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Sample records for apos apicectomia tratamento

  1. Tratamento da leishmaniose tegumentar americana pelo niridazol

    Directory of Open Access Journals (Sweden)

    Miroslau Constante Baranski

    1970-08-01

    Full Text Available Foi empregue o niridazol um derivado do nitrotiazol, em doze pacientes com leishmaniose tegumentar americana. Em todos êles, o diagnóstico clínico da doença foi confirmado pela biópsia das lesões e em oito dêles também pela positividade da intradetermorreação de Montenegro. Oito pacientes tinham lesões mucosas metastáticas em atividade e lesões cutâneas iniciais cicatrizadas há tempo mais ou menos longo. Dois apresentavam concomitância de lesões cutâneas e mucosas em atividade, e dois tinham lesões cutâneas exclusivas. A duração da doença variou de 2 meses a 32 anos. A posologia diária do niridazol foi uniformememente de 25 mg/kg de pêso corpóreo. O medicamento foi administrado por via oral, em duas tomadas diárias, sempre com o doente internado em hospital. Quando a tolerância o permitia, o paciente recebia cinco séries de tratamento de 10 dias de duração cada, intercaladas por períodos áe suspensão da droga de 10 dias entre uma série e outra. Isso foi possível em 10 dos 12 pacientes. O tratamento foi bem tolerado em 5 doentes e de tolerância regular em 4. Mal tolerado em um paciente pela ocorrência de alucinações e excitação mental e interrompido pela péssima tolerância em dois doentes devido ao aparecimento de convulsões generalizadas com perda da consciência. O tratamento acompanhou-se de grande incidência, de efeitos colaterais. A ocorrência de para-efeitos mais intensos não foi devida às más condições hepáticas. Provas de função hepática. hemogramas, estudos bioquímicos do sangue e exames de urina, realizados antes, durante e após o tratamento, não revelaram alterações significativas. Biópsias hepáticas por punção com agulha em dez doentes, prévias e posteriores ao tratamento, não detectaram lesões hepáticas que pudessem ser atribuídas à medicação. O seguimento dos doentes prolongou-se pelo prazo de dois a 36 meses apos o tratamento. Alterações eletrocardiogr

  2. Magnetic nanoparticles for cancer therapy; Nanoparticulas magneticas para o tratamento do cancer

    Energy Technology Data Exchange (ETDEWEB)

    Bakuzis, Andris F. [Universidade Federal de Goias (UFG), Goiania, GO (Brazil). Instituto de Fisica

    2014-07-01

    Full text: Magnetic nanoparticles have been used in several biomedical applications, spanning from cell separation, early diagnosis of metastasis to even the treatment of cancer via magnetic hyperthermia (MH). This last technique consists in the increase of temperature of nanoparticles when their magnetic moments interact with a magnetic alternating field. This effect has been suggested as an innovative therapy to cancer treatment, due to the delivery of heat or therapeutic agents, such as drugs, genes, and others. In addition, several clinical studies has demonstrated synergetic effects between hyperthermia and radiotherapy [1]. This indicates a great therapeutic potential for this noninvasive and targeted technique. In this talk we will discuss results from the literature and from our own group in the treatment of cancer via magnetic hyperthermia. Several types of magnetic nanoparticles suggested for this application will be discussed, as well as the historical evolution of this procedure, which although suggested in the late 50' only recently was approved in Europe for treatment of humans with brain tumors. (author) [Portuguese] Full text: Nanoparticulas magneticas tem sido utilizadas em diversas aplicacoes biomedicas, desde a separacao de celulas, marcacao de celulas-tronco, diagnostico precoce de metastases ao tratamento do cancer via hipertermia magnetica (HM). Esta ultima tecnica consiste no aumento da temperatura de nanoparticulas quando seus momentos magneticos interagem de forma adequada com um campo magnetico alternado. Este efeito tem sido idealizado como uma nova terapia para o tratamento do cancro, seja via entrega seletiva de calor ou mesmo pela liberacao de farmacos, genes ou outros agentes terapeuticos por meio desta acao externa. Adicionalmente, diversos estudos clinicos tem demonstrado efeitos sinergicos entre a hipertermia e tecnicas tradicionais de tratamento oncologico, como quimioterapia e radioterapia. Isto indica um forte potencial

  3. Adesão ao tratamento da ambliopia

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    Arakaki Mara Regina

    2004-01-01

    Full Text Available OBJETIVO: Avaliar a influência da adesão no resultado do tratamento da ambliopia. MÉTODOS: Foi feito estudo retrospectivo avaliando a resposta ao tratamento da ambliopia em 151 crianças portadoras de ambliopia, tratadas com esquema de oclusão diária, com o número de dias variando de acordo com a idade da criança. Os pacientes foram separados em dois grupos que diferiam entre si pela adesão ou não ao tratamento. RESULTADOS: Observou-se que o tratamento teve melhores resultados nas crianças de 4 a 7 anos e que aderiram ao tratamento; as crianças que aderiram ao tratamento necessitaram de tempo menor de permanência em tratamento. Mesmo crianças com idade superior a 7 anos tiveram resultados positivos com a oclusão. CONCLUSÃO:O tratamento oclusivo é um meio terapêutico eficiente desde que haja a cooperação do paciente.

  4. CONTINUIDADES E DESCONTINUIDADES DO TRATAMENTO MORAL EM MODELOS DE TRATAMENTO PARA TOXICÕMANOS

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    Taís Bleicher

    2012-01-01

    Full Text Available Ao analisar aspectos do evoluir do tratamento médico voltado à loucura na França, com ênfase na inovação pineliana do século XIX, o tratamento moral, e os modelos que surgiram em oposição ou em continuidade com este (as Colônias Agrícolas, que se opunham ao ambiente dos hospitais eas comunidades terapêuticas, com fins de ressocialização, objetiva-se perceber em quê estes modelos, anteriormente aplicado aos loucos, estão presentes nos atuais tratamentos para toxicômanos, tanto em Fazendas de Recuperação, como em grupos de ajudaque seguem a Filosofia dos Doze Passos e que não adotam o sistema de internação. A partir da teoria psicanalítica(com ênfase nos conceitos de narcisismo, narcisismo secundário, ideal de eu e pulsãoquestionaremos estas formas de tratamento (especialmente no que diz respeito ao recurso à religião, a infantilização dos pacientes, o julgamento perpétuo, o lugar dado aos relacionamentos, em nomede uma possibilidade de existência criativa e autônoma por parte do toxicômano.

  5. Adesão ao tratamento da ambliopia

    OpenAIRE

    Arakaki,Mara Regina; Schellini,Silvana Artioli; Heimbeck,Felipe Jorge; Furuya,Margareth Tiemi; Padovani,Carlos Roberto

    2004-01-01

    OBJETIVO: Avaliar a influência da adesão no resultado do tratamento da ambliopia. MÉTODOS: Foi feito estudo retrospectivo avaliando a resposta ao tratamento da ambliopia em 151 crianças portadoras de ambliopia, tratadas com esquema de oclusão diária, com o número de dias variando de acordo com a idade da criança. Os pacientes foram separados em dois grupos que diferiam entre si pela adesão ou não ao tratamento. RESULTADOS: Observou-se que o tratamento teve melhores resultados nas crianças de ...

  6. Motivacao para o tratamento. Dados psicometricos da escala SOCRATES 8D e estrategias psicoterapeuticas para motivar para o tratamento

    OpenAIRE

    Janeiro, Luís; Faísca, Luís

    2008-01-01

    A motivação para o tratamento é considerada um factor fundamental para o processo de mudança e tratamento do toxicodependente. Prochaska, Diclemente, e Norcross (1992) consideram que a motivação que o sujeito possui no início do tratamento determina directamente os resultados alcançados no mesmo. Diclemente, Bellino, e Neavins (1999) acrescentam, ainda, que a estreita relação entre os resultados obtidos no tratamento e a motivação aquando do seu início pode ser medida pela formação precoce de...

  7. O psicanalista no tratamento da dor

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    Sueli Pinto Minatti

    2012-12-01

    Full Text Available A dor se manifesta como mal-estar do corpo e no corpo, e tende a ser encaminhada para tratamento médico. O objetivo deste trabalho é analisar a queixa dolorosa do ponto de vista do tratamento psicanalítico, retomando algumas acepções relacionadas ao tratamento da dor, encontradas na obra de Freud. Partimos da experiência no trabalho em hospital pediátrico, utilizando a análise do atendimento de pacientes com queixas de dor para definir e situar a dor no campo da psicanálise, e distingui-la do campo da medicina. No texto, pode-se acompanhar a dor como signo de sofrimento e diversas formas de abordá-la tanto pelo sujeito que a porta quanto pelas instituições que propõem seu cuidado.

  8. A new Job's tear cultivar ''Hatohikari''

    International Nuclear Information System (INIS)

    Ishida, M.; Chiba, I.; Kato, M.; Okuyama, Y.; Sugawara, S.; Tanosaki, S.; Shindo, K.; Ishikura, N.; Seki, K.; Endo, T.; Shibata, M.

    1997-01-01

    A new Job's tear cultivar ''Hatohikari'', developed at the Tohoku National Agricultural Experiment Station, Morioka, Japan was registered as Norin No.2 Job's tear and released by Japan's Ministry of Agriculture, Forestry and Fisheries in 1995. ''Hatohikari'' is a progeny from a gamma-ray radiated mutant of ''Okayama-zairai'' in 1980. ''Okayama-zairai'' shows high yield and good quality. However, its demerits are late maturity and long plant height. The major agronomic characteristics of the new cultivar ''Hatohikari'' are as follows: The maturity is earlier than that of ''Okayama0zairai'', yielding ability is 38% higher than that of ''Okayama-zairai , the plant height is 30 cm shorter than that of ''Okayama-zairai'' and it is suitable for combine harvest. ''Hatohikari'' has large seeds with good quality for tea processing. Shattering is easy, and resistance to leaf blight is medium. ''Hatohikari'' is adaptable to middle mountain regions in chugoku district of Japan. This cultivar has been recommended in Hiroshima prefecture since 1995

  9. Tratamento da dor em queimados

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    Rodrigo José Alencar de Castro

    2013-02-01

    Full Text Available JUSTIFICATIVA E OBJETIVOS: Apesar dos avanços, ainda é observado manejo analgésico inadequado dos pacientes com queimaduras. O objetivo desta revisão foi coletar dados sobre tratamento da dor em queimados. CONTEÚDO: Foi feita revisão sobre os mecanismos de dor, avaliação do paciente com queimadura e o tratamento farmacológico e não farmacológico. CONCLUSÕES: O manejo da dor em pacientes vítimas de queimaduras ainda é um desafio por parte da equipe multiprofissional. A avaliação frequente e contínua da resposta apresentada pelo paciente é muito importante, tendo em vista os vários momentos por que passa o paciente internado em decorrência de uma queimadura, além de uma terapêutica combinada com medicações analgésicas e medidas não farmacológicas. Entender a complexidade de alterações fisiopatológicas, psicológicas e bioquímicas apresentadas por um paciente em tratamento de queimadura é o primeiro passo para alcançar o sucesso no seu manejo analgésico.

  10. Development and deployment of a novel ''yellow'' demulsifier for the gullfaks ''A'' platform

    Energy Technology Data Exchange (ETDEWEB)

    Jackson, S.J.; Ingebrigtsen, T.; Breen, P.J.; Waage, J.; Thorstenson, T.; Melby, S.

    2006-03-15

    Oil producers are increasingly under pressure to produce their product in an environmentally sound manner. Releases to the environment are undesirable and, where permitted to make such releases, oil producers should minimise their environmental impact. The bulk of treatment chemicals designed to improve separation and provide clean water for disposal can themselves be harmful to the environment and must conform to very stringent rules to be considered environmentally acceptable, or ''green''. Here we present data on the development of a green demulsifier for Statoil's Gullfaks ''A'' platform, which not only meets the very stringent regulations but also exhibits a significant improvement in product performance. While the''bottle test'' remains the industry standard method for selecting demulsifiers, in recent years the ''mini trial'' method for product selection has gained favour. We describe using a combination of both methods for the development of the novel demulsifier technology described here. (Author) (tk)

  11. The strategic ''pull'' and operational ''push'' of total quality management in UK regional electricity service companies

    Energy Technology Data Exchange (ETDEWEB)

    McAdam, R.; McLean, J.; Henderson, J.

    2003-04-30

    The aim of this paper is to evaluate whether the UK regional electricity companies (RECs) has used total quality management (TQM) as a ''push'' or as a ''pull'' change methodology. ''Push'' is the operational improvement role of TQM; ''pull'' is the strategic or direction giving, improvement role of TQM. Following the onset of privatisation in 1990 there has been evidence of the RECs adopting TQM in both ''push'' and ''pull'' methodologies with varying degrees of success. An evaluation of the change processes involved will enable improved change models to be developed leading to increased business effectiveness in this 30 billion pounds sterling industry. Other possible benefits include the possible generalisations to other utilities such as water, roads, gas and telecoms. The research methodology includes a comparative case study analysis of five RECs, which have used TQM as their overarching approach to change. One of the cases is analysed to a more in-depth level based on the multiple case findings. The findings indicate that the ''push-pull'' analysis enables the full range of TQM activities to be evaluated in the RECs studied. Overall, there is a need to have a balanced portfolio of operational or ''push''-based TQM activity that is driven by strategic or ''pull'' based TQM planning and activity. (author)

  12. Considerações sobre o tratamento das mastites

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    Helio Langoni

    Full Text Available RESUMO: A mastite é considerada o maior problema dos animais destinados à produção de leite. Altera a sua composição e aumenta a contagem de células somáticas (CCS. Os micro-organismos envolvidos na doença podem ser origem infecciosa, como Staphylococcus aureus, ou ambiental, tal como Escherichia coli. A cultura bacteriana é uma ferramenta de diagnóstico e auxilia na detecção do patógeno causador da mastite. No entanto, fatores como fagocitose podem desencadear um resultado negativo. Quando estabelecido um programa de controle de mastite, o diagnóstico precoce e o início do tratamento adequado dos casos clínicos são fundamentais para se atingir os objetivos e seu sucesso, está relacionado com o patógeno envolvido. A indicação do tratamento de longa duração, ou terapia estendida, tem melhorado a resposta ao tratamento em casos de mastite por S. aureus, no entanto, com 30-50% de cura. Do ponto de vista do manejo dos animais, devido a alta contagiosidade deste patógeno, sua persistência no rebanho e custo em função ao tratamento, muitas vezes, o descarte do animal tem sido priorizado a fim de controlar os casos de mastite em propriedades. As medidas de controle são muito importantes para contribuir com a redução de casos de mastite por este patógeno. A indicação do tratamento intramamário associada com sistêmico tem poder efetivo em casos de mastite por E. coli, cujos casos agudos apresentam-se com sepse e toxemia. São abordados ainda aspectos de tratamentos alternativos das mastites, utilizados principalmente no processo orgânico de produção leiteira.

  13. Tratamento conservador na síndrome do impacto no ombro

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    Carlos Alexandre Batista Metzker

    Full Text Available INTRODUÇÃO: A síndrome do impacto no ombro (SIO é uma patologia inflamatória e degenerativa que se caracteriza por impactação mecânica de determinadas estruturas que se localizam no espaço umerocoracoacromial da articulação. É a afecção mais comum da cintura escapular com prevalência superior em indivíduos com idade entre 40 e 50 anos, entretanto, por estar intimamente relacionada a algumas atividades laborais e esportivas, se torna cada vez mais frequente em adultos jovens. Mediante o elevado número de pacientes acometidos e com o intuito de orientar os diversos profissionais de saúde sobre a necessidade de tratamento precoce da patologia, é objetivo deste estudo apresentar os modelos de tratamento para SIO e a importância da fisioterapia no tratamento conservador. METODOLOGIA: Foi realizada uma revisão da literatura científica com acesso a diversas obras literárias sobre o tema e busca de artigos de periódicos nacionais e internacionais na internet. RESULTADOS: O tratamento conservador da SIO envolve um conjunto de procedimentos que passam por medidas analgésicas, anti-inflamatórias e fisioterapia, sendo a última uma ferramenta indispensável no processo de recuperação. CONCLUSÃO: Ao final do estudo pode-se concluir que o tratamento conservador é frequentemente utilizado no tratamento da SIO e a fisioterapia a modalidade terapêutica mais indicada, associada a um programa de orientação e reeducação quanto às atividades que possam dificultar o processo de recuperação plena. Contudo, o plano de tratamento depende diretamente da fase evolutiva da doença, pois, nos casos de insucesso no tratamento conservador, a cirurgia poderá ser indicada.

  14. Tuberculose: sofrimento e ilusões no tratamento interrompido

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    Wilma Suely Batista Pereira

    1999-06-01

    Full Text Available Estudo realizado em Porto Velho (RO, junto a doentes de tuberculose que interromperam o tratamento. A partir da abordagem qualitativa e do método hermenêutico-dialético de análise do material das entrevistas, foi possível inferir que os sujeitos deste estudo têm pouco conhecimento sobre tuberculose e tomam atitudes relacionadas ao impacto que o diagnóstico e o tratamento prolongado causaram a eles próprios e ao seu meio social. Para os doze entrevistados, a interrupção do tratamento relaciona-se a motivos enraizados no não-dito, efeitos colaterais dos medicamentos, desorganização dos serviços e ilusão de estar curado. Isto implica repensarmos nossas posições técnico-metodológicas e as relações profissional-doente, visando a uma abordagem que possibilite encararmos tuberculose-interrupção de tratamento como experiências vividas pelas pessoas, famílias e redes sociais por elas tecidas ao longo do tempo.

  15. Tratamento medicamentoso da osteoartrose do joelho

    OpenAIRE

    Rezende,Márcia Uchôa de; Gobbi,Riccardo Gomes

    2009-01-01

    O tratamento clínico da osteoartrite/artrose (OA) está sempre indicado e baseia-se no autocuidado feito pelo paciente e orientado pelo médico. O uso de medicamentos é complementar às medidas de emagrecimento, ganho de força, de propriocepção, de flexibilidade e de amplitude de movimento. Entre os medicamentos disponíveis para o tratamento da OA há os que são essencialmente analgésicos e que não interferem no curso da doença; bem como os anti-inflamatórios, controversos por seus efeitos colate...

  16. Tratamento do parkinsonismo com L-Dopa

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    Nilton Luís Latuf

    1972-06-01

    Full Text Available São apresentados os resultados obtidos no tratamento de 54 pacientes parkinsonianos com L-Dopa. A intensidade dos sintomas foi avaliada mediante a escala NUDS (Northwestern University Disability Scales antes e após o tratamento. Os autores ressaltam a obtenção de melhores resultados no que respeita à rigidez e à discinesia, em comparação com o tremor. São apontados os efeitos colaterais, quase sempre de pequena intensidade e corrigíveis com a diminuição ou suspensão da administração medicamentosa.

  17. Aspects of the cosmological ''coincidence problem''

    Energy Technology Data Exchange (ETDEWEB)

    Velten, H.E.S.; Marttens, R.F. vom; Zimdahl, W. [Universidade Federal do Espirito Santo (UFES), Departamento de Fisica, Vitoria, Espirito Santo (Brazil)

    2014-11-15

    The observational fact that the present values of the densities of dark energy and dark matter are of the same order of magnitude, ρ{sub de0}/ρ{sub dm0} ∝ O(1), seems to indicate that we are currently living in a very special period of the cosmic history. Within the standard model, a density ratio of the order of one just at the present epoch can be seen as coincidental since it requires very special initial conditions in the early Universe. The corresponding ''why now'' question constitutes the cosmological ''coincidence problem''. According to the standard model the equality ρ{sub de} = ρ{sub dm} took place ''recently'' at a redshift z ∼ 0.55. The meaning of ''recently'' is, however, parameter dependent. In terms of the cosmic time the situation looks different. We discuss several aspects of the ''coincidence problem'', also in its relation to the cosmological constant problem, to issues of structure formation and to cosmic age considerations. (orig.)

  18. ''de novo'' aneurysms following endovascular procedures

    Energy Technology Data Exchange (ETDEWEB)

    Briganti, F.; Cirillo, S.; Caranci, F. [Department of Neurological Sciences, Services of Neuroradiology, ' ' Federico II' ' University, Naples (Italy); Esposito, F.; Maiuri, F. [Department of Neurological Sciences, Services of Neurosurgery, ' ' Federico II' ' University, Naples (Italy)

    2002-07-01

    Two personal cases of ''de novo'' aneurysms of the anterior communicating artery (ACoA) occurring 9 and 4 years, respectively, after endovascular carotid occlusion are described. A review of the 30 reported cases (including our own two) of ''de novo'' aneurysms after occlusion of the major cerebral vessels has shown some features, including a rather long time interval after the endovascular procedure of up to 20-25 years (average 9.6 years), a preferential ACoA (36.3%) and internal carotid artery-posterior communicating artery (ICA-PCoA) (33.3%) location of the ''de novo'' aneurysms, and a 10% rate of multiple aneurysms. These data are compared with those of the group of reported spontaneous ''de novo'' aneurysms after SAH or previous aneurysm clipping. We agree that the frequency of ''de novo'' aneurysms after major-vessel occlusion (two among ten procedures in our series, or 20%) is higher than commonly reported (0 to 11%). For this reason, we suggest that patients who have been submitted to endovascular major-vessel occlusion be followed up for up to 20-25 years after the procedure, using non-invasive imaging studies such as MR angiography and high-resolution CT angiography. On the other hand, periodic digital angiography has a questionable risk-benefit ratio; it may be used when a ''de novo'' aneurysm is detected or suspected on non-invasive studies. The progressive enlargement of the ACoA after carotid occlusion, as described in our case 1, must be considered a radiological finding of risk for ''de novo'' aneurysm formation. (orig.)

  19. Characterization and behavior in the environment of the crude oil ''Prestige''; Caracterisation et comportement dans l'environnement du fioul ''Prestige''

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2003-03-01

    This study presents analysis realized on the crude oil of the tanker ''Prestige'' which sunk the 19 november 2002. The specifications on the product and its behavior in sea water are detailed. All the analysis are compared to the ''Erika'' crude oil. (A.L.B.)

  20. ''Old'' locked inflation

    Energy Technology Data Exchange (ETDEWEB)

    Liu, Yang; Piao, Yun-Song [College of Physical Sciences, Graduate University of Chinese Academy of Sciences, Beijing 100049 (China); Si, Zong-Guo, E-mail: liuyangbyf@mail.sdu.edu.cn, E-mail: yspiao@gucas.ac.cn, E-mail: zgsi@sdu.edu.cn [Department of Physics, Shandong University, Jinan 250100 (China)

    2009-05-15

    In this paper, we revisit the idea of locked inflation, which does not require a potential satisfying the normal slow-roll condition, but suffers from the problems associated with ''saddle inflation''. We propose a scenario based on locked inflation, however, with an alternative evolution mechanism of the ''waterfall field'' {phi}. Instead of rolling down along the potential, the {phi} field will tunnel to end the inflation stage like in old inflation, by which the saddle inflation could be avoided. Further, we study a cascade of old locked inflation, which can be motivated by the string landscape. Our model is based on the consideration of making locked inflation feasible so as to give a working model without slow roll; It also can be seen as an effort to embed the old inflation in string landscape.

  1. Resultados do tratamento da pancreatite aguda grave

    Directory of Open Access Journals (Sweden)

    Franz Robert Apodaca-Torrez

    Full Text Available OBJETIVO: Avaliar os resultados do Protocolo de Atendimento de pacientes com diagnóstico de pancreatite aguda grave. MÉTODOS: Foram analisados, consecutivamente, a partir de janeiro de 2002, idade, sexo, etiologia, tempo de internação, tipo de tratamento e mortalidade de 37 pacientes portadores de pancreatite aguda grave. RESULTADOS: A idade dos pacientes variou de 20 a 88 anos (média de 50 anos; 27% foram do sexo feminino e 73% do masculino. O tempo médio global de internação foi 47 dias. Treze pacientes foram tratados cirurgicamente; a média de operações realizadas foi duas por paciente. Ocorreram seis óbitos dentre os pacientes submetidos ao tratamento cirúrgico (46% e dois óbitos no grupo submetido somente ao tratamento clínico (8,3%. A mortalidade global foi 21% CONCLUSÃO: Após a modificação na forma de abordagem dos pacientes com pancreatite aguda grave, houve diminuição da mortalidade e uma tendência para a conduta expectante.

  2. ''House in park'' gold plated. Subsequent certification for the new office building; ''Haus im Park'' vergoldet. Nachtraegliche LEED-Zertifizierung fuer neues Buerogebaeude

    Energy Technology Data Exchange (ETDEWEB)

    Herzog, Kati; Wildhack, Alice [Bilfinger Berger AG, Mannheim (Germany). Abt. Nachhaltigkeit/Energieeffizienz

    2011-07-01

    In March 2011, the ''house in park'' received the signet LEED {sup registered} of the U.S. Green Building Council (Washington, North Carolina, U.S.A.) in ''gold''. In general, it is the second German project that was awarded with ''gold'' in the certification version ''New Construction, version 2009''. The special challenge: In the planning phase, no aspects relevant to planning and execution with regard to LEED were implemented. In total there are 15 LEED-certified buildings actually in Germany (worldwide: 7,894). 115 Projects are registered (worldwide: 23,238). The trend is increasing, both nationally as well as internationally.

  3. Tecnologias e sistemas de tratamento para os dejetos da suinocultura

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    Leandro D. dos Santos

    2015-03-01

    Full Text Available A suinocultura caracteriza-se como uma atividade de alto impacto ambiental, devido a grande quantidade de dejetos com alta carga de poluentes, lançados no meio ambiente. No entanto, existem diversas tecnologias, e sistemas de tratamento, com a capacidade de reduzir o poder poluente dos dejetos da suinocultura. O presente trabalho tem como objetivo analisar as principais tecnologias e sistemas de tratamentos para os dejetos da suinocultura, presentes em publicações brasileiras. Os resultados obtidos nestas publicações apresentaram-se de certa forma satisfatórios em relação à redução da carga de poluentes dos efluentes da suinocultura. Entretanto, pouco se sabe sobre o comportamento da redução dos poluentes em função de parâmetros dimensionais e temporais das tecnologias ou dos sistemas de tratamento. Tal desconhecimento dificulta o dimensionamento de sistemas de tratamento, desconsiderando a relação existente entre investimento e redução do poder poluente dos dejetos. Dentro deste contexto, a modelagem e otimização de sistemas pode ser uma ferramenta muito útil para o dimensionamento de tecnologias e sistemas de tratamento de dejetos de suínos.

  4. 'et' special: ''E-world of energy''; 'et'-special: ''E-world of energy''

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2001-02-01

    The 'et' special on the conference 'E-world of energy', held from February 13 - 15, 2001 in Essen (Germany) presents contributions of experts who offer solutions to issues and many topical questions arising in the business of traders and utilities as participants of (international) energy markets at various stages of transition towards workable competition. The translated titles of the 15 contributions reproduced in this 'et' special indicate the major contents of the conference papers: 1. Internet-based wholesale power trading as a competitive option to the power exchange. 2. Forward graphs in European electricity markets. 3. Portfolio management in energy trading. 4. Risk management concepts in energy trading. 5. E-commerce as a driving force of a change in the energy markets. 6. eHuman resources management - a vital aspect of corporate success. 7. A brand policy for electricity? 8. Is it really only the price that counts for the customers? 9. The City Power network: an example of successful customer loyalty strategy for local and regional utilities. 10. The Call Center, an important instrument for customer loyalty programmes. 11. eCommerce or eLlusion? 12. eBusiness as a corporate strategy. 13. Meeting the challenges of increasing IT requirements. 14. IT solutions for transmission and distribution network management. 15. Target costing - pinpointed cost planning and control for the energy supply industry. (orig./CB) [German] In dem 'et'-Special zur Konferenz 'E-world of energy', die vom 13.- 15. Februar 2001 in Essen stattfand, bieten Experten Loesungsvorschlaege fuer die aktuellen Fragen und Probleme an, die sich auf dem Weg zu liberalisierten Energiemaerkten stellen. Die folgenden Titel der 15 Beitraege geben eine Uebersicht ueber den Inhalt der Konferenzbeitraege. Themen: 1. Internetbasierte Grosshandelsmaerkte als Konkurrenz zu Energieboersen 2. Forward-Kurven in europaeischen Strommaerkten 3

  5. XVII International Scientific Conference ''RESHETNEV READINGS''

    International Nuclear Information System (INIS)

    2015-01-01

    The International Scientific Conference 'RESHETNEV READINGS' is dedicated to the memory of Mikhail Reshetnev, an outstanding scientist, chief-constructor of space-rocket systems and communication satellites. The current volume represents selected proceedings of the main conference materials which were published by XVII International Scientific Conference 'RESHETNEV READINGS' held on November 12 – 14, 2013. Plenary sessions, round tables and forums will be attended by famous scientists, developers and designers representing the space technology sector, as well as professionals and experts in the IT industry. A number of outstanding academic figures expressed their interest in an event of such a level including Jaures Alferov, Vice-president of the Russian Academy of Sciences (RAS), Academician of RAS, Nobel laureate, Dirk Bochar, General Secretary of the European Federation of National Engineering Associates (FEANI), Prof. Yuri Gulyaev, Academician of RAS, Member of the Presidium of RAS, President of the International Union of Scientific and Engineering Associations, Director of the Institute of Radio Engineering and Electronics of RAS, as well as rectors of the largest universities in Russia, chief executives of well-known research enterprises and representatives of big businesses. We would like to thank our main sponsors such as JSC ''Reshetnev Information Satellite Systems'', JSC ''Krasnoyarsk Engineering Plant'', Central Design Bureau ''Geophysics'', Krasnoyarsk Region Authorities. These enterprises and companies are leading ones in the aerospace branch. It is a great pleasure to cooperate and train specialists for them. (preface)

  6. Tratamento focal e perifocal contra Aëdes aegypti

    Directory of Open Access Journals (Sweden)

    Milton Moura Lima

    1987-06-01

    Full Text Available Em quatro bairros da cidade do Rio de Janeiro, foram feitos ensaios de tratamento focal com abate granulado a 1 ppm e perifocal com pó molhável de Sumition a 2,5%. Esses tratamentos foram feitos tanto isoladamente quanto em conjunto e, também, associados à aplicação de inseticida a ultrabaixo volume. Os índices prediais, levantados um mês depois de terminado o trabalho, mostraram que o tratamento focal dispensa qualquer medida auxiliar. O tratamento perifocal mostrou-se inócuo e incapaz de impedir o aparecimento de larvas de Aëdes aegypti e de outros insetos, em pneus pintados, na face externa, com Sumition e com Malation.In four districts of the city of Rio dc Janeiro focal treatment essays with granulated Abate at 1 ppm and perifocal treatment essays with wettable powder of Sumithion at 2,5% were performed. These were made either alone or in combination as well as associated to insecticides applied at ultra low volume. The premise indices obtained one month after the treatments indicates that the focal treatment alone is effective, no other addicional methods being necessary. The perifocal treatment is not effective and did not prevent the development of Aedes aegypti larvae and other insects in tires which had their external surface painted with Sumithion and Malathion.

  7. Comportamento da eosinofilia após o tratamento das geohelmintoses

    Directory of Open Access Journals (Sweden)

    Marta Maria Bozóti

    1973-04-01

    Full Text Available A eosinofilia sanguínea após o tratamento anti-helmíntico específico se comportou numa amostragem de 57 crianças da seguinte forma: .Na ascaridíase isolada ou associada à trieuríase a hipereosinofilia parasitária ou descia uniformemente após o tratamento, ou houve primeiro uma exacerbação que durava até a terceira semana após a erradicação da, parasitose, descendo em seguida. Em ambos os casos houve normalização do hemograma em dois meses. Na associação ascaridíase/ancilostomíase também são possíveis dois tipos de comportamento da eosinofilia após tratamento eficaz: ou vai diminuindo a hipereosinofilia, logo em seguida à expulsão dos parasitos, ou há no primeiro mês um aumento da hipereosinofilia (geralmente mais acentuado na primeira semana que se segue ao tratamento, para diminuir após o fim do primeiro mês progressivamente até desaparecer. Na estrongiloidíase e na associação ascaridíase/estrongiloidíase há diminuição constante da hipereosinofilia logo após o tratamento e o hemograma se normaliza em cerca de dois meses. Na trieuríase, a hipereosinofilia, aliás já discreta, diminui pouco com o tratamento. Na ancilostomíase e na associação ancilostomíase/trieuríase a hipereosinofilia ou desce após o tratamento gradativo e lentamente, ou primeiro há uma exaltação temporária nas primeiras três semanas após a terapêutica, para diminuir em seguida. Na associação ancilostomíase/estrongiloidíase também se encontram esses dois tipos de comportamento da hipereosinofilia verminótica, mas a exacerbação da hipereosinofilia, que ocorre na metade dos casos, só dura duas semanas; a regressão eosinofílica ocorre dois meses após o tratamento. Nas tri e tetraeparasitoses a involução pós-terapêutica da hipereosinofilia é irregular e a normalização das taxas sanguíneas de eosinófilos é sempre arrastada, principalmente nas associações ascaridíase/estrongiloidíase/ancilostomíase e

  8. Barreiras ao tratamento da hipertensão arterial

    Directory of Open Access Journals (Sweden)

    Maria Vilani Cavalcante Guedes

    2011-12-01

    Full Text Available Objetivou-se descrever as barreiras encontradas pelas pessoas portadoras de hipertensão arterial para a não adesão ao tratamento e controle dos níveis de sua pressão arterial. Estudo descritivo e transversal realizado em seis unidades básicas de saúde em Fortaleza-Ceará, Brasil, com 246 pessoas inscritas no Programa de Controle de Hipertensão Arterial há, no mínimo, um ano. Coletaram-se dados com entrevista estruturada e no prontuário eletrônico. Identificaram-se 69 pesquisados com níveis pressóricos normalizados. As principais barreiras apontadas foram: baixas condições financeiras, tratamento contínuo com muitos remédios e prática de atividade física. Concluiu-se que as barreiras ao tratamento anti-hipertensivo compreendem a pessoa adoecida, seu ambiente de vida e acesso aos cuidados de saúde.

  9. A ayahuasca e o tratamento da dependência

    Directory of Open Access Journals (Sweden)

    Marcelo S. Mercante

    2013-12-01

    Full Text Available A ayahuasca é uma bebida psicoativa utilizada por diversos grupos indígenas por toda a Amazônia, assim como por xamãs mestiços (chamados "vegetalistas" e por religiões e grupos independentes no Brasil. Desde a década de 1990 esta bebida vem sendo empregada no tratamento da dependência. Existem atualmente alguns centros espalhados pela América do Sul que realizam este tipo de tratamento. Realizei trabalho de campo em quatro deles, um no Peru e três no Brasil. Neste artigo faço uma pequena descrição etnográfica destes centros e teço algumas considerações sobre o papel da experiência durante o efeito do chá no processo de recuperação da dependência e também da possibilidade deste tipo de tratamento não ser uma mera terapia de substituição.

  10. ''SMART'' MULTIFUNCTIONAL POLYMERS FOR ENHANCED OIL RECOVERY

    Energy Technology Data Exchange (ETDEWEB)

    Charles McCormick; Andrew Lowe

    2004-10-20

    Herein we report the aqueous polymerization of acrylamide using reversible addition fragmentation chain transfer (RAFT) polymerization to perform a comprehensive study on the polymerization of acrylamide. More specifically, the effect of polymerization conditions on the polymerization kinetics, molecular weight control, and blocking ability were examined. With this in mind, it was necessary to prepare ''A'' block (corona of the micelle) from a hydrophilic monomer. The responsive ''B'' block present in the core will be disclosed in the next two reports.

  11. Results of Clinical Tests of Phytopreparation ''Tkis Nobati''

    International Nuclear Information System (INIS)

    Khositashvili, V.; Khositashvili, L.; Atuashvili, N.; Osmanova, V.; Chankseliani, Z.

    2005-01-01

    The present paper deals with the results of the study of natural vegetative extract of Folium pini. On the basis of multiple experiments it has been established that phytopreparation ''Tkis Nobati'' strengthens the leucocytoprotection of organism and improves physiological state in oncologic patients in the process of chemoradiotherapy treatment. The preparation ''Tkis Nobati'' provides the elimination of heavy metals from the organism. (author)

  12. First monitoring report ''The future of the power''; Erster Monitoring-Bericht ''Energie der Zukunft''

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-12-15

    The Federal Government has initiated the reconstruction of the energy supply towards a highly efficient and renewable energy systems using the energy concept from September, 2010, and using the energy political resolutions from June, 2011. The energy policy turnaround is ambitioned in its objectives as well as broadly defined. In order to consider the energy policy turnaround as well as the development of the energy market continuously, the Federal Government initiated the monitoring process ''Energy of the future'' with the aim to review regularly the implementation of the measures of the energy concepts as well as the progress in the goal achievement with a view on a secure, economical and environmentally compatible energy supply. The first monitoring report ''Energy of the future'' under consideration is the onset of this process. This report is an important basis for the current fact-based attendance of the energy policy turnaround.

  13. Efeito da eutonia no tratamento da fibromialgia

    OpenAIRE

    Maeda,Cecília; Martinez,José Eduardo; Neder,Matilde

    2006-01-01

    OBJETIVO: avaliar a eutonia como método terapêutico auxiliar no tratamento da fibromialgia (FM). MÉTODOS: estudou-se um grupo de 20 mulheres, segundo os critérios do American College of Rheumatology (ACR), com duração mínima de seis meses, sem alterações no tratamento medicamentoso ou prescrição de exercícios nesse período. As pacientes foram avaliadas através do questionário de dados sociodemográficos; Escala Visual Analógica (EVA) para dor e questionário genérico de avaliação da qualidade d...

  14. Tratamento anaeróbio de chorume em conjunto com esgoto sanitário

    OpenAIRE

    Felipe de Melo Sales Santos, André

    2009-01-01

    O tratamento de chorume conjuntamente com esgoto sanitário, em reatores tipo UASB, é uma alternativa que possui vantagens e desvantagens como qualquer tecnologia. Os tratamentos anaeróbios são bastante dificultados quando utilizados no tratamento de chorume bruto devido às altas concentrações de substâncias orgânicas, inorgânicas e tóxicas os microrganismos anaeróbios. A diluição do chorume em esgotos sanitário favorece o tratamento anaeróbio pela redução das concentrações de n...

  15. Tratamento da bulimia nervosa: síntese das evidências

    Directory of Open Access Journals (Sweden)

    Bacaltchuk Josué

    1999-01-01

    Full Text Available As duas abordagens terapêuticas mais estudadas para o tratamento da bulimia nervosa (BN são os tratamentos psicológicos, principalmente a terapia cognitivo-comportamental (TCC e o uso de antidepressivos. Os resultados de duas revisões sistemáticas da literatura mostram que a TCC é melhor que fila de espera e que os antidepressivos são superiores ao placebo na remissão a curto prazo dos sintomas bulímicos. A comparação direta das duas abordagens mostra que, quando usados como abordagens exclusivas, a TCC é clinicamente mais eficaz e mais aceita do que os antidepressivos. A associação dos dois tipos de tratamento é clinicamente mais eficaz que cada um isoladamente, mas a aceitação das abordagens psicológicas exclusivas é maior. Como a BN é um transtorno grave e com baixa taxa de remissão espontânea, o tratamento associado, com abordagem multidimensional e multidisciplinar, pode ser indicado.

  16. Financial and tax risks at implementation of ''Chayanda- Lensk'' section of ''Sila Sibiri'' gas transportation system construction project

    International Nuclear Information System (INIS)

    Sharf, I V; Chukhareva, N V; Kuznetsova, L P

    2014-01-01

    High social and economic importance of large-scale projects on gasification of East Siberian regions of Russia and diversifying gas exports poses the problem of complex risk analysis of the project. This article discusses the various types of risks that could significantly affect the timing of the implementation and effectiveness of the project for the construction of the first line of ''Sila Sibiri'', the ''Chayanda-Lensk'' section. Special attention is paid to financial and tax aspects of the project. Graphically presented analysis of the dynamics of financial indicators reflect certain periods of effectiveness in implementing the project. Authors also discuss the possible causes and consequences of risks

  17. Aspectos psicossociais na era dos novos tratamentos da AIDS

    Directory of Open Access Journals (Sweden)

    Eduardo Augusto Remor

    Full Text Available O presente artigo descreve o impacto no bem-estar (ansiedade e depressão e qualidade de vida das pessoas HIV+ quando o tratamento anti-retroviral não apresenta os resultados esperados. Foram avaliadas, através de questionários, as percepções e expectativas com o tratamento anti-retroviral, o nível de ansiedade e depressão, o nível de apoio social e a qualidade de vida percebida em 80 pacientes HIV+ em atendimento em um hospital universitário. Os resultados indicaram que as percepções e expectativas negativas com o tratamento podem modular o estado emocional e impactar negativamente a qualidade de vida das pessoas HIV+; e que um nível de apoio social adequado é capaz de atenuar este impacto negativo.

  18. Radiobiological study of the radioprotective activity of a natural Iranian compound, ''Shir-Khecht''; Etude radiobiologique de l'activite radioprotectrice d'un compose naturel Iranien: le ''Shir-Khecht''

    Energy Technology Data Exchange (ETDEWEB)

    Rouhanizadeh, N. [Commissariat a l' Energie Atomique, 92 - Fontenay-aux-Roses (France). Centre d' Etudes Nucleaires

    1968-01-01

    After reviewing the primary mechanisms of the action of ionizing radiation, the possible mechanisms of the action of radioprotective substances, the various chemical structures having a protective effect and the methods for studying chemical radioprotection, the author presents the results he has obtained with natural Iranian product: ''Shir-Khecht''. Tests with this product at lethal and sublethal doses have been carried out on the rat using various means of introduction. The effect of radiation, both with and without protection, has been studied using histological and biochemical methods. The product examined has, in effect, a protective action; it is, furthermore, non-toxic and active when taken orally. (author) [French] Apres avoir rappele les mecanismes primaires de l'action des rayonnements ionisants, les mecanismes possibles de l'action des substances radioprotectrices, les diverses structures chimiques possedant un effet protecteur et les methodes d'etude de la radioprotection chimique, l'auteur presente les resultats qu'il a obtenus en utilisant un compose naturel iranien: le ''Shir-Khecht''. Des essais de ce produit, chez le rat, par diverses voies d'introduction, a dose letale et subletale ont ete effectues. L'effet des radiations, avec et sans protection, a ete etudie a l'aide de methodes histologiques et biochimiques. Le compose essaye possede un pouvoir protecteur; il est, de plus, non toxique et actif par voie orale. (auteur)

  19. Water source heat pumps at the ''Oceanopolis'' park of Brest; Des PAC sur boucle d'eau au parc ''Oceanopolis'' de Brest

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2000-01-01

    The creation of the new 'polar' and 'tropical' lodges of the 'Oceanopolis' park (aquarium and greenhouses) of Brest (Brittany, France) has led to chose the solution of water source heat pumps for the energy production. More than 30 thermodynamic machineries are used to supply both heat and coldness to the installations. This paper describes the technical characteristics of the heating/refrigerating installations, their energy performances and the estimated cost-benefit aspects. (J.S.)

  20. Investigation of vertebral ''end plate sclerosis''

    Energy Technology Data Exchange (ETDEWEB)

    Lee, S.W. [Dept. of Rehabilitation Sciences, Hong Kong Polytechnic Univ., Hung Hom (Hong Kong); Mathie, A.G.; Jackson, J.E. [Diagnostic Radiology, Royal Postgraduate Medical School, Hammersmith Hospital, London (United Kingdom); Hughes, S.P.F. [Div. of Surgery, Anaesthetics and Intensive Care, London (United Kingdom)

    2001-08-01

    To evaluate the association between vertebral &apos;&apos;end plate sclerosis&apos;&apos; and neck pain. A retrospective study was carried out of lateral cervical spine radiographs with a Picture Archive and Communication System (PACS). Two hundred patients&apos; files were randomly assessed, comprising four equal groups, A to D. The mean ages of the patients were 62{+-}7.4 years, 61{+-}7.5 years, 40{+-}5.6 years and 23{+-}5.6 years respectively. In group A, all patients had symptoms of neck pain and a radiographic diagnosis of &apos;&apos;end plate sclerosis&apos;&apos; of the cervical spine. In groups B to D, asymptomatic patients were recruited and their age groups were 50-69, 30-49 and 10-29 years respectively. Using the PACS, the radiographic density and the sagittal diameter, thickness and area of the end plates at the C5 level were measured. Results and conclusions: No significant differences were found in the radiographic density of the end plates either between the symptomatic and asymptomatic groups (groups A and B), or between different age groups (groups B, C and D). A significant increase in end plate area and thickness was found, however, in both group B (P<0.005) and group C (P<0.01) in comparison with group D. This indicates that the extent of end plate sclerosis increases with age. Our results suggest that the radiographic density of cervical vertebral end plates correlates neither with neck pain nor with increasing age. The radiological sign of &apos;&apos;end plate sclerosis&apos;&apos; may be over-reported, further limiting its value in the assessment of patients with cervical spondylosis. (orig.)

  1. Comparison of PCDD/Fs levels and profiles in leachates from &apos;'new'&apos; and &apos;'old'&apos; municipal landfills

    Energy Technology Data Exchange (ETDEWEB)

    Dudzinska, M.; Czerwinski, J.; Rut, B. [Lublin Univ. of Technology (Poland)

    2004-09-15

    Although the presence of PCDD/Fs in landfill leachates has been confirmed, not many experiments have been undertaken in this area, probably because of a very low solubility of PCDD/Fs in water. Modern, properly designed landfills should secure (seal) all deposited wastes and possible leakings within the damp. Leachates are collected and treated on the site or transported to a wastewater treatment plant, so they should not cause a release of any pollutants into the soil or groundwater. But PCDD/Fs as well as a number of chlorinated compounds, which may act as precursors of dioxins under aerobic or anaerobic conditions have been identified as trace contaminants in municipal wastes. The formation of dioxins during municipal waste deposition has not been studied, contrary to the formation of OCDD from precursors under aerobic conditions during composting of waste or treatment of sewage sludge5. Some information about the possible dioxin formation during landfilling might be obtained from the comparison of PCDD/F levels in the leachates from &apos;&apos;old - closed&apos;&apos; and &apos;'new'&apos; sites.

  2. Tendinopatia patelar: resultados tardios do tratamento cirúrgico

    Directory of Open Access Journals (Sweden)

    Marcos Henrique Frauendorf Cenni

    2015-10-01

    Full Text Available resumo Objetivo: Avaliar os resultados tardios do tratamento cirúrgico na tendinopatia patelar (TP com o uso do escore Visa (Victorian Institute of Sport Tendon Study Group e o método de Verheyden. Métodos: Estudo retrospectivo que avaliou os resultados pós-operatórios de 12 pacientes, ou 14 joelhos, entre julho de 2002 e fevereiro de 2011. Foram incluídos os pacientes com tendinopatia patelar refratários ao tratamento conservador e que não apresentavam outras lesões cirúrgicas concomitantes. Pacientes que não foram devidamente acompanhados no período pós-operatório foram excluídos. Resultados: Pelo método de Verheyden, nove pacientes foram considerados muito bons, dois bons e um ruim. Em relação ao Visa, a média foi de 92,4 pontos, com apenas dois pacientes abaixo de 70 pontos (66 e 55 pontos. Conclusão: O tratamento cirúrgico da tendinopatia patelar, quando corretamente indicado, tem bons resultados em longo prazo.

  3. Case story for upgrading of a &apos;'hot'&apos; ESP; Modernisation d&apos;un precipitateur electrostatique &apos;'chaud'&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Chidambaram, T.V.S; Christensen

    2001-06-01

    The &apos;Hot&apos; Electrostatic Precipitator (ESP) equipped with COROMAX pulse system is a very attractive solution for dedusting of the &apos;Hot&apos; exhausted gases from the cement kilns especially on cement plants, where good quality of water is not available on the site. Furthermore, the Electrostatic Precipitator is still the preferred solution in the cement plants for dedusting the cement kiln. It is favored because of its high degree of reliability, its low power consumption, and its low maintenance cost. (author)

  4. Post-Copenhagen: the &apos;new&apos; math, legal &apos;additionality&apos; and climate warming

    Energy Technology Data Exchange (ETDEWEB)

    Ferrey, Steven

    2010-05-15

    Control of carbon emissions to the atmosphere is the environmental issue of this decade - perhaps of this entire generation. Its importance has been equated to the survival of the planet. It may all come down to the novel legal concept that sounds like second-grade math: &apos;'additionality.'&apos; However, it is the &apos;'new'&apos; math. (author)

  5. Preparation of data relevant to &apos;&apos;Equivalent Uniform Burnup&apos;&apos; and Equivalent Initial Enrichment&apos;&apos; for burnup credit evaluation

    Energy Technology Data Exchange (ETDEWEB)

    Nomura, Yasushi; Okuno, Hiroshi [Japan Atomic Energy Research Inst., Tokai, Ibaraki (Japan). Tokai Research Establishment; Murazaki, Minoru [Tokyo Nuclear Service Inc., Tokyo (Japan)

    2001-11-01

    Based on the PWR spent fuel composition data measured at JAERI, two kinds of simplified methods such as &apos;&apos;Equivalent Uniform Burnup&apos;&apos; and &apos;&apos;Equivalent Initial Enrichment&apos;&apos; have been introduced. And relevant evaluation curves have been prepared for criticality safety evaluation of spent fuel storage pool and transport casks, taking burnup of spent fuel into consideration. These simplified methods can be used to obtain an effective neutron multiplication factor for a spent fuel storage/transportation system by using the ORIGEN2.1 burnup code and the KENO-Va criticality code without considering axial burnup profile in spent fuel and other various factors introducing calculated errors. &apos;&apos;Equivalent Uniform Burnup&apos;&apos; is set up for its criticality analysis to be reactivity equivalent with the detailed analysis, in which the experimentally obtained isotopic composition together with a typical axial burnup profile and various factors such as irradiation history are considered on the conservative side. On the other hand, Equivalent Initial Enrichment&apos;&apos; is set up for its criticality analysis to be reactivity equivalent with the detailed analysis such as above when it is used in the so called fresh fuel assumption. (author)

  6. A highly luminescent dinuclear Eu(III) complex based on 4,4&apos;-bis (4&apos;&apos;,4&apos;&apos;,4&apos;&apos;-trifluoro-1&apos;&apos;,3&apos;&apos;-dioxobutyl)-o-terphenyl for light-emitting diodes

    Energy Technology Data Exchange (ETDEWEB)

    Liu Shenggui [State Key Laboratory of Optoelectronic Materials and Technologies, Ministry of Education Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275 (China); School of Chemistry Science and Technology, Zhanjiang Normal University, New Materials Engineering and Technology Development Center of University in Guangdong, Zhanjiang 524048 (China); He Pei; Wang Huihui; Shi Jianxin [State Key Laboratory of Optoelectronic Materials and Technologies, Ministry of Education Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275 (China); Gong Menglian, E-mail: cesgml@mail.sysu.edu.cn [State Key Laboratory of Optoelectronic Materials and Technologies, Ministry of Education Laboratory of Bioinorganic and Synthetic Chemistry, School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou 510275 (China)

    2009-08-15

    A dinuclear Eu(III) complex Eu{sub 2}(btbt){sub 3}.4H{sub 2}O.CH{sub 3}CH{sub 2}OH.N(CH{sub 2}CH{sub 3}){sub 3} was synthesized, where H{sub 2}(btbt) was 4,4&apos;-bis (4&apos;&apos;,4&apos;&apos;,4&apos;&apos;,-trifluoro-1&apos;&apos;,3&apos;&apos;-dioxobutyl)-o-terphenyl. The composition and structure of the complex were characterized by elemental analysis, IR, UV-vis and FAB-MS spectroscopy. The complex emits the characteristic red luminescence of Eu{sup 3+} ion due to the {sup 5}D{sub 0} {yields} {sup 7}F{sub J} (J = 0-4) transitions under {approx}395 nm-light excitation with good luminescent quantum efficiency (32%) and exhibits high thermal stability (337 deg. C). Bright red light-emitting diodes (LEDs) were fabricated by coating the complex onto a {approx}395 nm-emitting InGaN chip. When the mass ratio of the red phosphor to the silicone is 1:30, the efficiency of the fabricated LEDs with the europium complex is 0.98 lm w{sup -1}. The CIE chromaticity coordinates of the LEDs are x = 0.6057 and y = 0.3137, which are close to the National Television Standard Committee (NTSC) standard values for red color. The results indicate that the complex may act as a red component in the fabrication of near UV InGaN-based white light-emitting diodes with high color-rendering index.

  7. A new soybean variety &apos;'Ichihime'&apos;

    International Nuclear Information System (INIS)

    Hajika, M.; Takahashi, M.; Igita, K.; Sakai, S.; Nakazawa, Y.

    2002-01-01

    Ichihime, a new soybean variety registered as &apos;&apos;Soybean Norin 103&apos;&apos;, was developed at Kyushu National Agricultural Experiment Station in 1995. It was selected from the progeny induced by a cross between Kankei 2 and Kankei 1 using gamma-ray irradiation. &apos;'Ichihime'&apos; is a medium-early maturing variety with determinate growth. It has broad leaflets, and purple flowers. The color of its pubescence is light tawny and its pods are dark brown. The main stem length, number of main stem nodes, and seed size are medium. It has strong resistance to the soybean mosaic virus (SMV), medium resistance to the soybean cyst nematode, and medium resistance to purple seed stain. The yield of Ichihime is slightly lower than Suzuyutaka, but classified as medium. The protein components of its seeds are medium and the firmness of the tofu (soybean curd) is the same as that of Suzuyutaka. Ichihime lacks all seed lipoxygenase isozymes and is recommended for new type of soybean food processing materials. Ichihime is suitable for growth in the southern part of the Tohoku area and the northern part of the Kanto area

  8. Hippocampal &apos;&apos;gliosis only&apos;&apos; on MR imaging represents a distinct entity in epilepsy patients

    Energy Technology Data Exchange (ETDEWEB)

    Hattingen, Elke; Enkirch, Simon Jonas; Jurcoane, Alina; Kruse, Maximilian [University Clinics Bonn, Neuroradiology, Department of Radiology, Bonn (Germany); Delev, Daniel [University Clinics Bonn, Department of Neurosurgery, Bonn (Germany); University Clinics Freiburg, Department of Neurosurgery, Freiburg (Germany); Grote, Alexander [University Clinics Bonn, Department of Neurosurgery, Bonn (Germany); Evangelic Hospital of Bethel, Department of Neurosurgery, Bielefeld (Germany); Becker, Albert [University Clinics Bonn, Institute of Neuropathology, Bonn (Germany)

    2018-02-15

    The purpose of this study is to evaluate whether patients with drug-resistant mesial temporal lobe epilepsy (TLE) due to hippocampal &apos;&apos;gliosis only&apos;&apos; have different MRI features than those with hippocampal sclerosis (HS). Most TLE patients have HS corresponding to severe neuronal loss and gliosis, but a few have &apos;&apos;gliosis only&apos;&apos; without significant reduction of neuronal density. We analyzed the morphology of cerebral 3 T MRIs (T1, T2, and FLAIR) of 103 patients with HS and 20 with &apos;&apos;gliosis only&apos;&apos; concerning hippocampal and amygdala aspect, volumes, and signal intensity (SI) using Fisher&apos;s exact test, Student&apos;s t test, and principal component analysis. Visually, the ipsilateral hippocampus was hyperintense in both groups, but SI was markedly increased in 74% of HS and in 25% of &apos;&apos;gliosis only&apos;&apos; patients; the ipsilateral hippocampus was smaller in 92% of HS and in 50% of &apos;&apos;gliosis only&apos;&apos; patients, and its internal architecture was lost in 57% of HS and 5% of &apos;&apos;gliosis only&apos;&apos; patients; the contralateral hippocampal SI was altered in 25% of HS and in 70% of &apos;&apos;gliosis only&apos;&apos; patients (all p < 0.001). Ipsilateral hippocampus of HS patients had lower volume (mean ± SD 2.86 ± 0.87 ml) compared with that of &apos;&apos;gliosis only&apos;&apos; patients (3.4 ± 1.02 ml) and had higher SI than the contralateral hippocampus of HS patients and then the hippocampus of &apos;&apos;gliosis only&apos;&apos; patients (all p < 0.01). &apos;&apos;Gliosis only&apos;&apos; has different MRI hippocampal characteristics than HS: less volume loss, less increase of the T2-w signal intensity, preservation of internal architecture, and more contralateral affection. (orig.)

  9. Hippocampal &apos;&apos;gliosis only&apos;&apos; on MR imaging represents a distinct entity in epilepsy patients

    International Nuclear Information System (INIS)

    Hattingen, Elke; Enkirch, Simon Jonas; Jurcoane, Alina; Kruse, Maximilian; Delev, Daniel; Grote, Alexander; Becker, Albert

    2018-01-01

    The purpose of this study is to evaluate whether patients with drug-resistant mesial temporal lobe epilepsy (TLE) due to hippocampal &apos;&apos;gliosis only&apos;&apos; have different MRI features than those with hippocampal sclerosis (HS). Most TLE patients have HS corresponding to severe neuronal loss and gliosis, but a few have &apos;&apos;gliosis only&apos;&apos; without significant reduction of neuronal density. We analyzed the morphology of cerebral 3 T MRIs (T1, T2, and FLAIR) of 103 patients with HS and 20 with &apos;&apos;gliosis only&apos;&apos; concerning hippocampal and amygdala aspect, volumes, and signal intensity (SI) using Fisher&apos;s exact test, Student&apos;s t test, and principal component analysis. Visually, the ipsilateral hippocampus was hyperintense in both groups, but SI was markedly increased in 74% of HS and in 25% of &apos;&apos;gliosis only&apos;&apos; patients; the ipsilateral hippocampus was smaller in 92% of HS and in 50% of &apos;&apos;gliosis only&apos;&apos; patients, and its internal architecture was lost in 57% of HS and 5% of &apos;&apos;gliosis only&apos;&apos; patients; the contralateral hippocampal SI was altered in 25% of HS and in 70% of &apos;&apos;gliosis only&apos;&apos; patients (all p < 0.001). Ipsilateral hippocampus of HS patients had lower volume (mean ± SD 2.86 ± 0.87 ml) compared with that of &apos;&apos;gliosis only&apos;&apos; patients (3.4 ± 1.02 ml) and had higher SI than the contralateral hippocampus of HS patients and then the hippocampus of &apos;&apos;gliosis only&apos;&apos; patients (all p < 0.01). &apos;&apos;Gliosis only&apos;&apos; has different MRI hippocampal characteristics than HS: less volume loss, less increase of the T2-w signal intensity, preservation of internal architecture, and more contralateral affection. (orig.)

  10. &apos;&apos;Social capitalism&apos;&apos; in renewable energy generation: China and California comparisons

    Energy Technology Data Exchange (ETDEWEB)

    Clark, Woodrow W. II.; Li, Xing [Clark Strategic Partners, PO Box 17975, Beverly Hills, CA 90210 (United States)

    2010-03-15

    With a population of over 1.3 billion people, demand for renewable energy is expected to grow to a USD $12 billion market in the near term. Under Renewable Energy Law (REL) in February 2005 in the People&apos;s Republic of China (PRC) passed by the National Congress, renewable energy projects will be able to receive a range of financial incentives starting in 2006, which will more than double the PRC current renewable energy generation from 7% to 15% by 2020. Most of the increase will be in hydroelectric generated power. Nonetheless, the nation and especially the provinces are moving rapidly to develop a wide range of renewable energy generation including solar, wind, geothermal and run of the river. Because China practices &apos;&apos;social capitalism&apos;&apos; as expressed in it&apos;s recurrent Five Year National Plans since 1999, the national government and all the provinces have programs, unlike many western and industrialized nations, to &apos;'plan'&apos; and provide for infrastructures. This paper concerns only the energy infrastructure sector and renewable energy generation in particular. The planning process includes financial incentives and investments which are a major part of the Chinese law focused on &apos;&apos;encouraging foreign investment industries&apos;&apos;. The key part of the law is to guarantee long-term power purchase agreements with state owned and controlled &apos;'utilities'&apos;. In short, China may have gotten the economics of the energy sector correct in its concern for planning and finance. The paper develops these energy infrastructure ideas along with the legal and financial requirements as &apos;'lessons'&apos; learned from the USA and especially California. These lessons now apply to China and allow it to learn from the American mistakes. Empirical data will be drawn from work done in China that examine the renewable energy generation and infrastructures and hence allow the RPC and its

  11. Uso da fluoxetina no tratamento da tricotilomania felina

    OpenAIRE

    Sousa,Marlos Gonçalves; Ferreira,Lilian Stefanoni; Gerardi,Daniel Guimarães; Costa,Mirela Tinucci

    2004-01-01

    A tricotilomania ou alopecia psicogênica felina é uma dermatopatia de origem psicogênica, decorrente da lambedura compulsiva do pelame, realizada pelo gato em situações de estresse. Tal distúrbio decorre de alterações neuro-hormonais e pode associar-se à introdução de novos animais e/ou crianças no ambiente. Além de mudanças de manejo e atitude para com o animal, sugere-se o emprego de ansiolíticos no tratamento da doença. A fluoxetina foi utilizada no tratamento de cinco gatos domésticos com...

  12. &apos;&apos;Die Dependance&apos;&apos; - Logistic center of the fair at Francfort; &apos;&apos;Die Dependance&apos;&apos; - Das Logistikzentrum der Messe Frankfurt

    Energy Technology Data Exchange (ETDEWEB)

    Klein, W.; Fleischer, J. [Brendel Ingenieure, Frankfurt/Main (Germany); Hummel, D. [FH Zwickau (Germany)

    2006-07-01

    In early November 2004, the logistic center &apos;&apos;Die Dependance&apos;&apos; was commissioned after a construction time of 21 months. It is the second building (after Hall 3) designed by London&apos;s star architect Nicholas Grimshow for the Frankfurt Fair. The new building will house the fairground managers and the Accente Gastronomie Service GmbH. Accente is a modern caterer for the fairground halls, Its kitchen in the new building is big enough for preparing up to 10,000 meals every day. (orig.)

  13. Switzerland as Europe&apos;s &apos;'battery'&apos;. Wishful dream or reality?; Die Schweiz als &apos;&apos;Batterie Europas&apos;&apos;. Utopie oder Realitaet?

    Energy Technology Data Exchange (ETDEWEB)

    Kammer, Adrian; Zurmuehle, Damian; Salzmann, Michael; Baumgartner, Raphael; Mignone, Domenico [Bernische Kraftwerke (BKW), Bern (Switzerland). Energiewirtschaftliche Planung und Prognose

    2015-04-15

    There are plans for Swiss pumped hydrostorage systems to absorb large quantities of excess electricity from European wind and solar power generation. Model-based analyses have shown however that &apos;'Europe&apos;s battery&apos;&apos;, as Switzerland would like to see itself, will not be needed until the middle of this century. Even if all extension projects currently in progress should be completed, Switzerland will not have sufficient pump capacity or import capacity to absorb large amounts of excess electricity. Furthermore, the primary means of making storage capacity available for import electricity would be to reduce reservoir power plant capacity. In view of all this Switzerland&apos;s hopes for a role as a major European electricity storage provider appear somewhat exaggerated even in the long-term perspective.

  14. Colistina parenteral no tratamento de infeccoes graves: experiencia em centro unico

    Directory of Open Access Journals (Sweden)

    Marcos Toshyiuki Tanita

    2013-12-01

    Full Text Available Objetivo: Descrever a experiência de um único centro com o uso de colistina para tratar infecções hospitalares causadas por bactérias Gram-negativas resistentes a múltiplos fármacos e identificar fatores associados com lesão renal aguda e mortalidade. Métodos: Estudo longitudinal retrospectivo que avaliou pacientes gravemente enfermos, com infecções causadas por bactérias Gram-negativas resistentes a múltiplos fármacos. Foram considerados elegíveis para este estudo, durante o período compreendido entre janeiro e dezembro de 2008, todos os pacientes adultos com necessidade de tratamento com colistina endovenosa (colistimetato de sódio. As informações coletadas incluem dados demográficos, diagnóstico, duração do tratamento, presença de lesão renal aguda e mortalidade em 30 dias. Resultados: A colistina foi utilizada para tratar uma infecção em 109 de 789 pacientes (13,8% admitidos à unidade de terapia intensiva. A mortalidade em 30 dias observada nestes pacientes foi de 71,6%. Vinte e nove pacientes (26,6% tinham lesão renal prévia ao tratamento com colistina, sendo que seis deles conseguiram recuperar a função renal, mesmo durante o tratamento com colistina. Vinte e um pacientes (19,2% desenvolveram lesão renal aguda durante o tratamento com colistina, sendo que 11 destes pacientes necessitaram ser submetidos à diálise. A variável independentemente associada com a presença de lesão renal aguda foi a pontuação segundo o sistema Sequential Organ Failure Assessment no início do tratamento com colistina (OR=1,46; IC95%=1,20-1,79; p<0,001. Idade (OR=1,03; IC95%=1,00-1,05; p=0,02 e uso de vasopressores (OR=12,48; IC95%=4,49-34,70; p<0,001 foram fatores associados a óbito, segundo um modelo de regressão logística. Conclusões: Disfunção de órgão quando do início do tratamento com colistina associou-se com lesão renal aguda. Em um pequeno grupo de pacientes, pudemos observar uma melhora da função renal

  15. ESTUDO DA PAPILOMATOSE CUTÂNEA EM BOVINOS LEITEIROS: COMPARAÇÃO DE DIFERENTES TRATAMENTOS

    Directory of Open Access Journals (Sweden)

    Luiz Augusto Batista Brito

    2006-10-01

    Full Text Available Avaliação dos tratamentos empregados no controle da papilomatose cutânea bovina em rebanhos leiteiros, utilizando-se 120 animais, de diferentes propriedades, próximas ao município de Goiânia, Goiás. Os animais foram divididos em seis grupos de 20 bovinos, e cinco grupos deles submetidos a diferentes tratamentos, com um grupo controle, portanto. Utilizaram-se como tratamentos a auto-hemoterapia, o clorobutanol, a diaminazina, o levamisole e a autovacina, e todos os grupos foram tratados com um intervalo de sete dias entre as aplicações, consecutivamente, durante quatro semanas. Procedeu-se à avaliação pela análise de variância, pelo teste Qui-quadrado e de Fisher.Os tratamentos não apresentaram diferença significativa quando usados em papilomas do tipo pedunculado; já oclorobutanol e a diaminazina foram os mais eficazes no tratamento de animais com papilomas do tipo plano. PALAVRAS-CHAVE: Bovino, papilomatose, papilomavírus, tratamento.

  16. EFICÁCIA CLÍNICA DO LASER ACUPUNTURAL NO TRATAMENTO DA DESORDEM TEMPOROMANDIBULAR

    Directory of Open Access Journals (Sweden)

    Diego Rodrigues Pessoa

    2016-12-01

    Full Text Available A disfunção temporomandibular (DTM é a condição mais frequente de dor orofacial crônica. A DTM é caracterizada pela a presença de sinais e sintomas na região orofacial. A acupuntura e Terapia a laser de baixa intensidade (TLBI vêm sendo empregadas no tratamento da DTM. A acupuntura consiste na inserção de agulhas em acupontos específicos do corpo para promover efeitos terapêuticos. A TLBI é uma modalidade de tratamento não invasiva, que vem sendo utilizada com frequência na prática clínica para o tratamento das DTM. Diante do exposto, o objetivo deste estudo foi realizar revisão de literatura, acerca da eficácia clinica do laser acupuntural em pacientes com a DTM. O emprego do laseracupuntural no tratamento das DTM favorece o controle antálgico, miorrelaxante e anti-inflamatório, no entanto, são necessárias novas pesquisas acerca do tema para determinar a eficácia do laser acupuntural em longo prazo para o tratamento de desordens temporomandibulares.

  17. Fraturas do côndilo mandibular: classificação e tratamento

    Directory of Open Access Journals (Sweden)

    Manganello Luiz C.

    2002-01-01

    Full Text Available As fraturas do côndilo mandibular, dentre as fraturas faciais, são as que apresentam o maior número de controvérsias quanto ao seu tratamento e maior dificuldade de diagnóstico. A escolha de um tratamento - cirúrgico, bloqueio maxilo-mandibular, fisioterapia elástica ou associação -, está diretamente ligado ao tipo de fratura, à idade do paciente e ao grau de alteração funcional em decorrência da fratura. Os exames por imagens são importantes para o diagnóstico e classificação da fratura, no entanto, os achados clínicos são mais relevantes na indicação de um tratamento cirúrgico ou conservador. Este trabalho tem como objetivo apresentar uma classificação das fraturas do côndilo relacionada com o seu tratamento e relatar dois casos clínicos, sendo um tratado de forma cirúrgica e o outro conservadoramente, discutindo as vantagens e desvantagens do tratamento cirúrgico, bem como as indicações e contra-indicações.

  18. Pumped storage project &apos;&apos;Energiespeicher Riedl&apos;&apos;; Das Projekt Energiespeicher Riedl

    Energy Technology Data Exchange (ETDEWEB)

    Mayr, Dominik [Verbund Hydro Power AG, Vienna (Austria); Schmauss, Juergen [Regierung von Niederbayern, Landshut (Germany); Neuwerth, Sabine [Grenzkraftwerke GmbH, Simbach am Inn (Germany)

    2012-07-01

    The &apos;&apos;Donaukraftwerk Jochenstein AG&apos;&apos; (DKJ) plans at the river power plant Jochenstein on the Danube in the district of Passau, Bavaria, South-east Germany, the construction of a modern pumped-storage hydropower plant with a capacity of 300 megawatts, the pumped storage &apos;&apos;Energiespeicher Riedl&apos;&apos;. The planned plant is a regionally significant project by the Regional Planning act. Therefore, the DKJ as applicant submitted the documents for the regional planning proceedings to the Government of Lower Bavaria, which completed the process with the positive regional planning assessment under provisos on 01.08.2011, which led to an optimization of the project layout. (orig.)

  19. Rosuvastatina e ciprofibrato no tratamento da dislipidemia em pacientes com HIV

    Directory of Open Access Journals (Sweden)

    Hamilton Domingos

    2012-11-01

    Full Text Available FUNDAMENTO: A dislipidemia secundária à terapia antirretroviral potente nos pacientes com HIV está associada à significativa elevação da morbimortalidade cardiovascular por doença aterosclerótica, sendo, portanto, necessário tratamento imediato e eficaz. OBJETIVO: Demonstrar a efetividade e a segurança da rosuvastatina e do ciprofibrato no tratamento da dislipidemia associada à terapia antirretroviral potente em pacientes com HIV. MÉTODOS: Trezentos e quarenta e seis pacientes com dislipidemia foram submetidos a tratamento farmacológico: 200 pacientes com hipertrigliceridemia receberam ciprofibrato (Grupo I; 79 pacientes com hipercolesterolemia receberam rosuvastatina (Grupo II; e 67 pacientes com dislipidemia mista receberam ciprofibrato associado a rosuvastatina (Grupo III. O perfil lipídico foi avaliado antes e após o tratamento hipolipemiante, sendo feita comparação estatística pelo teste de Wilcoxon. Transaminases hepáticas e creatinofosfoquinase foram dosadas para controle de toxicidade hepática e muscular. RESULTADOS: As concentrações séricas de triglicérides e de colesterol total foram significativamente menores do que as obtidas antes do tratamento, para os três grupos experimentais (p < 0,002. Observou-se aumento significativo do HDL colesterol nos grupos experimentais I e III (p < 0,002. Nos grupos I e II, o LDL-colesterol foi significativamente menor (p < 0,001. Nenhum dos pacientes apresentou elevações de transaminases ou de creatinofosfoquinase a níveis de toxicidade significativa. CONCLUSÃO: Os resultados deste estudo demonstram que ciprofibrato, rosuvastatina ou a combinação de ambos pode ser considerada tratamento hipolipemiante efetivo, seguro e com boa tolerância nos pacientes com Aids submetidos à terapia antirretroviral potente.

  20. &apos;&apos;Measuring the Costs of Climate Change Policies&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Montgomery, W. D.; Smith, A. E.; Biggar, S. L.; Bernstein, P.M.

    2003-05-09

    Studies of the costs of climate change policies have utilized a variety of measures or metrics for summarizing costs. The leading economic models have utilized GNP, GDP, the &apos;&apos;area under a marginal cost curve,&apos;&apos; the discounted present value of consumption, and a welfare measure taken directly from the utility function of the model&apos;s representative agent (the &apos;&apos;Equivalent Variation&apos;&apos;). Even when calculated using a single model, these metrics do not necessarily give similar magnitudes of costs or even rank policies consistently. This paper discusses in non-technical terms the economic concepts lying behind each concept, the theoretical basis for expecting each measure to provide a consistent ranking of policies, and the reasons why different measures provide different rankings. It identifies a method of calculating the &apos;&apos;Equivalent Variation&apos;&apos; as theoretically superior to the other cost metrics in ranking policies. When regulators put forward new economic or regulatory policies, there is a need to compare the costs and benefits of these new policies to existing policies and other alternatives to determine which policy is most cost-effective. For command and control policies, it is quite difficult to compute costs, but for more market-based policies, economists have had a great deal of success employing general equilibrium models to assess a policy&apos;s costs. Not all cost measures, however, arrive at the same ranking. Furthermore, cost measures can produce contradictory results for a specific policy. These problems make it difficult for a policy-maker to determine the best policy. For a cost measures to be of value, one would like to be confident of two things. First one wants to be sure whether the policy is a winner or loser. Second, one wants to be confident that a measure produces the correct policy ranking. That is, one wants to have confidence in a policy measure&apos;s ability to correctly rank

  1. ApoE polymorphisms in narcolepsy

    Science.gov (United States)

    Gencik, Martin; Dahmen, Norbert; Wieczorek, Stefan; Kasten, Meike; Gencikova, Alexandra; Epplen, Jorg T

    2001-01-01

    Background Narcolepsy is a common neuropsychiatric disorder characterized by increased daytime sleepiness, cataplexy and hypnagogic hallucinations. Deficiency of the hypocretin neurotransmitter system was shown to be involved in the pathogenesis of narcolepsy in animals and men. There are several hints that neurodegeneration of hypocretin producing neurons in the hypothalamus is the pathological correlate of narcolepsy. The ApoE4 allele is a major contributing factor to early-onset neuronal degeneration in Alzheimer disease and other neurodegenerative diseases as well. Methods To clarify whether the ApoE4 phenotype predisposes to narcolepsy or associates with an earlier disease onset, we have genotyped the ApoE gene in 103 patients with narcolepsy and 101 healthy controls. Results The frequency of the E4 allele of the ApoE gene was 11% in the patient and 15% in the control groups. Furthermore, the mean age of onset did not differ between the ApoE4+ and ApoE4- patient groups. Conclusion Our results exclude the ApoE4 allele as a major risk factor for narcolepsy. PMID:11560764

  2. ApoE polymorphisms in narcolepsy

    Directory of Open Access Journals (Sweden)

    Kasten Meike

    2001-08-01

    Full Text Available Summary Background Narcolepsy is a common neuropsychiatric disorder characterized by increased daytime sleepiness, cataplexy and hypnagogic hallucinations. Deficiency of the hypocretin neurotransmitter system was shown to be involved in the pathogenesis of narcolepsy in animals and men. There are several hints that neurodegeneration of hypocretin producing neurons in the hypothalamus is the pathological correlate of narcolepsy. The ApoE4 allele is a major contributing factor to early-onset neuronal degeneration in Alzheimer disease and other neurodegenerative diseases as well. Methods To clarify whether the ApoE4 phenotype predisposes to narcolepsy or associates with an earlier disease onset, we have genotyped the ApoE gene in 103 patients with narcolepsy and 101 healthy controls. Results The frequency of the E4 allele of the ApoE gene was 11% in the patient and 15% in the control groups. Furthermore, the mean age of onset did not differ between the ApoE4+ and ApoE4- patient groups. Conclusion Our results exclude the ApoE4 allele as a major risk factor for narcolepsy.

  3. Tratamento não-operatório do trauma abdominal fechado

    Directory of Open Access Journals (Sweden)

    Luiz H. M. Mestieri

    2007-05-01

    Full Text Available Introdução - A mudança da rotina operatória para o tratamento não-operatório (TNO de traumas fechados nos órgãos abdominais sólidos é uma das tendências mais notáveis no cuidado aos pacientes politraumatizados nos últimos 14 anos. Médicos estão sentindo-se seguros para aplicar a técnica não-operatória em tais pacientes. Entretanto, surpreende-nos o fato de que, após uma mudança tão radical, nosso conhecimento seja, ainda, baseado em dados retrospectivos. Quesitos importantes, como as taxas de TNO, suas causas e fatores predisponentes foram obtidos, principalmente, através de revisões de prontuário. Objetivo - Análise da literatura científica sobre as possibilidades de tratamento não-operatório dos traumas abdominais fechados. Material e Método - A literatura científica pesquisada consta de 45 publicações de diversas revistas publicadas entre 1990 e 2004. Nosso trabalho foi realizado sob a forma de metanálise comparativa dentre as díspares condutas de tratamento dos traumas abdominais fechados. Conclusão - O trauma abdominal fechado (contuso representa parcela importante dos traumas. Seu tratamento inicialmente era cirúrgico, mas ultimamente vem-se optando pelo tratamento não-operatório, evitando-se, assim, as complicações decorrentes das cirurgias, como infecções e hemorragias. Existem, contudo, indicações adequadas para que seja realizado o tratamento não-operatório, e não existe um consenso sobre a utilização ou não dessa terapêutica em todos os casos. Diversos estudos mostram os órgãos mais afetados no trauma, os critérios de diagnóstico utilizados para identificar as lesões e as considerações sobre o monitoramento do paciente, que levarão à escolha da conduta e aos resultados do tratamento; mas as opiniões divergem.

  4. Report of working committee 4 &apos;&apos;transmission of gases&apos;&apos;; Rapport de la commission 4 &apos;&apos;transport des gaz&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Volskij, E.

    2000-07-01

    Report of the WOC 4 Transmission contains the results of works carried out during 1998-2000 by the Committee members and the three study groups. The most important is: - review of actual situation and prospects for the gas pipeline transmission system development; - report of SG-4.1 &apos;Pipeline Ageing and Rehabilitation&apos;, including analysis of pipeline steels, welding and insulation, methods of rehabilitation, the program of pipeline reconstruction; - report of SG-4.2 &apos;Emission monitoring&apos; including appraisal of gas losses and methods of lowering of methane and other emissions of the gas units in different countries; - report of SG-4.3 &apos;Pipelines Integrity Management and Safety&apos; including basic information on gas pipeline failure intensity, key elements of the Integrity Management System of the gas transmission, methods of risk evaluation and the effectiveness of the approach. (authors)

  5. 2001-2003 &apos;&apos;public utility&apos;&apos; contract between the French government and Gaz de France; Contrat de &apos;&apos;service public&apos;&apos; 2001-2003 entre l&apos;etat et Gaz de France

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-07-01

    The &apos;&apos;public utility&apos;&apos; contract aims at specifying the actions of Gaz de France (GdF), the French gas utility, in terms of national development and public utility presence at the local scale. It extends and completes the &apos;contract of group&apos; established between the government and GdF in the domain of quality of the services offered to clients, development of gas infrastructures and extension of gas supplies, and sustainable development. (J.S.)

  6. Tratamento da anemia ferropriva com ferro por via oral

    Directory of Open Access Journals (Sweden)

    Rodolfo D. Cançado

    Full Text Available A anemia ferropriva permanece como uma das deficiências nutricionais mais frequentes e importantes no mundo. O tratamento com ferro deve ser iniciado preferencialmente por via oral e a investigação apropriada de sua causa é obrigatória. Os autores discutem os compostos com ferro atualmente disponíveis, o perfil de eficácia, segurança e tolerabilidade desses medicamentos, e o plano terapêutico mais adequado possível para o sucesso no tratamento dessa doença tão comum e importante.

  7. Switzerland as Europe&apos;s &apos;'battery'&apos;. Wishful dream or reality?

    International Nuclear Information System (INIS)

    Kammer, Adrian; Zurmuehle, Damian; Salzmann, Michael; Baumgartner, Raphael; Mignone, Domenico

    2015-01-01

    There are plans for Swiss pumped hydrostorage systems to absorb large quantities of excess electricity from European wind and solar power generation. Model-based analyses have shown however that &apos;'Europe&apos;s battery&apos;&apos;, as Switzerland would like to see itself, will not be needed until the middle of this century. Even if all extension projects currently in progress should be completed, Switzerland will not have sufficient pump capacity or import capacity to absorb large amounts of excess electricity. Furthermore, the primary means of making storage capacity available for import electricity would be to reduce reservoir power plant capacity. In view of all this Switzerland&apos;s hopes for a role as a major European electricity storage provider appear somewhat exaggerated even in the long-term perspective.

  8. O tratamento da doenca renal cronica pode afetar a audicao?

    Directory of Open Access Journals (Sweden)

    Priscila Suman Lopez

    2014-01-01

    Full Text Available Introdução: Doença renal crônica (DRC é definida pela presença de lesão renal levando à perda lenta e progressiva da função renal. Objetivo: Comparar testes auditivos entre pacientes com DRC submetidos a diferentes método de tratamento. Material e método: Estudo clínico transversal. Os grupos foram divididos de acordo com o método de tratamento: hemodiálise (n = 35, diálise peritoneal (n =15, conservador (n = 51 e 27 pacientes saudáveis (controle. Pacientes com idade superior a 60 anos, perda auditiva congênita, síndromes genéticas, infecções de orelha média e transplante renal foram excluídos da pesquisa. A avaliação audiológica incluiu audiometria tonal, emissões otoacústicas evocadas transientes e Potencial Evocado Auditivo de Tronco Encefálico (PEATE; e as variáveis avaliadas foram: sexo, idade, diagnóstico de hipertensão arterial e diabetes, estádio da DRC, tempo de diagnóstico do diabetes e da hipertensão arterial, duração da DRC e do tratamento. Resultados: A idade, presença de hipertensão arterial e tempo de DRC foram estatisticamente significantes e controlados. O grupo conservador apresentou piores limiares auditivos na audiometria tonal e o intervalo III-V do PEATE significativamente maior que o da hemodiálise. Conclusão: O tratamento conservador mostrou piores resultados na avaliação auditiva, independente de diabetes e de hipertensão, reforçando que os pacientes submetidos a tratamento para DRC devem realizar avaliação auditiva completa para melhor compreensão da doença e de seus efeitos sobre o sistema auditivo.

  9. Fatores associados a baixa adesao ao tratamento medicamentoso em idosos

    Directory of Open Access Journals (Sweden)

    Noemia Urruth Leao Tavares

    2013-12-01

    Full Text Available OBJETIVO : Analisar fatores associados à baixa adesão ao tratamento medicamentoso em idosos. MÉTODOS : Estudo transversal de base populacional, com amostra representativa de 1.593 indivíduos com 60 anos ou mais, residentes na região urbana de Bagé, RS, em 2008. A amostragem foi realizada em múltiplos estágios. Os dados foram coletados em entrevistas individuais nos domicílios. Analisou-se a associação entre a baixa adesão referida ao tratamento medicamentoso mensurado pelo Brief Medication Questionnaire (BMQ e fatores demográficos, socioeconômicos, comportamentais e de saúde, assistência e prescrição. Foi utilizado modelo de regressão de Poisson para estimar as razões de prevalência bruta e ajustada, os respectivos intervalos de confiança de 95% e p-valor (teste de Wald. RESULTADOS : Cerca de 78,0% dos indivíduos referiram ter usado algum medicamento nos sete dias precedentes à entrevista. Desses, cerca de 1 / 3 foram considerados com baixa adesão ao tratamento. Os fatores significativamente associados à baixa adesão foram: idade (65 a 74 anos, não ter plano de saúde, ter que comprar (totalmente ou em parte os seus medicamentos, ter três ou mais morbidades, possuir incapacidade instrumental para a vida diária e usar três ou mais medicamentos. CONCLUSÕES : A utilização elevada de medicamentos, decorrente da alta prevalência de doenças crônico-degenerativas em idosos, e o acesso ao tratamento devem ser considerados pelos profissionais de saúde para adoção de estratégias que visem diminuir a baixa adesão ao tratamento, aumentando a resolutividade terapêutica e a qualidade de vida desses pacientes.

  10. Facility Management journal special feature on energy. Intelligent energy supply and air conditioning concept for the &apos;&apos;Bonner Bogen&apos;&apos; buildings; Facility Management-Special &apos;'Energie'&apos;. Intelligentes Energie- und Klimakonzept fuer den &apos;&apos;Bonner Bogen&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2009-11-15

    In the &apos;&apos;Bonner Bogen&apos;&apos; construction project, the focus was on resources-saving technology and maximum user comfort, resulting in an integrated planning and implementation process. According to the investor, BonnVisio, the technical infrastructure and energy center of the building - based on groundwater geothermal energy with aquifer storage - is unique in Germany and Europe in terms of size, mode of operation, and efficiency. (orig.)

  11. &apos;Minergie&apos; as an opportunity for trade; &apos;Minergie&apos; als Chance fuer das Gewerbe

    Energy Technology Data Exchange (ETDEWEB)

    Graf, R.; Buergi, H.; Hotz, R.

    2000-07-01

    This collection of short articles is dedicated to the promotion of the Swiss &apos;Minergie&apos; building standard, covering the following points: &apos;Minergie&apos; - a standard for the future; well-insulated and air-tight - two of the three main &apos;Minergie&apos; requirements; solar collectors as a &apos;Minergie&apos; component; radiators for low-energy-consumption buildings; hot water from the sun on six out of seven days; the &apos;Minergie&apos; module as a factor for success; the &apos;Habitus&apos; ventilation unit - a new Swiss product. The first contribution introduces the &apos;Minergie&apos; Standard. Its application in the building and building technical services trades offers from considerable advantages and opportunities for profit. The Standard, which aims to increase the comfort and reduce the energy consumption of buildings, is introduced and the basic principles involved, including energy usage figures, are discussed. A second contribution describes two of the three main requirements for reaching the &apos;Minergie&apos; Standard, air-tightness and good thermal insulation. The main advantage of the standard - a higher level of comfort - is emphasised and an example is given. The third short article takes a look at the use of thermal solar collectors as a source of heat in &apos;Minergie&apos; buildings. A solution involving a combined solar heating and hot-water supply is discussed. The fourth contribution discusses the use of low-temperature radiators in &apos;Minergie&apos; buildings. Examples are given of heat requirements calculation and the factors involved in dimensioning the radiators are discussed. A fifth article describes a commercially available compact solar hot-water system and discusses questions of solar fraction. Returning to basic aspects, the sixth contribution introduces a labelling system for the various components of a &apos;Minergie&apos; building - such as ventilation units, insulation material, radiators, boilers etc

  12. Korea&apos;s 1-watt plan &apos;&apos;Standby Korea 2010&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Kim, Yungrae

    2010-09-15

    Korea announced standby power of all electronics shall be reduced to below 1W by 2010. Ministry of Knowledge Economy (MKE, Korean government) and Korea Energy Management Corporation (KEMCO) established &apos;&apos;Standby Korea 2010&apos;&apos; which is a roadmap to limit standby power below 1W by 2010. Korea implemented mandatory program over a relatively short period of time, incorporating the better elements from the more established national program and adding new initiatives, such as the threat of using mandatory warning label for products that fail to meet standby power targets.

  13. Tratamento de dejetos suínos com biorreator UASB

    Directory of Open Access Journals (Sweden)

    Pablo Costa da Silva

    2014-05-01

    Full Text Available Esse trabalho tem por objetivo analisar a importância do biodigestor UASB no tratamento de dejetos suínos. A suinocultura possui papel importante quanto ao desenvolvimento econômico do Brasil. No entanto, o aumento de produção vem causando problemas ambientais graves, por conta do grande volume de resíduos sólidos gerados pela atividade. O desenvolvimento de métodos de tratamento de dejetos que agreguem valor à produção e respeitem as leis ambientais é um dos grandes desafios do setor. A biodigestão anaeróbia é um dos métodos mais eficazes para o tratamento de dejetos de suinoculturas. Este método de digestão, denominado UASB, tem como característica principal a produção de biogás e de biofertilizante, produto rico em nutrientes, e livre de patógenos. O método oferece vantagens como a promoção do bem estar animal, o aumento da fertilidade do solo, a diminuição da poluição e da emissão de gases geradores do efeito estufa e a melhoria da qualidade de vida, nos centros produtores de suínos, além de minimizar problemas relacionados ao déficit de energia elétrica. Portanto, a utilização de biodigestores UASB para o tratamento de dejetos de suínos é uma opção interessante, que deve ser avaliada com seriedade.

  14. Design and implementation of a &apos;'cheese'&apos; phantom-based Tomotherapy TLD dose intercomparison

    Energy Technology Data Exchange (ETDEWEB)

    Schiefer, Hans; Buchauer, Konrad; Heinze, Simon [Medical Physics Group, Department of Radiation Oncology, St. Gallen (Switzerland); Henke, Guido; Plasswilm, Ludwig [Department of Radiation Oncology, St. Gallen (Switzerland)

    2015-11-15

    The unique beam-delivery technique of Tomotherapy machines (Accuray Inc., Sunnyvale, Calif.) necessitates tailored quality assurance. This requirement also applies to external dose intercomparisons. Therefore, the aim of the 2014 SSRMP (Swiss Society of Radiobiology and Medical Physics) dosimetry intercomparison was to compare two set-ups with different phantoms. A small cylindrical Perspex phantom, which is similar to the IROC phantom (Imaging and Radiation Oncology Core, Houston, Tex.), and the &apos;'cheese'&apos; phantom, which is provided by the Tomotherapy manufacturer to all institutions, were used. The standard calibration plans for the TomoHelical and TomoDirect irradiation techniques were applied. These plans are routinely used for dose output calibration in Tomotherapy institutions. We tested 20 Tomotherapy machines in Germany and Switzerland. The ratio of the measured (D{sub m}) to the calculated (D{sub c}) dose was assessed for both phantoms and irradiation techniques. The D{sub m}/D{sub c} distributions were determined to compare the suitability of the measurement set-ups investigated. The standard deviations of the TLD-measured (thermoluminescent dosimetry) D{sub m}/D{sub c} ratios for the &apos;'cheese'&apos; phantom were 1.9 % for the TomoHelical (19 measurements) and 1.2 % (11 measurements) for the TomoDirect irradiation techniques. The corresponding ratios for the Perspex phantom were 2.8 % (18 measurements) and 1.8 % (11 measurements). Compared with the Perspex phantom-based set-up, the &apos;'cheese'&apos; phantom-based set-up without individual planning was demonstrated to be more suitable for Tomotherapy dose checks. Future SSRMP dosimetry intercomparisons for Tomotherapy machines will therefore be based on the &apos;'cheese'&apos; phantom set-up. (orig.) [German] Die einzigartige Bestrahlungstechnik mit Tomotherapie-Bestrahlungsgeraeten (Accuray Inc., Sunnyvale, CA, USA) erfordert spezifische

  15. Radiological assessment of skull base changes in children with syndromic craniosynostosis: role of &apos;'minor'&apos; sutures

    Energy Technology Data Exchange (ETDEWEB)

    Calandrelli, Rosalinda; D' Apolito, Gabriella; Gaudino, Simona; Stefanetti, Mariangela; Colosimo, Cesare [Universita Cattolica Sacro Cuore, Institute of Radiology, Rome (Italy); Massimi, Luca; Di Rocco, Concezio [Universita Cattolica Sacro Cuore, Institute of Neurosurgery, Rome (Italy)

    2014-10-15

    This study aims to identify the premature synostosis of &apos;'major'&apos; and &apos;'minor'&apos; sutures of the four &apos;&apos;sutural arches&apos;&apos; of the skull and to perform a morphometric analysis in children with syndromic craniosynostosis in order to evaluate changes in the skull base linked with premature suture synostosis. We reviewed multiplanar high-resolution CT images, implemented with 3D reconstructions, from 18 patients with complex syndromic craniosynostosis and compared them with 18 age-matched healthy subjects. We assessed the calvarial sutures and their extension to the skull base, and then we correlated specific types of synostosis with the size, shape and symmetry of the cranial fossae. We found a marked asymmetry of the skull base growth in all patients. The synostotic involvement around the coronal ring caused a reduction in the growth of the anterior and middle fossae. The size of the posterior cranial fossa was related not only to &apos;'major'&apos; but also to &apos;'minor'&apos; suture synostosis of the lambdoid and parieto-squamosal arches. Changes in the skull base and craniofacial axis symmetry are due to structural and functional relationships between &apos;'major'&apos; and &apos;'minor'&apos; skull sutures, suggesting a structural and functional relationship between the neurocranium and basicranium. The early recognition of prematurely closed skull base sutures may help clinicians and neurosurgeons to establish correct therapeutic approaches. (orig.)

  16. Tratamento do hipertireoidismo da Doença de Graves

    OpenAIRE

    Andrade, Vânia A.; Gross, Jorge L.; Maia, Ana Luiza

    2001-01-01

    A Doença de Graves constitui a forma mais comum de hipertireoidismo e três abordagens terapêuticas são atualmente utilizadas: drogas antitireoidianas (DAT), cirurgia e iodo radioativo (131I). As DAT continuam como tratamento de primeira escolha em pacientes com doença leve, bócios pequenos, crianças e adolescentes, e em situações especiais como na gravidez. Por outro lado, o 131I tem sido cada vez mais utilizado, porque é considerado um tratamento seguro, definitivo e de fácil aplicação. O ri...

  17. Experimental project with &apos;&apos;green fingers&apos;&apos;. A monitoring informs on successes and failures of Helsinki&apos;s Eco-City; Experimentelles Projekt mit &apos;&apos;gruenen Fingern&apos;&apos;. Ein Monitoring gibt Auskunft ueber Erfolge und Misserfolge von Helsinkis &apos;'Oeko-Stadt'&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Ulf [Kansas State Univ., Manhattan, KS (United States). Sustainable Architecture and Urban Design

    2012-07-01

    Of all things, at the extreme edge of Europe, the future of the European city is being rethought: with the new neighborhood &apos;'Viikki'&apos; the Finnish capital Helsinki has built their first eco-city. Eight years after its completion it is time for an evaluation. The founders draw a quite self-critical summary. The monitoring of Eco-Viikki is unusually accurate and thus gives interesting insights for other construction projects in Europe.

  18. Regulation imposed to nuclear facility operators for the elaboration of &apos;waste studies&apos; and &apos;waste statuses&apos;; Reglementation imposee aux exploitants d&apos;installations nucleaires pour l&apos;elaboration &apos;&apos;des etudes dechets&apos;&apos; et &apos;&apos;des bilans dechets&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-09-04

    This decision from the French authority of nuclear safety (ASN) aims at validating the new versions of the guidebook for the elaboration of &apos;waste studies&apos; for nuclear facilities and of the specifications for the elaboration of &apos;waste statuses&apos; for nuclear facilities. This paper includes two documents. The first one is a guidebook devoted to nuclear facility operators which fixes the rules of production of waste studies according to the articles 20 to 26 of the inter-ministry by-law from December 31, 1999 (waste zoning conditions and ASN&apos;s control modalities). The second document concerns the specifications for the establishment of annual waste statuses according to article 27 of the inter-ministry by-law from December 31, 1999 (rational management of nuclear wastes). (J.S.)

  19. Emotions, visions and communications. &apos;&apos;Heartbeats inclusive&apos;&apos;; Emotionen, Visionen und Kommunikationen. &apos;&apos;Herzklopfen inklusive&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Rinderknecht, F.M. [Rinspeed AG, Zumikom (Germany)

    2006-07-01

    Emotional aspects become more and more relevant and important in today&apos;s consumer world. It is not only the technical features or the price which influence decisions for buying or not, but non-tangible elements as brand name, image, imaginary value, personal positioning and other emotions. Products become more and more equal as well as their performance sets no differentiation. Therefore marketing and sales strategies call for emotional differentiations. One very successful example on today&apos;s market is the I-Pod - nothing simpler than a MP3-player which fetches three times the monetary revenue and has some times even a waiting list. Why? Because it is &apos;'cool'&apos; and a status symbol to own one. The same thinking needs to be applied in the marketing and sales activities of natural gas as a mobile fuel as well. Having many important functional disadvantages over gasoline such as a small number of filling stations, limited range of models offered and sometimes limited range and national offer, not only the financial aspects of saving fuel costs, but the emotional positioning of the buyer is very important: To be environment conscious, to be the first, to be different, to be responsible, to be looked at as a trend-setter, and to possibly have power equal to the equivalent in gasoline engines. (orig.)

  20. Flux quantization in &apos;autistic&apos; magnets

    Energy Technology Data Exchange (ETDEWEB)

    Costa de Beauregard, O.; Vigoureux, J.M.

    1974-03-15

    The Dirac electron theory for the evanescent wave surrounding an infinitely long cylindrical magnet with zero surface polarization and the requirement of the single valuedness of this wave are used to show that the magnetic flux is quantized in units h/2e emu. The same quantization is shown for a general &apos;'autistic'&apos; magnet (i.e. magnet completely trapping its flux), thus establishing complete external equivalence of the &apos;'autistic'&apos; magnet with the &apos;&apos;perfect solenoid&apos;&apos;. An experimental test of the predicted quantization is suggested.

  1. Fatores prognósticos para o desfecho do tratamento da tuberculose pulmonar em Recife, Pernambuco, Brasil

    Directory of Open Access Journals (Sweden)

    Maria de Fatima Militão de Albuquerque

    2001-06-01

    Full Text Available Objetivos. O objetivo deste estudo caso-controle foi identificar fatores prognósticos para desfecho do tratamento da tuberculose pulmonar em 297 pacientes (Hospital das Clínicas, Universidade Federal de Pernambuco, Brasil entre 1994 e 1999. Materiais e métodos. Foram considerados casos indivíduos com alta por óbito, abandono ou falência do tratamento. Os controles foram indivíduos com alta por cura. Foram realizadas análises uni e multivariada com as variáveis independentes sexo; idade; escolaridade; hábito de fumar; hábito de ingerir álcool; tratamento anterior para tuberculose; resposta ao teste tuberculínico; sorologia para HIV; grau de resistência aos antimicrobianos; resultado da pesquisa direta de bacilos álcool-ácido-resistentes; esquema terapêutico utilizado. Além disso, repetiram-se as análises uni e multivariada considerando como casos apenas os óbitos e os indivíduos com falência do tratamento. Resultados. A ingestão excessiva de álcool (OR = 2,58; P = 0,014, a co-infecção pelo HIV (OR = 3,40; P = 0,028, o a tratamento anterior para tuberculose (OR = 4,89; P < 0,001 e resistência a duas ou mais drogas antituberculose (OR = 3,49; P = 0,017 foram fatores de risco para o insucesso do tratamento. Na segunda análise multivariada, excluindo os casos de abandono, não houve associação entre a o ingestão excessiva de álcool e desfecho do tratamento, mantendo-se as demais associações, o que sugere uma estreita relação entre o abandono do tratamento e o etilismo. Conclusões. Os fatores prognósticos para insucesso do tratamento da tuberculose pulmonar entre os indivíduos estudados estão interrelacionados, sendo de natureza biológica, clínica e social. Devem ser identificados no início do tratamento para que sejam implementados procedimentos diferenciados de acompanhamento, tais como tratamento diretamente supervisionado, de forma a fortalecer o controle da tuberculose em nível local.

  2. Spherically symmetric conformal gravity and &apos;&apos;gravitational bubbles&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Berezin, V.A.; Dokuchaev, V.I.; Eroshenko, Yu.N., E-mail: berezin@inr.ac.ru, E-mail: dokuchaev@inr.ac.ru, E-mail: eroshenko@inr.ac.ru [Institute for Nuclear Research, Russian Academy of Sciences, 60th October Anniversary Prospect 7a, Moscow, 117312 (Russian Federation)

    2016-01-01

    The general structure of the spherically symmetric solutions in the Weyl conformal gravity is described. The corresponding Bach equations are derived for the special type of metrics, which can be considered as the representative of the general class. The complete set of the pure vacuum solutions is found. It consists of two classes. The first one contains the solutions with constant two-dimensional curvature scalar of our specific metrics, and the representatives are the famous Robertson-Walker metrics. One of them we called the &apos;&apos;gravitational bubbles&apos;&apos;, which is compact and with zero Weyl tensor. Thus, we obtained the pure vacuum curved space-times (without any material sources, including the cosmological constant) what is absolutely impossible in General Relativity. Such a phenomenon makes it easier to create the universe from &apos;'nothing'&apos;. The second class consists of the solutions with varying curvature scalar. We found its representative as the one-parameter family. It appears that it can be conformally covered by the thee-parameter Mannheim-Kazanas solution. We also investigated the general structure of the energy-momentum tensor in the spherical conformal gravity and constructed the vectorial equation that reveals clearly some features of non-vacuum solutions. Two of them are explicitly written, namely, the metrics à la Vaidya, and the electrovacuum space-time metrics.

  3. Exposição ao vivo no tratamento de agorafobia: relato de caso

    Directory of Open Access Journals (Sweden)

    Gustavo J. Fonseca D'El Rey

    Full Text Available Relato de caso, em que a Exposição ao Vivo foi utilizada no tratamento de paciente com diagnóstico de agorafobia. O tratamento foi realizado em doze sessões, apresentando êxito no uso dessa técnica comportamental.

  4. Adesão de pessoas com diabetes mellitus tipo 2 ao tratamento medicamentoso

    Directory of Open Access Journals (Sweden)

    Lilian Cristiane Gomes-Villas Boas

    2014-04-01

    Full Text Available Estudo seccional de abordagem quantitativa que objetivou avaliar a adesão ao tratamento medicamentoso entre pessoas com diabetes mellitus, e sua relação com variáveis clínicas, de tratamento e controle metabólico. A amostra constituiu-se de 162 pessoas com diabetes mellitus tipo 2 em seguimento ambulatorial. Para a coleta dos dados, foram utilizadas a Medida de Adesão aos Tratamentos e a consulta aos prontuários dos participantes. Obteve-se elevada adesão ao tratamento medicamentoso. Para um p<0,05, obteve-se correlação inversa com a pressão arterial diastólica e correlação direta com a frequência diária de administração de insulina e de antidiabéticos orais. Não houve correlações estatisticamente significantes entre adesão e variáveis de controle metabólico. Os resultados divergem da literatura no que se refere à taxa de adesão ao tratamento medicamentoso em doenças crônicas, bem como na correlação entre adesão e complexidade do regime medicamentoso, o que aponta para a necessidade de mais estudos sobre essa temática.

  5. 66. The safety engineering at reprocessing of raw material from &apos;zero&apos; mark and &apos;slaked lime&apos;

    International Nuclear Information System (INIS)

    Ivanov, A.V.

    1993-01-01

    The safety engineering at reprocessing of raw material from &apos;zero&apos; mark and &apos;slaked lime&apos; was studied. All operational conditions at reprocessing of raw material from &apos;zero&apos; mark and &apos;slaked lime&apos; were discussed.

  6. Deep-sea drilling. Practical aspects of 4D seismic: what an engineer needs to know. Developments in Iran: &apos;SIRRI&apos; of the Total company and &apos;DOROOD&apos; of the Elf company. The &apos;DOROOD&apos; operating plan. The &apos;SIRRI&apos; operating plan; Le forage en eau profonde. Aspects pratiques de la sismique 4D: ce qu&apos;un ingenieur doit savoir. Developpements en Iran: &apos;SIRRI&apos; de Total et &apos;DOROOD&apos; d&apos;Elf. Le projet &apos;DOROOD&apos;. Le projet &apos;SIRRI&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Claverie, P. [Schlumberger Sedco Forex, 92 - Montrouge (France); Bauquis, P.R. [Association Francaise des Techniciens et Professionnels du Petrole, AFTP, 92 - Paris-la-Defense (France); Seiller, B.; Geronimi, X. [Elf France, (France); Barthe, D. [Total Fina, 92 - La Defense (France)

    1999-08-01

    In this &apos;Drilling-Production&apos; section, in which 7 papers are gathered, 3 main topics are developed: (1)the deep-sea drilling (2)the practical aspects of 4D seismic (3)the &apos;SIRRI&apos; and &apos;DOROOD&apos; operating plans in Iran. Concerning the first point, it can be noticed that nowadays, mobile platforms are located in great offshore where water depths are of about 2400 m. In the second point is particularly detailed what 4D is, what it can do, what the primary conditions for it works are and how it costs. The third point is the more particularly detailed in this section (15 pages). At first an introduction indicates why Iran has to call to international petroleum investors, what the current problems of Iran are, what Iran has to do to attract foreign investment and technology and what the challenges to foreign companies are. Then the two operating plans: &apos;SIRRI&apos; and &apos;DOROOD&apos; are exposed into details. A synthesis of these plans, called of &apos;Buy Back&apos;, (production, investment, refund) is given as well as their advantages and disadvantages. (O.M.)

  7. New quality assurance program integrating &apos;&apos;modern radiotherapy&apos;&apos; within the German Hodgkin Study Group

    Energy Technology Data Exchange (ETDEWEB)

    Kriz, J.; Haverkamp, U.; Eich, H.T. [University of Muenster, Department of Radiation Oncology, Muenster (Germany); Baues, C.; Marnitz-Schulze, S. [University of Cologne, Department of Radiation Oncology, Koeln (Germany); Engenhart-Cabillic, R. [University of Marburg, Department of Radiation Oncology, Marburg (Germany); Herfarth, K. [University of Heidelberg, Department of Radiation Oncology, Heidelberg (Germany); Lukas, P. [University of Innsbruck, Department of Radiation Oncology, Innsbruck (Austria); Schmidberger, H. [University of Mainz, Department of Radiation Oncology, Mainz (Germany); Fuchs, M.; Engert, A. [University of Cologne, Department of Internal Medicine, Koeln (Germany)

    2017-02-15

    Field design changed substantially from extended-field RT (EF-RT) to involved-field RT (IF-RT) and now to involved-node RT (IN-RT) and involved-site RT (IS-RT) as well as treatment techniques in radiotherapy (RT) of Hodgkin&apos;s lymphoma (HL). The purpose of this article is to demonstrate the establishment of a quality assurance program (QAP) including modern RT techniques and field designs within the German Hodgkin Study Group (GHSG). In the era of modern conformal RT, this QAP had to be fundamentally adapted and a new evaluation process has been intensively discussed by the radiotherapeutic expert panel of the GHSG. The expert panel developed guidelines and criteria to analyse &apos;'modern'&apos; field designs and treatment techniques. This work is based on a dataset of 11 patients treated within the sixth study generation (HD16-17). To develop a QAP of &apos;&apos;modern RT&apos;&apos;, the expert panel defined criteria for analysing current RT procedures. The consensus of a modified QAP in ongoing and future trials is presented. With this schedule, the QAP of the GHSG could serve as a model for other study groups. (orig.) [German] Nicht nur die Zielvolumendefinitionen haben sich von der Extended-Field- (EF-RT) ueber die Involved-Field- (IF-RT) bis zur Involved-Node- (IN-RT) und Involved-Site-Radiotherapie (IS-RT) weiterentwickelt. Auch die Radiotherapie(RT)-Techniken in der Behandlung von Patienten mit Hodgkin-Lymphom haben Aenderungen erfahren. Wir moechten aufzeigen, wie die Arbeit des Qualitaetssicherungsprogramms (QAP) innerhalb der Deutschen Hodgkin Studiengruppe (German Hodgkin Study Group [GHSG]) in der Aera der &apos;&apos;modernen RT&apos;&apos; hinsichtlich intensitaetsmodulierter RT (IMRT) und bildgefuehrter RT (IGRT), aber auch hinsichtlich moderner Felddefinitionen wie bei der IN-RT angepasst wurde. In der Aera der &apos;&apos;modernen RT&apos;&apos; wurde das QAP vom radiotherapeutischen Expertenpanel der GHSG im Rahmen einiger

  8. Students&apos;, Guardians&apos;, and Teachers&apos; Perceptions of Student-Led Conferences

    Science.gov (United States)

    Orso, Charlotte Lindsey

    2013-01-01

    The purpose of the study was to examine the ELL and non-ELL students&apos;, guardians&apos;, and the English as a second language (ESL) teachers&apos; perceptions of student-led conferences. Specifically, the study examined if ELL students&apos; and guardians&apos; preferences were similar to non-ELL students&apos; and guardians&apos; preferences…

  9. Coral bleaching and ocean &apos;&apos;hot spots&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Goreau, T.J. (Global Coral Reef Alliance, Chappaqua, NY (United States)); Hayes, R.L. (Howard Univ., Washington, DC (United States). College of Medicine)

    1994-05-01

    Global sea-surface temperature maps show that mass coral-reef bleaching episodes between 1983 and 1991 followed positive anomalies more than 1 deg C above long-term monthly averages (&apos;&apos;hot spots&apos;&apos;) during the preceding warm season. Irregular formation, movement, and disappearance of hot spots make their detailed long-term prediction impossible, but they can be tracked in real time from satellite data. Monitoring of ocean hot spots and of coral bleaching is needed if the Framework Convention of Climate Change is to meet its goal of protecting the most temperature sensitive ecosystems. 47 refs, 3 figs

  10. Scenarios for an integrated sustainability policy - using the example of the &apos;&apos;Sustainable City 2030&apos;&apos;. Vol. 2; Szenarien fuer eine integrierte Nachhaltigkeitspolitik - am Beispiel: Die nachhaltige Stadt 2030. Bd. 2. Teilbericht &apos;&apos;Kreislaufstadt 2030&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Verbuecheln, Maic; Grabow, Busso; Uttke, Angela; Schwausch, Mandy [Deutsches Inst. fuer Urbanistik (DiFu), Berlin (Germany); Gassner, Robert [Institut fuer Zukunftsstudien und Technologiebewertung gGmbH (IZT), Berlin (Germany)

    2013-04-15

    The partial report &apos;&apos;Recycling City 2030&apos;&apos; was prepared for the Federal Environment Agency (Dessau, Federal Republic of Germany) as a part of the project &apos;&apos;Scenarios for an integrated sustainability policy - the example of &apos;The Sustainable City 2030 &apos;'&apos;. This partial report is based on research activities of the German Institute of Urban Affairs (Berlin, Federal Republic of Germany) and Institute for Futures Studies and Technology Assessment (Berlin, Federal Republic of Germany). The objectives of this partial report are: (1) Description of the challenges and trends in urban regions; (2) Recycling city and its importance in the current debate on sustainability; (3) Identification and optimization of existing cycle approaches in urban habitats; (4) Analysis of the actual state as well as designation of developments and constraints; (5) Discussion on the interface between the sectors; (6) Options for action for the interaction between the actors in interdisciplinary topics; (7) Outline of ways and perspectives of the implementation of the &apos;&apos;Recycling City 2030&apos;&apos;.

  11. Optimisation of biological reactors using the &apos;biological resonance&apos; phenomenon; Ansatz zur Optimierung biologischer Reinigungsstufen durch das Phaenomen der &apos;&apos;Biologischen Resonanz&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Schmid, A.

    2003-07-01

    The microbial catabolic activity of biological reactors can be increased by up to 75% through external stimulation with intermittent stress loads at intervals of several minutes. Under these process conditions, the &apos;&apos;biological resonance&apos;&apos; phenomenon determines the system and leads to an increased synthesis of enzymes. In addition to computer simulations, experiments with activated sludge were carried out in a 10-litre bioreactor. By modulating the stress intervals, a permanent increase in catabolic activity of about 60% was achieved during these experiments. By relying on the &apos;&apos;biological resonance&apos;&apos; phenomenon, the required reaction volume of biological treatment units can probably be reduced by up to 40%. (orig.)

  12. European day &apos;&apos;in town, without my car&apos;&apos;; Journee europeen &apos;&apos;en ville, sans ma voiture&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-10-01

    70 million inhabitants took part in the day &apos;&apos;In town, without my car&apos;&apos; on 22 September of this year. It is a great success for this European first. The objective of Energie-Cites association being to promote sustainable local energy policies, that is to say policies aimed at improving energy efficiency, increasing the use of renewable energy sources and limiting nuisance and pollution linked to energy consumption, the association is pleased that this event helped focus public attention on transport. It is indeed in this sector that uncontrolled upswings in energy consumption and greenhouse gas emissions are the most important. This report presents the evaluation of this European initiative and details the actions in some towns. (A.L.B.)

  13. Recognizing IT risks - acting with foresight or: &apos;&apos;practical reasons for comprehensive IT security&apos;&apos;; IT-Risiken erkennen, vorausschauend handeln oder: &apos;&apos;Praktische Gruende fuer umfassende IT-Security&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Schaeffer, P.A.R. [TUeV Rheinland Secure iT GmbH, Koeln (Germany)

    2006-07-01

    Comprehensive IT security expects all threats and every possible consequence to be identified in order to deduce and develop appropriate counter measures. This article describes two exemplary threats to an IT infrastructure: &apos;Hacking Internal Networks&apos; and &apos;A High Promising Target: Web Applications&apos;. (orig.)

  14. Agreement &apos;&apos;power networks and environment&apos;&apos; 2001-2003; Accord &apos;&apos;reseaux electriques et environnement&apos;&apos; 2001-2003

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2002-01-01

    This agreement, discussed between the French government and Electricite de France (EdF) group, proposes some engagements for the 2001-2003 era for a better environmental integration of power transmission and distribution networks. The agreement is made of two parts: 1 - public distribution networks: realization of new workmanship (medium and low voltage power lines, new lines in dense urban areas), actions on existing workmanship (consequences of December 1999 storms, aesthetical aspects, burial of the main overhead lines in wooded areas, reinforcement of EdF&apos;s environmental commitment, remedial actions for environmental &apos;black points&apos;), general measures of implementation (increasing network safety, protection of birds fauna, coordination of works); 2 - public transportation network (RTE): development and safety improvement of the public transportation network (reinforced arrangement for the establishment of regional development schemes, development of international interconnections, safety improvement of the public transportation network, RTE&apos;s environmental plan); line projects (arrangements during projects elaboration, accompanying program); long lived RTE&apos;s commitment (environmental management and ISO-14001 certification, vigilance with respect to electromagnetic fields, R and D). (J.S.)

  15. Comportamento da eosinofilia após o tratamento das geohelmintoses

    Directory of Open Access Journals (Sweden)

    Marta Maria Bozóti

    1973-04-01

    Full Text Available A eosinofilia sanguínea após o tratamento anti-helmíntico específico se comportou numa amostragem de 57 crianças da seguinte forma: .Na ascaridíase isolada ou associada à trieuríase a hipereosinofilia parasitária ou descia uniformemente após o tratamento, ou houve primeiro uma exacerbação que durava até a terceira semana após a erradicação da, parasitose, descendo em seguida. Em ambos os casos houve normalização do hemograma em dois meses. Na associação ascaridíase/ancilostomíase também são possíveis dois tipos de comportamento da eosinofilia após tratamento eficaz: ou vai diminuindo a hipereosinofilia, logo em seguida à expulsão dos parasitos, ou há no primeiro mês um aumento da hipereosinofilia (geralmente mais acentuado na primeira semana que se segue ao tratamento, para diminuir após o fim do primeiro mês progressivamente até desaparecer. Na estrongiloidíase e na associação ascaridíase/estrongiloidíase há diminuição constante da hipereosinofilia logo após o tratamento e o hemograma se normaliza em cerca de dois meses. Na trieuríase, a hipereosinofilia, aliás já discreta, diminui pouco com o tratamento. Na ancilostomíase e na associação ancilostomíase/trieuríase a hipereosinofilia ou desce após o tratamento gradativo e lentamente, ou primeiro há uma exaltação temporária nas primeiras três semanas após a terapêutica, para diminuir em seguida. Na associação ancilostomíase/estrongiloidíase também se encontram esses dois tipos de comportamento da hipereosinofilia verminótica, mas a exacerbação da hipereosinofilia, que ocorre na metade dos casos, só dura duas semanas; a regressão eosinofílica ocorre dois meses após o tratamento. Nas tri e tetraeparasitoses a involução pós-terapêutica da hipereosinofilia é irregular e a normalização das taxas sanguíneas de eosinófilos é sempre arrastada, principalmente nas associações ascaridíase/estrongiloidíase/ancilostomíase e

  16. Trends in Energy. &apos;The consumer decides&apos;; Trends in Energy. &apos;De consument bepaalt&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Brzezowsky-Ruys, Y.; Van der Zalm, M.; Van Zutphen, M. (eds.)

    2012-03-15

    A report is given of the Capgemini organised congress &apos;Trends in Energy 2011&apos; which has the Dutch subtitle &apos;De consument bepaalt&apos; (The consumer decides&apos;. The focus of the articles, interviews, debates and presentations is on the role of the consumer in the supply of and demand for energy. Parts of the report are in Dutch and English [Dutch] Dit rapport bestaat uit een verslag van het congres &apos;Trends in Energy 2011. De consument bepaalt&apos; en een aantal artikelen met achtergrondinformatie over onder meer de rol van de consument in vraag en aanbod van energie.

  17. Do we need a &apos;&apos;green medicine&apos;&apos;?; Brauchen wir &apos;&apos;Gruene Medizin?&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Bauer, M.; Daschner, F.; Scherrer, M. [Universitaetsklinikum Freiburg (Germany)

    2006-07-01

    Spontaneously, we do associate &apos;&apos;green medicine&apos;&apos; with terms like naturopathy, natural healing substances, herbal active agents, homeopathy, healthy food, preventive medicine and similar things, and finally we think of ecology. This is the focus of the following article. First of all, the following question arises: Are there any environment-friendly and cost-saving alternatives to the present medicine? There is an increasing number of environment-caused diseases. Therefore, a medicine not coping with the environment is not credible. In today&apos;s medicine, for example, there are too many persistent detergents, water-polluting disinfectants, and many disposable materials. Too much water ist consumed, whereas the use of renewable energies is only limited. And too little natural healing methods are applied in diagnostics and therapy. Presently, in Germany, 16,7 million in-patients are treated in Germany, 1,16 million out-patients have surgeries in 2166 hospitals by ca. 1,1 million medical staff. All this work needs energy and materials which bring various risks to environment and the patients. During the last two decades, however, many efforts were made in the field of environment protection in medicine. There is hardly a hospital left which has not taken measures of protecting the environment. In the branch-specific quality management system KTQ (=cooperation for transparency and quality in the health system). environment protection measures are interrogated and systematically assessed.

  18. &apos;&apos;Is it really green?&apos;&apos; Long-term performance of monocrystalline solar modules as illustrated by the example of a photovoltaic pumping station in a natural reserve (&apos;&apos;Schwenninger Moos&apos;&apos;); &apos;&apos;Is it really green?&apos;&apos; Langzeiterfahrung mit monokristallinen Solarmodulen am Beispiel der photovoltaischen Pumpstation Schwenninger Moos

    Energy Technology Data Exchange (ETDEWEB)

    Assbeck, Franz [Hochschule Furtwangen (Germany). Fakultaet Computer und Electrical Engineering

    2010-03-15

    In 1991, a photovoltaic pumping station was commissioned in the natural reserve &apos;&apos;Schwenninger Moos&apos;&apos; in the southern Black Forest. The pumping station was dismantled when the land was used for the 2010 Baden-Wuerttemberg &apos;Landesgartenschau&apos; (garden festival). After 18 years of operation, the plant provided valuable information on the long-term performance of monocrystalline solar modules, so the author made detailed measurements and evaluations just before the plant was dismantled, in an attempt to find out about its long-term performance and cost efficiency. The results are presented here. (orig.)

  19. The role of &apos;&apos;momentum removal&apos;&apos; in divertor detachment

    Energy Technology Data Exchange (ETDEWEB)

    Kukushkin, A.S. [Kurchatov Institute, Moscow (Russian Federation); NRNU MEPhI, Moscow (Russian Federation); Pacher, H.D. [INRS-EMT, Varennes, Quebec (Canada)

    2016-08-15

    The role of &apos;&apos;momentum removal&apos;&apos; (the drag force on the plasma ion flow) in divertor detachment is considered and analysed in detail. This analysis of the 2D modelling results shows that the drag force cannot reduce the power and particle flux to the target directly. However, it is essential for creating the conditions for efficient radiation and volumetric plasma recombination, which in turn do the job. (copyright 2015 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  20. Development of an object oriented lattice QCD code &apos;'Bridge++'&apos;

    International Nuclear Information System (INIS)

    Ueda, S; Aoki, S; Aoyama, T; Kanaya, K; Taniguchi, Y; Matsufuru, H; Motoki, S; Namekawa, Y; Nemura, H; Ukita, N

    2014-01-01

    We are developing a new lattice QCD code set &apos;'Bridge++'&apos; aiming at extensible, readable, and portable workbench for QCD simulations, while keeping a high performance at the same time. Bridge++ covers conventional lattice actions and numerical algorithms. The code set is constructed in C++ with an object oriented programming. In this paper we describe fundamental ingredients of the code and the current status of development

  1. Outcomes in diabetic foot ulcer patients with isolated T2 marrow signal abnormality in the underlying bone: should the diagnosis of &apos;'osteitis'&apos; be changed to &apos;&apos;early osteomyelitis&apos;&apos;?

    Energy Technology Data Exchange (ETDEWEB)

    Duryea, Dennis; Bernard, Stephanie; Flemming, Donald; Walker, Eric; French, Cristy [Milton S. Hershey Medical Center, Department of Radiology, H066, 500 University Drive, PO Box 850, Hershey, PA (United States)

    2017-10-15

    To evaluate the variability of clinical treatment and outcomes based on reporting of diabetic foot ulcer MRI findings of adjacent marrow T2 hyperintensity with normal T1 signal. A retrospective review was conducted of 46 MRI examinations evaluating diabetic foot ulcers that demonstrated normal T1 marrow signal, but T2 marrow hyperintensity deep to the ulcer. The cohort was divided based on MRI report impressions into three groups; &apos;&apos;osteitis without osteomyelitis&apos;&apos; (OW), &apos;&apos;osteitis but cannot exclude early osteomyelitis&apos;&apos; (OCEO) and &apos;&apos;early osteomyelitis&apos;&apos; (EO). Patient demographics (age, gender) and accessory MRI findings of ulcer and sinus tract depth were recorded. Initial clinical assessment and medical treatment (route and duration of antibiotics), healing versus disease progression and histology or microbiology results were recorded. The isolated marrow T2 signal hyperintensity was reported as OW in 12 patients, OCEO in 18, and EO in 16. No statistical difference in clinical assessment was demonstrated between the OW, OCEO, and EO groups. Pathological condition was available in 15 patients within 0-7 days (mean 2.4 days) of the MRI examination, with 14 (93%) of these positive for osteomyelitis by histopathology or positive cultures. Initial diagnosis of or progression to osteomyelitis was shown in 28 patients (61%). Treatment of suspected osteomyelitis is heavily determined by clinical factors. Patients who initially demonstrate only T2 marrow signal abnormality under a diabetic ulcer are eventually diagnosed as osteomyelitis in 61% of cases and deserve aggressive treatment as early osteomyelitis when meeting clinical parameters. (orig.)

  2. Pulmonary perfusion &apos;&apos;without ventilation&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Chapman, C.N.; Sziklas, J.J.; Spencer, R.P.; Rosenberg, R.J.

    1983-12-01

    An 88-yr-old man, with prior left upper lobectomy and phrenic nerve injury, had a ventilation/perfusion lung image. Both wash-in and equilibrium ventilation images showed no radioactive gas in the left lung. Nevertheless, the left lung was perfused. A similar result was obtained on a repeat study 8 days later. Delayed images, during washout, showed some radioactive gas in the left lung. Nearly absent ventilation (but continued perfusion) of that lung might have been related to altered gas dynamics brought about by the prior lobectomy, a submucosal bronchial lesion, phrenic nerve damage, and limited motion of the left part of the diaphragm. This case raises the issue of the degree of ventilation (and the phase relationship between the lungs) required for the entry of radioactive gas into a diseased lung, and the production of a &apos;&apos;reversed ventilation/perfusion mismatch.&apos;&apos;

  3. The German &apos;'Energiewende'&apos;. Evaluation after the Paris-agreement; Die Deutsche Energiewende. Bewertung nach dem Klima-Abkommen von Paris

    Energy Technology Data Exchange (ETDEWEB)

    Roth, Eike

    2016-08-01

    The World-Climate-Summit 2016 in Paris agreed to exacerbated goals for climate protection. This paper will scrutinize whether Germany can comply with its Paris-obligations by continuing the ongoing German &apos;'Energiewende'&apos;. The result is clear-cut: The German &apos;'Energiewende'&apos; is inadequate. Due to the cap-and-trade system of the EU the &apos;''Energiewende'&apos;.

  4. Internet of &apos;'printed'&apos; Things: low-cost fabrication of autonomous sensing nodes by inkjet printing

    International Nuclear Information System (INIS)

    Kawahara, Yoshihiro

    2014-01-01

    &apos;&apos;What if electronics devices are printed using an inkjet printer even at home?&apos;&apos; &apos;&apos;What if those devices no longer need a battery?&apos;&apos; I will introduce two enabling technologies for the Internet of Things concept. 1. Instant Inkjet Circuits: A low cost, fast and accessible technology to support the rapid prototyping of electronic devices. We demonstrated that &apos;'sintering-free'&apos; silver nano particle ink with a commodity inkjet printer can be used to fabricate printed circuit board and high-frequency applications such as antennas and sensors. The technology is now commercialized by AgIC, Inc. 2. Wireless Power: Although large amounts of data can be exchanged over a wireless communication link, mobile devices are still tethered by power cables. We are trying to solve this problem by two different approaches: energy harvesting. A simple circuitry comprised of diodes and capacitor can convert ambient radio signals into DC current. Our research revealed the signals from TV tower located 6.5km apart could be used to feed 100 microwatts to power microcontrollers

  5. Tratamento microcirúrgico de aneurismas da artéria comunicante anterior

    Directory of Open Access Journals (Sweden)

    Luiz Carlos Mendes Faleiro

    1973-12-01

    Full Text Available Os autores descrevem o tratamento microcirúrgico realizado em oito pacientes que tiveram hemorragia subaracnóidea espontânea por rotura de aneurisma da artéria comunicante anterior. A conduta clínica pré-operatória é apresentada sendo dada ênfase às condições do paciente antes do ato cirúrgico. A técnica cirúrgica é descrita em detalhe, sendo salientado o uso do microscópio binocular. Dos 8 pacientes, dois (25% tinham mais de um aneurisma que foram tratados durante a mesma operação. A única complicação cirúrgica foi meningite pós-operatória em um paciente; esta complicação cedeu completamente ao tratamento. Após a operação 88% dos pacientes retornaram ao seu trabalho, não tendo havido óbito em virtude do tratamento.

  6. Irradiation as a quarantine treatment of &apos;Carabao&apos; (&apos;Manila Super&apos;) mangoes

    International Nuclear Information System (INIS)

    Manoto, E.C.; Resilva, S.S.; Del Rosario, Ma.S.; Casubha, L.C.

    1990-01-01

    Researches using gamma radiation for disinfestation of Oriental fruit fly in &apos;Carabao&apos; (&apos;Manila Super&apos;) mangoes were undertaken using the Probit 9 or 99.9968% mortality test. The results showed that the mature larvae of the fruit fly are the most tolerant stage of this insect to irradiation with the eggs as the most sensitive. On treating more than 100,000 mature larvae in mangoes, a minimum dose of 100 Gy was found to prevent emergence of adult fruit flies and maintain quarantine security or a complete elimination of the possibility of introducing this pest into the importing country. Therefore, the use of 100-Gy irradiation as a quarantine treatment against Oriental fruit fly in the mature green Philippine &apos;carabao&apos; mango fruits is recommended

  7. Progress Report: DE-FG03-97ER20274, &apos;&apos;Microbial Production of Isoprene&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Ray Fall

    2002-03-13

    We have discovered that microorganisms produce and emit the hydrocarbon isoprene (2-methyl-1,3-butadiene), and have suggested that if isoprene-producing enzymes and their genes can be harnessed, useful hydrocarbon-producing systems might be constructed. The main goal of the proposed work is to establish the biochemical mechanism and regulation of isoprene formation in the bacterial system, Bacillus subtilis. Specific objectives of the proposed work are the following: (A) to characterize the physiological regulation of isoprene formation in B. subtilis; (B) to characterize mutations in B. subtilis 168 that suppress isoprene formation, clone these genes, and determine how isoprene and isoprenoid carbon flow are regulated; and (C) to test &apos;'overflow'&apos; and &apos;'signaling'&apos; models for Bacillus isoprene formation. We are also pursuing the isolation and cloning of B. subtilis isoprene synthase, which we believe may be a regulatory enzyme.

  8. The German &apos;'Energiewende'&apos;. Evaluation after the Paris-agreement; Die Deutsche Energiewende. Bewertung nach dem Klima-Abkommen von Paris

    Energy Technology Data Exchange (ETDEWEB)

    Roth, Eike

    2016-12-15

    The World-Climate-Summit 2016 in Paris agreed to exacerbated goals for climate protection. This paper will scrutinize whether Germany can comply with its Paris-obligations by continuing the ongoing German &apos;'Energiewende'&apos;. The result is clear-cut: The German &apos;'Energiewende'&apos; is inadequate. Due to the cap-and-trade system of the EU the &apos;'Energiewende'&apos; can in no way contribute to climate protection.

  9. The &apos;electric power&apos; experience: Between nostalgia and the future. Erlebnis &apos;Strom&apos; zwischen Nostalgie und Zukunft

    Energy Technology Data Exchange (ETDEWEB)

    Moergeli, H.P. (Moergeli und Partner, Muri bei Bern (Switzerland))

    1994-03-04

    The &apos;'Muehleberg'&apos; is a concept which is mostly used in connection with the nuclear power station. But there is more to the &apos;'Muehleberg'&apos; than at first sight. A hydroelectric station, a waste dump gas plant and the brandnew works management centre of the Bernische Kraftwerke AG (BKW) constitute the framework for a host of other attractions in the field of electric power; among others, examples of technological culture in the BKW museum, which are worth seeing. (orig.)

  10. Iran&apos;s &apos;Risk-Taking&apos; in Perspective

    Energy Technology Data Exchange (ETDEWEB)

    Shahram, Chubin

    2008-07-01

    Assessing any state&apos;s intentions is a difficult undertaking - especially at a specific moment in time. When a state is considered hostile, its behaviour erratic, and its system opaque, what is difficult under normal circumstances becomes nearly impossible. It may thus often seem prudent to attribute the worst of intentions to such states, but this can create a self-fulfilling prophecy. Iran with its revolutionary pretensions, fiery rhetoric and nuclear ambitions, is a case in point, since it is particularly difficult to &apos;read&apos;. Located in the centre of a geo-politically sensitive and conflict-driven area, Iran is in a position to influence - positively or otherwise - the Persian Gulf, the Caucasus, the Middle East and South Asia. This influence may furthermore be expanding as a result of the weakening of Iraq and Lebanon, divisions among the Palestinians, and the more general rise of the Shi&apos;i across the broader region. Add to this the ambiguous aims of Iran&apos;s nuclear programme and the shadow this has already thrown across the region, and the need to assess Iran&apos;s intentions accurately appears crucial. Here, Iran&apos;s past behavior may provide some help, especially when it comes to Iran&apos;s proclivity for risk taking - provided the acquisition of a nuclear capability does not alter Iran&apos;s intentions or behavior so as to make the past irrelevant. Some commentators believe that Iran&apos;s ideology and past behaviour suggest that a nuclear-capable Iran will be inclined to take on a high level of risk, without concern for the potential costs of this recklessness, and that Iran may perhaps even welcome the risks involved. By contrast, the recent National Intelligence Estimate (NIE), a composite of US intelligence agency estimates, has concluded that Iran&apos;s &apos;decisions are guided by a cost-benefit approach&apos; and therefore &apos;may be more vulnerable to influence&apos; than they had previously (i.e.2005) judged. These

  11. Qualidade de bulbos de cebola em consequência de tratamentos pré-colheita

    Directory of Open Access Journals (Sweden)

    Ferreira Marcos David

    2000-01-01

    Full Text Available Com o objetivo de se avaliar o efeito de tratamentos pré-colheita na qualidade de bulbos de cebola, através dos parâmetros perda de peso, espessura e coloração da casca, diâmetro e firmeza do bulbo, foi conduzido experimento em Paulínia, Estado de São Paulo, em 1997. Foram utilizados quatro tratamentos: testemunha; oxicloreto de cobre (250 g 100 L-1 de água; ácido bórico (250 g 100 L-1 de água; e a combinação dos dois últimos e seis cultivares: Serrana, Régia, Crioula e três híbridos da SVS, HT, HS-1 e HS-2. Os tratamentos foram aplicados durante a bulbificação. Os bulbos foram armazenados à temperatura ambiente (25ºC e analisados periodicamente para os parâmetros citados. Os resultados permitiram observar que a aplicação pré-colheita do oxicloreto de cobre, nas quatro últimas semanas do ciclo, aumentou significativamente a resistência da casca dos bulbos, reduziu a perda de peso e incrementou a coloração dos mesmos, para todas as cultivares. Cultivares com casca mais escura apresentaram melhor resposta aos tratamentos pré-colheita para a coloração, do que as de casca mais clara. A firmeza dos bulbos, não foi influenciada pelos tratamentos pré-colheita.

  12. Nuclear waste disposal. A wicked and highly conflict bearing societal problem; Nukleare Entsorgung. Ein &apos;'wicked'&apos; und hoechst konfliktbehaftetes Gesellschaftsproblem

    Energy Technology Data Exchange (ETDEWEB)

    Brunnengraeber, Achim; Mez, Lutz [Freie Univ. Berlin (Germany). Forschungszentrum fuer Umweltpolitik; Di Nucci, Maria Rosaria; Schreuers, Miranda [Freie Univ. Berlin (Germany)

    2012-12-15

    The final disposal of nuclear wastes is called &apos;'messy'&apos; or &apos;'wicked'&apos; in the political science literature. The highly complicated problems are characterized by a number of features such as intra- and inter-generational aspects and ethical questions. In the case of stakeholders the differences concern ideologies, interests, merits and preferences that cause conflicts. The search for solutions is complicated due to interacting political, social, ecologic, economic and technical aspects. The concepts &apos;&apos;wicked problems&apos;&apos; and &apos;'multi-level-governance'&apos; are promising approaches to solve the complicated situation.

  13. What do we mean by the word &apos;'Shock'&apos;?

    International Nuclear Information System (INIS)

    Runnels, Scott Robert

    2015-01-01

    From one vantage point, a shock is a continuous but drastic change in state variables that occurs over very small time and length scales. These scales and associated changes in state variables can be measured experimentally. From another vantage point, a shock is a mathematical singularity consisting of instantaneous changes in state variables. This more mathematical view gives rise to analytical solutions to idealized problems. And from a third vantage point, a shock is a structure in a hydrocode prediction. Its width depends on the simulation&apos;s grid resolution and artificial viscosity. These three vantage points can be in conflict when ideas from the associated fields are combined, and yet combining them is an important goal of an integrated modeling program. This presentation explores an example of how models for real materials in the presence of real shocks react to a hydrocode&apos;s numerical shocks of finite width. The presentation will include an introduction to plasticity for the novice, an historical view of plasticity algorithms, a demonstration of how pursuing the meaning of &apos;'shock'&apos; has resulted in hydrocode improvements, and will conclude by answering some of the questions that arise from that pursuit. After the technical part of the presentation, a few slides advertising LANL&apos;s Computational Physics Student Summer Workshop will be shown.

  14. &apos;Green Isle&apos; on the &apos;Red Isle&apos;. The gasometer in Berlin becomes a centre of the &apos;European Energy Forum&apos;; &apos;Gruene Insel&apos; auf der &apos;Roten Insel&apos;. Der Berliner Gasometer wird zum Zentrum des &apos;Europaeischen Energie Forums&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Meyer, Ulf

    2013-06-01

    If the ARD political talk show with Guenther Jauch starts on Sunday night after the crime thriller, only few viewers know that they are tele-guests on the former gasometer site in Berlin-Schoeneberg. Currently, this site is being transformed into an environmentally friendly campus called the &apos;European Energy Forum&apos; (EUREF). According to the will of the owner and architect Reinhard Mueller, the campus will become the largest CO{sub 2} neutral office and business location in Europe. Totally 600 million Euro will be invested. All new buildings should be ecological &apos;green buildings&apos; and received the LEED Gold certification.

  15. Tratamento adjuvante nos GISTs Adjuvant treatment in GISTs

    Directory of Open Access Journals (Sweden)

    Laercio Gomes Lourenço

    2011-09-01

    Full Text Available INTRODUÇÃO: O tumor estromal gastrointestinal (GIST é o sarcoma mais comum do aparelho digestivo. Essa neoplasia ocorre devido à mutação do gene KIT com consequente ativação constitutiva da proteína KIT. O tratamento primário é cirúrgico e consiste na sua ressecção completa. Entretanto, alguns grupos de pacientes apresentam risco elevado de recorrência mesmo após operação com ressecção completa (R0, indicando diferenças no comportamento biológico. Estudos clínicos comprovaram a atividade clínica do mesilato de imatinibe, fazendo dele a primeira linha de tratamento padrão nos GISTs metastáticos ou irressecáveis, mudando muito o desfecho clínico dessa doença em relação aos benefícios anteriormente obtidos com a quimioterapia antineoplásica. MÉTODO: Foi realizada revisão da literatura com consulta nos periódicos das bases Medline/Pubmed, Scielo e Lilacs cruzando os descritores: tumor estromal gastrointestinal, Gist, tratamento, adjuvância. Além desta revisão foi adicionada a experiência pessoal dos autores. CONCLUSÃO: Melhor refinamento dos critérios de prognóstico tem permitido selecionar de forma mais adequada pacientes para o tratamento adjuvante com imatinibe. Os resultados de maior evidência até o momento respaldam o tratamento adjuvante por um ano, o que produz benefício significativo na sobrevida livre de recidiva, mas não na sobrevida global desses pacientes.INTRODUCTION: Gastrointestinal stromal tumor (GIST is the most common sarcoma of the digestive tract. This cancer occurs due to mutation of the KIT gene resulting in constitutive activation of KIT protein. The primary treatment is surgical and consists of complete resection. However, some groups of patients at high risk of recurrence even after surgery with complete resection (R0, indicate differences in biological behavior. Clinical studies have demonstrated the clinical activity of imatinib mesylate, making it the standard first

  16. Design of the fuel element &apos;snow-flake&apos; in uranium oxide, canned with aluminium, for the experimental reactor EL 3 (1960); Etude d&apos;un element combustible en oxyde d&apos;uranium gaine d&apos;aluminium, type &apos;&apos;cristal de neige&apos;&apos; pour la pile EL 3 (1960)

    Energy Technology Data Exchange (ETDEWEB)

    Gauthron, M.; Guibert, B. [Commissariat a l' Energie Atomique, Saclay (France).Centre d' Etudes Nucleaires

    1960-07-01

    This report sums up the main studies have been carried out on the fuel element &apos;Snowflake&apos; (uranium oxide, canned with aluminium), designed to replace the present element of the experimental reactor EL3 in order to increase the reactivity without modifying the neutron flux/thermal power ratio. (author) [French] Ce rapport resume les principales etudes qui ont ete faites sur l&apos;element combustible &apos;Cristal de Neige&apos; (a oxyde d&apos;uranium, gaine d&apos;aluminium) destine a remnlacer l&apos;element actuel du reacteur experimental EL3, afin d&apos;en augmenter la reactivite sans modifier le rapport flux neutronique-puissance thermique. (auteur)

  17. Chamber transport of &apos;'foot'&apos; pulses for heavy-ion fusion

    Energy Technology Data Exchange (ETDEWEB)

    Sharp, W.M.; Callahan-Miller, D.A.; Tabak, M.; Yu, S.S.; Peterson, P.F.

    2002-02-20

    Indirect-drive targets for heavy-ion fusion must initially be heated by &apos;'foot'&apos; pulses that precede the main heating pulses by tens of nanoseconds. These pulses typically have a lower energy and perveance than the main pulses, and the fusion-chamber environment is different from that seen by later pulses. The preliminary particle-in-cell simulations of foot pulses here examine the sensitivity of the beam focusing to ion-beam perveance, background-gas density, and pre-neutralization by a plasma near the chamber entry port.

  18. Development and utilization of a mechanical barrier for large-calibre cavern necks. The &apos;&apos;Spider Plug&apos;&apos;; Entwicklung und Einsatz einer mechanischen Absperrung fuer grosskalibrige Kavernenhaelse. Der &apos;&apos;Spider Plug&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Pfeifer, K.; Maut, D. [UGS GmbH, Mittenwalde (Germany)

    2013-08-01

    An hydraulic separation of a well and the cavern can be necessary for different workover applications, e.g. casing milling or underreaming. The separation is needed to ensure a mud circulation during such operations. In that case a barrier is set after flooding the cavern, which will then be used as a mechanical abutment for the cement bridge. If the diameter of the cavern neck has been enlarged due to e.g. unwanted leaching processes or unstabilized underreaming processes, it might get impossible to set a standard plug with the available technologies into those diameters. Therefore UGS GmbH has developed a mechanical plug, which is set hydraulically. The so called &apos;Spider Plug&apos; is used as basis for a cement bridge and can be removed by drilling after the workover has been done. Depending on the dimension of the setting tool a cavern neck up to 50&apos;&apos; diameter can be plugged by the &apos;Spider Plug&apos;. Up to now a number of successful operations on different locations has shown, that the &apos;Spider Plug&apos; is a practicable and cost-efficient solution for a mechanical abutment of large cavern necks. (orig.)

  19. Three ways to storage solution. &apos;&apos;Lead or Lithium?&apos;&apos;. This is not the only basic issue in a storage system; Drei Wege zur Speicherloesung. &apos;&apos;Blei oder Lithium?&apos;&apos; Dies ist nicht die einzige Grundsatzfrage bei einem Speichersystem

    Energy Technology Data Exchange (ETDEWEB)

    Welter, Philippe; Siemer, Jochen

    2013-06-15

    The number of solar power storage systems offered is now in the hundreds, if one includes all possible product combinations. We show in the following pages a selection of examples of typical solutions, which are by the KfW program &apos;&apos;Renewable Energy - Storage&apos;&apos; eligible&apos;&apos;. With various modifications, they can be divided into three groups: battery inverter with built-in storage, external storage on the DC side of the PV system and stand-alone systems on AC power. [German] Die Zahl der angebotenen Solarstromspeichersysteme geht mittlerweile in die Hunderte, wenn man alle moeglichen Produktkombinationen einbezieht. Wir zeigen auf den folgenden Seiten eine exemplarische Auswahl an typischen Loesungen, die mittels KfW-Programm &apos;&apos;Erneuerbare Energien - Speicher&apos;&apos; foerderfaehig sind. Mit diversen Modifikationen lassen sie sich in drei Gruppen einteilen: Akkuwechselrichter mit integriertem Speicher, externe Speicher an der Gleichstromseite der Photovoltaikanlage und Stand-alone-Systeme am Wechselstromnetz.

  20. Sistema alternativo de tratamento de água em escala descentralizada

    OpenAIRE

    Franco, Camila Silva

    2015-01-01

    A inexistência de um sistema de tratamento e distribuição de água em áreas remotas leva a população ao consumo de água de baixa qualidade, em função das ações antrópicas no nível das bacias hidrográficas. O desenvolvimento de sistemas descentralizados, que contemplem as distâncias entre residências em áreas escassamente povoadas pode proporcionar água potável, de maneira fácil, autossustentável e a baixo custo. Nesse contexto, objetivou-se o desenvolvimento de uma Estação de Tratamento de Águ...

  1. Energy saving retrofitting of a prefabricated panel construction kinder-garden - demonstration project &apos;'Plappersnut'&apos; in Wismar.; Energetische Sanierung einer Kindertagesstaette in Plattenbauweise - Demonstrationsbauvorhaben &apos;'Plappersnut'&apos; in Wismar

    Energy Technology Data Exchange (ETDEWEB)

    Wollensak, Heidi [Institut fuer Gebaeude + Energie + Licht Planung, Alter Holzhafen 19, 23966 Wismar (Germany); Wollensak, Martin [Hochschule Wismar, FG Baukonstruktion und Baustofftechnik (Germany); Roemhild, Thomas [Hochschule Wismar, FG Entwerfen, Gebaeude- Klima- und Lichtplanung (Germany); Mainka, Georg-Wilhelm; Winkler, Heiko [Lehrstuhl fuer Baukonstruktionen und Bauphysik, Institut fuer Bauingenieurwesen, Universitaet Rostock (Germany)

    2005-12-01

    The project &apos;&apos;kindergarten Plappersnut&apos;&apos; in Wismar focuses on cutting the energy consumption of the in 1972 build prefabricated plate construction down to one third by mainly 3 means: - improving the relation between building volume and outside surface by replacing the corridor building between the two main wings with a light membrane roof, covering the whole space, - eliminating energy loss through the building structure by coating the whole building with different isolation systems, - replacing all of the technical installation under the aspects of ecological energy supply and energy retrieving systems. The project was classed as a demonstration project of the EnSan-Program, supported by the German Ministry for Economy and Technology. (Abstract Copyright [2005], Wiley Periodicals, Inc.) [German] Das Sanierungsprojekt der 1972 in Plattenbauweise errichteten Kita &apos;'Plappersnut'&apos; stand im Zeichen der Reduzierung des Energiebedarfs auf ein Drittel durch drei wesentliche Massnahmen: - Verbesserung des Verhaeltnisses Gebaeudevolumen zu Aussenwandflaeche durch Entfernung der Verbindungsgaenge zwischen beiden Gebaeudeteilen und Ueberdachung des entstehenden Hofes mit einem Membrandach, - Verminderung der Energieverluste durch die Gebaeudehuelle mit Hilfe verschiedener Waermedaemm-Massnahmen, - Ersatz der gesamten Gebaeudetechnik durch energiesparende Systeme und unter Einsatz von erneuerbaren Energien. Das Projekt wurde im Rahmen des EnSan-Programms vom Bundesministerium fuer Wirtschaft und Technologie gefoerdert. (Abstract Copyright [2005], Wiley Periodicals, Inc.)

  2. Inorganic profile of some Brazilian medicinal plants obtained from ethanolic extract and &apos;&apos;in natura&apos;&apos; samples

    Energy Technology Data Exchange (ETDEWEB)

    Ferreira, M.O.M.; de Sousa, P.T.; Salvador, V.L.R.; Sato, I.M.

    2004-10-03

    The Anadenathera macrocarpa, Schinus molle, Hymenaea courbaril, Cariniana legalis, Solidago microglossa and Stryphnodendron barbatiman, were collected &apos;&apos;in natura&apos;&apos; samples (leaves, flowers, barks and seeds) from different commercial suppliers. The pharmaco-active compounds in ethanolic extracts had been made by the Mato Grosso Federal University (UFMT). The energy-dispersive x-ray fluorescence (ED-XRF) spectrometry was used for the elemental analysis in different parts of the plants and respective ethanolic extracts. The Ca, Cl, Cu, Fe, K, Mg, Mn, Na, Ni, P, Rb, S, Sr and Zn concentrations were determined by the fundamental parameters method. Some specimens showed a similar inorganic profile for &apos;&apos;in natura&apos;&apos; and ethanolic extract samples and some ones showed a distinct inorganic profile. For example, the Anadenathera macrocarpa showed a similar concentration in Mg, P, Cu, Zn and Rb elements in &apos;&apos;in natura&apos;&apos; and ethanolic extract samples; however very different concentration in Na, S, Cl, K , Ca, Mn, Fe and Sr was observed in distinctive samples. The Solidago microglossa showed the K, Ca, Cl, S, Mg, P and Fe elements as major constituents in both samples, suggesting that the extraction process did not affect in a considerable way the &apos;&apos;in natura&apos;&apos; inorganic composition. The elemental composition of the different parts of the plants (leaves, flowers, barks and seeds) has been also determined. For example, the Schinus molle specimen showed P, K, Cl and Ca elements as major constituents in the seeds, Mg, K and Sr in the barks and Mg, S, Cl and Mn in the leaves, demonstrating a differentiated elementary distribution. These inorganic profiles will contribute to evaluate the quality control of the Brazilian herbaceous trade and also will assist to identify which parts of the medicinal plants has greater therapeutic effect.

  3. Eletroacupuntura para tratamento de hipotensão induzida por isofluorano em cavalos

    Directory of Open Access Journals (Sweden)

    E.C. Franco

    2014-04-01

    Full Text Available Objetivou-se avaliar a eficiência do tratamento da hipotensão arterial com eletroacupuntura comparativamente à dobutamina em equinos. Foram avaliados seis cavalos adultos, saudáveis, mantidos em anestesia inalatória, com isofluorano, em ventilação mecânica. Após a estabilização da anestesia, foi induzida hipotensão arterial, através do incremento da concentração do isofluorano, iniciando-se um dos tratamentos: DOB: dobutamina (1,5µg kg-1 min-1, infusão contínua intravenosa; EA: estímulo elétrico no acuponto pericárdio 6 (PC6, bilateralmente; SHAM: estímulo elétrico em ponto falso de acupuntura. Foram mensurados: frequência cardíaca (FC, pressão arterial média (PAM, temperatura retal (T, concentração final expirada de isofluorano (ETiso, variáveis hemogasométricas, concentração sérica de aspartato aminotransferase (AST e creatina fosfoquinase (CK, tempo e qualidade da recuperação pós-anestésica. Houve incremento na PAM de 50%, 36,6% e 7,5% nos tratamentos DOB, EA e SHAM, respectivamente. Não houve diferença entre os grupos nas variáveis hemogasométricas, FC, T, ETiso, CK, AST, tempo e qualidade de recuperação pós-anestésica. Conclui-se que o tratamento com dobutamina foi mais efetivo para o tratamento da hipotensão em cavalos sob anestesia inalatória quando comparado ao estímulo elétrico do acuponto PC6 ou ponto falso de acupuntura.

  4. Avaliação e tratamento da hiperglicemia em pacientes graves

    Directory of Open Access Journals (Sweden)

    Marina Verçoza Viana

    2014-03-01

    Full Text Available A hiperglicemia é um problema frequentemente encontrado em pacientes graves em ambiente de terapia intensiva. Sua presença se associa ao aumento da morbidade e da mortalidade, independentemente da causa da admissão (infarto agudo do miocárdio, condição após cirurgia cardiovascular, acidente vascular cerebral e sepse. Entretanto, permanecem muitas dúvidas com relação à fisiopatologia e, particularmente, em relação ao tratamento da hiperglicemia no paciente graves. Na prática clínica, devem ser levados em consideração diversos aspectos para o controle desses pacientes, inclusive os alvos de glicemia, o histórico de diabetes mellitus, a via de nutrição (enteral ou parenteral e o equipamento de monitoramento disponível, o que aumenta substancialmente a carga de trabalho dos profissionais envolvidos nesse tratamento. Esta revisão descreveu a epidemiologia, a fisiopatologia, o tratamento e o monitoramento da hiperglicemia no paciente adulto grave.

  5. Proceedings of the DGMK-conference &apos;Synthesis gas chemistry&apos;. Authors&apos; manuscripts

    Energy Technology Data Exchange (ETDEWEB)

    Hoenicke, D.; Kohlpaintner, C.; Luecke, B.; Reschetilowski, W. [eds.

    2000-07-01

    The main topics of the DGMK-Conference &apos;&apos;Synthesis Gas Chemistry&apos;&apos; were: production of synthesis gas from several educts, new catalysts, Fischer-Tropsch synthesis, hydroformylation, steam reforming and carbonylation.

  6. Improvement in remote sensing of low vegetation cover in arid regions by correcting vegetation indices for soil &apos;'noise'&apos;

    International Nuclear Information System (INIS)

    Escadafal, R.; Huete, A.

    1991-01-01

    The variations of near-infrared red reflectance ratios of ten aridic soil samples were correlated with a &apos;&apos;redness index&apos;&apos; computed from red and green spectral bands. These variations have been shown to limit the performances of vegetation indices (NDVI and SAVI) in discriminating low vegetation covers. The redness index is used to adjust for this &apos;&apos;soil noise&apos;&apos;. Dala simulated for vegetation densities of 5 to 15% cover showed that the sensitivity of the corrected vegetation indices was significantly improved. Specifically, the &apos;'noise-corrected'&apos; SAVI was able to assess vegetation amounts with an error four times smaller than the uncorrected NDVI. These promising results should lead to a significant improvement in assessing biomass in arid lands from remotely sensed data. (author) [fr

  7. Les Houches &apos;&apos;Physics at TeV Colliders 2003&apos;&apos; Beyond the Standard Model Working Group: Summary Report

    Energy Technology Data Exchange (ETDEWEB)

    Allanach, B

    2004-03-01

    The work contained herein constitutes a report of the &apos;&apos;Beyond the Standard Model&apos;&apos; working group for the Workshop &apos;&apos;Physics at TeV Colliders&apos;&apos;, Les Houches, France, 26 May-6 June, 2003. The research presented is original, and was performed specifically for the workshop. Tools for calculations in the minimal supersymmetric standard model are presented, including a comparison of the dark matter relic density predicted by public codes. Reconstruction of supersymmetric particle masses at the LHC and a future linear collider facility is examined. Less orthodox supersymmetric signals such as non-pointing photons and R-parity violating signals are studied. Features of extra dimensional models are examined next, including measurement strategies for radions and Higgs&apos;, as well as the virtual effects of Kaluza Klein modes of gluons. Finally, there is an update on LHC Z&apos; studies.

  8. Biological effect and tumor risk of diagnostic x-rays. The &apos;&apos;war of the theories&apos;&apos;; Biologische Wirkung und Tumorrisiko diagnostischer Roentgenstrahlen. Der &apos;&apos;Krieg der Modelle&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Selzer, E.; Hebar, A. [Medizinische Universitaet Wien, Abteilung fuer Strahlenbiologie, Klinik fuer Strahlentherapie, Wien (Austria)

    2012-10-15

    Since the introduction of ionizing radiation as a treatment and diagnostic tool in humans, scientists have been trying to estimate its side effects and potential health risks. There is now ample evidence for the principal existence of a direct relationship between higher doses and the risks of side effects. Most of the uncertainties lie in the field of low-dose effects especially with respect to the risk of cancer induction. Low-dose effects are usually of relevance in diagnostic medicine while high-dose radiation effects are typically observed after radiotherapeutic treatment for cancer or after nuclear accidents. The current state of the &apos;&apos;war of theories&apos;&apos; may be summarized as follows: one group of scientists and health regulatory officials favors the hypothesis that there is no threshold dose, i.e. the linear-no-threshold hypothesis (LNT) of radiation which can be regarded as safe. On the contrary, the critics of this hypothesis suggest that the risks of doses below 50 mSv are not measurable or even of clinical relevance and are not adequately described by a linear dose-response relationship. The aim of this article is to summarize the major unresolved issues in this field. Arguments are presented why the validity of the LNT model in the low-dose range should be regarded as at least inconsistent and is thus questionable. (orig.) [German] Seit der Einfuehrung ionisierender Strahlen als ein Mittel zur Behandlung und Diagnose beim Menschen haben Wissenschaftler versucht, ihre Nebenwirkungen und potenziellen Risiken fuer die Gesundheit einzuschaetzen. Es gibt nun ausreichende Evidenz fuer das grundsaetzliche Vorliegen einer direkten Beziehung zwischen hoeheren Dosen und Nebenwirkungsrisiken. Die meisten Unsicherheiten liegen auf dem Gebiet der Niedrigdosisforschung v. a. im Hinblick auf das Risiko der Induktion von Krebs. Niedrigdosiseffekte sind ueblicherweise von Bedeutung in der diagnostischen Medizin, waehrend Hochdosisbestrahlungseffekte

  9. Functional and morphological parameters with tissue characterization of cardiovascular magnetic imaging in clinically verified &apos;&apos;infarct-like myocarditis&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Schwab, Johannes [Paracelsus Medical Univ., General Hospital Nuremberg (Germany). Dept. of Cardiology and Radiology; Rogg, H.J.; Pauschinger, M.; Fessele, K. [Paracelsus Medical Univ., General Hospital Nuremberg (Germany). Dept. of Cardiology; Bareiter, T.; Baer, I. [Paracelsus Medical Univ., General Hospital Nuremberg (Germany). Dept. of Cardiology and Neuroradiology; Loose, R. [Paracelsus Medical Univ., General Hospital Nuremberg (Germany). Dept. of Radiology

    2016-04-15

    Cardiac magnetic resonance (CMR) has increasingly proved to be a valuable diagnostic tool for evaluating patients with suspected myocarditis. The objective of this study was to evaluate the diagnostic value of functional and morphological parameters including tissue characterization in patients with &apos;&apos;infarct-like myocarditis&apos;&apos;. 43 patients with clinically verified cases of &apos;&apos;infarct-like myocarditis&apos;&apos; (median time to MRI scanning after admission for acute symptoms 3 days) and 35 control patients matched by age and sex were included in this retrospective case control study. In this study we used a 1.5 T MRI scanner conducting steady-state-free-precession sequences, T2-weighted imaging, T1-weighted imaging before and after contrast administration and late gadolinium enhancement sequences. According to the recommendations for CMR diagnosis of myocarditis (Lake Louise consensus criteria), a scan was positive for acute myocarditis if 2 of 3 CMR criteria were present. 30 % of the patients with &apos;&apos;infarct-like myocarditis&apos;&apos; had a reduced left ventricular ejection fraction, 11 % had an increased LV end-diastolic volume index and 35 % had an increased LV mass index. The sensitivity of wall motion abnormalities was 63 % with a regional distribution in 49 %. In 47 % of cases regional wall motion abnormalities were present in the lateral left ventricular segments. Pericardial effusions were discovered in 65 % of cases with a circular appearance in 21 % and focal manifestation in 44 %. The diagnostic sensitivity, specificity, and accuracy of CMR in patients with &apos;&apos;infarct-like myocarditis&apos;&apos; were 67 %, 100 % and 82 %, respectively. The LGE alone was the most sensitive test parameter with 86 %, providing a specificity of 100 % and accuracy of 92 %. Our study results can be applied to the subgroup of patients with &apos;&apos;infarct-like myocarditis&apos;&apos;, where we found that LGE alone was the

  10. Design Concept of a Seal-off Type 14 MeV Neutron Generator of 10&apos;&apos;1&apos;&apos;1n/s Range

    Energy Technology Data Exchange (ETDEWEB)

    In, S. R.; Oh, B. H. [KAERI, Daejeon (Korea, Republic of)

    2015-05-15

    The total neutron fluence during the life time is expected to be around 10MW·yr/m&apos;&apos;2 which may cause a damage of -100 dpa in materials. To estimate the adaptability of candidate materials in a few years, a 14MeV neutron source with a flux level of 3 - 5 x 10&apos;&apos;1&apos;&apos;8 n/s·m&apos;&apos;2, which is the goal of the IFMIF facility costing more than ¤1000M, is necessitated. The problem in making an intense neutron generator of beam target type is really not on the neutron production rate, but on the huge heat generated in the target, because the fusion power is only one of thousands of beam power exerted on the target. We have a plan to develop neutron generators step by step from a 10&apos;&apos;8 n/s level. The final goal is establishing a 14MeV neutron irradiation facility at 10&apos;&apos;1&apos;&apos;4 intensity level.. Up to the 10&apos;&apos;1&apos;&apos;0 n/s level, there occurs basically no critical thermal problem, because beam power density is in the range of tens W/cm&apos;&apos;2. The neutron generator designed in a sealed-off type because of tritium safety is mainly composed of an ion source, target, reaction chamber, and getter pump.. The major design concepts for the neutron generator with the neutron production rate of 10&apos;&apos;1&apos;&apos;1 n/s range were presented. The specifications of the ion source, target and getter have been determined for attaining the goal of the neutron generation rate.

  11. QUALIDADE DE GOIABAS ‘PEDRO SATO’ EM FUNÇÃO DE TRATAMENTOS ALTERNATIVOS EM PÓS-COLHEITA

    Directory of Open Access Journals (Sweden)

    MARIA CECÍLIA DE ARRUDA PALHARINI

    2016-02-01

    Full Text Available RESUMO Este trabalho teve como objetivo avaliar o efeito de produtos alternativos e termoterapia, isoladamente e em associação, na qualidade físico-química e no controle das podridões de goiabas ‘Pedro Sato’. Inicialmente, foi avaliado o efeito dos tratamentos em pós-colheita com cloreto de cálcio, fosfito de potássio, 1-metilciclopropeno (1-MCP, fécula de mandioca, etanol seguido de cloro (etanol+cloro e termoterapia, durante oito dias de armazenamento dos frutos a 22ºC. Em uma segunda etapa, quatro tratamentos foram selecionados (fécula de mandioca, 1-MCP, termoterapia e etanol+cloro e avaliados em associação de dois, aplicados de forma sequencial, durante oito dias de armazenamento dos frutos a 25ºC. Os tratamentos 1-MCP e fécula foram os mais eficazes em manter a qualidade físico-química das goiabas ‘Pedro Sato’, retardando a perda de massa, a mudança de coloração da casca e contribuindo para a retenção da firmeza. Constatou-se maior redução de frutos com podridão nos tratamentos com termoterapia, fécula de mandioca e 1-MCP. As associações de tratamento com 1-MCP/fécula de mandioca e termoterapia/fécula foram os tratamentos mais eficazes em manter a qualidade das goiabas ‘Pedro Sato’, retardando a perda de massa, a mudança de coloração da casca e a redução da firmeza. As associações de tratamento reduziram a ocorrência de podridões, com destaque para os tratamentos com etanol+cloro/termoterapia e termoterapia/fécula, que foram mais eficientes até o quarto dia de armazenamento. Observou-se correlação entre a incidência de podridões e os parâmetros cor da casca e firmeza da polpa para a maioria das associações de tratamentos. De maneira geral, recomenda-se o tratamento com termoterapia/fécula para goiabas armazenadas a 22-25ºC, como forma de manutenção da qualidade físico-química e atrasando em, pelo menos, dois dias os sintomas de podridões.

  12. NDA National Graduate Programme &apos;nucleargraduates&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Dawson, Carl

    2010-07-01

    The aim of this paper is to outline the NDA National Graduate Programme (nuclear graduates). The NDA has a remit under the Energy Act (2004) &apos;to maintain and develop the skills for decommissioning and nuclear clean-up&apos;. Although current research is now being reviewed, there is significant evidence to suggest that the age profile in the Site Licence Companies is skewed towards older workers and there is likely to be a skill shortage in 3-5 years. As nuclear clean-up is a national issue; skill shortages also become a national issue in a very real sense. In addition, evidence suggests that the industry needs to be constantly challenged in order to achieve its targets for decommissioning. The NDA has a unique position under the Act. It is both a strategic overseer and direct employer. To this end the &apos;National Graduate Programme&apos; is aligned to both the NDA&apos;s previous succession plans and the needs of the industry. Industry needs leadership that challenges the status quo and moves the UK nuclear industry to become best in class; Industry needs a dedicated to programme to address skills shortages and difficult to recruit areas such as, but not exclusively, estimators, schedulers, contract managers, site engineers, decommissioning technicians, safety monitors; The NDA has indicated a &apos;commercial and politically savvy&apos; cohort is required to meet its own internal challenges and to ensure sustainability in its own workforce, and to be sensitive to the needs of customers and suppliers alike; Need to create a more diversified workforce in the nuclear industry and also plan for new skills evolving from research and development breakthroughs; Need to ensure that Tier 1, 2, 3 and 4 contractors invest in the leadership and skills for the future. World Class - delivery will be benchmarked against UK based multinational companies who operate in a global graduate attraction and development marketplace. The graduates targeted will be from leading

  13. &apos;Modernization property&apos; of our country is visualized / TAISEI; Wagakuni no &apos;kindaika isan&apos; wo eizoka / taiseisensetsu

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-11-10

    TAISEI was about rapidly promoted from Days of the Tokugawa shogunate over Meiji and Taisho this, and the documentary film which focused on building and &apos;the modernization property&apos; which are related to industry and traffic and civil engineering which made the base of the our country development was planned and was produced. The title of the movie is &apos;travel to the Japan modernization property&apos;. The movie which really introduced such modern age property is rare, and it s as an image material precious. It tries to pick up main thing, The oldest lighthouse &apos;Mikomotojima Island lighthouse (Shizuoka Prefect.1870)&apos; and covers Shiga Prefecture and Kyoto prefecture,&apos;The Lake Biwa hydrophobic&apos;, in our country, the first gravitational concrete dam &apos;Nunobiki Gohnmatsu dam, Kobe City, 1900&apos;Length furnace for the cement baking which remains in Yamaguchi Prefect. &apos;The ONODA CEMENT (Pacific Ocean cement) sake bottle furnace&apos;. In becoming modernization property which widely remains in our country and so on the guide person, Mr. Shinbo Minami of the illustrator has introduced it. The narration is the Mr. platform step of the actress. Still, screening party of this movie is done in the following schedule (admission free). The detailed query is Japanese movie new Co. (141-0021 2-10-17 Kami-Osaki, Shinagawa ku, Tokyo), TEL 03-3442-7251 FAX 03-3442-7360. (translated by NEDO)

  14. Criteria of transformation of object &apos;'Ukryttya'&apos; in environmentally safe system

    International Nuclear Information System (INIS)

    Batyij, V.G.; Jegorov, V.V.; Rud'ko, V.M.; Shcherbyin, V.M.

    2015-01-01

    The analysis of criteria of division of radioactive wastes (RAW) of object &apos;'Ukryttya'&apos; is executed on short-lived and long-lived, and their activity. It is shown that to short-lived RAW underactive belong and insignificant part of me-dium-activity waste. Hundreds of thousands of m3 of RAW on overhead marks belong to long-lived medium-activity wastes. Organization of burial place of such wastes in stable geological structures is an unrealistic task. It is suggested to create the special depository for such RAW, and buried in stable geological structures high-activity wastes only

  15. From the &apos;PCR&apos; function to the &apos;PCR&apos; profession; de la fonction &apos;PCR&apos; au metier &apos;PCR&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Perrin, L. [CERAP, 91 - Gif sur Yvette (France)

    2008-07-01

    After having recalled the legal context concerning the appointment and training of a radiation protection expert (PCR for &apos;personne competente en radioprotection&apos;), the author outlines that the PCR&apos;s role has notably evolved: his function is now of primary importance in the company and his activity does not correspond to the legal framework any longer. Moreover, with the application of a European directive, some small establishments possessing ionizing radiation sources are disadvantaged, and the PCR is now facing an increasing number of missions and tasks. The author gives a list of them and assesses a needed time of 146 days per year: this means PCRs cannot have an other activity within their company

  16. The best selled car. &apos;'Twizy'&apos; leads the sales statistics of electrically powered vehicles - a test report; Der Meistverkaufte. Renaults &apos;'Twizy'&apos; fuehrt die E-Mobil-Verkaufsstatistik an - ein Fahrbericht

    Energy Technology Data Exchange (ETDEWEB)

    Welter, Philippe

    2013-02-15

    Four wheels, two seats, one steering wheel: What does it require more for a small, electrically powered city car? Nothing, says the manufacturer. Two side windows, that is our opinion. With a maximum speed of 80 kilometers per hour and a range of 100 kilometers, the vehicle is certainly ideal for many applications over short distances in the city. PHOTON now uses the &apos;'Twizy'&apos; for almost a year, and gained consistently good experiences.

  17. Fatores de risco cardiovascular em alcoolistas em tratamento

    Directory of Open Access Journals (Sweden)

    Mayla Cardoso Fernandes Toffolo

    2013-06-01

    Full Text Available OBJETIVO: Avaliar a presença de fatores de risco cardiovascular, com ênfase na hipertensão e na adiposidade corporal, em alcoolistas abstinentes ou não abstinentes em tratamento. MÉTODO: Trata-se de um estudo transversal com 65 pacientes alcoolistas em tratamento no CAP-Sad. O grau de dependência do álcool foi avaliado pelo SADD (Short Alcohol Dependence Data e o uso de outras drogas, pelo ASSIST (Alcohol Smoking and Substance Involvement Screening Test. Foram avaliados o perfil bioquímico e o antropométrico dos usuários. RESULTADOS: Participaram do estudo 42 homens e 23 mulheres. A maioria dos participantes (67,74% apresentou dependência alcoólica grave, com uso de álcool associado principalmente a cigarro (66,15%. A média da circunferência da cintura (CC foi significativamente maior entre os abstinentes, em comparação aos não abstinentes (AB: 88,15 ± 15,95 x NA: 81,04 ± 9,86; p = 0,03. Pacientes abstinentes há mais tempo tiveram maior sobrepeso/obesidade e adiposidade abdominal (CC do que os não abstinentes e abstinentes recentes, com razão de chances de 5,25. Os abstinentes apresentaram razão de chances de 3,38 para %GC acima da média, independente do tempo de abstinência. CONCLUSÃO: Pacientes alcoolistas abstinentes apresentam mais sobrepeso/ obesidade, adiposidade corporal (%GC e abdominal (CC do que os não abstinentes. É importante o acompanhamento multiprofissional no tratamento de alcoolistas com abordagem para fatores de risco cardiovasculares, principalmente evitando o ganho de peso.

  18. The &apos;&apos;rising bubble&apos;&apos; sign: a new aid in the diagnosis of unicameral bone cysts

    Energy Technology Data Exchange (ETDEWEB)

    Jordanov, Martin I. [Vanderbilt University Medical Center, Department of Radiology and Radiological Sciences, Nashville, TN (United States)

    2009-06-15

    The observation of a bubble of gas at the most non-dependent margin of a lytic bone lesion which has sustained a pathologic fracture implies that the lesion is hollow and can assist the radiologist in making the diagnosis of a unicameral bone cyst. The imaging studies of two patients who sustained pathologic fractures through unicameral bone cysts and exhibited the &apos;&apos;rising bubble&apos;&apos; sign are shown. The sign&apos;s basis, proper utilization, and potential pitfalls are discussed. (orig.)

  19. Tegretol no tratamento da epilepsia

    Directory of Open Access Journals (Sweden)

    Jorge Armbrust-Figueiredo

    1968-09-01

    Full Text Available O Tegretol (5-carbamil-5H-dibenzo-b,L-azepina foi usado no tratamento de 68 pacientes com epilepsia; 54 apresentavam epilepsia temporal (42 com crises psicomotoras e 12 com crises complexas, 11 epilepsia focal de projeção não temporal e 3 epilepsia centrencefálica com crises P.M. Resultados satisfatórios foram observados em 82% dos 65 pacientes com epilepsia focal; os 3 pacientes com crises P.M. não foram influenciados pelo tratamento. A ação sobre as manifestações psíquicas que acompanhavam o quadro crítico ou intercrítico das crises ficou bem evidenciada. Os pacientes melhoraram de seus sintomas na grande maioria dos casos, conseguindo adaptar-se melhor no ambiente familiar, profissional e escolar. O efeito sobre as alterações eletrencefalográficas é moderado, e a evolução clínica não acompanha as modificações dos traçados. As doses usadas, em geral de 400 a 600 mg diários, são suficientes para o controle das crises na maioria dos casos e estão muito abaixo dos limites considerados como de segurança. As reações secundárias foram observadas em pequeno número de casos e foram sempre transitórias. O Tegretol representa, em nossa opinião, recurso de valor no trataemnto das epilepsias focais, particularmente nas crises psicomotoras.

  20. Maintain levels of nicotine but reduce other smoke constituents: a formula for &apos;'less-hazardous'&apos; cigarettes

    Energy Technology Data Exchange (ETDEWEB)

    Robinson, J.C.; Young, J.C.; Rickert, W.S.

    1984-09-01

    Twenty-two volunteers who smoked more than 20 cigarettes with &apos;'high'&apos; nicotine yields (0.8 to 1.2 mg) per day participated in an 8-week study designed to test the hypothesis that smoking cigarettes with a constant level of nicotine but reduced deliveries of tar, carbon monoxide, and hydrogen cyanide leads to a decrease in smoke absorption. All subjects smoked their usual high-nicotine brand for the first 3 weeks (P1), and the absorption of smoke constituents was determined from levels of thiocyanate and cotinine in saliva and serum, levels of carbon monoxide in expired air, and levels of carboxyhemoglobin in the blood. During the final 5 weeks (P2), the treatment group (16 subjects) switched to the &apos;'light'&apos; version of their usual brands (similar yields of nicotine but with reduced yields of tar, carbon monoxide, and hydrogen cyanide); the control group (6 subjects) smoked their usual brands for the duration of the study. Average levels of cotinine for the subjects who switched during P2 were not significantly different from those of the control group as was expected. Slight reductions were noted in average expired-air carbon monoxide levels, blood carboxyhemoglobin, and saliva thiocyanate, but these reductions were smaller than anticipated based on brand characteristics. The results suggest that the ratio of smoke constituents is different when individuals, rather than machines, smoke cigarettes. Yields determined under subject-defined conditions are necessary in order to properly evaluate the role of nicotine in the design of &apos;'less-hazardous'&apos; cigarettes.

  1. O tratamento da distonia tarefa-específica em músicos: aspectos motores e sensoriais envolvidos no processo

    Directory of Open Access Journals (Sweden)

    Rita de Cássia dos Reis Moura

    2016-03-01

    Full Text Available A distonia é uma desordem de ordem neurológica, caracterizada por descontrole dos movimentos ou de posturas ou ambos, por contração intermitente ou de forma sustentada. A distonia do músico é considerada como uma distonia tarefa-específica, que é deflagrada somente durante a performance musical. Pode ocorrer em qualquer parte do corpo; frequentemente face, músculos do pescoço e membros superiores. O conhecimento dessa doença ocupacional entre a população de músicos no Brasil é pouco difundido. O objetivo deste trabalho é discorrer a respeito das estruturas cerebrais envolvidas no processo motor e da fisiologia envolvida na distonia do músico, bem como dos tratamentos disponíveis no intuito de enfatizar a importância de seu reconhecimento e tratamento precoce e apresentar pesquisa realizada com protocolo de tratamento. O método é um levantamento bibliográfico da fisiologia do controle motor, do desenvolvimento e tratamento da distonia do músico utilizando literatura nacional e internacional e aplicação de protocolo de tratamento estruturado. Como resultados, existe já um corpus bibliográfico consistente na língua inglesa, porém escasso em português, principalmente no quesito tratamento, podemos constatar melhora em diversos aspectos de padrão motor após protocolo de tratamento na avaliação após seis meses, tais como relaxamento, aquisição de maior consciência corporal ao tocar, instabilidade, tremor e dissociação de movimentos. Como conclusão, constata-se a necessidade de implementar a discussão e pesquisa nessa área, principalmente com relação aos tratamentos. Por outro lado, sabe-se que a melhor ferramenta contra esta afecção se encontra no tratamento mais precoce possível.

  2. Tratamento das cefaléias Treatment of headaches

    Directory of Open Access Journals (Sweden)

    José Luiz Dias Gherpelli

    2002-08-01

    Full Text Available Objetivo: realizar revisão bibliográfica sobre o tema tratamento da cefaléia na infância e adolescência. Fontes dos dados: revisão bibliográfica através do banco de dados Medline, utilizando os termos: cefaléia, enxaqueca ou migrânea, infância ou adolescência e tratamento, no período de 1966 a 2001, excluindo artigos de revisão e registros de casos. Foram selecionados artigos científicos que relataram estudos sobre a eficácia da terapêutica farmacológica e não farmacológica no tratamento das cefaléias primárias. Síntese dos dados: foram encontrados 104 artigos científicos, sendo selecionados aqueles que relataram estudos do tipo caso-controle, ou droga versus placebo, cegos ou abertos, e que estudassem crianças ou adolescentes. Conclusões: é digna de nota a pobreza de estudos controlados sobre o tema na faixa etária pediátrica, apesar da importância que as cefaléias primárias apresentam na prática clínica. Apenas algumas drogas foram estudadas de forma cientificamente adequada e, mesmo assim, o número de estudos é pequeno. Tanto o tratamento da crise álgica aguda quanto a profilaxia da cefaléia foram abordados.Objective: to perform a bibliographic review about headache treatment in childhood and adolescence. Sources: articles were searched through Medline database using the terms: migraine, or headache, childhood, or adolescence, and treatment, during the period between 1966 and 2001. Review articles and case reports were excluded. Only articles dealing with pharmacological, and non-pharmacological treatment of primary headaches were selected. Summary of the findings: a total of 104 articles were found; only those reporting results of the case-control studies, or drug vs. placebo, either blind, or open, and that included children, or adolescents were selected. Conclusions: only a few controlled studies about the headache treatment were found in the pediatric age group, although primary headaches are

  3. The &apos;diester partners&apos; want to be movers...; Les &apos;&apos;partenaires diester&apos;&apos; se veulent moteur...

    Energy Technology Data Exchange (ETDEWEB)

    Tourneur, J.C.

    2003-09-01

    Diester is the French name given to the biofuel (methylic ester) made from vegetal oils (1 t of vegetal oil + 0.1 t of methanol leads to 1 t of diester + 0.1 t of glycerin). The French club of &apos;diester towns&apos; gathers all local authorities of towns that use up to 30% of diester in the diesel fuel of their vehicle fleets (buses, trucks, commercial vehicles). In March 2003, the association has opened to new members, in particular private companies which are diester users and become &apos;diester partners&apos;, in order to sustain the fight against the greenhouse effect. The consumption of 1 t of diester allows to save 2.5 t of CO{sub 2} thanks to the photosynthesis. In other words, a vehicle fueled with 30% of diester and 70% of diesel fuel reduces its greenhouse gas emissions of 23%. (J.S.)

  4. Divertículo faringoesofagiano: avaliação dos resultados do tratamento

    Directory of Open Access Journals (Sweden)

    Maria Aparecida Coelho de Arruda Henry

    Full Text Available OBJETIVO: Avaliar a evolução pós-operatória de pacientes com divertículo faringoesofagiano submetidos aos tratamentos cirúrgico e endoscópico. MÉTODOS: Foram analisados de maneira retrospectiva 36 pacientes com divertículo faringo-esofagiano atendidos no Hospital das Clínicas da Faculdade de Medicina de Botucatu - UNESP. Os pacientes foram distribuídos em dois grupos, na dependência do tratamento: grupo 1 (n=24 - diverticulectomia associada á miotomia do cricofaríngeo, através de cervicotomia esquerda; grupo 2 (n=12 - diverticulostomia endoscópica usando grampeador linear. RESULTADOS: A mortalidade operatória foi nula em ambos os grupos. Complicações precoces: grupo 1 - dois pacientes desenvolveram fistula cervical e outros dois, rouquidão; grupo 2 - sem complicações. Complicações tardias: grupo 1 - sem complicações: grupo 2: recidiva da disfagia em quatro pacientes (p=0,01. O seguimento médio foi 33 meses para o grupo 1 e 28 meses para o grupo 2. CONCLUSÃO: Os dois procedimentos foram eficazes na remissão da disfagia. O tratamento cirúrgico apresentou superioridade em relação ao endoscópico, com resolução da disfagia com um único procedimento. O tratamento endoscópico deve ser reservado para os mais idosos e portadores de comorbidades.

  5. A influência do laboratório no tratamento da ceratite infecciosa

    Directory of Open Access Journals (Sweden)

    Flávia Pelinsari Lana

    2011-06-01

    Full Text Available OBJETIVO: Avaliar a resposta terapêutica das ceratites infecciosas e sua correlação com o resultado laboratorial. MÉTODOS: Foram estudados 62 casos retrospectivamente de ceratite infecciosa de moderada à grave, atendidos no Hospitaldo Servidor Público Estadual de São Paulo no período de janeiro de 2000 a dezembro de 2006. Foi avaliada a resposta ao tratamento tópico com colírios antibióticos (Cefalotina 50mg/ml e Gentamicina 14mg/ml ou Ciprofloxacino 0,3%, verificando-se a necessidade de modificação da terapêutica inicial de acordo com a evolução clínica e correlação com os testes microbiológicos pré-tratamento. RESULTADOS: Observou-se que 21 culturas (33,9% foram positivas e 41 (66,1% foram negativas. Houve crescimento de fungo em uma amostra (1,6%. Em apenas dois casos (3,5% houve correlação do exame bacterioscópico com o da cultura. Em 5 casos (8,1% houve necessidade de modificação da medicação devido à piora clínica e 91,9% dos pacientes cursaram com cura do processo infeccioso com o tratamento inicial instituído. CONCLUSÃO: O uso tópico de antibióticos fortificados ou quinolonas foi eficaz no tratamento das ceratites de provável etiologia infecciosa com culturas positivas e negativas.

  6. The energy and monetary implications of the &apos;24/7&apos; &apos;always on&apos; society

    Energy Technology Data Exchange (ETDEWEB)

    Loveday, Dennis L. [Department of Civil and Building Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU (United Kingdom)], E-mail: d.l.loveday@lboro.ac.uk; Bhamra, T.; Tang, T. [Department of Design and Technology, Loughborough University, Loughborough, Leicestershire LE11 3TU (United Kingdom); Haines, V.J.A. [Ergonomics and Safety Research Institute (ESRI), Loughborough University, Loughborough, Leicestershire LE11 3TU (United Kingdom); Holmes, M.J. [ARUP, 13, Fitzroy Street, London W1T 4BR (United Kingdom); Green, R.J. [Institute for Energy Research and Policy, University of Birmingham, Edgbaston, Birmingham B15 2TT (United Kingdom)

    2008-12-15

    This paper reviews the trends in society, technology and energy demand of the past 30 years, together with the growth of the &apos;on-demand&apos; culture. The &apos;24/7&apos; or &apos;always on&apos; society can be defined as one where people demand-and generally receive-what they want &apos;now&apos;. It has grown up in parallel with developments in information technology, which have produced the services needed to meet that demand. Larger numbers of appliances, resulting from greater affluence and disposable income, have increased energy use, despite energy efficiencies in other areas. While monetary factors suggest that changes brought about by the 24/7 society will generally be self-correcting at the macro-economic level, there will nevertheless be effects for individuals, such as potentially severe impacts on the fuel poor as electricity prices rise. We conclude with a view of future directions. As the 24/7 culture continues to grow, there is scope for designers and for information technology to manage and reduce energy consumption. This includes buildings, their services systems, and the mix of new technologies that will be deployed over the next 20 years or so, including the possibilities for data exchange and control at the interface between energy suppliers and consumers, coupled with greater understanding of the behaviour of the consumers themselves.

  7. Review of the study &apos;&apos;Development of the energy markets - energy reference forecast&apos;&apos; from the perspective of brown coal; Bewertung der Studie &apos;&apos;Entwicklung der Energiemaerkte - Energiereferenzprognose&apos;&apos; aus Sicht der Braunkohle

    Energy Technology Data Exchange (ETDEWEB)

    Dyllong, Yvonne [DEBRIV e.V., Koeln (Germany); Maassen, Uwe [Statistik der Kohlenwirtschaft e.V., Koeln (Germany)

    2014-12-15

    In June 2014 the Federal Ministry for Economic Affairs and Energy (BMWi) published an expertise prepared by the EWI, GWS and Prognos institutes entitled &apos;&apos;Development of the energy markets - energy reference forecast&apos;&apos;. This study presents probable developments in the energy economy up to the year 2030 (reference forecast) on the assumption of a yet more stringent energy and climate protection policy as well as continuing impediments to its implementation. Complementing the forecast is an outlook up to the year 2050 (scenario of trends). But what do the findings of this expertise say about the future utilization of Germany&apos;s greatest domestic energy resource, namely brown coal? This question is addressed in the following article.

  8. Why Germany&apos;s &apos;Messy&apos; energy transition should be a lesson to other nations

    Energy Technology Data Exchange (ETDEWEB)

    Shepherd, John [nuclear 24, Brighton (United Kingdom)

    2015-03-15

    Germany&apos;s so-called &apos;&apos;energy transition&apos;&apos; (&apos;'Energiewende'&apos;) is increasingly drawing the intention of the international community - but it seems for all the wrong reasons. US Senator Lamar Alexander said recently that German energy policy is one of the reasons the US should not abandon nuclear, but actually encourage increased investment in nuclear power plants. Alexander&apos;s remarks were made in an article published by the US Nuclear Energy Institute, in which he outlined his reasons why the US should not follow Germany&apos;s lead. Alexander rightly pointed out that the cost of attempting to replace nuclear power with wind, solar, and accompanying infrastructure is estimated by the German government at some 1.2 trillion US dollars (about 1 trillion Euros). The senator also made the point that Germany &apos;&apos;does not produce enough reliable, baseload energy for an important manufacturing economy&apos;&apos;. He also expressed concern at Germany&apos;s reliance on buying natural gas from Russia. While Germany has been forcing the closure of nuclear power plants others, including the oil-rich United Arab Emirates (UAE), have been investing in new nuclear, Alexander said. Judging from Alexander&apos;s remarks, it seems that Germany&apos;s energy transition experience will, after all, have a long-lasting legacy. That legacy will be a valuable lesson to other major industrialised nations in why they should not follow Germany&apos;s lead in abandoning a sensible energy mix, if they wish to maintain and develop economic and industrial productivity while keeping to international commitments to tackle climate change.

  9. Avaliação Do Tratamento Da Paracoccidioidomicose Com O Ketoconazol

    Directory of Open Access Journals (Sweden)

    Jussara Marcondes

    1984-04-01

    Full Text Available Foram, tratados 12 doentes atendidos na Disciplina de Moléstias Infecciosas e Parasitárias da Faculdade de Medicina de Botucatu com diagnóstico etiológico de paracoccidioidomicose que apresentavam lesões orgânicas múltiplas e evolução prolongada. O tratamento foi realizado por 18 meses, com o ketoconazol, pela via oral, nas doses diárias de 400 mg no primeiro mês e de 200 mg nos meses seguintes. Todos os doentes foram acompanhados durante o tratamento e, em média 4 meses e meio após o mesmo, clínica, radiológica e sorologicamente pelas reações de imunofluorescência indireta, precipitinas e imunodifusão em gel. A competência imunitária foi avaliada em todos os doentes antes do tratamento e repetida em quatro, no final do mesmo. Os resultados mostraram que houve recaída em 5 doentes. A droga foi bem tolerada e a imunodifusão em gel e a hemossedimentação foram as provas que mostraram maior paralelismo com a evolução clínica.

  10. THE LONG-LIVED UV &apos;'PLATEAU'&apos; OF SN 2012aw

    Energy Technology Data Exchange (ETDEWEB)

    Bayless, Amanda J.; Roming, Peter W. A. [Southwest Research Institute, Department of Space Science, 6220 Culebra Road, San Antonio, TX 78238 (United States); Pritchard, Tyler A. [Department of Astronomy and Astrophysics, Penn State University, 525 Davey Lab, University Park, PA 16802 (United States); Kuin, Paul [Mullard Space Science Laboratory, Holmbury St. Mary, Dorking, Surrey RH5 6NT (United Kingdom); Brown, Peter J. [Texas A and M University, Department of Physics and Astronomy, College Station, TX 77843-4242 (United States); Botticella, Maria Teresa; Dall' Ora, Massimo [INAF-Osservatorio Astronomico di Capodimonte, via Moiariello 16, I-80131 Napoli (Italy); Frey, Lucille H.; Even, Wesley; Fryer, Chris L. [Los Alamos National Laboratory, Los Alamos, NM 87545 (United States); Maund, Justyn R.; Fraser, Morgan [Astrophysics Research Center, School of Mathematics and Physics, Queen' s University Belfast, Belfast BT7 1NN (United Kingdom)

    2013-02-10

    Observations with the Swift UV Optical Telescope have unambiguously uncovered for the first time a long-lived, UV &apos;'plateau'&apos; in a Type II-P supernova (SN). Although this flattening in slope is hinted at in a few other SNe, due to its proximity and minimal line-of-sight extinction, SN 2012aw has afforded the first opportunity to clearly observe this UV plateau. The observations of SN 2012aw revealed all Swift UV and u-band light curves initially declined rapidly, but 27 days after the explosion the light curves flattened. Some possible sources of the UV plateau are the same thermal process that causes the optical plateau, heating from radioactive decay, or a combination of both processes.

  11. Tratamento conservador dos hematomas extradurais laminares na infância

    Directory of Open Access Journals (Sweden)

    Orildo Ciquini Júnior

    1992-12-01

    Full Text Available Os autores relatam sua experiência com o tratamento conservador de 15 crianças com hematoma extradural (HED laminar traumático. Todas, por ocasião do diagnóstico, apresentavam-se neurologicamente estáveis e sem sinais de herniação intracraniana. Estes HED foram descobertos em períodos de 30 minutos e 5 dias depois do trauma, a maioria estando localizados na região parietal. OHED foi reabsorvido espontaneamente em todos os casos, num período que variou de 2 a 12 dias. Os critérios para seleção destes pacientes e os cuidados com essa modalidade de tratamento do HED são discutidos.

  12. Experiences from the exercise &apos;'MERLIN'&apos; for the detection of radioactive substances with the participation of special-purpose vehicles; Erfahrungen aus der Uebung &apos;'MERLIN'&apos; zur Detektion radioaktiver Stoffe unter Beteiligung verschiedenen Einsatzfahrzeuge

    Energy Technology Data Exchange (ETDEWEB)

    Griesbach, M. [Hessisches Ministerium des Innern und fuer Sport, Wiesbaden (Germany)

    2009-08-15

    Experiences of an exercise with hazardous goods, in particular with radioactive substances (measurements and taking environmental samples) are described. Several special-purpose vehicles with equipment and specially trained crews were used together with radiation protection experts according to the concept of Hesse. It has been the greatest exercise in Hesse with regard to hazardous goods and in particular with regard to &apos;&apos;incidents with radioactive substances&apos;&apos;. (orig.)

  13. Thirty years ago: &apos;&apos;InterCity 79&apos;&apos; - every hour, every class; Vor 30 Jahren: IC 79 - jede Stunde - jede Klasse

    Energy Technology Data Exchange (ETDEWEB)

    Jaensch, Eberhard

    2009-05-15

    The &apos;&apos;IC 79&apos;&apos; system, which was introduced thirty years ago, has permanently moulded the shape of long-distance passenger services in Germany (with Deutsche Bundesbahn and later Deutsche Bahn). Since then, top-grade passenger trains have been running regularly every hour on several routes. They provide links with short travel times between the country&apos;s most important towns and cities. &apos;&apos;IC 79&apos;&apos; became the backbone of long-distance rail travel in Germany. The ideas underlying it and the way they were implemented are still considered exemplary today. (orig.)

  14. The implementation of the &apos;&apos;Smart Grid&apos;&apos; - preached but not practised; Die Realisierung des &apos;&apos;Smart Grids&apos;&apos;. In aller Munde, aber nicht in der Umsetzung

    Energy Technology Data Exchange (ETDEWEB)

    Augenstein, Friedrich [Duale Hochschule Baden-Wuerttemberg, Stuttgart (Germany). Bereich BWL-Dienstleistungsmanagement; Einhellig, Ludwig; Kohl, Ingmar [Deloitte, Muenchen (Germany)

    2011-07-15

    The development of smart power grids is still in its infancy in Germany, in spite of extensive pilot programmes, competition from foreign power suppliers as well as unanimous opinion among experts that there is no way around them. Although a legal obligations has existed since the beginning of this year to offer &apos;'variable-load'&apos; tariffs, and despite their being desired by the political realm and having been laid down in the Energy Concept of the Federal Government, lack of consumer demand has so far inhibited the development of intelligent grids. But is it really because of the consumer, or is it more due to other parameters that Germany is threatening to lose the race in smart grid technology.

  15. Environmental and safety aspects. The best of &apos;powder handling and processing&apos; 1989 - 1997. &apos;Bulk solids handling&apos; 1992 - 1997 (H/2000)

    Energy Technology Data Exchange (ETDEWEB)

    Woehlbier, R.H. (ed.)

    2000-07-01

    The book contains articles published either during 1992-1997 in &apos;&apos;bulk solids handling&apos;&apos; or during 1989-1997 in &apos;&apos;powder handling and processing&apos;&apos;. Main topics are aspects of safety and environmental protection in bulk solids handling: dusts, hazardous powders, prevention and mitigation of dust explosions, powdered coal handling, dedusting, filters, electrostatic precipitation, materials recovery, occupational safety.(uke)

  16. A utilização de mini-estações de tratamento de esgoto em residências

    Directory of Open Access Journals (Sweden)

    Nícolas Fernandes Martins

    2013-09-01

    Full Text Available O presente trabalho tratará do desenvolvimento de um protótipo de estação detratamento de esgoto (ETE, sendo um protótipo onde foram analisados dadosquímicos e levantamento da microfauna do lodo ativado.  Foram analisados antes eapós o tratamento do protótipo dados referentes à Demanda Bioquímica de Oxigênio(DBO, Nitrogênio Amoniacal, fosfato, óleos e graxas, ph e espectrofotometria. É oprimeiro trabalho que utiliza medidas de espectrofotometria em analises de águastratadas. Todos os resultados comprovam que a estação de tratamento pode ser eficazem residências que não possuem tratamento de esgoto. Foram realizadas plantas parainstalação de uma estação de tratamento em residências.

  17. Scientists from all over the world attend the &apos;&apos;Frederic Joliot/Otto Hahn Summer School 2009&apos;&apos; at the Karlsruhe Institute of Technology (KIT); Wissenschaftler aus aller Welt bei der &apos;&apos;Frederic Joliot/Otto Hahn Summer School 2009&apos;&apos; am Karlsruhe Institute of Technologie (KIT)

    Energy Technology Data Exchange (ETDEWEB)

    Sanchez Espinoza, Victor Hugo; Fischer, Ulrich [Karlsruhe Inst. of Tech. (KIT), Campus Nord/Inst. for Neutron Physics and Reactor Tech. (INR), Eggenstein-Leopoldshafen (Germany)

    2009-11-15

    The &apos;&apos;Frederic Joliot/Otto Hahn Summer School&apos;&apos; is organized each year alternately by the Karlsruhe Institute of Technology and the Commissariat a l&apos;Energie Atomique (CEA), Cadarache. This year&apos;s Summer School, the 15th since its foundation, was run at the Advanced Training Center (FTU) of KIT Campus Nord on August 26 to September 4. The key topic this year was &apos;&apos;The Challenges in Implementing Fast Reactor Technology.&apos;&apos; These are the items discussed: Principles and challenges of future fast reactor designs, Fuels, fuel cycle, and recycling of minor actinides, Innovative cladding tube and structural materials, Special aspects of coolants and the challenges they pose, Fast reactor safety. Experts from 8 leading international research establishments and universities presented and discussed with the 58 participants from 16 countries the current state of the art and the latest development trends in the topics listed above. (orig.)

  18. Escala clínica para prever a adesão ao tratamento: transtorno bipolar do humor

    OpenAIRE

    Marchi, Renato

    2008-01-01

    O Transtorno Bipolar do Humor (TBH) está associado a altas taxas de desajustes psicossociais e familiares, mortalidade e prejuízos econômicos. O tratamento visa o controle de episódios agudos e prevenção de novos episódios. As taxas de não - adesão ao tratamento são altas em TBH. Este trabalho teve por objetivo elaborar e validar uma escala de avaliação clinica , capaz de indicar a probabilidade de adesão ao tratamento medico clinico dos pacientes bipolares de ambos os gêneros. O procedimento...

  19. A importância da família no tratamento do uso abusivo de drogas: uma revisão da literatura

    Directory of Open Access Journals (Sweden)

    Schenker Miriam

    2004-01-01

    Full Text Available Este artigo apresenta uma revisão da literatura sobre as duas fases do tratamento do adicto e de sua família: o engajamento e o tratamento propriamente ditos. Ressalta, através de diversos estudos, a necessidade do adicto ser atendido juntamente com a sua família para um resultado satisfatório do tratamento. Aponta para questões socioculturais importantes que interferem no tratamento realizado em Instituições. Enfatiza que o tratamento do adicto e de sua família contribui para o entendimento e as bases de uma ação efetiva de prevenção.

  20. Alteração da cor da madeira de teca por tratamento térmico

    Directory of Open Access Journals (Sweden)

    Juliana de Oliveira Lopes

    Full Text Available O objetivo deste estudo foi determinar o efeito do tratamento térmico na alteração da cor da madeira de teca (Tectona grandis L. f., proveniente de plantios de diferentes espaçamentos. Amostras de madeira de cerne e de alburno foram tratadas a 180 e 200ºC durante 2h30min. As análises colorimétricas foram realizadas com o auxílio do espectrofotômetro CM 2600d no sistema CIE L*a*b*. Após o tratamento, a madeira teve perda de luminosidade, tornado-se mais escura, o que se mostrou mais acentuado para o tratamento a 200ºC. As madeiras de cerne e alburno apresentaram comportamentos diferentes para as coordenadas a* e b*, dependendo do espaçamento, antes e após o tratamento. Ocorreu uma maior formação de pigmento vermelho e perda de pigmento amarelo nas madeiras de cerne e alburno tratadas a 200ºC.

  1. &apos;&apos;Camouflage line&apos;&apos; for 380 kV; Erfahrungen mit einer 380-kV-&apos;'Tarnleitung'&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Egger, H. [FAS Berndorf GmbH and Co. KG, Berndorf (Austria); Lugschitz, H. [Verbund-Austrian Power Grid GmbH, Wien (Austria)

    2000-10-16

    Overhead transmission lines are under increased public discussion. One method to minimize their influence on the environment and therefore to increase their acceptance is to camouflage lines by coating their components. Towers, conductors and fittings of a line which was erected recently in the Austrian Alps are coated in dark green colour to make the structure less visible against the background. For further reduction of visibility the line is constructed as compact line. The smaller tower size was achieved by use of short insulator strings and by oversized conductors with special advantageous mechanical properties. This paper explains the consideration which led to the configuration as compact line and for the decision to coate the complete line. It also presents long term experience with in-factory-coating of towers. Factory-coated supports were introduced 1982 in the company&apos;s network, first with the main goal to ease maintenance and second to reduce impacts on the environment. The first complete &apos;camouflage line&apos; (coloured supports and coloured conductors) in the Austrian grid was set into operation end of the year 1995. (orig.) [German] Freileitungen stehen unter zunehmender oeffentlicher Diskussion. Eine der Methoden, ihren Einfluss auf die Umwelt zu reduzieren und damit ihre Akzeptanz zu erhoehen, ist, die Tarnung von Leitungen durch Faerbung ihrer Komponenten. Maste, Leiter, Erdseile und Armaturen einer in den Oesterreichischen Alpen errichtenden Leitungen wurden in dunkelgruener Farbe beschichtet, um die Anlage gegenueber dem Hintergrund geringer sichtbar zu machen. Zur weiteren Reduktion der Sichtbarkeit ist die Leitung als &apos;Kompaktleitung&apos; ausgefuehrt. Die geringeren Mastabmessungen wurden durch die Verwendung von kuerzeren Isolatorenketten und Leiterseilen mit besonders vorteilhaften mechanischen Eigenschaften erreicht. Die Verfasser erklaeren die Ueberlegungen, die zu der Ausfuehrung als Kompaktleitung und zur Beschichtung der

  2. Electrolyzed-water generator &apos;SaniBoy&apos;; Eisei jokinsuik kyokyu sochi &apos;SaniBoy&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Inoue, M.; Kakiuchi, H.; Muto, K. [Fuji Electric Co. Ltd., Tokyo (Japan)

    2000-03-10

    In the food industry, injuries due to food poisoning have been increasing. Especially the mass outbreak of food poisoning by Escherichia coli such as O-157 in 1996 gave warning on the importance of food sanitation management. Public efforts such as the Hazard Analysis and Critical Control Point (HACCP) system have been made to prevent food poisoning. Recently, disinfection made by electrolyzing water with some salt added has attracted attention. Fuji Electric has developed the generator &apos;SaniBoy&apos; that produces weak alkaline electrolyzed water without wasting water. The environment-friendly &apos;SaniBoy&apos; will contribute to sanitation in various fields. (author)

  3. Short circuit - How our power supply became more expensive and got worse. A critical balance after eight years &apos;'deregulation'&apos; of the German Energy Economy; Kurzschluss - Wie unsere Stromversorgung teurer und schlechter wurde. Eine kritische Bilanz nach acht Jahren &apos;'Liberalisierung'&apos; der deutschen Energiewirtschaft

    Energy Technology Data Exchange (ETDEWEB)

    Leuschner, U.

    2007-07-01

    Since 16 years the author, a journalist, pursues the economical and political development of the German power economy. Many facts of this book prove: the impacting consequences as the clear scarcity of 1998 introduced deregulation, which has permitted 8 years long the discrimination of competitors and enabled in this way an exampleless concentration of market might (pt. 1); how supply reliability became worse and power and gas got more and more expensive (pt. 2); the complete insufficient practice of cartel agreements which is exchanged by administrative grid charges respectively &apos;&apos;incentive regulation&apos;&apos; (pt. 3); the relation between management and policy which has become still more distantless than in the epoche of membership books (pt. 4); the development of the German power economy from the beginning in the 19th century to the deregulation incl. the reorganization on the area of the former German Democratic republic. (GL) [German] Im ersten Teil des Buches (&apos;&apos;Stromwirtschaft im Umbruch&apos;&apos;) befasst sich Leuschner nun noch eingehender mit den politischen Hintergruenden der verfehlten Deregulierung. Er stellt fest, dass es die letzte Regierung unter Helmut Kohl war, die von Anfang an die Weichen falsch gestellt hat. Die Hauptverantwortung fuer die Nichtkorrektur des Fehlers und den fortgesetzten &apos;&apos;Schmusekurs mit den Konzernen&apos;&apos; sieht er aber bei den beiden folgenden rot-gruenen Bundesregierungen. Er verdeutlicht ferner, dass die erhoehten Belastungen durch Stromsteuer, EEG und KWK-Gesetz keine hinreichende Begruendung fuer den Strompreisanstieg liefern. Wo nicht minder wichtige Faktoren fuer den Preisanstieg liegen, veranschaulicht er im Kapitel ueber die &apos;&apos;Preisveredelung an der EEX&apos;&apos;. Im zweiten Teil, der die technischen Hintergruende und Risiken der Deregulierung behandelt, findet man jetzt auch ausfuehrlich die europaweite Netzstoerung beschrieben, die EON am 4. November 2006

  4. Resultado do tratamento cirúrgico das neoplasias do seio piriforme

    Directory of Open Access Journals (Sweden)

    Costa Claudiney C.

    2003-01-01

    Full Text Available Os tumores da laringe e hipofaringe apresentam alta incidência no Brasil, sendo o sexto sítio mais comum entre os tumores malignos no sexo masculino. O diagnóstico inicial geralmente é realizado com lesões em estadio clínicos avançados diminuindo o sucesso do tratamento instituído. OBJETIVOS: Avaliar a evolução de 60 pacientes com carcinoma epidermóide de seio piriforme, considerando tratamento instituído, complicações e sobrevida estimada em 5 anos. FORMA DE ESTUDO: Estudo retrospectivo. MÉTODO: Os testes estatístico utilizados foram o método de Kaplan-Meier e o teste exato de Fisher. RESULTADOS: Dos 60 pacientes, 43 foram submetidos a tratamento cirúrgico seguido de radioterapia. Atualmente 27,9% estão vivos sem doença, 11,6% vivos com doença, 9,4% mortos sem doença, 34,8% mortos com doença e perda de seguimento de 16,3%. A complicação pós-operatória mais freqüente foi a fístula cutânea. A recidiva local ocorreu em 5 pacientes, regional em 6, loco-regional em 3 e metástase à distância em 6. Não houve correlação entre margem cirúrgica comprometida e sobrevida em 20 pacientes com recidiva tumoral (Teste de Fisher. Aplicando a curva de sobrevida atuarial pelo método Kaplan-Meier, obtivemos média de sobrevida em 5 anos de 23,2 meses. CONCLUSÃO: A principal complicação pós-operatória foi a fístula cutânea, sendo tratada clinicamente. A margem cirúrgica comprometida não alterou o prognóstico, apesar de ser sempre um dos princípios da cirurgia oncológica. A principal falha no tratamento foi a recidiva locorregional. A curva de sobrevida atuarial (Kaplan-Meier em cinco anos apresentou média de 23,2 meses.

  5. The United States and international climate cooperation: International &apos;pull&apos; versus domestic &apos;push&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Bang, Guri [Center for International Climate and Environmental Research, Oslo (Norway); Froyn, Camilla Bretteville [Center for International Climate and Environmental Research, Oslo (Norway); Hovi, Jon [Center for International Climate and Environmental Research, Oslo (Norway) and Department of Political Science, University of Oslo, P.O. Box 1097, 0317 Oslo (Norway)]. E-mail: jon.hovi@stv.uio.no; Menz, Fredric C. [Center for International Climate and Environmental Research, Oslo (Norway); School of Business, Clarkson University, Potsdam, NY 13699 (United States)

    2007-02-15

    The US government is being pressured by both international and domestic influences to re-engage in international climate control. This paper considers whether the international &apos;pull&apos; and the domestic &apos;push&apos; will be strong enough to accomplish this. First, we discuss whether changes in the architecture of the current climate regime might induce the United States to re-engage at the international level. We argue that the United States is unlikely to rejoin any global climate regime that is based on the Kyoto architecture, even if Kyoto were to be &apos;reformed&apos;. Second, we discuss whether domestic political developments might eventually cause the United States to re-engage. We conclude that US re-engagement is likely to require the emergence of a new climate regime that basically extends US regulation to other countries. However, the forging of a unified US climate policy is still in the making. Furthermore, a new regime can gain widespread participation only if the Kyoto countries accept the idea of replacing Kyoto with some alternative architecture, which seems unlikely in the near future.

  6. Accidents, &apos;black swans&apos; and risks

    Energy Technology Data Exchange (ETDEWEB)

    Luxat, J.C. [McMaster Univ., Dept. of Engineering Physics, Hamilton, Ontario (Canada)

    2013-06-15

    Major accidents and natural disasters with severe consequences have occurred in all sectors of industrial activity with relatively high frequency. The severe consequences of concern involve either significant loss of life or major economic loss, or both loss of life and economic loss. Such events have the last two years been referred to as &apos;black swan&apos; events following publication of Taleb&apos;s bestselling book. These events demonstrate limits to PRA application that arise from the underlying high uncertainty associated with the estimation of frequency of occurrence of such events. An approach is proposed in this paper that, consistent with the concept of defense in depth employed by the nuclear industry, augments probabilistic risk assessment with a methodology based upon &apos;threat - risk assessment&apos;. This approach shifts these very low frequency high consequence &apos;black swan&apos; events out of the probabilistic risk assessment domain into a deterministic emergency response assessment domain. (author)

  7. Bookshelf (&apos;&apos;Neutrons, Nuclei and Matter&apos;&apos;, by J. Byrne)

    International Nuclear Information System (INIS)

    Hansen, P.G.

    1994-01-01

    Time was when a neophyte wanting to do experiments with neutrons would be told first to read D.J. Hughes&apos; classic &apos;&apos;Pile Neutron Research&apos;&apos; (1952). The book by J. Byrne is in many respects a modern equivalent, although if you were to send your student away with it, you will risk not seeing him or her again for a considerable time. What is immediately striking is that the book, rich in information and quite long, is cross-disciplinary and touches essentially all the main areas of modern physics. It covers parts of particle physics, such as the internal structure of the neutron, time-reversal violation as revealed by the (still hypothetical) electric dipole moment of the neutron, and the coupling constants for the weak interaction. From the field of basic quantum physics there are chapters on neutron optics, wave phenomena with neutrons and on the applications of these in solid-state physics. Other chapters again delve deeply into nuclear structure, nuclear reaction theory, as well as their applications: nuclear reactors and nuclear energy. At a time with specialization rampant and many physicists tending to believe that venturing outside their own cloisters is uninteresting and even dangerous, it is a pleasure to come across a book that is basically just about physics. J. Byrne of Sussex has for long been active in neutron research at the British-French-German Institut Laue-Langevin (ILL) research reactor in Grenoble, where he has worked on subjects such as weak interactions and fundamental symmetries. He has clearly intended &apos;&apos;Neutrons, Nuclei and Matter&apos;&apos; as a vade-mecum that will allow the practitioner to find the necessary information and formulas. But I believe that many others not directly engaged in neutron research will gain new insight from its many examples. To take just one case, I had not been aware of the simple physical principles that permit cold neutrons to be stored in a bottle. (The main point is that a

  8. On the universality of the &apos;'smile'&apos;-gap in the density of states of a chaotic Josephson junction

    Energy Technology Data Exchange (ETDEWEB)

    Reutlinger, Johannes; Belzig, Wolfgang [University of Konstanz, Department of Physics (Germany); Nazarov, Yuli [Kavli Institute of Nanoscience Delft, Delft University of Technology, Delft (Netherlands); Glazman, Leonid [Department of Physics, Yale University, New Haven, CT (United States)

    2015-07-01

    The superconducting proximity effect strongly modifies the local density of states in chaotic Josephson junctions. Recently we found that besides the well-known minigap a secondary gap appears just below the superconducting gap edge Δ in the limit of a large Thouless energy E{sub Th} >or similar Δ. To check the universality of this novel gap phenomenon we study the effect of nonideal contacts and show that the &apos;'smile'&apos;-gap crucially depends on the transmission eigenvalue distribution. In a next step we use the random matrix method to investigate the &apos;'smile'&apos;-gap. This allows us to approach the statistics of Andreev levels, going beyond the quasiclassical Greens function method. It turns out that the hard gap edge softens similar to what is already known from the minigap.

  9. &apos;&apos;Confession statement against the nuclear nation&apos;&apos;. The protestant church in Germany and the conflicts concerning nuclear energy 1970 - 1990; &apos;&apos;Bekennen gegen den Atomstaat&apos;&apos;. Die evangelischen Kirchen in der Bundesrepublik Deutschland und die Konflikte um die Atomenergie 1970-1990

    Energy Technology Data Exchange (ETDEWEB)

    Schuering, Michael [Florida Univ., Gainesville, FL (United States)

    2015-07-01

    The book on &apos;&apos;Confession statement against the nuclear nation&apos;&apos; discusses the conflicts of the protestant church in Germany concerning nuclear energy in 1970 - 1990. The introduction covers the state of research and the historical sources. The following chapters discuss the issues philosophic-ideological fundamentals: atomic energy and theology, the political church, the new protest culture and comparative perspectives: the catholic perspective, Three Mile Island&apos;s shadow.

  10. EAGLE: &apos;EAGLE&apos;Is an&apos; Algorithmic Graph Library for Exploration

    Energy Technology Data Exchange (ETDEWEB)

    2015-01-16

    The Resource Description Framework (RDF) and SPARQL Protocol and RDF Query Language (SPARQL) were introduced about a decade ago to enable flexible schema-free data interchange on the Semantic Web. Today data scientists use the framework as a scalable graph representation for integrating, querying, exploring and analyzing data sets hosted at different sources. With increasing adoption, the need for graph mining capabilities for the Semantic Web has emerged. Today there is no tools to conduct "graph mining" on RDF standard data sets. We address that need through implementation of popular iterative Graph Mining algorithms (Triangle count, Connected component analysis, degree distribution, diversity degree, PageRank, etc.). We implement these algorithms as SPARQL queries, wrapped within Python scripts and call our software tool as EAGLE. In RDF style, EAGLE stands for "EAGLE &apos;Is an&apos; algorithmic graph library for exploration. EAGLE is like &apos;MATLAB&apos; for &apos;Linked Data.&apos;

  11. The development and treatment of impulsivity = O desenvolvimento e tratamento da impulsividade

    Directory of Open Access Journals (Sweden)

    Amorim Neto, Roque do Carmo

    2011-01-01

    Full Text Available Impulsividade é um fator presente em várias desordens psicológicas, incluindo ADHD, drogadição, comportamentos agressivos e automutiladores, e obesidade infantil. Impulsividade também é um fator de risco para o abandono de tratamento. Este artigo tem por objetivo apresentar as raízes da impulsividade do ponto de vista biológico, sociológico e do desenvolvimento humano, bem como as formas de tratamento mais comuns para pessoas com extrema impulsividade. Aqui também se inclui pesquisas das áreas de desenvolvimento neuronal e regulação emocional

  12. Transtorno bipolar : adesão ao tratamento e psicoeducação

    OpenAIRE

    Samir Vidal Mussi

    2012-01-01

    A psicoeducação é uma das estratégias que deve ser inserida no tratamento de pacientes com diagnóstico de transtorno bipolar e tem demonstrado eficácia para fomentar respostas relacionadas à adesão à medicação. O objetivo deste estudo foi avaliar a efetividade de um programa de psicoeducação aplicado a 9 pacientes com diagnóstico de transtorno bipolar, em tratamento em um hospital público. Para avaliação foram aplicadas as escalas de depressão (Hamilton), de mania (Young) e de Qualidade de Vi...

  13. ApoE4-specific Misfolded Intermediate Identified by Molecular Dynamics Simulations.

    Directory of Open Access Journals (Sweden)

    Benfeard Williams

    2015-10-01

    Full Text Available The increased risk of developing Alzheimer's disease (AD is associated with the APOE gene, which encodes for three variants of Apolipoprotein E, namely E2, E3, E4, differing only by two amino acids at positions 112 and 158. ApoE4 is known to be the strongest risk factor for AD onset, while ApoE3 and ApoE2 are considered to be the AD-neutral and AD-protective isoforms, respectively. It has been hypothesized that the ApoE isoforms may contribute to the development of AD by modifying the homeostasis of ApoE physiological partners and AD-related proteins in an isoform-specific fashion. Here we find that, despite the high sequence similarity among the three ApoE variants, only ApoE4 exhibits a misfolded intermediate state characterized by isoform-specific domain-domain interactions in molecular dynamics simulations. The existence of an ApoE4-specific intermediate state can contribute to the onset of AD by altering multiple cellular pathways involved in ApoE-dependent lipid transport efficiency or in AD-related protein aggregation and clearance. We present what we believe to be the first structural model of an ApoE4 misfolded intermediate state, which may serve to elucidate the molecular mechanism underlying the role of ApoE4 in AD pathogenesis. The knowledge of the structure for the ApoE4 folding intermediate provides a new platform for the rational design of alternative therapeutic strategies to fight AD.

  14. HEMOFILIAS: FISIOPATOLOGIA, DIAGNÓSTICO E TRATAMENTO

    Directory of Open Access Journals (Sweden)

    Roberta Truzzi COLOMBO, Gerson ZANUSSO JÚNIOR

    2013-12-01

    Full Text Available A hemofilia é um grave distúrbio hereditário da coagulação sanguínea, causada pela deficiência da atividade coagulante do fator VIII (hemofilia A ou IX (hemofilia B. A doença é decorrente de alterações nos genes codificantes destes fatores localizados no braço longo do cromossomo sexual X. Assim sua ocorrência no sexo masculino é quase que exclusiva, devido o homem apresentar somente um cromossomo X. A gravidade da doença pode variar em severa, moderadamente severa e leve, após dosagem dos fatores VIII e IX da coagulação. Uma das complicações mais temíveis dos pacientes com esta doença refere-se ao desenvolvimento de inibidores, que são anticorpos direcionados contra os fatores infundidos. O diagnóstico da doença é realizado através de exames laboratoriais, principalmente pelo coagulograma completo e dosagem de fatores específicos, baseando-se nas manifestações clínicas apresentadas pelo paciente. A hemofilia não tem cura e a base do seu tratamento é a infusão do concentrado do fator deficiente. No entanto, pacientes podem desenvolver inibidores específicos para os fatores infundidos e, nestes casos as alternativas de tratamento são o uso da biotecnologia para novos medicamentos e o uso da terapia gênica

  15. Technology centre &apos;&apos;aspern IQ&apos;&apos;. Office buildings in the plus-energy building as a benchmark for future projects; Technologiezentrum &apos;&apos;aspern IQ&apos;&apos;. Buerohaus im Plus-Energie-Standard als Benchmark fuer kuenftige Projekte

    Energy Technology Data Exchange (ETDEWEB)

    Achammer, Hannes [ATP Wien (Austria); IWP Liebhartstal II, Wien (Austria); Technologiezentrum aspern IQ, Wien (Austria)

    2012-11-01

    With 240 hectares per 20,000 residents and working people the future seaside town Aspern is one of the largest urban development projects in Europe and the largest in Vienna (Austria). At the end of August 2012, the component 1 of the technology centre &apos;&apos;aspern IQ&apos;&apos; of the Vienna Business Agency has been completed at the first construction site. This first building construction was designed in the plus-energy standard. As a flagship project it exemplary shall be adapted to the local resource supply, provide the highest possible user experience and meet the requirements of sustainability.

  16. Metrology for the radiological early warning system in Europe. The &apos;'MetroERM'&apos; project; Metrologie fuer die radiologischen Fruehwarnsysteme in Europa. Das &apos;'MetroERM'&apos;-Projekt

    Energy Technology Data Exchange (ETDEWEB)

    Neumaier, Stefan; Dombrowski, Harald [Physikalisch-Technische Bundesanstalt, Braunschweig (Germany)

    2017-10-01

    In the European radiological early warning system about 5500 stationary sensors are actually implemented that measure continuously the local dose rate. Alongside several hundred air dust collecting systems attribute to the measurement of airborne radioactivity. The local dose rates are transmitted hourly to a central data base that is operated on behalf of the EU commission. In significantly larger time intervals the measured data of the airborne radioactivity are transmitted. In case of a cross-border radiological accident these data are the basis for recommendations given by the EU commission to the member states for national counter measures. The focus of the project &apos;&apos;Metrology for radiological early warning networks in Europe&apos;&apos; is an improvement of the metrological quality and harmonization these data and the development of improved measuring systems and evaluation methods.

  17. Developmental coxa vara associated with spondylometaphyseal dysplasia (DCV/SMD): &apos;&apos;SMD-Corner Fracture Type&apos;&apos; (DCV/SMD-CF) demonstrated in most reported cases

    Energy Technology Data Exchange (ETDEWEB)

    Currarino, G. [Texas Univ., Dallas, TX (United States). Dept. of Radiology; Department of Radiology, Texas Scottish Rite Hospital for Children, 2222 Welborn Street, Dallas, TX 75219 (United States); Birch, J.G.; Herring, J.A. [Department of Orthopedic Surgery, Texas Scottish Rite Hospital for Children, Dallas, TX (United States)

    2000-01-01

    Background. This paper reports three children with short stature: developmental coxa vara unilateral in the first case and bilateral in the other two; somewhat squared and &apos;'ovoid'&apos; vertebral bodies in the first patient, and normal to slightly tall vertebral bodies in the third; metaphyseal changes in some long tubular bones including bone fragments similar to the corner fractures seen in child abuse in all three patients. Materials and methods. The first and second patients were sisters; their mother, also quite short, had surgical procedures in early life for bilateral &apos;&apos;coxa vara&apos;&apos;; their brother, also of short stature, had bilateral coxa valga with otherwise normal femoral heads and necks, and mild metaphyseal changes associated with two minute &apos;&apos;corner fractures&apos;&apos; in the proximal metaphysis of the left tibia. Results. A review of reported cases of developmental coxa vara associated with spondylometaphyseal dysplasia revealed that simulated corner fractures were present in most instances. (orig.)

  18. Tratamento cirúrgico da laringomalácia grave: estudo retrospectivo de 11 casos

    Directory of Open Access Journals (Sweden)

    José Antonio Pinto

    2013-10-01

    Full Text Available A laringomalácia é a anomalia congênita da laringe mais frequente, sendo responsável por cerca de 60% a 75% dos casos de estridor congênito. Apesar de seu curso benigno e autolimitado, 10% dos casos necessitam de intervenção. Atualmente, as supraglotoplastias são consideradas o tratamento padrão da laringomalácia grave. OBJETIVO: Descrever a experiência adquirida pelos autores no tratamento cirúrgico dos pacientes com laringomalácia grave. Metodologia: Estudo retrospectivo. MÉTODO: Os prontuários de 11 casos consecutivos de laringomalácia grave, submetidos ao tratamento cirúrgico entre 2003 e 2012, foram analisados quanto à idade, gênero, sintomas, doenças associadas, técnica cirúrgica adotada, tempo de extubação, complicações cirúrgicas, tempo de internação e evolução clínica. RESULTADOS: Dos 11 casos de laringomalácia grave, seis pacientes (54,5% foram operados com o uso do laser de CO2 e em cinco pacientes (45,5% foram realizadas a técnica a frio. Apenas um paciente (9,1% necessitou reabordagem cirúrgica. Não foram observados casos de complicações cirúrgicas. Todos os pacientes apresentaram melhora clínica importante. CONCLUSÃO: A supraglotoplastia mostrou-se um procedimento eficaz e seguro no tratamento da laringomalácia grave.

  19. Active pollution reduction in the &apos;off-road&apos; sector. Proceedings; Aktive Schadstoffminderung im &apos;Off-road&apos; Bereich. Tagungsband

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2001-07-01

    The state of the art and trends in off-gas purification and filters were gone into. The focus was on technical aspects, performance information and cost of diesel engines with high-efficiency exhaust purification systems as well as on sulfur-free fuels. [German] Mit der Tagung &apos;Aktive Schadstoffminderung im &apos;'Off-road'&apos; Bereich&apos; bieten wir eine besondere Gelegenheit zur Information und Auseinandersetzung mit dem derzeitigen Stand und den Entwicklungsperspektiven der Abgasreinigung und Filtertechnik bei Neubeschaffungen und in der Nachruestung. Gerade in staedtischen Ballungsgebieten, aber auch in geschlossenen Raeumen und Produktionshallen sind die Reduzierung der lokalen Emissionen und Vermeidung von Geruchsbelaestigungen unabdingbar. Im Mittelpunkt stehen Technik, Betriebserfahrungen und Kosten von Dieselmotoren mit hocheffizienter Abgasreinigung sowie schwefelfreie Kraftstoffe. (orig.)

  20. Proliferation Resistance and Safeguards by Design: The Safeguardability Assessment Tool Provided by the INPRO Collaborative Project &apos;'INPRO'&apos; (Proliferation Resistance and Safeguardability Assessment)

    International Nuclear Information System (INIS)

    Haas, E.; Chang, H.-L.; Phillips, J.R.; Listner, C.

    2015-01-01

    Since the INPRO Collaborative Project on Proliferation Resistance and Safeguardability Assessment Tools (PROSA) was launched in 2011, Member State experts have worked with the INPRO Section and the IAEA Department of Safeguards to develop a revised methodology for self-assessment of sustainability in the area of proliferation resistance of a nuclear energy system (NES). With the common understanding that there is &apos;&apos;no proliferation resistance without safeguards&apos;&apos; the revised approach emphasizes the evaluation of a new &apos;User Requirement&apos; for &apos;'safeguardability'&apos;, that combines metrics of effective and efficient implementation of IAEA Safeguards including &apos;'Safeguards-by-Design'&apos; principles. The assessment with safeguardability as the key issue has been devised as a linear process evaluating the NES against a &apos;&apos;Basic Principle&apos;&apos; in the area of proliferation resistance, answering fundamental questions related to safeguards: 1) Do a State&apos;s legal commitments, policies and practices provide credible assurance of the exclusively peaceful use of the NES, including a legal basis for verification activities by the IAEA? 2) Does design and operation of the NES facilitate the effective and efficient implementation of IAEA safeguards? To answer those questions, a questionnaire approach has been developed that clearly identifies gaps and weaknesses. Gaps include prospects for improvements and needs for research and development. In this context, the PROSA approach assesses the safeguardability of a NES using a layered &apos;&apos;Evaluation Questionnaire&apos;&apos; that defines Evaluation Parameters (EP), EP-related questions, Illustrative Tests and Screening Questions to present and structure the evidence of findings. An integral part of the assessment process is Safeguards-by-Design, the identification of potential diversion, misuse and concealment strategies (coarse diversion path

  1. The &apos;&apos;smart consumer&apos;&apos;. Consequences and future challenges from the modified customer role for the established energy supplier; Der &apos;&apos;smarte Verbraucher&apos;&apos;. Konsequenzen und kuenftige Herausforderungen aus der veraenderten Kundenrolle fuer die etablierten Energieversorger

    Energy Technology Data Exchange (ETDEWEB)

    Hense, Andreas [Capgemini Consulting, Koeln (Germany)

    2011-07-01

    Growing decentral generation, digitalization of the whole utilities sector and smart technologies are changing the role fo the &apos;'utilities'&apos; customers. From pure end consumers they will more and more shift to energy-conscious, demanding market players acting as well as producers of energy. This breaks the traditional value chain. In order to participate on the business chances of this development utilities have to build up new, innovative business models around the smart customer. Sustainable success of these approaches depends on some key requirements. (orig.)

  2. IMA status seminar &apos;biotic damaging factors/epidemiology&apos;. Summaries. IMA-Statusseminar &apos;Biotische Schadfaktoren/Epidemiologie&apos;. Kurzberichte

    Energy Technology Data Exchange (ETDEWEB)

    Stuettgen, E. (ed.)

    1986-07-01

    This workshop is concerned primarily with the effects of biotic factors on forest decline. The possible involvement of viruses, mycoplasma-like organisms (MLO), rickettsia-like bacteria (RLB), fungi, insects and nematodes in diseases and pests of forest trees has to be investigated. Beside abiotic factors these agents are the cause of different die-back symptoms and damage of trees, but it is not yet known to what extent they contribute to the symptoms man associate with the forest decline &apos;'Waldsterben'&apos;.

  3. Tratamento cirúrgico da siringomielia pela Técnica de Gardner

    Directory of Open Access Journals (Sweden)

    Gilberto M. Almeida

    1973-12-01

    Full Text Available O tratamento cirúrgico da siringomielia é, em geral, considerado decepcionante. Vários tipos de drenagem da cavidade siringomiélica não têm fornecido resultados satisfatórios. Gardner, em magnífica série de trabalhos, mostrou que a siringomielia e as várias malformações associadas à hidrocefalia têm fisiopatogenia única. Baseado em sua teoria, Gardner propôs, em 1958, o bloqueio da comunicação entre o IV ventrículo e o canal central da medula, para o tratamento da siringomielia. Esta técnica não tem sido realizada com muita freqüência. Empregamos o método proposto por Gardner em 4 pacientes, os quais melhoraram após a intervenção cirúrgica.

  4. Os objetos e o tratamento da criança autista

    Directory of Open Access Journals (Sweden)

    Ariana Lucero

    2015-12-01

    Full Text Available Resumo O objetivo deste artigo é refletir sobre o uso dos objetos na direção de tratamento psicanalítico da criança autista. Primeiramente, teceremos algumas considerações a respeito da importância do objeto na constituição subjetiva, a partir da oposição freudiana entre os princípios de prazer e de realidade. A seguir, retomaremos as considerações de Frances Tustin sobre o objeto autístico e o caso Joey, de Bruno Bettelheim, para exemplificarmos como autores clássicos da psicanálise teorizaram sobre o objeto no tratamento. Por fim, discutiremos com autores contemporâneos a importância de uma retomada da noção de objeto no âmbito da teoria e da prática psicanalíticas.

  5. Probing the existence of the kaonic nuclear cluster &apos;&apos;ppK{sup -}&apos;&apos; with help of a PWA

    Energy Technology Data Exchange (ETDEWEB)

    Epple, Eliane [Physik Dept. E12, Technische Universitaet Muenchen, Garching (Germany); Excellence Cluster ' ' Universe' ' , TEM, Garching (Germany); Collaboration: HADES-Collaboration

    2015-07-01

    The &apos;&apos;ppK{sup -}&apos;&apos; is a well established state in theory and is a candidate for a new kind of hadronic matter formed by antikaons and nucleons. The HADES spectrometer at GSI has probed the existence of such a state by measuring its possible decay products p and Λ. These decay products have been studied specifically in the reaction p+p → p+K{sup +}+Λ at a beam kinetic energy of 3.5 GeV. A partial wave analysis, performed on this final state, helped in describing the event distributions, which is a necessary condition to search for an additional small signal in the statistic. We have found no indication for the production of a kaonic nuclear bound state in our data and have, thus, set an upper limit for its production cross section. Furthermore, did we repeat the analysis of the DISTO collaboration in which a signal like distribution appeared in so-called deviation spectra. We can show that this method is error-prone in terms of the applied selection cuts and is, thus, not reliable in order to make statements about the &apos;&apos;ppK{sup -}&apos;&apos;.

  6. Porosity. &apos;&apos;The good, the bad and ugly&apos;&apos; of Radiographic Testing

    International Nuclear Information System (INIS)

    Vaughan, Hugo

    2016-01-01

    &apos;&apos;Radiographic Testing is a NDT method to detect inherent volumetric discontinuities in materials such as castings and welds&apos;&apos; A common type of discontinuity found and most often misinterpreted and evaluated is rounded indications, whether isolated, aligned or clustered. This paper addresses the acceptance criteria of rounded indications based on various codes and standards and intends to lay at rest the confusion related to this type of discontinuity. The following are important considerations: 1. Interpretation of rounded indications based on codes and standards used in the various sectors of NDT. 2. What types of discontinuities can be regarded as rounded indications? 3. What discontinuity sizes can be regarded as relevant discontinuities? 4. What are the acceptance and rejection criteria for relevant rounded indications 5. Compiling relevant student assignments to facilitate the proper understanding of this aspect.

  7. &apos;&apos;Wie alles sich zum Ganzen webt&apos;&apos;: on a new orientation for the concept of matter, based on relations between quantum physics and cosmology

    Energy Technology Data Exchange (ETDEWEB)

    Goernitz, T. [Inst. fuer Didaktik der Physik, J.W.Goethe-Univ., Frankfurt/Main (Germany)

    2007-07-01

    It is common sense between physicists that in the beginning the cosmos is in a narrow relationship to quantum phenomena. Because of the universal validity of quantum theory this relation remains significant in the whole cosmic evolution. Whereas a classical approach is sufficient for the description of many phenomena it is no more useful at last for the case of the ground state of a system. This holds also for the cosmos. The black holes are that part of physics where quantum theory and gravitational theory come into close contact. There a Gedankenexperiment becomes possible that clarifies the fundamental role of abstract quantum information. We give it a new name (Protyposis) because it must be imagined without emitter, receiver and moreover without any concrete meaning. This meaning-free abstract quantum information is defined by means of black holes and cosmology. Protyposis enables a new conception for &apos;'matter'&apos; and makes possible to overcome the problems of the &apos;'Lego-world-view'&apos;, which result from the attempt to find the &apos;&apos;simple and therefore basic concepts&apos;&apos; in the range of spatial smallness. Matter can be understood now as &apos;&apos;formed and condensed quantum information&apos;&apos;. But on a first view it is nothing to see from its character of being information, as like matter does not appear as &apos;&apos;pure motion&apos;&apos;, what it is also because of E=mc{sup 2}. (orig.)

  8. Tratamento farmacológico do transtorno de estresse pós-traumático

    OpenAIRE

    Bernik Márcio; Laranjeiras Marcionilo; Corregiari Fábio

    2003-01-01

    Os autores apresentam uma revisão de literatura sobre a farmacoterapia do transtorno de estresse pós-traumático (TEPT). Poucos ensaios clínicos controlados já foram feitos nesta área, mas o interesse no transtorno é crescente. Os antidepressivos, especialmente aqueles com atividade serotonérgica, parecem ser tratamentos farmacológicos eficazes no TEPT, seja como tratamento primário ou em associação com a psicoterapia.

  9. &apos;'VaneCAM'&apos; - the third generation of camshaft adjustment systems; &apos;'VaneCAM'&apos; - Nockenwellenversteller der dritten Generation

    Energy Technology Data Exchange (ETDEWEB)

    Knecht, A. [Hydraulik-Ring GmbH, Nuertingen (Germany). Entwicklung Motorentechnik; Stephan, W. [Hydraulik-Ring GmbH, Nuertingen (Germany); Hannibal, W. [Fachhochschule Suedwestfalen, Iserlohn (Germany). Labor fuer Konstruktion und CAE-Anwendungen

    2002-04-01

    Continuously variable camphasers are now well established for modern spark-ignition engines in high-volume production. With the latest generation of camshaft adjustment systems using the vane-type actuator principle, it is possible to move rapidly and reliably through a large adjustment angle. The layout of these adjusting systems is very simple. The production costs are low in comparison to the first generation of camphasers using spur/helical gears to vary the valve timing. The new-generation systems are mechatronic, with the function depending on the coordination and tuning of hydraulic actuation and engine electronics. The term &apos;VaneCAM&apos; is used for the continuously variable systems of this new generation supplied by Hydraulik-Ring in Nuertingen, Germany. (orig.) [German] Stufenlos wirkende Nockenwellenversteller haben sich an modernen Ottomotoren in den letzten Jahren in der Grossserie etabliert. Mit der neuesten Generation von Nockenwellenverstellern, die nach dem Schwenkmotor-Prinzip aufgebaut sind, lassen sich grosse Verdrehwinkel sehr schnell und betriebssicher verstellen. Der Aufbau dieser Versteller ist einfach, und die Herstellkosten sind gering im Vergleich zur ersten Generation von Verstellern. Bei den Systemen der neuen Generation handelt es sich um mechatronische Systeme, deren Funktion von dem Zusammenspiel und der Abstimmung von hydraulischer Ansteuerung und Motorelektronik abhaengt. Mit dem Begriff &apos;VaneCAM&apos; werden die stufenlos wirkenden Systeme dieser neuen Generation von Hydraulik-Ring aus Nuertingen bezeichnet. (orig.)

  10. Conference-debate &apos;When nuclear science provides health care&apos; - Proceedings; conference debat &apos;Quand le nucleaire soigne&apos; - Recueil des presentations

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2012-03-15

    At the occasion of the 2. issue of the &apos;Industry week, the &apos;French society of nuclear energy (SFEN) young generation&apos; and the &apos;Women in Nuclear (WIN)&apos; associations have organised in partnership with Nucleopolis and the Cherbourg-Normandie Techno-pole, a conference day on the topic &apos;why and how nuclear energy is used for cancer therapy&apos;. Professors Jacques Foos, Jean Datchary and Denis Agostini were invited to treat this question. This document is the compilation of their 3 presentations: 1 - The discovery, principle and medical applications of radioactivity (J. Foos, CNAM); 2 - Cancer diagnosis and therapy with nuclear medicine (D. Agostini, CHU Caen); 3 - From diagnosis to therapy: the various radiotherapy methods (J. Datchary)

  11. Sustainable Agriculture: enhancing the &apos;neem cake&apos;

    International Nuclear Information System (INIS)

    Mariani, Susanna

    2015-01-01

    The &apos;neem cake&apos; is the scrap processing of the industrial chain producing neem oil and azadirachtin. The ENEA Technical Unit Environment and Sustainable Development Innovation the Agro-Industrial System, developed a promising experiment to promote the use of &apos;neem cake&apos; as an insecticide, and fertilizer of low cost in sustainable agriculture. [it

  12. Parents&apos; Views of Schools&apos; Involvement Efforts

    Science.gov (United States)

    Rodriguez, Raymond J.; Blatz, Erin T.; Elbaum, Batya

    2014-01-01

    Individual and focus group interviews were conducted with 96 parents of students with disabilities in 18 schools to explore parents&apos; views of schools&apos; efforts to engage them in their child&apos;s education. A mixed-methods approach was used to identify and evaluate the relative importance of eight themes related to schools&apos; efforts…

  13. Fundamental limitations on &apos;warp drive&apos; spacetimes

    Energy Technology Data Exchange (ETDEWEB)

    Lobo, Francisco S N [Centro de Astronomia e AstrofIsica da Universidade de Lisboa, Campo Grande, Ed. C8 1749-016 Lisbon (Portugal); Visser, Matt [School of Mathematical and Computing Sciences, Victoria University of Wellington, PO Box 600, Wellington (New Zealand)

    2004-12-21

    &apos;Warp drive&apos; spacetimes are useful as &apos;gedanken-experiments&apos; that force us to confront the foundations of general relativity, and among other things, to precisely formulate the notion of &apos;superluminal&apos; communication. After carefully formulating the Alcubierre and Natario warp drive spacetimes, and verifying their non-perturbative violation of the classical energy conditions, we consider a more modest question and apply linearized gravity to the weak-field warp drive, testing the energy conditions to first and second orders of the warp-bubble velocity, v. Since we take the warp-bubble velocity to be non-relativistic, v << c, we are not primarily interested in the &apos;superluminal&apos; features of the warp drive. Instead we focus on a secondary feature of the warp drive that has not previously been remarked upon-the warp drive (if it could be built) would be an example of a &apos;reaction-less drive&apos;. For both the Alcubierre and Natario warp drives we find that the occurrence of significant energy condition violations is not just a high-speed effect, but that the violations persist even at arbitrarily low speeds. A particularly interesting feature of this construction is that it is now meaningful to think of placing a finite mass spaceship at the centre of the warp bubble, and then see how the energy in the warp field compares with the mass-energy of the spaceship. There is no hope of doing this in Alcubierre&apos;s original version of the warp field, since by definition the point at the centre of the warp bubble moves on a geodesic and is &apos;massless&apos;. That is, in Alcubierre&apos;s original formalism and in the Natario formalism the spaceship is always treated as a test particle, while in the linearized theory we can treat the spaceship as a finite mass object. For both the Alcubierre and Natario warp drives we find that even at low speeds the net (negative) energy stored in the warp fields must be a significant fraction

  14. CONSERVAÇÃO DE PERAS MINIMAMENTE PROCESSADAS SUBMETIDAS A TRATAMENTOS QUÍMICOS

    OpenAIRE

    BOAS, ANA CAROLINA VILAS; HENRIQUE, PAÔLA DE CASTRO; LIMA, LUIZ CARLOS DE OLIVEIRA; PEREIRA, MICHEL CARDOSO DE ANGELIS

    2015-01-01

    RESUMO O trabalho teve como objetivo testar a eficácia de tratamentos químicos na manutenção da qualidade de peras ‘Williams’ minimamente processadas. Inicialmente, realizaram-se a lavagem, a sanitização e a retirada das sementes dos frutos. Em seguida, foram realizados cortes no formato de palitos, e os mesmos foram imersos nas soluções, compondo os tratamentos: ácido ascórbico a 2 % (controle); ácido ascórbico a 2% + cloreto de cálcio a 2%; ácido ascórbico a 2% + ácido cítrico a 2%; ácido ...

  15. Reconstruction of surface morphology from coherent scattering of &apos;'white'&apos; synchrotron radiation in hard X-ray regime

    Energy Technology Data Exchange (ETDEWEB)

    Sant, Tushar

    2009-07-01

    Energy Dispersive Reflectometry (EDR) beamline at BESSY II provides &apos;'white'&apos; X-rays in the useful energy range of 5apos;'trivial'&apos; samples to determine the so called apparatus function. In addition I measured coherent reflectivity maps from thin film of highly scattering material of Pt with high atom number, Z=78 and patterned semiconducting surface like a GaAs surface grating which provides a certain periodicity in the measured scattering intensity. Finally I measured the surface speckles from a spatially confined Si wafer under the constraint that the size of the sample is smaller than the footprint of the incoming beam at the sample position. To reconstruct surface morphology from coherent reflectivity data is a typical inverse problem. Conventional phase retrieval algorithms like Gerchberg-Saxton (GS) algorithm, error reduction (ER) algorithm, hybrid input-output (HIO) algorithm are used in earlier work by other authors. I modified the conventional GS algorithm and ER algorithm which takes into account the additional Fresnel propagator term and also the illumination function at the sample position. I tested the modified algorithm successfully for a model surface in the form of a surface grating. I used the modified algorithm to reconstruct surface morphology from various static speckle measurements I performed at EDR beamline. The surface profiles reconstructed for different samples from the data at different energies (below the critical energy for the material at a particular incident angle) show almost the same roughness behavior for surface height with mean roughness of {proportional_to}1 nm. With the static speckle data I measured I could retrieve a one-dimensional picture of the sample surface with spatial

  16. &apos;&apos;After the Genome 5 Conference&apos;&apos; to be held October 6-10, 1999 in Jackson Hole, Wyoming

    Energy Technology Data Exchange (ETDEWEB)

    Roger Brent

    1999-10-06

    OAK B139 The postgenomic era is arriving faster than anyone had imagined--sometime during 2000 we&apos;ll have a large fraction of the human genome sequence. Heretofore, our understanding of function has come from non-industrial experiments whose conclusions were largely framed in human language. The advent of large amounts of sequence data, and of &apos;&apos;functional genomic&apos;&apos; data types such as mRNA expression data, have changed this picture. These data share the feature that individual observations and measurements are typically relatively low value adding. Such data is now being generated so rapidly that the amount of information contained in it will surpass the amount of biological information collected by traditional means. It is tantalizing to envision using genomic information to create a quantitative biology with a very strong data component. Unfortunately, we are very early in our understanding of how to &apos;&apos;compute on&apos;&apos; genomic information so as to extract biological knowledge from i t. In fact, some current efforts to come to grips with genomic information often resemble a computer savvy library science, where the most important issues concern categories, classification schemes, and information retrieval. When exploring new libraries, a measure of cataloging and inventory is surely inevitable. However, at some point we will need to move from library science to scholarship.We would like to achieve a quantitative and predictive understanding of biological function. We realize that making the bridge from knowledge of systems to the sets of abstractions that constitute computable entities is not easy. The After the Genome meetings were started in 1995 to help the biological community think about and prepare for the changes in biological research in the face of the oncoming flow of genomic information. The term &apos;&apos;After the Genome&apos;&apos; refers to a future in which complete inventories of the gene products of

  17. Cisto dentígero: modalidades de tratamento

    Directory of Open Access Journals (Sweden)

    Rubens Caliento

    Full Text Available INTRODUÇÃO: O cisto dentígero é o segundo cisto odontogênico mais frequente nos maxilares. É uma lesão benigna, derivada do epitélio odontogênico da coroa de um dente não erupcionado, porém de etiopatogenia incerta. São geralmente radiotransparentes e, mais comumente, uniloculares. Estas lesões são observadas em exames de rotina ou quando não ocorre o irrompimento de um dente permanente. Os terceiros molares inferiores e os caninos superiores são os dentes mais acometidos, sendo também alta a ocorrência desta lesão em dentes supranumerários e associados a odontomas. O cisto dentígero ocorre principalmente nas três primeiras décadas de vida, tendo um crescimento lento e assintomático; pode atingir dimensões consideráveis, causando deformidade facial, impactação e deslocamento de dentes e/ou estruturas adjacentes. OBJETIVO: Definição das técnicas de marsupialização e enucleação, bem como consideração de critérios objetivos importantes para o plano de tratamento, como tamanho do cisto, idade, proximidade com estruturas anatômicas e importância clínica do dente envolvido. Apesar das peculiaridades clínicas de cada caso e do método de tratamento escolhido, o prognóstico destas lesões é favorável, quando se emprega apropriada terapêutica. MATERIAL E MÉTODO: O presente estudo apresentará um relato de caso tratado através da manobra de descompressão seguida de enucleação, bem como uma discussão acerca das modalidades de tratamento. RESULTADO: O paciente encontra-se em pós-operatório de dois anos sem sinais de recidiva da lesão e ausência de parestesias em face. CONCLUSÃO: A técnica empregada preservou a função neurossensorial e mostrou-se eficiente para a cura da lesão.

  18. Tratamento da depressão

    Directory of Open Access Journals (Sweden)

    Fábio Gomes de Matos e Souza

    1999-05-01

    Full Text Available O tratamento antidepressivo deve ser realizado considerando os aspectos biológicos, psicológicos e sociais do paciente. Na média, não há diferenças significativas em termos de eficácia entre os diferentes antidepressivos mas o perfil em termos de efeitos colaterais, preço, risco de suicídio, tolerabilidade varia bastante o que implica em diferenças na efetividade das drogas para cada paciente. A conduta, portanto, deve ser individualizada. A prescrição profilática de antidepressivos irá depender da intensidade e freqüência dos episódios depressivos. O risco de suicídio dever ser sempre avaliado e se necessário o ECT deverá ser indicado. Não há antidepressivo ideal, entretanto, atualmente existe uma disponibilidade grande de drogas atuando através de diferentes mecanismos de ação o que permite que, mesmo em depressões consideradas resistentes, o tratamento possa obter êxito.The antidepressant treatment should be accomplished considering the patient’s biological, psychological and social aspects. In average, there are no significant differences in terms of efficacy among the different antidepressants but the profile in terms of collateral effects, price, suicide risk, tolerability shows great variation which implies in differences in the effectiveness of drugs for each patient. The therapy, therefore, should be individualized. The prophylactic prescription of antidepressants will depend on the intensity and frequency of the depressive episodes. The suicide risk should always be evaluated and if necessary ECT should be prescribed. There is no ideal antidepressant, however, there is a large variety of drugs acting through different mechanisms of action which allows the possibility of therapeutic success in resistant depressions.

  19. The &apos;Energy transition&apos; generation

    International Nuclear Information System (INIS)

    Bedossa, Bastien; Boutignon, Gregoire; Sivy, Corentin; Bercault, Florian; Cage, Agathe; Mahammedi-Bouzina, Mehdi; Potton, Gregoire

    2015-11-01

    The &apos;Cartes sur table&apos; think tank aims at leveraging the opinion of young French people (from 20 to 35 years old) politically leaning to the left, in order to let them become actors in French debates, such as the one on the energy transition policy for a &apos;green growth&apos;. This paper explains the origins and the context of the energy transition policy (the dangers of nuclear power, the high potential of renewable energies, etc.), how to finance the energy transition policy, how to promote energy transition in the daily life (notably in transports and through the struggle against wastage), create a Europe of energy, and so on

  20. The location selection act or &apos;the Emperor&apos;s new clothes&apos;; Das Standortauswahlgesetz oder &apos;Des Kaisers neue Kleider&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Feldmann, Ulrike

    2013-10-15

    As is generally known, the governing parties CDU/CSU and FDP agreed a few weeks ago in the 17{sup th} legislative period of the German Bundestag in a rare show of unanimity, together with the parties SPD and Buendnis 90/Die Gruenen, as well as with the Laender, on a &apos;law to search and select a location for a permanent disposal site for heat-generating radioactive waste products and to change other laws&apos;, in brief a location selection act also called StandAG. The law was received with animated approval from the ranks of the parties - with the exception of the (left-wing) party Die Linke. This praise is a tad bewildering, since the Bundesumweltministerium (Federal Department of the Environment) named solving the task within a single generation as one of the principles for the StandAG, and it was emphasised again and again in the debates about the StandAG that the problem of permanent disposal must not be shifted to the next generation. Conclusion: - The StandAG leads to a postponement of solving the permanent disposal site issue by a least several generations with its predictable, long-winded selection method. - The decision not to explore Gorleben conclusively could lead to the site being permanently (&apos;wasted&apos; or) &apos;burned&apos;. - The de-central, interim disposal site Gorleben is likewise &apos;burned&apos; without having a resilient alternative solution for the glass coquilles that must be taken back. - The people&apos;s protest is exponentiated by the number of the potential sites for the StandAG. - The costs for the alternative site search will not be shifted to the producers of the waste that are obliged by law to deliver the waste because of the financial provisions of the constitution. - The third party protection dogma has not been broken up, which will at least lead to delays in the procedure and will have effects on other major projects in the long run. (orig.)

  1. &apos;Minergie&apos; modernisation - Test in practice; Praxistest Minergie-Modernisierung

    Energy Technology Data Exchange (ETDEWEB)

    Ruetter, H.; Ruetter-Fischbacher, U. [Ruetter und Partner, Soziooekonomische Forschung und Beratung, Rueschlikon (Switzerland); Haessig, W. [Haessig Sustech GmbH - Ingenieurbuero fuer Minergie und nachhaltige Gebaeudetechnik, Uster (Switzerland); Jakob, M. [TEP Energy GmbH, CEPE ETH, Zuerich (Switzerland)

    2008-07-01

    This comprehensive report for the Swiss Federal Office of Energy (SFOE) examines the results obtained in practice concerning the use of the &apos;Minergie&apos; low energy consumption standard. Experience gained with &apos;Minergie&apos; refurbishment projects is reviewed and the critical points and constraints found are discussed. Further, recommendations for improvements in the use of the &apos;Minergie&apos; standard are made. The study is based on questions posed to building owners in the German speaking part of Switzerland who have carried out refurbishment projects to meet &apos;Minergie&apos; standards as well as questions posed to those who did not adhere to &apos;Minergie&apos; standards in the refurbishment of their buildings. The reasons quoted for using / not using the standard are listed and discussed. Possible tightening of energy regulations concerning renovation work are discussed. The recommendations resulting from the survey are also noted and discussed.

  2. Photoluminescence of acupoint &apos;Waiqiu&apos; in human superficial fascia

    Energy Technology Data Exchange (ETDEWEB)

    Zhang Yuan [Synchrotron Radiation Research Center, Department of Physics, Surface Physics Laboratory (State Key Laboratory) of Fudan University, Shanghai 200433 (China); Yan Xiaohui [Synchrotron Radiation Research Center, Department of Physics, Surface Physics Laboratory (State Key Laboratory) of Fudan University, Shanghai 200433 (China); Liu Chenglin [Synchrotron Radiation Research Center, Department of Physics, Surface Physics Laboratory (State Key Laboratory) of Fudan University, Shanghai 200433 (China); Dang Ruishan [Second Military Medical University, Shanghai 200433 (China); Zhang Xinyi [Synchrotron Radiation Research Center, Department of Physics, Surface Physics Laboratory (State Key Laboratory) of Fudan University, Shanghai 200433 (China) and Shanghai Research Center of Acupuncture and Meridian, Pudong, Shanghai 201203 (China)]. E-mail: xy-zhang@fudan.edu.cn

    2006-07-15

    The spectral characters of an acupuncture point named &apos;Waiqiu&apos; in superficial fascia tissue have been studied by photoluminescence (PL) spectroscopy under the excitation of 457.9 nm. The PL around &apos;Waiqiu&apos; acupuncture point consists of two sub-bands resulting from the flavin adenine dinucleotide (FAD) and phospholipids, and the porphyrins (including purine, isoxanthopterin and tryptophan), respectively. More emission due to FAD and phospholipids is found inside the acupuncture effect area of &apos;Waiqiu&apos; than its marginal or outside acupuncture regions. The ratio of emission intensity of FAD and phospholipids to one of porphyrins gradually decreases along the direction away from the center of the acupuncture point. It implies that the component proportion changes between FAD, phospholipids and porphyrins around the &apos;Waiqiu&apos; acupuncture point. We suggest that there might be a certain relationship between redox function of FAD and &apos;Waiqiu&apos; acupuncture effect.

  3. Accidents, &apos;Black Swans&apos; and risk

    Energy Technology Data Exchange (ETDEWEB)

    Luxat, J.C., E-mail: luxatj@mcmaster.ca [McMaster Univ., Dept. of Engineering Physics, Hamilton, Ontario (Canada)

    2013-07-01

    Major accidents and natural disasters with severe consequences have occurred in all sectors of industrial activity with relatively high frequency. The severe consequences of concern involve either significant loss of life or major economic loss, or both loss of life and economic loss. Such events have in the last two years often been referred to as &apos;Black Swan&apos; events following publication of a best-selling book. The events demonstrate limits to the application of Probabilistic Risk Assessment (PRA) that arise from the underlying unquantifiable uncertainty associated with the estimation of the frequency of occurrence of such events. An approach is proposed in this paper that, consistent with the concept of defense in depth employed by the nuclear industry, augments probabilistic risk assessment with a methodology based upon &apos;threat -risk assessment&apos;. This approach shifts these very low frequency, high uncertainty, and high consequence &apos;Black Swan&apos; events out of the probabilistic risk assessment domain and into a deterministic emergency response assessment domain. (author)

  4. Accidents, &apos;Black Swans&apos; and risk

    International Nuclear Information System (INIS)

    Luxat, J.C.

    2013-01-01

    Major accidents and natural disasters with severe consequences have occurred in all sectors of industrial activity with relatively high frequency. The severe consequences of concern involve either significant loss of life or major economic loss, or both loss of life and economic loss. Such events have in the last two years often been referred to as &apos;Black Swan&apos; events following publication of a best-selling book. The events demonstrate limits to the application of Probabilistic Risk Assessment (PRA) that arise from the underlying unquantifiable uncertainty associated with the estimation of the frequency of occurrence of such events. An approach is proposed in this paper that, consistent with the concept of defense in depth employed by the nuclear industry, augments probabilistic risk assessment with a methodology based upon &apos;threat -risk assessment&apos;. This approach shifts these very low frequency, high uncertainty, and high consequence &apos;Black Swan&apos; events out of the probabilistic risk assessment domain and into a deterministic emergency response assessment domain. (author)

  5. DGMK spring meeting of the &apos;Exploration and Production&apos; department. Authors&apos; manuscripts; DGMK-Fruehjahrstagung des Fachbereichs &apos;Aufsuchung und Gewinnung&apos;. Autorenmanuskripte

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-07-01

    The spring meeting of the Deutsche Wissenschaftliche Gesellschaft fuer Erdoel, Erdgas und Kohle e.V. focused on exploration and production. Papers were presented on exploration and production in general, geology, deposit development, extraction of petroleum/natural gas, drilling, underground storage, geophysics and geochemistry. [German] Die Fruehjahrstagung der Deutschen Wissenschaftlichen Gesellschaft fuer Erdoel, Erdgas und Kohle e.V. wurde vom Fachbereich &apos;&apos;Aufsuchung und Gewinnung&apos;&apos; bestimmt. Die Vortraege beschaeftigten sich mit den Gebieten Exploration and Production allgemein, Geologie, Lagerstaettentechnik, Foerdertechnik fuer Erdoel/Erdgas, Bohrtechnik, Untertagesspeichertechnik, Geophysik und Geochemie.

  6. Resource consumption of Germany - indicators and definitions. Development of a glossary on the concept of &apos;'resources'&apos; and calculation of missing characteristic data of resources consumption for further political analysis; Ressourcenverbrauch von Deutschland - aktuelle Kennzahlen und Begriffsbestimmungen. Erstellung eines Glossars zum &apos;'Ressourcenbegriff'&apos; und Berechnung von fehlenden Kennzahlen des Ressourcenverbrauchs fuer die weitere politische Analyse

    Energy Technology Data Exchange (ETDEWEB)

    Schuetz, Helmut; Bringezu, Stefan [Wuppertal Institut fuer Klima, Umwelt, Energie GmbH, Wuppertal (Germany). Forschungsgruppe 3: Stoffstroeme und Ressourcenmanagement

    2008-02-15

    The goals of the reported study are: - to prepare a glossary on the term &apos;'Resources'&apos; in order to support communication based on a harmonised resource term and associated terms and - to provide key data on resource use in Germany in time series since 1991 up to the most recent year for which data were available (2004 in general), and to attribute results to the resource terms. Results achieved are presented and discussed below by the following sections: Provision of a glossary on the term &apos;'resource'&apos;, use of the term &apos;'resource'&apos; at different levels, and provision of data and derived indicators for resource consumption in time series. First, a list of the relevant publications in the topic field &apos;'resources'&apos; was provided and co-ordinated with the client. This publication list is given in the annex to this report. On basis of national and international sources a glossary was provided which clearly describes and comments the resource term, its sub-terms and associated terms. This glossary is in the annex to this report. (orig.)

  7. KONTEC 2013. 11{sup th} international symposium on &apos;Conditioning of radioactive operational and decommissioning waste&apos; and 11{sup th} BMBF status report on &apos;Decommissioning and demolition of nuclear facilities&apos;; KONTEC 2013. 11. internationales Symposium &apos;Konditionierung radioaktiver Betriebs- und Stilllegungsabfaelle&apos; einschliesslich 11. Statusbericht des BMBF &apos;Stilllegung und Rueckbau kerntechnischer Anlagen&apos;. Veranstaltungsbericht

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2013-06-15

    KONTEC 2013 was held in Dresden on 13 to 15 March 2013. The 11{sup th} event organized under this heading dealt with the subjects of &apos;Conditioning of Radioactive Operational and Decommissioning Waste&apos; and &apos;Decommissioning and Demolition of Nuclear Facilities&apos; including the R and D Status Report by the Federal Ministry of Education and Research (BMBF) on the same subject. The conference was attended by an international audience from 19 countries. The program included plenary sessions on these 4 key topics: - Disposal of Radioactive Residues from Nuclear Facilities&apos; Operation and Decommissioning. - Decommissioning and Dismantling of Nuclear Facilities. - Facilities and Systems for the Conditioning of Operational and Decommissioning Wastes. - Transport, Interim and Final Storage of Non-heat Generating Wastes (i.e. Konrad). These sessions were accompanied by poster sessions and short presentations under the heading of &apos;Kontec Direct.&apos; The best presentations of the categories Plenary Session Presentation, Poster Presentation and Kontec-Direct have been awarded. In detail, &apos;Dismantling of Russian nuclear powered submarines&apos; by Detlef Mietann, &apos;Requalification of &apos;Old Packages&apos; for the Konrad Repository Described for the Model Case of Packages from Storage Annex A and Repackaging of Containers Holding Compacts in Hall 2 of the GNS Plant&apos; by Martina Koessler, Sebastian Schwall and Pascal Budriks, and &apos;Electrochemical process development for cleaning organic, C-14-labelled waste solutions&apos; by Hans-Juergen Friedrich. (orig.)

  8. Proposal of a simple screening method for a rapid preliminary evaluation of &apos;&apos;heavy metals&apos;&apos; mobility in soils of contaminated sites

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Valentina; Chiusolo, Francesca; Cremisini, Carlo [ENEA - Italian Agency for New Technologies, Energy and Environment, Rome (Italy). Section PROTCHIM

    2010-09-15

    Risks associated to &apos;&apos;heavy metals&apos;&apos; (HM) soil contamination depend not only on their total content but, mostly, on their mobility. Many extraction procedures have been developed to evaluate HM mobility in contaminated soils, but they are generally time consuming (especially the sequential extraction procedures (SEPs)) and consequently applicable on a limited number of samples. For this reason, a simple screening method, applicable even &apos;&apos;in field&apos;&apos;, has been proposed in order to obtain a rapid evaluation of HM mobility in polluted soils, mainly focused on the fraction associated to Fe and Mn oxide/hydroxides. A buffer solution of trisodium citrate and hydroxylamine hydrochloride was used as extractant for a single-step leaching test. The choice of this buffered solution was strictly related to the possibility of directly determining, via titration with dithizone (DZ), the content of Zn, Cu, Pb and Cd, which are among the most representative contaminants in highly mineralised soils. Moreover, the extraction solution is similar, aside from for the pH value, which is the one used in the BCR SEP second step. The analysis of bivalents ions through DZ titration was exploited in order to further simplify and quicken the whole procedure. The proposed method generically measures, in few minutes, the concentration of total extractable &apos;&apos;heavy metals&apos;&apos; expressed as molL{sup -1} without distinguishing between elements. The proposed screening method has been developed and applied on soil samples collected from rural, urban and mining areas, representing different situation of soil contamination. Results were compared with data obtained from the BCR procedure. The screening method demonstrated to be a reliable tool for a rapid evaluation of metals mobility. Therefore, it could be very useful, even &apos;&apos;in field&apos;&apos;, both to guide the sampling activity on site and to monitor the efficacy of the subsequent

  9. Tratamento cirúrgico da litíase vesical: revisão de literatura

    Directory of Open Access Journals (Sweden)

    Fabio Cesar Miranda Torricelli

    Full Text Available Cálculos vesicais são raros e a maioria dos casos ocorre em homens adultos com obstrução infravesical. Atualmente, existem poucos dados sobre o melhor tratamento desta doença. O objetivo desta revisão foi discutir alguns aspectos da patogênese e abordar o tratamento da litíase vesical. Uma ampla pesquisa na base de dados da "National Library of Medicine"/Pubmed foi realizada com os seguintes unitermos e descritores: vesical ou bexiga associados a cálculo, pedra ou litíase, e cistolitotripsia. Cento e setenta e um artigos foram identificados. Os artigos foram avaliados independentemente por dois revisores com experiência em urolitíase. Foram incluídos quando os resultados, complicações e seguimento foram claramente reportados. No final, 32 estudos preencheram os critérios de inclusão. Nota-se que diversas opções para o tratamento da litíase vesical estão disponíveis, porém não há estudos randomizados comparando-as. Diferentes taxas de pacientes livres de cálculo são descritas, sendo: litotripsia extracorpórea com ondas de choque (75-100%, cistolitotripsia transureteroscópica (63-100%, cistolitotripsia percutânea (89-100% e cirurgia aberta (100%. O acesso percutâneo apresenta menor morbidade com resultados semelhantes ao tratamento transuretral, enquanto a litotrispsia extracorpórea apresenta as menores de taxas de eliminação de cálculos e fica reservada aos pacientes de alto risco cirúrgico.

  10. Energia solar no tratamento de corante têxtil

    Directory of Open Access Journals (Sweden)

    Viviane Farias Silva

    2014-10-01

    Full Text Available As indústrias utilizam a água em todo o seu processo, desperdiçando enormes volumes de água gerando efluentes com altos índices de produtos químicos, precisando de tratamento para ser reutilizado ou lançado no meio ambiente. Nesse contexto, o presente trabalho foi realizado no Laboratório de Engenharia Ambiental e de Qualidade na Universidade Federal de Pernambuco objetivando-se a degradação de corante utilizados nas indústrias têxtis através do uso da energia solar como alternativa de tratamento de efluente. Nesta pesquisa os testes fotocatalíticos foram realizados com o catalisador em pó (TiO2 - P25, contendo o corante têxtil Remazol Amarelo Ouro RNL (RGY ou sem catalisador nos testes de fotólise. Foram testados dois tipos de radiação, a artificial e a energia solar (natural. Para avaliar a descoloração e a degradação das amostras, a Espectroscopia UV-visível foi a principal técnica analítica empregada como também realizadas análises de Carbono Orgânico Total (COT e Demanda Química de Oxigênio (DQO. Nas 6 (seis analises realizadas obteve-se um elevado índice de remoção da cor do corante, superior a 97%, com alta eficiência do processo com uma significativa redução da COT e da DQO. Os métodos utilizados foram eficientes na descoloração do RGY, como também na sua degradação, tornando-se uma técnica inovadora com o uso da energia solar para o tratamento de efluentes têxteis.Palavras-chave: efluente industrial, alternativa sustentável, degradação do remazol amarelo ouro, descoloração de efluente

  11. Tratamento cirúrgico do megaesôfago recidivado

    Directory of Open Access Journals (Sweden)

    José Luiz Braga de Aquino

    Full Text Available OBJETIVO: Avaliar os resultados do tratamento cirúrgico em uma série de pacientes submetidos ao tratamento prévio para megaesôfago que evoluíram com recidiva de sintomas. MÉTODO: Analisou-se os resultados das diversas técnicas operatórias realizadas em 47 pacientes pelo Serviços de Cirurgia Geral e Torácica do HMCP-PUC-Campinas. A morbidade pós-cirúrgica, mortalidade, o alívio ou nova recidiva de sintomas e o tempo de seguimento foram os principais indicadores. Dividiu-se a série em três grupos, de acordo com o grau da afecção: Incipiente (nove casos, Não-avançado (18 casos e avançado (20 casos. As técnicas operatórias utilizadas foram: à cardiomiectomia com fundoplicatura anterior, esofagocardioplastia à Tahl, esofagocardioplastia à Serra-Dória, Esofagectomia Subtotal e Mucosectomia com conservação da túnica muscular esofágica. RESULTADOS: Obteve-se índices de resolutividade satisfatórios com a técnica de cardiomiectomia com fundoplicatura para o megaesôfago Incipiente, com baixa morbidade. Nos megaesôfago não-avançado, as cardiopatias, em especial a esofagocardioplastia à Serra-Dória mostram se mais adequadas. A terapêutica do megaesôfago avançado apresentou as maiores taxas de morbidade e demonstrou superioridade das técnicas mais agressivas em relação às técnicas conservadoras, em especial a mucosectomia com preservação da túnica muscular, sendo esta a técnica com menor morbidade dentro do grupo avançado. CONCLUSÃO: A difícil padronização do tratamento cirúrgico do megaesôfago recidivado deve-se às inúmeras técnicas disponíveis, às habilidades pessoais dos cirurgiões e atenta para a criação de protocolos terapêuticos.

  12. Einstein-Rosen &apos;bridge&apos; revisited and lightlike thin-shell wormholes

    International Nuclear Information System (INIS)

    Guendelman, E.; Nissimov, E.; Pacheva, S.; Stoilov, M.

    2017-01-01

    We study in some detail the properties of the mathematically correct formulation of the classical Einstein-Rosen &apos;bridge&apos; as proposed in the original 1935 paper, which was shown in a series of previous papers of ours to represent the simplest example of a static spherically symmetric traversable lightlike thin-shell wormhole. Thus, the original Einstein-Rosen &apos;bridge&apos; is not equivalent to the concept of the dynamical and non-traversable Schwarzschild wormhole, also called &apos;Einstein-Rosen bridge&apos; in modern textbooks on general relativity. The original Einstein-Rosen &apos;bridge&apos; requires the presence of a special kind of &apos;exotic&apos; matter source located on its throat which was shown to be the simplest member of the previously introduced by us class of lightlike membranes. We introduce and exploit the Kruskal-Penrose description of the original Einstein-Rosen &apos;bridge&apos;. In particular, we explicitly construct closed timelike geodesics on the pertinent Kruskal-Penrose manifold.

  13. &apos;Bluetooth&apos; for radio-connecting short distance; Kinkyori wo musen setsuzokusuru &apos;Bluetooth&apos;

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    &apos;Bluetooth&apos; is a new connection method for radio-connecting a short distance by means of mobile equipment including a note PC, PC peripheral equipment and portable telephone, using 2.4GHz ISM (Industrial Scientific Medical) band. It is capable of making a network without a complex operation, enabling data and audio communications. In May, 1998, an operation for deciding on the specifications was started under the leadership of five companies consisting of Ericsson, Nokia, Intel, IBM and Toshiba, with the specification version 1.0 completed in July, 1999 and opened to the public. (readable on http://www.bluetooth.com). Using such features as low power consumption, low cost and small size, the &apos;Bluetooth&apos; will be mounted on various kinds of mobile equipment and developed in mobile PAN (Personal Area Network). (translated by NEDO)

  14. Vertiefungskurs 2014. Safety margins in nuclear power plants. Identify, quantify and extend; Vertiefungskurs 2014 zum Thema &apos;&apos;Sicherheitsmargen in Kernkraftwerken. Identifizieren, quantifizieren, erweitern&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Rey, Matthias

    2015-02-15

    Fifteen speakers dealt with the topic safety margins in nuclear power plants from different points of view at the &apos;&apos;Vertiefungskurs 2014&apos;&apos; of the Nuklearforum Schweiz in Olten, 4 and 5 November 2014. In the context of the &apos;&apos;Vertiefungskurs 2014&apos;&apos; the safety margins in power plants were considered and quantified and possible extensions have been discussed. The conference started with an in-depth introduction of the basis design of existing nuclear power plants. Thereafter speakers told about the main topics emergency preparedness, knowledge management and safety retrofit of nuclear power plants in operation.

  15. MID-INFRARED HIGH-CONTRAST IMAGING OF HD 114174 B: AN APPARENT AGE DISCREPANCY IN A &apos;'SIRIUS-LIKE'&apos; BINARY SYSTEM

    Energy Technology Data Exchange (ETDEWEB)

    Matthews, Christopher T.; Crepp, Justin R. [Department of Physics, University of Notre Dame, 225 Nieuwland Science Hall, Notre Dame, IN 46556 (United States); Skemer, Andrew; Hinz, Philip M.; Bailey, Vanessa P.; Defrere, Denis; Leisenring, Jarron [Department of Astronomy, University of Arizona, 993 N. Cherry Ave, Tucson, AZ 85721 (United States); Gianninas, Alexandros; Kilic, Mukremin [Department of Physics and Astronomy, University of Oklahoma, Norman, OK 73019 (United States); Skrutskie, Michael [Department of Astronomy, University of Virginia, Charlottesville, VA 22904 (United States); Esposito, Simone; Puglisi, Alfio [Istituto Nazionale di Astrofisica, Osservatorio Astrofisico di Arcetri Largo E. Fermi I-550125 Firenze (Italy)

    2014-03-10

    We present new observations of the faint &apos;'Sirius-like'&apos; companion discovered to orbit HD 114174. Previous attempts to image HD 114174 B at mid-infrared wavelengths using NIRC2 at Keck have resulted in a non-detection. Our new L&apos;-band observations taken with the Large Binocular Telescope and L/M-band InfraRed Camera recover the companion (ΔL = 10.15 ± 0.15 mag, ρ = 0.&apos;&apos;675 ± 0.&apos;&apos;016) with a high signal-to-noise ratio (10σ). This measurement represents the deepest L&apos; high-contrast imaging detection at subarcsecond separations to date, including extrasolar planets. We confirm that HD 114174 B has near-infrared colors consistent with the interpretation of a cool white dwarf (WD; J – L&apos; = 0.76 ± 0.19 mag, K – L&apos; = 0.64 ± 0.20). New model fits to the object&apos;s spectral energy distribution indicate a temperature T {sub eff} = 4260 ± 360 K, surface gravity log g = 7.94 ± 0.03, a cooling age t{sub c} ≈ 7.8 Gyr, and mass M = 0.54 ± 0.01 M {sub ☉}. We find that the cooling ages given by theoretical atmospheric models do not agree with the age of HD 114174 A derived from both isochronological and gyrochronological analyses. We speculate on possible scenarios to explain the apparent age discrepancy between the primary and secondary. HD 114174 B is a nearby benchmark WD that will ultimately enable a dynamical mass estimate through continued Doppler and astrometric monitoring. Efforts to characterize its physical properties in detail will test theoretical atmospheric models and improve our understanding of WD evolution, cooling, and progenitor masses.

  16. Differential response of the skin in young and old rats to a combination of X-rays and &apos;wet&apos; or &apos;dry&apos; hyperthermia

    Energy Technology Data Exchange (ETDEWEB)

    Hamlet, R.; Hopewell, J.W.

    1986-11-01

    Hind feet of group of female rats aged 7, 14 and 52 weeks were X-irradiated at 20, 25 or 30 Gy. Hyperthermia (42.5/sup 0/C for 1 h) was carried out immediately following irradiation using either &apos;wet&apos; or &apos;dry&apos; heat, by immersion in water or fluorocarbon liquid. Results demonstrated that &apos;wet&apos; heat produced a consistently greater enhancement of the irradiation damage than &apos;dry&apos;. The thermal enhancement ratio for irradiation plus &apos;wet&apos; heat was approximately 1.5 and for irradiation plus &apos;dry&apos; heat 1.17 to 1.39. Immersion of the feet in fluorocarbon liquid at 37/sup 0/C did not significantly modify the irradiation response of the skin. The lower thermal enhancement ratios obtained using immersion in fluorocarbon liquid at 42.5/sup 0/C are close to those obtained in large animal studies and similar to the limited amount of data from clinical studies where microwave or ultrasound heating techniques were used. It has been demonstrated that there are large age-related differences in the response of the rat foot skin to irradiation alone. It has also been shown, using rats of the same age, that the response to irradiation plus hyperthermia was less age dependent.

  17. OBJECTIVE BAYESIAN ANALYSIS OF &apos;'ON/OFF'&apos; MEASUREMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Casadei, Diego, E-mail: diego.casadei@fhnw.ch [Visiting Scientist, Department of Physics and Astronomy, UCL, Gower Street, London WC1E 6BT (United Kingdom)

    2015-01-01

    In high-energy astrophysics, it is common practice to account for the background overlaid with counts from the source of interest with the help of auxiliary measurements carried out by pointing off-source. In this &apos;'on/off'&apos; measurement, one knows the number of photons detected while pointing toward the source, the number of photons collected while pointing away from the source, and how to estimate the background counts in the source region from the flux observed in the auxiliary measurements. For very faint sources, the number of photons detected is so low that the approximations that hold asymptotically are not valid. On the other hand, an analytical solution exists for the Bayesian statistical inference, which is valid at low and high counts. Here we illustrate the objective Bayesian solution based on the reference posterior and compare the result with the approach very recently proposed by Knoetig, and discuss its most delicate points. In addition, we propose to compute the significance of the excess with respect to the background-only expectation with a method that is able to account for any uncertainty on the background and is valid for any photon count. This method is compared to the widely used significance formula by Li and Ma, which is based on asymptotic properties.

  18. Teriparatida (PTH[1-34]rh: uma nova perspectiva no tratamento da osteoporose

    Directory of Open Access Journals (Sweden)

    Oliveira Juliana Helena Abreu de

    2003-01-01

    Full Text Available No momento, as medicações aprovadas para tratamento da osteoporose agem reduzindo a taxa de perda óssea e diminuindo a reabsorção óssea. A teriparatida é um fragmento recombinante sintético de 34 aminoácidos do hormônio paratireóide humano. A teriparatida se liga ao receptor de PTH da proteína G e estimula a formação e a ação dos osteoblastos, que são as células responsáveis pela formação dos ossos. Assim, a principal diferença entre o tratamento da osteoporose com teriparatida e o tratamento anti-reabsorção é que a teriparatida promove o crescimento de osso novo. Em estudos pré-clínicos, o uso intermitente de PTH foi associado com um aumento significativo da massa óssea gradeada em diversos locais. A exposição intermitente ao PTH durante 4 a 6 semanas em modelos de animais ovariectomizados leva a um aumento da espessura do osso gradeado. Há estudos clínicos que mostram que a teriparatida aumenta significativamente a densidade óssea e diminui a incidência de fraturas osteoporóticas vertebrais e não-vertebrais nas mulheres com osteoporose pós-menopáusica e têm risco alto de fratura, e aumenta a densidade óssea nos homens com osteoporose, tanto hipogonádica como idiopática. A teriparatida é dada por injeção subcutânea diária e foi associada com um mínimo de efeitos colaterais, além de não apresentar interações medicamentosas. Sendo assim, a teriparatida surge como uma abordagem completamente nova no tratamento da osteoporose, estimulando diretamente a formação do osso.

  19. Efetividade do tratamento da tuberculose Effectiveness of tuberculosis treatment

    Directory of Open Access Journals (Sweden)

    Letícia Nazareth Fernandes da Paz

    2012-08-01

    Full Text Available OBJETIVO: Analisar as estratégias que influenciam a efetividade do tratamento da tuberculose em Unidades Básicas de Saúde (UBS. MÉTODOS: Levantamento epidemiológico, descritivo, retrospectivo, envolvendo os prontuários médicos de 588 pacientes com tuberculose cadastrados no programa de controle da tuberculose, entre janeiro de 2004 e dezembro de 2008, em duas UBS - Centro de Saúde Escola do Marco (CSEM e UBS da Pedreira (UBSP - localizadas na cidade de Belém (PA. Os critérios de exclusão foram ter idade 59 anos e ter alta por transferência ou mudança de diagnóstico. Os dados coletados foram idade, sexo, tipo de tratamento (autoadministrado ou supervisionado, coinfecção por HIV e desfecho do tratamento. Os profissionais de saúde envolvidos no programa da tuberculose das duas UBS foram entrevistados quanto às estratégias utilizadas no controle da doença e à rotina de atendimento. RESULTADOS: Não houve diferenças significativas quanto a idade, sexo e coinfecção com HIV nas duas UBS. A utilização de tratamento supervisionado foi significativamente maior no CSEM que na UBSP, assim como a taxa de cura, enquanto a taxa de abandono foi maior na UBSP que no CSEM. CONCLUSÕES: Para pacientes cadastrados em programas de controle da tuberculose em UBS no Brasil, o tratamento supervisionado provavelmente é uma estratégia de extrema importância para se alcançar uma menor taxa de abandono.OBJECTIVE: To analyze the treatment strategies that influence the effectiveness of tuberculosis treatment at primary care clinics (PCCs in Brazil. METHODS: This was a descriptive, retrospective epidemiological survey based on the medical records of 588 tuberculosis patients enrolled in the tuberculosis control programs at two PCCs located in the city of Belém, Brazil: Centro de Saúde Escola do Marco (CSEM and Unidade Básica de Saúde da Pedreira (UBSP. The survey was limited to patients enrolled between January of 2004 and December of 2008

  20. Tratamento de erros inatos do metabolismo Treatment of inborn errors of metabolism

    Directory of Open Access Journals (Sweden)

    Ida Vanessa Schwartz

    2008-08-01

    Full Text Available OBJETIVO: Esta revisão teve por objetivo abordar a situação atual do tratamento dos distúrbios do metabolismo intermediário (principalmente dos aminoácidos, ciclo da uréia e ácidos orgânicos e das doenças relacionadas a duas organelas subcelulares (lisossomos e peroxissomos. FONTES DOS DADOS: Na abordagem do tratamento dos distúrbios do metabolismo intermediário, foi dada prioridade às principais formas de manejo da intoxicação, em virtude da importância para o pediatra do tratamento de quadros agudos e com risco de vida. O artigo apresenta também uma visão geral do tratamento das doenças lisossômicas e peroxissômicas, com ênfase na terapia de reposição enzimática, uma modalidade de tratamento de uso crescente com a qual o pediatra deve se familiarizar. SÍNTESE DOS DADOS: As principais medidas para manejo da intoxicação presente em muitos erros inatos do metabolismo intermediário foram apresentadas (restrição de aporte de substrato através da dieta ou através de inibição enzimática, remoção do produto tóxico, estímulo da atividade enzimática residual, reposição do produto deficiente. O material elaborado sobre terapia para doenças lisossômicas e peroxissômicas inclui tabelas informativas sobre os tratamentos disponíveis. CONCLUSÕES: O tratamento dos erros inatos do metabolismo é uma situação complexa e que deve ser abordada por uma equipe multidisciplinar, na qual o pediatra é peça-chave. Este capítulo contém informações práticas relativas ao manejo de alguns erros inatos do metabolismo e proporciona ao pediatra uma visão geral dos desenvolvimentos recentes ocorrido nessa área da medicina.OBJECTIVE: To describe the current state of treatment for disorders of intermediate metabolism (primarily of amino acids, urea cycle and organic acids and for diseases related to two subcellular organelles (lysosomes and peroxisomes. SOURCES: In covering the treatment of disorders of intermediate

  1. A neural model for transient identification in dynamic processes with &apos;don&apos;t know&apos; response

    Energy Technology Data Exchange (ETDEWEB)

    Mol, Antonio C. de A. E-mail: mol@ien.gov.br; Martinez, Aquilino S. E-mail: aquilino@lmp.ufrj.br; Schirru, Roberto E-mail: schirru@lmp.ufrj.br

    2003-09-01

    This work presents an approach for neural network based transient identification which allows either dynamic identification or a &apos;don&apos;t know&apos; response. The approach uses two &apos;jump&apos; multilayer neural networks (NN) trained with the backpropagation algorithm. The &apos;jump&apos; network is used because it is useful to dealing with very complex patterns, which is the case of the space of the state variables during some abnormal events. The first one is responsible for the dynamic identification. This NN uses, as input, a short set (in a moving time window) of recent measurements of each variable avoiding the necessity of using starting events. The other one is used to validate the instantaneous identification (from the first net) through the validation of each variable. This net is responsible for allowing the system to provide a &apos;don&apos;t know&apos; response. In order to validate the method, a Nuclear Power Plant (NPP) transient identification problem comprising 15 postulated accidents, simulated for a pressurized water reactor (PWR), was proposed in the validation process it has been considered noisy data in order to evaluate the method robustness. Obtained results reveal the ability of the method in dealing with both dynamic identification of transients and correct &apos;don&apos;t know&apos; response. Another important point studied in this work is that the system has shown to be independent of a trigger signal which indicates the beginning of the transient, thus making it robust in relation to this limitation.

  2. Câncer do colo de útero: efeitos do tratamento

    Directory of Open Access Journals (Sweden)

    Letícia Fernandez Frigo

    2015-12-01

    Full Text Available O Câncer incide sobre a população de forma avassaladora, em função da transição demográfica, bem como do aumento da exposição da população a agentes cancerígenos no meio ambiente. O câncer de colo de útero é a segunda neoplasia mais comum entre as mulheres. As modalidades terapêuticas, no decorrer de suas aplicações, levam a diversas disfunções uroginecológicas consequentes dos procedimentos cirúrgicos e demais terapias. Objetivo: investigar a ocorrência de disfunções uroginecológicas, após o tratamento do câncer de colo de útero. Método: a pesquisa desenvolvida foi do tipo, descritiva com abordagem quantitativa, sendo do tipo não probabilística acidental. Participaram da pesquisa nove mulheres no período climatérico, que realizaram tratamento do câncer do colo de útero cirúrgico ou conservador há, no máximo, cinco anos. Foi aplicado a ficha de avaliação e o inventário de satisfação sexual. Resultado: verificou-se, através dos dados, que a radioterapia foi o tratamento mais utilizado entre as participantes. Pode-se verificar que o Câncer de colo de útero acarreta algumas disfunções uroginecológica em mulheres portadoras desta patologia. Considerações finais: neste estudo, pode-se analisar os efeitos que o Câncer de colo de útero acarretou nas participantes desta pesquisa, ocasionando algumas disfunções como dispareunia, estenose, vaginismo, diminuição da lubrificação, incontinência urinária, incontinência fecal e linfedema.

  3. The &apos;&apos;Hybrid Effect&apos;&apos;. Influence of hybridisation on the durability of automatic transmissions; Der &apos;'Hybrid-Effekt'&apos;. Einfluss der Hybridisierung auf die Lebensdauer von Automatikgetrieben

    Energy Technology Data Exchange (ETDEWEB)

    Lavall, Thomas [ZF Getriebe GmbH, Friedrichshafen (Germany)

    2009-07-01

    The series development of hybrid systems in combination with the new ZF 8-speed automatic transmissions contains also for the testing several aspects of challenge the complex overall system with additional loads, components and functions requires new definitions of testing volumes and load collectives with an ideal integration of testing expertise of all parties involved. This paper describes how, already in an early development stage of the fully hybridised 8-speed transmission system, specific load collectives have been developed with the aid of simulation. So the &apos;'hybrid-effect'&apos; as an additional load and its influence on the durability compared to non hybridised applications could be identified. Also it is shown how testing collectives have been adapted in practice to the hybrid specific needs to the point of a specific assembly of a test bench. The ZF testing concept for hybridised automatic transmissions has the ability of an early and efficient verification of the production readiness also securing highest possible series production quality for prospective hybrid projects. (orig.)

  4. Computerized axial tomography of the chest for visualization of &apos;'absent'&apos; pulmonary arteries

    Energy Technology Data Exchange (ETDEWEB)

    Sondheimer, H.M. (Upstate Medical Center, Syracuse, NY); Oliphant, M.; Schneider, B.; Kavey, R.E.W.; Blackman, M.S.; Parker, F.B. Jr.

    1982-05-01

    To expand the search for central pulmonary arteries in six patients with absence of cardiac-pulmonary continuity, computerized axial tomography (CAT) of the chest was performed. The CAT scans were compared with previous arteriograms and pulmonary vein wedge angiograms. Three patients with type IV truncus arteriosus were studied, and none had a central, right or left pulmonary artery on CAT scan. However, two patients with tetralogy of Fallot with pulmonary atresia and a patent ductus arteriosus to the right lung demonstrated the presence of a left pulmonary artery. In addition, one child with truncus arteriosus with &apos;'absent'&apos; left pulmonary artery demonstrated a left pulmonary artery on the CAT scan. The CAT scan may therefore enhance our ability to search for disconnected pulmonary arteries in children with complex cyanotic congenital heart disease.

  5. Technical and quality requisites (RTC&apos;s) &apos;a data architecture&apos;; Requisitos tecnicos y de calidad (RTC&apos; s) &apos;una arquitectura de datos&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Munoz G, R.; Jimenez R, B.; Ahedo A, S. [ININ, 52750 La Marquesa, Estado de Mexico (Mexico)]. e-mail: rmg@nuclear.inin.mx

    2007-07-01

    The RTC&apos;s are notes of technical and of quality requisites that the CLV emits, according to validity procedures of the Nuclear power station, to specify purchasing requisites of equipment with quality assurance category. This document contains a description of the computer program application RTC&apos;s, elaborated by the ININ for the CLV that allows to capture and to process the information of a database whose purpose is to facilitate the elaboration of the RTC&apos;s. Details of its development process are included. (Author)

  6. Synthesis of (+-)-(1,1&apos;- sup 15 N sub 2 , 2&apos;- sup 13 C)-trans-3&apos;-methylnicotine

    Energy Technology Data Exchange (ETDEWEB)

    Sirimanne, S.R.; Maggio, V.L.; Patterson, D.G. Jr. (Department of Health and Human Services, Atlanta, GA (United States))

    1992-03-01

    The synthesis of ({+-})- (1,1&apos;-{sup 15}N{sub 2}, 2&apos;-{sup 13}C)-trans-3&apos;-methylnicotine is reported. {sup 15}N-3-Bromopyridine obtained from bromination of pyridine was formylated with nBuLi/(carbonyl-{sup 13}C)-methyl formate. The resulting {sup 15}n-Pyridine-3-({sup 13}C-carbonyl)-carboxaldehyde was reacted with {sup 15}N-methylamine and then the resulting Schiff&apos;s base was condensed with succinic anhydride to give ({+-})- (1,1&apos;-{sup 15}N{sub 2}, 5&apos;-{sup 13}C)-trans-4&apos;-carboxycotinine. Reduction with lithium aluminum hydride and mesylation followed by reduction with Zn/NaI gave ({+-})-(1,1&apos;-{sup 15}N{sub 2}, 2&apos;-{sup 13}C)-trans-3&apos;-methylnicotine. (Author).

  7. Eficácia dos tratamentos estabelecidos pelo Manual da IETS, em oócitos, expostos à Leptospira interrogans

    Directory of Open Access Journals (Sweden)

    A.C. Goes

    2012-02-01

    Full Text Available Avaliou-se a eficácia dos tratamentos, definidos pela International Embryo Transfer Society (IETS, de oócitos bovinos, maturados in vitro e expostos experimentalmente à Leptospira interrogans sorovar Grippotyphosa. Os oócitos foram obtidos por meio de punção folicular, selecionados e distribuídos em quatro grupos, expostos ao patógeno e submetidos aos diferentes tipos de tratamentos. Foram expostos à cepa na concentração de 4,7.10(5/µL, virulenta e não adaptada ao meio de manutenção EMJH, e, de 6,3.10(5/µL, avirulenta e adaptada ao meio, por 24 horas. Os grupos tratados com tripsina ou antibióticos apresentaram eficácia de 21,7%, e o grupo lavado sequencialmente 33,4%. Os tratamentos não foram eficazes para os contaminados com a cepa avirulenta. Concluiu-se que as normas de controle de qualidade estabelecidas pela IETS poderiam ser revisadas e, possivelmente, redefinidas, uma vez que a eficácia dos tratamentos, provavelmente, não depende somente da espécie do patógeno, pois há interferência da virulência e de ação dos tratamentos sobre o tipo de patógeno.

  8. Studies on the Interaction of a Novel 6,6&apos;&apos;-bis(1,2,4-triazin-3-yl)- 2,2&apos;:6&apos;,2&apos;&apos;-terpyridine Ligand with Lanthanide(III) Ions and Americium(III)

    International Nuclear Information System (INIS)

    Lewis, Frank W.; Harwood, Laurence M.; Hudson, Michael J.; Drew, Michael G.B.; Modolo, Giuseppe; Sypula, Michal; Desreux, Jean F.; Bouslimani, Nouri; Vidick, Geoffrey

    2010-01-01

    The new solvent extraction reagent 6,6&apos;&apos;-bis(5,5,8,8-tetramethyl- 5,6,7,8-tetrahydro-1,2,4-benzo-triazin-3-yl)-2,2&apos;:6&apos;,2&apos;&apos;-terpyridine (CyMe 4 -BTTP) has been synthesized in 4 steps from 2,2&apos;:6&apos;,2&apos;&apos;-terpyridine. Detailed NMR and mass spectrometry studies indicate that the ligand forms 1:2 complexes with lanthanide(III) perchlorates where the aliphatic rings are conformationally constrained whereas 1:1 complexes are formed with lanthanide(III) nitrates where the aliphatic rings are conformationally mobile. An optimized structure of the 1:2 solution complex with Yb(III) was obtained from the relative magnitude of the induced paramagnetic shifts. X-ray crystallographic structures of the ligand and of its 1:1 complex with Y(III) were also obtained. In the absence of a phase-modifier, CyMe 4 -BTTP in 1-octanol showed a maximum distribution coefficient of Am(III) of 0.039 (±20%) and a maximum separation factor of Am(III) over Eu(III) of 12.0 from nitric acid solution. The metal(III) cations are extracted as the 1:1 complex from nitric acid solutions. The generally low distribution coefficients observed compared with the BTBPs arise because the 1:1 complex of CyMe 4 -BTTP is considerably less hydrophobic than the 1:2 complexes formed by the BTBPs. In M(BTTP) 3+ complexes, there is a competition between the nitrate ions and the ligand for the complexation of the metal. (authors)

  9. Armazenamento de sementes de feijão submetidas a tratamentos sanitários alternativos

    Directory of Open Access Journals (Sweden)

    Cristina Fernanda Schneider

    2015-06-01

    Full Text Available O objetivo do trabalho foi comparar tratamentos alternativos em sementes de feijão visando à conservação da qualidade fisiológica e sanitária em diferentes ambientes de armazenagem. Sementes de feijão cultivar Mulatinho provenientes de cultivo orgânico de Marechal Cândido Rondon-PR, safra 2010/2011, foram submetidas aos tratamentos: testemunha; termoterapia: 60 °C em estufa de circulação forçada por três horas; folhas de Eucalyptus grandis: foram cortadas em pedaços pequenos e misturadas às sementes; e alho+óleo+cinzas: 100 gramas de alho e 500 mL de óleo Glycine max para cada 60 kg de sementes, sendo estes amassados e misturados às sementes, e, ao final, misturadas às cinzas. Após os tratamentos, as sementes foram armazenadas por 120 dias em embalagem impermeável e em condições ambientais controladas (10 ± 3 °C e 36 ± 3% de umidade e não controladas (mantidas em temperatura ambiente. Após o armazenamento foram determinados: grau de umidade, massa de mil sementes, 1ª contagem do teste de germinação, germinação final, índice de velocidade de germinação e sanidade. O tratamento testemunha armazenada em ambiente controlado proporcionou os melhores resultados, conservando a qualidade fisiológica e sanitária das sementes. 

  10. &apos;Heat Market Campaign&apos; of the German coal mining industry

    Energy Technology Data Exchange (ETDEWEB)

    Dach, G.

    1983-12-22

    The &apos;&apos;Heat Market Campaign&apos;&apos;, presented in June &apos;83 by experts of all fields of coal mining, investigates the possibilities of coal sales promotion. The article reviews the main data of the heat market and discusses the &apos;&apos;Heat Market Campaign&apos;&apos; under the aspects of coal policy and energy policy. The campaign was started with the objectives of energy supply assurance in the Federal Republic of Germany, energy cost reduction on the consumer side, and stabilisation and development of coal markets not affected by the steel crisis. Sales goald on the household, trade and industrial sector are quantified, and obstacles preventing further expansion of the heat market are discussed. Apart from the mining industry&apos;s marketing concept for the heat market, there is also the possibility of receiving financial aid by the Federal government.

  11. Network protocol &apos;EPAP&apos;; Network protokoru &apos;EPAP&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Kobori, T.; Fujita, F.; Iwamoto, S. [Fuji Electric Co. Ltd., Toyo (Japan)

    2000-10-10

    The Ethernet, a standard of information networks, has begun to be applied to the control local area network (LAN). To apply the Ethernet to the field level, Fuji Electric has newly developed the communication protocol &apos;Ethernet precision access protocol (EPAP)&apos; in which a command/response method is structured on the user datagram protocol (UDP) to realize real time and high reliability. Further, we have implemented the EPAP on the bus interface module of the open PIO. This paper outlines the EPAP and its implementation. (author)

  12. Blunt traumatic rupture of a mainstem bronchus: spiral CT demonstration of the &apos;&apos;fallen lung&apos;&apos; sign

    Energy Technology Data Exchange (ETDEWEB)

    Wintermark, M.; Schnyder, P.; Wicky, S. [Dept. of Diagnostic and Interventional Radiology, University Hospital, Lausanne (Switzerland)

    2001-03-01

    Tracheo-bronchial injuries occur in less than 1 % of blunt chest trauma patients. Indirect signs, such as pneumomediastinum, pneumothorax, and/or subcutaneous emphysema, are revealed on admission plain films and chest CT survey. In most instances, however, tracheo-bronchoscopy is mandatory in assessing the definite diagnosis of tracheo-bronchial lesion. Occasionally, an abnormal course of a mainstem bronchus or a &apos;&apos;fallen lung&apos;&apos; sign, featuring a collapsed lung in a dependent position, hanging on the hilum only by its vascular attachments, may allow for CT diagnosis of a blunt traumatic bronchial injury. (orig.)

  13. Prospects and risks for young technology companies. Chancen und Risiken junger Technologieunternehmen; Ergebnisse des Modellversuchs &apos;&apos;Foerderung technologieorientierter Unternehmensgruendungen&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Kulicke, M. (Fraunhofer-Institut fuer Systemtechnik und Innovationsforschung (ISI), Karlsruhe (Germany)); Bayer, K.; Braeunling, G.; Ewers, H.J.; Gerybadze, A.; Mayer, M.; Mueller, R.; Wein, T.; Wupperfeld, U.

    1993-01-01

    The book summarizes the insights gained from the model project &apos;&apos;Promotion of the establishment of technology-oriented companies&apos;&apos;. The manifold results on capital and consulting requirements, turnover and activity growth, factors determining success and survival and on the problems that arise during the starting phase broaden the informational basis for potential founders, their financers, and for promotion institutions. (orig.). 29 figs.

  14. Grape extract and α-Tocopherol effect in cardiovascular disease model of Apo E -/- Mice Efeito do extrato de uva e α-Tocoferol em camundongos Apo E -/-, modelo de doença cardiovascular

    Directory of Open Access Journals (Sweden)

    Maria do Carmo Gouveia Peluzio

    2011-08-01

    Full Text Available PURPOSE: To verify the effect of consumption of grape extract isolated or combined with α-tocopherol supplementation on atherosclerosis model with Apo E -/- mice. METHODS: After six weeks of atherogenic diet, Apo E -/- mice were divided into the following groups: Control, Grape, Tocopherol and Grape plus Tocopherol. The treatment progressed for 11 weeks when animals were submitted to euthanasia. RESULTS: All the treatments presented hypocholesterolemic effect with reduction of serum and liver cholesterol levels. This effect was parallel to an increase in the fecal excretion of cholesterol. There was also a higher fecal excretion of saturated fatty acids in groups receiving grape extract or α-tocopherol. All the groups treated presented a tendency to show higher levels of vitamin E. The fatty acid profile showed a tendency for monounsaturated fatty acid preservation after grape extract and α-tocopherol consumption. Morphological analysis revealed a lower degree of evolution of the atherosclerotic plaque of the animals that were fed α-tocopherol combined with grape extract, even when no difference was found in the size of the largest lesion. CONCLUSION: A synergistic effect between the polyphenols and α-tocopherol was observed, resulting in diminished evolution of atherosclerosis and a greater beneficial effect on atherosclerosis than the isolated consumption of antioxidants.OBJETIVO: Verificar o efeito do consumo de extrato de uva isolada ou combinada com a suplementação de α-tocoferol em modelo de aterosclerose, utilizando camundongos Apo E -/-. MÉTODOS: Os camundongos Apo E -/- foram tratados com dieta aterogênica por seis semanas e foram divididos em quatro grupos: Controle, Uva, Tocoferol e Uva e Tocoferol. Após 11 semanas de tratamento os animais foram submetidos à eutanasia. RESULTADOS: Todos os tratamentos apresentaram efeito hipocolesterolêmico, com redução de colesterol plasmático e hepático. Este efeito foi acompanhado

  15. Human ApoE Isoforms Differentially Modulate Glucose and Amyloid Metabolic Pathways in Female Brain: Evidence of the Mechanism of Neuroprotection by ApoE2 and Implications for Alzheimer's Disease Prevention and Early Intervention.

    Science.gov (United States)

    Keeney, Jeriel Thomas-Richard; Ibrahimi, Shaher; Zhao, Liqin

    2015-01-01

    Three major genetic isoforms of apolipoprotein E (ApoE), ApoE2, ApoE3, and ApoE4, exist in humans and lead to differences in susceptibility to Alzheimer's disease (AD). This study investigated the impact of human ApoE isoforms on brain metabolic pathways involved in glucose utilization and amyloid-β (Aβ) degradation, two major areas that are significantly perturbed in preclinical AD. Hippocampal RNA samples from middle-aged female mice with targeted human ApoE2, ApoE3, and ApoE4 gene replacement were comparatively analyzed with a qRT-PCR custom array for the expression of 85 genes involved in insulin/insulin-like growth factor (Igf) signaling. Consistent with its protective role against AD, ApoE2 brain exhibited the most metabolically robust profile among the three ApoE genotypes. When compared to ApoE2 brain, both ApoE3 and ApoE4 brains exhibited markedly reduced levels of Igf1, insulin receptor substrates (Irs), and facilitated glucose transporter 4 (Glut4), indicating reduced glucose uptake. Additionally, ApoE4 brain exhibited significantly decreased Pparg and insulin-degrading enzyme (Ide), indicating further compromised glucose metabolism and Aβ dysregulation associated with ApoE4. Protein analysis showed significantly decreased Igf1, Irs, and Glut4 in ApoE3 brain, and Igf1, Irs, Glut4, Pparg, and Ide in ApoE4 brain compared to ApoE2 brain. These data provide the first documented evidence that human ApoE isoforms differentially affect brain insulin/Igf signaling and downstream glucose and amyloid metabolic pathways, illustrating a potential mechanism for their differential risk in AD. A therapeutic strategy that enhances brain insulin/Igf1 signaling activity to a more robust ApoE2-like phenotype favoring both energy production and amyloid homeostasis holds promise for AD prevention and early intervention.

  16. Tratamento atual da insuficiência cardíaca descompensada Current insights into the modern treatment of decompensated heart failure

    Directory of Open Access Journals (Sweden)

    Fábio Vilas-Boas

    2006-09-01

    Full Text Available O tratamento de ICD representa um desafio até mesmo para o médico experiente. Os avanços alcançados nas pesquisas propiciaram novas opções de tratamento que estão ajudando a mudar paradigmas. As evidências indicam que novos fármacos como a levosimendana e nesiritida representarão importantes alternativas ou complementos ao tratamento com medicamentos inotrópicos tradicionais, como a dobutamina. O médico responsável pelo tratamento desses pacientes deve aprender a usar as melhores evidências disponíveis para individualizar o tratamento com segurança e eficácia.Treatment of DHF is a challenge even for the experienced physician. Advances in research have brought new treatment options that are helping change paradigms. The available evidence suggests that new drugs like levosimendan and nesiritide will assume relevant positions as alternatives or complements to treatment with traditional inotropic drugs like dobutamine. The physician responsible for treating these patients should learn how to use the best available evidence, in order to tailor treatment with safety and efficacy.

  17. Pharmaceutical induction of ApoE secretion by multipotent mesenchymal stromal cells (MSCs

    Directory of Open Access Journals (Sweden)

    Whitney Mandolin J

    2008-09-01

    Full Text Available Abstract Background Apolipoprotein E (ApoE is a molecular scavenger in the blood and brain. Aberrant function of the molecule causes formation of protein and lipid deposits or "plaques" that characterize Alzheimer's disease (AD and atherosclerosis. There are three human isoforms of ApoE designated ε2, ε3, and ε4. Each isoform differentially affects the structure and function of the protein and thus the development of disease. Homozygosity for ApoE ε4 is associated with atherosclerosis and Alzheimer's disease whereas ApoE ε2 and ε3 tend to be protective. Furthermore, the ε2 form may cause forms of hyperlipoproteinemia. Therefore, introduction of ApoE ε3 may be beneficial to patients that are susceptible to or suffering from these diseases. Mesenchymal stem cells or multipotent mesenchymal stromal cells (MSCs are adult progenitor cells found in numerous tissues. They are easily expanded in culture and engraft into host tissues when administered appropriately. Furthermore, MSCs are immunosuppressive and have been reported to engraft as allogeneic transplants. In our previous study, mouse MSCs (mMSCs were implanted into the brains of ApoE null mice, resulting in production of small amounts of ApoE in the brain and attenuation of cognitive deficits. Therefore human MSCs (hMSCs are a promising vector for the administration of ApoE ε3 in humans. Results Unlike mMSCs, hMSCs were found not to express ApoE in culture; therefore a molecular screen was performed for compounds that induce expression. PPARγ agonists, neural stem cell conditioned medium, osteo-inductive media, dexamethasone, and adipo-inductive media (AIM were tested. Of the conditions tested, only AIM or dexamethasone induced sustained secretion of ApoE in MSCs and the duration of secretion was only limited by the length of time MSCs could be sustained in culture. Upon withdrawal of the inductive stimuli, the ApoE secretion persisted for a further 14 days. Conclusion The data

  18. 7th CNS int&apos;l steam generators to controls conference - a compliment to the remarkable CNS &apos;OM+DM utility engagement initiative&apos;

    International Nuclear Information System (INIS)

    Schneider, W.

    2012-01-01

    We learned from CANDU Maintenance-Conference of December 2011, that it is our own &apos;ways-of-working&apos; as service-providers for everything from plant-architecture to operational-support, that is holding back &apos;new-build&apos; as well as &apos;re-build&apos;. CMC2011 addressed that by focusing on &apos;Needs-and-Interests of the Operating-Utilities&apos;. SGC 2012 extends that by focusing firstly on &apos;Issue-Identification&apos; to isolate &apos;items-needing-attention&apos;; then on &apos;Issue-Definition&apos; to define the &apos;work&apos; required for &apos;Issue-Resolution&apos;. It also pursues &apos;Task Leadership&apos; as a competence, essential for ... &apos;making things happen&apos;. These events and the CNS &apos;OM+DM [Operations&Maintenance and Design&Materials Divisions] Utility Engagement Initiative&apos; are seen as complimentary initiatives toward such &apos;ways-of-working-improvement&apos; objectives. (author)

  19. A model-independent &apos;&apos;general search&apos;&apos; for new physics with the ATLAS detector at LHC

    Energy Technology Data Exchange (ETDEWEB)

    Bianchi, Riccardo Maria

    2014-03-18

    The LHC particle collider accelerates bunches of protons at energies never reached before, thus opening a completely new landscape of new physics. In this scenario the number of possible physics processes and signatures becomes virtually infinite, making the setup of dedicated analyses impossible. Moreover there are regions of the phase-space where signals of new physics are not very likely to be found, or where suitable theoretical models are missing, and it is important to be able to reveal new processes from such regions as well. At the time this Thesis was started, no model-independent analysis had been set for the ATLAS experiment at LHC. The goal of this work was then to conceive and develop a new model-independent &apos;&apos;General Search&apos;&apos; for ATLAS, and to explore its possibilities. The new analysis has been then implemented and run over the first data which have been collected by the ATLAS experiment at a centre-of-mass energy of 7 TeV. This work presents the motivation of the data analysis, describes its implementation and shows the results. The data have shown a very good agreement with the Standard Model expectation and no evidence of new physics has been observed. Nevertheless, an efficient strategy and methodology for a new model-independent &apos;&apos;General Search&apos;&apos; have been defined and they are ready to be used in a next version of this analysis, over a larger set of experimental data. During this work, a new innovative software framework has been also conceived and developed to ease the implementation of physics analysis code using Computer-Aided- Software-Engineering (CASE) principles. The framework has been successfully used to analyze the very first LHC data, and then it has been transformed into an open-source modular framework for HEP data analysis, and presented at Physics and Computer Science international conferences.

  20. Efeito de diferentes tratamentos químicos em cama para aves de corte

    Directory of Open Access Journals (Sweden)

    Walter Lucca

    2012-04-01

    Full Text Available O objetivo do experimento foi avaliar diferentes tratamentos químicos em cama aviária para frango de corte. Foram 2 utilizadas 500 aves, em delineamento inteiramente casualizado, com cinco tratamentos: Hidróxido de cálcio (500g/m ; Sulfato de Alumínio (500g/m ; Sulfato de cálcio (1000g/m ; Sulfato de cálcio 48% + Filosilicato Expandido 28% (500g/m e testemunha com quatro repetições. As amostras de cama aviária foram coletadas a cada sete dias para determinação do pH, umidade e contagem bacteriana nos meios de cultura Ágar MacConkey, Plate Count Agar (PCA. O peso das aves não se diferenciaram estatisticamente aos 42 dias, porém se observou significância na mortalidade e a conversão alimentar, entretanto em relação ao pH da cama o ideal seria após o término da segunda semana fazer nova aplicação dos produtos químicos. Todos os tratamentos foram eficazes quanto à umidade. Na contagem bacteriana com o meio PCA para mesófilas totais houve redução do desenvolvimento bacteriano, porém com o meio Ágar MacConkey para Enterobactérias totais somente o tratamento a base de Sulfato de cálcio (48% + Filosilicato expandido (28% se mostrou significativo (P < 0,05. Para a análise estatística utilizou-se sistema SISVAR (Sistema de Analise Estatístico e Planejamento de Sistemas, 2006.

  1. Aluminum &apos;'egg-box'&apos; panel as an energy absorber for pedestrian protection

    Energy Technology Data Exchange (ETDEWEB)

    Nowpada, Sravanthi; Chirwa, Efford C.; Myler, Peter; Matsika, Emmanuel [Bolton Automotive and Aerospace Research Group (BAARG), School of Built Environment and Engineering, University of Bolton (United Kingdom)

    2010-07-15

    This paper evaluates the quasi-static performance of lightweight aluminum &apos;'egg-box'&apos; panels which have an improved architecture specifically designed to increase the energy absorption capability. In its entirety, the egg-box panel structure investigated herein is made up of arrays of positive and negative frusta. To understand the collapse mechanism and the factors influencing the energy absorption thereof, compressive tests were conducted under similar test conditions on two single frusta, one constrained in situ and the other separated from the egg-box panel exposing the free-free edges. Their load-displacement histories show characteristics that are similar, with a rise in load to a point where they plateau at a steady state load for the entire collapse time. But the energy absorbed by the in situ constrained frustum is 80% greater than that separated from the egg-box panel with free-free edges. (Abstract Copyright [2010], Wiley Periodicals, Inc.)

  2. Tratamento cirúrgico do divertículo de zenker

    Directory of Open Access Journals (Sweden)

    Nelson Adami Andreollo

    Full Text Available O divertículo de Zenker (DZ é uma doença muito pouco freqüente, cujo sintoma mais importante é a disfagia cervical. Os aspectos de sua etiopatogenia ainda são motivos de várias pesquisas na literatura, através de estudos manométricos e cinerradiográficos. O tratamento mais empregado é o cirúrgico, favorecendo quase a totalidade dos doentes, com índices de recidiva muito baixos. Porém, algumas publicações enfatizam as vantagens do tratamento endoscópico. Foram revisados 39 doentes, tratados no Serviço nos últimos 15 anos, sendo que 28 foram do sexo masculino (71,8%. A idade do grupo variou de 18 a 86 anos (média 54,5 anos. Os principais sintomas foram a disfagia cervical (89,8%, a regurgitação alimentar (71,8%, a tosse repetitiva (30.7% e o emagrecimento importante (25,6%. Dois pacientes apresentaram diverticulite aguda e perfuração (5,1 %. O diagnóstico foi estabelecido através de radiografias contrastadas em 37 pacientes (94,8% e de endoscopia digestiva em 28 (71,7%. A eletromanometria foi realizada em 13 casos (33,3%. O tratamento consistiu de diverticulectomia seguida de miotomia do esfincter do músculo cricofaríngeo em 24 pacientes (61,5% e diverticulopexia seguida da mesma miotomia em 15 pacientes (38,5%. No seguimento a longo prazo de 35 pacientes (89,8%, variando de cinco meses a 12 anos (média 4,5 anos, ocorreu melhora importante com desaparecimento da disfagia em todos os casos. Três pacientes (7,7% persistiram sintomas disfágicos leves e inconstantes. Um paciente faleceu em decorrência de complicações cardíacas e pulmonares. Os estudos histopatológicos dos divertículos ressecados mostraram a presença de tumor maligno neuroendócrino em um paciente (2,5%. Os doentes submetidos a diverticulopexia receberam alta hospitalar mais precocemente. Os autores discutem os aspectos atuais da fisiopatologia do DZ, analisam as opções de tratamento e os resultados da literatura, comparando com os obtidos neste

  3. Solar tank. &apos;Solar ship&apos; and solar development project at Freiburg; Sonne im Tank. &apos;Sonnenschiff&apos; und Solarsiedlung in Freiburg

    Energy Technology Data Exchange (ETDEWEB)

    Alle, N.

    2007-05-15

    In the &apos;Vauban&apos; district of the German city of Freiburg, 59 plusenergy terrace houses and one block of offices and shops were constructed during the past five years. The latter is named &apos;solar ship&apos; and has nine penthouses on its roof which generate more power than they consume. The building is 125 m long and is both a building and a power station. (orig.)

  4. Advice relative to the examination of the &apos;clay 2005 file&apos;; Avis relatif a l&apos;examen du &apos;dossier 2005 argile&apos;

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2005-12-15

    On request of the general director of the French nuclear safety and radiation protection institute (IRSN), the permanent group of experts for long duration waste disposal facilities has examined the &apos;clay 2005 file&apos; made by the ANDRA and which aims at demonstrating the feasibility of a disposal facility for high level and long living rad-wastes in the argillite formation of the Bure site. The group of experts has examined in particular the critical safety aspects of such a facility and the identification and consideration of uncertainties by the ANDRA in its safety analysis. It has also identified the main additional research works that may be carried out to demonstrate the feasibility of an industrial implementation of a safe disposal facility in the same Callovo-Oxfordian argilite formation. This document is the favourable advice and the recommendations expressed by the group of experts after examination of the ANDRA&apos;s &apos;clay 2005 file&apos;. (J.S.)

  5. Uso do fluralaner no tratamento da demodicidose canina juvenil generalizada: relato de caso

    Directory of Open Access Journals (Sweden)

    J.A.B. Bezerra

    Full Text Available RESUMO O objetivo do presente trabalho foi relatar a eficácia do fluralaner no tratamento da demodicidose juvenil generalizada canina. Dois caninos, apresentando dois e três meses de idade, com diagnóstico clínico e parasitológico de demodicidose generalizada, foram tratados com administração única de fluralaner, na dose recomendada em bula pelo fabricante. Além disso, foi realizada a terapia adjuvante à base de xampu de peróxido de benzoíla e domperidona. Observou-se uma resposta terapêutica satisfatória, com repilação completa ao 30º dia após a administração do fármaco. Para cada paciente, foi realizado exame parasitológico do raspado cutâneo aos 75 e 90 dias seguintes ao início do tratamento, e todos foram negativos. Tendo em vista a elevada eficácia do tratamento proposto, sugere-se a inclusão do fluralaner nos protocolos terapêuticos destinados à demodicidose canina, particularmente nos pacientes pediátricos e com a forma generalizada da doença.

  6. Cuts in energy and operating cost with the Swiss system &apos;Energie in ARA&apos; - practical experience in Germany; Energie- und Betriebskosteneinsparungen nach dem schweizerischen System &apos;&apos;Energie in ARA&apos;&apos; - Praxiserfahrungen in Deutschland

    Energy Technology Data Exchange (ETDEWEB)

    Christmann, B. [UmBAUwelt Partnerschaft Architekten und Ingenieure, Riedstadt (Germany)

    1999-07-01

    German sewage treatment plants, too, have potential for saving energy cost and cutting down on their operating expenditure. Following the systematy developed by the &apos;Energie in ARA&apos; concept, this potential can be harnessed. (orig.) [German] Potential fuer Energiekosteneinsparungen und dadurch initiierte Betriebskosteneinsparungen ist auch bei deutschen Klaeranlagen vorhanden. Die Systematik &apos;Energie in ARA&apos; kann fuer die Erschliessung der Einsparpotentiale verwendet werden. (orig.)

  7. &apos;&apos;1/f noise&apos;&apos; in music: Music from 1/f noise

    Energy Technology Data Exchange (ETDEWEB)

    Voss, R.F.; Clarke, J.

    1978-01-01

    The spectral density of fluctuations in the audio power of many musical selections and of English speech varies approximately as 1/f (f is the frequency) down to a frequency of 5 x 10/sup -4/ Hz. This result implies that the audio-power fluctuations are correlated over all times in the same manner as &apos;&apos;1/f noise&apos;&apos; in electronic components. The frequency fluctuations of music also have a 1/f spectral density at frequencies down to the inverse of the length of the piece of music. The frequency fluctuations of English speech have a quite different behavior, with a single characteristic time of about 0.1 s, the average length of a syllable. The observations on music suggest that 1/f noise is a good choice for stochastic composition. Compositions in which the frequency and duration of each note were determined by 1/f noise sources sounded pleasing. Those generated by white-noise sources sounded too random, while those generated by 1/f/sup 2/ noise sounded too correlated.

  8. Influência do tratamento enzimatico sobre as características reológicas e microscópicas da polpa de acerola

    Directory of Open Access Journals (Sweden)

    Luciana Balischi

    2002-04-01

    Full Text Available O consumo de sucos e bebidas à base de frutas tem aumentado consideravelmente nos últimos anos. No Brasil, destaca-se a produção da acerola (alto teor de vitamina C e de seus derivados. Objetivando melhoramentos na fabricação de sucos e derivados de frutas tropicais, surgiram pesquisas visando a encontrar o melhor tratamento enzimático. Neste trabalho, estudou-se a variação que ocorre na reologia da polpa integral de acerola submetida ao tratamento enzimático, bem como a variação no diâmetro médio das partículas, para as melhores condições de tratamento obtidas. Duas enzimas comerciais foram testadas: Citrozym Ultra L e Pectinex Ultra SP-L, variou-se as temperaturas, as concentrações das enzimas e os tempos de tratamento As características reológicas e microscópicas da polpa sofreram alterações com o tratamento enzimático.

  9. Nuclear track radiography of &apos;hot&apos; aerosol particles

    Energy Technology Data Exchange (ETDEWEB)

    Boulyga, S.F.; Kievitskaja, A.I.; Kievets, M.K.; Lomonosova, E.M.; Zhuk, I.V.; Yaroshevich, O.I.; Perelygin, V.P.; Petrova, R.; Brandt, R.; Vater, P

    1999-06-01

    Nuclear track radiography was applied to identify aerosol &apos;hot&apos; particles which contain elements of nuclear fuel and fallout after Chernobyl NPP accident. For the determination of the content of transuranium elements in radioactive aerosols the measurement of the {alpha}-activity of &apos;hot&apos; particles by SSNTD was used in this work, as well as radiography of fission fragments formed as a result of the reactions (n,f) and ({gamma},f) in the irradiation of aerosol filters by thermal neutrons and high energy gamma quanta. The technique allowed the sizes and alpha-activity of &apos;hot&apos; particles to be determined without extracting them from the filter, as well as the determination of the uranium content and its enrichment by {sup 235}U, {sup 239}Pu and {sup 241}Pu isotopes. Sensitivity of determination of alpha activity by fission method is 5x10{sup -6} Bq per particle. The software for the system of image analysis was created. It ensured the identification of track clusters on an optical image of the SSNTD surface obtained through a video camera and the determination of size and activity of &apos;hot&apos; particles00.

  10. Calogero&apos;s &apos;goldfish&apos; is indeed a school of free particles

    Energy Technology Data Exchange (ETDEWEB)

    Nucci, M C [Dipartimento di Matematica e Informatica, Universita di Perugia, 06123 Perugia (Italy)

    2004-11-26

    A many-body system of N nonlinear ordinary differential equations of second order which is amenable to exact treatments (a &apos;goldfish&apos;) (Calogero 2001 The neatest many-body problem amenable to exact treatments (a &apos;goldfish&apos;?) Physica D 152-153 78-84) is shown to be equivalent through an exact transformation to the equations of one-dimensional motion of (N-1) free particles (a school of free particles, indeed). The transformation is obtained by applying the reduction method and Lie group analysis as introduced in Nucci (1996 The complete Kepler group can be derived by Lie group analysis J. Math. Phys. 37 1772-5)

  11. Aharonov-Bohm effect for a fermion field in a planar black hole &apos;'spacetime'&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Anacleto, M.A.; Mohammadi, A. [Universidade Federal de Campina Grande, Departamento de Fisica, Caixa Postal 10071, Campina Grande, Paraiba (Brazil); Brito, F.A. [Universidade Federal de Campina Grande, Departamento de Fisica, Caixa Postal 10071, Campina Grande, Paraiba (Brazil); Universidade Federal da Paraiba, Departamento de Fisica, Caixa Postal 5008, Joao Pessoa, Paraiba (Brazil); Passos, E. [Universidade Federal de Campina Grande, Departamento de Fisica, Caixa Postal 10071, Campina Grande, Paraiba (Brazil); Universidade Federal do Rio de Janeiro, Instituto de Fisica, Caixa Postal 21945, Rio de Janeiro (Brazil)

    2017-04-15

    In this paper we consider the dynamics of a massive spinor field in the background of the acoustic black hole spacetime. Although this effective metric is acoustic and describes the propagation of sound waves, it can be considered as a toy model for the gravitational black hole. In this manner, we study the properties of the dynamics of the fermion field in this &apos;'gravitational'&apos; rotating black hole as well as the vortex background. We compute the differential cross section through the use of the partial wave approach and show that an effect similar to the gravitational Aharonov-Bohm effect occurs for the massive fermion field moving in this effective metric. We discuss the limiting cases and compare the results with the massless scalar field case. (orig.)

  12. The Effect of a High-Fat Diet on Brain Plasticity, Inflammation and Cognition in Female ApoE4-Knockin and ApoE-Knockout Mice.

    Directory of Open Access Journals (Sweden)

    Carola I F Janssen

    Full Text Available Apolipoprotein E4 (ApoE4, one of three common isoforms of ApoE, is a major risk factor for late-onset Alzheimer disease (AD. ApoE-deficient mice, as well as mice expressing human ApoE4, display impaired learning and memory functions and signs of neurodegeneration. Moreover, ApoE protects against high-fat (HF diet induced neurodegeneration by its role in the maintenance of the integrity of the blood-brain barrier. The influence of a HF diet on the progression of AD-like cognitive and neuropathological changes was assessed in wild-type (WT, human ApoE4 and ApoE-knockout (ApoE-/- mice to evaluate the modulatory role of ApoE in this process. From 12 months of age, female WT, ApoE4, and ApoE-/- mice were fed either a standard or a HF diet (19% butter, 0.5% cholate, 1.25% cholesterol throughout life. At 15 months of age mice performed the Morris water maze, evaluating spatial learning and memory. ApoE-/- showed increased spatial learning compared to WT mice (p = 0.009. HF diet improved spatial learning in WT mice (p = 0.045, but did not affect ApoE4 and ApoE-/- mice. Immunohistochemical analyses of the hippocampus demonstrated increased neuroinflammation (CD68 in the cornu ammonis 1 (CA1 region in ApoE4 (p = 0.001 and in ApoE-/- (p = 0.032 mice on standard diet. HF diet tended to increase CD68 in the CA1 in WT mice (p = 0.052, while it decreased in ApoE4 (p = 0.009, but ApoE-/- remained unaffected. A trend towards increased neurogenesis (DCX was found in both ApoE4 (p = 0.052 and ApoE-/- mice (p = 0.068. In conclusion, these data suggest that HF intake induces different effects in WT mice compared to ApoE4 and ApoE-/- with respect to markers for cognition and neurodegeneration. We propose that HF intake inhibits the compensatory mechanisms of neuroinflammation and neurogenesis in aged female ApoE4 and ApoE-/- mice.

  13. Quantifying the &apos;naturalness&apos; of the curvaton model

    Energy Technology Data Exchange (ETDEWEB)

    Lerner, Rose N. [Deutsches Elektronen-Synchrotron (DESY), Hamburg (Germany); Helsinki Institute of Physics (Finland); Melville, Scott [Helsinki Institute of Physics (Finland)

    2014-02-15

    We investigate the probability of obtaining an observable curvature perturbation, using as an example the minimal curvaton-Higgs (MCH) model. We determine &apos;probably observable&apos; and &apos;probably excluded&apos; regions of parameter space assuming generic initial conditions and applying a stochastic approach for the curvaton&apos;s evolution during inflation. Inflation is assumed to last longer than the N{sub obs}≅55 observable e-folds, and the total number of e-folds of inflation determines the particular ranges of parameters that are probable. For the MCH model, these &apos;probably observable&apos; regions always lie within the range 8 x 10{sup 4} GeV≤m{sub σ}≤2 x 10{sup 7} GeV, where m{sub σ} is the curvaton mass, and the Hubble scale at horizon exit is chosen as H{sub *}=10{sup 10} GeV. Because the &apos;probably observable&apos; region depends on the total duration of inflation, information on parameters in the Lagrangian from particle physics and from precision CMB observables can therefore provide information about the total duration of inflation, not just the last N{sub obs} e-folds. This method could also be applied to any model that contains additional scalar fields to determine the probability that these scalar fields contribute to the curvature perturbation.

  14. PubliForum &apos;Electricity and Society&apos;. Citizen Panel Report

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1998-06-01

    In the Citizen Panel&apos;s Report on &apos;Electricity and Society&apos; we present the first results of three intensive week-ends. In this document, 27 Swiss citizens have recorded their opinions on the future of our electricity supply system. Solutions are sought without making claims on having found the ultimate recipe. The recommendations are the result of an assessment made by a representative cross-section of the public - one could almost say &apos;the voice of the people&apos;. They reflect not only the public&apos;s apprehensions and worries, but also their ideas and desires. (authors)

  15. 3&apos;,8&apos;&apos;-biisokaempferide, a cytotoxic biflavonoid and other chemical constituents of Nanuza plicata (Velloziaceae)

    Energy Technology Data Exchange (ETDEWEB)

    Pinto, Meri Emili F.; Silva, Marcelo Sobral da; Barbosa Filho, Jose Maria; Castello-Branco, Marianna Vieira S.; Agra, Maria de Fatima; Tavares, Josean Fechine, E-mail: marcelosobral@ltf.ufpb.b [Universidade Federal da Paraiba (UFPB), Joao Pessoa, PB (Brazil). Lab. de Tecnologia Farmaceutica; Schindler, Elisabete; El-Bacha, Ramon dos Santos [Universidade Federal da Bahia (UFBA), Salvador, BA (Brazil). Inst. de Ciencias da Saude. Lab. de Neuroquimica e Biologia Celular

    2010-07-01

    A novel biflavonoid, named 3&apos;,8&apos;&apos;-biisokaempferide (1), along with the known compounds amentoflavone (2), patagonic acid (3), (4aR,5S,6R,8aR)-5-[2-(2,5-Dihydro-5-methoxy-2-oxofuran- 3-yl)ethyl]-3,4,4a,5,6,7,8,8a-octahydro-5,6,8a- trimethylnaphthalene-1-carboxylic acid (4), 5-caffeoylquinic acid methyl ester (5), 3,5-di-caffeoylquinic acid (6) and luteolin (7), were isolated of the leaves from Nanuza plicata. The compounds 3, 4, 5 and 6 are reported for the first time in Velloziaceae. The structures of the compounds were elucidated on the basis of spectroscopic methods, especially NMR and MS analyses. The cytotoxicity of 3&apos;,8&apos;&apos;-biisokaempferide was studied in cultures of human glioblastoma GL-15 cells. The effective concentration, which killed 50 % of cells after 72 h was 36.5 {mu}mol L{sup -1}. Changes in cellular morphology, including retraction and degradation of cytoplasm, were observed when cells were treated with concentrations from 20 {mu}mol L-1 of 3&apos;,8&apos;&apos;-biisokaempferide for 72 h. (author)

  16. Tratamento de esgoto sanitário em sistemas alagados construídos cultivados com lírio-amarelo

    OpenAIRE

    Prata,Renata C. C.; Matos,Antonio T. de; Cecon,Paulo R.; Monaco,Paola A. V. Lo; Pimenta,Leonardo A.

    2013-01-01

    Neste artigo, avaliou-se a eficiência de quatro sistemas alagados construídos (SACs) no tratamento de esgoto sanitário após ser submetido a tratamento preliminar e, no caso de alguns SACs, a tratamento primário (tanque séptico). Os SACs foram cultivados com lírio-amarelo (Hemerocallis flava), tendo a brita #0 como meio suporte, e submetidos às taxas de carregamento orgânico (TCO) de esgoto sanitário, em termos de DBO (kg ha-1 d-1), de 44; 98; 230 e 395 kg ha-1 d-1 e tempos de detenção hidrául...

  17. Representações sociais e adesão ao tratamento antirretroviral (Social Representations and Adherence to Antiretroviral Treatment

    Directory of Open Access Journals (Sweden)

    Brigido Vizeu Camargo

    2014-12-01

    Full Text Available Resumo Este trabalho teve como objetivo identificar as representações sociais e os fatores que influenciam a adesão ao tratamento antirretroviral. Participaram do estudo 154 pessoas que faziam tratamento antirretroviral, sendo 82 homens com média de idade de 40 anos e 3 meses. Os dados foram obtidos por meio de entrevistas diretivas e por uma escala de adesão ao tratamento antirretroviral. O material textual sobre o significado do tratamento foi analisado pelo software IRAMUTEQ. O tratamento é representado a partir de duas concepções: a primeira a uma vida normal mantida pela ideia de uso contínuo e regular dos medicamentos, compartilhada pelas pessoas com alta adesão ao tratamento. Já a segunda, como algo que gera sofrimento e isolamento social, mais característica de pessoas com baixa/inadequada e insuficiente/ regular adesão. Sobre o nível de adesão, os resultados indicaram que 22.7% dos participantes apresentaram adesão alta/ estrita, e que a relação com o médico, a equipe de saúde e a informação sobre o tratamento estão relacionados com a alta/estrita adesão ao tratamento antirretroviral dos participantes. Abstract This study aims to identify the social representations and the factors that influence in the adherence to antiretroviral treatment. The participants in the study were 154 people who were undergoing antiretroviral treatment, 82 men with an average age of 40 years and three months. The data was obtained through direct interviews and through a scale of adherence to antiretroviral treatment. The textual material in relation to the meaning of the treatment was analyzed by the IRAMUTEQ software. The treatment is represented in two concepts: First, from a normal life maintained by the idea of continuous and regular use of medications shared by people with high adherence to treatment. Second, as something which generates social suffering, and isolation, most characteristic of people with low/inadequate, and

  18. PHS terminal &apos;TEGACKY&apos; dedicated to e-mailing; Mail senyo PHS tanmatsu &apos;TEGACKY

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2000-03-01

    The e-mail utilization rate at mobile communication terminals is increasing at a remarkable rate, as if to grow above the rate of communication by voice. Under the circumstances, a PHS (Personal Handyphone System) terminal &apos;TEGACKY&apos; (type name: PM-T101) has been developed, designed exclusively for use for e-mailing. &apos;TEGACKY&apos; is characterized in that its icons may be activated with pen, that input may be made by handwriting, and that its large screen allows a 48-character message consisting of 4 lines of 12 characters to be displayed at one time despite its compact size. It can also perform communication directly with other terminals or e-mail via center, and is provided with an information service function. &apos;TEGACKY&apos; having such distinguished features has created a new category of terminals which are at once e-mailing tools. (translated by NEDO)

  19. The &apos;Transnuklear affair&apos; and its consequences. Die &apos;Transnuklear-Affaere&apos; und ihre Auswirkungen

    Energy Technology Data Exchange (ETDEWEB)

    Brinkert, M.

    1992-03-01

    The &apos;Bribe&apos; and &apos;Drum&apos; Affairs and suspected proliferation in connection with Transnuklear GmbH public around the turn of 1987/88. Many members of the press wished them to speed up the process of opting out of nuclear power. However, none of the accusations specifically related to nuclear power leveled at that time turned out to be tenable. Instead, all violations of the law which had been detected could have been punished in the same way as in any other branch of industry. As a consequence, the impacts arising to regulatory structures in the nuclear sector, especially the measures taken by the Federal Government, may be considered to have been unjustified in scope. The TN Affair and the associated litigation has caused a great deal of confidence in nuclear power to be lost, which now has to be reclaimed by purposeful public relations efforts. (orig.).

  20. Diretrizes brasileiras para o tratamento da narcolepsia Brazilian guidelines for the treatment of narcolepsy

    Directory of Open Access Journals (Sweden)

    Flávio Alóe

    2010-09-01

    Full Text Available Este artigo relata as conclusões da reunião de consenso da Associação Brasileira de Sono com médicos especialistas brasileiros sobre o tratamento da narcolepsia, baseado na revisão dos artigos sobre narcolepsia publicados entre 1980 e 2010. Os objetivos do consenso são valorizar o uso de agentes avaliados em estudos randomizados placebo-controlados, emitir recomendações de consenso para o uso de outras medicações e informar pontos importantes a respeito da segurança e efeitos adversos das medicações. O tratamento da narcolepsia é baseado em diversas classes de agentes, estimulantes para sonolência excessiva, agentes antidepressivos para cataplexia e hipnóticos para sono noturno fragmentado. Medidas comportamentais são igualmente importantes e recomendadas universalmente. Todos os ensaios clínicos terapêuticos foram classificados de acordo com o nível de qualidade da evidência. Recomendações terapêuticas individualizadas para cada tipo de sintoma e recomendações gerais foram formuladas pelos autores. Modafinila é indicada como a primeira escolha para o tratamento da sonolência diurna. Agentes de segunda escolha para o tratamento da sonolência excessiva são metilfenidato de liberação lenta seguido pelo mazindol. Reboxetina, clomipramina, venlafaxina, desvenlafaxina e os inibidores seletivos de recaptação de serotonina em doses altas são a primeira escolha para o tratamento da cataplexia. Hipnóticos são utilizados para o tratamento do sono noturno fragmentado. Antidepressivos e hipnóticos são igualmente utilizados para o tratamento das alucinações hipnagógicas e paralisia do sono.This manuscript contains the conclusion of the consensus meeting of the Brazilian Sleep Association with Brazilian sleep specialists on the treatment of narcolepsy based on the review of medical literature from 1980 to 2010. The manuscript objectives were to reinforce the use of agents evaluated in randomized placebo

  1. Solar campaign &apos;Solar - na klar.&apos; (solar - of course). Final report; Solarkampagne &apos;Solar - na klar.&apos;. Abschlussbericht

    Energy Technology Data Exchange (ETDEWEB)

    Gege, M.; Kleinsteuber, A.; Krabbe, P.; Kroeger, P.; Maschke, K.; Niedert, S.; Schindelmann, F.; Thunert, A.; Weinberg, H.

    2002-03-18

    The German market for technically matured solar-thermal systems for generating hot water is growing by 20 per cent per year, with some deviations due to incentive policies. This growth can be and is planned to be increased systematically, with following goals: A practical contribution to the Federal Government&apos;s efforts to achieve the goals regarding the protection of climate; creating future-oriented jobs; supporting ecologically sustainable ways of life and models of consumption by convincing the consumers and other target groups of the fact that it makes sense already today to start utilizing solar energy and to invest also on private basis. These targets are expected to be set up with the help of a three-year mass campaign (1999 until 2001), i.e. the campaign called &apos;&apos;Solar - na klar.&apos;&apos; (solar - of course). [German] Der deutsche Markt fuer die technisch ausgereiften solarthermischen Anlagen zur Warmwassererzeugung waechst mit ca. 20% p.a., mit foerderpolitisch bedingten Schwankungen. Dieses Wachstum kann und soll systematisch gesteigert werden, mit folgenden Zielsetzungen: Praktischer Beitrag zur Erreichung der Klimaschutzziele der Bundesregierung; Schaffung zukunftsorientierter Arbeitsplaetze; Befoerderung oekologisch nachhaltiger Lebensstile und Konsummuster durch die Ueberzeugung der Verbraucher und weiterer Zielgruppen, dass es heute bereits sinnvoll ist, in die Nutzung der Solarenergie konkret einzusteigen und auch privat zu investieren. Diese Ziele sollen mithilfe einer auf drei Jahre angelegten Breitenkampagne (1999 bis 2001), d.h. der Kampagne &apos;Solar - na klar.&apos; erfolgen. (orig.)

  2. The energy and monetary implications of the &apos;24/7 &apos;always on&apos; society

    Energy Technology Data Exchange (ETDEWEB)

    Loveday, Dennis L. [Department of Civil and Building Engineering, Loughborough University, Loughborough, Leicestershire LE11 3TU (United Kingdom); Bhamra, T.; Tang, T. [Department of Design and Technology, Loughborough University, Loughborough, Leicestershire LE11 3TU (United Kingdom); Haines, V.J.A. [Ergonomics and Safety Research Institute (ESRI), Loughborough University, Loughborough, Leicestershire LE11 3TU (United Kingdom); Holmes, M.J. [ARUP, 13, Fitzroy Street, London W1T 4BR (United Kingdom); Green, R.J. [Institute for Energy Research and Policy, University of Birmingham, Edgbaston, Birmingham B15 2TT (United Kingdom)

    2008-12-15

    This paper reviews the trends in society, technology and energy demand of the past 30 years, together with the growth of the &apos;on-demand&apos; culture. The &apos;24/7&apos; or &apos;always on&apos; society can be defined as one where people demand - and generally receive - what they want &apos;now&apos;. It has grown up in parallel with developments in information technology, which have produced the services needed to meet that demand. Larger numbers of appliances, resulting from greater affluence and disposable income, have increased energy use, despite energy efficiencies in other areas. While monetary factors suggest that changes brought about by the 24/7 society will generally be self-correcting at the macro-economic level, there will nevertheless be effects for individuals, such as potentially severe impacts on the fuel poor as electricity prices rise. We conclude with a view of future directions. As the 24/7 culture continues to grow, there is scope for designers and for information technology to manage and reduce energy consumption. This includes buildings, their services systems, and the mix of new technologies that will be deployed over the next 20 years or so, including the possibilities for data exchange and control at the interface between energy suppliers and consumers, coupled with greater understanding of the behaviour of the consumers themselves. (author)

  3. Revisão sistemática sobre tratamentos psicológicos para problemas relacionados ao crack

    Directory of Open Access Journals (Sweden)

    Viviane Samoel Rodrigues

    2013-09-01

    Full Text Available OBJETIVO: O objetivo deste artigo é apresentar uma revisão sistemática da literatura sobre tratamentos psicológicos oferecidos para usuários de crack. MÉTODOS: Foi realizada uma revisão sistemática por meio de uma busca na literatura internacional e nacional, indexada nas bases de dados Medline, SciELO, Lilacs e Web of Science. Os descritores utilizados foram: crack or crack cocaine or cocaine smokers (crack and psychosocial treatment or psycotherapy or psychosocial treatment (tratamento psicológico e a busca incluiu artigos publicados no período de 2001 a 2011. RESULTADOS: No total foram encontrados 155 artigos por meio dos descritores utilizados. Os artigos foram agrupados em três dimensões: tratamentos psicossociais na internação e cuidados continuados, relaxamento respiratório e outras técnicas comportamentais e abordagens fundamentadas na Entrevista Motivacional, Cognitivo-Comportamental e Modelo Transteórico de Mudança. CONCLUSÃO: Com base nos estudos examinados, pode ser formulado um elenco de algumas intervenções que estão sendo estudadas para o tratamento de usuários de crack e algumas apresentam resultados satisfatórios. Os poucos esforços de comparação entre técnicas resultaram em evidências de pouca ou nenhuma diferença, ainda que se registre o benefício para os usuários na aplicação de qualquer delas. Não existe consenso acerca da efetividade no tratamento de usuários de crack. Parece oportuno e necessário o aprofundamento dos estudos nesse campo.

  4. Measure of the e+e-{yields}bb Cross Section at the LEP Energies; Medida de la seccion eficaz e&apos;'+e'&apos;-{yields}bb a las Energias de LEP

    Energy Technology Data Exchange (ETDEWEB)

    Arce Dubois, P.

    1992-07-01

    In the present work I analyse the data collected during 1990 by the L3 detector, situated in the electron-positron collider LEP. After selecting the events e&apos;'+e'&apos;-{yields} bb through their semileptonic decays into muons, I calculate the cross section for the process e&apos;'+e'&apos;- {yields} bb at different energy points around the mass of the vectorial boson Z, and I measure some parameters of the Standard Model, namely, the Br(b{yields}{mu} ),{gamma}{sub z}n-{yields}bb/{gamma}{sub z}n{yields}had and {gamma}{sub z}n{yields}bb{gamma}{sub z}n{yields}e&apos;'+e'&apos;-. (Author) 26 refs.

  5. História dos tratamentos biológicos Biologicals treatments's history

    Directory of Open Access Journals (Sweden)

    Sérgio Paulo Rigonatti

    2004-01-01

    Full Text Available Contexto: Trata-se de uma discussão de como surgiram os tratamentos biológicos no decorrer da história da psiquiatria.Context: It's about a discussion on how begun the biological treatment throughout Psychiatry History.

  6. A acetamida de pirrolidona como medicação auxiliar no tratamento da paralisia cerebral

    Directory of Open Access Journals (Sweden)

    Francisca Salete Pinheiro Chagas Ribeiro

    1976-06-01

    Full Text Available Vinte crianças, com diagnóstico de paralisia cerebral (PC e sob tratamento clássico, fisioterápico e pedagógico, receberam piracetam (acetamida de pirrolidona como medicação auxiliar. O objetivo foi melhorar os problemas de espasticidade, apredizagem, neurolabilidade, visando a um rendimento melhor do tratamento global da PC. O grupo medicado foi comparado com um grupo controle de 20 crianças que só eram objeto do tratamento habitual. A comparação mostrou resultados favoráveis no grupo medicado. A droga foi administrada na dose de 80 mg/kg/dia durante 10 semanas. Os critérios de avaliação dos resultados foram psicológicos, clínico, fisioterápico e pedagógico. A droga foi administrada em nova forma de apresentação: solução, para uso oral, a 6%.

  7. Changes in the &apos;medical research&apos; licensing procedure under the German Radiation Protection Ordinance; Neuerungen im Genehmigungsverfahren &apos;Medizinische Forschung&apos; gemaess Roentgen- und Strahlenschutzverordnung

    Energy Technology Data Exchange (ETDEWEB)

    Habeck, M.; Minkov, V.; Griebel, J.; Brix, G. [Bundesamt fuer Strahlenschutz (BfS), Oberschleissheim-Neuherberg (Germany). Fachbereich Strahlenschutz und Gesundheit; Epsch, R.; Langer, M. [Deutsche Roentgengesellschaft e.V. (DRG), Berlin (Germany). Klinische Studienkoordination

    2012-06-15

    This publication outlines the &apos;medical research&apos; licensing procedure as specified in the amendment of the German Radiation Protection Ordinance of November 1, 2011. The general licensing requirements for the use of radiation have not been changed by the amendment. Three so-called use restrictions (i.e., dose limits of 10 mSv and 20 mSv, age limit of 50 years) have been modified. They will only apply to healthy volunteers in the future. In addition, there are considerable simplifications with respect to applications and licensing procedures of the Federal Office for Radiation Protection (Bundesamt fuer Strahlenschutz, BfS) regarding the use of radiation in the newly introduced &apos;accompanying diagnostics&apos; (&apos;Begleitdiagnostik&apos;) case group. The newly established, independent panel of experts at the German Radiological Society (Deutsche Roentgengesellschaft, DRG) may provide essential support to principal investigators, qualified physicians and sponsors for differentiating between &apos;medical research&apos; and &apos;health care&apos;, the latter not being subject to licensing. An expert statement will be issued by the DRG within four weeks of an inquiry. This consulting service is subject to confidentiality, and is free of charge for inquirers and without any commitment. (orig.)

  8. Obesidade infantil: uma proposta de tratamento comportamental

    OpenAIRE

    Cruz, Maria Tereza Monteiro da

    2012-01-01

    O objetivo da presente pesquisa foi avaliar um programa de economia de fichas para modificar o comportamento de crianças obesas. Participaram do estudo dois jovens do sexo masculino com idades de 10 e 11 anos uma adolescente com 15 anos, todos apresentavam peso excessivo para a idade e freqüentavam uma ONG voltada para o tratamento da obesidade infantil e suas mães. A pesquisadora emprestou uma filmadora para os participantes e solicitou que P1 filmasse o almoço e o jantar cinc...

  9. Hybrid coolers allow important water saving; Les refroidisseurs &apos;'hybrides'&apos; permettent des economies d&apos;eau importantes

    Energy Technology Data Exchange (ETDEWEB)

    Bitsch, V. [Societe Jaeggi-France (France)

    2005-03-01

    Air cooling systems used with refrigerating machineries are in general highly water and electricity consuming. The use of &apos;hybrid&apos; systems having the characteristics of both close-cycle evaporative systems and dry coolers allow important water saving. This article presents the operation principle and characteristics of such cooling systems. (J.S.)

  10. Assessment report of research and development on &apos;the abolition measures of nuclear facilities and associated technology development&apos; and &apos;radioactive waste treatment and disposal and associated technology development&apos; (result evaluation, in advance evaluation) and &apos;technology development related to reprocessing of nuclear fuel material&apos; (In advance evaluation)

    International Nuclear Information System (INIS)

    2015-07-01

    Japan Atomic Energy Agency (hereinafter referred to as &apos;JAEA&apos;) consulted the &apos;Evaluation Committee for Decommissioning and Radioactive Waste Management &apos; for result evaluation and in advance evaluation of &apos;The abolition measures of nuclear facilities and associated technology development&apos; project and &apos;Radioactive waste treatment and disposal and associated technology development&apos; project and &apos;Technology development related to reprocessing of nuclear fuel material&apos; project in accordance with the &apos;Guideline for evaluation of government R and D activities&apos;, the &apos;Guideline for evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology (MEXT)&apos; and the &apos;Operational rule for evaluation of R and D activities&apos; by JAEA. In response to the JAEA&apos;s request, the Evaluation Committee for Decommissioning and Radioactive Waste Management, in accordance with the evaluation method as defined in the Committee deliberations and oral report and deliberation of material about the R and D project of three was conducted. This report summarizes the results of the assessment by the Committee with the Committee report. (author)

  11. Class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion.

    Science.gov (United States)

    Dresselhaus, Erica; Duerr, James M; Vincent, Fabien; Sylvain, Emily K; Beyna, Mercedes; Lanyon, Lorraine F; LaChapelle, Erik; Pettersson, Martin; Bales, Kelly R; Ramaswamy, Gayathri

    2018-01-01

    Despite the important role of apolipoprotein E (apoE) secretion from astrocytes in brain lipid metabolism and the strong association of apoE4, one of the human apoE isoforms, with sporadic and late onset forms of Alzheimer's disease (AD) little is known about the regulation of astrocytic apoE. Utilizing annotated chemical libraries and a phenotypic screening strategy that measured apoE secretion from a human astrocytoma cell line, inhibition of pan class I histone deacetylases (HDACs) was identified as a mechanism to increase apoE secretion. Knocking down select HDAC family members alone or in combination revealed that inhibition of the class I HDAC family was responsible for enhancing apoE secretion. Knocking down LXRα and LXRβ genes revealed that the increase in astrocytic apoE in response to HDAC inhibition occurred via an LXR-independent pathway. Collectively, these data suggest that pan class I HDAC inhibition is a novel pathway for regulating astrocytic apoE secretion.

  12. Eficiência de lagoas de polimento no pós-tratamento de reator UASB no tratamento de águas residuárias de suinocultura

    Directory of Open Access Journals (Sweden)

    A.C.A. Pinto

    2014-04-01

    Full Text Available Avaliou-se o desempenho de um sistema de lagoas seriadas que recebeu efluentes de reator UASB, no tratamento de águas residuárias de suinocultura. O sistema foi composto de reator anaeróbio de chicanas (RAC, reator UASB, em escala real, e uma série de lagoas (uma lagoa facultativa e três de maturação, em escala piloto. As análises físico-químicas realizadas foram: pH, demanda bioquímica de oxigênio (DBO, demanda química de oxigênio (DQO, sólidos suspensos totais (SST, sólidos suspensos voláteis (SSV, nitrogênio amoniacal (N-am., fósforo total (Pt, coliformes totais (CT e Escherichia coli (EC. As lagoas de pós-tratamento contribuíram eficientemente para remoção de nutrientes, matéria orgânica e sólidos, fornecendo um efluente com qualidade para o reuso agrícola ou lançamento em corpos d'água.

  13. Prospects for neutron star equation of state constraints using &apos;'recycled'&apos; millisecond pulsars

    Energy Technology Data Exchange (ETDEWEB)

    Bogdanov, Slavko [Columbia University, Columbia Astrophysics Laboratory, New York, NY (United States)

    2016-02-15

    &apos;'Recycled'&apos; millisecond pulsars are a variety of rapidly spinning neutron stars that typically show thermal X-ray radiation due to the heated surface of their magnetic polar caps. Detailed numerical modeling of the rotation-induced thermal X-ray pulsations observed from recycled millisecond pulsars, including all relevant relativistic and stellar atmospheric effects, has been identified as a promising approach towards an astrophysical determination of the true neutron star mass-radius relation, and by extension the state of cold matter at densities exceeding those of atomic nuclei. Herein, I review the basic model and methodology commonly used to extract information regarding neutron star structure from the pulsed X-ray radiation observed from millisecond pulsars. I also summarize the results of past X-ray observations of these objects and the prospects for precision neutron star mass-radius measurements with the upcoming Neutron Star Interior Composition Explorer (NICER) X-ray timing mission. (orig.)

  14. Energy and the new class. [Assault of &apos;&apos;new breed&apos;&apos; of American on established institutions

    Energy Technology Data Exchange (ETDEWEB)

    King, L.

    1979-03-14

    The bounty of the US is taken for granted by its population. Nowhere is this misvaluation of a society and its benefits more evident than in the energy industries. But energy represents a tool by which society can be shaped; a device by which the standared of living and the very nature of the national lifestyle can be controlled, modified, amplified, or reduced. Two examples examined to show how energy shapes social order and human life are the women&apos;s movement and the desire to live in the Sunbelt. Five phenomena are then examined to point out the desire to restrain the nation&apos;s rampant pursuit of a higher standard of living, as opposed to the more subjective and seemingly more desirable goal of a better quality of life: the civil rights movement; the environmental movement; the Vietnam War; the Watergate scandal; and the assumption that prosperity at today&apos;s level is irreducible, concrete, and not subject to diminution. The &apos;&apos;new class&apos;&apos; is essentially made up of those educated in the liberal arts, divorced from an understanding of the mechanics of free-enterprise institutions and of the sicences. The antagonistic view of the new class of corporations and its assault on established institutions are noted. Energy companies are frustrated in telling their story, but the story that must be told is not the story of how excellently the energy sector has performed, but the story of how a new breed of Americans is seeking to remake America in its own image without the rest being aware of what is going on. (MCW)

  15. Fisioterapia no tratamento da dor orofacial de pacientes com disfunção temporomandibular crônica

    Directory of Open Access Journals (Sweden)

    Ana Lúcia Franco

    2011-03-01

    Full Text Available Estudos recentes têm demonstrado resultados consistentes com o uso das terapias físicas nos casos de dor e limitação de movimentos em Disfunção Temporomandibular (DTM. Dessa forma, nosso objetivo foi avaliar o efeito de dez sessões de fisioterapia, exercícios e laserterapia no tratamento da dor muscular e da artralgia em uma mulher com DTM. O alívio médio dos sintomas dolorosos obtidos por sessão foi de 20%, atingindo valor zero nas últimas semanas e mantendo-se estável por 60 dias após o término do tratamento. Os resultados demonstraram que o protocolo de tratamento utilizado foi efetivo no alívio da dor da região articular, assim como da tensão do músculo masseter, levando a paciente a reduzir a ingestão de medicamentos para controle da dor. Entretanto, estudos adicionais são necessários para se definir com maior precisão o efeito de outros programas de fisioterapia, assim como sua interação com as demais modalidades de tratamento.

  16. The comparative analysis of &apos;Regulations on safety of radioactive waste management&apos; of China and federal law &apos;On the management of radioactive waste&apos; of Russian

    International Nuclear Information System (INIS)

    Yang Lili; Zhang Qiao'e; Fan Yun; Liu Ting; Gao Siqi

    2012-01-01

    In this article, the &apos;Regulations on safety of radioactive waste management&apos; of China and Federal Law &apos;On the management of radioactive waste&apos; of Russian were compared, from three aspects: overall legislative ideas, respective unique place and difference of common parts. Refining summed up should learn the contents of the Federal Law &apos;On the management of radioactive waste&apos; of Russian, for the learning exchanges. (authors)

  17. Complicações no tratamento do nasoangiofibroma juvenil com invasão intracraniana

    Directory of Open Access Journals (Sweden)

    Maria Dantas Costa Lima Godoy

    2014-04-01

    Full Text Available Introdução: Apesar de ser uma neoplasia rara, o nasoangiofibroma juvenil (NAJ está associado a elevadas taxas de morbimortalidade e potencial invasão intracraniana. Excisão cirúrgica é o tratamento de escolha. O acesso endoscópico transnasal tem substituído a abordagem cirúrgica externa nas lesões pequenas, podendo ser utilizados de forma conjunta nos casos mais avançados. Objetivo: Deteminar a prevalência de complicações no tratamento cirúrgico endoscópico ou guiado por endoscopia nos NAJ com mínima invasão intracraniana. Método: Trata-se de um estudo retrospectivo realizado nos pacientes com NAJ classe IIIA de Radkowski, com mínima invasão intracraniana, submetidos à cirurgia endoscópica guiada por endoscopia ou acesso cirúrgico externo, entre janeiro de 1996 e maio de 2010. Resultados: No total, 13 pacientes foram submetidos a tratamento cirúrgico. O acesso endoscópico exclusivo foi realizado em três pacientes, sem complicações pós-operatórias. Cirurgia guiada por endoscopia foi realizada em três pacientes, com duas complicações pós-operatórias. Acesso cirúrgico externo foi realizado em sete pacientes. Conclusão: O tratamento cirúrgico do nasoangiofibroma com invasão intracraniana constitui um grande desafio a otorrinolaringologistas e neurocirurgiões. Neste aspecto, os índices de sucesso associado à baixa taxa de complicação intra e pós-operatória parecem ser indicativos de que o acesso endoscópico vem ganhando espaço no manejo do NAJ IIIA da classificação de Radkowski.

  18. Uso de tratamento hidrotérmico e ácido clorídrico na qualidade de lichia 'Bengal'

    Directory of Open Access Journals (Sweden)

    Ellen Toews Doll Hojo

    2011-06-01

    Full Text Available Um dos maiores problemas na pós-colheita da lichia é o escurecimento do pericarpo, cuja cor vermelha se torna totalmente escurecida em 48 horas, sob 25 ºC. Tecnologias que possam controlar o escurecimento do pericarpo são valiosas, e é o foco principal da pesquisa na área de pós-colheita. O objetivo deste trabalho foi avaliar a vida útil de lichias 'Bengal', armazenadas a 20 ºC e 82 %UR após o tratamento hidrotérmico e/ou imersão em solução de HCl. O delineamento experimental foi o inteiramente casualizado, em esquema fatorial 4 x 7, com 3 repetições, onde o primeiro fator correspondeu aos tratamentos: testemunha; imersão em HCl a 1%, por 6 minutos; tratamento hidrotérmico, com imersão em água a 52 ºC por 1 minuto, seguido de resfriamento em água a 10 ºC, por 6 minutos; e tratamento hidrotérmico, seguido de resfriamento em HCl a 1%, a 10 ºC, por 6 minutos. O segundo fator foram os períodos de armazenamento: 0; 1; 2; 3;6; 9 e 12 dias. A combinação entre tratamento hidrotérmico (52 ºC por 1 minuto e resfriamento em HCl a 1% permite conservar a coloração das lichias 'Bengal' por até dois dias. Mesmo assim há escurecimento em 25% da superfície.

  19. The Influence of Teachers&apos; Conceptions on Their Students&apos; Learning: Children&apos;s Understanding of Sheet Music

    Science.gov (United States)

    López-Íñiguez, Guadalupe; Pozo, Juan Ignacio

    2014-01-01

    Background: Despite increasing interest in teachers&apos; and students&apos; conceptions of learning and teaching, and how they influence their practice, there are few studies testing the influence of teachers&apos; conceptions on their students&apos; learning. Aims: This study tests how teaching conception (TC; with a distinction between…

  20. Hepatite crônica por virus C. Parte 2. Tratamento

    Directory of Open Access Journals (Sweden)

    CONTE Vinício Paride

    2000-01-01

    Full Text Available São revistos aspectos relativos às drogas utilizadas, suas dosagens, tempo de duração dos tratamentos, as diferentes respostas terapêuticas obtidas, segundo os vários tipos de doença e de doentes estudados, assim como os fatores que podem modificar os resultados obtidos.

  1. Contributions to the qualification of the &apos;'CRISTAL'&apos; criticality calculi scheme: interpretation of critical experiments. Elaboration of a characterization system of neutronic configurations; Contributions a la qualification du schema de calcul de criticite &apos;'cristal'&apos;: interpretation d&apos;experiences critiques. Elaboration d&apos;un systeme de caracterisation des configurations neutroniques

    Energy Technology Data Exchange (ETDEWEB)

    Gagnier, E

    1999-06-01

    This thesis work is about the validation of the new criticality-safety package CRISTAL and contributes to the modernization and the improvement of the computational tools. The first part presents neutronic elements, the objectives of safety criticality studies and the package CRISTAL. Then, the validation work concerned two series of experiments involving uranyl solutions (UO{sub 2}F{sub 2}) and UO{sub 2} powders. For these experiments, the differences between the computation results and the experimental results were analysed. It was highlighted interesting physical phenomena such of the compensations of errors between the approximate representation by the 99 energy group structure on the first resonance of oxygen and the anisotropy of the diffusion simulation as well as the influence of uranium 234 in high enriched solutions in uranium 235. Once the work of the experimental qualification carried out, raises the question of the use the base of qualification and the &apos;'calculation-experiment'&apos; variations which are referred to it. It is often difficult to establish the link between the &apos;&apos;studied configuration&apos;&apos; and the experiments of the base of qualification. The presented characterisation system proposes to answer in a way automatic and quantified this difficulty: - in bringing an answer on the package qualification for the studied configuration, - in giving an estimate of the package bias. To answer these points, it was defined a set of 35 characteristic neutronic parameters representing the behaviour of the medium. To process the information brought by these parameters and to use it to answer the objectives of the system, we called upon statistical methods (Principal Components Analysis and Sliced Inverse Regression). The results obtained in the feasibility studies showed the relevance of these methods for the considered objectives. (author)

  2. Adesão e não-adesão ao tratamento farmacológico para depressão

    Directory of Open Access Journals (Sweden)

    Marines de Fátima Cunha

    Full Text Available O presente estudo objetivou compreender aspectos relacionados à adesão e a não-adesão ao tratamento farmacológico para depressão, envolvendo usuários e ex-usuários de um serviço público de saúde mental. Foram entrevistados, individualmente, 24 pacientes (12 aderentes e 12 não aderentes ao tratamento medicamentoso para depressão. Por meio da análise de conteúdo das entrevistas, identificou-se que o fenômeno da adesão/não-adesão estaria inter-relacionado a aspectos intrapessoais, interpessoais e ao contexto do tratamento do paciente. Os resultados fomentaram reflexões acerca do papel de equipes de saúde mental no incremento da adesão ao tratamento, bem como da necessidade de uma maior consideração do indivíduo, da família e do atendimento prestado pela instituição.

  3. Perceiving, explaining, and observing climatic changes. An historical case study of the &apos;&apos;year without a summer&apos;&apos; 1816

    Energy Technology Data Exchange (ETDEWEB)

    Bodenmann, Tom; Hirsch Hadorn, Gertrude [ETH Zurich (Switzerland). Inst. for Environmental Decisions; Broennimann, Stefan [Univ. of Bern (Switzerland). Oeschger Centre for Climate Change Research and Inst of Geography; Krueger, Tobias [Staatsarchiv Solothurn (Switzerland); Weissert, Helmut [ETH Zurich (Switzerland). Geological Inst.

    2011-12-15

    The role of the &apos;&apos;year without a summer&apos;&apos; (YWAS) in 1816 in shaping the scientific discourse on climatic changes has been investigated in an interdisciplinary project by studying reactions of different knowledge systems to the YWAS as an initially unexplainable event. The analysis of two Swiss newspapers shows that contemporary science did not play a role in perceiving and dealing with the impacts of the YWAS on the population. Since no climate discipline of its own existed, few contemporary scientist, as we would call those men of science today, were ready to take this situation as an opportunity, reinforcing existing ideas in their domain (e.g. botany, geology, astronomy). Nevertheless, the YWAS did have impacts on science. A &apos;'call'&apos; was issued by the Swiss Natural Sciences Society shortly after the event. The work of one of the respondents became influential for the development of the ice age theory. By revealing a general lack of knowledge on climate, the YWAS might have contributed to the construction of meteorological stations at that time. Some contemporary scientists argued that the cold summer in western Europe was caused by huge masses of ice drifting in the North Atlantic. However, there were no theories that could have linked the exceptionally wet weather in Europe with a volcanic eruption on the other side of the globe. Not before the early 20{sup th} century was the YWAS linked to the Tambora eruption of 1815. After almost two centuries, the YWAS has remained a challenge and source of inspiration. (orig.)

  4. &apos;Lifecycle cost&apos; management used in ITER project

    International Nuclear Information System (INIS)

    Xing Chao; Wu Fengfeng

    2013-01-01

    &apos;Lifecycle cost&apos; management is a new kind of management. The International Nuclear Fusion Energy Program was managing by &apos;lifecycle cost&apos; method. The cost and other factors associated with cost were under control by the method. In the future, the system engineering method should be focused in engineering management, paying equal attention to both evaluation and management, and strengthening the application of information system in the cost management to effectively improve the management level. (authors)

  5. SKI&apos;s and SSI&apos;s review of SKB&apos;s safety report SR-Can

    Energy Technology Data Exchange (ETDEWEB)

    Dverstorp, Bjoern; Stroemberg, Bo (and others)

    2008-03-15

    This report summarises SKI&apos;s and SSI&apos;s joint review of the Swedish Nuclear Fuel and Waste Management Co&apos;s (SKB) safety report SR-Can (SKB TR-06-09). SR-Can is the first assessment of post-closure safety for a KBS-3 spent nuclear fuel repository at the candidate sites Forsmark and Laxemar, respectively. The analysis builds on data from the initial stage of SKB&apos;s surface-based site investigations and on data from full-scale manufacturing and testing of buffer and copper canisters. SR-Can can be regarded as a preliminary version of the safety report that will be required in connection with SKB&apos;s planned licence application for a final repository in late 2009. The main purpose of the authorities&apos; review is to provide feedback to SKB on their safety reporting as part of the pre-licensing consultation process. However, SR-Can is not part of the formal licensing process. In support of the authorities&apos; review three international peer review teams were set up to make independent reviews of SR-Can from three perspectives, namely integration of site data, representation of the engineered barriers and safety assessment methodology, respectively. Further, several external experts and consultants have been engaged to review detailed technical and scientific issues in SR-Can. The municipalities of Oesthammar and Oskarshamn where SKB is conducting site investigations, as well NGOs involved in SKB&apos;s programme, have been invited to provide their views on SR-Can as input to the authorities&apos; review. Finally, the authorities themselves, and with the help of consultants, have used independent models to reproduce part of SKB&apos;s calculations and to make complementary calculations. All supporting review documents are published in SKI&apos;s and SSI&apos;s report series. The main findings of the review are: -SKB&apos;s safety assessment methodology is overall in accordance with applicable regulations, but part of the methodology needs to be

  6. Search for B Meson Decays to eta&apos; eta&apos; K

    Energy Technology Data Exchange (ETDEWEB)

    Aubert, B.

    2006-05-05

    The authors describe searches for decays of B mesons to the charmless final states {eta}&apos;{eta}&apos;K. The data consist of 228 million B{bar B} pairs produced in e{sup +}e{sup -} annihilation, collected with the BABAR detector at the Stanford Linear Accelerator Center. The 90% confidence level upper limits for the branching fractions are {Beta}(B{sup 0} {yields} {eta}&apos;{eta}&apos;K{sup 0}) < 31 x 10{sup -6} and {Beta}(B{sup +} {yields} {eta}&apos;{eta}&apos;K{sup +}) < 25 x 10{sup -6}.

  7. What does &apos;nuclear power village&apos; represent in the newspaper articles?

    International Nuclear Information System (INIS)

    Takenaka, I.; Kimura, H.

    2014-01-01

    Since the Fukushima Daiichi Nuclear Disaster in 2011, we have often heard the word &apos;Nuclear Power Village (Genshiryoku-Mura in Japanese)&apos; in Japan. &apos;Nuclear Power Village&apos; is used for the Japanese community related to nuclear power generation. In this paper, we analysed Japanese newspapers and clarified usages of &apos;Nuclear Power Village&apos;. As a result, we found there are two images of &apos;Nuclear Power Village&apos;. One image has a common purpose of the promotion of nuclear power. Another image has a common purpose of acquiring gain. We also clarified the characteristics of the images such as interdependence, closed community and so on. (author)

  8. What does &apos;nuclear power village&apos; represent in the newspaper articles?

    Energy Technology Data Exchange (ETDEWEB)

    Takenaka, I., E-mail: isshin.takenaka@gmail.com [The Univ. of Tokyo, Tokyo (Japan); Kimura, H., E-mail: kimura.hiroshi.0110@gmail.com [Public Outreach, Non-Profit, Tokyo (Japan)

    2014-07-01

    Since the Fukushima Daiichi Nuclear Disaster in 2011, we have often heard the word &apos;Nuclear Power Village (Genshiryoku-Mura in Japanese)&apos; in Japan. &apos;Nuclear Power Village&apos; is used for the Japanese community related to nuclear power generation. In this paper, we analysed Japanese newspapers and clarified usages of &apos;Nuclear Power Village&apos;. As a result, we found there are two images of &apos;Nuclear Power Village&apos;. One image has a common purpose of the promotion of nuclear power. Another image has a common purpose of acquiring gain. We also clarified the characteristics of the images such as interdependence, closed community and so on. (author)

  9. Swiss &apos;Electricity&apos; Research Programme 2004-2007; Konzept des Forschungsprogramms &apos;Elektrizitaet&apos; 2004 - 2007

    Energy Technology Data Exchange (ETDEWEB)

    Brueniger, R.

    2004-07-01

    This report issued by the Swiss Federal Office of Energy (SFOE) provides details on Swiss research in the electricity area that is foreseen for the period 2004-2007. The report discusses the current state of electricity research and the strategic goals for the period and presents the organisations involved and their previous work. The general main areas of interest addressed by the programme are noted, such as the storage and transport of electricity as well as its use in communication technologies, motors, domestic appliances and industrial applications. Figures are presented on the programme&apos;s finances and the concept of &apos;trend-watching&apos; groups is briefly addressed.

  10. Jevons&apos; paradox

    Energy Technology Data Exchange (ETDEWEB)

    Alcott, Blake [Gretenweg 4, CH 8038 Zurich (Switzerland)

    2005-07-01

    Technological efficiency; Rebound; Impact; Consumption; Growth; Jevons In The Coal Question William Stanley Jevons [Jevons, W.S., 1865/1965. The Coal Question: an Inquiry Concerning the Progress of the Nation, and the Probable Exhaustion of our Coal-mines. 3rd edition 1905, Ed. A.W. Flux. Augustus M. Kelley, New York.] maintained that technological efficiency gains-specifically the more &apos;economical&apos; use of coal in engines doing mechanical work-actually increased the overall consumption of coal, iron, and other resources, rather than &apos;saving&apos; them, as many claimed. Twentieth-century economic growth theory also sees technological change as the main cause of increased production and consumption. In contrast, some ecologically-oriented economists and practically all governments, green political parties and NGOs believe that efficiency gains lower consumption and negative environmental impact. Others doubt this &apos;efficiency strategy&apos; towards sustainability, holding that efficiency gains &apos;rebound&apos; or even &apos;backfire&apos; in pursuing this goal, causing higher production and consumption. Because many environmental problems demand rapid and clear policy recommendations, this issue deserves high priority in ecological economics. If Jevons is right, efficiency policies are counter-productive, and business-as-usual efficiency gains must be compensated for with physical caps like quotas or rationing.

  11. Synthesis, characterization and biological evaluation of a novel &apos;&apos;3+1&apos;&apos; mixed ligand {sup 99m}Tc complex having an aliphatic thiol as coligand

    Energy Technology Data Exchange (ETDEWEB)

    Rey, A. E-mail: arey@bilbo.edu.uy; Papadopoulos, M.; Leon, E.; Mallo, L.; Pirmettis, Y.; Manta, E.; Raptopoulou, C.; Chiotellis, E.; Leon, A

    2001-03-01

    A novel &apos;&apos;3+1&apos;&apos; mixed ligand {sup 99m}Tc complex with N,N-bis(2-mercaptoethyl)-N&apos;N&apos;-diethyl-ethilenediamine as ligand and 1-octanethiol as coligand was prepared and evaluated as potential brain radiopharmaceutical. Preparation at tracer level was accomplished by substitution, using {sup 99m}Tc-glucoheptonate as precursor and a coligand/ligand ratio of 5. Under these conditions the labeling yield was over 80% and a major product with radiochemical purity >80% was isolated by HPLC methods and used for biological evaluation. Chemical characterization at carrier level was developed using the corresponding rhenium and {sup 99g}Tc complexes. Results were consistent with the expected &apos;&apos;3+1&apos;&apos; structure and X-ray diffraction study demonstrated that the complex adopted a distorted trigonal bipyramidal geometry. All sulphur atoms underwent ionization leading to the formation of a neutral compound. Biodistribution in mice demonstrated early brain uptake, fast blood clearance and excretion through hepatobiliary system. Although brain/blood ratio increased significantly with time, this novel {sup 99m}Tc complex did not exhibit ideal properties as brain perfusion radiopharmaceutical since brain uptake was too low.

  12. ISO 3171 production hydrocarbons allocation sampling for challenging &apos;'tie-ins'&apos;with pressures close to RVP breakout

    Energy Technology Data Exchange (ETDEWEB)

    Jiskoot, Mark

    2005-07-01

    There are an increasing number of applications where sampling is required for crude oils and condensates at close to vapour breakout in production environments. These are typified where the quality measurement must be extracted/made in the &apos;'oil'&apos; leg of a separator. The exertion of back pressure (pressure loss) on the liquid leg to expand the operating envelope is generally not acceptable due to the effect that this will have on the separator efficiency and this frequently precludes the use of normal metering technologies. These conditions represent some of the hardest for quality determination. In conventional separators, velocities are low to promote separation of the gas and liquids and the therefore the gas pressure within the liquid phase is close to breakout. Frequently there is an envelope of less than 0.5 bar below the operating pressure at which the fluid will start to cavitate. Concurrent with the low velocity is the expectation of some free water that would require mixing to ensure representativity. There are frequently also severe restrictions on space and the piping arrangement in which to achieve a representative off-take. The &apos;'rules'&apos; that are applied to representative sampling are equally applicable to the use of water monitors (water cut, OWD) and to densitometers. An integrated quality measurement system that prevents any impact on the process and also provides the required mixing to allow extraction of a representative off take that can be used for physical samplers as well as process instrumentation such as densitometers, viscometers and water cut monitors can be achieved by careful design. Jiskoot has adapted its CoJetix technology to meet these goals. (author) (tk)

  13. Estudo da influência do tratamento criogênico no aço AISI H13

    OpenAIRE

    Sandra dos Santos Vales

    2011-01-01

    Há alguns anos, diversos estudos da influência dos parâmetros do tratamento térmico vêm sendo desenvolvidos, para a obtenção de propriedades que permitam atingir os requisitos de trabalho e que gerem ferramentas de vida útil estendida. Nesse contexto, tem sido demonstrado que o tratamento criogênico não só provoca a transformação da austenita residual, trazendo melhorias no dimensional da ferramenta, mas também pode promover a precipitação de carbonetos finos, com ganho em tenacidade e propri...

  14. In LDL receptor-deficient mice, catabolism of remnant lipoproteins requires a high level of apoE but is inhibited by excess apoE

    NARCIS (Netherlands)

    Dijk, K.W. van; Vlijmen, B.J.M. van; Hof, H.B. van 't; Zee, A. van der; Santamarina-Fojo, S.; Berkel, T.J.C. van; Havekes, L.M.; Hofker, M.H.

    1999-01-01

    To investigate the quantitative requirement for apolipoprotein (apo) E in the clearance of lipoproteins via the non-low density lipoprotein (LDL) receptor mediated pathway, human APOE was overexpressed at various levels in the livers of mice deficient for both the endogenous Apoe and Ldlr genes

  15. Scenarios for an integrated sustainability policy - using the example of the &apos;&apos;Sustainable City 2030&apos;&apos;; Szenarien fuer eine integrierte Nachhaltigkeitspolitik - am Beispiel: Die nachhaltige Stadt 2030. Bd. 3. Teilbericht &apos;&apos;Nachhaltiges Wirtschaften in der Stadt 2030&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Grabow, Busso; Hollbach-Groemig, Beate; Groepler, Nicolai; Rechenberg, Christoph [Deutsches Inst. fuer Urbanistik (DiFu), Berlin (Germany); Gassner, Robert [Institut fuer Zukunftsstudien und Technologiebewertung gGmbH (IZT), Berlin (Germany)

    2013-04-15

    The partial report,Sustainability economic activity in the City 2030&apos; was performed as a part of a project of the Federal Environment Agency (Dessau-Rosslau, Federal Republic of Germany) entitled &apos;Scenarios for an integrated sustainability policy - exemplified by using,Sustainable City 2030&apos;&apos;. The objectives of this partial report are: (a) Presentation of the topic and its importance in the current debate on sustainability; (b) Answering the questions: What are the interfaces to the municipal level? What is about the capability of acting at the municipal level? Which framework conditions are necessary on the part of the Federal Government and the State Governments?; (c) Rough outline of the current situation; (d) Outlining the opportunities and perspectives up to the implementation of the sustainable economic activity.

  16. &apos;Atomic Bremsstrahlung&apos;: Retrospectives, current status and perspectives

    Energy Technology Data Exchange (ETDEWEB)

    Amusia, M.Ya. [Racah Institute of Physics, Hebrew University, Jerusalem 91904 (Israel) and Ioffe Physical-Technical Institute, St. Petersburg 194021 (Russian Federation)]. E-mail: Amusia@vms.huji.ac.il

    2006-10-15

    We describe here the &apos;Atomic bremsstrahlung&apos; (AB)-emission of continuous spectrum electromagnetic radiation, which is generated in collisions of particles that have internal deformable structure that includes positively and negatively charged constituents. The deformation of one or both colliding partners induces multiple, mainly dipole, time-dependent electrical moments that become a source of radiation. The history of AB invention is presented and its unusual in comparison to ordinary bremsstrahlung (OB) properties, are discussed. As examples, fast electron atom, non-relativistic and relativistic collisions are considered. Attention is given to ion-atom and atom-atom collisions. Specifics of &apos;elastic&apos; and &apos;inelastic&apos; (i.e. radiation accompanied by destruction of collision partners) AB will be mentioned. Attention will be given to possible manifestation of AB in nature and in some exotic systems, for instance scattering of electrons upon muonic hydrogen. Some cooperative effects connected to AB will be considered. New classical schemes similar to AB will be presented.

  17. Avaliação do tempo para acesso ao tratamento do câncer de mama no Distrito Federal

    OpenAIRE

    Barros, Ângela Ferreira [UNESP

    2011-01-01

    A alta taxa de mortalidade do câncer de mama em países em desenvolvimento é associada à falta de programas de detecção precoce, ao retardo no diagnóstico e tratamento, bem como às dificuldades para acesso aos serviços de saúde. O objetivo desse estudo foi identificar artigos que associaram o retardo no diagnóstico e tratamento com a evolução do câncer de mama, verificar os fatores associados ao atraso e apontar sugestões para minimizar o atraso no diagnóstico e tratamento do câncer de mama. F...

  18. Conhecimento de pediatras que atuam em urgências e emergências sobre tratamento da anafilaxia

    Directory of Open Access Journals (Sweden)

    João Carlos Pina Faria

    2018-05-01

    Full Text Available Introdução: Anafilaxia é uma reação sistêmica grave, aguda e potencialmente fatal. Apresenta vários desencadeantes e mecanismos diferentes, entretanto, o tratamento agudo é igual em todos os casos. Objetivo: Avaliar o conhecimento sobre tratamento da anafilaxia e choque anafilático (CA de pediatras que atuam em setor de emergência pediátrica. Métodos: Estudo transversal através da aplicação de questionário de múltiplas escolhas com 10 perguntas sobre tratamento da anafilaxia e CA. Foram convidados todos os pediatras do Pronto Socorro de um Hospital Público Pediátrico. Resultados: Cinquenta entre 51 pediatras concordaram em participar do estudo. A média de acertos foi 6,32 com mediana de 7 (mínimo 2 e máximo 10. Houve reconhecimento adequado dos pediatras sobre a droga de escolha para iniciar o tratamento da anafilaxia e CA em 96% e 92%, respectivamente. Sobre a via de administração da adrenalina, a adequação das respostas foi de 64%. Em relação à dose de adrenalina, 70% identificaram corretamente, porém, o conhecimento sobre a dose máxima foi de 44%. Ao perguntar o intervalo para repetir a adrenalina, 38% responderam corretamente. Perguntou-se sobre terapias adjuvantes no tratamento do CA com 74% de acerto. Sobre a droga que previne a reação anafilática bifásica, 60% responderam corretamente. Quanto ao tempo de observação, 54% responderam o período adequado. O acerto sobre apresentações disponíveis de adrenalina autoinjetável foi de 40%. Conclusão: Houve dificuldade principalmente em reconhecer dose máxima, dose de adrenalina autoinjetável e tempo necessário para ser repetida, o que aumenta o risco de superdosagem e seus efeitos adversos.

  19. Thermal management of a &apos;'BC'&apos; size molicel

    Energy Technology Data Exchange (ETDEWEB)

    Fouchard, D.; Ruggier, L.; Taylor, B.J.

    1987-05-01

    The &apos;'BC'&apos; size MOLICEL using the rechargeable system Li/MoS/sub 2/ has already been shown to have performance characteristics appropriate for use in an electric vehicle battery. The cell design, based on the results of thermal modelling studies, has been modified to provide for improved removal of waste heat resulting from planned high power discharge or from accidental electrical abuse. Experimental verification of the various interfacial thermal impedances was done and an appropriate heat sink specified to use air cooling for the final rejection stage. Fully instrumented 45 Ah test cells were built using a design in which waste heat was caused to flow axially in the aluminum foils forming the cathode current collector. The bottom ends of these foils were thermally integrated to the cell can bottom which had air cooling fins attached externally. Two fully charged cells of this special design were subjected to sustained short circuit whilst being cooled on their fins only with air at 25 km/h. Neither cell experienced any excessive heat built-up and no safety hazard occurred. The results show that thermal management of this type of battery can readily be done using a simple cell design modification and requiring minimum complexity for heat disposal to the environment. The system does not impose any extraordinary constraints on electric vehicle design and it would also be feasible to duct warm air from the battery heat exchanger to provide passenger compartment heating. 17 figs., 7 tabs.

  20. Re-evaluation of the criticality experiments of the &apos;&apos;Otto Hahn Nuclear Ship&apos;&apos; reactor

    Energy Technology Data Exchange (ETDEWEB)

    Lengar, I.; Snoj, L.; Rogan, P.; Ravnik, M. [Jozef Stefan Institute, Ljubljana (Slovenia)

    2008-11-15

    Several series of experiments with a FDR reactor (advanced pressurized light water reactor) were performed in 1972 in the Geesthacht critical facility ANEX. The experiments were performed to test the core prior to its usage for the propulsion of the first German nuclear merchant ship &apos;'Otto-Hahn'&apos;. In the present paper a calculational re-evaluation of the experiments is described with the use of the up-to date computer codes (Monte-Carlo code MCNP5) and nuclear data (ENDF/B-VI release 6). It is focused on the determination of uncertainties in the benchmark model of the experimental set-up, originating mainly from the limited set of information still available about the experiments. Effects of the identified uncertainties on the multiplication factor were studied. The sensitivity studies include parametric variation of material composition and geometry. The combined total uncertainty being found 0.0050 in k{sub eff}, the experiments are qualified as criticality safety benchmark experiments. (orig.)

  1. Resonant light power buildup in ALPS, a &apos;&apos;light shining through a wall&apos;&apos;-experiment

    Energy Technology Data Exchange (ETDEWEB)

    Meier, Tobias; Danzmann, Karsten; Willke, Benno [Max-Planck-Institut fuer Gravitationsphysik, Albert Einstein Institut (Germany); Institut fuer Gravitationsphysik, Leibniz Universitaet Hannover, Callinstrasse 38, D-30167 Hannover (Germany); Ehret, Klaus; Ghazaryan, Samvel; Knabbe, Axel; Lindner, Axel; List, Jenny; Meyer, Niels; Notz, Dieter; Redondo, Javier; Ringwald, Andreas [Deutsches Elektronen-Synchrotron DESY, Notkestrasse 85, D-22607 Hamburg (Germany); Frede, Maik; Hildebrandt, Matthias [Laserzentrum Hannover e.V., Hollerithallee 8, D-30419 Hannover (Germany); Wiedemann, Guenter [Hamburger Sternwarte, Gojenbergsweg 112, D-21029 Hamburg (Germany)

    2009-07-01

    We report on the first successfull application of a new experimental technique to search for weakly interacting sub-eV particles (WISPs) coupling to photons. As part of the ALPS experiment located at DESY in Hamburg, this technique uses an optical resonator to enhance the power inside a HERA dipole magnet on the production side of a typical &apos;&apos;light shining through a wall&apos;&apos;-experiment. We use a frequency doubled continuous-wave laser emitting 0.6 W of power at 532 nm that is stabilized to a linear optical resonator with 8 m length. On resonance we achieve a circulating power of 34 W within the magnet. With this we obtained sensitivities corresponding to a coupling strength of g{approx}5.10{sup -7} GeV{sup -1} for interactions of axion-like particles and photons. The experimental setup and possible improvements are described and compared with common experimental designs with pulsed lasers.

  2. Breeding ground: evolving the &apos;smart&apos; industry

    Energy Technology Data Exchange (ETDEWEB)

    Jaremko, G.

    2001-05-01

    This article celebrates the successes of the Canadian independent oil contractors and the oilfield service and supply sector that keep Canada in the forefront of the world&apos;s &apos;smart&apos; nations in energy stewardship, efficiency, development, diversification and utilization. It explains how small independent contractors and service and supply enterprises play a central role on all these fronts, with supply and service companies being responsible for about 80 per cent of oil companies&apos; capital budget and 70 per cent of their operational expenditures in fields ranging from construction, and camp catering, to ambulance services, safety systems, trucking, tool making, drilling services, production testing, valve manufacturing, chemical blending and environmental protection. Special attention is paid to importance on independent contractors represented by the Small Explorers and Producers Association of Canada (SEPAC), their ability to develop or adopt new technology and to accommodate the demands of constantly changing price levels and increasingly higher expectations in terms of social responsibility, productivity and competitiveness, as well as environmental performance. As an example, the article describes the career of Robert Tessari, founder and president of Tesco Corporation, a drilling company operating in some 40 countries, who aims to automate drilling to the point where rig crews are pared to teams of two or three experts directing machinery from computer consoles. That he is well on the way of achieving his objectives is illustrated by his contributions to the development of a new generation of bits, tools and procedures known as the &apos;case drilling&apos; process which simultaneously uses the same steel tubing to make the holes into oil and gas-bearing formations and line them for production, and in so doing cut 25 to 30 per cent off the time required to drill a well and bring it to production. His company&apos;s contribution to the

  3. Ecological crisis: The &apos;Chernobyl feeling&apos; - or how the mental effects of the ecological disaster can be detected and &apos;measured&apos;. Umweltkrise: Das &apos;Tschernobyl-Gefuehl&apos; - wie die psychischen Folgen der oekologischen Krise &apos;vermessen&apos; werden

    Energy Technology Data Exchange (ETDEWEB)

    Boehm, A.; Boehnke, K.; Boldt, P.R.; Faas, A.; Gross, B.; Jaeggi, E.; Legewie, H.

    1989-10-01

    Given real personal embarrassment, the Chernobyl accident indeed has had an impact on the vital consciousness, and this effect has been developing in two phases, an initial phase, and a subsequent phase characterised by mental digestion. In the initial, post-accident phase, the typical &apos;Chernobyl feeling&apos; is frequently predominant. If this feeling later is weakened or diluted by a back-to-normal attitude, no bearing effects on vital consciousness or identity feeling can be observed, but a general feeling of pessimism and resignment remains. If, however, &apos;normalisation&apos; did not set in until the first interview in this study, personal identity is found to be undergoing a change. A more conscious apprehension of life can be observed, a change in life style up to political commitment, or also leading to a determined turn to short-term, private compensating activities, (last-minute panic). (orig./HP).

  4. Cerebrospinal fluid leakage. Indications, technique and results of treatment with a blood patch; Liquorverlustsyndrom. Indikation, Technik und Ergebnisse der Behandlung mit &apos;&apos;blood patch&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Gottschalk, A. [Krankenhaus Nordwest, Abteilung Neuroradiologie, Frankfurt am Main (Germany)

    2015-06-15

    of several months, even though patients are already free of symptoms. In total, blood patch therapy is a safe and technically relative simple method with a high success rate. Therefore, it represents the therapy of choice in patients with spontaneous cerebrospinal fluid leakage as well as in cases of post-lumbar puncture syndrome refractory to conservative therapy. (orig.) [German] In den meisten Faellen ist ein Liquorverlustsyndrom iatrogen durch Lumbalpunktionen, Periduralanaesthesien oder operative Eingriffe an der Wirbelsaeule bedingt. Durch verbesserte diagnostische Moeglichkeiten werden jedoch auch spontane Liquorverlustsyndrome mit zunehmender Haeufigkeit diagnostiziert, deren Ursache oft nicht eindeutig zu klaeren ist. Zur radiologischen Diagnosesicherung und zur Lokalisierung des Liquorlecks stehen mit der Postmyelo-CT, der {sup 111}Indium-Radioisotopenzisternographie und der (Myelo-)MRT mehrere Verfahren mit unterschiedlichen Sensitivitaeten zur Verfuegung. Nach unserer eigenen Erfahrung ist eine primaer nativdiagnostische MRT mit fettsaturierten T2-Sequenzen in vielen Faellen bereits diagnostisch ausreichend, um das Liquorleck und seine Lokalisation zu sichern. In den uebrigen Faellen ist die Durchfuehrung einer ergaenzenden Postmyelo-CT oder alternativ einer Myelo-MRT empfehlenswert. Bei manchen Patienten mit spontanem Liquorverlustsyndrom finden sich dabei mehrere Liquorlecks auf unterschiedlichen Hoehen. Leitsymptom ist in den meisten Faellen ein lageabhaengiger orthostatischer Kopfschmerz. Waehrend das postpunktionelle Syndrom unter Bettruhe und medikamentoeser Therapie oft selbstlimitierend ist, bedarf es beim spontanen Liquorverlustsyndrom meist einer Blood-patch-Therapie. Der lumbale &apos;&apos;blood patch&apos;&apos; kann in der Regel problemlos unter Durchleuchtungskontrolle erfolgen. Bei einem &apos;&apos;blood patch&apos;&apos; an der HWS oder BWS wird aus Sicherheitsgruenden eine CT-gesteuerte Durchfuehrung empfohlen, um eine streng epidurale

  5. &apos;'Spin-dependent'&apos; μ → e conversion on light nuclei

    International Nuclear Information System (INIS)

    Davidson, Sacha; Saporta, Albert; Kuno, Yoshitaka

    2018-01-01

    The experimental sensitivity to μ → e conversion will improve by four or more orders of magnitude in coming years, making it interesting to consider the &apos;'spin-dependent'&apos; (SD) contribution to the rate. This process does not benefit from the atomic-number-squared enhancement of the spin-independent (SI) contribution, but probes different operators. We give details of our recent estimate of the spin-dependent rate, expressed as a function of operator coefficients at the experimental scale. Then we explore the prospects for distinguishing coefficients or models by using different targets, both in an EFT perspective, where a geometric representation of different targets as vectors in coefficient space is introduced, and also in three leptoquark models. It is found that comparing the rate on isotopes with and without spin could allow one to detect spin-dependent coefficients that are at least a factor of few larger than the spin-independent ones. Distinguishing among the axial, tensor and pseudoscalar operators that induce the SD rate would require calculating the nuclear matrix elements for the second two. Comparing the SD rate on nuclei with an odd proton vs. odd neutron could allow one to distinguish operators involving u quarks from those involving d quarks; this is interesting because the distinction is difficult to make for SI operators. (orig.)

  6. &apos;'Spin-dependent'&apos; μ → e conversion on light nuclei

    Energy Technology Data Exchange (ETDEWEB)

    Davidson, Sacha; Saporta, Albert [IPNL, CNRS/IN2P3, Villeurbanne (France); Universite Claude Bernard Lyon 1, Villeurbanne (France); Universite de Lyon, Lyon (France); Kuno, Yoshitaka [Osaka University, Department of Physics, Toyonaka, Osaka (Japan)

    2018-02-15

    The experimental sensitivity to μ → e conversion will improve by four or more orders of magnitude in coming years, making it interesting to consider the &apos;'spin-dependent'&apos; (SD) contribution to the rate. This process does not benefit from the atomic-number-squared enhancement of the spin-independent (SI) contribution, but probes different operators. We give details of our recent estimate of the spin-dependent rate, expressed as a function of operator coefficients at the experimental scale. Then we explore the prospects for distinguishing coefficients or models by using different targets, both in an EFT perspective, where a geometric representation of different targets as vectors in coefficient space is introduced, and also in three leptoquark models. It is found that comparing the rate on isotopes with and without spin could allow one to detect spin-dependent coefficients that are at least a factor of few larger than the spin-independent ones. Distinguishing among the axial, tensor and pseudoscalar operators that induce the SD rate would require calculating the nuclear matrix elements for the second two. Comparing the SD rate on nuclei with an odd proton vs. odd neutron could allow one to distinguish operators involving u quarks from those involving d quarks; this is interesting because the distinction is difficult to make for SI operators. (orig.)

  7. Energy-related renovation in the world heritage. Retrofitting &apos;Glas-Hoffmann&apos; buildings, Berlin; Energetische Sanierung im Weltkulturerbe. Sanierung &apos;Glas-Hoffmann&apos;-Bauten, Berlin

    Energy Technology Data Exchange (ETDEWEB)

    Brensing, Christian

    2012-11-01

    Between 1955 and 1959, the housing estate at the Schiller park in Berlin-Wedding (Federal Republic in Germany) established in the 1920ies was expanded by four-storey house lines, the so-called Glas-Hoffmann buildings. Since 2008, this ensemble belongs to the Unesco World Heritage. In improving the thermal insulation of the building envelope and the adaptation of the building services to today&apos;s standards, therefore the architectural aesthetics of these buildings should not be endangered. The retrofitting was a pilot project of the research project &apos;&apos;Monument and energy - Postwar Modernism&apos;&apos;.

  8. Exergonic-economic analysis of the &apos;Sotacib&apos; cement baking unit; Analyse exergeco-economique de l&apos;atelier de cuisson de la cimenterie &apos;Sotacib&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Gharsalli, A.; Barkati, M. [Sotacib, Feriana (Tunisia); Hajji, N.; Gaabab, A.; Jeday, M.R. [Ecole Nationale d' ingenieurs de Gabes (Tunisia)

    1999-07-01

    The main purpose of this work is the development of a computing tool for the exergetic analysis of a cement baking unit belonging to the &apos;Societe Tuniso-Algerienne de Ciment Blanc (SOTACIB)&apos;. We chose to study this unit in particular because it accounts for about 30 to 60 % of the total cement production costs. The developed program, called &apos;CIMEX&apos;, its capable of computing mass and energy balances and estimating the exergetic losses and efficiencies associated with the main operations of the studied unit. The results of the exergetic analysis were used to study the economic impact of recovering some of the energetic reserves in order to improve the efficiency of the baking unit which will make the subject of another article. (authors)

  9. Pythagoras&apos;s theorem on a two-dimensional lattice from a &apos;natural&apos; Dirac operator and Connes&apos;s distance formula

    Energy Technology Data Exchange (ETDEWEB)

    Dai Jian [Theory Group, Department of Physics, Peking University, Beijing (China)]. E-mail: jdai@mail.phy.pku.edu.cn; Song Xingchang [Theory Group, Department of Physics, Peking University, Beijing (China)]. E-mail: songxc@ibm320h.phy.pku.edu.cn

    2001-07-13

    One of the key ingredients of Connes&apos;s noncommutative geometry is a generalized Dirac operator which induces a metric (Connes&apos;s distance) on the pure state space. We generalize such a Dirac operator devised by Dimakis et al, whose Connes distance recovers the linear distance on an one-dimensional lattice, to the two-dimensional case. This Dirac operator has the local eigenvalue property and induces a Euclidean distance on this two-dimensional lattice, which is referred to as &apos;natural&apos;. This kind of Dirac operator can be easily generalized into any higher-dimensional lattices. (author)

  10. Tratamentos farmacológicos para o transtorno de ansiedade social: existem novos parâmetros na atualidade?

    Directory of Open Access Journals (Sweden)

    Larissa Forni dos Santos

    2011-01-01

    Full Text Available CONTEXTO: O transtorno de ansiedade social (TAS, apesar da baixa taxa de detecção e do alto índice de comorbidades associadas, é considerado uma condição tratável. Apesar da resposta estabelecida a diversas classes de medicamentos, os algoritmos para o tratamento do TAS necessitam de atualização constante. OBJETIVO: Realizar revisão sistemática da literatura no que diz respeito à eficácia dos tratamentos farmacológicos relativos ao TAS, a partir de estudos controlados, conduzidos no período de 2005 a 2010. MÉTODO: Foram utilizados os indexadores eletrônicos PsycoInfo, Lilacs e Medline, utilizando-se as palavras-chave: "social phobia or social anxiety and treatment". RESULTADOS: De acordo com critérios de inclusão adotados, 29 artigos foram incluídos e analisados. Mostram-se eficazes para o tratamento do TAS as seguintes drogas, de acordo com a classe: a ISRSs: escitalopram, fluvoxamina, citalopram, GR205171 e sertralina; b ISRSN: venlafaxina; c IMAOs: fenelzina, moclobemina; d aminoácidos: d-cicloserina; f anticonvulsivantes: tiagabina. CONCLUSÃO: Os ISRSs e os ISRSNs têm seu uso estabelecido e ainda continuam sendo considerados primeira opção de tratamento. Porém, destaca-se o potencial futuro da d-cicloserina e dos anticonvulsivantes, com necessidade de um número maior de estudos controlados que confirmem os achado iniciais. A ação das diferentes drogas em nível neurobiológico, bem como dos tratamentos associados, necessita ainda ser mais explorada.

  11. Sistema de criação de rotas automotivas virtuais para o tratamento de fobias de direção

    OpenAIRE

    Paiva, José Gustavo de Souza

    2006-01-01

    A Realidade Virtual é uma técnica computacional que permite ao usuário imersão, interação e navegação em ambientes virtuais que simulam situações da vida real. Por este motivo, sua utilização em diversas áreas do conhecimento é muito promissora, em especial na Psicologia, para o tratamento de fobias. Para o tratamento da fobia de direção, estas características podem também trazer benefícios. Existem diversos sistemas que utilizam a Realidade Virtual para o tratamento de fobias ...

  12. &apos;'Affenhaar'&apos; revisited - Facies context of in situ preserved latex from the Middle Eocene of Central Germany

    Energy Technology Data Exchange (ETDEWEB)

    Wilde, Volker [Senckenberg Forschungsinstitut und Naturmuseum, Sektion Palaeobotanik, Senckenberganlage 25, 60325 Frankfurt am Main (Germany); Riegel, Walter [Senckenberg Forschungsinstitut und Naturmuseum, Sektion Palaeobotanik, Senckenberganlage 25, 60325 Frankfurt am Main (Germany); Geowissenschaftliches Zentrum der Universitaet Goettingen, Geobiologie, Goldschmidtstr. 3, 37077 Goettingen (Germany)

    2010-08-01

    In situ preserved latex (&apos;'Affenhaar'&apos;) has long been known from some of the Middle Eocene lignites of Central Germany. Now, for the first time, the occurrence of bark with latex canals still in situ has been studied in detail in the former mining area of the Geiseltal. Affenhaar is found in both massive matrix-dominated lignites and interbedded clastics, representing sub-autochthonous and reworked material, respectively. Palynological studies of Affenhaar-bearing sections reveal a highly diverse assemblage of spores and pollen, but none of the pollen taxa is obviously correlated to the occurrence of Affenhaar. A significant herbaceous component has been recognized in the pollen record in addition to those taxa mainly derived from trees. (author)

  13. Change of radiation conditions at the &apos;'Ukryttya&apos; object after pitching of arch construction

    International Nuclear Information System (INIS)

    Jegorov, V.V.; Morozov, Yu.V.; Pavlovs'kij, L.Yi.; Kholodyuk, A.O.

    2017-01-01

    Individual measurements of dose rate (DR) capacity values were performed on the outer surfaces (roof) of object &apos;'Ukryttya'&apos;, in local zone both before and after pitching of Arch construction (Arch) as well as study the characteristics of angular distribution of gamma radiation intensity at those areas. A comparative analysis of results obtained was performed. At all measuring points after Arch pitching a reduction of DR value, depending on area of research, was observed.Measurements were being performed during the period from 16.11.2016 till 18.01.2017

  14. Sampling system for fast single pulses; Realisation d&apos;un dispositif d&apos;echantillonnage d&apos;un signal bref unique

    Energy Technology Data Exchange (ETDEWEB)

    Zenatti, D. [Commissariat a l' Energie Atomique, Grenoble (France). Centre d' Etudes Nucleaires

    1969-07-01

    Development of a device for the enlargement of the domain of application of classical oscilloscopes to the observation of fast single pulses by application of the sampling principle. Its principal characteristics are: Bandwidth of 700 MHz; Maximum sensibility of 50 mV; Maximum amplitude of input signal of {+-} 1 V; Number of samples of 16; Samples separation of 0,2 ns. (author) [French] Realisation d&apos;un dispositif permettant d&apos;elargir le domaine d&apos;utilisation des oscilloscopes classiques en appliquant le principe de l&apos;echantillonnage a l&apos;observation d&apos;un signal bref unique. Les principales caracteristiques sont les suivantes: Bande passante de 700 MHz; Sensibilite maximale de 50 mV; Amplitude maximale du signal a echantillonner de {+-} 1 V; Nombre de points d&apos;echantillonnage de 16; Pas d&apos;echantillonnage de 0,2 ns. (auteur)

  15. High-speed ping-pong tables. Does the &apos;World Solar Challenge&apos; feature the cars of the future? Rather not.; Rasende Tischtennisplatten. Fahren bei der &apos;&apos;World Solar Challenge&apos;&apos; die Autos der Zukunft? Eher nicht

    Energy Technology Data Exchange (ETDEWEB)

    Siemer, Jochen

    2011-10-15

    The 11th &apos;World Solar Challenge&apos; started in mid-October 2011. This a race of solar cars across Australia is the most spectacular of its kind, but it is hardly a test for solar cars of the future as the regulations for racing cars are far from those for everyday electric-powered solar vehicles. A normal-looking car like the &apos;Solarworld GT&apos; developed at Bochum university therefore has no real chance of winning, however proud its designers may be.

  16. The &apos;&apos;Cobalt 60 Case&apos;&apos; in Taiwan. Conclusions; Das Kobalt-60 Ereignis von Taiwan. Und was ist daraus zu schliessen?

    Energy Technology Data Exchange (ETDEWEB)

    Niemann, Lutz

    2017-08-15

    The &apos;&apos;Cobalt 60 Case&apos;&apos; in Taiwan gives an opportunity for check of the thesis of radiation hormesis. Apartment residents have been exposed to cobalt-60 contaminated steel buildings. The results of a study strongly suggest that whole-body chronic irradiation, in the dose rate range that the apartment residents received, caused no symptomatic adverse health effects, such as radiation sickness, or the increased cancer or increased congenital disease that are predicted by ICRP theories. On the contrary, those who were exposed had lower incidences of cancer mortality and congenital malformations.

  17. Final report of phase 2 &apos;Mini-cogeneration in the flower bulb industry&apos;; Eindrapportage Fase 2 &apos;Mini-WKK in de bloembollensector&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Koolwijk, E. [Cogen Projects, Driebergen-Rijsenburg (Netherlands); Smailbegovic, N. [SenterNovem, Utrecht (Netherlands)

    2009-09-15

    Phase 2 of the project &apos;mini-cogeneration in the flower bulb industry&apos; is the sequel to the report &apos;mini-cogeneration in the flower bulb industry. Use of cogeneration in the cultivation and hot bed of tulip and hyacinth&apos;, Addressing the incentivisation of the use of cogeneration in the sector and working toward realizing a number of demonstration projects. To this end it is necessary that potential investors are given insight in the feasibility of cogeneration at their business and that their enthusiasm is kindled for the use of cogeneration. This was done by disseminating information in the flower bulb industry about the opportunities of cogeneration and by informing growers about technique, economy and points of interest. [Dutch] Fase 2 van het project &apos;Mini- WKK in de bloembollensector&apos; is een vervolg op het rapport &apos;Mini-wkk in de bloembollensector. Toepassing van wkk bij teelt en broei van tulp en hyacint&apos; en richt zich op het stimuleren van de toepassing van WKK in de sector en toewerken naar realisatie van een aantal demonstratieprojecten. Daartoe is het noodzakelijk dat potentiele investeerders inzicht krijgen over de haalbaarheid van WKK op hun bedrijf en geenthousiasmeerd worden voor het gebruik van WKK. Dit is gedaan door informatie in de bollensector te verspreiden over de mogelijkheden van WKK en telers te informeren over techniek, economie en aandachtspunten.

  18. Hunger for carbon dioxide. Foundation of the &apos;Task Force Biomass&apos; for the development of new energy sources; Hunger nach Kohlendioxid. &apos;Task Force Biomasse&apos; zur Erschliessung neuer Energiequellen gegruendet

    Energy Technology Data Exchange (ETDEWEB)

    Schlaefer, Susanne; Bayer, Thomas [Infraserv GmbH und Co. Hoechst KG, Frankfurt am Main (Germany)

    2009-10-15

    At the industrial park Hoechst (Frankfurt / Main, Federal Republic of Germany), Infraserv GmbH and Co. Hoechst KG pursues the disposal conception &apos;&apos;Waste to Energy&apos;&apos; in order to supply electricity and steam for the approximately 90 producing companies at the location. The company now looks for possibilities in order to develop new energy sources. The keyword is &apos;&apos;innovative biomass&apos;&apos;. Among other things the possibility of power generation from algae belongs to this.

  19. Records of the Chernobyl court. Excerpts from Karpan&apos;s book &apos;Revenge of Peaceful Atom&apos;

    International Nuclear Information System (INIS)

    Hirano, Shin-ichiro

    2013-01-01

    The trial took place in July 1987, and it was a speedy trial of three weeks until the ruling from indictment reading. The court was virtually &apos;closed.&apos; The accused were the following 6 persons: Director of Chernobyl NPP, power plant chief engineer, power plant deputy chief engineer, second reactor work center chief, Chernobyl NPP National Nuclear Energy Supervisory Board inspector, and power plant night shift chief. Court records or court documents have not officially published as of March 2013. These court records have been reconstructed from the memos of Nikolay Karpan (Chernobyl NPP nuclear safety ex-deputy chief engineer), who recorded them at a time when he appeared in the court as a witness, and when he attended the court for hearing. The impressions of the translator are as follows. (1) The first purpose of the trial was to promptly punish responsible persons, and to put an end to the accident. (2) Emphasis was not placed on the investigation of the accident cause or accident background. (3) As Mr. Karpan pointed out, this trial gave impression that it was &apos;farce&apos; according to certain &apos;scenario&apos; or &apos;fixed game&apos; that was held in order to conclude that the accident was caused by the sins of accused persons. As for the defects of the nuclear reactor as the defendants pointed out, they were dismissed as &apos;separate issues to be addressed,&apos; and eliminated from judgment contents. (4) All the accused denied the indictment contents (asserting the inadequacy of the reactor itself, deficiencies of regulations and documentations, and deficit of authority). However, they admitted the moral responsibility for being unable to prevent the accident. All the defendants received actual prison term of 2 to 10 years with correctional labor. (A.O.)

  20. Diagnóstico e tratamento de epilepsia e crises pseudoepilépticas psicogênicas associadas: relato de caso

    Directory of Open Access Journals (Sweden)

    Marchetti Renato Luiz

    2001-01-01

    Full Text Available Relatamos o caso de uma paciente de 26 anos em que é evidenciada a importância médica do diagnóstico diferencial entre epilepsia e crises pseudo-epilépticas psicogênicas (CPEP e do seu tratamento. A paciente, uma professora desempregada, com crises desde os 13 anos, foi encaminhada ao PROJEPSI para diagnóstico e tratamento de CPEP. Seu diagnóstico inicial foi de epilepsia parcial sintomática por lesão tumoral cística em região occipto-temporal esquerda, associada a CPEP. Submetida a craniotomia occipital com ressecção de processo expansivo em região de istmo do cíngulo, evoluiu com persistência das CPEP. Submetida a tratamento psicológico integrado envolvendo técnicas de condicionamento operante, manejo de ansiedade, sugestão e orientação familiar, houve remissão completa das CPEP após 4 meses de tratamento. O caso apresentado demonstra a necessidade de múltiplos procedimentos diagnósticos e terapêuticos e a participação de equipe multidisciplinar especializada.

  1. RNA-Seq Mouse Brain Regions Expression Data Analysis: Focus on ApoE Functional Network

    Directory of Open Access Journals (Sweden)

    Babenko Vladimir N.

    2017-09-01

    Full Text Available ApoE expression status was proved to be a highly specific marker of energy metabolism rate in the brain. Along with its neighbor, Translocase of Outer Mitochondrial Membrane 40 kDa (TOMM40 which is involved in mitochondrial metabolism, the corresponding genomic region constitutes the neuroenergetic hotspot. Using RNA-Seq data from a murine model of chronic stress a significant positive expression coordination of seven neighboring genes in ApoE locus in five brain regions was observed. ApoE maintains one of the highest absolute expression values genome-wide, implying that ApoE can be the driver of the neighboring gene expression alteration observed under stressful loads. Notably, we revealed the highly statistically significant increase of ApoE expression in the hypothalamus of chronically aggressive (FDR < 0.007 and defeated (FDR < 0.001 mice compared to the control. Correlation analysis revealed a close association of ApoE and proopiomelanocortin (Pomc gene expression profiles implying the putative neuroendocrine stress response background of ApoE expression elevation therein.

  2. Hawai&apos;i&apos;s EVolution: Hawai&apos;i Powered. Technology Driven. (Brochure)

    Energy Technology Data Exchange (ETDEWEB)

    2013-05-01

    This Hawaii Clean Energy Initiative (HCEI) brochure outlines Hawaii&apos;s energy and transportation goals and the implementation of electric vehicles (EV) and electric vehicle infrastructure since HCEI began in 2008. It includes information about Hawaii&apos;s role in leading the nation in available EV charging infrastructure per capita; challenges for continuing to implement EV technology; features on various successful EV users, including the Hawaiian Electric Company, Enterprise Rent-A-Car, and Senator Mike Gabbard; how EVs can integrate into and help propel Hawaii&apos;s evolving smart grid; and much more.

  3. The fifth international symposium &apos;&apos;atomic cluster collisions&apos;&apos;. ISACC 2011. Book of Abstracts

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2011-07-01

    The Fifth International Symposium &apos;&apos;Atomic Cluster Collisions&apos;&apos; (ISACC 2011) will take place in July 21-25, 2011 in Berlin, Germany. The venue of the meeting will be the St.-Michaels-Heim a lovely place located within a garden area of Berlin-Grunewald. The ISACC 2011 is organized by the Fritz-Haber-Institute of the Max- Planck Society along with the King Saud University, Rhiyadh and by the Frankfurt Institute for Advanced Studies (FIAS), Frankfurt am Main, Germany. ISACC started as the international symposium on atomic cluster collisions in St. Petersburg, Russia in 2003. The second ISACC was held at the GSI, Darmstadt, Germany in 2007. Both first and second symposia were satellites of the International Conferences on Photonic Electronic and Atomic Collisions (ICPEAC). The third ISACC has returned to St. Petersburg, Russia in 2008. The last ISACC took place in Ann Arbor, again as a satellite meeting of the ICPEAC. Initially the symposium was mainly focused on dynamics of atomic clusters, especially in atomic cluster collisions, but since then its scope has been widened significantly to include dynamics of nanosystems, biomolecules, and macromolecules with the emphasis on the similarity of numerous essential clustering phenomena arising in different branches of physics, chemistry, and biology. After the four ISACC meetings it has become clear that there is a need for an interdisciplinary conference covering a broad range of topics related to the Dynamics of Systems on a Nanoscale. Therefore in 2010 it was decided to expand upon this series of meetings with a new conference organized under the new title &apos;&apos;Dynamics of Systems on the Nanoscale&apos;&apos;, the DySoN Conference, since this title better reflects the interdisciplinary character of the earlier ISACC meetings embracing all the topics of interest under a common theme. The first DySoN Conference took place in Rome, Italy in 2010. The fifth ISACC symposium will be again a

  4. Training activities at FSUE &apos;RADON&apos; and Lomonosov&apos;s Moscow state university under practical arrangements with IAEA

    International Nuclear Information System (INIS)

    Batyukhnova, O.G.; Karlina, O.K.; Neveykin, P.P.; Kalmykov, S.N.; Ojovan, M.I.

    2013-01-01

    The International Education Training Centre (IETC) at Moscow Federal State Unitary Enterprise (FSUE) &apos;Radon&apos;, in co-operation with the International Atomic Energy Agency (IAEA), has developed expertise and provided training to waste management personnel for the last 15 years. Since 1997, the educational system of the enterprise with the support of the IAEA has acquired an international character: more than 470 experts from 35 countries - IAEA Member States completed the professional development. Training is conducted at various thematic courses or fellowships for individual programs and seminars on IAEA technical projects. In June 2008 a direct agreement (Practical Arrangements) has been signed between FSUE &apos;Radon&apos; and the IAEA on cooperation in the field of development of new technologies, expert&apos;s advice to IAEA Member States, and, in particular, the training of personnel in the field of radioactive waste management (RWM), which opens up new perspectives for fruitful cooperation of industry professionals. A similar agreement - Practical Arrangements - has been signed between Lomonosov&apos;s MSU and the IAEA in 2012. In October 2012 a new IAEA two-weeks training course started at Lomonosov&apos;s MSU and FSUE &apos;Radon&apos; in the framework of the Practical Agreements signed. Pre-disposal management of waste was the main topic of the courses. The paper summarizes the current experience of the FSUE &apos;Radon&apos; in the organization and implementation of the IAEA sponsored training and others events and outlines some of strategic educational elements, which IETC will continue to pursue in the coming years. (authors)

  5. Development of complex simulation suite &apos;VEB&apos; and application area expansion - 15326

    International Nuclear Information System (INIS)

    Obraztsov, E.; Kapista, D.; Kremnev, I.; Korokhov, T.; Kukhtevich, V.; Bezlepkin, V.

    2015-01-01

    Complex simulation suite &apos;Virtual Unit of NPP&apos; (CSS &apos;VEB&apos;) is a set of connected software tools and computer codes that allow the simulation of various physical processes occurring in a power nuclear reactor (initially VVER - pressurized water reactor). A coupled computational model developed by means of CSS &apos;VEB&apos; is based on a specific design and called an NPP Virtual Power Unit (VPU). And in November 2012 a pilot version of the Leningrad NPP-2 VPU (NPP-2006 design with water-cooled power reactor) successfully passed acceptance tests. The paper presents further development of CSS &apos;VEB&apos; and application area expansion both on new tasks such as VPU calculations for the Probability Safety Analysis (PSA) and all modeling of other NPP types, like sodium-cooled reactor (that means a possibility to create a VPU not only for NPP with PWR). In the first part of this paper we will recall the basic idea and concept of CSS &apos;VEB&apos; and VPU. Then we will describe the main components of CSS &apos;VEB&apos; and their improvements. In the last part we will briefly describe the broadening of VPU uses

  6. J/{psi} production from Z&apos;&apos;0 decays at LEP energies; Produccion de J/{psi} en desintegraciones del Z&apos;&apos;0 a las energias de LEP I

    Energy Technology Data Exchange (ETDEWEB)

    Fernandez Alvarez, D.

    1993-07-01

    Study of J/{psi} production from the data recorded during 1991 with the L3 detector. The J/{psi} is identified by its decay J/{psi} - {mu}&apos;'+{mu}'&apos;- in the invariant mass spectrum of two muons. With our analysis results we have calculated the branching ratios Br(Z&apos;&apos;0 -J/{psi} + X) = (3.4 +- 0.7 (statistic)+- 0.2 (systematic)) x 10{sup 3} and Br(b-> J/{psi}+ X) = (1.20 +- 0.25 (statistic) +0.15 (systematic))%. (Author) 12 refs.

  7. An alternative realization of &apos;t Hooft&apos;s quantum determinism

    Energy Technology Data Exchange (ETDEWEB)

    Sadiq, M., E-mail: sadiq@qau.edu.p [Department of Physics, Quaid-i-Azam University, Islamabad 45320 (Pakistan); Ghafoor, F. [Centre for Quantum Physics, COMSATS Institute of Information Technology, Islamabad (Pakistan)

    2010-11-15

    We present an alternative to &apos;t Hooft&apos;s mechanism relating a deterministic system to a 1D quantum oscillator. We argue that it is possible to map &apos;t Hooft&apos;s ontological space onto an irreducible representation of a 2D isotropic oscillator. A direct group contraction procedure can then be applied to achieve the correspondence.

  8. Targeted In Situ Gene Correction of Dysfunctional APOE Alleles to Produce Atheroprotective Plasma ApoE3 Protein

    Directory of Open Access Journals (Sweden)

    Ioannis Papaioannou

    2012-01-01

    Full Text Available Cardiovascular disease is the leading worldwide cause of death. Apolipoprotein E (ApoE is a 34-kDa circulating glycoprotein, secreted by the liver and macrophages with pleiotropic antiatherogenic functions and hence a candidate to treat hypercholesterolaemia and atherosclerosis. Here, we describe atheroprotective properties of ApoE, though also potential proatherogenic actions, and the prevalence of dysfunctional isoforms, outline conventional gene transfer strategies, and then focus on gene correction therapeutics that can repair defective APOE alleles. In particular, we discuss the possibility and potential benefit of applying in combination two technical advances to repair aberrant APOE genes: (i an engineered endonuclease to introduce a double-strand break (DSB in exon 4, which contains the common, but dysfunctional, ε2 and ε4 alleles; (ii an efficient and selectable template for homologous recombination (HR repair, namely, an adeno-associated viral (AAV vector, which harbours wild-type APOE sequence. This technology is applicable ex vivo, for example to target haematopoietic or induced pluripotent stem cells, and also for in vivo hepatic gene targeting. It is to be hoped that such emerging technology will eventually translate to patient therapy to reduce CVD risk.

  9. Stressors at modern workplaces. &apos;'Technical-stres'&apos;-investigations in power plants; Stressoren an modernen Arbeitsplaetzen. Untersuchungen zum &apos;Technikstress&apos; in Kraftwerken

    Energy Technology Data Exchange (ETDEWEB)

    Hoppe, Annette; Binkowski, Sven [Brandenburgische Technische Univ. Cottbus (DE). Lehrgebiet Arbeitswissenschaft/Arbeitspsycholgoie (AWIP); Haake, Dietmar [Vattenfall Europe Generation AG und Co. KG, Cottbus (Germany). Elektro- und Leittechnik

    2008-07-01

    The status analyses of power plant control rooms from the viewpoint of ergonomics and psychology is focussing on scientific analyses of stressors at highly complicated work places in order to gain further knowledge on the issue of &apos;technology-induced stress&apos; and to a practical assessment of work places for the estimation of stresses. A guideline is to be developed supporting design of modern control rooms. (orig.)

  10. Accreting planets as dust dams in &apos;transition&apos; disks

    International Nuclear Information System (INIS)

    Owen, James E.

    2014-01-01

    We investigate under what circumstances an embedded planet in a protoplanetary disk may sculpt the dust distribution such that it observationally presents as a &apos;transition&apos; disk. We concern ourselves with &apos;transition&apos; disks that have large holes (≳ 10 AU) and high accretion rates (∼10 –9 -10 –8 M ☉ yr –1 ), particularly, those disks which photoevaporative models struggle to explain. Adopting the observed accretion rates in &apos;transition&apos; disks, we find that the accretion luminosity from the forming planet is significant, and can dominate over the stellar luminosity at the gap edge. This planetary accretion luminosity can apply a significant radiation pressure to small (s ≲ 1 μm) dust particles provided they are suitably decoupled from the gas. Secular evolution calculations that account for the evolution of the gas and dust components in a disk with an embedded, accreting planet, show that only with the addition of the radiation pressure can we explain the full observed characteristics of a &apos;transition&apos; disk (NIR dip in the spectral energy distribution (SED), millimeter cavity, and high accretion rate). At suitably high planet masses (≳ 3-4 M J ), radiation pressure from the accreting planet is able to hold back the small dust particles, producing a heavily dust-depleted inner disk that is optically thin to infrared radiation. The planet-disk system will present as a &apos;transition&apos; disk with a dip in the SED only when the planet mass and planetary accretion rate are high enough. At other times, it will present as a disk with a primordial SED, but with a cavity in the millimeter, as observed in a handful of protoplanetary disks.

  11. Hadronic distributions and correlations at &apos;small x&apos; in quantum chromodynamics; Distributions et correlations hadroniques en chromodynamique quantique dans l&apos;approximation des &apos;petit X&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Perez Ramos, R

    2006-09-15

    We exactly calculate the double and simple inclusive transverse momentum (kt) distributions and the 2-particle momentum correlations inside high energy hadronic jets at the Modified Leading Logarithmic Approximation (MLLA) of Quantum Chromodynamics. We first obtain the exact solution of the evolution equations at &apos;small x&apos;, which we calculate at the so called &apos;limiting spectrum&apos;. We then generalize this approximation by performing the steepest descent evaluation. Our predictions are in good agreement with data from Tevatron and improve those which have been obtained in the past. The comparison with forthcoming data (Tevatron, LHC) will further test the hypothesis of Local Hadron Parton Duality, and the eventual need to incorporate next-MLLA corrections. (authors)

  12. &apos;Focal thyroid inferno&apos; on color Doppler ultrasonography: A specific feature of focal Hashimoto&apos;s thyroiditis

    Energy Technology Data Exchange (ETDEWEB)

    Fu, Xianshui, E-mail: fuxs1968@163.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Guo, Limei, E-mail: guolimei@bjmu.edu.cn [Department of Pathology, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Zhang, Huabin, E-mail: huabinzhang@bjmu.edu.cn [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Ran, Weiqiang, E-mail: ranwq-sina@vip.sina.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Fu, Peng, E-mail: fupeng01@gmail.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Li, Zhiqiang, E-mail: lizhq126@126.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Chen, Wen, E-mail: wendy7989@sina.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Jiang, Ling, E-mail: papayaling@yahoo.com.cn [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Wang, Jinrui, E-mail: jinrui_wang@sina.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China); Jia, Jianwen, E-mail: drjia88@sohu.com [Department of Ultrasound, Peking University Third Hospital, 49 Huayuanbeilu Road, Beijing 100191 (China)

    2012-11-15

    Purpose: To evaluate color-Doppler features predictive of focal Hashimoto&apos;s thyroiditis. Materials and methods: A total of 521 patients with 561 thyroid nodules that underwent surgeries or gun biopsies were included in this study. These nodules were divided into three groups: focal Hashimoto&apos;s thyroiditis (104 nodules in 101 patients), benignity other than focal Hashimoto&apos;s thyroiditis (73 nodules in 70 patients), and malignancy (358 nodules in 350 patients). On color Doppler sonography, four vascularity types were determined as: hypovascularity, marked internal flow, marked peripheral flow and focal thyroid inferno. The {chi}{sup 2} test was performed to seek the potential vascularity type with the predictive ability of certain thyroid pathology. Furthermore, the gray-scale features of each nodule were also studied. Results: The vascularity type I (hypovascularity) was more often seen in focal Hashimoto&apos;s thyroiditis than other benignity and malignancy (46% vs. 20.5% and 19%). While the type II (marked internal flow) showed the opposite tendency (26.9% [focal Hashimoto&apos;s thyroiditis] vs. 45.2% [other benignity] and 52.8% [malignancy]). However, type III (marked peripheral flow) was unable to predict any thyroid pathology. Importantly, type IV (focal thyroid inferno) was exclusive to focal Hashimoto&apos;s thyroiditis. All 8 type IV nodules appeared to be solid, hypoechoic, and well-defined. Using &apos;focal thyroid inferno&apos; as an indicator of FHT, the diagnostic sensitivity and specificity were 7.7% and 100% respectively. Conclusions: The vascularity type of &apos;focal thyroid inferno&apos; is specific for focal Hashimoto thyroiditis. Recognition of this particular feature may avoid unnecessary interventional procedures for some solid hypoechoic thyroid nodules suspicious of malignancy.

  13. Uso do acamprosato no tratamento do zumbido: um estudo duplo-cego Tinnitus treatment with acamprosate: double-blind study

    Directory of Open Access Journals (Sweden)

    Andréia A. Azevedo

    2005-10-01

    Full Text Available O tratamento do zumbido é, ainda nos dias de hoje, um grande desafio para os otorrinolaringologistas. Várias lacunas persistem em sua fisiopatologia, tendo como resultado vários tipos de tratamento, com resultados muito irregulares. O acamprosato é uma droga utilizada no tratamento do alcoolismo, devido à sua ação reguladora da transmissão glutamatérgica e GABA-érgica, nunca tendo sido empregado no tratamento do zumbido. OBJETIVO: Avaliar a segurança e eficácia do uso do acamprosato, no tratamento do zumbido de causa neurossensorial. FORMA DE ESTUDO: ensaio clinico randomizado. MATERIAL E MÉTODO: 50 pacientes com zumbido de causa neurossensorial foram divididos em 2 grupos, 25 recebendo acamprosato e 25 placebo por 3 meses, em um estudo prospectivo duplo-cego, sendo analisados os efeitos terapêuticos e efeitos colaterais, de acordo com escala (nota de 1 a 10, atribuída pelo próprio paciente. RESULTADOS: Foi observado algum grau de melhora sintomatológica em 86,9% dos pacientes, sendo que em 47,8% dos casos observamos melhora superior a 50%, dados estatisticamente significativos em relação ao placebo. A incidência de efeitos colaterais encontrada foi baixa (12% e de intensidade leve, com boa tolerabilidade geral. CONCLUSÃO: O acamprosato, medicação utilizada no tratamento do alcoolismo, é eficaz e seguro para o tratamento do zumbido de causa neurossensorial, com percentual de melhora superior à maioria das medicações utilizadas para o tratamento do zumbido, constituindo uma excelente alternativa terapêutica.Nowadays, the treatment of tinnitus is still a great challenge for the otolaryngologists. Many facts remain unknown in its pathophysiology, leading to many different therapies, with irregular results. Acamprosate is a drug used in alcoholism treatment, due to its regulating effects in glutamatergic and GABA neurotransmission, and has never been used before in the treatment of tinnitus AIM: To evaluate efficacy and

  14. Imunonutrição e o tratamento do câncer = Immunonutrition and the cancer treatment

    Directory of Open Access Journals (Sweden)

    Oliveira, Helena Simões Dutra de

    2010-01-01

    Full Text Available Introdução: O binômio dieta e nutrição tem relação com causas e consequências do câncer. O estado nutricional é afetado diretamente tanto pelo tumor, quanto pelo tratamento administrado, exigindo manejo especial. Quando há depleção do estado nutricional, associa-se diminuição da função imune, o que favorece o avanço da doença. Para isso a imunonutrição poderia colaborar com a diminuição da taxa de infecções e do tempo de hospitalização no tratamento de pacientes com câncer. Objetivo: Revisar o papel da imunonutrição na melhora da resposta ao tratamento do câncer. Materiais e Métodos: Realizou-se estudo exploratório do tipo revisão bibliográfica a partir das bases de dados PubMed e LILACS, datados a partir de 1998, com os termos de indexação: imunomoduladores, câncer, terapia nutricional. Foram incluídas obras bibliográficas do tema em questão e outros artigos de relevância. Resultados: Foi realizada a revisão com sete estudos. Foram incluídos nesta revisão cinco capítulos de obras bibliográficas e outros três artigos de relevância do assunto. Os resultados foram organizados em uma categoria e três temas: imunonutrição no tratamento ao câncer, abrangendo conceito e características, tempo de administração de dietas imunomoduladoras e as neoplasias nas quais imunonutrição está mais envolvida. Conclusões: Poucas pesquisas com resultados significativos são encontradas quando comparadas a dietas-padrão, não sendo possível afirmar com segurança sobre os benefícios da imunonutrição no tratamento dos pacientes oncológicos em relação ao tempo de administração de fórmulas enriquecidas com esses imunomoduladores. Contudo, os benefícios relacionados a diminuição da taxa de infecções e ao tempo de hospitalização estão associados ao tipo de tratamento cirúrgico do câncer

  15. LXR agonist increases apoE secretion from HepG2 spheroid, together with an increased production of VLDL and apoE-rich large HDL

    Directory of Open Access Journals (Sweden)

    Koike Kazuhiko

    2011-08-01

    Full Text Available Abstract Background The physiological regulation of hepatic apoE gene has not been clarified, although the expression of apoE in adipocytes and macrophages has been known to be regulated by LXR. Methods and Results We investigated the effect of TO901317, a LXR agonist, on hepatic apoE production utilizing HepG2 cells cultured in spheroid form, known to be more differentiated than HepG2 cells in monolayer culture. Spheroid HepG2 cells were prepared in alginate-beads. The secretions of albumin, apoE and apoA-I from spheroid HepG2 cells were significantly increased compared to those from monolayer HepG2 cells, and these increases were accompanied by increased mRNA levels of apoE and apoA-I. Several nuclear receptors including LXRα also became abundant in nuclear fractions in spheroid HepG2 cells. Treatment with TO901317 significantly increased apoE protein secretion from spheroid HepG2 cells, which was also associated with the increased expression of apoE mRNA. Separation of the media with FPLC revealed that the production of apoE-rich large HDL particles were enhanced even at low concentration of TO901317, and at higher concentration of TO901317, production of VLDL particles increased as well. Conclusions LXR activation enhanced the expression of hepatic apoE, together with the alteration of lipoprotein particles produced from the differentiated hepatocyte-derived cells. HepG2 spheroids might serve as a good model of well-differentiated human hepatocytes for future investigations of hepatic lipid metabolism.

  16. Safety requirements expected to the prototype fast breeder reactor &apos;Monju&apos;

    International Nuclear Information System (INIS)

    2014-11-01

    In July 2013, Nuclear Regulation Authority (NRA) has enforced new regulatory requirements in consideration of severe accidents for the commercial light water reactors (LWR) and also prototype power generation reactors such as the sodium-cooled fast reactors (SFR) of &apos;Monju&apos; based on TEPCO Fukushima Daiichi nuclear power plant accident (hereinafter referred to as &apos;1F accident&apos;) occurred in March 2011. Although the regulatory requirements for SFR will be revised by NRA with consideration for public comments, Japan Atomic Energy Agency (JAEA) set up &apos;Advisory Committee on Monju Safety Requirements&apos; consisting of fast breeder reactor (FBR) and safety assessment experts in order to establish original safety requirements expected to the prototype FBR &apos;Monju&apos; considering severe accidents with knowledge from JAEA as well as scientific and technical insights from the experts. This report summarizes the safety requirements expected to Monju discussed by the committee. (author)

  17. Those who &apos;Cry Wolf&apos; about nuclear safety damage their own credibility

    Energy Technology Data Exchange (ETDEWEB)

    Shepherd, John [nuclear 24, Redditch (United Kingdom)

    2016-06-15

    Do you recall the fable of the boy who cried wolf? I was reminded of this following the latest call by Germany&apos;s Federal Environment Minister, Barbara Hendricks, for Belgium to take two of its nuclear reactors off the grid, citing &apos;'questions'&apos; about the units&apos; safety. Those in positions of power and influence in one country should take care to be as responsible in their dealings with their neighbours as they are in handling domestic matters of state. Those who see &apos;danger&apos; where there is none are not being good neighbours. They are generating fear and alarm without good cause and should mind their own business.

  18. First forum &apos;'BISE'&apos; for: the intelligent energy in the municipalities and the new member states, of candidate countries and western Balkans; Premier forum &apos;'BISE'&apos; pour: l&apos;energie intelligente dans les minicipalites des nouveaux etats membres, des pays candidats et des Balkans occidentaux

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2004-07-01

    The european commission and the european association of municipalities (Energie Cites) established a permanent &apos;&apos;Intelligent Energy Forum of European Municipalities&apos;&apos; (named BISE Forum) as form of periodical information exchange between municipal associations and other potential partners in Europe. In the framework of the reduction of the sustainable energy gap between the Central and Eastern European Countries and the most advanced energy-efficient EU 15 countries, the aim of this forum is to promote the creation of national energy cities networks, to integrate the initiatives and networks at an European scale and to promote the idea of an European Emergency Plan in order to improve energy efficiency in Eastern European Countries as quickly as possible. This document presents the proceedings and a selection of cases studies linked to the first BISE Forum. (A.L.B.)

  19. IPSN activity report 1999; Rapport d&apos;activite de l&apos;IPSN 1999

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    1999-07-01

    The &apos;&apos;Institut de Protection et de Surete Nucleaire&apos;&apos; (IPSN), carries out researches and expert studies needed to manage nuclear risks and their consequences on people and environment. These activities cover the installation safety, the radioactive matter transport, the public health and environmental control, the nuclear matters safety and control and the crisis situation management. The IPSN have got also a mission of public information and participates to international actions in the domain of scientific researches or expert&apos;s report. This annual report presents the highlights of the year 1999, information on staff, budgets and geographical situation. Then technical and scientific papers gathers the activities of the year covered by the IPSN: the &apos;&apos;Free Tribune&apos;&apos;, installations and radioactive wastes safety, crisis and nuclear matter management, public health and environment control, international cooperation. (A.L.B.)

  20. Analysis of proposed eco-design requirements for boilers and water heaters. Paper within the framwork of the &apos;&apos;Material Efficiency and Resource Conservation&apos;&apos; (MaRess) Project - Task 14

    Energy Technology Data Exchange (ETDEWEB)

    Barthel, Klaus; Franke, Moritz [Wuppertal Institute for Climate, Environment and Energy, Wuppertal (Germany)

    2009-12-15

    In 2005, the European Union released the EuP Directive focusing on ecodesign requirements for energy-using products (2005/32/EC: EU Parliament and Council of the EU 2005). This directive, also called Ecodesign Directive, is a framework directive establishing a structure in which so-called implementing measures define specific requirements for placing products on the market and/or putting them into service within the internal European market. These requirements can be environmental performance standards (e.g. minimum energy efficiency or emission standards) and labelling or information requirements. Some existing European directives are already declared as being implementing measures of the Ecodesign Directive. Additionally, new implementing measures have been and will further be developed. Product-specific preparatory studies on behalf of the European Commission provide the basis for this. The preparatory studies for boilers (Lot 1) and water heaters (Lot 2) have been conducted from February 2006 to October 2007 by Van Holsteijn en Kemna (VHK). Based on the preparatory studies, the EU Commission has released several working documents (WD) on possible ecodesign requirements for boilers and water heaters at the beginning of 2008. Following these documents, boilers and water heaters comprise gas-fired, oil-fired and electric central heating (CH) (combi-) boilers / dedicated water heaters in combination with capturing solar thermal energy or ambient heat1. The requirements contain basically energy labelling measures, minimum efficiency performance standards and limits on NOx emissions. An &apos;&apos;Ecoboiler Model&apos;&apos; resp. an &apos;&apos;Eco Hot Water Model&apos;&apos; has been elaborated within the preparatory studies. These models are a crucial part of the requirements and allow for calculation of the efficiencies of boilers and water heaters. Since the models have a high degree of complexity, the Federal Environment Agency (UBA) has asked Wuppertal

  1. Results of the project &apos;combustion modelling&apos; (BKM II); Ergebnisse des Projekts &apos;Brennkammermodellierung&apos; (BKM II)

    Energy Technology Data Exchange (ETDEWEB)

    Noll, B.; Rachner, M.; Frank, P.; Schmitz, G.; Geigle, K.P.; Meier, W.; Schuetz, H.; Aigner, M. [DLR Deutsches Zentrum fuer Luft- und Raumfahrt e.V., Stuttgart (Germany). Inst. fuer Verbrennungstechnik; Kessler, R. [DLR Deutsches Zentrum fuer Luft- und Raumfahrt e.V., Goettingen (Germany). Inst. fuer Aerodynamik und Stroemungstechnik; Lehmann, B. [DLR Deutsches Zentrum fuer Luft- und Raumfahrt e.V., Koeln (Germany). Inst. fuer Antriebstechnik; Forkert, T. [DLR Deutsches Zentrum fuer Luft- und Raumfahrt e.V., Koeln (Germany). Simulation und Softwaretechnik

    2002-07-01

    In the year 1996 the spheres of competence of several DLR-Institutes working in the areas of fluid dynamics, reaction kinetics, combustion, numerical methods and laser measuring techniques have been brought together while contributing to the internal DLR project &apos;combustion chamber modelling (BKM)&apos;, in order to proceed with the computational simulation of combustion processes in combustion chambers of gas turbines. The main issue was the development of a research code for numerical simulation of fluid flow in real combustion chambers. Here the development of computational models of physical and chemical processes was emphasized, among other processes the formation of soot was treated. Moreover, a worldwide outstanding database of measured data for the purpose of code validation has been created within the framework of the BKM project using the laboratory facilities of the DLR, which are in Germany unique for the experimental investigation of the various processes in combustion chambers of gas turbines. The project BKM is part of the specific DLR-programme &apos;energy&apos;. With the successful completion of the first phase of the project in 1998, a second project phase of three years (BKM II) has been launched at the beginning of 1999. Here the work of the first phase continued and new topics were tackled. The second phase of the project was partly founded by the DLR-programme &apos;aeronautics&apos;. (orig.) [German] Im Jahr 1996 wurden die Faehigkeiten mehrerer DLR-Institute auf den Gebieten Stroemungsmechanik, Reaktionskinetik, Verbrennung sowie Numerische Verfahren und Laser-Messverfahren in dem DLR-internen Projekt &apos;Brennkammermodellierung&apos; (BKM) zusammengefuehrt, um die rechnerische Simulation der Verbrennungsvorgaenge in Gasturbinen-Brennkammern voranzutreiben. Dabei war die Entwicklung eines Forschungscodes zur numerischen Simulation von realen Brennkammerstroemungen das vorrangige Ziel der Arbeiten. Ein besonderes Schwergewicht lag

  2. Village Power &apos;98

    Energy Technology Data Exchange (ETDEWEB)

    Cardinal, Julie; Flowers, Larry; Siegel, Judy; Taylor, Roger; Weingart, Jerome

    1999-03-24

    This is the fifth Village Power workshop sponsored by NREL. We have held these meetings every year since 1993, to focus, challenge, and provide a forum for interaction among practitioners working in the field of using renewable energy technologies as an economically viable pathway to electrification of rural populations throughout the world. Starting with a small group of 30 colleagues in 1993, this &apos;'workshop'&apos; has doubled in size every year. When the NREL staff was planning for this meeting, they were hoping for something around 400 participants. We are now looking at over 500, and we apologize for the somewhat cramped accommodations. This overwhelming response, however, shows that the use of renewable energy to solve some of the world&apos;s serious problems is coming of age. This meeting, this &apos;'conference'&apos; (it&apos;s clearly no longer a workshop) marks a transition. A transition from the viewpoint that renewables are, and forever will be a technology of the future; to the reality that renewables have come of age. We have technologies available today, at today&apos;s prices, that can make a substantive contribution to the pressing needs of environmentally sustainable development in the world. This is a collection of all the papers presented at the Village Power &apos;98 conference.

  3. Developing Preschool Teachers&apos; Knowledge of Students&apos; Number Conceptions

    Science.gov (United States)

    Tsamir, Pessia; Tirosh, Dina; Levenson, Esther; Tabach, Michal; Barkai, Ruthi

    2014-01-01

    This article describes a study that investigates preschool teachers&apos; knowledge of their young students&apos; number conceptions and the teachers&apos; related self-efficacy beliefs. It also presents and illustrates elements of a professional development program designed explicitly to promote this knowledge among preschool teachers. Results…

  4. Avaliação de pacientes pós-tratamento com terlipressina

    Directory of Open Access Journals (Sweden)

    Rafael Dornelles Carrasco

    2013-05-01

    Full Text Available Introdução: Sangramento de varizes esofágicas e síndrome hepatorrenal são complicações com altas taxas de morbidade e são comuns em pacientes cirróticos. A terlipressina é um fármaco com atividade vasoconstritora utilizado para melhorar as condições clínicas dessas complicações tanto no pré- quanto no pós-operatório. Objetivo: Descrever o perfil dos pacientes submetidos ao tratamento com terlipressina, bem como avaliar a situação clínica após o tratamento e seu desfecho. Método: Estudo transversal, descritivo, com análise de prontuários eletrônicos de pacientes que receberam terlipressina em um hospital do sul do Brasil. Os dados analisados foram idade, sexo, período de internação, quantidade de doses administradas ao paciente durante o tratamento com terlipressina, duração do tratamento, causa da internação hospitalar, indicação da terlipressina, se seu uso foi conforme o Protocolo Assistencial de Hemorragia Digestiva (no caso de varizes esofágicas e condição do paciente na alta. Resultados: Foram avaliados 37 prontuários. Observou-se que 18 (48,7% pacientes tinham idade superior a 60 anos; 25 (67,6% eram do sexo masculino; para 18 (48,7% o tempo de internação ficou em torno de 7 dias; 14 (37,8% foram internados por sangramento digestivo, sendo que, desses, 11 (78,6% não puderam seguir as condutas do Protocolo Assistencial de Hemorragia Digestiva; 17 (45,9% receberam mais de 12 doses de terlipressina, que, para 19 (51,3%, durou até dois dias. Conclusão: Considerando a gravidade dos pacientes, os resultados foram concordantes com os dados disponíveis na literatura. O uso de terlipressina justifica-se por melhorar as condições clínicas dos pacientes e por aumentar a sobrevida em casos mais críticos. Palavras-chave: Hemorragia gastrointestinal; varizes esofágicas e gástricas; síndrome hepatorrenal

  5. Tratamento cirúrgico da retinopatia diabética

    Directory of Open Access Journals (Sweden)

    Nelson Alexandre Sabrosa

    2013-06-01

    Full Text Available A retinopatia diabética é a causa mais frequente de cegueira na população ativa nos países desenvolvidos. A prevalência da retinopatia diabética aumenta com a duração da diabetes, e praticamente 100% dos pacientes com diabetes tipo I (DM I e mais do que 60% dos pacientes com o tipo II (DM II apresentarão algum sinal de retinopatia após 20 anos. Além de um controle sistêmico rigoroso dos níveis glicêmicos, lipídicos, colesterol e da pressão arterial, o exame oftalmológico de rotina, com a identificação precoce da retinopatia diabética, podem detectar anormalidades em estágios primários, o que possibilita o tratamento ainda na fase inicial do problema; o uso adequado da fotocoagulação e a utilização da terapia antiangiogênica pode reduzir o número de pacientes com hemorragia vítrea ou descolamento tracional da retina. Infelizmente, em vários pacientes, a retinopatia progride mesmo com as melhores condutas tomadas pelo paciente e pelo oftalmologista, embora vários olhos podem se beneficiar com o tratamento cirúrgico, a vitrectomia posterior via pars plana. Esta revisão apresenta as indicações atuais para cirurgia vitreorretiniana em pacientes portadores de retinopatia diabética proliferativa.

  6. &apos;Finnova Development Group&apos;. Comb Configurated Costumer-close Network Installations with Underground Service Boxes; &apos;Finnova&apos; Innovativ Montage och Systemloesning foer Fjaerrvaermeanslutning av Villaomraade. Huvudloesning &apos;Kamfoerlaeggning med Serviceskaap&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Gudmundson, Tommy [AaF-Process AB, Stockholm (SE)] (and others)

    2006-07-15

    In this report a completely new approach to the distribution of District Heating Services is presented. The general idea of the solution, here presented under the name Comb Configurated Costumer close Network Installations with Underground Service Boxes (in the following referred to as Finnova AF), was given birth during a very early stage of the working process of the FDG. The goal for our &apos;Vaermegles&apos;- project (&apos;Vaermegles&apos; means for a residential area to have a low heat demand) is to present a technical solution that implies a substantial cost reduction for establishing DH in such low heat demand residential areas, when compared with what is recognized as to-day applied &apos;best technology&apos;. The aim point was, in the cost level of 2003/2004, VAT not included, a total investment sum of SEK 50,000 (about 7,000 USD). Using flexible piping, delivered to the site as coils of 100 m of pipes each, installed according to the Comb configuration principle, no joints installed directly in the ground are needed. The number of street crossings is strongly reduced, as compared with today&apos;s practice. The total of the joint assembly work takes place inside underground service boxes, situated at the building site boundaries. In this way the continuity of the building process is strongly improved. The stages of operation: digging, installing of pipes, backfilling and arranging of service boxes will take place in shortest possible time. As a prototype, the so called service box (e g a service and connection box, let us call it an &apos;S/C&apos; box) is square, made of concrete and will be installed with its roof 4-8 inches above ground. Inside the box, a fully equipped DH &apos;substation&apos;, designed as an easily replaceable cassette. In the prototype the closing cap is made from a galvanised steel sheet. The same box and cassette designs can be used for almost all single family houses with a heat demand not exceeding 10 kW. This gives a

  7. Pós-tratamento de efluente de reator anaeróbio em lagoa com lemna

    OpenAIRE

    Lubarino, Elizângela Alves

    2013-01-01

    A ausência de tratamento e a disposição inadequada de efluentes domésticos contribuem para a deterioração de corpos receptores. Porém, dentre as alternativas propostas para o pós-tratamento de águas residuárias estão as lagoas de lemnas. Essas lagoas são capazes de captar nutrientes do esgoto com eficiência, bem como, reduzir uma grande quantidade de sólidos em suspensão. Também atuam na inibição de algas, e geram biomassa rica em proteínas que tem utilidades como ração animal e adubo. Esta p...

  8. Tratamento Videolaparoscópico de Endometriomas Ovarianos

    Directory of Open Access Journals (Sweden)

    Lopez Adriana C.S.

    2000-01-01

    Full Text Available Objetivo: avaliar os resultados do tratamento videolaparoscópico de 32 pacientes com endometrioma ovariano. Métodos: estudo retrospectivo que incluiu trinta e duas pacientes encaminhadas ao setor de Endoscopia Ginecológica do Serviço de Ginecologia e Obstetrícia do Hospital do Servidor Público Estadual "Francisco Morato de Oliveira" - São Paulo, as quais tinham diagnóstico clínico e ultra-sonográfico de endometrioma ovariano e foram tratadas por videolaparoscopia. Onze pacientes com endometriomas com diâmetro menor que 3 cm foram submetidas à drenagem do endometrioma e exérese da cápsula na primeira laparoscopia. Vinte e uma pacientes com endometriomas com diâmetros maior que 3 cm foram submetidas à drenagem do endometrioma e lavagem do cisto na primeira laparoscopia. A seguir, utilizaram análogo do GnRH por quatro meses (1 ampola mensal e então foram submetidas à segunda laparoscopia para retirada da cápsula do endometrioma. O exame histopatológico do material obtido na cirurgia foi realizado em todos os casos. Avaliou-se o resultado imediato do procedimento e a freqüência de recidivas. Resultados: não se registraram intercorrências cirúrgicas ou complicações pós-operatórias. Ocorreram três recidivas em um período de seis a doze meses, todas no grupo de 21 pacientes com endometriomas com o diâmetro maior que 3 cm. Conclusão: o tratamento videolaparoscópico dos endometriomas ovarianos com retirada da cápsula apresenta bons resultados e baixo índice de recidiva.

  9. Paracoccidioidomicose subaguda progressiva: tratamento de um doente com anfotericina B e nutrição parenteral

    Directory of Open Access Journals (Sweden)

    Paulo Camara Marques Pereira

    1985-10-01

    Full Text Available Os Autores descrevem um caso de paracoccidioidomicose subaguda progressiva, com quadro clínico sugestivo de síndrome de má absorção, em que o doente não se beneficiara apenas com o tratamento antifúngico convencional. Ao se introduzir como medida auxiliar a nutrição parenteral houve evidente melhora clínica e laboratorial. Desta maneira os Autores propõe o uso associado da nutrição parenteral no tratamento de doentes com esta forma clínica de paracoccidioidomicose.

  10. [Effect of Huanglian Jiedu Decoction on Monocyte Development in apoE Gene Knockout Mice].

    Science.gov (United States)

    Chen, Bing; Kong, Ya-xian; Ll, Yu-mei; Xue, Xin; Zhang, Jian-ping; Zeng, Hui; Hu, Jing- qing; Ma, Ya-luan

    2016-01-01

    To observe monocyte (Mo) development in wild type C57BL/6 mice and apoE gene knockout (apoE(-/-)) mice, and to evaluate the immuno-regulatory effect of Huanglian Jiedu Decoction (HJD) on peripheral Mo development in apoE(-/-) mice. Four, 8, 12, and 16 weeks old female C57BL/6 mice were set up as control groups of different ages, while 4, 8, 12, and 16 weeks old female apoE(-/-) mice were set up as hyperlipidemia groups of different ages. Four-week old female C57BL/6 mice were recruited as a blank group. Four-week old female apoE(-/-) mice were randomly divided into the control group, the Western medicine group, and the Chinese medicine group by paired comparison, 5 in each group. Equivalent clinical dose was administered to mice according to body weight. Mice in the Western medicine group were administered with Atrovastatin at the daily dose of 10 mg/kg by gastrogavage, while those in the Chinese medicine group were administered with HJD at the daily dose of 5 g/kg by gastrogavage. Body weight was detected each week. After 4 weeks blood lipids levels (such as TG, TC, LDL-C, and HDL-C), and the proportions of Mo and Ly6c(hi) were detected. Compared with 4-week-old homogenic mice, the proportion of Mo decreased in 16-week-old C57BL/6 mice (P < 0.05). Levels of TC and TG, and the proportion of Ly6c(hi) subtype increased, but the proportion of Mo de- creased in 8-week-old apoE(-/-) mice (P <0. 05). Levels of TC, TG, and LDL-C increased in 12-week-old apoE(-/-) mice (P < 0.05). Levels of TC, TG, LDL-C, and HDL-C increased in 16-week-old apoE(-/-) mice (P < 0.05, P < 0.01). Compared with 8-week-old homogenic mice, the proportion of Mo decreased in 16-week-old C57BL/6 mice (P < 0.05); levels of TC and LDL-C increased in 12-week-old apoE(-/-) mice (P < 0.05); levels of TC and HDL-C increased in 16-week-old apoE(-/-) mice (P < 0.05, P < 0.01). Compared with C57BL/6 mice of the same age, TC and TG increased, HDL-C decreased (P < 0.01) in 4-and 8-week-old apoE(-/-) mice (P

  11. Effects of nocturnal aircraft noise on sleep: results from the &apos;&apos;quiet air traffic&apos;&apos; project; Wirkungen des Nachtfluglaerms auf den Schlaf: Ergebnisse aus dem Projekt &apos;&apos;Leiser Flugverkehr&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Samel, A.; Basner, M.; Maass, H.; Mueller, U.; Quehl, J.; Wenzel, J. [Deutsches Zentrum fuer Luft- und Raumfahrt (DLR) in der Helmholtz-Gemeinschaft (HGF), Inst. fuer Luft- und Raumfahrtmedizin, Koeln (Germany)

    2005-07-01

    In 192 sleep-healthy subjects (18 to 65 y) effects of nocturnal aircraft noise on sleep, stress, performance and subjective factors were investigated in 2240 nights under laboratory and field conditions. In the sleep lab, 112 volunteers were subjected to aircraft noise events by varying numbers and noise levels during 9 nights within a period of 13 nights. 16 further subjects served as control group (i.e. without any noise). 64 subjects were studied in the vicinity of Cologne-Bonn airport during 9 nights. Polysomnographical and acoustical recordings, determination of excretion rates of stress hormones from night urines, performance tests and questionnaires were conducted during all days for the assessment of nocturnal aircraft noise effects. By simultaneous recording of electrophysiological and acoustical data the probability of noise induced awakenings was estimated. Performance and most of psychological parameters did not show significant dose-effect relationships, whereas annoyance did. Epinephrine and norepinephrine did not change under aircraft noise, cortisol did change only in the lab. In the lab, a comparison between all noisy nights and noise-free baseline nights exhibited a non-significant 2-min. reduction of sleep and a 4-min. decrease of slow-wave sleep. In the field, awakenings caused by aircraft noise were detected above a threshold of 33 dB(A) &apos;&apos;at the sleeper&apos;s ear&apos;&apos;. All effects were much less pronounced in the field than in the lab. For the first time, precise dose-effect curves between maximum aircraft noise event levels and electrophysiologically detectable awakenings, and a threshold were empirically established. The results of these studies broadens the knowledge on aircraft noise induced sleep disturbances and immediate consequences for the next day. (orig.)

  12. It&apos;s the system, stupid! The architecture, the services, the currencies, the sources and &apos;why hydrogen&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Scott, D.S. [International Association for Hydrogen Energy, Victoria, British Columbia (Canada)

    2009-07-01

    &apos;Full text:&apos; Drawing from Smelling Land: The Hydrogen Defense Against Climate Catastrophe, the talk will introduce a novel view of energy system architecture, to use as a platform from which to better appreciate where we were yesterday, are today and, with luck, will be tomorrow. We will introduce and explain the key concept of energy &apos;currencies&apos; - whose place in the energy system is seen from the figure below: Services - Services Technologies - Currencies - Transformer Technologies - Sources. The talk will review tragicomic Canadian examples of what happens when we forget the system, to focus only on its bits and piece. Many persist today. The discussion will explain why hydrogen systems are essential if we&apos;re to have a chance to escape climate catastrophe. Almost all today&apos;s proposals for deflecting climate disruption are, at best, bandaids. Any comprehensive solution must ultimately lead to zero CO{sub 2} emissions. That will require not just non-carbon energy sources but also non-carbon energy currencies. We already have the non-carbon currency electricity. But electricity can&apos;t fly airplanes, or push ships, and is a poor currency for road or rail. For these we&apos;ll need the non-carbon currency, hydrogen. Only hydrogen can allow the energy from non-carbon sources like hydraulic, nuclear, sunlight or wind, to fly airplanes - further, faster, safer and with larger payloads without the system emitting (in principle) a drop of CO{sub 2}. The synergies apparent with liquid-hydrogen fuelled aircraft exemplify the synergies of all hydrogen-fuelled transportation vehicles. On the way to this brilliant future, &apos;tether&apos; hydrogen must play a vital role harvesting Canada&apos;s heavy oil reserves while minimizing collateral CO{sub 2} emissions. Later, &apos;neat&apos; hydrogen systems will bring the brilliant future that will be the Hydrogen Age. The 20th century bequeathed us the wonders of the Electricity Age. The 21st

  13. It&apos;s the system, stupid! The architecture, the services, the currencies, the sources and &apos;why hydrogen&apos;

    International Nuclear Information System (INIS)

    Scott, D.S.

    2009-01-01

    &apos;Full text:&apos; Drawing from Smelling Land: The Hydrogen Defense Against Climate Catastrophe, the talk will introduce a novel view of energy system architecture, to use as a platform from which to better appreciate where we were yesterday, are today and, with luck, will be tomorrow. We will introduce and explain the key concept of energy &apos;currencies&apos; - whose place in the energy system is seen from the figure below: Services - Services Technologies - Currencies - Transformer Technologies - Sources. The talk will review tragicomic Canadian examples of what happens when we forget the system, to focus only on its bits and piece. Many persist today. The discussion will explain why hydrogen systems are essential if we&apos;re to have a chance to escape climate catastrophe. Almost all today&apos;s proposals for deflecting climate disruption are, at best, bandaids. Any comprehensive solution must ultimately lead to zero CO 2 emissions. That will require not just non-carbon energy sources but also non-carbon energy currencies. We already have the non-carbon currency electricity. But electricity can&apos;t fly airplanes, or push ships, and is a poor currency for road or rail. For these we&apos;ll need the non-carbon currency, hydrogen. Only hydrogen can allow the energy from non-carbon sources like hydraulic, nuclear, sunlight or wind, to fly airplanes - further, faster, safer and with larger payloads without the system emitting (in principle) a drop of CO 2 . The synergies apparent with liquid-hydrogen fuelled aircraft exemplify the synergies of all hydrogen-fuelled transportation vehicles. On the way to this brilliant future, &apos;tether&apos; hydrogen must play a vital role harvesting Canada&apos;s heavy oil reserves while minimizing collateral CO 2 emissions. Later, &apos;neat&apos; hydrogen systems will bring the brilliant future that will be the Hydrogen Age. The 20th century bequeathed us the wonders of the Electricity Age. The 21st century is filled

  14. Using the automized system &apos;'section'&apos; to forecast velocity sections using data on borehole velocity measurement and seismic field prospecting

    Energy Technology Data Exchange (ETDEWEB)

    Dorman, M.I.; Gein, F.F.; Zubairov, F.B.

    1981-01-01

    A system of automated processing of seismic data is examined which makes it possible to set up rate functions at arbitrary points of a seismic prospecting section or at points conciding with boreholes in which rate measurements have not been completed. The basis for the forecasting method is data on seismic well logging investigations, seismic prospecting and some indirect observations on sections. The bases of a procedure realizing a forecasting method are set forth, as are those requirements which satisfy the system as a whole. The results of using the &apos;'section'&apos; system in a terrestrial section of Western Siberia are set forth.

  15. Considerações sobre o tratamento das hemorragias subaracnóideas espontâneas

    Directory of Open Access Journals (Sweden)

    J. Armbrust-Figueikedo

    1952-09-01

    Full Text Available O tratamento das hemorragias subaracnóideas espontâneas é estudado pormenorizadamente. Com poucas exceções, êsses casos são devidos a rotura de um aneurisma intracraniano, situado em 72% dos casos na artéria carótida interna ou em um de seus ramos principais. A incidência e a etiologia dos aneurismas são discutidas. O aneurisma se deve a um imperfeito desenvolvimento das paredes vasculares, associado a uma lesão degenerativa. A sintomatologia está ausente, na grande maioria dos casos, até a rotura do aneurisma, quando o paciente perde a consciência, entra em choque, com sinais de comprometimento dos nervos cranianos ou dos centros superiores. A presença de sangue no líqüido cefalorraquídeo, com aumento da pressão, é achado diagnóstico. O prognóstico dos aneurismas é grave; 40% dos pacientes vêm a falecer com a primeira hemorragia; daqueles que resistem ao primeiro acidente, 30% virão a falecer no segundo, terceiro ou quarto episódios dentro de um período de 10 anos. O tratamento da fase aguda é conservador, com absoluto repouso no leito. Quando as condições o permitam, arteriografias devem ser obtidas para demons- tração do aneurisma. O tratamento cirúrgico deve então ser instituído, a técnica variando de acôrdo com a localização da lesão, condições da circulação colateral, possibilidade de acesso cirúrgico direto, etc. O tratamento indireto deve ser associado ao direto, sempre que possível; far-se-á, portanto, a oclusão de uma ou mais artérias no pescoço com subseqüente isolamento intracraniano do aneurisma. As diferentes técnicas cirúrgicas são discutidas. Nos casos tratados pelo método conservador a mortalidade é de 48% e nos casos tratados pela cirurgia, de 14%. Cinco casos de aneurismas intracranianos são apresentados com a finalidade única de ilustrar os problemas clínicos. Êsses casos demonstram os diferentes tipos de evolução clínica e refletem a gravidade do progn

  16. Energy efficiency ground-source energy system, Environmental Protection Law, article &apos;Heat and cold storage, value for money&apos;; Energierendement bodemenergiesysteem, Wet milieubeheer, artikel &apos;WKO, waar voor je geld&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Lambregts, E.G.M.; Teunissen, P.O.M.; Beukenhorst, E.

    2013-01-15

    Upscaling of ground-source energy systems can contribute to heat and cold storage systems and thus reduce CO2 emission for the Amsterdam municipality. Based on the results of the project &apos;Heat and cold storage; Value for money&apos; a proposal was made to the Dutch Ministry of Infrastructure and Environment to include a regulation &apos;energy efficiency heat and cold storage&apos; in the Environmental Protection Law [Dutch] In het kader van de CO2 doelstelling van Amsterdam om 40% CO2 te reduceren in 2025 t.o.v. van 1990 wordt de verdere opschaling van de techniek bodemenergiesysteem gezien als een techniek die in belangrijke mate kan bijdragen aan de pijler &apos;transitie duurzame warmte en koude&apos;. Op landelijk en gemeentelijk niveau werd gesignaleerd dat (open) bodemenergiesystemen in de exploitatiefase veelal onvoldoende functioneerden. In dit rapport wordt op basis van de resultaten van het project &apos;WKO, waar voor je geld&apos; een voorstel aan het Ministerie van I en M gedaan om een voorschrift &apos;energierendement wko&apos; op te nemen in het Activiteitenbesluit Wet milieubeheer.

  17. Bookshelf (John R. Huizenga, &apos;Cold Fusion: the Scientific Fiasco of the Century&apos;)

    International Nuclear Information System (INIS)

    Morrison, Douglas R.O.

    1994-01-01

    &apos;&apos;Cold fusion is dead, isn&apos;t it?&apos;&apos; is a question I am often asked. The reply is a strange one, &apos;&apos;Yes, scientifically it is dead, but not from a media point of view or from funding&apos;&apos; In 1989 two electrochemists, Martin Fleischmann and Stanley Pons, claimed sustained nuclear fusion had been achieved in a test-tube with a palladium cathode and deuterium, observing excess heat, neutrons and tritium. A series of encouraging confirmations and successively greater excess heat claims were seized on by the world&apos;s media. The US Government set up a panel of some 20 world-class scientists from several disciplines under John Huizenga, distinguished professor of Chemistry and Physics at the University of Rochester. They concluded that there was no present evidence for the discovery of a new nuclear process termed cold fusion. It might be thought that would end cold fusion, but for interesting reasons, it did not entirely. John Huizenga has written a book describing the curious claims and evidence for cold fusion and has given an excellent explanation of the science involved. This was published as a hardback book of 236 pages, telling the story up to the end of June 1990. Again one might think it was the end of the cold fusion story. Now he has written about what happened in the next two years in a paperback book which contains an epilogue of 51 pages. If you thought the first year was extraordinary, the next two years described in the new edition were even more incredible! In the main part of the book, the basic science is simply and clearly explained. The number of &apos;'miracles'&apos; required for each results or theory is described - a &apos;'miracle'&apos; is a gross violation of previous knowledge and experimental results such as energy conservation. Thus some theories are classified as &apos;&apos;triple miracles&apos;&apos;. It might be thought that people who claimed to have observed cold fusion

  18. Tratamentos pré-germinativos em sementes de duas espécies do gênero Poincianella

    Directory of Open Access Journals (Sweden)

    Elane Grazielle Borba de Sousa Ferreira

    Full Text Available Objetivou-se nesse trabalho avaliar o efeito de diferentes tratamentos pré- germinativos em sementes de Poincianella bracteosa e Poincianella pyramidalis. Foram testados os seguintes tratamentos: embebição em água por 24 horas; embebição em água a 80 ºC até atingir a temperatura ambiente; escarificação com lixa; escarificação com lixa seguida da embebição em água por 24 horas; escarificação química com ácido sulfúrico concentrado por 30 segundos, 1; 5 e 10 minutos e a testemunha. A avaliação do efeito dos tratamentos foi feita pelas variáveis: germinação, primeira contagem e índice de velocidade de germinação, comprimento da raiz principal e da parte aérea e a determinação da massa seca da raiz e da parte aérea das plântulas. Concluiu-se que as sementes de P. bracteosa e P. pyramidalis não apresentam dormência tegumentar.

  19. Werner Heisenberg. The language of the atoms. Life and work - a scientific biography - the &apos;&apos;joyous science&apos;&apos; (youth until Nobel price); Werner Heisenberg. Die Sprache der Atome. Leben und Wirken - Eine wissenschaftliche Biographie - Die &apos;&apos;froehliche Wissenschaft&apos;&apos; (Jugend bis Nobelpreis)

    Energy Technology Data Exchange (ETDEWEB)

    Rechenberg, Helmut [MPI fuer Physik, Muenchen (Germany). Werner-Heisenberg-Institut

    2010-07-01

    With his discovery that measuring values of complementary fundamental quantities in the microscopic world cannot by arbitrarily precisely determined cutted Werner Heisenberg the Gordian knot for the finishing of quantum theory developed by Planck, Einstein, and others and opened by this a new &apos;&apos;golden era&apos;&apos; in the physics of the 20th century. On the base of the documents from his life and work, i. e. deeds, letters and reports of contemporaries, as well as the published and unpublished essays, books, and articles of Heisenberg - also the later on found, publications or manuscripts mainly coming from the inheritance - resulted this systematic biography of Heisenberg. The author, the last doctoral candidate of Heisenberg relied furthermore on factual and personal knowledges, mainly own remembrances on his doctoral father and his teachers, colleagues, and students. Because of the interest of an authentical biography of the theoretical physicist Heisenberg the presentation of the mathematical approaches and the corresponding derivations could not completely be abandoned. This biography appeals by this both to a scientifically cultivated as a wider in science interested audience and covers the first phase of Heisenberg&apos;s life until his Nobel price 1933. [German] Mit seiner Entdeckung, dass sich Messwerte komplementaerer Groessen in der mikroskopischen Welt nicht beliebig genau bestimmen lassen, durchschnitt Werner Heisenberg den Gordischen Knoten zur Vollendung der von Planck, Einstein und anderen entwickelten Quantentheorie und eroeffnete damit ein neues &apos;&apos;goldenes Zeitalter&apos;&apos; in der Physik des 20. Jahrhunderts. Auf der Grundlage der Dokumente aus seinem Leben und Wirken, d.h. der Urkunden, Briefe und Berichte von Zeitzeugen sowie der publizierten und unpublizierten Abhandlungen, Buecher und Artikel Heisenbergs - auch der spaeter aufgefundenen, ueberwiegend aus dem Nachlass Heisenbergs stammenden Veroeffentlichungen oder

  20. Deep groundwater flow systems and their characterization in single-well settings by &apos;'push-pull'&apos; tracer tests

    International Nuclear Information System (INIS)

    Hebig-Schubert, Klaus

    2014-01-01

    This thesis demonstrates the growing importance of deep groundwater research and the increasing demand for the development of suitable single-well test methods. At the forefront of the research on groundwater in the deep underground, radioactive waste disposal in deep geological repositories, CO 2 storage, geothermal energy supply, and aquifer storage and recovery systems (ASR) are on the agenda. The developments of suitable methods for investigating these resources are a main target. Currently available methods show considerable limitations. Accordingly, comprehensive methods for the hydraulic and hydrochemical characterization of deeper aquifers with single-well access are needed. Therefore, the goal of this PhD thesis was to identify, test, and enhance potentially suitable single-well methods for characterization of groundwater flow and solute transport in such settings. For this, several Single-Well Injection-Withdrawal (&apos;'push-pull'&apos;) tracer tests were applied at the Hamasato field site (Horonobe, Japan) in a ∝100 m deep groundwater monitoring well. Aim was to characterize the impact of a dynamic saltwater-freshwater interface on a coastal aquifer. Based on the experiences of the first methodological test, a second field campaign was conducted. This campaign focused on a systematic evaluation of the push-pull tracer test method for the first time at all. The experiments focused on the investigation of the so-called &apos;'chaser'&apos; and its impact on the test results. The chaser is a specific part of many push-pull tracer tests setups. From these experiments, a specific test design for the investigation of the saltwater-freshwater interface in a single-well setting was developed. The application of this design on questions regarding different fluids within the same system, e.g. different mineralized fluids (saltwater-freshwater-interface, ASR) or temperatures (geothermal research), are promising future approaches for this

  1. Deep groundwater flow systems and their characterization in single-well settings by &apos;'push-pull'&apos; tracer tests

    Energy Technology Data Exchange (ETDEWEB)

    Hebig-Schubert, Klaus

    2014-11-21

    This thesis demonstrates the growing importance of deep groundwater research and the increasing demand for the development of suitable single-well test methods. At the forefront of the research on groundwater in the deep underground, radioactive waste disposal in deep geological repositories, CO{sub 2} storage, geothermal energy supply, and aquifer storage and recovery systems (ASR) are on the agenda. The developments of suitable methods for investigating these resources are a main target. Currently available methods show considerable limitations. Accordingly, comprehensive methods for the hydraulic and hydrochemical characterization of deeper aquifers with single-well access are needed. Therefore, the goal of this PhD thesis was to identify, test, and enhance potentially suitable single-well methods for characterization of groundwater flow and solute transport in such settings. For this, several Single-Well Injection-Withdrawal (&apos;'push-pull'&apos;) tracer tests were applied at the Hamasato field site (Horonobe, Japan) in a ∝100 m deep groundwater monitoring well. Aim was to characterize the impact of a dynamic saltwater-freshwater interface on a coastal aquifer. Based on the experiences of the first methodological test, a second field campaign was conducted. This campaign focused on a systematic evaluation of the push-pull tracer test method for the first time at all. The experiments focused on the investigation of the so-called &apos;'chaser'&apos; and its impact on the test results. The chaser is a specific part of many push-pull tracer tests setups. From these experiments, a specific test design for the investigation of the saltwater-freshwater interface in a single-well setting was developed. The application of this design on questions regarding different fluids within the same system, e.g. different mineralized fluids (saltwater-freshwater-interface, ASR) or temperatures (geothermal research), are promising future approaches for

  2. SAP deficiency mitigated atherosclerotic lesions in ApoE(-/-) mice.

    Science.gov (United States)

    Zheng, Lingyun; Wu, Teng; Zeng, Cuiling; Li, Xiangli; Li, Xiaoqiang; Wen, Dingwen; Ji, Tianxing; Lan, Tian; Xing, Liying; Li, Jiangchao; He, Xiaodong; Wang, Lijing

    2016-01-01

    Serum amyloid P conpoent (SAP), a member of the pentraxin family, interact with pathogens and cell debris to promote their removal by macrophages and neutrophils and is co-localized with atherosclerotic plaques in patients. However, the exact mechanism of SAP in atherogenesis is still unclear. We investigated whether SAP influence macrophage recruitment and foam cell formation and ultimately affect atherosclerotic progression. we generated apoE(-/-); SAP(-/-) (DKO) mice and fed them western diet for 4 and 8 weeks to characterize atherosclerosis development. SAP deficiency effectively reduced plaque size both in the aorta (p = 0.0006 for 4 wks; p = 0.0001 for 8 wks) and the aortic root (p = 0.0061 for 4 wks; p = 0.0079 for 8wks) compared with apoE(-/-) mice. Meanwhile, SAP deficiency inhibited oxLDL-induced foam cell formation (p = 0.0004) compared with apoE(-/-) mice and SAP treatment increases oxLDL-induced foam cell formation (p = 0.002) in RAW cells. Besides, SAP deficiency reduced macrophages recruitment (p = 0.035) in vivo and in vitro (p = 0.026). Furthermore, SAP treatment enhanced CD36 (p = 0.007) and FcγRI (p = 0.031) expression induced by oxLDL through upregulating JNK and p38 MAPK phosphorylation whereas specific JNK1/2 inhibitor reduced CD36 (p = 0.0005) and FcγRI (P = 0.0007) expression in RAW cell. SAP deficiency also significantly decreased the expression of M1 and M2 macrophage markers and inflammatory cytokines in oxLDL-induced macrophages. SAP deficiency mitigated foam cell formation and atherosclerotic development in apoE(-/-) mice, due to reduction in macrophages recruitment, polarization and pro-inflammatory cytokines and inhibition the CD36/FcγR-dependent signaling pathway. Copyright © 2015 Elsevier Ireland Ltd. All rights reserved.

  3. Tratamento conjugado de lixiviado de aterro sanitário e esgoto sanitário em lagoas de estabilização rasas

    OpenAIRE

    Campos, Andrezza Raphaella Costa

    2012-01-01

    A busca para desenvolver alternativas viáveis e eficientes para o tratamento do lixiviado de aterro sanitário, fez com que surgisse a iniciativa de pesquisar sobre o tratamento conjugado entre lixiviado de aterro sanitário e esgoto sanitário, visando tratar o lixiviado diluindo este no esgoto, reduzindo as elevadas concentrações de matéria orgânica e nitrogênio amoniacal, deixando em proporções adequadas ao tratamento convencional. Neste estudo, foi analisada a eficiência do processo de trata...

  4. &apos;Carbon-Money Exchange&apos; to contain global warming and deforestation

    Energy Technology Data Exchange (ETDEWEB)

    Nagase, Kozo E-mail: nagase@de.mbn.or.jp

    2005-07-01

    This paper builds a basic theory of &apos;Carbon-Money Exchange&apos; in which carbon as currency in nature&apos;s household (ecosystems) and money as currency in humankind&apos;s household (economy) are exchanged just like in a foreign exchange. The simple chemical equation below makes it possible (CO{sub 2}{yields}C+O{sub 2}=C+O{sub 2}{yields}CO{sub 2}). The left-hand side represents the work of plants to remove atmospheric CO{sub 2}. The right-hand side represents the work of humans as fossil fuel consumers to produce it. The exchange of the two currencies is possible by copying the fossil fuel market. The paper concludes that this new exchange can automatically contain global warming and deforestation, replacing onerous emissions trading. Moreover, it could revolutionize the conventional economy, creating counter-capitalism, or &apos;carbonism&apos;.

  5. &apos;Smart Home&apos; and energy efficiency; Smarthome und Energieeffizienz

    Energy Technology Data Exchange (ETDEWEB)

    Grieder, T.; Huser, A.

    2005-07-01

    This comprehensive final report for the Swiss Federal Office of Energy (SFOE) presents the results of a project that examined the power consumption of a &apos;smart home&apos; - a single-family dwelling in Chur, Switzerland. The house&apos;s power consumption is compared with that of a similar dwelling in 1992. The report describes the preparatory work for the project and analyses the power requirements of the various electrical consumers in the house. Comparisons are made with the electricity consumption of an average Swiss house. Possibilities of increasing efficiency are looked at. Consumption is extrapolated to national level on the basis of previous studies. A comprehensive appendix with details on the house&apos;s usage, its inhabitants&apos; needs, its multimedia concept and its technical equipment completes the report.

  6. Imaging in smoldering (asymptomatic) multiple myeloma. Past, present and future; Bildgebung bei &apos;'smoldering'&apos; (asymptomatischem) multiplem Myelom. Vergangenheit, Gegenwart und Zukunft

    Energy Technology Data Exchange (ETDEWEB)

    Bhutani, M.; Landgren, O. [Center for Cancer Research, National Cancer Institute, National Institutes of Health, Multiple Myeloma Section, Lymphoid Malignancies Branch, Bethesda, MD (United States)

    2014-06-15

    imaging techniques need to be validated in prospective clinical trials assessing the SMM to multiple myeloma transition, with the aim of enabling appropriate management decisions. Efforts are also needed to improve the costs and availability of whole-body MRI and/or FDG PET/CT, in order to facilitate their widespread adoption as first-line detection modalities. Future clinical trials of therapeutic agents using earlier detection strategies will have to be carefully designed and take into consideration the risk of lead-time and length-time biases, which might falsely demonstrate longer overall survival. The English full text version of this article is available at SpringerLink (under &apos;'Supplemental'&apos;). (orig.) [German] Aktuelle klinische Studien sprechen fuer eine Therapie des &apos;&apos;smoldering multiple myeloma&apos;&apos; (SMM) mit hohem Progressionsrisiko schon bei der Diagnosestellung und nicht erst zum Zeitpunkt der Progression in ein symptomatisches multiples Myelom (MM). Die Frueherkennung einer Knochen- und/oder Knochenmarkbeteiligung durch entsprechende sensitive Bildgebungsverfahren kann zur Ermittlung von SMM-Patienten mit hohem Risiko fuer eine Progression beitragen. Nach aktuellen Konsensusleitlinien (2011) ist die Roentgenuntersuchung des Skeletts ein Grundpfeiler der Beurteilung einer Knochenbeteiligung bei Diagnosestellung und in Verlaufskontrollen wegen eines SMM. Jedoch hat die Roentgenuntersuchung des Skeletts eine geringe Sensitivitaet fuer Knochenlaesionen und liefert keine Informationen zu Knochenmarkveraenderungen. Moderne bildgebende Verfahren wie die Fluordeoxyglukose-Positronenemissionstomographie-Computertomographie (FDG-PET-CT) und die Magnetresonanztomographie (MRT) liefern zusammen mit innovativen Funktionsuntersuchungen eine bessere Einschaetzung allgemeiner Veraenderungen im Knochenmark- und im Knochenkompartiment. Mit diesen Verfahren kann die beginnende Progression vom SMM zum MM quantitativ objektiviert werden

  7. The quantum realm of the &apos;&apos;Little Sibling&apos;&apos; of the Big Rip singularity

    International Nuclear Information System (INIS)

    Albarran, Imanol; Bouhmadi-López, Mariam; Cabral, Francisco; Martín-Moruno, Prado

    2015-01-01

    We analyse the quantum behaviour of the &apos;&apos;Little Sibling&apos;&apos; of the Big Rip singularity (LSBR) [1]. The quantisation is carried within the geometrodynamical approach given by the Wheeler-DeWitt (WDW) equation. The classical model is based on a Friedmann-Lemaître-Robertson-Walker Universe filled by a perfect fluid that can be mapped to a scalar field with phantom character. We analyse the WDW equation in two setups. In the first step, we consider the scale factor as the single degree of freedom, which from a classical perspective parametrises both the geometry and the matter content given by the perfect fluid. We then solve the WDW equation within a WKB approximation, for two factor ordering choices. On the second approach, we consider the WDW equation with two degrees of freedom: the scale factor and a scalar field. We solve the WDW equation, with the Laplace-Beltrami factor-ordering, using a Born-Oppenheimer approximation. In both approaches, we impose the DeWitt (DW) condition as a potential criterion for singularity avoidance. We conclude that in all the cases analysed the DW condition can be verified, which might be an indication that the LSBR can be avoided or smoothed in the quantum approach

  8. Tratamento nutricional dos transtornos alimentares Nutritional treatment of eating disorders

    Directory of Open Access Journals (Sweden)

    Andréa Romero Latterza

    2004-01-01

    Full Text Available Pacientes com transtornos alimentares possuem inadequações profundas no consumo, padrão e comportamento alimentar, além de diversas crenças equivocadas sobre alimentação, o que geralmente acarreta piora do estado nutricional. O tratamento nutricional visa a reverter tais alterações e promover hábitos alimentares saudáveis e melhor relação para com o alimento. Os objetivos e características do tratamento diferem para a anorexia nervosa e a bulimia nervosa, contudo, usualmente, a abordagem é dividida em duas fases: a educacional, cujas principais metas são a regularização do hábito alimentar e o aumento do conhecimento nutricional, e a experimental, que visa a propiciar maior reabilitação nutricional e mudanças mais profundas no comportamento alimentar. As evidências existentes sugerem que o tratamento nutricional promove a melhora de tais parâmetros, porém, alguns comportamentos alimentares, como a sensação de incompetência ao lidar com os alimentos, permanecem. Desta forma, mais estudos são necessários para que se possa de fato avaliar a eficácia da abordagem nutricional.Patients with eating disorders have disturbed food intake, food pattern, food behavior, and mistaken beliefs about food and nutrition, which can worsen nutritional status. The nutritional treatment aims to revert such alterations and to promote better food habits and relationship with food. The objectives and characteristics of the treatment are different for anorexia nervosa and bulimia nervosa, but usually the approach has two phases: the educational phase, whose major goals are regularization of food habits and increase of nutrition knowledge; and the experimental phase, whose targets are better nutritional rehabilitation and more complex improvements of nutritional behavior. Evidence suggests that nutritional treatment can ameliorate such parameters, but some inadequate food behaviors remain, such as feeling of incompetence while dealing with

  9. Diferentes modalidades terapêuticas no tratamento da tendinopatia do supraespinhoso

    Directory of Open Access Journals (Sweden)

    Milton Faria Junior

    2013-06-01

    Full Text Available Objetivo: Verificar a eficácia de diferentes modalidades terapêuticas no tratamento da tendinopatia do supraespinhoso. Métodos: Ensaio clínico, de abordagem quantitativa e longitudinal, realizado de janeiro de 2010 a outubro de 2011 na Clínica de Fisioterapia da Universidade de Ribeirão Preto (UNAERP. Foram selecionados 24 pacientes adultos entre 40 e 50 anos, de ambos os gêneros, com diagnóstico de tendinopatia do supraespinhoso. Eles foram divididos em três grupos: Grupo 1 - ultrassom e cinesioterapia convencional; Grupo 2 - laser e cinesioterapia convencional; e Grupo 3 - cinesioterapia aprimorada. Como critérios de avaliação, foram utilizados os questionários de DASH e McGill e a avaliação da amplitude de movimento (ADM de flexão, extensão, abdução, adução, rotação interna (RI e rotação externa (RE. Na análise estatística, foi aplicado o Modelo de Regressão com Efeitos Mistos e o teste Kruskal-Wallis, através do software SAS® 9.0. Resultados: Após os tratamentos aplicados, os 3 grupos apresentaram melhora significativa da ADM (p<0,01 para os movimentos avaliados. O Grupo 1 apresentou ganho na ADM de RI (6° e diminuição do resultado do questionário DASH (-17,5. O Grupo 3 apresentou ganhos para os movimentos de flexão (22°, extensão (10°, abdução (26°, adução (11° e RE (13°, e uma diminuição do resultado do questionário McGill (-18,5. Conclusão: A cinesioterapia aprimorada, abordando todas as estruturas do ombro, mostrou-se mais eficaz no ganho de ADM quando comparada ao tratamento de eletroterapia e cinesioterapia convencional.

  10. Diferentes modalidades terapêuticas no tratamento da tendinopatia do supraespinhoso

    Directory of Open Access Journals (Sweden)

    Gustavo Antonio Meliscki

    2014-04-01

    Full Text Available Objetivo: Verificar a eficácia de diferentes modalidades terapêuticas no tratamento da tendinopatia do supraespinhoso. Métodos: Ensaio clínico, de abordagem quantitativa e longitudinal, realizado de janeiro de 2010 a outubro de 2011 na Clínica de Fisioterapia da Universidade de Ribeirão Preto (UNAERP. Foram selecionados 24 pacientes adultos entre 40 e 50 anos, de ambos os gêneros, com diagnóstico de tendinopatia do supraespinhoso. Eles foram divididos em três grupos: Grupo 1 - ultrassom e cinesioterapia convencional; Grupo 2 - laser e cinesioterapia convencional; e Grupo 3 - cinesioterapia aprimorada. Como critérios de avaliação, foram utilizados os questionários de DASH e McGill e a avaliação da amplitude de movimento (ADM de flexão, extensão, abdução, adução, rotação interna (RI e rotação externa (RE. Na análise estatística, foi aplicado o Modelo de Regressão com Efeitos Mistos e o teste Kruskal-Wallis, através do software SAS® 9.0. Resultados: Após os tratamentos aplicados, os 3 grupos apresentaram melhora significativa da ADM (p<0,01 para os movimentos avaliados. O Grupo 1 apresentou ganho na ADM de RI (6° e diminuição do resultado do questionário DASH (-17,5. O Grupo 3 apresentou ganhos para os movimentos de flexão (22°, extensão (10°, abdução (26°, adução (11° e RE (13°, e uma diminuição do resultado do questionário McGill (-18,5. Conclusão: A cinesioterapia aprimorada, abordando todas as estruturas do ombro, mostrou-se mais eficaz no ganho de ADM quando comparada ao tratamento de eletroterapia e cinesioterapia convencional doi:10.5020/18061230.2013.p201

  11. Vaporização a laser do cervix para tratamento da neoplasia intraepitelial cervical

    Directory of Open Access Journals (Sweden)

    Euridice Maria de Almeida Figueiredo

    Full Text Available O câncer cérvico-uterino é muito comum em vários países da América Latina. As estatísticas de mortalidade e as taxas de incidência demonstram a sua real importância. O cânver cérvico-uterino freqüentemente é uma doença progressiva iniciada com mudanças intra-epiteliais, que podem se transformar em um processo invasivo, sendo o nosso objetivo tratar precocemente estas lesões quando ainda é possível a cura de 100%. Em nosso estudo prospectivo foram selecionadas 21 pacientes com neoplasia cervical intra-epitelial reatreadas pela citplogia e diagnosticadas pela histopatologia após biópsia dirigida pela colposcopia. O método terapêutico empregado foi a vaporização a laser com o CO2. Tiveram como pré-requisito os seguintes critérios: informação segura pela colposcopia da zona de transformação e afastar a presença de câncer invasivo; a neoplasia epitelial cervical deve ocupar a ectocervix sem nenhuma extensão para o canal cervical e correlação positiva entre a citologia, colposcopia e histologia. O uso de laser CO2 com microscópio permitiu precisão na aplicação e com vantagens de ser um procedimento ambulatorial diminuindo estresse cirúrgico das pacientes. Foi realizado sem anestesia e com duração média de 15 minutos. A cicatrização completou-se em torno de três semanas e com cuidados operatórios mínimos. Somente dois casos tiveram sangramento vaginal discreto no quinto e décimo dia de pós-operatório, resolvido com tamponamento vaginal por 24 horas. A colposcopia, cirurgia e o seguimento foram feitos pelo autor, tendo uma paciente sido submetida a uma segunda vaporização no quinto mês de controle. Somente uma paciente teve recidiva no 26° mês de seguimento e complementará o tratamento. As vinte outras restantes estão em controle sem recidiva de doença. Em vista dos resultados obtivemos um percentual de cura de 95%, que coincide com a literatura. O uso de laser CO2 no tratamento das neoplasias

  12. Environmental performance data in &apos;Japan Atomic Energy Agency Report 2016&apos;

    International Nuclear Information System (INIS)

    Suzuki, Yurina; Kanai, Katsuta; Sato, Sadayuki; Tatebe, Kazuaki

    2017-03-01

    In September, 2016 Japan Atomic Energy Agency (JAEA) published results of environmental activity as a part of &apos;Japan Atomic Energy Agency Report 2016&apos; concerning the activities of FY 2015 under &apos;Law Concerning the Promotion of Business Activities with Environmental Consideration by Specified Corporations, etc., by Facilitating Access to Environmental Information, and Other Measures&apos;. This report has been edited to show detailed environmental performance data in FY 2015 as the base of the &apos;Japan Atomic Energy Agency Report 2016&apos;. This report would not only ensure traceability of the data in order to enhance the reliability of the environmental report, but also make useful measures for promoting activities of environmental considerations in JAEA. (author)

  13. The &apos;mini&apos; and &apos;micro&apos; energy sources and their limitations; Les &apos;'minis'&apos; et &apos;'micros'&apos; sources d&apos;energie et leurs limites

    Energy Technology Data Exchange (ETDEWEB)

    Anon.

    2004-03-01

    The &apos;Science and defense 2003&apos; colloquium took place in Paris on December 2 and 3. It was organized by the general delegation of armament (DGA), the French atomic energy commission (CEA) with the participation of the national center of scientific research (CNRS) and the French ministry of research and new technologies. The main topic was the needs and the solutions implemented in the domain of energy sources both for civil and military portable applications. This article make a general summary of the content of this colloquium only in the domain of small power energy sources: emergence of new miniaturized portable devices (phones, computers, cameras, autonomous medical systems, wireless communication systems, soldiers equipments, drones etc..), improvement of batteries energy density and price, new needs linked with new functionalities, technological challenges (energy generation and recovery systems, miniaturized fuel-cells, use of recoverable energy sources, implantation of power sources in the human body etc..), new technological files (new electrode materials, micron- or sub-micron scale mechanical and electronic components, sensors, micro-motors, transfer of microelectronics technologies, hybrid systems..), international competition. (J.S.)

  14. Minimum joint space width (mJSW) of patellofemoral joint on standing &apos;'skyline'&apos; radiographs: test-retest reproducibility and comparison with quantitative magnetic resonance imaging (qMRI)

    Energy Technology Data Exchange (ETDEWEB)

    Simoni, Paolo; Jamali, Sanaa; Alvarez Miezentseva, Victoria [CHU de Liege, Diagnostic Imaging Departement, Domanine du Sart Tilman, Liege (Belgium); Albert, Adelin [CHU de Liege, Biostatistics Departement, Domanine du Sart Tilman, Liege (Belgium); Totterman, Saara; Schreyer, Edward; Tamez-Pena, Jose G. [Qmetrics Technologies, Rochester, NY (United States); Zobel, Bruno Beomonte [Campus Bio-Medico University, Diagnostic Imaging Departement, Rome (Italy); Gillet, Philippe [CHU de Liege, Orthopaedic surgery Department, Domanine du Sart Tilman, Liege (Belgium)

    2013-11-15

    To assess the intraobserver, interobserver, and test-retest reproducibility of minimum joint space width (mJSW) measurement of medial and lateral patellofemoral joints on standing &apos;'skyline'&apos; radiographs and to compare the mJSW of the patellofemoral joint to the mean cartilage thickness calculated by quantitative magnetic resonance imaging (qMRI). A couple of standing &apos;'skyline'&apos; radiographs of the patellofemoral joints and MRI of 55 knees of 28 volunteers (18 females, ten males, mean age, 48.5 {+-} 16.2 years) were obtained on the same day. The mJSW of the patellofemoral joint was manually measured and Kellgren and Lawrence grade (KLG) was independently assessed by two observers. The mJSW was compared to the mean cartilage thickness of patellofemoral joint calculated by qMRI. mJSW of the medial and lateral patellofemoral joint showed an excellent intraobserver agreement (interclass correlation (ICC) = 0.94 and 0.96), interobserver agreement (ICC = 0.90 and 0.95) and test-retest agreement (ICC = 0.92 and 0.96). The mJSW measured on radiographs was correlated to mean cartilage thickness calculated by qMRI (r = 0.71, p < 0.0001 for the medial PFJ and r = 0.81, p < 0.0001 for the lateral PFJ). However, there was a lack of concordance between radiographs and qMRI for extreme values of joint width and KLG. Radiographs yielded higher joint space measures than qMRI in knees with a normal joint space, while qMRI yielded higher joint space measures than radiographs in knees with joint space narrowing and higher KLG. Standing &apos;'skyline'&apos; radiographs are a reproducible tool for measuring the mJSW of the patellofemoral joint. The mJSW of the patellofemoral joint on radiographs are correlated with, but not concordant with, qMRI measurements. (orig.)

  15. Analysis of the tumor-promoting potency of 2,4,4&apos;-trichlorobiphenyl and 2,2&apos;,4,5,5&apos;-pentachlorobiphenyl in rat liver

    Energy Technology Data Exchange (ETDEWEB)

    Kunz, S.; Schmitz, H.J.; Schrenk, D. [Kaiserslautern Univ. (Germany). Dept. of Food Chemistry and Environmental Toxicology; Buchmann, A.; Schwarz, M. [Tuebingen Univ. (Germany). Inst. of Toxicology; Schilling, B.; Paepke, O. [ERGO Research, Hamburg (Germany); Robertson, L.W.; Lehmler, H.J. [Iowa Univ, Iowa City, IA (United States). Dept. of Occupational and Environmental Health

    2004-09-15

    Polychlorinated biphenyls (PCBs) are potent persistent environmental pollutants exhibiting neurotoxic, teratogenic and tumor-promoting effects in experimental animal models. PCB congeners can be divided into &apos;dioxin-like&apos; and &apos;non-dioxin-like&apos; congeners on the basis of their ability to act as aryl hydrocarbon receptor (AhR) agonists. Like the most toxic dioxin congener 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) &apos;dioxin-like&apos; PCBs bind to the AhR and show characteristic effects on the expression of AhR-regulated genes including the induction of cytochrome P450 (CYP) 1A1. On the other hand, &apos;non-dioxin-like&apos; PCB congeners have a lower or no binding affinity to the AhR, but exhibit a &apos;phenobarbital-type&apos; induction of CYP 2B1/2 activity. The tumor-promoting potency of several PCBs has been demonstrated in two-stage initiation-promotion experiments in rat liver. Preneoplastic cell clones, targets for tumor promotion, can be identified as phenotypically altered foci showing characteristic enzyme patterns including the decreased activity of adenosine triphosphatase (ATPase) or the increased expression of the placental form of gluthatione S-transferase (GSTP). In the present study, the effect of the &apos;non-dioxin-like&apos; 2,4,4&apos;-trichlorobiphenyl (PCB 28) and 2,2&apos;,4,5,5&apos;-pentachlorobiphenyl (PCB 101) on the promotion of enzyme-altered hepatic foci was investigated in female Wistar rats after initiation with diethylnitrosamine (DEN).

  16. Final report of the inter institutional project ININ-CNSNS &apos;Source Terms specific for the CNLV&apos;; Informe final del proyecto interinstitucional ININ-CNSNS &apos;Termino Fuente especifico para la CNLV&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Anaya M, R.A. [ININ, 52045 Ocoyoacac, Estado de Mexico (Mexico)

    1991-02-15

    The purpose of the project inter institutional ININ-CNSNS &apos;Source Terms Specifies for the CNLV&apos; it is the one of implanting in the computer CYBER (CDC 180-830) of the ININ, the &apos;Source Term Code Package&apos; (STCP) and to make the operation tests and corresponding operation using the data of the sample problem, for finally to liberate the package, all time that by means of the analysis of the results it is consider appropriate. In this report the results of the are presented simulation of the sequence &apos;Energy Losses external&apos; (Station blackout) and &apos;Lost total of CA with failure of the RCIC and success of the HPCS&apos; both with data of the Laguna Verde Central. (Author)

  17. Evaluation of the environmental quality objective &apos;A Safe Radiation Environment&apos;; Utvaerdering av miljoekvalitetsmaalet &apos;Saeker straalmiljoe&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Asp, Helene; Brewitz, Erica; Halvarsson, Andreas; Ljungberg, Sophie; Mjoenes, Lars; Wallberg, Petra

    2007-11-15

    The evaluation of the environmental quality objective &apos;A Safe Radiation Environment&apos; is a contribution to the Environmental Objective Council&apos;s assessment of progress towards the national environmental quality objectives. The report describes and evaluates the radiation environment in Sweden, the regulatory instruments, measures carried out and the monitoring programmes. Furthermore, the possibility of achieving the objective and its interim targets is evaluated. New measures and means of control are proposed. The proposals are directed to the government and Parliament, national authorities and other stakeholders in society. The Swedish Radiation Protection Authority (SSI) considers it possible to achieve the objective, but additional efforts are required to ensure success. Environmental monitoring, research on health effects of radiation and supervision are still important areas. Intensified efforts will be needed to change attitudes towards suntanning. Changes in the formulation of the objective and its interim targets are suggested. Today only protection against radiation in the external environment is covered by the objective. Radiation protection work has to consider all. SSI therefore suggests that the objective should extend to include workplaces and indoor environment. For the three interim targets included in &apos;A Safe Radiation Environment&apos;, changes are suggested for the interim targets for radioactive substances and electromagnetic fields. No change is suggested for the interim target for skin cancer

  18. Behavioral phenotype and BDNF differences related to apoE isoforms and sex in young transgenic mice

    DEFF Research Database (Denmark)

    Reverte, Ingrid; Klein, Anders Bue; Ratner, Cecilia

    2012-01-01

    , very little information is available on apoE2 genotype. In the present study, we have characterized behavioral and learning phenotypes in young transgenic mice apoE2, apoE3 and apoE4 of both sexes. We have also determined the levels of brain-derived neurotrophic factor (BDNF) and its receptor Trk...

  19. Persistent organochlorine pollutants and risk for skeletal fractures and impaired bone mineral density in humans. Results from the &apos;'COMPARE'&apos; project

    Energy Technology Data Exchange (ETDEWEB)

    Hagmar, L.; Wallin, E.; Joensson, B.A. [Department of Occupational and Environmental Medicine, Lund (Sweden)

    2004-09-15

    Persistent organochlorine pollutants (POP) have, in animal studies, impaired normal bone metabolism and resulted in increased bone fragility. Especially considering the dramatical increase in osteoporotic fractures in western societies during the last decades, it is a pertinent question whether a high dietary intake of POP might pose a risk for deteriorated bone quality in humans. This problem has been assessed as a part of the collaborative project &apos;'COMPARE'&apos;, funded by European Commission RD Life Science Program. As a study base we have used cohorts of Swedish fishermen&apos;s families. We have earlier shown that fishermen living at the east coast of Sweden, have a high consumption of contaminated fatty fish from the Baltic Sea and consequently relatively high exposure levels for various POPs, also compared with fishermen from the Swedish west coast. Such a discrepancy was also found for fishermen&apos;s wives. The aim of the project was to assess in epidemiological studies whether a high dietary intake of POP through fatty fish from the Baltic may result in an increased incidence of osteoporotic fractures or decreased bone mineral density (BMD). We give here an overview of the results.

  20. &apos;&apos;Rio+20 on site&apos;&apos;. Communities on their way to sustainability. Examples from Germany; &apos;&apos;Rio+20 vor Ort&apos;&apos;. Kommunen auf dem Weg zur Nachhaltigkeit. Beispiele aus Deutschland

    Energy Technology Data Exchange (ETDEWEB)

    Nolting, Katrin; Goell, Edgar

    2012-03-15

    20 years ago, the international community adopted the concept of &apos;sustainable development&apos; as a model for the 21st century adopted in order to meet the growing challenges facing the mankind. With Agenda 21, the UN presented a global action plan for the implementation of such a sustainable development. This brochure provides an insight into sustainability activities at local level in Germany. It is shown how such activities result in future-oriented and exemplary developments in some areas and selected areas of action.

  1. Intelligent marketing of electricity from decentral power sources. Project results of the research project &apos;'Massig'&apos;; Intelligente Vermarktung von Strom aus dezentralen Energiequellen. Projektergebnisse des Forschungsvorhabens &apos;'Massig'&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Erge, Thomas; Sauer, Christian [Fraunhofer-Institut fuer Solare Energiesysteme ISE, Freiburg (Germany); Barnsteiner, Martin; Preiser, Klaus [Badenova Waermeplus GmbH und Co.KG, Freiburg (Germany)

    2011-07-01

    In the European research project &apos;Market Access for Smaller Size Intelligent Electricity Generation (Massig)&apos; scientists at the Fraunhofer Institute for Solar Energy Systems (Freiburg, Federal Republic of Germany) examined together with project partners the demand-oriented supply and commercialization of electricity from decentral power generators at the liberalized electricity market. The project team selected target countries and evaluated innovative solutions of marketing especially for specific applications of practice. Such a model project is that of Badenova Waermeplus GmbH (Freiburg, Federal Republic of Germany).

  2. Tratamento de sementes com bioestimulante ao milho submetido a diferentes variabilidades na distribuição espacial das plantas

    Directory of Open Access Journals (Sweden)

    Daniel Fernando Kolling

    2016-02-01

    Full Text Available RESUMO: A utilização de bioestimulantes pode auxiliar a mitigar os prejuízos ao milho, ocasionados pela má qualidade de estande. Este trabalho foi conduzido objetivando avaliar o efeito do tratamento de sementes com bioestimulante sobre o desempenho agronômico do milho, submetido a diferentes níveis de variabilidade na distribuição espacial das plantas na linha de semeadura. O experimento foi implantado em Lages, SC, durante o ano agrícola de 2013/2014. O delineamento experimental foi de blocos ao acaso, dispostos em parcelas subdivididas. Nas parcelas principais, testaram-se três níveis de desuniformidade espacial na linha: 0, 50 e 100% do Coeficiente de Variação (CV. No nível 0 % de CV, todas as sementes foram uniformemente distribuídas no sulco de semeadura, a uma distância de 17cm entre si. Nos demais níveis de CV, as distâncias entre sementes variaram conforme o tratamento. Nas subparcelas, testou-se a presença ou ausência do tratamento de sementes com bioestimulante. O aumento da variabilidade na distribuição espacial das plantas reduziu a área foliar e o teor de clorofila da folha índice no espigamento, bem como o diâmetro do colmo na colheita, independentemente do tratamento de sementes com bioestimulante. Isso contribuiu para reduzir o número de grãos por espiga e o rendimento de grãos dos tratamentos com 50 e 100% de CV na variabilidade espacial, tanto na presença quanto na ausência do bioestimulante. Portanto, o tratamento de sementes com bioestimulante não mitigou os prejuízos ao rendimento de grãos do milho ocasionados pela distribuição espacial irregular das plantas na linha de semeadura.

  3. Chances and perspectives of hybrid vehicles; &apos;&apos;Chancen und Perspektiven von Hybridfahrzeugen&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Taenzer, Guillem [IZES gGmbH, Saarbruecken (Germany)

    2009-07-01

    It is still a challenge for the global automotive industry to build environment friendly and sustainable cars. One of the main questions is which possibilities and prospects short- and long term can be used to maintain the mobility standard today? Hybrid cars could be a short term option (such as 10 to 20 years) to serve as temporary solution. In conjunction with bio fuel hybrid cars could be a sustainable solution - but the today&apos;s availability of bio fuel doesn&apos;t cover the current and future demand of bio fuel. In this context the foodstuff production and the cultivation of monocultures shouldn&apos;t be disregarded. The enhancements of electrical components by hybrid cars allows to get access to the potential of electro mobility (middle term perspectives), even in conjunction with a fuel cell (long term perspectives). Still unresolved are the quantitative allocation of hydrogen (by renewable energy) and the infrastructure of a hydrogen system. (orig.)

  4. The Novel SCN&apos;&apos;- Ion-selective Electrode Based on the 1-Benzyl-3-(4-nitrophenyl) thio-urea Ionophore

    Energy Technology Data Exchange (ETDEWEB)

    Lee, Kyung Mi; Kang, Dong Hyeon; Choe, Ju Eun; You, Jung Min; Go, Min Jeong; Lee, Jung Seong; Jeon, Seung Won [Chungnam National University, Daejeon (Korea, Republic of)

    2014-09-15

    A potentiometric sensor based on the 1-benzyl-3-(4-nitrophenyl) thio-urea was synthesized and tested as an ionophore in PVC based membrane sensor towards SCN - ions. This membrane exhibits a linear stable response over a wide concentration range (1.0 × 10&apos;&apos;-5 to 1.0 × 10&apos;&apos;-2 M) with a slope of -59.2 mV/dec., a detection limit of log[SCN&apos;&apos;- ] = -5.05, and a selectivity coefficient for thiocyanate against perchlorate anion of logK{sub s}cn&apos;&apos;pot = -0.133. The selectivity series of the membrane is as follows: SCN&apos;&apos;- > ClO{sub 4}&apos;&apos;- > I&apos;&apos;- >NO{sub 3}&apos;&apos;- >HSO{sub 3}&apos;&apos;- > Cl&apos;&apos;-HSO{sub &apos;}'-'&apos;4 > F&apos;&apos;- > CH{sub 3}COO&apos;&apos;- > HCO&apos;'-'&apos;3 > Br&apos;&apos;- > H{sub 2}PO{sub 4}&apos;&apos;- > SO{sub 3}&apos;'-'&apos;2 > SO{sub 4}&apos;'-'&apos;2 > CO{sub 3}&apos;'-'&apos;2. The proposed electrode showed good selectivity and a good response for the SCN&apos;&apos;- ion over a wide variety of other anions in pH 6.0 buffer solutions and has a fast response time of about < 5s.. The influences of the membrane by pH, ionophore, and plasticizer were studied.

  5. Usuários de Crack que Buscam Tratamento em Brasília

    Directory of Open Access Journals (Sweden)

    Maria Inês Gandolfo Conceição

    Full Text Available RESUMO Objetivando identificar o perfil de pacientes ambulatoriais que procuram tratamento para problemas relacionados com crack em Brasília, 132 usuários que recebem serviços psicológicos preencheram o Questionário sobre o Perfil de Consumo de Crack e o Cocaine Craving Questionnaire-Brief. Os participantes eram homens (83,6%, solteiros (38,8% e possuíam residência (100%. O primeiro uso foi motivado pela curiosidade (65,9%, influência dos pares (58,3% e fácil acesso (50,8%. A maioria (65,2% relatou poliuso. O mais longo período de abstinência foi de quatro anos (1,5% e a maioria (46% relatou menos de 30 dias. O poder letal, dependência e contextos de vulnerabilidade social associados ao crack foram questionados neste estudo. São necessários esforços para melhor atender aos que não acessam o sistema de tratamento.

  6. If science does create more than knowledge. A congress is asking for &apos;education by science&apos;; Wenn Wissenschaft mehr als Wissen schafft. Ein Kongress fragt nach &apos;Bildung durch Wissenschaft&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Nuissl, E. (ed.)

    2002-07-01

    The role of science in the development of the so-called &apos;knowledge society&apos; was investigated at this interdisciplinary congress. Three problem areas were identified: 1. Science itself must constantly review its own ethical fundamentals and investigate and extend its ability to keep a dialogue running. 2. Society is asked to provide an ethical and moral orientation for dealing with newly acquired knowledge and to define the social standing of science. 3. Each and every individual must work on maintaining and extending his or her level of knowledge in order to cope with everyday life and perform social functions. [German] Ziel des Kongresses &apos;&apos;Bildung durch Wissenschaft&apos;&apos; war es, im interdisziplinaeren Austausch die Rolle der Wissenschaft bei der Entwicklung der so genannten &apos;'Wissensgesellschaft'&apos; zu eroertern. Der enorme Wissenszuwachs des vergangenen Jahrhunderts bedeutet eine Zunahme des &apos;'Machbaren'&apos;, von dessen positiven wie negativen Folgen die Gesellschaft und der Einzelne gleichermassen betroffen ist. Das gilt gerade fuer diejenigen Technologien und Wissensbestaende, die im Alltag von Bedeutung sind. Der Kongress beschaeftigte sich mit diesen Entwicklungen und mit den Problemen, die sich daraus ergeben. Der erste Problemkreis betrifft die Wissenschaft selbst: Sie muss sich ihrer eigenen ethischen Grundlagen wieder neu vergewissern, ihre Dialogfaehigkeit ueberpruefen und erweitern. Ein zweiter Problemkreis ist auf Seiten der Oeffentlichkeit auszumachen: Die Gesellschaft wird ethische und moralische Orientierungen fuer den Umgang mit dem neu erworbenen Wissen schaffen und grundsaetzlich den gesellschaftlichen Stellenwert der Wissenschaft bestimmen muessen. Der dritte Problemkreis stellt sich dem Einzelnen: Jeder ist gefordert, kontinuierlich sein Wissensniveau zu erhalten und zu erweitern, um den Alltag bewaeltigen und gesellschaftliche Aufgaben wahrnehmen zu koennen. (orig.)

  7. Green economy. From theory to practice; &apos;Green Economy&apos;. Von der Theorie zur Praxis

    Energy Technology Data Exchange (ETDEWEB)

    Wackerbauer, Johann [ifo Institut, Muenchen (Germany)

    2013-04-15

    The topic of &apos;&apos;green economy&apos;&apos; took centre stage at last year&apos;s UN conference on sustainable development in Rio de Janeiro. The term &apos;&apos;green economy&apos;&apos; has many interpretations to it, ranging from an emphasis on energy and resource efficiency in an otherwise ordinary economy to positions that are critical of growth as such. What can be considered as the essence of the concept of green economy, and what challenges need to be mastered on the way there? The present study shows that there is more to the term than most companies and consumers are aware of.

  8. Acetabular retroversion as a rare cause of chronic hip pain: recognition of the &apos;'figure-eight'&apos; sign

    Energy Technology Data Exchange (ETDEWEB)

    Banks, Kevin P. [Brooke Army Medical Center, Department of Radiology, Fort Sam Houston, TX (United States); Grayson, David E. [Wilford Hall Medical Center, Department of Radiology, Lackland Air Force Base, TX (United States)

    2007-06-15

    While well-recognized in the orthopedic literature as a cause of chronic hip pain, acetabular retroversion has not been specifically described in the radiologic literature. Acetabular retroversion represents a particular form of hip dysplasia characterized by abnormal posterolateral orientation of the acetabulum. This pathophysiology predisposes the individual to subsequent anterior impingement of the femoral neck upon the anterior acetabular margin and fibrous labrum. Without treatment, cases may progress to damage of the anterior labrum and cartilage, with eventual early onset of osteoarthritic disease. This impinging condition has been described as occurring in isolation or as part of a complex dysplasia. We describe two cases of acetabular retroversion diagnosed by conventional radiographic evaluation of the pelvis, one in isolation and one occurring in the setting of a larger congenital syndrome. These cases illustrate the utility of the &apos;'figure-eight'&apos; sign in identifying abnormalities of acetabular version and thus assisting clinicians in properly identifying these individuals so that appropriate therapy may be instituted. (orig.)

  9. Tratamento térmico de berilo incolor (goshenita) e colorido (água-marinha, heliodoro e morganita)

    OpenAIRE

    Polli, Gabriel de Oliveira

    2006-01-01

    Programa de Pós-Graduação em Evolução Crustal e Recursos Naturais. Departamento de Geologia. Escola de Minas, Universidade Federal de Ouro Preto. A comercialização de grande parte do mineral-gema berilo depende de tratamento térmico mplamente utilizado para água-marinha (azul e verde), morganita e heliodoro, com o objetivo de melhorar ou modificar a cor natural e, assim, agregar valor à gema. Na aplicação do tratamento térmico, devem ser levadas em consideração as mudanças físico-químicas ...

  10. Terapia fotodinâmica para tratamento de candidíase vulvovaginal em modelo experimental com camundongas

    OpenAIRE

    Santi, Maria Eugenia Simões Onofre de

    2014-01-01

    Candidíase vulvovaginal é a segunda mais comum infecção ginecológica e afeta 75% das mulheres pelo menos uma vez durante seu período reprodutivo. A candidíase vulvovaginal recorrente representa um desafio à prática ginecológica, uma vez que muitas pacientes experimentam recorrências imediatamente após finalizarem um tratamento. A terapia fotodinâmica (PDT) é considerada uma abordagem terapêutica no tratamento de infecções fúngicas. O objetivo deste estudo foi investigar a eficácia da PDT em v...

  11. Germany steps up pressure on Fessenheim, but is the &apos;Energiewende&apos; all-knowing?

    International Nuclear Information System (INIS)

    Shepherd, John

    2015-01-01

    Politics of course has more than its fair share of those who know everything and do their best not to let get the facts get in the way where inconvenient truths risk destroying their &apos;'Besserwisser'&apos; illusions. An example of this is a letter from Germany&apos;s federal environment minister Barbara Hendricks to her French counterpart Segolene Royal. The subject of the letter was the closure of France&apos;s Fessenheim nuclear power plant. The content of the letter appears to show that, not content with stamping out the use of nuclear energy in Germany and all the knowledge and industrial expertise that goes with it, Germany seems intent on imposing its point of view onto its neighbour. Hendricks acknowledges that any decisions relating to Fessenheim are for France alone as a sovereign nation. But, if that is the case, why bother to write the letter in the first place? In reply Royal, a prominent French Socialist, stresses French president Francois Hollande&apos;s desire to close Fessenheim before his term of office draws to a close. Royal also noted that it is up to France&apos;s nuclear operator, EDF, to &apos;&apos;define which reactors are removed from the grid&apos;&apos;. It is also amusing to read Royal&apos;s comment that the fact Fessenheim can be closed at all is largely due to the construction of replacement nuclear capacity at Flamanville, in northern France. Surely that irony could not have been lost on Germany&apos;s environment ministry.

  12. Germany steps up pressure on Fessenheim, but is the &apos;Energiewende&apos; all-knowing?

    Energy Technology Data Exchange (ETDEWEB)

    Shepherd, John [nuclear 24, Brighton (United Kingdom)

    2015-04-15

    Politics of course has more than its fair share of those who know everything and do their best not to let get the facts get in the way where inconvenient truths risk destroying their &apos;'Besserwisser'&apos; illusions. An example of this is a letter from Germany&apos;s federal environment minister Barbara Hendricks to her French counterpart Segolene Royal. The subject of the letter was the closure of France&apos;s Fessenheim nuclear power plant. The content of the letter appears to show that, not content with stamping out the use of nuclear energy in Germany and all the knowledge and industrial expertise that goes with it, Germany seems intent on imposing its point of view onto its neighbour. Hendricks acknowledges that any decisions relating to Fessenheim are for France alone as a sovereign nation. But, if that is the case, why bother to write the letter in the first place? In reply Royal, a prominent French Socialist, stresses French president Francois Hollande&apos;s desire to close Fessenheim before his term of office draws to a close. Royal also noted that it is up to France&apos;s nuclear operator, EDF, to &apos;&apos;define which reactors are removed from the grid&apos;&apos;. It is also amusing to read Royal&apos;s comment that the fact Fessenheim can be closed at all is largely due to the construction of replacement nuclear capacity at Flamanville, in northern France. Surely that irony could not have been lost on Germany&apos;s environment ministry.

  13. Tratamento das fraturas do processo odontóide Treatment of odontoid fractures

    Directory of Open Access Journals (Sweden)

    Pedro Augusto Pontin

    2011-01-01

    Full Text Available OBJETIVO: Este artigo faz a avaliação retrospectiva clínica e radiológica das fraturas do odontóide de 20 pacientes atendidos no IOT-HCFMUSP, durante o período de 2004-2010. MÉTODOS: Foi realizado a estratificação destas fraturas segundo sua classificação (AO/Anderson e D'Alonzo, perfil epidemiológico, tipo de tratamento, tempo de consolidação e complicações. RESULTADOS: Observou-se maior número de casos da fratura do odontóide em pacientes do sexo masculino (4:1, com idade entre 3ª e 4ª década de vida (60%, vítimas de quedas de altura (60% e acidentes automobilísticos (25% como principais mecanismos de trauma, e 15% dos casos apresentaram-se com déficit neurológico. A fraturas do odontóide de maior prevalência foram as do tipo II (55%, seguidas pelas fraturas do tipo III (40%. Os tratamentos mais empregados nas fraturas do tipo II e III foram, respectivamente, o cirúrgico (73% e conservador (87,5%. A consolidação ocorreu em até 16 semanas para 87,5% dos casos de tratamento cirúrgico e para 54,5% dos tratados conservadoramente. Não houve casos de pseudoartrose. CONCLUSÃO: O tratamento cirúrgico das fraturas do odontóide do tipo II apresentou resultados satisfatórios em relação ao tempo consolidação e baixa incidência de complicações, bem como o tratamento conservador destinado às fraturas do tipo III.Nivel de Evidência IV, série de casos.OBJECTIVE: This article describes a clinical and radiologic retrospective analysis of odontoid fractures in20 patients accompanied byThe IOT-HCFMUSP,from 2004 to 2010. METHODS: These fractures were stratified according to their classification (AO/Anderson andD'Alonzo, epidemiologic profile, type of treatment, time to consolidation of the fracture, and complications. RESULTS: It was observed that there was a higher number of odontoid fractures in males (4:1, between the third and fourth decades of life (60%, and that the main causes of the trauma were falling from

  14. Electroconvulsive therapy in treatment-resistant mania: case reports A Eletroconvulsoterapia no tratamento da mania resistente: relatos de casos

    Directory of Open Access Journals (Sweden)

    Marcia Britto de Macedo Soares

    2002-02-01

    Full Text Available Electroconvulsive therapy is known to be effective in the treatment of mood disorders, more specifically for depression and mania. Although a large body of evidence confirms the efficacy of electroconvulsive therapy in the treatment of mania, few prospective studies have been done to assess its effectiveness in treatment-resistant manic episodes. These case reports describe the initial results of a study that is being conducted to evaluate the efficacy of Electroconvulsive therapy among treatment-resistant bipolar patients. METHODS: Three manic patients (according to DSM-IV criteria who were considered treatment-resistant underwent a series of 12 bilateral Electroconvulsive therapy sessions. Before the treatment and then weekly, they were evaluated with the following rating scales: Young Mania Rating Scale, Hamilton Rating Scale for Depression, Brief Psychiatric Rating Scale, and Clinical Global Impressions-Bipolar Version. RESULTS: The 3 patients showed a satisfactory response to Electroconvulsive therapy, although some differences in the course of response were observed. CONCLUSION: These case reports suggest that Electroconvulsive therapy needs further evaluation for the treatment of resistant bipolar patients.A Eletroconvulsoterapia é uma alternativa reconhecidamente eficaz no tratamento dos transtornos do humor. Embora vários estudos tenham confirmado a eficácia desta modalidade terapêutica no tratamento da mania aguda, poucos estudos foram realizados em pacientes maníacos resistentes à farmacoterapia. Esses relatos de casos descrevem resultados preliminares de um projeto de pesquisa que tem por objetivo avaliar a eficácia da Eletroconvulsoterapia no tratamento de transtornos bipolares resistentes. MÉTODOS: Três pacientes com diagnóstico de mania (de acordo com os critérios do DSM-IV, considerados resistentes ao tratamento medicamentoso, foram submetidos a 12 aplicações bilaterais de Eletroconvulsoterapia. Antes do tratamento e

  15. The &apos;last mile&apos; of data handling: Fermilab&apos;s IFDH tools

    International Nuclear Information System (INIS)

    Lyon, Adam L; Mengel, Marc W

    2014-01-01

    IFDH (Intensity Frontier Data Handling), is a suite of tools for data movement tasks for Fermilab experiments and is an important part of the FIFE[2] (Fabric for Intensity Frontier [1] Experiments) initiative described at this conference. IFDH encompasses moving input data from caches or storage elements to compute nodes (the &apos;last mile&apos; of data movement) and moving output data potentially to those caches as part of the journey back to the user. IFDH also involves throttling and locking to ensure that large numbers of jobs do not cause data movement bottlenecks. IFDH is realized as an easy to use layer that users call in their job scripts (e.g. &apos;ifdh cp&apos;), hiding the low level data movement tools. One advantage of this layer is that the underlying low level tools can be selected or changed without the need for the user to alter their scripts. Logging and performance monitoring can also be added easily. This system will be presented in detail as well as its impact on the ease of data handling at Fermilab experiments.

  16. Fatores associados à adesão ao tratamento de crianças e adolescentes com doenças reumáticas crônicas

    Directory of Open Access Journals (Sweden)

    Vanessa M. Bugni

    2012-12-01

    Full Text Available OBJETIVO: São vários os fatores que contribuem para a má adesão ao tratamento de crianças e adolescentes com doenças reumáticas crônicas, gerando piora da qualidade de vida e do prognóstico. Nosso objetivo foi avaliar as taxas de adesão ao tratamento e identificar os fatores socioeconômicos e clínicos associados. MÉTODOS: Foram incluídos 99 pacientes com artrite idiopática juvenil, lúpus eritematoso sistêmico, dermatomiosite ou esclerodermia juvenil. Todos os pacientes eram acompanhados no ambulatório de reumatologia pediátrica por um período mínimo de 6 meses. Para avaliação da adesão, foi aplicado aos cuidadores um questionário composto por três blocos: 1 dados demográficos, clínicos e laboratoriais; 2 adesão ao tratamento medicamentoso; e 3 comparecimento às consultas, realização de exames e utilização de órteses. Foi considerada má adesão, quando realizado valor menor ou igual a 80% do prescrito. RESULTADOS: Um total de 53% dos pacientes apresentou boa adesão ao tratamento global, observada quando o cuidador possuía união estável (p = 0,006; 20 pacientes (20,2% apresentaram má adesão ao tratamento medicamentoso, relacionada à utilização de mais que três medicamentos diários (p = 0,047. As causas de má adesão ao tratamento foram esquecimento, recusa, dose incorreta ou falta de medicamento, problemas pessoais e dificuldades financeiras. CONCLUSÕES: Observamos boa adesão ao tratamento global nos pacientes cujos cuidadores possuíam união estável e má adesão ao tratamento medicamentoso nos pacientes que utilizavam mais que três tipos de medicamentos diariamente. Não houve associação entre as taxas de adesão ao tratamento e sexo, idade, tempo de diagnóstico e atividade da doença.

  17. Triglyceride-rich lipoprotein metabolism in women: roles of apoC-II and apoC-III.

    Science.gov (United States)

    Ooi, Esther M; Chan, Dick C; Hodson, Leanne; Adiels, Martin; Boren, Jan; Karpe, Fredrik; Fielding, Barbara A; Watts, Gerald F; Barrett, P Hugh R

    2016-08-01

    Experimental data suggest that apolipoprotein (apo) C-II and C-III regulate triglyceride-rich lipoprotein (TRL) metabolism, but there are limited studies in humans. We investigated the metabolic associations of TRLs with apoC-II and apoC-III concentrations and kinetics in women. The kinetics of plasma apoC-II, apoC-III and very low-density lipoprotein (VLDL) apoB-100 and triglycerides were measured in the postabsorptive state using stable isotopic techniques and compartmental modelling in 60 women with wide-ranging body mass index (19·5-32·9 kg/m(2) ). Plasma apoC-II and apoC-III concentrations were positively associated with the concentrations of plasma triglycerides, VLDL1 - and VLDL2 -apoB-100 and triglyceride (all P triglyceride concentration and VLDL1 triglyceride PR, while apoC-II fractional catabolic rate (FCR) was positively associated with VLDL1 triglyceride FCR (all P triglyceride kinetics. ApoC-III PR, but not FCR, was positively associated with VLDL1 triglyceride, and VLDL2 -apoB-100 and triglyceride concentrations (all P triglyceride kinetics. In multivariable analysis, including homoeostasis model assessment score, menopausal status and obesity, apoC-II concentration was significantly associated with plasma triglyceride, VLDL1 -apoB-100 and VLDL1 triglyceride concentrations and PR. Using the same multivariable analysis, apoC-III was significantly associated with plasma triglyceride and VLDL1 - and VLDL2 -apoB-100 and triglyceride concentrations and FCR. In women, plasma apoC-II and apoC-III concentrations are regulated by their respective PR and are significant, independent determinants of the kinetics and plasma concentrations of TRLs. © 2016 Stichting European Society for Clinical Investigation Journal Foundation.

  18. The Palestinian Authority and &apos;Climate Change&apos; as an Emergent Public Problem

    International Nuclear Information System (INIS)

    Fustec, Klervi

    2014-01-01

    &apos;Climate change&apos; is an oft avowed environmental priority among cooperation and development actors. The Palestinian Territories, for their part, are one of the largest recipients of international aid. To the degree that the UNPD has played a role in promoting the question of &apos;climate change&apos;, the dependence of the Palestinian Authority on international aid has contributed to framing this emergent public problem; its construction is anchored in the context of the Israeli-Palestinian conflict and the Palestinian state&apos;s demand for recognition at the international level. In the international arenas dedicated to &apos;climate change&apos;, what&apos;s more, the Palestinian Authority discusses this question in terms of political and climatic injustice. Two questions thus merit study: what effect does the construction of the climate problem have on the Palestinian Authority and, conversely, what effect does the Palestinian Authority have on the construction of the climate problem?

  19. Baseline for trust: defining &apos;new and additional&apos; climate funding

    Energy Technology Data Exchange (ETDEWEB)

    Stadelmann, Martin [University of Zurich (Switzerland); Roberts, J. Timmons [Brown University (United States); Huq, Saleemul

    2010-06-15

    Climate finance is becoming a dark curve on the road from Copenhagen to Cancún. Poorer nations fear that richer ones will fulfil the US$30 billion &apos;fast-start&apos; climate finance promises made in the non-binding Copenhagen Accord by relabelling or diverting basic development aid, or by simply delivering on past climate finance pledges. The problem is simple: contributor countries are operating with no clear baseline against which their promise of &apos;new and additional&apos; funding can be counted – and they do not accept the baselines put forth by developing countries. A viable solution for the short term is to use projections of business-as-usual development assistance as baselines. The longer-term benchmark could be the provision of truly &apos;new&apos; funds from new funding sources. Substantial up-front negotiations may be required, but seizing this opportunity to define baselines will build confidence on both sides and create predictability for future finance.

  20. Tratamento da tuberculose de infecção latente. As recomendações actuais

    Directory of Open Access Journals (Sweden)

    R. Duarte

    2010-09-01

    Full Text Available Resumo: O diagnóstico e tratamento da infecção latente por Mycobacterium tuberculosis reduz significativamente o risco de desenvolvimento de tuberculose activa e a transmissão da doença na comunidade. O rastreio da tuberculose infecção latente deve passar pela exclusão de doença activa (inquérito de sintomas e radiografia pulmonar e avaliação da resposta imunológica ao M. tuberculosis através dos testes actualmente ao dispor, como o teste tuberculínico e os testes IGRA (interferon-gamma release assay. A escolha do esquema de tratamento deve ter em linha de conta a eficácia, a adesão e os efeitos colaterais associados ao mesmo Este documento actualiza as recomendações sobre tratamento da tuberculose infecção latente. São apresentadas indicações sobre quem deve ser rastreado e revistos os esquemas de tratamento. Abstract: Diagnosis and treatment of latent infection with Mycobacterium tuberculosis (LTBI, significantly reduces the risk of developing active tuberculosis and the transmission of the disease in the community. LTBI screening must pass by the exclusion of active disease (symptoms enquiry and chest radiography and assessment of immune response to Mycobacterium tuberculosis testing with the tests currently available – tuberculin skin test and interferon-gamma release assay (IGRA. The choice of treatment must take into account the efficacy and side effects associated with the same. This document provides updated recommendations on latent tuberculosis infection treatment. Topics covered include whom to test for TB and reviewed LTBI treatment regimens. Palavras-chave: Tuberculose, tuberculose infeccao latente, tratamento, preventivo, Key words: Tuberculosis, latent tuberculosis infection, treatment, preventive

  1. Tratamento dos distúrbios da voz na doença de Parkinson: o método Lee Silverman

    Directory of Open Access Journals (Sweden)

    Dias Alice Estevo

    2003-01-01

    Full Text Available Alterações discretas na qualidade da voz e da articulação podem ser observadas em fases relativamente iniciais da doença de Parkinson (DP. As alterações da voz e da fala na DP constituem, em conjunto, o que se denomina disartria hipocinética ou disartrofonia e caracterizam-se por monotonia e redução da intensidade da voz, articulação imprecisa e distúrbios do ritmo. Recentemente, foram relatados resultados favoráveis através de método de tratamento intensivo e dirigido especificamente para o tratamento da voz na DP, denominado Lee Silverman Voice Treatment (LSVT®. O objetivo essencial desse método é aumentar a intensidade vocal através do incremento do esforço fonatório. O presente estudo teve por objetivo a caracterização das anormalidades vocais (qualidade vocal, padrão articulatório e inteligibilidade em um grupo de pacientes com DP e a avaliação da resposta terapêutica obtida pela administração do método Lee Silverman. A comparação dos dados de análise acústica, bem como da análise perceptivo-auditiva nos períodos pré e pós-tratamento mostraram modificações estatisticamente significantes após o tratamento. Embora o padrão articulatório tenha se mantido impreciso, os benefícios obtidos pelo tratamento na melhora da qualidade vocal e, sobretudo, na intensidade vocal favoreceram a qualidade da comunicação oral, reduziram os sintomas negativos e adequaram a qualidade vocal às necessidades pessoais e sociais dos indivíduos.

  2. &apos;Chernobyl&apos; reaches Norway: the accident, science, and the threat to cultural knowledge

    Energy Technology Data Exchange (ETDEWEB)

    Paine, R. (Memorial Univ. of Newfoundland, St. John' s, NF (Canada))

    1992-07-01

    This report is interested in the transitions that &apos;Chernobyl&apos; underwent in Norway. It &apos;arrived&apos; as a ghastly accident: important cultural routines were disturbed, apprehension ran high, and the country waited for scientists to &apos;repair&apos; the accident. The scourge of radiation, however, still covered much of the countryside of central Norway. Reindeer pastures were heavily polluted, and among Saami (Lapp) groups there arose a cognitive sense of disruption to a way of life. Ambivalent relations - at times cooperative, more often adversarial - developed among the Saami in respect to the outside experts who strove to bring the radiation problem under control. The report (with anthropological fieldwork) strives to show how much of the problem of &apos;Chernobyl&apos;, in this later phase, has to do with the different nature of the claims of two kinds of knowledge: the outside scientists&apos; and the Saami pastoralists. (author).

  3. Large-scale offshore wind farms in Denmark. Update of &apos;&apos;Future offshore sites for wind turbines 2025&apos;&apos;; Stor-skala havmoelleparker i Danmark. Opdatering af fremtidens havmoelleplaceringer

    Energy Technology Data Exchange (ETDEWEB)

    2011-04-15

    This updating of the &apos;&apos;Future offshore sites for wind turbines 2025&apos;&apos;, is made by the Offshore Wind Farm Committee and adjusts primarily the existing sites in relation to a updated data basis. The sites are adjusted within the already identified areas, and no new areas are therefore included. In addition to an update of the underlying data base, including the revised sailing routes, the new Natura 2000 sites and mineral resources, there are now further collected knowledge about the seabed in the designated areas. Moreover, the underlying assumptions for construction costs and grid connection updated, which has resulted in a revised socio-economic priority of the areas. The Offshore Wind Farm Committee&apos;s report confirms that the placement of the 600 MW Kriegers Flak Offshore Wind Farm in the Baltic Sea is the best location for Denmark&apos;s next major offshore wind farm. Kriegers Flak Offshore Wind Farm is already included in the Government&apos;s energy strategy. (LN)

  4. The &apos;&apos;2T&apos;&apos; ion-electron semi-analytic shock solution for code-comparison with xRAGE: A report for FY16

    International Nuclear Information System (INIS)

    Ferguson, Jim Michael

    2016-01-01

    This report documents an effort to generate the semi-analytic &apos;2T&apos; ion-electron shock solution developed in the paper by Masser, Wohlbier, and Lowrie, and the initial attempts to understand how to use this solution as a code-verification tool for one of LANL&apos;s ASC codes, xRAGE. Most of the work so far has gone into generating the semi-analytic solution. Considerable effort will go into understanding how to write the xRAGE input deck that both matches the boundary conditions imposed by the solution, and also what physics models must be implemented within the semi-analytic solution itself to match the model assumptions inherit within xRAGE. Therefore, most of this report focuses on deriving the equations for the semi-analytic 1D-planar time-independent &apos;2T&apos; ion-electron shock solution, and is written in a style that is intended to provide clear guidance for anyone writing their own solver.

  5. Tratamento medicamentoso da osteoartrose do joelho Drug therapy in knee osteoarthrosis

    Directory of Open Access Journals (Sweden)

    Márcia Uchôa de Rezende

    2009-02-01

    Full Text Available O tratamento clínico da osteoartrite/artrose (OA está sempre indicado e baseia-se no autocuidado feito pelo paciente e orientado pelo médico. O uso de medicamentos é complementar às medidas de emagrecimento, ganho de força, de propriocepção, de flexibilidade e de amplitude de movimento. Entre os medicamentos disponíveis para o tratamento da OA há os que são essencialmente analgésicos e que não interferem no curso da doença; bem como os anti-inflamatórios, controversos por seus efeitos colaterais e pelo seu papel na OA, porém, com propriedades analgésicas e anti-inflamatórias indiscutíveis; e, por fim, as drogas modificadoras de estrutura, que retardam a evolução da OA. As medicações ainda podem ser de uso tópico, intra-articular, oral e injetável (sistêmico. As várias apresentações de ácido hialurônico (AH mostram o poder analgésico da droga e há indícios de poder modificador de estrutura da cartilagem pela medicação. Há nível de evidência IA, para diacereína e para a glucosamina, de que retardam a evolução da OA. Mais tecnologia para diagnóstico e controle de tratamento da OA, bem como mais estudos multicêntricos são necessários para consolidar o poder do tratamento medicamentoso de outras drogas.Clinical treatment for osteoarthritis (OA is very important and is based on patient's self care and guided by the physician. Drug therapy is additional to losing weight, improving muscular strength, proprioception, flexibility and range of motion. Between the available drugs for osteoarthritis' treatment, some are basically analgesics and do not interfere on disease's progression; some are anti-inflammatory with good analgesic power but with side effects that compromise their prolonged usage; and the structure modifying drugs that slow down the progression of OA. The medications are presented in topic, oral, intra-muscular, intra-venous and intra-articular forms. The hyaluronic acid has various

  6. Folate targeted polymeric &apos;green&apos; nanotherapy for cancer

    Energy Technology Data Exchange (ETDEWEB)

    Narayanan, Sreeja; Binulal, N S; Mony, Ullas; Manzoor, Koyakutty; Nair, Shantikumar; Menon, Deepthy, E-mail: deepthymenon@aims.amrita.edu [Amrita Center for Nanosciences and Molecular Medicine, Amrita Vishwa Vidyapeetham, Kochi-682 041, Kerala (India)

    2010-07-16

    The concept of &apos;green&apos; chemotherapy by employing targeted nanoparticle mediated delivery to enhance the efficacy of phytomedicines is reported. Poly (lactide-co-glycolide) (PLGA) nanoparticles encapsulating a well known nutraceutical namely, grape seed extract (GSE)-&apos;NanoGSE&apos;-was prepared by a nanoprecipitation technique. The drug-loaded nanoparticles of size {approx} 100 nm exhibited high colloidal stability at physiological pH. Molecular receptor targeting of this nanophytomedicine against folate receptor over-expressing cancers was demonstrated in vitro by conjugation with a potential cancer targeting ligand, folic acid (FA). Fluorescence microscopy and flow cytometry data showed highly specific cellular uptake of FA conjugated NanoGSE on folate receptor positive cancer cells. Studies were also conducted to investigate the efficiency of targeted (FA conjugated) versus non-targeted (non-FA conjugated) nanoformulations in causing cancer cell death. The IC{sub 50} values were lowered by a factor of {approx} 3 for FA-NanoGSE compared to the free drug, indicating substantially enhanced bioavailability to the tumor cells, sparing the normal ones. Receptor targeting of FA-NanoGSE resulted in a significant increase in apoptotic index, which was also quantified by flow cytometry and fluorescence microscopy. This in vitro study provides a basis for the use of nanoparticle mediated delivery of anticancer nutraceuticals to enhance bioavailability and effectively target cancer by a &apos;green&apos; approach.

  7. Épocas de colheita e tratamento pré-germinativos para superação da dormência de sementes Mimosa caesalpiniifolia Benth.

    OpenAIRE

    Leal,Josivan Viana; Alves,Edna Ursulino; Bruno,Riselane de Lucena Alcântara; Pereira,Walter Esfrain; Alves,Anarlete Ursulino; Galindo,Evio Alves; Alves,Adriana Ursulino

    2008-01-01

    Este trabalho teve por objetivo avaliar a influência da época de colheita e de tratamentos pré-germinativos na germinação e vigor de sementes de Mimosa caesalpiniifolia Benth. (sabiá). Para tanto, realizou-se um experimento no Laboratório de Análise de Sementes do CCA-UFPB, em Areia, PB, em delineamento inteiramente ao acaso, com os tratamentos distribuídos em esquema fatorial 2 x 2 x 14, com os fatores ano de colheita (2002 e 2003), sementes dentro ou fora do craspédio e tratamentos pré-germ...

  8. Spectacular energy technology: Panorama-Sauna Holzweiler. KfW funds indoor swimming pools as &apos;process heat&apos;; Energetisch spektakulaer: Panorama-Sauna Holzweiler. KfW foerdert Schwimmbaeder als &apos;Prozesswaerme&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Meissner, Rolf

    2008-11-15

    The &apos;'Panorama-Sauna'&apos; at Grafschaft is a big indoor swimming pool and Sauna centre in a rural region not far from Cologne and Koblenz. The charm of this spectacular solar project is in its minimalism. Conventional solar thermal power systems, in contrast, tend to be complex and prone to failure. (orig.)

  9. SSI&apos;s review of SKB&apos;s RD and D programme 2001

    Energy Technology Data Exchange (ETDEWEB)

    Hedberg, Bjoern; Larsson, Carl-Magnus; Wiebert, Anders [and others

    2002-08-01

    In the report SSI&apos;s review of SKB&apos;s RD and D programme 2001 is presented. In the review SSI comments, among other things, the decision making process, the need for a strategy document, SKB&apos;s safety and system analysis and SKB&apos;s biosphere studies.

  10. Myxofibrosarcoma: prevalence and diagnostic value of the &apos;&apos;tail sign&apos;&apos; on magnetic resonance imaging

    Energy Technology Data Exchange (ETDEWEB)

    Lefkowitz, Robert A.; Landa, Jonathan; Hwang, Sinchun; Panicek, David M. [Memorial Sloan-Kettering Cancer Center, Department of Radiology, New York, NY (United States); Weill Medical College of Cornell University, New York, NY (United States); Zabor, Emily C.; Moskowitz, Chaya S. [Memorial Sloan-Kettering Cancer Center, Department of Epidemiology and Biostatistics, New York, NY (United States); Agaram, Narasimhan P. [Memorial Sloan-Kettering Cancer Center, Department of Pathology, New York, NY (United States)

    2013-06-15

    Myxofibrosarcoma frequently shows curvilinear extensions of high T2 signal that also enhance on magnetic resonance imaging; these &apos;'tails'&apos; represent fascial extension of tumor at histopathological examination. This study was performed to determine whether the tail sign is helpful in distinguishing myxofibrosarcoma from other myxoid-containing neoplasms. The study group consisted of 44 patients with pathologically proven myxofibrosarcoma; the control group consisted of 52 patients with a variety of other myxoid-predominant tumors. Three musculoskeletal radiologists independently evaluated T2-weighted (and/or short-tau inversion recovery) and post-contrast MR images for the presence of one or more enhancing, high-signal intensity, curvilinear projections from the primary mass. Sensitivity and specificity for the diagnosis of myxofibrosarcoma were calculated for each reader. Interobserver variability was assessed with kappa statistic and percentage agreement. A tail sign was deemed present in 28, 30, and 34 cases of myxofibrosarcoma and in 11, 9, and 5 of the controls for the three readers respectively, yielding a sensitivity of 64-77 % and a specificity of 79-90 %. The interobserver agreement was moderate-to-substantial (kappa = 0.626). The tail sign at MRI is a moderately specific and sensitive sign for the diagnosis of myxofibrosarcoma relative to other myxoid-containing tumors. (orig.)

  11. Mapping of ApoE4 related white matter damage using diffusion MRI

    Science.gov (United States)

    Tsao, Sinchai; Gajawelli, Niharika; Hwang, Darryl H.; Kriger, Stephen; Law, Meng; Chui, Helena; Weiner, Michael; Lepore, Natasha

    2014-04-01

    ApoliopoproteinE Ɛ4 (ApoE-Ɛ4) polymorphism is the most well known genetic risk factor for developing Alzheimers Disease. The exact mechanism through which ApoE 4 increases AD risk is not fully known, but may be related to decreased clearance and increased oligomerization of Aβ. By making measurements of white matter integrity via diffusion MR and correlating the metrics in a voxel-based statistical analysis with ApoE-Ɛ4 genotype (whilst controlling for vascular risk factor, gender, cognitive status and age) we are able to identify changes in white matter associated with carrying an ApoE Ɛ4 allele. We found potentially significant regions (Puncorrected cognitive decline via a pathway in dependent of normal aging and acute insults that can be measured by CDR and Framingham Coronary Risk Score (FCRS).

  12. 1{sup st} annual workshop proceedings of the collaborative project &apos;&apos;Fast/instant release of safety relevant radionuclides from spent nuclear fuel&apos;&apos; (7{sup th} EC FP CP FIRST-Nuclides)

    Energy Technology Data Exchange (ETDEWEB)

    Kienzler, Bernhard; Metz, Volker; Duro, Lara; Valls, Alba (eds.)

    2013-07-01

    The EURATOM FP7 Collaborative Project &apos;&apos;Fast / Instant Release of Safety Relevant Radionuclides from Spent Nuclear Fuel (CP FIRST-Nuclides)&apos;&apos; started in January 1, 2012 and extends over 3 years. The European nuclear waste management organisations contributing to the Technology Platform &apos;&apos;Implementing Geological Disposal (IGD-TP)&apos;&apos; considered the fast / instant release of safety relevant radionuclides from high burn-up spent nuclear fuel as one of the key topics in the deployment plan. For this reason, the CP FIRST-Nuclides deals with understanding the behaviour of high burn-up uranium oxide (UO{sub 2}) spent nuclear fuels in deep geological repositories. The fast / instant release of radionuclides from spent nuclear fuel was investigated in a series of previous European. In addition, there were several studies mainly of the French research programs that investigated and quantified the rapid. However, several important issues are still open and consequently, the CP FIRST-Nuclides aims on covering this deficiency of knowledge, determining, for example, the &apos;&apos;instant release fraction (IRF)&apos;&apos; values of iodine, chlorine, carbon and selenium that are still largely unknown. Fuel elements from different Light Water Reactors (LWRs), with different enrichments, burn-up and average power rates need to be disposed of in Europe. This waste type represents one of the sources for the release of radionuclides after loss of integrity of a disposed canister. The quantification of time dependent release of radionuclides from spent high burn-up UO{sub 2} fuel is required for safety analyses. The first release fraction consists of radionuclides in gaseous form, and those showing a high solubility in groundwater. LWRs use conventional oxide fuels with initial enrichments of up to 5 wt.% {sup 235}U for reaching average burn-up of ≤ 60 GWd/t{sub HM}. During the use of UO{sub 2} in a reactor, a significantly higher burn-up takes

  13. A supramolecular &apos;'Double-cable'&apos; structure with a 129{sub 44} helix in a columnar porphyrin-C{sub 60} dyad and its application in polymer solar cells

    Energy Technology Data Exchange (ETDEWEB)

    Wang, Chien-Lung [College of Polymer Science and Polymer Engineering, The University of Akron, Akron, OH (United States); Department of Applied Chemistry, National Chiao Tung University, Hsinchu, Taiwan (China); Zhang, Wen-Bin; Sun, Hao-Jan; Van Horn, Ryan M.; Kulkarni, Rahul R.; Tsai, Chi-Chun; Gong, Xiong; Cheng, Stephen Z.D. [College of Polymer Science and Polymer Engineering, The University of Akron, Akron, OH (United States); Hsu, Chain-Shu [Department of Applied Chemistry, National Chiao Tung University, Hsinchu, Taiwan (China); Lotz, Bernard [Institut Charles Sadron, Strasbourg (France)

    2012-11-15

    A novel porphyrin-C{sub 60} dyad (PCD1) is designed and synthesized to investigate and manipulate the supramolecular structure where geometrically isotropic [such as [60]fullerene (C{sub 60})] and anisotropic [such as porphyrin (Por)] units coexist. It is observed that PCD1 possesses an enantiomeric phase behavior. The melting temperature of the stable PCD1 thermotropic phase is 160 C with a latent heat ({Delta}H) of 18.5 kJ mol{sup -1}. The phase formation is majorly driven by the cooperative intermolecular Por-Por and C{sub 60}-C{sub 60} interactions. Structural analysis reveals that this stable phase possesses a supramolecular &apos;'double-cable'&apos; structure with one p-type Por core columnar channel and three helical n-type C{sub 60} peripheral channels. These &apos;'double-cable'&apos; columns further pack into a hexagonal lattice with a = b = 4.65 nm, c = 41.3 nm, {alpha} = {beta} = 90 , and {gamma} = 120 . The column repeat unit is determined to possess a 129{sub 44} helix. With both donor (D; Pro) and acceptor (A; C{sub 60}) units having their own connecting channels as well as the large D/A interface within the supramolecular &apos;'double-cable'&apos; structure, PCD1 has photogenerated carriers with longer lifetimes compared to the conventional electron acceptor [6,6]-phenyl-C{sub 61}-butyric acid methyl ester. A phase-separated columnar morphology is observed in a bulk-heterojunction (BHJ) material made by the physical blend of a low band-gap conjugated polymer, poly[2,6-(4,4-bis-(2-ethylhexyl)-4H-cyclopenta [2,1-b;3,4-b&apos;]-dithiophene)-alt-4,7-(2,1,3-benzothia-diazole)] (PCPDTBT), and PCD1. With a specific phase structure in the solid state and in the blend, PCD1 is shown to be a promising candidate as a new electron acceptor in high performance BHJ polymer solar cells. (Copyright copyright 2012 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  14. Laplace&apos;s equation and Faraday&apos;s lines of force

    Energy Technology Data Exchange (ETDEWEB)

    Narasimhan, T.N.

    2007-06-01

    Boundary-value problems involve two dependent variables: a potential function, and a stream function. They can be approached in two mutually independent ways. The first, introduced by Laplace, involves spatial gradients at a point. Inspired by Faraday, Maxwell introduced the other, visualizing the flow domain as a collection of flow tubes and isopotential surfaces. Boundary-value problems intrinsically entail coupled treatment (or, equivalently, optimization) of potential and stream functions Historically, potential theory avoided the cumbersome optimization task through ingenious techniques such as conformal mapping and Green&apos;s functions. Laplace&apos;s point-based approach, and Maxwell&apos;s global approach, each provides its own unique insights into boundary-value problems. Commonly, Laplace&apos;s equation is solved either algebraically, or with approximate numerical methods. Maxwell&apos;s geometry-based approach opens up novel possibilities of direct optimization, providing an independent logical basis for numerical models, rather than treating them as approximate solvers of the differential equation. Whereas points, gradients, and Darcy&apos;s law are central to posing problems on the basis of Laplace&apos;s approach, flow tubes, potential differences, and the mathematical form of Ohm&apos;s law are central to posing them in natural coordinates oriented along flow paths. Besides being of philosophical interest, optimization algorithms can provide advantages that complement the power of classical numerical models. In the spirit of Maxwell, who eloquently spoke for a balance between abstract mathematical symbolism and observable attributes of concrete objects, this paper is an examination of the central ideas of the two approaches, and a reflection on how Maxwell&apos;s integral visualization may be practically put to use in a world of digital computers.

  15. Análise do custo do tratamento da ambliopia para o paciente em hospital universitário

    OpenAIRE

    Almeida,Luciana Ottaiano Cerântola de

    2005-01-01

    OBJETIVO: Avaliar os custos do tratamento da ambliopia para o paciente pela oclusão do olho dominante, assim como seu resultado visual. MÉTODOS: Realizou-se estudo prospectivo para avaliar o custo do tratamento de ambliopia por oclusão no Setor de Estrabismo do Hospital São Paulo - Universidade Federal de São Paulo/Escola Paulista de Medicina. Crianças portadoras de ambliopia entre 3 e 7 anos de idade foram incluídas no estudo. Os pacientes foram acompanhados a partir do diagnóstico até três ...

  16. Realidade virtual aplicada ao tratamento da ansiedade social

    OpenAIRE

    Pinheiro, Tânia Cristina Martins

    2012-01-01

    Trabalho de projecto de mestrado em Engenharia Informática (Engenharia de Software), apresentado à Universidade de Lisboa, através da Faculdade de Ciências, 2012 A ansiedade social é uma patologia debilitante que prejudica e diminui a qualidade de vida. O tratamento existe e ´e composto por várias terapias realizadas em simultâneo, sendo uma delas a terapia de exposição¸. Com a evolução tecnológica, surgiu a possibilidade de aplicar a Realidade Virtual `a terapia de exposição¸ (Terapia de ...

  17. A New Rose of Sharon Cultivar, &apos;Seonnyo&apos; Developed by Mutation Breeding

    International Nuclear Information System (INIS)

    Song, H.S.; Lim, Y.T.; Kim, J.K.; Park, I.S.; Kang, S.Y.; Kim, D.S.; Lee, S.J.

    2005-01-01

    &apos;Seonnyo&apos; is a new Hibiscus variety developed by mutation breeding using gamma ray irradiation at Korea Atomic Energy Research Institute (KAERI). One hundred seeds of original variety, &apos;Gyewolhyang&apos;, collected in Namyangju of Gyeonggi Province were irradiated 10 Krad a-ray from a ∨60Co source at KAERI in 1993 (Fig. 1). The original variety, &apos;Gyewolhyang&apos; showed the I-c that means single and bell-shaped flower type, and light purple with small red eye in its flower color. The irradiated seeds were sown in a field of the Atomic Experiment Farm in Namyangju, in April 1994. Forty-four out of one hundred seeds survived

  18. A New Rose of Sharon Variety, &apos;Changhae&apos; Developed by A Mutation Breeding

    International Nuclear Information System (INIS)

    Song, H.S.; Park, I.S.; Lim, Y.T.; Kim, J.K.; Lee, G.J.; Kim, D.S.; Kim, J.B.; Kang, S.Y.

    2006-01-01

    &apos;Changhae&apos; is a new Hibiscus variety developed by a mutation breeding by using a gamma ray irradiation. One hundred seeds of the original variety, &apos;Suminokura&apos;, grown in a breeding field in the Namyangju, Gyeonggi Province were irradiated with a 100 Gy gamma ray from a ∨60Co source at the Korea Atomic Energy Research Institute in 1993 (Fig. 1). The original variety, &apos;Suminokura&apos; belonged to the I-b category represented by a single flower, with an intermediate ratio of petal length/petal width, and a red purple color with a red-eye in the center of it&apos;s flower

  19. Tratamento cirúrgico postergado da pancreatite aguda biliar

    Directory of Open Access Journals (Sweden)

    Rodrigo Altenfelder Silva

    Full Text Available A análise do tratamento cirúrgico de doentes portadores de pancreatite biliar mostra a existência de controvérsias em relação à oportunidade da intervenção, principalmente se deve ser precoce ou postergada. Do mesmo modo, a possibilidade do emprego de procedimentos endoscópicos no pré, intra ou pós-operatório e o advento da videolaparoscopia, trouxeram novos aspectos à discussão. Não existe consenso sobre a escolha da melhor conduta. Em função disso, analisamos retrospectivamente os resultados imediatos de 107 doentes portadores de forma leve de pancreatite, todos com menos de três sinais de gravidade, segundo o critério de estratificação proposto por Ranson, e que foram submetidos ao tratamento cirúrgico postergado na mesma internação, no período de janeiro de 1988 a maio de 1999, tanto por via convencional como por via laparoscópica. Desses, 80 doentes (75% eram do sexo feminino, 90% da raça branca e a média de idade foi de 46 anos. Os doentes foram operados em média após 9,5 dias de internação e receberam alta hospitalar após 2,9 dias, o que resultou numa permanência hospitalar média de 12,6 dias. A colangiografia intra-operatória foi realizada em 102 casos (96% e a colangiografia endoscópica pré-operatória em 24 doentes (22,4%. Os resultados mostraram incidência de coledocolitíase em 25 casos (23%, taxa de morbidade de 12% e mortalidade nula. Dos 107 casos estudados, 64 (60% foram operados pela via de acesso convencional e 43 (40% pela via laparoscópica. A comparação dos resultados entre as vias de acesso empregadas mostrou diferença estatística significante em relação ao intervalo de tempo pós-operatório, que foi menor nos doentes submetidos à via de acesso laparoscópica. Concluímos, assim, que o tratamento cirúrgico postergado de doentes portadores de pancreatite biliar na forma leve apresenta baixas morbidade e mortalidade e pode ser feito tanto pela via convencional como pela via

  20. SOLAR MAGNETIZED &apos;TORNADOES&apos;: RELATION TO FILAMENTS

    Energy Technology Data Exchange (ETDEWEB)

    Su Yang; Veronig, Astrid; Temmer, Manuela [IGAM-Kanzelhoehe Observatory, Institute of Physics, University of Graz, Universitaetsplatz 5, A-8010 Graz (Austria); Wang Tongjiang [Department of Physics, Catholic University of America, Washington, DC 20064 (United States); Gan Weiqun, E-mail: yang.su@uni-graz.at [Key Laboratory of Dark Matter and Space Astronomy, Purple Mountain Observatory, Chinese Academy of Sciences, Nanjing 210008 (China)

    2012-09-10

    Solar magnetized &apos;tornadoes&apos;, a phenomenon discovered in the solar atmosphere, appear as tornado-like structures in the corona but are rooted in the photosphere. Like other solar phenomena, solar tornadoes are a feature of magnetized plasma and therefore differ distinctly from terrestrial tornadoes. Here we report the first analysis of solar &apos;tornadoes&apos; (two papers which focused on different aspects of solar tornadoes were published in the Astrophysical Journal Letters and Nature, respectively, during the revision of this Letter). A detailed case study of two events indicates that they are rotating vertical magnetic structures probably driven by underlying vortex flows in the photosphere. They usually exist as a group and are related to filaments/prominences, another important solar phenomenon whose formation and eruption are still mysteries. Solar tornadoes may play a distinct role in the supply of mass and twists to filaments. These findings could lead to a new explanation of filament formation and eruption.

  1. Tratamento físico-químico do caldo de cana produz cachaça de qualidade

    Directory of Open Access Journals (Sweden)

    Mara Lucia Dias Ribeiro

    Full Text Available RESUMO A cachaça é a aguardente produzida a partir da destilação do fermentado de caldo de cana. Atualmente destaca-se por ser a segunda bebida alcoólica mais consumida no Brasil e a terceira destilada no mundo. Diversos fatores afetam negativamente a cadeia produtiva, entre eles o tratamento do caldo e a levedura utilizada. Neste sentido, o objetivo do trabalho foi avaliar a influência do tipo de fermento e o tratamento do caldo sobre a qualidade do destilado. O experimento foi realizado na safra 2014/2015, utilizando-se a variedade SP83-2847. O delineamento experimental foi inteiramente casualizado com parcelas subdivididas, com 9 repetições. As parcelas foram constituídas pelo modo de tratamento do caldo (caldo clarificado e não clarificado e as subparcelas os tipos de fermento (Natural e CA-11. Foram determinadas características químicas do mosto, como Sólidos Solúveis Totais (SST, Compostos Fenólicos Totais (CFT, Açúcares Redutores Totais (ART e Acidez Total. No processo fermentativo avaliou-se a viabilidade das células e brotos e o índice de brotamentos. No vinho determinou-se o SST, ARRT, pH, acidez total, teor alcoólico, glicerol e eficiência fermentativa. Determinou-se a composição das cachaças através da quantificação de aldeídos totais, ésteres totais, metanol, acroleína, carbamato de etila, furfural, acidez volátil e coeficiente de congêneres. Analisou-se ainda condutividade elétrica, turbidez e pH, sendo os componentes secundários determinados por cromatografia gasosa. O tratamento prévio do caldo resultou em mosto de condições ideais para a levedura. A levedura CA-11 apresentou maiores teores de viabilidade celular. A associação entre tratamento de caldo e uso de fermento selecionado resulta em cachaça de composição mais equilibrada.

  2. Management of advanced prostate cancer Tratamento do câncer de próstata avançado

    Directory of Open Access Journals (Sweden)

    Rafael A. Kaliks

    2008-04-01

    Full Text Available Geriatricians and general practitioners often follow patients with metastatic prostate cancer. The epidemiology and basic treatment principles of metastatic prostate cancer are discussed aiming to update the topic for the non-oncologist. Hormone manipulation remains the basis of treatment, usually up to a second line of therapy. Selected cases are treated successfully with intermittent androgen ablation. When new hormone-independent clones arise, chemotherapy should be added to therapy that confers improved survival as well as better quality of life when based on taxanes. In specific situations, additional measures such as bisphosphonates and radiation therapy should be included in the treatment. As a rule, the public health system makes available the necessary medication to ensure treatment for the vast majority of patients in Brazil.Pacientes com câncer de prostata metastático estão freqüentemente sob os cuidados de geriatras e clínicos gerais. Discutimos a epidemiologia e os princípios básicos do tratamento do câncer de próstata metastático, visando atualizar o não-oncologista no assunto. A base do tratamento continua sendo a manipulação hormonal, inclusive como tratamento de segunda linha. Casos selecionados podem ser tratados com ablação androgênica intermitente de maneira eficaz. Quando se desenvolvem clones de células hormônio-independentes, quimioterápicos são incorporados na terapia. A quimioterapia confere não só benefício em sobrevida, mas também na qualidade de vida, quando baseado em taxanos. Medidas adicionais como o uso de bisfosfonados e radioterapia devem ser incorporadas no tratamento em situações especiais. De modo geral, o sistema público de saúde do Brasil disponibiliza todas as medicações necessárias ao adequado tratamento dos pacientes no país.

  3. &apos;&apos;Atomic Optics&apos;&apos;: Nonimaging Optics on the Nanoscale

    Energy Technology Data Exchange (ETDEWEB)

    Roland Winston Joseph O' Gallagher

    2005-01-15

    This is the final report for a one year close out extension of our basic research program that was established at the University of Chicago more than sixteen years ago to explore and develop the optical sub-discipline that has come to be known as &apos;&apos;nonimaging optics&apos;&apos;. This program has been extremely fruitful, having both broadened the range of formalism available for workers in this field and led to the discovery of many new families of optical devices. These devices and techniques have applications wherever the efficient transport and transformation of light distributions are important, in particular in illumination, fiber optics, collection and concentration of sunlight, and the detection of faint light signals in physics and astrophysics. Over the past thirty years, Nonimaging Optics (Welford and Winston, 1989) has brought a fresh approach to the analysis of many problems in classical macro-scale optics. Through the application of phase-space concepts, statistical methods, thermodynamic arguments, etc., many previously established performance limits were able to be broken and many technical surprises with exciting practical applications were discovered. The most recent three-year phase of our long-term continuing program ended in late 2002 and emphasized extending our work in geometrical optics and expanding it to include some interesting questions in physical optics as well as in the new field of statistical optics. This report presents a survey of the basic history and concepts of nonimaging optics and reviews highlights and significant accomplishments over the past fifteen years. This is followed by a more detailed summary of recent research directions and accomplishments during the last three years. This most recent phase was marked by the broadening in scope to include a separate project involving a collaboration with an industrial partner, Science Applications International Corporation (SAIC). This effort was proposed and approved in

  4. Obtaining &apos;images&apos; from iron objects using a 3-axis fluxgate magnetometer

    Energy Technology Data Exchange (ETDEWEB)

    Chilo, Jose [University of Gaevle, S-80176 Gaevle (Sweden); Jabor, Abbas [Royal Institute of Technology, Department of Physics, S-106 91 Stockholm (Sweden); Lizska, Ludwik [Swedish Institute of Space Physics in Umea (Sweden); Eide, Age J. [Ostfold University College, N-1757 Halden (Norway); Lindblad, Thomas [Royal Institute of Technology, Department of Physics, S-106 91 Stockholm (Sweden)], E-mail: lindblad@particle.kth.se

    2007-10-01

    Magnetic objects can cause local variations in the Earth&apos;s magnetic field that can be measured with a magnetometer. Here we used tri-axial magnetometer measurements and an analysis method employing wavelet techniques to determine the &apos;signature&apos; or &apos;fingerprint&apos; of different iron objects. Clear distinctions among the iron samples were observed. The time-dependent changes in the frequency powers were extracted by use of the Morlet wavelet corresponding to frequency bands from 0.1 to 100 Hz.

  5. ANÁLISE DA GERMINAÇÃO DE AROEIRA-PRETA (Myracrodruon urundeuva All. SUBMETIDA A DIFERENTES TRATAMENTOS DE QUEBRA DE DORMÊNCIA.

    Directory of Open Access Journals (Sweden)

    Flávio Henrique Ferreira Gomes

    2015-12-01

    Full Text Available O         trabalho teve por objetivo avaliar a influência de 6 tratamentos de quebra de dormência de sementes de Myracrodruon urundeuva All. determinando o índice germinativo.. As sementes foram submetidas a seis tipos de tratamentos experimentais, sendo: T1-Controle; T2-Imersão em água a temperatura ambiente (5 min; T3-Imersão em água à 70° C (5 min; T4-Imersão em água à 95° C (5 min; T5-Imersão em Hipoclorito de sódio à 1% (5 min; T6-Imersão em Ácido sulfúrico (15 min, em seguida condicionadas em casa de vegetação com sombrite 50 %. As sementes estiveram semeadas em tubetes com volume 240 cm³ e substrato, sendo mistura de areia e carvão vegetal na proporção de 8:2, cada tratamento conteve 25 sementes. As sementes foram irrigadas diariamente, pela manhã e ao final da tarde. O delineamento experimental utilizado foi em blocos ao acaso (DBC com 4 repetições.O parâmetro avaliado foi o de índice germinativo e as médias comparadas pelo teste de Tukey. Os resultados dos tratamentos envolvendo embebição em água a 70 °C e 95 °C e ácido sulfúrico não foram satisfatórios. Constatou-se que houve diferença significativa somente para o tratamento com hipoclorito de sódio (1 %, entretanto não foi possível avaliar qual tratamento seria melhor para superação de dormência de sementes de Myracrodruon urundeuva All.  já que os valores dos índices germinativos (%IG foram insignificantes.

  6. ENTRIA workshop: Emotions in the implementation of a final nuclear disposal site; ENTRIA-Werkstattgespraech: &apos;&apos;Emotionen bei der Realisierung eines Endlagers fuer Atommuell&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Kattau, Alke [Technische Univ. Braunschweig (Germany). Inst. fuer Rechtswissenschaften

    2016-08-15

    On 21 June 2016, prior to the publication of the report of the Commission Storage of High Radioactive Waste, &apos;&apos;Emotions in the realisation of a repository for nuclear waste&apos;&apos; were the topic of a workshop. The workshop was organised in the context of the Federal Ministry of Education and Research (BMBF) interdisciplinary research platform ENTRIA. In his opening remarks, Prof.Dr. Ulrich Smeddinck (Institute of Law of the University of Braunschweig) noticed, that emotions have been neglected in the scientific analysis so far, but fears and feelings to be considered with a special view.

  7. The &apos;mini brain&apos; appearance of plasmacytoma in the appendicular skeleton

    Energy Technology Data Exchange (ETDEWEB)

    Subhas, N.; Sundaram, M. [Cleveland Clinic, Department of Diagnostic Radiology, Cleveland, OH (United States); Bauer, T.W. [Cleveland Clinic, Department of Anatomic Pathology, Cleveland, OH (United States); Joyce, M.J. [Cleveland Clinic, Department of Orthopaedic Surgery, Cleveland, OH (United States)

    2008-08-15

    We report on the case of a 70-year-old woman presenting with right hip pain. Radiographs of the right hip demonstrated a well-defined large lytic lesion in the proximal right femur, with prominent trabeculae situated peripherally and extending into the lesion in a &apos;spoke-wheel&apos; pattern. Magnetic resonance imaging (MRI) demonstrated solid enhancing marrow-replacing lesion, with intervening linear nonenhancing areas of low T2 signal intensity. The MRI appearance resembled that of a small brain or &apos;mini brain&apos;. Biopsy specimen demonstrated predominantly mature plasma cells, with occasional admixed immature forms. A diagnosis of plasmacytosis, consistent with myeloma, was made. This case illustrates a rare but seemingly characteristic &apos;mini brain&apos; appearance of plasmacytoma, which, to date, has only been reported in the spine and has not been observed in other bony lesions. (orig.)

  8. Treatment of trigeminal neuralgia with low doses of topiramate Tratamento da neuralgia do trigêmeo com baixas doses de topiramato

    Directory of Open Access Journals (Sweden)

    Renan Barros Domingues

    2007-09-01

    Full Text Available Topiramate was administered to eight patients with classical trigeminal neuralgia with or without previous symptomatic therapy with other antiepileptic drugs. The topiramate doses ranged from 50 to 100 mg a day, according to the clinical response and the reported side effects. Three patients had complete symptoms remission, three reported moderate improvement, and the treatment was not effective in two. The most frequently registered side effects were dizziness, somnolence and weight loss. Topiramate can be considered an alternative treatment for patients with trigeminal neuralgia.Oito pacientes com neuralgia do trigêmeo, com ou sem tratamentos prévios com anticonvulsivantes, foram submetidos a tratamento com topiramato. As doses de topiramato variaram de 50 a 100 mg ao dia, de acordo com a resposta clínica e com os efeitos colaterais relatados. Três pacientes obtiveram remissão completa, três relataram melhora parcial e o tratamento com topiramato foi ineficaz em dois pacientes. Os efeitos colaterais mais frequentemente citados foram tontura, sonolência e perda de peso. O topiramato pode ser considerado uma alternativa potencialmente eficaz para o tratamento de pacientes com neuralgia do trigêmeo.

  9. Glymphatic distribution of CSF-derived apoE into brain is isoform specific and suppressed during sleep deprivation.

    Science.gov (United States)

    Achariyar, Thiyagaragan M; Li, Baoman; Peng, Weiguo; Verghese, Philip B; Shi, Yang; McConnell, Evan; Benraiss, Abdellatif; Kasper, Tristan; Song, Wei; Takano, Takahiro; Holtzman, David M; Nedergaard, Maiken; Deane, Rashid

    2016-12-08

    Apolipoprotein E (apoE) is a major carrier of cholesterol and essential for synaptic plasticity. In brain, it's expressed by many cells but highly expressed by the choroid plexus and the predominant apolipoprotein in cerebrospinal fluid (CSF). The role of apoE in the CSF is unclear. Recently, the glymphatic system was described as a clearance system whereby CSF and ISF (interstitial fluid) is exchanged via the peri-arterial space and convective flow of ISF clearance is mediated by aquaporin 4 (AQP4), a water channel. We reasoned that this system also serves to distribute essential molecules in CSF into brain. The aim was to establish whether apoE in CSF, secreted by the choroid plexus, is distributed into brain, and whether this distribution pattern was altered by sleep deprivation. We used fluorescently labeled lipidated apoE isoforms, lenti-apoE3 delivered to the choroid plexus, immunohistochemistry to map apoE brain distribution, immunolabeled cells and proteins in brain, Western blot analysis and ELISA to determine apoE levels and radiolabeled molecules to quantify CSF inflow into brain and brain clearance in mice. Data were statistically analyzed using ANOVA or Student's t- test. We show that the glymphatic fluid transporting system contributes to the delivery of choroid plexus/CSF-derived human apoE to neurons. CSF-delivered human apoE entered brain via the perivascular space of penetrating arteries and flows radially around arteries, but not veins, in an isoform specific manner (apoE2 > apoE3 > apoE4). Flow of apoE around arteries was facilitated by AQP4, a characteristic feature of the glymphatic system. ApoE3, delivered by lentivirus to the choroid plexus and ependymal layer but not to the parenchymal cells, was present in the CSF, penetrating arteries and neurons. The inflow of CSF, which contains apoE, into brain and its clearance from the interstitium were severely suppressed by sleep deprivation compared to the sleep state. Thus, choroid plexus

  10. Longitudinal Links between Fathers&apos; and Mothers&apos; Harsh Verbal Discipline and Adolescents&apos; Conduct Problems and Depressive Symptoms

    Science.gov (United States)

    Wang, Ming-Te; Kenny, Sarah

    2014-01-01

    This study used cross-lagged modeling to examine reciprocal relations between maternal and paternal harsh verbal discipline and adolescents&apos; conduct problems and depressive symptoms. Data were from a sample of 976 two-parent families and their children (51% males; 54% European American, 40% African American). Mothers&apos; and fathers&apos;…

  11. Linoleum: a &apos;green&apos; flooring option

    Energy Technology Data Exchange (ETDEWEB)

    Anon

    2002-07-01

    &apos;Green&apos; building materials may be defined as being made of materials and by processes that have low impact on the environment. Linoleum is an example of a sustainable &apos;green&apos; building material. It is durable, easy to repair, is inherently antimicrobial, and has low-cost maintenance. Unlike most other floor coverings, linoleum has naturally occurring anti-static properties, making it easy to clean, since dust and dirt will not adhere to it. The ingredients in linoleum are linseed oil, resin, limestone, wood flour, pigments and jute, all obtainable from natural sources. Vibrant colours for the flooring are created by using organic pigments with no heavy metals such as lead or calcium which, consequently, pose no threat to the environment. Linoleum is also biodegradable. It can be put into a landfill, where it will decompose; in some parts of the world it is incinerated to produce electricity. When used as feedstock for electricity, used linoleum products have an energy content of 18.6 MJ/kg, which is equivalent to coal. As no toxic or corrosive gases are released, the need for gas purification is avoided.

  12. Contribution to the evaluation of vortex-induced vibrations analysis using &apos;wake oscillators&apos; and &apos;vortex-tracking&apos; models; Contribuicao a avaliacao dos modelos &apos;wake oscillator&apos; e &apos;vortex tracking&apos; para analise de vibracoes induzidas por vortices

    Energy Technology Data Exchange (ETDEWEB)

    Carneiro, Daniel L. [Bureau Veritas do Brasil, Rio de Janeiro, RJ (Brazil); Ellwanger, Gilberto B. [Universidade Federal do Rio de Janeiro (UFRJ), Rio de Janeiro, RJ (Brazil). Coordenacao dos Programas de Pos-graduacao de Engenharia (COPPE); Galgoul, Nelson S. [SUPORTE Consultoria e Projetos, Rio de Janeiro, RJ (Brazil)

    2008-07-01

    Fatigue due to vortex-induced vibrations (VIV) is one of the major uncertainties today in the design of slender offshore structures, such as risers, pipelines, umbilicals, tendons and mooring lines, required for oil and gas production in deep waters. The absence of reliable tools for quantitative analyses of this phenomenon is a technological barrier, which is being faced by several research groups, generating tens of thesis and articles every year. This paper presents VIV results achieved by the author, using &apos;wake oscillator&apos; and &apos;vortex tracking&apos; models, when researching for his M. Sc. dissertation. Time domain analyses were performed using a commercial software. First results describe the response of the evaluated models for two degrees-of-freedom rigid cylinders, which were compared to values prescribed in recognized recommended practices. Afterwards, VIV analyses results for a steel catenary 10-inch diameter riser in three dimensional current profiles were compared to measured values. The considered riser, installed in 910 m water depth offshore Brazil, is possibly the only monitored SCR with no VIV suppression devices in the world today. The results were considered satisfactory, despite some discrepancies. The authors expect the presented results to contribute in further studies on these models. (author)

  13. &apos;Mote&apos; networks; A nano SWAT team for the oilpatch

    Energy Technology Data Exchange (ETDEWEB)

    Ross, E.

    2004-05-01

    &apos;Motes&apos; are tiny sensor modules which make up wireless sensor networks for monitoring parameters such as energy use or temperature. Motes have the capacity for self-configuring a network, self-correct without downtime if there is an interruption in the connection, and for transferring information using the fastest and most reliable path in sending data to the control system via a gateway. Dust Incorporated, a technology company based in Berkeley, California, employs motes to communicate with each other in a self-healing, self-organizing way, and to do so at the lowest possible cost. At present, motes are used mainly in defence and industrial monitoring applications, however the company is exploring potential applications in the oilpatch in facilities that include pumping stations, pipelines, or remote areas, unattended for long periods of time. Application in perimeter security systems is also being explored. Key to the technology is the concept of mesh networks: i.e. instead of each mote having a single channel back to a backbone, the system has multiple paths, able to find another path if one route fails. In the oil and gas industry one of the most promising applications so far has been use as a &apos;rapid profiling kit&apos; in which the network could be used to augment rough measurements with measurements of a higher resolution. Another application contemplated is use of mote networks in monitoring the health of machines by &apos;listening for crunching or knocking&apos;. Low power requirement is the key to success in wireless systems; accordingly, Dust Corporation&apos;s objective is to perfect the timing and radio transmission rates to the point where the modules can operate for five to ten years on two &apos;AA&apos; batteries.

  14. Individual Differences in Children&apos;s and Parents&apos; Generic Language

    Science.gov (United States)

    Gelman, Susan A.; Ware, Elizabeth A.; Kleinberg, Felicia; Manczak, Erika M.; Stilwell, Sarah M.

    2014-01-01

    Generics ("&apos;Dogs&apos; bark") convey important information about categories and facilitate children&apos;s learning. Two studies with parents and their 2- or 4-year-old children (N = 104 dyads) examined whether individual differences in generic language use are as follows: (a) stable over time, contexts, and domains, and (b) linked…

  15. &apos;&apos;114&apos;&apos;-type nitrides LnAl(Si{sub 4-x}Al{sub x})N{sub 7}O{sub δ} with unusual [AlN{sub 6}] octahedral coordination

    Energy Technology Data Exchange (ETDEWEB)

    Huang, Saifang; Ouyang, Xin [School of Materials Science and Technology, China University of Geosciences, Beijing (China); Department of Chemical and Materials Engineering, University of Auckland (New Zealand); Huang, Zhaohui; Fang, Minghao; Liu, Yan-gai [School of Materials Science and Technology, China University of Geosciences, Beijing (China); Cao, Peng; Gao, Wei [Department of Chemical and Materials Engineering, University of Auckland (New Zealand); Zujovic, Zoran; Soehnel, Tilo [School of Chemical Sciences, University of Auckland (New Zealand); Price, Jason R. [Australian Synchrotron, Clayton, VIC (Australia); Avdeev, Maxim [Australian Centre for Neutron Scattering, Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW (Australia); Que, Meidan [School of Electronic and Information Engineering, Xi' an Jiaotong University (China); Suzuki, Furitsu; Kido, Tsuyoshi; Kaji, Hironori [Institute for Chemical Research, Kyoto University (Japan)

    2017-03-27

    Aluminum-nitrogen six-fold octahedral coordination, [AlN{sub 6}], is unusual and has only been seen in the high-pressure rocksalt-type aluminum nitride or some complex compounds. Herein we report novel nitrides LnAl(Si{sub 4-x}Al{sub x})N{sub 7}O{sub δ} (Ln=La, Sm), the first inorganic compounds with [AlN{sub 6}] coordination prepared via non-high-pressure synthesis. Structure refinements of neutron powder diffraction and single-crystal X-ray diffraction data show that these compounds crystallize in the hexagonal Swedenborgite structure type with P6{sub 3}mc symmetry where Ln and Al atoms locate in anticuboctahedral and octahedral interstitials, respectively, between the triangular and Kagome layers of [SiN{sub 4}] tetrahedra. Solid-state NMR data of high-purity La-114 powders confirm the unusual [AlN{sub 6}] coordination. These compounds are the first examples of the &apos;&apos;33-114&apos;&apos; sub-type in the &apos;&apos;114&apos;&apos; family. The additional site for over-stoichiometric oxygen in the structure of 114-type compounds was also identified. (copyright 2017 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim)

  16. Comportamento da parasitemia avaliada pelo método de Strout modificado em chagásicos agudos em tratamento

    Directory of Open Access Journals (Sweden)

    Cleudson Castro

    1988-12-01

    Full Text Available Em 18 pacientes com doença de Chagas aguda foi semiquantificada a parasitemia, pelo método de Strout modificado, antes e durante o tratamento. Antes da terapêutica a parasitemia variou entre 1 e 104 tripanossomos, e após o início do tratamento a parasitemia foi lida repetidamente com um intervalo, na maioria dos casos, entre dois e cinco dias, até a negativação. A dose inicial dos medicamentos foi de 10 a 15mg/kg/dia de Nifurtimox para sete pacientes, e 10 a 20mg/kg/dia de Benzonidazol para onze indivíduos. Após início do tratamento com Nifurtimox um paciente ficou o mínimo de cinco e dois o máximo de 23 dias com parasitemia enquanto com o Benzonidazol um paciente permaneceu o máximo de 15 dias.com parasitemia patente. O Benzonidazol baixou a parasitemia mais rapidamente que o Nifurtimox

  17. AVALIAÇÃO DA EFICIÊNCIA DE UM SISTEMA DE TRATAMENTO DA ÁGUA EM PEQUENA PROPRIEDADE RURAL, UTILIZANDO BIOENSAIOS

    Directory of Open Access Journals (Sweden)

    Geani Mohr

    2013-07-01

    Full Text Available O trabalho teve como objetivo avaliar a toxicidade aguda do efluente de um sistema de tratamento de água em pequena propriedade rural, utilizando Daphnia magna Straus como organismo-teste. Os processos empregados no tratamento foram: tratamento primário (reatores anaeróbios, tratamento secundário/terciário (Wetlands construídos - WC’s e tratamento final (sistema de desinfecção Ultra Violeta - UV. Entre os meses de dezembro e junho de 2012, foram coletadas 30 amostras de cinco fases distintas (Bruto - P1, Água da Chuva - P2, Reator anaeróbico de fluxo ascendente e manta de lodo (UASB - P3, WC’s-P4 e desinfecção com UV - P5. Os resultados indicaram toxicidade aguda em P1, com uma CE(I50% 48h de 25,8 ± 23,64% (n = 6; CV = 109,2%, correspondendo a uma amostra altamente tóxica. Nos pontos P2 e P3, as amostras apresentaram uma CE(I50% 48h de 5,1% ± 3,5% (n = 6; CV = 145,7% e 36,7 ± 23,9% (n = 6; CV = 153,5%, correspondendo a uma amostra extremamente tóxica e altamente tóxica, respectivamente. Os efluentes dos pontos P4 (n = 6 e P5 (n = 6 não apresentaram toxicidade. Desta forma, os resultados demonstraram a eficiência da capacidade de detoxificação dos processosWC’s e UV.

  18. Crisis - Weisskopf&apos;s view

    International Nuclear Information System (INIS)

    Anon.

    1993-01-01

    &apos;We are facing a crisis, not only in particle physics but in the whole of fundamental science&apos;, said Victor Weisskopf, doyen of quantum physics, during his traditional summer CERN stopover. &apos;Basic science - science for its own sake - and especially high energy physics, is really in danger.&apos; As well as explaining how this has come about, the former CERN Director General (1961-5) proposed action to reverse the trend. Rather than dividing science into the conventional &apos;big&apos; and &apos;small&apos; camps, he slices across another axis. On one hand there is obviously applicable &apos;terrestrial science&apos; - biology, medicine, solid state, much of the nuclear sector, nonlinear behaviour, chaos,....all directly connected with processes that happen on Earth. On the other there is &apos;cosmic science&apos; - astronomy, astrophysics, particle physics and some of the nuclear sector - addressing deeper issues, not attainable naturally on this planet at all, and where applications are less immediately obvious. (This classification is not completely watertight - even cosmic science can, and does, foster immediate spinoff, Weisskopf points out, citing Georges Charpak&apos;s detector work.) Tracing the evolution of science in this century, Weisskopf sees the rapid evolution of American influence in the 1930s as a turning point. Before then, the United States had not been in the front line, and it had been important for US researchers to spend some time in Europe

  19. Documentation to the workshop &apos;Cluster in the environmental protection economy&apos;; Dokumentation zum Workshop &apos;&apos;Cluster in der Umweltschutzwirtschaft&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    NONE

    2009-12-11

    Within the workshop &apos;Cluster in the environmental protection economy&apos; at the Umweltbundesamt (Dessau-Rosslau, Federal Republic of Germany) at 27th November, 2008, the following lectures were held: (a) Which contribution can cluster and cluster politics contribute to the promotion of the environmental protection economy? (Harald Legler); (b) Cluster in the environmental protection economy: Targets and expectations (Dieter Rehfeld); (c) Demands at the management of clusters (Karin Hoerhan); (d) Demands at the cluster politics in the environmental protection economy (Bernhard Hausberg); (e) Photovoltaics in Eastern Germany (Johann Wackenbauer); (f) Automotive industry in Bergisches Land (Thomas Lemken); (g) Competence centre environment Augsburg-Schwaben (Egon Beckord).

  20. The polarized neutron reflectometer &apos;Reverans&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Radzhabov, A.K. [Petersburg Nuclear Physics Institute, Gatchina, St. Petersburg 188300 (Russian Federation)]. E-mail: akr@pnpi.spb.ru; Gordeev, G.P. [Petersburg Nuclear Physics Institute, Gatchina, St. Petersburg 188300 (Russian Federation); Lazebnik, I.M. [Petersburg Nuclear Physics Institute, Gatchina, St. Petersburg 188300 (Russian Federation); Axelrod, L.A. [Petersburg Nuclear Physics Institute, Gatchina, St. Petersburg 188300 (Russian Federation); Zabenkin, V.N. [Petersburg Nuclear Physics Institute, Gatchina, St. Petersburg 188300 (Russian Federation)

    2007-07-15

    The polarized neutron reflectometer &apos;Reverans&apos; with a vertical plane of scattering is being installed at the VVR-M reactor (Gatchina, Russia). It will be used for research on phase boundaries, interfaces and free surfaces. Systems under study can be both magnetic and nonmagnetic ones. At present the installation of the reflectometer is at the final stage. The parameters and abilities of the reflectometer are presented.

  1. Das sangrias à penicilina: o saber médico e o tratamento da sífilis.

    OpenAIRE

    Geraldes Neto, Benedito

    2009-01-01

    atual conhecimento técnico sobre etiologia, formas de contágio, quadro clínico e tratamento da sífilis levou mais de quatro séculos para ser construído. O objetivo desta dissertação é identificar e discutir as mudanças ocorridas no saber médico sobre a doença ao longo desse tempo, particularmente com relação ao tratamento. Material e Métodos: Foi realizada pesquisa bibliográfica de natureza histórica, tendo como fontes principais os periódicos médicos das épocas estudadas. A pesquisa foi comp...

  2. Trimethylsilylcyclopentadienyl (cp{sup &apos;}) uranium chemistry. Synthetic and structural studies of Cp{sup &apos;}{sub 4}U and Cp{sup &apos;}{sub 3}UX (X = Cl, I, Me)

    Energy Technology Data Exchange (ETDEWEB)

    Windorff, Cory J.; MacDonald, Matthew R.; Ziller, Joseph W.; Evans, William J. [Department of Chemistry, University of California, Irvine, CA (United States)

    2017-12-13

    Cp{sup &apos;}{sub 4}U (Cp{sup &apos;} = C{sub 5}H{sub 4}SiMe{sub 3}) was synthesized from: (a) KCp{sup &apos;} and [Cp{sup &apos;}{sub 3}U(THF)][BPh{sub 4}]; (b) Cp{sup &apos;}{sub 3}U and Cp{sup &apos;}{sub 2}Pb; and (c) [K(2.2.2-cryptand)][Cp{sup &apos;}{sub 4}U] and AgBPh{sub 4}. The compound was identified by X-ray crystallography as a rare example of a structurally-characterized tetrakis(cyclopentadienyl)U{sup IV} complex. For comparison, the corresponding Th complex, Cp{sup &apos;}{sub 4}Th, was isolated from the direct combination of ThBr{sub 4}(THF){sub 4} with excess KCp{sup &apos;}. During the preparation of Cp{sup &apos;}{sub 3}UMe, the precursor of the [Cp{sup &apos;}{sub 3}U(THF)][BPh{sub 4}] reagent used above, it was discovered that the reaction of Cp{sup &apos;}{sub 3}UCl and MeLi gives a mixture of Cp{sup &apos;}{sub 3}UMe and Cp{sup &apos;}{sub 3}UCl that can co-crystallize better than Cp{sup &apos;}{sub 3}UMe in pure form. The Cp&apos;{sub 3}UMe/Cp{sup &apos;}{sub 3}UCl mixture forms single crystals suitable for X-ray crystallography and provides a new way to characterize the oil, Cp{sup &apos;}{sub 3}UMe. Cp{sup &apos;}{sub 3}UCl and Cp{sup &apos;}{sub 3}UI were also crystallographically characterized for comparison with the Cp{sup &apos;}{sub 3}UMe/Cp{sup &apos;}{sub 3}UCl crystals. (copyright 2017 WILEY-VCH Verlag GmbH and Co. KGaA, Weinheim)

  3. The &apos;2000-Watt per person&apos;- industrial society - Utopia, vision or necessity?; Die &apos;2000 Watt pro Kopf&apos;-Industriegesellschaft - Utopie, Vision oder Notwendigkeit?

    Energy Technology Data Exchange (ETDEWEB)

    Jochem, E

    2006-07-01

    This short article takes a look at the &apos;2000-Watt per person&apos; concept initially developed at the Swiss Federal Institute of Technology (ETH) in Zurich, Switzerland, in 1998. The author is of the opinion that the concept is not utopian but a vision that can be realised - providing it is accepted socially and that politics can implement it. Further work on the concept done at the ETH over the years is listed and commented on. A diagram provides an overview of energy resources, energy transformation and energy flows to final energy consumption. The question as to if the realisation of such a &apos;2000-Watt&apos;-society is actually necessary is posed.

  4. The adductor magnus &apos;'mini-hamstring'&apos;: MRI appearance and potential pitfalls

    International Nuclear Information System (INIS)

    Broski, Stephen M.; Murthy, Naveen S.; Collins, Mark S.; Krych, Aaron J.; Obey, Mitchel R.

    2016-01-01

    To examine the anatomic MRI characteristics of the adductor magnus mini hamstring (AMMH) and explore its involvement in cases of hamstring avulsion. An IRB-approved retrospective review of patients undergoing &apos;&apos;hamstring protocol&apos;&apos; MRI between March 2009 and June 2014 was performed. Two musculoskeletal radiologists recorded multiple AMMH anatomic characteristics and involvement in cases of hamstring avulsion. Seventy-six AMMHs were analyzed in 66 patients [35 females and 31 males, mean age 49.3 ± 15.2 years (range 17-81)]. Eleven percent of AMMHs were poorly visualized, 51 % visualized, and 37 % well visualized. Seven percent demonstrated round, 73 % ovoid, and 21 % flat/lenticular tendon morphologies. Most (88 %) demonstrated typical origins. Average cross-sectional area (CSA) was 22.4 ± 10.6 mm 2 (range 6-56), diameter was 7.2 ± 2.5 mm (range 2.9-15), medial distance from the semimembranosus tendon was 7.5 ± 2.5 mm (range 3-14), and tendon length was 6.8 ± 3.3 cm (range 1.2-14.1). There was no gender difference in AMMH anatomic measurements or correlation between age and CSA or diameter. Of 17 complete hamstring avulsion cases, the AMMH was intact in 13, partially torn in 3, and completely torn in 1. The AMMH is a constant finding with variable anatomic characteristics. It is visualized or well visualized by MRI in 88 % of cases and is a sizable tendon located in close proximity to the semimembranosus tendon. Because it is uncommonly completely torn (6 %) in cases of complete hamstring avulsion, radiologists should be aware of its presence and appearance to avoid diagnostic confusion. (orig.)

  5. The trochlear cleft: the &apos;&apos;black line&apos;&apos; of the trochlear trough

    Energy Technology Data Exchange (ETDEWEB)

    Wissman, Robert D.; Nepute, Joshua; Fischer, Nathaniel von; Radhakrishnan, Rupa; Hendry, Daniel [University of Cincinnati Medical Center, Department of Radiology, Cincinnati, OH (United States); Ingalls, Jerrell [Desert Radiologists, Las Vegas, NV (United States); Kenter, Keith [University of Cincinnati Medical Center, Department of Orthopaedic Surgery, Cincinnati, OH (United States)

    2012-09-15

    The &apos;&apos;cartilage black line sign&apos;&apos; is a recently described T2 dark cartilage lesion that we have identified appearing as a cleft in the trochlear trough. The purpose of our study was to define the MR imaging characteristics of a trochlear cleft, determine its incidence, and correlate the MR findings with arthroscopy. A total of 1,300 consecutive MR examinations of the knee were retrospectively reviewed by consensus of two fellowship-trained musculoskeletal radiologists. The MR imaging characteristics and location of a trochlear cleft were determined. Imaging results were compared to arthroscopy when available. Patient age and gender were compared to 25 randomly selected control patients without trochlear clefts. A total of 25 (1.9%) individuals (11 females and 14 males; age range 19-45 years; mean age 28 years) were diagnosed with a trochlear cleft. The control group consisted of 11 females and 14 males; age range 19-83 years; mean age 46 years. Mean cleft length was 7 mm (range 6-12 mm); cleft location was consistently in the lower trochlear trough. No full-thickness cartilage defects were identified in the eight individuals in whom arthroscopic correlation was available. A grade 2 cartilage lesion was identified in a single individual; another progressed from grade 0 to a full-thickness trochlear lesion over an 8-month interval. Eight individuals were athletes. No significant difference in gender was noted between the two groups, however, the study group was significantly younger p < 0.0001. A trochlear cleft is a rare finding in young active individuals. It most likely indicates an incomplete cartilage fissure which may rarely progress to a full-thickness defect. (orig.)

  6. The adductor magnus &apos;'mini-hamstring'&apos;: MRI appearance and potential pitfalls

    Energy Technology Data Exchange (ETDEWEB)

    Broski, Stephen M.; Murthy, Naveen S.; Collins, Mark S. [Department of Radiology, Mayo Clinic, Rochester, MN (United States); Krych, Aaron J. [Department of Orthopedic Surgery, Mayo Clinic, Rochester, MN (United States); Obey, Mitchel R. [Mayo School of Graduate Medical Education, Rochester, MN (United States)

    2016-02-15

    To examine the anatomic MRI characteristics of the adductor magnus mini hamstring (AMMH) and explore its involvement in cases of hamstring avulsion. An IRB-approved retrospective review of patients undergoing &apos;&apos;hamstring protocol&apos;&apos; MRI between March 2009 and June 2014 was performed. Two musculoskeletal radiologists recorded multiple AMMH anatomic characteristics and involvement in cases of hamstring avulsion. Seventy-six AMMHs were analyzed in 66 patients [35 females and 31 males, mean age 49.3 ± 15.2 years (range 17-81)]. Eleven percent of AMMHs were poorly visualized, 51 % visualized, and 37 % well visualized. Seven percent demonstrated round, 73 % ovoid, and 21 % flat/lenticular tendon morphologies. Most (88 %) demonstrated typical origins. Average cross-sectional area (CSA) was 22.4 ± 10.6 mm{sup 2} (range 6-56), diameter was 7.2 ± 2.5 mm (range 2.9-15), medial distance from the semimembranosus tendon was 7.5 ± 2.5 mm (range 3-14), and tendon length was 6.8 ± 3.3 cm (range 1.2-14.1). There was no gender difference in AMMH anatomic measurements or correlation between age and CSA or diameter. Of 17 complete hamstring avulsion cases, the AMMH was intact in 13, partially torn in 3, and completely torn in 1. The AMMH is a constant finding with variable anatomic characteristics. It is visualized or well visualized by MRI in 88 % of cases and is a sizable tendon located in close proximity to the semimembranosus tendon. Because it is uncommonly completely torn (6 %) in cases of complete hamstring avulsion, radiologists should be aware of its presence and appearance to avoid diagnostic confusion. (orig.)

  7. Boron neutron capture therapy (BNCT) translational studies in the hamster cheek pouch model of oral cancer at the new &apos;&apos;B2&apos;&apos; configuration of the RA-6 nuclear reactor

    International Nuclear Information System (INIS)

    Monti Hughes, Andrea; Trivillin, Veronica A.; Schwint, Amanda E.; Longhino, Juan; Boggio, Esteban; Medina, Vanina A.; Martinel Lamas, Diego J.; Garabalino, Marcela A.; Heber, Elisa M.; Pozzi, Emiliano C.C.; Itoiz, Maria E.; Aromando, Romina F.; Nigg, David W.

    2017-01-01

    Boron neutron capture therapy (BNCT) is based on selective accumulation of B-10 carriers in tumor followed by neutron irradiation. We demonstrated, in 2001, the therapeutic effect of BNCT mediated by BPA (boronophenylalanine) in the hamster cheek pouch model of oral cancer, at the RA-6 nuclear reactor. Between 2007 and 2011, the RA-6 was upgraded, leading to an improvement in the performance of the BNCT beam (B2 configuration). Our aim was to evaluate BPA-BNCT radiotoxicity and tumor control in the hamster cheek pouch model of oral cancer at the new &apos;&apos;B2&apos;&apos; configuration. We also evaluated, for the first time in the oral cancer model, the radioprotective effect of histamine against mucositis in precancerous tissue as the dose-limiting tissue. Cancerized pouches were exposed to: BPA-BNCT; BPA-BNCT + histamine; BO: Beam only; BO + histamine; CONTROL: cancerized, no-treatment. BNCT induced severe mucositis, with an incidence that was slightly higher than in &apos;&apos;B1&apos;&apos; experiments (86 vs 67%, respectively). BO induced low/moderate mucositis. Histamine slightly reduced the incidence of severe mucositis induced by BPA-BNCT (75 vs 86%) and prevented mucositis altogether in BO animals. Tumor overall response was significantly higher in BNCT (94-96%) than in control (16%) and BO groups (9-38%), and did not differ significantly from the &apos;&apos;B1&apos;&apos; results (91%). Histamine did not compromise BNCT therapeutic efficacy. BNCT radiotoxicity and therapeutic effect at the B1 and B2 configurations of RA-6 were consistent. Histamine slightly reduced mucositis in precancerous tissue even in this overly aggressive oral cancer model, without compromising tumor control. (orig.)

  8. Boron neutron capture therapy (BNCT) translational studies in the hamster cheek pouch model of oral cancer at the new &apos;&apos;B2&apos;&apos; configuration of the RA-6 nuclear reactor

    Energy Technology Data Exchange (ETDEWEB)

    Monti Hughes, Andrea; Trivillin, Veronica A.; Schwint, Amanda E. [Constituyentes Atomic Center, National Atomic Energy Commission (CNEA), Department of Radiobiology, San Martin, Province Buenos Aires (Argentina); National Research Council (CONICET), Ciudad Autonoma de Buenos Aires (Argentina); Longhino, Juan; Boggio, Esteban [Bariloche Atomic Center, CNEA, Department of Nuclear Engineering, San Carlos de Bariloche, Province Rio Negro (Argentina); Medina, Vanina A.; Martinel Lamas, Diego J. [National Research Council (CONICET), Ciudad Autonoma de Buenos Aires (Argentina); Pontifical Catholic University of Argentina (UCA), Laboratory of Tumoral Biology and Inflammation, School of Medical Sciences, Institute for Biomedical Research (BIOMED CONICET-UCA), Ciudad Autonoma de Buenos Aires (Argentina); Garabalino, Marcela A.; Heber, Elisa M.; Pozzi, Emiliano C.C. [Constituyentes Atomic Center, National Atomic Energy Commission (CNEA), Department of Radiobiology, San Martin, Province Buenos Aires (Argentina); Itoiz, Maria E. [Constituyentes Atomic Center, National Atomic Energy Commission (CNEA), Department of Radiobiology, San Martin, Province Buenos Aires (Argentina); UBA, Department of Oral Pathology, Faculty of Dentistry, Ciudad Autonoma de Buenos Aires (Argentina); Aromando, Romina F. [UBA, Department of Oral Pathology, Faculty of Dentistry, Ciudad Autonoma de Buenos Aires (Argentina); Nigg, David W. [Idaho National Laboratory, Idaho Falls (United States)

    2017-11-15

    Boron neutron capture therapy (BNCT) is based on selective accumulation of B-10 carriers in tumor followed by neutron irradiation. We demonstrated, in 2001, the therapeutic effect of BNCT mediated by BPA (boronophenylalanine) in the hamster cheek pouch model of oral cancer, at the RA-6 nuclear reactor. Between 2007 and 2011, the RA-6 was upgraded, leading to an improvement in the performance of the BNCT beam (B2 configuration). Our aim was to evaluate BPA-BNCT radiotoxicity and tumor control in the hamster cheek pouch model of oral cancer at the new &apos;&apos;B2&apos;&apos; configuration. We also evaluated, for the first time in the oral cancer model, the radioprotective effect of histamine against mucositis in precancerous tissue as the dose-limiting tissue. Cancerized pouches were exposed to: BPA-BNCT; BPA-BNCT + histamine; BO: Beam only; BO + histamine; CONTROL: cancerized, no-treatment. BNCT induced severe mucositis, with an incidence that was slightly higher than in &apos;&apos;B1&apos;&apos; experiments (86 vs 67%, respectively). BO induced low/moderate mucositis. Histamine slightly reduced the incidence of severe mucositis induced by BPA-BNCT (75 vs 86%) and prevented mucositis altogether in BO animals. Tumor overall response was significantly higher in BNCT (94-96%) than in control (16%) and BO groups (9-38%), and did not differ significantly from the &apos;&apos;B1&apos;&apos; results (91%). Histamine did not compromise BNCT therapeutic efficacy. BNCT radiotoxicity and therapeutic effect at the B1 and B2 configurations of RA-6 were consistent. Histamine slightly reduced mucositis in precancerous tissue even in this overly aggressive oral cancer model, without compromising tumor control. (orig.)

  9. Education and training for industry: share initiatives and best practices. Challenges for EURATOM research and training in the frame of the European &apos;Higher Education&apos; and &apos;Research&apos; areas

    Energy Technology Data Exchange (ETDEWEB)

    Van Goethem, Georges [European Commission, DG RTD, Energy - Euratom, Brussels (Belgium)

    2008-07-01

    For the sake of clarification, education and training (E and T) are defined as follows: - Education is a basic or life-long learning process: education is broader than training and encompasses the need to maintain completeness and continuity of competences across generations (it is essentially a knowledge-driven process, involving academic institutions as suppliers, and students as customers). - Training is learning a particular skill required to deliver a particular outcome: training is about schooling activities other than regular academic education schemes (it is essentially an application-driven process, involving industrial/regulatory training organisations as suppliers, and professionals as customers). The goal of the EURATOM education programmes is, in collaboration with academia, to offer instruments that help produce top-quality teaching modules that can be assembled into higher level training packages or Masters programmes that are jointly qualified and mutually recognised across the EU. This is done naturally in line with the Bologna process (ERASMUS). The following four objectives have been agreed upon (ENEN): - Modular courses and common qualification approach (offer a coherent E and T framework and ensure top-quality for each module); - One mutual recognition system across the European Union (e.g. European Credit Transfer and accumulation System of ERASMUS /ECTS/); - Mobility for teachers and students across the EU (prepare the &apos;internal market&apos; for free circulation of nuclear experts); - Feedback from &apos;stakeholders&apos; (Both scientific and financial). (involve the &apos;future employers&apos; in the process, thereby getting additional funding). The goal of the EURATOM training programmes is, in collaboration with &apos;future employers&apos;, to identify commonalties amongst CPD actions (&apos;Continuous Professional Development&apos;). The following four objectives have been agreed upon (&apos;EURATOM Fission Training Scheme&apos

  10. Fair Miles? The concept of &apos;food miles&apos; through a sustainable development lens

    Energy Technology Data Exchange (ETDEWEB)

    MacGregor, James; Vorley, Bill

    2006-10-15

    The concept of &apos;food miles&apos; presents an argument to buy goods which have travelled the shortest distance from farm to table, and to discriminate against long-haul transportation, especially air-freighted goods. The long-distance transport of food is associated with additional emissions due to increased transportation coupled with greater packaging, as well as a disconnection between the public and local farming. Furthermore, &apos;food miles&apos; encapsulates (and is at the vanguard of) the climate change debate in the UK. In light of growing international concern over the speed and scale of climate change, the concept of &apos;food miles&apos; has captured public attention and apparently is changing some consumers&apos; behaviour, although only around one-third of shoppers know of the concept.

  11. Assessment report of research and development activities FY2014. Activity: &apos;Advanced science research&apos; (Final report)

    International Nuclear Information System (INIS)

    2015-09-01

    Japan Atomic Energy Agency (hereinafter referred to as &apos;JAEA&apos;) consulted an assessment committee, &apos;Evaluation Committee of Research Activities for Advanced Science Research&apos; (hereinafter referred to as &apos;Committee&apos;) for final evaluation and prior assessment of &apos;Advanced Science Research,&apos; in accordance with &apos;General Guideline for the Evaluation of Government Research and Development (R and D) Activities&apos; by Cabinet Office, Government of Japan, &apos;Guideline for Evaluation of R and D in Ministry of Education, Culture, Sports, Science and Technology&apos; and &apos;Regulation on Conduct for Evaluation of R and D Activities&apos; by JAEA. In response to the JAEA&apos;s request, the Committee assessed the research programs and activities of the Advanced Science Research Center (hereinafter referred to as &apos;ASRC&apos;) for the period of five years from April 2010 and the research programs from April 2015. The Committee evaluated the management and the research programs of the ASRC based on the explanatory documents prepared by the ASRC and the oral presentations with questions-and-answers by the Director and the research group leaders. This report summarizes the results of the assessment by the Committee with the Committee report attached. (author)

  12. Synthesis, characterization and molecular structure of a dinuclear uranyl complex supported by N,N&apos;,N'',N''&apos;-tetra-(3,5-di-tert-butylsalicylidene)-1,2,4,5- phenylenetetraamine

    Energy Technology Data Exchange (ETDEWEB)

    Schnorr, Rene; Handke, Marcel; Kersting, Berthold [Leipzig Univ. (Germany). Inst. fuer Anorganische Chemie

    2015-07-01

    The preparation, characterization and the molecular structure of a dinuclear uranyl complex [(UO{sub 2}){sub 2}L(OCMe{sub 2}){sub 2}] supported by the bis-salophen ligand N,N&apos;,N'',N''&apos;-tetra-(3,5-di-tert-butylsalicylidene)-1,2,4,5- phenylenetetraamine (L{sup 4-}) is described. [(UO{sub 2}){sub 2}L(OCMe{sub 2}){sub 2}] was prepared by reaction of uranyl nitrate with the neutral, protonated form of the ligand (H{sub 4}L) in acetone. From a saturated acetone solution [(UO{sub 2}){sub 2}L(OCMe{sub 2}){sub 2}] . 1.5(OCMe{sub 2}) crystallizes triclinically, space group P anti 1 with a = 1522.7(2), b = 1751.4(2), c = 1815.4(2) Aa, α = 109.16(1), β = 99.29(1), γ = 105.29(1) and Z = 2. Each uranium atom is surrounded in a distorted pentagonal bipyramidal fashion by two O and two N atoms of the salicylidene units, one O atom of an acetone ligand, and the two oxo groups. The cyclic voltammogram of [(UO{sub 2}){sub 2}L(OCMe{sub 2}){sub 2}] shows two quasi-reversible redox processes centered at +0.57 V and +0.82 V vs. Fc{sup +}/Fc attributed to the sequential oxidation of the coordinating phenolates to phenoxyl radicals. The crystal structure of an ethanol solvate of H{sub 4}L was also determined by X-ray crystallography. H{sub 4}L . 5EtOH: triclinic, space group P anti 1, a = 1003.4(3), b = 1187.7(3), c = 1905.1(5) Aa, α = 75.75(2), β = 78.74(2), γ = 66.66(2) , Z = 1.

  13. Reflection group on &apos;Expert Culture&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Eggermont, G

    2000-07-01

    As part of SCK-CEN&apos;s social sciences and humanities programme, a reflection group on &apos;Expert Culture&apos; was established. The objectives of the reflection group are: (1) to clarify the role of SCK-CEN experts; (2) to clarify the new role of expertise in the evolving context of risk society; (3) to confront external views and internal SCK-CEN experiences on expert culture; (4) to improve trust building of experts and credibility of SCK-CEN as a nuclear actor in society; (5) to develop a draft for a deontological code; (6) to integrate the approach in training on assertivity and communication; (7) to create an output for a topical day on the subject of expert culture. The programme, achievements and perspectives of the refection group are summarised.

  14. A New Rose of Sharon Cultivar, &apos;Daegoang&apos; Developed by Mutation Breeding

    International Nuclear Information System (INIS)

    Song, H.S.; Kim, J.K.; Lim, Y.T.; Park, I.S.; Kang, S.Y.; Kim, D.S.; Lee, S.J.

    2005-01-01

    &apos;Daegoang&apos; is a new Hibiscus variety developed by mutation breeding using gamma ray irradiation at Korea Atomic Energy Research Institute (KAERI). One hundred seeds of original variety, &apos;Yongkwang&apos;, collected in Namyangju of Gyeonggi Province were irradiated 10 Krad γ-ray from a ∨60Co source at KAERI in 1994 (Fig. 1). The flower type and color of the variety &apos;Yongkwang&apos; was I-b that means single and fully open, and light purple with red eye, respectively. The irradiated seeds were sown in a field of the Atomic Experiment Farm in Namyangju, in April 1994. The survival rate of seedling at the 0 and 100 Gy dose was 50% and 35%, respectively (Table 1)

  15. Power supply - HVDC and facts make it sustainable and secure; Stromversorgung - nachhaltig und sicher mit HGUeund Facts. Grid Access fuer &apos;&apos;gruene Energie&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Uecker, Karl; Retzmann, Dietmar [Siemens AG, Erlangen (Germany). HVDC/Facts Sales and Marketing; Schultze, Alberto [Siemens AG, Erlangen (Germany). Abt. Grid Access and Industry

    2010-09-06

    Due to the global climate change, the power industry has a lot of changes in store. For reasons of environmental protection, the reduction in CO{sub 2} emissions in power generation and loss minimization in power transmission are of particular importance. This means that the share of wind power in a lot of countries, Germany among them, must be as high as possible, for the other &apos;'green'&apos; energy resources, such as hydro or solar power, play only a subordinate part for reasons of their geographical location. Along with sustainability and efficiency of power supply, grid security must be taken into account as well. (orig.)

  16. The &apos;'Stadtkante'&apos; building at Dusseldorf. Representative address of the Metro Group; Die Stadtkante in Duesseldorf. Repraesentative Adresse der Metro Group

    Energy Technology Data Exchange (ETDEWEB)

    Zerres, E.

    2006-07-01

    The &apos;Stadtkante&apos; building of the Metro Group was commissioned in June 2005. The building houses offices and a shopping mall. It has an aesthetically pleasing architecture and interesting technical features. (orig.)

  17. Residues in the 5th module of the low-density lipoprotein receptor that bind apoE and apoB-100

    International Nuclear Information System (INIS)

    Kroon, P.A.; Zhang, H.-Y.; Smith, R.

    2000-01-01

    Full text: The low-density lipoprotein receptor (LDLR) binds and removes cholesterol-rich lipoproteins from the circulation. Its ligand-binding (LB) domain consists of seven cysteine-rich LB modules that bind apoB-100 and apoE. These modules fold into well-defined structures with three disulfide bonds, in the presence of Ca 2+ . The 5th module (LB5) is unique in that it is required to bind both apoB-100 and apoE. The aim of the current study was to map residues in human LB5 that are required for ligand binding. This was done by alanine mutagenesis of a series of residues that are conserved in human, mouse, rat and rabbit LB5 (E9, S14, E16, H19, S21, K31, and K33), but not in the other six modules. E37 (R37 in the rabbit) was included, since it has been previously hypothesized to play a role in binding. The variant LB5 modules were first produced as recombinant peptides, and subjected to oxidative folding to determine whether the mutations interfered with Ca 2+ '-dependent folding. Only the S14A and E16A mutations interfered significantly with folding, suggesting that S14 and E16 are required for the structural framework of LB5 and that their substitution in the LDLR may interfere with its folding. The native LDLR and E9A, H19A, S21A, K31A, K33A and E37A LDLRs were expressed in LDLR negative IdlA-7 CHO cells. Labeling with 125 I-lgG-C7 showed that all receptors were expressed on the cell surface. Binding of Dil-labeled LDL (Dil-LDL) and Dil-labeled DMPC, complexed with the N-terminal receptor-binding domain of apoE3 (Dil-E3), at 4 deg C, was used to assess receptor binding. Binding of Dil-E3 (0.1 μ/ml) to the H19A, S21A, K31A, K33A and E37A LDLRs was 65-92% of binding to the native LDLR. In contrast, the E9A LDLR only bound 3% of that of the native LDLR. The binding of Dil-LDL (0.5 Ag/ml) to the E9A LDLR was 23% of that of the native LDLR, while binding to the remaining variant LDLRs ranged from 44-70% of what of the native LDLR. We conclude that (i) E9 of LB5

  18. Wetlands construídos empregados no tratamento descentralizado de águas cinzas residencial e de escritório

    OpenAIRE

    Monteiro, Victória Regina Celso

    2014-01-01

    Dissertação (mestrado) - Universidade Federal de Santa Catarina, Centro Tecnológico, Programa de Pós-Graduação em Engenharia Ambiental, Florianópolis, 2014. Dentre as tecnologias de saneamento descentralizado mais utilizadas para o tratamento de águas cinzas (AC), destacam-se os wetlands construídos. Este trabalho tem como objetivo geral avaliar o comportamento de wetlands construídos de fluxo horizontal (WH) e vertical (WV) empregados no tratamento de AC residencial e de escritório, respe...

  19. Custo econômico do tratamento das úlceras por pressão: uma abordagem teórica

    Directory of Open Access Journals (Sweden)

    Ana Julia Silva

    2013-08-01

    Full Text Available O presente artigo consiste numa abordagem teórica sobre a problemática dos custos económicos das úlceras por pressão. Parte-se do conhecimento do problema, numa perspetiva conceptual, para, de seguida, apresentar resultados de estudos de prevalência, a partir dos quais foram delineados estudos de impacto económico. O objectivo deste artigo é o de reflectir sobre os custos económicos associados às úlceras por pressão, quer numa perspetiva global, considerando a repercussão financeira, quer numa vertente personalista, atendendo aos custos intangíveis. Relativamente ao impacto económico das úlceras por pressão, foi efectuada uma estimativa ao nível da Região Autónoma dos Açores do custo total do tratamento por ambiente de cuidados. Nos cuidados domiciliários o custo com o tratamento de todas as categorias é calculado em 7.086.415 euros; nos cuidados hospitalares, em 1.723.509 euros, e nos cuidados prestados em lares de idosos, em 1.002.562 euros. Nos Açores, a estimativa do custo total do tratamento das úlceras por pressão, considerando todas as suas categorias, ronda os 9.812.486 euros. Quanto ao impacto emocional associado, este tem elevados custos para pessoa e para os familiares, nomeadamente pelo sofrimento gerado. De facto, as úlceras por pressão acarretam elevados custos económicos associados ao tratamento, bem como custos intangíveis pelo sofrimento vivenciado por pessoas e cuidadores.

  20. Characterization and evaluation of residue &apos;grits&apos; of the cellulose industry; Caracterizacao e avaliacao do resisduo &apos;grits&apos; da industria de celulose

    Energy Technology Data Exchange (ETDEWEB)

    Destefani, A.Z.; Santos, M.M.; Holanda, J.N.F. [Universidade Estadual do Norte Fluminense Darcy Ribeiro (LAMAV/CCT/UENF), Campos dos Goytacazes, RJ (Brazil). Lab. de Materiais Avancados

    2010-07-01

    The cellulose industry generates huge amounts of solid waste residue called &apos;grits&apos;. These wastes have been willing over time in landfills near the mills. However, this type of disposal is not environmentally friendly and can cause degradation and environmental pollution. In addition, environmental legislation increasingly severe and the high costs of landfill have led the search for new alternatives for final disposition of this abundant waste. In this context, this study is to characterize waste grits, generated by the cellulose industry in the region of Aracruz-ES. The residue samples were characterized in terms of chemical composition, X-ray diffraction, particle size distribution and thermal analysis (DTA and TGA). The characterization of the residual &apos;grits&apos; demonstrated its potential as a feedstock for production of soil-cement bricks. (author)

  1. GAINING CONSENSUS: THE STORY OF &apos;&apos;OAK RIDGE TENNESSEE - A CITIZEN&apos;S GUIDE TO THE ENVIRONMENT&apos;&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Craig, Robert; Freeman, Jenny; Gawarecki, Susan L; Hardy, Parker; Kopp, Steve; Mulvenon, Norman A; Pardue, William; Sarno, Doug

    2003-02-27

    In 2001, a diverse group of citizens ranging from conservationists to industrial developers joined forces to produce a factual description of Oak Ridge&apos;s environment and the issues associated with contamination on the U.S. Department of Energy (DOE) reservation. This consensus effort was a result of common values not generally seen in this spectrum of philosophies, and of shared concerns about rising property taxes, declining city services, fleeing retail establishments, and diminishing real estate values. These problems are attributed to waning local DOE budgets coupled with Oak Ridge&apos;s national reputation of being contaminated and unsafe. This undeserved reputation harms the city&apos;s ability to attract new industry to replace declining federal employment and to induce families to live in the community. Representatives from a spectrum of conservation, environmental, economic development, local government, and civic organizations were invited to meet regarding how to best explain the complex environmental story of Oak Ridge and the DOE reservation. This large group decided to publish a straightforward explanation of the environmental quality of the city and its relationship to the DOE reservation in easy-to-understand language. The result was Oak Ridge, Tennessee--A Citizen&apos;s Guide to the Environment, a 28-page glossy booklet, distributed through the Chamber of Commerce and other organizations. The Oak Ridger ensured wide distribution in the community by publishing it as an insert in the daily paper. The material is also available on several web sites. A trifold brochure summarizing and promoting the larger document was also produced for wider distribution. The integrity of the Citizen&apos;s Guide was ensured by having a six-member editorial team manage writing and review of the document. There was no direct involvement by the DOE and its contractor. Knowledgeable citizen writers from throughout the community contributed technical and descriptive

  2. Sustainable Agriculture: enhancement of the &apos;neem cake&apos;

    International Nuclear Information System (INIS)

    Susanna, Mariani

    2015-01-01

    The &apos;neem cake&apos; scrap processing of the industrial chain producing neem oil and azadirachtin. The ENEA laboratories have developed a promising trial to promote the use of neem cake as a low-cost insecticide and fertilizer in sustainable agriculture. [it

  3. Clonixinato de lisina injetável intravenoso para o tratamento agudo das enxaquecas: um estudo piloto aberto

    OpenAIRE

    KRYMCHANTOWSKI, ABOUCH V.; BARBOSA, JACKELINE

    1999-01-01

    Alguns antinflamatórios não esteroidais (AINE) orais são eficientes para o tratamento dos ataques de migrânea ou enxaqueca. A despeito de sua eficiência para o tratamento destas cefaléias e de outras dores, existem comercialmente poucos antinflamatórios não esteroidais disponíveis para administração parenteral. O clonixinato de lisina (CL) é um AINE derivado do ácido nicotínico que foi comprovadamente eficiente em vários tipos de síndromes álgicas como cólica renal, dor de compressão nervosa,...

  4. Tratamento conservador de fluorose dentária: a propósito de um caso clínico

    OpenAIRE

    Pereira, Fátima Patrícia Couto Oliveira

    2017-01-01

    A fluorose dentária é uma anomalia do esmalte dentário que surge como consequência de um aporte excessivo de flúor aquando da formação dentária. Quando ingerido acima do limite máximo, sendo a dosagem recomendada 0,05 a 0,07 mg F/Kg peso corporal/dia, afeta a mineralização do esmalte dentário contribuindo para uma estética deficiente. Objetivos: Esta revisão narrativa tem como objetivo dar a conhecer um dos tratamentos conservadores inovadores no tratamento de manchas brancas dentárias des...

  5. Atrofia muscular espinhal: diagnóstico, tratamento e perspectivas futuras

    Directory of Open Access Journals (Sweden)

    Mariana T. C. Baioni

    2010-08-01

    Full Text Available OBJETIVO: Relatar as recentes descobertas genéticas e moleculares, juntamente com as perspectivas futuras, para o tratamento da atrofia muscular espinhal, auxiliando, dessa forma, os profissionais da área da saúde a fazerem um rápido diagnóstico e proporcionarem um suporte terapêutico correto e precoce. FONTES DOS DADOS: As informações foram coletadas a partir de artigos científicos publicados nas duas últimas décadas, pesquisados nas bases de dados SciELO, PubMed e MEDLINE. SÍNTESE DOS DADOS: A atrofia muscular espinhal é uma doença neurodegenerativa com herança genética autossômica recessiva. É causada por uma deleção homozigótica do gene de sobrevivência do motoneurônio. Essa alteração genética resulta na redução dos níveis da proteína de sobrevivência do motoneurônio, levando à degeneração de motoneurônios alfa da medula espinhal, o que resulta em fraqueza e paralisia muscular proximal progressiva simétrica. Sabe-se que alguns cuidados básicos referentes à nutrição, respiração e fisioterapia podem ser importantes para retardar o progresso da doença e prolongar a vida dos pacientes. Vários medicamentos estão sendo testados, alguns novos, outros já conhecidos, como o ácido valproico, sendo que a paralisia pode ser estacionada, mas não revertida. CONCLUSÕES: A atrofia muscular espinhal é uma desordem de difícil diagnóstico, por ser pouco conhecida, e de tratamento ainda incerto. Os tratamentos farmacológicos e as terapias de suporte existentes ainda não são capazes de recuperar os motoneurônios ou as células musculares que já foram perdidos, mas têm o objetivo de retardar o progresso da doença e melhorar a função muscular residual dos pacientes, bem como oferecer uma melhor qualidade e expectativa de vida.

  6. Lung inflammation and genotoxicity following pulmonary exposure to nanoparticles in ApoE-/- mice

    Directory of Open Access Journals (Sweden)

    Ladefoged Ole

    2009-01-01

    Full Text Available Abstract Background The toxic and inflammatory potential of 5 different types of nanoparticles were studied in a sensitive model for pulmonary effects in apolipoprotein E knockout mice (ApoE-/-. We studied the effects instillation or inhalation Printex 90 of carbon black (CB and compared CB instillation in ApoE-/- and C57 mice. Three and 24 h after pulmonary exposure, inflammation was assessed by mRNA levels of cytokines in lung tissue, cell composition, genotoxicity, protein and lactate dehydrogenase activity in broncho-alveolar lavage (BAL fluid. Results Firstly, we found that intratracheal instillation of CB caused far more pulmonary toxicity in ApoE-/- mice than in C57 mice. Secondly, we showed that instillation of CB was more toxic than inhalation of a presumed similar dose with respect to inflammation in the lungs of ApoE-/- mice. Thirdly, we compared effects of instillation in ApoE-/- mice of three carbonaceous particles; CB, fullerenes C60 (C60 and single walled carbon nanotubes (SWCNT as well as gold particles and quantum dots (QDs. Characterization of the instillation media revealed that all particles were delivered as agglomerates and aggregates. Significant increases in Il-6, Mip-2 and Mcp-1 mRNA were detected in lung tissue, 3 h and 24 h following instillation of SWCNT, CB and QDs. DNA damage in BAL cells, the fraction of neutrophils in BAL cells and protein in BAL fluid increased statistically significantly. Gold and C60 particles caused much weaker inflammatory responses. Conclusion Our data suggest that ApoE-/- model is sensitive for evaluating particle induced inflammation. Overall QDs had greatest effects followed by CB and SWCNT with C60 and gold being least inflammatory and DNA-damaging. However the gold was used at a much lower mass dose than the other particles. The strong effects of QDs were likely due to Cd release. The surface area of the instilled dose correlated well the inflammatory response for low toxicity particles.

  7. Luxação acromioclavicular: tratamento e reabilitação. Perspectivas e tendências atuais do ortopedista brasileiro

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    Gustavo Gonçalves Arliani

    2015-10-01

    Full Text Available Resumo Objetivo: Avaliar as condutas e os procedimentos feitos pelos cirurgiões ortopédicos do Brasil no tratamento e na reabilitação das luxacões acromioclaviculares do ombro. Métodos: Foi aplicado um questionário de oito questões fechadas que abordavam tópicos relacionados ao tratamento e à reabilitação das luxacões acromioclaviculares aos cirurgiões ortopédicos brasileiros nos três dias do 45° Congresso Brasileiro de Ortopedia e Traumato logia de 2013. ResuItados: Preencheram completamente o questionário e fizeram parte da amostra ana lisada 122 cirurgiões. A maior parte era proveniente da Região Sudeste. Na amostra, 67% dos participantes optariam pelo tratamento cirúrgico em pacientes com luxação acro mioclavicular grau 3. Em relacão à técnica preferida para tratamento cirúrgico das luxacões acromioclaviculares agudas, a maioria dos cirurgiões usa amarrilho subcoracoide com fixacão acromioclavicular e transferência do ligamento coracoacromial (25,4%. Quando perguntados sobre complicates encontradas após a cirurgia, 43,4% e 32,8% dos partici pantes, respectivamente, responderam que deformidade residual na articulação operada e dor foram as complicates mais vistas no período pós-operatório. Conclusoes: Apesar de não haver consenso no tratamento e na reabilitação das luxacões acro mioclaviculares, há evolucão em alguns tópicos analisados no questionário aplicado para os ortopedistas nacionais. No entanto, mais estudos prospectivos controlados são necessários para avaliar o benefício clínico e científico dessas tendências.

  8. Marysville, Montana, Geothermal Project: Geological and Geophysical Exploration at Marysville Geothermal Area: 1973 Results (With a Section on &apos;&apos;Contemporary Seismicity in the Helena, Montana Region&apos;&apos;)

    Energy Technology Data Exchange (ETDEWEB)

    Blackwell, D.D.; Brott, C.A.; Goforth, T.T.; Holdaway, M.J.; Morgan, P.; Friedline, R.; Smith, R.L.

    1974-04-01

    This report describes field geological and geophysical investigations of the Marysville geothermal area, including geological mapping, sample collection, a ground total field magnetic survey, gravity survey, seismic ground noise survey, microearthquake survey, and heat flow study. Although sufficient data are not available, it is likely that a magma chamber is the heat source. A second section, &apos;&apos;Contemporary Seismicity in the Helena, Montana, Region&apos;&apos; examines the coincidence of high heat flow and earthquake swarm activity in this region. (GRA)

  9. Tratamento farmacológico dos transtornos alimentares Pharmacological treatment of eating disorders

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    Jose C Appolinario

    2002-12-01

    Full Text Available O tratamento dos transtornos alimentares (TA geralmente exige uma abordagem multidisciplinar em que a farmacoterapia é adjuvante de abordagens psicológicas e nutricionais. Psicotrópicos são indicados para a maioria dos pacientes com TA para tratar as comorbidades e também os sintomas chamados nucleares. Progressos importantes estão ocorrendo nos últimos anos. Este artigo apresenta uma revisão das evidências atuais e perspectivas futuras para o tratamento farmacológico da anorexia nervosa, bulimia nervosa e do transtorno da compulsão alimentar periódica.The treatment of eating disorders (ED usually involves a multidisciplinary approach and pharmacotherapy is adjunctive to psychological and nutritional interventions. Psychotropic agents are prescribed for most patients with ED to treat both the comorbid conditions and ED core symptoms. Important progresses have occurred in the last years. We present an overview of the current evidences and future directions in the pharmacological treatment of anorexia nervosa, bulimia nervosa and binge eating disorder.

  10. Atualização no tratamento profilático das enxaquecas

    Directory of Open Access Journals (Sweden)

    KRYMCHANTOWSKI ABOUCH VALENTY

    1999-01-01

    Full Text Available Dentre as cefaléias primárias, pacientes com migrânea ou enxaqueca são os que mais procuram assistência médica. A sua prevalência é estimada em 12% da população sendo mais comum em mulheres com média de 18 a 20%, de 6% nos homens e de 4 a 8% nas crianças. O impacto econômico na produtividade e lazer é significativo, e as crises incapacitam o paciente para as atividades habituais. Com fisiopatologia complexa e ainda insuficientemente conhecida, a migrânea pode cursar com ataques de cefaléia intermitente, intensa e com características peculiares. A abordagem mais eficiente para o tratamento inclui o afastamento dos fatores deflagradores, tratamento medicamentoso preventivo, uso de medicamentos de resgate para os momentos de dor, e as terapias acessórias ou não medicamentosas. Para o tratamento profilático, objeto desta avaliação, utilizam-se várias classes de medicamentos que incluem os beta bloqueadores, antidepressivos tricíclicos (e mais recentemente inibidores seletivos da recaptação da serotonina, antagonistas dos canais de cálcio, antagonistas da serotonina, anticonvulsivantes e outros. Embora os seus mecanismos de ação nas migrâneas ainda sejam desconhecidos, parece que todos atuam nas funções serotoninérgica, noradrenérgica e gabaérgica centrais. Novas propostas de mecanismos de ação para algumas destas drogas incluem a inibição da formação do óxido nítrico e a ação específica de modulação em canais catiônicos neuronais. Quando individualizados e usados corretamente, estes medicamentos preventivos têm sido responsáveis por reduções importantes na frequência e intensidade dos episódios de migrânea, diminuindo assim o sofrimento e condutas duvidosas às quais os pacientes são usualmente submetidos.

  11. Adesão ao tratamento no transtorno bipolar

    OpenAIRE

    Santin,Aida; Ceresér,Keila; Rosa,Adriane

    2005-01-01

    O transtorno bipolar (TB) é uma doença crônica, recorrente, presente em 1,5% da população, estando associada a altas taxas de mortalidade e prejuízos socioeconômicos. O lítio, a carbamazepina e o ácido valpróico são os estabilizadores de humor mais usados. Em tratamentos prolongados, como é o caso do TB, a má-adesão dos pacientes é uma das maiores dificuldades. Verifica-se que fatores ligados ao paciente, aos medicamentos e aos médicos possam ser responsáveis pela baixa adesão. A psicoeducaçã...

  12. An Analysis of Department of Defense Instruction 8500.2 &apos;Information Assurance (IA) Implementation.&apos;

    Energy Technology Data Exchange (ETDEWEB)

    Campbell, Philip LaRoche

    2012-01-01

    The Department of Defense (DoD) provides its standard for information assurance in its Instruction 8500.2, dated February 6, 2003. This Instruction lists 157 &apos;IA Controls&apos; for nine &apos;baseline IA levels.&apos; Aside from distinguishing IA Controls that call for elevated levels of &apos;robustness&apos; and grouping the IA Controls into eight &apos;subject areas&apos; 8500.2 does not examine the nature of this set of controls, determining, for example, which controls do not vary in robustness, how this set of controls compares with other such sets, or even which controls are required for all nine baseline IA levels. This report analyzes (1) the IA Controls, (2) the subject areas, and (3) the Baseline IA levels. For example, this report notes that there are only 109 core IA Controls (which this report refers to as &apos;ICGs&apos;), that 43 of these core IA Controls apply without variation to all nine baseline IA levels and that an additional 31 apply with variations. This report maps the IA Controls of 8500.2 to the controls in NIST 800-53 and ITGI&apos;s CoBIT. The result of this analysis and mapping, as shown in this report, serves as a companion to 8500.2. (An electronic spreadsheet accompanies this report.)

  13. Avaliação da condição gengival e microbiológica subgengival de pacientes sadios periodontalmente submetidos a tratamento ortodôntico

    OpenAIRE

    Menezes Cardoso, Randerson

    2011-01-01

    Objetivo: Avaliar a condição gengival e a presença na microbiota subgengival das bactérias Aggregatibacter actinomycetemcomitans (Aa) e Tannerella forsythia (Tf) em pacientes periodontalmente saudáveis submetidos a tratamento ortodôntico com aparelho fixo. Material e Métodos: Vinte pacientes foram distribuídos em dois grupos (n=10) de acordo com a necessidade de tratamento ortodôntico (Grupo Teste = apresentavam má oclusão e receberam tratamento ortodôntico; Grupo Controle =...

  14. Euratom framework programme research in reactor safety main achievements of FP-4 (&apos;94-&apos;98), some preliminary results of FP-5 (&apos;98-&apos;02) and prospects for beyond 2002

    Energy Technology Data Exchange (ETDEWEB)

    Goethem, G. van; Martin Bermejo, J.; Zurita, A.; Lemaitre, P. [Commission of the European Communities, Brussels (BE). Directorate General for Science, Research and Development (DG 12)

    2001-07-01

    In this paper an overview is given of the most important aspects of the research activities organised by the European union (EU) in reactor safety, more specifically in the area &apos;&apos;Operational Safety of Existing Installations&apos;&apos;, which is one of the 4 areas of the key action Nuclear Fission in the 5th Euratom framework programme (FP-5). In the introduction, a short description is given of the EU needs and the new boundary conditions for Euratom research. In the next 7 sections, the attention is drawn to a series of technical and socio-economical facts, which generate needs at the EU level and hence justify some actions - especially in terms of research - at the Commission level. The following needs have been identified and are proposed for discussion: to maintain the nuclear option open in order to ensure flexibility in energy supply; to maintain scientific and technical competence; to maintain industrial competitiveness and to prepare the next generation of reactors; to maintain a broad nuclear expertise covering both energetic and non-energetic applications; to develop environment-friendly sustainable solutions for the wastes; to share and improve the safety culture amongst the EU countries and the CEECs; and finally, to focus on public benefit and on added European value in Euratom research actions. A brief overview then is given of the European response - in terms of research - offered up to 2002 to contribute to meet some of the above needs, i.e. the Euratom research actions under FP-4 (&apos;94-&apos;98) and FP-5 (&apos;98-&apos;02). As far as the future beyond 2002 is concerned, the challenge to Euratom research is to identify networks of excellence and to reorganize itself in line with the new ERA concept (European research area). Finally conclusions are drawn on the perceived need to improve the fitness-for-purpose of Euratom research actions in the &apos;&apos;changing world&apos;&apos; and to rethink accordingly the organisation of

  15. Evaluatie van de smogsituatie in de winterperioden &apos;92/&apos;93, &apos;93/&apos;94 en &apos;94/&apos;95

    NARCIS (Netherlands)

    Anker IM van de; LLO

    1996-01-01

    In Nederland bestaat sinds 20 juni 1991 een nieuwe smogregeling, het zogenaamde Modeldraaiboek Smog 1991. In dit modeldraaiboek zijn procedures, maatregelen, handelingen, signaleringsschema&apos;s en aanbevelingen vastgelegd welke betrekking hebben op perioden met verhoogde luchtverontreiniging

  16. Comparação de ibuprofeno via oral e indometacina intravenosa no tratamento da persistência do canal arterial em neonatos com extremo baixo peso ao nascer

    Directory of Open Access Journals (Sweden)

    Eun Mi Yang

    2013-02-01

    Full Text Available OBJETIVO: Existem poucos relatórios publicados com relação à eficácia do ibuprofeno via oral no tratamento da persistência do canal arterial (PCA em neonatos com extremo baixo peso ao nascer (EBPN. Comparamos o ibuprofeno via oral à indometacina intravenosa no que diz respeito à eficácia e segurança no tratamento de PCA em neonatos com peso inferior a 1.000 g ao nascer. MÉTODO: Este foi um estudo retrospectivo em um único centro. Coletamos dados de neonatos com EBPN que tiveram PCA ecocardiograficamente confirmada. Os neonatos foram tratados tanto com indometacina intravenosa quanto com ibuprofeno via oral. A taxa de fechamento do canal, a necessidade de tratamentos adicionais, os efeitos colaterais ou as complicações relacionadas ao medicamento e a mortalidade foram comparados entre os dois grupos de tratamento. RESULTADO: Examinamos 26 neonatos que receberam indometacina e 22 que receberam ibuprofeno. A taxa geral de fechamento do canal foi semelhante nos dois tratamentos: o fechamento do canal ocorreu em 23 dos 26 neonatos (88,5% no grupo indometacina, e em 18 dos 22 neonatos (81,8% no grupo ibuprofeno (p = 0,40. A taxa de ligadura cirúrgica (11,5% em comparação a 18,2%; p = 0,40 não diferiu de forma significativa entre os dois grupos de tratamento. Após o tratamento, não foi encontrada nenhuma diferença significativa nas concentrações de creatinina sérica entre os dois grupos. Não houve diferenças significativas com relação a efeitos colaterais ou complicações adicionais. CONCLUSÃO: Em neonatos com EBPN, o ibuprofeno via oral é tão eficaz quanto a indometacina intravenosa no tratamento da PCA. Não há diferenças entre os medicamentos no que diz respeito à segurança. O ibuprofeno via oral poderia ser usado como um agente alternativo no tratamento da PCA em neonatos com EBPN.

  17. MR evaluation of &apos;Metaphyseal&apos; change in Legg-Calve-Perthes disease

    Energy Technology Data Exchange (ETDEWEB)</