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Sample records for anxiety health-related quality

  1. Health-related Quality of Life across the Anxiety Disorders: Findings from a Sample of Primary Care Patients

    OpenAIRE

    Beard, Courtney; Weisberg, Risa B.; Keller, Martin B.

    2010-01-01

    Previous studies have not compared Health-related Quality of Life (HR-QoL) across all DSM-IV anxiety disorders and comorbid conditions. We compared the effects of each anxiety disorder on HR-QoL, controlling for demographic variables, medical conditions, and comorbid Axis I disorders. Data are obtained from the Primary Care Anxiety Project (PCAP), a naturalistic, longitudinal study of anxiety disorders in 539 primary care patients. Each of the anxiety disorders was associated with worse self-...

  2. Disability and health-related quality of life in outpatients with generalised anxiety disorder treated in psychiatric clinics: is there still room for improvement?

    OpenAIRE

    Vilardaga Inma; Caballero Luis; Bobes Julio; Rejas Javier

    2011-01-01

    Abstract Objective We assessed the impact of generalised anxiety disorder (GAD) on disability and health-related quality of life in outpatients treated in psychiatric clinics via a secondary analysis conducted in 799 patients from a cross-sectional study of prevalence of GAD in psychiatric clinics. Methods Patients were allocated into two groups: follow-up (15.7%) and newly diagnosed patients (84.3%), and were administered the Hamilton Anxiety Scale (HAM-A), Clinical Global Impressions Scale ...

  3. The impact of Type D personality on health-related quality of life in tinnitus patients is mainly mediated by anxiety and depression

    DEFF Research Database (Denmark)

    Bartels, Hilke; Pedersen, Susanne S.; van der Laan, Bernard F A M;

    2010-01-01

    To evaluate the impact of Type D personality on health-related quality of life (HRQoL) and self-reported tinnitus-related distress in chronic tinnitus patients and whether this relationship is mediated by indicators of psychological distress (i.e., vital exhaustion, anxiety, and depression)....

  4. Depression, anxiety, stress, social interaction and health-related quality of life in men and women with unexplained chest pain

    Directory of Open Access Journals (Sweden)

    Manhem Karin

    2008-05-01

    Full Text Available Abstract Background Unexplained chest pain (UCP is a common reason for emergency hospital admission and generates considerable health-care costs for society. Even though prior research indicates that psychological problems and impaired quality of life are common among UCP patients, there is lack of knowledge comparing UCP patients with a reference group from the general population. The aim of this study was to analyse differences between men and women with UCP and a reference group in terms of psychosocial factors as depression, anxiety, stress, social interaction and health-related quality of life (HRQOL. Methods A self-administered questionnaire about psychosocial factors was completed by 127 men and 104 women with acute UCP admitted consecutively to the Emergency Department (ED or as in-patients on a medical ward. A reference group from the general population, 490 men and 579 women, participants in the INTERGENE study and free of clinical heart disease, were selected. Results The UCP patients were more likely to be immigrants, have a sedentary lifestyle, report stress at work and have symptoms of depression and trait-anxiety compared with the reference group. After adjustment for differences in age, smoking, hypertension and diabetes, these factors were still significantly more common among patients with UCP. In a stepwise multivariate model with mutual adjustment for psychosocial factors, being an immigrant was associated with a more than twofold risk in both sexes. Stress at work was associated with an almost fourfold increase in risk among men, whereas there was no independent impact for women. In contrast, depression only emerged as an independent risk factor in women. Trait-anxiety and a low level of social interaction were not independently associated with risk in either men or women. Patients with UCP were two to five times more likely to have low scores for HRQOL. Conclusion Both men and women with UCP had higher depression scores

  5. Association of oral health related quality of life with dental anxiety and depression along with general health among people of Bhopal district, Madhya Pradesh

    OpenAIRE

    Shet, RGK; Jain, Gaurvi; Maroli, Sohani; Srivastava, Kirti Jajoo; Kasina, Sitaram Prasad; Shwetha, GS

    2013-01-01

    Background: To associate oral health related quality of life with dental anxiety and depression along with general health among people of Bhopal district, Madhya Pradesh. Materials & Methods: A cross sectional questionnaires based survey was conducted among the subjects of Bhopal district, Madhya Pradesh. The survey was carried among 101 subjects aging from 20-40 years. Subjects under investigation were belonging to various occupations. They were assigned a questionnaire. Questionnai...

  6. Health-related quality of life, anxiety and depression in the diagnostic phase of suspected cancer, and the influence of diagnosis

    DEFF Research Database (Denmark)

    Larsen, Ellen Frøsig Moseholm; Rydahl Hansen, Susan; Overgaard, Dorthe;

    2016-01-01

    Background Undergoing diagnostic evaluation for cancer has been associated with a high prevalence of anxiety and depression and affected health-related quality of life (HRQoL). The aims of this study were to assess HRQoL, anxiety, and depression pre- and post-diagnosis in patients undergoing...... patients with non-cancer diagnoses were calculated. The impact of baseline psychological, socio-demographic, and medical factors on HRQoL, anxiety and depression at follow-up was explored by bootstrapped multivariate linear regression analyses and logistic regression analyses. Results A total of 838...... were no intra- or inter-group differences in the depression scores. The strongest predictors of global QL, anxiety, and depression after a known diagnosis were baseline scores, co-morbidity and poor self-rated health. Conclusions Patients undergoing diagnostic evaluations for cancer based on non...

  7. Depression, anxiety and their comorbidity in the Swedish general population: point prevalence and the effect on health-related quality of life

    Directory of Open Access Journals (Sweden)

    Robert Johansson

    2013-07-01

    Full Text Available Background. Depression and anxiety disorders are major world-wide problems. There are no or few epidemiological studies investigating the prevalence of depression, generalized anxiety disorder and anxiety disorders in general in the Swedish population. Methods. Data were obtained by means of a postal survey administered to 3001 randomly selected adults. After two reminders response rate was 44.3%. Measures of depression and general anxiety were the 9-item Patient Health Questionnaire Depression Scale (PHQ-9 and the 7-item Generalized Anxiety Disorder Scale (GAD-7. The PHQ-9 identified participants who had experienced clinically significant depression (PHQ-9 ≥ 10, and who had a diagnosis of major depression (defined by using a PHQ-9 scoring algorithm. Clinically significant anxiety was defined as having a GAD-7 score ≥ 8. To specifically measure generalized anxiety disorder, the Generalized Anxiety Disorder Questionnaire-IV (GAD-Q-IV was used with an established cut-off. Health-related quality of life was measured using the EuroQol (EQ-5D. Experiences of treatments for psychiatric disorders were also assessed. Results. Around 17.2% (95% CI: 15.1–19.4 of the participants were experiencing clinically significant depression (10.8%; 95% CI: 9.1–12.5 and clinically significant anxiety (14.7%; 95% CI: 12.7–16.6. Among participants with either clinically significant depression or anxiety, nearly 50% had comorbid disorders. The point prevalence of major depression was 5.2% (95% CI: 4.0–6.5, and 8.8% (95% CI: 7.3–10.4 had GAD. Among those with either of these disorders, 28.2% had comorbid depression and GAD. There were, generally, significant gender differences, with more women having a disorder compared to men. Among those with depression or anxiety, only between half and two thirds had any treatment experience. Comorbidity was associated with higher symptom severity and lower health-related quality of life. Conclusions. Epidemiological

  8. Application of Dyadic Data Analysis in Pediatric Psychology: Cystic Fibrosis Health-Related Quality of Life and Anxiety in Child–Caregiver Dyads

    OpenAIRE

    Driscoll, Kimberly A.; Schatschneider, Christopher; McGinnity, Kelly; Modi, Avani C.

    2012-01-01

    Objective To demonstrate the use of the actor–partner interdependence model (APIM) of dyadic relationships in a sample of children with cystic fibrosis (CF) and their caregivers. Methods Multilevel modeling evaluated relations between health-related quality of life (HRQOL) and anxiety in 29 child–caregiver dyads. The following effects were evaluated: actor and partner, and the respondent (i.e., child or caregiver) × HRQOL interaction. Results This study demonstrated a practical application of...

  9. Oral health-related quality of life and depression/anxiety in long-term recurrence-free patients after treatment for advanced oral squamous cell cancer.

    Science.gov (United States)

    Hassel, Alexander J; Danner, Daniel; Freier, Kolja; Hofele, Christof; Becker-Bikowski, Kirsten; Engel, Michael

    2012-06-01

    This report focuses on the association between oral health-related quality of life (OHRQoL) and depression/anxiety of a homogeneous group of cancer patients who were recurrence-free for 8 years after treatment for advanced oral squamous cell. Participants were 24 patients (mean age 55 years, 75% men) treated with neoadjuvant concurrent radiochemotherapy followed by surgery with a mean recurrence-free period of 95 months (from 39 to 164 months). The OHRQoL (OHIP) and the anxiety/depression (HADS) were assessed twice (1 year between t1 and t2). OHRQoL was impaired in this group (mean OHIP score 65 units). In cross-lagged correlation analysis, the correlation between OHRQoL to t1 and depression to t2 was significant and greater than the non-significant correlation for depression to t1 and OHRQoL to t2 indicating that OHRQoL predicts depression better than vice versa. However, the difference in the correlation coefficients was not significant (ZPF-test). The same was true for OHRQoL and anxiety. The OHRQoL measured with the OHIP was impaired in comparison to the normal population. In the limitations of the study design and bearing the small sample size in mind, the results give evidence that OHRQoL predicts psychological outcomes, namely depression and anxiety, better than vice versa. PMID:21733701

  10. Depression and anxiety predict health-related quality of life in chronic obstructive pulmonary disease: systematic review and meta-analysis

    Directory of Open Access Journals (Sweden)

    Blakemore A

    2014-05-01

    Full Text Available Amy Blakemore,1,2 Chris Dickens,3 Else Guthrie,2 Peter Bower,1 Evangelos Kontopantelis,1 Cara Afzal,2 Peter A Coventry4 1National Institute for Health Research School for Primary Care Research, Centre for Primary Care, Manchester Academic Health Science Centre, University of Manchester, 2Department of Psychiatry, Manchester Mental Health and Social Care Trust, Manchester Royal Infirmary, Manchester, UK; 3Institute of Health Service Research, University of Exeter Medical School and Peninsula Collaboration for Leadership in Health Research and Care, University of Exeter, Exeter, UK; 4Collaboration for Leadership in Applied Health Research and Care for Greater Manchester and Manchester Academic Health Science Centre, University of Manchester, Manchester, UK Background: The causal association between depression, anxiety, and health-related quality of life (HRQoL in chronic obstructive pulmonary disease (COPD is unclear. We therefore conducted a systematic review of prospective cohort studies that measured depression, anxiety, and HRQoL in COPD. Methods: Electronic databases (Medline, Embase, Cumulative Index to Nursing and Allied Health Literature [CINAHL], British Nursing Index and Archive, PsycINFO and Cochrane database were searched from inception to June 18, 2013. Studies were eligible for inclusion if they: used a nonexperimental prospective cohort design; included patients with a diagnosis of COPD confirmed by spirometry; and used validated measures of depression, anxiety, and HRQoL. Data were extracted and pooled using random effects models. Results: Six studies were included in the systematic review; of these, three were included in the meta-analysis for depression and two were included for the meta-analysis for anxiety. Depression was significantly correlated with HRQoL at 1-year follow-up (pooled r=0.48, 95% confidence interval 0.37–0.57, P<0.001. Anxiety was also significantly correlated with HRQoL at 1-year follow-up (pooled r=0.36, 95

  11. Subsyndromal Depression and Anxiety in Older Adults: Health Related, Functional, Cognitive and Diagnostic Implications

    OpenAIRE

    Kasckow, JW; Karp, JF; Whyte, E; Butters, M; Brown, C.; Begley, A.; Bensasi, S; Reynolds, CF

    2013-01-01

    Subsyndromal depression in later life is common in primary care. Comorbid anxiety disorders could exacerbate the negative effect of subsyndromal depression on functioning, health-related quality of life, comorbidity and/or cognition. We examined anxiety disorders coexisting with subsyndromal depression in participants ≥ age 50 in an NIH trial of Problem Solving Therapy for Primary Care for indicated prevention of major depression. There were 247 participants, with Centers for Epidemiologic St...

  12. Health-Related Quality of Life

    DEFF Research Database (Denmark)

    Linde, Louise; Sørensen, Jan; Ostergaard, Mikkel;

    2008-01-01

    OBJECTIVE: To compare validity, reliability, and responsiveness of generic and disease specific health-related quality of life (HRQOL) instruments in rheumatoid arthritis (RA). METHODS: Two samples of patients completed the Medical Outcomes Study Short Form-36 Health Survey (SF-36), EuroQol (EQ)-5D......, 15D, Rheumatoid Arthritis Quality of Life Scale (RAQoL), Health Assessment Questionnaire (HAQ), and visual analog scales (VAS) for pain, fatigue, and global RA. Validity (convergent, discriminant, and known-groups) was evaluated in a cross-section of 200 patients. Reliability was evaluated...

  13. Health related quality of life of Canary Island citizens

    Directory of Open Access Journals (Sweden)

    Lopez-Bastida Julio

    2010-11-01

    Full Text Available Abstract Background The aim of the study was to describe the health-related quality of life of Canarian population using information from the Canary Island Health Survey and three observational studies developed in the Canary Islands. Methods A descriptive analysis was carried out on a sample of 5.549 Canarian citizens using information from 2004 Canary Island Health Survey and three observational studies on Alzheimer's disease, Stroke and HIV. EQ-5 D was the generic tool used for revealing quality of life of people surveyed. Besides the rate of people reporting moderate or severe decrease in quality of life, TTO-index scores and visual analogue scale were used for assessing health related quality of life of people that suffer a specific diseases and general population. Results Self-perceived health status of citizens that suffer chronic diseases of high prevalence, identifies by the Canary Island Health Survey and other diseases such Alzheimer's disease, Stroke and HIV, independently examined in observational studies, are worse than self-perceived health of general population. Depression/anxiety and pain/discomfort were identified as the dimensions of the EQ-5 D with highest prevalence of problems. Alzheimer's disease and stroke were the illnesses with greater loss of quality of life. Conclusions Health related quality of life should be integrated into a set of information along with expectancy of life, incidence and prevalence of chronic diseases for developing health policy and planning health care activities The combination of information on health related quality of life from population health surveys with data from observational studies enlarges the sources of relevant information for setting health priorities and assessing the impact of health policies.

  14. Life satisfaction and health related quality of life during pregnancy and puerperium

    OpenAIRE

    Richart Martínez, Miguel; Cabrero García, Julio; Reig Ferrer, Abilio; Tosal Herrero, Beatriz; Orts Cortés, María Isabel

    2001-01-01

    While previous studies have defined ranges for health related quality of life (HRQOL) in other populations, there has been little attention to pregnant women. This study was undertaken to describe the evolution of the health related quality of life (HRQOL) and life satisfaction during pregnancy and puerperium. Poster submitted to the 22nd International Conference Stress and Anxiety Research Society (STAR), Palma de Mallorca, July, 12-14, 2001.

  15. Assessment of nutritional status and health-related quality of life before and after liver transplantation

    OpenAIRE

    García-Rodríguez, María Teresa; Piñón-Villar, María del Carmen; López-Calviño, Beatriz; Otero-Ferreiro, Alejandra; Suárez-López, Francisco; Gómez-Gutiérrez, Manuel; Pita-Fernández, Salvador

    2015-01-01

    Background Patients with chronic liver disease frequently suffer from malnutrition, together with a decline in their health-related quality of life. This study was carried out with the aim of evaluating the nutritional status, complications of medical and surgical care, anxiety, health-related quality of life and dependence level on basic and instrumental activities of daily living in pre- and post-liver transplant patients. Methods/Design A prospective observational study with follow-up of p...

  16. Evaluating clinically significant changes in health-related quality of life

    DEFF Research Database (Denmark)

    Norup, Anne; Kristensen, Karin Spangsberg; Poulsen, Ingrid;

    2015-01-01

    The objective of the study was to investigate change and predictors of change in health-related quality of life (HRQoL) in relatives of patients with severe traumatic brain injury (TBI) during rehabilitation, and to analyse associations between changes in HRQoL and symptoms of anxiety and...

  17. Health-related quality of life and cancer clinical trials

    OpenAIRE

    Osoba, David

    2011-01-01

    The measurement of patient-reported outcomes, including health-related quality of life, is a new initiative which has emerged and grown over the past four decades. Following the development of reliable and valid self-report questionnaires, health-related quality of life has been assessed in tens of thousands of patients and a wide variety of cancers. This review is based on a selection of data published in the last decade and is intended primarily for healthcare professionals. The assessments...

  18. 脑卒中后焦虑患者健康相关生存质量及其相关因素%Health-related quality of life and its related factors in Patients with Post-stroke anxiety

    Institute of Scientific and Technical Information of China (English)

    郝贵峰; 王帅华; 郑晓明; 朱崇田

    2014-01-01

    目的:探讨脑卒中后焦虑(PSA)患者健康相关生存质量(HRQOL)及其相关因素。方法:对317例不同临床类型缺血性脑卒中患者进行临床神经功能缺损程度、脑卒中专门化生存质量量表(SS-QOL)评分,对符合 PSA 诊断的患者进行 Hamilton 焦虑量表评分;分析与 HRQOL 相关的因素。结果:PSA 发生率为45.11±(143例);不同卒中类型患者 PSA 发生率差异无统计学意义,SS-QOL 评分由低到高依次为完全前循环梗死型、部分前循环梗死型、后循环梗死型及腔隙性梗死型,各型间差异有统计学意义(P ﹤0.05)。除语言因子外,PSA 组 SS-QOL 总分及其他各因子明显低非 PSA 组(P ﹤0.05或0.01);焦虑程度重、女性、﹤60岁、未婚或丧偶、高中以上文化程度、家庭月收入﹤2000元、神经功能缺损程度重和住院期间由护工照顾与 HRQOL 呈相关性。结论:PSA 发生率较高,性别、年龄、婚姻状况、文化程度、家庭月收入、神经功能缺损程度、照顾者及焦虑程度是影响 PSA 患者 HRQOL 的因素。%To investigate the health-related quality of life(HRQOL)and its influence fac-tors in patients with post-stroke anxiety(PSA). Method:Three hundred and seventeen patients with differ-ent clinical types ischemic stroke were assessed by the egree of clinical neural function defect scale and stroke-specific quality of life(SS-QOL)scale. The patients conformed PSA diagnostic criteria were evaluated by Ham-ilton anxiety scale. The associated factors of HRQOL were analyzed. Results:The PSA incidence among those patients was 45. 11±(143 cases),which among the different types of stroke was not significantly different. The scores from low to high were anterior circulation infarct,partial anterior circulation infarct,posterior circulation infarction and lacunar infarction and which had significant differences among the different types of stroke(P ﹤0. 05

  19. Oral health-related quality of life in Norwegian adults

    OpenAIRE

    2011-01-01

    Objectives The general aim of this thesis was to describe oral health-related quality of life (OHRQoL) in adults in the county of Nord-Trøndelag and in a national representative sample of Norwegian adults. A further goal was to study whether oral-health related quality of life is associated with clinical dental health, use of dental services, oral hygiene behaviours and demographic variables. The use of clinical measures only to assess the oral status of individuals has been criticized...

  20. Health related quality of life among insulin-dependent diabetics

    DEFF Research Database (Denmark)

    Aalto, A M; Uutela, A; Aro, A R

    1997-01-01

    This crossectional questionnaire study examined the associations of health factors and psychosocial factors with Health Related Quality of Life (HRQOL) in a sample of adult type I diabetic patients (n = 385). Health related quality of life was measured by the Finnish version of MOS SF-20....... Psychosocial measures were general social support, diabetes-specific social support, diabetes locus of control (DCL), self-efficacy, diabetes health beliefs and self-care practices. In multivariate analyses, limitations in physical functioning showed strong associations with perceived health (beta = -0.33, P...

  1. Health-Related Quality of Life in HIV-Infected Patients: The Role of Substance Use

    OpenAIRE

    Korthuis, P. Todd; ZEPHYRIN, Laurie C.; Fleishman, John A.; Saha, Somnath; Josephs, Joshua S.; McGrath, Moriah M.; Hellinger, James; Gebo, Kelly A.

    2008-01-01

    HIV infection and substance use disorders are chronic diseases with complex contributions to health-related quality of life (HRQOL). We conducted a cross-sectional survey of 951 HIV-infected adults receiving care at 14 HIV Research Network sites in 2003 to estimate associations between HRQOL and specific substance use among HIV-infected patients. HRQOL was assessed by multi-item measures of physical and role functioning, general health, pain, energy, positive affect, anxiety, and depression. ...

  2. Health related quality of life and psychological wellbeing in patients with hypertrophic cardiomyopathy.

    OpenAIRE

    Cox, S.; O'Donoghue, A. C.; McKenna, W. J.; STEPTOE, A

    1997-01-01

    OBJECTIVE: To assess the health related quality of life and psychological wellbeing of patients with hypertrophic cardiomyopathy, to correlate these with symptoms, clinical, and psychosocial factors. DESIGN: Questionnaire distributed to 171 hypertrophic cardiomyopathy patients aged at least 14 years, selected at random from a dataset of 480 patients. Assessments included the Short Form 36 (SF-36) Health Survey, the Hospital Anxiety and Depression questionnaire, and measures of adjustment, wor...

  3. Psychosocial Factors Contributing to Inflammatory Bowel Disease Activity and Health-Related Quality of Life

    OpenAIRE

    Faust, Alejandra H.; Halpern, Leslie F.; Danoff-Burg, Sharon; Cross, Raymond K.

    2012-01-01

    Objective: This study aimed to examine the contributions of coping and social constraint to disease activity and health-related quality of life (HRQOL) and to examine group differences in disease activity and HRQOL between patients with high versus low anxiety or depression symptoms in adults with inflammatory bowel disease (IBD). Methods: This study was a retrospective analysis in which disease activity was measured with either the Harvey-Bradshaw Index or the Simple Clinical Colitis Activit...

  4. Health-related quality of life in sarcoidosis

    NARCIS (Netherlands)

    Korenromp, Ingrid H.E.; Laar, van de Mart A.F.J.

    2014-01-01

    Purpose of review: The review presents an overview of the scientific publications in the field of health-related quality of life (HRQL) in sarcoidosis. Recent findings: Literature on HRQL in sarcoidosis is limited. HRQL was mainly used as a primary or secondary endpoint in intervention studies. Mo

  5. Measuring Health-Related Quality of Life: General Issues

    OpenAIRE

    Guyatt, Gordon H.

    1997-01-01

    Clinicians and policy makers recognize the importance of measuring health-related quality of life (HRQL) to make informed patient management and policy decisions. Self- or interviewer-administered questionnaires can be used to measure cross-sectional differences in quality of life among patients at a point in time (discriminative instruments) or longitudinal changes in HRQL within patients over time (evaluative instruments). Both discriminative and evaluative instruments must be valid (ie, me...

  6. Health related quality of life in patients with actinic keratosis

    DEFF Research Database (Denmark)

    Tennvall, Gunnel Ragnarson; Norlin, J M; Malmberg, I;

    2015-01-01

    BACKGROUND: Actinic keratosis (AK) is a common skin condition that may progress to non-melanoma skin cancer (NMSC). The disease may influence Health Related Quality of Life (HRQoL), but studies of HRQoL in patients with AK are limited. The purpose of the study was to analyze HRQoL in patients with......-center setting. Dermatologists assessed AK severity and patients completed: Actinic Keratosis Quality of Life Questionnaire (AKQoL), Dermatology Life Quality Index (DLQI), and EQ-5D-5 L including EQ-VAS. Differences between categorical subgroups were tested with Wilcoxon rank-sum test. The relationship between...

  7. Impact of cardiac rehabilitation on health related quality of life.

    LENUS (Irish Health Repository)

    Riaz, A

    2012-02-01

    Cardiac rehabilitation (CR) programs are recognized as integral part of the comprehensive care of patients with cardiovascular disease and are recommended as useful and effective (Class I) by the American Heart Association (AHA). In this study we used serial administration of the short form 36 (SF36) to evaluate patient\\'s response to CR in terms of improvement in Health related Quality of Life. A total of 49 patients were included in the analysis. There was a significant improvement observed after CR in the Physical Capacity Score (42.3 vs 49.9 p = 0.0005). There was no significant improvement in the Mental Capacity Score (54.8 vs 54.9 p = 0.96). We conclude that Cardiac Rehabilitation Program causes a significant improvement in the health related quality of life of patients by improving their physical health and well being but does not improve the mental capacity which is already at a healthy level before CR.

  8. Onychomycosis: Health-Related Quality of Life Considerations

    OpenAIRE

    Shaw, James W; Joish, Vijay N.; Stephen Joel Coons

    2002-01-01

    The symptoms of onychomycosis and their impact on personal appearance are important determinants of patients' perceptions of their own health. The effect of onychomycosis is greater on psychosocial than physical functioning and is directly related to the extent of nail involvement. This review identified a number of disease-targeted questionnaires that have been developed to assess the impact of onychomycosis and its treatment on health-related quality of life (HR-QOL). The instruments differ...

  9. Health-related quality of life outcomes after kidney transplantation

    OpenAIRE

    Mitterbauer Christa; Fiebiger Wolfgang; Oberbauer Rainer

    2004-01-01

    Abstract With the improvements in short and long term graft and patient survival after renal transplantation over the last two decades Health-Related Quality of Life (HRQL) is becoming an important additional outcome parameter. Global and disease specific instruments are available to evaluate objective and subjective QOL. Among the most popular global tools is the SF-36, examples of disease specific instruments are the Kidney Transplant Questionnaire (KTQ), the Kidney Disease Questionnaire (K...

  10. Health-related quality of life in early breast cancer

    DEFF Research Database (Denmark)

    Grønvold, Mogens

    2010-01-01

    thesis deals with scientific aspects and clinical results of a study aimed at assessing the impact of breast cancer (and its treatment) on the patients' quality of life. Studies such as this assessing the problems and symptoms experienced by the patients are often referred to as health-related quality of...... and we did not have a priori hypotheses for all these potential comparisons. Therefore, a staff survey involving experienced doctors and nurses was conducted in order to generate hypotheses that could be tested in the data from patients. We contacted 46 health care professionals and 36 (78%) responded...

  11. Heritability of health-related quality of life

    DEFF Research Database (Denmark)

    Steenstrup, Troels; Pedersen, Ole Birger; Hjelmborg, Jacob;

    2013-01-01

    Aim: The present study aims to estimate the relative importance of genetic and environmental factors for health-related quality of life (HRQL) measured by the 12-item Short-Form Health Survey (SF-12). Methods: The study was based on two Danish twin cohorts (46,417 twin individuals) originating from......-12 was completed by 29,619 individuals, which included 9,120 complete twin pairs. Overall, the best-fitting model explaining the variance of HRQL was the ACE model. The estimated heritability of the SF-12 was between 11% and 35%, whereas between 65% and 89% could be explained by unique environmental...

  12. Oral health related quality of life in diabetic patients.

    Science.gov (United States)

    Sadeghi, Rokhsareh; Taleghani, Ferial; Farhadi, Sareh

    2014-01-01

    Background and aims. Diabetic patients display an increased risk of oral disorders, and oral health related quality of life (OHRQL) might affect their management and treatment modalities. The aim of the present study was to determine OHRQL and associated parameters in patients with diabetes. Materials and methods. In this study two hundred patients were recruited from the diabetes clinic in Mustafa Khomeini Hospital in Tehran, Iran. OHRQL was assessed using Oral Health Impact Profile Questionnaire (OHIP-20). Also, another questionnaire was designed which contained questions regarding participants' knowledge about oral complications of diabetes and oral health behavior. OHRQL was categorized as low and good. Data were analyzed using logistic regression at P = 0.05. Results. Of the diabetic patients assessed, 77.5% were in good and 22.5% were in low categories of OHRQL. This quality was significantly associated with age (OR = 4.03, 95% CI = 1.63-11.29), knowledge about diabetes oral complications (OR = 18.17 95% CI = 4.42-158.6), educational level (OR = 26.31 95% CI = 4.2-1080.3), referred for dental visit by physician (OR = 3.16 95% CI = 1.48-6.69), frequency of brushing (OR = 10.29 95% CI = 3.96-31.2) and length of time diagnosed with diabetes (OR = 6.21 95% CI = 2.86-13.63). Conclusion. Oral health related quality of life was not negatively affected by diabetes mellitus in the assessed sample. PMID:25587385

  13. The Association between Vitamin D and Health-Related Quality of Life in Korean Adults

    Science.gov (United States)

    Kim, Ji Sun; Baek, Jin Kyung; Cho, Ho Jin; Kim, Ye Seul

    2016-01-01

    Background We examined the relationship between vitamin D status and health-related quality of life, and explored other related factors in the general Korean population. Methods We used data from the 2007–2012 Korea National Health and Nutrition Examination Survey on 14,104 adults, aged 20–49 years, who had consented to serum vitamin D measurement and answered health-related quality of life questions. EuroQol-5 was used for measurement. Serum vitamin D levels were measured at intervals of 0–9.99, 10–19.99, 20–29.99, and ≥30 ng/mL. Results Participants with higher serum vitamin D (serum 25-hydroxyvitamin D) levels were significantly less likely to report problems with depression and anxiety. After adjustment for age, gender, income level, education level, marital status, alcohol consumption, smoking status, and the existence of depressive disorders, the odds ratio for reporting a problem with depression and anxiety was 0.60 (95% confidence interval [CI], 0.39–0.91). The odds ratio for the prevalence of any problem was 0.69 (95% CI, 0.53–0.89) before adjustment, but was not statistically significant after adjustment. No significant associations were observed for problems with mobility, self-care, usual activity, or pain and discomfort. Conclusion This is the first study to examine the associations between vitamin D and health-related quality of life for the general Korean population. Vitamin D status was not significantly associated with the dimensions of EuroQol-5 except for depression and anxiety problems. PMID:27468340

  14. Health-related quality of life assessment in Indonesian childhood acute lymphoblastic leukemia

    Directory of Open Access Journals (Sweden)

    Sutaryo

    2008-11-01

    Full Text Available Abstract Background Most studies on Health-related Quality of Life (HRQOL in children with cancer were conducted in developed countries. The aims of this study were to assess the HRQOL in childhood acute lymphoblastic leukemia (ALL patients in Indonesia and to assess the influence of demographic and medical characteristics on HRQOL. Methods After cultural linguistic validation, a cross-sectional study of HRQOL was conducted with childhood ALL patients and their guardians in various phases of treatment using the Pediatric Quality of Life Inventory™ (PedsQL™ 4.0 Generic Core Scale and the Pediatric Quality of Life Inventory™ (PedsQL™ 3.0 Cancer Module. Results Ninety-eight guardians and 55 patients participated. The internal consistency of both scales ranged from 0.57 to 0.92. HRQOL of Indonesian patients was comparable with those in developed countries. There were moderate to good correlations between self-reports and proxy-reports, however guardians tended to report worse HRQOL than patients. Children of the 2–5 year-group significantly had more problems in procedural anxiety, treatment anxiety and communication subscales than in older groups (p Conclusion Younger children had more problems in procedural anxiety, treatment anxiety and communication subscales. Therefore, special care during intervention procedures is needed to promote their normal development. Psychosocial support should be provided to children and their parents to facilitate their coping with disease and its treatment.

  15. Impact of Anxiety on Quality of Life in Parkinson's Disease

    Directory of Open Access Journals (Sweden)

    Kristine K. Hanna

    2012-01-01

    Full Text Available In Parkinson's disease (PD, both the patient and the health care provider look for ways to preserve the patient's quality of life. Many studies focus on the impact of depression and motor disability on poor life quality but neglect to examine the role of anxiety. We investigated the impact of anxiety and depression on health-related quality of life in PD, using the Parkinson's Disease Quality of Life measure (PDQ-39. Symptoms of anxiety, more than depression, cognitive status, or motor stage, significantly affected quality of life in 38 nondemented patients with mild-to-moderate motor disability. Stepwise regression analyses revealed that anxiety explained 29% of the variance in the PDQ-39 sum score, and depression explained 10% of the variance beyond that accounted for by anxiety. The findings suggest that primary management of anxiety as well as depression may be important to optimizing the quality of life of PD patients.

  16. Health-related quality of life outcomes after kidney transplantation

    Directory of Open Access Journals (Sweden)

    Mitterbauer Christa

    2004-01-01

    Full Text Available Abstract With the improvements in short and long term graft and patient survival after renal transplantation over the last two decades Health-Related Quality of Life (HRQL is becoming an important additional outcome parameter. Global and disease specific instruments are available to evaluate objective and subjective QOL. Among the most popular global tools is the SF-36, examples of disease specific instruments are the Kidney Transplant Questionnaire (KTQ, the Kidney Disease Questionnaire (KDQ and the Kidney Disease-Quality of Life (KDQOL. It is generally accepted that HRQL improves dramatically after successful renal transplantation compared to patients maintained on dialysis treatment but listed for a transplant. It is less clear however which immunosuppressive regimen confers the best QOL. Only few studies compared the different regimens in terms of QOL outcomes. Although limited in number, these studies seem to favour non-cyclosporine based protocols. The main differences that could be observed between patients on cyclosporine versus tacrolimus or sirolimus therapy concern the domains of appearance and fatigue. This may be explained by two common adverse effects occurring under cyclosporine therapy, gingival hyperplasia and hair growth. Another more frequently occurring side effect under calcineurin inhibitor therapy is tremor, which may favour CNI free protocols. This hypothesis, however, has not been formally evaluated in a randomised trial using HRQL measurements. In summary HRQL is becoming more of an issue after renal transplantation. Whether a specific immunosuppressive protocol is superior to others in terms of HRQL remains to be determined.

  17. Health related quality of life in Malaysian children with thalassaemia

    Directory of Open Access Journals (Sweden)

    Jones Georgina L

    2006-07-01

    Full Text Available Abstract Background Health Related Quality of Life (HRQoL studies on children with chronic illness such as thalassaemia are limited. We conducted the first study to investigate if children with thalassaemia have a lower quality of life in the four dimensions as measured using the PedsQL 4.0 generic Scale Score: physical, emotional, social and role (school functioning compared to the healthy controls allowing for age, gender, ethnicity and household income. Methods The PedsQL 4.0 was administered to children receiving blood transfusions and treatments at Hospital Kuala Lumpur, Malaysia using PedsQL 4.0 generic Scale Score. Accordingly, the questionnaire was also administered to a control group of healthy school children. Socio-demographic data were also collected from patients and controls using an interview schedule designed for the study. Results Of the 96 thalassaemia patients approached, 78 gave consent to be interviewed giving a response rate of 81.3%. Out of 235 healthy controls approached, all agreed to participate giving a response rate of 100%. The mean age for the patients and schoolchildren is 11.9 and 13.2 years respectively. The age range for the patients and the schoolchildren is between 5 to 18 years and 7 to 18 years respectively. After controlling for age and demographic background, the thalassaemia patients reported having significantly lower quality of life than the healthy controls. Conclusion Thalassaemia has a negative impact on perceived physical, emotional, social and school functioning in thalassaemia patients which was also found to be worse than the children's healthy counterparts. Continuing support of free desferal from the Ministry of Health should be given to these patients. More understanding and support especially from health authorities, school authorities and the society is essential to enhance their quality of life.

  18. Health-related quality of life and expectations of patients before surgical treatment of lumbar stenosis

    Directory of Open Access Journals (Sweden)

    Lílian Maria Pacola

    2014-03-01

    Full Text Available OBJECTIVE: To evaluate the expectations of patients awaiting surgical treatment of lumbar canal stenosis and the association of Health-Related Quality of Life (HRQoL with symptoms of anxiety and depression. METHODS: The sample included 49 patients from a university hospital. HRQoL was assessed by the Oswestry Disability Index (ODI and 36-item Medical Outcomes Survey Short Form (SF-36 and symptoms of anxiety and depression by the Hospital Anxiety and Depression Scale (HADS. Expectations were investigated by means of questions used in international studies. Data were analyzed descriptively and by Student's t test. RESULTS: The mean time of disease progression was 34.5 months, the mean age was 58.8 years and 55.1% of the patients were women. Most patients had the expectation of improving with surgical treatment and 46.9% expected to be "much better" with regard to leg pain, walking ability, independence in activities and mental well being. The scores of anxiety and depression were respectively, 34.7% and 12.2%. We observed statistically significant differences between the groups with and without anxiety in the domains: General Health, Mental Health, and Vitality. Between the groups with and without depression there were statistically significant differences in the General Health and Mental Health domains. CONCLUSION: Patients showed great expectation to surgical treatment and the symptoms of anxiety and depression were related to some domains of HRQoL. Thus, the study contributes to broaden our knowledge and we can therefore guide the patients as to their expectations with respect to the real possibilities arising from surgery.

  19. Health-related quality of life in patients with indolent and aggressive non-Hodgkin lymphoma

    Directory of Open Access Journals (Sweden)

    Eliza M. Alawi

    2016-12-01

    Full Text Available Indolent and aggressive non-Hodgkin lymphomas (NHL are common types of hematologic malignancies but their effect on quality of life (QoL is understudied. In particular, the relation between different aspects of QoL and cognitive impairments and coping styles is relevant for individualized physical and mental health care. We studied emotional, physical, and subjective well-being in relation to cognitive capacities and coping style in 100 patients with NHL (44 females, age 61.3 ± 13.6. Questionnaires assessed health-related QoL (Functional Assessment of Cancer Therapy (FACT, affect (Hospital Anxiety and Depression Scale, Positive and Negative Affective Schedule, distress (Distress Thermometer, and locus of control; semi-structured interviews targeted subjective QoL (Schedule for Evaluating the Individual Quality of Life and cognitive impairments (Test for Early Detection of Dementia with Differentiation from Depression. Indolent NHL (n = 44 yielded better health-related QOL and positive affect and less anxiety than the aggressive type (n = 55; FACT: t(97 = 1.90, p = .028, anxiety: t(97 = −1.9, p = .030; positive affect: t(96 = 2.01, p = .023. In a factor analysis, physical and affective scales loaded on an emotional and physical well-being factor, which differed between the groups. Further, cognitive capacities and locus of control contributed to subjective QoL and reported distress. Emotional and physical scales assess QoL in NHL. However, cognitive impairments or external locus of control may hamper reporting of distress. Psychosocial support should specifically target at-risk patients.

  20. Systematic review of health-related quality of life models

    Directory of Open Access Journals (Sweden)

    Bakas Tamilyn

    2012-11-01

    Full Text Available Abstract Background A systematic literature review was conducted to (a identify the most frequently used health-related quality of life (HRQOL models and (b critique those models. Methods Online search engines were queried using pre-determined inclusion and exclusion criteria. We reviewed titles, abstracts, and then full-text articles for their relevance to this review. Then the most commonly used models were identified, reviewed in tables, and critiqued using published criteria. Results Of 1,602 titles identified, 100 articles from 21 countries met the inclusion criteria. The most frequently used HRQOL models were: Wilson and Cleary (16%, Ferrans and colleagues (4%, or World Health Organization (WHO (5%. Ferrans and colleagues’ model was a revision of Wilson and Cleary’s model and appeared to have the greatest potential to guide future HRQOL research and practice. Conclusions Recommendations are for researchers to use one of the three common HRQOL models unless there are compelling and clearly delineated reasons for creating new models. Disease-specific models can be derived from one of the three commonly used HRQOL models. We recommend Ferrans and colleagues’ model because they added individual and environmental characteristics to the popular Wilson and Cleary model to better explain HRQOL. Using a common HRQOL model across studies will promote a coherent body of evidence that will more quickly advance the science in the area of HRQOL.

  1. Health-Related Quality of Life in Morphea

    Science.gov (United States)

    Klimas, N.K.; Shedd, A.D.; Bernstein, I.H.; Jacobe, H.

    2014-01-01

    Background Little is known about the health-related quality of life (HRQOL) of patients with morphea, and previous studies have yielded conflicting results. Objectives To determine the impact of morphea on HRQOL and clinical and demographic correlates of HRQOL in adults. Methods Cross sectional survey (n=73) of Morphea in Adults and Children (MAC) cohort. Results Morphea impairs HRQOL in adults. Patients were most impaired by emotional well-being and concerns that the disease will progress to their internal organs. Patients with morphea had worse skin-specific HRQOL than those with non-melanoma skin cancer, vitiligo, and alopecia (lowest P <.0001). Study subjects had significantly worse global HRQOL scores than the general U.S. population for all subscales (all P ≤.004) with the exception of bodily pain. Comorbidity (r =.35-.51, P ≤ .0029 -.0001) and symptoms of pruritus (r =.38 -.64, P ≤.001-.0001) and pain (r =.46-.74, P <.0001) were associated with impairment in multiple domains of skin-specific and global HRQOL. Physician-based measures of disease severity correlated with patient-reported HRQOL. Conclusion Patients with morphea have negative impact on HRQOL particularly if symptoms (pruritus and pain) or concerns regarding internal manifestations are present. Providers should be aware of this when evaluating and treating patients. PMID:25483169

  2. Health related quality of life and influencing factors among welders.

    Directory of Open Access Journals (Sweden)

    Jingxiang Qin

    Full Text Available BACKGROUND: Occupational exposure to welding fumes is a serious occupational health problem all over the world. Welders are exposed to many occupational hazards; these hazards might cause some occupational diseases. The aim of the study was to assess the health related quality of life (HRQL of electric welders in Shanghai China and explore influencing factors to HRQL of welders. METHODS: 301 male welders (without pneumoconiosis and 305 non-dust male workers in Shanghai were enrolled in this study. Short Form-36 (SF-36 health survey questionnaires were applied in this cross-sectional study. Socio-demographic, working and health factors were also collected. Multiple stepwise regress analysis was used to identify significant factors related to the eight dimension scores. RESULTS: Six dimensions including role-physical (RP, bodily pain (BP, general health (GH, validity (VT, social function (SF, and mental health (MH were significantly worse in welders compared to non-dust workers. Multiple stepwise regress analysis results show that native place, monthly income, quantity of children, drinking, sleep time, welding type, use of personal protective equipment (PPE, great events in life, and some symptoms including dizziness, discomfort of cervical vertebra, low back pain, cough and insomnia may be influencing factors for HRQL of welders. Among these factors, only sleep time and the use of PPE were salutary. CONCLUSIONS: Some dimensions of HRQL of these welders have been affected. Enterprises which employ welders should take measures to protect the health of these people and improve their HRQL.

  3. Health-related quality of life and mental distress in patients with partial deafness: preliminary findings.

    Science.gov (United States)

    Cieśla, Katarzyna; Lewandowska, Monika; Skarżyński, Henryk

    2016-03-01

    The aim of the study was to evaluate mental distress and health-related quality of life in patients with bilateral partial deafness (high-frequency sensorineural hearing loss) before cochlear implantation, with respect to their audiological performance and time of onset of the hearing impairment. Thirty-one patients and 31 normal-hearing individuals were administered the Beck Depression Inventory (BDI), the State-Trait-Anxiety-Inventory (STAI) and the World Health Organization Quality of Life-BREF questionnaire (WHOQOL-BREF). Patients also completed the Nijmegen-Cochlear-Implant-Questionnaire (NCIQ), a tool for evaluation of quality of life related to hearing loss. Patients revealed increased depressive and anxiety symptoms, as well as decreased health-related quality of life (psychological health, physical health), in comparison with their healthy counterparts (t tests, p deafness (p tone thresholds at 1 and 2 kHz with subtracted threshold at 0.5 kHz) and better audiometric speech detection, between audiometric thresholds and the subjectively rated sound perception (NCIQ), as well as left-ear audiometric word recognition scores and the subjectively perceived ability to recognize advanced sounds (NCIQ). In addition, a longer duration of postlingual deafness, as well as a younger age at the onset were both related to worse speech detection thresholds. The results of the study provide evidence that successful rehabilitation in patients with partial deafness might have to go beyond the standard speech therapy. Enhancement of the regular diagnostic assessment with additional psychological tools is highly recommended. Further investigation is required as to the role of functional residual hearing, hearing aid use and tinnitus, in relation to future outcomes of cochlear implantation. PMID:26242252

  4. Valuation of Child Health-Related Quality of Life in the United States.

    Science.gov (United States)

    Craig, Benjamin M; Greiner, Wolfgang; Brown, Derek S; Reeve, Bryce B

    2016-06-01

    Many economic analyses fail to incorporate evidence on child health-related quality of life because of a paucity of quality-adjusted life year (QALY) estimates. This health valuation study is the first to summarize the EQ-5D-Y on a QALY scale. Drawn from a nationally representative panel, 5207 adult respondents were asked to choose between two losses in child health-related quality of life. Based on their choices, a 1-year increase in child pain/discomfort from 'some' to 'a lot' equals a loss of 4 QALYs (95% CI, 3.8-4.4). Likewise, a 1-year increase in child anxiety/depression from 'a bit' to 'very worried, sad, or unhappy' equals a loss of 2 QALYs (95% CI, 1.9-2.2). These findings enable the integration of child-reported outcomes with adult preferences to inform economic analysis. Results inform both clinical practice and resource allocation decisions by enhancing understanding of difficult tradeoffs in child-reported outcomes. Copyright © 2015 John Wiley & Sons, Ltd. PMID:25926161

  5. Health-related quality of life in dermatology: measurement, interpretation and application

    OpenAIRE

    Rie, de, M.A.; Sprangers, M.A.G.; Korte, de, P.A.J.; Spuls, P.I.; Lindeboom, R.; Prinsen, C.A.C.

    2013-01-01

    This thesis consists of three parts. The aim of part one, ‘Measurement of health-related quality of life in dermatology’, was to contribute to the quality of health-related quality of life (HRQoL) measurement in dermatological research and clinical practice. The aim of part two, ‘Interpretation of health-related quality of life scores’, was to facilitate the interpretation of Skindex-29 scores and score differences. The aim of part three, ‘Health-related quality of life application in clinica...

  6. Testing the applicability of a model of oral health-related quality of life

    OpenAIRE

    Camila Mello dos Santos; Roger Keller Celeste; Juliana Balbinot Hilgert; Fernando Neves Hugo

    2015-01-01

    The aim of this study was to test Wilson & Cleary’s conceptual model of the direct and mediated pathways between clinical and non-clinical variables in relation to oral health-related quality of life. A random sample of 578 older people was evaluated. Wilson & Cleary’s conceptual model was tested using structural equations modeling including: biological variables, symptom status, functional health, oral health perceptions, oral health-related quality of life. Oral health-related quality of li...

  7. Calidad de vida relacionada con la salud: Elementos conceptuales Health related quality of life: Conceptual elements

    Directory of Open Access Journals (Sweden)

    ALFONSO URZÚA M

    2010-03-01

    Full Text Available Health related Quality of Life is commonly used as a subjective assessment of health status. This article is a review of theoretical concepts about quality of life. Some models are proposed and general issues about it measurement are analyzed. Information about health related quality of life helps for decision making about health care both in clinical and public care settings.

  8. Health Related Quality Management Values and Key Principles of Communicative Leadership - Are They the Same?

    OpenAIRE

    Ingela Backstrom; Pernilla Ingelsson; Catrin Johansson

    2014-01-01

    The purpose of this paper is to compare health related values within Quality Management with Key Principles of Communicative Leadership in order to see if Communicative leaders also promote healthy co-workers.  A literature review was conducted within the area of Communicative Leadership and within the values of health related Quality Management. The principles within Communicative leadership were compared with the underlying dimensions within the health related values ‘Leadership Commitment’...

  9. Mental Health and Health-Related Quality of Life in Multiple Sclerosis Caregivers in Mexico

    Science.gov (United States)

    Stern, Marilyn; Arelis, Adriana Aguayo; Islas, Miguel Angel Macias; Barajas, Brenda Viridiana Rábago

    2016-01-01

    Background: Multiple sclerosis (MS) rates are increasing in Latin America, and caregiving for an individual with MS is associated with poorer mental and physical health outcomes. No existing research has examined the relation between mental health and health-related quality of life (HRQOL) in MS caregivers in Latin America. Methods: The present study examined the association between mental health (Patient Health Questionnaire-9, Satisfaction with Life Scale, Rosenberg Self-esteem Scale, State-Trait Anxiety Inventory) and HRQOL (36-item Short Form Health Status Survey) in 81 Mexican MS caregivers. Results: A canonical correlation analysis uncovered a large, significant overall association between mental health and HRQOL, with 52.7% of the variance shared between the two sets of constructs. When individual canonical loadings were examined in this analysis, the most substantial pattern that emerged was between depression and general health. Four regressions controlling for demographic variables found that HRQOL uniquely accounted for 19.0% of the variance in caregiver anxiety, 32.5% in depression, 13.5% in satisfaction with life, and 14.3% in self-esteem. Conclusions: These findings demonstrated a strong association between HRQOL and mental health, which points to directions for future studies on interventions for MS caregivers, particularly in Mexican and other Latino populations. PMID:26917994

  10. Anxiety and Quality of Life: Clinically Anxious Children with and without Autism Spectrum Disorders Compared

    Science.gov (United States)

    van Steensel, Francisca J. A.; Bogels, Susan M.; Dirksen, Carmen D.

    2012-01-01

    Comorbid anxiety disorders are common in children with autism spectrum disorders (ASD). However, studies comparing children with ASD to clinically anxious children are rare. This study investigated anxiety problems and health-related quality of life in children with high-functioning ASD and comorbid anxiety disorders (referred to as the ASD…

  11. Health-related quality of life in adult survivors of childhood sarcoidosis

    DEFF Research Database (Denmark)

    Milman, Nils; Svendsen, Claus Bo; Hoffmann, Anne Lisbeth

    2009-01-01

    AIM: To describe health-related quality of life (hrQOL) in adult subjects who had sarcoidosis in childhood. METHODS: Forty-six children (24 boys), all ethnic Danes......AIM: To describe health-related quality of life (hrQOL) in adult subjects who had sarcoidosis in childhood. METHODS: Forty-six children (24 boys), all ethnic Danes...

  12. Child Health-Related Quality of Life and Parental Social Capital in Greece: An Exploratory Study

    Science.gov (United States)

    El-Dardiry, Giulia; Dimitrakaki, Christine; Tzavara, Chara; Ravens-Sieberer, Ulrike; Tountas, Yannis

    2012-01-01

    In this paper, we examined dimensions of child health-related quality of life in Greece in relation to parental assessments of neighbourhood social capital and social support networks. For the analysis, two main measures were used: (1) child self-reported health-related quality of life in ten dimensions, as measured by the KIDSCREEN questionnaire;…

  13. Health-related quality of life in the elderly three years after percutaneous coronary intervention

    DEFF Research Database (Denmark)

    Panasewicz, Anna; Pedersen, Susanne S.; Veenhuis, Stefanie J G;

    2013-01-01

    Long-term health-related quality of life (HRQOL) in the elderly after percutaneous coronary intervention (PCI) is unknown. We 1) compared HRQOL of elderly (≥70 years) with younger patients (......Long-term health-related quality of life (HRQOL) in the elderly after percutaneous coronary intervention (PCI) is unknown. We 1) compared HRQOL of elderly (≥70 years) with younger patients (...

  14. Poster: Oral-Health-Related Quality of Life among Danish adults

    DEFF Research Database (Denmark)

    Christensen, Lisa Bøge; Hede, Børge; Fiehn, Nils-Erik;

    Danish cities. Age 18-96 years (average 54) Structured interviews (from main study and dental study) and clinical oral examination Oral-health-related quality of life measured by a 10 item index Non-parametric statistical methods, chi-square, simple and multivariate logistic regression Conclusions...... Regular dental visits and high number of natural teeth are determinants for high level of oral-health-related quality of life Untreated caries, wearing dentures and high caries experience are determinants for reduced oral-health-related quality of life Results 33 persons were edentulous, 7 % wore dentures...... , mean DMFS = 62 88% were regular users of dental care 24 % reported oral-health-related quality of life problems 6 % reported score of 3 or more oral-health-related quality of life problems (maximum score = 30) Most frequent problems because of appearance of teeth (or dentures) : Feeling embarrassed (13...

  15. Hepatitis C virus infection and health-related quality of life

    Institute of Scientific and Technical Information of China (English)

    Piero Amodio; Laura Salari; Sara Montagnese; Sami Schiff; Daniele Neri; Tonino Bianco; Lina Minazzato

    2012-01-01

    Hepatitis C virus (HCV) hepatitis and other diseases related to HCV,such as cryoglobulinemia,lymphoma and renal failure,impair health-related quality of life (HRQoL).In addition,HCV per se might directly influence HRQoL via colonization of microglia in the brain or,indirectly,via the effect of systemic inflammatory cytokines which,in turn,can trigger brain interleukin production.The treatment of HCV-related disorders with interferon (IFN) has an effect on HRQoL.Initially,IFN causes a transient deterioration of HRQoL,due to the induction of depression and other side effects of treatment.Subsequently,the subjects who obtain a sustained virologic response experience an improvement in HRQoL.Only rarely does interferon treatment causes permanent detrimental effects on HRQoL,due to residual psychiatric or neurologic side effects.Liver transplantation is the only treatment for end-stage HCV-related liver disease.HRQoL generally improves massively a few months after transplantation,except in the case of serious complications of the transplant procedure.Furthermore,high levels of anxiety and neuroticism pre-transplant are associated with lower HRQoL one year after transplant.Additionally,six months after transplant,patients with HCV who experience virologic recurrence show significantly greater depression,anxiety,phobic anxiety,and paranoid ideation than anti-HCV-negative patients.In conclusion,optimal care for the overall well-being of patients with HCV infection requires adequate knowledge of their neurological and psychological status.

  16. Smoking and health-related quality of life in English general population: implications for economic evaluations

    Directory of Open Access Journals (Sweden)

    Vogl Matthias

    2012-03-01

    Full Text Available Abstract Background Little is known as to how health-related quality of life (HRQoL when measured by generic instruments such as EQ-5D differ across smokers, ex-smokers and never-smokers in the general population; whether the overall pattern of this difference remain consistent in each domain of HRQoL; and what implications this variation, if any, would have for economic evaluations of tobacco control interventions. Methods Using the 2006 round of Health Survey for England data (n = 13,241, this paper aims to examine the impact of smoking status on health-related quality of life in English population. Depending upon the nature of the EQ-5D data (i.e. tariff or domains, linear or logistic regression models were fitted to control for biology, clinical conditions, socio-economic background and lifestyle factors that an individual may have regardless of their smoking status. Age- and gender-specific predicted values according to smoking status are offered as the potential 'utility' values to be used in future economic evaluation models. Results The observed difference of 0.1100 in EQ-5D scores between never-smokers (0.8839 and heavy-smokers (0.7739 reduced to 0.0516 after adjusting for biological, clinical, lifestyle and socioeconomic conditions. Heavy-smokers, when compared with never-smokers, were significantly more likely to report some/severe problems in all five domains - mobility (67%, self-care (70%, usual activity (42%, pain/discomfort (46% and anxiety/depression (86% -. 'Utility' values by age and gender for each category of smoking are provided to be used in the future economic evaluations. Conclusion Smoking is significantly and negatively associated with health-related quality of life in English general population and the magnitude of this association is determined by the number of cigarettes smoked. The varying degree of this association, captured through instruments such as EQ-5D, may need to be fed into the design of future economic

  17. Subjective food intake ability related to oral health-related quality of life and psychological health.

    Science.gov (United States)

    Choi, S-H; Kim, J-S; Cha, J-Y; Lee, K-J; Yu, H-S; Hwang, C-J

    2016-09-01

    Reduced food intake ability can restrict an individual's choice of foods and might have a significant impact on the individual's quality of life and mental health. The aim of this study was to evaluate the correlations between self-reported masticatory ability and oral health-related quality of life (OHRQOL) and psychological health. The study included 72 (26 men, 46 women) adults with a mean age of 26·4 ± 8·6 years. Each participant completed the key subjective food intake ability (KFIA) test for five key foods, the Korean version of the Oral Health Impact Profile-14 (OHIP-14K) and three questionnaires for measuring anxiety, depression and self-esteem. The participants were distributed into two groups by sex (a mean age of 23·9 ± 5·2 for men and 27·9 ± 9·8 for women) and by the median KFIA score. There were no significant differences in any of the variables according to sex. Thirty-two participants (12 men, 20 women) in the lower KFIA group had a higher total OHIP-14K (P depression level (P women) in the higher KFIA group. As the KFIA decreased, OHRQOL worsened (P depression increased (P depression level. PMID:27224265

  18. From headache to tumour: An examination of health anxiety, health-related Internet use and 'query escalation'.

    Science.gov (United States)

    Singh, Karmpaul; Brown, Richard J

    2016-09-01

    The current study aimed to explore the phenomenon of disease-related 'query escalation' in high/low health anxious Internet users (N = 40). During a 15-minute health-related Internet search, participants rated their anxiety and the perceived seriousness of information on each page. Post-search interviews determined the reasons for, and effects of, escalating queries to consider serious diseases. Both groups were found to be significantly more anxious after escalating queries. The high group was significantly more likely to escalate queries. Evaluating personal relevance of material was the main reason for escalations and moderated anxiety post-escalation. We conclude that searching for online disease information can increase anxiety, particularly for people worried about their health. PMID:25706333

  19. Dental Implants Improve Oral Health Related Quality of Life

    Czech Academy of Sciences Publication Activity Database

    Seydlová, M.; Kříž, P.; Dostálová, T.; Valenta, Zdeněk; Chleborád, K.; Zvárová, Jana

    Marmara University, 2010. s. 30-31. [Methodological Issues in Oral Health Research: Intervention Studies. International Meeting /4./. 21.03.2010-23.03.2010, Istanbul] Institutional research plan: CEZ:AV0Z10300504 Keywords : dental implants * oral health * quality of life Subject RIV: FF - HEENT, Dentistry

  20. The MacNew Heart Disease Health-Related Quality of Life Questionnaire: A Scandinavian Validation Study

    OpenAIRE

    Alphin, Shan; Höfer, Stefan; Perk, Joep; Slørdahl, Stig; Zwisler, Ann-Dorthe Olsen; Oldridge, Neil

    2014-01-01

    The aim of this study is to validate the Danish, Norwegian and Swedish versions of the self-administered MacNew Heart Disease Health-related Quality of Life questionnaire in patients with ischemic heart disease. The MacNew questionnaire, the Short Form SF-36, and the Hospital Anxiety and Depression Scale were completed at baseline by 976 patients (Denmark n = 353, Norway n = 328, Sweden n = 295) with a diagnosis of angina (n = 335), myocardial infarction (n = 352), or heart failure (n = 289)....

  1. Health related quality of life in Critically ill Patients A study of health related quality of life in critically ill patients admitted on the Intensive Care

    NARCIS (Netherlands)

    J.G.M. Hofhuis (José)

    2008-01-01

    textabstractHealth related quality of life (HRQOL) is a relevant outcome measure for patients admitted to the intensive care unit (ICU). Long term outcome for physical and psychological factors, functional status and social interactions are becoming more and more important both for doctors and nurse

  2. Oral health-related quality of life and periodontal status

    OpenAIRE

    Ng, SKS; Leung, WK

    2005-01-01

    Background: As patient-centered approaches become more popular, increasing attention is being given to assess the effects of various human health situations on an individual's overall quality of life (QoL). Measures have been used in dentistry to study the effects of orthodontic treatment and oral surgery, but so far little has been reported about the effects of periodontal disease. Objective: This study assessed the impact of periodontal health status on QoL. Methods: A subsample of 767 subj...

  3. Health-related quality of life outcomes after cholecystectomy

    Institute of Scientific and Technical Information of China (English)

    Amedeo Carraro; Dania EI Mazloum; Florian Bihl

    2011-01-01

    Gallbladder diseases are very common in developed countries. Complicated gallstone disease represents the most frequent of biliary disorders for which surgery is regularly advocated. As regards, cholecystectomy represents a common abdominal surgical intervention; it can be performed as either an elective intervention or emergency surgery, in the case of gangrene, perforation, peritonitis or sepsis. Nowadays, the laparoscopic approach is preferred over open laparotomy. Globally, numerous cholecystectomies are performed daily; however, little evidence exists regarding assessment of post-surgical quality of life (QOL) following these interventions. To assess post-cholecystectomy QOL, in fact, documentation of high quality care has been subject to extended discussions, and the use of patient-reported outcome satisfaction for quality improvement has been advocated for several years. However, there has been little research published regarding QOL outcomes following cholecystectomy; in addition, much of the current literature lacks systematic data on patient-centered outcomes. Then, although several tools have been used to measure QOL after cholecystectomy, difficulty remains in selecting meaningful parameters in order to obtain reproducible data to reflect postoperative QOL. The aim of this study was to review the impact of surgery for gallbladder diseases on QOL. This review includes Medline searches of current literature on QOL following cholecystectomy. Most studies demonstrated that symptomatic patients profited more from surgery than patients receiving an elective intervention. Thus, the gain in QOL depends on the general conditions before surgery, and patients without symptoms profit less or may even have a reduction in QOL.

  4. Opposite poles: A comparison between two Spanish regions in health-related quality of life, with implications for health policy

    Directory of Open Access Journals (Sweden)

    López-Valcárcel Beatriz G

    2010-09-01

    Full Text Available Abstract Background Although health is one of the main determinants of the welfare of societies, few studies have evaluated health related quality of life in representative samples of the population of a region or a country. Our aim is to describe the health-related quality of life of the inhabitants of two quite different Spanish regions (Canary Islands and Catalonia and to compare the prevalence of health problems between age-sex groups. Methods We use data obtained from the 2006 Health Survey of Catalonia and the 2004 Canary Islands Health Survey. With an ordinal composite variable measuring HRQOL we identify the association of characteristics of individuals with self-reported quality of life and test for differences between the regions. Results The prevalence of problems in the five EQ-5 D dimensions increases with age and is generally higher for women than for men. The dimension with the highest prevalence of problems is "anxiety/depression", and there is noteworthy the extent of discomfort and pain among Canary Island women. Education, especially among the elderly, has an important effect on health-related quality of life. Conclusions There are substantial structural and compositional differences between the two regions. Regional context is a significant factor, independent of the compositional differences, and the effects of context are manifest above all in women. The findings show the importance of disease prevention and the need for improving the educational level of the population in order to reduce health inequalities.

  5. Epidemiology and Health-Related Quality of Life in Hypoparathyroidism in Norway

    Science.gov (United States)

    Løvås, Kristian; Debowska, Aleksandra; Eriksen, Erik F.; Evang, Johan A.; Fossum, Christian; Fougner, Kristian J.; Holte, Synnøve E.; Lima, Kari; Moe, Ragnar B.; Myhre, Anne Grethe; Kemp, E. Helen; Nedrebø, Bjørn G.; Svartberg, Johan; Husebye, Eystein S.

    2016-01-01

    Objective: The epidemiology of hypoparathyroidism (HP) is largely unknown. We aimed to determine prevalence, etiologies, health related quality of life (HRQOL) and treatment pattern of HP. Methods: Patients with HP and 22q11 deletion syndrome (DiGeorge syndrome) were identified in electronic hospital registries. All identified patients were invited to participate in a survey. Among patients who responded, HRQOL was determined by Short Form 36 and Hospital Anxiety and Depression scale. Autoantibodies were measured and candidate genes (CaSR, AIRE, GATA3, and 22q11-deletion) were sequenced for classification of etiology. Results: We identified 522 patients (511 alive) and estimated overall prevalence at 102 per million divided among postsurgical HP (64 per million), nonsurgical HP (30 per million), and pseudo-HP (8 per million). Nonsurgical HP comprised autosomal dominant hypocalcemia (21%), autoimmune polyendocrine syndrome type 1 (17%), DiGeorge/22q11 deletion syndrome (15%), idiopathic HP (44%), and others (4%). Among the 283 respondents (median age, 53 years [range, 9–89], 75% females), seven formerly classified as idiopathic were reclassified after genetic and immunological analyses, whereas 26 (37% of nonsurgical HP) remained idiopathic. Most were treated with vitamin D (94%) and calcium (70%), and 10 received PTH. HP patients scored significantly worse than the normative population on Short Form 36 and Hospital Anxiety and Depression scale; patients with postsurgical scored worse than those with nonsurgical HP and pseudo-HP, especially on physical health. Conclusions: We found higher prevalence of nonsurgical HP in Norway than reported elsewhere. Genetic testing and autoimmunity screening of idiopathic HP identified a specific cause in 21%. Further research is necessary to unravel the causes of idiopathic HP and to improve the reduced HRQOL reported by HP patients. PMID:27186861

  6. Health-related Quality of Life in CKD Patients: Correlates and Evolution over Time

    OpenAIRE

    Mujais, Salim K.; Story, Ken; Brouillette, John; Takano, Tomoko; Soroka, Steven; Franek, Catherine; Mendelssohn, David; Finkelstein, Frederic O.

    2009-01-01

    Background and objectives: Very few large-scale studies have investigated the determinants of health-related quality of life (HRQOL) in chronic kidney disease (CKD) patients not on dialysis or the evolution of HRQOL over time.

  7. Health-related quality of life in a sample of Iranian patients on hemodialysis

    DEFF Research Database (Denmark)

    Pakpour, Amir H; Saffari, Mohsen; Yekaninejad, Mir Saeed;

    2010-01-01

    This study evaluated the health-related quality of life (HRQOL) in a sample of Iranian patients undergoing maintenance hemodialysis. The data were compared with the HRQOL for the Iranian general population....

  8. Health Related Quality of Life May Increase when Patients with a Stoma Attend Patient Education

    DEFF Research Database (Denmark)

    Danielsen, Anne Kjaergaard; Rosenberg, Jacob

    2014-01-01

    included 50 patients in the study. Health related quality of life was measured before hospital discharge, three months and six months after stoma creation. The program included educational interventions involving lay-teachers, alongside health professional teachers. RESULTS: We found a significant rise in...... in health related quality of life baseline (p = 0.045) with lower scores in the intervention group compared with the intervention group. However, there were no significant differences in the demographic variables at baseline. CONCLUSIONS: Educational activities aimed at increase in knowledge and......INTRODUCTION: Adaptation to living with a stoma is complex, and studies have shown that stoma creation has a great impact on patients' health related quality of life. The objective was to explore the effect of a structured patient education program on health related quality of life. Therefore, we...

  9. Decline in Health-Related Quality of Life 6 Months After Coronary Artery Bypass Graft Surgery

    DEFF Research Database (Denmark)

    El Baz, Noha; Pedersen, Susanne S.; van Dijk, Jitse P; Wynia, Klaske; Reijneveld, Sijmen A

    2013-01-01

    Although coronary artery bypass graft (CABG) is known to improve health-related quality of life (HRQoL), this improvement does not seem to be realized in all patients who had undergone CABG surgery....

  10. Promoting Children's Health-Related Quality of Life.

    Science.gov (United States)

    Sisk, Cara

    2016-01-01

    Pediatric health care practitioners have the ability to impact a child's HRQoL. Children's HRQoL is well documented in the literature as an important matter for children receiving health care, with research to support its significance in their lives. Children and adolescents have much to teach practitioners, and listening to their perspectives of health care experiences has a direct effect on the clinician's ability to improve their HRQoL. Pediatric practitioners focused on providing high-quality patient care must incorporate the goal to positively influence children's HRQoL. PMID:27254979

  11. Health related quality of life in Critically ill Patients A study of health related quality of life in critically ill patients admitted on the Intensive Care

    OpenAIRE

    Hofhuis, José

    2008-01-01

    textabstractHealth related quality of life (HRQOL) is a relevant outcome measure for patients admitted to the intensive care unit (ICU). Long term outcome for physical and psychological factors, functional status and social interactions are becoming more and more important both for doctors and nurses as well as for patients and their relatives (1;2). Therefore doctors and nurses want to know what a “reasonable” quality of life means to their patients. The main reason for HRQOL research descri...

  12. Health-Related Quality of Life in patients with hepatitis C in double and triple therapy

    Directory of Open Access Journals (Sweden)

    Raíssa Neves Fagundes

    2015-12-01

    Full Text Available Abstract OBJECTIVE Comparing Health-Related Quality of Life (HRQoL scores in patients with chronic hepatitis C undergoing double and triple antiviral therapy and analyzing possible factors related to HRQoL. METHOD HRQoL was assessed using the Short Form 36 and Chronic Liver Disease Questionnaire, which were applied at baseline and at weeks 4, 12 and 16 of treatment to 32 patients divided into two groups: double therapy with pegylated interferon (IFN-PEG and ribavirin, and triple therapy with PEG-IFN, ribavirin and telaprevir. RESULTS The reduction of HRQoL was greater in patients receiving triple therapy compared to those treated with two drugs, the most critical time is at 12 weeks in both groups. After removal of telaprevir, the triple therapy group significantly improved their HRQoL scores. Anxiety and depression before treatment, employment status and race are significantly related to diminished HRQoL. CONCLUSION Patients undergoing double and triple therapy have diminished HRQoL indexes, but the addition of telaprevir chooses a more significant decrease.

  13. Health related quality of life assessment in patients with hepatitis: a case of Pakistan

    OpenAIRE

    Awan, Masood Sarwar; Waqas, Muhammad; Aslam, Muhammad Amir; Abbas, Faisal

    2011-01-01

    The intention of this study is to dig out the demographic, medical, economic and psychosocial factors that affect the health related quality of life of the hepatitis B and C patient in district Sargodha. 120 patients of hepatitis B and C virus were interviewed. WHOQOL-BREF questionnaire was followed for the construction of health-related quality of life (HRQOL) instrument. Age of the patient, disease severity, use of drug, pain, depression, financial hindrance and threat of death negatively a...

  14. Status of Health related Quality of life between HBV and HCV Patients of Pakistan

    OpenAIRE

    Awan, Masood Sarwar; Waqas, Muhammad; Ali, Mumtaz; Aslam, Muhammad Amir

    2011-01-01

    The aim of the study is to explore the factors those differentiate health related quality of life (HRQOL) among hepatitis B (HBV) and hepatitis C (HCV) patients. Different public and private hospitals of Sargodha district were visited and 120 patients of hepatitis B and C were interviewed. World health related quality of life-BREF (WHOQOL-BREF) questionnaire was used to construct HRQOL instrument. Multiple regression analysis was performed to observe the collision of demographic, medica...

  15. Health-related quality of life in polycystic ovary syndrome patients: A systematic review

    OpenAIRE

    Seyed Abdolvahab Taghavi; Fatemeh Bazarganipour; Ali Montazeri; Anoshirvan Kazemnejad; Reza Chaman; Ahmad Khosravi

    2015-01-01

    Background: Increasing attention to the concept of polycystic ovary syndrome (PCOS) health-related quality of life has led to the development of tool that aims to measure this concept. Objective: The purpose of this study was to conduct a systematic review of psychometric properties of the PCOS health-related quality of life questionnaire. Materials and Methods: A search of database (Pubmed, PsychInfo, CINAHL, CENTRAL, Scopus and SID) from January1998 to December 2013 yielded 6152 refe...

  16. Health-Related Quality of Life in Primary Antibody Deficiency

    Directory of Open Access Journals (Sweden)

    Asghar Aghamohammadi

    2011-03-01

    Full Text Available Patients  with  primary  antibody  deficiencies  (PAD  are  susceptible  to  recurrent  and chronic infections and a variety of complications. This study was performed to assess quality of life (QoL of PAD patients who were under long term treatment and regular follow-up.Thirty six adults with proved diagnosis of PAD, who had received regular intravenous immunoglobulin replacement therapy, were enrolled in this study. The QoL of selected PAD patients was measured by Medical Outcomes Study 36-item Short-Form (SF-36 Health Survey questionnaire.The patients with PAD showed significantly reduced scores in physical component in comparison  with  healthy  age-sex  matched  control  subjects  (60.2±20.1  vs.  85.5±4.7, P<0.001. Mental component score was also significantly decreased in the patient's group (59.8±19.5 vs. 72.3±3.4, P=0.002. There was a reverse association between SF-36 scores and number of infections episodes (r=-0.73 P=0.003. The patients with long delay diagnosis showed significantly lower SF-36 scores (r=-0.62, P=0.003.The patients with PAD who were diagnosed timely and managed appropriately seem to have lower complications and better QoL. However, the patients with severe phenotypes and long delay in diagnosis showed lower QoL, even in medical management.

  17. Oral health-related quality of life in patients with tooth wear.

    Science.gov (United States)

    Papagianni, C E; van der Meulen, M J; Naeije, M; Lobbezoo, F

    2013-03-01

    The aim of this study was to investigate the impact of tooth wear (TW) on patients' oral health-related quality of life. A total of 198 participants were included in the study. They belonged to the following four different diagnostic categories: 51 patients with TW, 46 patients with painful temporomandibular disorders (TMD), 43 complete denture wearers and 58 healthy controls. The Dutch version of the Oral Health Impact Profile (OHIP-NL) was used to assess the patients' oral health-related quality of life. The results of the study show that patients with TW have an impaired oral health-related quality of life compared with healthy controls (P quality of life compared with painful TMD (P quality of life. This impact is comparable with that of edentulousness. PMID:23278167

  18. Health related quality of life and psychological problems in Egyptian children with simple obesity in relation to body mass index

    Directory of Open Access Journals (Sweden)

    Eman A. Abdel-Aziz

    2014-04-01

    Conclusions: Obese children and adolescents have lower health-related QOL that correlated negatively with BMI, also they are more susceptible to anxiety and depression symptoms than non obese children.

  19. Health-Related Quality of Life in Cervical Cancer Survivors: A Population-Based Survey

    International Nuclear Information System (INIS)

    Purpose: In a population-based sample of cervical cancer survivors, health-related quality of life (HRQoL) was assessed 2-10 years postdiagnosis. Methods and Materials: All patients given a diagnosis of cervical cancer in 1995-2003 in the Eindhoven region, The Netherlands, and alive after Jan 2006 were identified through the cancer registry. Generic HRQoL (36-Item Short-Form Health Survey, EQ-5D), cervical cancer-specific HRQoL (European Organization for Research and Treatment of Cancer Quality-of-Life questionnaire cervical cancer module), and anxiety (6-item State Trait Anxiety Inventory) were assessed and compared with a reference population (n = 349). Data for tumor characteristics at diagnosis and disease progression were available. Results: A total of 291 women responded (69%), with a mean age of 53 ± 13 (SD) years (range, 31-88 years). Treatment had consisted of surgery (n = 195) or a combination of therapies (n = 75); one woman had not been treated. Of all women, 85% were clinically disease free, 2% had a recurrence/metastasis, and in 13%, this was unknown. After controlling for background characteristics (age, education, job and marital status, having children, and country of birth), generic HRQoL scale scores were similar to the reference population, except for worse mental health in survivors. The most frequent symptoms were crampy pain in the abdomen or belly (17%), urinary leakage (15%), menopausal symptoms (18%), and problems with sexual activity. Compared with the 6-10-year survivors, more sexual worry and worse body image were reported by the 2-5-year survivors. Compared with surgery only, especially primary radiotherapy was associated with an increased frequency of treatment-related side effects, also after controlling for age and disease stage at diagnosis and follow-up. Conclusions: Most cervical cancer survivors were coping well, although their mental health was worse than in the reference population. Even after 2-10 years, radiotherapy was

  20. Oral health-related quality of life of children and teens with sickle cell disease

    Directory of Open Access Journals (Sweden)

    Maria Luiza da Matta Felisberto Fernandes

    2016-06-01

    Full Text Available ABSTRACT BACKGROUND: Children with sickle cell disease may have their quality of life affected by oral alterations. However, there is still little data on oral health-related quality of life in these children. The aim of this study was to investigate the influence of sickle cell disease, socioeconomic characteristics, and oral conditions on oral health-related quality of life of children and teens. METHOD: One hundred and six children and teens with sickle cell disease were compared to a similar sample of 385 healthy peers. Data were collected through oral examinations, interviews to assess quality of life (Child Perceptions Questionnaire for children aged 8-10 and 11-14 and questionnaires containing questions on socioeconomic status. RESULTS: There were no statistically significant differences in the total scores of the Child Perceptions Questionnaires or domain scores comparing sickle cell disease patients to control subjects. When sub-scales were compared, oral symptoms and functional limitations had a greater negative impact on the quality of life of adolescents with sickle cell disease (p-value <0.001 and p-value <0.01, respectively when compared to healthy controls. The only statistically significant determinants of negative impact on oral health-related quality of life in the overall sample was home overcrowding (more than two people/room in the younger children's group, and dental malocclusion among teens. CONCLUSION: There was no significant difference in the negative impact on the oral health-related quality of life between the group with sickle cell disease and the control group. Of the oral alterations, there was a significant difference in the oral health-related quality of life between adolescents with sickle cell disease and controls only in relation to malocclusion. Among the socioeconomic characteristics, only overcrowding was significantly associated with a negative impact on oral health-related quality of life.

  1. Anxiety and quality of life: clinically anxious children with and without autism spectrum disorders compared

    NARCIS (Netherlands)

    F.J.A. van Steensel; S.M. Bögels; C.D. Dirksen

    2012-01-01

    Comorbid anxiety disorders are common in children with autism spectrum disorders (ASD). However, studies comparing children with ASD to clinically anxious children are rare. This study investigated anxiety problems and health-related quality of life in children with high-functioning ASD and comorbid

  2. Associations between urban greenspace and health-related quality of life in children.

    Science.gov (United States)

    McCracken, Deborah S; Allen, Deonie A; Gow, Alan J

    2016-06-01

    With research to suggest that urban greenspace use can affect the health and wellbeing of adults, it is important to investigate this association in children. Compared with factors such as physical activity, research considering greenspace and its association with the health and wellbeing of children from urban areas is relatively rare. This study examined the health-related quality of life of 276 children residing in the city of Edinburgh in relation to quantity and use of greenspace. As much of the existing research has employed parental reports of children's health, the current study assessed health-related quality of life via self-report, measured using the Kid-KINDL questionnaire (Ravens-Sieberer & Bullinger, 1998). Spatial analysis of greenspace quantity and typology was undertaken using mapping software, ArcGIS (Esri, 2011). In regression analysis, higher greenspace use and having fewer siblings were significantly associated with better health-related quality of life. Further analysis revealed that these variables were also associated with the 'friends' sub-scale score of the Kid-KINDL. Higher greenspace use was positively associated with 'self-esteem' sub-scale scores. However, the quantity of residential greenspace was not associated with the health-related quality of life of children. This study suggests that increased use of greenspace in urban areas might have a small but positive impact on child health-related quality of life, though future longitudinal and intervention studies are required to confirm these causal assumptions. PMID:27419017

  3. Depression and health related quality of life in breast cancer patients

    International Nuclear Information System (INIS)

    Objective: To investigate the prevalence of depression in women with breast cancer and relate it to their health-related quality of life. Methods: The cross-sectional study was conducted at the Imam Khomeini Hospital in Iran between January and December 2009, and comprised 60 women with breast cancer with a mean age of 43.8+-47.12 years. In order to assess the health-related quality of life, the study used the parameters of the Iranian version of the Functional Assessment of Cancer Therapy for Breast Cancer. To identify expressive symptoms, the Beck Depression Inventory was used. General linear model regression and SPSS 14 were used to analyse the data. Results: Significant differences in the prevalence of depression between treatment types was found. The presence of depression was significantly correlated with poorer overall health-related quality of life and the four subscales of the protocol. The patients reported statistically significant effects of depression in the overall category (p= 0.001). Participants with depression were more likely to have a poorer overall health-related quality of life, the exception being the social/family well-being subscale. Conclusions: Depression affects health-related quality of life in breast cancer patients. Although further studies are necessary to confirm our findings, but our results emphasise the necessity for better mental health strategies for such patients. (author)

  4. Perceptions of Neighborhood Problems and Health-Related Quality of Life

    Science.gov (United States)

    Hill, Erin M.; Shepherd, Daniel; Welch, David; Dirks, Kim N.; McBride, David

    2012-01-01

    This article examines the association between perceptions of neighborhood problems and health-related quality of life (HRQOL) in a sample of New Zealand residents (n = 692). A modified version of the Neighborhood Problems Scale (originally developed by Steptoe and Feldman, 2001) and the World Health Organization Quality of Life (WHOQOL-BREF) were…

  5. Health-related quality of life and treatment satisfaction in Dutch patients with type 2 diabetes

    NARCIS (Netherlands)

    Redekop, WK; Rutten, GEHM; Koopmanschap, MA; Wolffenbuttel, BHR; Stolk, RP; Niessen, LW

    2002-01-01

    Objective-To estimate the health-related quality of life (HRQOL) and treatment satisfaction for patients with type 2 diabetes in the Netherlands and to examine which patient characteristics are associated with quality of life and treatment satisfaction. Research Design and Methods-For a sample of 1,

  6. Rural-Urban Analyses of Health-Related Quality of Life among People with Multiple Sclerosis

    Science.gov (United States)

    Buchanan, Robert J.; Zhu, Li; Schiffer, Randolph; Radin, Dagmar; James, Wesley

    2008-01-01

    Context: Health-related quality of life (HRQOL) is a multi-dimensional construct including aspects of life quality or function that are affected by physical health and symptoms, psychosocial factors, and psychiatric conditions. HRQOL gives a broader measure of the burden of disease than physical impairment or disability levels. Purpose: To…

  7. The relationship between media consumption and health-related anxieties after the Fukushima Daiichi nuclear disaster.

    Directory of Open Access Journals (Sweden)

    Amina Sugimoto

    Full Text Available BACKGROUND: The Fukushima Daiichi nuclear disaster caused a global panic by a release of harmful radionuclides. In a disaster setting, misusage of contemporary media sources available today can lead to disseminated incorrect information and panic. The study aims to build a scale which examines associations between media and individual anxieties, and to propose effective media usages for future disaster management. METHODS: The University of Tokyo collaborated with the Fukushima local government to conduct a radiation-health-seminar for a total of 1560 residents, at 12 different locations in Fukushima. A 13 item questionnaire collected once before and after a radiation-seminar was used on factor analysis to develop sub-scales for multiple regression models, to determine relationships between the sub-scales and media type consumed. A paired t-test was used to examine any changes in sub-scale of pre- and post-seminar scores. RESULTS: Three sub-scales were revealed and were associated with different media types: was with rumors, while concern for the future was positively associated with regional-newspapers and negatively with national-newspapers. Anxiety about social-disruption was associated with radio. The seminar had a significant effect on anxiety reduction for all the three sub-scales. CONCLUSION: Different media types were associated with various heightened concerns, and that a radiation seminar was helpful to reduce anxieties in the post-disaster setting. By tailoring post-disaster messages via specific media types, i.e., radio, it may be possible to effectively convey important information, as well as to calm fears about particular elements of post-disaster recovery and to combat rumors.

  8. The Relationship between Media Consumption and Health-Related Anxieties after the Fukushima Daiichi Nuclear Disaster

    OpenAIRE

    Amina Sugimoto; Shuhei Nomura; Masaharu Tsubokura; Tomoko Matsumura; Kaori Muto; Mikiko Sato; Stuart Gilmour

    2013-01-01

    BACKGROUND: The Fukushima Daiichi nuclear disaster caused a global panic by a release of harmful radionuclides. In a disaster setting, misusage of contemporary media sources available today can lead to disseminated incorrect information and panic. The study aims to build a scale which examines associations between media and individual anxieties, and to propose effective media usages for future disaster management. METHODS: The University of Tokyo collaborated with the Fukushima local governme...

  9. Gender Difference in Relationship between Health-Related Quality of Life and Work Status

    OpenAIRE

    Noh, Jin-Won; Kim, Jinseok; Park, Jumin; Kim, Hyun-Jung; Kwon, Young Dae

    2015-01-01

    This study investigated the association of employment status with health-related quality of life in adult Koreans, as well as the gender difference in the relationship, using a large, nationally representative sample. Using data from the Korea Health Panel survey, we examined the relationship between quality of life measured by EQ-5D and work status among Korean adults. We also tested whether and how the relationship between quality of life and work status differed by gender. Quality of life ...

  10. Oral health related quality of life in Indonesian middle-aged and elderly women

    Directory of Open Access Journals (Sweden)

    Lindawati S. Kusdhany

    2011-02-01

    Full Text Available Background: To assess oral health-related quality of life in Indonesian middle-aged and elderly women. Middle–aged women between 45-59 years old were included in this study, because this stage of life is important to prepare them  entering the old age. Prevention could be done earlier in order to achieve optimum quality of life for the elderly. The purpose of writing this paper is to inform the policy maker to develop a framework in oral health prevention.Method: Cross-sectional study was done at East Bekasi district, West Java on 236 women 45-82 years of age. Measurement of health related quality of life was performed using the Oral Health-Related Quality of Life (OHRQoL questionnaire. This questionnaire has already been translated to Indonesian language and has already been validated.Result: About 86.4% of subjects had a good oral health-related quality of life. Number of missing teeth and oral health-related quality of life have a weak correlation (correlation coeffi cient= -0.133, P= 0.041.Conclusion: Oral health-related quality of life did not depend on the number of missing teeth. These fi ndings may have implication for promoting education to middle-aged and elderly women in Indonesia about the importance of oral health.This policy frame work will be recommended to be implemented in hospitals, clinics, community care and institutional care. (Med J Indones 2011; 20:62-5Keywords: chewimg difficulties, number of missing teeth, tooth ache

  11. Health-related quality of life and happiness within an internal medicine residency training program: a longitudinal follow-up study

    Directory of Open Access Journals (Sweden)

    Abhasnee Sobhonslidsuk

    2015-02-01

    Full Text Available Purpose: While undergoing a hospital residency training program, residents often suffer anxiety and stress. This study aims to evaluate the change in health-related quality of life and happiness among internal medicine residents, and identify prognostic factors. Methods: Thirty-eight residents in the Ramathibodi Hospital internal medicine training program completed the World Health Organization Quality of Life-BREF and happiness Measures questionnaires at three time points: commencement, day 100, and the end of the second year of training. Confidence, expectations, anxiety, and general health were rated. Analyses were performed with mixed linear regression. Results: Financial problems were reported for 16 residents (42.1%. At baseline, most residents had moderate-to-very high confidence, expectations, and general health but also moderate-to-very high anxiety. The health-related quality of life score was highest in the social domain followed by the environmental, psychological, and physical domains. Their psychological, physical, social, and environmental scores significantly decreased after enrollment. Their happiness and general health scores were significantly reduced after enrollment. The training program duration was negatively associated with all domains. Residents with greater confidence had higher health-related quality of life scores in the physical, psychological, and environmental domains. Moreover, their general health was positively associated with the social and environmental domains. Conclusion: A reduction in health-related quality of life and happiness under the internal medicine residency program is reported. High confidence and good physical health may counterbalance the decline in health-related quality of life and happiness.

  12. TMD pain: the effect on health related quality of life and the influence of pain duration

    Directory of Open Access Journals (Sweden)

    Tenvergert Elisabeth M

    2010-05-01

    Full Text Available Abstract Objectives As impact of literature concerning this subject is scarce, the objectives of this study were to assess whether the Health Related Quality of Life (HRQoL is decreased in patients with painful temporomandibular disorders as compared to the HRQoL in the general population, and to evaluate to what extent pain duration affects HRQoL. Methods Data concerning physical and mental health were retrieved from patients with painful temporomandibular disorders. Assessment tools used were: the Mandibular Function Impairment Questionnaire (MFIQ, the Short-Form-36 (SF-36, the Hospital Anxiety and Depression Schedule (HADS, and the General Health Questionnaire (GHQ. In order to examine the influence of the duration of pain on HRQoL, the total sample was divided into three different subgroups. Subgroup 1 consisted of patients with complaints existing less than one year. Patients with complaints from 1 to 3 years were allocated to the second group. The 3rd subgroup included patients with complaints longer than 3 years. Results The total sample consisted of 95 patients (90 females and 5 males. On most physical and social functioning items, groups 2 and 3 scored significantly worse than the general population. On the other hand, none of the groups differed from the general population when comparing the mental items. Duration of pain was significantly correlated with SF-36 subscale physical functioning and the mandibular impairment. Conclusion Patients with TMD pain less than one year score better than compared to the population norm. With a longer duration of pain, mental health scores and role limitations due to emotional problems do not appear to be seriously affected by reduced physical health, while social functioning appears to be considerably affected.

  13. Poster Determinants for Oral-Health-Related Quality of Life among Danish adults

    DEFF Research Database (Denmark)

    Christensen, Lisa Bøge; Hede, Børge; Fiehn, Nils-Erik;

    Objectives To identify and analyze determinants for oral-health-related quality of life among adults admitted to a Danish research program on general health and lifestyle (DANHES 2007-2008) Materials and methods Study population of the present (dental) study: 4402 volunteers invited among...... participants of main study (n18065) covering 12 different Danish cities. Age 18-96 years (average 54) Structured interviews (from main study and dental study) and clinical oral examination Oral-Health-Related Quality of Life measured by a 10 item index Non-parametric statistical methods, chi-square, simple and...... multivariate logistic regression Data are not representative to the Danish population, however, associations between outcome and independent variables are considered valid. Regular dental visits and high number of natural teeth are determinants for a high level of Oral-Health-Related Quality of Life Untreated...

  14. Impact of oral health on health-related quality of life: a cross-sectional study

    OpenAIRE

    Zucoloto, Miriane Lucindo; Maroco, João; Campos, Juliana Alvares Duarte Bonini

    2016-01-01

    Background Despite the consensus regarding the existence of a relationship between “impacts on oral health” and “health-related quality of life”, this relationship, considering the latent nature of these variables, is still poorly investigated. Thus, we performed this study in order to determine the magnitude of the impacts of oral health, demographic and symptom/clinical variables on the health-related quality of life in a Brazilian sample of dental patients. Methods A total of 1,007 adult s...

  15. Assessment of health-related quality of life in patients after acute myocardial infarction

    OpenAIRE

    Rančić Nataša; Petrović Branislav; Apostolović Svetlana; Mandić Milan; Antić Ivan

    2011-01-01

    Introduction. Acute myocardial infarction has negative influence on patient’s quality of life. The objective of the paper was to assess the healthrelated quality of life in the patients one month and twelve months after acute myocardial infarction and to compare it with the healthy controls. Material and Methods. A prospective cohort study involved 160 patients aged from 30 to 79 and 240 healthy controls. The health-related quality of life was assessed with the Serbian version of these ...

  16. Validity, reliability, and responsiveness of a new shortVisual Simplified Respiratory Questionnaire (VSRQ©) for health-related quality of life assessment in chronic obstructive pulmonary disease

    OpenAIRE

    Perez, T.; Arnould, B.; Grosbois, J-M; Bosch, V; Guillemin, I; Bravo, M-L; BRUN, M.; Tonnel, A-B; ,

    2009-01-01

    The Visual Simplified Respiratory Questionnaire (VSRQ) was designed to assess health-related quality of life (HRQoL) in patients with chronic obstructive pulmonary disease (COPD). It contains eight items: dyspnea, anxiety, depressed mood, sleep, energy, daily activities, social activities and sexual life. Psychometric properties were assessed during a clinical trial that evaluated the impact of tiotropium on HRQoL of COPD patients. These included the determination of structure, internal consi...

  17. Malnutrition is associated with worse health-related quality of life in children with cancer

    NARCIS (Netherlands)

    Brinksma, Aeltsje; Sanderman, Robbert; Roodbol, Petrie F.; Sulkers, Esther; Burgerhof, Johannes G. M.; de Bont, Eveline S. J. M.; Tissing, Wim J. E.

    2015-01-01

    Malnutrition in childhood cancer patients has been associated with lower health-related quality of life (HRQOL). However, this association has never actually been tested. Therefore, we aimed to determine the association between nutritional status and HRQOL in children with cancer. In 104 children, a

  18. Pessary treatment for pelvic organ prolapse and health-related quality of life: A review

    NARCIS (Netherlands)

    B.H.C. Lamers (Babet); B.M.W. Broekman (Bart); A.L. Milani (Alfredo)

    2011-01-01

    textabstractPessaries have been used to treat women with pelvic organ prolapse (POP) since the beginning of recorded history. This review aims to assess the effect of pessary treatment on the disease-specific, health-related quality of life in women with pelvic organ prolapse. After a Medline search

  19. Health-related quality of life in children and adolescents with celiac disease

    DEFF Research Database (Denmark)

    Skjerning, Halfdan; Mahony, Ruth O; Husby, Steffen;

    2014-01-01

    Celiac disease (CD) is a chronic inflammatory disease requiring constant management with a gluten-free diet (GFD). Little is known about how CD impacts on health-related quality of life (HRQOL) in children and adolescents, and how they feel about and cope with CD and GFD. This qualitative study...

  20. Model specification in oral health-related quality of life research

    NARCIS (Netherlands)

    Kieffer, J.M.; Verrips, E.; Hoogstraten, J.

    2009-01-01

    The aim of this study was to analyze conventional wisdom regarding the construction and analysis of oral health-related quality of life (OHRQoL) questionnaires and to outline statistical complications. Most methods used for developing and analyzing questionnaires, such as factor analysis and Cronbac

  1. Dental status and oral health-related quality of life. A population-based study

    NARCIS (Netherlands)

    Visscher, C.M.; Lobbezoo, F.; Schuller, A.A.

    2014-01-01

    Summary: Oral health-related quality of life (OHRQoL) is associated with tooth wear and tooth loss. This study investigated the association between OHRQoL and dental status (in terms of natural dentition, partial or complete dentures, or edentulism). Sixteen hundred and twenty-two persons who partic

  2. Dental status and oral health-related quality of life. A population-based study

    NARCIS (Netherlands)

    Visscher, C. M.; Lobbezoo, F.; Schuller, A. A.

    2014-01-01

    Oral health-related quality of life (OHRQoL) is associated with tooth wear and tooth loss. This study investigated the association between OHRQoL and dental status (in terms of natural dentition, partial or complete dentures, or edentulism). Sixteen hundred and twenty-two persons who participated in

  3. Initial benzodiazepine use and improved health-related quality of life.

    NARCIS (Netherlands)

    van Hulten, Rolf; Teeuw, Bart; Bakker, Albert; Leufkens, Hubert G

    2005-01-01

    OBJECTIVE: The health-related quality of life (HRQOL) of initial benzodiazepine users was measured over time. Furthermore, benzodiazepine usage characteristics as determinants of change in mental and physical health status of the benzodiazepine users were examined. METHODS: In the only pharmacy of a

  4. Parenting a child with phenylketonuria or galactosemia : implications for health-related quality of life

    NARCIS (Netherlands)

    ten Hoedt, Amber E.; Maurice-Stam, Heleen; Boelen, Carolien C. A.; Rubio-Gozalbo, M. Estela; van Spronsen, Francjan J.; Wijburg, Frits A.; Bosch, Annet M.; Grootenhuis, Martha A.

    2011-01-01

    Parents of children with chronic disorders have an impaired health-related quality of life (HRQoL) compared to parents of healthy children. Remarkably, parents of children with a metabolic disorder reported an even lower HRQoL than parents of children with other chronic disorders. Possibly, the unce

  5. Intergenerational Contacts Influence Health Related Quality of Life (HRQL) and Subjective Well Being among Austrian Elderly.

    Science.gov (United States)

    Kirchengast, Sylvia; Haslinger, Beatrix

    2015-09-01

    Over the last century population ageing is a well described phenomenon all over the world. The dramatic absolute and relative increase in the population component of the elderly and the very old has influenced not only population structure but also the relationships within families, in particular between older parents and their adult children. The aim of the present study was to examine the impact of intergenerational contact frequency on health related quality of life among 62 men and 98 women ranging in age between 60 and 94 years. All participants of the study were healthy and lived independently in their private homes. Data concerning subjective well being and health related quality of life were collected by personal interviews based on structured questionnaires. Health related quality of life was tested by means of the WHOQOL-BREF. The main finding of this study is that the frequency of intergenerational contacts has a significant impact on health related quality of life. Contact frequency with grandchildren per month correlated significantly (pquality of life increased significantly (pquality of life during old age. PMID:26898049

  6. Health-related quality of life in the elderly three years after percutaneous coronary intervention

    NARCIS (Netherlands)

    A. Panasewicz (Anna); S.S. Pedersen (Susanne); S.J.G. Veenhuis (Stefanie); R.M. Oemrawsingh (Rohit); W.J. van der Giessen (Wim); R.J.M. van Geuns (Robert Jan); E.S. Regar (Eveline); P.P.T. de Jaegere (Peter); P.W.J.C. Serruys (Patrick); R.T. van Domburg (Ron)

    2013-01-01

    textabstractAims: Long-term health-related quality of life (HRQOL) in the elderly after percutaneous coronary intervention (PCI) is unknown. We 1) compared HRQOL of elderly (=70 years) with younger patients (<70 years) at 6, 12, 36 months post-PCI, and 2) examined whether predictors of impaired HRQO

  7. Translation of questionnaires measuring health related quality of life is not standardized

    DEFF Research Database (Denmark)

    Danielsen, Anne Kjaergaard; Pommergaard, Hans-Christian; Burcharth, Jakob;

    2015-01-01

    reporting the methodological process when translating questionnaires on health related quality of life for different diseases. RESULTS: We retrieved 187 studies and out of theses we included 52 studies. The psychometric properties of the translated versions were validated using different tests. The focus...

  8. A Longitudinal Analysis of Rural and Urban Veterans' Health-Related Quality of Life

    Science.gov (United States)

    Wallace, Amy E.; Lee, Richard; MacKenzie, Todd A.; West, Alan N.; Wright, Steven; Booth, Brenda M.; Hawthorne, Kara; Weeks, William B.

    2010-01-01

    Context: Cross-sectional studies have identified rural-urban disparities in veterans' health-related quality-of-life (HRQOL) scores. Purpose: To determine whether longitudinal analyses confirmed that these disparities in veterans' HRQOL scores persisted. Methods: We obtained data from the SF-12 portion of the veterans health administration's…

  9. Health-related quality of life, employment and disability in patients with Sjogren's syndrome

    NARCIS (Netherlands)

    Meijer, Jiska M.; Meiners', Petra M.; Slater, James J. R. Huddleston; Spijkervet, Fred K. L.; Kallenberg, Cees G. M.; Vissink, Arjan; Bootsma, Hendrika

    2009-01-01

    Objective. To compare health-related quality of life (HR-QOL), employment and disability of primary and secondary SS (pSS and sSS, respectively) patients with the general Dutch population. Methods. HR-QOL, employment and disability were assessed in SS patients regularly attending the University Medi

  10. EAACI Food Allergy and Anaphylaxis Guidelines : Food allergy health-related quality of life measures

    NARCIS (Netherlands)

    Muraro, A.; Dubois, Anthony; DunnGalvin, A.; Hourihane, J. O'B.; de Jong, N. W.; Meyer, R.; Panesar, S. S.; Roberts, G.; Salvilla, S.; Sheikh, A.; Worth, A.; Flokstra-de Blok, B. M. J.

    2014-01-01

    Instruments have been developed and validated for the measurement of health-related quality of life in patients with food allergy. This guideline has been prepared by the European Academy of Allergy and Clinical Immunology's (EAACI) Guidelines for Food Allergy and Anaphylaxis Group. It draws on a sy

  11. Health-Related Quality of Life and Health-Promoting Behaviors in Black Men

    Science.gov (United States)

    Calvert, Wilma J.; Isaac,, E. Paulette; Johnson, Sharon

    2012-01-01

    This study examined the health-related quality of life and health-promoting behaviors in a convenience sample of low-income black men. Almost three-fourths reported their overall health as good or better. However, the mean number of recent (that is, past 30 days) mentally unhealthy days was 13.12, and more than half reported frequent (greater than…

  12. Dental status and oral health-related quality of life: a population-based study

    NARCIS (Netherlands)

    C.M. Visscher; F. Lobbezoo; A.A. Schuller

    2014-01-01

    Oral health-related quality of life (OHRQoL) is associated with tooth wear and tooth loss. This study investigated the association between OHRQoL and dental status (in terms of natural dentition, partial or complete dentures, or edentulism). Sixteen hundred and twenty-two persons who participated in

  13. Health-related quality of life in asthma studies. Can we combine data from different countries?

    NARCIS (Netherlands)

    Stahl, E; Postma, DS; Juniper, EF; Svensson, K; Mear, [No Value; Lofdahl, CG

    2003-01-01

    The aim was to compare health-related quality of life (HRQL) in patients with asthma from 4 countries, and to investigate the correlations between HRQL and clinical indices. 341 patients; 140 (Sweden), 54 (Norway), 65 (the Netherlands) and 82 (Greece) were treated with formoterol fumarate 4.5 mug or

  14. Motor performance, exercise tolerance, and health-related quality of life in children on dialysis

    NARCIS (Netherlands)

    Eijsermans, RM; Creemers, DG; Helders, PJ; Schroder, CH

    2004-01-01

    In contrast to the adult population, little is known regarding health-related quality of life and exercise tolerance in children with end-stage renal disease (ESRD) undergoing chronic intermittent hemodialysis. We designed a pilot study to investigate whether research into this area is indicated. Th

  15. Adult Day Health Center Participation and Health-Related Quality of Life

    Science.gov (United States)

    Schmitt, Eva M.; Sands, Laura P.; Weiss, Sara; Dowling, Glenna; Covinsky, Kenneth

    2010-01-01

    Purpose: The purpose of this study was to assess the association between Adult Day Health Center (ADHC) participation and health-related quality of life. Design and Methods: Case-controlled prospective study utilizing the Medical Outcomes Survey Form 36 (SF-36) to compare newly enrolled participants from 16 ADHC programs with comparable…

  16. Health related quality of life, cognitive functioning and behaviour problems in children

    NARCIS (Netherlands)

    C.M.J. Vrijmoet-Wiersma; V.M. Kooloos; H.M. Koopman; A.M. Kolk; I. van der Laan; M.A. Grootenhuis; R.M. Egeler

    2009-01-01

    Background: This study was designed to evaluate generic and disease-specific health-related quality of life (HRQoL), cognitive functioning and behaviour problems of children with Langerhans Cell Histiocytosis (LCH). Furthermore, we investigated which medical determinants and social demographic facto

  17. Dental implants and improvement of oral health-related quality of life

    Czech Academy of Sciences Publication Activity Database

    Kříž, P.; Seydlová, M.; Dostálová, T.; Valenta, Zdeněk; Chleborád, K.; Zvárová, Jana; Feberová, J.; Hippmann, R.

    2012-01-01

    Roč. 40, Suppl. 1 (2012), s. 65-70. ISSN 0301-5661 R&D Projects: GA MŠk(CZ) 1M06014 Institutional research plan: CEZ:AV0Z10300504 Keywords : dental implant * oral health-related quality of life Subject RIV: FF - HEENT, Dentistry Impact factor: 1.797, year: 2012

  18. Religiousness and health-related quality of life of older adults

    Directory of Open Access Journals (Sweden)

    Gina Andrade Abdala

    2015-01-01

    Full Text Available OBJECTIVE To examine whether religiousness mediates the relationship between sociodemographic factors, multimorbidity and health-related quality of life of older adults.METHODS This population-based cross-sectional study is part of the Survey on Health, Well-Being, and Aging (SABE. The sample was composed by 911 older adults from Sao Paulo, SP, Southeastern Brazil. Structural equation modeling was performed to assess the mediator effect of religiousness on the relationship between selected variables and health-related quality of life of older adults, with models for men and women. The independent variables were: age, education, family functioning and multimorbidity. The outcome variable was health-related quality of life of older adults, measured by SF-12 (physical and mental components. The mediator variables were organizational, non-organizational and intrinsic religiousness. Cronbach’s alpha values were: physical component = 0.85; mental component = 0.80; intrinsic religiousness = 0.89 and family APGAR (Adaptability, Partnership, Growth, Affection, and Resolve = 0.91.RESULTS Higher levels of organizational and intrinsic religiousness were associated with better physical and mental components. Higher education, better family functioning and fewer diseases contributed directly to improved performance in physical and mental components, regardless of religiousness. For women, organizational religiousness mediated the relationship between age and physical (β = 2.401, p CONCLUSIONS Organizational and intrinsic religiousness had a beneficial effect on the relationship between age, education and health-related quality of life of these older adults.

  19. Health-related quality of life research and the capability approach of Amartya Sen

    NARCIS (Netherlands)

    Verkerk, M.A.; Busschbach, J.J.V.; Karssing, E.D.

    2001-01-01

    Standardised health-related quality of life questionnaires play an increasing role as measures of outcome in the evaluation of health care interventions. However, problems can arise when the selected functions or dimensions of such standardised measures are not in line with the intervention that is

  20. Differential item functioning (DIF) analyses of health-related quality of life instruments using logistic regression

    DEFF Research Database (Denmark)

    Scott, Neil W.; Fayers, Peter M.; Aaronson, Neil K.;

    2010-01-01

    Differential item functioning (DIF) methods can be used to determine whether different subgroups respond differently to particular items within a health-related quality of life (HRQoL) subscale, after allowing for overall subgroup differences in that scale. This article reviews issues that arise...

  1. Health-related quality of life in multiple sclerosis patients with bladder, bowel and sexual dysfunction

    NARCIS (Netherlands)

    Vitkova, Marianna; Rosenberger, Jaroslav; Krokavcova, Martina; Szilasiova, Jarmila; Gdovinova, Zuzana; Groothoff, Johan W.; van Dijk, Jitse P.

    2014-01-01

    Purpose: Bladder, bowel and sexual dysfunction are often overlooked symptoms in patients with multiple sclerosis (MS) and can be associated with lower health-related quality of life (HRQoL). The aim is to explore the association of bladder, bowel and sexual dysfunction with HRQoL in MS patients stra

  2. Health-related quality of life of 256 recipients after liver transplantation

    Institute of Scientific and Technical Information of China (English)

    Pei-Xian Chen; Lu-Nan Yan; Wen-Tao Wang

    2012-01-01

    AIM:To investigate health-related quality of life (HRQoL)and psychological outcomes in 256 adults who had undergone liver transplantation (LT).METHODS:A stratified random sampling method was used in this follow-up multicenter study to select a representative sample of recipients undergoing either living donor liver transplantation (LDLT) or deceased donor liver transplantation (DDLT).HRQoL was measured by using the Chinese version of Medical Outcome Study Short Form-36 (SF-36),and psychological outcomes by using the beck anxiety inventory (BAI)and the self-rating depression scale (SDS).Clinical and demographic data were collected from the records of the Chinese Liver Transplant Registry and via questionnaires.RESULTS:A total of 256 patients were sampled,including 66 (25.8%) receiving LDLT and 190 (74.2%)undergoing DDLT; 15 (5.9%) recipients had anxiety and four (1.6%) developed severe depression after the operation.Compared with LDLT recipients,DDLT patients had higher scores in general health (60.33± 16.97 vs 66.86 ± 18.42,P =0.012),role-physical (63.64 ± 42.55 vs 74.47 ± 36.46,P =0.048),roleemotional (61.11 ± 44.37 vs 78.95 ± 34.31,P =0.001),social functioning (78.60 ± 22.76 vs 88.16 ± 21.85,P =0.003),vitality (70.30 ± 15.76 vs 75.95 ± 16.40,P =0.016),mental health (65.88 ± 12.94 vs 71.85 ±15.45,P =0.005),physical component summary scale (PCS,60.07 ± 7.36 vs 62.58 ± 6.88,P =0.013) and mental component summary scale (MCS,52.65 ± 7.66vs 55.95 ± 10.14,P =0.016).Recipients > 45 years old at the time of transplant scored higher in vitality (77.33 ± 15.64 vs 72.52 ± 16.66,P =0.020),mental health (73.64 ± 15.06 vs 68.00 ± 14.65,P =0.003)and MCS (56.61 ± 10.00 vs 54.05 ± 9.30,P =0.037)than those aged ≤ 45 years.MCS was poorer in recipients with than in those without complications (52.92± 12.21 vs 56.06 ± 8.16,P =0.017).Regarding MCS (55.10 ± 9.66 vs 50.0 ± 10.0,P < 0.05) and PCS (61.93± 7.08 vs 50.0 ± 10.0,P < 0.05),recipients

  3. Validation of the nausea and vomiting of pregnancy specific health related quality of life questionnaire

    OpenAIRE

    Lacasse Anaïs; Bérard Anick

    2008-01-01

    Abstract Background The only existing NVP-specific quality of life (QOL) questionnaire is the "Health-Related Quality of Life for Nausea and Vomiting during Pregnancy" (NVPQOL). However, the reliability and validity of the NVPQOL have never been established. In order to justify its usage, the internal consistency and criterion validity of the NVPQOL questionnaire must be ascertained. Methods A prospective observational study including pregnant women attending CHU Sainte-Justine or René-Laenne...

  4. Impaired Health-related Quality of Life in Caregivers of Youth Seeking Obesity Treatment

    OpenAIRE

    Modi, Avani C.; Guilfoyle, Shanna M.; Zeller, Meg H.

    2008-01-01

    Objective To document and identify predictors of caregiver health-related quality of life (HRQOL) in a sample of youth seeking obesity treatment and examine whether it moderates the relation between parent proxy and youth self-report HRQOL. Methods Youth (5–18 years) and their caregivers (N = 120) presenting to a pediatric medical weight management program completed the Pediatric Quality of Life Inventory™ and caregivers completed the Short-Form 36. Results Caregivers were predominantly overw...

  5. Health-Related Quality of Life In Two Itinerant Samples: Carnival and Migrant Farm Worker Children

    OpenAIRE

    Kilanowski, Jill F.

    2009-01-01

    The document Healthy People 2010 sets a national health care agenda that includes reducing health disparities and improving quality of life. This study evaluated health-related quality of life (HRQOL) in children aged 2 to 12 years being raised in two itinerant populations: traveling carnival children (n = 33) and migrant farm worker children (n = 48), and compared their outcomes to each other and to findings in published literature. The study sample utilized cluster sampling from outdoor amu...

  6. Socio-economic differences in the health-related quality of life impact of cardiovascular conditions

    OpenAIRE

    Stafford, M.; Soljak, M.; Pledge, V.; Mindell, J.

    2011-01-01

    Background: Those responsible for planning and commissioning health services require a method of assessing the benefits and costs of interventions. Quality-adjusted life years, based on health-related quality of life (HRQoL) estimates, can be used as part of this commissioning process. The purpose of this study was to generate nationally representative HRQoL estimates for cardiovascular disease (heart attack, angina and stroke) and predisposing conditions (diabetes, hypertension and obesity) ...

  7. Optimism as a predictor of health-related quality of life in psoriatics

    OpenAIRE

    Miniszewska, Joanna; Chodkiewicz, Jan; Ograczyk, Alicja; Zalewska-Janowska, Anna

    2013-01-01

    Introduction Psoriasis is a chronic and relapsing disease which significantly affects the quality of life and social functioning of the affected people. It is one of the so-called psychodermatological diseases, which means that there exists a psychological component in the image of the disease. Aim To examine the relationship between health-related quality of life (HRQoL) in psoriatics and selected demographic, medical and psychological (dispositional optimism) variables and to determine the ...

  8. Health related quality of life among Iraqi immigrants settled in Malaysia

    OpenAIRE

    Daher Thaaer M; Ibrahim Hisham S; Daher Aqil M; Anbori Ali

    2011-01-01

    Abstract Background Migrants everywhere face several demands for health and maintaining good health and quality of life could be challenging. Iraqis are the second largest refugee group that has sought refuge in the recent years, yet little is known about their health related quality of life (HRQOL). The study aims at assessing the HRQOL among Iraqis living in Malaysia. Methods A self-administered Arabic version of Sf-36 questionnaire was distributed among 300 Iraqi migrants in Malaysia. The ...

  9. Health-related quality of life in sacroiliac syndrome: A comparison to lumbosacral radiculopathy

    OpenAIRE

    Cheng, Marc B; Ferrante, F Michael

    2006-01-01

    Background and objectives: This study attempts to assess the intensity and quality of pain and health-related quality of life in patients with sacroiliac syndrome and to compare those constructs to patients with lumbar radiculopathy. Methods: A retrospective review of patient records with the diagnosis of sacroiliac syndrome or lumbar radiculopathy was performed. Patients with sacroiliac syndrome were age and gender matched to patients with lumbar radiculopathy. Data from the McGill Pain Ques...

  10. Relationship of optimism-pessimism and health-related quality of life in breast cancer survivors.

    Science.gov (United States)

    Petersen, Larra R; Clark, Matthew M; Novotny, Paul; Kung, Simon; Sloan, Jeff A; Patten, Christi A; Vickers, Kristin S; Rummans, Teresa A; Frost, Marlene H; Colligan, Robert C

    2008-01-01

    Few studies have investigated the influence of optimism-pessimism in breast cancer survivors. This study used a retrospective design with 268 adult women who completed the Minnesota Multiphasic Personality Inventory (MMPI) as part of their medical care approximately 10 years prior to their breast cancer diagnosis and Medical Outcome Study Short-Form General Health Survey (SF-36 or SF-12), on average, 8 years after diagnosis. MMPI pessimism scores were divided into quartiles, and t tests were used to determine differences between those highest and lowest in pessimism on health-related quality-of-life (QOL) measures, demographics, and disease status. The mean age at diagnosis of breast cancer was 63 years, and 74% had early-stage breast cancer. Patients age 65 years and older were significantly lower on physical health related QOL scales. There were no significant differences in health-related QOL scores by stage of disease. Patients with a pessimistic explanatory style were significantly lower on all of the health-related QOL scores, compared to those with a nonpessimistic style. Breast cancer survivors who exhibit a pessimistic explanatory style report lower health-related QOL for years after receiving a cancer diagnosis, compared to nonpessimistic women. PMID:19042270

  11. Issues for researchers to consider when using health-related quality of life outcomes in cancer research.

    Science.gov (United States)

    McCabe, C; Cronin, P

    2011-09-01

    Maintaining quality of life for patients with cancer is a key factor when developing services related to diagnosis, treatment, recovery and/or terminal care. This paper questions whether health-related quality of life (HRQoL) is an appropriate measure of quality of life given that it does not assess factors reported by patients as being most influential, e.g. contact with family and social/cultural interaction. Ambiguity related to the definition and understanding of anxiety, depression and distress as outcomes commonly used by clinicians and researchers when measuring HRQoL in cancer research is also addressed by this paper. The findings of many cancer studies are interpreted and presented on very broad and poorly defined concepts thus preventing the development of a coherent and true understanding of how these outcomes influence quality of life for cancer patients. The authors of this paper conclude that the documentation and clear explanation of the concepts underpinning the choice of instrument and study design is essential but also the inclusion of outcomes related to social support and interaction would provide a more accurate account of quality of life issues in cancer research. PMID:21029221

  12. Relationship of Parity and Health Related Quality of Life among women

    Directory of Open Access Journals (Sweden)

    S. Singh

    2015-04-01

    Full Text Available Background: Women have unique health issues and these are paid increased concern in recent time. Pregnancy is an important event for reproductive-age women, where in nine months body undergoes many physiological changes. Even though these changes are normal, women experience a substantial decline in health status during and after pregnancy. Quality of life (QOL is used to define overall wellbeing of person and it includes physical, psychological, social, economic and political perspectives. In recent times medical decision making research have focused increasingly on health related quality of life (HRQOL as an important variable as this can benefit patients, clinicians, researchers and health maintenance organizations. Aim –The study was done to determine the impact of parity status among women on their health related quality of life. Method – Total 60 female subjects meeting the inclusion criteria constituted population of the study. The health related quality of life was assessed using SF-36v2 questionnaire. Results –The analysis of coefficient of correlation for SF-36v2 components indicated significant negative correlation between parity status and seven components of SF-36v2: PF (r = -0.49, RP (r = -0.39, BP (r = -0.51, GH (r = -0.42, VT (r = -0.43, RE (r = -0.29 and MH (r = -0.41 at p≤0.05. Whereas, a non-significant correlation was observed between parity and one of the component SF (Social Function of the questionnaire, SF (r = -0.14 at p≤0.05. Scoring of SF-36v2 questionnaire also provided total component scores i.e. PCS (Physical Component Score and MCS (Mental Component Score. Coefficient of correlation analysis for PCS (r = -0.50 and MCS (r = -0.30 showed significant negative correlation with parity status at p≤0.05. Conclusion – Females with higher parity status tend to have poorer health related quality of life.

  13. The independent contribution of executive functions to health related quality of life in older women

    Directory of Open Access Journals (Sweden)

    Marra Carlo A

    2010-04-01

    Full Text Available Abstract Background Cognition is a multidimensional construct and to our knowledge, no previous studies have examined the independent contribution of specific domains of cognition to health related quality of life. To determine whether executive functions are independently associated with health related quality of life assessed using Quality Adjusted Life Years (QALYs calculated from the EuroQol EQ-5D (EQ-5D in older women after adjusting for known covariates, including global cognition. Therefore, we conducted a secondary analysis of community-dwelling older women aged 65-75 years who participated in a 12-month randomized controlled trial of resistance training. We assessed global cognition using the Mini-Mental State Examination (MMSE and executive functions using the: 1 Stroop Test; 2 Trail Making Test (Part B and 3 Digits Verbal Span Backwards Test. We calculated QALYs from the EQ-5D administered at baseline, 6 months and 12 months. Results Our multivariate linear regression model demonstrated the specific executive processes of set shifting and working memory, as measured by Trail Making Test (Part B and Digits Verbal Span Backward Test (p Conclusions Our study highlights the specific executive processes of set shifting and working memory were independently associated with QALYs -- a measure of health related quality of life. Given that executive functions explain variability in QALYs, clinicians may need to consider assessing executive functions when measuring health related quality of life. Further, the EQ-5D may be used to track changes in health status over time and serve as a screening tool for clinicians. Trial Registration ClinicalTrials.gov Identifier: NCT00426881.

  14. Health-related Quality of Life in Women with Polycystic Ovary Syndrome

    Directory of Open Access Journals (Sweden)

    Belén Carazo Hernández

    2014-04-01

    Full Text Available Polycystic ovary syndrome is the most frequent endocrine and metabolic disorder in women of reproductive age. Its characteristic signs and symptoms are menstrual irregularities, amenorrhea, acne, hirsutism, obesity and infertility. Polycystic ovary syndrome has major effects on long-term health, which can lead to psychological morbidity and decreased quality of life. This paper reviews the current literature on polycystic ovary syndrome and health-related quality of life; in addition, it assesses how some clinical manifestations of polycystic ovary syndrome affect the quality of life of women who suffer this disorder.

  15. Health-Related Quality of Life of Rural Clients Seeking Telepsychology Services

    Directory of Open Access Journals (Sweden)

    Kevin R. Tarlow

    2014-01-01

    Full Text Available Sixty million US residents live in rural areas, but health policies and interventions developed from an urban mindset often fail to address the significant barriers to health experienced by these local communities. Telepsychology, or psychological services delivered by distance via technology, is an emerging treatment modality with special implications for underserved rural areas. This study found that a sample of rural residents seeking telepsychology services (n=94 had low health-related quality of life (HRQOL, often due to cooccurring physical and mental health diagnoses including high rates of depression. However, a brief telepsychology treatment delivered to rural clients (n=40 was associated with an improvement in mental health-related quality of life (d = 0.70,  P<.001. These results indicate that despite the complex health needs of these underserved communities, telepsychology interventions may help offset the disparities in health service access in rural areas.

  16. Physical activity, health-related quality of life and depression during pregnancy

    OpenAIRE

    Tendais, Iva; Figueiredo, Bárbara; Mota, Jorge; Conde, Ana

    2011-01-01

    This study examines physical activity patterns among women, from pre-pregnancy to the second trimester of pregnancy, and the relationship between physical activity status based on physical activity guidelines and health-related quality of life (HRQoL) and depression over pregnancy. 56 healthy pregnant women self reported physical activity, HRQoL and depression at 10-15 and 19-24 weeks of pregnancy and physical activity before pregnancy. Whereas vigorous leisure physical activity decreased aft...

  17. Health-related quality-of-life instruments for Alzheimer's disease and mixed dementia

    OpenAIRE

    Perales Puchalt, Jaime, 1985-; Cosco, Theodore D; Stephan, Blossom C. M.; Haro, Josep Maria; Brayne, Carol

    2014-01-01

    BACKGROUND: Over the last 20 years, a number of instruments developed for the assessment of health-related quality of life (HRQL) in dementia have been introduced. The aim of this review is to synthesize evidence from published reviews on HRQL measures in dementia and any new literature in order to identify dementia specific HRQL instruments, the domains they measure, and their operationalization. METHODS: An electronic search of PsycINFO and PubMed was conducted, from inception to December 2...

  18. Health-related quality of life in patients with dual diagnosis: clinical correlates

    OpenAIRE

    Benaiges Irina; Prat Gemma; Adan Ana

    2012-01-01

    Abstract Background Although the studies published so far have found an affectation in the Health Related Quality of Life (HRQOL) in both psychiatric and substance use dependence disorders, very few studies have applied HRQOL as an assessment measure in patients suffering both comorbid conditions, or Dual Diagnosis. The aim of the current study was to assess HRQOL in a group of patients with Dual Diagnosis compared to two other non-comorbid groups and to determine what clinical factors are re...

  19. Health-related quality of life among colorectal cancer patients in Malaysia: a study protocol

    OpenAIRE

    Magaji Bello; Moy Foong; Roslani April; Sagap Ismail; Zakaria Jasiah; Blazeby Jane M; Law Chee

    2012-01-01

    Abstract Background Colorectal cancer is a major public health problem in Malaysia. However, it is also one of the most treatable cancers, resulting in significant numbers of survivors. Therefore, the impact of surviving treatment for colorectal cancer on health related quality of life is important for the patients, clinicians and policy makers, and may differ in different cultures and populations. The aim of this study was to validate the Malaysian versions of the European Organization for R...

  20. HEALTH RELATED QUALITY OF LIFE (HRQoL) IN EATING DISORDERS

    OpenAIRE

    RAČANSKÁ, Lucie

    2009-01-01

    The dissertation {\\clq}qHealth Related Quality of Life (HRQoL) in Eating Disorders`` is divided into theoretical and practical part. In the theoretical part is analyzes the problems with eating disorders. It is especially focused on its two basics forms, anorexia nervosa and bulimia which are illnesses occasioned by hypothrepsia. The next part drala with history, symptoms, cause, medication, process, prognosis and complications resulting from these disorders, including the main diagnostic cri...

  1. Oral health-related quality of life of edentulous patients after complete dentures relining

    OpenAIRE

    Krunić Nebojša; Kostić Milena; Petrović Milica; Igić Marko

    2015-01-01

    Background/Aim. Tooth loss affects oral health-related life quality. More than a third of edentulous patients are not fully satisfied with their complete dentures and mainly complain of insufficient stability, retention, and pain during mastication. Solving the problem may include relining by materials that are based on silicone or acrylic. The aim of this study was to determine the level of patients’ satisfaction before and after relining upper dentures wi...

  2. Health related quality of life and mental distress after PCI: restoring a state of equilibrium

    OpenAIRE

    Sipötz, Johann; Friedrich, Oliver; Höfer, Stefan; Benzer, Werner; Chatsakos, Thomas; Gaul, Georg

    2013-01-01

    Background Patient self reported measures for Health Related Quality of Life (HRQOL) and mental distress are frequently used to evaluate outcome of therapeutic strategies in cardiac patients. Our study aims to describe changes in HRQOL and mental distress after percutaneous coronary intervention (PCI) focusing on temporal pattern of change and interdependences between both outcome measures. Method 163 PCI patients recruited at 7 cardiovascular care units in Austria answered MacNew Health Rela...

  3. Centella asiatica Improves Physical Performance and Health-Related Quality of Life in Healthy Elderly Volunteer

    OpenAIRE

    Lugkana Mato; Jintanaporn Wattanathorn; Supaporn Muchimapura; Terdthai Tongun; Nawanant Piyawatkul; Kwanchanok Yimtae; Panida Thanawirattananit; Bungorn Sripanidkulchai

    2011-01-01

    Recently, oxidative stress has been reported to contribute an important role in the decline of physical function as age advances. Numerous antioxidants can improve both physical and psychological performances resulting in the increase of health-related quality of life (HQOL). Therefore, we hypothesized that Centella asiatica, a medicinal plant reputed for nerve tonic, strength improvement and antioxidant activity, could improve the physical performance and HQOL especially in the physical sati...

  4. Oral Health-Related Quality of Life in institutionalized elderly in Barcelona (Spain)

    OpenAIRE

    Cornejo, Marco; Pérez de, Gloria; Lima, Kenio-Costa de; Casals Peidró, Elías; Borrell, Carme

    2013-01-01

    Objective: The objective of this study is to describe the oral health status and the factors associated with oral health-related quality of life (OHRQoL) in people aged 65 and older institutionalized in Barcelona in 2009. Study Design: Cross sectional study in 194 elderly. The dependent variable was poor OHRQoL, according to the Geriatric Oral Health Assessment Index (GOHAI). The independent variables were socio-demographic data, last dental visit, subjective and objective oral health status....

  5. Parenting a child with phenylketonuria or galactosemia: implications for health-related quality of life

    OpenAIRE

    Hoedt, ten, A.E.; Maurice-Stam, H.; Boelen, C.C.A.; Rubio-Gozalbo, M.E.; Spronsen, van, M.; Wijburg, F A; Bosch, A. M.; Grootenhuis, M.A.

    2011-01-01

    Parents of children with chronic disorders have an impaired health-related quality of life (HRQoL) compared to parents of healthy children. Remarkably, parents of children with a metabolic disorder reported an even lower HRQoL than parents of children with other chronic disorders. Possibly, the uncertainty about the course of the disease and the limited life expectancy in many metabolic disorders are important factors in the low parental HRQoL. Therefore, we performed a cross-sectional study ...

  6. Domestic Violence during Pregnancy and Women’s Health-Related Quality of Life

    OpenAIRE

    Gharacheh, Maryam; Azadi, Shahdokht; Mohammadi, Nooredin; Montazeri, Simin; Khalajinia, Zohre

    2015-01-01

    Domestic violence during pregnancy is a major health problem with significant psychological and physical impairments for pregnant women. To assess the relationship between domestic violence during pregnancy and women’s health-related quality of life (HRQoL), a cross-sectional study was conducted on 341 postnatal women who referred to urban health care centers in Gachsaran, Islamic Republic of Iran. Domestic violence was assessed using a questionnaire modified from the Abuse Assessment Screen ...

  7. Predictors of future health-related quality of life in survivors of adolescent cancer

    OpenAIRE

    Nolan, Vikki G.; Krull, Kevin R.; Gurney, James G.; Leisenring, Wendy; Robison, Leslie L.; Ness, Kirsten K.

    2014-01-01

    The purpose of this study was to identify characteristics associated with health-related quality of life (HRQOL) among long-term survivors of adolescent cancer enrolled in the Childhood Cancer Survivor Study. Thirty percent of survivors reported poor physical and/or mental HRQOL. Race/ethnicity, education, and head/neck disfigurement were significantly associated with poor mental HRQOL, while sex, age, household income, obesity, alkylating agents, pelvic radiation, head/neck or limb disfigure...

  8. Health-related quality of life questionnaires in lung cancer trials: A systematic literature review

    OpenAIRE

    Damm, Kathrin; Roeske, Nicole; Jacob, Christian

    2013-01-01

    Background: Lung cancer is one of the leading causes of cancer deaths. Treatment goals are the relief of symptoms and the increase of overall survival. With the rising number of treatment alternatives, the need for comparable assessments of health-related quality of life (HRQoL) parameters grows. The aim of this paper was to identify and describe measurement instruments applied in lung cancer patients under drug therapy. Methods: We conducted a systematic literature review at the beginning of...

  9. Does dental indifference influence the oral health-related quality of life of prisoners?

    OpenAIRE

    Marshman, Z.; Baker, S. R.; Robinson, P G

    2014-01-01

    Objectives Prisoners have worse oral health and greater unmet dental treatment needs than the general population. However, little is known about the impact of the mouth, or attitudes such as dental indifference and consequent patterns of dental service use in this disadvantaged group. The aim was to determine whether dental indifference was associated with the oral health-related quality of life (OHQoL) of prisoners using Andersen's behavioural model of service utilization as the theor...

  10. Stress on health-related quality of life in older adults: the protective nature of mindfulness

    OpenAIRE

    de Frias, Cindy M.; Whyne, Erum

    2014-01-01

    Objectives: The current study examined whether the link between stress and health-related quality of life was buffered by protective factors, namely mindfulness, in a sample of middle-aged and older adults. Methods: In this cross-sectional study, 134 healthy, community-dwelling adults (ages 50–85 years) were recruited from Dallas, TX. The participants were screened for depressive symptoms and severity (using the Patient Health Questionnaire [PHQ-9]). All participants completed measures of sel...

  11. Health-related quality of life among older adults with arthritis

    OpenAIRE

    Gold Carol H; Ahern Frank M; Dominick Kelli L; Heller Debra A

    2004-01-01

    Abstract Background Health-related quality of life (HRQOL) is a key outcome in arthritis, but few population-based studies have examined the relationship of specific arthritic conditions, such as osteoarthritis (OA) and rheumatoid arthritis (RA) with HRQOL. Methods Older adults in Pennsylvania completed a mail version of the Centers for Disease Control and Prevention (CDC) HRQOL modules. Medicare data were used to identify subjects with OA, RA, and no arthritis diagnosis. We compared HRQOL re...

  12. Associations between urban greenspace and health-related quality of life in children

    OpenAIRE

    McCracken, Deborah S.; Allen, Deonie A.; Gow, Alan J.

    2016-01-01

    With research to suggest that urban greenspace use can affect the health and wellbeing of adults, it is important to investigate this association in children. Compared with factors such as physical activity, research considering greenspace and its association with the health and wellbeing of children from urban areas is relatively rare. This study examined the health-related quality of life of 276 children residing in the city of Edinburgh in relation to quantity and use of greenspace. As muc...

  13. Differential item functioning (DIF) analyses of health-related quality of life instruments using logistic regression

    DEFF Research Database (Denmark)

    Scott, Neil W; Fayers, Peter M; Aaronson, Neil K;

    2010-01-01

    Differential item functioning (DIF) methods can be used to determine whether different subgroups respond differently to particular items within a health-related quality of life (HRQoL) subscale, after allowing for overall subgroup differences in that scale. This article reviews issues that arise...... when testing for DIF in HRQoL instruments. We focus on logistic regression methods, which are often used because of their efficiency, simplicity and ease of application....

  14. Health-related quality of life of Canadian children and youth prenatally exposed to alcohol

    OpenAIRE

    Ungar Wendy J; Stevens Bonnie; Stade Brenda C; Beyene Joseph; Koren Gideon

    2006-01-01

    Abstract Background In Canada, the incidence of Fetal Alcohol Spectrum Disorder (FASD) has been estimated to be 1 in 100 live births. Caused by prenatal exposure to alcohol, FASD is the leading cause of neuro-developmental disabilities among Canadian children, and youth. Objective: To measure the health-related quality of life (HRQL) of Canadian children and youth diagnosed with FASD. Methods A prospective cross-sectional study design was used. One-hundred and twenty-six (126) children and yo...

  15. Health-Related Quality of Life after Cystectomy and Urinary Diversion for Bladder Cancer

    OpenAIRE

    Cheryl Shih; Porter, Michael P

    2011-01-01

    With multiple options for urinary diversion after radical cystectomy for bladder cancer that have comparable cancer control and complication rates, health-related quality of life (HRQOL) has become an important consideration. This article reviews the methods for defining HRQOL, the challenges in measuring HRQOL in bladder cancer, and the literature comparing HRQOL after various methods of urinary diversion. Recent contributions include the validation of HRQOL instruments specific to bladder c...

  16. Physical activity, health-related quality of life and depression during pregnancy

    OpenAIRE

    Iva Tendais; Bárbara Figueiredo; Jorge Mota; Ana Conde

    2011-01-01

    This study examines physical activity patterns among women, from pre-pregnancy to the second trimester of pregnancy, and the relationship between physical activity status based on physical activity guidelines and health-related quality of life (HRQoL) and depression over pregnancy. 56 healthy pregnant women self-reported physical activity, HRQoL and depression at 10-15 and 19-24 weeks of pregnancy and physical activity before pregnancy. Whereas vigorous leisure physical activity decreased aft...

  17. The Effect of Hepatitis C Virus Infection on Health-Related Quality of Life in Prisoners

    OpenAIRE

    Thein, Hla-Hla; Butler, Tony; Krahn, Murray; Rawlinson, William; Levy, Michael H.; Kaldor, John M.; Dore, Gregory J

    2006-01-01

    Hepatitis C virus (HCV) infection in prisoners represents an important public health problem. However, there is very little information about HCV-related health-related quality of life (HRQOL). We examined the effect of HCV antibody positivity, HCV viremia, and being a prisoner on prisoners'' HRQOL. Population-based health surveys incorporating HCV screening were conducted among prisoners at New South Wales (NSW), Australia, correctional centers in 1996 and 2001. HCV antibody and HCV RNA stat...

  18. Bayesian predictors of very poor health related quality of life and mortality in patients with COPD

    OpenAIRE

    Ryynänen, Olli-Pekka; Soini, Erkki J.; Lindqvist, Ari; Kilpeläinen, Maritta; Laitinen, Tarja

    2013-01-01

    Background Chronic obstructive pulmonary disease (COPD) is associated with increased mortality and poor health-related quality of life (HRQoL) compared with the general population. The objective of this study was to identify clinical characteristics which predict mortality and very poor HRQoL among the COPD population and to develop a Bayesian prediction model. Methods The data consisted of 738 patients with COPD who had visited the Pulmonary Clinic of the Helsinki and Turku University Hospit...

  19. Religiousness and health-related quality of life of older adults

    Science.gov (United States)

    Abdala, Gina Andrade; Kimura, Miako; Duarte, Yeda Aparecida de Oliveira; Lebrão, Maria Lúcia; dos Santos, Bernardo

    2015-01-01

    OBJECTIVE To examine whether religiousness mediates the relationship between sociodemographic factors, multimorbidity and health-related quality of life of older adults. METHODS This population-based cross-sectional study is part of the Survey on Health, Well-Being, and Aging (SABE). The sample was composed by 911 older adults from Sao Paulo, SP, Southeastern Brazil. Structural equation modeling was performed to assess the mediator effect of religiousness on the relationship between selected variables and health-related quality of life of older adults, with models for men and women. The independent variables were: age, education, family functioning and multimorbidity. The outcome variable was health-related quality of life of older adults, measured by SF-12 (physical and mental components). The mediator variables were organizational, non-organizational and intrinsic religiousness. Cronbach’s alpha values were: physical component = 0.85; mental component = 0.80; intrinsic religiousness = 0.89 and family APGAR (Adaptability, Partnership, Growth, Affection, and Resolve) = 0.91. RESULTS Higher levels of organizational and intrinsic religiousness were associated with better physical and mental components. Higher education, better family functioning and fewer diseases contributed directly to improved performance in physical and mental components, regardless of religiousness. For women, organizational religiousness mediated the relationship between age and physical (β = 2.401, p < 0.01) and mental (β = 1.663, p < 0.01) components. For men, intrinsic religiousness mediated the relationship between education and mental component (β = 7.158, p < 0.01). CONCLUSIONS Organizational and intrinsic religiousness had a beneficial effect on the relationship between age, education and health-related quality of life of these older adults. PMID:26274870

  20. Health-related quality of life of among elders in rural China: the effect of widowhood.

    OpenAIRE

    Zhou, J.; Hearst, N

    2016-01-01

    China has an enormous and rapidly growing population of widowed elders. Little is known about how losing a spouse affects elders' health-related quality of life (QOL), especially in the rural areas where most Chinese elders live. This article analyzes QOL data collected in 2014 among rural Chinese elders to address this question.SF12 questionnaires and information about individual and household characteristics were collected from 3053 elders aged 60 and above in rural China. We compared the p...

  1. Health-Related Quality of Life and its Predictive Factors among Infertile Women

    OpenAIRE

    Mohammad Alizadeh Charandabi, Sekineh; Kamalifard, Mahin; Mahzad Sedaghiani, Mehrzad; Montazeri, Ali; Dehghanpour Mohammadian, Elham

    2012-01-01

    Introduction: The present study aimed to determine health-related quality of life (HRQOL) and its predictive factors among infertile women. Methods: This cross-sectional study was conducted on infertile women referring to Majidi Infertility Center (Tabriz, Iran). The data was collected through self-administered questionnaires including clinical and demographic characteristics and the Persian version of 36-item short form health survey (SF-36). One-sample t-test, independent ...

  2. Disordered Eating and Health-Related Quality of Life in Overweight and Obese Children

    OpenAIRE

    Gowey, Marissa A.; Lim, Crystal S.; Clifford, Lisa M.; Janicke, David M.

    2014-01-01

    Objectives To examine disordered eating and associations with health-related quality of life (HRQOL) in rural overweight/obese (OW/OB) children. Methods Cross-sectional analyses were conducted with 272 rural OW/OB children aged 8–12 years (M = 10.36; SD = 1.39). Child anthropometrics, demographics, disordered eating attitudes, unhealthy weight control behaviors (UWCBs), and HRQOL were measured. Relationships between these variables were analyzed using bootstrapped multiple linear regressions....

  3. Testing the applicability of a model of oral health-related quality of life.

    Science.gov (United States)

    Santos, Camila Mello Dos; Celeste, Roger Keller; Hilgert, Juliana Balbinot; Hugo, Fernando Neves

    2015-09-01

    The aim of this study was to test Wilson & Cleary's conceptual model of the direct and mediated pathways between clinical and non-clinical variables in relation to oral health-related quality of life. A random sample of 578 older people was evaluated. Wilson & Cleary's conceptual model was tested using structural equations modeling including: biological variables, symptom status, functional health, oral health perceptions, oral health-related quality of life. Oral health-related quality of life was assessed with the Oral Health Impact Profile-14 (OHIP-14). In the final model, edentulism was negatively correlated to dissatisfaction of appearance of their dental prostheses (r = -0.25). Worse functional status was correlated with poor oral health perception (r = 0.24). Being aged over 68 (r = 0.25), being a female (r = 0.39) and living in rural areas (r = 0.15) had a direct effect on the edentulism. Age had a direct effect on OHIP-14 (r = -0.15). There was an indirect effect of sex on OHIP-14 via functional status (r = 0.12). The present findings partially support Wilson & Cleary's model framework. PMID:26578012

  4. Testing the applicability of a model of oral health-related quality of life

    Directory of Open Access Journals (Sweden)

    Camila Mello dos Santos

    2015-09-01

    Full Text Available The aim of this study was to test Wilson & Cleary’s conceptual model of the direct and mediated pathways between clinical and non-clinical variables in relation to oral health-related quality of life. A random sample of 578 older people was evaluated. Wilson & Cleary’s conceptual model was tested using structural equations modeling including: biological variables, symptom status, functional health, oral health perceptions, oral health-related quality of life. Oral health-related quality of life was assessed with the Oral Health Impact Profile-14 (OHIP-14. In the final model, edentulism was negatively correlated to dissatisfaction of appearance of their dental prostheses (r = -0.25. Worse functional status was correlated with poor oral health perception (r = 0.24. Being aged over 68 (r = 0.25, being a female (r = 0.39 and living in rural areas (r = 0.15 had a direct effect on the edentulism. Age had a direct effect on OHIP-14 (r = -0.15. There was an indirect effect of sex on OHIP-14 via functional status (r = 0.12. The present findings partially support Wilson & Cleary’s model framework.

  5. Health-related quality of life in polycystic ovary syndrome patients: A systematic review

    Directory of Open Access Journals (Sweden)

    Seyed Abdolvahab Taghavi

    2015-08-01

    Full Text Available Background: Increasing attention to the concept of polycystic ovary syndrome (PCOS health-related quality of life has led to the development of tool that aims to measure this concept. Objective: The purpose of this study was to conduct a systematic review of psychometric properties of the PCOS health-related quality of life questionnaire. Materials and Methods: A search of database (Pubmed, PsychInfo, CINAHL, CENTRAL, Scopus and SID from January1998 to December 2013 yielded 6152 references of which 27 papers remained after review of the titles and abstracts. The reviewers used structural tools to analyze the articles, critically appraise papers, and extract the data. Finally, eight papers met the full inclusion criteria. Results: Studies suggested that the PCOS health-related quality of life questionnaire (PCOSQ/or its modified version (MPCOSQ have partial known groups validity. The convergent/divergent validity of the questionnaire also was found to be relatively acceptable. The PCOSQ/MPCOSQ reached acceptable benchmarks for its reliability coefficients. Regarding structural validity, some studies suggested that the PCOSQ/MPCOSQ have an extra dimension (related to menstruation in addition to its existing dimensions for original or modified versions. Conclusion: The PCOSQ/MPCOSQ showed acceptable content and construct validity, reliability and internal consistency. However, some other properties, particularly those related to factor and longitudinal validity, absolute error of measurement, minimal clinically important difference and responsiveness still need to be evaluated.

  6. Narrative review of health-related quality of life and its predictors among patients with coronary heart disease.

    Science.gov (United States)

    Muhammad, Imran; He, Hong-Gu; Kowitlawakul, Yanika; Wang, Wenru

    2016-02-01

    This paper summarizes the empirical evidence concerning health-related quality of life (HRQoL) of patients with coronary heart disease (CHD) and attempts to identify its significant predictors. A systematic search of the literature from 2002 to 2012 was conducted using seven electronic databases (CINAHL, ScienceDirect, Medline, Scopus, PsycINFO, PubMed and Web of Science) using the search terms 'HRQoL'. 'CHD', 'social support', 'depression', 'anxiety', 'psychosocial factors', 'sociodemographic factors', 'clinical factors' and 'predictors'. A total of 1052 studies were retrieved, of which 24 articles were included in this review. Previous studies have consistently demonstrated the negative impact of CHD on HRQoL, citing three major types of predictive factors: sociodemographic, clinical and psychosocial factors. Studies have also highlighted the advantageous use of HRQoL as a gauge for treatment satisfaction and efficacy. There are, however, few studies that collectively investigate the relationship among concepts such as HRQoL, anxiety and depression, social support, and sociodemographic and clinical factors in relation to CHD. This review highlights the need to conduct further study on HRQoL of patients with CHD in the Asian context. Such research will promote patient-centric care and improved patient satisfaction through incorporation of the concept of HRQoL into clinical practice. PMID:25039442

  7. Decreased health-related quality of life in disease-free survivors of differentiated thyroid cancer in Korea

    Directory of Open Access Journals (Sweden)

    Kim Kwang-Won

    2010-09-01

    Full Text Available Abstract Background Concern regarding the health-related quality of life (HRQOL of long-term survivors of thyroid cancer has risen due to the rapid increase in the incidence of thyroid cancer, which generally has an excellent prognosis. The aim of this study was to evaluate the status of HRQOL in disease-free survivors of differentiated thyroid carcinoma (DTC and to evaluate the important determinants of HRQOL. Methods This was a cross-sectional study in which we interviewed consecutive disease-free survivors of DTC. Three different validated questionnaires ("EORTC QLQ-C30" for various functional domains, the "brief fatigue inventory (BFI" and the "hospital anxiety and depression scale" (HADS were used. Data from a large, population based survey of 1,000 people were used as a control. Results The response rate for the questionnaires was 78.9% (316/401. Disease-free survivors of DTC showed a decreased HRQOL in all five functional domains (physical, role, cognitive, emotional, and social on the EORTC QLQ-C30 compared with controls (P P Conclusions Although disease-free survivors of DTC are expected to have disease-specific survival comparable to the general population, they experience a significantly decreased HRQOL. Anxiety, depression, and fatigue were the major determinants of the decreased HRQOL. Supportive psychological care should be integrated into the management of long-term survivors of DTC.

  8. Health-related quality of life of patients six months poststroke living in the Western Cape, South Africa

    Directory of Open Access Journals (Sweden)

    Anthea J. Rhoda

    2014-04-01

    Full Text Available Background: The majority of individuals report a decline in health-related quality of life following a stroke. Quality of life and factors predicting quality of life could differ in individuals from lower income countries. The aim of this study was therefore to determine the quality of life and factors influencing quality of life of community-dwelling stroke patients living in low-income, peri-urban areas in the Western Cape, South Africa.Method: An observational, longitudinal study was used to collect data from a conveniently selected sample of first-ever stroke patients. The Rivermead Motor Assessment Scale and the Barthel Index were used to determine functional outcome and the EQ-5D was used to collect information relating to quality of life at two months and six months poststroke. Descriptive and inferential statistics were used to analyse the data.Results: The total sample of 100 participants consisted of 50% men and 50% women with a mean age of 61 and a standard deviation of 10.55 years. Six-month quality of life datawas analysed for 73 of the 100 participants. Of the 27 who were lost to follow-up, nine participants died, four withdrew from the study after baseline data was collected and eleven could not be followed up as they had either moved or no follow-up telephone numbers were available. A further three participants were excluded from the analysis of the EQ-5D as they were aphasic. Of these, approximately 35% had problems with mobility and self-care, whilst 42% had severe problems with everyday activities and 37.8% expressed having anxiety and depression. Quality of life at two months (p = 0.010 and urinary incontinence (p = 0.002 were significant predictors of quality of life at six months.Conclusion: Health-related quality of life was decreased in the South African stroke sample. Functional ability and urinary incontinence were the factors affecting quality of life in the sample. These factors should be considered in the

  9. Implementing Health Related Quality of Life Measurement in Clinical Practice: A prospective study in patients with chronic liver disease

    NARCIS (Netherlands)

    J.J. Gutteling (Jolie)

    2008-01-01

    textabstractHealth related quality of life (HRQoL), or psychological-, social-, and physical functioning (1), has become an important outcome measure in medical care. A literature search in PubMed in July 2007 for ‘health related quality of life’ showed close to 14.000 hits. Until recently, HRQoL me

  10. Does mode of administration affect health-related quality-of-life outcomes after stroke?

    OpenAIRE

    Caute, A.; Northcott, S.; Clarkson, L.; Pring, T.; Hilari, K.

    2012-01-01

    Telephone interviews and postal surveys may be a resource-efficient way of assessing health-related quality-of-life post-stroke, if they produce data equivalent to face-to-face interviews. This study explored whether telephone interviews and postal surveys of the Stroke and Aphasia Quality of Life Scale (SAQOL-39g) yielded similar results to face-to-face interviews. Participants included people with aphasia and comprised two groups: group one (n =22) were 3-6 months post-stroke; group two (n ...

  11. Parental reports of the oral health-related quality of life of children with cerebral palsy

    OpenAIRE

    Abanto Jenny; Carvalho Thiago S; Bönecker Marcelo; Ortega Adriana OL; Ciamponi Ana L; Raggio Daniela P

    2012-01-01

    Abstract Background The severity of physical and mental impairments and oral problems, as well as socioeconomic factors, may have an impact on quality of life of children with cerebral palsy (CP). The aim of this research was to assess the impact of impairments and oral health conditions, adjusted by socioeconomic factors, on the Oral Health-Related Quality of Life (OHRQoL) of children with CP using their parents as proxies. Methods Sixty children, between 6-14 years of age were selected. The...

  12. Oral health related quality of life in Indonesian middle-aged and elderly women

    OpenAIRE

    Lindawati S. Kusdhany; Yuliana Sundjaja; Sitti Fardaniah; Raden I. Ismail

    2011-01-01

    Background: To assess oral health-related quality of life in Indonesian middle-aged and elderly women. Middle–aged women between 45-59 years old were included in this study, because this stage of life is important to prepare them  entering the old age. Prevention could be done earlier in order to achieve optimum quality of life for the elderly. The purpose of writing this paper is to inform the policy maker to develop a framework in oral health prevention.Method: Cross-sectional study was don...

  13. Employment Is Associated with the Health-Related Quality of Life of Morbidly Obese Persons

    OpenAIRE

    Lund, Randi Størdal; Karlsen, Tor-Ivar; Hofsø, Dag; Fredheim, Jan Magnus; Røislien, Jo; Sandbu, Rune; Hjelmesæth, Jøran

    2010-01-01

    Background  We aimed to investigate whether employment status was associated with health-related quality of life (HRQoL) in a population of morbidly obese subjects. Methods  A total of 143 treatment-seeking morbidly obese patients completed the Medical Outcome Study 36-Item Short-Form Health Survey (SF-36) and the Obesity and Weight-Loss Quality of Life (OWLQOL) questionnaires. The former (SF-36) is a generic measure of physical and mental health status and the latter (OWLQOL) an obesity-spec...

  14. Bilateral subthalamic nucleus stimulation improves health-related quality of life in Parkinsonian patients.

    Science.gov (United States)

    Erola, Tuomo; Karinen, Petri; Heikkinen, Esa; Tuominen, Juho; Haapaniemi, Tarja; Koivukangas, John; Myllylä, Vilho

    2005-03-01

    Parkinson's disease (PD) is a common neurological disorder. Recently, bilateral deep brain stimulation (DBS) of the subthalamic nucleus (STN) has become an option in the treatment of severe PD. We measured the health-related quality of life (HRQoL) of 27 parkinsonian patients, who underwent a bilateral STN-operation. The instruments used for the evaluation of the HRQoL were the Parkinson's Disease Questionnaire (PDQ-39) and the Finnish version of the Nottingham Health Profile (NHP). We found that the quality of life significantly improved when measured with both HRQoL scales. Clinical improvement and improvement in HRQoL were positively correlated. PMID:15734666

  15. Pain, psychological distress and health-related quality of life at baseline and 3 months after radical prostatectomy

    Directory of Open Access Journals (Sweden)

    Johansson Fannie

    2006-11-01

    Full Text Available Abstract Background Inadequate management of postoperative pain is common, and postoperative pain is a risk factor for prolonged pain. In addition to medical and technical factors, psychological factors may also influence the experience of postoperative pain. Methods Pain was measured postoperatively at 24, 48, and 72 hr in hospital and after 3 months at home in 140 patients undergoing radical prostatectomy (RP. Patients answered questionnaires about anxiety and depression (HAD scale and health-related quality of life (SF-36 at baseline and 3 months after surgery. Results In the first 3 postoperative days, mild pain was reported by 45 patients (32%, moderate pain by 64 (45%, and severe pain by 31 (22% on one or more days. High postoperative pain scores were correlated with length of hospital stay and with high pain scores at home. Forty patients (29% reported moderate (n = 35 or severe (n = 5 pain after discharge from hospital. Patients who experienced anxiety and depression preoperatively had higher postoperative pain scores and remained anxious and depressed 3 months after surgery. The scores for the physical domains in the SF-36 were decreased, while the mental health scores were increased at 3 months. Anxiety and depression were negatively correlated with all domains of the SF-36. Conclusion There is a need for nurses to be aware of the psychological status of RP patients and its impact upon patients' experience of postoperative pain and recovery. The ability to identify patients with psychological distress and to target interventions is an important goal for future research.

  16. Measuring health-related quality of life in men with osteoporosis or osteoporotic fracture

    Directory of Open Access Journals (Sweden)

    Solà Silvia

    2011-10-01

    Full Text Available Abstract Background Osteoporosis is a serious health problem that worsens the quality of life and the survival rate of individuals with this disease on account the osteoporotic fractures. Studies have long focused on women, and its presence in men has been underestimated. While many studies conducted in different countries mainly assess health-related quality of life and identify fracture risks factors in women, few data are available on a Spanish male population. Methods/Design Observational study. Study population Men ≥ 40 years of age with/without diagnosed osteoporosis and with/without osteoporotic fracture included by their family doctor. Measurements The relationship between customary clinical risk factors for osteoporotic fracture and health-related quality of life in a Spanish male population. A telephone questionnaire on health-related quality of life is made. Statistical analysis The association between qualitative variables will be assessed by the Chi-square test. The distribution of quantitative variables by Student's t-test. If the conditions for using this test are not met, the non-parametric Mann-Whitney's U test will be used. The validation of the results obtained by the FRAX™ tool will be performed by way of the Hosmer-Lemeshow test and by calculating the area under the Receiver Operating Characteristic (ROC curve (AUC. All tests will be performed with a confidence intervals set at 95%. Discussion The applicability and usefulness of Health-related quality of life (HRQOL studies are well documented in many countries. These studies allow implementing cost-effective measures in cases of a given disease and reducing the costly consequences derived therefrom. This study attempts to provide objective data on how quality of life is affected by the clinical aspects involved in osteoporosis in a Spanish male population and can be useful as well in cost utility analyses conducted by health authorities. The sample selected is not based

  17. Determinants of disease-specific health-related quality of life in Turkish stroke survivors.

    Science.gov (United States)

    Safaz, İsmail; Kesikburun, Serdar; Adigüzel, Emre; Yilmaz, Bilge

    2016-06-01

    Stroke is a worldwide cause of morbidity and mortality that affects health-related quality of life. In this study, our objective was to identify determinants of disease-specific health-related quality of life in Turkish stroke survivors. A total of 114 consecutive patients who experienced a stroke at least 6 months earlier were studied. Health-related quality of life was measured using Stroke-specific Quality of Life (SS-QoL) consisting of 12 domains. Demographic and clinical data were collected, including age, sex, marital status, years of education, time since stroke, whether the patient received rehabilitation before enrollment, stroke etiology, whether the dominant hand was affected or not, presence of vision defect, neglect, aphasia, and dysarthria. The patients were assessed by the functional independence measure (FIM) and the Mini-Mental State Examination. A multiple linear regression analysis was carried out using a stepwise method to determine the predictors of 12 domains and the total score of the SS-QoL. The domains of work, social roles, mobility, and self-care had the lowest SS-QoL scores, whereas the highest scores were for the domains of personality, thinking, language, and vision. The total SS-QoL score was explained by the total FIM and Mini-Mental State Examination. Among the 12 domains, the mobility domain was explained the best (R=0.50) by motor FIM, previously received rehabilitation, and age, followed by the language domain (R=0.37) explained by the presence of aphasia and dysarthria, and previously received rehabilitation. The domains of mood (R=0.13) and upper extremity (R=0.19) were explained the worst. The results indicated that functional independence, age, cognitive status, and receiving a rehabilitation program were the primary determinants of the SS-QoL. PMID:26795717

  18. Health-related quality of life of irritable bowel syndrome patients in different cultural settings

    Directory of Open Access Journals (Sweden)

    Johansson Saga

    2006-03-01

    Full Text Available Abstract Background Persons with Irritable bowel syndrome (IBS are seriously affected in their everyday life. The effect across different cultural settings of IBS on their quality of life has been little studied. The aim was to compare health-related quality of life (HRQOL of individuals suffering from IBS in two different cultural settings; Crete, Greece and Linköping, Sweden. Methods This study is a sex and age-matched case-control study, with n = 30 Cretan IBS cases and n = 90 Swedish IBS cases and a Swedish control group (n = 300 randomly selected from the general population. Health-related quality of life, measured by SF-36 and demographics, life style indicators and co-morbidity, was measured. Results Cretan IBS cases reported lower HRQOL on most dimensions of SF-36 in comparison to the Swedish IBS cases. Significant differences were found for the dimensions mental health (p Conclusion The results from this study tentatively support that the claim that similar individuals having the same disease, e.g. IBS, but living in different cultural environments could perceive their disease differently and that the disease might affect their everyday life and quality of life in a different way. The Cretan population, and especially women, are more seriously affected mentally by their disease than Swedish IBS cases. Coping with IBS in everyday life might be more problematic in the Cretan environment than in the Swedish setting.

  19. Pessary treatment for pelvic organ prolapse and health-related quality of life: a review

    OpenAIRE

    Lamers, Babet H. C.; Broekman, Bart M. W.; Milani, Alfredo L.

    2011-01-01

    Pessaries have been used to treat women with pelvic organ prolapse (POP) since the beginning of recorded history. This review aims to assess the effect of pessary treatment on the disease-specific, health-related quality of life in women with pelvic organ prolapse. After a Medline search using the Mesh term ‘pessary’ and critical appraisal, 41 articles were selected and used in this review. Pessaries are widely used to treat pelvic organ prolapse. It is minimally invasive and appears to be sa...

  20. Health-related quality of life of children and adolescents with mental disorders

    OpenAIRE

    Weitkamp, Katharina; Daniels, Judith K.; Romer, Georg; Wiegand-Grefe, Silke

    2013-01-01

    Background The aim was to assess the association of internalising and externalising pathology with the child’s health-related quality of life (QoL), and to determine which child and environmental characteristics beyond pathology were related to poor QoL. Methods Data was obtained for 120 children and adolescents (aged 6 to 18) commencing outpatient psychotherapy treatment. Parents and children (aged 11 years and older) filled out questionnaires. QoL was measured with the KIDSCREEN-27. Results...

  1. Oral Health-related Quality of Life: What, Why, How, and Future Implications

    OpenAIRE

    Sischo, L.; Broder, H.L.

    2011-01-01

    Despite its relatively recent emergence over the past few decades, oral health-related quality of life (OHRQoL) has important implications for the clinical practice of dentistry and dental research. OHRQoL is a multidimensional construct that includes a subjective evaluation of the individual’s oral health, functional well-being, emotional well-being, expectations and satisfaction with care, and sense of self. It has wide-reaching applications in survey and clinical research. OHRQoL is an int...

  2. Health-related quality of life in long-term survivors of testicular cancer

    DEFF Research Database (Denmark)

    Rossen, Philip Blach; Pedersen, Anette Fischer; Zachariae, Robert;

    2009-01-01

    PURPOSE: A growing number of patients with testicular cancer (TC) become long-term survivors. As a consequence, quality-of-life (QOL) issues become increasingly important. The objective of this study was to investigate QOL among Danish TC survivors. METHODS: A long-term follow-up assessment of all...... Depression Inventory-II), fatigue (Multidimensional Fatigue Inventory-20), and health-related issues such as neurotoxic symptoms and Raynaud-like phenomena. On the basis of their treatment, participants were categorized as having received surveillance, radiotherapy, or chemotherapy. RESULTS: QOL among...

  3. Health-Related Quality of Life of Nigerian Children with Cerebral Palsy

    OpenAIRE

    A E Ogunrinu; Oluwaseyi Abigail Osho; Caleb Ademola Gbiri; Bosede Abidemi Tella

    2011-01-01

    Purpose: To assess the impact of cerebral palsy on health-related quality of life (HRQoL) of Nigerian children.Method: This is a cross-sectional survey. The study involved 54 children (33 males and 21 females), between 1 and 12 years of age, with cerebral palsy. They were consecutively recruited from two tertiary health institutions in Lagos, Nigeria. The socio-demographic details of the participants were obtained through interviews. Their HRQoL was assessed using the Child Health Questionnai...

  4. Smoking and health-related quality of life in English general population: Implications for economic evaluations

    OpenAIRE

    Vogl Matthias; Wenig Christina M; Leidl Reiner; Pokhrel Subhash

    2012-01-01

    Abstract Background Little is known as to how health-related quality of life (HRQoL) when measured by generic instruments such as EQ-5D differ across smokers, ex-smokers and never-smokers in the general population; whether the overall pattern of this difference remain consistent in each domain of HRQoL; and what implications this variation, if any, would have for economic evaluations of tobacco control interventions. Methods Using the 2006 round of Health Survey for England data (n = 13,241),...

  5. General self-efficiacy and health-related quality of life after myocardial infarction

    OpenAIRE

    Brink, Eva; Alsén, Pia; Herlitz, Johan; Kjellgren, Karin; Cliffordson, Christina

    2012-01-01

    Fatigue after myocardial infarction (MI) has been found to be distressing. A person's self-efficacy will influence his/her health behavior and plays an active role in tackling illness consequences. This study investigated associations between fatigue, disturbed sleep, general self-efficacy, and health-related quality of life (HRQoL) in a sample of 145 respondents admitted to hospital for MI two years earlier. The aim was to identify the predictive value of general self-efficacy and to elucida...

  6. Health-related quality of life of patients with rheumatoid arthritis. Which factors are of significance?

    DEFF Research Database (Denmark)

    Linde, L.; Sørensen, J.; Ostergaard, M.; Hetland, M.L.

    2008-01-01

    Rheumatoid arthritis (RA) is a chronic inflammatory disease causing joint pain, loss of function and decreased health-related quality of life (HRQoL). HRQoL in RA patients is associated with several risk factors; in this paper the evidence relating to the most important risk factors is reviewed....... Modern medical therapy has improved HRQoL in RA patients, while demographic factors (female sex and older age), low socioeconomic status (in terms of education and position in the work force) and the presence of comorbid conditions appear to be associated with poorer HRQoL Udgivelsesdato: 2008/3/3...

  7. Health-related quality of life of child and adolescent retinoblastoma survivors in the Netherlands

    OpenAIRE

    Bezemer Pieter D; Schouten-van Meeteren Antoinette YN; Moll Annette C; Huisman Jaap; van Dijk Jennifer; Ringens Peter J; Cohen-Kettenis Peggy T; Imhof Saskia M

    2007-01-01

    Abstract Background To assess health-related quality of life (HRQoL) in children (8–11 years) and adolescents (12–18 years) who survived retinoblastoma (RB), by means of the KIDSCREEN self-report questionnaire and the proxy-report version. Methods This population-based cross-sectional study (participation rate 70%) involved 65 RB survivors (8–18 years) and their parents. Child/adolescents' and parents' perception of their youth's HRQoL was assessed using the KIDSCREEN, and the results were co...

  8. Health-related quality of life in patients with Chagas disease

    OpenAIRE

    Bruna Guimarães Oliveira; Mery Natali Silva Abreu; Claudia Drummond Guimarães Abreu; Manoel Otavio da Costa Rocha; Antonio Luiz Ribeiro

    2011-01-01

    INTRODUCTION: Chagas disease (ChD) is a chronic illness related to significant morbidity and mortality that can affect the quality of life (QoL) of infected patients. However, there are few studies regarding QoL in ChD. The objectives of this study are to construct a health-related QoL (HRQoL) profile of ChD patients and compare this with a non-ChD (NChD) group to identify factors associated with the worst HRQoL scores in ChD patients. METHODS: HRQoL was investigated in 125 patients with ChD ...

  9. Oral health-related quality of life in an aging Canadian population

    OpenAIRE

    Kotzer Robert D; Lawrence Herenia P; Clovis Joanne B; Matthews Debora C

    2012-01-01

    Abstract Background The purpose of the study is to describe the impact of oral health-related quality of life (OHRQoL) on the lives of pre-seniors and seniors living in Nova Scotia, Canada. Methods This cross-sectional study involved 1461 participants, grouped by age (pre-seniors [45–64] and seniors [65+]) and residential status (long-term care facility [LTC] or community). OHRQoL was measured using the 14-item Oral Health Impact Profile questionnaire (OHIP-14) in a random digit dialing telep...

  10. Health-Related Quality of Life and Overall Life Satisfaction in People with Serious Mental Illness

    OpenAIRE

    Amy L. Barnes; Murphy, Meghan E.; Fowler, Christopher A.; Rempfer, Melisa V.

    2012-01-01

    Quality of life (QoL) in people with schizophrenia and other serious mental illnesses (SMI) is an important outcome goal, yet there is no consistent definition of the construct. We examined three aspects of QoL in persons with SMI: overall life satisfaction, physical health-related QoL (HRQoL), and mental HRQoL. This study had two primary aims: first, to examine whether there are differences in physical and mental HRQoL in persons with SMI, and, second, to investigate the cognitive, clinical,...

  11. Is hypoglycemia fear independently associated with health-related quality of life?

    OpenAIRE

    Shi, Lizheng; Shao, Hui; Zhao, Yingnan; Thomas, Nina A

    2014-01-01

    Objective Patients may fear the symptoms and consequences associated with hypoglycemia. We tested whether fear of hypoglycemia is independently associated with poorer health-related quality of life (HRQOL). Research design and methods Data were collected using direct-mail survey and enrollment information from adult commercial health plan enrollees with type 2 diabetes during a 12-month period (12/01/2008 to 11/30/2009). HRQOL was evaluated by the EuroQol (EQ)–5D index and 12-item Short Form ...

  12. Coronary artery bypass graft (CABG) surgery patients in a clinical pathway gained less in health-related quality of life as compared with patients who undergo CABG in a conventional-care plan

    NARCIS (Netherlands)

    El Baz, Noha; Middel, Berrie; van Dijk, Jitse P.; Boonstra, Piet W.; Reijneveld, Sijmen A.

    2009-01-01

    The aim of this study is to determine the difference between clinical pathway (CP) and conventional care in terms of health-related quality of life (HRQoL) domains, depression and anxiety, as well as to determine the relative contribution of CP towards an improved HRQoL after coronary artery bypass

  13. Health-related quality of life after surgery for hip fracture: a multicentric study in Mexican population

    Directory of Open Access Journals (Sweden)

    Esperanza Ramírez-Pérez

    2014-06-01

    Full Text Available INTRODUCTION Hip fractures are an important cause of morbidity and mortality and one of the main causes of disability in the older population. The lifetime risk for any type of osteoporotic fracture is very high and falls within the range of 40–50% in women and 13–22% for men. In Mexico, the lifetime likelihood of having a hip fracture at 50 years of age is 8.5% in Mexican women and 3.8% in Mexican men, but this is expected to rise in upcoming years. AIM This study aims to report the Health-Related Quality of Life over the first six months after a hip fracture in two public and two private tertiary care hospitals in Mexico City. METHOD Changes over time were evaluated through visual observation of each patient’s development trajectory using the graphic representation of the EQ-5D global score. The trajectories were grouped by affinity into five levels of progress according to clinical course. The identified descriptive options were analyzed using the multinomial logistic regression model (LR. RESULTS One-hundred-and-thirty-six (136 patients with a hip fracture were followed after surgery. Their mean age was 77 ± 10 years. During the first month, mobility, daily activities, and self-care were the most affected. The group aged between 80 and 84 years reported extreme problems regarding anxiety and depression (21%, and those aged between 50 and 74 years described having issues concerning pain and discomfort (27%. At the 6-month follow-up, only those aged > 85 years of age showed worsening of their condition, a high proportion of these ranking at level 3 in mobility, self-care, and anxiety/depression. Toward the end of the follow-up period, this last group reported having extreme problems (being unable to carry out everyday activities and worsening of their mobility (9.2% (inability to walk about (LR test, p = 0.06. DISCUSSION Patients with hip fracture showed difficulties in different areas during the first month after surgery, with steady

  14. The Role of Personality and Social Support in Health-Related Quality of Life in Chronic Kidney Disease Patients

    OpenAIRE

    Ibrahim, Norhayati; Teo, Sharlene S. L.; Che Din, Normah; Abdul Gafor, Abdul Halim; Ismail, Rozmi

    2015-01-01

    Background Chronic kidney disease (CKD) is commonly associated with various negative health outcomes. The aim of this study was to examine the influence of personality and social support on health-related quality of life in patients with chronic kidney disease. Health-related quality of life (HRQoL) is the quality of life studied in relation to health, and it provides important information of patients’ coping with their health issues. Method Participants comprised of 200 patients experiencing...

  15. Health Related Quality of Life in Elderly People Living in Bandar Abbas, Iran: A Population-Based Study

    OpenAIRE

    Teamur Aghamolaei; Sedigheh Sadat Tavafian; Shahram Zare

    2010-01-01

    "nMeasuring health related quality of life of old people has become an important public health issue with the aging of population in developing countries. The aim of this study was to examine the health related quality of life of old people living in Bandar Abbas, Iran. This was a population-based study in which a random sample of 1000 individuals of the community aged over 60 years were interviewed using SF-36 questionnaire. Overall health related quality of life and relative difference...

  16. Assessment of health-related quality of life in patients after acute myocardial infarction

    Directory of Open Access Journals (Sweden)

    Rančić Nataša

    2011-01-01

    Full Text Available Introduction. Acute myocardial infarction has negative influence on patient’s quality of life. The objective of the paper was to assess the healthrelated quality of life in the patients one month and twelve months after acute myocardial infarction and to compare it with the healthy controls. Material and Methods. A prospective cohort study involved 160 patients aged from 30 to 79 and 240 healthy controls. The health-related quality of life was assessed with the Serbian version of these questionnaires: Euro- Quol-5-Dimension and EuroQuolVAS. Angina pectoris was ranked according to the classification of Canadian Cardiovascular Society. Multivariate logistic regression analysis was used. Results. The healthy controls had significantly higher average scores in EuroQuolVAS compared with the patients one month after acute myocardial infarction (74.35±9.42 vs 60.50±12.03, p<0.001, as well as twelve months after acute myocardial infarction (74.35±9.42 vs 69.83±12.06, p<0.001. Significantly lower average ranges in EuroQuol-5-Dimension questionnaire and higher quality of life were found twelve months after acute myocardial infarction than one month after acute myocardial infarction (1.41±0.26 vs 1.53±0.26, p<0.001. The average ranges of angina pectoris were significantly lower in all the patients twelve months after acute myocardial infarction compared with the first month (0.78±0.51 vs 0.91±0.44, p<0.001. The multivariate regression analysis confirmed thrombolytic therapy, percutaneous transluminal angioplasty and age to be important factors influencing health-related quality of life. Conclusion. The patients assessed their health condition to be significantly higher twelve months after acute myocardial infarction than one month after it. The health-related quality of life was significantly higher in patients who had undergone the percutaneous intervention than in those who had been treated with the thrombolytic therapy.

  17. The Association Between Functional Status, Health Related Quality of Life and Depression After Stroke

    Directory of Open Access Journals (Sweden)

    Özlem Altındağ

    2008-10-01

    Full Text Available Objective: Stroke is a major cause of disability, and assessment of quality of life is important in patients after suffering a stroke. Psychological disorders may be associated with poor quality of life and lower functional status after stroke. The objective of the study was to determine the relation between health-related quality of life, functional status, and depressive symptoms in stroke patients. Materials and Methods: Subjects consisted of fourty patients who were being treated in the rehabilitation program in the Department of Physical Medicine and Rehabilitation at Harran University Research Hospital. Health-related quality of life was assessed using Short Form 36 (SF-36, functional status using the Stroke Adapted Sickness Impact Profile (SA-SIP, and depressive symptoms using Beck’s Depression Inventory (BDI.Results: BDI scores were negatively correlated with physical functioning, role limitations due to physical problems, emotional problems, and mental health subscales of SF-36 (p=0.002, r=-0.474; p=0.008, r=-0.417; p=0.01, r=-0.369; p=0.03, r=-0.369, respectively. Furthermore, BDI scores were positively correlated with Communication, Ambulation, and Emotional Behavior subscale scores of SA-SIP (p=0.03, r=0.347; p=0.002, r=0.483; p=0.001, r=0.502, respectively.Conclusion: Depressive symptoms are common, and the severity of depression may be related to poor functional status and quality of life in stroke patients. Assessment, recognition and management of depression may facilitate the participation of stroke patients in rehabilitation programs. Turk J Phys Med Rehab 2008;54:89-91.

  18. Health-related quality of life in persons with long-standing spinal cord injury

    DEFF Research Database (Denmark)

    Lidal, I.B.; Veenstra, M.; Hjeltnes, N.;

    2008-01-01

    STUDY DESIGN: A cross-sectional study of all patients with traumatic SCI admitted to Sunnaas Rehabilitation Hospital, Norway between 1961 and 1982. OBJECTIVES: To assess health-related quality of life (HRQOL) in persons with long-standing traumatic spinal cord injury (SCI) in Norway. SETTING: Sun...... reporting health problems or symptoms was worse than those of individuals reporting no health problems at all. CONCLUSION: HRQOL is decreased in persons with long-standing SCI and especially in persons with comorbidity conditions Udgivelsesdato: 2008/11......STUDY DESIGN: A cross-sectional study of all patients with traumatic SCI admitted to Sunnaas Rehabilitation Hospital, Norway between 1961 and 1982. OBJECTIVES: To assess health-related quality of life (HRQOL) in persons with long-standing traumatic spinal cord injury (SCI) in Norway. SETTING......: Sunnaas Rehabilitation Hospital, Norway. METHODS: Survey data and clinical examination of 165 persons with traumatic SCI of more than 20 years duration. HRQOL was assessed with the Norwegian 36-item short-form [corrected] (SF-36) Health Survey. The SF-36 results were compared with Norwegian norm data...

  19. Swedish population health-related quality of life results using the EQ-5D

    DEFF Research Database (Denmark)

    Burström, K; Johannesson, M; Diderichsen, F

    2001-01-01

    Health-related quality of life (HRQoL) measured on population level may be useful to guide policies for health. This study aims to describe the HRQoL; in EQ-5D dimensions, mean rating scale (RS) scores and mean EQ-5D index values, in the general population, by certain disease and socio-economic g......Health-related quality of life (HRQoL) measured on population level may be useful to guide policies for health. This study aims to describe the HRQoL; in EQ-5D dimensions, mean rating scale (RS) scores and mean EQ-5D index values, in the general population, by certain disease and socio......-economic groups, in Stockholm County 1998. The EQ-5D self-classifier and a RS were included in the 1998 cross-sectional postal Stockholm County public health survey to a representative sample (n = 4950, 20-88 years), 63% response rate. Mean RS score ranged from 0.90 (20-29 years) to 0.69 (80-88 years), mean EQ-5D...

  20. Associations between demographics and health-related quality of life for chronic non-malignant pain patients treated at a multidisciplinary pain centre

    DEFF Research Database (Denmark)

    Jensen, Hanne Irene; Plesner, Karin; Kvorning, Nina; Krogh, Bo Lunddal; Kimper-Karl, Alan

    2016-01-01

    OBJECTIVE: To describe the associations between demographics and health-related quality of life for chronic non-malignant pain patients. DESIGN: A cohort study. SETTING: A multidisciplinary Danish pain centre. STUDY PARTICIPANTS: All patients treated at the centre between 2007 and 2013. MAIN.......7 ± 14.4 (range 18-89), and 21% were able to work full or part time. On a Numeric Rating Scale from 0 to 10, median pain-intensity was 8 (interquartile range 7-8) and pain-discomfort 8 (interquartile range 7-9) at time of referral. More than half of the patients had symptoms of anxiety and depression...

  1. The sense-of-coherence predicts health-related quality of life and emotional distress but not disability in Parkinson’s disease

    OpenAIRE

    Gison, Annalisa; Rizza, Federica; Bonassi, Stefano; Dall’Armi, Valentina; Lisi, Stefania; Giaquinto, Salvatore

    2014-01-01

    Background Personality traits are deemed important in many fields of Medicine. The present study aimed at evaluating i) the presence of Sense-of-Coherence (SOC) in patients suffering from Parkinson’s Disease (PD) in comparison with an age-matched general control population, ii) the influence of SOC on health-related variables, such as depression and anxiety, quality of life (Qol), and activities of daily living (ADL). Methods SOC was measured in 50 PD patients and in 50 matched controls enrol...

  2. Urostomy and health-related quality of life in patients with lower urinary tract dysfunction

    DEFF Research Database (Denmark)

    Schultz, Alexander; Boye, Birgitte; Jonsson, Olof;

    2015-01-01

    complications, loss of kidney function and hospital stay, in these patients. Material and methods. This prospective study included 52 consecutive patients (nine men and 43 women) with various benign disorders. Twenty-six patients received an ileal conduit and 26 a continent cutaneous diversion. The patients...... improvement between patients with continent and those with incontinent diversion. Mean hospital stay was 14 days. Early and late complications required open surgery in 12 patients (23%). GFR was unchanged postoperatively. Conclusions.Urinary diversion improves health-related and disease-specific quality of......Abstract Objective.Urinary diversion may be an option in patients with disabling lower urinary tract dysfunction (DLUTD), refractory to conservative and minor invasive treatment. The aim of this study was to evaluate whether urostomy improves quality of life and cost of surgery, in terms of...

  3. Measuring Health-Related Quality of Life of Adults With Down Syndrome.

    Science.gov (United States)

    Graves, Rebecca Jermyn; Graff, J Carolyn; Esbensen, Anna J; Hathaway, Donna K; Wan, Jim Y; Wicks, Mona Newsome

    2016-07-01

    This study examined self- and caregiver-reported health-related quality of life (HRQOL) of 60 adults with Down syndrome (DS) using the QualityMetric Short Form-12 version 2 (SF-12v2). All HRQOL scores exceeded means and fell within one standard deviation of the SF-12v2 normative sample. Similarities between eight self- and caregiver-reported HRQOL scales were found with the exception of role physical scores (impact of health problems on typical accomplishments), which were lower when obtained by caregiver-report. A positive association was found between self- and caregiver-reported physical functioning scores (impact of health problems on physical activity). The SF-12v2 had high construct validity in this study. These findings support the feasibility of measuring HRQOL of adults with DS using self-report rather than reliance on caregiver-report. PMID:27351699

  4. Health-related quality of life in long-term survivors of childhood brain tumors

    DEFF Research Database (Denmark)

    Reimers, Tonny Solveig; Mortensen, Erik Lykke; Nysom, Karsten; Schmiegelow, Kjeld

    2009-01-01

    -up were assessed for general intelligence (IQ) and administered the Minneapolis-Manchester Quality of Life (MMQL) questionnaire. RESULTS: In multivariate linear regression treatment with RT was the most important risk factor for reduced HRQOL. Lower scores for physical functioning and energy, social......BACKGROUND: To identify predictors for health-related quality of life (HRQOL) in survivors of childhood brain tumors and its relationship to cognitive function. PROCEDURE: One hundred twenty-six consecutive Danish childhood brain tumor patients treated 1970-1997 and being 7.9-40.4 years at follow...... functioning, cognitive functioning, body image, outlook of life, and intimate relations were significantly related to RT. Tumor location in the posterior fossa was associated with lower scores for physical functioning and energy, and tumor site in the third ventricle region was associated with lower scores...

  5. Health-related quality of life after prolonged pediatric intensive care unit stay.

    LENUS (Irish Health Repository)

    Conlon, Niamh P

    2012-02-01

    OBJECTIVE: To investigate the long-term health-related quality of life (HRQOL) outcomes for patients requiring at least 28 days of pediatric intensive care. DESIGN: Retrospective cohort and prospective follow-up study. SETTING: A 21-bed pediatric intensive care unit (PICU) in a university-affiliated, tertiary referral pediatric hospital. PATIENTS: One hundred ninety-three patients who spent 28 days or longer in the PICU between January 1, 1997 and December 31, 2004. INTERVENTIONS: Quality of life was measured using the Pediatric Quality of Life Inventory (Peds QL 4.0) parent-proxy version at 2 to 10 yrs after discharge. The PedsQL 4.0 is a modular measure of HRQOL, which is reliable in children aged 2 to 18 yrs. It generates a total score and physical, emotional, social, school, and psychosocial subscores. MEASUREMENTS AND MAIN RESULTS: Of the 193 patients, 41 died during their PICU admission and 27 died between PICU discharge and follow-up. Quality of life questionnaires were posted to parents of 108 of the 125 survivors and 70 were returned completed. Forty children (57.1%) had scores indicating a normal quality of life, whereas 30 (42.9%) had scores indicating impaired HRQOL. Of these, 14 (20%) had scores indicating poor quality of life with ongoing disabling health problems requiring hospitalization or the equivalent. CONCLUSIONS: Our results indicate that, while long PICU stay is associated with significant mortality, the long-term HRQOL is normal for the majority of surviving children.

  6. Health-related quality of life (Hr-Qol in patients with type 2 diabetes mellitus

    Directory of Open Access Journals (Sweden)

    Vishakha Jain

    2014-01-01

    Full Text Available Background: Quality of life is an important aspect in diabetes because poor quality of life leads to diminished self-care, which in turn leads to worsened glycemic control, increased risks for complications, and exacerbation of diabetes overwhelming in both the short run and the long run. Aims: The aim of our study is to examine the health-related quality of life of diabetic patients in rural India. Materials and Methods: This case-control study was done among type 2 diabetes mellitus patients attending Medicine Outpatient department of a 780-bedded rural medical college located in central India. We used the World Health Organization Quality of Life Questionnaire - short version (WHOQOL-BREF to assess quality of life. Results: The HRQOL among diabetics and non-diabetic controls is comparable to each other with bad physical health, bad psychological health, deteriorating social relationships, and bad environmental conditions affecting the HRQOL of both the groups equally. The overall HRQOL of the total study population (cases and controls was poor. Conclusion: The finding of this study will help in health promotion in rural medical practice in India. It would beckon the much awaited avenue of holistic care of a diabetic patient with equal importance to the mental wellbeing and quality of life, as compared to physical well being.

  7. Evaluating the impact of wind turbine noise on health-related quality of life

    Directory of Open Access Journals (Sweden)

    Daniel Shepherd

    2011-01-01

    Full Text Available We report a cross-sectional study comparing the health-related quality of life (HRQOL of individuals residing in the proximity of a wind farm to those residing in a demographically matched area sufficiently displaced from wind turbines. The study employed a nonequivalent comparison group posttest-only design. Self-administered questionnaires, which included the brief version of the World Health Organization quality of life scale, were delivered to residents in two adjacent areas in semirural New Zealand. Participants were also asked to identify annoying noises, indicate their degree of noise sensitivity, and rate amenity. Statistically significant differences were noted in some HRQOL domain scores, with residents living within 2 km of a turbine installation reporting lower overall quality of life, physical quality of life, and environmental quality of life. Those exposed to turbine noise also reported significantly lower sleep quality, and rated their environment as less restful. Our data suggest that wind farm noise can negatively impact facets of HRQOL.

  8. Dental health and oral health-related quality of life in children with congenital bleeding disorders.

    Science.gov (United States)

    Salem, K; Eshghi, P

    2013-01-01

    The purpose of this study was to investigate the dental and some other aspects of oral health status of young patients with congenital bleeding disorders (CBD) and the impact of these on their quality of life (OHR-QoL) compared with controls. DMFS-dmfs (Decayed, Missed, Filled Tooth surfaces in permanent and primary teeth) scores, Simplified oral hygiene index, occurance of hypoplasia of first permanent molars, Temporomandibular joint dysfunction and occlusion of 46 CBD patients at the age range of 2-15 years and 46 of other children as control were compared, and the impact of their oral health situation on quality of life was also investigated. Data were analysed by chi-square, t-test and Pearson correlation. Patients were significantly more caries-free with less decayed teeth in primary-permanent dentition (P = 0.03, t = -2.17).The mean scores of OHR-QoL of CBD patients and controls were not significantly different. Oral Bleeding was the significant variable in relation to 'oral health-related quality of life' in CBD groups (Pearson correlation, r = -0.56, P = 0.000). OHR-QoL in the control group was related to dmfs score (r = -0.392, P = 0.011) and male gender (r = -0.329, P = 0.026). Congenital bleeding disorder CBD patients were found to have a better dental health situation in primary dentition compared with controls; however, their 'oral health-related quality of life' was similar. Oral bleeding was the only significant factor related to OHR-QoL in CBD. It shows an overall importance of development of comprehensive care centres for CBD as the main cause of this achievement. PMID:22970656

  9. The impact of burning mouth syndrome on health-related quality of life

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    Silva Tarcília A

    2011-07-01

    Full Text Available Abstract Background Burning mouth syndrome is a chronic disorder that is characterized by a burning sensation and a normal clinical appearance of the oral mucosa. This condition often affects the health-related quality of life in patients. As such, the aim of this study was to compare the health-related quality of life of patients with BMS and healthy controls, using the validated Portuguese versions of the SF-36 and OHIP-49 questionnaires. Methods A calculated sample of Brazilian patients with BMS (n = 26 was compared with a control group (n = 27, paired for gender and age. Sociodemographic information and clinical characteristics were obtained, and interviews were conducted using the SF-36 and OHIP-49. To evaluate the normality of the variables, we used the Kolmogorov-Smirnov test. The chi-square test, Fisher exact test and Mann-Whitney U-Test were used to compare sociodemographic and clinical characteristics of individuals with BMS and controls Mann-Whitney U-test were carried out to compare SF-36 and OHIP-49 between BMS patients and controls. The significance level was set at 0.05. To compare the dimensions of the SF-36 and OHIP-49 between BMS patients and controls, we considered Bonferroni correction. So for comparison of the dimensions, the significance level was set at 0.00625 for SF-36 and at 0.00714 for OHIP-49. Results The clinical and demographic data were similar in both groups (P > 0.05. SF-36 scores were significantly lower in all domains for patients with BMS (P Conclusions BMS has a negative impact on the health-related quality of life of individuals, as can be shown by instruments such as the SF-36 and OHIP-49. So, the evaluation of quality of life might be useful for more information about the nature and severity of BMS, to evaluate the effects of treatment protocols, in order to improve their outcomes by means a humanized clinical practice.

  10. Relationship between asthma control, health-related quality of life and subjective well-being in Czech adults with asthma

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    Elena Gurková

    2015-09-01

    Full Text Available Aims: To investigate the relationship between asthma control, health related quality of life and subjective well-being in Czech adult patients with asthma. Design: A prospective observational cohort study. Methods: The sample included 316 people with asthma. In this 12-month observational study, patients were tested three times - at the baseline and after six and 12 months. Asthma control, health related quality of life and subjective well-being were assessed at the initial time point and followed up at six and 12 months by using the Asthma Control Test, the Mini Asthma Quality of Life Questionnaire and the Personal Well-being Index. Results: Level of asthma control and health related quality of life improved during the 12-month period, although spirometric parameters and subjective well-being were without significant change. Asthma control remained a significant predictor of health-related quality of life and general subjective well-being in linear regression models. Conclusions: Health-related quality of life is a construct based on a larger set of clinical variables when compared to subjective well-being. The regular monitoring of asthma control is associated with increased awareness and therapeutic expectations in patients, and better asthma control and health-related quality of life.

  11. Health-related quality of life and health condition of community-dwelling populations with cancer, stroke, and cardiovascular disease.

    Science.gov (United States)

    Hong, Eunkyoung

    2015-08-01

    [Purpose] The purpose of this study was to investigate health conditions and HRQoL (health-related quality of life) of community-dwelling populations with cancer, stroke, and CVD (cardiovascular disease) based on standardized data. [Subjects] The study subjects numbered 422 in total: 179 patients had cancer, 128 were stroke patients, and 115 were CVD patients. [Methods] This study used data collected during health interviews carried out as part of the sixth Korean National Health and Nutrition Examination Survey. Face-to-face health interviews were conducted by trained surveyors who visited households during 2013. The contents of the interviews included data on demographic factors, physical condition, psychological condition, and HRQoL. [Results] Stress perceptions related to health condition differed significantly across the populations of cancer, stroke, and CVD patients. The HRQoL items of mobility, self-care, usual activities, and anxiety/depression also differed significantly across these populations. [Conclusion] Healthcare teams will now be in a position to plan programs for improvement in these areas according to the features of each disease. PMID:26355816

  12. Measuring the effect of intimate partner violence on health-related quality of life: a qualitative focus group study

    OpenAIRE

    Thomas Kristie A; Joshi Manisha; Wittenberg Eve; McCloskey Laura A

    2007-01-01

    Abstract Background Health related quality of life (HRQOL) can be measured by a wide range of instruments, many of which have been designed for specific conditions or uses. "Preference-based" measures assess the value individuals place on health, and are included in economic evaluations of treatments and interventions (such as cost effectiveness analysis). As economic evaluation becomes more common, it is important to assess the applicability of preference-based health related quality of life...

  13. Impact of exercise capacity on dyspnea and health-related quality of life in patients with chronic obstructive pulmonary disease

    DEFF Research Database (Denmark)

    Jacobsen, Ramune; Frølich, Anne; Godtfredsen, Nina S

    2012-01-01

    To assess the impact of the amount of exercise training during pulmonary rehabilitation (PR) program for improvements in dyspnea and health-related quality of life (HRQOL) in patients with chronic obstructive pulmonary disease (COPD).......To assess the impact of the amount of exercise training during pulmonary rehabilitation (PR) program for improvements in dyspnea and health-related quality of life (HRQOL) in patients with chronic obstructive pulmonary disease (COPD)....

  14. The practical impact of differential item functioning analyses in a health-related quality of life instrument

    DEFF Research Database (Denmark)

    Scott, Neil W; Fayers, Peter M; Aaronson, Neil K;

    2009-01-01

    Differential item functioning (DIF) analyses are commonly used to evaluate health-related quality of life (HRQoL) instruments. There is, however, a lack of consensus as to how to assess the practical impact of statistically significant DIF results.......Differential item functioning (DIF) analyses are commonly used to evaluate health-related quality of life (HRQoL) instruments. There is, however, a lack of consensus as to how to assess the practical impact of statistically significant DIF results....

  15. Health related quality of life measure in systemic pediatric rheumatic diseases and its translation to different languages: an international collaboration

    OpenAIRE

    Moorthy, Lakshmi Nandini; Roy, Elizabeth; Kurra, Vamsi; Peterson, Margaret GE; Hassett, Afton L.; Lehman, Thomas JA; ,; Scott, Christiaan; El-Ghoneimy, Dalia; Saad, Shereen; El Feky, Reem; Al-Mayouf, Sulaiman; Dolezalova, Pavla; Malcova, Hana; Herlin, Troels

    2014-01-01

    Background Rheumatic diseases in children are associated with significant morbidity and poor health-related quality of life (HRQOL). There is no health-related quality of life (HRQOL) scale available specifically for children with less common rheumatic diseases. These diseases share several features with systemic lupus erythematosus (SLE) such as their chronic episodic nature, multi-systemic involvement, and the need for immunosuppressive medications. HRQOL scale developed for pediatric SLE w...

  16. Iranian version of modified polycystic ovary syndrome health-related quality of Life questionnaire: Discriminant and convergent validity

    OpenAIRE

    Fatemeh Bazarganipour; Saeide Ziaei; Ali Montazeri; Fatemeh Foroozanfard; Soghrat Faghihzadeh

    2013-01-01

    Background: A preliminary report indicated that the Iranian version of modified polycystic ovary syndrome health-related quality of life questionnaire (MPCOSQ) is a valid measure of health-related quality of life (HRQOL) in PCOS patients. Accordingly, the Iranian version of MPCOSQ was subjected to further psychometric analyses among a different sample of patients with PCOS. Objective: To examine discriminant and convergent validity of the Iranian version of MPCOSQ. Materials and Methods: This...

  17. Health-Related Quality of Life of Nigerian Children with Cerebral Palsy

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    A E Ogunrinu

    2011-10-01

    Full Text Available Purpose: To assess the impact of cerebral palsy on health-related quality of life (HRQoL of Nigerian children.Method: This is a cross-sectional survey. The study involved 54 children (33 males and 21 females, between 1 and 12 years of age, with cerebral palsy. They were consecutively recruited from two tertiary health institutions in Lagos, Nigeria. The socio-demographic details of the participants were obtained through interviews. Their HRQoL was assessed using the Child Health Questionnaire-Parent Form-28 (CHQ-PF 28. The questionnaire was completed by their parents, guardians or primary care-givers. Severity of motor disability was assessed and classified using the Gross Motor Function Classification System (GMFCS. Data were summarised using descriptive statistics. Chi-square was used to find the association between each of the selected socio-demographic variables and motor disability, and HRQoL.Results: Thirty-eight children (70.3% were between 1 and 6 years of age, and 16 (29.7% were between 7 and 12 years. The participants’ overall scores and scores on each domain of CHQ-PF 28 were very low. Majority (69.5% were in GMFCS classification-level 1, 7 (13.0% were in level 2, 12 (22.2% were in level 3, 14 (25.9% were in level 4, and 16 (29.6% were in level 5. Age had significant effect (CI = 95% on HRQoL of children with cerebral palsy. Severity of disability had negative impact (CI = 95% on HRQoL of children with cerebral palsy. Conclusions: The health-related quality of life of Nigerian children with cerebral palsy is low, and is negatively affected by age and severity of disability. Key words: Quality of life, cerebral palsy, children, Nigeriadoi 10.5463/DCID.v22i2.24

  18. Health-Related Quality of Life in Primary Immune Deficient Patients

    Directory of Open Access Journals (Sweden)

    "Habibeh Mozaffari

    2006-03-01

    Full Text Available The primary immunodeficiency (PI disorders are abnormalities in development and maturation of the immune system. Individuals with PI disease may experience frequent infections, which limit their abilities to exhibit physical and psychological well-being secondary to their illness. In this survey we compared health-related quality of life of primary immune deficient patients with healthy children. The case-control study was designed for patients with PI disease who were referred to Children Medical Center in 2004-2005. Demographic information was taken and Pediatric Quality Of Life (PEDQOL questionnaire were filled for 50 PI patients and 100 healthy children. The mean age in PI patients was 12.62± 3.65 (range from 8 to 18 years and in the control group was 11.04± 3.3 years. In PI patients 68% were male and 32% female .Most patients with PI disease had a diagnosis of common variable immunodeficiency (54% or X-linked agammaglobulinemia (24%. Patients with PI disease had great limitations in physical functioning and psychological well-being (p<0.001 and p<0.001 respectively compared with children without a chronic health condition. Patients had lower PEDQOL scores in all age groups compared with normal sample (p<0.001. Long duration of disease significantly correlated with low psychological score. (r = -3.23. P= 0.03 Children with PI disease experience poorer health related quality of life than healthy children, indicating more attention should be paid to early diagnosis and treatment of PI disease, as well as more attention to their social limitation. PI patients may need psychological consultation for better coping with their illness.

  19. The impact of xerostomia on oral-health-related quality of life among younger adults

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    Broadbent Jonathan M

    2006-11-01

    Full Text Available Abstract Background Recent research has suggested that chronic dry mouth affects the day-to-day lives of older people living in institutions. The condition has usually been considered to be a feature of old age, but recent work by our team produced the somewhat surprising finding that 10% of people in their early thirties are affected. This raises the issue of whether dry mouth is a trivial condition or a more substantial threat to quality of life among younger people. The objective of this study was to examine the association between xerostomia and oral-health-related quality of life among young adults while controlling for clinical oral health status and other potential confounding factors. Methods Cross-sectional analysis of data from a longstanding prospective observational study of a Dunedin (New Zealand birth cohort: clinical dental examinations and questionnaires were used at age 32. The main measures were xerostomia (the subjective feeling of dry mouth, measured with a single question and oral-health-related quality of life (OHRQoL measured using the short-form Oral Health Impact Profile (OHIP-14. Results Of the 923 participants (48.9% female, one in ten were categorised as 'xerostomic', with no apparent gender difference. There was a strong association between xerostomia and OHRQoL (across all OHIP-14 domains which persisted after multivariate analysis to control for clinical characteristics, gender, smoking status and personality characteristics (negative emotionality and positive emotionality. Conclusion Xerostomia is not a trivial condition; it appears to have marked and consistent effects on sufferers' day-to-day lives.

  20. Gender differences in health related quality of life of young heroin users

    Directory of Open Access Journals (Sweden)

    González-Saiz Francisco

    2010-12-01

    Full Text Available Abstract Background Health Related Quality of Life (HRQL of opiate users has been studied in treatment settings, where assistance for drug use was sought. In this study we ascertain factors related to HRQL of young opiate users recruited outside treatment facilities, considering both genders separately. Methods Current opiate users (18-30 y were recruited in outdoor settings in three Spanish cities (Barcelona, Madrid, Sevilla. Standardised laptop interviews included socio-demographic data, drug use patterns, health related issues, the Severity of Dependence Scale (SDS and the Nottingham Health Profile (NHP. Results A total of 991 subjects (73% males, mean age = 25.7 years were interviewed. The mean global NHP score differed by gender (women: 41.2 (sd:23.8; men:34.1(sd:23.6;p Conclusions Heroin users were found to be at a considerable risk of impaired HRQL, even in these young ages. A score approaching severity of dependence was the factor with the strongest relation with it.

  1. Health-related restrictions of choices and choosing: implications for quality of life and clinical interventions

    Directory of Open Access Journals (Sweden)

    Barry J Gurland

    2010-08-01

    Full Text Available Barry J Gurland1, Huai Cheng2, Mathew S Maurer31Columbia University Department of Psychiatry, Stroud Center for Study of Quality of Life, New York, NY, USA; 2Anderson Cancer Center, Houston, TX, USA; 3Columbia Presbyterian Medical Center, New York, NY, USABackground: The process of “accessing choices and choosing among them” (c-c has been proposed as a model for understanding, evaluating, and assisting a patient’s management of quality of life. If desired choices are freely accessible, and the act of choosing is efficient and unconstrained, then the outcome is optimized quality of life. The c-c model fits many clinical situations where improved quality of life is a goal, and interventions may be aimed at relieving health-related restrictions of the patient’s desired activities. Aims: To determine the impact of health restrictions of choices and choosing on indicators and outcomes reflecting quality of life. Method: Secondary analysis of a community-based health survey of three ethnic groups, 65 years and older (n = 2,130, repeated after 18 months, with mortality over 6 years. Findings: Complaints of health restrictions of desired activities accounted for about half the variance of all determinants of a quality of life proxy indicator, and had a high frequency. Such complaints also predicted declines in mood and function, higher death rates, and increased service use.Conclusions: Clinical trials are warranted of the efficacy for quality of life improvement of interventions that focus on the relief of health-induced restrictions of desired activities.Keywords: choice, quality of life, aging, health restrictions

  2. Overall mental distress and health-related quality of life after solid-organ transplantation: results from a retrospective follow-up study

    Directory of Open Access Journals (Sweden)

    Baranyi Andreas

    2013-02-01

    Full Text Available Abstract Background Our retrospective follow-up study aimed to explore the degree of overall mental distress in a cohort of solid-organ transplantation (SOT recipients after liver, heart or lung transplantation. Furthermore, we investigated how overall mental distress is linked to health-related quality of life. Methods 123 SOT patients treated during the study period were enrolled in this investigation at a mean of 24.6 months (SD=11.6 after transplantation. Before transplantation, the Transplant Evaluation Rating Scale (TERS was used to classify the level of adjustment in psychosocial functioning among transplantation candidates. After transplantation, recipients completed a research battery, which included the SCL-90-R, and the SF-36. Results 39 (31.7% transplantation recipients had clinically significant overall mental distress as measured on the Global Severity Index of the SCL-90-R. Obsessive-compulsive symptoms (92.3%, somatization symptoms (87.2%, anxiety symptoms (84.6%, depression symptoms (82.1% and phobic anxiety symptoms (69.2% were a frequent finding. Transplantation recipients with overall mental distress had significant lower levels of adjustment in psychosocial functioning before transaplantation than those without overall mental distress as measured in the TERS. Transplantation-related overall mental distress symptomatology was associated with maximal decrements in health-related quality of life. Conclusion Transplantation recipients may face major transplantation- and treatment-related overall mental distress and impairments to their health-related quality of life. Further, overall mental distress is a high-risk factor in intensifying impairments to patients’ overall quality of life.

  3. Health-related quality of life in sporadic adult-onset ataxia.

    Science.gov (United States)

    Abele, Michael; Klockgether, Thomas

    2007-02-15

    Despite progressive disability in sporadic adult-onset ataxia (SAOA), little is known about patients' assessment of their ataxic disorder and its impact on health-related quality of life (Hr-QoL). This study investigated Hr-QoL by means of the following self-administered scales: Pittsburgh Sleep Quality Index, Epworth Sleepiness Scale, Beck Depression Inventory (BDI), and the Medical Outcome Study Short Form (SF-36). Twenty-two unselected ataxia patients were included. Sleep-related complaints were found in 9 (41%) of 22 and symptoms of depression in 6 (38%) of 16 patients. Compared to a large german control group, SAOA patients had lower scores in all SF-36 dimensions except for bodily pain. The greatest impairment was found in the domain physical functioning, followed by the domains social functioning and role limitations (emotional problems). There was a significant negative correlation of all nonmotor SF-36 dimensions with the BDI score. Walking aid dependency was significantly correlated with poorer health status perception in several motor and nonmotor domains. In addition, impaired sleep quality was correlated with an impaired general health perception and with bodily pain. The study demonstrates a great impact of SAOA on Hr-QoL. Adequate treatment of depression, motor disability, and impaired sleep quality is essential to improve Hr-QoL in ataxic patients. PMID:17149704

  4. Health-related quality of life in Guillain-Barré syndrome patients: a systematic review.

    Science.gov (United States)

    Darweesh, Sirwan K L; Polinder, Suzanne; Mulder, Maxim J H L; Baena, Cristina P; van Leeuwen, Nikki; Franco, Oscar H; Jacobs, Bart C; van Doorn, Pieter A

    2014-03-01

    Guillain-Barré syndrome (GBS) encompasses a broad spectrum of health-related quality of life (HRQL) determinants, including mobility, fatigue, pain, and depression. We systematically reviewed the literature on functional outcome domains in which GBS patients experience limitations in the short and long terms and evaluated determinants of HRQL in GBS patients. MEDLINE and EMBASE were systematically searched by two independent reviewers for articles covering HRQL data of GBS patients. Of 730 abstracts screened, 17 articles covering data of 14 studies matched the selection criteria. The included articles showed that many GBS patients experienced physical limitations, even years after the acute phase of the disease, while results were inconsistent for perceived levels of pain, fatigue, and general mental well-being. Only three papers covered HRQL assessments at more than one time point, generally showing large improvements in HRQL in the first year after GBS onset, but not thereafter. We appraised the methodological quality of included studies using a 13-item checklist; none of the articles fulfilled all items and only seven articles presented data on correlations between HRQL and determinants. In conclusion, the majority of studies on HRQL in GBS patients are cross-sectional and of low methodological quality. This paper provides guidance for much needed high-quality studies on patterns of patient-perceived recovery after GBS onset. PMID:24456426

  5. Health-Related Quality of Life after Cystectomy and Urinary Diversion for Bladder Cancer

    Directory of Open Access Journals (Sweden)

    Cheryl Shih

    2011-01-01

    Full Text Available With multiple options for urinary diversion after radical cystectomy for bladder cancer that have comparable cancer control and complication rates, health-related quality of life (HRQOL has become an important consideration. This article reviews the methods for defining HRQOL, the challenges in measuring HRQOL in bladder cancer, and the literature comparing HRQOL after various methods of urinary diversion. Recent contributions include the validation of HRQOL instruments specific to bladder cancer and the publication of several prospective studies measuring HRQOL outcomes after cystectomy and urinary diversion. There is no convincing evidence from existing literature that any particular method of urinary diversion offers superior HRQOL outcomes. Rather, there is growing evidence that good HRQOL can be achieved with patient education and consideration of each patient's clinical and psychosocial situation. Future research should utilize the validated bladder cancer specific HRQOL instruments and perhaps explore the impact of preoperative counseling on postoperative HRQOL.

  6. Improvement in health-related quality of life following Roux-en-Y gastric bypass

    DEFF Research Database (Denmark)

    Hansen, Nina Beck; Gudex, Claire; Støving, René Klinkby

    2014-01-01

    INTRODUCTION: This study explored whether health-related quality of life (HRQOL) changes following Roux-en-Y gastric bypass surgery were associated with identifiable socio-demographic or clinical characteristics, and it examined the impact on health outcomes of changes in the Danish criteria for...... bariatric surgery. MATERIAL AND METHODS: Participants (n = 55) completed the Short Form Health Survey v2 (SF-36) before and 22 ± 4.2 months after surgery. Information on socio-demographics, body mass index (BMI), co-morbidity and satisfaction with surgery were collected through patient questionnaires and...... hospital records. RESULTS: There was overall improvement on all SF-36 subscales and in the mean physical score (PCS) and mean mental score (MCS) (p = 0.001). A total of five patients had lower PCS and 13 patients had lower MCS after surgery, but we identified no particular characteristics associated with...

  7. Health-related quality of life in Iranian patients with multiple sclerosis

    DEFF Research Database (Denmark)

    Pakpour, Amir H.; Yekaninejad, Mir Saeed; Mohammadi, Nastaran Keshavarz;

    2009-01-01

    Background and purpose: This study aimed to evaluate aspects of health-related quality of life (HRQoL) of patients with multiple sclerosis (MS) who live in Tehran and to compare data with evaluations of both the general population and MS patients in other countries Material and methods: One hundred...... and forty patients with MS, yet without severe comorbidity, were selected according to convenience in a cross-sectional study. Data were collected by means of the SF-36 questionnaire and Beck Depression Inventory (BDI). The Expanded Disability Status Scale of Kurtzke (EDSS) and Mini Mental State...... all of the SF-36 scales. Moreover, the BDI and EDSS were found to be positively correlated with one another (r = 0.415, p < 0.01)....

  8. Oral health-related quality of life and complications after treatment with partial removable dental prosthesis

    DEFF Research Database (Denmark)

    Al-Imam, H; Özhayat, E B; Benetti, A R;

    2016-01-01

    The aims of this study were to measure and describe the oral health-related quality of life (OHRQoL) and to identify the complications caused by partial removable dental prosthesis (RDPs) in patients 1-5 years after treatment. Complications were identified in 65 patients who were treated with 83...... and 4. A significant improvement (P < 0·05) in the total OHIP-49 was registered from pre-treatment (mean 42, SD ± 37) to baseline (mean 29, SD ± 27) and from pre-treatment to 1-5 years after treatment (mean 32, SD ± 30). There was no significant difference between the baseline and 1- to 5-year follow...

  9. [Health-related quality of life (SF-36) in chronic low back pain and comorbid depression].

    Science.gov (United States)

    Ahrens, C; Schiltenwolf, M; Wang, H

    2010-06-01

    The purpose is to clarify if comorbidity of depression reduces health-related quality of life (SF-36) in patients with chronic low back pain (CR) and if those comorbid patients (CR+DE) benefit from multimodal pain treatment. Two groups (CR and CR+DE) each with 29 patients are compared over 6 months on study days 0, 21 (inpatient) and 180 (outpatient). Differences exist only at days 0 and 21, not at day 180, with group CR exhibiting higher SF-36 values in each case. Group CR+DE improves in the inpatient phase and especially in the outpatient phase and therefore over the entire study period more than group CR which increases solely in the inpatient phase. The comorbid group is more severely affected by their illness, but improves very constantly. The outpatient improvement suggests a good long-term prognosis. PMID:20458502

  10. Childhood bruxism: Related factors and impact on oral health-related quality of life.

    Science.gov (United States)

    Antunes, Lívia Azeredo Alves; Castilho, Thuanny; Marinho, Marcello; Fraga, Renato Silva; Antunes, Leonardo Santos

    2016-01-01

    This study aimed to assess childhood bruxism relating associated factors and the bruxism's impact on oral health-related quality of life (OHRQoL). A case-control study was performed with 3- to 6-year-old children obtained from public preschools in Brazil. The case and control groups had 21 and 40 children, respectively. Associations between bruxism and respiratory problems (p = 0.04, OR: 0.33, CI: 0.09 to 1.14), dental wear (p 0.05). The association between presence and absence of impact with bruxism or other variables showed no statistical relationship (p > 0.05). It could be concluded that childhood bruxism is related to respiratory problems, dental wear, dental caries, and malocclusion. Despite being a topic that demands special care in dentistry, bruxism does not significantly affect the OHRQoL. PMID:26388123

  11. [Role of health-related quality of life in clinical practice: subjectivity in evidence].

    Science.gov (United States)

    Martí, Camelia; Santos, Alicia; Ybarra, Juan; Martínez, María Antonia; Resmini, Eugenia; Roig, Olga; Webb, Susan M; José Barahona, M

    2009-01-01

    The incorporation of subjective elements provided by the patient to medical practice constitutes a new bridge between two historical movements of human culture: naturalism and rationalism. In recent years, medical sciences have identified these movements as patient-centered medicine and evidence-based medicine. By revisiting the paradigms of medicine, theories of causality, doctor-patient relationship models, bioethical principles and examples of clinical studies, their role and meaning has been revised. The applicability for neuroendocrinology has been demonstrated by validating therapeutic results with measurement of health-related quality of life. The need to incorporate the patient's subjective perception poses a challenge that, when accepted, can advance the understanding and care of human beings--ultimately rational, thinking subjects, and therefore subjective--as our species has been defined. PMID:19695514

  12. Centella asiatica Improves Physical Performance and Health-Related Quality of Life in Healthy Elderly Volunteer

    Directory of Open Access Journals (Sweden)

    Lugkana Mato

    2011-01-01

    Full Text Available Recently, oxidative stress has been reported to contribute an important role in the decline of physical function as age advances. Numerous antioxidants can improve both physical and psychological performances resulting in the increase of health-related quality of life (HQOL. Therefore, we hypothesized that Centella asiatica, a medicinal plant reputed for nerve tonic, strength improvement and antioxidant activity, could improve the physical performance and HQOL especially in the physical satisfaction aspect, of the healthy elderly volunteer. To test this hypothesis, a double-blind, placebo-controlled, randomized trial was performed. Eighty healthy elderly were randomly assigned to receive placebo or standardized extract of C. asiatica at doses of 250, 500 and 750 mg once daily for 90 days. The subjects were evaluated to establish baseline data of physical performance using 30-s chair stand test, hand grip test and 6-min walk test. The health-related quality of life was assessed using SF-36. These assessments were repeated every month throughout the 3-month experimental period using the aforementioned parameters. Moreover, 1 month after the cessation of C. asiatica treatment, all subjects were also evaluated using these parameters again. The results showed that after 2 months of treatment, C. asiatica at doses of 500 and 750 mg per day increased lower extremity strength assessed via the 30-s chair stand test. In addition, the higher doses of C. asiatica could improve the life satisfaction subscale within the physical function subscale. Therefore, the results from this study appear to support the traditional reputation of C. asiatica on strength improvement, especially in the lower extremities of the elderly. C. asiatica also possesses the potential to be a natural resource for vigor and strength increase, in healthy elderly persons. However, further research is essential.

  13. Health-related quality of life in men receiving prostate brachytherapy on RTOG 98-05

    International Nuclear Information System (INIS)

    Purpose: To prospectively assess health-related quality of life (HRQOL) during the first year after treatment with prostate brachytherapy (PB) alone for T1c-2a prostate cancer. Materials and Methods: Ninety-eight patients from 24 institutions were eligible and properly entered on this study. All patients were treated with PB alone using I-125 (Oncura Model 6711). The prescription dose was 145 Gy. Three separate health-related quality of life questionnaires (HRQOL) (Functional Assessment of Cancer Therapy-Prostate [FACT-P], Sexual Adjustment Questionnaire [SAQ], and International Prostate Symptom Score [IPSS]) were self-administered before and after PB (baseline; 3, 6, 9, and 12 months after PB). The standard error of the mean (SEM) was used to analyze changes in HRQOL scores over time. Patients who improved greater than the SEM were categorized as improved; patients that declined greater than the SEM were categorized as declined; patients were otherwise categorized as stable. All changes are measured using the pretreatment HRQOL score as baseline. Results: The percentage of men who reported the ability to have an erection decreased from 73% at baseline (65% unassisted, 8% assisted) to 57% at 1 year (36% unassisted, 21% assisted). The rate of urinary incontinence increased to 14% at 6 months but had decreased to 1% at the 12-month follow-up. At 1 year after PB, 80% of men reported decreased sexual functioning according to SAQ scores. More than 60% of men reported decreased urinary function at 12 months compared with baseline. Conclusions: This article represents the first prospective, multi-institutional study of HRQOL in men treated with PB and demonstrates that patients undergoing PB have a very high overall HRQOL. The rate of incontinence by 1 year after PB is low, but many patients continue to have obstructive symptoms at 1 year. Although 78% of 1-year respondents state that they can achieve an erection with or without assistance, almost 50% report a decrease in

  14. Medical students` health-related quality of life - a comparative study

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    Latas Milan

    2014-01-01

    Full Text Available Background/Aim. Previous studies on medical students’ subjective perception of health and health-related quality of life (HRQoL showed inconclusive results. Moreover, there are no published studies to compare HRQoL of medical students to non-medical university students. The aim of the study was to assess subjective perception of health-related quality of life (HRQoL in medical students’ sample, to compare it with non-medical university stu-dents and to ascertain predictors of better perception of HRQoL in medical students. Methods. Scores of all domains on the Mental and Physical Component Summary subscales and total score of the Short Form Health Survey (SF-36, used for assessment of HRQoL in samples of 561 medical and 332 non-medical university students were assessed and compared. In addition, linear regression to identify predictors of better perception of mental and physical components of HRQoL and overall HRQoL in the sample of medical students was used. The dependant variables were subscores and total score with the SF- 36, and independent variables were certain sociodemographic and academic characteristics of the students. Results. Medical students had statistically significantly higher scores on the Mental Component Summary and total SF-36 score compared to non-medical students. Linear regression analysis demonstrated that higher scores of Physical Component Summary were associated with age, male sex and the year of studies. The Mental Component Summary were associated with age, male sex, the year of studies and marital status. The total SF-36 score was associated with age, male sex and the year of studies. Conclusion. Medical students perceive their health much better than other university students do, but female, older and second grade medical students have worse perception of their HRQoL. Those points should be potential target areas for specific prevention and treatment in order to achieve better HRQoL.

  15. An Assessment of Health Related Quality of Life in a Male Prison Population in Greece Associations with Health Related Characteristics and Characteristics of Detention

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    Constantinos Togas

    2014-01-01

    Full Text Available Background. Prisoners constitute a group with increased health and social care needs. Although implementing policies that aim at improving outcomes within this population should be a priority area, studies that attempt to assess health outcomes and health related quality of life (HRQoL in this population are limited. Aim. To assess HRQoL in a prison population in Greece and to explore the relationship between HRQoL and a set of individual sociodemographic and health related characteristics and characteristics of detention. Methods. A cross-sectional study involving 100 male prisoners was conducted in the prison of Corinth in Greece. HRQoL was assessed through the use of the SF-36 and the EQ-5D. Results. The mean physical and mental summary scores of the SF-36 were 55.33 and 46.82, respectively. The EQ-VAS mean score was 76.41%, while the EQ-5D index was 0.72. Multivariate analysis identified a statistical relationship between HRQoL and the conditions of detention, controlling for the effect of sociodemographic characteristics, morbidity, and mental problems. The use of narcotics in particular is significantly associated with lower HRQoL. Conclusions. Implementation of policies that aim at preventing the use of narcotics within the prison environment is expected to contribute to improved HRQoL in this population.

  16. Self-reported psychopathology and health-related quality of life in heroin users treated with methadone

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    Chen YZ

    2012-12-01

    Full Text Available Ying-Zai Chen,1 Wei-Lieh Huang,1,2,5 Jia-Chi Shan,4,5 Yu-Hsuan Lin,1–3,5 Hung-Chieh Wu Chang,1 Li-Ren Chang1,61Department of Psychiatry, National Taiwan University Hospital, Yun-Lin Branch, 2Institute of Brain Science, National Yang-Ming University, 3Sleep Research Center, National Yang-Ming University, 4Department of Psychiatry, Cathay General Hospital, Taipei, 5Department of Psychiatry, National Taiwan University Hospital, 6Department of Psychiatry, Medical College, National Taiwan University, Taipei, TaiwanBackground: Health-related quality of life (HRQoL remains poor among heroin users, even after being treated with methadone. Evidence regarding self-reported psychopathology and HRQoL in heroin users is also limited. The present study aimed to investigate the association between self-reported psychopathology and HRQoL in Asian heroin users treated with methadone.Methods: Thirty-nine heroin users treated with methadone and 39 healthy controls were recruited. Both groups self-reported on demographic data, the Brief Symptom Rating Scale, EuroQoL-5D, and World Health Organization Questionnaire on Quality of Life: Short Form. We compared clinical characteristics, psychopathology, and HRQoL between the two study groups. Correlation and regression analyses were conducted to explore the association between psychopathology and HRQoL in the heroin user group.Results: Heroin users had more psychopathology and worse HRQoL than healthy controls. The HRQoL of heroin users had significant correlations with Brief Symptom Rating Scale scores. HRQoL could be predicted by depression, anxiety, paranoia, and additional symptoms (ie, poor appetite and sleep difficulties independently.Conclusion: Self-reported psychopathology, depression, anxiety, paranoia, poor appetite, and sleep difficulties had a negative impact on each domain of HRQoL among heroin users treated with methadone. The importance of the environmental domain of HRQoL is discussed. Clinicians

  17. Health-related quality of life in Parkinson's disease patients in northeastern Sicily, Italy An ecological perspective

    Institute of Scientific and Technical Information of China (English)

    Letteria Spadaro; Lilla Bonanno; Giuseppe Di Lorenzo; Placido Bramanti; Silvia Marino

    2013-01-01

    Parkinson's disease has a negative impact on health-related quality of life in Parkinson's disease patients. Depression, cognitive impairment, coping strategies, dyskinesia, gait disorders and complications of dopaminergic drugs are the variables that most affect health-related quality of life. The ecological model of human development focuses attention on both individual and social environmental factors as targets for health interventions. From this perspective, the aim of this cross-sectional survey was to evaluate the influence of gender, family size and perceived autonomy on health-related quality of life in Parkinson's disease patients in northeastern Sicily, Italy. Ninety Parkinson's disease patients, attending the Movement Disorders Clinic at IRCCS Centro Neurolesi "Bonino-Pulejo" (Messina), were consecutively enrolled. The Unified Parkinson Disease Rating Scale motor subscale (UPDRS-III) scores, the Parkinson Disease Questionnaire-39 Item scores (as a disease-specific measure of health-related quality of life), scores on the Short Form (36) Health Survey Questionnaire (as a generic measure), and answers to a brief checklist were recorded.A total of 85 Parkinson's disease patients (49% males and 51% females; mean age 70.8 ± 8.6 years; mean UPDRS-III 24.15 ± 6.55; mean disease duration 5.52 ± 4.65 years) completed the booklet of questionnaires. In the multivariate regression analysis, we included clinical and social variables as independent predictors of health-related quality of life. Our results suggest a potential compounding effect of ecological intrapersonal and interpersonal levels on health-related quality of life outcomes. Gender, self-evaluated autonomy and family size significantly impacted health-related quality of life. If quality of life is used as an indicator of treatment outcomes, an ecological perspective of the case history will be important to disclose relevant prognostic information and trigger personalized health care interventions.

  18. Measuring health-related quality of life for child maltreatment: a systematic literature review

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    Prosser Lisa A

    2007-07-01

    Full Text Available Abstract Background Child maltreatment causes substantial morbidity and mortality in the U.S. Morbidity associated with child maltreatment can reduce health-related quality of life. Accurately measuring the reduction in quality of life associated with child maltreatment is essential to the economic evaluation of educational programs and interventions to reduce the incidence of child maltreatment. The objective of this study was to review the literature for existing approaches and instruments for measuring quality-of-life for child maltreatment outcomes. Methods We reviewed the current literature to identify current approaches to valuing child maltreatment outcomes for economic evaluations. We also reviewed available preference-based generic QOL instruments (EQ-5D, HUI, QWB, SF-6D for appropriateness in measuring change in quality of life due to child maltreatment. Results We did not identify any studies that directly evaluated quality-of-life in maltreated children. We identified 4 studies that evaluated quality of life for adult survivors of child maltreatment and 8 studies that measured quality-of-life for pediatric injury not related to child maltreatment. No study reported quality-of-life values for children younger than age 3. Currently available preference-based QOL instruments (EQ-5D, HUI, QWB, SF-6D have been developed primarily for adults with the exception of the Health Utilities Index. These instruments do not include many of the domains identified as being important in capturing changes in quality of life for child maltreatment, such as potential for growth and development or psychological sequelae specific to maltreatment. Conclusion Recommendations for valuing preference-based quality-of-life for child maltreatment will vary by developmental level and type of maltreatment. In the short-term, available multi-attribute utility instruments should be considered in the context of the type of child maltreatment being measured. However

  19. Impact of prosthodontic treatment on the oral health related quality of life in a maxillectomy patient with multiple impairments.

    Science.gov (United States)

    Faheemuddin, Muhammad; Yazdanie, Nazia; Nawaz, Muhammad Sohaib

    2014-01-01

    Oral Health Related Quality of Life is an important component in the treatment of a patient. Patients with multiple impairments have a compromised quality of life, which is further worsened by ablative maxillary surgery. A properly made oral prosthesis aids in the daily life functions and therefore, has a positive impact on the quality of life of the patient. This article discusses a case in which prosthodontic treatment improved the Oral Health Related Quality of Life in a maxillectomy patient having multiple impairments. PMID:25603688

  20. Approach to the role of the pharmacist in health related quality of life

    Directory of Open Access Journals (Sweden)

    Tafur Valderrama E

    2006-03-01

    Full Text Available To improve health related quality of life (HRQoL is a main objective of pharmaceutical care. The aim of the present study was to identify the knowledge, attitude and performance of community pharmacists on the assessment and the use of HRQoL tools. The study was an observational based on an emailed survey during March to May 2005. A questionnaire focused on quality of life and pharmacy practice was sent to the pharmacists included in Pharmaceutical Care Center (CAF-STADA, a total of 1601. Literature on HRQoL and pharmacy practice and specifically MOS SF-36was sent to the pharmacists surveyed: then, a link to a webpage containing a validated questionnaire to gather their opinions. Results showed that, although pharmacists are not much aware HRQoL, they are show a very positive attitude to use tools for evaluate patients’ HRQoL. They recognize their need for supplementary education and training. Additionally, pharmacists state to be subjectively assessing HRQoL in their patients, without documenting it. These results demonstrate the potential role of the pharmacist in assessing HRQoL. This assessment could be included in pharmacotherapy follow-up, in order to assess the outcomes on quality of life, as stated in original definition of pharmaceutical care.

  1. Health-related quality of life in breast cancer patients: A bibliographic review of the literature from 1974 to 2007

    Directory of Open Access Journals (Sweden)

    Montazeri Ali

    2008-08-01

    cancer patients receiving chemotherapy might experience several side-effects and symptoms that negatively affect their quality of life. Adjuvant hormonal therapies also were found to have similar negative impact on quality of life, although in general they were associated with improved survival. Quality of life as predictor of survival-similar to known medical factors, quality of life data in metastatic breast cancer patients was found to be prognostic and predictive of survival time. Psychological distress-anxiety and depression were found to be common among breast cancer patients even years after the disease diagnosis and treatment. Psychological factors also were found to predict subsequent quality of life or even overall survival in breast cancer patients. Supportive care-clinical treatments to control emesis, or interventions such as counseling, providing social support and exercise could improve quality of life. Symptoms-Pain, fatigue, arm morbidity and postmenopausal symptoms were among the most common symptoms reported by breast cancer patients. As recommended, recognition and management of these symptoms is an important issue since such symptoms impair health-related quality of life. Sexual functioning-breast cancer patients especially younger patients suffer from poor sexual functioning that negatively affect quality of life. Conclusion There was quite an extensive body of the literature on quality of life in breast cancer patients. These papers have made a considerable contribution to improving breast cancer care, although their exact benefit was hard to define. However, quality of life data provided scientific evidence for clinical decision-making and conveyed helpful information concerning breast cancer patients' experiences during the course of the disease diagnosis, treatment, disease-free survival time, and recurrences; otherwise finding patient-centered solutions for evidence-based selection of optimal treatments, psychosocial interventions, patient

  2. Health-related quality of life in French adolescents and adults: norms for the DUKE Health Profile

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    Collin Jean-François

    2011-05-01

    Full Text Available Abstract Background The continual monitoring of population health-related quality of life (HRQoL with validated instruments helps public health agencies assess, protect, and promote population health. This study aimed to determine norms for the French adolescent and adult general population for the Duke Health Profile (DUKE questionnaire in a large representative community sample. Methods We randomly selected 17,733 French people aged 12 to 75 years old in 2 steps, by households and individuals, from the National Health Barometer 2005, a periodic population study by the French National Institute for Prevention and Health Education. Quality of life and other data were collected by computer-assisted telephone interview. Results Normative data for the French population were analyzed by age, gender and self-reported chronic disease. Globally, function scores (best HRQoL=100 for physical, mental, social, and general health, as well as perceived health and self-esteem, were 72.3 (SEM 0.2, 74.6 (0.2, 66.8 (0.1, 71.3 (0.1, 71.3 (0.3, 76.5 (0.1, respectively. Dysfunction scores (worst HRQoL=100 for anxiety, depression, pain and disability domains were 30.9 (0.1, 27.6 (0.2, 34.3 (0.3, 3.1 (0.1, respectively. Conclusion The French norms for adolescents and adults for the DUKE could be used as a reference for other studies assessing HRQoL, for specific illnesses, in France and for international comparisons.

  3. Health-related quality of life after radical prostatectomy or radiotherapy

    International Nuclear Information System (INIS)

    We compared general and disease specific health related quality of life (QOL) after surgery and radiotherapy for prostate cancer. We performed a retrospective survey of patients treated between 1992 and 2001. General and disease specific health related QOL were assessed by the short form 36 health survey questionnaire (SF-36) and the University of California-Los Angels Prostate Cancer Index (UCLA PCI). We mailed questionnaires of QOL survey and obtained from 143 and 73 men who treated surgery and radiotherapy. The median ages of surgery and radiation group were 70.9 and 79.2 years old, and the median periods after treatment were 2.7 and 2.0 years, respectively. Physical function, role physical, social functioning and mental health were higher score in surgery group than radiation group, however, general health perceptions was higher in radiation group among SF-36. Surgery group had worse urinary function and better sexual function compared with radiation group. Multi-variable analysis showed that scores of social functioning, mental health and sexual function were most influenced by each modality, the scores of physical function, role physical, urinary function and sexual bother were most influenced by age, and the score of general health perceptions and body pain was most influenced by the existence of recurrence. This cross-sectional survey cleared the differences of QOL after surgery and radiotherapy, and the influences of each modality. However, because of difference in background of each group, longitudinal investigation will need to aid patients in the decision making process. (author)

  4. The association of drooling and health-related quality of life in children with cerebral palsy

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    Chang SC

    2012-12-01

    Full Text Available Shih-Chung Chang,1 Chin-Kai Lin,2 Li-Chen Tung,3 Nai-Yin Chang11Department of Physical Medicine and Rehabilitation, School of Medicine, Chung Shang Medical University Hospital, Taichung, Taiwan; 2Program of Early Intervention, Department of Early Childhood Education, National Taichung University of Education, Taichung, Taiwan; 3Department of Physical Medicine and Rehabilitation, Chi Mei Medical Center, Tainan, TaiwanObjective: To investigate the association between drooling in children with cerebral palsy (CP and their health-related quality of life (HRQOL, as well as the possible variables that predict their HRQOL.Method: A cross-sectional design was used for this study. Children with CP, without other identified disease, aged 2 to 6 years, who drool (n = 33 or did not drool (n = 14, were included. The dependent variables were the physical health summary scores and the psychosocial health summary scores of the Pediatric Quality of Life Inventory version 4.0. The t test, Pearson product–moment correlation, Mann–Whitney U test and stepwise regression analysis were used for statistical analysis.Results: The physical health and psychosocial health summary scores of the children that drooled (16.29 ± 15.97 and 42.92 ± 17.57, respectively were lower than for the children that did not drool (31.97 ± 22.22 and 57.09 ± 12.21, respectively; P < 0.01. The drooling ranking score was negatively correlated with the physical health summary score (r = −0.355; P < 0.05 and the psychosocial health summary score (r = −0.381; P < 0.01. The stepwise regression showed that gross motor development and the drooling ranking score predicted 56.6% of the variability of the physical health summary score (R2 = 0.566; P < 0.01. The language development score predicted 25.6% of the variability of the psychosocial health summary score (R2 = 0.256; P < 0.01.Conclusion: Drooling was associated with a lower HRQOL. Prediction of the physical health summary score was

  5. Predictors of health-related quality of life in adult ambulatory independence neuromuscular disease patients

    International Nuclear Information System (INIS)

    To evaluate the health related quality of life (HRQoL) of totally independent ambulatory neuromuscular disease (NMD) patients in comparison with age matched healthy control subjects, and to assess associations between socio demographic variables and HRQoL in totally independent NMD patients. Ninety-nine adult patients with a diagnosis of NMD referred to the Physical Therapy Department of the Health Sciences Faculty of Hacettepe University, Ankara, Turkey between 2007 and 2009 were included in the study. The Functional Independence Measurement and the Nottingham Health Profile (NHP) were the main outcomes to assess independence level in activities of daily living and quality of life. The HRQoL score as measured by NHP was high (worse) in patients than healthy controls, and the difference between the 2 groups was significant for energy, physical mobility, and total score. Employed NMD patients scored significantly lower (better) than those unemployed in the majority of NHP domains. The genders and duration of illness displayed no significant difference in all dimension scores. All NMD patients had a poorer HRQoL than with healthy subjects with respect to energy, physical mobility dimensions, and total score. Furthermore, occupation was found to be a main factor that affects HRQoL in adult ambulatory NMD patients. (author)

  6. Parental reports of the oral health-related quality of life of children with cerebral palsy

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    Abanto Jenny

    2012-06-01

    Full Text Available Abstract Background The severity of physical and mental impairments and oral problems, as well as socioeconomic factors, may have an impact on quality of life of children with cerebral palsy (CP. The aim of this research was to assess the impact of impairments and oral health conditions, adjusted by socioeconomic factors, on the Oral Health-Related Quality of Life (OHRQoL of children with CP using their parents as proxies. Methods Sixty children, between 6-14 years of age were selected. Their parents answered a children’s OHRQoL instrument (5 domains which combines the Parental-Caregivers Perception Questionnaire (P-CPQ and Family Impact Scale (FIS. The severity of dental caries, type of CP, communication ability, gross motor function, seizures and socioeconomic conditions were assessed. Results Considering the total score of the OHRQoL instrument, only the reduction of communication ability and dental caries severity had a negative impact on the OHRQoL (p  Conclusions The severity of dental caries, communication ability, and family income are conditions strongly associated with a negative impact on OHRQoL of children with CP.

  7. Health-Related Quality of Life in Patients with MPS II.

    Science.gov (United States)

    Needham, Mary; Packman, Wendy; Quinn, Natasha; Rappoport, Maxwell; Aoki, Christa; Bostrom, Alan; Cordova, Matthew; Macias, Sandra; Morgan, Cynthia; Packman, Seymour

    2015-08-01

    Mucopolysaccharidosis type II (MPS II), also known as Hunter syndrome, is a chronic and progressive X-linked lysosomal disease that mainly affects males. The National MPS Society (2013) reports that MPS II affects 1 in 100,000 to 1 in 150,000 males worldwide. Two distinct forms of the disease are based on age of onset and clinical course: attenuated and severe. MPS II affects many organ systems including the nervous, cardiovascular, gastrointestinal and respiratory systems. Clinical manifestations can include progressive hearing loss, mental impairment, and enlarged liver and spleen. This study focuses on the health-related quality of life of individuals (HRQOL) with MPS II as measured by the parent and self-report versions of the Pediatric Quality of Life Inventory (PedsQL™). Both parents of patients with MPS II as well as patients themselves reported lower scores on all domains of the PedsQL™ (physical, emotional, social and school functioning) indicating that children with MPS II have an overall lower HRQOL when compared to a healthy sample. When compared with patients with other chronic illnesses (cancer, MSUD, galactosemia,), the MPS II sample had significantly lower scores on a number of PedsQL™ scales, suggesting an overall lower HRQOL. No significant relationships were found using scores from parent or self report PedsQL™ measures and length of time on ERT. PMID:25395377

  8. The Assessment of Health-Related Quality of Life in Scleroderma-Interstitial Lung Disease

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    Shahrzad M Lari

    2014-05-01

    Full Text Available Introduction: Pulmonary involvement is the most common cause of mortality and disability in patients with systemic sclerosis and it significantly affects the quality of life in these patients. Therefore, early diagnosis and treatment of pulmonary involvement seems necessary in patients with SSc. In this study, we aimed to assess the health-related quality of life (HRQoL in patients with Scleroderma-Interstitial Lung Disease (SSc-ILD and its relationship with pulmonary function parameters. Materials and Methods: Considering the inclusion and exclusion criteria, 25 patients with SSc-ILD were enrolled in this cross-sectional study from April 2012 to June 2013. Full tests of lung function, including body plethysmography and diffusing capacity of the lungs for carbon monoxide (DLCO, 6-minute walk distance (6MWD, and pulse oximetry were performed. The HRQoL was assessed using St. George’s and CAT questionnaires; also, dyspnea was evaluated for all the patients, using modified medical research council (MMRC scale. Afterwards, the relationship between the total scores of HRQoL questionnaires and the severity of lung disease was analyzed, based on the recorded variables. Results: The mean age of the patients was 40.36±9.50 years and the mean duration of the disease was 7.16±4.50 years. A statistically significant inverse correlation was observed between 6MWD (r=-0.50, P=0.01, DLCO (r=-0.67, P

  9. Pathological Motivations for Exercise and Eating Disorder Specific Health-Related Quality of Life

    Science.gov (United States)

    Cook, Brian; Engel, Scott; Crosby, Ross; Hausenblas, Heather; Wonderlich, Stephen; Mitchell, James

    2014-01-01

    Objective To examine associations among pathological motivations for exercise with eating disorder (ED) specific health-related quality of life (HRQOL). Method Survey data assessing ED severity (i.e., Eating Disorder Diagnostic Survey), ED specific HRQOL (i.e., Eating Disorders Quality of Life Instrument), and pathological motivations for exercise (i.e., Exercise Dependence Scale) were collected from female students (N = 387) at seven universities throughout the United States. Regression analyses were conducted to examine the associations among exercise dependence, ED-specific HRQOL and ED severity, and the interaction of exercise dependence and ED severity on HRQOL scores. Results The overall model examining the impact of ED severity and exercise dependence (independent variables) on HRQOL (dependent variable) was significant and explained 16.1% of the variance in HRQOL scores. Additionally, the main effects for ED severity and exercise dependence and the interaction among ED severity and exercise dependence were significant, suggesting that the combined effects of ED severity and exercise dependence significantly impacts HRQOL. Discussion Our results suggest that pathological motivations for exercise may exacerbate ED’s detrimental impact on HRQOL. Our results offer one possible insight into why exercise may be associated with deleterious effects on ED HRQOL. Future research is needed to elucidate the relationship among psychological aspects of exercise, ED, and HRQOL. PMID:24136170

  10. Oral health-related quality of life of edentulous patients after complete dentures relining

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    Krunić Nebojša

    2015-01-01

    Full Text Available Background/Aim. Tooth loss affects oral health-related life quality. More than a third of edentulous patients are not fully satisfied with their complete dentures and mainly complain of insufficient stability, retention, and pain during mastication. Solving the problem may include relining by materials that are based on silicone or acrylic. The aim of this study was to determine the level of patients’ satisfaction before and after relining upper dentures with soft and rigid liners. Methods. The patients (n = 24 were divided into two study groups. Maxillary denture relining of the first group of patients was performed with hard acrylic based resins while in the second group of patients complete denture was relined with a silicone-based soft liner. They were asked the questions from the specifically adapted the Oral Health Impact Profile Questionnaire for edentulous patients before and three months after relining dentures. Results. After relining the patients showed a higher degree of satisfaction with their dentures in all the tested domains (masticatory function, psychological discomfort, social disability and retention and hygiene. The patients with soft denture relines were more satisfied. Conclusion. Relining of maxillary complete dentures significantly positively impacts the quality of life of patients in all the tested domains (masticatory function, psychological discomfort, social disability, pain and oral hygiene. Better results were achieved using a silicone-based soft liner, which recommends it as the material of choice for relining dentures.

  11. The Impact of Orthognathic Surgery on Oral Health-Related Quality of Life

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    Reza Tabrizi

    2013-12-01

    Full Text Available Introduction: This study aimed to measure the changes in oral health-related quality of life of the patients, referred to Shahid Chamran Hospital in Shiraz before and after the orthognathic surgery. Methods: This prospective study was performed using the 14-item oral health impact profile (OHIP-14 questionnaire. The questionnaires were given both before and four months after the orthognathic surgery to all the patients referred to Shahid Chamran Hospital of Shiraz between 20th of November 2012 and 20th of February 2013. The patients were asked about their motivation for surgery and the responses were classified as functional, esthetic or a combination of functional and esthetic problems. The data achieved from all the questions before and after the surgery were analyzed using repeated measures test. Results: Twenty eight patients including 10 men and 18 women participated in this study. The mean scores of quality of life after the surgery decreased significantly compared to that before the treatment (P

  12. Health-related quality of life among colorectal cancer patients in Malaysia: a study protocol

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    Magaji Bello

    2012-09-01

    Full Text Available Abstract Background Colorectal cancer is a major public health problem in Malaysia. However, it is also one of the most treatable cancers, resulting in significant numbers of survivors. Therefore, the impact of surviving treatment for colorectal cancer on health related quality of life is important for the patients, clinicians and policy makers, and may differ in different cultures and populations. The aim of this study was to validate the Malaysian versions of the European Organization for Research and Treatment of Cancer quality of life instruments among colorectal cancers patients. Methods/design This is a cross sectional multi centre study. Three hospitals were included, the University of Malaya Medical Centre, the Universiti Kebangsaan Malaysia Medical Centre and Hospital Tuanku Jaafar Seremban. Malaysian citizens and permanent residence were studied and demographic and clinical information obtained from hospital records. The European Organization for Research and Treatment of Cancer Quality of life Core 30, colorectal cancer CR29, and the colorectal cancer liver metastasis LMC 21 were used and an observer assessment of performance obtained with the Karnofsky Performance Scale. Questionnaires were translated into three most commonly spoken languages in Malaysia (Bahasa Malaysia, Chinese and Tamil, then administered, scored and analyzed following the developers’ guidelines. Ethical approval was obtained from the participating centres. Tests of reliability and validity were performed to examine the validity of these instruments. Conclusion The result of pilot testing shows that the use of the Malaysian versions of EORTC QLQ C30, CR29 instruments is feasible in our sample of colorectal cancer patients. Instructions for completion as well as questions were well understood except the questions on the overall quality of life, overall health status and sexual activity. Thus we anticipate obtaining good psychometric properties for the instruments

  13. Health-related quality of life in patients with skull base tumours.

    LENUS (Irish Health Repository)

    Kelleher, M O

    2012-02-03

    The objective of the investigation was to report on the health-related quality of life (HRQoL) of patients diagnosed with skull base tumours using the Short Form Health Survey questionnaire (SF-36). Those patients suffering with vestibular schwannoma were examined to determine the effect facial nerve function had on their quality of life. It took place at the tertiary referral centre at the Department of Clinical Neurosciences, Western General Hospital, Edinburgh. A prospective study of 70 consecutive patients was taken, who harboured the following tumours: 54 vestibular schwannomas, 13 meningiomas, two haemangioblastomas and one hypoglossal schwannoma. Patients were interviewed using the short form 36 (SF-36) questionnaire. Facial nerve function was assessed in those patients who had vestibular schwannomas. The entire cohort of live skull base patients were assessed after a median follow-up time of 38.4 months. Patients with vestibular schwannoma treated conservatively with interval MRI had a quality of life similar to t he normal population. Those who underwent surgery had a significant difference in two of the SF-36 domains. No statistically significant correlation was found at final assessment between the degree of facial nerve functioning and any of the domains of SF-36. Patients with non-vestibular tumours had an impaired HRQoL in seven of the eight domains. Patients with skull base tumours have a significant impairment of their HRQoL. A conservative policy of follow up with interval MRI for patients with small vestibular schwannomas may therefore be more appropriate to preserve their HRQoL. Facial nerve outcome has little influence on quality of life in vestibular schwannoma patients.

  14. Health-related quality of life in dialysis patients with constipation: a cross-sectional study

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    Zhang JS

    2013-06-01

    Full Text Available JiSheng Zhang,1,* CongYang Huang,1,* YanLi Li,1 Jun Chen,2 FangYuan Shen,1 Qiang Yao,3 JiaQi Qian,4 BeiYan Bao,1 XuPing Yao51Division of Nephrology, School of Medicine, Ningbo Urology and Nephrology Hospital, Ningbo University, Ningbo, Zhejiang, People's Republic of China; 2Blood Purification Center, School of Medicine, Ningbo Urology and Nephrology Hospital, Ningbo University, Ningbo, Zhejiang, People's Republic of China; 3Baxter Healthcare Pty Ltd, Shanghai, People's Republic of China; 4Division of Nephrology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China; 5Division of Urology, School of Medicine, Ningbo Urology and Nephrology Hospital, Ningbo University, Ningbo, Zhejiang, People's Republic of China *These authors contributed equally to this workObjectives: To evaluate differences in the health-related quality of life (HRQoL between patients with constipation receiving hemodialysis (HD and those receiving peritoneal dialysis (PD.Methods: In this cross-sectional study, 605 dialysis patients (478 HD cases and 127 PD cases; all patients were older than 18 years from our hospital were included. A questionnaire was used to evaluate their constipation statuses. The effect of constipation on HRQoL was assessed, using the Chinese version of the 12-item short-form (SF-12 general health survey. Karnofsky score, sociodemographic, and clinical data were also collected. We performed multiple logistic regression analysis to define independent risk factors for constipation and impaired HRQoL.Results: A total of 605 participants (326 men [53.9%] and 279 women [46.1%] were surveyed. The incidence of constipation was 71.7% in HD patients and 14.2% in PD patients. Dialysis patients with constipation had significantly lower mean SF-12 Physical Component Summary scale and Mental Component Summary scale scores than the nonconstipation group (P < 0.05, whereas HD patients had better SF-12 Physical Component

  15. The MacNew Heart Disease health-related quality of life instrument: A summary

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    Guyatt Gordon

    2004-01-01

    Full Text Available Abstract Background The measurement of health, the effects of disease, and the impact of health care include not only an indication of changes in disease frequency and severity but also an estimate of patients' perception of health status before and after treatment. One of the more important developments in health care in the past decade may be the recognition that the patient's perspective is as legitimate and valid as the clinician's in monitoring health care outcomes. This has lead to the development of instruments to quantify the patients' perception of their health status before and after treatment. Methods We review evidence supporting the measurement properties of the MacNew Heart Disease Health-related Quality of Life [MacNew] Questionnaire which was designed to evaluate how daily activities and physical, emotional, and social functioning are affected by coronary heart disease and its treatment. Results Reliability was demonstrated by using internal consistency and the intraclass correlation coefficients for the three domains in the Dutch, English, Farsi, German, and Spanish versions of the MacNew. With internal consistency and intraclass correlation coefficients =>0.73, reliability is high. Validity of the MacNew was examined with factor analysis and three core underlying factors, physical, emotional, and social, were identified, explaining 63.0 – 66.5% of the observed variance and replicated in the translations with psychometric data. Construct validity of the MacNew was further demonstrated by extensive substantiation of the logical relationships, defined a priori, between items and other comparison tools. The MacNew is responsive and sensitive to changes in HRQL following various interventions for patients with heart disease with 11 of 13 effect size statistics >0.80. Taking an average of 10 minutes or less to complete, the respondent-burden for the MacNew is low and its acceptability is demonstrated by response rates of over 90

  16. Coping and emotional distress in relation to health-related quality of life in Slovene patients with cancer

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    Tanja Žagar

    2011-08-01

    Full Text Available Managing emotional distress triggers different coping strategies for coping with stress in cancer patients. Effective coping affects health – related quality of life and psychosocial adaptation. This study was performed to determine coping strategies, and their connectedness to emotional distress (anxiety and depression and health – related quality of life in cancer patients. Study was carried out on 70 cancer patients, in inpatient and outpatient setting. Depressive symptoms were measured with Beck Depression Inventory BDI-SH, anxiety with State Trait Anxiety Inventory STAI-1, coping strategies with Coping Response Inventory CRI and health – related quality of life with Quality of Life Questionnaire QOLQ- 30. A negative, statistically important relationship was found between active strategies, emotional distress and quality of life. Recognition of emotional distress and ways of coping in cancer patients are important for quality of health care.

  17. Health-related quality of life and well-being in adults with idiopathic inflammatory myopathy.

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    Armadans-Tremolosa, Imma; Selva-O'Callaghan, Albert; Visauta-Vinacua, Bienvenido; Guilera, Georgina; Pinal-Fernández, Iago; Vilardell-Tarrés, Miquel

    2014-08-01

    Health-related quality of life (HRQoL) and well-being are concepts that attempt to objectively capture a person's subjective perceptions of vitality and energy. Our objectives were to determine HRQoL and well-being in adult patients diagnosed with inflammatory myopathy who attended at our outpatient clinic and to investigate clinical and biological correlations with these concepts. Sixty-two patients (52 women), with a mean age of 50.7 years, were evaluated in this cross-sectional study-47 with dermatomyositis and 15 with polymyositis. Disease damage and activity were assessed with the International Myositis Assessment and Clinical Studies-validated instruments. Manual muscle testing was used to evaluate muscle strength. Quality of life was evaluated with the WHO instrument (WHO Quality of Life Measure (WHOQOL-BREF)), adapted for use in the Spanish population, and well-being with the WHO-Five Well-Being Index (WHO-5). t tests were conducted to examine differences in HRQoL and well-being outcomes in relation to several disease- and patient-related variables. Correlation analyses were performed with the Pearson correlation coefficient. None of the clinical or biological variables analyzed was significantly associated with a poorer HRQoL or well-being. No differences in HRQoL or WHO-5 well-being score were found between the two myositis subgroups (dermatomyositis vs. polymyositis). Disease activity and muscle weakness were negatively associated with the physical and environmental domains of the HRQoL, respectively (p < 0.002), but not with well-being. Disease duration did not have a significant impact on HRQoL or well-being. In adult patients with myositis, disease activity and muscle weakness are associated with poorer HRQoL in the physical health and environmental domains, respectively. PMID:24894104

  18. Health-related quality of life in glioma patients in China

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    Lin Hong

    2010-06-01

    Full Text Available Abstract Background Health-related quality of life (HRQOL has been increasingly emphasized in cancer patients. There are no reports comparing baseline HRQOL of different subgroups of glioma patients prior to surgery. Methods HRQOL assessments by the standard Chinese version of the European Organization for Research and Treatment of Cancer Quality of Life Core Questionnaire 30 (EORTC QLQ-C30, version 3.0, the Mini-Mental State Examination and Karnofsky Performance Status were obtained from glioma patients prior to surgery. Results Ninety-two pathologically confirmed glioma patients were recruited. There were 84.8% patients with emotional impairment, 75% with social and cognitive impairment, 70.7% with physical impairment, and 50% with role impairment. Eighty-two percent of patients reported fatigue symptoms, 72.8% reported pain, 50% reported appetite loss, 39.1% reported insomnia, and 36.9% reported nausea/vomiting, whereas other symptoms (dyspnea, diarrhea, constipation in the QLQ-C30 were reported by fewer than 30% of patients. Fatigue and pain symptoms and all "functioning" scales were strongly correlated with global health status/quality of life (QoL. Fatigue was strongly related to all functioning scales, pain, appetite loss, and global health status/QoL. No difference in baseline HRQOL prior to surgery was reported between females and males, among different lesion locations, or between normal- and abnormal-cognition subgroups of glioma patients. Age, KPS, WHO grade, and tumor recurrence significantly affected HRQOL in glioma patients. Conclusions These data provided the baseline HRQOL in glioma patients prior to surgery in China. Most pre-surgery glioma patients indicated emotional, social, cognitive, physical, and role impairment. Fatigue, pain, appetite loss, insomnia, and nausea/vomiting were common in these patients. The fatigue and pain symptoms and all types of functioning strongly affected global health status/QoL. Old age, worse

  19. Defensive coping and health-related quality of life in chronic kidney disease: a cross-sectional study

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    Ikonomou Margarita

    2011-06-01

    Full Text Available Abstract Background Coping with the stresses of chronic disease is considered as a key factor in the perceived impairment of health related quality of life (HRQL. Little is known though about these associations in chronic kidney disease (CKD. The present study aimed to investigate the relationship of defensive coping and HRQL among patients in different CKD stages, after adjusting for psychological distress, sociodemographic and disease-related variables. Methods The sample consisted of 98 CKD patients, attending a university nephrology department. Seventy-nine (79 pre-dialysis patients of disease stages 3 to 4 and 19 dialysis patients were included. HRQL was assessed by the 36-item Short-Form health survey (SF-36, defensive coping by the Rationality/Emotional Defensiveness (R/ED scale of the Lifestyle Defense Mechanism Inventory (LDMI and psychological distress by the depression and anxiety scales of the revised Hopkins Symptom CheckList (SCL-90-R. Regression analyses were carried out to examine the association between SF-36 dimensions and defensive coping style. Results Patients on dialysis had worse scores on SF-36 scales measuring physical aspects of HRQL. In the fully adjusted analysis, a higher defensive coping score was significantly associated with a lower score on the mental component summary (MCS scale of the SF-36 (worse mental health. In contrast, a higher defensive score showed a small positive association with the physical component summary (PCS scale of the SF-36 (better health, but this was marginally significant. Conclusions The results provided evidence that emotional defensiveness as a coping style tends to differentially affect the mental and the physical component of HRQL in CKD. Clinicians should be aware of the effects of long-term denial and could examine the possibility of screening for defensive coping and depression in recently diagnosed CKD patients with the aim to improve both physical and mental health.

  20. Overt and subtle discrimination, subjective well-being and physical health-related quality of life in an obese sample.

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    Magallares, Alejandro; Benito de Valle, Pilar; Irles, Jose Antonio; Jauregui-Lobera, Ignacio

    2014-01-01

    Obesity represents a serious health issue affecting millions of people in Western industrialized countries. The severity of the medical problems it causes is paralleled by the fact that obesity has become a social stigma that affects the psychological health-related quality of life of individuals with weight problems. Our study, with 111 obese patients of a Spanish hospital, focused specifically on how overt and subtle discrimination is related to subjective well-being (affect balance and life satisfaction) and physical health-related quality of life. It was shown that overt (r = -.28, p Baron and Kenny procedure. Finally, it is discussed the relationship between discrimination, subjective well-being and physical health-related quality of life in obese people. PMID:26054408

  1. Fitness and health-related quality of life dimensions in community-dwelling middle aged and older adults

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    Olivares Pedro R

    2011-12-01

    Full Text Available Abstract Background The aim of the present study was to identify the physical fitness (PF tests of a multi-component battery more related to the perception of problems in each dimension of the health-related quality of life (HRQoL assessed by the EuroQol 5 dimensions 3 level questionnaire (EQ-5D-3L in community-dwelling middle-aged and older adults Methods A cross-sectional study was conducted with 7104 participants (6243 females and 861 males aged 50-99 years who were recruited in the framework of the Exercise Looks After You Program, which is a public health program designed to promote physical activity (PA in community-dwelling middle-aged and older adults. Participants were assessed by the EQ-5D-3L questionnaire and a battery of fitness tests. The responses to each EQ-5D-3L dimension were collapsed into a two-tier variable consisting of «perceive problems» and «do not perceive problems». Correlation coefficients for the relationships between the HRQoL variables, between the PF variables, and between the HRQoL and PF variables were obtained. Two logistic regression models, one adjusted and one unadjusted, were developed for each EQ-5D-3L dimension. Results There were significant correlations between all variables except anxiety/depression and the back scratch test. The PF tests that correlated best with the HRQoL dimensions were the Timed Up-and-Go Test (TUG and the 6-min walk; pain/discomfort and anxiety/depression correlated less well. All PF tests correlated, especially the TUG and 6-min walk tests. Unadjusted logistic models showed significant goodness of fit for the mobility and pain/discomfort dimensions only. Adjusted logistic models showed significant goodness of fit for all dimensions when the following potential confounding variables were included: age, gender, weekly level of PA, smoking and alcohol habits, body mass index, and educational level. For all dimensions, the highest odds ratios for the association with PF tests were

  2. Determinants of health-related quality of life worsening in patients with chronic obstructive pulmonary disease at one year

    Institute of Scientific and Technical Information of China (English)

    Liang Lirong; Lin Yingxiang; Yang Ting; Zhang Hong; Li Jie; Wang Chen

    2014-01-01

    Background Chronic obstructive pulmonary disease (COPD) is a major cause of morbidity and mortality worldwide and has been the leading cause of death in China.Patients with COPD have significant decrements in their health-related quality of life (HRQL).It is necessary to identify the factors involved in worsening HRQL in order to improve the HRQL of COPD patients.However,evidence from longitudinal studies is limited.The aim of the study was to evaluate the determinants of the deterioration of HRQL in patients with COPD.Methods At baseline,a total of 491 patients with stable COPD received comprehensive assessments,including psychosocial and clinical variables,six minutes walk distance (6MWD),dyspnea grade measured by the 5-grade Medical Research Council (MRC) dyspnea scale,anxiety and depression measured by the hospital anxiety and depression scale and HRQL measured by St.George's Respiratory Questionnaire (SGRQ).Patients were then monitored monthly for 12 months to document COPD exacerbations.At the end of the study period,the SGRQ values were reassessed.A 1-year change in SGRQ total score ≥4 was defined as a deterioration of the HRQL and as the outcome.A total of 450 patients completed the 12-month follow-up and were analyzed in the present study.Results The age (mean±SD) was (65.0±10.6) years and 68.7% of subjects were men.The deterioration of the HRQL was 26.4%.In multivariate Logistic regression,independent and graded associations were found between the baseline MRC dyspnoea grade and the deterioration of HRQL (P=0.012),OR 3.03 (95% CI 1.11-8.24) for patients with MRC dyspnoea grade ≥4 versus patients with MRC dyspnoea grade =1.Similarly,the number of exacerbations during the follow-up was independently and gradually increased with the deterioration of HRQL (P <0.001),OR 3.03 (95% CI 1.9-5.6) for the participants with exacerbations ≥3 versus participants with no exacerbation.The 6MWD evaluated by quartiles was negatively associated with the

  3. Physical activity, health-related quality of life and depression during pregnancy

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    Iva Tendais

    2011-02-01

    Full Text Available This study examines physical activity patterns among women, from pre-pregnancy to the second trimester of pregnancy, and the relationship between physical activity status based on physical activity guidelines and health-related quality of life (HRQoL and depression over pregnancy. 56 healthy pregnant women self-reported physical activity, HRQoL and depression at 10-15 and 19-24 weeks of pregnancy and physical activity before pregnancy. Whereas vigorous leisure physical activity decreased after conception, moderate leisure physical activity and work related physical activity remained stable over time. The prevalence of recommended physical activity was 39.3% and 12.5% in the 1st and 2nd trimesters of pregnancy respectively, and 14.3% pre-pregnancy. From the 1st to the 2nd pregnancy trimester, most physical HRQoL dimensions scores decreased and only mental component increased, independently of physical activity status. No changes in mean depression scores were observed. These data suggest that physical activity patterns change with pregnancy and that physical and mental components are differentially affected by pregnancy course, independently of physical activity status.

  4. Health-related quality of life in type 2 diabetic patients

    International Nuclear Information System (INIS)

    Health-related quality of life (HRQOL) is an important health outcome, representing one of the most important goals of all health interventions. The objectives of this study were to determine HRQOL and the factors affecting it in type 2 diabetic patients. The cross-sectional study was conducted in 5 primary health care (PHC) centers in the Al-Khobar area. From a random sample of 225 type 2 diabetic patients, 216 patients were included in the study along with 216 age, sex and nationality-matched controls. Nine patients refused to participate. Type 2 diabetic patients and controls were interviewed with the translated Arabic SF-12 questionnaire. The mean ages were 50.0+-10.0 years for cases of 49.3+-10.3 years for controls (P=0.526). Type 2 diabetic patients had lower socioeconomic status and educational level than controls. Obesity was significantly higher in diabetic than controls. HRQOL in type 2 diabetic patients was significantly lower than controls. The mean physical component score was 41.3+-8.9 for cases vs. 47.5+-9.5 for controls (P130 mg/dL) in comparison with controlled patients (FPG<-130130 mg/dL) (P<0.05). HRQOL was lower in type 2 diabetic patients than controls and was affected by many factors. Females had lower HRQOL than males, possibly because of a higher incidence of obesity. Uncontrolled diabetic patients had a lower HRQOL than controlled diabetics. Improving HRQOL in diabetic patients is important. (author)

  5. Effect of Counseling on Health Related Quality of Life on Haemodialysis Patients

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    Ramakrishanan Sivakumar

    2012-09-01

    Full Text Available End stage renal disease affects two million patients worldwide. Health related quality of life (HRQoL has recently become a major indicator of health and well-being of patients with kidney disease. The present goal for the treatment of patients with ESRD is not simply to prolong life, but also to provide a better HRQoL. This goal can be achieved through patient counseling. A simple prospective study was used to examine the effect of patient counseling on HRQoL of hemodialysis patients. In the study, a Short Form-36 (SF-36 questionnaire and clinical parameters were used for 52 hemodialysis patients to assess the HRQoL before and after patient counseling. All the Patients were kept under observation for a period of three months to study the effect of patient counseling. After three months period of counseling a significant (p<0.05 improvement was observed for hemodialysis patients. Also HRQoL score was higher for hemodialysis patients after counseling. This study concluded that knowledge of the disease and its management through patient counseling could improve the HRQoL of hemodialysis patients.

  6. Health-related quality of life in significant others of patients dying from lung cancer.

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    Persson, C; Ostlund, U; Wennman-Larsen, A; Wengström, Y; Gustavsson, P

    2008-04-01

    This study compares health-related quality of life (HRQOL) in significant others of patients dying from lung cancer, with a general population sample. Further, it explores the course of HRQOL from diagnosis (T1), at a time point close to the patient's death (T2), and six months after the patient's death (T3). The group comparisons at T1 showed that the significant others scored significantly lower on the scales in the mental domain compared with a general population sample. These results were the same at T3, when the significant others also scored lower on most of the scales in the physical and social domains. In the longitudinal analyses, there were significant changes in four scales, and three patterns of change were identified: a decrease-increase pattern for 'self-rated health' and 'positive affect'; a constant decrease pattern for 'family functioning'; and a decrease-stable pattern for 'satisfaction with family functioning'. Thus, living with inoperable lung cancer in the family and then facing the death of a family member affects most of the HRQOL dimensions. PMID:18477718

  7. Health-Related Quality of Life and Overall Life Satisfaction in People with Serious Mental Illness

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    Amy L. Barnes

    2012-01-01

    Full Text Available Quality of life (QoL in people with schizophrenia and other serious mental illnesses (SMI is an important outcome goal, yet there is no consistent definition of the construct. We examined three aspects of QoL in persons with SMI: overall life satisfaction, physical health-related QoL (HRQoL, and mental HRQoL. This study had two primary aims: first, to examine whether there are differences in physical and mental HRQoL in persons with SMI, and, second, to investigate the cognitive, clinical, and functional correlates of the three QoL indicators. Participants were 48 persons with SMI who completed assessments of QoL, cognition, functional capacity, psychiatric symptomatology, and medical comorbidity. Results indicate that participants experience similar levels of physical and mental HRQoL, and these two constructs are not related to one another. Physical HRQoL is associated with less medical comorbidity, while mental HRQoL is associated with negative and depressive symptoms. Overall life satisfaction was associated with fewer psychiatric symptoms and less medical comorbidity. This study adds to the important literature defining distinct domains of QoL and supports the necessity of addressing both physical and mental health factors as they relate to recovery and well-being among persons with SMI.

  8. Health-related quality of life in diabetic patients with foot ulcers: literature review.

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    Goodridge, Donna; Trepman, Elly; Embil, John M

    2005-01-01

    Foot ulcers are a common, serious, and costly complication of diabetes, preceding 84% of lower extremity amputations in diabetic patients and increasing the risk of death by 2.4-fold over diabetic patients without ulcers. Health-related quality of life (HRQOL) is worse among individuals with diabetes than individuals without diabetes, and complications of diabetes, including foot ulcers, have a major negative effect on HRQOL. Diabetic foot ulcers are associated with reduced mobility and deficits related to activities of daily living that adversely affect HRQOL. Qualitative studies have confirmed clinical observations that diabetic foot ulcers have a huge negative psychological and social effect, including reduction in social activities, increased family tensions for patients and their caregivers (spouses or partners), limited employment, and financial hardship. Quantitative studies confirm the findings of qualitative studies that diabetic foot ulcers exert a negative effect on physical functioning, psychological status, and social situation. Recent advances include the development and validation of disease-specific HRQOL surveys for diabetic patients with foot ulcers. Disease-specific surveys may improve the evaluation of HRQOL as a function of ulcer healing, the effect of different treatment methods on HRQOL, and the relationship between treatment-specific HRQOL, patient compliance, and treatment efficacy. PMID:16301902

  9. Do Quiet Areas Afford Greater Health-Related Quality of Life than Noisy Areas?

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    Kim N. Dirks

    2013-03-01

    Full Text Available People typically choose to live in quiet areas in order to safeguard their health and wellbeing. However, the benefits of living in quiet areas are relatively understudied compared to the burdens associated with living in noisy areas. Additionally, research is increasingly focusing on the relationship between the human response to noise and measures of health and wellbeing, complementing traditional dose-response approaches, and further elucidating the impact of noise and health by incorporating human factors as mediators and moderators. To further explore the benefits of living in quiet areas, we compared the results of health-related quality of life (HRQOL questionnaire datasets collected from households in localities differentiated by their soundscapes and population density: noisy city, quiet city, quiet rural, and noisy rural. The dose-response relationships between noise annoyance and HRQOL measures indicated an inverse relationship between the two. Additionally, quiet areas were found to have higher mean HRQOL domain scores than noisy areas. This research further supports the protection of quiet locales and ongoing noise abatement in noisy areas.

  10. Validity and reliability of a questionnaire for measuring child oral-health-related quality of life.

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    Jokovic, A; Locker, D; Stephens, M; Kenny, D; Tompson, B; Guyatt, G

    2002-07-01

    Oral-health-related quality of life measures that exist are designed for adults. This study aimed to develop and evaluate the CPQ(11-14), a self-report measure of the impact of oral and oro-facial conditions on 11- to 14-year-old children. An item pool was generated with the use of a literature review and interviews with health professionals, parents, and child patients. The 36 items rated the most frequent and bothersome by 83 children were selected for the CPQ(11-14). Validity testing involved a new sample of 123 children. Test-retest reliability was assessed in a subgroup of these children (n = 65). Mean CPQ(11-14) scores were highest for oro-facial (31.4), lower for orthodontic (24.3), and lowest for pedodontic (23.3) patients. There were significant associations between the CPQ(11-14) score and global ratings of oral health (p < 0.05) and overall well-being (p < 0.01). The Cronbach's alpha and intraclass correlation coefficient for the CPQ(11-14) were 0.91 and 0.90, respectively. These results suggest that the CPQ(11-14) is valid and reliable. PMID:12161456

  11. Is Health-Related Quality of Life Associated with Upper and Lower Airway Inflammation in Asthmatics?

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    Nicola Scichilone

    2013-01-01

    Full Text Available Background. Allergic diseases impair health-related quality of life (HR-QoL. However, the relationship between airway inflammation and HR-QoL in patients with asthma and rhinitis has not been fully investigated. We explored whether the inflammation of upper and lower airways is associated with HR-QoL. Methods. Twenty-two mild allergic asthmatics with concomitant rhinitis (10 males, 38 ± 17 years were recruited. The Rhinasthma was used to identify HR-QoL, and the Asthma Control Test (ACT was used to assess asthma control. Subjects underwent lung function and exhaled nitric oxide (eNO test, collection of exhaled breath condensate (EBC, and nasal wash. Results. The Rhinasthma Global Summary score (GS was 25 ± 11. No relationships were found between GS and markers of nasal allergic inflammation (% eosinophils: , ; ECP: , or bronchial inflammation (pH of the EBC: , ; bronchial NO: , ; alveolar NO: , . The mean ACT score was 18. When subjects were divided into controlled (ACT ≥ 20 and uncontrolled (ACT < 20, the alveolar NO significantly correlated with GS in uncontrolled asthmatics (, . Conclusions. Upper and lower airways inflammation appears unrelated to HR-QoL associated with respiratory symptoms. These preliminary findings suggest that, in uncontrolled asthma, peripheral airway inflammation could be responsible for impaired HR-QoL.

  12. Domestic Violence During Pregnancy and Women's Health-Related Quality of Life.

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    Gharacheh, Maryam; Azadi, Shahdokht; Mohammadi, Nooredin; Montazeri, Simin; Khalajinia, Zohre

    2016-02-01

    Domestic violence during pregnancy is a major health problem with significant psychological and physical impairments for pregnant women. To assess the relationship between domestic violence during pregnancy and women's health-related quality of life (HRQoL), a cross-sectional study was conducted on 341 postnatal women who referred to urban health care centers in Gachsaran, Islamic Republic of Iran. Domestic violence was assessed using a questionnaire modified from the Abuse Assessment Screen (AAS), and Iranian version of Short Form-36 questionnaire was used to assess women's HRQoL. The findings of the study showed 44.5% of women reported experiencing domestic violence during pregnancy. All the SF-36 subscales including both physical and mental health dimensions scored lower in the abused women compared to the non-abused women, and differences between the groups in the six subscales of SF-36 except 'physical functioning' and 'bodily pain' were statistically significant (Pviolence during pregnancy is associated with poor HRQoL in abused women. PMID:26383205

  13. Health-related quality of life outcome for oral cancer survivors after surgery and postoperative radiotherapy

    International Nuclear Information System (INIS)

    Health-related quality of life (HRQL) data are becoming an important supplement to information pertaining to treatment outcome for cancer patients. The purpose of this study was to evaluate the HRQL outcome for oral cancer survivors after surgery plus postoperative radiotherapy (RT) and to investigate the variables associated with their HRQL. Sixty-six oral cancer patients with cancer-free survival after surgery plus postoperative RT of >2 years were enrolled. The Short Form-36 (SF-36) questionnaire in the Taiwan Chinese version was self-reported by all participants at the clinics. The linear regression model was used to analyze the socio-demographic and medical-related variables correlated with the physical component summary (PCS) and mental component summary (MCS) in SF-36. The mean scores of the eight functional domains in the SF-36 were markedly lower for oral cancer survivors compared with the Taiwanese and US norms. Those with older age, lower annual family income, more advanced cancer stage and flap reconstruction had significantly worse PCS, and those with lower annual family income, unemployment and more advanced cancer stage reported significantly worse MCS. This model accounts for 63% of variance in PCS, and 51% in MCS. These results provided patient-reported evidence that oral cancer survivors lived with a worse HRQL compared with the general Taiwanese population. Socio-economic factors and cancer stage were important factors correlated with their HRQL. (authors)

  14. Dimensional structure of the oral health-related quality of life in healthy Spanish workers

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    López Joaquín F

    2010-02-01

    Full Text Available Abstract Background Oral health-related quality of life (OHQoL is conceived as a multidimensional construct. Here our aim was to investigate the dimensional structure of OHQoL as measured by the Spanish versions of the Oral Impacts on Daily Performance (OIDP and the Oral Health Impact Profile (OHIP-14 questionnaires applied simultaneously. Methods We recruited a consecutive sample of 270 healthy Spanish workers visiting the Employment Risk Prevention Centre for a routine medical check-up. OHIP-14 was self-completed by participants but the OIDP was completed in face-to-face interviews. An Exploratory Factor Analysis (EFA was performed to identify the underlying dimensions of the OHQoL construct assessed by both instruments. This factorial structure was later confirmed by Confirmatory Factor Analysis (CFA using several estimators of goodness of fit indices. Results EFA and the CFA identified and respectively confirmed a set of 3 underlying factors in both questionnaires that could be interpreted as functional limitation, pain-discomfort, and psychosocial impacts. The model achieved was seen to fit properly for both instruments, but the factorial structure was clearer for the OIDP. Conclusions The results provide evidence for construct equivalence in the latent factors assessed by both OIDP and OHIP-14, suggesting that OHQoL is a three-dimensional construct. The prevalence of impact on these three factors was coherent between both indicators, pain-discomfort having the highest prevalence, followed by psycho-social impact, and functional limitation.

  15. Comparison of Health-Related Quality of Life between children with cerebral palsy and spina bifida.

    Science.gov (United States)

    Tezcan, Sezen; Simsek, Tülay Tarsuslu

    2013-09-01

    This study has two aims-the first is to compare the Health Related Quality of Life (HRQoL) between children with cerebral palsy (CP) and children with spina bifida (SB); the second is to investigate the relationship between HRQoL and age, sex, body mass index (BMI), level of ambulation, cooperation, family income and the mother's education level in both groups of children. The study included 96 children with CP and 70 children with SB (aged 5-18) who attended a physiotherapy and rehabilitation program at an institute of special training and rehabilitation. Socio-demographic information was obtained within the study. The Child Health Questionnaire (CHQ-PF50) was used to evaluate HRQoL. A significant difference was found in terms of age and BMI between children with CP and SB (pself-esteem in children with SB, unlike children with CP. The HRQoL of children with CP was lower than children with SB. The parameters of behavior and parental impact were particularly affected in the children with CP. Minimizing behavioral problems (which can improve with advancing age) of the children with CP and reducing parental impact are important for improving the HRQoL of both the child and parents. There is a need for further studies on this issue. PMID:23787116

  16. Racial Differences in Oral Health-Related Quality of Life: A Multilevel Analysis in Brazilian Children.

    Science.gov (United States)

    Emmanuelli, Bruno; Kucner, Ângela Aniszewski; Ostapiuck, Marjana; Tomazoni, Fernanda; Agostini, Bernardo Antonio; Ardenghi, Thiago Machado

    2015-12-01

    This cross-sectional study aimed to assess the influence of race/ethnicity on Brazilian children' oral health-related quality of life (OHRQoL). A multistage random sampling selected a representative sample of 1,134 twelve-years-old children from public schools of Santa Maria, a city in Southern Brazil. Participants were examined by 4 calibrated clinicians (minimum Kappa-value for inter-examiner agreement of 0.8) and the Brazilian short version of the Child Perceptions Questionnaire (CPQ11-14) was administered. The children's parents or guardians answered questions regarding their demographics and socioeconomic status. Associations were analyzed using multilevel Poisson regression models. Children from racial/ethnic minority groups had poorer OHRQoL. The mean CPQ11-14 score was 1.08 times higher for non-white children than their white counterparts' score. "Social" and "Emotional well-being" were the most affected domains for non-white children, with significantly higher mean scores as compared to white children (RR 1.19, 95% CI, 1.07-1.33; and RR 1.14; 95% CI 1.04-1.24). This association remained significant even after adjusting for individual and contextual covariates. OHRQoL disparities are prevalent among children from racial/ethnic minority groups. Non-white children have lower OHRQoL compared to white children. PMID:26963218

  17. Health-related quality of life in psoriasis: important role of personal resources.

    Science.gov (United States)

    Miniszewska, Joanna; Juczyński, Zygfryd; Ograczyk, Alicja; Zalewska, Anna

    2013-09-01

    Many patients with psoriasis demonstrate psychological disturbances, including decreased health-related quality of life (HRQoL). The aim of this study was to evaluate selected personal resources and HRQoL in 168 in-patients with psoriasis vulgaris. The following questionnaires were used: Skindex-29, General Health Questionnaire, Coping with Skin Disease Scale, Acceptance of Illness Scale, Life Orientation Test, Multidimensional Health Locus of Control Scale and General Self-Efficacy Scale. It was demonstrated that younger patients experienced fewer problems in psychosocial functioning, and that they showed a correlation between worse HRQoL and both external powerful others and external chance domains in locus of health control. Subjective self-evaluation of health correlated with HRQoL irrespective of patient's age. Coping with stress strategies hopelessness/helplessness and distraction/catastrophization correlated with worse overall HRQoL, whereas fighting spirit strategy correlated with better overall HRQoL. Hopelessness/helplessness coping strategy, somatic symptoms, disease acceptance, psoriasis severity and patient's age explained 61% of overall HRQoL variance. Psychomedical interventions designed for psoriatic patients should take into account the above variables. PMID:23407910

  18. Dental status and oral health-related quality of life. A population-based study.

    Science.gov (United States)

    Visscher, C M; Lobbezoo, F; Schuller, A A

    2014-06-01

    Oral health-related quality of life (OHRQoL) is associated with tooth wear and tooth loss. This study investigated the association between OHRQoL and dental status (in terms of natural dentition, partial or complete dentures, or edentulism). Sixteen hundred and twenty-two persons who participated in a large-scale Dutch dental survey were interviewed. Dentate persons (n = 1407) were additionally invited for a clinical examination (response rate: 69%). Dental status was based upon the combined data from this clinical examination and the questionnaire (seven dental status groups were defined). OHRQoL was measured by the Dutch translation of the short version of the Oral Health Impact Profile, the OHIP-NL14. Kruskal-Wallis tests and Mann-Whitney U tests were used to investigate differences in OHRQoL between the dental status groups. For all OHIP-NL14 scales, differences in OHRQoL were found between the dental status groups (all P-values edentulous persons with an overdenture had a more impaired OHRQoL than edentulous persons with non-supported complete dentures. The results demonstrated that impaired dental status is associated with deteriorations in OHRQoL, especially concerning functional limitations, physical pain and social disability. PMID:24698541

  19. Oral health-related quality of life in Swedish young adults

    Directory of Open Access Journals (Sweden)

    Gunvi Johansson

    2015-06-01

    Full Text Available The living conditions of young adults in Sweden have changed during the last decades due to the economic and employment situation in society. Although oral health is mainly considered to be good in this age group, their use of dental care has decreased and their priorities and opportunities regarding oral health are little known. The purpose of this study was to describe the views of Swedish young adults on their oral health and oral health-related quality of life (OHRQoL. The design of the study was qualitative, using content analysis. Sixteen young adults, aged 21–29 years, were interviewed. The findings from the interviews were summarized under the theme “Young adults reflected on their OHRQoL in a time perspective” consisting of three categories: “Past experiences, Present situation, and Future prospects.” The OHRQoL of young adults is dependent not only on their own experiences of oral health during childhood and their received dental care but also on their present self-perceived oral health, oral health habits, and social life; together with their expectations of future oral health. The findings in this study indicate that the oral health awareness and needs of young adults, as well as their expectations of oral care, merit further follow-up.

  20. Health Evaluation for Hypertensive Population Using Exercise Testing and Health-related Quality of Life Questionnaire

    Institute of Scientific and Technical Information of China (English)

    2007-01-01

    Objectives This study aims to assess the impacts of hypertension on health-related quality of life (HRQOL), as well as cardiovascular functional status (CVFS). Methods An instrument was presented based on WHOQOL-BREF and SP-16 questionnaire and exercise testing. 57 normotensive and 76 hypertensive subjects aged 35-65 year-old participated the health survey using this instrument.Based on the exercise testing results of the two groups, a discriminate function was established and used to investigate cardiovascular risk factors for hypertensive population. Results The results showed that persons with hypertension rated significantly lower scores on physical health (i.e. limitation in performing daily activities and problems with work or mobility) than did normotensives (P < 0.01). The discriminant score obtained from the exercise testing results was capable of reflecting the impacts of hypertension on CVFS. Conclusions The method presented in this paper provides a more powerful tool to estimate the effects of health interventions and medical therapy for hypertensive population than just self-rated HRQOL questionnaire.

  1. Pregnancy and health-related quality of life: A cross sectional study

    Directory of Open Access Journals (Sweden)

    Robinson Ramírez-Vélez

    2011-11-01

    Full Text Available Objective: To evaluate and identify determinants of health related quality of life (HRQoL during pregnancy.Methods: In this descriptive exploratory study in sixty-four nulliparous pregnant women, completed the questionnaire:HRQoL (Colombian standard version of the Medical Outcome Study Short-Form Health Survey -SF12v2-, and sociodemographicdeterminants (i.e., age, place of origin, education, marital status, and occupation during the second trimester.Results: Mean age of patients included was 19.1±2.7 years old and gestational age was 17.6 ± 3.4 weeks. The participantsreported higher HRQoL scores in the vitality domain (56±11, followed by mental health (5110, and general health (50±11.Moreover, the lowest score was demonstrated in the domains of emotional role (18±5 and physical role (25±4. Having ahigher household socioeconomic level was significantly correlated with higher scores in the physical role, general health,social functioning, emotional role, and mental health. Being married or cohabiting was significantly correlated with all theSF-12v2 domains, with the exception of the Bodily pain domain.Conclusions: While we have included a comprehensive assessment of socioeconomic variables needed to assess andidentify the factors determining the HRQoL during pregnancy, further studies are needed that can guide the expectations ofwomen, their health care providers, and public policy.

  2. Is low back pain associated with worse health-related quality of life 6 months later?

    DEFF Research Database (Denmark)

    Nolet, P. S.; Kristman, V. L.; Cote, P.; Carroll, L. J.; Cassidy, J.

    2015-01-01

    The purpose of this study was to investigate the impact of low back pain (LBP) on future health-related quality of life (HRQoL). Current evidence suggests that individuals with LBP have poorer HRQoL than those without LBP. However, most of the evidence comes from cross-sectional studies where LBP......, income, arthritis, neck pain, and kidney disorders: grade III-IV LBP (beta = -10.23; 95 % CI -12.46, -7.99), grade II LBP (beta = -6.72, 95 % CI -8.79, -4.65), and grade I LBP (beta = -1.77; 95 % CI -3.18, -0.36). There was no dose-response relationship between LBP and mental HRQoL at 6 months. Low back...... control of known confounders. We formed a cohort of 1,110 randomly sampled Saskatchewan adults in September 1995. LBP at baseline was measured with the chronic pain questionnaire. The SF-36 questionnaire was used to measure physical and mental HRQoL at 6 months follow-up. Multivariable linear regression...

  3. Association of obstructive sleep apnea severity with exercise capacity and health-related quality of life

    Directory of Open Access Journals (Sweden)

    Katrina L Butner

    2013-01-01

    Full Text Available Background: Current research is inconclusive as to whether obstructive sleep apnea severity directly limits exercise capacity and lowers health-related quality of life (HRQoL. Aims: The aim of this study was to evaluate the association of obstructive sleep apnea severity with determinants of exercise capacity and HRQoL. Subjects and Methods: Subjects were evaluated by home somnography and classified as no obstructive sleep apnea ( n = 43 or as having mild ( n = 27, moderate or severe obstructive sleep apnea ( n = 21. Exercise capacity was assessed by a ramping cycle ergometer test, and HRQoL was assessed with the SF-36 questionnaire. Results: Greater obstructive sleep apnea severity was associated with older age, higher body weight, higher body mass index, lower peak aerobic capacity, a higher percentage of peak aerobic capacity at a submaximal exercise intensity of 55 watts, and lower physical component summary score from the SF-36. None of these variables were statistically different among obstructive sleep apnea severity groups after controlling for age and body weight. Obstructive sleep apnea severity was not associated with any cardiorespiratory fitness or HRQoL parameter. Conclusions: Obstructive sleep apnea severity has no independent association with exercise capacity or HRQoL.

  4. Health-related quality of life in children with heart failure as perceived by children and parents.

    Science.gov (United States)

    Wilmot, Ivan; Cephus, Constance E; Cassedy, Amy; Kudel, Ian; Marino, Bradley S; Jefferies, John L

    2016-06-01

    Advancements in paediatric heart failure management have resulted in improved survival and a focus on long-term outcomes including health-related quality of life. We compared health-related quality of life in children with heart failure with healthy patients, children with chronic conditions, and children with cardiovascular disease. Families (n=63) and children (n=73) aged 2-20 years with heart failure were enrolled and compared with data previously published for healthy patients (n=5480), those with chronic conditions (n=247), and those with cardiovascular disease (n=347). Patients and parents completed the PedsQL 4.0 and the Cardiac 3.0 Module health-related quality-of-life questionnaires. PedsQL scores including Total, Psychosocial Health Summary, and Physical were compared between groups. In general, patients with heart failure had lower scores than the healthy population (p=0.001), and comparable scores with those with chronic conditions. Parents perceived no difference in physical scores for children with heart failure when compared with healthy children, and perceived higher scores for children with heart failure when compared with those with chronic conditions (p⩽0.003). Furthermore, children with heart failure had decremental health-related quality-of-life scores as the American Heart Association stage of heart failure increased, such that patients with stage C heart failure had scores similar to children with severe cardiovascular disease. Children with heart failure reported significantly impaired health-related quality of life compared with healthy children and similar scores compared with children with chronic conditions. Parental perceptions appear to underestimate these impairments. Children with heart failure appear to have progressive impairment of health-related quality of life with advancing stage of heart failure. PMID:26277874

  5. Health-related quality of life among osteoarthritis patients attending primary care clinics of Mangalore city

    Directory of Open Access Journals (Sweden)

    HN Harsha Kumar

    2015-01-01

    Full Text Available Introduction: Osteoarthritis (OA of the knee is the most common type of arthritis of the elderly among Asians. Reports suggest that it affects the quality of life. Hence, this study was undertaken with the objective to know the impact of OA of the knee on 8 domains of health related quality of life (HRQoL which include: (1 Physical functioning (PF, (2 role limitation due to physical health (RP. (3 Emotional well-being/mental health (MH, (4 role limitation due to emotional problems (RE, (5 energy/vitality, (6 social well-being (short form [SF], (7 body pain, (8 general health. Materials and Methods: This cross-sectional study was conducted in primary care rural clinics situated on peripheral areas of Mangalore city. Total sample size was calculated to be 77. Patients who met the criteria of modified American Rheumatologic Association Classification for OA of knee were administered a SF-36 questionnaire to measure the HRQoL in the local language version. Mean scores (with its standard deviation across each domain was calculated. Results: Of 80 patients, 38 were males. OA affected HRQoL. Four out 8 factors had more impact on HRQoL (they are PF, RP, MH, RE. Duration of OA is an important determinant on HRQoL. Patients with newer onset of OA (4 years of OA (Domain, Mean, the emotional impact (MH, 44.67; RE, 45.67 reduced but the physical impact (PF, 47.83; RP, 19.75 persisted/got worse. Conclusion: Osteoarthritis had impact on HRQoL. Duration of OA determines the kind of impact. With the onset of OA emotional/mental support would be needed in addition to the medical treatment. As the disease progresses, they tend to cope with emotional/mental problems even as the physical problems persist/increase.

  6. Validation of the nausea and vomiting of pregnancy specific health related quality of life questionnaire

    Science.gov (United States)

    Lacasse, Anaïs; Bérard, Anick

    2008-01-01

    Background The only existing NVP-specific quality of life (QOL) questionnaire is the "Health-Related Quality of Life for Nausea and Vomiting during Pregnancy" (NVPQOL). However, the reliability and validity of the NVPQOL have never been established. In order to justify its usage, the internal consistency and criterion validity of the NVPQOL questionnaire must be ascertained. Methods A prospective observational study including pregnant women attending CHU Sainte-Justine or René-Laennec clinics for their prenatal care was conducted from 2004 to 2006. Women were eligible if they were ≥ 18 years of age and ≤ 16 weeks of gestation at the time of their first prenatal visit. During this initial visit, women who reported NVP were also asked to complete the NVPQOL and the SF-12. Cronbach's alpha coefficients were calculated as the measures of the internal consistency of the NVPQOL. With respect to the criterion validity, linear regression models were built to measure the association between the NVPQOL and the SF-12 scores. Results Of the 367 women included in the study, 288 (78.5%) reported NVP in the first trimester of pregnancy. Among these women, the Cronbach's alpha coefficients were high for the complete NVPQOL questionnaire (α = 0.98), and for the four distinct domains [physical symptoms and aggravating factors (α = 0.90); fatigue (α = 0.94); emotions (α = 0.86); limitations (α = 0.97)]. NVP-specific QOL as measured by the NVPQOL was significantly associated with physical and mental QOL as measured by the SF-12. Conclusion Our data suggest that the NVPQOL is a reliable and valid index to measure NVP-specific QOL in the first trimester of pregnancy. PMID:18471301

  7. Validation of the nausea and vomiting of pregnancy specific health related quality of life questionnaire

    Directory of Open Access Journals (Sweden)

    Lacasse Anaïs

    2008-05-01

    Full Text Available Abstract Background The only existing NVP-specific quality of life (QOL questionnaire is the "Health-Related Quality of Life for Nausea and Vomiting during Pregnancy" (NVPQOL. However, the reliability and validity of the NVPQOL have never been established. In order to justify its usage, the internal consistency and criterion validity of the NVPQOL questionnaire must be ascertained. Methods A prospective observational study including pregnant women attending CHU Sainte-Justine or René-Laennec clinics for their prenatal care was conducted from 2004 to 2006. Women were eligible if they were ≥ 18 years of age and ≤ 16 weeks of gestation at the time of their first prenatal visit. During this initial visit, women who reported NVP were also asked to complete the NVPQOL and the SF-12. Cronbach's alpha coefficients were calculated as the measures of the internal consistency of the NVPQOL. With respect to the criterion validity, linear regression models were built to measure the association between the NVPQOL and the SF-12 scores. Results Of the 367 women included in the study, 288 (78.5% reported NVP in the first trimester of pregnancy. Among these women, the Cronbach's alpha coefficients were high for the complete NVPQOL questionnaire (α = 0.98, and for the four distinct domains [physical symptoms and aggravating factors (α = 0.90; fatigue (α = 0.94; emotions (α = 0.86; limitations (α = 0.97]. NVP-specific QOL as measured by the NVPQOL was significantly associated with physical and mental QOL as measured by the SF-12. Conclusion Our data suggest that the NVPQOL is a reliable and valid index to measure NVP-specific QOL in the first trimester of pregnancy.

  8. Health-related quality of life in patients with dual diagnosis: clinical correlates

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    Benaiges Irina

    2012-09-01

    Full Text Available Abstract Background Although the studies published so far have found an affectation in the Health Related Quality of Life (HRQOL in both psychiatric and substance use dependence disorders, very few studies have applied HRQOL as an assessment measure in patients suffering both comorbid conditions, or Dual Diagnosis. The aim of the current study was to assess HRQOL in a group of patients with Dual Diagnosis compared to two other non-comorbid groups and to determine what clinical factors are related to HRQOL. Methods Cross-sectional assessment of three experimental groups was made through the Short Form – 36 Item Health Survey (SF-36. The sample consisted of a group with Dual Diagnosis (DD; N = 35, one with Severe Mental Illness alone (SMI; N = 35 and another one with Substance Use Dependence alone (SUD; N = 35. The sample was composed only by males. To assess the clinical correlates of SF-36 HRQOL, lineal regression analyses were carried out. Results The DD group showed lower scores in most of the subscales, and in the mental health domain. The group with SUD showed in general a better state in the HRQOL while the group with SMI held an intermediate position with respect to the other two groups. Daily medication, suicidal attempts and daily number of coffees were significantly associated to HRQOL, especially in the DD group. Conclusions The DD group showed lower self-reported mental health quality of life. Assessment of HRQOL in dual patients allows to identify specific needs in this population, and may help to establish therapeutic goals to improve interventions.

  9. Health-related quality of life in high-grade glioma patients

    Institute of Scientific and Technical Information of China (English)

    Linda Dirven; Neil K. Aaronson; Jan J. Heimans; Martin J.B. Taphoorn

    2014-01-01

    Gliomas are malignant primary brain tumors and yet incurable. Palliation and the maintenance or improvement of the patient's quality of life is therefore of main importance. For that reason, health-related quality of life (HRQoL) has become an important outcome measure in clinical trials, next to traditional outcome measures such as overal and progression-free survivals, and radiological response to treatment. HRQoL is a multidimensional concept covering physical, psychological, and social domains, as well as symptoms induced by the disease and its treatment. HRQoL is assessed by using self-reported, validated questionnaires. Various generic HRQoL questionnaires, which can be supplemented with a brain tumor-specific module, are available. Both the tumor and its treatment can have a negative effect on HRQoL. However, treatment with surgery, radiotherapy, chemotherapy, and supportive treatment may also improve patients’ HRQoL, in addition to extending survival. It is expected that the impact of HRQoL measurements in both clinical trials and clinical practice wil increase. Hence, it is important that HRQoL data are col ected, analyzed, and interpreted correctly. Methodological issues such as selection bias and missing data may hamper the interpretation of HRQoL data and should therefore be accounted. In clinical trials, HRQoL can be used to assess the benefits of a new treatment strategy, which should be weighed careful y against the adverse effects of that treatment. In daily clinical practice, HRQoL assessments of an individual patient can be used to inform physicians about the impact of a specific treatment strategy, and it may facilitate the communication between the physicians and the patients.

  10. Long-term health-related quality of life for disease-free esophageal cancer patients.

    LENUS (Irish Health Repository)

    Donohoe, Claire L

    2012-02-01

    BACKGROUND: Health-related quality of life (HRQL) has been studied extensively during the first year following esophagectomy, but little is known about HRQL in long-term survivors. The aim of this study was to investigate HRQL in patients alive at least 1 year after surgical resection for esophageal cancer using validated European Organisation for Research and Treatment of Cancer (EORTC) quality of life (QOL) questionnaires (QLQ). METHODS: Eligible patients, without known disease recurrence and at least 1 year after esophagectomy, were identified from a prospectively maintained database. Patients completed general (QLQ-C30) and esophageal cancer-specific (QLQ-OES18, OG25) questionnaires. A numeric score (0-100) was computed in each conceptual area and compared with validated cancer (n = 1031) and age-matched (n = 7802) healthy populations using two-tailed unpaired t-tests. A cohort of 80 patients had pretreatment scores recorded. RESULTS: Altogether, 132 of 156 eligible patients (84%) completed the self-rated questionnaire, 105 (67.3%) were men, and the mean age was 62 years (range 29-84 years). The mean time since esophagectomy was 70.3 months (12-299 months). Global health status was significantly reduced at least 1 year after esophagectomy (mean +\\/- SD score 48.4 +\\/- 18.6) when compared with patients with esophageal cancer prior to treatment (55.6 +\\/- 24.1) and the general population (71.2 +\\/- 22.4) (p < 0.0001). In a prospective cohort of eighty patients, symptoms related to swallowing difficulty, reflux, pain, and coughing significantly decreased in the long term (p < 0.0001). The degree of subjective swallowing dysfunction was highly correlated with a poor QOL (Spearman\\'s rho = 0.508, p < 0.01). CONCLUSIONS: Global health status remains significantly reduced in long-term survivors after esophagectomy compared with population controls, and swallowing dysfunction is highly associated with this compromised QOL.

  11. Impact of Burden of Thalassemia Major on Health-related Quality of Life in Omani Children.

    Science.gov (United States)

    Mevada, Surekha T; Al Saadoon, Muna; Zachariah, Mathew; Al Rawas, Abdul H; Wali, Yasser

    2016-07-01

    To improve treatment outcome in young patients with homozygous β-thalassemia, evaluation of factors associated with health-related quality of life (HRQoL) is essential to develop clinical, counseling, social, and school support programs. This study was performed to evaluate HRQoL in Omani children with thalassemia who have not been previously evaluated. All patients with thalassemia (5 to 18 y) on regular hypertransfusion from August 2013 to February 2014 were included. Demographic-clinical information was obtained from electronic patient records. The 23-item Pediatric Quality of Life Inventory (PedsQL) 4.0 with 4 multidimensional scales and 3 summary scores was used to assess HRQoL by both patients and caregivers. Statistical analysis was performed using SPSS version 19. Delayed age at diagnosis and delayed initiation of chelation were independently associated with a negative impact on total PedsQL scores; children with higher pretransfusion hemoglobin and lower serum ferritin levels scored better overall. Patients self-rated their HRQoL scores lower as compared with caregivers. Although physical health was more affected than psychosocial health function from both patients' (72.26±22.34 vs. 74.55±18.25) and caregivers' (69.91±19.86 vs. 78.83±18.45) perspective, school functioning domain (68.05±21.30 and 69.71±18.96) scored the lowest. Low ratings for physical health and school functioning highlight the importance of adequate transfusion together with the need for a multidisciplinary teamwork by health care providers, social workers, counselors, family members, and school authorities to provide psychosocial support to prevent mental issues and improve academic performance in these young patients. PMID:27164523

  12. Clinical and psychological correlates of health-related quality of life in obese patients

    Directory of Open Access Journals (Sweden)

    Mannucci Edoardo

    2010-08-01

    Full Text Available Abstract Background Health-related quality of life (HRQL is poor in obese subjects and is a relevant outcome in intervention studies. We aimed to determine factors associated with poor HRQL in obese patients seeking weight loss in medical units, outside specific research projects. Methods HRQL, together with a number of demographic and clinical parameters, was studied with generic (SF-36, PGWB and disease-specific (ORWELL-97 questionnaires in an unselected sample of 1,886 (1,494 women; 392 men obese (BMI > 30 kg/m2 patients aged 20-65 years attending 25 medical units scattered throughout Italy. The clinics provide weight loss treatment using different programs. General psychopathology (SCL-90 questionnaire, the presence of binge eating (Binge Eating scale, previous weight cycling and somatic comorbidity (Charlson's index were also determined. Scores on SF-36 and PGWB were compared with Italian population norms, and their association with putative determinants of HRQL after adjustment for confounders was assessed through logistic regression analysis. Results HRQL scores were significantly lower in women than in men. A greater impairment of quality of life was observed in relation to increasing BMI class, concurrent psychopathology, associated somatic diseases, binge eating, and weight cycling. In multivariate analysis, psychopathology (presence of previously-diagnosed mental disorders and/or elevated scores on SCL-90 was associated with lower HRQL scores on both psychosocial and somatic domains; somatic diseases and higher BMI, after adjustment for confounders, were associated with impairment of physical domains, while binge eating and weight cycling appeared to affect psychosocial domains only. Conclusions Psychopathological disturbances are the most relevant factors associated with poor HRQL in obese patients, affecting not only psychosocial, but also physical domains, largely independent of the severity of obesity. Psychological

  13. Health-related quality of life in asthma studies. Can we combine data from different countries?

    Science.gov (United States)

    Ståhl, E; Postma, D S; Juniper, E F; Svensson, K; Mear, I; Löfdahl, C-G

    2003-01-01

    The aim was to compare health-related quality of life (HRQL) in patients with asthma from 4 countries, and to investigate the correlations between HRQL and clinical indices.341 patients; 140 (Sweden), 54 (Norway), 65 (the Netherlands) and 82 (Greece) were treated with formoterol fumarate 4.5 microg or with terbutaline sulphate 0.5mg for 12 weeks inhaled 'on demand' via Turbuhaler. The Asthma Quality of Life Questionnaire (AQLQ) and clinical indices were assessed. The mean baseline AQLQ overall scores in Sweden (4.97), in the Netherlands (5.04), in Norway (4.68) and in Greece (4.68) were in the same range, however, with a significant difference between the four countries (p=0.038). When comparing AQLQ, activity limitation and symptoms domains, the differences between the countries were not statistically significant. The cross-sectional correlations between AQLQ overall score and the clinical indices were similar in all four countries. The magnitude of change in AQLQ was consistent with the other clinical variables. The correlations between change in AQLQ overall score and change in clinical indices were low to medium in all countries. In conclusion, the consistency of cross-sectional correlations between the AQLQ overall and clinical indices across countries supports the validity of translations of the AQLQ used in this study. There were differences in baseline values between the countries. The treatment response in AQLQ differed to the same extent as other clinical indices. When combining HRQL data from different countries, there might be cultural, gender and socio-economic differences, explaining different responses to treatment. PMID:12657500

  14. Health related quality of life among adolescents with sickle cell disease in Saudi Arabia

    Directory of Open Access Journals (Sweden)

    Mostafa Abdel-Monhem Amr

    2011-02-01

    Full Text Available INTRODUCTION: Increased life expectancy due to recent medical advances has increased the need to understand more fully the quality of life (QoL in patients with sickle cell disease (SCD and factors predicting disease adaptation .The objectives of this study were to assess the impairment of health related quality of life (HRQoL domains in a sample of Saudi Arabian adolescents with SCD. METHODS: A non-probability sample composed of Saudi adolescents with SCD (n=180 aged 14-18 years and comparable age and gender matched healthy controls (n=202. Socio-demographics and disease related data were obtained through personal interview with parents/legal guardians and reviewing patients medical records. Self-administered "Short Form-36" questionnaire was used to assess HRQoL of the included groups. RESULTS: HRQoL showed significant deterioration in adolescents with SCD especially in role physical, general health, and bodily pain domains irrespective of the gender, while female adolescents with SCD demonstrated significant deterioration in emotional wellbeing. Those with SCD-complications showed worse scores along the physical, general health, and emotional wellbeing domains. HRQol scores were negatively associated with increasing age, female gender, rural residence, low family income, presence of disease-related complications and frequent hospital admissions as revealed by multivariate regression analysis. CONCLUSION: Saudi adolescents with SCD experience deterioration along all domains of HRQoL especially the physical. Disease related complications and socio-demographic correlates are significant determinants to worse HRQoL among the included adolescents with SCD.

  15. Does health-related quality of life ‎predict injury event?‎

    Directory of Open Access Journals (Sweden)

    Kambiz Abachizadeh

    2009-07-01

    Full Text Available Background: Unintentional injury is a leading threat to children's health. Some human ‎factors have been determined as predictor of unintentional injury. Association ‎between Health-Related Quality of Life (HRQOL as a human factor and unintentional ‎injuries is unclear. The objective of study is to examine the association between ‎HRQOL and unintentional injuries among primary school children. Methods: This study was a cross-sectional conducted in Ahwaz, a city in Iran. ‎Overall, 3375 children aged 6-10 years were randomly selected from primary school. ‎HRQOL was measured by 56 items taken from seven domains of Netherlands ‎Organization for Applied Scientific Research Academic Medical Center (TNO AZL ‎child quality of life (TACQOL parent form. Parents were interviewed to collect ‎information about incidence, cause and a brief description of injury within the past 12 ‎months prior to the study.‎ Results: The response rate was 3375 of 3792 (89%. There was a significant trend ‎for increasing occurrence of injury with decreasing of HRQOL score (P= Sig. ‎Adjusted OR for injury was significantly higher in very low (2.38, 95% CI: 1.45-‎‎3.86, low (2.18, 95% CI: 1.34-3.56, and medium (1.73, 95%CI: 1.06-2.83 ‎HRQOL groups compared to reference group (very high HRQOL. The median of total ‎HRQOL (P= Sig and all its domains (P=0.017 (except autonomous functioning ‎was lower in injured group compared to uninjured one.‎ Conclusions: This study found an association between HRQOL and unintentional ‎injury among primary school children. This is a preliminary finding and further ‎investigations with a well-defined analytical design are needed.‎

  16. Health-related quality of life of Southern Chinese with chronic hepatitis B infection

    Directory of Open Access Journals (Sweden)

    Lam Elegance TP

    2009-06-01

    Full Text Available Abstract Background Few studies have evaluated the health-related quality of life (HRQOL of Southern Chinese with chronic hepatitis B (CHB infection. Aim To evaluate the HRQOL of Chinese patients at different stages of CHB infection and to find out factors associated with HRQOL. Methods 520 Chinese adult CHB patients of whom 156 were uncomplicated, 102 had impaired liver function, 139 had cirrhosis and 123 had hepatocellular carcinoma (HCC were interviewed with a structured questionnaire, the SF-36 Health Survey version 2 (SF-36v2, and the Chronic Liver Disease Questionnaire (CLDQ. The differences in SF-6D health preference values and SF-36v2 scores between each CHB group and Hong Kong population norms were assessed by t-test. ANOVA was used to compare the mean SF-6D health preference, SF-36v2 scores, and CLDQ scores among CHB groups. Multiple linear regressions were performed to identify determinants of HRQOL. Results CHB patients had significantly lower SF-36v2 scores than the population norm. The SF-6D values of CHB patients with uncomplicated disease, impaired liver function, HCC and cirrhosis were 0.755, 0.745, 0.720 and 0.701, respectively, all significantly lower than the population norm of 0.787. Advanced stage of CHB illness, anti-viral treatment, bilirubin level, psychological co-morbidity, younger age and female were associated with poorer HRQOL. Conclusion CHB infection had a negative impact on HRQOL. There was a progressive decrease in health preference values with CHB disease progression. The results can be used for the estimation of quality adjusted life years (QALYs for CHB patients in cost effectiveness or cost utility studies. Trial Registration http://www.hkclinicaltrials.com; HKCTR-151.

  17. Exploring health-related quality of life in eating disorders by a cross-sectional study and a comprehensive review

    OpenAIRE

    Baiano, Monica; Salvo, Pierandrea; Righetti, Pierluigi; Cereser, Lucia; Baldissera, Erika; Camponogara, Ilenia; Balestrieri, Matteo

    2014-01-01

    Background People with eating disorders (ED) often report poor health-related quality of life (HRQoL), which is explicitly correlated to illness’ severity and its effects on cognitive performance. We aimed to analyze health-related quality of life (HRQoL) in subgroups of eating disorder (ED) patients by using the brief version of WHOQoL questionnaire (WHOQoL-BREF) before treatment administration. Moreover, in order to compare our findings with other published data, we carried out a comprehens...

  18. Long-lasting aquatic exercise therapy improves health-related quality of life and muscle strength in women with fibromyalgia

    OpenAIRE

    Tomas-Carus, Pablo; Gusi, Narcis; Häkkinen, Arja; Häkkinen, Keijo; Raimundo, Armando; Ortega-Alonso, Alfredo

    2007-01-01

    Introduction: Patients with fibromyalgia (FM) present muscle pain, weakness and fatigue that may eventually lead to reduced physical activity and decreased health-related quality of life. The purpose of the present study was to evaluate the effects of 8 months of supervised exercise therapy in warm water on health-related quality of life and muscle strength in women with fibromyalgia. Methods: Thirty women with fibromyalgia [mean ± SD] age 50.8 ± 8.7 (years); body mass index 27.7 ± 4.1 (kg...

  19. Health related quality of life measure in systemic pediatric rheumatic diseases and its translation to different languages

    DEFF Research Database (Denmark)

    Moorthy, Lakshmi Nandini; Roy, Elizabeth; Kurra, Vamsi;

    2014-01-01

    BACKGROUND: Rheumatic diseases in children are associated with significant morbidity and poor health-related quality of life (HRQOL). There is no health-related quality of life (HRQOL) scale available specifically for children with less common rheumatic diseases. These diseases share several......, Hungarian, Japanese, Romanian, Serbian and Xhosa. CONCLUSION: SMILY©-Illness is a brief, easy to administer and score HRQOL scale for children with systemic rheumatic diseases. It is suitable for use across different age groups and literacy levels. SMILY©-Illness with its available translations may be used...

  20. Body checking and avoidance in women: associations with mental and physical health-related quality of life.

    Science.gov (United States)

    Latner, Janet D; Mond, Jonathan M; Vallance, Joanna K; Gleaves, David H; Buckett, Geoffrey

    2012-12-01

    Body checking and body avoidance have demonstrated clinical significance in a number of populations. However, the associations between these behaviors and mental and physical health-related quality of life have not been examined. This study investigated the associations between body checking and avoidance and quality of life in 214 community women. Body checking and body avoidance were significantly correlated with mental and physical quality of life, as well as with eating disturbances. Frequency of body checking significantly predicted impairment in mental quality of life, and frequency of body avoidance significantly predicted impairment in physical quality of life, over and above the contributions of depressive symptoms and related demographic characteristics. Targeting checking and avoidance in prevention and treatment programs may improve quality of life and reduce health-related functional impairment. PMID:23121794

  1. The impact of Irritable Bowel Syndrome on health-related quality of life: a Singapore perspective

    Directory of Open Access Journals (Sweden)

    Wang Yu

    2012-08-01

    Full Text Available Abstract Background Irritable bowel syndrome (IBS is a common gastrointestinal disorder. The prevalence of IBS in Asian countries varies from 2.9% to 15.6%. IBS does not result in increased mortality, but is associated with psychological distress and disruption of work and sleep. Consequently, the evaluation of health-related quality of life (HRQoL is an important outcome measure for patients with IBS since it provides a holistic assessment of the patient's emotional, social and physical function. However, some HRQoL tools can be time-consuming to apply. EQ-5D is a brief HRQoL tool which has been validated in the Western IBS population but has thus far not been used in Asia. This study was conducted to determine whether persons with self-reported symptoms that met the Rome III criteria for IBS had a poorer quality of life than those without these symptoms. We also aimed to determine which specific aspects of quality of life were most affected and whether any risk factors distinguished those with and without IBS. Methods Self-administered questionnaires which included the Rome III diagnostic questionnaire modules for IBS and the EQ-5D questionnaire were obtained from participants of a health symposium in Singapore on 31th October 2010. IBS was diagnosed based on the Rome III Criteria. The main outcome measure was the EQ-5D index score. The relationship between the presence of IBS and the EQ-5D index score, individual dimensions of EQ-5D and demographic risk factors were examined. Results 449 completed questionnaires were analyzed. The mean EQ-5D index score for IBS was 0.739 which was a significant reduction compared to non-IBS participants [−0.11 (95% CI: -0.15 to −0.07, p  Conclusion IBS sufferers have significantly poorer quality of life. Assessment of HRQoL in IBS using the EQ-5D should be considered in further studies and routine clinical practice.

  2. Changes in health-related quality of life and clinical implications in Chinese patients with chronic cough

    OpenAIRE

    Ma, Wei; Yu, Li; Wang, Yu; Li, Xin; LÜ, Hanjing; Qiu, Zhongmin

    2009-01-01

    Background Chronic cough has negative effects on quality of life. However, the changes in health-related quality of life and clinical implications remain unclear in Chinese patients with chronic cough. Methods A standard Chinese version of Leicester cough questionnaire (LCQ) was developed by an established translation procedure and its repeatability was assessed in a preliminary study involving 20 untreated patients with stable chronic cough. The quality of life was measured with the Short fo...

  3. Aspects of care among HIV infected patients : Needs, adherence to treatment and health related quality of life

    OpenAIRE

    Cederfjäll, Claes

    2002-01-01

    The HIV disease has many manifestations, some of which may compromise the patient's well- being and quality of life. In addition, the intake of antiretroviral drugs entails inconvenience or discomfort that may degrade the heath related quality of life (HRQOL).The objectives of these studies were to describe health related quality of life among patients, from an outpatient clinic specialised in HIV care, in relation to coping ability and biomedical status and to identify HIV ...

  4. Association Between Health-Related Quality of Life and Being an Immigrant Among Adolescents, and the Role of Socioeconomic and Health-Related Difficulties

    Directory of Open Access Journals (Sweden)

    Michèle Baumann

    2014-01-01

    Full Text Available To develop satisfactorily, adolescents require good health-related quality of life (QOL, including physical health, psychological health, social relationships and living environment. However, for poorly understood reasons, it is often lacking, especially among immigrants with lower family and socioeconomic resources. This study assessed health-related QOL of European and non-European immigrant adolescents and the contributions of socioeconomic difficulties, unhealthy behaviors, and violence. It included 1,559 middle-school adolescents from north-eastern France (mean age 13.5, SD 1.3; 1,451 French adolescents, 54 European immigrants and 54 non-European immigrants, who completed a self-administered questionnaire including sex, age, socioeconomic characteristics (family structure, parents’ education, occupation, and income, unhealthy behaviors (uses of tobacco/alcohol/cannabis/hard drugs, obesity, and involvement in violence, having sustained violence, sexual abuse, and the four QOL domains measured with the World Health Organization’s WHOQOL-BREF (poor: score < 25PthP percentile. Data were analyzed using logistic regression models. Poor physical health, psychological health, social relationships, and living environment affected more European immigrants (26% to 35% and non-European immigrants (43% to 54% than French adolescents (21% to 26%. European immigrants had a higher risk of poor physical health and living environment (gender-age-adjusted odds ratio 2.00 and 1.88, respectively while non-European immigrants had a higher risk for all poor physical health, psychological health, social relationships, and living environment (3.41, 2.07, 3.25, and 3.79, respectively. Between 20% and 58% of these risks were explained by socioeconomic difficulties, parts of which overlapped with unhealthy behaviors and violence. The associations between the two sets of covariates greatly differed among French adolescents and immigrants. Poor QOL was more common

  5. Sleep disturbances and health-related quality of life in adults with steady-state bronchiectasis.

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    Yonghua Gao

    Full Text Available Sleep disturbances are common in patients with chronic lung diseases, but little is known about the prevalence in patients with bronchiectasis. A cross sectional study was conducted to investigate the prevalence and determinants associated with sleep disturbances, and the correlation between sleep disturbances and quality of life (QoL in adults with steady-state bronchiectasis.One hundred and forty-four bronchiectasis patients and eighty healthy subjects were enrolled. Sleep disturbances, daytime sleepiness, and QoL were measured by utilizing the Pittsburgh Sleep Quality Index (PSQI, Epworth Sleepiness Scale (ESS and St. George Respiratory Questionnaire (SGRQ, respectively. Demographic, clinical indices, radiology, spirometry, bacteriology, anxiety and depression were also assessed.Adults with steady-state bronchiectasis had a higher prevalence of sleep disturbances (PSQI>5 (57% vs. 29%, P<0.001, but not daytime sleepiness (ESS≥10 (32% vs. 30%, P = 0.76, compared with healthy subjects. In the multivariate model, determinants associated with sleep disturbances in bronchiectasis patients included depression (OR, 10.09; 95% CI, 3.46-29.37; P<0.001, nocturnal cough (OR, 1.89; 95% CI, 1.13-3.18; P = 0.016, aging (OR, 1.04; 95% CI, 1.01-1.07; P = 0.009 and increased 24-hour sputum volume (OR, 2.01; 95% CI, 1.22-3.33; P = 0.006. Patients with sleep disturbances had more significantly impaired QoL affecting all domains than those without. Only 6.2% of patients reported using a sleep medication at least weekly.In adults with steady-state bronchiectasis, sleep disturbances are more common than in healthy subjects and are related to poorer QoL. Determinants associated with sleep disturbances include depression, aging, nighttime cough and increased sputum volume. Assessment and intervention of sleep disturbances are warranted and may improve QoL.

  6. Health-related quality of life and affective status in liver transplant recipients and patients on the waiting list with low MELD scores

    Science.gov (United States)

    Benzing, Christian; Krezdorn, Nicco; Förster, Julia; Hinz, Andreas; Krenzien, Felix; Atanasov, Georgi; Schmelzle, Moritz; Hau, Hans-Michael; Bartels, Michael

    2016-01-01

    Background This study seeks to examine the impact of orthotopic liver transplantation (OLT) on Health-Related Quality of Life (HRQoL) and mental health in patients with different MELD scores. Methods Patients who has undergone orthotopic liver transplant (OLT) or were on the waiting list for OLT were submitted to HRQoL and depression/anxiety assessment by questionnaire: Short-Form 36 (SF-36), Questions on Life Satisfaction (FLZ-M), Patient Health Questionnaire-4 (PHQ-4). Data were analysed following division of patients into three groups: pretransplant patients with a MELD score <10, ≥10, and OLT recipients. Results The surveys were sent to 940 consecutive patients within one week in June 2013. Of these 940 patients, 869 (92.4%) met the inclusion criteria. In total, 291 (33.5%) eligible questionnaires (OLT group: 235, MELD <10: 25; MELD _10: 31) were suitable for analysis. General health (GH), vitality (VIT), and mental health (MH) were lower in both pretransplant groups compared to the OLT group (all p < 0.05). Anxiety and depression were higher in the MELD <10 group than in the OLT group (anxiety: p < 0.05; depression: p < 0.01). Discussion Patients with low MELD scores seem to benefit from OLT with regards to HRQoL and mental health. PMID:27154809

  7. The relationship between health-related fitness and quality of life in postmenopausal women from Southern Taiwan

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    Hsu WH

    2014-09-01

    Full Text Available Wei-Hsiu Hsu,1–3 Chi-lung Chen,2 Liang Tseng Kuo,2 Chun-Hao Fan,1 Mel S Lee,2 Robert Wen-Wei Hsu2 1Sports Medicine Center, Chang Gung Memorial Hospital at Chia Yi, Chia Yi, Taiwan; 2Division of Sports Medicine, Department of Orthopedic Surgery, Chang Gung Memorial Hospital at Chia Yi, Chia Yi, Taiwan; 3Department of Medicine, Chang Gung University, Tao Yuan, Taiwan Background: Health-related fitness has been reported to be associated with improved quality of life (QoL in the elderly. Health-related fitness is comprised of several dimensions that could be enhanced by specific training regimens. It has remained unclear how various dimensions of health-related fitness interact with QoL in postmenopausal women.Objective: The purpose of the current study was to investigate the relationship between the dimensions of health-related fitness and QoL in elderly women.Methods: A cohort of 408 postmenopausal women in a rural area of Taiwan was prospectively collected. Dimensions of health-related fitness, consisting of muscular strength, balance, cardiorespiratory endurance, flexibility, muscle endurance, and agility, were assessed. QoL was determined using the Short Form Health Survey (SF-36. Differences between age groups (stratified by decades were calculated using a one-way analysis of variance (ANOVA and multiple comparisons using a Scheffé test. A Spearman’s correlation analysis was performed to examine differences between QoL and each dimension of fitness. Multiple linear regression with forced-entry procedure was performed to evaluate the effects of health-related fitness. A P-value of <0.05 was considered statistically significant.Results: Age-related decreases in health-related fitness were shown for sit-ups, back strength, grip strength, side steps, trunk extension, and agility (P<0.05. An age-related decrease in QoL, specifically in physical functioning, role limitation due to physical problems, and physical component score, was also

  8. Measuring health-related quality of life in adolescents and young adults: Swedish normative data for the SF-36 and the HADS, and the influence of age, gender, and method of administration

    OpenAIRE

    von Essen Louise; Wettergen Lena; Jörngården Anna

    2006-01-01

    Abstract Background There is a paucity of research about health-related quality of life (HRQL) among adolescents, as studies have to a large extent focused on adults. The main aim was to provide information for future studies in this growing field by presenting normative data for the Short Form 36 (SF-36) and the Hospital Anxiety and Depression Scale (HADS) for Swedish adolescents and young adults. Additionally, the influence of age and gender, as well as method of administration, was investi...

  9. Health-related quality of life and chronic obstructive pulmonary disease in North Carolina

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    David W. Brown

    2010-02-01

    Full Text Available Background: Comparisons of health-related quality of life (HRQOL between persons with chronic obstructive pulmonary disease (COPD and adults in the general population are not well described. Aims: To examine associations between COPD and four measures of HRQOL in a population-based sample. Patients & Methods: These relationships were examined using data from 13,887 adults aged >18 years who participated in the 2007 Behavioral Risk Factor Surveillance System (BRFSS conducted in North Carolina (NC. Logistic regression was used to obtain adjusted relative odds (aOR. Results: The age-adjusted prevalence of COPD among NC adults was 5.4% (standard error 0.27. Nearly half of adults with COPD reported fair/poor health compared with 15% of those without the condition (age-aOR, 5.5; 95% confidence interval [CI], 4.4 to 6.8. On average, adults with COPD reported twice as many unhealthy days (physical/mental as those without the condition. The age-adjusted prevalence of >14 unhealthy days during the prior 30 days was 45% for adults with COPD and 17% for those without. The aOR of >14 unhealthy days was 1.7 (95% CI, 1.4 to 2.2 times greater among adults with COPD compared with those without. Conclusions: These results suggest COPD is independently associated with lower levels of HRQOL and reinforce the importance of preventing COPD and its complications through health education messages stressing efforts to reduce total personal exposure to tobacco smoke, occupational dusts and chemicals, and other indoor and outdoor air pollutants linked to COPD and early disease recognition. Our findings represent one of the few statewide efforts in the US and provide guidance for disease management and policy decision making.

  10. Impact of canine overweight and obesity on health-related quality of life.

    Science.gov (United States)

    Yam, P S; Butowski, C F; Chitty, J L; Naughton, G; Wiseman-Orr, M L; Parkin, T; Reid, J

    2016-05-01

    Canine obesity is increasing in prevalence in the UK and raises concerns about dog welfare. This study compares the health-related quality of life (HRQL) of dogs of varying body condition: overweight and obese (BCS 4 and 5) versus non-overweight dogs (BCS 2 and 3), obese (BCS 5) versus non-overweight (BCS 2 and 3) and an overall comparison between all four BCS (BCS 2, 3, 4 and 5) using a novel, validated HRQL instrument which is both web and mobile tablet/phone app based. Of 271 dog owners who were approached, 174 completed a web-based instrument (2013) or a mobile tablet app instrument (2014) during the summers of 2013 and 2014. Automatically generated scores in four domains of HRQL (energetic/enthusiastic, happy/content, active/comfortable, calm/relaxed) were compared for dogs with each of the body condition scores (BCS 2-5). For all body condition scores a statistically significant difference was found between the HRQL scores in two of the domains: energetic/enthusiastic (p=0.02) and active comfortable (p=0.004). When BCS 2 and 3 were compared to BCS 4 and 5, statistical significance was found in the same two domains - energetic/enthusiastic (p=0.01) and active comfortable (p=0.001) - as it was in comparison of non-overweight (BCS 2 and 3) compared to obese dogs (BCS 5): energetic/enthusiastic (p=0.012) and active comfortable (p=0.004). These results suggest that overweight and obese dogs have a reduced HRQL in two of the domains compared to non-overweight dogs, and that differences in HRQL are detectable between BCS scores 2, 3, 4 and 5. PMID:27094142

  11. The effect of hepatitis C virus infection on health-related quality of life in prisoners.

    Science.gov (United States)

    Thein, Hla-Hla; Butler, Tony; Krahn, Murray; Rawlinson, William; Levy, Michael H; Kaldor, John M; Dore, Gregory J

    2006-03-01

    Hepatitis C virus (HCV) infection in prisoners represents an important public health problem. However, there is very little information about HCV-related health-related quality of life (HRQOL). We examined the effect of HCV antibody positivity, HCV viremia, and being a prisoner on prisoners'' HRQOL. Population-based health surveys incorporating HCV screening were conducted among prisoners at New South Wales (NSW), Australia, correctional centers in 1996 and 2001. HCV antibody and HCV RNA status were determined from venous blood sampling. HRQOL and mood status were assessed using the Short Form-36 (SF-36) Health Survey and Beck Depression Inventory (BDI). Comparison of HRQOL scores between HCV antibody negative, HCV antibody positive/non-viremic, and HCV antibody positive/viremic and assessment of temporal change in HRQOL between 1996 and 2001 within groups were made using ANCOVA adjusting for confounders. Factors associated with HRQOL were determined in linear regression models. Analyses between HCV antibody negative (n = 423), HCV positive/non-viremic (n = 89), and HCV positive/viremic (n = 178) prisoners found no measurable effect of HCV on HRQOL, including that attributable to HCV viremia. Compared to uninfected Australian population norms, prisoners had lower HRQOL irrespective of HCV status. The prevalence of 'moderate' to 'severe' depressive symptoms was greater in the HCV antibody positive/viremic group than the HCV antibody positive/non-viremic group or the HCV antibody negative group. Selected demographic factors (age), co-morbidity, severity of depressive symptoms and medical care utilization influenced HRQOL. There was evidence to support the effect of knowledge of HCV status on HRQOL. In conclusion, our findings contrast with previous studies in non-prisoner groups in which HCV infection appears to decrease overall HRQOL. Non-HCV factors may override HCV-specific HRQOL impairment in this population. Targeted management strategies are required to improve

  12. Factors related to oral health related quality of life in TMD patients.

    Science.gov (United States)

    Rener-Sitar, Ksenija; Celebić, Asja; Mehulić, Ketij; Petricević, Nikola

    2013-06-01

    The aims of the study were to determine the impact of temporomandibular disorders (TMD) on self-percieved oral health related quality of life (OHRQoL) and to compare OHRQoL of patients with TMD with a control group. A total of 81 TMD patients participated in a study group and 400 adults served as the control group. The mean OHIP summary scores were computed for all patients with the same diagnosis and the same subgroup of axis I according to the RDC/TMD exam form. The mean OHIP subscores for all seven domains of the OHIP questionnaire were compared between the study and the control group. The hierarchical linear regression model was used to assess the most important variables according to the RDC/TMD protocol that contribute to OHRQoL in TMD patients with the OHIP summary score as dependent variable. According to this study, TMD had a high association with reduced OHRQoL (p < 0.001). More diagnoses of axis I according to the RDC/TMD protocol (p < 0.001), higher age of TMD patients (p < 0.001) and diagnoses associated with limited jaw movements contributed to more impaired OHRQoL (p = 0.008 and p = 0.030, respectively). Female TMD patients had no significantly different OHRQoL compared to male patients (p = 0.436). According to regression analysis, higher age (p < 0.001), more physical diagnoses (p = 0.018) and diagnosis Ib (p = 0.169) explained 39.1% of the variability (p < 0.001) of the OHIP summary score in TMD patients. PMID:23940982

  13. Health-related quality of life and depression among medical sales representatives in Pakistan.

    Science.gov (United States)

    Atif, Muhammad; Bashir, Arslan; Saleem, Quratulain; Hussain, Rabia; Scahill, Shane; Babar, Zaheer-Ud-Din

    2016-01-01

    Pharmaceutical companies have been known to pose stress and mental harassment on medical sales representatives (MSRs) in-order to increase pharmaceutical sales. This cross sectional descriptive study, conducted during November and December 2014 in the Lahore and Bahawalpur districts of Punjab, Pakistan, evaluates the Health-Related Quality of Life (HRQoL) and extent of depression among MSRs in Pakistan. The significant predictors of HRQoL and depression among the MSRs were also determined. Using a convenience sampling technique, all consenting MSRs (N = 318) of pharmaceutical companies were asked to self-complete the Short Form-36 (SF-36v2) Health Survey and Stanford Personal Health Questionnaire (PHQ-8). The standard scoring scheme for the SF36v2 and PHQ-8 questionnaires was used. The PHQ-8 scores showed that 16.4 % (n = 52) and 2.5 % of respondents were suffering from major depression and severe major depression, respectively. Being depressed and having difficulty in achieving sales targets were the factors independently associated with lower physical health. Similarly, depression, insufficient time for the family and monthly income less than 36,000 Pakistan Rupees were significant predictors of lower mental health. The factors associated with depression included insufficient time for the family and unsatisfactory behavior of the managers. Compromised mental health and the prevalence of depression among the MSRs suggest pharmaceutical companies need to devise health management strategies and interventions to ensure effective prevention and management of mental health problems among Pakistani MSRs. PMID:27462496

  14. Health-related quality of life in end-stage COPD and lung cancer patients.

    Science.gov (United States)

    Habraken, Jolanda M; ter Riet, Gerben; Gore, Justin M; Greenstone, Michael A; Weersink, Els J M; Bindels, Patrick J E; Willems, Dick L

    2009-06-01

    Historically, palliative care has been developed for cancer patients and is not yet generally available for patients suffering from chronic life-limiting illnesses, such as chronic obstructive pulmonary disease (COPD). To examine whether COPD patients experience similar or worse disease burden in comparison with non-small cell lung cancer (NSCLC) patients, we compared the health-related quality of life (HRQOL) scores of severe COPD patients with those of advanced NSCLC patients. We also formally updated previous evidence in this area provided by a landmark study published by Gore et al. in 2000. In updating this previous evidence, we addressed the methodological limitations of this study and a number of confounding variables. Eighty-two GOLD IV COPD patients and 19 Stage IIIb or IV NSCLC patients completed generic and disease-specific HRQOL questionnaires. We used an individual patient data meta-analysis to integrate the new and existing evidence (total n=201). Finally, to enhance between-group comparability, we performed a sensitivity analysis using a subgroup of patients with a similar degree of "terminality," namely those who had died within one year after study entry. Considerable differences in HRQOL were found for physical functioning, social functioning, mental health, general health perceptions, dyspnea, activities of daily living, and depression. All differences favored the NSCLC patients. The sensitivity analysis, using only terminal NSCLC and COPD patients, confirmed these findings. In conclusion, end-stage COPD patients experience poor HRQOL comparable to or worse than that of advanced NSCLC patients. We discuss these findings in the light of the notion that these COPD patients may have a similar need for palliative care. PMID:19394792

  15. Health-related quality of life and depression in Rett syndrome caregivers

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    Sarajlija Adrijan

    2013-01-01

    Full Text Available Background/Aim. Rett syndrome (RTT is a severe neurodevelopmental disorder primarily affecting females with an estimated incidence of 1 : 10,000-15,000 female births. Currently, there is no specific treatment that halts or reverses the progression of RTT. Therefore, management was mainly symptomatic, focussed on optimising patient's abilities. The aim of this study was to investigate factors influencing health-related quality of life (HRQoL and depression in mothers who care for children with Rett syndrome (RTT in Serbia. Methods. The cross-sectional study was conducted on 49 mothers giving care to females with RTT. Caregivers` HRQoL was assessed by using the SF-36 questionnaire. Clinical severity score (CSS of RTT patients and Beck Depression Inventory II (BDI -II scale were used to quantify RTT severity and mothers` depression, respectively. Statistical assessment included descriptive statistics, ttest, Pearson correlation coefficient and multiple logistic regression. Results. The age of mothers ranged from 22 to 55 years and of their affected children from 3 to 29 years. Severe depression was observed in 15 (30.6% participants. CSS and BDI - II scores correlated negatively with all SF- 36 domains and composite scores. Lowest scoring domains of HRQoL in mothers giving care to RTT children were mental health, vitality and role functioning emotional. Multiple linear regression analysis revealed that severity of RTT patients` disability (CSS and caregivers` age are factors with strongest influence to HRQoL and depression in care giving mothers. Conclusion. Mothers giving care to children with RTT are at high risk of severe depression and lower HRQoL scores of domains that reflect mental well-being. Results of this study can help in planning subsequent interventions directed at families dealing with Rett syndrome.

  16. Health-related quality of life in patients with Chagas disease

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    Bruna Guimarães Oliveira

    2011-04-01

    Full Text Available INTRODUCTION: Chagas disease (ChD is a chronic illness related to significant morbidity and mortality that can affect the quality of life (QoL of infected patients. However, there are few studies regarding QoL in ChD. The objectives of this study are to construct a health-related QoL (HRQoL profile of ChD patients and compare this with a non-ChD (NChD group to identify factors associated with the worst HRQoL scores in ChD patients. METHODS: HRQoL was investigated in 125 patients with ChD and 21 NChD individuals using the Medical Outcomes Study 36-item Short-Form (SF-36 and the Minnesota Living with Heart Failure Questionnaire (MLWHFQ. Patients were submitted to a standard protocol that included clinical examination, ECG, Holter monitoring, Doppler echocardiogram and autonomic function tests. RESULTS: HRQoL scores were significantly worse among the ChD group compared to the NChD group in the SF-36 domains of physical functioning and role-emotional and in the MLWHFQ scale. For the ChD group, univariate analysis showed that HRQoL score quartiles were associated with level of education, sex, marital status, use of medication, functional classification and cardiovascular and gastrointestinal symptoms. In the multivariate analysis, female sex, fewer years of education, single status, worst functional classification, presence of cardiovascular and gastrointestinal symptoms, associated illnesses, Doppler echocardiographic abnormalities and ventricular arrhythmia detected during Holter monitoring were predictors of lower HRQoL scores. CONCLUSIONS: ChD patients showed worse HRQoL scores compared to NChD. For the ChD group, sociodemographic and clinical variables were associated with worst scores.

  17. Validation of a computer-adaptive test to evaluate generic health-related quality of life

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    Zardaín Pilar C

    2010-12-01

    Full Text Available Abstract Background Health Related Quality of Life (HRQoL is a relevant variable in the evaluation of health outcomes. Questionnaires based on Classical Test Theory typically require a large number of items to evaluate HRQoL. Computer Adaptive Testing (CAT can be used to reduce tests length while maintaining and, in some cases, improving accuracy. This study aimed at validating a CAT based on Item Response Theory (IRT for evaluation of generic HRQoL: the CAT-Health instrument. Methods Cross-sectional study of subjects aged over 18 attending Primary Care Centres for any reason. CAT-Health was administered along with the SF-12 Health Survey. Age, gender and a checklist of chronic conditions were also collected. CAT-Health was evaluated considering: 1 feasibility: completion time and test length; 2 content range coverage, Item Exposure Rate (IER and test precision; and 3 construct validity: differences in the CAT-Health scores according to clinical variables and correlations between both questionnaires. Results 396 subjects answered CAT-Health and SF-12, 67.2% females, mean age (SD 48.6 (17.7 years. 36.9% did not report any chronic condition. Median completion time for CAT-Health was 81 seconds (IQ range = 59-118 and it increased with age (p Conclusions Although domain-specific CATs exist for various areas of HRQoL, CAT-Health is one of the first IRT-based CATs designed to evaluate generic HRQoL and it has proven feasible, valid and efficient, when administered to a broad sample of individuals attending primary care settings.

  18. Parents' perception of health-related quality of life in children and adolescents with excess weight

    Directory of Open Access Journals (Sweden)

    Melissa Maria Romero Nascimento

    2016-02-01

    Full Text Available ABSTRACT OBJECTIVE: To evaluate the perception of parents or caregivers on the health-related quality of life (HRQOL of children/adolescents with overweight/obesity and possible factors associated with this perception. METHODS: This was a cross-sectional study involving 297 caregivers of children and adolescents with normal weight (n = 170 and with overweight/obesity (n = 127, from public and private schools in the study municipality. HRQOL scores obtained through the Child Health Questionnaire - Parent Form 50 (CHQ-PF50 were compared according to the nutritional status and gender of the children/adolescents. Multiple regression analysis was used to determine the predictive value of studied variables for the variation in HRQOL scores. RESULTS: Parents of children/adolescents with overweight/obesity attributed lower HRQOL scores to their children in the following domains: physical functioning (p < 0.01; d = 0.49, self-esteem (p < 0.01; d = 0.38, parental impact-emotional (p < 0.05; d= 0.29, family cohesion (p < 0.05; d = 0.26, physical summary score (p < 0.05;d = 0.29, and psychosocial summary score (p < 0.05; d = 0.25. In the multiple regression models, the variables with the highest contribution to the variation in HRQOL scores were: in the physical functioning domain, parental impact-time (ß = 0.23; p < 0.05; self-esteem, nutritional status (ß = -0.18;p ≤ 0.01; emotional impact on parents, impact on parents' time (ß = 0.31; p < 0.05; and in family cohesion, global behavior (ß = 0.30;p < 0.05. CONCLUSIONS: A negative impact on HRQOL of children/adolescents with overweight/obesity was observed in the physical and psychosocial aspects. The nutritional status was the variable with the greatest contribution for the assessment the self-esteem of children and adolescents in this study.

  19. Health related quality of life in pregeriatric patients with chronic diseases at urban, public supported clinics

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    Nguyen Kim M

    2003-10-01

    Full Text Available Abstract Background Understanding health-related quality of life (HRQOL leads to more effective and focused healthcare. America's growing health disparities makes it is increasingly necessary to understand the HRQOL of pregeriatric individuals who are now 55–64 years old, i.e. before they are eligible for federally mandated health care at age 65. Our study measured the self-perceived HRQOL of pregeriatric, poor patients with multiple chronic diseases treated at 2 public clinics. Methods Consecutive patients aged 55–64 years, many with multiple chronic diseases, responded in an interview to the 36-Item Short-Form Health Survey (SF–36 as a general measure of HRQOL during a regular visit to one of two university-staffed urban public clinics. Results The perceived physical and mental functioning of 316 pregeriatric patients was tabulated from SF–36 scores to yield their HRQOL. Their scores were statistically significantly lower than those of the general US pregeriatric population and lower than averages for US patients with multiple chronic diseases. All eight subscale scores of SF–36 were 16% to 36% lower compared with the averages of the general US pregeriatric population. Further, as the number of chronic diseases increased, the lower was the HRQOL. Lower physical and mental scores were associated with a lower income, unemployment, and higher numbers of multiple chronic diseases. Conclusion Chronic diseases have a powerful negative impact on perceived mental and physical functioning in pregeriatric patients. HRQOL information can assist health care providers to gain a more complete picture of their pregeriatric patients' health.

  20. Health-related quality of life of Canadian children and youth prenatally exposed to alcohol

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    Ungar Wendy J

    2006-10-01

    Full Text Available Abstract Background In Canada, the incidence of Fetal Alcohol Spectrum Disorder (FASD has been estimated to be 1 in 100 live births. Caused by prenatal exposure to alcohol, FASD is the leading cause of neuro-developmental disabilities among Canadian children, and youth. Objective: To measure the health-related quality of life (HRQL of Canadian children and youth diagnosed with FASD. Methods A prospective cross-sectional study design was used. One-hundred and twenty-six (126 children and youth diagnosed with FASD, aged 8 to 21 years, living in urban and rural communities throughout Canada participated in the study. Participants completed the Health Utilities Index Mark 3 (HUI3. HUI3 measures eight health attributes: vision, hearing, speech, ambulation, dexterity, emotion, cognition, and pain. Utilities were used to measure a single cardinal value between 0 and 1.0 (0 = all-worst health state; 1 = perfect health to reflect the global HRQL for that child. Mean HRQL scores and range of scores of children and youth with FASD were calculated. A one-sample t-test was used to compare mean HRQL scores of children and youth with FASD to those from the Canadian population. Results Mean HRQL score of children and youth with FASD was 0.47 (95% CI: 0.42 to 0.52 as compared to a mean score of 0.93 (95% CI: 0.92 to 0.94 in those from the general Canadian population (p Conclusion Children and youth with FASD have significantly lower HRQL than children and youth from the general Canadian population. This finding has significant implications for practice, policy development, and research.

  1. Patterns of impaired oral health-related quality of life dimensions.

    Science.gov (United States)

    John, M T; Rener-Sitar, K; Baba, K; Čelebić, A; Larsson, P; Szabo, G; Norton, W E; Reissmann, D R

    2016-07-01

    How dental patients are affected by oral conditions can be described with the concept of oral health-related quality of life (OHRQoL). This concept intends to make the patient experience measurable. OHRQoL is multidimensional, and Oral Function, Oro-facial Pain, Oro-facial Appearance and Psychosocial Impact were suggested as its four dimensions and consequently four scores are needed for comprehensive OHRQoL assessment. When only the presence of dimensional impact is measured, a pattern of affected OHRQoL dimensions would describe in a simple way how oral conditions influence the individual. By determining which patterns of impact on OHRQoL dimensions exist in prosthodontic patients and general population subjects, we aimed to identify in which combinations oral conditions' functional, painful, aesthetical and psychosocial impact occurs. Data came from the Dimensions of OHRQoL Project with Oral Health Impact Profile (OHIP)-49 data from 6349 general population subjects and 2999 prosthodontic patients in the Learning Sample (N = 5173) and the Validation Sample (N = 5022). We hypothesised that all 16 patterns of OHRQoL dimensions should occur in these individuals who suffered mainly from tooth loss, its causes and consequences. A dimension was considered impaired when at least one item in the dimension was affected frequently. The 16 possible patterns of impaired OHRQoL dimensions were found in patients and general population subjects in both Learning and Validation Samples. In a four-dimensional OHRQoL model consisting Oral Function, Oro-facial Pain, Oro-facial Appearance and Psychosocial Impact, oral conditions' impact can occur in any combination of the OHRQoL dimensions. PMID:27027734

  2. Health-related quality of life in patients with Chagas disease: a review of the evidence

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    Giovane Rodrigo Sousa

    2015-04-01

    Full Text Available Chagas disease (ChD, a neglected tropical disease caused by infection with the parasite Trypanosoma cruzi (T. cruzi, remains a serious public health issue in Latin America and is an emerging disease in several non-endemic countries, where knowledge of the condition and experience with its clinical management are limited. Regionally, the disease is the major cause of disability secondary to tropical diseases in young adults. Health-related quality of life (HRQoL impairment is common in patients with ChD, especially in those with Chagas dilated cardiomyopathy, the most severe manifestation of the disease, which frequently leads to heart failure. The aim of this review was to conduct a literature search for studies that have evaluated the determining factors of HRQoL in ChD patients. We included cross-sectional, case-control, cohort, and experimental studies, as well as clinical trials that evaluated the HRQoL in ChD patients aged 18 to 60 years and are presenting an explicit description of statistical analysis. Using a combination of keywords based on Descriptors in Health Sciences (DeCS and Medical Subject Headings (MeSH for searches in PubMed and the Scientific Electronic Library Online (SciELO, 148 studies were found. After exclusions, 12 studies were selected for analysis. Three main findings were extracted from these studies: 1 cardiac involvement is associated with a worse HRQoL in ChD patients; 2 HRQoL is associated with the patients' functional capacity; and 3 simple and inexpensive therapeutic measures are effective for improving HRQoL in ChD patients. Hence, ChD patients' functional capacity, the effectiveness of non-surgical conservative treatment, and cardiac involvement are important determining factors for the HRQoL in ChD patients.

  3. Systematic review of health-related quality of life after esophagectomy for esophageal cancer

    Institute of Scientific and Technical Information of China (English)

    Marco Scarpa; Stefano Valente; Rita Alfieri; Matteo Cagol; Giorgio Diamantis; Ermanno Ancona; Carlo Castoro

    2011-01-01

    This study is aimed to assess the long-term health-related quality of life (HRQL) of patients after esopha gectomy for esophageal cancer in comparison with established norms, and to evaluate changes in HRQL during the different stages of follow-up after esophageal resection. A systematic review was performed by searching medical databases (Medline, Embase and the Cochrane Library) for potentially relevant studies that appeared between January 1975 and March 2011. Studies were included if they addressed the question of HRQL after esophageal resection for esophageal cancer. Two researchers independently performed the study selection, data extraction and analysis processes. Twenty-one observational studies were included with a total of 1282 (12-355) patients. Five studies were performed with short form-36 (SF-36) and 16 with European Organization for Research and Treatment of Cancer (EORTC) QLQ C30 (14 of them also utilized the disease-specific 0ES18 or its previous version OES24).The analysis of long-term generic HRQL with SF-36 showed pooled scores for physical, role and social function after esophagectomy similar to United States norms, but lower pooled scores for physical function, vitality and general health perception. The analysis of HRQL conducted using the Global EORTC C30 global scale during a 6-mo follow-up showed that global scale and physical function were better at the baseline. The symptom scales indicated worsened fatigue, dyspnea and diarrhea 6 mo after esophagectomy. In contrast, however, emotional function had significantly improved after 6 mo. In conclusion, short- and long-term HRQL is deeply affected after esophagectomy for cancer. The impairment of physical function may be a long-term consequence of esophagectomy involving either the respiratory system or the alimentary tract. The short-and long-term improvement in the emotional function of patients who have undergone successful operations may be attributed to the impression that they have

  4. Longitudinal beta regression models for analyzing health-related quality of life scores over time

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    Hunger Matthias

    2012-09-01

    Full Text Available Abstract Background Health-related quality of life (HRQL has become an increasingly important outcome parameter in clinical trials and epidemiological research. HRQL scores are typically bounded at both ends of the scale and often highly skewed. Several regression techniques have been proposed to model such data in cross-sectional studies, however, methods applicable in longitudinal research are less well researched. This study examined the use of beta regression models for analyzing longitudinal HRQL data using two empirical examples with distributional features typically encountered in practice. Methods We used SF-6D utility data from a German older age cohort study and stroke-specific HRQL data from a randomized controlled trial. We described the conceptual differences between mixed and marginal beta regression models and compared both models to the commonly used linear mixed model in terms of overall fit and predictive accuracy. Results At any measurement time, the beta distribution fitted the SF-6D utility data and stroke-specific HRQL data better than the normal distribution. The mixed beta model showed better likelihood-based fit statistics than the linear mixed model and respected the boundedness of the outcome variable. However, it tended to underestimate the true mean at the upper part of the distribution. Adjusted group means from marginal beta model and linear mixed model were nearly identical but differences could be observed with respect to standard errors. Conclusions Understanding the conceptual differences between mixed and marginal beta regression models is important for their proper use in the analysis of longitudinal HRQL data. Beta regression fits the typical distribution of HRQL data better than linear mixed models, however, if focus is on estimating group mean scores rather than making individual predictions, the two methods might not differ substantially.

  5. Health-related quality of life among older adults with arthritis

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    Gold Carol H

    2004-01-01

    Full Text Available Abstract Background Health-related quality of life (HRQOL is a key outcome in arthritis, but few population-based studies have examined the relationship of specific arthritic conditions, such as osteoarthritis (OA and rheumatoid arthritis (RA with HRQOL. Methods Older adults in Pennsylvania completed a mail version of the Centers for Disease Control and Prevention (CDC HRQOL modules. Medicare data were used to identify subjects with OA, RA, and no arthritis diagnosis. We compared HRQOL responses among these groups, and we also examined relationships of demographic characteristics to HRQOL among subjects with arthritis. Results In analyses controlling for demographic characteristics and comorbidity, subjects with OA and RA had poorer scores than those without arthritis on all HRQOL items, including general health, physical health, mental health, activity limitation, pain, sleep, and feeling healthy and full of energy. HRQOL scores were also lower for those with RA compared to OA. Among individuals with arthritis, all subject characteristics (including age, race, sex, nursing home residence, marital status, income, and comorbid illnesses were significantly related to at least one HRQOL item. Older age, nursing home residence, and greater comorbidity were the most consistently associated with poorer HRQOL. Conclusions Results of this study show that both OA and RA have a significant impact on multiple dimensions of HRQOL among older adults. Results also suggest the CDC HRQOL items are suitable for use among older adults and in mail surveys. Due to the rising number of older adults in many countries, the public health burden of arthritis is expected to increase dramatically. Efforts are needed to enhance access to medical care and disseminate self-management interventions for arthritis.

  6. Long-Term Trajectories of Health-Related Quality of Life in Individuals With Cerebral Palsy : A Multicenter Longitudinal Study

    NARCIS (Netherlands)

    Tan, Siok Swan; van Meeteren, Jetty; Ketelaar, Marjolijn; Schuengel, Carlo; Reinders - Messelink, Heelen; Raat, Hein; Dallmeijer, Annet J.; Roebroeck, Marij E.

    2014-01-01

    Objectives: To (1) determine the long-term trajectory of health-related quality of life (HRQOL) for the dimensions of physical complaints and motor, psychological, and social functioning for groups of individuals with cerebral palsy (CP) aged 1 to 24 years; (2) assess the variability in HRQOL within

  7. Health-related quality of life outcomes following elective open or endovascular AAA repair: a randomized controlled trial.

    NARCIS (Netherlands)

    Lottman, P.E.M.; Laheij, R.J.F.; Cuypers, P.W.; Bender, M.H.M.; Buth, J.

    2004-01-01

    PURPOSE: To assess health-related quality of life outcomes after endovascular versus open abdominal aortic aneurysm repair. METHODS: Participants were randomly assigned to receive either endovascular or open abdominal aortic aneurysm (AAA) surgery according to a rate of 3 endovascular patients to 1

  8. Participation as an outcome measure in psychosocial oncology : content of cancer-specific health-related quality of life instruments

    NARCIS (Netherlands)

    van der Mei, Sijrike F.; Dijkers, Marcel P. J. M.; Heerkens, Yvonne F.

    2011-01-01

    To examine to what extent the concept and the domains of participation as defined in the International Classification of Functioning, Disability and Health (ICF) are represented in general cancer-specific health-related quality of life (HRQOL) instruments. Using the ICF linking rules, two coders ind

  9. The Spirituality Index of Well-Being: A New Instrument for Health-Related Quality-of-Life Research

    OpenAIRE

    Daaleman, Timothy P.; Frey, Bruce B.

    2004-01-01

    PURPOSE Despite considerable interest in examining spirituality in health-related quality-of-life studies, there is a paucity of instruments that measure this construct. The objective of this study was to test a valid and reliable measure of spirituality that would be useful in patient populations.

  10. Self-reported health-related quality of life in kindergarten children : psychometric properties of the Kiddy-KINDL

    NARCIS (Netherlands)

    Villalonga-Olives, E.; Kiese-Himmel, C.; Witte, C.; Almansa, J.; Dusilova, I.; Hacker, K.; von Steinbuechel, N.

    2015-01-01

    Objectives: To assess the psychometric properties of the German self-reported version of the Kiddy-KINDL that measures Health Related Quality of Life (HRQoL) in 3 to 5 year old kindergarten children. Study design: The population of the study comprised baseline data of a longitudinal study whose main

  11. Evaluating the satisfaction of immigrant women from a rural community regarding family functioning and health-related quality of life.

    Science.gov (United States)

    Tsai, Su-Ying; Sun, Wen-Jung

    2013-01-01

    Transnational marriages in Taiwan are largely mediated by marriage brokers. The present study was conducted to evaluate the satisfaction of immigrant women with their family function and health-related quality of life in a rural township in southern Taiwan. Data were collected from January 1, 2006 to November 31, 2006, and 157 immigrants agreed to participate in the study, with a 79.3% response rate. A structured questionnaire was used for data collection. The interviewers also collected information on the immigrants' and husbands' demographics, self-reported mental conditions, family function using a Family APGAR questionnaire (Adaptability, Partnership, Growth, Affection, and Resolve), and health-related quality of life. Marriage arranged through a marriage broker and having emotional distress were factors that were strongly associated with lower Family APGAR scores. Based on multiple regression models, higher Family APGAR scores were more positively related to vitality and mental health scales. Self-reported mental conditions, including feeling economic distress, emotional distress, loneliness, and having sleep problems, were negatively associated with most scales of the health-related quality of life. Female migrants' mental health was significantly related to their health-related quality of life. These findings suggest that migrant women must be educated regarding the importance of mental health by physicians and hygiene authorities in Taiwan. PMID:23517512

  12. Correlation between changes in diastolic dysfunction and health-related quality of life after cardiac rehabilitation program in dilated cardiomyopathy

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    Sherin H.M. Mehani

    2013-03-01

    Full Text Available Chronic heart failure (CHF is a complex syndrome characterized by progressive decline in left ventricular function, low exercise tolerance and raised mortality and morbidity. Left ventricular diastolic dysfunction plays a major role in CHF and progression of most cardiac diseases. The current recommended goals can theoretically be accomplished via exercise and pharmacological therapy so the aim of the present study was to evaluate the impact of cardiac rehabilitation program on diastolic dysfunction and health related quality of life and to determine the correlation between changes in left ventricular diastolic dysfunction and domains of health-related quality of life (HRQoL. Forty patients with chronic heart failure were diagnosed as having dilated cardiomyopathy (DCM with systolic and diastolic dysfunction. The patients were equally and randomly divided into training and control groups. Only 30 of them completed the study duration. The training group participated in rehabilitation program in the form of circuit-interval aerobic training adjusted according to 55–80% of heart rate reserve for a period of 7 months. Circuit training improved both diastolic and systolic dysfunction in the training group. On the other hand, only a significant correlation was found between improvement in diastolic dysfunction and health related quality of life measured by Kansas City Cardiomyopathy Questionnaire. It was concluded that improvement in diastolic dysfunction as a result of rehabilitation program is one of the important underlying mechanisms responsible for improvement in health-related quality of life in DCM patients.

  13. Immunotherapy improves health-related quality of life of adult patients with dermal reactions following yellow jacket stings

    NARCIS (Netherlands)

    Oude Elberink, J. N. G.; van der Heide, S.; Guyatt, G. H.; Dubois, A. E. J.

    2009-01-01

    In many European centers insect venom allergic patients with a reaction confined to the skin are only offered an epinephrine auto-injector and not venom immunotherapy (VIT). Previously we showed that VIT improves health-related quality of life (HRQL) of yellow jacket allergic patients with more than

  14. Do Clinical and Demographic Features of Patients with Upper-Gastrointestinal Cancer Affect their Health-related Quality of Life?

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    Ramezan-Ali Esmaili-Hesari

    2012-01-01

    Conclusion: SCC is predominant type of upper GI cancer in Khorasan provinces similar to the high risk area in Northern Iran. The specific health-related quality of life tool (EORTC QLQ-OG25 was able to distinguish most of the symptoms in patients with upper GI cancer .

  15. Monitoring Health Related Quality of Life in paediatric practice: development of an innovative web-based application

    NARCIS (Netherlands)

    L. Haverman; V. Engelen; M.A.J. van Rossum; H.S.A. Heymans; M.A. Grootenhuis

    2011-01-01

    ABSTRACT: BACKGROUND: Health Related Quality of Life (HRQOL) questionnaires are increasingly used in clinical practice. These Patient Reported Outcomes (PROs) are provided to the paediatrician to facilitate communication with patients during a consultation. The aim of the current article is to descr

  16. Impact of personality and psychological distress on health-related quality of life in kidney transplant recipients

    NARCIS (Netherlands)

    Prihodova, Lucia; Nagyova, Iveta; Rosenberger, Jaroslav; Roland, Robert; van Dijk, Jitse P.; Groothoff, Johan W.

    2010-01-01

    P>Health-related quality of life (HRQoL) has become an important outcome in the evaluation of kidney transplantation (KT). Although the medical and sociodemographic predictors of HRQoL in patients after KT are well known, there is still a lack of knowledge about the psychological factors involved. T

  17. Exercise, Diet, and Stress Management as Mediators between Functional Disability and Health-Related Quality of Life in Multiple Sclerosis

    Science.gov (United States)

    Sung, Connie; Chiu, Chung-Yi; Lee, Eun-Jeong; Bezyak, Jill; Chan, Fong; Muller, Veronica

    2013-01-01

    The main objective of this study was to examine the mediational and moderational effect of exercise, diet, and stress management on the relationship between functional disability and health-related quality of life. Quantitative descriptive research design using multiple regression and correlation techniques was used. Participants were 215…

  18. Effect of psychological intervention on health-related quality of life in people with systemic lupus erythematosus: A systematic review

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    Hui Liang

    2014-09-01

    Conclusions: The results show that psychological interventions can effectively improve the health-related quality of life in patients with SLE. The full benefit and clinical performance of psychological care requires further investigation by a series of multicenter, large-sample size randomized controlled trails.

  19. Formoterol used as needed improves health-related quality of life in asthmatic patients uncontrolled with inhaled corticosteroids

    NARCIS (Netherlands)

    Stahl, E; Postma, DS; Svensson, K; Tattersfield, AE; Eivindson, A; Schreurs, A; Lofdahl, CG

    2003-01-01

    Clinical benefits have been shown to occur when using the long-acting beta(2)-agonist formoterol 4.5 mug for as-needed medication rather than terbutaline 500 mug in patients with unstable asthma taking an inhaled corticosteroid. This study compared their effects on health-related quality of Life and

  20. Hidden consequences of success in pediatrics: parental health-related quality of life—results from the Care Project

    NARCIS (Netherlands)

    J. Hatzmann; H.S.A. Heymans; A. Ferrer-i-Carbonell; B.M.S. van Praag; M.A. Grootenhuis

    2008-01-01

    CONTEXT. The number of parents who care for a chronically ill child is increasing. Because of advances in medical care, parental caring tasks are changing. A detailed description of parental health-related quality of life will add to the understanding of the impact of caring for a chronically ill ch

  1. A Viewpoint on Wearable Technology-Enabled Measurement of Wellbeing and Health-Related Quality of Life in Parkinson's Disease.

    Science.gov (United States)

    van Uem, Janet M T; Isaacs, Tom; Lewin, Alan; Bresolin, Eros; Salkovic, Dina; Espay, Alberto J; Matthews, Helen; Maetzler, Walter

    2016-03-10

    In this viewpoint, we discuss how several aspects of Parkinson's disease (PD) - known to be correlated with wellbeing and health-related quality of life-could be measured using wearable devices ('wearables'). Moreover, three people with PD (PwP) having exhaustive experience with using such devices write about their personal understanding of wellbeing and health-related quality of life, building a bridge between the true needs defined by PwP and the available methods of data collection. Rapidly evolving new technologies develop wearables that probe function and behaviour in domestic environments of people with chronic conditions such as PD and have the potential to serve their needs. Gathered data can serve to inform patient-driven management changes, enabling greater control by PwP and enhancing likelihood of improvements in wellbeing and health-related quality of life. Data can also be used to quantify wellbeing and health-related quality of life. Additionally these techniques can uncover novel more sensitive and more ecologically valid disease-related endpoints. Active involvement of PwP in data collection and interpretation stands to provide personally and clinically meaningful endpoints and milestones to inform advances in research and relevance of translational efforts in PD. PMID:27003779

  2. Co-morbidities are the key nominators of the health related quality of life in mild and moderate COPD

    NARCIS (Netherlands)

    Koskela, Jukka; Kilpeläinen, Maritta; Kupiainen, Henna; Mazur, Witold; Sintonen, Harri; Boezen, Marike; Lindqvist, Ari; Postma, Dirkje; Laitinen, Tarja; Boezen, Hendrika

    2014-01-01

    BACKGROUND: Co-morbidities are common in chronic obstructive pulmonary disease (COPD). We assessed the contribution of common co-morbidities on health related quality of life (HRQoL) among COPD patients. METHODS: Using both generic (15D) and respiratory-specific (AQ20) instruments, HRQoL was assesse

  3. The Effects of Strength Training on Strength and Health-Related Quality of Life in Older Adult Women.

    Science.gov (United States)

    Damush, Teresa M.; Damush, Joseph G., Jr.

    1999-01-01

    Evaluates the short-term effects of an accessible exercise intervention on the strength and health-related quality of life among older women. Results of an 8-week resistance training intervention revealed significant increases in three major muscles. However, there were no significant changes on either mental or physical health functioning.…

  4. Measuring health-related quality of life in adults with chronic conditions in primary care settings

    Science.gov (United States)

    Hand, Carri

    2016-01-01

    Abstract Objective To describe health-related quality of life (HRQOL) conceptual frameworks, critically review 3 commonly used HRQOL scales relevant to adults with chronic conditions in primary care settings, and make recommendations for using HRQOL scales in primary care practice. Data sources Information was accessed regarding HRQOL conceptual and theoretical approaches. A comprehensive search strategy identified 3 commonly used scales that met the review criteria and evidence regarding use of the scales in adults with chronic conditions in community settings. Scale selection Scales were selected if they were designed for clinical use; were easy to administer; were generic and broad in content areas; and contained some individualized items. Scales were critiqued according to content development, theoretical basis, psychometric properties, scoring, feasibility, the concepts being measured, and the number of items that measured an individualized concept. Synthesis Early HRQOL approaches focused on health and functional status while recent approaches incorporate individualized concepts such as the person’s own values and the environment. The abbreviated World Health Organization Quality of Life Scale (WHOQOL-BREF), the 36-Item Short Form Health Survey (SF-36), and the Duke Health Profile were critiqued. All address physical, mental, and social domains, while the WHOQOL-BREF also addresses environment. Psychometric evidence supports use of the SF-36 and WHOQOL-BREF with this population. The SF-36 has the most evidence of responsiveness but has some floor and ceiling effects, while the WHOQOL-BREF does not appear to have floor or ceiling effects but has limited evidence of responsiveness. The WHOQOL-BREF has the highest proportion of individualized items. Conclusion Measurement of HRQOL in adults with chronic conditions can support patient management and contribute to primary care service evaluation. Scales that are based on a broad definition of health and that

  5. Improvement in health-related quality of life in osteoporosis patients treated with teriparatide

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    Papaioannou Alexandra

    2008-11-01

    Full Text Available Abstract Background Individuals with osteoporosis and recent vertebral fractures suffer from pain and impaired health-related quality of life (HRQL. To determine whether patients with osteoporosis treated with teriparatide experienced improvement in HRQL and pain symptoms after several months of therapy. Methods We retrospectively studied a sample of osteoporosis patients treated with teriparatide in a Canadian rheumatology practice. We included patients that received teriparatide therapy with baseline and follow-up Mini-Osteoporosis Quality of Life Questionnaire (OQLQ data. Follow-up data was measured at three or six months. We used a paired Student's t-test to compare baseline and follow-up measurements for each of the questionnaire's ten questions (five domains. Statistical analysis was also repeated to only include patients who suffered a prior vertebral fracture. Results 57 patients were included in the study, including 47 women. The mean age was 63.8 years (standard deviation 12.1 years. About sixty five percent (37/57 had previously sustained one or more osteoporotic fractures and about 38.6% (22/57 had suffered a prior vertebral fracture. About 44% (25/57 of individuals were taking one or more types of pain medications regularly prior to starting therapy. At follow-up, significant improvements were observed in the OQLQ domains of pain symptoms. This was seen when all patients on teriparatide were included, and also when only patients with prior vertebral fractures were included. There was also an improvement in emotional functioning, relating to fear of falling at 3 months follow-up (p = 0.019. Respondents also reported improvement in the domain of activities of daily living, relating to vacuuming at 6 months follow-up (p = 0.036, and an improvement in the leisure domain, relating to ease of traveling in the prior vertebral fracture population at 3 months follow-up (p = 0.012. However, there was no significant improvement observed in the

  6. Health related quality of life among Iraqi immigrants settled in Malaysia

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    Daher Thaaer M

    2011-05-01

    Full Text Available Abstract Background Migrants everywhere face several demands for health and maintaining good health and quality of life could be challenging. Iraqis are the second largest refugee group that has sought refuge in the recent years, yet little is known about their health related quality of life (HRQOL. The study aims at assessing the HRQOL among Iraqis living in Malaysia. Methods A self-administered Arabic version of Sf-36 questionnaire was distributed among 300 Iraqi migrants in Malaysia. The questionnaire taps eight concepts of physical and mental health to assess the HRQOL. Univariate analysis was performed for group analysis (t test, ANOVA and Multiple Linear Regression was used to control for confounding effects. Results Two hundred and fifty three participants ranging in age from 18 to 67 years (Mean = 33.6 returned the completed questionnaire. The majority was males (60.1% and more than half of the respondents (59.5% were married. Less than half (45.4% and about a quarter (25.9% reported bachelor degree and secondary school education respectively and the remaining 28.7% had either a master or a PhD degree. Univariate analysis showed that the HRQOL scores among male immigrants were found to be higher than those of females in physical function (80.0 vs. 73.5, general health (72.5 vs. 60.7 and bodily pain (87.9 vs. 72.5 subscales. The youngest age group had significantly higher physical function (79.32 and lower mental health scores (57.62. The mean score of physical component summary was higher than the mental component summary mean score (70.22 vs. 63.34. Stepwise multiple linear regression, revealed that gender was significantly associated with physical component summary (β = - 6.06, p = 0.007 and marital status was associated with mental component summary (β = 7.08, p = 0.003. Conclusions From the data it appears that Iraqi immigrants living in Malaysia have HRQOL scores that might be considered to indicate a relatively moderate HRQOL

  7. Health-related quality of life, and its determinants, among older people in rural Vietnam

    Directory of Open Access Journals (Sweden)

    Hoi Le V

    2010-09-01

    Full Text Available Abstract Background The proportion of people in Vietnam aged 60 and above has increased rapidly in recent decades. However, there is a lack of evidence, particularly in rural settings, on their health-related quality of life (HRQoL within the context of socioeconomic changes and health-sector reform in the country. This study assesses the level and determinants of HRQoL in a rural district in order to provide evidence for designing and implementing appropriate health policies. Methods In 2007, 2,873 people aged 60+ living in 2,240 households randomly selected from the FilaBavi demographic surveillance site (DSS were interviewed using a generic EQ-5D questionnaire to assess their HRQoL. Socioeconomic characteristics of the people and their households were extracted from the DSS's re-census that year, and the EQ-5D index was calculated based on the time trade-off tariff. Multilevel-multivariate linear regression analysis was performed to measure the affect of socioeconomic factors on HRQoL. Results The EQ-5D index at old age was found to be 0.876 (95%CI: 0.870-0.882. Age between 60-69 or 70-79 years, position as household head, working until old age, literacy, and belonging to better wealth quintiles are determinants of higher HRQoL. Ageing has a primary influence on the deterioration of HRQoL at older ages, mainly due to reduction in physical rather than mental functions. Educational disparity in HRQoL is low, and exists mostly between basic and higher levels of education. Being a household head and working at old age are advantageous for attaining better quality of life in physical rather than psychological terms. Economic conditions affect HRQoL through sensory rather than physical utilities. Long-term living conditions more likely affect HRQoL than short-term economic conditions. Conclusions HRQoL at old age is at a high level, and varies substantially according to socioeconomic factors. Its determinants should be addressed in social and

  8. Health-related Quality of Life Scores Changes Significantly within the First Three Months After Hernia Mesh Repair

    DEFF Research Database (Denmark)

    Christoffersen, Mette W; Rosenberg, Jacob; Jorgensen, Lars Nannestad; Bytzer, Peter; Bisgaard, Thue

    2014-01-01

    BACKGROUND: Patient-related outcome measures (PROM) such as quality of life (QoL) after hernia repair are important to monitor, since QoL is an important indication of a hernia repair. Carolinas Comfort Scale (CCS) is a hernia-specific questionnaire regarding health-related QoL after a mesh hernia...... changed significantly with time during the 90-day study period. Furthermore, CCS and VAS showed significant agreement and correlation (ρ = 0.52-0.82, P < 0.001). CONCLUSIONS: The present study is the first to demonstrate significant changes over time in health-related QoL using the CCS after four...

  9. Psychometric properties of the German version of the MacNew heart disease health-related quality of life questionnaire

    Directory of Open Access Journals (Sweden)

    Gramm Lukas

    2012-07-01

    Full Text Available Abstract Background There is a lack of German-language, disease-specific health related quality of life instruments applicable in cardiac rehabilitation. The purpose of this project was to investigate the psychometric properties of the German version of the MacNew Heart Disease Health-related Quality of Life Questionnaire (MacNew in patients undergoing cardiac rehabilitation. Methods The MacNew was filled out by 5692 inpatients. We analysed acceptance (number of missing values, ceiling and floor effects, reliability (Cronbach’s α, factor structure (confirmatory factor analysis, construct validity (correlation with a generic health-related quality of life instrument, and sensitivity to change. Results Two items had more than 7% missing data. We observed neither floor nor ceiling effects. Cronbach’s α of the scales ranged from 0.78 (physical scale to 0.95 (global scale. Confirmatory factor analysis failed to reproduce the proposed factor structure (CFI = 0.882; TLI = 0.871; RMSEA = 0.074. We therefore drafted our own model (CFI = 0.932; TLI = 0.921; RMSEA = 0.064, and observed a correlation pattern largely conforming to the hypotheses with a generic health-related quality of life instrument. The effect sizes we noted between the start and end of rehabilitation fell between 0.66 and 0.74; at the 6-month follow-up they ranged from 0.69 to 0.92. Conclusions The German version of the MacNew Heart Disease Health-related Quality of Life Questionnaire is a suitable instrument with which to measure the impairment experienced by individuals with heart disease during inpatient cardiologic rehabilitation. The social and the global scale must be interpreted cautiously.

  10. A long life in good health: subjective expectations regarding length and future health-related quality of life

    OpenAIRE

    Rappange, David; Brouwer, Werner; van Exel, Job

    2016-01-01

    textabstractBackground: Subjective life expectancy is considered relevant in predicting mortality and future demand for health services as well as for explaining peoples’ decisions in several life domains, such as the perceived impact of health behaviour changes on future health outcomes. Such expectations and in particular subjective expectations regarding future health-related quality of life remain understudied. The purpose of this study was to investigate individuals’ subjective quality a...

  11. Sleep, stress, neurocognitive profile and health-related quality of life in adolescents with idiopathic musculoskeletal pain

    OpenAIRE

    Juliana Molina; Flávia Heloísa Dos Santos; Maria Teresa R.A. Terreri; Melissa Mariti Fraga; Simone Guerra Silva; Maria Odete E. Hilário; Len, Claudio A

    2012-01-01

    OBJECTIVES: The aims of this study were to measure levels of sleep, stress, and depression, as well as health-related quality of life, and to assess the neurocognitive profiles in a sample of adolescents with idiopathic musculoskeletal pain. METHODS: Nineteen adolescents with idiopathic musculoskeletal pain and 20 age-matched healthy control subjects were evaluated regarding their levels of sleep and stress, as well as quality of life, and underwent neurocognitive testing. RESULTS: The sample...

  12. Influence of Social Support on Health-Related Quality of Life in New-Generation Migrant Workers in Eastern China

    OpenAIRE

    Haiyan Xing; Wei Yu; Sanmei Chen; Dengke Zhang; Rongmei Tan

    2013-01-01

    Background: The World Health Organization Quality of Life-BREF (WHOQOL-BREF) has generally been used for patients, few studies in migrants who move from rural to urban within one country. Many studies asserted that social isolation presents a risk to individual health. Poor social networks are associated with worse QOL. This study examined health-related quality of life (HRQOL) and social support in new-generation migrant workers and compared it with urban workers. Methods: Nine hundred thirt...

  13. Health Related Quality of Life in Patients with Coronary Heart Disease: Psychological and Socio-Demographical Determinants

    OpenAIRE

    Isaac Rahimian-Boogar; Reza Rostami

    2014-01-01

    Background: Coronary heart disease is the universal principal cause for decreased quality of life, morbidity, and mortality in adulthood. This study seeks to indicate the psychological and socio-demographical determinants of the health related quality of life in patients with coronary heart disease in Iran. Materials and Methods: In this cross-sectional descriptive design, 205 patients with coronary heart disease among the patients diagnosed with coronary heart disease in Shahid Rajayee he...

  14. Health-Related Quality of Life in Assyrian/Syrian and Swedish-Born Patients with Type 2 Diabetes

    OpenAIRE

    Taloyan, Marina; Saleh-Stattin, Nuha; Johansson, Sven-Erik; Agréus, Lars; Wändell, Per

    2013-01-01

    Aims: To investigate whether there is an association between ethnicity and healthrelated quality of life in patients with type 2 diabetes and to analyze if the association remains after adjusting for possible confounders. Methodology: A 12-item Short-form Health Survey - SF-12 was used. The associations between health-related quality of life and ethnicity, sex, age, marital status, educational status, BMI and age of onset of diabetes, were evaluated using linear regression analyses (β-co...

  15. Evaluation of Health Related Quality of Life in Patient with Oral Cavity Squamous Cell Carcinoma Receiving Chemotherapy

    OpenAIRE

    Mistry CB; Rana DS; Batra V

    2015-01-01

    Objective: To evaluate impact of chemotherapy on Health Related Quality of Life (HRQOL) in patients of oral cavity squamous cell carcinoma (OCSCC) by analysis of two different treatments named Concurrent Chemo - Radiation (CTRT) and Neo-Adjuvant Chemotherapy (NACT). Study Design and Instrument: Prospective longitudinal study by evaluation HRQOL by general quality of life (QLQC30) and head & neck specific (QLQ-H&N35) questionnaires of the European Organization for Res...

  16. Impact of socioeconomic status and subjective social class on overall and health-related quality of life

    OpenAIRE

    Kim, Jae-Hyun; Park, Eun-Cheol

    2015-01-01

    Background Our objective was to investigate the impact of socioeconomic status and subjective social class on health-related quality of life (HRQOL) vs. overall quality of life (QOL). Methods We performed a longitudinal analysis using data regarding 8250 individuals drawn from the Korean Longitudinal Study of Aging (KLoSA). We analyzed differences between HRQOL and QOL in individuals of various socioeconomic strata (high, middle, or low household income and education levels) and subjective so...

  17. Health-related and overall quality of life of patients with chronic hip and knee complaints in general practice

    OpenAIRE

    Waal, de, M.; Terwee, C. B.; Windt - Mens, van der, D.A.W.M.; Bouter, L M; Dekker, J

    2005-01-01

    BACKGROUND: Information about quality of life of patients with chronic hip or knee complaints in general practice is scarce. This study describes the health-related and overall quality of life (HRQL) of these complaints. METHODS: Data were obtained from a cohort study in general practice. HRQL at three months follow-up was analysed. HRQL was measured as: symptoms, physical, psychological and social functioning, and general health perceptions, using the Western Ontario and McMaster Universitie...

  18. Health related quality of life measured by SF-36: a population-based study in Shanghai, China

    OpenAIRE

    Liu Wenbin; Wu Meijing; Ma Xiuqiang; Yan Xiaoyan; Zhao Yanfang; Wu Cheng; Wang Rui; Gu Zheng; Zhao June; He Jia

    2008-01-01

    Abstract Background Health related quality of life (HRQL) is a research topic that has attracted increasing interests around the world over the past two decades. The 36-item Short Form (SF-36) is a commonly used instrument for measuring HRQL. However, the information on Chinese adults' quality of life is limited. This paper reports on the feasibility of using the Mandarin version of SF-36 to evaluate HRQL in the population of Shanghai, China. Methods A total of 1034 subjects were randomly sam...

  19. Self-efficacy and health-related quality of life in family carers of people with dementia

    DEFF Research Database (Denmark)

    Crellin, Nadia E.; Orrell, Martin; McDermott, Orii;

    2014-01-01

    -being. Findings do not support the independence of the negative and positive pathways. The review was valuable in highlighting methodological challenges confronting this area of research, particularly the conceptualisation and measurement issues surrounding both SE and health-related QoL. Conclusions: The model......Objectives: This review aims to explore the role of self-efficacy (SE) in the health-related quality of life (QoL) of family carers of people with dementia. Methods: A systematic review of literature identified a range of qualitative and quantitative studies. Search terms related to caring, SE, and...... dementia. Narrative synthesis was adopted to synthesise the findings. Results: Twenty-two studies met the full inclusion criteria, these included 17 quantitative, four qualitative, and one mixed-method study. A model describing the role of task/domain-specific SE beliefs in family carer health-related Qo...

  20. Self-perceived health-related quality of life of Indian children with specific learning disability

    Directory of Open Access Journals (Sweden)

    S Karande

    2012-01-01

    Full Text Available Background: Specific learning disability (SpLD often remains undetected, resulting in the afflicted child experiencing chronic poor school performance. Aims: To measure and analyze the self-perceived health-related quality of life (HRQoL of children with newly-diagnosed SpLD. Settings and Design: Cross-sectional questionnaire-based study in our clinic. Materials and Methods: From February to December 2008, 150 children consecutively diagnosed as having SpLD were enrolled and their HRQoL documented using the DISABKIDS chronic generic module self-report version instrument. Statistical Analysis: Multiple regression analysis was carried out for determining the ′independent′ impact that each of the clinical and socio-demographic variables had on a poor facet score outcome and on a poor total score outcome. Results: Clinically significant deficits were detected in all 6 facets, namely: ′large deficits (effect size ≥−0.8′ in "social exclusion", "emotion", "limitation", "treatment", and "independence"; and ′medium deficit (effect size −0.5 to <−0.8′ in "social inclusion"; and ′large deficit′ in "total score". Multivariate analysis revealed that: (i not belonging to the upper socio-economic strata of society was an independent predictor of a poor "independence" facet outcome (P=0.010, OR=1.99, 95% CI: 1.18 to 3.37; (ii not having experienced class detainment was an independent predictor of a poor "emotion" facet outcome (P=0.008, OR=3.04, 95% CI: 1.34 to 6.85; (iii first-born status was an independent predictor of a poor "limitation" facet outcome (P=0.022, OR=2.60, 95% CI: 1.15 to 5.90; and (iv female gender was an independent predictor of a poor "social exclusion" facet outcome (P=0.024, OR=0.28, 95% CI: 0.09 to 0.85 and a poor "overall health" outcome (P=0.025, OR=0.32, 95% CI: 0.12 to 0.87. Conclusions: Children with newly-diagnosed SpLD perceive their psychosocial, physical, and overall HRQoL to be significantly compromised.

  1. Health related quality of life trajectories and predictors following coronary artery bypass surgery

    Directory of Open Access Journals (Sweden)

    Worcester Marian UC

    2006-08-01

    Full Text Available Abstract Background Many studies have demonstrated that health related quality of life (HRQoL improves, on average, after coronary artery bypass graft surgery (CABGS. However, this average improvement may not be realized for all patients, and it is possible that there are two or more distinctive groups with different, possibly non-linear, trajectories of change over time. Furthermore, little is known about the predictors that are associated with these possible HRQoL trajectories after CABGS. Methods 182 patients listed for elective CABGS at The Royal Melbourne Hospital completed a postal battery of questionnaires which included the Short-Form-36 (SF-36, Profile of Mood States (POMS and the Everyday Functioning Questionnaire (EFQ. These data were collected on average a month before surgery, and at two months and six months after surgery. Socio-demographic and medical characteristics prior to surgery, as well as surgical and post-surgical complications and symptoms were also assessed. Growth curve and growth mixture modelling were used to identify trajectories of HRQoL. Results For both the physical component summary scale (PCS and the mental component summary scale (MCS of the SF-36, two groups of patients with distinct trajectories of HRQoL following surgery could be identified (improvers and non-improvers. A series of logistic regression analyses identified different predictors of group membership for PCS and MCS trajectories. For the PCS the most significant predictors of non-improver membership were lower scores on POMS vigor-activity and higher New York Heart Association dyspnoea class; for the MCS the most significant predictors of non-improver membership were higher scores on POMS depression-dejection and manual occupation. Conclusion It is incorrect to assume that HRQoL will improve in a linear fashion for all patients following CABGS. Nor was there support for a single response trajectory. It is important to identify characteristics of

  2. Health related quality of life after extremely preterm birth: a matched controlled cohort study

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    Eide Geir E

    2010-05-01

    Full Text Available Abstract Background The majority of infants born before the last trimester now grow up. However, knowledge on subsequent health related quality of life (HRQoL is scarce. We therefore aimed to compare HRQoL in children born extremely preterm with control children born at term. Furthermore, we assessed HRQoL in relation to perinatal and neonatal morbidity and to current clinical and sociodemographic characteristics. Method The Child Health Questionnaire (CHQ-PF50 and a general questionnaire were applied in a population based cohort of 10 year old children born at gestational age ≤ 28 weeks or with birth weight ≤ 1000 grams in Western Norway in 1991-92 and in term-born controls, individually matched for gender and time of birth. The McNemar test and paired t-tests were used to explore group differences between preterms and matched controls. Paired regression models and analyses of interaction (SPSS mixed linear model were used to explore potential effects of sociodemographic and clinical characteristics on HRQoL in the two groups. Results All 35 eligible preterm children participated. None had major impairments. Learning and/or attention problems were present in 71% of preterms and 20% of controls (odds ratio (OR: 7.0; 95% confidence interval (CI: 2.2 to 27.6. Insufficient professional support was described by 36% of preterm vs. 3% of control parents (OR: infinite; CI: 2.7 to infinite. Preterms scored lower on eight CHQ-PF50 sub-scales and the two summary scores, boys accounting for most of the deficits in areas of behavior, psychosocial functioning and parental burden. HRQoL was associated with learning and/or attention problems in both preterm and control children, significantly more so in preterms in areas related to health and parental burden. Within the preterm group, HRQoL was mostly unrelated to perinatal and neonatal morbidity. Conclusions HRQoL for children born extremely preterm, and particularly for boys, was described by parents to

  3. Health-related quality of life of child and adolescent retinoblastoma survivors in the Netherlands

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    Bezemer Pieter D

    2007-12-01

    Full Text Available Abstract Background To assess health-related quality of life (HRQoL in children (8–11 years and adolescents (12–18 years who survived retinoblastoma (RB, by means of the KIDSCREEN self-report questionnaire and the proxy-report version. Methods This population-based cross-sectional study (participation rate 70% involved 65 RB survivors (8–18 years and their parents. Child/adolescents' and parents' perception of their youth's HRQoL was assessed using the KIDSCREEN, and the results were compared with Dutch reference data. Relations with gender, age, marital status of the parents, and visual acuity were analyzed. Results RB survivors reported better HRQoL than did the Dutch reference group on the dimensions "moods and emotions" and "autonomy". Increased ratings of HRQoL in RB survivors were mainly seen in perceptions of the younger children and adolescent girls. RB survivors with normal visual acuity scored higher on "physical well-being" than visually impaired survivors. Age was negatively associated with the dimensions "psychological well-being", "self-perception" (according to the child and parent reports and "parent relations and home life" (according to the child. "Self-perception" was also negatively associated with visual acuity (according to the child. Only parents of young boys surviving RB reported lower on "autonomy" than the reference group, and parents of low visual acuity and blind RB survivors reported higher on "autonomy" than parents of visually unimpaired survivors. Survivors' perceptions and parents' perceptions correlated poorly on all HRQoL dimensions. Conclusion RB survivors reported a very good HRQoL compared with the Dutch reference group. The perceptions related to HRQoL differ substantially between parents and their children, i.e. parents judge the HRQoL of their child to be relatively poorer. Although the results are reassuring, additional factors of HRQoL that may have more specific relevance, such as psychological

  4. Health-related quality of life in elderly patients hospitalized with chronic heart failure

    Directory of Open Access Journals (Sweden)

    Erceg P

    2013-11-01

    Full Text Available Predrag Erceg,1,2 Nebojsa Despotovic,1,2 Dragoslav P Milosevic,1,2 Ivan Soldatovic,3 Sanja Zdravkovic,2 Snezana Tomic,2 Ivana Markovic,2 Gordana Mihajlovic,2 Milan D Brajovic,4,5 Ognjen Bojovic,6 Bojana Potic,2 Mladen Davidovic1 1Department of Gerontology, Faculty of Medicine, University of Belgrade, 2Clinical Department of Geriatrics, Zvezdara University Hospital, 3Institute of Medical Statistics and Informatics, Faculty of Medicine, 4Department of Internal Medicine, Faculty of Dentistry, University of Belgrade, 5Clinical Department of Cardiology, Zvezdara University Hospital, Belgrade, Serbia; 6Department of Biomedicine, University of Bergen, Bergen, Norway Background: Chronic heart failure is a very common condition in the elderly, characterized not only by high mortality rates, but also by a strong impact on health-related quality of life (HRQOL. Previous studies of HRQOL in elderly heart failure subjects have included mostly outpatients, and little is known about determinants of HRQOL in hospitalized elderly population, especially in Serbia. In this study, we tried to identify factors that influence HRQOL in elderly patients hospitalized with chronic heart failure in Serbia. Methods: The study population consisted of 136 patients aged 65 years or older hospitalized for chronic heart failure. HRQOL was assessed using the Minnesota Living with Heart Failure questionnaire. Predictors of HRQOL were identified by multiple linear regression analysis. Results: Univariate analysis showed that patients with lower income, a longer history of chronic heart failure, and longer length of hospital stay, as well as those receiving aldosterone antagonists and digoxin, taking multiple medications, in a higher NYHA class, and showing signs of depression and cognitive impairment had significantly worse HRQOL. Presence of depressive symptoms (P<0.001, higher NYHA class (P=0.021, lower income (P=0.029, and longer duration of heart failure (P=0.049 were

  5. Oral health-related quality of life in an aging Canadian population

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    Kotzer Robert D

    2012-05-01

    Full Text Available Abstract Background The purpose of the study is to describe the impact of oral health-related quality of life (OHRQoL on the lives of pre-seniors and seniors living in Nova Scotia, Canada. Methods This cross-sectional study involved 1461 participants, grouped by age (pre-seniors [45–64] and seniors [65+] and residential status (long-term care facility [LTC] or community. OHRQoL was measured using the 14-item Oral Health Impact Profile questionnaire (OHIP-14 in a random digit dialing telephone survey (for community residents or a face-to-face interview (for LTC residents. Intra-oral examinations were performed by one of six dentists calibrated to W.H.O. standards. Results Approximately one in four pre-seniors and seniors reported at least one OHRQoL impact ‘fairly/very often’. The most commonly reported impacts were within the dimensions ‘physical pain’ and ‘psychological discomfort’. It was found that 12.2% of LTC residents found it uncomfortable to eat any foods ‘fairly/very’ often compared to 7.7% in the community, and 11.6% of LTC residents reported being self-conscious ‘fairly/very often’ compared to 8.2% in the community. Of those residing in the community, pre-seniors (28.8% reported significantly more impacts than seniors (22.0%; but there were no significant differences in OHRQoL between pre-seniors (21.2% and seniors (25.3% in LTC. Pre-seniors living in the community scored significantly higher than community dwelling seniors on prevalence, extent and severity of OHIP-14 scores. Logistic regression revealed that for the community dwelling sample, individuals living in rural areas in addition to those being born outside of Canada were approximately 2.0 times more likely to report an impact ‘fairly/very often’, whereas among the LTC sample, those having a high school education or less were 2.3 times more likely to report an impact. Conclusions Findings indicate that the oral health and OHRQoL of both pre

  6. The health related quality of life of Greek patients with chronic obstructive pulmonary disease

    Directory of Open Access Journals (Sweden)

    Alexandra Kopitopoulou

    2013-06-01

    Full Text Available SUMMARY.Background: Chronic Obstructive Pulmonary Disease (COPD is an advancing disease, characterized by progressive deterioration of lung function. The impact of the disease on human health is massive and it affects the health related quality of life (HRQoL of patients in every aspect. This study assessed HRQoL of Greek patients with COPD and its association with demographic and clinical factors, and compared the findings with with those of COPD studies in other countries. In addition, the cost of pharmaceutical treatment of these patients was assessed. Material and methods: The study group consisted of 136 Greek patients with COPD (103 men, mean age 64.7±9.2 years, mean FEV1 59±25.6% predicted.I Information was recorded about their demographic and clinical parameters. Their HRQoL was assessed using the Greek versions of the Medical Outcomes Study Short Form 12 (SF-12 and St George’s Respiratory Questionnaire (SGRQ. Results: The HRQoL of Greek patients with COPD was found to be significantly lower than both that in the general population and that of patients COPD reported in other countries. Almost all the HRQoL scores were shown to be associated with gender, educational and financial status, duration of symptoms, age at onset of symptoms, pack-years of cigarettes smoked, disease stage, degree of dyspnoea, pO2 and pCO2 levels, numbers of medical visits and hospital admissions, participation in rehabilitation programmes, and co-morbidities, such as cardiovascular disease and diabetes mellitus (DM. The average cost of pharmaceutical treatment was assessed at 110 ± 63 € / month and was associated with the stage of the disease, the smoking habit, the degree of dyspnoea, annual numbers of medical visits and admissions and nebulizer usage. Conclusions: The HRQoL of Greek patients with COPD is influenced by multiple parameters, which should all be taken into consideration when their treatment is being planned. Cost-effective studies should be

  7. Evaluating oral health-related quality of life measure for children and preadolescents with temporomandibular disorder

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    Castelo Paula M

    2011-05-01

    Full Text Available Abstract Background Oral health-related quality of life (OHRQoL in children and adolescents with signs and symptoms of temporomandibular disorder (TMD has not yet been measured. This study aimed to evaluate the validity and reliability of OHRQoL measure for use in children and preadolescents with signs and symptoms of TMD. Methods Five hundred and forty-seven students aged 8-14 years were recruited from public schools in Piracicaba, Brazil. Self-perceptions of QoL were measured using the Brazilian Portuguese versions of Child Perceptions Questionnaires (CPQ8-10 (n = 247 and CPQ11-14 (n = 300. A single examiner, trained and calibrated for diagnosis according to the Axis I of the Research Diagnostic Criteria for TMD (RDC/TMD, examined the participants. A self-report questionnaire assessed subjective symptoms of TMD. Intraexaminer reliability was assessed for the RDC/TMD clinical examinations using Cohen's Kappa (κ and intraclass correlation coefficient (ICC. Criterion validity was calculated using the Spearman's correlation, construct validity using the Spearman's correlation and the Mann-Whitney test, and the magnitude of the difference between groups using effect size (ES. Reliability was determined using Cronbach's alpha, alpha if the item was deleted and corrected item-total correlation. Results Intraexaminer reliability values ranged from regular (κ = 0.30 to excellent (κ = 0.96 for the categorical variables and from moderate (ICC = 0.49 to substantial (ICC = 0.74 for the continuous variables. Criterion validity was supported by significant associations between both CPQ scores and pain-related questions for the TMD groups. Mean CPQ8-10 scores were slightly higher for TMD children than control children (ES = 0.43. Preadolescents with TMD had moderately higher scores than the control ones (ES = 0.62; p 8-10 and 0.94 for CPQ11-14. For the overall CPQ8-10 and CPQ11-14 scales, the corrected item-total correlation coefficients ranged from 0

  8. Fee-for-service cancer rehabilitation programs improve health-related quality of life

    Science.gov (United States)

    Kirkham, A.A.; Neil-Sztramko, S.E.; Morgan, J.; Hodson, S.; Weller, S.; McRae, T.; Campbell, K.L.

    2016-01-01

    Background Rigorously applied exercise interventions undertaken in a research setting result in improved health-related quality of life (hrqol) in cancer survivors, but research to demonstrate effective translation of that research to practice is needed. The objective of the present study was to determine the effect of fee-for-service cancer rehabilitation programs in the community on hrqol and on self-reported physical activity and its correlates. Methods After enrolment and 17 ± 4 weeks later, new clients (n = 48) to two fee-for-service cancer rehabilitation programs completed the 36-Item Short Form Health Survey (rand-36: rand Corporation, Santa Monica, CA, U.S.A.), the Godin Leisure-Time Exercise Questionnaire, and questions about physical activity correlates. Normal fee-for-service operations were maintained, including a fitness assessment and individualized exercise programs supervised in a group or one-on-one setting, with no minimum attendance required. Fees were associated with the assessment and with each exercise session. Results Of the 48 participants, 36 (75%) completed both questionnaires. Improvements in the physical functioning, role physical, pain, and energy/fatigue scales on the rand-36 exceeded minimally important differences and were of a magnitude similar to improvements reported in structured, rigorously applied, and free research interventions. Self-reported levels of vigorous-intensity (p = 0.021), but not moderate-intensity (p = 0.831) physical activity increased. The number of perceived barriers to exercise (p = 0.035) and the prevalence of fatigue as a barrier (p = 0.003) decreased. Exercise self-efficacy improved only in participants who attended 11 or more sessions (p = 0.002). Exercise enjoyment did not change (p = 0.629). Conclusions Enrolment in fee-for-service cancer rehabilitation programs results in meaningful improvements in hrqol comparable to those reported by research interventions, among other benefits. The fee

  9. Health Related Quality of Life May Increase when Patients with a Stoma Attend Patient Education – A Case-Control Study

    OpenAIRE

    Anne Kjaergaard Danielsen; Jacob Rosenberg

    2014-01-01

    INTRODUCTION: Adaptation to living with a stoma is complex, and studies have shown that stoma creation has a great impact on patients' health related quality of life. The objective was to explore the effect of a structured patient education program on health related quality of life. Therefore, we implemented interventions aimed at increasing health related quality of life during and after hospital admission. MATERIALS AND METHODS: We designed a case/control study aimed at adult patients admit...

  10. The Intermediary Role of Self-Efficacy in Relation with Stress, Glycosylated Haemoglobin and Health-Related Quality of Life in Patients with Type2 Diabetes

    Directory of Open Access Journals (Sweden)

    A Alipour

    2012-12-01

    Full Text Available Background: Stress is not always a direct result of stressful conditions, but rather the way they are perceived. Thus individual variables that may be associated with perceived stress should be examined in stress studies. This study investigates the intermediary role of self-efficacy in relation with stress, glycosylated haemoglobin and health-related quality of life in patients with type2 diabetes.Methods: All women with diabetes in Yazd Diabetes Research Centre, in 2012, were considered and 80 women were selected by random sampling. They completed Shirer’s self-efficacy scale questionnaire, depression, anxiety and stress scale (DASS, and ADDQ0L19 questionnaire. Then they were introduced to the lab for blood test. Data were analysed by SPSS software and stepwise regression method.Results: Pearson correlation test results showed that the hemoglobin A1c (r = 0.35 and Quality of Life (r = -0.22 are associated with stress (P <0.05. As so hemoglobin A1c (r = 0.83 and Quality of Life (r = 0.37 with variable of self efficacy are associated positively and significantly (P <0.05. Results of stepwise regression also showed that self efficacy and stress scales 0.697 of variance hemoglobin A1c and 0.140 of variance of Quality of life explaining to do.Conclusion: The impact of stress on blood sugar and patients’ health-related quality of life can be influenced by their self-efficacy; therefore it is suggested that an educational intervention is done to increase patients’ self-efficacy to better cope with stress in their life.

  11. Analysis of Postsurgical Health-Related Quality of Life and Quality of Voice of Patients With Laryngeal Carcinoma

    Science.gov (United States)

    Luo, Jie; Wu, Jieli; Lv, Kexing; Li, Kaichun; Wu, Jianhui; Wen, Yihui; Li, Xiaoling; Tang, Haocheng; Jiang, Aiyun; Wang, Zhangfeng; Wen, Weiping; Lei, Wenbin

    2016-01-01

    Abstract This study aims to analyze the postsurgical health-related quality of life (HRQOL) and quality of voice (QOV) of patients with laryngeal carcinoma with an expectation of improving the treatment and HRQOL of these patients. Based on the collection of information of patients with laryngeal carcinoma regarding clinical characteristics (age, TNM stage, with or without laryngeal preservation and/or neck dissection, with or without postoperative irradiation and/or chemotherapy, etc.), QOV using Voice Handicap Index (VIH) scale and HRQOL using EORTC QLQ-C30 and EORTCQLQ-H&N35 scales, the differences of postsurgical HRQOL related to their clinical characteristics were analyzed using univariate nonparametric tests, the main factors impacting the postsurgical HRQOL were analyzed using regression analyses (generalized linear models) and the correlation between QOV and HRQOL analyzed using spearman correlation analysis. A total of 92 patients were enrolled in this study, on whom the use of EORTC QLQ-C30, EORTC QLQ-H&N35 and VHI scales revealed that: the differences of HRQOL were significant among patients with different ages, TNM stages, and treatment modalities; the main factors impacting the postsurgical HRQOL were pain, speech disorder, and dry mouth; and QOV was significantly correlated with HRQOL. For the patients with laryngeal carcinoma included in our study, the quality of life after open surgeries were impacted by many factors predominated by pain, speech disorder, and dry mouth. It is suggested that doctors in China do more efforts on the patients’ postoperative pain and xerostomia management and speech rehabilitation with the hope of improving the patients’ quality of life. PMID:26735538

  12. Analysis of Postsurgical Health-Related Quality of Life and Quality of Voice of Patients With Laryngeal Carcinoma.

    Science.gov (United States)

    Luo, Jie; Wu, Jieli; Lv, Kexing; Li, Kaichun; Wu, Jianhui; Wen, Yihui; Li, Xiaoling; Tang, Haocheng; Jiang, Aiyun; Wang, Zhangfeng; Wen, Weiping; Lei, Wenbin

    2016-01-01

    This study aims to analyze the postsurgical health-related quality of life (HRQOL) and quality of voice (QOV) of patients with laryngeal carcinoma with an expectation of improving the treatment and HRQOL of these patients. Based on the collection of information of patients with laryngeal carcinoma regarding clinical characteristics (age, TNM stage, with or without laryngeal preservation and/or neck dissection, with or without postoperative irradiation and/or chemotherapy, etc.), QOV using Voice Handicap Index (VIH) scale and HRQOL using EORTC QLQ-C30 and EORTCQLQ-H&N35 scales, the differences of postsurgical HRQOL related to their clinical characteristics were analyzed using univariate nonparametric tests, the main factors impacting the postsurgical HRQOL were analyzed using regression analyses (generalized linear models) and the correlation between QOV and HRQOL analyzed using spearman correlation analysis. A total of 92 patients were enrolled in this study, on whom the use of EORTC QLQ-C30, EORTC QLQ-H&N35 and VHI scales revealed that: the differences of HRQOL were significant among patients with different ages, TNM stages, and treatment modalities; the main factors impacting the postsurgical HRQOL were pain, speech disorder, and dry mouth; and QOV was significantly correlated with HRQOL. For the patients with laryngeal carcinoma included in our study, the quality of life after open surgeries were impacted by many factors predominated by pain, speech disorder, and dry mouth. It is suggested that doctors in China do more efforts on the patients' postoperative pain and xerostomia management and speech rehabilitation with the hope of improving the patients' quality of life. PMID:26735538

  13. Health-related quality of life as a predictor of mortality in patients on peritoneal dialysis1

    Science.gov (United States)

    de Oliveira, Marília Pilotto; Kusumota, Luciana; Haas, Vanderlei José; Ribeiro, Rita de Cássia Helú Mendonça; Marques, Sueli; Oller, Graziella Allana Serra Alves de Oliveira

    2016-01-01

    Objective: to characterize deaths that occurred, and the association between socio-demographic, clinical, laboratory variables and health-related quality of life and the outcome of death in patients on peritoneal dialysis, over a two year period after an initial assessment. Method: observational, prospective population study with 82 patients on peritoneal dialysis. The instruments used for the first stage of data collection were the mini-mental state examination, a sociodemographic, economic, clinical and laboratory questionnaire and the Kidney Disease and Quality of Life-Short Form. After two years, data for characterization and occurrence of death in the period were collected. The relative risk of death outcome was calculated through statistical analysis; the risk of death was estimated by the survival Kaplan-Meier curve, and determined predictors of death by the Cox Proportional Hazards Model. Results: of the 82 original participants, 23 had as an outcome death within two years. The increased risk for the outcome of death was associated with a lower mean score of health-related quality of life in the physical functioning domain. Conclusion: the worst health-related quality of life in the physical functioning domain, could be considered a predictor of death. PMID:27192413

  14. Evaluation of Health-Related Quality of Life among Tuberculosis Patients in Two Cities in Yemen

    Science.gov (United States)

    Jaber, Ammar Ali Saleh; Khan, Amer Hayat; Syed Sulaiman, Syed Azhar; Ahmad, Nafees; Anaam, Mohamed Saif

    2016-01-01

    Background The health-related quality of life (HRQoL) of Tuberculosis (TB) patients is important because it directly influences the outcome of TB patients in several aspects. The current study aims to evaluate and to find the factors influencing the HRQoL of TB patients in two major TB-prevalent cities (Taiz and Alhodidah) in Yemen. Methods A prospective study was conducted, and all TB patients meeting the HRQoL criteria were asked to complete the HRQoL SF-36 survey. The records of TB patients were examined for disease confirmation, and a follow-up was consequently performed for patients during treatment between March 2013 and February 2014 in Taiz and Alhodidah Cities. HRQol scores were calculated by using QM scoring software version 4.5, in which the physical component score (PCS) and mental component score (MCS) were obtained. The scores obtained between 47–53 normal based score (NBS) were considered equivalent to the US normal score. Low scores indicate the poor health situation of TB patients Results A total of 243 TB patients enrolled in the study at the beginning of the treatment. A total of 235 and 197 TB patients completed the questionnaire at the end of the intensive phase (I.P.) and continuation phase (C.P.), respectively. The final dropout rate was 16.2%. The mean PCS and MCS scores at the beginning of treatment were low, thus showing the poor health situation of TB patients. The mean PCS scores at the beginning of treatment, end of I.P., and end of treatment were (36.1), (44.9), and (48), respectively. Moreover, the mean MCS score at the beginning of treatment, end of I.P., and end of treatment were (35.1), (42.2), and (44.3), respectively. The result shows that significant increases are observed at the end of I.P. for PCS and MCS because of the treatment and slight changes at the end of C.P. Despite this finding, the MCS score remains below the normal range (47), thus indicating a significant risk of depression among TB patients. Furthermore

  15. Parental Anxiety and Quality of Life of Epileptic Children

    Institute of Scientific and Technical Information of China (English)

    YONG LI; CHENG-YE JI; JIONG QIN; ZHI-XIANG ZHANG

    2008-01-01

    Objective To investigate the prevalence of parental anxiety associated with epileptic children, and to explore whether and how this specific condition affects children's quality of life (QOL), and what are the significant determinants for parental anxiety. Methods Three hundred and forty parents whose children were affected with known epilepsy were enrolled in the study. Questionnaires for quality of life in childhood epilepsy (QOLCE), and hospital anxiety and depression (HAD) of parents were used to collect demographic data of both children and their parents, as well as clinical manifestations of epilepsy and family status. Results Parental anxiety (of any severity) was observed in 191 subjects at interview, giving a prevalence rate of 56.2%. Of the 191 subjects, 18.5% reported mild anxiety, 24.4% moderate anxiety, and 13.2% severe anxiety. Factors associated with parental anxiety included frequency of seizure in children, average monthly income per person and parents' knowledge about epilepsy (P<0.05). Parental anxiety significantly (P=0.000) correlated with quality of life of children with epilepsy. Conclusion Parents of children with epilepsy are at high risk of having anxiety. Factors associated with parental anxiety originate both from children and from parents. Parental anxiety is significantly related with children's QOL. It is important for experts concerned to recognize such a relationship to improve the QOL of children and their parents.

  16. Validation of a new tool to assess health-related quality of life in psoriasis: the PSO-LIFE questionnaire

    OpenAIRE

    Dauden Esteban; Herrera Enrique; Puig Lluis; Sánchez-Carazo José; Toribio Jaime; Caloto Ma; Nocea Gonzalo; Roset Montse; Lara Nuria

    2012-01-01

    Abstract Background Several questionnaires have been used to measure health related quality of life (HRQoL) in patients with psoriasis, few have been adapted for use in Spain; none of them was developed specifically for the Spanish population. The purpose of the study was to validate and assess the sensitivity to change of a new questionnaire to measure HRQOL in patients with psoriasis (PSO-LIFE). Methods Observational, prospective, multicenter study performed in centers around Spain. Patient...

  17. Validation of Chinese Version of Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (Chi-PCOSQ)

    OpenAIRE

    Lin, Chung-Ying; Ou, Huang-tz; Wu, Meng-Hsing; Chen, Pei-Chi

    2016-01-01

    Objectives To evaluate the responsiveness, longitudinal validity, and measurement invariance of the Chinese version of the Polycystic Ovary Syndrome Health-related Quality of Life Questionnaire (Chi-PCOSQ). Research Design and Method This prospective study was conducted in a medical center in southern Taiwan. 102 women aged 18–45 years and diagnosed with PCOS were enrolled. Objective indicators for clinical changes of PCOS included assessing the 2-hour glucose and insulin levels before and af...

  18. Participation as an outcome measure in psychosocial oncology: content of cancer-specific health-related quality of life instruments

    OpenAIRE

    van der Mei, Sijrike F.; Dijkers, Marcel P. J. M.; Heerkens, Yvonne F

    2011-01-01

    Purpose To examine to what extent the concept and the domains of participation as defined in the International Classification of Functioning, Disability and Health (ICF) are represented in general cancer-specific health-related quality of life (HRQOL) instruments. Methods Using the ICF linking rules, two coders independently extracted the meaningful concepts of ten instruments and linked these to ICF codes. Results The proportion of concepts that could be linked to ICF codes ranged from 68 to...

  19. Effectiveness of teleassistance on the improvement of health related quality of life in people with neuromuscular diseases

    OpenAIRE

    Oscar Martínez; Amaia Jometón; Esther Lázaro; Imanol Amayra; Juan Francisco López-Paz; Manuel Pérez; Patricia Caballero; Luís De Nicolás; Alberto Lasa; Jorge Roldán; Natalia Martín; Joseba Bárcena; Luís Varona

    2012-01-01

    Background Neuromuscular diseases are a group of pathologies characterized by the progressive loss of muscular strength, atrophy or hypertrophy, fatigue, muscle pain and degeneration of the muscles and the nerves controlling them (The French Muscular Dystrophy Association, 2004). Perceived isolation and health related quality of life are affected in the majority of cases due to the illness chronicity. Internet, and in this way, the use of chat and videoconferencing programs, is an alternative...

  20. Defensive coping and health-related quality of life in chronic kidney disease: a cross-sectional study

    OpenAIRE

    Ikonomou Margarita; Damigos Dimitrios; Skapinakis Petros; Kaltsouda Anna; Kalaitzidis Rigas; Mavreas Venetsanos; Siamopoulos Kostas C

    2011-01-01

    Abstract Background Coping with the stresses of chronic disease is considered as a key factor in the perceived impairment of health related quality of life (HRQL). Little is known though about these associations in chronic kidney disease (CKD). The present study aimed to investigate the relationship of defensive coping and HRQL among patients in different CKD stages, after adjusting for psychological distress, sociodemographic and disease-related variables. Methods The sample consisted of 98 ...

  1. Effectiveness of Mindfulness-Based Stress Reduction Intervention for Health-Related Quality of Life in Drug-Dependent Males

    OpenAIRE

    Hosseinzadeh Asl, Navid Reza; Hosseinalipour, Fattaneh

    2014-01-01

    Background: Nowadays drug dependence has become one of the main concerns worldwide. Indeed, drug dependence and abuse have become personal, social and, health problems that intensively threat human resources. Objectives: This study aimed to examine the effect of mindfulness-based stress reduction (MBSR) on health-related quality of life (HRQOL) in drug-dependent males. Patients and Methods: An experimental research with pretest/posttest design and a control group was conducted on 49 drug-depe...

  2. Evaluating change in health-related quality of life in adult rhinitis: Responsiveness of the Rhinosinusitis Disability Index

    OpenAIRE

    Katz Patricia P; Chen Hubert; Shiboski Stephen; Blanc Paul D

    2005-01-01

    Abstract Background The Rhinosinusitis Disability Index (RSDI) is a validated measure of health-related quality of life (HRQL) in rhinitis. Responsiveness of the RSDI to changes in health status over time has not been described. Methods We studied adults with a self-reported physician diagnosis of rhinitis identified through a national telephone survey. HRQL was assessed at baseline and at 24 months using the RSDI. Symptom severity, physical health status (SF-12 PCS), psychological mood (CES-...

  3. "Behavior, Metabolic Control and Health-related Quality of Life in Diabetic Patients at Bandar Abbas Diabetic Clinic"

    Directory of Open Access Journals (Sweden)

    T Aghamollaei

    2003-09-01

    Full Text Available Diabetes is a chronic disease of lifelong duration, and its management requires a fundamental change in the patient’s lifestyle. The aims of this study were to determine behaviors of diabetic patients in relation to management of their disease, assess metabolic control and health-related quality of life of them. The target population was type 2 diabetic patients and a cross-sectional approach was used. We studied 80 randomly chosen patients. To determine behaviors of patients, data was collected using an interview schedule. Metabolic control was assessed by measuring glycosylated hemoglobin (HBA1c, and health-related quality of life was measured by means of WHOQOL-BREF questionnaire. The majority of patients had good compliance with adherence to the prescribed medicines (65% always and 35%often and foot care practices (82.5%. However, only 6.3% of them administered self-monitoring blood glucose and 38.8% complied with dietary regimen always. Among smokers, 13.8% stopped smoking after being diagnosed with the disease. The mean HBA1c in the whole patient group was 9.25 ± 1.06 and it ranged from 6.9 to 12.9 and only 2.5% of them had optimum control. The mean rating of health-related quality of life in all scales varied between 55.67 and 63.75(maximum score: 100. The highest rated mean score was for physical health and the lowest was for psychological. It is recommended that every effort be made to initiate and promote behavioral change and improve metabolic control in diabetic patients. To achieve this, an appropriate patient’s education program should be planned and future research is needed to reveal determinants of compliance behavior and factors associated with metabolic control and health-related quality of life in diabetic patients.

  4. Assessing health-related quality of life in COPD: comparing generic and disease-specific instruments with focus on comorbidities

    OpenAIRE

    Wacker, Margarethe E.; Jörres, Rudolf A.; Karch, Annika; Wilke, Sarah; Heinrich, Joachim; Karrasch, Stefan; Koch, Armin; Schulz, Holger; Watz, Henrik; Leidl, Reiner; Vogelmeier, Claus; Holle, Rolf; ,

    2016-01-01

    Background Chronic Obstructive Pulmonary Disease (COPD) influences different aspects of patient’s health-related quality of life (HRQL). While disease-specific HRQL instruments focus on symptoms and functional impairments, generic instruments cover a broader view on health. This study compares the generic EQ-5D-3 L and two disease-specific questionnaires (St.-George’s Respiratory Questionnaire (SGRQ-C), COPD Assessment Test (CAT)) in a comprehensive spectrum of COPD disease grades with partic...

  5. Health-related quality of life measurement in pediatric clinical practice: An appraisal and precept for future research and application

    OpenAIRE

    Lane Mariella M; Burwinkle Tasha M; Varni James W

    2005-01-01

    Abstract Health-related quality of life (HRQOL) measurement has emerged as an important health outcome in clinical trials, clinical practice improvement strategies, and healthcare services research and evaluation. HRQOL measures are also increasingly proposed for use in clinical practice settings to inform treatment decisions. In settings where HRQOL measures have been utilized with adults, physicians report such measures as useful, some physicians alter their treatment based on patient repor...

  6. Evaluation of relationship between oral health-related quality of life and occlusion traits among female adolescents

    OpenAIRE

    Fahimeh Farzanegan; Farzin Heravi; Aidin Sooratgar; Parisa Dastmalchi

    2014-01-01

    Background: The aim of this study was to determine the impact of malocclusions on oral health-related quality of life (OHRQOL) among female adolescents. Materials and Methods: This is an observational cross-sectional descriptive study. A total of 129 female students with age ranges between 14 and 17 years old were randomly selected from Mashhad (Iran) high schools and were asked to fill out an OHRQOL questionnaire included in four parts: Oral symptoms, functional limitations, emotional we...

  7. Impact of removable dentures on oral health-related quality of life among elderly adults in Taiwan

    OpenAIRE

    Yen, Yea-Yin; Lee, Huey-Er; Wu, Yi-Min; Lan, Shou-Jen; Wang, Wen-Chen; Du, Je-Kang; Huang, Shun-Te; Hsu, Kun-Jung

    2015-01-01

    Background Although the use of removable dentures can improve oral function and esthetics for elderly people, compared to those who do not wear removable dentures, those wearing removable dentures could have worse oral health related-quality of life (OHRQoL). Additional information is required to assess which factors related to denture wearing influence the OHRQoL of elderly individuals. The purpose of this study is to evaluate the association between denture wearing and OHRQoL in a sample of...

  8. Stress and health related quality of life of Nepalese students studying in South Korea: A cross sectional study

    OpenAIRE

    Bhandari Pratibha

    2012-01-01

    Abstract Background In recent years there has been a growing trend among students to travel for educational purposes to other countries where there is the possibility of experiencing considerable amounts of stress affecting their physical and mental functioning. The aims of the current study were to investigate the health related quality of life (HRQOL) of Nepalese students studying in South Korea to explore the relationship between HRQOL and perceived and acculturative stress, and to identif...

  9. Do relative socioeconomic deprivations impact on subjective health-related quality of life and behaviors among adolescents?

    OpenAIRE

    Chau, Nearkasen; Baumann, Michèle

    2012-01-01

    Socioeconomic deprivations include relative parent-education, family structure, nationality, parentoccupation and income that could impact on subjective well-being among adolescents which then persists in adulthood. In an early adolescence context, this study assessed the associations of the previous factors with subjective health-related quality of life (QoL) and behaviors. Methods: Questionnaires were completed by 1559 middle-school adolescents from north-eastern France (mean age 13.5 (SD 1...

  10. Effect of upper limb, lower limb and combined training on health-related quality of life in COPD

    OpenAIRE

    Subin,; Rao Vaishali; Prem V; Sahoo

    2010-01-01

    Objectives: To study the effect of unsupported upper limb and lower limb exercise training and their combined influence on the exercise performance and health-related quality of life in COPD patients. Materials and Methods: Thirty patients were randomly assigned to one of the three groups, through block randomization. Of the three groups, group A received upper limb training, group B received lower limb training, and group C received both upper and lower limb training. Patients in group A,...

  11. Identifying key domains of health-related quality of life for patients with Chronic Obstructive Pulmonary Disease: the patient perspective

    OpenAIRE

    Paap, Muirne C S; Bode, Christina; Lenferink, Lonneke I.M.; Groen, Lianne C; Terwee, Caroline B.; Ahmed, Sara; Eilayyan, Owis; Palen, van der, Job

    2014-01-01

    Background Numerous instruments are available to measure health-related quality of life (HRQoL) in patients with Chronic Obstructive Pulmonary Disease (COPD), covering a wide array of domains ranging from symptoms such as dyspnea, cough and wheezing, to social and emotional functioning. Currently no information or guide is available yet to aid the selection of domains for a particular study or disease population. The aim of this paper is to identify which domains of HRQoL are most important w...

  12. Health related quality of life in people with multiple sclerosis: the role of coping, social participation and self-esteem

    OpenAIRE

    Mikula, Pavol

    2014-01-01

    Multiple sclerosis (MS) is the most common neurological disease with disabling consequences that occurs in young adults. Symptoms of MS are responsible for high levels of stress and low levels of overall health-related quality of life (HRQoL). In this dissertation we aimed at gaining insight into the associations between physical and psychosocial factors and HRQoL in order to identify areas that could benefit from intervention. We found that problem-focused coping, emotion-focused coping and ...

  13. Old Age Homes: Reasons for Admission and the Assessment of Health-Related Quality of Life of Inmates

    OpenAIRE

    Sanjay Dixit, S.B.Bansal, Sonal Banzal, Roshini Saleem Raja, Shivani Dua, Rudri Agrawal

    2015-01-01

    "Background: Aging is a normal phenomenon, and there had been a demographic transition which has led to the continuous increase in elderly population. As this group of people is more vulnerable to various health problems, therefore a study was carried out with following objec-tives. Objectives: To study the reasons responsible for elderly opting for old age homes and Health relat-ed quality of life (HRQOL) of people living in old age homes. Methods: A cross sectional study was do...

  14. Recreational Physical Activity Ameliorates Some of the Negative Impact of Major Depression on Health-Related Quality of Life

    OpenAIRE

    ScottBurtonPatten

    2013-01-01

    Background: Major depressive episodes (MDEs) have a negative effect on health-related quality of life (HRQoL). The objective of this study was to determine whether recreational physical activity can ameliorate some of this negative impact. Methods: The data source for the study was the Canadian National Population Health Survey (NPHS). The NPHS is a longitudinal study that has collected data from a representative cohort of 15,254 community residents. Sixteen years of follow-up data are ...

  15. Assessment of the Psychosocial Predictors of Health-Related Quality of Life in a PTSD Clinical Sample

    OpenAIRE

    NACHAR, NADIM; Guay, Stéphane; Beaulieu-Prévost, Dominic; Marchand, André

    2013-01-01

    Although a wide array of the scientific literature explores the links between posttraumatic stress disorder (PTSD) symptoms, coping strategies, and social support and health-related quality of life (HRQoL) as an outcome variable, their connections remain unclear. It is unknown whether PTSD symptom severity, coping strategies, and social support explain each a unique portion of variance of HRQoL of individuals with PTSD. In the current study, based on pretreatment results of a broader study as...

  16. Health-Related Quality of Life in Breast Cancer Patients with Lymphedema Who Survived More than One Year after Surgery

    OpenAIRE

    Lee, So Hyun; Min, Yu-Sun; Park, Ho Yong; Jung, Tae-Du

    2012-01-01

    Purpose To identify the influence of lymphedema on health-related quality of life (HRQOL) more than 1 year after breast cancer surgery. Methods Ninety-six breast cancer patients who survived more than 1 year after surgery and 104 members of the general population were recruited. Patients were divided into 2 groups according to the presence of lymphedema. HRQOL was evaluated with the Short-Form 36-Item Health Survey. Results There were no statistically significant differences in any scales bet...

  17. Epidemiology, health-related quality of life and economic burden of binge eating disorder: a systematic literature review

    OpenAIRE

    Ágh, Tamás; Kovács, Gábor; Pawaskar, Manjiri; Supina, Dylan; Inotai, András; Vokó, Zoltán

    2015-01-01

    Purpose To perform a systematic review on the epidemiology, the health-related quality of life (HRQoL) and economic burden of binge eating disorder (BED). Methods A systematic literature search of English-language articles was conducted using Medline, Embase, PsycINFO, PsycARTICLES, Academic Search Complete, CINAHL Plus, Business Source Premier and Cochrane Library. Literature search on epidemiology was limited to studies published between 2009 and 2013. Cost data were inflated and converted ...

  18. Profile of health-related quality of life outcomes after liver transplantation: univariate effects and multivariate models

    OpenAIRE

    Russell, R. T.; Feurer, I. D.; Wisawatapnimit, P.; Lillie, E. S.; Castaldo, E. T.; Wright Pinson, C.

    2008-01-01

    Aim. To test the effects of pre- and post-transplant clinical covariates on post-transplant health-related quality of life (HRQOL) score profiles in liver transplant recipients. Material and methods. HRQOL was measured before and after transplantation using the SF-36® Health Survey. Clinical data [diagnosis, model of end-stage liver disease (MELD) score, post-transplant rejection and infection episodes], pre-transplant functional performance (FP), and demographics were collected. Multivariate...

  19. Grass pollen allergy in children and adolescents-symptoms, health related quality of life and the value of pollen prognosis

    OpenAIRE

    Kiotseridis, Hampus; Cilio, Corrado M.; Bjermer, Leif; Tunsäter, Alf; Jacobsson, Helene; Dahl, Åslög

    2013-01-01

    Introduction An association between pollen count (Poaceae) and symptoms is well known, but to a lesser degree the importance of priming and lag effects. Also, threshold levels for changes in symptom severity need to be validated. The present study aims to investigate the relationship between pollen counts, symptoms and health related quality of life (HRQL), and to validate thresholds levels, useful in public pollen warnings. Material and methods Children aged 7–18 with grass pollen allergy fi...

  20. Co-morbidities are the key nominators of the health related quality of life in mild and moderate COPD

    OpenAIRE

    Koskela, Jukka; KilpelÀinen, Maritta; Kupiainen, Henna; Mazur, Witold; Sintonen, Harri; Boezen, Marike; Lindqvist, Ari; Postma, Dirkje,; Laitinen, Tarja

    2014-01-01

    Abstract Background Co-morbidities are common in chronic obstructive pulmonary disease (COPD). We assessed the contribution of common co-morbidities on health related quality of life (HRQoL) among COPD patients. Methods Using both generic (15D) and respiratory-specific (AQ20) instruments, HRQoL was assessed in a hospital based COPD population (N = 739, 64% male...

  1. "Behavior, Metabolic Control and Health-related Quality of Life in Diabetic Patients at Bandar Abbas Diabetic Clinic"

    OpenAIRE

    T Aghamollaei; H. Eftekhar; Shojaeizadeh, D; K Mohammad; M Nakhjavani; F Ghofrani Pour

    2003-01-01

    Diabetes is a chronic disease of lifelong duration, and its management requires a fundamental change in the patient’s lifestyle. The aims of this study were to determine behaviors of diabetic patients in relation to management of their disease, assess metabolic control and health-related quality of life of them. The target population was type 2 diabetic patients and a cross-sectional approach was used. We studied 80 randomly chosen patients. To determine behaviors of patients, data was collec...

  2. Health-related quality of life and physical activity in persons at high risk for type 2 diabetes

    OpenAIRE

    Häkkinen, Arja; Kukka, Anna; Onatsu, Tanja; Järvenpää, Salme; Heinonen, Ari; Tomas-Carus, Pablo; Kallinen, Mauri

    2009-01-01

    Purpose. The aim of this study was to compare the health-related quality of life (HRQOL) of persons at risk for type 2 85 diabetes to that of the Finnish general population. In addition, the associations between physical activity and HRQOL at-risk persons were studied. Methods. One hundred thirty-two at-risk persons were recruited from health care centres in Central Finland. Participants filled out questionnaires including demographic characteristics, HRQOL (SF-36), frequency of vigorous phys...

  3. The health related quality of life of the employees in the Greek hospitals: assessing how healthy are the health workers.

    OpenAIRE

    Aga Jenny; Houliara Lambrini; Yfantopoulos Yannis; Demakakos Panayotes TH; Tountas Yannis; Pavi Elpida

    2003-01-01

    Abstract Background The main aim of the study was to assess the health status and health related quality of life of the personnel of the Hellenic Network of Health Promotion Hospitals. The instrument used was SF-36. An additional aim was to contribute to the validation of the SF-36. Methods The study instrument was administered to 347 randomly selected employees from seven hospitals within major Athens area. Completed questionnaire were obtained by 292 employees. The statistical significance ...

  4. Health Related Quality of Life and Urinary Incontinence in Women with Overweight and Obesity in Bucaramanga, Colombia

    OpenAIRE

    Lina María Carreño; Adriana Angarita-Fonseca; Alba Lucía Pinto; Alejandra Nancy Delgado; Lina Marcela García

    2015-01-01

    Abstract: Objective: To determine the association between quality of life health-related (HRQL) and urinary incontinence (UI) in a population of overweight women in the urban area of Bucaramanga, Colombia. Materials and methods: An analytic cross-sectional study was conducted in March and May 2012. The sample consisted of 63 randomly selected women; median age was 46 years with a minimum of 18 and maximum of 65 years, 76 % were overweight, and 24 % obese. We assessed the HRQL with the SF-...

  5. Association between Cardiorespiratory Fitness and Health-Related Quality of Life among Patients at Risk for Cardiovascular Disease in Uruguay

    OpenAIRE

    Clennin, Morgan N.; Payne, Jonathan P.W.; Rienzi, Edgardo G.; Lavie, Carl J.; Blair, Steven N.; Pate, Russell R.; Sui, Xuemei

    2015-01-01

    To date, few studies have examined the relationship between cardiorespiratory fitness (CRF) and health-related quality of life (HRQoL) in populations at high risk for developing cardiovascular disease (CVD). Purpose To examine the association between objectively measured CRF and physical and mental components of HRQoL in a Uruguayan cohort at risk for developing CVD. Methods Patient data records from 2002–2012 at the Calidad de Vida Center were examined. To assess CRF, participants performed ...

  6. The impact of severe sepsis on health-related quality of life: A long-term follow-up study

    OpenAIRE

    Hofhuis, Jose; Spronk, Peter; Stel, Henk; Schrijvers, Augustinus; Rommes, Johannes Hans; Bakker, Jan

    2008-01-01

    textabstractBACKGROUND:: Severe sepsis is frequently complicated by organ failure and accompanied by high mortality. Patients surviving severe sepsis can have impaired health-related quality of life (HRQOL). The time course of changes in HRQOL in severe sepsis survivors after discharge from the intensive care unit (ICU) and during a general ward stay have not been studied. METHODS:: We performed a long-term prospective study in a medical-surgical ICU. Patients with severe sepsis (n = 170) adm...

  7. Health-related quality of life of community-dwelling stroke survivors: a comparison of fallers and non-fallers

    OpenAIRE

    Hong, Eunkyoung

    2015-01-01

    [Purpose] The purpose of this study was to compare the health-related quality of life (HRQOL) of stroke survivors between fallers and non-fallers. [Subjects] The subjects were community-dwelling stroke patients (n = 4,560) in South Korea. All stroke patients were diagnosed by a doctor. [Methods] This study used raw data from the 2014 Korean Community Health Survey. The survey was conducted from August 16, 2014, to October 31, 2014. Trained surveyors visited households selected from the sample...

  8. New Oral Anticoagulants vs Vitamin K Antagonists: Benefits for Health-Related Quality of Life in Patients with Atrial Fibrillation

    OpenAIRE

    Alegret, Josep M; Viñolas, Xavier; Arias, Miguel A.; Martínez-Rubio, Antoni; Rebollo, Pablo; Ràfols, Carles; Martínez-Sande, José L.

    2014-01-01

    New oral anticoagulants (NOAC) have demonstrated their efficacy as an alternative to vitamin K antagonists (VKA) in the prophylaxis of cardioembolic events in patients with atrial fibrillation (AF). However, evidence on the benefits of NOAC in health-related quality of life (HRQoL) is lacking.We evaluated changes in HRQoL related to oral anticoagulation therapy employing a specific questionnaire in a cohort of 416 patients with AF undergoing electrical cardioversion. In terms of HRQoL, we obs...

  9. Improved Health-Related Quality of Life After Surgical Management of Severe Refractory Constipation-Dominant Irritable Bowel Syndrome

    OpenAIRE

    Lam, Jennifer Y.; Kidane, Biniam; Manji, Farouq; Taylor, Brian M.

    2015-01-01

    Irritable bowel syndrome (IBS) is the most common of the functional gastrointestinal disorders (FGIDs). Despite its prevalence and health-care costs, there are few effective therapies for patients with severe symptoms. Our objective was to determine whether surgical management would improve health-related quality of life (HRQOL) in severe refractory constipation-dominant FGIDs. From 2003 to 2005, 6 patients underwent total colectomy with end ileostomy or primary anastomosis. They completed Sh...

  10. Fatness and fitness: how do they influence health-related quality of life in type 2 diabetes mellitus?

    OpenAIRE

    Wu Albert W; Ouyang Pamela; Bennett Wendy L; Barone Bethany B; Stewart Kerry J

    2008-01-01

    Abstract Objective We examined whether adiposity and fitness explain the decrease in health-related quality of life (HRQOL) associated with type 2 diabetes mellitus. Methods This was a cross-sectional study using baseline data from two exercise training interventions. One study enrolled people with and the other without type 2 diabetes. We assessed aerobic fitness ("fitness") as peak oxygen uptake during treadmill testing, adiposity ("fatness") as percentage of total body fat by dual-energy x...

  11. Health and health-related quality of life in pig farmers carrying livestock-associated methicillin-resistant Staphylococcus aureus.

    Science.gov (United States)

    VAN Cleef, B A G L; VAN Benthem, B H B; Verkade, E J M; VAN Rijen, M M L; Kluytmans-VAN DEN Bergh, M F Q; Graveland, H; Bosch, T; Verstappen, K M H W; Wagenaar, J A; Heederik, D; Kluytmans, J A J W

    2016-06-01

    There is limited knowledge about the effect of livestock-associated methicillin-resistant Staphylococcus aureus (LA-MRSA) carriage on health-related quality of life (QoL). With this study, we explored whether LA-MRSA causes infections or affects health-related QoL in pig farmers. This prospective cohort study surveyed persons working on 49 farrowing pig farms in The Netherlands for 1 year (2010-2011). On six sampling moments, nasal swabs, environmental samples and questionnaires on activities and infections were collected. At the end of the study year, persons were asked about their QoL using the validated SF-36 and EQ-5D questionnaires. Of 120 persons, 44 (37%) were persistent MRSA carriers. MRSA carriage was not associated with infections, use of antimicrobials, healthcare contact and health-related QoL items in univariate or multivariate analysis, most likely due to the 'healthy worker effect'. Despite high carriage rates, the impact of LA-MRSA carriage in this population of relatively healthy pig farmers on health and health-related QoL appears limited; more research is needed for confirmation. PMID:26733049

  12. Effect on health-related quality of life of a multimodal physiotherapy program in patients with chronic musculoskeletal disorders

    Directory of Open Access Journals (Sweden)

    Cuesta-Vargas Antonio Ignacio

    2013-02-01

    Full Text Available Abstract Background Musculoskeletal disorders are major causes of morbidity in the world, and these conditions have a strong negative influence in terms of health-related quality of life. The purpose of this study was to evaluate the effect of an 8-week multimodal physical therapy program on general health state and health-related quality of life in patients with chronic musculoskeletal disorders. Methods There were 244 participants in this prospective cohort analysis with 8-week follow-up. The primary outcome was general health state (physical and mental components, determined with the Short Form-12 Health Survey (SF-12. The secondary outcome was health related quality of life, determined with the EuroQoL-5D and VAS. The intervention was evaluated by comparing pre- and post-outcome measurements. T-tests were performed for paired data. Results Differences were statistically significant for physical health state: +1.68 (p  Conclusions Eight weeks of a Multimodal Physical Therapy Program seemed to moderately enhance the general health state and HRQoL of patients with chronic musculoskeletal diseases. This kind of therapeutic exercise can be recommended to patients with chronic low back pain, chronic neck pain and osteoarthritis, at least in the short term.

  13. Comparing health-related quality of life of employed women and housewives: a cross sectional study from southeast Iran

    Directory of Open Access Journals (Sweden)

    Saravi Fatihe Kerman

    2012-11-01

    Full Text Available Abstract Background Quality of life differs for different people in different situations and is related to one's self-satisfaction with life. Considering the role of women in family and social health and the specific cultural characteristics of our province, we aimed to compare the quality of life of employed women with housewives in Zahedan, Iran. Methods This cross-sectional study was carried out during 2009–2010 in Zahedan, Iran. The sample consisted of 110 housewives and 110 employed women selected randomly from ten health care centers. Health-related quality of life was assessed using the SF-36. Analysis of covariance (ANCOVA was used to compare quality of life in housewives and employed women while controlling for age, education and income. Results The mean (±SD age of participants was 33.87± 8.95 years. Eighty-eight women (40% had a university degree with a mean (±SD official education of 10.8 (±4.9 years. The results indicated that employed women scored higher than housewives in all measures except for physical functioning. The differences were found to be remarkable for vitality, mental health and role emotional. However, after controlling for age, education and family income, none of differences reached significant level. Conclusion After controlling for potential confounders, the findings from this study indicated that there were no significant differences in quality of life between employed women and housewives. However, employed women scored higher on the SF-36, especially on the role emotional, vitality, and mental health. The findings suggest that associations exist between some aspects of health-related quality of life and employment. Indeed improving health-related quality of life among housewives seems essential.

  14. Smoking has a negative impact upon health related quality of life after treatment for head and neck cancer

    DEFF Research Database (Denmark)

    Jensen, Kenneth; Jensen, Anders Bonde; Grau, Cai

    2006-01-01

    To examine the influence of smoking on observer based morbidity scores and patient assessed health related quality of life after treatment for head and neck cancer. The results of EORTC C30 and H&N35 questionnaires and DAHANCA morbidity scores were studied according to smoking status in 114...... recurrence free head and neck cancer patients. In contrast to observer based toxicity scoring, smoking had a significantly negative influence on 20 of the 33 quality of life scales. Previous smokers had quality of life scores in between never smokers and continuous smokers. Smoking after treatment of head...... and neck cancer adversely influenced a wide range of quality of life endpoints. Quitters had better quality of life than patients who continued to smoke after treatment, suggesting that smoking cessation may improve quality of life in addition to reducing the risk of new cancer. Udgivelsesdato: 2007...

  15. Evaluation of differences in health-related quality of life during the treatment of post-burn scars in pre-school and school children

    Directory of Open Access Journals (Sweden)

    Anna Chrapusta

    2014-11-01

    Full Text Available [b]objective[/b]. The aim of the research was an assessment of the differences in the self-evaluation of health-related quality of life during the treatment of post-burn scars on the upper limbs of pre-school and school children. [b]materials and method[/b]. a group of 120 children were examined – 66 boys and 54 girls, divided into a pre-school group of 60 children (average age 4.3 ± 1.7 and a primary school group of 60 children (average age 10.4 ± 1.2. The structured interview and an adopted Visual Analog Anxiety Scale and Visual Analog Unpleasant Events Tolerance Scale were used to evaluate the level of plaster tolerance, and anxiety caused by the removal of dressings during treatment. [b]results[/b]. In the first test, In both groups, a low tolerance was noted to the pressure plaster, with the pre-school aged children obtaining worse results (x=18.9 ± SD 10.16 than those of school age (x=33.65± SD 13,21, regardless of gender. Pre-school children were afraid (x=47.5 ± SD 24.26, while school-aged children were not afraid of having the plaster removed (x=20.5 ± SD 9.46. The differences between the groups were statistically significant. In the fourth and final test on pre-school aged children, the tolerance of plasters had improved (x=23.24 ± SD 15.43 obtaining a value somewhat lower than for school-aged children (32.4 ± SD 6.45, as well as a noted fall in the anxiety level (30.83 ± SD 23.38 with an average value insignificantly higher than that recorded for the children of school age (15.83 ± SD 6.19. [b]conclusions[/b]. The tests confirmed the appearance of differences in the self-evaluation of health-related life quality in pre-school and school-aged children.

  16. Differences in Sleep Quality and Health-Related Quality of Life in Young Adults with Allergies and Asthma and Their Healthy Peers

    Science.gov (United States)

    Molzon, Elizabeth S.; Bonner, Margaret S.; Hullmann, Stephanie E.; Ramsey, Rachelle R.; Suorsa, Kristina I.; Chaney, John M.; Mullins, Larry L.

    2013-01-01

    Objective: The current study examined the relationship between sleep quality and health-related quality of life (HRQOL). Participants: Participants were 501 undergraduate students with allergies (167), asthma + allergies (167), or with no history of a chronic illness (167) completed study measures from August 2011 to April 2012. Methods: The…

  17. Effects of cardiac resynchronization therapy on health-related quality of life in older adults with heart failure

    Directory of Open Access Journals (Sweden)

    Karin F Hoth

    2008-10-01

    Full Text Available Karin F Hoth1,2, Justin Nash3, Athena Poppas4, Kristin E Ellison4, Robert H Paul5, Ronald A Cohen31Division of Psychosocial Medicine, National Jewish Medical and Research Center, Denver, CO, USA; 2Department of Psychiatry, University of Colorado, Denver, CO, USA; 3Department of Psychiatry and Human Behavior; 4Department of Cardiology, Warren Alpert Medical School of Brown University, Providence, RI, USA; 5Department of Psychology, Division of Behavioral Neuroscience, University of Missouri St. Louis, St. Louis, MO, USAAbstract: The aim of the study was to examine changes in health-related quality of life among older adults undergoing cardiac resynchronization therapy (CRT, a pacemaker based intervention for heart failure. Twenty-one patients (mean age = 68; SD = 8 completed measures of cardiovascular health and quality of life prior to and 3-months post-CRT. Following the intervention, patients reported improvements in their perception of their physical functioning (t = 2.8, p < 0.01 and feelings of vitality (t = 2.9, p < 0.01 on the MOS SF-36 Health Survey. Patients improved on objective clinical measures of exercise capacity, cardiac ejection fraction, and ventricular dyssynchrony. Younger patients reported greater improvements in physical functioning and decreases in pain. Higher baseline body mass index was associated with less improvement in physical functioning. Finally, patients with nonischemic heart failure reported greater improvements on multiple subscales of the SF-36 than patients with ischemic heart failure. This preliminary study documented improvements in health-related quality of life following CRT. The findings highlight that specific patient characteristics may be associated with quality of life changes. Future studies will benefit from including quality of life measures that assess multiple health-related domains.Keywords: cardiac resynchronization therapy, heart failure, quality of life

  18. Health-related quality of life in 794 patients with a peripheral facial palsy using the FaCE Scale: a retrospective cohort study.

    NARCIS (Netherlands)

    Kleiss, I.J.; Hohman, M.H.; Susarla, S.M.; Marres, H.A.M.; Hadlock, T.A.

    2015-01-01

    OBJECTIVES: To describe the health-related quality of life of patients visiting a tertiary referral centre for facial palsy, and to analyse factors associated with health-related quality of life, using the FaCE Scale instrument. DESIGN: Retrospective cohort study. SETTING: The Facial Nerve Center at

  19. Importance of factors determining the low health-related quality of life in people presenting with a diabetic foot ulcer

    DEFF Research Database (Denmark)

    Siersma, V; Thorsen, H; Holstein, P E;

    2013-01-01

    To identify the factors responsible for the low health-related quality of life associated with foot ulcers and the relative importance of these factors.......To identify the factors responsible for the low health-related quality of life associated with foot ulcers and the relative importance of these factors....

  20. Health-related quality of life following off-pump versus on-pump coronary artery bypass grafting in elderly moderate to high-risk patients

    DEFF Research Database (Denmark)

    Jensen, Birte Østergaard; Hughes, Pia; Rasmussen, Lars S; Pedersen, Preben Ulrich; Steinbrüchel, Daniel A

    2006-01-01

    Previous trials comparing coronary artery bypass grafting (CABG) with or without extracorporeal circulation have mainly enrolled selected patients at younger age and low risk. Patient-reported health-related quality of life has not been significantly different. We compared health-related quality ...

  1. Sleep Quality Improvement During Cognitive Behavioral Therapy for Anxiety Disorders.

    Science.gov (United States)

    Ramsawh, Holly J; Bomyea, Jessica; Stein, Murray B; Cissell, Shadha H; Lang, Ariel J

    2016-01-01

    Despite the ubiquity of sleep complaints among individuals with anxiety disorders, few prior studies have examined whether sleep quality improves during anxiety treatment. The current study examined pre- to posttreatment sleep quality improvement during cognitive behavioral therapy (CBT) for panic disorder (PD; [Formula: see text]) or generalized anxiety disorder (GAD; [Formula: see text]). Among sleep quality indices, only global sleep quality and sleep latency improved significantly (but modestly) during CBT. Sleep quality improvement was greater for treatment responders, but did not vary by diagnosis. Additionally, poor baseline sleep quality was independently associated with worse anxiety treatment outcome, as measured by higher intolerance of uncertainty. Additional intervention targeting sleep prior to or during CBT for anxiety may be beneficial for poor sleepers. PMID:26244485

  2. Visualization and Dynamics of Multidimensional Health-Related Quality-of-Life-Adjusted Overall Survival: A New Analytic Approach

    OpenAIRE

    Andrei, Adin-Cristian; Grady, Kathleen L.

    2014-01-01

    VesT was a three-armed, placebo-controlled, randomized clinical trial designed to study the effects of 30mg or 60mg/day vesnarinone. Certain contradictory results involving patient health-related quality-of-life (HRQOL) and overall survival (OS) have made a definitive and unified conclusion difficult. To reconcile these findings, we have focused on the HRQOL-adjusted OS, commonly known as QALYs (quality-adjusted life years). Currently, analyses of QALYs incorporate a single HRQOL dimension or...

  3. Health-related quality of life in patients with high-grade gliomas

    DEFF Research Database (Denmark)

    Piil, K; Jakobsen, J; Christensen, Karl Bang;

    2015-01-01

    -being increased significant, indicating a better HRQOL attend of followup. The diagnosis of a HGG leads to an ongoing functional decline measured as a decline of the KPS and a reduced physical activity during leisure time. Supportive care combined with rehabilitative and palliative approaches might well be...... report any depressive symptoms, eight individuals (26.7 %) being depressed at various time points. Among a sub-group of participants who completed all study requirements for the entire study period the level of anxiety decreased significantly during the study. The FACT-Br sub-scale of emotional well...

  4. Children with minimal chance for cure: parent proxy of the child's health-related quality of life and the effect on parental physical and mental health during treatment.

    Science.gov (United States)

    Mandrell, Belinda N; Baker, Justin; Levine, Deena; Gattuso, Jami; West, Nancy; Sykes, April; Gajjar, Amar; Broniscer, Alberto

    2016-09-01

    To assess health-related quality of life (HRQOL) from the time of diagnosis until disease progression in a cohort of children with diffuse intrinsic pontine glioma (DIPG). The assessment was collected from the perspectives of the child and their parents and evaluated the effect of the child's HRQOL on their parents' physical and mental well-being, thus providing insight into the optimal timing of palliative consultation, including anticipatory grief and bereavement services. This longitudinal study assessed 25 parents and their children, ages 2-17 years of age with DIPG across five time-points, baseline and weeks 2, 4, 6, 16, 24. Assessments included the PedsQL 4.0 Core Scales, PedsQL 3.0 Brain Tumor Scale, and Short-Form 36. HRQOL instruments were completed by the child (age ≥5 years) and parent-proxy (ages 2-17 years), with the parent completing the SF-36. Children's reports and parents' proxy of their child's HRQOL indicated poor physical functioning and increased anxiety at the initiation of therapy. A trending improvement in the children's HRQOL was reported by children and parents from baseline to week 6, with a decline at week 16. The childs' parent proxy reported cognitive problems, procedural anxiety and lower overall brain tumor HRQOL were assoicated with poorer self-reported parental mental status. Palliative care consultation should be initiated at the time of diagnosis and is supported in the high physical and emotional symptom burden reported by our patients, with heightened involvement initiated at 16 weeks. Prompt palliative care involvement, mitigating anxiety associated with clinic visits and procedures, management of brain tumor specific symptoms, advanced care planning, anticipatory grief and bereavement services, and care coordination may maximize HRQOL for patients and ensure positive long-term outcomes for parents of children with DIPG. PMID:27344555

  5. A prospective evaluation of short-term health-related quality of life in patients undergoing anterior skull base surgery.

    Science.gov (United States)

    Abergel, Abraham; Fliss, Dan M; Margalit, Nevo; Gil, Ziv

    2010-01-01

    We evaluated the health-related quality of life (QOL) of patients undergoing anterior skull base tumor resection. The Anterior Skull Base Surgery QOL questionnaire, a disease-specific multidimensional instrument dedicated to this population, was used to collect and prospectively analyze demographic, medical, and QOL data on 48 patients. Thirty-nine patients completed the questionnaire preoperatively and at 6 and 12 months postoperatively. Seventeen patients (44%) had malignant histology and 22 (56%) had benign tumors. The overall QOL score decreased significantly at 6 months postoperatively (p base tumor resection returns to baseline by 1 year after surgery. Histology and radiotherapy are significant predictors of health-related QOL in this population. PMID:20592855

  6. Health-related quality-of-life in adolescent idiopathic scoliosis patients 25 years after treatment

    DEFF Research Database (Denmark)

    Simony, Ane; Hansen, Emil Jesper; Carreon, Leah Y;

    2015-01-01

    long-term studies exists, focusing on the health related quality of life. The purpose of this study was to evaluate the long-term health related outcome, in a cohort of AIS patients, treated 25 years ago. METHOD: 219 consecutive patients treated with Boston brace (Brace) or posterior spinal fusion (PSF......) using Harrington- DDT instrumentation between 1983 and 1990 at Rigshospitalet Copenhagen, were invited to participate in a long-term evaluation study. A validated Danish version of the Scoliosis Research Society 22R (SRS22R) and Short Form-36 (SF36v1) were administrated to the patients two weeks before...... the clinical and radiological examination. RESULTS: 159 (72,6 %) patients participated in the clinical follow up and questionnaires, 11 patients participated only in the questionnaires, 8 emigrated, 4 were excluded due to progressive neurological disease and 2 were deceased. The total follow up was...

  7. Can Intensity-Modulated Radiotherapy Preserve Oral Health-Related Quality of Life of Nasopharyngeal Carcinoma Patients?

    International Nuclear Information System (INIS)

    Purpose: To investigate the changes in salivary function and oral health-related quality of life for patients with nasopharyngeal carcinoma treated by intensity-modulated radiotherapy (IMRT). Methods and Materials: A total of 57 patients with early-stage nasopharyngeal carcinoma received IMRT. The parotid and whole saliva flow was measured, and the Medical Outcomes Study 36-item short form, European Organization for Research and Treatment of Cancer Quality of Life questionnaire-C30, European Organization for Research and Treatment of Cancer Quality of Life questionnaire 35-item head-and-neck module, and Oral Health Impact Profile questionnaires were completed at baseline and 2, 6, 12, 18, and 24 months after IMRT. Results: Parotid saliva flow recovered fully after 1 year and maintained. Whole saliva flow recovered partially to 40% of baseline. A general trend of deterioration in most quality of life scales was observed after IMRT, followed by gradual recovery. Persistent oral-related symptoms were found 2 years after treatment. Conclusion: IMRT for early-stage nasopharyngeal carcinoma could only partially preserve the whole salivary function and oral health-related quality of life.

  8. Health-Related Quality of Life in Children and Adolescents with Celiac Disease: From the Perspectives of Children and Parents

    Directory of Open Access Journals (Sweden)

    Ing-Marie Byström

    2012-01-01

    Full Text Available Aim. To examine how celiac children and adolescents on gluten-free diet valued their health-related quality of life, and if age and severity of the disease at onset affected the children’s self-valuation later in life. We also assessed the parents’ valuation of their child’s quality of life. Methods. The DISABKIDS Chronic generic measure, short versions for both children and parents, was used on 160 families with celiac disease. A paediatric gastroenterologist classified manifestations of the disease at onset retrospectively. Results. Age or sex did not influence the outcome. Children diagnosed before the age of five scored higher than children diagnosed later. Children diagnosed more than eight years ago scored higher than more recently diagnosed children, and children who had the classical symptoms of the disease at onset scored higher than those who had atypical symptoms or were asymptomatic. The parents valuated their children’s quality of life as lower than the children did. Conclusion. Health-related quality of life in treated celiac children and adolescents was influenced by age at diagnosis, disease severity at onset, and years on gluten-free diet. The disagreement between child-parent valuations highlights the importance of letting the children themselves be heard about their perceived quality of life.

  9. Can Intensity-Modulated Radiotherapy Preserve Oral Health-Related Quality of Life of Nasopharyngeal Carcinoma Patients?

    Energy Technology Data Exchange (ETDEWEB)

    Pow, Edmond H.N., E-mail: ehnpow@hku.hk [Oral Rehabilitation, University of Hong Kong Faculty of Dentistry, Hong Kong Special Administrative Region (China); Kwong, Dora L.W.; Sham, Jonathan S.T.; Lee, Victor H.F.; Ng, Sherry C.Y. [Department of Clinical Oncology, University of Hong Kong Li Ka Shing Faculty of Medicine, Hong Kong Special Administrative Region (Hong Kong)

    2012-06-01

    Purpose: To investigate the changes in salivary function and oral health-related quality of life for patients with nasopharyngeal carcinoma treated by intensity-modulated radiotherapy (IMRT). Methods and Materials: A total of 57 patients with early-stage nasopharyngeal carcinoma received IMRT. The parotid and whole saliva flow was measured, and the Medical Outcomes Study 36-item short form, European Organization for Research and Treatment of Cancer Quality of Life questionnaire-C30, European Organization for Research and Treatment of Cancer Quality of Life questionnaire 35-item head-and-neck module, and Oral Health Impact Profile questionnaires were completed at baseline and 2, 6, 12, 18, and 24 months after IMRT. Results: Parotid saliva flow recovered fully after 1 year and maintained. Whole saliva flow recovered partially to 40% of baseline. A general trend of deterioration in most quality of life scales was observed after IMRT, followed by gradual recovery. Persistent oral-related symptoms were found 2 years after treatment. Conclusion: IMRT for early-stage nasopharyngeal carcinoma could only partially preserve the whole salivary function and oral health-related quality of life.

  10. Assessment and clinical aspects of health-related quality of life in dialysis patients and patients with chronic kidney disease

    DEFF Research Database (Denmark)

    Molsted, Stig; Prescott, Lotte; Heaf, James;

    2007-01-01

    BACKGROUND/AIMS: It is relevant to investigate health-related quality of life (HRQOL) in dialysis and chronic kidney disease (CKD) patients in order to optimise treatment. The aim of this study was to investigate HRQOL in dialysis and CKD patients, to compare results from patients treated with...... control parameters were measured and the patients completed the questionnaire Kidney Disease Quality Of Life. RESULTS: PD patients rated Dialysis Staff Encouragement and Patient Satisfaction better than HD patients (p< or = 0.05). Dialysis patients scored significant lower than the general population in...... hemodialysis (HD) and peritoneal dialysis (PD) and to investigate the prediction of dialysis quality control parameters (blood hemoglobin, plasma albumin, and Kt/V) and tobacco smoking in disease-specific HRQOL. METHODS: Seventy-one HD, 59 PD, and 63 CKD patients participated in the study. Dialysis quality...

  11. Validation of a specific measure to assess health-related quality of life in patients with schizophrenia and bipolar disorder: the 'Tolerability and quality of life' (TOOL) questionnaire

    OpenAIRE

    Cordero Luis; Rebollo Pablo; Cuervo Jesús; Lauffer Javier; Montejo Angel L; Diez Teresa; Maurino Jorge

    2011-01-01

    Abstract Background Perception of quality of life may differ depending on the perspective. The aim of the study was to assess the psychometric properties of the Spanish version of the 'TOlerability and quality Of Life' (TOOL) questionnaire, a specific self-rated instrument to evaluate the impact of side effects of antipsychotic drugs on health-related quality of life (HRQoL). The questionnaire consists of eight items answered on a four-point Likert scale. Methods A psychometric study was cond...

  12. Relationships among Depression, Anxiety, Sleep, and Quality of Life in Patients with Parkinson's Disease in Taiwan.

    Science.gov (United States)

    Fan, Jun-Yu; Chang, Bao-Luen; Wu, Yih-Ru

    2016-01-01

    The aim of this study was to examine the relationships among depression, anxiety, sleep disturbances, Parkinson's disease (PD) symptoms, PD medications, and health-related quality of life (QOL) and to identify the predictors of health-related QOL in PD patients. To do this, we administered a battery of questionnaires and rating scales (validated Chinese versions), including the Unified Parkinson's Disease Rating Scale, 39-item Parkinson's Disease Questionnaire, Parkinson's Disease Sleep Scale-2, Beck Depression Inventory, and Beck Anxiety Inventory, to 134 patients with PD whose Minimental State Examination scores were ≥24. We found that patients who reported having poorer QOL had longer disease durations, more severe PD symptoms, higher Hoehn and Yahr stages, and higher levodopa dosages, as well as higher levels of anxiety and depression, more sleep disturbances, and poorer overall cognitive statuses. Among these variables, the cognitive status, dependency of activities of daily living, depression, and anxiety were identified as predictors of QOL in PD patients and were all significant and independent factors of poor QOL in PD patients. The clinicians should be aware of the effects of these factors on QOL and attempt to treat comorbid psychiatric conditions to improve the PD patients' QOL. PMID:27293956

  13. Measuring the Effects of Medication Use on Health-Related Quality of Life in Patients with Rheumatoid Arthritis: A Review

    OpenAIRE

    Michael B. Nichol; Ann S. M. Harada

    1999-01-01

    As the treatment of rheumatoid arthritis (RA) moves towards earlier and more consistently maintained therapy, often with highly toxic medications, the importance of assessing patients' health-related quality of life (HR-QOL) is of increasing concern to healthcare providers, insurers and policy-makers. As the course of RA can extend 20 years or more, and as patient involvement in their care and evaluation increases, the goal of therapy should be to work towards the HR-QOL desired by the patien...

  14. Health-related quality of life and cognitive emotion regulation strategies in the unemployed: a cross-sectional survey

    OpenAIRE

    Extremera, Natalio; Rey, Lourdes

    2014-01-01

    Background The loss of one’s job has been conceptualized as a major stressful life event in an adult’s life and has consistently been associated with lower health-related quality of life (HRQoL). The role of cognitive emotion regulation strategies after the experience of stressful events has emerged as an important predictor of adverse psychological and health outcomes. However, the effect of these coping strategies on the HRQoL of unemployed people has not been examined until now. We aimed t...

  15. Measuring and Valuing Health-Related Quality of Life among Children and Adolescents in Mainland China – A Pilot Study

    OpenAIRE

    Xu, Fei; Chen, Gang; Stevens, Katherine; Zhou, HaiRong; Qi, ShengXiang; Wang, Zhiyong; Hong, Xin; Chen, XuPeng; Yang, Huafeng; Wang, Chenchen; Ratcliffe, Julie

    2014-01-01

    Background The Child Health Utility 9D (CHU9D), a new generic preference-based health-related quality of life (HRQoL) instrument, has been validated for use in young people in both the UK and Australia. The main objectives of this study were to examine the feasibility of using a Chinese version of the CHU9D (CHU9D-CHN) to assess HRQoL and to investigate the association of physical activity, homework hours and sleep duration with HRQoL in children and adolescents in Mainland China. Methods Dat...

  16. The impact of health literacy and life style risk factors on health-related quality of life of Australian patients

    OpenAIRE

    Jayasinghe, Upali W; Harris, Mark Fort; Parker, Sharon M.; Litt, John; van Driel, Mieke; Mazza, Danielle; Del Mar, Chris; Lloyd, Jane; Smith, Jane; Zwar, Nicholas; Taylor, Richard; ,

    2016-01-01

    Background Limited evidence exists regarding the relationship between health literacy and health-related quality of life (HRQoL) in Australian patients from primary care. The objective of this study was to investigate the impact of health literacy on HRQoL in a large sample of patients without known vascular disease or diabetes and to examine whether the difference in HRQoL between low and high health literacy groups was clinically significant. Methods This was a cross-sectional study of base...

  17. The Health Utilities Index (HUI®) System for Assessing Health-Related Quality of Life in Clinical Studies

    OpenAIRE

    William J Furlong; Feeny, David H; George W. Torrance; Barr, Ronald D.

    2001-01-01

    Purpose. The paper reviews the Health Utilities Index (HUI®) as a means to describe health status and obtain utility scores reflecting health-related quality of life (HRQL). Materials. The HUI Mark 2 (HUI2) and Mark 3 (HUI3) classification and scoring systems are described. The methods used to estimate multi-attribute utility functions for HUI2 and HUI3 are reviewed. The use of HUI in clinical studies for a wide variety of conditions in a large number of countries is illustrated. Principal Fi...

  18. Lifestyle and health-related quality of life: A cross-sectional study among civil servants in China

    OpenAIRE

    Xu Jun; Qiu Jincai; Chen Jie; Zou Liai; Feng Liyi; Lu Yan; Wei Qian; Zhang Jinhua

    2012-01-01

    Abstract Background Health-related quality of life (HRQoL) has been increasingly acknowledged as a valid and appropriate indicator of public health and chronic morbidity. However, limited research was conducted among Chinese civil servants owing to the different lifestyle. The aim of the study was to evaluate the HRQoL among Chinese civil servants and to identify factors might be associated with their HRQoL. Methods A cross-sectional study was conducted to investigate HRQoL of 15,000 civil se...

  19. Oral health related quality of life in cleft lip and palate patients rehabilitated with conventional prostheses or dental implants

    OpenAIRE

    Papi, Piero; Giardino, Rita; Sassano, Pierpaolo; Amodeo, Giulia; Pompa, Giorgio; Cascone, Piero

    2015-01-01

    Objectives: Cleft lip and/or palate (CLP) is the most common congenital craniofacial abnormality, with a prevalence of 9.92 per 10,000 live births. In treating patients with CLP, oral rehabilitation is definitely a very important phase of the treatment in order to improve the patient's oral health related quality of life (OH-QoL). The aim of this retrospective study is to assess the OH-QoL in patients rehabilitated with different prosthetic options, thus comparing the conventional treatments,...

  20. Insomnia, Health-Related Quality of Life and Health Outcomes in Children: A Seven Year Longitudinal Cohort

    OpenAIRE

    Daniel Combs; Goodwin, James L.; Quan, Stuart F.; Morgan, Wayne J; Safal Shetty; Sairam Parthasarathy

    2016-01-01

    Insomnia is common in children, and is associated with decreased school performance and increased psychopathology. Although adult insomnia is linked to worsened health-related quality of life (HRQOL), there is insufficient data evaluating insomnia and HRQOL in children. We examined the HRQOL and health associations of insomnia in a longitudinal cohort of 194 children (96 girls, age at study start 8.7 ± 1.6 years, age at data analysis 15.0 ± 1.8 years) over 7 years. International Classificatio...

  1. New oral anticoagulants vs vitamin K antagonists: benefits for health-related quality of life in patients with atrial fibrillation.

    Science.gov (United States)

    Alegret, Josep M; Viñolas, Xavier; Arias, Miguel A; Martínez-Rubio, Antoni; Rebollo, Pablo; Ràfols, Carles; Martínez-Sande, José L

    2014-01-01

    New oral anticoagulants (NOAC) have demonstrated their efficacy as an alternative to vitamin K antagonists (VKA) in the prophylaxis of cardioembolic events in patients with atrial fibrillation (AF). However, evidence on the benefits of NOAC in health-related quality of life (HRQoL) is lacking.We evaluated changes in HRQoL related to oral anticoagulation therapy employing a specific questionnaire in a cohort of 416 patients with AF undergoing electrical cardioversion. In terms of HRQoL, we observed a progressive adaptation to treatment with VKA; satisfaction with NOAC remained constant. Older age, higher left ventricular ejection fraction and NOAC were associated with better HRQoL. PMID:24843316

  2. Clinicians' perspectives of health related quality of life (HRQoL) implications of amblyopia: a qualitative study

    OpenAIRE

    Carlton, J.

    2010-01-01

    Aims or Purpose: The health related quality of life (HRQoL) implications of amblyopia and/or its treatment have been reported. However the clinician’s perspective has not previously been explored. The purpose of this study was to explore the HRQoL implications of amblyopia and/or its treatment from a clinician’s perspective. Methods: Three focus group sessions were conducted with practising orthoptists. The transcripts were analysed using “Framework” analysis to identify HRQoL ...

  3. Insomnia, Health-Related Quality of Life and Health Outcomes in Children: A Seven Year Longitudinal Cohort

    OpenAIRE

    Combs, Daniel; Goodwin, James L.; Quan, Stuart F.; Morgan, Wayne J.; Shetty, Safal; Parthasarathy, Sairam

    2016-01-01

    Insomnia is common in children, and is associated with decreased school performance and increased psychopathology. Although adult insomnia is linked to worsened health-related quality of life (HRQOL), there is insufficient data evaluating insomnia and HRQOL in children. We examined the HRQOL and health associations of insomnia in a longitudinal cohort of 194 children (96 girls, age at study start 8.7 ± 1.6 years, age at data analysis 15.0 ± 1.8 years) over 7 years. International Classificatio...

  4. Insomnia, Health-Related Quality of Life and Healthcare Resource Consumption: A Study of Managed-Care Organisation Enrollees

    OpenAIRE

    Hatoum, Hind T; Kong, Sheldon X; Christopher M. Kania; Josephine M. Wong; Mendelson, Wallace B.

    1998-01-01

    Objective: Insomnia is a prevalent sleep complaint which has been reported to be greatly associated with reduced health-related quality of life (HR-QOL) and increased healthcare resource use. This study documents the prevalence of insomnia, and its impact on patients' HR-QOL and healthcare resource use in managed-care settings in the US. Design and Setting: A multi-site survey of 5 American Medical Group Association(R) (AMGA) clinics was conducted. Each clinic mailed questionnaires to 1100 ra...

  5. Testosterone replacement therapy improves the health-related quality of life of men diagnosed with late-onset hypogonadism

    OpenAIRE

    Almehmadi, Yousef; Yassin, Aksam A.; Nettleship, Joanne E.; Saad, Farid

    2015-01-01

    Objectives To test the hypothesis that testosterone replacement therapy (TRT) improves the long-term health-related quality of life (HRQoL) of men with late-onset hypogonadism (LOH), as studies have shown that sub-physiological testosterone levels have a negative impact on psychological (e.g. mood, vitality, libido and sexual interest) and physical features (e.g. erectile function and physical strength), all of which contribute to a sense of well-being. Patients and methods In all, 261 patien...

  6. Adjustment, psychological functioning and health-related quality of life in adults with primary malignant brain tumours

    OpenAIRE

    Baker, Paul

    2015-01-01

    The thesis has been prepared in a paper-based format and includes three papers: Paper 1, a systematic review; Paper 2, an empirical study; and Paper 3, a critical appraisal and reflection on the work.Paper 1 has been prepared for submission to Neuro-Oncology. The paper presents a systematic review of 21 studies concerning the relationships of demographic, clinical and mental health factors on health-related quality of life (HRQoL) and psychological functioning in adults with primary malignant...

  7. Evaluation of health-related quality of life of women living in a city center in the east of Turkey

    OpenAIRE

    ERBAYDAR, Nüket Paksoy; BİLİR, Nazmi; ÖZCEBE, Lütfiye Hilal; VAİZOĞLU, Songül; Aslan, Dilek

    2011-01-01

    To evaluate the health-related quality of life of women living in Van city center by SF-36 and its association with the women's characteristics. Materials and methods: The women (n = 1527) answered a questionnaire through a face-to-face interview, and some measurements were made. The variations of physical component score (PCS) and mental component score (MCS) of SF-36 were investigated by non-parametric tests, and by linear regression analysis. Results: The percentage of early marri...

  8. The Role of Personality and Social Support in Health-Related Quality of Life in Chronic Kidney Disease Patients.

    Directory of Open Access Journals (Sweden)

    Norhayati Ibrahim

    Full Text Available Chronic kidney disease (CKD is commonly associated with various negative health outcomes. The aim of this study was to examine the influence of personality and social support on health-related quality of life in patients with chronic kidney disease. Health-related quality of life (HRQoL is the quality of life studied in relation to health, and it provides important information of patients' coping with their health issues.Participants comprised of 200 patients experiencing various stages of chronic kidney disease. All participants completed the Short-Form 36 (SF-36, Big Five Inventory (BFI and the Medical Outcomes Study (MOS Social Support questionnaires.Participants consisted of 108 males (54.0% and 92 females (46.0% with the mean age of 59.3 years (SD 14.5. Results showed that higher levels of extraversion and lower perceived affectionate social support were associated with higher physical HRQoL, whereas higher levels of neuroticism were associated with poorer mental HRQoL.The current study found that certain personality traits, namely extraversion and neuroticism, were found to be associated with HRQoL. In addition, affectionate social support was also associated with higher HRQoL. Therefore, special attention should be paid to the personality of CKD patients, as well as the type of social support that they have, in planning interventions to improve their health outcomes.

  9. The Relationship Between Health Related Quality of Life and Vertebral Fracture in Postmenopausal Osteoporosis - Original Investigation

    Directory of Open Access Journals (Sweden)

    Selmin Gülbahar

    2007-06-01

    Full Text Available Aim: The aim of this study was to evaluate the relationship between vertebral fracture and quality of life in postmenopausal osteoporotic patients. Osteoporosis is a disease characterized by low bone mass and structural detoriation of bone tissue, leading to bone fragility and increased susceptibility to fractures. Fracture formation is the most important complication of osteoporosis. Vertebral fractures cause back pain, sleep disorders, depression, and incapacity in daily activities and all these entities decrease quality of life. Patients and Methods: Thirty five female patients with postmenopausal osteoporosis were enrolled in this study. Bilaterally dorsal and lumbar spine radiographs were used to investigate the existence of vertebral compression fracture. Anterior, middle and posterior heights of vertebral bodies (T4-L5 have measured on lateral spine radiographs and the number of vertebrae with fracture were determined. Bone mineral density were measured by using Dual Energy X Ray Absorbtiometry (DXA at the lumbar spine (L1-4 and proximal femur. Quality of life was assessed by using Quality of Life Questionnaire of the European Foundation For Osteoporosis (QUALEFFO. Results: The mean number of vertebral fractures was 2.14±2.17. There was a correlation between fractures and quality of life pain, physical function, general health assesment, mental function scores and the total score. No significant correlation was found for social function scores. Moreover a positive relation was detected between number of vertebral fractures and age. When bone mineral density values and quality of life scores of the groups were compared, the group having vertebral fractures had lower density and poorer quality of life scores but no statistically significant difference was detected. Conclusion: Osteoporotic vertebral fractures affect quality of life negatively. We suggest that during the treatment and follow up of patients with osteoporosis, quality of life

  10. Health-Related Quality of Life (HRQOL Measures: There are Still Many Unanswered Questions about Human Life

    Directory of Open Access Journals (Sweden)

    Mayowa Ojo Owolabi

    2008-01-01

    Full Text Available Health-related quality of life (HRQOL measures are used to assess the multifaceted impact of disease, and determine the utility and associated disability. In addition, the impact of medical interventions must be assessed by psychometrically robust HRQOL measures based on a comprehensive and dynamic model. To develop such a model, the concepts of life, its quality, domains, essence, and purpose must be properly and clearly understood. The correct understanding of these entities is specifically important for patient-centered medicine and has universal implications for all fields of human endeavor. Therefore, in order to explore questions about life and quality of life adequately, every necessary field of knowledge should be employed. A multilinguistic and etymological appraisal reveals that life is related to medicine, freedom, being, soul, and spirit, all of which must therefore be considered in its conceptualization.

  11. Empirically Derived Dietary Patterns and Health-Related Quality of Life in the SUN Project

    OpenAIRE

    Cristina Ruano; Patricia Henriquez; Miguel Ángel Martínez-González; Maira Bes-Rastrollo; Miguel Ruiz-Canela; Almudena Sánchez-Villegas

    2013-01-01

    OBJECTIVE: The analysis of dietary patterns has become a valuable tool to examine diet-disease relationships but little is known about their effects on quality of life. Our aim was to ascertain the association between major dietary patterns and mental and physical quality of life after 4 years of follow-up. MATERIALS AND METHODS: This analysis included 11,128 participants from the "Seguimiento Universidad de Navarra" (SUN) cohort. Dietary habits were assessed using a validated food-frequency ...

  12. Empirically Derived Dietary Patterns and Health-Related Quality of Life in the SUN Project

    OpenAIRE

    Ruano, C. (Cristina); Henriquez, P. (Patricia); Martinez-Gonzalez, M. A.; Bes-Rastrollo, M.; M. Ruiz-Canela; Sanchez-Villegas, A.

    2013-01-01

    Objective: The analysis of dietary patterns has become a valuable tool to examine diet-disease relationships but little is known about their effects on quality of life. Our aim was to ascertain the association between major dietary patterns and mental and physical quality of life after 4 years of follow-up. Materials and Methods: This analysis included 11,128 participants from the "Seguimiento Universidad de Navarra" (SUN) cohort. Dietary habits were assessed using a validated food-frequen...

  13. Gender Differences in Health Related Quality of Life among People Living with HIV on Highly Active Antiretroviral Therapy in Mekelle Town, Northern Ethiopia

    OpenAIRE

    2015-01-01

    Background. Health related quality of life (HRQOL) is an important outcome measure for highly active antiretroviral treatment program. In Ethiopia, studies revealed that there are improved qualities of life among adults living with the viruses taking antiretroviral therapy but there is no explicit data showing gender differences in health related quality of life. Aim. To assess gender differences in HRQOL and its associated factors among people living with HIV and on highly active antiretrovi...

  14. Impairments, disabilities and health related quality of life after treatment for breast cancer : a follow-up study 2.7 years after surgery

    NARCIS (Netherlands)

    Rietman, J; Dijkstra, P; Debreczeni, R; Geertzen, J; Robinson, D; de Vries, J

    2004-01-01

    Purpose : The aim of this study was to assess impairments, disabilities and health related Quality of Life (QOL) after treatment of breast cancer and to analyse the relationship between treatment modalities, impairments, disabilities and health related QOL. Method : Fifty-five patients who underwent

  15. The Relationship Between Health Related Quality of Life and Vertebral Fracture in Male Osteoporotic Patients

    Directory of Open Access Journals (Sweden)

    Özlem El

    2005-03-01

    Full Text Available Osteoporosis is the most prevalent metabolic bone disease in older people and osteoporotic fractures can be a major cause of morbidity. Vertebral fractures can adversely affect quality of life by causing pain, reducing physical function and mobility, and affecting activities of daily living.The aim of this study was to evaluate the relationship between vertebral fracture and quality of life in male osteoporotic patients. Fortysix male patients with idiopathic osteoporosis were enrolled in this study. Bilaterally thorasic and lumbar spine radiographs were used to investigate the existence of vertebral compression fracture. Anterior, middle and posterior heights of vertebral bodies (T4-L5 have been measured on lateral spine radiographs and the number of vertebrae with fracture were determined.Bone mineral density was measured by using Dual Energy X Ray Absorbtiometry at the lumbar spine(L1-4 and proximal femur. Quality of life was assessed by using Quality of Life Questionnaire of the European Foundation For Osteoporosis(QUALEFFO. The mean number of vertebral fractures was 2.87±1.85.Patients with vertebral fracture (n=31 had lower physical and social function scores than non-fracture patients (n=14. Pain, general health assessment and mental function scores showed no difference between two groups.There was no correlation between number of fractures and quality of life scores. Osteoporotic vertebral fractures affect quality of life negatively. We suggest that during the treatment and follow up of patients with osteoporosis, quality of life scales should be included in the evaluation.

  16. Empirically derived dietary patterns and health-related quality of life in the SUN project.

    Directory of Open Access Journals (Sweden)

    Cristina Ruano

    Full Text Available OBJECTIVE: The analysis of dietary patterns has become a valuable tool to examine diet-disease relationships but little is known about their effects on quality of life. Our aim was to ascertain the association between major dietary patterns and mental and physical quality of life after 4 years of follow-up. MATERIALS AND METHODS: This analysis included 11,128 participants from the "Seguimiento Universidad de Navarra" (SUN cohort. Dietary habits were assessed using a validated food-frequency questionnaire. Factor analysis was used to derive dietary patterns. Quality of life was measured with the validated Spanish version of the SF-36 Health Survey. RESULTS: Two major dietary patterns were identified, the 'Western' dietary pattern (rich in red meats, processed pastries and fast-food and the "Mediterranean" dietary pattern (high in fruits, vegetables and olive oil. After controlling for confounders, the Western dietary pattern was associated with quality of life in all domains. The magnitude of these differences between the subjects in the highest (quintile 5 and the lowest quintile of adherence to the Western pattern ranged from -0.8 (for mental health to -3.5 (for vitality. On the contrary, the Mediterranean dietary pattern was associated with better quality of life domains: differences ranged from +1.3 (for physical functioning to +3.4 (for vitality when comparing extreme quintiles of adherence. Additional sensitivity analyses did not change the reported differences. CONCLUSIONS: Whereas baseline adherence to a Western dietary pattern was inversely associated with self-perceived quality of life after 4 years of follow-up, baseline adherence to a Mediterranean dietary pattern was directly associated with better scores in quality of life four years later in the SUN Project.

  17. Health-related quality of life after treatment for neoplasia of the major salivary glands: a pilot study.

    Science.gov (United States)

    Breeze, J; Morrison, A; Dawson, D; Tipper, J; Rehman, K; Grew, N; Pigadas, N

    2016-09-01

    Treatment of malignancy of the salivary glands risks damage to the cranial nerves, and clinicians' traditional view has been that this will result in adverse effects on physical function and subsequent health-related quality of life (QoL). Preservation of nerves has been advocated to lessen this impact, but we know of no evidence that sacrifice of the facial nerve has any effect on subsequent QoL. We collected data prospectively before and after operation for all malignancies of the major salivary glands treated over five years using two health-related QoL questionnaires: the University of Washington Quality of Life Questionnaire and the Patient Concerns Inventory. Fifteen of17 eligible patients fulfilled the inclusion criteria by having assessments completed both before and after operation. Scores for QoL after treatment of cancer of the submandibular gland dropped at six months, but had resolved to more than 80% of the pretreatment score by a year, with the exception of the domains taste and saliva. The four patients who had weakness of the facial nerve after treatment had appreciable reductions in the physical function components of the QoL domains, but no significant reduction in the social-emotional domains. Use of the Patient Concerns Inventory enables tailoring of services towards those clinicians who a patient feels are potentially most likely to help alleviate factors that have an adverse effect on QoL. Sacrifice of the facial nerve in malignant parotid gland disease results in a considerable reduction in functional health-related QoL scores. Methods to ensure clearance of the tumour while limiting the effects on facial nerve function should always be considered. PMID:27256797

  18. Spiritual Well-Being and Health-Related Quality of Life in Iranian Adolescent Girls.

    Science.gov (United States)

    Mirghafourvand, Mojgan; Charandabi, Sakineh Mohammad-Alizadeh; Sharajabad, Fariba Alizadeh; Sanaati, Favziye

    2016-05-01

    This study aimed to determine the status of quality of life, spiritual well-being, and their relationship among Iranian adolescent girls. This cross-sectional study was conducted on 520 students using the cluster sampling method. The mean score of quality of life was 59.86 (SD: 12.7) from the possible range of 0-100. The mean score of spiritual well-being was 90.22 (SD: 16.25), ranging from 20 to 120. Multivariate linear regression analysis showed a significant relationship between quality of life and the factors including existential well-being, religious well-being, parents' belief for their children's participation in religious ceremonies, father's education and occupation, father's illness, sufficiency of family income for expenses, and the number of children. Given that spiritual well-being dimensions are among the predictors of quality of life. Thus, it is necessary to find ways to promote spiritual well-being in adolescents and ultimately improve their quality of life. PMID:26787114

  19. The relationship between health-related quality of life, obesity and testosterone levels in older men

    DEFF Research Database (Denmark)

    Glintborg, Dorte; Nielsen, Torben Leo; Wraae, Kristian;

    2014-01-01

    quality of life evaluated by Short-Form 36 (SF-36) is decreased in obesity and hypogonadism, but the importance of regional fat mass is unknown. In the present study, we evaluated associations between SF-36, regional fat deposits and bioavailable testosterone (BioT) in ageing men.......quality of life evaluated by Short-Form 36 (SF-36) is decreased in obesity and hypogonadism, but the importance of regional fat mass is unknown. In the present study, we evaluated associations between SF-36, regional fat deposits and bioavailable testosterone (BioT) in ageing men....

  20. Evaluation of oral health related quality of life in patient with mild periodontitis among young male population of Namakkal district

    Directory of Open Access Journals (Sweden)

    Natarajan Shanmuga Sundaram

    2013-01-01

    Full Text Available Aim: The aim of the study is to assess the impact of oral health related quality of life (QOL on patients presenting for scaling and oral prophylaxis using a the oral health-related quality of life (OHRQL questionnaire. Materials and Methods: This prospective study includes a total of 100 male patients of age group 25-35 years, who visited private clinic in Namakkal district, South India. They were assessed for their perceptions of oral health using OHRQL questionnaire before initial periodontal therapy including scaling and root planning. Results: A total of 100 patients (mean age:29 years participated in the study and completed initial periodontal therapy. Before treatment 98% of the patients perceived that their oral health status impacted on their QOL in one or more ways. Bad breath was the most common complaint. Social well-being, personality and psychological function were identified as compromised OHRQL domains. More than 60% of the patients stated their overall general health is affected by periodontal disease. Conclusion: Periodontitis negatively affected QOL in this Namakkal district population of young male patients with mild periodontitis. Conventional non-surgical periodontal therapy and personality development counseling has a potential to ameliorate patient perceptions of oral health and improve their QOL.

  1. Reliability and validity of the KIDSCREEN-52 health-related quality of life questionnaire in a Greek adolescent population

    Directory of Open Access Journals (Sweden)

    Tzavara Chara

    2012-02-01

    Full Text Available Abstract Background The KIDSCREEN-52 is a worldwide instrument for measuring health-related quality of life (HRQoL in children and adolescents. The aim of this study is to assess reliability and validity of the Greek version of KIDSCREEN. Methods Questionnaires were collected from a representative nationwide sample of 1,194 adolescents aged from 11 to 17 years. Internal consistency reliability was determined by calculation of the Cronbach α coefficient. A confirmatory factor analysis (CFA was conducted in order to test the construct validity of the questionnaire. Validity was further examined by investigating the correlation of KIDSCREEN with the Strengths and Difficulties Questionnaire (SDQ and its association with socioeconomic and health-related factors. Results Internal consistency reliability was accepted with a Cronbach α above 0.73 for all KIDSCREEN dimensions. CFA showed that the ten-dimensional model fitted the data well (root mean square error of approximation (RMSEA = 0.048, comparative fit index (CFI = 0.971 and goodness of fit index (GFI = 0.965. Correlation coefficients between KIDSCREEN and SDQ dimensions were significant. Adolescents of low socioeconomic status reported lower scores in the majority of KIDSCREEN dimensions. Also, adolescents with chronic health problem had poorer quality of life concerning physical well-being and other dimensions of KIDSCREEN. Conclusions The Greek version of KIDSCREEN-52 was found to have satisfied psychometric properties and could be suitable for assessing HRQoL in Greek adolescents.

  2. Health-related quality of life of patients following selected types of lumbar spinal surgery: A pilot study

    Directory of Open Access Journals (Sweden)

    Androwich Ida

    2007-12-01

    Full Text Available Abstract Background Over 500,000 spinal surgeries are performed annually in the United States. Although pain relief and improved health-related quality of life (HRQOL are expectations following lumbar spinal surgery, there is limited research regarding this experience from the individual's perspective. In addition, no studies have examined the HRQOL of persons who have had this surgery using a comprehensive approach. The intent of this study was to address this deficiency by an assessment of both the individual and environmental factors that impact perceived HRQOL using the Wilson and Cleary Model for Health-Related Quality of Life in persons who have undergone lumbar spinal surgery. Methods This was a pilot study of 57 adult patients undergoing elective lumbar spinal surgery for either herniated disk and/or degenerative changes. Individuals completed questionnaires measuring perceived pain, mood, functional status, general health perceptions, social support and HRQOL preoperatively and three months following surgery. Descriptive statistics, dependent t-tests, and MANOVAs were used to describe and compare the differences of the study variables over time. Results Preliminary results indicate overall perceived physical HRQOL was significantly improved postoperatively (t [56] = 6.45, p Conclusion Although perceived physical HRQOL was significantly improved three months postoperatively, fatigue and lack of vigor were issues for subjects postoperatively. Excessive fatigue and low vigor may have implications for successful rehabilitation and return to work for patients following lumbar spinal surgery. Further research is needed with a larger sample size and subgroup analyses to confirm these results.

  3. Oral health-related quality of life and dental implants - preliminary study

    Czech Academy of Sciences Publication Activity Database

    Kříž, P.; Seydlová, M.; Dostálová, T.; Valenta, Zdeněk; Chleborád, K.; Zvárová, Jana; Feberová, J.; Hippmann, R.

    2012-01-01

    Roč. 7, č. 2 (2012), s. 209-215. ISSN 1895-1058 R&D Projects: GA MŠk(CZ) 1M06014 Institutional research plan: CEZ:AV0Z10300504 Keywords : dentistry * implant * quality of life Subject RIV: FF - HEENT, Dentistry Impact factor: 0.262, year: 2012

  4. The role of sociodemographic factors in health - related quality of life of patients with end stage renal disease

    Directory of Open Access Journals (Sweden)

    Paraskevi Theofilou

    2011-01-01

    Full Text Available Background: Renal failure is a chronic disease that can have serious effects on patients’ quality of life (QoL.Objective: Gender, age, education and marital status were investigated in end-stage renal disease patients. Specifically, the relationship of QoL and mental health to sociodemographic variables was examined.Methodology: 144 patients in-centre haemodialysis (HD and continuous ambulatory peritoneal dialysis (CAPD were administered the World Health Organization QoL instrument (WHOQOLBREF, the General Health Questionnaire (GHQ-28, the depression CES-D scale, the State-TraitAnxiety Inventory (STAI and the Multidimensional Health Locus of Control scale (MHLC.Results: Female patients reported lower scores in the psychological and environmental QoL domains and higher scores in the Trait Anxiety measure. Elder patients reported higher scores in the GHQ-28 sub-scale of social dysfunction and in the CES-D depression scale, while less educated patients presented higher scores in the GHQ-28 sub-scales of anxiety/insomnia and severe depression. Divorced/widowed patients presented lower scores in the physical, social and environmental QoL domains and higher scores in the severe depression sub-scale. Regarding health locus of control, females and less educated patients reported higher scores in the attitudinal dimension of chance, while younger patients in the dimension of internal.Conclusions: Findings provide evidence that sociodemographic variables, like being female, older, less educated and divorced/widowed, relate to a more compromised QoL.

  5. Health-Related Quality of Life after surgery for primary advanced rectal cancer and recurrent rectal cancer

    DEFF Research Database (Denmark)

    Thaysen, Henriette Vind; Jess, Per; Laurberg, Søren

    2012-01-01

    Aim: A review of the literature was undertaken to provide an overview of Health-related quality of life (HRQoL) after surgery for primary advanced or recurrent rectal cancer and to outline proposals for future HRQoL studies in this area. Method: A systematic literature search was undertaken. Only...... studies concerning surgery for primary advanced or recurrent rectal cancer and describing methods used for measuring HRQoL were considered. Results Seven studies were identified including two prospective longitudinal, three cross-sectional and two based on qualitative data. Global quality of life...... time of impaired HRQoL and also if this is different after surgery for locally advanced or recurrent disease than after total mesorectal excision used for earlier tumours.. Conclusion Several aspects of HRQoL are impaired for a variable time after treatment for locally advanced or recurrence of rectal...

  6. Disease-specific health-related quality of life instruments for IgE-mediated food allergy

    DEFF Research Database (Denmark)

    Salvilla, S A; Dubois, A E J; Flokstra-de Blok, B M J;

    2014-01-01

    This is one of seven interlinked systematic reviews undertaken on behalf of the European Academy of Allergy and Clinical Immunology as part of their Guidelines for Food Allergy and Anaphylaxis, which focuses on instruments developed for IgE-mediated food allergy. Disease-specific questionnaires are...... significantly more sensitive than generic ones in measuring the response to interventions or future treatments, as well as estimating the general burden of food allergy. The aim of this systematic review was therefore to identify which disease-specific, validated instruments can be employed to enable assessment...... of the impact of, and investigations and interventions for, IgE-mediated food allergy on health-related quality of life (HRQL). Using a sensitive search strategy, we searched seven electronic bibliographic databases to identify disease-specific quality of life (QOL) tools relating to Ig...

  7. Long-Term Health-Related Quality of Life in German Patients with Juvenile Idiopathic Arthritis in Comparison to German General Population.

    Directory of Open Access Journals (Sweden)

    Swaantje Barth

    Full Text Available Aims of the study were to investigate health-related quality of life (HRQOL in adult patients with former diagnosis of Juvenile Idiopathic Arthritis (JIA, to compare their HRQOL with the general population and to identify factors related to a poor outcome.In 2012, a cross-sectional survey was performed by mailing a questionnaire to a large cohort of former and current patients of the German Centre for Rheumatology in Children and Adolescents. Only adult patients (≥18 years with a diagnosis compatible with JIA were included (n = 2592; response 66%. The questionnaire included information about HRQOL (EQ5D, disease-related questions and socio-demographics. Prevalence and 95% confidence intervals (CI of problems with mobility, self-care, usual activities, pain and anxiety/depression were standardized to the German general population. Factors associated with low HRQOL in JIA patients were identified using logistic regression models.Sixty-two percent of the study population was female; age range was 18-73 years. In all dimensions, JIA patients reported statistically significantly more problems than the general population with largest differences in the pain dimension (JIA patients 56%; 95%CI 55-58%; general population 28%; 26-29% and the anxiety/depression dimension (28%; 27-29% vs. 4%; 4-5%. Lower HRQOL in JIA patients was associated with female sex, older age, lower level of education, still being under rheumatic treatment and disability.HRQOL in adult JIA patients is considerably lower than in the general population. As this cohort includes historic patients the new therapeutic schemes available today are expected to improve HRQOL in future.

  8. Health-related Quality of Life in Two Factories in Yasuj City

    OpenAIRE

    hamidreza Mokarami; ebrahim Taban; mohsen , Yazdani Aval; mohamad Taghavi; hossen Marioryad

    2015-01-01

    Background & aim: Work is an important component of QOL therefore work-related factors could be a significant predictor in this respect.The current study was aimed to asses QOL and its association with socio-demographic, health and work-related factors in two factories in Yasuj, Iran. Methods: In the present cross-sectional study, participants were 280 workers of two factories. The Persian version of World Health Organization Quality of Life-Brief (WHOQOL-BREF) was used to assess the QOL. ...

  9. Longitudinal health-related quality of life assessment: implications for prognosis in ovarian cancer

    OpenAIRE

    Gupta, Digant; Braun, Donald P.; Staren, Edgar D; Markman, Maurie

    2013-01-01

    Background There is no information in the literature on the impact of changes in quality of life (QoL) scores on prognosis in ovarian cancer. We investigated whether changes in QoL during treatment could predict survival in ovarian cancer patients. Methods We evaluated 137 ovarian cancer patients treated at our institution between Jan 2001 and Dec 2009 who were available for a minimum follow-up of 3 months. QoL was evaluated at baseline and after 3 months of treatment using EORTC-QLQ-C30. Cox...

  10. Health-related quality of life after stroke: reliability of proxy responses

    DEFF Research Database (Denmark)

    Muus, Ingrid; Petzold, Max; Ringsberg, Karin C

    2009-01-01

    A Danish version of the Stroke-Specific Quality of Life Scale (SSQOL-DK) has been developed for self-reporting; it contains 12 physical and psychosocial domains. The purpose of this study was (a) to assess the reliability of the proxy version of the SSQOL-DK and (b) to evaluate the influence of....... Proxies rated the amount of trouble significantly smaller (higher score) than the patients only in the domain Social Roles. The amount of trouble in the domain Family Roles received significantly higher ratings from noncohabitant proxies when compared with patients (lower score). The proxy version of the...

  11. A Disproportionate Burden of Care: Gender Differences in Mental Health, Health-Related Quality of Life, and Social Support in Mexican Multiple Sclerosis Caregivers

    Science.gov (United States)

    Perrin, Paul B.; Panyavin, Ivan; Morlett Paredes, Alejandra; Aguayo, Adriana; Macias, Miguel Angel; Rabago, Brenda; Picot, Sandra J. Fulton; Arango-Lasprilla, Juan Carlos

    2015-01-01

    Background. Multiple sclerosis (MS) rates in Latin America are increasing, and caregivers there experience reduced mental and physical health. Based on rigid gender roles in Latin America, women more often assume caregiving duties, yet the differential impact on women of these duties is unknown. Methods. This study examined gender differences in mental health (Patient Health Questionnaire-9, Satisfaction with Life Scale, Rosenberg Self-Esteem Scale, State-Trait Anxiety Inventory, and Zarit Burden Inventory), health-related quality of life (HRQOL; Short Form-36), and social support (Interpersonal Support Evaluation List-12) in 81 (66.7% women) Mexican MS caregivers. Results. As compared to men caregivers, women had lower mental health (p = 0.006), HRQOL (p < 0.001), and social support (p < 0.001). This was partially explained by women caregivers providing care for nearly twice as many hours/week as men (79.28 versus 48.48, p = 0.018) and for nearly three times as many months (66.31 versus 24.30, p = 0.002). Conclusions. Because gender roles in Latin America influence women to assume more substantial caregiving duties, MS caregiver interventions in Latin America—particularly for women caregivers—should address the influence of gender-role conformity on care and psychosocial functioning. PMID:26538818

  12. Validity, reliability, and responsiveness of a new short Visual Simplified Respiratory Questionnaire (VSRQ) for health-related quality of life assessment in chronic obstructive pulmonary disease.

    Science.gov (United States)

    Perez, T; Arnould, B; Grosbois, J-M; Bosch, V; Guillemin, I; Bravo, M-L; Brun, M; Tonnel, A-B

    2009-01-01

    The Visual Simplified Respiratory Questionnaire (VSRQ) was designed to assess health-related quality of life (HRQoL) in patients with chronic obstructive pulmonary disease (COPD). It contains eight items: dyspnea, anxiety, depressed mood, sleep, energy, daily activities, social activities and sexual life. Psychometric properties were assessed during a clinical trial that evaluated the impact of tiotropium on HRQoL of COPD patients. These included the determination of structure, internal consistency reliability, concurrent validity with the St George's Respiratory Questionnaire (SGRQ), test - retest reliability, clinical validity and responsiveness to change over two weeks. Minimal important difference (MID) was calculated; cumulative response curves (CRC) were based on the dyspnea item. Psychometric analyses showed that VSRQ structure was unidimensional. The questionnaire demonstrated good internal consistency reliability (Cronbach's alpha = 0.84), good concurrent validity with SGRQ (Spearman = -0.70) and clinical validity, good test-retest reproducibility (ICC = 0.77), and satisfactory responsiveness (standardized response mean = 0.57; Guyatt's statistic = 0.63). MID was 3.4; CRC median value of the 'minimally improved' patients was 3.5. In conclusion, VSRQ brevity and satisfactory psychometric properties make it a good candidate for large studies to assess HRQoL in COPD patients. Further validation is needed to extend its use in clinical practice. PMID:19436682

  13. A Disproportionate Burden of Care: Gender Differences in Mental Health, Health-Related Quality of Life, and Social Support in Mexican Multiple Sclerosis Caregivers

    Directory of Open Access Journals (Sweden)

    Paul B. Perrin

    2015-01-01

    Full Text Available Background. Multiple sclerosis (MS rates in Latin America are increasing, and caregivers there experience reduced mental and physical health. Based on rigid gender roles in Latin America, women more often assume caregiving duties, yet the differential impact on women of these duties is unknown. Methods. This study examined gender differences in mental health (Patient Health Questionnaire-9, Satisfaction with Life Scale, Rosenberg Self-Esteem Scale, State-Trait Anxiety Inventory, and Zarit Burden Inventory, health-related quality of life (HRQOL; Short Form-36, and social support (Interpersonal Support Evaluation List-12 in 81 (66.7% women Mexican MS caregivers. Results. As compared to men caregivers, women had lower mental health (p=0.006, HRQOL (p<0.001, and social support (p<0.001. This was partially explained by women caregivers providing care for nearly twice as many hours/week as men (79.28 versus 48.48, p=0.018 and for nearly three times as many months (66.31 versus 24.30, p=0.002. Conclusions. Because gender roles in Latin America influence women to assume more substantial caregiving duties, MS caregiver interventions in Latin America—particularly for women caregivers—should address the influence of gender-role conformity on care and psychosocial functioning.

  14. Effectiveness of cognitive behavioral therapy on health-related quality of life: An evaluation of therapies provided by trainee therapists.

    Science.gov (United States)

    Henriksson, Sophie; Anclair, Malin; Hiltunen, Arto J

    2016-06-01

    The present study was carried out to examine the treatment effect of cognitive behavioral therapy provided by trainee therapists at a university clinic, focusing on health-related quality of life (HRQOL) optimism and symptoms. The study was conducted through a repeated measures design and included a treatment group (n = 21), which received cognitive behavioral therapy for an average of 10.7 therapy sessions and a control group (n = 14), that was put on a wait list for 8.6 weeks on average. After treatment, the treatment group improved significantly concerning general health (p = 0.028) and optimism (p = 0.027). In addition, clients improved in several areas within mental health and displayed some reduction in anxiety symptoms. Concurrently, the results also indicated some improvement within the control group, which may have been caused by the initial therapeutic contact, expectancy effects or spontaneous remission. The study concluded that cognitive behavioral therapy provided by trainee therapists may have a positive effect on areas within HRQOL and optimism. PMID:27119256

  15. Exploring the Relationship between Noise Sensitivity, Annoyance and Health-Related Quality of Life in a Sample of Adults Exposed to Environmental Noise

    OpenAIRE

    Daniel Shepherd; David Welch; Renata Mathews; Kim N. Dirks

    2010-01-01

    The relationship between environmental noise and health is poorly understood but of fundamental importance to public health. This study estimated the relationship between noise sensitivity, noise annoyance and health-related quality of life in a sample of adults residing close to the Auckland International Airport, New Zealand. A small sample (n = 105) completed surveys measuring noise sensitivity, noise annoyance, and quality of life. Noise sensitivity was associated with health-related qual...

  16. Health-Related Quality of Life among Artisanal Fisherwomen/Shellfish Gatherers: Lower than the General Population.

    Science.gov (United States)

    Müller, Juliana Dos Santos; Falcão, Ila Rocha; Couto, Maria Carolina Barreto Moreira; Viana, Wendel da Silva; Alves, Ivone Batista; Viola, Denise Nunes; Woods, Courtney Georgette; Rêgo, Rita Franco

    2016-01-01

    Quality of life is an indicator of how well one perceives that he/she is functioning physically and mentally. The aim of this paper is to determine the health-related quality of life (HRQOL) of artisanal fisherwomen/shellfish gatherers from the Saubara municipality in Bahia, Brazil in comparison to the general population. A structured questionnaire was administered to a sample of 209 artisanal fisherwomen selected at random. The HRQOL questionnaire, known as the 36-Item Short-Form Health Survey version 1 (SF-36v01), was also used, having been translated and verified cross-culturally for the Brazilian population. Sociodemographic, lifestyle and comorbidity information was also collected. Chronic diseases and indicators of musculoskeletal disorders (MSDs) were self-reported. The study population consisted primarily of individuals between 30 and 45 years of age (78%), of self-classified races black or brown (96.2%), with no more than an elementary school education (77%) and married (64.6%). In all the SF-36v01 dimensions, the values in the sample were lower than in the general population of Brazil, which was used as the reference population. In the "Physical Health" domain (Physical Functioning; Physical Role Limitations; Bodily Pain; General Health Perception) a tendency toward a lower health-related quality of life was observed among those who were older, had a lower education level, and had a prevalence of MSDs, hypertension or arthritis. The interference of health conditions linked to the fisherwomen's work activities may contribute to lower HRQOL in all analyzed aspects, in comparison to the general population. In light of these findings, public health policies must consider these informal workers who contribute greatly to Brazil's economy and food system. PMID:27164118

  17. Longitudinal Association of Preference-Weighted Health-Related Quality of Life Measures and Substance Use Disorder Outcomes

    Science.gov (United States)

    Pyne, Jeffrey M.; Tripathi, Shanti; French, Michael; McCollister, Kathryn; Rapp, Richard C.; Booth, Brenda M.

    2010-01-01

    Aim Examine the construct validity of generic preference-weighted health-related quality of life measures in a sample of patients with a substance use disorder (SUD). Design Longitudinal (baseline and six-month follow-up) data from a research study that evaluated interventions to improve linkage and engagement with SUD treatment. Setting A central intake unit that referred patients to seven SUD treatment centers in a Midwestern US metropolitan area. Participants 495 persons with a SUD. Measurements Participants completed two preference-weighted measures: self-administered Quality of Well-Being scale (QWB-SA) and standard gamble weighted Medical Outcomes Study SF-12 (SF-6D). They were also administered two clinical assessments: all seven domains of the Addiction Severity Index (ASI) and a symptom checklist based on the DSM-IV. Construct validity was determined via the relationships between disease-specific SUD and generic measures. Findings In unadjusted analyses, the QWB-SA and SF-6D change scores were significantly correlated with six ASI subscale change scores, but not with employment status. In adjusted repeated measures analyses, 3/7 ASI subscale scores were significant predictors of QWB-SA and 5/7 ASI subscale scores were significant predictors of SF-6D. Abstinence and problematic use at follow-up were significant predictors of QWB-SA and SF-6D. Effect sizes ranged from 0.352 to 0.400 for abstinence and −0.484 to −0.585 for problematic use. Conclusions Generic preference-weighted health-related quality of life measures show moderate to good associations with substance-use specific measures and in certain circumstances can be used in their stead. This study provides further support for the use of the QWB-SA and SF-6D in clinical and economic evaluations of SUD interventions. PMID:21205046

  18. Integrating a health-related-quality-of-life module within electronic health records: a comparative case study assessing value added

    Directory of Open Access Journals (Sweden)

    Shea Christopher M

    2012-03-01

    Full Text Available Abstract Background Health information technology (HIT applications that incorporate point-of-care use of health-related quality of life (HRQL assessments are believed to promote patient-centered interactions between seriously ill patients and physicians. However, it is unclear how willing primary care providers are to use such HRQL HIT applications. The specific aim of this study was to explore factors that providers consider when assessing the value added of an HRQL application for their geriatric patients. Methods Three case studies were developed using the following data sources: baseline surveys with providers and staff, observations of staff and patients, audio recordings of patient-provider interactions, and semi-structured interviews with providers and staff. Results The primary factors providers considered when assessing value added were whether the HRQL information from the module was (1 duplicative of information gathered via other means during the encounter; (2 specific enough to be useful and/or acted upon, and; (3 useful for enough patients to warrant time spent reviewing it for all geriatric patients. Secondary considerations included level of integration of the HRQL and EHR, impact on nursing workflow, and patient reluctance to provide HRQL information. Conclusions Health-related quality of life modules within electronic health record systems offer the potential benefit of improving patient centeredness and quality of care. However, the modules must provide benefits that are substantial and prominent in order for physicians to decide that they are worthwhile and sustainable. Implications of this study for future research include the identification of perceived "costs" as well as a foundation for operationalizing the concept of "usefulness" in the context of such modules. Finally, developers of these modules may need to make their products customizable for practices to account for variation in EHR capabilities and practice

  19. Health-related quality of life and sense of coherence among Polish immigrants in Germany and indigenous Poles.

    Science.gov (United States)

    Morawa, Eva; Erim, Yesim

    2015-06-01

    Immigrants are faced with several impediments in the host country that may affect their quality of life (QoL), but little is known about the impact of these stressors as well as about the protective role of sense of coherence (SoC) in the context of Polish immigration to Germany. Health Related QoL (Short Form Health Survey SF-36) and SoC (Sense of Coherence Scale SOC-29) were assessed in a total sample consisting of 511 participants aged between 18 and 84 years (260 Polish immigrants in Germany and 251 indigenous Poles). Polish immigrants reported a significantly lower mental and physical health-related QoL than the German norm population, but they were comparable to native Poles. This result remained the same when the model was adjusted for age but physical health status was better for immigrants compared with indigenous Poles. Both groups scored significantly lower for SoC than Germans, but did not differ from each other. The main differences concerning the examined variables were with respect to the German norm population and are putatively shaped by culture. PMID:25593083

  20. Prisoners’ Health Related Quality of Life (HRQoL- A review

    Directory of Open Access Journals (Sweden)

    Togkas K.

    2014-04-01

    Full Text Available Background: The prisoners are a group with increased health needs. Aim: To evaluate HRQoL in prisoners. Μethods: A bibliographical review was conducted at the data base of Pubmed and Scholar Google. The quest included researches and reviews published in Greek and English language between 1985-2013. Results: Prisoners present low quality of life, poor perceived health condition and high morbidity in comparison with the general population. The percentage of morbidity from chronic and communicable diseases during the imprisonment is high. They present in high degree problems of drug, alcohol and smoking addiction and their HRQoL is adversely influenced. The prevalence of hepatitis C, B and HIV infection is also very high, although there is not enough information for this kind of prisoners. The frequency of some personality disorders, of suicides and mental disorders is extremely high. The HRQoL of these prisoners is worse in comparison with other prisoners. The environmental factors (isolation, bad relationships with the other prisoners, lack of contact with their family etc influence in a negative way the mental health and the HRQoL. Moreover, the influence of sexual lack has not been yet sufficiently studied. Women and elder prisoners have different needs from the other prisoners and worse quality of life in comparison with the general population. The ex- prisoners are at increased death risk due to drug overdose, cardiovascular diseases and suicide. Conclusion: The HRQoL and the self-reported health status of prisoners has not been studied extensively. Targeted strategies for the HRQoL improvement are being required. Indicatively the appliance of programs aimed to smoking ceasing, prevention of communicable diseases, stress management, drug detox is being proposed. The conduction of future surveys is essential in order for the consequences of imprisonment to be indicated as well as for the demographical, criminal or environmental factors which

  1. Vision Health-Related Quality of Life in Chinese Glaucoma Patients

    Directory of Open Access Journals (Sweden)

    Lei Zuo

    2015-01-01

    Full Text Available This cross-sectional study evaluated VRQOL in Chinese glaucoma patients and the potential factors influencing VRQOL. The VRQOL was assessed using the Chinese-version low vision quality of life questionnaire. Visual field loss was classified by the Hodapp-Parrish-Anderson method. The correlations of VRQOL to the best corrected visual acuity and the VF loss were investigated. The potential impact factors to VRQOL of glaucoma patients were screened by single factor analysis and were further analyzed by multiple regression analysis. There were significant differences in VRQOL scores between mild VF loss group and moderate VF loss group, moderate VF loss group and severe VF loss group, and mild VF loss group and severe VF loss group according to the better eye. In multiple linear regression, the binocular weighted average BCVA significantly affected the VRQOL scores. Binocular MD was the second influencing factor. In logistic regression, binocular severe VF loss and stroke were significantly associated with abnormal VRQOL. Education was the next influencing factor. This study showed that visual acuity correlated linearly with VRQOL, and VF loss might reach a certain level, correlating with abnormal VRQOL scores. Stroke was significantly associated with abnormal VRQOL.

  2. Health-related quality of life of patients 12 months following surgical intensive care discharge

    OpenAIRE

    F. Karachi; S. Hanekom; Faure, M.

    2011-01-01

    Health  related  quality  of  life  (HRQoL)  and  the  effect  of  selected  socio-demographic  and  clinical  intensive  care  variables  on  HRQoL of  patients  12  months  following  adult  surgical  intensive  care  unit  discharge in  the  Western  Cape  was  evaluated.  A  prospective  observational  study  was conducted.  The  sample  comprised  46  patients  who  had  survived  12  months following discharge. Structured telephonic interviews were conducted using a self-developed  and ...

  3. Cannabis use and mental health-related quality of life among individuals with depressive disorders.

    Science.gov (United States)

    Aspis, Itay; Feingold, Daniel; Weiser, Mark; Rehm, Jurgen; Shoval, Gal; Lev-Ran, Shaul

    2015-12-15

    Cannabis is the most widely used illicit substance among individuals with depressive disorders. This study aimed to evaluate whether among individuals with depressive disorders, higher frequency of cannabis use would be associated with poorer Quality of Life (QoL), based on a large nationally representative US sample. Individuals with depressive disorders (N=3416) were divided into categories according to no use (N=3096), occasional use (less than weekly, N=176) and regular (at least weekly, N=144) use of cannabis in the past 12 months. QoL was assessed using the Short-Form 12 (SF-12) questionnaire. Women who used cannabis regularly had a significantly lower SF-12 Mental Component Summary score (MCS) compared to non-users, with a mean difference of 0.4 Standard Deviations (SDs). Comparison of subscale scores showed no significant differences. No significant difference was noted when comparing women who used cannabis occasionally to non-users. No differences were found among men when comparing MCS and mental subscale scores of both regular and occasional users to non-users. Our findings highlight the importance of taking gender and the frequency of cannabis use into account, when assessing functional and emotional aspects of cannabis use among individuals with depressive disorders. PMID:26388103

  4. Influence of obesogenic behaviors on health-related quality of life in adolescents.

    Science.gov (United States)

    Gopinath, Bamini; Louie, Jimmy C Y; Flood, Victoria M; Burlutsky, George; Hardy, Louise L; Baur, Louise A; Mitchell, Paul

    2014-01-01

    We aimed to prospectively examine the association between the combined effects of obesogenic behaviors on quality of life (QOL) in adolescents. Of 2353 Sydney schoolchildren surveyed (median age 12.7 years), 1,213 were re-examined 5 years later at age 17-18. Children completed activity and food-frequency questionnaires. An unhealthy behavior score was calculated, allocating 1 point for the following: Boys reporting 4 or 5 lifestyle risk factors compared to their peers reporting none or one at baseline, had lower total and physical summary scores at follow-up, ptrend=0.02 and 0.01, respectively. Girls engaging in 4 or 5 versus 0 or 1 unhealthy behaviors, had 4.6-units lower physical summary score (ptrend=0.04), five years later. The number of obesogenic lifestyle risk factors was independently associated with subsequent poorer QOL, particularly physical health, during adolescence. These findings underscore the importance of targeting lifestyle behaviors to promote general well-being and physical functioning in adolescents. PMID:24561980

  5. Factors influencing health-related quality of life in chronic liver disease

    Institute of Scientific and Technical Information of China (English)

    Abhasnee Sobhonslidsuk; Chatchawan Silpakit; Ronnachai Kongsakon; Patchareeya Satitpornkul; Chaleaw Sripetch; Anya Khanthavit

    2006-01-01

    AIM: To investigate the factors contributing to healthrelated quality of life (HRQL) in chronic liver disease (CLD).METHODS: Patients with CLD and age- and sexmatched normal subjects performed the validated Thai versions of the short-form 36 (SF-36) by health survey and chronic liver disease questionnaire (CLDQ). Stepwise multiple regression analysis was used to assess the impact of disease severity, demography, causes of CLD,socioeconomic factors, and self-rating health perception on HRQL.RESULTS: Two-hundred and fifty patients with CLD and fifty normal subjects were enrolled into the study. Mean age and the numbers of low educated, unemployed,blue-collar career and poor health perception increased significantly from chronic hepatitis to Child's Classes A to B to C. Advanced stage of CLD was related to deterioration of HRQL. Increasing age and female reduced physical health area. Low socioeconomic factors and financial burden affected multiple areas of HRQL.In overall, the positive impact of self-rating health perception on HRQL was consistently showed.CONCLUSION: Advanced stages of chronic liver disease, old age, female sex, low socioeconomic status and financial burden are important factors reducing HRQL. Good health perception improves HRQL regardless of stages of liver disease.

  6. Development of a health-related quality of life questionnaire for Thai patients with rhinoconjunctivitis.

    Science.gov (United States)

    Bunnag, Chaweewan; Leurmarnkul, Watcharee; Jareoncharsri, Perapun; Ungkanont, Kitirat; Tunsuriyawong, Prayuth; Kosrirukvongs, Panida; Sriussadaporn, Pornsri; Musiksukont, Srisomboon; Kosawanon, Somying; Chairojkanjana, Kraisorn

    2004-01-01

    The objective of this study was to develop a disease-specific questionnaire for patients with rhinoconjunctivitis. All patients were recruited at the Out-Patient Clinic at Siriraj Hospital. Related topics were gathered from several sources, and a list of 63 items was produced. In phase I, the first version of the questionnaire was completed by 363 patients. Forty-eight items were identified by clinical impact analysis during the item removal process, two more questions were then added, giving a total of 50. Two hundred and forty-three patients completed the second version questionnaire in phase II. The average time taken to complete the questionnaire was 6.38 minutes. The item removal process in phase II was achieved by a multi-step process. There were 36 items in the third version questionnaire which consisted of six dimensions and two independent items as follows: symptoms (17 items), physical functioning (3 items), role limitations (3 items), sleep (3 items), social functioning (3 items), emotions (5 items), general health (1 item), and absenteeism (1 item). The scores of each item ranged from 1 to 5; a lower score indicating a better quality of life. Data from the selected 36 items was extracted to test the validity and reliability of the final version. The floor and ceiling effects of the scores for each dimension were low. Multitrait multi-item analysis was conducted to examine construct validity. The scaling success of convergent and divergent validity was 100% and 94%, respectively. Internal consistency determined by Cronbach's alpha coefficient, was satisfactory (0.79-0.87). The study indicates that the questionnaire is suitable for use in clinical settings. While the test results are encouraging, further work needs to be done on the test-retest reliability and on responsiveness. PMID:15565942

  7. Health-related quality of life, optimism, and coping strategies in persons suffering from localized scleroderma.

    Science.gov (United States)

    Szramka-Pawlak, B; Dańczak-Pazdrowska, A; Rzepa, T; Szewczyk, A; Sadowska-Przytocka, A; Żaba, R

    2013-01-01

    The clinical course of localized scleroderma may consist of bodily deformations, and bodily functions may also be affected. Additionally, the secondary lesions, such as discoloration, contractures, and atrophy, are unlikely to regress. The aforementioned symptoms and functional disturbances may decrease one's quality of life (QoL). Although much has been mentioned in the medical literature regarding QoL in persons suffering from dermatologic diseases, no data specifically describing patients with localized scleroderma exist. The aim of the study was to explore QoL in localized scleroderma patients and to examine their coping strategies in regard to optimism and QoL. The study included 41 patients with localized scleroderma. QoL was evaluated using the SKINDEX questionnaire, and levels of dispositional optimism were assessed using the Life Orientation Test-Revised. In addition, individual coping strategy was determined using the Mini-MAC scale and physical condition was assessed using the Localized Scleroderma Severity Index. The mean QoL score amounted to 51.10 points, with mean scores for individual components as follows: symptoms = 13.49 points, emotions = 21.29 points, and functioning = 16.32 points. A relationship was detected between QoL and the level of dispositional optimism as well as with coping strategies known as anxious preoccupation and helplessness-hopelessness. Higher levels of optimism predicted a higher general QoL. In turn, greater intensity of anxious preoccupied and helpless-hopeless behaviors predicted a lower QoL. Based on these results, it may be stated that localized scleroderma patients have a relatively high QoL, which is accompanied by optimism as well as a lower frequency of behaviors typical of emotion-focused coping strategies. PMID:23398519

  8. Costs in Relation to Disability, Disease Activity, and Health-related Quality of Life in Rheumatoid Arthritis

    DEFF Research Database (Denmark)

    Wallman, Johan K; Eriksson, Jonas K; Nilsson, Jan-Åke;

    2016-01-01

    OBJECTIVE: To compare how costs relate to disability, disease activity, and health-related quality of life (HRQOL) in rheumatoid arthritis (RA). METHODS: Antitumor necrosis factor (anti-TNF)-treated patients with RA in southern Sweden (n = 2341) were monitored 2005-2010. Health Assessment...... Questionnaire (HAQ), 28-joint Disease Activity Score (DAS28), and EQ-5D scores were linked to register-derived costs of antirheumatic drugs (excluding anti-TNF agents), patient care, and work loss from 30 days before to 30 days after each visit (n = 13,289). Associations of HAQ/DAS28/EQ-5D to healthcare...... (patient care and drugs) and work loss costs (patients costs. Analyses were conducted based on both individual means (linear regression, comparing...

  9. Feasibility Study: Colombian Caribbean Folk Dances to Increase Physical Fitness and Health-Related Quality of Life in Older Women.

    Science.gov (United States)

    Pacheco, Ernesto; Hoyos, Diana P; Watt, Willinton J; Lema, Lucía; Arango, Carlos M

    2016-04-01

    The objectives of the study were to describe the feasibility of an intervention in older women based on folk dances of the Colombian Caribbean region, and to analyze the effects of the intervention on physical fitness and health-related quality of life (HRQoL). A pilot study was conducted in a sample of 27 participants, 15 in the intervention group (IG) and 12 in the comparison group (CG). Caribbean Colombian dance rhythms were introduced as an intervention that lasted 12 weeks. Recruitment and retention was not optimal. Treatment fidelity components indicated that intervention was administered as intended. IG participants showed positive and statistically significant changes in some components of physical fitness. No significant changes were observed in HRQoL indicators for either group. In conclusion, the intervention was feasible, but recruitment and retention was challenging. Folk dances of the Colombian Caribbean region provoked significant results in physical fitness but not in HRQoL. PMID:26371771

  10. Health-related quality of life after adjuvant and salvage postoperative radiotherapy for prostate cancer - A prospective analysis

    International Nuclear Information System (INIS)

    Background and purpose: The aim of the study was to analyze health-related quality of life changes after postoperative radiotherapy (RT) for prostate cancer. Materials and methods: A group of 101 patients has been surveyed prospectively before (time A), at the last day (B), two months after (C) and >1 year after (D) RT using a validated questionnaire (Expanded Prostate Cancer Index Composite) with urinary, bowel, sexual and hormonal domains. The prostatic fossa was treated with a four-field box technique up to a total dose of 66.6 Gy. Results: While median urinary scores reached baseline levels already two months after radiotherapy (function/bother scores at time A-B-C-D: 94/89-89/75-94/89-94/89; A vs. B: p 1 year, only minor HRQOL changes occurred in comparison to baseline scores

  11. Religiosity and Health-Related Quality of Life: A Cross-Sectional Study on Filipino Christian Hemodialysis Patients.

    Science.gov (United States)

    Cruz, Jonas Preposi; Colet, Paolo C; Qubeilat, Hikmet; Al-Otaibi, Jazi; Coronel, Erwin I; Suminta, Roderick C

    2016-06-01

    This study aimed to measure the religiosity and health-related quality of life of Filipino Christian HD patients. A cross-sectional study of 100 HD patients was conducted. The Duke University Religion Index and the Ferrans and Powers QLI Dialysis Version-III were used. Data were analyzed using descriptive statistics and Pearson r correlation. Attendance to organizational religious activities and NORA were found to be correlated with some of the dimensions of HRQoL. Intrinsic religiosity showed a strong, positive correlation with HRQoL. It is essential to attend to and nourish their religious needs. Holistic approach in providing care to HD patients, with emphasis on spiritual care, is encouraged to improve their total health. PMID:26289995

  12. [Health-related quality of life and factors associated with overweight and obesity in the pediatric population of Catalonia, Spain].

    Science.gov (United States)

    Rajmil, Luis; López-Aguilá, Sílvia; Mompart-Penina, Anna

    2011-12-01

    The aim of this work is to describe the health-related quality of life (HRQOL), and to analyze the associated factors to overweight/obesity in a representative sample of the Catalan population 0-14 years old. Proxyrespondents answered the child's questionnaire of the Encuesta de Salud de Cataluna (ESCA) 2006 (n = 2.200). Variables analyzed were weight and height, the KIDSCREEN-10 HRQOL questionnaire, and also scales on risky behaviors, physical activity, frequency of fast food consumption, and number of hours of television viewing. Logistic regression models were adjusted. In 31% of children HRQOL was excellent/very good. Risky behaviors and restriction of activity were the associated factors to the best and the worst HRQOL. Maternal level of education and some habits and behaviors were associated to overweight/obesity. The ESCA contributes with useful information to monitor and to assess interventions addressed to the children population. PMID:22310362

  13. Trends in Health-Related Quality of Life Among Adolescents in the United States, 2001–2010

    Directory of Open Access Journals (Sweden)

    Wanjun Cui, PhD

    2013-07-01

    Full Text Available Health-related quality of life (HRQOL measures are often used to track changes in population health, mostly among adults. Prompted by the recent US recession, we assessed trends in adolescent HRQOL by using cross-sectional data from the 2001–2010 National Health and Nutrition Examination Survey. Adolescents’ self-rated health and reported mental health declined significantly, especially among those in low-income families, but their physical health and activity limitation did not change. Because these HRQOL declines occurred at the end of the decade and especially among adolescents from low-income families, we conclude that these declines are consistent with recession effects and warrant further study.

  14. Intensive care delirium - effect on memories and health-related quality of life - a follow-up study

    DEFF Research Database (Denmark)

    Svenningsen, Helle; Tønnesen, Else K; Videbech, Poul;

    2013-01-01

    after intensive care unit. Interviews were repeated after two and six months and supplemented with Short Form-36 and the Barthel Index. RESULTS: Delirium was detected in 60% of the patients in our study, and delirious patients had significantly fewer factual memories and more memories of delusion than...... nondelirious patients up to six months postintensive care unit discharge. Delirium, memories and intensive care unit diaries with follow-up did not affect health-related quality of life and healthcare dependency. Memories of delusions might have an impact on patients assessed as nondelirious. CONCLUSIONS: More...... than half of the patients in intensive care unit experience delirium, which is associated with fewer factual memories and more memories of delusions. Short Form-36 might not be sensitive to delirium-related outcomes. Future research should include the development of better assessment tools to determine...

  15. Health-related personal control predicts depression symptoms and quality of life but not health behaviour following coronary artery bypass graft surgery.

    Science.gov (United States)

    Kidd, Tara; Poole, Lydia; Leigh, Elizabeth; Ronaldson, Amy; Jahangiri, Marjan; Steptoe, Andrew

    2016-02-01

    To determine the prospective association between health-related control beliefs, quality of life (QOL), depression symptoms, and health behaviours in coronary artery bypass graft (CABG) patients 6-8 weeks following surgery. 149 patients who were undergoing planned CABG surgery were recruited. Patients completed questionnaires measuring health related personal control, treatment control, depression symptoms, QOL, and health behaviours prior to and 6-8 weeks after surgery. Higher levels of health-related personal control predicted better QOL, and lower levels of depression symptoms, but not adherence to medication, cardiac rehabilitation attendance, or physical activity. These results were independent of demographic, behavioural, and clinical covariates. Treatment control was not associated with any outcome. These results suggest that perceived health-related personal control is associated with key aspects of short-term recovery from CABG surgery. Targeted interventions aimed at improving perceptions of health-related personal control may improve health outcomes in this cardiac population. PMID:26341356

  16. Validation of Chinese Version of Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (Chi-PCOSQ.

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    Chung-Ying Lin

    Full Text Available To evaluate the responsiveness, longitudinal validity, and measurement invariance of the Chinese version of the Polycystic Ovary Syndrome Health-related Quality of Life Questionnaire (Chi-PCOSQ.This prospective study was conducted in a medical center in southern Taiwan. 102 women aged 18-45 years and diagnosed with PCOS were enrolled. Objective indicators for clinical changes of PCOS included assessing the 2-hour glucose and insulin levels before and after treatment. The responsiveness of Chi-PCOSQ and WHOQOL-BREF was analyzed using paired t-tests and the standard response mean. Confirmatory factor analysis was performed to assess the measurement invariance of Chi-PCOSQ.With improved 2-hour glucose and insulin levels, we also found significantly increased Chi-PCOSQ total and individual domain scores (total score: t (49 = 5.20; p < 0.001, domain scores: t (49 = 2.72 to 3.87; p < 0.01, except for hair growth. Half of the domains scores (3 of 6 and the total score of Chi-PCOSQ had a medium responsiveness, but WHOQOL-BREF was not sufficiently responsive to clinical changes of PCOS. Improved PCOS-specific health-related quality of life (HRQoL, as indicated by Chi-PCOSQ scores, was significantly associated with improved 2-hour glucose and insulin levels. All indices of the data-model fit of the Chi-PCOSQ structure were satisfactory, except for the slightly high standardized root mean square residual values (0.087 to 0.088. The measurement invariance of Chi-PCOSQ was supported across time.Chi-PCOSQ is sufficiently sensitive in detecting clinical changes and its measurement structure is suitable for Chinese women with PCOS. It is thus a promising tool for assessing the HRQoL of ethnic Chinese women with PCOS.

  17. Impact of obesity and type 2 diabetes on health-related quality of life in the general population in England

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    Stephen CL Gough

    2009-11-01

    Full Text Available Stephen CL Gough,1 Nana Kragh,2 Uffe Jon Ploug,2 Mette Hammer21University of Birmingham and University Hospital Birmingham NHS Foundation Trust, Birmingham, UK; 2Novo Nordisk A/S Global Health Economics and Outcomes Research Krogshojvej 55, DK-2880 Bagsvaerd, DenmarkBackground: Weight gain can contribute towards the development of type 2 diabetes (T2D, and some treatments for T2D can lead to weight gain. The aim of this study was to determine whether having T2D and also being obese had a greater or lesser impact on health-related quality of life (HRQoL than having either of the two conditions alone.Methods: The 2003 dataset of the Health Survey for England (HSE was analyzed using multiple regression analyses to examine the influence of obesity and T2D on HRQoL, and to determine whether there was any interaction between these two disutilities.Results: T2D reduced HRQoL by 0.029 points, and obesity reduced HRQoL by 0.027 points. There was no significant interaction effect between T2D and obesity, suggesting that the effect of having both T2D and being obese is simply additive and results in a reduction in HRQoL of 0.056.Conclusions: Based on analysis of HSE 2003 data, people with either T2D or obesity experience significant reduction in HRQoL and people with both conditions have a reduction in HRQoL equal to the sum of the two independent effects. The effect of obesity on HRQoL in people with T2D should be considered when selecting a therapy.Keywords: diabetes, health-related quality of life, obesity, type 2 diabetes, England

  18. Health-related quality of life in children with newly diagnosed cancer: a one year follow-up study

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    Niggli Felix K

    2006-09-01

    Full Text Available Abstract Background Most studies on health-related quality of life (HRQOL in children with cancer focussed on survivors. Only few studies have evaluated patients during ongoing oncological treatment. The aim of this study was a prospective assessment of HRQOL in children during the first year after diagnosis of cancer and an examination of demographic, medical, and parental predictors of HRQOL. Methods Fifty-two patients (mean age: 10.9 years were assessed 6 weeks and 1 year after diagnosis with the TNO-AZL Questionnaire for Children's Health-Related Quality of Life. Parents completed the Brief Symptom Inventory. Results Compared to a community sample, patients reported more physical complaints, reduced motor functioning and autonomy, and impaired positive emotional functioning 6 weeks after diagnosis. HRQOL significantly improved over the year. However, at 1 year, patients still showed reduced motor and emotional functioning. At 6 weeks, children with leukemia were most affected. At 1 year, patients with brain tumors complained about more physical symptoms than the other groups. Intensity of treatment and presence of medical complications mainly influenced HRQOL at 6 weeks but less at 1 year. Parental psychopathology was associated with better cognitive functioning in the child. Conclusion This prospective study found several domains of HRQOL to be compromised 6 weeks and 1 year after the diagnosis of cancer. Although HRQOL significantly increased over the year, there were important differences between diagnostic groups. The findings highlight the importance of repeated evaluation of HRQOL in children undergoing cancer treatment and consideration of specific differences between diagnostic groups.

  19. Improving health-related quality of life through an evidence-based obesity reduction program: the Healthy Weights Initiative

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    Lemstra ME

    2016-03-01

    Full Text Available Mark E Lemstra,1 Marla R Rogers,21Alliance Health, Moose Jaw, 2Department of Physical Medicine and Rehabilitation, College of Medicine, University of Saskatchewan, Saskatoon, SK, Canada Abstract: When evaluating any health intervention, it is critical to include the impact of the intervention on health-related quality of life (HRQL. Among those who are obese, HRQL is often lower than the general population and even more when considering obesity-related comorbidities and bodily pain. The objectives of this paper were to determine the impact of a multidisciplinary, community-based obesity reduction program on HRQL and to determine the independent risk factors for lack of improvement from baseline to follow-up. HRQL was measured using the Medical Outcomes Study 36-Item Short-Form Health Survey (SF-36 at baseline and follow-up (24 weeks. To date, 84.5% of those who completed the program had improvements in their overall SF-36 score. Significant increases in the mean scores on eight dimensions of health were also observed. Lack of improvement was independently affected by smoking status (odds ratio 3.75; 95% confidence interval 1.44–9.78; P=0.007 and not having a buddy to attend the program (odds ratio 3.70; 95% confidence interval 1.28–10.68; P=0.015. Obesity reduction programs that target increasing exercise, improving diet, and cognitive behavioral therapy can positively impact HRQL in obese adults. Social support has a strong role to play in improving outcomes. Keywords: obesity, health-related quality of life, social- support, SF-36, Canada

  20. Validation of Chinese Version of Polycystic Ovary Syndrome Health-Related Quality of Life Questionnaire (Chi-PCOSQ)

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    Lin, Chung-Ying; Ou, Huang-tz; Wu, Meng-Hsing; Chen, Pei-Chi

    2016-01-01

    Objectives To evaluate the responsiveness, longitudinal validity, and measurement invariance of the Chinese version of the Polycystic Ovary Syndrome Health-related Quality of Life Questionnaire (Chi-PCOSQ). Research Design and Method This prospective study was conducted in a medical center in southern Taiwan. 102 women aged 18–45 years and diagnosed with PCOS were enrolled. Objective indicators for clinical changes of PCOS included assessing the 2-hour glucose and insulin levels before and after treatment. The responsiveness of Chi-PCOSQ and WHOQOL-BREF was analyzed using paired t-tests and the standard response mean. Confirmatory factor analysis was performed to assess the measurement invariance of Chi-PCOSQ. Results With improved 2-hour glucose and insulin levels, we also found significantly increased Chi-PCOSQ total and individual domain scores (total score: t (49) = 5.20; p PCOS. Improved PCOS-specific health-related quality of life (HRQoL), as indicated by Chi-PCOSQ scores, was significantly associated with improved 2-hour glucose and insulin levels. All indices of the data-model fit of the Chi-PCOSQ structure were satisfactory, except for the slightly high standardized root mean square residual values (0.087 to 0.088). The measurement invariance of Chi-PCOSQ was supported across time. Conclusion Chi-PCOSQ is sufficiently sensitive in detecting clinical changes and its measurement structure is suitable for Chinese women with PCOS. It is thus a promising tool for assessing the HRQoL of ethnic Chinese women with PCOS. PMID:27124836