WorldWideScience

Sample records for application central cafeteria

  1. Cafeteria Change

    Science.gov (United States)

    Schroeder, Ken

    2005-01-01

    In this paper, the author discusses an approach that can show today's students how to become more comfortable with a racial or ethnic group different from one's own. "Mix It Up at Lunch" Day calls for students to swap seats in their school cafeterias, break out of their comfort zones, and meet new people. The program originated in 2002 as a way in…

  2. Smartphone app allows online payments in cafeterias on Meyrin site

    CERN Multimedia

    2016-01-01

    As of October 18, 2016, Novae will implement a new additional system of payment in all the cafeterias on the Meyrin site, using the smartphone application Mobino. For step-by-step instructions watch this short video:

  3. Summer season | Cafeteria closures

    CERN Multimedia

    2013-01-01

    Please note the following cafeteria closures over the summer season: Bldg. 54 closed from 29/07/2013 to 06/09/2013. Bldg. 13: closed from 13/07/2013 to 06/09/2013. Restaurant No. 2, table service (brasserie and restaurant): closed from 01/08/2013 to 06/09/2013. Bldg. 864: closed from 29/07/2013 to 06/09/2013. Bldg. 865: closed from 29/07/2013 to 06/09/2013.

  4. Cafeteria/Multi-Purpose Spaces.

    Science.gov (United States)

    Larsen, Christopher W.

    2001-01-01

    Highlights school cafeteria design criteria that creates dining facilities that are both social areas as well as eating spaces. Also examined are key design considerations for multi-purpose areas. (GR)

  5. Field guide to hospital cafeterias.

    Science.gov (United States)

    Smith, R P

    1986-09-01

    We have all faced the problem of whether or not to venture into that gastronomic wasteland known as the hospital cafeteria. Hospital cafeterias have developed a reputation, deserved or otherwise, as less than ideal places to eat. Many people overlook the fact that this is a direct result of trying to provide patient meals that are salt-free, sugar-free, fiber-free, and taste-free. (Some faint traces of color may, occasionally, be found.) How then does one go about choosing whether to venture in, and how does one survive the encounter once there? The following guide has been assembled to help the reader through this difficult process.

  6. School Cafeteria Operations: Separating Myth from Reality

    Science.gov (United States)

    Weeks, Richard

    2011-01-01

    School officials often assume that the food service director or management company should be the one concerned with the cafeteria program's management details. But of course that's not the case. Cafeteria operations affect the school business bottom line, so they indeed fall under the purview of school business officials. Not only should school…

  7. 复合化高校食堂建筑设计初探——中南大学新校区食堂设计%Composite Architectural Design of University Dining Hall——Central South University,New Campus Cafeteria Design

    Institute of Scientific and Technical Information of China (English)

    齐靖

    2011-01-01

    以中南大学新校区食堂设计为例,针对当今高校食堂建筑趋向于多功能复合化这一特点,提出了相应的解决方式,希望可以为该类型建筑设计提供一些借鉴。%for today's college canteen building tend to be multi-functional composite,Take Central South University new campus cafeteria design for example,We put forward the corresponding solutions in this paper,hoping to provide some architectural designs for the type of reference.

  8. Microbiological criteria in public catering: sampling and auditing experiences in canteens and cafeterias in Piedmont

    Directory of Open Access Journals (Sweden)

    Amaranta Traversa

    2013-02-01

    Full Text Available In the period 2006-2011 six public catering establishments (3 canteens and 3 cafeterias were monitored, trough audit and sampling, in order to verify the application of good manufacturing and hygiene practices during food production, handling and serving. The compliance to microbiological food safety criteria (Listeria monocytogenes and Salmonella spp. and process hygiene criteria were investigated using ISO standards for microbiological analyses. A total of 612 samples were collected: 192 food samples and 288 environmental swab samples from canteens; 33 food samples and 99 swab samples from cafeterias. Regarding food safety, two samples were in disagreement with criteria fixed in EU Regulation as Listeria monocytogenes was isolated from a turkey breast in a canteen and from a sandwich in a cafeteria. Regarding process hygiene criteria, as no microbiological limits are legally defined for catering services, for this study limits were fixed according to the quality standards of tender, scientific literature and laboratory experience. 23.4% foodstuffs and 8.7% swabs resulted non-compliant in canteens; 48.5% foodstuffs and 6.1% swabs resulted non-compliant in cafeterias. The count of coagulase-positive staphylococci (CPS was higher of the fixed limits in raw turkey meat and in cooked spinach: the presence among CPS of S. aureus was confirmed, strains were not able to produce enterotoxins. The most common non-compliance in hygiene criteria was represented by aerobic colony count (60.7% of total non-compliance in canteens and 75.0% in cafeterias and coliform bacteria (20.3% in canteens and 25.0% in cafeterias. Nine raw foods or raw readyto- eat food samples were non-compliant for both coliform bacteria and aerobic count; one sample (raw turkey meat was non-compliant for CPS and aerobic count but resulted to be compliant after cooking. Auditing and sampling are the most effective tools to improve food quality standard and to enhance food business

  9. Application of Cafeteria Total Rewards in the Incentive of Professional Managers In Ruraf Financial System%自助式整体薪酬在农信系统职业经理人激励中的应用

    Institute of Scientific and Technical Information of China (English)

    栾凌雁; 陈锦新

    2012-01-01

    According to the problems in the incentive of professional managers in rural financial system as well as the characteristics of the professional managers themselves, the characteristics and advantages of cafeteria total rewards in the incentive of professional managers were studied, based on which the practical implementation and issues we should pay attention to of the cafeteria total rewards were brifely analyzed.%从现行农信系统职业经理人激励中存在的问题入手,结合职业经理人自身的特点,对自助式整体薪酬在职业经理人激励中的特点和优点进行了研究,在此基础上,对自助式整体薪酬的具体实施和应注意的问题进行了简要分析.

  10. Digital Photography as a Tool to Measure School Cafeteria Consumption

    Science.gov (United States)

    Swanson, Mark

    2008-01-01

    Background: Assessing actual consumption of school cafeteria meals presents challenges, given recall problems of children, the cost of direct observation, and the time constraints in the school cafeteria setting. This study assesses the use of digital photography as a technique to measure what elementary-aged students select and actually consume…

  11. Bye Bye Cafeteria, Hello Restaurant-Style Dining.

    Science.gov (United States)

    Milshtein, Amy

    1999-01-01

    Examines how the university cafeteria is being transformed into restaurant-style dining to attract and retain sophisticated student customers. Harvard's and Seattle Pacific University's dining facilities are briefly highlighted. Concluding comments address planning tips for converting the old cafeteria into a better dining experience. (GR)

  12. Application of the Balanced Score Card in the Management of Cafeterias of College%浅谈平衡计分卡在高校食堂管理中的运用

    Institute of Scientific and Technical Information of China (English)

    王兴伯

    2014-01-01

    The balanced score card is a kind of efficient instrument for the performance evaluation. More and more for-profit ventures use the balanced score cards to improve the management level of the ventures. With the economic development, the socialized reform of the university logistics gradually changes into operating. Cafeterias management changes into the enterprise model, but it still keeps the characteristic of service first. So, the non-financial indicator is particularly important. This paper introduces the balanced score card as the new way to evaluate the performance of the cafeterias management in college, establishes a comprehensive evaluation index system and analyzes the problems should pay attention to in the construction of the cafeterias management of college to ensure the profit targets on the basis of the high quality service.%平衡计分卡是绩效考核的一种有效工具,越来越多的营利性企业青睐于使用平衡计分卡提高企业管理水平。随着经济发展,高校后勤的社会化改革逐渐向经营性转变,食堂经营向企业模式转变,但依然保持服务性第一的特点,非财务指标显得尤为重要。文章引入平衡计分卡作为高校食堂绩效考核的新途径,建立综合评价指标体系,并分析在高校食堂管理中实施需要注意的问题,以达成高校食堂总愿景,即在保证优质服务的基础上完成营利目标。

  13. 36 CFR 1280.68 - May I use the cafeterias?

    Science.gov (United States)

    2010-07-01

    ... 36 Parks, Forests, and Public Property 3 2010-07-01 2010-07-01 false May I use the cafeterias... the Washington, DC, Area? § 1280.68 May I use the cafeterias? Yes, the Charters Café in the National Archives Building is normally open to the public Monday through Friday, 10 a.m. to 4 p.m. and the...

  14. Cafeteria-Style Grading in General Chemistry

    Science.gov (United States)

    Goodwin, John A.; Gilbert, Brian D.

    2001-04-01

    Self-selected individual course-grade weighting schemes allow students personal choice of course components in the general chemistry sequence at Coastal Carolina University. With the availability of a wide range of commercial and academically produced pedagogical resources, students can select materials that best suit their own learning styles, social situations, and motivation level. Our students use a signed contract to indicate their preferred grade-weighting schemes for determination of the course grade. In doing so, they choose from course components that include peer-led team learning (PLTL) in the Workshop Chemistry (WSC) model, computer-assisted instruction (CAI) using the ChemSkill Builder (CSB) software, a variety of in-class quizzes and group problem-solving exercises, written exams, and the final written exam. Minimum percentage values are required of all components except WSC and CSB, which have been completely optional graded course components at CCU since the summer of 1999. Comparison of student success in the course and content learning suggests that the improvements observed with introduction of a gamut of activities increase even more when the cafeteria-style grading is implemented.

  15. 34 CFR 395.33 - Operation of cafeterias by blind vendors.

    Science.gov (United States)

    2010-07-01

    ... 34 Education 2 2010-07-01 2010-07-01 false Operation of cafeterias by blind vendors. 395.33... BLIND ON FEDERAL AND OTHER PROPERTY Federal Property Management § 395.33 Operation of cafeterias by blind vendors. (a) Priority in the operation of cafeterias by blind vendors on Federal property shall...

  16. 20 CFR 404.1053 - “Qualified benefits” under a cafeteria plan.

    Science.gov (United States)

    2010-04-01

    ... 20 Employees' Benefits 2 2010-04-01 2010-04-01 false âQualified benefitsâ under a cafeteria plan... Wages § 404.1053 “Qualified benefits” under a cafeteria plan. We do not include as wages any qualified benefits under a cafeteria plan as described in section 125 of the Code if such payment would not...

  17. Serving Up Change in School Cafeterias (with Related Video)

    Science.gov (United States)

    Capalbo, Mike A.

    2011-01-01

    Today's education institution kitchens are colorful and inviting, designed with curvature and stainless steel to compete with local restaurants, offering more variety and efficiency to the demanding health-conscious "Generation Me" consumer who is short on time and big on selection. In short, campus eateries are less "cafeteria" and more "cafe."…

  18. Pollution Prevention Opportunity Assessment for the SNL/NM cafeterias.

    Energy Technology Data Exchange (ETDEWEB)

    McCord, Samuel Adam

    2005-12-01

    This Pollution Prevention Opportunity Assessment (PPOA) was conducted for the two Sandia National Laboratories/New Mexico cafeteria facilities between May and August 2005. The primary purpose of this PPOA is to assess waste and resource reduction opportunities and issue Pollution Prevention (P2) recommendations for Sandia's food service facilities. This PPOA contains recommendations for energy, water and resource reduction, as well as material substitution based upon environmentally preferable purchasing. Division 3000 has requested the PPOA report as part of the Division's compliance effort to implement the Environmental Management System (EMS) per DOE Order 450.1. This report contains a summary of the information collected and analyses performed with recommended options for implementation. The SNL/NM P2 Group will work with Division 3000 and the respective cafeteria facilities to implement these options.

  19. Ergonomic assessments of three Idaho National Engineering Laboratory cafeterias

    Energy Technology Data Exchange (ETDEWEB)

    Ostrom, L.T.; Romero, H.A.; Gilbert, B.G.; Wilhelmsen, C.A.

    1993-05-01

    The Idaho National Engineering Laboratory is a Department of Energy facility that performs a variety of engineering and research projects. EG&G Idaho is the prime contractor for the laboratory and, as such, performs the support functions in addition to technical, research, and development functions. As a part of the EG&G Idaho Industrial Hygiene Initiative, ergonomic assessments were conducted at three Idaho National Engineering Laboratory Cafeterias. The purposes of the assessments were to determine whether ergonomic problems existed in the work places and, if so, to make recommendations to improve the work place and task designs. The study showed there were ergonomic problems in all three cafeterias assessed. The primary ergonomic stresses observed included wrist and shoulder stress in the dish washing task, postural stress in the dish washing and food preparation tasks, and back stress in the food handling tasks.

  20. Ergonomic assessments of three Idaho National Engineering Laboratory cafeterias

    Energy Technology Data Exchange (ETDEWEB)

    Ostrom, L.T.; Romero, H.A.; Gilbert, B.G.; Wilhelmsen, C.A.

    1993-01-01

    The Idaho National Engineering Laboratory is a Department of Energy facility that performs a variety of engineering and research projects. EG G Idaho is the prime contractor for the laboratory and, as such, performs the support functions in addition to technical, research, and development functions. As a part of the EG G Idaho Industrial Hygiene Initiative, ergonomic assessments were conducted at three Idaho National Engineering Laboratory Cafeterias. The purposes of the assessments were to determine whether ergonomic problems existed in the work places and, if so, to make recommendations to improve the work place and task designs. The study showed there were ergonomic problems in all three cafeterias assessed. The primary ergonomic stresses observed included wrist and shoulder stress in the dish washing task, postural stress in the dish washing and food preparation tasks, and back stress in the food handling tasks.

  1. Using nudging and social marketing techniques to create healthy worksite cafeterias in the Netherlands: intervention development and study design

    OpenAIRE

    Velema, Elizabeth; Vyth, Ellis L.; Steenhuis, Ingrid H. M.

    2017-01-01

    Background The worksite cafeteria is a suitable setting for interventions focusing on changing eating behavior, because a lot of employees visit the worksite cafeteria regularly and a variety of interventions could be implemented there. The aim of this paper is to describe the intervention development and design of the evaluation of an intervention to make the purchase behavior of employees in the worksite cafeteria healthier. The developed intervention called “the worksite cafeteria 2.0” con...

  2. 26 CFR 54.4980G-5 - HSA comparability rules and cafeteria plans and waiver of excise tax.

    Science.gov (United States)

    2010-04-01

    ... 26 Internal Revenue 17 2010-04-01 2010-04-01 false HSA comparability rules and cafeteria plans and... HSA comparability rules and cafeteria plans and waiver of excise tax. Q-1: If an employer makes contributions through a section 125 cafeteria plan to the HSA of each employee who is an eligible...

  3. 41 CFR 102-74.65 - Are cafeterias authorized under the Randolph-Sheppard Act operated by permit or contract?

    Science.gov (United States)

    2010-07-01

    ... 41 Public Contracts and Property Management 3 2010-07-01 2010-07-01 false Are cafeterias....65 Are cafeterias authorized under the Randolph-Sheppard Act operated by permit or contract? They are... State licensing agency to license blind vendors to operate cafeterias on Federal property....

  4. 41 CFR 102-74.60 - Are Federal agencies required to give blind vendors priority in operating cafeterias?

    Science.gov (United States)

    2010-07-01

    ... required to give blind vendors priority in operating cafeterias? 102-74.60 Section 102-74.60 Public....60 Are Federal agencies required to give blind vendors priority in operating cafeterias? Yes. Federal agencies are required to give Randolph-Sheppard vendors priority in the operation of cafeterias when...

  5. Effect of Coleus forskohliiextract on cafeteria diet-induced obesity in rats

    Directory of Open Access Journals (Sweden)

    Hebbani Nagarajappa Shivaprasad

    2014-01-01

    Full Text Available Background: Obesity is a metabolic disorder that can lead to adverse metabolic effects on blood pressure, cholesterol, triglycerides and insulin resistance and also increases the risk of coronary heart disease, ischemic stroke and type 2 diabetes mellitus. This study was designed to determine the effect of Coleus forskohlii on obesity and associated metabolic changes in rats fed with cafeteria diet. Objective: The aim of this study was to evaluate antiobesogenic and metabolic benefits of C. forskohlii in cafeteria diet induced obesity rat model. Materials and Methods: Rats were randomly divided into five groups of six animals in each group and as follows: Normal pellet diet group; cafeteria diet group; cafeteria diet followed by 50 mg/kg/d Coleus forskohlii extract (CFE, 100 mg/kg/d CFE and 45 mg/kg/d orlistat groups, respectively. Indicators of obesity such as food intake, body weight and alteration in serum lipid profiles were studied. Results: Feeding of cafeteria diet induced obesity in rats. Administration of CFE significantly halted increase in food intake and weight gain associated with cafeteria diet. Development of dyslipidemia was also significantly inhibited. Conclusion: The observed effects validate that supplementation of CFE with cafeteria diet could curb the appetite and mitigate the development of dyslipidemia.

  6. Central station applications planning activities and supporting studies. [application of photovoltaic technology to power generation plants

    Science.gov (United States)

    Leonard, S. L.; Siegel, B.

    1980-01-01

    The application of photovoltaic technology in central station (utility) power generation plants is considered. A program of data collection and analysis designed to provide additional information about the subset of the utility market that was identified as the initial target for photovoltaic penetration, the oil-dependent utilities (especially muncipals) of the U.S. Sunbelt, is described along with a series of interviews designed to ascertain utility industry opinions about the National Photovoltaic Program as it relates to central station applications.

  7. Effects of lactation upon circulating plasma metabolites in cafeteria-fed rats

    OpenAIRE

    Salvadó, J.; Segués Piqué, Teresa; Alemany, Marià; Arola i Ferrer, Lluís

    1986-01-01

    1. The effects of "cafeteria feeding" on primiparous Wistar rats during lactation have been studied by measuring circulating levels of glucose, amino acids, lactate, urea and ammonia as well as glycogen levels in liver and muscle. 2. No significant changes in glucose levels were observed despite alterations in blood glucose compartmentation. 3. Compared with controls, the dams given the cafeteria diet had higher liver glycogen stores which were more easily mobilized at the peak of lactation. ...

  8. Palatable cafeteria diet ameliorates anxiety and depression-like symptoms following an adverse early environment.

    Science.gov (United States)

    Maniam, Jayanthi; Morris, Margaret J

    2010-06-01

    Early trauma contributes to psychosocial disorders later in life. An adverse early environment induced by maternal separation (MS) is known to alter behavioural and stress responses in rats. Palatable food dampens stress responses. We investigated the influence of palatable cafeteria high-fat diet (HFD) on behavioural responses following MS or non-handling (NH), versus 15min brief separation. After littering, Sprague-Dawley rats were exposed to short separation, S15 (15min), prolonged separation, S180 (180min) daily from postnatal days 2 to 14 or were non-handled. Pups were assigned to HFD or chow at weaning. We assessed depression and anxiety-like behaviour with sucrose preference test (SPT) and elevated plus maze (EPM) respectively, and measured hypothalamic CRH and hippocampal glucocorticoid receptor (GR) expression. S180 rats showed increased anxiety-and depression-like behaviours, with increased plasma corticosterone, hypothalamic CRH, and reduced hippocampal GR expression versus S15 rats. Similar effects were observed across gender. These were normalized by provision of HFD, with greater beneficial effects in males. S15 showed no benefit of HFD. NH female rats had less adverse impacts; HFD had beneficial impact on behaviour in NH males. Thus behavioural deficits and gene expression changes induced by early life stress were ameliorated by HFD. These results highlight the important place of palatable food in reducing central stress responses supporting the therapeutic value of 'comfort food'.

  9. Determinação de elementos minerais e traços por ativação neutrônica, em refeições servidas no restaurante da Faculdade de Saúde Pública/USP Determination of mineral and trace elements by neutron activation analysis, in meals served at the central cafeteria of Faculty of Public Health/USP

    Directory of Open Access Journals (Sweden)

    Déborah I.T. FÁVARO

    2000-08-01

    estes elementos nos dias estudados.The objective of this research was to check the nutritional adequacy of diets served to University students related to essential elements and also to monitor for some toxic elements. Within this framework, the aim was to determine the levels of these elements in meals served at the Cafeteria of the School of Public Health at USP used by students and workers along one week. The 5 meals served along the week at the Cafeteria were analyzed separately. Three trays per meal were used to collect the food according to a duplicate portion technique. The centesimal composition of the meals was determined according to the methods suggested by AOAC. Neutron Activation Analysis was used and the concentration of the following elements was determined: Ba, Br, Ca, Ce, Cl, Co, Cr, Cs, Fe, K, Mg, Mn, Mo, Na, Rb, Sb, Sc, Se and Zn. The calculated intake obtained in the present work was compared to the daily recommended values set by RDA, WHO and Reference Man. Regarding macronutrients, the protein and lipid levels were high in some cases. The fiber content of the meals was adequate. Concerning the mineral contents of Br, Ca, Fe, Mg, Mn, Rb, Se and Zn, the intake was adequate, but for the elements K, Mo, Na, Cl and Cr, the intake was too high concerning to recommendations. For the elements Ba, Co, Cs and Sb the daily intakes were compared to the values set by Reference Man. There are no recommendations for Ce and Sc elements. A great variability was also observed in the concentrations of these elements during the period of this study.

  10. Environmental applications of ion chromatography in Eastern and Central Europe.

    Science.gov (United States)

    Michalski, Rajmund

    2010-08-01

    Environmental analytics is one of the most important applications of ion chromatography. It includes determination of ions in water and wastewater as well as in gaseous and solid ones. Nowadays, ion chromatography has almost completely displaced the classical methods of ion determination in these areas. In spite of the fact that the ion chromatography has been officially present in the scientific world for 36 years, its role and popularity is highly diversified in various countries and regions of the world. In highly industrialized countries, it has been a reference method of water and wastewater analysis for years. In other parts of the world, it is not used and appreciated sufficiently despite its undeniable advantages. The following paper is a short overview of the most highly cited scientific and research institutions that conduct research in terms of environmental applications of ion chromatography in Eastern and Central Europe. Furthermore, the paper presents a list of a number of scientific papers referring to the discussed area, published in the years 1996-2009 in some of the most highly cited international scientific journals, and concerning publications of scientists from Eastern and Central Europe seen against the background of Europe and the world.

  11. Dietary education for university students : Effect of putting the poster related to diet or nutrition in the sign stand on university cafeteria dining tables

    OpenAIRE

    冨永, 美穂子; 濱端, 倫子

    2015-01-01

    We investigated the effectiveness of a university cafeteria as a place of dietary education by putting 10 kinds of poster related to diet or nutrition in the sign stand on the dining tables at a university cafeteria over a period of 10 weeks (1 week for each poster). We conducted a questionnaire survey among students using the cafeteria with respect to such items as requests to the cafeteria, awareness of nutritional balance, frequency of eating breakfast, and utility of the posters i...

  12. Applications of Nanotechnology to the Central Nervous System

    Science.gov (United States)

    Blumling, James P., II

    Nanotechnology and nanomaterials, in general, have become prominent areas of academic research. The ability to engineer at the nano scale is critical to the advancement of the physical and medical sciences. In the realm of physical sciences, the applications are clear: smaller circuitry, more powerful computers, higher resolution intruments. However, the potential impact in the fields of biology and medicine are perhaps even grander. The implementation of novel nanodevices is of paramount importance to the advancement of drug delivery, molecular detection, and cellular manipulation. The work presented in this thesis focuses on the development of nanotechnology for applications in neuroscience. The nervous system provides unique challenges and opportunities for nanoscale research. This thesis discusses some background in nanotechnological applications to the central nervous system and details: (1) The development of a novel calcium nanosenser for use in neurons and astrocytes. We implemented the calcium responsive component of Dr. Roger Tsien's Cameleon sensor, a calmodulin-M13 fusion, in the first quantum dot-based calcium sensor. (2) The exploration of cell-penetrating peptides as a delivery mechanism for nanoparticles to cells of the nervous system. We investigated the application of polyarginine sequences to rat primary cortical astrocytes in order to assess their efficacy in a terminally differentiated neural cell line. (3) The development of a cheap, biocompatible alternative to quantum dots for nanosensor and imaging applications. We utilized a positively charged co-matrix to promote the encapsulation of free sulforhodamine B in silica nanoparticles, a departure from conventional reactive dye coupling to silica matrices. While other methods have been invoked to trap dye not directly coupled to silica, they rely on positively charged dyes that typically have a low quantum yield and are not extensively tested biologically, or they implement reactive dyes bound

  13. Engineering Biomaterial Properties for Central Nervous System Applications

    Science.gov (United States)

    Rivet, Christopher John

    Biomaterials offer unique properties that are intrinsic to the chemistry of the material itself or occur as a result of the fabrication process; iron oxide nanoparticles are superparamagnetic, which enables controlled heating in the presence of an alternating magnetic field, and a hydrogel and electrospun fiber hybrid material provides minimally invasive placement of a fibrous, artificial extracellular matrix for tissue regeneration. Utilization of these unique properties towards central nervous system disease and dysfunction requires a thorough definition of the properties in concert with full biological assessment. This enables development of material-specific features to elicit unique cellular responses. Iron oxide nanoparticles are first investigated for material-dependent, cortical neuron cytotoxicity in vitro and subsequently evaluated for alternating magnetic field stimulation induced hyperthermia, emulating the clinical application for enhanced chemotherapy efficacy in glioblastoma treatment. A hydrogel and electrospun fiber hybrid material is first applied to a rat brain to evaluate biomaterial interface astrocyte accumulation as a function of hybrid material composition. The hybrid material is then utilized towards increasing functional engraftment of dopaminergic progenitor neural stem cells in a mouse model of Parkinson's disease. Taken together, these two scenarios display the role of material property characterization in development of biomaterial strategies for central nervous system repair and regeneration.

  14. Obesity induced by cafeteria diet disrupts fertility in the rat by affecting multiple ovarian targets.

    Science.gov (United States)

    Bazzano, M V; Torelli, C; Pustovrh, M C; Paz, D A; Elia, E M

    2015-11-01

    Obesity constitutes a health problem of increasing worldwide prevalence. Among the health detriments caused by obesity, reproduction is disrupted. However, the mechanisms involved in this disruption are not fully understood. Animals fed a cafeteria diet constitute the model for the study of obesity that most closely reflects Western diet habits. The aims of this study were to evaluate whether a cafeteria diet affects ovarian function and to contribute to the understanding of the mechanisms involved. For that purpose, 22-day-old female Wistar rats were fed ad libitum with a standard diet (control group; n = 20) or cafeteria diet (CAF group; n = 20). The cafeteria diet induced obesity and hyperglycaemia, without altering serum triglycerides, cholesterol or C-reactive protein concentrations. This diet also altered ovarian function: the rats showed prolonged dioestrous phases, decreased serum oestradiol concentrations and increased number of antral atretic follicles. Moreover, follicular cysts were detected in the CAF group, concomitantly with a decrease in the number of anti-Müllerian hormone immunoreactive pre-antral follicles and COX-2-positive antral and pre-ovulatory follicles. The authors conclude that a cafeteria diet reduces ovarian reserve, induces the presence of follicular cysts and disturbs the ovulatory process, leading to the delayed pregnancy observed in these animals.

  15. A field assessment of floor slipperiness in a student cafeteria.

    Science.gov (United States)

    Yu, Ruifeng; Li, Kai Way

    2013-01-01

    Investigation of floor slipperiness is critical in studying the risk of slips and falls. This research conducted friction measurements and employee survey on floor slipperiness in a student cafeteria in a university in China in order to study the correlation between the two types of floor slipperiness measure. It was found that the fryer area in kitchen 1 and the meat defrost sink in kitchen 2 had significantly the lowest coefficient of friction (COF) values among all areas in the same kitchen. The results showed that the levels of friction on the floors in different areas in each kitchen were significantly different. Employee perceptions of floor slipperiness among areas were also significantly different. The level of friction and employee perception of floor slipperiness was highly correlated (ρ = 0.87). This implies a good agreement between the two measures. A linear regression model was established to describe the relationship between the perceived floor slipperiness and the measured COF. The model was significant at p < 0.0001 with an R (2) of 0.59.

  16. Availability of drinking water in US public school cafeterias.

    Science.gov (United States)

    Hood, Nancy E; Turner, Lindsey; Colabianchi, Natalie; Chaloupka, Frank J; Johnston, Lloyd D

    2014-09-01

    This study examined the availability of free drinking water during lunchtime in US public schools, as required by federal legislation beginning in the 2011-2012 school year. Data were collected by mail-back surveys in nationally representative samples of US public elementary, middle, and high schools from 2009-2010 to 2011-2012. Overall, 86.4%, 87.4%, and 89.4% of students attended elementary, middle, and high schools, respectively, that met the drinking water requirement. Most students attended schools with existing cafeteria drinking fountains and about one fourth attended schools with water dispensers. In middle and high schools, respondents were asked to indicate whether drinking fountains were clean, and whether they were aware of any water-quality problems at the school. The vast majority of middle and high school students (92.6% and 90.4%, respectively) attended schools where the respondent perceived drinking fountains to be clean or very clean. Approximately one in four middle and high school students attended a school where the survey respondent indicated that there were water-quality issues affecting drinking fountains. Although most schools have implemented the requirement to provide free drinking water at lunchtime, additional work is needed to promote implementation at all schools. School nutrition staff at the district and school levels can play an important role in ensuring that schools implement the drinking water requirement, as well as promote education and behavior-change strategies to increase student consumption of water at school.

  17. 26 CFR 1.125-3 - Effect of the Family and Medical Leave Act (FMLA) on the operation of cafeteria plans.

    Science.gov (United States)

    2010-04-01

    ...) on the operation of cafeteria plans. 1.125-3 Section 1.125-3 Internal Revenue INTERNAL REVENUE... operation of cafeteria plans. The following questions and answers provide guidance on the effect of the Family and Medical Leave Act (FMLA), 29 U.S.C. 2601 et seq., on the operation of cafeteria plans:...

  18. Market research for a business plan : a child-friendly cafeteria

    OpenAIRE

    Rundberg, Janika

    2013-01-01

    The object of this Bachelor's thesis is to see whether there is a market in Turku for a new business plan, a child-friendly cafeteria. The author has an option of starting up a company if the thesis proves that there is a market for the business. The author wanted to know if other people with children feel the same way than she does about the existing cafeteria culture, the lack of healthy food and drink options and not very child-friendly enviroments being the main problems in the market. ...

  19. Cafeteria diet impairs expression of sensory-specific satiety and stimulus-outcome learning

    Directory of Open Access Journals (Sweden)

    Amy Claire Reichelt

    2014-08-01

    Full Text Available A range of animal and human data demonstrates that excessive consumption of palatable food leads to neuroadaptive responses in brain circuits underlying reward. Unrestrained consumption of palatable food has been shown to increase the reinforcing value of food and weaken inhibitory control; however whether it impacts upon the sensory representations of palatable solutions has not been formally tested. These experiments sought to determine whether exposure to a cafeteria diet consisting of palatable high fat foods impacts upon the ability of rats to learn about food-associated cues and the sensory properties of ingested foods. We found that rats fed a cafeteria diet for 2 weeks were impaired in the control of Pavlovian responding in accordance to the incentive value of palatable outcomes associated with auditory cues following devaluation by sensory-specific satiety. Sensory-specific satiety is one mechanism by which a diet containing different foods increases ingestion relative to one lacking variety. Hence, choosing to consume greater quantities of a range of foods may contribute to the current prevalence of obesity. We observed that rats fed a cafeteria diet for 2 weeks showed impaired sensory-specific satiety following consumption of a high calorie solution. The deficit in expression of sensory-specific satiety was also present 1 week following the withdrawal of cafeteria foods. Thus, exposure to obesogenic diets may impact upon neurocircuitry involved in motivated control of behaviour.

  20. Strengthening environmental and educational nutrition programmes in worksite cafeterias and supermarkets in The Netherlands.

    Science.gov (United States)

    Steenhuis, I H; Van Assema, P; Glanz, K

    2001-03-01

    The purpose of this study was to assess conditions for the adoption and continued implementation of different healthy nutrition programmes in worksite cafeterias and supermarkets, i.e. an educational programme and two environmental programmes (a food labelling programme and a food supply programme). Twenty semi-structured interviews were conducted with representatives of worksite cafeterias and supermarkets. Concepts of theories of diffusion were used as a framework for the study. Questions were formulated about the attributes of the innovation, and organizational and personal characteristics that might influence programme adoption and implementation. Results indicated that educational and environmental programmes in both worksite cafeterias and supermarkets should meet specific requirements regarding programme design, methods and materials in order to be adopted and implemented. Besides, some important implementation strategies of the educational and environmental programmes were identified. It is concluded that it seems feasible to conduct educational and environmental intervention programmes in worksite cafeterias and supermarkets, but that certain conditions for adoption and continued implementation have to be met. Based on the implications of this study, the development of an educational programme, a labelling programme and a food supply programme was completed.

  1. Reducing Disruptive Behavior in an Urban School Cafeteria: An Extension of the Good Behavior Game

    Science.gov (United States)

    McCurdy, Barry L.; Lannie, Amanda L.; Barnabas, Ernesto

    2009-01-01

    Non-classroom settings are often the most violence-prone areas within a school. This study investigated the impact of an interdependent group contingency on the disruptive behaviors of students in grades K-6 in an urban school cafeteria. Nine female noontime aides and National School and Community Corps staff members implemented the Lunchroom…

  2. The impact of educational and environmental interventions in Dutch worksite cafeterias

    NARCIS (Netherlands)

    I.H.M. Steenhuis; P. van Assema (Patricia); G.J.P. van Breukelen (Gerard); K. Glanz; G.J. Kok (Gerjo); H. de Vries (Hein)

    2004-01-01

    textabstractEnvironmental interventions as labeling of healthy foods and an increased availability of healthy foods may help consumers to meet the guidelines for a healthy diet. This article describes a study into the effectiveness of two environmental programs to be used in worksite cafeterias alon

  3. Effect of Food Service Nutrition Improvements on Elementary School Cafeteria Lunch Purchase Patterns

    Science.gov (United States)

    Cluss, Patricia A.; Fee, LuAnn; Culyba, Rebecca J.; Bhat, Kiran B.; Owen, Kay

    2014-01-01

    Background: Schools can play a major role in prevention and intervention for childhood obesity. We describe changes in elementary school cafeteria lunch sales patterns resulting from nutritional improvements in menu offerings that were part of a community-wide focus on health. Methods: Elementary school lunch sales data were collected for 1 week…

  4. Consumer Support for Policies to Reduce the Sodium Content in School Cafeterias

    Science.gov (United States)

    Patel, Sheena M.; Gunn, Janelle P.; Merlo, Caitlin L.; Tong, Xin; Cogswell, Mary E.

    2014-01-01

    Purpose/Objectives: The objective of this study was to assess consumer support for policies lowering the sodium content of cafeteria foods in schools. Methods: Data were used from 9,634 adults aged >18 years who responded to questions about sodium in general and in school foods in a 2010 national mail panel survey. Prevalence of consumer…

  5. A Group Contingency Program to Improve the Behavior of Elementary School Students in a Cafeteria

    Science.gov (United States)

    Fabiano, Gregory A.; Pelham, William E., Jr.; Karmazin, Karen; Kreher, Joanne; Panahon, Carlos J.; Carlson, Carl

    2008-01-01

    Studies of behavior modification interventions for disruptive behavior in schools have generally focused on classroom behavior with less research directed toward child behavior in other school settings (e.g., cafeterias). The present report documents the effect of a group contingency intervention with a random reward component, targeting…

  6. Schools′ cafeteria status: Does it affect snack patterns? a qualitative study

    Directory of Open Access Journals (Sweden)

    Fatemeh Esfarjani

    2013-01-01

    Full Text Available Background: The aim of this study was to evaluate patterns of students′ snacks habits regarding to their schools′ cafeteria status in Tehran by focus group discussion (FGD technique. Methods: Participants were 240 students (12-15 years old, selected from12 middle-schools in Tehran. The field study consisted of 24 FGDs sessions; involving 8-10 participants. Collected data were coded, categorized and analyzed using constant comparative method. Results: Over half of the students believed that snack consumption is necessary. Although, majority of students believed that their schools′ cafeterias are not acceptable, they noted them as one of the necessary parts of school. Nearly half of the children were complaining of unvaried and expensive food items. The most purchased items were: Cookies, sandwiches with mayonnaise and ketchup, soft drinks and chocolate milk. Most of the students were interested in having roles in their cafeterias. Conclusions: Schools′ cafeteria are significant sources of supplying adolescents′ snacks, so developing hygienic stores containing healthy and nutritious food items is a key element to affect their snack selection positively. Reaching this goal requires a multi disciplinary approach through participation of students, school staff, parents, and the support of community and media.

  7. Management of Sodium-reduced Meals at Worksite Cafeterias: Perceptions, Practices, Barriers, and Needs among Food Service Personnel

    OpenAIRE

    Lee, Jounghee; Park, Sohyun

    2015-01-01

    Objectives The sodium content of meals provided at worksite cafeterias is greater than the sodium content of restaurant meals and home meals. The objective of this study was to assess the relationships between sodium-reduction practices, barriers, and perceptions among food service personnel. Methods We implemented a cross-sectional study by collecting data on perceptions, practices, barriers, and needs regarding sodium-reduced meals at 17 worksite cafeterias in South Korea. We implemented Ch...

  8. The Application of Centralized Text Editing and Electronic Mail Systems in Libraries: The CMU Experience.

    Science.gov (United States)

    Michalak, Thomas J.

    1984-01-01

    Describes Carnegie-Mellon University Libraries' utilization of three software packages resident on the University's central computers: text editing, text formatting, and electronic mail. Advantages of utilizing central computing resources, introduction of and training in computing systems within libraries, specific applications, and advantages and…

  9. 77 FR 41975 - Southern Star Central Gas Pipeline, Inc.; Notice of Application

    Science.gov (United States)

    2012-07-17

    ... From the Federal Register Online via the Government Publishing Office DEPARTMENT OF ENERGY Federal Energy Regulatory Commission Southern Star Central Gas Pipeline, Inc.; Notice of Application Take notice that on June 27, 2012, Southern Star Central Gas Pipeline, Inc. (Southern Star), 4700 Highway 56, Owensboro, Kentucky 42301, filed...

  10. How the CATCH eat smart program helps implement the USDA regulations in school cafeterias.

    Science.gov (United States)

    Hoelscher, Deanna M; Mitchell, Paul; Dwyer, Johanna; Elder, John; Clesi, Ann; Snyder, Patricia

    2003-08-01

    This article describes the implementation of the U.S. Department of Agriculture's National School Lunch Program (NSLP) standards in school lunch menus in 56 intervention and 20 control schools from the Child and Adolescent Trial for Cardiovascular Health (CATCH) 5 years after the main trial, compared with 12 schools previously unexposed to CATCH. School food service personnel completed questionnaires to assess CATCH guideline implementation, demographic data, behavioral constructs, training, program material use, and participation in competing programs. Five days of menus and recipes were collected from school cafeteria staff, averaged, and compared to USDA School Meal Initiative (SMI) standards. Significant differences between intervention and unexposed schools were found for training and knowledge of CATCH and in mean percentage energy from fat and carbohydrates. Intervention schools most closely met USDA SMI recommendations for fat. Thus, the CATCH Eat Smart Program assisted school cafeterias in meeting USDA guidelines 5 years postimplementation.

  11. Menu Analysis for Improved Customer Demand and Profitability in Hospital Cafeterias.

    Science.gov (United States)

    Mann, Linda L.; MacInnis, Donna; Gardiner, Nicole

    1999-01-01

    Several sophisticated menu analysis methods have been compared in studies using theoretical restaurant menus. Institutional and especially hospital cafeterias differ from commercial restaurants in ways that may influence the effectiveness of these menu analysis methods. In this study, we compared three different menu analysis methods - menu engineering, goal value analysis, and marginal analysis in an institutional setting, to evaluate their relative effectiveness for menu management decision-making. The three methods were used to analyze menu cost and sales data for a representative cafeteria in a large metropolitan hospital. The results were compared with informal analyses by the manager and an employee to determine accuracy and value of information for decision-making. Results suggested that all three methods would improve menu planning and pricing, which in turn would enhance customer demand (revenue) and profitability. However, menu engineering was ranked the easiest of the three methods to interpret.

  12. Effect of Coleus forskohlii extract on cafeteria diet-induced obesity in rats

    OpenAIRE

    Hebbani Nagarajappa Shivaprasad; Sushma Gopalakrishna; Bhanumathy Mariyanna; Midhun Thekkoot; Roopa Reddy; Boreddy Shivanandappa Tippeswamy

    2014-01-01

    Background: Obesity is a metabolic disorder that can lead to adverse metabolic effects on blood pressure, cholesterol, triglycerides and insulin resistance and also increases the risk of coronary heart disease, ischemic stroke and type 2 diabetes mellitus. This study was designed to determine the effect of Coleus forskohlii on obesity and associated metabolic changes in rats fed with cafeteria diet. Objective: The aim of this study was to evaluate antiobesogenic and metabolic benefits of C. f...

  13. Promoting consumption of fruit in elementary school cafeterias. The effects of slicing apples and oranges.

    Science.gov (United States)

    Swanson, Mark; Branscum, Adam; Nakayima, Peace Julie

    2009-10-01

    We examined how slicing apples and oranges affected elementary students' selection and consumption of fruit. Slicing increased the percentage of children selecting and consuming oranges, while a similar effect was not found for apples. The impact of slicing fruit was greatest among younger students. These findings suggest that school cafeterias can increase accessibility and consumption of foods through simple, inexpensive food preparation techniques, with the impact of such measures varying by foods and student characteristics.

  14. Chocolate milk consequences: a pilot study evaluating the consequences of banning chocolate milk in school cafeterias.

    Directory of Open Access Journals (Sweden)

    Andrew S Hanks

    Full Text Available OBJECTIVES: Currently, 68.3% of the milk available in schools is flavored, with chocolate being the most popular (61.6% of all milk. If chocolate milk is removed from a school cafeteria, what will happen to overall milk selection and consumption? METHODS: In a before-after study in 11 Oregon elementary schools, flavored milk-which will be referred to as chocolate milk-was banned from the cafeteria. Milk sales, school enrollment, and data for daily participation in the National School Lunch Program (NSLP were compared year to date. RESULTS: Total daily milk sales declined by 9.9% (p<0.01. Although white milk increased by 161.2 cartons per day (p<0.001, 29.4% of this milk was thrown away. Eliminating chocolate milk was also associated with 6.8% fewer students eating school lunches, and although other factors were also involved, this is consistent with the notion of psychological reactance. CONCLUSIONS: Removing chocolate milk from school cafeterias may reduce calorie and sugar consumption, but it may also lead students to take less milk overall, drink less (waste more of the white milk they do take, and no longer purchase school lunch. Food service managers need to carefully weigh the costs and benefits of eliminating chocolate milk and should consider alternative options that make white milk more convenient, attractive, and normal to choose.

  15. Chocolate Milk Consequences: A Pilot Study Evaluating the Consequences of Banning Chocolate Milk in School Cafeterias

    Science.gov (United States)

    Hanks, Andrew S.; Just, David R.; Wansink, Brian

    2014-01-01

    Objectives Currently, 68.3% of the milk available in schools is flavored, with chocolate being the most popular (61.6% of all milk). If chocolate milk is removed from a school cafeteria, what will happen to overall milk selection and consumption? Methods In a before-after study in 11 Oregon elementary schools, flavored milk–which will be referred to as chocolate milk–was banned from the cafeteria. Milk sales, school enrollment, and data for daily participation in the National School Lunch Program (NSLP) were compared year to date. Results Total daily milk sales declined by 9.9% (p<0.01). Although white milk increased by 161.2 cartons per day (p<0.001), 29.4% of this milk was thrown away. Eliminating chocolate milk was also associated with 6.8% fewer students eating school lunches, and although other factors were also involved, this is consistent with the notion of psychological reactance. Conclusions Removing chocolate milk from school cafeterias may reduce calorie and sugar consumption, but it may also lead students to take less milk overall, drink less (waste more) of the white milk they do take, and no longer purchase school lunch. Food service managers need to carefully weigh the costs and benefits of eliminating chocolate milk and should consider alternative options that make white milk more convenient, attractive, and normal to choose. PMID:24740451

  16. [Peripheral vertigo versus central vertigo. Application of the HINTS protocol].

    Science.gov (United States)

    Batuecas-Caletrío, Ángel; Yáñez-González, Raquel; Sánchez-Blanco, Carmen; González-Sánchez, Enrique; Benito, José; Gómez, José Carlos; Santa Cruz-Ruiz, Santiago

    2014-10-16

    Introduccion. Uno de los dilemas mas importantes concernientes al vertigo en urgencias es su diagnostico diferencial. Existen signos de alarma de gran sensibilidad en la exploracion que pueden ponernos en la pista de encontrarnos ante un vertigo central. Objetivo. Determinar la eficacia de la aplicacion del protocolo HINTS en el diagnostico del accidente cerebrovascular que simula un vertigo periferico. Pacientes y metodos. Estudio observacional descriptivo sobre pacientes ingresados con diagnostico de sindrome vestibular agudo en urgencias. Todos los pacientes fueron objeto de un seguimiento diario hasta la mejoria de sus sintomas con informacion del nistagmo, la maniobra de impulso oculocefalico y el test de skew. Se comparan los resultados del estudio de resonancia magnetica con la alteracion en alguno de esos tres signos a lo largo del ingreso del enfermo. Resultados. Se reunio a 91 pacientes, con una edad media de 55,8 años. Se objetivo un accidente cerebrovascular en ocho de ellos. De estos (edad media: 71 años), en siete existia una alteracion en alguno de los signos HINTS y en uno el estudio fue normal (sensibilidad: 0,88; especificidad: 0,96). Todos ellos tenian algun factor de riesgo vascular. Conclusiones. Una exploracion adecuada y dirigida ante un paciente que acude a urgencias con un sindrome vestibular agudo resulta de vital importancia para establecer el diagnostico diferencial entre la patologia periferica y la central, ya que algunos accidentes cerebrovasculares se pueden presentar bajo la apariencia de un vertigo agudo. Aplicar un protocolo como HINTS permite sospechar la patologia central con una gran sensibilidad y especificidad.

  17. Central Nervous System Multiparameter Optimization Desirability: Application in Drug Discovery.

    Science.gov (United States)

    Wager, Travis T; Hou, Xinjun; Verhoest, Patrick R; Villalobos, Anabella

    2016-06-15

    Significant progress has been made in prospectively designing molecules using the central nervous system multiparameter optimization (CNS MPO) desirability tool, as evidenced by the analysis reported herein of a second wave of drug candidates that originated after the development and implementation of this tool. This simple-to-use design algorithm has expanded design space for CNS candidates and has further demonstrated the advantages of utilizing a flexible, multiparameter approach in drug discovery rather than individual parameters and hard cutoffs of physicochemical properties. The CNS MPO tool has helped to increase the percentage of compounds nominated for clinical development that exhibit alignment of ADME attributes, cross the blood-brain barrier, and reside in lower-risk safety space (low ClogP and high TPSA). The use of this tool has played a role in reducing the number of compounds submitted to exploratory toxicity studies and increasing the survival of our drug candidates through regulatory toxicology into First in Human studies. Overall, the CNS MPO algorithm has helped to improve the prioritization of design ideas and the quality of the compounds nominated for clinical development.

  18. You Don't Have To Dread Cafeteria Duty: A Guide to Surviving Lunchroom, Recess, Bus, and "Other Duties as Assigned."

    Science.gov (United States)

    Novak, Dori E.; Strohmer, Joanne C.

    This book offers educators ideas, plans, games, and reproducibles for making the school cafeteria into an inviting place where students can learn and have fun. Chapter 1, "The Dreaded School Cafeteria Scene," discusses observing the big picture and getting others involved. Chapter 2, "What Could Be," helps create a vision of what could be. Chapter…

  19. CentiServer: A Comprehensive Resource, Web-Based Application and R Package for Centrality Analysis.

    Directory of Open Access Journals (Sweden)

    Mahdi Jalili

    Full Text Available Various disciplines are trying to solve one of the most noteworthy queries and broadly used concepts in biology, essentiality. Centrality is a primary index and a promising method for identifying essential nodes, particularly in biological networks. The newly created CentiServer is a comprehensive online resource that provides over 110 definitions of different centrality indices, their computational methods, and algorithms in the form of an encyclopedia. In addition, CentiServer allows users to calculate 55 centralities with the help of an interactive web-based application tool and provides a numerical result as a comma separated value (csv file format or a mapped graphical format as a graph modeling language (GML file. The standalone version of this application has been developed in the form of an R package. The web-based application (CentiServer and R package (centiserve are freely available at http://www.centiserver.org/.

  20. Altered feeding patterns in rats exposed to a palatable cafeteria diet: increased snacking and its implications for development of obesity.

    Directory of Open Access Journals (Sweden)

    Sarah I Martire

    Full Text Available BACKGROUND: Rats prefer energy-rich foods over chow and eat them to excess. The pattern of eating elicited by this diet is unknown. We used the behavioral satiety sequence to classify an eating bout as a meal or snack and compared the eating patterns of rats fed an energy rich cafeteria diet or chow. METHODS: Eight week old male Sprague Dawley rats were exposed to lab chow or an energy-rich cafeteria diet (plus chow for 16 weeks. After 5, 10 and 15 weeks, home-cage overnight feeding behavior was recorded. Eating followed by grooming then resting or sleeping was classified as a meal; whereas eating not followed by the full sequence was classified as a snack. Numbers of meals and snacks, their duration, and waiting times between feeding bouts were compared between the two conditions. RESULTS: Cafeteria-fed rats ate more protein, fat and carbohydrate, consistently ingesting double the energy of chow-fed rats, and were significantly heavier by week 4. Cafeteria-fed rats tended to take multiple snacks between meals and ate fewer meals than chow-fed rats. They also ate more snacks at 5 weeks, were less effective at compensating for snacking by reducing meals, and the number of snacks in the majority of the cafeteria-fed rats was positively related to terminal body weights. CONCLUSIONS: Exposure to a palatable diet had long-term effects on feeding patterns. Rats became overweight because they initially ate more frequently and ultimately ate more of foods with higher energy density. The early increased snacking in young cafeteria-fed rats may represent the establishment of eating habits that promote weight gain.

  1. Cafeteria diet inhibits insulin clearance by reduced insulin-degrading enzyme expression and mRNA splicing.

    Science.gov (United States)

    Brandimarti, P; Costa-Júnior, J M; Ferreira, S M; Protzek, A O; Santos, G J; Carneiro, E M; Boschero, A C; Rezende, L F

    2013-11-01

    Insulin clearance plays a major role in glucose homeostasis and insulin sensitivity in physiological and/or pathological conditions, such as obesity-induced type 2 diabetes as well as diet-induced obesity. The aim of the present work was to evaluate cafeteria diet-induced obesity-induced changes in insulin clearance and to explain the mechanisms underlying these possible changes. Female Swiss mice were fed either a standard chow diet (CTL) or a cafeteria diet (CAF) for 8 weeks, after which we performed glucose tolerance tests, insulin tolerance tests, insulin dynamics, and insulin clearance tests. We then isolated pancreatic islets for ex vivo glucose-stimulated insulin secretion as well as liver, gastrocnemius, visceral adipose tissue, and hypothalamus for subsequent protein analysis by western blot and determination of mRNA levels by real-time RT-PCR. The cafeteria diet induced insulin resistance, glucose intolerance, and increased insulin secretion and total insulin content. More importantly, mice that were fed a cafeteria diet demonstrated reduced insulin clearance and decay rate as well as reduced insulin-degrading enzyme (IDE) protein and mRNA levels in liver and skeletal muscle compared with the control animals. Furthermore, the cafeteria diet reduced IDE expression and alternative splicing in the liver and skeletal muscle of mice. In conclusion, a cafeteria diet impairs glucose homeostasis by reducing insulin sensitivity, but it also reduces insulin clearance by reducing IDE expression and alternative splicing in mouse liver; however, whether this mechanism contributes to the glucose intolerance or helps to ameliorate it remains unclear.

  2. The impact of educational and environmental interventions in Dutch worksite cafeterias.

    Science.gov (United States)

    Steenhuis, Ingrid; Van Assema, Patricia; Van Breukelen, Gerard; Glanz, Karen; Kok, Gerjo; De Vries, Hein

    2004-09-01

    Environmental interventions such as labeling and an increased availability of healthy foods may help consumers to meet guidelines for a healthy diet. This article describes a study into the effectiveness of two environmental programs to be used in worksite cafeterias along with an educational program. The aim of the interventions was to reduce fat intake, and to increase fruit and vegetable intake. In the labeling program, low-fat products were labeled. The food supply program comprised an increased availability of low-fat products and fruits and vegetables in worksite cafeterias. The educational program consisted of information about healthy nutrition through brochures, table tents, a self-help manual and posters. The design consisted of a pre-test-post-test experimental control group design, with four conditions: the educational program; the food supply program plus educational program; the labeling program plus educational program; and a control group. Seventeen worksites were randomly assigned to one of the four research conditions. Total fat, fruit and vegetable intake was measured with a quantitative, self-administered food frequency questionnaire (35 questions). Intake during lunch was measured by asking respondents to write down which food items they had purchased during their last lunch in the cafeteria. Furthermore, sales data for some targeted product categories were collected (milk, butter, cheese, meat products, desserts). For the whole study population, no significant effects on consumption data were found for any of the programs. The data showed a beneficial and significant treatment effect of the labeling program on total fat intake for respondents who believed they ate a high-fat diet. Sales data revealed a significant effect of the labeling program on desserts, but not for the other products.

  3. Podnikatelský plán. Cafeteria a bistro

    OpenAIRE

    Křepelková, Romana

    2014-01-01

    Křepelková, R. The Business plan -- the establishment of a cafeteria and bistro. Bachelor thesis. Prague: University of Economics in Prague, 2015. The aim of the bachelor thesis is to create a business plan that will serve as a basis for making decision if the plan is viable and if has the potential to succeed. The work has two parts - theoretical and practical. The theoretical part provides all information concerning the business plan and its creation. The practical part of the thesis contai...

  4. Smoking ban in all restaurants and cafeterias on the CERN site

    CERN Multimedia

    CSR

    2006-01-01

    In 2005 the SCC decided that there would be a total smoking ban in all restaurants and satellite cafeterias on the CERN site, except for the designated area in Restaurant No.1. Unfortunately, it seems that this ban is often over-looked, resulting in an unhealthy and unpleasant environment for the users and staff of these facilities. You are asked to respect this ban and are reminded that smoking is only permitted in the room in Restaurant 1 specially installed for this purpose. The CSR Restaurant Monitoring Committee

  5. Recycled Water Reuse Permit Renewal Application for the Central Facilities Area Sewage Treatment Plant

    Energy Technology Data Exchange (ETDEWEB)

    Lewis, Mike [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2014-09-01

    This renewal application for a Recycled Water Reuse Permit is being submitted in accordance with the Idaho Administrative Procedures Act 58.01.17 “Recycled Water Rules” and the Municipal Wastewater Reuse Permit LA-000141-03 for continuing the operation of the Central Facilities Area Sewage Treatment Plant located at the Idaho National Laboratory. The permit expires March 16, 2015. The permit requires a renewal application to be submitted six months prior to the expiration date of the existing permit. For the Central Facilities Area Sewage Treatment Plant, the renewal application must be submitted by September 16, 2014. The information in this application is consistent with the Idaho Department of Environmental Quality’s Guidance for Reclamation and Reuse of Municipal and Industrial Wastewater and discussions with Idaho Department of Environmental Quality personnel.

  6. Multi-Centrality Graph Spectral Decompositions and Their Application to Cyber Intrusion Detection

    Energy Technology Data Exchange (ETDEWEB)

    Chen, Pin-Yu; Choudhury, Sutanay; Hero, Alfred

    2016-03-01

    Many modern datasets can be represented as graphs and hence spectral decompositions such as graph principal component analysis (PCA) can be useful. Distinct from previous graph decomposition approaches based on subspace projection of a single topological feature, e.g., the centered graph adjacency matrix (graph Laplacian), we propose spectral decomposition approaches to graph PCA and graph dictionary learning that integrate multiple features, including graph walk statistics, centrality measures and graph distances to reference nodes. In this paper we propose a new PCA method for single graph analysis, called multi-centrality graph PCA (MC-GPCA), and a new dictionary learning method for ensembles of graphs, called multi-centrality graph dictionary learning (MC-GDL), both based on spectral decomposition of multi-centrality matrices. As an application to cyber intrusion detection, MC-GPCA can be an effective indicator of anomalous connectivity pattern and MC-GDL can provide discriminative basis for attack classification.

  7. Dietary supplementation with a specific melon concentrate reverses vascular dysfunction induced by cafeteria diet

    Science.gov (United States)

    Carillon, Julie; Jover, Bernard; Cristol, Jean-Paul; Rouanet, Jean-Max; Richard, Sylvain; Virsolvy, Anne

    2016-01-01

    Background Obesity-related metabolic syndrome is associated with high incidence of cardiovascular diseases partially consecutive to vascular dysfunction. Therapeutic strategies consisting of multidisciplinary interventions include nutritional approaches. Benefits of supplementation with a specific melon concentrate, enriched in superoxide dismutase (SOD), have previously been shown on the development of insulin resistance and inflammation in a nutritional hamster model of obesity. Objective We further investigated arterial function in this animal model of metabolic syndrome and studied the effect of melon concentrate supplementation on arterial contractile activity. Design and results The study was performed on a hamster model of diet-induced obesity. After a 15-week period of cafeteria diet, animals were supplemented during 4 weeks with a specific melon concentrate (Cucumis melo L.) Contractile responses of isolated aorta to various agonists and antagonists were studied ex vivo. Cafeteria diet induced vascular contractile dysfunction associated with morphological remodeling. Melon concentrate supplementation partially corrected these dysfunctions; reduced morphological alterations; and improved contractile function, especially by increasing nitric oxide bioavailability and expression of endogenous SOD. Conclusions Supplementation with the specific melon concentrate improves vascular dysfunction associated with obesity. This beneficial effect may be accounted for by induction of endogenous antioxidant defense. Such an approach in line with nutritional interventions could be a useful strategy to manage metabolic syndrome–induced cardiovascular trouble. PMID:27834185

  8. Dietary supplementation with a specific melon concentrate reverses vascular dysfunction induced by cafeteria diet

    Directory of Open Access Journals (Sweden)

    Julie Carillon

    2016-11-01

    Full Text Available Background: Obesity-related metabolic syndrome is associated with high incidence of cardiovascular diseases partially consecutive to vascular dysfunction. Therapeutic strategies consisting of multidisciplinary interventions include nutritional approaches. Benefits of supplementation with a specific melon concentrate, enriched in superoxide dismutase (SOD, have previously been shown on the development of insulin resistance and inflammation in a nutritional hamster model of obesity. Objective: We further investigated arterial function in this animal model of metabolic syndrome and studied the effect of melon concentrate supplementation on arterial contractile activity. Design and results: The study was performed on a hamster model of diet-induced obesity. After a 15-week period of cafeteria diet, animals were supplemented during 4 weeks with a specific melon concentrate (Cucumis melo L. Contractile responses of isolated aorta to various agonists and antagonists were studied ex vivo. Cafeteria diet induced vascular contractile dysfunction associated with morphological remodeling. Melon concentrate supplementation partially corrected these dysfunctions; reduced morphological alterations; and improved contractile function, especially by increasing nitric oxide bioavailability and expression of endogenous SOD. Conclusions: Supplementation with the specific melon concentrate improves vascular dysfunction associated with obesity. This beneficial effect may be accounted for by induction of endogenous antioxidant defense. Such an approach in line with nutritional interventions could be a useful strategy to manage metabolic syndrome–induced cardiovascular trouble.

  9. Design of an ARM-based Automatic Rice-Selling Machine for Cafeterias

    Directory of Open Access Journals (Sweden)

    Zhiliang Kang

    2016-02-01

    Full Text Available To address the problems of low selling efficiency, poor sanitation conditions, labor-intensive requirement, and quick rice cooling speed in manual rice selling in cafeterias, especially in colleges and secondary schools, this paper presented an Advanced RISC Machines (ARM microprocessor-based rice-selling machine for cafeterias. The machines consisted of a funnel-shaped rice bin, a thermal insulation box, and a conveying and scattering mechanism. Moreover, this machine exerts fuzzy control over stepper motor rpm, and the motor drives the conveyor belt with a scraper to scatter rice, deliver it, and keep it warm. Apart from an external 4*4 keyboard, a point of sale (POS machine, an ARM process and a pressure sensor, the machine is also equipped with card swiping and weighting mechanisms to achieve functions of card swiping payment and precise measurement, respectively. In addition, detection of the right amount of rice and the alarm function are achieved using an ultrasonic sensor and a beeper, respectively. The presence of the rice container on the rice outlet is detected by an optoelectronic switch. Results show that this rice-selling machine achieves precise measurement, quick card swiping, fast rice selling, stable operation, and good rice heat preservation. Therefore, the mechanical design enables the machine to achieve its goals.

  10. [Hygienic quality of meat used in institutional food services: university cafeterias in Ouagadougou (Burkina Faso)].

    Science.gov (United States)

    Ilboudo, A J; Savadogo, A; Barro, N; Ouedraogo, M; Traore, A S

    2009-01-01

    This present study was conducted to assess the hygienic quality of meals served in three cafeterias at the national university in Ouagadougou and the compliance of kitchen staff with good hygiene practices. Microbiological analyses assessed the hygienic quality of the raw meat and of meat-based meals. The results showed poor hygiene practices by food handlers along the food chain. These observations were confirmed by the identification of salmonella, coliform and staphylococcal bacteria in raw meat and cooked meals. Overall, 60% of the raw meat samples were unsatisfactory for aerobic mesophilic flora and 6.6% for salmonella. For the cooked meat meals, on the other hand, 45% of the samples were satisfactory for aerobic mesophilic flora, 100% for salmonella, 93.3% for fecal thermotolerant coliforms and 96.6% for staphylococci. These results showed poor hygiene in the handling of raw meat, but a clear improvement in hygienic quality after cooking. Raising the awareness of cafeteria staff about compliance with hygiene rules appears primordial. Moreover improvement of the food environment, the kitchen equipment, and organization as well as the introduction of a cleaning-disinfection programme would make it possible to provide more hygienic meals in these institutional facilities.

  11. Food safety objectives for Listeria monocytogenes in Spanish food sampled in cafeterias and restaurants.

    Science.gov (United States)

    Doménech, E; Amorós, J A; Escriche, I

    2011-09-01

    To gain more insight into the context of food safety management by public administrations, food safety objectives must be studied. The Valencian administration quantified the prevalence of Listeria monocytogenes in cafeterias and restaurants in this region of Spain between 2002 and 2010. The results obtained from this survey are presented here for 2,262 samples of fish, salad, egg, cold meat, and mayonnaise dishes. Microbiological criteria defined for L. monocytogenes were used to differentiate acceptable and unacceptable samples; more than 99.9% of the samples were acceptable. These findings indicate that established food safety objectives are achievable, consumer health at the time of consumption can be safeguarded, and food safety management systems such as hazard analysis critical control point plans or good manufacturing practices implemented in food establishments are effective. Monitoring of foods and food safety is an important task that must continue to reduce the current L. monocytogenes prevalence of 0.1% in restaurant or cafeteria dishes, which could adversely affect consumer health.

  12. Effect of Argyreia speciosa root extract on cafeteria diet-induced obesity in rats

    Directory of Open Access Journals (Sweden)

    Shiv Kumar

    2011-01-01

    Full Text Available Objectives : To evaluate the antiobesity effects of the ethanolic extract of Argyreia speciosa roots in rats fed with a cafeteria diet (CD. Materials and Methods : Obesity was induced in albino rats by feeding them a CD daily for 42 days, in addition to a normal diet. Body weight and food intake was measured initially and then every week thereafter. On day 42, the serum biochemical parameters were estimated and the animals were sacrificed with an overdose of ether. The, liver and parametrial adipose tissues were removed and weighed immediately. The liver triglyceride content was estimated. The influence of the extract on the pancreatic lipase activity was also determined by measuring the rate of release of oleic acid from triolein. Results : The body weight at two-to-six weeks and the final parametrial adipose tissue weights were significantly lowered (P < 0.01 and P < 0.05, respectively in rats fed with the CD with Argyreia speciosa extract 500 mg/kg/day as compared to the CD alone. The extract also significantly reduced (P < 0.01 the serum contents of leptin, total cholesterol, low density lipoprotein (LDL, and triglycerides, which were elevated in rats fed with CD alone. In addition, the extract inhibited the induction of fatty liver with the accumulation of hepatic triglycerides. The extract also showed inhibition of pancreatic lipase activity by using triolein as a substrate. Conclusions : The ethanolic extract of Argyreia speciosa roots produces inhibitory effects on cafeteria diet-induced obesity in rats.

  13. The Relationship between Nutrition Knowledge and School Cafeteria Purchases of Seventh Grade Students in a Rural Indiana School District

    Science.gov (United States)

    Pucciarelli, Deanna; McNeany, Terry; Friesen, Carol

    2013-01-01

    Purpose/Objective: School cafeterias have the potential to positively contribute to the prevention and treatment of childhood obesity. The purpose of this project was to assess adolescents' nutrition knowledge and dietary choices, and to measure the relationship between students' nutrition knowledge and the type of food items purchased in their…

  14. Go Slow Whoa Meal Patterns: Cafeteria Staff and Teacher Perceptions of Effectiveness in "Winning with Wellness" Schools

    Science.gov (United States)

    Slawson, Deborah L.; Southerland, Jodi; Lowe, Elizabeth F.; Dalton, William T.; Pfortmiller, Deborah T.; Schetzina, Karen

    2013-01-01

    Background: School-based interventions hold promise for child obesity prevention. Implemented as a part of the "Winning with Wellness" obesity prevention project, the "Go Slow Whoa" meal pattern (GSW) was designed to promote healthier foods in school cafeterias. This investigation determined perceived program effectiveness and…

  15. A nutrition labeling intervention in worksite cafeterias: an implementation evaluation across two large catering companies in the Netherlands.

    Science.gov (United States)

    Vyth, Ellis L; Van Der Meer, Esther W C; Seidell, Jacob C; Steenhuis, Ingrid H M

    2012-06-01

    By both increasing the availability of healthy foods and labeling these products with the Choices logo, caterers may facilitate employees to make a healthier choice in their worksite cafeterias. The aim of this study was to explore which attributes influence the implementation of the Choices logo in worksite cafeterias in the Netherlands. Questionnaires were completed by catering managers of 316 cafeterias of two large caterers in the Netherlands (response rate 49.8%). Attributes from the Diffusion of Innovations Theory were used to investigate whether they could predict implementation. Compatibility (consistency with the beliefs of the catering manager; OR = 1.52), voluntariness (perception of the implementation as voluntary; OR = 0.50), result demonstrability (ability to communicate the implementation; OR = 1.52) and complexity in the sense of time (time needed for implementation; OR = 0.70) were the best predictors for the frequency of offering fresh Choices products (all significant). For the frequency of using Choices promotion material, voluntariness (OR = 0.54), result demonstrability (OR = 1.51) and relative advantage (perceived advantage of the implementation; OR = 1.44) were the best predictors (all significant). In conclusion, this study provides unique insights into which perceived attributes influence the implementation of a nutrition logo in worksite cafeterias. To increase the implementation, the Choices logo should be consistent with catering managers' ideas about healthy food, the workload of implementing the logo should be limited and it could be recommended to incorporate the logo in the health policy of the caterer.

  16. Influence of placement of a nutrition logo on cafeteria menu items on lunchtime food Choices at Dutch work sites.

    Science.gov (United States)

    Vyth, Ellis L; Steenhuis, Ingrid H M; Heymans, Martijn W; Roodenburg, Annet J C; Brug, Johannes; Seidell, Jacob C

    2011-01-01

    This study investigated the effectiveness of labeling foods with the Choices nutrition logo on influencing cafeteria menu selection and the behavioral determinants of menu choices in work site cafeterias in the Netherlands. A cluster randomized controlled trial was conducted. Intervention cafeterias (n=13), where the Choices logo was used to promote healthier eating for a 3-week period, were compared with control cafeterias (n=12), which offered the same menu without the logo. Sales data were collected daily for 9 weeks, from March to May 2009. In addition, employees from one intervention and one control company completed an online questionnaire at baseline and after the intervention (n=368) in which the behavioral determinants of food choice (ie, attitude, self-efficacy, and intention) and logo use were measured. Generalized estimating equation analyses, χ² tests, t tests and linear regression analyses were performed. No nutritionally meaningful intervention effects were found in the sales of sandwiches, soups, snacks, fruit, and salads. Also, no significant differences in behavioral determinants were found. "Intention to eat healthier" and "paying attention to product information" were positively associated with self-reported consumption of foods with the Choices logo at lunch. The intervention did not have a significant effect on employees' lunchtime food choices. Labeling healthy choices might be useful for health-conscious employees in the volitional phase of behavior change. Further research should focus on the possible health benefits of menu reformulation in the catering sector.

  17. Project Refresh: Testing the Efficacy of a School-Based Classroom and Cafeteria Intervention in Elementary School Children

    Science.gov (United States)

    Song, Hee-Jung; Grutzmacher, Stephanie; Munger, Ash L.

    2016-01-01

    Background: The purpose of this study was to assess the effect of a school-based nutrition program using a cafeteria environment intervention and classroom nutrition education on self-reported fruit and vegetable (FV) consumption, self-efficacy to select FV, and preference for healthy foods. Methods: Using quasi-experimental pre-post design with 3…

  18. A Pricing Strategy To Promote Sales of Lower Fat Foods in High School Cafeterias: Acceptability and Sensitivity Analysis.

    Science.gov (United States)

    Hannan, Peter; French, Simone A.; Story, Mary; Fulkerson, Jayne A.

    2002-01-01

    Examined the purchase patterns of seven targeted foods under conditions in which prices of three high-fat foods were raised and prices of four low-fat foods were lowered in a high school cafeteria over 1 school year. Data collected on food sales and revenues supported the feasibility of a pricing strategy that offered low-fat foods at lower prices…

  19. INTERGEO - Central/East European Collaboration Network on direct application of geothermal energy

    Energy Technology Data Exchange (ETDEWEB)

    Popovski, K. [Central/East European Collaboration Network on Direct Application of Geothermal Energy, Bitola (Yugoslavia); Arpasi, M. [International Geothermal Association - European Branch, Budapest (Hungary)

    1997-12-01

    A proposal for organisation of a Network to be known as INTERGEO is presented, which should extend and reinforce the cooperation for the development of the direct application of geothermal energy between the developed EC countries and the ones of the so called Central/East European region. Unter the term `developed countries` for this particular energy source utilisation mainly Italy, France and Germany should be understood. The Central/East European region consists the following countries: Albania, Bosnia and Herzegovina, Bulgaria, Belarus, Croatia, Czech Republic, Estonia, Hungary, Latvia, Lituania, Macedonia, Moldova, Poland, Roumania, Slovenia, Slovakia, Turkey, Ukraine and Yugoslavia. The idea itself, the need and possibilities for organisation, possible plan of action and expected benefits for the EC and Central/East European countries are elaborated in order to come to the conclusions for the proposal justifiableness and feasibility for realisation. (orig.)

  20. [Multimedia application in mobile platform for teaching the measurement of central venous pressure].

    Science.gov (United States)

    Galvão, Elizabeth Correia Ferreira; Püschel, Vilanice Alves Araújo

    2012-10-01

    This study aimed to develop and assess an application software for the teaching of the procedure Manual Measurement of the Central Venous Pressure which can be used in mobile devices. The research was conducted in three phases (Survey of needs; Methodology for multimedia application development and evaluation of the multimedia application).The multimedia was the method chosen because it favors an encouraging and dynamic environment, as it integrates images and texts into an application software available for cell phones, constituting a mobile and autonomous means for learning. The research allowed to demonstrate the feasibility of the development from this pedagogical tool and open up prospects for believing that, in Nursing education, the technology available can uncover new ways of learning in a meaningful manner.

  1. Process evaluation of two environmental nutrition programmes and an educational nutrition programme conducted at supermarkets and worksite cafeterias in the Netherlands

    NARCIS (Netherlands)

    I.H.M. Steenhuis; P. van Assema (Patricia); A. Reubsaet; G.J. Kok (Gerjo)

    2004-01-01

    textabstractThis article describes the process evaluation of two environmental programs and a educational nutrition program, implemented at supermarkets and worksite cafeterias. Studies conducted earlier, indicated that the programs had no effect on consumers’ eating behavior. Consequently, the more

  2. Small Prizes Improve Food Selection in a School Cafeteria Without Increasing Waste.

    Science.gov (United States)

    Hudgens, Michelle E; Barnes, Allison S; Lockhart, Mary Kate; Ellsworth, Samantha C; Beckford, Monna; Siegel, Robert M

    2017-02-01

    We recently demonstrated that small prizes given for a "Power Plate" (plain fat-free milk, entrée, fruit and vegetable) can be used in an elementary school cafeteria to increase healthful food selection by over 300%. The purpose of this study was to measure changes in food waste when the Power Plate (PP) program is implemented. The PP intervention was conducted at an inner-city elementary school. Emoticons were placed next to the preferred foods and children were given a small prize if they selected the PP. Data were obtained by observation and cash register receipts. The trays of 111 students before the intervention and 96 after were examined for content and waste. PP selection increased from 2% to 73% ( P < .001). There was no significant change in waste. We conclude that small prizes as an incentive for better food selection does not lead to an increase food waste.

  3. An intervention study targeting energy and nutrient intake in worksite cafeterias.

    Science.gov (United States)

    Lowe, Michael R; Tappe, Karyn A; Butryn, Meghan L; Annunziato, Rachel A; Coletta, Maria C; Ochner, Christopher N; Rolls, Barbara J

    2010-08-01

    Modifying the food environment is a promising strategy for promoting healthier eating behavior. This study aimed to evaluate nutritional and weight changes in a program that used worksite cafeterias to reduce employees' calorie content of purchased foods and improve their macronutrient intake. Participants were randomly assigned to one of two conditions: 1) only environmental change (i.e., the introduction of 10 new low-energy-density (ED) foods and provision of labels for all foods sold at lunch, which listed ED, calories, and macronutrient content) or 2) the environmental change plus pricing incentives for purchasing low-ED foods and education about low-ED eating delivered in four, 1-hour group sessions. Participant lunch choices were monitored electronically at the point of purchase for 3 months before the intervention was instituted (i.e., the baseline period) and for 3 months afterward (i.e., intervention period). Participants were adults (n=96, BMI=29.7+/-6.0 kg/m(2)) who regularly ate lunch at their workplace cafeteria. There was no difference between groups in total energy intake over the study period. Across groups, energy and percent of energy from fat decreased and percent of energy from carbohydrate increased from baseline to the intervention period (all p<.01). Follow-up analyses, conducted by averaging Baseline Months 1 and 2 and comparing them to Intervention Month 3 as a conservative estimate of overall impact of the intervention, indicated that change in energy, carbohydrate, and fat intake remained significant (p<.001). Providing nutrition labels and reducing the ED of selected foods was associated with improved dietary intake.

  4. [Frequency of use of school cafeterias in middle and high schools in 3 French districts].

    Science.gov (United States)

    Michaud, C; Feur, E; Gerbouin-Rérolle, P; Leynaud-Rouaud, C; Chateil, S; Gourdon, M

    2000-09-01

    Reports from the French Ministry of Education warn of a decrease in the use of school food services, especially in sensitive urban areas. They also suggest that this decline has led to cases of malnutrition. This article describes the characteristics of the current supply of school meals and measures the evolution of demand observed between 1992 and 1996 in relation to the economic situation of students' families. The study was carried out in 3 departments in France: Doubs, Herault, and Val de Marne. The administrators of all public and private middle and high schools in the 3 departments received a questionnaire asking them to describe the services offered in their cafeterias and to provide the corresponding statistical and accounting data. External food services near the schools were also taken into account. Seventy-nine percent of schools responded to the survey. Concerning the services offered, 91% of schools have their own cafeterias, of which 81% are managed by the schools. Concerning the evolution of utilisation, a significant decrease in the number of meals served in seen in middle schools. On the other hand, high schools have observed stable utilisation. The positive changes in utilisation are linked, in middle schools, to characteristics of the schools' internal food services (self-service, choice of main courses, modulation of seats). In high schools, positive changes in the utilisation of school services are linked to the lack of external food services near the schools. As middle schools and high schools control the logistics and management of food services offered to students, they are potentially in a position to influence a policy on this issue. The evolution in utilisation is very different among departments and between middle and high schools. While economic precariousness has a negative structural effect on utilisation, it doesn't seem to be a major factor in the evolution of the decrease observed over the past few years.

  5. Hypolipidemic and weight reducing activity of the ethanolic extract of Tamarindus indica fruit pulp in cafeteria diet- and sulpiride-induced obese rats

    Directory of Open Access Journals (Sweden)

    Vaneeta Jindal

    2011-01-01

    Full Text Available Objectives: To investigate the effect of ethanolic extract of fruit pulp of Tamarindus indica Linn. (Family: Caesalpiniaceae on obesity in rats using cafeteria diet-induced obesity and antipsychotic drug (sulpiride-induced obesity. Materials and Methods: Cafeteria diet was administered for 40 successive days to male Wistar rats and sulpiride (20 mg/kg, i.p. was administered for 28 successive days to female Wistar rats. In separate groups of animals, the ethanolic extract (50 and 100 mg/kg p.o. of Tamarindus indica fruit was administered along with cafeteria diet for 40 successive days to Wistar male rats and along with sulpiride for 28 successive days to Wistar female rats. Results: Cafeteria diet alone significantly increased body weight, serum total cholesterol, triglycerides, and glucose levels and decreased HDL cholesterol in male rats as compared to control. Sulpiride per se significantly increased the levels of glucose, triglycerides, cholesterol and there was no significant effect on HDL-cholesterol in female rats as compared to control. Ethanolic extract showed a significant decrease in body weight, serum cholesterol, and triglycerides and a significant increase in HDL-cholesterol in cafeteria diet- and sulpiride-induced obese rats as compared to their respective control groups. Conclusions: Thus, the ethanolic extract of Tamarindus indica fruit pulp showed a significant weight-reducing and hypolipidemic activity in cafeteria diet- and sulpiride-induced obese rats.

  6. Effects of the cafeteria diet on the salivary glands of trained and sedentary Wistar rats=Efeitos da dieta de cafeteria sobre as glândulas salivares de ratos Wistar sedentários e treinados

    Directory of Open Access Journals (Sweden)

    Sonia Lucy Molinari

    2012-01-01

    Full Text Available The objective of this work was to study the effect of the aerobic physical training and the cafeteria diet introduced after weaning of Wistar rats and on the morphology of the main salivary glands (parotid, submandibular, sublingual. Male rats after weaning were subjected to the cafeteria diet or the standard rodent chow, and either performed aerobic physical training in a treadmill for 100 days, or did not performed any physical activity. Analyses were done considering the response in body weight, adipose tissues and salivary glands, and the data were submitted to statistical treatment (p O objetivo deste trabalho foi avaliar as características morfológicas das glândulas salivares (parótida, submandibular, sublingual apresentadas por ratos submetidos a treinamento físico aeróbio e dieta de cafeteria após o período de lactação. Ratos machos após a lactação consumiram dieta de cafeteria ou ração-padrão para roedores e realizaram treinamento físico aeróbio em esteira rolante por um período de 100 dias, ou não realizaram nenhuma atividade física. Foram feitas análises sobre a resposta do peso corporal, dos tecidos adiposos e das glândulas salivares e os dados submetidos a tratamento estatístico (p < 0,05. A análise morfológica e morfométrica das glândulas salivares foi realizada a partir de cortes histológicos corados com Hematoxilina e Eosina. Apesar do comportamento normofágico, os roedores alimentados com dieta de cafeteria apresentaram maior quantidade de gordura corporal, com repercussão sobre o peso da glândula parótida. A análise morfométrica das glândulas submandibulares indicou redução na proporção dos ácinos serosos como efeito da dieta de cafeteria e do treinamento físico. No entanto, excesso de gordura corporal, dieta de cafeteria e/ou treinamento físico não influenciou a organização histológica das glândulas salivares. Concluiu-se que as glândulas parótidas e submandibulares são mais

  7. Planning and development of the Better Bites program: a pricing manipulation strategy to improve healthy eating in a hospital cafeteria.

    Science.gov (United States)

    Liebert, Mina L; Patsch, Amy J; Smith, Jennifer Howard; Behrens, Timothy K; Charles, Tami; Bailey, Taryn R

    2013-07-01

    The Better Bites program, a hospital cafeteria nutrition intervention strategy, was developed by combining evidence-based practices with hospital-specific formative research, including key informant interviews, the Nutrition Environment Measures Study in Restaurants, hospital employee surveys, and nutrition services staff surveys. The primary program components are pricing manipulation and marketing to promote delicious, affordable, and healthy foods to hospital employees and other cafeteria patrons. The pricing manipulation component includes decreasing the price of the healthy items and increasing the price of the unhealthy items using a 35% price differential. Point-of-purchase marketing highlights taste, cost, and health benefits of the healthy items. The program aims to increase purchases of healthy foods and decrease purchases of unhealthy foods, while maintaining revenue neutrality. This article addresses the formative research, planning, and development that informed the Better Bites program.

  8. Understanding the Functional Central Limit Theorems with Some Applications to Unit Root Testing with Structural Change

    Directory of Open Access Journals (Sweden)

    Juan Carlos Aquino

    2013-06-01

    Full Text Available The application of different unit root statistics is by now a standard practice in empirical work. Even when it is a practical issue, these statistics have complex nonstandard distributions depending on functionals of certain stochastic processes, and their derivations represent a barrier even for many theoretical econometricians. These derivations are based on rigorous and fundamental statistical tools which are not (very well known by standard econometricians. This paper aims to fill this gap by explaining in a simple way one of these fundamental tools: namely, the Functional Central Limit Theorem. To this end, this paper analyzes the foundations and applicability of two versions of the Functional Central Limit Theorem within the framework of a unit root with a structural break. Initial attention is focused on the probabilistic structure of the time series to be considered. Thereafter, attention is focused on the asymptotic theory for nonstationary time series proposed by Phillips (1987a, which is applied by Perron (1989 to study the effects of an (assumed exogenous structural break on the power of the augmented Dickey-Fuller test and by Zivot and Andrews (1992 to criticize the exogeneity assumption and propose a method for estimating an endogenous breakpoint. A systematic method for dealing with efficiency issues is introduced by Perron and Rodriguez (2003, which extends the Generalized Least Squares detrending approach due to Elliot et al. (1996. An empirical application is provided.

  9. Effect of point-of-purchase calorie labeling on restaurant and cafeteria food choices: A review of the literature

    Directory of Open Access Journals (Sweden)

    French Simone A

    2008-10-01

    Full Text Available Abstract Background Eating away from home has increased in prevalence among US adults and now comprises about 50% of food expenditures. Calorie labeling on chain restaurant menus is one specific policy that has been proposed to help consumers make better food choices at restaurants. The present review evaluates the available empirical literature on the effects of calorie information on food choices in restaurant and cafeteria settings. Methods Computer-assisted searches were conducted using the PUBMED database and the Google Scholar world wide web search engine to identify studies published in peer-review journals that evaluated calorie labeling of cafeteria or restaurant menu items. Studies that evaluated labeling only some menu items (e.g. low calorie foods only were excluded from the review since the influence of selective labeling may be different from that which may be expected from comprehensive labeling. Results Six studies were identified that met the selection criteria for this review. Results from five of these studies provide some evidence consistent with the hypothesis that calorie information may influence food choices in a cafeteria or restaurant setting. However, results from most of these studies suggest the effect may be weak or inconsistent. One study found no evidence of an effect of calorie labeling on food choices. Each of the studies had at least one major methodological shortcoming, pointing toward the need for better designed studies to more rigorously evaluate the influence of point-of-purchase calorie labeling on food choices. Conclusion More research is needed that meets minimum standards of methodological quality. Studies need to include behavioral outcomes such as food purchase and eating behaviors. Also, studies need to be implemented in realistic settings such as restaurants and cafeterias.

  10. A pricing strategy to promote sales of lower fat foods in high school cafeterias: acceptability and sensitivity analysis.

    Science.gov (United States)

    Hannan, Peter; French, Simone A; Story, Mary; Fulkerson, Jayne A

    2002-01-01

    Prices of four low fat foods were reduced about 25% and prices of three high fat foods were increased about 10% to determine the impact on food purchases in a Midwestern suburban high school cafeteria to explore the impact of price on purchases. Low fat foods averaged about 13% of total sales. Sensitivity analysis was used to estimate that low fat foods would probably have averaged about 9% of total sales without the reduced price.

  11. Treadmill intervention attenuates the cafeteria diet-induced impairment of stress-coping strategies in young adult female rats

    OpenAIRE

    Cigarroa, Igor; Ferrer Lalanza, Jaume; Caimari, Antoni; Bas, Josep M. del; Capdevila Ortís, Lluís; Arola i Ferrer, Lluís; Escorihuela, Rosa Maria

    2016-01-01

    The current prevalence of diet-induced overweight and obesity in adolescents and adults is continuously growing. Although the detrimental biochemical and metabolic consequences of obesity are widely studied, its impact on stress-coping behavior and its interaction with specific exercise doses (in terms of intensity, duration and frequency) need further investigation. To this aim, we fed adolescent rats either an obesogenic diet (cafeteria diet, CAF) or standard chow (ST). Each group was subdi...

  12. Workers intake too much salt from dishes of eating out and food service cafeterias; direct chemical analysis of sodium content.

    Science.gov (United States)

    Park, Hae-Ryun; Jeong, Gye-Ok; Lee, Seung-Lim; Kim, Jin-Young; Kang, Soon-Ah; Park, Kun-Young; Ryou, Hyun-Joo

    2009-01-01

    The average sodium intake of Koreans was reported to be 5,279.9 mg/day, which is one of the highest intake levels worldwide. The average Koreans intake 19.6% of sodium from kimchi, showing kimchi as the main contributor of sodium in this country (Ministry of Health and Welfare, 2005). The sodium content of dishes that are frequently chosen by workers, and which were served by foodservice cafeterias were chemically analyzed. The average sodium content of one meal provided by 10 foodservice cafeterias was 2,777.7 mg. Twenty-one, one-dish-meals, frequently chosen by workers for a lunch menu, were collected at 4 different restaurants for each menu by one male, aged in the twenties and analyzed chemically also. Workers who eat lunch at a workplace cafeteria everyday could intake about 8 g of salt at a one-time meal and those who eat out for a one-dish-meal would intake 3-8 g of salt without counting sodium content from the side dishes. From these study results, one could estimate that over 10 g of salt could be possible for a single meal for workers who eat out everyday. A nationwide nutrition campaign and education for low salt diets for restaurant owners and foodservice providers should be seriously considered.

  13. Evaluation of Soil Flushing for Application to the Deep Vadose Zone in the Hanford Central Plateau

    Energy Technology Data Exchange (ETDEWEB)

    Truex, Michael J.; Oostrom, Martinus; Zhang, Z. F.; Carroll, Kenneth C.; Schramke, Janet A.; Wietsma, Thomas W.; Tartakovsky, Guzel D.; Gordon, Kathryn A.; Last, George V.

    2010-11-01

    Soil flushing was included in the Deep Vadose Zone Treatability Test Plan for the Hanford Central Plateau as a technology with the potential to remove contaminants from the vadose zone. Soil flushing operates through the addition of water, and if necessary an appropriate mobilizing agent, to mobilize contaminants and flush them from the vadose zone and into the groundwater where they are subsequently captured by a pump-and-treat system. There are uncertainties associated with applying soil flushing technology to contaminants in the deep vadose zone at the Hanford Central Plateau. The modeling and laboratory efforts reported herein are intended to provide a quantitative assessment of factors that impact water infiltration and contaminant flushing through the vadose zone and into the underlying groundwater. Once in the groundwater, capture of the contaminants would be necessary, but this aspect of implementing soil flushing was not evaluated in this effort. Soil flushing was evaluated primarily with respect to applications for technetium and uranium contaminants in the deep vadose zone of the Hanford Central Plateau.

  14. Cannabis, Cannabinoids, and Cerebral Metabolism: Potential Applications in Stroke and Disorders of the Central Nervous System.

    Science.gov (United States)

    Latorre, Julius Gene S; Schmidt, Elena B

    2015-09-01

    No compound has generated more attention in both the scientific and recently in the political arena as much as cannabinoids. These diverse groups of compounds referred collectively as cannabinoids have both been vilified due to its dramatic and potentially harmful psychotropic effects and glorified due to its equally dramatic and potential application in a number of acute and chronic neurological conditions. Previously illegal to possess, cannabis, the plant where natural form of cannabinoids are derived, is now accepted in a growing number of states for medicinal purpose, and some even for recreational use, increasing opportunities for more scientific experimentation. The purpose of this review is to summarize the growing body of literature on cannabinoids and to present an overview of our current state of knowledge of the human endocannabinoid system in the hope of defining the future of cannabinoids and its potential applications in disorders of the central nervous system, focusing on stroke.

  15. Effect of cafeteria diet history on cue-, pellet-priming-, and stress-induced reinstatement of food seeking in female rats.

    Directory of Open Access Journals (Sweden)

    Yu-Wei Chen

    Full Text Available BACKGROUND: Relapse to unhealthy eating habits is a major problem in human dietary treatment. The individuals most commonly seeking dietary treatment are overweight or obese women, yet the commonly used rat reinstatement model to study relapse to palatable food seeking during dieting primarily uses normal-weight male rats. To increase the clinical relevance of the relapse to palatable food seeking model, here we pre-expose female rats to a calorically-dense cafeteria diet in the home-cage to make them overweight prior to examining the effect of this diet history on cue-, pellet-priming- and footshock-induced reinstatement of food seeking. METHODS: Post-natal day 32 female Long-Evans rats had seven weeks of home-cage access to either chow only or daily or intermittent cafeteria diet alongside chow. Next, they were trained to self-administer normally preferred 45 mg food pellets accompanied by a tone-light cue. After extinction, all rats were tested for reinstatement induced by discrete cue, pellet-priming, and intermittent footshock under extinction conditions. RESULTS: Access to daily cafeteria diet and to a lesser degree access to intermittent cafeteria diet decreased food pellet self-administration compared to chow-only. Prior history of these cafeteria diets also reduced extinction responding, cue- and pellet-priming-induced reinstatement. In contrast, modest stress-induced reinstatement was only observed in rats with a history of daily cafeteria diet. CONCLUSION: A history of cafeteria diet does not increase the propensity for cue- and pellet-priming-induced relapse in the rat reinstatement model but does appear to make rats more susceptible to footshock stress-induced reinstatement.

  16. Marked increase in rat red blood cell membrane protein glycosylation by one-month treatment with a cafeteria diet.

    Science.gov (United States)

    Oliva, Laia; Baron, Cristian; Fernández-López, José-Antonio; Remesar, Xavier; Alemany, Marià

    2015-01-01

    Background and Objectives. Glucose, an aldose, spontaneously reacts with protein amino acids yielding glycosylated proteins. The compounds may reorganize to produce advanced glycosylation products, which regulatory importance is increasingly being recognized. Protein glycosylation is produced without the direct intervention of enzymes and results in the loss of function. Glycosylated plasma albumin, and glycosylated haemoglobin are currently used as index of mean plasma glucose levels, since higher glucose availability results in higher glycosylation rates. In this study we intended to detect the early changes in blood protein glycosylation elicited by an obesogenic diet. Experimental Design. Since albumin is in constant direct contact with plasma glucose, as are the red blood cell (RBC) membranes, we analyzed their degree or glycosylation in female and male rats, either fed a standard diet or subjected to a hyper-energetic self-selected cafeteria diet for 30 days. This model produces a small increase in basal glycaemia and a significant increase in body fat, leaving the animals in the initial stages of development of metabolic syndrome. We also measured the degree of glycosylation of hemoglobin, and the concentration of glucose in contact with this protein, that within the RBC. Glycosylation was measured by colorimetric estimation of the hydroxymethylfurfural liberated from glycosyl residues by incubation with oxalate. Results. Plasma glucose was higher in cafeteria diet and in male rats, both independent effects. However, there were no significant differences induced by sex or diet in either hemoglobin or plasma proteins. Purified RBC membranes showed a marked effect of diet: higher glycosylation in cafeteria rats, which was more marked in females (not in controls). In any case, the number of glycosyl residues per molecule were higher in hemoglobin than in plasma proteins (after correction for molecular weight). The detected levels of glucose in RBC were lower

  17. Marked increase in rat red blood cell membrane protein glycosylation by one-month treatment with a cafeteria diet

    Directory of Open Access Journals (Sweden)

    Laia Oliva

    2015-07-01

    Full Text Available Background and Objectives. Glucose, an aldose, spontaneously reacts with protein amino acids yielding glycosylated proteins. The compounds may reorganize to produce advanced glycosylation products, which regulatory importance is increasingly being recognized. Protein glycosylation is produced without the direct intervention of enzymes and results in the loss of function. Glycosylated plasma albumin, and glycosylated haemoglobin are currently used as index of mean plasma glucose levels, since higher glucose availability results in higher glycosylation rates. In this study we intended to detect the early changes in blood protein glycosylation elicited by an obesogenic diet.Experimental Design. Since albumin is in constant direct contact with plasma glucose, as are the red blood cell (RBC membranes, we analyzed their degree or glycosylation in female and male rats, either fed a standard diet or subjected to a hyper-energetic self-selected cafeteria diet for 30 days. This model produces a small increase in basal glycaemia and a significant increase in body fat, leaving the animals in the initial stages of development of metabolic syndrome. We also measured the degree of glycosylation of hemoglobin, and the concentration of glucose in contact with this protein, that within the RBC. Glycosylation was measured by colorimetric estimation of the hydroxymethylfurfural liberated from glycosyl residues by incubation with oxalate.Results. Plasma glucose was higher in cafeteria diet and in male rats, both independent effects. However, there were no significant differences induced by sex or diet in either hemoglobin or plasma proteins. Purified RBC membranes showed a marked effect of diet: higher glycosylation in cafeteria rats, which was more marked in females (not in controls. In any case, the number of glycosyl residues per molecule were higher in hemoglobin than in plasma proteins (after correction for molecular weight. The detected levels of glucose in

  18. Elemental concentrations in kidney and liver of mice fed with cafeteria or standard diet determined by particle induced X-ray emission

    Energy Technology Data Exchange (ETDEWEB)

    Dimer Leffa, Daniela [Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806-000 Criciúma, SC (Brazil); Iochims dos Santos, Carla Eliete; Debastiani, Rafaela; Amaral, Livio; Yoneama, Maria Lucia; Ferraz Dias, Johnny [Ion Implantation Laboratory, Physics Institute, Federal University of Rio Grande do Sul, Porto Alegre (Brazil); Moraes Andrade, Vanessa, E-mail: vmoraesdeandrade@yahoo.com.br [Graduate Program in Health Sciences, Health Sciences Unit, University of Southern Santa Catarina, 88806-000 Criciúma, SC (Brazil)

    2014-01-01

    The importance of trace elements in human health is well known and their main source is daily diet. Nowadays, one of the biggest issues is the presence of these micronutrients in levels much higher than required, leading to potential toxic effects. The aim of this work was to investigate the elemental content in organs of mice fed with cafeteria or standard diet using PIXE. Twelve male Swiss mice were divided into two groups: control group (standard chow) and cafeteria group (high-caloric diet). After 17 weeks, samples of different organs (kidney and liver) were collected and prepared for PIXE analysis. The Fe concentration in kidney and liver was statistically higher in animals that received the cafeteria diet (p < 0.001). The Al and Si kidney contents were significantly higher for cafeteria diet in relation to standard diet (p < 0.05). Moreover, the standard diet showed significant differences for Cl and K (p < 0.05) in comparison to cafeteria diet in kidney, and for P, S and Zn (p < 0.005) in liver.

  19. Reliability of the hospital nutrition environment scan for cafeterias, vending machines, and gift shops.

    Science.gov (United States)

    Winston, Courtney P; Sallis, James F; Swartz, Michael D; Hoelscher, Deanna M; Peskin, Melissa F

    2013-08-01

    According to ecological models, the physical environment plays a major role in determining individual health behaviors. As such, researchers have started targeting the consumer nutrition environment of large-scale foodservice operations when implementing obesity-prevention programs. In 2010, the American Hospital Association released a call-to-action encouraging health care facilities to join in this movement and improve their facilities' consumer nutrition environments. The Hospital Nutrition Environment Scan (HNES) for Cafeterias, Vending Machines, and Gift Shops was developed in 2011, and the present study evaluated the inter-rater reliability of this instrument. Two trained raters visited 39 hospitals in southern California and completed the HNES. Percent agreement, kappa statistics, and intraclass correlation coefficients were calculated. Percent agreement between raters ranged from 74.4% to 100% and kappa statistics ranged from 0.458 to 1.0. The intraclass correlation coefficient for the overall nutrition composite scores was 0.961. Given these results, the HNES demonstrated acceptable reliability metrics and can now be disseminated to assess the current state of hospital consumer nutrition environments.

  20. Leptin signal transduction underlies the differential metabolic response of LEW and WKY rats to cafeteria diet.

    Science.gov (United States)

    Martínez-Micaelo, N; González-Abuín, N; Ardévol, A; Pinent, M; Petretto, E; Behmoaras, J; Blay, M

    2016-01-01

    Although the effect of genetic background on obesity-related phenotypes is well established, the main objective of this study is to determine the phenotypic responses to cafeteria diet (CAF) of two genetically distinct inbred rat strains and give insight into the molecular mechanisms that might be underlying. Lewis (LEW) and Wistar-Kyoto (WKY) rats were fed with either a standard or a CAF diet. The effects of the diet and the strain in the body weight gain, food intake, respiratory quotient, biochemical parameters in plasma as well as in the expression of genes that regulate leptin signalling were determined. Whereas CAF diet promoted weight gain in LEW and WKY rats, as consequence of increased energy intake, metabolic management of this energy surplus was significantly affected by genetic background. LEW and WKY showed a different metabolic profile, LEW rats showed hyperglycaemia, hypertriglyceridemia and high FFA levels, ketogenesis, high adiposity index and inflammation, but WKY did not. Leptin signalling, and specifically the LepRb-mediated regulation of STAT3 activation and Socs3 gene expression in the hypothalamus were inversely modulated by the CAF diet in LEW (upregulated) and WKY rats (downregulated). In the present study, we show evidence of gene-environment interactions in obesity exerted by differential phenotypic responses to CAF diet between LEW and WKY rats. Specifically, we found the leptin-signalling pathway as a divergent point between the strain-specific adaptations to diet.

  1. Modeling Land Application of Food-Processing Wastewater in the Central Valley, California

    Science.gov (United States)

    Rubin, Y.; Benito, P.; Miller, G.; McLaughlin, J.; Hou, Z.; Hermanowicz, S.; Mayer, U.

    2007-12-01

    California's Central Valley contains over 640 food-processing plants, serving a multi-billion dollar agricultural industry. These processors consume approximately 7.9 x 107 m3 of water per year. Approximately 80% of these processors discharge the resulting wastewater, which is typically high in organic matter, nitrogen, and salts, to land, and many of these use land application as a treatment method. Initial investigations revealed elevated salinity levels to be the most common form of groundwater degradation near land application sites, followed by concentrations of nitrogen compounds, namely ammonia and nitrate. Enforcement actions have been taken against multiple food processors, and the regulatory boards have begun to re-examine the land disposal permitting process. This paper summarizes a study that was commissioned in support of these actions. The study has multiple components which will be reviewed briefly, including: (1) characterization of the food-processing related waste stream; (2) fate and transport of the effluent waste stream in the unsaturated zone at the land application sites; (3) fate and transport of the effluent waste stream at the regional scale; (4) predictive uncertainty due to spatial variability and data scarcity at the land application sites and at the regional scale; (5) problem mitigation through off-site and in-situ actions; (6) long-term solutions. The emphasis of the talk will be placed on presenting and demonstrating a stochastic framework for modeling the transport and attenuation of these wastes in the vadose zone and in the saturated zone, and the related site characterization needs, as affected by site conditions, water table depth, waste water application rate, and waste constituent concentrations.

  2. An application-layer based centralized information access control for VPN

    Institute of Scientific and Technical Information of China (English)

    OUYANG Kai; ZHOU Jing-li; XIA Tao; YU Sheng-sheng

    2006-01-01

    With the rapid development of Virtual Private Network (VPN), many companies and organizations use VPN to implement their private communication. Traditionally, VPN uses security protocols to protect the confidentiality of data, the message integrity and the endpoint authentication. One core technique of VPN is tunneling, by which clients can access the internal servers traversing VPN. However, the tunneling technique also introduces a concealed security hole. It is possible that ifone vicious user can establish tunneling by the VPN server, he can compromise the internal servers behind the VPN server. So this paper presents a novel Application-layer based Centralized Information Access Control (ACIAC) for VPN to solve this problem.To implement an efficient, flexible and multi-decision access control model, we present two key techniques to ACIAC-the centralized management mechanism and the stream-based access control. Firstly, we implement the information center and the constraints/events center for ACIAC. By the two centers, we can provide an abstract access control mechanism, and the material access control can be decided dynamically by the ACIAC's constraint/event mechanism. Then we logically classify the VPN communication traffic into the access stream and the data stream so that we can tightly couple the features of VPN communication with the access control model. We also provide the design of our ACIAC prototype in this paper.

  3. E-business and its Application in Conditions of Central European Market

    Directory of Open Access Journals (Sweden)

    Naci Tolga Saruc

    2013-07-01

    Full Text Available Aim of this paper is highlighting possibilities in effective utilization of Information and Communication Technologies for supporting entrepreneurship (e-business for Small and Medium enterprises. The core research carried on for duration of twelve months covered analysis and following presentation of possibilities of practical utilization of e-business applications. Furthermore research was oriented towards innovative forms of marketing communication in Real Corporation conducting business in Central European market. Analyzing data on collected findings can add value towards gaining a significant competitive advantage in form of better understanding of real facts influencing entrepreneurship in principle. This can lead consequently to positive influence on corporate effectiveness in the environment of Small and Medium enterprises.

  4. Betweenness centrality and its applications from modeling traffic flows to network community detection

    Science.gov (United States)

    Ren, Yihui

    network and we demonstrate that the changes can propagate globally, affecting traffic several hundreds of miles away. Because of its principled nature, this method can inform many applications related to human mobility driven flows in spatial networks, ranging from transportation, through urban planning to mitigation of the effects of catastrophic events. In the second part of the thesis we focus on network deconstruction and community detection problems, both intensely studied topics in network science, using a weighted betweenness centrality approach. We present an algorithm that solves both problems efficiently and accurately and demonstrate that on both benchmark networks and data networks.

  5. On Improving the Quality of Military College Cafeterias Run by Private Owners%部队高校食堂社会化水平探析

    Institute of Scientific and Technical Information of China (English)

    张长文

    2012-01-01

    This paper suggests some measures to address cafeterias run by private owners in terms of cafeteria cost ment by private owners the problems with the transfer of military cafeterias into the control and some analysis of disa:dvantages of the manage-%高校食堂社会化已实施多年,针对部队高校食堂社会化改革过程中存在的问题,以成本控制为例,分析了影响保障水平的不利因素,提出了提高社会化经营水平的具体对策。

  6. Cafeteria diet-induced insulin resistance is not associated with decreased insulin signaling or AMPK activity and is alleviated by physical training in rats

    DEFF Research Database (Denmark)

    Brandt, Nina; De Bock, Katrien; Richter, Erik

    2010-01-01

    Excess energy intake via a palatable low-fat diet (cafeteria diet) is known to induce obesity and glucose intolerance in rats. However, the molecular mechanisms behind this adaptation are not known, and it is also not known whether exercise training can reverse it. Male Wistar rats were assigned...... to 12-wk intervention groups: chow-fed controls (CON), cafeteria diet (CAF), and cafeteria diet plus swimming exercise during the last 4 wk (CAF(TR)). CAF feeding led to increased body weight (16%, P ... was counteracted by training. In the perfused hindlimb, insulin-stimulated glucose transport in red gastrocnemius muscle was completely abolished in CAF and rescued by exercise training. Apart from a tendency toward an approximately 20% reduction in both basal and insulin-stimulated Akt Ser(473) phosphorylation (P...

  7. Application of pesticide transport model for simulating diazinon runoff in California’s central valley

    Science.gov (United States)

    Joyce, Brian A.; Wallender, Wesley W.; Mailapalli, Damodhara R.

    2010-12-01

    Dormant spray application of pesticides to almond and other stone fruit orchards is the main source of diazinon during the winter in California's central valley. Understanding the pesticide transport and the tradeoffs associated with the various management practices is greatly facilitated by the use of physically-based contaminant transport models. In this study, performance of Joyce's et al. (2008) pesticide transport model was evaluated using experimental data collected from two ground treatments such as resident vegetation and bare soil. The model simulation results obtained in calibration and validation process were analyzed for pesticide concentration and total load. The pesticide transport model accurately predicted the pesticide concentrations and total load in the runoff from bare field and was capable of simulating chemical responses to rainfall-runoff events. In case of resident vegetation, the model results exhibited a larger range of variation than was observed in the bare soil simulations due to increased model parameterization with the addition of foliage and thatch compartments. Furthermore, the model was applied to study the effect of runoff lag time, extent of crop cover, organic content of soil and post-application irrigation on the pesticide peak concentration and total load. Based on the model results, recommendations were suggested to growers prior to implementing certain management decisions to mitigate diazinon transport in the orchard's spray runoff.

  8. Performance of Layers Supplemented with Either Complete Feed or Diets in Cafeteria Feeding System Under Semi-scavenging Condition in a Tropical Environment

    OpenAIRE

    Das, Chamali; Roy, Bimol Chandra; Ranvig, Hans; Riise, Jens Christian; Iwamoto, Hisao; Tabata, Shoji

    2008-01-01

    1. Egg production ability and its economical aspect were compared among the hens kept under semi-scavenging condition on two feeding systems with four supplementary levels. Commercial balanced feed and cafeteria feeding diet were fed the hens at 40 g, 60 g, 80 g and 120 g/day respectively. Cafeteria feeding diet was composed of 70% mixed feed (40% broken rice, 20% rice polish and 10% wheat bran), 27% soybean meal and 3% oyster shell. 2. The mean feed residue was 4-8 g/day in the hens fed 40...

  9. Gamification of dietary decision-making in an elementary-school cafeteria.

    Science.gov (United States)

    Jones, Brooke A; Madden, Gregory J; Wengreen, Heidi J; Aguilar, Sheryl S; Desjardins, E Anne

    2014-01-01

    Despite the known health benefits of doing so, most US children do not consume enough fruits and vegetables (FV). School-based interventions can be effective in increasing FV consumption, but the most effective of these require that schools allocate their time, effort, and financial resources to implementing the program: expenditures that schools may be reluctant to provide in climates of academic accountability and economic austerity. The present demonstration project used a behaviorally based gamification approach to develop an intervention designed to increase FV consumption while minimizing material and labor costs to the school. During the intervention, the school (N = 180 students in grades K-8) played a cooperative game in which school-level goals were met by consuming higher-than-normal amounts of either fruit or vegetables (alternating-treatments experimental design). School-level consumption was quantified using a weight-based waste measure in the cafeteria. Over a period of 13 school days, fruit consumption increased by 66% and vegetable consumption by 44% above baseline levels. Use of an alternating-treatment time-series design with differential levels of FV consumption on days when fruit or vegetable was targeted for improvement supported the role of the intervention in these overall consumption increases. In post-intervention surveys, teachers rated the intervention as practical in the classroom and enjoyed by their students. Parent surveys revealed that children were more willing to try new FV at home and increased their consumption of FV following the intervention. These findings suggest that a behaviorally based gamification approach may prove practically useful in addressing concerns about poor dietary decision-making by children in schools.

  10. Gamification of dietary decision-making in an elementary-school cafeteria.

    Directory of Open Access Journals (Sweden)

    Brooke A Jones

    Full Text Available Despite the known health benefits of doing so, most US children do not consume enough fruits and vegetables (FV. School-based interventions can be effective in increasing FV consumption, but the most effective of these require that schools allocate their time, effort, and financial resources to implementing the program: expenditures that schools may be reluctant to provide in climates of academic accountability and economic austerity. The present demonstration project used a behaviorally based gamification approach to develop an intervention designed to increase FV consumption while minimizing material and labor costs to the school. During the intervention, the school (N = 180 students in grades K-8 played a cooperative game in which school-level goals were met by consuming higher-than-normal amounts of either fruit or vegetables (alternating-treatments experimental design. School-level consumption was quantified using a weight-based waste measure in the cafeteria. Over a period of 13 school days, fruit consumption increased by 66% and vegetable consumption by 44% above baseline levels. Use of an alternating-treatment time-series design with differential levels of FV consumption on days when fruit or vegetable was targeted for improvement supported the role of the intervention in these overall consumption increases. In post-intervention surveys, teachers rated the intervention as practical in the classroom and enjoyed by their students. Parent surveys revealed that children were more willing to try new FV at home and increased their consumption of FV following the intervention. These findings suggest that a behaviorally based gamification approach may prove practically useful in addressing concerns about poor dietary decision-making by children in schools.

  11. Cafeteria diet-induced obesity causes oxidative damage in white adipose.

    Science.gov (United States)

    Johnson, Amy R; Wilkerson, Matthew D; Sampey, Brante P; Troester, Melissa A; Hayes, D Neil; Makowski, Liza

    2016-04-29

    Obesity continues to be one of the most prominent public health dilemmas in the world. The complex interaction among the varied causes of obesity makes it a particularly challenging problem to address. While typical high-fat purified diets successfully induce weight gain in rodents, we have described a more robust model of diet-induced obesity based on feeding rats a diet consisting of highly palatable, energy-dense human junk foods - the "cafeteria" diet (CAF, 45-53% kcal from fat). We previously reported that CAF-fed rats became hyperphagic, gained more weight, and developed more severe hyperinsulinemia, hyperglycemia, and glucose intolerance compared to the lard-based 45% kcal from fat high fat diet-fed group. In addition, the CAF diet-fed group displayed a higher degree of inflammation in adipose and liver, mitochondrial dysfunction, and an increased concentration of lipid-derived, pro-inflammatory mediators. Building upon our previous findings, we aimed to determine mechanisms that underlie physiologic findings in the CAF diet. We investigated the effect of CAF diet-induced obesity on adipose tissue specifically using expression arrays and immunohistochemistry. Genomic evidence indicated the CAF diet induced alterations in the white adipose gene transcriptome, with notable suppression of glutathione-related genes and pathways involved in mitigating oxidative stress. Immunohistochemical analysis indicated a doubling in adipose lipid peroxidation marker 4-HNE levels compared to rats that remained lean on control standard chow diet. Our data indicates that the CAF diet drives an increase in oxidative damage in white adipose tissue that may affect tissue homeostasis. Oxidative stress drives activation of inflammatory kinases that can perturb insulin signaling leading to glucose intolerance and diabetes.

  12. INCA-CE: a Central European initiative in nowcasting severe weather and its applications

    Science.gov (United States)

    Kann, A.; Pistotnik, G.; Bica, B.

    2012-04-01

    The INCA-CE (Integrated Nowcasting through Comprehensive Analysis - Central Europe) project aims at implementing a transnational weather information system as well as applications for different socio-economic sectors to reduce risks of major economic damage and loss of life caused by severe weather. Civil protection and also stakeholders from economic sectors are in a growing need of accurate and reliable short-term weather forecasts. Within INCA-CE, a state-of-the art nowcasting system (INCA) is implemented at weather services throughout the European Union's CE (Central Europe) Programme Area, providing analyses and short term forecasts to the aforementioned end-users. In a coherent approach, the INCA (Integrated Nowcasting through Comprehensive Analysis) system will be adapted for implementation and use in a number of partner countries. Within transregional working groups, the gap between short-term weather information and its downstream activities in hydrological disaster management, civil protection and road management will be bridged and best practice management and measure plans will be produced. A web-based platform for outreach to related socio-economic sectors will initiate and foster a dialogue between weather services and further stakeholders like tourism or the insurance sector, flood authorities for disaster management, and the construction industry for cost-efficient scheduling and planning. Furthermore, the project will produce a compact guideline for policy makers on how to combine structural development aspects with these new features. In the present paper, an outline of the project implementation, a short overview about the INCA system and two case studies on precipitation nowcasts will be given. Moreover, directions for further developments both within the INCA system and the INCA-CE project will be pointed out.

  13. Application of dental nanomaterials: potential toxicity to the central nervous system

    Directory of Open Access Journals (Sweden)

    Feng X

    2015-05-01

    Full Text Available Xiaoli Feng,1 Aijie Chen,1 Yanli Zhang,1 Jianfeng Wang,2 Longquan Shao,1 Limin Wei2 1Nanfang Hospital, Southern Medical University, Guangzhou, 2School and Hospital of Stomatology, Wenzhou Medical University, Wenzhou, People’s Republic of China Abstract: Nanomaterials are defined as materials with one or more external dimensions with a size of 1–100 nm. Such materials possess typical nanostructure-dependent properties (eg, chemical, biological, optical, mechanical, and magnetic, which may differ greatly from the properties of their bulk counterparts. In recent years, nanomaterials have been widely used in the production of dental materials, particularly in light polymerization composite resins and bonding systems, coating materials for dental implants, bioceramics, endodontic sealers, and mouthwashes. However, the dental applications of nanomaterials yield not only a significant improvement in clinical treatments but also growing concerns regarding their biosecurity. The brain is well protected by the blood–brain barrier (BBB, which separates the blood from the cerebral parenchyma. However, in recent years, many studies have found that nanoparticles (NPs, including nanocarriers, can transport through the BBB and locate in the central nervous system (CNS. Because the CNS may be a potential target organ of the nanomaterials, it is essential to determine the neurotoxic effects of NPs. In this review, possible dental nanomaterials and their pathways into the CNS are discussed, as well as related neurotoxicity effects underlying the in vitro and in vivo studies. Finally, we analyze the limitations of the current testing methods on the toxicological effects of nanomaterials. This review contributes to a better understanding of the nano-related risks to the CNS as well as the further development of safety assessment systems. Keywords: dental, nanomaterials, central nervous system, toxicity, testing methods, risk assessment

  14. Correlation between centrality metrics and their application to the opinion model

    NARCIS (Netherlands)

    Li, C.; Li, Q.; Van Mieghem, P.F.A.; Stanley, H.E.; Wang, H.

    2015-01-01

    In recent decades, a number of centrality metrics describing network properties of nodes have been proposed to rank the importance of nodes. In order to understand the correlations between centrality metrics and to approximate a high-complexity centrality metric by a strongly correlated low-complexi

  15. Application of ICT (Information and Communication Technology) in the Management of Universities in the North-Central State of Nigeria

    Science.gov (United States)

    Oboegbulem, Angie Ijeoma; Godwin, Ochai

    2013-01-01

    This study investigated the application of ICT (information and communication technology) in the management of universities in the north-central Nigeria. The study was a descriptive survey. The population of the study comprised 1,294 respondents in federal and state universities (763 in federal and 531 in state universities). The sample size…

  16. Analysis of the Solar Resource Information Datasets for Thermal and/or electric Generation Using a Geographical Information System. Cases of Application: Central Cafeteria - University of the Valley, Cali Municipality and Farm {sup P}ozo Verde{sup ,} Jamundi Municipality , Cauca Valley, Colombia; Analisis de las Fuentes de Informacion sobre Recurso Solar para Generacion Termica y/o Electrica Empleando un Sistema de Informacion Geografica. Casos de Aplicacion: Cafeteria Central - Universidad del Valle, Municipio de Cali y Granja {sup P}ozo Verde{sup ,} Municipio de Jamundi, Valle del Cauca, Colombia

    Energy Technology Data Exchange (ETDEWEB)

    Dominguez, J.; Manrique, P. A.; Pinedo, I.

    2009-10-12

    In this report, two examples of renewable energy assessments based on Geographical Information Systems are presented. Several case studies have been carried out in the Valley of Cauca (Colombia), and one on them has been used to size a hybrid system. The results of this particular case study are presented in a second report. The aim of this document is analysing the different sources of data that could be used in the characterization of solar energy for electricity and electricity-heat use. With this purpose, data of two areas in Valley of Cauca obtained from the Atlas of Solar Radiation of Colombia, SWERA project and SSE-NASA have been compared. The data coming from these sources has been analysed using a Geographical Information System, and the conclusions are described along with cartographic and numeric products. These reports are the result of a collaboration established between Universidad del Valle (Colombia) and CIEMAT (Spain), and have been done by the author while his staying at our center included on his PhD program.

  17. Improved high temperature solar absorbers for use in Concentrating Solar Power central receiver applications.

    Energy Technology Data Exchange (ETDEWEB)

    Stechel, Ellen Beth; Ambrosini, Andrea; Hall, Aaron Christopher; Lambert, Timothy L.; Staiger, Chad Lynn; Bencomo, Marlene

    2010-09-01

    Concentrating solar power (CSP) systems use solar absorbers to convert the heat from sunlight to electric power. Increased operating temperatures are necessary to lower the cost of solar-generated electricity by improving efficiencies and reducing thermal energy storage costs. Durable new materials are needed to cope with operating temperatures >600 C. The current coating technology (Pyromark High Temperature paint) has a solar absorptance in excess of 0.95 but a thermal emittance greater than 0.8, which results in large thermal losses at high temperatures. In addition, because solar receivers operate in air, these coatings have long term stability issues that add to the operating costs of CSP facilities. Ideal absorbers must have high solar absorptance (>0.95) and low thermal emittance (<0.05) in the IR region, be stable in air, and be low-cost and readily manufacturable. We propose to utilize solution-based synthesis techniques to prepare intrinsic absorbers for use in central receiver applications.

  18. Application of dental nanomaterials: potential toxicity to the central nervous system.

    Science.gov (United States)

    Feng, Xiaoli; Chen, Aijie; Zhang, Yanli; Wang, Jianfeng; Shao, Longquan; Wei, Limin

    2015-01-01

    Nanomaterials are defined as materials with one or more external dimensions with a size of 1-100 nm. Such materials possess typical nanostructure-dependent properties (eg, chemical, biological, optical, mechanical, and magnetic), which may differ greatly from the properties of their bulk counterparts. In recent years, nanomaterials have been widely used in the production of dental materials, particularly in light polymerization composite resins and bonding systems, coating materials for dental implants, bioceramics, endodontic sealers, and mouthwashes. However, the dental applications of nanomaterials yield not only a significant improvement in clinical treatments but also growing concerns regarding their biosecurity. The brain is well protected by the blood-brain barrier (BBB), which separates the blood from the cerebral parenchyma. However, in recent years, many studies have found that nanoparticles (NPs), including nanocarriers, can transport through the BBB and locate in the central nervous system (CNS). Because the CNS may be a potential target organ of the nanomaterials, it is essential to determine the neurotoxic effects of NPs. In this review, possible dental nanomaterials and their pathways into the CNS are discussed, as well as related neurotoxicity effects underlying the in vitro and in vivo studies. Finally, we analyze the limitations of the current testing methods on the toxicological effects of nanomaterials. This review contributes to a better understanding of the nano-related risks to the CNS as well as the further development of safety assessment systems.

  19. Strategies for Reducing Energy Consumption in a Student Cafeteria in a Hot-Humid Climate: A Case Study

    Directory of Open Access Journals (Sweden)

    Mohammed Alhaji Mohammed

    2013-03-01

    Full Text Available Increasing attention is being given to energy consumption and potential for energy savings in public buildings in order to improve energy performance. Due to their size and functional requirements, public buildings especially cafeteria facilities tend to consume a significant amount of energy. Furthermore, due to their operational characteristics and construction pattern, unnecessary energy is likely to be used for maintaining acceptable indoor environmental quality. In this study, a student cafeteria at King Fahd University of Petroleum and Minerals, Saudi Arabia, was selected for the assessment of its energy performance and potential energy conservation opportunities. Energy simulation software Visual DOE 4.1 was used to develop an energy performance model for assessing various energy conservation measures pertinent to the building envelope and HVAC system design. Data required for setting up the model were gathered through simple energy audits. The architectural and mechanical drawings and the history of electrical consumption were collected. Various energy conservation strategies were then implemented including standards, single and combined energy conservation measures. These measures resulted in a combined design saving of 27.4%, the HVAC system saving 10.6%, implementation of standards saving about 16.7%, lighting 6.6%, equipment 2.6%, insulation 2.5% and glazing 1.4%. Based on these results, it is apparent that there is a significant potential for improving energy performance and justification to employ the suggested measures for achieving substantial energy savings and minimize energy consumption.

  20. Middle School Cafeteria Food Choice and Waste Prior to Implementation of Healthy, Hunger-Free Kids Act Changes in the National School Lunch Program

    Science.gov (United States)

    Connors, Priscilla; Bednar, Carolyn

    2015-01-01

    Purpose/Objectives: The study objective was to document choices of entrées, vegetables, fruits, grains/breads, and beverages on lunch trays and to determine the amount of each that was discarded after mealtime. Methods: A convenience sample of two urban middle school cafeterias in Texas participated in the study which took place in the 2010-2011…

  1. Effects of the cafeteria diet on the salivary glands of trained and sedentary Wistar rats - doi: 10.4025/actascibiolsci.v34i1.7473

    Directory of Open Access Journals (Sweden)

    Maria Raquel Marçal Natali

    2011-11-01

    Full Text Available The objective of this work was to study the effect of the aerobic physical training and the cafeteria diet introduced after weaning of Wistar rats and on the morphology of the main salivary glands (parotid, submandibular, sublingual. Male rats after weaning were subjected to the cafeteria diet or the standard rodent chow, and either performed aerobic physical training in a treadmill for 100 days, or did not performed any physical activity. Analyses were done considering the response in body weight, adipose tissues and salivary glands, and the data were submitted to statistical treatment (p < 0.05. The morphological and morphometric analyses of the salivary glands were performed through histological sections stained with hematoxylin and eosin. Despite the normophagic behavior, the rodents fed with the cafeteria diet became obese, with repercussions on parotid gland weight. However, this obesity and/or physical training did not influence the histological organization of the salivary glands. The morphometric analysis of the submandibular glands pointed out a reduction in the levels of serous acinar cells as an effect of the diet and physical training. In conclusion, the parotid and the submandibular glands alter themselves due to the nature and consistency of food present in the cafeteria diet as well as due to the aerobic physical training.

  2. Impact of a cafeteria diet and daily physical training on the rat serum metabolome

    Science.gov (United States)

    Suárez-García, Susana; del Bas, Josep M.; Caimari, Antoni; Escorihuela, Rosa M.; Arola, Lluís; Suárez, Manuel

    2017-01-01

    Regular physical activity and healthy dietary patterns are commonly recommended for the prevention and treatment of metabolic syndrome (MetS), which is diagnosed at an alarmingly increasing rate, especially among adolescents. Nevertheless, little is known regarding the relevance of physical exercise on the modulation of the metabolome in healthy people and those with MetS. We have previously shown that treadmill exercise ameliorated different symptoms of MetS. The aim of this study was to investigate the impact of a MetS-inducing diet and different intensities of aerobic training on the overall serum metabolome of adolescent rats. For 8 weeks, young rats were fed either standard chow (ST) or cafeteria diet (CAF) and were subjected to a daily program of training on a treadmill at different speeds. Non-targeted metabolomics was used to identify changes in circulating metabolites, and a combination of multivariate analysis techniques was implemented to achieve a holistic understanding of the metabolome. Among all the identified circulating metabolites influenced by CAF, lysophosphatidylcholines were the most represented family. Serum sphingolipids, bile acids, acylcarnitines, unsaturated fatty acids and vitamin E and A derivatives also changed significantly in CAF-fed rats. These findings suggest that an enduring systemic inflammatory state is induced by CAF. The impact of physical training on the metabolome was less striking than the impact of diet and mainly altered circulating bile acids and glycerophospholipids. Furthermore, the serum levels of monocyte chemoattractant protein-1 were increased in CAF-fed rats, and C-reactive protein was decreased in trained groups. The leptin/adiponectin ratio, a useful marker of MetS, was increased in CAF groups, but decreased in proportion to training intensity. Multivariate analysis revealed that ST-fed animals were more susceptible to exercise-induced changes in metabolites than animals with MetS, in which moderate

  3. Chronic intake of a cafeteria diet and subsequent abstinence. Sex-specific effects on gene expression in the mesolimbic reward system.

    Science.gov (United States)

    Ong, Zhi Yi; Wanasuria, Ayumi F; Lin, Mark Z P; Hiscock, Jennifer; Muhlhausler, Beverly S

    2013-06-01

    Studies examining the impact of chronic palatable food intake on the mesolimbic reward system have been conducted almost exclusively in males. This study aimed to determine the effects of chronic intake of a palatable cafeteria diet and subsequent abstinence on fat mass, food intake and key gene expression of the mesolimbic reward system in both males and females. Albino Wistar rats were fed for 8 weeks on standard chow (Control, n=5 males, 5 females) or cafeteria diet (CD; n=16 males, 16 females). The cafeteria diet was then removed from a subset of CD rats for 72 h (CD-Withdrawal group, CD-W). The nucleus accumbens (NAc) was isolated and mRNA expression of tyrosine hydroxylase (TH), dopamine active transporter (DAT), D1 and D2 dopamine receptors, and μ-opioid receptor determined by qRT-PCR. Chronic cafeteria diet intake increased fat mass in all CD rats but body weight and chow intake were reduced during the period of cafeteria diet abstinence. TH mRNA was reduced in male CD and CD-W rats, but increased in female CD and CD-W rats. D1 mRNA was reduced in CD and CD-W females, but increased in CD males, compared to Controls. μ-opioid receptor expression was reduced in CD and CD-W males but not females. These data highlight the importance of investigating sex differences in the neurobiological response to palatable food intake and the need for future studies in this area to include both sexes.

  4. Effects of long-term cycling between palatable cafeteria diet and regular chow on intake, eating patterns, and response to saccharin and sucrose.

    Science.gov (United States)

    Martire, Sarah I; Westbrook, R Fred; Morris, Margaret J

    2015-02-01

    When exposed to a diet containing foods that are rich in fat and sugar, rats eat to excess and gain weight. We examined the effects of alternating this diet with laboratory chow on intake of each type of diet, the eating elicited by a palatable food (biscuits), and the drinking elicited by sweet solutions that did (sucrose) or did not (saccharin) contain calories. Each week for 13 weeks, cycled rats were provided with the cafeteria diet for three successive days/nights and the chow diet for the remaining four days/nights, whereas other rats received continuous access to either the cafeteria or the chow diets. On each of the 13 weeks, cycled rats ate more across the first 24 hour exposure to the cafeteria diet than rats continuously fed this diet. In contrast, cycled rats ate less across the first 24 hour exposure to the chow diet than rats continuously fed this diet and ate less when presented a novel palatable biscuit than chow-fed rats. The three groups exhibited similar licks per cluster to saccharin, but cafeteria-fed and cycled rats showed fewer clusters than chow-fed rats. In contrast, chow-fed rats and cycled rats exhibited more licks per cluster to sucrose than cafeteria-fed rats, but all three groups had a similar number of clusters. The results were discussed in relation to the effects of diet cycling on eating patterns, body weight, and 'wanting' and 'liking'. These findings with rats may have important implications for yo-yo dieting in people.

  5. A escola promovendo hábitos alimentares saudáveis: uma proposta metodológica de capacitação para educadores e donos de cantina escolar Promotion of healthy eating habits by schools: a methodological proposal for training courses for educators and school cafeteria owners

    Directory of Open Access Journals (Sweden)

    Bethsáida de Abreu Soares Schmitz

    2008-01-01

    Full Text Available O projeto A Escola Promovendo Hábitos Alimentares Saudáveis estimula, desde 2001 no Distrito Federal, Brasil, a formação de bons hábitos alimentares na comunidade escolar, no contexto da promoção de estilos de vida saudáveis e prevenção das doenças crônicas não- transmissíveis. Este trabalho apresenta e avalia uma metodologia desenvolvida em 2006, para capacitação de educadores do ensino infantil e fundamental até a 4ª série e donos de cantina escolar. As oficinas tiveram aulas expositivas, atividades práticas, jogos educativos, entre outros. Como indicadores de avaliação analisaram-se itens relacionados à ampliação e aplicabilidade dos conhecimentos, além da implantação dos 10 passos da cantina escolar saudável. As atividades pedagógicas propostas foram verificadas pela análise dos portfólios dos educadores. A avaliação geral foi positiva, houve ampliação dos conhecimentos (p The project entitled Promotion of Health Eating Habits by Schools, operating in the Federal District of Brazil since 2001, encourages good eating habits in the school community within the context of promoting healthy lifestyles and preventing chronic non-communicable diseases. The current article presents and analyzes a methodology to train preschool and elementary educators and school cafeteria owners. The workshops included theoretical classes, practical activities, and educational games and were evaluated on the basis of expansion and applicability of knowledge, in addition to implementation of the 10 steps to a healthy school cafeteria. The proposed pedagogical activities were verified by an analysis of the teachers' workshop folders. The overall evaluation was positive, with expansion of knowledge (p < 0.05 among participants for the three workshop modules. The objectives laid out in the workshop folders were reached by 44% of the teachers. In the implementation of the healthy cafeteria, positive results were observed when comparing

  6. Elimination of central line-associated bloodstream infections: application of the evidence.

    Science.gov (United States)

    Posa, Patricia J; Harrison, Denise; Vollman, Kathleen M

    2006-01-01

    Central line-associated bloodstream infections are considered to be an avoidable complication of care delivery. In addition to considerable morbidity and use of resources, central line-associated bloodstream infections carry an attributable morality between 12% and 25%. The estimated cost per infection is approximately 25,000 US dollars. Research over the last decade has focused on a number of care activities that have been shown to reduce the incidence of bloodstream infections related to central line placement in the critically ill patient. A significant reduction or elimination of central line-associated bloodstream infections can occur with implementation of a comprehensive central line-associated bloodstream infection prevention program that includes staff education, hand hygiene, use of maximal sterile barrier precautions, chlorhexidine gluconate skin antisepsis, avoidance of femoral lines, empowerment of staff to stop the procedure if sterile technique is broken, and daily assessment of the continued need for a central line. This article focuses on strategies for implementing a comprehensive central line-associated bloodstream infections prevention program and a tool and process for defect analysis as part of a statewide collaborative in Michigan.

  7. Statistical sulcal shape comparisons: application to the detection of genetic encoding of the central sulcus shape

    DEFF Research Database (Denmark)

    Le Goualher, G; Argenti, A.M.; Duyme, M;

    2000-01-01

    encoding. When applied to real data, this study highlighted genetic constraints on the shape of the central sulcus. We found from 10 pairs of monozygotic twins that the intrapair modal distance of the central sulcus was significantly smaller than the interpair modal distance, for both the left central...... sulcus (Z = -2.66; P sulcus (Z = -2.26; P sulcus shape were confirmed by applying the same experiment to 10 pairs of normal young individuals (Z = -1.39; Z = -0.63, i.e., values not significant at the P

  8. Correlation between centrality metrics and their application to the opinion model

    CERN Document Server

    Li, Cong; Van Mieghem, Piet; Stanley, H Eugene; Wang, Huijuan

    2014-01-01

    In recent decades, a number of centrality metrics describing network properties of nodes have been proposed to rank the importance of nodes. In order to understand the correlations between centrality metrics and to approximate a high-complexity centrality metric by a strongly correlated low-complexity metric, we ?first study the correlation between centrality metrics in terms of their Pearson correlation coefficient and their similarity in ranking of nodes. In addition to considering the widely used centrality metrics, we introduce a new centrality measure, the degree mass. The m order degree mass of a node is the sum of the weighted degree of the node and its neighbors no further than m hops away. We find that the B_{n}, the closeness, and the components of x_{1} are strongly correlated with the degree, the 1st-order degree mass and the 2nd-order degree mass, respectively, in both network models and real-world networks. We then theoretically prove that the Pearson correlation coefficient between x_{1} and th...

  9. Laser photobiomodulation as an adjunct of the wound healing impairment of rats exposed to a cafeteria diet

    Science.gov (United States)

    Uzeda, V.; Paraguassu, G. M.; Dos Santos, J. N.; Ramalho, M. J.; Rodriguez, T. T.; Ramalho, L. M. P.

    2014-02-01

    Obesity is associated to a delayed wound healing and prolonged inflammatory phase. Laser light has shown positive results in the photobiomodulation of tissue repair; however, its use associated with systemic disorders such as obesity is still little explored in the literature. The aim of this study was to validate an experimental system for studying weight gaining by consuming a high fat diet called "cafeteria diet" (CD) for the induction of obesity. Forty-eight rats were weaned, divided into two experimental groups: standard diet (SD) and Cafeteria Diet (CD). Free feeding was carried out during 20 weeks and the mass gaining was accompanied. After general anesthesia standardized surgical wounds were created (1cm2) in the dorsal midline region of each animal. Both groups (SD; CD) were divided into 2 subgroups of 12 animals, G1 and G3 (non-irradiated) and G2 and G4 (irradiated). The irradiation protocols (λ660 nm, 40 mW, CW; 24 J/cm2) started immediately after surgery and were repeated every other day during 14 days. The rats were killed at the 8th or 15th days after surgery. The abdominal fat was removed and weighed to verify the success of the induction technique. The specimens were taken and routinely processed histology (hematoxylin/eosin) was performed. It was concluded that the ingestion of fast-food increased abdominal fat in rats and modified the inflammatory pattern of the healing. Laser phototherapy in the parameters employed decreased inflammatory intensity quickening wound healing in obese rats.

  10. Influence of high-calorie (cafeteria) diets on the population of Paneth cells in the small intestine of the rat.

    Science.gov (United States)

    Becerril, Adriana; Castillo-Robles, Guadalupe; González-Hernández, Margarita; Villanueva, Iván

    2005-01-01

    A high-calorie (cafeteria) diet is known to cause changes in the intestinal morphology and functioning that seem to be related to calorie overfeeding. Among the cell lineages found in the small intestine epithelium, the Paneth cell (PC) population is known to be influenced by factors related mainly to the intestinal microbiota. The role of PCs in the intestinal cell concert remains unclear, because experimental evidence suggests PC involvement in local processes other than protection against pathogens. Participation of PC in digestive mechanisms has been proposed on this basis. We have analyzed the effect of high-carbohydrate (HC) and high-fat (HF) cafeteria diets on the PC population in the small intestine of the adult rat. For 8 weeks, both HC and HF diets caused a gain in body weight, but whereas the HC-fed rats showed reduced counts of intestinal crypts per 5-mum section, the HF-fed group showed the opposite. In control rats, the number of crypts per section showed a slight tendency to decrease along the duodenum - ileum axis, whereas the number of PCs per crypt was increased towards the ileum. As a result, the number of PCs per section (calculated from these data) remained constant along the three segments of the intestine. The hypercaloric diets did not modify the general tendencies seen in the crypt and PC counts, but reduced the number of PCs per section in the duodenum by 50%. HC-fed, but not HF-fed, rats showed a similar reduction in jejunum also. These changes do not correlate particularly with any of the predictable effects of diet composition, so that a multifactorial control of PC density is proposed.

  11. Behavioral characterization of a model of differential susceptibility to obesity induced by standard and personalized cafeteria diet feeding.

    Science.gov (United States)

    Gac, L; Kanaly, V; Ramirez, V; Teske, J A; Pinto, M P; Perez-Leighton, C E

    2015-12-01

    Despite the increase in obesity prevalence over the last decades, humans show large inter-individual variability for susceptibility to diet-induced obesity. Understanding the biological basis of this susceptibility could identify new therapeutic alternatives against obesity. We characterized behavioral changes associated with propensity to obesity induced by cafeteria (CAF) diet consumption in mice. We show that Balb/c mice fed a CAF diet display a large inter-individual variability in susceptibility to diet-induced obesity, such that based on changes in adiposity we can classify mice as obesity prone (OP) or obesity resistant (OR). Both OP and OR were hyperphagic relative to control-fed mice but caloric intake was similar between OP and OR mice. In contrast, OR had a larger increase in locomotor activity following CAF diet compared to OP mice. Obesity resistant and prone mice showed similar intake of sweet snacks, but OR ate more savory snacks than OP mice. Two bottle sucrose preference tests showed that OP decreased their sucrose preference compared to OR mice after CAF diet feeding. Finally, to test the robustness of the OR phenotype in response to further increases in caloric intake, we fed OR mice with a personalized CAF (CAF-P) diet based on individual snack preferences. When fed a CAF-P diet, OR increased their calorie intake compared to OP mice fed the standard CAF diet, but did not reach adiposity levels observed in OP mice. Together, our data show the contribution of hedonic intake, individual snack preference and physical activity to individual susceptibility to obesity in Balb/c mice fed a standard and personalized cafeteria-style diet.

  12. Network centrality measures and systemic risk: An application to the Turkish financial crisis

    Science.gov (United States)

    Kuzubaş, Tolga Umut; Ömercikoğlu, Inci; Saltoğlu, Burak

    2014-07-01

    In this paper, we analyze the performance of several network centrality measures in detecting systemically important financial institutions (SIFI) using data from the Turkish Interbank market during the financial crisis in 2000. We employ various network investigation tools such as volume, transactions, links, connectivity and reciprocity to gain a clearer picture of the network topology of the interbank market. We study the main borrower role of Demirbank in the crash of the banking system with network centrality measures which are extensively used in the network theory. This ex-post analysis of the crisis shows that centrality measures perform well in identifying and monitoring systemically important financial institutions which provide useful insights for financial regulations.

  13. Application of Canal Automation at the Central Arizona Irrigation and Drainage District

    Science.gov (United States)

    The Central Arizona Irrigation and Drainage District (CAIDD) began delivering water to users in 1987. Although designed for automatic control, the system was run manually until a homemade SCADA (Supervisory Control and Data Acquisition) system was developed by a district employee. In 2002, problem...

  14. Farmer evaluation of phosphorus fertilizer application to annual legumes in Chisepo, Central Malawi

    NARCIS (Netherlands)

    Kamanga, B.C.G.; Whitbread, A.M.; Wall, P.; Waddington, S.R.; Almekinders, C.J.M.; Giller, K.E.

    2010-01-01

    Building from the perception that farmers have an intimate knowledge of their local environment, production problems, crop priorities and criteria for evaluation, an on-farm experiment was conducted with farmers in 2003/4 in Chisepo, central Malawi, to evaluate the response of six annual legumes to

  15. Nourishing change. Partnership enlists dozens of hospitals to put healthier food on their menus and kick junk food out of the cafeteria.

    Science.gov (United States)

    Lee, Jaimy

    2012-10-08

    More than 150 hospitals have signed on to the Partnership for a Healthier America's push to ditch the deep-fat fryer in their cafeterias and bulk up on fruit and veggies. "Our focus is to ensure that if people want to make a healthy choice, they can," says Larry Soler, left, president and CEO of the partnership, which is working to reduce childhood obesity.

  16. Development and application of the decision support system for municipal solid waste management in central Taiwan.

    Science.gov (United States)

    Chang, Yao-Jen; Lin, Min-Der

    2013-05-01

    Municipal solid waste management (MSWM) is an important, practical and challenging environmental subject. The processes of a MSWM system include household collection, transportation, treatment, material recycling, compost and disposal. A regional program of MSWM is more complicated owing to the involvement of multi-municipality and multi-facility issues. Therefore, an effective decision support system capable of solving regional MSWM problems is necessary for decision-makers. This article employs linear programming techniques to establish a MSWM decision support system (MSWM-DSS) that is able to determine the least costs of regional MSWM strategies. The results of investigating a real-world case in central Taiwan indicate that a regional program is more economical and efficient. For the redeployment of MSW streams, the relatively least cost of operation for the MSWM system can still be achieved through the re-estimation of the MSWM-DSS. This tool and results are useful for MSWM policy-making in central Taiwan.

  17. Central Colorado Assessment Project - Application of integrated geologic, geochemical, biologic, and mineral resource studies

    Science.gov (United States)

    Klein, T.L.; Church, S.E.; Caine, J.S.; Schmidt, T.S.; deWitt, E.H.

    2008-01-01

    Central Colorado is one of the fastest-growing regions in the Western United States. Population along the Front Range increased more than 30 percent between 1990 and 2000 (http://www.demographia.com/db-metro3newworld.htm) with some counties within the study area, such as Park County, experiencing greater than 100-percent growth (http://www.censusscope.org/us/s8/rank_popl_growth.html). This growth has caused tremendous demand for natural resources and has created challenging land-management issues related to the interface between wilderness and urban expansion. Management of this wilderness/urban interface will benefit from current digital geoscience information collected by the U.S. Geological Survey (USGS) Central Colorado Assessment Project that began in 2003. Approximately 20,800 square miles (53,800 km2) of land divided almost equally between the public and private sectors were part of the assessment.

  18. Independent Accounting and Balance of Payments of Hospital Cafeteria%浅谈医院食堂独立核算与收支平衡

    Institute of Scientific and Technical Information of China (English)

    汤有为; 杨艳; 高晓丽

    2013-01-01

    With the deepening of reform of the health care system, the cost consciousness is growing in hospitals. It is of greater importance for hospitals to establish complete financial and management systems to achieve balance of payments and reduce cost pressure. The cafeteria is a unique part of hospital. Due to lack of complete financial management systems, most cafeterias are losing money. It is proposed that independent accounting should be introduced, in order to strengthen the financial management and gradually achieve balance of payments of hospital cafeteria and facilitate the dinning of hospital staffs.%随着医疗卫生体制改革的深入,医院的成本意识逐步增强,为缓解医院的成本压力,建立完善的财务和管理制度实现医院收支平衡越来越受到医院的重视。医院食堂是医院的一个特殊部门,由于缺乏完善的财务管理制度,医院食堂多出现亏损,文章提出应通过独立核算,加强财务管理,逐步实现医院食堂的收支平衡,保证医院职工就餐方便。

  19. The application of Kyoto Protocol in Italy: role and required synergies between central and regional administrations

    Directory of Open Access Journals (Sweden)

    Pilli R

    2007-01-01

    Full Text Available According to art. 3.3 of the Kyoto Protocol, Parties included in Annex I shall report the net changes in greenhouse gas emissions by sources and removals by sinks resulting from afforestation, reforestation and deforestation activities. To assess these activities, Italy has to define methods to estimate land use change occurring after 31 December 1989. On the other hand, Italy elected forest management as additional human-induced activity to attain the goals of reduction of greenhouse gas emissions. The paper considers the key-role that central and regional Administrations may have in order to solve some specific problems regarding data collection and management issues.

  20. Gases dissolved in groundwaters: analytical methods and examples of applications in central Italy

    Energy Technology Data Exchange (ETDEWEB)

    Chiodini, G. [Osservatorio Vesuviano, Napoli (Italy)

    1998-12-31

    A quick method to analyse dissolved gases in natural waters is described. First partial results show that useful information on the geochemical processes affecting a variety of hydrogeological systems can be obtained from the study of dissolved gases. The study of the CO{sub 2} dissolved in the groundwaters of Central Italy indicates that one of the main factor controlling the P{sub CO2} values in these groundwaters is the input of a deeply originated gas phase. These leakage processes generally occur in correspondence with buried structural highs of the carbonate basement acting as both traps for the gas produced at depth and sources of high CO{sub 2} fluxes toward the surface. This CO{sub 2} causes significant increases in the P{sub {sub O}2} values of shallow groundwaters. The total carbon balance of two regional aquifers has been used to estimate the production rate of deep CO{sub 2} in Tyrrhenian Central Italy. These average production rates, with 5 X 10{sup 6}mol km{sup -2} y{sup -1} both at Stifone and at Colli Albani, are five times higher than the value assumed as baseline for areas of high heat flow, i.e., 10{sup 6} km{sup -2} y{sup -1}.

  1. Application of Targeted Mass Spectrometry for the Quantification of Sirtuins in the Central Nervous System

    Science.gov (United States)

    Jayasena, T.; Poljak, A.; Braidy, N.; Zhong, L.; Rowlands, B.; Muenchhoff, J.; Grant, R.; Smythe, G.; Teo, C.; Raftery, M.; Sachdev, P.

    2016-10-01

    Sirtuin proteins have a variety of intracellular targets, thereby regulating multiple biological pathways including neurodegeneration. However, relatively little is currently known about the role or expression of the 7 mammalian sirtuins in the central nervous system. Western blotting, PCR and ELISA are the main techniques currently used to measure sirtuin levels. To achieve sufficient sensitivity and selectivity in a multiplex-format, a targeted mass spectrometric assay was developed and validated for the quantification of all seven mammalian sirtuins (SIRT1-7). Quantification of all peptides was by multiple reaction monitoring (MRM) using three mass transitions per protein-specific peptide, two specific peptides for each sirtuin and a stable isotope labelled internal standard. The assay was applied to a variety of samples including cultured brain cells, mammalian brain tissue, CSF and plasma. All sirtuin peptides were detected in the human brain, with SIRT2 being the most abundant. Sirtuins were also detected in human CSF and plasma, and guinea pig and mouse tissues. In conclusion, we have successfully applied MRM mass spectrometry for the detection and quantification of sirtuin proteins in the central nervous system, paving the way for more quantitative and functional studies.

  2. Application of Central Upwind Scheme for Solving Special Relativistic Hydrodynamic Equations.

    Directory of Open Access Journals (Sweden)

    Muhammad Yousaf

    Full Text Available The accurate modeling of various features in high energy astrophysical scenarios requires the solution of the Einstein equations together with those of special relativistic hydrodynamics (SRHD. Such models are more complicated than the non-relativistic ones due to the nonlinear relations between the conserved and state variables. A high-resolution shock-capturing central upwind scheme is implemented to solve the given set of equations. The proposed technique uses the precise information of local propagation speeds to avoid the excessive numerical diffusion. The second order accuracy of the scheme is obtained with the use of MUSCL-type initial reconstruction and Runge-Kutta time stepping method. After a discussion of the equations solved and of the techniques employed, a series of one and two-dimensional test problems are carried out. To validate the method and assess its accuracy, the staggered central and the kinetic flux-vector splitting schemes are also applied to the same model. The scheme is robust and efficient. Its results are comparable to those obtained from the sophisticated algorithms, even in the case of highly relativistic two-dimensional test problems.

  3. Normative equations for central augmentation index: assessment of inter-population applicability and how it could be improved.

    Science.gov (United States)

    Jeroncic, Ana; Gunjaca, Grgo; Mrsic, Danijela Budimir; Mudnic, Ivana; Brizic, Ivica; Polasek, Ozren; Boban, Mladen

    2016-05-27

    Common reference values of arterial stiffness indices could be effective screening tool in detecting vascular phenotypes at risk. However, populations of the same ethnicity may differ in vascular phenotype due to different environmental pressure. We examined applicability of normative equations for central augmentation index (cAIx) derived from Danish population with low cardiovascular risk on the corresponding Croatian population from the Mediterranean area. Disagreement between measured and predicted cAIx was assessed by Bland-Altman analysis. Both, cAIx-age distribution and normative equation fitted on Croatian data were highly comparable to Danish low-risk sample. Contrarily, Bland-Altman analysis of cAIx disagreement revealed a curvilinear deviation from the line of full agreement indicating that the equations were not equally applicable across age ranges. Stratification of individual data into age decades eliminated curvilinearity in all but the 30-39 (men) and 40-49 (women) decades. In other decades, linear disagreement independent of age persisted indicating that cAIx determinants other than age were not envisaged/compensated for by proposed equations. Therefore, established normative equations are equally applicable to both Nordic and Mediterranean populations but are of limited use. If designed for narrower age ranges, the equations' sensitivity in detecting vascular phenotypes at risk and applicability to different populations could be improved.

  4. Risk of hypertension in Yozgat Province, Central Anatolia: application of Framingham Hypertension Prediction Risk Score.

    Science.gov (United States)

    Kilic, M; Ede, H; Kilic, A I

    2016-07-10

    The aim of this cross-sectional study was to estimate the risk of hypertension in 1106 Caucasian individuals aged 20-69 years in Yozgat Province, using the Framingham Hypertension Risk Prediction Score (FHRPS). According to FHRPS, average risk of developing hypertension over 4 years was 6.2%. The participants were classified into low- (10%) risk groups. The percentage of participants that fell into these groups was 59.4%, 19.8% and 20.8% respectively. The proportion of participants in the high-risk group was similar to the 4-year incidence of hypertension (21.3%) in the Turkish population. Regression analysis showed that high salt consumption and low educational level significantly increased the risk of hypertension. Economic level, fat consumption, life satisfaction, physical activity, and fruit and vegetable consumption were not correlated with risk of hypertension. This study shows that FHRPS can also be used for predicting risk of hypertension in Central Anatolia.

  5. Dynamic disturbance rejection controllers for neutral time delay systems with application to a central heating system

    Institute of Scientific and Technical Information of China (English)

    KOUMBOULIS Fotis N.; KOUVAKAS Nikolaos D.; PARASKEVOPOULOS Paraskevas N.

    2009-01-01

    In the present paper the problem of disturbance rejection of single input-single output neutral time delay systems with multiple measurable disturbances is solved via dynamic controllers. In particular, the general form of the controller matrices is presented, while the necessary and sufficient conditions for the controller to be realizable are offered. The proposed technique is applied to a test case neutral time delay central heating system. In particular, the nonlinear model of the plant and its linearized approximation are presented. Based on the linearized model, a two-stage controller is designed in order to regulate the room temperature and the boiler effluent temperature. The performance of the closed loop system is investigated through computational experiments.

  6. On Space Design of Western-style Cafeteria%西式餐厅的空间设计

    Institute of Scientific and Technical Information of China (English)

    罗维安

    2012-01-01

      社会发展的今天,餐饮已经成为人们追求物质与精神享受的重要体现,因此餐饮业的发展也呈日新月异之态。西方餐饮文化的迅速传播,不仅为中国的餐饮业注入了新的元素,而且迎合了人们的餐饮消费观念;西方餐饮文化的融入刺激了中国餐厅展示空间设计的革新。以西式餐厅为基点,探讨了西式餐厅的空间设计内涵。%  Abstact: Nowadays, catering has become a very important manifestation of people’s pursuit of material and spiritual enjoyment. Meanwhile, catering is undergoing renovation day by day. One of the renovations is that western catering culture has been disseminating widely across China, which has not only added new elements to the traditional Chinese catering culture, but also catered for people’s dining concept. The integration of the western catering culture has stimulated the renovation of the displaying space decoration. This essay analyzes the internal factors regarding the design of the displaying space in western-style cafeteria.

  7. Diffusion centrale des rayons X sous incidence rasante. Faisabilité et applications

    Science.gov (United States)

    Naudon, A.; Goudeau, P.; Slimani, T.

    1992-06-01

    The small-angle X-ray scattering (SAXS) intensity obtained in the transmission mode is very weak for a thin layer having a thickness of some tens nanometers, but when this layer is studied under grazing-incidnece the scattering can be measured with a good signal-to-background ratio. Fruthermore, for a bulk sample, grazing-incidence is the only way to study the surface layer, and, by successive abrasions of the surface, to analyse at each time a thin layer at a chosen depth. We show this possibility with Guinier-Preston zones in quenched Al-Ag alloys where the size of the GP zones varies from the surface to the depth of a thick sample, according to the quenching rate. For a tungsten-carbon coating on a stainless steel we are able to measure small precipitates on the 100 nm thick surface layer. These examples show that small-angle X-ray scattering under grazing-incidence is a non destructive method for studying heterogeneities on a nanoscale which can be encountered in thin layers. Si pour une couche mince de quelques dizaines de nanomètres d'épaisseur, le signal de diffusion centrale obtenu de façon classique en transmission est faible, il en est autrement avec l'incidence rasante, où l'on peut éclairer une grande surface et obtenir un bon rapport signal sur bruit. De plus, pour un échantillon massif, á condition qu'il soit plan, la diffusion centrale en incidence rasante permet d'étudier les hét`'erogénéités sur une très faible épaisseur. Par abrasions successives on peut suivre la variation de paramètres structuraux en fonction de l'épaisseur. Nous montrons ces possiblités dans le cas des zones de Guinier-Preston d'alliages Al-Ag trempés dont les tailles varient de façon significative entre la surface et le coeur de l'échantillon. Nous pouvons alors établir la relation entre la vitesse de trempe et les tailles obtenues dans des tranches de 1 micron d'épaisseur. Pour un acier recouvert d'une couche de carbone-tungstène on peut mesurer la

  8. Application of the central composite design to optimize the preparation of novel micelles of harmine

    Directory of Open Access Journals (Sweden)

    Bei YY

    2013-05-01

    Full Text Available Yong-Yan Bei,1,* Xiao-Feng Zhou,2,3,* Ben-Gang You,1 Zhi-Qiang Yuan,1 Wei-Liang Chen,1 Peng Xia,1 Yang Liu,1 Yong Jin,4 Xiao-Juan Hu,1 Qiao-Ling Zhu,1 Chun-Ge Zhang,1 Xue-Nong Zhang,1 Liang Zhang5 1Department of Pharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou 215123, People’s Republic of China; 2College of Radiological Medicine and Protection, Soochow University, Suzhou, People’s Republic of China; 3Changshu Hospital of Traditional Chinese Medicine, Changshu, People’s Republic of China; 4Invasive Technology Department, The Second Affiliated Hospital of Soochow University, Suzhou, People’s Republic of China; 5Department of Biopharmaceutics, College of Pharmaceutical Sciences, Soochow University, Suzhou, People’s Republic of China*These authors contributed equally to the paperAbstract: Lactose–palmitoyl–trimethyl–chitosan (Lac-TPCS, a novel amphipathic self-assembled polymer, was synthesized for administration of insoluble drugs to reduce their adverse effects. The central composite design was used to study the preparation technique of harmine (HM-loaded self-assembled micelles based on Lac-TPCS (Lac-TPCS/HM. Three preparation methods and single factors were screened, including solvent type, HM amount, hydration volume, and temperature. The optimal preparation technique was identified after investigating the influence of two independent factors, namely, HM amount and hydration volume, on four indexes, ie, encapsulation efficiency (EE, drug-loading amount (LD, particle size, and polydispersity index (PDI. Analysis of variance showed a high coefficient of determination of 0.916 to 0.994, thus ensuring a satisfactory adjustment of the predicted prescription. The maximum predicted values of the optimal prescription were 91.62%, 14.20%, 183.3 nm, and 0.214 for EE, LD, size, and PDI, respectively, when HM amount was 1.8 mg and hydration volume was 9.6 mL. HM-loaded micelles were successfully characterized by

  9. Basic Aspects of the Pharmacodynamics of Tolperisone, A Widely Applicable Centrally Acting Muscle Relaxant

    OpenAIRE

    Tekes, Kornelia

    2014-01-01

    Tolperisone (2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one hydro-chloride) was introduced in the clinical practice more than forty years ago and is still evaluated as a widely applicable compound in pathologically elevated skeletal muscle tone (spasticity) and related pains of different origin. In the present review, basic pharmacodynamic effects measured on whole animals, analyses of its actions on cell and tissue preparations and molecular mechanism of action on sodium and calciu...

  10. Development and application of microsatellites in Carcinus maenas: genetic differentiation between Northern and Central Portuguese populations.

    Directory of Open Access Journals (Sweden)

    Sónia Pascoal

    Full Text Available Carcinus maenas, the common shore crab of European coastal waters, has recently gained notoriety due to its globally invasive nature associated with drastic ecological and economic effects. The native ubiquity and worldwide importance of C. maenas has resulted in it becoming one of the best-studied estuarine crustacean species globally. Accordingly, there is significant interest in investigating the population genetic structure of this broadly distributed crab along European and invaded coastlines. Here, we developed polymerase chain reaction (PCR primers for one dinucleotide and two trinucleotide microsatellite loci, resulting from an enrichment process based on Portuguese populations. Combining these three new markers with six existing markers, we examined levels of genetic diversity and population structure of C. maenas in two coastal regions from Northern and Central Portugal. Genotypes showed that locus polymorphism ranged from 10 to 42 alleles (N = 135 and observed heterozygosity per locus ranged from 0.745 to 0.987 with expected heterozygosity ranging from 0.711 to 0.960; values typical of marine decapods. The markers revealed weak, but significant structuring among populations (global F(ST = 0.004 across a 450 km (over-water distance spatial scale. Combinations of these and existing markers will be useful for studying population genetic parameters at a range of spatial scales of C. maenas throughout its expanding species range.

  11. Application of scientific core drilling to geothermal exploration: Platanares, Honduras and Tecuamburro Volcano, Guatemala, Central America

    Energy Technology Data Exchange (ETDEWEB)

    Goff, S.J.; Goff, F.E.; Heiken, G.H. [Los Alamos National Lab., NM (United States); Duffield, W.A. [Geological Survey, Flagstaff, AZ (United States); Janik, C.J. [Geological Survey, Menlo Park, CA (United States)

    1994-04-01

    Our efforts in Honduras and Guatemala were part of the Central America Energy Resource Project (CAERP) funded by the United States Agency for International Development (AID). Exploration core drilling operations at the Platanares, Honduras and Tecuamburro Volcano, Guatemala sites were part of a geothermal assessment for the national utility companies of these countries to locate and evaluate their geothermal resources for electrical power generation. In Honduras, country-wide assessment of all thermal areas determined that Platanares was the site with the greatest geothermal potential. In late 1986 to middle 1987, three slim core holes were drilled at Platanares to a maximum depth of 680 m and a maximum temperature of 165{degree}C. The objectives were to obtain information on the geothermal gradient, hydrothermal alterations, fracturing, and possible inflows of hydrothermal fluids. Two holes produced copious amounts of water under artesian conditions and a total of 8 MW(t) of energy. Geothermal investigations in Guatemala focused on the Tecuamburro Volcano geothermal site. The results of surface geological, volcanological, hydrogeochemical, and geophysical studies at Tecuamburro Volcano indicated a substantial shallow heat source. In early 1990 we drilled one core hole, TCB-1, to 808 m depth. The measured bottom hole temperature was 238{degree}C. Although the borehole did not flow, in-situ samples indicate the hole is completed in a vapor-zone above a probable 300{degree}C geothermal reservoir.

  12. Application of synchrotron radiation for elemental microanalysis of human central nervous system tissue

    Energy Technology Data Exchange (ETDEWEB)

    Szczerbowska-Boruchowska, M.; Lankosz, M.; Ostachowicz, J. [Mining University, Dept. of Radipmetry, Faculty of Physics and Nuclear Techniques, Krakow (Poland); Adamek, D.; Krygowska-Wajs, A.; Tomik, B.; Szczudlik, A. [Jagiellonian University, Institute of Neurology, Collegium Medicum, Krakow (Poland); Simionovici, A.; Bohic, S. [European Synchrotron Radiation Facility ESRF, 38 - Grenoble (France)

    2002-08-01

    The pathogenesis of two neuro-degenerative diseases i.e, Parkinson's Disease (PD) and amyotrophic lateral sclerosis (ALS) are still not known. It is supposed that disturbance of metal ions homeostasis may promote degeneration and atrophy of neurons. As a preliminary study, the quantitative and topographic elemental analysis of selected parts of human brain and spinal cord was performed using synchrotron microbeam-X ray fluorescence ({mu}-SXRF) technique. The samples were taken during the autopsy from patients with PD, ALS and from patients died due to non-neurological conditions events. X-ray fluorescence imaging showed that increased concentration of selected elements are observed in neurons perikaryal parts in compare with surrounding area. Moreover, comparable analysis showed significant differences in accumulation of selected elements between the pathological and control case. The investigations indicate that micro-beam of synchrotron radiation can be satisfactory applied for analysis of central nervous system tissue providing useful information about distribution and contents of elements at the single cell level. (authors)

  13. Basic aspects of the pharmacodynamics of tolperisone, a widely applicable centrally acting muscle relaxant.

    Science.gov (United States)

    Tekes, Kornelia

    2014-01-01

    Tolperisone (2-methyl-1-(4-methylphenyl)-3-piperidin-1-ylpropan-1-one hydro-chloride) was introduced in the clinical practice more than forty years ago and is still evaluated as a widely applicable compound in pathologically elevated skeletal muscle tone (spasticity) and related pains of different origin. In the present review, basic pharmacodynamic effects measured on whole animals, analyses of its actions on cell and tissue preparations and molecular mechanism of action on sodium and calcium channels are summarized as recently significantly new data were reported.

  14. Application of Central Composite Design in Optimization of Valsartan Nanosuspension to Enhance its Solubility and Stability.

    Science.gov (United States)

    Vuppalapati, Lavakumar; Cherukuri, Sowmya; Neeli, Vijaykumar; Yeragamreddy, Padmanabha Reddy; Kesavan, Bhaskar Reddy

    2016-01-01

    The objective of the present research is to prepare stable nano suspensions of Valsartan (VAL) with high solubility and dissolution. VAL is an orally administered anti-hypertensive drug with lower bio-availability of 25%, this is attributed to its lower aqueous solubility (0.082 mg/ml). VAL nano suspensions were prepared by using a bottom-up precipitation technique using five level full factorial central composite design (CCD). The optimized nano formulations NS21, NS22, NS23 showed the particle size of 268.42±8.99, 288.3±11.32, 293.46±6.92 nm, zeta potential of 20.89±0.79, 26.01 ±1.02, 21.34±0.43 mVs and the dissolution efficiency of 93.10±1.459, 91.84±1.419, 89.47±0.644 % respectively. SEM & AFM studies represent the formation of fine irregularly shaped particles with smooth surfaces on nanosization. X-rd studies confirmed the physical state conversion of crystalline drug into amorphous form. Drug excipient compatibility was studied using differential scanning calorimetry (DSC) and Fourier transform infrared spectroscopy (FT-IR). The investigation pragmatic the solubility and dissolution efficiency of VAL in nanosuspension was significantly higher when compared with its pure form. Finally, it is concluded that, nanosuspension approach could be an ideal, promising approach to increase the solubility and dissolution of BCS-II drugs like Valsartan.

  15. Evaluation and application of the ROMS 1-way embedding procedure to the central california upwelling system

    Science.gov (United States)

    Penven, Pierrick; Debreu, Laurent; Marchesiello, Patrick; McWilliams, James C.

    What most clearly distinguishes near-shore and off-shore currents is their dominant spatial scale, O (1-30) km near-shore and O (30-1000) km off-shore. In practice, these phenomena are usually both measured and modeled with separate methods. In particular, it is infeasible for any regular computational grid to be large enough to simultaneously resolve well both types of currents. In order to obtain local solutions at high resolution while preserving the regional-scale circulation at an affordable computational cost, a 1-way grid embedding capability has been integrated into the Regional Oceanic Modeling System (ROMS). It takes advantage of the AGRIF (Adaptive Grid Refinement in Fortran) Fortran 90 package based on the use of pointers. After a first evaluation in a baroclinic vortex test case, the embedding procedure has been applied to a domain that covers the central upwelling region off California, around Monterey Bay, embedded in a domain that spans the continental U.S. Pacific Coast. Long-term simulations (10 years) have been conducted to obtain mean-seasonal statistical equilibria. The final solution shows few discontinuities at the parent-child domain boundary and a valid representation of the local upwelling structure, at a CPU cost only slightly greater than for the inner region alone. The solution is assessed by comparison with solutions for the whole US Pacific Coast at both low and high resolutions and to solutions for only the inner region at high resolution with mean-seasonal boundary conditions.

  16. Central Nervous System Disease in Hematological Malignancies: Historical Perspective and Practical Applications

    Science.gov (United States)

    Pui, Ching-Hon; Thiel, Eckhard

    2009-01-01

    Acute lymphoblastic leukemia (ALL) 5-year survival rates are approaching 90% in children and 50% in adults who are receiving contemporary risk-directed treatment protocols. Current efforts focus not only on further improving cure rate but also on patient quality of life. Hence, all protocols decrease or limit the use of cranial irradiation as central nervous system (CNS)-directed therapy, even in patients with high-risk presenting features, such as the presence of leukemia cells in the cerebrospinal fluid (even resulting from traumatic lumbar puncture), adverse genetic features, T-cell immunophenotype, and a large leukemia-cell burden. Current strategies for CNS-directed therapy involve effective systemic chemotherapy (eg, dexamethasone, high-dose methotrexate, intensive asparaginase, ifosfamide) and early intensification and optimization of intrathecal therapy. Options under investigation for the treatment of relapsed or refractory CNS leukemia in ALL patients include thiotepa and intrathecal liposomal cytarabine. CNS involvement in non-Hodgkin’s lymphoma (NHL) is associated with young age, advanced stage, number of extranodal sites, elevated lactate dehydrogenase, and International Prognostic Index score. Refractory CNS lymphoma in patients with NHL carries a poor prognosis, with a median survival of 2 to 6 months; the most promising treatment, autologous stem cell transplant, can extend median survival from 10 to 26 months. CNS prophylaxis is required during the initial treatment of NHL subtypes that carry a high risk of CNS relapse, such as B-cell ALL, Burkitt’s lymphoma, and lymphoblastic lymphoma. The use of CNS prophylaxis in the treatment of diffuse large B-cell lymphoma is controversial because of the low risk of CNS relapse (~5%) in this population. In this article, we review current and past practice of intrathecal therapy in ALL and NHL and the risk-models that aim to identify predictors of CNS relapse in NHL. PMID:19660680

  17. Application of solar energy in heating and cooling of residential buildings under Central Asian conditions

    Directory of Open Access Journals (Sweden)

    Usmonov Shukhrat Zaurovich

    2014-04-01

    Full Text Available Solar radiation is the main source of thermal energy for almost all the processes developing in the atmosphere, hydrosphere, and biosphere. The total duration of sunshine in Tajikistan ranges from 2100 to 3170 hours per year. Solar collectors can be mounted on the roof of a house after its renovation and modernization. One square meter of surface area in Central Asia accounts for up to 1600 kW/h of solar energy gain, whilst the average gain is 1200 kW/h. Active solar thermal systems are able to collect both low- and high-temperature heat. Active systems require the use of special engineering equipment for the collection, storage, conversion and distribution of heat, while a low-grade system is based on the principle of using a flat solar collector. The collector is connected to the storage tank for storing the heated water, gas, etc. The water temperature is in the range 50-60 °C. For summer air conditioning in hot climates, absorption-based solar installations with open evaporating solution are recommended. The UltraSolar PRO system offers an opportunity to make a home independent of traditional electricity. Combining Schneider Electric power generation and innovative energy storage technology results in an independent power supply. Traditional power supply systems can be short-lived since they store energy in lead-acid batteries which have a negligible lifetime. Lead-acid batteries operate in a constant charge-discharge mode, require specific conditions for best performance and can fail suddenly. Sudden failure of lead acid batteries, especially in winter in the northern part of Tajikistan, completely disables the heating system of a building. Instead, it is recommended to use industrial lithium-ion batteries, which have a significantly longer life and reliability compared to lead-acid type. UltraSolar PRO are ideal and provide a complete package, low noise and compact lithium-ion power supply.

  18. Phytol a Natural Diterpenoid with Pharmacological Applications on Central Nervous System: A Review.

    Science.gov (United States)

    Pereira Costa, Jessica; da Silva Oliveira, Johanssy; Mario Rezende Junior, Luis; de Freitas, Rivelilson Mendes

    2014-01-01

    Phytol (3,7,11,15-tetramethylhexadec-2-en-1-ol), a diterpene member of long and ramified chain of unsaturated acyclic alcohols. The objective of study was to conduct a systematic review of this diterpene and its pharmaceutical applications in Nervous System diseases in humans and/or rodents. Periodicals bases, such as ScienceDirect and PubMed, were used, as well as technological basis of European Patent Office, World Intellectual Property Organization, United States Patent and Trademark Office, Derwent Innovations Index(®), Latin American Bank of Patents and data base of Instituto Nacional de Propriedade Industrial (INPI-National Institute of Industrial Property). The software EndNote-X5 was utilized as reference with the keywords: phytol, anxiolytic, antidepressant and anticonvulsant and their correlations in English, Spanish and Portuguese from January 2003 to June 2014. There are many publications on phytol in international literature. However, there is a reduced number of articles related to pharmacological activities proposed here. In reference to technological bases, patents present a wide range of pharmacological and commercial applications as cosmetics, hypolipodemic, anxiolytic and antidepressant. Therefore, it is necessary to explore phytol molecules, which present high pharmacological potential from scientific and technological points of view, in search of transference of technologies to generate economical and industrial growth.

  19. Electrochemical techniques application in corrosion problems of fossil power plants; Aplicacion de tecnicas electroquimicas en problemas de corrosion en centrales termoelectricas

    Energy Technology Data Exchange (ETDEWEB)

    Cano Castillo, Ulises; Garcia Ochoa, Esteban Miguel; Martinez Villafane, Alberto; Mariaca Rodriguez, Liboria; Malo Tamayo, Jose Maria; Uruchurtu Chavarin, Jorge [Instituto de Investigaciones Electricas, Cuernavaca (Mexico)

    1990-12-31

    Some aspects of the electrochemical techniques employed to evaluate the corrosion at low temperature in fossil power plants are commented, as well as the results obtained with the application of them in three power plants of this type. [Espanol] Se comentan algunos aspectos de tecnicas electroquimicas utilizadas para evaluar la corrosion en baja temperatura en centrales termoelectricas, asi como los resultados de la aplicacion de las mismas en tres centrales de este tipo.

  20. Application of intravenous electrocardiography for insertion of central veins dialysis catheters

    Directory of Open Access Journals (Sweden)

    Beigi Ali

    2009-01-01

    Full Text Available One fifth of the inserted dialysis catheters in the internal jugular or subclavian veins may be misplaced. Appropriate positioning of the catheter tip is sometimes difficult. We attempted to use intravenous electrocardiography (ECG to guide catheter tip positioning in 30 hemodialysis patients (17 (57% were men, and the mean age was 43 ± 12 years. who required vascular accesses for dialysis by insertion of double lumen temporary catheters via the jugular veins. Before cathe-terization, standard ECG on the long lead D II was performed and P-wave height was recorded. P-wave voltage was also measured via the blue (venous and red (arterial lumens, using the guide wire as an electrical conductor. After confirmation of the appropriate position of the catheter tip at the superior vena cava (SVC-right atrial junction using chest radiography, the ECG lead corres-ponding to the right hand was connected to the guide wire lodged inside the lumen of the blue catheter. P-wave height in the long lead D II was recorded. The guide wire was withdrawn so as to bring its tip tangent to the tip of the red catheter. ECG was performed on the long lead D II in a similar manner, and the P-wave height was recorded. The mean P-wave voltage in normal ECG and intravenous ECG (red and blue catheter tips measured 1.27 ± 0.38 mm, 3.10 ± 0.95 mm, and 5.42 ± 1.76 mm, respectively. The difference between the mean P-wave voltages measured in standard and intravenous ECG (blue and red catheter tips was statistically significant (P< 0.05. We conclude that the dialysis catheter tip can be positioned appropriately via the measurement of the P-wave height by intravenous ECG and using the sinoatrial node as an accurate landmark. This method can complement the chest radiography in the appropriate placement of the central vein catheters.

  1. Duke Surgery Research Central: an open-source Web application for the improvement of compliance with research regulation

    Directory of Open Access Journals (Sweden)

    Martins Henrique

    2006-07-01

    Full Text Available Abstract Background Although regulatory compliance in academic research is enforced by law to ensure high quality and safety to participants, its implementation is frequently hindered by cost and logistical barriers. In order to decrease these barriers, we have developed a Web-based application, Duke Surgery Research Central (DSRC, to monitor and streamline the regulatory research process. Results The main objective of DSRC is to streamline regulatory research processes. The application was built using a combination of paper prototyping for system requirements and Java as the primary language for the application, in conjunction with the Model-View-Controller design model. The researcher interface was designed for simplicity so that it could be used by individuals with different computer literacy levels. Analogously, the administrator interface was designed with functionality as its primary goal. DSRC facilitates the exchange of regulatory documents between researchers and research administrators, allowing for tasks to be tracked and documents to be stored in a Web environment accessible from an Intranet. Usability was evaluated using formal usability tests and field observations. Formal usability results demonstrated that DSRC presented good speed, was easy to learn and use, had a functionality that was easily understandable, and a navigation that was intuitive. Additional features implemented upon request by initial users included: extensive variable categorization (in contrast with data capture using free text, searching capabilities to improve how research administrators could search an extensive number of researcher names, warning messages before critical tasks were performed (such as deleting a task, and confirmatory e-mails for critical tasks (such as completing a regulatory task. Conclusion The current version of DSRC was shown to have excellent overall usability properties in handling research regulatory issues. It is hoped that its

  2. Modeling vadose zone processes during land application of food-processing waste water in California's Central Valley.

    Science.gov (United States)

    Miller, Gretchen R; Rubin, Yoram; Mayer, K Ulrich; Benito, Pascual H

    2008-01-01

    Land application of food-processing waste water occurs throughout California's Central Valley and may be degrading local ground water quality, primarily by increasing salinity and nitrogen levels. Natural attenuation is considered a treatment strategy for the waste, which often contains elevated levels of easily degradable organic carbon. Several key biogeochemical processes in the vadose zone alter the characteristics of the waste water before it reaches the ground water table, including microbial degradation, crop nutrient uptake, mineral precipitation, and ion exchange. This study used a process-based, multi-component reactive flow and transport model (MIN3P) to numerically simulate waste water migration in the vadose zone and to estimate its attenuation capacity. To address the high variability in site conditions and waste-stream characteristics, four food-processing industries were coupled with three site scenarios to simulate a range of land application outcomes. The simulations estimated that typically between 30 and 150% of the salt loading to the land surface reaches the ground water, resulting in dissolved solids concentrations up to sixteen times larger than the 500 mg L(-1) water quality objective. Site conditions, namely the ratio of hydraulic conductivity to the application rate, strongly influenced the amount of nitrate reaching the ground water, which ranged from zero to nine times the total loading applied. Rock-water interaction and nitrification explain salt and nitrate concentrations that exceed the levels present in the waste water. While source control remains the only method to prevent ground water degradation from saline wastes, proper site selection and waste application methods can reduce the risk of ground water degradation from nitrogen compounds.

  3. Nonradioactive Air Emissions Notice of Construction (NOC) Application for the Central Waste Complex (CSC) for Storage of Vented Waste Containers

    Energy Technology Data Exchange (ETDEWEB)

    KAMBERG, L.D.

    2000-04-01

    This Notice of Construction (NOC) application is submitted for the storage and management of waste containers at the Central Waste Complex (CWC) stationary source. The CWC stationary source consists of multiple sources of diffuse and fugitive emissions, as described herein. This NOC is submitted in accordance with the requirements of Washington Administrative Code (WAC) 173-400-110 (criteria pollutants) and 173-460-040 (toxic air pollutants), and pursuant to guidance provided by the Washington State Department of Ecology (Ecology). Transuranic (TRU) mixed waste containers at CWC are vented to preclude the build up of hydrogen produced as a result of radionuclide decay, not as safety pressure releases. The following activities are conducted within the CWC stationary source: Storage and inspection; Transfer and staging; Packaging; Treatment; and Sampling. This NOC application is intended to cover all existing storage structures within the current CWC treatment, storage, and/or disposal (TSD) boundary, as well as any storage structures, including waste storage pads and staging areas, that might be constructed in the future within the existing CWC boundary.

  4. Identification of a nutrient-sensing transcriptional network in monocytes by using inbred rat models on a cafeteria diet.

    Science.gov (United States)

    Martínez-Micaelo, Neus; González-Abuín, Noemi; Terra, Ximena; Ardévol, Ana; Pinent, Montserrat; Petretto, Enrico; Behmoaras, Jacques; Blay, Mayte

    2016-10-01

    Obesity has reached pandemic levels worldwide. The current models of diet-induced obesity in rodents use predominantly high-fat based diets that do not take into account the consumption of variety of highly palatable, energy-dense foods that are prevalent in Western society. We and others have shown that the cafeteria (CAF) diet is a robust and reproducible model of human metabolic syndrome with tissue inflammation in the rat. We have previously shown that inbred rat strains such as Wistar Kyoto (WKY) and Lewis (LEW) show different susceptibilities to CAF diets with distinct metabolic and morphometric profiles. Here, we show a difference in plasma MCP-1 levels and investigate the effect of the CAF diet on peripheral blood monocyte transcriptome, as powerful stress-sensing immune cells, in WKY and LEW rats. We found that 75.5% of the differentially expressed transcripts under the CAF diet were upregulated in WKY rats and were functionally related to the activation of the immune response. Using a gene co-expression network constructed from the genes differentially expressed between CAF diet-fed LEW and WKY rats, we identified acyl-CoA synthetase short-chain family member 2 (Acss2) as a hub gene for a nutrient-sensing cluster of transcripts in monocytes. The Acss2 genomic region is significantly enriched for previously established metabolism quantitative trait loci in the rat. Notably, monocyte expression levels of Acss2 significantly correlated with plasma glucose, triglyceride, leptin and non-esterified fatty acid (NEFA) levels as well as morphometric measurements such as body weight and the total fat following feeding with the CAF diet in the rat. These results show the importance of the genetic background in nutritional genomics and identify inbred rat strains as potential models for CAF-diet-induced obesity.

  5. Cafeteria diet and probiotic therapy: cross talk among memory, neuroplasticity, serotonin receptors and gut microbiota in the rat.

    Science.gov (United States)

    Beilharz, J E; Kaakoush, N O; Maniam, J; Morris, M J

    2017-03-14

    The western diet is known to have detrimental effects on cognition and the gut microbiota, but few studies have investigated how these may be related. Here, we examined whether a probiotic could prevent diet-induced memory deficits. Rats were pre-exposed to vehicle, low or high doses of VSL#3 for 2 weeks before half were switched from chow to a cafeteria diet (Caf) for 25 days; VSL#3 treatment continued until death. High-dose VSL#3 prevented the diet-induced memory deficits on the hippocampal-dependent place task, but the probiotic caused deficits on the perirhinal-dependent object task, irrespective of diet or dose. No differences were observed in anxiety-like behaviour on the elevated plus maze. Gut microbial diversity was dramatically decreased by Caf diet and here, VSL#3 was able to increase the abundance of some taxa contained in the probiotic such as Streptococcus and Lactobacillus and also other taxa including Butyrivibrio, which were decreased by the Caf diet. This affected the predicted profile of microbial metabolic pathways related to antioxidant and bile biosynthesis, and fat and carbohydrate metabolism. In the hippocampus, the Caf diet increased the expression of many genes related to neuroplasticity and serotonin receptor (5HT) 1A, which was normalised in Caf-High rats. Distance-based linear modelling showed that these genes were the best predictors of place memory, and related to microbiota principal component (PC) 1. Neuroplasticity genes in the perirhinal cortex were also affected and related to PC1 but object memory performance was correlated with perirhinal 5HT2C expression and microbiota PC3. These results show that probiotics can be beneficial in situations of gut dysbiosis where memory deficits are evident but may be detrimental in healthy subjects.Molecular Psychiatry advance online publication, 14 March 2017; doi:10.1038/mp.2017.38.

  6. Identification of a nutrient-sensing transcriptional network in monocytes by using inbred rat models on a cafeteria diet

    Science.gov (United States)

    Martínez-Micaelo, Neus; González-Abuín, Noemi; Terra, Ximena; Ardévol, Ana; Pinent, Montserrat; Petretto, Enrico; Blay, Mayte

    2016-01-01

    ABSTRACT Obesity has reached pandemic levels worldwide. The current models of diet-induced obesity in rodents use predominantly high-fat based diets that do not take into account the consumption of variety of highly palatable, energy-dense foods that are prevalent in Western society. We and others have shown that the cafeteria (CAF) diet is a robust and reproducible model of human metabolic syndrome with tissue inflammation in the rat. We have previously shown that inbred rat strains such as Wistar Kyoto (WKY) and Lewis (LEW) show different susceptibilities to CAF diets with distinct metabolic and morphometric profiles. Here, we show a difference in plasma MCP-1 levels and investigate the effect of the CAF diet on peripheral blood monocyte transcriptome, as powerful stress-sensing immune cells, in WKY and LEW rats. We found that 75.5% of the differentially expressed transcripts under the CAF diet were upregulated in WKY rats and were functionally related to the activation of the immune response. Using a gene co-expression network constructed from the genes differentially expressed between CAF diet-fed LEW and WKY rats, we identified acyl-CoA synthetase short-chain family member 2 (Acss2) as a hub gene for a nutrient-sensing cluster of transcripts in monocytes. The Acss2 genomic region is significantly enriched for previously established metabolism quantitative trait loci in the rat. Notably, monocyte expression levels of Acss2 significantly correlated with plasma glucose, triglyceride, leptin and non-esterified fatty acid (NEFA) levels as well as morphometric measurements such as body weight and the total fat following feeding with the CAF diet in the rat. These results show the importance of the genetic background in nutritional genomics and identify inbred rat strains as potential models for CAF-diet-induced obesity. PMID:27483348

  7. Recognition of central sensitization in patients with musculoskeletal pain: Application of pain neurophysiology in manual therapy practice.

    NARCIS (Netherlands)

    Nijs, J.; Houdenhove, B. Van; Oostendorp, R.A.B.

    2010-01-01

    Central sensitization plays an important role in the pathophysiology of numerous musculoskeletal pain disorders, yet it remains unclear how manual therapists can recognize this condition. Therefore, mechanism based clinical guidelines for the recognition of central sensitization in patients with mus

  8. Hanford facility dangerous waste Part A, Form 3 and Part B permit application documentation, Central Waste Complex (WA7890008967)(TSD: TS-2-4)

    Energy Technology Data Exchange (ETDEWEB)

    Saueressig, D.G.

    1998-05-20

    The Hanford Facility Dangerous Waste Permit Application is considered to be a single application organized into a General Information Portion (document number DOE/RL-91-28) and a Unit-Specific Portion. The scope of the Unit-Specific Portion is limited to Part B permit application documentation submitted for individual, operating, treatment, storage, and/or disposal units, such as the Central Waste Complex (this document, DOE/RL-91-17). Both the General Information and Unit-Specific portions of the Hanford Facility Dangerous Waste Permit Application address the content of the Part B permit application guidance prepared by the Washington State Department of Ecology (Ecology 1996) and the U.S. Environmental Protection Agency (40 Code of Federal Regulations 270), with additional information needed by the Hazardous and Solid Waste Amendments and revisions of Washington Administrative Code 173-303. For ease of reference, the Washington State Department of Ecology alpha-numeric section identifiers from the permit application guidance documentation (Ecology 1996) follow, in brackets, the chapter headings and subheadings. A checklist indicating where information is contained in the Central Waste Complex permit application documentation, in relation to the Washington State Department of Ecology guidance, is located in the Contents section. Documentation contained in the General Information Portion is broader in nature and could be used by multiple treatment, storage, and/or disposal units (e.g., the glossary provided in the General Information Portion). Wherever appropriate, the Central Waste Complex permit application documentation makes cross-reference to the General Information Portion, rather than duplicating text. Information provided in this Central Waste Complex permit application documentation is current as of May 1998.

  9. Cafeteria diet induces obesity and insulin resistance associated with oxidative stress but not with inflammation: improvement by dietary supplementation with a melon superoxide dismutase.

    Science.gov (United States)

    Carillon, Julie; Romain, Cindy; Bardy, Guillaume; Fouret, Gilles; Feillet-Coudray, Christine; Gaillet, Sylvie; Lacan, Dominique; Cristol, Jean-Paul; Rouanet, Jean-Max

    2013-12-01

    Oxidative stress is involved in obesity. However, dietary antioxidants could prevent oxidative stress-induced damage. We have previously shown the preventive effects of a melon superoxide dismutase (SODB) on oxidative stress. However, the mechanism of action of SODB is still unknown. Here, we evaluated the effects of a 1-month curative supplementation with SODB on the liver of obese hamsters. Golden Syrian hamsters received either a standard diet or a cafeteria diet composed of high-fat, high-sugar, and high-salt supermarket products, for 15 weeks. This diet resulted in insulin resistance and in increased oxidative stress in the liver. However, inflammatory markers (IL-6, TNF-α, and NF-κB) were not enhanced and no liver steatosis was detected, although these are usually described in obesity-induced insulin resistance models. After the 1-month supplementation with SODB, body weight and insulin resistance induced by the cafeteria diet were reduced and hepatic oxidative stress was corrected. This could be due to the increased expression of the liver antioxidant defense proteins (manganese and copper/zinc superoxide dismutase, catalase, and glutathione peroxidase). Even though no inflammation was detected in the obese hamsters, inflammatory markers were decreased after SODB supplementation, probably through the reduction of oxidative stress. These findings suggest for the first time that SODB could exert its antioxidant properties by inducing the endogenous antioxidant defense. The mechanisms underlying this induction need to be further investigated.

  10. Synthesis of fluorine substituted hydroxyapatite nanopowders and application of the central composite design for determination of its antimicrobial effects

    Science.gov (United States)

    Stanić, Vojislav; Dimitrijević, Suzana; Antonović, Dušan G.; Jokić, Bojan M.; Zec, Slavica P.; Tanasković, Sladjana T.; Raičević, Slavica

    2014-01-01

    Synthetic biomaterials based on fluorine substituted hydroxyapatite are potentially attractive for orthopedic and dental implant applications. The new synthesis of fluorine substituted hydroxyapatite samples were done by neutralization, which consists of adding the solution of HF and H3PO4 in suspension of Ca(OH)2. Characterization studies from XRD, SEM and FTIR spectra showed that crystals are obtained with apatite structure and those particles of all samples are nano size, with an average length of 80 nm and about 15-25 nm in diameter. The central composite design was used in order to determine the optimal conditions for the antimicrobial activity of the synthesized samples. In order to evaluate the influence of operating parameters on the percent of viable cell reduction of Streptococcus mutans, three independent variables were chosen: exposure time, pH of saline and floride concentration in apatite samples. The experimental and predicted antimicrobial activities were in close agreement. Antimicrobial activity of the samples increases with the increase of fluoride concentration and the decreased pH of saline. The maximum antimicrobial activity was achieved at the initial pH of 4.

  11. Investigation on Fuzzy Logic Based Centralized Control in Four-Port SEPIC/ZETA Bidirectional Converter for Photovoltaic Applications

    Directory of Open Access Journals (Sweden)

    VENMATHI, M.

    2016-02-01

    Full Text Available In this paper, a new four-port DC-DC converter topology is proposed to interface renewable energy sources and the load along with the energy storage device. The proposed four-port SEPIC/ZETA bidirectional converter (FP-SEPIC/ZETA BDC converter comprises an isolated output port with two unidirectional and one bidirectional input ports. This converter topology is obtained by the fusion of SEPIC/ZETA BDC and full-bridge converter. This converter topology ensures the non-reversal of output voltage hence it is preferred mostly for battery charging applications. In this work, photovoltaic (PV source is considered and the power balance in the system is achieved by means of distributed maximum power point tracking (DMPPT in the PV ports. The centralized controller is implemented using fuzzy logic controller (FLC and the performance is compared with conventional proportional integral (PI controller. The results offer useful information to obtain the desired output under line and load regulations. Experimental results are also provided to validate the simulation results.

  12. Treadmill Intervention Attenuates the Cafeteria Diet-Induced Impairment of Stress-Coping Strategies in Young Adult Female Rats

    Science.gov (United States)

    Cigarroa, Igor; Lalanza, Jaume F.; Caimari, Antoni; del Bas, Josep M.; Capdevila, Lluís; Arola, Lluís; Escorihuela, Rosa M.

    2016-01-01

    The current prevalence of diet-induced overweight and obesity in adolescents and adults is continuously growing. Although the detrimental biochemical and metabolic consequences of obesity are widely studied, its impact on stress-coping behavior and its interaction with specific exercise doses (in terms of intensity, duration and frequency) need further investigation. To this aim, we fed adolescent rats either an obesogenic diet (cafeteria diet, CAF) or standard chow (ST). Each group was subdivided into four subgroups according to the type of treadmill intervention as follows: a sedentary group receiving no manipulation; a control group exposed to a stationary treadmill; a low-intensity treadmill group trained at 12 m/min; and a higher intensity treadmill group trained at 17 m/min. Both the diet and treadmill interventions started at weaning and lasted for 8 weeks. Subjects were tested for anxiety-like behavior in the open field test and for coping strategies in the two-way active avoidance paradigm at week 7 and were sacrificed at week 8 for biometric and metabolic characterization. CAF feeding increased the weight gain, relative retroperitoneal white adipose tissue (RWAT %), and plasma levels of glucose, insulin, triglycerides and leptin and decreased the insulin sensitivity. Treadmill intervention partially reversed the RWAT% and triglyceride alterations; at higher intensity, it decreased the leptin levels of CAF-fed animals. CAF feeding decreased the motor activity and impaired the performance in a two-way active avoidance assessment. Treadmill intervention reduced defecation in the shuttle box, suggesting diminished anxiety. CAF feeding combined with treadmill training at 17 m/min increased the time spent in the center of the open field and more importantly, partially reversed the two-way active avoidance deficit. In conclusion, this study demonstrates that at doses that decreased anxiety-like behavior, treadmill exercise partially improved the coping strategy

  13. The application values of cerebrospinal fluid cytological examination by slide centrifugation for diagnosis of central nervous system infectious diseases

    Directory of Open Access Journals (Sweden)

    LIU Ting-ting

    2013-02-01

    Full Text Available According to the analysis of cerebrospnial fluid (CSF cytological examination (by slide centrifugation results of 15 940 central nervous system infectious cases, this cytologic examination method shows definite diagnostic values as follows: 1 better etiological diagnostic value for central nervous system infectious diseases, such as purulent, viral, tuberculous, fungus and parasitic encephalitis meningitis and meningoencephalitis; 2 better differential diagnostic value for acute infectious toxic encephalopathy, meningeal carcinomatosis and central nervous system non-infectious diseases such as tumorous, leukemic and hemorrhagic meningoencephalitis and encephalopathy; 3 better clinical value for severity monitoring and prognostic judgement of central nervous system infectious diseases.

  14. Simple interventions to improve healthy eating behaviors in the school cafeteria

    Science.gov (United States)

    2016-01-01

    The National School Lunch Program in the United States provides an important opportunity to improve nutrition for the 30 million children who participate every school day. The purpose of this narrative review is to present and evaluate simple, evidence-based strategies to improve healthy eating behaviors at school. Healthy eating behaviors are defined as increased selection/consumption of fruits and/or vegetables, increased selection of nutrient-dense foods, or decreased selection of low-nutrient, energy-dense foods. Data were collected from sales records, 24-hour food recalls, direct observation, and estimation of plate waste. The review is limited to simple, discrete interventions that are easy to implement. Sixteen original, peer-reviewed articles are included. Interventions are divided into 5 categories: modification of choice, behavior modification, marketing strategies, time-efficiency strategies, and fruit slicing. All interventions resulted in improved eating behaviors, but not all interventions are applicable or feasible in all settings. Because these studies were performed prior to the implementation of the new federally mandated school meal standards, it is unknown if these interventions would yield similar results if repeated now. PMID:26874753

  15. Simple interventions to improve healthy eating behaviors in the school cafeteria.

    Science.gov (United States)

    Kessler, Holly S

    2016-03-01

    The National School Lunch Program in the United States provides an important opportunity to improve nutrition for the 30 million children who participate every school day. The purpose of this narrative review is to present and evaluate simple, evidence-based strategies to improve healthy eating behaviors at school. Healthy eating behaviors are defined as increased selection/consumption of fruits and/or vegetables, increased selection of nutrient-dense foods, or decreased selection of low-nutrient, energy-dense foods. Data were collected from sales records, 24-hour food recalls, direct observation, and estimation of plate waste. The review is limited to simple, discrete interventions that are easy to implement. Sixteen original, peer-reviewed articles are included. Interventions are divided into 5 categories: modification of choice, behavior modification, marketing strategies, time-efficiency strategies, and fruit slicing. All interventions resulted in improved eating behaviors, but not all interventions are applicable or feasible in all settings. Because these studies were performed prior to the implementation of the new federally mandated school meal standards, it is unknown if these interventions would yield similar results if repeated now.

  16. Applications of fluorescence spectroscopy to problems of food safety: detection of fecal contamination and of the presence of central nervous system tissue and diagnosis of neurological disease

    Science.gov (United States)

    Adhikary, Ramkrishna; Bose, Sayantan; Casey, Thomas A.; Gapsch, Al; Rasmussen, Mark A.; Petrich, Jacob W.

    2010-02-01

    Applications of fluorescence spectroscopy that enable the real-time or rapid detection of fecal contamination on beef carcasses and the presence of central nervous system tissue in meat products are discussed. The former is achieved by employing spectroscopic signatures of chlorophyll metabolites; the latter, by exploiting the characteristic structure and intensity of lipofuscin in central nervous system tissue. The success of these techniques has led us to investigate the possibility of diagnosing scrapie in sheep by obtaining fluorescence spectra of the retina. Crucial to this diagnosis is the ability to obtain baseline correlations of lipofuscin fluorescence with age. A murine model was employed as a proof of principle of this correlation.

  17. Criteria for Selecting and Adjusting Ground-Motion Models for Specific Target Regions: Application to Central Europe and Rock Sites

    Science.gov (United States)

    Cotton, Fabrice; Scherbaum, Frank; Bommer, Julian J.; Bungum, Hilmar

    2006-04-01

    A vital component of any seismic hazard analysis is a model for predicting the expected distribution of ground motions at a site due to possible earthquake scenarios. The limited nature of the datasets from which such models are derived gives rise to epistemic uncertainty in both the median estimates and the associated aleatory variability of these predictive equations. In order to capture this epistemic uncertainty in a seismic hazard analysis, more than one ground-motion prediction equation must be used, and the tool that is currently employed to combine multiple models is the logic tree. Candidate ground-motion models for a logic tree should be selected in order to obtain the smallest possible suite of equations that can capture the expected range of possible ground motions in the target region. This is achieved by starting from a comprehensive list of available equations and then applying criteria for rejecting those considered inappropriate in terms of quality, derivation or applicability. Once the final list of candidate models is established, adjustments must be applied to achieve parameter compatibility. Additional adjustments can also be applied to remove the effect of systematic differences between host and target regions. These procedures are applied to select and adjust ground-motion models for the analysis of seismic hazard at rock sites in West Central Europe. This region is chosen for illustrative purposes particularly because it highlights the issue of using ground-motion models derived from small magnitude earthquakes in the analysis of hazard due to much larger events. Some of the pitfalls of extrapolating ground-motion models from small to large magnitude earthquakes in low seismicity regions are discussed for the selected target region.

  18. Application of a process-based shallow landslide hazard model over a broad area in Central Italy

    Science.gov (United States)

    Gioia, Eleonora; Speranza, Gabriella; Ferretti, Maurizio; Godt, Jonathan W.; Baum, Rex L.; Marincioni, Fausto

    2015-01-01

    Process-based models are widely used for rainfall-induced shallow landslide forecasting. Previous studies have successfully applied the U.S. Geological Survey’s Transient Rainfall Infiltration and Grid-Based Regional Slope-Stability (TRIGRS) model (Baum et al. 2002) to compute infiltration-driven changes in the hillslopes’ factor of safety on small scales (i.e., tens of square kilometers). Soil data input for such models are difficult to obtain across larger regions. This work describes a novel methodology for the application of TRIGRS over broad areas with relatively uniform hydrogeological properties. The study area is a 550-km2 region in Central Italy covered by post-orogenic Quaternary sediments. Due to the lack of field data, we assigned mechanical and hydrological property values through a statistical analysis based on literature review of soils matching the local lithologies. We calibrated the model using rainfall data from 25 historical rainfall events that triggered landslides. We compared the variation of pressure head and factor of safety with the landslide occurrence to identify the best fitting input conditions. Using calibrated inputs and a soil depth model, we ran TRIGRS for the study area. Receiver operating characteristic (ROC) analysis, comparing the model’s output with a shallow landslide inventory, shows that TRIGRS effectively simulated the instability conditions in the post-orogenic complex during historical rainfall scenarios. The implication of this work is that rainfall-induced landslides over large regions may be predicted by a deterministic model, even where data on geotechnical and hydraulic properties as well as temporal changes in topography or subsurface conditions are not available.

  19. Application of a Central Composite Design for the Study of NOx Emission Performance of a Low NOx Burner

    Directory of Open Access Journals (Sweden)

    Marcin Dutka

    2015-04-01

    Full Text Available In this study, the influence of various factors on nitrogen oxides (NOx emissions of a low NOx burner is investigated using a central composite design (CCD approach to an experimental matrix in order to show the applicability of design of experiments methodology to the combustion field. Four factors have been analyzed in terms of their impact on NOx formation: hydrogen fraction in the fuel (0%–15% mass fraction in hydrogen-enriched methane, amount of excess air (5%–30%, burner head position (20–25 mm from the burner throat and secondary fuel fraction provided to the burner (0%–6%. The measurements were performed at a constant thermal load equal to 25 kW (calculated based on lower heating value. Response surface methodology and CCD were used to develop a second-degree polynomial regression model of the burner NOx emissions. The significance of the tested factors over their respective ranges has been evaluated using the analysis of variance and by the consideration of the coefficients of the model equation. Results show that hydrogen addition to methane leads to increased NOx emissions in comparison to emissions from pure methane combustion. Hydrogen content in a fuel is the strongest factor affecting NOx emissions among all the factors tested. Lower NOx formation because of increased excess air was observed when the burner was fuelled by pure methane, but this effect diminished for hydrogen-rich fuel mixtures. NOx emissions were slightly reduced when the burner head was shifted closer to the burner outer tube, whereas a secondary fuel stream provided to the burner was found to have no impact on NOx emissions over the investigated range of factors.

  20. Application of the 2012 revised diagnostic definitions for paediatric multiple sclerosis and immune-mediated central nervous system demyelination disorders

    NARCIS (Netherlands)

    van Pelt, E. Danielle; Neuteboom, Rinze F.; Ketelslegers, Immy A.; Boon, Maartje; Catsman-Berrevoets, Coriene E.; Hintzen, Rogier Q.

    2014-01-01

    Background Recently, the International Paediatric Multiple Sclerosis Study Group (IPMSSG) definitions for the diagnosis of immune-mediated acquired demyelinating syndromes (ADS) of the central nervous system, including paediatric multiple sclerosis (MS), have been revised. Objective To evaluate the

  1. Floor vibration test and analysis of a school cafeteria%某学校食堂楼板振动测试及分析

    Institute of Scientific and Technical Information of China (English)

    樊振华

    2011-01-01

    This paper made vibration test according to a school boiler room heat exchanger operation induced the adjacent cafeteria frame structure each floor vibration situations,analyzed the vibration causes,and put forward the corresponding countermeasures,thus eliminated the vibration phenomenons,accumulated some experience for the future similar projects.%针对某学校锅炉房冷热交换器运行引起邻近食堂框架结构各层楼板振动的情况进行了振动测试,分析了振动原因,并提出了相应的对策,从而消除了结构振动现象,为今后同类工程积累了一定经验。

  2. The saponin-rich fraction of a Gymnema sylvestre R. Br. aqueous leaf extract reduces cafeteria and high-fat diet-induced obesity.

    Science.gov (United States)

    Reddy, Rama Manohar I; Latha, Pushpa B; Vijaya, Tartte; Rao, Dattatreya S

    2012-01-01

    We examined the antiobesity effect of a saponin-rich fraction of a Gymnema sylvestre R. Br. aqueous leaf extract (SGE) using cafeteria and high-fat diet-induced obese rats for a period of eight weeks. SGE was orally administered at a dose of 100 mg/kg body weight once a day to the treatment group. It significantly decreased the body weight, food consumption, visceral organs weight, and the levels of triglycerides, total cholesterol, low-density lipoproteins, very low-density lipoproteins, atherogenic index, glucose, and increased the levels of high-density lipoproteins. There was no significant difference with respect to all parameters of the study in case of normal (N) diet and N diet + SGE rats. In vitro, SGE inhibited the pancreatic lipase activity. The present study gave clear evidence that the SGE has a significant antiobese action, supporting its use in traditional medicine, and can be used as a substitute for synthetic drugs.

  3. Effects Of A Post-Weaning Cafeteria Diet In Young Rats: Metabolic Syndrome, Reduced Activity And Low Anxiety-Like Behaviour

    Science.gov (United States)

    Lalanza, Jaume F.; Caimari, Antoni; del Bas, Josep M.; Torregrosa, Daniel; Cigarroa, Igor; Pallàs, Mercè; Capdevila, Lluís; Arola, Lluís; Escorihuela, Rosa M.

    2014-01-01

    Among adolescents, overweight, obesity and metabolic syndrome are rapidly increasing in recent years as a consequence of unhealthy palatable diets. Animal models of diet-induced obesity have been developed, but little is known about the behavioural patterns produced by the consumption of such diets. The aim of the present study was to determine the behavioural and biochemical effects of a cafeteria diet fed to juvenile male and female rats, as well as to evaluate the possible recovery from these effects by administering standard feeding during the last week of the study. Two groups of male and female rats were fed with either a standard chow diet (ST) or a cafeteria (CAF) diet from weaning and for 8 weeks. A third group of males (CAF withdrawal) was fed with the CAF diet for 7 weeks and the ST in the 8th week. Both males and females developed metabolic syndrome as a consequence of the CAF feeding, showing overweight, higher adiposity and liver weight, increased plasma levels of glucose, insulin and triglycerides, as well as insulin resistance, in comparison with their respective controls. The CAF diet reduced motor activity in all behavioural tests, enhanced exploration, reduced anxiety-like behaviour and increased social interaction; this last effect was more pronounced in females than in males. When compared to animals only fed with a CAF diet, CAF withdrawal increased anxiety in the open field, slightly decreased body weight, and completely recovered the liver weight, insulin sensitivity and the standard levels of glucose, insulin and triglycerides in plasma. In conclusion, a CAF diet fed to young animals for 8 weeks induced obesity and metabolic syndrome, and produced robust behavioural changes in young adult rats, whereas CAF withdrawal in the last week modestly increased anxiety, reversed the metabolic alterations and partially reduced overweight. PMID:24482678

  4. Inflamação renal, alterações metabólicas e oxidativas após 6 semanas de dieta de cafeteria em ratos

    Directory of Open Access Journals (Sweden)

    Maria Eugênia Lopes Navarro

    2016-03-01

    Full Text Available Resumo Introdução: A obesidade é uma doença em que a inflamação está inteiramente envolvida e pode causar insuficiência renal. Objetivo: Avaliar a influência da exposição a curto prazo de uma dieta de cafeteria sobre a inflamação no tecido renal e a formação de produtos de glicação avançada (AGEs no plasma de rato. Métodos: Ratos Wistar machos (10 semanas de idade, pesando 350 g foram designados para receber dieta de ração comercial (C; n = 8 animais/grupo, 5% de energia a partir de gordura ou dieta de cafeteria (CAF-D, n = 8 animais/grupo: 29% de energia de gordura e de sacarose em água (300 g/L de beber durante 6 semanas. Resultados: Índice de adiposidade em seis semanas foi maior no grupo CAF-D em comparação com C. O mesmo comportamento foi observado para os níveis plasmáticos de glicose, triglicerídeos, leptina, insulina e AGEs. A expressão do gene de IL-6 e TNF-α em tecido renal foi maior no grupo D-CAF e nenhuma diferença significativa no tecido adiposo. Não houve aumento destas citocinas no plasma ou rim. Houve uma diminuição significativa de adiponectina no grupo CAF-D. Conclusão: A exposição a curto prazo da CAF-D reflete alterações no metabolismo, aumento dos níveis plasmáticos de AGEs, o que pode refletir o aumento expressão de citocinas inflamatórias no rim.

  5. Effects of a post-weaning cafeteria diet in young rats: metabolic syndrome, reduced activity and low anxiety-like behaviour.

    Science.gov (United States)

    Lalanza, Jaume F; Caimari, Antoni; del Bas, Josep M; Torregrosa, Daniel; Cigarroa, Igor; Pallàs, Mercè; Capdevila, Lluís; Arola, Lluís; Escorihuela, Rosa M

    2014-01-01

    Among adolescents, overweight, obesity and metabolic syndrome are rapidly increasing in recent years as a consequence of unhealthy palatable diets. Animal models of diet-induced obesity have been developed, but little is known about the behavioural patterns produced by the consumption of such diets. The aim of the present study was to determine the behavioural and biochemical effects of a cafeteria diet fed to juvenile male and female rats, as well as to evaluate the possible recovery from these effects by administering standard feeding during the last week of the study. Two groups of male and female rats were fed with either a standard chow diet (ST) or a cafeteria (CAF) diet from weaning and for 8 weeks. A third group of males (CAF withdrawal) was fed with the CAF diet for 7 weeks and the ST in the 8th week. Both males and females developed metabolic syndrome as a consequence of the CAF feeding, showing overweight, higher adiposity and liver weight, increased plasma levels of glucose, insulin and triglycerides, as well as insulin resistance, in comparison with their respective controls. The CAF diet reduced motor activity in all behavioural tests, enhanced exploration, reduced anxiety-like behaviour and increased social interaction; this last effect was more pronounced in females than in males. When compared to animals only fed with a CAF diet, CAF withdrawal increased anxiety in the open field, slightly decreased body weight, and completely recovered the liver weight, insulin sensitivity and the standard levels of glucose, insulin and triglycerides in plasma. In conclusion, a CAF diet fed to young animals for 8 weeks induced obesity and metabolic syndrome, and produced robust behavioural changes in young adult rats, whereas CAF withdrawal in the last week modestly increased anxiety, reversed the metabolic alterations and partially reduced overweight.

  6. The cafeteria terrace

    CERN Multimedia

    1987-01-01

    The large terrace area outside Restaurant 1 at CERN is a hive of activity in the summer. Visitors and staff members meet here for breaks from work. Often the air is filled with discussion in many different accents and languages on topics from theoretical physics to the weekend's activities.

  7. SU-E-E-16: The Application of Texture Analysis for Differentiation of Central Cancer From Atelectasis

    Energy Technology Data Exchange (ETDEWEB)

    Gao, M; Fan, T; Duan, J [Shandong Tumor Hospital, Jinan, Shandong province (China)

    2015-06-15

    Purpose: Prospectively assess the potential utility of texture analysis for differentiation of central cancer from atelectasis. Methods: 0 consecutive central lung cancer patients who were referred for CT imaging and PET-CT were enrolled. Radiotherapy doctor delineate the tumor and atelectasis according to the fusion imaging based on CT image and PET-CT image. The texture parameters (such as energy, correlation, sum average, difference average, difference entropy), were obtained respectively to quantitatively discriminate tumor and atelectasis based on gray level co-occurrence matrix (GLCM) Results: The texture analysis results showed that the parameters of correlation and sum average had an obviously statistical significance(P<0.05). Conclusion: the results of this study indicate that texture analysis may be useful for the differentiation of central lung cancer and atelectasis.

  8. Sunkist. Edificio Central – (EE. UU.

    Directory of Open Access Journals (Sweden)

    Albert C. Martin, Asociados

    1972-04-01

    Full Text Available Sunkist central building – (U.S.A. Architects: Albert C. Martin and Associates It consists of three floors: — the ground floor includes an auditorium, kitchen and cafeteria, a private diningroom, office area, etc.; — on the first floor are the sales department and the electronic data processing department, and — on the second floor, the firm's executive personnel department, and three kitchens for experimenting with products and developing formulas. This building was planned with the idea of reviving, by the design and the materials used, the memory and character of Old California.Consta de tres plantas: — la baja comprende: un auditorio, cocina y cafetería; un comedor privado, una zona dedicada a oficinas, etc.; — la segunda planta contiene: los departamentos de ventas y de proceso electrónico de datos, y — en la tercera planta se distribuyen: el departamento de personal ejecutivo de la empresa; y tres cocinas para la experimentación de productos y de fórmulas a desarrollar. El edificio fue proyectado pensando en que, por sus materiales y diseño, suscitase el recuerdo y el carácter de la antigua California.

  9. Research and application of hydraulic centralizer for horizontal well cementing%水平井固井液压扶正器的研究与应用

    Institute of Scientific and Technical Information of China (English)

    徐鑫; 魏新芳; 王书峰

    2012-01-01

    Casing tends to be put near the lower wellbore when cementing horizontal wells, in other words, the centralized degree is poor, so the cement thickness is unequal around the casing, resulting in poor cementing quality, and it restricts the advantages of horizontal wells severely. Centralizer is usually used to improve the casing centralized degree in the field, but conventional centralizers has some problems, such as large diameter, difficulties in tripping into the hole, and breaking wellbore. So the hydraulic centralizer for horizontal well cementing was developed. It has some advantages, such as small original diameter, safety in tripping into the hole and large diameter after expansion. It can improve the centralized degree significantly and make burbling effect in cementing. The quality of cementing is improved greatly with the hydraulic centralizer. The application of centralizer in fields is simple, and does not affect cementing process. The tool has been used in many wells in Shengli Oilfield with significant effect%水平井固井时套管往往偏向下井壁,居中度差,固井后形成的水泥环薄厚不均,导致水平井固井质量差,严重制约了水平井优势的发挥.现场多使用扶正器来提高套管居中度,但是常规扶正器存在外径大、下入困难、破坏井壁的问题,为此专门研制开发了水平井固井液压扶正器.该工具原始外径小、下入安全,膨胀后外径大、扶正能力强,能够显著提高水平井套管的居中度,扶正器上的扶正片能够对固井水泥浆产生扰流作用,大大提高了水平井的固井质量.该类扶正器现场应用简便,不影响正常的施工程序,在胜利油田进行了多口井的现场应用,效果显著.

  10. Application of HBS in multi-connected central air conditioning%HBS在多联中央空调中的应用

    Institute of Scientific and Technical Information of China (English)

    何惠湘

    2016-01-01

    HBS with its high reliability, easy wiring and other advantages is widely used in multi-connected central air conditioning products. In this paper, the HBS driver chip MM1192 and its communication circuit design and working process analysis are introduced in detail, and the application of the HBS protocol in the multi-connnected of the central air conditioning product controller is discussed.%HBS以其高可靠性、接线方便等优点被广泛应用在多联中央空调产品中。文章详细介绍了HBS驱动芯片MM1192及与之相连的通信电路的设计及工作过程分析,对多联中央空调产品控制器HBS协议的应用进行了探讨。

  11. 高校餐厅声环境质量分析及防治对策%Analysis and Control Measures of Sound Environment Quality About the University Cafeteria

    Institute of Scientific and Technical Information of China (English)

    王振艳

    2012-01-01

    The university cafeteria is the mainly frequent location of eating and conversation for teachers and students, therefore, it is essential to improve their physical and mental health by studying the sound quality of the university cafeteria. In the paper, Sound environment quality of university cafeteria is analyzed and evaluated by means of site monitoring. The results show that the average sound level is 76dB( A), which is not conformed with the national standard 60dB (A). By analyzing the effect of the interior decoration materials, type and number of sound sources, on the sound environment quality, the paper proposes some feasibility countermeasures of improving the sound environment quality of the cafeteria.%高校食堂是学校师生接触最频繁、最密切的环境之一,是师生们进餐和交流的主要场所,因此研究高校食堂的声环境品质对提高教师和学生的身心健康具有重要的意义。文章采用现场监测方法对学校食堂的声环境质量进行了评价分析,结果显示,机专食堂平均A声级为76分贝,超过了相应的声环境质量标准(60分贝)。通过分析讨论室内装修材料、声源类型和数量等指标对食堂声环境质量的影响,提出了改善学校食堂声环境质量的可行性对策措施。

  12. Application of central venous catheter in hematodialysis%中心静脉置管在血液透析中的应用

    Institute of Scientific and Technical Information of China (English)

    马樱

    2008-01-01

    Objective To approach the application and nursing strategy of central venous catheter in hematodialysis. Meth- ods Sterile operation was strictly done. The nursing of central venous catheter were strengthened. Infection of puncturation and ecchymoma were prevented. Results One hundred and thirty two patients with hematodialysis had been detained central venous catheter for 3 days to 1 months. Only 2 cases of which had infection in puncture point. Pyrogenetic reaction appeared in one case. Five patients developed phlebothrombesis, 3 had mechanical phlebophlogosis. All of above patients were cured by treat- ment. Conclusion It is a normal, safe and effect measure to detain central venous catheter in hematodialysis. The time of detain central venous catheter may be prolong by strengthening nursing, strictly operating in hematodialysis and timely changing dress- ings. Complications involving infection may be reduced.%目的 探讨中心静脉置管在血液透析中的应用和护理对策.方法 严格执行无菌操作,加强中心静脉导管留置过程中的护理,预防穿刺点感染和皮下血肿等并发症出现.结果 留置时间3 d~1个月,132例中发生穿刺点感染2例,其中出现发热反应1例,静脉血栓5例,机械性静脉炎3例,经治疗均好转.结论 中心静脉置管是血液透析最常用、安全和有效的通路,加强中心静脉留置管护理,严格透析操作,按时换药,可延长留王时间,减少感染等并发症.

  13. Central Nervous System-Peripheral Immune System Dialogue in Neurological Disorders: Possible Application of Neuroimmunology in Urology.

    Science.gov (United States)

    Park, Hyun-Sun; Park, Min-Jung; Kwon, Min-Soo

    2016-05-01

    Previous concepts of immune-privileged sites obscured the role of peripheral immune cells in neurological disorders and excluded the consideration of the potential benefits of immunotherapy. Recently, however, numerous studies have demonstrated that the blood-brain barrier in the central nervous system is an educational barrier rather than an absolute barrier to peripheral immune cells. Emerging knowledge of immune-privileged sites suggests that peripheral immune cells can infiltrate these sites via educative gates and that crosstalk can occur between infiltrating immune cells and the central nervous system parenchyma. This concept can be expanded to the testis, which has long been considered an immune-privileged site, and to neurogenic bladder dysfunction. Thus, we propose that the relationship between peripheral immune cells, the brain, and the urologic system should be considered as an additional possible mechanism in urologic diseases, and that immunotherapy might be an alternative therapeutic strategy in treating neurogenic bladder dysfunction.

  14. Deployable centralizers

    Energy Technology Data Exchange (ETDEWEB)

    Grubelich, Mark C.; Su, Jiann-Cherng; Knudsen, Steven D.

    2017-02-28

    A centralizer assembly is disclosed that allows for the assembly to be deployed in-situ. The centralizer assembly includes flexible members that can be extended into the well bore in situ by the initiation of a gas generating device. The centralizer assembly can support a large load carrying capability compared to a traditional bow spring with little or no installation drag. Additionally, larger displacements can be produced to centralize an extremely deviated casing.

  15. Central Breast Excision With Immediate Autologous Reconstruction for Recurrent Periductal Sepsis: An Application of Oncoplastic Surgical Techniques

    OpenAIRE

    Gore, Sinclair M.; WISHART, GORDON C.; Malata, Charles M.

    2012-01-01

    Objective: The aim of this procedure was to definitively treat periductal mastitis and periareolar sepsis which was previously resistant to multiple surgical procedures and nonoperative treatment of chronic nipple sepsis. Methods: We employed a multidisciplinary approach to the treatment of end-stage periductal mastitis using a combination of central breast excision and immediate autologous latissimus dorsi flap reconstruction. Results: Clearance of periductal mastitis and infection has been ...

  16. Application Of Excel In Estimating Central Heating-Supply Project Investment%集中供热工程投资估算中的Excel应用

    Institute of Scientific and Technical Information of China (English)

    杨冬梅

    2012-01-01

    应用Excel计算集中供热工程的投资估算。首先创建估算的模板,再应用模板来计算具体建设规模的投资估算,其应用过程简便、快捷、准确、科学。%This paper use Excel to compute the investment of central heating project.Firstly,it create the estimating template,then used it to compute the investment estimation with specific construction scale.The application process is simple,convenient,rapid,correctly and science.

  17. A statistically based seasonal precipitation forecast model with automatic predictor selection and its application to central and south Asia

    Science.gov (United States)

    Gerlitz, Lars; Vorogushyn, Sergiy; Apel, Heiko; Gafurov, Abror; Unger-Shayesteh, Katy; Merz, Bruno

    2016-11-01

    The study presents a statistically based seasonal precipitation forecast model, which automatically identifies suitable predictors from globally gridded sea surface temperature (SST) and climate variables by means of an extensive data-mining procedure and explicitly avoids the utilization of typical large-scale climate indices. This leads to an enhanced flexibility of the model and enables its automatic calibration for any target area without any prior assumption concerning adequate predictor variables. Potential predictor variables are derived by means of a cell-wise correlation analysis of precipitation anomalies with gridded global climate variables under consideration of varying lead times. Significantly correlated grid cells are subsequently aggregated to predictor regions by means of a variability-based cluster analysis. Finally, for every month and lead time, an individual random-forest-based forecast model is constructed, by means of the preliminary generated predictor variables. Monthly predictions are aggregated to running 3-month periods in order to generate a seasonal precipitation forecast. The model is applied and evaluated for selected target regions in central and south Asia. Particularly for winter and spring in westerly-dominated central Asia, correlation coefficients between forecasted and observed precipitation reach values up to 0.48, although the variability of precipitation rates is strongly underestimated. Likewise, for the monsoonal precipitation amounts in the south Asian target area, correlations of up to 0.5 were detected. The skill of the model for the dry winter season over south Asia is found to be low. A sensitivity analysis with well-known climate indices, such as the El Niño- Southern Oscillation (ENSO), the North Atlantic Oscillation (NAO) and the East Atlantic (EA) pattern, reveals the major large-scale controlling mechanisms of the seasonal precipitation climate for each target area. For the central Asian target areas, both

  18. Central Asia in a Changing World: From a Peripheral Region to an Area of Policy Generation and Application. Actors, Policy and Security

    Directory of Open Access Journals (Sweden)

    Nora Sainz Gsell

    2005-10-01

    Full Text Available This work deals with Central Asia, beginning with an analysis of the characteristics of international insertion of the area as a whole and of the former Soviet republics that comprise it. In a general way, it aims to analyse the evolution of Central Asia from a peripheral region to an area that generates behaviours and receives the application of policies on the part ofinternational actors. In the first part of the study, it mentions a series of particularities of the republics that have determined the relationships in the region(the Central Asian order and those between the region and the outside world; it indicates geo-historical and economic-strategic aspects. In the second part, it examines the foreign policy of the republics in the post-Cold War era from the singularities of domestic policy. And, in the third part, it analyses, according to the aforementioned peculiarities, the policies that the area and each State has generated in international actors, both regional ones and global ones, and which have transformed the region from a peripheral one to a geopolitically emerging one.

  19. CLOSURE OF SMALL CENTRAL PERFORATIONS OF TYMPANIC MEMBRANE WITH GELFILM PATCH AND APPLICATION OF PLATELET RICH PLASMA VERSUS CHEMICAL CAUTERIZATION: A COMPARATIVE STUDY

    Directory of Open Access Journals (Sweden)

    Jeena Kunnathully

    2016-03-01

    Full Text Available BACKGROUND Small central perforation of tympanic membrane is a common finding in patients approaching Otolaryngologists. Even though tympanoplasty can provide a disease free ear and restore hearing loss, most of these cases are either left alone or not surgically treated due to lack of patient compliance. OBJECTIVES In the present study conducted in the Department of Otolaryngology and Head and Neck Surgery, Academy of Medical Sciences, Pariyaram, Kerala, India, we have compared the results of two office procedures for closure of small central perforations. STUDY DESIGN Randomised control trial. METHODS Out of 35 cases with small central perforations of tympanic membrane, 18 were subjected to chemical cauterization with Gelfoam patching and 17 underwent freshening with application of Gelfilm patch and Platelet Rich Plasma (PRP. RESULTS Results were measured in terms of healing of perforation and hearing gain at the end of 3 months. Complete closure was achieved in 54% for chemical cauterization and 53% for Gelfilm patching. The mean hearing gain was 2.17 dB and 2.29 dB respectively. CONCLUSION Smaller size, traumatic aetiology and antero-inferior locations of tympanic membrane perforation showed better results, whereas larger perforations, comorbidities like diabetes mellitus and posteroinferior locations showed poorer results. The complications noted were vertigo, more in chemical cauterization group and otomycosis, more in the freshening and Gelfilm patching group. We thus conclude that all cases of dry small central perforations should be given a trial of either of these cost effective nonsurgical methods before resorting to surgery, depending upon patient compliance.

  20. GIS Applications in Land Management: The Loss of High Quality Land to Development in Central Mississippi from 1987-2002

    Directory of Open Access Journals (Sweden)

    Edmund C. Merem

    2005-08-01

    Full Text Available The socio-economic trends and history of Central Mississippi reveal a major rural influence based upon a dependence on agricultural activities as part of the economic engine driving the state’s economy. Yet, in the last several years, the amount of agricultural land in the counties continues to decline. Similar changes in other variables associated with agricultural land use and the continuity of farming in the state have also been changing. Indeed, under the pressure of urban growth, some farmers are forced to use less productive soils or have abandoned the agricultural business. Considering the gravity of the problem and the implications for sustainable development, public concern has increased in the state of Mississippi that urbanization and other factors may be eroding potential farmland. Given the effects of the current trends on the future capacity to produce food items, there are concerns that the growing incidence of farmland loss may also erode the basis for sustainable use of agricultural land, biodiversity and protection of the state’s ecological treasures. Notwithstanding the gravity of these trends, no major effort in the literature has aimed at documenting the incidence of agricultural land loss and the linkages to urbanization in the region of Central Mississippi. What changes have taken place in the size of agricultural land within the counties and what factors are responsible for it? This paper examines the issue of farmland loss in Central Mississippi with a focus at the county level between 1987 and 2002 from a temporal-spatial perspective. In terms of methodology, the paper uses a mixed scale approach based upon the existing literature. Data were drawn from the United States Census databases of Population and Agriculture. This information is analyzed with basic descriptive statistics and GIS with particular attention to the spatial trends at the county level. Results indicate that the counties under

  1. Addition theorems for Slater-type orbitals and their application to multicenter multielectron integrals of central and noncentral interaction potentials.

    Science.gov (United States)

    Guseinov, Israfil

    2003-06-01

    By the use of complete orthonormal sets of psi(alpha)-ETOs (alpha=1, 0, m1, m2,...) introduced by the author, new addition theorems are derived for STOs and arbitrary central and noncentral interaction potentials (CIPs and NCIPs). The expansion coefficients in these addition theorems are expressed through the Gaunt and Gegenbauer coefficients. Using the addition theorems obtained for STOs and potentials, general formulae in terms of three-center overlap integrals are established for the multicenter t-electron integrals of CIPs and NCIPs that arise in the solution of the N-electron atomic and molecular problem (2hthN) when a Hylleraas approximation in Hartree-Fock-Roothaan theory is employed. With the help of expansion formulae for translation of STOs, the three-center overlap integrals are expressed through the two-center overlap integrals. The formulae obtained are valid for arbitrary quantum numbers, screening constants and location of orbitals.

  2. Central Breast Excision With Immediate Autologous Reconstruction for Recurrent Periductal Sepsis: An Application of Oncoplastic Surgical Techniques

    Science.gov (United States)

    Gore, Sinclair M.; Wishart, Gordon C.; Malata, Charles M.

    2012-01-01

    Objective: The aim of this procedure was to definitively treat periductal mastitis and periareolar sepsis which was previously resistant to multiple surgical procedures and nonoperative treatment of chronic nipple sepsis. Methods: We employed a multidisciplinary approach to the treatment of end-stage periductal mastitis using a combination of central breast excision and immediate autologous latissimus dorsi flap reconstruction. Results: Clearance of periductal mastitis and infection has been achieved with no recurrence at 3 years. Good symmetry of breast shape and volume has been achieved using this technique. Conclusions: This method of partial breast reconstruction, commonly used for reconstruction of breast cancer ablative defects, may also provide good outcomes in nonmalignant disease. PMID:22893784

  3. Oblique-incidence ionospheric soundings over Central Europe and their application for testing now casting and long term prediction models

    Science.gov (United States)

    Pietrella, M.; Perrone, L.; Fontana, G.; Romano, V.; Malagnini, A.; Tutone, G.; Zolesi, B.; Cander, Lj. R.; Belehaki, A.; Tsagouri, I.; Kouris, S. S.; Vallianatos, F.; Makris, J.; Angling, M.

    2009-06-01

    After a first oblique-incidence ionospheric sounding campaign over Central Europe performed during the period 2003-2004 over the radio links between Inskip (UK, 53.5°N, 2.5°W) and Rome (Italy, 41.8°N, 12.5°E) and between Inskip and Chania (Crete, 35.7°N, 24.0°E), new and more extensive analysis of systematic MUF measurements from January 2005 to December 2006 have been performed. MUF measurements collected during moderately disturbed days (17 ⩽ Ap ⩽ 32), disturbed days (32 50), have been used to test the long term prediction models (ASAPS, ICEPAC and SIRM&LKW), and the now casting models (SIRMUP&LKW and ISWIRM&LKW). The performances of the different prediction methods in terms of r.m.s are shown for selected range of geomagnetic activity and for each season.

  4. 中央热送风冲天炉的应用%Application of Central Blast-heating Cupola

    Institute of Scientific and Technical Information of China (English)

    冯英宇; 苏文生

    2011-01-01

    为提高冲天炉的综合性能,通过采取中央集中送风,合理控制风口风速,合理的炉膛结构,防止风嘴熔化等措施.强化焦炭燃烧,增加了焦炭的燃烧比,提高了冲天炉熔炼铁液的出炉温度;能适用混合焦炭,简化了焦炭处理;使炉衬侵蚀减小,修炉简便.通过多年实践改进,完善了中央送风冲天炉的相关工艺参数.该炉型操作简单,有利于降低硅、锰烧损和节能,打炉方便,生产稳定,可在同行业推广.%To improve the overall performance of cupola, taking the measures of centralized air supply, reasonable air control speed, reasonable furnace structurc and preventing the tuyere from mclting, the process of coke combustion is enhanced, the combustion ratio of coke increases and the tapping temperature of cupola melting iron improves. Mixed coke can be applied under the above measures, so the coke processing is simplified, which reduces lining erosion, makes repairing furnace simple. Through practicing and improving in years, the relevant process parameters of central blast-heating cupola are perfected. The cupola is simple in work and stable in production, which can reduce silicon-manganese melting loss and save energy. The cupola is worth of spreading in the same industry.

  5. Oral Administration of Oleuropein and Its Semisynthetic Peracetylated Derivative Prevents Hepatic Steatosis, Hyperinsulinemia, and Weight Gain in Mice Fed with High Fat Cafeteria Diet

    Directory of Open Access Journals (Sweden)

    Saverio Massimo Lepore

    2015-01-01

    Full Text Available The high consumption of olive tree products in the Mediterranean diet has been associated with a lower incidence of metabolic disorders and cardiovascular diseases. In particular, the protective effects of olive oil have been attributed to the presence of polyphenols such as oleuropein (Ole and its derivatives. We have synthesized a peracetylated derivative of Ole (Ac-Ole which has shown in vitro antioxidant and growth-inhibitory activity higher than the natural molecule. In this study, male C57BL/6JOlaHsd mice were fed with a standard (std, cafeteria (caf diet, and caf diet supplemented with Ole (0.037 mmol/kg/day and Ac-Ole (0.025 mmol/kg/day for 15 weeks. We observed a significant reduction in the caf diet-induced body weight gain and increase of abdominal adipose tissue. Also, Ole and Ac-Ole prevented the development of hepatic steatosis. Finally, Ole and Ac-Ole determined a lower increase of HDL and LDL-cholesterol levels and corrected caf diet-induced elevation of plasma glucose concentrations by improving insulin sensitivity. The observed beneficial properties of Ole and Ac-Ole make these compounds and in particular Ac-Ole promising candidates for a potential pharmaceutic use in metabolic disorders.

  6. 网上自助食堂订餐系统的建模%Modeling of the Online Cafeteria Reservation System

    Institute of Scientific and Technical Information of China (English)

    唐莉君

    2012-01-01

    通过统一建模语言UML,利用面向对象的系统分析思想对网上自助食堂订餐系统进行分析,并利用建模工具Rational Rose对系统建立需求模型、基本模型和辅助模型。通过对网上自助食堂订餐系统的分析与建模,阐述了UML在实际中的建模过程和方法,证明UML可以为软件人员减少工作量,为实际开发带来便利。%Based on the Unified Modeling Language (UML),an online cafeteria reservation system is analyzed using object-oriented analysis,and the demand models,basic models and auxiliary models of the system are built with the Rational Rose modeling tool.The practical modeling using UML shows that the UML can reduce the workload of software designers and facilitate development practice.

  7. Foodborne pathogens recovered from ready-to-eat foods from roadside cafeterias and retail outlets in Alice, Eastern Cape Province, South Africa: public health implications.

    Science.gov (United States)

    Nyenje, Mirriam E; Odjadjare, Collins E; Tanih, Nicoline F; Green, Ezekiel; Ndip, Roland N

    2012-08-01

    This study assessed the microbiological quality of various ready-to-eat foods sold in Alice, South Africa. Microbiological analysis was conducted on 252 samples which included vegetables, potatoes, rice, pies, beef and chicken stew. The isolates were identified using biochemical tests and the API 20E, API 20NE and API Listeria kits; results were analyzed using the one-way-ANOVA test. Bacterial growth was present in all the food types tested; high levels of total aerobic count were observed in vegetables, 6.8 ± 0.07 followed by rice, 6.7 ± 1.7 while pies had the lowest count (2.58 ± 0.24). Organisms isolated included: Listeria spp. (22%), Enterobacter spp. (18%), Aeromonas hydrophila (12%), Klebsiella oxytoca (8%), Proteus mirabilis (6.3%), Staphylococcus aureus (3.2%) and Pseudomonas luteola (2.4%). Interestingly, Salmonella spp. and Escherichia coli were not isolated in any of the samples. There was a statistically significant difference (p cafeterias. The results indicated that most of the ready-to-eat food samples examined in this study did not meet bacteriological quality standards, therefore posing potential risks to consumers. This should draw the attention of the relevant authorities to ensure that hygienic standards are improved to curtain foodborne infections.

  8. ANTI-OBESITY PROPERTY OF HEXANE EXTRACT FROM THE LEAVES OF GYMNEMA SYLVESTRE IN HIGH FED CAFETERIA DIET INDUCED OBESITY RATS

    Directory of Open Access Journals (Sweden)

    Kaushik Manish

    2011-08-01

    Full Text Available The hexane extract of leaves of Gymnema sylvestre was evaluated for its anti-obesity activity in the simplified high fed cafeteria diet induced obesity in Sprague dawley rats. Group-I (normal control were fed on only basal diet without any treatment, Group-II (obesity control were induced obesity and only on basal diet without any treatment, Group-III and Group IV were induced obesity and treated with hexane fraction of Gymnema sylvestre (150 mg/kg and 250 mg/kg body weight respectively. Group V were induced obesity and treated with Atorvastatin as a standard drug. A significant (P>0.001 reduce in increased body weight, temperature due to obesity was observed after 45th day of treatment as compared to the normal and standard group. The extract also improved the cholesterol, triglyceride, LDL and HDL level. Blood samples were collected from retro-orbital plexus. Observed data was found statistically significant in reduction of extract-treated obesity rats. The effect of the extract was comparable to that of standard drug Atorvastatin (50mg/kg body weight.

  9. Reliability and accuracy of real-time visualization techniques for measuring school cafeteria tray waste: validating the quarter-waste method.

    Science.gov (United States)

    Hanks, Andrew S; Wansink, Brian; Just, David R

    2014-03-01

    Measuring food waste is essential to determine the impact of school interventions on what children eat. There are multiple methods used for measuring food waste, yet it is unclear which method is most appropriate in large-scale interventions with restricted resources. This study examines which of three visual tray waste measurement methods is most reliable, accurate, and cost-effective compared with the gold standard of individually weighing leftovers. School cafeteria researchers used the following three visual methods to capture tray waste in addition to actual food waste weights for 197 lunch trays: the quarter-waste method, the half-waste method, and the photograph method. Inter-rater and inter-method reliability were highest for on-site visual methods (0.90 for the quarter-waste method and 0.83 for the half-waste method) and lowest for the photograph method (0.48). This low reliability is partially due to the inability of photographs to determine whether packaged items (such as milk or yogurt) are empty or full. In sum, the quarter-waste method was the most appropriate for calculating accurate amounts of tray waste, and the photograph method might be appropriate if researchers only wish to detect significant differences in waste or consumption of selected, unpackaged food.

  10. Distributed Assessment of Network Centrality

    CERN Document Server

    Wehmuth, Klaus

    2011-01-01

    We propose a method for the Distributed Assessment of Network CEntrality (DANCE) in complex networks. DANCE attributes to each node a volume-based centrality computed using only localized information, thus not requiring knowledge of the full network topology. We show DANCE is simple, yet efficient, in assessing node centrality in a distributed way. Our proposal also provides a way for locating the most central nodes, again using only the localized information at each node. We also show that the node rankings based on DANCE's centrality and the traditional closeness centrality correlate very well. This is quite useful given the vast potential applicability of closeness centrality, which is however limited by its high computational costs. We experimentally evaluate DANCE against a state-of-the-art proposal to distributively assess network centrality. Results attest that DANCE achieves similar effectiveness in assessing network centrality, but with a significant reduction in the associated costs for practical ap...

  11. Application of Pressure Equipment Standard at nuclear power plants; Aplicacion del Reglamento de Equipos a Presion a las centrales nucleares

    Energy Technology Data Exchange (ETDEWEB)

    Mostaza, J. M.

    2011-07-01

    Regarding with the paper presented on 9{sup t}h June 2011 referred to the Industrial Security standard in Nuclear Plants, it was about the application of Pressure Equipment standard to mentioned Nuclear Plants, this article is an extract of the paper going to be exposed. (Author)

  12. Application of Response Surface Methodology and Central Composite Inscribed Design for Modeling and Optimization of Marble Surface Quality

    Directory of Open Access Journals (Sweden)

    Sümeyra Cevheroğlu Çıra

    2016-01-01

    Full Text Available Factors affecting the final surface quality of polished marble are not yet fully understood. Clarifying these factors for optimization of multivariate polishing process by trial and error method is difficult, time-consuming, and costly task. In this study, the empirical practices were carried out using an experimental design, specifically, a central composite inscribed (CCI design. The factors considered in CCI design were belt speed, rotational speed, and pressure of the polishing head, and the responses were surface glossiness and roughness. Mathematical models describing responses were produced using experimental datasets, and analysis of variance (ANOVA was used to assess the fit of the models generated with the experimental data. For process optimization, desirability function analysis (DFA was used. This study has shown that the CCI could efficiently be applied for the modelling of polishing machine for surface quality of marble strips. Better surface quality generally resulted from lower belt speeds, which increased contact time between the abrasives and strips. Optimized surface quality for marble specimen was established.

  13. Application of central composite design to optimize the amount of carbon source and prebiotics for Bifidobacterium bifidum BB01

    Directory of Open Access Journals (Sweden)

    Shu Guowei

    2016-06-01

    Full Text Available The objective of the present study was to obtain the optimum proportion of the carbon source and prebiotics for Bifidobacterium bifidum BB01 by the central composite design (CCD. The effect of carbon source (lactose and two prebiotics (inulin and fructooligosaccharides on the BB01 were observed by measuring the OD600 value, pH value and the viable counts at 18h. The final optimized concentrations of carbon source and prebiotics were: lactose 1.6%, inulin 0.26%, and fructooligosaccharides 0.22%. The result indicates that the growth of B. bifidum BB01 shows an significant increase in the optimized culture medium (p < 0.05, the OD600 value reached 1.434 at 18h, which increased 6.58% compared to the control. And the viable counts of B. bifidum BB01 increased 24.36% and reached (2.17±0.06 ×109cfu/mL. The results show that the optimization of the carbon source and prebiotics using CCD in this study is workable and necessary.

  14. Ground-water temperature of the Wyoming quadrangle in central Delaware : with application to ground-water-source heat pumps

    Science.gov (United States)

    Hodges, Arthur L.

    1982-01-01

    Ground-water temperature was measured during a one-year period (1980-81) in 20 wells in the Wyoming Quadrangle in central Delaware. Data from thermistors set at fixed depths in two wells were collected twice each week, and vertical temperature profiles of the remaining 18 wells were made monthly. Ground-water temperature at 8 feet below land surface in well Jc55-1 ranged from 45.0 degrees F in February to 70.1 degrees F in September. Temperature at 35 feet below land surface in the same well reached a minimum of 56.0 degrees F in August, and a maximum of 57.8 degrees F in February. Average annual temperature of ground water at 25 feet below land surface in all wells ranged from 54.6 degrees F to 57.8 degrees F. Variations of average temperature probably reflect the presence or absence of forestation in the recharge areas of the wells. Ground-water-source heat pumps supplied with water from wells 30 or more feet below land surface will operate more efficiently in both heating and cooling modes than those supplied with water from shallower depths. (USGS)

  15. The Central Point and Applicant of DHI%DHI技术的关键点及数据应用分析

    Institute of Scientific and Technical Information of China (English)

    赵秀新; 李建斌; 侯明海; 仲跻峰

    2014-01-01

    奶牛生产性能测定(DairyHerdImprovement,DHI),又称奶牛群改良,旨在对奶牛泌乳性能及乳成分进行测定并建立完整的记录体系,也是奶牛数字化育种技术的核心和基础。通过应用DHI技术为奶农提供指导服务,可以产生巨大的经济效益;其次,还可以为青年公牛后裔测定、种子母牛群组建、选种选配等育种工作提供数据支持。本文对DHI技术的关键点和报告解读技巧进行综述,以期指导生产实践。%Dairy herd improvement (DHI), establish a formal record system for the lactation performance and milk composition of dairy cattle. It is the basic and central system for dairy cattle digital breeding. A huge economical beneift can be achieved by the application of DHI for dairy farmers. It also makes a huge contribution for progency test of youngbull, elite cow herd building, selection and mating. This article is going to discuss the central point of DHI test for implementation.

  16. A hybrid symplectic principal component analysis and central tendency measure method for detection of determinism in noisy time series with application to mechanomyography

    Science.gov (United States)

    Xie, Hong-Bo; Dokos, Socrates

    2013-06-01

    We present a hybrid symplectic geometry and central tendency measure (CTM) method for detection of determinism in noisy time series. CTM is effective for detecting determinism in short time series and has been applied in many areas of nonlinear analysis. However, its performance significantly degrades in the presence of strong noise. In order to circumvent this difficulty, we propose to use symplectic principal component analysis (SPCA), a new chaotic signal de-noising method, as the first step to recover the system dynamics. CTM is then applied to determine whether the time series arises from a stochastic process or has a deterministic component. Results from numerical experiments, ranging from six benchmark deterministic models to 1/f noise, suggest that the hybrid method can significantly improve detection of determinism in noisy time series by about 20 dB when the data are contaminated by Gaussian noise. Furthermore, we apply our algorithm to study the mechanomyographic (MMG) signals arising from contraction of human skeletal muscle. Results obtained from the hybrid symplectic principal component analysis and central tendency measure demonstrate that the skeletal muscle motor unit dynamics can indeed be deterministic, in agreement with previous studies. However, the conventional CTM method was not able to definitely detect the underlying deterministic dynamics. This result on MMG signal analysis is helpful in understanding neuromuscular control mechanisms and developing MMG-based engineering control applications.

  17. Relationships between statistics of rainfall extremes and mean annual precipitation: an application for design-storm estimation in northern central Italy

    Directory of Open Access Journals (Sweden)

    G. Di Baldassarre

    2006-01-01

    Full Text Available Several hydrological analyses need to be founded on a reliable estimate of the design storm, which is the expected rainfall depth corresponding to a given duration and probability of occurrence, usually expressed in terms of return period. The annual series of precipitation maxima for storm duration ranging from 15 min to 1 day, observed at a dense network of raingauges sited in northern central Italy, are analyzed using an approach based on L-moments. The analysis investigates the statistical properties of rainfall extremes and detects significant relationships between these properties and the mean annual precipitation (MAP. On the basis of these relationships, we developed a regional model for estimating the rainfall depth for a given storm duration and recurrence interval in any location of the study region. The applicability of the regional model was assessed through Monte Carlo simulations. The uncertainty of the model for ungauged sites was quantified through an extensive cross-validation.

  18. Profile of central research and application laboratory of Aǧrı İbrahim Çeçen University

    Science.gov (United States)

    Türkoǧlu, Emir Alper; Kurt, Murat; Tabay, Dilruba

    2016-04-01

    Aǧrı İbrahim Çeçen University built a central research and application laboratory (CRAL) in the east of Turkey. The CRAL possesses 7 research and analysis laboratories, 12 experts and researchers, 8 standard rooms for guest researchers, a restaurant, a conference hall, a meeting room, a prey room and a computer laboratory. The CRAL aims certain collaborations between researchers, experts, clinicians and educators in the areas of biotechnology, bioimagining, food safety & quality, omic sciences such as genomics, proteomics and metallomics. It also intends to develop sustainable solutions in agriculture and animal husbandry, promote public health quality, collect scientific knowledge and keep it for future generations, contribute scientific awareness of all stratums of society, provide consulting for small initiatives and industries. It has been collaborated several scientific foundations since 2011.

  19. Log ASCII Standard (LAS) Files for Geophysical (Gamma Ray) Wireline Well Logs and Their Application to Geologic Cross Section C-C' Through the Central Appalachian Basin

    Science.gov (United States)

    Trippi, Michael H.; Crangle, Robert D.

    2009-01-01

    U.S. Geological Survey (USGS) regional geologic cross section C-C' (Ryder and others, 2008) displays key stratigraphic intervals in the central Appalachian basin. For this cross section, strata were correlated by using descriptions of well cuttings and gamma ray well log traces. This report summarizes the procedures used to convert gamma ray curves on paper well logs to the digital Log ASCII (American Standard Code for Information Interchange) Standard (LAS) format using the third-party software application Neuralog. The procedures could be used with other geophysical wireline logs also. The creation of digital LAS files from paper well logs by using Neuralog is very helpful, especially when dealing with older logs with limited or nonexistent digital data. The LAS files from the gamma ray logs of 11 wells used to construct cross section C-C' are included in this report. They may be downloaded from the index page as a single ZIP file.

  20. Application of microtremor array measurements to delineate S-wave velocity structures in Bangkok Basin, central Thailand

    Science.gov (United States)

    Hayashi, K.; Pananont, P.; Wongpanit, T.; Habangkham, S.

    2014-12-01

    The Bangkok Basin, located in the lower part of the Chao Phraya River Basin in central Thailand contains very thick sediment and are often affected by the large distant earthquakes due to local site amplification. Shear wave velocities (Vs) measurements have been performed at five sites in the Bangkok Basin (Figure 1) by a two-station spatial autocorrelation method (2ST-SPAC) using long-period accelerometers. Receiver separation varied from 5 to 2,100m and maximum separation (array size) varied from 1,800 to 2,100 m. In each separation, 10 to 90 minutes ambient noise was recorded with sampling interval of 10 ms. Due to the security concern, data acquisition was performed in the day-time and in relatively quiet places such as in parks or less densely residential areas. A spatial autocorrelation was used for calculating phase velocity and clear dispersion curves were obtained in frequency range from about 0.3 to 10 Hz. Minimum frequency and corresponding maximum wavelength ranged from 0.32 to 0.48 Hz and about 2,180 to 5,140 m, depending on the site. An inversion consisting of a least squares method and a Genetic Algorithm was used to estimate Vs profiles from the dispersion curves to a depth of about 1,000 to 2,500 m depending on the sites. Figure 2 shows comparison of Vs profiles obtained by the inversion. We can see that a low velocity layer with Vs lower than 400 m/s exists between depths of 0 to 200 m at all sites. Intermediate bedrock with Vs higher than 1,000 m/s exists between depths of 240 to 1,250 m. Deepest bedrock with Vs higher than 2,000 m/s seems to exist at a depth of at least 1,600 m.

  1. Application of sensitivity analysis for assessment of de-desertification alternatives in the central Iran by using Triantaphyllou method.

    Science.gov (United States)

    Sadeghi Ravesh, Mohammad Hassan; Ahmadi, Hassan; Zehtabian, Gholamreza

    2011-08-01

    Desertification, land degradation in arid, semi-arid, and dry sub-humid regions, is a global environmental problem. With respect to increasing importance of desertification and its complexity, the necessity of attention to the optimal de-desertification alternatives is essential. Therefore, this work presents an analytic hierarchy process (AHP) method to objectively select the optimal de-desertification alternatives based on the results of interviews with experts in Khezr Abad region, central Iran as the case study. This model was used in Yazd Khezr Abad region to evaluate the efficiency in presentation of better alternatives related to personal and environmental situations. Obtained results indicate that the criterion "proportion and adaptation to the environment" with the weighted average of 33.6% is the most important criterion from experts viewpoints. While prevention alternatives of land usage unsuitable of reveres and conversion with 22.88% mean weight and vegetation cover development and reclamation with 21.9% mean weight are recognized ordinarily as the most important de-desertification alternatives in region. Finally, sensitivity analysis is performed in detail by varying the objective factor decision weight, the priority weight of subjective factors, and the gain factors. After the fulfillment of sensitivity analysis and determination of the most sensitive criteria and alternatives, the former classification and ranking of alternatives does not change so much, and it was observed that unsuitable land use alternative with the preference degree of 22.7% was still in the first order of priority. The final priority of livestock grazing control alternative was replaced with the alternative of modification of ground water harvesting.

  2. Application of IEUBK model in lead risk assessment of children aged 61–84 months old in central China

    Energy Technology Data Exchange (ETDEWEB)

    Li, Yanyan [MOE Key Lab of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei (China); Hu, Jia [Suzhou Center for Disease Prevention and Control, Suzhou, Jiangsu (China); Wu, Wei [MOE Key Lab of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei (China); Liu, Shuyun [Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei (China); Li, Mei [Hanyang Center for Disease Prevention and Control, Wuhan, Hubei (China); Yao, Na; Chen, Jianwei [MOE Key Lab of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei (China); Ye, Linxiang [Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei (China); Wang, Qi, E-mail: lwq95@126.com [MOE Key Lab of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei (China); Department of Epidemiology and Biostatistics, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei (China); Zhou, Yikai, E-mail: zhouyk@mails.tjmu.edu.cn [MOE Key Lab of Environment and Health, Institute of Environmental Medicine, School of Public Health, Tongji Medical College, Huazhong University of Science & Technology, Wuhan, Hubei (China)

    2016-01-15

    Few studies have focused on the accuracy of using the Integrated Exposure Uptake Biokinetic (IEUBK) model in Chinese children with site- and age-specific exposure data. This study aimed to validate the accuracy and sensitivity of the IEUBK model in lead risk assessment of Chinese children aged 61–84 months old. A total of 760 children were enrolled from two respective counties in Central China by using random cluster sampling method. Blood lead levels (BLLs) of all subjects were determined using graphite furnace atomic absorption spectrometry, as well as that in the environmental media, such as air, drinking water, soil, dust and food. Age- and site-specific time-activity patterns and water consumption were evaluated by using questionnaires for children. Exposure parameters including outdoor and indoor activity time, ventilation rate and water consumption in this study were different from the default values of the IEUBK model. Statistical analysis revealed no significant differences between the predicted and observed BLLs. Diet and soil/dust lead intake contributed approximately 83.39% (57.40%–93.84% range) and 15.18% (3.25%–41.60% range) of total lead intake, respectively. These findings showed that the IEUBK model is suitable for lead risk assessment of Chinese children aged 61–84 months old and diet acts as an important lead source. - Highlights: • The first time to fit and discuss the IEUBK model in China based on comprehensive local children exposure parameters. • Two different exposure scenarios to apply the IEUBK model in different conditions. • The first time to report the ventilation rate in Chinese children aged 61 to 84 months. • Highlight the role of dietary to lead intake for Chinese children.

  3. Reconstitution of a Continuous Climatic and Rainfall Series for the Central Sahel (1950-2012): Data, Methodology and Application

    Science.gov (United States)

    Leauthaud, C.; Demarty, J.; Cappelaere, B.; Vischel, T.; Guichard, F.; Kergoat, L.; Manuela, G.; Hourdin, F.; Sultan, B.

    2014-12-01

    detailed LSM/SVAT model (SiSPAT). This dataset could be used by the community to better understand and predict land-surface-atmosphere interactions in Central Sahel, including hydrological ones, such as historical changes in yield, growth of natural vegetation, changes in the water cycle and as a high-quality baseline for climate change impacts studies.

  4. Multi-modeling assessment of recent changes in groundwater resource: application to the semi-arid Haouz plain (Central Morocco)

    Science.gov (United States)

    Fakir, Younes; Brahim, Berjamy; Page Michel, Le; Fathallah, Sghrer; Houda, Nassah; Lionel, Jarlan; Raki Salah, Er; Vincent, Simonneaux; Said, Khabba

    2015-04-01

    The Haouz plain (6000 km2) is a part of the Tensift basin located in the Central Morocco. The plain has a semi-arid climate (250 mm/y of rainfall) and is bordered in the south by the High-Atlas mountains. Because the plain is highly anthropized, the water resources face heavy demands from various competing sectors, including agriculture (over than 273000 ha of irrigated areas), water supply for more than 2 million inhabitants and about 2 millions of tourists annually. Consequently the groundwater is being depleted on a large area of the plain, with problems of water scarcity which pose serious threats to water supplies and to sustainable development. The groundwater in the Haouz plain was modeled previously by MODFLOW (USGS groundwater numerical modeling) with annual time steps. In the present study a multi-modeling approach is applied. The aim is to enhance the evaluation of the groundwater pumping for irrigation, one of the most difficult data to estimate, and to improve the water balance assessment. In this purpose, two other models were added: SAMIR (Satellite Estimation of Agricultural Water Demand) and WEAP (integrated water resources planning). The three models are implemented at a monthly time step and calibrated over the 2001-2011 period, corresponding to 120 time steps. This multi-modeling allows assessing the evolution of water resources both in time and space. The results show deep changes during the last years which affect generally the water resources and groundwater particularly. These changes are induced by a remarkable urbanism development, succession of droughts, intensive agriculture activities and weak management of irrigation and water resources. Some indicators of these changes are as follow: (i) the groundwater table decrease varies between 1 to 3m/year, (ii) the groundwater depletion during the last ten year is equivalent to 50% of the lost reserves during 40 years, (iii) the annual groundwater deficit is about 100 hm3, (iv) the renewable

  5. A METHOD OF SUPERIMPOSED TRIANGULATIONS FOR CALCULATION OF VELOCITY GRADIENT OF HORIZONTAL MOVEMENTS: APPLICATION TO THE CENTRAL ASIAN GPS NETWORK

    Directory of Open Access Journals (Sweden)

    Alexander V. Zubovich

    2015-09-01

    Full Text Available A new method is proposed to define piecewise continuous fields of velocity gradients of recent horizontal movements of the Earth’s crust from spatially discrete data on horizontal velocities of such movements. The method is designed to identify spatial inhomogeneities in the field of horizontal strain rates (e.g., zones of localized deformation and boundaries between areas with different strain rates in considerable detail. It is applied to determine the field of horizontal velocity gradient in the region of the Central Asian GPS network which covers vast territories of the Kyrgyz Tien-Shan and Pamirs mountain ranges, the T arim depression, and the Kazakh Shield (Fig. 1. Calculations are based on GPS survey data obtained at 308 sites from 1995 to 2006 (Fig. 4. The resolution of the proposed method is increased by using a triangulation grid which is much denser than a conventional one (Fig. 2 and 3. As a result, point x on the surface under study is covered by several triangles rather than one (Fig. 5. Strain characteristics at point x are calculated by weighted summation of corresponding characteristics in the cover triangles. Thus, for each point we estimate spin tensor W, which defines angular velocity ω, and components of horizontal strain rate tensor E. These components provide for direct calculation of orientation of principal axes and invariants of E, i.e. maximum stretching E1, maximum shortening E2, velocity divergence E=E1+E2, and maximum shear rates Γ=⎪E1−E2⎪/2 (Fig. 6 to 11. The calculated values are presented in maps which demonstrate that spatial distribution of such values is highly inhomogeneous. Regions with increased values of kinematic characteristics mentioned above stand out sharply against the background. At the same time, spatial distribution of the kinematical characteristics in the Tien Shan region is quite regular: zones of increased absolute values of E2 are mainly oriented in the ENE direction, while the NNW

  6. Single-earthquake Location Using 3-D Vp and Vs Model - Applications in the Central USA and Taiwan Regions

    Science.gov (United States)

    Chiu, J.; Chen, H.; Kim, K.; Pujol, J.; Chiu, S.; Withers, M.

    2003-12-01

    Traditional local earthquake location using a horizontally layered homogeneous velocity model is always limited in its resolution and reliability due to the existence of frequently overlooked 3- dimensional complexity of the real earth. Simultaneous earthquake relocation during a traditional 3-D seismic tomography has only applied to a limited set of selected earthquakes that more than 50% of earthquakes in a catalog are basically ignored. A new earthquake location program has been developed to locate every local earthquake using the best available 3-D Vp and Vs model for a region. Many modern seismic networks have provided excellent spatial coverage of seismic stations to record high-resolution earthquake data to allow the determination of high-resolution 3-D Vp and Vs velocity model for the region. Once Vp and Vs information for all 3-D grid points are available, travel time from each grid point to all seismic stations can be calculated using any available 3-D ray tracing techniques and be stored in computer files for later usage. Travel times from a trial hypocenter to the recording stations can be interpolated simply from those of the adjacent 8 grid points available in computer files without the very time consuming 3-D ray tracing. Iterations continue until the hypocenter adjustments are less than the given criteria and the travel time residual, or the difference between the observed and the calculated travel times, is a minimum. Therefore, any earthquake, no matter how small or how big it is, will be efficiently and reliably located using the 3-D velocity model. This new location program has been applied to the New Madrid seismic zone of the central USA and in various seismic zones in Taiwan region. Preliminary results in these two regions indicate that earthquake hypocenters can be reliably relocated in spite of the very significant lateral structural variations. This location program can also be applied in routine earthquake location for any seismic network

  7. Combination of the sodium-glucose cotransporter-2 inhibitor empagliflozin with orlistat or sibutramine further improves the body-weight reduction and glucose homeostasis of obese rats fed a cafeteria diet

    Directory of Open Access Journals (Sweden)

    Vickers SP

    2014-07-01

    Full Text Available Steven P Vickers,1 Sharon C Cheetham,1 Katie R Headland,1 Keith Dickinson,1 Rolf Grempler,2 Eric Mayoux,2 Michael Mark,2 Thomas Klein2 1RenaSci, BioCity Nottingham, Nottingham, UK; 2Boehringer Ingelheim Pharma, Biberach an der Riss, Germany Abstract: The present study assessed the potential of the sodium glucose-linked transporter (SGLT-2 inhibitor empagliflozin to decrease body weight when administered alone or in combination with the clinically effective weight-loss agents orlistat and sibutramine in obese rats fed a cafeteria diet. Female Wistar rats were exposed to a cafeteria diet to induce obesity. Empagliflozin was dosed once daily (10, 30, and 60 mg/kg for 28 days. Combination studies were subsequently performed using a submaximal empagliflozin dose (10 mg/kg with either sibutramine or orlistat. Body weight, food, and water intake were recorded daily. The effect of drug treatment on glucose tolerance, relevant plasma parameters, and carcass composition was determined. Empagliflozin dose-dependently reduced body weight, plasma leptin, and body fat though increased urinary glucose excretion. The combination of empagliflozin and orlistat significantly reduced body weight compared to animals treated with either drug alone, and significantly improved glucose tolerance, plasma insulin, and leptin compared to vehicle-treated controls. The effect of sibutramine to improve glycemic control in an oral glucose-tolerance test was also significantly increased, with empagliflozin and combination treatment leading to a reduction in carcass fat greater than that observed with either drug alone. These data demonstrate that empagliflozin reduces body weight in cafeteria-fed obese rats. In combination studies, empagliflozin further improved the body-weight or body-fat loss of animals in comparison to orlistat or sibutramine alone. Such studies may indicate improved strategies for the treatment of obese patients with prediabetes or type 2 diabetes. Keywords

  8. Vulnerability assessment of karst aquifer feeding Pertuso Spring (Central Italy): comparison between different applications of COP method

    Science.gov (United States)

    Sappa, Giuseppe; Ferranti, Flavia; Luciani, Giulia

    2016-04-01

    Vulnerability assessment of karst aquifers and vulnerability mapping are important tools for improved sustainable management and protection of karst groundwater resources. In this paper, to estimate the vulnerability degree of the karst aquifer feeding Pertuso Spring in Central Italy, two different implementations of COP method, supported by an open source GIS, were tested and a comparison of the vulnerability maps is proposed. The study area is a highly karstified carbonate aquifer located in the Upper Valley of the Aniene River, in the south-east part of Latium Region. The hydrogeological basin covers about 50 km2 and the karst aquifer provides a water supply of about 120.000 m3d-1. The well-developed karst features in this hydrogeological system is responsible of the fast infiltration of rainfall in the saturated zone and, consequently, of the high discharge rate of Pertuso Spring (up to 3 m3/s). Thus, in the aim of emphasizing the presence of these karst features, due to which, there are limited attenuation processes in the unsaturated zone, in this work COP method has been applied by the implementation of a new discretization methodology of the hydrogeological basin using polygonal layer. Therefore, the hydrogeological catchment basin has been divided into 52 polygonal layer, representative of outcropping lithology and karst features, to which COP method has been applied. The intrinsic vulnerability maps, produced using a GIS approach, has been examinated and compared with the maps obtained using traditional vulnerability assessment method, which provides the discretization of the study area generating a grid map to which associate the Vulnerability Indexes. The results of this study highlight vulnerability from low to very high. The maximum vulnerability degree is due to karstic features responsible of high recharge and high hydraulic conductivity. The new proposed discretization of the hydrogeological basin using polygonal layer raise four vulnerability

  9. Foodborne Pathogens Recovered from Ready-to-Eat Foods from Roadside Cafeterias and Retail Outlets in Alice, Eastern Cape Province, South Africa: Public Health Implications

    Directory of Open Access Journals (Sweden)

    Roland N. Ndip

    2012-07-01

    Full Text Available This study assessed the microbiological quality of various ready-to-eat foods sold in Alice, South Africa. Microbiological analysis was conducted on 252 samples which included vegetables, potatoes, rice, pies, beef and chicken stew. The isolates were identified using biochemical tests and the API 20E, API 20NE and API Listeria kits; results were analyzed using the one-way-ANOVA test. Bacterial growth was present in all the food types tested; high levels of total aerobic count were observed in vegetables, 6.8 ± 0.07 followed by rice, 6.7 ± 1.7 while pies had the lowest count (2.58 ± 0.24. Organisms isolated included: Listeria spp. (22%, Enterobacter spp. (18%, Aeromonas hydrophila (12%, Klebsiella oxytoca (8%, Proteus mirabilis (6.3%, Staphylococcus aureus (3.2% and Pseudomonas luteola (2.4%. Interestingly, Salmonella spp. and Escherichia coli were not isolated in any of the samples. There was a statistically significant difference (p < 0.05 in the prevalence of foodborne pathogens from hygienic and unhygienic cafeterias. The results indicated that most of the ready-to-eat food samples examined in this study did not meet bacteriological quality standards, therefore posing potential risks to consumers. This should draw the attention of the relevant authorities to ensure that hygienic standards are improved to curtain foodborne infections.

  10. Modern 'junk food' and minimally-processed 'natural food' cafeteria diets alter the response to sweet taste but do not impair flavor-nutrient learning in rats.

    Science.gov (United States)

    Palframan, Kristen M; Myers, Kevin P

    2016-04-01

    Animals learn to prefer and increase consumption of flavors paired with postingestive nutrient sensing. Analogous effects have been difficult to observe in human studies. One possibility is experience with the modern, processed diet impairs learning. Food processing manipulates flavor, texture, sweetness, and nutrition, obscuring ordinary correspondences between sensory cues and postingestive consequences. Over time, a diet of these processed 'junk' foods may impair flavor-nutrient learning. This 'flavor-confusion' hypothesis was tested by providing rats long-term exposure to cafeteria diets of unusual breadth (2 or 3 foods per day, 96 different foods over 3 months, plus ad libitum chow). One group was fed processed foods (PF) with added sugars/fats and manipulated flavors, to mimic the sensory-nutrient properties of the modern processed diet. Another group was fed only 'natural' foods (NF) meaning minimally-processed foods without manipulated flavors or added sugars/fats (e.g., fresh fruits, vegetables, whole grains) ostensibly preserving the ordinary correspondence between flavors and nutrition. A CON group was fed chow only. In subsequent tests of flavor-nutrient learning, PF and NF rats consistently acquired strong preferences for novel nutrient-paired flavors and PF rats exhibited enhanced learned acceptance, contradicting the 'flavor-confusion' hypothesis. An unexpected finding was PF and NF diets both caused lasting reduction in ad lib sweet solution intake. Groups did not differ in reinforcing value of sugar in a progressive ratio task. In lick microstructure analysis the NF group paradoxically showed increased sucrose palatability relative to PF and CON, suggesting the diets have different effects on sweet taste evaluation.

  11. Bergamot polyphenol fraction prevents nonalcoholic fatty liver disease via stimulation of lipophagy in cafeteria diet-induced rat model of metabolic syndrome.

    Science.gov (United States)

    Parafati, Maddalena; Lascala, Antonella; Morittu, Valeria Maria; Trimboli, Francesca; Rizzuto, Antonia; Brunelli, Elvira; Coscarelli, Francesca; Costa, Nicola; Britti, Domenico; Ehrlich, James; Isidoro, Ciro; Mollace, Vincenzo; Janda, Elzbieta

    2015-09-01

    Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease in industrialized countries. Defective autophagy of lipid droplets (LDs) in hepatocytes, also known as lipophagy, has recently been identified as a possible pathophysiological mechanism of NAFLD. Experimental and epidemiological evidence suggests that dietary polyphenols may prevent NAFLD. To address this hypothesis and analyze the underlying mechanisms, we supplemented bergamot polyphenol fraction (BPF) to cafeteria (CAF) diet-fed rats, a good model for pediatric metabolic syndrome and NAFLD. BPF treatment (50 mg/kg/day supplemented with drinking water, 3 months) potently counteracted the pathogenic increase of serum triglycerides and had moderate effects on blood glucose and obesity in this animal model. Importantly, BPF strongly reduced hepatic steatosis as documented by a significant decrease in total lipid content (-41.3% ± 12% S.E.M.), ultrasound examination and histological analysis of liver sections. The morphometric analysis of oil-red stained sections confirmed a dramatic reduction in LDs parameters such as total LD area (48.5% ± 15% S.E.M.) in hepatocytes from CAF+BPF rats. BPF-treated livers showed increased levels of LC3 and Beclin 1 and reduction of SQSTM1/p62, suggesting autophagy stimulation. Consistent with BPF stimulation of lipophagy, higher levels of LC3II were found in the LD subcellular fractions of BPF-expose livers. This study demonstrates that the liver and its lipid metabolism are the main targets of bergamot flavonoids, supporting the concept that supplementation of BPF is an effective strategy to prevent NAFLD.

  12. Autologous Bone Marrow Stromal Cell Transplantation for Central Nervous System Disorders – Recent Progress and Perspective for Clinical Application

    Directory of Open Access Journals (Sweden)

    Kuroda S

    2011-01-01

    Full Text Available There is increasing evidence that the transplanted BMSC significantly promote functional recovery after CNS damage in the animal models of various kinds of CNS disorders, including cerebral infarct, traumatic brain injury and spinal cord injury. However, there are several shortages of information when considering clinical application of BMSC transplantation for patients with CNS disorders. In this review, therefore, we discuss what we should clarify to establish cell transplantation therapy as the scientifically proven entity in clinical situation and describe our recent works for this purpose. The BMSC have the ability to alter their gene expression profile and phenotype in response to the surrounding circumstances and to protect the neurons by producing some neurotrophic factors. They also promote neurite extension and rebuild the neural circuits in the injured CNS. The BMSC can be expanded in vitro using the animal serum-free medium. Pharmacological modulation may accelerate the in vitro proliferation of the BMSC. Using in vivo optical imaging technique, the transplanted BMSC can non-invasively be tracked in the living animals for at least 8 weeks after transplantation. It is urgent issues to develop clinical imaging technique to track the transplanted cells in the CNS and evaluate the therapeutic significance of BMSC transplantation in order to establish it as a definite therapeutic strategy in clinical situation in the future.

  13. Central Bank autonomy in Europe and Latin America: analysis of differences and applications Autonomía de la banca central en Europa y América Latina

    Directory of Open Access Journals (Sweden)

    Rollinat Robert

    1996-06-01

    Full Text Available This article makes a comparative analysis of the experiences of the independent central bank in Latin America and Europe. After reviewing the problems and theories of central bank autonomy, it studies the recent evolution of the Latin American central bank in comparison with the European central bank, high lights the perverse effects of the reforms, and shows that their objective is more the stability of the financial system than the stability of prices. Finally, it describes the tests to which the new Latin American central banks have been subjected and the effects on their credibility. It concludes that these entities have had to correct and pay for the incoherences and errors of the market, and that their independence or autonomy depends on their continuing to ful fill this role, not only for economíc or monetary reasons but for the needs of political and social democracy.Este artículo hace un análisis comparativo de las experiencias de la banca central independiente en América Latina y Europa. Después de revisar los problemas y las teorías de la autonompia de los bancos centrales, estudia la reciente evolución de la banca central latinoamericana en comparación con la europea, destaca los efectos perversos de estas reformas u muestra que sus objetivo es más la estabilidad del sistema financiero que la de los precios. Finalmente, describe las pruebas a que han sido sometidos los nuevos bancos centrales latinomaericanos y los efectos de sus credibilidad. Concluye que estas entidades han tenido que corregir y pagar las incoherencias y los errrores del mercado, y que su 'independencia' o autonomía depende de que sigan cumpliendo con ese papel no sólo por razones económicas o monetarias sino por las necesidades de la democracia política y social.

  14. Distribution of mosquito larvae within the paddy and its implication in larvicidal application in Mwea rice irrigation scheme, Central Kenya.

    Science.gov (United States)

    Mwangangi, Joseph M; Muturi, Ephantus J; Shililu, Josephat I; Jacob, Benjamin; Kabiru, Ephantus W; Mbogo, Charles M; Githure, John I; Novak, Robert J

    2008-03-01

    Distribution of mosquito larvae in inundated rice fields is poorly known despite its profound implications in implementation of vector control programs. Based on oviposition behavior of gravid females and biotic and abiotic conditions of the rice field, distribution of mosquito larvae within the paddy may vary greatly. As a guide to implementation of mosquito vector control program targeting the aquatic stages in the rice fields in Mwea, studies were conducted to determine the distribution of mosquito larvae within the paddy. Twenty-eight cages measuring 50 cm3 were distributed randomly within the paddy during the transplanting stage of the rice growth cycle, and were examined twice per week up to the flowering stage to determine mosquito oviposition pattern. A total of 17,218 mosquito larvae were collected at the periphery and a further 17,570 at the center of the paddy. These comprised 7,461 larvae from the genus Anopheles and 27,327 from genus Culex. The number of pupae collected at the periphery was 1,004 and 1.5 times greater than the number collected at the center. Significantly higher counts of Anopheles larvae were collected at the center (1.00 +/- 0.11) than at the periphery (0.55 +/- 0.05) of the paddy during transplanting stage, but the difference was not significant during the tillering stage. In contrast, significantly higher numbers of Culex larvae were collected from the periphery (3.09 +/- 0.39) than at the center (2.81 +/- 0.24) of the paddy. More pupae were also collected at the center than at the periphery of the paddy. These findings indicate the distribution of Anopheles and Culex larvae in rice fields to be nonrandom; however, for successful achievement of an integrated vector control program targeting the diverse mosquito fauna occurring in rice fields, there is need to target the whole paddy for larvicidal application.

  15. 中心静脉导管在胸腔闭式引流中的应用%Application of central venous catheter to closed thoracic drainage

    Institute of Scientific and Technical Information of China (English)

    梁育梅

    2013-01-01

    Objective:To investigate the effect of application of central venous catheter in closed thoracic drainage instead of chest tube.Methods:60 patients with pneumothorax and pleural effusion were randomly divided into the observation group and the control group (30cases in each group).The patients in the control group were given closed thoracic drainage with common silica gel drainage tube and the central venous catheter was used in the closed thoracic drainage instead of chest tube in the observation group.Results:After 10-day treatment,the indwelling time of catheter and wound healing time were significantly shorter in the observation group than the control group (P < 0.01) ; the incidence of complications was significantly lower in the observation group than the control group (P < 0.05).Conclusion:The central venous catheter used in closed thoracic drainage has the advantages of simple operation,fast healing,less infection,less bleeding and milder pain.The positive nursing care has an important significance to promote the rehabilitation of the patients.%目的:探讨中心静脉导管代替胸管在胸腔闭式引流中的应用效果.方法:将60例气胸、胸腔积液患者随机分为观察组和对照组各30例,对照组采用普通硅胶引流管行胸腔闭式引流术,观察组采用中心静脉导管代胸管行胸腔闭式引流.结果:治疗10 d后,观察组置管时间和伤口愈合时间均明显短于对照组(P<0.01),并发症发生情况明显少于对照组(P<0.05).结论:中心静脉导管应用于胸腔闭式引流术中,操作简单,患者愈合快、感染少、出血少、疼痛轻,积极的护理对促进患者康复具有重要意义.

  16. Studies on the Optimal Supply Model of Two Student Cafeterias with Heterogeneous Rationality%不同理性两学生食堂最优供应模型研究

    Institute of Scientific and Technical Information of China (English)

    亓晓同; 胡军浩

    2014-01-01

    假设两学生食堂具有不同理性(即不同的自我认识),研究其利润、浪费与供应调整系数之间的关系。构造差分方程系统描述就餐人数变化规律,利用生产函数确定食堂的利润,建立不同理性下利润最大和浪费量最小的双目标优化模型。通过数值模拟确定不同理性下最优供应调整系数的取值区间,并对结果进行稳定性分析。%The relationship among the profits, the waste and the supply adjusting coefficient of two student cafete-rias with heterogeneous rationality ( that is, two student cafeterias have self-knowledge) was studied. The variation of the number of meals and the profits was described by difference equations and cost function, and then two-objective op-timization model with the maximizing profits and the minimizing waste was established. The optimal value interval of the supply adjustment coefficient under heterogeneous rationality was determined by numerical simulation. Finally, the stability of the result was analyzed.

  17. Central line infections - hospitals

    Science.gov (United States)

    ... infection; Central venous catheter - infection; CVC - infection; Central venous device - infection; Infection control - central line infection; Nosocomial infection - central line infection; Hospital acquired ...

  18. A cafeteria-rendszer továbbfejlesztésének lehetőségei – múlt, jelen és jövő (Evolution of Flexible Remuneration/Cafeteria Systems – Past, Present and Future)

    OpenAIRE

    Poór, József; László, Gyula; Beke, Jenő; Óhegyi, Katalin; Kolbe, Tamás

    2013-01-01

    A cikkben a szerzők először áttekintik a cafeteria-rendszer legfontosabb jellemzőit (célját, tipikus „stakeholdereit” és HR-stratégiai kérdéseit). Ezt követően megvizsgálják, milyen átalakuláson ment át a béren kívüli juttatások rendszere 1996-tól – az első ilyen rendszerek magyarországi megjelenésétől – napjainkig. Áttekintik azt is, milyen mozgatórugók idézték elő a főbb változásokat, és ezekhez a piaci szereplők hogyan alkalmazkodtak. Szintén vizsgálják a 2012-re vonatkozó legfőbb változás...

  19. 河南省部分农村寄宿制中小学校食堂卫生学评价%Cafeterias hygienic evaluation of rural boarding school of Henan Province

    Institute of Scientific and Technical Information of China (English)

    梁利花; 吴翠平; 娄晓民; 彭玉林; 郭蔚蔚; 李岚

    2011-01-01

    Objective To investigate infrastructure and hygienic situation of rural boarding school cafeterias in Henan province and to explore corresponding solutions for improving the hygienic conditions. Methods Totally 60 boarding schools from each of the three type areas, which included economically developed counties, moderately developed counties and developing counties, were selected and cafeterias conditions of 180 boarding schools were evaluated and analyzed ,which included the facilities and equipment layout conditions, environmental hygiene conditions, food and raw materials procurement, storage and processing situations, employees in health status and cafeteria supervision and management etc. Results The fitting rate of separate functional partition, adequate non-slip on the ground and the "three defenses" facilities in operating rooms was 25. 4%, 20.3% and 19.2%, respectively. The qualified rate of tableware store, special washing facilities, the health permit asked in the procurement of food and raw materials obtained, foodand raw materials standard storage, the remaining food frozen was 37.3%, 44. 1%, 36.7% ,53.1% and 57.6%, respectively. The passing rates of employees health each indicators and several key indlcators of cafeteria supervision and management were above 80%. Conclusion Cafeteria equipments of rural boarding schools are inadequate and the arrangemont is not standard, the procurement, preservation and processing of food and raw materials are lack of standardized, and the supervision and management system put into effect invalidly.%目的 了解河南省农村寄宿制学校食堂的基础设施卫生及食品安全状况,探索存在的问题及相应的解决方案.方法 在经济较发达县、中等发达县及欠发达县各选取60所寄宿制学校,共计180所,对所选学校食堂设施布局及环境卫生,食品及原料采购、贮存及加工,从业人员卫生,食堂监督管理等进行卫生学评价.结果 食堂

  20. Application of Planing Concept “Centralized and Unified” in Heavy Metal Pollution Control%“集中统一”在重金属污染治理规划中的运用

    Institute of Scientific and Technical Information of China (English)

    李水明

    2014-01-01

    The expected effect and significance for application of planing concept “Centralized and Unified” in heavy metal pollution control of Gejiu city .%阐述了“集中统一”规划理念在个旧市重金属污染治理规划中运用的预期效果及借鉴意义。

  1. Joint Applications Pilot of the National Climate Predictions and Projections Platform and the North Central Climate Science Center: Delivering climate projections on regional scales to support adaptation planning

    Science.gov (United States)

    Ray, A. J.; Ojima, D. S.; Morisette, J. T.

    2012-12-01

    The DOI North Central Climate Science Center (NC CSC) and the NOAA/NCAR National Climate Predictions and Projections (NCPP) Platform and have initiated a joint pilot study to collaboratively explore the "best available climate information" to support key land management questions and how to provide this information. NCPP's mission is to support state of the art approaches to develop and deliver comprehensive regional climate information and facilitate its use in decision making and adaptation planning. This presentation will describe the evolving joint pilot as a tangible, real-world demonstration of linkages between climate science, ecosystem science and resource management. Our joint pilot is developing a deliberate, ongoing interaction to prototype how NCPP will work with CSCs to develop and deliver needed climate information products, including translational information to support climate data understanding and use. This pilot also will build capacity in the North Central CSC by working with NCPP to use climate information used as input to ecological modeling. We will discuss lessons to date on developing and delivering needed climate information products based on this strategic partnership. Four projects have been funded to collaborate to incorporate climate information as part of an ecological modeling project, which in turn will address key DOI stakeholder priorities in the region: Riparian Corridors: Projecting climate change effects on cottonwood and willow seed dispersal phenology, flood timing, and seedling recruitment in western riparian forests. Sage Grouse & Habitats: Integrating climate and biological data into land management decision models to assess species and habitat vulnerability Grasslands & Forests: Projecting future effects of land management, natural disturbance, and CO2 on woody encroachment in the Northern Great Plains The value of climate information: Supporting management decisions in the Plains and Prairie Potholes LCC. NCCSC's role in

  2. Application of high-resolution 2D-3C seismic for characterization of the perspective Jurassic shale play in Central Poland

    Science.gov (United States)

    Cyz, M.; Malinowski, M.; Krzywiec, P.; Mulińska, M.; Słonka, Ł.

    2016-10-01

    Here we show the application of broadband (4-120 Hz) 2D-3C seismic for characterization of the perspective Jurassic shale play in Central Poland. Data were acquired along a network of 250 km 2D profiles using single-point, densely spaced receivers (digital 3C sensors) and acquisition was focused on providing both high-resolution and broadband seismic that would enable structural imaging and quantitative interpretation of the key stratigraphic horizons in the Mesozoic sedimentary cover. Such acquisition parameters resulted in good quality data and allowed for more flexibility during processing, e.g., unaliased F-K filtering or digital group forming for ground-roll removal. Processing was oriented to preserve relative amplitudes and the broadband character of the dataset as the input for future quantitative interpretation. We obtained a high-resolution stratigraphic image of the target Upper Jurassic (Upper Kimmeridgian-Tithonian) sequence as well as overall structural portrait of this part of Mid-Polish Trough characterized by strong imprint of the salt tectonics. Lateral continuity of particular stratigraphic sequences has been determined and a more precise structural context for deposition and present-day structure of the Upper Kimmeridgian-Tithonian has been established.

  3. Application of ice thermal storage central air-conditioning technology%冰蓄冷中央空调技术的应用

    Institute of Scientific and Technical Information of China (English)

    仝小鹏

    2011-01-01

    Integrating with the southwest airport refrigeration plant project,it introduces the actual application of ice thermal storage central air-conditioning technology,and respectively expounds the technological principle,structural composition and construction technology of ice thermal storage system.Through economic analysis,it summarizes the merits of ice thermal storage air-conditioning technology,and points out the prospects of the technology,which is worth promoting.%结合西北某机场制冷站工程,介绍了冰蓄冷中央空调技术的实际应用,分别阐述了冰蓄冷系统的工艺原理,结构组成及施工工艺,并通过经济性分析,总结了冰蓄冷中央空调技术的优点,指出该技术前景广阔,值得推广。

  4. Central Solenoid

    CERN Multimedia

    2002-01-01

    The Central Solenoid (CS) is a single layer coil wound internally in a supporting cylinder housed in the cryostat of the Liquid Argon Calorimeter. It was successfully tested at Toshiba in December 2000 and was delivered to CERN in September 2001 ready for integration in the LAr Calorimeter in 2003. An intermediate test of the chimney and proximity cryogenics was successfully performed in June 2002.

  5. Europa central

    Directory of Open Access Journals (Sweden)

    Karel BARTOSEK

    2010-02-01

    Full Text Available La investigación francesa continúa interesándose por Europa Central. Desde luego, hay límites a este interés en el ambiente general de mi nueva patria: en la ignorancia, producto del largo desinterés de Francia por este espacio después de la Segunda Guerra Mundial, y en el comportamiento y la reflexión de la clase política y de los medios de comunicación (una anécdota para ilustrar este ambiente: durante la preparación de nuestro coloquio «Refugiados e inmigrantes de Europa Central en el movimiento antifascista y la Resistencia en Francia, 1933-1945», celebrado en París en octubre de 1986, el problema de la definición fue planteado concreta y «prácticamente». ¡Y hubo entonces un historiador eminente, para quién Alemania no formaría parte de Europa Central!.

  6. Central pain.

    Science.gov (United States)

    Singh, Supreet

    2014-12-01

    Questions from patients about pain conditions and analgesic pharmacotherapy and responses from authors are presented to help educate patients and make them more effective self-advocates. The topic addressed in this issue is central pain, a neuropathic pain syndrome caused by a lesion in the brain or spinal cord that sensitizes one's perception of pain. It is a debilitating condition caused by various diseases such as multiple sclerosis, strokes, spinal cord injuries, or brain tumors. Varied symptoms and the use of pharmacological medicines and nonpharmacological therapies will be addressed.

  7. central t

    Directory of Open Access Journals (Sweden)

    Manuel R. Piña Monarrez

    2007-01-01

    Full Text Available Dado que la Regresión Ridge (RR, es una estimación sesgada que parte de la solución de la regresión de Mínimos Cuadrados (MC, es vital establecer las condiciones para las que la distribución central t de Student que se utiliza en la prueba de hipótesis en MC, sea también aplicable a la regresión RR. La prueba de este importante resultado se presenta en este artículo.

  8. Optimization of process variables by central composite design for the immobilization of urease enzyme on functionalized gold nanoparticles for various applications.

    Science.gov (United States)

    Talat, Mahe; Singh, Ashwani Kumar; Srivastava, O N

    2011-08-01

    In the present study, enzyme urease has been immobilized on amine-functionalized gold nanoparticles (AuNPs). AuNPs were synthesized using natural precursor, i.e., clove extract and amine functionalized through 0.004 M L: -cysteine. Enzyme (urease) was extracted and purified from the vegetable waste, i.e., seeds of pumpkin to apparent homogeneity (sp. activity 353 U/mg protein). FTIR spectroscopy and transmission electron microscopy was used to characterize the immobilized enzyme. The immobilized enzyme exhibited enhanced activity as compared with the enzyme in the solution, especially, at lower enzyme concentration. Based on the evaluation of activity assay of the immobilized enzyme, it was found that the immobilized enzyme was quite stable for about a month and could successfully be used even after eight cycles having enzyme activity of about 47%. In addition to this central composite design (CCD) with the help of MINITAB version 15 Software was utilized to optimize the process variables viz., pH and temperature affecting the enzyme activity upon immobilization on AuNPs. The results predicted by the design were found in good agreement (R2 = 96.38%) with the experimental results indicating the applicability of proposed model. The multiple regression analysis and ANOVA showed the individual and cumulative effect of pH and temperature on enzyme activity indicating that the activity increased with the increase of pH up to 7.5 and temperature 75 °C. The effects of each variables represented by main effect plot, 3D surface plot, isoresponse contour plot and optimized plot were helpful in predicting results by performing a limited set of experiments.

  9. Food safety awareness and behaviors among school cafeteria workers in Henan%中小学食堂从业人员食品安全知识行为调查

    Institute of Scientific and Technical Information of China (English)

    李宏彬; 张昊; 杨汴生; 何健; 张合喜

    2013-01-01

    目的 了解豫北地区中小学校食堂从业人员的食品安全知识知晓情况和卫生行为现状,为规范学校食堂管理和提高服务质量提供依据.方法 分层随机抽取豫北地区61所中小学校食堂从业人员1 236名,进行现场问卷调查,并当场回收.结果 豫北地区中小学食堂从业人员的食品安全知识总体知晓率65.63%,城市学校为69.91%,明显高于农村学校的62.60%(P<0.01).能保持“不留长指甲、不涂指甲油”和“不用裸手拿取直接入口的食品”行为在城市和农村学校所占比例分别为98.82%,97.65%和95.18%,96.69%;“不将个人衣物及私人物品带入食品处理区”行为的比例较低,城市和农村分别为78.82%,73.83%.结论 中小学校食堂从业人员的食品安全知识和行为水平有待进一步提高,尤其应加强农村学校食堂从业人员食品卫生知识培训.%Objective To investigate food safety awareness and behaviours among school cafeteria staffs in Henan for the improvement of supervision and service quality.Methods A questionnaire survey was conducted among 1 236 school cafeteria staffs chosen through stratified and cluster randomization sampling in 61 elementary and junior schools.Results The awareness rate of food safety was 65.63%.The awareness rate among urban staff (69.91%) was significantly higher than that of rural areas (62.63%).Proportions of staff that kept fingernails short,unpolished,and clean and never touched any food by hands in urban and rural schools were 98.82%,97.65%,95.18% and 96.69%,respectively.However,the proportion of staff that never carried personal belongings into food processing areas were quite low both in urban and rural schools (78.82% and 73.83%).Conclusion The food safety awareness and related healthy behaviors among school cafeteria staff should be further improved.Meanwhile,the supervision system of school cafeteria should also be strengthened

  10. Application of six sigma to reloads design of the Laguna Verde Central with length until 17 days; Aplicacion de seis sigma para disenar recargas de la Central Laguna Verde con duracion hasta de 17 dias

    Energy Technology Data Exchange (ETDEWEB)

    Espinosa G, J.M. [Comision Federal de Electricidad, Central Laguna Verde, Subgerencia General de Operacion, Planeacion, Veracruz (Mexico)]. e-mail: mespinos@cfe.gob.mx

    2007-07-01

    The more important value in the Laguna Verde Central it is the safety. The international experience it confirms us that the more safe plants its are those more productive, this conclusion and reasoning indicate to the power station that we are in the correct road, improving the acting we will obtain that greater interest for us in the Laguna Verde Central (to increase the safety) and as added value to be able to be one of the best business for the Federal Commission of Electricity. With a future vision and commitment of high acting was integrated in an external place to all the area headquarters: (Maintenance, Planning, Operation, Parts of Reserve, Finances, Contracts, Supplies, Warehouse, design Engineering, place Engineering, engineering of systems, radiological Protection, etc.) to carry out a combined work with the unique challenge of drifting with the biggest level detail the program of a recharge and certainly to get ready to achieve their execution (all this without omitting any consideration for smaller or simpler than it seemed), looking for high quality in the works, with and bigger level of safety, with the minimum possible dose, the more reasonable cost and considering a new concept of human character, to achieve the above-mentioned without the participant personnel's stress, with the premise that a good plan and commitment of all the only one that it can bring us as result it is the success of the whole organization. (Author)

  11. [Central anticholinergic syndrome].

    Science.gov (United States)

    Fernández Urretavizcaya, P; Cenoz Osinaga, J C; Jáuregui Garía, M L; Gállego Culleré, J

    1991-10-01

    Two new cases of anticolinergic central syndrome are described. The first case, a 8 year old girl, suffered a severe encefalopathy after topical application of mydriatic cholirio as an aid in a rutine study of ocular refraction. The second case, 67 year old man presented a severe neurological picture after accidental intake of a silvester plantground (Atropa belladonna). His neurological condition returned quickly to normal whith administration of physostigmine. Differents aspects of the etiology, clinical picture and diagnosis are discussed with special emphasis in patients with delirium or acute confusional states. Finally, attention is drawn in the necessity of a properly use of anticholinergic drugs overcoat in aged or children.

  12. Effects of farmers' practices of fertilizer application and land use types on subsequent maize yield and nutrient uptake in central Benin

    NARCIS (Netherlands)

    Saidou, A.; Kossou, D.; Acakpo, K.; Richards, P.; Kuyper, T.W.

    2012-01-01

    Four on-farm experiments in central Benin examined whether land-use succession and fertilizer treatments for prior cotton would sustain subsequent maize crop yields and achieve balanced plant nutrition. Treatments consisted of three prior land use successions, i.e. before planting maize (egusi melon

  13. Application of the Central Limit Theorem in microbial risk assessment: High number of serving reduces the Coefficient of Variation of food-borne burden-of-illness

    NARCIS (Netherlands)

    Pérez-Rodríguez, F.; Zwietering, M.H.

    2012-01-01

    The Central Limit Theorem (CLT) is proposed as a means of understanding microbial risk in foods from a Public Health perspective. One variant of the CLT states that as the number of random variables, each with a finite mean and variance, increases (¿8), the distribution of the sum (or mean) of those

  14. Detection of Ca2+-dependent acid phosphatase activity identifies neuronal integrity in damaged rat central nervous system after application of bacterial melanin

    Directory of Open Access Journals (Sweden)

    Tigran R Petrosyan

    2016-01-01

    Full Text Available The study aims to confirm the neuroregenerative effects of bacterial melanin (BM on central nervous system injury using a special staining method based on the detection of Ca2+-dependent acid phosphatase activity. Twenty-four rats were randomly assigned to undergo either unilateral destruction of sensorimotor cortex (group I; n = 12 or unilateral rubrospinal tract transection at the cervical level (C3–4 (group II; n = 12. In each group, six rats were randomly selected after surgery to undergo intramuscular injection of BM solution (BM subgroup and the remaining six rats were intramuscularly injected with saline (saline subgroup. Neurological testing confirmed that BM accelerated the recovery of motor function in rats from both BM and saline subgroups. Two months after surgery, Ca2+-dependent acid phosphatase activity detection in combination with Chilingarian's calcium adenoside triphosphate method revealed that BM stimulated the sprouting of fibers and dilated the capillaries in the brain and spinal cord. These results suggest that BM can promote the recovery of motor function of rats with central nervous system injury; and detection of Ca2+-dependent acid phosphatase activity is a fast and easy method used to study the regeneration-promoting effects of BM on the injured central nervous system.

  15. 中心静脉导管合理应用的研究进展%The research progress of the reasonable application of central venous catheter

    Institute of Scientific and Technical Information of China (English)

    王雅杰; 黄抱娣; 王玲; 吕小林; 卞文霞

    2015-01-01

    With the continuous development of intravenous fluids tools, a central venous catheter (CVC), percutaneous puncture via peripheral central venous catheter (PICC) placement, fully implantable venous infusion port of central venous catheter (TIVAP) and so on. How people choose the venous catheter due to illness, is often face problems in nursing work. In this paper, various of catheter is made in this paper.%随着静脉输液工具的不断发展,出现了经皮穿刺中心静脉导管(CVC)、经外周置入中心静脉导管(PICC)、完全植入式静脉输液港(TIVAP)等中心静脉导管。如何因人因病合理选择静脉导管是护理工作中经常面临的问题。本文就各种导管的特点做了综述。

  16. Application and nursing of central venous catheter in Intensive Care Unit%中心静脉置管在ICU的应用及护理

    Institute of Scientific and Technical Information of China (English)

    赵斯芹

    2012-01-01

    Objective To investigate the nursing measures for patients who use central venous catheter in Intensive Care Unit (ICU). Methods A retrospective analysis of 204 patients with central venous catheter was conducted. Results After treatment,successful extubation was seen in 177 cases,blocked tubes 8 cases,catheter- related infection in 5 cases,catheter withdrawal in 3 cases and catheter displacement 11 cases. Conclusion According to the causes of complications of central venous catheter,timely and appropriate nursing measures can reduce or avoid such complications.%目的 探讨中心静脉置管期的护理措施.方法 对204例中心静脉置管患者进行回顾性分析.结果 治疗完毕顺利拔管177例,导管堵塞8例,导管相关感染5例,导管脱出3例,移位11例.结论 根据中心静脉置管发生并发症的原因,及时采取相应的护理措施,可以减少或避免并发症的发生.

  17. Development of a methodology for the economical analysis of fuel cycles, application to the Laguna Verde central; Desarrollo de una metodologia para el analisis economico de ciclos de combustible, aplicacion a la Central Laguna Verde

    Energy Technology Data Exchange (ETDEWEB)

    Malfavon, S.M.; Trejo, M.G.; Hernandez, H. [FI-UNAM, 04500 Mexico D.F. (Mexico); Francois, J.L.; Ortega, R.F. [FI-UNAM, Paseo Cuauhnahuac 8532, Jiutepec, Morelos (Mexico)

    2003-07-01

    In this work a methodology developed to carry out the economical analysis of the fuel cycle of a nuclear reactor is presented. The methodology was applied to the Laguna Verde Nuclear Power Station (CNLV). The design of the reload scenarios of the CNLV are made with the Core Master Presto code (CM-Presto), three-dimensional simulator of the reactor core, the launched data by this, as well as the information of the Energy use plan (PUE), it allowed us to obtain reliable results through the fitness of an algorithm of economic calculation that considers all the components of the fuel cycle to present worth. With the application of the methodology it was obtained the generated energy, as well as their respective cost of each sub lot type of assemblies by operation cycle, from the start-up of the CNLV until September 13, 2002. Using the present worth method its were moved all the values at November 5, 1988, date of operation beginning. To the final of the analysis an even cost of 6.188 mills/kWh was obtained for those first 9 cycles of the Unit 1 of the CNLV, being observed that the costs of those first 3 operation cycles are the more elevated. Considering only the values starting from the cycle 4, the levelled cost turns out to be of 5.96 mills/kWh. It was also obtained the cost by fuel lot to evaluate the performance of assemble with the same physical composition. (Author)

  18. Central Puget Sound Ecopath/Ecosim model biological parameters - Developing food web models for ecosystem-based management applications in Puget Sound

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This project is developing food web models for ecosystem-based management applications in Puget Sound. It is primarily being done by NMFS FTEs and contractors, in...

  19. Central Puget Sound Ecopath/Ecosim model outputs - Developing food web models for ecosystem-based management applications in Puget Sound

    Data.gov (United States)

    National Oceanic and Atmospheric Administration, Department of Commerce — This project is developing food web models for ecosystem-based management applications in Puget Sound. It is primarily being done by NMFS FTEs and contractors, in...

  20. The role of central, regional and local administrations in the application of the Kyoto protocol in the forestry sector in Italy

    Directory of Open Access Journals (Sweden)

    Pompei E

    2007-01-01

    Full Text Available According to art. 3.3 and 3.4 of the Kyoto Protocol and subsequent UNFCCC COP's and national decisions, Italy shall report the net changes in GHG emissions by sources and removals by sinks resulting from afforestation, reforestation and deforestation (art. 3.3 and forest management (art. 3.4 activities. To assess art. 3.3 activities, Italy will define methods to estimate land use changes occurring after 31 December 1989. The paper considers the key-role that central administration shall have, as well as the role of regional and local administrations in order to solve some specific topics regarding data collection and management issues.

  1. 液压式套管扶正器在侧钻水平井中的应用%Application of hydraulic casing centralizer in sidetracked horizontal well drilling

    Institute of Scientific and Technical Information of China (English)

    尹方雷; 白冬青; 龚建凯; 徐肇国; 于子涵; 夏进军

    2013-01-01

      常规侧钻水平井造斜段及水平段完井管柱居中困难,导致固井水泥环厚度不均,质量较差,易发生出水、出砂等问题,进而致使侧钻水平井生产寿命较短,严重影响了单井产量。现场多使用扶正器来提高套管居中度,但是常规扶正器存在扶正效果差、破坏井壁等问题,为此研制了液压式套管扶正器。该工具原始外径小、下入安全,膨胀后外径大、扶正能力强,能够极大地提高侧钻水平井完井管柱的居中程度,改善固井质量,延长侧钻水平井的生产寿命。该类扶正器现场应用简便,不影响正常的施工程序,在辽河和冀东油田进行了多口井的现场应用,效果显著。%When drilling the buildup section and horizontal section of conventional sidetracked horizontal wells, the drilling tools are difficult to be centralized, leading to uneven cement thickness, and poor cementing quality, resulting in water and sand production. The problem would lead to low production rate and short service time of sidetracked wells. In field application, centralizer is commonly used to improve the casing centralizing degree, but conventional centralizer has poor centralizing effect and would break wellbore. Therefore, a type of Hydraulic casing centralizer was developed. The tool has small original outer diameter, safe tripping process, large expended outer diameter, and great uprighting capacity, so it can greatly improve the centralizing degress of the completion string of sidetracked horizontal wells. Furthermore, the technique can improve cementing quality, enlarge service time of sidetracked horizontal wells, and increase production rate and economical effect. The tools are simple being applied in field, with no passive effect on normal drilling process

  2. Estimating current and future streamflow characteristics at ungaged sites, central and eastern Montana, with application to evaluating effects of climate change on fish populations

    Science.gov (United States)

    Sando, Roy; Chase, Katherine J.

    2017-03-23

    A common statistical procedure for estimating streamflow statistics at ungaged locations is to develop a relational model between streamflow and drainage basin characteristics at gaged locations using least squares regression analysis; however, least squares regression methods are parametric and make constraining assumptions about the data distribution. The random forest regression method provides an alternative nonparametric method for estimating streamflow characteristics at ungaged sites and requires that the data meet fewer statistical conditions than least squares regression methods.Random forest regression analysis was used to develop predictive models for 89 streamflow characteristics using Precipitation-Runoff Modeling System simulated streamflow data and drainage basin characteristics at 179 sites in central and eastern Montana. The predictive models were developed from streamflow data simulated for current (baseline, water years 1982–99) conditions and three future periods (water years 2021–38, 2046–63, and 2071–88) under three different climate-change scenarios. These predictive models were then used to predict streamflow characteristics for baseline conditions and three future periods at 1,707 fish sampling sites in central and eastern Montana. The average root mean square error for all predictive models was about 50 percent. When streamflow predictions at 23 fish sampling sites were compared to nearby locations with simulated data, the mean relative percent difference was about 43 percent. When predictions were compared to streamflow data recorded at 21 U.S. Geological Survey streamflow-gaging stations outside of the calibration basins, the average mean absolute percent error was about 73 percent.

  3. Temporary Central Venous Catheter in Hemodialysis Application and Nursing%临时性中心静脉留置管在血液透析中应用与护理

    Institute of Scientific and Technical Information of China (English)

    余艳红

    2014-01-01

    目的探讨并分析临时性中心静脉留置管在血液透析中应用以及护理。方法回顾性分析我院自2010年12月~2013年12月所收治的60例血液透析患者中心静脉置管情况以及有关护理。结果60例血液透析患者中有2例患者由于置管并发症的发生而拔管。结论正确、安全且有效地应用以及维护中心静脉置管,同时采取合理的护理方式是预防各种并发症发生以及延长置管使用寿命的一个关键。%Objective To investigate and analyze the application of indwel ing catheter in hemodialysis and nursing of temporary central venous. Methods Retrospective analysis of our hospital from 2010 December~2013 year in December the hospital treated 60 cases of hemodialysis patients with central venous catheter and nursing care. Results 60 cases of hemodialysis patients in 2 cases of patients with complications of catheterization occurred and extubation. Conclusion Correct, safe and ef ective application and maintenance of central venous catheter, while taking care to prevent al kinds of complications is reasonable and the extension of a key tube service life.

  4. Central bank Financial Independence

    OpenAIRE

    J.Ramon Martinez-Resano

    2004-01-01

    Central bank independence is a multifaceted institutional design. The financial component has been seldom analysed. This paper intends to set a comprehensive conceptual background for central bank financial independence. Quite often central banks are modelled as robot like maximizers of some goal. This perspective neglects the fact that central bank functions are inevitably deployed on its balance sheet and have effects on its income statement. A financially independent central bank exhibits ...

  5. 中心静脉导管腹腔置入的应用观察%Application and observation of placing central venous catheter into abdominal cavity

    Institute of Scientific and Technical Information of China (English)

    张玉军; 于建昌; 徐光耀

    2012-01-01

    Objective To observe the feasibility and the clinical effect of placing central venous catheter into the abdominal cavity. Methods 46 patients with massive ascites were randomly divided into two groups: group A and group B, 23 cases in each group, The patients in group A were placed central venous catheter into abdominal cavity. Group B was the traditional abdominal puncture's group. Results The central venous catheter was inserted into the abdominal cavity of patients in group A, each patient's average abdominal puncture was (l.l±0.1) times, average accumulative total put liquid was (18 210+65) mL,average note medicine was (1.5±0.2) times the number, clinical symptoms improved 21 cases,the recovery was 91.3%. Group B give repeated technic of abdominal smoke fluid, each patient's average abdominal puncture was (3.3± 0.2) times, average accumulative total put liquid was (9 750±70) mL, the mean number of injcetion was (0.7±0.1) times, clinical symptoms of 16 cases improved, the recovery rate was 69.6%. There were significant differences between the two groups with puncture number, releasing ascites, injecting the drugs into abdominal cavity, improving clinical symptoms (P < 0.05). Group A was better than group B. Conclusion The techniques of placing central venous catheter into the abdominal cavity has simple operation, good effect in releasing ascites and injecting the drugs into abdominal cavity, few side effect and should be used in massive ascites.%目的 观察中心静脉导管腹腔置入的可行性及临床应用效果.方法 将大量腹水的46例患者随机分为A、B两组,每组23例,A组为中心静脉导管腹腔置入组,B组为传统的腹腔穿刺术组.结果 A组把中心静脉导管置入腹腔,每例患者平均腹腔穿刺(1.1±0.1)次,平均累计放液(18 210±65)mL,平均注药次数(1.5±0.2)次,临床症状好转21例,好转率为91.3%.B组给予反复腹腔穿刺术抽液,每例患者平均穿刺次数(3.3±0.2)

  6. Instabilities of MHD Waves Produced by Coupling of Rotation and Gradient of Magnetic Field and its Possible Application in the Galactic Central Region

    CERN Document Server

    Das, Ipsita

    2008-01-01

    An analysis of MHD wave propagating in a gravitating and rotating medium permeated by non-uniform magnetic field has been done. It has been found that the Gradient of Magnetic Field when coupled with Rotation becomes capable to generate few instabilities (Temporal or Spatial) leading to the damping or amplification of MHD waves. The Jean's criterion is not sufficient for stability always. Rather, the waves will suffer instability unless their wave length (frequency) is less (greater) than certain critical values. Otherwise, those will smoothly propagate outward. Out of different scenarioes depending on the direction of the magnetic field, its gradient, rotation and wave propagation three important Special Cases have been discussed and different stability criteria have been derived. Finally, using the above theory we have obtained the stability/instability criteria for the waves moving parallel and perpendicular to the galactic plane in the Core and Periphery of the Central Region of Galaxy (C.R.G.) due to the...

  7. Integrated application of gravity and seismic methods for determining the dip angle of a fault plane: Case of Mahjouba fault (Central Tunisian Atlas Province, North Africa)

    Science.gov (United States)

    Gabtni, H.; Hajji, O.; Jallouli, C.

    2016-07-01

    A procedure for a dip angle determination of a fault plane from gravity field data is presented to constrain a seismic profile interpretation. This procedure is applied on Mahjouba normal fault at the western border of Kalaa Khesba graben (Central Tunisian Atlas Province, North Africa). Seismic and detailed gravity data, in this region, were analyzed to provide more constraints on the geometry of the fault dip angle. The Mahjouba fault is mapped as three major parallel lineaments extended for 2 km with a NW-SE to N-S trend. The dip of the Mahjouba fault is estimated from the gravity modeling data to be 45°E. This study reveals that integrating gravity and seismic data provides accurate mapping of faults geometry and such result provides useful information and constraints on the exploration of natural resources.

  8. Computed tomography morphometric analysis of the central clival depression and petroclival angle for application of the presigmoid approach in the pediatric population

    Directory of Open Access Journals (Sweden)

    Sohum K Desai

    2016-01-01

    Full Text Available Aims: Lateral transtemporal approaches are useful for addressing lesions located ventral to the brainstem, especially when the pathologic diagnosis of the tumor dictates that a gross or near total resection improves outcomes. One approach, the presigmoid approach receives little attention in the pediatric population thus far. We sought to characterize morphometric changes, particularly the clival depth and the petroclival Cobb angle, that occur in the temporal bones of children and draw implications about doing a presigmoid approach in children. Settings and Design: This study was a retrospective study performed at John Sealy Hospital, a level-one trauma center that takes care of pediatric injuries as well. Subjects and Methods: We performed a morphometric analysis of noncontrast computed tomography head studies in 96 boys and 67 girls. Central clival depth and petroclival angle were obtained in the axial plane at the level of the internal auditory meatus using the method described by Abdel Aziz et al. Statistical Analysis Used: Descriptive statistics and Student′s t-test to compare groups were calculated using Microsoft Excel. Results: We found no gender difference in mean central clival depth or petroclival angle (P = 0.98 and P = 0.61, respectively. However, when we broke our cohort by age into those younger than 9 years of age and those 10 years or older, we found the petroclival angle decreased by 6.2° which was statistically significant (P < 0.000000006. Conclusions: These findings suggest that a presigmoid retrolabyrinthine approach is useful for children 9 years of age and younger as the petroclival angle appears to decrease resulting in a shallower clival depression in these patients.

  9. Application of ultrasound differential diagnosis in abnormalities of fetus central nerve system%超声鉴别诊断技术在胎儿中枢神经系统畸形诊断中的应用

    Institute of Scientific and Technical Information of China (English)

    邓学东; 李红; 梁青; 常红梅; 姜小力; 唐亚奇; 梁泓; 冯鸿; 陆伟

    2011-01-01

    Objective To improve the clinical application of ultrasound differential diagnosis in abnormalities of fetus central nerve system. Methods Ultrasound imaging features in 217 cases of abnormalities in central nerve system confirmed by autopsy or follow-up were analyzed retrospectively. Results A total of 217 cases of anomaly in the central never system were examined prenatally by ultrasound and each showed typical imaging feature. Among these cases , there were 45 cases of anencephaly, 4 cases of hydranencephaly, 5 cases of arachnoid' s cyst, 2 cases of aneurysm of the vein of Galen, 78 cases of ventriculomegaly ( among them 46 cases of aqueduct stenosis), 13 cases of cephalocele, 17 cases of Dandy-Walker complex, 23 cases of spina bifida, 9 cases of holoprosencephaly, 5 cases of agenesis of the corpus callosum,8 cases of sacrococcygeal teratoma and 8 cases of choroid plexus cysts.Conclusion Application of ultrasound differential diagnosis by ultrasound for detection of abnormalities in fetus central nerve system( i. e. three sections and 12clues ), is extremely important.%目的 探讨产前超声鉴别诊断技术在胎儿中枢神经系统畸形诊断中的应用.方法 对经随访或引产证实217例中枢神经系统畸形的声像图特征进行回顾性分析.结果 产前超声诊断217例胎儿中枢神经系统畸形,其中无脑儿45例、水脑畸形4例、蛛网膜囊肿5例、Galen静脉瘤2例、脑室扩张78例(其中46例是中脑导水管狭窄)、脑膨出13例、Dandy-Walker综合征17例、开放性脊柱裂23例、前脑无裂畸形9例、胼胝体缺失5例、骶尾部畸胎瘤8例、脉络丛囊肿8例.结论 掌握超声检查胎儿中枢神经系统畸形的鉴别诊断技术,即三个切面和12种分析思路,对产前超声检查极为重要.

  10. Deconstruction of the asbestos cement roof of the central market in Alicante difficulties in the practical application of RD 396/2006 (works with risk of exposure to asbestos); Deconstruccion de la cubierta de asbesto-cemento del Mercado Central de Abastos de Alicante. Dificultades en la aplicacion practica del RD 396/2006 (trabajos con riesgo de exposicion al amianto)

    Energy Technology Data Exchange (ETDEWEB)

    Sirvent Perez, C. D.

    2010-07-01

    The project and the works described below mainly deal with the deconstruction of the current asbestos-cement roof of the Central Market in Alicante in order to replace it with another roof of zinc diamond scales, similar to the original which was implementation in 1921 when the building went into service. These works were necessary to avoid the causes (and consequences) that generate the appearance of rainwater infiltration, as was described in an earlier report that was done in 2006, also drafted by the undersigned technicians. The article shows the difficulty of the practical application of RD 396/2006 (minimum health and safety requirements for works with risks of exposure to asbestos) in a case of a certain complexity such as this, especially in areas such as economic (rising costs), technical (increasing difficulty of implementation), and the total duration of the work (total time extension due to interference with other trades). (Author) 14 refs.

  11. Central station market development strategies for photovoltaics

    Science.gov (United States)

    1980-01-01

    Federal market development strategies designed to accelerate the market penetration of central station applications of photovoltaic energy system are analyzed. Since no specific goals were set for the commercialization of central station applications, strategic principles are explored which, when coupled with specific objectives for central stations, can produce a market development implementation plan. The study includes (1) background information on the National Photovoltaic Program, photovoltaic technology, and central stations; (2) a brief market assessment; (3) a discussion of the viewpoints of the electric utility industry with respect to solar energy; (4) a discussion of commercialization issues; and (5) strategy principles. It is recommended that a set of specific goals and objectives be defined for the photovoltaic central station program, and that these goals and objectives evolve into an implementation plan that identifies the appropriate federal role.

  12. Systems with centralized ventilation. Examples and applications. Air conditioning with regard to VDI 3804; Systeme mit zentraler Lueftung. Beispiele und Anwendungen. Raumklimatisierung nach VDI 3804

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2013-06-15

    Well coordinated, holistically designed ventilation and air-conditioning systems in the commercial sector increasingly gain in importance. Engineers and technicians have now to choose from a seemingly immense variety of available components. A good planning assistance and decision support are provided by the revised VDI guideline 3804 which describes six system combinations and thus defines the state of the art in this scope of application.

  13. Coverage centralities for temporal networks*

    Science.gov (United States)

    Takaguchi, Taro; Yano, Yosuke; Yoshida, Yuichi

    2016-02-01

    Structure of real networked systems, such as social relationship, can be modeled as temporal networks in which each edge appears only at the prescribed time. Understanding the structure of temporal networks requires quantifying the importance of a temporal vertex, which is a pair of vertex index and time. In this paper, we define two centrality measures of a temporal vertex based on the fastest temporal paths which use the temporal vertex. The definition is free from parameters and robust against the change in time scale on which we focus. In addition, we can efficiently compute these centrality values for all temporal vertices. Using the two centrality measures, we reveal that distributions of these centrality values of real-world temporal networks are heterogeneous. For various datasets, we also demonstrate that a majority of the highly central temporal vertices are located within a narrow time window around a particular time. In other words, there is a bottleneck time at which most information sent in the temporal network passes through a small number of temporal vertices, which suggests an important role of these temporal vertices in spreading phenomena. Contribution to the Topical Issue "Temporal Network Theory and Applications", edited by Petter Holme.Supplementary material in the form of one pdf file available from the Journal web page at http://dx.doi.org/10.1140/epjb/e2016-60498-7

  14. Targeted Next-Generation Sequencing in Molecular Subtyping of Lower-Grade Diffuse Gliomas: Application of the World Health Organization's 2016 Revised Criteria for Central Nervous System Tumors.

    Science.gov (United States)

    Carter, Jamal H; McNulty, Samantha N; Cimino, Patrick J; Cottrell, Catherine E; Heusel, Jonathan W; Vigh-Conrad, Katinka A; Duncavage, Eric J

    2017-03-01

    The 2007 World Health Organization Classification of Tumours of the Central Nervous System classifies lower-grade gliomas [LGGs (grades II to III diffuse gliomas)] morphologically as astrocytomas or oligodendrogliomas, and tumors with unclear ambiguous morphology as oligoastrocytomas. The World Health Organization's newly released (2016) classification incorporates molecular data. A single, targeted next-generation sequencing (NGS) panel was used for detecting single-nucleotide variation and copy number variation in 50 LGG cases originally classified using the 2007 criteria, including 36 oligoastrocytomas, 11 oligodendrogliomas, 2 astrocytomas, and 1 LGG not otherwise specified. NGS results were compared with those from IHC analysis and fluorescence in situ hybridization to assess concordance and to categorize the tumors according to the 2016 criteria. NGS results were concordant with those from IHC analysis in all cases. In 3 cases, NGS was superior to fluorescence in situ hybridization in distinguishing segmental chromosomal losses from whole-arm deletions. The NGS approach was effective in reclassifying 36 oligoastrocytomas as 30 astrocytomas (20 IDH1/2 mutant and 10 IDH1/2 wild type) and 6 oligodendrogliomas, and 1 oligodendroglioma as an astrocytoma (IDH1/2 mutant). Here we show that a single, targeted NGS assay can serve as the sole testing modality for categorizing LGG according to the World Health Organization's 2016 diagnostic scheme. This modality affords greater accuracy and efficiency while reducing specimen tissue requirements compared with multimodal approaches.

  15. 抗感染中心静脉导管临床应用的研究%Effect of clinical application of anti-infective central venous catheter

    Institute of Scientific and Technical Information of China (English)

    谢明英; 申建维; 刘显畅

    2014-01-01

    目的:探讨抗感染中心静脉导管在减少导管相关性感染和细菌定植中的作用,以降低导管相关感染率。方法选取2011年5月-2013年5月于IC U行深静脉置管患者64例,随机分为观察组和对照组,各32例,对照组采用普通中心静脉导管,观察组采用黄嘧啶银和氯己定抗感染中心静脉导管,观察比较两组患者导管留置、导管拔除、导管相关性感染和细菌定植。结果留置导管时间观察组为(14.5±2.6)d,对照组为(8.3±3.7)d,观察组留置导管时间长于对照组,两组比较差异有统计学意义(χ2=6.563,P<0.05),观察组无局部感染,对照组局部感染6例感染率18.75%,观察组局部感染、导管细菌定植例数明显少于对照组,两组比较差异有统计学意义(P<0.05);观察组细菌定植和感染延时显著优于对照组,差异有统计学意义(P<0.001)。结论抗感染中心静脉导管在减少导管相关性感染和细菌定植中具有重要的积极作用,但导管留置时间>两周,抗感染中心静脉导管的细菌定植和导管相关性感染明显增加,通过缩短导管留置时间是减少导管相关性感染的重要手段。%OBJECTIVE To explore the effect of use of anti-infective central venous catheter on reduction of incidence of catheter-related infections or bacterial colonization so as to reduce the incidence of catheter-related infections .METHODS Totally 64 patients who underwent the deep venous catheterization in the ICU from May 2011 to May 2013 were enrolled in the study and randomly divided into the observation group and the control group ,with 32 cases in each group ,the control group was treated with conventional central venous catheter ,while the observation group was given yellow-Ag and chlorhexidine anti-infective central venous catheter ; the intubation ,extubation , catheter-associated infections , and bacterial

  16. Development and application of a fecal antigen diagnostic sandwich ELISA for estimating prevalence of Fasciola gigantica in cattle in central Java, Indonesia.

    Science.gov (United States)

    Estuningsih, Endah; Spithill, Terry; Raadsma, Herman; Law, Ruby; Adiwinata, G; Meeusen, Els; Piedrafita, David

    2009-04-01

    The purpose of this study was to compare the sensitivity and specificity of an ELISA test to detect Fasciola gigantica antigens (coproantigens) in bovine feces, with fecal egg counting and an ELISA for detecting anti-F. gigantica antibodies in serum. Monoclonal antibodies to cathepsin L were generated and used to capture this antigen in feces of infected cattle. Blood, feces, and livers were collected from 150 cattle at an abattoir in Jakarta, Indonesia, for anti-Fasciola antibodies, coproantigen detection, and F. gigantica egg and worm counts. Fluke recovery varied from 1 to 426 per host, with a mean of 32 flukes. The results showed that the sensitivity and specificity of coproantigen detecting ELISA (95 and 91%, respectively) was better than the anti-F. gigantica antibody ELISA (91 and 88%, respectively) and to fecal egg counting (87 and 100%, respectively). The coproantigen ELISA was able to detect 100% of the cattle with >15 flukes. A survey of 305 cattle in central Java over a 10-mo period validated this test in the field, demonstrating a high prevalence of fascioliasis and establishing the test as a useful diagnostic method to determine patent F. gigantica infections in cattle.

  17. The application of terrestrial laser scanner and photogrammetry in measuring erosion and deposition processes in humid badlands in the Central Spanish Pyrenees

    Science.gov (United States)

    Nadal-Romero, E.; Revuelto, J.; Errea, P.; López-Moreno, J. I.

    2015-04-01

    Erosion and deposition processes in badland areas are usually estimated using traditional observations of topographic changes, measured by erosion pins or profile meters (invasive techniques). In recent times, geomatic techniques (non-invasive) have been routinely applied in geomorphology studies, especially in erosion studies. These techniques provide the opportunity to build high-resolution topographic models at subcentimeter accuracy. By comparing different 3-D point clouds of the same area, obtained at different time intervals, the variations in the terrain and temporal dynamics can be analyzed. The aim of this study is to assess and compare the functioning of Terrestrial Laser Scanner (TLS, RIEGL LPM-321) and close range photogrammetry techniques (Camera FUJIFILM, Finepix x100 and Software PhotoScan by AgiSoft), to evaluate erosion and deposition processes in a humid badland area in the Central Spanish Pyrenees. Results show that TLS data sets and photogrammetry techniques provide new opportunities in geomorphological erosion studies. The data we recorded over one year demonstrated that north-facing slopes experienced more intense and faster changing geomorphological dynamics than south-facing slopes as well as the highest erosion rates. Different seasonal processes were observed, with the highest topographic differences observed during winter periods and the high intensity rainfalls in summer. While TLS provided the highest resolution models, photogrammetry was still a faster methodology in the field and precise at short distances. Both techniques do not require direct contact with the soil and thus prevent the usual surface disturbance of traditional and invasive methods.

  18. Application of the Central Limit Theorem in microbial risk assessment: high number of servings reduces the Coefficient of Variation of food-borne burden-of-illness.

    Science.gov (United States)

    Pérez-Rodríguez, Fernando; Zwietering, Marcel H

    2012-02-15

    The Central Limit Theorem (CLT) is proposed as a means of understanding microbial risk in foods from a Public Health perspective. One variant of the CLT states that as the number of random variables, each with a finite mean and variance, increases (→∞), the distribution of the sum (or mean) of those variables approximates a normal distribution. On the basis of the CLT, the hypothesis introduced by this paper states that the Coefficient of Variation (CV) of the annual number of food-borne illness cases decreases as a result of a larger number of exposures (or servings) (n). Second-order Monte-Carlo analysis and classical statistics were used to support the hypothesis, based on existing risk models on Listeria monocytogenes in deli meat products focused on elderly people in the United States. Likewise, the hypothesis was tested on epidemiological data of annual incidence of salmonellosis and listeriosis in different countries (i.e. different n). Although different sources of error affected the accuracy of the results, both the Monte-Carlo analysis (in silico) and epidemiological data (in vivo), especially for salmonellosis, demonstrated that the CV of the annual number of cases decreased as n increased as stated by the CLT. Furthermore, results from this work showed that classical statistical methods can be helpful to provide reliable risk estimates based on simple and well-established statistical principles.

  19. Application of central air conditioner system on modular drilling rig of offshore ifxed platform%集中空调系统在海洋固定平台模块钻机上的应用研究

    Institute of Scientific and Technical Information of China (English)

    罗立臣; 许瑞杰; 马冬辉

    2014-01-01

    Based on the air conditioner selection of Lu Feng7-2 oil ifeld modular drilling rig project, this paper determines two sets of selection of air conditioner by preliminary study, which are central and separation air conditioner systems, respectively. With comparison between the central air conditioner and the split air conditioner in cost, effciency, comfort, space, etc., it concludes that the central air conditioner system has the advantages of lower operation cost, higher energy effciency ratio, better comfort capability, smaller space occupation and so on. It also analyzes its superiority and prospect of application on the modular drilling rig of offshore ifxed platform, which can provide a certain reference for the room cooling design and the equipment selection.%结合陆丰7-2油田模块钻机项目空调选型,通过前期调查研究制定了两套空调选型方案:集中空调系统方案和分体空调系统方案。通过对比两者在费用、工作效率、舒适性、占用空间等方面的特点,得出集中空调系统具有初始投入及运行成本低、能效比高、舒适性好、占地面积小等方面的优点,并分析了集中空调在海洋固定平台模块钻机上使用的优越性以及应用前景,对海洋固定平台模块钻机的房间制冷设计及设备选型提供了一定的参考。

  20. 国库集中支付制度在高等院校实行的问题和建议%The Application of Centralized Treasury Payment System (CTPS) in Universities and Colleges

    Institute of Scientific and Technical Information of China (English)

    张弛

    2011-01-01

    2010年9月26日,财政部下发了财库[2010]104号《中央单位教育收费收缴管理暂行办法》的通知通知中对教育收费收缴工作作了具体要求。国库集中支付是目前财政管理制度改革的一项重要内容,在高校实施国库集中支付制度,对高校的预算管理、财务管理、会计核算产生了深刻的影响。文章将国库集中支付制度与通知相结合论述了这项制度在高校具体实施过程中所引发的问题,并对此提出意见和建议。%In September 26, 2010, Ministry of Finance issued the Notification of 2010 No.104 Provision, Administration of Educational Tuition Fees Collection for Central Government Organizations. It regulates the collection of education fees in central government organizations. Centralized Treasury Payment System (CTPS) is one of the important aspects in the reform of China's finance administration system. The application of CTPS in universities and colleges will exert a widespread and profound influ- ence on budgeting, finance and accounting management. This paper discusses the requirements of the 104 Provision, analyzes the problems and possible solutions with respect to the implementation of CTPS.

  1. DESIGN APPLICATION OF HIGH STRENGTH STEEL IN GREENLAND CENTRAL PLAZA IN ZHENGZHOU%高强度钢材在郑州绿地中央广场中的应用分析

    Institute of Scientific and Technical Information of China (English)

    逄靖华; 吴宏磊; 邱林波

    2014-01-01

    为推动高强钢材在民用建筑领域的应用发展,在郑州绿地中央广场工程中对高强度钢材进行设计应用。设计过程中对高强钢的材料强度与设计参数深入研究,并对高强钢应用前后结构关键整体指标进行对比分析。研究表明,高强钢在高层建筑中的应用可使钢材节约率达20%,对结构整体指标基本无影响。应加强高强钢材在民用建筑中的设计应用。%To promote more rapid development and application of high strength steel in China , the material was applied in Greenland Central Plaza in Zhengzhou .The material strength and design parameters were studied , and the building’s structural key indexes before and after the application of the high strength steel are analyzed .The study shows that when the high strength steel is applied in a high-rise building 20% steel can be saved without any influence to the structure response .The application of high strength steel in civil buildings should be promoted .

  2. Central Asia, Physical Geography Handbook.

    Science.gov (United States)

    2007-11-02

    over 2,000 m) is not applicable to Central Asia, partly because the general hypsometric level of this region is high and unstable, as a consequence of...organic fossils in them, gastropods have been discovered. On the main territory of the Tarim massif, which evidently represented a weakly elevated...places seams of gypsum and rock salt, and, in a part to the west of the town of Aksu, also a bed of gray limestone with small fresh- water gastropods

  3. NIDDK Central Repository

    Data.gov (United States)

    U.S. Department of Health & Human Services — The NIDDK Central Repository stores biosamples, genetic and other data collected in designated NIDDK-funded clinical studies. The purpose of the NIDDK Central...

  4. Central Neuropathic Pain Syndromes.

    Science.gov (United States)

    Watson, James C; Sandroni, Paola

    2016-03-01

    Chronic pain is common in patients with neurologic complications of a central nervous system insult such as stroke. The pain is most commonly musculoskeletal or related to obligatory overuse of neurologically unaffected limbs. However, neuropathic pain can result directly from the central nervous system injury. Impaired sensory discrimination can make it challenging to differentiate central neuropathic pain from other pain types or spasticity. Central neuropathic pain may also begin months to years after the injury, further obscuring recognition of its association with a past neurologic injury. This review focuses on unique clinical features that help distinguish central neuropathic pain. The most common clinical central pain syndromes-central poststroke pain, multiple sclerosis-related pain, and spinal cord injury-related pain-are reviewed in detail. Recent progress in understanding of the pathogenesis of central neuropathic pain is reviewed, and pharmacological, surgical, and neuromodulatory treatments of this notoriously difficult to treat pain syndrome are discussed.

  5. Central venous catheter - flushing

    Science.gov (United States)

    ... during cancer treatment Bone marrow transplant - discharge Central venous catheter - dressing change Peripherally inserted central catheter - flushing Sterile technique Surgical wound care - open Review Date 9/22/2016 Updated by: ...

  6. Applications of the monitor of loose parts in the cycle 6 of the Laguna Verde Unit 2 power plant; Aplicaciones del monitor de partes sueltas en el ciclo 6 de la Unidad 2 de la central Laguna Verde

    Energy Technology Data Exchange (ETDEWEB)

    Calleros, G.; Mendez, A.; Gomez, R.A. [Comision Federal de Electricidad, Central Nucleoelectrica Laguna Verde, Veracruz (Mexico); Castillo, R.; Bravo, J.M. [ININ, A.P. 18-1027, 11801 Mexico D.F. (Mexico)]. E-mail: gcm9acpp@cfe.gob.mx

    2004-07-01

    The monitor of loose parts (Loose Parts Monitoring System) installed in the Unit 2 of the Laguna Verde Central is a tool to detect strange objects or parts loose in the system of refrigeration of the reactor that could be impacted in the walls of the recirculation knots or in the internal of the reactor. In this work two applications are shown carried out with the Monitor of Loose Parts, determining the characteristics of the stable nominal conditions, those which when changing, they are used to diagnose during the Cycle 6 of the Unit 2, failures in the components of the the recirculation circuits or to identify mechanical vibrations of the recirculation knots induced by a flow of recirculation bistable associated to operative conditions of the reactor. (Author)

  7. 消毒供应中心质量追溯管理系统设计与应用%Design and Application of Quality Tacing Management System in Central Sterile Supply Department

    Institute of Scientific and Technical Information of China (English)

    曾美凤; 曾宏; 刘承军; 郭国斌

    2011-01-01

    The process of the quality tracing management for the central sterile supply department in the l80th Hospital of PLA is introduced. The development and application of the information management system are explicated. The design functions and operation effectiveness of the system are analyzed selectively, which will provide a certain reference for the informatization management in the similar units.%介绍了解放军第180医院消毒供应中心的质量追溯管理过程,阐述其信息管理系统的开发应用情况,主要分析该系统的功能设计及其运行效果,为同类单位的信息化管理提供一定的借鉴.

  8. 集中式制播一体网架构及应用%A Perception on TV Centralized Network System of Producing and Broadcasting, and Its Application

    Institute of Scientific and Technical Information of China (English)

    陈泽华; 王海峰

    2012-01-01

    With the digitalization, high definition,integration and networking of broadcast television and the rap- new media development, through the building of digitalized and networked broadcast system to realize the pro- duction line for programming, broadcasting and storage administration, in order to further optimize work process, improve productivity and administration standard, it put forward higher request for programming and safe broad- casting and reliability of television station. To construct a centralized whole - station network including program- ming, broadcasting, recording, filing and backup, could satisfy the requirement in programming operation and solve security problem in system interconnection among whole station network, support and integrate digital broadcasting, website, outdoor media and other new media, realize net publishment of media resource, broad- cast programs webcast and some new operation, so that to widen the channel of income for station.%构建一个集节目制作、播出、收录、归档及备份于一体的集中式全台网,既满足节目制作的业务需求,又很好地解决全台网建设中关于系统互联互通的安全问题,实现对数据广播、网站、户外媒体等新媒体的支持和整合功能,实现媒资素材的网络发布、广播电视节目的网络直播等新业务开发,拓宽创收渠道。主要介绍集中式制播一体网的技术架构、系统组成、关键设备选型及安全设计与应用。

  9. Applications of seismic pattern recognition and gravity inversion techniques to obtain enhanced subsurface images of the Earth's crust under the Central Metasedimentary Belt, Grenville Province, Ontario

    Science.gov (United States)

    Roy, Baishali; Mereu, R. F.

    2000-12-01

    Project Lithoprobe's Abitibi-Grenville transect seismic reflection lines 32 and 33 traverse the exposed Central Metasedimentary Belt (CMB) located in the Grenville province of the Precambrian Shield of Canada in southern Ontario. These seismic lines image a zone with a protracted deformational history spanning more than 300Myr. Detailed examination of the commercially processed stacked sections reveals a number of significant deficiencies in some important areas. The image quality in these zones of reduced coherency needs to be enhanced to examine specific features and their relation to the surface geology. Examination of near-vertical seismic data from Lines 32 and 33 revealed that the signal-to-noise ratio was not improved by stacking, due to misalignment of signals even after static, normal moveout corrections and residual static corrections. The presumed reason is that reflected seismic energy following long ray paths in heterogeneous media suffers from relative advances and delays in its propagation, and hence arrives at slightly different times at the receivers, tending to be poorly aligned relative to its theoretical traveltime curves. A pattern recognition (PR) method for signal enhancement followed by energy stacking in moving time windows was used in this study to improve the images in spite of misalignments. Reprocessing has refined the geometry of the reflection profiles. The objective of this paper is to use enhanced images of the seismic reflection data obtained by using a PR approach together with gravity data, using 2.5-D forward and 3-D inversion routines, to give an improved model of subsurface structure in the vicinity of lines 32 and 33. Line 32 is dominated by southeast-dipping reflectors soling into the lower crust. The listric geometry of the strong reflection packages of the CMB boundary thrust zone is interpreted to represent a crustal-scale ramp-flat geometry that accommodated northwest-directed tectonic transport of the CMB. This

  10. Contribution of ground surface altitude difference to thermal anomaly detection using satellite images: Application to volcanic/geothermal complexes in the Andes of Central Chile

    Science.gov (United States)

    Gutiérrez, Francisco J.; Lemus, Martín; Parada, Miguel A.; Benavente, Oscar M.; Aguilera, Felipe A.

    2012-09-01

    Detection of thermal anomalies in volcanic-geothermal areas using remote sensing methodologies requires the subtraction of temperatures, not provided by geothermal manifestations (e.g. hot springs, fumaroles, active craters), from satellite image kinetic temperature, which is assumed to correspond to the ground surface temperature. Temperatures that have been subtracted in current models include those derived from the atmospheric transmittance, reflectance of the Earth's surface (albedo), topography effect, thermal inertia and geographic position effect. We propose a model that includes a new parameter (K) that accounts for the variation of temperature with ground surface altitude difference in areas where steep relief exists. The proposed model was developed and applied, using ASTER satellite images, in two Andean volcanic/geothermal complexes (Descabezado Grande-Cerro Azul Volcanic Complex and Planchón-Peteroa-Azufre Volcanic Complex) where field data of atmosphere and ground surface temperature as well as radiation for albedo calibration were obtained in 10 selected sites. The study area was divided into three zones (Northern, Central and Southern zones) where the thermal anomalies were obtained independently. K value calculated for night images of the three zones are better constrained and resulted to be very similar to the Environmental Lapse Rate (ELR) determined for a stable atmosphere (ELR > 7 °C/km). Using the proposed model, numerous thermal anomalies in areas of ≥ 90 m × 90 m were identified that were successfully cross-checked in the field. Night images provide more reliable information for thermal anomaly detection than day images because they record higher temperature contrast between geothermal areas and its surroundings and correspond to more stable atmospheric condition at the time of image acquisition.

  11. 高校食堂营养卫生管理措施研究%A STUDY ON THE NUTRITION AND HEALTH MANAGEMENT MEASURES IN THE UNIVERSITY CAF-ETERIA

    Institute of Scientific and Technical Information of China (English)

    张慧霞; 赵雁

    2016-01-01

    Objective To evaluate the effect of the intervention measures on the dining room of the universi-ty,and to study the problems in the management of the college cafeteria and the corresponding management measures.Methods In 2013,the school dining room inspection before intervention,as the control group, while in 2014,they were as the observation group after intervention.Using the method of field test,the problems were recorded in the range of inspection,then the questionnaire was performed on the students for dining room hygiene and safety.Results Through administrative intervention in the observation group, the tableware link bacteria total qualified rate increased by 17.23%,the qualified rate of coliform group in-creased by 16.39%.Before and after the intervention,the satisfaction of students was obviously improve-ment for the school canteen meal.Conclusions After administrative intervention,the sampling of the col-lege cafeteria,the total qualified rate of bacteria,and coli group are improved.The satisfaction of students in the questionnaire for the quality of food hygiene and safety is high.%目的:评价对高校食堂进行干预措施后的效果,在管理高校食堂中遇到问题以及相应管理措施的研究。方法对学校食堂检查2013年1—12月是干预前,作为对照组;2014年1—12月是干预后,作为观察组,采用现场试验的方法,记录检查范围内出现的问题;对在校进餐师生进行食堂卫生安全的调查问卷。结果通过行政干预后观察组的检测食具环节细菌总数合格率升高了17.23%,大肠菌群合格率升高了16.39%;食堂干预前后,在校进餐的学校对食堂的满意度明显提高。结论对食堂进行行政性干预后,高校食堂在采样环节在细菌总数合格率以及大肠菌群均有所提高,学生在调查问卷中对食堂卫生安全满意度提高,说行政干预直接对提高高校食堂卫生安全和提升师生对食堂满意度很有效果,值得推广。

  12. Evaluation on Food Safety Risks in the Railway In-house Cafeterias in Jilin Province%吉林省铁路内部食堂食品安全风险评估

    Institute of Scientific and Technical Information of China (English)

    刘锐

    2016-01-01

    Objective To analyze the food safety risks in the railway in-house cafeterias and provide guidance for better carrying out health supervision work. Methods The supervision condition of railway cafeterias in 2015 was counted and classified and summarized according to the catering service food safety supervision dynamic rating list. Results The issues of “facilities and equipment” and “purchase and storage” in the catering service food safety supervision dynamic rating list were the most, respectively accounted for 40.2% and 35.3% in the total number of issues, and the causes were no separate use of equipment, instrument and container according to classification, no difference identification, failing to meet require-ments of certificate and invoice and inspection record, no separate and classification storage of food according to the speci-fications, no regular maintenance and cleaning of equipment, inadequate self-management, limited macro-environment and incomplete supervision management legal provisions. Conclusion We should increase the responsibility awareness, imple-ment the responsibilities to individual, increase investment, guide staff to participate in the supervision and form the food safety mutual administration.%目的:分析管内铁路食堂的食品安全风险所在,为更好开展卫生监督工作提供指向。方法统计2015年铁路食堂监督情况并将问题按“餐饮服务食品安全监督动态等级评定表”分类汇总。结果在“餐饮服务食品安全监督动态等级评定表”中“设施设备”和“采购贮存”两项存在问题最多,分别占问题总数的40.2%和35.3%,主要是设备、工具和容器未按类别分开使用、无区分标识,索证索票、查验记录不符合要求,食品未按规定分开、分类贮存,设备未定期维护、保洁等。自身管理不到位、大环境所限及监督管理法律条款的不完善都是导致问题出现

  13. Application of Chromium Stable Isotopes to the Evaluation of Cr(VI) Contamination in Groundwater and Rock Leachates from Central Euboea, the Assopos Basin and Thebes Valley (Greece)

    Science.gov (United States)

    Frei, R.; Frei, K. M.; Economou-Eliopoulos, M.; Atsarou, C.; Koilakos, D.

    2014-12-01

    In order to identify the source(s) of toxic Cr(VI) prevalent in drinking and irrigation waters of Central Euboea (CE), the Assopos Basin (AB) and the Thebes Valley (TV;Greece), we have analyzed stable Cr isotopes, together with major and trace elements in porous, karstic and ultramafic mélange-hosted aquifers and groundwaters, ultramafic rocks from the hinterlands and soil samples from cultivated sites of this region. In addition we complemented our data with experimentally produced water leachates of rocks and soils. Mg/Ca ratios >1 in much of the water samples indicate the influence of ultramafic rocks which dominate the geology on the geochemical composition of the groundwaters. Elevated Cr(VI) concentrations in experimental soil leachates, compared to those in rock pulp leachates, can be potentially explained by the presence of larger amounts of Fe(II) and lower amounts of Mn(IV) in the country rocks. Factor analysis on the 17 water samples from TV indicates a strong relationship between Na, Cl-, and Cr(VI), and also points to an aversion of Cr(VI) to nitrates (fertilizer-sewage sourced) and its independency from Mg and SiO2. Assuming that redox processes produce significant Cr isotope fractionation (groundwater δ53Cr values range between +0.62 and +1.99‰), the compilation of the analytical data suggests that the dominant cause of Cr isotope fractionation is post-mobilization reduction of Cr(VI). However, the lack of a clear negative relationship between Cr(VI) concentrations and δ53Cr values may reflect that other processes complicate this interpretation. The variation in δ53Cr values, together with the results from the experimentally produced ultramafic rock pulp leachates, imply initial oxidative mobilization of Cr(VI) from the ultramafic host rocks, followed by reductive processes, as the main reason for the toxicity of the groundwaters. Using a Rayleigh distillation model and different fractionation factors of Cr(VI) reduction valid for aqueous Fe

  14. Chronic administration of grape-seed polyphenols attenuates the development of hypertension and improves other cardiometabolic risk factors associated with the metabolic syndrome in cafeteria diet-fed rats.

    Science.gov (United States)

    Pons, Zara; Margalef, Maria; Bravo, Francisca I; Arola-Arnal, Anna; Muguerza, Begoña

    2017-01-01

    The effects of grape-seed polyphenols against the development of hypertension and other cardiometabolic conditions associated with the metabolic syndrome (MetS) were studied in rats fed a high-fat, high-carbohydrate diet, known as the cafeteria (CAF) diet. Two groups of Wistar rats were fed standard (STD) or CAF diets for 12 weeks. The CAF diet-fed rats were administered different doses of a low-molecular-weight grape-seed polyphenol extract (LM-GSPE) (25, 100 and 200 mg/kg per d) or vehicle daily, and the STD diet-fed rats were administered LM-GSPE (100 mg/kg per d) or vehicle using ten animals per group. Body weight (BW), waist perimeter (WP) and systolic and diastolic blood pressures (BP) by the tail-cuff method were recorded weekly. The animals were housed in metabolic chambers every 2 weeks to estimate daily food and liquid intakes and to collect faeces and urine samples. The plasma lipid profile was analysed at time 0 and on the 4th, 7th, 10th and 12th weeks of the experiment. Moreover, plasma leptin was measured at the end of the experiment. Results demonstrated that LM-GSPE, when administered with the CAF diet, attenuated the increase in BP, BW, WP and improved lipid metabolism in these animals. However, although the 25- and 100-mg/kg per d doses were sufficient to produce beneficial effects on BP and lipid metabolism, a 200-mg/kg per d dose was necessary to have an effect on BW and WP. The present findings suggest that LM-GSPE is a good candidate for a BP-lowering agent that can also ameliorate other conditions associated with the MetS.

  15. Dynamic modelling of future land use change under urbanization and climate change pressures: application to a case study in central Belgium

    Science.gov (United States)

    Jacquemin, I.; Fontaine, C. M.; Dendoncker, N.; François, L.; De Vreese, R.; Marek, A.; Mortelmans, D.; Van Herzele, A.; Devillet, G.

    2012-04-01

    version of the model developed for natural vegetation has been upgraded to include crop systems and pastures. The ABM (Murray-Rust, Journal of Land Use Science, 6(2-3):83-99, 2011) describes the management choices (e.g., crop rotation, intensive agriculture or organic farming, etc) for each land plot, as well as the possible change in their affectation (e.g., conversion of farm fields to residential areas in response to urbanization), under different socio-economic contexts described in the storyline of three scenarios depicting general societal orientations (business-as-usual; market oriented; sustainability oriented). As a result, the ABM produces a dynamic evolution of land use and management options to be passed on to the DVM for further analysis. The outputs from the DVM allow evaluating quantitatively the provision of EGS by each land plot. This DVM-ABM modelling tool is thus able to describe the future evolution of land use and land cover, as well as of EGS production, in the context of socio-economic scenarios. The model is applied to a case study area covering four municipalities located in central Belgium close to Brussels and Leuven. The area is mostly composed of agricultural fields (crops and meadows), residential areas and a large protected forest (Meerdaalbos) and is subject to intense urbanization pressure due to the proximity to Brussels.

  16. Applications of Plackett–Burman and Central Composite Design for the Optimization of Novel Brevundimonas diminuta KT277492 Chitinase Production, Investigation of its Antifungal Activity

    Directory of Open Access Journals (Sweden)

    E. Ashour Warda

    Full Text Available ABSTRACT Biological control strategy which can damage chitin, a vital component of pathogenic fungi and arthropods promises a safe solution for many fungal problems. And it’s more favorable than chemicals which increase health risks and environmental problems. Thus, the chitinase producers appear potential candidates of biological control of pathogenic fungi. Brevundimonus diminuta KT277492 is a new isolate that has been isolated recently from Egyptian soil. Significant factors that affecting the chitinase enzyme production were studied and optimized using Plackett-Burman and Response Surface Methodology (RSM. As a result, maximum production of chitinase enzyme was 832.87 IUL-1, this result presented about 8.767-fold increase in the enzyme production. In the last phase of the study, partially purified chitinase enzyme obtained from B. diminuta KT277492 was tested against two pathogenic fungi and the results showed good inhibitory activity against A. alternata and F. solani with IZD of 31±0.25 and 25±0.91 mm respectively. Finally, obtained results indicated the value of optimization process and the optimized chitinase enzyme could be an excellent choice in application of food and biotechnology as a biofungicide. This reflects the necessity of studying the characteristics and kinetics of the enzyme in the forthcoming study.

  17. A Central European precipitation climatology – Part II: Application of the high-resolution HYRAS data for COSMO-CLM evaluation

    Directory of Open Access Journals (Sweden)

    Susanne Brienen

    2016-05-01

    of small values. The maximum values of the different indices across the whole HYRAS-PRE domain are underestimated by 3–20 %. The regional variability is not very high but with a slight orographic dependence. Problems with areas of low station density can also be detected. In conclusion, this study shows that good-quality observational data sets at high-resolution are essential for a correct evaluation of the performance of RCMs designed for applications at high spatial resolution.

  18. A handbook for solar central receiver design

    Energy Technology Data Exchange (ETDEWEB)

    Falcone, P.K.

    1986-12-01

    This Handbook describes central receiver technology for solar thermal power plants. It contains a description and assessment of the major components in a central receiver system configured for utility scale production of electricity using Rankine-cycle steam turbines. It also describes procedures to size and optimize a plant and discussed examples from recent system analyses. Information concerning site selection criteria, cost estimation, construction, and operation and maintenance is also included, which should enable readers to perform design analyses for specific applications.

  19. 厂拌热再生沥青混合料在含LSPM路面结构中的应用及评价%Application and Evaluation of Asphalt Mixture by Central Plant Hot Recycling in Pavement Structure with LSPM

    Institute of Scientific and Technical Information of China (English)

    薛彦卿; 黄晓明

    2011-01-01

    Firstly, the reclaimed asphalt pavement was detected, and further mixing proportion of as-phalt mixture AC-20/AC-25 by central plant hot recycling was designed. Secondly, the compressive strength and the compressive resilience modulus of the mixture with different RAP percentages were tested with pressure machine and MTS-810 respectively at 15 and 20℃. Next, the change laws were analyzed and the value ranges were recommended. Finally, structural analysis and evaluation were carried out for over-laid asphalt pavement and perpetual pavement by central plant hot recycling with LSPM so as to demon-strate the technical feasibility of the mixture used as structural layer of surface course in pavement struc-ture with LSPM. The studies have suggested that, for overlaid asphalt pavement by central plant hot recy-cling with LSPM, the compressive resilience modulus of the recycled mixture needs testing in design and the tensile stress at the bottom of recycled structural layer needs checking according to specifications. Mo-reover , the application of recycled mixture in perpetual pavement with LSPM can satisfy the design control indexes.%首先对回收沥青路面材料(RAP)进行了检测,进而设计了厂拌热再生沥青混合料AC-20与AC-25的配合比.其次,利用压力机和MTS-810测定了其不同RAP掺配比例下15℃和20℃抗压强度和抗压回弹模量,分析了变化规律并推荐取值范围.最后,针对含LSPM厂拌热再生加铺沥青路面与含LSPM厂拌热再生永久性路面,进行了结构分析与评价,论证了厂拌热再生沥青混合料作为面层结构层应用于含LSPM路面结构在技术上的可行性.研究表明,对于含LSPM厂拌热再生加铺沥青路面,设计时有必要实测厂拌热再生沥青混合料的抗压回弹模量,并验算该结构层底弯拉应力是否满足规范要求;将厂拌热再生沥青混合料应用于含LSPM的永久性路面能满足设计控制指标.

  20. Application of Electrocardiogram in Central Venous Catheterization for Patients with Tumors%心电导联中心静脉置管技术在肿瘤患者中的应用体会

    Institute of Scientific and Technical Information of China (English)

    吴耀红; 俞新燕

    2013-01-01

    This paper introduced the application of electrocardiogram in central venous catheterization for 326 patients with tumors and its nursing care. With the change of P wave of electrocardiography, the central venous catheter tip could be inspected, which contributed to the improvement of success rate and there was less radioactive pollution from X-ray and less local hemorrhage in puncture point. All catheters were successfully placed and the success rate was improved. Since no change of P wave was detected, the central venous catheter was placed with X-ray positioning among six patients. Oozing lasted in puncture point among 78 patients for 2 to 3 days and stopped after treatment. The communication between patients and nurses played a critical part in the whole process. Successful completion of chemotherapy was witnessed in all patients in the study.%  总结326例肿瘤患者在中心静脉置管过程中应用心电导联技术的护理经验。通过穿刺过程中加强护患沟通,利用心电图P波改变及时调整导管尖端位置,改变穿刺方法,提高了穿刺成功率,减少了X线的放射性污染及穿刺点的局部出血。本组326例患者均成功置管,1次置管成功率相比传统中心静脉置管提高了约4%。本组6例患者在未见P波改变情况下,改用 X线定位;78例患者穿刺处少量渗血持续2~3 d,经积极处理后,出血停止。所有病例均顺利完成化疗。

  1. Central Laboratories Services

    Data.gov (United States)

    Federal Laboratory Consortium — The TVA Central Laboratories Services is a comprehensive technical support center, offering you a complete range of scientific, engineering, and technical services....

  2. 检查表法在农村集中式供水系统风险评价的应用%Application of Checklist Method in Risk Assessment of Rural Centralized Water Supply System in China

    Institute of Scientific and Technical Information of China (English)

    李洪兴; 陶勇; 张荣

    2012-01-01

    目的 探讨检查表法在农村集中式供水系统进行风险评价的应用.方法 选择某省以地面水和地下水为水源的水厂各一家,依据相关的标准规范建立检查表并对两水厂进行现场检查,应用半定量评价模型对风险等级进行评价;综合考虑定性和定量评价的结果,判定“风险易发点”.结果 风险检查结果和半定量评价结果显示,两家水厂水源地均存在一定水质风险;水源的综合评价信息显示,一家水厂的水源风险等级为中度且为“风险易发点”.结论 检查法可以发现了两水厂的潜在风险并进行风险度评价;该方法简单易用,具有一定推广价值.%Objective To assess the risk of rural centralized water supply systems by using the checklist method and semi-quantitative method.Methods A water plant using surface water source and a water plant using underground water source in the same province were selected as the study objects.The sanitary inspection on these two water supply facilities was carried out by the application of Checklist developed according to the current related standards,regulations and semi-quantitative method,and the high risk points were identified based on assessment results.Results There were risk factors in the two water supply facilities,but one of the water plants had high risk in water source,with which had the high risk point.Conclusion The potential risks have been found in water source by the application of the checklist method and semi-quantitative method.The checklist method and semi-quantitative methods are simple for the risk assessment and management of rural centralized water supply system in China.

  3. Novel central nervous system drug delivery systems.

    Science.gov (United States)

    Stockwell, Jocelyn; Abdi, Nabiha; Lu, Xiaofan; Maheshwari, Oshin; Taghibiglou, Changiz

    2014-05-01

    For decades, biomedical and pharmaceutical researchers have worked to devise new and more effective therapeutics to treat diseases affecting the central nervous system. The blood-brain barrier effectively protects the brain, but poses a profound challenge to drug delivery across this barrier. Many traditional drugs cannot cross the blood-brain barrier in appreciable concentrations, with less than 1% of most drugs reaching the central nervous system, leading to a lack of available treatments for many central nervous system diseases, such as stroke, neurodegenerative disorders, and brain tumors. Due to the ineffective nature of most treatments for central nervous system disorders, the development of novel drug delivery systems is an area of great interest and active research. Multiple novel strategies show promise for effective central nervous system drug delivery, giving potential for more effective and safer therapies in the future. This review outlines several novel drug delivery techniques, including intranasal drug delivery, nanoparticles, drug modifications, convection-enhanced infusion, and ultrasound-mediated drug delivery. It also assesses possible clinical applications, limitations, and examples of current clinical and preclinical research for each of these drug delivery approaches. Improved central nervous system drug delivery is extremely important and will allow for improved treatment of central nervous system diseases, causing improved therapies for those who are affected by central nervous system diseases.

  4. Central Pain Syndrome

    Science.gov (United States)

    ... or hands. Central pain syndrome often begins shortly after the causative injury or damage, but may be delayed by months or even years, especially if it is related to post-stroke pain. × Definition Central pain syndrome is a neurological ...

  5. Central centrifugal cicatricial alopecia

    Directory of Open Access Journals (Sweden)

    Collin Blattner

    2013-01-01

    Full Text Available Central centrifugal cicatricial alopecia is a common cause of progressive permanent apical alopecia. This unique form of alopecia includes entities previously know as "hot comb alopecia," "follicular degeneration syndrome," "pseudopelade" in African Americans and "central elliptical pseudopelade" in Caucasians. The etiology appears to be multifactorial and the condition occurs in all races.

  6. Optimal central bank transparency

    NARCIS (Netherlands)

    van der Cruijsen, C.A.B.; Eijffinger, S.C.W.; Hoogduin, L.

    2008-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  7. Optimal central bank transparency

    NARCIS (Netherlands)

    van der Cruijsen, C.A.B.; Eijffinger, S.C.W.; Hoogduin, L.H.

    2010-01-01

    Should central banks increase their degree of transparency any further? We show that there is likely to be an optimal intermediate degree of central bank transparency. Up to this optimum more transparency is desirable: it improves the quality of private sector inflation forecasts. But beyond the opt

  8. 2007-2011年宁德城区学校食堂餐具检测%Testing Results of School Cafeteria Tableware in Ningde City, 2007-2011

    Institute of Scientific and Technical Information of China (English)

    张朝晖

    2012-01-01

    Objective To understand the sterilization quality of tableware in school cafeteria, in order to ensure the health of students and provide basis for safety management of group meal. Methods Random samples of school tableware which were provided for students to use were selected. As for testing method, rapid - testing papers were used to detect coliform group, according to the Ministry of Health's " Hygiene standard for disinfection of dinner and drinking set ". Results From 2007 to 2011, altogether 1421 tableware sets were spot - chek-ced. The total passing rate was 78. 40% , which showed that annual passing rate is rising. No significant difference was identified among different types of tableware sets. Conclusion Strengthening education of tableware disinfection supervision, increasing consciousness and cultivation of disinfection norms of operation habits are the major factors to improve the health quality of the of tableware.%目的 了解学校食堂餐具消毒状况,为确保学生身体健康和集体用餐安全管理提供依据.方法 随机抽取学校提供学生使用的餐具,采用快速检测纸片检测大肠菌群,按照卫生部“餐(饮)具消毒卫生标准”规定的方法进行检测.结果 2007-2011年共抽检餐饮具1 421件,总合格率为78.40%,各年度合格率呈逐年上升趋势.不同学段餐具消毒合格率无显著性差异.不同餐具合格率无显著性差异.结论 加强学校餐具消毒监管力度,增强消毒意识和培养规范操作习惯是提高餐具消毒卫生质量的主要因素.

  9. The Development and Application of CSG Technology Intelligence Central System%南方电网技术情报中心系统的研发与应用

    Institute of Scientific and Technical Information of China (English)

    龚婷; 周育忠; 韦嵘晖; 王庆红

    2012-01-01

    The primary goal of creating an electric power intelligence system is to set up a scientific and reasonable intelligence work system.This paper introduces the development and application of CSG technology intelligence central system,including its design concept as well as the design and accomplishment of its four function modules.The characteristics of the system are reflected by the humanization intelligence services in its functions of information searching,processing and publishing as well as intelligence topics,intelligence album,original text delivery and SDI(selective dissemination of information) service.%电力情报系统建设的首要目标是建立一套科学的、合理的技术情报工作体系。阐述了南方电网技术情报中心系统的开发及应用,包括系统设计理念及其四大功能模块的设计与实现。该系统的特点体现在信息检索、加工处理和发布、情报专题、情报专辑、原文传递、定题服务等人性化情报服务项目上。

  10. 运用改良塞丁格技术行PICC穿刺的临床应用%Clinical application of modified Seldinger technique in peripherally inserted central catheters (PICC)

    Institute of Scientific and Technical Information of China (English)

    付小伟; 孙洪涛

    2012-01-01

    Objective To explore the clinical application of modified Seldinger technique in peripherally inserted central catheters ( PICC ). Methods Ten patients were included in the study with poor visible blood vessel. The modified Sledinger technique was employed to perform PICC. Results All of the 10 patients have been successfully catheterized by the modified Seldinger technique with a success rate of 100%. No complications occurred within seven days after catheterization. Conclusion The modified Seldinger technique overcomes the limitation of the routine PICC on the visibility of blood vessel.It greatly improves the success rale of catheterization and reduces the incidence of complications.%目的 探讨运用改良塞J格技术行PICC穿刺置管的临床应用.方法 10例患者,外观及触摸血管状况极差,使用改良塞丁格技术,行PICC穿刺.结果 10例患者一次性穿刺成功率为100%,术后7d内观察没有并发症发生.结论 此技术解决了传统置管方法受血管条件限制的局限性,大大提高了 PICC置管成功率,减少了并发症.

  11. The central peak revisited

    Energy Technology Data Exchange (ETDEWEB)

    Shirane, G.

    1995-10-27

    The central peak in SrTiO{sub 3} was first observed by Riste and his collaborators in 1971. This was one of the key discoveries leading to an understanding of the dynamics of phase transitions. The most recent discovery of two length scales in SrTiO{sub 3} motivated a reinvestigation of the soft phonon and associated central peak by neutron scattering. These recent experiments shed new light on the nature of the central peak. It is now well established to be strongly sample dependent and it originates from defects in bulk crystals.

  12. Imaging central pain syndromes.

    Science.gov (United States)

    Veldhuijzen, Dieuwke S; Greenspan, Joel D; Kim, Jong H; Coghill, Robert C; Treede, Rolf-Detlef; Ohara, Shinji; Lenz, Frederick A

    2007-06-01

    Anatomic, functional, and neurochemical imaging studies have provided new investigative tools in the study of central pain. High-resolution imaging studies allow for precise determination of lesion location, whereas functional neuroimaging studies measure pathophysiologic consequences of injury to the central nervous system. Additionally, magnetic resonance spectroscopy evaluates lesion-induced neurochemical changes in specific brain regions that may be related to central pain. The small number of studies to date precludes definitive conclusions, but the recent findings provide information that either supports or refutes current hypotheses and can serve to generate new ideas.

  13. 授权式教育在行PICC化疗患儿家属健康教育中的应用%Application of empowerment education in health education of families of children receiving chemotherapy with percutaneously inserted central catheter

    Institute of Scientific and Technical Information of China (English)

    沈燕; 周玉峰; 王娟

    2014-01-01

    Objective To study the application effects of empowerment education in health education for families of children receiving chemotherapy with percutaneously inserted central catheter .Method Thirty five families of chil-dren diagnosed with malignancy and placed with percutaneously inserted central catheter (PICC) were enrolled in this study .Anxiety indexes of families of children before and after placed with PICC were assessed by Self-rating anxiety scale (SAS) established by Zung .Knowledge level of before and after PICC placement was evaluated by homemade health education evaluation .Result Compared with the parents of children before PICC treatment ,they known better of PICC after empowerment education (P< 0 .05) .Parents'anxiety was significantly reduced after PICC treatment ,There was significant differences between the two (P<0 .05) .Conclusion Empowerment education makes the families to participate in all aspects of health care ,changing their behavior and mental fitness and impro-ving their autonomy participation significantly .%目的:探讨授权式教育在行PICC化疗患儿家属健康教育中应用的效果。方法选取确诊为恶性肿瘤患儿行PICC置管的家属35例,分别在置管前和置管后采用Zung焦虑自评量表(SAS)测定家属焦虑指数,应用自制健康教育评价表观察比较置管前后家属对置管相关知识的掌握情况。结果置管后患儿家属对授权式教育获得的PICC知识掌握情况优于置管前(P<0.05),焦虑情绪明显减轻,与置管前相比差异有显著意义(P<0.05)。结论授权式教育让家庭参与健康照顾的各个方面,改变患儿家属行为方式和心理适应度,明显提升了患儿家属的自主性和参与性。

  14. Central nervous system resuscitation

    DEFF Research Database (Denmark)

    McIntosh, T K; Garde, E; Saatman, K E;

    1997-01-01

    Traumatic injury to the central nervous system induces delayed neuronal death, which may be mediated by acute and chronic neurochemical changes. Experimental identification of these injury mechanisms and elucidation of the neurochemical cascade following trauma may provide enhanced opportunities ...

  15. Central Asian Republic Info

    Data.gov (United States)

    US Agency for International Development — CAR Info is designed and managed by the Central Asian Republic Mission to fill in the knowledge and reporting gaps in existing agency systems for that Mission. It...

  16. Central nervous system

    Science.gov (United States)

    The central nervous system is composed of the brain and spinal cord. Your brain and spinal cord serve as the main "processing center" for your entire nervous system. They control all the workings of your body.

  17. Central nervous system resuscitation

    DEFF Research Database (Denmark)

    McIntosh, T K; Garde, E; Saatman, K E

    1997-01-01

    Traumatic injury to the central nervous system induces delayed neuronal death, which may be mediated by acute and chronic neurochemical changes. Experimental identification of these injury mechanisms and elucidation of the neurochemical cascade following trauma may provide enhanced opportunities...

  18. "Central Station" Londonis

    Index Scriptorium Estoniae

    2000-01-01

    Londoni galeriis Milch seitsme läti, leedu ja eesti kunstniku projekt "Central Station". Kuraatorid Lisa Panting, Sally Tallant. Eestist osalevad Hanno Soans (Catarina Campinoga koostöös valminud video), Kiwa, Kai Kaljo

  19. Central Station Design Options

    DEFF Research Database (Denmark)

    2011-01-01

    The purpose of EDISON Work Package 4.1 is the evaluation of possible Central (charging) Stations design options for making possible the public charging of Electric Vehicles (EVs). A number of scenarios for EVs are assessed, with special emphasis on the options of Fast Charging and Battery Swapping....... The work identifies the architecture, sizing and siting of prospective Central Stations in Denmark, which can be located at shopping centers, large car parking lots or gas stations. Central Stations are planned to be integrated in the Danish distribution grid. The Danish island of Bornholm, where a high.......g. due to vandalism, the charge supply circuit is disconnected. More electrical vehicles on the market are capable today of quick charging up to 50 kW power level. The feasibility of Central Stations with fast charging/swapping option, their capacity, design, costs and grid impact, as well as battery...

  20. Gangs in Central America

    Science.gov (United States)

    2008-10-17

    Citizen Security held in July 2008 indicated that Guatemala now has the second highest murder rate in Central America (roughly 45 per 100,000 people...training regional security forces.48 In recent years, the U.S. Southern Command has taken a leading role in discussing the problem of citizen security in...the results CRS-19 51 “Memo: The Merida Initiative and Citizen Security in Mexico and Central America,” Washington Office on Latin America, March 2008

  1. Outsourcing central banking

    DEFF Research Database (Denmark)

    Khoury, Sarkis Joseph; Wihlborg, Clas

    2005-01-01

    The literature on Currency Boards (CB) stops at the water edge in terms of dealing with the totality of the functions of a central bank. Monetary policy, and banking supervisioncan be "outsourced" in an open economy with substantial foreign direct investment (FDI)in the banking sector if political...... the feasibility of, and constraints on, outsourcing of central bank functions. A brief discussion of the Argentinian experience is used for contrast.Key words: Currency Board, Foreign Banks, Supervision, Regional Integration,outsourcing....

  2. 分时段中心静脉置管在极低出生体质量儿中的应用%Application of Combined Central Venous Catheterization in Divided Period in Very Low Birth Weight Infants

    Institute of Scientific and Technical Information of China (English)

    黄朝梅; 邵巧仪; 罗英; 邓桂珍

    2013-01-01

    Objective To explore the application of umbilical venous catheter (UVC) combined with peripherally inserted central catheter (PICC) in divided period in very low birth weight infants (VLBWI). Methods One hundred and eleven VLBWIs from January 2010 to December 2011 were divided into combined catheter group (UVC and PICC) with 51 cases and PIV (peripheral vein) plus PICC group with 60 cases. Venous catheter situation, physical indications and catheter infection during hospitalization were monitored. Results The one-shot success rate in combined catheter group was higher than that of PIV plus PICC group, but lower incidence of infusion extravasation in combined catheter group. Correction time of hypoglycemia had no significant difference between the two groups, however but the frequency of apnoea and the time of weight up to 2 kg had (P<0.01). Conclusion With combined central venous catheterization, a higher success rate of intravenous puncture could be achieved with longer retention time, but lower incidence of infusion extravasation, which provides a safe and effective venous channel for VLBWI.%  目的探讨分时段脐静脉置管和经外周静脉置入中心静脉导管(peripherally inserted central catheter,PICC)置管在极低出生体质量儿中的应用效果。方法选取2010年1月—2011年12月入院的极低出生体质量儿111例,分为分时段应用脐静脉置管、PICC组(观察组)51例和外周静脉置管加PICC组(对照组)60例,监测两组住院期间的静脉置管情况、患儿身体指征反应及导管感染情况。结果观察组PICC 1次置管成功率高于对照组,输液外渗发生率低(P<0.01);两组患儿纠正低血糖所需时间差异无统计学意义;呼吸暂停次数、体质量增长至2 kg时间经比较差异有统计学意义(P<0.01)。结论采用分时段中心静脉置管具有穿刺成功率高,留置时间长,输液外渗发生率低,且不增加感染的优点,能最大限

  3. 小剂量右美托咪定滴鼻用于中心静脉穿刺术的效果评价%Application of small dose of dexmedetomidine nasal drops in bedside central venous puncture

    Institute of Scientific and Technical Information of China (English)

    邓默; 李璐

    2015-01-01

    Objective To investigate the effect of small dose of dexmedetomidine nasal drops central venous puncture in clinical efifcacy and safety. Method 60 cases of bedside in patients with central venous puncture were randomly divided into observation group and control group, 30 cases in each group. Observation group patients before operation by nasal instillation of 0.5μg/kg dexmedetomidine, bilateral average drops, control group were treated by nasal instillation of placebo saline nose drops, operations were performed in 15 minutes prior to the start of operation. Recorded and compared between the two groups of patients with Ramsay sedation scores, visual analogue scale (VAS) after the operation of mini mental state examination scores, McGill scores, the occurrence of adverse reactions and preoperative, postoperative (MMSE) scores. Result Ramsay sedation scores in observation group significantly higher than control group, VAS, McGill scores were significantly lower than control group, the difference was signiifcant (P0.05). The two groups of patients before and after operation, MMSE scores between groups, within group comparisons showed no signiifcant difference (P>0.05). Conclusion Small dose dexmedetomidine intranasal for bedside central venous puncture, can play a mild sedative and analgesic action, brought to the puncture operation discomfort of patient satisfaction is good, without the occurrence of adverse reactions of respiratory inhibition, safe and reliable, worthy of popularization and application.%目的:探讨小剂量右美托咪定滴鼻用于中心静脉穿刺术的临床效果及安全性。方法将60例床旁中心静脉穿刺术患者随机分为观察组和对照组,每组各30例。观察组患者操作前经鼻滴入0.5μg/kg右美托咪定,双侧平均滴入,对照组患者经鼻滴入安慰剂-生理盐水,滴鼻操作均在操作前15分钟进行。记录并比较两组患者术中Ramsay镇静评分,术后视觉模拟评分法

  4. 126例中心静脉导管在血液净化中的临床应用%Application of central venous catheter in hemodialysis in 126 cases

    Institute of Scientific and Technical Information of China (English)

    肖琼; 李靖; 杨元媛; 韩志武

    2011-01-01

    Objective To discuss the complications and treatment of applying central venous catheter in hemodialysis by observing its application condition. Methods The clinical data of 126 patients with central venous catheter applied in hemodialysis were enrolled and analyzed retrospectively including 25 cases of long-term dual-lumen catheters and 101 cases of temporary dual-lumen catheters. The related complications and treatments were analyzed. Results The common complications occurred during catheterizations included inadvertent arterial puncture in 11 cases (8.73 % ) and ecchymoma in 6 cases (4.76%) while the complications of catheterizations included inadequate blood flow in 24 cases (19.04%) ,catheter related infection in 23 cases(18.25% ) ,local bleeding in 15 cases( 11.90% ) and catheter inadvertent withdrawal in 3 cases (2.38 % ). Above complications were recovered without recurrences after taking corresponding treatments. Conclusion Attention should be paid to the central venous catheter related complications. Improving technology, strengthening nursing care and taking timely treatment are the key points to prevent catheter functional failure.%目的 通过观察中心静脉留置导管在血液透析中使用状况,探讨中心静脉导管相关并发症及处理方法,改善血液透析患者预后.方法 回顾性分析126例使用中心静脉置管维持性血液透析患者的临床资料.其中25例为长期双腔导管,101例为临时双腔导管,分析中心静脉导管的相关并发症与处理效果.结果 置管过程中的常见并发症有:误穿动脉11例(8.73%)、皮下血肿6例(4.76%).导管留置并发症有:血流量不足24例(19.04%),导管相关感染23例(18.25%),穿刺部位渗血15例(11.90%),导管意外脱落3例(2.38%).以上并发症均在给予相应的处理后痊愈,未留下相关后遗症.结论 中心静脉导管相关并发症值得临床重视,提高置管技术,加强导管护理,及时处理是防范导管失功能的关键.

  5. Workers' Central Life Interests and Job Performance.

    Science.gov (United States)

    Dubin, Robert; Champoux, Joseph E.

    Supervisors' ratings of individual industrial workers appear to be related to the central life interests (CLI) of the workers. The group of workers who had a job-oriented CLI received the highest ratings from their superivsors among the three CLI groups on Initiative and Application, Cooperation and Quantity of Work and were rated low on…

  6. PDCA循环在消毒供应中心质量持续改进中的应用%Application of PDCA cycle in continuous quality improvement of central sterile supply department

    Institute of Scientific and Technical Information of China (English)

    陈洁; 李淑君; 李燕妮; 秦建; 翟智超; 董海蛟; 王聪

    2013-01-01

    OBJECTIVE To explore the application of PDCA cycle management mode in continuous quality improvement of the central sterile supply department and further strengthen the central sterile supply quality management so as to ensure zero defect of the sterile supplies.METHODS The quality control management team was established,the PDCA cycle management responsibility system was implemented,the PDCA cycle management approach was employed to set up the key points of the quality control,the PDCA cycle improvement program was developed to constantly improve the systems; the PDCA group was implemented the PDCA cycle management mode in Nov 2011,while the control group was not implemented the PDCA cycle management mode from Nov 2010 to Oct 2011,there were 96 pieces of data in each group,then the satisfaction rate was compared between the two groups.RESULTS After the implementation of the PDCA cycle management mode,the satisfaction rate of the clinical departments was 97.9% in the PDCA group,significantly higher than 91.7% of the control group,the difference was significant(P<0.05); the qualified rates of the hand hinge,monitoring of disinfectant concentration,cleaning and disinfection of surgical equipments,cleaning and disinfection of pipelines,rust removal,sterile supplies of the PDCA group were respectively 99.0%,95.5%,98.0%,97.5%,97.0%,and 100.0%,significantly higher than those of the control group (P<0.05).CONCLUSION Through the application of PDCA cycle management model and the implementation of comprehensively continuous quality improvement,the overall quality of the CSSD staff,service quality,and quality of the sterile supplies have been substantially improved.%目的 探索PDCA循环管理模式在消毒供应中心(CSSD)质量持续改进中的应用,进一步加强CSSD质量管理,保证无菌物品供应零缺陷.方法 成立质量控制管理小组,实行PDCA循环管理责任制,运用PDCA循环管理方法设定质控重

  7. Application of lean management in operation processing of central sterile supply department%精益管理在消毒供应中心操作流程中的应用

    Institute of Scientific and Technical Information of China (English)

    张炼英

    2011-01-01

    目的 探讨精益管理在消毒供应中心操作流程中的应用,以促进消毒供应中心的效率与品质改善。方法 通过国内外精益思想、精益医疗管理文献与资料的收集与整理,归纳介绍目前国内外精益管理在医疗领域的应用,对消毒供应中心实施精益管理进行探讨。结果 通过制定价值流图,流动作业,消除浪费,取得最高管理者的全力支持,从组织结构上、人员设置上、技能操作上进行变革,充分保证精益管理成功的实施。结论 通过在消毒供应中心建立价值流图分析,并利用信息技术可改善消毒供应中心消毒供应作业的流动性,重建消毒供应管理系统的业务模型,改进消毒供应的效率和质量。%Objective To study the application of lean management in operation processing of central sterile supply department(CSSD)in order to promote its efficiency and quality improvement. Methods From collecting international and domestic related literatures of lean thoughts, lean medical management, summarizing and introducing the application of lean management in medical domain, discussing the implementation of lean management in CSSD. Results The implementation of lean management was ensured to be successful through establishing value stream mapping, mobile operation, waste elimination, obtaining support of top management, reforming of organization construction, placing personal and technological operation. Conclusions The flow of operation can be improved, the business model will be re-build and the efficiency and quality of CSSD can be improved by establishing the value stream mapping in CSSD and using the information technology.

  8. The application of the ISO 14001 environmental management system to small hydropower plants; L'application de l'ISO 14001 systeme environnemental de gestion aux petites centrales hydro-electriques

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2010-07-01

    The ISO 14000 environmental management standards exist to help organisations minimise how their operations negatively affect the environment and to comply with applicable laws and regulations. More specifically, ISO 14001 is the international specification for an environmental management system (EMS). It specifies requirements for establishing an environmental policy, determining environmental aspects and impacts of products/activities/services, planning environmental objectives and measurable targets, implementation and operation of programs to meet objectives and targets, checking and corrective action, and management review. The overall idea is to establish an organized approach to systematically reduce the impact of the environmental aspects that an organization can control. Tools are available for the analysis of environmental aspects and for the generation of options for improvement. As with ISO 9000 (quality management), certification is performed by third-party organizations. Hydroelectricity enables to generate clean energy with no direct emissions of greenhouse gases and without consuming fossil fuels. However, this activity is implemented within a sensitive natural environment: the watercourses are shared with several users such as the fishermen, the kayakers, farmers and industry. Generating hydroelectricity induces very little discharges into the environment. Conversely, its implementation on the watercourses can alter the flow rates and the ecosystem: leading to disruption in the free passage of fish, change in the hydrodynamics of a watercourse, emission of noise, production of waste, pollution through oil leak, damage inflicted on the landscape, etc. These environmental impacts form the subject of several monitoring and control operations that are designed to limit and preserve the natural environment. Additionally, relations with the water users and the administrations are sometimes difficult and this would require a dialogue to be established to

  9. CENTRAL PLATEAU REMEDIATION

    Energy Technology Data Exchange (ETDEWEB)

    ROMINE, L.D.

    2006-02-01

    A systematic approach to closure planning is being implemented at the Hanford Site's Central Plateau to help achieve the goal of closure by the year 2035. The overall objective of Central Plateau remediation is to protect human health and the environment from the significant quantity of contaminated material that resulted from decades of plutonium production in support of the nation's defense. This goal will be achieved either by removing contaminants or placing the residual contaminated materials in a secure configuration that minimizes further migration to the groundwater and reduces the potential for inadvertent intrusion into contaminated sites. The approach to Central Plateau cleanup used three key concepts--closure zones, closure elements, and closure process steps--to create an organized picture of actions required to complete remediation. These actions were merged with logic ties, constraints, and required resources to produce an integrated time-phased schedule and cost profile for Central Plateau closure. Programmatic risks associated with implementation of Central Plateau closure were identified and analyzed. Actions to mitigate the most significant risks are underway while high priority remediation projects continue to make progress.

  10. The Naive Central Banker

    Directory of Open Access Journals (Sweden)

    Marcelo de Carvalho Griebeler

    2015-09-01

    Full Text Available There has been in some countries a trend of assigning other functions to central banks besides price stability. The most suggested function to be added to monetary authority’s obligations is to pursue economic growth or full employment. In this paper we characterize the behavior and analyse the optimal monetary policy of, what we call, a naive central banker. We describe the naive behavior as one that does face the inflation-unemployment trade-off, but it tries to minimize both variables simultaneously. Our findings, both under discretion and commitment, indicate that the naive central banker delivers lower expected inflation and inflation variance than the benchmark behavior whenever the economy is rigid enough. However, the degree of conservativeness also affects this result, such that the less conservative the naive policymaker, the more rigidity is necessary.

  11. SOCRATES Invades Central Europe

    Directory of Open Access Journals (Sweden)

    Joseph Slowinski

    1998-04-01

    Full Text Available The objective of this article is to explore the current reality faced by higher education students in Central and Eastern Europe and to draw out the implications of this current reality for policy makers in the future. In the article, I explore the influence of transnational corporations' training programs on education as it currently pertains to Central and Eastern European higher education and employment. In addition, multinational corporate entities exercise influence on European Union policy through the role of lobby organizations and activities. I explore the influence of these practices on education with an emphasis on the emerging importance of Western language skills. In addition, I focus on the European Union and its efforts to expand into Central and Eastern Europe in order to provide a focal point for analysis.

  12. Quantificação e análise do custo da sobra limpa em unidades de alimentação e nutrição de uma empresa de grande porte Quantification and analysis of the cost of food wastage in the cafeterias of a large company

    Directory of Open Access Journals (Sweden)

    Isabel Cristina Cordeiro Soares

    2011-08-01

    Full Text Available OBJETIVO:O propósito deste estudo foi quantificar e avaliar o custo da sobra limpa em oito unidades de alimentação e nutrição de uma empresa siderúrgica de grande porte. MÉTODOS: Foram avaliadas oito unidades de alimentação e nutrição durante cinco meses. A quantificação da sobra limpa considerou as sobras e o número de refeições planejadas e servidas diariamente. As preparações foram divididas em grupos, sendo os custos obtidos a partir do valor médio dos alimentos adquiridos no mês. RESULTADOS: Cinquenta por cento das unidades de alimentação e nutrição não atingiram valores inferiores ou iguais a 30g, meta per capita de sobra limpa determinada pela empresa. Os per capitas totais de sobra limpa variaram entre 24g e 60g, equivalentes a 176kg-1.213kg de alimentos desperdiçados mensalmente. As saladas apresentaram as maiores porcentagens de desperdício na maioria das unidades. O custo mensal com as sobras atingiu de 2,2% a 3% do valor gasto mensalmente com alimentos, representando um custo elevado para a empresa (entre 80 a 108 salários-mínimos. Diante dos resultados obtidos, foram propostas medidas de intervenção, tais como planejamento e elaboração adequada das preparações, caracterização dos clientes e ações para educação nutricional. CONCLUSÃO: As unidades de alimentação e nutrição apresentaram considerável perda de alimentos com a sobra limpa. A implementação das intervenções propostas poderá minimizar essa perda. O valor gasto com esse desperdício poderia ser revertido em melhorias nos processos produtivos.OBJECTIVE: The purpose of this study was to quantify and assess the cost of food wastage in eight cafeterias of a big steel mill. METHODS: Eight cafeterias were followed during five months. Quantification of food wastage was done considering the leftovers and the number of meals planned and served daily. For determining the cost, preparations were divided into groups, and the cost was

  13. Central arterial pressure assessment with intensity POF sensor

    Science.gov (United States)

    Leitão, Cátia; Gonçalves, Steve; Antunes, Paulo; Bastos, José M.; Pinto, João. L.; André, Paulo

    2015-09-01

    The central pressure monitoring is considered a new key factor in hypertension assessment and cardiovascular prevention. In this work, it is presented the central arterial systolic pressure assessment with an intensity based POF sensor. The device was tested in four subjects, and stable pulse waves were obtained, allowing the calculation of the central pressure for all the subjects. The results shown that the sensor performs reliably, being a simple and low-cost solution to the intended application.

  14. Central Bank independence

    Directory of Open Access Journals (Sweden)

    Vasile DEDU

    2012-08-01

    Full Text Available In this paper we present the key aspects regarding central bank’s independence. Most economists consider that the factor which positively influences the efficiency of monetary policy measures is the high independence of the central bank. We determined that the National Bank of Romania (NBR has a high degree of independence. NBR has both goal and instrument independence. We also consider that the hike of NBR’s independence played an important role in the significant disinflation process, as headline inflation dropped inside the targeted band of 3% ± 1 percentage point recently.

  15. Several Centuries of Centrality

    OpenAIRE

    Roth, Dana L.

    2015-01-01

    As Carolyn Bertozzi mentioned in her inaugural editorial, the relationship of “Central Science” to “Chemistry” became popularized over 40 years ago with the publication of the first edition of Brown and LeMay’s Chemistry: The Central Science, now in its 13th edition. Yet as late as 2003, Prof. Sason Shaik at The Hebrew University claimed “popularization of chemistry remains scant.” He goes on to share [his] “own experience of popularizing chemistry by delivering the following universal messag...

  16. Glueballs A central mystery

    CERN Document Server

    Close, Francis Edwin

    2000-01-01

    Glueball candidates and qqbar mesons have been found to be produced with different momentum and angular dependences in the central region of pp collisions. This talk illustrates this phenomenon and explains the phi and t dependences of mesons with JPC = 0++,0-+, 1++, 2++ and 2-+. For production of 0++ and 2++ mesons the analysis reveals a systematic behaviour in the data that appears to distinguish between qqbar and non-qqbar or glueball candidates. An explanation is given for the absence of 0-+ glueball candidates in central production at present energies and the opportunity for their discovery at RHIC is noted.

  17. Results in energy saving obtained with the application of speed variator in fossil power stations; Resultados de ahorro de energia obtenidos con la aplicacion de variadores de velocidad en centrales termoelectricas

    Energy Technology Data Exchange (ETDEWEB)

    Merlos Rueda, Rosa Maria [Programa de Ahorro de Energia del Sector Electrico (PAESE), Mexico, D. F. (Mexico)

    1999-07-01

    The project of installation of speed variator in fossil power stations (CT's) of Comision Federal de Electricidad (CFE), as an energy saving measure, is a pilot project that began with the support of the Subdivision de Generacion, and promoted by the Energy Saving Program of the Electric Sector (PAESE), with the putting in operation of an equipment in the condensate pump of the Punta Prieta II C. T. U3. The energy saving observed was substantial, fluctuating between the 19.4% at high loads (at 90% load) and the 71.1% at low loads (at 40% load) of the generating unit. With these results, it was decided to extend the scope of the project with the installation of 6 more equipment for equal number of fossil power stations, located in 4 of the 5 Regions of Generation. The fossil power stations, selected for this stage of the project were: C. T. Felipe Carrillo Puerto U1, C.T. Lerma U4, C.T. Salamanca U1, C.T. Monterrey U6, C.T. Francisco Villa U3 and the C.T. Punta Prieta II-U1. The equipment was in operation during the first quarter of 1998, and the first results indicate an energy savings average per equipment, between 39% and 52%. The recovery of the investment fluctuates between the 48.4% and the 87.6% in less than two years of operation, with which a maximum period of recovery of 3 years is expected. The estimated potential of energy saving, considering the application of these devices in condensate pumps, feedwater pumps (where no speed variator is installed) forced draft fans, induced draft fans and gas recirculation fans, as well as circulation water pumps, of the existing Generating Power stations, ascends to an annual total of 830,000, which represents an approximate 9.4% of the National consumption of self services. [Spanish] El proyecto de instalacion de variadores de velocidad en Centrales Termoelectricas (CT's) de la Comision Federal de Electricidad (CFE), como medida de ahorro de energia, es un proyecto piloto que se inicio con el apoyo de la

  18. Community centrality and social science research.

    Science.gov (United States)

    Allman, Dan

    2015-12-01

    Community centrality is a growing requirement of social science. The field's research practices are increasingly expected to conform to prescribed relationships with the people studied. Expectations about community centrality influence scholarly activities. These expectations can pressure social scientists to adhere to models of community involvement that are immediate and that include community-based co-investigators, advisory boards, and liaisons. In this context, disregarding community centrality can be interpreted as failure. This paper considers evolving norms about the centrality of community in social science. It problematises community inclusion and discusses concerns about the impact of community centrality on incremental theory development, academic integrity, freedom of speech, and the value of liberal versus communitarian knowledge. Through the application of a constructivist approach, this paper argues that social science in which community is omitted or on the periphery is not failed science, because not all social science requires a community base to make a genuine and valuable contribution. The utility of community centrality is not necessarily universal across all social science pursuits. The practices of knowing within social science disciplines may be difficult to transfer to a community. These practices of knowing require degrees of specialisation and interest that not all communities may want or have.

  19. Application of central venous catheter in hemodialysis in 2 000 cases%中心静脉导管在血液净化中的临床应用

    Institute of Scientific and Technical Information of China (English)

    徐晨; 黄静; 李艳春; 刘婧; 申珅

    2014-01-01

    目的 通过观察中心静脉长期、临时留置导管在血液透析中使用状况,探讨中心静脉导管相关并发症及处理方法,改善血液透析患者预后.方法 回顾性分析2 000例使用中心静脉长期、临时置管维持性血液透析患者的临床资料.其中500例为长期双腔导管,1 500例为临时双腔导管,分析中心静脉导管的相关并发症与处理效果.结果 置管过程中的常见并发症有:误穿动脉11例(0.55%)、皮下血肿6例(0.3%).导管留置并发症有:血流量不足24例(1.2%),导管相关感染23例(1.15%),穿刺部位渗血15例(0.75%),导管意外脱落3例(0.15%).以上并发症均在给予相应的处理后痊愈,未留下相关后遗症.结论 中心静脉导管相关并发症值得临床重视,提高置管技术,加强导管使用维护,及时处理是防范导管失功能的关键.%Objective To discuss the complications and treatment of applying central venous catheter in hemodialysis by observing its application condition.Methods The clinical data of 2 000 patients with centralvenous catheter applied in hemodialysis were enrolled and analyzed retrospectively including 500 cases of long-term duallumen catheters and 1 500 cases of temporary duallumen catheters.The related complications and treatments were analyzed.Results The common complications occurred during catheterizations included inadvertent arterial puncture in 11 cases (0.55%) and ecchymoma in 6 cases (0.3%),while the complications of catheterizations included inadequate blood flow in 24 cases (1.2%),catheter related infection in 23 cases (1.15%),local bleeding in 15 cases (0.75%) and catheter inadvertent withdrawal in 3 cases(0.15%).Above complications were recovered without recurrences after taking corresponding treatments.Conclusion Attention should be paid to the central venous catheter related complications.Improving technology,strengthening nursing care and taking timely treatment are the key

  20. A History of the Central Limit Theorem

    CERN Document Server

    Fischer, Hans

    2011-01-01

    This study discusses the history of the central limit theorem and related probabilistic limit theorems from about 1810 through 1950. In this context the book also describes the historical development of analytical probability theory and its tools, such as characteristic functions or moments. The central limit theorem was originally deduced by Laplace as a statement about approximations for the distributions of sums of independent random variables within the framework of classical probability, which focused upon specific problems and applications. Making this theorem an autonomous mathematical

  1. Retiring the central executive.

    Science.gov (United States)

    Logie, Robert H

    2016-10-01

    Reasoning, problem solving, comprehension, learning and retrieval, inhibition, switching, updating, or multitasking are often referred to as higher cognition, thought to require control processes or the use of a central executive. However, the concept of an executive controller begs the question of what is controlling the controller and so on, leading to an infinite hierarchy of executives or "homunculi". In what is now a QJEP citation classic, Baddeley [Baddeley, A. D. (1996). Exploring the central executive. Quarterly Journal of Experimental Psychology, 49A, 5-28] referred to the concept of a central executive in cognition as a "conceptual ragbag" that acted as a placeholder umbrella term for aspects of cognition that are complex, were poorly understood at the time, and most likely involve several different cognitive functions working in concert. He suggested that with systematic empirical research, advances in understanding might progress sufficiently to allow the executive concept to be "sacked". This article offers an overview of the 1996 article and of some subsequent systematic research and argues that after two decades of research, there is sufficient advance in understanding to suggest that executive control might arise from the interaction among multiple different functions in cognition that use different, but overlapping, brain networks. The article concludes that the central executive concept might now be offered a dignified retirement.

  2. Central Nervous System Tuberculosis

    OpenAIRE

    Bano, Shahina; Chaudhary, Vikas; Yadav, Sachchidanand

    2012-01-01

    Central nervous system tuberculosis is a rare presentation of active tuberculosis and accounts for about 1% of cases (1). The three clinical categories include meningitis, intracranial tuberculomas, and spinal tuberculous arachnoiditis. We report a case of a young man who presented with active pulmonary tuberculosis in addition to tuberculous meningitis and the presence of numerous intracranial tuberculomas.

  3. Central venous line - infants

    Science.gov (United States)

    A central venous line (CVL) is a long, soft, plastic tube that is put into a large vein in the chest. WHY IS A CVL USED? A CVL is often put in when a baby cannot get a ... (MCC). A CVL can be used to give nutrients or medicines to a ...

  4. CMS Central Hadron Calorimeter

    OpenAIRE

    Budd, Howard S.

    2001-01-01

    We present a description of the CMS central hadron calorimeter. We describe the production of the 1996 CMS hadron testbeam module. We show the results of the quality control tests of the testbeam module. We present some results of the 1995 CMS hadron testbeam.

  5. Ecodesign in Central America

    NARCIS (Netherlands)

    Crul, M.R.M.

    2003-01-01

    This PhD thesis describes and analyses the change process started by the Ecodesign project in Central America, executed between 1998 and 2002. The project started using the concept and praxis developed in Europe. Nine ecodesign projects were performed in industry, and ecodesign was introduced to cou

  6. Central nervous system tuberculosis.

    Science.gov (United States)

    Torres, Carlos; Riascos, Roy; Figueroa, Ramon; Gupta, Rakesh K

    2014-06-01

    Tuberculosis (TB) has shown a resurgence in nonendemic populations in recent years and accounts for 8 million deaths annually in the world. Central nervous system involvement is one of the most serious forms of this infection, acting as a prominent cause of morbidity and mortality in developing countries. The rising number of cases in developed countries is mostly attributed to factors such as the pandemic of acquired immunodeficiency syndrome and increased migration in a globalized world. Mycobacterium TB is responsible for almost all cases of tubercular infection in the central nervous system. It can manifest in a variety of forms as tuberculous meningitis, tuberculoma, and tubercular abscess. Spinal infection may result in spondylitis, arachnoiditis, and/or focal intramedullary tuberculomas. Timely diagnosis of central nervous system TB is paramount for the early institution of appropriate therapy, because delayed treatment is associated with severe morbidity and mortality. It is therefore important that physicians and radiologists understand the characteristic patterns, distribution, and imaging manifestations of TB in the central nervous system. Magnetic resonance imaging is considered the imaging modality of choice for the study of patients with suspected TB. Advanced imaging techniques including magnetic resonance perfusion and diffusion tensor imaging may be of value in the objective assessment of therapy and to guide the physician in the modulation of therapy in these patients.

  7. Central Dogma Goes Digital.

    Science.gov (United States)

    Lin, Yihan; Elowitz, Michael B

    2016-03-17

    In this issue of Molecular Cell, Tay and colleagues (Albayrak et al., 2016) describe a new technique to digitally quantify the numbers of protein and mRNA in the same mammalian cell, providing a new way to look at the central dogma of molecular biology.

  8. Multicultural Central Asia.

    Science.gov (United States)

    Boyle, Eric D.

    This article addresses the multicultural aspect of Central Asia in response to the discussion on diversity in U.S. classrooms. Many areas of the world are more diverse than the U.S., and these areas experience successes and failures with many of the same issues the U.S. is currently struggling with. Comparing the U.S. diversity debate with similar…

  9. Channeling the Central Dogma.

    Science.gov (United States)

    Calabrese, Ronald L

    2014-05-21

    How do neurons and networks achieve their characteristic electrical activity, regulate this activity homeostatically, and yet show population variability in expression? In this issue of Neuron, O'Leary et al. (2014) address some of these thorny questions in this theoretical analysis that starts with the Central Dogma.

  10. Company activities - central region

    Energy Technology Data Exchange (ETDEWEB)

    Ayling, G.

    2007-06-15

    The first section of the article gives an overview of exploration and new developments in the field of gold, nickel, diamond and opal mining in central Queensland. The second part looks at coal, coal seam gas and petroleum exploration and development projects in the area. 1 fig.

  11. Testing for central symmetry

    NARCIS (Netherlands)

    Einmahl, John; Gan, Zhuojiong

    2016-01-01

    Omnibus tests for central symmetry of a bivariate probability distribution are proposed. The test statistics compare empirical measures of opposite regions. Under rather weak conditions, we establish the asymptotic distribution of the test statistics under the null hypothesis; it follows that they a

  12. Central areolar choroidal dystrophy.

    NARCIS (Netherlands)

    Boon, C.J.F.; Klevering, B.J.; Cremers, F.P.M.; Zonneveld-Vrieling, M.N.; Theelen, T.; Hollander, A.I. den; Hoyng, C.B.

    2009-01-01

    OBJECTIVE: To describe the clinical characteristics, follow-up data and molecular genetic background in a large group of patients with central areolar choroidal dystrophy (CACD). DESIGN: Retrospective case series study. PARTICIPANTS: One hundred three patients with CACD from the Netherlands. METHODS

  13. Induced, endogenous and exogenous centrality

    OpenAIRE

    Everett, Martin G.; Stephen P. Borgatti

    2010-01-01

    Centrality measures are based upon the structural position an actor has within the network. Induced centrality, sometimes called vitality measures, take graph invariants as an overall measure and derive vertex level measures by deleting individual nodes or edges and examining the overall change. By taking the sum of standard centrality measures as the graph invariant we can obtain measures which examine how much centrality an individual node contributes to the centrality of the other nodes in...

  14. Do Central Banks Need Capital?

    OpenAIRE

    Peter Stella

    1997-01-01

    Central banks may operate perfectly well without capital as conventionally defined. A large negative net worth, however, is likely to compromise central bank independence and interfere with its ability to attain policy objectives. If society values an independent central bank capable of effectively implementing monetary policy, recapitalization may become essential. Proper accounting practice in determining central bank profit or loss and rules governing the transfer of the central bank’s ope...

  15. 中心性指标在开放存取期刊评价中的适用性研究%Research on the Applicability of Centrality Indexes to Evaluate Open Access Journals

    Institute of Scientific and Technical Information of China (English)

    王智博; 盛小平

    2014-01-01

    By collecting the open access journals of health science which are from Directory of Open Access Journals and recorded both in SCImago Journal Rank ( SJR) and Journal Citation Reports ( JCR ) , this paper constructs citation matrix of OA journals, calculates the centrality index of each journal by use of UCINET soft, and does correlation analysis between the centrality index and the SJR index.It is found that in degree centrality can be an index to evaluate OA journals, and that degree centrality and mid centrality can be used to evaluate OA journals only with other indexes, but that out degree centrality and closeness centrality can't be used as indicators to evaluate quality of OA journals.%通过采集同被期刊引用报告(JCR)和SCImago期刊排名(SJR)收录的来源于开放存取期刊目录的医学开放存取期刊,构建开放存取期刊引文网络矩阵,使用UCINET软件计算这些开放存取期刊的中心性指数,并将它们与SJR指数进行相关性分析,发现入度中心度可作为开放存取期刊评价的指标,而点度中心度和中间中心度需与其他指标联合使用才能评价开放存取期刊,出度中心度和接近中心度不适宜作为开放存取期刊质量评价指标。

  16. 应用心房内心电图辅助PICC导管尖端定位的效果评价%The clinical application of intraatrial electrocardiogram-assisted Peripherally lnserted Central Catheter tip positioning technology

    Institute of Scientific and Technical Information of China (English)

    姜桂春

    2016-01-01

    目的:评价心房内心电图辅助PICC导管尖端定位的临床应用效果。方法:将我院2015年1-9月入院的1000例患者按抽签法随机分为对照组和实验组,两组均采用常规方法进行导管置入,两组患者在置管结束后均进行X线片定位确定导管尖端位置,而实验组在置管过程中增加应用心房内心电图辅助技术进行导管尖端定位,比较两组导管尖端的异位率及导管尖端位于理想位置的比例。结果:实验组导管尖端异位率比对照组低(χ2=30.548,P<0.001);不同置管静脉中两组导管尖端异位率均存在统计学差异(P<0.05);实验组导管尖端位于理想位置的比例高于对照组(P<0.05)。结论:应用心房内心电图辅助PICC导管尖端定位,可有效降低导管尖端的异位率,在判断导管尖端位于理想位置的灵敏度高。%Objective: To explore the clinical application of intraatrial electrocardiogram-assisted Peripherally lnserted Central Catheter (PICC) tip positioning technology. Methods: Totally 1000 hospitalized patients were recruited from January 2015 to September and randomly divided into the control group and the experimental group by random sampling method. The patients in two groups were catheterized using conventional method and the catheter tip position were determined by X-rays, while the experimental group added intra-atrial electrocardiogram assisted PICC tip positioning technology to position catheter tip. We compared the catheter heterotopia rate and the sensitivity of catheter tip located in the superior vena cava between the two groups. Results: The catheter heterotopia rate in the experimental group was signiifcantly lower than that in the control group (2= 30.548,P<0.001), while the sensitivity of catheter tip located in the superior vena cava had signiifcant difference (P<0.05). Conclusion: The application of intraatrial electrocardiogram-assisted PICC tip positioning

  17. Dry needling - peripheral and central considerations.

    Science.gov (United States)

    Dommerholt, Jan

    2011-11-01

    Dry needling is a common treatment technique in orthopedic manual physical therapy. Although various dry needling approaches exist, the more common and best supported approach targets myofascial trigger points. This article aims to place trigger point dry needling within the context of pain sciences. From a pain science perspective, trigger points are constant sources of peripheral nociceptive input leading to peripheral and central sensitization. Dry needling cannot only reverse some aspects of central sensitization, it reduces local and referred pain, improves range of motion and muscle activation pattern, and alters the chemical environment of trigger points. Trigger point dry needling should be based on a thorough understanding of the scientific background of trigger points, the differences and similarities between active and latent trigger points, motor adaptation, and central sensitize application. Several outcome studies are included, as well as comments on dry needling and acupuncture.

  18. Central simple Poisson algebras

    Institute of Scientific and Technical Information of China (English)

    SU Yucai; XU Xiaoping

    2004-01-01

    Poisson algebras are fundamental algebraic structures in physics and symplectic geometry. However, the structure theory of Poisson algebras has not been well developed. In this paper, we determine the structure of the central simple Poisson algebras related to locally finite derivations, over an algebraically closed field of characteristic zero.The Lie algebra structures of these Poisson algebras are in general not finitely-graded.

  19. Central corneal abscess.

    Science.gov (United States)

    van Bijsterveld, O P

    1976-05-01

    Central corneal abscess developed in the experimental animal after inoculation of biologically active staphylococcal strains in a paracentral epithelial lesion of the cornea. These abscesses did not ulcerate, developed only with high inocula, occurred more frequently in immunized rabbits. A serpiginous type of ulceration did not develop at the site of the initial epithelial lesion nor at any other place in the cornea. Histologically, the lesions consisted of densely packed polymorphonuclear leukocytes between the corneal lamellae.

  20. FNAL central email systems

    Energy Technology Data Exchange (ETDEWEB)

    Schmidt, Jack; Lilianstrom, Al; Pasetes, Ray; Hill, Kevin; /Fermilab

    2004-10-01

    The FNAL Email System is the primary point of entry for email destined for an employee or user at Fermilab. This centrally supported system is designed for reliability and availability. It uses multiple layers of protection to help ensure that: (1) SPAM messages are tagged properly; (2) All mail is inspected for viruses; and (3) Valid mail gets delivered. This system employs numerous redundant subsystems to accomplish these tasks.

  1. Centrality Measures in Networks

    CERN Document Server

    Bloch, Francis; Tebaldi, Pietro

    2016-01-01

    We show that although the prominent centrality measures in network analysis make use of different information about nodes' positions, they all process that information in an identical way: they all spring from a common family that are characterized by the same simple axioms. In particular, they are all based on a monotonic and additively separable treatment of a statistic that captures a node's position in the network.

  2. Central core disease

    Directory of Open Access Journals (Sweden)

    Jungbluth Heinz

    2007-05-01

    Full Text Available Abstract Central core disease (CCD is an inherited neuromuscular disorder characterised by central cores on muscle biopsy and clinical features of a congenital myopathy. Prevalence is unknown but the condition is probably more common than other congenital myopathies. CCD typically presents in infancy with hypotonia and motor developmental delay and is characterized by predominantly proximal weakness pronounced in the hip girdle; orthopaedic complications are common and malignant hyperthermia susceptibility (MHS is a frequent complication. CCD and MHS are allelic conditions both due to (predominantly dominant mutations in the skeletal muscle ryanodine receptor (RYR1 gene, encoding the principal skeletal muscle sarcoplasmic reticulum calcium release channel (RyR1. Altered excitability and/or changes in calcium homeostasis within muscle cells due to mutation-induced conformational changes of the RyR protein are considered the main pathogenetic mechanism(s. The diagnosis of CCD is based on the presence of suggestive clinical features and central cores on muscle biopsy; muscle MRI may show a characteristic pattern of selective muscle involvement and aid the diagnosis in cases with equivocal histopathological findings. Mutational analysis of the RYR1 gene may provide genetic confirmation of the diagnosis. Management is mainly supportive and has to anticipate susceptibility to potentially life-threatening reactions to general anaesthesia. Further evaluation of the underlying molecular mechanisms may provide the basis for future rational pharmacological treatment. In the majority of patients, weakness is static or only slowly progressive, with a favourable long-term outcome.

  3. West and Central Africa.

    Science.gov (United States)

    Lydie, N; Robinson, N J

    1998-01-01

    This article reviews scientific and other literature during the 1990s that links migration and mobility with the spread of sexually transmitted diseases (STDs), including HIV/AIDS. The focus is on key population groups linked to the spread of HIV and STDs in West and Central Africa: migrant laborers, truck drivers, itinerant traders, commercial sex workers (CSWs), and refugees. Countries with high emigration and immigration tend to have high levels of HIV infection, with the exception of Senegal. The main destination of immigrants are Senegal, Nigeria, and Cote d'Ivoire in West Africa and Cameroon, Congo, Gabon, and Congo in Central Africa. The risk of infection and the spread of HIV is variable among migrants. There is little in the literature that substantiates hypotheses about the strong association between migration and HIV-positive status. Information is needed on the duration, frequency of return visits, living conditions, sexual activities with multiple partners, and information before departure, along the routes, at final destination, and at the time of returns. Action-based research in five West African countries (Burkina Faso, Cote d'Ivoire, Mali, Niger, and Senegal) should produce results in late 1998. Comparable studies in Central Africa are unknown. Regional studies should be complemented by local studies. Prevention would benefit from studies on the relative size of these five population groups by geographic location.

  4. Application de la systémique à la conception d'un modèle de conduite en mode dégradé d'une centrale nucléaire

    OpenAIRE

    Millerat, Pierre; Chaillot, Mathias; Ermine, Jean-Louis

    1996-01-01

    International audience; Cette publication présente un modèle de conduite d'une centrale nucléaire en mode dégradé fondé sur l'élaboration conjointe de trois modèles. Le premier décrit l'ensemble des phénomènes physiques pertinents pour le pilotage d'une centrale nucléaire, le second l'ensemble des activités de conduite d'un opérateur, le troisième une procédure de conduite en mode dégradé d'une centrale nucléaire. La finalité de ce modèle est d'expliquer à un opérateur cette conduite....

  5. Central African Republic.

    Science.gov (United States)

    1986-02-01

    Focus in this discussion of the Central African Republic is on: geography; the people; history and political conditions; government; the economy; foreign relations; and relations with the US. The population of the Central African Republic totaled 2.7 million in 1985 with an annual growth rate of 2.8%. The infant mortality rate is 134/1000 with life expectancy at 49 years. The Central African Republic is at almost the precise center of Africa, about 640 km from the nearest ocean. More than 70% of the population live in rural areas. There are more than 80 ethnic groups, each with its own language. The precolonial history of the area was marked by successive waves of migration, of which little is known. These migrations are responsible for the complex ethnic and linguistic patterns today. United with Chad in 1906, it formed the Oubangui-Chari-Chad colony. In 1910, it became 1 of the 4 territories of the Federation of French Equatorial Africa, along with Chad, Congo, and Gabon. After World War II, the French Constitution of 1946 inaugurated the first of a series of reforms that led eventually to complete independence for all French territories in western and equatorial Africa. The nation became an autonomous republic within the newly established French Community on December 1, 1958, and acceded to complete independence as the Central Africa Republic on August 13, 1960. The government is made up of the executive and the judicial branches. The constitution and legislature remain suspended. All executive and legislative powers, as well as judicial oversight, are vested in the chief of state. The Central African Republic is 1 of the world's least developed countries, with an annual per capita income of $310. 85% of the population is engaged in subsistence farming. Diamonds account for nearly 1/3 of export earnings; the industrial sector is limited. The US terminated bilateral assistance programs in 1979, due to the human rights violations of the Bokassa regime, but modest

  6. Exploration of biological network centralities with CentiBiN

    Directory of Open Access Journals (Sweden)

    Schreiber Falk

    2006-04-01

    Full Text Available Abstract Background The elucidation of whole-cell regulatory, metabolic, interaction and other biological networks generates the need for a meaningful ranking of network elements. Centrality analysis ranks network elements according to their importance within the network structure and different centrality measures focus on different importance concepts. Central elements of biological networks have been found to be, for example, essential for viability. Results CentiBiN (Centralities in Biological Networks is a tool for the computation and exploration of centralities in biological networks such as protein-protein interaction networks. It computes 17 different centralities for directed or undirected networks, ranging from local measures, that is, measures that only consider the direct neighbourhood of a network element, to global measures. CentiBiN supports the exploration of the centrality distribution by visualising central elements within the network and provides several layout mechanisms for the automatic generation of graphical representations of a network. It supports different input formats, especially for biological networks, and the export of the computed centralities to other tools. Conclusion CentiBiN helps systems biology researchers to identify crucial elements of biological networks. CentiBiN including a user guide and example data sets is available free of charge at http://centibin.ipk-gatersleben.de/. CentiBiN is available in two different versions: a Java Web Start application and an installable Windows application.

  7. Spherical explosion with central energy source

    CERN Document Server

    Masuyama, Miyu; Tsuboki, Yoichiro

    2015-01-01

    We present a novel semi-analytic solution describing the propagation of a spherical blast wave driven by a central energy source. The initial density profile has a power-law function of the distance from the center and the energy is injected only into the central region at a rate given by a power-law function of time. This solution is composed of three regions separated by the contact surface and the shock front. The innermost region is assumed to be uniform and the outside of the contact surface includes the shocked matter described by self-similar solutions. We analytically derive the applicable range of parameters of this solution from requirements to satisfy boundary conditions. We perform numerical simulations for flows with various values of parameters, some of which reside out of the thus derived applicable range, and compare with the semi-analytic solutions.

  8. 集中型健康教育模式在NICU低收入家长教育中的应用%Application of centralized health education model among low-income parents in NICU

    Institute of Scientific and Technical Information of China (English)

    刘淑娟; 魏雪; 曹军华; 郝祥梅

    2015-01-01

    目的:探讨集中型健康教育模式在新生儿重症监护室( NICU)低收入家长教育中的应用效果。方法将2012年12月—2013年6月收治的NICU低收入家长200名,按患儿住院顺序随机分为观察组(100名)和对照组(100名),对照组低收入家长采用常规健康教育模式,观察组采用常规健康教育模式的基础上采用集中型健康教育。采用自制健康教育效果评价表和自觉遵医行为表及医院统一的护理满意度问卷评价两组研究对象健康教育知识知晓状况、遵医行为及护理满意度。结果观察组满意度为97.0%,高于对照组84.0%,两组比较差异有统计学意义(χ2=9.83;P<0.01);观察组家长健康教育知识掌握情况优于对照组,差异有统计学意义(P<0.05);观察组家长遵医行为情况:治疗情况为92.0%,配合检查为95.0%,按时缴费为100.0%,探陪制度为90.0%,均高于对照组,两组比较差异有统计学意义(χ2值分别为20.37,20.41,18.58,14.59;P<0.01)。结论集中型健康教育的实施促进了NICU低收入家长对健康知识的掌握,对健康教育满意度增加,遵医行为增强,可作为NICU低收入家长健康教育模式推广。%Objective To investigate the application effect of centralized health education among low-income parents in neonatal intensive care unit ( NICU) . Methods A total of 200 cases, who had low income parents and admitted to NICU from December 2012 to June 2013, were randomly divided into observation group (100 cases) and control group (100 cases). The neonatus in the control group underwent conventional health education mode, while neonatus in the observation group received conventional health education model based on a new type of health education on adoption. The awareness of health education, medical compliance and satisfaction of nursing assessed by self-designed health education effect scale, self-realization medical compliance and the satisfaction questionnaire in our

  9. Central venous catheter - dressing change

    Science.gov (United States)

    ... during cancer treatment Bone marrow transplant - discharge Central venous catheter - flushing Peripherally inserted central catheter - flushing Sterile technique Surgical wound care - open Review Date 9/17/2016 Updated by: ...

  10. Central effects of fingolimod.

    Science.gov (United States)

    Cruz, Vítor T; Fonseca, Joaquim

    2014-08-01

    Introduccion. El fingolimod, un modulador del receptor de la esfingosina-1-fosfato (S1P) dotado de un mecanismo de accion novedoso, fue el primer tratamiento oral aprobado para la esclerosis multiple remitente recurrente. Su union a los receptores S1P1 de los linfocitos promueve la retencion selectiva de los linfocitos T virgenes y de memoria central en los tejidos linfoides secundarios, lo que impide su salida hacia el sistema nervioso central (SNC). Asimismo, el fingolimod atraviesa con facilidad la barrera hematoencefalica, y diversos estudios le atribuyen un efecto neuroprotector directo en el SNC. Objetivo. Revisar la informacion disponible acerca de los efectos centrales del fingolimod. Desarrollo. El desequilibrio entre los procesos lesivos y reparadores constituye un reflejo de la desmielinizacion cronica, la degeneracion axonal y la gliosis, y parece contribuir a la discapacidad que la esclerosis multiple acarrea. La facilidad con la que el fingolimod atraviesa la barrera hematoencefalica le permite actuar directamente sobre los receptores S1P localizados en las celulas del SNC. Una vez en el interior del SNC, ocupa los receptores S1P de los oligodendrocitos y de sus celulas precursoras, de los astrocitos, los microgliocitos y las neuronas, fomentando la remielinizacion, la neuroproteccion y los procesos endogenos de regeneracion. La eficacia evidenciada en los ensayos clinicos concuerda con un mecanismo de accion que incluiria efectos directos sobre las celulas del SNC. Conclusiones. Los datos disponibles indican que la eficacia del fingolimod en el tratamiento de la esclerosis multiple se debe a su ambivalencia como molecula inmunomoduladora y moduladora directa de los receptores S1P del SNC. Tanto es asi que estudios recientes le atribuyen efectos neuroprotectores en varios modelos que suscitan expectativas en torno a su posible aplicacion terapeutica en la enfermedad de Alzheimer, el paludismo cerebral y el neuroblastoma, asi como en la neuroproteccion

  11. Research and application of tight oil reservoir fracturing fluid in Shaxi Temple layer of Central Sichuan%川中沙溪庙致密油藏压裂液技术研究及应用

    Institute of Scientific and Technical Information of China (English)

    孙川; 刘友权; 熊颖; 郑凯; 吴文刚; 陈鹏飞; 张倩

    2014-01-01

    川中沙溪庙致密油藏为特低孔、低渗致密储层,压裂工艺要求先以滑溜水大排量泵注方式在地层中形成复杂缝网,再以冻胶压裂液造主缝,形成大规模的连通性体积缝网。将聚丙烯酰胺类滑溜水与低分子量胍胶类冻胶压裂液复合应用,开发出了适合川中沙溪庙储层的“滑溜水+冻胶”混合压裂液技术。其中,滑溜水具有低摩阻、高效防膨等特点;冻胶压裂液具有耐剪切、低伤害等特点;混合压裂液体系的破乳效果好、返排能力强。现场试验表明:“滑溜水+冻胶”混合压裂液技术具有良好的储层改造效果,在G36井、G117井应用获得成功,现场降阻率达61.5%~64.8%、返排率>40%,返排液油水界面清晰,获井口测试产油45.1 t/d。%The tight reservoir of Sichuan Shaxi Temple layer has characteristics of extremely low porosity and low permeability ,and the fracturing process requires to pump slickwater with large emission to form complex fracture networks in formation ,then pump gel fracturing fluid to create main fracture and form a large volume of connective fracture network .Due to the compos-ite application of polyacrylamide slickwater and low molecular guar gum fracturing fluid ,a mixed fracturing fluid technology of “slickwater + crosslinked gel” has been developed ,which is suit-able to Shaxi Temple reservoir in Central Sichuan .Slickwater has characteristics of low friction and high clay stable performance , crosslinked fracturing fluid has characteristics of excellent shear resistance and low core damage ,and the mixed fracturing fluid has good demulsification performance and high flowback rate .Field test results show that “slickwater + crosslinked gel”technology has good effect of reservoir stimulation ,which was successful applied in G36 well , G117 well ,the drag reduction rate reached 61 .5% ~64 .8% ,flowback rate was more than 40% , interface of

  12. 3D CENTRAL LINE EXTRACTION OF FOSSIL OYSTER SHELLS

    Directory of Open Access Journals (Sweden)

    A. Djuricic

    2016-06-01

    Full Text Available Photogrammetry provides a powerful tool to digitally document protected, inaccessible, and rare fossils. This saves manpower in relation to current documentation practice and makes the fragile specimens more available for paleontological analysis and public education. In this study, high resolution orthophoto (0.5 mm and digital surface models (1 mm are used to define fossil boundaries that are then used as an input to automatically extract fossil length information via central lines. In general, central lines are widely used in geosciences as they ease observation, monitoring and evaluation of object dimensions. Here, the 3D central lines are used in a novel paleontological context to study fossilized oyster shells with photogrammetric and LiDAR-obtained 3D point cloud data. 3D central lines of 1121 Crassostrea gryphoides oysters of various shapes and sizes were computed in the study. Central line calculation included: i Delaunay triangulation between the fossil shell boundary points and formation of the Voronoi diagram; ii extraction of Voronoi vertices and construction of a connected graph tree from them; iii reduction of the graph to the longest possible central line via Dijkstra’s algorithm; iv extension of longest central line to the shell boundary and smoothing by an adjustment of cubic spline curve; and v integration of the central line into the corresponding 3D point cloud. The resulting longest path estimate for the 3D central line is a size parameter that can be applied in oyster shell age determination both in paleontological and biological applications. Our investigation evaluates ability and performance of the central line method to measure shell sizes accurately by comparing automatically extracted central lines with manually collected reference data used in paleontological analysis. Our results show that the automatically obtained central line length overestimated the manually collected reference by 1.5% in the test set, which

  13. D Central Line Extraction of Fossil Oyster Shells

    Science.gov (United States)

    Djuricic, A.; Puttonen, E.; Harzhauser, M.; Mandic, O.; Székely, B.; Pfeifer, N.

    2016-06-01

    Photogrammetry provides a powerful tool to digitally document protected, inaccessible, and rare fossils. This saves manpower in relation to current documentation practice and makes the fragile specimens more available for paleontological analysis and public education. In this study, high resolution orthophoto (0.5 mm) and digital surface models (1 mm) are used to define fossil boundaries that are then used as an input to automatically extract fossil length information via central lines. In general, central lines are widely used in geosciences as they ease observation, monitoring and evaluation of object dimensions. Here, the 3D central lines are used in a novel paleontological context to study fossilized oyster shells with photogrammetric and LiDAR-obtained 3D point cloud data. 3D central lines of 1121 Crassostrea gryphoides oysters of various shapes and sizes were computed in the study. Central line calculation included: i) Delaunay triangulation between the fossil shell boundary points and formation of the Voronoi diagram; ii) extraction of Voronoi vertices and construction of a connected graph tree from them; iii) reduction of the graph to the longest possible central line via Dijkstra's algorithm; iv) extension of longest central line to the shell boundary and smoothing by an adjustment of cubic spline curve; and v) integration of the central line into the corresponding 3D point cloud. The resulting longest path estimate for the 3D central line is a size parameter that can be applied in oyster shell age determination both in paleontological and biological applications. Our investigation evaluates ability and performance of the central line method to measure shell sizes accurately by comparing automatically extracted central lines with manually collected reference data used in paleontological analysis. Our results show that the automatically obtained central line length overestimated the manually collected reference by 1.5% in the test set, which is deemed

  14. Central osteosclerosis with trichothiodystrophy

    Energy Technology Data Exchange (ETDEWEB)

    Wakeling, Emma L.; Brady, Angela F. [North West Thames Regional Genetics Service, Kennedy-Galton Centre, Level 8 V, North West London Hospitals NHS Trust, Watford Road, HAI 3UJ, Harrow, Middlesex (United Kingdom); Cruwys, Michele [Department of Paediatrics, Hillingdon Hospital, Hillingdon, Middlesex (United Kingdom); Suri, Mohnish [Clinical Genetics Service, City Hospital, Nottingham (United Kingdom); Aylett, Sarah E. [Neurosciences Unit, Great Ormond Street Hospital for Children NHS Trust, London (United Kingdom); Hall, Christine [Department of Radiology, Great Ormond Street Hospital for Children NHS Trust, London (United Kingdom)

    2004-07-01

    Trichothiodystrophy (TTD) is a rare, autosomal recessive, multisystem disorder associated with defects in nucleotide excision repair. We report a 7-year-old boy with TTD due to mutation in the XPD gene. The patient has classic features of this condition, including brittle, sulphur-deficient hair, ichthyosis, growth retardation and developmental delay. In addition, he has radiological evidence of progressive central osteosclerosis. Although similar radiological findings have previously been reported in a small number of patients, this association is not widely recognised. We review the radiological findings in this and other similar cases and discuss the natural history of these bony changes. (orig.)

  15. Centralized vs. De-centralized Multinationals and Taxes

    DEFF Research Database (Denmark)

    Nielsen, Søren Bo; Raimondos-Møller, Pascalis; Schjelderup, Guttorm

    2005-01-01

    The paper examines how country tax differences affect a multinational enterprise's choice to centralize or de-centralize its decision structure. Within a simple model that emphasizes the multiple conflicting roles of transfer prices in MNEs - here, as a strategic pre-commitment device and a tax...... manipulation instrument -, we show that (de-)centralized decisions are more profitable when tax differentials are (small) large.Keywords: Centralized vs. de-centralized decisions, taxes, MNEs.JEL-Classification: H25, F23, L23....

  16. Application of General- sub Account Mode in Fund Centralized Management in Enterprise Group%企业集团资金集中管理总分账户模式的应用

    Institute of Scientific and Technical Information of China (English)

    邓群伟

    2012-01-01

    Fund centralized management can improve fund management capacity, heighten fund service eflqciency, which has become the main trend of fund management in enterprise group. Through comparative analysis of fund centralized management mode, we have come to the conclusion that generalsub account mode meets necessary requirement of development of fund centralized management in giant enterprise group. We studied cause, principle, operation mode and special features of fund centralized management in the process of implementation of fund centralized management in giant enterprise group, taking financial corporation as the plat, depending on business bank network system, in terms of innovation mode of general sub account.%资金集中管理,可以增强资金管理能力,提高资金使用效率,目前已经成为企业集团资金管理的主流方式。通过对资金集中管理模式的比较分析,得出总分账户模式是适应特大型企业集团资金集中管理发展必然要求的结论。探讨特大型企业集团在实施资金集中管理过程中,以财务公司为平台,依托商业银行网络系统,借助总分账户这一创新模式进行资金集中管理的成因、原理、运行方式及特点。提出进一步完善总分账户模式的建议。

  17. The application of Shuxuening injection in preventing central venous catheter obstruction%舒血宁注射液在预防中心静脉导管堵塞中的应用

    Institute of Scientific and Technical Information of China (English)

    曾洁仪; 汪敏; 钟淑芬

    2016-01-01

    Objective To investigate the effect of Shuxuening injection on prevention of plugging of central venous catheter. Methods The patients were from Intensive Care Unit through July 2013 and June 2015 and a total of 134 cases of indwelling central venous catheter were included for a prospective study. Of them, 65 cases were treated with Shuxuening injection 20 ml daily through intravenous infusion for two weeks (observation group), 69 cases (control group) received routine care. The incidence of central venous plugging was compared between the two groups. Results The incidence of central venous catheter plugging in the observation group was significantly lower than that of control group (P<0.05). Conclusion Shuxuening injection minimized central venous catheter plugging.%目的:观察舒血宁注射液对预防中心静脉留置导管堵管的应用效果。方法病例选自我科2013年7月~2015年6月留置中心静脉导管患者134例,随机分成2组,对照组给予常规护理,观察组在给予常规护理的基础上加用舒血宁注射液每天20 mL 静脉滴注,疗程为2周,比较2组中心静脉堵管发生率。结果观察组中心静脉留置导管堵管发生率低于对照组,2组具有显著性差异(P<0.05)。结论静脉滴注舒血宁注射液可降低中心静脉导管堵管发生率。

  18. Application effect of measuring central venous pressure with different catheter in LBWIs%不同置管方式测量中心静脉压在低出生体重儿中的应用效果

    Institute of Scientific and Technical Information of China (English)

    郝祥梅; 蔡盈; 刘淑娟; 魏雪; 许燕

    2016-01-01

    Objective To discuss the effect of measuring central venous with peripherally inserted central catheter (PICC) in low birth weight infants (LBWIs).Methods Totally 100 LBWIs admitted in the intensive care unit ( ICU) of a tertiary hospital from January to Octomber 2015 were selected and were randomly divided into the PICC group and the central venous catheterization ( CVC) group, with 50 cases in each group. Patients in the PICC group received the main intravenous catheter, while patients in the CVC group received subclavian intravenous catheter. Data were collected for statistical analysis. The difference of central venous pressure and the incidence rate of complications in patients with different measure methods were compared between two groups.Results The central venous pressure of LBWIs in the PICC group was (8.26±2.18) cmH2O, and in the CVC group was (7.85±2.36) cmH2O (t=0.421,P>0.05); the incidence rates of catheter obstruction, phlebitis and puncture point bleeding of the PICC group were lower than that of the CVC group (χ2=5.01,6.93, 4.00;P0.05);PICC组导管堵管、静脉炎及穿刺点渗血发生率均低于CVC组,差异有统计学意义(χ2值分别为5.01,6.93,4.00;P<0.05);结论低出生体重患儿经PICC导管测量中心静脉压不会影响测量结果,可以减少极低出生体重患儿中心静脉置管并发症的发生,可以推广应用。

  19. Central centrifugal cicatricial alopecia.

    Science.gov (United States)

    Whiting, David A; Olsen, Elise A

    2008-01-01

    A progressive scarring alopecia of the central scalp is commonly seen in young to middle-aged females of African descent. It usually starts at the vertex or mid top of the scalp and gradually spreads centrifugally, hence, the unifying term of central centrifugal cicatricial alopecia. The clinical pattern is suggestive of female pattern alopecia, but a lack of follicular pores indicative of scarring is present. It can progress for years before slowly burning out. The etiology is unknown but genetic factors may be important. It is often associated with a history of traumatic hairstyling involving heat, traction, and chemicals. However, most patients of African descent without this disorder have similar styling habits. Nonetheless, avoidance of physical and chemical trauma to the scalp hair, the use of suitable shampoos and conditioners, and the encouragement of natural hairstyles may be helpful. Any infection should be treated. Topical or intralesional corticosteroids and systemic antibiotics may be useful and topical minoxidil should be tried with the hope of preventing further scarring and encouraging regrowth of recovering follicles. Current research into the etiology of this disorder will help to foster much-needed clinical trials of therapeutic agents.

  20. Central Sumatra enjoys success

    Energy Technology Data Exchange (ETDEWEB)

    Wongsosantiko, A.

    1977-05-02

    The Sihapas group contains the most prolific oil producing zones in the Central Sumatra Basin. It represents the transgressive, coarse clastic sequence deposited during the early Miocene. Some of these sandstone grade laterally into siltstones and shales of the Telisa Formation, believed to be a major source of rock for Central Sumatra oil. Recent exploratory wells drilled between the mountain front and coastal plain areas have provided more data for stratigraphic studies. These have resulted in subdivision of the lower Miocene transgressive sequence into discrete rock-stratigraphic units. The former Sihapas Formation has subsequently been elevated to group rank and now consists of several formations with the Duri Formation as the uppermost sand unit. This study covers Caltex's areas of operation, which includes the area between the Kampar River of the south, the Barumum River to the north, the Malacca Straits to the east, and the Barisan Mt. to the west. A basic map shows the regional scene, while a stratigraphic chart shows the lithology.

  1. en los pivotes centrales

    Directory of Open Access Journals (Sweden)

    Reynaldo Roque Rodés

    2005-01-01

    Full Text Available Se hace una revisión y comentarios sobre las ventajas y limitantes del empleo del LEPA (Low Enery Precision Aplication en los sistemas de riego de pivotes centrales. Estos sistemas o filosofía de manejo del agua para condiciones de escasez o mala calidad del líquido es una alternativa viable para la producción de alimentos. Introducida en la década del 80 en las planicies del sur de Texas, donde la alta evaporación del agua y la necesidad de regar grandes áreas con pivotes centrales obligaba a la búsqueda de una alternativa para incrementar al máximo la eficiencia de aplicación del riego. Aún en fase de estudio e introducción en Cuba para áreas específicas, puede ser una solución de incremento de los rendimientos de los cultivos, empleando menos agua y aguas con calidad limitada

  2. Laparoscopic assisted central pancreatectomy with pancreaticogastrostomy reconstruction - An alternative surgical technique for central pancreatic mass resection

    Directory of Open Access Journals (Sweden)

    Iswanto Sucandy

    2010-09-01

    Full Text Available Context: Central pancreatectomy has gained popularity in the past decade as treatment of choice for low malignant potential tumor in the midpancreas due to its ability to achieve optimal preservation of pancreatic parenchyma. Simultaneously, advancement in minimally invasive approach has contributed to numerous novel surgical techniques with significantly lower morbidity and mortality. With the purpose of improving patient outcomes, we describe a laparoscopic assisted central pancreatectomy with pancreaticogastrostomy as an alternative method to the previously described open central pancreatectomy with roux-en-y pancreaticojejunostomy reconstruction. Case Report: A 39 year old man presented to our clinic with a 2.5 cm neuroendocrine tumor at the neck of the pancreas. Laparoscopic assisted central pancreatectomy with pancreaticogastrostomy reconstruction was successfully performed. Operative time was 210 minutes with blood loss of 200 ml. Postoperative course was uneventful except for a minimal pancreatic leak which was controlled by an intraoperatively placed closed suction drain. At 2 week follow up, patient was asymptomatic with well preserved pancreatic endo and exocrine functions. Permanent pathology findings showed a well differentiated neuroendocrine tumor with negative margins and nodes. Conclusions: Laparoscopic assisted central pancreatectomy with pancreaticogastrostomy reconstruction is feasible and safe for a centrally located tumor. Laparoscopic assisted technique facilitates application of minimally invasive approach by increasing surgical feasibility in typically complex pancreatic operations.

  3. Laparoscopic assisted central pancreatectomy with pancreaticogastrostomy reconstruction - An alternative surgical technique for central pancreatic mass resection

    Directory of Open Access Journals (Sweden)

    Iswanto Sucandy

    2010-01-01

    Full Text Available Context: Central pancreatectomy has gained popularity in the past decade as treatment of choice for low malignant potential tumor in the midpancreas due to its ability to achieve optimal preservation of pancreatic parenchyma. Simultaneously, advancement in minimally invasive approach has contributed to numerous novel surgical techniques with significantly lower morbidity and mortality. With the purpose of improving patient outcomes, we describe a laparoscopic assisted central pancreatectomy with pancreaticogastrostomy as an alternative method to the previously described open central pancreatectomy with roux-en-y pancreaticojejunostomy reconstruction. Case Report: A 39 year old man presented to our clinic with a 2.5 cm neuroendocrine tumor at the neck of the pancreas. Laparoscopic assisted central pancreatectomy with pancreaticogastrostomy reconstruction was successfully performed. Operative time was 210 minutes with blood loss of 200 ml. Postoperative course was uneventful except for a minimal pancreatic leak which was controlled by an intraoperatively placed closed suction drain. At 2 week follow up, patient was asymptomatic with well preserved pancreatic endo and exocrine functions. Permanent pathology findings showed a well differentiated neuroendocrine tumor with negative margins and nodes. Conclusions: Laparoscopic assisted central pancreatectomy with pancreaticogastrostomy reconstruction is feasible and safe for a centrally located tumor. Laparoscopic assisted technique facilitates application of minimally invasive approach by increasing surgical feasibility in typically complex pancreatic operations.

  4. Centrality Measures in Urban Networks

    CERN Document Server

    Crucitti, P; Porta, S; Crucitti, Paolo; Latora, Vito; Porta, Sergio

    2005-01-01

    Centrality has revealed crucial for understanding the structural order of complex relational networks. Centrality is also relevant for various spatial factors affecting human life and behaviors in cities. We present a comprehensive study of centrality distributions over geographic networks of urban streets. Four different measures of centrality, namely closeness, betweenness, straightness and information, are compared over eighteen 1-square-mile samples of different world cities. Samples are represented by primal geographic graphs, i.e. valued graphs defined by metric rather than topologic distance where intersections are turned into nodes and streets into edges. The spatial behavior of centrality indexes over the networks is investigated graphically by means of colour-coded maps. The results indicate that a spatial analysis, that we term Multiple Centrality Assessment(MCA), grounded not a single but on a set of different centrality indices, allows an extended comprehension of the city structure, nicely captu...

  5. Orden monetario y bancos centrales Monetary order and Central Banks

    Directory of Open Access Journals (Sweden)

    Aglietta Michel

    1996-06-01

    Full Text Available Con el enfoque evolucionista e institucionalista de la economía de las convenciones francesa, este trabajo analiza el surgimiento histórico de la banca central y la creación institucional del 'arte de la banca central'. El artículo estudia los modelos formales del orden monetario, la banca libre y la banca central, y analiza los eventos históricos que llevaron a que el Banco de Inglaterra inventara el arte de manejar los bancos centrales en conjunción con el aprendizaje colectivo e institucional que lo hizo posible. Aglietta muestra que la banca central no es una creación del Estado sino una creación institucional endógena al sistema de mercado.With the evolutionist and institutionalist focus of the economics of the French conventions, this paper analyzes the historical rise of the central bank and the institutional creation of the 'art of the central bank'. The article studies formal models of the monetary order, free banking and the central bank, and analyzes the historie events that led to the Bank of England inventing the art of managing the central banks, in conjunction with the collective and institutional learning that made it possible. Aglietta shows that the central bank is not a creation of the State, but rather aninstitutional creation endogenous to the market system.

  6. New model of angular momentum transfer from the rotating central body of a two-body system into the orbital motion of this system (with application to the earth-moon system)

    CERN Document Server

    Schmutzer, E

    2005-01-01

    In a previous paper we treated within the framework of our Projective Unified Field Theory (Schmutzer 2004, Schmutzer 2005a) the 2-body system (e.g. earth-moon system) with a rotating central body in a rather abstract manner. Here a concrete model of the transfer of angular momentum from the rotating central body to the orbital motion of the whole 2-body system is presented, where particularly the transfer is caused by the inhomogeneous gravitational force of the moon acting on the oceanic waters of the earth, being modeled by a spherical shell around the solid earth. The theory is numerically tested. Key words: transfer of angular momentum from earth to moon, action of the gravitational force of the moon on the waters of the earth.

  7. Observation and Nursing Care Central Venous Catheter in the Clinical Application%中心静脉置管在临床应用中的观察与护理

    Institute of Scientific and Technical Information of China (English)

    石英

    2014-01-01

    目的:总结中心静脉置管的临床护理方法。方法中心静脉置管前加强与患者的沟通,争取患者的理解和配合;中心静脉置管中注意并发症的观察和处理;中心静脉置管后加强导管的护理,预防穿刺点和导管感染,预防导管内血栓形成和栓塞。结果254例中心静脉置管保留时间20~180d,平均69d;无1例出现穿刺处感染和导管内感染,拔除留置针做细菌培养,无1例细菌培养阳性;无1例导管脱出;无1例导管拔除。结论加强中心静脉置管术前、术中和术后护理,对并发症的预防具有重要意义。%Objective to summarize the clinical nursing methods of the central venous catheter. Methods to strengthen the communication with patients of the center venipuncture,strive for the patients understanding and cooperation;Central venous catheter in pay at ention to the observation of complications and treatment. Results 254 cases of central venous catheter retention time of 20~180d,an average of 69d; No 1 case of catheter removal. Conclusion to strengthen the central venous catheter preoperative,intraoperative and postoperative nursing, is of great significance to the prevention of complications.

  8. UA1 central detector

    CERN Multimedia

    The UA1 central detector was crucial to understanding the complex topology of proton-antiproton events. It played a most important role in identifying a handful of Ws and Zs among billions of collisions. The detector was a 6-chamber cylindrical assembly 5.8 m long and 2.3 m in diameter, the largest imaging drift chamber of its day. It recorded the tracks of charged particles curving in a 0.7 Tesla magnetic field, measuring their momentum, the sign of their electric charge and their rate of energy loss (dE/dx). Atoms in the argon-ethane gas mixture filling the chambers were ionised by the passage of charged particles. The electrons which were released drifted along an electric field shaped by field wires and were collected on sense wires. The geometrical arrangement of the 17000 field wires and 6125 sense wires allowed a spectacular 3-D interactive display of reconstructed physics events to be produced.

  9. UA2 central calorimeter

    CERN Multimedia

    The UA2 central calorimeter measured the energy of individual particles created in proton-antiproton collisions. Accurate calibration allowed the W and Z masses to be measured with a precision of about 1%. The calorimeter had 24 slices like this one, each weighing 4 tons. The slices were arranged like orange segments around the collision point. Incoming particles produced showers of secondary particles in the layers of heavy material. These showers passed through the layers of plastic scintillator, generating light which was taken by light guides (green) to the data collection electronics. The amount of light was proportional to the energy of the original particle. The inner 23 cm of lead and plastic sandwiches measured electrons and photons; the outer 80 cm of iron and plastic sandwiches measured strongly interacting hadrons. The detector was calibrated by injecting light through optical fibres or by placing a radioactive source in the tube on the bottom edge.

  10. UPVAPOR: computer application for the analysis of the results of Cofrentes Nuclear Power Plant production; UPVAPOR: Aplicacion informatica para el analisis de resultados de produccion en Central Nuclear Cofrentes

    Energy Technology Data Exchange (ETDEWEB)

    Palomo, M. J.; Baraza Peregrin, A.; Bucho Piqueras, L.; Vaquer Perez, J. I.; Lopez Lopez, B.

    2010-07-01

    UPVapor is a software developed for the Cofrentes Nuclear Power Plant Group of Results. This application presents a graphical environment for analysis in which the user has available many variables registered to configure the graphics. This application saves a lot of time at work because it allows other users to do their own analysis without resorting to analysts.

  11. Betweenness Centrality in Graphs

    OpenAIRE

    2014-01-01

    The first book devoted exclusively to quantitative graph theory, Quantitative Graph Theory: Mathematical Foundations and Applications presents and demonstrates existing and novel methods for analyzing graphs quantitatively. Incorporating interdisciplinary knowledge from graph theory, information theory, measurement theory, and statistical techniques, this book covers a wide range of quantitative-graph theoretical concepts and methods, including those pertaining to real and random graphs such ...

  12. Central heating: package boilers

    Energy Technology Data Exchange (ETDEWEB)

    Farahan, E.

    1977-05-01

    Performance and cost data for electrical and fossil-fired package boilers currently available from manufacturers are provided. Performance characteristics investigated include: unit efficiency, rated capacity, and average expected lifetime of units. Costs are tabulated for equipment and installation of various package boilers. The information supplied in this report will simplify the process of selecting package boilers required for industrial, commercial, and residential applications.

  13. Betweenness centrality patterns in random planar graphs

    CERN Document Server

    Lion, Benjamin

    2016-01-01

    Random planar graphs appear in a variety of context and it is important for many different applications to be able to characterize their structure. Local quantities fail to give interesting information and it seems that path-related measures are able to convey relevant information about the organization of these structures. In particular, nodes with a large betweenness centrality (BC) display non-trivial patterns, such as loops of very central nodes. We discuss briefly empirical results for different random planar graphs and we propose a toy model which allows us to discuss the condition for the emergence of non-trivial patterns such as central loops. This toy model is made of a star network with $N_b$ branches of size $n$ and links of weight $1$, superimposed to a loop at distance $\\ell$ from the center and with links of weight $w$. We estimate for this model the BC at the center and on the loop and we show that the loop can be more central than the origin if $w

  14. The application of root cause analytical method in reducing infections related to central venous catheter%根因分析法在降低中心静脉导管相关性感染中的应用

    Institute of Scientific and Technical Information of China (English)

    江寅芳; 郭海珍; 夏娟; 夏肖枫; 冯惠春

    2015-01-01

    OBJECTIVE To reduce the incidence of central venous catheter‐related infections and improve the safety of the patients with central venous catheter by root cause analytical method .METHODS The clinical data of 768 cases and 838 cases treated with central venous catheter in 2012 and 2013 were investigated .Through using the method of root cause analysis to analyze proximal causes and root causes for the 84 cases of catheter‐related infections in 2012 ,the central venous catheter assessment and monitoring mechanism were set to improve the catheter insertion method and the maintenance method ,and strengthen the training of nurses and the mission to patients and their families .The effect was traced in 2013 .RESULTS There were 84 cases with central venous catheter‐related infections in 2012 ;the infection rate was 10 .9% .And in 2013 ,this number was 46 cases;the infection rate was 5 .5% .The differences of the two years′infection rate was significant(P<0 .05) .The insertion site infection and catheter‐related infection (CRBSI) incidence of 2013 were 29(3 .5% )and 17(2 .0% ) ,lower than those of 2012 ,60(7 .8% )and 24(3 .1% ) ,there was significant differences (P<0 .05) .According to the days of the central catheter indwelling statistics ,the daily infection rate fell from 7 .2/1000 to 3 .5/1000 .CONCLUSION Root cause analytical method can provide a scientific way for systematically and effectively reducing the occurrence of central venous catheter‐related infections .%目的:通过根因分析减少中心静脉置管后相关性感染的发生率,提高置管患者的安全性。方法调查2012、2013年行中心静脉置管各768、838例患者资料,对2012年发生中心静脉导管感染患者,运用根因分析方法进行近端原因、根本原因分析,制定中心静脉导管的评估和监控机制,改进导管的置管与维护方法,强化对护士的培训和对患者及家属的宣教,于2013年对改

  15. HIS Central and the Hydrologic Metadata Catalog

    Science.gov (United States)

    Whitenack, T.; Zaslavsky, I.; Valentine, D. W.

    2008-12-01

    The CUAHSI Hydrologic Information System project maintains a comprehensive workflow for publishing hydrologic observations data and registering them to the common Hydrologic Metadata Catalog. Once the data are loaded into a database instance conformant with the CUAHSI HIS Observations Data Model (ODM), the user configures ODM web service template to point to the new database. After this, the hydrologic data become available via the standard CUAHSI HIS web service interface, that includes both data discovery (GetSites, GetVariables, GetSiteInfo, GetVariableInfo) and data retrieval (GetValues) methods. The observations data then can be further exposed via the global semantics-based search engine called Hydroseek. To register the published observations networks to the global search engine, users can now use the HIS Central application (new in HIS 1.1). With this online application, the WaterML-compliant web services can be submitted to the online catalog of data services, along with network metadata and a desired network symbology. Registering services to the HIS Central application triggers a harvester which uses the services to retrieve additional network metadata from the underlying ODM (information about stations, variables, and periods of record). The next step in HIS Central application is mapping variable names from the newly registered network, to the terms used in the global search ontology. Once these steps are completed, the new observations network is added to the map and becomes available for searching and querying. The number of observations network registered to the Hydrologic Metadata Catalog at SDSC is constantly growing. At the time of submission, the catalog contains 51 registered networks, with estimated 1.7 million stations.

  16. 疾病控制论在中枢神经损伤研究中的应用探讨%Discussion about the Application of Disease Cybernetics in the Research of Central Nervous System Injure

    Institute of Scientific and Technical Information of China (English)

    陆志方; 敖强

    2015-01-01

    To discuss and present a new thinking about the research of central nervous system injure based on disease cybernetics and the perfect health service system .There are three stages of the whole process of central nervous system injury ,including prevention ,treatment ,rehabilitation .This article is to analyze the neuroscience research process about research target ,relates to the field ,the focus of cooperation of every stage ,and put forward improvement strategy .The new neuroscience research strategies include:unified goal ,systemic ,horizontal linkages .The strategy based on disease cybernetics may contribute to reduce the incidence and disability of central nervous system injure .%根据疾病控制论的原理和完美医疗目标体系,探讨提出一种针对中枢神经损伤的神经科学研究新思路。编制中枢神经损伤的全流程,包括预防、救治、康复3个阶段,对每个阶段中神经科学的研究目标、涉及领域、合作重点进行分析,提出改进策略。新的神经科学研究策略包括:统一目标、系统性、横向联系。基于疾病控制论提出的新策略,可能有利于降低中枢神经损伤的发生率和致残率。

  17. Central Place Theory and Distribution of Post Offices in Cities

    Institute of Scientific and Technical Information of China (English)

    2000-01-01

    The feasibility of application of the Central Place Theory in the distribution of post offices in cities is analysed, the grade scale structure and space distribution structure Shijiazhauang of post offices in city are studied, the research results prove the actual value of the Central Place Theory, and the suggestion of adjustment in the space distribution Shijiazhuang of post offices in city is put forward.

  18. Application des analyses minéralogiques et géotechniques des Argiles dans l’étude des glissements de terrains: exemples du Prérif central (Maroc septentrional

    Directory of Open Access Journals (Sweden)

    Faleh Ali

    2002-01-01

    Full Text Available En el Prerif central resulta muy común el paisaje de vertientes afectadas por deslizamientos de terrenos, recientes o reactivados. Los factores responsables de esta morfodinámica acelerada están ligados al predominio de rocas blandas, a las precipitaciones intensas e irregulares y a las fuertes pendientes. El objetivo principal de este trabajo es determinar la susceptibilidad de las diferentes facies a los movimientos en masa, en relación con las características mineralógicas y geotécnicas de las arcillas.

  19. 锥形束CT在上颌埋伏中切牙诊断中的应用%Application of cone beam computed tomography in the diagnosis of unerupted maxillary central incisor

    Institute of Scientific and Technical Information of China (English)

    顾月光; 王珊; 谷妍; 赵春洋; 许远; 刘可; 王林

    2012-01-01

    目的:探讨锥形束CT(CBCT)在上颌埋伏中切牙诊断中的作用.方法:选择正畸临床33例上颌中切牙埋伏阻生患者作为研究对象,拍摄全景片和CBCT,由10位正畸医生对33例埋伏牙患者的全景片和CBCT分别进行测量、分析,填写研究表格.所得数据用SPSS 17.0软件,采用McNemar检验、Kappa检验和配对t检验进行统计学分析.结果:CBCT与全景片对埋伏牙是否弯根、近中切角距中线距离和有无多生牙等分析项目没有统计学差异,其余分析项目均有统计学差异.结论:对上颌埋伏中切牙诊断,CBCT更直观、三维测量更精确,更好地指导临床.%Objective: To study the effect of cone beam computed tomography (CBCT) in the diagnosis of unerupted maxillary central incisor. Methods: 33 patients undergoing orthodontic treatment were included. For each unerupted maxillary central incisor, panoramic radiograph( PR) and CBCT were used in diagnosis. Ten orthodontic dentists completed the table which had been formulated. The images were measured and the data analysis was performed using McNemar test, Kappa test and paired t-test by SPSS 17. 0 soft ware. Results: The dimension data of the central incisor, the distance between the mesial incisor angle and the midline of the arch, dilacera-tion of the central incisor root and the existence supernumerary teeth obtained by PR and CBCT showed no statistic difference, while the other analysis items did. Conclusion: CBCT diagnosis of the unerupted incisor is more direct and more accuracy than panoramic radiograph.

  20. Application of ultrasonic combined with Back-propagation neural network in the diagnosis of central precocious puberty%超声结合 BP 神经网络技术诊断女童中枢性性早熟

    Institute of Scientific and Technical Information of China (English)

    梁哲浩; 鲁伟

    2015-01-01

    目的:探讨超声结合人工神经网络技术在女童中枢性性早熟诊断中的应用价值。方法选用170例性早熟女童进行常规超声检查子宫、卵巢,以其中130例的子宫体积、卵巢体积以及双侧卵巢最大卵泡内径为输入变量,以中枢性性早熟或非中枢性性早熟为输出变量,建立反向传播(BP)神经网络,并对另40例性早熟病例分类。结果利用 BP 神经网络结合常规超声检查对中枢性性早熟诊断的敏感性、特异性和准确率分别为95.0%、85.0%、90.0%。结论神经网络结合超声检查对中枢性性早熟的诊断和鉴别诊断具有较大的价值。%Objective To explore the value of ultrasonic combined with Back‐propagation artificial neural network in the diagnosis of central precocious puberty .Methods In 170 girls with precocious puberty ,the uterine and ovarian were ex‐amined with ultrasound ,in which 130 cases of uterine volume ,ovarian volume and bilateral ovarian follicles biggest diame‐ter were taken as inputs ,the central precocious puberty or non‐central precocious puberty as output variable .The back‐propagation (BP) neural network was established using such data .The other 40 cases were sorted by this BP neural net‐work .Results The diagnostic sensitivity ,specificity and accuracy of the BP neural network combination of ultrasound were 95 .0% ,85 .0% and 90 .0% ,respectively .Conclusion The BP neural network in combination of ultrasound is help‐ful in diagnosing central precocious puberty .

  1. Application of central venous catheter in continuing drainage of cerebrospinal fluid from Lumbar cerebellomedllary cistern%中心静脉导管在持续腰大池脑脊液引流术中的应用

    Institute of Scientific and Technical Information of China (English)

    胡建锋; 许小兵; 苏杭; 骆实

    2009-01-01

    Objective To observe the effect of central venous catheter in continuing drainage of cerebrospinal fluid(CSF) from lumbar cerehellomedullary cistern.Methods 86 cases with subarachnoid hemorrhage(SAH) were randomly divided into two groups,43 cases in each group.Epidural catheter and central venous catheter were used in two groups respectively,complications during and after operative were recorded.Results Ievement ratio of placing catheter in both groups was high,nerve irritation of lower limbs and perineal region appeared during placing tuheo there was no difference in between the two groups (P>0.05).Compared with epidural catheter group,adverse,effect such as inadequate drainage,catheter defluvium,infection and leakage of CSF in central venous catheter group decreased markedly (P<0.05 or P<0.01).Conclusions Entral venous catheter can drain CSF smoothly,control flow rate of CSF easily.Central venous catheter can .satisfy continue drainage,of CSF in lumbar cerehellomedullary cistern.%目的 观察中心静脉导管在持续腰大池脑脊液引流术中的应用效果.方法 将86例蛛网膜下腔出血病人被随机分为2组,分别采用硬膜外导管及中心静脉导管进行持续腰大池引流,比较置管术中和术后并发症的发生情况.结果 两种导管一次性置管成功率均较高,但在置管过程中均易出现下肢及会阴部异感不适等神经刺激症状,组间比较无显著性差异(P>0.05);与硬膜外导管组相比,中心静脉导管组出现引流不畅、导管脱落、感染及脑脊液漏等不良反应明显降低(P<0.05或P<0.01).结论 中心静脉管能保证引流通畅,容易控制流速和流量,适合持续腰大池引流术的需要.

  2. 中心静脉导管接负压吸引器在结核性胸腔积液中的应用%Application of central venous catheter connected with the negative pressure aspirator in tuberculous pleural effusion

    Institute of Scientific and Technical Information of China (English)

    王赞

    2014-01-01

    目的:探讨中心静脉导管接负压吸引器在结核性胸腔积液治疗中的疗效。方法:收治结核性胸膜炎患者100例,随机分为两组,治疗组50例,采用中心静脉导管接负压吸引器持续引流胸腔积液;对照组50例,采用常规中心静脉导管接无菌引流袋引流胸腔积液。两组均用2HRZE/10HRE标准抗痨方案治疗,观察胸腔积液引流通畅,胸腔积液消失时间。结果:治疗组胸腔积液吸收时间短,不易造成引流管阻塞。结论:中心静脉导管接负压吸引器引流治疗结核性胸腔积液疗效确切。%Objective:To explore the curative effect of central venous catheter connected with the negative pressure aspirator in tuberculous pleural effusion.Methods:100 patients with tuberculous pleurisy were selected,they were randomly divided into the treatment group and the control group with 50 cases in each.The treatment group was given drainage of the pleural effusion by central venous catheter connected with the negative pressure aspirator.The control group was given drainage of the pleural effusion by the central venous catheter with a sterile drainage bag.The two groups were treated with the standard of 2HRZE/10HRE tuberculosis scheme.Pleural effusion drainage and the hydrothorax disappearance time were observed.Results:In the treatment group,hydrothorax absorption time was short,and it was not easy to cause obstruction of drainage tube.Conclusion:The curative effect of central venous catheter connected with the negative pressure aspirator in tuberculous pleural effusion is obviously.

  3. Application of central composite design and rank annihilation factor analysis for optimization of mixed chelate of UO{sub 2}{sup 2+} complex with ammonium-N,N-tetramethylenedithiocarbamate and estimation of K{sub f} value

    Energy Technology Data Exchange (ETDEWEB)

    Aslani, Mahmut A.A.; Kuru, Yesim F.; Aslani, Ceren Kutahyali [Ege Univ., Izmir (Turkey). Inst. of Nuclear Sciences

    2016-04-01

    The interaction between UO{sub 2}{sup 2+} and ammonium-N,N-tetramethylenedithiocarbamate (ATMDTC) was investigated experimentally by means of UV-Vis spectrophotometry. Central Composite Design (CCD) was applied to optimisation of reaction with 54 runs in duplicate. This design type was also used to developed mathematical model equation. Analysis of Variance (ANOVA) indicates that the terms of the model are significant within the 95% confident interval. Remarkably initial solution pH, initial ATMDTC concentration, initial Cu{sup 2+} concentration and temperature have effect on the reaction. Formation constant (log K{sub f}) was calculated as 2.917 by using Rank Annihilation Factor Analysis (RAFA).

  4. Application of Centralized Training Combined with Complementary Companion Study in Training of Stoma Visitor%集中培训联合结伴式互补学习在造口探访员培训中的应用

    Institute of Scientific and Technical Information of China (English)

    蔡一波; 陈秀云; 谢玲女

    2015-01-01

    Objective To evaluate the feasibility and effects of centralized training combined with complementary companion study in stoma visitor training. Methods Six selected stoma visitors received intensive training on theoretical knowledge of stoma visit, then they obtained practical visiting skills in a complementary learning way. Comprehensive evaluation of stoma visitor`s knowledge, visitors’ self-assessment of problem-solving ability and self-care ability of the patients to whom visitors paid a visit after the centralized training. Results The knowledge of six selected stoma visitors was improved after the centralized training. In the process of complementary companion study, problem-solving ability was significantly improved in visitor ’s self-assessment. Self-care ability of the patients was significantly promoted when compared with those without visits. Conclusion Centralized training combined with complementary companion study is practical for the stoma visitor training ,which is of significance and worth to be promoted.%目的:评估集中培训联合结伴式互补学习培训造口探访员的可行性及效果。方法首先招募选拔6名造口探访员,对造口探访相关理论知识进行集中授课培训,而对探访实践技能采用结伴式互补学习的多元化培训方式进行培训,培训结束后,从对探访员知识掌握程度评价、独立解决问题能力的自我评价、被探访者探访后自我护理能力提高效果3个方面进行综合评价。结果6名探访者集中培训后的知识测评分显著高于培训前,在结伴式互补学习过程中,培训6月时探访员自我测评独立解决问题比例显著提高,接受探访患者的自我护理能力显著高于同期未接受探访者。结论集中培训联合结伴式互补学习的培训方法适用对造口探访员的培训,具有推广价值。

  5. Centralizers in simple locally finite groups

    Directory of Open Access Journals (Sweden)

    Mahmut Kuzucuoğlu

    2013-03-01

    Full Text Available This is a survey article on centralizers of finitesubgroups in locally finite, simple groups or LFS-groups as wewill call them. We mention some of the open problems aboutcentralizers of subgroups in LFS-groups and applications of theknown information about the centralizers of subgroups to thestructure of the locally finite group. We also prove thefollowing: Let $G$ be a countably infinite non-linear LFS-groupwith a Kegel sequence $mathcal{K}={(G_i,N_i | iinmathbf{N} }$. If there exists an upper bound for ${ |N_i| |iin mathbf{N} }$, then for any finite semisimplesubgroup $F$ in $G$ the subgroup $C_G(F$ has elements oforder $p_i$ for infinitely many distinct prime $p_i$. Inparticular $C_G(F$ is an infinite group. This answers Hartley'squestion provided that there exists a bound on ${ |N_i| | iin mathbf{N}$.

  6. Central Disorders of Hypersomnolence

    Science.gov (United States)

    Khan, Zeeshan

    2015-01-01

    The central disorders of hypersomnolence are characterized by severe daytime sleepiness, which is present despite normal quality and timing of nocturnal sleep. Recent reclassification distinguishes three main subtypes: narcolepsy type 1, narcolepsy type 2, and idiopathic hypersomnia (IH), which are the focus of this review. Narcolepsy type 1 results from loss of hypothalamic hypocretin neurons, while the pathophysiology underlying narcolepsy type 2 and IH remains to be fully elucidated. Treatment of all three disorders focuses on the management of sleepiness, with additional treatment of cataplexy in those patients with narcolepsy type 1. Sleepiness can be treated with modafinil/armodafinil or sympathomimetic CNS stimulants, which have been shown to be beneficial in randomized controlled trials of narcolepsy and, quite recently, IH. In those patients with narcolepsy type 1, sodium oxybate is effective for the treatment of both sleepiness and cataplexy. Despite these treatments, there remains a subset of hypersomnolent patients with persistent sleepiness, in whom alternate therapies are needed. Emerging treatments for sleepiness include histamine H3 antagonists (eg, pitolisant) and possibly negative allosteric modulators of the gamma-aminobutyric acid-A receptor (eg, clarithromycin and flumazenil). PMID:26149554

  7. [MANAGEMENT OF CENTRAL HYPERSOMNIAS].

    Science.gov (United States)

    Dauvilliers, Yves; Lopez, Régis

    2016-06-01

    Central hypersomnias include narcolepsy type 1, type 2 and idiopathic hypersomnia with daytime sleepiness excessive in the foreground of the clinical symptoms. Despite major advances in our understanding of the mechanisms of the narcolepsy type 1 with a low level of hypocretin-1 in cerebrospinal fluid, its current management is only symptomatic. The current management is also only symptomatic for type 2 narcolepsy and idiopathic hypersomnia with an unknown pathophysiology. Treatment options may vary from a single drug targeting several symptoms or several drugs treating a specific symptom. The treatment of daytime sleepiness is based on modafinil in first intention. Other psychostimulants such as methylphenidate, pitolisant and exceptionally dextro-amfetamine may be considered. In narcolepsy type 1, antidepressants such as inhibitors of the reuptake of serotonin and noradrenaline will be considered to improve cataplexy. Sodium oxybate is an effective treatment on sleepiness, cataplexy and bad night sleep in narcolepsy. The management for other symptoms or comorbidities should be considered it necessary such as hallucinations, sleep paralysis, the disturbed nighttime sleep, unpleasant dreams, parasomnias, depressive symptoms, overweight/obesity, cardiovascular disease and obstructive sleep apnea syndrome. Important therapeutic perspectives are to be expected concerning new psychostimulant and anticataplectiques, but mainly on immune-based therapies administered as early as possible after disease onset and on hypocretin replacement therapy for patients with severe symptoms.

  8. 外周中心静脉导管与中心静脉导管在肠外营养应用中的比较%Comparison on application of peripherally inserted central venous catheter and central venous catheter for patients undergoing parenteral nutrition

    Institute of Scientific and Technical Information of China (English)

    柴惠红; 朱明丽; 范永琴

    2007-01-01

    @@ 肠外营养(parenteral nutrition,PN)是危重症病人重要的营养支持手段之一,由于肠外营养往往输液量大、液体渗透压高、对外周静脉刺激大,所以需要经中心静脉导管(central venous catheters,CVC)输注.常规的中心静脉导管一般有颈内静脉、锁骨下静脉和股静脉导管,但在穿刺置管和输液过程中都有可能发生不同程度的并发症.

  9. Centrality Fingerprints for Power Grid Network Growth Models

    CERN Document Server

    Gurfinkel, Aleks Jacob; Rikvold, Per Arne

    2015-01-01

    In our previous work, we have shown that many of the properties of the Florida power grid are reproduced by deterministic network growth models based on the minimization of energy dissipation $E_\\mathrm{diss}$. As there is no $a~ priori$ best $E_\\mathrm{diss}$ minimizing growth model, we here present a tool, called the "centrality fingerprint," for probing the behavior of different growth models. The centrality fingerprints are comparisons of the current flow into/out of the network with the values of various centrality measures calculated at every step of the growth process. Finally, we discuss applications to the Maryland power grid.

  10. Development and Application of Self-lubricating and Self-spinning Sucker Rod Centralizer%自润滑自旋转型抽油杆扶正器研制与应用

    Institute of Scientific and Technical Information of China (English)

    郑学成; 马志全

    2011-01-01

    针对大庆油田螺杆泵现有扶正器存在的摩擦阻力大、寿命短等问题,研制了能够自润滑、自旋转的新型抽油杆扶正器,包括与抽油杆连接的接箍式和安装于杆体上的杆轴式2种结构.特点是利用扶正环内部轴承固体润滑方式来减小扶正摩擦阻力,外部耐磨扶正环相对于油管运动少而降低磨损和磨阻,能够在保证扶正效果的同时降低摩擦阻力,延长系统寿命.%On the basis of analysis of the current centralizer's friction and rod dropped problems in Daqing oilfield,a new-type of centralizers was developed which can be self-lubricating and selfspinning. Two kinds of construction are introduced: coupling connection and thermal setting rod connection that stabilizer has an inner solid lubricating bearing and outer resistance synthetic nylon. It can reduce rod eccentric friction and wear and increase the system life.

  11. 中心静脉穿刺导管在癌性胸腔积液中的应用%Application of central venous catheter in Cancerous Pleural Effusion

    Institute of Scientific and Technical Information of China (English)

    曾少云; 陈志军

    2014-01-01

    目的:解决癌性胸腔积液反复穿刺的缺点。方法:收治癌性胸腔积液患者17例,应用中心静脉穿刺导管做胸腔留置引流术。结论:中心静脉穿刺导管引流较传统反复穿刺引流具有很多优点。本方法引流效果明显优于传统引流方法及反复穿刺的方法。%Objective:To solve the disadvantage of malignant pleural effusion repeated puncture.Methods:17 patients with malignant pleural effusion were selected,We did indwelling pleural drainage by central venous catheter.Experience:The central venous catheter has more advantages than the traditional repeated puncture drainage.Conclusion:This method is better than the traditional drainage drainage method and repeated puncture.

  12. y Banca Central

    Directory of Open Access Journals (Sweden)

    Ángel García Banchs

    2008-01-01

    Full Text Available Las teorías monetarias modernas, ortodoxas y heterodoxas, han pasado por alto el hecho de que posterior a la Segunda Guerra Mundial el mundo quedó dividido entre economías emisoras y receptoras de reservas, pasando el sistema monetario internacional desde entonces a ser completamente asimétrico. De allí que, desde el punto de vista teórico, señalemos la necesidad de tomar en cuenta si las economías emiten o no una moneda de reserva internacional, pues ello explicaría la existencia de diversas prácticas monetarias a nivel mundial. Este trabajo propone, y calcula, indicadores basados en datos provenientes de los balances de activos y pasivos de quince bancos centrales pertenecientes a Norteamérica, Suramérica, Europa y Asia. Los hallazgos con respecto a las diversas estructuras de activos y pasivos confirman la hipótesis acerca de la presencia de tales asimetrías. Se infiere en consecuencia que la política monetaria es menos flexible pero más influyente en las economías receptoras de reservas, y a la vez más flexible pero menos influyente en las economías emisoras. En pocas palabras, la exogeneidad de la tasa de interés de corto plazo es más débil en el caso de las economías receptoras de reservas las cuales se ven obligadas a acumular divisas y a procurar la estabilidad del tipo de cambio, debido a que sus monedas locales no son aceptadas en el exterior. Así, aunque la oferta crediticia es endógena en esas economías, las mismas no han sido capaces de librarse aún de la necesidad de mantener reservas monetarias en divisas extranjeras

  13. Dublin South Central (DSC)

    LENUS (Irish Health Repository)

    O'Gorman, Clodagh S M

    2010-12-01

    Children who appear healthy, even if they have one or more recognized cardiovascular risk factors, do not generally have outcomes of cardiovascular or other vascular disease during childhood. Historically, pediatric medicine has not aggressively screened for or treated cardiovascular risk factors in otherwise healthy children. However, studies such as the P-Day Study (Pathobiological Determinants of Atherosclerosis in Youth), and the Bogalusa Heart Study, indicate that healthy children at remarkably young ages can have evidence of significant atherosclerosis. With the increasing prevalence of pediatric obesity, can we expect more health problems related to the consequences of pediatric dyslipidemia, hypertriglyceridemia, and atherosclerosis in the future? For many years, medications have been available and used in adult populations to treat dyslipidemia. In recent years, reports of short-term safety of some of these medications in children have been published. However, none of these studies have detailed long-term follow-up, and therefore none have described potential late side-effects of early cholesterol-lowering therapy, or potential benefits in terms of reduction of or delay in cardiovascular or other vascular end-points. In 2007, the American Heart Association published a scientific statement on the use of cholesterol-lowering therapy in pediatric patients. In this review paper, we discuss some of the current literature on cholesterol-lowering therapy in children, including the statins that are currently available for use in children, and some of the cautions with using these and other cholesterol-lowering medications. A central tenet of this review is that medications are not a substitute for dietary and lifestyle interventions, and that even in children on cholesterol-lowering medications, physicians should take every opportunity to encourage children and their parents to make healthy diet and lifestyle choices.

  14. Central African Republic.

    Science.gov (United States)

    1989-11-01

    The Central African Republic contains 242,000 square miles, which rolling terrain almost 2000 feet above sea level. The climate is tropical, and it has a population of 2.8 million people with a 2.5% growth rate. There are more than 80 ethnic groups including Baya 34%, Banda 28%, Sara 10%, Mandja 9%, Mboum 9%, and M'Baka 7%. The religions are traditional African 35%, protestant 25%, Roman Catholic 25%, and Muslim 15%, and the languages are French and Sangho. The infant mortality rate is 143/1000, with expectancy at 49 years and a 40% literacy rate. The work force of 1 million is 70% agricultural, industry 6% and commerce and service 6% and government 3%. The government consists of a president assisted by cabinet ministers and a single party. Natural resources include diamonds, uranium, timber, gold, and oil, and major industries are beverages, textiles, and soap. Agricultural products feature coffee, cotton, peanuts, tobacco, food crops and livestock. Most of the population live in rural areas and most of the 80 ethnic groups have their own language. This is one of the world's least developed countries, with a per capita income of $375/year. The main problems with development are the poor transportation infrastructure, and the weak internal and international marketing systems. The US and various international organizations have aided in agriculture development, health programs, and family planning. US investment is mainly in diamond and gold mining, and although oil drilling has been successful it is not economically feasible at current prices.

  15. Central cooling: absorptive chillers

    Energy Technology Data Exchange (ETDEWEB)

    Christian, J.E.

    1977-08-01

    This technology evaluation covers commercially available single-effect, lithium-bromide absorption chillers ranging in nominal cooling capacities of 3 to 1,660 tons and double-effect lithium-bromide chillers from 385 to 1,060 tons. The nominal COP measured at operating conditions of 12 psig input steam for the single-effect machine, 85/sup 0/ entering condenser water, and 44/sup 0/F exiting chilled-water, ranges from 0.6 to 0.65. The nominal COP for the double-effect machine varies from 1.0 to 1.15 with 144 psig entering steam. Data are provided to estimate absorption-chiller performance at off-nominal operating conditions. The part-load performance curves along with cost estimating functions help the system design engineer select absorption equipment for a particular application based on life-cycle costs. Several suggestions are offered which may be useful for interfacing an absorption chiller with the remaining Integrated Community Energy System. The ammonia-water absorption chillers are not considered to be readily available technology for ICES application; therefore, performance and cost data on them are not included in this evaluation.

  16. Central Hypothyroidism in Miniature Schnauzers

    NARCIS (Netherlands)

    Voorbij, Annemarie M W Y; Leegwater, Peter A J; Buijtels, Jenny J C W M; Daminet, Sylvie; Kooistra, Hans S

    2016-01-01

    BACKGROUND: Primary hypothyroidism is a common endocrinopathy in dogs. In contrast, central hypothyroidism is rare in this species. OBJECTIVES: The objective of this article is to describe the occurrence and clinical presentation of central hypothyroidism in Miniature Schnauzers. Additionally, the p

  17. The Centralized Management and Clinical Application of Ventilators in Modern Hospital%现代医院呼吸机的集中管理与临床应用

    Institute of Scientific and Technical Information of China (English)

    何莺; 邢素美; 夏文俊

    2011-01-01

    目的 探讨现代医院呼吸机的集中管理模式及在临床中的推广应用.方法 观察、总结、分析近3年195例机械通气患者呼吸机集中管理的效果.结果 集中专人负责呼吸机的保管、供应、调试、保养、维护、消毒及故障排除,195例机械通气患者虽遇到各类报警950例,但由于发现及时、处理得当,均未对患者造成重大影响,呼吸机的完好率及使用率均达百分之百.结论 加强现代医院呼吸机的集中科学管理,培养造就一支高素质的专业人才队伍,将显著提高呼吸机的使用率和重症患者救治的成功率.%Objective To investigate the centralized management mode and clinical promotion of ventilators in modern hospitals.Methods 0bserved,9ummarized,and analyzed the centralized ventilators management effects of 195 patients with mechanical ventilation.Results Set persons specially designated for the jobs of storage, supply, debugging, maintenance, protection, disinfection and troubleshooting. 195 cases of patients with mechanical ventilation encountered 950 cases of various types of alarm,because of dealing with these problems timely and properly ,there was no significant loss on the patients, and the rate of the ventilators in good condition and urilization reached 100 percent.Conclsion By strengthening the centralized modern hospital ventilator scientific management,training and fostering a high quality team of professionals,we will significantly improve the utilization rate of the ventilator and the success rate rescue of critical patients.

  18. Central presbycusis: an emerging view.

    Science.gov (United States)

    Gates, George A

    2012-07-01

    Age-related dysfunction of the central auditory system (central presbycusis) is common but rarely looked for by those who provide aural rehabilitation. Patients who complain of difficulty hearing in noise--the key symptom of central presbycusis--are generally disadvantaged with conventional rehabilitation. This symptom should be documented with commercially available speech-in-noise tests, which use materials that are uncomplicated to administer. Those patients who perform poorly on such tests should have a customized rehabilitation program aimed at optimizing their remaining communication abilities. Otolaryngologists who provide auditory rehabilitation may wish to consider expanding their practices to meet the communication needs of older patients with central presbycusis. Central presbycusis is an emerging area for basic and clinical research in auditory neurotology, particularly in the relation of cognitive dysfunction to impaired auditory processing.

  19. Central Limit Theorem for Nonlinear Hawkes Processes

    CERN Document Server

    Zhu, Lingjiong

    2012-01-01

    Hawkes process is a self-exciting point process with clustering effect whose jump rate depends on its entire past history. It has wide applications in neuroscience, finance and many other fields. Linear Hawkes process has an immigration-birth representation and can be computed more or less explicitly. It has been extensively studied in the past and the limit theorems are well understood. On the contrary, nonlinear Hawkes process lacks the immigration-birth representation and is much harder to analyze. In this paper, we obtain a functional central limit theorem for nonlinear Hawkes process.

  20. 基于 GPS 和全站仪井筒十字中线恢复测量方法的研究%The Application of GPS and Total Station in Recovery of Shaft Cross Central Line

    Institute of Scientific and Technical Information of China (English)

    王志伟; 曲国庆; 袁兴明; 祁仰旭

    2014-01-01

    This article in view of the method of using GPS and total station together in recovering of shaft cross central line with the condition of the damaged nearly well point , and analysis the accuracy of result .Studies show that this method can not only ensure the construction accuracy , improve the construction speed , and also offers a scientific measurement method for wellbore construction meas-ure.%针对近井点被破坏的情况,利用GPS和全站仪联合测量的方法对井筒十字线进行恢复,并对恢复后的精度做了分析。研究表明,该方法不仅能保证施工精度,提高施工速度,并且能为井筒施工测量提供科学的测量方法。

  1. The ATLAS central solenoid

    CERN Document Server

    Yamamoto, A; Ruber, R; Doi, Y; Haruyama, T; Haug, F; ten Kate, H; Kawai, M; Kondo, T; Kondo, Y; Metselaar, J; Mizumaki, S; Olesen, G; Pavlov, O; Ravat, S; Sbrissa, E; Tanaka, K; Taylor, T; Yamaoka, H

    2008-01-01

    The ATLAS detector at the CERN LHC is equipped with a superconducting magnet system consisting of three large toroids and a solenoid. The 2.3 m diameter, 5.3 m long solenoid is located at the heart of the experiment where it provides a 2 T field for spectrometry of the particles emanating from the interaction of the counter-rotating beams of hadrons. As the electromagnetic calorimeter of the experiment is situated outside the solenoid, the coil must be as transparent as possible to traversing particles. The magnet, which was designed at KEK, incorporates progress in technology coming from the development of previous solenoids of this type, in particular that of a new type of reinforced superconductor addressing the requirement of transparency. Special attention has been paid to ensuring reliability and ease of operation of the magnet, through the application of sufficiently conservative guidelines for the mechanical and electrical design, stringent testing during manufacture, and a comprehensive commissioning...

  2. 低压集抄智能化闭环管理模式的研究与应用%Research and Application of Intelligent Closed-loop Management Mode of Low-voltage Centralized Meter-reading

    Institute of Scientific and Technical Information of China (English)

    庄杰; 徐川子; 王晶

    2015-01-01

    基于低压集抄智能化闭环管理模式实现了对采集器关联和电能表轮换的有效管控,同时结合数据库技术,利用掌机直接将现场安装或维修的原始清单以电子稿形式导出,以便对安装或维修数量进行核对,确保表计、采集器的领、配、用数量一致,避免资产流失,实现资产的精细化管理。该管理模式全面实施后,真正实现了低压集抄系统工单下装、派工、安装以及故障处理信息上装的全过程无纸化智能作业,提高了工作效率。%The basic intelligent closed-loop management mode of low-voltage centralized meter-reading effec-tively controls the collector correlation and the energy meter alternation. Combining with database technology, it can export the site installation original lists directly in the form of electronic version using a handheld con-sole to check the quantity of installation or maintenance quickly and ensure the uniform number of collection, distribution as well as use of the meters and collectors to avoid assets loss and implement refined management of assets. Since the management mode is fully implemented, it really realizes the whole process intelligent work including work orders downloading, dispatching, installation and troubleshooting information uploading of the low-voltage centralized meter-reading system and improves the work efficiency.

  3. Centralized versus Decentralized Information Systems

    Science.gov (United States)

    Hugoson, Mats-Åke

    This paper brings into question whether information systems should be centralized or decentralized in order to provide greater support for different business processes. During the last century companies and organizations have used different approaches for centralization and decentralization; a simple answer to the question does not exist. This paper provides a survey of the evolution of centralized and decentralized approaches, mainly in a Nordic perspective. Based on critical reflections on the situation in the end of the century we can discuss what we can learn from history to achieve alignment between centralized and decentralized systems and the business structure. The conclusion is that theories, management and practice for decisions on centralization or decentralization of information systems must be improved. A conscious management and control of centralization /decentralization of IT support is a vital question in the company or the organization, and this is not a task that can be handled only by IT-specialists. There is a need for business oriented IT management of centralization/decentralization.

  4. Betweenness centrality profiles in trees

    CERN Document Server

    Fish, Benjamin; Turan, Gyorgy

    2016-01-01

    Betweenness centrality of a vertex in a graph measures the fraction of shortest paths going through the vertex. This is a basic notion for determining the importance of a vertex in a network. The k-betweenness centrality of a vertex is defined similarly, but only considers shortest paths of length at most k. The sequence of k-betweenness centralities for all possible values of k forms the betweenness centrality profile of a vertex. We study properties of betweenness centrality profiles in trees. We show that for scale-free random trees, for fixed k, the expectation of k-betweenness centrality strictly decreases as the index of the vertex increases. We also analyze worst-case properties of profiles in terms of the distance of profiles from being monotone, and the number of times pairs of profiles can cross. This is related to whether k-betweenness centrality, for small values of k, may be used instead of having to consider all shortest paths. Bounds are given that are optimal in order of magnitude. We also pre...

  5. Application of interventional techniques on central venous catheter related diseases in hemodialysis patients%介入技术在血液透析患者中心静脉导管相关问题中的应用

    Institute of Scientific and Technical Information of China (English)

    杨涛; 侯西彬; 詹申; 王新玲; 王玉柱

    2015-01-01

    目的总结介入技术在血液透析患者中心静脉导管相关性问题诊断及治疗中的应用。方法回顾性分析我院肾内科82例中心静脉导管相关性介入诊断、治疗患者的临床资料,包括导管置入、导管位置调整及单纯诊断性造影,总结导管纤维鞘的诊断和介入处理方法。结果本组中伴有糖尿病者33例(40.2%),既往平均置管次数(3.2±1.7)次;介入下置管共55例次,导管位置调整24例次。置管的患者中,造影提示38例患者存在中心静脉狭窄或闭塞;导管调整的患者均为颈内静脉置管,13例为左侧颈内静脉置管,导管调整的原因多为导管末端不能达到适当的位置;经造影诊断纤维鞘13例次。结论 X线介入下中心静脉导管相关操作可实时明确中心静脉情况,确保导管置入适当位置,并可对病变的中心静脉治疗后置入导管,也是导管纤维鞘的诊断和处理的有效方法之一。%Objective To summarize the interventional therapy on central venous catheter related diseases in hemodialysis patients. Methods We retrospectively analyzed the clinical data of 82 patients who had received interven-tional therapy for catheter related diseases. The data was consisted of catheter insertion under the X ray, adjustment to the catheter and angiography for the catheter related diagnostic procedures. We also summarized the interventional diagnosis and therapy for catheter related fibrin sheath formation. Results The incidence of diabetes mellitus was 40.2%. On an av-erage, previous cannulation times was 3.2±1.7. The number of cannulation and adjustment to the catheter under X ray was 55 and 24 respectively. In all cannulation patients, venography revealed that central venous stenosis or obstruction were found in 38 patients. In patients whose catheter position was adjusted, the sites of puncture were internal jugular vein in all. Puncture sites were left internal jugular

  6. 案例教学法在中枢神经解剖学教学中的应用%Application of case method in central nervous system anatomy teaching

    Institute of Scientific and Technical Information of China (English)

    谭刚; 覃能武; 王振富

    2009-01-01

    Objective To reinforce the training of medical students'clinical thinking ability in the stage of learning basic medicine.Methods Case method was introduced into central nervous system anatomy teaching and questionnaires was made accordingly.Results Answers to questionnaires revealed that it had remarkable effects on improving students'ability of clinical logical thinking,inductive analysis,combining basic theoretical knowledge with clinical practice and self-learning,etc.Conclusions Case method was conducive to students'understanding and absorption of knowledge,and could stimulate students'enthusiasm and initiative in learning central nervous system anatomy.It was also effective in realizing the two-way infiltration of basic medical theories and clinical knowledge,thus to enable the students to initially set up the concept of disease and strengthen the cultivation of students'clinical thinking ability.%目的 在基础医学学习阶段加强医学生临床思维能力培养.方法 将案例教学法引入中枢神经解剖学教学中,设计问卷就教学效果对学生进行调查.结果 案例教学法对提高学生的临床逻辑思维能力、归纳分析能力、基础理论知识与临床实践相结合能力、自学能力等有着较好的效果.结论 运用案例教学法有利于学生对知识的理解和吸收,能够激发学生学习中枢神经解剖学的积极性和主动性,可以有效地实现医学基础理论与临床知识的"双向渗透",使学生初步建立起疾病的概念,从而加强其临床思维能力的培养.

  7. 浅谈网上银行在地勘单位资金集中管理中的应用%Discussion on Application of Internet Banking to the Centralized Management of Funds in Geological Prospecting Units

    Institute of Scientific and Technical Information of China (English)

    周红涛

    2014-01-01

    Internet banking has provide new ideas and ways for ensuring safe and efficient centralized management of funds in geological prospecting units. This means that through internet banking we have achieved bank-enterprise interconnection. By using internet technical operation, we have changed the traditional way of banking ifnancial services. By adopting the pattern of “tree group accounts”we have realized the centralized management. This paper goes on to look at that through internet banking the fund supervision that geological prospecting units performed to their branches has been enhanced. As a result, the efifciency of accounting work and the ifnancial management level have been increased, thus reducing the ifnancial costs. On this basis, this paper points out that in order to reduce the external risk of online banking, we must choose safe and reliable correspondent banks with mature technology. We must choose secure network and authentication medium so as to ensure a secured login. At the same time, a standard operational process and reasonable operation permission should be established so as to ensure the safe usage of online banking. In addition, strict internal accounting control system should be formulated so as to guard against online banking risk.%网上银行为确保地勘单位资金集中管理的安全高效提供了新思路和途径。通过网上银行实现了“银企互联”;利用Internet技术操作,改变了传统的银行金融服务方式;采用“树状集团开户”的模式,实现资金的集中管理。网上银行加强了地勘单位对各分支机构的资金监管、提高了会计工作效率和财务管理水平、降低了财务费用。选择安全可靠、技术成熟的代理银行,降低网上银行外部风险;选择安全的网络及认证介质,保证网上银行安全登录;建立规范的操作流程和合理的操作权限,保证网上银行安全使用;制定严密的内部会计控制制度

  8. Demographic tensions in Central America.

    Science.gov (United States)

    1986-08-01

    This discussion of Central America focuses on the rapid growth of its population, its stagnating economy, and those countries that are socioeconomically advanced. Between 1950-85 the population of Central America tripled, from 9.1 million to 26. 4 million, due to marked mortality declines and the absence of off-setting fertility declines. The distribution of Central Americas's growing populations sets its population growth apart from that of other developing regions. Currently, almost half of all Central Americans live in cities. Although the average growth rate for Central American countries has fallen and is expected to drop further, the decline does not counterbalance the effect of the absolute rise in population numbers. The average annual growth rate of more than 3% annually in the 1960s fell to about 2.6% in recent years, but this decline is due primarily to socioeconomically advanced Costa Rica and Panama. Central America's age structure further complicates the population crisis. About 43% of Central Americans are under the age of 15. When the increasingly larger young population group enters it reproductive years, the potential for future growth (albeit the falling rate of population increase) is unparalleled. UN population projections show the region's population at 40 million by the year 2000. The 1973 oil crisis began a downward spiral for the buoyant post World War II Central American economy. Between 1950-79, real per capita income growth in Central America doubled, with Central American economies growing an average of 5.3% annually. By the early 1980s, overseas markets of the trade-dependent countries of Central America had dried up due to protectionism abroad and slumping basic commodity prices. These and other factors plunged Central America into its current economic malaise of falling real per capita income, rising unemployment, curtailed export led economic growth, and a rising cost of living. In general, economic growth in Central America

  9. PBL在人体中枢神经解剖学教学中的应用%Application of problem-based learning in the teaching practice of human central nervous system anatomy

    Institute of Scientific and Technical Information of China (English)

    欧阳长杰; 曲德伟; 王德广

    2012-01-01

    This paper introduced the scheme,form and measures of implementing problem-based learning in the teaching practice of human central nervous system anatomy.This paper discussed on the depth and scope of the issue,how to mobilize the enthusiasm of the students in the process of discussion,how to be conscious of curriculum knowledge system and logic in the teaching process,how to make students expose to clinical at early stage,how to provide corresponding assessment methods and other aspects of the practice in an aim to help peers to improve the teaching practice.%介绍在人体中枢神经解剖学课程教学中实施以问题为基础的学习(problem-based learning,PBL)的具体方案、形式和措施.并探讨拟定讨论问题的深度与范围,在学生讨论过程中如何调动其积极性,教师在教学过程中如何注意课程知识的系统性和逻辑性,如何让学生早期接触临床,如何配套相应的考核方式等.

  10. GC-MS/MS survey of collision-induced dissociation of tert-butyldimethylsilyl-derivatized amino acids and its application to (13)C-metabolic flux analysis of Escherichia coli central metabolism.

    Science.gov (United States)

    Okahashi, Nobuyuki; Kawana, Shuichi; Iida, Junko; Shimizu, Hiroshi; Matsuda, Fumio

    2016-09-01

    Stable isotope labeling experiments using mass spectrometry have been employed to investigate carbon flow levels (metabolic flux) in mammalian, plant, and microbial cells. To achieve a more precise (13)C-metabolic flux analysis ((13)C-MFA), novel fragmentations of tert-butyldimethylsilyl (TBDMS)-amino acids were investigated by gas chromatography-tandem mass spectrometry (GC-MS/MS). The product ion scan analyses of 15 TBDMS-amino acids revealed 24 novel fragment ions. The amino acid-derived carbons included in the five fragment ions were identified by the analyses of (13)C-labeled authentic standards. The identification of the fragment ion at m/z 170 indicated that the isotopic abundance of S-methyl carbon in methionine could be determined from the cleavage of C5 in the precursor of [M-159](+) (m/z 218). It was also confirmed that the precision of (13)C-MFA in Escherichia coli central carbon metabolism could be improved by introducing (13)C-labeling data derived from novel fragmentations. Graphical Abstract Novel collision-induced dissociation fragmentations of tert-butyldimethylsilyl amino acids were investigated and identified by GC-MS/MS.

  11. Application Examples of Heat Pump Central Air Conditioning of Water Source of Poyang Lake%鄱阳湖水源热泵中央空调运用实例

    Institute of Scientific and Technical Information of China (English)

    曾宇军

    2014-01-01

    Through the selection of model test of central air conditioning cooling and heating mode of Poyang Lake, the author introduces the composition and operation of lake water source heat pump and ground source ground principle coupled heat exchanger auxiliary heating system, analyzing the system operation ef iciency, which has obtained the good use ef ect, and providing a theoretical basis and examples of templates for water source heat pump project in Poyang Lake region.%通过鄱阳湖模型试验研究基地中央空调供冷供热方式的比选,介绍了湖水源热泵和地源土壤耦合换热器辅助供热系统组成和运行原理,进行了该系统运行的效益分析,取得了较好的使用效果,为环鄱阳湖区域利用水源热泵工程提供了理论依据和实例样板。

  12. PACS在中枢神经系统影像学教学中的应用%PACS in the application of imaging teaching in the central nervous system

    Institute of Scientific and Technical Information of China (English)

    徐胜生; 赵菁

    2012-01-01

    目的 运用PACS促进中枢神经系统影像学教学.方法 50名医学影像专业本科生按PACS入门培训、练习后处理显示脑动脉狭窄及动脉瘤、按疾病名称检索及浏览教学图片库的方法来学习中枢神经系统影像内容.结果 学生能高效地掌握所学的内容,并增强学习的主动性和创造性.结论 PACS在中枢神经系统影像学教学中具有重要价值.%Objective To improve imaging teaching of the central nervous system ( CNS ) by applying picture archiving and communication system ( PACS ).Methods Fifty medical imaging undergraduate students were arranged to study the content of CNS by introduction training about PACS,postprocess viewing cerebral stenosis and aneurysm by practicing,studying by searching the disease and browsing teaching picture archiving.Results Students could master the content efficiently and enhance their initiative and creativity.Conclusion PACS has an important value in the imaging teaching of CNS.

  13. The Application of Box–Cox Transformation to Determine the Standardised Precipitation Index (SPI, the Standardised Discharge Index (SDI and to Identify Drought Events: Case Study in Eastern Kujawy (Central Poland

    Directory of Open Access Journals (Sweden)

    Bartczak Arkadiusz

    2014-10-01

    Full Text Available The article presents the results of research into the transformation of series of hydro-meteorological data for determining dry periods with the Standardised Precipitation Index (SPI and the Standardised Discharge Index (SDI. Time series from eight precipitation stations and five series of river discharge data in Eastern Kujawy (central Poland were analysed for 1951–2010. The frequency distribution of the series for their convergence with the normal distribution was tested with the Shapiro–Wilk test and homogeneity with the Bartlett's test. The transformation of the series was done with the Box–Cox technique, which made it possible to homogenise the series in terms of variance. In Poland, the technique has never been used to determine the SPI. After the transformation the distributions of virtually all series complied with the normal distribution and were homogeneous. Moreover, a statistically significant correlation between the δ transformation parameter and the skewness of the series of monthly precipitation was observed. It was similar for the series of mean monthly discharges in the winter half-year and the hydrological year. The analysis indicates an alternate occurrence of dry and wet periods both in case of precipitation and run-offs. Drought periods coincided with low flow periods. Thus, the fluctuations tend to affect the development of agriculture more than long-term ones.

  14. Research, methodology, and applications of probabilistic seismic-hazard mapping of the Central and Eastern United States; minutes of a workshop on June 13-14, 2000, at Saint Louis University

    Science.gov (United States)

    Wheeler, Russell L.; Perkins, David M.

    2000-01-01

    The U.S. Geological Survey (USGS) is updating and revising its 1996 national seismic-hazard maps for release in 2001. Part of this process is the convening of four regional workshops with earth scientists and other users of the maps. The second of these workshops was sponsored by the USGS and the Mid-America Earthquake Center, and was hosted by Saint Louis University on June 13-14, 2000.The workshop concentrated on the central and eastern U.S. (CEUS) east of the Rocky Mountains. The tasks of the workshop were to (1) evaluate new research findings that are relevant to seismic hazard mapping, (2) discuss modifications in the inputs and methodology used in the national maps, (3) discuss concerns by engineers and other users about the scientific input to the maps and the use of the hazard maps in building codes, and (4) identify needed research in the CEUS that can improve the seismic hazard maps and reduce their uncertainties. These minutes summarize the workshop discussions. This is not a transcript; some individual remarks and short discussions of side issues and logistics were omitted. Named speakers were sent a draft of the minutes with a request for corrections of any errors in remarks attributed to them. Nine people returned corrections, amplifications, or approvals of their remarks as reported. The rest of this document consists of the meeting agenda, discussion summaries, and a list of the 60 attendees.

  15. The Central Trigger Processor (CTP)

    CERN Multimedia

    Franchini, Matteo

    2016-01-01

    The Central Trigger Processor (CTP) receives trigger information from the calorimeter and muon trigger processors, as well as from other sources of trigger. It makes the Level-1 decision (L1A) based on a trigger menu.

  16. Payments and Central Bank Policy

    DEFF Research Database (Denmark)

    Korsgaard, Søren

    This thesis consists of three chapters. The rst, "Paying for Payments", examines the role of interchange fees in payment card networks. The second, "Bank Liquidity and the Interbank Market" (co-authored with Mikael Reimer Jensen), investigates how banks' liquidity holdings at the central bank a ect...... outcomes in the money market. The third, "Collateralized Lending and Central Bank Collateral Policy", considers the emergence of credit constraints under collateralized lending, and how central banks use collateral policy to mitigate these constraints. While the chapters can be read independently......, they share common themes. Each chapter is concerned with payments in one way or another, each is concerned with the e ciency of market outcomes, and, to the extent that there is scope for improving these outcomes, each discusses the appropriate role for policy, in particular central bank policy....

  17. Central cementifying fibroma of mandible

    Directory of Open Access Journals (Sweden)

    Joseph Edward

    2010-01-01

    Full Text Available Central cementifying fibroma is a rare non odontogenic tumor coming in the group of fibro osseouslesion, arising from periodontal ligament and is usually seen in tooth bearing area. It can affect boththe mandible and the maxilla, particularly the mandible. This bone tumour consists of highly cellular,fibrous tissue that contains varying amounts of calcified tissue resembling bone, cementum or both.Here we present a case of Central cementifying fibroma (recurrent in a 34 year old female.

  18. Inferring Centrality from Network Snapshots

    OpenAIRE

    Haibin Shao; Mehran Mesbahi; Dewei Li; Yugeng Xi

    2017-01-01

    The topology and dynamics of a complex network shape its functionality. However, the topologies of many large-scale networks are either unavailable or incomplete. Without the explicit knowledge of network topology, we show how the data generated from the network dynamics can be utilised to infer the tempo centrality, which is proposed to quantify the influence of nodes in a consensus network. We show that the tempo centrality can be used to construct an accurate estimate of both the propagati...

  19. CENTRAL PLATEAU REMEDIATION OPTIMIZATION STUDY

    Energy Technology Data Exchange (ETDEWEB)

    BERGMAN, T. B.; STEFANSKI, L. D.; SEELEY, P. N.; ZINSLI, L. C.; CUSACK, L. J.

    2012-09-19

    THE CENTRAL PLATEAU REMEDIATION OPTIMIZATION STUDY WAS CONDUCTED TO DEVELOP AN OPTIMAL SEQUENCE OF REMEDIATION ACTIVITIES IMPLEMENTING THE CERCLA DECISION ON THE CENTRAL PLATEAU. THE STUDY DEFINES A SEQUENCE OF ACTIVITIES THAT RESULT IN AN EFFECTIVE USE OF RESOURCES FROM A STRATEGIC PERSPECTIVE WHEN CONSIDERING EQUIPMENT PROCUREMENT AND STAGING, WORKFORCE MOBILIZATION/DEMOBILIZATION, WORKFORCE LEVELING, WORKFORCE SKILL-MIX, AND OTHER REMEDIATION/DISPOSITION PROJECT EXECUTION PARAMETERS.

  20. Controlling centrality in complex networks

    CERN Document Server

    Nicosia, Vincenzo; Romance, Miguel; Russo, Giovanni; Latora, Vito

    2011-01-01

    Spectral centrality measures allow to identify influential individuals in social groups, to rank Web pages by their popularity, and even to determine the impact of scientific researches. The centrality score of a node within a network crucially depends on the entire pattern of connections, so that the usual approach is to compute the node centralities once the network structure is assigned. We face here with the inverse problem, that is, we study how to modify the centrality scores of the nodes by acting on the structure of a given network. We prove that there exist particular subsets of nodes, called controlling sets, which can assign any prescribed set of centrality values to all the nodes of a graph, by cooperatively tuning the weights of their out-going links. We show that many large networks from the real world have surprisingly small controlling sets, containing even less than 5-10% of the nodes. These results suggest that rankings obtained from spectral centrality measures have to be considered with ex...

  1. Application of visual management flow diagram in management of central sterile supply department%目视流程图解在提高消毒供应室管理中的应用

    Institute of Scientific and Technical Information of China (English)

    赵卫萍; 张红超; 庹琨明; 杨涛; 孟玲; 李环

    2015-01-01

    OBJECTIVE To improve the scientific management of central sterile supply department and work quality through the visual management flow diagram .METHODS The visual flow management team was established to de‐velop the visual flow diagram and organize all the staff to learn the concepts ,requirements ,and contents of the visual management flow diagram ,which was served as one of the onsite management modes and was applied for the management of the instruments ,infection control ,and instrument packages .RESULTS As compared with the qualified rate of the instruments in Jul-Sep ,2013 ,it was increased in Jul-Sep ,2014 .The qualified rate of quali‐ty examination of instruments was 97 .57% in 2013 ,99 .75% in 2014 ;the qualified rate of number of instrument packages was 95 .21% in 2013 ,99 .55% in 2014 ;the qualified rate of infection control was 94 .00% in 2013 , 98 .49% in 2014 ;the qualified rate of timely supply of instruments was 95 .80% in 2013 ,99 .44% in 2014 . CONCLUSIONS The visual flow diagram can achieve significant effect on actual management of the central sterile supply department ,raise the work quality and efficiency of the departments ,and make the work flow of the supply department standardized ,the quality control and teaching training visualized;it is a visualized ,high‐efficiency flow management mode .%目的:通过目视流程图解在消毒供应室中的应用,提高供应室科学化管理水平和工作质量。方法科室成立目视流程管理小组,制作目视流程图解,组织全科人员学习目视管理流程图解的概念、要求和内容,将其作为现场管理的模式之一,应用于仪器设备、感染控制、器械包管理。结果器械合格率2013年7-9月与2014年7-9月相比均有提高,其中器械质量检查、器械包装数量、感染控制、器械及时供应等合格率,2013年分别为97.57%、95.21%、94.00%、95.80%;2014年分别为99.75%、99.55%、98

  2. Deformation of erosive and accretive forearcs during subduction of migrating and non-migrating aseismic ridges: Results from 3-D finite element models and application to the Central American, Peruvian, and Ryukyu margins

    Science.gov (United States)

    Zeumann, Stefanie; Hampel, Andrea

    2015-09-01

    Subduction of aseismic oceanic ridges causes considerable uplift and deformation of the upper plate and may lead, for example, to the indentation of the forearc, the formation of marine terraces, or distinct fault patterns in the upper plate. Depending on the orientation of the ridge relative to the plate convergence direction, the ridge may either be stationary or migrate along the margin. Here we use three-dimensional numerical models to investigate the tectonic evolution of forearcs affected by ridge subduction. In different experiments, we distinguish between migrating/non-migrating ridges and accretive/erosive margins, respectively. Our results reveal that displacement and strain fields above migrating and non-migrating ridges are asymmetric with respect to the ridge axis unless both ridge and plate convergence direction are perpendicular to the trench. As the asymmetric deformation pattern shifts along the margin through time, uplift caused by the underthrusting ridge is followed by subsidence when the ridge crest passed by, and regions initially experiencing shortening may subsequently undergo extension and vice versa. If the forearc comprises an accretionary prism, the ridge-induced reentrant is larger than those in models with erosive forearcs and strain localizes in the frontal part of the wedge. Additional models with a setup adjusted to the Cocos and Gagua Ridges provide constraints on the onset of their subduction at the Central American and Ryukyu margins at ~2 Ma and 1 Ma, respectively. Displacement and strain fields from a model for the Nazca Ridge collision zone show good agreement with geological data from marine terraces and Quaternary faulting.

  3. Improvement and application of centralized air supplying system for cigarette makers%卷接机组集中工艺风力系统的改造与应用

    Institute of Scientific and Technical Information of China (English)

    黄深海; 周奇峰; 马臣; 张振峰; 袁国安

    2013-01-01

    对集中工艺风力系统将风力合理分配到每台卷接机组,并根据其自身状态实现风力自动平衡进行了研究。采用PLC和PROFIBUS-DP现场总线控制技术,构建工艺风力自动平衡控制系统,确保卷接机组所需工艺风力连续、有效、稳定的供给。以贵州省某卷烟厂卷包A车间4组卷接机组构建的集中工艺风力与除尘系统平衡控制技术的应用为例,探讨了其集中工艺风力平衡经济型控制系统的构成和应用效果。通过与其它平衡控制模式的比较,得出风力平衡经济型控制系统具有一定的实用性和推广价值。%The air supplying reasonable assigned to each unit in the centralized air supplying system, and achieve homeostasis were studied according to its own state. The PLC and the PROFIBUS-DP BUS control technology has been used, which helps air supply continuously, efficaciously and stably. As the example of 4 cigarette makers in a cigarette factory in Guizhou Province, the composing and effect of economic control system of air supplying system and its uses of balance control technology in dust removal system were analyzed. Compared with other systems, it was concluded that this technology offered many advantages and it was beneficial to technology elevation in middle or small cigarette factories. It has certain practicability and popularization value.

  4. The application of terrestrial laser scanner and SfM photogrammetry in measuring erosion and deposition processes in two opposite slopes in a humid badlands area (central Spanish Pyrenees)

    Science.gov (United States)

    Nadal-Romero, E.; Revuelto, J.; Errea, P.; López-Moreno, J. I.

    2015-08-01

    Erosion and deposition processes in badland areas are usually estimated using traditional observations of topographic changes, measured by erosion pins or profile metres (invasive techniques). In recent times, remote-sensing techniques (non-invasive) have been routinely applied in geomorphology studies, especially in erosion studies. These techniques provide the opportunity to build high-resolution topographic models at centimetre accuracy. By comparing different 3-D point clouds of the same area, obtained at different time intervals, the variations in the terrain and temporal dynamics can be analysed. The aim of this study is to assess and compare the functioning of terrestrial laser scanner (TLS, RIEGL LPM-321) and structure-from-motion photogrammetry (SfM) techniques (Camera FUJIFILM, Finepix x100 and software PhotoScan by AgiSoft) to evaluate erosion and deposition processes in two opposite slopes in a humid badlands area in the central Spanish Pyrenees. Results showed that TLS data sets and SfM photogrammetry techniques provide new opportunities in geomorphological erosion studies. The data we recorded over 1 year demonstrated that north-facing slopes experienced more intense and faster changing geomorphological dynamics than south-facing slopes as well as the highest erosion rates. Different seasonal processes were observed, with the highest topographic differences observed during winter periods and the high-intensity rainfalls in summer. While TLS provided the highest accuracy models, SfM photogrammetry was still a faster methodology in the field and precise at short distances. Both techniques present advantages and disadvantages, and do not require direct contact with the soil and thus prevent the usual surface disturbance of traditional and invasive methods.

  5. Application of bronchoscopy in etiological diagnosis of central airway obstruction%支气管镜在中央气道阻塞性病变的病因诊断中的应用

    Institute of Scientific and Technical Information of China (English)

    陈为忠; 谢伟见; 付敏; 曹惠红

    2012-01-01

    目的 探讨中央气道阻塞性病变的病因、临床特点及支气管镜检查、治疗的必要性和价值.方法 回顾性分析2008年2月至2011年12月就诊于我院呼吸科的中央气道阻塞性病变患者42例,归纳其临床特点、影像学表现、支气管镜镜检及活检病理.结果 42例气道阻塞性病变患者中,男30例,女12例,年龄19~81岁,中位年龄56岁,其中支气管鳞癌12例(12/42),腺癌6例(6/42),小细胞肺癌10例(10/42),气管、支气管内膜结核4例(4/42),慢性炎症导致黏液痰栓4例(4/42),食管鳞癌2例(2/42),管腔内异物1例(1/42),支气管结石2例(2/42),肺囊肿并出血包裹1例(1/42);42例患者中有咳嗽症状38例,咯血16例,气短或呼吸困难14例,胸痛8例;所有患者均行胸部CT检查,18例行气道三维重建,40例发现病灶或病灶间接征象;42例患者均行支气管镜检查,发现病变或可疑病变,34例为气道内器质性病变,在支气管镜检查中使用活检钳取得组织标本,初次病理阳性率为100%;38例行肺功能检查,其中26例可见阻塞性或混合性通气功能障碍,6例见流速-容量环平台.结论 中央气道阻塞病因复杂,以恶性病变为主,常见症状为咳嗽、呼吸困难、咯血、胸痛、消瘦、乏力,无特异性表现;胸部CT联合气道重建表现为阻塞性肺炎,阻塞性肺不张,阻塞性肺气肿为主;气管镜及活检病理为诊断提供准确信息,对病因诊断有无可替代的价值;根据不同病因及不同病变部位选择不同的内、外科治疗方法.%Objective To analyse the cause and clinical characteristics of central airway G and assess necessity and value of bronchoscopy.Methods We performed retrospective analytical study in the patients with central airway obstruction enrolled at the Department of respiratory disease in our hospital from February 2008 to December 2011 by summarizing the clinical features,imaging,bronchoscopy and biopsy.Results Within 42

  6. Central Facilities Area Sewage Lagoon Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Mark R. Cole

    2013-12-01

    The Central Facilities Area (CFA), located in Butte County, Idaho, at the Idaho National Laboratory has an existing wastewater system to collect and treat sanitary wastewater and non-contact cooling water from the facility. The existing treatment facility consists of three cells: Cell #1 has a surface area of 1.7 acres, Cell #2 has a surface area of 10.3 acres, and Cell #3 has a surface area of 0.5 acres. If flows exceed the evaporative capacity of the cells, wastewater is discharged to a 73.5-acre land application site that uses a center-pivot irrigation sprinkler system. As flows at CFA have decreased in recent years, the amount of wastewater discharged to the land application site has decreased from 13.64 million gallons in 2004 to no discharge in 2012 and 2013. In addition to the decreasing need for land application, approximately 7.7 MG of supplemental water was added to the system in 2013 to maintain a water level and prevent the clay soil liners in the cells from drying out and “cracking.” The Idaho National Laboratory is concerned that the sewage lagoons and land application site may be oversized for current and future flows. A further concern is the sustainability of the large volumes of supplemental water that are added to the system according to current operational practices. Therefore, this study was initiated to evaluate the system capacity, operational practices, and potential improvement alternatives, as warranted.

  7. Central Limit Theorems for Multicolor Urns with Dominated Colors

    CERN Document Server

    Berti, Patrizia; Pratelli, Luca; Rigo, Pietro

    2009-01-01

    An urn contains balls of d colors. At each time, a ball is drawn and then replaced together with a random number of balls of the same color. Assuming that some colors are dominated by others, we prove central limit theorems. Some statistical applications are discussed.

  8. Engineering of data base application to control room in operation plant; Reingemieria de la aplicacion de la base de datos del conexionado de los aparatos de los paneles de mando de la sala de control de una central en operacion

    Energy Technology Data Exchange (ETDEWEB)

    Vallier Pino, J.; Fernandez Garcia, N. C.; Tielas Reina, M.

    2004-07-01

    The large number of Setpoints and associated allowable values that have to be determined in a nuclear power plant prompted EMPRESARIOS AGRUPADOS to develop the AVACO program to computerise and optimise the calculation process. This application has been developed based on Microsoft Access 97 database and Mathsoft Mathcad 8 calculation program. The calculation methodology used by AVACO complies with the procedures and criteria established in Regulatory Guide 1.105, issue 3, dated December 1999, Setpoints for Safety-Related Instrumentation, and in standard ISA-S67.04.01-2000. The computerised calculation of nominal trip points and allowable values for trip functions saves time, prevents possible errors which are more likely to occur in manual calculation, and allows adequate control of input data and results. The database contains all input data and associated references required for calculation, as well as the calculation results. This integration enables the quick and efficient handling, storage and updating of large volumes of data required for calculation. Mathcad 8 performs the calculations using templates created for different measuring channel configurations. Said templates define in text form the formulae used. Following the manual introduction of input data into the database, these data are automatically transferred to the corresponding spreadsheet template; the calculation results are then automatically incorporated back into the database. EMPRESARIOS AGRUPADOS and TECNATOM are currently using this application the Calculation of Setpoints for the Lungmen Nuclear Power Plant project.

  9. Core reactor simulation of the Central Laguna Verde (CLV) reactor in stationary state and an example of the application in the recharge options analysis of cycle 3; Simulacion del nucleo del reactor de la Central Laguna Verde (CLV) en estado estacionario y ejemplo de aplicacion en el analisis de alternativas de recarga del ciclo 3

    Energy Technology Data Exchange (ETDEWEB)

    Ocampo Mansilla, Hector; Francois Lacouture, Juan Luis; Blanco Lara, Jesus; Cortes Campos, Carlos Cristobal; Esquivias Montoya, Jesus; Esquivel Torres, Jose Luis; Martin del Campo Marquez, Cecilia [Instituto de Investigaciones Electricas, Cuernavaca (Mexico); Montes Tadeo, Jose Luis [Instituto Nacional de Investigaciones Nucleares (ININ), Salazar (Mexico); Sanchez Herrera, Luciano; Torres Alvarez, Carlos [Comision Federal de Electricidad (CFE), Mexico, D. F. (Mexico)

    1991-12-31

    The results are presented of a study requested by Comision Federal de Electricidad (CFE) for the analysis of Cycle 3, of Unit No. 1 of the Laguna Verde Nuclear Power Station (CLNV) and determine the burning effect impact, carried out with the starting tests and the operation of Cycles 1 and 2 on base of the cycle extension known as coastdown. The calculations were realized with the Code Package FMS for fuel managing, using the Code PRESTO-B that analyzes the reactor in detailed form in three dimensions an in stationary state. In the study the schemes of fraction of recharge proposed by General Electric (GE) were analyzed with the effect of cycle extension. The initial design value of 100 assemblies for Cycle 3, GE proposes to increase such fraction from 112 to 120 assemblies. This impacts the cost of the second recharge and the purpose of this investigation is to analyze options with higher fuel enrichment in U-235 to minimize the number of assemblies in this recharge. The analyses effected show that the designs proposed by GE do not fulfill the required energy proposed for the cycle, even using in the recharge only fuel with 3.03% of enrichment. It is proposed, likewise, the fuel enrichment up to 3.25% to satisfy the energy demand with a minimum of assemblies. [Espanol] Se presentan los resultados de un estudio solicitado por la Comision Federal de Electricidad (CFE) para analizar el ciclo 3, de la unidad 1 de la Central Laguna Verde (CLV), y determinar el impacto del efecto de quemado llevado a cabo con las pruebas de arranque y por la operacion de los ciclos 1 y 2 con base en la tecnica de alargamiento del ciclo conocida como coastdown1. Los calculos se realizaron con el paquete de codigos FMS para la administracion de combustible, usando el codigo PRESTO-B que analiza el reactor en forma detallada en tres dimensiones y en estado estacionario. Se analizaron en el estudio los esquemas de fraccion de recarga propuesta por la General Electric (GE) con el efecto de

  10. Rosette Central Configurations, Degenerate central configurations and bifurcations

    CERN Document Server

    Lei, Jinzhi

    2009-01-01

    In this paper we find a class of new degenerate central configurations and bifurcations in the Newtonian $n$-body problem. In particular we analyze the Rosette central configurations, namely a coplanar configuration where $n$ particles of mass $m_1$ lie at the vertices of a regular $n$-gon, $n$ particles of mass $m_2$ lie at the vertices of another $n$-gon concentric with the first, but rotated of an angle $\\pi/n$, and an additional particle of mass $m_0$ lies at the center of mass of the system. This system admits two mass parameters $\\mu=m_0/m_1$ and $\\ep=m_2/m_1$. We show that, as $\\mu$ varies, if $n> 3$, there is a degenerate central configuration and a bifurcation for every $\\ep>0$, while if $n=3$ there is a bifurcations only for some values of $\\epsilon$.

  11. 集中空调冷凝热回收技术在生活热水供应系统中的应用%Application of central air conditioning condense heat recovery technology to domestic hot water supply system

    Institute of Scientific and Technical Information of China (English)

    黄璞洁; 李艳霞; 何耀炳; 许伊那

    2011-01-01

    介绍\t了空调冷凝热回收技术的工作原理,计算确定了冷凝热回收机组和蓄热水箱的容量,并与传统的空调和生活热水供应系统进行比较.探讨了空调冷凝热回收技术在生活热水供应系统中的设计应用.%Based on the working principle, calculates the capacity of the condense heat recovery unit and heat storage water tank, and compares with the traditional air conditioning and domestic hot water supply system. Discusses the application of air conditioning condense heat recovery technology to the design of domestic hot water supply system.

  12. 改良PICC置管技术在169例肺癌患者化疗中的应用%Application of the improved peripherally inserted central career technique in chemotherapy for 169 patients with lung cancer

    Institute of Scientific and Technical Information of China (English)

    郭梅; 田明珠; 汪丹; 王鑫; 龚海芬

    2009-01-01

    目的 研究改良经外周静脉置人中心静脉导管(PICC)置管技术对导管异位的影响.方法 将169例肺癌置管患者随机分为试验组(88例)与对照组(81例),试验组在行PICC置管术送管至25 cm时,助手用手紧贴患者锁骨上窝按压穿刺侧颈内静脉和颈外静脉下端;对照组采取常规歪头的方法.统计两组导管异位的发生率.结果 试验组仅有1例导管被送入颈外静脉,导管颈部异位发生率为1.1%(1/88);对照组导管异位发生率为11.1%(9/81),两组比较差异无统计学意义(x2=7.3636,P<0.01).结论 肺癌患者PICC置管过程中,术者采取相应的干预手法可明显减少导管异行进入颈静脉的并发症.%Objective To evaluate the influence of pressing technique on the malposition of catheter dur- ing the operation of peripherally inserted central catheter (PICC). Methods Totally, 169 patients with lung cancer were randomly divided into treatment group (n = 88), in which the external and internal jugular veins were pressed at the supraclavicular fossa by the assistant when the catheter was navigated in 25 cm, and control group (n = 81), in which the patients were called to turn their angle of mandible to supraclavicular fossa when the cathe- ter was sent in. Results There were only one patient whose catheter was sent in external jugular vein in treatment group and nine patients whose catheters were sent in external and internal jugular vein in control group. The inci- dence of malposition of catheter was significantly different between two groups (1.1% vs. 11. 1% , X2 =7. 3636, P < 0. 01). Conclusion The pressing technique can reduce the incidence of malposition of catheter into external and internal jugular vein during the operation of PICC.

  13. Equipment Parameters Application Solution Based on the Equipment Centralized Monitoring System and the Equipment Operation and Maintenance Platform%基于设备集中监控系统和设备运维平台的设备参数应用解决方案

    Institute of Scientific and Technical Information of China (English)

    罗科坚

    2014-01-01

    ATC equipment parameters have a great significance to equipment normal operation for the reason that ATC equipment pa-rameters reflect the equipment status. Recording relevant parameters of the daily equipment operation status is an important work of the e-quipment maintenance personnel. Currently, there are many problems such as the high maintenance costs of equipment parameters and low efficiency of manual records, even some missing, mistaken fill records or inevitably appearing non-standard records. In order to solve these problems, this paper presents an equipment parameters application solution based on the equipment centralized monitoring system and the equipment operation and maintenance platform, considering the Central South ATC equipment centralized monitoring system and equipment operation and maintenance platform for the analysis and processing of the equipment parameters, providing a more intuitive graphical showing way for the maintenance personnel, and providing a more intuitive and effective analytical tools. This equipment pa-rameters application solution can help to improve the reliability and accuracy of maintenance of equipment parameters, and reduce costs of equipment operation and maintenance.%空管设备参数反映设备的运行状况,对设备的正常运行具有重要意义。记录设备日常运行的相关参数是设备维护人员的重要工作内容,设备参数的维护成本高,人工记录效率低,漏填、误填或记录不规范的情况不可避免出现等,为了解决这些问题,本文提出一种基于设备集中监控系统和设备运行维护平台的设备参数应用解决方案,综合考虑中南空管设备集中监控系统和设备运行维护平台,对设备参数进行分析处理,以更直观的图形方式展现给使用人员,提供直观有效的分析手段,有利于提高设备参数维护的可靠性和准确性、降低设备运维成本。

  14. Application of the bundle of nursing care in cancer patients with indwel ing thoracic central venous catheter%集束化护理在留置胸腔中心静脉导管肿瘤患者中的应用

    Institute of Scientific and Technical Information of China (English)

    钟文娟; 陈娟; 傅芳芳

    2016-01-01

    Objective:To explore the application method and effect of the bundle of nursing care in cancer patients with indwelling tho-racic central venous catheter.Methods:175 cancer patients with indwelling central venous catheter were randomly divided into the control group(n=88)and the intervention group(n=87).The routine nursing care was taken in the control group and the bundle of nursing care was provided in the intervention group,the effect of nursing care was compared between the two groups.Results:The catheter shedding rate was lower in the intervention group than the control group(P<0.05);the satisfaction rate of the patients was higher than the control group (P<0.05).Conclusion:Application of the bundle of nursing care in cancer patients with indwelling thoracic central venous catheter can effectively reduce the incidence of catheter shedding and improve the patient′s satisfaction.%目的:探讨集束化护理在留置胸腔中心静脉导管肿瘤患者中的应用方法及效果。方法:将175例留置胸腔中心静脉导管肿瘤患者随机分为对照组88例和干预组87例,对照组实施常规护理,干预组实施集束化护理,比较两组护理效果。结果:干预组脱管发生率低于对照组(P<0.05),满意度高于对照组(P<0.05)。结论:集束化护理可有效降低留置胸腔中心静脉导管肿瘤患者的脱管发生率,提高其满意度。

  15. Coverage centralities for temporal networks

    CERN Document Server

    Takaguchi, Taro; Yoshida, Yuichi

    2015-01-01

    Structure of real networked systems, such as social relationship, can be modeled as temporal networks in which each edge appears only at the prescribed time. Understanding the structure of temporal networks requires quantifying the importance of a temporal vertex, which is a pair of vertex index and time. In this paper, we define two centrality measures of a temporal vertex by the proportion of (normal) vertex pairs, the quickest routes between which can (or should) use the temporal vertex. The definition is free from parameters and robust against the change in time scale on which we focus. In addition, we can efficiently compute these centrality values for all temporal vertices. Using the two centrality measures, we reveal that distributions of these centrality values of real-world temporal networks are heterogeneous. For various datasets, we also demonstrate that a majority of the highly central temporal vertices are located within a narrow time window around a particular time. In other words, there is a bo...

  16. Adaptação para a língua Portuguesa e aplicação de protocolo de avaliação das disartrias de origem central em pacientes com Doença de Parkinson Adjustment to the Portuguese and application to patients with Parkinson's disease of protocol within central origin dysarthrias' assessment

    Directory of Open Access Journals (Sweden)

    Angélica Suelen Fracassi

    2011-12-01

    Full Text Available OBJETIVO: traduzir e adaptar protocolo desenvolvido por pesquisadores alemães, adequando-o às características fonéticas e linguísticas do português falado no Brasil. Caracterizar os componentes de fala mais alterados na população com doença de Parkinson, comparando-os com grupo de sujeitos normais na mesma faixa etária. MÉTODOS: realizou-se a tradução e adaptação do protocolo. Posteriormente foram avaliados 21 pacientes com diagnóstico neurológico de Doença de Parkinson nos estágios Hoehn &Yarh, entre 2 e 3, e 10 sujeitos normais. O protocolo incluía avaliação da respiração, fonação, ressonância, articulação, prosódia e a análise acústica dos parâmetros vocais. RESULTADOS: o protocolo mostrou-se de fácil aplicação clínica. Nos sujeitos com doença de Parkinson foram observadas alterações predominantes na fonação (85,9% e articulação (42,9%. CONCLUSÃO: o estudo demonstrou ser o protocolo uma ferramenta eficiente para a avaliação da disartria em pacientes com doença de Parkinson.PURPOSE: to translate and adapt the protocol developed by German researchers, adjusting it to the phonetic and linguistic characteristics of Brazilian Portuguese. Observe the amended speech components in a group of patients with Parkinson's disease, and comparing them with normal subjects in the same age. METHOD: twenty one patients with neurological diagnosis of Parkinson's disease in the Hoehn & Yarh stages (2-3, and 10 control subjects were assessed. The protocol was translated, adjusted and applied to the subjects of both control and Parkinson's disease group, assessing the breathing, phonation, resonance, articulation, prosody and acoustic analysis. RESULTS: in the dysarthria evaluation, the protocol showed to be simple and it presented a fast clinical application. In the subjects with Parkinson's disease, we observed alterations in both phonation (85.9% and articulation (42.9%. CONCLUSION: the study demonstrated that the

  17. Inferring Centrality from Network Snapshots

    Science.gov (United States)

    Shao, Haibin; Mesbahi, Mehran; Li, Dewei; Xi, Yugeng

    2017-01-01

    The topology and dynamics of a complex network shape its functionality. However, the topologies of many large-scale networks are either unavailable or incomplete. Without the explicit knowledge of network topology, we show how the data generated from the network dynamics can be utilised to infer the tempo centrality, which is proposed to quantify the influence of nodes in a consensus network. We show that the tempo centrality can be used to construct an accurate estimate of both the propagation rate of influence exerted on consensus networks and the Kirchhoff index of the underlying graph. Moreover, the tempo centrality also encodes the disturbance rejection of nodes in a consensus network. Our findings provide an approach to infer the performance of a consensus network from its temporal data. PMID:28098166

  18. Application of bark ash to a mixed forest in central Sweden - effects on soil chemistry, composition of the flora and stem growth; Tillfoersel av barkaska till en blandskog i Medelpad - effekter paa markkemi, florans sammansaettning och stamtillvaext

    Energy Technology Data Exchange (ETDEWEB)

    Nilsson, Torbjoern; Nilsson, Aake; Larsson, Kjell

    2004-02-01

    In a 60-year-old mixed coniferous stand dominated by Norway spruce on a sandy-silty till, the effects on soil chemistry, field vegetation and stem growth of applying two different ash products were studied during 1995-2002. Eight field plots (30x30 m) were established in early summer 1995, 56 km WNW Sundsvall in Central Sweden on forest land belonging to SCA Skog. One year later, in June 1996, 3 tonnes of pelleted bark ash (A) from a pulp mill factory were applied per hectare on four of these plots. During the production of these ash pellets, 8-10 % of tall oil was added.The other four plots were control plots (K). In July 1996, six more plots were established, in connection to the other eight plots. Two of these new plots were control plots (C), the other four plots were treated with granules (AS) of bark ash and sewage sludge from A sewage-treatment plant in Sundsvall. Two different doses of these granules were used; two plots received 300 kg per plot or 3.3 tonnes/ha (AS3) and two plots received 900 kg per plot or 10 tonnes/ha (AS9). The field vegetation in treatment A and K was inventoried one year before treatment, and one and five years after treatment. In the other treatments (C, AS3 and AS9) the field vegetation was inventoried only one and five years after treatment. Growth measurements (diameter at breast height and height of the trees) were made in connection to the treatments in June-July 1996 and six years later in May 2002. Soil samplings (humus layer, 0-5 cm below humus layer) were performed six years after the treatments. The soil samples were analyzed on pH, electrical conductivity, organic matter, organic carbon and total nitrogen. Six years after the treatments, considerable more ash pellets than ash granules were found on or in the humus layer. Apparently the ash granules disintegrated faster than the ash pellets. The effects on soil chemistry, six years after treatment, were also more apparent on plots treated with ash granules than on plots

  19. Spatio-temporal Dynamics of Land-use and Land-cover Change: A Multi-agent Simulation Model and Its Application to an Upland Watershed in Central Vietnam

    Science.gov (United States)

    Le, Q.; Vlek, P. L.; Park, S.

    2005-12-01

    flexible interactions among human and landscape agents, and monitors consequent land-use changes and associated socio-economic dynamics. The model was applied in a watershed of about 100 km2 in A-Luoi district, Central Vietnam. Spatially explicit data were obtained from Landsat ETM images, thematic maps, an extensive forest inventory, and an intensive household survey. Field data were used for calibrating agent's parameters and develop an initial database for simulation runs. Scenarios of land-use changes under different policy options on forest protection zoning, agrochemical subsidies and agricultural extension were generated to evaluate the consequences of such policy interventions. Preliminary simulation runs for 10 different policy options suggest that reducing the current proportion of protected area from 90% to 50% and increasing the enforcement of protection, together with the provision of extension services for a third of the total population, and subsidizing 5% of the population with agrochemicals ($US 16 household-1 year-1) would, on average, increase per capita gross income by 15% and significantly reduce forest degradation compared to the scenario based on the status quo (i.e., the policy settings of 2002).

  20. MASSIVE PARALLELISM WITH GPUS FOR CENTRALITY RANKING IN COMPLEX NETWORKS

    Directory of Open Access Journals (Sweden)

    Frederico L. Cabral

    2014-10-01

    Full Text Available Many problems in Computer Science can be modelled using graphs. Evaluating node centrality in complex networks, which can be considered equivalent to undirected graphs, provides an useful metric of the relative importance of each node inside the evaluated network. The knowledge on which the most central nodes are, has various applications, such as improving information spreading in diffusion networks. In this case, most central nodes can be considered to have higher influence rates over other nodes in the network. The main purpose in this work is developing a GPU based and massively parallel application so as to evaluate the node centrality in complex networks using the Nvidia CUDA programming model. The main contribution of this work is the strategies for the development of an algorithm to evaluate the node centrality in complex networks using Nvidia CUDA parallel programming model. We show that the strategies improves algorithm´s speed-up in two orders of magnitude on one NVIDIA Tesla k20 GPU cluster node, when compared to the hybrid OpenMP/MPI algorithm version, running in the same cluster, with 4 nodes 2 Intel(R Xeon(R CPU E5-2660 each, for radius zero.

  1. CENTRAL MECHANISMS OF ACUPUNCTURE ANALGESIA

    Directory of Open Access Journals (Sweden)

    Eman S. Mansour

    2015-12-01

    Full Text Available Background: Acupuncture is an component of traditional Chinese medicine (TCM that has been used for three thousand years to treat diseases and relieve pain. Pain is found to be the most common reason for people to use acupuncture. Due to recent scientific findings, acupuncture treatment has been accepted worldwide. Numerous trials have been conducted especially in analgesia. The mechanisms of acupuncture analgesia has been widely investigated, however, the underlying mechanism still not clear. This article summarizes the central mechanisms of acupuncture analgesia and reviews recent studies on the topic. Method: We have focused on examining the recent literature on acupuncture analgesia. The central mechanisms of acupuncture analgesia and reviews recent studies on the topic. We focused on the studies related to central mechanisms of acupuncture analgesia from these aspects: (neurophysiology, neurochemistry and neuroanatomy. Result: The result revealed that acupuncture act on various parts of the central nervous system, including the spinal cord, brain stem, cerebral ganglia and cerebral cortex to alleviate pain. The central mechanisms underlying the effects of acupuncture include neurohumors and neurotransmitters, which are involved in analgesia. At spinal level, Spinal opioids, glutamate, norepinephrine and serotonin are the key elements acupuncture-induced analgesia. At brain level, Endogenous opioid peptides, limbic system play essential roles in mediating the analgesia. Conclusion: Acupuncture is an effective approach to pain management. There is good evidence in both experimental and clinical research that supports acupuncture efficacy in management of chronic pain through central nervous system. Acupuncture should be strongly used as a part of pain management plans. This work helps in improving our understanding of the scientific basis underlying acupuncture analgesia.

  2. 中原石油污染土壤原位微生物生态修复技术的应用%Application research of microbial and ecological remediation for oil contaminated soil in Central Plains

    Institute of Scientific and Technical Information of China (English)

    张胜; 陈立; 李政红; 张翠云; 殷密英; 马琳娜; 何泽; 孙振华; 张发旺

    2011-01-01

    The field remediation of the oil residue pollution in soil were carried out in Zhongyuan Oil Field, which using the optimistic techniques of in-situ microbial communities combining with the physical and chemistrial methods. The results showed that degradation rate can reach 99% as the oil content of 2 898.25 mg/kg in polluted soil after 99 d microbial and ecological remediation, which provide us the feasible technology and application of oil residue pollution remediation in soil at oilfields.%利用优化原位土著微生物菌群辅以物理和化学相结合的生态修复技术,进行了河南中原油田石油残留污染土壤的野外修复应用研究.修复结果显示,土壤中残留石油含量平均在2 898.25 mg/kg时,经过99 d微生物生态修复技术的实施,土壤中石油含量降解可达99%以上,为油田区土壤石油残留污染的修复提供了技术方法和推广应用的可行性研究.

  3. Application of ground-source heat pump with capillary mesh central air conditioning system in summer%毛细管网热泵集中空调系统夏季应用实例分析

    Institute of Scientific and Technical Information of China (English)

    张洋; 刘晓蕊; 郑英姿; 韩东太

    2011-01-01

    The system combines ground-source heat pump technology and capillary mesh radiation technology,taking ground-source heat pump unit as cold and heat source and capillary mesh as terminal device. Presents the application case of the system. Explains the effect of outdoor air system and gravity circulating air conditioning unit on desiccant and compares the measured parameters. Puts forward some problems needed special attention and treatment during construction and operation of the system.%该系统将地源热泵技术与毛细管网辐射技术相结合,以地源热泵机组为冷热源,末端采用毛细管网.介绍了该系统在夏季的应用实例,阐述了新风系统及重力循环空调柜联合除湿的效果,并将实测参数进行对比,提出了系统在施工及运行过程中需要注意的问题.

  4. Central Stars of Planetary Nebulae

    CERN Document Server

    Jones, David

    2016-01-01

    In this brief invited review, I will attempt to summarise some of the key areas of interest in the study of central stars of planetary nebulae which (probably) won't be covered by other speakers' proceedings. The main focus will, inevitably, be on the subject of multiplicity, with special emphasis on recent results regarding triple central star systems as well as wide binaries which avoid a common-envelope phase. Furthermore, in light of the upcoming release of Kepler's Campaign 11 data, I will discuss a few of the prospects from that data including the unique possibility to detect merger products.

  5. 7 CFR 319.56-25 - Papayas from Central America and Brazil.

    Science.gov (United States)

    2010-01-01

    ... 7 Agriculture 5 2010-01-01 2010-01-01 false Papayas from Central America and Brazil. 319.56-25... § 319.56-25 Papayas from Central America and Brazil. The Solo type of papaya may be imported into the... section and all other applicable provisions of this subpart. (a) The papayas were grown and packed...

  6. TEACHING ENGLISH IN SEVERAL CENTRAL AND EASTERN EUROPEAN COUNTRIES

    Directory of Open Access Journals (Sweden)

    Sim Monica Ariana

    2008-05-01

    Full Text Available The Central and Eastern European countries find themselves at present, following a period of transition in all domains, education included. One of the greatest challenges is providing sufficient foreign language education so as to meet the growing demand especially after along period of time when foreign languages were seriously and damagingly neglected. This paper is an attempt to briefly present the way English language is taught in several Central and Eastern European Countries as well as to underline the importance of this educational process and maybe to offer some applicable solutions to teaching English in Romania

  7. Systematic approaches to central nervous system myelin.

    Science.gov (United States)

    de Monasterio-Schrader, Patricia; Jahn, Olaf; Tenzer, Stefan; Wichert, Sven P; Patzig, Julia; Werner, Hauke B

    2012-09-01

    Rapid signal propagation along vertebrate axons is facilitated by their insulation with myelin, a plasma membrane specialization of glial cells. The recent application of 'omics' approaches to the myelinating cells of the central nervous system, oligodendrocytes, revealed their mRNA signatures, enhanced our understanding of how myelination is regulated, and established that the protein composition of myelin is much more complex than previously thought. This review provides a meta-analysis of the > 1,200 proteins thus far identified by mass spectrometry in biochemically purified central nervous system myelin. Contaminating proteins are surprisingly infrequent according to bioinformatic prediction of subcellular localization and comparison with the transcriptional profile of oligodendrocytes. The integration of datasets also allowed the subcategorization of the myelin proteome into functional groups comprising genes that are coregulated during oligodendroglial differentiation. An unexpectedly large number of myelin-related genes cause-when mutated in humans-hereditary diseases affecting the physiology of the white matter. Systematic approaches to oligodendrocytes and myelin thus provide valuable resources for the molecular dissection of developmental myelination, glia-axonal interactions, leukodystrophies, and demyelinating diseases.

  8. Central Libraries in Uncertain Times.

    Science.gov (United States)

    Kenney, Brian J.

    2001-01-01

    Discusses security and safety issues for public libraries, especially high-profile central facilities, in light of the September 11 terrorist attacks. Highlights include inspecting bags as patrons enter as well as exit; the need for security guidelines for any type of disaster or emergency; building design; and the importance of communication.…

  9. New Economy, Old Central Banks?

    NARCIS (Netherlands)

    Berk, Jan Marc

    2002-01-01

    Proponents of the so-called New Economy claim that it entails a structural change of the economy. Such a change, in turn, would require the central bank to rethink its monetary policy to the extent that traditional relationships between inf1ation and economic growth are no longer valid. But such a r

  10. Vulnerability in north- central Vietnam

    DEFF Research Database (Denmark)

    Casse, Thorkil; Milhøj, Anders; Nguyen, Thao Phuong

    2015-01-01

    This article examines changes in livelihood strategies in response to flooding. It does so on the basis of a household survey which was undertaken in three provinces in north central Vietnam. All households in the survey were regularly affected by flooding, but only poor households experience...

  11. Water Governance in Central Asia

    NARCIS (Netherlands)

    Djanibekov, Nodir; Assche, Van Kristof; Valentinov, Vladislav

    2016-01-01

    We develop a social systems theory perspective on Central Asian post-Socialist transition, placing particular emphasis on the coordination problems in transboundary water governance. The extensive Soviet water-energy infrastructure around the Amudarya and Syrdarya rivers required coordination, bu

  12. The Centrality of Ethical Leadership

    Science.gov (United States)

    Ehrich, Lisa C.; Harris, Jessica; Klenowski, Val; Smeed, Judy; Spina, Nerida

    2015-01-01

    Purpose: The central argument in this paper is that ethical school leadership is imperative in a context of increasing performance-driven accountability. The purpose of this paper is to focus on school principals' perceptions of how they understand ethical leadership and how they lead the ethical use of data. Design/Methodology/Approach: This…

  13. Learning and the central bank

    OpenAIRE

    Charles T. Carlstrom; Timothy S. Fuerst

    2001-01-01

    It is well known that sunspot equilibria may arise under an interest-rate operating procedure in which the central bank varies the nominal rate with movements in future inflation (a forward-looking Taylor rule). This paper demonstrates that these sunspot equilibria may be learnable in the sense of E-stability.

  14. The MEANING multilingual central repository

    NARCIS (Netherlands)

    Atserias, J.; Villarejo, L.; Rigau, G.; Agirre, E.; Carroll, J.; Magnini, B.; Vossen, P.

    2004-01-01

    This paper describes the first version of the Multilingual Central Repository, a lexical knowledge base developed in the framework of the MEANING project. Currently the MCR integrates into the EuroWordNet framework five local wordnets (including four versions of the English WordNet from Princeton),

  15. Copycats of the Central Himalayas

    NARCIS (Netherlands)

    P.A. Arora (Payal)

    2009-01-01

    textabstractThis case study highlights practices of a rarely documented group of neo-users of the Internet or newbies from Central Himalayas, serving as a catalyst for delving deeply into the act of ‘plagiarism’ in online learning By looking at such ‘learning’ practices away from schools, namely at

  16. Central configurations, periodic orbits, and Hamiltonian systems

    CERN Document Server

    Llibre, Jaume; Simó, Carles

    2015-01-01

    The notes of this book originate from three series of lectures given at the Centre de Recerca Matemàtica (CRM) in Barcelona. The first one is dedicated to the study of periodic solutions of autonomous differential systems in Rn via the Averaging Theory and was delivered by Jaume Llibre. The second one, given by Richard Moeckel, focusses on methods for studying Central Configurations. The last one, by Carles Simó, describes the main mechanisms leading to a fairly global description of the dynamics in conservative systems. The book is directed towards graduate students and researchers interested in dynamical systems, in particular in the conservative case, and aims at facilitating the understanding of dynamics of specific models. The results presented and the tools introduced in this book include a large range of applications.

  17. Towards Quantum Transport for Central Nuclear Reactions

    CERN Document Server

    Danielewicz, Pawel; Barker, Brent

    2016-01-01

    Nonequilibrium Green's functions represent a promising tool for describing central nuclear reactions. Even at the single-particle level, though, the Green's functions contain more information that computers may handle in the foreseeable future. In this study, we explore slab collisions in one dimension, first in the mean field approximation and demonstrate that only function elements close to the diagonal in arguments are relevant, in practice, for the reaction calculations. This bodes well for the application of the Green's functions to the reactions. Moreover we demonstrate that an initial state for a reaction calculation may be generated through adiabatic transformation of interactions. Finally, we report on our progress in incorporating correlations into the dynamic calculations.

  18. Central Facilities Area Sewage Lagoon Evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Giesbrecht, Alan [Idaho National Lab. (INL), Idaho Falls, ID (United States)

    2015-03-01

    The Central Facilities Area (CFA) located in Butte County, Idaho at Idaho National Laboratory (INL) has an existing wastewater system to collect and treat sanitary wastewater and non contact cooling water from the facility. The existing treatment facility consists of three cells: Cell 1 has a surface area of 1.7 acres, Cell 2 has a surface area of 10.3 acres, and Cell 3 has a surface area of 0.5 acres. If flows exceed the evaporative capacity of the cells, wastewater is discharged to a 73.5 acre land application site that utilizes a center pivot irrigation sprinkler system. The purpose of this current study is to update the analysis and conclusions of the December 2013 study. In this current study, the new seepage rate and influent flow rate data have been used to update the calculations, model, and analysis.

  19. Reduced central blood volume in cirrhosis

    DEFF Research Database (Denmark)

    Henriksen, Jens Henrik; Bendtsen, Flemming; Sørensen, T I

    1989-01-01

    for measuring the central blood volume. We have developed a method that enables us to determine directly the central blood volume, i.e., the blood volume in the heart cavities, lungs, and central arterial tree. In 60 patients with cirrhosis and 16 control subjects the central blood volume was assessed according...

  20. 27 CFR 9.75 - Central Coast.

    Science.gov (United States)

    2010-04-01

    ... 27 Alcohol, Tobacco Products and Firearms 1 2010-04-01 2010-04-01 false Central Coast. 9.75... Central Coast. (a) Name. The name of the viticultural area described in this section is “Central Coast.” (b) Approved maps. The approved maps for determining the boundary of the Central Coast...

  1. 《中央银行与金融监管》课程的教学改革探索--以应用型本科院校为例%The Teaching Reform of the Course of“Central Bank and Financial Regulation”---A Case Study of Application Oriented Universities

    Institute of Scientific and Technical Information of China (English)

    秦菊香; 张晶

    2016-01-01

    Central bank and financial regulation is the core curriculum of finance and economics uni-versities,for cultivating student’s knowledge about financial system and financial thinking,which also play a pivotal role in professional talent training goal.In the application oriented institutes,courses should comply with financial application talents cultivation to carry out the teaching reform.In the ar-rangement of the teaching contents,teaching methods and assessment methods,we should consider the teaching theoretical knowledge and methods,at the same time and we should also pay more attention to the de-velopment of students’ability of knowledge application and operating ability.%《中央银行与金融监管》是财经类高校金融学专业的核心课程,对于构建学生金融知识体系和培养学生金融思维,实现专业人才培养目标具有举足轻重的作用。在应用型本科院校,课程应紧紧围绕实现应用型金融人才培养目标进行教学改革,在教学内容的安排、教学方法与手段的使用、考核方式的选择等方面,既要考虑系统传授理论知识和方法的需要,也要考虑培养学生的知识应用能力和动手操作能力的需要。

  2. Application of mouse nervous growth factor on hand-foot-mouth disease combined with central nervous system damage%鼠神经生长因子治疗手足口病合并中枢神经系统损害的研究

    Institute of Scientific and Technical Information of China (English)

    宋蕊; 冯亮; 李兴旺; 徐艳丽; 卢联合; 蒋荣猛; 陈志海

    2011-01-01

    Objective To investigate the application of mouse nervous growth factor (mNGF) on patients with hand-foot-and-mouth disease (HFMD) combined with central nervous system damage. Methods Clinical data of 48 patients with HFMD combined with central nervous system damage, admitted to our hospital and received treatment of mNGF from May 2008 to September 2010, were analyzed retrospectively. Results Children under 5 years old, especially between 1-3 years old, were the high-risk group of having HFMD combined with central nervous system damage. The average time of appearing of acute flaccid paralysis (AFP) and recovering of muscle strength were (7.1±3.6) d and (17.5±6.0) d, respectively. A total of 31 patients (64.58%) appeared vomiting, with its average times of appearance and disappearance as (4.29±3.10) d and (5.74±2.90) d, respectively. A total of 33 patients (68.75%) tended to appear panic symptoms, which appeared on (2.67±1.76) d and disappeared on (7.80± 2.76) d averagely. Laboratory test showed number of white blood cells and CK values were elevated of certain degree, and cerebrospinal fluid pressure and protein expression level were increased to varying degrees. MRI showed that bulbus medulla was the most likely to be involved, followed by brain stem and other parts. Conclusion Application of mNGF on patients with HFMD combined with central system damage may help to improve the neurologic symptoms and prognosis.%目的 探讨鼠神经生长因子在手足口病合并中枢神经系统损害患者治疗中的应用.方法 收集北京地坛医院自2008年5月至2010年9月收治的手足口病合并中枢神经系统损害并使用鼠神经生长因子治疗的48例患者的临床资料,采用回顾性分析方法总结其特点.结果 5岁以下尤其是1~3岁儿童是手足口病合并中枢神经系统损害高危人群.患者急性弛缓性麻痹症状出现时间平均在病程第(7.1±3.6)天,肌力恢复平均在第(17.5±6.0)天;呕吐症状出现

  3. Comparison of Two Kinds of Application of Puncture Approach Ways of Central Vein Catheterization in Critically Ill Patients%两种穿刺入路方式中心静脉置管术在危重症抢救中的应用比较

    Institute of Scientific and Technical Information of China (English)

    谢德东; 周莉娟; 陈力; 戴领

    2014-01-01

    Objective To compare two kinds of puncture approach ways of central vein catheterization in the critically ill rescue application, in the way of central vein to seek for optimal rescue critically ill patients. Methods A retrospective analysis from 2008 March to 2013 year in March 900 cases of critically ill patients in our center of central venous catheterization patients clinical data, which take the internal jugular vein puncture approach in 420 cases, puncture of subclavian vein approach in 480 cases, based on the two kinds of puncture approach ways of central vein catheterization occurred in quick puncture success rate and puncture related complications rate analysis. Results The success rate of puncture of internal jugular vein puncture ap-proach: 336 cases (80% ); puncture of subclavian vein approach in 456 cases (95% ); the incidence rate of puncture related complications: internal jugular vein puncture approach in 69 cases (16. 4% ), puncture of subclavian vein in 20 cases (4. 2% ). Conclusion In critically ill patients subclavian vein puncture approach ways of central vein catheterization rate is better than that of internal jugular vein puncture approach in fast puncture success rate and puncture related complications.%目的:比较两种穿刺入路方式中心静脉置管术在危重症抢救中的应用,寻求适用于危重症患者抢救中最优的中心静脉置管入路方式。方法回顾性分析2008年3月至2013年3月我中心900例危重抢救患者中心静脉置管术临床资料,其中采取颈内静脉穿刺入路方式420例,锁骨下静脉穿刺入路方式480例,通过对两种穿刺入路方式中心静脉置管术在快速穿刺成功率及穿刺相关并发症发生率方面进行分析比较。结果一针穿刺成功率:颈内静脉穿刺入路方式336例(80%);锁骨下静脉穿刺入路方式456例(95%);穿刺相关并发症发生率:颈内静脉穿刺入路方式69例(16.4%),锁

  4. Analysis of the Application Value of Ultrasonography in the Diagnosis of Fetal Malformation of the Central Nervous System%超声检查在胎儿中枢神经系统畸形诊断中的应用价值探析

    Institute of Scientific and Technical Information of China (English)

    花秋菊; 关云萍; 项宇识

    2015-01-01

    目的:针对超声检查在胎儿中枢神经系统畸形诊断中的应用价值进行探讨分析。方法选择于2012年12月—2013年12月在该院进行产前超声诊断的70例单胎孕妇为研究对象,所有孕妇的胎儿经分娩后随访和引产后尸检证实为中枢神经系统畸形,分析超声表现和超声检查的临床符合率。结果所有胎儿中,引产68例,继续妊娠后生产2例。经病理检查证实该组胎儿严重小脑畸形1例,3例脊柱裂,11例脑膜脑膨出和脑膜膨出,23例为脑积水,31例为无脑畸形。通过产前超声检查诊断,胎儿中枢神经系统畸形包括:1例蛛网膜囊肿,3例脊柱裂,11例脑膜脑膨出和脑膜膨出,23例为脑积水,32例为无脑畸形。超声检查与病理检查结果的临床符合率98.9%,误诊率为1.1%。结论超声检查在胎儿中枢神经系统畸形诊断中的应用具有较高的诊断率,并且操作简便,无创伤,可以作为产前排除胎儿中枢神经系统畸形的重要方法。%Objective To explore and analyze the application value of ultrasonography in the diagnosis of fetal malformation of the central nervous system. Methods 70 singleton pregnant women underwent prenatal ultrasound diagnosis in our hospital from De-cember 2012 to December 2013 were selected as the subjects. All the fetuses were confirmed as malformation of the central ner-vous system by follow-up after delivery or autopsy after induced labour. And the clinical coincidence rate of ultrasonic manifesta-tions and ultrasonic examination was analyzed. Results Of all the fetuses, there were 68 cases of induced abortion, 2 cases of de-livery after continued pregnancy. It was confirmed by the pathological examination that there was 1 case with cerebellar malforma-tion, 3 cases with spina bifida, 11 cases with encephalomeningocele and meningiocele, 23 cases with hydrocephalus, 31 cases with anencephaly. The prenatal ultrasonography showed

  5. Application of Neuronavigation and Electrophysiological Monitoring in the Resection of Lesions near the Central Sulcus%神经导航和电生理监测在中央沟附近病变切除术中的应用

    Institute of Scientific and Technical Information of China (English)

    陈汉民; 王文鑫; 廖圣芳

    2014-01-01

    Objective]To explore the application of neuronavigation and electrophysiological monitoring in the resection of lesions near the central sulcus .[Methods]A total of 14 patients with lesions near the central sulcus in our hospital underwent microsurgical procedures assisted with neuronavigation and electrophysiological monito‐ring .Clinical efficacy was observed .[Results]In the group ,9 patients underwent total resection and 5 patients un‐derwent partial resection .After operation ,contralateral limb muscle strength impairment occurred in 2 patients af‐ter operation ,and hemiplegia occurred in 1 patient ,and limb muscle strength impairment was aggravated in 2 pa‐tients .The 3 patients with limb movement disorder got better about one month after operation .[Conclusion]The combination of intraoperative neuronavigation and electrophysiological monitoring is of great clinical practical value in the resection of lesions near the central sulcus .%目的 探讨神经导航和电生理监测在中央沟附近病变切除术中的应用。方法 本院收治的14例中央沟附近病变患者,在神经导航和电生理监测下行显微手术切除病变,观察其临床疗效。结果 本组中病变全切除9例,大部分切除5例。术后出现对侧肢体肌力减退2例,偏瘫1例,术前肢体肌力减退加重2例,3例肢体运动障碍者术后1个月左右好转。结论 联合应用神经导航和电生理监测技术在中央沟附近病变切除术中具有较大的临床实用价值。

  6. 新疆某电厂办公区半集中式蒸发冷却空调系统的工程应用分析%In A Power Plant in Xinjiang Office Semi-central Evaporative Air-conditioning System Application Analysis

    Institute of Scientific and Technical Information of China (English)

    王伟; 黄翔; 孙铁柱; 吴生; 于优城; 唐永戬; 杨晓弟

    2012-01-01

    介绍了半集中式蒸发冷却空调系统的设计过程,对应用在新疆某电厂办公区的半集中式蒸发冷却空调系统进行详细的测试分析.测试结果表明:三级蒸发冷却新风机组将室外干球温度为35℃,湿球温度为19.8℃的空气,处理至干球温度为15℃低温空气送入室内.蒸发冷却高温冷水机组制取干球温度为17℃的冷水,完全满足干式风机盘管的要求.整个半集中式蒸发冷却串联系统中,风机盘管回水在高温表冷器中可以将室外空气的温度降低7℃以上,形成了冷量的多重利用.同时希望通过这样的实例设计过程分析为相关的设计人员提供一定的参考.%The design process of semi-central evaporative air conditioning system was briefly introduced, the application of a certain power plant in xinjiang office semi-central evaporative air conditioning system for detailed analysis of the test. Test results show that; three new air handling units to evaporative cooling outdoor dry bulb temperature of 35℃ , wet bulb temperature of 19. 8℃, air treatment to dry bulb temperature is 15℃ low temperature air into the room. Evaporative cooling high-temperature water chiller system to take dry-bulb temperature of 17℃ cold water, fully meet the requirements of dry-type fan coil. Evaporative cooling throughout the series semi-centralized system, fan coil return water at high temperatures can be cooler outdoor air temperature 7℃ lower than the formation of a cooling capacity of multiple use. Also hope that through this analysis of the relevant instance of the design process designers to provide a reference.

  7. 全自动片剂摆药机在我院中心药房的应用%Application of Full-Automatic Tablet Dispensing Machine in the Central Pharmacy of Our Hospital

    Institute of Scientific and Technical Information of China (English)

    訾梅; 古艳婷

    2015-01-01

    OBJECTIVE:To provide references for rational application of full-automatic tablet dispensing machine in the inpa-tient pharmacy of the hospital. METHODS:According to the work flow and use of the machine,the errors and problems arising from the use thereof by our hospital were summarized and analyzed,and corresponding improvement measures and solutions were put forward. RESULTS & CONCLUSIONS:Common errors in the use of full-automatic tablet dispensing machine included errors for the machine(including in-box drug shortage warnings accounting for 58.61% and abnormal responses to the quantity of in-box drugs accounting for 36.96%),errors caused by human factors(including errors of inputting doctor’s order and errors of pharma-cist’s adding drugs)and errors of material installation and operation. The solutions put forward are as follows as adjusting the tilt angle of the outlet mouth and controlling the quantity of the drugs added to the box to reduce the errors for the machine;two phar-macists’checking doctor’s order in the hospital information system in advance to reduce the errors caused by human factors;carry-ing out operation training for operators to reduce the errors of material installation;designating special personnel to maintain the ma-chine,etc.%目的:为医院住院药房合理应用全自动片剂摆药机提供参考。方法:根据全自动片剂摆药机的工作流程和使用情况,总结分析我院在其使用中发生的差错及问题,并提出改进措施和解决方法。结果与结论:使用全自动片剂摆药机的常见差错包括自动摆药机发生的差错(其中药盒缺药报警占58.61%,药盒内数量反应错误占36.96%)、人为因素产生的差错(包括医嘱录入错误和药师加药错误)以及耗材安装操作差错。提出的解决方法包括调整出药口的倾斜角度、控制贮药盒内药品添加的数量以减少自动摆药机发生的差错;药师提前审核医院信

  8. Central venous line complications and tip detection

    OpenAIRE

    Ameneh Rezaee Gheshlaghi; Hamid Zamani Moghadam Dolu; Elham Pishbin; Maryam Salehi

    2015-01-01

    Central venous line is one of a creative instrument that saves human’s life in critical medical situation. Central venous line access is frequently involved in the disease management. It is used for rapid fluid therapy, transvenous pacemakers, infusion of some medications, hemodialysis or plasmapheresis and etc. Most of the emergency departments have some staffs that are trained for central venous line insertion but related complications occur during central venous line placement.Central veno...

  9. Is Central Asia really exsiccating?

    Science.gov (United States)

    Aizen, V. B.; Aizen, E. M.; Surazakov, A. B.

    2008-12-01

    At the end of 20th and the beginning of 21st century central Asia oases suffered from serious drought caused lack of water for agriculture, economy growth and population increase. However, people of this region always experienced lack of water for irrigation and fought a war over the rights to control river streams. The drying up of central Asian rivers is not a new phenomenon according to the ancient manuscripts. Thus, lets see about what has happened with the past century climate and water resources of central Asia using the long-term observational data. We analyzed data from more than 200 meteorological stations and stream gauges over the central Asia in elevation range from 25 m. b.s.l. to 4,000 m. a.s.l. to understand the last 100 years variability in climate and water resources, examining changes in the extreme and mean monthly air temperatures, precipitation and river runoff. The evaluation of seasonal snow and glacier's covered areas between 1970th and 2007th in central Asia derived from AVHRR, MODIS, Hexagon KH-9, Landsat ETM and ASTER data exhibit 15% reduction of the seasonal snow covered area and 10.1% of the glacier area. It has been found that during last twenty years the duration of snowmelt, from the date of maximum snow cover to date of its disappearance, reduced by 30 days and in 2007 was equal to 138 days in the central Asian mountains. The decrease of seasonal snow cover is not a linear process. The further decrease may be accelerated due to increase of rainfall instead of snowfall in early spring months at high elevations, and consequently a lesser heat expenditure for the snowmelt. The growth in summer air temperatures, especially observable since the 1970th, accompanied by increase of evapotranspiration and precipitation, notably in summer and autumn, and at high elevations over 3,000 m, and at the western peripheral mountain ridges. Average difference in the means of annual air temperatures for the two thirty-year periods before and after

  10. Composite Centrality: A Natural Scale for Complex Evolving Networks

    CERN Document Server

    Joseph, Andreas

    2012-01-01

    We derive a composite centrality measure for general weighted and directed complex networks, based on measure standardisation and invariant statistical inheritance. Different inheritance schemes generate different intermediate abstract measures providing additional information, while the overall composite centrality measure tends to the standard log-normal distribution. This offers a unified scale to measure node and edge centralities for complex evolving networks inside a uniform framework. Considering the two real-world cases of the world trade web and the world migration web, both during a time span of 40 years, we propose a standard framework and demonstrate its remarkable normative power and accuracy. We demonstrate the applicability of the proposed framework to large and arbitrary complex systems by the means of numerical simulations.

  11. The Central Valley Hydrologic Model

    Science.gov (United States)

    Faunt, C.; Belitz, K.; Hanson, R. T.

    2009-12-01

    Historically, California’s Central Valley has been one of the most productive agricultural regions in the world. The Central Valley also is rapidly becoming an important area for California’s expanding urban population. In response to this competition for water, a number of water-related issues have gained prominence: conjunctive use, artificial recharge, hydrologic implications of land-use change, subsidence, and effects of climate variability. To provide information to stakeholders addressing these issues, the USGS made a detailed assessment of the Central Valley aquifer system that includes the present status of water resources and how these resources have changed over time. The principal product of this assessment is a tool, referred to as the Central Valley Hydrologic Model (CVHM), that simulates surface-water flows, groundwater flows, and land subsidence in response to stresses from human uses and from climate variability throughout the entire Central Valley. The CVHM utilizes MODFLOW combined with a new tool called “Farm Process” to simulate groundwater and surface-water flow, irrigated agriculture, land subsidence, and other key processes in the Central Valley on a monthly basis. This model was discretized horizontally into 20,000 1-mi2 cells and vertically into 10 layers ranging in thickness from 50 feet at the land surface to 750 feet at depth. A texture model constructed by using data from more than 8,500 drillers’ logs was used to estimate hydraulic properties. Unmetered pumpage and surface-water deliveries for 21 water-balance regions were simulated with the Farm Process. Model results indicate that human activities, predominately surface-water deliveries and groundwater pumping for irrigated agriculture, have dramatically influenced the hydrology of the Central Valley. These human activities have increased flow though the aquifer system by about a factor of six compared to pre-development conditions. The simulated hydrology reflects spatial

  12. Centrality in Interconnected Multilayer Networks

    CERN Document Server

    De Domenico, Manlio; Omodei, Elisa; Gómez, Sergio; Arenas, Alex

    2013-01-01

    Real-world complex systems exhibit multiple levels of relationships. In many cases, they require to be modeled by interconnected multilayer networks, characterizing interactions on several levels simultaneously. It is of crucial importance in many fields, from economics to biology, from urban planning to social sciences, to identify the most (or the less) influent nodes in a network. However, defining the centrality of actors in an interconnected structure is not trivial. In this paper, we capitalize on the tensorial formalism, recently proposed to characterize and investigate this kind of complex topologies, to show how several centrality measures -- well-known in the case of standard ("monoplex") networks -- can be extended naturally to the realm of interconnected multiplexes. We consider diagnostics widely used in different fields, e.g., computer science, biology, communication and social sciences, to cite only some of them. We show, both theoretically and numerically, that using the weighted monoplex obta...

  13. Centralized versus Decentralized Infrastructure Networks

    CERN Document Server

    Hines, Paul D H; Schläpfer, Markus

    2015-01-01

    While many large infrastructure networks, such as power, water, and natural gas systems, have similar physical properties governing flows, these systems tend to have distinctly different sizes and topological structures. This paper seeks to understand how these different size-scales and topological features can emerge from relatively simple design principles. Specifically, we seek to describe the conditions under which it is optimal to build decentralized network infrastructures, such as a microgrid, rather than centralized ones, such as a large high-voltage power system. While our method is simple it is useful in explaining why sometimes, but not always, it is economical to build large, interconnected networks and in other cases it is preferable to use smaller, distributed systems. The results indicate that there is not a single set of infrastructure cost conditions under which optimally-designed networks will have highly centralized architectures. Instead, as costs increase we find that average network size...

  14. A centralized audio presentation manager

    Energy Technology Data Exchange (ETDEWEB)

    Papp, A.L. III; Blattner, M.M.

    1994-05-16

    The centralized audio presentation manager addresses the problems which occur when multiple programs running simultaneously attempt to use the audio output of a computer system. Time dependence of sound means that certain auditory messages must be scheduled simultaneously, which can lead to perceptual problems due to psychoacoustic phenomena. Furthermore, the combination of speech and nonspeech audio is examined; each presents its own problems of perceptibility in an acoustic environment composed of multiple auditory streams. The centralized audio presentation manager receives abstract parameterized message requests from the currently running programs, and attempts to create and present a sonic representation in the most perceptible manner through the use of a theoretically and empirically designed rule set.

  15. The CDF Central Analysis Farm

    Energy Technology Data Exchange (ETDEWEB)

    Kim, T.H.; /MIT; Neubauer, M.; /UC, San Diego; Sfiligoi, I.; /Frascati; Weems, L.; /Fermilab; Wurthwein, F.; /UC, San Diego

    2004-01-01

    With Run II of the Fermilab Tevatron well underway, many computing challenges inherent to analyzing large volumes of data produced in particle physics research need to be met. We present the computing model within CDF designed to address the physics needs of the collaboration. Particular emphasis is placed on current development of a large O(1000) processor PC cluster at Fermilab serving as the Central Analysis Farm for CDF. Future plans leading toward distributed computing and GRID within CDF are also discussed.

  16. Central Nucleon-Nucleon Potential

    Science.gov (United States)

    Robilotta, M. R.

    2001-12-01

    The outer region of the NN interactions is dominated by the one pion exchange potential (OPEP), followed by the two-pion exchange potential (TPEP). Chiral calculations of the TPEP have been performed using either heavy baryon1 (HB) or relativistic2 perturbation theories. We compare the predictions from these two approaches for the dominant central interaction and show that they fail to agree by 25% ...

  17. Celtic Sites of Central Iberia

    Science.gov (United States)

    Pérez Gutiérrez, Manuel

    This chapter concerns the astronomy practiced by Celtic peoples in some parts of central Iberia, specifically the Vetton and Celtiberian peoples, inhabitants of the so-called Late Iron Age. The construction of some elements of religion or worship was perfectly determined by geometry, topography, and especially astronomy, because their spatial orientation occurs in locations of great interest for maintaining the local calendar. The maintenance of this calendar was probably the primary objective of some of the elements studied.

  18. Information from the central stores

    CERN Multimedia

    GS Department

    2010-01-01

    All items sold in the CERN shop (Bldg. 33) are now available in the central stores (Bldg. 73) and can be purchased on-line via EDH “Material Request” or at the “Emergency Desk” of the stores on the ground floor of Bldg. 73. These items are visible in the CERN catalogue under the “SCEM” codes beginning with 92. Department of General Infrastructure Services (GS) GS-SEM Group

  19. Central charges in regular mechanics

    CERN Document Server

    Cabo-Montes de Oca, Alejandro; Villanueva, V M

    1997-01-01

    We consider the algebra associated to a group of transformations which are symmetries of a regular mechanical system (i.e. system free of constraints). For time dependent coordinate transformations we show that a central extension may appear at the classical level which is coordinate and momentum independent. A cochain formalism naturally arises in the argument and extends the usual configuration space cochain concepts to phase space.

  20. Evaluation of line focus solar central power systems. Volume I. Executive summary

    Energy Technology Data Exchange (ETDEWEB)

    1980-03-15

    An evaluation was completed to ascertain the applicability of line focus technologies to electrical power applications and to compare their performance and cost potential with point focus central receiver power systems. It was concluded that although the high temperature line focus (SRI) and fixed mirror line focus (GA) concepts duplicate the heat source characteristics and power conversion technology of the central receiver concepts these configurations do not offer a sufficient improvement in cost to warrant full scale development. The systems are, however, less complex than their point focus counterpart and should the central receiver system development falter they provide reasonable technology alternatives. This volume is an executive summary. (WHK)