. However, results from most of these studies suggest the effect may be weak or inconsistent. One study found no evidence of an effect of calorie labeling on food choices. Each of the studies had at least one major methodological shortcoming, pointing toward the need for better designed studies to more rigorously evaluate the influence of point-of-purchase calorie labeling on food choices. Conclusion More research is needed that meets minimum standards of methodological quality. Studies need to include behavioral outcomes such as food purchase and eating behaviors. Also, studies need to be implemented in realistic settings such as restaurants and cafeterias. PMID:18950529

  4. INTERGEO - Central/East European Collaboration Network on direct application of geothermal energy

    Energy Technology Data Exchange (ETDEWEB)

    Popovski, K. [Central/East European Collaboration Network on Direct Application of Geothermal Energy, Bitola (Yugoslavia); Arpasi, M. [International Geothermal Association - European Branch, Budapest (Hungary)

    1997-12-01

    A proposal for organisation of a Network to be known as INTERGEO is presented, which should extend and reinforce the cooperation for the development of the direct application of geothermal energy between the developed EC countries and the ones of the so called Central/East European region. Unter the term `developed countries` for this particular energy source utilisation mainly Italy, France and Germany should be understood. The Central/East European region consists the following countries: Albania, Bosnia and Herzegovina, Bulgaria, Belarus, Croatia, Czech Republic, Estonia, Hungary, Latvia, Lituania, Macedonia, Moldova, Poland, Roumania, Slovenia, Slovakia, Turkey, Ukraine and Yugoslavia. The idea itself, the need and possibilities for organisation, possible plan of action and expected benefits for the EC and Central/East European countries are elaborated in order to come to the conclusions for the proposal justifiableness and feasibility for realisation. (orig.)

  5. Central Sensitization in Functional Chronic Pain Syndromes: Overview and Clinical Application.

    Science.gov (United States)

    Bettini, Liz; Moore, Ki

    2016-10-01

    The purpose of this review and clinical application article is to offer nurses up-to-date knowledge on peripheral and central sensitization in chronic functional pain syndromes, and to discuss therapies that have shown efficacy in treating various aspects of these disorders. Central sensitization is a result of changes in the peripheral and central nervous system due to noxious stimuli, such as illness or trauma. Once these changes occur, treatment for the associated syndromes requires a multimodal approach that includes behavioral pain psychology, physical therapy, and pharmacological agents that specifically target neuroinflammation, pain modulation, and amplification of pain pathways. More research needs to be conducted on the basis and patient perception of functional pain syndromes to reduce the morbidity and significant disability associated with these illnesses. Nurses have the opportunity to be at the forefront of this research because of their holistic and multidimensional approach to patient care, assessment, and symptom management. PMID:27553129

  6. Marked increase in rat red blood cell membrane protein glycosylation by one-month treatment with a cafeteria diet.

    Science.gov (United States)

    Oliva, Laia; Baron, Cristian; Fernández-López, José-Antonio; Remesar, Xavier; Alemany, Marià

    2015-01-01

    Background and Objectives. Glucose, an aldose, spontaneously reacts with protein amino acids yielding glycosylated proteins. The compounds may reorganize to produce advanced glycosylation products, which regulatory importance is increasingly being recognized. Protein glycosylation is produced without the direct intervention of enzymes and results in the loss of function. Glycosylated plasma albumin, and glycosylated haemoglobin are currently used as index of mean plasma glucose levels, since higher glucose availability results in higher glycosylation rates. In this study we intended to detect the early changes in blood protein glycosylation elicited by an obesogenic diet. Experimental Design. Since albumin is in constant direct contact with plasma glucose, as are the red blood cell (RBC) membranes, we analyzed their degree or glycosylation in female and male rats, either fed a standard diet or subjected to a hyper-energetic self-selected cafeteria diet for 30 days. This model produces a small increase in basal glycaemia and a significant increase in body fat, leaving the animals in the initial stages of development of metabolic syndrome. We also measured the degree of glycosylation of hemoglobin, and the concentration of glucose in contact with this protein, that within the RBC. Glycosylation was measured by colorimetric estimation of the hydroxymethylfurfural liberated from glycosyl residues by incubation with oxalate. Results. Plasma glucose was higher in cafeteria diet and in male rats, both independent effects. However, there were no significant differences induced by sex or diet in either hemoglobin or plasma proteins. Purified RBC membranes showed a marked effect of diet: higher glycosylation in cafeteria rats, which was more marked in females (not in controls). In any case, the number of glycosyl residues per molecule were higher in hemoglobin than in plasma proteins (after correction for molecular weight). The detected levels of glucose in RBC were lower

  7. Effect of cafeteria diet history on cue-, pellet-priming-, and stress-induced reinstatement of food seeking in female rats.

    Directory of Open Access Journals (Sweden)

    Yu-Wei Chen

    Full Text Available BACKGROUND: Relapse to unhealthy eating habits is a major problem in human dietary treatment. The individuals most commonly seeking dietary treatment are overweight or obese women, yet the commonly used rat reinstatement model to study relapse to palatable food seeking during dieting primarily uses normal-weight male rats. To increase the clinical relevance of the relapse to palatable food seeking model, here we pre-expose female rats to a calorically-dense cafeteria diet in the home-cage to make them overweight prior to examining the effect of this diet history on cue-, pellet-priming- and footshock-induced reinstatement of food seeking. METHODS: Post-natal day 32 female Long-Evans rats had seven weeks of home-cage access to either chow only or daily or intermittent cafeteria diet alongside chow. Next, they were trained to self-administer normally preferred 45 mg food pellets accompanied by a tone-light cue. After extinction, all rats were tested for reinstatement induced by discrete cue, pellet-priming, and intermittent footshock under extinction conditions. RESULTS: Access to daily cafeteria diet and to a lesser degree access to intermittent cafeteria diet decreased food pellet self-administration compared to chow-only. Prior history of these cafeteria diets also reduced extinction responding, cue- and pellet-priming-induced reinstatement. In contrast, modest stress-induced reinstatement was only observed in rats with a history of daily cafeteria diet. CONCLUSION: A history of cafeteria diet does not increase the propensity for cue- and pellet-priming-induced relapse in the rat reinstatement model but does appear to make rats more susceptible to footshock stress-induced reinstatement.

  8. On the Risk Management with Application of Econophysics Analysis in Central Banks and Financial Institutions

    OpenAIRE

    Ledenyov, Dimitri O.; Ledenyov, Viktor O.

    2012-01-01

    The purpose of this research article is to discover how the econophysics analysis can complement the econometrics models in application to the risk management in the central banks and financial institutions, operating within the nonlinear dynamical financial system. We consider the modern risk management models and show the appropriate techniques to calculate the various existing risks in the finances. We make a few comments on the possible limitations in the models of statistical modeling of...

  9. Leptin signal transduction underlies the differential metabolic response of LEW and WKY rats to cafeteria diet.

    Science.gov (United States)

    Martínez-Micaelo, N; González-Abuín, N; Ardévol, A; Pinent, M; Petretto, E; Behmoaras, J; Blay, M

    2016-01-01

    Although the effect of genetic background on obesity-related phenotypes is well established, the main objective of this study is to determine the phenotypic responses to cafeteria diet (CAF) of two genetically distinct inbred rat strains and give insight into the molecular mechanisms that might be underlying. Lewis (LEW) and Wistar-Kyoto (WKY) rats were fed with either a standard or a CAF diet. The effects of the diet and the strain in the body weight gain, food intake, respiratory quotient, biochemical parameters in plasma as well as in the expression of genes that regulate leptin signalling were determined. Whereas CAF diet promoted weight gain in LEW and WKY rats, as consequence of increased energy intake, metabolic management of this energy surplus was significantly affected by genetic background. LEW and WKY showed a different metabolic profile, LEW rats showed hyperglycaemia, hypertriglyceridemia and high FFA levels, ketogenesis, high adiposity index and inflammation, but WKY did not. Leptin signalling, and specifically the LepRb-mediated regulation of STAT3 activation and Socs3 gene expression in the hypothalamus were inversely modulated by the CAF diet in LEW (upregulated) and WKY rats (downregulated). In the present study, we show evidence of gene-environment interactions in obesity exerted by differential phenotypic responses to CAF diet between LEW and WKY rats. Specifically, we found the leptin-signalling pathway as a divergent point between the strain-specific adaptations to diet.

  10. Elemental concentrations in kidney and liver of mice fed with cafeteria or standard diet determined by particle induced X-ray emission

    Energy Technology Data Exchange (ETDEWEB)

    Dimer Leffa, Daniela [Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806-000 Criciúma, SC (Brazil); Iochims dos Santos, Carla Eliete; Debastiani, Rafaela; Amaral, Livio; Yoneama, Maria Lucia; Ferraz Dias, Johnny [Ion Implantation Laboratory, Physics Institute, Federal University of Rio Grande do Sul, Porto Alegre (Brazil); Moraes Andrade, Vanessa, E-mail: vmoraesdeandrade@yahoo.com.br [Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806-000 Criciúma, SC (Brazil)

    2014-01-01

    The importance of trace elements in human health is well known and their main source is daily diet. Nowadays, one of the biggest issues is the presence of these micronutrients in levels much higher than required, leading to potential toxic effects. The aim of this work was to investigate the elemental content in organs of mice fed with cafeteria or standard diet using PIXE. Twelve male Swiss mice were divided into two groups: control group (standard chow) and cafeteria group (high-caloric diet). After 17 weeks, samples of different organs (kidney and liver) were collected and prepared for PIXE analysis. The Fe concentration in kidney and liver was statistically higher in animals that received the cafeteria diet (p < 0.001). The Al and Si kidney contents were significantly higher for cafeteria diet in relation to standard diet (p < 0.05). Moreover, the standard diet showed significant differences for Cl and K (p < 0.05) in comparison to cafeteria diet in kidney, and for P, S and Zn (p < 0.005) in liver.

  11. Elemental concentrations in kidney and liver of mice fed with cafeteria or standard diet determined by particle induced X-ray emission

    International Nuclear Information System (INIS)

    The importance of trace elements in human health is well known and their main source is daily diet. Nowadays, one of the biggest issues is the presence of these micronutrients in levels much higher than required, leading to potential toxic effects. The aim of this work was to investigate the elemental content in organs of mice fed with cafeteria or standard diet using PIXE. Twelve male Swiss mice were divided into two groups: control group (standard chow) and cafeteria group (high-caloric diet). After 17 weeks, samples of different organs (kidney and liver) were collected and prepared for PIXE analysis. The Fe concentration in kidney and liver was statistically higher in animals that received the cafeteria diet (p < 0.001). The Al and Si kidney contents were significantly higher for cafeteria diet in relation to standard diet (p < 0.05). Moreover, the standard diet showed significant differences for Cl and K (p < 0.05) in comparison to cafeteria diet in kidney, and for P, S and Zn (p < 0.005) in liver

  12. Cafeteria diet-induced obesity causes oxidative damage in white adipose.

    Science.gov (United States)

    Johnson, Amy R; Wilkerson, Matthew D; Sampey, Brante P; Troester, Melissa A; Hayes, D Neil; Makowski, Liza

    2016-04-29

    Obesity continues to be one of the most prominent public health dilemmas in the world. The complex interaction among the varied causes of obesity makes it a particularly challenging problem to address. While typical high-fat purified diets successfully induce weight gain in rodents, we have described a more robust model of diet-induced obesity based on feeding rats a diet consisting of highly palatable, energy-dense human junk foods - the "cafeteria" diet (CAF, 45-53% kcal from fat). We previously reported that CAF-fed rats became hyperphagic, gained more weight, and developed more severe hyperinsulinemia, hyperglycemia, and glucose intolerance compared to the lard-based 45% kcal from fat high fat diet-fed group. In addition, the CAF diet-fed group displayed a higher degree of inflammation in adipose and liver, mitochondrial dysfunction, and an increased concentration of lipid-derived, pro-inflammatory mediators. Building upon our previous findings, we aimed to determine mechanisms that underlie physiologic findings in the CAF diet. We investigated the effect of CAF diet-induced obesity on adipose tissue specifically using expression arrays and immunohistochemistry. Genomic evidence indicated the CAF diet induced alterations in the white adipose gene transcriptome, with notable suppression of glutathione-related genes and pathways involved in mitigating oxidative stress. Immunohistochemical analysis indicated a doubling in adipose lipid peroxidation marker 4-HNE levels compared to rats that remained lean on control standard chow diet. Our data indicates that the CAF diet drives an increase in oxidative damage in white adipose tissue that may affect tissue homeostasis. Oxidative stress drives activation of inflammatory kinases that can perturb insulin signaling leading to glucose intolerance and diabetes.

  13. Gamification of dietary decision-making in an elementary-school cafeteria.

    Science.gov (United States)

    Jones, Brooke A; Madden, Gregory J; Wengreen, Heidi J; Aguilar, Sheryl S; Desjardins, E Anne

    2014-01-01

    Despite the known health benefits of doing so, most US children do not consume enough fruits and vegetables (FV). School-based interventions can be effective in increasing FV consumption, but the most effective of these require that schools allocate their time, effort, and financial resources to implementing the program: expenditures that schools may be reluctant to provide in climates of academic accountability and economic austerity. The present demonstration project used a behaviorally based gamification approach to develop an intervention designed to increase FV consumption while minimizing material and labor costs to the school. During the intervention, the school (N = 180 students in grades K-8) played a cooperative game in which school-level goals were met by consuming higher-than-normal amounts of either fruit or vegetables (alternating-treatments experimental design). School-level consumption was quantified using a weight-based waste measure in the cafeteria. Over a period of 13 school days, fruit consumption increased by 66% and vegetable consumption by 44% above baseline levels. Use of an alternating-treatment time-series design with differential levels of FV consumption on days when fruit or vegetable was targeted for improvement supported the role of the intervention in these overall consumption increases. In post-intervention surveys, teachers rated the intervention as practical in the classroom and enjoyed by their students. Parent surveys revealed that children were more willing to try new FV at home and increased their consumption of FV following the intervention. These findings suggest that a behaviorally based gamification approach may prove practically useful in addressing concerns about poor dietary decision-making by children in schools. PMID:24718587

  14. Gamification of dietary decision-making in an elementary-school cafeteria.

    Directory of Open Access Journals (Sweden)

    Brooke A Jones

    Full Text Available Despite the known health benefits of doing so, most US children do not consume enough fruits and vegetables (FV. School-based interventions can be effective in increasing FV consumption, but the most effective of these require that schools allocate their time, effort, and financial resources to implementing the program: expenditures that schools may be reluctant to provide in climates of academic accountability and economic austerity. The present demonstration project used a behaviorally based gamification approach to develop an intervention designed to increase FV consumption while minimizing material and labor costs to the school. During the intervention, the school (N = 180 students in grades K-8 played a cooperative game in which school-level goals were met by consuming higher-than-normal amounts of either fruit or vegetables (alternating-treatments experimental design. School-level consumption was quantified using a weight-based waste measure in the cafeteria. Over a period of 13 school days, fruit consumption increased by 66% and vegetable consumption by 44% above baseline levels. Use of an alternating-treatment time-series design with differential levels of FV consumption on days when fruit or vegetable was targeted for improvement supported the role of the intervention in these overall consumption increases. In post-intervention surveys, teachers rated the intervention as practical in the classroom and enjoyed by their students. Parent surveys revealed that children were more willing to try new FV at home and increased their consumption of FV following the intervention. These findings suggest that a behaviorally based gamification approach may prove practically useful in addressing concerns about poor dietary decision-making by children in schools.

  15. Cafeteria diet-induced obesity causes oxidative damage in white adipose.

    Science.gov (United States)

    Johnson, Amy R; Wilkerson, Matthew D; Sampey, Brante P; Troester, Melissa A; Hayes, D Neil; Makowski, Liza

    2016-04-29

    Obesity continues to be one of the most prominent public health dilemmas in the world. The complex interaction among the varied causes of obesity makes it a particularly challenging problem to address. While typical high-fat purified diets successfully induce weight gain in rodents, we have described a more robust model of diet-induced obesity based on feeding rats a diet consisting of highly palatable, energy-dense human junk foods - the "cafeteria" diet (CAF, 45-53% kcal from fat). We previously reported that CAF-fed rats became hyperphagic, gained more weight, and developed more severe hyperinsulinemia, hyperglycemia, and glucose intolerance compared to the lard-based 45% kcal from fat high fat diet-fed group. In addition, the CAF diet-fed group displayed a higher degree of inflammation in adipose and liver, mitochondrial dysfunction, and an increased concentration of lipid-derived, pro-inflammatory mediators. Building upon our previous findings, we aimed to determine mechanisms that underlie physiologic findings in the CAF diet. We investigated the effect of CAF diet-induced obesity on adipose tissue specifically using expression arrays and immunohistochemistry. Genomic evidence indicated the CAF diet induced alterations in the white adipose gene transcriptome, with notable suppression of glutathione-related genes and pathways involved in mitigating oxidative stress. Immunohistochemical analysis indicated a doubling in adipose lipid peroxidation marker 4-HNE levels compared to rats that remained lean on control standard chow diet. Our data indicates that the CAF diet drives an increase in oxidative damage in white adipose tissue that may affect tissue homeostasis. Oxidative stress drives activation of inflammatory kinases that can perturb insulin signaling leading to glucose intolerance and diabetes. PMID:27033600

  16. Understanding the Functional Central Limit Theorems with Some Applications to Unit Root Testing with Structural Change

    Directory of Open Access Journals (Sweden)

    Juan Carlos Aquino

    2013-06-01

    Full Text Available The application of different unit root statistics is by now a standard practice in empirical work. Even when it is a practical issue, these statistics have complex nonstandard distributions depending on functionals of certain stochastic processes, and their derivations represent a barrier even for many theoretical econometricians. These derivations are based on rigorous and fundamental statistical tools which are not (very well known by standard econometricians. This paper aims to fill this gap by explaining in a simple way one of these fundamental tools: namely, the Functional Central Limit Theorem. To this end, this paper analyzes the foundations and applicability of two versions of the Functional Central Limit Theorem within the framework of a unit root with a structural break. Initial attention is focused on the probabilistic structure of the time series to be considered. Thereafter, attention is focused on the asymptotic theory for nonstationary time series proposed by Phillips (1987a, which is applied by Perron (1989 to study the effects of an (assumed exogenous structural break on the power of the augmented Dickey-Fuller test and by Zivot and Andrews (1992 to criticize the exogeneity assumption and propose a method for estimating an endogenous breakpoint. A systematic method for dealing with efficiency issues is introduced by Perron and Rodriguez (2003, which extends the Generalized Least Squares detrending approach due to Elliot et al. (1996. An empirical application is provided.

  17. Cafeteria diet-induced insulin resistance is not associated with decreased insulin signaling or AMPK activity and is alleviated by physical training in rats

    OpenAIRE

    Brandt, Nina; De Bock, Katrien; Richter, Erik A.; Hespel, Peter

    2010-01-01

    Brandt N, De Bock K, Richter EA, Hespel P. Cafeteria diet-induced insulin resistance is not associated with decreased insulin signaling or AMPK activity and is alleviated by physical training in rats. Am J Physiol Endocrinol Metab 299: E215-E224, 2010. First published May 18, 2010; doi:10.1152/ajpendo.00098.2010.-Excess energy intake via a palatable low-fat diet (cafeteria diet) is known to induce obesity and glucose intolerance in rats. However, the molecular mechanisms behind this adaptatio...

  18. Effets du régime cafeteria sur les marqueurs du statut oxyqanII antioxydant (sang, foie, muscle) chez la rate wistar au &de la ' gestation.

    OpenAIRE

    ATTARI, Faiza

    2014-01-01

    Résumé: Une suralimentation prolongée provoque une obésité avec installation des troubles K ' métaboliques. Le but de ce travail est de déterminer les effets du régime cafeteria, un régime hyperlipidique et hypercalorique, sur le métabolisme des lipides, des glucides et le statut oxydant/ antioxydant chez la rate pendant la gestation. Le régime cafeteria induit une obésité suite à une hyperphagie, associée à une augmentation du tissu adipeux, à une hyperglycémie, et une hype...

  19. Evaluation of Soil Flushing for Application to the Deep Vadose Zone in the Hanford Central Plateau

    Energy Technology Data Exchange (ETDEWEB)

    Truex, Michael J.; Oostrom, Martinus; Zhang, Z. F.; Carroll, Kenneth C.; Schramke, Janet A.; Wietsma, Thomas W.; Tartakovsky, Guzel D.; Gordon, Kathryn A.; Last, George V.

    2010-11-01

    Soil flushing was included in the Deep Vadose Zone Treatability Test Plan for the Hanford Central Plateau as a technology with the potential to remove contaminants from the vadose zone. Soil flushing operates through the addition of water, and if necessary an appropriate mobilizing agent, to mobilize contaminants and flush them from the vadose zone and into the groundwater where they are subsequently captured by a pump-and-treat system. There are uncertainties associated with applying soil flushing technology to contaminants in the deep vadose zone at the Hanford Central Plateau. The modeling and laboratory efforts reported herein are intended to provide a quantitative assessment of factors that impact water infiltration and contaminant flushing through the vadose zone and into the underlying groundwater. Once in the groundwater, capture of the contaminants would be necessary, but this aspect of implementing soil flushing was not evaluated in this effort. Soil flushing was evaluated primarily with respect to applications for technetium and uranium contaminants in the deep vadose zone of the Hanford Central Plateau.

  20. Cannabis, Cannabinoids, and Cerebral Metabolism: Potential Applications in Stroke and Disorders of the Central Nervous System.

    Science.gov (United States)

    Latorre, Julius Gene S; Schmidt, Elena B

    2015-09-01

    No compound has generated more attention in both the scientific and recently in the political arena as much as cannabinoids. These diverse groups of compounds referred collectively as cannabinoids have both been vilified due to its dramatic and potentially harmful psychotropic effects and glorified due to its equally dramatic and potential application in a number of acute and chronic neurological conditions. Previously illegal to possess, cannabis, the plant where natural form of cannabinoids are derived, is now accepted in a growing number of states for medicinal purpose, and some even for recreational use, increasing opportunities for more scientific experimentation. The purpose of this review is to summarize the growing body of literature on cannabinoids and to present an overview of our current state of knowledge of the human endocannabinoid system in the hope of defining the future of cannabinoids and its potential applications in disorders of the central nervous system, focusing on stroke. PMID:26238742

  1. Security central processing unit applications in the protection of nuclear facilities

    International Nuclear Information System (INIS)

    New or upgraded electronic security systems protecting nuclear facilities or complexes will be heavily computer dependent. Proper planning for new systems and the employment of new state-of-the-art 32 bit processors in the processing of subsystem reports are key elements in effective security systems. The processing of subsystem reports represents only a small segment of system overhead. In selecting a security system to meet the current and future needs for nuclear security applications the central processing unit (CPU) applied in the system architecture is the critical element in system performance. New 32 bit technology eliminates the need for program overlays while providing system programmers with well documented program tools to develop effective systems to operate in all phases of nuclear security applications

  2. Strategies for Reducing Energy Consumption in a Student Cafeteria in a Hot-Humid Climate: A Case Study

    Directory of Open Access Journals (Sweden)

    Mohammed Alhaji Mohammed

    2013-03-01

    Full Text Available Increasing attention is being given to energy consumption and potential for energy savings in public buildings in order to improve energy performance. Due to their size and functional requirements, public buildings especially cafeteria facilities tend to consume a significant amount of energy. Furthermore, due to their operational characteristics and construction pattern, unnecessary energy is likely to be used for maintaining acceptable indoor environmental quality. In this study, a student cafeteria at King Fahd University of Petroleum and Minerals, Saudi Arabia, was selected for the assessment of its energy performance and potential energy conservation opportunities. Energy simulation software Visual DOE 4.1 was used to develop an energy performance model for assessing various energy conservation measures pertinent to the building envelope and HVAC system design. Data required for setting up the model were gathered through simple energy audits. The architectural and mechanical drawings and the history of electrical consumption were collected. Various energy conservation strategies were then implemented including standards, single and combined energy conservation measures. These measures resulted in a combined design saving of 27.4%, the HVAC system saving 10.6%, implementation of standards saving about 16.7%, lighting 6.6%, equipment 2.6%, insulation 2.5% and glazing 1.4%. Based on these results, it is apparent that there is a significant potential for improving energy performance and justification to employ the suggested measures for achieving substantial energy savings and minimize energy consumption.

  3. Analysis of the Solar Resource Information Datasets for Thermal and/or electric Generation Using a Geographical Information System. Cases of Application: Central Cafeteria - University of the Valley, Cali Municipality and Farm {sup P}ozo Verde{sup ,} Jamundi Municipality , Cauca Valley, Colombia; Analisis de las Fuentes de Informacion sobre Recurso Solar para Generacion Termica y/o Electrica Empleando un Sistema de Informacion Geografica. Casos de Aplicacion: Cafeteria Central - Universidad del Valle, Municipio de Cali y Granja {sup P}ozo Verde{sup ,} Municipio de Jamundi, Valle del Cauca, Colombia

    Energy Technology Data Exchange (ETDEWEB)

    Dominguez, J.; Manrique, P. A.; Pinedo, I.

    2009-10-12

    In this report, two examples of renewable energy assessments based on Geographical Information Systems are presented. Several case studies have been carried out in the Valley of Cauca (Colombia), and one on them has been used to size a hybrid system. The results of this particular case study are presented in a second report. The aim of this document is analysing the different sources of data that could be used in the characterization of solar energy for electricity and electricity-heat use. With this purpose, data of two areas in Valley of Cauca obtained from the Atlas of Solar Radiation of Colombia, SWERA project and SSE-NASA have been compared. The data coming from these sources has been analysed using a Geographical Information System, and the conclusions are described along with cartographic and numeric products. These reports are the result of a collaboration established between Universidad del Valle (Colombia) and CIEMAT (Spain), and have been done by the author while his staying at our center included on his PhD program.

  4. Middle School Cafeteria Food Choice and Waste Prior to Implementation of Healthy, Hunger-Free Kids Act Changes in the National School Lunch Program

    Science.gov (United States)

    Connors, Priscilla; Bednar, Carolyn

    2015-01-01

    Purpose/Objectives: The study objective was to document choices of entrées, vegetables, fruits, grains/breads, and beverages on lunch trays and to determine the amount of each that was discarded after mealtime. Methods: A convenience sample of two urban middle school cafeterias in Texas participated in the study which took place in the 2010-2011…

  5. Effects of the cafeteria diet on the salivary glands of trained and sedentary Wistar rats - doi: 10.4025/actascibiolsci.v34i1.7473

    Directory of Open Access Journals (Sweden)

    Maria Raquel Marçal Natali

    2011-11-01

    Full Text Available The objective of this work was to study the effect of the aerobic physical training and the cafeteria diet introduced after weaning of Wistar rats and on the morphology of the main salivary glands (parotid, submandibular, sublingual. Male rats after weaning were subjected to the cafeteria diet or the standard rodent chow, and either performed aerobic physical training in a treadmill for 100 days, or did not performed any physical activity. Analyses were done considering the response in body weight, adipose tissues and salivary glands, and the data were submitted to statistical treatment (p < 0.05. The morphological and morphometric analyses of the salivary glands were performed through histological sections stained with hematoxylin and eosin. Despite the normophagic behavior, the rodents fed with the cafeteria diet became obese, with repercussions on parotid gland weight. However, this obesity and/or physical training did not influence the histological organization of the salivary glands. The morphometric analysis of the submandibular glands pointed out a reduction in the levels of serous acinar cells as an effect of the diet and physical training. In conclusion, the parotid and the submandibular glands alter themselves due to the nature and consistency of food present in the cafeteria diet as well as due to the aerobic physical training.

  6. An application-layer based centralized information access control for VPN

    Institute of Scientific and Technical Information of China (English)

    OUYANG Kai; ZHOU Jing-li; XIA Tao; YU Sheng-sheng

    2006-01-01

    With the rapid development of Virtual Private Network (VPN), many companies and organizations use VPN to implement their private communication. Traditionally, VPN uses security protocols to protect the confidentiality of data, the message integrity and the endpoint authentication. One core technique of VPN is tunneling, by which clients can access the internal servers traversing VPN. However, the tunneling technique also introduces a concealed security hole. It is possible that ifone vicious user can establish tunneling by the VPN server, he can compromise the internal servers behind the VPN server. So this paper presents a novel Application-layer based Centralized Information Access Control (ACIAC) for VPN to solve this problem.To implement an efficient, flexible and multi-decision access control model, we present two key techniques to ACIAC-the centralized management mechanism and the stream-based access control. Firstly, we implement the information center and the constraints/events center for ACIAC. By the two centers, we can provide an abstract access control mechanism, and the material access control can be decided dynamically by the ACIAC's constraint/event mechanism. Then we logically classify the VPN communication traffic into the access stream and the data stream so that we can tightly couple the features of VPN communication with the access control model. We also provide the design of our ACIAC prototype in this paper.

  7. E-business and its Application in Conditions of Central European Market

    Directory of Open Access Journals (Sweden)

    Naci Tolga Saruc

    2013-07-01

    Full Text Available Aim of this paper is highlighting possibilities in effective utilization of Information and Communication Technologies for supporting entrepreneurship (e-business for Small and Medium enterprises. The core research carried on for duration of twelve months covered analysis and following presentation of possibilities of practical utilization of e-business applications. Furthermore research was oriented towards innovative forms of marketing communication in Real Corporation conducting business in Central European market. Analyzing data on collected findings can add value towards gaining a significant competitive advantage in form of better understanding of real facts influencing entrepreneurship in principle. This can lead consequently to positive influence on corporate effectiveness in the environment of Small and Medium enterprises.

  8. Betweenness centrality and its applications from modeling traffic flows to network community detection

    Science.gov (United States)

    Ren, Yihui

    network and we demonstrate that the changes can propagate globally, affecting traffic several hundreds of miles away. Because of its principled nature, this method can inform many applications related to human mobility driven flows in spatial networks, ranging from transportation, through urban planning to mitigation of the effects of catastrophic events. In the second part of the thesis we focus on network deconstruction and community detection problems, both intensely studied topics in network science, using a weighted betweenness centrality approach. We present an algorithm that solves both problems efficiently and accurately and demonstrate that on both benchmark networks and data networks.

  9. Effects of long-term cycling between palatable cafeteria diet and regular chow on intake, eating patterns, and response to saccharin and sucrose.

    Science.gov (United States)

    Martire, Sarah I; Westbrook, R Fred; Morris, Margaret J

    2015-02-01

    When exposed to a diet containing foods that are rich in fat and sugar, rats eat to excess and gain weight. We examined the effects of alternating this diet with laboratory chow on intake of each type of diet, the eating elicited by a palatable food (biscuits), and the drinking elicited by sweet solutions that did (sucrose) or did not (saccharin) contain calories. Each week for 13 weeks, cycled rats were provided with the cafeteria diet for three successive days/nights and the chow diet for the remaining four days/nights, whereas other rats received continuous access to either the cafeteria or the chow diets. On each of the 13 weeks, cycled rats ate more across the first 24 hour exposure to the cafeteria diet than rats continuously fed this diet. In contrast, cycled rats ate less across the first 24 hour exposure to the chow diet than rats continuously fed this diet and ate less when presented a novel palatable biscuit than chow-fed rats. The three groups exhibited similar licks per cluster to saccharin, but cafeteria-fed and cycled rats showed fewer clusters than chow-fed rats. In contrast, chow-fed rats and cycled rats exhibited more licks per cluster to sucrose than cafeteria-fed rats, but all three groups had a similar number of clusters. The results were discussed in relation to the effects of diet cycling on eating patterns, body weight, and 'wanting' and 'liking'. These findings with rats may have important implications for yo-yo dieting in people.

  10. Chronic intake of a cafeteria diet and subsequent abstinence. Sex-specific effects on gene expression in the mesolimbic reward system.

    Science.gov (United States)

    Ong, Zhi Yi; Wanasuria, Ayumi F; Lin, Mark Z P; Hiscock, Jennifer; Muhlhausler, Beverly S

    2013-06-01

    Studies examining the impact of chronic palatable food intake on the mesolimbic reward system have been conducted almost exclusively in males. This study aimed to determine the effects of chronic intake of a palatable cafeteria diet and subsequent abstinence on fat mass, food intake and key gene expression of the mesolimbic reward system in both males and females. Albino Wistar rats were fed for 8 weeks on standard chow (Control, n=5 males, 5 females) or cafeteria diet (CD; n=16 males, 16 females). The cafeteria diet was then removed from a subset of CD rats for 72 h (CD-Withdrawal group, CD-W). The nucleus accumbens (NAc) was isolated and mRNA expression of tyrosine hydroxylase (TH), dopamine active transporter (DAT), D1 and D2 dopamine receptors, and μ-opioid receptor determined by qRT-PCR. Chronic cafeteria diet intake increased fat mass in all CD rats but body weight and chow intake were reduced during the period of cafeteria diet abstinence. TH mRNA was reduced in male CD and CD-W rats, but increased in female CD and CD-W rats. D1 mRNA was reduced in CD and CD-W females, but increased in CD males, compared to Controls. μ-opioid receptor expression was reduced in CD and CD-W males but not females. These data highlight the importance of investigating sex differences in the neurobiological response to palatable food intake and the need for future studies in this area to include both sexes.

  11. Application of pesticide transport model for simulating diazinon runoff in California’s central valley

    Science.gov (United States)

    Joyce, Brian A.; Wallender, Wesley W.; Mailapalli, Damodhara R.

    2010-12-01

    Dormant spray application of pesticides to almond and other stone fruit orchards is the main source of diazinon during the winter in California's central valley. Understanding the pesticide transport and the tradeoffs associated with the various management practices is greatly facilitated by the use of physically-based contaminant transport models. In this study, performance of Joyce's et al. (2008) pesticide transport model was evaluated using experimental data collected from two ground treatments such as resident vegetation and bare soil. The model simulation results obtained in calibration and validation process were analyzed for pesticide concentration and total load. The pesticide transport model accurately predicted the pesticide concentrations and total load in the runoff from bare field and was capable of simulating chemical responses to rainfall-runoff events. In case of resident vegetation, the model results exhibited a larger range of variation than was observed in the bare soil simulations due to increased model parameterization with the addition of foliage and thatch compartments. Furthermore, the model was applied to study the effect of runoff lag time, extent of crop cover, organic content of soil and post-application irrigation on the pesticide peak concentration and total load. Based on the model results, recommendations were suggested to growers prior to implementing certain management decisions to mitigate diazinon transport in the orchard's spray runoff.

  12. A escola promovendo hábitos alimentares saudáveis: uma proposta metodológica de capacitação para educadores e donos de cantina escolar Promotion of healthy eating habits by schools: a methodological proposal for training courses for educators and school cafeteria owners

    Directory of Open Access Journals (Sweden)

    Bethsáida de Abreu Soares Schmitz

    2008-01-01

    Full Text Available O projeto A Escola Promovendo Hábitos Alimentares Saudáveis estimula, desde 2001 no Distrito Federal, Brasil, a formação de bons hábitos alimentares na comunidade escolar, no contexto da promoção de estilos de vida saudáveis e prevenção das doenças crônicas não- transmissíveis. Este trabalho apresenta e avalia uma metodologia desenvolvida em 2006, para capacitação de educadores do ensino infantil e fundamental até a 4ª série e donos de cantina escolar. As oficinas tiveram aulas expositivas, atividades práticas, jogos educativos, entre outros. Como indicadores de avaliação analisaram-se itens relacionados à ampliação e aplicabilidade dos conhecimentos, além da implantação dos 10 passos da cantina escolar saudável. As atividades pedagógicas propostas foram verificadas pela análise dos portfólios dos educadores. A avaliação geral foi positiva, houve ampliação dos conhecimentos (p The project entitled Promotion of Health Eating Habits by Schools, operating in the Federal District of Brazil since 2001, encourages good eating habits in the school community within the context of promoting healthy lifestyles and preventing chronic non-communicable diseases. The current article presents and analyzes a methodology to train preschool and elementary educators and school cafeteria owners. The workshops included theoretical classes, practical activities, and educational games and were evaluated on the basis of expansion and applicability of knowledge, in addition to implementation of the 10 steps to a healthy school cafeteria. The proposed pedagogical activities were verified by an analysis of the teachers' workshop folders. The overall evaluation was positive, with expansion of knowledge (p < 0.05 among participants for the three workshop modules. The objectives laid out in the workshop folders were reached by 44% of the teachers. In the implementation of the healthy cafeteria, positive results were observed when comparing

  13. INCA-CE: a Central European initiative in nowcasting severe weather and its applications

    Science.gov (United States)

    Kann, A.; Pistotnik, G.; Bica, B.

    2012-04-01

    The INCA-CE (Integrated Nowcasting through Comprehensive Analysis - Central Europe) project aims at implementing a transnational weather information system as well as applications for different socio-economic sectors to reduce risks of major economic damage and loss of life caused by severe weather. Civil protection and also stakeholders from economic sectors are in a growing need of accurate and reliable short-term weather forecasts. Within INCA-CE, a state-of-the art nowcasting system (INCA) is implemented at weather services throughout the European Union's CE (Central Europe) Programme Area, providing analyses and short term forecasts to the aforementioned end-users. In a coherent approach, the INCA (Integrated Nowcasting through Comprehensive Analysis) system will be adapted for implementation and use in a number of partner countries. Within transregional working groups, the gap between short-term weather information and its downstream activities in hydrological disaster management, civil protection and road management will be bridged and best practice management and measure plans will be produced. A web-based platform for outreach to related socio-economic sectors will initiate and foster a dialogue between weather services and further stakeholders like tourism or the insurance sector, flood authorities for disaster management, and the construction industry for cost-efficient scheduling and planning. Furthermore, the project will produce a compact guideline for policy makers on how to combine structural development aspects with these new features. In the present paper, an outline of the project implementation, a short overview about the INCA system and two case studies on precipitation nowcasts will be given. Moreover, directions for further developments both within the INCA system and the INCA-CE project will be pointed out.

  14. Application of dental nanomaterials: potential toxicity to the central nervous system

    Directory of Open Access Journals (Sweden)

    Feng X

    2015-05-01

    Full Text Available Xiaoli Feng,1 Aijie Chen,1 Yanli Zhang,1 Jianfeng Wang,2 Longquan Shao,1 Limin Wei2 1Nanfang Hospital, Southern Medical University, Guangzhou, 2School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, People’s Republic of China Abstract: Nanomaterials are defined as materials with one or more external dimensions with a size of 1–100 nm. Such materials possess typical nanostructure-dependent properties (eg, chemical, biological, optical, mechanical, and magnetic, which may differ greatly from the properties of their bulk counterparts. In recent years, nanomaterials have been widely used in the production of dental materials, particularly in light polymerization composite resins and bonding systems, coating materials for dental implants, bioceramics, endodontic sealers, and mouthwashes. However, the dental applications of nanomaterials yield not only a significant improvement in clinical treatments but also growing concerns regarding their biosecurity. The brain is well protected by the blood–brain barrier (BBB, which separates the blood from the cerebral parenchyma. However, in recent years, many studies have found that nanoparticles (NPs, including nanocarriers, can transport through the BBB and locate in the central nervous system (CNS. Because the CNS may be a potential target organ of the nanomaterials, it is essential to determine the neurotoxic effects of NPs. In this review, possible dental nanomaterials and their pathways into the CNS are discussed, as well as related neurotoxicity effects underlying the in vitro and in vivo studies. Finally, we analyze the limitations of the current testing methods on the toxicological effects of nanomaterials. This review contributes to a better understanding of the nano-related risks to the CNS as well as the further development of safety assessment systems. Keywords: dental, nanomaterials, central nervous system, toxicity, testing methods, risk assessment

  15. Behavioral characterization of a model of differential susceptibility to obesity induced by standard and personalized cafeteria diet feeding.

    Science.gov (United States)

    Gac, L; Kanaly, V; Ramirez, V; Teske, J A; Pinto, M P; Perez-Leighton, C E

    2015-12-01

    Despite the increase in obesity prevalence over the last decades, humans show large inter-individual variability for susceptibility to diet-induced obesity. Understanding the biological basis of this susceptibility could identify new therapeutic alternatives against obesity. We characterized behavioral changes associated with propensity to obesity induced by cafeteria (CAF) diet consumption in mice. We show that Balb/c mice fed a CAF diet display a large inter-individual variability in susceptibility to diet-induced obesity, such that based on changes in adiposity we can classify mice as obesity prone (OP) or obesity resistant (OR). Both OP and OR were hyperphagic relative to control-fed mice but caloric intake was similar between OP and OR mice. In contrast, OR had a larger increase in locomotor activity following CAF diet compared to OP mice. Obesity resistant and prone mice showed similar intake of sweet snacks, but OR ate more savory snacks than OP mice. Two bottle sucrose preference tests showed that OP decreased their sucrose preference compared to OR mice after CAF diet feeding. Finally, to test the robustness of the OR phenotype in response to further increases in caloric intake, we fed OR mice with a personalized CAF (CAF-P) diet based on individual snack preferences. When fed a CAF-P diet, OR increased their calorie intake compared to OP mice fed the standard CAF diet, but did not reach adiposity levels observed in OP mice. Together, our data show the contribution of hedonic intake, individual snack preference and physical activity to individual susceptibility to obesity in Balb/c mice fed a standard and personalized cafeteria-style diet.

  16. Laser photobiomodulation as an adjunct of the wound healing impairment of rats exposed to a cafeteria diet

    Science.gov (United States)

    Uzeda, V.; Paraguassu, G. M.; Dos Santos, J. N.; Ramalho, M. J.; Rodriguez, T. T.; Ramalho, L. M. P.

    2014-02-01

    Obesity is associated to a delayed wound healing and prolonged inflammatory phase. Laser light has shown positive results in the photobiomodulation of tissue repair; however, its use associated with systemic disorders such as obesity is still little explored in the literature. The aim of this study was to validate an experimental system for studying weight gaining by consuming a high fat diet called "cafeteria diet" (CD) for the induction of obesity. Forty-eight rats were weaned, divided into two experimental groups: standard diet (SD) and Cafeteria Diet (CD). Free feeding was carried out during 20 weeks and the mass gaining was accompanied. After general anesthesia standardized surgical wounds were created (1cm2) in the dorsal midline region of each animal. Both groups (SD; CD) were divided into 2 subgroups of 12 animals, G1 and G3 (non-irradiated) and G2 and G4 (irradiated). The irradiation protocols (λ660 nm, 40 mW, CW; 24 J/cm2) started immediately after surgery and were repeated every other day during 14 days. The rats were killed at the 8th or 15th days after surgery. The abdominal fat was removed and weighed to verify the success of the induction technique. The specimens were taken and routinely processed histology (hematoxylin/eosin) was performed. It was concluded that the ingestion of fast-food increased abdominal fat in rats and modified the inflammatory pattern of the healing. Laser phototherapy in the parameters employed decreased inflammatory intensity quickening wound healing in obese rats.

  17. Correlation between centrality metrics and their application to the opinion model

    NARCIS (Netherlands)

    Li, C.; Li, Q.; Van Mieghem, P.F.A.; Stanley, H.E.; Wang, H.

    2015-01-01

    In recent decades, a number of centrality metrics describing network properties of nodes have been proposed to rank the importance of nodes. In order to understand the correlations between centrality metrics and to approximate a high-complexity centrality metric by a strongly correlated low-complexi

  18. Application of ICT (Information and Communication Technology) in the Management of Universities in the North-Central State of Nigeria

    Science.gov (United States)

    Oboegbulem, Angie Ijeoma; Godwin, Ochai

    2013-01-01

    This study investigated the application of ICT (information and communication technology) in the management of universities in the north-central Nigeria. The study was a descriptive survey. The population of the study comprised 1,294 respondents in federal and state universities (763 in federal and 531 in state universities). The sample size…

  19. Improved high temperature solar absorbers for use in Concentrating Solar Power central receiver applications.

    Energy Technology Data Exchange (ETDEWEB)

    Stechel, Ellen Beth; Ambrosini, Andrea; Hall, Aaron Christopher; Lambert, Timothy L.; Staiger, Chad Lynn; Bencomo, Marlene

    2010-09-01

    Concentrating solar power (CSP) systems use solar absorbers to convert the heat from sunlight to electric power. Increased operating temperatures are necessary to lower the cost of solar-generated electricity by improving efficiencies and reducing thermal energy storage costs. Durable new materials are needed to cope with operating temperatures >600 C. The current coating technology (Pyromark High Temperature paint) has a solar absorptance in excess of 0.95 but a thermal emittance greater than 0.8, which results in large thermal losses at high temperatures. In addition, because solar receivers operate in air, these coatings have long term stability issues that add to the operating costs of CSP facilities. Ideal absorbers must have high solar absorptance (>0.95) and low thermal emittance (<0.05) in the IR region, be stable in air, and be low-cost and readily manufacturable. We propose to utilize solution-based synthesis techniques to prepare intrinsic absorbers for use in central receiver applications.

  20. Applicability assessment of central and solar hot water systems integration in Serbia

    Directory of Open Access Journals (Sweden)

    Kljajić Miroslav V.

    2012-01-01

    Full Text Available Energy systems for consumers’ supply with sanitary hot water (SHW can be considered as a separate category of the system with many similar functions, performances and integral elements. This similarity of energy systems for SHW supply and the way in which they are used enable systemic planning, proposing and undertaking measures for improvements and advancements. This is possible not only by the reconstruction and modernization of existing technological solutions but also by their replacement with new, modern and more efficient solutions. The basic idea and the aim of this paper is the development of a concept for integrated and upgraded system of SHW supply for different types of buildings from residential to more complex buildings intended for different purposes. The analysis is based on the application of a systemic approach adapted to the conditions in urban communities and includes only modern but commercial technologies. This paper presents the results of a net energy analysis of integrated central and solar hot water supply system and compares it with the conventional sanitary hot water system in the City of Novi Sad, Serbia. The proposed methodology is demonstrated through a simulation example. It is shown that 23% reduction in the total system’s costs can be achieved as compared to the existing solution. Also, the methodology is applied to a residential block as a unit and obtained results indicate that investments in the development and construction of integrated systems are justified.

  1. Cafeteria diet-induced insulin resistance is not associated with decreased insulin signaling or AMPK activity and is alleviated by physical training in rats

    DEFF Research Database (Denmark)

    Brandt, Nina; De Bock, Katrien; Richter, Erik;

    2010-01-01

    counteracted by training. In the perfused hindlimb, insulin-stimulated glucose transport in red gastrocnemius muscle was completely abolished in CAF and rescued by exercise training. Apart from a tendency toward an approximately 20% reduction in both basal and insulin-stimulated Akt Ser(473) phosphorylation (P......) among the groups. In conclusion, surplus energy intake of a palatable but low-fat cafeteria diet resulted in obesity and insulin resistance that was rescued by exercise training. Interestingly, insulin resistance was not accompanied by major defects in the insulin-signaling cascade or in altered AMPK......Excess energy intake via a palatable low-fat diet (cafeteria diet) is known to induce obesity and glucose intolerance in rats. However, the molecular mechanisms behind this adaptation are not known, and it is also not known whether exercise training can reverse it. Male Wistar rats were assigned to...

  2. Process evaluation of two environmental nutrition programmes and an educational nutrition programme conducted at supermarkets and worksite cafeterias in the Netherlands

    OpenAIRE

    Steenhuis, I H M; van Assema, Patricia; Reubsaet, A.; Kok, Gerjo

    2004-01-01

    textabstractThis article describes the process evaluation of two environmental programs and a educational nutrition program, implemented at supermarkets and worksite cafeterias. Studies conducted earlier, indicated that the programs had no effect on consumers’ eating behavior. Consequently, the more specific purpose of the present study was to identify explanations for the ineffectiveness of the programs and to formulate recommendations for future programs. Materials and Methods The environme...

  3. Evidences of Basal Lactate Production in the Main White Adipose Tissue Sites of Rats. Effects of Sex and a Cafeteria Diet

    OpenAIRE

    Sofía Arriarán; Silvia Agnelli; David Sabater; Xavier Remesar; José Antonio Fernández-López; Marià Alemany

    2015-01-01

    Female and male adult Wistar rats were fed standard chow or a simplified cafeteria diet for one month. Then, the rats were killed and the white adipose tissue (WAT) in four sites: perigonadal, retroperitoneal, mesenteric and subcutaneous (inguinal) were sampled and frozen. The complete WAT weight in each site was measured. Gene expression analysis of key lipid and glucose metabolism enzymes were analyzed, as well as tissue and plasma lactate and the activity of lactate dehydrogenase. Lactate ...

  4. Statistical sulcal shape comparisons: application to the detection of genetic encoding of the central sulcus shape

    DEFF Research Database (Denmark)

    Le Goualher, G; Argenti, A.M.; Duyme, M;

    2000-01-01

    encoding. When applied to real data, this study highlighted genetic constraints on the shape of the central sulcus. We found from 10 pairs of monozygotic twins that the intrapair modal distance of the central sulcus was significantly smaller than the interpair modal distance, for both the left central...... sulcus (Z = -2.66; P sulcus (Z = -2.26; P sulcus shape were confirmed by applying the same experiment to 10 pairs of normal young individuals (Z = -1.39; Z = -0.63, i.e., values not significant at the P

  5. A Gis method for geodetic applications: the central Apennine Geodetic Network (GeoNetGis)

    OpenAIRE

    Cristofoletti, P.; Istituto Nazionale di Geofisica e Vulcanologia, Sezione CNT, Roma, Italia; Esposito, A.; Istituto Nazionale di Geofisica e Vulcanologia, Sezione CNT, Roma, Italia; Anzidei, M.; Istituto Nazionale di Geofisica e Vulcanologia, Sezione CNT, Roma, Italia

    2006-01-01

    To geophysical research and monitor crustal deformation in seismic and volcanic areas, a Geodetic Geographical Information System has been developed (GeoNetGIS). We applied our geodetic oriented GIS to a new GPS network recently set up and surveyed in the Central Apennine region. The Central Apennine Geodetic Network (CA-GeoNet) consists in 130 stations with an average grid of 5 km, covering the main seismogenetic structures of the area. Management and mapping GP...

  6. Correlation between centrality metrics and their application to the opinion model

    CERN Document Server

    Li, Cong; Van Mieghem, Piet; Stanley, H Eugene; Wang, Huijuan

    2014-01-01

    In recent decades, a number of centrality metrics describing network properties of nodes have been proposed to rank the importance of nodes. In order to understand the correlations between centrality metrics and to approximate a high-complexity centrality metric by a strongly correlated low-complexity metric, we ?first study the correlation between centrality metrics in terms of their Pearson correlation coefficient and their similarity in ranking of nodes. In addition to considering the widely used centrality metrics, we introduce a new centrality measure, the degree mass. The m order degree mass of a node is the sum of the weighted degree of the node and its neighbors no further than m hops away. We find that the B_{n}, the closeness, and the components of x_{1} are strongly correlated with the degree, the 1st-order degree mass and the 2nd-order degree mass, respectively, in both network models and real-world networks. We then theoretically prove that the Pearson correlation coefficient between x_{1} and th...

  7. Farmer evaluation of phosphorus fertilizer application to annual legumes in Chisepo, Central Malawi

    NARCIS (Netherlands)

    Kamanga, B.C.G.; Whitbread, A.M.; Wall, P.; Waddington, S.R.; Almekinders, C.J.M.; Giller, K.E.

    2010-01-01

    Building from the perception that farmers have an intimate knowledge of their local environment, production problems, crop priorities and criteria for evaluation, an on-farm experiment was conducted with farmers in 2003/4 in Chisepo, central Malawi, to evaluate the response of six annual legumes to

  8. Application of Canal Automation at the Central Arizona Irrigation and Drainage District

    Science.gov (United States)

    The Central Arizona Irrigation and Drainage District (CAIDD) began delivering water to users in 1987. Although designed for automatic control, the system was run manually until a homemade SCADA (Supervisory Control and Data Acquisition) system was developed by a district employee. In 2002, problem...

  9. Development and application of the decision support system for municipal solid waste management in central Taiwan.

    Science.gov (United States)

    Chang, Yao-Jen; Lin, Min-Der

    2013-05-01

    Municipal solid waste management (MSWM) is an important, practical and challenging environmental subject. The processes of a MSWM system include household collection, transportation, treatment, material recycling, compost and disposal. A regional program of MSWM is more complicated owing to the involvement of multi-municipality and multi-facility issues. Therefore, an effective decision support system capable of solving regional MSWM problems is necessary for decision-makers. This article employs linear programming techniques to establish a MSWM decision support system (MSWM-DSS) that is able to determine the least costs of regional MSWM strategies. The results of investigating a real-world case in central Taiwan indicate that a regional program is more economical and efficient. For the redeployment of MSW streams, the relatively least cost of operation for the MSWM system can still be achieved through the re-estimation of the MSWM-DSS. This tool and results are useful for MSWM policy-making in central Taiwan.

  10. Central Colorado Assessment Project - Application of integrated geologic, geochemical, biologic, and mineral resource studies

    Science.gov (United States)

    Klein, T.L.; Church, S.E.; Caine, J.S.; Schmidt, T.S.; deWitt, E.H.

    2008-01-01

    Central Colorado is one of the fastest-growing regions in the Western United States. Population along the Front Range increased more than 30 percent between 1990 and 2000 (http://www.demographia.com/db-metro3newworld.htm) with some counties within the study area, such as Park County, experiencing greater than 100-percent growth (http://www.censusscope.org/us/s8/rank_popl_growth.html). This growth has caused tremendous demand for natural resources and has created challenging land-management issues related to the interface between wilderness and urban expansion. Management of this wilderness/urban interface will benefit from current digital geoscience information collected by the U.S. Geological Survey (USGS) Central Colorado Assessment Project that began in 2003. Approximately 20,800 square miles (53,800 km2) of land divided almost equally between the public and private sectors were part of the assessment.

  11. Central Nervous System Disease in Hematological Malignancies: Historical Perspective and Practical Applications

    OpenAIRE

    Pui, Ching-Hon; Thiel, Eckhard

    2009-01-01

    Acute lymphoblastic leukemia (ALL) 5-year survival rates are approaching 90% in children and 50% in adults who are receiving contemporary risk-directed treatment protocols. Current efforts focus not only on further improving cure rate but also on patient quality of life. Hence, all protocols decrease or limit the use of cranial irradiation as central nervous system (CNS)-directed therapy, even in patients with high-risk presenting features, such as the presence of leukemia cells in the cerebr...

  12. Central limit theorems for directional and linear random variables with applications

    OpenAIRE

    García-Portugués, Eduardo; Crujeiras, Rosa M.; González-Manteiga, Wenceslao

    2014-01-01

    A central limit theorem for the integrated squared error of the directional-linear kernel density estimator is established. The result enables the construction and analysis of two testing procedures based on squared loss: a nonparametric independence test for directional and linear random variables and a goodness-of-fit test for parametric families of directional-linear densities. Limit distributions for both test statistics, and a consistent bootstrap strategy for the goodness-of-fit test, a...

  13. Identification of a nutrient-sensing transcriptional network in monocytes by using inbred rat models on a cafeteria diet

    Science.gov (United States)

    Martínez-Micaelo, Neus; González-Abuín, Noemi; Terra, Ximena; Ardévol, Ana; Pinent, Montserrat; Petretto, Enrico; Blay, Mayte

    2016-01-01

    ABSTRACT Obesity has reached pandemic levels worldwide. The current models of diet-induced obesity in rodents use predominantly high-fat based diets that do not take into account the consumption of variety of highly palatable, energy-dense foods that are prevalent in Western society. We and others have shown that the cafeteria (CAF) diet is a robust and reproducible model of human metabolic syndrome with tissue inflammation in the rat. We have previously shown that inbred rat strains such as Wistar Kyoto (WKY) and Lewis (LEW) show different susceptibilities to CAF diets with distinct metabolic and morphometric profiles. Here, we show a difference in plasma MCP-1 levels and investigate the effect of the CAF diet on peripheral blood monocyte transcriptome, as powerful stress-sensing immune cells, in WKY and LEW rats. We found that 75.5% of the differentially expressed transcripts under the CAF diet were upregulated in WKY rats and were functionally related to the activation of the immune response. Using a gene co-expression network constructed from the genes differentially expressed between CAF diet-fed LEW and WKY rats, we identified acyl-CoA synthetase short-chain family member 2 (Acss2) as a hub gene for a nutrient-sensing cluster of transcripts in monocytes. The Acss2 genomic region is significantly enriched for previously established metabolism quantitative trait loci in the rat. Notably, monocyte expression levels of Acss2 significantly correlated with plasma glucose, triglyceride, leptin and non-esterified fatty acid (NEFA) levels as well as morphometric measurements such as body weight and the total fat following feeding with the CAF diet in the rat. These results show the importance of the genetic background in nutritional genomics and identify inbred rat strains as potential models for CAF-diet-induced obesity. PMID:27483348

  14. Experimental studies on the impact of ASE noise of single-channel optical amplifiers in central office applications

    Institute of Scientific and Technical Information of China (English)

    zheng zheng(郑铮)

    2004-01-01

    We identified the amplified spontaneous emission-amplified spontaneous emission (ASE-ASE) beat noise from the semiconductor optical amplifier, which has been overlooked in previous studies, as a cause of severe system penalties when it was used to provide single-channel amplification in a dynamic central office environment through experimental studies. Our results pointed out that the ASE-ASE beat noise of the optical amplifier, other than its gain and noise figure, has to be considered to correctly predict its performance in these new applications.

  15. Application of a Central Composite Design for the Study of NOx Emission Performance of a Low NOx Burner

    OpenAIRE

    Marcin Dutka; Mario Ditaranto; Terese Løvås

    2015-01-01

    In this study, the influence of various factors on nitrogen oxides (NOx) emissions of a low NOx burner is investigated using a central composite design (CCD) approach to an experimental matrix in order to show the applicability of design of experiments methodology to the combustion field. Four factors have been analyzed in terms of their impact on NOx formation: hydrogen fraction in the fuel (0%–15% mass fraction in hydrogen-enriched methane), amount of excess air (5%–30%), burner head posit...

  16. Application of solar energy in heating and cooling of residential buildings under Central Asian conditions

    OpenAIRE

    Usmonov Shukhrat Zaurovich

    2014-01-01

    Solar radiation is the main source of thermal energy for almost all the processes developing in the atmosphere, hydrosphere, and biosphere. The total duration of sunshine in Tajikistan ranges from 2100 to 3170 hours per year. Solar collectors can be mounted on the roof of a house after its renovation and modernization. One square meter of surface area in Central Asia accounts for up to 1600 kW/h of solar energy gain, whilst the average gain is 1200 kW/h. Active solar thermal systems are able ...

  17. The application of Kyoto Protocol in Italy: role and required synergies between central and regional administrations

    Directory of Open Access Journals (Sweden)

    Pilli R

    2007-01-01

    Full Text Available According to art. 3.3 of the Kyoto Protocol, Parties included in Annex I shall report the net changes in greenhouse gas emissions by sources and removals by sinks resulting from afforestation, reforestation and deforestation activities. To assess these activities, Italy has to define methods to estimate land use change occurring after 31 December 1989. On the other hand, Italy elected forest management as additional human-induced activity to attain the goals of reduction of greenhouse gas emissions. The paper considers the key-role that central and regional Administrations may have in order to solve some specific problems regarding data collection and management issues.

  18. Application of Central Upwind Scheme for Solving Special Relativistic Hydrodynamic Equations.

    Directory of Open Access Journals (Sweden)

    Muhammad Yousaf

    Full Text Available The accurate modeling of various features in high energy astrophysical scenarios requires the solution of the Einstein equations together with those of special relativistic hydrodynamics (SRHD. Such models are more complicated than the non-relativistic ones due to the nonlinear relations between the conserved and state variables. A high-resolution shock-capturing central upwind scheme is implemented to solve the given set of equations. The proposed technique uses the precise information of local propagation speeds to avoid the excessive numerical diffusion. The second order accuracy of the scheme is obtained with the use of MUSCL-type initial reconstruction and Runge-Kutta time stepping method. After a discussion of the equations solved and of the techniques employed, a series of one and two-dimensional test problems are carried out. To validate the method and assess its accuracy, the staggered central and the kinetic flux-vector splitting schemes are also applied to the same model. The scheme is robust and efficient. Its results are comparable to those obtained from the sophisticated algorithms, even in the case of highly relativistic two-dimensional test problems.

  19. Integration of a central protein repository into a standard data processing application for mining proteomics data

    DEFF Research Database (Denmark)

    Fritzemeier, Kai; Kristensen, Jakob; Larsen, Martin Røssel;

    efficient data mining and categorizing of large data sets. Methods All samples were analyzed on an Orbitrap mass Spectrometer coupled to a nano Easy LC. The proteomics repository database is built using the Sun Java technology and the Microsoft mySQL database technology for optimal performance. Proteome......Novel Aspect All major protein repositories integrated into a central domain for direct analyses and interpretation in a standard proteomics data analysis software. Introduction Modern proteomics must face the challenge of performing bioinformatics analysis and comparison of large datasets....... It is a time consuming and at times nearly impossible task to distinguish known proteins from novel proteins in these data sets without proper annotation and comparison with literature sources. Tools are needed that can handle the complexity of these data including: redundancy (same protein but different...

  20. Risk of hypertension in Yozgat Province, Central Anatolia: application of Framingham Hypertension Prediction Risk Score.

    Science.gov (United States)

    Kilic, M; Ede, H; Kilic, A I

    2016-07-10

    The aim of this cross-sectional study was to estimate the risk of hypertension in 1106 Caucasian individuals aged 20-69 years in Yozgat Province, using the Framingham Hypertension Risk Prediction Score (FHRPS). According to FHRPS, average risk of developing hypertension over 4 years was 6.2%. The participants were classified into low- (10%) risk groups. The percentage of participants that fell into these groups was 59.4%, 19.8% and 20.8% respectively. The proportion of participants in the high-risk group was similar to the 4-year incidence of hypertension (21.3%) in the Turkish population. Regression analysis showed that high salt consumption and low educational level significantly increased the risk of hypertension. Economic level, fat consumption, life satisfaction, physical activity, and fruit and vegetable consumption were not correlated with risk of hypertension. This study shows that FHRPS can also be used for predicting risk of hypertension in Central Anatolia.

  1. Dynamic disturbance rejection controllers for neutral time delay systems with application to a central heating system

    Institute of Scientific and Technical Information of China (English)

    KOUMBOULIS Fotis N.; KOUVAKAS Nikolaos D.; PARASKEVOPOULOS Paraskevas N.

    2009-01-01

    In the present paper the problem of disturbance rejection of single input-single output neutral time delay systems with multiple measurable disturbances is solved via dynamic controllers. In particular, the general form of the controller matrices is presented, while the necessary and sufficient conditions for the controller to be realizable are offered. The proposed technique is applied to a test case neutral time delay central heating system. In particular, the nonlinear model of the plant and its linearized approximation are presented. Based on the linearized model, a two-stage controller is designed in order to regulate the room temperature and the boiler effluent temperature. The performance of the closed loop system is investigated through computational experiments.

  2. Fractal characterization of rain-gauge networks and precipitations: an application in Central Italy

    CERN Document Server

    Capecchi, Valerio; Melani, Samantha; Morabito, Marco; Politi, Paolo

    2011-01-01

    The measuring stations of a geophysical network are often spatially distributed in an inhomogeneous manner. The areal inhomogeneity can be well characterized by the fractal dimension D_H of the network, which is usually smaller than the euclidean dimension of the surface, this latter equal to 2. The resulting dimensional deficit, (2-D_H), is a measure of precipitating events which cannot be detected by the network. The aim of the present study is to estimate the fractal dimension of a rain-gauge network in Tuscany (Central Italy) and to relate its dimension to the dimensions of daily rainfall events detected by a mixed satellite/radar methodology. We find that D_H = 1.85, while typical summer precipitations are characterized by a dimension much greater than the dimensional deficit 0.15.

  3. Risk of hypertension in Yozgat Province, Central Anatolia: application of Framingham Hypertension Prediction Risk Score.

    Science.gov (United States)

    Kilic, M; Ede, H; Kilic, A I

    2016-04-01

    The aim of this cross-sectional study was to estimate the risk of hypertension in 1106 Caucasian individuals aged 20-69 years in Yozgat Province, using the Framingham Hypertension Risk Prediction Score (FHRPS). According to FHRPS, average risk of developing hypertension over 4 years was 6.2%. The participants were classified into low- (10%) risk groups. The percentage of participants that fell into these groups was 59.4%, 19.8% and 20.8% respectively. The proportion of participants in the high-risk group was similar to the 4-year incidence of hypertension (21.3%) in the Turkish population. Regression analysis showed that high salt consumption and low educational level significantly increased the risk of hypertension. Economic level, fat consumption, life satisfaction, physical activity, and fruit and vegetable consumption were not correlated with risk of hypertension. This study shows that FHRPS can also be used for predicting risk of hypertension in Central Anatolia. PMID:27432406

  4. Normative equations for central augmentation index: assessment of inter-population applicability and how it could be improved

    Science.gov (United States)

    Jeroncic, Ana; Gunjaca, Grgo; Mrsic, Danijela Budimir; Mudnic, Ivana; Brizic, Ivica; Polasek, Ozren; Boban, Mladen

    2016-01-01

    Common reference values of arterial stiffness indices could be effective screening tool in detecting vascular phenotypes at risk. However, populations of the same ethnicity may differ in vascular phenotype due to different environmental pressure. We examined applicability of normative equations for central augmentation index (cAIx) derived from Danish population with low cardiovascular risk on the corresponding Croatian population from the Mediterranean area. Disagreement between measured and predicted cAIx was assessed by Bland-Altman analysis. Both, cAIx-age distribution and normative equation fitted on Croatian data were highly comparable to Danish low-risk sample. Contrarily, Bland-Altman analysis of cAIx disagreement revealed a curvilinear deviation from the line of full agreement indicating that the equations were not equally applicable across age ranges. Stratification of individual data into age decades eliminated curvilinearity in all but the 30–39 (men) and 40–49 (women) decades. In other decades, linear disagreement independent of age persisted indicating that cAIx determinants other than age were not envisaged/compensated for by proposed equations. Therefore, established normative equations are equally applicable to both Nordic and Mediterranean populations but are of limited use. If designed for narrower age ranges, the equations’ sensitivity in detecting vascular phenotypes at risk and applicability to different populations could be improved. PMID:27230110

  5. 78 FR 2416 - Agency Information Collection Activities: Application To Establish a Centralized Examination Station

    Science.gov (United States)

    2013-01-11

    ... necessary for the proper performance of the functions of the agency, including whether the information shall... the applicant's facility; the fairness of fee structure; and knowledge of cargo handling operations and of CBP procedures. The names of all corporate officers and all employees who will come in...

  6. Cafeteria diet induces obesity and insulin resistance associated with oxidative stress but not with inflammation: improvement by dietary supplementation with a melon superoxide dismutase.

    Science.gov (United States)

    Carillon, Julie; Romain, Cindy; Bardy, Guillaume; Fouret, Gilles; Feillet-Coudray, Christine; Gaillet, Sylvie; Lacan, Dominique; Cristol, Jean-Paul; Rouanet, Jean-Max

    2013-12-01

    Oxidative stress is involved in obesity. However, dietary antioxidants could prevent oxidative stress-induced damage. We have previously shown the preventive effects of a melon superoxide dismutase (SODB) on oxidative stress. However, the mechanism of action of SODB is still unknown. Here, we evaluated the effects of a 1-month curative supplementation with SODB on the liver of obese hamsters. Golden Syrian hamsters received either a standard diet or a cafeteria diet composed of high-fat, high-sugar, and high-salt supermarket products, for 15 weeks. This diet resulted in insulin resistance and in increased oxidative stress in the liver. However, inflammatory markers (IL-6, TNF-α, and NF-κB) were not enhanced and no liver steatosis was detected, although these are usually described in obesity-induced insulin resistance models. After the 1-month supplementation with SODB, body weight and insulin resistance induced by the cafeteria diet were reduced and hepatic oxidative stress was corrected. This could be due to the increased expression of the liver antioxidant defense proteins (manganese and copper/zinc superoxide dismutase, catalase, and glutathione peroxidase). Even though no inflammation was detected in the obese hamsters, inflammatory markers were decreased after SODB supplementation, probably through the reduction of oxidative stress. These findings suggest for the first time that SODB could exert its antioxidant properties by inducing the endogenous antioxidant defense. The mechanisms underlying this induction need to be further investigated.

  7. Lack of tissue accumulation of grape seed flavanols after daily long-term administration in healthy and cafeteria-diet obese rats.

    Science.gov (United States)

    Margalef, Maria; Pons, Zara; Iglesias-Carres, Lisard; Bravo, Francisca Isabel; Muguerza, Begoña; Arola-Arnal, Anna

    2015-11-18

    After ingestion flavanols are metabolized by phase-II enzymes and the microbiota and are distributed throughout the body depending on several factors. Herein we aim to evaluate whether flavanols are tissue-accumulated after the long-term administration of a grape seed polyphenol extract (GSPE) in rats and to study if compounds present in tissues differ in a cafeteria-diet obesity state. For that, plasma, liver, mesenteric white adipose tissue (MWAT), brain, and aorta flavanol metabolites from standard chow-diet-fed (ST) and cafeteria-diet-fed (CAF) rats were analyzed by high-performance liquid chromatography electrospray ionization tandem mass spectrometry (HPLC-ESI-MS/MS) 21 h after the last 12-week-daily GSPE (100 mg/kg) dosage. Results showed that long-term GSPE intake did not trigger a flavanol tissue accumulation, indicating a clearance of products at each daily dosage. Therefore, results suggest that polyphenol benefits in a disease state would be due to a daily pulsatile effect. Moreover, obesity induced by diet also influences the metabolism and bioavailability of flavanols in rats. PMID:26496863

  8. Cafeteria diet induces obesity and insulin resistance associated with oxidative stress but not with inflammation: improvement by dietary supplementation with a melon superoxide dismutase.

    Science.gov (United States)

    Carillon, Julie; Romain, Cindy; Bardy, Guillaume; Fouret, Gilles; Feillet-Coudray, Christine; Gaillet, Sylvie; Lacan, Dominique; Cristol, Jean-Paul; Rouanet, Jean-Max

    2013-12-01

    Oxidative stress is involved in obesity. However, dietary antioxidants could prevent oxidative stress-induced damage. We have previously shown the preventive effects of a melon superoxide dismutase (SODB) on oxidative stress. However, the mechanism of action of SODB is still unknown. Here, we evaluated the effects of a 1-month curative supplementation with SODB on the liver of obese hamsters. Golden Syrian hamsters received either a standard diet or a cafeteria diet composed of high-fat, high-sugar, and high-salt supermarket products, for 15 weeks. This diet resulted in insulin resistance and in increased oxidative stress in the liver. However, inflammatory markers (IL-6, TNF-α, and NF-κB) were not enhanced and no liver steatosis was detected, although these are usually described in obesity-induced insulin resistance models. After the 1-month supplementation with SODB, body weight and insulin resistance induced by the cafeteria diet were reduced and hepatic oxidative stress was corrected. This could be due to the increased expression of the liver antioxidant defense proteins (manganese and copper/zinc superoxide dismutase, catalase, and glutathione peroxidase). Even though no inflammation was detected in the obese hamsters, inflammatory markers were decreased after SODB supplementation, probably through the reduction of oxidative stress. These findings suggest for the first time that SODB could exert its antioxidant properties by inducing the endogenous antioxidant defense. The mechanisms underlying this induction need to be further investigated. PMID:23792771

  9. Simple interventions to improve healthy eating behaviors in the school cafeteria.

    Science.gov (United States)

    Kessler, Holly S

    2016-03-01

    The National School Lunch Program in the United States provides an important opportunity to improve nutrition for the 30 million children who participate every school day. The purpose of this narrative review is to present and evaluate simple, evidence-based strategies to improve healthy eating behaviors at school. Healthy eating behaviors are defined as increased selection/consumption of fruits and/or vegetables, increased selection of nutrient-dense foods, or decreased selection of low-nutrient, energy-dense foods. Data were collected from sales records, 24-hour food recalls, direct observation, and estimation of plate waste. The review is limited to simple, discrete interventions that are easy to implement. Sixteen original, peer-reviewed articles are included. Interventions are divided into 5 categories: modification of choice, behavior modification, marketing strategies, time-efficiency strategies, and fruit slicing. All interventions resulted in improved eating behaviors, but not all interventions are applicable or feasible in all settings. Because these studies were performed prior to the implementation of the new federally mandated school meal standards, it is unknown if these interventions would yield similar results if repeated now.

  10. Simple interventions to improve healthy eating behaviors in the school cafeteria.

    Science.gov (United States)

    Kessler, Holly S

    2016-03-01

    The National School Lunch Program in the United States provides an important opportunity to improve nutrition for the 30 million children who participate every school day. The purpose of this narrative review is to present and evaluate simple, evidence-based strategies to improve healthy eating behaviors at school. Healthy eating behaviors are defined as increased selection/consumption of fruits and/or vegetables, increased selection of nutrient-dense foods, or decreased selection of low-nutrient, energy-dense foods. Data were collected from sales records, 24-hour food recalls, direct observation, and estimation of plate waste. The review is limited to simple, discrete interventions that are easy to implement. Sixteen original, peer-reviewed articles are included. Interventions are divided into 5 categories: modification of choice, behavior modification, marketing strategies, time-efficiency strategies, and fruit slicing. All interventions resulted in improved eating behaviors, but not all interventions are applicable or feasible in all settings. Because these studies were performed prior to the implementation of the new federally mandated school meal standards, it is unknown if these interventions would yield similar results if repeated now. PMID:26874753

  11. Treadmill Intervention Attenuates the Cafeteria Diet-Induced Impairment of Stress-Coping Strategies in Young Adult Female Rats

    Science.gov (United States)

    Cigarroa, Igor; Lalanza, Jaume F.; Caimari, Antoni; del Bas, Josep M.; Capdevila, Lluís; Arola, Lluís; Escorihuela, Rosa M.

    2016-01-01

    The current prevalence of diet-induced overweight and obesity in adolescents and adults is continuously growing. Although the detrimental biochemical and metabolic consequences of obesity are widely studied, its impact on stress-coping behavior and its interaction with specific exercise doses (in terms of intensity, duration and frequency) need further investigation. To this aim, we fed adolescent rats either an obesogenic diet (cafeteria diet, CAF) or standard chow (ST). Each group was subdivided into four subgroups according to the type of treadmill intervention as follows: a sedentary group receiving no manipulation; a control group exposed to a stationary treadmill; a low-intensity treadmill group trained at 12 m/min; and a higher intensity treadmill group trained at 17 m/min. Both the diet and treadmill interventions started at weaning and lasted for 8 weeks. Subjects were tested for anxiety-like behavior in the open field test and for coping strategies in the two-way active avoidance paradigm at week 7 and were sacrificed at week 8 for biometric and metabolic characterization. CAF feeding increased the weight gain, relative retroperitoneal white adipose tissue (RWAT %), and plasma levels of glucose, insulin, triglycerides and leptin and decreased the insulin sensitivity. Treadmill intervention partially reversed the RWAT% and triglyceride alterations; at higher intensity, it decreased the leptin levels of CAF-fed animals. CAF feeding decreased the motor activity and impaired the performance in a two-way active avoidance assessment. Treadmill intervention reduced defecation in the shuttle box, suggesting diminished anxiety. CAF feeding combined with treadmill training at 17 m/min increased the time spent in the center of the open field and more importantly, partially reversed the two-way active avoidance deficit. In conclusion, this study demonstrates that at doses that decreased anxiety-like behavior, treadmill exercise partially improved the coping strategy

  12. Application of the central composite design to optimize the preparation of novel micelles of harmine

    Directory of Open Access Journals (Sweden)

    Bei YY

    2013-05-01

    Full Text Available Yong-Yan Bei,1,* Xiao-Feng Zhou,2,3,* Ben-Gang You,1 Zhi-Qiang Yuan,1 Wei-Liang Chen,1 Peng Xia,1 Yang Liu,1 Yong Jin,4 Xiao-Juan Hu,1 Qiao-Ling Zhu,1 Chun-Ge Zhang,1 Xue-Nong Zhang,1 Liang Zhang5 1Department of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, People’s Republic of China; 2College of Radiological Medicine and Protection, Soochow University, Suzhou, People’s Republic of China; 3Changshu Hospital of Traditional Chinese Medicine, Changshu, People’s Republic of China; 4Invasive Technology Department, The Second Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 5Department of Biopharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou, People’s Republic of China*These authors contributed equally to the paperAbstract: Lactose–palmitoyl–trimethyl–chitosan (Lac-TPCS, a novel amphipathic self-assembled polymer, was synthesized for administration of insoluble drugs to reduce their adverse effects. The central composite design was used to study the preparation technique of harmine (HM-loaded self-assembled micelles based on Lac-TPCS (Lac-TPCS/HM. Three preparation methods and single factors were screened, including solvent type, HM amount, hydration volume, and temperature. The optimal preparation technique was identified after investigating the influence of two independent factors, namely, HM amount and hydration volume, on four indexes, ie, encapsulation efficiency (EE, drug-loading amount (LD, particle size, and polydispersity index (PDI. Analysis of variance showed a high coefficient of determination of 0.916 to 0.994, thus ensuring a satisfactory adjustment of the predicted prescription. The maximum predicted values of the optimal prescription were 91.62%, 14.20%, 183.3 nm, and 0.214 for EE, LD, size, and PDI, respectively, when HM amount was 1.8 mg and hydration volume was 9.6 mL. HM-loaded micelles were successfully characterized by

  13. TuBaFrost 5: multifunctional central database application for a European tumor bank.

    Science.gov (United States)

    Isabelle, M; Teodorovic, I; Morente, M M; Jaminé, D; Passioukov, A; Lejeune, S; Therasse, P; Dinjens, W N M; Oosterhuis, J W; Lam, K H; Oomen, M H A; Spatz, A; Ratcliffe, C; Knox, K; Mager, R; Kerr, D; Pezzella, F; van de Vijver, M; van Boven, H; Alonso, S; Kerjaschki, D; Pammer, J; Lopez-Guerrero, J A; Llombart Bosch, A; Carbone, A; Gloghini, A; van Veen, E-B; van Damme, B; Riegman, P H J

    2006-12-01

    Developing a tissue bank database has become more than just logically arranging data in tables combined with a search engine. Current demand for high quality samples and data, and the ever-changing legal and ethical regulations mean that the application must reflect TuBaFrost rules and protocols for the collection, exchange and use of tissue. To ensure continuation and extension of the TuBaFrost European tissue bank, the custodianship of the samples, and hence the decision over whether to issue samples to requestors, remains with the local collecting centre. The database application described in this article has been developed to facilitate this open structure virtual tissue bank model serving a large group. It encompasses many key tasks, without the requirement for personnel, hence minimising operational costs. The Internet-accessible database application enables search, selection and request submission for requestors, whereas collectors can upload and edit their collection. Communication between requestor and involved collectors is started with automatically generated e-mails. PMID:17029787

  14. Application of scientific core drilling to geothermal exploration: Platanares, Honduras and Tecuamburro Volcano, Guatemala, Central America

    Energy Technology Data Exchange (ETDEWEB)

    Goff, S.J.; Goff, F.E.; Heiken, G.H. [Los Alamos National Lab., NM (United States); Duffield, W.A. [Geological Survey, Flagstaff, AZ (United States); Janik, C.J. [Geological Survey, Menlo Park, CA (United States)

    1994-04-01

    Our efforts in Honduras and Guatemala were part of the Central America Energy Resource Project (CAERP) funded by the United States Agency for International Development (AID). Exploration core drilling operations at the Platanares, Honduras and Tecuamburro Volcano, Guatemala sites were part of a geothermal assessment for the national utility companies of these countries to locate and evaluate their geothermal resources for electrical power generation. In Honduras, country-wide assessment of all thermal areas determined that Platanares was the site with the greatest geothermal potential. In late 1986 to middle 1987, three slim core holes were drilled at Platanares to a maximum depth of 680 m and a maximum temperature of 165{degree}C. The objectives were to obtain information on the geothermal gradient, hydrothermal alterations, fracturing, and possible inflows of hydrothermal fluids. Two holes produced copious amounts of water under artesian conditions and a total of 8 MW(t) of energy. Geothermal investigations in Guatemala focused on the Tecuamburro Volcano geothermal site. The results of surface geological, volcanological, hydrogeochemical, and geophysical studies at Tecuamburro Volcano indicated a substantial shallow heat source. In early 1990 we drilled one core hole, TCB-1, to 808 m depth. The measured bottom hole temperature was 238{degree}C. Although the borehole did not flow, in-situ samples indicate the hole is completed in a vapor-zone above a probable 300{degree}C geothermal reservoir.

  15. Improving semi-automated glacier mapping with a multi-method approach: applications in central Asia

    Science.gov (United States)

    Smith, T.; Bookhagen, B.; Cannon, F.

    2015-09-01

    Studies of glaciers generally require precise glacier outlines. Where these are not available, extensive manual digitization in a geographic information system (GIS) must be performed, as current algorithms struggle to delineate glacier areas with debris cover or other irregular spectral profiles. Although several approaches have improved upon spectral band ratio delineation of glacier areas, none have entered wide use due to complexity or computational intensity. In this study, we present and apply a glacier mapping algorithm in Central Asia which delineates both clean glacier ice and debris-covered glacier tongues. The algorithm is built around the unique velocity and topographic characteristics of glaciers and further leverages spectral and spatial relationship data. We found that the algorithm misclassifies between 2 and 10 % of glacier areas, as compared to a ~ 750 glacier control data set, and can reliably classify a given Landsat scene in 3-5 min. The algorithm does not completely solve the difficulties inherent in classifying glacier areas from remotely sensed imagery but does represent a significant improvement over purely spectral-based classification schemes, such as the band ratio of Landsat 7 bands three and five or the normalized difference snow index. The main caveats of the algorithm are (1) classification errors at an individual glacier level, (2) reliance on manual intervention to separate connected glacier areas, and (3) dependence on fidelity of the input Landsat data.

  16. Application of synchrotron radiation for elemental microanalysis of human central nervous System tissue

    Science.gov (United States)

    Szczerbowska-Boruchowska, M.; Lankosz, M.; Ostachowicz, J.; Adamek, D.; Krygowska-Wajs, A.; Tomik, B.; Szczudlik, A.; Simionovici, A.; Bohic, S.

    2003-03-01

    The pathogenesis of two neurodegenerative diseases i.e. Parkinson's Disease (PD) and amyotrophic lateral sclerosis (ALS) are still not known. It is supposed that disturbance of metal ions homeostasis may promote degeneration and atrophy of neurones. As a preliminary study. the quantitative and topographic elemental analysis of selected parts of human brain and spinal cord was performed using synchrotron microbeam-X ray fluorescence (μ-SXRF) technique. The samples were taken during the autopsy from patients with PD, ALS and from patients died due to non-neurological conditions events. X-ray fluorescence imaging showed that increased concentration of selected elements are observed in neurons perikarial parts in compare with surrounding area. Moreover, comparable analysis showed significant differences in accumulation of selected elements between the pathological and control cases. The investigations indicate that micro-beam of synchrotron radiation can be satisfactory applied for analysis of central nervous System tissue providing useful information about distribution and contents of elements at the single cell level.

  17. Application of Paleoseismology to Seismic Hazard Analysis in the Central and Eastern United States (CEUS)

    International Nuclear Information System (INIS)

    Paleoseismology techniques have been applied across the CEUS (Central and Eastern United States) to augment seismic data and to improve seismic hazard analyses. Considering paleoseismic data along with historic data may increase the number of events and their maximum magnitudes (Mmax), which may decrease the recurrence time of seismic events included in hazard calculations. More importantly, paleoseismic studies extend the length of the earthquake record often by 1000s–10,000s of years and reduce uncertainties related to sources, magnitude, and recurrence times of earthquakes. The CEUS Seismic Source Characterization (Technical Report, [108]) uses a lot of paleoseismic data in building the source model for seismic hazard analyses. Most of these data are derived through study of paleoliquefaction features. Appendix E of the Technical Report compiles data from ten distinct regions in eastern North America where paleoliquefaction features have been used to improve knowledge of regional seismic history. These regions are shown. Paleoliquefaction data can significantly impact seismic hazard calculations by better defining earthquake sources, Mmax for those sources, and recurrence rates of large earthquakes

  18. Effect of road salt application on seasonal chloride concentrations and toxicity in south-central Indiana streams.

    Science.gov (United States)

    Gardner, Kristin M; Royer, Todd V

    2010-01-01

    Contemporary information on road salt runoff is needed for management of water resources in regions experiencing urbanization and increased road density. We investigated seasonal Cl(-) concentrations among five streams in south-central Indiana that drained watersheds varying in degree of urbanization and ranging in size from 9.3 to 27 km(2). We also conducted acute toxicity tests with Daphnia pulex to assess the potential effects of the observed Cl(-) concentrations on aquatic life. Periods of elevated Cl(-) concentrations were observed during the winters of 2007-08 and 2008-09 at all sites except the reference site. The highest Cl(-) concentration observed during the study was 2100 mg L(-1) and occurred at the most urbanized site. The Cl(-) concentration at the reference site never exceeded 22 mg L(-1). The application of road salt caused large increases in stream Cl(-) concentrations, but the elevated Cl(-) levels did not appear to be a significant threat to aquatic life based on our toxicity testing. Only the most urbanized site showed evidence of salt retention within the watershed, whereas the other sites exported the road salt relatively quickly after its application, suggesting storm drains and impervious surfaces minimized interaction between soils and salt-laden runoff. During winter at these sites, the response in stream Cl(-) concentrations appeared to be controlled by the timing and intensity of road salt application, the magnitude of precipitation, and the occurrence of air temperatures that caused snowmelt and generated runoff.

  19. Politics of form. Genealogy of a central thesis of modernity and history of its application

    OpenAIRE

    Schober, Anna

    2002-01-01

    The present project comprises two specific goals the first is to write a genealogy of the claim that the aesthetic trick of montage, alienation and parody has a political effect and to complete a history of the application of this "thesis" in the 20th century, with three social groups being selected for a detailed analysis: the Dadaist film and exhibition practices of the 1910s and 1920s; the Expanded-Cinema Movement of the 60s and 70s in Vienna; art collectives such as FIA, SKART, OTPOR, Led...

  20. Central Nervous System Disease in Hematological Malignancies: Historical Perspective and Practical Applications

    Science.gov (United States)

    Pui, Ching-Hon; Thiel, Eckhard

    2009-01-01

    Acute lymphoblastic leukemia (ALL) 5-year survival rates are approaching 90% in children and 50% in adults who are receiving contemporary risk-directed treatment protocols. Current efforts focus not only on further improving cure rate but also on patient quality of life. Hence, all protocols decrease or limit the use of cranial irradiation as central nervous system (CNS)-directed therapy, even in patients with high-risk presenting features, such as the presence of leukemia cells in the cerebrospinal fluid (even resulting from traumatic lumbar puncture), adverse genetic features, T-cell immunophenotype, and a large leukemia-cell burden. Current strategies for CNS-directed therapy involve effective systemic chemotherapy (eg, dexamethasone, high-dose methotrexate, intensive asparaginase, ifosfamide) and early intensification and optimization of intrathecal therapy. Options under investigation for the treatment of relapsed or refractory CNS leukemia in ALL patients include thiotepa and intrathecal liposomal cytarabine. CNS involvement in non-Hodgkin’s lymphoma (NHL) is associated with young age, advanced stage, number of extranodal sites, elevated lactate dehydrogenase, and International Prognostic Index score. Refractory CNS lymphoma in patients with NHL carries a poor prognosis, with a median survival of 2 to 6 months; the most promising treatment, autologous stem cell transplant, can extend median survival from 10 to 26 months. CNS prophylaxis is required during the initial treatment of NHL subtypes that carry a high risk of CNS relapse, such as B-cell ALL, Burkitt’s lymphoma, and lymphoblastic lymphoma. The use of CNS prophylaxis in the treatment of diffuse large B-cell lymphoma is controversial because of the low risk of CNS relapse (~5%) in this population. In this article, we review current and past practice of intrathecal therapy in ALL and NHL and the risk-models that aim to identify predictors of CNS relapse in NHL. PMID:19660680

  1. Application of solar energy in heating and cooling of residential buildings under Central Asian conditions

    Directory of Open Access Journals (Sweden)

    Usmonov Shukhrat Zaurovich

    2014-04-01

    Full Text Available Solar radiation is the main source of thermal energy for almost all the processes developing in the atmosphere, hydrosphere, and biosphere. The total duration of sunshine in Tajikistan ranges from 2100 to 3170 hours per year. Solar collectors can be mounted on the roof of a house after its renovation and modernization. One square meter of surface area in Central Asia accounts for up to 1600 kW/h of solar energy gain, whilst the average gain is 1200 kW/h. Active solar thermal systems are able to collect both low- and high-temperature heat. Active systems require the use of special engineering equipment for the collection, storage, conversion and distribution of heat, while a low-grade system is based on the principle of using a flat solar collector. The collector is connected to the storage tank for storing the heated water, gas, etc. The water temperature is in the range 50-60 °C. For summer air conditioning in hot climates, absorption-based solar installations with open evaporating solution are recommended. The UltraSolar PRO system offers an opportunity to make a home independent of traditional electricity. Combining Schneider Electric power generation and innovative energy storage technology results in an independent power supply. Traditional power supply systems can be short-lived since they store energy in lead-acid batteries which have a negligible lifetime. Lead-acid batteries operate in a constant charge-discharge mode, require specific conditions for best performance and can fail suddenly. Sudden failure of lead acid batteries, especially in winter in the northern part of Tajikistan, completely disables the heating system of a building. Instead, it is recommended to use industrial lithium-ion batteries, which have a significantly longer life and reliability compared to lead-acid type. UltraSolar PRO are ideal and provide a complete package, low noise and compact lithium-ion power supply.

  2. Applications of a GIS on Georisks for Nicaragua and Central America

    Science.gov (United States)

    Strauch, W.; Chavez, G.; Gutierrez, V.; Feldhaus, L.; Schillinger, S.; Schmidt, R.

    2007-05-01

    A GIS on Georisks in Nicaragua was developed in the last years at the Instituto Nicaraguense de Estudios Territoriales (INETER) in cooperation with Federal Institute for Geosciences and Natural Resources (BGR, Germany). This GIS includes extensive topographical coverage and a large part of the data obtained in Nicaragua in many recent projects on natural hazard, vulnerability and risk. It contains numerous data on elements under risk, for instance cadastre data of Nicaraguan cities. Activities include the integration of the GIS with the monitoring and early warning systems of INETER to update certain parts of the data base continuously and in real time. The GIS is used on a routine basis at INETER and the GIS data base provides an efficient starting point for multiple new projects on georisks in Nicaragua which after their termination deliver their products to the GIS to assure the continuous growth of the system. Local universities, governmental institutions, local administrations, NGO´s make use of the GIS data base. Examples of important datasets are the seismicity data of Nicaragua with around 30,000 events, landslide coverage with 17,000 events, seismic vulnerability of 212,000 buildings in Managua city, seismic microzonation data of several towns, and multidisciplinary hazard and vulnerability data for 30 municipalities in Western Nicaragua. An interdisciplinary group of Nicaraguan geoscientists, informatics engineers and GIS specialists at INETER was trained to develop and use the GIS in their daily work. Web mapping services were put onto INETER´s website to provide the general public in Nicaragua with direct access to the data. Based on the experience in Nicaragua a regional GIS on Georisks for Central America is under development in cooperation with other institutions in El Salvador, Guatemala and Honduras.

  3. A Holistic Approach to Healthy School Meals: "How Hopkins High School Looked Beyond its Cafeteria when it Changed Meal Service from Fast Food to Nutritional Food. IssueTrak": A CEFPI Brief on Educational Facility Issues

    Science.gov (United States)

    Dufault, Timothy; Parsons, Meg

    2006-01-01

    The new cafeteria at Hopkins High School in Minnetonka, Minnesota is part restaurant, part study hall, part lounge area and part health-food store. From the beginning, the superintendent and food service leaders planned the facility to ensure that balanced diets with quickly prepared, but healthy, foods are offered to students to help them…

  4. Lentivirus-mediated gene transfer to the central nervous system: therapeutic and research applications.

    Science.gov (United States)

    Wong, Liang-Fong; Goodhead, Lucy; Prat, Christine; Mitrophanous, Kyriacos A; Kingsman, Susan M; Mazarakis, Nicholas D

    2006-01-01

    The management of disorders of the nervous system remains a medical challenge. The key goals are to understand disease mechanisms, to validate therapeutic targets, and to develop new therapeutic strategies. Viral vector-mediated gene transfer can meet these goals and vectors based on lentiviruses have particularly useful features. Lentiviral vectors can deliver 8 kb of sequence, they mediate gene transfer into any neuronal cell type, expression and therapy are sustained, and normal cellular functions in vitro and in vivo are not compromised. After delivery into the nervous system they induce no significant immune responses, there are no unwanted side effects of the vectors per se to date, and manufacturing and safety testing for clinical applications are well advanced. There are now numerous examples of effective long-term treatment of animal models of neurological disorders, such as Parkinson's disease, Alzheimer's disease, Huntington's disease, motor neuron diseases, lysosomal storage diseases, and spinal injury, using a range of therapeutic genes expressed in lentiviral vectors. Significant issues remain in some areas of neural gene therapy including defining the optimum therapeutic gene(s), increasing the specificity of delivery, regulating expression of potentially toxic genes, and designing clinically relevant strategies. We discuss the applications of lentiviral vectors in therapy and research and highlight the essential features that will ensure their translation to the clinic in the near future. PMID:16409120

  5. Phytol a Natural Diterpenoid with Pharmacological Applications on Central Nervous System: A Review.

    Science.gov (United States)

    Pereira Costa, Jessica; da Silva Oliveira, Johanssy; Mario Rezende Junior, Luis; de Freitas, Rivelilson Mendes

    2014-01-01

    Phytol (3,7,11,15-tetramethylhexadec-2-en-1-ol), a diterpene member of long and ramified chain of unsaturated acyclic alcohols. The objective of study was to conduct a systematic review of this diterpene and its pharmaceutical applications in Nervous System diseases in humans and/or rodents. Periodicals bases, such as ScienceDirect and PubMed, were used, as well as technological basis of European Patent Office, World Intellectual Property Organization, United States Patent and Trademark Office, Derwent Innovations Index(®), Latin American Bank of Patents and data base of Instituto Nacional de Propriedade Industrial (INPI-National Institute of Industrial Property). The software EndNote-X5 was utilized as reference with the keywords: phytol, anxiolytic, antidepressant and anticonvulsant and their correlations in English, Spanish and Portuguese from January 2003 to June 2014. There are many publications on phytol in international literature. However, there is a reduced number of articles related to pharmacological activities proposed here. In reference to technological bases, patents present a wide range of pharmacological and commercial applications as cosmetics, hypolipodemic, anxiolytic and antidepressant. Therefore, it is necessary to explore phytol molecules, which present high pharmacological potential from scientific and technological points of view, in search of transference of technologies to generate economical and industrial growth. PMID:27099143

  6. Phytol a Natural Diterpenoid with Pharmacological Applications on Central Nervous System: A Review.

    Science.gov (United States)

    Pereira Costa, Jessica; da Silva Oliveira, Johanssy; Mario Rezende Junior, Luis; de Freitas, Rivelilson Mendes

    2014-01-01

    Phytol (3,7,11,15-tetramethylhexadec-2-en-1-ol), a diterpene member of long and ramified chain of unsaturated acyclic alcohols. The objective of study was to conduct a systematic review of this diterpene and its pharmaceutical applications in Nervous System diseases in humans and/or rodents. Periodicals bases, such as ScienceDirect and PubMed, were used, as well as technological basis of European Patent Office, World Intellectual Property Organization, United States Patent and Trademark Office, Derwent Innovations Index(®), Latin American Bank of Patents and data base of Instituto Nacional de Propriedade Industrial (INPI-National Institute of Industrial Property). The software EndNote-X5 was utilized as reference with the keywords: phytol, anxiolytic, antidepressant and anticonvulsant and their correlations in English, Spanish and Portuguese from January 2003 to June 2014. There are many publications on phytol in international literature. However, there is a reduced number of articles related to pharmacological activities proposed here. In reference to technological bases, patents present a wide range of pharmacological and commercial applications as cosmetics, hypolipodemic, anxiolytic and antidepressant. Therefore, it is necessary to explore phytol molecules, which present high pharmacological potential from scientific and technological points of view, in search of transference of technologies to generate economical and industrial growth.

  7. Electrochemical techniques application in corrosion problems of fossil power plants; Aplicacion de tecnicas electroquimicas en problemas de corrosion en centrales termoelectricas

    Energy Technology Data Exchange (ETDEWEB)

    Cano Castillo, Ulises; Garcia Ochoa, Esteban Miguel; Martinez Villafane, Alberto; Mariaca Rodriguez, Liboria; Malo Tamayo, Jose Maria; Uruchurtu Chavarin, Jorge [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1990-12-31

    Some aspects of the electrochemical techniques employed to evaluate the corrosion at low temperature in fossil power plants are commented, as well as the results obtained with the application of them in three power plants of this type. [Espanol] Se comentan algunos aspectos de tecnicas electroquimicas utilizadas para evaluar la corrosion en baja temperatura en centrales termoelectricas, asi como los resultados de la aplicacion de las mismas en tres centrales de este tipo.

  8. Duke Surgery Research Central: an open-source Web application for the improvement of compliance with research regulation

    Directory of Open Access Journals (Sweden)

    Martins Henrique

    2006-07-01

    Full Text Available Abstract Background Although regulatory compliance in academic research is enforced by law to ensure high quality and safety to participants, its implementation is frequently hindered by cost and logistical barriers. In order to decrease these barriers, we have developed a Web-based application, Duke Surgery Research Central (DSRC, to monitor and streamline the regulatory research process. Results The main objective of DSRC is to streamline regulatory research processes. The application was built using a combination of paper prototyping for system requirements and Java as the primary language for the application, in conjunction with the Model-View-Controller design model. The researcher interface was designed for simplicity so that it could be used by individuals with different computer literacy levels. Analogously, the administrator interface was designed with functionality as its primary goal. DSRC facilitates the exchange of regulatory documents between researchers and research administrators, allowing for tasks to be tracked and documents to be stored in a Web environment accessible from an Intranet. Usability was evaluated using formal usability tests and field observations. Formal usability results demonstrated that DSRC presented good speed, was easy to learn and use, had a functionality that was easily understandable, and a navigation that was intuitive. Additional features implemented upon request by initial users included: extensive variable categorization (in contrast with data capture using free text, searching capabilities to improve how research administrators could search an extensive number of researcher names, warning messages before critical tasks were performed (such as deleting a task, and confirmatory e-mails for critical tasks (such as completing a regulatory task. Conclusion The current version of DSRC was shown to have excellent overall usability properties in handling research regulatory issues. It is hoped that its

  9. The cafeteria terrace

    CERN Multimedia

    1987-01-01

    The large terrace area outside Restaurant 1 at CERN is a hive of activity in the summer. Visitors and staff members meet here for breaks from work. Often the air is filled with discussion in many different accents and languages on topics from theoretical physics to the weekend's activities.

  10. Nonradioactive Air Emissions Notice of Construction (NOC) Application for the Central Waste Complex (CSC) for Storage of Vented Waste Containers

    Energy Technology Data Exchange (ETDEWEB)

    KAMBERG, L.D.

    2000-04-01

    This Notice of Construction (NOC) application is submitted for the storage and management of waste containers at the Central Waste Complex (CWC) stationary source. The CWC stationary source consists of multiple sources of diffuse and fugitive emissions, as described herein. This NOC is submitted in accordance with the requirements of Washington Administrative Code (WAC) 173-400-110 (criteria pollutants) and 173-460-040 (toxic air pollutants), and pursuant to guidance provided by the Washington State Department of Ecology (Ecology). Transuranic (TRU) mixed waste containers at CWC are vented to preclude the build up of hydrogen produced as a result of radionuclide decay, not as safety pressure releases. The following activities are conducted within the CWC stationary source: Storage and inspection; Transfer and staging; Packaging; Treatment; and Sampling. This NOC application is intended to cover all existing storage structures within the current CWC treatment, storage, and/or disposal (TSD) boundary, as well as any storage structures, including waste storage pads and staging areas, that might be constructed in the future within the existing CWC boundary.

  11. Nonradioactive Air Emissions Notice of Construction (NOC) Application for the Central Waste Complex (CSC) for Storage of Vented Waste Containers

    International Nuclear Information System (INIS)

    This Notice of Construction (NOC) application is submitted for the storage and management of waste containers at the Central Waste Complex (CWC) stationary source. The CWC stationary source consists of multiple sources of diffuse and fugitive emissions, as described herein. This NOC is submitted in accordance with the requirements of Washington Administrative Code (WAC) 173-400-110 (criteria pollutants) and 173-460-040 (toxic air pollutants), and pursuant to guidance provided by the Washington State Department of Ecology (Ecology). Transuranic (TRU) mixed waste containers at CWC are vented to preclude the build up of hydrogen produced as a result of radionuclide decay, not as safety pressure releases. The following activities are conducted within the CWC stationary source: Storage and inspection; Transfer and staging; Packaging; Treatment; and Sampling. This NOC application is intended to cover all existing storage structures within the current CWC treatment, storage, and/or disposal (TSD) boundary, as well as any storage structures, including waste storage pads and staging areas, that might be constructed in the future within the existing CWC boundary

  12. Efficient GIS-based model-driven method for flood risk management and its application in central China

    Science.gov (United States)

    Liu, Y.; Zhou, J.; Song, L.; Zou, Q.; Guo, J.; Wang, Y.

    2014-02-01

    In recent years, an important development in flood management has been the focal shift from flood protection towards flood risk management. This change greatly promoted the progress of flood control research in a multidisciplinary way. Moreover, given the growing complexity and uncertainty in many decision situations of flood risk management, traditional methods, e.g., tight-coupling integration of one or more quantitative models, are not enough to provide decision support for managers. Within this context, this paper presents a beneficial methodological framework to enhance the effectiveness of decision support systems, through the dynamic adaptation of support regarding the needs of the decision-maker. In addition, we illustrate a loose-coupling technical prototype for integrating heterogeneous elements, such as multi-source data, multidisciplinary models, GIS tools and existing systems. The main innovation is the application of model-driven concepts, which put the system in a state of continuous iterative optimization. We define the new system as a model-driven decision support system (MDSS ). Two characteristics that differentiate the MDSS are as follows: (1) it is made accessible to non-technical specialists; and (2) it has a higher level of adaptability and compatibility. Furthermore, the MDSS was employed to manage the flood risk in the Jingjiang flood diversion area, located in central China near the Yangtze River. Compared with traditional solutions, we believe that this model-driven method is efficient, adaptable and flexible, and thus has bright prospects of application for comprehensive flood risk management.

  13. 集中管理模式在消毒供应中心的应用%The Application of Centralized Model in Central Sterile Supply Department

    Institute of Scientific and Technical Information of China (English)

    黄金芳; 黎婷; 何华聪

    2013-01-01

    目的:探讨再生器械的清洗质量。方法:选取供应室实施集中管理模式前后的清洗消毒器械600件分别取样监测,比较清洗效果。结果:供应室实施集中管理模式后(实验组)再生器械的清洗合格率明显高于集中管理模式实施之前(对照组),两者比较差异有统计学意义(p<0.01)。结论:再生医疗器械集中管理模式能有效提高再生医疗器械清洗质量、消毒灭菌效果。%Objective To investigate the cleaning quality of regenerated medical instrument. Methods 6oo sterilized instruments were monitored before and after the implementation of centralized model respectively to compare the cleaning effects. Results The qualified rate of the washing after the implementation of centralized model (the experimental group) was higher than that before (the control group). The difference between two groups was statisticstical y significant (P<0.01) . Conclusions The centralized model of regenerated medical instruments can effectively improve the cleaning quality and the sterilization effect.

  14. Recognition of central sensitization in patients with musculoskeletal pain: Application of pain neurophysiology in manual therapy practice.

    NARCIS (Netherlands)

    Nijs, J.; Houdenhove, B. Van; Oostendorp, R.A.B.

    2010-01-01

    Central sensitization plays an important role in the pathophysiology of numerous musculoskeletal pain disorders, yet it remains unclear how manual therapists can recognize this condition. Therefore, mechanism based clinical guidelines for the recognition of central sensitization in patients with mus

  15. Inflamação renal, alterações metabólicas e oxidativas após 6 semanas de dieta de cafeteria em ratos

    OpenAIRE

    Maria Eugênia Lopes Navarro; Klinsmann Carolo dos Santos; André Ferreira do Nascimento; Fabiane Valentini Francisqueti; Igor Otávio Minatel; Damiana Tortolero Pierine; Renata de Azevedo Melo Luvizotto; Ana Lúcia A. Ferreira; Dijon Henrique Salomé de Campos; Camila Renata Corrêa

    2016-01-01

    Resumo Introdução: A obesidade é uma doença em que a inflamação está inteiramente envolvida e pode causar insuficiência renal. Objetivo: Avaliar a influência da exposição a curto prazo de uma dieta de cafeteria sobre a inflamação no tecido renal e a formação de produtos de glicação avançada (AGEs) no plasma de rato. Métodos: Ratos Wistar machos (10 semanas de idade, pesando 350 g) foram designados para receber dieta de ração comercial (C; n = 8 animais/grupo, 5% de energia a partir de gord...

  16. Towards an automatic statistical model for seasonal precipitation prediction and its application to Central and South Asian headwater catchments

    Science.gov (United States)

    Gerlitz, Lars; Gafurov, Abror; Apel, Heiko; Unger-Sayesteh, Katy; Vorogushyn, Sergiy; Merz, Bruno

    2016-04-01

    Statistical climate forecast applications typically utilize a small set of large scale SST or climate indices, such as ENSO, PDO or AMO as predictor variables. If the predictive skill of these large scale modes is insufficient, specific predictor variables such as customized SST patterns are frequently included. Hence statistically based climate forecast models are either based on a fixed number of climate indices (and thus might not consider important predictor variables) or are highly site specific and barely transferable to other regions. With the aim of developing an operational seasonal forecast model, which is easily transferable to any region in the world, we present a generic data mining approach which automatically selects potential predictors from gridded SST observations and reanalysis derived large scale atmospheric circulation patterns and generates robust statistical relationships with posterior precipitation anomalies for user selected target regions. Potential predictor variables are derived by means of a cellwise correlation analysis of precipitation anomalies with gridded global climate variables under consideration of varying lead times. Significantly correlated grid cells are subsequently aggregated to predictor regions by means of a variability based cluster analysis. Finally for every month and lead time, an individual random forest based forecast model is automatically calibrated and evaluated by means of the preliminary generated predictor variables. The model is exemplarily applied and evaluated for selected headwater catchments in Central and South Asia. Particularly the for winter and spring precipitation (which is associated with westerly disturbances in the entire target domain) the model shows solid results with correlation coefficients up to 0.7, although the variability of precipitation rates is highly underestimated. Likewise for the monsoonal precipitation amounts in the South Asian target areas a certain skill of the model could

  17. Hanford facility dangerous waste Part A, Form 3 and Part B permit application documentation, Central Waste Complex (WA7890008967)(TSD: TS-2-4)

    Energy Technology Data Exchange (ETDEWEB)

    Saueressig, D.G.

    1998-05-20

    The Hanford Facility Dangerous Waste Permit Application is considered to be a single application organized into a General Information Portion (document number DOE/RL-91-28) and a Unit-Specific Portion. The scope of the Unit-Specific Portion is limited to Part B permit application documentation submitted for individual, operating, treatment, storage, and/or disposal units, such as the Central Waste Complex (this document, DOE/RL-91-17). Both the General Information and Unit-Specific portions of the Hanford Facility Dangerous Waste Permit Application address the content of the Part B permit application guidance prepared by the Washington State Department of Ecology (Ecology 1996) and the U.S. Environmental Protection Agency (40 Code of Federal Regulations 270), with additional information needed by the Hazardous and Solid Waste Amendments and revisions of Washington Administrative Code 173-303. For ease of reference, the Washington State Department of Ecology alpha-numeric section identifiers from the permit application guidance documentation (Ecology 1996) follow, in brackets, the chapter headings and subheadings. A checklist indicating where information is contained in the Central Waste Complex permit application documentation, in relation to the Washington State Department of Ecology guidance, is located in the Contents section. Documentation contained in the General Information Portion is broader in nature and could be used by multiple treatment, storage, and/or disposal units (e.g., the glossary provided in the General Information Portion). Wherever appropriate, the Central Waste Complex permit application documentation makes cross-reference to the General Information Portion, rather than duplicating text. Information provided in this Central Waste Complex permit application documentation is current as of May 1998.

  18. Hanford facility dangerous waste Part A, Form 3, and Part B permit application documentation for the Central Waste Complex (WA7890008967) (TSD: TS-2-4)

    International Nuclear Information System (INIS)

    The Hanford Facility Dangerous Waste Permit Application is considered to be a single application organized into a General Information Portion (document number DOE/RL-91-28) and a Unit-Specific Portion. The scope of the Unit-Specific Portion is limited to Part B permit application documentation submitted for individual, operating, treatment, storage, and/or disposal units, such as the Central Waste Complex (this document, DOE/RL-91-17). Both the General Information and Unit-Specific portions of the Hanford Facility Dangerous Waste Permit Application address the content of the Part B permit application guidance prepared by the Washington State Department of Ecology (Ecology 1996) and the U.S. Environmental Protection Agency (40 Code of Federal Regulations 270), with additional information needed by the Hazardous and Solid Waste Amendments and revisions of Washington Administrative Code 173-303. For ease of reference, the Washington State Department of Ecology alpha-numeric section identifiers from the permit application guidance documentation (Ecology 1996) follow, in brackets, the chapter headings and subheadings. A checklist indicating where information is contained in the Central Waste Complex permit application documentation, in relation to the Washington State Department of Ecology guidance, is located in the Contents section. Documentation contained in the General Information Portion is broader in nature and could be used by multiple treatment, storage, and/or disposal units (e.g., the glossary provided in the General Information Portion). Wherever appropriate, the Central Waste Complex permit application documentation makes cross-reference to the General Information Portion, rather than duplicating text. Information provided in this Central Waste Complex permit application documentation is current as of May 1998

  19. Inflamação renal, alterações metabólicas e oxidativas após 6 semanas de dieta de cafeteria em ratos

    Directory of Open Access Journals (Sweden)

    Maria Eugênia Lopes Navarro

    2016-03-01

    Full Text Available Resumo Introdução: A obesidade é uma doença em que a inflamação está inteiramente envolvida e pode causar insuficiência renal. Objetivo: Avaliar a influência da exposição a curto prazo de uma dieta de cafeteria sobre a inflamação no tecido renal e a formação de produtos de glicação avançada (AGEs no plasma de rato. Métodos: Ratos Wistar machos (10 semanas de idade, pesando 350 g foram designados para receber dieta de ração comercial (C; n = 8 animais/grupo, 5% de energia a partir de gordura ou dieta de cafeteria (CAF-D, n = 8 animais/grupo: 29% de energia de gordura e de sacarose em água (300 g/L de beber durante 6 semanas. Resultados: Índice de adiposidade em seis semanas foi maior no grupo CAF-D em comparação com C. O mesmo comportamento foi observado para os níveis plasmáticos de glicose, triglicerídeos, leptina, insulina e AGEs. A expressão do gene de IL-6 e TNF-α em tecido renal foi maior no grupo D-CAF e nenhuma diferença significativa no tecido adiposo. Não houve aumento destas citocinas no plasma ou rim. Houve uma diminuição significativa de adiponectina no grupo CAF-D. Conclusão: A exposição a curto prazo da CAF-D reflete alterações no metabolismo, aumento dos níveis plasmáticos de AGEs, o que pode refletir o aumento expressão de citocinas inflamatórias no rim.

  20. Effects of a post-weaning cafeteria diet in young rats: metabolic syndrome, reduced activity and low anxiety-like behaviour.

    Science.gov (United States)

    Lalanza, Jaume F; Caimari, Antoni; del Bas, Josep M; Torregrosa, Daniel; Cigarroa, Igor; Pallàs, Mercè; Capdevila, Lluís; Arola, Lluís; Escorihuela, Rosa M

    2014-01-01

    Among adolescents, overweight, obesity and metabolic syndrome are rapidly increasing in recent years as a consequence of unhealthy palatable diets. Animal models of diet-induced obesity have been developed, but little is known about the behavioural patterns produced by the consumption of such diets. The aim of the present study was to determine the behavioural and biochemical effects of a cafeteria diet fed to juvenile male and female rats, as well as to evaluate the possible recovery from these effects by administering standard feeding during the last week of the study. Two groups of male and female rats were fed with either a standard chow diet (ST) or a cafeteria (CAF) diet from weaning and for 8 weeks. A third group of males (CAF withdrawal) was fed with the CAF diet for 7 weeks and the ST in the 8th week. Both males and females developed metabolic syndrome as a consequence of the CAF feeding, showing overweight, higher adiposity and liver weight, increased plasma levels of glucose, insulin and triglycerides, as well as insulin resistance, in comparison with their respective controls. The CAF diet reduced motor activity in all behavioural tests, enhanced exploration, reduced anxiety-like behaviour and increased social interaction; this last effect was more pronounced in females than in males. When compared to animals only fed with a CAF diet, CAF withdrawal increased anxiety in the open field, slightly decreased body weight, and completely recovered the liver weight, insulin sensitivity and the standard levels of glucose, insulin and triglycerides in plasma. In conclusion, a CAF diet fed to young animals for 8 weeks induced obesity and metabolic syndrome, and produced robust behavioural changes in young adult rats, whereas CAF withdrawal in the last week modestly increased anxiety, reversed the metabolic alterations and partially reduced overweight.

  1. Application of InSAR and GIS Techniques to Ground Subsidence Assessment in the Nobi Plain, Central Japan

    Directory of Open Access Journals (Sweden)

    Minxue Zheng

    2013-12-01

    Full Text Available Spatial variation and temporal changes in ground subsidence over the Nobi Plain, Central Japan, are assessed using GIS techniques and ground level measurements data taken over this area since the 1970s. Notwithstanding the general slowing trend observed in ground subsidence over the plains, we have detected ground rise at some locations, more likely due to the ground expansion because of recovering groundwater levels and the tilting of the Nobi land mass. The problem of non-availability of upper-air meteorological information, especially the 3-dimensional water vapor distribution, during the JERS-1 observational period (1992–1998 was solved by applying the AWC (analog weather charts method onto the high-precision GPV-MSM (Grid Point Value of Meso-Scale Model water-vapor data to find the latter’s matching meteorological data. From the selected JERS-1 interferometry pair and the matching GPV-MSM meteorological data, the atmospheric path delay generated by water vapor inhomogeneity was then quantitatively evaluated. A highly uniform spatial distribution of the atmospheric delay, with a maximum deviation of approximately 38 mm in its horizontal distribution was found over the Plain. This confirms the effectiveness of using GPV-MSM data for SAR differential interferometric analysis, and sheds thus some new light on the possibility of improving InSAR analysis results for land subsidence applications.

  2. Investigation on Fuzzy Logic Based Centralized Control in Four-Port SEPIC/ZETA Bidirectional Converter for Photovoltaic Applications

    Directory of Open Access Journals (Sweden)

    VENMATHI, M.

    2016-02-01

    Full Text Available In this paper, a new four-port DC-DC converter topology is proposed to interface renewable energy sources and the load along with the energy storage device. The proposed four-port SEPIC/ZETA bidirectional converter (FP-SEPIC/ZETA BDC converter comprises an isolated output port with two unidirectional and one bidirectional input ports. This converter topology is obtained by the fusion of SEPIC/ZETA BDC and full-bridge converter. This converter topology ensures the non-reversal of output voltage hence it is preferred mostly for battery charging applications. In this work, photovoltaic (PV source is considered and the power balance in the system is achieved by means of distributed maximum power point tracking (DMPPT in the PV ports. The centralized controller is implemented using fuzzy logic controller (FLC and the performance is compared with conventional proportional integral (PI controller. The results offer useful information to obtain the desired output under line and load regulations. Experimental results are also provided to validate the simulation results.

  3. Application of InSAR and GIS Techniques to Ground Subsidence Assessment in the Nobi Plain, Central Japan

    Science.gov (United States)

    Zheng, Minxue; Fukuyama, Kaoru; Sanga-Ngoie, Kazadi

    2014-01-01

    Spatial variation and temporal changes in ground subsidence over the Nobi Plain, Central Japan, are assessed using GIS techniques and ground level measurements data taken over this area since the 1970s. Notwithstanding the general slowing trend observed in ground subsidence over the plains, we have detected ground rise at some locations, more likely due to the ground expansion because of recovering groundwater levels and the tilting of the Nobi land mass. The problem of non-availability of upper-air meteorological information, especially the 3-dimensional water vapor distribution, during the JERS-1 observational period (1992–1998) was solved by applying the AWC (analog weather charts) method onto the high-precision GPV-MSM (Grid Point Value of Meso-Scale Model) water-vapor data to find the latter's matching meteorological data. From the selected JERS-1 interferometry pair and the matching GPV-MSM meteorological data, the atmospheric path delay generated by water vapor inhomogeneity was then quantitatively evaluated. A highly uniform spatial distribution of the atmospheric delay, with a maximum deviation of approximately 38 mm in its horizontal distribution was found over the Plain. This confirms the effectiveness of using GPV-MSM data for SAR differential interferometric analysis, and sheds thus some new light on the possibility of improving InSAR analysis results for land subsidence applications. PMID:24385028

  4. Application of InSAR and GIS techniques to ground subsidence assessment in the Nobi Plain, Central Japan.

    Science.gov (United States)

    Zheng, Minxue; Fukuyama, Kaoru; Sanga-Ngoie, Kazadi

    2013-01-01

    Spatial variation and temporal changes in ground subsidence over the Nobi Plain, Central Japan, are assessed using GIS techniques and ground level measurements data taken over this area since the 1970s. Notwithstanding the general slowing trend observed in ground subsidence over the plains, we have detected ground rise at some locations, more likely due to the ground expansion because of recovering groundwater levels and the tilting of the Nobi land mass. The problem of non-availability of upper-air meteorological information, especially the 3-dimensional water vapor distribution, during the JERS-1 observational period (1992-1998) was solved by applying the AWC (analog weather charts) method onto the high-precision GPV-MSM (Grid Point Value of Meso-Scale Model) water-vapor data to find the latter's matching meteorological data. From the selected JERS-1 interferometry pair and the matching GPV-MSM meteorological data, the atmospheric path delay generated by water vapor inhomogeneity was then quantitatively evaluated. A highly uniform spatial distribution of the atmospheric delay, with a maximum deviation of approximately 38 mm in its horizontal distribution was found over the Plain. This confirms the effectiveness of using GPV-MSM data for SAR differential interferometric analysis, and sheds thus some new light on the possibility of improving InSAR analysis results for land subsidence applications. PMID:24385028

  5. Application of a process-based shallow landslide hazard model over a broad area in Central Italy

    Science.gov (United States)

    Gioia, Eleonora; Speranza, Gabriella; Ferretti, Maurizio; Godt, Jonathan W.; Baum, Rex L.; Marincioni, Fausto

    2015-01-01

    Process-based models are widely used for rainfall-induced shallow landslide forecasting. Previous studies have successfully applied the U.S. Geological Survey’s Transient Rainfall Infiltration and Grid-Based Regional Slope-Stability (TRIGRS) model (Baum et al. 2002) to compute infiltration-driven changes in the hillslopes’ factor of safety on small scales (i.e., tens of square kilometers). Soil data input for such models are difficult to obtain across larger regions. This work describes a novel methodology for the application of TRIGRS over broad areas with relatively uniform hydrogeological properties. The study area is a 550-km2 region in Central Italy covered by post-orogenic Quaternary sediments. Due to the lack of field data, we assigned mechanical and hydrological property values through a statistical analysis based on literature review of soils matching the local lithologies. We calibrated the model using rainfall data from 25 historical rainfall events that triggered landslides. We compared the variation of pressure head and factor of safety with the landslide occurrence to identify the best fitting input conditions. Using calibrated inputs and a soil depth model, we ran TRIGRS for the study area. Receiver operating characteristic (ROC) analysis, comparing the model’s output with a shallow landslide inventory, shows that TRIGRS effectively simulated the instability conditions in the post-orogenic complex during historical rainfall scenarios. The implication of this work is that rainfall-induced landslides over large regions may be predicted by a deterministic model, even where data on geotechnical and hydraulic properties as well as temporal changes in topography or subsurface conditions are not available.

  6. Application of a Central Composite Design for the Study of NOx Emission Performance of a Low NOx Burner

    Directory of Open Access Journals (Sweden)

    Marcin Dutka

    2015-04-01

    Full Text Available In this study, the influence of various factors on nitrogen oxides (NOx emissions of a low NOx burner is investigated using a central composite design (CCD approach to an experimental matrix in order to show the applicability of design of experiments methodology to the combustion field. Four factors have been analyzed in terms of their impact on NOx formation: hydrogen fraction in the fuel (0%–15% mass fraction in hydrogen-enriched methane, amount of excess air (5%–30%, burner head position (20–25 mm from the burner throat and secondary fuel fraction provided to the burner (0%–6%. The measurements were performed at a constant thermal load equal to 25 kW (calculated based on lower heating value. Response surface methodology and CCD were used to develop a second-degree polynomial regression model of the burner NOx emissions. The significance of the tested factors over their respective ranges has been evaluated using the analysis of variance and by the consideration of the coefficients of the model equation. Results show that hydrogen addition to methane leads to increased NOx emissions in comparison to emissions from pure methane combustion. Hydrogen content in a fuel is the strongest factor affecting NOx emissions among all the factors tested. Lower NOx formation because of increased excess air was observed when the burner was fuelled by pure methane, but this effect diminished for hydrogen-rich fuel mixtures. NOx emissions were slightly reduced when the burner head was shifted closer to the burner outer tube, whereas a secondary fuel stream provided to the burner was found to have no impact on NOx emissions over the investigated range of factors.

  7. On the optimal allocation of assets in investment portfolio with application of modern portfolio and nonlinear dynamic chaos theories in investment, commercial and central banks

    OpenAIRE

    Ledenyov, Dimitri O.; Ledenyov, Viktor O.

    2013-01-01

    The investment economy is a main characteristic of prosperous society. The investment portfolio management is a main financial problem, which has to be solved by the investment, commercial and central banks with the application of modern portfolio theory in the investment economy. We use the learning analytics together with the integrative creative imperative intelligent conceptual co-lateral adaptive thinking with the purpose to advance our scientific knowledge on the diversified investment ...

  8. SU-E-E-16: The Application of Texture Analysis for Differentiation of Central Cancer From Atelectasis

    Energy Technology Data Exchange (ETDEWEB)

    Gao, M; Fan, T; Duan, J [Shandong Tumor Hospital, Jinan, Shandong province (China)

    2015-06-15

    Purpose: Prospectively assess the potential utility of texture analysis for differentiation of central cancer from atelectasis. Methods: 0 consecutive central lung cancer patients who were referred for CT imaging and PET-CT were enrolled. Radiotherapy doctor delineate the tumor and atelectasis according to the fusion imaging based on CT image and PET-CT image. The texture parameters (such as energy, correlation, sum average, difference average, difference entropy), were obtained respectively to quantitatively discriminate tumor and atelectasis based on gray level co-occurrence matrix (GLCM) Results: The texture analysis results showed that the parameters of correlation and sum average had an obviously statistical significance(P<0.05). Conclusion: the results of this study indicate that texture analysis may be useful for the differentiation of central lung cancer and atelectasis.

  9. Gauss´s Mortality Formula: A Demometric Analysis with Application to the Feral Camel Population in Central Australia

    OpenAIRE

    Pflaumer, Peter

    2014-01-01

    A life table for the feral camel population in central Australia is constructed, using an extension of the Gompertz distribution, which was first proposed in a note by the famous mathematician Gauss. It is shown that under certain conditions some important life table parameters can be represented by simple formulae. The derived life table is then used to formulate both a continuous and a discrete model of the camel population. The models yield an annual growth rate of about 7%, a net reproduc...

  10. Study on Applications of Supply and Demand Theory of Microeconomics and Physics Field Theory to Central Place Theory

    OpenAIRE

    Nien, Benjamin Chih-Chien

    2006-01-01

    This paper attempts to analyze “central place theory” of spatial economics based on “supply and demand theory” in microeconomics and “field theory” in physics, and also discuss their relationship. Three most important research findings are described below. Firstly, the concept of market equilibrium could be expressed in the mathematical form of physics field theory under proper hypothesis. That is because the most important aspect of field theory model is that complex analysis is taken as a k...

  11. The giant Cafeteria roenbergensis virus that infects a widespread marine phagocytic protist is a new member of the fourth domain of Life.

    Directory of Open Access Journals (Sweden)

    Philippe Colson

    Full Text Available BACKGROUND: A recent work has provided strong arguments in favor of a fourth domain of Life composed of nucleo-cytoplasmic large DNA viruses (NCLDVs. This hypothesis was supported by phylogenetic and phyletic analyses based on a common set of proteins conserved in Eukarya, Archaea, Bacteria, and viruses, and implicated in the functions of information storage and processing. Recently, the genome of a new NCLDV, Cafeteria roenbergensis virus (CroV, was released. The present work aimed to determine if CroV supports the fourth domain of Life hypothesis. METHODS: A consensus phylogenetic tree of NCLDVs including CroV was generated from a concatenated alignment of four universal proteins of NCLDVs. Some features of the gene complement of CroV and its distribution along the genome were further analyzed. Phylogenetic and phyletic analyses were performed using the previously identified common set of informational genes present in Eukarya, Archaea, Bacteria, and NCLDVs, including CroV. FINDINGS: Phylogenetic reconstructions indicated that CroV is clearly related to the Mimiviridae family. The comparison between the gene repertoires of CroV and Mimivirus showed similarities regarding the gene contents and genome organization. In addition, the phyletic clustering based on the comparison of informational gene repertoire between Eukarya, Archaea, Bacteria, and NCLDVs unambiguously classified CroV with other NCLDVs and clearly included it in a fourth domain of Life. Taken together, these data suggest that Mimiviridae, including CroV, may have inherited a common gene content probably acquired from a common Mimiviridae ancestor. CONCLUSIONS: This further analysis of the gene repertoire of CroV consolidated the fourth domain of Life hypothesis and contributed to outline a functional pan-genome for giant viruses infecting phagocytic protistan grazers.

  12. Modern 'junk food' and minimally-processed 'natural food' cafeteria diets alter the response to sweet taste but do not impair flavor-nutrient learning in rats.

    Science.gov (United States)

    Palframan, Kristen M; Myers, Kevin P

    2016-04-01

    Animals learn to prefer and increase consumption of flavors paired with postingestive nutrient sensing. Analogous effects have been difficult to observe in human studies. One possibility is experience with the modern, processed diet impairs learning. Food processing manipulates flavor, texture, sweetness, and nutrition, obscuring ordinary correspondences between sensory cues and postingestive consequences. Over time, a diet of these processed 'junk' foods may impair flavor-nutrient learning. This 'flavor-confusion' hypothesis was tested by providing rats long-term exposure to cafeteria diets of unusual breadth (2 or 3 foods per day, 96 different foods over 3 months, plus ad libitum chow). One group was fed processed foods (PF) with added sugars/fats and manipulated flavors, to mimic the sensory-nutrient properties of the modern processed diet. Another group was fed only 'natural' foods (NF) meaning minimally-processed foods without manipulated flavors or added sugars/fats (e.g., fresh fruits, vegetables, whole grains) ostensibly preserving the ordinary correspondence between flavors and nutrition. A CON group was fed chow only. In subsequent tests of flavor-nutrient learning, PF and NF rats consistently acquired strong preferences for novel nutrient-paired flavors and PF rats exhibited enhanced learned acceptance, contradicting the 'flavor-confusion' hypothesis. An unexpected finding was PF and NF diets both caused lasting reduction in ad lib sweet solution intake. Groups did not differ in reinforcing value of sugar in a progressive ratio task. In lick microstructure analysis the NF group paradoxically showed increased sucrose palatability relative to PF and CON, suggesting the diets have different effects on sweet taste evaluation.

  13. The impact of cafeteria diet feeding on physiology and anxiety-related behaviour in male and female Sprague-Dawley rats of different ages.

    Science.gov (United States)

    Warneke, Wiebke; Klaus, Susanne; Fink, Heidrun; Langley-Evans, Simon C; Voigt, Jörg-Peter

    2014-01-01

    There is emerging experimental evidence that hyper-energetic diets not only cause obesity but also impact on behaviour in rodents. A hyper-energetic comfort diet/cafeteria diet (CD) fed during early development programmes anxiety-related behaviour in adult age, but little is known how an obesogenic CD impacts on behaviour when fed at a later age. To this end we fed CD to Sprague-Dawley rats of both sexes at either 6 weeks or 12 months old, for a period of 6 weeks. Anxiety-related behaviour was assessed in the elevated plus maze (EPM) and the open field (OF). A glucose tolerance test was performed and metabolic indices, body weight and fat were measured. CD-fed young adult females, but not males, had a higher energy intake, due to an overconsumption of carbohydrates and fats. Only in adult CD-fed rats of both sexes did this overconsumption led to increased weight gain. Protein intake was reduced in all CD groups. Fat mass (subcutaneous, perirenal, gonadal) increased in most CD groups, whereas brown fat increased only in adults. Triacylglycerol, free fatty acid and total cholesterol concentrations increased predominantly in adult CD-fed rats. Glucose tolerance was only impaired in adult males. CD-fed adult males showed fewer entries into the aversive open arms and groomed more on the EPM, whereas adult females spent more time on these arms. In the OF, CD-fed females of both ages visited the inner zone more frequently and travelled a longer distance. The behavioural data suggests anxiolysis in CD-fed females and signs of increased anxiety in adult males. In conclusion, this study demonstrates that feeding CD leads to both obesity and behavioural changes in rats. Overall, these effects were more pronounced in older rats, with the behavioural effects being particularly gender dependent.

  14. Evidences of basal lactate production in the main white adipose tissue sites of rats. Effects of sex and a cafeteria diet.

    Science.gov (United States)

    Arriarán, Sofía; Agnelli, Silvia; Sabater, David; Remesar, Xavier; Fernández-López, José Antonio; Alemany, Marià

    2015-01-01

    Female and male adult Wistar rats were fed standard chow or a simplified cafeteria diet for one month. Then, the rats were killed and the white adipose tissue (WAT) in four sites: perigonadal, retroperitoneal, mesenteric and subcutaneous (inguinal) were sampled and frozen. The complete WAT weight in each site was measured. Gene expression analysis of key lipid and glucose metabolism enzymes were analyzed, as well as tissue and plasma lactate and the activity of lactate dehydrogenase. Lactate gradients between WAT and plasma were estimated. The influence of sex and diet (and indirectly WAT mass) on lactate levels and their relationships with lactate dehydrogenase activity and gene expressions were also measured. A main conclusion is the high production of lactate by WAT, practically irrespective of site, diet or sex. Lactate production is a direct correlate of lactate dehydrogenase activity in the tissue. Furthermore, lactate dehydrogenase activity is again directly correlated with the expression of the genes Ldha and Ldhb for this enzyme. In sum, the ability to produce lactate by WAT is not directly dependent of WAT metabolic state. We postulate that, in WAT, a main function of the lactate dehydrogenase path may be that of converting excess available glucose to 3C fragments, as a way to limit tissue self-utilization as substrate, to help control glycaemia and/or providing short chain substrates for use as energy source elsewhere. More information must be gathered before a conclusive role of WAT in the control of glycaemia, and the full existence of a renewed glucose-lactate-fatty acid cycle is definitely established. PMID:25741703

  15. Bergamot polyphenol fraction prevents nonalcoholic fatty liver disease via stimulation of lipophagy in cafeteria diet-induced rat model of metabolic syndrome.

    Science.gov (United States)

    Parafati, Maddalena; Lascala, Antonella; Morittu, Valeria Maria; Trimboli, Francesca; Rizzuto, Antonia; Brunelli, Elvira; Coscarelli, Francesca; Costa, Nicola; Britti, Domenico; Ehrlich, James; Isidoro, Ciro; Mollace, Vincenzo; Janda, Elzbieta

    2015-09-01

    Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in industrialized countries. Defective autophagy of lipid droplets (LDs) in hepatocytes, also known as lipophagy, has recently been identified as a possible pathophysiological mechanism of NAFLD. Experimental and epidemiological evidence suggests that dietary polyphenols may prevent NAFLD. To address this hypothesis and analyze the underlying mechanisms, we supplemented bergamot polyphenol fraction (BPF) to cafeteria (CAF) diet-fed rats, a good model for pediatric metabolic syndrome and NAFLD. BPF treatment (50 mg/kg/day supplemented with drinking water, 3 months) potently counteracted the pathogenic increase of serum triglycerides and had moderate effects on blood glucose and obesity in this animal model. Importantly, BPF strongly reduced hepatic steatosis as documented by a significant decrease in total lipid content (-41.3% ± 12% S.E.M.), ultrasound examination and histological analysis of liver sections. The morphometric analysis of oil-red stained sections confirmed a dramatic reduction in LDs parameters such as total LD area (48.5% ± 15% S.E.M.) in hepatocytes from CAF+BPF rats. BPF-treated livers showed increased levels of LC3 and Beclin 1 and reduction of SQSTM1/p62, suggesting autophagy stimulation. Consistent with BPF stimulation of lipophagy, higher levels of LC3II were found in the LD subcellular fractions of BPF-expose livers. This study demonstrates that the liver and its lipid metabolism are the main targets of bergamot flavonoids, supporting the concept that supplementation of BPF is an effective strategy to prevent NAFLD. PMID:26025327

  16. Evidences of basal lactate production in the main white adipose tissue sites of rats. Effects of sex and a cafeteria diet.

    Directory of Open Access Journals (Sweden)

    Sofía Arriarán

    Full Text Available Female and male adult Wistar rats were fed standard chow or a simplified cafeteria diet for one month. Then, the rats were killed and the white adipose tissue (WAT in four sites: perigonadal, retroperitoneal, mesenteric and subcutaneous (inguinal were sampled and frozen. The complete WAT weight in each site was measured. Gene expression analysis of key lipid and glucose metabolism enzymes were analyzed, as well as tissue and plasma lactate and the activity of lactate dehydrogenase. Lactate gradients between WAT and plasma were estimated. The influence of sex and diet (and indirectly WAT mass on lactate levels and their relationships with lactate dehydrogenase activity and gene expressions were also measured. A main conclusion is the high production of lactate by WAT, practically irrespective of site, diet or sex. Lactate production is a direct correlate of lactate dehydrogenase activity in the tissue. Furthermore, lactate dehydrogenase activity is again directly correlated with the expression of the genes Ldha and Ldhb for this enzyme. In sum, the ability to produce lactate by WAT is not directly dependent of WAT metabolic state. We postulate that, in WAT, a main function of the lactate dehydrogenase path may be that of converting excess available glucose to 3C fragments, as a way to limit tissue self-utilization as substrate, to help control glycaemia and/or providing short chain substrates for use as energy source elsewhere. More information must be gathered before a conclusive role of WAT in the control of glycaemia, and the full existence of a renewed glucose-lactate-fatty acid cycle is definitely established.

  17. Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet.

    Science.gov (United States)

    Vickers, Steven P; Cheetham, Sharon C; Headland, Katie R; Dickinson, Keith; Grempler, Rolf; Mayoux, Eric; Mark, Michael; Klein, Thomas

    2014-01-01

    The present study assessed the potential of the sodium glucose-linked transporter (SGLT)-2 inhibitor empagliflozin to decrease body weight when administered alone or in combination with the clinically effective weight-loss agents orlistat and sibutramine in obese rats fed a cafeteria diet. Female Wistar rats were exposed to a cafeteria diet to induce obesity. Empagliflozin was dosed once daily (10, 30, and 60 mg/kg) for 28 days. Combination studies were subsequently performed using a submaximal empagliflozin dose (10 mg/kg) with either sibutramine or orlistat. Body weight, food, and water intake were recorded daily. The effect of drug treatment on glucose tolerance, relevant plasma parameters, and carcass composition was determined. Empagliflozin dose-dependently reduced body weight, plasma leptin, and body fat though increased urinary glucose excretion. The combination of empagliflozin and orlistat significantly reduced body weight compared to animals treated with either drug alone, and significantly improved glucose tolerance, plasma insulin, and leptin compared to vehicle-treated controls. The effect of sibutramine to improve glycemic control in an oral glucose-tolerance test was also significantly increased, with empagliflozin and combination treatment leading to a reduction in carcass fat greater than that observed with either drug alone. These data demonstrate that empagliflozin reduces body weight in cafeteria-fed obese rats. In combination studies, empagliflozin further improved the body-weight or body-fat loss of animals in comparison to orlistat or sibutramine alone. Such studies may indicate improved strategies for the treatment of obese patients with prediabetes or type 2 diabetes. PMID:25061325

  18. Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet

    Directory of Open Access Journals (Sweden)

    Vickers SP

    2014-07-01

    Full Text Available Steven P Vickers,1 Sharon C Cheetham,1 Katie R Headland,1 Keith Dickinson,1 Rolf Grempler,2 Eric Mayoux,2 Michael Mark,2 Thomas Klein2 1RenaSci, BioCity Nottingham, Nottingham, UK; 2Boehringer Ingelheim Pharma, Biberach an der Riss, Germany Abstract: The present study assessed the potential of the sodium glucose-linked transporter (SGLT-2 inhibitor empagliflozin to decrease body weight when administered alone or in combination with the clinically effective weight-loss agents orlistat and sibutramine in obese rats fed a cafeteria diet. Female Wistar rats were exposed to a cafeteria diet to induce obesity. Empagliflozin was dosed once daily (10, 30, and 60 mg/kg for 28 days. Combination studies were subsequently performed using a submaximal empagliflozin dose (10 mg/kg with either sibutramine or orlistat. Body weight, food, and water intake were recorded daily. The effect of drug treatment on glucose tolerance, relevant plasma parameters, and carcass composition was determined. Empagliflozin dose-dependently reduced body weight, plasma leptin, and body fat though increased urinary glucose excretion. The combination of empagliflozin and orlistat significantly reduced body weight compared to animals treated with either drug alone, and significantly improved glucose tolerance, plasma insulin, and leptin compared to vehicle-treated controls. The effect of sibutramine to improve glycemic control in an oral glucose-tolerance test was also significantly increased, with empagliflozin and combination treatment leading to a reduction in carcass fat greater than that observed with either drug alone. These data demonstrate that empagliflozin reduces body weight in cafeteria-fed obese rats. In combination studies, empagliflozin further improved the body-weight or body-fat loss of animals in comparison to orlistat or sibutramine alone. Such studies may indicate improved strategies for the treatment of obese patients with prediabetes or type 2 diabetes. Keywords

  19. Central Asia in a Changing World: From a Peripheral Region to an Area of Policy Generation and Application. Actors, Policy and Security

    Directory of Open Access Journals (Sweden)

    Nora Sainz Gsell

    2005-10-01

    Full Text Available This work deals with Central Asia, beginning with an analysis of the characteristics of international insertion of the area as a whole and of the former Soviet republics that comprise it. In a general way, it aims to analyse the evolution of Central Asia from a peripheral region to an area that generates behaviours and receives the application of policies on the part ofinternational actors. In the first part of the study, it mentions a series of particularities of the republics that have determined the relationships in the region(the Central Asian order and those between the region and the outside world; it indicates geo-historical and economic-strategic aspects. In the second part, it examines the foreign policy of the republics in the post-Cold War era from the singularities of domestic policy. And, in the third part, it analyses, according to the aforementioned peculiarities, the policies that the area and each State has generated in international actors, both regional ones and global ones, and which have transformed the region from a peripheral one to a geopolitically emerging one.

  20. A functional central limit theorem for branching random walks, almost sure weak convergence, and applications to random trees

    OpenAIRE

    Grübel, Rudolf; Kabluchko, Zakhar

    2014-01-01

    Let $W_{\\infty}(\\beta)$ be the limit of the Biggins martingale $W_n(\\beta)$ associated to a supercritical branching random walk with mean number of offspring $m$. We prove a functional central limit theorem stating that as $n\\to\\infty$ the process $$ D_n(u):= m^{\\frac 12 n} \\left(W_{\\infty}\\left(\\frac{u}{\\sqrt n}\\right) - W_{n}\\left(\\frac{u}{\\sqrt n}\\right) \\right) $$ converges weakly, on a suitable space of analytic functions, to a Gaussian random analytic function with random variance. Usin...

  1. CLOSURE OF SMALL CENTRAL PERFORATIONS OF TYMPANIC MEMBRANE WITH GELFILM PATCH AND APPLICATION OF PLATELET RICH PLASMA VERSUS CHEMICAL CAUTERIZATION: A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    Jeena Kunnathully

    2016-03-01

    Full Text Available BACKGROUND Small central perforation of tympanic membrane is a common finding in patients approaching Otolaryngologists. Even though tympanoplasty can provide a disease free ear and restore hearing loss, most of these cases are either left alone or not surgically treated due to lack of patient compliance. OBJECTIVES In the present study conducted in the Department of Otolaryngology and Head and Neck Surgery, Academy of Medical Sciences, Pariyaram, Kerala, India, we have compared the results of two office procedures for closure of small central perforations. STUDY DESIGN Randomised control trial. METHODS Out of 35 cases with small central perforations of tympanic membrane, 18 were subjected to chemical cauterization with Gelfoam patching and 17 underwent freshening with application of Gelfilm patch and Platelet Rich Plasma (PRP. RESULTS Results were measured in terms of healing of perforation and hearing gain at the end of 3 months. Complete closure was achieved in 54% for chemical cauterization and 53% for Gelfilm patching. The mean hearing gain was 2.17 dB and 2.29 dB respectively. CONCLUSION Smaller size, traumatic aetiology and antero-inferior locations of tympanic membrane perforation showed better results, whereas larger perforations, comorbidities like diabetes mellitus and posteroinferior locations showed poorer results. The complications noted were vertigo, more in chemical cauterization group and otomycosis, more in the freshening and Gelfilm patching group. We thus conclude that all cases of dry small central perforations should be given a trial of either of these cost effective nonsurgical methods before resorting to surgery, depending upon patient compliance.

  2. GIS Applications in Land Management: The Loss of High Quality Land to Development in Central Mississippi from 1987-2002

    Directory of Open Access Journals (Sweden)

    Edmund C. Merem

    2005-08-01

    Full Text Available The socio-economic trends and history of Central Mississippi reveal a major rural influence based upon a dependence on agricultural activities as part of the economic engine driving the state’s economy. Yet, in the last several years, the amount of agricultural land in the counties continues to decline. Similar changes in other variables associated with agricultural land use and the continuity of farming in the state have also been changing. Indeed, under the pressure of urban growth, some farmers are forced to use less productive soils or have abandoned the agricultural business. Considering the gravity of the problem and the implications for sustainable development, public concern has increased in the state of Mississippi that urbanization and other factors may be eroding potential farmland. Given the effects of the current trends on the future capacity to produce food items, there are concerns that the growing incidence of farmland loss may also erode the basis for sustainable use of agricultural land, biodiversity and protection of the state’s ecological treasures. Notwithstanding the gravity of these trends, no major effort in the literature has aimed at documenting the incidence of agricultural land loss and the linkages to urbanization in the region of Central Mississippi. What changes have taken place in the size of agricultural land within the counties and what factors are responsible for it? This paper examines the issue of farmland loss in Central Mississippi with a focus at the county level between 1987 and 2002 from a temporal-spatial perspective. In terms of methodology, the paper uses a mixed scale approach based upon the existing literature. Data were drawn from the United States Census databases of Population and Agriculture. This information is analyzed with basic descriptive statistics and GIS with particular attention to the spatial trends at the county level. Results indicate that the counties under

  3. 中央热送风冲天炉的应用%Application of Central Blast-heating Cupola

    Institute of Scientific and Technical Information of China (English)

    冯英宇; 苏文生

    2011-01-01

    为提高冲天炉的综合性能,通过采取中央集中送风,合理控制风口风速,合理的炉膛结构,防止风嘴熔化等措施.强化焦炭燃烧,增加了焦炭的燃烧比,提高了冲天炉熔炼铁液的出炉温度;能适用混合焦炭,简化了焦炭处理;使炉衬侵蚀减小,修炉简便.通过多年实践改进,完善了中央送风冲天炉的相关工艺参数.该炉型操作简单,有利于降低硅、锰烧损和节能,打炉方便,生产稳定,可在同行业推广.%To improve the overall performance of cupola, taking the measures of centralized air supply, reasonable air control speed, reasonable furnace structurc and preventing the tuyere from mclting, the process of coke combustion is enhanced, the combustion ratio of coke increases and the tapping temperature of cupola melting iron improves. Mixed coke can be applied under the above measures, so the coke processing is simplified, which reduces lining erosion, makes repairing furnace simple. Through practicing and improving in years, the relevant process parameters of central blast-heating cupola are perfected. The cupola is simple in work and stable in production, which can reduce silicon-manganese melting loss and save energy. The cupola is worth of spreading in the same industry.

  4. 河南省部分农村寄宿制中小学校食堂卫生学评价%Cafeterias hygienic evaluation of rural boarding school of Henan Province

    Institute of Scientific and Technical Information of China (English)

    梁利花; 吴翠平; 娄晓民; 彭玉林; 郭蔚蔚; 李岚

    2011-01-01

    Objective To investigate infrastructure and hygienic situation of rural boarding school cafeterias in Henan province and to explore corresponding solutions for improving the hygienic conditions. Methods Totally 60 boarding schools from each of the three type areas, which included economically developed counties, moderately developed counties and developing counties, were selected and cafeterias conditions of 180 boarding schools were evaluated and analyzed ,which included the facilities and equipment layout conditions, environmental hygiene conditions, food and raw materials procurement, storage and processing situations, employees in health status and cafeteria supervision and management etc. Results The fitting rate of separate functional partition, adequate non-slip on the ground and the "three defenses" facilities in operating rooms was 25. 4%, 20.3% and 19.2%, respectively. The qualified rate of tableware store, special washing facilities, the health permit asked in the procurement of food and raw materials obtained, foodand raw materials standard storage, the remaining food frozen was 37.3%, 44. 1%, 36.7% ,53.1% and 57.6%, respectively. The passing rates of employees health each indicators and several key indlcators of cafeteria supervision and management were above 80%. Conclusion Cafeteria equipments of rural boarding schools are inadequate and the arrangemont is not standard, the procurement, preservation and processing of food and raw materials are lack of standardized, and the supervision and management system put into effect invalidly.%目的 了解河南省农村寄宿制学校食堂的基础设施卫生及食品安全状况,探索存在的问题及相应的解决方案.方法 在经济较发达县、中等发达县及欠发达县各选取60所寄宿制学校,共计180所,对所选学校食堂设施布局及环境卫生,食品及原料采购、贮存及加工,从业人员卫生,食堂监督管理等进行卫生学评价.结果 食堂

  5. Application of the viscosity-expansion method to a rotating thin fluid disk bound by central gravity

    Science.gov (United States)

    Takahashi, Koichi

    2015-07-01

    The 2D rotation of a thin fluid disk with a porous sink around the center is studied within the Navier-Stokes and Euler equations. The viscosity (ν)-expansion method is applied to the viscous fluid bound to the central mass via gravity. The Navier-Stokes equations yield various types of rotation curve, including a flat one, depending on the choice of the pressure function that is not determined within the fluid dynamics. Stationary flow is achieved through the balance of the pressure gradient, gravity, and the centrifugal force. These features of the stationary flow survive in the inviscid limit. The stability of the inviscid flow is examined by the Euler equations for the perturbations. At large distances, the real part of eigenfrequencies (EFs) are dominantly positive and decreasing with distance for flat and rising rotation curves, meaning that the spiral pattern of the perturbations is trailing. One real increasing EF exists for the decaying rotation curve, for which the spiral pattern is leading. Complex frequencies always emerge when the disk has m-fold rotational symmetry with m≥ 2. The shape of the perturbed rotation curve has azimuthal as well as temporal dependences.

  6. Ground-water temperature of the Wyoming quadrangle in central Delaware : with application to ground-water-source heat pumps

    Science.gov (United States)

    Hodges, Arthur L.

    1982-01-01

    Ground-water temperature was measured during a one-year period (1980-81) in 20 wells in the Wyoming Quadrangle in central Delaware. Data from thermistors set at fixed depths in two wells were collected twice each week, and vertical temperature profiles of the remaining 18 wells were made monthly. Ground-water temperature at 8 feet below land surface in well Jc55-1 ranged from 45.0 degrees F in February to 70.1 degrees F in September. Temperature at 35 feet below land surface in the same well reached a minimum of 56.0 degrees F in August, and a maximum of 57.8 degrees F in February. Average annual temperature of ground water at 25 feet below land surface in all wells ranged from 54.6 degrees F to 57.8 degrees F. Variations of average temperature probably reflect the presence or absence of forestation in the recharge areas of the wells. Ground-water-source heat pumps supplied with water from wells 30 or more feet below land surface will operate more efficiently in both heating and cooling modes than those supplied with water from shallower depths. (USGS)

  7. Application of central composite design to optimize the amount of carbon source and prebiotics for Bifidobacterium bifidum BB01

    Directory of Open Access Journals (Sweden)

    Shu Guowei

    2016-06-01

    Full Text Available The objective of the present study was to obtain the optimum proportion of the carbon source and prebiotics for Bifidobacterium bifidum BB01 by the central composite design (CCD. The effect of carbon source (lactose and two prebiotics (inulin and fructooligosaccharides on the BB01 were observed by measuring the OD600 value, pH value and the viable counts at 18h. The final optimized concentrations of carbon source and prebiotics were: lactose 1.6%, inulin 0.26%, and fructooligosaccharides 0.22%. The result indicates that the growth of B. bifidum BB01 shows an significant increase in the optimized culture medium (p < 0.05, the OD600 value reached 1.434 at 18h, which increased 6.58% compared to the control. And the viable counts of B. bifidum BB01 increased 24.36% and reached (2.17±0.06 ×109cfu/mL. The results show that the optimization of the carbon source and prebiotics using CCD in this study is workable and necessary.

  8. Application of Response Surface Methodology and Central Composite Inscribed Design for Modeling and Optimization of Marble Surface Quality

    Directory of Open Access Journals (Sweden)

    Sümeyra Cevheroğlu Çıra

    2016-01-01

    Full Text Available Factors affecting the final surface quality of polished marble are not yet fully understood. Clarifying these factors for optimization of multivariate polishing process by trial and error method is difficult, time-consuming, and costly task. In this study, the empirical practices were carried out using an experimental design, specifically, a central composite inscribed (CCI design. The factors considered in CCI design were belt speed, rotational speed, and pressure of the polishing head, and the responses were surface glossiness and roughness. Mathematical models describing responses were produced using experimental datasets, and analysis of variance (ANOVA was used to assess the fit of the models generated with the experimental data. For process optimization, desirability function analysis (DFA was used. This study has shown that the CCI could efficiently be applied for the modelling of polishing machine for surface quality of marble strips. Better surface quality generally resulted from lower belt speeds, which increased contact time between the abrasives and strips. Optimized surface quality for marble specimen was established.

  9. Application of IEUBK model in lead risk assessment of children aged 61-84 months old in central China.

    Science.gov (United States)

    Li, Yanyan; Hu, Jia; Wu, Wei; Liu, Shuyun; Li, Mei; Yao, Na; Chen, Jianwei; Ye, Linxiang; Wang, Qi; Zhou, Yikai

    2016-01-15

    Few studies have focused on the accuracy of using the Integrated Exposure Uptake Biokinetic (IEUBK) model in Chinese children with site- and age-specific exposure data. This study aimed to validate the accuracy and sensitivity of the IEUBK model in lead risk assessment of Chinese children aged 61-84 months old. A total of 760 children were enrolled from two respective counties in Central China by using random cluster sampling method. Blood lead levels (BLLs) of all subjects were determined using graphite furnace atomic absorption spectrometry, as well as that in the environmental media, such as air, drinking water, soil, dust and food. Age- and site-specific time-activity patterns and water consumption were evaluated by using questionnaires for children. Exposure parameters including outdoor and indoor activity time, ventilation rate and water consumption in this study were different from the default values of the IEUBK model. Statistical analysis revealed no significant differences between the predicted and observed BLLs. Diet and soil/dust lead intake contributed approximately 83.39% (57.40%-93.84% range) and 15.18% (3.25%-41.60% range) of total lead intake, respectively. These findings showed that the IEUBK model is suitable for lead risk assessment of Chinese children aged 61-84 months old and diet acts as an important lead source. PMID:26433329

  10. Application of microtremor array measurements to delineate S-wave velocity structures in Bangkok Basin, central Thailand

    Science.gov (United States)

    Hayashi, K.; Pananont, P.; Wongpanit, T.; Habangkham, S.

    2014-12-01

    The Bangkok Basin, located in the lower part of the Chao Phraya River Basin in central Thailand contains very thick sediment and are often affected by the large distant earthquakes due to local site amplification. Shear wave velocities (Vs) measurements have been performed at five sites in the Bangkok Basin (Figure 1) by a two-station spatial autocorrelation method (2ST-SPAC) using long-period accelerometers. Receiver separation varied from 5 to 2,100m and maximum separation (array size) varied from 1,800 to 2,100 m. In each separation, 10 to 90 minutes ambient noise was recorded with sampling interval of 10 ms. Due to the security concern, data acquisition was performed in the day-time and in relatively quiet places such as in parks or less densely residential areas. A spatial autocorrelation was used for calculating phase velocity and clear dispersion curves were obtained in frequency range from about 0.3 to 10 Hz. Minimum frequency and corresponding maximum wavelength ranged from 0.32 to 0.48 Hz and about 2,180 to 5,140 m, depending on the site. An inversion consisting of a least squares method and a Genetic Algorithm was used to estimate Vs profiles from the dispersion curves to a depth of about 1,000 to 2,500 m depending on the sites. Figure 2 shows comparison of Vs profiles obtained by the inversion. We can see that a low velocity layer with Vs lower than 400 m/s exists between depths of 0 to 200 m at all sites. Intermediate bedrock with Vs higher than 1,000 m/s exists between depths of 240 to 1,250 m. Deepest bedrock with Vs higher than 2,000 m/s seems to exist at a depth of at least 1,600 m.

  11. DEVELOPMENT OF A GENERAL RELATIVISTIC MAGNETOHYDRODYNAMIC CODE AND ITS APPLICATION TO THE CENTRAL ENGINE OF LONG GAMMA-RAY BURSTS

    International Nuclear Information System (INIS)

    In order to investigate the formation of relativistic jets at the center of a progenitor of a gamma-ray burst (GRB), we develop a two-dimensional general relativistic magnetohydrodynamic code. We show that the code passes many well-known test calculations, and confirm the reliability of the code. Then we perform a numerical simulation of a collapsar using a realistic progenitor model. It is shown that a jet is launched from the center of the progenitor. The structure of the jet is similar to the previous study: a Poynting flux jet is surrounded by the funnel-wall jet. Even at the final stage of the simulation, the bulk Lorentz factor of the jet is still low, and the total energy of the jet is still as small as 1048 erg. However, we find that the energy flux per unit rest-mass flux is as high as 102 at the bottom of the jet. Thus, we conclude that the bulk Lorentz factor of the jet can be potentially high when it propagates outward. Also, as long as the duration of the activity of the central engine is long enough, the total energy of the jet can be large enough to explain the typical explosion energy of a GRB (∼1051 erg). It is shown that the outgoing Poynting flux exists at the horizon around the polar region, which proves that the Blandford-Znajek mechanism is really working. However, we conclude that the jet is mainly launched by the magnetic field amplified by the gravitational collapse and differential rotation around the black hole, rather than the Blandford-Znajek mechanism.

  12. Modeling volcanic ash resuspension – application to the 14–18 October 2011 outbreak episode in Central Patagonia, Argentina

    Directory of Open Access Journals (Sweden)

    A. Folch

    2013-09-01

    Full Text Available Volcanic fallout deposits from the June 2011 Cordón Caulle eruption in Central Patagonia were remobilized in several occasions months after their emplacement. In particular, during 14–18 October 2011, an intense outbreak episode generated huge volcanic clouds that were dispersed across Argentina, causing multiple impacts in the environment, affecting the air quality and disrupting airports. Fine ash particles in volcanic fallout deposits can be resuspended under favourable meteorological conditions, particularly during strong wind episodes in arid environments having low soil moisture and poor vegetation coverage. In opposition to eruption-formed ash clouds, modeling of resuspension-formed ash clouds has received little attention. In consequence, there are no emission schemes specially developed and calibrated for volcanic ash, and no operational product exists to model and forecast the formation and dispersal of resuspension ash clouds. Here we implement three dust emission schemes of increasing complexity in the FALL3D tephra dispersal model and use the 14–18 October 2011 outbreak episode as a model test case. We calibrate the emission schemes and validate the results of the coupled WRF-ARW/FALL3D modeling system using satellite imagery and measurements of visibility (a quantity related to total suspended particle concentration at surface and particulate matter (PM10 concentration at several meteorological and air quality stations sparse across Argentina and Uruguay. Our final goal is to test the capability of the modeling system to become, in the near future, an operational forecast product for volcanic ash resuspension events.

  13. The Central Point and Applicant of DHI%DHI技术的关键点及数据应用分析

    Institute of Scientific and Technical Information of China (English)

    赵秀新; 李建斌; 侯明海; 仲跻峰

    2014-01-01

    奶牛生产性能测定(DairyHerdImprovement,DHI),又称奶牛群改良,旨在对奶牛泌乳性能及乳成分进行测定并建立完整的记录体系,也是奶牛数字化育种技术的核心和基础。通过应用DHI技术为奶农提供指导服务,可以产生巨大的经济效益;其次,还可以为青年公牛后裔测定、种子母牛群组建、选种选配等育种工作提供数据支持。本文对DHI技术的关键点和报告解读技巧进行综述,以期指导生产实践。%Dairy herd improvement (DHI), establish a formal record system for the lactation performance and milk composition of dairy cattle. It is the basic and central system for dairy cattle digital breeding. A huge economical beneift can be achieved by the application of DHI for dairy farmers. It also makes a huge contribution for progency test of youngbull, elite cow herd building, selection and mating. This article is going to discuss the central point of DHI test for implementation.

  14. Profile of central research and application laboratory of Aǧrı İbrahim Çeçen University

    Science.gov (United States)

    Türkoǧlu, Emir Alper; Kurt, Murat; Tabay, Dilruba

    2016-04-01

    Aǧrı İbrahim Çeçen University built a central research and application laboratory (CRAL) in the east of Turkey. The CRAL possesses 7 research and analysis laboratories, 12 experts and researchers, 8 standard rooms for guest researchers, a restaurant, a conference hall, a meeting room, a prey room and a computer laboratory. The CRAL aims certain collaborations between researchers, experts, clinicians and educators in the areas of biotechnology, bioimagining, food safety & quality, omic sciences such as genomics, proteomics and metallomics. It also intends to develop sustainable solutions in agriculture and animal husbandry, promote public health quality, collect scientific knowledge and keep it for future generations, contribute scientific awareness of all stratums of society, provide consulting for small initiatives and industries. It has been collaborated several scientific foundations since 2011.

  15. Multi-modeling assessment of recent changes in groundwater resource: application to the semi-arid Haouz plain (Central Morocco)

    Science.gov (United States)

    Fakir, Younes; Brahim, Berjamy; Page Michel, Le; Fathallah, Sghrer; Houda, Nassah; Lionel, Jarlan; Raki Salah, Er; Vincent, Simonneaux; Said, Khabba

    2015-04-01

    The Haouz plain (6000 km2) is a part of the Tensift basin located in the Central Morocco. The plain has a semi-arid climate (250 mm/y of rainfall) and is bordered in the south by the High-Atlas mountains. Because the plain is highly anthropized, the water resources face heavy demands from various competing sectors, including agriculture (over than 273000 ha of irrigated areas), water supply for more than 2 million inhabitants and about 2 millions of tourists annually. Consequently the groundwater is being depleted on a large area of the plain, with problems of water scarcity which pose serious threats to water supplies and to sustainable development. The groundwater in the Haouz plain was modeled previously by MODFLOW (USGS groundwater numerical modeling) with annual time steps. In the present study a multi-modeling approach is applied. The aim is to enhance the evaluation of the groundwater pumping for irrigation, one of the most difficult data to estimate, and to improve the water balance assessment. In this purpose, two other models were added: SAMIR (Satellite Estimation of Agricultural Water Demand) and WEAP (integrated water resources planning). The three models are implemented at a monthly time step and calibrated over the 2001-2011 period, corresponding to 120 time steps. This multi-modeling allows assessing the evolution of water resources both in time and space. The results show deep changes during the last years which affect generally the water resources and groundwater particularly. These changes are induced by a remarkable urbanism development, succession of droughts, intensive agriculture activities and weak management of irrigation and water resources. Some indicators of these changes are as follow: (i) the groundwater table decrease varies between 1 to 3m/year, (ii) the groundwater depletion during the last ten year is equivalent to 50% of the lost reserves during 40 years, (iii) the annual groundwater deficit is about 100 hm3, (iv) the renewable

  16. A METHOD OF SUPERIMPOSED TRIANGULATIONS FOR CALCULATION OF VELOCITY GRADIENT OF HORIZONTAL MOVEMENTS: APPLICATION TO THE CENTRAL ASIAN GPS NETWORK

    Directory of Open Access Journals (Sweden)

    Alexander V. Zubovich

    2015-09-01

    Full Text Available A new method is proposed to define piecewise continuous fields of velocity gradients of recent horizontal movements of the Earth’s crust from spatially discrete data on horizontal velocities of such movements. The method is designed to identify spatial inhomogeneities in the field of horizontal strain rates (e.g., zones of localized deformation and boundaries between areas with different strain rates in considerable detail. It is applied to determine the field of horizontal velocity gradient in the region of the Central Asian GPS network which covers vast territories of the Kyrgyz Tien-Shan and Pamirs mountain ranges, the T arim depression, and the Kazakh Shield (Fig. 1. Calculations are based on GPS survey data obtained at 308 sites from 1995 to 2006 (Fig. 4. The resolution of the proposed method is increased by using a triangulation grid which is much denser than a conventional one (Fig. 2 and 3. As a result, point x on the surface under study is covered by several triangles rather than one (Fig. 5. Strain characteristics at point x are calculated by weighted summation of corresponding characteristics in the cover triangles. Thus, for each point we estimate spin tensor W, which defines angular velocity ω, and components of horizontal strain rate tensor E. These components provide for direct calculation of orientation of principal axes and invariants of E, i.e. maximum stretching E1, maximum shortening E2, velocity divergence E=E1+E2, and maximum shear rates Γ=⎪E1−E2⎪/2 (Fig. 6 to 11. The calculated values are presented in maps which demonstrate that spatial distribution of such values is highly inhomogeneous. Regions with increased values of kinematic characteristics mentioned above stand out sharply against the background. At the same time, spatial distribution of the kinematical characteristics in the Tien Shan region is quite regular: zones of increased absolute values of E2 are mainly oriented in the ENE direction, while the NNW

  17. Vulnerability assessment of karst aquifer feeding Pertuso Spring (Central Italy): comparison between different applications of COP method

    Science.gov (United States)

    Sappa, Giuseppe; Ferranti, Flavia; Luciani, Giulia

    2016-04-01

    Vulnerability assessment of karst aquifers and vulnerability mapping are important tools for improved sustainable management and protection of karst groundwater resources. In this paper, to estimate the vulnerability degree of the karst aquifer feeding Pertuso Spring in Central Italy, two different implementations of COP method, supported by an open source GIS, were tested and a comparison of the vulnerability maps is proposed. The study area is a highly karstified carbonate aquifer located in the Upper Valley of the Aniene River, in the south-east part of Latium Region. The hydrogeological basin covers about 50 km2 and the karst aquifer provides a water supply of about 120.000 m3d-1. The well-developed karst features in this hydrogeological system is responsible of the fast infiltration of rainfall in the saturated zone and, consequently, of the high discharge rate of Pertuso Spring (up to 3 m3/s). Thus, in the aim of emphasizing the presence of these karst features, due to which, there are limited attenuation processes in the unsaturated zone, in this work COP method has been applied by the implementation of a new discretization methodology of the hydrogeological basin using polygonal layer. Therefore, the hydrogeological catchment basin has been divided into 52 polygonal layer, representative of outcropping lithology and karst features, to which COP method has been applied. The intrinsic vulnerability maps, produced using a GIS approach, has been examinated and compared with the maps obtained using traditional vulnerability assessment method, which provides the discretization of the study area generating a grid map to which associate the Vulnerability Indexes. The results of this study highlight vulnerability from low to very high. The maximum vulnerability degree is due to karstic features responsible of high recharge and high hydraulic conductivity. The new proposed discretization of the hydrogeological basin using polygonal layer raise four vulnerability

  18. Autologous Bone Marrow Stromal Cell Transplantation for Central Nervous System Disorders – Recent Progress and Perspective for Clinical Application

    Directory of Open Access Journals (Sweden)

    Kuroda S

    2011-01-01

    Full Text Available There is increasing evidence that the transplanted BMSC significantly promote functional recovery after CNS damage in the animal models of various kinds of CNS disorders, including cerebral infarct, traumatic brain injury and spinal cord injury. However, there are several shortages of information when considering clinical application of BMSC transplantation for patients with CNS disorders. In this review, therefore, we discuss what we should clarify to establish cell transplantation therapy as the scientifically proven entity in clinical situation and describe our recent works for this purpose. The BMSC have the ability to alter their gene expression profile and phenotype in response to the surrounding circumstances and to protect the neurons by producing some neurotrophic factors. They also promote neurite extension and rebuild the neural circuits in the injured CNS. The BMSC can be expanded in vitro using the animal serum-free medium. Pharmacological modulation may accelerate the in vitro proliferation of the BMSC. Using in vivo optical imaging technique, the transplanted BMSC can non-invasively be tracked in the living animals for at least 8 weeks after transplantation. It is urgent issues to develop clinical imaging technique to track the transplanted cells in the CNS and evaluate the therapeutic significance of BMSC transplantation in order to establish it as a definite therapeutic strategy in clinical situation in the future.

  19. Development of a methodology for the economical analysis of fuel cycles, application to the Laguna Verde central

    International Nuclear Information System (INIS)

    In this work a methodology developed to carry out the economical analysis of the fuel cycle of a nuclear reactor is presented. The methodology was applied to the Laguna Verde Nuclear Power Station (CNLV). The design of the reload scenarios of the CNLV are made with the Core Master Presto code (CM-Presto), three-dimensional simulator of the reactor core, the launched data by this, as well as the information of the Energy use plan (PUE), it allowed us to obtain reliable results through the fitness of an algorithm of economic calculation that considers all the components of the fuel cycle to present worth. With the application of the methodology it was obtained the generated energy, as well as their respective cost of each sub lot type of assemblies by operation cycle, from the start-up of the CNLV until September 13, 2002. Using the present worth method its were moved all the values at November 5, 1988, date of operation beginning. To the final of the analysis an even cost of 6.188 mills/kWh was obtained for those first 9 cycles of the Unit 1 of the CNLV, being observed that the costs of those first 3 operation cycles are the more elevated. Considering only the values starting from the cycle 4, the levelled cost turns out to be of 5.96 mills/kWh. It was also obtained the cost by fuel lot to evaluate the performance of assemble with the same physical composition. (Author)

  20. Central Bank autonomy in Europe and Latin America: analysis of differences and applications Autonomía de la banca central en Europa y América Latina

    Directory of Open Access Journals (Sweden)

    Rollinat Robert

    1996-06-01

    Full Text Available This article makes a comparative analysis of the experiences of the independent central bank in Latin America and Europe. After reviewing the problems and theories of central bank autonomy, it studies the recent evolution of the Latin American central bank in comparison with the European central bank, high lights the perverse effects of the reforms, and shows that their objective is more the stability of the financial system than the stability of prices. Finally, it describes the tests to which the new Latin American central banks have been subjected and the effects on their credibility. It concludes that these entities have had to correct and pay for the incoherences and errors of the market, and that their independence or autonomy depends on their continuing to ful fill this role, not only for economíc or monetary reasons but for the needs of political and social democracy.Este artículo hace un análisis comparativo de las experiencias de la banca central independiente en América Latina y Europa. Después de revisar los problemas y las teorías de la autonompia de los bancos centrales, estudia la reciente evolución de la banca central latinoamericana en comparación con la europea, destaca los efectos perversos de estas reformas u muestra que sus objetivo es más la estabilidad del sistema financiero que la de los precios. Finalmente, describe las pruebas a que han sido sometidos los nuevos bancos centrales latinomaericanos y los efectos de sus credibilidad. Concluye que estas entidades han tenido que corregir y pagar las incoherencias y los errrores del mercado, y que su 'independencia' o autonomía depende de que sigan cumpliendo con ese papel no sólo por razones económicas o monetarias sino por las necesidades de la democracia política y social.

  1. Conversationalist Robot in student cafeteria

    OpenAIRE

    Trautman, Peter

    2012-01-01

    N.b.:In the wide upper panel, the position and trajectory marker (red lines and dots) are accurate according to the underlying grid. However, the projection of the video is offset slightly (due to camera curvature) from the tracks. This is an error in presentation; tracking error was almost uniformly within 1 foot of truth. A highly useful behavior of the robot was that it was always in motion. This was achieved safely by doing the following: if a collision was imminent, the forward vel...

  2. Yield and yield component of sweet potato as affected by Farmyard manure and Phosphorus application: in the case of Adami Tulu District, Central Rift Valley of Ethiopia

    Directory of Open Access Journals (Sweden)

    Teshome-Abdissa M

    2012-08-01

    Full Text Available Sweet potato is among the most important tuberous root crops produced in the central rift valley of Ethiopia. However, the yield and yield components obtained in the area is far below its genetic potential. The major cause of low yield is the use of poor agronomic practices. Specifically, scarcity of information on appropriate rates of fertilizers to be applied for growing the crop is one. Therefore, a field experiment was conducted to investigate the effect of farmyard manure and phosphorus on the yield and yield components of the crop at Adami Tulu, central rift valley of Ethiopia during the 2010 main cropping season. The treatments consisted of five levels of FYM (0, 5, 10, 15, 20 t ha-1 and three levels of P (0, 90,180 kg P2O5 ha-1. It was laid out as a Randomized Complete Block Design in a factorial arrangement, and replicated three times. A sweet potato cultivar known in the area Belela was used for the study. The result indicated that the main effect of FYM significantly (P < 0.05 affected; total tuberous root yield, tuberous root dry weight, fresh total biomass and dry harvest index. However, the main effect of P had no any significant influence on all parameters studied. Moreover, the interaction effects of FYM and P significantly (P < 0.05 affected; marketable root yield, specific gravity and total dry biomass yield. Combined application of 20 t farmyard manure ha-1 and 180 kg ha-1 P2O5 resulted in production of highest marketable yield (32.56 t ha-1. The lowest marketable yield (8.8 t ha-1 was obtained at the application of 0 t ha-1 FYM combined with 180 kg P2O5 ha-1. Thus, most of the yield and yield estimate parameters were enhanced in response to the application of FYM. For the two commonly used sweet potato quality parameters (dry matter and specific gravity, dry matter was not significantly responsive to both FYM and P while the highest specific gravity (1.09 was obtained at the combined application of 10 t FYM ha-1 and 0 kg P2O5

  3. Application of Planing Concept “Centralized and Unified” in Heavy Metal Pollution Control%“集中统一”在重金属污染治理规划中的运用

    Institute of Scientific and Technical Information of China (English)

    李水明

    2014-01-01

    The expected effect and significance for application of planing concept “Centralized and Unified” in heavy metal pollution control of Gejiu city .%阐述了“集中统一”规划理念在个旧市重金属污染治理规划中运用的预期效果及借鉴意义。

  4. Application of ice thermal storage central air-conditioning technology%冰蓄冷中央空调技术的应用

    Institute of Scientific and Technical Information of China (English)

    仝小鹏

    2011-01-01

    Integrating with the southwest airport refrigeration plant project,it introduces the actual application of ice thermal storage central air-conditioning technology,and respectively expounds the technological principle,structural composition and construction technology of ice thermal storage system.Through economic analysis,it summarizes the merits of ice thermal storage air-conditioning technology,and points out the prospects of the technology,which is worth promoting.%结合西北某机场制冷站工程,介绍了冰蓄冷中央空调技术的实际应用,分别阐述了冰蓄冷系统的工艺原理,结构组成及施工工艺,并通过经济性分析,总结了冰蓄冷中央空调技术的优点,指出该技术前景广阔,值得推广。

  5. Application of the Radionuclide Technique and other Methods for Assessing the Effectiveness of Soil Conservation Measures at the Novosil Study Site, Orel Region, Central Russia

    International Nuclear Information System (INIS)

    measured values is attributed to a high degree of soil degradation prior to the introduction of protective measures (reflected by the soil-morphological method) and lack of funding for maintaining the appropriate conditions of terraces and forest belts after collapse of the former Soviet Union (reflected by the 137Cs technique). Investigation undertaken in the study area confirmed that the radionuclide based technique is an efficient tool for quantitative evaluation of the effectiveness of soil conservation measures within the Central Russian Plain region. However further study is needed for improving the application of the radionuclide technique in the domain of sediment and pollutant transfer into the river system. (author)

  6. central t

    Directory of Open Access Journals (Sweden)

    Manuel R. Piña Monarrez

    2007-01-01

    Full Text Available Dado que la Regresión Ridge (RR, es una estimación sesgada que parte de la solución de la regresión de Mínimos Cuadrados (MC, es vital establecer las condiciones para las que la distribución central t de Student que se utiliza en la prueba de hipótesis en MC, sea también aplicable a la regresión RR. La prueba de este importante resultado se presenta en este artículo.

  7. 纳米技术在中枢神经系统中的作用%Application of nanotechnology in the central nervous system

    Institute of Scientific and Technical Information of China (English)

    刘啸白; 李冬阳; 刘丽波

    2011-01-01

    纳米技术是指在0.1-100nm量度范围内对物质结构和制造技术进行研究.纳米粒子能够进入细胞并与细胞及其组织发生作用,从而在分子水平上产生生物效应.由于纳米粒子可以和有机高分子多肽、无机盐等结合通过血脑屏障,已经在中枢神经系统药物转运、中枢神经系统疾病的诊断和治疗中发挥重要作用.本文从纳米粒子与血脑屏障的关系、纳米粒子在神经系统的保护、神经系统的再生中的作用等几方面阐述纳米技术在中枢神经系统应用中的现状与前景.%Nanotechnology refers to study of the structure of material and manufacturing technology, ranging from a few to about 100 nanometers.Nanoparticles can enter cells and interact with cells and their tissues, resulting in biological effects at the molecular level.As nanoparticles can combine with organic high polymer polypeptides, inorganic salt etc, and then across the blood-brain barrier(BBB), it has played the important role in the central nervous system (CNS) drug delivery, CNS diseases diagnosis and therapy.In this review, we would elaborate the research status and prospects of nanotechnology in CNS application from several aspects including the relationship between nanopartieles and BBB, the role of nanoparticles in the neuroprotection and neuroregeneration.

  8. Application of six sigma to reloads design of the Laguna Verde Central with length until 17 days; Aplicacion de seis sigma para disenar recargas de la Central Laguna Verde con duracion hasta de 17 dias

    Energy Technology Data Exchange (ETDEWEB)

    Espinosa G, J.M. [Comision Federal de Electricidad, Central Laguna Verde, Subgerencia General de Operacion, Planeacion, Veracruz (Mexico)]. e-mail: mespinos@cfe.gob.mx

    2007-07-01

    The more important value in the Laguna Verde Central it is the safety. The international experience it confirms us that the more safe plants its are those more productive, this conclusion and reasoning indicate to the power station that we are in the correct road, improving the acting we will obtain that greater interest for us in the Laguna Verde Central (to increase the safety) and as added value to be able to be one of the best business for the Federal Commission of Electricity. With a future vision and commitment of high acting was integrated in an external place to all the area headquarters: (Maintenance, Planning, Operation, Parts of Reserve, Finances, Contracts, Supplies, Warehouse, design Engineering, place Engineering, engineering of systems, radiological Protection, etc.) to carry out a combined work with the unique challenge of drifting with the biggest level detail the program of a recharge and certainly to get ready to achieve their execution (all this without omitting any consideration for smaller or simpler than it seemed), looking for high quality in the works, with and bigger level of safety, with the minimum possible dose, the more reasonable cost and considering a new concept of human character, to achieve the above-mentioned without the participant personnel's stress, with the premise that a good plan and commitment of all the only one that it can bring us as result it is the success of the whole organization. (Author)

  9. [Central anticholinergic syndrome].

    Science.gov (United States)

    Fernández Urretavizcaya, P; Cenoz Osinaga, J C; Jáuregui Garía, M L; Gállego Culleré, J

    1991-10-01

    Two new cases of anticolinergic central syndrome are described. The first case, a 8 year old girl, suffered a severe encefalopathy after topical application of mydriatic cholirio as an aid in a rutine study of ocular refraction. The second case, 67 year old man presented a severe neurological picture after accidental intake of a silvester plantground (Atropa belladonna). His neurological condition returned quickly to normal whith administration of physostigmine. Differents aspects of the etiology, clinical picture and diagnosis are discussed with special emphasis in patients with delirium or acute confusional states. Finally, attention is drawn in the necessity of a properly use of anticholinergic drugs overcoat in aged or children.

  10. Effects of farmers' practices of fertilizer application and land use types on subsequent maize yield and nutrient uptake in central Benin

    NARCIS (Netherlands)

    Saidou, A.; Kossou, D.; Acakpo, K.; Richards, P.; Kuyper, T.W.

    2012-01-01

    Four on-farm experiments in central Benin examined whether land-use succession and fertilizer treatments for prior cotton would sustain subsequent maize crop yields and achieve balanced plant nutrition. Treatments consisted of three prior land use successions, i.e. before planting maize (egusi melon

  11. Application of chromium stable isotopes to the evaluation of Cr(VI) contamination in groundwater and rock leachates from central Euboea and the Assopos basin (Greece)

    DEFF Research Database (Denmark)

    Economou-Eliopoulos, Maria; Frei, Robert; Atsarou, Cathy

    2014-01-01

    Major and trace elements (a) in groundwater, ultramafic rocks from natural outcrops and soil samples from cultivated sites of Central Euboea and Assopos basin, and (b) in experimentally produced laboratory water leachates of rocks and soils were investigated by SEM/EDS, XRD and ICP/MS. In additio...

  12. Application of the Central Limit Theorem in microbial risk assessment: High number of serving reduces the Coefficient of Variation of food-borne burden-of-illness

    NARCIS (Netherlands)

    Pérez-Rodríguez, F.; Zwietering, M.H.

    2012-01-01

    The Central Limit Theorem (CLT) is proposed as a means of understanding microbial risk in foods from a Public Health perspective. One variant of the CLT states that as the number of random variables, each with a finite mean and variance, increases (¿8), the distribution of the sum (or mean) of those

  13. Detection of Ca2+-dependent acid phosphatase activity identifies neuronal integrity in damaged rat central nervous system after application of bacterial melanin

    Directory of Open Access Journals (Sweden)

    Tigran R Petrosyan

    2016-01-01

    Full Text Available The study aims to confirm the neuroregenerative effects of bacterial melanin (BM on central nervous system injury using a special staining method based on the detection of Ca2+-dependent acid phosphatase activity. Twenty-four rats were randomly assigned to undergo either unilateral destruction of sensorimotor cortex (group I; n = 12 or unilateral rubrospinal tract transection at the cervical level (C3–4 (group II; n = 12. In each group, six rats were randomly selected after surgery to undergo intramuscular injection of BM solution (BM subgroup and the remaining six rats were intramuscularly injected with saline (saline subgroup. Neurological testing confirmed that BM accelerated the recovery of motor function in rats from both BM and saline subgroups. Two months after surgery, Ca2+-dependent acid phosphatase activity detection in combination with Chilingarian's calcium adenoside triphosphate method revealed that BM stimulated the sprouting of fibers and dilated the capillaries in the brain and spinal cord. These results suggest that BM can promote the recovery of motor function of rats with central nervous system injury; and detection of Ca2+-dependent acid phosphatase activity is a fast and easy method used to study the regeneration-promoting effects of BM on the injured central nervous system.

  14. Detection of Ca2+-dependent acid phosphatase activity identiifes neuronal integrity in damaged rat central nervous system after application of bacterial melanin

    Institute of Scientific and Technical Information of China (English)

    Tigran R Petrosyan; Anna S Ter-Markosyan; Anna S Hovsepyan

    2016-01-01

    The study aims to confirm the neuroregenerative effects of bacterial melanin (BM) on central nervous system injury using a special staining method based on the detection of Ca2+-dependent acid phosphatase activity. Twenty-four rats were randomly assigned to undergo either unilateral destruction of sensorimotor cortex (group I;n=12) or unilateral rubrospinal tract transection at the cervical level (C3–4) (group II;n=12). In each group, six rats were randomly selected after surgery to undergo intramuscular injection of BM solution (BM subgroup) and the remaining six rats were intramuscularly injected with saline (saline subgroup). Neurological testing confirmed that BM accelerated the recovery of motor function in rats from both BM and saline subgroups. Two months after surgery, Ca2+-dependent acid phosphatase activity detection in combination with Chilingarian’s calcium adenoside triphosphate method revealed that BM stimulated the sprouting of ifbers and dilated the capillaries in the brain and spinal cord. These results sug-gest that BM can promote the recovery of motor function of rats with central nervous system injury;and detection of Ca2+-dependent acid phosphatase activity is a fast and easy method used to study the regenera-tion-promoting effects of BM on the injured central nervous system.

  15. Detection of Ca(2+)-dependent acid phosphatase activity identifies neuronal integrity in damaged rat central nervous system after application of bacterial melanin.

    Science.gov (United States)

    Petrosyan, Tigran R; Ter-Markosyan, Anna S; Hovsepyan, Anna S

    2016-07-01

    The study aims to confirm the neuroregenerative effects of bacterial melanin (BM) on central nervous system injury using a special staining method based on the detection of Ca(2+)-dependent acid phosphatase activity. Twenty-four rats were randomly assigned to undergo either unilateral destruction of sensorimotor cortex (group I; n = 12) or unilateral rubrospinal tract transection at the cervical level (C3-4) (group II; n = 12). In each group, six rats were randomly selected after surgery to undergo intramuscular injection of BM solution (BM subgroup) and the remaining six rats were intramuscularly injected with saline (saline subgroup). Neurological testing confirmed that BM accelerated the recovery of motor function in rats from both BM and saline subgroups. Two months after surgery, Ca(2+)-dependent acid phosphatase activity detection in combination with Chilingarian's calcium adenoside triphosphate method revealed that BM stimulated the sprouting of fibers and dilated the capillaries in the brain and spinal cord. These results suggest that BM can promote the recovery of motor function of rats with central nervous system injury; and detection of Ca(2+)-dependent acid phosphatase activity is a fast and easy method used to study the regeneration-promoting effects of BM on the injured central nervous system. PMID:27630700

  16. Central Pain Syndrome

    Science.gov (United States)

    ... Enhancing Diversity Find People About NINDS NINDS Central Pain Syndrome Information Page Table of Contents (click to ... being done? Clinical Trials Organizations What is Central Pain Syndrome? Central pain syndrome is a neurological condition ...

  17. Central venous line - infants

    Science.gov (United States)

    CVL - infants; Central catheter - infants - surgically placed ... plastic tube that is put into a large vein in the chest. WHY IS A ... central catheter (PICC) or midline central catheter (MCC). A CVL ...

  18. Development of a methodology for the economical analysis of fuel cycles, application to the Laguna Verde central; Desarrollo de una metodologia para el analisis economico de ciclos de combustible, aplicacion a la Central Laguna Verde

    Energy Technology Data Exchange (ETDEWEB)

    Malfavon, S.M.; Trejo, M.G.; Hernandez, H. [FI-UNAM, 04500 Mexico D.F. (Mexico); Francois, J.L.; Ortega, R.F. [FI-UNAM, Paseo Cuauhnahuac 8532, Jiutepec, Morelos (Mexico)

    2003-07-01

    In this work a methodology developed to carry out the economical analysis of the fuel cycle of a nuclear reactor is presented. The methodology was applied to the Laguna Verde Nuclear Power Station (CNLV). The design of the reload scenarios of the CNLV are made with the Core Master Presto code (CM-Presto), three-dimensional simulator of the reactor core, the launched data by this, as well as the information of the Energy use plan (PUE), it allowed us to obtain reliable results through the fitness of an algorithm of economic calculation that considers all the components of the fuel cycle to present worth. With the application of the methodology it was obtained the generated energy, as well as their respective cost of each sub lot type of assemblies by operation cycle, from the start-up of the CNLV until September 13, 2002. Using the present worth method its were moved all the values at November 5, 1988, date of operation beginning. To the final of the analysis an even cost of 6.188 mills/kWh was obtained for those first 9 cycles of the Unit 1 of the CNLV, being observed that the costs of those first 3 operation cycles are the more elevated. Considering only the values starting from the cycle 4, the levelled cost turns out to be of 5.96 mills/kWh. It was also obtained the cost by fuel lot to evaluate the performance of assemble with the same physical composition. (Author)

  19. 大数定律及中心极限定理在保险中的应用%Applications of Law of Large Numbers and Central Limit Theorem in Insurance

    Institute of Scientific and Technical Information of China (English)

    王丙参; 魏艳华; 林朱

    2011-01-01

    文中研究了大数定律及中心极限定理的含义及关系,阐述了它们在制定保费及自留额、拟定保险单位数及减少保险个人平均危险值等方面的应用.%It discussed the meanings and relationships of the law of large numbers and Central Limit Theorem, stud- ied the applications in the formulating premium and retention, the insurance units, reducing the average individual risk values, etc.

  20. The role of central, regional and local administrations in the application of the Kyoto protocol in the forestry sector in Italy

    Directory of Open Access Journals (Sweden)

    Pompei E

    2007-01-01

    Full Text Available According to art. 3.3 and 3.4 of the Kyoto Protocol and subsequent UNFCCC COP's and national decisions, Italy shall report the net changes in GHG emissions by sources and removals by sinks resulting from afforestation, reforestation and deforestation (art. 3.3 and forest management (art. 3.4 activities. To assess art. 3.3 activities, Italy will define methods to estimate land use changes occurring after 31 December 1989. The paper considers the key-role that central administration shall have, as well as the role of regional and local administrations in order to solve some specific topics regarding data collection and management issues.

  1. Central Puget Sound Ecopath/Ecosim model biological parameters - Developing food web models for ecosystem-based management applications in Puget Sound

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This project is developing food web models for ecosystem-based management applications in Puget Sound. It is primarily being done by NMFS FTEs and contractors, in...

  2. Application of PLC Centralized Control System of Coal Mine Belt Conveyor%PLC集中控制系统在煤矿胶带输送机上的应用

    Institute of Scientific and Technical Information of China (English)

    秦永康; 黄和平

    2011-01-01

    针对某矿胶带运输系统线路长、岗位多、联络环节多的特点,提出了一种采用PLC集中控制系统控制煤矿胶带输送机的方案,介绍了PLC集中控制系统的构成、工作原理和系统功能.该系统通过集中控制和工业电视相结合,对井下主煤流强力胶带输送机和振动给煤机及煤仓煤位计等相关设施进行监测,实现了主煤流系统的集中控制.实际应用表明,该系统运行良好,实现了胶带输送机的安全高效运行.%In view of characteristics of long lines, multi posts and multi links of transport system of belt converyor of a mine, the paper proposed a scheme which adopts PLC centralized control system to control coal mine belt conveyor.It introduced composition, working principle and functions of PLC centralized control system.The system combines industrial television with centralized control to monitor related devices such as underground powerful belt conveyor, vibration coal feeder and coal level sensor of coal bunker, which realizes centralized control of main coal flow system.The practical application showed that the system runs well, and achieves safe and efficient running of conveyor belt.

  3. To centralize or not to centralize?

    OpenAIRE

    Campbell, Andrew; Kunisch, Sven; Müller-Stewens, Günter

    2011-01-01

    The CEO's dilemma-were the gains of centralization worth the pain it could cause?-is a perennial one. Business leaders dating back at least to Alfred Sloan, who laid out GM's influential philosophy of decentralization in a series of memos during the 1920s, have recognized that badly judged centralization can stifle initiative, constrain the ability to tailor products and services locally, and burden business divisions with high costs and poor service.1 Insufficient centralization can deny bus...

  4. Application of ERP system in material management in central sterilization supply department%ERP系统在消毒供应中心物资管理中的应用

    Institute of Scientific and Technical Information of China (English)

    邱素红; 陈严伟; 高玉华

    2012-01-01

    OBJECTIVE To use enterprise resource planning (ERP) system for the management of medical consumables in central sterilization supply department. METHODS Standardized process of medical consumables was established. ERP system was adopted for the management of the purchasing application, storage, outbound, and inventory of the medical consumables in central sterilization supply department. RESULTS The application of ERP system has improved the management of medical consumables, raising work efficiency, reduced the loopholes and waste and saved the cost. CONCLUSION Central sterilization supply department has achieved a computerized networking, transparent, and precise management after the use of ERP system.%目的 消毒供中心应用企业资源计划系统(ERP)进行医用耗材管理.方法 采用建立医用耗材的标准化、规范化流程,ERP系统对消毒供应中心医用耗材的采购申请、入库、出库、库存等进行管理.结果 应用ERP系统完善了消毒供应中心对医用耗材的管理方法,提高了工作效率,减少了临床使用过程中的漏洞和浪费,节约了成本.结论 应用耗材ERP系统后,使消毒供应中心达到计算机网络化、透明化、精确化管理.

  5. Hope for Central China

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    The cities surrounding Changsha and Wuhan in the middle reaches of the Yangtze River will ally to form a new pilot zone to boost regional economic development China’s fourth pilot zone for compre- hensive and coordinated economic reform will soon debut in the middle reaches of the Yangtze River,open- ing a new area to attract foreign investment. The application has been submitted to the State Council for approval. The pilot zone will include two clusters of cities in central China:One consists of Wuhan,capital of Hubei Province,and eight surrounding cities in Hubei,and the other is composed of Changsha,Zhuzhou and Xiangtan,three major cities in Hunan Province.

  6. Initial TMX central-cell ICRH experiments

    International Nuclear Information System (INIS)

    Four topics are discussed in this report: the feasibility of applying ion cyclotron resonance heating (ICRH) in the TMX central cell, some applications of heating, the results of preliminary experiments, and plans for further ICRH experiments

  7. Application of ultrasound differential diagnosis in abnormalities of fetus central nerve system%超声鉴别诊断技术在胎儿中枢神经系统畸形诊断中的应用

    Institute of Scientific and Technical Information of China (English)

    邓学东; 李红; 梁青; 常红梅; 姜小力; 唐亚奇; 梁泓; 冯鸿; 陆伟

    2011-01-01

    Objective To improve the clinical application of ultrasound differential diagnosis in abnormalities of fetus central nerve system. Methods Ultrasound imaging features in 217 cases of abnormalities in central nerve system confirmed by autopsy or follow-up were analyzed retrospectively. Results A total of 217 cases of anomaly in the central never system were examined prenatally by ultrasound and each showed typical imaging feature. Among these cases , there were 45 cases of anencephaly, 4 cases of hydranencephaly, 5 cases of arachnoid' s cyst, 2 cases of aneurysm of the vein of Galen, 78 cases of ventriculomegaly ( among them 46 cases of aqueduct stenosis), 13 cases of cephalocele, 17 cases of Dandy-Walker complex, 23 cases of spina bifida, 9 cases of holoprosencephaly, 5 cases of agenesis of the corpus callosum,8 cases of sacrococcygeal teratoma and 8 cases of choroid plexus cysts.Conclusion Application of ultrasound differential diagnosis by ultrasound for detection of abnormalities in fetus central nerve system( i. e. three sections and 12clues ), is extremely important.%目的 探讨产前超声鉴别诊断技术在胎儿中枢神经系统畸形诊断中的应用.方法 对经随访或引产证实217例中枢神经系统畸形的声像图特征进行回顾性分析.结果 产前超声诊断217例胎儿中枢神经系统畸形,其中无脑儿45例、水脑畸形4例、蛛网膜囊肿5例、Galen静脉瘤2例、脑室扩张78例(其中46例是中脑导水管狭窄)、脑膨出13例、Dandy-Walker综合征17例、开放性脊柱裂23例、前脑无裂畸形9例、胼胝体缺失5例、骶尾部畸胎瘤8例、脉络丛囊肿8例.结论 掌握超声检查胎儿中枢神经系统畸形的鉴别诊断技术,即三个切面和12种分析思路,对产前超声检查极为重要.

  8. Constructing disease-specific gene networks using pair-wise relevance metric: Application to colon cancer identifies interleukin 8, desmin and enolase 1 as the central elements

    Directory of Open Access Journals (Sweden)

    Jiang Wei

    2008-08-01

    Full Text Available Abstract Background With the advance of large-scale omics technologies, it is now feasible to reversely engineer the underlying genetic networks that describe the complex interplays of molecular elements that lead to complex diseases. Current networking approaches are mainly focusing on building genetic networks at large without probing the interaction mechanisms specific to a physiological or disease condition. The aim of this study was thus to develop such a novel networking approach based on the relevance concept, which is ideal to reveal integrative effects of multiple genes in the underlying genetic circuit for complex diseases. Results The approach started with identification of multiple disease pathways, called a gene forest, in which the genes extracted from the decision forest constructed by supervised learning of the genome-wide transcriptional profiles for patients and normal samples. Based on the newly identified disease mechanisms, a novel pair-wise relevance metric, adjusted frequency value, was used to define the degree of genetic relationship between two molecular determinants. We applied the proposed method to analyze a publicly available microarray dataset for colon cancer. The results demonstrated that the colon cancer-specific gene network captured the most important genetic interactions in several cellular processes, such as proliferation, apoptosis, differentiation, mitogenesis and immunity, which are known to be pivotal for tumourigenesis. Further analysis of the topological architecture of the network identified three known hub cancer genes [interleukin 8 (IL8 (p ≈ 0, desmin (DES (p = 2.71 × 10-6 and enolase 1 (ENO1 (p = 4.19 × 10-5], while two novel hub genes [RNA binding motif protein 9 (RBM9 (p = 1.50 × 10-4 and ribosomal protein L30 (RPL30 (p = 1.50 × 10-4] may define new central elements in the gene network specific to colon cancer. Gene Ontology (GO based analysis of the colon cancer-specific gene network and

  9. Deconstruction of the asbestos cement roof of the central market in Alicante difficulties in the practical application of RD 396/2006 (works with risk of exposure to asbestos); Deconstruccion de la cubierta de asbesto-cemento del Mercado Central de Abastos de Alicante. Dificultades en la aplicacion practica del RD 396/2006 (trabajos con riesgo de exposicion al amianto)

    Energy Technology Data Exchange (ETDEWEB)

    Sirvent Perez, C. D.

    2010-07-01

    The project and the works described below mainly deal with the deconstruction of the current asbestos-cement roof of the Central Market in Alicante in order to replace it with another roof of zinc diamond scales, similar to the original which was implementation in 1921 when the building went into service. These works were necessary to avoid the causes (and consequences) that generate the appearance of rainwater infiltration, as was described in an earlier report that was done in 2006, also drafted by the undersigned technicians. The article shows the difficulty of the practical application of RD 396/2006 (minimum health and safety requirements for works with risks of exposure to asbestos) in a case of a certain complexity such as this, especially in areas such as economic (rising costs), technical (increasing difficulty of implementation), and the total duration of the work (total time extension due to interference with other trades). (Author) 14 refs.

  10. Application of fractal modeling and PCA method for hydrothermal alteration mapping in the Saveh area (Central Iran based on ASTER multispectral data

    Directory of Open Access Journals (Sweden)

    Mirko Ahmadfaraj

    2016-06-01

    Full Text Available The aim of this study is determination and separation of alteration zones using Concentration-Area (C-A fractal model based on remote sensing data which has been extracted from Advanced Spaceborne Thermal Emission and Reflection Radiometer (ASTER images. The studied area is on the SW part of Saveh, 1:250,000 geological map, which is located in Urumieh-Dokhtar magmatic belt, Central Iran. The pixel values were computed by Principal Component Analysis (PCA method used to determine phyllic, argillic, and propylitic alteration zones. The C-A fractal model is utilized for separation of different parts of alteration zones due to their intensity. The log-log C-A plots reveal multifractal nature for phyllic, argillic, and propylitic alteration zones. The obtained results based on fractal model show that the main trend of the alteration zones is in NW-SE direction. Compared to the geological map of the study area and copper mineralizations, the alteration zones have been detected properly and correlate with the mineral occurrences, intrusive rock, and faults.

  11. The application of terrestrial laser scanner and photogrammetry in measuring erosion and deposition processes in humid badlands in the Central Spanish Pyrenees

    Science.gov (United States)

    Nadal-Romero, E.; Revuelto, J.; Errea, P.; López-Moreno, J. I.

    2015-04-01

    Erosion and deposition processes in badland areas are usually estimated using traditional observations of topographic changes, measured by erosion pins or profile meters (invasive techniques). In recent times, geomatic techniques (non-invasive) have been routinely applied in geomorphology studies, especially in erosion studies. These techniques provide the opportunity to build high-resolution topographic models at subcentimeter accuracy. By comparing different 3-D point clouds of the same area, obtained at different time intervals, the variations in the terrain and temporal dynamics can be analyzed. The aim of this study is to assess and compare the functioning of Terrestrial Laser Scanner (TLS, RIEGL LPM-321) and close range photogrammetry techniques (Camera FUJIFILM, Finepix x100 and Software PhotoScan by AgiSoft), to evaluate erosion and deposition processes in a humid badland area in the Central Spanish Pyrenees. Results show that TLS data sets and photogrammetry techniques provide new opportunities in geomorphological erosion studies. The data we recorded over one year demonstrated that north-facing slopes experienced more intense and faster changing geomorphological dynamics than south-facing slopes as well as the highest erosion rates. Different seasonal processes were observed, with the highest topographic differences observed during winter periods and the high intensity rainfalls in summer. While TLS provided the highest resolution models, photogrammetry was still a faster methodology in the field and precise at short distances. Both techniques do not require direct contact with the soil and thus prevent the usual surface disturbance of traditional and invasive methods.

  12. Development and application of a fecal antigen diagnostic sandwich ELISA for estimating prevalence of Fasciola gigantica in cattle in central Java, Indonesia.

    Science.gov (United States)

    Estuningsih, Endah; Spithill, Terry; Raadsma, Herman; Law, Ruby; Adiwinata, G; Meeusen, Els; Piedrafita, David

    2009-04-01

    The purpose of this study was to compare the sensitivity and specificity of an ELISA test to detect Fasciola gigantica antigens (coproantigens) in bovine feces, with fecal egg counting and an ELISA for detecting anti-F. gigantica antibodies in serum. Monoclonal antibodies to cathepsin L were generated and used to capture this antigen in feces of infected cattle. Blood, feces, and livers were collected from 150 cattle at an abattoir in Jakarta, Indonesia, for anti-Fasciola antibodies, coproantigen detection, and F. gigantica egg and worm counts. Fluke recovery varied from 1 to 426 per host, with a mean of 32 flukes. The results showed that the sensitivity and specificity of coproantigen detecting ELISA (95 and 91%, respectively) was better than the anti-F. gigantica antibody ELISA (91 and 88%, respectively) and to fecal egg counting (87 and 100%, respectively). The coproantigen ELISA was able to detect 100% of the cattle with >15 flukes. A survey of 305 cattle in central Java over a 10-mo period validated this test in the field, demonstrating a high prevalence of fascioliasis and establishing the test as a useful diagnostic method to determine patent F. gigantica infections in cattle.

  13. Application of the Central Limit Theorem in microbial risk assessment: high number of servings reduces the Coefficient of Variation of food-borne burden-of-illness.

    Science.gov (United States)

    Pérez-Rodríguez, Fernando; Zwietering, Marcel H

    2012-02-15

    The Central Limit Theorem (CLT) is proposed as a means of understanding microbial risk in foods from a Public Health perspective. One variant of the CLT states that as the number of random variables, each with a finite mean and variance, increases (→∞), the distribution of the sum (or mean) of those variables approximates a normal distribution. On the basis of the CLT, the hypothesis introduced by this paper states that the Coefficient of Variation (CV) of the annual number of food-borne illness cases decreases as a result of a larger number of exposures (or servings) (n). Second-order Monte-Carlo analysis and classical statistics were used to support the hypothesis, based on existing risk models on Listeria monocytogenes in deli meat products focused on elderly people in the United States. Likewise, the hypothesis was tested on epidemiological data of annual incidence of salmonellosis and listeriosis in different countries (i.e. different n). Although different sources of error affected the accuracy of the results, both the Monte-Carlo analysis (in silico) and epidemiological data (in vivo), especially for salmonellosis, demonstrated that the CV of the annual number of cases decreased as n increased as stated by the CLT. Furthermore, results from this work showed that classical statistical methods can be helpful to provide reliable risk estimates based on simple and well-established statistical principles.

  14. Coverage centralities for temporal networks*

    Science.gov (United States)

    Takaguchi, Taro; Yano, Yosuke; Yoshida, Yuichi

    2016-02-01

    Structure of real networked systems, such as social relationship, can be modeled as temporal networks in which each edge appears only at the prescribed time. Understanding the structure of temporal networks requires quantifying the importance of a temporal vertex, which is a pair of vertex index and time. In this paper, we define two centrality measures of a temporal vertex based on the fastest temporal paths which use the temporal vertex. The definition is free from parameters and robust against the change in time scale on which we focus. In addition, we can efficiently compute these centrality values for all temporal vertices. Using the two centrality measures, we reveal that distributions of these centrality values of real-world temporal networks are heterogeneous. For various datasets, we also demonstrate that a majority of the highly central temporal vertices are located within a narrow time window around a particular time. In other words, there is a bottleneck time at which most information sent in the temporal network passes through a small number of temporal vertices, which suggests an important role of these temporal vertices in spreading phenomena. Contribution to the Topical Issue "Temporal Network Theory and Applications", edited by Petter Holme.Supplementary material in the form of one pdf file available from the Journal web page at http://dx.doi.org/10.1140/epjb/e2016-60498-7

  15. Central station market development strategies for photovoltaics

    Science.gov (United States)

    1980-01-01

    Federal market development strategies designed to accelerate the market penetration of central station applications of photovoltaic energy system are analyzed. Since no specific goals were set for the commercialization of central station applications, strategic principles are explored which, when coupled with specific objectives for central stations, can produce a market development implementation plan. The study includes (1) background information on the National Photovoltaic Program, photovoltaic technology, and central stations; (2) a brief market assessment; (3) a discussion of the viewpoints of the electric utility industry with respect to solar energy; (4) a discussion of commercialization issues; and (5) strategy principles. It is recommended that a set of specific goals and objectives be defined for the photovoltaic central station program, and that these goals and objectives evolve into an implementation plan that identifies the appropriate federal role.

  16. Central station market development strategies for photovoltaics

    Science.gov (United States)

    1980-11-01

    Federal market development strategies designed to accelerate the market penetration of central station applications of photovoltaic energy system are analyzed. Since no specific goals were set for the commercialization of central station applications, strategic principles are explored which, when coupled with specific objectives for central stations, can produce a market development implementation plan. The study includes (1) background information on the National Photovoltaic Program, photovoltaic technology, and central stations; (2) a brief market assessment; (3) a discussion of the viewpoints of the electric utility industry with respect to solar energy; (4) a discussion of commercialization issues; and (5) strategy principles. It is recommended that a set of specific goals and objectives be defined for the photovoltaic central station program, and that these goals and objectives evolve into an implementation plan that identifies the appropriate federal role.

  17. Application of central air conditioner system on modular drilling rig of offshore ifxed platform%集中空调系统在海洋固定平台模块钻机上的应用研究

    Institute of Scientific and Technical Information of China (English)

    罗立臣; 许瑞杰; 马冬辉

    2014-01-01

    Based on the air conditioner selection of Lu Feng7-2 oil ifeld modular drilling rig project, this paper determines two sets of selection of air conditioner by preliminary study, which are central and separation air conditioner systems, respectively. With comparison between the central air conditioner and the split air conditioner in cost, effciency, comfort, space, etc., it concludes that the central air conditioner system has the advantages of lower operation cost, higher energy effciency ratio, better comfort capability, smaller space occupation and so on. It also analyzes its superiority and prospect of application on the modular drilling rig of offshore ifxed platform, which can provide a certain reference for the room cooling design and the equipment selection.%结合陆丰7-2油田模块钻机项目空调选型,通过前期调查研究制定了两套空调选型方案:集中空调系统方案和分体空调系统方案。通过对比两者在费用、工作效率、舒适性、占用空间等方面的特点,得出集中空调系统具有初始投入及运行成本低、能效比高、舒适性好、占地面积小等方面的优点,并分析了集中空调在海洋固定平台模块钻机上使用的优越性以及应用前景,对海洋固定平台模块钻机的房间制冷设计及设备选型提供了一定的参考。

  18. 国库集中支付制度在高等院校实行的问题和建议%The Application of Centralized Treasury Payment System (CTPS) in Universities and Colleges

    Institute of Scientific and Technical Information of China (English)

    张弛

    2011-01-01

    2010年9月26日,财政部下发了财库[2010]104号《中央单位教育收费收缴管理暂行办法》的通知通知中对教育收费收缴工作作了具体要求。国库集中支付是目前财政管理制度改革的一项重要内容,在高校实施国库集中支付制度,对高校的预算管理、财务管理、会计核算产生了深刻的影响。文章将国库集中支付制度与通知相结合论述了这项制度在高校具体实施过程中所引发的问题,并对此提出意见和建议。%In September 26, 2010, Ministry of Finance issued the Notification of 2010 No.104 Provision, Administration of Educational Tuition Fees Collection for Central Government Organizations. It regulates the collection of education fees in central government organizations. Centralized Treasury Payment System (CTPS) is one of the important aspects in the reform of China's finance administration system. The application of CTPS in universities and colleges will exert a widespread and profound influ- ence on budgeting, finance and accounting management. This paper discusses the requirements of the 104 Provision, analyzes the problems and possible solutions with respect to the implementation of CTPS.

  19. NIDDK Central Repository

    Data.gov (United States)

    U.S. Department of Health & Human Services — The NIDDK Central Repository stores biosamples, genetic and other data collected in designated NIDDK-funded clinical studies. The purpose of the NIDDK Central...

  20. 集中式制播一体网架构及应用%A Perception on TV Centralized Network System of Producing and Broadcasting, and Its Application

    Institute of Scientific and Technical Information of China (English)

    陈泽华; 王海峰

    2012-01-01

    With the digitalization, high definition,integration and networking of broadcast television and the rap- new media development, through the building of digitalized and networked broadcast system to realize the pro- duction line for programming, broadcasting and storage administration, in order to further optimize work process, improve productivity and administration standard, it put forward higher request for programming and safe broad- casting and reliability of television station. To construct a centralized whole - station network including program- ming, broadcasting, recording, filing and backup, could satisfy the requirement in programming operation and solve security problem in system interconnection among whole station network, support and integrate digital broadcasting, website, outdoor media and other new media, realize net publishment of media resource, broad- cast programs webcast and some new operation, so that to widen the channel of income for station.%构建一个集节目制作、播出、收录、归档及备份于一体的集中式全台网,既满足节目制作的业务需求,又很好地解决全台网建设中关于系统互联互通的安全问题,实现对数据广播、网站、户外媒体等新媒体的支持和整合功能,实现媒资素材的网络发布、广播电视节目的网络直播等新业务开发,拓宽创收渠道。主要介绍集中式制播一体网的技术架构、系统组成、关键设备选型及安全设计与应用。

  1. Applications of seismic pattern recognition and gravity inversion techniques to obtain enhanced subsurface images of the Earth's crust under the Central Metasedimentary Belt, Grenville Province, Ontario

    Science.gov (United States)

    Roy, Baishali; Mereu, R. F.

    2000-12-01

    Project Lithoprobe's Abitibi-Grenville transect seismic reflection lines 32 and 33 traverse the exposed Central Metasedimentary Belt (CMB) located in the Grenville province of the Precambrian Shield of Canada in southern Ontario. These seismic lines image a zone with a protracted deformational history spanning more than 300Myr. Detailed examination of the commercially processed stacked sections reveals a number of significant deficiencies in some important areas. The image quality in these zones of reduced coherency needs to be enhanced to examine specific features and their relation to the surface geology. Examination of near-vertical seismic data from Lines 32 and 33 revealed that the signal-to-noise ratio was not improved by stacking, due to misalignment of signals even after static, normal moveout corrections and residual static corrections. The presumed reason is that reflected seismic energy following long ray paths in heterogeneous media suffers from relative advances and delays in its propagation, and hence arrives at slightly different times at the receivers, tending to be poorly aligned relative to its theoretical traveltime curves. A pattern recognition (PR) method for signal enhancement followed by energy stacking in moving time windows was used in this study to improve the images in spite of misalignments. Reprocessing has refined the geometry of the reflection profiles. The objective of this paper is to use enhanced images of the seismic reflection data obtained by using a PR approach together with gravity data, using 2.5-D forward and 3-D inversion routines, to give an improved model of subsurface structure in the vicinity of lines 32 and 33. Line 32 is dominated by southeast-dipping reflectors soling into the lower crust. The listric geometry of the strong reflection packages of the CMB boundary thrust zone is interpreted to represent a crustal-scale ramp-flat geometry that accommodated northwest-directed tectonic transport of the CMB. This

  2. 自适应模糊PID控制策略在中央空调系统中的应用研究%Application of of Self-adaptive Fuzzy PID Controllng Strategy to Central Air-conditioning System

    Institute of Scientific and Technical Information of China (English)

    许立

    2012-01-01

    The control process of the central air-conditioning system is complicated.By combining traditional PID control and fuzzy control,this paper introduces a designing method for self-adaptive fuzzy PID control and its application to controlling the central air-conditioning system.The experiments of the simulation model show that the self-adaptive fuzzy PID control makes up for the shortcomings of the fuzzy control and PID control,and has advantages of flexible control,high precision,rapid adjustment,small overshoot,good robustness and stability.So it is feasible.%中央空调系统的控制过程非常复杂,将传统的PID控制和模糊控制相结合,提出了一种自适应模糊PID控制的设计方法,并将其应用于中央空调系统的实际控制中.通过仿真模型的实验表明,自适应模糊PID控制弥补了模糊控制和PID控制的缺点,具有控制灵活,精度高,调节迅速,超调量小的优点,鲁棒性和稳定性好,具有一定的可行性.

  3. 水力平衡调试在中央空调中节能的应用%On application of hydraulic balancing adjustment in energy-saving of central air-conditioner

    Institute of Scientific and Technical Information of China (English)

    田雷

    2012-01-01

    Based on the importance of the hydraulic balancing in the heating air-conditioning system, the paper indicates the application of the hydraulic balancing adjustment in energy-saving of central air-conditioner from the concept of the hydraulic balancing, the adjustment principle and the practical cases, so as to realize the hydraulic balance in the operation process of the central air-constioner and achieve the energy-saving.%鉴于水力平衡在暖通空调系统中的重要作用,从水力平衡的概念、调节原理以及实际应用案例等方面入手,对水力平衡调试在中央空调中节能的应用进行简单论述,以实现中央空调运行过程的水力平衡,达到节能的目的。

  4. Central and peripheral demyelination

    OpenAIRE

    Man Mohan Mehndiratta; Natasha Singh Gulati

    2014-01-01

    Several conditions cause damage to the inherently normal myelin of central nervous system, perepheral nervous system or both central and perepheral nervous system and hence termed as central demyelinating diseases, perepheral demyelinating diseases and combined central and perepheral demyelinating diseases respectively. Here we analysed and foccused on the etiology, prevalance, incidence and age of these demyelinating disorders. Clinical attention and various diagnostic tests are needed to ad...

  5. 中央轮胎充放气系统及在轮式车辆上的应用%The Application of Central Tyre Inflation Systemon Wheeled Vehicle

    Institute of Scientific and Technical Information of China (English)

    张占理

    2001-01-01

    The central tyre inflation system (CTIS). has an important influence on improving cross -country capability of the wheeled vehicle. Some test data are given in this paper. This paper introduces application of some CTIS on the wheeled vehicle. CTIS93 is compared with other CTIS in performence and structure.%中央轮胎充放气系统又称CTIS系统,它对提高轮式车辆的越野能力有重大影响。该文给出了一些试验数据,介绍了几种CTIS系统在车上的应用,并就国产CTIS93系统同其它系统在性能和结构上进行了比较。

  6. Applications of the monitor of loose parts in the cycle 6 of the Laguna Verde Unit 2 power plant; Aplicaciones del monitor de partes sueltas en el ciclo 6 de la Unidad 2 de la central Laguna Verde

    Energy Technology Data Exchange (ETDEWEB)

    Calleros, G.; Mendez, A.; Gomez, R.A. [Comision Federal de Electricidad, Central Nucleoelectrica Laguna Verde, Veracruz (Mexico); Castillo, R.; Bravo, J.M. [ININ, A.P. 18-1027, 11801 Mexico D.F. (Mexico)]. E-mail: gcm9acpp@cfe.gob.mx

    2004-07-01

    The monitor of loose parts (Loose Parts Monitoring System) installed in the Unit 2 of the Laguna Verde Central is a tool to detect strange objects or parts loose in the system of refrigeration of the reactor that could be impacted in the walls of the recirculation knots or in the internal of the reactor. In this work two applications are shown carried out with the Monitor of Loose Parts, determining the characteristics of the stable nominal conditions, those which when changing, they are used to diagnose during the Cycle 6 of the Unit 2, failures in the components of the the recirculation circuits or to identify mechanical vibrations of the recirculation knots induced by a flow of recirculation bistable associated to operative conditions of the reactor. (Author)

  7. 消毒供应中心质量追溯管理系统设计与应用%Design and Application of Quality Tacing Management System in Central Sterile Supply Department

    Institute of Scientific and Technical Information of China (English)

    曾美凤; 曾宏; 刘承军; 郭国斌

    2011-01-01

    The process of the quality tracing management for the central sterile supply department in the l80th Hospital of PLA is introduced. The development and application of the information management system are explicated. The design functions and operation effectiveness of the system are analyzed selectively, which will provide a certain reference for the informatization management in the similar units.%介绍了解放军第180医院消毒供应中心的质量追溯管理过程,阐述其信息管理系统的开发应用情况,主要分析该系统的功能设计及其运行效果,为同类单位的信息化管理提供一定的借鉴.

  8. Application of bark ash to a mixed forest in central Sweden - effects on soil chemistry, composition of the flora and stem growth

    International Nuclear Information System (INIS)

    In a 60-year-old mixed coniferous stand dominated by Norway spruce on a sandy-silty till, the effects on soil chemistry, field vegetation and stem growth of applying two different ash products were studied during 1995-2002. Eight field plots (30x30 m) were established in early summer 1995, 56 km WNW Sundsvall in Central Sweden on forest land belonging to SCA Skog. One year later, in June 1996, 3 tonnes of pelleted bark ash (A) from a pulp mill factory were applied per hectare on four of these plots. During the production of these ash pellets, 8-10 % of tall oil was added.The other four plots were control plots (K). In July 1996, six more plots were established, in connection to the other eight plots. Two of these new plots were control plots (C), the other four plots were treated with granules (AS) of bark ash and sewage sludge from A sewage-treatment plant in Sundsvall. Two different doses of these granules were used; two plots received 300 kg per plot or 3.3 tonnes/ha (AS3) and two plots received 900 kg per plot or 10 tonnes/ha (AS9). The field vegetation in treatment A and K was inventoried one year before treatment, and one and five years after treatment. In the other treatments (C, AS3 and AS9) the field vegetation was inventoried only one and five years after treatment. Growth measurements (diameter at breast height and height of the trees) were made in connection to the treatments in June-July 1996 and six years later in May 2002. Soil samplings (humus layer, 0-5 cm below humus layer) were performed six years after the treatments. The soil samples were analyzed on pH, electrical conductivity, organic matter, organic carbon and total nitrogen. Six years after the treatments, considerable more ash pellets than ash granules were found on or in the humus layer. Apparently the ash granules disintegrated faster than the ash pellets. The effects on soil chemistry, six years after treatment, were also more apparent on plots treated with ash granules than on plots

  9. Dynamic modelling of future land use change under urbanization and climate change pressures: application to a case study in central Belgium

    Science.gov (United States)

    Jacquemin, I.; Fontaine, C. M.; Dendoncker, N.; François, L.; De Vreese, R.; Marek, A.; Mortelmans, D.; Van Herzele, A.; Devillet, G.

    2012-04-01

    version of the model developed for natural vegetation has been upgraded to include crop systems and pastures. The ABM (Murray-Rust, Journal of Land Use Science, 6(2-3):83-99, 2011) describes the management choices (e.g., crop rotation, intensive agriculture or organic farming, etc) for each land plot, as well as the possible change in their affectation (e.g., conversion of farm fields to residential areas in response to urbanization), under different socio-economic contexts described in the storyline of three scenarios depicting general societal orientations (business-as-usual; market oriented; sustainability oriented). As a result, the ABM produces a dynamic evolution of land use and management options to be passed on to the DVM for further analysis. The outputs from the DVM allow evaluating quantitatively the provision of EGS by each land plot. This DVM-ABM modelling tool is thus able to describe the future evolution of land use and land cover, as well as of EGS production, in the context of socio-economic scenarios. The model is applied to a case study area covering four municipalities located in central Belgium close to Brussels and Leuven. The area is mostly composed of agricultural fields (crops and meadows), residential areas and a large protected forest (Meerdaalbos) and is subject to intense urbanization pressure due to the proximity to Brussels.

  10. Universal central extensions of direct limits of Lie superalgebras

    CERN Document Server

    Neher, Erhard

    2011-01-01

    We show that the universal central extension of a direct limit of perfect Lie superalgebras L_i is (isomorphic to) the direct limit of the universal central extensions of L_i. As an application we describe the universal central extensions of some infinite rank Lie superalgebras.

  11. Using a Remote Sensing-Supported Hydro-Agroecological Model for Field-Scale Simulation of Heterogeneous Crop Growth and Yield: Application for Wheat in Central Europe

    Directory of Open Access Journals (Sweden)

    Tobias B. Hank

    2015-04-01

    Full Text Available The challenge of converting global agricultural food, fiber and energy crop cultivation into an ecologically and economically sustainable production process requires the most efficient agricultural management strategies. Development, control and maintenance of these strategies are highly dependent on temporally and spatially continuous information on crop status at the field scale. This paper introduces the application of a process-based, coupled hydro-agroecological model (PROMET for the simulation of temporally and spatially dynamic crop growth on agriculturally managed fields. By assimilating optical remote sensing data into the model, the simulation of spatial crop dynamics is improved to a point where site-specific farming measures can be supported. Radiative transfer modeling (SLC is used to provide maps of leaf area index from Earth Observation (EO. These maps are used in an assimilation scheme that selects closest matches between EO and PROMET ensemble runs. Validation is provided for winter wheat (years 2004, 2010 and 2011. Field samples validate the temporal dynamics of the simulations (avg. R² = 0.93 and > 700 ha of calibrated combine harvester data are used for accuracy assessment of the spatial yield simulations (avg. RMSE = 1.15 t∙ha−1. The study shows that precise simulation of field-scale crop growth and yield is possible, if spatial remotely sensed information is combined with temporal dynamics provided by land surface process models. The presented methodology represents a technical solution to make the best possible use of the growing stream of EO data in the context of sustainable land surface management.

  12. Performance and reliability of a 30-kW triple-junction photovoltaic receiver for 500X concentrator dish or central receiver applications

    Science.gov (United States)

    Verlinden, P. J.; Lewandowski, A.; Lasich, J. B.

    2006-08-01

    Over the last 15 years, Solar Systems has developed a dense array receiver PV technology for 500X concentrator reflective dish applications. This concentrator PV technology has been successfully deployed at six different locations in Australia, counting for about 1 MWp of installed peak power. A new Multijunction III-V receiver to replace the current silicon Point-Contact solar cells has recently been developed. The new receiver technology is based on high-efficiency (> 32%) Concentrator Ultra Triple Junction (CUTJ) solar cells from Spectrolab, resulting in system power and energy performance improvement of more than 50% compared to the silicon cells. The 0.235 m2 concentrator PV receiver, designed for continuous 500X operation, is composed of 64 dense array modules, and made of series and parallel-connected solar cells, totaling approximately 1,500 cells. The individual dense array modules have been tested under high intensity pulsed light, as well as with concentrated sunlight at the Solar Systems research facility and at the National Renewable Energy Laboratory's High Flux Solar Furnace. The efficiency of the dense array modules ranges from 30% to 36% at 500X (50 W/cm2, AM1.5D low AOD, 21°C). The temperature coefficients for power, voltage and current, as well as the influence of Air Mass on the cell responsivity, were measured. The reliability of the dense array multijunction III-V modules has been studied with accelerated aging tests, such as thermal cycling, damp heat and high-temperature soak, and with real-life high-intensity exposure. The first 33-kWp multijunction III-V receiver was recently installed in a Solar Systems dish and tested in real-life 500X concentrated sunlight conditions. Receiver efficiencies of 30.3% and 29.0% were measured at Standard Operating Conditions and Normal Operating Conditions respectively.

  13. A Central European precipitation climatology – Part II: Application of the high-resolution HYRAS data for COSMO-CLM evaluation

    Directory of Open Access Journals (Sweden)

    Susanne Brienen

    2016-05-01

    of small values. The maximum values of the different indices across the whole HYRAS-PRE domain are underestimated by 3–20 %. The regional variability is not very high but with a slight orographic dependence. Problems with areas of low station density can also be detected. In conclusion, this study shows that good-quality observational data sets at high-resolution are essential for a correct evaluation of the performance of RCMs designed for applications at high spatial resolution.

  14. Comparative water and N fertilizer utilization in fertigation v/s soil application under drip and macro sprinkler systems of spring potatoes utilizing 15N in Central Beqaa, Lebanon

    International Nuclear Information System (INIS)

    The experiment aimed at studying the impact of type of fertilizer application and irrigation techniques on the yield parameters of spring potatoes by using 15N. In 1997 and 1998, a potato crop (Spunta) was planted in a clayey soil in Tell Amara, Central Beqaa, in a randomized block design. It consisted of five treatments and four replicates. The goal of the research was to study the effect of three rates of N fertigation (N1=240, N2=360, N3=480 kg N/ha for 1997 and N1=120, N2=240, N3=360 kg N/ha for 1998) on potato performance and production, comparing full fertigation with conventional fertilizer application and irrigated with drip and macro sprinkler. Water demands and irrigation were scheduled according to the mean annual potential evapotranspiration in 1997 and Class A pan in 1998, and monitored by the neutron probe and tensiometers. The results show that, at harvest, both crops followed the same yield pattern. The highest tuber yield was obtained from N1 and the lowest from N3. These values were 58 ton/ha for 1997 and 32.5 ton/ha for the 1998 trial. The 1998 spring crop was more efficient in terms of N utilization. The reduction of N input in N1 resulted in 90% N-fertilizer recovery. In the treatment with soil N application, drip irrigation saved up to 50% of water and improved the efficiency of removed N. Starting from the 89th day after planting, sprinklers caused a significant difference in NO3- concentration leached beyond 60 cm depth. Thus, fertigation was superior with regard to fertilizer and water saving and it decreased the risk of N building up in the soil and shallow groundwater resulting in pollution. (author)

  15. Preparation and application of central air-conditioner environment-friendly water treatment agents%中央空调环保型水处理剂的研究及应用

    Institute of Scientific and Technical Information of China (English)

    刘玉林

    2011-01-01

    Based upon the water quality characteristics in Zhengzhou and the water quality and scaling analysis of the central air-conditioning circulating water system of Hualian Trade Center,Zhengzhou,a brand new lowphosphorus environment-friendly water treatment agent, HL-08 has been prepared. Its phosphorus (PO43-) content is less than 5%. The static and dynamic experiments as well as its application in central air-conditioning circulating water systems show that HL-08 has good effects on corrosion and scale inhibition. Meanwhile, the wastewater from the circulating water system contains less than 1.0 mg/L phosphorus,which meets the requirements of the discharge standard (GB 8978-1996).%根据郑州华联商贸城中央空调循环水系统的水质情况和结垢分析,结合郑州地区水质特点,制备了一种新型低磷环保型的水质处理剂HL-08,其磷含量≤5%(以PO(3-)4).静态、旋转挂片、动态试验及在中央空调循环水系统中的实际应用结果表明,该处理剂缓蚀阻垢效果良好,循环水排污水中磷质量浓度<1.0mg/L(以P计),符合国标(GB8978-1996)的要求.

  16. Central Laboratories Services

    Data.gov (United States)

    Federal Laboratory Consortium — The TVA Central Laboratories Services is a comprehensive technical support center, offering you a complete range of scientific, engineering, and technical services....

  17. A handbook for solar central receiver design

    Energy Technology Data Exchange (ETDEWEB)

    Falcone, P.K.

    1986-12-01

    This Handbook describes central receiver technology for solar thermal power plants. It contains a description and assessment of the major components in a central receiver system configured for utility scale production of electricity using Rankine-cycle steam turbines. It also describes procedures to size and optimize a plant and discussed examples from recent system analyses. Information concerning site selection criteria, cost estimation, construction, and operation and maintenance is also included, which should enable readers to perform design analyses for specific applications.

  18. Central centrifugal cicatricial alopecia

    OpenAIRE

    Collin Blattner; Dennis C Polley; Frank Ferritto; Elston, Dirk M

    2013-01-01

    Central centrifugal cicatricial alopecia is a common cause of progressive permanent apical alopecia. This unique form of alopecia includes entities previously know as “hot comb alopecia,” “follicular degeneration syndrome,” “pseudopelade” in African Americans and “central elliptical pseudopelade” in Caucasians. The etiology appears to be multifactorial and the condition occurs in all races.

  19. Optimal Central Bank Transparency

    NARCIS (Netherlands)

    van der Cruijsen, C.A.B.; Eijffinger, S.C.W.; Hoogduin, L.H.

    2008-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  20. Optimal central bank transparency

    NARCIS (Netherlands)

    C.A.B. van der Cruijsen; S.C.W. Eijffinger; L. Hoogduin

    2008-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  1. Optimal central bank transparency

    NARCIS (Netherlands)

    C.A.B. van der Cruijsen; S.C.W. Eijffinger; L.H. Hoogduin

    2010-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  2. Central pontine myelinolysis

    Science.gov (United States)

    ... from one nerve to another. The most common cause of central pontine myelinolysis is a quick change in the body's sodium ... The nerve damage caused by central pontine myelinolysis is usually ... The disorder can cause serious long-term (chronic) disability.

  3. Central Diffraction at ALICE

    CERN Document Server

    Lämsä, Jerry W

    2011-01-01

    The ALICE experiment is shown to be well suited for studies of exclusive final states from central diffractive reactions. The gluon-rich environment of the central system allows detailed QCD studies and searches for exotic meson states, such as glueballs, hybrids and new charmonium-like states. It would also provide a good testing ground for detailed studies of heavy quarkonia. Due to its central barrel performance, ALICE can accurately measure the low-mass central systems with good purity. The efficiency of the Forward Multiplicity Detector (FMD) and the Forward Shower Counter (FSC) system for detecting rapidity gaps is shown to be adequate for the proposed studies. With this detector arrangement, valuable new data can be obtained by tagging central diffractive processes.

  4. Central diffraction at ALICE

    Energy Technology Data Exchange (ETDEWEB)

    Laemsae, J W; Orava, R, E-mail: risto.orava@helsinki.fi [Helsinki Insitute of Physics, and Division of Elementary Particle Physics, Department of Physics, PL 64 (Gustaf Haellstroeminkatu 2a), FI-00014 University of Helsinki (Finland)

    2011-02-01

    The ALICE experiment is shown to be well suited for studies of exclusive final states from central diffractive reactions. The gluon-rich environment of the central system allows detailed QCD studies and searches for exotic meson states, such as glueballs, hybrids and new charmonium-like states. It would also provide a good testing ground for detailed studies of heavy quarkonia. Due to its central barrel performance, ALICE can accurately measure the low-mass central systems with good purity. The efficiency of the Forward Multiplicity Detector (FMD) and the Forward Shower Counter (FSC) system for detecting rapidity gaps is shown to be adequate for the proposed studies. With this detector arrangement, valuable new data can be obtained by tagging central diffractive processes.

  5. Organizational centralization in radiology.

    Science.gov (United States)

    Aas, I H Monrad

    2006-01-01

    Traditionally, hospitals have a radiology department, where images are taken and interpretation occurs. Teleradiology makes it possible to capture images in one location and transmit them elsewhere for interpretation. Organizational centralization of radiology interpretations is therefore of interest. Empirical data have been collected in qualitative interviews of 26 resource persons with substantial experience with picture archiving and communication systems and teleradiology, from 12 departments of radiology in Norway. The response rate was 90%. A total of 21 theoretically possible types of centralization of image interpretation were identified, representing combinations of three categories of geographical centralization, and seven categories of centralization according to function. Various advantages and disadvantages of centralization were identified. Organizational changes may be decisive for the future of teleradiology, but it may be wise to plan for change in small steps, since we know little about how broad future organizational changes based on teleradiology will be, or what will decide how far particular organizations will go. PMID:16438776

  6. Novel central nervous system drug delivery systems.

    Science.gov (United States)

    Stockwell, Jocelyn; Abdi, Nabiha; Lu, Xiaofan; Maheshwari, Oshin; Taghibiglou, Changiz

    2014-05-01

    For decades, biomedical and pharmaceutical researchers have worked to devise new and more effective therapeutics to treat diseases affecting the central nervous system. The blood-brain barrier effectively protects the brain, but poses a profound challenge to drug delivery across this barrier. Many traditional drugs cannot cross the blood-brain barrier in appreciable concentrations, with less than 1% of most drugs reaching the central nervous system, leading to a lack of available treatments for many central nervous system diseases, such as stroke, neurodegenerative disorders, and brain tumors. Due to the ineffective nature of most treatments for central nervous system disorders, the development of novel drug delivery systems is an area of great interest and active research. Multiple novel strategies show promise for effective central nervous system drug delivery, giving potential for more effective and safer therapies in the future. This review outlines several novel drug delivery techniques, including intranasal drug delivery, nanoparticles, drug modifications, convection-enhanced infusion, and ultrasound-mediated drug delivery. It also assesses possible clinical applications, limitations, and examples of current clinical and preclinical research for each of these drug delivery approaches. Improved central nervous system drug delivery is extremely important and will allow for improved treatment of central nervous system diseases, causing improved therapies for those who are affected by central nervous system diseases.

  7. The Development and Application of CSG Technology Intelligence Central System%南方电网技术情报中心系统的研发与应用

    Institute of Scientific and Technical Information of China (English)

    龚婷; 周育忠; 韦嵘晖; 王庆红

    2012-01-01

    The primary goal of creating an electric power intelligence system is to set up a scientific and reasonable intelligence work system.This paper introduces the development and application of CSG technology intelligence central system,including its design concept as well as the design and accomplishment of its four function modules.The characteristics of the system are reflected by the humanization intelligence services in its functions of information searching,processing and publishing as well as intelligence topics,intelligence album,original text delivery and SDI(selective dissemination of information) service.%电力情报系统建设的首要目标是建立一套科学的、合理的技术情报工作体系。阐述了南方电网技术情报中心系统的开发及应用,包括系统设计理念及其四大功能模块的设计与实现。该系统的特点体现在信息检索、加工处理和发布、情报专题、情报专辑、原文传递、定题服务等人性化情报服务项目上。

  8. 省级集中电费充值卡系统设计及应用%Design and Application of Provincial-Level Centralized Electricity Charge Prepaid Card System

    Institute of Scientific and Technical Information of China (English)

    欧阳昱

    2015-01-01

    In order to ensure the unified issue, unified management and unified accounting of the electric-ity charge prepaid card in the whole province, based on the unified business application of the whole province and the off-site recharge demands, State Grid Anhui Electric Power Corporation proposes the design thought and the implementation scheme of provincial-level centralized electricity charge prepaid card system, and realizes the payment of electricity charge by the electricity charge prepaid card without the restrictions of time and space, to improve the customer service capacity.%为做好电费充值卡全省统一发行、统一管理、统一核算和异地充值,国网安徽省电力公司基于全省统一业务应用及异地充值需求,提出省级集中电费充值卡系统设计思路与实现方案,实现电费充值卡缴纳电费不受时间、空间的限制,提升客户服务能力。

  9. Imaging central pain syndromes.

    Science.gov (United States)

    Veldhuijzen, Dieuwke S; Greenspan, Joel D; Kim, Jong H; Coghill, Robert C; Treede, Rolf-Detlef; Ohara, Shinji; Lenz, Frederick A

    2007-06-01

    Anatomic, functional, and neurochemical imaging studies have provided new investigative tools in the study of central pain. High-resolution imaging studies allow for precise determination of lesion location, whereas functional neuroimaging studies measure pathophysiologic consequences of injury to the central nervous system. Additionally, magnetic resonance spectroscopy evaluates lesion-induced neurochemical changes in specific brain regions that may be related to central pain. The small number of studies to date precludes definitive conclusions, but the recent findings provide information that either supports or refutes current hypotheses and can serve to generate new ideas.

  10. Central nervous system

    Science.gov (United States)

    The central nervous system is composed of the brain and spinal cord. Your brain and spinal cord serve as the main "processing center" for your entire nervous system. They control all the workings of your body.

  11. Central Station Design Options

    DEFF Research Database (Denmark)

    2011-01-01

    The purpose of EDISON Work Package 4.1 is the evaluation of possible Central (charging) Stations design options for making possible the public charging of Electric Vehicles (EVs). A number of scenarios for EVs are assessed, with special emphasis on the options of Fast Charging and Battery Swapping....... The work identifies the architecture, sizing and siting of prospective Central Stations in Denmark, which can be located at shopping centers, large car parking lots or gas stations. Central Stations are planned to be integrated in the Danish distribution grid. The Danish island of Bornholm, where a high.......g. due to vandalism, the charge supply circuit is disconnected. More electrical vehicles on the market are capable today of quick charging up to 50 kW power level. The feasibility of Central Stations with fast charging/swapping option, their capacity, design, costs and grid impact, as well as battery...

  12. Central Data Exchange

    Data.gov (United States)

    U.S. Environmental Protection Agency — The Central Data Exchange (CDX) enables fast, efficient and more accurate environmental data submissions from state and local governments, industry and tribes to...

  13. "Central Station" Londonis

    Index Scriptorium Estoniae

    2000-01-01

    Londoni galeriis Milch seitsme läti, leedu ja eesti kunstniku projekt "Central Station". Kuraatorid Lisa Panting, Sally Tallant. Eestist osalevad Hanno Soans (Catarina Campinoga koostöös valminud video), Kiwa, Kai Kaljo

  14. Central Asian Republic Info

    Data.gov (United States)

    US Agency for International Development — CAR Info is designed and managed by the Central Asian Republic Mission to fill in the knowledge and reporting gaps in existing agency systems for that Mission. It...

  15. Central nervous system resuscitation

    DEFF Research Database (Denmark)

    McIntosh, T K; Garde, E; Saatman, K E;

    1997-01-01

    Traumatic injury to the central nervous system induces delayed neuronal death, which may be mediated by acute and chronic neurochemical changes. Experimental identification of these injury mechanisms and elucidation of the neurochemical cascade following trauma may provide enhanced opportunities...

  16. Centralization and political accountability

    OpenAIRE

    Hindriks, Jean; Lockwood, Ben

    2004-01-01

    In this paper we abstract from the usual gains and costs of decentralization (e.g. preference matching, spillovers and economies of scale). Instead we compare the political accountability of decentralized governments relative to centralized ones when there is a risk of "bad" governance. We study both the selection and incentive effects of accountability. A key aspect of centralization is to make the politician answerable to multiple constituencies subject to a common budget constraint. Our ma...

  17. Central Bank independence

    OpenAIRE

    Vasile DEDU; Tiberiu STOICA

    2012-01-01

    In this paper we present the key aspects regarding central bank’s independence. Most economists consider that the factor which positively influences the efficiency of monetary policy measures is the high independence of the central bank. We determined that the National Bank of Romania (NBR) has a high degree of independence. NBR has both goal and instrument independence. We also consider that the hike of NBR’s independence played an important role in the significant disin...

  18. Outsourcing central banking

    DEFF Research Database (Denmark)

    Khoury, Sarkis Joseph; Wihlborg, Clas

    2005-01-01

    The literature on Currency Boards (CB) stops at the water edge in terms of dealing with the totality of the functions of a central bank. Monetary policy, and banking supervisioncan be "outsourced" in an open economy with substantial foreign direct investment (FDI)in the banking sector if political...... the feasibility of, and constraints on, outsourcing of central bank functions. A brief discussion of the Argentinian experience is used for contrast.Key words: Currency Board, Foreign Banks, Supervision, Regional Integration,outsourcing....

  19. 供应链集权管理模式下的RFID在VMI系统中应用的效益分析%Benefit Analysis of Applications of the RFID in the VMI System in Centralized Supply Chain Management Model

    Institute of Scientific and Technical Information of China (English)

    张凯; 马金平

    2012-01-01

    针对在供应链集权管理模式下的RFID在供应商管理库存(VMI)系统中应用的效益分析问题,建立了VMI系统效益分析的概率分布函数。通过对模型的理论分析和数值计算,文章的结论是:当企业保持库存水平一定时,随着RFID标签成本降低,VMI系统利润增加;当RFID标签成本一定时,随着库存容量增加,VMI系统利润降低。这个结论为企业应用RFID的决策提供了科学依据。%Aiming at benefit analysis issue of Applications of the RFID in the VMI System in Centralized-Supply Chain Management Model, this article established probability distribution function of the benefit analysis for VMI system. By the theory analysis of the model and numerical calcu- lation, the conclusion of the article is that firms keep stock level be the same, with reduction of RFID tag cost, profits of the VMI system be in- creased; and that cost of the RFID tag cost is not changed, with stock capacity be increased, profits of the VMI system to decrease. This conclu- sion of the article provided Scientific basis of decision for firm to use RFID.

  20. Application of lean management in operation processing of central sterile supply department%精益管理在消毒供应中心操作流程中的应用

    Institute of Scientific and Technical Information of China (English)

    张炼英

    2011-01-01

    目的 探讨精益管理在消毒供应中心操作流程中的应用,以促进消毒供应中心的效率与品质改善。方法 通过国内外精益思想、精益医疗管理文献与资料的收集与整理,归纳介绍目前国内外精益管理在医疗领域的应用,对消毒供应中心实施精益管理进行探讨。结果 通过制定价值流图,流动作业,消除浪费,取得最高管理者的全力支持,从组织结构上、人员设置上、技能操作上进行变革,充分保证精益管理成功的实施。结论 通过在消毒供应中心建立价值流图分析,并利用信息技术可改善消毒供应中心消毒供应作业的流动性,重建消毒供应管理系统的业务模型,改进消毒供应的效率和质量。%Objective To study the application of lean management in operation processing of central sterile supply department(CSSD)in order to promote its efficiency and quality improvement. Methods From collecting international and domestic related literatures of lean thoughts, lean medical management, summarizing and introducing the application of lean management in medical domain, discussing the implementation of lean management in CSSD. Results The implementation of lean management was ensured to be successful through establishing value stream mapping, mobile operation, waste elimination, obtaining support of top management, reforming of organization construction, placing personal and technological operation. Conclusions The flow of operation can be improved, the business model will be re-build and the efficiency and quality of CSSD can be improved by establishing the value stream mapping in CSSD and using the information technology.

  1. CENTRAL PLATEAU REMEDIATION

    Energy Technology Data Exchange (ETDEWEB)

    ROMINE, L.D.

    2006-02-01

    A systematic approach to closure planning is being implemented at the Hanford Site's Central Plateau to help achieve the goal of closure by the year 2035. The overall objective of Central Plateau remediation is to protect human health and the environment from the significant quantity of contaminated material that resulted from decades of plutonium production in support of the nation's defense. This goal will be achieved either by removing contaminants or placing the residual contaminated materials in a secure configuration that minimizes further migration to the groundwater and reduces the potential for inadvertent intrusion into contaminated sites. The approach to Central Plateau cleanup used three key concepts--closure zones, closure elements, and closure process steps--to create an organized picture of actions required to complete remediation. These actions were merged with logic ties, constraints, and required resources to produce an integrated time-phased schedule and cost profile for Central Plateau closure. Programmatic risks associated with implementation of Central Plateau closure were identified and analyzed. Actions to mitigate the most significant risks are underway while high priority remediation projects continue to make progress.

  2. Colloquium on Central Asia

    International Nuclear Information System (INIS)

    This colloquium on Azerbaijan was organized by the direction of international relations of the French Senate and the French center of foreign trade (CFCE). This document gathers the interventions of the participants and the debates with the audience following these interventions. The topics treated concern: - the present day political-economical situation of Central Asia countries (problem of borders, relations with Russia and China); - the economies of Central Asia countries: short term problems and medium-term perspectives; - the relations with the European Union (political, economical, trade and investments, perspectives); - the European energy stakes of Caspian sea (oil and gas reserves, development of hydrocarbon resources, exploitation and transport constraints, stakes for Europe and France); - TotalFinaElf company in Central Asia (Kazakhstan, Azerbaijan, enclavement problem); - the economical impacts of the TRACECA pathway (Transport Corridor Europe Caucasus Asia). (J.S.)

  3. SOCRATES Invades Central Europe

    Directory of Open Access Journals (Sweden)

    Joseph Slowinski

    1998-04-01

    Full Text Available The objective of this article is to explore the current reality faced by higher education students in Central and Eastern Europe and to draw out the implications of this current reality for policy makers in the future. In the article, I explore the influence of transnational corporations' training programs on education as it currently pertains to Central and Eastern European higher education and employment. In addition, multinational corporate entities exercise influence on European Union policy through the role of lobby organizations and activities. I explore the influence of these practices on education with an emphasis on the emerging importance of Western language skills. In addition, I focus on the European Union and its efforts to expand into Central and Eastern Europe in order to provide a focal point for analysis.

  4. The Naive Central Banker

    Directory of Open Access Journals (Sweden)

    Marcelo de Carvalho Griebeler

    2015-09-01

    Full Text Available There has been in some countries a trend of assigning other functions to central banks besides price stability. The most suggested function to be added to monetary authority’s obligations is to pursue economic growth or full employment. In this paper we characterize the behavior and analyse the optimal monetary policy of, what we call, a naive central banker. We describe the naive behavior as one that does face the inflation-unemployment trade-off, but it tries to minimize both variables simultaneously. Our findings, both under discretion and commitment, indicate that the naive central banker delivers lower expected inflation and inflation variance than the benchmark behavior whenever the economy is rigid enough. However, the degree of conservativeness also affects this result, such that the less conservative the naive policymaker, the more rigidity is necessary.

  5. Hale Central Peak

    Science.gov (United States)

    2004-01-01

    19 September 2004 This Mars Global Surveyor (MGS) Mars Orbiter Camera (MOC) image shows some of the mountains that make up the central peak region of Hale Crater, located near 35.8oS, 36.5oW. Dark, smooth-surfaced sand dunes are seen to be climbing up the mountainous slopes. The central peak of a crater consists of rock brought up during the impact from below the crater floor. This autumn image is illuminated from the upper left and covers an area approximately 3 km (1.9 mi) across.

  6. Central Bank independence

    Directory of Open Access Journals (Sweden)

    Vasile DEDU

    2012-08-01

    Full Text Available In this paper we present the key aspects regarding central bank’s independence. Most economists consider that the factor which positively influences the efficiency of monetary policy measures is the high independence of the central bank. We determined that the National Bank of Romania (NBR has a high degree of independence. NBR has both goal and instrument independence. We also consider that the hike of NBR’s independence played an important role in the significant disinflation process, as headline inflation dropped inside the targeted band of 3% ± 1 percentage point recently.

  7. Several Centuries of Centrality

    OpenAIRE

    Roth, Dana L.

    2015-01-01

    As Carolyn Bertozzi mentioned in her inaugural editorial, the relationship of “Central Science” to “Chemistry” became popularized over 40 years ago with the publication of the first edition of Brown and LeMay’s Chemistry: The Central Science, now in its 13th edition. Yet as late as 2003, Prof. Sason Shaik at The Hebrew University claimed “popularization of chemistry remains scant.” He goes on to share [his] “own experience of popularizing chemistry by delivering the following universal messag...

  8. ORIC central region calculations

    International Nuclear Information System (INIS)

    The central region for the K = 100 Oak Ridge Isochronous Cyclotron, ORIC, will be modified to provide better orbit centering, focusing of orbits in the axial direction, and phase selection, in order to improve extraction efficiency, and reduce radioactive activation of cyclotron components. The central region is specifically designed for the acceleration of intense light ion beams such as 60 MeV protons and 15--100 MeV alphas. These beams will be used in the production of radioactive atoms in the Radioactive Ion Beam Project at Oak Ridge National Laboratory

  9. Results in energy saving obtained with the application of speed variator in fossil power stations; Resultados de ahorro de energia obtenidos con la aplicacion de variadores de velocidad en centrales termoelectricas

    Energy Technology Data Exchange (ETDEWEB)

    Merlos Rueda, Rosa Maria [Programa de Ahorro de Energia del Sector Electrico (PAESE), Mexico, D. F. (Mexico)

    1999-07-01

    The project of installation of speed variator in fossil power stations (CT's) of Comision Federal de Electricidad (CFE), as an energy saving measure, is a pilot project that began with the support of the Subdivision de Generacion, and promoted by the Energy Saving Program of the Electric Sector (PAESE), with the putting in operation of an equipment in the condensate pump of the Punta Prieta II C. T. U3. The energy saving observed was substantial, fluctuating between the 19.4% at high loads (at 90% load) and the 71.1% at low loads (at 40% load) of the generating unit. With these results, it was decided to extend the scope of the project with the installation of 6 more equipment for equal number of fossil power stations, located in 4 of the 5 Regions of Generation. The fossil power stations, selected for this stage of the project were: C. T. Felipe Carrillo Puerto U1, C.T. Lerma U4, C.T. Salamanca U1, C.T. Monterrey U6, C.T. Francisco Villa U3 and the C.T. Punta Prieta II-U1. The equipment was in operation during the first quarter of 1998, and the first results indicate an energy savings average per equipment, between 39% and 52%. The recovery of the investment fluctuates between the 48.4% and the 87.6% in less than two years of operation, with which a maximum period of recovery of 3 years is expected. The estimated potential of energy saving, considering the application of these devices in condensate pumps, feedwater pumps (where no speed variator is installed) forced draft fans, induced draft fans and gas recirculation fans, as well as circulation water pumps, of the existing Generating Power stations, ascends to an annual total of 830,000, which represents an approximate 9.4% of the National consumption of self services. [Spanish] El proyecto de instalacion de variadores de velocidad en Centrales Termoelectricas (CT's) de la Comision Federal de Electricidad (CFE), como medida de ahorro de energia, es un proyecto piloto que se inicio con el apoyo de la

  10. Central arterial pressure assessment with intensity POF sensor

    Science.gov (United States)

    Leitão, Cátia; Gonçalves, Steve; Antunes, Paulo; Bastos, José M.; Pinto, João. L.; André, Paulo

    2015-09-01

    The central pressure monitoring is considered a new key factor in hypertension assessment and cardiovascular prevention. In this work, it is presented the central arterial systolic pressure assessment with an intensity based POF sensor. The device was tested in four subjects, and stable pulse waves were obtained, allowing the calculation of the central pressure for all the subjects. The results shown that the sensor performs reliably, being a simple and low-cost solution to the intended application.

  11. Community centrality and social science research.

    Science.gov (United States)

    Allman, Dan

    2015-12-01

    Community centrality is a growing requirement of social science. The field's research practices are increasingly expected to conform to prescribed relationships with the people studied. Expectations about community centrality influence scholarly activities. These expectations can pressure social scientists to adhere to models of community involvement that are immediate and that include community-based co-investigators, advisory boards, and liaisons. In this context, disregarding community centrality can be interpreted as failure. This paper considers evolving norms about the centrality of community in social science. It problematises community inclusion and discusses concerns about the impact of community centrality on incremental theory development, academic integrity, freedom of speech, and the value of liberal versus communitarian knowledge. Through the application of a constructivist approach, this paper argues that social science in which community is omitted or on the periphery is not failed science, because not all social science requires a community base to make a genuine and valuable contribution. The utility of community centrality is not necessarily universal across all social science pursuits. The practices of knowing within social science disciplines may be difficult to transfer to a community. These practices of knowing require degrees of specialisation and interest that not all communities may want or have.

  12. Community centrality and social science research.

    Science.gov (United States)

    Allman, Dan

    2015-12-01

    Community centrality is a growing requirement of social science. The field's research practices are increasingly expected to conform to prescribed relationships with the people studied. Expectations about community centrality influence scholarly activities. These expectations can pressure social scientists to adhere to models of community involvement that are immediate and that include community-based co-investigators, advisory boards, and liaisons. In this context, disregarding community centrality can be interpreted as failure. This paper considers evolving norms about the centrality of community in social science. It problematises community inclusion and discusses concerns about the impact of community centrality on incremental theory development, academic integrity, freedom of speech, and the value of liberal versus communitarian knowledge. Through the application of a constructivist approach, this paper argues that social science in which community is omitted or on the periphery is not failed science, because not all social science requires a community base to make a genuine and valuable contribution. The utility of community centrality is not necessarily universal across all social science pursuits. The practices of knowing within social science disciplines may be difficult to transfer to a community. These practices of knowing require degrees of specialisation and interest that not all communities may want or have. PMID:26440071

  13. Retiring the central executive.

    Science.gov (United States)

    Logie, Robert H

    2016-10-01

    Reasoning, problem solving, comprehension, learning and retrieval, inhibition, switching, updating, or multitasking are often referred to as higher cognition, thought to require control processes or the use of a central executive. However, the concept of an executive controller begs the question of what is controlling the controller and so on, leading to an infinite hierarchy of executives or "homunculi". In what is now a QJEP citation classic, Baddeley [Baddeley, A. D. (1996). Exploring the central executive. Quarterly Journal of Experimental Psychology, 49A, 5-28] referred to the concept of a central executive in cognition as a "conceptual ragbag" that acted as a placeholder umbrella term for aspects of cognition that are complex, were poorly understood at the time, and most likely involve several different cognitive functions working in concert. He suggested that with systematic empirical research, advances in understanding might progress sufficiently to allow the executive concept to be "sacked". This article offers an overview of the 1996 article and of some subsequent systematic research and argues that after two decades of research, there is sufficient advance in understanding to suggest that executive control might arise from the interaction among multiple different functions in cognition that use different, but overlapping, brain networks. The article concludes that the central executive concept might now be offered a dignified retirement.

  14. Ecodesign in Central America

    NARCIS (Netherlands)

    Crul, M.R.M.

    2003-01-01

    This PhD thesis describes and analyses the change process started by the Ecodesign project in Central America, executed between 1998 and 2002. The project started using the concept and praxis developed in Europe. Nine ecodesign projects were performed in industry, and ecodesign was introduced to cou

  15. Retiring the central executive.

    Science.gov (United States)

    Logie, Robert H

    2016-10-01

    Reasoning, problem solving, comprehension, learning and retrieval, inhibition, switching, updating, or multitasking are often referred to as higher cognition, thought to require control processes or the use of a central executive. However, the concept of an executive controller begs the question of what is controlling the controller and so on, leading to an infinite hierarchy of executives or "homunculi". In what is now a QJEP citation classic, Baddeley [Baddeley, A. D. (1996). Exploring the central executive. Quarterly Journal of Experimental Psychology, 49A, 5-28] referred to the concept of a central executive in cognition as a "conceptual ragbag" that acted as a placeholder umbrella term for aspects of cognition that are complex, were poorly understood at the time, and most likely involve several different cognitive functions working in concert. He suggested that with systematic empirical research, advances in understanding might progress sufficiently to allow the executive concept to be "sacked". This article offers an overview of the 1996 article and of some subsequent systematic research and argues that after two decades of research, there is sufficient advance in understanding to suggest that executive control might arise from the interaction among multiple different functions in cognition that use different, but overlapping, brain networks. The article concludes that the central executive concept might now be offered a dignified retirement. PMID:26821744

  16. Testing for central symmetry

    NARCIS (Netherlands)

    Einmahl, John; Gan, Zhuojiong

    2016-01-01

    Omnibus tests for central symmetry of a bivariate probability distribution are proposed. The test statistics compare empirical measures of opposite regions. Under rather weak conditions, we establish the asymptotic distribution of the test statistics under the null hypothesis; it follows that they a

  17. Central areolar choroidal dystrophy.

    NARCIS (Netherlands)

    Boon, C.J.F.; Klevering, B.J.; Cremers, F.P.M.; Zonneveld-Vrieling, M.N.; Theelen, T.; Hollander, A.I. den; Hoyng, C.B.

    2009-01-01

    OBJECTIVE: To describe the clinical characteristics, follow-up data and molecular genetic background in a large group of patients with central areolar choroidal dystrophy (CACD). DESIGN: Retrospective case series study. PARTICIPANTS: One hundred three patients with CACD from the Netherlands. METHODS

  18. Centralized surveillance and control of satellite networks

    Science.gov (United States)

    Rzewnicki, S. E.; McBeath, J. W.; Brostrup-Jensen, P.

    Satellite based services and networks are increasing in number. This paper describes how such networks can be operated efficiently using software based systems to do satellite transmission surveillance and remote earth station status, alarm and control monitoring at a centralized operations control center. Arrangements are available to accomplish real time, customer controlled configuration of space segments and earth station equipment. Application of the system elements satellite transmission surveillance, alarm and control central, earth station remote, and customer control terminals - to a number of typical networks is described.

  19. Applying IFRS 9 to Central Banks Foreign Reserves

    OpenAIRE

    World Bank

    2016-01-01

    Effective January 1, 2018, IFRS 9 Financial Instruments will replace IAS 39 Financial Instruments: Recognition and Measurement (IAS 39). Unlike most publications on IFRS 9, this paper focuses primarily on the application of the new standard on central banks’ foreign reserve assets, which increasingly constitute a substantial part of central banks’ balance sheet. Based on IFRS 9 implementa...

  20. 应用心房内心电图辅助PICC导管尖端定位的效果评价%The clinical application of intraatrial electrocardiogram-assisted Peripherally lnserted Central Catheter tip positioning technology

    Institute of Scientific and Technical Information of China (English)

    姜桂春

    2016-01-01

    目的:评价心房内心电图辅助PICC导管尖端定位的临床应用效果。方法:将我院2015年1-9月入院的1000例患者按抽签法随机分为对照组和实验组,两组均采用常规方法进行导管置入,两组患者在置管结束后均进行X线片定位确定导管尖端位置,而实验组在置管过程中增加应用心房内心电图辅助技术进行导管尖端定位,比较两组导管尖端的异位率及导管尖端位于理想位置的比例。结果:实验组导管尖端异位率比对照组低(χ2=30.548,P<0.001);不同置管静脉中两组导管尖端异位率均存在统计学差异(P<0.05);实验组导管尖端位于理想位置的比例高于对照组(P<0.05)。结论:应用心房内心电图辅助PICC导管尖端定位,可有效降低导管尖端的异位率,在判断导管尖端位于理想位置的灵敏度高。%Objective: To explore the clinical application of intraatrial electrocardiogram-assisted Peripherally lnserted Central Catheter (PICC) tip positioning technology. Methods: Totally 1000 hospitalized patients were recruited from January 2015 to September and randomly divided into the control group and the experimental group by random sampling method. The patients in two groups were catheterized using conventional method and the catheter tip position were determined by X-rays, while the experimental group added intra-atrial electrocardiogram assisted PICC tip positioning technology to position catheter tip. We compared the catheter heterotopia rate and the sensitivity of catheter tip located in the superior vena cava between the two groups. Results: The catheter heterotopia rate in the experimental group was signiifcantly lower than that in the control group (2= 30.548,P<0.001), while the sensitivity of catheter tip located in the superior vena cava had signiifcant difference (P<0.05). Conclusion: The application of intraatrial electrocardiogram-assisted PICC tip positioning

  1. Forward central jets correlations

    International Nuclear Information System (INIS)

    The azimuthal correlation between forward and central jets has been measured in pp collisions with the CMS detector at the LHC at the centre-of-mass energy of 7 TeV. The forward jet is required to be reconstructed in the hadronic forward calorimeter, within the pseudo-rapidity 3.2t>35 GeV. The measurement of the azimuthal angle between the jets is performed for different separations in pseudo-rapidity between the jets, with the largest separation being 7.5 units. The measurement is repeated for two subsamples of events, one in which an additional jet is required between the forward and the central jet, and one where the additional jet is vetoed. The measurement is compared to several different Monte Carlo models and tunes.

  2. Dry needling - peripheral and central considerations.

    Science.gov (United States)

    Dommerholt, Jan

    2011-11-01

    Dry needling is a common treatment technique in orthopedic manual physical therapy. Although various dry needling approaches exist, the more common and best supported approach targets myofascial trigger points. This article aims to place trigger point dry needling within the context of pain sciences. From a pain science perspective, trigger points are constant sources of peripheral nociceptive input leading to peripheral and central sensitization. Dry needling cannot only reverse some aspects of central sensitization, it reduces local and referred pain, improves range of motion and muscle activation pattern, and alters the chemical environment of trigger points. Trigger point dry needling should be based on a thorough understanding of the scientific background of trigger points, the differences and similarities between active and latent trigger points, motor adaptation, and central sensitize application. Several outcome studies are included, as well as comments on dry needling and acupuncture.

  3. Central simple Poisson algebras

    Institute of Scientific and Technical Information of China (English)

    SU; Yucai; XU; Xiaoping

    2004-01-01

    Poisson algebras are fundamental algebraic structures in physics and symplectic geometry. However, the structure theory of Poisson algebras has not been well developed. In this paper, we determine the structure of the central simple Poisson algebras related to locally finite derivations, over an algebraically closed field of characteristic zero.The Lie algebra structures of these Poisson algebras are in general not finitely-graded.

  4. FNAL central email systems

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Jack; Lilianstrom, Al; Pasetes, Ray; Hill, Kevin; /Fermilab

    2004-10-01

    The FNAL Email System is the primary point of entry for email destined for an employee or user at Fermilab. This centrally supported system is designed for reliability and availability. It uses multiple layers of protection to help ensure that: (1) SPAM messages are tagged properly; (2) All mail is inspected for viruses; and (3) Valid mail gets delivered. This system employs numerous redundant subsystems to accomplish these tasks.

  5. Measuring Central Bank Communication:

    OpenAIRE

    David Lucca; Francesco Trebbi

    2008-01-01

    We present a new automated, objective and intuitive scoring method to measure the content of central bank communication about future policy rate moves. We apply the methodology to statements released by the Federal Open Market Commitee (FOMC) after monetary policy meetings. Using high-frequency financial data, we find that yields on short-term risk-free nominal rates respond both to changes in policy rates and the content of the statements, whereas, medium and long-term rates only respond to ...

  6. Central nervous system diseases

    International Nuclear Information System (INIS)

    It is shown that roentgenological examination plays an important role in diagnosis of central nervous system diseases in children. The methods of roentgenological examinations are divided into 3 groups: roentgenography without contrast media (conventional roentgenography), roentgenography with artificial contrasting of liquor space (ventriculopneumoencelography, myelography) and contrasting of brain and spinal blood vessels (angiography). Conventional contrastless roentgenography of skull and vertebral column occupies leadership in diagnosis of brain neoplasms and some vascular diseases

  7. Centrally Banked Cryptocurrencies

    OpenAIRE

    Danezis, George; Meiklejohn, Sarah

    2015-01-01

    Current cryptocurrencies, starting with Bitcoin, build a decentralized blockchain-based transaction ledger, maintained through proofs-of-work that also generate a monetary supply. Such decentralization has benefits, such as independence from national political control, but also significant limitations in terms of scalability and computational cost. We introduce RSCoin, a cryptocurrency framework in which central banks maintain complete control over the monetary supply, but rely on a distribut...

  8. Centrally Banked Cryptocurrencies

    OpenAIRE

    Danezis, G.; Meiklejohn, S.

    2016-01-01

    Current cryptocurrencies, starting with Bitcoin, build a decentralized blockchain-based transaction ledger, maintained through proofs-of-work that also serve to generate a monetary supply. Such decentralization has benefits, such as independence from national political control, but also significant limitations in terms of computational costs and scalability. We introduce RSCoin, a cryptocurrency framework in which central banks maintain complete control over the monetary supply, but rely on...

  9. Centrality Measures in Networks

    CERN Document Server

    Bloch, Francis; Tebaldi, Pietro

    2016-01-01

    We show that although the prominent centrality measures in network analysis make use of different information about nodes' positions, they all process that information in an identical way: they all spring from a common family that are characterized by the same simple axioms. In particular, they are all based on a monotonic and additively separable treatment of a statistic that captures a node's position in the network.

  10. Spherical explosion with central energy source

    CERN Document Server

    Masuyama, Miyu; Tsuboki, Yoichiro

    2015-01-01

    We present a novel semi-analytic solution describing the propagation of a spherical blast wave driven by a central energy source. The initial density profile has a power-law function of the distance from the center and the energy is injected only into the central region at a rate given by a power-law function of time. This solution is composed of three regions separated by the contact surface and the shock front. The innermost region is assumed to be uniform and the outside of the contact surface includes the shocked matter described by self-similar solutions. We analytically derive the applicable range of parameters of this solution from requirements to satisfy boundary conditions. We perform numerical simulations for flows with various values of parameters, some of which reside out of the thus derived applicable range, and compare with the semi-analytic solutions.

  11. Spherical explosion with a central energy source

    Science.gov (United States)

    Masuyama, Miyu; Shigeyama, Toshikazu; Tsuboki, Yoichiro

    2016-04-01

    We present a novel semi-analytic solution that describes the propagation of a spherical blast wave driven by a central energy source. The initial density profile has a power-law function of the distance from the center and the energy is injected only into the central region at a rate given by a power-law function of time. This solution is composed of three regions separated by the contact surface and the shock front. The innermost region is assumed to be uniform and the outside of the contact surface includes the shocked matter described by self-similar solutions. We analytically derive the applicable range of parameters of this solution from requirements needed to satisfy the boundary conditions. We perform numerical simulations for flows with various values of parameters, some of which reside out of the thus-derived applicable range, and compare the results with the semi-analytic solutions.

  12. Application analysis of intraoperative blood salvage in various kinds of surgical operations in Changsha Central Hospital%回收式自体输血在各类手术中的应用情况分析

    Institute of Scientific and Technical Information of China (English)

    许靖; 高利臣; 陆昊昌

    2015-01-01

    目的:分析回收式自体输血在各类手术中的使用频率,发现回收式自体输血使用的优势术种,了解该技术在所有手术中使用的概况。方法:回顾性收集我院2012年1月~2015年5月全部术中用血病例(包括回收式自体输血和异体输血),按不同手术分类(27类)。对自体血液回输和异体血液使用例次进行统计,分析回收式自体输血在各类手术中的情况。结果:回收式自体输血(522例)占同期术中(1211例)用血例次的43.10%,回输血量363170mL,占术中用血量的35.21%。其中,分布于神经外科手术(包括颅骨修补,颅脑外伤和非创伤性颅内出血)236例,异位妊娠手术69例,非感染类脊柱手术39例,骨折内固定手术42例,髋关节置换术24例,胸、腹部闭合性损伤手术91例;以上8类手术中应用自体血液回输例次占术中用血总例次的61.17%(501/819),占同期自体血回输例次(522)的95.98%。结论:回收式自体输血在神经外科等8类手术中有较高的使用频率,特别在急诊手术中具有其优势。充分理解和遵循自体血液回输适应证将进一步提高其临床应用价值。%Objective By analysis of the application frequency of intraoperative blood salvage (IBS) in various kinds of surgical operations, to discover the most benefited operation kinds, and to understand the situation of IBS in all kinds of surgi-cal operations. Methods All retrospective cases (including salvage autologous and allogeneic blood transfusion) from January, 2012 to May, 2015 in Changsha Central Hospital were collected and classified according to surgical operation classification (27 kinds). Cases of autologous and allogeneic blood transfusion were counted to analyze the situation of IBS in all kinds of surgical operations. Results 522 cases of IBS accounted for 43.10% of all blood transfusion in the same period. The amount of IBS blood

  13. Central effects of fingolimod.

    Science.gov (United States)

    Cruz, Vítor T; Fonseca, Joaquim

    2014-08-01

    Introduccion. El fingolimod, un modulador del receptor de la esfingosina-1-fosfato (S1P) dotado de un mecanismo de accion novedoso, fue el primer tratamiento oral aprobado para la esclerosis multiple remitente recurrente. Su union a los receptores S1P1 de los linfocitos promueve la retencion selectiva de los linfocitos T virgenes y de memoria central en los tejidos linfoides secundarios, lo que impide su salida hacia el sistema nervioso central (SNC). Asimismo, el fingolimod atraviesa con facilidad la barrera hematoencefalica, y diversos estudios le atribuyen un efecto neuroprotector directo en el SNC. Objetivo. Revisar la informacion disponible acerca de los efectos centrales del fingolimod. Desarrollo. El desequilibrio entre los procesos lesivos y reparadores constituye un reflejo de la desmielinizacion cronica, la degeneracion axonal y la gliosis, y parece contribuir a la discapacidad que la esclerosis multiple acarrea. La facilidad con la que el fingolimod atraviesa la barrera hematoencefalica le permite actuar directamente sobre los receptores S1P localizados en las celulas del SNC. Una vez en el interior del SNC, ocupa los receptores S1P de los oligodendrocitos y de sus celulas precursoras, de los astrocitos, los microgliocitos y las neuronas, fomentando la remielinizacion, la neuroproteccion y los procesos endogenos de regeneracion. La eficacia evidenciada en los ensayos clinicos concuerda con un mecanismo de accion que incluiria efectos directos sobre las celulas del SNC. Conclusiones. Los datos disponibles indican que la eficacia del fingolimod en el tratamiento de la esclerosis multiple se debe a su ambivalencia como molecula inmunomoduladora y moduladora directa de los receptores S1P del SNC. Tanto es asi que estudios recientes le atribuyen efectos neuroprotectores en varios modelos que suscitan expectativas en torno a su posible aplicacion terapeutica en la enfermedad de Alzheimer, el paludismo cerebral y el neuroblastoma, asi como en la neuroproteccion

  14. Flooding in Central Siberia

    Science.gov (United States)

    2002-01-01

    A mixture of snowmelt and ice jams in late May and June of this year caused the Taz River (left) and the Yenisey River (right) in central Siberia to overflow their banks. The flooding can be seen in this image taken on June 11, 2002, by the MODIS (Moderate Resolution Imaging Spectroradiometer) instrument aboard the Terra satellite. Normally, the rivers would resemble thin black lines in MODIS imagery. In the false-color images sage green and rusty orange is land, and water is black. Clouds are white and pink. Credit: Image courtesy Jacques Descloitres, MODIS Land Rapid Response Team at NASA GSFC

  15. Application and management of peripherally inserted central catheter in premature%经外周中心静脉置管在早产儿中的应用与管理

    Institute of Scientific and Technical Information of China (English)

    刘萍; 曹敏; 周熙惠

    2014-01-01

    目的:探讨经外周静脉穿刺中心静脉置管术( PICC)在早产儿的应用及常见并发症的处理。方法回顾性分析2011年10月至2013年6月期间西安交通大学医学院第一附属医院新生儿科重症监护室41例PICC早产儿的置管途径、置管成功率、置管长度、留管时间、并发症及处理方法。结果穿刺部位:肘正中静脉25例,贵要静脉11例,头臂静脉2例,颞浅静脉2例,髂外静脉1例;右侧置管35例,左侧置管6例;一次置管成功率为100%(41/41),置管长度7~12cm,留管时间3h~44d;29例正常拔管,2例导管异位,2例堵管拔管,3例外渗拔管,1例静脉炎,1例细菌培养阳性,2例葡聚糖升高拔管,1例有临床感染症状但细菌培养阴性。结论 PICC操作成功率高、安全、留置时间长,是早产儿较佳的静脉通道;肘正中静脉及贵要静脉是较佳的PICC静脉通路,头臂静脉、颞浅静脉及髂外静脉例数减少,但推测颞浅静脉不宜作为早产儿PICC的静脉通路。%Objective To explore the application of peripherally inserted central catheter (PICC) in premature and treatment of common complications .Methods Retrospective analysis was conducted on 41 premature infants with PICC between October 2011 and June 2013 in neonatal intensive care unit of First Affiliated Hospital of Xi ’ an Jiaotong University , including inserting pathways , success rate , length of tube, tube indwelling time, complications and treatment methods .Results Of 41 cases, 25 cases were inserted from median cubital vein , 11 cases from basilic vein , 2 cases from brachiocephalic vein , 2 cases from superficial temporal vein and 1 case from external iliac vein . There were 35 cases with catheter on right side and 6 cases on left side.The success rate was 100%(41/41), with length of 7-12 cm and tube indwelling time 3h-44d.Extubation of 29 cases were at recovery, and 2 cases underwent extubation for

  16. Centralized vs. De-centralized Multinationals and Taxes

    DEFF Research Database (Denmark)

    Nielsen, Søren Bo; Raimondos-Møller, Pascalis; Schjelderup, Guttorm

    2005-01-01

    The paper examines how country tax differences affect a multinational enterprise's choice to centralize or de-centralize its decision structure. Within a simple model that emphasizes the multiple conflicting roles of transfer prices in MNEs - here, as a strategic pre-commitment device and a tax m...... manipulation instrument -, we show that (de-)centralized decisions are more profitable when tax differentials are (small) large.Keywords: Centralized vs. de-centralized decisions, taxes, MNEs.JEL-Classification: H25, F23, L23....

  17. 3D CENTRAL LINE EXTRACTION OF FOSSIL OYSTER SHELLS

    Directory of Open Access Journals (Sweden)

    A. Djuricic

    2016-06-01

    Full Text Available Photogrammetry provides a powerful tool to digitally document protected, inaccessible, and rare fossils. This saves manpower in relation to current documentation practice and makes the fragile specimens more available for paleontological analysis and public education. In this study, high resolution orthophoto (0.5 mm and digital surface models (1 mm are used to define fossil boundaries that are then used as an input to automatically extract fossil length information via central lines. In general, central lines are widely used in geosciences as they ease observation, monitoring and evaluation of object dimensions. Here, the 3D central lines are used in a novel paleontological context to study fossilized oyster shells with photogrammetric and LiDAR-obtained 3D point cloud data. 3D central lines of 1121 Crassostrea gryphoides oysters of various shapes and sizes were computed in the study. Central line calculation included: i Delaunay triangulation between the fossil shell boundary points and formation of the Voronoi diagram; ii extraction of Voronoi vertices and construction of a connected graph tree from them; iii reduction of the graph to the longest possible central line via Dijkstra’s algorithm; iv extension of longest central line to the shell boundary and smoothing by an adjustment of cubic spline curve; and v integration of the central line into the corresponding 3D point cloud. The resulting longest path estimate for the 3D central line is a size parameter that can be applied in oyster shell age determination both in paleontological and biological applications. Our investigation evaluates ability and performance of the central line method to measure shell sizes accurately by comparing automatically extracted central lines with manually collected reference data used in paleontological analysis. Our results show that the automatically obtained central line length overestimated the manually collected reference by 1.5% in the test set, which

  18. D Central Line Extraction of Fossil Oyster Shells

    Science.gov (United States)

    Djuricic, A.; Puttonen, E.; Harzhauser, M.; Mandic, O.; Székely, B.; Pfeifer, N.

    2016-06-01

    Photogrammetry provides a powerful tool to digitally document protected, inaccessible, and rare fossils. This saves manpower in relation to current documentation practice and makes the fragile specimens more available for paleontological analysis and public education. In this study, high resolution orthophoto (0.5 mm) and digital surface models (1 mm) are used to define fossil boundaries that are then used as an input to automatically extract fossil length information via central lines. In general, central lines are widely used in geosciences as they ease observation, monitoring and evaluation of object dimensions. Here, the 3D central lines are used in a novel paleontological context to study fossilized oyster shells with photogrammetric and LiDAR-obtained 3D point cloud data. 3D central lines of 1121 Crassostrea gryphoides oysters of various shapes and sizes were computed in the study. Central line calculation included: i) Delaunay triangulation between the fossil shell boundary points and formation of the Voronoi diagram; ii) extraction of Voronoi vertices and construction of a connected graph tree from them; iii) reduction of the graph to the longest possible central line via Dijkstra's algorithm; iv) extension of longest central line to the shell boundary and smoothing by an adjustment of cubic spline curve; and v) integration of the central line into the corresponding 3D point cloud. The resulting longest path estimate for the 3D central line is a size parameter that can be applied in oyster shell age determination both in paleontological and biological applications. Our investigation evaluates ability and performance of the central line method to measure shell sizes accurately by comparing automatically extracted central lines with manually collected reference data used in paleontological analysis. Our results show that the automatically obtained central line length overestimated the manually collected reference by 1.5% in the test set, which is deemed

  19. en los pivotes centrales

    Directory of Open Access Journals (Sweden)

    Reynaldo Roque Rodés

    2005-01-01

    Full Text Available Se hace una revisión y comentarios sobre las ventajas y limitantes del empleo del LEPA (Low Enery Precision Aplication en los sistemas de riego de pivotes centrales. Estos sistemas o filosofía de manejo del agua para condiciones de escasez o mala calidad del líquido es una alternativa viable para la producción de alimentos. Introducida en la década del 80 en las planicies del sur de Texas, donde la alta evaporación del agua y la necesidad de regar grandes áreas con pivotes centrales obligaba a la búsqueda de una alternativa para incrementar al máximo la eficiencia de aplicación del riego. Aún en fase de estudio e introducción en Cuba para áreas específicas, puede ser una solución de incremento de los rendimientos de los cultivos, empleando menos agua y aguas con calidad limitada

  20. Central Sumatra enjoys success

    Energy Technology Data Exchange (ETDEWEB)

    Wongsosantiko, A.

    1977-05-02

    The Sihapas group contains the most prolific oil producing zones in the Central Sumatra Basin. It represents the transgressive, coarse clastic sequence deposited during the early Miocene. Some of these sandstone grade laterally into siltstones and shales of the Telisa Formation, believed to be a major source of rock for Central Sumatra oil. Recent exploratory wells drilled between the mountain front and coastal plain areas have provided more data for stratigraphic studies. These have resulted in subdivision of the lower Miocene transgressive sequence into discrete rock-stratigraphic units. The former Sihapas Formation has subsequently been elevated to group rank and now consists of several formations with the Duri Formation as the uppermost sand unit. This study covers Caltex's areas of operation, which includes the area between the Kampar River of the south, the Barumum River to the north, the Malacca Straits to the east, and the Barisan Mt. to the west. A basic map shows the regional scene, while a stratigraphic chart shows the lithology.

  1. Centrality Measures in Urban Networks

    CERN Document Server

    Crucitti, P; Porta, S; Crucitti, Paolo; Latora, Vito; Porta, Sergio

    2005-01-01

    Centrality has revealed crucial for understanding the structural order of complex relational networks. Centrality is also relevant for various spatial factors affecting human life and behaviors in cities. We present a comprehensive study of centrality distributions over geographic networks of urban streets. Four different measures of centrality, namely closeness, betweenness, straightness and information, are compared over eighteen 1-square-mile samples of different world cities. Samples are represented by primal geographic graphs, i.e. valued graphs defined by metric rather than topologic distance where intersections are turned into nodes and streets into edges. The spatial behavior of centrality indexes over the networks is investigated graphically by means of colour-coded maps. The results indicate that a spatial analysis, that we term Multiple Centrality Assessment(MCA), grounded not a single but on a set of different centrality indices, allows an extended comprehension of the city structure, nicely captu...

  2. Centralizer for well casing

    International Nuclear Information System (INIS)

    This patent describes an improved centralizer for centering a well casing in a wellbore. It comprises: a first anchor adapted to fit around and be securely fixed to the casing, the first anchor being threaded on its external surface; a first collar adapted to fit around and be threadedly engaged by the first anchor; a second collar adapted to fit around and free to rotate and move axially with respect to the casing; a second anchor adapted to fit around and be securely fixed to the casing spaced from the first anchor and comprising a bearing surface for restraining axial movement of the second collar along the casing; and metallic straps extending between the first collar and the second collar, and being securely fixed to each

  3. UA2 central calorimeter

    CERN Multimedia

    The UA2 central calorimeter measured the energy of individual particles created in proton-antiproton collisions. Accurate calibration allowed the W and Z masses to be measured with a precision of about 1%. The calorimeter had 24 slices like this one, each weighing 4 tons. The slices were arranged like orange segments around the collision point. Incoming particles produced showers of secondary particles in the layers of heavy material. These showers passed through the layers of plastic scintillator, generating light which was taken by light guides (green) to the data collection electronics. The amount of light was proportional to the energy of the original particle. The inner 23 cm of lead and plastic sandwiches measured electrons and photons; the outer 80 cm of iron and plastic sandwiches measured strongly interacting hadrons. The detector was calibrated by injecting light through optical fibres or by placing a radioactive source in the tube on the bottom edge.

  4. Central solar energy receiver

    Science.gov (United States)

    Drost, M. Kevin

    1983-01-01

    An improved tower-mounted central solar energy receiver for heating air drawn through the receiver by an induced draft fan. A number of vertically oriented, energy absorbing, fin-shaped slats are radially arranged in a number of concentric cylindrical arrays on top of the tower coaxially surrounding a pipe having air holes through which the fan draws air which is heated by the slats which receive the solar radiation from a heliostat field. A number of vertically oriented and wedge-shaped columns are radially arranged in a number of concentric cylindrical clusters surrounding the slat arrays. The columns have two mirror-reflecting sides to reflect radiation into the slat arrays and one energy absorbing side to reduce reradiation and reflection from the slat arrays.

  5. Flooding in Central China

    Science.gov (United States)

    2002-01-01

    During the summer of 2002, frequent, heavy rains gave rise to floods and landslides throughout China that have killed over 1,000 people and affected millions. This false-color image of the western Yangtze River and Dongting Lake in central China was acquired on August 21, 2002, by the Moderate-resolution Imaging Spectroradiometer (MODIS), flying aboard NASA's Terra spacecraft. (right) The latest flooding crisis in China centers on Dingtong Lake in the center of the image. Heavy rains have caused it to swell over its banks and swamp lakefront towns in the province of Hunan. As of August 23, 2002, more than 250,000 people have been evacuated, and over one million people have been brought in to fortify the dikes around the lake. Normally the lake would appear much smaller and more defined in the MODIS image. Credit: Image courtesy Jacques Descloitres, MODIS Land Rapid Response Team at NASA GSFC.

  6. UA1 central detector

    CERN Multimedia

    The UA1 central detector was crucial to understanding the complex topology of proton-antiproton events. It played a most important role in identifying a handful of Ws and Zs among billions of collisions. The detector was a 6-chamber cylindrical assembly 5.8 m long and 2.3 m in diameter, the largest imaging drift chamber of its day. It recorded the tracks of charged particles curving in a 0.7 Tesla magnetic field, measuring their momentum, the sign of their electric charge and their rate of energy loss (dE/dx). Atoms in the argon-ethane gas mixture filling the chambers were ionised by the passage of charged particles. The electrons which were released drifted along an electric field shaped by field wires and were collected on sense wires. The geometrical arrangement of the 17000 field wires and 6125 sense wires allowed a spectacular 3-D interactive display of reconstructed physics events to be produced.

  7. Sucker rod centralizer

    Energy Technology Data Exchange (ETDEWEB)

    Rivas, O.; Newski, A.

    1989-10-03

    This patent describes a device for centralizing at least one sucker rod within a production pipe downhole in a well and for reducing frictional forces between the pipe and at least one sucker rod. It comprises an elongate, substantially cylindrical body member having a longitudinal axis, a plurality of slots within the member and a rotatable member mounted within each slot, each of the plurality of slots has its major dimension along a first axis parallel to the longitudinal axis of the body member and is oriented with respect to the other seats so as to form a helicoidal array for maximizing the total surface contact area between the rotatable members and the pipe and for decreasing the forces acting on each rotatable member.

  8. Central heating: package boilers

    Energy Technology Data Exchange (ETDEWEB)

    Farahan, E.

    1977-05-01

    Performance and cost data for electrical and fossil-fired package boilers currently available from manufacturers are provided. Performance characteristics investigated include: unit efficiency, rated capacity, and average expected lifetime of units. Costs are tabulated for equipment and installation of various package boilers. The information supplied in this report will simplify the process of selecting package boilers required for industrial, commercial, and residential applications.

  9. UPVAPOR: computer application for the analysis of the results of Cofrentes Nuclear Power Plant production; UPVAPOR: Aplicacion informatica para el analisis de resultados de produccion en Central Nuclear Cofrentes

    Energy Technology Data Exchange (ETDEWEB)

    Palomo, M. J.; Baraza Peregrin, A.; Bucho Piqueras, L.; Vaquer Perez, J. I.; Lopez Lopez, B.

    2010-07-01

    UPVapor is a software developed for the Cofrentes Nuclear Power Plant Group of Results. This application presents a graphical environment for analysis in which the user has available many variables registered to configure the graphics. This application saves a lot of time at work because it allows other users to do their own analysis without resorting to analysts.

  10. A partitioned central solar receiver

    International Nuclear Information System (INIS)

    Else of solar energy as substitute for conventional fuels at a competitive cost requires efficient conversion from solar radiation to usable forms of energy. In solar thermal or thermochemical applications, high efficiency usually re- quires high temperature and high concentration of incoming radiation. The main form of energy loss from high temperature solar central receivers is thermal emission ('re radiation'), at an effective temperature close to the maximum receiver temperature. This loss is reduced if the aperture is divided into segments, most of which are maintained at lower temperatures. A two-stage partitioned receiver demonstrating this concept is under construction at the Weizman Solar Tower. The high-temperature stage is the DIAPR (Directly Irradiated Annular Pressurized Receiver). The low-temperature stage is made of tubular cavity receivers of simpler design. Preliminary optical and thermal design of the partitioned receiver is presented. For the design exit temperature of 1500 K, the aperture size of the partitioned receiver is about 60% of the equivalent single-stage receiver, indicating a significant increase of conversion efficiency. The exit temperature of the low-temperature stage is around 1100 K, allowing simpler design and inexpensive construction. (authors)

  11. Centrality measures for networks with community structure

    Science.gov (United States)

    Gupta, Naveen; Singh, Anurag; Cherifi, Hocine

    2016-06-01

    Understanding the network structure, and finding out the influential nodes is a challenging issue in large networks. Identifying the most influential nodes in a network can be useful in many applications like immunization of nodes in case of epidemic spreading, during intentional attacks on complex networks. A lot of research is being done to devise centrality measures which could efficiently identify the most influential nodes in a network. There are two major approaches to this problem: On one hand, deterministic strategies that exploit knowledge about the overall network topology, while on the other end, random strategies are completely agnostic about the network structure. Centrality measures that can deal with a limited knowledge of the network structure are of prime importance. Indeed, in practice, information about the global structure of the overall network is rarely available or hard to acquire. Even if available, the structure of the network might be too large that it is too much computationally expensive to calculate global centrality measures. To that end, a centrality measure is proposed here that requires information only at the community level. Indeed, most of the real-world networks exhibit a community structure that can be exploited efficiently to discover the influential nodes. We performed a comparative evaluation of prominent global deterministic strategies together with stochastic strategies, an available and the proposed deterministic community-based strategy. Effectiveness of the proposed method is evaluated by performing experiments on synthetic and real-world networks with community structure in the case of immunization of nodes for epidemic control.

  12. HIS Central and the Hydrologic Metadata Catalog

    Science.gov (United States)

    Whitenack, T.; Zaslavsky, I.; Valentine, D. W.

    2008-12-01

    The CUAHSI Hydrologic Information System project maintains a comprehensive workflow for publishing hydrologic observations data and registering them to the common Hydrologic Metadata Catalog. Once the data are loaded into a database instance conformant with the CUAHSI HIS Observations Data Model (ODM), the user configures ODM web service template to point to the new database. After this, the hydrologic data become available via the standard CUAHSI HIS web service interface, that includes both data discovery (GetSites, GetVariables, GetSiteInfo, GetVariableInfo) and data retrieval (GetValues) methods. The observations data then can be further exposed via the global semantics-based search engine called Hydroseek. To register the published observations networks to the global search engine, users can now use the HIS Central application (new in HIS 1.1). With this online application, the WaterML-compliant web services can be submitted to the online catalog of data services, along with network metadata and a desired network symbology. Registering services to the HIS Central application triggers a harvester which uses the services to retrieve additional network metadata from the underlying ODM (information about stations, variables, and periods of record). The next step in HIS Central application is mapping variable names from the newly registered network, to the terms used in the global search ontology. Once these steps are completed, the new observations network is added to the map and becomes available for searching and querying. The number of observations network registered to the Hydrologic Metadata Catalog at SDSC is constantly growing. At the time of submission, the catalog contains 51 registered networks, with estimated 1.7 million stations.

  13. 疾病控制论在中枢神经损伤研究中的应用探讨%Discussion about the Application of Disease Cybernetics in the Research of Central Nervous System Injure

    Institute of Scientific and Technical Information of China (English)

    陆志方; 敖强

    2015-01-01

    To discuss and present a new thinking about the research of central nervous system injure based on disease cybernetics and the perfect health service system .There are three stages of the whole process of central nervous system injury ,including prevention ,treatment ,rehabilitation .This article is to analyze the neuroscience research process about research target ,relates to the field ,the focus of cooperation of every stage ,and put forward improvement strategy .The new neuroscience research strategies include:unified goal ,systemic ,horizontal linkages .The strategy based on disease cybernetics may contribute to reduce the incidence and disability of central nervous system injure .%根据疾病控制论的原理和完美医疗目标体系,探讨提出一种针对中枢神经损伤的神经科学研究新思路。编制中枢神经损伤的全流程,包括预防、救治、康复3个阶段,对每个阶段中神经科学的研究目标、涉及领域、合作重点进行分析,提出改进策略。新的神经科学研究策略包括:统一目标、系统性、横向联系。基于疾病控制论提出的新策略,可能有利于降低中枢神经损伤的发生率和致残率。

  14. Application des analyses minéralogiques et géotechniques des Argiles dans l’étude des glissements de terrains: exemples du Prérif central (Maroc septentrional

    Directory of Open Access Journals (Sweden)

    Faleh Ali

    2002-01-01

    Full Text Available En el Prerif central resulta muy común el paisaje de vertientes afectadas por deslizamientos de terrenos, recientes o reactivados. Los factores responsables de esta morfodinámica acelerada están ligados al predominio de rocas blandas, a las precipitaciones intensas e irregulares y a las fuertes pendientes. El objetivo principal de este trabajo es determinar la susceptibilidad de las diferentes facies a los movimientos en masa, en relación con las características mineralógicas y geotécnicas de las arcillas.

  15. Application of Centralized Training Combined with Complementary Companion Study in Training of Stoma Visitor%集中培训联合结伴式互补学习在造口探访员培训中的应用

    Institute of Scientific and Technical Information of China (English)

    蔡一波; 陈秀云; 谢玲女

    2015-01-01

    Objective To evaluate the feasibility and effects of centralized training combined with complementary companion study in stoma visitor training. Methods Six selected stoma visitors received intensive training on theoretical knowledge of stoma visit, then they obtained practical visiting skills in a complementary learning way. Comprehensive evaluation of stoma visitor`s knowledge, visitors’ self-assessment of problem-solving ability and self-care ability of the patients to whom visitors paid a visit after the centralized training. Results The knowledge of six selected stoma visitors was improved after the centralized training. In the process of complementary companion study, problem-solving ability was significantly improved in visitor ’s self-assessment. Self-care ability of the patients was significantly promoted when compared with those without visits. Conclusion Centralized training combined with complementary companion study is practical for the stoma visitor training ,which is of significance and worth to be promoted.%目的:评估集中培训联合结伴式互补学习培训造口探访员的可行性及效果。方法首先招募选拔6名造口探访员,对造口探访相关理论知识进行集中授课培训,而对探访实践技能采用结伴式互补学习的多元化培训方式进行培训,培训结束后,从对探访员知识掌握程度评价、独立解决问题能力的自我评价、被探访者探访后自我护理能力提高效果3个方面进行综合评价。结果6名探访者集中培训后的知识测评分显著高于培训前,在结伴式互补学习过程中,培训6月时探访员自我测评独立解决问题比例显著提高,接受探访患者的自我护理能力显著高于同期未接受探访者。结论集中培训联合结伴式互补学习的培训方法适用对造口探访员的培训,具有推广价值。

  16. Application of ultrasonic combined with Back-propagation neural network in the diagnosis of central precocious puberty%超声结合 BP 神经网络技术诊断女童中枢性性早熟

    Institute of Scientific and Technical Information of China (English)

    梁哲浩; 鲁伟

    2015-01-01

    目的:探讨超声结合人工神经网络技术在女童中枢性性早熟诊断中的应用价值。方法选用170例性早熟女童进行常规超声检查子宫、卵巢,以其中130例的子宫体积、卵巢体积以及双侧卵巢最大卵泡内径为输入变量,以中枢性性早熟或非中枢性性早熟为输出变量,建立反向传播(BP)神经网络,并对另40例性早熟病例分类。结果利用 BP 神经网络结合常规超声检查对中枢性性早熟诊断的敏感性、特异性和准确率分别为95.0%、85.0%、90.0%。结论神经网络结合超声检查对中枢性性早熟的诊断和鉴别诊断具有较大的价值。%Objective To explore the value of ultrasonic combined with Back‐propagation artificial neural network in the diagnosis of central precocious puberty .Methods In 170 girls with precocious puberty ,the uterine and ovarian were ex‐amined with ultrasound ,in which 130 cases of uterine volume ,ovarian volume and bilateral ovarian follicles biggest diame‐ter were taken as inputs ,the central precocious puberty or non‐central precocious puberty as output variable .The back‐propagation (BP) neural network was established using such data .The other 40 cases were sorted by this BP neural net‐work .Results The diagnostic sensitivity ,specificity and accuracy of the BP neural network combination of ultrasound were 95 .0% ,85 .0% and 90 .0% ,respectively .Conclusion The BP neural network in combination of ultrasound is help‐ful in diagnosing central precocious puberty .

  17. Application of central composite design and rank annihilation factor analysis for optimization of mixed chelate of UO{sub 2}{sup 2+} complex with ammonium-N,N-tetramethylenedithiocarbamate and estimation of K{sub f} value

    Energy Technology Data Exchange (ETDEWEB)

    Aslani, Mahmut A.A.; Kuru, Yesim F.; Aslani, Ceren Kutahyali [Ege Univ., Izmir (Turkey). Inst. of Nuclear Sciences

    2016-04-01

    The interaction between UO{sub 2}{sup 2+} and ammonium-N,N-tetramethylenedithiocarbamate (ATMDTC) was investigated experimentally by means of UV-Vis spectrophotometry. Central Composite Design (CCD) was applied to optimisation of reaction with 54 runs in duplicate. This design type was also used to developed mathematical model equation. Analysis of Variance (ANOVA) indicates that the terms of the model are significant within the 95% confident interval. Remarkably initial solution pH, initial ATMDTC concentration, initial Cu{sup 2+} concentration and temperature have effect on the reaction. Formation constant (log K{sub f}) was calculated as 2.917 by using Rank Annihilation Factor Analysis (RAFA).

  18. 集中培训联合结伴式互补学习在造口探访员培训中的应用%Application of Centralized Training Combined with Complementary Companion Study in Training of Stoma Visitor

    Institute of Scientific and Technical Information of China (English)

    蔡一波; 陈秀云; 谢玲女

    2015-01-01

    目的:评估集中培训联合结伴式互补学习培训造口探访员的可行性及效果。方法首先招募选拔6名造口探访员,对造口探访相关理论知识进行集中授课培训,而对探访实践技能采用结伴式互补学习的多元化培训方式进行培训,培训结束后,从对探访员知识掌握程度评价、独立解决问题能力的自我评价、被探访者探访后自我护理能力提高效果3个方面进行综合评价。结果6名探访者集中培训后的知识测评分显著高于培训前,在结伴式互补学习过程中,培训6月时探访员自我测评独立解决问题比例显著提高,接受探访患者的自我护理能力显著高于同期未接受探访者。结论集中培训联合结伴式互补学习的培训方法适用对造口探访员的培训,具有推广价值。%Objective To evaluate the feasibility and effects of centralized training combined with complementary companion study in stoma visitor training. Methods Six selected stoma visitors received intensive training on theoretical knowledge of stoma visit, then they obtained practical visiting skills in a complementary learning way. Comprehensive evaluation of stoma visitor`s knowledge, visitors’ self-assessment of problem-solving ability and self-care ability of the patients to whom visitors paid a visit after the centralized training. Results The knowledge of six selected stoma visitors was improved after the centralized training. In the process of complementary companion study, problem-solving ability was significantly improved in visitor ’s self-assessment. Self-care ability of the patients was significantly promoted when compared with those without visits. Conclusion Centralized training combined with complementary companion study is practical for the stoma visitor training ,which is of significance and worth to be promoted.

  19. [Central auditory prosthesis].

    Science.gov (United States)

    Lenarz, T; Lim, H; Joseph, G; Reuter, G; Lenarz, M

    2009-06-01

    Deaf patients with severe sensory hearing loss can benefit from a cochlear implant (CI), which stimulates the auditory nerve fibers. However, patients who do not have an intact auditory nerve cannot benefit from a CI. The majority of these patients are neurofibromatosis type 2 (NF2) patients who developed neural deafness due to growth or surgical removal of a bilateral acoustic neuroma. The only current solution is the auditory brainstem implant (ABI), which stimulates the surface of the cochlear nucleus in the brainstem. Although the ABI provides improvement in environmental awareness and lip-reading capabilities, only a few NF2 patients have achieved some limited open set speech perception. In the search for alternative procedures our research group in collaboration with Cochlear Ltd. (Australia) developed a human prototype auditory midbrain implant (AMI), which is designed to electrically stimulate the inferior colliculus (IC). The IC has the potential as a new target for an auditory prosthesis as it provides access to neural projections necessary for speech perception as well as a systematic map of spectral information. In this paper the present status of research and development in the field of central auditory prostheses is presented with respect to technology, surgical technique and hearing results as well as the background concepts of ABI and AMI. PMID:19517084

  20. Centralizers in simple locally finite groups

    Directory of Open Access Journals (Sweden)

    Mahmut Kuzucuoğlu

    2013-03-01

    Full Text Available This is a survey article on centralizers of finitesubgroups in locally finite, simple groups or LFS-groups as wewill call them. We mention some of the open problems aboutcentralizers of subgroups in LFS-groups and applications of theknown information about the centralizers of subgroups to thestructure of the locally finite group. We also prove thefollowing: Let $G$ be a countably infinite non-linear LFS-groupwith a Kegel sequence $mathcal{K}={(G_i,N_i | iinmathbf{N} }$. If there exists an upper bound for ${ |N_i| |iin mathbf{N} }$, then for any finite semisimplesubgroup $F$ in $G$ the subgroup $C_G(F$ has elements oforder $p_i$ for infinitely many distinct prime $p_i$. Inparticular $C_G(F$ is an infinite group. This answers Hartley'squestion provided that there exists a bound on ${ |N_i| | iin mathbf{N}$.

  1. 立体定向放疗应用于中央型肺癌的剂量学研究%Dosimetry study of stereospecific radiotherapy application in central lung cancer

    Institute of Scientific and Technical Information of China (English)

    杨有文; 张海亮

    2015-01-01

    Objective To investigate the dosimetric differences of central lung stereospecific radiotherapy (SBRT) under 3-dimensional conformal (3-DCRT) and intensity modulated radiation therapy (IMRT). Methods 106 patients with central lung cancer in our hospital were given 3-DCRT and IMRT designed SBRT, their related pa-rameters of the two plans were compared. Results There was no significance in Dmean, Dmax, Dmin, and HI val-ues between the two methods (P > 0. 05). The value of CI was worse in the 3-DCRT group than in the IMRT group (P 0.05),3-DCRT 计划的 CI 差于 IMRT 计划(P 0.05)。结论 SBRT 应用于中央型肺癌满足剂量学要求,相对于3-DCRT,IMRT 在早期中央型非小细胞肺癌 SBRT 并不具明显剂量学优势。

  2. Energy-saving Measures of Central Air Conditioning System -Applications of Secondary Return Air System%中央空调系统的节能措施--二次回风系统的应用

    Institute of Scientific and Technical Information of China (English)

    刘国榕

    2013-01-01

    At present , the constant temperature&humidity central air -conditioning system general adopt the pri-mary return air system .If adopt the secondary return air system instead , the heating capacity of the heater and equal cooling capacity can be saved .Therefore, adopt the secondary return air system , the energy saving effect will be ver-y remarkable .After this kind of the central air -conditioning system is put into operation , the energy saving effect is also proved.Projects completed and put into operation also proved this .%目前恒温恒湿中央空调工程普遍采用一次回风系统,如改用二次回风系统,将可以节省加热器的加热量及与加热量相同数量的制冷量,因此采用二次回风系统有显著的节能效果。工程实例建成投入运行后的运行结果也得到证明。

  3. Solar power tower design guide: Solar thermal central receiver power systems. A source of electricity and/or process heat

    Science.gov (United States)

    Battleson, K. W.

    1981-04-01

    Preliminary evaluations of whether a solar thermal central receiver plant is technically and economically feasible and desirable, for the potential user's application are reported. The cost elements, performance, and operation of solar central receiver systems are described.

  4. Centrality Fingerprints for Power Grid Network Growth Models

    CERN Document Server

    Gurfinkel, Aleks Jacob; Rikvold, Per Arne

    2015-01-01

    In our previous work, we have shown that many of the properties of the Florida power grid are reproduced by deterministic network growth models based on the minimization of energy dissipation $E_\\mathrm{diss}$. As there is no $a~ priori$ best $E_\\mathrm{diss}$ minimizing growth model, we here present a tool, called the "centrality fingerprint," for probing the behavior of different growth models. The centrality fingerprints are comparisons of the current flow into/out of the network with the values of various centrality measures calculated at every step of the growth process. Finally, we discuss applications to the Maryland power grid.

  5. Central pontine myelinolysis.

    Science.gov (United States)

    Kiley, M A; King, M; Burns, R J

    1999-03-01

    Central pontine myelinolysis (CPM) was initially associated with alcoholism. Subsequently other factors, including rapid reversal of hyponatraemia and extreme serum hypoosmolality associated with severe burns, have been identified as other important factors in its pathogenesis. Extra-pontine lesions have also been described. CPM may be found at autopsy, either having been overlooked during life or as an incidental finding. Its precise incidence is not known but the ability to diagnose it during life has been helped by modern neuroimaging, particularly magnetic resonance imaging (MRI) of the brain stem. In the past the prognosis for CPM was thought to be invariably fatal. It is clear now that with the greater general awareness of the disorder and the ability to diagnose it during life that some degree of recovery is possible. However, the number who do recover and the degree of recovery is not known. We report a 40-year-old man who developed CPM presenting with quadriparesis and inability to speak and swallow. There were risk factors for CPM and the diagnosis was confirmed by MRI scanning. He made a complete recovery although he remains ataxic. We are reporting this case as we believe it is important to make clinicians aware of the potential for recovery of CPM. While no specific treatment has been shown to influence the degree and rate of recovery of the demyelination, the fact that the quadriplegia and bulbar paralysis can recover fully is of considerable importance. In particular, it means that when the diagnosis is made, complete and vigorous nursing and medical care is warranted. PMID:18639140

  6. Central nervous system tumors

    International Nuclear Information System (INIS)

    Central nervous system (CNS) tumors are relatively common in veterinary medicine, with most diagnoses occurring in the canine and feline species. Numerous tumor types from various cells or origins have been identified with the most common tumors being meningiomas and glial cell tumors. Radiation therapy is often used as an aid to control the clinical signs associated with these neoplasms. In general, these tumors have a very low metastatic potential, such that local control offers substantial benefit. Experience in veterinary radiation oncology would indicate that many patients benefit from radiation treatment. Current practice indicates the need for computed tomography or magnetic resonance imaging studies. These highly beneficial studies are used for diagnosis, treatment planning, and to monitor treatment response. Improvements in treatment planning and radiation delivered to the tumor, while sparing the normal tissues, should improve local control and decrease potential radiation related problems to the CNS. When possible, multiple fractions of 3 Gy or less should be used. The tolerance dose to the normal tissue with this fractionation schedule is 50 to 55 Gy. The most common and serious complications of radiation for CNS tumors is delayed radiation myelopathy and necrosis. Medical management of the patient during radiation therapy requires careful attention to anesthetic protocols, and medications to reduce intracranial pressure that is often elevated in these patients. Canine brain tumors have served as an experimental model to test numerous new treatments. Increased availability of advanced imaging modalities has spawned increased detection of these neoplasms. Early detection of these tumors with appropriate aggressive therapy should prove beneficial to many patients

  7. Dublin South Central (DSC)

    LENUS (Irish Health Repository)

    O'Gorman, Clodagh S M

    2010-12-01

    Children who appear healthy, even if they have one or more recognized cardiovascular risk factors, do not generally have outcomes of cardiovascular or other vascular disease during childhood. Historically, pediatric medicine has not aggressively screened for or treated cardiovascular risk factors in otherwise healthy children. However, studies such as the P-Day Study (Pathobiological Determinants of Atherosclerosis in Youth), and the Bogalusa Heart Study, indicate that healthy children at remarkably young ages can have evidence of significant atherosclerosis. With the increasing prevalence of pediatric obesity, can we expect more health problems related to the consequences of pediatric dyslipidemia, hypertriglyceridemia, and atherosclerosis in the future? For many years, medications have been available and used in adult populations to treat dyslipidemia. In recent years, reports of short-term safety of some of these medications in children have been published. However, none of these studies have detailed long-term follow-up, and therefore none have described potential late side-effects of early cholesterol-lowering therapy, or potential benefits in terms of reduction of or delay in cardiovascular or other vascular end-points. In 2007, the American Heart Association published a scientific statement on the use of cholesterol-lowering therapy in pediatric patients. In this review paper, we discuss some of the current literature on cholesterol-lowering therapy in children, including the statins that are currently available for use in children, and some of the cautions with using these and other cholesterol-lowering medications. A central tenet of this review is that medications are not a substitute for dietary and lifestyle interventions, and that even in children on cholesterol-lowering medications, physicians should take every opportunity to encourage children and their parents to make healthy diet and lifestyle choices.

  8. y Banca Central

    Directory of Open Access Journals (Sweden)

    Ángel García Banchs

    2008-01-01

    Full Text Available Las teorías monetarias modernas, ortodoxas y heterodoxas, han pasado por alto el hecho de que posterior a la Segunda Guerra Mundial el mundo quedó dividido entre economías emisoras y receptoras de reservas, pasando el sistema monetario internacional desde entonces a ser completamente asimétrico. De allí que, desde el punto de vista teórico, señalemos la necesidad de tomar en cuenta si las economías emiten o no una moneda de reserva internacional, pues ello explicaría la existencia de diversas prácticas monetarias a nivel mundial. Este trabajo propone, y calcula, indicadores basados en datos provenientes de los balances de activos y pasivos de quince bancos centrales pertenecientes a Norteamérica, Suramérica, Europa y Asia. Los hallazgos con respecto a las diversas estructuras de activos y pasivos confirman la hipótesis acerca de la presencia de tales asimetrías. Se infiere en consecuencia que la política monetaria es menos flexible pero más influyente en las economías receptoras de reservas, y a la vez más flexible pero menos influyente en las economías emisoras. En pocas palabras, la exogeneidad de la tasa de interés de corto plazo es más débil en el caso de las economías receptoras de reservas las cuales se ven obligadas a acumular divisas y a procurar la estabilidad del tipo de cambio, debido a que sus monedas locales no son aceptadas en el exterior. Así, aunque la oferta crediticia es endógena en esas economías, las mismas no han sido capaces de librarse aún de la necesidad de mantener reservas monetarias en divisas extranjeras

  9. Central cooling: absorptive chillers

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J.E.

    1977-08-01

    This technology evaluation covers commercially available single-effect, lithium-bromide absorption chillers ranging in nominal cooling capacities of 3 to 1,660 tons and double-effect lithium-bromide chillers from 385 to 1,060 tons. The nominal COP measured at operating conditions of 12 psig input steam for the single-effect machine, 85/sup 0/ entering condenser water, and 44/sup 0/F exiting chilled-water, ranges from 0.6 to 0.65. The nominal COP for the double-effect machine varies from 1.0 to 1.15 with 144 psig entering steam. Data are provided to estimate absorption-chiller performance at off-nominal operating conditions. The part-load performance curves along with cost estimating functions help the system design engineer select absorption equipment for a particular application based on life-cycle costs. Several suggestions are offered which may be useful for interfacing an absorption chiller with the remaining Integrated Community Energy System. The ammonia-water absorption chillers are not considered to be readily available technology for ICES application; therefore, performance and cost data on them are not included in this evaluation.

  10. The Centralized Management and Clinical Application of Ventilators in Modern Hospital%现代医院呼吸机的集中管理与临床应用

    Institute of Scientific and Technical Information of China (English)

    何莺; 邢素美; 夏文俊

    2011-01-01

    目的 探讨现代医院呼吸机的集中管理模式及在临床中的推广应用.方法 观察、总结、分析近3年195例机械通气患者呼吸机集中管理的效果.结果 集中专人负责呼吸机的保管、供应、调试、保养、维护、消毒及故障排除,195例机械通气患者虽遇到各类报警950例,但由于发现及时、处理得当,均未对患者造成重大影响,呼吸机的完好率及使用率均达百分之百.结论 加强现代医院呼吸机的集中科学管理,培养造就一支高素质的专业人才队伍,将显著提高呼吸机的使用率和重症患者救治的成功率.%Objective To investigate the centralized management mode and clinical promotion of ventilators in modern hospitals.Methods 0bserved,9ummarized,and analyzed the centralized ventilators management effects of 195 patients with mechanical ventilation.Results Set persons specially designated for the jobs of storage, supply, debugging, maintenance, protection, disinfection and troubleshooting. 195 cases of patients with mechanical ventilation encountered 950 cases of various types of alarm,because of dealing with these problems timely and properly ,there was no significant loss on the patients, and the rate of the ventilators in good condition and urilization reached 100 percent.Conclsion By strengthening the centralized modern hospital ventilator scientific management,training and fostering a high quality team of professionals,we will significantly improve the utilization rate of the ventilator and the success rate rescue of critical patients.

  11. Central bank independence and ageing

    OpenAIRE

    Farvaque, Etienne; Héricourt, Jérôme; Lagadec, Gaël

    2008-01-01

    We contrast the influence of demography and central bank independence on inflation. The recent demographic trends in developed countries are shown to weight more on inflation than central bank independence, while the contrary stands for the period from 1960 to 1979.

  12. The Mediterranean fruit fly in Central America

    International Nuclear Information System (INIS)

    Various methods of controlling the medfly are available and include the use of insecticides, bait sprays and the sterile insect technique (SIT). Each of these control strategies may be used alone or in sequence. With regard to the application of the SIT, the Joint FAO/IAEA Division of Atomic Energy in Food and Agriculture through its Insect and Pest Control Section and Entomology Laboratory is in an excellent position to assist in containing the medfly in Central America. For the past 12 years, the laboratory has participated in all phases of medfly control by sterile insect releases in various climates. This involvement has included planning of medfly campaigns, development of pre-release techniques (bait spraying, trapping, etc.) and shipment and release of sterilized medflies. Small-scale field tests utilizing the SIT have been carried out by nine countries: Italy (Procida, Capri), Spain, Cyprus, Israel, Tunisia, Peru, Panama, Costa Rica and Nicaragua. Other field projects presently being counselled and serviced are located in Argentina, Venezuela and the Canary Islands. The research and development that are still needed to effectively stabilize and gain control of the medfly situation in Central America include: The development and use of effective quarantine procedures in various countries; Development of effective conventional medfly control procedures under the conditions found in Central America; Development of methods to determine the geographic origin of medflies introduced into new areas; Medfly mass production (viz. all aspects of rearing Central American strains); Assessing the performance (competitiveness, etc.) of various strains; Logistics, including the development of systems for releasing pre-adult stages; Genetic rearing methods: developmental research in this area is particularly promising since the preferential production of males would allow considerable savings in the rearing costs of medflies for release; Development of adequate surveillance

  13. SQUARE AND RHOMBUS CENTRAL CONFIGURATIONS

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    In this paper, we consider the flat central configurations of bodies using the characteristic set method. We completely solve two special cases of four planets, namely,the square and the rhombus. For the square case, we obtain that a square is a central configuration only in the case where the masses are equal and there exactly are two different square central configurations determined by the mass and the angular velocity; for the rhombus case, we obtain that if a rhombus is a central configuration, then the masses of the diagonal vertices must be equal. Furthermore, there are two or three or four different rhombus central configurations determined by the masses and the angular velocity.

  14. Central control of body temperature.

    Science.gov (United States)

    Morrison, Shaun F

    2016-01-01

    Central neural circuits orchestrate the behavioral and autonomic repertoire that maintains body temperature during environmental temperature challenges and alters body temperature during the inflammatory response and behavioral states and in response to declining energy homeostasis. This review summarizes the central nervous system circuit mechanisms controlling the principal thermoeffectors for body temperature regulation: cutaneous vasoconstriction regulating heat loss and shivering and brown adipose tissue for thermogenesis. The activation of these thermoeffectors is regulated by parallel but distinct efferent pathways within the central nervous system that share a common peripheral thermal sensory input. The model for the neural circuit mechanism underlying central thermoregulatory control provides a useful platform for further understanding of the functional organization of central thermoregulation, for elucidating the hypothalamic circuitry and neurotransmitters involved in body temperature regulation, and for the discovery of novel therapeutic approaches to modulating body temperature and energy homeostasis. PMID:27239289

  15. 低压集抄智能化闭环管理模式的研究与应用%Research and Application of Intelligent Closed-loop Management Mode of Low-voltage Centralized Meter-reading

    Institute of Scientific and Technical Information of China (English)

    庄杰; 徐川子; 王晶

    2015-01-01

    基于低压集抄智能化闭环管理模式实现了对采集器关联和电能表轮换的有效管控,同时结合数据库技术,利用掌机直接将现场安装或维修的原始清单以电子稿形式导出,以便对安装或维修数量进行核对,确保表计、采集器的领、配、用数量一致,避免资产流失,实现资产的精细化管理。该管理模式全面实施后,真正实现了低压集抄系统工单下装、派工、安装以及故障处理信息上装的全过程无纸化智能作业,提高了工作效率。%The basic intelligent closed-loop management mode of low-voltage centralized meter-reading effec-tively controls the collector correlation and the energy meter alternation. Combining with database technology, it can export the site installation original lists directly in the form of electronic version using a handheld con-sole to check the quantity of installation or maintenance quickly and ensure the uniform number of collection, distribution as well as use of the meters and collectors to avoid assets loss and implement refined management of assets. Since the management mode is fully implemented, it really realizes the whole process intelligent work including work orders downloading, dispatching, installation and troubleshooting information uploading of the low-voltage centralized meter-reading system and improves the work efficiency.

  16. Centralized coke gasification study

    Energy Technology Data Exchange (ETDEWEB)

    du Plessis, Duke [Alberta Innovates (Canada); Pietrusik, Debbie [Alberta Finance and Enterprise (Canada)

    2011-07-01

    By the year 2020 Alberta will produce 3 million barrels of bitumen per day. Refining bitumen yields several by-products such as petroleum coke and off-gasses. These products can be further utilized as a low cost feedstock for additional applications to increase revenue. Alberta currently has the largest amount of coke stockpiled in the world. The presentation explores what is the most profitable way to use this coke and what future technologies would improve the economic and environmental impact of the process. The development of methane and hydrogen becomes competitive at intermediate gas and oil prices. The next generation of gasification technologies is going to be cheaper, efficient and much smaller. Pilot projects have shown positive results. Economies of scale can be reached simply by only 20-30% of annual coke production. The high cost of the current technology is creating the biggest challenge but new technologies and process innovations have the potential to drive down cost.

  17. The ATLAS central solenoid

    CERN Document Server

    Yamamoto, A; Ruber, R; Doi, Y; Haruyama, T; Haug, F; ten Kate, H; Kawai, M; Kondo, T; Kondo, Y; Metselaar, J; Mizumaki, S; Olesen, G; Pavlov, O; Ravat, S; Sbrissa, E; Tanaka, K; Taylor, T; Yamaoka, H

    2008-01-01

    The ATLAS detector at the CERN LHC is equipped with a superconducting magnet system consisting of three large toroids and a solenoid. The 2.3 m diameter, 5.3 m long solenoid is located at the heart of the experiment where it provides a 2 T field for spectrometry of the particles emanating from the interaction of the counter-rotating beams of hadrons. As the electromagnetic calorimeter of the experiment is situated outside the solenoid, the coil must be as transparent as possible to traversing particles. The magnet, which was designed at KEK, incorporates progress in technology coming from the development of previous solenoids of this type, in particular that of a new type of reinforced superconductor addressing the requirement of transparency. Special attention has been paid to ensuring reliability and ease of operation of the magnet, through the application of sufficiently conservative guidelines for the mechanical and electrical design, stringent testing during manufacture, and a comprehensive commissioning...

  18. Central Limit Theorem for Nonlinear Hawkes Processes

    CERN Document Server

    Zhu, Lingjiong

    2012-01-01

    Hawkes process is a self-exciting point process with clustering effect whose jump rate depends on its entire past history. It has wide applications in neuroscience, finance and many other fields. Linear Hawkes process has an immigration-birth representation and can be computed more or less explicitly. It has been extensively studied in the past and the limit theorems are well understood. On the contrary, nonlinear Hawkes process lacks the immigration-birth representation and is much harder to analyze. In this paper, we obtain a functional central limit theorem for nonlinear Hawkes process.

  19. Centralized versus Decentralized Information Systems

    Science.gov (United States)

    Hugoson, Mats-Åke

    This paper brings into question whether information systems should be centralized or decentralized in order to provide greater support for different business processes. During the last century companies and organizations have used different approaches for centralization and decentralization; a simple answer to the question does not exist. This paper provides a survey of the evolution of centralized and decentralized approaches, mainly in a Nordic perspective. Based on critical reflections on the situation in the end of the century we can discuss what we can learn from history to achieve alignment between centralized and decentralized systems and the business structure. The conclusion is that theories, management and practice for decisions on centralization or decentralization of information systems must be improved. A conscious management and control of centralization /decentralization of IT support is a vital question in the company or the organization, and this is not a task that can be handled only by IT-specialists. There is a need for business oriented IT management of centralization/decentralization.

  20. Betweenness centrality profiles in trees

    CERN Document Server

    Fish, Benjamin; Turan, Gyorgy

    2016-01-01

    Betweenness centrality of a vertex in a graph measures the fraction of shortest paths going through the vertex. This is a basic notion for determining the importance of a vertex in a network. The k-betweenness centrality of a vertex is defined similarly, but only considers shortest paths of length at most k. The sequence of k-betweenness centralities for all possible values of k forms the betweenness centrality profile of a vertex. We study properties of betweenness centrality profiles in trees. We show that for scale-free random trees, for fixed k, the expectation of k-betweenness centrality strictly decreases as the index of the vertex increases. We also analyze worst-case properties of profiles in terms of the distance of profiles from being monotone, and the number of times pairs of profiles can cross. This is related to whether k-betweenness centrality, for small values of k, may be used instead of having to consider all shortest paths. Bounds are given that are optimal in order of magnitude. We also pre...

  1. Central chemoreceptors: locations and functions.

    Science.gov (United States)

    Nattie, Eugene; Li, Aihua

    2012-01-01

    Central chemoreception traditionally refers to a change in ventilation attributable to changes in CO2/H(+) detected within the brain. Interest in central chemoreception has grown substantially since the previous Handbook of Physiology published in 1986. Initially, central chemoreception was localized to areas on the ventral medullary surface, a hypothesis complemented by the recent identification of neurons with specific phenotypes near one of these areas as putative chemoreceptor cells. However, there is substantial evidence that many sites participate in central chemoreception some located at a distance from the ventral medulla. Functionally, central chemoreception, via the sensing of brain interstitial fluid H(+), serves to detect and integrate information on (i) alveolar ventilation (arterial PCO2), (ii) brain blood flow and metabolism, and (iii) acid-base balance, and, in response, can affect breathing, airway resistance, blood pressure (sympathetic tone), and arousal. In addition, central chemoreception provides a tonic "drive" (source of excitation) at the normal, baseline PCO2 level that maintains a degree of functional connectivity among brainstem respiratory neurons necessary to produce eupneic breathing. Central chemoreception responds to small variations in PCO2 to regulate normal gas exchange and to large changes in PCO2 to minimize acid-base changes. Central chemoreceptor sites vary in function with sex and with development. From an evolutionary perspective, central chemoreception grew out of the demands posed by air versus water breathing, homeothermy, sleep, optimization of the work of breathing with the "ideal" arterial PCO2, and the maintenance of the appropriate pH at 37°C for optimal protein structure and function.

  2. Central European gas market perspectives

    International Nuclear Information System (INIS)

    This presentation deals with (1) Definition of the Central European market, (2) Factors driving up consumption of natural gas in Central and Eastern Europe, (3) Role of natural gas in regional energy consumption, (4) Position of natural gas in individual country markets, (5) Future sources of imported natural gas into the region. The Central European market are the eleven countries Albania, Bulgaria, Croatia, Czech Republic, Hungary, Macedonia, Poland, Romania, Serbia and Montenegro, Slovakia, and Slovenia, with a total population of 121 million. This market is comparable to combined France and Italy in terms of population, but only 30% of its size in terms of GDP

  3. Centralized digital control of accelerators

    International Nuclear Information System (INIS)

    In contrasting the title of this paper with a second paper to be presented at this conference entitled Distributed Digital Control of Accelerators, a potential reader might be led to believe that this paper will focus on systems whose computing intelligence is centered in one or more computers in a centralized location. Instead, this paper will describe the architectural evolution of SLAC's computer based accelerator control systems with respect to the distribution of their intelligence. However, the use of the word centralized in the title is appropriate because these systems are based on the use of centralized large and computationally powerful processors that are typically supported by networks of smaller distributed processors

  4. Clinical Application of Two kinds of Central Vein Catheterization in Hemodialysis%两种深静脉置管方式在血液透析中的临床应用

    Institute of Scientific and Technical Information of China (English)

    刘林; 王晓红; 吴桂明

    2012-01-01

    目的 探讨寻找安全有效的血液透析中心静脉置管方式.方法 回顾性分析我院245例中心静脉置管术,颈内静脉置管171例,股静脉置管74例,其中盲穿置管169例,彩超定点引导穿刺置管76例.分析两种置管方式临床并发症的发生率及处理方法.结果 盲穿患者近期并发症中误伤动脉6例(3.6%),局部血肿4例(2.4%),渗血3例(1.8%),误伤胸导管1例(0.6%),气胸1例(0.6%).影超定点引导下穿刺置管成功69例,未发生近期并发症.两种方式比较(P<0.05).结论 彩超定点引导中心静脉置管是一种安全有效的方法,可在临床推广应用.%Objective To explore and find the safe and effective method of central vein catheterization for hemodialysis patients. Methods We analyzed 245 hemodialysis patients using central vein catheterization retrospectively. 171 internal jugular venous catheterizations and 74 femoral venous catheterization were included in the study. Two methods were performed: blind catheterization in 169 cases and catheterization by color Doppler ultrasonography guidance in 76 cases. Complications and management of the two methods were analyzed with P<0. 05. Results In the 169 cases using blind catheterization. complications included misplacement into arteries in 6(3. 6%), local hematoma in 4(2. 4%), local bleeding in 3(1. 8%). misplacement into thoracic duct(0. 6%), pneumothorax in 1(0.6%). No complications were found in 76 cases by color Doppler ultrasonography guidance. Conclusion Catheterization by color Doppler ultrasonography guidance is a safe and effective method.

  5. 案例教学法在中枢神经解剖学教学中的应用%Application of case method in central nervous system anatomy teaching

    Institute of Scientific and Technical Information of China (English)

    谭刚; 覃能武; 王振富

    2009-01-01

    Objective To reinforce the training of medical students'clinical thinking ability in the stage of learning basic medicine.Methods Case method was introduced into central nervous system anatomy teaching and questionnaires was made accordingly.Results Answers to questionnaires revealed that it had remarkable effects on improving students'ability of clinical logical thinking,inductive analysis,combining basic theoretical knowledge with clinical practice and self-learning,etc.Conclusions Case method was conducive to students'understanding and absorption of knowledge,and could stimulate students'enthusiasm and initiative in learning central nervous system anatomy.It was also effective in realizing the two-way infiltration of basic medical theories and clinical knowledge,thus to enable the students to initially set up the concept of disease and strengthen the cultivation of students'clinical thinking ability.%目的 在基础医学学习阶段加强医学生临床思维能力培养.方法 将案例教学法引入中枢神经解剖学教学中,设计问卷就教学效果对学生进行调查.结果 案例教学法对提高学生的临床逻辑思维能力、归纳分析能力、基础理论知识与临床实践相结合能力、自学能力等有着较好的效果.结论 运用案例教学法有利于学生对知识的理解和吸收,能够激发学生学习中枢神经解剖学的积极性和主动性,可以有效地实现医学基础理论与临床知识的"双向渗透",使学生初步建立起疾病的概念,从而加强其临床思维能力的培养.

  6. 浅谈网上银行在地勘单位资金集中管理中的应用%Discussion on Application of Internet Banking to the Centralized Management of Funds in Geological Prospecting Units

    Institute of Scientific and Technical Information of China (English)

    周红涛

    2014-01-01

    Internet banking has provide new ideas and ways for ensuring safe and efficient centralized management of funds in geological prospecting units. This means that through internet banking we have achieved bank-enterprise interconnection. By using internet technical operation, we have changed the traditional way of banking ifnancial services. By adopting the pattern of “tree group accounts”we have realized the centralized management. This paper goes on to look at that through internet banking the fund supervision that geological prospecting units performed to their branches has been enhanced. As a result, the efifciency of accounting work and the ifnancial management level have been increased, thus reducing the ifnancial costs. On this basis, this paper points out that in order to reduce the external risk of online banking, we must choose safe and reliable correspondent banks with mature technology. We must choose secure network and authentication medium so as to ensure a secured login. At the same time, a standard operational process and reasonable operation permission should be established so as to ensure the safe usage of online banking. In addition, strict internal accounting control system should be formulated so as to guard against online banking risk.%网上银行为确保地勘单位资金集中管理的安全高效提供了新思路和途径。通过网上银行实现了“银企互联”;利用Internet技术操作,改变了传统的银行金融服务方式;采用“树状集团开户”的模式,实现资金的集中管理。网上银行加强了地勘单位对各分支机构的资金监管、提高了会计工作效率和财务管理水平、降低了财务费用。选择安全可靠、技术成熟的代理银行,降低网上银行外部风险;选择安全的网络及认证介质,保证网上银行安全登录;建立规范的操作流程和合理的操作权限,保证网上银行安全使用;制定严密的内部会计控制制度

  7. Demographic tensions in Central America.

    Science.gov (United States)

    1986-08-01

    This discussion of Central America focuses on the rapid growth of its population, its stagnating economy, and those countries that are socioeconomically advanced. Between 1950-85 the population of Central America tripled, from 9.1 million to 26. 4 million, due to marked mortality declines and the absence of off-setting fertility declines. The distribution of Central Americas's growing populations sets its population growth apart from that of other developing regions. Currently, almost half of all Central Americans live in cities. Although the average growth rate for Central American countries has fallen and is expected to drop further, the decline does not counterbalance the effect of the absolute rise in population numbers. The average annual growth rate of more than 3% annually in the 1960s fell to about 2.6% in recent years, but this decline is due primarily to socioeconomically advanced Costa Rica and Panama. Central America's age structure further complicates the population crisis. About 43% of Central Americans are under the age of 15. When the increasingly larger young population group enters it reproductive years, the potential for future growth (albeit the falling rate of population increase) is unparalleled. UN population projections show the region's population at 40 million by the year 2000. The 1973 oil crisis began a downward spiral for the buoyant post World War II Central American economy. Between 1950-79, real per capita income growth in Central America doubled, with Central American economies growing an average of 5.3% annually. By the early 1980s, overseas markets of the trade-dependent countries of Central America had dried up due to protectionism abroad and slumping basic commodity prices. These and other factors plunged Central America into its current economic malaise of falling real per capita income, rising unemployment, curtailed export led economic growth, and a rising cost of living. In general, economic growth in Central America

  8. GC-MS/MS survey of collision-induced dissociation of tert-butyldimethylsilyl-derivatized amino acids and its application to (13)C-metabolic flux analysis of Escherichia coli central metabolism.

    Science.gov (United States)

    Okahashi, Nobuyuki; Kawana, Shuichi; Iida, Junko; Shimizu, Hiroshi; Matsuda, Fumio

    2016-09-01

    Stable isotope labeling experiments using mass spectrometry have been employed to investigate carbon flow levels (metabolic flux) in mammalian, plant, and microbial cells. To achieve a more precise (13)C-metabolic flux analysis ((13)C-MFA), novel fragmentations of tert-butyldimethylsilyl (TBDMS)-amino acids were investigated by gas chromatography-tandem mass spectrometry (GC-MS/MS). The product ion scan analyses of 15 TBDMS-amino acids revealed 24 novel fragment ions. The amino acid-derived carbons included in the five fragment ions were identified by the analyses of (13)C-labeled authentic standards. The identification of the fragment ion at m/z 170 indicated that the isotopic abundance of S-methyl carbon in methionine could be determined from the cleavage of C5 in the precursor of [M-159](+) (m/z 218). It was also confirmed that the precision of (13)C-MFA in Escherichia coli central carbon metabolism could be improved by introducing (13)C-labeling data derived from novel fragmentations. Graphical Abstract Novel collision-induced dissociation fragmentations of tert-butyldimethylsilyl amino acids were investigated and identified by GC-MS/MS.

  9. The Application of Box–Cox Transformation to Determine the Standardised Precipitation Index (SPI, the Standardised Discharge Index (SDI and to Identify Drought Events: Case Study in Eastern Kujawy (Central Poland

    Directory of Open Access Journals (Sweden)

    Bartczak Arkadiusz

    2014-10-01

    Full Text Available The article presents the results of research into the transformation of series of hydro-meteorological data for determining dry periods with the Standardised Precipitation Index (SPI and the Standardised Discharge Index (SDI. Time series from eight precipitation stations and five series of river discharge data in Eastern Kujawy (central Poland were analysed for 1951–2010. The frequency distribution of the series for their convergence with the normal distribution was tested with the Shapiro–Wilk test and homogeneity with the Bartlett's test. The transformation of the series was done with the Box–Cox technique, which made it possible to homogenise the series in terms of variance. In Poland, the technique has never been used to determine the SPI. After the transformation the distributions of virtually all series complied with the normal distribution and were homogeneous. Moreover, a statistically significant correlation between the δ transformation parameter and the skewness of the series of monthly precipitation was observed. It was similar for the series of mean monthly discharges in the winter half-year and the hydrological year. The analysis indicates an alternate occurrence of dry and wet periods both in case of precipitation and run-offs. Drought periods coincided with low flow periods. Thus, the fluctuations tend to affect the development of agriculture more than long-term ones.

  10. 仅有角度测量跟踪问题中的中央差分算法改进%Improved Central Difference Kalman Filter with Applications to Bearings-only Tracking

    Institute of Scientific and Technical Information of China (English)

    苏航; 汪语哲; 张汝波; 刘冠群

    2014-01-01

    为解决仅有角度测量的目标跟踪系统初始误差大、可观性弱、精确实时跟踪困难等问题,研究了一种改进中央差分卡尔曼滤波算法。仿真结果表明,同传统估计方法相比,该算法精度高,收敛速度快,且计算量适中,易于在实战中实时跟踪。%Under many circumstances, bearings-only target tracking was characterized by large initial estimation error and weak observability, making it difficult for precise real time tracking. In order to solve such problem, an improved central difference Kalman Filter was investigated in this paper. Simulation results showed that compared to traditional tracking filter, the proposed method guaranteed higher estimation accuracy and faster convergence speed, and moderate level of computation made it easy for real time tracking in battlefield case.

  11. PBL在人体中枢神经解剖学教学中的应用%Application of problem-based learning in the teaching practice of human central nervous system anatomy

    Institute of Scientific and Technical Information of China (English)

    欧阳长杰; 曲德伟; 王德广

    2012-01-01

    This paper introduced the scheme,form and measures of implementing problem-based learning in the teaching practice of human central nervous system anatomy.This paper discussed on the depth and scope of the issue,how to mobilize the enthusiasm of the students in the process of discussion,how to be conscious of curriculum knowledge system and logic in the teaching process,how to make students expose to clinical at early stage,how to provide corresponding assessment methods and other aspects of the practice in an aim to help peers to improve the teaching practice.%介绍在人体中枢神经解剖学课程教学中实施以问题为基础的学习(problem-based learning,PBL)的具体方案、形式和措施.并探讨拟定讨论问题的深度与范围,在学生讨论过程中如何调动其积极性,教师在教学过程中如何注意课程知识的系统性和逻辑性,如何让学生早期接触临床,如何配套相应的考核方式等.

  12. The Central Trigger Processor (CTP)

    CERN Multimedia

    Franchini, Matteo

    2016-01-01

    The Central Trigger Processor (CTP) receives trigger information from the calorimeter and muon trigger processors, as well as from other sources of trigger. It makes the Level-1 decision (L1A) based on a trigger menu.

  13. Audit Committees in Central Banks

    OpenAIRE

    Kenneth Sullivan; Marie-Therese Camilleri; Tonny Lybek

    2007-01-01

    This paper reviews the tasks and design of audit committees, increasingly recommended as a way to strengthen financial accountability and good central bank governance. It outlines the motivations for the establishment of audit committees in commercial corporations and public sector entities, and explains how audit committees interact with other governance bodies within a central bank. The paper focuses on the functions of an audit committee, since the terminology of the governance structure i...

  14. CENTRAL PLATEAU REMEDIATION OPTIMIZATION STUDY

    Energy Technology Data Exchange (ETDEWEB)

    BERGMAN, T. B.; STEFANSKI, L. D.; SEELEY, P. N.; ZINSLI, L. C.; CUSACK, L. J.

    2012-09-19

    THE CENTRAL PLATEAU REMEDIATION OPTIMIZATION STUDY WAS CONDUCTED TO DEVELOP AN OPTIMAL SEQUENCE OF REMEDIATION ACTIVITIES IMPLEMENTING THE CERCLA DECISION ON THE CENTRAL PLATEAU. THE STUDY DEFINES A SEQUENCE OF ACTIVITIES THAT RESULT IN AN EFFECTIVE USE OF RESOURCES FROM A STRATEGIC PERSPECTIVE WHEN CONSIDERING EQUIPMENT PROCUREMENT AND STAGING, WORKFORCE MOBILIZATION/DEMOBILIZATION, WORKFORCE LEVELING, WORKFORCE SKILL-MIX, AND OTHER REMEDIATION/DISPOSITION PROJECT EXECUTION PARAMETERS.

  15. Rogoff's 'Conservative' Central Banker Restored

    OpenAIRE

    Herrendorf, Berthold; Lockwood, Ben

    1996-01-01

    This paper shows that delegation of monetary policy to a weight-conservative central banker is optimal, although the government can also use an inflation contract, an employment target, an inflation target, or any combination of these, to control the central banker. The key feature of our model is a stochastic inflation bias, arising when wage-setters receive some information about a supply shock prior to signing nominal wage contracts. Weight-conservatism is shown to be desirable if the stoc...

  16. Congenital nystagmus and central hypothyroidism

    OpenAIRE

    Reynaert, Nele; Braat, Elke; de Zegher, Francis

    2015-01-01

    We observed a male newborn with bilateral nystagmus and central hypothyroidism without hypoprolactinemia due to a deletion of chromosome band Xq26.1q26.2, containing FRMD7 and IGSF1. These two loss-of function mutations are known to cause, respectively, congenital nystagmus and the ensemble of central hypothyroidism, hypoprolactinemia and testicular enlargement. These latter two features may not yet be present in early life.

  17. Application of MAGIC to Lake Redó (Central Pyrenees: an assessment of the effects of possible climate driven changes in atmospheric precipitation, base cation deposition, and weathering rates on lake water chemistry

    Directory of Open Access Journals (Sweden)

    Marc VENTURA

    2004-02-01

    Full Text Available The process-oriented catchment-scale model MAGIC was used to simulate water chemistry at Lake Redó, a high mountain lake in the Central Pyrenees, Spain. Data on lakewater and atmospheric deposition chemistry for the period 1984-1998 were used to calibrate the model, which was then used to reconstruct past and to provide forecasts for three hypothetical future scenarios of deposition. Forecast scenarios considered several combinations of changes in S and N deposition due to abatement strategies, and in base cation deposition due to climate-induced changes in air-mass trajectories from northern Africa. Scenario 1 assumed constant deposition of base cations at the present level plus the expected decrease in S and N deposition resulting from reduced emissions; scenario 2 (best case assumed an increase in base cation deposition plus the same decrease in S and N deposition as in scenario 1; scenario 3 (worst case assumed a decrease in base cation deposition plus no decrease in S and N deposition. The hindcast indicated that during the past 140-year period changes in lake water chemistry have been significant for a remote mountain catchment, although no substantial acidification has occurred. In this regard Lake Redó can be described as a "non-sensitive lake" maintaining a reference condition. The forecasts indicated changes that do not affect this status, but the trends, even if slight, were different between scenarios. A slight decline in the surface water ANC is predicted by Scenario 3. The N budget indicates an unusually low retention in the catchment, which may result in enhanced sensitivity to further increased N deposition. Some of the discrepancy between modelled and measured Ca2+ in lake water during 1984-98 could be explained by changes in rainfall amounts and by increased weathering rates due to increases in air temperature.

  18. Application Analysis on Antibacterials in Children with Central Nervous System Infection%中枢神经系统感染患儿抗菌药物应用分析

    Institute of Scientific and Technical Information of China (English)

    王梅; 陶胜岩; 张强

    2011-01-01

    目的 了解我院近年儿科中枢神经系统感染的发病情况及抗菌药物应用的情况.方法 回顾调查分析儿科2008~2009年度中枢神经系统感染出院331例的病例,统计患儿年龄、病原学、抗菌药物种类、用量用法、用药时间等.结果 我院中枢神经系统感染患儿以病毒感染最为常见.抗菌药物主要应用三代头孢菌素、青霉素类.结论 我院中枢神经系统感染患儿抗菌药物应用基本合理,需要采取措施进一步提高病原菌送检率.%Objective To investigate the incidence and the utilization of antibacterials in children with central nervous system (CNS) infection in Provincial Hospital Affiliated to Shandong University. Methods A total of 331 medical records of children with CNS infection who were discharged from 2008 to 2009 were surveyed for a statistical analysis in respect of patient's age, etiology and drug sorts, usage, treatment period, etc. Results The viral infection was most common of 331 patients. The most frequently used antibacterials were the third generation cephalosporins and penicillins. Conclusion The usage of antibacterials in children with CNS infection is rational on the whole. The measures need to be taken to improve the detection rate of pathogenic bacteria.

  19. The application of terrestrial laser scanner and SfM photogrammetry in measuring erosion and deposition processes in two opposite slopes in a humid badlands area (central Spanish Pyrenees)

    Science.gov (United States)

    Nadal-Romero, E.; Revuelto, J.; Errea, P.; López-Moreno, J. I.

    2015-08-01

    Erosion and deposition processes in badland areas are usually estimated using traditional observations of topographic changes, measured by erosion pins or profile metres (invasive techniques). In recent times, remote-sensing techniques (non-invasive) have been routinely applied in geomorphology studies, especially in erosion studies. These techniques provide the opportunity to build high-resolution topographic models at centimetre accuracy. By comparing different 3-D point clouds of the same area, obtained at different time intervals, the variations in the terrain and temporal dynamics can be analysed. The aim of this study is to assess and compare the functioning of terrestrial laser scanner (TLS, RIEGL LPM-321) and structure-from-motion photogrammetry (SfM) techniques (Camera FUJIFILM, Finepix x100 and software PhotoScan by AgiSoft) to evaluate erosion and deposition processes in two opposite slopes in a humid badlands area in the central Spanish Pyrenees. Results showed that TLS data sets and SfM photogrammetry techniques provide new opportunities in geomorphological erosion studies. The data we recorded over 1 year demonstrated that north-facing slopes experienced more intense and faster changing geomorphological dynamics than south-facing slopes as well as the highest erosion rates. Different seasonal processes were observed, with the highest topographic differences observed during winter periods and the high-intensity rainfalls in summer. While TLS provided the highest accuracy models, SfM photogrammetry was still a faster methodology in the field and precise at short distances. Both techniques present advantages and disadvantages, and do not require direct contact with the soil and thus prevent the usual surface disturbance of traditional and invasive methods.

  20. Construction and Application of Centralized Control Performance Management System in Thermal Power Plant%火电厂集控绩效管理体系建设与应用

    Institute of Scientific and Technical Information of China (English)

    翟守臣

    2015-01-01

    In order to accelerate the revolution of energy production and consumption, further improve the efficient and cleaning development level of coal-fired electricity, and carry out more strict environmental standards, thermal power enterprises should start from the management and reconstruction of equipment, and achieve further efficiencies in terms of optimizing operation adjustment. And its means is to strengthen the management and seek effectiveness from management, set up the performance management system to realize internal potential of centralized control operation personnel, enhance the sense of responsibility, standardize the operators' behaviors, and improve operation skill levels by motivating employees to achieve the goal of reducing cost and increasing efficiency based on the optimization and adjustment.%为加快推动能源生产和消费革命,进一步提升煤电高效清洁发展水平,推行更严格能效环保标准,火电企业不仅要从设备治理和改造入手,还要在优化运行调整方面实现进一步挖潜增效,其手段就是强化管理,向管理要效益。建立运行人员绩效管理体系,实现对集控运行人员规范化、标准化、数据化综合评价的管理模式,激发集控运行人员的内在潜能,提高责任心和责任意识,规范员工的作业行为,通过激励员工努力提升运行操作技能水平,在优化调整上达到降本增效的根本目的。

  1. Determination of 222Rn in water by absorption in polydimethylsiloxane mixed with activated carbon and gamma-ray spectrometry: An example application in the radon budget of Paterno submerged sinkhole (Central Italy)

    International Nuclear Information System (INIS)

    Highlights: ► Polydimethylsiloxane and Activated Carbon were used as passive gas accumulator. ► Water-impermeable properties of PDMS combine with adsorptive properties of AC. ► PDMS–AC accumulators can be used to study 222Rn in water. ► Measured 222Rn specific activity in PDMS–AC matches the theoretical results. ► We used PDMS–AC in the radon budget of a submerged sinkhole. - Abstract: Passive gas accumulators made of polydimethylsiloxane (PDMS) mixed with activated C (AC) were studied to measure their efficiency for sampling Rn in water. In this composite the water-impermeable properties of PDMS act synergistically with adsorptive properties of AC, even when the accumulators are immersed in water for many days. A series of tests where cylindrical shaped PDMS–AC disks were exposed to different 222Rn-enriched waters showed that measured 222Rn specific activity matches the theoretical results coming from the equation that describes the process of internal diffusion integrated with the Rn decay term. The linear relationship between 222Rn in water and the accumulation process in PDMS–AC, the influence of temperature and the different sensitivity of the composite and its components were also studied and discussed. The high Rn volumetric enrichment factor in PDMS–AC disks respect to water resulted in about 206: 1, so lowering detection limits for 222Rn in water to 20 Bq m−3 when the total activity of Rn progeny in disks is measured by high resolution gamma-ray spectrometry. The use of PDMS–AC accumulators was tested at the Paterno submerged sinkhole, in central Italy. This study allowed the production of a detailed synchronous vertical profile of the Rn content in the middle of the lake and to define the Rn balance by assessing the discharge rate of submerged springs and the average residence time of the lake water

  2. Core reactor simulation of the Central Laguna Verde (CLV) reactor in stationary state and an example of the application in the recharge options analysis of cycle 3; Simulacion del nucleo del reactor de la Central Laguna Verde (CLV) en estado estacionario y ejemplo de aplicacion en el analisis de alternativas de recarga del ciclo 3

    Energy Technology Data Exchange (ETDEWEB)

    Ocampo Mansilla, Hector; Francois Lacouture, Juan Luis; Blanco Lara, Jesus; Cortes Campos, Carlos Cristobal; Esquivias Montoya, Jesus; Esquivel Torres, Jose Luis; Martin del Campo Marquez, Cecilia [Instituto de Investigaciones Electricas, Cuernavaca (Mexico); Montes Tadeo, Jose Luis [Instituto Nacional de Investigaciones Nucleares (ININ), Salazar (Mexico); Sanchez Herrera, Luciano; Torres Alvarez, Carlos [Comision Federal de Electricidad (CFE), Mexico, D. F. (Mexico)

    1991-12-31

    The results are presented of a study requested by Comision Federal de Electricidad (CFE) for the analysis of Cycle 3, of Unit No. 1 of the Laguna Verde Nuclear Power Station (CLNV) and determine the burning effect impact, carried out with the starting tests and the operation of Cycles 1 and 2 on base of the cycle extension known as coastdown. The calculations were realized with the Code Package FMS for fuel managing, using the Code PRESTO-B that analyzes the reactor in detailed form in three dimensions an in stationary state. In the study the schemes of fraction of recharge proposed by General Electric (GE) were analyzed with the effect of cycle extension. The initial design value of 100 assemblies for Cycle 3, GE proposes to increase such fraction from 112 to 120 assemblies. This impacts the cost of the second recharge and the purpose of this investigation is to analyze options with higher fuel enrichment in U-235 to minimize the number of assemblies in this recharge. The analyses effected show that the designs proposed by GE do not fulfill the required energy proposed for the cycle, even using in the recharge only fuel with 3.03% of enrichment. It is proposed, likewise, the fuel enrichment up to 3.25% to satisfy the energy demand with a minimum of assemblies. [Espanol] Se presentan los resultados de un estudio solicitado por la Comision Federal de Electricidad (CFE) para analizar el ciclo 3, de la unidad 1 de la Central Laguna Verde (CLV), y determinar el impacto del efecto de quemado llevado a cabo con las pruebas de arranque y por la operacion de los ciclos 1 y 2 con base en la tecnica de alargamiento del ciclo conocida como coastdown1. Los calculos se realizaron con el paquete de codigos FMS para la administracion de combustible, usando el codigo PRESTO-B que analiza el reactor en forma detallada en tres dimensiones y en estado estacionario. Se analizaron en el estudio los esquemas de fraccion de recarga propuesta por la General Electric (GE) con el efecto de

  3. Central Facilities Area Sewage Lagoon Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Mark R. Cole

    2013-12-01

    The Central Facilities Area (CFA), located in Butte County, Idaho, at the Idaho National Laboratory has an existing wastewater system to collect and treat sanitary wastewater and non-contact cooling water from the facility. The existing treatment facility consists of three cells: Cell #1 has a surface area of 1.7 acres, Cell #2 has a surface area of 10.3 acres, and Cell #3 has a surface area of 0.5 acres. If flows exceed the evaporative capacity of the cells, wastewater is discharged to a 73.5-acre land application site that uses a center-pivot irrigation sprinkler system. As flows at CFA have decreased in recent years, the amount of wastewater discharged to the land application site has decreased from 13.64 million gallons in 2004 to no discharge in 2012 and 2013. In addition to the decreasing need for land application, approximately 7.7 MG of supplemental water was added to the system in 2013 to maintain a water level and prevent the clay soil liners in the cells from drying out and “cracking.” The Idaho National Laboratory is concerned that the sewage lagoons and land application site may be oversized for current and future flows. A further concern is the sustainability of the large volumes of supplemental water that are added to the system according to current operational practices. Therefore, this study was initiated to evaluate the system capacity, operational practices, and potential improvement alternatives, as warranted.

  4. Central Limit Theorems for Multicolor Urns with Dominated Colors

    CERN Document Server

    Berti, Patrizia; Pratelli, Luca; Rigo, Pietro

    2009-01-01

    An urn contains balls of d colors. At each time, a ball is drawn and then replaced together with a random number of balls of the same color. Assuming that some colors are dominated by others, we prove central limit theorems. Some statistical applications are discussed.

  5. 集中空调冷凝热回收技术在生活热水供应系统中的应用%Application of central air conditioning condense heat recovery technology to domestic hot water supply system

    Institute of Scientific and Technical Information of China (English)

    黄璞洁; 李艳霞; 何耀炳; 许伊那

    2011-01-01

    介绍\t了空调冷凝热回收技术的工作原理,计算确定了冷凝热回收机组和蓄热水箱的容量,并与传统的空调和生活热水供应系统进行比较.探讨了空调冷凝热回收技术在生活热水供应系统中的设计应用.%Based on the working principle, calculates the capacity of the condense heat recovery unit and heat storage water tank, and compares with the traditional air conditioning and domestic hot water supply system. Discusses the application of air conditioning condense heat recovery technology to the design of domestic hot water supply system.

  6. 探讨应用被动抬腿试验联合中心静脉压预测老年脓毒症患者的容量反应性%To Explore the Application of Passive Leg Raising Combined With Central Venous Pressure Predict Volume Responsiveness in Elderly Patients With Sepsis

    Institute of Scientific and Technical Information of China (English)

    农忻月

    2016-01-01

    目的:研究分析应用被动抬腿试验联合中心静脉压预测老年脓毒症患者的容量反应性。方法选取2015年10月~2016年3月我院收治的老年脓毒症患者40例,通过容量负荷试验后每搏量的增加值情况分为观察组与对照组。结果观察组患者扩容后心率低于对照组患者,差异具有统计学意义(P<0.05)。观察组患者扩容后动脉压、每搏量、心输出量以及氧合指数均高于对照组患者,差异具有统计学意义(P<0.05)。结论观察组患者扩容后心输出量增加,而中心静脉压降低,所以应用被动抬腿试验联合中心静脉压能有效预测老年脓毒症患者的容量反应性。%Objective To study the analysis application of passive leg joint central venous pressure prediction capacity reactivity in elderly patients with sepsis. Methods 40 patients with sepsis were select from October 2015 to March 2016 in our hospital, through the capacity load experiment after stroke volume of added value is divided into observation group and control group.Results Observation group of patients with enlarged heart rate was signiifcantly lower than the control group patients, difference is statistically signiifcant (P<0.05). Observation group of patients expansion after arterial pressure, stroke volume, cardiac output and oxygenation index were signiifcantly higher than that of control group patients, difference is statistically signiifcant (P<0.05).Conclusion To observe the way patients expansion increased markedly, and the middle of the back the output and central venous pressure has a significant decrease, so the application of combined central venous pressure passive leg lifts test can effectively predict the capacity of the elderly patients with sepsis reactivity.

  7. Equipment Parameters Application Solution Based on the Equipment Centralized Monitoring System and the Equipment Operation and Maintenance Platform%基于设备集中监控系统和设备运维平台的设备参数应用解决方案

    Institute of Scientific and Technical Information of China (English)

    罗科坚

    2014-01-01

    ATC equipment parameters have a great significance to equipment normal operation for the reason that ATC equipment pa-rameters reflect the equipment status. Recording relevant parameters of the daily equipment operation status is an important work of the e-quipment maintenance personnel. Currently, there are many problems such as the high maintenance costs of equipment parameters and low efficiency of manual records, even some missing, mistaken fill records or inevitably appearing non-standard records. In order to solve these problems, this paper presents an equipment parameters application solution based on the equipment centralized monitoring system and the equipment operation and maintenance platform, considering the Central South ATC equipment centralized monitoring system and equipment operation and maintenance platform for the analysis and processing of the equipment parameters, providing a more intuitive graphical showing way for the maintenance personnel, and providing a more intuitive and effective analytical tools. This equipment pa-rameters application solution can help to improve the reliability and accuracy of maintenance of equipment parameters, and reduce costs of equipment operation and maintenance.%空管设备参数反映设备的运行状况,对设备的正常运行具有重要意义。记录设备日常运行的相关参数是设备维护人员的重要工作内容,设备参数的维护成本高,人工记录效率低,漏填、误填或记录不规范的情况不可避免出现等,为了解决这些问题,本文提出一种基于设备集中监控系统和设备运行维护平台的设备参数应用解决方案,综合考虑中南空管设备集中监控系统和设备运行维护平台,对设备参数进行分析处理,以更直观的图形方式展现给使用人员,提供直观有效的分析手段,有利于提高设备参数维护的可靠性和准确性、降低设备运维成本。

  8. Network centrality of metro systems.

    Directory of Open Access Journals (Sweden)

    Sybil Derrible

    Full Text Available Whilst being hailed as the remedy to the world's ills, cities will need to adapt in the 21(st century. In particular, the role of public transport is likely to increase significantly, and new methods and technics to better plan transit systems are in dire need. This paper examines one fundamental aspect of transit: network centrality. By applying the notion of betweenness centrality to 28 worldwide metro systems, the main goal of this paper is to study the emergence of global trends in the evolution of centrality with network size and examine several individual systems in more detail. Betweenness was notably found to consistently become more evenly distributed with size (i.e. no "winner takes all" unlike other complex network properties. Two distinct regimes were also observed that are representative of their structure. Moreover, the share of betweenness was found to decrease in a power law with size (with exponent 1 for the average node, but the share of most central nodes decreases much slower than least central nodes (0.87 vs. 2.48. Finally the betweenness of individual stations in several systems were examined, which can be useful to locate stations where passengers can be redistributed to relieve pressure from overcrowded stations. Overall, this study offers significant insights that can help planners in their task to design the systems of tomorrow, and similar undertakings can easily be imagined to other urban infrastructure systems (e.g., electricity grid, water/wastewater system, etc. to develop more sustainable cities.

  9. Network centrality of metro systems.

    Science.gov (United States)

    Derrible, Sybil

    2012-01-01

    Whilst being hailed as the remedy to the world's ills, cities will need to adapt in the 21(st) century. In particular, the role of public transport is likely to increase significantly, and new methods and technics to better plan transit systems are in dire need. This paper examines one fundamental aspect of transit: network centrality. By applying the notion of betweenness centrality to 28 worldwide metro systems, the main goal of this paper is to study the emergence of global trends in the evolution of centrality with network size and examine several individual systems in more detail. Betweenness was notably found to consistently become more evenly distributed with size (i.e. no "winner takes all") unlike other complex network properties. Two distinct regimes were also observed that are representative of their structure. Moreover, the share of betweenness was found to decrease in a power law with size (with exponent 1 for the average node), but the share of most central nodes decreases much slower than least central nodes (0.87 vs. 2.48). Finally the betweenness of individual stations in several systems were examined, which can be useful to locate stations where passengers can be redistributed to relieve pressure from overcrowded stations. Overall, this study offers significant insights that can help planners in their task to design the systems of tomorrow, and similar undertakings can easily be imagined to other urban infrastructure systems (e.g., electricity grid, water/wastewater system, etc.) to develop more sustainable cities. PMID:22792373

  10. Coverage centralities for temporal networks

    CERN Document Server

    Takaguchi, Taro; Yoshida, Yuichi

    2015-01-01

    Structure of real networked systems, such as social relationship, can be modeled as temporal networks in which each edge appears only at the prescribed time. Understanding the structure of temporal networks requires quantifying the importance of a temporal vertex, which is a pair of vertex index and time. In this paper, we define two centrality measures of a temporal vertex by the proportion of (normal) vertex pairs, the quickest routes between which can (or should) use the temporal vertex. The definition is free from parameters and robust against the change in time scale on which we focus. In addition, we can efficiently compute these centrality values for all temporal vertices. Using the two centrality measures, we reveal that distributions of these centrality values of real-world temporal networks are heterogeneous. For various datasets, we also demonstrate that a majority of the highly central temporal vertices are located within a narrow time window around a particular time. In other words, there is a bo...

  11. Adaptação para a língua Portuguesa e aplicação de protocolo de avaliação das disartrias de origem central em pacientes com Doença de Parkinson Adjustment to the Portuguese and application to patients with Parkinson's disease of protocol within central origin dysarthrias' assessment

    Directory of Open Access Journals (Sweden)

    Angélica Suelen Fracassi

    2011-12-01

    Full Text Available OBJETIVO: traduzir e adaptar protocolo desenvolvido por pesquisadores alemães, adequando-o às características fonéticas e linguísticas do português falado no Brasil. Caracterizar os componentes de fala mais alterados na população com doença de Parkinson, comparando-os com grupo de sujeitos normais na mesma faixa etária. MÉTODOS: realizou-se a tradução e adaptação do protocolo. Posteriormente foram avaliados 21 pacientes com diagnóstico neurológico de Doença de Parkinson nos estágios Hoehn &Yarh, entre 2 e 3, e 10 sujeitos normais. O protocolo incluía avaliação da respiração, fonação, ressonância, articulação, prosódia e a análise acústica dos parâmetros vocais. RESULTADOS: o protocolo mostrou-se de fácil aplicação clínica. Nos sujeitos com doença de Parkinson foram observadas alterações predominantes na fonação (85,9% e articulação (42,9%. CONCLUSÃO: o estudo demonstrou ser o protocolo uma ferramenta eficiente para a avaliação da disartria em pacientes com doença de Parkinson.PURPOSE: to translate and adapt the protocol developed by German researchers, adjusting it to the phonetic and linguistic characteristics of Brazilian Portuguese. Observe the amended speech components in a group of patients with Parkinson's disease, and comparing them with normal subjects in the same age. METHOD: twenty one patients with neurological diagnosis of Parkinson's disease in the Hoehn & Yarh stages (2-3, and 10 control subjects were assessed. The protocol was translated, adjusted and applied to the subjects of both control and Parkinson's disease group, assessing the breathing, phonation, resonance, articulation, prosody and acoustic analysis. RESULTS: in the dysarthria evaluation, the protocol showed to be simple and it presented a fast clinical application. In the subjects with Parkinson's disease, we observed alterations in both phonation (85.9% and articulation (42.9%. CONCLUSION: the study demonstrated that the

  12. Pathophysiology of central sleep apneas.

    Science.gov (United States)

    Hernandez, Adam B; Patil, Susheel P

    2016-05-01

    The transition from wake to sleep is accompanied by a host of physiologic changes, which result in major alterations in respiratory control and may result in sleep-related breathing disorders. The central sleep apneas are a group of sleep-related breathing disorders that are characterized by recurrent episodes of airflow reduction or cessation due to a temporary reduction or absence of central respiratory drive. The fundamental hallmark of central sleep apnea (CSA) disorders is the presence of ventilatory control instability; however, additional mechanisms play a role in one or more specific manifestations of CSA. CSA may manifest during conditions of eucapnia/hypocapnia or chronic hypercapnia, which is a useful clinical classification that lends understanding to the underlying pathophysiology and potential therapies. In this review, an overview of normal breathing physiology is provided, followed by a discussion of pathophysiologic mechanisms that promote CSA and the mechanisms that are specific to different manifestations of CSA. PMID:26782104

  13. Central Clearing of OTC Derivatives

    DEFF Research Database (Denmark)

    Cont, Rama; Kokholm, Thomas

    2014-01-01

    We study the impact of central clearing of over-the-counter (OTC) transactions on counterparty exposures in a market with OTC transactions across several asset classes with heterogeneous characteristics. The impact of introducing a central counterparty (CCP) on expected interdealer exposure...... is determined by the tradeoff between multilateral netting across dealers on one hand and bilateral netting across asset classes on the other hand. We find this tradeoff to be sensitive to assumptions on heterogeneity of asset classes in terms of `riskyness' of the asset class as well as correlation...... of exposures across asset classes. In particular, while an analysis assuming independent, homogeneous exposures suggests that central clearing is efficient only if one has an unrealistically high number of participants, the opposite conclusion is reached if differences in riskyness and correlation across asset...

  14. Spatio-temporal Dynamics of Land-use and Land-cover Change: A Multi-agent Simulation Model and Its Application to an Upland Watershed in Central Vietnam

    Science.gov (United States)

    Le, Q.; Vlek, P. L.; Park, S.

    2005-12-01

    flexible interactions among human and landscape agents, and monitors consequent land-use changes and associated socio-economic dynamics. The model was applied in a watershed of about 100 km2 in A-Luoi district, Central Vietnam. Spatially explicit data were obtained from Landsat ETM images, thematic maps, an extensive forest inventory, and an intensive household survey. Field data were used for calibrating agent's parameters and develop an initial database for simulation runs. Scenarios of land-use changes under different policy options on forest protection zoning, agrochemical subsidies and agricultural extension were generated to evaluate the consequences of such policy interventions. Preliminary simulation runs for 10 different policy options suggest that reducing the current proportion of protected area from 90% to 50% and increasing the enforcement of protection, together with the provision of extension services for a third of the total population, and subsidizing 5% of the population with agrochemicals ($US 16 household-1 year-1) would, on average, increase per capita gross income by 15% and significantly reduce forest degradation compared to the scenario based on the status quo (i.e., the policy settings of 2002).

  15. 中原石油污染土壤原位微生物生态修复技术的应用%Application research of microbial and ecological remediation for oil contaminated soil in Central Plains

    Institute of Scientific and Technical Information of China (English)

    张胜; 陈立; 李政红; 张翠云; 殷密英; 马琳娜; 何泽; 孙振华; 张发旺

    2011-01-01

    The field remediation of the oil residue pollution in soil were carried out in Zhongyuan Oil Field, which using the optimistic techniques of in-situ microbial communities combining with the physical and chemistrial methods. The results showed that degradation rate can reach 99% as the oil content of 2 898.25 mg/kg in polluted soil after 99 d microbial and ecological remediation, which provide us the feasible technology and application of oil residue pollution remediation in soil at oilfields.%利用优化原位土著微生物菌群辅以物理和化学相结合的生态修复技术,进行了河南中原油田石油残留污染土壤的野外修复应用研究.修复结果显示,土壤中残留石油含量平均在2 898.25 mg/kg时,经过99 d微生物生态修复技术的实施,土壤中石油含量降解可达99%以上,为油田区土壤石油残留污染的修复提供了技术方法和推广应用的可行性研究.

  16. Analysis of the three dimensional core kinetics NESTLE code coupling with the advanced thermo-hydraulic code systems, RELAP5/SCDAPSIM and its application to the Laguna Verde Central reactor

    International Nuclear Information System (INIS)

    The objective of the written present is to propose a methodology for the joining of the codes RELAP5/SCDAPSIM and NESTLE. The development of this joining will be carried out inside a doctoral program of Engineering in Energy with nuclear profile of the Ability of Engineering of the UNAM together with the National Commission of Nuclear Security and Safeguards (CNSNS). The general purpose of this type of developments, is to have tools that are implemented by multiple programs or codes such a that systems or models of the three-dimensional kinetics of the core can be simulated and those of the dynamics of the reactor (water heater-hydraulics). In the past, by limitations for the calculation of the complete answer of both systems, the developed models they were carried out for separate, putting a lot of emphasis in one but neglecting the other one. These methodologies, calls of better estimate, will be good to the nuclear industry to evaluate, with more high grades of detail, the designs of the nuclear power plant (for modifications to those already existent or for new concepts in the designs of advanced reactors), besides analysing events (transitory and have an accident), among other applications. The coupled system was applied to design studies and investigation of the Laguna Verde Nuclear power plant (CNLV). (Author)

  17. Network Centrality of Metro Systems

    OpenAIRE

    Sybil Derrible

    2012-01-01

    Whilst being hailed as the remedy to the world's ills, cities will need to adapt in the 21(st) century. In particular, the role of public transport is likely to increase significantly, and new methods and technics to better plan transit systems are in dire need. This paper examines one fundamental aspect of transit: network centrality. By applying the notion of betweenness centrality to 28 worldwide metro systems, the main goal of this paper is to study the emergence of global trends in the e...

  18. MASSIVE PARALLELISM WITH GPUS FOR CENTRALITY RANKING IN COMPLEX NETWORKS

    Directory of Open Access Journals (Sweden)

    Frederico L. Cabral

    2014-10-01

    Full Text Available Many problems in Computer Science can be modelled using graphs. Evaluating node centrality in complex networks, which can be considered equivalent to undirected graphs, provides an useful metric of the relative importance of each node inside the evaluated network. The knowledge on which the most central nodes are, has various applications, such as improving information spreading in diffusion networks. In this case, most central nodes can be considered to have higher influence rates over other nodes in the network. The main purpose in this work is developing a GPU based and massively parallel application so as to evaluate the node centrality in complex networks using the Nvidia CUDA programming model. The main contribution of this work is the strategies for the development of an algorithm to evaluate the node centrality in complex networks using Nvidia CUDA parallel programming model. We show that the strategies improves algorithm´s speed-up in two orders of magnitude on one NVIDIA Tesla k20 GPU cluster node, when compared to the hybrid OpenMP/MPI algorithm version, running in the same cluster, with 4 nodes 2 Intel(R Xeon(R CPU E5-2660 each, for radius zero.

  19. Experiment and Demonstration of Application Effects of Slow -release Fertilizer on Summer Corn in Central Region of Shandong%高效缓释肥在鲁中夏玉米上的应用效果试验示范

    Institute of Scientific and Technical Information of China (English)

    郭跃升; 马荣辉; 高瑞杰; 邢晓飞; 王健; 严芳; 王桂香; 马文丽

    2015-01-01

    The effects of slow -release fertilizer on the agronomic characters,yield and nitrogen utiliza-tion under synchronized seeding and fertilization were studied by the field experiment.The results showed that the corn agronomic characteristics were effectively improved by application of slow -release fertilizer,single basal application could solve the problem of fertilizer shortage at the late growth stage of corn.The summer corn yields under the slow -release fertilizer treatment and 90% slow -release fertilizer treatment had no sig-nificant difference,but both were significantly higher than the yield under conventional fertilizer treatment. The yield under 90% slow -release fertilizer treatment was the highest,that of two experiment sites reached 688.3 kg and 711.0 kg per 666.7m2 .The nitrogen utilization of slow -release fertilizer treatment was signifi-cantly higher than the formula fertilizer and conventional fertilization.The nitrogen utilization under 90% slow-release fertilizer was the highest,which was higher than conventional fertilization by 11.25,15.68 percent point and 14.42,21.01 percent point respectively.The results indicated that the treatment of 90% slow -re-lease fertilizer had significant effect on decreasing cost and increasing benefit.%通过大田试验示范研究了缓释肥在玉米种肥同播条件下对玉米农艺性状、产量及氮肥利用率的影响。结果表明:施用缓释肥能有效改善玉米各农艺性状,一次性施用不会造成玉米生长后期脱肥;对比各处理玉米产量,全量缓控释肥和90%缓释肥两处理差异不显著,极显著高于习惯施肥处理,90%缓释肥处理玉米产量最高,两处试验点666.7m2产量分别为688.3 kg 和711.0 kg;全量缓释肥处理的氮肥利用率明显高于普通配方肥和习惯施肥,其中,以90%缓释肥处理氮肥利用率最高,比普通配方肥提高11.25个和15.68个百分点,分别比习惯施肥提高14.42

  20. Endodontic applications of a short pulsed FR Nd:YAG dental laser: photovaporization of extruded pulpal tissue following traumatic fractures of two maxillary central incisors--a clinical trial repor

    Science.gov (United States)

    Gregg, Robert H., II

    1992-06-01

    and identify risks for developing external and/or internal resorption after intracanal application of pulsed FR Nd:YAG laser energy.

  1. /S/ in Central American Spanish.

    Science.gov (United States)

    Lipski, John M.

    1985-01-01

    Describes the behavior of the phoneme /s/ in Central American Spanish by comparing the speech patterns of residents of Guatemala City, San Salvador, Tegucigalpa, San Jose, and Managua. Considers the possible diachronic processes which could have given rise to the current configurations and the theoretical consequences implied by the…

  2. Copycats of the Central Himalayas

    NARCIS (Netherlands)

    P.A. Arora (Payal)

    2009-01-01

    textabstractThis case study highlights practices of a rarely documented group of neo-users of the Internet or newbies from Central Himalayas, serving as a catalyst for delving deeply into the act of ‘plagiarism’ in online learning By looking at such ‘learning’ practices away from schools, namely at

  3. Illustrating the Central Limit Theorem

    Science.gov (United States)

    Corcoran, Mimi

    2016-01-01

    Statistics is enjoying some well-deserved limelight across mathematics curricula of late. Some statistical concepts, however, are not especially intuitive, and students struggle to comprehend and apply them. As an AP Statistics teacher, the author appreciates the central limit theorem as a foundational concept that plays a crucial role in…

  4. Payments and Central Bank Policy

    DEFF Research Database (Denmark)

    Korsgaard, Søren

    This thesis consists of three chapters. The rst, "Paying for Payments", examines the role of interchange fees in payment card networks. The second, "Bank Liquidity and the Interbank Market" (co-authored with Mikael Reimer Jensen), investigates how banks' liquidity holdings at the central bank a e...

  5. New Economy, Old Central Banks?

    NARCIS (Netherlands)

    Berk, Jan Marc

    2002-01-01

    Proponents of the so-called New Economy claim that it entails a structural change of the economy. Such a change, in turn, would require the central bank to rethink its monetary policy to the extent that traditional relationships between inf1ation and economic growth are no longer valid. But such a r

  6. The CMS central hadron calorimeter

    Energy Technology Data Exchange (ETDEWEB)

    Freeman, J.; E892 Collaboration

    1996-12-31

    The CMS central hadron calorimeter is a copper absorber/ scintillator sampling structure. We describe design choices that led us to this concept, details of the mechanical and optical structure, and test beam results. We discuss calibration techniques, and finally the anticipated construction schedule.

  7. Centrality Metric for Dynamic Networks

    CERN Document Server

    Lerman, Kristina; Kang, Jeon Hyung

    2010-01-01

    Centrality is an important notion in network analysis and is used to measure the degree to which network structure contributes to the importance of a node in a network. While many different centrality measures exist, most of them apply to static networks. Most networks, on the other hand, are dynamic in nature, evolving over time through the addition or deletion of nodes and edges. A popular approach to analyzing such networks represents them by a static network that aggregates all edges observed over some time period. This approach, however, under or overestimates centrality of some nodes. We address this problem by introducing a novel centrality metric for dynamic network analysis. This metric exploits an intuition that in order for one node in a dynamic network to influence another over some period of time, there must exist a path that connects the source and destination nodes through intermediaries at different times. We demonstrate on an example network that the proposed metric leads to a very different ...

  8. A First for Central America

    Institute of Scientific and Technical Information of China (English)

    2011-01-01

    FTA gives impetus to China’s trade with Costa Rica and other countries in the region The free trade agreement (FTA) between China and Costa Rica, signed in April 2010,came into effect on August 1.It was the first free trade pact between China and a Central

  9. The MEANING multilingual central repository

    NARCIS (Netherlands)

    Atserias, J.; Villarejo, L.; Rigau, G.; Agirre, E.; Carroll, J.; Magnini, B.; Vossen, P.

    2004-01-01

    This paper describes the first version of the Multilingual Central Repository, a lexical knowledge base developed in the framework of the MEANING project. Currently the MCR integrates into the EuroWordNet framework five local wordnets (including four versions of the English WordNet from Princeton),

  10. Central Libraries in Uncertain Times.

    Science.gov (United States)

    Kenney, Brian J.

    2001-01-01

    Discusses security and safety issues for public libraries, especially high-profile central facilities, in light of the September 11 terrorist attacks. Highlights include inspecting bags as patrons enter as well as exit; the need for security guidelines for any type of disaster or emergency; building design; and the importance of communication.…

  11. Central limit theorem for reducible and irreducible open quantum walks

    Science.gov (United States)

    Sadowski, Przemysław; Pawela, Łukasz

    2016-07-01

    In this work we aim at proving central limit theorems for open quantum walks on {mathbb {Z}}^d. We study the case when there are various classes of vertices in the network. In particular, we investigate two ways of distributing the vertex classes in the network. First, we assign the classes in a regular pattern. Secondly, we assign each vertex a random class with a transition invariant distribution. For each way of distributing vertex classes, we obtain an appropriate central limit theorem, illustrated by numerical examples. These theorems may have application in the study of complex systems in quantum biology and dissipative quantum computation.

  12. TEACHING ENGLISH IN SEVERAL CENTRAL AND EASTERN EUROPEAN COUNTRIES

    Directory of Open Access Journals (Sweden)

    Sim Monica Ariana

    2008-05-01

    Full Text Available The Central and Eastern European countries find themselves at present, following a period of transition in all domains, education included. One of the greatest challenges is providing sufficient foreign language education so as to meet the growing demand especially after along period of time when foreign languages were seriously and damagingly neglected. This paper is an attempt to briefly present the way English language is taught in several Central and Eastern European Countries as well as to underline the importance of this educational process and maybe to offer some applicable solutions to teaching English in Romania

  13. Greening File Distribution: Centralized or Distributed?

    CERN Document Server

    Verma, Kshitiz; Anta, Antonio Fernández; Rumín, Rubén Cuevas; Azcorra, Arturo

    2011-01-01

    Despite file-distribution applications are responsible for a major portion of the current Internet traffic, so far little effort has been dedicated to study file distribution from the point of view of energy efficiency. In this paper, we present a first approach at the problem of energy efficiency for file distribution. Specifically, we first demonstrate that the general problem of minimizing energy consumption in file distribution in heterogeneous settings is NP-hard. For homogeneous settings, we derive tight lower bounds on energy consumption, and we design a family of algorithms that achieve these bounds. Our results prove that collaborative p2p schemes achieve up to 50% energy savings with respect to the best available centralized file distribution scheme. Through simulation, we demonstrate that in more realistic cases (e.g., considering network congestion, and link variability across hosts) we validate this observation, since our collaborative algorithms always achieve significant energy savings with res...

  14. Central configurations, periodic orbits, and Hamiltonian systems

    CERN Document Server

    Llibre, Jaume; Simó, Carles

    2015-01-01

    The notes of this book originate from three series of lectures given at the Centre de Recerca Matemàtica (CRM) in Barcelona. The first one is dedicated to the study of periodic solutions of autonomous differential systems in Rn via the Averaging Theory and was delivered by Jaume Llibre. The second one, given by Richard Moeckel, focusses on methods for studying Central Configurations. The last one, by Carles Simó, describes the main mechanisms leading to a fairly global description of the dynamics in conservative systems. The book is directed towards graduate students and researchers interested in dynamical systems, in particular in the conservative case, and aims at facilitating the understanding of dynamics of specific models. The results presented and the tools introduced in this book include a large range of applications.

  15. Central Facilities Area Sewage Lagoon Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Giesbrecht, Alan [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-03-01

    The Central Facilities Area (CFA) located in Butte County, Idaho at Idaho National Laboratory (INL) has an existing wastewater system to collect and treat sanitary wastewater and non contact cooling water from the facility. The existing treatment facility consists of three cells: Cell 1 has a surface area of 1.7 acres, Cell 2 has a surface area of 10.3 acres, and Cell 3 has a surface area of 0.5 acres. If flows exceed the evaporative capacity of the cells, wastewater is discharged to a 73.5 acre land application site that utilizes a center pivot irrigation sprinkler system. The purpose of this current study is to update the analysis and conclusions of the December 2013 study. In this current study, the new seepage rate and influent flow rate data have been used to update the calculations, model, and analysis.

  16. Emerging infections of the central nervous system.

    Science.gov (United States)

    Lyons, Jennifer; McArthur, Justin

    2013-12-01

    Emerging infections affecting the central nervous system often present as encephalitis and can cause substantial morbidity and mortality. Diagnosis requires not only careful history taking, but also the application of newly developed diagnostic tests. These diseases frequently occur in outbreaks stemming from viruses that have mutated from an animal host and gained the ability to infect humans. With globalization, this can translate to the rapid emergence of infectious clusters or the establishment of endemicity in previously naïve locations. Since these infections are often vector borne and effective treatments are almost uniformly lacking, prevention is at least as important as prompt diagnosis and institution of supportive care. In this review, we focus on some of the recent literature addressing emerging and resurging viral encephalitides in the United States and around the world-specifically, West Nile virus, dengue, polio, and cycloviruses. We also discuss new, or "emerging," techniques for the precise and rapid diagnosis of encephalitides. PMID:24136412

  17. Towards Quantum Transport for Central Nuclear Reactions

    CERN Document Server

    Danielewicz, Pawel; Barker, Brent

    2016-01-01

    Nonequilibrium Green's functions represent a promising tool for describing central nuclear reactions. Even at the single-particle level, though, the Green's functions contain more information that computers may handle in the foreseeable future. In this study, we explore slab collisions in one dimension, first in the mean field approximation and demonstrate that only function elements close to the diagonal in arguments are relevant, in practice, for the reaction calculations. This bodes well for the application of the Green's functions to the reactions. Moreover we demonstrate that an initial state for a reaction calculation may be generated through adiabatic transformation of interactions. Finally, we report on our progress in incorporating correlations into the dynamic calculations.

  18. 7 CFR 319.56-25 - Papayas from Central America and Brazil.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Papayas from Central America and Brazil. 319.56-25... § 319.56-25 Papayas from Central America and Brazil. The Solo type of papaya may be imported into the... section and all other applicable provisions of this subpart. (a) The papayas were grown and packed...

  19. Application of mouse nervous growth factor on hand-foot-mouth disease combined with central nervous system damage%鼠神经生长因子治疗手足口病合并中枢神经系统损害的研究

    Institute of Scientific and Technical Information of China (English)

    宋蕊; 冯亮; 李兴旺; 徐艳丽; 卢联合; 蒋荣猛; 陈志海

    2011-01-01

    Objective To investigate the application of mouse nervous growth factor (mNGF) on patients with hand-foot-and-mouth disease (HFMD) combined with central nervous system damage. Methods Clinical data of 48 patients with HFMD combined with central nervous system damage, admitted to our hospital and received treatment of mNGF from May 2008 to September 2010, were analyzed retrospectively. Results Children under 5 years old, especially between 1-3 years old, were the high-risk group of having HFMD combined with central nervous system damage. The average time of appearing of acute flaccid paralysis (AFP) and recovering of muscle strength were (7.1±3.6) d and (17.5±6.0) d, respectively. A total of 31 patients (64.58%) appeared vomiting, with its average times of appearance and disappearance as (4.29±3.10) d and (5.74±2.90) d, respectively. A total of 33 patients (68.75%) tended to appear panic symptoms, which appeared on (2.67±1.76) d and disappeared on (7.80± 2.76) d averagely. Laboratory test showed number of white blood cells and CK values were elevated of certain degree, and cerebrospinal fluid pressure and protein expression level were increased to varying degrees. MRI showed that bulbus medulla was the most likely to be involved, followed by brain stem and other parts. Conclusion Application of mNGF on patients with HFMD combined with central system damage may help to improve the neurologic symptoms and prognosis.%目的 探讨鼠神经生长因子在手足口病合并中枢神经系统损害患者治疗中的应用.方法 收集北京地坛医院自2008年5月至2010年9月收治的手足口病合并中枢神经系统损害并使用鼠神经生长因子治疗的48例患者的临床资料,采用回顾性分析方法总结其特点.结果 5岁以下尤其是1~3岁儿童是手足口病合并中枢神经系统损害高危人群.患者急性弛缓性麻痹症状出现时间平均在病程第(7.1±3.6)天,肌力恢复平均在第(17.5±6.0)天;呕吐症状出现

  20. Analysis of the Application Value of Ultrasonography in the Diagnosis of Fetal Malformation of the Central Nervous System%超声检查在胎儿中枢神经系统畸形诊断中的应用价值探析

    Institute of Scientific and Technical Information of China (English)

    花秋菊; 关云萍; 项宇识

    2015-01-01

    目的:针对超声检查在胎儿中枢神经系统畸形诊断中的应用价值进行探讨分析。方法选择于2012年12月—2013年12月在该院进行产前超声诊断的70例单胎孕妇为研究对象,所有孕妇的胎儿经分娩后随访和引产后尸检证实为中枢神经系统畸形,分析超声表现和超声检查的临床符合率。结果所有胎儿中,引产68例,继续妊娠后生产2例。经病理检查证实该组胎儿严重小脑畸形1例,3例脊柱裂,11例脑膜脑膨出和脑膜膨出,23例为脑积水,31例为无脑畸形。通过产前超声检查诊断,胎儿中枢神经系统畸形包括:1例蛛网膜囊肿,3例脊柱裂,11例脑膜脑膨出和脑膜膨出,23例为脑积水,32例为无脑畸形。超声检查与病理检查结果的临床符合率98.9%,误诊率为1.1%。结论超声检查在胎儿中枢神经系统畸形诊断中的应用具有较高的诊断率,并且操作简便,无创伤,可以作为产前排除胎儿中枢神经系统畸形的重要方法。%Objective To explore and analyze the application value of ultrasonography in the diagnosis of fetal malformation of the central nervous system. Methods 70 singleton pregnant women underwent prenatal ultrasound diagnosis in our hospital from De-cember 2012 to December 2013 were selected as the subjects. All the fetuses were confirmed as malformation of the central ner-vous system by follow-up after delivery or autopsy after induced labour. And the clinical coincidence rate of ultrasonic manifesta-tions and ultrasonic examination was analyzed. Results Of all the fetuses, there were 68 cases of induced abortion, 2 cases of de-livery after continued pregnancy. It was confirmed by the pathological examination that there was 1 case with cerebellar malforma-tion, 3 cases with spina bifida, 11 cases with encephalomeningocele and meningiocele, 23 cases with hydrocephalus, 31 cases with anencephaly. The prenatal ultrasonography showed

  1. A dynamical systems view of network centrality.

    Science.gov (United States)

    Grindrod, Peter; Higham, Desmond J

    2014-05-01

    To gain insights about dynamic networks, the dominant paradigm is to study discrete snapshots, or timeslices, as the interactions evolve. Here, we develop and test a new mathematical framework where network evolution is handled over continuous time, giving an elegant dynamical systems representation for the important concept of node centrality. The resulting system allows us to track the relative influence of each individual. This new setting is natural in many digital applications, offering both conceptual and computational advantages. The novel differential equations approach is convenient for modelling and analysis of network evolution and gives rise to an interesting application of the matrix logarithm function. From a computational perspective, it avoids the awkward up-front compromises between accuracy, efficiency and redundancy required in the prevalent discrete-time setting. Instead, we can rely on state-of-the-art ODE software, where discretization takes place adaptively in response to the prevailing system dynamics. The new centrality system generalizes the widely used Katz measure, and allows us to identify and track, at any resolution, the most influential nodes in terms of broadcasting and receiving information through time-dependent links. In addition to the classical static network notion of attenuation across edges, the new ODE also allows for attenuation over time, as information becomes stale. This allows 'running measures' to be computed, so that networks can be monitored in real time over arbitrarily long intervals. With regard to computational efficiency, we explain why it is cheaper to track good receivers of information than good broadcasters. An important consequence is that the overall broadcast activity in the network can also be monitored efficiently. We use two synthetic examples to validate the relevance of the new measures. We then illustrate the ideas on a large-scale voice call network, where key features are discovered that are not

  2. 全自动片剂摆药机在我院中心药房的应用%Application of Full-Automatic Tablet Dispensing Machine in the Central Pharmacy of Our Hospital

    Institute of Scientific and Technical Information of China (English)

    訾梅; 古艳婷

    2015-01-01

    OBJECTIVE:To provide references for rational application of full-automatic tablet dispensing machine in the inpa-tient pharmacy of the hospital. METHODS:According to the work flow and use of the machine,the errors and problems arising from the use thereof by our hospital were summarized and analyzed,and corresponding improvement measures and solutions were put forward. RESULTS & CONCLUSIONS:Common errors in the use of full-automatic tablet dispensing machine included errors for the machine(including in-box drug shortage warnings accounting for 58.61% and abnormal responses to the quantity of in-box drugs accounting for 36.96%),errors caused by human factors(including errors of inputting doctor’s order and errors of pharma-cist’s adding drugs)and errors of material installation and operation. The solutions put forward are as follows as adjusting the tilt angle of the outlet mouth and controlling the quantity of the drugs added to the box to reduce the errors for the machine;two phar-macists’checking doctor’s order in the hospital information system in advance to reduce the errors caused by human factors;carry-ing out operation training for operators to reduce the errors of material installation;designating special personnel to maintain the ma-chine,etc.%目的:为医院住院药房合理应用全自动片剂摆药机提供参考。方法:根据全自动片剂摆药机的工作流程和使用情况,总结分析我院在其使用中发生的差错及问题,并提出改进措施和解决方法。结果与结论:使用全自动片剂摆药机的常见差错包括自动摆药机发生的差错(其中药盒缺药报警占58.61%,药盒内数量反应错误占36.96%)、人为因素产生的差错(包括医嘱录入错误和药师加药错误)以及耗材安装操作差错。提出的解决方法包括调整出药口的倾斜角度、控制贮药盒内药品添加的数量以减少自动摆药机发生的差错;药师提前审核医院信

  3. From Centrality to Temporary Fame: Dynamic Centrality in Complex Networks

    OpenAIRE

    Braha, Dan; Bar-Yam, Yaneer

    2006-01-01

    We develop a new approach to the study of the dynamics of link utilization in complex networks using records of communication in a large social network. Counter to the perspective that nodes have particular roles, we find roles change dramatically from day to day. "Local hubs" have a power law degree distribution over time, with no characteristic degree value. Our results imply a significant reinterpretation of the concept of node centrality in complex networks, and among other conclusions su...

  4. Connecting Classroom and Cafeteria in a School Wellness Initiative

    Science.gov (United States)

    Grenci, Alexandra; Hughes, Luanne J.; Savoca, LeeAnne

    2011-01-01

    Purpose/Objectives: The Child Nutrition and WIC Reauthorization Act of 2004 required all school districts participating in federally funded child nutrition programs to adopt and implement a school wellness policy by the beginning of the 2006-2007 school year. One drawback of this federal mandate was that it did not provide funding to assist with…

  5. SMOKING / NON-SMOKING IN THE CERN RESTAURANTS AND CAFETERIAS

    CERN Multimedia

    Restaurant Supervisory Committee, tel. 77551

    2001-01-01

    As you may remember, all CERN buildings and cars are considered to be non-smoking areas with a few exceptions (Safety Instruction no. 46). The ban on smoking applies in particular to all public areas, such as restaurants and cafétérias. Smoking is therefore prohibited in all parts of the free-flow and the dining rooms. As for the cafétérias, they are divided into well-defined non-smoking and smoking areas, the latter being clearly indicated as such, i.e : Cafétéria of Restaurant no. 1 : at the back of the cafétéria (on the outside terrace side) opposite the Users' Office and the offices of the Staff Association; Cafétéria of Restaurant no. 2 : the full length of the cafétéria on the wineyard side, except for the room next to the entrance to the building, furnished with red arm-chairs; Cafétéria of Restaurant no. 3 : between the bar and the row of artificial ...

  6. Cafeteria Staff Perceptions of the New USDA School Meal Standards

    Science.gov (United States)

    Alcaraz, Brenda; Cullen, Karen Weber

    2014-01-01

    Purpose/Objectives: The new nutrition standards for the school meal programs implemented in 2012 align the school meal patterns with the US Dietary Guidelines for Americans, including more fruit, vegetable and whole grain offerings and minimum and maximum amount of calories per meal averaged over a week. The purpose of this study was to assess…

  7. Cafeteria staff perceptions of the new USDA school meal standards

    Science.gov (United States)

    The new nutrition standards for the school meal programs implemented in 2012 align the school meal patterns with the US Dietary Guidelines for Americans, including more fruit, vegetable and whole grain offerings and minimum and maximum amount of calories per meal averaged over a week. The purpose of...

  8. Development and Evaluation of the School Cafeteria Nutrition Assessment Measures

    Science.gov (United States)

    Krukowski, Rebecca A.; Philyaw Perez, Amanda G.; Bursac, Zoran; Goodell, Melanie; Raczynski, James M.; Smith West, Delia; Phillips, Martha M.

    2011-01-01

    Background: Foods provided in schools represent a substantial portion of US children's dietary intake; however, the school food environment has proven difficult to describe due to the lack of comprehensive, standardized, and validated measures. Methods: As part of the Arkansas Act 1220 evaluation project, we developed the School Cafeteria…

  9. RESTAURANT AND CAFETERIA SERVICES ARRANGEMENTS FOR 1 MAY 2002

    CERN Multimedia

    Restaurant Supervisory Committee

    2002-01-01

    1. Restaurants As Wednesday 1 May is an official CERN holiday, restaurants no. 2 (DSR: bldg. 504 - Meyrin) and no. 3 (Avenance: bldg. 866 - Prévessin) will be closed as from Tuesda 30 April at 18h00. They will reopen on Thursday 2 May at 6h30 (rest. no. 2) and at 7h00 (rest. no. 3). On 1 May, a limited service will be provided by restaurant no. 1 (COOP: bldg. 501 - Meyrin) from 8h00 to 21h00 with hot meals served from 11h30 to 14h00 and from 18h00 to 19h30. 2. Decentralised services No decentralised services (satellite cafétérias etc.) will operate. 3. Newspaper stand The newspaper kiosque in building 501 will be closed. Restaurant Supervisory Committee, tel. 77551

  10. RESTAURANT and CAFETERIA SERVICES: ARRANGEMENTS for MAY 1st, 2003

    CERN Multimedia

    2003-01-01

    1. Restaurants As Thursday, May 1st, is an official CERN holiday, restaurants no. 2 (DSR : Bldg. 504 - Meyrin) and no. 3 (Avenance : Bldg. 866 - Prévessin) will be closed as from Wednesday, April 30 at 18h00. They will reopen on Friday, May 2nd at 6h30 (rest. no. 2) and at 7h00 (rest. no. 3). On May 1st, a limited service will be provided by restaurant no. 1 (COOP : Bldg. 501 - Meyrin) from 8h00 to 21h00 with hot meals served from 11h30 to 14h00 and from 18h00 to 19h30. 2. Newspaper stand The newspaper kiosque run by restaurant no. 1 in building 501 will be closed. 3. Decentralised services No decentralised services (satellite cafétérias etc.) will operate on May 1st, but will resume their normal activites on Friday, May 2nd, except for those dependent on restaurant no. 3 (Prévessin site) which will not reopen until Monday, May 5, 2003.

  11. RESTAURANT AND CAFETERIA SERVICES ARRANGEMENTS FOR MAY 1ST, 2001

    CERN Multimedia

    Restaurant Supervisory Committee

    2001-01-01

    1. Restaurants As Tuesday, May 1st, is an official CERN holiday, restaurants no 2 (DSR : Bldg. 504 - Meyrin) and no 3 (Avenance : Bldg. 866 - Prévessin) will be closed as from Monday, April 30 at 18h00. They will reopen on Wednesday, May 2nd at 6h30 (rest. no 2) and at 7h00 (rest. no 3). On May 1st, a limited service will be provided by restaurant no. 1 (COOP : Bldg. 501 - Meyrin) from 8h00 to 21h00 with hot meals served from 11h30 to 14h00 and from 18h00 to 19h30. 2. Satellite cafétérias All satellite cafétérias will be closed on May 1st. They will all operate normally on Monday, April 30, except for buildings 17 (Meyrin), 865 and 892 (Prévessin) which will be closed. 3. Newspaper stand The newspaper kiosque in building 501 will be closed on May 1st.

  12. Central hypersensitivity in chronic musculoskeletal pain

    DEFF Research Database (Denmark)

    Curatolo, Michele; Arendt-Nielsen, Lars

    2015-01-01

    Clinical research has consistently detected alteration in central pain processing leading to hypersensitivity. Most methods used in humans are reliable and have face validity to detect widespread central hypersensitivity. However, construct validity is difficult to investigate due to lack of gold...... standards. Reference values in the pain-free population have been generated, but need replication. Research on pain biomarkers that reflect specific central hypersensitivity processes is warranted. Few studies have analyzed the prognostic value of central hypersensitivity. Most medications acting at central...

  13. Application of Neuronavigation and Electrophysiological Monitoring in the Resection of Lesions near the Central Sulcus%神经导航和电生理监测在中央沟附近病变切除术中的应用

    Institute of Scientific and Technical Information of China (English)

    陈汉民; 王文鑫; 廖圣芳

    2014-01-01

    Objective]To explore the application of neuronavigation and electrophysiological monitoring in the resection of lesions near the central sulcus .[Methods]A total of 14 patients with lesions near the central sulcus in our hospital underwent microsurgical procedures assisted with neuronavigation and electrophysiological monito‐ring .Clinical efficacy was observed .[Results]In the group ,9 patients underwent total resection and 5 patients un‐derwent partial resection .After operation ,contralateral limb muscle strength impairment occurred in 2 patients af‐ter operation ,and hemiplegia occurred in 1 patient ,and limb muscle strength impairment was aggravated in 2 pa‐tients .The 3 patients with limb movement disorder got better about one month after operation .[Conclusion]The combination of intraoperative neuronavigation and electrophysiological monitoring is of great clinical practical value in the resection of lesions near the central sulcus .%目的 探讨神经导航和电生理监测在中央沟附近病变切除术中的应用。方法 本院收治的14例中央沟附近病变患者,在神经导航和电生理监测下行显微手术切除病变,观察其临床疗效。结果 本组中病变全切除9例,大部分切除5例。术后出现对侧肢体肌力减退2例,偏瘫1例,术前肢体肌力减退加重2例,3例肢体运动障碍者术后1个月左右好转。结论 联合应用神经导航和电生理监测技术在中央沟附近病变切除术中具有较大的临床实用价值。

  14. 新疆某电厂办公区半集中式蒸发冷却空调系统的工程应用分析%In A Power Plant in Xinjiang Office Semi-central Evaporative Air-conditioning System Application Analysis

    Institute of Scientific and Technical Information of China (English)

    王伟; 黄翔; 孙铁柱; 吴生; 于优城; 唐永戬; 杨晓弟

    2012-01-01

    介绍了半集中式蒸发冷却空调系统的设计过程,对应用在新疆某电厂办公区的半集中式蒸发冷却空调系统进行详细的测试分析.测试结果表明:三级蒸发冷却新风机组将室外干球温度为35℃,湿球温度为19.8℃的空气,处理至干球温度为15℃低温空气送入室内.蒸发冷却高温冷水机组制取干球温度为17℃的冷水,完全满足干式风机盘管的要求.整个半集中式蒸发冷却串联系统中,风机盘管回水在高温表冷器中可以将室外空气的温度降低7℃以上,形成了冷量的多重利用.同时希望通过这样的实例设计过程分析为相关的设计人员提供一定的参考.%The design process of semi-central evaporative air conditioning system was briefly introduced, the application of a certain power plant in xinjiang office semi-central evaporative air conditioning system for detailed analysis of the test. Test results show that; three new air handling units to evaporative cooling outdoor dry bulb temperature of 35℃ , wet bulb temperature of 19. 8℃, air treatment to dry bulb temperature is 15℃ low temperature air into the room. Evaporative cooling high-temperature water chiller system to take dry-bulb temperature of 17℃ cold water, fully meet the requirements of dry-type fan coil. Evaporative cooling throughout the series semi-centralized system, fan coil return water at high temperatures can be cooler outdoor air temperature 7℃ lower than the formation of a cooling capacity of multiple use. Also hope that through this analysis of the relevant instance of the design process designers to provide a reference.

  15. Ground-water reconnaissance of the central Weber River area, Morgan and Summit Counties, Utah

    Science.gov (United States)

    Gates, Joseph S.; Steiger, Judy I.; Green, Ronald T.

    1984-01-01

    A reconnaissance of ground water in the central Weber River area obtained data to help State administrators devise a policy for acting on applications to appropriate ground water resulting from recent and future influxes of residents.

  16. Containment of a diffuse ionized mass orbiting around a magnetized central body

    International Nuclear Information System (INIS)

    The containment of a diffused and ionized mass orbiting around a magnetized central body is studied and the condition equation is established. Some qualitative and quantitative applications to the planetary cosmogony problems are developed. (Auth.)

  17. Centralized versus Decentralized Infrastructure Networks

    CERN Document Server

    Hines, Paul D H; Schläpfer, Markus

    2015-01-01

    While many large infrastructure networks, such as power, water, and natural gas systems, have similar physical properties governing flows, these systems tend to have distinctly different sizes and topological structures. This paper seeks to understand how these different size-scales and topological features can emerge from relatively simple design principles. Specifically, we seek to describe the conditions under which it is optimal to build decentralized network infrastructures, such as a microgrid, rather than centralized ones, such as a large high-voltage power system. While our method is simple it is useful in explaining why sometimes, but not always, it is economical to build large, interconnected networks and in other cases it is preferable to use smaller, distributed systems. The results indicate that there is not a single set of infrastructure cost conditions under which optimally-designed networks will have highly centralized architectures. Instead, as costs increase we find that average network size...

  18. Centrality in Interconnected Multilayer Networks

    CERN Document Server

    De Domenico, Manlio; Omodei, Elisa; Gómez, Sergio; Arenas, Alex

    2013-01-01

    Real-world complex systems exhibit multiple levels of relationships. In many cases, they require to be modeled by interconnected multilayer networks, characterizing interactions on several levels simultaneously. It is of crucial importance in many fields, from economics to biology, from urban planning to social sciences, to identify the most (or the less) influent nodes in a network. However, defining the centrality of actors in an interconnected structure is not trivial. In this paper, we capitalize on the tensorial formalism, recently proposed to characterize and investigate this kind of complex topologies, to show how several centrality measures -- well-known in the case of standard ("monoplex") networks -- can be extended naturally to the realm of interconnected multiplexes. We consider diagnostics widely used in different fields, e.g., computer science, biology, communication and social sciences, to cite only some of them. We show, both theoretically and numerically, that using the weighted monoplex obta...

  19. A centralized audio presentation manager

    Energy Technology Data Exchange (ETDEWEB)

    Papp, A.L. III; Blattner, M.M.

    1994-05-16

    The centralized audio presentation manager addresses the problems which occur when multiple programs running simultaneously attempt to use the audio output of a computer system. Time dependence of sound means that certain auditory messages must be scheduled simultaneously, which can lead to perceptual problems due to psychoacoustic phenomena. Furthermore, the combination of speech and nonspeech audio is examined; each presents its own problems of perceptibility in an acoustic environment composed of multiple auditory streams. The centralized audio presentation manager receives abstract parameterized message requests from the currently running programs, and attempts to create and present a sonic representation in the most perceptible manner through the use of a theoretically and empirically designed rule set.

  20. PRIMARY CENTRAL NERVOUS SYSTEM LYMPHOMA

    Directory of Open Access Journals (Sweden)

    S.S. Anvari

    2009-08-01

    Full Text Available ObjectivePrimary central nervous system lymphoma (PCNSL is an extremely rare condition in childhood. We report the first case of PCNSL in a child in Iran.Clinical presentationA nine-year-old boy was referred to Mofid Hospital with the history of headache of four months and seizure of 2 months duration. Magnetic resonance imaging of the brain revealed a hyper-intense lesion in left fronto-parietal area with secondary satellite lesions. Biopsy of the brain mass was performed. Pathologic findings showed brain lymphoma and immunohistochemistry confirmed this diagnosis. The treatment started with intrathecal and systemic chemotherapy in combination with radiotherapy.Keywords:Lymphoma, Primary central nervous system lymphoma (PCNSL, Children

  1. Celtic Sites of Central Iberia

    Science.gov (United States)

    Pérez Gutiérrez, Manuel

    This chapter concerns the astronomy practiced by Celtic peoples in some parts of central Iberia, specifically the Vetton and Celtiberian peoples, inhabitants of the so-called Late Iron Age. The construction of some elements of religion or worship was perfectly determined by geometry, topography, and especially astronomy, because their spatial orientation occurs in locations of great interest for maintaining the local calendar. The maintenance of this calendar was probably the primary objective of some of the elements studied.

  2. Information from the central stores

    CERN Multimedia

    GS Department

    2010-01-01

    All items sold in the CERN shop (Bldg. 33) are now available in the central stores (Bldg. 73) and can be purchased on-line via EDH “Material Request” or at the “Emergency Desk” of the stores on the ground floor of Bldg. 73. These items are visible in the CERN catalogue under the “SCEM” codes beginning with 92. Department of General Infrastructure Services (GS) GS-SEM Group

  3. Wine markets in central Europe

    OpenAIRE

    Š BOJNEC

    2013-01-01

    This paper analyses the tendencies of grapes growing, wine trading and wine price competitiveness in Central European region. Croatia is net exporter of wines, Hungary is net exporter of grapes and wines, and Austria, Slovakia, and Slovenia are net importers of grapes and wines. Reductions in vineyards and increase in yields are found for Austria, Hungary, and Slovakia. More stable developments in vineyards, but decline in yields, are found for Croatia and Slovenia. Grape production increases...

  4. Central collisions of heavy ions

    International Nuclear Information System (INIS)

    This report describes the activities of the Heavy Ion Physics Group at the University of California, Riverside from October 1, 1991 to September 30, 1992. During this period, the program focused on particle production at AGS energies, and correlation studies at the Bevalac in nucleus-nucleus central collisions. As part of the PHENIX collaboration, contributions were made to the Preliminary Conceptual Design Report (pCDR), and work on a RHIC silicon microstrip detector R ampersand D project was performed

  5. Plague in Central Java, Indonesia

    OpenAIRE

    Williams, J.E.; Hudson, B. W.; Turner, R W; Saroso, J. Sulianti; Cavanaugh, D. C.

    1980-01-01

    Plague in man occurred from 1968 to 1970 in mountain villages of the Boyolali Regency in Central Java. Infected fleas, infected rats, and seropositive rats were collected in villages with human plague cases. Subsequent isolations of Yersinia pestis and seropositive rodents, detected during investigations of rodent plague undertaken by the Government of Indonesia and the WHO, attested to the persistence of plague in the region from 1972 to 1974.

  6. Central Asian drug trafficking dilemma

    OpenAIRE

    McGowen, Richard S.

    2003-01-01

    Tajikistan, a state that is completely landlocked, consists of very rough terrain that is comprised of mountains, cliffs and glaciers. There are very few transportation links through the area that gives Tajikistan limited access to neighboring countries. Security problems resulting from the increasing flow of narcotics illegally smuggled across the 1200 km Tajikistan- Afghanistan border have become critical in understanding the nature of political instability within Central Asia. This thesis ...

  7. Optimal Central Counterparty Risk Management

    OpenAIRE

    Philipp Haene; Andy Sturm

    2009-01-01

    In order to protect themselves against the potential losses in case of a participant's default and to contain systemic risk, central counterparties (CCPs) need to maintain sufficient financial resources. Typically, these financial resources consist of margin requirements and contributions to a collective default fund. Based on a stylized model of CCP risk management, this article analyzes the main factors affecting the trade-off between margins and default fund. The optimal balance between th...

  8. Political centralization and government accountability

    OpenAIRE

    Boffa, Federico; Piolatto, Amedeo; Giacomo A. M. Ponzetto

    2011-01-01

    This paper explains why decentralization can undermine accountability and answers three questions: what determines if power should be centralized or decentralized when regions are heterogeneous? How many levels of government should there be? How should state borders be drawn? We develop a model of political agency in which voters differ in their ability to monitor rent-seeking politicians. We find that rent extraction is a decreasing and convex function of the share of informed...

  9. Kalmanovitz y la Banca central / Kalmanovitz and central banking

    OpenAIRE

    Maya Muñoz, Guillermo

    2004-01-01

    Salomón Kalmanovitz, Codirector del Banco de la República (B de la R) hasta enero de 2005, uno de los economistas colombianos más brillantes, publicó un libro titulado Ensayos sobre Banca Central, Comportamiento, Independencia e Historia (Norma, 2003). Si los estudiantes de economía de los años 70 y 80 estudiaron a un Kalmanovitz marxista, los estudiantes de hoy estudian a un economista ortodoxo y liberal, igualmente brillante. Kalmanovitz es un partidario de la independencia de la BC para la...

  10. From Centrality to Temporary Fame: Dynamic Centrality in Complex Networks

    CERN Document Server

    Braha, D; Braha, Dan; Bar-Yam, Yaneer

    2006-01-01

    We develop a new approach to the study of the dynamics of link utilization in complex networks using records of communication in a large social network. Counter to the perspective that nodes have particular roles, we find roles change dramatically from day to day. "Local hubs" have a power law degree distribution over time, with no characteristic degree value. Our results imply a significant reinterpretation of the concept of node centrality in complex networks, and among other conclusions suggest that interventions targeting hubs will have significantly less effect than previously thought.

  11. A centralized dose calculation system for radiation therapy.

    Science.gov (United States)

    Xiao, Y; Galvin, J

    2000-05-01

    Centralization of treatment planning in a radiation therapy department is a realistic strategy to achieve an integrated and quality-controlled planning system, especially for institutions with numerous affiliations. The rapid evolution of computer hardware and software technology makes this a distinct possibility. However, the procedure of three-dimensional treatment planning involves a number of steps, such as: (1) input of patient computed tomography (CT) images and contour information; (2) interactions with local devices such as a film digitizer; and (3) output of beam information to be integrated with the record and verify the system. A full-fledged realization of the web-based centralized three-dimensional treatment planning system will require an extensive commercial development effort. We have developed and incorporated a web-based Timer/Monitor Unit (MU) program as a first step towards the full implementation of a centralized treatment planning system. The software application was developed in JAVA language. It uses the internet server and client technology. With one server that can handle multiple threads, it is a simple process to access the application anywhere on the network with an internet browser. Both the essential data needed for the calculation and the results are stored on the server, which centralizes the maintenance of the software and the storage of patient information.

  12. TOKAMAK EQUILIBRIA WITH CENTRAL CURRENT HOLES AND NEGATIVE CURRENT DRIVE

    Energy Technology Data Exchange (ETDEWEB)

    CHU, M.S.; PARKS, P.B.

    2002-06-01

    OAK B202 TOKAMAK EQUILIBRIA WITH CENTRAL CURRENT HOLES AND NEGATIVE CURRENT DRIVE. Several tokamak experiments have reported the development of a central region with vanishing currents (the current hole). Straightforward application of results from the work of Greene, Johnson and Weimer [Phys. Fluids, 3, 67 (1971)] on tokamak equilibrium to these plasmas leads to apparent singularities in several physical quantities including the Shafranov shift and casts doubts on the existence of this type of equilibria. In this paper, the above quoted equilibrium theory is re-examined and extended to include equilibria with a current hole. It is shown that singularities can be circumvented and that equilibria with a central current hole do satisfy the magnetohydrodynamic equilibrium condition with regular behavior for all the physical quantities and do not lead to infinitely large Shafranov shifts. Isolated equilibria with negative current in the central region could exist. But equilibria with negative currents in general do not have neighboring equilibria and thus cannot have experimental realization, i.e. no negative currents can be driven in the central region.

  13. Determining Central Black Hole Masses in Distant Active Galaxies

    CERN Document Server

    Vestergaard, M

    2002-01-01

    An empirical relationship, of particular interest for studies of high redshift active galactic nuclei (AGNs) and quasars, between the masses of their central black-holes and rest-frame ultraviolet (UV) parameters measured in single-epoch AGN spectra is presented. This relationship is calibrated to recently measured reverberation masses of low-redshift AGNs and quasars. An empirical relationship between single-epoch rest-frame optical spectrophotometric measurements and the central masses is also presented. The UV relationship allows reasonable estimates of the central masses to be made of high-redshift AGNs and quasars for which these masses cannot be directly or easily measured by the techniques applicable to the lower luminosity, nearby AGNs. The central mass obtained by this method can be estimated to within a factor of ~3 for most objects. This is reasonable given the intrinsic uncertainty of a factor less than 2 in the primary methods used to measure the central masses of nearby inactive and active galax...

  14. Seismic risk assessment and application in the central United States

    Science.gov (United States)

    Wang, Z.

    2011-01-01

    Seismic risk is a somewhat subjective, but important, concept in earthquake engineering and other related decision-making. Another important concept that is closely related to seismic risk is seismic hazard. Although seismic hazard and seismic risk have often been used interchangeably, they are fundamentally different: seismic hazard describes the natural phenomenon or physical property of an earthquake, whereas seismic risk describes the probability of loss or damage that could be caused by a seismic hazard. The distinction between seismic hazard and seismic risk is of practical significance because measures for seismic hazard mitigation may differ from those for seismic risk reduction. Seismic risk assessment is a complicated process and starts with seismic hazard assessment. Although probabilistic seismic hazard analysis (PSHA) is the most widely used method for seismic hazard assessment, recent studies have found that PSHA is not scientifically valid. Use of PSHA will lead to (1) artifact estimates of seismic risk, (2) misleading use of the annual probability of exccedance (i.e., the probability of exceedance in one year) as a frequency (per year), and (3) numerical creation of extremely high ground motion. An alternative approach, which is similar to those used for flood and wind hazard assessments, has been proposed. ?? 2011 ASCE.

  15. Centralized Routing for Prolonged Network Lifetime in Wireless Sensor Networks

    OpenAIRE

    Hansen, Ewa

    2008-01-01

    In this thesis centralized routing methods for wireless sensor networks have been studied. The aim has been to prolong network lifetime by reducing the energy consumed by sensor-node communication. Wireless sensor networks are rapidly becoming common in application areas where information from many sensors is to be collected and acted upon. The use of wireless sensor networks adds flexibility to the network, and the cost of cabling can be avoided. Wireless sensor networks may consist of sever...

  16. Professional Nursing Duties in the Central Services: Hospital Pharmacy Nurses

    OpenAIRE

    Inmaculada Gómez-Villegas; Belén Ruíz-Pérez; Dolores López-del-Pino; Francisco García-España

    2015-01-01

    Introduction. The new demands of a fast changing world necessitate expanding the traditional concepts of nursing, extending the classical aspects to cover new areas. Purpose. Based on their professional duties, the nursing team in the pharmacy of a second-level hospital aimed to establish a theoretical and situational framework for nurses working in the central services. Material and Methods. Application of the nursing process to nursing work in an area with no direct contact with patients. R...

  17. Geoenvironmental problems and cross-border cooperation in Central America

    Institute of Scientific and Technical Information of China (English)

    Marek Graniczny; Jonas Satkunas; Jurga Lazauskiene; Jiri Sebesta

    2006-01-01

    @@ The International Workshop on "Geoenvironmental problems and cross-border cooperation in Central America" was organized in Managua, Nicaragua, 5-8 December, 2005 by the Working Group International Borders-Geoenvironmental Concerns (IBC), under the IUGS Commission on Geosciences for Environmental Management (GEM) and in the framework of the IUGS funded project "Application of geosciences for sustainable development of cross-border areas(GEOCrossBorder)".

  18. CHINA AND ENERGY SECURITY IN CENTRAL ASIA

    OpenAIRE

    Guang, Pan

    2007-01-01

    This paper is divided into three parts: China’s energy policy and energy development strategy; Central Asia’s significance for China’s overseas energy development strategy; and Central Asia’s energy security and energy development.

  19. Central diffractive resonance production at the LHC

    Directory of Open Access Journals (Sweden)

    Fiore Roberto

    2016-01-01

    Full Text Available Central production of resonances resulting from the scattering of Pomerons in the central rapidity region of proton-proton scattering is studied. Estimates for relevant cross sections are presented.

  20. Biomass energy in Central America

    International Nuclear Information System (INIS)

    The objective of this paper is to introduce the concept of biomass to energy issues and opportunities in Central America. In this region, made up of seven countries (Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua and Panama), the biomass sector has the potential to play a crucial role in alleviating the environmental and development predicaments faced by all economies of the region. This paper assesses the available biomass resources at the regional and country levels and gives an overview of the current utilization of biomass fuels. It also describes the overall context in which the biomass-to-energy initiatives are immersed. At the regional level, biomass energy consumption accounts for more than 50% of total energy consumption. In regard to the utilization of biomass for energy purposes, it is clear that Central America faces a critical juncture at two levels, both mainly in rural areas: in the productive sector and at the household level. The absence of sustainable development policies and practices has jeopardized the availability of biomass fuels, particularly wood. Firewood is an important source of energy for rural industries such as coffee processing, which is one of the largest productive activities in the region. This paper comments on some of the most successful technological innovations already in place in the region, for instance, the rapid development of co-generation projects by the sugar cane industry, especially in El Salvador and Guatemala, the substitution of coffee husks for firewood in coffee processing plants in Costa Rica and El Salvador and the sustainable use of pine forests for co-generation in Honduras. Only one out of every two inhabitants in Central America now has access to electricity from the public grid. Biomass fuels, mainly firewood but also, to a lesser extent, other crop residues such as corn stalks, are the main source of energy for cooking and heating by most of the population. (It is foreseen that by the end

  1. The ZEUS central tracking detector

    International Nuclear Information System (INIS)

    The Central Tracking Detector (CTD) of ZEUS covers a wide angular range, whilst the Forward Detector - comprising the Forward Tracking Detector (FTD) and electron identification by transition radiation - concentrates on the important forward cone. The RTD (Rear Tracking Detector) provides accurate angle measurement of the recoil electron and the vertex detector (VXD) aims to find particles from heavy flavour decay. To measure momentum accurately the CTD sits in a high magnetic field (B=1,8 T) within the ZEUS calorimeter. (orig./HSI)

  2. Legal and actual central bank independence

    OpenAIRE

    Artha, I.K.D.S.; J. de Haan

    2010-01-01

    Indicators of central bank independence (CBI) based on the interpretation central bank laws in place may not capture the actual independence of the central bank. This paper develops an indicator of actual independence of the Bank Indonesia (BI), the central bank of Indonesia, for the period 1953-2008 and compares it with a new legal CBI indicator based on Cukierman (1992). The indicator of actual independence captures institutional and economic factors that affect CBI. We find that before 199...

  3. Accountability of central banks: aspects and quantification

    Directory of Open Access Journals (Sweden)

    J. DE HAAN

    1999-06-01

    Full Text Available The work examines the relationship between central bank independence and accountability. The authors do this by using an indicator for central bank accountability based on the laws of 16 central banks. Central bank accountability is identified as having three distinct features, namely, the explicit definition and ranking of the objectives of monetary policy, the transparency of the actual monetary policy, and the final responsibility to monetary policy.

  4. Distributed trace using central performance counter memory

    Science.gov (United States)

    Satterfield, David L.; Sexton, James C.

    2013-01-22

    A plurality of processing cores, are central storage unit having at least memory connected in a daisy chain manner, forming a daisy chain ring layout on an integrated chip. At least one of the plurality of processing cores places trace data on the daisy chain connection for transmitting the trace data to the central storage unit, and the central storage unit detects the trace data and stores the trace data in the memory co-located in with the central storage unit.

  5. Centralized database for interconnection system design. [for spacecraft

    Science.gov (United States)

    Billitti, Joseph W.

    1989-01-01

    A database application called DFACS (Database, Forms and Applications for Cabling and Systems) is described. The objective of DFACS is to improve the speed and accuracy of interconnection system information flow during the design and fabrication stages of a project, while simultaneously supporting both the horizontal (end-to-end wiring) and the vertical (wiring by connector) design stratagems used by the Jet Propulsion Laboratory (JPL) project engineering community. The DFACS architecture is centered around a centralized database and program methodology which emulates the manual design process hitherto used at JPL. DFACS has been tested and successfully applied to existing JPL hardware tasks with a resulting reduction in schedule time and costs.

  6. Central bank independence and inflation revisited

    NARCIS (Netherlands)

    Klomp, Jeroen; de Haan, Jakob

    2010-01-01

    We re-examine the relationship between central bank independence (CBI), proxied by the central bank governor's turnover rate and an indicator based on central bank laws in place, and inflation using a random coefficient model with the Hildreth-Houck estimator for more than 100 countries in the perio

  7. Accountability of Central Banks : Aspects and Quantification

    NARCIS (Netherlands)

    de Haan, J.; Amtenbrink, F.; Eijffinger, S.C.W.

    1998-01-01

    This paper starts with a discussion of the various aspects of accountability of central banks. On the basis of this discussion we construct an indicator for accountability for 16 central banks, including the European Central Bank. It is shown that the degree of accountability differs considerably an

  8. "Christofest" New Yorgi Central Parkis / Rael Artel

    Index Scriptorium Estoniae

    Artel, Rael, 1980-

    2004-01-01

    12. II 2005. a. avatakse Christo ja Jeanne-Claude'i keskkonnainstallatsioon "The Gates" New Yorgi Central Parkis. Paralleelselt toimub Metropolitan Muuseumis näitus "Christo and Jeanne-Claude : The Gates, Central Park, New York", kus eksponeeritakse Central Parki installatsiooni ettevalmistavaid materjale: joonistusi, diagramme, fotosid jne

  9. Effect of Compost Application on Some Properties of a Volcanic Soil from Central South Chile Efecto de la Aplicación de Compost sobre Algunas Propiedades de un Suelo Volcánico de La Región Centro-Sur de Chile

    Directory of Open Access Journals (Sweden)

    Pedro José Valarini

    2009-09-01

    Full Text Available Soil compost application is a common soil management practice used by small farmers of Central-South Chile that produces positive effects on soil properties and also promotes presence and activity of arbuscular mycorrhizal fungi (AMF. This fungi form symbiosis with plant roots improving plant nutrition, as well as producing glomalin, a glycoprotein that has been associated with soil aggregation stability. Therefore, the aim of this study was to evaluate, in an Ultisol from Central-South Chile, the effect of different doses of compost on some soil characteristics at the end of the third year of a crop sequence including wheat (Triticum aestivum L., bean (Phaseolus vulgaris L., and grassland (Lolium multiflorum Lam. associated with Trifolium repens L.. Studied soil characteristics included chemical (pH, available-P, organic C, biological (C and N biomass, AMF spore number, root colonization percentage, mycelium length, and glomalin content, as well as physical parameters (water holding capacity [WHC], and water stable aggregates [WSA]. Results showed that, in general, compost application increased soil pH, mycorrizal roots, mycelium length, glomalin levels, and WSA. Significant relationships were found between C and N biomass, C biomass and WSA, C biomass and glomalin, WSA and WHC, among others. Results suggest that compost application to this type of soil is a feasible option as a fertilizer substitute, and a way to avoid soil erosion by small local farmers involved in organic agriculture.La aplicación de compost al suelo, práctica habitual en predios de pequeños agricultores de la región centro-sur de Chile, produce efectos positivos en sus propiedades y promueve la presencia y actividad de los hongos micorrícicos arbusculares (AMF. Estos hongos forman simbiosis con las raíces de las plantas mejorando su nutrición y además producen una glicoproteína llamada glomalina, la cual ha sido relacionada con la estabilidad de los agregados de

  10. Central and forward tracking collaboration

    International Nuclear Information System (INIS)

    The goal of this subsystem R ampersand D project is to carry out a detailed study and design of a complete wire chamber tracking system covering pseudorapidity |η| ≤ 2.5 in a solenoidal detector for the SSC. Most of our group are now part of the Solenoidal Detector Collaboration (SDC), so the work has evolved into developing a tracking system conceptual design for the SDC detector. The design discussed in this report uses straw tube drift chambers for the central tracking region. Because of the high rates in the SSC environment, a small cell design is needed for wire chambers in the central region. Straw tubes as small cells offer many advantages because the sense wire is enclosed in a continuous cathode, and the wire tension due to the sense wire only can be supported without a massive structure. The straw tubes are grouped together to form superlayers in order to provide local track segments. The superlayers are composed of modules consisting of about two hundred straw tubes enclosed in a carbon fiber composite shell. Straw tubes have been used in previous experiments for small vertex drift chambers. However, they have never before been used for a large tracking system

  11. Precipitation chemistry in central Amazonia

    Science.gov (United States)

    Andreae, M. O.; Talbot, R. W.; Berresheim, H.; Beecher, K. M.

    1990-01-01

    Rain samples from three sites in central Amazonia were collected over a period of 6 weeks during the 1987 wet season and analyzed for ionic species and dissolved organic carbon. A continuous record of precipitation chemistry and amount was obtained at two of these sites, which were free from local or regional pollution, for a time period of over 1 month. The volume-weighted mean concentrations of most species were found to be about a factor of 5 lower during the wet season compared with previous results from the dry season. Only sodium, potassium, and chloride showed similar concentrations in both seasons. When the seasonal difference in rainfall amount is taken into consideration, the deposition fluxes are only slightly lower for most species during the wet season than during the dry season, again with the exception of chloride, potassium, and sodium. Sodium and chloride are present in the same ratio as in sea salt; rapid advection of air masses of marine origin to the central Amazon Basin during the wet season may be responsible for the observed higher deposition flux of these species. Statistical analysis suggests that sulfate is, to a large extent, of marine (sea salt and biogenic) origin, but that long-range transport of combustion-derived aerosols also makes a significant contribution to sulfate and nitrate levels in Amazonian rain. Organic acid concentrations in rain were responsible for a large fraction of the observed precipitation acidity; their concentration was strongly influenced by gas/liquid interactions.

  12. Central Equatorial Pacific Experiment (CEPEX)

    Energy Technology Data Exchange (ETDEWEB)

    1993-01-01

    The Earth's climate has varied significantly in the past, yet climate records reveal that in the tropics, sea surface temperatures seem to have been remarkably stable, varying by less than a few degrees Celsius over geologic time. Today, the large warm pool of the western Pacific shows similar characteristics. Its surface temperature always exceeds 27[degree]C, but never 31[degree]C. Heightened interest in this observation has been stimulated by questions of global climate change and the exploration of stabilizing climate feedback processes. Efforts to understand the observed weak sensitivity of tropical sea surface temperatures to climate forcing has led to a number of competing ideas about the nature of this apparent thermostat. Although there remains disagreement on the processes that regulate tropical sea surface temperature, most agree that further progress in resolving these differences requires comprehensive field observations of three-dimensional water vapor concentrations, solar and infrared radiative fluxes, surface fluxes of heat and water vapor, and cloud microphysical properties. This document describes the Central Equatorial Pacific Experiment (CEPEX) plan to collect such observations over the central equatorial Pacific Ocean during March of 1993.

  13. Sede central de una compañía de seguros Oberursel/Ts. - Alemania Federal

    Directory of Open Access Journals (Sweden)

    Hentrich, Helmut

    1977-02-01

    Full Text Available This building is designed to house the control Centre of an Insurance Company, formed by three chartered companies, in the town of Oberursel, near Frankfurt. The work includes seven floors and two basements, in the shape of a swastika, and is completed with a rectangular annex, with two storeys, intended for the restaurant, cafeteria and an all-purpose room. The main building provides offices of a landscape type, with a total of 1,500 jobs, to be extended to 2,500. The structure is in reinforced concrete, with a modulation between support axes of 10.50 X 10.50 m. The stability of the unit is achieved through a main bracing nucleus, which also acts as a vertical communication axis. The frontage is of curtain wall, with steel framework corridor on all the floors, aluminium carpentry and insulating glazing. These corridors lead to two fire scapes, backing on to the main building on opposite sides. Suitable decoration, together with the specially chosen furniture and the varied series of installations, both generic and specific, for this type of centers, contribute towards achieving the suitable working atmosphere. Furthermore, a group of social, recreative and sports installations, facilitate personal contacts among employees.Este edificio se destina a albergar el Centro de control de una compañía de seguros, integrada por tres sociedades anónimas, en la ciudad de Oberursel, cerca de Frankfurt. La obra se desarrolló en seis plantas y dos sótanos con forma de cruz gamada, y se completa con un anexo rectangular, de dos plantas, dedicado a restaurante, cafetería y sala polivalente. El edificio principal distribuye oficinas de tipo paisajístico con un total de 1.500 puestos de trabajo, ampliables hasta 2.500. La estructura es de hormigón armado, con una modulación entre ejes de soportes de 10,50 x 10,50 m. La estabilidad del conjunto se consigue mediante un núcleo central de arriostramiento, que sirve, además, de eje de

  14. Glial involvement in trigeminal central sensitization

    Institute of Scientific and Technical Information of China (English)

    Yu-feng XIE

    2008-01-01

    Recent studies have indicated that trigeminal neurons exhibit central sensitization, an increase in the excitability of neurons within the central nervous system to the extent that a normally innocuous stimulus begins to produce pain after inflamma-tion or injury, and that glial activities play a vital role in this central sensitization. The involvement of glial cells in trigeminal central sensitization contains multiple mechanisms, including interaction with glutamatergic and purinergic receptors. A better understanding of the trigeminal central sensitization mediated by glial cells will help to find potential therapeutic targets and lead to developing new analge-sics for orofacial-specific pain with higher efficiency and fewer side-effects.

  15. Central Solenoid Insert Technical Specification

    Energy Technology Data Exchange (ETDEWEB)

    Martovetsky, Nicolai N [ORNL; Smirnov, Alexandre [ORNL

    2011-09-01

    The US ITER Project Office (USIPO) is responsible for the ITER central solenoid (CS) contribution to the ITER project. The Central Solenoid Insert (CSI) project will allow ITER validation the appropriate lengths of the conductors to be used in the full-scale CS coils under relevant conditions. The ITER Program plans to build and test a CSI to verify the performance of the CS conductor. The CSI is a one-layer solenoid with an inner diameter of 1.48 m and a height of 4.45 m between electric terminal ends. The coil weight with the terminals is approximately 820 kg without insulation. The major goal of the CSI is to measure the temperature margin of the CS under the ITER direct current (DC) operating conditions, including determining sensitivity to load cycles. Performance of the joints, ramp rate sensitivity, and stability against thermal or electromagnetic disturbances, electrical insulation, losses, and instrumentation are addressed separately and therefore are not major goals in this project. However, losses and joint performance will be tested during the CSI testing campaign. The USIPO will build the CSI that will be tested at the Central Solenoid Model Coil (CSMC) Test Facility at the Japan Atomic Energy Agency (JAEA), Naka, Japan. The industrial vendors (the Suppliers) will report to the USIPO (the Company). All approvals to proceed will be issued by the Company, which in some cases, as specified in this document, will also require the approval of the ITER Organization. Responsibilities and obligations will be covered by respective contracts between the USIPO, called Company interchangeably, and the industrial Prime Contractors, called Suppliers. Different stages of work may be performed by more than one Prime Contractor, as described in this specification. Technical requirements of the contract between the Company and the Prime Contractor will be covered by the Fabrication Specifications developed by the Prime Contractor based on this document and approved by

  16. Performance contracting in central government in Denmark

    DEFF Research Database (Denmark)

    Kristiansen, Mads Bøge

    2015-01-01

    for maintaining the MBOR system including setting requirements and recommendations for the design and use of performance contracts, which means that a common central government framework for performance contracting exists. Despite of this common framework, differences in the contract content (scale and focus......This paper looks into performance contracting in Danish central government. Management by Objectives and Results (MBOR) was adopted in central government in Denmark during the 1980s and early 1990s. In 1991, performance contracts between parent ministries and their agencies were introduced...... in Danish central government. Since their introduction, performance contracts have become central elements in the steering and management of agencies in central government in Denmark, and today they are nearly universally adopted in central government. In Denmark, the Ministry of Finance is responsible...

  17. 76 FR 22746 - Wiregrass Central Railway, LLC-Acquisition and Operation Exemption-Wiregrass Central Railroad...

    Science.gov (United States)

    2011-04-22

    ... Surface Transportation Board Wiregrass Central Railway, LLC--Acquisition and Operation Exemption--Wiregrass Central Railroad Company, Inc. Wiregrass Central Railway, LLC (WCR), a noncarrier, has filed a verified notice of exemption under 49 CFR 1150.31 to acquire from Wiregrass Central Railroad Company,...

  18. WINE MARKETS IN CENTRAL EUROPE

    Directory of Open Access Journals (Sweden)

    Š BOJNEC

    2007-04-01

    Full Text Available This paper analyses the tendencies of grapes growing, wine trading and wine price competitiveness in Central European region. Croatia is net exporter of wines, Hungary is net exporter of grapes and wines, and Austria, Slovakia, and Slovenia are net importers of grapes and wines. Reductions in vineyards and increase in yields are found for Austria, Hungary, and Slovakia. More stable developments in vineyards, but decline in yields, are found for Croatia and Slovenia. Grape production increases in Austria, remains stable in Croatia, explores annual oscillations in Hungary, and declines in Slovakia and Slovenia. Export-to-import wine prices deteriorate for Austria and Hungary with most recent stabilization and price similarity, which hold also for Slovakia. Slovenian export-to-import wine prices are unstable, while Croatia experiences a bit higher export than import wine prices. Wine marketing, wine brand image of quality, and wine tourism are seen as tools to improve competitiveness in the wine sector.

  19. Centralized Allocation in Multiple Markets

    DEFF Research Database (Denmark)

    Monte, Daniel; Tumennasan, Norovsambuu

    The problem of allocating indivisible objects to different agents, where each indi vidual is assigned at most one object, has been widely studied. Pápai (2000) shows that the set of strategy-proof, nonbossy, Pareto optimal and reallocation-proof rules are hierarchical exchange rules | generalizat......The problem of allocating indivisible objects to different agents, where each indi vidual is assigned at most one object, has been widely studied. Pápai (2000) shows that the set of strategy-proof, nonbossy, Pareto optimal and reallocation-proof rules are hierarchical exchange rules...... | generalizations of Gale's Top Trading Cycles mechanism. We study the centralized allocation that takes place in multiple markets. For example, the assignment of multiple types of indivisible objects; or the assignment of objects in successive periods. We show that the set of strategy-proof, Pareto efficient...

  20. Central solar-energy receiver

    Science.gov (United States)

    Not Available

    1981-10-27

    An improved tower-mounted central solar energy receiver for heating air drawn through the receiver by an induced draft fan is described. A number of vertically oriented, energy absorbing, fin-shaped slats are radially arranged in a number of concentric cylindrical arrays on top of the tower coaxially surrounding a pipe having air holes through which the fan draws air which is heated by the slats which receive the solar radiation from a heliostat field. A number of vertically oriented and wedge-shaped columns are radially arranged in a number of concentric cylindrical clusters surrounding the slat arrays. The columns have two mirror-reflecting sides to reflect radiation into the slat arrays and one energy absorbing side to reduce reradiation and reflection from the slat arrays.

  1. Central Exclusive Production at LHCb

    CERN Document Server

    McNulty, Ronan

    2016-01-01

    Central Exclusive Production (CEP) is a unique process at hadron machines in which particles are produced via colourless propagators. LHCb have measured the cross-sections for the CEP of vector mesons, $J/\\psi,\\psi(2S),\\Upsilon(1S),\\Upsilon(2S)$ and $\\Upsilon(3S)$, which are photo-produced. In the double pomeron exchange process, preliminary measurements have been made of $\\chi_{c0},\\chi_{c1}, \\chi_{c2}$ meson production while the first observations of the CEP of pairs of charmonia, $J/\\psi J/\\psi$ and $J/\\psi \\psi(2S)$, have been made and limits obtained on the pair production of other charmonia.

  2. CST-01-Central Standard Timing

    Institute of Scientific and Technical Information of China (English)

    2013-01-01

    薄如蝉翼名为CentralStandardTiming的工作室推出了E—ink材质代号为CST-01的手表,其厚度仅为0.8mm,号称全球最薄。一次充电10分钟便可连续使用15年。该手表屏幕由多层柔性材料构成。整体十分轻巧并且可弯曲,腕带则采用了柔性不锈钢材质。CST-01的预售价格为129美元。约合人民币800元,目前已经在著名的集资网站Kickstarter上创建项目。

  3. Wooden Calendars from Central Rhodopes

    Science.gov (United States)

    Koleva, V.

    2008-10-01

    Four wooden calendars from the village of Polkovnik Serafimovo, Smolyan region, in the Central Rhodopes are presented here, and three of them - for the first time. The shape and size, the kind of the signs and structure of the calendar record bear the characteristic features of the rest of the Bulgarian wooden calendars. The short notches on the edges represent the days of the year in the Julian (solar) calendar. The special signs on the sides mark the fixed festivals of the Orthodox Church calendar and are also influenced by the local tradition. The type of the signs confirms that the wooden sticks belong to the group of calendars from the Central Rhodopes. According to the beginning date of the calendar record on the sticks, two of the calendars are of the April (May) or October (November) type which corresponds to the very popular economic division of the year in the folk calendar into two periods -- warm and cold. The other two sticks, which are very similar to each other, make an exception in this respect among the rest of the Bulgarian wooden calendars. The months are divided into four groups (seasons) on each of the four edges of the stick (only one calendar from Burgas region has the same structure). The most interesting thing about the two sticks is that this is the only case among all known Bulgarian calendars that the beginning of the calendar record coincides with the beginning of the civil year on 1st January (January type) like some wooden calendars from Western Europe. Nowadays it is getting harder and harder to find wooden calendars in Bulgaria and in the neighbouring Balkan countries. The thorough knowledge about them could be helpful in various scientific fields, e.g. history of religion, ethnology, history of astronomy and mathematics, as well as semiotics.

  4. Application of 6S management in management of disposable sterile goods warehouse of central sterile supply department%6S 管理在消毒供应中心一次性无菌物品仓库管理中的应用

    Institute of Scientific and Technical Information of China (English)

    饶冬霞; 彭晓珍; 庞明月; 刘会芬; 喻征群; 熊晓云

    2015-01-01

    of SPSS 13 .0 software .RESULTS The intact rate of goods of the 6S group was 99 .9% ,the qualified rate of personnel's operation 99 .8% ,the compliance rate of goods 100 .0% ;the complaint to department was zero . The management quality of the disposable aseptic goods and the effect of quality control were significantly im-proved .The management of the warehouse was conducted in an orderly way ,and the staff took the goods more quickly .The time of receiving 100 goods was 50 .0% shortened ,and the goods were accurately issued ;there was significant difference before and after the implementation of 6S management (P<0 .05) .CONCLUSION The appli-cation of the 6S management has improved the quality of management of the disposable sterile goods warehouse of central sterile supply department ,ensured the safety of use of the disposable sterile goods in clinical departments , and raise the work efficiency and comprehensive competence of the staff .It is feasible .

  5. Groundwater hydrogeochemistry of Trikala municipality, central Greece.

    Science.gov (United States)

    Skordas, Konstantinos; Papastergios, Georgios; Tziantziou, Lamprini; Neofitou, Nikolaos; Neofitou, Christos

    2013-01-01

    Sixty-four samples from the groundwater resources of Trikala municipality, central Greece, were collected during two periods (2006 and 2007) and analyzed for physico-chemical parameters (temperature, pH, specific electrical conductivity, and total dissolved solids), major ions (Ca(2+), Cl(-), HCO(3)(-), K(+), Mg(2+), Na(+), NO(3)(-), SO(4)(2-)), and several potentially toxic elements (Al, B, Ba, Br, Ca, Ce, Cl, Cr, Cu, Fe, K, La, Li, Mg, Mn, Mo, Na, Nd, Ni, P, Pb, Rb, S, Sc, Si, Sn, Sr, U, V, Y, Zn). European Council directives and USEPA guidelines were used to assess the water quality. The results indicate that all samples are fresh water, suitable for human consumption. All basic ions and physico-chemical parameters have average concentrations below their recommended optimum limits with the exception of electrical conductivity, for January 2007, and nitrate for October 2006 and January 2007 sampling periods. This exceedance is the result of dissolution of minerals such as calcite and dolomite that are present in the surrounding rocks and the application of fertilizers, respectively. Lead is the only element with an average value that exceeds the recommended EC guideline, while special attention should be paid to one borehole (T9) which has elevated NO(3)(-) values which may pose a risk to human health. PMID:22282351

  6. Desarrollo y aplicación del diagnóstico y pronóstico técnico al mantenimiento de los sistemas centralizados de aire acondicionado // Develop and application of the diagnosis and technical prediction to the maintenance of the centralized systems of conditi

    Directory of Open Access Journals (Sweden)

    J. L. Sánchez Ávila

    2000-10-01

    Full Text Available Se expone la aplicación del mantenimiento por diagnóstico y pronóstico técnico al sistema centralizado de aireacondicionado con recuperación del calor del hotel LTI Bella Costa; como solución a los graves problemas a que seenfrenta la dirección de servicios técnicos de las instalaciones turísticas para realizar un mantenimiento con calidad y a unmenor costo.El desarrollo de un plan experimental, en las instalaciones del hotel, permitió obtener las curvas que expresan elcomportamiento de la degradación de estos sistemas en el tiempo, así como determinar el momento más oportuno para larealización del mantenimiento.La aplicación de esta investigación permitió la implementación de un mantenimiento menos costoso y de más calidad,aumentando la rentabilidad de la labor del mantenimiento, y lo que es decisivo en este tipo de instalación: la seguridad en laexplotación como garantía de un servicio sin fallas.Palabras claves: mantenimiento, refrigeración, predictivo, diagnóstico, pronóstico.____________________________________________________________________Abstract:In this paper is exposed the application of the maintenance by diagnosis and technical prediction to the centralized systemof air conditioned with heat recovery of the hotel Beautiful LTI Costa; as a solution to the serious problems that thetechnical management services faces in the tourist facilities to carry out a maintenance with quality and whith smaller cost.The development of an experimental plan, in the hotel facilities, allowed to obtain the curves that express the behavior ofthe degradation of these systems in the time, as well as to determine the most opportune moment for the realization of themaintenance.The application of this investigation allowed the implementation of a less expensive maintenance and of more quality,increasing the profitability of the maintenance work, and what is decisive in this installation type: the security in theexploitation as a

  7. Desarrollo y aplicación del diagnóstico y pronóstico técnico al mantenimiento de los sistemas centralizados de aire acondicionado. // Develop and application of diagnosis and technical prediction to maintenance of centralized air conditioned systems.

    Directory of Open Access Journals (Sweden)

    J. L. Sánchez Ávila

    2001-10-01

    Full Text Available Se expone la aplicación del mantenimiento por diagnóstico y pronóstico técnico al sistema centralizado de aireacondicionado con recuperación del calor del hotel LTI Bella Costa; como solución a los graves problemas a que seenfrenta la dirección de servicios técnicos de las instalaciones turísticas para realizar un mantenimiento con calidad y a unmenor costo. El desarrollo de un plan experimental, en las instalaciones del hotel, permitió obtener las curvas que expresanel comportamiento de la degradación de estos sistemas en el tiempo, así como determinar el momento más oportuno para larealización del mantenimiento.La aplicación de esta investigación permitió la implementación de un mantenimiento menoscostoso y de más calidad, aumentando la rentabilidad de la labor del mantenimiento, y lo que es decisivo en este tipo deinstalación: la seguridad en la explotación como garantía de un servicio sin fallas.Palabras claves: Mantenimiento, refrigeración, predictivo, diagnóstico, pronóstico.___________________________________________________________________Abstract:The application of maintenance by diagnosis and technical prediction to centralized system of conditioned air withrecovery of heat is exposed; as solution to the serious problems faces technical services of tourist facilities to carry outmaintenance with quality and smaller cost. The development of an experimental plan, in hotel facilities, allowed to obtaincurves that express the behavior of degradation of these systems in time, as well as to determine the most opportunemoment for the maintenance realization. Application of this investigation allowed the implementation of a less expensivemaintenance with more quality, increasing the profitability of maintenance work, and what is decisive in this type ofinstallation,: the security in the exploitation like guarantee of a service without flaws.Key words. Maintenance, refrigeration, prediction, diagnosis, air conditioned.

  8. Hirsch index as a network centrality measure

    CERN Document Server

    Campiteli, Monica G; Soles, Paulo R C; Soares, Leonardo H D; Kinouchi, Osame

    2010-01-01

    We study the h Hirsch index as a local node centrality measure for complex networks in general. The h index is compared with the Degree centrality (a local measure), the Betweenness and Eigenvector centralities (two non-local measures) in the case of a biological network (Yeast interaction protein-protein network) and a linguistic network (Moby Thesaurus II) as test environments. In both networks, the Hirsch index has poor correlation with Betweenness centrality but correlates well with Eigenvector centrality, specially for the more important nodes that are relevant for ranking purposes, say in Search Machine Optimization. In the thesaurus network, the h index seems even to outperform the Eigenvector centrality measure as evaluated by simple linguistic criteria.

  9. Reduced central blood volume in cirrhosis

    DEFF Research Database (Denmark)

    Bendtsen, F; Henriksen, Jens Henrik Sahl; Sørensen, T I;

    1989-01-01

    The pathogenesis of ascites formation in cirrhosis is uncertain. It is still under debate whether the effective blood volume is reduced (underfilling theory) or whether the intravascular compartment is expanded (overflow theory). This problem has not yet been solved because of insufficient tools...... for measuring the central blood volume. We have developed a method that enables us to determine directly the central blood volume, i.e., the blood volume in the heart cavities, lungs, and central arterial tree. In 60 patients with cirrhosis and 16 control subjects the central blood volume was assessed according...... to the kinetic theory as the product of cardiac output and mean transit time of the central vascular bed. Central blood volume was significantly smaller in patients with cirrhosis than in controls (mean 21 vs. 27 ml/kg estimated ideal body weight, p less than 0.001; 25% vs. 33% of the total blood volume, p less...

  10. Transpleural central venous catheter discovered during thoracotomy

    Directory of Open Access Journals (Sweden)

    Ashima Malhotra

    2014-01-01

    Full Text Available We report an uncommon complication of subclavian central venous catheterization, discovered at thoracotomy. The central venous catheter (CVC was placed by left infraclavicular route after induction of general anesthesia. CVC was secured after aspiration of blood and satisfactory central venous tracing. On thoracotomy, CVC was noticed to traverse the pleural cavity while the tracing was normal. CVC was thus removed consequent to which bleeding from each puncture site was noticed, that were secured surgically.

  11. Central sleep apnea – a case report

    OpenAIRE

    Dybala Andrzej; Dyczko Monika; Makaruk Boguslaw; Kicinski Pawel; Bartoszek Elzbieta; Myslinski Wojciech; Rahnama Mansur; Mosiewicz Jerzy

    2014-01-01

    Central sleep apnea (CSA) is a disease characterized by repetitive episodes of the socalled central apneas during sleep. The disease has a very complex etiology. In clinical practice, the most important causes of CSA are disorders of the central nervous system, congestive heart failure or certain pathological changes of the respiratory muscles. We present a case of a 43-year-old male with severe CSA, who was successfully treated with BiPAP ST equipment.

  12. Central sleep apnea – a case report

    Directory of Open Access Journals (Sweden)

    Dybala Andrzej

    2014-06-01

    Full Text Available Central sleep apnea (CSA is a disease characterized by repetitive episodes of the socalled central apneas during sleep. The disease has a very complex etiology. In clinical practice, the most important causes of CSA are disorders of the central nervous system, congestive heart failure or certain pathological changes of the respiratory muscles. We present a case of a 43-year-old male with severe CSA, who was successfully treated with BiPAP ST equipment.

  13. Central Neurogenic Respiratory Failure: A Challenging Diagnosis

    OpenAIRE

    Carvalho, Flávio A.; Bernardino, Tenille; Maciel, Ricardo O.H.; Felizola, Sérgio F.A.; Costa, Eduardo L.V.; Silva, Gisele S

    2011-01-01

    Background Central nervous system lesions are rare causes of respiratory failure. Simple observation of the breathing pattern can help localize the lesion, but the examiner needs to be aware of potential pitfalls such as metabolic or pulmonary alterations. Methods We describe 3 cases in which central neurogenic respiratory failure occurred simultaneously with other alterations or in an unusual presentation. Results All patients were diagnosed with central neurogenic respiratory failure and tr...

  14. Transparency in Central Bank Financial Statement Disclosures

    OpenAIRE

    Kenneth Sullivan

    2000-01-01

    The IMF's development of the Code of Good Practices on Transparency in Monetary and Financial Policies and the introduction of safeguards assessments have increased emphasis on transparency of the disclosures made in central bank financial statements. This paper, which updates WP/00/186, looks at the disclosure requirements for central banks under International Financial Reporting Standards and provides practical guidance for those responsible for preparing central bank financial statements.

  15. On the Central Coefficients of Riordan Matrices

    OpenAIRE

    Barry, Paul

    2013-01-01

    We use the Lagrange-Bürmann inversion theorem to characterize the generating function of the central coefficients of the elements of the Riordan group of matrices. We apply this result to calculate the generating function of the central elements of a number of explicit Riordan arrays, defined by rational expressions, and in two cases we use the generating functions thus found to calculate the Hankel transforms of the central elements, which are themselves expressible as combinatorial polynomi...

  16. Clarity of Central Bank Communication About Inflation

    OpenAIRE

    Ales Bulir; David-Jan Jansen; Martin Cihak

    2011-01-01

    This paper examines whether the clarity of central bank communication about inflation has changed with the economic environment. We use readability statistics and content analysis to study the clarity of communication on the inflation outlook by seven central banks between 1997 and 2010. Overall, we find no strong indications that central banks were less clear in explaining their policies when faced with higher uncertainty or a less favorable inflation outlook. The global financial crisis, ho...

  17. 2. The Central American gang phenomenon

    OpenAIRE

    Does, Antonia

    2013-01-01

    2.1. Differentiating between pandillas and maras Youth gangs have existed since the 1960s and 1970s in Central America. However, there are different types of Central American gangs and thus one has to distinguish between pandillas and maras. The former are localized, homegrown gangs, which are “direct inheritors” (Jütersonke, Rodgers & Muggah 2009: 379) of the gangs that have historically characterized Central American societies, while the latter are a more recent phenomenon with transnationa...

  18. Urban history and modernity in Central Europe

    OpenAIRE

    Klautke, E. F.

    2010-01-01

    This historiographical review discusses recent literature on cities in modern Central Europe – mainly on Berlin and Vienna – which reflects the great variety of approaches to urban history and underlines the importance of urban history for the study of modernity. The history of urbanisation was a central event in the history of modernity. Especially in the Central European capitals of Berlin and Vienna, where modernisation and urban growth started later and then advanced quicker than in West ...

  19. Central nervous system tuberculosis: MRI

    International Nuclear Information System (INIS)

    The MRI findings of 18 proven cases of central nervous system (CNS) tuberculosis were reviewed; 10 patients were seropositive for HIV. All had medical, laboratory, or surgical proof of CNS tuberculosis. Eleven patients had meningitis, of whom two also had arachnoiditis. Five patients had focal intra-axial tuberculomas: four brain masses and one an intramedullary spinal lesion. Two patients had focal extra-axial tuberculomas: one in the pontine cistern, and one in the spine. In all 11 patients with meningitis MRI showed diffuse, thick, meningeal enhancement. All intraparenchymal tuberculomas showed low signal intensity on T2-weighted images and ring or nodular enhancement. The extra-axial tuberculomas had areas isointense or hypointense relative to normal brain and spinal cord on T2-weighted images. Although tuberculous meningitis cannot be differentiated from other meningitides on the basis of MR findings, intraparenchymal tuberculomas show characteristic T2 shortening, not found in most other space-occupying lesions. In the appropriate clinical setting, tuberculoma should be considered. (orig.)

  20. Towards a centralized Grid Speedometer

    CERN Document Server

    Gutsche, Oliver

    2013-01-01

    Given the distributed nature of the grid and the way CPU resources are pledged and scared around the globe, VOs are facing the challenge to monitor the use of these resources. For CMS and the operation of centralized workflows the monitoring of how many production jobs are running and pending in the Glidein WMS production pools is very important. The Dashboard SSB (Site Status Board) provides a very flexible framework to collect, aggregate and visualize data. The CMS production monitoring team uses the SSB to define the metrics that have to be monitored and the alarms that have to be set. During the integration of the CMS production monitoring into the SSB, several enhancements to the core functionality of the SSB were implemented; all in a generic way, so that other VOs using the SSB can use them as well. Alongside these enhancements, there were a few changes to the core of the SSB framework from which the CMS production team was able to benefit. We will present the details of the implementation and the adva...